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Sample records for superimposed electromyostimulation ems

  1. Physiological responses and perceived exertion during cycling with superimposed electromyostimulation.

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    Wahl, Patrick; Schaerk, Jonas; Achtzehn, Silvia; Kleinöder, Heinz; Bloch, Wilhelm; Mester, Joachim

    2012-09-01

    The goal of the study was to evaluate and to quantify the effects of local electromyostimulation (EMS) during cycling on the cardiorespiratory system, muscle metabolism, and perceived exertion compared with cycling with no EMS. Ten healthy men (age: 24.6 ± 3.2 years, V[Combining Dot Above]O2max: 54.1 ± 6.0 ml·min·kg) performed 3 incremental cycle ergometer step tests, 1 without and 2 with EMS (30 and 85 Hz) until volitional exhaustion. Lactate values and respiratory exchange ratio were significantly higher at intensities ≥75% peak power output (PPO) when EMS was applied. Bicarbonate concentration, base excess (BE), and Pco2 were significantly lower when EMS was applied compared with the control at intensities ≥75% PPO. Saliva cortisol levels increased because of the exercise but were unaffected by EMS. Furthermore, EMS showed greater effects on CK levels 24 hours postexercise than normal cycling did. Rating of perceived exertion was significantly higher at 100% PPO with EMS. No statistical differences were found for heart rate, pH, and Po2 between the tested cycling modes. The main findings of this study are greater metabolic changes (lactate, respiratory exchange ratio, BE, (Equation is included in full-text article.), Pco2) during cycling with EMS compared with normal cycling independent of frequency, mainly visible at higher work rates. Because metabolic alterations are important for the induction of cellular signaling cascades and adaptations, these results lead to the hypothesis that applied EMS stimulations during cycling exercise might be an enhancing stimulus for skeletal muscle metabolism and related adaptations. Thus, superimposed EMS application during cycling could be beneficial to aerobic performance enhancements in athletes and in patients who cannot perform high workloads. However, the higher demand on skeletal muscles involved must be considered.

  2. Acute effects of superimposed electromyostimulation during cycling on myokines and markers of muscle damage

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    Wahl, P.; Hein, M.; Achtzehn, S.; Bloch, W.; Mester, J.

    2015-01-01

    Objectives: The purpose of the present study was to evaluate the effects of superimposed electromyostimulation (E) during cycling on myokines and markers of muscle damage, as E might be a useful tool to induce a high local stimulus to skeletal muscle during endurance training without performing high external workloads. Methods: 13 subjects participated in three experimental trials each lasting 60 min in a randomized order. 1) Cycling (C), 2) Cycling with superimposed E (C+E) and 3) E. Interleukin-6 (IL-6), brain-derived neurotrophic factor (BDNF), creatine kinase (CK) and myoglobin were determined before (pre) and 0’, 30’, 60’, 240’ and 24h after each intervention. Results: Only C+E caused significant increases in levels of CK and myoglobin. BDNF and IL-6 significantly increased after C and C+E, however increases for IL-6 were significantly higher after C+E compared to C. Conclusion: The present study showed that superimposed E during cycling might be a useful tool to induce a high local stimulus to skeletal muscle even when performing low to moderate external workloads. This effect might be due the activation of additional muscle fibers and mild eccentric work due to the concomitant activation of agonist and antagonist. However the higher load to skeletal muscle has to be taken into account. PMID:25730652

  3. Effects of combined electromyostimulation and gymnastics training in prepubertal girls.

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    Deley, Gaëlle; Cometti, Carole; Fatnassi, Anaïs; Paizis, Christos; Babault, Nicolas

    2011-02-01

    This study investigated the effects of a 6-week combined electromyostimulation (EMS) and gymnastic training program on muscle strength and vertical jump performance of prepubertal gymnasts. Sixteen young women gymnasts (age 12.4 ± 1.2 yrs) participated in this study, with 8 in the EMS group and the remaining 8 as controls. EMS was conducted on knee extensor muscles for 20 minutes 3 times a week during the first 3 weeks and once a week during the last 3 weeks. Gymnasts from both groups underwent similar gymnastics training 5-6 times a week. Isokinetic torque of the knee extensors was determined at different eccentric and concentric angular velocities ranging from -60 to +240° per second. Jumping ability was evaluated using squat jump (SJ), counter movement jump (CMJ), reactivity test, and 3 gymnastic-specific jumps. After the first 3 weeks of EMS, maximal voluntary torque was increased (+40.0 ± 10.0%, +35.3 ± 11.8%, and +50.6 ± 7.7% for -60, +60, and +240°s⁻¹, respectively; p gymnasts, a 6-week EMS program, combined with the daily gymnastic training, induced significant increases both in knee extensor muscle strength and nonspecific and some specific jump performances.

  4. Effect of transcutaneous electromyostimulation on pressure pain threshold and tolerance in athletes under eccentric exercise

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    Selman Burak UĞURLU

    2014-08-01

    Full Text Available Exercise - induced hypoalgesia typically reported during and / or follow ing exercise. In this study, we investigated the role of transcutaneous electromyostimulation (EMS on pressure pain threshold and tolerance in athletes under eccentric exercise. Eleven male athletes aged 23,125 ± 0,99 years with 10,25 ± 2,66 years of athl etic training were recruited for this study . Following baseline measurements of pressure pain threshold and tolerance from m. biceps brachii and m. triceps brachii muscle and myofascial regions of the dominant upper extremity by using a digital algometer, subjects were underwent an acute bout of eccentric exercise. Participants were completed 4 sets of eccentric exercise each comprising 20 repetitions of lifting 80% of their 1 RM by using a dumbbell. Pressure pain threshold and tolerance tests were repeated 10, 20 and 30 minutes, and 24 and 48 hours following exercise. One week after acute exercise protocol, EMS protocol was applied to the participants immediately following eccentric exercise, and all measurements were repeated at the same timeline as eccent ric exercise. Standard EMS protocol at active recovery mode for 10 minutes was applied to the m. biceps brachii muscle by using surface electrodes. Results are presented as mean + standarts deviation. Data of the same timeline were analyzed by using repeat ed measures of ANOVA followed by Tukey’s post hoc test . A level of p<0.05 was accepted statistical significant. Eccentric exercise resulted to increase the pain tolerence in athletes, and EMS was found to decrease the pain tolerence 10 and 20 minutes at th e muscle region, and 10 and 30 minutes, and 24 hours at the myofascial region of m. biceps brachii, 10 min and 24 hr from muscle region, 10 and 30 min and 24 hr from myofascial region of M. triceps brachii following acute bout of eccentric exercise. We con cluded that EMS at active recovery phase mitigates the the hypoalgesic response following single bout of

  5. [Superimposed lichen planus pigmentosus].

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    Monteagudo, Benigno; Suarez-Amor, Óscar; Cabanillas, Miguel; de Las Heras, Cristina; Álvarez, Juan Carlos

    2014-05-16

    Lichen planus pigmentosus is an uncommon variant of lichen planus that is characterized by the insidious onset of dark brown macules in sun-exposed areas and flexural folds. Superimposed linear lichen planus is an exceedingly rare disorder, but it has been found in both lichen planopilaris and lichen planus types. A 39-year-old woman is presented showing a segmental and linear lichen planus associated with non-segmental lesions meeting all criteria for the diagnosis of superimposed linear planus pigmentosus. The segmental lesions were always more pronounced.

  6. Effects of whole-body electromyostimulation on resting metabolic rate, body composition, and maximum strength in postmenopausal women: the Training and ElectroStimulation Trial.

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    Kemmler, Wolfgang; Schliffka, Rebecca; Mayhew, Jerry L; von Stengel, Simon

    2010-07-01

    We evaluated the effect of whole-body electromyostimulation (WB-EMS) during dynamic exercises over 14 weeks on anthropometric, physiological, and muscular parameters in postmenopausal women. Thirty women (64.5 +/- 5.5 years) with experience in physical training (>3 years) were randomly assigned either to a control group (CON, n = 15) that maintained their general training program (2 x 60 min.wk of endurance and dynamic strength exercise) or to an electromyostimulation group (WB-EMS, n = 15) that additionally performed a 20-minute WB-EMS training (2 x 20 min.10 d). Resting metabolic rate (RMR) determined from spirometry was selected to indicate muscle mass. In addition, body circumferences, subcutaneous skinfolds, strength, power, and dropout and adherence values. Resting metabolic rate was maintained in WB-EMS (-0.1 +/- 4.8 kcal.h) and decreased in CON (-3.2+/-5.2 kcal.h, p = 0.038); although group differences were not significant (p = 0.095), there was a moderately strong effect size (ES = 0.62). Sum of skinfolds (28.6%) and waist circumference (22.3%) significantly decreased in WB-EMS whereas both parameters (1.4 and 0.1%, respectively) increased in CON (p = 0.001, ES = 1.37 and 1.64, respectively), whereas both parameters increased in CON (1.4 and 0.1%, respectively). Isometric strength changes of the trunk extensors and leg extensors differed significantly (p < or = 0.006) between WB-EMS and CON (9.9% vs. -6.4%, ES = 1.53; 9.6% vs. -4.5%, ES = 1.43, respectively). In summary, adjunct WB-EMS training significantly exceeds the effect of isolated endurance and resistance type exercise on fitness and fatness parameters. Further, we conclude that for elderly subjects unable or unwilling to perform dynamic strength exercises, electromyostimulation may be a smooth alternative to maintain lean body mass, strength, and power.

  7. Whole-Body Electromyostimulation to Fight Osteopenia in Elderly Females: The Randomized Controlled Training and Electrostimulation Trial (TEST-III

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    Simon von Stengel

    2015-01-01

    Full Text Available Whole-body electromyostimulation (WB-EMS has been shown to be effective in increasing muscle strength and mass in elderly women. Because of the interaction of muscles and bones, these adaptions might be related to changes in bone parameters. 76 community-living osteopenic women 70 years and older were randomly assigned to either a WB-EMS group (n=38 or a control group (CG: n=38. The WB-EMS group performed 3 sessions every 14 days for one year while the CG performed gymnastics containing identical exercises without EMS. Primary study endpoints were bone mineral density (BMD at lumbar spine (LS and total hip (thip as assessed by DXA. After 54 weeks of intervention, borderline nonsignificant intergroup differences were determined for LS-BMD (WB-EMS: 0.6±2.5% versus CG -0.7±2.5%, P=.051 but not for thip-BMD (WB-EMS: -1.1±1.9% versus CG: -0.8±2.3%, P=.771. With respect to secondary endpoints, there was a gain in lean body mass (LBM of 1.5% (P=.006 and an increase in grip strength of 8.4% (P=.000 in the WB-EMS group compared to CG. WB-EMS effects on bone are less pronounced than previously reported effects on muscle mass. However, for subjects unable or unwilling to perform intense exercise programs, WB-EMS may be an option for maintaining BMD at the LS.

  8. Whole-Body Electromyostimulation to Fight Osteopenia in Elderly Females: The Randomized Controlled Training and Electrostimulation Trial (TEST-III).

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    von Stengel, Simon; Bebenek, Michael; Engelke, Klaus; Kemmler, Wolfgang

    2015-01-01

    Whole-body electromyostimulation (WB-EMS) has been shown to be effective in increasing muscle strength and mass in elderly women. Because of the interaction of muscles and bones, these adaptions might be related to changes in bone parameters. 76 community-living osteopenic women 70 years and older were randomly assigned to either a WB-EMS group (n = 38) or a control group (CG: n = 38). The WB-EMS group performed 3 sessions every 14 days for one year while the CG performed gymnastics containing identical exercises without EMS. Primary study endpoints were bone mineral density (BMD) at lumbar spine (LS) and total hip (thip) as assessed by DXA. After 54 weeks of intervention, borderline nonsignificant intergroup differences were determined for LS-BMD (WB-EMS: 0.6 ± 2.5% versus CG -0.7 ± 2.5%, P = .051) but not for thip-BMD (WB-EMS: -1.1 ± 1.9% versus CG: -0.8 ± 2.3%, P = .771). With respect to secondary endpoints, there was a gain in lean body mass (LBM) of 1.5% (P = .006) and an increase in grip strength of 8.4% (P = .000) in the WB-EMS group compared to CG. WB-EMS effects on bone are less pronounced than previously reported effects on muscle mass. However, for subjects unable or unwilling to perform intense exercise programs, WB-EMS may be an option for maintaining BMD at the LS.

  9. Research on Superimposed Metallogenic System

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    Zhai Yusheng; Wang Jianping; Deng Jun; Peng Runmin

    2004-01-01

    As located in the junction of three tectonic plates (the Eurasian plate, the Indian plate and the west Pacific plate), the China continent shows complex regional metallogenic features due to tectonic evolution of "micro-plates, polycycle tectonic movements". Well developed superimposed metallogenic systems have constituted one of the regional metallogenic features in China. Through the study on superimposed metallogenic system of the middle and lower reaches of the Yangtze River and of the Yuebei basin (northern Guangdong Province), the authors put forward some basic combination pattern of sedimentary-magmatic superimposed metallogenic system and summarize its forming conditions (controlling factors).

  10. Impact of whole-body electromyostimulation on body composition in elderly women at risk for sarcopenia: the Training and ElectroStimulation Trial (TEST-III).

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    Kemmler, Wolfgang; Bebenek, Michael; Engelke, Klaus; von Stengel, Simon

    2014-02-01

    Most studies have confirmed the positive impact of resistance training on muscle mass and functional capacity in aging adults. However, due to physical limitation or a simple aversion against regular exercise, the majority of elderly subjects do not reach the exercise doses recommended for impacting strength or muscle mass. This led us to evaluate the effect of whole-body electromyostimulation (WB-EMS), a novel, time-efficient and smooth training technology, on body composition with special regard to sarcopenia. Seventy-six lean, non-sportive women (75 ± 4 years) were randomly assigned to either a WB-EMS group (WB-EMS, n = 38) that performed 18 min of WB-EMS (bipolar, 85 Hz) 3 sessions in 14 days (1.5 sessions/week) or a semi-active control group (aCG, n = 38). Body composition was assessed by dual-energy X-ray absorptiometry and maximum strength was evaluated using isometric techniques for trunk and legs. After 54 weeks of intervention, significant inter-group differences were determined for appendicular skeletal muscle mass (WB-EMS, 0.4 ± 2.2 % vs. aCG, -1.5 ± 3.1 %; p = 0.009), lean body mass (WB-EMS, 0.8 ± 1.8 % vs. aCG, -0.8 ± 2.7 %; p = 0.008) and maximum isometric strength (leg extensors, 9.8 ± 12.9 % vs. 0.2 ± 10.4 %; p = 0.003; trunk extensors, 10.1 ± 12.7 vs. -1.6 ± 8.6 %; p = 0.001). Although borderline significant for abdominal fat mass (WB-EMS, -2.9 ± 8.3 vs. aCG, 1.5 ± 10.7 %; p = 0.069), differences did not reach statistically significant levels for body fat parameters. Considering the clinical effectiveness for impacting sarcopenia and the good acceptance of this technology by this non-sportive cohort of elderly women, we conclude that for elderly subjects unable or unwilling to perform dynamic strength exercises, electromyostimulation may be a less off-putting alternative to maintain lean body mass and strength.

  11. Effects of Whole-Body Electromyostimulation versus High-Intensity Resistance Exercise on Body Composition and Strength: A Randomized Controlled Study

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    Wolfgang Kemmler

    2016-01-01

    Full Text Available High-intensity (resistance exercise (HIT and whole-body electromyostimulation (WB-EMS are both approaches to realize time-efficient favorable changes of body composition and strength. The purpose of this study was to determine the effectiveness of WB-EMS compared with the gold standard reference HIT, for improving body composition and muscle strength in middle-aged men. Forty-eight healthy untrained men, 30–50 years old, were randomly allocated to either HIT (2 sessions/week or a WB-EMS group (3 sessions/2 weeks that exercised for 16 weeks. HIT was applied as “single-set-to-failure protocol,” while WB-EMS was conducted with intermittent stimulation (6 s WB-EMS, 4 s rest; 85 Hz, 350 ms over 20 minutes. The main outcome parameters were lean body mass (LBM as determined via dual-energy X-ray absorptiometry and maximum dynamic leg-extensor strength (isokinetic leg-press. LBM changes of both groups (HIT 1.25 ± 1.44% versus WB-EMS 0.93±1.15% were significant (p=.001; however, no significant group differences were detected (p=.395. Leg-extensor strength also increased in both groups (HIT 12.7±14.7%, p=.002, versus WB-EMS 7.3±10.3%, p=.012 with no significant (p=.215 between-group difference. Corresponding changes were also determined for body fat and back-extensor strength. Conclusion. In summary, WB-EMS can be considered as a time-efficient but pricy option to HIT-resistance exercise for people aiming at the improvement of general strength and body composition.

  12. Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: the randomized controlled FORMOsA-sarcopenic obesity study

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    Wittmann K

    2016-11-01

    Full Text Available Katharina Wittmann,1 Cornel Sieber,2 Simon von Stengel,1 Matthias Kohl,3 Ellen Freiberger,2 Franz Jakob,4 Michael Lell,5 Klaus Engelke,1 Wolfgang Kemmler1 1Institute of Medical Physics, Faculty of Medicine, Friedrich-Alexander University of Erlangen-Nürnberg, 2Institute for Biomedicine of Aging, Faculty of Medicine, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, 3Faculty of Medical and Life Sciences, University of Furtwangen, 4Musculoskeletal Research Center, University of Würzburg, Würzburg, 5Department of Radiology and Nuclear Medicine, Klinikum Nürnberg, Paracelsus Medizinische Privatuniversität, Nürnberg, Germany Background: Sarcopenic obesity (SO is characterized by a combination of low muscle and high fat mass with an additive negative effect of both conditions on cardiometabolic risk. The aim of the study was to determine the effect of whole-body electromyostimulation (WB-EMS on the metabolic syndrome (MetS in community-dwelling women aged ≥70 years with SO. Methods: The study was conducted in an ambulatory university setting. Seventy-five community-dwelling women aged ≥70 years with SO living in Northern Bavaria, Germany, were randomly allocated to either 6 months of WB-EMS application with (WB-EMS&P or without (WB-EMS dietary supplementation (150 kcal/day, 56% protein or a non-training control group (CG. WB-EMS included one session of 20 min (85 Hz, 350 µs, 4 s of strain–4 s of rest per week with moderate-to-high intensity. The primary study endpoint was the MetS Z-score with the components waist circumference (WC, mean arterial pressure (MAP, triglycerides, fasting plasma glucose, and high-density lipoprotein cholesterol (HDL-C; secondary study endpoints were changes in these determining variables. Results: MetS Z-score decreased in both groups; however, changes compared with the CG were significant (P=0.001 in the WB-EMS&P group only. On analyzing the components of the MetS, significant positive effects

  13. Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: the randomized controlled FORMOsA-sarcopenic obesity study

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    Wittmann, Katharina; Sieber, Cornel; von Stengel, Simon; Kohl, Matthias; Freiberger, Ellen; Jakob, Franz; Lell, Michael; Engelke, Klaus; Kemmler, Wolfgang

    2016-01-01

    Background Sarcopenic obesity (SO) is characterized by a combination of low muscle and high fat mass with an additive negative effect of both conditions on cardiometabolic risk. The aim of the study was to determine the effect of whole-body electromyostimulation (WB-EMS) on the metabolic syndrome (MetS) in community-dwelling women aged ≥70 years with SO. Methods The study was conducted in an ambulatory university setting. Seventy-five community-dwelling women aged ≥70 years with SO living in Northern Bavaria, Germany, were randomly allocated to either 6 months of WB-EMS application with (WB-EMS&P) or without (WB-EMS) dietary supplementation (150 kcal/day, 56% protein) or a non-training control group (CG). WB-EMS included one session of 20 min (85 Hz, 350 μs, 4 s of strain–4 s of rest) per week with moderate-to-high intensity. The primary study endpoint was the MetS Z-score with the components waist circumference (WC), mean arterial pressure (MAP), triglycerides, fasting plasma glucose, and high-density lipoprotein cholesterol (HDL-C); secondary study endpoints were changes in these determining variables. Results MetS Z-score decreased in both groups; however, changes compared with the CG were significant (P=0.001) in the WB-EMS&P group only. On analyzing the components of the MetS, significant positive effects for both WB-EMS groups (P≤0.038) were identified for MAP, while the WB-EMS group significantly differed for WC (P=0.036), and the WB-EMS&P group significantly differed for HDL-C (P=0.006) from the CG. No significant differences were observed between the WB-EMS groups. Conclusion The study clearly confirms the favorable effect of WB-EMS application on the MetS in community-dwelling women aged ≥70 years with SO. However, protein-enriched supplements did not increase effects of WB-EMS alone. In summary, we considered this novel technology an effective and safe method to prevent cardiometabolic risk factors and diseases in older women unable or

  14. Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: the randomized controlled FORMOsA-sarcopenic obesity study.

    Science.gov (United States)

    Wittmann, Katharina; Sieber, Cornel; von Stengel, Simon; Kohl, Matthias; Freiberger, Ellen; Jakob, Franz; Lell, Michael; Engelke, Klaus; Kemmler, Wolfgang

    2016-01-01

    Sarcopenic obesity (SO) is characterized by a combination of low muscle and high fat mass with an additive negative effect of both conditions on cardiometabolic risk. The aim of the study was to determine the effect of whole-body electromyostimulation (WB-EMS) on the metabolic syndrome (MetS) in community-dwelling women aged ≥70 years with SO. The study was conducted in an ambulatory university setting. Seventy-five community-dwelling women aged ≥70 years with SO living in Northern Bavaria, Germany, were randomly allocated to either 6 months of WB-EMS application with (WB-EMS&P) or without (WB-EMS) dietary supplementation (150 kcal/day, 56% protein) or a non-training control group (CG). WB-EMS included one session of 20 min (85 Hz, 350 μs, 4 s of strain-4 s of rest) per week with moderate-to-high intensity. The primary study endpoint was the MetS Z-score with the components waist circumference (WC), mean arterial pressure (MAP), triglycerides, fasting plasma glucose, and high-density lipoprotein cholesterol (HDL-C); secondary study endpoints were changes in these determining variables. MetS Z-score decreased in both groups; however, changes compared with the CG were significant (P=0.001) in the WB-EMS&P group only. On analyzing the components of the MetS, significant positive effects for both WB-EMS groups (P≤0.038) were identified for MAP, while the WB-EMS group significantly differed for WC (P=0.036), and the WB-EMS&P group significantly differed for HDL-C (P=0.006) from the CG. No significant differences were observed between the WB-EMS groups. The study clearly confirms the favorable effect of WB-EMS application on the MetS in community-dwelling women aged ≥70 years with SO. However, protein-enriched supplements did not increase effects of WB-EMS alone. In summary, we considered this novel technology an effective and safe method to prevent cardiometabolic risk factors and diseases in older women unable or unwilling to exercise conventionally.

  15. Whole-body electromyostimulation and protein supplementation favorably affect sarcopenic obesity in community-dwelling older men at risk: the randomized controlled FranSO study

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    Kemmler W

    2017-09-01

    Full Text Available Wolfgang Kemmler,1 Anja Weissenfels,1 Marc Teschler,1 Sebastian Willert,1 Michael Bebenek,1 Mahdieh Shojaa,1 Matthias Kohl,2 Ellen Freiberger,3 Cornel Sieber,3 Simon von Stengel1 1Institute of Medical Physics, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany; 2Faculty of Medical and Life Science, University of Furtwangen, Schwenningen, Germany; 3Institute of Biomedicine of Aging, Friedrich-Alexander University of Erlangen-Nürnberg, Nürnberg, Germany Background: Sarcopenic obesity (SO is a geriatric syndrome characterized by the disproportion between the amount of lean mass and fat mass. Exercise decreases fat and maintains muscle mass; however, older people fail to exercise at doses sufficient to affect musculoskeletal and cardiometabolic risk factors. The aim of this study was to evaluate the effect of whole-body electromyostimulation (WB-EMS, a time-efficient, joint-friendly and highly individualized exercise technology, on sarcopenia and SO in older men. Materials and methods: A total of 100 community-dwelling northern Bavarian men aged ≥70 years with sarcopenia and obesity were randomly (1–1–1 assigned to either 16 weeks of 1 WB-EMS and protein supplementation (WB-EMS&P, 2 isolated protein supplementation or 3 nonintervention control. WB-EMS consisted of 1.5×20 min (85 Hz, 350 µs, 4 s of strain to 4 s of rest applied with moderate-to-high intensity while moving. We further generated a daily protein intake of 1.7–1.8 g/kg/body mass per day. The primary study end point was Sarcopenia Z-Score, and the secondary study end points were body fat rate (%, skeletal muscle mass index (SMI and handgrip strength. Results: Intention-to-treat analysis determined a significantly favorable effect of WB-EMS&P (P<0.001 and protein (P=0.007 vs control. Both groups significantly (P<0.001 lost body fat (WB-EMS&P: 2.1%; protein: 1.1% and differed significantly (P≤0.004 from control (0.3%. Differences between WB-EMS

  16. Whole-body electromyostimulation as a means to impact muscle mass and abdominal body fat in lean, sedentary, older female adults: subanalysis of the TEST-III trial

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    Kemmler W

    2013-10-01

    Full Text Available Wolfgang Kemmler, Simon von StengelInstitute of Medical Physics, University of Erlangen-Nürnberg, Erlangen, GermanyBackground: The primary aim of this study was to determine the effect of 12 months of whole-body electromyostimulation (WB-EMS exercise on appendicular muscle mass and abdominal fat mass in subjects specifically at risk for sarcopenia and abdominal obesity, but unable or unwilling to exercise conventionally.Methods: Forty-six lean, nonsportive (<60 minutes of exercise per week, elderly women (aged 75 ± 4 years with abdominal obesity according to International Diabetes Federation criteria were randomly assigned to either a WB-EMS group (n=23 which performed 18 minutes of intermittent, bipolar WB-EMS (85 Hz three sessions in 14 days or an "active" control group (n=23. Whole-body and regional body composition was assessed by dual energy X-ray absorptiometry to determine appendicular muscle mass, upper leg muscle mass, abdominal fat mass, and upper leg fat mass. Maximum strength of the leg extensors was determined isometrically by force plates.Results: After 12 months, significant intergroup differences were detected for the primary endpoints of appendicular muscle mass (0.5% ± 2.0% for the WB-EMS group versus −0.8% ± 2.0% for the control group, P=0.025 and abdominal fat mass (−1.2% ± 5.9% for the WB-EMS group versus 2.4% ± 5.8% for the control group, P=0.038. Further, upper leg lean muscle mass changed favorably in the WB-EMS group (0.5% ± 2.5% versus −0.9% ± 1.9%, in the control group, P=0.033, while effects for upper leg fat mass were borderline nonsignificant (−0.8% ± 3.5% for the WB-EMS group versus 1.0% ± 2.6% for the control group, P=0.050. With respect to functional parameters, the effects for leg extensor strength were again significant, with more favorable changes in the WB-EMS group (9.1% ± 11.2% versus 1.0% ± 8.1% in the control group, P=0.010.Conclusion: In summary, WB-EMS showed positive effects on the

  17. Statistical properties of superimposed stationary spike trains.

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    Deger, Moritz; Helias, Moritz; Boucsein, Clemens; Rotter, Stefan

    2012-06-01

    The Poisson process is an often employed model for the activity of neuronal populations. It is known, though, that superpositions of realistic, non- Poisson spike trains are not in general Poisson processes, not even for large numbers of superimposed processes. Here we construct superimposed spike trains from intracellular in vivo recordings from rat neocortex neurons and compare their statistics to specific point process models. The constructed superimposed spike trains reveal strong deviations from the Poisson model. We find that superpositions of model spike trains that take the effective refractoriness of the neurons into account yield a much better description. A minimal model of this kind is the Poisson process with dead-time (PPD). For this process, and for superpositions thereof, we obtain analytical expressions for some second-order statistical quantities-like the count variability, inter-spike interval (ISI) variability and ISI correlations-and demonstrate the match with the in vivo data. We conclude that effective refractoriness is the key property that shapes the statistical properties of the superposition spike trains. We present new, efficient algorithms to generate superpositions of PPDs and of gamma processes that can be used to provide more realistic background input in simulations of networks of spiking neurons. Using these generators, we show in simulations that neurons which receive superimposed spike trains as input are highly sensitive for the statistical effects induced by neuronal refractoriness.

  18. Paroxysmal Nocturnal Hemoglobinuria Superimposed with Preeclampsia

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    Mann-Ling Chen

    2006-09-01

    Conclusion: The most frequent causes of PNH-related fetomaternal morbidity and mortality are hemolysis and thrombosis. The situation becomes even more complicated when PNH is superimposed with preeclampsia. Appropriate clinical surveillance, awareness of the potential risks of hemolysis and thrombosis, as well as evaluation of fetal wellbeing are essential.

  19. POWER ALLOCATION OF DATA DEPENDENT SUPERIMPOSED TRAINING

    Institute of Scientific and Technical Information of China (English)

    Wang Ping; Yuan Weina; Fan Pingzhi

    2008-01-01

    Data Dependent Superimposed Training (DDST) scheme outperforms the traditional superimposed training by fully canceling the effects of unknown data in channel estimator. In DDST,however,the channel estimation accuracy and the data detection or channel equalization performance are affected significantly by the amount of power allocated to data and superimposed training sequence,which is the motivation of this research. In general,for DDST,there is a tradeoff between the channel estimation accuracy and the data detection reliability,i.e.,the more accurate the channel estimation,the more reliable the data detection; on the other hand,the more accurate the channel estimation,the more demanding on the power consumption of training sequence,which in turn leads to the less reliable data detection. In this paper,the relationship between the Signal-to-Noise Ratio (SNR) of the data detector and the training sequence power is analyzed. The optimal power allocation of the training sequence is derived based on the criterion of maximizing SNR of the detector. Analysis and simulation results show that for a fixed transmit power,the SNR and the Symbol Error Rate (SER) of detector vary nonlinearly with the increasing of training sequence power,and there exists an optimal power ratio,which accords with the derived optimal power ratio,among the data and training sequence.

  20. Bent Solenoids with Superimposed Dipole Fields

    Energy Technology Data Exchange (ETDEWEB)

    Meinke, Rainer, B.; Goodzeit, Carl, L.

    2000-03-21

    A conceptual design and manufacturing technique were developed for a superconducting bent solenoid magnet with a superimposed dipole field that would be used as a dispersion device in the cooling channel of a future Muon Collider. The considered bent solenoid is equivalent to a 180° section of a toroid with a major radius of ~610 mm and a coil aperture of ~416 mm. The required field components of this magnet are 4 tesla for the solenoid field and 1 tesla for the superimposed dipole field. A magnet of this size and shape, operating at these field levels, has to sustain large Lorentz forces resulting in a maximum magnetic pressure of about 2,000 psi. A flexible round mini-cable with 37 strands of Cu-NbTi was selected as the superconductor. Detailed magnetic analysis showed that it is possible to obtain the required superimposed dipole field by tilting the winding planes of the solenoid by ~25°. A complete structural analysis of the coil support system and the helium containment vessel under thermal, pressure, and Lorentz force loads was carried out using 3D finite element models of the structures. The main technical issues were studied and solutions were worked out so that a highly reliable magnet of this type can be produced at an affordable cost.

  1. Superimposed MRSA infection of vulvar eczematous dermatitis

    Science.gov (United States)

    Carey, Erin; Zedek, Daniel; Lewis, Jasmine; Zolnoun, Denniz

    2014-01-01

    Background Vulvar eczematous dermatitis predisposes patients to superimposed infections, which may result in late diagnosis and architectural destruction. Methicillin resistant staphylococcus aureus (MRSA) infection is on the rise in genitalia and lower extremities. Case 44 year-old female presented with recurrent vulvar lesions and pain. A diagnosis of methicillin resistant staphylococcus aureus in the setting of eczema was achieved with concomitant use of photography and dermatopathologic review. Antibiotics were tailored to the resistant infection and preventative moisturization therapy was utilized. Conclusion Awareness of dermatologic conditions affecting the vulva is principal in routine gynecologic care. Barrier protection of eczematous vulvar skin may prevent superficial infections. The regular use of photographic documentation and dermatopathology may decrease time to diagnosis with infrequent conditions. PMID:23763013

  2. Effect of Superimposed Hydrostatic Pressure on Bendability of Sheet Metals

    Science.gov (United States)

    Chen, X. X.; Wu, P. D.; Lloyd, D. J.

    2010-06-01

    The effect of superimposed hydrostatic pressure on fracture under three-point bending is studied numerically using the finite element method based on the Gurson damage model. It is demonstrated that superimposed hydrostatic pressure significantly increases the bendability and bending fracture strain due to the fact that a superimposed pressure delays or completely eliminates the nucleation, growth and coalescence of microvoids or microcracks. Numerical results are found to be in good agreement with experimental observations.

  3. Could Low-Frequency Electromyostimulation Training be an Effective Alternative to Endurance Training? An Overview in One Adult

    Directory of Open Access Journals (Sweden)

    Gaëlle Deley

    2014-06-01

    Full Text Available This preliminary study aimed to investigate the effects of a six-week low-frequency electromyostimulation training (10Hz on the cardiovascular, respiratory and muscular systems. To that purpose, aerobic capacity, knee extensor muscles strength and architecture, muscle sympathetic nervous activity, blood pressure and heart rate have been evaluated in one healthy male subject (33 year-old, 1.73 m, 73 kg. Results showed improvement of aerobic capacity (+4.5% and +11.5% for maximal oxygen uptake and ventilatory threshold and muscle strength (+11% and +16% for voluntary and evoked force. Moreover, for the first time, this study demonstrated low-frequency training effects on muscle architecture (+3%, +12% and -11% for muscle thickness, pennation angle and fascicle length and cardiovascular parameters (-22%, -18% and -21% for resting muscle sympathetic nervous activity, heart rate and mean blood pressure. Interestingly, these results suggest that this method may have beneficial effects on all systems of the body. The investigation of training effects on muscle architecture and cardiovascular parameters should therefore be pursued since highly deconditioned subjects are likely to fully benefit from these adaptations.

  4. Analyses and Measures of GPR Signal with Superimposed Noise

    Science.gov (United States)

    Chicarella, Simone; Ferrara, Vincenzo; D'Atanasio, Paolo; Frezza, Fabrizio; Pajewski, Lara; Pavoncello, Settimio; Prontera, Santo; Tedeschi, Nicola; Zambotti, Alessandro

    2014-05-01

    The influence of EM noises and environmental hard conditions on the GPR surveys has been examined analytically [1]. In the case of pulse radar GPR, many unwanted signals as stationary clutter, non-stationary clutter, random noise, and time jitter, influence the measurement signal. When GPR is motionless, stationary clutter is the most dominant signal component due to the reflections of static objects different from the investigated target, and to the direct antenna coupling. Moving objects like e.g. persons and vehicles, and the swaying of tree crown, produce non-stationary clutter. Device internal noise and narrowband jamming are e.g. two potential sources of random noises. Finally, trigger instabilities generate random jitter. In order to estimate the effective influence of these noise signal components, we organized some experimental setup of measurement. At first, we evaluated for the case of a GPR basic detection, simpler image processing of radargram. In the future, we foresee experimental measurements for detection of the Doppler frequency changes induced by movements of targets (like physiological movements of survivors under debris). We obtain image processing of radargram by using of GSSI SIR® 2000 GPR system together with the UWB UHF GPR-antenna (SUB-ECHO HBD 300, a model manufactured by Radarteam company). Our work includes both characterization of GPR signal without (or almost without) a superimposed noise, and the effect of jamming originated from the coexistence of a different radio signal. For characterizing GPR signal, we organized a measurement setup that includes the following instruments: mod. FSP 30 spectrum analyser by Rohde & Schwarz which operates in the frequency range 9 KHz - 30 GHz, mod. Sucoflex 104 cable by Huber Suhner (10 MHz - 18 GHz), and HL050 antenna by Rohde & Schwarz (bandwidth: from 850 MHz to 26.5 GHz). The next analysis of superimposed jamming will examine two different signal sources: by a cellular phone and by a

  5. Classification of Complex Reservoirs in Superimposed Basins of Western China

    Institute of Scientific and Technical Information of China (English)

    PANG Xiongqi; ZHOU Xinyuan; LIN Changsong; HUO Zhipeng; LUO Xiaorong; PANG Hong

    2010-01-01

    Many of the sedimentary basins in western China were formed through the superposition and compounding of at least two previously developed sedimentary basins and in general they can be termed as complex superimposed basins.The distinct differences between these basins and monotype basins are their discontinuous stratigraphic sedimentation,stratigraphic structure and stratigraphic stress-strain action over geological history.Based on the correlation of chronological age on structural sections,superimposed basins can be divided into five types in this study:(1)continuous sedimentation type superimposed basins,(2)middle and late stratigraphic superimposed basins,(3)early and late stratigraphic superimposed basins,(4)early and middle stratigraphic superimposed basins,and(5)long-term exposed superimposed basins.Multiple source-reservoir-caprock assemblages have developed in such basins.In addition,multi-stage hydrocarbon generation and expulsion,multiple sources,polycyclic hydrocarbon accumulation and multiple-type hydrocarbon reservoirs adjustment,reformation and destruction have occurred in these basins.The complex reservoirs that have been discovered widely in the superimposed basins to date have remarkably different geologic features from primary reservoirs,and the root causes of this are folding,denudation and the fracture effect caused by multiphase tectonic events in the superimposed basins as well as associated seepage,diffusion,spilling,oxidation,degradation and cracking.Based on their genesis characteristics,complex reservoirs are divided into five categories:(1)primary reservoirs,(2)trap adjustment type reservoirs,(3)component variant reservoirs,(4)phase conversion type reservoirs and(5)scale-reformed reservoirs.

  6. Angiosarcoma of the Eyelid With Superimposed Enterobacter Infection.

    Science.gov (United States)

    Hamill, Eric B; Agrawal, Megha; Diwan, A Hafeez; Winthrop, Kevin L; Marx, Douglas P

    2016-01-01

    Angiosarcoma is a rare, aggressive, malignant endothelial neoplasm with a variable clinical presentation. The authors describe a case of angiosarcoma involving the eyelid that was complicated by a superimposed Enterobacter infection. Following positive cultures for E. aerogenes and multiple biopsies suspicious but not definitive for angiosarcoma, a final biopsy was consistent with angiosarcoma.

  7. Tools to Detect Delirium Superimposed on Dementia: A Systematic Review

    Science.gov (United States)

    Morandi, Alessandro; McCurley, Jessica; Vasilevskis, Eduard E.; Fick, Donna M.; Bellelli, Giuseppe; Lee, Patricia; Jackson, James C.; Shenkin, Susan D.; Trabucchi, Marco; Schnelle, John; Inouye, Sharon K.; Ely, Wesley E.; MacLullich, Alasdair

    2012-01-01

    Background Delirium commonly occurs in patients with dementia. Though several tools for detecting delirium exist, it is unclear which are valid in patients with delirium superimposed on dementia. Objectives Identify valid tools to diagnose delirium superimposed on dementia Design We performed a systematic review of studies of delirium tools, which explicitly included patients with dementia. Setting In-hospital patients Participants Studies were included if delirium assessment tools were validated against standard criteria, and the presence of dementia was assessed according to standard criteria that used validated instruments. Measurements PubMed, Embase, and Web of Science databases were searched for articles in English published between January 1960 and January 2012. Results Nine studies fulfilled the selection criteria. Of the total of 1569 patients, 401 had dementia, and 50 had delirium superimposed on dementia. Six delirium tools were evaluated. One studyusing the Confusion Assessment Method (CAM) with 85% patients with dementia showed a high specificity (96–100%) and moderate sensitivity (77%).Two intensive care unit studies that used the CAM for the Intensive Care Unit (CAM-ICU) ICU reported 100% sensitivity and specificity for delirium among 23 dementia patients. One study using electroencephalography reported a sensitivity of 67% and a specificity of 91% among a population with 100% prevalence of dementia. No studies examined potential effects of dementia severity or subtype upon diagnostic accuracy. Conclusions The evidence base on tools for detection of delirium superimposed on dementia is limited, although some existing tools show promise. Further studies of existing or refined tools with larger samples and more detailed characterization of dementia are now required to address the identification of delirium superimposed on dementia. PMID:23039270

  8. Shear flow analyses for polymer melt extruding under superimposed vibration

    Institute of Scientific and Technical Information of China (English)

    LIU Yue-jun; FAN Shu-hong; SHI Pu

    2005-01-01

    The introduction of a vibration force field has a profound influence on the polymer formation process.However, its formation mechanism has not been explored until now. With the application of experimental equipment designed by the authors named "Constant Velocity Type Dynamic Rheometer of Capillary" or (CVDRC),we were able to analyze in detail the whole extrusion process of a polymer melt. We did this after superimposing a sine vibration of small amplitude parallel to the extruding direction of the polymer melt. Then, we created a calculation model to determine the shear stress at the wall of the capillary using a superimposed vibration. We also determined the calculation steps needed to establish the afore-mentioned shear stress. Through measurement and analysis, the instantaneous entry pressure of the capillary, the pressure gradient, and the shear stress of the polymer melt within the capillary under vibration force field can be calculated.

  9. Artistic creation as stimulated by superimposed versus separated visual images.

    Science.gov (United States)

    Sobel, R S; Rothenberg, A

    1980-11-01

    An experiment was performed to examine the role of homospatial thinking in visual art. Each of 43 university-level art students produced three drawing stimulated by pairs of slides. Subjects were randomly assigned to view the pairs either superimposed on one another or separated on the screen. Drawings were independently judged by two internationally noted artists. As predicted, drawings containing an element from each component image intermingled were higher in creative potential when stimulated by the superimposed presentation; however, when sketches from either condition did not clearly contain images from both slides, the separated image presentation yielded the more creative result. Although results favor the hypothesis in part, the overall ambiguity of the data illustrates some of the difficulties in studying creative thought processes under experimental conditions.

  10. One-DOF Superimposed Rigid Origami with Multiple States

    OpenAIRE

    Xiang Liu; Gattas, Joseph M.; Yan Chen

    2016-01-01

    Origami-inspired engineering design is increasingly used in the development of self-folding structures. The majority of existing self-folding structures either use a bespoke crease pattern to form a single structure, or a universal crease pattern capable of forming numerous structures with multiple folding steps. This paper presents a new approach whereby multiple distinct, rigid-foldable crease patterns are superimposed in the same sheet such that kinematic independence and 1-DOF mobility of...

  11. Recrystallization microstructure modelling from superimposed deformed microstructure on microstructure model

    Indian Academy of Sciences (India)

    Prantik Mukhopadhyay

    2009-08-01

    The recovered cold rolled microstructure obtained from orientation image microstructure of Al–4%Mg–0.5%Mn alloy (AA5182 alloy) was superimposed on the grid of cellular automata based microstructure model. The Taylor factors of deformed/cold rolled orientations were considered as the driving force for recrystallization. The local development of recrystallized microstructure and texture were simulated with orientation dependent grain boundary mobility and compared with the experimental results.

  12. Ballistic annihilation with superimposed diffusion in one dimension.

    Science.gov (United States)

    Biswas, Soham; Larralde, Hernán; Leyvraz, Francois

    2016-02-01

    We consider a one-dimensional system with particles having either positive or negative velocity, and these particles annihilate on contact. Diffusion is superimposed on the ballistic motion of the particle. The annihilation may represent a reaction in which the two particles yield an inert species. This model has been the subject of previous work, in which it was shown that the particle concentration decays faster than either the purely ballistic or the purely diffusive case. We report on previously unnoticed behavior for large times when only one of the two species remains, and we also unravel the underlying fractal structure present in the system. We also consider in detail the case in which the initial concentration of right-going particles is 1/2+ɛ, with ɛ≠0. It is shown that remarkably rich behavior arises, in which two crossover times are observed as ɛ→0.

  13. One-DOF Superimposed Rigid Origami with Multiple States

    Science.gov (United States)

    Liu, Xiang; Gattas, Joseph M.; Chen, Yan

    2016-11-01

    Origami-inspired engineering design is increasingly used in the development of self-folding structures. The majority of existing self-folding structures either use a bespoke crease pattern to form a single structure, or a universal crease pattern capable of forming numerous structures with multiple folding steps. This paper presents a new approach whereby multiple distinct, rigid-foldable crease patterns are superimposed in the same sheet such that kinematic independence and 1-DOF mobility of each individual pattern is preserved. This is enabled by the cross-crease vertex, a special configuration consisting of two pairs of collinear crease lines, which is proven here by means of a kinematic analysis to contain two independent 1-DOF rigid-foldable states. This enables many new origami-inspired engineering design possibilities, with two explored in depth: the compact folding of non-flat-foldable structures and sequent folding origami that can transform between multiple states without unfolding.

  14. Electronically reconfigurable superimposed waveguide long-period gratings

    Science.gov (United States)

    Kulishov, Mykola; Daxhelet, Xavier; Gaidi, Mounir; Chaker, Mohamed

    2002-08-01

    The perturbation to the refractive index induced by a periodic electric field from two systems of interdigitated electrodes with the electrode-finger period l is analyzed for a waveguide with an electro-optically (EO) active core-cladding. It is shown that the electric field induces two superimposed transmissive refractive-index gratings with different symmetries of their cross-section distributions. One of these gratings has a constant component of an EO-induced refractive index along with its variable component with periodicity l, whereas the second grating possesses only a variable component with periodicity 2l. With the proper waveguide design, the gratings provide interaction between a guided fundamental core mode and two guided cladding modes. Through the externally applied electric potential, these gratings can be independently switched ON and OFF, or they can be activated simultaneously with electronically controlled weighting factors. Coupling coefficients of both gratings are analyzed in terms of their dependence on the electrode duty ratio and dielectric permittivities of the core and cladding. The coupled-wave equations for the superimposed gratings are written and solved. The spectral characteristics are investigated by numerical simulation. It is found that the spectral characteristics are described by a dual-dip transmission spectrum with individual electronic control of the dip depths and positions. Within the concept, a new external potential application scheme is described in which the symmetry of the cross-sectional distribution of the refractive index provides coupling only between the core mode and the cladding modes, preventing interaction of the cladding modes with each another. This simple concept opens opportunities for developing a number of tunable devices for integrated optics by use of the proposed design as a building block.

  15. Nursing care for people with delirium superimposed on dementia.

    Science.gov (United States)

    Pryor, Claire; Clarke, Amanda

    2017-03-31

    Nursing and healthcare is changing in response to an ageing population. There is a renewed need for holistic nursing to provide clinically competent, appropriate and timely care for patients who may present with inextricably linked mental and physical health requirements. This article explores the dichotomy in healthcare provision for 'physical' and 'mental' health, and the unique role nurses have when caring for people with delirium superimposed on dementia (DSD). Delirium is prevalent in older people and recognised as 'acute brain failure'. As an acute change in cognition, it presents a unique challenge when occurring in a person with dementia and poses a significant risk of mortality. In this article, dementia is contrasted with delirium and subtypes of delirium presentation are discussed. Nurses can recognise DSD through history gathering, implementation of appropriate care and effective communication with families and the multidisciplinary team. A simple mnemonic called PINCH ME (Pain, INfection, Constipation, deHydration, Medication, Environment) can help identify potential underlying causes of DSD and considerations for care planning. The mnemonic can easily be adapted to different clinical settings and a fictitious scenario is presented to show its application in practice.

  16. Bilateral effects of unilateral electromyostimulation training on strength and surface myoelectric signal%单侧肢体电刺激训练对双侧肢体力量和表面肌电的影响

    Institute of Scientific and Technical Information of China (English)

    于俊海; 周石; 黄力平

    2013-01-01

    目的:运用表面肌电技术观察单侧肢体电刺激训练对双侧肢体力量和表面肌电(sEMG)的影响,为临床单侧肢体损伤、外科术后等引起的肌萎缩的康复治疗以及建立床边客观的训练效果评定方法提供依据.方法:选择18-30岁未经专项体育训练的青年男性30例为实验对象,随机分为电刺激组,随意等长收缩组和对照组.采用重复等长收缩模式对右侧胫骨前肌进行6周的电刺激和随意力量训练.训练前后进行双侧肌肉力量和sEMG测试.结果:电刺激组(右33.6%,左27.8%)和随意等长收缩组(右37.4%,左28.5%)训练侧和未训练侧的足背屈肌肉力量在训练后均有显著提高,与对照组(右1.3%,左0.8%)有显著性差异(P<0.05);随意等长收缩组(右100.4%,左59.4%)与电刺激组(右68.1%,左57.7%)双侧肌电平均振幅(AEMG)均有明显变化,并与对照组(右5.04%,左-4.07%)有显著性差异(P<0.05);肌肉不同等长用力和肌电振幅之间表现出非线性的关系,以指数y=43.762(9.584)分布.结论:6周单侧肢体电刺激训练和随意等长收缩训练不仅能够明显的提高训练侧的肢体力量,亦能提高对侧未受训练肢体的肌肉力量;训练导致的力量增长与使用表面肌电观察到的AEMG的变化有关;肌肉力量和肌电振幅之间表现出非线性的关系,可以利用肌电振幅与相对力量的关系(y=43.762(9.584)',在力量测试中评估受试者的用力程度,为临床康复训练提供理论依据和测试评价手段.%Objective: To investigate the bilateral effects of unilateral electromyostimulation (EMS) training on muscle strength and surface myoelectric signal by surface electro myogram(sEMG) technique. Method: Thirty healthy male volunteers, aged 18-30 years, were randomly assigned into three groups (n=10 each): EMS group, voluntary isometric contraction (VIM) group, and control (CON) group. The patients of EMS and VIM groups were

  17. Risk Factors of Superimposed Preeclampsia in Women with Essential Chronic Hypertension Treated before Pregnancy

    OpenAIRE

    2013-01-01

    OBJECTIVE: To determine risk factors of superimposed preeclampsia in women with essential chronic hypertension receiving antihypertensive therapy prior to conception. METHODS: A retrospective study of 211 patients that analyzed risk factors of superimposed preeclampsia at first prenatal visit. Variables with a p

  18. 16 CFR 300.27 - Wool products containing superimposed or added fibers.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Wool products containing superimposed or added fibers. 300.27 Section 300.27 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE WOOL PRODUCTS LABELING ACT OF 1939 Labeling § 300.27 Wool products containing superimposed...

  19. EFFECTS OF COMBINED FOOT/ANKLE ELECTROMYOSTIMULATION AND RESISTANCE TRAINING ON THE IN-SHOE PLANTAR PRESSURE PATTERNS DURING SPRINT IN YOUNG ATHLETES

    Directory of Open Access Journals (Sweden)

    François Fourchet

    2011-06-01

    Full Text Available Several studies have already reported that specific foot/ankle muscle reinforcement strategies induced strength and joint position sense performance enhancement. Nevertheless the effects of such protocols on sprint performance and plantar loading distribution have not been addressed yet. The objective of the study is to investigate the influence of a 5-wk foot/ankle strength training program on plantar loading characteristics during sprinting in adolescent males. Sixteen adolescent male athletes of a national training academy were randomly assigned to either a combined foot/ankle electromyostimulation and resistance training (FAST or a control (C group. FAST consisted of foot medial arch and extrinsic ankle muscles reinforcement exercises, whereas C maintained their usual training routine. Before and after training, in-shoe loading patterns were measured during 30-m running sprints using pressure sensitive insoles (right foot and divided into nine regions for analysis. Although sprint times remained unchanged in both groups from pre- to post- training (3.90 ± 0.32 vs. 3.98 ± 0.46 s in FAST and 3.83 ± 0.42 vs. 3.81 ± 0.44 s in C, changes in force and pressure appeared from heel to forefoot between FAST and C. In FAST, mean pressure and force increased in the lateral heel area from pre- to post- training (67.1 ± 44.1 vs. 82.9 ± 28.6 kPa [p = 0.06]; 25.5 ± 17.8 vs. 34.1 ± 14.3 N [p = 0.05] and did not change in the medial forefoot (151.0 ± 23.2 vs. 146.1 ± 30.0 kPa; 142.1 ± 29.4 vs. 136.0 ± 33.8; NS. Mean area increased in FAST under the lateral heel from pre- to post- (4.5 ± 1.3 vs. 5.7 ± 1.6 cm2 [p < 0.05] and remained unchanged in C (5.5 ± 2.8 vs. 5.0 ± 3.0 cm2. FAST program induced significant promising lateral and unwanted posterior transfer of the plantar loads without affecting significantly sprinting performance

  20. Angiogenic factors in superimposed preeclampsia: a longitudinal study of women with chronic hypertension during pregnancy.

    Science.gov (United States)

    Perni, Uma; Sison, Cristina; Sharma, Vijay; Helseth, Geri; Hawfield, Amret; Suthanthiran, Manikkam; August, Phyllis

    2012-03-01

    Imbalances in circulating angiogenic factors contribute to the pathogenesis of preeclampsia. To characterize levels of angiogenic factors in pregnant women with chronic hypertension, we prospectively followed 109 women and measured soluble fms-like tyrosine kinase 1 (sFlt1), soluble endoglin, and placental growth factor at 12, 20, 28, and 36 weeks' gestation and postpartum. Superimposed preeclampsia developed in 37 (34%) and was early onset (hypertension. We conclude that alterations in angiogenic factors are detectable before and at the time of clinical diagnosis of early onset superimposed preeclampsia, whereas alterations were observed only at the time of diagnosis in women with late-onset superimposed preeclampsia. Longitudinal measurements of angiogenic factors may help anticipate early onset superimposed preeclampsia and facilitate diagnosis of superimposed preeclampsia in women with chronic hypertension.

  1. Monitoring of vacuum assisted resin transfer moulding (VARTM) process with superimposed Fiber-Bragg-gratings

    Science.gov (United States)

    Triollet, S.; Robert, L.; Marin, E.; Ouerdane, Y.

    2011-05-01

    We report the instrumentation of a manufacturing composite process using an optical fiber sensor based on Bragg gratings. The sensor is made of superimposed Long Period (LPG) and short period (FBG) Bragg gratings written in the same fiber section. The monitoring of the process needs simultaneous measurements of temperature and strain. It has been shown that these two solicitations can be determined and discriminated with a superimposed FBG/LPG sensor [1]. In this paper we present the device based on the dual superimposed gratings. The sensor is embedded in a composite specimen manufactured by Vacuum Assisted Resin Transfer Moulding (VARTM) process for monitoring purpose.

  2. Comparative Analysis of Sequence Characteristics among Different Superimposed Stages of the Chelif Basin, Algeria

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yuanfu; JIANG Zaixing; WANG Yue; BAO Dandan

    2009-01-01

    Superimposed basins were investigated with respect to tectonic evolution, sediment deposition and petroleum characteristics within a single superposition stage generally. The comparative study was seldom seen. Sequence characteristics were compared for two different superimposed stages-an expanding rifting stage and a depression-foreland transition stage-in the Chelif Basin during the Miocene in this paper. A model and mechanism for sequence evolution of superimposed basins in different dynamic situations are discussed with respect to sequence similarities and differences. The compared characters include sequence thickness, sequence boundaries and system tracts, as well as sediment deposition within sequences and sequence development patterns. Finally, some typical features of sequence development concomitant with changes of superimposed stages in the Chelif Basin are discussed.

  3. Superimposing of virtual graphics and real image based on 3D CAD information

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Proposes methods of transforming 3D CAD models into 2D graphics and recognizing 3D objects by features and superimposing VE built in computer onto real image taken by a CCD camera, and presents computer simulation results.

  4. Glucose clearance in aged trained skeletal muscle during maximal insulin with superimposed exercise

    DEFF Research Database (Denmark)

    Dela, Flemming; Mikines, K J; Larsen, J J

    1999-01-01

    clamp with a final 30 min of superimposed two-legged exercise at 70% of individual maximal heart rate. With superimposed exercise, leg glucose extraction decreased (P exercise, leg......Insulin and muscle contractions are major stimuli for glucose uptake in skeletal muscle and have in young healthy people been shown to be additive. We studied the effect of superimposed exercise during a maximal insulin stimulus on glucose uptake and clearance in trained (T) (1-legged bicycle...... +/- 8, DM: 70 +/- 10 ml. min(-1). kg leg(-1)) compared with UT (H: 63 +/- 8, DM: 45 +/- 7 ml. min(-1). kg leg(-1)) but not different between groups (P > 0.05). From these results it can be concluded that, in both diabetic and healthy aged muscle, exercise adds to a maximally insulin-stimulated glucose...

  5. Observations of superimposed ice formation at melt-onset on fast ice on Kongsfjorden, Svalbard

    OpenAIRE

    Nicolaus, Marcel; Haas, Christian; Bareiss, Jörg

    2003-01-01

    Measurements of superimposed ice formation and snow properties as a function of the surface energy balance during melt-onset are presented. They were performed on Kongsfjorden, Svalbard, between late May and early June 2002. Rapid snow melt commenced and within 5 days the snow cover initially 0.23 m thick transformed completely into 0.05 m to 0.06 m of superimposed ice. Melt-onset was characterized by rapid changes in the total energy balance, which became positive throughout the whole day af...

  6. 16 CFR 303.23 - Textile fiber products containing superimposed or added fibers.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Textile fiber products containing... UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE TEXTILE FIBER PRODUCTS IDENTIFICATION ACT § 303.23 Textile fiber products containing superimposed or added fibers. Where a textile...

  7. Chronic hypertension superimposed on preeclampsia at 13 gestational weeks: a case report with review

    Institute of Scientific and Technical Information of China (English)

    ZHU Yu-chun; SUN Yu; YANG Hui-xia

    2012-01-01

    Preeclampsia is represented by hypertension and proteinuria in pregnancy.It usually occurs after 20 gestational weeks.There are few reports on preeclampsia before 20 gestational weeks.In this case,we report a patient with chronic hypertension superimposed with preeclampsia at 13 gestational weeks.

  8. A Teething Problem: Artefactual X-Ray Appearances of Odontoid Fracture due to Superimposed Incisor

    Directory of Open Access Journals (Sweden)

    Matthew Crocker

    2012-01-01

    Full Text Available We report a case of artefactual C2 fracture caused by a superimposed incisor tooth in a seven-year-old boy. CT refuted the diagnosis. Trauma clinicians should be aware of this entity to guide correct interpretation of trauma X-rays.

  9. Superimposed Pilots Are Superior for Mitigating Pilot Contamination in Massive MIMO

    Science.gov (United States)

    Upadhya, Karthik; Vorobyov, Sergiy A.; Vehkapera, Mikko

    2017-06-01

    In this paper, superimposed pilots are introduced as an alternative to time-multiplexed pilot and data symbols for mitigating pilot contamination in massive multiple-input multiple-output (MIMO) systems. We propose a non-iterative scheme for uplink channel estimation based on superimposed pilots and derive an expression for the uplink signal-to-interference-plus-noise ratio (SINR) at the output of a matched filter employing this channel estimate. Based on this expression, we observe that power control is essential when superimposed pilots are employed. Moreover, the quality of the channel estimate can be improved by reducing the interference that results from transmitting data alongside the pilots, and an intuitive iterative data-aided scheme that reduces this component of interference is also proposed. Approximate expressions for the uplink SINR are provided for the iterative data-aided method as well. In addition, we show that a hybrid system with users utilizing both time-multiplexed and superimposed pilots is superior to an optimally designed system that employs only time-multiplexed pilots, even when the non-iterative channel estimate is used to build the detector and precoder. We also describe a simple approach to implement this hybrid system by minimizing the overall inter and intra-cell interference. Numerical simulations demonstrating the performance of the proposed channel estimation schemes and the superiority of the hybrid system are also provided.

  10. Randomization of Symbol Repetition of Punch Cards with Superimposed Coding in Information-Search Systems.

    Science.gov (United States)

    Pirovich, L. Ya

    The article shows the effect of the irregularity of using separate symbols on search noise on punch cards with superimposed symbol coding in information-search system (IPS). A binomial law of random value distribution of repetition of each symbol is established and analyzed. A method of determining the maximum value of symbol repetition is…

  11. Late-Stage Reservoir Formation Effect and Its Dynamic Mechanisms in Complex Superimposed Basins

    Institute of Scientific and Technical Information of China (English)

    KANG Dejiang; PANG Xiongqi; KUANG Jun; LUO Xiaorong; PANG Hong; LEI Lei

    2010-01-01

    Complex superimposed basins exhibit multi-stage tectonic events and multi-stage reservoir formation; hydrocarbon reservoirs formed in the early stage have generally late-stage genesis characteristics after undergoing adjustment,reconstruction and destruction of later-stage multiple tectonic events.In this paper,this phenomenon is called the late-stage reservoir formation effect.The late-stage reservoir formation effect is a basic feature of oil and gas-forming reservoirs in complex superimposed basins,revealing not only multi-stage character,relevance and complexity of oil and gas-forming reservoirs in superimposed basins but also the importance of late-stage reservoir formation.Late-stage reservoir formation is not a basic feature of off and gas forming reservoir in superimposed basins.Multi-stage reservoir formation only characterizes one aspect of oil and gas-forming reservoir in superimposed basins and does not represent fully the complexity of oil and gas-forming reservoir in superimposed basins.We suggest using"late-stage reservoir formation effect"to replace the"late-stage reservoir formation"concept to guide the exploration of complex reservoirs in superimposed basins.Under current geologic conditions,the late-stage reservoir formation effect is represented mainly by four basic forms:phase transformation,scale reconstruction,component variation and trap adjustment.The late-stage reservoir formation effect is produced by two kinds of geologic processes:first,the off and gas retention function of various geologic thresholds(hydrocarbon expulsion threshold,hydrocarbon migration threshold,and hydrocarbon accumulating threshold)causes the actual time of oil and gas reservoir formation to be later than the time of generation of large amounts of hydrocarbon in a conventional sense,producing the late-stage reservoir formation effect; second,multiple types of tectonic events(continuously strong reconstruction,early-stage strong reconstruction,middle-stage strong

  12. Demonstrating Chirality: Using a Mirror with Physical Models To Show Non-superimposability of Chiral Molecules with Their Mirror Images.

    Science.gov (United States)

    Collins, Michael J.

    2001-01-01

    Presents a remarkable demonstration on chiralty in molecules and the existence of enantiomers, also known as non-superimposable mirror images. Uses a mirror, a physical model of a molecule, and a bit of trickery involving the non-superimposable mirror image. (Author/NB)

  13. A 10-days heatwave around flowering superimposed on climate change conditions significantly affects production of 22 barley accessions

    DEFF Research Database (Denmark)

    Ingvordsen, Cathrine Heinz; Lyngkjær, Michael F.; Peltonen-Sainio, Pirjo;

    2015-01-01

    representing a worst case scenario (~RCP8.5, IPCC) at the end of the 21st century. A 10 day-heatwave of 33/22°C (day/night) was superimposed around the time of flowering on the basic climate treatments. The superimposed heatwave decreased overall grain yield in all combinations, however, vast variation...

  14. Detection of correlated fragments in a sequence of images by superimposed Fourier holograms

    Science.gov (United States)

    Pavlov, A. V.

    2016-08-01

    The problem of detecting correlated fragments in a sequence of images recorded by the superimposing holograms within the Fourier holography scheme with angular multiplication of a spatially modulated reference beam is considered. The approach to the solution of this problem is based on the properties of the variance of the image sum. It is shown that this problem can be solved by providing a constant distance between the signal and reference images when recording superimposed holograms and a partial mutual correlatedness of reference images. The detection efficiency is analysed from the point of view of estimated image data capacity, the degree of mutual correlation of reference images, and the hologram recording conditions. The results of a numerical experiment under the most complicated conditions (representation of images by realisations of homogeneous random fields) confirm the theoretical conclusions.

  15. Artistic creation as stimulated by superimposed versus combined-composite visual images.

    Science.gov (United States)

    Rothenberg, A

    1986-02-01

    The creative role of homospatial thinking in visual art was assessed in an experiment with 39 highly talented young artists. In order to compare the creative effects of visual elements occupying the same space with identical elements arrayed in a combined foreground and background organization, superimposed slide images were presented to a randomly selected portion of the subject group, and the other portion of the subject group viewed the same slide images constructed into a figure-ground composite. Both groups produced three drawings stimulated by the slide stimuli, and these drawings were independently judged by three art experts. Results were that drawings produced by the group exposed to the superimposed images were rated higher in creative potential than those stimulated by the figure-ground controls. These results extend previous experimental findings of a tendency toward homospatial thinking in creative individuals in literature and visual art.

  16. Multiple-Element Matching Reservoir Formation and Quantitative Prediction of Favorable Areas in Superimposed Basins

    Institute of Scientific and Technical Information of China (English)

    WANG Huaijie; PANG Xiongqi; WANG Zhaoming; YU Qiuhua; HUO Zhipeng; MENG Qingyang

    2010-01-01

    Superimposed basins in West China have experienced multi-stage tectonic events and multicycle hydrocarbon reservoir formation,and complex hydrocarbon reservoirs have been discovered widely in basins of this kind.Most of the complex hydrocarbon reservoirs are characterized by relocation,scale re-construction,component variation and phase state transformation,and their distributions are very difficult to predict.Research shows that regional caprock(C),high-quality sedimentary facies(Deposits,D),paleohighs(Mountain,M)and source rock(S)are four geologic elements contributing to complex hydrocarbon reservoir formation and distribution of western superimposed basins.Longitudinal sequential combinations of the four elements control the strata of hydrocarbon reservoir formation,and planar superimpositions and combinations control the range of hydrocarbon reservoir and their simultaneous joint effects in geohistory determine the time of hydrocarbon reservoir formation.Multiple-element matching reservoir formation presents a basic mode of reservoir formation in superimposed basins,and we recommend it is expressed as T-CDMS.Based on the multiple-element matching reservoir formation mode,a comprehensive reservoir formation index(Tcdms)is developed in this paper to characterize reservoir formation conditions,and a method is presented to predict reservoir formation range and probability of occurrence in superimposed basins.Through application of new theory,methods and technology,the favorable reservoir formation range and probability of occurrence in the Ordovician target zone in Tarim Basin in four different reservoir formation periods are predicted.Results show that central Tarim,Yinmaili and Lunnan are the three most favorable regions where Ordovician oil and gas fields may have formed.The coincidence of prediction results with currently discovered hydrocarbon reservoirs reaches 97%.This reflects the effectiveness and reliability of the new theory,methods and technology.

  17. Plasma cortisol levels in malnourished children with and without superimposed acute stress

    Science.gov (United States)

    Paisey, R. B.; Angers, Marielena; Frenk, S.

    1973-01-01

    Plasma cortisol levels were measured in 13 children with marasmus, in 7 with kwashiorkor, and in 24 normal children. Cortisol levels in the malnourished children did not differ from those of the normal group, either before or after 15 or 30 days of treatment, unless there was superimposed acute stress. Stress caused by complications such as hypoglycaemia, infection, hypothermia, or acidosis led to raised plasma cortisol levels. PMID:4733640

  18. Superimposed electrical stimulation comfortably improves the endurance of maximal voluntary contractions.

    OpenAIRE

    Boisgontier, Matthieu; Moineau, Bastien; Nougier, Vincent

    2012-01-01

    International audience; AIM: Electrical stimulation has shown to improve muscle endurance in sub-maximal contractions but sessions were painful due to the electric stimuli parameters. Therefore, the present study tested the effects of the superimposed electrical stimulation technique using comfortable current on endurance in repetitions of maximal voluntary contraction. METHODS: Seventeen young healthy subjects performed fifty maximal voluntary contractions of the triceps brachii in two condi...

  19. Linearly Time-Varying Channel Estimation and Symbol Detection for OFDMA Uplink Using Superimposed Training

    Directory of Open Access Journals (Sweden)

    Zhang Han

    2009-01-01

    Full Text Available We address the problem of superimposed trainings- (STs- based linearly time-varying (LTV channel estimation and symbol detection for orthogonal frequency-division multiplexing access (OFDMA systems at the uplink receiver. The LTV channel coefficients are modeled by truncated discrete Fourier bases (DFBs. By judiciously designing the superimposed pilot symbols, we estimate the LTV channel transfer functions over the whole frequency band by using a weighted average procedure, thereby providing validity for adaptive resource allocation. We also present a performance analysis of the channel estimation approach to derive a closed-form expression for the channel estimation variances. In addition, an iterative symbol detector is presented to mitigate the superimposed training effects on information sequence recovery. By the iterative mitigation procedure, the demodulator achieves a considerable gain in signal-interference ratio and exhibits a nearly indistinguishable symbol error rate (SER performance from that of frequency-division multiplexed trainings. Compared to existing frequency-division multiplexed training schemes, the proposed algorithm does not entail any additional bandwidth while with the advantage for system adaptive resource allocation.

  20. Nitrogen washout during tidal breathing with superimposed high-frequency chest wall oscillation.

    Science.gov (United States)

    Harf, A; Zidulka, A; Chang, H K

    1985-08-01

    In order to assess the efficacy of high-frequency chest wall oscillation (HFCWO) superimposed on tidal ventilation, multiple-breath nitrogen washout curves were obtained in 7 normal seated subjects. To maintain a regular breathing pattern throughout the study, the subjects breathed synchronously with a Harvard ventilator set at a constant tidal volume and frequency for each subject during a trial period. Washout curves were obtained during 3 different maneuvers performed in random order. Series A was the control condition with no superimposed HFCWO. In Series B and C, HFCWO at 5 Hz was superimposed on the regulated tidal breathing; the magnitude of the oscillatory tidal volume measured at the airway opening was 20 ml for Series B and 40 ml for Series C. The nitrogen washout was clearly faster in Series C than in Series A for each subject. In Series B, there was an interindividual variability, with a washout rate either equal to that in Maneuver A or in Maneuver C, or intermediate between the two. When these washout curves were analyzed in terms of a simple monocompartment model, the time constant of the washout was found to decrease by 16 +/- 11% in Series B, and 25 +/- 7% in Series C compared with that in Series A. In this group of normal subjects, the correction of any inhomogeneity in the distribution of the ventilation is unlikely to explain these results because of the close fit of all washout curves to a monoexponential model. It is postulated that during inspiration HFCWO enhances gas mixing in the lung periphery and that during expiration it improves gas mixing in the airways.(ABSTRACT TRUNCATED AT 250 WORDS)

  1. Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial

    Directory of Open Access Journals (Sweden)

    E.V. Souza

    2014-05-01

    Full Text Available Preeclampsia is an important cause of maternal and perinatal morbidity and mortality. Previous studies have tested calcium supplementation and aspirin separately to reduce the incidence of preeclampsia but not the effects of combined supplementation. The objective of this study was to investigate the effectiveness of aspirin combined with calcium supplementation to prevent preeclampsia in women with chronic hypertension. A double-blind, placebo-controlled randomized clinical trial was carried out at the antenatal clinic of a large university hospital in São Paulo, SP, Brazil. A total of 49 women with chronic hypertension and abnormal uterine artery Doppler at 20-27 weeks gestation were randomly assigned to receive placebo (N = 26 or 100 mg aspirin plus 2 g calcium (N = 23 daily until delivery. The main outcome of this pilot study was development of superimposed preeclampsia. Secondary outcomes were fetal growth restriction and preterm birth. The rate of superimposed preeclampsia was 28.6% lower among women receiving aspirin plus calcium than in the placebo group (52.2 vs 73.1%, respectively, P=0.112. The rate of fetal growth restriction was reduced by 80.8% in the supplemented group (25 vs 4.8% in the placebo vs supplemented groups, respectively; P=0.073. The rate of preterm birth was 33.3% in both groups. The combined supplementation of aspirin and calcium starting at 20-27 weeks of gestation produced a nonsignificant decrease in the incidence of superimposed preeclampsia and fetal growth restriction in hypertensive women with abnormal uterine artery Doppler.

  2. Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial.

    Science.gov (United States)

    Souza, E V; Torloni, M R; Atallah, A N; Santos, G M S dos; Kulay, L; Sass, N

    2014-05-01

    Preeclampsia is an important cause of maternal and perinatal morbidity and mortality. Previous studies have tested calcium supplementation and aspirin separately to reduce the incidence of preeclampsia but not the effects of combined supplementation. The objective of this study was to investigate the effectiveness of aspirin combined with calcium supplementation to prevent preeclampsia in women with chronic hypertension. A double-blind, placebo-controlled randomized clinical trial was carried out at the antenatal clinic of a large university hospital in São Paulo, SP, Brazil. A total of 49 women with chronic hypertension and abnormal uterine artery Doppler at 20-27 weeks gestation were randomly assigned to receive placebo (N = 26) or 100 mg aspirin plus 2 g calcium (N = 23) daily until delivery. The main outcome of this pilot study was development of superimposed preeclampsia. Secondary outcomes were fetal growth restriction and preterm birth. The rate of superimposed preeclampsia was 28.6% lower among women receiving aspirin plus calcium than in the placebo group (52.2 vs 73.1%, respectively, P=0.112). The rate of fetal growth restriction was reduced by 80.8% in the supplemented group (25 vs 4.8% in the placebo vs supplemented groups, respectively; P=0.073). The rate of preterm birth was 33.3% in both groups. The combined supplementation of aspirin and calcium starting at 20-27 weeks of gestation produced a nonsignificant decrease in the incidence of superimposed preeclampsia and fetal growth restriction in hypertensive women with abnormal uterine artery Doppler.

  3. The Dahl salt-sensitive rat is a spontaneous model of superimposed preeclampsia.

    Science.gov (United States)

    Gillis, Ellen E; Williams, Jan M; Garrett, Michael R; Mooney, Jennifer N; Sasser, Jennifer M

    2015-07-01

    The mechanisms of the pathogenesis of preeclampsia, a leading cause of maternal morbidity and death worldwide, are poorly understood in part due to a lack of spontaneous animal models of the disease. We hypothesized that the Dahl salt-sensitive (S) rat, a genetic model of hypertension and kidney disease, is a spontaneous model of superimposed preeclampsia. The Dahl S was compared with the Sprague-Dawley (SD) rat, a strain with a well-characterized normal pregnancy, and the spontaneously hypertensive rat (SHR), a genetic model of hypertension that does not experience a preeclamptic phenotype despite preexisting hypertension. Mean arterial pressure (MAP, measured via telemetry) was elevated in the Dahl S and SHR before pregnancy, but hypertension was exacerbated during pregnancy only in Dahl S. In contrast, SD and SHR exhibited significant reductions in MAP consistent with normal pregnancy. Dahl S rats exhibited a severe increase in urinary protein excretion, glomerulomegaly, increased placental hypoxia, increased plasma soluble fms-like tyrosine kinase-1 (sFlt-1), and increased placental production of tumor necrosis factor-α (TNF-α). The Dahl S did not exhibit the expected decrease in uterine artery resistance during late pregnancy in contrast to the SD and SHR. Dahl S pups and litter sizes were smaller than in the SD. The Dahl S phenotype is consistent with many of the characteristics observed in human superimposed preeclampsia, and we propose that the Dahl S should be considered further as a spontaneous model to improve our understanding of the pathogenesis of superimposed preeclampsia and to identify and test new therapeutic targets for its treatment.

  4. Superimpose signal processing method for micro-scale thermal imaging of solar salts at high temperature

    Science.gov (United States)

    Morikawa, Junko; Zamengo, Massimiliano; Kato, Yukitaka

    2016-05-01

    The global interest in energy applications activates the advanced study about the molten salts in the usage of fluids in the power cycle, such as for transport and heat storage in solar power facilities. However, the basic properties of molten salts show a general scattering in characterization especially in thermal properties. It is suggested that new studies are required on the measurement of thermal properties of solar salts using recent technologies. In this study, micro-scale heat transfer and phase change in molten salts are presented using our originally developed device: the micro-bolometer Infrared focal plane arrays (IR FPA) measuring system is a portable type instrument, which is re-designed to measure the thermal phenomena in high temperature up to 700 °C or higher. The superimpose system is newly setup adjusted to the signal processing in high temperature to realize the quantitative thermal imaging, simultaneously. The portable type apparatus for a quantitative micro-scale thermography using a micro-bolometer has been proposed based on an achromatic lens design to capture a micro-scale image in the long-wave infrared, a video signal superimposing for the real time emissivity correction, and a pseudo acceleration of a timeframe. Combined with the superimpose technique, the micro-scale thermal imaging in high temperature is achieved and the molten flows of the solar salts, sodium nitrate, and potassium nitrate are successfully observed. The solar salt, the mixture of sodium nitrate and potassium nitrate, shows a different shape of exothermic heat front morphology in the lower phase transition (solidification) temperature than the nitrates on cooling. The proposed measuring technique will be utilized to accelerate the screening step to determine the phase diagram and the eutectics of the multiple mixtures of candidate molten salts, which may be used as heat transport medium from the concentrated solar power to a processing plant for thermal energy

  5. Pixelated speckle image holography carrier fringes for efficient superimposed light harvesting in organic solar cells

    Science.gov (United States)

    Zhou, Lei; Li, Yan-Qing; Chen, Jing-De; Ou, Qing-Dong; Tang, Jian-Xin; Zhou, Yun; Lin, Yi; Wei, Huai-Xin

    2017-06-01

    An inverted organic solar cell (OSC) device structure by incorporating pixelated speckle image holography carrier fringes (SIHFs) for efficient superimposed light harvesting is demonstrated. The proposed SIHF based OSCs yield an 18.2% increase in power conversion efficiency (PCE) compared to that of the flat control devices. Moreover, compared to the common two-dimensional (2D) periodic grating patterned OSCs, SIHF based devices achieve 7.8% higher short-circuit current (JSC) and 10.0% higher PCE. This observable improvement in PCE of SIHF based OSCs is mainly ascribed to the geometric effect due to the unique chaotic carrier fringes of SIHFs.

  6. Freezing, accelerating and slowing directed currents in real time with superimposed driven lattices

    CERN Document Server

    Mukhopadhyay, Aritra K; Wulf, Thomas; Schmelcher, Peter

    2016-01-01

    We provide a generic scheme offering real time control of directed particle transport in superimposed driven lattices. This scheme allows to accelerate, slow and freeze the transport on demand, by switching one of the lattices subsequently on and off. The underlying physical mechanism hinges on a systematic opening and closing of channels between transporting and non-transporting phase space structures upon switching, and exploits cantori structures which generate memory effects in the population of these structures. Our results should allow for real time control of cold thermal atomic ensembles in optical lattices, but might also be useful as a design principle for targeted delivery of molecules or colloids in optical devices.

  7. Buckling patterns of gold thin films on silicon substrates: Formation of superimposed blisters

    Science.gov (United States)

    Colin, J.; Coupeau, C.; Durinck, J.; Grilhé, J.

    2009-06-01

    Buckling phenomena leading to the formation of superimposed blisters have been experimentally observed with the help of a confocal interferometric microscope onto the surface of gold thin films deposited on silicon substrates. Assuming that residual folding effects resulting from plastic deformation mechanisms take place in the film during its morphological evolution, different probable scenarios for the formation of the observed buckling patterns are elaborated in the framework of the Föppl-von Karman's theory of thin plates. Multi-step buckling with growing interface delamination is considered for the first scenario while a single or multi-step buckling at a given delamination width is assumed for the other ones.

  8. [Relationship between jaws and the masseter muscle by superimposing MR images on the cephalogram].

    Science.gov (United States)

    Higashino, Ryoji

    2006-03-01

    The purpose of this study was to observe the morphological relationship between maxillofacial skeleton and masseter by superimposing the masseter image constructed by MR image scanning on the cephalogram. Sixteen subjects with different mandibular plane angle were examined in this study. Cephalogram and MR images of each subject were taken, and the images were input to a computer by using a digitizer. The areas of masseter were selected in each MR scan image which were projected to the mid-sagittal layer of the MR scan images. The synthesized image of cephalogram and masseter was obtained by completely superimposing sagittal images of the masseter with the mid-sagittal-plane MR image on the cephalogram. The inclination of masseter was determined by the center of gravity on the cross-section of masseter. These synthesized images of cephalogram and masseter showed various shapes of masseter according to different mandibular plane angle. The inclination of masseter had a close correlation with some skeletal parameters (mandibular plane angle, ANB, Y-axis, facial angle, saddle angle) of cephalometric analysis. The volume of the masseter also had a close correlation with skeletal parameters (mandibular plane angle, gonial angle, Y-axis). These results revealed that morphometric analysis using synthesized images of cephalogram and masseter is useful, and that the inclination and the volume of masseter may have an influence on the shape of the mandibular bone and its vertical and anteroposterior development.

  9. A System on a Programmable Chip Architecture for Data-Dependent Superimposed Training Channel Estimation

    Directory of Open Access Journals (Sweden)

    Fernando Martín del Campo

    2009-01-01

    with the information, a series of known symbols, whose analysis is used to define the parameters of the filters that remove the distortion of the data. Nevertheless, a part of the available bandwidth has to be destined to these symbols. Until now, no alternative solution has demonstrated to be fully satisfying for commercial use, but one technique that looks promising is superimposed training (ST. This work describes a hybrid software-hardware FPGA implementation of a recent algorithm that belongs to the ST family, known as Data-dependent Superimposed Training (DDST, which does not need extra bandwidth for its training sequences (TS as it adds them arithmetically to the data. DDST also adds a third sequence known as data-dependent sequence, that destroys the interference caused by the data over the TS. As DDST's computational burden is too high for the commercial processors used in mobile systems, a System on a Programmable Chip (SOPC approach is used in order to solve the problem.

  10. Simultaneously mapping and superimposing landmark configurations with parsimony as optimality criterion.

    Science.gov (United States)

    Catalano, S A; Goloboff, P A

    2012-05-01

    All methods proposed to date for mapping landmark configurations on a phylogenetic tree start from an alignment generated by methods that make no use of phylogenetic information, usually by superimposing all configurations against a consensus configuration. In order to properly interpret differences between landmark configurations along the tree as changes in shape, the metric chosen to define the ancestral assignments should also form the basis to superimpose the configurations. Thus, we present here a method that merges both steps, map and align, into a single procedure that (for the given tree) produces a multiple alignment and ancestral assignments such that the sum of the Euclidean distances between the corresponding landmarks along tree nodes is minimized. This approach is an extension of the method proposed by Catalano et al. (2010. Phylogenetic morphometrics (I): the use of landmark data in a phylogenetic framework. Cladistics. 26:539-549) for mapping landmark data with parsimony as optimality criterion. In the context of phylogenetics, this method allows maximizing the degree to which similarity in landmark positions can be accounted for by common ancestry. In the context of morphometrics, this approach guarantees (heuristics aside) that all the transformations inferred on the tree represent changes in shape. The performance of the method was evaluated on different data sets, indicating that the method produces marked improvements in tree score (up to 5% compared with generalized superimpositions, up to 11% compared with ordinary superimpositions). These empirical results stress the importance of incorporating the phylogenetic information into the alignment step.

  11. Bilateral rapidly destructive arthrosis of the hip joint resulting from subchondral fracture with superimposed secondary osteonecrosis

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Takuaki; Iwamoto, Yukihide [Kyushu University, Department of Orthopaedic Surgery, Fukuoka (Japan); Schneider, Robert [Hospital for Special Surgery, Department of Radiology, New York (United States); Bullough, Peter G. [Hospital for Special Surgery, Department of Laboratory Medicine, New York, NY (United States)

    2010-02-15

    A 57-year-old woman suffered rapid destruction of both hip joints over a 10 months period. At the first visit, her radiographs demonstrated slight joint space narrowing and acetabular cyst formation in both hips. Five months later, joint space narrowing had further progressed, and intra-articular injection of steroid was given in both hips. However, the hip pain gradually became worse. Five months later, both joint spaces had totally disappeared and both femoral heads had undergone massive collapse. At gross examination, both resected femoral heads showed extensive opaque yellow areas consistent with osteonecrosis. Microscopic examination of these areas revealed evidence of both extensive fracture and callus formation, as well as necrosis throughout, indicating that the osteonecrosis observed in this case was a secondary phenomenon superimposed on pre-existing osteoarthritis and subchondral fracture. There were many pseudogranulomatous lesions in the marrow space and necrotic area, where tiny fragments of bone and articular cartilage, surrounded by histiocytes and giant cells, were embedded, such as are typically seen in rapidly destructive arthrosis. No radiologic or morphologic evidence of primary osteonecrosis was noted. This case indicates that at least some cases of rapidly destructive arthritis are the result of subchondral fracture with superimposed secondary osteonecrosis. (orig.)

  12. Superimposed XOR: Approaching Capacity Bounds of the Two-Way Relay Channels

    CERN Document Server

    Liu, Jianquan; Xu, Youyun; Wang, Xiaodong

    2010-01-01

    In two-way relay channels, bitwise XOR and symbol-level superposition coding are two popular network-coding based relaying schemes. However, neither of them can approach the capacity bound when the channels in the broadcast phase are asymmetric. In this paper, we present a new physical layer network coding (PLNC) scheme, called \\emph{superimposed XOR}. The new scheme advances the existing schemes by specifically taking into account the channel asymmetry as well as information asymmetry in the broadcast phase. We obtain its achievable rate regions over Gaussian channels when integrated with two known time control protocols in two-way relaying. We also demonstrate their average maximum sum-rates and service delay performances over fading channels. Numerical results show that the proposed superimposed XOR achieves a larger rate region than both XOR and superposition and performs much better over fading channels. We further deduce the boundary of its achievable rate region of the broadcast phase in an explicit an...

  13. Design of air-gapped magnetic-core inductors for superimposed direct and alternating currents

    Science.gov (United States)

    Ohri, A. K.; Wilson, T. G.; Owen, H. A., Jr.

    1976-01-01

    Using data on standard magnetic-material properties and standard core sizes for air-gap-type cores, an algorithm designed for a computer solution is developed which optimally determines the air-gap length and locates the quiescent point on the normal magnetization curve so as to yield an inductor design with the minimum number of turns for a given ac voltage and frequency and with a given dc bias current superimposed in the same winding. Magnetic-material data used in the design are the normal magnetization curve and a family of incremental permeability curves. A second procedure, which requires a simpler set of calculations, starts from an assigned quiescent point on the normal magnetization curve and first screens candidate core sizes for suitability, then determines the required turns and air-gap length.

  14. Superimposed folding and thrusting by two phases of mutually orthogonal or oblique shortening in analogue models

    Science.gov (United States)

    Deng, Hongling; Koyi, Hemin A.; Nilfouroushan, Faramarz

    2016-02-01

    Orogens may suffer more than one phase shortening resulting in superposition of structures of different generations. Superimposition of orthogonal or oblique shortening is studied using sandbox and centrifuge modelling. Results of sand models show that in orthogonal superimposition, the two resulting structural trends are approximately orthogonal to each other. In oblique superimposition, structures trend obliquely to each other in the relatively thin areas of the model (foreland), and mutually orthogonal in areas where the model is thickened during the first phase of shortening (i.e. the hinterland). Thrusts formed during the first shortening phase may be reactivated during the later shortening phase. Spacing of the later phase structures is not as wide as expected, considering they across the pre-existing thickened wedge. Superposition of structures results in formation of type 1 fold interference pattern. Bedding is curved outwards both in the dome and basin structures. Folded layers are dipping and plunging outwards in a dome, while they are dipping and plunging inwards in a basin. In the areas between two adjacent domes or basins (i.e. where an anticline is superimposed by a syncline or a syncline is superimposed by an anticline), bedding is curved inwards, and the anticlines plunge inwards and the synclines outwards. The latter feature could be helpful to determine the age relationship for type 2 fold interference pattern. In tectonic regions where multiple phases of shortening have occurred, the orogenic-scale dome-and-basin and arrowhead-shaped interference patterns are commonly formed, as in the models. However, in some areas, the fold interference pattern might be modified by a later phase of thrusting. Similar to models results, superimposition of two and/or even more deformation phases may not be recorded by structures all over the tectonic area.

  15. Knee joint neuromuscular activation performance during muscle damage and superimposed fatigue.

    Science.gov (United States)

    Minshull, Claire; Eston, Roger; Rees, David; Gleeson, Nigel

    2012-01-01

    This study examined the concurrent effects of exercise-induced muscle damage and superimposed acute fatigue on the neuromuscular activation performance of the knee flexors of nine males (age: 26.7 ± 6.1 years; height 1.81 ± 0.05 m; body mass 81.2 ± 11.7 kg [mean±s]). Measures were obtained during three experimental conditions: (i) 'fatigue-muscle damage', involving acute fatiguing exercise performed on each assessment occasion plus a single episode of eccentric exercise performed on the first occasion and after the fatigue trial; (ii) 'fatigue', involving the fatiguing exercise only; and (iii) 'control' consisting of no exercise. Assessments were performed prior to (pre) and at 1 h, 24 h, 48 h, 72 h, and 168 h relative to the muscle damaging eccentric exercise. Repeated-measures analyses of variance (ANOVAs) showed that muscle damage elicited reductions of up to 38%, 24% and 65% in volitional peak force, electromechanical delay and rate of force development compared to baseline and controls, respectively (F ([10, 80]) = 2.3 to 4.6; P exercise.

  16. A case of extra hepatic portal vein obstruction in pregnancy with superimposed pre-eclampsia

    Directory of Open Access Journals (Sweden)

    Bindu Nambisan

    2016-09-01

    Full Text Available Extra hepatic portal vein obstruction in pregnancy poses a clinical challenge by itself. We present here a case of a 19 year old primigravida with EHPVO who developed superimposed preeclampsia. She had a successful maternal and fetal outcome in a tertiary care centre owing to the team effort involving specialists from medical gastroenterology, nephrology, anesthesiology, and neonatology apart from senior obstetrician. EHPVO is an important cause of non-cirrhotic portal hypertension in third world countries. In pregnancy, the increased blood volume and cardiac output and mesenteric vasodilatation will increase portal flow and aggravate portal hypertension in these patients. The resultant hematemesis in such patients, can compromise the perinatal outcome. Endoscopic variceal ligation (EVL reduces the risk of variceal bleeding, and can improve the pregnancy outcome in these women. Thrombocytopenia due to splenomegaly is one of the major complications in these patients and has to be corrected before pregnancy. Platelet transfusion is required intrapartum if the count is less than 50,000/mm3 caesarean delivery is reserved only for obstetric indications. [Int J Reprod Contracept Obstet Gynecol 2016; 5(9.000: 3213-3215

  17. Configurable Transmitter and Systolic Channel Estimator Architectures for Data-Dependent Superimposed Training Communications Systems

    Directory of Open Access Journals (Sweden)

    E. Romero-Aguirre

    2012-01-01

    Full Text Available In this paper, a configurable superimposed training (ST/data-dependent ST (DDST transmitter and architecture based on array processors (APs for DDST channel estimation are presented. Both architectures, designed under full-hardware paradigm, were described using Verilog HDL, targeted in Xilinx Virtex-5 and they were compared with existent approaches. The synthesis results showed a FPGA slice consumption of 1% for the transmitter and 3% for the estimator with 160 and 115 MHz operating frequencies, respectively. The signal-to-quantization-noise ratio (SQNR performance of the transmitter is about 82 dB to support 4/16/64-QAM modulation. A Monte Carlo simulation demonstrates that the mean square error (MSE of the channel estimator implemented in hardware is practically the same as the one obtained with the floating-point golden model. The high performance and reduced hardware of the proposed architectures lead to the conclusion that the DDST concept can be applied in current communications standards.

  18. Superimposed Pristine Limestone Aquifers with Marked Hydrochemical Differences Exhibit Distinct Fungal Communities

    Science.gov (United States)

    Nawaz, Ali; Purahong, Witoon; Lehmann, Robert; Herrmann, Martina; Küsel, Kirsten; Totsche, Kai U.; Buscot, François; Wubet, Tesfaye

    2016-01-01

    Fungi are one important group of eukaryotic microorganisms in a diverse range of ecosystems, but their diversity in groundwater ecosystems is largely unknown. We used DNA-based pyro-tag sequencing of the fungal internal transcribed spacer (ITS) rDNA gene to investigate the presence and community structure of fungi at different sampling sites of two superimposed limestone aquifers ranging from 8.5 to 84 m depth in the newly established Hainich Critical Zone Exploratory (Hainich CZE). We detected a diversity of fungal OTUs in groundwater samples of all sampling sites. The relative percentage abundance of Basidiomycota was higher in the upper aquifer assemblage, whilst Ascomycota dominated the lower one. In parallel to differences in the hydrochemistry we found distinct fungal communities at all sampling sites. Classification into functional groups revealed an overwhelming majority of saprotrophs. Finding taxa common to all analyzed groundwater sites, point to a groundwater specific fungal microbiome. The presence of different functional groups and, in particular plant and cattle pathogens that are not typical of subsurface habitats, suggests links between the surface and subsurface biogeosphere due to rapid transportation across the fracture networks typical of karstic regions during recharge episodes. However, further studies including sampling series extended in both time and space are necessary to confirm this hypothesis. PMID:27242696

  19. Dunes morphologies and superimposed bedforms in a cellular automaton dune model

    Science.gov (United States)

    Zhang, D.; Narteau, C.; Rozier, O.; Claudin, P.

    2009-04-01

    We use a new 3D cellular automaton model for bedform dynamics in which individual physical processes such as erosion, deposition and transport are implemented by nearest neighbor interactions and a time-dependent stochastic process. Simultaneously, a lattice gas cellular automaton model is used to compute the flow and quantify the bed shear stress on the topography. Local erosion rates are taken proportional to the shear stress in such a way that there is a complete feedback mechanism between flow and bedform dynamics. In the numerical simulations of dune fields, we observe the formation and the evolution of barchan, transverse, longitudinal and star dunes. For all these types of dunes, we observe the emergence of superimposed bedforms when dunes are large enough. Then, we use the same model under different initial conditions, and we perform the linear stability analysis of a flat sand bed disturbed by a small sinusoidal perturbation. Comparing the most unstable wavelength in the model with the characteristic size of secondary bedforms in nature, we determine the length and time scales of our cellular automaton model. Thus, we establish a link between discrete and continuous approaches and open new perspectives for modeling and quantification of complex patterns in dune fields.

  20. Research on a Composite Power-Superimposed Ultrasonic Vibrator for Wire Drawing

    Directory of Open Access Journals (Sweden)

    Shen Liu

    2016-01-01

    Full Text Available Vibration power and amplitude are essential factors in ultrasonic drawing processes, especially for difficult-to-draw materials like titanium and its alloys. This paper presents a new composite power-superimposed ultrasonic vibrator for wire drawing which was driven by three separate ultrasonic transducers. The transducers were uniformly distributed around the circular cross section of the vibrator, with their axes along the radial direction and pointing to the center. The vibrator can concentrate the vibrational energy of multiple transducers and transform the radial vibration into a longitudinal vibrator because of the Poisson effect and therefore output larger vibration power and amplitude. In the paper, the four-terminal network method was used to establish the vibration equations of the vibrator. The FE model was established in ANSYS to investigate its characteristics under various excitation conditions. A prototype was manufactured and measurements were performed to verify the validation of FEA results. The results matched well with the theoretical results. It was found that the composite vibrator achieved an amplitude of about 40 μm when driven by square wave signals with 120° in phase difference, which implies a potential way of applying ultrasonic vibration to the processing of difficult-to-draw materials.

  1. Optimal Superimposed Training Sequences for Channel Estimation in MIMO-OFDM Systems

    Directory of Open Access Journals (Sweden)

    Ratnam V. Raja Kumar

    2010-01-01

    Full Text Available In this work an iterative time domain Least Squares (LS based channel estimation method using superimposed training (ST for a Multiple Input Multiple Output Orthogonal Frequency Division Multiplexing (MIMO-OFDM system over time varying frequency selective fading channels is proposed. The performance of the channel estimator is analyzed in terms of the Mean Square Estimation Error (MSEE and its impact on the uncoded Bit Error Rate (BER of the MIMO-OFDM system is studied. A new selection criterion for the training sequences that jointly optimizes the MSEE and the BER of the OFDM system is proposed. Chirp based sequences are proposed and shown to satisfy the same. These are compared with the other sequences proposed in the literature and are found to yield a superior performance. The sequences, one for each transmitting antenna, offers fairness through providing equal interference in all the data carriers unlike earlier proposals. The effectiveness of the mathematical analysis presented is demonstrated through a comparison with the simulation studies. Experimental studies are carried out to study and validate the improved performance of the proposed scheme. The scheme is applied to the IEEE 802.16e OFDM standard and a case is made with the required design of the sequence.

  2. Comparison of different undulator schemes with superimposed alternating gradients for the VUV-FEL at the TESLA Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Pflueger, J.; Nikitina, Y.M. [DESY/HASYLAB, Hamburg (Germany)

    1995-12-31

    For the VUV-FEL at the TESLA Test Facility an undulator with a total length of 30 m is needed. In this study three different approaches to realize an undulator with a sinusoidal plus a superimposed quadrupolar field were studied with the 3D code MAFIA.

  3. Poly-phase salt tectonics and hydrocarbon accumulation in Tarim superimposed basin, northwest China

    Institute of Scientific and Technical Information of China (English)

    TANG Liangjie; JIN Zhijun; JlA Chengzao; PI Xuejun; CHEN Suping

    2004-01-01

    The purpose of this paper is to discuss the poly-phase salt tectonics and its relation to the hydrocarbon accumulation of the Tarim superimposed basin. Several salt sequences are developed in the Tarim basin, they are: (1) the Mid-Early Cambrian salt sequence, mainly distributed in the west part of the north Tarim uplift and Keping uplift; (2) the Early Carboniferous salt sequence, mainly distributed in the south slope of the north Tarim uplift; (3) the Paleogene salt sequence, mainly distributed in the mid-west part of the Kuqa foreland fold belt and north Tarim uplift; and (4) the Miocene salt sequence, mainly distributed in the east part of the Kuqa foreland fold belt. The salt sequences deposited in the tectonically calm scenario, while the salt layers deformed during the period of intense tectonism. Although the salt sequences are characteristic of plastic flow, the differences of salt deformation styles exist in the different salt sequences because of the different deformation mechanism. It is attractive that the distribution of the large oil-gas fields or pools has a bearing upon the salt sequences and salt structures, such as the Tahe oilfield related to the Lower Carboniferous salt sequence and laterally facies changed mudstone, the Kela No.2 gas field to the Paleogene salt structures, and the Dina gas field to the Miocene salt structures. It is indicated that the large-scale hydrocarbon accumulation is controlled by the poly-phase salt sequences and structures. The deep analysis of the poly-phase salt tectonics is helpful to understanding the characteristics of the structural deformation and oil-gas accumulation of the Tarim basin.

  4. [Tubeless superimposed high frequency jet ventilation in high grade laryngeal stenoses].

    Science.gov (United States)

    Aloy, A; Kimla, T; Schragl, E; Donner, A; Grasl, M

    1994-08-01

    Massive stenosis of the larynx may present a potentially life-threatening situation for the patient, requiring immediate measures to ensure a patient's airway. The aim of this prospective study was to evaluate potential benefits of Superimposed High Frequency Jet Ventilation (SHFJV) in patients requiring microlaryngeal surgery due to massive stenosis of the larynx. 23 patients (age range 1.5 to 90 years) with laryngeal stenosis grade 2 and 3 according to the Cotton scale were ventilated using SHFJV. The duration of the SHFJV was 12 to 116 minutes. SHFJV was performed using a Bronchotron Respirator via a jet-laryngoscope. Arterial blood gases demonstrated paO2 between 71 and 295 mmHg and paCO2 of 28 to 81 mmHg. The mean FiO2 applied was 61.75 +/- 19.26. The airway pressure was measured at the tip of the jet-laryngoscope and was between 6 and 15 mmHg, and PEEP was 1 to 5 mmHg. In 13 patients a CO2 laser was utilised during surgery. In all patients SHFJV was performed without problems. Since the ventilation is delivered above any possible stenosis the danger of barotrauma is minimised. The surgeon obtains optimal visibility of the larynx and is not obstructed in the surgical procedure. SHFJV enables both the surgeon and the anesthetist to perform their respective duties and therefore increases the safety of the patient in the management of such a difficult problem as massive stenosis of the larynx.

  5. Incidence and pregnancy outcomes of superimposed preeclampsia with or without proteinuria among women with chronic hypertension.

    Science.gov (United States)

    Nakanishi, Sayuri; Aoki, Shigeru; Nagashima, Ami; Seki, Kazuo

    2017-01-01

    To investigate the incidence and pregnancy outcomes of superimposed preeclampsia (PE) with or without proteinuria among women with chronic hypertension. This retrospective study included 142 women with essential hypertension diagnosed at ⩽20weeks of gestation, managed at a tertiary center. They were divided into three groups (non-PE, PE with proteinuria, and PE without proteinuria) to compare pregnancy outcomes. The non-PE group was further divided into two subgroups (controlled and uncontrolled hypertension). There were 87 women in the non-PE group, 47 in the PE with proteinuria group, and 8 in the PE without proteinuria group. Median gestational age at delivery was 38.7weeks in the non-PE group, 30.4 in the PE with proteinuria group, and 28.4 in the PE without proteinuria group. In three of the women in the PE without proteinuria group, the diagnostic criteria were fulfilled by liver involvement (complicated by thrombocytopenia in one woman). The remaining five women had uteroplacental dysfunction. The 87 women in the non-PE group were divided into a controlled hypertension subgroup of 75 women and uncontrolled hypertension subgroup of 12. The median gestational age at delivery was 39.1weeks in the controlled HT subgroup and 34.1weeks in the uncontrolled hypertension subgroup. The pregnancy outcomes were significantly poorer in the latter group. Pregnancy outcomes were unfavorable in both the PE without proteinuria and PE with proteinuria groups. Women with non-PE uncontrolled hypertension also had poor pregnancy outcomes, although their outcomes were better than those of women with PE. Copyright © 2017 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.

  6. Alteration and Reformation of Hydrocarbon Reservoirs and Prediction of Remaining Potential Resources in Superimposed Basins

    Institute of Scientific and Technical Information of China (English)

    PANG Hong; PANG Xiongqi; YANG Haijun; LIN Changsong; MENG Qingyang; WANG Huaijie

    2010-01-01

    Complex hydrocarbon reservoirs developed widely in the superimposed basins of China formed from multiple structural alterations,reformation and destruction of hydrocarbon reservoirs formed at early stages.They are characterized currently by trap adjustment,component variation,phase conversion,and scale reformation.This is significant for guiding current hydrocarbon exploration by revealing evolution mechanisms after hydrocarbon reservoir formation and for predicting remaining potential resources.Based on the analysis of a number of complex hydrocarbon reservoirs,there are four geologic features controlling the degree of destruction of hydrocarbon reservoirs formed at early stages:tectonic event intensity,frequency,time and caprock sealing for oil and gas during tectonic evolution.Research shows that the larger the tectonic event intensity,the more frequent the tectonic event,the later the last tectonic event,the weaker the caprock sealing for oil and gas,and the greater the volume of destroyed hydrocarbons in the early stages.Based on research on the main controlling factors of hydrocarbon reservoir destruction mechanisms,a geological model of tectonic superimposition and a mathematical model evaluating potential remaining complex hydrocarbon reservoirs have been established.The predication method and technical procedures were applied in the Tazhong area of Tarim Basin,where four stages of hydrocarbon accumulation and three stages of hydrocarbon alteration occurred.Geohistorical hydrocarbon accumulation reached 3.184billion tons,of which 1.271 billion tons were destroyed.The total volume of remaining resources available for exploration is~1.9 billion tons.

  7. A New Catalogue of Fine Structures Superimposed on Solar Microwave Bursts

    Institute of Scientific and Technical Information of China (English)

    Qi-Jun Fu; Yi-Hua Yan; Yu-Ying Liu; Min Wang; Shu-Juan Wang

    2004-01-01

    The 2.6-3.8 GHz, 4.5-7.5 GHz, 5.2-7.6 GHz and 0.7-1.5 GHz component spectrometers of Solar Broadband Radio Spectrometer (SBRS) started routine observations, respectively, in late August 1996, August 1999, August 1999, and June 2000. They just managed to catch the coming 23rd solar active maximum. Consequently, a large amount of microwave burst data with high temporal and high spectral resolution and high sensitivity were obtained. A variety of fine structures (FS)superimposed on microwave bursts have been found. Some of them are known, such as microwave type Ⅲ bursts, microwave spike emission, but these were observed with more detail; some are new. Reported for the first time here are microwave type U bursts with similar spectral morphology to those in decimetric and metric wavelengths, and with outstanding characteristics such as very short durations(tens to hundreds ms), narrow bandwidths, higher frequency drift rates and higher degrees of polarization. Type N and type M bursts were also observed. Detailed zebra pattern and fiber bursts at the high frequency were found. Drifting pulsation structure (DPS) phenomena closely associated with CME are considered to manifest the initial phase of the CME, and quasi-periodic pulsation with periods of tens ms have been recorded. Microwave "patches", unlike those reported previously, were observed with very short durations (about 300 ms), very high flux densities (up to 1000 sfu), very high polarization (about 100% RCP), extremely narrow bandwidths(about 5%), and very high spectral indexes. These cannot be interpreted with the gyrosynchrotron process. A superfine structure in the form of microwave FS (ZPS,type U), consisting of microwave millisecond spike emission (MMS), was also found.

  8. Augmented vascular smooth muscle cell stiffness and adhesion when hypertension is superimposed on aging.

    Science.gov (United States)

    Sehgel, Nancy L; Sun, Zhe; Hong, Zhongkui; Hunter, William C; Hill, Michael A; Vatner, Dorothy E; Vatner, Stephen F; Meininger, Gerald A

    2015-02-01

    Hypertension and aging are both recognized to increase aortic stiffness, but their interactions are not completely understood. Most previous studies have attributed increased aortic stiffness to changes in extracellular matrix proteins that alter the mechanical properties of the vascular wall. Alternatively, we hypothesized that a significant component of increased vascular stiffness in hypertension is due to changes in the mechanical and adhesive properties of vascular smooth muscle cells, and that aging would augment the contribution from vascular smooth muscle cells when compared with the extracellular matrix. Accordingly, we studied aortic stiffness in young (16-week-old) and old (64-week-old) spontaneously hypertensive rats and Wistar-Kyoto wild-type controls. Systolic and pulse pressures were significantly increased in young spontaneously hypertensive rats when compared with young Wistar-Kyoto rats, and these continued to rise in old spontaneously hypertensive rats when compared with age-matched controls. Excised aortic ring segments exhibited significantly greater elastic moduli in both young and old spontaneously hypertensive rats versus Wistar-Kyoto rats. were isolated from the thoracic aorta, and stiffness and adhesion to fibronectin were measured by atomic force microscopy. Hypertension increased both vascular smooth muscle cell stiffness and vascular smooth muscle cell adhesion, and these increases were both augmented with aging. By contrast, hypertension did not affect histological measures of aortic collagen and elastin, which were predominantly changed by aging. These findings support the concept that stiffness and adhesive properties of vascular smooth muscle cells are novel mechanisms contributing to the increased aortic stiffness occurring with hypertension superimposed on aging.

  9. Delirium Superimposed on Dementia Strongly Predicts Worse Outcomes in Older Rehabilitation Inpatients

    Science.gov (United States)

    Morandi, Alessandro; Davis, Daniel; Fick, Donna M.; Turco, Renato; Boustani, Malaz; Lucchi, Elena; Guerini, Fabio; Morghen, Sara; Torpilliesi, Tiziana; Gentile, Simona; MacLullich, Alasdair M.; Trabucchi, Marco; Bellelli, Giuseppe

    2014-01-01

    Objective Delirium superimposed on dementia (DSD) is common in many settings. Nonetheless, little is known about the association between DSD and clinical outcomes. The study aim was to evaluate the association between DSD and related adverse outcomes at discharge from rehabilitation and at 1-year follow-up in older inpatients undergoing rehabilitation. Design Prospective cohort study. Setting Hospital rehabilitation unit. Participants A total of 2642 patients aged 65 years or older admitted between January 2002 and December 2006. Measurements Dementia predating rehabilitation admission was detected by DSM-III-R criteria. Delirium was diagnosed with the DSM-IV-TR. The primary outcome was that of walking dependence (Barthel Index mobility subitem score of <15) captured as a trajectory from discharge to 1-year follow-up. A mixed-effects multivariate logistic regression model was used to analyze the association between DSD and outcome, after adjusting for relevant covariates. Secondary outcomes were institutionalization and mortality at 1-year follow-up, and logistic regression models were used to analyze these associations. Results The median age was 77 years (interquartile range: 71–83). The prevalence of DSD was 8%, and the prevalence of delirium and dementia alone were 4% and 22%, respectively. DSD at admission was found to be significantly associated with almost a 15-fold increase in the odds of walking dependence (odds ratio [OR] 15.5; 95% Confidence Interval [CI] 5.6–42.7; P < .01). DSD was also significantly associated with a fivefold increase in the risk of institutionalization (OR 5.0; 95% CI 2.8–8.9; P < .01) and an almost twofold increase in the risk of mortality (OR 1.8; 95% CI 1.1–2.8; P = .01). Conclusions DSD is a strong predictor of functional dependence, institutionalization, and mortality in older patients admitted to a rehabilitation setting, suggesting that strategies to detect DSD routinely in practice should be developed and DSD should

  10. Superimposed epitopes restricted by the same HLA molecule drive distinct HIV-specific CD8+ T cell repertoires.

    Science.gov (United States)

    Sun, Xiaoming; Fujiwara, Mamoru; Shi, Yi; Kuse, Nozomi; Gatanaga, Hiroyuki; Appay, Victor; Gao, George F; Oka, Shinichi; Takiguchi, Masafumi

    2014-07-01

    Superimposed epitopes, in which a shorter epitope is embedded within a longer one, can be presented by the same HLA class I molecule. CD8(+) CTL responses against such epitopes and the contribution of this phenomenon to immune control are poorly characterized. In this study, we examined HLA-A*24:02-restricted CTLs specific for the superimposed HIV Nef epitopes RYPLTFGWCF (RF10) and RYPLTFGW (RW8). Unexpectedly, RF10-specific and RW8-specific CTLs from HIV-1-infected HLA-A*24:02+ individuals had no overlapping Ag reactivity or clonotypic compositions. Single-cell TCR sequence analyses demonstrated that RF10-specific T cells had a more diverse TCR repertoire than did RW8-specific T cells. Furthermore, RF10-specific CTLs presented a higher Ag sensitivity and HIV suppressive capacity compared with RW8-specific CTLs. Crystallographic analyses revealed important structural differences between RF10- and RW8-HLA-A*24:02 complexes as well, with featured and featureless conformations, respectively, providing an explanation for the induction of distinct T cell responses against these epitopes. The present study shows that a single viral sequence containing superimposed epitopes restricted by the same HLA molecule could elicit distinct CD8+ T cell responses, therefore enhancing the control of HIV replication. This study also showed that a featured epitope (e.g., RF10) could drive the induction of T cells with high TCR diversity and affinity. Copyright © 2014 by The American Association of Immunologists, Inc.

  11. Association between delirium superimposed on dementia and mortality in hospitalized older adults: A prospective cohort study

    Science.gov (United States)

    Curiati, Jose A. E.; Jacob-Filho, Wilson

    2017-01-01

    Background Hospitalized older adults with preexisting dementia have increased risk of having delirium, but little is known regarding the effect of delirium superimposed on dementia (DSD) on the outcomes of these patients. Our aim was to investigate the association between DSD and hospital mortality and 12-mo mortality in hospitalized older adults. Methods and findings This was a prospective cohort study completed in the geriatric ward of a university hospital in São Paulo, Brazil. We included 1,409 hospitalizations of acutely ill patients aged 60 y and over from January 2009 to June 2015. Main variables and measures included dementia and dementia severity (Informant Questionnaire on Cognitive Decline in the Elderly, Clinical Dementia Rating) and delirium (Confusion Assessment Method). Primary outcomes were time to death in the hospital and time to death in 12 mo (for the discharged sample). Comprehensive geriatric assessment was performed at admission, and additional clinical data were documented upon death or discharge. Cases were categorized into four groups (no delirium or dementia, dementia alone, delirium alone, and DSD). The no delirium/dementia group was defined as the referent category for comparisons, and multivariate analyses were performed using Cox proportional hazards models adjusted for possible confounders (sociodemographic information, medical history and physical examination data, functional and nutritional status, polypharmacy, and laboratory covariates). Overall, 61% were women and 39% had dementia, with a mean age of 80 y. Dementia alone was observed in 13% of the cases, with delirium alone in 21% and DSD in 26% of the cases. In-hospital mortality was 8% for patients without delirium or dementia, 12% for patients with dementia alone, 29% for patients with delirium alone, and 32% for DSD patients (Pearson Chi-square = 112, p < 0.001). DSD and delirium alone were independently associated with in-hospital mortality, with respective hazard ratios

  12. Simultaneous ultrafast optical pulse train bursts generation and shaping based on Fourier series developments using superimposed fiber Bragg gratings.

    Science.gov (United States)

    García-Muñoz, Víctor; Preciado, Miguel A; Muriel, Miguel A

    2007-08-20

    We propose an all-fiber method for the generation of ultrafast shaped pulse train bursts from a single pulse based on Fourier Series Developments (FDSs). The implementation of the FSD based filter only requires the use of a very simple non apodized Superimposed Fiber Bragg Grating (S-FBG) for the generation of the Shaped Output Pulse Train Burst (SOPTB). In this approach, the shape, the period and the temporal length of the generated SOPTB have no dependency on the input pulse rate.

  13. Recent developments in study of the typical superimposed basins and petroleum accumulation in China:Exemplified by the Tarim Basin

    Institute of Scientific and Technical Information of China (English)

    JIN Zhijun; WANG Qingchen

    2004-01-01

    Most of petroliferous sedimentary basins in China have experienced multiple phases of tectonic evolution and deposition, and are characterized by tectonic and depositional superimposition. The term "superimposed basin" is suggested to describe those basins which consist of two or more simple prototype basins superimposing vertically and/or coalescing laterally. The characteristics of petroliferous superimposed basins are "multiple stages of basin forming and reworking, multiple layers of source rocks, multiple periods of hydrocarbon generation and expulsion, multiple periods of petroleum migration-accumulation-escape". Therefore,applying the wave process analysis method to studying the process of basin formation, hydrocarbon generation, and reservoir formation, and then establishing theory of "petroleum accumulation system" is helpful to enhancing petroleum exploration efficiency in superimposed basins.This paper will, based on case study in the Tarim basin, report the major developments in studying basin formation, hydrocarbon generation and petroleum accumulation. In study of basin formation, (1) geophysical comprehensive profiles reveal that the Tarim plate has been subducted beneath the Tianshan orogenic belt with an interfinger structure and that the deep structure in the eastern section of the Tianshan orogenic belt is different from that in the western section. (2) The vertical variation in debris and geochemical composition reveals the nature and Mesozoic-Cenozoic evolution history of the Kuqa Depression. (3) Field investigation and paleostress reconstruction show that the Kuqa Depression has undergone gravity-driven extension in sedimentary cover when the Tianshan uplifted vertically. In hydrocarbon generation study, new developments include (1) setting environmental index to judge high grade source rocks in marine carbonates, and (2) establishing the lower limit of the organic carbon content for effective carbonate source rocks. In petroleum accumulation

  14. Recent developments in study of the typical superimposed basins and petroleum accumulation in China: Exemplified by the Tarim Basin

    Institute of Scientific and Technical Information of China (English)

    JIN; Zhijun; WANG; Qingchen

    2004-01-01

    Most of petroliferous sedimentary basins in China have experienced multiple phases of tectonic evolution and deposition, and are characterized by tectonic and depositional superimposition. The term "superimposed basin" is suggested to describe those basins which consist of two or more simple prototype basins superimposing vertically and/or coalescing laterally. The characteristics of petroliferous superimposed basins are "multiple stages of basin forming and reworking, multiple layers of source rocks, multiple periods of hydrocarbon generation and expulsion, multiple periods of petroleum migration-accumulation-escape". Therefore,applying the wave process analysis method to studying the process of basin formation, hydrocarbon generation, and reservoir formation, and then establishing theory of "petroleum accumulation system" is helpful to enhancing petroleum exploration efficiency in superimposed basins.This paper will, based on case study in the Tarim basin, report the major developments in studying basin formation, hydrocarbon generation and petroleum accumulation. In study of basin formation, (1) geophysical comprehensive profiles reveal that the Tarim plate has been subducted beneath the Tianshan orogenic belt with an interfinger structure and that the deep structure in the eastern section of the Tianshan orogenic belt is different from that in the western section. (2) The vertical variation in debris and geochemical composition reveals the nature and Mesozoic-Cenozoic evolution history of the Kuqa Depression. (3) Field investigation and paleostress reconstruction show that the Kuqa Depression has undergone gravity-driven extension in sedimentary cover when the Tianshan uplifted vertically. In hydrocarbon generation study, new developments include (1) setting environmental index to judge high grade source rocks in marine carbonates, and (2) establishing the lower limit of the organic carbon content for effective carbonate source rocks. In petroleum accumulation

  15. Vulvar and Perianal Condyloma Superimposed Inflammatory Linear Verrucous Epidermal Nevus: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Sümeyra Nergız Avcioğlu

    2013-01-01

    Full Text Available Inflammatory linear verrucous epidermal nevus (ILVEN is a benign cutaneous hamartoma characterized by intensely erythematous, pruritic, and inflammatory papules that occur as linear bands along the lines of Blaschko. There is a considerable clinical and histological resemblance between ILVEN and linear psoriasis, lichen striatus, linear lichen planus, and invasion of epidermal nevus by psoriasis. The pathogenesis of ILVEN is unknown. It is regarded as a genetic dyskeratotic disease reflecting genetic mosaicism. Here, a case of vulvar and perianal condyloma superimposed ILVEN is presented.

  16. Using Standardized Case Vignettes to Evaluate Nursing Home Staff Recognition of Delirium and Delirium Superimposed on Dementia

    Science.gov (United States)

    Fick, Donna M.; Kolanowski, Ann M.; Hill, Nikki L.; Yevchak, Andrea; DiMeglio, Brittney; Mulhall, Paula M.

    2014-01-01

    The purpose of this study is to describe nursing home staff knowledge regarding delirium detection and the most common causes of delirium. Specific aims that guided this study include identifying the rate of nurse recognition of delirium and delirium superimposed on dementia (DSD), including different motoric subtypes of delirium, using standardized case vignettes, and exploring what nursing home staff describe as the potential causes of delirium. The study showed overall poor recognition of delirium and DSD, which did not improve over time. Interventions have the potential to increase the early detection of delirium and DSD by the staff and warrant development. PMID:25400513

  17. Experimental investigation of SDBD plasma actuator driven by AC high voltage with a superimposed positive pulse bias voltage

    Science.gov (United States)

    Qi, Xiao-Hua; Yan, Hui-Jie; Yang, Liang; Hua, Yue; Ren, Chun-Sheng

    2017-08-01

    In this work, a driven voltage consisting of AC high voltage with a superimposed positive pulse bias voltage ("AC+ Positive pulse bias" voltage) is adopted to study the performance of a surface dielectric barrier discharge plasma actuator under atmospheric conditions. To compare the performance of the actuator driven by single-AC voltage and "AC+ Positive pulse bias" voltage, the actuator-induced thrust force and power consumption are measured as a function of the applied AC voltage, and the measured results indicate that the thrust force can be promoted significantly after superimposing the positive pulse bias voltage. The physical mechanism behind the thrust force changes is analyzed by measuring the optical properties, electrical characteristics, and surface potential distribution. Experimental results indicate that the glow-like discharge in the AC voltage half-cycle, next to the cycle where a bias voltage pulse has been applied, is enhanced after applying the positive pulse bias voltage, and this perhaps is the main reason for the thrust force increase. Moreover, surface potential measurement results reveal that the spatial electric field formed by the surface charge accumulation after positive pulse discharge can significantly affect the applied external electric field, and this perhaps can be responsible for the experimental phenomenon that the decrease of thrust force is delayed by pulse bias voltage action after the filament discharge occurs in the glow-like discharge region. The schlieren images further verify that the actuator-induced airflow velocity increases with the positive pulse voltage.

  18. Combined multi-nozzle deposition and freeze casting process to superimpose two porous networks for hierarchical three-dimensional microenvironment.

    Science.gov (United States)

    Snyder, Jessica E; Hunger, Philipp M; Wang, Chengyang; Hamid, Qudus; Wegst, Ulrike G K; Sun, Wei

    2014-03-01

    An engineered three-dimensional scaffold with hierarchical porosity and multiple niche microenvironments is produced using a combined multi-nozzle deposition-freeze casting technique. In this paper we present a process to fabricate a scaffold with improved interconnectivity and hierarchical porosity. The scaffold is produced using a two-stage manufacturing process which superimposes a printed porous alginate (Alg) network and a directionally frozen ceramic-polymer matrix. The combination of two processes, multi-nozzle deposition and freeze casting, provides engineering control of the microenvironment of the scaffolds over several length scales; including the addition of lateral porosity and the ratio of polymer to ceramic microstructures. The printed polymer scaffold is submerged in a ceramic-polymer slurry and subsequently, both structures are directionally frozen (freeze cast), superimposing and patterning both microenvironments into a single hierarchical architecture. An optional additional sintering step removes the organic material and densifies the ceramic phase to produce a well-defined network of open pores and a homogenous cell wall material composition. The techniques presented in this contribution address processing challenges, such as structure definition, reproducibility and fine adjustments of unique length scales, which one typically encounters when fabricating topological channels between longitudinal and transverse porous networks.

  19. The algorithm of decomposing superimposed 2-D Poisson processes and its application to the extracting earthquake clustering pattern

    Institute of Scientific and Technical Information of China (English)

    裴韬; 周成虎; 杨明; 骆剑承; 李全林

    2004-01-01

    Aiming at the complexity of seismic gestation mechanism and spatial distribution, we hypothesize that the seismic data are composed of background earthquakes and anomaly earthquakes in a certain temporal-spatial scope. Also the background earthquakes and anomaly earthquakes both satisfy the 2-D Poisson process of different parameters respectively. In the paper, the concept of N-th order distance is introduced in order to transform 2-D superimposed Poisson process into 1-D mixture density function. On the basis of choosing the distance, mixture density function is decomposed to recognize the anomaly earthquakes through genetic algorithm. Combined with the temporal scanning of C value, the algorithm is applied to the recognition on spatial pattern of foreshock anomalies by examples of Songpan and Longling sequences in the southwest of China.

  20. Black-spot poison ivy dermatitis. An acute irritant contact dermatitis superimposed upon an allergic contact dermatitis.

    Science.gov (United States)

    Hurwitz, R M; Rivera, H P; Guin, J D

    1984-08-01

    A black spot in the epidermis over a blister of poison ivy dermatitis is an uncommon finding. Four patients with the phenomenon are described. Histologic and histochemical studies were made on biopsy material and the blackish deposit on the skin surface was compared with black deposits in and on leaves of the species of poison ivy. This examination revealed a yellow, amorphous substance on the stratum corneum of the lesions and a similar substance in and on leaves of the poison ivy plant, Toxicodendron radicans ssp. negundo. Associated with the pigmentary deposits there were distinct changes of acute irritant contact dermatitis superimposed upon allergic contact dermatitis. Our findings support the view that the black material is the oleoresin of the plant, and that this substance behaves both as an irritant and an allergen.

  1. Metallogenetic Mechanism and Timing of Late Superimposing Fluid Mineralization in the Dongguashan Diplogenetic Stratified Copper Deposit, Anhui Province

    Institute of Scientific and Technical Information of China (English)

    XU Zhaowen; LU Xiancai; LING Hongfei; LU Jianjun; JIANG Shoyong; NIE Guiping; HUANG Shunsheng; HUA Ming

    2005-01-01

    An important diplogenetic mineralization event superimposed on pre-existing exhalation sediments in the Tongling area, Anhui province, was triggered by widespread granitic magmatism along the northeastern margin of the Yangtze Block during 140-135 Ma under extensional tectonic circumstances following the collision between the North China and Yangtze blocks. The main orebodies of the Dongguashan copper deposit, a typical diplogenetic stratified deposit among many polymetallic ore deposits in China, are hosted by strata between Upper Devonian sandstone and Carboniferous limestone, and its mineralization was genetically related to the Qingshanjiao intrusive. The Rb-Sr isotopic isochron of the Qingshanjiao intrusive yields an age of about 136.5±1.4 Ma. The ore-forming fluid reflected by the inclusion fluid in quartz veins is characterized by high temperature and high salinity, and its age was also determined by Rb-Sr isotope dating as 134±11 Ma. Oxygen and hydrogen isotope composition data suggest that the ore-forming fluid was derived mainly from magmatism. By integrating these isotopic dating data, characteristics of fluid inclusions and the geology of the deposit, the mineralization of the Dongguashan copper deposit is divided into two stages. First, a stratiform sedimentary deposit or protore layer formed in the Late Devonian to the Early Carboniferous, while in the second stage the pre-existing protore was superimposed by hydrothermal fluid that was derived from the Yanshanian magmatic activities occurring around 135 Ma ago. This two-stage mineralization formed the Dongguashan statiform copper deposit.Associated "porphyry" mineralization found in the bottom of and in surrounding intrusive rocks of the orebodies might have occurred in the same period as a second-stage mineralization of this deposit.

  2. Numerical Investigations on the Influence of Superimposed Double-Sided Pressure on the Formability of Biaxially Stretched AA6111-T4 Sheet Metal

    Science.gov (United States)

    Liu, Jianguang; Wang, Zhongjin; Meng, Qingyuan

    2012-04-01

    Lightweight materials have been widely used in aerospace, automobile industries to meet the requirement of structural weight reduction. Due to their limited plasticity at room temperature, however, lightweight materials always exhibit distinctly poor forming capability in comparison with conventional deep drawing steels. Based on the phenomenon that the superimposed hydrostatic pressure can improve the plasticity of metal, many kinds of double-sided pressure forming processes have been proposed. In the present study, the Gurson-Tvergaard-Needleman (GTN) damage model combined with finite element method is used to investigate the influence of double-sided pressure on the deformation behavior of biaxially stretched AA6111-T4 sheet metal, including nucleation and growth of microvoids, evaluation of stress triaxiality, and so forth. The Marciniak-Kuczynski (M-K) localized necking model is used to predict the right-hand side of the forming limit diagram (FLD) of sheet metal under superimposed double-sided pressure. It is found that the superimposed double-sided pressure has no obvious effect on the nucleation of microvoids. However, the superimposed double-sided pressure can suppress the growth and coalescence of microvoids. The forming limit curve (FLC) of the biaxially stretched AA6111-T4 sheet metal under the superimposed double-sided pressure is improved and the fracture locus shifts to the left. Furthermore, the formability increase value is sensitive to the strain path.

  3. Resolution of superimposed pre-eclampsia, and improvement in umbilical artery flow in a surviving twin after intrauterine demise of its co-twin.

    Science.gov (United States)

    Narasimhulu, Deepa M; Karakash, Scarlett; Rankin, Linda; Minkoff, Howard

    2015-09-01

    Pre-eclampsia has a progressive clinical course, and is only cured by delivery of the placenta. We report a 30-year-old G1P0 with dichorionic twins, discordant growth and chronic hypertension who developed superimposed pre-eclampsia in her 21st week of gestation. After intrauterine demise of the severely growth-restricted twin, the superimposed pre-eclampsia resolved. The surviving twin initially had absent end diastolic flow, which resolved after the demise. A healthy 1935-g neonate with Apgar 9/9 was delivered at 34 weeks. Antenatal resolution of pre-eclampsia is extremely rare and resolution of superimposed pre-eclampsia has not, to our knowledge, been reported.

  4. Development of a prototype apparatus visualizing on a screen the gamma sources superimposed on the image of the vision field

    Energy Technology Data Exchange (ETDEWEB)

    Imbard, G.; Lemaire, J.E. [CEA Centre d`Etudes de la Vallee du Rhone, 30 - Marcoule (France). Dept. d`Exploitation du Retraitement et de Demantelement; Carcreff, H.; Marchand, L.; Thellier, G. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. des Reacteurs Experimentaux

    1994-12-31

    Mapping the gamma activity of irradiating zones is often an important prerequisite in dismantling nuclear facilities. The operation is necessary to define a suitable decommissioning strategy before any work begins; it is also required during the procedure to measure the residual activity wherever dose rates are too high to allow human intervention. This report summarizes the work carried out under CEC contract FIED-0055, covering a prototype imaging system designed to display radioactive sources superimposed in real time over a visible light image on a video monitor. This project was developed from an earlier off-line system. The gamma photons are collimated by a double cone system. The imaging system comprises a transparent scintillator bonded to the fiber-optic window of an ultrasensitive camera. The camera was miniaturized to meet specification requirements: with its radiological shielding, the gamma camera weighs 40 kg and is 120 mm in diameter. The processing system is compatible with a realtime camera, and small enough for use at any nuclear. The point-source angular resolution is 1.4 deg. for {sup 60} Co and 0.8 deg. for {sup 137} Cs. The dose rate sensitivity limit is approximately 0.01 mGy.h{sup -1}. Process reliability was confirmed by tests in a high-level radio-metallurgy cell at actual decommissioning site. (authors). 7 figs.

  5. Experimental results of superimposing 9.9 GHz extraordinary mode microwaves on 2.45 GHz ECRIS plasma

    Energy Technology Data Exchange (ETDEWEB)

    Nishiokada, Takuya, E-mail: nishiokada@nf.eie.eng.osaka-u.ac.jp; Nagaya, Tomoki; Hagino, Shogo; Otsuka, Takuro; Sato, Fuminobu; Kato, Yushi [Division of Electrical, Electronic, and Information Engineering, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita-shi, Osaka 565-0871 (Japan); Muramatsu, Masayuki; Kitagawa, Atsushi [National Institute of Radiological Sciences (NIRS), 4-9-1 Anagawa, Inage-ku, Chiba-shi, Chiba 263-855 (Japan)

    2016-02-15

    Efficient production of multicharged ions has been investigated on the tandem-type ECRIS in Osaka University. According to the consideration of the accessibility conditions of microwaves to resonance and cutoff regions, it was suggested that the upper hybrid resonance (UHR) heating contributed to enhancement of ion beam intensity. In order to enhance multicharged ion beams efficiently, injecting higher frequency microwave with extraordinary (X-mode) toward UHR region has been tried. In this study, 2.45 GHz frequency microwaves are used for conventional ECR discharge, and 9.9 GHz frequency microwaves with X-mode are superimposed for UHR heating. The effects of additive microwave injection are investigated experimentally in terms of plasma parameters and electron energy distribution function (EEDF) measured by Langmuir probe and ion beam current. As the results show, it is confirmed that the electrons in the high energy region are affected by 9.9 GHz X-mode microwave injection from the detailed analysis of EEDF.

  6. Delirium superimposed on dementia: a survey of delirium specialists shows a lack of consensus in clinical practice and research studies.

    Science.gov (United States)

    Richardson, Sarah; Teodorczuk, Andrew; Bellelli, Giuseppe; Davis, Daniel H J; Neufeld, Karin J; Kamholz, Barbara A; Trabucchi, Marco; MacLullich, Alasdair M J; Morandi, Alessandro

    2016-05-01

    Despite advances in delirium knowledge and the publication of best practice guidelines, uncertainties exist regarding assessment of Delirium Superimposed on Dementia (DSD). An international survey of delirium specialists was undertaken to evaluate current practice. Invitations to participate in an online survey were distributed by email among members of four international delirium associations with additional publication on their websites. The survey covered the assessment and diagnosis of DSD in clinical practice and research studies. Questions were structured around current practice and attitudes. The 205 responders were mostly confident that they could detect DSD with 60% rating their confidence at 7 or above on a likert scale of 0 (none) to 10 (excellent). Seventy-six percent felt that Dementia with Lewy Bodies (DLB) was the most challenging dementia subtype in which to diagnose DSD. Several scales were used to assess for the presence of DSD including the Confusion Assessment Method (CAM) (54%), DSM-5 criteria (25%) and CAM-ICU (15%). Responders stated that attention (71%), fluctuation in cognitive status (65%), and arousability (41%) were the most clinically useful features to assess when diagnosing DSD. Motor fluctuations were also deemed important but 61% had no specific test to monitor these. The largest survey of DSD practice to date demonstrates that despite good levels of confidence in recognizing DSD, there exists a lack of consensus concerning assessment and diagnosis globally. These findings suggest the need for the development of more research leading to precise diagnostic criteria and comprehensive guidelines regarding the assessment and diagnosis of DSD.

  7. Feasibility study of monitoring of plasma etching chamber conditions using superimposed high-frequency signals on rf power transmission line.

    Science.gov (United States)

    Kasashima, Y; Uesugi, F

    2015-10-01

    An in situ monitoring system that can detect changes in the conditions of a plasma etching chamber has been developed. In the system, low-intensity high-frequency signals are superimposed on the rf power transmission line used for generating plasma. The system measures reflected high-frequency signals and detects the change in their frequency characteristics. The results indicate that the system detects the changes in the conditions in etching chambers caused by the changes in the electrode gap and the inner wall condition and demonstrate the effectiveness of the system. The system can easily be retrofitted to mass-production equipment and it can be used with or without plasma discharge. Therefore, our system is suitable for in situ monitoring of mass-production plasma etching chambers. The system is expected to contribute to development of predictive maintenance, which monitors films deposited on the inner wall of the chamber and prevents equipment faults caused by misalignment of chamber parts in mass-production equipment.

  8. Novel Au/La-SrTiO3 microspheres: superimposed effect of gold nanoparticles and lanthanum doping in photocatalysis.

    Science.gov (United States)

    Wang, Guannan; Wang, Pei; Luo, He-Kuan; Hor, T S Andy

    2014-07-01

    Novel multielement Au/La-SrTiO(3) microspheres were synthesized by a solvothermal method using monodisperse gold and La-SrTiO(3) nanocrystals as building blocks. The porous Au/La-SrTiO(3) microspheres had a large surface area of 94.6 m(2)  g(-1). The stable confined Au nanoparticles demonstrated strong surface plasmon resonance effect, leading to enhanced absorption in a broad UV/Vis/NIR range. Doping of rare-earth metal La also broadened the absorption band to the visible region. Both the conduction and valence bands of Au/La-SrTiO(3) microspheres thus show favorable potential for proton reduction under visible light. The superimposed effect of Au nanoparticles and La doping in Au/La-SrTiO(3) microspheres led to high photocurrent density in photoelectrochemical water splitting and good photocatalytic activity in photodegradation of rhodamine B. The photocatalytic activities are in the order of the following: Au/La-SrTiO(3) microspheres>Au/SrTiO(3) microspheres>La-SrTiO(3) microspheres>SrTiO(3) microspheres.

  9. High-speed observation of bubble cloud generation near a rigid wall by second-harmonic superimposed ultrasound.

    Science.gov (United States)

    Yoshizawa, Shin; Yasuda, Jun; Umemura, Shin-ichiro

    2013-08-01

    Cavitation bubbles are known to accelerate therapeutic effects of ultrasound. Although negative acoustic pressure is the principle factor of cavitation, positive acoustic pressure has a role for bubble cloud formation at a high intensity of focused ultrasound when cavitation bubbles provide pressure release surfaces converting the pressure from highly positive to negative. In this study, the second-harmonic was superimposed onto the fundamental acoustic pressure to emphasize either peak positive or negative pressure. The peak negative and positive pressure emphasized waves were focused on a surface of an aluminum block. Cavitation bubbles induced near the block were observed with a high-speed camera by backlight and the size of the cavitation generation region was measured from the high-speed images. The negative pressure emphasized waves showed an advantage in cavitation inception over the positive pressure emphasized waves. In the sequence of the negative pressure emphasized waves immediately followed by the positive pressure emphasized waves, cavitation bubbles were generated on the block by the former waves and the cavitation region were expanded toward the transducer in the latter waves with high reproducibility. The sequence demonstrated its potential usefulness in enhancing the effects of therapeutic ultrasound at a high acoustic intensity.

  10. Normal Spectral Emissivity Measurement of Molten Cu-Co Alloy Using an Electromagnetic Levitator Superimposed with a Static Magnetic Field

    Science.gov (United States)

    Ueno, Shoya; Nakamura, Yuki; Sugioka, Ken-Ichi; Kubo, Masaki; Tsukada, Takao; Uchikoshi, Masahito; Fukuyama, Hiroyuki

    2017-02-01

    The normal spectral emissivity of molten Cu-Co alloy with different compositions was measured in the wavelength range of 780 nm to 920 nm and in the temperature range of 1430 K to 1770 K including the undercooled condition by an electromagnetic levitator superimposed with a static magnetic field. The emissivity was determined as the ratio of the radiance from a levitated molten Cu-Co droplet measured by a spectrometer to the radiance from a blackbody calculated by Planck's law at a given temperature, where a static magnetic field of 2.5 T to 4.5 T was applied to the levitated droplet to suppress the surface oscillation and translational motion of the sample. We found little temperature dependence of the normal spectral emissivity of molten Cu-Co alloy. Concerning the composition dependence, the emissivity decreased markedly above 80 at%Cu and reached that of pure Cu, although its dependence was low between 20 at%Cu and 80 at%Cu. In addition, this composition dependence of the emissivity of molten Cu-Co alloy can be explained well by the Drude free-electron model.

  11. Threatening “the Good Order”: West Meets East in Cecil B. DeMille’s <em>The Cheatem> and John Updike’s <em>Terrorist>

    Directory of Open Access Journals (Sweden)

    Bradley M. Freeman

    2011-12-01

    Full Text Available

    Despite almost a hundred years of separation, both Cecil B. DeMille’s film <em>The Cheatem> (1915 and John Updike’s novel <em>Terrorist> (2006 deploy a clear-cut territorial divide between Western and Eastern spaces in order to envision a unified American space. These narratives superimpose a “natural” division on these historically opposed spaces and thereby suggest that any contact between these spaces will have dangerous consequences. These consequences include the potential dissolution and eventual destruction of American productivity, surveillance, and territorial integrity. DeMille’s film and Updike’s novel represent America as a nation-state that must be protected from the East. In 1915, <em>The Cheatem> warned against an interracial America and the upsurge in immigration that characterized the turn of the century. Nearly a century later, <em>Terrorist> presupposes an interracial America but still constructs an East that threatens the security of America. While registering the particular concerns of two distinct historical moments, these narratives represent a larger attempt in American aesthetics to imagine an East that jeopardizes the utopian possibilities of an overly idealized American space.

  12. Protective and super-imposing effects of Estradiol , Breviscapini, Lumbrokinase In focal cerebral ischemic-reperfusion injury on rats

    Institute of Scientific and Technical Information of China (English)

    Shang huiFang; Luo ZuMing

    2000-01-01

    Baekgrouad: Postmenopausal estrogen replacement therapy is always associated with a decrease in risk of stroke incidence and mortality. The breviscapini and lumbrokinase can protect brain from ischemic injury..Experiments in animal models suggest estradiol can protect brain from ischemic injury. But we know little about the mechanism of brain protection role of estradiol. Espectically we don't know if estrodiol plus other brain protective drugs such as breviscapini and lumbrokinase have superimposing protection. Objective: To study protective function and its mechanism of estradio breviscapini and lumbrokinase after cerebral ischemic reperfusion tn overiectimiaed rat. Methods: We made the local ischemic repenfusion model with thread emgolism of right middle cerebral artery (MCA) of young female SD rars which werc bilaterally ovariectomized two weeks ago were used. These rats were randomized into sham-operated group, control group, estrodiol group, brevisacapini group, 10 SD rats each group. We admistrated each group with reseponsed treatment when rats were subjected to half an hour of MCAO. MCA were oecluded 2 hours and followed by 70 hours of reperfusion. Sham-poerated group were exposed cervical common artery and weren't occluded MCA. The rats were killed at 72 hours. The observed patameters each group listed: 1) The neurological deficit scores were made after MCAO 2 hours and bcforc killed. 2) Each group excluded sham operaated group were caculaled cerebral infarct volume ratio and edema volume with stereological microscoppe. 3) The level of Nitrc oxide (NO) in serum were determined with nitrate redutase method. 4) The level of Interlukin-I (IL-1) and tumor necrosis factot (TNF) were determined by biological activity method. 5) Ultrastructure of neuron were observed with electron microscope. All the rcsults from different groups were compared with each other. The drugs identified effictive in formcr study plus estradiot wcre admistratcd to rats to obscrvcd

  13. Protective and super-imposing effects of Estradiol , Breviscapini, Lumbrokinase In focal cerebral ischemic-reperfusion injury on rats

    Institute of Scientific and Technical Information of China (English)

    Shang huiFang; Luo ZuMing

    2000-01-01

    Baekgrouad: Postmenopausal estrogen replacement therapy is always associated with a decrease in risk of stroke incidence and mortality. The breviscapini and lumbrokinase can protect brain from ischemic injury..Experiments in animal models suggest estradiol can protect brain from ischemic injury. But we know little about the mechanism of brain protection role of estradiol. Espectically we don't know if estrodiol plus other brain protective drugs such as breviscapini and lumbrokinase have superimposing protection. Objective: To study protective function and its mechanism of estradio breviscapini and lumbrokinase after cerebral ischemic reperfusion tn overiectimiaed rat. Methods: We made the local ischemic repenfusion model with thread emgolism of right middle cerebral artery (MCA) of young female SD rars which werc bilaterally ovariectomized two weeks ago were used. These rats were randomized into sham-operated group, control group, estrodiol group, brevisacapini group, 10 SD rats each group. We admistrated each group with reseponsed treatment when rats were subjected to half an hour of MCAO. MCA were oecluded 2 hours and followed by 70 hours of reperfusion. Sham-poerated group were exposed cervical common artery and weren't occluded MCA. The rats were killed at 72 hours. The observed patameters each group listed: 1) The neurological deficit scores were made after MCAO 2 hours and bcforc killed. 2) Each group excluded sham operaated group were caculaled cerebral infarct volume ratio and edema volume with stereological microscoppe. 3) The level of Nitrc oxide (NO) in serum were determined with nitrate redutase method. 4) The level of Interlukin-I (IL-1) and tumor necrosis factot (TNF) were determined by biological activity method. 5) Ultrastructure of neuron were observed with electron microscope. All the rcsults from different groups were compared with each other. The drugs identified effictive in formcr study plus estradiot wcre admistratcd to rats to obscrvcd

  14. Frequency dependence of lung volume changes during superimposed high-frequency jet ventilation and high-frequency jet ventilation.

    Science.gov (United States)

    Sütterlin, R; Priori, R; Larsson, A; LoMauro, A; Frykholm, P; Aliverti, A

    2014-01-01

    Superimposed high-frequency jet ventilation (SHFJV) has proved to be safe and effective in clinical practice. However, it is unclear which frequency range optimizes ventilation and gas exchange. The aim of this study was to systematically compare high-frequency jet ventilation (HFJV) with HFJV by assessing chest wall volume variations (ΔEEV(CW)) and gas exchange in relation to variable high frequency. SHFJV or HFJV were used alternatively to ventilate the lungs of 10 anaesthetized pigs (21-25 kg). The low-frequency component was kept at 16 min(-1) in SHFJV. In both modes, high frequencies ranging from 100 to 1000 min(-1) were applied in random order and ventilation was maintained for 5 min in all modalities. Chest wall volume variations were obtained using opto-electronic plethysmography. Airway pressures and arterial blood gases were measured repeatedly. SHFJV increased ΔEEV(CW) compared with HFJV; the difference ranged from 43 to 68 ml. Tidal volume (V(T)) was always >240 ml during SHFJV whereas during HFJV ranged from 92 ml at the ventilation frequency of 100 min(-1) to negligible values at frequencies >300 min(-1). We observed similar patterns for Pa(O₂) and Pa(CO₂). SHFJV provided generally higher, frequency-independent oxygenation (Pa(O₂) at least 32.0 kPa) and CO₂ removal (Pa(CO₂) ∼5.5 kPa), whereas HFJV led to hypoxia and hypercarbia at higher rates (Pa(O₂) 10 kPa at f(HF)>300 min(-1)). In a porcine model, SHFJV was more effective in increasing end-expiratory volume than single-frequency HFJV, but both modes may provide adequate ventilation in the absence of airway obstruction and respiratory disease, except for HFJV at frequencies ≥300 min(-1).

  15. Synergistic and Superimposed Effect of Bone Marrow-Derived Mesenchymal Stem Cells Combined with Fasudil in Experimental Autoimmune Encephalomyelitis.

    Science.gov (United States)

    Yu, Jing-Wen; Li, Yan-Hua; Song, Guo-Bin; Yu, Jie-Zhong; Liu, Chun-Yun; Liu, Jian-Chun; Zhang, Hai-Fei; Yang, Wan-Fang; Wang, Qing; Yan, Ya-Ping; Xiao, Bao-Guo; Ma, Cun-Gen

    2016-12-01

    Bone marrow-derived mesenchymal stem cells (MSCs) are the ideal transplanted cells of cellular therapy for promoting neuroprotection and neurorestoration. However, the optimization of transplanted cells and the improvement of microenvironment around implanted cells are still two critical challenges for enhancing therapeutic effect. In the current study, we observed the therapeutic potential of MSCs combined with Fasudil in mouse model of experimental autoimmune encephalomyelitis (EAE) and explored possible mechanisms of action. The results clearly show that combined intervention of MSCs and Fasudil further reduced the severity of EAE compared with MSCs or Fasudil alone, indicating a synergistic and superimposed effect in treating EAE. The addition of Fasudil inhibited MSC-induced inflammatory signaling TLR-4/MyD88 and inflammatory molecule IFN-γ, IL-1β, and TNF-α but did not convert M1 microglia to M2 phenotype. The delivery of MSCs enhanced the expression of glial cell-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) compared with that of Fasudil. Importantly, combined intervention of MSCs and Fasudil further increased the expression of BDNF and GDNF compared with the delivery of MSCs alone, indicating that combined intervention of MSCs and Fasudil synergistically contributes to the expression of neurotrophic factors which should be related to the expression of increased galactocerebroside (GalC) compared with mice treated with Fasudil and MSCs alone. However, a lot of investigation is warranted to further elucidate the cross talk of MSCs and Fasudil in the therapeutic potential of EAE/multiple sclerosis.

  16. Dependence of the frequency spectrum of small amplitude vibrations superimposed on finite deformations of a nonlinear, cylindrical elastic body on residual stress

    KAUST Repository

    Gorb, Yuliya

    2010-11-01

    We model and analyze the response of nonlinear, residually stressed elastic bodies subjected to small amplitude vibrations superimposed upon large deformations. The problem derives from modeling the use of intravascular ultrasound (IVUS) imaging to interrogate atherosclerotic plaques in vivo in large arteries. The goal of this investigation is twofold: (i) introduce a modeling framework for residual stress that unlike traditional Fung type classical opening angle models may be used for a diseased artery, and (ii) investigate the sensitivity of the spectra of small amplitude high frequency time harmonic vibrations superimposed on a large deformation to the details of the residual stress stored in arteries through a numerical simulation using physiologic parameter values under both low and high blood pressure loadings. The modeling framework also points the way towards an inverse problem using IVUS techniques to estimate residual stress in healthy and diseased arteries. © 2010 Elsevier Ltd. All rights reserved.

  17. Accelerating Oil and Gas Exploration in Western China by Studies of Formations of Hydrocarbon Accumulations in Superimposed Basins——A Preface

    Institute of Scientific and Technical Information of China (English)

    PANG Xiongqi

    2010-01-01

    @@ The superimposed basins in the western region of China are a hot research topic for earth scientists home and abroad for their vast area and rich oil and gas resources.Their complex geological conditions and resultant great exploration difficulties have received much attention of the scientists.This issue presents the advances of several scholars in their long-term research on the mechanisms of oil and gas accumulation and the patterns of oil and gas distribution.These studies are part of the National 973Project entitled"Mechanism of Oil and Gas Accumulation and Patterns of Oil and Gas Distribution in Typical Superimposed Basins in the Western Region of China(no.2006CB202300)",which is funded by the Chinese Ministry of Science and Technology.

  18. Investigation of the Impact of a Heinrich-Event-like Abrupt Event Superimposed Onto the RCP 8.5 Scenario

    Science.gov (United States)

    Defrance, D.; Ramstein, G.; Dumas, C.; Charbit, S.

    2014-12-01

    The CMIP5/IPCC (AR5) projections of climate change showed the temperatures should increase by between 1.3 °C and 4.4 °C by 2100 and the sea level rise between 26 cm and 82 cm on average. Superimposed on these climatic and hydrologic trends associated with the RCP 8.5 most pessimistic scenario, it is important to investigate the possible effect of an abrupt event like an ice-sheet surge. This is first justified by the recent collapse of the Larsen B ice shelf which illustrates that a non-linear response of the cryosphere may occur in a warming world. Furthermore, in glacial periods, ice-sheets have been unstable and huge surges of icebergs did occur and deeply modified the climate. The aim of this presentation is to show the hypothetical climatic consequences of such a Heinrich-type event on future climate change. To achieve this goal, 3 scenarios of rapid ice-sheet deglaciation have been designed, corresponding to an additional sea level rise of around 3 m : - S1 corresponds to a contribution from Greenland only; - S2 from West-Antarctica only; - S3 from both ice-sheets. We use the global atmosphere-ocean general circulation model (OAGCM) IPSL-CM5A-LR. The freshwater perturbation is applied near the ice-sheet(s) during 20 years from 2050 to 2070 during an RCP8.5 perturbation. The RCP8.5 scenario is then continued until 2100 (without freshwater). For these types of scenarios, previous experiments for paleoclimatic cases help us diagnose the most vulnerable areas. The North Atlantic and the collapse of thermohaline circulation is one key issue, but far field teleconnections with the Asian monsoon will also be explored. We will investigate the timing and amplitude of the climate impacts due to the perturbations, which may be quite different in our 3 scenarios. These abrupt events consequences can be important for the populations and the consideration of rapid changes should improve the reliability of IPCC predictions.

  19. Reference Gene Selection in the Desert Plant <em>Eremosparton songoricuem>m>

    Directory of Open Access Journals (Sweden)

    Dao-Yuan Zhang

    2012-06-01

    Full Text Available <em>Eremosparton songoricum em>(Litv. Vass. (<em>E. songoricumem> is a rare and extremely drought-tolerant desert plant that holds promise as a model organism for the identification of genes associated with water deficit stress. Here, we cloned and evaluated the expression of eight candidate reference genes using quantitative real-time reverse transcriptase polymerase chain reactions. The expression of these candidate reference genes was analyzed in a diverse set of 20 samples including various <em>E. songoricumem> plant tissues exposed to multiple environmental stresses. GeNorm analysis indicated that expression stability varied between the reference genes in the different experimental conditions, but the two most stable reference genes were sufficient for normalization in most conditions.<em> EsEFem> and <em>Esα-TUB> were sufficient for various stress conditions, <em>EsEF> and <em>EsACT> were suitable for samples of differing germination stages, and <em>EsGAPDH>and <em>Es>UBQ em>were most stable across multiple adult tissue samples. The <em>Es18Sem> gene was unsuitable as a reference gene in our analysis. In addition, the expression level of the drought-stress related transcription factor <em>EsDREB2em>> em>verified the utility of<em> E. songoricumem> reference genes and indicated that no single gene was adequate for normalization on its own. This is the first systematic report on the selection of reference genes in <em>E. songoricumem>, and these data will facilitate future work on gene expression in this species.

  20. Geospatial Analysis of Pediatric EMS Run Density and Endotracheal Intubation

    Directory of Open Access Journals (Sweden)

    Matthew Hansen

    2016-09-01

    Full Text Available Introduction: The association between geographic factors, including transport distance, and pediatric emergency medical services (EMS run clustering on out-of-hospital pediatric endotracheal intubation is unclear. The objective of this study was to determine if endotracheal intubation procedures are more likely to occur at greater distances from the hospital and near clusters of pediatric calls. Methods: This was a retrospective observational study including all EMS runs for patients less than 18 years of age from 2008 to 2014 in a geographically large and diverse Oregon county that includes densely populated urban areas near Portland and remote rural areas. We geocoded scene addresses using the automated address locator created in the cloud-based mapping platform ArcGIS, supplemented with manual address geocoding for remaining cases. We then use the Getis-Ord Gi spatial statistic feature in ArcGIS to map statistically significant spatial clusters (hot spots of pediatric EMS runs throughout the county. We then superimposed all intubation procedures performed during the study period on maps of pediatric EMS-run hot spots, pediatric population density, fire stations, and hospitals. We also performed multivariable logistic regression to determine if distance traveled to the hospital was associated with intubation after controlling for several confounding variables. Results: We identified a total of 7,797 pediatric EMS runs during the study period and 38 endotracheal intubations. In univariate analysis we found that patients who were intubated were similar to those who were not in gender and whether or not they were transported to a children’s hospital. Intubated patients tended to be transported shorter distances and were older than non-intubated patients. Increased distance from the hospital was associated with reduced odds of intubation after controlling for age, sex, scene location, and trauma system entry status in a multivariate logistic

  1. Synthesis, Crystal Structure and Luminescent Property of Cd (II Complex with <em>N-Benzenesulphonyl-L>-leucine

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    Xishi Tai

    2012-09-01

    Full Text Available A new trinuclear Cd (II complex [Cd3(L6(2,2-bipyridine3] [L =<em> Nem>-phenylsulfonyl-L>-leucinato] has been synthesized and characterized by elemental analysis, IR and X-ray single crystal diffraction analysis. The results show that the complex belongs to the orthorhombic, space group<em> Pem>212121 with<em> aem> = 16.877(3 Å, <em>b> em>= 22.875(5 Å, <em>c em>= 29.495(6 Å, <em>α> em>= <emem>= <emem>= 90°, <em>V> em>= 11387(4 Å3, <em>Z> em>= 4, <em>Dc>= 1.416 μg·m−3, <emem>= 0.737 mm−1, <em>F> em>(000 = 4992, and final <em>R>1 = 0.0390, <em>ωR>2 = 0.0989. The complex comprises two seven-coordinated Cd (II atoms, with a N2O5 distorted pengonal bipyramidal coordination environment and a six-coordinated Cd (II atom, with a N2O4 distorted octahedral coordination environment. The molecules form one dimensional chain structure by the interaction of bridged carboxylato groups, hydrogen bonds and p-p interaction of 2,2-bipyridine. The luminescent properties of the Cd (II complex and <em>N-Benzenesulphonyl-L>-leucine in solid and in CH3OH solution also have been investigated.

  2. <em>α>-Glucosidase Inhibitory Constituents from <em>Acanthopanax senticosusem> Harm Leaves

    Directory of Open Access Journals (Sweden)

    Hai-Xue Kuang

    2012-05-01

    Full Text Available A new triterpene glycoside, 3-<em>O-[(α>-L-rhamnopyranosyl(1→2]-[<em>β>-D-glucuronopyranosyl-6-<em>O>-methyl ester]-olean-12-ene-28-olic acid (1 and a new indole alkaloid, 5-methoxy-2-oxoindolin-3-acetic acid methyl ester (5 were isolated from the leaves of <em>Acanthopanax senticosusem> Harms along with six known compounds. The structures of the new compounds were determined by means of 2D-NMR experiments and chemical methods. All the isolated compounds were evaluated for their glycosidase inhibition activities and compound 6 showed significant <em>α>-glucosidase inhibition activity.

  3. A numerical study of the three-dimensional structure of the Taylor-Couette flow in eccentric configuration with superimposed cross flow

    Energy Technology Data Exchange (ETDEWEB)

    Scurtu, Nicoleta; Egbers, Christoph [Brandenburgische Technische Universitaet (BTU), Cottbus (Germany); Stuecke, Peter [Westsaechsische Hochschule (WHZ), Zwickau (Germany)], E-mail: scurtu@tu-cottbus.de

    2008-11-01

    The eccentric small gap Taylor-Couette system with rotating inner cylinder and fixed outer cylinder is investigated numerically. The main flow fields were examined and the transition region from the laminar Couette-flow to the Taylor-vortex-flow in different eccentric arrangements of the cylinders. The effect of the eccentricity on flow patterns was studied for different values of the eccentricity between 0 and 0.75 in relation to the mean gap. This flow was further disturbed by the superimposed cross flow entering into the gap through the feed hole with a cross flow rate of 0.1 of the circumferential flow rate. Hence, more complex three dimensional flow structures evolved in the cylinders' gap, especially in the vicinity of the feed hole.

  4. Three New Myrsinol Diterpenes from <em>Euphorbia proliferaem> and Their Neuroprotective Activities

    Directory of Open Access Journals (Sweden)

    Yuanqiang Guo

    2012-08-01

    Full Text Available Three new myrsinol diterpenes were isolated from the roots of<em> em>>Euphorbia proliferaem>. Their structures were elucidated as 2<em>α-O>-isobutyryl-3<em>β>,5<em>α>,7<em>β>,10,15<em>β-penta-O>-acetyl-14<em>α-O>-benzoyl-10,18-dihydromyrsinol (1, 2<em>α-O>-isobutyryl-3<em>β-O>-propion-yl-5<em>α>,7<em>β>,10,15<em>β-tetra-O>-acetyl-10,18-dihydromyrsinol (2, and 2<em>α>,14<em>α-di-O>-benzoyl-3<em>β>,5<em>α>,7<em>β>,10,15<em>β-penta-O>-acetyl-10,18-dihydromyrsinol (3 on the basis of spectroscopic data analyses (IR, ESI-MS, HR-ESI-MS, and 1D and 2D NMR. Their neuroprotective activities were evaluated and compounds 1 and 2 showed neuroprotective effects against MPP+-induced neuronal cell death in SH-SY5Y cells.

  5. Neonatal Phosphate Nutrition Alters <em>in em>Vivo> and <em>in em>Vitro> Satellite Cell Activity in Pigs

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    Chad H. Stahl

    2012-05-01

    Full Text Available Satellite cell activity is necessary for postnatal skeletal muscle growth. Severe phosphate (PO4 deficiency can alter satellite cell activity, however the role of neonatal PO4 nutrition on satellite cell biology remains obscure. Twenty-one piglets (1 day of age, 1.8 ± 0.2 kg BW were pair-fed liquid diets that were either PO4 adequate (0.9% total P, supra-adequate (1.2% total P in PO4 requirement or deficient (0.7% total P in PO4 content for 12 days. Body weight was recorded daily and blood samples collected every 6 days. At day 12, pigs were orally dosed with BrdU and 12 h later, satellite cells were isolated. Satellite cells were also cultured <em>in vitroem> for 7 days to determine if PO4 nutrition alters their ability to proceed through their myogenic lineage. Dietary PO4 deficiency resulted in reduced (<em>P> < 0.05 sera PO4 and parathyroid hormone (PTH concentrations, while supra-adequate dietary PO4 improved (<em>P> < 0.05 feed conversion efficiency as compared to the PO4 adequate group. <em>In vivoem> satellite cell proliferation was reduced (<em>P> < 0.05 among the PO4 deficient pigs, and these cells had altered <em>in vitroem> expression of markers of myogenic progression. Further work to better understand early nutritional programming of satellite cells and the potential benefits of emphasizing early PO4 nutrition for future lean growth potential is warranted.

  6. 基于视频叠加的心理暗示%Information producing of psychological suggestion based on video superimposing

    Institute of Scientific and Technical Information of China (English)

    郭小一; 老松杨; 张国华

    2012-01-01

    针对未来心理战民意制约、隐式作战等趋势,提出了基于视频叠加的心理暗示(PSBVS)的构想.分析了PSBVS媒体基础、理论基础和方法基础,为实现信息有效编码进而有效影响受众心理,围绕暗示信息生成构建了一个基本的理论框架.研究了主体编码过程、暗示信息视频语义层次结构、受众心理效应过程以及三者之间的关联,针对感知特征层建立了视频叠加的认知参数模型,对参数设置进行了初步分析,提出了视频叠加暗示信息的心理效果模型,力图为信息内容和形式的确定提供一定的依据和支持.除了心理战,PSBVS在广告营销、医疗和教育等领域都具有重要的应用价值.%An idea of psychological suggestion based on video superimposing (PSBVS) was proposed for the trend of public-opinion restriction and covert operation in future psywar. The media basis, theory basis and method basis of PSBVS were analyzed firstly. Then, in order to encode information effectively and impact the psychology of psywar object successfully, a theory frame was established on suggestive information producing. The information coding process, video hiberarchy, and psychological effectiveness process were researched systemically, together with the relationship among them. The cognitive parameter model of video superimposing was constructed for perceptive-feature-level. An effect evaluation model of suggestive information was proposed, which can provide a guidance and feedback to parameter set. A theoretical support was provided for decision of information content and form. Besides psychology warfare, PSBVS has a significant applying value in fields such as commerce advertising, medicare and education.

  7. Constituents from <em>Vigna em>vexillata> and Their Anti-Inflammatory Activity

    Directory of Open Access Journals (Sweden)

    Guo-Feng Chen

    2012-08-01

    Full Text Available The seeds of <em>Vigna em>genus are important food resources and there have already been many reports regarding their bioactivities. In our preliminary bioassay, the chloroform layer of methanol extracts of<em> V. vexillata em>demonstrated significant anti-inflammatory bioactivity. Therefore, the present research is aimed to purify and identify the anti-inflammatory principles of <em>V. vexillataem>. One new sterol (1 and two new isoflavones (2,3 were reported from the natural sources for the first time and their chemical structures were determined by the spectroscopic and mass spectrometric analyses. In addition, 37 known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. Among the isolates, daidzein (23, abscisic acid (25, and quercetin (40 displayed the most significant inhibition of superoxide anion generation and elastase release.

  8. Oxygen availability and distance to surface environments determine community composition and abundance of ammonia-oxidizing prokaroytes in two superimposed pristine limestone aquifers in the Hainich region, Germany.

    Science.gov (United States)

    Opitz, Sebastian; Küsel, Kirsten; Spott, Oliver; Totsche, Kai Uwe; Herrmann, Martina

    2014-10-01

    We followed the abundance and compared the diversity of ammonia-oxidizing archaea (AOA) and bacteria (AOB) in the groundwater of two superimposed pristine limestone aquifers located in the Hainich region (Thuringia, Germany) over 22 months. Groundwater obtained from the upper aquifer (12 m depth) was characterized by low oxygen saturation (0-20%) and low nitrate concentrations (0-20 μM), contrasting with 50-80% oxygen saturation and 40-200 μM nitrate in the lower aquifer (48 m and 88 m depth). Quantitative PCR targeting bacterial and archaeal amoA and 16S rRNA genes suggested a much higher ammonia oxidizer fraction in the lower aquifer (0.4-7.8%) compared with the upper aquifer (0.01-0.29%). In both aquifers, AOB communities were dominated by one phylotype related to Nitrosomonas ureae, while AOA communities were more diverse. Multivariate analysis of amoA DGGE profiles revealed a stronger temporal variation of AOA and AOB community composition in the upper aquifer, pointing to a stronger influence of surface environments. Parallel fluctuations of AOA, AOB, and total microbial abundance suggested that hydrological factors (heavy rain falls, snow melt) rather than specific physicochemical parameters were responsible for the observed community dynamics.

  9. Research on the Reasonable Spacing of Holes in Gas Drainage along Coal Seams in Consideration of the Superimposed Effect of Drainage

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    Li Bo

    2016-02-01

    Full Text Available o determine the reasonable spacing of holes for gas drainage, an experimental study was conducted on the effective influence radius of drilling hole through the pressure drop method based on the actual condition of coal seams. The coal seam that contains gas is regarded as elastic-plastic dual media. The governing equation of gas transport is established by analyzing the different flow forms of gas in the pore and fissure systems as well as by considering the mass exchange capacity in the pore-fissure system. The equation is embedded into COMSOL Multiphysics (COMSOL software to simulate the gas drainage effect further by drilling along a coal seam under a 3-D space. Upon confirming the effective radius and drainage influence radius of a single pore, the holes for gas drainage can be reasonably spaced along the coal seam by analyzing the change features of coal permeability around the borehole and the functional mechanism of the superimposed effect of drainage, namely, 2r≤L≤R. The study results can reliably guide practical gas drainage theoretically and can also effectively lower the cost of gas drainage as well as ensure the safe production in mines.

  10. Neuro-fuzzy computing for vibration-based damage localization and severity estimation in an experimental wind turbine blade with superimposed operational effects

    Science.gov (United States)

    Hoell, Simon; Omenzetter, Piotr

    2016-04-01

    Fueled by increasing demand for carbon neutral energy, erections of ever larger wind turbines (WTs), with WT blades (WTBs) with higher flexibilities and lower buckling capacities lead to increasing operation and maintenance costs. This can be counteracted with efficient structural health monitoring (SHM), which allows scheduling maintenance actions according to the structural state and preventing dramatic failures. The present study proposes a novel multi-step approach for vibration-based structural damage localization and severity estimation for application in operating WTs. First, partial autocorrelation coefficients (PACCs) are estimated from vibrational responses. Second, principal component analysis is applied to PACCs from the healthy structure in order to calculate scores. Then, the scores are ranked with respect to their ability to differentiate different damage scenarios. This ranking information is used for constructing hierarchical adaptive neuro-fuzzy inference systems (HANFISs), where cross-validation is used to identify optimal numbers of hierarchy levels. Different HANFISs are created for the purposes of structural damage localization and severity estimation. For demonstrating the applicability of the approach, experimental data are superimposed with signals from numerical simulations to account for characteristics of operational noise. For the physical experiments, a small scale WTB is excited with a domestic fan and damage scenarios are introduced non-destructively by attaching small masses. Numerical simulations are also performed for a representative fully functional small WT operating in turbulent wind. The obtained results are promising for future applications of vibration-based SHM to facilitate improved safety and reliability of WTs at lower costs.

  11. Types, Evolution and Pool-Controlling Significance of Pool Fluid Sources in Superimposed Basins: A Case Study from Paleozoic and Mesozoic in South China

    Institute of Scientific and Technical Information of China (English)

    Xu Sihuang; Mei Lianfu; Yuan Caiping; Ma Yongsheng; Guo Tonglou

    2007-01-01

    Having multiple tectonic evolution stages, South China belongs to a superimposed basin in nature. Most marine gas pools became secondary pools. The pool fluid sources serve as the principal pool-controlling factors. On the basis of eight typical petroleum pools, the type, evolution in time-space,and the controlling of petroleum distribution of pool fluid sources are comprehensively analyzed. The main types of pool fluid sources include hydrocarbon, generated primarily and secondly from source rocks, gas cracked from crude oil, gas dissolved in water, inorganic gas, and mixed gases. In terms of evolution, the primary hydrocarbon was predominant prior to Indosinian; during Indosinian to Yenshanian the secondary gas includes gas cracked from crude oil, gas generated secondarily, gas dissolved in water, and inorganic gas dominated; during Yenshanian to Himalayan the most fluid sources were mixed gases. Controlled by pool fluid sources, the pools with mixed gas sources distributed mainly in Upper Yangtze block, especially Sichuan (四川) basin; the pools with primary hydrocarbon sources distributed in paleo-uplifts such as Jiangnan (江南), but most of these pools became fossil pools; the pools with secondary hydrocarbon source distributed in the areas covered by Cretaceous and Eogene in Middle-Lower Yangtze blocks, and Chuxiong (楚雄), Shiwandashan (十万大山), and Nanpanjiang (南盘江) basins; the pools with inorganic gas source mainly formed and distributed in tensional structure areas.

  12. Help of superimposing thoracic-abdominal images by TDN and SPECT in cancer diagnosis; Aide au diagnostique en cancerologie par superposition d`images thoraco-abdominales TDM et TEMP

    Energy Technology Data Exchange (ETDEWEB)

    Perault, C.; Schvartz, C.; Wampach, H.; Liehn, J.C.; Delisle, M.J.; Groupe de Pathologie Thyroidienne Tumorale [Institut Jean Godinot, Reims 51056 (France)

    1997-12-31

    Superimposing anatomic (TDM) and tumor specific (SPECT) tomographies facilitates tumor detection and localization. The method that we have earlier developed for pelvic tumors, has been adapted for endocrine tumors in the most deformable thorax-abdominal region. Forty, TDM and double-isotope SPECT acquisitions, comprising an osseous scintigraphy (by {sup 99m}Tc-HMDP) and tumor specific scintigraphy (by {sup 111}In - pentetreotide, {sup 131}I, {sup 131}I - MIBG) have been performed in 13 patients afflicted with medullar (5), differentiated (5), thyroid cancers or carcinoid tumors (3). The fiducial points located on the visible anatomical structures in the two modalities allow making the calculation, some times local, of the matching parameters, what leads to the superimposed images. Ten sites were validated by surgery or later imaging in 8 patients. The reproducibility and matching accuracy were checked for every patient due to the superimposed TDM images and osseous scintigraphies. The superimposed TDM images and tumoral scintigraphy have allowed to increase the reliability and accuracy, to localize the TDM- undetected tumoral sites, to determine the tissue nature of doubtful TDM interpretation and to confirm the positive TDM interpretation or to recognize non-specific scintigraphic fixation. The TDM-SPECT superposition, without external labellers, is possible in the thorax and abdomen, even when the matching accuracy is limited because of relative movement of organs due to respiration or posture. A multi-center study is under way aiming at a larger validation and clinic evaluation

  13. The Antimicrobial Efficacy of <em>Elaeis guineensisem>: Characterization, <em>in Vitroem> and <em>in Vivoem> Studies

    Directory of Open Access Journals (Sweden)

    Sreenivasan Sasidharan

    2012-04-01

    Full Text Available The urgent need to treat multi-drug resistant pathogenic microorganisms in chronically infected patients has given rise to the development of new antimicrobials from natural resources. We have tested <em>Elaeis guineensis em>Jacq> em>(Arecaceae methanol extract against a variety of bacterial, fungal and yeast strains associated with infections. Our studies have demonstrated that <em>E. guineensisem> exhibits excellent antimicrobial activity <em>in vitroem> and <em>in vivoem> against the bacterial and fungal strains tested. A marked inhibitory effect of the <em>E. guineensisem> extracts was observed against <em>C. albicansem> whereby <em>E. guineensisem> extract at ½, 1, or 2 times the MIC significantly inhibited <em>C. albicansem> growth with a noticeable drop in optical density (OD of the bacterial culture. This finding confirmed the anticandidal activity of the extract on <em>C. albicansem>. Imaging using scanning (SEM and transmission (TEM electron microscopy was done to determine the major alterations in the microstructure of the extract-treated <em>C. albicansem>. The main abnormalities noted via SEM and TEM studies were the alteration in morphology of the yeast cells. <em>In vivoem> antimicrobial activity was studies in mice that had been inoculated with <em>C. albicansem> and exhibited good anticandidal activity. The authors conclude that the extract may be used as a candidate for the development of anticandidal agent.<em> em>

  14. 叠合板式剪力墙T型、L型墙体抗震性能试验研究%EXPERIMENTAL STUDY OF SEISMIC PERFORMANCE ON T AND L TYPES SUPERIMPOSED-SLAB-SHEAR-WALLS STRUCTURE

    Institute of Scientific and Technical Information of China (English)

    张伟林; 沈小璞; 吴志新; 姚峰

    2012-01-01

    采用试验方法,研究叠合板式混凝土剪力墙T型、L型拼接墙体抗震性能。分析了叠合板式剪力墙结构体系抗震设计关键技术研究现状。对叠合板式混凝土剪力墙试件进行非线性推覆研究和非弹性动力响应分析,重点研究影响T型、L型拼接构件抗震性能的滞回曲线、骨架随线、刚度下降曲线和延性性能。研究结果表明:叠合板式剪力墙与全现浇剪力墙的抗震性能基本一致。根据试验结论,提出叠合板式混凝土剪力墙结构基于性能的抗震设计方法。编制出的地方规范已经发布并得到应用。%The seismic problem of a superimposed-slab-shear-walls structure was studied by the experimental method. The key technology of the structural seismic research on a superimposed-slab-shear-walls system was analyzed. Superimposed-slab shear walls was utilized to study the cause of nonlinear detrude-wreck and the parameters of non-elastically dynastic response, where it was focused on the analysis of the hysterics loops, skeleton loops, stiffness degrading loops and ductility of the connections (including T and L types connections) of the superimposed slab that effect the anti-seismic performance of the structure. The results show that the seismic performance of the superimposed-slab shear walls is the same as that of concrete shear walls. According to the research result, the design method of a superimposed-slab-shear-walls structure based on the anti-seismic performance is forward. The local regulation of aseismic design for a superimposed-slab-shear-walls structure has been released and is applied to engineering.

  15. Efficient Heterologous Transformation of <em>Chlamydomonas> reinhardtiiem> <em>npq2em> Mutant with the Zeaxanthin Epoxidase Gene Isolated and Characterized from<em> Chlorella zofingiensisem>

    Directory of Open Access Journals (Sweden)

    Herminia Rodríguez

    2012-09-01

    Full Text Available In the violaxanthin cycle, the violaxanthin de-epoxidase and zeaxanthin epoxidase catalyze the inter-conversion between violaxanthin and zeaxanthin in both plants and green algae. The zeaxanthin epoxidase gene from the green microalga <em>Chlorella zofingiensisem> (<em>Czzep> has been isolated<em>. em>This gene encodes a polypeptide of 596 amino acids. A single copy of <em>Czzep> has been found in the <em>C. zofingiensisem> genome by Southern blot analysis. qPCR analysis has shown that transcript levels of <em>Czzep> were increased after zeaxanthin formation under high light conditions. The functionality of <em>Czzep> gene by heterologous genetic complementation in the <em>Chlamydomonas> mutant <em>npq2em>, which lacks zeaxanthin epoxidase (ZEP activity and accumulates zeaxanthin in all conditions, was analyzed. The <em>Czzep> gene was adequately inserted in the pSI105 vector and expressed in <em>npq2em>. The positive transformants were able to efficiently convert zeaxanthin into violaxanthin, as well as to restore their maximum quantum efficiency of the PSII (Fv/Fm. These results show that <em>Chlamydomonas> can be an efficient tool for heterologous expression and metabolic engineering for biotechnological applications.

  16. Dermatoses em renais cronicos em terapia dialitica

    Directory of Open Access Journals (Sweden)

    Luis Alberto Batista Peres

    2014-03-01

    Full Text Available Objetivo: As desordens cutâneas e das mucosas são comuns em pacientes em hemodiálise a longo prazo. A diálise prolonga a expectativa de vida, dando tempo para a manifestação destas anormalidades. Os objetivos deste estudo foram avaliar a prevalência de problemas dermatológicos em pacientes com doença renal crônica (DRC em hemodiálise. Métodos: Cento e quarenta e cinco pacientes com doença renal crônica em hemodiálise foram estudados. Todos os pacientes foram completamente analisados para as alterações cutâneas, de cabelos, mucosas e unhas por um único examinador e foram coletados dados de exames laboratoriais. Os dados foram armazenados em um banco de dados do Microsolft Excel e analisados por estatística descritiva. As variáveis contínuas foram comparadas pelo teste t de Student e as variáveis categóricas utilizando o teste do qui-quadrado ou o teste Exato de Fischer, conforme adequado. Resultados: O estudo incluiu 145 pacientes, com idade média de 53,6 ± 14,7 anos, predominantemente do sexo masculino (64,1% e caucasianos (90,0%. O tempo médio de diálise foi de 43,3 ± 42,3 meses. As principais doenças subjacentes foram: hipertensão arterial em 33,8%, diabetes mellitus em 29,6% e glomerulonefrite crônica em 13,1%. As principais manifestações dermatológicas observadas foram: xerose em 109 (75,2%, equimose em 87 (60,0%, prurido em 78 (53,8% e lentigo em 33 (22,8% pacientes. Conclusão: O nosso estudo mostrou a presença de mais do que uma dermatose por paciente. As alterações cutâneas são frequentes em pacientes em diálise. Mais estudos são necessários para melhor caracterização e manejo destas dermatoses.

  17. Bioassay-Guided Isolation and Identification of Cytotoxic Compounds from <em>Gymnosperma> <em>glutinosum> Leaves

    Directory of Open Access Journals (Sweden)

    Cristina Rodríguez-Padilla

    2012-09-01

    Full Text Available Bioassay-guided fractionation of hexane extracts of<em> Gymnosperma glutinosumem> (Asteraceae leaves, collected in North Mexico, afforded the known compounds hentriacontane (1 and (+-13<em>S>,14<em>R>,15-trihydroxy-<em>ent>-labd-7-ene (2, as well as the new <em>ent>-labdane diterpene (−-13<em>S>,14<em>R>,15-trihydroxy-7-oxo-<em>ent>-labd-8(9-ene (3. In addition, D-glycero-D-galactoheptitol (4 was isolated from the methanolic extract of this plant. Their structures were established on the basis of high-field 1D- and 2D NMR methods supported by HR-MS data. The cytotoxic activity was determined by using the <em>in vitroem> L5178Y-R lymphoma murine model. Hentriacontane (1 and the new <em>ent>-labdane 3 showed weak cytotoxicity, whereas the <em>ent>-labdane 2 showed significant (<em>p> < 0.05 and concentration dependent cytotoxicity (up to 78% against L5178Y-R cells at concentrations ranging from 7.8 to 250 µg/mL.

  18. INFLUENCE OF VARIATIONS OF THE CONDUCTIVITY OF UPPER LAYER OF TWO-LAYER SAMPLE ON OF PHASE INTRODUCED ELECTROMOTIVE FORCE OF SUPERIMPOSED TRANSDUCER OF EDDY CURRENT THICKNESS METER

    Directory of Open Access Journals (Sweden)

    A. V. Chernyshev

    2017-01-01

    Full Text Available In carrying out eddy current thickness measurement of two-layer conductive objects one from the interfering factors is the presence of variations in the value of the electrical conductivity of the material of the upper layer (coating when moving from point to point on the surface of object of control or when passing from one object of control to another. The aim of this work is to evaluate the accuracy of determining the thickness of the conductive coating disposed on a conducting ferromagnetic basis, using the phase method of eddy current testing. The reason of the error is variation of the electrical conductivity of the material of coating.Determination of the error is based on calculations using known analytical expressions for the loop with current of sinusoidal form arranged over the infinite half space with a covering as a thin layer. Selected in calculating electromagnetic parameters of coating and substrate approximately correspond to the case -chromium layer on a nickel base. Calculations are performed for different frequencies of current passed through coil.It is shown that at reduction of frequency of the current passes through the coil the error is reduced. The value of the lowest possible operating frequency of the excitation current is determined by the condition of absence influence on the phase introduced into the superimposed transducer emf variations in the thickness of the basis.To reduce the indicated error it is proposed to determine, on the basis of phase method at a relatively high frequency transducer current excitation, conductivity of the material of coating. After this, at a low frequency excitation current and using phase method, the coating thickness is determined, taking into consideration the previously determined value of the conductivity of coating. Also discussed ways to improve the accuracy of phase measurements in the MHz region of the excitation current frequency. 

  19. em arquitetura e urbanismo

    Directory of Open Access Journals (Sweden)

    Ana Maria Sala Minucci Martins

    2006-01-01

    Full Text Available Está sendo desenvolvido projeto de pesquisa denominado Geometria Fractal e suas Aplicações em Arquitetura e Urbanismo, com o fito de estudar e desenvolver ferramentas analíticas e propositivas para serem aplicadas em arquitetura e urbanismo, com base em conceitos provenientes da geometria fractal.

  20. Antimicrobial Activity of Geranium Oil against Clinical Strains<em> em>of <em>Staphylococcus aureusem>

    Directory of Open Access Journals (Sweden)

    Monika Sienkiewicz

    2012-08-01

    Full Text Available The aim of this work was to investigate the antibacterial properties of geranium oil obtained from <em>Pelargonium graveolensem> Ait. (family <em>Geraniaceae>, against one standard <em>S. aureus em>strain ATCC 433000 and seventy clinical <em>S. aureusem> strains. The agar dilution method was used for assessment of bacterial growth inhibition at various concentrations of geranium oil. Susceptibility testing of the clinical strains to antibiotics was carried out using the disk-diffusion and E-test methods. The results of our experiment showed that the oil from <em>P. graveolensem> has strong activity against all of the clinical <em>S. aureusem> isolates—including multidrug resistant strains, MRSA strains and MLSB-positive strains—exhibiting MIC values of 0.25–2.50 μL/mL.

  1. EM International. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    It is the intent of EM International to describe the Office of Environmental Restoration and Waste Management`s (EM`s) various roles and responsibilities within the international community. Cooperative agreements and programs, descriptions of projects and technologies, and synopses of visits to international sites are all highlighted in this semiannual journal. Focus on EM programs in this issue is on international collaboration in vitrification projects. Technology highlights covers: in situ sealing for contaminated sites; and remote sensors for toxic pollutants. Section on profiles of countries includes: Arctic contamination by the former Soviet Union, and EM activities with Germany--cooperative arrangements.

  2. Microsatellite Loci in the Gypsophyte <em>Lepidium subulatum em>(Brassicaceae, and Transferability to Other <em>Lepidieae>

    Directory of Open Access Journals (Sweden)

    José Gabriel Segarra-Moragues

    2012-09-01

    Full Text Available Polymorphic microsatellite markers were developed for the Ibero-North African, strict gypsophyte <em>Lepidium subulatumem> to unravel the effects of habitat fragmentation in levels of genetic diversity, genetic structure and gene flow among its populations. Using 454 pyrosequencing 12 microsatellite loci including di- and tri-nucleotide repeats were characterized in <em>L. subulatumem>. They amplified a total of 80 alleles (2–12 alleles per locus in a sample of 35 individuals of <em>L. subulatumem>, showing relatively high levels of genetic diversity, <em>H>O = 0.645, <em>H>E = 0.627. Cross-species transferability of all 12 loci was successful for the Iberian endemics <em>Lepidium cardaminesem>, <em>Lepidium stylatumem>, and the widespread, <em>Lepidium graminifoliumem> and one species each of two related genera, <em>Cardaria drabaem> and <em>Coronopus didymusem>. These microsatellite primers will be useful to investigate genetic diversity, population structure and to address conservation genetics in species of <em>Lepidium>.

  3. New Trifluoromethyl Triazolopyrimidines as Anti-<em>Plasmodium> <em>falciparum> Agents

    Directory of Open Access Journals (Sweden)

    Núbia Boechat

    2012-07-01

    Full Text Available According to the World Health Organization, half of the World’s population, approximately 3.3 billion people, is at risk for developing malaria. Nearly 700,000 deaths each year are associated with the disease. Control of the disease in humans still relies on chemotherapy. Drug resistance is a limiting factor, and the search for new drugs is important. We have designed and synthesized new 2-(trifluoromethyl[1,2,4]triazolo[1,5-<em>a>]pyrimidine derivatives based on bioisosteric replacement of functional groups on the anti-malarial compounds mefloquine and amodiaquine. This approach enabled us to investigate the impact of: (i ring bioisosteric replacement; (ii a CF3 group substituted at the 2-position of the [1,2,4]triazolo[1,5-<em>a>]pyrimidine scaffold and (iii a range of amines as substituents at the 7-position of the of heterocyclic ring; on <em>in vitroem> activity against <em>Plasmodium falciparumem>. According to docking simulations, the synthesized compounds are able to interact with <em>P. falciparumem> dihydroorotate dehydrogenase (<em>Pf>DHODH through strong hydrogen bonds. The presence of a trifluoromethyl group at the 2-position of the [1,2,4]triazolo[1,5-<em>a>]pyrimidine ring led to increased drug activity. Thirteen compounds were found to be active, with IC50 values ranging from 0.023 to 20 µM in the anti-HRP2 and hypoxanthine assays. The selectivity index (SI of the most active derivatives 5, 8, 11 and 16 was found to vary from 1,003 to 18,478.

  4. Study protocol for the recreational stimulation for elders as a vehicle to resolve delirium superimposed on dementia (Reserve For DSD trial

    Directory of Open Access Journals (Sweden)

    Leslie Doug

    2011-05-01

    Full Text Available Abstract Background Delirium is a state of confusion characterized by an acute and fluctuating decline in cognitive functioning. Delirium is common and deadly in older adults with dementia, and is often referred to as delirium superimposed on dementia, or DSD. Interventions that treat DSD are not well-developed because the mechanisms involved in its etiology are not completely understood. We have developed a theory-based intervention for DSD that is derived from the literature on cognitive reserve and based on our prior interdisciplinary work on delirium, recreational activities, and cognitive stimulation in people with dementia. Our preliminary work indicate that use of simple, cognitively stimulating activities may help resolve delirium by helping to focus inattention, the primary neuropsychological deficit in delirium. Our primary aim in this trial is to test the efficacy of Recreational Stimulation for Elders as a Vehicle to resolve DSD (RESERVE- DSD. Methods/Design This randomized repeated measures clinical trial will involve participants being recruited and enrolled at the time of admission to post acute care. We will randomize 256 subjects to intervention (RESERVE-DSD or control (usual care. Intervention subjects will receive 30-minute sessions of tailored cognitively stimulating recreational activities for up to 30 days. We hypothesize that subjects who receive RESERVE-DSD will have: decreased severity and duration of delirium; greater gains in attention, orientation, memory, abstract thinking, and executive functioning; and greater gains in physical function compared to subjects with DSD who receive usual care. We will also evaluate potential moderators of intervention efficacy (lifetime of complex mental activities and APOE status. Our secondary aim is to describe the costs associated with RESERVE-DSD. Discussion Our theory-based intervention, which uses simple, inexpensive recreational activities for delivering cognitive stimulation

  5. Screening and Analysis of the Potential Bioactive Components in Rabbit Plasma after Oral Administration of Hot-Water Extracts from Leaves of <em>B>ambusa em>>textilis em>McClure

    Directory of Open Access Journals (Sweden)

    Jia Sun

    2012-07-01

    Full Text Available <em>Bambusa textilisem> McClure is a traditional Chinese medicinal plant belonging to the Bambusoideae subfamily and used to treat chronic fever and infectious diseases. To investigate the bioactive compounds absorbed in the rabbit blood after oral administration of hot-<em>water extractem>>s from em>>the leaves of em>>B. textilisem> McClure, a validated chromatographic fingerprint method was established using LC-Q-TOF-MS. Twenty compounds in bamboo leaves and three potential bioactive compounds in rabbit plasma were detected. Of the twenty detected compounds <em>in vitroem>, fifteen of which were tentatively identified either by comparing the retention time and mass spectrometry data with that of reference compounds or by reviewing the literature. Three potential bioactive compounds, including (<em>E-p>-coumaric acid, (<em>Z-p>-coumaric acid, and apigenin-8-<em>C>-β-D-(2"-<em>O>-α-L-rhamnosyl-gluco-pyranoside, were detected in both <em>the leaves of em>>B. textilis em>McClure and rabbit plasma. Of the three compounds, apigenin-8-<em>C>-β-D-(2"-<em>O>-α-L-rhamnosylglucopyranoside was identified based on its UV, MS, and NMR spectra. This study provides helpful chemical information for further pharmacology and active mechanism research on <em>B. textilisem> McClure.

  6. Genotoxicity of <em>Euphorbia hirtaem>: An <em>Allium cepaem> Assay

    Directory of Open Access Journals (Sweden)

    Kwan Yuet Ping

    2012-06-01

    Full Text Available The potential genotoxic effects of methanolic extracts of <em>Euphorbia hirta em>which is commonly used in traditional medicine to treat a variety of diseased conditions including asthma, coughs, diarrhea and dysentery was investigated using <em>Allium cepaem> assay. The extracts of 125, 250, 500 and 1,000 µg/mL were tested on root meristems of <em>A. cepaem>. Ethylmethanesulfonate was used as positive control and distilled water was used as negative control. The result showed that mitotic index decreased as the concentrations of <em>E. hirtaem> extract increased. A dose-dependent increase of chromosome aberrations was also observed. Abnormalities scored were stickiness, c-mitosis, bridges and vagrant chromosomes. Micronucleated cells were also observed at interphase. Result of this study confirmed that the methanol extracts of <em>E. hirta em>exerted significant genotoxic and mitodepressive effects at 1,000 µg/mL.

  7. <em>In Vitroem> Antioxidant Properties of Flavonoids and Polysaccharides Extract from Tobacco (<em>Nicotiana> em>tabacum> L. Leaves

    Directory of Open Access Journals (Sweden)

    Jing-Lu Wang

    2012-09-01

    Full Text Available In the present study, antioxidant properties of flavonoids and polysaccharides from tobacco (<em>Nicotiana> tabacumem> L. leaves were evaluated in several <em>in vitroem> systems, e.g., scavenging activities on hydroxyl, superoxide anion, 1,1-diphenyl-2-picrylhydrazyl (DPPH and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS radicals, and reducing power. Flavonoids showed much better activity than polysaccharides in scavenging activities on free radicals. When compared to the positive control, ascorbic acid, both showed weaker antioxidant potential. However, flavonoids possessed comparable superoxide anion, DPPH and ABTS radical scavenging abilities to ascorbic acid at high concentration (600 μg/mL. Meanwhile, it was found that flavonoids had prominent effects on the reducing power, which was equivalent to ascorbic acid, and was significantly higher than polysaccharides. These results clearly indicate that flavonoids are effective in scavenging free radicals and have the potential to be powerful antioxidants. Thus, tobacco leaves could be considered as a potential source of natural antioxidants for food, pharmaceutical, cosmetics or nutraceutical industries.

  8. Basic geological features of superimposed basin and hydrocarbon accumulation in Sichuan Basin, China%四川含油气叠合盆地基本特征

    Institute of Scientific and Technical Information of China (English)

    刘树根; 李智武; 孙玮; 邓宾; 罗志立; 王国芝; 雍自权; 黄文明

    2011-01-01

    The recent breakthroughs in natural gas exploration in Siehuan Basin have been making it urgent and indispensable to reinvestigate its basic geological features and characteristics of hydrocarbon accumulation. Being a typical superimposed basin, Sichuan Basin has experienced three major phases of basin evolution during the Phanerozoic time as follows:marine carbonate platform with differential subsidence-uplift in extensional setting from Sinian to Middle Triassic,continental clastic basin with fold-and-thrust deformation under compressive background from Late Triassic to Eocene,and uplift and structural modification since Oligocene. Simultaneously,Sichuan Basin has also gone through three key periods of tectonic transformation. The first tectonic transformation in Late Triassic time is characterized by the changes of tectonic settings from extension to compression, basin property from passive continental margin to foreland basin,deposition from marine carbonate to marine clastic and to continental clastic. The second tectonic transformation in early Late Cretaceous is symbolized by the migration of foredeep,tectonic domain change from Qinling orogenic belt to Tibet Plateau, and the change from deposition to partial uplift and erosion. The last tectonic transformation in Eocene is represented by the changes from exorheic basin to endorheic basin, from sedimentary basin to topographic basin, and from deposition to overall uplift and erosion. Affected jointly by peripheral structural belts since Indosinian movement (the Qinling orogenic belt on the north side, Xuefeng intracontinental tectonic system on the east and southeast sides,and Tibet Plateau on the west and southwest sides), multi-stage and multi-direction structures were superimposed in Sichuan Basin. The present-day basin-orogen configuration in Sichuan Basin and adjacent regions exhibits clear trisection in topography, basement and surface structural features, and two types of basin-orogen boundaries, i. e

  9. Emergency Medical Service (EMS) Stations

    Data.gov (United States)

    Kansas Data Access and Support Center — EMS Locations in Kansas The EMS stations dataset consists of any location where emergency medical services (EMS) personnel are stationed or based out of, or where...

  10. Isolation and Characterization of a Lycopene ε-Cyclase Gene of <em>Chlorella em>(Chromochloris> <em>zofingiensis>. Regulation of the Carotenogenic Pathway by Nitrogen and Light

    Directory of Open Access Journals (Sweden)

    Maria Angeles Vargas

    2012-09-01

    Full Text Available The isolation and characterization of the lycopene ε-cyclase gene from the green microalga <em>Chlorella em>(Chromochloris> <em>zofingiensis> (<em>Czlcy-e> was performed. This gene is involved in the formation of the carotenoids α-carotene and lutein. <em>Czlcy-e> gene encoded a polypeptide of 654 amino acids. A single copy of <em>Czlcy-e> was found in <em>C. zofingiensisem>. Functional analysis by heterologous complementation in <em>Escherichia coliem> showed the ability of this protein to convert lycopene to δ-carotene. In addition, the regulation of the carotenogenic pathway by light and nitrogen was also studied in <em>C. zofingiensisem>. High irradiance stress did not increase mRNA levels of neither lycopene β<em>->cyclase gene (<em>lcy-b> nor lycopene ε-cyclase gene<em> em>(lcy-e> as compared with low irradiance conditions, whereas the transcript levels of <em>psy>, <em>pds>, <em>chyB> and <em>bkt> genes were enhanced, nevertheless triggering the synthesis of the secondary carotenoids astaxanthin, canthaxanthin and zeaxanthin and decreasing the levels of the primary carotenoids α-carotene, lutein, violaxanthin and β-carotene. Nitrogen starvation <em>per seem> enhanced mRNA levels of all genes considered, except <em>lcy-e and pdsem>, but did not trigger the synthesis of astaxanthin, canthaxanthin nor zeaxanthin. The combined effect of both high light and nitrogen starvation stresses enhanced significantly the accumulation of these carotenoids as well as the transcript levels of <em>bkt> gene, as compared with the effect of only high irradiance stress.

  11. <em>Angiostrongylus vasorumem> in red foxes (<em>Vulpes vulpesem> and badgers (<em>Meles melesem> from Central and Northern Italy

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    Marta Magi

    2010-06-01

    Full Text Available Abstract During 2004-2005 and 2007-2008, 189 foxes (<em>Vulpes vulpesem> and 6 badgers (<em>Meles melesem> were collected in different areas of Central Northern Italy (Piedmont, Liguria and Tuscany and examined for <em>Angiostrongylus vasorumem> infection. The prevalence of the infection was significantly different in the areas considered, with the highest values in the district of Imperia (80%, Liguria and in Montezemolo (70%, southern Piedmont; the prevalence in Tuscany was 7%. One badger collected in the area of Imperia turned out to be infected, representing the first report of the parasite in this species in Italy. Further studies are needed to evaluate the role played by fox populations as reservoirs of infection and the probability of its spreading to domestic dogs.
    Riassunto <em>Angiostrongylus vasorumem> nella volpe (<em>Vulpes vulpesem> e nel tasso (<em>Meles melesem> in Italia centro-settentrionale. Nel 2004-2005 e 2007-2008, 189 volpi (<em>Vulpes vulpesem> e 6 tassi (<em>Meles melesem> provenienti da differenti aree dell'Italia settentrionale e centrale (Piemonte, Liguria Toscana, sono stati esaminati per la ricerca di <em>Angiostrongylus vasorumem>. La prevalenza del nematode è risultata significativamente diversa nelle varie zone, con valori elevati nelle zone di Imperia (80% e di Montezemolo (70%, provincia di Cuneo; la prevalenza in Toscana è risultata del 7%. Un tasso proveniente dall'area di Imperia è risultato positivo per A. vasorum; questa è la prima segnalazione del parassita in tale specie in Italia. Ulteriori studi sono necessari per valutare il potenziale della volpe come serbatoio e la possibilità di diffusione della parassitosi ai cani domestici.

    doi:10.4404/hystrix-20.2-4442

  12. <em>An entem>-Kaurane-Type Diterpene in <em>Croton antisyphiliticusem> Mart.

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    Ana Maria Pereira

    2012-07-01

    Full Text Available <em>Croton antisyphiliticus em>is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract. Crude extract, fractions and pure compound isolated from roots of this species were investigated to validate their antimicrobial activity against <em>Escherichia coliem> and <em>Staphylococcus aureusem>. The compound <em>ent>-kaur-16-en-18-oic acid was isolated as a major component (0.7% of crude extract, and its MIC value determined against <em>S. aureusem> (ATCC 6538 was 250 μg/mL. This is the first phytochemical work on the species monitored with antimicrobial assay.

  13. Expression of Selected <em>Ginkgo em>>biloba em>Heat Shock Protein Genes After Cold Treatment Could Be Induced by Other Abiotic Stress

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    Feng Xu

    2012-05-01

    Full Text Available Heat shock proteins (HSPs play various stress-protective roles in plants. In this study, three <em>HSP> genes were isolated from a suppression subtractive hybridization (SSH cDNA library of <em>Ginkgo bilobaem> leaves treated with cold stress. Based on the molecular weight, the three genes were designated <em>GbHSP16.8em>, <em>GbHSP17em> and <em>GbHSP70em>. The full length of the three genes were predicted to encode three polypeptide chains containing 149 amino acids (Aa, 152 Aa, and 657 Aa, and their corresponding molecular weights were predicted as follows: 16.67 kDa, 17.39 kDa, and 71.81 kDa respectively. The three genes exhibited distinctive expression patterns in different organs or development stages. <em>GbHSP16.8em> and <em>GbHSP70em> showed high expression levels in leaves and a low level in gynoecia, <em>GbHSP17em> showed a higher transcription in stamens and lower level in fruit. This result indicates that <em>GbHSP16.8em> and <em>GbHSP70 em>may play important roles in <em>Ginkgo> leaf development and photosynthesis, and <em>GbHSP17em> may play a positive role in pollen maturation. All three <em>GbHSPs> were up-regulated under cold stress, whereas extreme heat stress only caused up-regulation of <em>GbHSP70em>, UV-B treatment resulted in up-regulation of <em>GbHSP16.8em> and <em>GbHSP17em>, wounding treatment resulted in up-regulation of <em>GbHSP16.8em> and <em>GbHSP70em>, and abscisic acid (ABA treatment caused up-regulation of <em>GbHSP70em> primarily.

  14. Pesquisando em fontes visuais

    OpenAIRE

    Proença, Caio Carvalho; FFCH

    2012-01-01

    O presente ensaio pretende demonstrar reflexões sobre os usos da fotografia como fonte. Na primeira parte do ensaio procura-se demonstrar a experiência de um primeiro contato com a fonte visual, em especial a fotografia, para posteriormente entrar em contato com as diferentes formas metodológicas presente na pesquisa desta fonte. Em um segundo momento mostra-se alguns apontamentos sobre o método de pesquisa voltado à fonte visual fotográfica que auxiliam a pesquisa, contemplando a discussão s...

  15. Meteorologia em linha

    OpenAIRE

    2015-01-01

    DISPOSITIVO TÉCNICO-PEDAGÓGICO: CURSO DE METEOROLOGIA EM LINHA. Designamos por curso o sistema que resulta da relação entre um conjunto de componentes, dando unidade e identidade ao mesmo, incorporados na plataforma Versal: conjunto de 30 lições em vídeo, recursos complementares, valorização e contextualização do curso, orientação e acompanhamento desenhados e previstos, interação com os utilizadores do curso a partir do momento da sua edição aberta em linha. (https://versal.com/c/1fzwaz/m...

  16. A hipnose em triatletas

    OpenAIRE

    Szenészi, Daniela Scharamm

    2005-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Psicologia. Esta pesquisa objetivou investigar em atletas de triatlon a percepção das características da visualização da prova de Ironman e os seus componentes psicofisiológicos durante o transe hipnótico. Foram estudados 7 atletas do sexo masculino em 6 sessões de hipnose. Após cada sessão foi feita uma entrevista semi-estruturada e aplicado um questionário...

  17. Osteoartrites em equinos

    OpenAIRE

    Rocha, Francisco José Martins

    2008-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária A Osteoartrite (OA) é a principal causa de claudicação no cavalo de desporto e lazer, sendo uma afecção que tem grandes repercussões económicas. Este trabalho descreve algumas das características importantes da estrutura articular, bem como da sua fisiologia. Define a OA e todas as estruturas envolvidas no seu processo. Os mecanismos fisiopatológicos põem em evidência os factores de risco em causa e que determinam tod...

  18. Literatura em quadrinhos

    OpenAIRE

    Ferreira,Tânia Regina

    2015-01-01

    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Literatura, Florianópolis, 2015. O objetivo desta tese é fazer o estudo do desfecho do romance de Lima Barreto, Triste fim de Policarpo Quaresma - (centenário de publicação em livro 1915-2015) - adaptado para as quatro versões homônimas em quadrinhos por: Edgar Vasques e Flávio Braga (Desiderata, 2010); Cesar Lobo e Luiz Antonio Aguiar (Ática, 2010); Lailson de Holanda...

  19. Melhores medicamentos em Pediatria

    OpenAIRE

    2014-01-01

    Resumo: Existem actualmente muitos medicamentos que são utilizados em crianças sem terem sido suficientemente estudados nas diferentes sub-populações pediátricas, com consequências preocupantes. O reconhecimento deste facto levou à criação de regras específicas na investigação de medicamentos pediátricos nos EUA, já em 1997. De igual forma, o Regulamento de Medicamentos para Uso Pediátrico aprovado em De zembro de 2006 pelo Parlamento Europeu, tem como objectivo a resolução deste problema no ...

  20. Characterization of <em>Erysiphe necatorem>-Responsive Genes in Chinese Wild <em>Vitis> <em>quinquangularis>

    Directory of Open Access Journals (Sweden)

    Xiping Wang

    2012-09-01

    Full Text Available Powdery mildew (PM, caused by fungus <em>Erysiphe necatorem>, is one of the most devastating diseases of grapevine. To better understand grapevine-PM interaction and provide candidate resources for grapevine breeding, a suppression subtractive hybridization (SSH cDNA library was constructed from <em>E. necatorem>-infected leaves of a resistant Chinese wild <em>Vitis quinquangularisem> clone “Shang-24”. A total of 492 high quality expressed sequence tags (ESTs were obtained and assembled into 266 unigenes. Gene ontology (GO analysis indicated that 188 unigenes could be assigned with at least one GO term in the biological process category, and 176 in the molecular function category. Sequence analysis showed that a large number of these genes were homologous to those involved in defense responses. Genes involved in metabolism, photosynthesis, transport and signal transduction were also enriched in the library. Expression analysis of 13 selected genes by qRT-PCR revealed that most were induced more quickly and intensely in the resistant material “Shang-24” than in the sensitive <em>V. pseudoreticulata em>clone “Hunan-1” by<em> E. necatorem> infection. The ESTs reported here provide new clues to understand the disease-resistance mechanism in Chinese wild grapevine species and may enable us to investigate <em>E. necatorem>-responsive genes involved in PM resistance in grapevine germplasm.

  1. Synthesis, Reactions and Evaluation of the Antimicrobial Activity of Some 4-(<em>p>-Halophenyl-4<em>H>-naphthopyran, Pyranopyrimidine and Pyranotriazolopyrimidine Derivatives

    Directory of Open Access Journals (Sweden)

    Ashraf H. F. Abd El-Wahab

    2012-07-01

    Full Text Available A series of naphthopyran derivatives 3a–f were prepared. Reaction of <em>2-em>amino-4-(<em>p>-chlorophenyl-7-methoxy-4<em>H>-naphtho[2,1-<em>b>]pyran-3-carbonitrile (3b with Ac2O afforded two products, 2-acetylamino-7-methoxy-4-(<em>p>-chlorophenyl-4<em>H>-naphtho-[2,1-<em>b>]pyran-3-carbonitrile (4 and 10,11-dihydro-3-methoxy-9-methyl-12-(<em>p>-chloro-phenyl-12<em>H>-naphtho[2,1-<em>b>]pyran[2,3-<em>d>]pyrimidine-11-one (5 and treatment of 3b with benzoyl chloride gave the pyranopyrimidin-11-one derivative 6. While treatment of 3b with formamide afforded 11-amino-3-methoxy-12-(<em>p>-chlorophenyl-12<em>H>-naphtho[2,1-<em>b>]pyrano[2,3-<em>d>]pyrimidine (7. Reaction of 3b with triethyl orthoformate gave the corresponding 2-ethoxymethyleneamino-7-methoxy-4-(<em>p>-chlorophenyl-4<em>H>-naphtho-[2,1-<em>b>]pyran-3-carbonitrile (8. Hydrazinolysis of 8 in EtOH at room temperature yielded 10-amino-10,11-dihydro-11-imino-3-methoxy-12-(<em>p>-chlorophenyl-12<em>H>-naphtho[2,1-b]pyrano-[2,3-d]pyrimidine (9, while aminolysis of 8 with methylamine or dimethylamine gave the corresponding pyranopyrimidine and <em>N,N>-dimethylaminomethylene derivatives 10 and 11. Condensation of 9 with some carboxylic acid derivatives afforded triazolopyrimidine derivatives 12–16, while reaction of 9 with benzaldehyde gave 10-benzalamino-10,11-dihydro-11-imino-3-methoxy-12-(<em>p>-chlorophenyl12<em>H>-naphtho[2,1-<em>b>]pyrano[2,3-<em>d>]pyrimidine (17. The structures of the newly synthesized compounds were confirmed by spectral data. The

  2. International EMS Systems

    DEFF Research Database (Denmark)

    Langhelle, Audun; Lossius, Hans Morten; Silfvast, Tom;

    2004-01-01

    Emergency medicine service (EMS) systems in the five Nordic countries have more similarities than differences. One similarity is the involvement of anaesthesiologists as pre-hospital physicians and their strong participation for all critically ill and injured patients in-hospital. Discrepancies do...... exist, however, especially within the ground and air ambulance service, and the EMS systems face several challenges. Main problems and challenges emphasized by the authors are: (1) Denmark: the dispatch centres are presently not under medical control and are without a national criteria based system....... Access to on-line medical advice of a physician is not available; (2) Finland: the autonomy of the individual municipalities and their responsibility to cover for primary and specialised health care, as well as the EMS, and the lack of supporting or demanding legislation regarding the EMS; (3) Iceland...

  3. Preconceito em disfarce

    Directory of Open Access Journals (Sweden)

    João de Almeida

    2001-02-01

    Full Text Available

    0 presente estudo pretende analisar os significados básicos do texto "Preto e Branco", de F. Sabino, valendo-se de alguns modelos teóricos lingüísticos, principalmente de Greimas e de Pottier, em seqüência que vai da estrutura da narrativa e do percurso gerativo de sentido até as relações sêmicas, em especial.

  4. <em>In Vitro em>and <em>in em>Vivo> Antitumor Effect of Trachylobane-360, a Diterpene from<em> Xylopia langsdorffianaem>

    Directory of Open Access Journals (Sweden)

    João Carlos Lima Rodrigues Pita

    2012-08-01

    Full Text Available Trachylobane-360 (<em>ent>-7α-acetoxytrachyloban-18-oic acid was isolated from <em>Xylopia langsdorffianaem>. Studies have shown that it has weak cytotoxic activity against tumor and non-tumor cells. This study investigated the <em>in vitroem>> em>and <em>in vivoem> antitumor effects of trachylobane-360, as well as its cytotoxicity in mouse erythrocytes. In order to evaluate the <em>in vivoem> toxicological aspects related to trachylobane-360 administration, hematological, biochemical and histopathological analyses of the treated animals were performed. The compound exhibited a concentration-dependent effect in inducing hemolysis with HC50 of 273.6 µM, and a moderate <em>in vitroem>> em>concentration-dependent inhibitory effect on the proliferation of sarcoma 180 cells with IC50 values of 150.8 µM and 150.4 µM, evaluated by the trypan blue exclusion test and MTT reduction assay, respectively. The <em>in vivoem> inhibition rates of sarcoma 180 tumor development were 45.60, 71.99 and 80.06% at doses of 12.5 and 25 mg/kg of trachylobane-360 and 25 mg/kg of 5-FU, respectively. Biochemical parameters were not altered. Leukopenia was observed after 5-FU treatment, but this effect was not seen with trachylobane-360 treatment. The histopathological analysis of liver and kidney showed that both organs were mildly affected by trachylobane-360 treatment. Trachylobane-360 showed no immunosuppressive effect. In conclusion, these data reinforce the anticancer potential of this natural diterpene.

  5. Purification, Characterization and Antioxidant Activities <em>in Vitroem>> em>and <em>in Vivoem> of the Polysaccharides from <em>Boletus edulisem> Bull

    Directory of Open Access Journals (Sweden)

    Yijun Fan

    2012-07-01

    Full Text Available A water-soluble polysaccharide (BEBP was extracted from <em>Boletus edulis em>Bull using hot water extraction followed by ethanol precipitation. The polysaccharide BEBP was further purified by chromatography on a DEAE-cellulose column, giving three major polysaccharide fractions termed BEBP-1, BEBP-2 and BEBP-3. In the next experiment, the average molecular weight (Mw, IR and monosaccharide compositional analysis of the three polysaccharide fractions were determined. The evaluation of antioxidant activities both <em>in vitroem> and <em>in vivo em>suggested that BEBP-3 had good potential antioxidant activity, and should be explored as a novel potential antioxidant.

  6. Sulla presenza di <em>Sorex antinoriiem>, <em>Neomys anomalusem> (Insectivora, Soricidae e <em>Talpa caecaem> (Insectivora, Talpidae in Umbria

    Directory of Open Access Journals (Sweden)

    A.M. Paci

    2003-10-01

    Full Text Available Lo scopo del contributo è di fornire un aggiornamento sulla presenza del Toporagno del Vallese <em>Sorex antinoriiem>, del Toporagno acquatico di Miller <em>Neomys anomalusem> e della Talpa cieca <em>Talpa caecaem> in Umbria, dove le specie risultano accertate ormai da qualche anno. A tal fine sono stati rivisitati i reperti collezionati e la bibliografia conosciuta. Toporagno del Vallese: elevato di recente a livello di specie da Brünner et al. (2002, altrimenti considerato sottospecie del Toporagno comune (<em>S. araneus antinoriiem>. È conservato uno di tre crani incompleti (mancano mandibole ed incisivi superiori al momento prudenzialmente riferiti a <em>Sorex> cfr. <em>antinorii>, provenienti dall?Appennino umbro-marchigiano settentrionale (dintorni di Scalocchio - PG, 590 m. s.l.m. e determinati sulla base della pigmentazione rossa degli ipoconi del M1 e M2; Toporagno acquatico di Miller: tre crani (Breda in Paci e Romano op. cit. e un esemplare intero (Paci, ined. sono stati trovati a pochi chilometri di distanza gli uni dall?altro tra i comuni di Assisi e Valfabbrica, in ambienti mediocollinari limitrofi al Parco Regionale del M.te Subasio (Perugia. In provincia di Terni la specie viene segnalata da Isotti (op. cit. per i dintorni di Orvieto. Talpa cieca: sono noti una femmina e un maschio raccolti nel comune di Pietralunga (PG, rispettivamente in una conifereta a <em>Pinus nigraem> (m. 630 s.l.m. e nelle vicinanze di un bosco misto collinare a prevalenza di <em>Quercus cerrisem> (m. 640 s.l.m.. Recentemente un terzo individuo è stato rinvenuto nel comune di Sigillo (PG, all?interno del Parco Regionale di M.te Cucco, sul margine di una faggeta a 1100 m s.l.m. In entrambi i casi l?areale della specie è risultato parapatrico con quello di <em>Talpa europaeaem>.

  7. Glycosylation of Vanillin and 8-Nordihydrocapsaicin by Cultured <em>Eucalyptus perrinianaem> Cells

    Directory of Open Access Journals (Sweden)

    Naoji Kubota

    2012-05-01

    Full Text Available Glycosylation of vanilloids such as vanillin and 8-nordihydrocapsaicin by cultured plant cells of <em>Eucalyptus perrinianaem> was studied. Vanillin was converted into vanillin 4-<em>O>-b-D-glucopyranoside, vanillyl alcohol, and 4-<em>O>-b-D-glucopyranosylvanillyl alcohol by <em>E. perriniana em>cells. Incubation of cultured <em>E. perrinianaem> cells with 8-nor- dihydrocapsaicin gave 8-nordihydrocapsaicin 4-<em>O>-b-D-glucopyranoside and 8-nordihydro- capsaicin 4-<em>O>-b-D-gentiobioside.

  8. A specimen of <em>Sorex> cfr. <em>samniticus> in Barn Owl's pellets from Murge plateau (Apulia, Italy / Su di un <em>Sorex> cfr. <em>samniticus> (Insectivora, Soricidae rinvenuto in borre di <em>Tyto albaem> delle Murge (Puglia, Italia

    Directory of Open Access Journals (Sweden)

    Giovanni Ferrara

    1992-07-01

    Full Text Available Abstract In a lot of Barn Owl's pellets from the Murge plateau a specimen of <em>Sorex> sp. was detected. Thank to some morphological and morphometrical features, the cranial bones can be tentatively attributed to <em>Sorex samniticusem> Altobello, 1926. The genus <em>Sorex> was not yet included in the Apulia's fauna southwards of the Gargano district; the origin and significance of the above record is briefly discussed, the actual presence of a natural population of <em>Sorex> in the Murge being not yet proved. Riassunto Viene segnalato il rinvenimento di un esemplare di <em>Sorex> cfr. <em>samniticus> da borre di <em>Tyto albaem> delle Murge. Poiché il genere non era stato ancora segnalato nella Puglia a sud del Gargano, viene discusso il significato faunistico del reperto.

  9. Study of the <em>in Vitroem> Antiplasmodial, Antileishmanial and Antitrypanosomal Activities of Medicinal Plants from Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Nawal M. Al-Musayeib

    2012-09-01

    Full Text Available The present study investigated the <em>in vitroem> antiprotozoal activity of sixteen selected medicinal plants. Plant materials were extracted with methanol and screened <em>in vitroem> against erythrocytic schizonts of <em>Plasmodium falciparumem>, intracellular amastigotes of <em>Leishmania infantum em>and <em>Trypanosoma cruzi em>and free trypomastigotes of<em> T. bruceiem>. Cytotoxic activity was determined against MRC-5 cells to assess selectivity<em>. em>The criterion for activity was an IC50 < 10 µg/mL (4. Antiplasmodial activity was found in the<em> em>extracts of<em> em>>Prosopis julifloraem> and <em>Punica granatumem>. Antileishmanial activity<em> em>against <em>L. infantumem> was demonstrated in <em>Caralluma sinaicaem> and <em>Periploca aphylla.em> Amastigotes of<em> T. cruzi em>were affected by the methanol extract of<em> em>>Albizia lebbeckem>> em>pericarp, <em>Caralluma sinaicaem>,> Periploca aphylla em>and <em>Prosopius julifloraem>. Activity against<em> T. brucei em>was obtained in<em> em>>Prosopis julifloraem>. Cytotoxicity (MRC-5 IC50 < 10 µg/mL and hence non-specific activities were observed for<em> em>>Conocarpus lancifoliusem>.>

  10. EMS in Mauritius.

    Science.gov (United States)

    Ramalanjaona, Georges; Brogan, Gerald X

    2009-02-01

    Mauritius lies in the southwest Indian Ocean about 1250 miles from the African coast and 500 miles from Madagascar. Mauritius (estimated population 1,230,602) became independent from the United Kingdom in 1968 and has one of the highest GDP per capita in Africa. Within Mauritius there is a well established EMS system with a single 999 national dispatch system. Ambulances are either publicly or privately owned. Public ambulances are run by the Government (SAMU). Megacare is a private subscriber only ambulance service. The Government has recently invested in new technology such as telemedicine to further enhance the role of EMS on the island. This article describes the current state of EMS in Mauritius and depicts its development in the context of Government effort to decentralise and modernise the healthcare system.

  11. Acidose ruminal em caprinos

    OpenAIRE

    Cunha, José Diogo de Oliveira e silva Ribeiro da

    2012-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária Com este trabalho pretendeu-se fazer uma revisão acerca da acidose ruminal em caprinos, visto haver pouca bibliografia sobre o tema. Este trabalho foi baseado na revisão bibliográfica de artigos científicos e completado através da observação de casos clínicos ocorridos durante o estágio curricular. O objectivo deste estudo foi realizar uma breve revisão da anatomia e fisiologia do tracto gastrointestinal dos caprinos assim com...

  12. Ulisses em Kafka

    Directory of Open Access Journals (Sweden)

    Stéphane Mosès

    2015-02-01

    Full Text Available ResumoEm sua introdução para Exegese de uma lenda, Stéphane Mosès afirma que a obra de Kafka não necessita de novas interpretações, mas sim de uma “análise rigorosa de sua lógica subjacente”. Assim, em “Ulisses em Kafka”, investigandoa dialética formal de “O silêncio das sereias”, Mosès procura expor a estrutura narrativa que comandaria esse breve texto em que o escritor tcheco acrescenta à astucia de Ulisses a ingenuidade como elemento de salvação.Palavras-chave: Kafka; dialética; salvação.AbstractIn his introduction to Exegèse d’une légende, Stéphane Mosès affirms that Kafka’s works are not in need of new interpretations, but rather, of a “rigorous analysis of their underlying logic”. Thus, in “Ulisses chez Kafka”, by investigating the formal dialectic of “Das Schweigen der Sirenen”, Mosès seeks to exhibit the narrative structure that would supposedly guide this short text in which the Czech author adds naïveté to Ulisses’s cunning intelligence as an element of salvation.Keywords: Kafka; dialectic; salvation.Stéphane Mosès foi professor emérito da Universidade Hebraica de Jerusalém, onde ensinou Literatura Alemã e Comparada, entre os seus principais interesses estavam o pensamento de Franz Rosenzweig e de Walter Benjamin e as literaturas de Franz Kafka e de Paul Célan. Autor de diversos livros, entre eles: L'ange de l'histoire. Rosenzweig, Benjamin, Scholem, Exégèse d'une légende, lectures de Kafka, e Rêves de Freud. Six lectures.Rodrigo Ielpo é doutor em literatura francesa pela UFRJ e em História e Semiologia do texto e da imagem pela Université Paris VII, com pós-doutorado em Teoria Literária pela UNICAMP. Professor Adjunto do Departamento de Letras Neolatinas da Universidade Federal do Rio de Janeiro, possui publicações e traduções nos seguintes temas: teoria e literatura francesa contemporâneas, escrita e processos de subjetivação.rodrigoielpo@gmail.com 

  13. International EMS Systems

    DEFF Research Database (Denmark)

    Langhelle, Audun; Lossius, Hans Morten; Silfvast, Tom

    2004-01-01

    exist, however, especially within the ground and air ambulance service, and the EMS systems face several challenges. Main problems and challenges emphasized by the authors are: (1) Denmark: the dispatch centres are presently not under medical control and are without a national criteria based system......Emergency medicine service (EMS) systems in the five Nordic countries have more similarities than differences. One similarity is the involvement of anaesthesiologists as pre-hospital physicians and their strong participation for all critically ill and injured patients in-hospital. Discrepancies do...

  14. Frenectomia em foco

    OpenAIRE

    Vieira, Joana Isabel Monteiro de Paiva

    2012-01-01

    Projeto de Pós Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária O freio é uma estrutura anatómica oral classificada em freio labial (médio maxilar ou mandibular, lateral maxilar ou mandibular) ou lingual que se pode tornar num problema quando a sua inserção cria impedimentos estruturais e dificuldades a vários níveis. Um freio labial anormal pode causar algumas anomalias ou problemas, tais como u...

  15. Cyberbullying em adolescentes brasileiros

    OpenAIRE

    Wendt, Guilherme Welter

    2012-01-01

    O cyberbullying é entendido como uma forma de comportamento agressivo que ocorre através dos meios eletrônicos de interação (computadores, celulares, sites de relacionamento virtual), sendo realizado de maneira intencional por uma pessoa ou grupo contra alguém em situação desigual de poder e, ainda, com dificuldade em se defender. Os estudos disponíveis até o presente momento destacam que o cyberbullying é um fator de risco para o desenvolvimento de sintomas de ansiedade, depressão, ideação s...

  16. Corantes vitais em cromovitrectomia

    OpenAIRE

    Dib, Eduardo; Rodrigues,Eduardo Büchelle; Maia, Maurício [UNIFESP; Meyer, Carsten H; Penha, Fernando Marcondes [UNIFESP; Furlani, Bruno de Albuquerque [UNIFESP; Costa, Elaine de Paula Fiod [UNIFESP; Farah, Michel Eid

    2009-01-01

    O objetivo do artigo é apresentar os dados atuais da aplicação de corantes vitais durante cirurgia vitreorretiniana, "cromovitrectomia", bem como uma revisão da literatura atual sobre o assunto no tocante às técnicas de aplicação, indicações e complicações em cromovitrectomia. Um grande número de publicações tem abordado o perfil tóxico da indocianina verde na cromovitrectomia. Dados experimentais mostram uma toxicidade dose-dependente da mesma em várias populações de células retinianas. Nova...

  17. O recasamento em Portugal

    OpenAIRE

    Lobo, Cristina; Conceição, Cristina Palma

    2003-01-01

    Identificar tendências do fenómeno do recasamento em Portugal, nas duas últimas décadas, constitui o objectivo principal deste artigo. Para essa identificação contribuiu o conhecimento da amplitude do próprio fenómeno, isto é, a percentagem de recasamentos no total dos casamentos em Portugal, e ainda um conjunto de variáveis que permitiu conhecer a caracterização social dos protagonistas do recasamento, por um lado, e delinear a diversidade dos seus trajectos conjugais após um divórcio, por o...

  18. Frenectomia em foco

    OpenAIRE

    Vieira, Joana Isabel Monteiro de Paiva

    2012-01-01

    Projeto de Pós Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária O freio é uma estrutura anatómica oral classificada em freio labial (médio maxilar ou mandibular, lateral maxilar ou mandibular) ou lingual que se pode tornar num problema quando a sua inserção cria impedimentos estruturais e dificuldades a vários níveis. Um freio labial anormal pode causar algumas anomalias ou problemas, tais como u...

  19. Acidose ruminal em caprinos

    OpenAIRE

    Cunha, José Diogo de Oliveira e silva Ribeiro da

    2012-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária Com este trabalho pretendeu-se fazer uma revisão acerca da acidose ruminal em caprinos, visto haver pouca bibliografia sobre o tema. Este trabalho foi baseado na revisão bibliográfica de artigos científicos e completado através da observação de casos clínicos ocorridos durante o estágio curricular. O objectivo deste estudo foi realizar uma breve revisão da anatomia e fisiologia do tracto gastrointestinal dos caprinos assim com...

  20. Horizontal Transmission of the Entomopathogen Fungus <em>Metarhizium anisopliae em>in <em>Microcerotermes diversusem> Groups

    Directory of Open Access Journals (Sweden)

    Mohammad Saied Mossadegh

    2012-08-01

    Full Text Available An experiment was carried out in order to investigate fungal conidia transmission of <em>Metarhizium anisopliae em>(Metschnikoff> em>Sorokin from vector (donor to healthy <em>Microcerotermes diversusem> Silvestri (Iso.: Termitidae and determine the best donor/concentration ratio for transmission. After preliminary trials, concentrations of 3.1 × 104, 3.9 × 105, 3.2 × 106 and 3.5 × 108 conidia mL−1 were selected for testing. The experiment was performed at three donor : Recipient ratios of 10, 30 and 50%. The highest mortality of recipient workers was observed after 14 days at the concentration of 3.5 × 108 conidia mL−1 and donor ratio of 50%. The mortality of recipient workers was less than 20% at all concentrations at a donor ratio of 10%. Our observations indicate social behavior of <em>M. diversusem>, such as grooming, can be effective in promoting epizootic outbreaks in a colony. While the current results suggest good potential for efficacy, the use of <em>M. anisopliaeem> as a component of integrated pest management of <em>M. diversusem> still needs to be proven under field conditions.

  1. Clinical Relevance of <em>CDH1em> and <em>CDH13em> DNA-Methylation in Serum of Cervical Cancer Patients

    Directory of Open Access Journals (Sweden)

    Günther K. Bonn

    2012-07-01

    Full Text Available This study was designed to investigate the DNA-methylation status of <em>E>-cadherin (<em>CDH1em> and <em>H>-cadherin (<em>CDH13em> in serum samples of cervical cancer patients and control patients with no malignant diseases and to evaluate the clinical utility of these markers. DNA-methylation status of <em>CDH1em> and <em>CDH13em> was analyzed by means of MethyLight-technology in serum samples from 49 cervical cancer patients and 40 patients with diseases other than cancer. To compare this methylation analysis with another technique, we analyzed the samples with a denaturing high performance liquid chromatography (DHPLC PCR-method. The specificity and sensitivity of <em>CDH1em> DNA-methylation measured by MethyLight was 75% and 55%, and for <em>CDH13em> DNA-methylation 95% and 10%. We identified a specificity of 92.5% and a sensitivity of only 27% for the <em>CDH1em> DHPLC-PCR analysis. Multivariate analysis showed that serum <em>CDH1em> methylation-positive patients had a 7.8-fold risk for death (95% CI: 2.2–27.7; <em>p> = 0.001 and a 92.8-fold risk for relapse (95% CI: 3.9–2207.1; <em>p> = 0.005. We concluded that the serological detection of <em>CDH1em> and <em>CDH13em> DNA-hypermethylation is not an ideal diagnostic tool due to low diagnostic specificity and sensitivity. However, it was validated that <em>CDH1em> methylation analysis in serum samples may be of potential use as a prognostic marker for cervical cancer patients.

  2. Time-Dependent Damage Investigation of Rock Mass in an <em>In> em>Situ> Experimental Tunnel

    Directory of Open Access Journals (Sweden)

    Jing Chen

    2012-08-01

    Full Text Available In underground tunnels or caverns, time-dependent deformation or failure of rock mass, such as extending cracks, gradual rock falls, <em>etc>., are a costly irritant and a major safety concern if the time-dependent damage of surrounding rock is serious. To understand the damage evolution of rock mass in underground engineering, an <em>in situem> experimental testing was carried out in a large belowground tunnel with a scale of 28.5 m in width, 21 m in height and 352 m in length. The time-dependent damage of rock mass was detected in succession by an ultrasonic wave test after excavation. The testing results showed that the time-dependent damage of rock mass could last a long time, <em>i.e.>, nearly 30 days. Regression analysis of damage factors defined by wave velocity, resulted in the time-dependent evolutional damage equation of rock mass, which corresponded with logarithmic format. A damage viscoelastic-plastic model was developed to describe the exposed time-dependent deterioration of rock mass by field test, such as convergence of time-dependent damage, deterioration of elastic modules and logarithmic format of damage factor. Furthermore, the remedial measures for damaged surrounding rock were discussed based on the measured results and the conception of damage compensation, which provides new clues for underground engineering design.

  3. Ultrasound-Assisted Extraction of Syringin from the Bark of <em>Ilex em>rotunda> Thumb Using Response Surface Methodology

    Directory of Open Access Journals (Sweden)

    Hui Wang

    2012-06-01

    Full Text Available In this work, a rapid extraction method based on ultrasound-assisted extraction (UAE of syringin from the bark of <em>Ilex rotunda em>Thumb using response surface methodology (RSM is described. The syringin was analyzed and quantified by high performance liquid chromatography coupled with UV detection (HPLC-UV. The extraction solvent, extraction temperature and extraction time, the three main factors for UAE, were optimized with Box-Behnken design (BBD to obtain the highest extraction efficiency. The optimal conditions were the use of a sonication frequency of 40 kHz, 65% methanol as the solvent, an extraction time of 30 min and an extraction temperature of 40 °C. Using these optimal conditions, the experimental values agreed closely with the predicted values. The analysis of variance (ANOVA indicated a high goodness of model fit and the success of the RSM method for optimizing syringin extraction from the bark of <em>I>. em>rotunda>.

  4. Classe social: conceitos e esquemas operacionais em pesquisa em saude

    Directory of Open Access Journals (Sweden)

    Rita Barradas Barata

    2013-08-01

    Full Text Available Discute-se a utilização do conceito de classe em pesquisas em saúde, as diferentes abordagens sociológicas de estratificação social e de estrutura de classes, o potencial explicativo do conceito em estudos de determinação social e desigualdades em saúde, os modelos de operacionalização elaborados para uso em pesquisas sociológicas, demográficas ou de saúde e os limites e possibilidades desses modelos. Foram destacados quatro modelos de operacionalização: de Singer para estudo da distribuição de renda no Brasil, adaptado por Barros para uso em pesquisas epidemiológicas; de Bronfman & Tuirán para o censo demográfico mexicano, adaptado por Lombardi et al para pesquisas epidemiológicas; de Goldthorpe para estudos socioeconômicos ingleses, adaptado pela Sociedade Espanhola de Epidemiologia; e o modelo de Wright para pesquisa em sociologia e ciência política, também usado em inquéritos populacionais em saúde. Em conclusão, conceitualmente cada um dos modelos apresentados é coerente com a concepção teórica que os embasam, mas não há como optar por qualquer deles, descartando os demais.

  5. Efecto de extractos vegetales de <em>Polygonum hydropiperoidesem>, <em>Solanum nigrumem> y <em>Calliandra pittieriem> sobre el gusano cogollero (<em>Spodoptera frugiperdaem>

    Directory of Open Access Journals (Sweden)

    Lizarazo H. Karol

    2008-12-01

    Full Text Available

    El gusano cogollero <em>Spodoptera frugiperdaem> es una de las plagas que más afectan los cultivos en la región de Sumapaz (Cundinamarca, Colombia. En la actualidad se controla principalmente aplicando productos de síntesis química, sin embargo la aplicación de extractos vegetales surge como una alternativa de menor impacto sobre el ambiente. Este control se emplea debido a que las plantas contienen metabolitos secundarios que pueden inhibir el desarrollo de los insectos. Por tal motivo, la presente investigación evaluó el efecto insecticida y antialimentario de extractos vegetales de barbasco <em>Polygonum hydropiperoidesem> (Polygonaceae, carbonero <em>Calliandra pittieriem> (Mimosaceae y hierba mora <em>Solanum nigrumem> (Solanaceae sobre larvas de <em>S. frugiperdaem> biotipo maíz. Se estableció una cría masiva del insecto en el laboratorio utilizando una dieta natural con hojas de maíz. Posteriormente se obtuvieron extractos vegetales utilizando solventes de alta polaridad (agua y etanol y media polaridad (diclorometano los cuales se aplicaron sobre las larvas de segundo instar. Los resultados más destacados se presentaron con extractos de <em>P. hydropiperoidesem>, obtenidos con diclorometano en sus diferentes dosis, con los cuales se alcanzó una mortalidad de 100% 12 días después de la aplicación y un efecto antialimentario representado por un consumo de follaje de maíz inferior al 4%, efectos similares a los del testigo comercial (Clorpiriphos.

  6. Prima segnalazione di <em>Brachylaima fulvusem> Dujardin, 1843 (Digenea, Brachylaimidae in <em>Sorex> cfr. <em>antinorii> Bonaparte, 1848 (Insectivora, Soricidae in Italia

    Directory of Open Access Journals (Sweden)

    Juan Carlos Casanova

    2003-10-01

    Full Text Available Un?indagine parassitologica è stata condotta su esemplari di <em>Sorex> cfr. <em>antinorii> Bonaparte, 1840 (Insectivora, Soricidae catturati in Sila Grande (Valle Capra; 16.29.30; 39.21.40. Uno degli esemplari è stato trovato parassitato da Trematodi digenei rinvenuti nell?esofago e nello stomaco. I parassiti isolati sono stati fissati con liquido di Bouin, colorati con carminio acetico di Semichon, fissati in una serie di alcooli, chiarificati in xilolo e montati con Balsamo del Canada. I parassiti sono stati identificati come membri della Famiglia Brachylaimidae Joyeux & Foley (1930 appartenenti al genere <em>Brachylaima> Dujardin (1843. La morfologia generale ed i caratteri metrici hanno permesso di identificarli come <em>B. fulvusem> Dujardin, 1843 (lunghezza corpo: 2.39-2.46; larghezza corpo: 0.72-0.78; diametro trasversale ventosa orale: 212.48- 238.08x240.64-266.24; ventosa ventrale: 250.88-258.56x250.88-266.24; faringe 120.32-168.96; testicoli: 151.04-189.44x168.96-189.44; ovario: 122.88x171.52; uova: 26-30x2-17. Il range dei dati morfometrici coincide con quelli riscontrati da diversi autori negli esemplari di <em>B. fulvusem> in Europa centrale e occidentale (Jourdane, 1971; Lewis, 1969; Zarnowski,1960; Mas-Coma & Gallego, 1975. Dopo la descrizione originale, la sistematica di <em>B. fulvusem> Blanchard, 1847 non è stata mai confutata, sebbene varie specie dei generi <em>Harmostomum> Braun, 1899 e <em>Panopistus Sinitzinem>, 1931 siano state proposte come sinonimi di <em>B. fulvusem> da diversi autori. Zarnowski (1960 considera aperta la questione di identità di <em>H. (H. dujardiniem> Baer, 1928 e propone la sinonimia di <em>B. oesophageiem> Shaldibin, 1953 e <em>B. fulvusem>. Lewis (1969, al contrario, ha riconvalidato <em>B. oesophageiem> come specie, utilizzando criteri che, però, Jourdane (1971 ritiene, non idonei a differenziare le due specie. Mas-Coma & Gallego (1975, considerano <em

  7. <em>Bacillus anthracisem> Factors for Phagosomal Escape

    Directory of Open Access Journals (Sweden)

    Irene Zornetta

    2012-07-01

    Full Text Available The mechanism of phagosome escape by intracellular pathogens is an important step in the infectious cycle. During the establishment of anthrax, <em>Bacillus anthracisem> undergoes a transient intracellular phase in which spores are engulfed by local phagocytes. Spores germinate inside phagosomes and grow to vegetative bacilli, which emerge from their resident intracellular compartments, replicate and eventually exit from the plasma membrane. During germination, <em>B. anthracisem> secretes multiple factors that can help its resistance to the phagocytes. Here the possible role of <em>B. anthracisem> toxins, phospholipases, antioxidant enzymes and capsules in the phagosomal escape and survival, is analyzed and compared with that of factors of other microbial pathogens involved in the same type of process.

  8. Facetas em dentes anteriores

    OpenAIRE

    Veloso, Helena Rafaela Lourenço Martins

    2015-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária A presente revisão bibliográfica aborda as facetas estéticas em dentes anteriores, pela crescente valorização de um sorriso esteticamente agradável, facto que faz com que as pessoas procurem cada vez mais alternativas de tratamento para melhorar a aparência do seu sorriso. Os dentes anteriores são decisivos na aparência estética e, c...

  9. EMS & the DEA.

    Science.gov (United States)

    Beeson, Jeff; Ayres, Chris

    2010-01-01

    It's clear that EMS medical directors and management staff must be vigilant in their oversight of implementation, administration and monitoring of controlled substances within their agencies to best serve the public and avoid running afoul of investigation and incurring significant penalties. Those potentially affected by the need for individual registrations of both emergency vehicles and central inventory systems should carefully monitor upcoming developments in the interpretation od DEA regulations.

  10. CORANTES ARTIFICIAIS EM ALIMENTOS

    Directory of Open Access Journals (Sweden)

    Marcelo Alexandre PRADO

    2009-07-01

    Full Text Available

    O emprego de aditivos químicos é, sem dúvida, um dos mais polêmicos avanços alcançados pela indústria de alimentos. Os corantes artificiais pertencem a uma dessas classes de aditivos alimentares e têm sido objeto de muitas críticas, já que seu uso em muitos alimentos justifica-se apenas por questões de hábitos alimentares. Ainda existem diferentes opiniões quanto à inocuidade dos diversos corantes artificiais. Visando, principalmente, o controle no uso dos corantes sintéticos, mas tendo em vista que produtos coloridos artificialmente são exportados e importados, a análise desses aditivos requer métodos eficientes e rápidos para a detecção, identificação e quantificação. A cromatografia em papel e em camada delgada, apesar de serem técnicas relativamente rápidas, apresentam dados com baixa exatidão e precisão. Já na cromatografia líquida de alta eficiência (CLAE as maiores dificuldades encontram-se nas etapas de extração, mas principalmente no alto custo do equipamento. A eletroforese capilar apresenta os mesmos problemas da CLAE, aliados ao fato de se tratar de uma técnica relativamente recente para a análise desse tipo de substância e, portanto, existem poucos estudos a cerca da determinação e quantificação. PALAVRAS-CHAVE: Corantes artificiais; análise; legislação; CLAE; EC

  11. Bacharelado em Psicopedagogia

    OpenAIRE

    Ramos, Maria Beatriz Jacques; PUCRS

    2007-01-01

    Este texto mostra a história da implantação do Curso de Bacharelado em Psicopedagogia na FACED, PUCRS. Neste texto são apresentados os referenciais teóricos e dados sobre a atuação do psicopedagogo nos campos preventivo e terapêutico explicitando a relevância da formação de profissionais nesta área. Descritores – Psicopedagogia; aprendizagem; problema de aprendizagem.

  12. On subspecific taxonomy of <em>Microtus saviiem> (Rodentia, Arvicolidae

    Directory of Open Access Journals (Sweden)

    Longino Contoli

    2003-10-01

    Full Text Available Riassunto Sulla tassonomia sottospecifica di <em>Microtus saviiem> (Rodentia, Arvicolidae Viene riveduta e riassunta la situazione tassonomica sottospecifica di <em>Microtus (Terricola saviiem>, anche tramite la descrizione di due nuovi taxa: <em>Microtus (Terricola savii tolfetanusem>, dei Monti della Tolfa e <em>Microtus (Terricola savii niethammericusem>, del Gargano.

  13. How <em>Varroa> Parasitism Affects the Immunological and Nutritional Status of the Honey Bee, <em>Apis melliferaem>

    Directory of Open Access Journals (Sweden)

    Katherine A. Aronstein

    2012-06-01

    Full Text Available We investigated the effect of the parasitic mite <em>Varroa destructorem> on the immunological and nutritional condition of honey bees, <em>Apis melliferaem>, from the perspective of the individual bee and the colony. Pupae, newly-emerged adults and foraging adults were sampled from honey bee colonies at one site in S. Texas, USA. <em>Varroa>‑infested bees displayed elevated titer of Deformed Wing Virus (DWV, suggestive of depressed capacity to limit viral replication. Expression of genes coding three anti-microbial peptides (<em>defensin1, abaecin, hymenoptaecinem> was either not significantly different between <em>Varroa>-infested and uninfested bees or was significantly elevated in <em>Varroa>-infested bees, varying with sampling date and bee developmental age. The effect of <em>Varroa> on nutritional indices of the bees was complex, with protein, triglyceride, glycogen and sugar levels strongly influenced by life-stage of the bee and individual colony. Protein content was depressed and free amino acid content elevated in <em>Varroa>-infested pupae, suggesting that protein synthesis, and consequently growth, may be limited in these insects. No simple relationship between the values of nutritional and immune-related indices was observed, and colony-scale effects were indicated by the reduced weight of pupae in colonies with high <em>Varroa> abundance, irrespective of whether the individual pupa bore <em>Varroa>.

  14. Pseudomembranous collagenous colitis with superimposed drug damage.

    Science.gov (United States)

    Villanacci, Vincenzo; Cristina, Silvia; Muscarà, Maurizio; Saettone, Silvia; Broglia, Laura; Antonelli, Elisabetta; Salemme, Marianna; Occhipinti, Pietro; Bassotti, Gabrio

    2013-11-01

    Pseudomembranous collagenous colitis is a rare pathological condition, not related to infectious agents, and characterized by thickening of the subepithelial collagen and formation of pseudomembranes. We report one such case, which responded to budesonide treatment after failures of previous approaches given, being unaware of the correct diagnosis.

  15. Superimposed particles in 1D ground states

    Energy Technology Data Exchange (ETDEWEB)

    Sueto, Andras, E-mail: suto@szfki.hu [Research Institute for Solid State Physics and Optics, Hungarian Academy of Sciences, PO Box 49, H-1525 Budapest (Hungary)

    2011-01-21

    For a class of nonnegative, range-1 pair potentials in one-dimensional continuous space we prove that any classical ground state of lower density {>=}1 is a tower-lattice, i.e. a lattice formed by towers of particles the heights of which can differ only by 1, and the lattice constant is 1. The potential may be flat or may have a cusp at the origin; it can be continuous, but its derivative has a jump at 1. The result is valid on finite intervals or rings of integer length and on the whole line.

  16. Controlled acceleration of superimposed Bessel beams

    CSIR Research Space (South Africa)

    Dudley, Angela L

    2013-06-01

    Full Text Available when the rotation rate decreases. The change in overall intensity of the two parts of the intensity profile are out of phase with one another. This is a consequence of energy conservation. Consequently, the velocity and acceleration are (4) and (5... in the centre (green) and outer (blue) regions of the intensity profile as a function of the propagation distance, z. (b) Snap-shots of the field recorded at intervals along the propagation distance. Fig. 5. (a) Graph of the velocity of the rotation rate as a...

  17. Research advances of superimposed orogenesis and metallogenesis in the Sanjiang Tethys%三江特提斯复合造山与成矿作用研究进展

    Institute of Scientific and Technical Information of China (English)

    邓军; 杨立强; 王长明

    2011-01-01

    The significant achievements in past three - year of superimposed orogenesis and metallogenesis in the Sanjiang Tethys, the National 973-Program, are briefly summarized in this paper, including the metallogenic geodynamic setting, the metallogenic systems of accreting orogen and collisional orogen, the transition of tectonic regime and superimposed orogenesis, the metallogenic forecasting theory and the exploration techniques. (1) The metallogenic geodynamic getting of the proto-, paleo-, neo-Tethys and continental collision have been built up, and the large-scale tectonics-magmatism-metallogenic event during the Yanshanian has been proposed. (2) VMS Cu-Pb-Zn metallogenic systems have been divided into three types; the passive continental margin type, the active continental margin type, and ocean basin type. Studies showed that the metallogenesis in the Yulong and Xianggelila porphyry Cu metallogenic belt was related to the Indian magmatic activities. (3) Sediment-hosted Pb-Zn-Cu-Ag deposits formed at the three stages of the Indo-Asia collisional orogen, which include two metallogenic systems: the vein Cu systems are related to metamorphic fluids from both of the deep crust and shallow sedimentary strata, and Pb-Zn-Cu-Ag systems are related to basin fluids from the shallow sedimentary strata. (4) Porphyry Cu metallogenic system in the Jinshajiang-Ailaoshan belt formed in the age of 35Ma ± , which is controlled by the crust thickness from the Indo-Asia collisional orogen. (5 ) Orogenic gold deposits occurred in three tectonic-thermal events; the earlier convergence regime of India-Eurasia at 62Ma ± , and the transition of tectonic regime at the later stage of 35Ma ± and 28Ma. (6) There have been occurred three stages of the transition of tectonic regime in the Sanjiang Tethys; from the accreting orogen to the collisional orogen, from the main collision to late collision, and from late collision to post-collision. The former two controlled the formation of

  18. 混沌神经网络在分离叠加模式和多对多联想记忆中的应用%A Chaotic Neural Network and its Applications in Separation of Superimposed Pattern and Many-to-Many Associative Memory

    Institute of Scientific and Technical Information of China (English)

    刘光远; 段书凯

    2003-01-01

    In this paper, we propose a modified chaotic associative memory neural network(MCAM). It has two im-portant features :it can recall stored patterns from superimposed input; (2)it can deal with many-to-many associativememory. The computer simulations show the effectiveness of the proposed model.

  19. Synthesis and Spectroscopic Analysis of Novel 1<em>H-Benzo[d>]imidazoles Phenyl Sulfonylpiperazines

    Directory of Open Access Journals (Sweden)

    Amjad M. Qandil

    2012-05-01

    Full Text Available A group of benzimidazole analogs of sildenafil, 3-benzimidazolyl-4-methoxy-phenylsulfonylpiperazines 2–4 and 3-benzimidazolyl-4-methoxy-<em>N,N>-dimethyl- benzenesulfonamide (5, were efficiently synthesized. Compounds 2–5 were characterized by NMR and MS and contrary to the reported mass spectra of sildenafil, the spectra of the piperazine-containing compounds 2–4 showed a novel fragmentation pattern leading to an <em>m/z> = 316. A mechanism for the formation of this fragment was proposed.

  20. Isolation and Characterization of Microsatellite Markers in Brown Planthopper (<em>Nilaparvata em>lugens> Stål

    Directory of Open Access Journals (Sweden)

    Guangcun He

    2012-07-01

    Full Text Available Brown planthopper (<em>Nilaparvata lugensem> Stål (Homoptera: Delphacidae is an economically important pest on rice. In this study, 30 polymorphic microsatellite markers were developed from <em>N. lugensem> genomic libraries using the method of Fast Isolation by AFLP of Sequence Containing Repeats (FIASCO. Polymorphism of each locus was detected in 48 individuals from two natural populations. These microsatellite loci revealed 2 to 18 alleles, and the expected and observed heterozygosities ranged from 0.042 to 0.937 and from 0.042 to 0.958, respectively. These markers will be useful for the future study of this agricultural pest in population genetics and molecular genetics.

  1. Negative-Pressure Cavitation Extraction of Four Main Vinca Alkaloids from <em>Catharanthus em>roseus> Leaves

    OpenAIRE

    Yuangang Zu; Xiaorui Guo; Yujie Fu; Meng Luo; Wei Wang; Liuqing Yang; Fansong Mu

    2012-01-01

    In the present study, an improved method termed negative-pressure cavitation extraction (NPCE) followed by reverse phase high-performance liquid chromatography (RP-HPLC) was developed for the extraction and quantification of vindoline (VDL), catharanthine (CTR), vincristine (VCR) and vinblastine (VLB) from <em>Catharanthus roseus em>leaves. The optimized method employed 60-mesh particles, 80% ethanol, a negative pressure of −0.075 MPa, a solid to liquid ratio of 1:20, 30 min of ...

  2. Proximate Composition, Nutritional Attributes and Mineral Composition of <em>Peperomia> <em>pellucida> L. (Ketumpangan Air Grown in Malaysia

    Directory of Open Access Journals (Sweden)

    Maznah Ismail

    2012-09-01

    Full Text Available This study presents the proximate and mineral composition of <em>Peperomia> <em>pellucida> L., an underexploited weed plant in Malaysia. Proximate analysis was performed using standard AOAC methods and mineral contents were determined using atomic absorption spectrometry. The results indicated <em>Peperomia> <em>pellucida> to be rich in crude protein, carbohydrate and total ash contents. The high amount of total ash (31.22% suggests a high-value mineral composition comprising potassium, calcium and iron as the main elements. The present study inferred that <em>Peperomia> <em>pellucida> would serve as a good source of protein and energy as well as micronutrients in the form of a leafy vegetable for human consumption.

  3. Casca de soja em dietas para coelhos em crescimento

    Directory of Open Access Journals (Sweden)

    Ana Carolina Kohlrausch Klinger

    2015-01-01

    Full Text Available O presente trabalho teve como objetivo avaliar efeitos da inclusão de casca de soja em substituição ao feno de alfafa sobre o desempenho, características da carcaça e trato gastrointestinal e parâmetros bioquímicos de coelhos em fase de crescimento. Foram utilizados 30 coelhos da raça Nova Zelândia Branca, divididos igualmente em três tratamentos, compostos pela dieta experimental padrão (sem inclusão de casca de soja; e pelas dietas com 50% e 100% de substituição de alfafa por casca de soja nas respectivas rações experimentais. Concluiu-se que a casca de soja pode ser incluída em dietas para coelhos em crescimento, em substituição ao feno de alfafa em até 100% sem causar danos no desempenho nas características de carcaça e do trato gastrointestinal e parâmetros bioquímicos dos animais, durante a fase de crescimento. Porém, a utilização deste co-produto exige a necessidade de estudos mais aprofundados em virtude da escassez de dados.

  4. Antioxidant Profile of <em>Trifolium pratenseem> L.

    Directory of Open Access Journals (Sweden)

    Heidy Schwartsova

    2012-09-01

    Full Text Available In order to examine the antioxidant properties of five different extracts of <em>Trifolium pratenseem> L. (Leguminosae leaves, various assays which measure free radical scavenging ability were carried out: 1,1-diphenyl-2-picrylhydrazyl, hydroxyl, superoxide anion and nitric oxide radical scavenger capacity tests and lipid peroxidation assay. In all of the tests, only the H2O and (to some extent the EtOAc extracts showed a potent antioxidant effect compared with BHT and BHA, well-known synthetic antioxidants. In addition, <em>in vivo em>experiments were conducted with antioxidant systems (activities of GSHPx, GSHR, Px, CAT, XOD, GSH content and intensity of LPx in liver homogenate and blood of mice after their treatment with extracts of <em>T. pratenseem> leaves, or in combination with CCl4. Besides, in the extracts examined the total phenolic and flavonoid amounts were also determined, together with presence of the selected flavonoids: quercetin, luteolin, apigenin, naringenin and kaempferol, which were studied using a HPLC-DAD technique. HPLC-DAD analysis showed a noticeable content of natural products according to which the examined <em>Trifolium pratenseem> species could well be regarded as a promising new source of bioactive natural compounds, which can be used both as a food supplement and a remedy.

  5. Identification and Characterization of a <em>Bursaphelenchus xylophilusem> (Aphelenchida: Aphelenchoididae Thermotolerance-Related Gene: <em>Bx-HSP90em>

    Directory of Open Access Journals (Sweden)

    Danlei Li

    2012-07-01

    Full Text Available Temperatures directly influence the distribution and intensity of pine wilt disease caused by the pine wood nematode, <em>Bursaphelenchus xylophilusem>. To date, however, little is known about the causation and mechanism of this influence. The molecular chaperone HSP90 is a key component that contributes to survival in the abiotic stress response. In this study, we investigated the relationship between the survival of <em>B. xylophilusem> and the functionality of the HSP90 gene<em>.> <em>Bx-HSP90 em>was cloned from a suppression subtractive hybridization library. <em>In situem> mRNA hybridization showed that <em>Bx-HSP90em> was constitutively expressed in response to all of the temperatures tested, and RT-PCR indicated that all of the temperatures could induce <em>Bx-HSP90 em>transcription, with the highest transcript level detected at 30 °C. The suppression of the <em>Bx-HSP90em> transcript by RNA interference led to a 25% reduction in the number of nematodes at 30 °C after 44 h. Sharp declines in the survival of the RNAi-treated nematodes were observed after 8 days at 25 °C, 48 h at 30 °C and 24 h at 35 °C. Both heat shock and the knockdown of <em>Bx-HSP90 em>hindered the growth of the <em>B. xylophilusem> populations. The results indicate that <em>Bx-HSP90em> is essential for the survival of <em>B. xylophilusem>, confirming the thermoregulatory function of the gene, and delineate the timeframe and temperature range within which the gene function occurs.

  6. Effects of <em>Citrus aurantiumem> (Bitter Orange Fruit Extracts and <em>p>-Synephrine on Metabolic Fluxes in the Rat Liver

    Directory of Open Access Journals (Sweden)

    Rosane Marina Peralta

    2012-05-01

    Full Text Available The fruit extracts of <em>Citrus aurantiumem> (bitter orange are traditionally used as weight-loss products and as appetite supressants. An important fruit component is <em>p>-synephrine, which is structurally similar to the adrenergic agents. Weight-loss and adrenergic actions are always related to metabolic changes and this work was designed to investigate a possible action of the <em>C. aurantiumem> extract on liver metabolism. The isolated perfused rat liver was used to measure catabolic and anabolic pathways, including oxygen uptake and perfusion pressure. The <em>C. aurantiumem> extract and <em>p>-synephrine increased glycogenolysis, glycolysis, oxygen uptake and perfusion pressure. These changes were partly sensitive to a- and b-adrenergic antagonists. <em>p>-Synephrine (200 mM produced an increase in glucose output that was only 15% smaller than the increment caused by the extract containing 196 mM <em>p>-synephrine. At low concentrations the <em>C. aurantiumem> extract tended to increase gluconeogenesis, but at high concentrations it was inhibitory, opposite to what happened with <em>p>-synephrine. The action of the <em>C. aurantiumem> extract on liver metabolism is similar to the well known actions of adrenergic agents and can be partly attributed to its content in <em>p>-synephrine. Many of these actions are catabolic and compatible with the weight-loss effects usually attributed to <em>C. aurantiumem>.

  7. Nanodispositivos baseados em grafeno

    OpenAIRE

    José Eduardo Padilha de Sousa

    2012-01-01

    Nesta tese investigamos a partir de cálculos de primeiros princípios, dispositivos e componentes de dispositivos baseados em grafeno. Abordamos os campos da nanoeletrônica e da spintrônica. Dentro da nanoeletrônica investigamos: (i) propriedades de transporte de um nanotransistor de bicamada de grafeno na presença de um gate duplo. Demonstramos que sobre a ação de um campo elétrico externo, mesmo utilizando um gate da ordem de 10 nm, à temperatura ambiente e 4.5K uma corrente nula nunca é exi...

  8. Sade em Lacan

    OpenAIRE

    Riaviz, Eduardo

    2000-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Esta dissertação analisa o lugar do Marquês de Sade no ensino de Lacan. Começamos por reconstruir a recepção de Sade pela vanguarda francesa, particularmente no movimento surrealista e nos seus dissidentes. Em seguida, acompanhamos as modificações do lugar de Sade na obra de Lacan. Para isto nos orientamos nos seis paradigmas do gozo através dos quais J.-A. Miller ordena a doutrina lacaniana...

  9. Flashes em Circuito

    Directory of Open Access Journals (Sweden)

    Ivete Lara Camargos Walty

    2002-12-01

    Full Text Available Reflexão sobre o papel da narrativa urbana no tratamento do tema da exclusão social, tendo como ponto de partida uma leitura do livro Passaporte, de Fernando Bonassi, que envolve a discussão do próprio gênero, a partir, sobretudo, da teoria do conto de Ricardo Piglia e de sua retomada das Seis propostas para o próximo milênio, de Ítalo Calvino, em artigo recente.

  10. Perspectives on EM metamaterials

    Directory of Open Access Journals (Sweden)

    Christophe Caloz

    2009-03-01

    Full Text Available Electromagnetic (EM metamaterials have become a field of intense research activities. This paper presents a critical perspective of the field, with emphasis on fundamental concepts and practical applications. Metamaterials are explained in the general context of periodic structures. Resonant particle type and transmission line type metamaterials are compared, and their fundamental connection is established. Exotic phenomena recently reported and associated challenges are briefly reviewed. Practical applications are enumerated and illustrated by an example. The paper concludes with an optimistic outlook regarding the future of metamaterials.

  11. Anestesia Diploica em Endodontia

    OpenAIRE

    Macedo, Ricardo Ribeiro Veiga de

    2013-01-01

    Trabalho final do 5º ano com vista à atribuição do grau de mestre no âmbito do ciclo de estudos de Mestrado Integrado em Medicina Dentária apresentado à Faculdade de Medicina da Universidade de Coimbra. Objetivos Comparar a eficácia das técnicas de anestesia convencionais, a anestesia infiltrativa periapical, com a anestesia diploica. Metodologia Foram selecionados 32 voluntários, saudáveis, aos quais foram administradas ambas as técnicas anestésicas no dente 1.4. Numa primeira fase os...

  12. Perossomus elumbis em bovino

    OpenAIRE

    1986-01-01

    Relato de um caso de distocia fetal em uma fêmea bovina mestiça Holandesa)Gir, provocado pela presença do monstro fetal Perossomus elumbis. Foi observado que o monstro fetal apresentava agenesia de vértebras lombares e coccígeas, com hi-poplasia da medula vertebral, terminando na região das últimas vértebras torácicas. A pelve apresentava-se hipoplásica com estreitamento do canal pélvico e anquilose dos membros posteriores e articulações da bacia, bem como atrofia muscular.  

  13. A New Benzofuran Derivative from <em>Flemingia philippinensisem> Merr. et Rolfe

    Directory of Open Access Journals (Sweden)

    Hua Li

    2012-06-01

    Full Text Available A new prenylated benzofuran derivative, named flemiphilippinone A, was isolated together with ten known flavonoids from the roots of <em>Flemingia philippinensisem>. Flemiphilippinone A was identified as (2<em>S>,3a<em>S>-5-(1-hydroxy-3-(4-methoxyphenyl- propylidene-2-(2-hydroxypropan-2-yl-3a,7-bis(3-methylbut-2-en-1-yltetrahydrobenzo- furan-4,6(2<em>H>,5<em>H>-dione, and its structure was established by a combination of HR EIMS, 1H-NMR, 13C-NMR, HMQC, HMBC and NOESY spectra data.

  14. O insight em psiquiatria

    Directory of Open Access Journals (Sweden)

    Ana Margarida P. Cardoso

    2008-12-01

    Full Text Available O sinal de que algo está a acontecer contribui para que o paciente reconheça que alguma coisa de estranho se está a passar consigo. Este reconhecimento faz com que o sujeito possa desempenhar uma função activa e seja um elemento colaborante do seu processo de recuperação. Cada doença apresenta, contudo, diferentes sintomas, uma vez que cada doença psiquiátrica consiste em diferentes perturbações com diversos efeitos sobre o funcionamento mental. Desta maneira, o fenómeno do insight que é registado em cada doença é diferente e expressa-se sob diferentes formas, não somente devido às manifestações clínicas da doença mas também devido às características individuais do sujeito.

  15. Antibioticos profilaticos em neurocirurgia

    Directory of Open Access Journals (Sweden)

    Reynaldo A. Brandt

    1979-03-01

    Full Text Available O índice de infecções pós-operatórias em pacientes neuro-cirúrgicos que receberam antibióticos profiláticos neste período foi comparado com o de pacientes que não receberam antibióticos. Infecções ocorreram em proporções significativamente maiores nos pacientes que receberam antibióticos, particularmente naqueles com afecções intracranianas graves; estas infecções foram graves e fatais na maioria dos casos. A administração de antibióticos profiláticos nestes pacientes não só foi incapaz de prevenir o aparecimento de infecções pós-operatórias, como aparentemente favoreceu o seu desenvolvimento. Tal se deveu, provavelmente, à destruição do equilíbrio microbiano no organismo, favorecendo o desenvolvimento de germes patogênicos e resistentes aos antibióticos usuais

  16. DYNAMIC SYSTEM COLLISION,SUPERIMPOSING AND GOLD DEPOSIT FORMING IN JIAPIGOU FAULT BELT,JILIN PROVINCE%吉林夹皮沟断裂带动力系统碰撞、叠加及金矿床形成

    Institute of Scientific and Technical Information of China (English)

    孙忠实; 冯本智; 邓军; 翟裕生

    2001-01-01

    Dynamic system is the sdudying key in gold metallization. Itcontrols gold deposit forming all the time. Earth evolution and gold metallization in Jiapigou area are divided into three stages and three kinds of tectonic belts with the help of metallogenic dynamic system theory. The first one is the marginal gold mineralizing belt of rising-slipping dynamic system in the Archean-Proterozoic craton. A pair of dynamic system between uplifting Archean craton and extending or slipping Proterozoic sediments formed gold mineralizing ductile shear belts of the craton margin and then gold enriched initially. Dynamic system of the hercynian subduction is the second kind of the south margin mineralizing belt. Continental rift and collision took place between Siberia plate and Chinese-Korea plate. The positive-negative dynamic system formed over earth crust-fault and gold mineralizes.The Mesozoic superimposing tectono-magmatic dynamic system forms the third kind of metallogenic belt. The Mesozoic Pacific plate subduction, TanLu fault slipping , NNE and NW striked conjugate ore-controlling structure form poly-level dynamic system superimposing. Magma activities and mantle origin fluid go up. Gold further enrich. Finally form Jiapigou gold deposit.The limits of metallogenic prognosis are that original metamorphic rock's area enter Jiapigou fault belt and the Mesozoic granite area by both sides of Jiapigou fault.%动力系统是金成矿作用研究的关键,它控制金矿床产生的始终。运用成矿动力系统思想把夹皮沟区地壳演化和金成矿分为三大阶段和三大构造带。(1)太古—元古宙克拉通隆—滑动力系统边缘矿化带,太古宙克拉通隆起、元古宙沉积物拉伸滑断,成矿动力系统在克拉通周边形成韧性剪切带,金受到初步富集;(2)海西俯冲动力系统南缘矿化带,西伯利亚板块与中朝板块间大陆拉张和碰撞,正反动力系统产生超壳断裂和金矿化;(3)中生代叠

  17. <em>Ipomoea aquaticaem> Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity

    OpenAIRE

    Hadi, A. Hamid A.; Siddig Ibrahim Abdelwahab; Suzy Munir Salama; Salim Said Alkiyumi; Mahmood Ameen Abdullah; Ahmed Salim Alrashdi

    2012-01-01

    In the Indian system of traditional medicine (Ayurveda) it is recommended to consume <em>Ipomoea em>aquatica> to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of <em>I. aquaticaem> against liver damage were evaluated in thioacetamide (TAA)-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD) rats were orally fed with <em>...

  18. Four Novel Cellulose Synthase (CESA Genes from <em>Birch> (<em>Betula platyphylla em>Suk. Involved in Primary and Secondary Cell Wall Biosynthesis

    Directory of Open Access Journals (Sweden)

    Xuemei Liu

    2012-09-01

    Full Text Available Cellulose synthase (CESA, which is an essential catalyst for the generation of plant cell wall biomass, is mainly encoded by the <em>CesA> gene family that contains ten or more members. In this study; four full-length cDNAs encoding CESA were isolated from<em> Betula platyphyllaem> Suk., which is an important timber species, using RT-PCR combined with the RACE method and were named as <em>BplCesA3em>, <em>−4em>,> −7 em>and> −8em>. These deduced CESAs contained the same typical domains and regions as their <em>Arabidopsis> homologs. The cDNA lengths differed among these four genes, as did the locations of the various protein domains inferred from the deduced amino acid sequences, which shared amino acid sequence identities ranging from only 63.8% to 70.5%. Real-time RT-PCR showed that all four <em>BplCesAs> were expressed at different levels in diverse tissues. Results indicated that BplCESA8 might be involved in secondary cell wall biosynthesis and floral development. BplCESA3 appeared in a unique expression pattern and was possibly involved in primary cell wall biosynthesis and seed development; it might also be related to the homogalacturonan synthesis. BplCESA7 and BplCESA4 may be related to the formation of a cellulose synthase complex and participate mainly in secondary cell wall biosynthesis. The extremely low expression abundance of the four BplCESAs in mature pollen suggested very little involvement of them in mature pollen formation in <em>Betula>. The distinct expression pattern of the four <em>BplCesAs> suggested they might participate in developments of various tissues and that they are possibly controlled by distinct mechanisms in <em>Betula.>

  19. <em>N>-Substituted 5-Chloro-6-phenylpyridazin-3(2<em>H>-ones: Synthesis, Insecticidal Activity Against <em>Plutella xylostella em>(L. and SAR Study

    Directory of Open Access Journals (Sweden)

    Song Yang

    2012-08-01

    Full Text Available A series of <em>N>-substituted 5-chloro-6-phenylpyridazin-3(2<em>H>-one derivatives were synthesized based on our previous work; all compounds were characterized by spectral data and tested for <em>in vitroem> insecticidal activity against <em>Plutella xylostellaem>. The results showed that the synthesized pyridazin-3(2<em>H>-one compounds possessed good insecticidal activities, especially the compounds 4b, 4d, and 4h which showed > 90% activity at 100 mg/L. The structure-activity relationships (SAR for these compounds were also discussed.

  20. INFLUÊNCIA ESTOICA NA CONCEPÇÃO DE <em>STATUS> E <em>DICTUM> COMO <em> QUASI RES EM> (ὡσανεì τινά) EM ABERLARDO STOIC INFLUENCE IN ABELARD'S CONCEPTION OF <em>STATUS> AND <em>DICTUM> AS <em>QUASI RESem> (ὡσανεì τινά).

    OpenAIRE

    Guy Hamelin

    2011-01-01

    Na sua obra, Pedro Abelardo (1079-1142) destaca duas noções metafísicas que fundamentam sua teoria lógica: o <em style="mso-bidi-font-style: normal;">statusem> e o <em style="mso-bidi-font-style: normal;">dictum propositionisem>, ao causar, respectivamente, a imposição (<em style="mso-bidi-font-style: normal;">impositioem>) dos termos universais e o valor de verdade das proposições. Trata-se de expressões que se referem a naturezas ontológicas peculia...

  1. Acute electromyostimulation decreases muscle sympathetic nerve activity in patients with advanced chronic heart failure (EMSICA Study.

    Directory of Open Access Journals (Sweden)

    Marc Labrunée

    Full Text Available BACKGROUND: Muscle passive contraction of lower limb by neuromuscular electrostimulation (NMES is frequently used in chronic heart failure (CHF patients but no data are available concerning its action on sympathetic activity. However, Transcutaneous Electrical Nerve Stimulation (TENS is able to improve baroreflex in CHF. The primary aim of the present study was to investigate the acute effect of TENS and NMES compared to Sham stimulation on sympathetic overactivity as assessed by Muscle Sympathetic Nerve Activity (MSNA. METHODS: We performed a serie of two parallel, randomized, double blinded and sham controlled protocols in twenty-two CHF patients in New York Heart Association (NYHA Class III. Half of them performed stimulation by TENS, and the others tested NMES. RESULTS: Compare to Sham stimulation, both TENS and NMES are able to reduce MSNA (63.5 ± 3.5 vs 69.7 ± 3.1 bursts / min, p < 0.01 after TENS and 51.6 ± 3.3 vs 56.7 ± 3.3 bursts / min, p < 0, 01 after NMES. No variation of blood pressure, heart rate or respiratory parameters was observed after stimulation. CONCLUSION: The results suggest that sensory stimulation of lower limbs by electrical device, either TENS or NMES, could inhibit sympathetic outflow directed to legs in CHF patients. These properties could benefits CHF patients and pave the way for a new non-pharmacological approach of CHF.

  2. Fisioterapia motora em pacientes adultos em terapia intensiva

    OpenAIRE

    Borges,Vanessa Marcos; Oliveira,Luiz Rogério Carvalho de; Peixoto,Elzo; Carvalho, Nilza Aparecida de Almeida

    2009-01-01

    O objetivo desse estudo é realizar uma revisão da literatura abordando o tema fisioterapia motora para pacientes adultos em unidade de terapia intensiva. A busca de artigos científicos foi realizada nas bases de dados PubMed, MedLine (Literatura Internacional em Ciências e Saúde), LILACS (Literatura Latino Americana e do Caribe em Ciências e Saúde) e Cochrane entre 1995 e dezembro de 2008 utilizando as palavras-chaves: physical therapy, mobilization and intensive care unit. Para efeito de com...

  3. Osteoporose em caprinos

    Directory of Open Access Journals (Sweden)

    Fábio B. Rosa

    2013-04-01

    Full Text Available Foi realizado um estudo de casos de osteoporose em caprinos provenientes de uma propriedade na área de abrangência do LPV-UFSM, determinando a epidemiologia, o quadro clínico-patológico e discutindo os prováveis mecanismos patogenéticos. Cinco cabras, fêmeas, SRD, de seis meses a seis anos de idade foram afetadas. As cabras eram mantidas em campo nativo, sem suplementação com ração e sob superlotação. Os principais sinais clínicos foram emagrecimento, dificuldade de locomoção e permanência em decúbito por longos períodos. As principais alterações macroscópicas nos ossos examinados foram vistas nas superfícies de corte e caracterizavam-se por depleção do osso esponjoso (porosidade e redução acentuada da espessura do osso cortical. Havia também marcada atrofia serosa da gordura da medula óssea. Microscopicamente, nas regiões avaliadas (úmero proximal, rádio distal, fêmur distal, tíbia proximal e corpos das vértebras lombares foi observada redução moderada a acentuada do número e da espessura das trabéculas ósseas nas epífises e metáfises dos ossos longos e nos corpos vertebrais. Os achados clínico-patológicos indicaram que a osteoporose observada provavelmente foi causada pela desnutrição. As alterações ósseas (diminuição no número e na espessura das trabéculas do osso esponjoso sugerem que ambos os mecanismos, má formação óssea e reabsorção óssea aumentada, contribuíram para a ocorrência de osteoporose nos caprinos deste estudo.

  4. INFLUÊNCIA ESTOICA NA CONCEPÇÃO DE <em>STATUS> E <em>DICTUM> COMO <em> QUASI RES EM> (ὡσανεì τινά EM ABERLARDO STOIC INFLUENCE IN ABELARD'S CONCEPTION OF <em>STATUS> AND <em>DICTUM> AS <em>QUASI RESem> (ὡσανεì τινά.

    Directory of Open Access Journals (Sweden)

    Guy Hamelin

    2011-09-01

    Full Text Available Na sua obra, Pedro Abelardo (1079-1142 destaca duas noções metafísicas que fundamentam sua teoria lógica: o <em style="mso-bidi-font-style: normal;">statusem> e o <em style="mso-bidi-font-style: normal;">dictum propositionisem>, ao causar, respectivamente, a imposição (<em style="mso-bidi-font-style: normal;">impositioem> dos termos universais e o valor de verdade das proposições. Trata-se de expressões que se referem a naturezas ontológicas peculiares, na medida em que não são consideradas coisas (<em style="mso-bidi-font-style: normal;">resem>, mesmo que constituem causas. Todavia, também não são nada. Abelardo as chama de ‘quase coisas’ (<em style="mso-bidi-font-style: normal;">quasi resem>. No presente artigo, explicamos, primeiro, essas duas noções essenciais da lógica abelardiana, antes de tentar, em seguida, encontrar a fonte dessa metafísica particular. Em oposição a comentadores importantes da lógica de Abelardo, que estimam que haja uma forte influência platônica sobre essa concepção específica, defendemos antes, com apoio de textos significativos e de acordo com o nominalismo abelardiano, que a maior ascendência sobre a metafísica do nosso autor é a do estoicismo, sobretudo, antigo.In his work, Peter Abelard (1079-1142 highlights two metaphysical notions, which sustain his logical theory: the <em>status> and the <em>dictum propositionisem>, causing respectively both the imposition (<em>impositio> of universal terms and the thuth-value of propositions. Both expressions refer to peculiar ontological natures, in so far as they are not considered things (<em>res>, even if they constitute causes. Nevertheless, neither are they ‘nothing’. Abelard calls them ‘quasi-things’ (<em>quasi resem>. In the present article, we expound first these two essential notions of Abelardian logic before then trying to find the source of this particular metaphysics. Contrary to some important

  5. Em favor da talassografia

    Directory of Open Access Journals (Sweden)

    Jean-Louis Boudou

    2001-01-01

    Full Text Available A Talassografia (“descrição do mar” interessa-sepelos impactos físicos, biológicos, ecológicos... culturais da violenta antropização dos ambientes costeiros (oceânicos e continentais, caracterizados pelaexigüidade, vulnerabilidade, fragilidade e plasticidade. Como o Brasil é um “país marítimo”, os geó-grafos (os talassógrafos brasileiros são convidadosa intensificar suas pesquisas nas áreas costeiras e acriar novas estruturas para divulgá-las: Revista, Encontros, Associação, Pós-Graduação... tudo em prolda talassografia.

  6. Constrangimentos posturais em ergonomia

    OpenAIRE

    Silva, Cláudio Roberto de Carvalho

    2001-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção. A incorporação da Ergonomia no projeto e gerenciamento do consultório odontológico é fundamental, com o objetivo de adequar e adaptar o trabalho ao cirurgião dentista. Neste trabalho de pesquisa, a aplicação de conceitos atuais da Ergonomia se fez necessária para que fosse possível a obtenção de dados para uma análise apurada com relação às posturas ad...

  7. Iatrogenia em cardiologia

    OpenAIRE

    Pereira,Afonso Celso; Franken,Roberto Alexandre; Sprovieri,Sandra Regina Schwarzwalder; Golin,Valdir

    2000-01-01

    O termo iatrogenia vem do grego e refere-se a qualquer alteração patológica provocada no paciente pela má prática médica. Infelizmente, o risco de sua ocorrência convive constantemente no manuseio das doenças cardíacas. Podem ser considerados dois tipos de iatrogenia: iatrogenia de ação, ou decorrente da ação médica, e iatrogenia de omissão, relacionada à falta de ação do médico. As iatrogenias ocorrem em todas as fases do ato médico, desde a relação com o paciente, passando pelo diagnóstico,...

  8. Constrangimentos posturais em ergonomia

    OpenAIRE

    Silva, Cláudio Roberto de Carvalho

    2001-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção. A incorporação da Ergonomia no projeto e gerenciamento do consultório odontológico é fundamental, com o objetivo de adequar e adaptar o trabalho ao cirurgião dentista. Neste trabalho de pesquisa, a aplicação de conceitos atuais da Ergonomia se fez necessária para que fosse possível a obtenção de dados para uma análise apurada com relação às posturas ad...

  9. Marcas culturais em interface

    OpenAIRE

    Mazutti, Sandra

    2011-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Estudos da Tradução A cultura é fator determinante para a língua e, portanto, para todos os atos de compreensão e interpretação da mesma. Língua e cultura estão intrinsecamente interligadas, fazendo parte da identidade não só individual, mas também da sociedade como um todo. Permeando tal relação encontramos o tradutor, que assume o papel de intermediador cultura...

  10. Bullyng em jovens LGBT

    OpenAIRE

    Pimenta, Neuza Santos; Martins, Emíla orient.

    2013-01-01

    O bullying homofóbico é uma forma específica de assédio que ocorre quando a vitimização é motivada pelo preconceito homossexual. Os jovens alunos, lésbicas, gays, bissexuais e transsexuais (LGBT), vítimas desta forma de bullying estão mais vulneráveis à exclusão social, isolamento e aquisição de comportamentos de risco. O presente projeto de investigação pretende contribuir para a compreensão de questões relacionadas com os episódios de bullying em jovens LGBT, sempre na per...

  11. Short and Long-Term Effects of <em>Baccharis articulataem> on Glucose Homeostasis

    Directory of Open Access Journals (Sweden)

    Flávio H. Reginatto

    2012-06-01

    Full Text Available In this study, the<em> in vivoem> effect of the crude extract and <em>n>-butanol and aqueous residual fractions of <em>Baccharis articulataem> (Lam. Pers. on serum glucose levels, insulin secretion and liver and muscle glycogen content, as well as<em> in vitroem> action on serum intestinal disaccharidase activity and albumin glycation were investigated. Oral administration of the extract and fractions reduced glycemia in hyperglycemic rats. Additionally, the <em>n>-butanol fraction, which has high flavonoids content, stimulated insulin secretion, exhibiting an insulinogenic index similar to that of glipizide. Also, the <em>n>-butanol fraction treatment significantly increased glycogen content in both liver and muscle tissue. <em>In vitroem> incubation with the crude extract and <em>n>-butanol and aqueous residual fractions inhibited maltase activity and the formation of advanced glycation end-products (AGEs. Thus, the results demonstrated that <em>B. articulataem> exhibits a significant antihyperglycemic and insulin-secretagogue role. These effects on the regulation of glucose homeostasis observed for <em>B. articulataem> indicate potential anti-diabetic properties.

  12. Preferencia alimenticia del ácaro depredador <em>Balaustium> sp. en condiciones controladas

    Directory of Open Access Journals (Sweden)

    Muñoz Karen

    2009-04-01

    Full Text Available

    Se evaluó la preferencia de presas de <em>Balaustium> sp., enemigo natural de diferentes artrópodos plaga, y el cual es nativo de la Sabana de Bogotá. En unidades experimentales construidas con foliolos de plantas de rosa se colocaron independientemente individuos de <em>Balaustium> sp. y se registró el número de presas consumidas. De esta manera se determinó la preferencia de los tres estados móviles del ácaro depredador <em>Balaustium> sp. por diferentes edades de tres presas. Las especies y edades de las presas estudiadas fueron: huevos, ninfas y adultos de <em>Trialeurodes vaporariorumem>, huevos, ninfas y adultos de <em>Tetranychus urticaeem>, y larvas de primer y segundo instar y adultos de <em>Frankliniella occidentalisem>. Los estados menos desarrollados fueron preferidos, aunque se observó que los adultos del depredador tienen gran habilidad para consumir adultos de <em>T. vaporariorumem>. La presa preferida por las larvas de <em>Balaustium> sp. fue los huevos de <em>T. urticaeem> con una proporción de consumo de 0,54 de los huevos que se ofrecieron de esta presa; las deutoninfas del depredador eligieron huevos de <em>T. vaporariorumem> (0,537 o de <em>T. urticaeem> (0,497 y los adultos de <em>Balaustium> sp. prefrieron los huevos de <em>T. vaporariorumem> (0,588.

  13. Synthesis of 1,2,3-Triazole Derivatives and <em>in Vitroem> Antifungal Evaluation on <em>Candida> Strains

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    Almir G. Wanderley

    2012-05-01

    Full Text Available 1,2,3-Triazoles have been extensively studied as compounds possessing important biological activities. In this work, we describe the synthesis of ten 2-(1-aryl-1<em>H>-1,2,3-triazol-4-ylpropan-2-ols via copper catalyzed azide alkyne cycloaddition (CuAAc or <em>click chemistryem>. Next the<em> in vitroem> antifungal activity of these ten compounds was evaluated using the microdilution broth method against 42 isolates of four different <em>Candida> species. Among all tested compounds, the halogen substituted triazole 2-[1-(4-chlorophenyl-1<em>H>-(1,2,3triazol-4-yl]propan-2-ol, revealed the best antifungal profile, showing that further modifications could be done in the structure to obtain a better drug candidate in the future.

  14. Extraction of Dihydroquercetin<em> em>from <em>Larix gmeliniem>i> em>with Ultrasound-Assisted and Microwave-Assisted Alternant Digestion

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    Yuangang Zu

    2012-07-01

    Full Text Available An ultrasound and microwave assisted alternant extraction method (UMAE was applied for extracting dihydroquercetin (DHQ from <em>Larix gmeliniem>i> wood. This investigation was conducted using 60% ethanol as solvent, 1:12 solid to liquid ratio, and 3 h soaking time. The optimum treatment time was ultrasound 40 min, microwave 20 min, respectively, and the extraction was performed once. Under the optimized conditions, satisfactory extraction yield of the target analyte was obtained. Relative to ultrasound-assisted or microwave-assisted method, the proposed approach provides higher extraction yield. The effect of DHQ of different concentrations and synthetic antioxidants on oxidative stability in soy bean oil stored for 20 days at different temperatures (25 °C and 60 °C was compared. DHQ was more effective in restraining soy bean oil oxidation, and a dose-response relationship was observed. The antioxidant activity of DHQ was a little stronger than that of BHA and BHT. Soy bean oil supplemented with 0.08 mg/g DHQ exhibited favorable antioxidant effects and is preferable for effectively avoiding oxidation. The <em>L. gmeliniiem> wood samples before and after extraction were characterized by scanning electron microscopy. The results showed that the UMAE method is a simple and efficient technique for sample preparation.

  15. Conhecimento e interesse em economia

    Directory of Open Access Journals (Sweden)

    João Antonio de Paula

    2003-09-01

    Full Text Available O artigo argumenta em favor da necessidade de preservar o pluralismo em economia. Discute: i a natureza do conhecimento e de sua produção; ii as especificidades da produção do conhecimento em economia e os condicionamentos histórico-culturais do conhecimento; iii as implicações da hegemonia de certa concepção de método em economia.The article argues the need to preserve the pluralism in economics. The article examines: i the nature of the knowledge and of its production; ii the specificity of the knowledge production in economics and the historical and cultural conditionings of the knowledge; iii the implications of the hegemony of a certain methodological conception in economics.

  16. Anti-jamming scheme of pilot modification MLD based on superimposed spread spectrum for UAV-MIMO%基于叠加扩频的无人机 MIMO 导频修正 MLD 抗干扰

    Institute of Scientific and Technical Information of China (English)

    陈自力; 高喜俊

    2015-01-01

    The remote control link of unmanned aerial vehicle (UAV)is often cluttered by interference, which results in performance degradation or losing lock.The technologies of multiple input multiple output (MIMO)space time block codes and direct spread are combined to suppress the common interference in the re-mote control link.The superimposed spread spectrum is presented to eliminate multiple access interference in the fusion technology,combat against narrow-band jamming and avoid deception jamming.The maximum likeli-hood decoding (MLD)based on the subspace projection of noise is adopted to suppress the noise interference of natural and strong wideband.The disturb deviation of MLD caused by channel estimation deviation is analyzed. Then the pilot modification is set up to reduce the effect of channel estimate error on MLD performance.The theoretical analysis and system simulation show that the scheme has better communication privacy and great ro-bustness which can suppress multi-population interferences.It can provide a scheme for achieving the intelligent anti-jamming of UAV in the future.%针对无人机遥控链路常受干扰的影响导致性能下降甚至失锁,研究将多输入多输出(multiple input multiple output,MIMO)空时分组编码与直扩技术相结合实现对链路常见干扰抑制。提出叠加扩频的方法消除融合技术中存在的多址干扰、对抗窄带干扰并预防欺骗干扰;采用基于噪声子空间投影的简化最大似然译码(maximum likelihood decoding,MLD)抑制自然以及强宽带噪声干扰,通过分析由信道估计误差引起的 MLD 扰动误差,并利用导频修正来降低信道估计误差对 MLD 性能影响。理论分析及仿真表明,该方案通信保密性好、鲁棒性强,能够实现对多种干扰的抑制,为未来无人机智能抗干扰的实现提供方案。

  17. Induction Coilgun for EM Mortar

    Science.gov (United States)

    2007-06-01

    Agency is investigating electromagnetic (EM) guns for the next generation combat vehicle providing improved performance and survivability without the...use of propellant. The two-year program was initiated in 2005 to design a coilgun and a railgun to launch an existing mortar round with an EM...through a structural frame. Capacitor bank modules currently in fabrication and test utilize 1980’s technology capacitors , but new ideas in

  18. Chemical Composition<em> em>of Hexane Extract of <em>Citrus aurantifoliaem> and<em> em>Anti->Mycobacterium tuberculosisem> Activity of Some of Its Constituents

    Directory of Open Access Journals (Sweden)

    María del Rayo Camacho-Corona

    2012-09-01

    Full Text Available The main aim of this study was to isolate and characterize the active compounds from the hexane extract of the fruit peels of <em>Citrus aurantiifoliaem>, which showed activity against one sensitive and three monoresistant (isoniazid, streptomycin or ethambutol strains of <em>Mycobacterium tuberculosis em>H37Rv. The active extract was fractionated by column chromatography, yielding the following major compounds: 5-geranyloxypsoralen (1; 5-geranyloxy-7-methoxycoumarin (2; 5,7-dimethoxycoumarin (3; 5-methoxypsoralen (4; and 5,8-dimethoxypsoralen (5. The structures of these compounds were elucidated by 1D and 2D NMR spectroscopy. In addition, GC-MS analysis of the hexane extract allowed the identification of 44 volatile compounds, being 5,7-dimethoxycoumarin (15.79%, 3-methyl-1,2-cyclopentanedione (8.27%, 1-methoxy-ciclohexene (8.0%, corylone (6.93%, palmitic acid (6.89%, 5,8-dimethoxypsoralen (6.08%, a-terpineol (5.97%, and umbelliferone (4.36%, the major constituents. Four isolated coumarins and 16 commercial compounds identified by GC-MS were tested against <em>M. tuberculosisem> H37Rv and three multidrug-resistant <em>M. tuberculosisem> strains using the Microplate Alamar Blue Assay. The constituents that showed activity against all strains were 5 (MICs = 25–50 mg/mL, 1 (MICs = 50–100 mg/mL, palmitic acid (MICs = 25–50 mg/mL, linoleic acid (MICs = 50–100 mg/mL, oleic acid (MICs = 100 mg/mL, 4-hexen-3-one (MICs = 50–100 mg/mL, and citral (MICs = 50–100 mg/mL. Compound 5 and palmitic acid were the most active ones. The antimycobacterial activity of the hexane extract of <em>C. aurantifoliaem> could be attributed to these compounds.

  19. Two New Compounds Isolated from<em> Liriope muscariem>

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    Rui-Chao Lin

    2012-07-01

    Full Text Available Two new compounds, (2<em>S>,3<em>R>-methyl 7-hydroxy-2-(4-hydroxy-3-methoxy-phenyl-3-(hydroxymethyl-2,3-dihydrobenzofuran-5-carboxylate (1 and (4<em>R,>5<em>S>-5-(3-hydroxy-2,6-dimethylphenyl-4-isopropyldihydrofuran-2-one (2, tentatively named norcurlignan and limlactone, respectively, were isolated from <em>Liriope muscariem>, together with the known compound (−-pinoresinol (3. The structures of these compounds were elucidated and characterized on the basis of 1D NMR, 2D NMR, CD and MS data. The <em>in vitroem> antioxidant activities of compounds 13 were assessed by the DPPH and ABTS scavenging methods.

  20. Antioxidant Activity of Various Parts of <em>Cinnamomum> cassiaem> Extracted with Different Extraction Methods

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    Li-Yeh Chuang

    2012-06-01

    Full Text Available The aim of this study was to investigate the antioxidant activities of various parts (barks, buds, and leaves of <em>Cinnamomum cassia em>extracted with ethanol and supercritical fluid extraction (SFE. For the antioxidant activity comparison, IC50 values of the SFE and ethanol extracts in the DPPH scavenging assay were 0.562–10.090 mg/mL and 0.072–0.208 mg/mL, and the Trolox equivalent antioxidant capacity (TEAC values were 6.789–58.335 mmole Trolox/g and 133.039–335.779 mmole Trolox/g, respectively. In addition, the total flavonoid contents were 0.031–1.916 g/ 100 g dry weight of materials (DW and 2.030–3.348 g/ 100 g DW, and the total phenolic contents were 0.151–2.018 g/ 100 g DW and 6.313–9.534 g/ 100 g DW in the SFE and ethanol extracts, respectively. Based on the results, the ethanol extracts of <em>Cinnamon> barks have potential value as an antioxidant substitute and this study also provide a better technique to extract the natural antioxidant substances from <em>C. cassiaem>.

  1. Regional Suppression of <em>Bactrocera> Fruit Flies (Diptera: Tephritidae in the Pacific through Biological Control and Prospects for Future Introductions into Other Areas of the World

    Directory of Open Access Journals (Sweden)

    Roger I. Vargas

    2012-08-01

    Full Text Available <em>Bactrocera> fruit fly species are economically important throughout the Pacific. The USDA, ARS U.S. Pacific Basin Agricultural Research Center has been a world leader in promoting biological control of <em>Bactrocera> spp. that includes classical, augmentative, conservation and IPM approaches. In Hawaii, establishment of <em>Bactrocera> <em>cucurbitae> (Coquillett in 1895 resulted in the introduction of the most successful parasitoid, <em>Psyttalia> <em>fletcheri> (Silvestri; similarly, establishment of <em>Bactrocera> <em>dorsalis> (Hendel in 1945 resulted in the introduction of 32 natural enemies of which <em>Fopius> <em>arisanus> (Sonan, <em>Diachasmimorpha> <em>longicaudata> (Ashmead and <em>Fopius> <em>vandenboschi> (Fullaway were most successful. Hawaii has also been a source of parasitoids for fruit fly control throughout the Pacific region including Australia, Pacific Island Nations, Central and South America, not only for <em>Bactrocera> spp. but also for <em>Ceratitis> and <em>Anastrepha> spp. Most recently, in 2002, <em>F.> <em>arisanus> was introduced into French Polynesia where <em>B.> <em>dorsalis> had invaded in 1996. Establishment of <em>D.> <em>longicaudata> into the new world has been important to augmentative biological control releases against <em>Anastrepha> spp. With the rapid expansion of airline travel and global trade there has been an alarming spread of <em>Bactrocera> spp. into new areas of the world (<em>i.e.>, South America and Africa. Results of studies in Hawaii and French Polynesia, support parasitoid introductions into South America and Africa, where <em>B.> <em>carambolae> and <em>B.> <em>invadens>, respectively, have become established. In addition, <em>P.> <em>fletcheri> is a candidate for biological control of <em>B.> <em>cucurbitae> in Africa. We review past and more

  2. CATETERES EM TERAPIA INTENSIVA

    Directory of Open Access Journals (Sweden)

    Carolina de Deus Lisboa

    2014-01-01

    Full Text Available Pesquisa com os objetivos de identificar falhas na administração de medicamentos por sondas e caracterizar a interrupção ou não da nutrição no caso de medicamentos que exigem jejum relativo. Estudo epidemiológico, transversal, observacional, numa terapia intensiva, com amostra de 350 doses administradas por 56 técnicos de enfermagem. Resultados mostraram que não houve pausa entre a administração do medicamento e a infusão de dieta enteral em 116 (33,14% doses de medicamentos que necessitavam de jejum relativo, entre os quais captopril, varfarina sódica, levotiroxina sódica, digoxina e fenitoína sódica. A irrigação das sondas não ocorreu na maioria dos casos (94,28%. Conclui-se que é possível que os medicamentos citados tenham tido sua biodisponibilidade sérica reduzida, comprometendo sua eficácia terapêutica e que a falta da prática de irrigar sondas com água estéril, antes de administrar medicamentos, configura-se como a ausência de um cuidado específico fundamental para evitar a obstrução das mesmas.

  3. <em>Neoromicia> Roberts, 1926 (Mammalia Vespertilionidae: correction of gender and etymology

    Directory of Open Access Journals (Sweden)

    Marco Riccucci

    2009-02-01

    Full Text Available Riassunto <em>Neoromicia> Roberts, 1926 (Mammalia, Verspetilionidae: Correzione del genere grammaticale ed etimologia <em>Neoromicia> Roberts, 1926, sinora considerato erroneamente di genere maschile, è in realtà femminile. La sua etimologia deriva quasi certamente dal Greco antico "ρóμιζα", corrispondente al latino "<em>Rumex>" (sorta di giavellotto, per la presenza di un cospicuo sperone calcaneale in <em>Romicia calcarataem>, specie tipo del genere.

  4. Activity-Guided Isolation of Antioxidant Compounds from <em>Rhizophora apiculataem>

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    Hongbin Xiao

    2012-09-01

    Full Text Available <em>Rhizophora apiculataem> (<em>R. apiculataem> contains an abundance of biologically active compounds due its special salt-tolerant living surroundings. In this study, the total phenolic content and antioxidant activities of various extract and fractions of stem of <em>R. apiculataem> were investigated. Results indicated that butanol fraction possesses the highest total phenolic content (181.84 mg/g GAE/g dry extract with strongest antioxidant abilities. Following <em>in vitroem> antioxidant activity-guided phytochemical separation procedures, lyoniresinol-3α-<em>O>-β-arabinopyranoside (1, lyoniresinol-3α-<em>O>-β-rhamnoside (2, and afzelechin-3-<em>O>-L-rhamno-pyranoside (3 were separated from the butanol fraction. These compounds showed more noticeable antioxidant activity than a BHT standard in the DPPH, ABTS and hydroxyl radical scavenging assays. HPLC analysis results showed that among different plant parts, the highest content of 13 was located in the bark (0.068%, 0.066% and 0.011%, respectively. The results imply that the <em>R. apiculataem> might be a potential source of natural antioxidants and 13 are antioxidant ingredients in <em>R. apiculataem>.

  5. Busca de estruturas em grandes escalas em altos redshifts

    Science.gov (United States)

    Boris, N. V.; Sodrã©, L., Jr.; Cypriano, E.

    2003-08-01

    A busca por estruturas em grandes escalas (aglomerados de galáxias, por exemplo) é um ativo tópico de pesquisas hoje em dia, pois a detecção de um único aglomerado em altos redshifts pode por vínculos fortes sobre os modelos cosmológicos. Neste projeto estamos fazendo uma busca de estruturas distantes em campos contendo pares de quasares próximos entre si em z Â3 0.9. Os pares de quasares foram extraídos do catálogo de Véron-Cetty & Véron (2001) e estão sendo observados com os telescópios: 2,2m da University of Hawaii (UH), 2,5m do Observatório de Las Campanas e com o GEMINI. Apresentamos aqui a análise preliminar de um par de quasares observado nos filtros i'(7800 Å) e z'(9500 Å) com o GEMINI. A cor (i'-z') mostrou-se útil para detectar objetos "early-type" em redshifts menores que 1.1. No estudo do par 131046+0006/J131055+0008, com redshift ~ 0.9, o uso deste método possibilitou a detecção de sete objetos candidatos a galáxias "early-type". Num mapa da distribuição projetada dos objetos para 22 < i' < 25 observou-se que estas galáxias estão localizadas próximas a um dos quasares e há indícios de que estejam aglomeradas dentro de um área de ~ 6 arcmin2. Se esse for o caso, estes objetos seriam membros de uma estrutura em grande escala. Um outro argumento em favor dessa hipótese é que eles obedecem uma relação do tipo Kormendy (raio equivalente X brilho superficial dentro desse raio), como a apresentada pelas galáxias elípticas em z = 0.

  6. Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine <em>Ostreae em>concha>

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    Hong-Bing Liu

    2012-05-01

    Full Text Available To compare the chemical differences between the medicinal and<em> em>cultured oyster shells, their chemical profiles were investigated. Using the ultra performance liquid chromatography-electron spraying ionization-mass spectrometry (UPLC-ESI-MS, combined with principal component analysis (PCA and orthogonal projection to latent structures discriminant analysis (OPLS-DA, the discrimination of the chemical characteristics among the medicinal and cultured oyster shells was established. Moreover, the chemometric analysis revealed some potential key compounds. After a large-scale extraction and isolation, one target key compound was unambiguously identified as caffeine (1 based on extensive spectroscopic data analysis (1D and 2D NMR, MS, and UV and comparison with literature data.

  7. Tratamento da dor em queimados

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    Rodrigo José Alencar de Castro

    2013-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Apesar dos avanços, ainda é observado manejo analgésico inadequado dos pacientes com queimaduras. O objetivo desta revisão foi coletar dados sobre tratamento da dor em queimados. CONTEÚDO: Foi feita revisão sobre os mecanismos de dor, avaliação do paciente com queimadura e o tratamento farmacológico e não farmacológico. CONCLUSÕES: O manejo da dor em pacientes vítimas de queimaduras ainda é um desafio por parte da equipe multiprofissional. A avaliação frequente e contínua da resposta apresentada pelo paciente é muito importante, tendo em vista os vários momentos por que passa o paciente internado em decorrência de uma queimadura, além de uma terapêutica combinada com medicações analgésicas e medidas não farmacológicas. Entender a complexidade de alterações fisiopatológicas, psicológicas e bioquímicas apresentadas por um paciente em tratamento de queimadura é o primeiro passo para alcançar o sucesso no seu manejo analgésico.

  8. A case of phaeohyphomycosis caused by Exophiala spinifera superimposed on basal cell carcinoma%基底细胞上皮瘤伴棘状外瓶霉所致的暗色丝孢霉病一例

    Institute of Scientific and Technical Information of China (English)

    林能兴; 郑岳臣; 曾敬思; 黄长征; 连昕; 毛叶红; 黄春艳

    2010-01-01

    A 67-year-old female farmer presented with a painless dark-erythematous, green bean-sized nodule on the left side of her head for 5 years.The nodule gradually grew and extended to the left temple.Three months prior to the presentation, the lesion began to enlarge rapidly and ulcerate.Histopathology of the lesion revealed a diagnosis of basal cell carcinoma.Brown hypha, spores, and blastospores were observed between cancer cell nests and in necrotic tissues.Culture of biopsy materials grew moist, glistening, olivaceous-black or dark yeast-like colonies, with gray fluffy hyphae at the margin.Slide culture showed brown branched and septate hypha, with spinate conidiophores arising terminally or laterally at right angles.There were rhino-protuberances at the tip of conidiophores together with clumps of smooth, oval microconidia at the top of or around the conidiophores, and many clear annellations were observed at the distant end of conidiophores.The strain was identified as Exophiala spinifera and confirmed genetically.The patient was diagnosed as phaeohyphomycosis caused by Exophiala spinifera superimposed on basal cell carcinoma based on the clinical manifestations,histopathological and mycological examinations, as well as DNA sequencing results.Clinical cure was achieved after management with oral itraconazole and 10-session photodynamic therapy.No recurrence was noted during 1-year follow-up.%患者女,67岁,农民.5年前左头顶部长出一无痛性绿豆大小暗红色结节,逐年扩大、隆起,并延及左颞部.近3个月结节、肿块迅速增大,并出现溃疡.肿块经组织病理检查,诊断为基底细胞上皮瘤,肿瘤细胞巢之间和坏死组织内有褐色菌丝、孢子、芽生孢子.真菌培养为深橄榄黑色酵母样菌落,潮湿有光泽,边缘一圈灰色短绒毛状菌丝.方块小培养镜下见褐色分支分隔菌丝,其顶端与侧缘有成直角长出的棘状分生孢子梗,梗尖端有鼻状突起,顶尖及其周围有成

  9. Botulismo tipo C em perus em Minas Gerais, Brasil

    OpenAIRE

    Lobato,Francisco Carlos Faria; Salvarani,Felipe Masiero; Silva,Rodrigo Otávio Silveira; Assis,Ronnie Antunes de; Lago,Luis Alberto do; Carvalho Filho,Maurício Baltazar de; Martins,Nelson Rodrigo da Silva

    2009-01-01

    O botulismo é uma intoxicação causada pela ingestão das toxinas produzidas pelo Clostridium botulinum, que acomete mamíferos e aves e é caracterizado por um quadro de paralisia flácida. Neste trabalho, é descrito um surto de botulismo em perus, ocorrido no município de Santa Luzia, região metropolitana de Belo Horizonte, Minas Gerais. Os animais apresentavam incoordenação motora, paralisia flácida das patas, asas e pescoço. Em um intervalo de 24 horas, todos os 29 animais do plantel vieram a ...

  10. Narcisismo e corporeidade em Freud

    OpenAIRE

    Gaio, Fernando Moysés

    2015-01-01

    A indagação deste estudo parte da constatação de que Freud atribui uma origem narcísica ao eu, e, ao mesmo tempo, refere-se ao eu como um eu corporal. Essa afirmação coloca em questão a relação do narcisismo com a corporeidade, que não é explicitamente tematizada em sua obra, aparecendo sempre de forma dispersa ao longo de seu desenvolvimento. As referências a respeito do tema do narcisismo em suas obras revelam, além disso, uma contínua evolução do seu conceito. Neste estudo, acompanha-se pr...

  11. Divisão de trabalho em cuidados à prole em Sicalis flaveola (Linnaeus, 1766) (Passeriformes, Emberizidae), em cativeiro

    OpenAIRE

    Luiz Octavio Marcondes-Machado

    1988-01-01

    São relatadas observações relativas à divisão de trabalho em cuidados à prole em Sicalis flaveola brasiliensis (Gmelin) e S. f. pelzelni (Sclater), em condições de cativeiro.Observations relating to the division of labour for young care in Sicalis flaveola brasiliensis (Gmelin) and S. f. pelzelni (Sclater), in captivity, are presented.

  12. Objetos mediadores em museus

    Directory of Open Access Journals (Sweden)

    Inês Ferreira

    2015-02-01

    Full Text Available Um museu participativo incentiva a que a experiência da visita seja criativa e pessoal. Facilita a participação biográfica do visitante - com a sua experiência, conhecimento e interesses. Muitas exposições, porém, não promovem esse envolvimento pessoal. Neste artigo apresentamos uma revisão da literatura que indicia que a mediação com objetos mediadores facilita o envolvimento pessoal, a construção de conhecimento e a criatividade. O problema teórico que colocamos é se os museus mais tradicionais se podem abrir à participação e, neste contexto, o nosso objetivo é perceber que papel podem ter os objetos mediadores nesse processo. Discutimos o recurso a objetos mediadores como forma de adicionar múltiplos níveis de relação e modos de ver, potencial que consideramos subaproveitado em muitos museus. Começamos por apresentar o museu como espaço potencialmente participativo, que convida a um envolvimento ativo e crítico – ativo, porque o visitante é desafiado a fazer coisas; crítico, porque é estimulado a pensar, optar, discutir e refletir. Discutimos depois diferentes formas de usar objetos mediadores para incentivar o visitante a um envolvimento com os artefactos, recorrendo à memória, experiência, conhecimento e sentimentos. A participação biográfica potencia o cruzamento entre o mundo interior do visitante e os artefactos e conteúdos do museu. Esse espaço de cruzamento - inbetween - é o espaço da construção de conhecimento. Apresentamos diversas formas de um museu, mesmo não sendo interativo, se tornar mais criativo e participativo, o que pode contribuir para uma mudança nas práticas dos museus, nomeadamente na montagem e remodelação de exposições permanentes.

  13. Formamido-Diterpenes from the South China Sea Sponge <em>Acanthella cavernosaem>

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    Bao-Hua Zhang

    2012-07-01

    Full Text Available Seven new formamido-diterpenes, cavernenes A–D (14, kalihinenes E and F (56, and kalihipyran C (7, together with five known compounds (812, were isolated from the South China Sea sponge <em>Acanthella cavernosaem>. Structures were established using IR, HRESIMS, 1D and 2D NMR, and single X-ray diffraction techniques. The isolated compounds were assessed for their cytotoxicity against a small panel of human cancer cell lines (HCT-116, A549, HeLa, QGY-7701, and MDA-MB-231 with IC50 values in the range of 6–18 μM. In addition, compound 9 showed weak antifungal activity against <em>Trichophyton rubrumem> and <em>Microsporum gypseumem> with MIC values of 8 and 32 μg/mL, respectively, compound 10 displayed weak antifungal activity against fungi <em>Candida albicansem>, <em>C>ryptococcus neoformansem>, <em>T. rubrumem>, and<em> M. gypseum em>with MIC values of 8, 8, 4, and 8 μg/mL, respectively.

  14. Cluster de ventiladores em Catanduva.

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    Luciana M. Onusic

    2005-04-01

    Full Text Available Este trabalho apresenta os resultados de um levantamento feito na cidade de Catanduva sobre a indústria de ventiladores nela instalada. É, inicialmente, apresentado o conceito de cluster, para, em seguida, serem apresentadas as características do setor de ventiladores de Catanduva, fazendo uma comparação desse setor com o conceito de cluster. Diversos aspectos mostram o interesse em considerar o setor como um cluster e são feitas sugestões para seu aprimoramento.

  15. Hiperplasia gengival medicamentosa em Odontopediatria

    OpenAIRE

    Lourenço, Lília Carla Carvalho

    2013-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária Um periodonto saudável com os seus constituintes é uma parte fundamental para uma boa saúde oral em qualquer género e idade. As crianças também são afetadas por patologias periodontais, nomeadamente a hiperplasia gengival; esta pode ser de variados tipos e etiologias, sendo um desses tipos a hiperplasia gengival medicamentosa (HGM) p...

  16. Alegoria redimida em Walter Benjamin

    OpenAIRE

    Anderson Borges

    2012-01-01

    Este estudo apresenta o decurso da alegoria na obra benjaminiana circunscrevendo a investigação a três momentos principais: o livro Origem do drama barroco alemão, em que a alegoria é resgatada do esquecimento e, considerando a significativa expressividade do luto (Trauer) e da melancolia na constituição do teatro barroco, ganha um lugar cativo no âmbito estético, bem como, além disso, funciona como representação da história na perspectiva de literatos do século XVII; Rua de mão única, em que...

  17. Treino cognitivo em idosos institucionalizados

    OpenAIRE

    Ferreira, Sara Melissa

    2012-01-01

    Face ao crescimento e longevidade da população idosa na sociedade atual torna-se cada vez mais necessário criar estratégias em prol de um Envelhecimento Ativo, ambicionando mais qualidade nos anos vividos. Sabe-se que ao longo do desenvolvimento humano existem perdas e ganhos. Estudos documentam declínio da capacidade da memória em indivíduos de idade avançada. No entanto, existem inúmeras evidências científicas da plasticidade cerebral que fundamentam a intervenção cognitiva através de Progr...

  18. Adaptabilidade e estabilidade em aveia em ambientes estratificados

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    Bertan Ivandro

    2005-01-01

    Full Text Available Vinte cultivares de aveia (Avena sativa L. foram avaliados para rendimento de grãos nas safras agrícolas de 2001 e 2002 em nove locais dos estados do Paraná, Rio Grande do Sul e São Paulo, com o objetivo de avaliar as estimativas dos componentes de adaptabilidade e estabilidade do rendimento de grãos em ambientes favoráveis e desfavoráveis em presença e ausência de aplicação de fungicida. Foi empregada a metodologia de EBERHART & RUSSELL (1966. A presença de significância para anos, genótipos, fungicidas e locais, indicou comportamento diferencial de genótipos frente às variações de ambiente e a aplicação de fungicida, nas condições de ambientes favoráveis e desfavoráveis. A aplicação de fungicida e o favorecimento do ambiente de cultivo afetaram intensamente os parâmetros de adaptabilidade (b1 e estabilidade (s²d i, indicando que estas estimativas devam ser realizadas em ambientes estratificados, apesar de nenhuma constituição genética ter evidenciado o biótipo ideal, conforme preconizado pelo modelo adotado.

  19. Low Diversity Bacterial Community and the Trapping Activity of Metabolites from Cultivable Bacteria Species in the Female Reproductive System of the Oriental Fruit Fly, <em>Bactrocera dorsalisem> Hendel (Diptera: Tephritidae

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    Hongyu Zhang

    2012-05-01

    Full Text Available Our goal was to identify the bacteria inhabiting the reproductive system of the female oriental fruit fly, <em>Bactrocera dorsalisem> (Hendel, and evaluate the chemotaxis of <em>B>. <em>dorsalis> to the metabolites produced by the bacteria. Based on 16S rRNA-based polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE, 18 operational taxonomic units (OTUs were assigned to the five bacterial classes <em>Betaproteobacteria>, <em>Alphaproteobacteria>, <em>Gammaproteobacteria>, <em>Bacilli> and <em>Actinobacteria>. Nine OTUs were assigned to <em>Gammaproteobacteria>, which was the most highly represented class. <em>Enterobacteriaceae> constituted the dominant family, and within this family, three genera and five species were identified, including <em>Enterobacter sakazakiiem>, <em>Klebsiella> <em>oxytoca>, <em>Klebsiella> <em>pneumoniae,> Raoultellaem> <em>terrigena em>and <em>Enterobacter> <em>amnigenus>. In this set, the first two species were the dominant components, and the latter three species were the minor ones. Finally, we found that the metabolites produced by <em>R.> terrigenaem>, <em>K. oxytocaem> and <em>K.> pneumoniae em>were attractive to the <em>B.> dorsalisem> adults, and in field studies, <em>B.> dorsalisem> adults were most attracted to <em>K.> oxytocaem>. Collectively, our results suggest that the female reproductive system plays an important role in the transfer of enterobacteria from the gut to fruit. Our data may prompt the development of a female-targeted population control strategy for this fly.

  20. Effects of Two Varieties of <em>Bacillus thuringiensisem> Maize on the Biology of <em>Plodia interpunctellaem>

    Directory of Open Access Journals (Sweden)

    Jean-Claude Grégoire

    2012-05-01

    Full Text Available On the market since 1996, genetically modified plants expressing an insecticidal toxin (Cry toxin stemmed from <em>Bacillus thuringiensisem> target several lepidopteran and coleopteran pests. In this study, we assessed the impact of two varieties of <em>Bt em>maize producing different toxins (Cry1Ab or Cry1Fa, respectively on the biology of a storage pest: <em>Plodia interpunctella em>(Hübner (Lepidoptera: Pyralidae. The Indianmeal moths were susceptible to both toxins but showed an escape behavior only from Cry1Fa. The weight of females issued from larvae reared on Cry1Ab increased with increasing toxin concentration, but adults of both sexes reared on Cry1Fa had decreased weight. Both toxins increased development time from egg to adult regardless of sex and had no impact on the male adult lifespan. Finally, we recorded a time lag between metamorphosis from the non-<em>Bt em>and the <em>Bt em>diets, which increased proportionally to Cry concentration in the <em>Bt em>diet.

  1. A Novel Apoptosis Correlated Molecule: Expression and Characterization of Protein Latcripin-1 from <em>Lentinula em>edodes> C91–3

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    Min Huang

    2012-05-01

    Full Text Available An apoptosis correlated molecule—protein Latcripin-1 of <em>Lentinula> edodesem> C91-3—was expressed and characterized in <em>Pichia pastorisem> GS115. The total RNA was obtained from <em>Lentinula edodesem> C91–3. According to the transcriptome, the full-length gene of Latcripin-1 was isolated with 3'-Full Rapid Amplification of cDNA Ends (RACE and 5'-Full RACE methods. The full-length gene was inserted into the secretory expression vector pPIC9K. The protein Latcripin-1 was expressed in <em>Pichia pastorisem> GS115 and analyzed by Sodium Dodecylsulfonate Polyacrylate Gel Electrophoresis (SDS-PAGE and Western blot. The Western blot showed that the protein was expressed successfully. The biological function of protein Latcripin-1 on A549 cells was studied with flow cytometry and the 3-(4,5-Dimethylthiazol-2-yl-2,5-Diphenyl-tetrazolium Bromide (MTT method. The toxic effect of protein Latcripin-1 was detected with the MTT method by co-culturing the characterized protein with chick embryo fibroblasts. The MTT assay results showed that there was a great difference between protein Latcripin-1 groups and the control group (<em>p em>< 0.05. There was no toxic effect of the characterized protein on chick embryo fibroblasts. The flow cytometry showed that there was a significant difference between the protein groups of interest and the control group according to apoptosis function (<em>p em>< 0.05. At the same time, cell ultrastructure observed by transmission electron microscopy supported the results of flow cytometry. The work demonstrates that protein Latcripin-1 can induce apoptosis of human lung cancer cells A549 and brings new insights into and advantages to finding anti-tumor proteins.

  2. Antifungal Activity, Toxicity and Chemical Composition of the Essential Oil of <em>Coriandrum sativumem> L. Fruits

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    Erika H. S. Brito

    2012-07-01

    Full Text Available The aims of this study were to test the antifungal activity, toxicity and chemical composition of essential oil from <em>C. sativumem> L. fruits. The essential oil, obtained by hydro-distillation, was analyzed by gas chromatography/mass spectroscopy. Linalool was the main constituent (58.22%. The oil was considered bioactive, showing an LC50 value of 23 µg/mL in the <em>Artemia salinaem> lethality test. The antifungal activity was evaluated against <em>Microsporum canisem> and <em>Candida> spp. by the agar-well diffusion method and the minimum inhibitory concentration (MIC and the minimum fungicidal concentration (MFC were established by the broth microdilution method. The essential oil induced growth inhibition zones of 28 ± 5.42 and 9.25 ± 0.5 for <em>M. canisem> and <em>Candida> spp. respectively. The MICs and MFCs for <em>M. canisem> strains ranged from 78 to 620 and 150 to 1,250 µg/mL, and the MICs and MFCs for <em>Candida> spp strains ranged from 310 to 620 and 620 to 1,250 µg/mL, respectively. <em>C. sativumem> essential oil is active<em> in vitroem> against <em>M. canis em>and> Candidaem> spp. demonstrating good antifungal activity.

  3. Rodent hosts of <em>Maritrema> sp. (Digenea, Microphallidae in Sardinia Island

    Directory of Open Access Journals (Sweden)

    Juan Carlos Casanova

    2003-10-01

    Full Text Available Prospections on helminth fauna of rodents were carried out in the Cedrino river (Eastern of Sardinia island. Twelve <em>Rattus rattusem> (L., 1758 and eight <em>Mus domesticusem> (Schwarz & Schwarz, 1943 were captured by Sherman traps. Parasitological study revealed in <em>R. rattusem> the presence of an intestinal helminth belonging to the genus <em>Maritrema> (family Microphallidae. The transmission of this Digenetic Trematode among vertebrates involves the participation of aquatic invertebrate organisms, molluscs and crustacea, acting as intermediate hosts. Dissection of 117 individuals of the Amphipod Crustacea <em>Gammarus italicusem>, collected in the same biotope, allowed the detection of encysted metacercariae. These larvae constitute the infesting stage of the parasite for vertebrates, acting these as definitive hosts ingesting parasitized crustacea as preys. Adults of <em>Maritrema> sp. were also obtained experimentally in the laboratory mice (<em>Mus domesticusem> CD1 strain. These were infested by inoculating them, using gastric probe, metacercarial cysts isolated from <em>G. italicusem>. Post-infection mice dissection was performed at different intervals of time getting adults in various maturity stages. Experimental facts confirm that <em>Maritrema> sp., as it occurs in other trematodes, do not present strict specificity to the definitive host, being able to develop as well in <em>Mus>. In nature, the presence or absence of this digenean in mammals species will be dependent of host ethological factors, mainly related to feeding habitats. This study was partially supported by the ?Comissionat per Recerca i Universitats de la Generalitat de Catalunya? 2001SGR00088.

  4. Análise da transformada em ondeletas aplicada em sinal geofísico

    OpenAIRE

    Bolzan,Maurício José Alves

    2004-01-01

    É mostrada uma análise em ondeletas aplicada em um sinal geofísico, número de manchas solares. Para isso, é dado uma introdução teórica sobre a Transformada em Ondeletas e sobre séries e Transformada de Fourier. A Transformada em Ondeletas é uma ferramenta matemática de grande utilidade aplicação em sinais não-estacionários.

  5. Unusual Burn as a Complication of Paraplegia Treatment Caused by an Electrotherapy Device

    OpenAIRE

    Celalettin Sever

    2011-01-01

    Electromyostimulation (EMS) therapy is widely used as a part of physiotherapy for all patterns of skeletal muscle weaknesses like paresis, paralysis, neuropathies, and myopathies. To our knowledge, burns caused by the use of an electrotherapy device have not been reported earlier. We report the case of a 21-yearold man who suffered full thickness burns by electrical stimulation with electrode implanted on the anterior side of his left thigh. The burn area was treated consevatively within f...

  6. Contribution to the knowledge of <em>Apodemus> genus in the Gran Paradiso National Park

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    Paolo Debernardi

    2003-10-01

    Full Text Available Abstract Between 1992 and 2001, small mammals were trapped in the Gran Paradiso National Park (NW Italy, using Capture-Mark-Recapture techniques. According to a sample of data collected in August, the following percentages were found for the genus <em>Apodemus>: 25.9% of the individuals caught in alder shrubwoods, 20.9% in hardwoods, 12.1% in open habitat-types and 3.1% in coniferous woods. Further trapping, carried out in winter in the villages inside the Park, demonstrated that <em>Apodemus> occurrence inside the buildings was quite common. Fiftytwo specimens were sacrificed and identified by protein electrophoresis and/or molecular analyses as <em>A. alpicolaem> (N= 14, <em>A. flavicollisem> (N= 21 and <em>A. sylvaticusem> (N= 17. External morphology and biometric parameters were analysed on the above specimens, as were cranial features, and the effectiveness of the determination technique proposed by Reutter <em>et al.em> on the study area material was verified. This technique enabled us to determine other specimens (mainly from discarded bottles using skull analysis. <em>A. flavicollisem> (recorded from the lowest altitude of the area, 750 m, up to 2123 m a.s.l. dominated in hardwoods. <em>A. alpicolaem> (recorded from 1580 m to 2423 m is more abundant above 1750 m, in alder shrubwoods and in open habitat-types, characterized by patches of rocky elements, low ligneous and herbaceus vegetation. All the individuals caught inside buildings were <em>A. sylvaticusem>, but this species (recorded from 750 m to 1960 m was scarcely observed in natural habitats. <em>Strix alucoem> and <em>Aegolius funereusem> prey remains, collected in the area during the breeding period of both owls, were examined. <em>Apodemus> accounted for 13.7% of prey and 9.4% of biomass eaten by <em>Strix alucoem> and for 7.2% of prey and 7.3% of biomass consumed by <em>Aegolius funereusem>. Riassunto

  7. Allometric and Isometric variations in the Italian <em>Apodemus sylvaticusem> and <em>Apodemus flavicollisem> with respect to the conditions of allopatry and sympatry / Variazioni allometriche e isometriche in <em>Apodemus sylvaticusem> e <em>Apodemus flavicollisem> italiani, rispetto alle condizioni di allopatria e simpatria

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    Giovanni Amori

    1986-12-01

    Full Text Available Abstract In Italy there are two species of <em>Apodemus> (<em>Sylvaemus>: <em>Apodemus sylvaticusem> on the mainland and the main island, and <em>Apodemus flavicollisem> only on the mainland. The trend of some morphometric characters of the skull (incisive foramen length - FI; interorbital breadth = IO; length of palatal bridge = PP; upper alveolar length = $M^1M^3$ was analized and some theoretical models verified for <em>A. sylvaticusem>. If one considers the sympatric population of <em>A. sylvaticusem> and <em>A. flavicollisem> simultaneously the characters PP, IO and $M^1M^3$ appear significantly isometric being directly correlated ($P leq O.O1$, while FI character results allometric with respect to the previous ones, as expected. If one considers the sympatric populations of each of the species separately, the scenario is different. For <em>A. sylvaticusem> only PP and $M^1M^3$ are isometric ($P leq 0.05$. For <em>A. flavicollisem> only $M^1M^3$ and FI appear to be correlated, although not as significantly as for <em>A. sylvaticusem> ($P le 0.05$; one tail. The insular populations of <em>A. sylvaticusem> do not show significant correlations, except for FI and $M^1M^3$ ($P le 0.05$. On the contrary, considering all populations, sympatric and allopatric, of <em>A. sylvaticusem> at the same time are significant correlations ($P le 0.05$ in all combinations of characters, except for those involving the IO. We suggest that the isometric relations in sympatric assemblages are confined within a morphological range available to the genus <em>Apodemus>. In such a space, the two species are split in two different and innerly homogeneous distributions. We found no evidence to confirm the niche variation hypothesis. On the contrary, the variability expressed as SO or CV's appears higher in the sympatric populations than in the allopatric ones, for three of the four characters, confirming previous results

  8. Planejamento em Saúde

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    Antonio José Costa CARDOSO

    2014-03-01

    Full Text Available Esse texto pretendeu subsidiar aula sobre Planejamento e Avaliação em Saúde para os Analistas Técnicos de Políticas Sociais lotados no Ministério da Saúde (MS, na perspectiva de promover uma maior compreensão dos antecedentes históricos do planejamento em saúde no Brasil e na América Latina, do referencial teórico metodológico do planejamento estratégico e participativo, e refletir sobre os avanços e desafios que se apresentam no atual contexto de construção do Sistema Único de Saúde (SUS. Neste sentido, foi estruturado na perspectiva de responder a três questões orientadoras: 1 Como tem se dado esse processo de coordenação do Planejamento Estratégico Nacional no âmbito do SUS, em cooperação técnica com os Estados, Municípios e Distrito Federal? 2 Quais são as tecnologias de gestão e planejamento em saúde adotadas pelo MS para conduzir esses processos de forma integrada? 3 Como se dá o gerenciamento das ações no MS? Como os planos, projetos e programas são monitorados pelas equipes responsáveis?

  9. Action of Chitosan Against <em>Xanthomonas> Pathogenic Bacteria Isolated from <em>Euphorbia pulcherrimaem>

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    Yanli Wang

    2012-06-01

    Full Text Available The antibacterial activity and mechanism of two kinds of chitosan were investigated against twelve <em>Xanthomonas> strains recovered from <em>Euphorbia pulcherrimaem>. Results indicated that both chitosans markedly inhibited bacterial growth based on OD loss. Furthermore, the release of DNA and RNA from three selected strains was increased by both chitosans. However, the release of intracellular proteins was inhibited by both chitosans at different concentration and incubation times, except chitosan A at 0.1 mg/mL for 0.5 h incubation and 0.2 mg/mL for 2.0 h incubation increased the release of proteins, indicating the complexity of the interaction and cell membranes, which was affected by incubation time, bacterial species, chitosan type and concentration. Transmission electron microscopic observations revealed that chitosan caused changes in protoplast concentration and surface morphology. In some cells, the membranes and walls were badly distorted and disrupted, while other cells were enveloped by a thick and compact ribbon-like layer. The contrary influence on cell morphology may explain the differential effect in the release of material. In addition, scanning electron microscope and biofilm formation test revealed that both chitosans removed biofilm biomass. Overall, this study showed that membrane and biofilm play an important role in the antibacterial mechanism of chitosan.

  10. EMS wave logger data processing

    NARCIS (Netherlands)

    Verhagen, H.J.

    2013-01-01

    Waves can be measured in several ways. One way of measuring waves is by measuring the wave pressure at a certain depth using a pressure sensor and calculate the wave information from the pressure record. The EMS wave logger uses a Honeywell MLH 050 PGP 06A pressure sensor. The information is stored

  11. Synthesis and Characterization of Some New <em>C2em> Symmetric Chiral Bisamide Ligands Derived from Chiral Feist’s Acid

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    Assem Barakat

    2012-05-01

    Full Text Available The hemilabile chiral <em>C2em> symmetrical bidentate substituted amide ligands (1<em>R>,2<em>R>-5a-d and (1<em>S>,2<em>S>-6a-d were synthesized in quantitative yield from (1<em>R>,2<em>R>-(+-3-methylenecyclo-propane-1,2-dicarboxylic acid (1<em>R>,2<em>R>-3 and (1<em>S>,2<em>S>-(--3-methylene-cyclopropane-1,2-dicarboxylic acid (1<em>S>,2<em>S>-3, in two steps, respectively. The chiral Feist’s acids (1<em>R>,2<em>R>-3 and (1<em>S>,2<em>S>-3 were obtained in good isomeric purity by resolution of <em>trans>-(±-3-methylene-cyclopropane-1,2-dicarboxylic acid from an 8:2 mixture of <em>tert>-butanol and water, using (<em>R-(+-α>-methylbenzyl amine as a chiral reagent. This process is reproducible on a large scale. All these new synthesized chiral ligands were characterized by 1H-NMR, 13C-NMR, IR, and mass spectrometry, as well as elemental analysis and their specific rotations were measured. These new classes of <em>C2em> symmetric chiral bisamide ligands could be of special interest in asymmetric transformations.

  12. Parasitic zoonoses: survey in foxes (<em>Vulpes vulpesem> in the northern Apennines / Zoonosi parassitarie: indagini in volpi (<em>Vulpes vulpesem> dell'Appennino settentrionale

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    Vittorio Guberti

    1991-07-01

    Full Text Available Abstract A parasitological survey on 153 foxes was carried out in the northern Apennines, during the period 1984-1987. The following parasites were identified: <em>Toxocara canisem> (46.4%, <em>Taenia> sp. (17%, <em>Uncinaria stenocephalaem> (11.8%, <em>Mesocestoides lineatusem> (11.1%, <em>Ancylostoma caninumem> (3.9%, <em>Taenia hydatigenaem> (3.3%, <em>Trichuris vulpisem> (3.3%, <em>Dipylidium caninumem> (2.6%, <em>Taenia crassicepsem> (2%. All foxes were negative for <em>Trichinella> sp. A statistical analysis was performed to evaluate differences in the parasitic fauna according to the sex and age classes of the hosts. The role that the fox could have as a reservoir of helminthic zoonoses is discussed. The results are compared with those of similar studies carried out in Italy. Riassunto Nel periodo 1984-1987 è stata condotta un'indagine parassitologica su 153 volpi abbattute nell'Appennino romagnolo. Sono stati reperiti i seguenti parassiti: <em>Toxocara canisem> (46,4%, <em>Taenia> sp. (17%, <em>Uncinaria stenocephalaem> (11,8%, <em>Mesocestoides lineatusem> (11,1%, <em>Ancylostoma caninumem> (3,9%, <em>Taenia hydatigenaem> (3,3%, <em>Trichuris vulpisem> (3,3%, <em>Dipylidium caninumem> (2,6%, <em>Taenia crassicepsem> (2%. Tutte le volpi esaminate sono risultate negative per <em>Trichinella> sp. È stata effettuata l'analisi statistica dei dati per evidenziare eventuali differenze della fauna parassitaria in relazione al sesso e all'età delle volpi. Sulla base dei dati ottenuti viene discussa l'importanza che la Volpe può assumere come serbatoio di zoonosi elmintiche. I risultati acquisiti sono inoltre comparati con quelli ottenuti in analoghe ricerche condotte in Italia.

  13. First sign of <em>Clethrionomys glareolusem> in the Po valley plain / Prima segnalazione in Pianura Padana di <em>Clethrionomys glareolusem>

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    Luis Nieder

    1987-07-01

    Full Text Available Abstract The presence of <em>Clethrionomys glareolusem> (Schreber, 1790 populations is reported in the Po valley, formerly considered outside the distribution area of the species. An initial series of captures was made in the high-water area of the Po near S. Nazzaro (Monticelli d'Ongina - PC following with research was extended along the river's banks in Emilia both upstream and downstream. The search for this species was carried out by analysing food pellets relating to <em>Strix alucoem>, <em>Tyto albaem> e <em>Athene noctuaem>, thought to be among the most common predators of these intensive herbaceous and arboreal agricultural biocoenosis. The information we gathered was integrated with other Authors' unpublished and bibliographical data. The presence of <em>C. glareolusem> was noted in habitats quite different from the expected ones. Many of the problems raised by the presence of this species in "islands" along the main body of the Po river and its tributaries, and by its presumed absence from particulary suitable environments such as the Carrega woods, the Ticino park and Mesola wood must still be resolved. Riassunto Viene segnalata la presenza di popolazioni di <em>Clethrionomys glareolusem> (Schreber 1790 nella pianura Padana precedentemente considerata al di fuori dell'areale della specie. A partire da una prima serie di catture nell'area golenale del Po presso S. Nazzaro (Monticelli d'Ongina - PC, si è successivamente proceduto ad allargare l'area di ricerca lungo l'argine emiliano del Po, sia a monte sia a valle. La ricerca di questa specie è avvenuta tramite l'analisi di boli alimentari relativi a <em>Strix alucoem>, <em>Tyto albaem> e <em>Athene noctuaem>, ritenuti tra i più comuni predatori di queste biocenosi agricole intensive erbacee ed arboree. I dati da noi raccolti sono stati integrati con quelli bibliografici e inediti di altri Autori. È stata riscontrata la presenza

  14. Comportamento em pastejo e ingestivo de caprinos em sistema silvipastoril

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    Jandson Vieira Costa

    Full Text Available RESUMOFoi avaliado o efeito das diferentes idades de rebrotação da Leucaena leucocephala, associada a gramíneas forrageiras sobre o consumo de forragem e o comportamento de caprinos em sistema silvipastoril. Adotou-se o delineamento inteiramente casualizado com três tratamentos e cinco repetições. Avaliou-se três idades de rebrotação da leucena 45; 60 e 75 dias, com cinco dias de ocupação. O estrato herbáceo foi manejado com idades de 30 dias de rebrotação; foram utilizadas fêmeas mestiças da raça Anglonubiana, cujo comportamento em pastejo foi observado a cada dez minutos, das 8h às 17h. Durante as atividades realizadas pelos animais como ruminação, ócio, deslocamento e pastejo, identificou-se qual a fonte de alimento, se leucena ou estrato herbáceo. A cada duas horas foram aferidas taxa de bocados, levando em consideração o tempo gasto pelos animais para a realização de 20 apreensões. Para a avaliação do consumo foi realizado um teste de pastejo em três dias de ocupação do piquete. O tempo de pastejo foi a atividade mais executada pelos animais com 7,34h e não diferiu significativamente (P>0,05 entre as idades de rebrotação, seguido pelos tempos de deslocamento (1,36h, ruminação (0,51h, e ócio (0,39h. Não houve diferença significativa (P>0,05 para a taxa de bocados, massa de forragem total, taxa de ingestão, e consumo diário. O manejo das idades de rebrotação da leucena em sistema silvipastoril contribui de forma satisfatória para a produção de forragem de leucena e de gramíneas forrageiras e não interfere no comportamento em pastejo e ingestivo de caprinos.As gramíneas constituem-se no componente de maior preferência da dieta dos caprinos no sistema silvipastoril: leucena-gramíneas forrageiras.

  15. Negative-Pressure Cavitation Extraction of Four Main Vinca Alkaloids from <em>Catharanthus em>roseus> Leaves

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    Yuangang Zu

    2012-07-01

    Full Text Available In the present study, an improved method termed negative-pressure cavitation extraction (NPCE followed by reverse phase high-performance liquid chromatography (RP-HPLC was developed for the extraction and quantification of vindoline (VDL, catharanthine (CTR, vincristine (VCR and vinblastine (VLB from <em>Catharanthus roseus em>leaves. The optimized method employed 60-mesh particles, 80% ethanol, a negative pressure of −0.075 MPa, a solid to liquid ratio of 1:20, 30 min of extraction and three extraction cycles. Under these optimized conditions, the extraction yields of VDL, CTR, VCR and VLB are 0.5783, 0.2843, 0.018 and 0.126 mg/g DW, respectively. These extraction yields are equivalent to those from the well-known ultrasonic extraction method and higher than the yields from maceration extraction and heating reflux extraction. Our results suggest that NPCE-RP-HPLC represents an excellent alternative for the extraction and quantification of vinca alkaloids for pilot- and industrial-scale applications.

  16. Conservazione e gestione della Lepre italica (<em>Lepus corsicanusem>

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    Francesco Riga

    2003-10-01

    Full Text Available Il recente riconoscimento dello <em>status> specifico della Lepre italica (<em>Lepus corsicanusem> e l?accertamento dell?areale distributivo rappresentano le azioni più importanti per la conservazione di un <em>taxon endemicoem> che si era creduto estinto. Nella penisola la specie presenta un areale discontinuo, il cui limite settentrionale è dato dal comune di Manciano (GR, sul versante tirrenico e da una linea che dalla provincia de L'Aquila arriva al Gargano. In Sicilia la distribuzione è relativamente continua anche in aree non protette. Dati genetici hanno permesso di confermare la presenza in Corsica. Al contrario, nell?Isola d'Elba, a seguito di estese ricerche, sono stati identificati solo esemplari di <em>L. europaeusem>. Nell?Italia peninsulare <em>L. corsicanusem> è spesso presente in simpatria con popolazioni di <em>L. europaeusem>, mentre in Sicilia la lepre europea non ha originato popolazioni stabili, nonostante l?immissione di molte migliaia di individui. La distribuzione ecologica di <em>L. corsicanusem> ed analisi ambientali specifiche, suggeriscono l?adattamento prevalente agli ambienti a clima mediterraneo, benché essa sia presente anche a quote elevate (> 1.500 m s.l.m.. Dati preliminari di abbondanza relativa hanno evidenziato una situazione diversificata tra la penisola e la Sicilia e tra aree a diverso regime di gestione; un confronto tra le aree protette ha evidenziato rispettivamente valori di 5,54 e 11,73 ind./km². La riduzione quali-quantitativa e la frammentazione dell?<em>habitat> delle lepri è un fenomeno potenzialmente pericoloso per la sopravvivenza delle popolazioni, determinando fenomeni di estinzione locale dovuti alle basse densità di popolazione, inducendo fenomeni di erosione della variabilità genetica e di riduzione della <em>fitness> degli individui. L?introduzione di <em>L. europaeusem> può costituire un importante fattore limitante sia per la possibile competizione

  17. A Comparison of Invasive <em>Acer platanoidesem> and Native <em>A. saccharumem> First-Year Seedlings:<em> em>Growth, Biomass Distribution and the Influence of Ecological Factors<em> em>in a Forest Understory

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    Jacques Brisson

    2012-05-01

    Full Text Available Invasive shade tolerant species can have profound and long-lasting detrimental effects even on previously undisturbed forests. In North American forests, the invasive <em>Acer platanoidesem> is capable of dominating the understory where it could displace the native <em>Acer saccharumem>. To understand the relative importance of various ecological factors in a forest understory on their establishment, we transplanted <em>A. platanoides em>and <em>A. saccharumem> seedlings in an urban sugar maple forest understory and their growth and survival were compared over a growing season. Seedlings did not differ in height, but biomass growth and assimilation rates were twice as high for the invasive species. Ecological variables accounted for only 23–24% of variation in growth. Seedlings of <em>A. platanoidesem> appeared to capture light more efficiently, with over 150% greater foliage biomass and surface area. <em>A. saccharumem> seedlings were more negatively affected by herbivory. The more robust <em>A. platanoides em>seedlings presented characteristics that could allow them to better grow and survive in shaded understories than their native congeners.

  18. Cefaleia em salvas: aspectos clinicos e terapeuticos em 26 casos

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    Wilson Luiz Sanvito

    1980-12-01

    Full Text Available Vinte e seis casos de cefaléia-em-salvas são estudados do ponto de vista clínico e terapêutico. Nos aspectos clínicos são ressaltados a dramaticidade deste tipo de cefaléia, o nítido predomínio no sexo masculino, a média de idade dos pacientes, a presença de manifestações associadas e os fatores desencadeantes das crises nos períodos suscetíveis. Do ponto de vista terapêutico três esquemas medicamentosos foram utilizados: maleato de metisergida, prednisona e associação de ambas as drogas. Em 88,3% dos casos um resultado significativo foi alcançado, traduzido por melhora ou abolição das crises.

  19. <em>Ipomoea aquaticaem> Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity

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    A. Hamid A. Hadi

    2012-05-01

    Full Text Available In the Indian system of traditional medicine (Ayurveda it is recommended to consume <em>Ipomoea em>aquatica> to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of <em>I. aquaticaem> against liver damage were evaluated in thioacetamide (TAA-induced chronic hepatotoxicity in rats. There was no sign of toxicity in the acute toxicity study, in which Sprague-Dawley (SD rats were orally fed with <em>I. aquaticaem> (250 and 500 mg/kg for two months along with administration of TAA (i.p injection 200 mg/kg three times a week for two months. The results showed that the treatment of <em>I. aquaticaem> significantly lowered the TAA-induced serum levels of hepatic enzyme markers (ALP, ALT, AST, protein, albumin, bilirubin and prothrombin time. The hepatic content of activities and expressions SOD and CAT that were reduced by TAA were brought back to control levels by the plant extract supplement. Meanwhile, the rise in MDA level in the TAA receiving groups also were significantly reduced by <em>I. aquaticaem> treatment. Histopathology of hepatic tissues by H&E and Masson trichrome stains displayed that <em>I. aquaticaem> has reduced the incidence of liver lesions, including hepatic cells cloudy swelling, infiltration, hepatic necrosis, and fibrous connective tissue proliferation induced by TAA in rats. Therefore, the results of this study show that the protective effect of <em>I. aquaticaem> in TAA-induced liver damage might be contributed to its modulation on detoxification enzymes and its antioxidant and free radical scavenger effects. Moreover, it confirms a scientific basis for the traditional use of <em>I. aquaticaem> for the treatment of liver disorders.

  20. Fadiga em plataformas offshore fixas com modelos em elementos finitos

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    Roberto Taier

    2002-09-01

    Full Text Available Quatro juntas tubulares de uma plataforma offshore fixa foram modeladas em elementos finitos para o cálculo das vidas à fadiga e comparação com os resultados obtidos através de modelos convencionais em elementos de barras. Foram também cotejados os fatores de concentração de tensões (SCF's, obtidos com base nas formulações paramétricas, com os calculados através dos modelos em elementos finitos. Os objetivos foram averiguar a validade do refinamento do cálculo da fadiga em juntas críticas da plataforma e avaliar as suas conseqüências na elaboração do plano de inspeção. Os resultados permitiram concluir que a análise por elementos finitos torna-se recomendada para juntas que não apresentam tipo e/ou comportamento compatíveis com as configurações padronizadas, normalmente utilizadas pelos programas. Das quatro juntas analisadas, duas delas não necessitariam fazer parte do plano de inspeção da plataforma.Four tubular joints of a fixed offshore platform were modelled using finite elements to evaluate respective fatigue lifes and comparison with the results obtained from conventional models in frame elements. Stress concentration factors (SCF's calculated from parametric formulas were also compared with those obtained from finite elements models. The results of this work have the intention of verifying the validity of the refinement of fatigue analysis on critical joints of the platform and the evaluation of its consequences in the inspection plan. Obtained results show that finite elements analysis is recommended for joints whose type and/or behaviour is not consistent with standard models, used by computational programs. From four analised joints, two of them would not need to be part of inspection plan.

  1. Fatores de risco cardiovascular em alcoolistas em tratamento

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    Mayla Cardoso Fernandes Toffolo

    2013-06-01

    Full Text Available OBJETIVO: Avaliar a presença de fatores de risco cardiovascular, com ênfase na hipertensão e na adiposidade corporal, em alcoolistas abstinentes ou não abstinentes em tratamento. MÉTODO: Trata-se de um estudo transversal com 65 pacientes alcoolistas em tratamento no CAP-Sad. O grau de dependência do álcool foi avaliado pelo SADD (Short Alcohol Dependence Data e o uso de outras drogas, pelo ASSIST (Alcohol Smoking and Substance Involvement Screening Test. Foram avaliados o perfil bioquímico e o antropométrico dos usuários. RESULTADOS: Participaram do estudo 42 homens e 23 mulheres. A maioria dos participantes (67,74% apresentou dependência alcoólica grave, com uso de álcool associado principalmente a cigarro (66,15%. A média da circunferência da cintura (CC foi significativamente maior entre os abstinentes, em comparação aos não abstinentes (AB: 88,15 ± 15,95 x NA: 81,04 ± 9,86; p = 0,03. Pacientes abstinentes há mais tempo tiveram maior sobrepeso/obesidade e adiposidade abdominal (CC do que os não abstinentes e abstinentes recentes, com razão de chances de 5,25. Os abstinentes apresentaram razão de chances de 3,38 para %GC acima da média, independente do tempo de abstinência. CONCLUSÃO: Pacientes alcoolistas abstinentes apresentam mais sobrepeso/ obesidade, adiposidade corporal (%GC e abdominal (CC do que os não abstinentes. É importante o acompanhamento multiprofissional no tratamento de alcoolistas com abordagem para fatores de risco cardiovasculares, principalmente evitando o ganho de peso.

  2. Fadiga em idosos em tratamento quimioterápico

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    Thalyta Cristina Mansano-Schlosser

    2014-07-01

    Full Text Available Pesquisa com delineamento transversal, realizada de agosto a dezembro de 2010, que objetivou identificar a presença e intensidade da fadiga em 140 idosos (média de idade 69,8 anos, 52,1% do sexo feminino com diagnóstico de câncer, em tratamento quimioterápico ambulatorial. Utilizou-se um questionário para caracterização sociodemográfica e clínica e a Escala de Fadiga de Piper-revisada. Identificou-se a presença de fadiga em 60 idosos (42,9% e a causa atribuída foi o câncer (64,1%, a quimioterapia (32,8% e o tratamento (3,1%. Como fator de alívio, os idosos entrevistados relataram "dormir", "rezar" e "morrer", enquanto 45% deles disseram "não ter o que fazer", pois a fadiga não poderia ser aliviada. Espera-se que este estudo alerte os profissionais de enfermagem para a relevância da fadiga e os estimule a identificar e realizar intervenções de enfermagem que visem o adequado manejo desse sintoma no paciente idoso oncológico.

  3. Two New Daucane Sesquiterpenoids from <em>Daphne aurantiacaem>

    Directory of Open Access Journals (Sweden)

    Hao-Fu Dai

    2012-08-01

    Full Text Available Two new daucane sesquiterpenoids 1β,2β-epoxy-10(<em>H>α-dauca-11(12-ene-7α,14-diol (1 and 1α,2α-epoxy-10(<em>H>α-dauca-11(12-ene-7α,14-diol (2 were isolated from the plateau medicinal plant <em>Daphne aurantiacaem> Diels. (Thymelaeceae. Their structures were elucidated by 1D and 2D NMR spectroscopy, as well as HR-ESI-MS data.

  4. Phytochemical Composition, Antioxidant and Xanthine Oxidase Inhibitory Activities of <em>Amaranthus cruentusem> L. and <em>Amaranthus hybridusem> L. Extracts

    Directory of Open Access Journals (Sweden)

    Jeanne F. Millogo

    2012-06-01

    Full Text Available This paper describes a preliminary assessment of the nutraceutical value of <em>Amaranthus cruentus (A. cruentusem> and <em>Amaranthus hybridus (A. hybridusem>, two food plant species found in Burkina Faso. Hydroacetonic (HAE, methanolic (ME, and aqueous extracts (AE from the aerial parts were screened for <em>in vitroem> antioxidant and xanthine oxidase inhibitory activities. Phytochemical analyses revealed the presence of polyphenols, tannins, flavonoids, steroids, terpenoids, saponins and betalains. Hydroacetonic extracts have shown the most diversity for secondary metabolites. The TLC analyses of flavonoids from HAE extracts showed the presence of rutin and other unidentified compounds. The phenolic compound contents of the HAE, ME and AE extracts were determined using the Folin–Ciocalteu method and ranged from 7.55 to 10.18 mg Gallic acid equivalent GAE/100 mg. Tannins, flavonoids, and flavonols ranged from 2.83 to 10.17 mg tannic acid equivalent (TAE/100 mg, 0.37 to 7.06 mg quercetin equivalent (QE /100 mg, and 0.09 to 1.31 mg QE/100 mg, respectively. The betacyanin contents were 40.42 and 6.35 mg Amaranthin Equivalent/100 g aerial parts (dry weight in <em>A. cruentusem> and <em>A. hybridusem>, respectively. Free-radical scavenging activity expressed as IC50 (DPPH method and iron reducing power (FRAP method ranged from 56 to 423 µg/mL and from 2.26 to 2.56 mmol AAE/g, respectively. Xanthine oxidase inhibitory activities of extracts of <em>A. cruentus em>and <em>A. hybridusem> were 3.18% and 38.22%, respectively.<em> em>The> A. hybridusem> extract showed the best antioxidant and xanthine oxidase inhibition activities. The results indicated that the phytochemical contents of the two species justify their traditional uses as nutraceutical food plants.

  5. Phenolic Compounds and Antioxidant Activity of Bulb Extracts of Six <em>Lilium> Species Native to China

    Directory of Open Access Journals (Sweden)

    Lixin Niu

    2012-08-01

    Full Text Available Lily (<em>Lilium> is used as an important edible and medical plant species with a vague taxonomic classification and a long history in China. Bulbs of six <em>Lilium> species (<em>L. regaleem>,> L. concolorem>,> L. pumilumem>,> L. leucanthumem>,> L. davidii var. unicolorem> and <em>L. lancifoliumem> native to China were investigated with a view to their exploitation as a potential source of natural antioxidants due to their phenolic composition and dietary antioxidant potential. The results showed that all bulb extracts exhibited strong antioxidant activities, which generally correlated positively with the total phenolic contents (r = 0.68 to 0.94, total flavonoid contents (r = 0.51 to 0.89 and total flavanol contents (r = 0.54 to 0.95. High-performance liquid chromatography (HPLC analysis revealed that rutin and kaempferol were the major phenolic components in the extracts. Hierarchical cluster analysis showed that <em>L. regaleem> belonged to the group with high phenolic content and strong antioxidant power. <em>L. concolorem> and <em>L. pumilumem> were arranged in one group characterized by moderate phenolic content and antioxidant capacity, while <em>L. leucanthumem>, <em>L. davidii var. unicolorem> and <em>L. lancifoliumem> were clustered in the third group with low phenolic content and weak antioxidant activity. These strongly suggest that lily bulbs may serve as a potential source of natural antioxidant for food and pharmaceutical applications.

  6. Neospora caninum em bovinos em matadouros de Pernambuco e Alagoas

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    Rodolfo L.G. Amaral

    2012-10-01

    Full Text Available A neosporose bovina é uma doença infecciosa causada pelo Neospora caninum, parasito intracelular obrigatório, sendo considerada uma das principais causas de aborto na espécie bovina em diversos países. Objetivou-se estudar a ocorrência de N. caninum em vacas e fetos nos Estados de Pernambuco e Alagoas, Brasil. Foram coletadas 306 amostras de soro sanguíneo de vacas abatidas causada pelo Neospora caninum, parasito intracelular obri-e 30 fetos nos Estados de Pernambuco e Alagoas. Para o gatório, sendo considerada uma das principais causas de diagnóstico sorológico utilizou-se a técnica de Reação de aborto na espécie bovina em diversos países. Objetivou-se Imunoflurescência Indireta (RIFI com ponto de corte estudar a ocorrência de N. caninum em vacas e fetos nos 1:200 para os soros das vacas e para os soros fetais utilizou Estados de Pernambuco e Alagoas, Brasil. Foram coletadas 306 amostras de soro sanguíneo de vacas abatidas e 30 fetos nos Estados de Pernambuco e Alagoas. Para o diagnóstico sorológico utilizou-se a técnica de Reação de Imunoflurescência Indireta (RIFI com ponto de corte 1:200 para os soros das vacas e para os soros fetais utilizou ponto de corte 1:25. Para a pesquisa do DNA parasitário utilizaram-se tecidos fetais submetidos à técnica da Reação em Cadeia da Polimerase (PCR. Na sorologia, observou-se 39/306 (12,6% das vacas positivas e 5/30 (16,7% dos fetos positivos. Na detecção do parasito 8/30 (26,6% dos fetos foram positivos na PCR. Os resultados obtidos neste estudo quanto à presença do parasito nos fetos são inéditos para a região estudada e permitem concluir que este agente deve ser incluído no estudo das causas de aborto na espécie bovina nesta região do Brasil.

  7. <em>Hedyotis diffusaem> Willd Inhibits Colorectal Cancer Growth <em>in Vivoem> via Inhibition of STAT3 Signaling Pathway

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    Jun Peng

    2012-05-01

    Full Text Available Signal Transducer and Activator of Transcription 3 (STAT3, a common oncogenic mediator, is constitutively activated in many types of human cancers; therefore it is a major focus in the development of novel anti-cancer agents. <em>Hedyotis diffusaem> Willd has been used as a major component in several Chinese medicine formulas for the clinical treatment of colorectal cancer (CRC. However, the precise mechanism of its anti-tumor activity remains largely unclear. Using a CRC mouse xenograft model, in the present study we evaluated the effect of the ethanol extract of<em> Hedyotis diffusaem> Willd (EEHDW on tumor growth <em>in vivoem> and investigated the underlying molecular mechanisms. We found that EEHDW reduced tumor volume and tumor weight, but had no effect on body weight gain in CRC mice, demonstrating that EEHDW can inhibit CRC growth <em>in vivoem> without apparent adverse effect. In addition, EEHDW treatment suppressed STAT3 phosphorylation in tumor tissues, which in turn resulted in the promotion of cancer cell apoptosis and inhibition of proliferation. Moreover, EEHDW treatment altered the expression pattern of several important target genes of the STAT3 signaling pathway, <em>i.e.>, decreased expression of Cyclin D1, CDK4 and Bcl-2 as well as up-regulated p21 and Bax. These results suggest that suppression of the STAT3 pathway might be one of the mechanisms by which EEHDW treats colorectal cancer.

  8. Fatigue life estimation of welded joints of an aluminium alloy under superimposed random load waves (follow-up report). Effects o high frequency components; Jujo random kajuka ni okeru aluminium gokin yosetsu tsugite no hiro jumyo suitei (zokuho). Koshuha seibun no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, K.; Maenaka, H.; Takada, A. [Ship Research Inst., Tokyo (Japan)

    1996-06-01

    In the previous paper, fatigue tests of fillet welded T-joints of JIS A 5083P-O Al-Mg alloy for structural members of ship body were conducted under superimposed random load waves in which the secondary fluctuating waveform superimposes on the primary one, to verify the effectiveness of various fatigue life estimation methods. The T-joints used as specimens had welded toes finished by grinder. In this study, boxing welded joints were used. The residual stress measurements, static loading tests, elastic finite element analysis, and fatigue tests were conducted under both constant amplitude and random loads. These tests were conducted under more common conditions. As a result, conclusions obtained are as follows. A reference stress, which was determined as the stress at a distance of 5 mm from a boxing weld toe, was proved effective in reducing the amount of scattering in the fatigue test results, and in improving the accuracy of fatigue life estimation. With regard to the high frequency components, it was required to express the fatigue life using a representative frequency for each stress. 4 refs., 21 figs., 4 tabs.

  9. Grupo Focal em Pesquisas Sociais

    OpenAIRE

    Maria Lúcia Silva Servo; Pricila Oliveira Araújo

    2012-01-01

    Este artigo tem como objetivo discutir a técnica de grupo focal em pesquisas sociais. Apresenta-se as concepções sobre grupo focal. Traz-se os postulados de Pichon-Rivière sobre grupo operativo, os instrumentos de planificação, os vetores do campo grupal para nortear a dinâmica e a observação do campo grupal, bem como a organização, a operacionalização e a análise dos dados das sessões de grupo focal. Através desta técnica de coleta de dados em pesquisas sociais, é possível a construção do EC...

  10. Culturas orais em sociedades letradas

    Directory of Open Access Journals (Sweden)

    Geraldi João Wanderley

    2000-01-01

    Full Text Available Na relação entre linguagem e cultura, um aspecto essencial diz respeito às diferentes funções da escrita e às formas de sua apropriação social em sociedades letradas. Tomando como inspiração a forma de um uso específico da escrita pelo povo indígena Jarawara e narrativas de ribeirinhos do rio Madeira do mito amazônico Cobra Norato, são discutidas as diferentes relações entre oralidade e escrita que, atravessadas pelas relações de poder, transformam o alfabeto, de artefato histórico construído para o registro da oralidade, em espaço social de construção de distinções, clivagens e exclusões.

  11. Grupo Focal em Pesquisas Sociais

    OpenAIRE

    Maria Lúcia Silva Servo; Pricila Oliveira Araújo

    2012-01-01

    Este artigo tem como objetivo discutir a técnica de grupo focal em pesquisas sociais. Apresenta-se as concepções sobre grupo focal. Traz-se os postulados de Pichon-Rivière sobre grupo operativo, os instrumentos de planificação, os vetores do campo grupal para nortear a dinâmica e a observação do campo grupal, bem como a organização, a operacionalização e a análise dos dados das sessões de grupo focal. Através desta técnica de coleta de dados em pesquisas sociais, é possível a construção do EC...

  12. Bacharelado em psicopedagogia = Psycopedagogy Course

    Directory of Open Access Journals (Sweden)

    Ramos, Maria Beatriz Jacques

    2007-01-01

    Full Text Available Este texto mostra a história da implantação do Curso de Bacharelado em Psicopedagogia na FACED, PUCRS. Neste texto são apresentados os referenciais teóricos e dados sobre a atuação do psicopedagogo nos campos preventivo e terapêutico explicitando a relevância da formação de profissionais nesta área

  13. Iatrogenia em pacientes idosos hospitalizados

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    Carvalho-Filho Eurico T.

    1998-01-01

    Full Text Available Analisar as complicações iatrogênicas apresentadas por idosos hospitalizados. Estudo retrospectivo dos prontuários de 96 pacientes, 48 do sexo masculino e 48 do feminino, com idades variando de 60 a 93 anos (média: 75,7 anos, hospitalizados durante o ano de 1995 em enfermaria geriátrica. A análise da evolução dos pacientes durante o período de hospitalização permitiu evidenciar: 1 em 42 (43,7% pacientes ocorreram uma ou mais complicações iatrogênicas, num total de 56 episódios; 2 manifestações relacionadas aos procedimentos diagnósticos corresponderam a 17,9% das iatrogenias; 3 alterações relacionadas às medidas terapêuticas corresponderam a 58,9%, sendo 32,1% referentes à terapêutica farmacológica e 26,8% a outros procedimentos terapêuticos; 4 manifestações iatrogênicas não relacionadas diretamente às afecções (úlceras de decúbito, quedas e fraturas corresponderam a 23,2%; 5 a presença de manifestações iatrogênicas correlacionou-se com período mais prolongado de internação; 6 cinco pacientes faleceram em conseqüência direta de complicações iatrogênicas. A iatrogenia é freqüente em pacientes idosos hospitalizados, podendo determinar manifestações graves e mesmo fatais. Como uma significativa proporção dessas complicações pode ser evitada através de medidas adequadas, deve-se procurar identificar suas causas e desenvolver métodos para previni-la ou reduzir seus efeitos.

  14. Iatrogenia em pacientes idosos hospitalizados

    Directory of Open Access Journals (Sweden)

    Eurico T. Carvalho-Filho

    1998-02-01

    Full Text Available Analisar as complicações iatrogênicas apresentadas por idosos hospitalizados. Estudo retrospectivo dos prontuários de 96 pacientes, 48 do sexo masculino e 48 do feminino, com idades variando de 60 a 93 anos (média: 75,7 anos, hospitalizados durante o ano de 1995 em enfermaria geriátrica. A análise da evolução dos pacientes durante o período de hospitalização permitiu evidenciar: 1 em 42 (43,7% pacientes ocorreram uma ou mais complicações iatrogênicas, num total de 56 episódios; 2 manifestações relacionadas aos procedimentos diagnósticos corresponderam a 17,9% das iatrogenias; 3 alterações relacionadas às medidas terapêuticas corresponderam a 58,9%, sendo 32,1% referentes à terapêutica farmacológica e 26,8% a outros procedimentos terapêuticos; 4 manifestações iatrogênicas não relacionadas diretamente às afecções (úlceras de decúbito, quedas e fraturas corresponderam a 23,2%; 5 a presença de manifestações iatrogênicas correlacionou-se com período mais prolongado de internação; 6 cinco pacientes faleceram em conseqüência direta de complicações iatrogênicas. A iatrogenia é freqüente em pacientes idosos hospitalizados, podendo determinar manifestações graves e mesmo fatais. Como uma significativa proporção dessas complicações pode ser evitada através de medidas adequadas, deve-se procurar identificar suas causas e desenvolver métodos para previni-la ou reduzir seus efeitos.

  15. COMPETÊNCIA EM MEDICINA

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    Hélio Teixeira MD.

    2005-01-01

    Full Text Available Competência no exercício da medicina depende de um processo evolutivo ao longo da vida do profissional, processo este fundamentado em eficiência, experiência e em princípios éticos. A eficiência depende da cultura médica, de habilidades técnicas e relacionamento interpessoal com o paciente. A experiência ao longo da vida vai refinando o médico, favorecendo o evolver do conhecimento e da sabedoria vivencial. Finalmente, a ética médica se fundamenta na justiça, compaixão e amor ao próximo. Didaticamente, distinguimos 3 fases da evolução profissional do médico: a infância profissional ou visão linear: o médico se restringe em geral ao atendimento da doença, negligenciando o doente. É quase exclusivamente técnico e tem percepção acanhada da medicina-arte. b Maturidade profissional ou visão humanística: resultado de evolução da personalidade, da cultura e da experiência do médico, agora voltado para o doente com sua doença. c Excelência profissional ou visão holística: estágio máximo que se pode alcançar, quando o médico vislumbra a si e ao seu cliente em todas suas dimensões integradas e atua como mestre, procurando despertar no paciente condições próprias de cura, oriundas de sua essência. Conclui-se que exercer medicina com competência significa desempenhar adequadamente a ciência e a arte médica.

  16. Adding large EM stack support

    KAUST Repository

    Holst, Glendon

    2016-12-01

    Serial section electron microscopy (SSEM) image stacks generated using high throughput microscopy techniques are an integral tool for investigating brain connectivity and cell morphology. FIB or 3View scanning electron microscopes easily generate gigabytes of data. In order to produce analyzable 3D dataset from the imaged volumes, efficient and reliable image segmentation is crucial. Classical manual approaches to segmentation are time consuming and labour intensive. Semiautomatic seeded watershed segmentation algorithms, such as those implemented by ilastik image processing software, are a very powerful alternative, substantially speeding up segmentation times. We have used ilastik effectively for small EM stacks – on a laptop, no less; however, ilastik was unable to carve the large EM stacks we needed to segment because its memory requirements grew too large – even for the biggest workstations we had available. For this reason, we refactored the carving module of ilastik to scale it up to large EM stacks on large workstations, and tested its efficiency. We modified the carving module, building on existing blockwise processing functionality to process data in manageable chunks that can fit within RAM (main memory). We review this refactoring work, highlighting the software architecture, design choices, modifications, and issues encountered.

  17. Existe sujeito em Michel Maffesoli?

    Directory of Open Access Journals (Sweden)

    Marli Appel da Silva

    2010-06-01

    Full Text Available Este ensaio discute a concepção de sujeito na abordagem teórica de Michel Maffesoli. As ideias desse autor estão em voga em alguns meios acadêmicos no Brasil e são difundidas por algumas mídias de grande circulação nacional. Entretanto, ao longo de suas obras, os pressupostos que definem quem é o sujeito maffesoliano se encontram pouco clarificados. Portanto, para alcançar o objetivo a que se propõe, este ensaio desenvolve uma análise da epistemologia e da ontologia maffesoliana com a finalidade de compreender as origens dos pressupostos desse autor, ou seja, as teorias e os autores em que Maffesoli se baseou para desenvolver uma visão de sujeito. Com essa compreensão, pretende-se responder à questão: existe sujeito na abordagem teórica de Maffesoli.

  18. Complaints against an EMS system.

    Science.gov (United States)

    Colwell, Christopher B; Pons, Peter T; Pi, Randy

    2003-11-01

    Complaints against Emergency Medical Services (EMS) agencies represent a concerning and potentially time-consuming problem for all involved in the delivery of prehospital emergency medical care. The objective of this study was to identify the source of complaints against an EMS system to help focus quality and performance improvement and customer service efforts. We conducted a retrospective review of complaints filed against a busy urban EMS agency over a 6-year period. All complaints were included, totaled by season and by year, and categorized by originator and nature of the complaint. A total of 286 complaints were registered during the 6-year period, with an average of 48 per year and 9.3 per 10,000 responses. The most common originators of complaints were patients (53%) followed by medical personnel (19%) and family members or friends (12%). Rude behavior accounted for 23% of the complaints registered, followed by technical skills (20%), transport problems (18%), and loss of belongings (13%). The identification of areas of dissatisfaction will allow focused quality and performance improvement programs directed at customer service and risk management.

  19. Divisão de trabalho em cuidados à prole em Sicalis flaveola (Linnaeus, 1766 (Passeriformes, Emberizidae, em cativeiro

    Directory of Open Access Journals (Sweden)

    Luiz Octavio Marcondes-Machado

    1988-01-01

    Full Text Available São relatadas observações relativas à divisão de trabalho em cuidados à prole em Sicalis flaveola brasiliensis (Gmelin e S. f. pelzelni (Sclater, em condições de cativeiro.Observations relating to the division of labour for young care in Sicalis flaveola brasiliensis (Gmelin and S. f. pelzelni (Sclater, in captivity, are presented.

  20. Paratuberculose em ruminantes no Brasil

    Directory of Open Access Journals (Sweden)

    Elise M. Yamasaki

    2013-02-01

    Full Text Available A paratuberculose ou doença de Johne é uma enterite granulomatosa causada por Mycobacterium avium subsp. paratuberculosis (Map e comumente afeta ruminantes domésticos, no entanto, pode infectar várias espécies de mamíferos. Está presente nos cinco continentes e é considerada endêmica em algumas regiões pela Organização Internacional de Epizootias (OIE. Pertence à lista de enfermidades notificáveis, que compreende as doenças transmissíveis de importância sócio-econômica e/ou em saúde-pública, cujo controle é necessário para o comércio internacional de animais e alimentos de origem animal. A importância da doença de Johne não se restringe somente aos prejuízos econômicos causados à indústria animal, mas também na possível participação do Map na íleocolite granulomatosa que afeta seres humanos, conhecida como doença de Crohn. No Brasil, a paratuberculose já foi descrita em diversas espécies de ruminantes e em vários estados. Embora os relatos naturais da enfermidade sejam pontuais, acredita-se na possibilidade da transmissão interespecífica e na disseminação do agente através da compra e venda de animais infectados. O objetivo deste artigo foi reunir as informações disponíveis referentes aos aspectos epidemiológicos, clínico-patológicos e laboratoriais da paratuberculose em bovinos, bubalinos, caprinos e ovinos no Brasil, e salientar a necessidade de implementação de medidas de controle sanitário da enfermidade no país, o que possibilitaria a melhoria da qualidade e valorização dos produtos de origem animal no mercado internacional.

  1. Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from <em>Rosmarinus officinalisem>>

    Directory of Open Access Journals (Sweden)

    Chunjian Zhao

    2012-09-01

    Full Text Available Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from <em>Rosmarinus officinalisem>. Eight ionic liquids, with different cations and anions, were investigated in this work and [C8mim]Br was selected as the optimal solvent. Ultrasound extraction parameters, including soaking time, solid–liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology. The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from <em>R. officinalisem>> em>compared with traditional reference extraction methods. Ionic liquids are considered to be green solvents, in the ultrasound-assisted extraction of key chemicals from medicinal plants, and show great potential.

  2. Trophic systems and chorology: data from shrews, moles and voles of Italy preyed by the barn owl / Sistemi trofici e corologia: dati su <em>Soricidae>, <em>Talpidae> ed <em>Arvicolidae> d'Italia predati da <em>Tyto albaem> (Scopoli 1769

    Directory of Open Access Journals (Sweden)

    Longino Contoli

    1986-12-01

    Full Text Available Abstract In small Mammals biogeography, available data are up to now by far too scanty for elucidate the distribution of a lot of taxa, especially with regard to the absence from a given area. In this respect, standardized quantitative sampling techniques, like Owl pellets analysis can enable not only to enhance faunistic knowledges, but also to estimate the actual absence probability of a given taxon "m", lacking from the diet of an individual raptor. For the last purpose, the relevant frequencies of "m" in the other ecologically similar sites of the same raptor species diets are averaged ($f_m$ : the relevant standard error (multiplicated by a coefficient, according to the desired degree of accuracy, in relation of the integral of probabilities subtracted ($overline{F}_m - a E$: then, the probability that a single specimen is not pertaining to "m" is obtained ($P_0 = 1 - F_m + a E$; lastly, the desiderate accuracy probability ($P_d$ is chosen. Now, "$N_d$" (the number of individuals of all prey species in a single site needed for obtain, with the desired probability, a specimen at least of "m" is obtained through $$N = frac{ln P_d}{ln P_0}$$ Obviously, every site-diet with more than "N" preyed individuals and without any "i" specimen is considered to be lacking of such taxon. A "usefulness index" for the above purposes is outlined and checked about three raptors. Some exanples about usefulness of the Owl pellet analysis method in biogeography are given, concerning <em>Tyto albaem> diets in peninsular Italy about: - <em>Sorex minutusem>, lacking in some quite insulated areas; - <em>Sorex araneusem> (sensu stricto, after GRAF et al., 1979, present also in lowland areas in Emilia-Romagna; - <em>Crocidura suaveolensem> and - <em>Suncus etruscusem>, present also in the southermost part of Calabria (Reggio province; - <em>Talpa caecaem>, present also in the Antiapennines of Latium (Cimini mounts; - <em>Talpa romanaem

  3. Morphological identification of the Soprano Pipistrelle (<em>Pipistrellus pygmaeusem> Leach, 1825 in Croatia.

    Directory of Open Access Journals (Sweden)

    Igor Pavlinić

    2008-07-01

    Full Text Available Abstract After the discovery of two different phonic types within the common pipistrelle (<em>Pipistrellus pipistrellusem>, mtDNA analysis confirmed the existence of two separate species named as common pipistrelle (<em>P. pipistrellusem> and soprano pipistrelle (<em>P. pygmaeusem>. The discrimination of these two cryptic species using external characters and measures has proved to be somewhat problematic. We examined two colonies of soprano pipistrelle from Donji Miholjac, Croatia. As a result, only two characters proved to be of help for field identification: wing venation (89% of cases and penis morphology and colour for males. The difference in length between the 2nd and 3rd phalanxes of the 3rd finger should be discarded as diagnostic trait between <em>P. pipistrellusem> and <em>P. pygmaeusem> in Croatia. Riassunto Identificazione su basi morfologiche del pipistrello pigmeo (<em>Pipistrellus pygmeausem>, Leach, 1825 in Croazia. A seguito della descrizione di due differenti "tipi fonici" nel pipistrello nano (<em>Pipistrellus pipistrellusem> e della successiva conferma su basi genetiche dell'esistenza di due specie distinte, designate come pipistrello nano (<em>P. pipistrellusem> e pipistrello pigmeo (<em>P. pygmaeusem>, la distinzione delle due specie in base a caratteristiche morfologiche esterne si è dimostrata un problema di difficile soluzione. Sulla base delle caratteristiche distintive e delle differenze biometriche proposte da altri Autori, sono state esaminate due colonie di pipistrello pigmeo a Donji Miholjac, in Croazia. I risultati ottenuti evidenziano che, tra tutti i potenziali caratteri sinora proposti, solo due risultano utili per un'identificazione diretta sul campo: la venatura delle ali, risultata utile alla discriminazione nell'89% degli esemplari analizzati, e la colorazione e morfologia del pene nei maschi. La

  4. Variabilità morfologica ed ecologica in <em>Neomys fodiensem> e <em>Neomys anomalusem> nell'Appennino settentrionale

    Directory of Open Access Journals (Sweden)

    Dino Scaravelli

    2003-10-01

    Full Text Available I due <em>Neomys> italiani sono ancora da chiarire dal punto di vista della loro caratterizzazione morfologica e ecologica. Il lavoro prende in considerazione un campione di entrambe le specie proveniente da habitat forestali dell?Appennino settentrionale per i quali sono stati identificati i principali parametri ambientali. Vengono quindi descritte la variabilità dei tratti morfologici delle due specie in aree localizzate nel Parco Nazionale Foreste Casentinesi, Monte Falterona e Campigna nell?Appennino tosco-romagnolo. Risultano di sicuro effetto discriminatorio la maschera facciale, il rapporto piede posteriore/coda e i caratteri cranici. Sulla base dei criteri identificativi si sono realizzate rilevazioni di misure corporee per le due specie e una comparazione degli habitat utilizzati. <em>N. fodiensem> appare unica specie nelle faggete-abetine e dominante nei castagneti, mentre nell?Ontaneta e nelle zone aperte e termofile si registra la sola presenza di <em>N. anomalusem>. Mancano entrambi nei prati cespugliati, nella pecceta e nella cerreta. I gradienti presenti sono quindi illustrati. Non appare una differenza altitudinale nel campione esaminato, posto in stazioni tra i 400 e i 1300 m, ma per entrambe vi sono maggiori riscontri nella fascia tra 700 e 850 m. Nell?analisi multivariata rispetto alle altre specie e alle variabili ambientali si riscontra sempre una discreta correlazione con la presenza di acqua di una certa ampiezza, che comunque è significativa solo per <em>N. fodiensem>, mentre risulta di interesse la positiva correlazione di <em>N. anomalusem> con <em>Apodemus sylvaticusem>.

  5. Briareolate Esters from the Gorgonian <em>Briareum asbestinumem>

    Directory of Open Access Journals (Sweden)

    Lyndon M. West

    2012-08-01

    Full Text Available Two new briarane diterpenoids briareolate esters J (1 and K (2 were isolated from the methanolic extract of the octocoral <em>Briareum> asbestinum em>collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2 showed weak growth inhibition activity against human embryonic stem cells (BG02.

  6. Benzyl 2-β-Glucopyranosyloxybenzoate, a New Phenolic Acid Glycoside from <em>Sarcandra glabraem>

    Directory of Open Access Journals (Sweden)

    Xudong Xu

    2012-05-01

    Full Text Available From the whole plant of <em>Sarcandra glabraem>, a new phenolic acid glycoside, benzyl 2-β-glucopyranosyloxybenzoate (1, together with seven known compounds including eleutheroside B1 (2, 5-<em>O>-caffeoylshikimic acid (3, (–-(7<em>S>, 8<em>R>-dihydrodehydro-diconiferyl alcohol (4, (–-(7<em>S>, 8<em>R>-dihydrodehydrodiconiferyl alcohol 9-, 9′- and 4-<em>O>-â-D-glucopyranoside (57, and (–-(7<em>S>, 8<em>R>-5-methoxydihydrodehydrodiconiferyl alcohol 4-<em>O>-β-D-glucopyranoside (8 was isolated. Their structures were elucidated by spectral analysis including 1D-, 2D-NMR and HR-ESI-MS. Compound 2 was found to exhibit potent cytotoxic activity against BGC-823 and A2780 cancer cell lines using MTT method with IC50 value of 2.53 and 1.85 µM, respectively.

  7. Lectin from <em>Canavalia brasiliensisem> Seeds (ConBr Is a Valuable Biotechnological Tool to Stimulate the Growth of <em>Rhizobium tropiciem> <em>in Vitroem>

    Directory of Open Access Journals (Sweden)

    Ricardo Pires dos Santos

    2012-05-01

    Full Text Available To study the interactions between a <em>Rhizobium tropiciem> strain and lectins isolated from the seeds of <em>Canavalia ensiformisem> (ConA and <em>Canavalia brasiliensisem> (ConBr, a lectin fluorescence assay was performed. In addition, an experiment was designed to evaluate the effect of the two lectins on bacterial growth. Both lectins were found to bind to <em>R. tropiciem> cells, but the interactions were inhibited by D-mannose. Interestingly, only ConBr stimulated bacterial growth in proportion to the concentrations used (15.6–500 µg/mL, and the bacterial growth stimulation was inhibited by D-mannose as well. Structure/Function analyses by bioinformatics were carried out to evaluate the volume and carbohydrate recognition domain (CRD configuration of ConA and ConBr. The difference of spatial arrangement and volume of CRD may indicate the variation between biological activities of both lectins. The results suggest that ConBr could be a promising tool for studies focusing on the interactions between rhizobia and host plants.

  8. Acrilamida em doçaria Portuguesa

    OpenAIRE

    Jesus, Susana; Delgado, Inês; Ramos, Ana; Brandão, Carlos; Félix, Nelson; Castanheira, Isabel

    2015-01-01

    A acrilamida é um composto de estrutura vinílica, com propriedades carcinogénicas (Grupo 2A- IARC) que tem vindo a ser identificado, em alimentos processados, desde 2002. Segundo os últimos documentos publicados pela EFSA deve ser prioritário a determinação do teor de acrilamida em produtos de panificação e pastelaria. Este estudo teve como objetivo a determinação da quantidade de acrilamida em doçaria portuguesa. Trinta amostras de doces e pão fabricados em estabelecimentos hoteleiros do Nor...

  9. Biocerâmicas em Endodontia

    OpenAIRE

    Oliveira, Pedro Miguel da Silva

    2014-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária Introdução e Objectivos: Biocerâmicas incluem materiais cerâmicos projetados especificamente para uso em Medicina e Medicina Dentária. O objetivo deste trabalho é efetuar uma revisão bibliográfica em que demonstre a avaliação das propriedades físico-químicas das biocerâmicas e o seu uso em Endodontia. Radiopacidade, Fluid...

  10. Encapsulation-Induced Stress Helps <em>Saccharomyces cerevisiae em>Resist Convertible Lignocellulose Derived Inhibitors

    Directory of Open Access Journals (Sweden)

    Johan O. Westman

    2012-09-01

    Full Text Available The ability of macroencapsulated <em>Saccharomyces cerevisiae em>CBS8066<em> em>to withstand readily and not readily <em>in situem> convertible lignocellulose-derived inhibitors was investigated in anaerobic batch cultivations. It was shown that encapsulation increased the tolerance against readily convertible furan aldehyde inhibitors and to dilute acid spruce hydrolysate, but not to organic acid inhibitors that cannot be metabolized anaerobically. Gene expression analysis showed that the protective effect arising from the encapsulation is evident also on the transcriptome level, as the expression of the stress-related genes <em>YAP1em>, <em>ATR1em> and <em>FLR1em> was induced upon encapsulation. The transcript levels were increased due to encapsulation already in the medium without added inhibitors, indicating that the cells sensed low stress level arising from the encapsulation itself. We present a model, where the stress response is induced by nutrient limitation, that this helps the cells to cope with the increased stress added by a toxic medium, and that superficial cells in the capsules degrade convertible inhibitors, alleviating the inhibition for the cells deeper in the capsule.

  11. Soja integral processada em dietas para codornas japonesas em postura

    OpenAIRE

    Barreto,Sergio Luiz de Toledo; Moura,Weyllison César Oliveira; Reis,Renata de Souza; Hosoda,Lúcia Reiko; Maia,Gustavo Vaz Corrêa; Pena,Graciane de Miranda

    2010-01-01

    Objetivou-se avaliar o desempenho de codornas japonesas na fase de postura alimentadas com dietas contendo soja integral processada. Utilizaram-se 320 codornas japonesas fêmeas com 29 semanas de idade e peso inicial de 186,1 ± 4,0 g, distribuídas em delineamento inteiramente casualizado, com oito repetições, cada uma com dez aves por unidade experimental. As dietas foram isocalóricas e isonutritivas para proteína bruta, lisina digestível, metionina + cistina digestível, cálcio, fósforo dispon...

  12. Tumores em bovinos encontrados em abatedouros frigoríficos

    Directory of Open Access Journals (Sweden)

    Bianca Tessele

    2016-03-01

    Full Text Available Resumo: Numa pesquisa em abatedouros a procura de lesões em bovinos, realizada de janeiro de 2011 a julho de 2014, 544 foram encontradas, das quais 65 eram neoplasmas. Quarenta e dois porcento desses tumores eram de origem mesenquimal; 37% eram epiteliais; 14,5% eram derivados da crista neural; 5% eram tumores do cordão sexual; e 1,5 eram tumores originários do sistema nervoso periférico. O tumor mais frequentemente encontrado foi o linfoma (28% de todos os tumores, a maioria dos casos como parte do complexo leucose bovina enzoótica. O carcinoma de células escamosas foi o segundo tumor mais frequente (15% de todos os tumores. É chamada a atenção para a frequência desses tumores e para a sua importância no diagnóstico diferencial no abatedouro frigorífico entre eles e outras lesões importantes, incluindo as lesões granulomatosas da tuberculose. Houve uma ocorrência significativa do feocromocitoma adrenal (13% de todos os tumores. Papilomatose representou apenas 3% de todos os tumores. Como papilomas são comuns em bovinos, seu baixo número nesse estudo pode ser explicado pelo fato de que eles não são usualmente diagnosticados no exame post mortem (quando o couro já foi retirado da carcaça, mas sim no exame ante mortem, como ocorreu na maioria dos casos deste estudo. Tumores encontrados com menor frequência (cada um perfazendo entre 1.5 e 3% de todos os tumores incluíram adenocarcinoma apócrino misto da cauda, adenocarcinoma mamário, adenocarcinoma uterino, carcinoma de células renais, fibroma interdigital, hemangiossarcoma, leiomioma uterino, lipoma, lipossarcoma, mesotelioma, neurofibroma, tumor de células da granulosa, tumor estromal gastrointestinal, tumores hepáticos, tumores melanocíticos, e tumores pulmonares primários. Pretende-se que os resultados dessa pesquisa possam ajudar na identificação das lesões na inspeção oficial em matadouros frigoríficos.

  13. Meningoencefalite granulomatosa em bovinos em pastoreio de ervilhaca (Vicia spp)

    OpenAIRE

    Rech, Raquel R.; Rafael A. Fighera; Oliveira, Fabiano N.; Claudio S.L. Barros

    2004-01-01

    Meningoencefalite granulomatosa foi observada em 7 de 8 vacas leiteiras adultas afetadas por doença granulomatosa sistêmica associada ao consumo de ervilhaca, embora nenhum dos bovinos afetados apresentasse sinais de distúrbios nervosos. Os infiltrados inflamatórios localizavam-se nas leptomeninges e como manguitos perivasculares no interior do encéfalo; consistiam de macrófagos epitelióides, linfócitos, plasmócitos e eosinófilos. Essas alterações inflamatórias variavam de leves a acentuadas ...

  14. <em>Plecotus alpinusem>: primi dati sull'utilizzo dell'habitat

    Directory of Open Access Journals (Sweden)

    Adriano Martinoli

    2003-10-01

    Full Text Available Negli ultimi anni il numero delle specie di Chirotteri note per l?Europa si è accresciuto, grazie all?uso di tecniche di genetica molecolare, ed in particolare il genere <em>Plecotus> è quello che ha registrato maggiori cambiamenti con la descrizione di tre nuove specie: <em>Plecotus kolombatoviciem>, <em>P. alpinusem> e <em>P. sardusem> (Kiefer & Veith, 2001; Mucedda <em>et al.em>, 2002. Alla luce di queste nuove scoperte, la distribuzione geografica e le preferenze dell?habitat delle due specie ?storiche? di Orecchione in Europa, <em>Plecotus auritusem> e <em>P. austriacusem>, dovrebbero essere riviste: in questo contesto si inserisce l?indagine svolta nel Parco Regionale Campo dei Fiori (in provincia di Varese sulla prima colonia riproduttiva di <em>Plecotus alpinusem> segnalata per la regione Lombardia. Al fine di valutare le preferenze nell?uso dell?habitat e le direttrici di spostamento preferenziali di tale specie, nonché per l?identificazione di siti di rilevanza per l?allevamento della prole, si è fatto ricorso a tecniche di radiolocalizzazione, subordinate alla cattura a vivo degli animali. Le catture si sono svolte nel periodo 15 giugno ? 15 agosto del 2002 e del 2003. Per ogni individuo catturato, oltre alla determinazione di specie, sesso e classe d?età, sono stati rilevati i dati biometrici e prelevati campioni di tessuto destinati all?analisi genetica. Sono state inoltre registrate le emissioni ultrasonore. Durante il primo anno di indagine sono state seguite mediante radiolocalizzazione 5 femmine adulte (4 allattanti ed una non allattante e due femmine subadulte, mentre durante il secondo anno sono state munite di radiocollare 6 femmine adulte (5 allattanti ed una non allattante ed una femmina subadulta. Ai pipistrelli è stato applicato un emettitore radio (<em>tag> modello LB-2, Holohil Systems Ltd, Ontario, Canada. Il segnale emesso è stato ricevuto in campo mediante l?utilizzo di radio (Wildlife

  15. Altitudinal distribution of the common longeared bat <em>Plecotus auritusem> (Linnaeus, 1758 and grey long-eared bat <em>Plecotus austriacusem> (J. B. Fischer, 1829 (Chiroptera, Vespertilionidae in the Tatra mountains (southern Poland

    Directory of Open Access Journals (Sweden)

    Krzysztof Piksa

    2006-03-01

    Full Text Available Riassunto Distribuzione altitudinale di Orecchione bruno (<em>Plecotus auritusem> e Orecchione meridionale (<em>Plecotus austriacusem> nei Monti Tatra (Polonia meridionale. Vengono riportati nuovi dati relativi alla distribuzione altitudinale nei Monti Tatra (Polonia meridionale di <em>Plecotus auritusem> e <em>P. austriacusem>. Tali segnalazioni incrementano le conoscenze relative alla presenza di questi chirotteri a quote elevate, in particolare per la Polonia. In inverno <em>P. auritusem> è stato rinvenuto a 1921 m s.l.m. mentre in estate è stato rinvenuto a 2250 m s.l.m.; in aggiunta, sono stati ritrovati resti ossei a 1929 m s.l.m. <em>P. austriacusem> è stato segnalato in ibernazione a 1294 m s.l.m.

  16. Jonas Mekas - cinema em lampejos

    Directory of Open Access Journals (Sweden)

    Bruna Machado Ferreira

    2015-06-01

    Full Text Available http://dx.doi.org/10.5007/2175-7917.2015v20n2p55 Este artigo apresenta reflexões acerca da criação cinematográfica de Jonas Mekas, um dos realizadores e pensadores do cinema de vanguarda norte-americano, que, como tal, traz, em seus filmes, a marca da reproposição da linguagem/montagem, uma outra compreensão do tempo e sua passagem, via o abandono da cronologia e de qualquer linearidade narrativa. A partir deste argumento, desdobra-se a leitura de um cinema que se faz no e pelo deslocamento, o trânsito pelo cotidiano, abertura para o acaso, contingência; que não parte de uma unidade espaço-temporal, mas se fragmenta – fragmento este que se apresenta como possibilidade ética diante da alteridade; passagens, rastros, vestígios de um gesto. Cenas que projetam o íntimo no público em uma espécie de celebração contínua e despretensiosa do cotidiano, do familiar. Cinema em exílio, cinema-asilo - ao mesmo tempo, sobrevivência e suspensão de uma memória, abrigo do corpo, da linguagem, do encontro, onde parece sempre se desenhar a possibilidade, abertura para a invenção de um espaço novo, inédito, espaço-vida, espaço-arte, sem fronteiras.

  17. DOE/EM Criticality Safety Needs Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Westfall, Robert Michael [ORNL; Hopper, Calvin Mitchell [ORNL

    2011-02-01

    The issue of nuclear criticality safety (NCS) in Department of Energy Environmental Management (DOE/EM) fissionable material operations presents challenges because of the large quantities of material present in the facilities and equipment that are committed to storage and/or material conditioning and dispositioning processes. Given the uncertainty associated with the material and conditions for many DOE/EM fissionable material operations, ensuring safety while maintaining operational efficiency requires the application of the most-effective criticality safety practices. In turn, more-efficient implementation of these practices can be achieved if the best NCS technologies are utilized. In 2002, DOE/EM-1 commissioned a survey of criticality safety technical needs at the major EM sites. These needs were documented in the report Analysis of Nuclear Criticality Safety Technology Supporting the Environmental Management Program, issued May 2002. Subsequent to this study, EM safety management personnel made a commitment to applying the best and latest criticality safety technology, as described by the DOE Nuclear Criticality Safety Program (NCSP). Over the past 7 years, this commitment has enabled the transfer of several new technologies to EM operations. In 2008, it was decided to broaden the basis of the EM NCS needs assessment to include not only current needs for technologies but also NCS operational areas with potential for improvements in controls, analysis, and regulations. A series of NCS workshops has been conducted over the past years, and needs have been identified and addressed by EM staff and contractor personnel. These workshops were organized and conducted by the EM Criticality Safety Program Manager with administrative and technical support by staff at Oak Ridge National Laboratory (ORNL). This report records the progress made in identifying the needs, determining the approaches for addressing these needs, and assimilating new NCS technologies into EM

  18. Brasil em obras, peões em luta, sindicatos surpreendidos

    Directory of Open Access Journals (Sweden)

    Roberto Véras

    2014-05-01

    Full Text Available O presente artigo aborda as revoltas e greves ocorridas em março de 2011 em canteiros de obras do Programa de Aceleração do Crescimento (PAC, do Governo Federal, que alcançou grande repercussão nacional. Tem como foco os conflitos e as negociações, envolvendo trabalhadores, sindicatos, empresários, Governo, Justiça, Ministério Público do Trabalho, entre outros atores, estabelecidos durante a construção das Usinas Hidroelétricas de Jirau e Santo Antônio, situadas no Norte do país. Visou identificar as posições dos referidos atores e, sob uma perspectiva sociológica, propor reflexões sobre as potencialidades e os limites da atividade sindical. Que questões trouxeram tais acontecimentos ao sindicalismo, quanto às relações deste, de um lado, com suas próprias bases e, de outro, com o atual projeto governamental?

  19. B-norsteroids from <em>Hymenoscyphus pseudoalbidusem>

    Directory of Open Access Journals (Sweden)

    Pierre F. Andersson

    2012-06-01

    Full Text Available Two viridin-related B-norsteroids, B-norviridiol lactone (1 and B-norviridin enol (2, both possessing distinct unprecedented carbon skeletons, were isolated from a liquid culture of the ash dieback-causing fungus <em>Hymenoscyphus pseudoalbidusem>. Compound 2 was found to degrade to a third B-norsteroidal compound, 1β-hydroxy-2α-hydro-asterogynin A (3, which was later detected in the original culture. The proposed structure of 1 is, regarding connectivity, identical to the original erroneous structure for TAEMC161, which was later reassigned as viridiol. Compound 2 showed an unprecedented 1H-13C HMBC correlation through an intramolecular hydrogen bond. The five-membered B-ring of compounds 1–3 was proposed to be formed by a benzilic acid rearrangement. The known compound asterogynin A was found to be formed from 3 by a β-elimination of water. All compounds were characterized by NMR spectroscopy, LC-HRMS and polarimetry.

  20. EM transmission-line metamaterials

    Directory of Open Access Journals (Sweden)

    George V. Eleftheriades

    2009-03-01

    Full Text Available Metamaterials are understood to be artificially engineered materials that exhibit unusual or difficult to obtain electromagnetic (EM properties. Such properties would include negative or low values of permittivity, permeability and index of refraction. In this article, we review the fundamentals of metamaterials with emphasis on negative-refractive-index ones, which are synthesized using loaded transmission lines. A number of applications of such metamaterials are discussed, including peculiar lenses that can overcome the diffraction limit and small antennas for emerging wireless communication applications.

  1. Consumo de Benzodiazepinas em Portugal

    OpenAIRE

    Guedes, José Manuel Fraga Santos

    2008-01-01

    Monografia apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em Ciências Farmacêuticas Portugal apresenta dos maiores níveis de utilização de benzodiazepinas ao nível europeu. Este facto veio realçado no relatório da Organização Internacional de Controlo de Estupefacientes e confirmado por indicadores do Instituto Nacional da Farmácia e do Medicamento (INFARMED). É deste modo importante analisar a prática actual no que concern...

  2. Dermatite multifatorial em um canino

    OpenAIRE

    C.B. Matos; Madrid, I.M.; SANTIN,R.; Azambuja,R.H.; I. Schuch; M.C.A. Meireles; M.B. Cleff

    2012-01-01

    Relatou-se um caso clínico de dermatite multifatorial em cão, envolvendo Demodex canis, Sporothrix schenckii e bactérias dos gêneros Staphylococcus e Streptococcus. O animal, macho, da raça Pit Bull, com um ano e três meses de idade, apresentou lesões úmidas, hiperêmicas, descamativas e ulcerativas nas regiões do pescoço e do tórax. Exames laboratoriais confirmaram o diagnóstico de infecção concomitante por fungo, bactéria e parasito. A terapia antimicrobiana com moxidectina, itraconazol e am...

  3. Controlo da Qualidade em Hemoglobinopatias

    OpenAIRE

    Miranda, Armandina

    2015-01-01

    Experiência do Controlo da qualidade em Hemoglobinopatias, pelo Grupo de Trabalho de Hematologia do Programa Nacional de Avaliação Externa da Qualidade (PNAEQ), INSA. As Hemoglobinopatias são doenças monogénicas hereditárias de transmissão autossómica recessiva resultantes de mutações que afetam os genes responsáveis pela síntese das cadeias de globina da hemoglobina, ou as suas regiões regulatórias.

  4. O RACIONALISMO EM DAVID HUME

    OpenAIRE

    da Silva, Lorena Fiungo

    2016-01-01

    Resumo: Para David Hume, o conhecimento humano tem sua origem na experiência. Entretanto, há uma parte deste conhecimento que não tem a mesma origem. Neste caso, para o filósofo, quando um conhecimento não tem sua origem na experiência, ele deriva da imaginação. Este é, precisamente, o caso da matemática, que embora originalmente derivado da experiência, carrega consigo um conhecimento seguro e certo. Nesse sentido, o presente estudo tem por objetivo expor a teoria do conhecimento em David Hu...

  5. Conceito de liberdade em Vigotski

    Directory of Open Access Journals (Sweden)

    Gisele Toassa

    Full Text Available Este texto sintetiza os fundamentos do conceito de liberdade vigotskiano, procurando elucidar suas conexões a partir das investigações do autor sobre linguagem, vontade, funções psíquicas superiores, pensamento e imaginação. Discutem-se, ainda, os antecedentes filosóficos presentes no seu conceito de liberdade e se esboça uma análise das condições concretas necessárias para a livre-escolha em tempos de alienação.

  6. Escalabilidade em servidores cache WWW

    OpenAIRE

    1999-01-01

    O grande crescimento em popularidade da World Wide Web tem motivado várias pesquisas com o objetivo de reduzir a latência observada pelos usuários. Os servidores cache têm-se mostrado uma ferramenta muito importante na busca desse objetivo. Embora a utilização de servidores cache tenha contribuído para diminuir o tráfego na Internet, as estratégias de cooperação utilizadas na composição de grupos (clusters) de caches normalmentetrazem uma degradação de desempenho aos servidores não sendo, por...

  7. Ética em geriatria

    OpenAIRE

    Vasconcelos, Maria Inês Arede Chaves de

    2014-01-01

    Trabalho final de mestrado integrado em Medicina (Geriatria), apresentado á Faculdade de Medicina da Universidade de Coimbra Introdução: Devido às actuais tendências demográficas, os médicos lidam cada vez mais com o doente idoso, cujos problemas médicos e psicossociais complexos (e dos quais muitas vezes resulta perda de autonomia) podem levar ao desenvolvimento de dilemas éticos. Há, desta forma, uma necessidade crescente de os profissionais de saúde estarem familiarizados co...

  8. A melancolia em Al Berto

    OpenAIRE

    Camila Emanuele Martins de Souza

    2015-01-01

    Este trabalho objetiva estudar, sob a perspectiva da melancolia, os livros Salsugem (1984) e Horto de Incêndio (1997), de Al Berto. O autor português produz escritos em que a temática da melancolia atravessa a palavra, o que justifica o debruçar-se sobre as construções textuais da poética albertiana, a fim de traçar-lhe novas possibilidades de leitura por esse ângulo. Para isso, com o intuito de compreender o discurso melancólico segue-se o embasamento teórico: de Klibansky, Panosfsky e Saxl ...

  9. Uma arquitetura para otimização do acesso em redes em malha sem fio

    OpenAIRE

    2008-01-01

    Redes em malha sem fio (wireless mesh networks) são redes dinamicamente auto-organizadas e auto-configuráveis cujos nós automaticamente estabelecem e mantêm a conectividade entre eles. As redes em malha sem fio possuem três tipos de nós: clientes, roteadores e gateways. Os roteadores e os gateways têm pouca ou nenhuma mobilidade. Os roteadores formam a espinha dorsal (backbone) das redes em malha sem fio. A comunicação em uma rede em malha sem fio é multi-salto (multi-hop), e as funcionalidad...

  10. Chemical Composition and Biological Activities of the Essential Oils from <em>Duguetia lanceolataem> St. Hil. Barks

    Directory of Open Access Journals (Sweden)

    Maria A. C. Kaplan

    2012-09-01

    Full Text Available Essential oils of <em>Duguetia lanceolataem> barks, obtained at 2 (T2 and 4 h (T4, were identified by gas chromatography and gas chromatography/mass spectrometry. β-Elemene (12.7 and 14.9%, caryophyllene oxide (12.4 and 10.7% and β-selinene (8.4 and 10.4% were the most abundant components in T2 and T4, respectively. The essential oils inhibited the growth of <em>Staphylococcus aureusem>,> Streptococcus pyogenesem>, <em>Escherichia coliem> and <em>Candida albicansem>. The essential oils were cytotoxic against brine shrimp. The extraction time influenced the chemical composition and biological activities of essential oils obtained from the barks of <em>D. lanceolataem>.

  11. EMS provider determinations of necessity for transport and reimbursement for EMS response, medical care, and transport: combined resource document for the National Association of EMS Physicians position statements.

    Science.gov (United States)

    Millin, Michael G; Brown, Lawrence H; Schwartz, Brian

    2011-01-01

    With increasing demands for emergency medical services (EMS), many EMS jurisdictions are utilizing EMS provider-initiated nontransport policies as a method to offload potentially nonemergent patients from the EMS system. EMS provider determination of medical necessity, resulting in nontransport of patients, has the potential to avert unnecessary emergency department visits. However, EMS systems that utilize these policies must have additional education for the providers, a quality improvement process, and active physician oversight. In addition, EMS provider determination of nontransport for a specific situation should be supported by evidence in the peer-reviewed literature that the practice is safe. Further, EMS systems that do not utilize these programs should not be financially penalized. Payment for EMS services should be based on the prudent layperson standard. EMS systems that do utilize nontransport policies should be appropriately reimbursed, as this represents potential cost savings to the health care system.

  12. Crescimento foliar em arvores e crescimento inicial em plantulas de Kielmeyera coriacea

    OpenAIRE

    Felicio Ryoji Arasaki

    1993-01-01

    Resumo: Neste trabalho foi investigado o crescimento lento que ocorre na parte aérea de Kielmevera coriacea, característica esta que parece ser comum em espécies perenes dos cerrados. O estudo foi realizado em plântulas mantidas em casa de vegetação (UNICAMP) e em câmara de crescimento (Universidade de Edinburgo), assim como em árvores no campo (região de cerrado no município de Itirapina, SP). Os dados de TCR obtidos em plântulas mantidas em condições de casa de vegetação apresentaram valore...

  13. Aprendizagem em contexto: o trabalho de projeto

    OpenAIRE

    Castro, Maria Graciosa dos Reis Martins de

    2013-01-01

    Mestrado em Ensino de Inglês e Francês ou Espanhol no Ensino Básico Relatório final de Estágio submetido como requisito parcial para obtenção do grau de Mestre em ensino de inglês e francês no ensino básico

  14. OCCURENCE OF Salmonella IN CHICKEN CARCASSES AND CUTS COMMERCIALIZED IN GOIÂNIA-GO OCORRÊNCIA DE Salmonella EM CARCAÇAS E CORTES DE FRANGOS COMERCIALIZADOS EM GOIÂNIA-GO

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    Iolanda Aparecida Nunes

    2007-09-01

    Full Text Available

    Its was analised 53 chicken carcasses and commercial cuts acquired in supermarkets of Goiânia-GO aiming to isolate <em>Salmonella>. The contamination rate was 13.2% and serotypes <em>S. brandenburgem>, <em>S. typhimuriumem>, <em>S. agonaem>, <em>S. derbyem> and <em>S. hadorem> were identified.

    KEY-WORDS: <em>Salmonella>; chicken; chicken carcasses; commercial cuts.

    No presente estudo foram analisadas, com vistas ao isolamento de <em>Salmonella>, 53 amostras de carcaças e cortes comerciais de frangos colhidas em supermercados e casas de carnes de Goiânia - GO. Observou-se freqüência média do patógeno de 13,2%, sendo identificados os sorotipos <em>E. brandenburgem>, <em>S. typhimuriumem>, <em>S.> <em>agona>, <em>S. derbyem> e <em>S. Hadarem>.

    PALAVRAS-CHAVE: <em>Salmonella>; frango de corte; carcaça; cortes comerciais.

  15. The determination of total cGMP levels in rod outer segments from intact toad photoreceptors in response to light superimposed on background and to consecutive flashes: a second light flash accelerates the dark recovery rate of cGMP levels in control media, but not in Na(+)-free, low Ca2+ medium.

    Science.gov (United States)

    Cohen, A I; Blazynski, C

    1993-01-01

    In previous experiments we established that a light flash reduced cGMP levels of toad rod outer segments within the transduction time interval, but that recovery of the dark level of cGMP occurred more slowly than reported electrophysiological recovery of membrane potential. We now report that a second light flash accelerates the recovery rate of total cGMP following an initial flash, but that this acceleration is blocked in a medium which is both sodium and calcium deficient. We also noted that calcium deficiency only elevated cGMP levels when sodium was present. For other experiments, we recorded ERG or aspartate isolated PIII responses from eyecups or retinas mounted on our quick-freeze apparatus, the light stimuli originating from the double light-bench of the latter. Whereas background illumination depressed cGMP, no detectable further cGMP loss accompanied the electrical response to a flash superimposed on the background.

  16. Dois funcionalistas franceses em confronto

    Directory of Open Access Journals (Sweden)

    Rafael Eugenio Hoyos-Andrade

    2001-02-01

    Full Text Available

    Comparamos, neste artigo, de modo aproximativo e provisório, dois modelos de análise sintática e dois métodos de representação gráfica dessas análises: trata-se dos modelos e métodos de André Martinet e Lucien Tesnière. Depois de algumas considerações introdutórias relativas ao funcionalismo dos autores em causa, arrolamos um conjunto de características que aproximam ou opõem os seus respectivos modelos. Apresentamos, em seguida, no intuito de beneficiar os estudantes universitários de sintaxe, as representações gráficas de um mesmo enunciado segundo o método estemático de Tesnière e segundo o método de visualização das relações sintáticas de Martinet, para concluir que os dois modelos/métodos, embora diferentes, poderiam eventualmente ser integrados num único sistema de análise e representação.

  17. Metodologia de minienxertia em maracujazeiros

    Directory of Open Access Journals (Sweden)

    Rodrigo Sobreira Alexandre

    2013-03-01

    Full Text Available O objetivo foi avaliar a metodologia de enxertia pela modalidade garfagem no topo hipocotiledonar em fenda cheia, utilizando miniestacas adultas de segmentos apicais de P. edulis f. flavicarpa, P. edulis, P. alata, P. mucronata e P. foetida e internodais de P. mucronata. O experimento foi conduzido em casa de vegetação equipada com sistema de irrigação com nebulização intermitente, do Centro Universitário Norte do Espírito Santo (CEUNES, da Universidade Federal do Espírito Santo (UFES. Os índices de pegamento nas combinações de P. edulis f. flavicarpa/P. edulis f. flavicarpa, P. edulis/P. edulis f. flavicarpa, P. alata/P. edulis f. flavicarpa, P. mucronata/P. edulis f. flavicarpa, P. foetida/P. edulis f. flavicarpa foram de 90; 90; 68; 80 e 90, respectivamente. A metodologia empregada é uma nova opção de enxertia para essas espécies do gênero Passiflora.

  18. Laddering em pesquisa de marketing

    Directory of Open Access Journals (Sweden)

    Tânia Modesto Veludo-de-Oliveira

    Full Text Available O artigo discute a técnica de pesquisa laddering em marketing, considerando a proposta de renovação de conhecimentos sobre metodologia na área. Para isso investiga diversos estudos, artigos e pesquisas que tratam do assunto em nível nacional e internacional. O conceito de cadeias meios-fins é abordado pela estrutura teórica que fundamenta a técnica, ligando atributos, conseqüências percebidas do consumo e valores pessoais relativos a um produto. O artigo segue com a explicação dos procedimentos de campo, como a entrevista e a análise dos dados. A laddering é um instrumento de pesquisa qualitativa bastante útil e poderoso, mas ainda pouco utilizado tanto por acadêmicos como por profissionais de mercado, no Brasil, provavelmente por desconhecimento e pouca divulgação. Cabe, portanto, uma maior disseminação de seu uso.

  19. Analgesia regional em cuidados intensivos

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    Luísa Guedes

    2012-10-01

    Full Text Available JUSTIFICATIVAS E OBJETIVOS: A analgesia regional desempenha um papel importante na abordagem multimodal da dor no doente crítico e permite amenizar o desconforto do doente e reduzir os estresses fisiológico e psicológico associados. Ao diminuir as doses de opioides sistêmicos, reduz alguns dos seus efeitos colaterais, como a síndrome de abstinência, possíveis alterações psicológicas e disfunção gastrintestinal. Apesar desses benefícios, seu uso é controverso, uma vez que os doentes em unidades de cuidados intensivos apresentam frequentemente contraindicações, como coagulopatia, instabilidade hemodinâmica e dificuldade na avaliação neurológica e na execução da técnica regional. CONTEÚDO: Os autores apresentam uma revisão sobre analgesia regional em cuidados intensivos, com foco nas principais vantagens e limitações de seu uso no doente crítico, e descrevem as técnicas regionais mais usadas e a sua aplicabilidade nesse contexto.

  20. Dualismos em duelo Dueling dualism

    Directory of Open Access Journals (Sweden)

    Anne Fausto-Sterling

    2002-01-01

    Full Text Available Os modos europeus e norte-americanos de entender como funciona o mundo dependem em grande parte do uso de dualismos - pares de conceitos, objetos ou sistemas de crenças opostos. Este ensaio enquadra especialmente três deles: sexo/gênero, natureza/criação e real/construído. Embora este texto verse sobre gênero, discuto regularmente o modo como as idéias de raça e gênero surgem a partir de supostos subjacentes sobre a natureza física do corpo. Entender como operam raça e gênero - em conjunto e independentemente - nos ajuda a compreender melhor como o social se torna corporificado.Euro-American ways of understanding how the world works depend heavily on the use of dualisms - pairs of opposing concepts, objects, or belief sytems. This text focuses especially on three of these: sex/gender, nature/nurture, and real/constructed. And although this text focuses on gender, I regularly discuss the ways in which the ideas of both race and gender emerge from underlying assumptions about the body's physical nature. Understanding how race and gender work - together and independently - help us learn more about how the social becomes embodied.

  1. Ser marrano em Minas Colonial

    Directory of Open Access Journals (Sweden)

    Anita Novinsky

    2001-01-01

    Full Text Available Baseado em 57 Processos inéditos de marranos (cristãos-novos, conversos presos em Minas Gerais no século XVIII, este artigo procura mostrar seu papel na Idade de Ouro do Brasil. 64% deles eram mercadores e 23% eram mineiros. Pertenciam à classe média e raros eram os magnatas. Nenhum dele esteve envolvido no tráfico negreiro. Acusados do crime de judaísmo e de pertencerem a sociedades secretas, representaram 42% dos brasileiros condenados à morte. Ser marrano entre os portugueses no Brasil mais um sentimento e uma visão de mundo do que uma prática religiosa.Based on 57 unknown trials of marranos (new christians, conversos arrested by the Inquisition in Minas Gerais in the XVIII the century, this article shows their role in shapping the history of Minas Gerais. 64% of them were merchants na 23% were miners. Most of them belonged to a middle class and rare were those whit great fortunes. No one of them were engaged in slave trade. Acused of judaism and of participating in secret society the marranos of Minas represented 42% of the Brazilian burned at the stake. Being a marrano in Minas Gerais was not always being a crypto-new. Marranism in Brasil was a feeling and a approach to life.

  2. O MAL EM ERIC WEIL

    Directory of Open Access Journals (Sweden)

    Daniel Benevides Soares

    2014-12-01

    Full Text Available O mal ocupa a condição de problema para a filosofia desde a Antiguidade. Passando pelas ponderações dos estóicos e de Santo Agostinho, tratado no contexto da teodiceia por Leibniz, o mal aporta como objeto de preocupação para a moral em Kant. Muito conhecido por sua definição como um kantiano pós-hegeliano, é com Kant, mas indo além dele que Weil trata do mal, pensando-o como formas de violência. Considerada como o outro do sentido e da razão, a violência se manifesta de maneiras variadas. Nosso intuito é determinar o conceito de mal em Eric Weil enquanto forma de violência. Para isso, nos propomos a situar no esquema conceitual da violência duas formas de mal discutidas por Weil nos seus textos: o mal radical e o mal diabólico.

  3. Actinomicose atípica em bovinos

    OpenAIRE

    Bianca Tessele; Andréia Vielmo; Márcia Hammerschmitt; Claudio S.L. Barros

    2014-01-01

    Casos de actinomicose com apresentação atípica são descritos em dois bovinos. Em ambos os casos notou-se uma aumento de volume extenso e duro na maxila. A maxila dos dois bovinos tomou um aspecto de favo de mel como resultado da rarefação destrutiva e da proliferação óssea regenerativa. Na superfície de corte as lesões consistiam de tecido fibroso branco e brilhante em meio ao qual numerosos grânulos amarelos podiam ser vistos. Tratos fistulosos podiam ser demonstrados em meio às lesões. Em c...

  4. 虚拟弧齿锥齿轮齿面可控性椭球抛物面误差的叠加新方法%A New Method Superimposing Controllable Ellipsoid Parabolic Error on Tooth Surface of Virtual Spiral Bevel Gear

    Institute of Scientific and Technical Information of China (English)

    解鹏辉; 王建华; 劳奇成; 吕季轩

    2014-01-01

    为了研究弧齿锥齿轮测量精度稳定性及不同程序测量误差的问题,提出了一种对虚拟弧齿锥齿轮进行可控误差叠加的方法。分析虚拟弧齿锥齿轮建立时产生的误差,在虚拟工件上叠加可控的椭球抛物面误差,调用OpenGL图形库中的函数将叠加误差后的效果进行直观对比。研究结果表明:对虚拟弧齿锥齿轮进行误差可控的叠加,得到了齿面误差可控的虚拟弧齿锥齿轮。%In order to study the stability of measuring precision of spiral bevel gear and measurement error of different process ,a new method of superposition of controllable error on virtual spiral bevel gear is presented .The established error of a virtual spiral bevel gears is analyzed ,the controllable ellipsoid parabolic error is superimposed on the virtual workpiece ,then OpenGL graphics library function is called for comparison with visual effect after the error stacking .The analysis results indicate :A virtual spiral bevel gear with controllable error on tooth surface is obtained by superimposion of controllable error on virtual spiral bevel gear .

  5. Species Differentiation of Chinese <em>Mollitrichosiphum> (Aphididae: Greenideinae Driven by Geographical Isolation and Host Plant Acquirement

    Directory of Open Access Journals (Sweden)

    Gexia Qiao

    2012-08-01

    Full Text Available The impact of both the uplift of the Qinghai-Tibetan Plateau (QTP and the separation of the Taiwan and Hainan Islands on the evolution of the fauna and flora in adjacent regions has been a topic of considerable interest. <em>Mollitrichosiphum> is a polyphagous insect group with a wide range of host plants (14 families and distributions restricted to Southeast Asia. Based on the mitochondrial Cytochrome C Oxidase Subunit I (COI and Cytochrome b (Cytb genes, the nuclear elongation factor-1α (EF-1α gene, and the detailed distribution and host plant data, we investigated the species differentiation modes of the Chinese <em>Mollitrichosiphum> species. Phylogenetic analyses supported the monophyly of <em>Mollitrichosiphum>. The divergence time of <em>Mollitrichosiphum tenuicorpus em>(c>. 11.0 mya (million years ago, <em>Mollitrichosiphum nandiiem> and<em> Mollitrichosiphum montanumem> (<em>c>. 10.6 mya was within the time frame of the uplift of the QTP. Additionally, basal species mainly fed on Fagaceae, while species that fed on multiple plants diverged considerably later. Ancestral state reconstruction suggests that Fagaceae may be the first acquired host, and the acquisition of new hosts and the expansion of host range may have promoted species differentiation within this genus. Overall, it can be concluded that geographical isolation and the expansion of the host plant range may be the main factors driving species differentiation of <em>Mollitrichosiphum>.

  6. Terapia breve em hospital fechado

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    Paulo Cesar Sandler

    1978-09-01

    Full Text Available O presente estudo cuida de pacientes "difíceis" da clínica psiquiátrica e psicoterápica: os pacientes que apresentam o fenômeno da atuação, cuja aproximação terapêutica tem se demonstrado problemática, mesmo com o advento das modernas técnicas de psicoterapia e das comunidades terapêuticas. Os diagnósticos psiquiátricos destes pacientes variam: são neuróticos, apresentam transtornos de pesonalidade, são psicóticos e quase sempre com graves doenças secundárias: alcoolismo e toxicomania (Códigos Classificação Internacional de Doenças 295 a 299, 300. 301, 303 e 304. Propõe-se, à luz da compreensão psicanalítica destas pessoas, um tratamento psicoterápico breve, focal, com o auxílio de uma hospitalização em regime fechado. Para a avaliação dos resultados do método psicoterápico diádico, criaram-se critérios de cura coerentes com a proposta terapêutica, e equiparam-se estes critérios clínicos a valores numéricos. Utilizando 36 pacientes internados, verificou-se até que ponto eles alcançavam estes critérios. Cada paciente recebeu um escore - valor numérico - que expressou o seu desempenho durante o tratamento em regime de internação, e sua conduta pós-alta hospitalar, durante um seguimento médio de 21 meses. Estes 36 pacientes puderam ser divididos em dois grupos: os de evolução favorável (obtivemos 36,1% e os de evolução desfavorável. Por meio de uma amostra sistemática composta por 41 pacientes que não foram submetidos ao método, internados no mesmo período de tempo, no mesmo hospital, e pareados com nossa casuística, fêz-se uma comparação estatística entre os percentis obtidos nas evoluções dos dois grupos. O valor do teste estatístico, o chi quadrado, não foi significante. O exame das proporções correspondentes a cada patologia em separado sugeriu fortemente que o tratamento estaria indicado nas neuroses e nas psicoses, mas que seria realmente ineficaz nos transtornos de

  7. Il ruolo dell'Arvicola delle nevi <em>Chionomys nivalisem> come specie-preda: un'analisi della situazione italiana

    Directory of Open Access Journals (Sweden)

    Armando Nappi

    2003-10-01

    Full Text Available L?Arvicola delle nevi <em>Chionomys nivalisem>, a causa della sua particolare nicchia ecologica costituita, nella sua componente spaziale, dai suoli pietrosi nei cui interstizi vive, viene di norma considerata una preda poco rappresentata nelle catene trofiche. In Italia, eccettuato un dato incerto di cattura da <em>Buteo buteoem>, è risultata predata da cinque specie di serpenti (<em>Coronella austriacaem>, <em>Elaphe longissimaem>, <em>Vipera aspisem>, <em>V. berusem>, <em>V. ursiniiem>, sei di uccelli (<em>Aquila chrysaetosem>, <em>Strix alucoem>, <em>Bubo buboem>, <em>Aegolius funereusem>, <em>Asio otusem> e cinque di mammiferi (<em>Vulpes vulpesem>, <em>Mustela nivalisem>, <em>M. ermineaem>, <em>Martes> sp., <em>Felis catusem>. In alcuni casi, come in <em>Vipera berusem> a Passo Fedaia (BL, <em>Asio otusem> a S. Valentino alla Muta (BZ, <em>Mustela ermineaem> nel Parco Naturale Adamello-Brenta (TN con percentuali piuttosto consistenti, rispettivamente del 69.6%, 60.71% e 35.89%. In uno studio su <em>Vulpes vulpesem> nel Parco Nazionale Gran Paradiso (TO-AO è risultata essere la preda dominante tra i roditori. Sempre nella stessa area, è interessante la predazione da <em>Aegolius funereusem> per la quale risulta, dopo <em>Clethrionomys glareolusem>, la preda più rappresentata (27.97% malgrado, da uno studio di trappolamento di micromammiferi effettuato intorno all?area di nidificazione, risulti assente rivelando così un comportamento esplorativo del rapace diretto proprio alla ricerca dell?arvicola delle nevi. Da una prima analisi sembrerebbe dunque da rivalutare il ruolo di questo roditore come preda, anche considerando il contributo in biomassa che può rappresentare. Su un totale di 184 dati reperiti sulla presenza della specie in Italia, 28 (15.2% derivano da residui di predazione. Benché non risulti un quantitativo alto comparato ad altri micromammiferi è comunque significativo

  8. A Favela posta em Cena

    Directory of Open Access Journals (Sweden)

    Fabiana Valdoski Ribeiro

    2010-08-01

    Full Text Available Em uma realidade de urbanização calcada no aprofundamento dos processos de expropriação e espoliações se consolida o fenômeno da produção de uma morfologia intitulada Favela, que continua a representar um desafio teórico e prático para pesquisadores. Este desafio é enfrentado de várias formas sendo uma delas desenhada no âmbito de duas publicações do Observatório das Favelas (Rio de Janeiro assentadas na busca conceitual do termo favela e objetivando a efetivação de políticas públicas. Esta meta remonta a trajetória deste Observatório que criado em 2001 pensa a inserção da Favela no âmbito das políticas de Estado. A primeira publicação intitulada “Favela: alegria e dor na cidade” (2005 se compõem de quatro capítulos que expõem um movimento da história de formação das favelas na cidade do Rio de Janeiro, as formas de intervenção do Estado, a prática cotidiana dos moradores como manifestação das transgressões diante as opressões e finaliza com as propostas de caminhos possíveis de superação das desigualdades e ampliação da democracia. O argumento central dos autores se direciona para o questionamento das visões de homogeneidade, ausência, carência e apartamento das favelas diante da cidade apontando a urgência de construção de um projeto de cidade democrático e fraterno.Ao longo do texto os autores vão descrevendo os exemplos destas visões e analisa o resultado delas por meio de como a população residente vive, pois são ora invisíveis, ora criminalizados, ora caracterizados enquanto um problema social estabelecendo, portanto, uma lógica autoritária que legitimará no decorrer da história das favelas, as intervenções estatais. Este movimento molda uma linha argumentativa que tenta explicitar o negativo diante a produção possível para o “morar’, que calcado na impossibilidade do acesso à terra pelo imperativo da propriedade privada empurra grandes contingentes populacionais

  9. Fatores associados ao fumo em gestantes avaliadas em cidades brasileiras

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    Kroeff Locimara Ramos

    2004-01-01

    Full Text Available OBJETIVO: Avaliar a correlação dos fatores sociodemográficos e estilo de vida com o hábito de fumar em gestantes atendidas em hospitais. MÉTODOS: O delineamento foi o de um estudo transversal. A amostra foi composta por 5.539 gestantes atendidas em ambulatórios de pré-natal em hospitais públicos credenciados nas cidades de Manaus, Fortaleza, Salvador, Rio de Janeiro, São Paulo e Porto Alegre, entre 1991 e 1995. A seleção foi consecutiva para todas as gestantes com 20 anos ou mais de idade, excetuando-se aquelas com diabetes prévia à gestação. Foram realizadas medidas antropométricas e entrevistas entre a 21ª e a 28ª semanas da gravidez. Por meio de um questionário padronizado, considerou-se como fumante quem informou fumar um ou mais cigarros por dia, como ex-fumante quem informou ter fumado mais de um cigarro por dia e ter cessado, e não fumantes quem informou nunca ter fumado um ou mais cigarros por dia. RESULTADOS: O hábito de fumar na gestação associou-se à baixa escolaridade (RC=2,13; IC 95%: 1,76-2,57 e paridade (RC=1,84; IC 95%: 1,53-2,21. Para o aumento da idade da gestante e uso de bebidas alcóolicas também foram observadas associações positivas com o fumo na gestação. Não foi observada nenhuma associação significativa entre cor da pele e situação ocupacional com fumo na gestação. Um efeito protetor foi observado para mulheres casadas ou com companheiro (RC=0,55; IC 95%: 0,42-0,72. Entre as cidades, tomando Manaus como referência, Porto Alegre apresentou o maior risco para fumo na gestação (RC=5,00; IC 95%: 3,35-7,38, seguida de São Paulo (RC=3,42; IC 95%: 2,25-5,20, Rio de Janeiro (RC=2,53; IC 95%: 1,65-3,88 e Fortaleza (RC=2,56; IC95%: 1,74-3,78. CONCLUSÕES: Os achados são semelhantes àqueles descritos na literatura com relação à escolaridade, paridade e situação conjugal. Entretanto, nenhuma associação com a cor da pele foi observada na análise multivariada. As ex-fumantes mostraram

  10. Alimentazione di <em>Marmota marmotaem> in praterie altimontane delle dolomiti bellunesi

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    Alessandro Rudatis

    2006-03-01

    Full Text Available Abstract The diet of <em>Marmota marmotaem> in the mountain prairie of south-eastern Italian Alps. Diet composition of two family groups of alpine marmots was investigated in two areas of the Agordino’s Dolomites (Italian Alps in June-September 2001, by means of microscopic analysis of faeces and of direct observation of feeding activity. During the whole period of activity, a high consume of Angiosperms was confirmed, especially plants in flower; among them the “graminoids” seemed to play an important role only during the initial part of the active period. Generally vegetative parts predominated over flowers. The ingestion of animal preys was not confirmed by the analysis of droppings. Comparing diet composition of the two groups, Graminaceae (<em>Poa>, <em>Phleum>, Compositae (<em>Achillea>, Cyperaceae/Juncaceae, Leguminosae (<em>Anthyllis>, Rosaceae, and Labiatae (<em>Prunella>, <em>Stachys> formed the bulk of marmot diet in the study areas. Diet showed low diversity considering the abundance of plant species in the surrounding environment. Food resources were probably used in relation to their easy digestibility, with a high content in proteins, sugar and water. The knowledge of vegetation features in relation to marmot trophic habits can represent a useful tool for the management of this species. Riassunto Il regime alimentare di due gruppi di Marmotta alpina è stato studiato in giugno-settembre 2001 in due aree delle Dolomiti agordine (SE Italia, attraverso l’analisi microscopica delle feci e l’osservazione diretta dell’attività alimentare. Durante tutto il periodo di attività si è notato un forte consumo di Angiosperme, specialmente piante a fiore, mentre le ”graminoidi” sembra giochino un ruolo importante all’inizio della stagione. In generale le parti vegetali predominano sui fiori. L’ingestione di prede animali non è stata

  11. Uma pesquisa quase experimental em enfermagem sobre dor em pacientes em coma

    Directory of Open Access Journals (Sweden)

    Gunnar Glauco de Cunto Taets

    Full Text Available RESUMO Objetivo: verificar se pacientes em coma sentem dor durante a intervenção de enfermagem banho no leito. Método: 19 pacientes com 61 ± 17,39 anos de idade participaram do estudo. Realizou-se, pelo método ELISA, a análise quantitativa de substância P (SP na saliva coletada antes e durante o banho no leito. Utilizou-se o programa Graph Pad Prisma 6 para análise dos dados. A verificação da normalidade foi feita pelo teste de Shapiro Wilk que determinou a escolha do teste não paramétrico de Wilcoxon. Resultados: o estudo apresentou aumento estatístico significativo (∆= 5.62%, p<0,001 no nível de SP dos pacientes estudados durante a intervenção de enfermagem. Conclusão: conclui-se que quando cuidamos de pacientes em coma, durante o banho no leito, provocamos ou acrescentamos estímulos dolorosos, logo, eles sentem dor.

  12. Uso de dexmedetomidina em anestesiologia

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    Villela Nivaldo Ribeiro

    2003-01-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A dexmedetomidina é um novo agonista alfa2-adrenérgico que apresenta relação de seletividade entre os receptores alfa2:alfa1 de 1600:1, com importante ação sedativa e analgésica, bom controle hemodinâmico frente ao estresse e que pode produzir, por si só, anestesia. Este agente tem sido empregado para promover analgesia e sedação no período pós-operatório e nas unidades de tratamento intensivo. Devido à suas propriedades, recentemente, a dexmedetomidina passou a ser utilizada também na sala de operações, como fármaco coadjuvante em anestesia. Assim, este artigo faz uma revisão da literatura com relação ao uso da dexmedetomidina na prática anestésica. CONTEÚDO: São apresentados os principais trabalhos com o emprego da dexmedetomidina em Anestesiologia, seja como medicação pré-anestésica, ou durante o ato anestésico-cirúrgico. O mecanismo de ação dos fármacos alfa2-agonistas e as propriedades farmacocinéticas e farmacodinâmicas da dexmedetomidina também são revistos neste artigo. CONCLUSÕES: O uso da dexmedetomidina como medicação pré-anestésica, durante anestesia, ou no período pós-operatório, promove boa estabilidade hemodinâmica. Há redução do consumo de anestésicos durante a anestesia. Os pacientes sedados com a dexmedetomidina podem ser despertados, quando solicitados, e tornarem-se cooperativos. Mesmo doses elevadas do fármaco não provocam depressão respiratória. Bradicardia é um efeito adverso observado com freqüência, problema amenizado pela administração lenta da droga. Assim, a dexmedetomidina torna-se importante recurso adicional para a prática clínica da Anestesiologia, com possibilidade de uso em diversos tipos de pacientes e procedimentos cirúrgicos.

  13. Do Surrealismo em David Lynch

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    Mirian Tavares

    2009-01-01

    Full Text Available O surrealismo, como a arte do seu tempo, propõe uma nova estética, capaz de extrair o belo do absurdo e de instaurar o desvio para que daí surja, de fato, o real. Através da análise de algumas obras de David Lynch e dos livros Les champs magnétiques de Breton e Philippe Soupault e Poisson soluble, de Breton, irei mostrar a pertinência da designação surrealista para a obra do cineasta norte-americano. Lynch, como os surrealistas, constrói uma operação dialética entre o racional/irracional. Ao mesmo tempo em que opera no campo artístico em direção à irracionalidade absoluta, Lynch não nega a sua inserção na sociedade. Acredito que o realizador, como os surrealistas, tenha conseguido encontrar um equilíbrio entre as duas formas de se estar no mundo, racional/irracional, jogando com suas antíteses. O prazer do jogo surrealista consiste em ir até as profundezas do inconsciente e retornar com matéria suficiente para fazer uma obra de arte.Surrealism, as the art of its time, proposes a new aesthetics, one that is able to extract the beautiful from the absurd and to establish the swerve from the standard, from which, in fact, the real comes through. Through the analysis of some works by David Lynch, of Breton and Soupault's Les champs magnétiques, and of Breton's Poisson soluble, I will attempt to show the relevance of the surrealist designation for the work of the American filmmaker. Lynch, like the surrealists, builds a dialectic operation between the rational and the irrational. While operating in the artistic field towards absolute irrationality, Lynch does not deny its role in society. It is my belief that the director, as the surrealists, has managed to find a balance between the two ways of being in the world: rational and irrational; by playing with their antitheses. The pleasure of the surrealist game is to go to the depths of the unconscious and return with sufficient material to make a work of art out of it.

  14. <em>luxS> Mutant Regulation: Quorum Sensing Impairment or Methylation Disorder?

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    Zhengwei Huang

    2012-05-01

    Full Text Available AI-2–mediated quorum sensing has been identified in various bacteria, including both Gram-negative and Gram-positive species, and numerous phenotypes have been reported to be regulated by this mechanism, using the <em>luxS>-mutant strain. But the AI-2 production process confused this regulatory function; some considered this regulation as the result of a metabolic change, which refers to an important metabolic cycle named activated methyl cycle (AMC, caused by<em> luxSem>-mutant simultaneously with the defect of AI-2. Herein we hypothesized that the quorum sensing system—not the metabolic aspect—is responsible for such a regulatory function. In this study, we constructed plasmids infused with<em> sahHem> and induced protein expression in the <em>luxS>-mutant strain to make the quorum-sensing system and metabolic system independent. The biofilm-related genes were investigated by real-time polymerase chain reaction (PCR, and the results demonstrated that the quorum-sensing completed strain restored the gene expression of the defective strain, but the metabolically completed one did not. This evidence supported our hypothesis that the autoinducer-2-mediated, quorum-sensing system, not the AMC, was responsible for <em>luxS> mutant regulation.

  15. Inhibition of <em>Burkholderia multivoransem> Adhesion to Lung Epithelial Cells by Bivalent Lactosides

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    Trinidad Velasco-Torrijos

    2012-08-01

    Full Text Available <em>Burkholderia cepaciaem> complex (Bcc is an opportunistic pathogen in cystic fibrosis patients which is inherently resistant to antimicrobial agents. The mechanisms of attachment and pathogenesis of Bcc, a group of 17 species, are poorly understood. The most commonly identified Bcc species in newly colonised patients,<em> Burkholderia multivoransem>, continues to be acquired from the environment. Development of therapies which can prevent or reduce the risk of colonization on exposure to Bcc in the environment would be a better alternative to antimicrobial agents. Previously, it has been shown that Bcc strains bound to many glycolipid receptors on lung epithelia. Using a real-time PCR method to quantify the levels of binding of <em>B. multivoransem> to the lung epithelial cells, we have examined glycoconjugate derivatives for their potential to inhibit host cell attachment. Bivalent lactosides previously shown to inhibit galectin binding significantly reduced the attachment of <em>B. multivoransem> to CF lung epithelial cells at micromolar concentrations. This was in contrast to monosaccharides and lactose, which were only effective in the millimolar range. Development of glycoconjugate therapies such as these, which inhibit attachment to lung epithelial cells, represent an alternative means of preventing infection with inherently antimicrobially resistant pathogens such as <em>B. multivoransem>.

  16. <em>Emaravirus>: A Novel Genus of Multipartite, Negative Strand RNA Plant Viruses

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    Hans-Peter Mühlbach

    2012-09-01

    Full Text Available Ringspot symptoms in European mountain ash (<em>Sorbus aucupariaem> L., fig mosaic, rose rosette, raspberry leaf blotch, pigeonpea sterility mosaic (<em>Cajanus cajanem> and High Plains disease of maize and wheat were found to be associated with viruses that share several characteristics. They all have single-stranded multipartite RNA genomes of negative orientation. In some cases, double membrane-bound virus-like particles of 80 to 200 nm in diameter were found in infected tissue. Furthermore, at least five of these viruses were shown to be vectored by eriophyid mites. Sequences of <em>European mountain ash ringspot-associated virusem> (EMARaV, <em>Fig mosaic virusem> (FMV, rose rosette virus (RRV, raspberry leaf blotch virus (RLBV, pigeonpea sterility mosaic virus and High Plains virus strongly support their potential phylogenetic relationship. Therefore, after characterization of EMARaV, the novel genus <em>Emaravirus> was established, and FMV was the second virus species assigned to this genus. The recently sequenced RRV and RLBV are supposed to be additional members of this new group of plant RNA viruses.

  17. Delineamentos de Experimentos em Ensaios Fatoriais Utilizados em Preferência Declarada: Uma Aplicação em Benchmarking

    OpenAIRE

    Souza, Osmar Ambrosio de; UNICENTRO

    2009-01-01

    Análise nos delineamentos experimentais em ensaios fatoriais, utilizados em preferência declarada, otimizados pela formação do conjunto de escolha baseado nos arranjos ortogonais de Taguchi e técnicas de blocos incompletos balanceados. Desenvolvimento do processo de estimação dos parâmetros da função logit multinomial que leva em consideração a probabilidade condicional da escolha efetuada no conjunto de escolha formado pela divisão do conjunto de alternativas (modelo LMPC – Logit Multinomial...

  18. Elongation Factor 1β' Gene from <em>Spodoptera exiguaem>: Characterization and Function Identification through RNA Interference

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    Li-Na Zhao

    2012-06-01

    Full Text Available Elongation factor (EF is a key regulation factor for translation in many organisms, including plants, bacteria, fungi, animals and insects. To investigate the nature and function of elongation factor 1β' from <em>Spodoptera> exiguaem> (SeEF-1β', its cDNA was cloned. This contained an open reading frame of 672 nucleotides encoding a protein of 223 amino acids with a predicted molecular weight of 24.04 kDa and pI of 4.53. Northern blotting revealed that <em>SeEF-1β'em> mRNA is expressed in brain, epidermis, fat body, midgut, Malpighian tubules, ovary and tracheae. RT-PCR revealed that <em>SeEF-1β'em> mRNA is expressed at different levels in fat body and whole body during different developmental stages. In RNAi experiments, the survival rate of insects injected with<em> SeEF-1β'em>> em>dsRNA was 58.7% at 36 h after injection, which was significantly lower than three control groups. Other elongation factors and transcription factors were also influenced when EF-1β' was suppressed. The results demonstrate that <em>SeEF-1β' em>is a key gene in transcription in <em>S. exiguaem>.

  19. The use of the antifungal agent miconazole as an inhibitor of Blastocystis hominis growth in Entamoeba histolytica/E. dispar cultures Uso do antifúngico miconazol como inibidor do crescimento de Blastocystis hominis em culturas de Entamoeba histolytica/E. dispar

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    Alessandra Queiroga Gonçalves

    2007-06-01

    Full Text Available In regions with high prevalence, Blastocystis hominis is frequently found in association with Entamoeba histolytica/E. dispar in xenic cultures. Its exacerbated growth is often superimposed on the growth of amebas, thus impeding the continuation of the amebas in the culture, within a few generations. The present study reports on the excellent efficacy (100% of the antifungal agent miconazole in eliminating B. hominis from cultures of E. histolytica/E. dispar, thereby maintaining the integrity of the trophozoites of the amebas. Nystatin presented low efficacy (33.3%.Em regiões de alta prevalência, Blastocystis hominis é freqüentemente encontrado em associação com Entamoeba histolytica/E. dispar em cultivos xênicos. Seu crescimento exacerbado se sobrepõe muitas vezes ao das amebas, impedindo a manutenção destas em cultura, dentro de poucas gerações. O presente estudo relata a excelente eficácia (100% do antifúngico miconazol na eliminação de B. hominis dos cultivos de E. histolytica/E. dispar, mantendo-se a integridade dos trofozoítos das amebas. A nistatina apresentou eficácia baixa (33,3%.

  20. Training for Defense? From Stochastic Traits to Synchrony in Giant Honey Bees (<em>Apis dorsataem>

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    Gerald Kastberger

    2012-08-01

    Full Text Available In Giant Honey Bees, abdomen flipping happens in a variety of contexts. It can be either synchronous or cascaded, such as in the collective defense traits of shimmering and rearing-up, or it can happen as single-agent behavior. Abdomen flipping is also involved in flickering behavior, which occurs regularly under quiescent colony state displaying singular or collective traits, with stochastic, and (semi- synchronized properties. It presumably acts via visual, mechanoceptive, and pheromonal pathways and its goals are still unknown. This study questions whether flickering is preliminary to shimmering which is subject of the <em>fs em>(flickering-shimmering-transition> hypothesis? We tested the respective prediction that trigger sites (<em>ts> at the nest surface (where shimmering waves had been generated show higher flickering activity than the alternative non-trigger sites (<em>nts>. We measured the flickering activity of <em>ts>- and <em>nts>-surface bees from two experimental nests, before and after the colony had been aroused by a dummy wasp. Arousal increased rate and intensity of the flickering activity of both <em>ts>- and <em>nts> cohorts (P < 0.05, whereby the flickering intensity of <em>ts>-bees were higher than that of <em>nts>-bees (P < 0.05. Under arousal, the colonies also increased the number of flickering-active <em>ts>- and <em>nts>-cohorts (P < 0.05. This provides evidence that cohorts which are specialist at launching shimmering waves are found across the quiescent nest zone. It also proves that arousal may reinforce the responsiveness of quiescent curtain bees for participating in shimmering, practically by recruiting additional trigger site bees for expanding repetition of rate and intensity of shimmering waves. This finding confirms the <em>fs-transition> hypothesis and constitutes evidence that flickering is part of a basal colony-intrinsic information system

  1. Effect of Dieckol, a Component of <em>Ecklonia cavaem>, on the Promotion of Hair Growth

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    Sang-Cheol Kim

    2012-05-01

    Full Text Available This study was conducted to evaluate the effect of <em>Ecklonia cavaem>, a marine alga native to Jeju Island in Korea, on the promotion of hair growth. When vibrissa follicles were cultured in the presence of <em>E. cavaem> enzymatic extract (which contains more than 35% of dieckol for 21 days, <em>E. cavaem> enzymatic extract increased hair-fiber length. In addition, after topical application of the 0.5% <em>E. cavaem> enzymatic extract onto the back of C57BL/6 mice, anagen progression of the hair-shaft was induced. The treatment with <em>E. cavaem> enzymatic extract resulted in the proliferation of immortalized vibrissa dermal papilla cells (DPC. Especially, dieckol, among the isolated compounds from the <em>E. cavaem> enzymatic extract, showed activity that increased the proliferation of DPC. When NIH3T3 fibroblasts were treated with the <em>E. cavaem> enzymatic extract and the isolated compounds from the <em>E. cava> enzymatic extract, the <em>E. cavaem> enzymatic extract increased the proliferation of NIH3T3 fibroblasts, but the isolated compounds such as eckol, dieckol, phloroglucinol and triphlorethol-A did not affect the proliferation of NIH3T3 fibroblasts. On the other hand, the <em>E. cavaem> enzymatic extract and dieckol significantly inhibited 5α-reductase activity. These results suggest that dieckol from <em>E. cavaem> can stimulate hair growth by the proliferation of DPC and/or the inhibition of 5α-reductase activity.

  2. EM International, July 1994, Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-10-01

    The Office of Environmental Management (EM) at the Department of Energy (DOE) is seeking out and leveraging foreign technology, data, and resources in keeping with EM`s mandate to protect public health and the environment through the safe and cost-effective remediation of the Department`s nuclear weapons sites. EM works closely with foreign governments, industry, and universities to obtain innovative environmental technologies, scientific and engineering expertise, and operations experience that will support EM`s objectives. Where appropriate, these international resources are used to manage the more urgent risks at our sites, secure a safe workplace, help build consensus on critical issues, and strengthen our technology development program. Through international agreements EM engages in cooperative exchange of information, technology, and individuals. Currently, we are managing agreements with a dozen countries in Europe, Latin America, and Asia. These agreements focus on environmental restoration, waste management, transportation of radioactive wastes, and decontamination and decommissioning. This publication contains the following articles: in situ remediation integrated program; in-situ characterization and inspection of tanks; multimedia environmental pollutant assessment system (MEPAS); LLNL wet oxidation -- AEA technology. Besides these articles, this publication covers: EU activities with Russia; technology transfer activities; and international organization activities.

  3. Hipercalcemia em animais de companhia

    OpenAIRE

    Alves, Sara Duarte de Queirós Moreira

    2014-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária, Ciências Veterinárias A hipercalcemia é definida como um aumento da concentração sérica do cálcio total e/ou do cálcio ionizado, cuja importância está relacionada com o facto de ser um marcador de determinadas doenças. O objetivo deste trabalho foi desenvolver e consolidar os conhecimentos relativos à hipercalcemia nos animais de companhia, nomeadamente no que diz respeito às várias etiologias e à abordagem diagnóstica. A origem da...

  4. MULTIDISCIPLINARIDADE E TRABALHO EM EQUIPE

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    Helmuth Krüger

    2013-10-01

    Full Text Available Foram dois os objetivos deste trabalho: estabelecer critérios para a comparação de pesquisas científicas e analisar alguns problemas psicossociais que podem ocorrer em equipes multiprofissionais. Conclui-se que os critérios de comparação podem ser os quatro componentes de qualquer disciplina científica: o conjunto dos pressupostos filosóficos, o objeto a investigar, a metodologia de pesquisa e a linguagem técnica empregada na elaboração de teorias. Quanto às equipes multiprofissionais, foram analisados 3 problemas: a atribuição de papéis sociais, a confidencialidade das informações e as diferenças de prestígio social entre os membros dessas equipes.

  5. Efeito posterior em dieletricos solidos

    OpenAIRE

    Scarpa, Paulo Cesar do Nascimento

    1989-01-01

    Dissertação (mestrado) - Universidade Federal do Parana Resumo: A macro e a micro-estrutura dos materiais dielétricos são sensíveis a sua historia térmica, mecânica e elétrica. Foi estudada, do ponto de vista teórico e experimental, a teoria da resposta dielétrica de Curie-Schweidler-Gross, vista tanto pela abordagem da teoria de circuito como da teoria de campo. O assunto e visto dentro da teoria geral da relaxação dielétrica, particularmente o efeito posterior em materiais dielétricos só...

  6. HAICAIS EM MANOEL DE BARROS

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    Profª Drª Nery Reiner

    2012-09-01

    Full Text Available O objetivo deste artigo, voltado para a criação poética de Manoel de Barros, é focalizar o conceito da obra de arte como jogo. Escolhemos Manoel de Barros, porque o lúdico, a brincadeira e o humor estão sempre presentes em sua obra. A escolha dos dados, o encaixe de palavras escolhidas a dedo, no eixo paradigmático, formam um caleidoscópio, mostrando novas estruturas, deixando explícito o desejo de brincar com os elementos linguísticos e da natureza. Para este trabalho, escolhemos, para análise, pequenos poemas semelhantes aos haicais japoneses e outros menores ainda, com dois ou até um verso apenas. Contaremos, nesta pesquisa, com a ajuda de teóricos como Johan Huizinga, Ezra Pound, Octavio Paz, Lévi-Strauss, Olga Savary e Alfredo Bosi.

  7. Cuidados paliativos em cuidados intensivos

    OpenAIRE

    Fonseca, Sandrina Fernandes de Andrade

    2012-01-01

    Relatório de prática clínica apresentado à Escola Superior de Saúde Dr. Lopes Dias do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de mestre em Cuidados Paliativos Os cuidados paliativos constituem uma modalidade decorrente da necessidade emergente de melhorar a assistência no fim da vida do doente com doença avançada e incurável e aos seus familiares. Dadas as características complexas das intervenções e às suas articulações conjun...

  8. Sodoma e Gomorra em Pompeios

    OpenAIRE

    Simoes Rodrigues, Nuno

    2012-01-01

    O presente estudo analisa o contexto de uma inscribo encontrada em Pompeios e na qual se leem os nomes das duas cidades bíblicas de Sodoma e Gomorra. Partindo da hipótese de o grafito ter sido escrito antes ou no momento da erup^ao do Vesúvio, considera-se a possibilidade de o seu autor, eventualmente um judeu, ter tido a in¬tenso de relacionar o terramoto de 62 ou a catástrofe de 79 d. C. com a ira divina que na tradi§äo bíblica teria destruido Sodoma e Gomorra This paper studies the cont...

  9. Medidas de democracia em surveys

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    Rose Richard

    2002-01-01

    Full Text Available Este artigo examina como as questões dos surveys sobre democracia são estruturadas de modos diferentes, dependendo do emprego de uma definição idealista ou realista e da presença ou não de comparações com regimes alternativos. Começo mostrando medidas de democracia em países pós-comunistas que perguntam às pessoas se estão satisfeitas ou não com a democracia e pedem que a comparem com um padrão ideal. As seções posteriores apresentam os resultados de questões realistas do New Democracies Barometer, que pedem às pessoas para avaliar regimes do passado, do presente e do futuro - e alternativas não-democráticas historicamente familiares.

  10. Poderes locais em perspectiva comparada

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    Fernando Ruivo

    2012-10-01

    Full Text Available “Os romances não começam como queremos, mas como eles querem”, afirmou Gabriel Garcia Marquez. Similarmente, as nossas vidas nunca decorrem como individualmente as tínhamos pensado, desejado e planeado. Ora, tal como as nossas vidas, também as reformas político-administrativas e as políticas públicas territorializadas não começam, deve dizer-se, como queremos, isto é, como pensámos, desejámos e planeámos, mas em boa parte como elas querem, como se tivessem, afinal, alguma vida própria, a qual...

  11. AFLATOXICOSE EM SUÍNOS

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    Luciana Silveira Flôres Schoenau

    1994-01-01

    Full Text Available RESUMO É descrito um surto de aflatoxicose em suínos Duroc de 2 a 6 meses, que consumiam ração contaminada por 519 ppb de aflatoxinas. A morbidade foi de 97%. A mortalidade foi alta, mas não determinada com exatidão. Os sinais clínicos incluíam recusa do alimento, pouco ganho ou perda de peso, diarreia e icterícia. Lesões subagudas e crônicas foram observadas em 4 porcos necropsiados. Nas lesões subagudas o fígado era escuro, com áreas centrolobulares hemorrágicas deprimidas, havia edema da parede da vesícula biliar e bile viscosa. Nos casos crônicos o fígado apresentava-se firme e amarelo-alaranjado. Havia líquido citrino nas cavidades e edema no cólon espiral. Havia avermelhamento da mucosa gástrica da região fúndica. Alterações subagudas eram necrose e hemorragias centrolobulares, hepatomegalocitose, fibrose e hiperplasia ductal. Nos casos crônicos havia fibrose, hiperplasia ductal, megalocitose e degeneração gordurosa hepatocelular. O diagnóstico de aflatoxicose foi feito baseado nos sinais clínicos, nos achados morfológicos e na presença de níveis significativos de aflatoxina na ração dos porcos (B1 = 484,3ppb, B2 = 110,8ppb, G1 = 343,7ppb e G2 = 99,2ppb. Frangos submetidos à mesma alimentação também desenvolveram lesões da toxicose.

  12. Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge <em>Halichondria em>okadai>

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    Yasuhiro Ozeki

    2012-04-01

    Full Text Available A divalent cation-independent lectin—HOL-18, with cytotoxic activity against leukemia cells, was purified from a demosponge, <em>Halichondria okadaiem>. HOL-18 is a 72 kDa tetrameric lectin that consists of four non-covalently bonded 18 kDa subunits. Hemagglutination activity of the lectin was strongly inhibited by chitotriose (GlcNAcβ1-4GlcNAcβ1-4GlcNAc, fetuin and mucins from porcine stomach and bovine submaxillary gland. Lectin activity was stable at pH 4–12 and temperatures lower than 60 °C. Frontal affinity chromatography with 16 types of pyridylaminated oligosaccharides indicated that the lectin had an affinity for <em>N>-linked complex-type and sphingolipid-type oligosaccharides with <em>N>-acetylated hexosamines and neuramic acid at the non-reducing termini. The lectin killed Jurkat leukemia T cells and K562 erythroleukemia cells in a dose- and carbohydrate-dependent manner.

  13. Técnicas em psicoterapia existencial

    OpenAIRE

    Lima, Vítor André Diaz y Pais Sartóris de

    2014-01-01

    Dissertação de mestrado apresentada ao ISPA - Instituto Universitário Problema: Poucas investigações têm sido feitas ao nível das técnicas em psicoterapia existencial baseada em dados empíricos. A este nível destacam-se apenas os trabalhos de Norcross (1987) e de Alegria et al. (in press). Objetivo: Este estudo procurou perceber quais as práticas existentes em psicoterapia existencial a partir das quais os próprios psicoterapeutas existenciais consideraram ser as mais características do se...

  14. O Trabalho Plurativo em Presidente Prudente

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    Sandro Mauro Guirro

    2011-11-01

    Full Text Available Atualmente, vêm ocorrendo mudanças no campo brasileiro, principalmente nas  propriedades localizadas próximas a malha urbana da cidade. Esse processo se verifica com mais intensidade em cidades como Campinas, Sorocaba, Jundiaí entre outras cidades próximas aos grandes centros urbanos. Em Presidente Prudente, esse processo dá sinais de existência em resposta à crise pela qual vem passando, sobretudo a pequena agricultura. Está-se diante da intensificação das mudanças de funções do trabalho inserido na lavra agrária.

  15. Optimismo e stresse em estudantes de Enfermagem

    OpenAIRE

    Custódio, Susana Margarida Rodrigues; PEREIRA, ANABELA MARIA DE SOUSA; Seco, Graça Maria dos Santos Batista

    2010-01-01

    Comunicação apresentada no XVII Congreso INFAD sobre “Dificultades Sociales y Psicología Positiva de la Vida realizado em Zamora em Abr. 2010. O optimismo é considerado um recurso pessoal que influencia as respostas do indivíduo ao stresse e que contribui para o seu bem-estar. Este estudo quantitativo tem como objectivos avaliar o optimismo dos estudantes e verificar a existência de diferenças em função do sexo e do ano de frequência do curso. Pretende-se ainda analisar a relação entre ...

  16. Mastite em pequenos ruminantes no Brasil

    OpenAIRE

    Peixoto,Rodolfo de M.; Mota, Rinaldo Aparecido; Costa,Mateus M. da

    2010-01-01

    Este artigo objetivou revisar as informações recentes sobre mastite em pequenos ruminantes, abrangendo etiologia, epidemiologia, aspectos de controle e profilaxia. Houve a preocupação em reunir resultados de estudos desenvolvidos no Brasil, uma vez que a mastite tem a interferência de uma série de fatores, como fatores ambientais e outros decorrentes dos sistemas de manejo empregados, condições essas determinantes para etiologia e epidemiologia da enfermidade. A prevalência da mastite em capr...

  17. Otter (<em>Lutra lutraem> presence in Lattari mountains (Campania Region, Southern Italy

    Directory of Open Access Journals (Sweden)

    Roberto Fasano

    1995-12-01

    Full Text Available Abstract A new area of presence of the otter (<em>Lutra lutraem> was found in Campania region (Southern Italy. It included the "Valle delle Ferriere" and "Vècite" canyons close to Amalfi town (Salerno province. A total of 24 sprainting sites was recorded. Riassunto Presenza della lontra (<em>Lutra lutraem> nei monti Lattari (Campania - Si descrive un'area di presenza della lontra (<em>Lutra lutraem> in Campania mai segnalata prima, comprendente la "Valle delle Ferriere" attraversata dal torrente Ceraso e la valle denominata "Vècite" (Amalfi, Provincia di Salerno. In totale sono stati trovati 24 siti di marcamento.

  18. Rendimento de cultivares de tomate para processamento em Goias

    OpenAIRE

    1999-01-01

    Seis ensaios de competição de cultivares de tomate para processamento industrial foram conduzidos nos municípios goianos de Anápolis, Jataí, Porangatú e Santa Isabel, em 1990, e Anápolis e Porangatu, em 1991. O delineamento experimental utilizado foi de blocos casualizados com quatro repetições, tendo as parcelas 80 plantas em 1990 e 70 em 1991. Em Porangatu, em 1990, as plantas foram mais precoces, florescendo 35 e 41 dias após a semeadura e iniciando-se a colheita 38 dias após a antese. Em ...

  19. Feeding habits of the genet <em>Genetta genettaem> in an Iberian continental wetland

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    Maite Sánchez

    2009-02-01

    Full Text Available Abstract This study quantified the diet of the genet <em>Genetta genettaem> in an Iberian continental wetland, the Galachos Nature Reserve, northern Spain, based on the frequency with which items appeared in five monthly-surveyed latrines during 2004-2005. Prey types were identified <em>de visuem> using identification keys and expert advice. the genet was confirmed as an opportunistic and generalist predator, its diet including mammals (95.0%, plants (68.3% and arthropods (60.0% as main prey. With the exception of a newly available prey species, the alien crayfish <em>Procambarus clarkiiem>, the genet probably consumed arthropods because of chance encounters rather than active search. The consumption of fruits and small mammals varied seasonally. Riassunto Alimentazione della genetta <em>Genetta genettaem> in un'area umida continentale della penisola iberica La dieta della genetta è stata investigata in un'area umida interna della Spagna settentrionale, la riserva Naturale dei Galachos. La frequenza di ciascuna categoria alimentare è stata espressa come numero di occorrenze mansili in cinque latrine monitorate per il periodo 2004-2005. Le categorie sono state identificate <em>de visuem> tramite chiavi per il riconoscimento o l'intervento di singoli esperti. I risultati confermano il comportamento alimentare generalista e opportunista della genetta. La dieta ha incluso principalmente mammiferi (95%, vegetali (68.3% e artropodi (60%. Questi ultimi, con l'eccezione del gambero <em>Procambarus clarkiiem>, introdotto e di recente presenza, sono probabilmente utilizzati in modo opportunistico, piuttosto che in seguito a ricerca attiva. L'uso dei frutti e dei micromammiferi varia stagionalmente.

  20. <em>Cassia spectabilis em>(DC Irwin et Barn: A Promising Traditional Herb in Health Improvement

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    Subramanian Deivanai

    2012-08-01

    Full Text Available The genus <em>Cassia>, comprising about 600 species widely distributed worldwide is well known for its diverse biological and pharmacological properties. <em>Cassia spectabilis em>(sin <em>Senna spectabilisem> (DC Irwin et Barn (Fabaceae is widely grown as an ornamental plant in tropical and subtropical areas. <em>C. spectabilis em>has been commonly used in traditional medicine for many years. Information in the biomedical literature has indicated the presence of a variety of medicinally-important chemical constituents in <em>C. spectabilisem>. Pharmacological studies by various groups of investigators have shown that <em>C. spectabilisem> possesses significant biological activity, such as antibacterial, antibiofilm, antifungal and antioxidant properties. Beside this, toxicity studies of this plant have revealed no toxic effect on mice. In view of the immense medicinal importance of <em>C. spectabilisem>, this review aimed at compiling all currently available information on <em>C. spectabilisem>’s botany, phytochemistry, pharmacology, and mechanism of actions, toxicology and its ethnomedicinal uses.

  1. Seasonal effects on the hematology and blood plasma proteins of two species of mice <em>Mus musculus domesticusem> and <em>M. spretusem> (Rodentia: Muridae from Portugal

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    António Mira

    1994-05-01

    Full Text Available Abstract Blood samples were taken from <em>Mus musculus domesticusem> (Rutty, 1772 and <em>M. spretusem> (Lataste, 1883, live-trapped at one month intervals, from September 88 to July 89, in the district of Lisbon, Portugal. The seasonal hematological variations in the commensal species, <em>M. musculus domesticuem>s, were characterized by an increase in red blood cells, hemoglobin and hematocrit values in winter which reverse during summer. On the contrary, in <em>M. spretusem> hematocrit values slightly change throughout the year. In both species the albumin/globulin ratio was low in spring and high in autumn. These results were analysed and discussed taking into account environmental factors and physiological conditions of mice. Riassunto Effetti stagionali sull'ematologia e le proteine del plasma di <em>Mus musculus domesticusem> e <em>M. spretusem> (Rodentia: Muridae in Portogallo - I campioni di sangue provengono da individui di <em>Mus musculus domesticusem> (Rutty, 1772 e <em>M. spretusem> (Lataste, 1883. Gli animali sono stati catturati vivi ogni mese, da settembre 88 a luglio 89, nel distretto di Lisbona, in Portogallo. Le variazioni stagionali ematologiche nella specie commensale, <em>M. m. domesticusem>, sono caratterizzate da un incremento di cellule rosse del sangue, di emoglobina e dei valori di ematocrito in inverno che assumono un andamento opposto in estate. Al contrario, in <em>M. spretusem> i valori di ematocrito non cambiano sensibilmente durante tutto l'anno. In entrambe le specie il rapporto albumina/globulina risulta basso in primavera e alto in autunno. Questi risultati sono stati analizzati e discussi tenendo conto dei fattori ambientali e le condizioni fisiologiche dei topi.

  2. Parasitismo gastrintestinal em diferentes intensidades de pastejo no capim Tânzania, em caprinos

    OpenAIRE

    Silva, Helenara Machado da [UNESP

    2008-01-01

    Os objetivos gerais deste estudo visaram verificar o parasitismo gastrintestinal em diferentes intensidades de pastejo no capim Tanzânia (Panicum maximum (Jacq.) cv. Tanzânia-1), em caprinos e avaliar o método Famacha em cabras ¾ Boer ¼ Saanen e Saanen, criadas em sistema de pastejo, sob condições subtropicais. Foram utilizadas 65 cabras, sendo 21 cabras da raça Saanen e 44 cabras de composição genética ¾ Boer ¼ Saanen, pesando entre 35 a 40 kg. No tratamento de baixa intensidade de pastejo (...

  3. Análise por imagens dos contatos oclusais em boca e em verticulador

    OpenAIRE

    Vieira, Guilherme Campos; Silva, Emerson Hamilton; Lanza,Marcos Dias; Lincoln Dias LANZA; Peixoto, Rogeli Tibúrcio Ribeiro da Cunha; Poletto,Luiz Thadeu de Abreu

    2016-01-01

    A ocorrência de discrepância qualitativa dos pontos de contato da superfície oclusal dos dentes 24 ao 27 foi pesquisada em dois indivíduos, comparando-se imagens digitalizadas obtidas “in vivo” e em modelos montados em verticulador. Seis modelos parciais, obtidos por meio de moldagem de duplo arco, foram montados em um aparelho verticulador. Um dispositivo para obtenção de fotografia intra-oral com a mesma distância focal e mesmo plano foi desenvolvido e confeccionado. Para o registro dos con...

  4. Psicoterapia baseada em evidências em crianças e adolescentes

    OpenAIRE

    Pheula, Gabriel Ferreira; Isolan, Luciano Rassier

    2007-01-01

    CONTEXTO: O termo tratamentos baseados em evidências refere-se a intervenções que possuem evidência de eficácia em pesquisas empíricas. Tratamentos psicológicos baseados em evidências têm sido identificados como um objetivo principal nos Estados Unidos, e, atualmente, há uma clara orientação em direção à sua indicação para os transtornos psiquiátricos mais prevalentes. OBJETIVO: Revisar a efetividade de intervenções psicossociais para as principais formas clínicas dos transtornos mentais na i...

  5. Synthesis and Sensory Evaluation of <em>ent>-Kaurane Diterpene Glycosides

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    Venkata Sai Prakash Chaturvedula

    2012-07-01

    Full Text Available Catalytic hydrogenation of the three <em>ent>-kaurane diterpene glycosides isolated from <em>Stevia rebaudianaem>, namely rubusoside, stevioside, and rebaudioside-A has been carried out using Pd(OH2 and their corresponding dihydro derivatives have been isolated as the products. Synthesis of reduced steviol glycosides was performed using straightforward chemistry and their structures were characterized on the basis of 1D and 2D NMR spectral data and chemical studies. Also, we report herewith the sensory evaluation of all the reduced compounds against their corresponding original steviol glycosides and sucrose for the sweetness property of these molecules.

  6. Probióticos em avicultura

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    Gil de los Santos João Rodrigo

    2005-01-01

    Full Text Available Durante os últimos anos, o incremento de toxinfecções alimentares em humanos pela ingestão de produtos avícolas contaminados com bactérias, sugeriu que produtos oriundos de aves portadoras dessas bactérias podem veiculá-las ao consumidor, provocando doenças entéricas em humanos. Essas observações e a restrição, por parte do mercado consumidor, ao uso de antimicrobianos na produção animal, aumentaram o interesse mundial pelos probióticos e, conseqüentemente, o número de pesquisas realizadas. Esta revisão mostra os avanços e a situação em que se encontram os probióticos em relação à indústria avícola.

  7. A instrucao pelo riso em Santo Agostinho

    National Research Council Canada - National Science Library

    Medeiros, Marcia Maria

    2010-01-01

    Santo Agostinho autor de varias obras, entre elas a que originou este artigo, intitulada A instrucao aos Catecumenos, e referenda partindo do pressuposto de que o ser humano esta em peregrinacao nesse...

  8. Analgesia em modelo animal superior para ortopedia

    OpenAIRE

    Oliveira MT, Maria Teresa; Potes, José Alberto; Queiroga, Cristina; Castro, José António; Pereira, Alfredo; Reis, Joana

    2015-01-01

    O teste de novos biomateriais para aplicações clínicas em ortopedia, ou noutras áreas da medicina, em modelos animais vivos e sencientes, em prol do benefício humano, deve ser objecto de planeamento cuidado e ponderado, dado o conflito ético que se coloca. Compete-nos a nós, enquanto investigadores, garantir que as condições de vida, saúde e bem-estar são asseguradas. O uso de ovinos como modelo superior pré-clínico, para investigação em Ortopedia, tem-se evidenciado devido às suas caracterís...

  9. Platelet-Activating Factor (PAF Antagonistic Activity of a New Biflavonoid from <em>Garcinia nervosaem> var. <em>pubescens> King

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    Azura Abdul Ghani

    2012-09-01

    Full Text Available The methanol extract of the leaves of <em>Garcinia nervosaem> var. <em>pubescens> King, which showed strong inhibitory effects on platelet-activating factor (PAF receptor binding, was subjected to bioassay-guided isolation to obtain a new biflavonoid, II-3,I-5, II-5,II-7,I-4',II-4'-hexahydroxy-(I-3,II-8-flavonylflavanonol together with two known flavonoids, 6-methyl-4'-methoxyflavone and acacetin. The structures of the compounds were elucidated by spectroscopic methods. The compounds were evaluated for their ability to inhibit PAF receptor binding to rabbit platelets using 3H-PAF as a ligand. The biflavonoid and acacetin showed strong inhibition with IC50 values of 28.0 and 20.4 µM, respectively. The results suggest that these compounds could be responsible for the strong PAF antagonistic activity of the plant.

  10. ESPECIFICANDO FORMALMENTE TOPOLOGIAS PARA REDES EM CHIP

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    Eliselma Vieira dos Santos

    2012-03-01

    Full Text Available Este artigo trata da utilização de métodos formais na especificação de topologias para redes em chip. As redes em chip apresentam similaridades com as redes tradicionais, entretanto, por estarem inseridas em sistemas embarcados apresentam características mais restritivas do ponto de vista de espaço, consumo de energia e latência. A topologia descreve o fluxo de dados através da rede e a estrutura física de como os dispositivos estão conectados, bem como, pode determinar o grau de escalabilidade e o desempenho de um sistema como todo. Este artigo apresenta especificações de topologias de redes em chip, relevantes para o projeto de sistemas embarcados, as quais poderão ser utilizadas no processo de síntese de alto nível.

  11. Feocromocitoma em criança

    OpenAIRE

    Herdy,Gesmar Volga Haddad; Olivaes,Maria Cecília; Lopes,Vânia Glória Silami; Pontes,Carlos Adriano Gazanego; Ormond Filho,João Batista; Fonseca,Eliene C.

    2005-01-01

    Feocromocitoma é uma neoplasia de células cromafins que causa sintomas e sinais decorrentes da libertação de catecolminas e é muito rara em crianças. Relatamos um caso feocromocitoma em criança, com difícil manejo clínico, confirmado também pela anatomia-patológica e curado após a ressecção cirúrgica.

  12. Feeding strategies of <em>Rattus norvegicusem>: a review / Una sintesi di alcuni aspetti della strategia alimentare del ratto <em>Rattus norvegicusem>

    OpenAIRE

    Mara Cagnin

    1987-01-01

    Abstract Some of the most relevant aspects of the feeding behaviour of the rat (<em>Rattus norvegicusem>, Berkenhout, 1769) were examined with particular interest in the data collected on wild rats and in natural environments. The rat is considered as an omnivore and generalist species, but both in the wild and in the laboratory marked individual differences were recorded in food preferences and diet spectrum, which probably allow the natural popula...

  13. <em>Helicobacter pyloriem> Disrupts Host Cell Membranes, Initiating a Repair Response and Cell Proliferation

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    Hsueh-Fen Juan

    2012-08-01

    Full Text Available <em>Helicobacter pyloriem> (<em>H. pyloriem>, the human stomach pathogen, lives on the inner surface of the stomach and causes chronic gastritis, peptic ulcer, and gastric cancer. Plasma membrane repair response is a matter of life and death for human cells against physical and biological damage. We here test the hypothesis that <em>H. pyloriem> also causes plasma membrane disruption injury, and that not only a membrane repair response but also a cell proliferation response are thereby activated. Vacuolating cytotoxin A (VacA and cytotoxin-associated gene A (CagA have been considered to be major <em>H. pyloriem> virulence factors. Gastric cancer cells were infected with <em>H. pyloriem> wild type (vacA+/cagA+, single mutant (ΔvacA or ΔcagA or double mutant (ΔvacA/ΔcagA strains and plasma membrane disruption events and consequent activation of membrane repair components monitored. <em>H. pyloriem> disrupts the host cell plasma membrane, allowing localized dye and extracellular Ca2+ influx. Ca2+-triggered members of the annexin family, A1 and A4, translocate, in response to injury, to the plasma membrane, and cell surface expression of an exocytotic maker of repair, LAMP-2, increases. Additional forms of plasma membrane disruption, unrelated to <em>H.> pylori em>exposure, also promote host cell proliferation. We propose that <em>H. pyloriem> activation of a plasma membrane repair is pro-proliferative. This study might therefore provide new insight into potential mechanisms of <em>H. pyloriem>-induced gastric carcinogenesis.

  14. Historicidade da filosofia em Hegel e Heidegger

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    Christian Iber

    2017-02-01

    Full Text Available Gostaria de discutir, em forma de teses, a temática da historicidade da filosofia em contraste e na sua divergência em Hegel e Heidegger. Diferente do historicismo, que não soluciona o problema da historicidade da filosofia, porque ele dissolve tendencialmente a filosofia na história da filosofia e não coloca em especial a questão da verdade, Hegel e Heidegger desenvolvem uma teoria genuinamente filosófica da história da filosofia do interesse filosófico pela verdade. Esse interesse genuinamente filosófico pela verdade segue do seu conceito respectivo de filosofia, que inclui em ambos uma posição crítica à Modernidade. Ambos os pensadores não são apenas pensadores modernos, mas também pensadores críticos da Modernidade, de uma Modernidade que entrou no estado de uma autorreflexão. Em Hegel e Heidegger, a filosofia da história da filosofia é ao mesmo tempo a chave para uma filosofia crítica de Modernidade da história.

  15. Em busca do dossel sagrado

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    Rodrigo Portella

    2009-05-01

    Full Text Available O objetivo deste artigo é apresentar algumas teorias de base sociológica que possam explicar o surgimento, em nossa época, de movimentos eclesiais católicos de cunho tradicional, que resgatam estilos de vida religiosa identificados com o passado, ou melhor, com características de uma igreja anterior ao Concílio Vaticano II. A tese central, ainda que como conclusão provisória, é que, num mundo fragmentado e secularizado, pessoas, especialmente jovens, buscam orientação de vida e fé em formas religiosas identificadas com o passado, pois estas ofereceriam segurança e proteção diante de uma sociedade e igreja cada vez mais secularizadas e sem um dossel sagrado determiná-las. Assim, analisamos a tendência pósmoderna de se voltar a costumes, liturgias e doutrinas mais rígidas ou conservadoras, justa e paradoxalmente no intuito de resistir à pós-modernidade ou à racionalidade moderna. Nosso estudo tem como pano de fundo o movimento da Toca de Assis e, até certo ponto, as teorias sociológicas de Peter Berger. Assim, a metodologia deste estudo é a sociológica.Palavras-chave: Igreja Católica; Jovens; Movimentos eclesiais.ABSTRACTThis article aims to present some sociological theories that can explain the present emergence of Catholic ecclesiastical movements of a “traditional” nature, which rescue religious life styles identified with the past, that is, with the Church before Vatican Council II. The central thesis, though inconclusive, is that, in a fragmented and secularized world, people, especially the young, would search for life guidance and faith in religious forms identified with the past, as they would offer security and protection in a society and in a church rendered more and more secular, and deprived of a sacred canopy to define them. Thus, it analyzes the post-modern trend to return to more rigid or conservative habits, liturgies and doctrines, precisely – and paradoxically – as a form of resistance to post

  16. Net Energy, CO2 Emission and Land-Based Cost-Benefit Analyses of <em>Jatropha> em>Biodiesel: A Case Study of the Panzhihua Region of Sichuan Province in China

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    Xiangzheng Deng

    2012-06-01

    Full Text Available Bioenergy is currently regarded as a renewable energy source with a high growth potential. Forest-based biodiesel, with the significant advantage of not competing with grain production on cultivated land, has been considered as a promising substitute for diesel fuel by many countries, including China. Consequently, extracting biodiesel from <em>Jatropha> curcasem> has become a growing industry. However, many key issues related to the development of this industry are still not fully resolved and the prospects for this industry are complicated. The aim of this paper is to evaluate the net energy, CO2 emission, and cost efficiency of <em>Jatropha> biodiesel as a substitute fuel in China to help resolve some of the key issues by studying data from this region of China that is well suited to growing <em>Jatropha>. Our results show that: (1 <em>Jatropha> biodiesel is preferable for global warming mitigation over diesel fuel in terms of the carbon sink during <em>Jatropha> tree growth. (2 The net energy yield of <em>Jatropha> biodiesel is much lower than that of fossil fuel, induced by the high energy consumption during <em>Jatropha> plantation establishment and the conversion from seed oil to diesel fuel step. Therefore, the energy efficiencies of the production of <em>Jatropha> and its conversion to biodiesel need to be improved. (3 Due to current low profit and high risk in the study area, farmers have little incentive to continue or increase <em>Jatropha> production. (4 It is necessary to provide more subsidies and preferential policies for <em>Jatropha> plantations if this industry is to grow. It is also necessary for local government to set realistic objectives and make rational plans to choose proper sites for <em>Jatropha> biodiesel development and the work reported here should assist that effort. Future research focused on breading high-yield varieties, development of efficient field

  17. Morphometry and morphology of <em>Crocidura> Wagler 1832 (Mammalia, Soricidae in Italy, Sardinia and Sicily, with Fourier descriptors approach: first results / Morfometria e morfologia di <em>Crocidura> Wagler 1832 (Mammalia, Soricidae in Italia, Sardegna e Sicilia, con il metodo dei descrittori di Fourier: primi dati

    Directory of Open Access Journals (Sweden)

    Longino Contoli

    1989-07-01

    Full Text Available Abstract A shape analysis through Fourier descriptors was performed on left mandibles of <em>Crocidura> obtained by Barn Owl pellets from peninsular Italy (Emilia and Liguria districts, Sardinia and Sicily. Thanks to some classical analysis (morphometrical mono- and bidimensional diagrams, morphological analysis and to biogeographical and genetical evidences, the samples of Sardinia, the smaller specimens of Liguria and Emilia and the bigger ones of Emilia were respectively classified, as a working hypothesis, as <em>C. russulaem>, <em>C. suaveolensem> and <em>C. leucodonem>. The "misclassification rate" essay was very low, confirming the reliability of the discrimination rule employed. The sicilian samples, showing an unimodal pattern with respect to all the classical morphometrical characters examined, were then tested against the descriptors of <em>C. russulaem>, <em>C. suaveolensem> and <em>C. leucodonem>. The specimens were assigned to all the above species, with a quite even distribution. On the other hand, the hypothesis of equality of two mean vectors for sicilian samples with <em>C. russulaem> or <em>C. suaveolensem> or <em>C. leucodonem>, tested by Hotelling's T² test, was rejected at 1% significance level. Owing to the fact that the above results seemed quite unexpected in the light of overall bio- geographical knowledges on <em>Crocidura>, the "shape analysis" procedure was repeated, by adding a new "species" for the sicilian samples. The "misclassification rate" essay was very encouraging in the sense of the presence, in Sicily, of a morphological "species", differing from <em>C. russulaem>, <em>C. suaveolensem> and <em>C. leucodonem>, possibly to be referred to <em>C. siculaem> Miller 1901. The euristic value of such up to now first results is discussed. Riassunto L'analisi della forma e l'analisi morfometrica di esemplari di <em>Crocidura> sp. pl. conducono a

  18. Mastites em ruminantes no Brasil

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    Atzel Candido Acosta

    Full Text Available Resumo: A mastite é uma doença complexa e considerada uma das principais causas de perdas à indústria leiteira mundial. Objetivou-se com esta revisão compilar informações dos últimos dez anos sobre a mastite em ruminantes no Brasil. A prevalência da mastite subclínica chega a 48,64% na espécie bovina, 30,7% na espécie caprina, 31,45% na espécie ovina e 42,2% na espécie bubalina, destacando-se a etiologia por Staphylococcus spp. Os fatores de risco associados à ocorrência de mastite estão relacionados a problemas no saneamento ambiental e ao manejo dos animais. As bactérias isoladas do leite mastítico apresentam maior percentual de resistência a penicilina, ampicilina, amoxicilina e neomicina e a utilização de técnicas moleculares no diagnóstico dos agentes causadores de mastites no país, ainda é escassa o que dificulta a obtenção de um diagnóstico mais rápido, sensível e específico.

  19. Actinomicose da Mama em Gestante

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    Mottola Jr Juvenal

    2001-01-01

    Full Text Available A actinomicose mamária é doença inflamatória rara, com poucos casos descritos na literatura. Pode ser primária da mama quando resultante de traumas na pele e papila mamária, e, secundária, quando de origem toracopleural. Sua apresentação clínica é variável, devendo ser diferenciada das doenças mais comuns, dentre elas as mastites e também as neoplasias, como o carcinoma inflamatório. Seu diagnóstico é realizado pela cultura da secreção, com a identificação das colônias de Actinomyces sp. Seu tratamento é a drenagem, quando indicada, a antibioticoterapia endovenosa e manutenção oral por tempo prolongado. Os autores relatam caso de abscesso retromamário por Actinomyces sp. em gestante de 12 semanas que apresentava tumoração mamária expansiva na mama esquerda.

  20. Oficinas da cidade em Fortaleza

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    Cordeiro Andréa Carla de Filgueiras

    2002-01-01

    Full Text Available Este artigo trata do relato de uma experiência de intervenção focal com crianças na cidade de Fortaleza, na qual se procurou, através de discussões em grupo, possibilitar a construção e a re-construção das experiências destes sujeitos na cidade. Partiu-se da premissa que viver hoje na cidade contemporânea requer do sujeito orientação crítica para que ele se situe frente às demandas do viver coletivo. Três momentos de discussão foram focalizados: a reflexão sobre a experiência vivida na cidade; a imaginação sobre as possibilidades deste viver; e a discussão sobre o vivido e o desejado, visando a uma re-construção possível da cidade. As crianças mostraram capacidade de analisar criticamente sua experiência na cidade, apontando os aspectos que, do seu ponto de vista, tornam o viver na cidade particularmente difícil para elas. Mostraram, também, capacidade de indicar caminhos coletivos que suavizariam a tarefa de viver na cidade grande, principalmente quando não se é adulto, e sim criança.

  1. Dermatite multifatorial em um canino

    Directory of Open Access Journals (Sweden)

    C.B. Matos

    2012-12-01

    Full Text Available Relatou-se um caso clínico de dermatite multifatorial em cão, envolvendo Demodex canis, Sporothrix schenckii e bactérias dos gêneros Staphylococcus e Streptococcus. O animal, macho, da raça Pit Bull, com um ano e três meses de idade, apresentou lesões úmidas, hiperêmicas, descamativas e ulcerativas nas regiões do pescoço e do tórax. Exames laboratoriais confirmaram o diagnóstico de infecção concomitante por fungo, bactéria e parasito. A terapia antimicrobiana com moxidectina, itraconazol e amoxicilina foi efetiva, com remissão dos sinais clínicos após 30 dias de tratamento. Este relato salienta a importância do diagnóstico de certeza, que foi determinante para estabelecimento da terapêutica adequada e recuperação do animal.

  2. Burnout em profissionais de bibliotecas

    Directory of Open Access Journals (Sweden)

    Fabiana Neme Nogueira Ramos

    2014-04-01

    Full Text Available O estresse excessivo relacionado ao trabalho, denominado “Burn out”, é descrito como uma síndrome ou conjunto de sintomas resultantes da exaustão e perda de interesse pelo trabalho. O bibliotecário realiza atendimento ao público e atividades técnico-administrativas que incluem tomada de decisões e resolução de conflitos. Este estudo investigou níveis de Burnout de 24 profissionais de bibliotecas de três universidades, que responderam o Inventário Maslach de Burnout (MBI. O estudo consiste também em entrevistas com 10 funcionários de uma das bibliotecas da amostra, para investigar os recursos utilizados como prevenção do estresse e avaliar os recursos e estratégias de enfrentamento, com vistas a compreender os baixos níveis de Burnout encontrados.  Dentre os funcionários que responderam a entrevista, 80% relataram realizar atividades físicas e de lazer fora do ambiente de trabalho. Fatores pessoais, organizacionais e do ambiente de trabalho pareceram atuar positivamente junto à população estudada, prevenindo a instalação do estresse laboral e evitando a exaustão no trabalho.

  3. Monorquidismo em um equino marchador

    Directory of Open Access Journals (Sweden)

    Jéssica Fontana de Magalhães

    2015-06-01

    Full Text Available O monorquidismo é um quadro raramente descrito em equinos, que não apresenta descrições prévias na literatura nacional. Trata-se de um equino adulto brasileiro, com oito anos de idade, sem raça definida, porém com características de raças de origem nacional. Por abordagem inguinal do lado esquerdo, localizou-se a túnica vaginal intacta, que, aberta, continha a cauda de um epidídimo mal formado, o ducto deferente e um delgado pedículo vascular, mas sem indícios de testículo. Exames histológicos e hormonais confirmaram a ausência de tecido testicular. Conclui-se que os exames histológicos e hormonais são essenciais para o diagnóstico de monorquidismo que, apesar de raro, também pode acometer equinos nacionais

  4. Literatura e(m hipertexto

    Directory of Open Access Journals (Sweden)

    Bellei, Sérgio Luiz Prado

    2010-01-01

    Full Text Available A crescente hegemonia do modo de produção digital de textos literários a serem disponibilizados em rede torna urgente o questionamento a respeito das possíveis mudanças que ocorrem na produção de hipertextos eletrônicos a partir de textos literários. O presente ensaio desenvolve uma reflexão crítica sobre o problema a partir de uma distinção do duplo significado de tecnologia enquanto, de um lado, instrumental para a produção de objetos e, de outro, ambiente estruturante que não só produz objetos mas, principalmente, molda os sujeitos que deles fazem uso, reconstituindo no processo hábitos e procedimentos. Se levarmos a sério o conceito de tecnologia enquanto ambiente estruturante, então é bem possível que a literatura traduzida ou produzida diretamente no formato hipertextual sofra modificações profundas quando comparadas à produção literária no meio impresso

  5. Self: um conceito em desenvolvimento

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    Lídia Suzana Rocha de Macedo

    2012-08-01

    Full Text Available Diversas definições de self coexistem nas teorias e práticas psicológicas. Essa variedade é resultante de bases epistemológicas a partir das quais se adotam estratégias diferentes para abordar e demarcar os limites do objeto em questão e descrevê-lo. Este estudo teve como objetivo oferecer uma revisão dos conceitos de self e uma reflexão sobre como esse conceito se articula nas diferentes abordagens teóricas da psicologia. Destaca-se que dilemas centrais à psicologia do desenvolvimento atravessam o conceito de self. Por essa razão, apresenta-se a tese de que, ao analisar cada definição de self, deve-se buscar responder como cada teoria colocou-se diante das dicotomias estabilidade versus transformação, específico versus universal e mundo interno versus mundo externo.

  6. The <em>Chlamydiales> Pangenome Revisited: Structural Stability and Functional Coherence

    Directory of Open Access Journals (Sweden)

    Fotis E. Psomopoulos

    2012-05-01

    Full Text Available The entire publicly available set of 37 genome sequences from the bacterial order <em>Chlamydiales> has been subjected to comparative analysis in order to reveal the salient features of this pangenome and its evolutionary history. Over 2,000 protein families are detected across multiple species, with a distribution consistent to other studied pangenomes. Of these, there are 180 protein families with multiple members, 312 families with exactly 37 members corresponding to core genes, 428 families with peripheral genes with varying taxonomic distribution and finally 1,125 smaller families. The fact that, even for smaller genomes of <em>Chlamydiales>, core genes represent over a quarter of the average protein complement, signifies a certain degree of structural stability, given the wide range of phylogenetic relationships within the group. In addition, the propagation of a corpus of manually curated annotations within the discovered core families reveals key functional properties, reflecting a coherent repertoire of cellular capabilities for <em>Chlamydiales>. We further investigate over 2,000 genes without homologs in the pangenome and discover two new protein sequence domains. Our results, supported by the genome-based phylogeny for this group, are fully consistent with previous analyses and current knowledge, and point to future research directions towards a better understanding of the structural and functional properties of <em>Chlamydiales>.

  7. Antibacterial Secondary Metabolites from the Cave Sponge <em>Xestospongia em>sp.

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    Sridevi Ankisetty

    2012-05-01

    Full Text Available Chemical investigation of the cave sponge <em>Xestospongia em>sp. resulted in the isolation of three new polyacetylenic long chain compounds along with two known metabolites. The structures of the new metabolites were established by NMR and MS analyses. The antibacterial activity of the new metabolites was also evaluated.

  8. Preussianone, a New Flavanone-Chromone Biflavonoid from <em>Garcinia preussiiem> Engl.

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    Gerhard Bringmann

    2012-05-01

    Full Text Available A new flavanone-chromone biflavonoid, preussianone (1, has been isolated from the leaves of <em>Garcinia preussiiem>, along with four known biflavonoids. The absolute stereostructures were elucidated by chemical, spectroscopic, and chiroptical methods. The biological properties of the new biflavonoid against several bacterial strains were evaluated.

  9. Refração por retinoscopia com luz em faixa em cães

    National Research Council Canada - National Science Library

    Ranzani, J.J.T; Mobricci, L.A.L; Carvalho, L.R; Brandão, C.V.S

    2008-01-01

    A refração ocular por retinoscopia com luz em faixa em 10 cães normais, sem raça definida, demonstrou que a maioria dos animais, independentemente do porte, apresentou tendência à hipermetropia...

  10. Antimycobacterial Activity of Constituents from <em>Foeniculum vulgareem> Var. Dulce Grown in Mexico

    Directory of Open Access Journals (Sweden)

    María del Rayo Camacho-Corona

    2012-07-01

    Full Text Available Bioassay guided fractionation of an antimycobacterial extract of <em>Foeniculum vulgareem> var dulce (Apiaceae led to the isolation and characterization of 5-hydroxyfurano-coumarin. The chemical structure of this compound was elucidated by 1H and 13C (1D and 2D Nuclear Magnetic Resonance (NMR spectroscopy. In addition, the active fractions were analyzed by GC-MS and seventy eight compounds were identified; the major compounds were 1,3-benzenediol, 1-methoxycyclohexene, <em>o>-cymene, sorbic acid, 2-hydroxy-3-methyl-2-cyclopenten-1-one, estragole, limonene-10-ol and 3-methyl-2-cyclopenten-1-one. Twenty compounds identified in the active fractions were tested against one sensitive and three MDR strains of <em>Mycobacterium tuberculosis em>using the Alamar Blue microassay. Compounds that showed some degree of antimycobacterial activity against all strains tested were the following: linoleic acid (MIC 100 µg/mL, oleic acid (MIC 100 µg/mL, 1,3-benzenediol (MIC 100–200 µg/mL, undecanal (MIC 50–200 µg/mL, and 2,4-undecadienal (MIC 25–50 µg/mL, the last being the most active compound. To our knowledge, this is the first report of the presence of 5-hydroxy-furanocoumarin in <em>F. vulgareem>.

  11. Home range dynamics of mountain hare (<em>Lepus timidusem> in the Swiss Alps

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    Anne-Sophie Genini-Gamboni

    2009-02-01

    Full Text Available Abstract Little is known on the ecology and behaviour of alpine mountain hare (<em>Lepus timidusem>. Between 1996 and 1997 we analysed by radiotracking the pattern of space use of 8 mountain hares from the Swiss Alps. We estimated home range size using both the kernel density estimator and the minimum convex polygon. We found smaller ranges (38 ha compared to those reported for the species in boreal or arctic habitats, but similar to ranges in Scotland. Hares did not use a centre of major activity (core area and showed high home range overlap, confirming their non-territorial behaviour. Smaller ranges were used during winter compared to the other seasons, whilst no difference in size was found between sexes. Riassunto Dinamica dell'uso dello spazio della lepre bianca (<em>Lepus timidusem> nelle Alpi Svizzere Le informazioni relative all'ecologia e al comportamento della lepre alpina (<em>Lepus timidusem> sono ad oggi scarse. In questo studio abbiamo analizzato l'utilizzo dello spazio di una popolazione di lepre bianca sulle Alpi Svizzere. Tra il 1996 e il 1997 sono stati marcati con redio collare 8 individui di lepre alpina. L'<em>home rangeem> è stato calcolato utilizzando lo stimatore di densità kernel (KDE ed il metodo del minimo poligono convesso (MCP. L'ampiezza degli <em>home rangeem> (38 ha è risultata inferiore a quella riportata per la specie in habitat boreali ed artici. ma simile a quella riscontrata in Scozia. All'interno dell <em>home rangeem> non è stato rilevato alcun centro di maggiore attività (<em>core areaem> ed è stata evidenziata una notevole sovrapposizione tra gli stessi, confermando la non territorialità della specie. Le aree frequentate in inverno sono risultate più piccole rispetto alle altre stagioni e non sono state riscontrate differenze tra i sessi.

  12. Status and conservation of the red squirrel (<em>Sciurus vulgarisem> in Portugal

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    Maria da Luz Mathias

    1998-12-01

    Full Text Available Abstract The historical and recent status and distribution of the red squirrel (<em>Sciurus vulgarisem> in Portugal are analysed using published data, preserved material and unpublished information. In the past the red squirrel occupied the whole of Portugal, but died out towards the end of the 16th century. Now, however, red squirrels have moved back in from Spain and recolonised forests in the north of the country. An important factor limiting the distribution of squirrels in the past was the availability of suitable habitat which provide shelter and food, such as conifer woods. Hunting pressure may also have affected numbers. In Portugal the conservation status of <em>S. vulgarisem> is Rare.

  13. Doenças oculares em neonatos

    Directory of Open Access Journals (Sweden)

    Endriss Daniela

    2002-01-01

    Full Text Available Objetivo: Identificar as principais doenças oculares numa população de neonatos assistidos pelo Sistema Único de Saúde em maternidades de referência no Estado de Pernambuco, orientando o seguimento e tratamento necessário. Métodos: Realizou-se estudo de corte transversal numa população de recém-nascidos em três maternidades públicas, no período de abril a outubro de 2000. Procedeu-se ao exame oftalmológico durante visitas semanais, orientando-se o seguimento e tratamento dos casos com alterações oculares ou fatores de risco. Resultados: Examinaram-se 3280 recém-nascidos: 1403 (42,8% na Maternidade da Encruzilhada (CISAM, 1232 (37,5% na Maternidade do Hospital Barão de Lucena (MHBL e 645 (19,7% na Maternidade do Hospital Agamenon Magalhães (MHAM. 387 eram pré-termo (11,8% dos casos. Encaminharam-se ao serviço especializado 701 neonatos (21,4% do total examinado com alterações oculares ou com fatores de risco. Destes, 46,4% eram pré-têrmo e 37,9% receberam oxigenoterapia, observando-se maior número porcentual na MHBL (45,4%. Observou-se conjuntivite em 3,0% dos olhos, leucocoria em 0,4% e hemorragia subconjuntival em 2,0%. À fundoscopia, encontraram-se hemorragias retinianas em 7,8% dos casos, com acometimento macular em 4,3%. Conclusões: As doenças oculares mais freqüentes foram: hemorragias retinianas e conjuntivites. Os principais fatores de risco observados foram: prematuridade e doenças infecciosas neonatais. Os autores enfatizam que o exame ocular deve ser realizado rotineiramente nos neonatos.

  14. Mobilidade de boro em mudas de pessegueiro

    Directory of Open Access Journals (Sweden)

    Juliana Aparecida de Souza

    2012-09-01

    Full Text Available Recentemente, foi demonstrado que o boro, apresenta rápida e significante mobilidade no floema de algumas espécies produtoras de polióis, que possuem a capacidade de complexar o boro conferindo a esse elemento alguma mobilidade dentro da planta. O trabalho teve por objetivo verificar a mobilidade de boro em mudas de pessegueiro. O experimento foi conduzido em casa de vegetação da UNESP, Ilha Solteira-SP. O delineamento experimental foi em blocos ao acaso, com três repetições, em parcelas subdivididas, conduzido em duas épocas, aos 30 e 60 dias. Foram avaliados nas parcelas cinco tratamentos e nas subparcelas dois tipos de folha: folha velha e folha nova. Os tratamentos estudados foram: sem adubação via solo e foliar com B; sem adubação via solo com B e foliar com 10B; adubação via solo com B e sem adubação foliar; adubação via solo com B e foliar com 10B e adubação via solo com 10B e foliar com B. Foram avaliados a altura, o número de folhas, o teor total de B e a % 10 de B nas folhas velhas e nas folhas novas. Conclui-se que a adubação com boro, em mudas de pessegueiro, proporcionou incremento no número de folhas novas. O teor total de B na folha nova foi maior na adubação com boro via solo que via foliar. Há mobilidade de B aplicado via foliar em mudas de pessegueiro.

  15. X-1A in flight with flight data superimposed

    Science.gov (United States)

    1953-01-01

    This photo of the X-1A includes graphs of the flight data from Maj. Charles E. Yeager's Mach 2.44 flight on December 12, 1953. (This was only a few days short of the 50th anniversary of the Wright brothers' first powered flight.) After reaching Mach 2.44, then the highest speed ever reached by a piloted aircraft, the X-1A tumbled completely out of control. The motions were so violent that Yeager cracked the plastic canopy with his helmet. He finally recovered from a inverted spin and landed on Rogers Dry Lakebed. Among the data shown are Mach number and altitude (the two top graphs). The speed and altitude changes due to the tumble are visible as jagged lines. The third graph from the bottom shows the G-forces on the airplane. During the tumble, these twice reached 8 Gs or 8 times the normal pull of gravity at sea level. (At these G forces, a 200-pound human would, in effect, weigh 1,600 pounds if a scale were placed under him in the direction of the force vector.) Producing these graphs was a slow, difficult process. The raw data from on-board instrumentation recorded on oscillograph film. Human computers then reduced the data and recorded it on data sheets, correcting for such factors as temperature and instrument errors. They used adding machines or slide rules for their calculations, pocket calculators being 20 years in the future. Three second generation Bell Aircraft Corporations X-1s were built, though four were requested. They were the X-1A (48-1384); X-1B (48-1385); X-1C (canceled and never built); X-1D (48-1386). These aircraft were similar to the X-1s, except they were five feet longer, had conventional canopies, and were powered by Reaction Motors, Inc. XLR11-RM-5 rocket engines. The RM-5, like the previous engines, had no throttle and was controlled by igniting one or more of the four thrust chambers at will. The original program outline called for the X-1A and X-1B to be used for dynamic stability and air loads investigations. The X-1D was to be used for heat transfer research while the X-1C was intended as a high-speed armament systems test bed. All of these aircraft like the original X-1s, were launched from a Boeing B-29 or Boeing B-50 'mothership' to take maximum advantage of their limited flying time with a rocket engine. Most launches were made from the JTB-29A (45-21800). The other launch aircraft was EB-50A (46-006). X-1A The Bell X-1A was similar to the Bell X-1, except for having turbo-driven fuel pumps (instead of a system using nitrogen under pressure), a new cockpit canopy, longer fuselage and increased fuel capacity. The X-1A arrived at Edwards Air Force Base, California on January 7, 1953, with the first glide flight being successfully completed by Bell pilot, Jean 'Skip' Ziegler. The airplane also made five powered flights with Ziegler at the controls. The USAF was attempting a Mach 2 flight and USAF test pilot Charles 'Chuck' Yeager was eager. He reached speed of Mach 2.435, at a altitude of 75,000 feet on December 12, 1953, a speed record at the time. But all was not well, the aircraft encountered an inertial coupling phenomenon and went out of control. Once the X-1A had entered the denser atmosphere (35,000 feet) it slowly stabilized and Yeager was able to return to Edwards. The aircraft had experienced high-speed roll-coupling, something aerodynamicists had predicted, but this was the first actual encounter. On August 26, 1954, Major Arthur Murray, USAF test pilot flew the X-1A to an altitude record of 90,440 feet. NACA High-Speed Flight Station received the aircraft in September 1954 and returned it to Bell for the installation of an ejection seat. NACA test pilot Joseph Walker made a familiarization flight on July 20, 1955 followed by another scheduled flight on August 8, 1955. Shortly before launch the X-1A suffered an explosion. The extent of the damage prohibited landing the crippled aircraft. The X-1A was jettisoned into the desert, exploding and burning on impact. Walker and the B-29 crew returned to base in satisfactory condition. Four pilots had completed 29 flights (including aborts). X-1B The Bell Aircraft Corporation X-1B was similar to the Bell X-1A except for the installation of wingtips extensions for its last three flight. The NACA portion of the X-1B flight test program was for the purpose of aerodynamic heating research, accumulating data during 1956-1958. The X-1B was fitted with special instrumentation for exploratory aerodynamic heating tests. It had over 300 thermocouples installed on it. It was the first aircraft to fly with a reaction control system, a prototype of the control system used on the X-15 and other piloted aircraft. Midway through its flight test program, the X-1B was equipped with an Reaction Motors, Inc. XLR-11-RM-9 engine which differed, from the other XLR-11s, only in having an electric spark, low-tension interrupter type ignition in place of the older high-tension type. On January 27, 1959 the X-1B was given to the Air Force Museum at Wright-Patterson Air Force Base, Ohio, for preservation and public display. This aircraft completed a total of 27 glide and powered flights made by eight USAF test pilots and two NACA test pilots. X-1C Following the X-1B was the projected X-1C, which was canceled while still in the mock-up stage. The birth of transonic and supersonic-capable aircraft like the North American F-86 Sabre and the North American F-100 Super Sabre eventually eliminated the need for the X-1C. X-1D The X-1D was the first advanced model of the X-1 family to roll from Bell Aircraft Corporation's plant. It arrived at Edwards, California, in July 1951 suspended from the bomb bay shackles of a Boeing EB-50A, (46-006) aircraft. On July 24, 1951, with Bell test pilot Jean 'Skip' Ziegler at the controls, the X-1D had the only successful flight of its career. It was an unpowered glide flight, and on landing the nose gear failed with the plane sliding to a stop. The aircraft was repaired and ready once more for flight when USAF test pilot Frank 'Pete' Everest boarded the aircraft for launch on August 22, 1951. The drop from the Boeing B-50 was canceled because of mechanical problems. On the way back to the landing field and after the crew had jettisoned the propellants, an explosion occurred with flames being reported by the chase plane pilot. The X-1D was dropped to crash on the desert near the south end of Rogers Dry Lakebed. The second generation Bell Aircraft Corporations X-1s increased man's understanding of the stability and control characteristics, and aerodynamic heating at high-speeds and the environment of high-altitude flight. INVESTIGATION Since there had been a loss of several aircraft during the period of the rocket flights, the NACA instituted an investigation. It sent samples of a suspicious looking oily residue from a liquid oxygen tank to a Los Angeles, California, laboratory and to the chemical laboratory at Edwards Air Force Base, California. The Edwards laboratory identified the substance as TCP--tricresyl phosphate--a substance used to impregnate leather. All the destroyed rocket planes--as well as those still flying--had gaskets made of Ulmer leather. The TCP had been the culprit, because it could easily detonate in the presence of liquid oxygen. Armed with this knowledge, the Air Force and the NACA avoided all future catastrophic blasts.

  16. Delirium superimposed on Charles Bonnet syndrome: a case study.

    Science.gov (United States)

    Yeager, Jennifer J

    2013-01-01

    Older adults with visual impairment may experience visual hallucinations in the setting of normal cognition and absence of psychiatric illness. This phenomenon is referred to as Charles Bonnet syndrome. Information concerning Charles Bonnet syndrome predominantly comes from case studies. Reassuring the person experiencing the hallucinations they are not suffering from psychosis constitutes the mainstay of treatment. What follows is the case of a vision impaired, older adult male with known Charles Bonnet syndrome, who, following emergency surgery and associated delirium while in the intensive care unit, experiences an aggressive change in hallucinations. Nurses need to understand the pathology and characteristics of Charles Bonnet syndrome in order to distinguish it from other pathologies underlying hallucinations. This knowledge is necessary to provide safe, patient-centered care for older adults.

  17. Computer modeling of capillary flow with superimposed pulsations

    Science.gov (United States)

    Yaganova, A. E.; Marfin, E. A.

    2016-11-01

    Increasing efficiency of methods of oil production can be achieved by the influence of elastic vibrations. It is a well-known fact that shift viscosity of oil changes under the effect of elastic vibrations. This change depends on properties of the oil and exposure mode. Existing approaches to the research of the way wave exposure impacts on viscosity are based on measuring it after the processing. This article concerns development of methods to measure viscosity of liquid right during its exposure to elastic vibrations. The suggested approach is based on combining numerical and natural experiments. We investigated the pulsating flow of viscid liquid in a capillary numerically in this article. We received allocations of fields of average velocity and pressure in a capillary. It is demonstrated that imposed pulsations in a capillary do not impact on hydrodynamics of the flow. We offered the scheme of an experimental installation for a research of the impact that wave exposure has on the viscosity of liquids. The installation is based on a capillary viscometer.

  18. Decomposition of Superimposed Waveforms Using the Cross Time Frequency Transform

    Science.gov (United States)

    2007-11-02

    Decomposition of Myoelectric Signals .” IEEE Engineering in Medicine and Biology. (June): pp 24-28. [5] Choi, H.I., Williams, W.J. Improved time...and De Luca, C. J. (1982). “A Procedure for Decomposing the Myoelectric Signal into its Constituent Action Potentials. Part I. Technique, Theory...throughout a muscle contraction. This paper addresses a specific aspect of the identification process: the decomposition of the compound signal

  19. Diagnostic dilemma: osteopetrosis with superimposed rickets causing neonatal hypocalcemia.

    Science.gov (United States)

    Olgaç, Asburçe; Tümer, Leyla; Boyunağa, Öznur; Kızılkaya, Metehan; Hasanoğlu, Alev

    2015-04-01

    Osteopetrosis is a rare genetic condition of reduced osteoclastic bone resorption which causes defective bone remodeling and skeletal sclerosis during growth, having effects on many organs and tissues. Mutation of T-cell immune regulator 1 (TCRG1) gene is the most common genetic defect leading to osteopetrosis, with poor prognosis. The autosomal recessive form presents in the infantile period (also known as malignant infantile osteopetrosis--MIOP), and is characterized by fractures, short stature, hepatosplenomegaly, compressive neuropathies, hypocalcemia and pancytopenia. Being a rare disease with non-specific clinical manifestations, the diagnosis is difficult and usually delayed. Rickets is a characteristic feature of MIOP which results from the defect in osteoclasts to provide a normal Ca/P balance resulting in the poor mineralization of the osteoid. Various treatment options have been suggested for osteopetrosis, but hematopoietic stem cell transplantation still remains the only curative treatment option presently. The authors report the case of a 46-day-old girl with late-onset neonatal hypocalcemia and rickets that was later diagnosed as osteopetrosis. This case report emphasizes that infantile osteopetrosis is an important cause of neonatal hypocalcemia. As irreversible complications develop within the first months of life, immediate diagnosis and early intervention are crucial and may be life-saving.

  20. Superimposed Code Theorectic Analysis of DNA Codes and DNA Computing

    Science.gov (United States)

    2010-03-01

    Bounds for DNA Codes Based on Fibonacci Ensembles of DNA Sequences ”, 2008 IEEE Proceedings of International Symposium on Information Theory, pp. 2292...5, June 2008, pp. 525-34. 32 28. A. Macula, et al., “Random Coding Bounds for DNA Codes Based on Fibonacci Ensembles of DNA Sequences ”, 2008...combinatorial method of bio-memory design and detection that encodes item or process information as numerical sequences represented in DNA. ComDMem is a

  1. Infracommunities of intestinal helminths of the Red Fox <em>Vulpes vulpesem> (Linnaeus, 1758 from Italian Alps

    Directory of Open Access Journals (Sweden)

    Anna Rita Di Cerbo

    2003-10-01

    Full Text Available <em>Vulpes vulpesem> (Linnaeus, 1758 is one of the most common carnivore in Italy and its spread includes almost the whole national territory. The species shows an high ecological plasticity and a variable diet composition connected in part to human sources. This high adaptability permits the red foxes to colonize different habitats like the suburbs of large cities as well as the small villages located in mountain areas. On the other hand, the tourism pressure seems to assume a great importance in the Alps, also in those areas where the foxes live. So, indirect interactions could take place between these animals and the humans. The role of <em>V. vulpesem> in the zoonoses has not to be understated since this carnivore could transmit parasitic diseases that are able to cause serious pathologies in humans. This study aims just to investigate on intestinal communities of helmiths of <em>V. vulpesem> in order to make progress in current knowledge on epidemiological situation in Italian Alps. During 1998-2003, we have examined 450 foxes from Trentino Alto Adige, Veneto, Lombardia and Valle d'Aosta. The specimens collected were found dead or have been hunted (according to national law n. 157/92 in localities situated between 170 and 2200 m a.s.l. The carcasses were carried to the provincial sections of Zooprofilattici Institutes, where the intestine was drawn by each sample and all the material was sent to the Faculty of Veterinary Medicine of Milan. Parasitological examination of the small intestines was performed by the analysis of the whole sediment and counting technique (SCT. Parasites were preserved in alcohol 70° before to be clarified or stained and identified by microscope (Zeiss Axioscop. Mean abundance, mean intensity and prevalence were calculated for each taxon of helminth. Dates of sampling were grouped within the four seasons. Statistic tests were performed with software package SPSS rel. 11.5 and spatial analysis with the

  2. Carrier mobility of highly transparent conductive Al-doped ZnO polycrystalline films deposited by radio-frequency, direct-current, and radio-frequency-superimposed direct-current magnetron sputtering: Grain boundary effect and scattering in the grain bulk

    Science.gov (United States)

    Nomoto, Junichi; Makino, Hisao; Yamamoto, Tetsuya

    2015-01-01

    The effects of using radio-frequency (RF)-superimposed direct-current (DC) magnetron sputtering deposition on the structural, electrical, and optical properties of aluminum-doped ZnO (AZO)-based highly transparent conducting oxide films have been examined. AZO films were deposited on heated non-alkaline glass substrates (200 °C) using ZnO:Al2O3 (2 wt. % Al2O3) ceramic oxide targets with the total power varied from 150 to 300 W, and at various RF to DC power ratios, AZO films deposited by a mixed approach with the RF to the total power ratio of 0.14 showed the lowest resistivity of 2.47 × 10-4 Ω cm with the highest carrier concentration of 6.88 × 1020 cm-3 and the highest Hall mobility (μH) of 36.8 cm2/Vs together with the maximum value of an average transmittance in the visible spectral range from 400 to 700 nm. From the analysis of optical data based on the simple Drude model combined with the Tauc-Lorentz model and the results of Hall effect measurements, the optical mobility (μopt) was determined. A comparison of μopt with μH clarified the effects of the mixed approach not only on the reduction of the grain boundary contribution to the carrier transport but also on retaining high carrier mobility of in-grains for the AZO films.

  3. Fatigue life estimation of welded joints of an aluminium alloy under superimposed random load waves (follow-up report). Effects of high frequency components; Jujo random kajuka ni okeru aluminium gokin yosetsu tsugite no hiro jumyo suitei (zokuho). Koshuha seibun no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, I.; Maenaka, H.; Takada, A. [Ship Research Inst., Tokyo (Japan)

    1996-12-31

    In order to examine fatigue behavior of boxing welded joints of anticorrosion aluminum A 5083 P-O alloy, the residual stress measurements, static loading tests, elastic finite element analyses, constant amplitude fatigue tests, and random fatigue tests were conducted. For a load wave in the random loading fatigue tests, a direct current component, a zero-mean narrow band random process, and a high frequency component were combined and superimposed, to examine the effect of the high frequency component and the effect of the stress cycle count method and the mean stress correction on the life estimation. For the fatigue analysis, a reference stress, such as that considering the structural stress concentration, was proved effective in reducing the amount of scattering in the fatigue test results and in improving the life estimation accuracy. Accordingly, for the actual scale measurements, it is insufficient only to measure the stress at points far from the crack initiation place. It is required to analyze the fatigue by measuring the reference stress same as the basic data acquisition tests in the laboratory. 4 refs., 21 figs., 4 tabs.

  4. Synthesis and Cytotoxicity Evaluation of 13-<em>n>-Alkyl Berberine and Palmatine Analogues as Anticancer Agents

    Directory of Open Access Journals (Sweden)

    Lei Zhang

    2012-09-01

    Full Text Available By introducing long carbon-chain alkyl groups at the C-13 position of berberine and palmatine, 13-<em>n>-hexyl/13-<em>n>-octyl berberine and palmatine chloride analogues 4ad were synthesized and examined by MTT assays for cytotoxic activity in seven human cancer cell lines (7701QGY, SMMC7721, HepG2, CEM, CEM/VCR, KIII, Lewis, yielding IC50 values of 0.02 ± 0.01–13.58 ± 2.84 μM. 13-<em>n>-Octyl palmatine (compound 4d gave the most potent inhibitor activity, with an IC50 of 0.02 ± 0.01 μM for SMMC7721. In all cases, the 13-<em>n>-alkyl berberine and palmatine analogues 4ad were more cytotoxic than berberine and palmatine. In addition, compounds 4ad also exhibited more potent cytotoxicity than berberine and palmatine in mice with S180 sarcoma xenografted<em> in vivoem>. The primary screening results indicated that the 13-<em>n>-hexyl/13-<em>n>-octyl berberine and palmatine analogues might be valuable source for new potent anticancer drug candidates.

  5. Molecular Cloning, Characterization and Expression of the Phenylalanine Ammonia-Lyase Gene from <em>Juglans regiaem>

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    Feng Xu

    2012-06-01

    Full Text Available Phenylalanine ammonia-lyase (PAL is the first key enzyme of the phenypropanoid pathway. A full-length cDNA of <em>PAL> gene was isolated from <em>Juglans regiaem> for the first time, and designated as <em>JrPAL>. The full-length cDNA of the <em>JrPAL> gene contained a 1935bp open reading frame encoding a 645-amino-acid protein with a calculated molecular weight of about 70.4 kD and isoelectric point (pI of 6.7. The deduced JrPAL protein showed high identities with other plant PALs. Molecular modeling of JrPAL showed that the 3D model of JrPAL was similar to that of PAL protein from <em>Petroselinum crispumem> (PcPAL, implying that JrPAL may have similar functions with PcPAL. Phylogenetic tree analysis revealed that JrPAL shared the same evolutionary ancestor of other PALs and had a closer relationship with other angiosperm species. Transcription analysis revealed that <em>JrPAL> was expressed in all tested tissues including roots, stems, and leaves, with the highest transcription level being found in roots. Expression profiling analyses by real-time PCR revealed that <em>JrPAL> expression was induced by a variety of abiotic and biotic stresses, including UV-B, wounding, cold, abscisic acid and salicylic acid.

  6. Mammal prey of the Barn Owl (<em>Tyto albaem> in Parque Luro Reserve, La Pampa, Argentina

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    Sergio Tiranti

    1994-05-01

    Full Text Available Abstract The diet of the barn owl was studied through the analysis of pellets obtained in various sites within the Parque Luro reserve, located in an area of xerophyte Caldén forests. The study of 1241 prey items revealed a high dominance of the cricetid rodents <em>Calomys> sp., <em>Akodon molinaeem> and <em>Eligmodontia typusem>, followed by other 8 species of rodents, one species of marsupial and undetermined birds and anuran amphibians. For comparing the diets from a relatively undisturbed forested area (Parque Luro and a deforested site, two subcollections of pellets were analyzed. Differences in FNB values and in the prevalence and composition of prey assemblages were observed between these areas. Riassunto Mammiferi predati dal Barbagianni (<em>Tyto albaem> nella Riserva Parque Luro, La Pampa, Argentina - La dieta del Barbagianni (<em>Tyto albaem> è stata studiata attraverso l'analisi delle borre ottenute in varie località all'interno della riserva Parque Luro, situata in un'area con boschi xerofili a <em>Prosopis caldeniaem>. Lo studio di 1241 campioni ha rivelato un'elevata prevalenza di roditori cricetidi <em>Calomys> sp., <em>Akodon molinaeem> and <em>Eligmodontia typusem>, seguiti da altre 8 specie di roditori, una specie di marsupiali e uccelli e anfibi anuri indeterminati. Per il confronto delle diete sono state analizzate due sub-raccolte di borre di rapaci provenienti da un'area boscata relativamente indisturbata e da un sito disboscato. In queste aree sono state osservate differenze nei valori della FNB e nella prevalenza e composizione delle prede.

  7. Triagem em saúde mental infantil

    Directory of Open Access Journals (Sweden)

    Fabiana Vieira Gauy

    Full Text Available Este estudo foi conduzido para comparar os resultados de um procedimento grupal aberto e um procedimento individual estruturado para avaliação do comportamento da criança conforme o relato materno. Participaram deste estudo 29 mães que buscavam atendimento para seus filhos em uma unidade de saúde mental infanto-juvenil. As primeiras 15 mães que procuraram o serviço foram entrevistadas individualmente conforme um roteiro estruturado desenvolvido a partir do CBCL e depois foram entrevistadas em grupo, em formato aberto. As outras 14 mães participaram da entrevista grupal aberta e em seguida participaram da entrevista individual estruturada. Os resultados das entrevistas foram comparados tomando como referência as 67 categorias comportamentais identificadas a partir do roteiro individual e quatro variáveis contextuais relatadas nos dois procedimentos. Os resultados mostram que um número substancialmente maior de comportamentos-problema foi identificado através de entrevista individual estruturada do que através de entrevista grupal aberta realizada com os mesmos informantes. É possível que o uso de um roteiro estruturado em entrevistas grupais possa oferecer mais informações com otimização do tempo de avaliação.

  8. O conceito de paranoia em Freud

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    Roberto Calazans

    Full Text Available Neste artigo, refazemos o percurso freudiano a propósito do conceito de paranoia em sua obra. Esse percurso se fará a partir dos textos considerados pré-psicanalíticos, passando por aquele que é considerado o texto maior de Freud sobre as psicoses (o Caso Schereber, culminando com suas análises que levam em consideração sua segunda teoria sobre o funcionamento psíquico e sobre o conflito pulsional. Nosso objetivo é demonstrar como Freud, em sua elaboração das questões relativas à psicose, e à paranoia, mais especificamente, jamais se furtava a encarar os desafios que a clínica impunha. E por não recuar frente a esses desafios é que a sua própria teoria vai se formulando, em uma relação dialética entre os impasses da prática e a necessidade de estabelecer um rigor teórico. O artigo trata, também, da forma como o rigor teórico permite o estabelecimento de um diagnóstico diferencial entre neurose e psicose, além de assentar as bases para que os psicanalistas pós-freudianos pudessem pensar em um direcionamento para tratar a psicose.

  9. Roost selection by barbastelle bats (<em>Barbastella barbastellusem>, Chiroptera: Vespertilionidae in beech woodlands of central Italy

    Directory of Open Access Journals (Sweden)

    Danilo Russo

    2003-10-01

    Full Text Available The barbastelle bat, <em>Barbastella barbastellusem> (Schreber, 1774 is a medium-sized, tree-dwelling vespertilionid classified as ?Endangered? in Italy; in western Europe it may be one of the rarest bat species. <em>B. barbastellusem> shows roosting preferences that should be regarded as a key point in conservation protocols. We examined roost selection in a breeding population of <em>B. barbastellusem> from the Abruzzo Lazio and Molise National Park (central Italy at three levels: woodland structure and management type; tree characteristics; and cavity characteristics. In 2001-2002, we fitted 31 adult <em>B. barbastellusem> (29 lactating females, one pregnant female and one male with 0.48g radio-tags and tracked them to their roost-trees. The bats were tracked for 4.5 ± 3.7 days (range: 0-12 days. We located 33 roosts used by 25 subjects (1.8±1.2 roosts/bat, range 1-5. The bats switched roosts frequently: 13 bats used more than one tree over the study period. A chi-square analysis showed that the roosts were not distributed at random across woodland categories: unmanaged woodland was positively selected, whereas shelterwood-harvested woodland was used in proportion to its availability, and ?pastures+scattered trees? was avoided. Twenty out of 33 roost trees were dead <em>Fagus sylvaticaem> trees; conversely, living <em>F. sylvaticaem> dominated in a tree sample obtained at random; dead trees were used more than expected (Χ² test, <em>P> <0.001. Overall, roost trees were significantly taller and had a larger diameter at breast?s height and more cavities than random trees; they also had a lower percent canopy closure than random trees. To highlight which variables were actually associated with selection, we devised a logistic regression model. The full model was significant (<em>P> <0.001; removal of tree type and tree height affected the model significantly, but the other variables did not produce detectable effects. The

  10. A JUSTIÇA EM TERMOS HUMEANOS

    Directory of Open Access Journals (Sweden)

    Elcio Alcione Cordeiro

    2010-01-01

    Full Text Available Apresento neste breve artigo uma noção de justiça segundo o pensamento de DavidHume. A justiça humeana se posiciona totalmente em prol da ordem social, isto é, o objetivo éque a segurança na sociedade seja instaurada. Para que isso aconteça de fato, é preciso quealgumas regras desta virtude artificial venham a ser respeitada por todos os homens. Ajustificação da propriedade é uma máxima que deve ser assegurada estavelmente. Os homensestão predispostos ao egoísmo que vence a benevolência natural. A partir do momento em queos homens percebem que são egoístas e que viver em sociedade é vantajoso, acrescentam-seentão as convenções para que a ordem social seja instaurada.

  11. Influenza em animais heterotérmicos

    OpenAIRE

    Mancini, Dalva Assunção Portari; Mendonça, Rita Maria Zucatelli; Cianciarullo, Aurora Marques; Kobashi,Leonardo Setsuo; Trindade,Hermínio Gomes; Fernandes, Wilson; Pinto,José Ricardo

    2004-01-01

    O objetivo foi pesquisar Ortomyxovirus em animais heterotérmicos. Coletou-se sangue de serpentes dos gêneros Bothrops e Crotalus e de sapo e rãs dos gêneros Bufo e Rana, para a detecção dos receptores de hemácias e anticorpos específicos, ao vírus influenza, pelos testes de hemaglutinação e inibição da hemaglutinação, respectivamente. Pelo teste de hemaglutinação, verificou-se que serpentes e sapos em cativeiro apresentaram receptores em suas hemácias para o vírus influenza, humano e eqüino d...

  12. Influenza em animais heterotérmicos

    OpenAIRE

    Dalva Assunção Portari Mancini; Rita Maria Zucatelli Mendonça; Aurora Marques Cianciarullo; Leonardo Setsuo Kobashi; Hermínio Gomes Trindade; Wilson Fernandes; José Ricardo Pinto

    2004-01-01

    O objetivo foi pesquisar Ortomyxovirus em animais heterotérmicos. Coletou-se sangue de serpentes dos gêneros Bothrops e Crotalus e de sapo e rãs dos gêneros Bufo e Rana, para a detecção dos receptores de hemácias e anticorpos específicos, ao vírus influenza, pelos testes de hemaglutinação e inibição da hemaglutinação, respectivamente. Pelo teste de hemaglutinação, verificou-se que serpentes e sapos em cativeiro apresentaram receptores em suas hemácias para o vírus influenza, humano e eqüino d...

  13. Fenomenologia e ontologia em Merleau-Ponty

    OpenAIRE

    Marcus Sacrini Ayres Ferraz

    2008-01-01

    Neste trabalho, buscamos expor e avaliar as diferentes concepções de ser defendidas por Merleau-Ponty no decorrer de sua obra. De início, explicitamos a concepção ontológica contida na Fenomenologia da Percepção, e julgamos que ela está comprometida com conseqüências idealistas. Em seguida, acompanhamos como Merleau-Ponty esboça, em seus textos finais, uma concepção não idealista do ser, que admite um excesso daquilo que há em relação àquilo que se fenomenaliza. In this work, we...

  14. Glutaminólise em astrocitomas

    OpenAIRE

    2014-01-01

    O metabolismo da glutamina (Gln) é alvo de atenções recentes para a compreensão da reprogramação metabólica para o suprimento energético das células tumorais em proliferação e para o desenvolvimento de novas estratégias terapêuticas em câncer. Tanto a absorção de glutamina quanto a taxa de glutaminólise, o catabolismo da Gln para gerar adenosina trifosfato (ATP) e lactato na mitocôndria estão aumentados em diferentes tumores. A Gln e glicose participam do processo da proliferação de células t...

  15. Preditores do Comportamento Antissocial em Adolescentes

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    Fernanda Lüdke Nardi

    Full Text Available RESUMO Este estudo investigou preditores do comportamento antissocial em 142 adolescentes em medida socioeducativa de internação (G1 e 691 estudantes de escolas públicas (G2, que responderam a um questionário. Foram observadas diferenças significativas entre os grupos quanto ao comportamento antissocial, violência intra e extrafamiliar, uso de drogas e eventos estressores, com médias mais altas em G1. Dentre as variáveis investigadas, grupo, uso de drogas e eventos estressores, juntamente com a covariável sexo, explicaram 66,5% da variável dependente. Um modelo de path analysis demonstrou que as variáveis sexo e ambiente estressor, computado pelos eventos estressores, qualidade do relacionamento familiar e violência intra e extrafamiliar predizem o uso de drogas e comportamentos antissociais.

  16. Tricolemoma em coelho Tricholemmoma in a rabbit

    Directory of Open Access Journals (Sweden)

    Krishna Duro de Oliveira

    1999-06-01

    Full Text Available Tricolemoma é um raro tumor benigno, composto por células epiteliais claras derivadas da bainha externa da raiz do folículo piloso. Esses tumores têm sido descritos no homem e raramente em cães. No presente relato, descreve-se a ocorrência de um tricolemoma, de 1cm de diâmetro em um coelho adulto, cujas características histológicas são muito semelhantes às descritas para esses tumores em cães.Tricholemmoma is a rare benign tumor composed of clear epithelial cells derived from the outer root sheath of the hair follicle. The tumor has been described in man and rarely in dogs. This report deals with the occurrence of a tricholemmoma , with a diemeter of 1cm, in an adult rabbit. The histologic features are similar to those described in such tumors in dogs.

  17. Ceratomicose em equinos Equine keratomycosis

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    Paula Diniz Galera

    2012-07-01

    Full Text Available O cavalo, dado o seu meio ambiente, está sujeito a afecções frequentes da córnea e da conjuntiva, tecidos oculares bastante expostos a bactérias e fungos, principalmente Aspergillus spp. e Fusarium spp. As ceratites ulcerativas bacterianas e fúngicas, bem como as ceratites fúngicas não ulcerativas, caracterizadas principalmente pelo abscesso estromal, são frequentes nessa espécie. Ocorrida a lesão inicial, perpetua-se um ciclo vicioso, com liberação de citocinas inflamatórias, que desencadeiam uma rápida e severa infiltração corneal por células polimorfonucleares. A córnea torna-se sujeita à destruição por enzimas proteolíticas liberadas pelos micro-organismos e por células inflamatórias, capazes de desencadear a dissolução estromal e a perfuração do bulbo ocular. O tratamento clínico para a resolução da doença corneal e o controle da uveíte reflexa deve ser agressivo e associado, muitas das vezes, à terapia cirúrgica. Este artigo discorre sobre a fisiopatologia e o tratamento da ceratomicose em equinos.Environmental and behavioral factors make horses susceptible to corneal and conjunctival lesions, since these structures are constantly exposed to bacteria and fungi specially Aspergillus spp. and Fusarium spp. Bacterial and fungal ulcerative keratitis, as well as non-ulcerative fungal keratitis such as stromal abscess, are frequent in horses. A "cascade" effect follows the initial lesion which triggers the release of inflammatory cytokines followed by an acute and severe infiltrate of polymorphonuclear cells in the cornea. The cornea becomes susceptible to the activity of proteolytic enzymes released by microorganisms and polymorphonuclear cells, resulting in stromal degradation and ocular perforation. The medical treatment targeting the corneal disease and the controlling of reflexive uveitis should be aggressive and surgical therapy should be associated in most of the cases. This paper reviews the

  18. Arthur Ramos: intelectual em perspectiva

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    Adir da Luz Almeida

    2016-03-01

    Full Text Available O trabalho constituise em resultado de pesquisa sobre o intelectual Arthur Ramos, suas reflexões teóricas e os efeitos no campo social e educativo. Arthur Ramos, intelectual complexo, multifacetado, refletiu sobre várias temáticas, pensando o Brasil como "nação" moderna, como outros intelectuais na passagem do século XIX para o século XX. Através redes de sociabilidade das quais participou e dos cargos públicos que ocupou, incluindo a chefia do Serviço de Ortofrenia e Higiene Mental do Instituto de Pesquisas Educacionais, na administração de Anísio Teixeira como Diretor de Instrução Pública, Rio de Janeiro, na década de 1930. Implanta o Serviço que tem como base a proximidade entre família, escola e comunidade, tendo como perspectiva alcançar as famílias e população pela escola. O foco é a discussão conceitual de "higiene" e "miscigenação", com atenção ao intelectual nesse debate, suas concepções, inflexões e contradições. São utilizadas como fontes algumas obras produzidas por Ramos, e arquivos sobre o SHOM, sob aguarda da Biblioteca Nacional.Palavras chave: intelectual, educação, historiografia, antropologia__________________Abstract: The work is the result of research on the intellectual Arthur Ramos, their theoretical reflections and the effects on social and educational field. Arthur Ramos, complex, multifaceted intellectual, reflected on several themes, thinking the Brazil as modern "nation", like other intellectuals in the passage from the XIX century to the XX century. Through social networks of which participated and the public office he held, including the leadership of the Ortofrenia Service and Mental Hygiene, of the Educational Research Institute, administration of Anísio Teixeira, as Director of Public Instruction, Rio de Janeiro, in the decade of 1930. Deploys the service that is based on the close the proximity between family, school and community, with the prospect to reach the families and

  19. The diet of the fox (<em>Vulpes vulpesem> in woodlands of Orobie Alps (Lombardy region, Northern Italy / Alimentazione della Volpe (<em>Vulpes vulpesem> in aree boscate delle Alpi Orobie

    Directory of Open Access Journals (Sweden)

    Marco Cantini

    1991-07-01

    Full Text Available Abstract The diet of the fox was investigated by analysis of 273 scats, collected along standard trails from April to November 1987 and 1988. Food habits of foxes were described for three altitudinal ranges. Mammals, mainly <em>Clethrionomys glareolusem> and <em>Microtus multiplexem>, were the staple food (percentage of frequency 42.8%, followed by fruits and other vegetables (26.7% and 37.3% respectively. Birds, Invertebrates (mainly Insects and garbage were little eaten. The game species (ungulates, hares, pheasants occurred with a low frequency (8.4% in the diet. The trophic niche breadth varied little through the altitudinal ranges and the seasons. The trophic niche overlap between the fox and the genus <em>Martes> (190 scats of <em>M. martesem> and <em>M. foinaem> were examined is relatively wide (O=0.868. Riassunto La dieta della Volpe (<em>Vulpes vulpesem> in aree boscate delle Alpi Orobie (Val Lesina è stata indagata nel periodo aprile-novembre 1987 e 1988 mediante l'analisi di 273 feci, raccolte lungo percorsi-campione ricadenti in tre piani vegetazionali. I Mammiferi, in particolare <em>Clethrionomys glareolusem> e <em>Microtus multiplexem>, sono la componente principale della dieta (frequenza percentuale 42,8%. Rilevante è anche il consumo di frutti (soprattutto in estate e autunno e di altri vegetali (26,7% e 37,3% rispettivamente, mentre poco frequente è quello di Uccelli, Invertebrati e rifiuti. Complessivamente ridotta è l'azione predatoria della Volpe nei confronti delle specie di interesse venatorio (Ungulati, lepri, Galliformi. L'ampiezza della nicchia trofica mostra modeste variazioni stagionali e altitudinali. I1 grado di sovrapposizione tra la nicchia trofica della Volpe e quella del genere <em>Martes>, quest'ultima ricavata dall'analisi di 190 feci di Martora (<em>M. martesem> e Faina (<em>M. foinaem>, è elevato (O=0,868. Tuttavia, poiché in condizioni di

  20. Electroweak production of single {\\em W} and {\\em Z} bosons in ATLAS and CMS

    CERN Document Server

    Leite, Marco Aurelio Lisboa; The ATLAS collaboration

    2016-01-01

    Results on the production of single {\\em Z} and {\\em W} bosons with two jets at high invariant mass at a centre-of-mass energy of 8 TeV are presented using data corresponding to 20.3 fb$^\\mathrm{-1}$. Integrated and differential cross sections are measured in many different phase space regions with varying degree of sensitivity to the electroweak production in vector boson fusion by both ATLAS and CMS. The results have also been used to derive limits on anomalous triple gauge couplings in the single {\\em Z} production.

  1. A Novel Cyclodextrin Glycosyltransferase from Alkaliphilic <em>Amphibacillus> sp. NPST-10: Purification and Properties

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    Garabed Antranikian

    2012-08-01

    Full Text Available Screening for cyclodextrin glycosyltransferase (CGTase-producing alkaliphilic bacteria from samples collected from hyper saline soda lakes (Wadi Natrun Valley, Egypt, resulted in isolation of potent CGTase producing alkaliphilic bacterium, termed NPST-10. 16S rDNA sequence analysis identified the isolate as <em>Amphibacillus> em>sp. CGTase was purified to homogeneity up to 22.1 fold by starch adsorption and anion exchange chromatography with a yield of 44.7%. The purified enzyme was a monomeric protein with an estimated molecular weight of 92 kDa using SDS-PAGE. Catalytic activities of the enzyme were found to be 88.8 U mg−1 protein, 20.0 U mg−1 protein and 11.0 U mg−1 protein for cyclization, coupling and hydrolytic activities, respectively. The enzyme was stable over a wide pH range from pH 5.0 to 11.0, with a maximal activity at pH 8.0. CGTase exhibited activity over a wide temperature range from 45 °C to 70 °C, with maximal activity at 50 °C and was stable at 30 °C to 55 °C for at least 1 h. Thermal stability of the purified enzyme could be significantly improved in the presence of CaCl2. <em>K>m and <em>V>max values were estimated using soluble starch as a substrate to be 1.7 ± 0.15 mg/mL and 100 ± 2.0 μmol/min, respectively. CGTase was significantly inhibited in the presence of Co2+, Zn2+, Cu2+, Hg2+, Ba2+, Cd2+, and 2-mercaptoethanol. To the best of our knowledge, this is the first report of CGTase production by <em>Amphibacillus> sp. The achieved high conversion of insoluble raw corn starch into cyclodextrins (67.2% with production of mainly β-CD (86.4%, makes <em>Amphibacillus> sp. NPST-10 desirable for the cyclodextrin production industry.

  2. Trabalho fonoaudiologico em oficina de cozinha em um caso de Prader-Willi

    OpenAIRE

    Zambotti, Nathalia; SOUZA, Luiz Augusto de Paula

    2013-01-01

    TEMA: o objetivo deste estudo é descrever e analisar os efeitos do trabalho fonoaudiológico em Oficina de Cozinha, em processo terapêutico de um paciente portador da síndrome de Prader-Willi. PROCEDIMENTOS: a pesquisa é um estudo de caso de uma criança de 5 anos portadora da Síndrome de Prader-Willi, que apresentava atraso de linguagem e transtornos alimentares. A criança participou durante sete meses do processo terapêutico em Oficina de Cozinha, associado à terapia fonoaudiológica individua...

  3. Fauna de morcegos em remanescentes urbanos de Cerrado em Campo Grande, Mato Grosso do Sul

    OpenAIRE

    Ferreira, Cláudia Márcia Marily; Fischer,Erich; Pulchério-Leite,Atenise

    2010-01-01

    Campo Grande é a maior cidade do Estado de Mato Grosso do Sul, localizada no domínio do Cerrado, um hotspot de biodiversidade. A fauna de morcegos urbanos tem sido pouco estudada no Brasil, principalmente em cidades na região do Cerrado. O principal objetivo aqui é descrever a composição, a riqueza e a diversidade da fauna de morcegos em remanescentes de Cerrado na região urbana de Campo Grande. Amostragens de morcegos foram feitas entre março e agosto de 2009 em oito parques urbanos com auxí...

  4. Variabilità microsatellitare in popolazioni italiane di martora, <em>Martes martesem>

    Directory of Open Access Journals (Sweden)

    Licia Colli

    2003-10-01

    Full Text Available La martora, <em>Martes martesem>, è un mustelide storicamente presente su gran parte del territorio italiano, soprattutto dove siano presenti foreste mature altamente strutturate e ricche di risorse. Nel corso dei decenni passati, cause quali la deforestazione con conseguente frammentazione dell'habitat, la caccia e la persecuzione da parte dell'uomo hanno portato ad un sensibile declino sia nel numero d'individui sia di popolazioni in tutta l'Europa. Frammentazione degli areali e diminuzione del numero di soggetti costituiscono le cause principali di un limitato flusso genico con conseguente formazione di popolazioni isolate di martora e perdita di variabilità genetica (Kyle <em>et al.em>, 2003. Per queste ragioni la martora risulta attualmente tutelata secondo quanto previsto dalla Convenzione di Berna (appendice III e dalla Direttiva europea 92/43/CEE "Habitats & Species". Di fronte a prospettive di tipo conservazionistico, diventa necessario disporre di metodologie per la valutazione della variabilità residua nella specie a livello d'individui e di popolazioni. Secondo numerosi Autori, i microsatelliti costituiscono marcatori molto efficaci nella descrizione della struttura genetica e della storia demografica di specie (Beaumont & Bruford, 1999; Linares, 1999. Il presente lavoro propone i risultati ottenuti attraverso il confronto di due campioni costituiti da individui di <em>Martes martesem> provenienti dalla Sardegna (25 esemplari e dal territorio italiano (6 esemplari. L'analisi è stata condotta a livello di 7 loci microsatellitari dinucleotidici polimorfici. Il valore di FST calcolato dal confronto dei due gruppi è risultato pari a 0,102 e ricade nel <em>range> di variazione identificato di recente in popolazioni nord-europee di martora (Kyle <em>et al.em>, 2003. L'analisi della varianza molecolare (AMOVA, condotta a due livelli gerarchici, ha permesso in particolare di ripartire la varianza del campione

  5. EMS applications integration in a SCADA; Integracion de aplicaciones EMS en un SCADA

    Energy Technology Data Exchange (ETDEWEB)

    Roses, Rodolfo; Colome, D.G.; Orduna, E.; Vega, C. de la; Camisay, G. [Universidad Nacional de San Juan (Argentina). Inst. de Energia Electrica]. E-mail: roses@iee.unsj.edu.ar

    2001-07-01

    This paper presents the methodology to integrate EMS (Energy Management System) functions in a SCADA system (System Control and Data Acquisition). The implementation methodology of the EMS applications has included the design and database implementation, EMS-SCADA communication, results presentation, logics definition of execution and processing ways. The applications portability characteristics allow integration with different SCADA system with some adaptations on the data communication interface. Thus, a open system has been obtained and implemented successfully in the control center of an Argentine 132 kV network.

  6. A singularidade do totalitarismo em Hannah Arendt

    Directory of Open Access Journals (Sweden)

    José João Neves Barbosa Vicente

    2011-07-01

    Full Text Available

    A partir da análise da obra <em style="mso-bidi-font-style: normal;">Origens do totalitarismoem> (1990, este artigo apresenta de um modo introdutório, alguns motivos que levaram Hannah Arendt a denominar o totalitarismo de acontecimento singular na história da humanidade.

  7. Risk Communication Within the EM Program

    Energy Technology Data Exchange (ETDEWEB)

    Edelson, M.

    2003-02-26

    The U.S. Department of Energy Environmental Management program (EM) conducts the most extensive environmental remediation effort in the world. The annual EM budgets have exceeded $6,000,000,000 for approximately ten years and EM has assumed responsibility for the cleanup of the largest DOE reservations (i.e., at Hanford, Washington, Aiken, South Carolina, and Idaho Falls, Idaho) as well as the facilities at Rocky Flats, Colorado and in Ohio. Each of these sites has areas of extensive radioactive and chemical contamination, numerous surplus facilities that require decontamination and removal, while some have special nuclear material that requires secure storage. The EM program has been criticized for being ineffective (1) and has been repeatedly reorganized to address perceived shortcomings. The most recent reorganization was announced in 2001 to become effective at the beginning of the 2003 Federal Fiscal Year (i.e., October 2002). It was preceded by a ''top to bottom'' review (TTBR) of the program (2) that identified several deficiencies that were to be corrected as a result of the reorganization. One prominent outcome of the TTBR was the identification of ''risk reduction'' as an organizing principle to prioritize the activities of the new EM program. The new program also sought to accelerate progress by identifying a set of critical activities at each site that could be accelerated and result in more rapid site closure, with attendant risk, cost, and schedule benefits. This paper investigates how the new emphasis on risk reduction in the EM program has been communicated to EM stakeholders and regulators. It focuses on the Rocky Flats Environmental Technology Site (RFETS) as a case study and finds that there is little evidence for a new emphasis on risk reduction in EM communications with RFETS stakeholders. Discussions between DOE and RFETS stakeholders often refer to ''risk,'' but the word serves as a

  8. Compreendendo o ambiente em Psicologia Ambiental

    OpenAIRE

    Lenelis Kruse

    2005-01-01

    O presente artigo consiste nas respostas às seguintes perguntas, propostas e respondidas pela autora: De que modo você, como uma psicóloga ambiental ou pesquisadora ambiente-comportamento: define o ambiente; leva em conta o ambiente em sua pesquisa; que tipo de teorias necessitamos para responder pelas relações pessoas-ambiente mais efetivamente; a interação entre as pessoas e o ambiente foi suficiente e adequadamente explicada na Psicologia Ambiental; de que modo esta interação poderia ser e...

  9. Úlcera gastroduodenal em potros

    OpenAIRE

    Dearo,Antonio Cezar de Oliveira; LOPES, Marco Aurélio Ferreira

    1995-01-01

    Dentre as inúmeras patologias que acometem os eqüinos jovens, as úlceras gástricas situam-se como uma das mais importantes. MURRAY et al. (1987) trabalhando com potros clinicamente normais, constatou uma prevalência de úlceras da ordem de 51%. O mesmo autor realizando gastroscopia em 45 equinos com idade entre 1 e 24 anos, observou a presença de úlceras em 93% dos animais (MURRAY, 1988). De etiologia não completamente definida, acredita-se que inúmeros fatores estejam envolvidos na gênese das...

  10. O potencial evocado cognitivo em adultos normais

    Directory of Open Access Journals (Sweden)

    Franco Glaucio M.

    2001-01-01

    Full Text Available O objetivo deste estudo foi avaliar os resultados do potencial cognitivo auditivo em um grupo de adultos normais. Os testes foram realizados registrando-se a resposta evocada em Cz e Fz. Os dados obtidos foram analisados estatisticamente. São descritas neste trabalho as latências médias de N1, P2, P2AP, N2 e P3, a amplitude de P3, bem como o desvio padrão destas variáveis. Comentam-se algumas dificuldades encontradas na interpretação do teste destacando as limitações de seu uso clínico.

  11. Configuring systems from components: the EMS approach

    Energy Technology Data Exchange (ETDEWEB)

    Nogiec, J.M. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States)]. E-mail: nogiec@fnal.gov; Desavouret, E. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Kotelnikov, S. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Trombly-Freytag, K. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Walbridge, D. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States)

    2004-11-21

    EMS is an exercise in component technology. It offers rapid development of specialized data acquisition, visualization and analysis systems via assembly from vertical and horizontal components. The EMS architecture allows for agile development of systems and promotes reuse of software. The framework supports a visual builder that shows connections between components and lists component properties. The system offers both off-line setup of properties and run-time modifications. Multi-bus architecture allows for independent routing of data, controls, debugs, and exceptions. The architecture, configuration process, and control of applications through scripting are presented.

  12. Portalegre em múltiplas vistas

    OpenAIRE

    Martins, Moisés de Lemos; Correia, Maria Da Luz

    2011-01-01

    Obra completa "Martins, Moisés de Lemos e Oliveira, Madalena, coords. - Portugal Ilustrado em postais: Bragança, Viana do Castelo, Braga, Viseu, Portalegre. Disponível em http://hdl.handle.net/1822/36492" A Praça da República apagada, um tanto desabrigada, com tábuas velhas no chão ao abandono, ou então, desperta e vivaz, percorrida pelas cores da modernidade e dos automóveis; os olhares da rua 5 de Outubro, parados diante da objectiva fotográfica; os azulejos do Palácio Achioli; o edifíci...

  13. Microbiota conjuntival em pacientes com alergia ocular

    OpenAIRE

    Alexandre Mattoso Libório; Maria Cristina Nishiwaki-Dantas; Lycia Mara Jenne Mimica; Paulo Elias Correa Dantas; Ana Luísa Höfling de Lima

    2005-01-01

    OBJETIVO: Avaliar a presença de microbiota aeróbia da conjuntiva de portadores de alergia ocular e comparar a um grupo controle. MÉTODOS: Foram examinados 133 pacientes no período de abril a junho de 2001 divididos em 2 grupos. O grupo A foi composto de 63 portadores de conjuntivite alérgica (sem uso de medicação) e o grupo B de 70 pacientes do ambulatório geral (controle). Foram coletadas amostras do fundo de saco conjuntival do olho direito de todos os pacientes e o material foi semeado em ...

  14. Acupuntura em adolescentes com fibromialgia juvenil

    OpenAIRE

    Dias,Marialda Höfling P.; Amaral,Elisabete; PAI, Hong Jin; Daniela Terumi Y. Tsai; LOTITO, Ana Paola N; Leone,Claudio; Silva, Clovis Artur

    2012-01-01

    OBJETIVO: Descrever a utilização da acupuntura em adolescentes com fibromialgia juvenil. MÉTODOS: Estudo retrospectivo realizado em pacientes com fibromialgia juvenil (critérios do Colégio Americano de Reumatologia) submetidos a, pelo menos, 11 sessões semanais de acupuntura. As avaliações antes e após acupuntura incluíram dados demográficos, características da dor musculoesquelética, número de pontos dolorosos (NPD), escala visual analógica (EVA) de dor, algiometria e índice miálgico (IM). D...

  15. The Complete Mitochondrial Genome of the Pink Stem Borer, <em>Sesamia inferensem>, in Comparison with Four Other Noctuid Moths

    Directory of Open Access Journals (Sweden)

    Yu-Zhou Du

    2012-08-01

    Full Text Available The complete 15,413-bp mitochondrial genome (mitogenome of <em>Sesamia inferensem> (Walker (Lepidoptera: Noctuidae was sequenced and compared with those of four other noctuid moths. All of the mitogenomes analyzed displayed similar characteristics with respect to gene content, genome organization, nucleotide comparison, and codon usages. Twelve-one protein-coding genes (PCGs utilized the standard ATN, but the <em>cox1 em>gene used CGA as the initiation codon; <em>cox1em>, <em>cox2em>, and <em>nad4em> genes had the truncated termination codon T in the <em>S. inferens em>mitogenome. All of the tRNA genes had typical cloverleaf secondary structures except for <em>trnS1(AGNem>, in which the dihydrouridine (DHU arm did not form a stable stem-loop structure. Both the secondary structures of <em>rrnL> and <em>rrnS> genes inferred from the <em>S. inferens em>mitogenome closely resembled those of other noctuid moths. In the A+T-rich region, the conserved motif “ATAGA” followed by a long T-stretch was observed in all noctuid moths, but other specific tandem-repeat elements were more variable. Additionally, the <em>S. inferens em>mitogenome contained a potential stem-loop structure, a duplicated 17-bp repeat element, a decuplicated segment, and a microsatellite “(AT7”, without a poly-A element upstream of the<em> trnM em>in the A+T-rich region. Finally, the phylogenetic relationships were reconstructed based on amino acid sequences of mitochondrial 13 PCGs, which support the traditional morphologically based view of relationships within the Noctuidae.

  16. Fire and EMS Districts, EMS Districts, Published in 2007, 1:24000 (1in=2000ft) scale, Iron County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Fire and EMS Districts dataset, published at 1:24000 (1in=2000ft) scale, was produced all or in part from Other information as of 2007. It is described as 'EMS...

  17. Development of Nine Markers and Characterization of the Microsatellite Loci in the Endangered <em>Gymnogobius isazaem> (Gobiidae

    Directory of Open Access Journals (Sweden)

    Hiroshi Kudoh

    2012-05-01

    Full Text Available <em>Gymnogobius isazaem> is a freshwater goby endemic to Lake Biwa, Japan. They experienced a drastic demographic bottleneck in the 1950s and 1980s and slightly recovered thereafter, but the population size is still very small. To reveal dynamics of genetic diversity of <em>G. isazaem>, we developed nine microsatellite markers based on the sequence data of a related goby <em>Chaenogobius annularisem>. Nine SSR (Simple Sequence Repeats markers were successfully amplified for raw and formalin-fixed fish samples. The number of alleles and expected heterozygosities ranged from one to 10 and from 0.06 to 0.84, respectively, for the current samples, while one to 12 and 0.09 to 0.83 for historical samples. The markers described here will be useful for investigating the genetic diversity and gene flow and for conservation of <em>G. isazaem>.

  18. The role of common toads in the winter diet of recolonising Eurasian otters (<em>Lutra lutraem>

    Directory of Open Access Journals (Sweden)

    Pablo García-Díaz

    2011-02-01

    Full Text Available Importanza del rospo comune nella dieta invernale di una popolazione di lontra (<em>Lutra lutraem> in espansione.
    Tramite analisi dei resti fecali, abbiamo evidenziato il ruolo fondamentale degli anfibi nella dieta invernale della lontra <em>Lutra lutraem> in stagni artificiali della Spagna nord-occidentale. I numerosi “laghi di cava” presenti nell’area umida di Ribeiras do Louro e Gandaras de Budiño sono stati monitorati nel 2007-2009. Il rospo comune (<em>Bufo bufoem> era la principale preda della lontra, costituendo l’88% della biomassa consumata, mentre il gambero americano <em>Procambarus clarkiiem> e i pesci erano prede secondarie. I nostri risultati contrastano con la ben nota preferenza della lontra per le rane rispetto al rospo. Il mantenimento della popolazione di lontra nel bacino del fiume Louro dipende strettamente dalla corretta gestione degli stagni artificiali.

  19. Syntheses of Enantiopure Aliphatic Secondary Alcohols and Acetates by Bioresolution with Lipase B from <em>Candida antarcticaem>

    Directory of Open Access Journals (Sweden)

    Richele P. Severino

    2012-07-01

    Full Text Available The lipase B from <em>Candida antarcticaem> (Novozym 435®, CALB efficiently catalyzed the kinetic resolution of some aliphatic secondary alcohols: (±-4-methylpentan-2-ol (1, (±-5-methylhexan-2-ol (3, (±-octan-2-ol (4, (±-heptan-3-ol (5 and (±-oct-1-en-3-ol (6. The lipase showed excellent enantioselectivities in the transesterifications of racemic aliphatic secondary alcohols producing the enantiopure alcohols (>99% <em>ee> and acetates (>99% <em>ee> with good yields. Kinetic resolution of <em>rac>-alcohols was successfully achieved with CALB lipase using simple conditions, vinyl acetate as acylating agent, and hexane as non-polar solvent.

  20. Design of Higher-<em>k> and More Stable Rare Earth Oxides as Gate Dielectrics for Advanced CMOS Devices

    Directory of Open Access Journals (Sweden)

    Yi Zhao

    2012-08-01

    Full Text Available High permittivity (<em>k> gate dielectric films are widely studied to substitute SiO2 as gate oxides to suppress the unacceptable gate leakage current when the traditional SiO2 gate oxide becomes ultrathin. For high-<em>k> gate oxides, several material properties are dominantly important. The first one, undoubtedly, is permittivity. It has been well studied by many groups in terms of how to obtain a higher permittivity for popular high-<em>k> oxides, like HfO2 and La2O3. The second one is crystallization behavior. Although it’s still under the debate whether an amorphous film is definitely better than ploy-crystallized oxide film as a gate oxide upon considering the crystal boundaries induced leakage current, the crystallization behavior should be well understood for a high-<em>k> gate oxide because it could also, to some degree, determine the permittivity of the high-<em>k> oxide. Finally, some high-<em>k> gate oxides, especially rare earth oxides (like La2O3, are not stable in air and very hygroscopic, forming hydroxide. This topic has been well investigated in over the years and significant progresses have been achieved. In this paper, I will intensively review the most recent progresses of the experimental and theoretical studies for preparing higher-<em>k> and more stable, in terms of hygroscopic tolerance and crystallization behavior, Hf- and La-based ternary high-<em>k> gate oxides.

  1. Dynamic classification of global sedimentary basins: Based on proto-type basin and its lateral superimposing and transforming process%全球沉积盆地动态分类方法:从原型盆地及其叠加发展过程讨论

    Institute of Scientific and Technical Information of China (English)

    温志新; 童晓光; 张光亚; 王兆明; 宋成鹏

    2012-01-01

    Sedimentary basin is a basic geological unit of oil generation and accumulation and its formation and development is mainly controlled by plate tectonic evolution, shown as follows: (1) different stages of plate evolution from divergence to convergence and plate at different positions resulted in different proto-type basins and formed specific structure-depositional systems, which determined its basic oil and gas bearing conditions, such as source rocks, reservoirs, seals, etc. ; (2) the lateral superimposed proto-type basins not only have its own characteristics of petroleum geology, but also can change the former proto-type basins' oil and gas accumulation condition and distribution rules. In this paper, taking plate tectonic evolution history as a time clue, the author divided basins of modern world that were in a Wilson cycle into 12 types with a dynamic method, and through the systematic anatomy of early proto-type of today' s basins and its lateral superimposing and transforming process. Based on it, the basic properties and oil and gas bearing conditions of various types of basins are summarized, which may lay a foundation for scientific forecast of hydrocarbon potential of various types of basins.%沉积盆地是油气生成和聚集的基本地质单元,其形成和发展为板块构造演化所控制,主要表现在两个方面,一是板块从分离到汇聚的不同阶段、板块的不同位置,产生不同的原型盆地,形成了特定的构造-沉积体系,决定了其生、储、盖等基本含油气条件;二是后期叠加的原型盆地不但本身具有新的油气地质特征,还能够改变早期原型盆地的成藏条件及油气分布规律。以板块构造演化历史为时间线索,通过对现今盆地早期原型及其后期叠加改造过程的系统解剖,用动态方法将全球处于一个威尔逊旋回的现今盆地划分为12种类型。在此基础上,总结了各类盆地的基本属性及含油气条件,为科

  2. Matérias estranhas em canela em pó e páprica em pó, comercializadas no estado de São Paulo

    Directory of Open Access Journals (Sweden)

    CORREIA Marlene

    2000-01-01

    Full Text Available Com objetivos de padronizar metodologias para matérias estranhas em canela em pó e páprica em pó e de avaliar as condições higiênicas desses condimentos, foram adquiridas, no período de agosto a novembro de 1998, 78 amostras de canela em pó e 56 de páprica em pó, em estabelecimentos comerciais de seis cidades do Estado de São Paulo. Foram utilizados métodos da Association of Official Analytical Chemists International (AOAC - 1995, 16.14.12/968.38b para canela em pó e 16.14.22/977.25B para páprica em pó. Os métodos mostraram-se adequados, sem resíduos interferentes no papel de filtro que dificultasse o diagnóstico da análise e viáveis de serem utilizados nos laboratórios de Microscopia de Alimentos. Os resultados obtidos indicaram 100% das amostras contendo fragmentos de insetos; pêlos de roedor foram isolados em 73,1% de amostras de canela em pó e 34,0% de páprica em pó, enquanto ácaros mortos apareceram, respectivamente, em 37,2% e 12,5% de amostras. É necessário revisão da legislação de alimentos em vigor, com o estabelecimento de níveis de tolerância para fragmentos de insetos.

  3. Osservazioni in cattività sul ciclo stagionale del peso corporeo e sull'efficienza digestiva di <em>Pipistrellus kuhliiem> e <em>Hypsugo saviiem> (Chiroptera: Verspertilionidae

    Directory of Open Access Journals (Sweden)

    Gianna Dondini

    2004-06-01

    Full Text Available Abstract Captivity observation on body weight cycle and digestive efficiency in <em>Pipistrellus kuhliiem> and <em>Hypsugo saviiem> (Chiroptera: Vespertilionidae Many bat species of cold-temperate climate are subject to seasonal variation of temperature and food availability. Fat reserve during summer-autumn is therefore a physiological adaptation to spend the winter months by hibernating or to sustain migration. During a research on bats in urban areas, two juveniles of Kuhl's bat (<em>Pipistrellus kuhliiem>, 2 females and two juveniles of Savi's bat (<em>Hypsugo saviiem>, 1 male and 1 female were collected in 1997 in the urban area of Florence (central Italy. Bats were kept in a cage of 50x40x30 cm with a temperature between 17° and 22° C. Every day they were weighted with an electronic balance before eating mealworms (<em>Tenebrio molitorem>. Digestive efficiency, calculated on dry material, was about 90% for both species. In about six months <em>P. kuhliiem> and <em>H. saviiem> increased on the average of 450% and 280% in weight respectively. Deposition of fat reserve seemed to be faster in <em>P. kuhliiem> than in <em>H. saviiem>. Both species showed a circannual cycle in the variation of weight. Riassunto Molte specie di pipistrelli dei climi temperato-freddi sono soggette a marcate variazioni stagionali di temperatura e disponibilità di cibo. L'accumulo di grasso in tarda estate-autunno è quindi un adattamento fisiologico per trascorrere in ibernazione i mesi invernali o per intraprendere la migrazione. Nell'ambito di una ricerca pluriennale sui pipistrelli in ambienti urbani, 4 esemplari giovani, di cui 2 di Pipistrello albolimbato (<em>Pipistrellus kuhliiem>, 2 femmine e due di Pipistrello di Savi (<em>Hypsugo saviiem>, 1 maschio e 1 femmina, sono stati raccolti nella pianura di Firenze durante l'estate del 1997 e mantenuti in un contenitore di 50x40x30 cm ad

  4. <em>Botulinum Neurotoxinem> A Injections Influence Stretching of the Gastrocnemius Muscle-Tendon Unit in an Animal Model

    Directory of Open Access Journals (Sweden)

    Christopher J. Tuohy

    2012-08-01

    Full Text Available <em>Botulinum Neurotoxinem> A (BoNT-A injections have been used for the treatment of muscle contractures and spasticity. This study assessed the influence of (BoNT-A injections on passive biomechanical properties of the muscle-tendon unit. Mouse gastrocnemius muscle (GC was injected with BoNT-A (<em>n> = 18 or normal saline (<em>n> = 18 and passive, non-destructive, <em>in vivoem> load relaxation experimentation was performed to examine how the muscle-tendon unit behaves after chemical denervation with BoNT-A. Injection of BoNT-A impaired passive muscle recovery (15% <em>vs.> 35% recovery to pre-stretching baseline, <em>p> < 0.05 and decreased GC stiffness (0.531 ± 0.061 N/mm <em>vs.> 0.780 ± 0.037 N/mm, <em>p> < 0.05 compared to saline controls. The successful use of BoNT-A injections as an adjunct to physical therapy may be in part attributed to the disruption of the stretch reflex; thereby modulating <em>in vivoem> passive muscle properties. However, it is also possible that BoNT-A injection may alter the structure of skeletal muscle; thus modulating the <em>in vivoem> passive biomechanical properties of the muscle-tendon unit.

  5. Winter survival of <em>Apodemus flavicollisem> in Crabapple island (NE Poland

    Directory of Open Access Journals (Sweden)

    Gabriela Bujalska

    2006-09-01

    Full Text Available Riassunto Sopravvivenza invernale di <em>Apodemus flavicollisem> nell’isola di Crabapple (Polonia nord orientale. Nel corso di nove anni consecutivi (1994-2003, la sopravvivenza invernale di <em>Apodemus flavicollisem> è stata indagata nell’isola di Crabapple (4 ha tramite cinque serie annuali di trappolaggi condotte tra Aprile ed Ottobre. Le condizioni climatiche invernali sono state espresse tramite 22 variabili relative a piovosità, temperatura e precipitazioni nevose. La percentuale di animali sopravvissuti è variata dal 5,3% al 51,1%, senza mostrare alcuna relazione con le variabili climatiche e con la consistenza della popolazione a inizio inverno. Tra le variabili individuali considerate (età, stato riproduttivo, massa corporea, la maturità sessuale sembra essere l’unica a favorire la sopravvivenza invernale, in contrasto con le informazioni disponibili in letteratura.

  6. First records of the northern raccoon <em>Procyon lotorem> in Italy

    Directory of Open Access Journals (Sweden)

    Luca Canova

    2009-02-01

    Full Text Available Riassunto Prime segnalazioni del procione <em>Procyon lotorem> in Italia In Lombardia fra il 2004 e il 2008 sono stati segnalati 10 individui di procione <em>Procyon lotorem>. La distribuzione delle osservazioni è coerente con l'areale attualmente occupato dalla specie in Europa. Il fatto che le osservazioni siano avvenute lungo il corso dell'Adda e dei canali da esso alimentati permettedi ipotizzare che la specie abbia colonizzato il paese seguendo una rotta di dispersione che connette l'area del lago di Como alla Svizzera e al corso del fiume Adda. L'osservazione di giovani suggerisce l'esistenza di una popolazione riproduttiva in Italia.

  7. Phylattrin, a New Cytotoxic Xanthone from <em>Calophyllum soulattriem>

    Directory of Open Access Journals (Sweden)

    Siau Hui Mah

    2012-07-01

    Full Text Available Our continuing studies on secondary metabolites from the stem bark of <em>Calophyllum soulattriem> has led to the isolation of another new diprenylated xanthone, phylattrin (1, in addition to five other xanthones and two common sterols. The xanthones are soulattrin (2, caloxanthone C (3, macluraxanthone (4, brasixanthone B (5 and trapezifolixanthone (6 while the sterols are stigmasterol (7 and <em>β>-sitosterol (8. The structures of these compounds were determined on the basis of spectroscopic analyses such as 1D and 2D-NMR, HRESIMS, IR and UV. Compounds 17 exhibited moderate cytotoxic activities against SNU-1, HeLa, Hep G2, NCI-H23, K562, Raji, LS174T, IMR-32 and SK-MEL-28 cells.

  8. Marcha em pontas idiopática em idade pediátrica

    OpenAIRE

    Sara Domingues; Cláudia Melo; Catarina Magalhães; Sónia Figueiroa; Inês Carrilho; Teresa Temudo

    2016-01-01

    A marcha em pontas tem uma incidência de 7-24% na população pediátrica em geral e é uma causa relativamente frequente de referenciação à consulta de neurologia pediátrica. A marcha em pontas idiopática ocorre em crianças saudáveis, sem espasticidade e com reflexos osteotendinosos normais; é evidente desde o início da marcha autónoma, sempre bilateral e não progressiva. A sua etiologia é desconhecida, pelo que se trata de um diagnóstico de exclusão. Assim, na avaliação destas crianças é essenc...

  9. Paisagens etnicas em Curitiba: um olhar histórico-espacial em busca de entopia /

    OpenAIRE

    Kanashiro, Milena

    2006-01-01

    Orientadora: Yara Vicentini Inclui apendice Tese (doutorado) - Universidade Federal do Paraná, Programa de Pós-Graduaçăo em Meio Ambiente e Desenvolvimento. Defesa: Curitiba, 2006 Inclui bibliografia

  10. Marcha em pontas idiopática em idade pediátrica

    OpenAIRE

    Sara Domingues; Cláudia Melo; Catarina Magalhães; Sónia Figueiroa; Inês Carrilho; Teresa Temudo

    2016-01-01

    A marcha em pontas tem uma incidência de 7-24% na população pediátrica em geral e é uma causa relativamente frequente de referenciação à consulta de neurologia pediátrica. A marcha em pontas idiopática ocorre em crianças saudáveis, sem espasticidade e com reflexos osteotendinosos normais; é evidente desde o início da marcha autónoma, sempre bilateral e não progressiva. A sua etiologia é desconhecida, pelo que se trata de um diagnóstico de exclusão. Assim, na avaliação destas crianças é essenc...

  11. Amor e liberdade em Heidegger

    Directory of Open Access Journals (Sweden)

    Acylene Maria Cabral Ferreira

    2011-06-01

    Full Text Available Nosso objetivo é mostrar, a partir das obras Ser e Tempo e Seminários de Zollikon, a constituição ontológica do amor como a afinação (Stimmung fundamental para a convivência da presença (Dasein. Nossa hipótese sustenta-se no pressuposto que a copertença do amor (abertura fundamental para o outro e da liberdade (deixar-ser o outro consiste em uma modificação do existencial da disposição e expressa a unidade e a circularidade ontológica do ser-no-mundo. Pretendemos mostrar ainda que a solicitude (a abertura do ser-com é a condição de possibilidade para a constituição ontológico-existencial da afinação do amor. Centrados no texto Sobre a essência da verdade, nosso intuito é sublinhar que a liberdade é também uma modificação do existencial da disposição, ou seja, uma afinação, e enquanto tal é o fundamento ontológico para o desvelamento do modo próprio (eigentliche de ser da presença. Nesta perspectiva, podemos afirmar que a afinação da liberdade precede e penetra a afinação do amor. Isto significa que a afinação do amor se funda na afinação da liberdade e que esta ressoa naquela, o que nos permite dizer que elas são co-originárias.The objective of the present paper is to show, using Being and time and Zollikon Seminars, the existential-ontological constitution of love as a mood (Stimmung fundamental to the coexistence of Dasein. The hypothesis advanced here is that the co-pertinence of love (the fundamental disclosedness to the other and of freedom (the letting-be of the other consists in a modification of the existential of state-of-mind and expresses the unity and ontological circularity of Being-in-the-world. We intend also to show that solicitude (the disclosedness towards Being-with is the condition of possibility for the existential-ontological constitution of the mood of love. Centered on the text On the Essence of Truth, our purpose is to emphasize that freedom is also a modification of the

  12. Relato de caso: eritema multiforme em criança em idade escolar

    Directory of Open Access Journals (Sweden)

    Camila Voos Camila Voos Soares

    2015-12-01

    Full Text Available O eritema multiforme (EM se caracteriza por uma reação imunológica que afeta pele e mucosa mais comumente observada após infecções virais, principalmente por herpes vírus (HSV. Relato de caso: paciente feminina, 8 anos, inicia com quadro de dor e edema em mãos. Evoluiu com vesículas e bolhas em tronco, dorso e face, mas em maior concentração em mãos e pés com acometimento de palmas e plantas. As bolhas eram tensas com base eritematosa e algumas com crosta. Discussão: as lesões cutâneas comumente aparecem em regiões de extremidades como mãos e pés: são planas, redondas e vermelho escuras, tendo o formato de anéis eritematosos e circulares concêntricos em forma de alvo, também conhecido como “olho de boi”. O diagnóstico do EM é clínico e pode ser definido com a coexistência de lesões em alvo geralmente associado à infecção prévia ou atual por HSV, não necessitando de biópsia, quando a apresentação é típica. A biópsia pode auxiliar nos casos atípicos, como diagnósticos de exclusão. Considerações finais: o presente relato de caso demonstrou uma doença rara (estimado em 1,2-6 casos por milhão/ano, principalmente na faixa etária escolar. Além disso, teve uma apresentação atípica, tendo em vista a exuberância das lesões bolhosas.

  13. Palo Monte, um rito Congo em Cuba

    Directory of Open Access Journals (Sweden)

    José da Silva Ribeiro

    2007-01-01

    Full Text Available Juntaram-se em Cuba a partir do século XVI africanos provenientes de toda a costa ocidental africana pertencentes a muitos grupos étnicos. Estes em contacto com as culturas em presença (autóctone, espanhola, portuguesa, africanas desenvolveram diversos sistemas de crença, rituais e práticas mágico-religiosas. No Século XIX o dia de Reis construía o momento mais alto da afirmação da cultura africana em Cuba. Estas manifestações eram acompanhadas da coroação de reis e rainhas Congo, figuras principais da festa e da vida social africana.Africans coming from all West Africa coasts from a large variety of ethnic groups gathered in Cuba since XVIth century. These, in contact with other cultures (native, Spanish, Portuguese, Africans developed some belief systems, rituals and magical-religious practices. On XIXth century the King’s day was the highest moment of affirmation of African culture in Cuba. These experiences were accompanied of king and queen’s crowning, principal figures of African festival and social life.

  14. Biodiversidade do solo em ecossistemas brasileiros

    NARCIS (Netherlands)

    Moreira, F.M.S.; Siqueira, J.O.; Brussaard, L.

    2008-01-01

    Biodiversidade do Solo em Ecossistemas Brasileiros R,00 O solo é considerado o ecossistema mais complexo e dinâmico do planeta, cuja heterogeneidade de habitats, que varia na escala de nanômetros até quilômetros, abriga enorme biodiversidade que desempenha papel essencial para a continuida¬de dos

  15. A letra em seu devido lugar

    Directory of Open Access Journals (Sweden)

    Musso Garcia Greco

    2005-12-01

    Full Text Available A oficina de letras (letra, segundo Lacan busca criar um ponto de ancoragem para o sujeito psicótico, desconstruindo seu saber absoluto, através da articulação literatura e psicanálise, em sua função metonímica.

  16. Biodiversidade do solo em ecossistemas brasileiros

    NARCIS (Netherlands)

    Moreira, F.M.S.; Siqueira, J.O.; Brussaard, L.

    2008-01-01

    Biodiversidade do Solo em Ecossistemas Brasileiros R,00 O solo é considerado o ecossistema mais complexo e dinâmico do planeta, cuja heterogeneidade de habitats, que varia na escala de nanômetros até quilômetros, abriga enorme biodiversidade que desempenha papel essencial para a continuida¬de dos pr

  17. Supercritical Fluid Extraction of <em>Eucalyptus globulusem> Bark—A Promising Approach for Triterpenoid Production<em>>

    Directory of Open Access Journals (Sweden)

    Carlos M. Silva

    2012-06-01

    Full Text Available Eucalyptus bark contains significant amounts of triterpenoids with demonstrated bioactivity, namely triterpenic acids and their acetyl derivatives (ursolic, betulinic, oleanolic, betulonic, 3-acetylursolic, and 3-acetyloleanolic acids. In this work, the supercritical fluid extraction (SFE of <em>Eucalyptus> <em>globulus> deciduous bark was carried out with pure and modified carbon dioxide to recover this fraction, and the results were compared with those obtained by Soxhlet extraction with dichloromethane. The effects of pressure (100–200 bar, co-solvent (ethanol content (0, 5 and 8% wt, and multistep operation were studied in order to evaluate the applicability of SFE for their selective and efficient production. The individual extraction curves of the main families of compounds were measured, and the extracts analyzed by GC-MS. Results pointed out the influence of pressure and the important role played by the co-solvent. Ethanol can be used with advantage, since its effect is more important than increasing pressure by several tens of bar. At 160 bar and 40 °C, the introduction of 8% (wt of ethanol greatly improves the yield of triterpenoids more than threefold.

  18. EMS – Elektron Musik Studion in Stockholm

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

    2016-01-01

    In 1964 the electronic music studio EMS, Stockholm opened as a conventional analogue studio. The primary intension with the institution was to build the world’s most advanced hybrid studio and to conduct an international research program into sound and sound perception. With financial support from...

  19. Desenvolvimento puberal em meninas tratadas de LLA

    Directory of Open Access Journals (Sweden)

    Monteiro I.M.M.

    1998-01-01

    Full Text Available OBJETIVO: Com o objetivo de avaliar o desenvolvimento puberal após o tratamento de leucemia linfóide aguda (LLA na infância, foi realizado um estudo retrospectivo, em meninas tratadas de janeiro de 1980 a janeiro de 1991, no Centro de Investigações Hematológicas "Dr. Domingos A. Boldrini", em Campinas-SP. CASUÍSTICA E MÉTODO: Foram selecionadas 42 meninas, tratadas antes da puberdade com quimioterapia sistêmica e intratecal e radioterapia cranial, utilizando doses de 18 ou 24 Grays (Gy. RESULTADOS: As idades médias da telarca, pubarca e menarca foram inferiores às do grupo-controle, embora com significância estatística apenas para a idade da telarca. Não houve diferenças entre os grupos tratados com 18 ou 24Gy. As meninas tratadas antes dos cinco anos de idade apresentaram idade média da menarca estatisticamente inferior àquelas tratadas após cinco anos e em relação ao grupo-controle. CONCLUSÃO: Os resultados mostraram que o desenvolvimento puberal em meninas tratadas de LLA na infância foi mais precoce que o de meninas saudáveis.

  20. Enrichment and Purification of Syringin, Eleutheroside E and Isofraxidin from <em>Acanthopanax> <em>senticosus> by Macroporous Resin

    Directory of Open Access Journals (Sweden)

    Yuangang Zu

    2012-07-01

    Full Text Available In order to screen a suitable resin for the preparative simultaneous separation and purification of syringin, eleutheroside E and isofraxidin from <em>Acanthopanax> <em>senticosus>, the adsorption and desorption properties of 17 widely used commercial macroporous resins were evaluated. According to our results, HPD100C, which adsorbs by the molecular tiers model, was the best macroporous resin, offering higher adsorption and desorption capacities and higher adsorption speed for syringin, eleutheroside E and isofraxidin than other resins. Dynamic adsorption and desorption tests were carried out to optimize the process parameters. The optimal conditions were as follows: for adsorption, processing volume: 24 BV, flow rate: 2 BV/h; for desorption, ethanol–water solution: 60:40 (v/v, eluent volume: 4 BV, flow rate: 3 BV/h. Under the above conditions, the contents of syringin, eleutheroside E and isofraxidin increased 174-fold, 20-fold and 5-fold and their recoveries were 80.93%, 93.97% and 93.79%, respectively.

  1. Toxin profiles of <em>Bacillus cereusem> occurring in high numbers in spontaneously fermented African locust beans (<em>Parkia biglobosaem>)

    DEFF Research Database (Denmark)

    Thorsen, Line; Azokpota, Paulin; Hansen, Bjarne Munk;

    of toxin genes related to food poisoning using PCR. Isolates harboring the emetic specific gene fragment EM1 where highly representative, being one out of ten isolates from afitin, one of one isolate from iru and five of eight isolates from sonru. Three of the isolates from afitin harbored the cytotoxin K...

  2. Qualidade de vida em pacientes coronariopatas

    Directory of Open Access Journals (Sweden)

    Maria Cecília Bueno Jayme Gallani

    2003-02-01

    Full Text Available Este estudo comparou as medidas de qualidade de vida (QV entre 49 sujeitos com infarto do miocárdio (IM e 27 com angina pectoris (AP, atendidos em ambulatório em um hospital universitário. Os dados foram obtidos por meio da aplicação de um questionário para levantamento de dados sociodemográficos e clínicos e do instrumento SF-36 para avaliação da QV. Constatou-se, em ambos os grupos, comprometimento da QV nas dimensões: aspectos físicos, dor, estado geral de saúde, vitalidade, aspectos sociais e saúde mental. Variáveis sociodemográficas e clínicas foram associadas com menores escores de QV em diferentes dimensões. Estudos futuros devem ser conduzidos, visando a ampliação do tamanho da amostra, e a compreensão da magnitude do efeito destas variáveis sobre a QV do coronariopata.

  3. First airborne transient em survey in antarctica

    DEFF Research Database (Denmark)

    Auken, Esben; Mikucki, J. J.; Sørensen, Kurt Ingvard K.I.

    2012-01-01

    A first airborne transient electromagnetic survey was flown in Antarctica in December 2011 with the SkyTEM system. This transient airborne EM system has been optimized in Denmark for almost ten years and was specially designed for ground water mapping. The SkyTEM tool is ideal for mapping...

  4. Badger <em>Meles melesem> and Fox <em>Vulpes vulpesem> food in agricultural land in the western Po Plain (Italy

    Directory of Open Access Journals (Sweden)

    Luca Canova

    1994-05-01

    Full Text Available Abstract Fox and badger diets were studied by means of scat analysis in agricultural land in northern Italy. Earthworms and corn were the staple food for the badger, while foxes fed mainly on animal food (birds and mammals. Dietary overlap between the two species was low. Fox diets were substantially similar to those in north-central Europe and other areas of Italy. Badger diets differed from those in mediterranean areas of Italy and were similar to diets of north European populations. Riassunto Alimentazione di Tasso <em>Meles melesem> e Volpe <em>Vulpes vulpesem> in aree agricole della Pianura Padana occidentale - La dieta di tasso e volpe in un'area agricola della Pianura Padana occidentale è stata studiata mediante analisi delle feci. Lombrichi e mais rappresentano la principale fonte alimentare per il tasso, mentre la dieta della volpe è basata prevalentemente su uccelli e mammiferi. La sovrapposizione alimentare fra le due specie è ridotta. La dieta della volpe è simile a quella delle popolazioni dell'Europa centrale e settentrionale; la dieta del tasso differisce nettamente da quella delle popolazioni italiane che vivono in ambiente mediterraneo.

  5. Melanogenesis Inhibition by Homoisoflavavone Sappanone A from <em>Caesalpinia sappanem>

    Directory of Open Access Journals (Sweden)

    Hsiou-Yu Ding

    2012-08-01

    Full Text Available Homoisoflavanone, sappanone A, was isolated from <em>Caesalpinia sappanem> and proven to dose-dependently inhibit both melanogenesis and cellular tyrosinase activity via repressing tyrosinase gene expression in mouse B16 melanoma cells. To our knowledge, sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. Our results give a new impetus to the future search for other homoisoflavanone melanogenesis inhibitors.

  6. New Antifungal Pyranoisoflavone from <em>Ficus tikoua em>Bur.

    Directory of Open Access Journals (Sweden)

    Shaopeng Wei

    2012-06-01

    Full Text Available Considering the undesirable attributes of synthetic fungicides and the availability of Ficus<em> em>species in China, the stem of<em> Ficus tikoua em>Bur. was investigated. One new antifungal pyranoisoflavone, 5,3',4'-trihydroxy-2",2"-dimethylpyrano (5",6":7,8 isoflavone (1, together with two known isoflavones, wighteone (2 and lupiwighteone (3 (with previously reported antifungal activities, were isolated from ethyl acetate extract by bioassay-guided fractionation. Their structures were determined by spectroscopic analysis, such as NMR (1H-1H COSY, HMQC, HMBC and NOESY, IR, UV and HRMS, as well as ESI-MSn analyses. The antifungal activities of 13 against <em>Phytophthora infestansem> were evaluated by direct spore germination assay, and the IC50 values were 262.442, 198.153 and 90.365 µg·mL−1, respectively.

  7. Acetylcholinesterase-Inhibiting Activity of Salicylanilide <em>N>-Alkylcarbamates and Their Molecular Docking

    Directory of Open Access Journals (Sweden)

    Josef Jampilek

    2012-08-01

    Full Text Available A series of twenty-five novel salicylanilide <em>N>-alkylcarbamates were investigated as potential acetylcholinesterase inhibitors. The compounds were tested for their ability to inhibit acetylcholinesterase (AChE from electric eel (<em>Electrophorus electricusem> L.. Experimental lipophilicity was determined, and the structure-activity relationships are discussed. The mode of binding in the active site of AChE was investigated by molecular docking. All the discussed compounds expressed significantly higher AChE inhibitory activity than rivastigmine and slightly lower than galanthamine. Disubstitution by chlorine in C'(3,4 of the aniline ring and the optimal length of hexyl-undecyl alkyl chains in the carbamate moiety provided the most active AChE inhibitors. Monochlorination in C'(4 exhibited slightly more effective AChE inhibitors than in C'(3. Generally it can be stated that compounds with higher lipophilicity showed higher inhibition, and the activity of the compounds is strongly dependent on the length of the <em>N>-alkyl chain.

  8. Problematização do trabalho em equipe em enfermagem: relato de experiência

    Directory of Open Access Journals (Sweden)

    Marília Doriguello Bergamim

    2013-02-01

    Full Text Available Relato de experiência em relação ao trabalho em equipe, a partir da observação da realidade do estágio curricular em enfermagem. Realizou-se dinâmica de grupo com a equipe de enfermagem da clínica cirúrgica de um hospital público de São Paulo, com participação voluntária de oito auxiliares de enfermagem e utilizou-se, como base teórica, a Metodologia da Problematização, que objetiva a compreensão da realidade para nela intervir e transformá-la. Observou-se deficiência na autocrítica desses participantes, pois apontaram os problemas em relação ao trabalho em equipe sempre decorrentes da falta de cooperação de outros colegas, em detrimento de atitudes pessoais. Essa estratégia contribuiu de maneira significativa para a reflexão de comportamentos, atitudes, valores e crenças indispensáveis à formação do enfermeiro.

  9. Preliminary study on the acoustic communication of captive otters (<em>Lutra lutraem>

    Directory of Open Access Journals (Sweden)

    Claudio Gnoli

    1995-12-01

    Full Text Available Abstract The study was conducted on captive otters (<em>Lutra lutraem> in a large enclosure (1.64 ha in area. Data on different kind of sounds related to specific behaviours were recorded by videocamera. Furthermore, sounds were collected by tape recorder, analysed by spectrograph and represented by spectrograms. A general pattern of the vocalizations of otter has been obtained, in order to understand the acoustic communication system of the species. The main sound categories were blows, mewings and cries in an aggressive context, murmurs and two kinds of whistles in a social context. Riassunto Studio preliminare sulla comunicazione acustica della lontra (<em>Lutra lutraem> in cattività - Lo studio è stato condotto su lontre (<em>Lutra lutraem> tenute in cattività in un ampio recinto (1,64 ha. Attraverso riprese effettuate tramite videocamera, sono stati raccolti dati sull'emissione delle diverse tipologie di suoni in determinati contesti comportamentali. Inoltre, per mezzo di un magnetofono sono state registrate alcune manifestazioni sonore, successivamente analizzate mediante sonografo e rappresentate in forma di spettrogrammi. In questo modo è stato ottenuto un quadro della gamma di vocalizzazioni della lontra che può contribuire alla comprensione del suo sistema di comunicazione acustica. Le principali categorie di suoni individuate consistono in sbuffi, miagolii e grida nell'ambito aggressivo, mormorii e due tipi di fischi nell'ambito del contatto sociale.

  10. A new karyotype of <em>Calomyscus> from the Khorasan Province, Iran

    Directory of Open Access Journals (Sweden)

    Esmaeeli Somayeh

    2008-07-01

    Full Text Available Abstract We report a new karyotype of <em>Calomyscus> from two localities of the Khorasan Province (Aghdarband, 36° 11’ 3”N, 60° 44’ 6” E and Khajemorad, 36° 8’ 5” N, 59° 41’ 58” E. Chromosomes were examined by conventional staining and C-banding techniques. The diploid chromosome number (2n and the fundamental autosomal arm number (FNa were 44 and 60 respectively. The autosomal set consisted of 12 pairs of telocentrics, 5 pairs of acrocentrics and 4 pairs of sub-metacentrics. Both heterosomes were small telocentrics. Riassunto Un nuovo cariotipo del genere <em>Calomyscus> dalla provincia di Khorasan, Iran. Si descrive un nuovo cariotipo appartenente al genere <em>Calomyscus>, scoperto in due località della provincia di Khorasan (Aghdarband, 36° 11’ 3”N, 60° 44’ 6” E e Khajemorad, 36° 8’ 5” N, 59° 41’ 58” E. I cromosomi sono stati analizzati con le tecniche standard di colorazione e bandeggio. Il numero diploide di cromosomi (2n e il numero fondamentale di bracci autosomici sono risultati pari a 44 e 60 rispettivamente. Il set di cromosomi autosomici è composto da 12 paia di telocentrici, 5 di acrocentrici e 4 di sub-metacentrici. Entrambi i cromosomi sessuali si presentano come piccoli telocentrici.

  11. Uso de digital em idosos admitidos em unidade de geriatria de um hospital geral

    Directory of Open Access Journals (Sweden)

    Cunha Ulisses Gabriel de Vasconcelos

    1998-01-01

    Full Text Available OBJETVO: Detectar a freqüência da prescrição do digital, assim como as suas indicações, em idosos admitidos em unidade de geriatria de um hospital geral. MÉTODOS: Foram investigados, consecutivamente, 130 pacientes não selecionados, de ambos os sexos (100 mulheres e 30 homens, com idades > ou = 65 (média 80±9 anos. Os pacientes foram avaliados através de exame clínico completo, rotina básica de sangue, radiografia simples de tórax, eletrocardiograma e ecocardiograma Doppler. Baseados na avaliação clínica e exames complementares, o uso do digital foi considerado adequado, questionável ou inadequado. RESULTADOS: Estavam em uso de digital 27,6% dos pacientes. A indicação foi considerada adequada em 36,1%, questionável em 11,1% e inadequada em 52,7%. CONCLUSÃO: Uma alta prevalência de prescrição do digital foi detectada nos idosos admitidos, sendo que a maior parte a adotava por razões consideradas inadequadas ou questionáveis. Devido ao risco aumentado de intoxicação digitálica nessa faixa etária, a droga deveria ser prescrita sob indicações mais criteriosas.

  12. Splitting longitudinal-transversal em uma microcavidade semicondutora

    OpenAIRE

    Victor Schmidt Comitti

    2013-01-01

    Neste trabalho investigamos um desdobramento de aproximadamente 0,19 meV no espectro de luminescência do Lower Polariton (LP) em uma microcavidade semicondutora de espessura com um poço quântico de GaAs imerso. Existem algumas causas possíveis para o desdobramento em energia do LP em uma microcavidade. Ao longo da dissertação citamos as principais e, em seguida, tentamos demonstrar por um método de eliminação de hipóteses, baseado em medidas de fotoluminescência, que o fenômeno observado é o...

  13. Babesiose cerebral em bovinos: 20 casos

    Directory of Open Access Journals (Sweden)

    Rodrigues Aline

    2005-01-01

    Full Text Available Num estudo retrospectivo de 1.071 necropsias de bovinos, foram encontrados 20 casos de babesiose cerebral confirmados pelo exame de esfregaços do córtex telencefálico. A maioria desses casos ocorreu no verão, em bovinos adultos de raças européias ou suas cruzas. Além dos sinais clínicos neurológicos, observou-se hemoglobinúria, anorexia, febre, taquicardia, taquipnéia e queda na produção de leite. O hemograma realizado em cinco bovinos afetados revelou acentuada anemia regenerativa; em média, 20% dos eritrócitos estavam parasitados por Babesia bovis. Na necropsia de todos os casos, a substância cinzenta dos córtices telencefálico e cerebelar e dos núcleos da base era consistente e caracteristicamente róseo-cereja. Essa coloração devia-se ao seqüestro de eritrócitos nos capilares encefálicos. Nesses eritrócitos, podiam-se observar, tanto em esfregaços do córtex como em preparações histológicas do encéfalo, microorganismos com morfologia compatível com B. bovis. Outros achados de necropsia incluíam hemoglobinúria, rins vermelho-escuros, hepatoesplenomegalia, fígado vermelho-alaranjado, icterícia, hemorragias epicárdicas e endocárdicas e edema e congestão dos linfonodos mesentéricos.

  14. Regional EM studies in the 80's

    Science.gov (United States)

    Hjelt, S. E.

    1987-09-01

    The review describes in broad terms the development of regional EM studies during the last five-six years. Large simultaneous magnetometer arrays, broadband and dense profiling with five component instruments, the use of remote reference techniques and in-field data processing have increased both the number and the quality of EM surveys. The increase has been strong all over the world. An extensive list of references, divided geographically, is presented. Selected examples of regional resisitivity-versus-depth curves are shown for Africa, the Baikal region, the Baltic Shield, the Canadian Shield, the Carpathian regions, the Central Andes, Iceland, India, the Juan de Fuca Plate, the Münsterland Basin, the Rio Grande rift, the Scottish Caledonides, the Tasman Sea, and for the United States in general. Because of the influence of tectonic settings and the metamorphic grade of rocks, only qualitative aspects of the results are relevant. ‘Classical’ array studies, especially in Australia, in the Carpathian regions, in India, in North Germany and in Scotland have been reinterpreted and completed with more accurate 2D modelling and dense MT profiling. In the USA and Canada also new regions have been surveyed extensively. New regional EM work has been conducted extensively on the Baltic Shield and in Central and North Africa, Siberia, China, in the areas around the Caspian and Black Seas and in South America. The newest studies are supported by or compared with other geophysical data, which also are used in extrapolating for missing EM data density. There are several successful large-scale projects in operation: the European Geotraverse (EGT), the KAPG International Geotraverses and the EMSLAB project (with its first preliminary results). Regional EM studies have been increasingly applied to geothermal, hydrocarbon and mineral prospecting as well as local structural studies, e.g. studies of sites for nuclear waste disposal.

  15. Cartilagem tragal com pericondrio em timpanoplastias

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    Testa José Ricardo Gurgel

    2002-01-01

    Full Text Available Introdução: os enxertos de cartilagem começaram a ser usados por Jansen em 1963 que sugeriu que teriam sua indicação em casos mais avançados por ser mais rígido resistindo melhor à reabsorções e retrações. Em 1998 Eavey descreve o uso de cartilagem tragal com pericôndrio bilateral e a sua colocação sem incisões no meato acústico externo. Forma de estudo: clínico prospectivo randomizado. material e método: Foram estudados 100 pacientes portadores de seqüelas de otites médias crônicas, com perfurações da membrana timpânica com rebordo e submetidos a timpanoplastias com cartilagem tragal e pericôndrio. As dimensões das perfurações foram em média 40% da área da membrana timpânica. Na avaliação auditiva observamos média pré-operatória de perda condutiva de 28.3 dB e pós-operatória de 9.8 dB. Resultados: O fechamento da perfuração foi total em 95.0% dos casos. Conclusão: Estudando os resultados concluímos que o método é de fácil realização, com poucas complicações, bons resultados auditivos e ótimos resultados anatômicos. Sendo uma ótima opção para o otologista na resolução das seqüelas das otites crônicas.

  16. Tela em branco: cinema da origem,origem do cinema

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    André Brasil

    2009-06-01

    Full Text Available Por meio da tela em branco que aparece em três filmes (Zen for film, de Nam June Paik, Scénario du film Passion, de Jean-Luc Godard, e Onde jaz o teu sorriso?, de Pedro Costa e em um projeto fotográfico (Theatres, de Hiroshi Sugimoto, abordamos o conceito de origem na perspectiva de Walter Benjamin. Em sua abertura e inacabamento, a origem só pode se restituir no futuro, por um trabalho da memória, que se define como recriação a partir de vestígios da história. Aqui se busca um cinema da origem (diferente de um cinema das origens, em cujo saber se abriga sempre um não-saber originário. Nós o encontraremos na tela em branco, nos modos diversos como ela surge em cada uma destas obras.

  17. On the occurrence of <em>Myotis alcathoeem> von Helversen and Heller, 2001 in Austria

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    Friederike Spitzenberger

    2008-07-01

    Full Text Available Abstract In 2006, one male and two females of <em>Myotis alcathoeem> were captured in mistnets at two localities in southern Burgenland, Austria. For two individuals the preliminary specific identification based on external measurements was confirmed by sequencing parts of the mitochondrial ND1 gene. Across the sequenced region, the two analysed bats share a 100% identical haplotype that corresponds to the haplotype found in Hungarian bats identified as <em>M. alcathoeem>, and was found also in Spanish, French and Slovakian samples. The three animals from Burgenland constitute the first records of this species in Austria. Age related differences in pelage and membrane colouration and measurements of <em>M. alcathoeem> are described. A comparison of skull length measurements between <em>M. alcathoeem> and <em>Myotis mystacinusem> seems to indicate that the interspecific difference in external dimensions is not reflected in skull dimensions. The Austrian localities of <em>M. alcathoeem> belong to the Pannonian part of the range like findings in Slovakia and Hungary. Riassunto Sulla presenza di <em>Myotis alcathoeem> von Helversen and Heller, 2001 in Austria. Nel 2006, due maschi e una femmina di <em>Myotis alcathoeem> sono stati catturati tramite mist-nets in due località del Burgenland meridionale, Austria. Per due individui, l’identificazione preliminare su basi morfologiche è stata confermata dall’analisi del gene mitocondriale ND1. Nella sequenza analizzata, gli aplotipi dei due individui coincidono al 100% e corrispondono a quelli evidenziati in soggetti spagnoli, francesi e sloveni. I tre esemplari del Burgenland rappresentano la prima segnalazione certa di questa specie per l’Austria. Vengono descritte alcune differenze nella colorazione della pelliccia e del patagio tra adulti e subadulti. Il confronto delle misure del cranio di <em>M. alcathoeem> e <em

  18. Sorteio de domicílios em favelas em inquéritos por amostragem

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    Maria Cecilia Goi Porto Alves

    2011-12-01

    Full Text Available OBJETIVO: Identificar vantagens e desvantagens do uso de segmentos em relação ao sorteio feito a partir da lista completa de endereços, para o sorteio de domicílios em amostragem por conglomerados em múltiplos estágios em favelas. PROCEDIMENTOS METODOLÓGICOS: Estudo qualitativo realizado em quatro favelas sorteadas no Inquérito de Saúde do Município de São Paulo, SP, 2008, nas quais foram aplicadas as duas técnicas. Foram realizados grupos focais com pesquisadores de campo - "arroladores" e entrevistadores do inquérito. Os conteúdos das conversações foram analisados, agrupados em categorias e organizados em núcleos temáticos. ANÁLISE DOS RESULTADOS: A utilização de segmentos de domicílios foi associada a numerosas vantagens e poucas desvantagens. Entre as vantagens, constaram a rapidez e facilidade na elaboração do cadastro de endereços e na localização e identificação de domicílios na etapa de realização das entrevistas, maior segurança dos entrevistadores e da população, maior acesso aos entrevistados, maior estabilidade e maior cobertura do cadastro produzido, e menor ocorrência de erros na identificação dos domicílios sorteados. CONCLUSÕES: A construção de cadastro de domicílios por meio da criação de segmentos é vantajosa em relação à listagem completa de endereços, quando feita em favelas. Por ter se mostrado uma opção econômica e fácil de ser aplicada, constitui alternativa para a simplificação do processo de amostragem em áreas com as suas características de desorganização e adensamento de domicílios.

  19. Evaluation of Antioxidant and Immunity-Enhancing Activities of <em>Sargassum pallidumem> Aqueous Extract in Gastric Cancer Rats

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    Shen-Kang Zhou

    2012-07-01

    Full Text Available The effect of <em>Sargassum pallidumem> (brown seaweed aqueous extract on the immunity function and antioxidant activities in was studied gastric cancer rats. Treatment with <em>Sargassum pallidumem> aqueous extract at oral doses 400, 600 or 800 mg/kg body weight was found to provide a dose-dependent protection against <em>Nem>-methyl-N′-nitro-N>-nitrosoguanidine (MNNG-induced immunity damage and oxidative injury by enhancing serum interleukin-2 (IL-2, interleukin-4 (IL-4, interleukin-10 (IL-10 levels, decreasing interleukin-6 (IL-6, interleukin-1β (IL-1β, tumor necrosis factor-alpha (TNF-α levels, preserving normal antioxidant enzymes activities, and by inhibiting lipid peroxidation in gastric mucosa. It can be concluded that <em>Sargassum pallidumem> aqueous extract may enhance the immunity and antioxidant activities in gastric cancer rats.

  20. The association between EMS workplace safety culture and safety outcomes.

    Science.gov (United States)

    Weaver, Matthew D; Wang, Henry E; Fairbanks, Rollin J; Patterson, Daniel

    2012-01-01

    Prior studies have highlighted wide variation in emergency medical services (EMS) workplace safety culture across agencies. To determine the association between EMS workplace safety culture scores and patient or provider safety outcomes. We administered a cross-sectional survey to EMS workers affiliated with a convenience sample of agencies. We recruited these agencies from a national EMS management organization. We used the EMS Safety Attitudes Questionnaire (EMS-SAQ) to measure workplace safety culture and the EMS Safety Inventory (EMS-SI), a tool developed to capture self-reported safety outcomes from EMS workers. The EMS-SAQ provides reliable and valid measures of six domains: safety climate, teamwork climate, perceptions of management, working conditions, stress recognition, and job satisfaction. A panel of medical directors, emergency medical technicians and paramedics, and occupational epidemiologists developed the EMS-SI to measure self-reported injury, medical errors and adverse events, and safety-compromising behaviors. We used hierarchical linear models to evaluate the association between EMS-SAQ scores and EMS-SI safety outcome measures. Sixteen percent of all respondents reported experiencing an injury in the past three months, four of every 10 respondents reported an error or adverse event (AE), and 89% reported safety-compromising behaviors. Respondents reporting injury scored lower on five of the six domains of safety culture. Respondents reporting an error or AE scored lower for four of the six domains, while respondents reporting safety-compromising behavior had lower safety culture scores for five of the six domains. Individual EMS worker perceptions of workplace safety culture are associated with composite measures of patient and provider safety outcomes. This study is preliminary evidence of the association between safety culture and patient or provider safety outcomes.