WorldWideScience

Sample records for super urgent transplantation

  1. Super obese 33-week parturient undergoing an urgent laparoscopic bowel resection: A case report and review of anesthetic implications

    Directory of Open Access Journals (Sweden)

    Yury Khelemsky

    2011-01-01

    Full Text Available Approximately two percent of women undergo non-obstetric surgery during their pregnancies. The following case report describes the anesthetic management of a super obese parturient in her third trimester of pregnancy undergoing urgent laparoscopic (converted to open bowel resection. Such a case, which has not been previously reported, has multiple clinical implications for both mother and fetus and was further complicated by super obesity (BMI>50 and laparoscopy. The anesthetic implications for this patient population are reviewed.

  2. Two-stage liver transplantation: an effective procedure in urgent conditions.

    Science.gov (United States)

    Montalti, Roberto; Busani, Stefano; Masetti, Michele; Girardis, Massimo; Di Benedetto, Fabrizio; Begliomini, Bruno; Rompianesi, Gianluca; Rinaldi, Laura; Ballarin, Roberto; Pasetto, Alberto; Gerunda, Giorgio E

    2010-01-01

    Temporary portocaval shunt and total hepatectomy is a technique used in the presence of toxic liver syndrome because of fulminant hepatic failure, hepatic trauma, primary non-function (PNF), and eclampsia. We performed this technique on four patients. An indication for anhepatic state was severe hemodynamic instability in three of them. Etiologies of these three patients were as follows: PNF after liver transplantation, ischemic hepatitis after right hepatic artery embolization, and massive reperfusion syndrome during a liver transplantation. In the fourth patient, during the liver transplantation when hepatic artery was ligated, a kidney carcinoma in the donor graft was discovered. We decided to complete the hepatectomy and to construct a temporary portocaval shunt. Mean anhepatic phases were 19 h and 15 min. All patients survived the two-stage liver transplantation procedure without major complications. Our cases demonstrated that temporary portocaval shunt while awaiting urgent liver transplantation could be an effective "bridge" in selected patients who develop toxic liver syndrome; however, a short time between portocaval shunt and transplantation and careful intensive care managements are mandatory.

  3. A single German center experience with intermittent inotropes for patients on the high-urgent heart transplant waiting list.

    Science.gov (United States)

    Hübner, T; Nickel, T; Steinbeck, G; Massberg, S; Schramm, R; Reichart, B; Hagl, C; Kiwi, A; Weis, Michael

    2015-11-01

    Currently, more than 900 patients with end-stage heart failure are listed for heart transplantation in Germany. All patients on the Eurotransplant high-urgent status (HU) have to be treated in intensive care units and have to be relisted every 8 weeks. Long-term continuous inotropes are associated with tachyphylaxia, arrhythmias and even increased mortality. In this retrospective analysis, we report our single center experience with HU patients treated with intermittent inotropes as a bridging therapy. 117 consecutive adult HU candidates were treated at our intensive care heart failure unit between 2008 and 2013, of whom 14 patients (12 %) were stabilized and delisted during follow-up. In the remaining 103 patients (age 42 ± 15 years), different inotropes (dobutamine, milrinone, adrenaline, noradrenaline, levosimendan) were administered based on the patient's specific characteristics. After initial recompensation, patients were weaned from inotropes as soon as possible. Thereafter, intermittent inotropes (over 3-4 days) were given as a predefined weekly (until 2011) or 8 weekly regimen (from 2011 to 2013). In 57 % of these patients, additional regimen-independent inotropic support was necessary due to hemodynamic instabilities. Fourteen patients (14 %) needed a left- or biventricular assist device; 14 patients (14 %) died while waiting and 87 (84 %) received heart transplants after 87 ± 91 days. Cumulative 3 and 12 months survival of all 103 patients was 75 and 67 %, respectively. Intermittent inotropes in HU patients are an adequate strategy as a bridge to transplant; the necessity for assist devices was low. These data provide the basis for a prospective multicenter trial of intermittent inotropes in patients on the HU waiting list.

  4. A simplified way for the urgent treatment of somatic pain in patients admitted to the emergency room: the SUPER algorithm.

    Science.gov (United States)

    Franceschi, Francesco; Marsiliani, Davide; Alesi, Andrea; Mancini, Maria Grazia; Ojetti, Veronica; Candelli, Marcello; Gabrielli, Maurizio; D'Aurizio, Gabriella; Gilardi, Emanuele; Adducci, Enrica; Proietti, Rodolfo; Buccelletti, Francesco

    2015-12-01

    Somatic pain is one of the most frequent symptoms reported by patients presenting to the emergency department (ED), but, in spite of this, it is very often underestimated and under-treated. Moreover, pain-killers prescriptions are usually related to the medical examination, leading to a delay in its administration, thus worsening the patient's quality of life. With our study, we want to define and validate a systematic and homogeneous approach to analgesic drugs administration, testing a new therapeutic algorithm in terms of earliness, safety, and efficacy. 442 consecutive patients who accessed our ED for any kind of somatic pain were enrolled, and then randomly divided into two groups: group A follow the normal process of access to pain-control drugs, and group B follow our SUPER algorithm for early administration of drugs to relieve pain directly from triage. We excluded from the study, patients with abdominal pain referred to the surgeon, patients with headache, recent history of trauma, history of drug allergies, and life-threatening conditions or lack of cooperation. Drugs used in the study were those available in our ED, such as paracetamol, paracetamol/codeine, ketorolac-tromethamine, and tramadol-hydrochloride. Pain level, risk factors, indication, and contraindication of each drug were taken into account in our SUPER algorithm for a rapid and safe administration of it. The Verbal Numeric Scale (VNS) and the Visual Analog Scale (VAS) were used to verify the patient's health and perception of it. Only 59 patient from group A (27.1 %) received analgesic therapy (at the time of the medical examination) compared to 181 patients (100 %) of group B (p pain-control therapy directly from triage is safe and effective, and significantly improves patients perceptions of their own health.

  5. A staged approach for a lung-liver transplant patient using ex vivo reconditioned lungs first followed by an urgent liver transplantation

    NARCIS (Netherlands)

    Van De Wauwer, Caroline; Verschuuren, Erik A. M.; Nossent, George D.; van der Bij, Wim; den Hamer, Inez J.; Klinkenberg, Theo J.; van den Berg, Aad P.; de Boer, Marieke T.; Mariani, Massimo A.; Erasmus, Michiel E.

    Combined lung-liver transplantation is a logistically challenging procedure hampered by shortage of organ donors. We describe the case of a young patient with end-stage lung disease due to of cystic fibrosis and liver cirrhosis who needed combined lung-liver transplantation. The long waiting for

  6. Direct thrombolysis of multiple thrombi in both right and left heart atrium in a patient on extracorporeal membrane oxygenation support following urgent double-lung transplantation: a case report

    Directory of Open Access Journals (Sweden)

    Pollert L

    2016-06-01

    Full Text Available Lukas Pollert,1 Zuzana Prikrylova,1 Jan Berousek,1 Frantisek Mosna,1 Robert Lischke2 1Department of Anaesthesiology and Intensive Care, 2nd Faculty of Medicine, 23rd Surgical Department, 1st Faculty of Medicine, Charles University in Prague and Motol University Hospital, Praha, Czech Republic Background: Lung transplantation is considered an established treatment for patients with end-stage chronic respiratory failure. Patients with acute respiratory failure requiring respiratory support with invasive mechanical ventilation while awaiting lung transplantation are at high risk of death. Extracorporeal membrane oxygenation (ECMO has been proposed as an alternative bridging strategy to mechanical ventilation. The shear stress created by the mechanical pumps causes changes in the hematological system in almost all patients treated with ECMO. An antithrombotic strategy to mitigate ECMO bleeding and thrombotic complications is necessary. The use of thrombolytic therapy is recommended for patients with acute symptomatic embolism with associated hypotension or shock. In this setting, the hemodynamic benefits of thrombolytic treatment far outweigh its bleeding risk.Case presentation: This case report describes a 32-year-old woman suffering from lymphangioleiomyomatosis, who underwent urgent double-lung transplantation. This patient was maintained on ECMO preoperatively, perioperatively, and postoperatively due to life-threatening hypoxemia caused by the progression of her pulmonary tissue damage. Multiple thrombi developed in the early postoperative period, in both right and left heart atria. Direct thrombolysis was successfully performed on the first postoperative day.Conclusion: According to the current published literature, direct thrombolysis of thrombi in both right and left atria in a patient supported on ECMO following urgent double-lung transplantation is an extremely rare treatment method. Even when taking into account all of the risks

  7. [Response of yield, quality and nitrogen use efficiency to nitrogen fertilizer from mechanical transplanting super japonica rice].

    Science.gov (United States)

    Wei, Hai-Yan; Wang, Ya-Jiang; Meng, Tian-Yao; Ge, Meng-Jie; Zhang, Hong-Cheng; Dai, Qi-Gen; Huo, Zhong-Yang; Xu, Ke

    2014-02-01

    Five super japonica rice cultivars were grown by mechanical transplanting in field and seven N treatments with total N application rate of 0, 150, 187.5, 225, 262.5, 300 and 337.5 kg x hm(-2) respectively were adopted to study the effects of N rate on rice yield, quality and N use efficiency. The differences between N requirement for obtaining the highest yield and for achieving the best economic benefit were compared. With the increase of N fertilizer rate, the yields of five super japonica rice cultivars increased firstly and then descended, achieving the highest yield at the N level of 300 kg x hm(-2) ranging from 10.33-10.60 kg x hm(-2). Yield increase mainly attributed to the large number of spikelet, for the total spikelet number of each rice cultivar reached the maximum value at the 300 kg x hm(-2) N level. With the increase of N application, the rates of brown rice, milled rice, head milled rice and the protein content of the five super japonica rice cultivars were all increased, and the rates of brown rice, milled rice, head milled rice and the protein con- tent were higher at 337.5 kg x hm(-2) N level than at 0 kg x hm(-2) N level by 3.3%-4.2%, 2.9%-6.0%, 4.4%-33.7% and 23.8%-44.3%, respectively. While the amylose content, gel consistency and taste value of the five rice cultivars were all decreased, and the amylose content, gel consistency and taste value were lower at 337.5 kg x hm(-2) N level than at 0 kg x hm(-2) N level by 12.4%-38.9%, 10.3%-28.5% and 20.3%-29.7%, respectively. The chalkiness increased firstly and then decreased while the change of chalky rate varied with the cultivars. With the increase of N application, the N use efficiency, agronomic N use efficiency and physiological N use efficiency decreased while the N uptake of grain increased significantly. If the cost of N fertilizer was taken into account, the N fertilizer amount to obtain the optimal economic benefits would be 275.68 kg x hm(-2) with the corresponding yield of 9.97 t x hm

  8. TRANSPLANTATION

    African Journals Online (AJOL)

    Kidney transplantation remains the treatment of choice ... evidence that transplantation improves both the quality and ... institutions, resulting in less postoperative pain, a shorter ... percutaneous intervention was required as there were no.

  9. Allogeneic Bone Marrow Transplant from MRL/MpJ Super-Healer Mice Does Not Improve Articular Cartilage Repair in the C57Bl/6 Strain.

    Directory of Open Access Journals (Sweden)

    Catherine A Leonard

    Full Text Available Articular cartilage has been the focus of multiple strategies to improve its regenerative/ repair capacity. The Murphy Roths Large (MRL/MpJ "super-healer" mouse demonstrates an unusual enhanced regenerative capacity in many tissues and provides an opportunity to further study endogenous cartilage repair. The objective of this study was to test whether the super-healer phenotype could be transferred from MRL/MpJ to non-healer C57Bl/6 mice by allogeneic bone marrow transplant.The healing of 2mm ear punches and full thickness cartilage defects was measured 4 and 8 weeks after injury in control C57Bl/6 and MRL/MpJ "super-healer" mice, and in radiation chimeras reconstituted with bone marrow from the other mouse strain. Healing was assessed using ear hole diameter measurement, a 14 point histological scoring scale for the cartilage defect and an adapted version of the Osteoarthritis Research Society International scale for assessment of osteoarthritis in mouse knee joints.Normal and chimeric MRL mice showed significantly better healing of articular cartilage and ear wounds along with less severe signs of osteoarthritis after cartilage injury than the control strain. Contrary to our hypothesis, however, bone marrow transplant from MRL mice did not confer improved healing on the C57Bl/6 chimeras, either in regards to ear wound healing or cartilage repair.The elusive cellular basis for the MRL regenerative phenotype still requires additional study and may possibly be dependent on additional cell types external to the bone marrow.

  10. MEDICAL SERVICE - URGENT CALLS

    CERN Multimedia

    Service Médical

    2000-01-01

    IN URGENT NEED OF A DOCTOR GENEVA: EMERGENCY SERVICES GENEVA AND VAUD 144 FIRE BRIGADE 118 POLICE 117 CERN FIREMEN 767-44-44 ANTI-POISONS CENTRE Open 24h/24h 01-251-51-51 Patient not fit to be moved, call family doctor, or: GP AT HOME: Open 24h/24h 748-49-50 AMG- Association Of Geneva Doctors: Emergency Doctors at home 07h-23h 322 20 20 Patient fit to be moved: HOPITAL CANTONAL CENTRAL 24 Micheli-du-Crest 372-33-11 ou 382-33-11 EMERGENCIES 382-33-11 ou 372-33-11 CHILDREN'S HOSPITAL 6 rue Willy-Donzé 372-33-11 MATERNITY 32 bvd.de la Cluse 382-68-16 ou 382-33-11 OPHTHALMOLOGY 22 Alcide Jentzer 382-33-11 ou 372-33-11 MEDICAL CENTRE CORNAVIN 1-3 rue du Jura 345 45 50 HOPITAL DE LA TOUR Meyrin 719-61-11 EMERGENCIES 719-61-11 CHILDREN'S EMERGENCIES 719-61-00 LA TOUR MEDICAL CENTRE 719-74-00 European Emergency Call 112   FRANCE: EMERGENCY SERVICES 15 FIRE BRIGADE 18 POLICE 17 CERN FIREMEN AT HOME 00-41-22-767-44-44 ...

  11. Urgent recommendation. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, Masayuki [International Affairs and Safeguards Division, Atomic Energy Bureau, Science and Technology Agency, Tokyo (Japan)

    2000-12-01

    The Investigation Committee for Critical Accident at Uranium Processing Plant was founded immediately after the accident to investigate the cause of the accident and to establish measures to prevent the similar accident. On September 30, 1999 around 10:35, the Japan's first criticality accident occurred at JCO Co. Ltd. Uranium processing plant (auxiliary conversion plant) located at Tokai-mura Ibaraki-ken. The criticality continued on and off for approximately 20 hours after the first instantaneous criticality. The accident led the recommendation of tentative evacuation and sheltering indoors for residents living in the neighborhood. The serious exposure to neutrons happened to three workers. The dominant effect is dose due to neutrons and gamma rays from the precipitation tank. When the accident took place, three workers dissolved sequentially about 2.4 kg uranium powder with 18.8 % enrichment in the 10-litter bucket with nitric acid. The procedure of homogenization of uranium nitrate was supposed to be controlled using the shape-limited narrow storage column. Actually, however, the thick and large precipitation tank was used. As a result, about 16.6 kg of uranium was fed into the tank, which presumably caused criticality. The first notification by JCO was delayed and the following communication was not smooth. This led to the delay of correct understanding of the situation and made the initial proper response difficult, then followed by insufficient communication between the nation, prefecture, and local authority. Urgent recommendations were made on the following items; (1) Safety measures to be taken at the accident site, (2) health cares for residents and others, (3) Comprehensive safety securing at nuclear operators such as Establishment of the effective audit system, Safety education for employees and Qualification and licensing system, Safety related documents, etc. (4) Reconstruction of the government's safety regulations such as How safety

  12. TRANSPLANTATION

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    Objective: To explore the experience ofliver transpfantation in patients with terminalliver failure. Methods: From October 1991 toJuly 1995, 17 adults and 6 children underwentorthotopic liver transplantation. Preoperativediagnosis showed biliary atresia (n=5), Alagillesyndrome (n=1), primary biliary cirrhosis(n=2), cryptogenic cirrhosis (n=2), alcoholic

  13. The Effect of Seed Priming and Transplanting on Morphological Characteristics, Yield and Yield Components of SuperSweet Corn

    Directory of Open Access Journals (Sweden)

    matin haghighi khah

    2017-03-01

    Full Text Available Introduction Corn (Zea mays L. is the third most important cereal crop in the world after wheat and rice (Lashkari et al., 2011. Corn production has been extended in to the whole world during the course of the last century due to its compatibility. It has more diversity compare to other cereal. Many corn types are cultivated, including field corn, ornamental corn, popcorn, sweet corn and several different supersweet corns. Sweet corn, considered a vegetable, is a special type of corn with particular characteristics, such as sweet taste, thin pericarp and endosperm with delicate texture, and high nutritional value. It is destined exclusively for human consumption, in fresh form or in processed foods, whereas the straw can be used for silage after harvest (Santos et al., 2014. Sweet corn seeds germinate slowly and exhibit poor seedling vigour. Poor germination in sweet corn has been attributed to low seed vigour and susceptibility to seed and soilborne diseases (Ratin et al., 2006. Seed priming is the one of efficient method to improve germination and emergence. In addition, transplanting provides optimal environmental conditions for seed germination and avoids planting seeds in disease-contaminated soil (Khalid et al., 2012. Materials and methods To investigate the effect of seed priming and transplanting on morphological characteristics, yield and yield components of supersweet corn a series of greenhouse and field experiments were conducted in a factorial based design on a randomized complete block in 2013. This experiment was conducted in the greenhouse to determine the best seed priming treatments. The treatments were hydro priming, Poly ethylene glycol (6000 -0.4 and -0.8 MPa, Sodium Sulphate 0.1 and 0.5%, Zinc Sulphate 1 and 0.5%, Copper Sulphate 0.1 and 0.5% and Control for 36 hours. After that the seeds washed by distillated water and dried back in laboratory conditions. Then treated seeds were sown in trays that contained by cocopeatand

  14. Lung transplantation

    Science.gov (United States)

    Afonso, José Eduardo; Werebe, Eduardo de Campos; Carraro, Rafael Medeiros; Teixeira, Ricardo Henrique de Oliveira Braga; Fernandes, Lucas Matos; Abdalla, Luis Gustavo; Samano, Marcos Naoyuki; Pêgo-Fernandes, Paulo Manuel

    2015-01-01

    ABSTRACT Lung transplantation is a globally accepted treatment for some advanced lung diseases, giving the recipients longer survival and better quality of life. Since the first transplant successfully performed in 1983, more than 40 thousand transplants have been performed worldwide. Of these, about seven hundred were in Brazil. However, survival of the transplant is less than desired, with a high mortality rate related to primary graft dysfunction, infection, and chronic graft dysfunction, particularly in the form of bronchiolitis obliterans syndrome. New technologies have been developed to improve the various stages of lung transplant. To increase the supply of lungs, ex vivo lung reconditioning has been used in some countries, including Brazil. For advanced life support in the perioperative period, extracorporeal membrane oxygenation and hemodynamic support equipment have been used as a bridge to transplant in critically ill patients on the waiting list, and to keep patients alive until resolution of the primary dysfunction after graft transplant. There are patients requiring lung transplant in Brazil who do not even come to the point of being referred to a transplant center because there are only seven such centers active in the country. It is urgent to create new centers capable of performing lung transplantation to provide patients with some advanced forms of lung disease a chance to live longer and with better quality of life. PMID:26154550

  15. Urgent Abdominal Re-Explorations

    Directory of Open Access Journals (Sweden)

    Peskersoy Mustafa

    2006-04-01

    Full Text Available Abstract Background Treatment of a number of complications that occur after abdominal surgeries may require that Urgent Abdominal Re-explorations (UARs, the life-saving and obligatory operations, are performed. The objectives of this study were to evaluate the reasons for performing UARs, outcomes of relaparotomies (RLs and factors that affect mortality. Methods Demographic characteristics; initial diagnoses; information from and complications of the first surgery received; durations and outcomes of UAR(s performed in patients who received early RLs because of complicated abdominal surgeries in our clinic between 01.01.2000 and 31.12.2004 were investigated retrospectively. Statistical analyses were done using the chi-square and Fisher exact tests. Results Early UAR was performed in 81 out of 4410 cases (1.8%. Average patient age was 50.46 (13–81 years with a male-to-female ratio of 60/21. Fifty one (62.96% patients had infection, 41 (50.61% of them had an accompanying serious disease, 24 (29.62% of them had various tumors and 57 (70.37% patients were operated under emergency conditions during first operation. Causes of urgent abdominal re-explorations were as follows: leakage from intestinal repair site or from anostomosis (n:34; 41.97%; hemorrhage (n:15; 18.51%; intestinal perforation (n:8; 9.87%; intraabdominal infection or abscess (n:8; 9.87%; progressive intestinal necrosis (n:7; 8.64%; stomal complications (n:5; 6.17%; and postoperative ileus (n:4; 4.93%. Two or more UARs were performed in 18 (22.22% cases, and overall mortality was 34.97% (n:30. Interval between the first laparotomy and UAR averaged as 6.95 (1–20 days, and average hospitalization period was 27.1 (3–78 days. Mortality rate was found to be higher among the patients who received multiple UARs. The most common (55.5% cause of mortality was sepsis/multiple organ failure (MOF. The rates for common mortality and sepsis/MOF-dependent mortality that occured following UAR were

  16. URGENT NEED OF A DOCTOR

    CERN Multimedia

    Medical Service

    2001-01-01

    IN URGENT NEED OF A DOCTOR GENEVA EMERGENCY SERVICES GENEVA AND VAUD 144 FIRE BRIGAD 118 POLICE 117 CERN FIREMEN 767-44-44 ANTI-POISONS CENTRE Open 24h/24h 01-251-51-51 Patient not fit to be moved, call family doctor, or: GP AT HOME, open 24h/24h 748-49-50 Association Of Geneva Doctors Emergency Doctors at home 07h-23h 322 20 20 Patient fit to be moved: HOPITAL CANTONAL CENTRAL 24 Micheli-du-Crest 372-33-11 ou 382-33-11 EMERGENCIES 382-33-11 ou 372-33-11 CHILDREN'S HOSPITAL 6 rue Willy-Donzé 372-33-11 MATERNITY 32 bvd.de la Cluse 382-68-16 ou 382-33-11 OPHTHALMOLOGY 22 Alcide Jentzer 382-33-11 ou 372-33-11 MEDICAL CENTRE CORNAVIN 1-3 rue du Jura 345 45 50 HOPITAL DE LA TOUR Meyrin EMERGENCIES 719-61-11 URGENCES PEDIATRIQUES 719-61-00 LA TOUR MEDICAL CENTRE 719-74-00 European EmergencyCall 112 FRANCE EMERGENCY SERVICES 15 FIRE BRIGADE 18 POLICE 17 CERN FIREMEN AT HOME 00-41-22-767-44-44 ANTI-POISONS CENTRE Open 24h/24h 04-72-11-69-11 All doctors will...

  17. Planting Performance and Super High Yield Cultivation Techniques of Yongyou 2640 with Bowl Seedling and Mechanical Transplanting%甬优2640种植表现及钵育机插超高产栽培技术

    Institute of Scientific and Technical Information of China (English)

    於永杰; 李华; 夏龙珠; 钱宗华

    2014-01-01

    引种示范和钵育机插超高产攻关试验表明,甬优2640具有熟期早、熟相好、穗型大、株型好、高温条件下结实率稳定等生育特性。本文研究并总结了甬优2640钵育机插超高产栽培技术要点:培育壮秧、精确机插、精确定量施肥、定量水浆调控、加强病虫防治,以期为甬优2640的推广应用及钵育机插超高产栽培提供借鉴。%Introduction and demonstration showed that Yongyou 2640 has the performance of early maturity, good color, big panicle, good plant type and stability in seed setting rate. The paper summarized the super high yield cultivation techniques of Yongyou 2640 with bowl seedling and mechanical transplanting, such as cultivating strong seedlings, precise mechannical transplanting, precise quantitative fertilization, water regulation and strengthening pest control.

  18. Super Special Codes using Super Matrices

    CERN Document Server

    Kandasamy, W B Vasantha; Ilanthenral, K

    2010-01-01

    The new classes of super special codes are constructed in this book using the specially constructed super special vector spaces. These codes mainly use the super matrices. These codes can be realized as a special type of concatenated codes. This book has four chapters. In chapter one basic properties of codes and super matrices are given. A new type of super special vector space is constructed in chapter two of this book. Three new classes of super special codes namely, super special row code, super special column code and super special codes are introduced in chapter three. Applications of these codes are given in the final chapter.

  19. Organisational structure of liver transplantation in the UK.

    Science.gov (United States)

    Neuberger, James

    2015-07-01

    This review aims to outline the delivery of liver transplant services in the UK. Liver transplantation in the UK is based on seven designated transplant units serving a population of just over 60 million people. Nearly 900 liver transplants were done in 2013/2014. Potential deceased donors are identified and referred to centrally employed specialist nurses for obtaining family consent and for donor characterisation. Organs are retrieved by a National Organ Retrieval Service, based on seven abdominal and six cardiothoracic retrieval teams providing a 24/7 service which has shown to be capable of retrieving organs from up to ten donors a day. Donated organs are allocated first nationally to those who qualify for super-urgent listing. The next priority is for splitting livers, and if there is no suitable recipient or the liver is not suitable for splitting, then livers are offered first to the local centre; each centre has a designated donor zone, adjusted annually to ensure equity between the number of patients listed and the number of donors. The allocation scheme is being reviewed, and national schemes based on need, utility and benefit are being assessed. Outcomes are monitored by National Health Service Blood and Transplant (NHSBT), and if there is a possibility of adverse deviation, then further inquiries are made. Outcomes, both from listing and from transplantation, are published by the centre on the NHSBT website ( www.odt.nhs.uk ). NHSBT works closely with stakeholders primarily through the advisory groups with clinicians, patients, lay members and professional societies and aims to provide openness and transparency. The system for organ donation and delivery of liver transplant in the UK has developed and is now providing an effective and efficient service, but there remains room for improvement.

  20. Urgent Care: the evolution of a revolution.

    Science.gov (United States)

    Resnick, Lee A

    2013-10-23

    The rapid and global growth of urgent care centers has had a revolutionary, though poorly understood, impact on the health care delivery system. The consumer-driven care model inherent in urgent care and other so-called convenience care models is permeating into more conventional health care models. In addition, physician and hospital payment models are evolving, especially in the United States and are creating new market forces that will impact the organization and importance of integrated health care networks in the future. Together, these transformative changes are creating evolutionary pressures on traditional urgent care. Lessons learned from both the Israeli and American experience can be especially helpful for drafting a successful urgent care model for the future. This is a commentary on http://www.ijhpr.org/content/2/1/38/.

  1. Super Factories

    Indian Academy of Sciences (India)

    D G Hitlin

    2006-11-01

    Heavy-flavor physics, in particular and physics results from the factories, currently provides strong constraints on models of physics beyond the Standard Model. A new generation of colliders, Super Factories, with 50 to 100 times the luminosity of existing colliders, can, in a dialog with LHC and ILC, provide unique clarification of new physics phenomena seen at those machines.

  2. Heart transplantation from older donors

    Directory of Open Access Journals (Sweden)

    V. N. Poptsov

    2017-01-01

    Full Text Available In the current situation of the shortage of suitable donor organs, heart transplantation from older donors is one of the ways to increase the performance of more heart transplants, particularly, in patients with urgent need of transplantation. While planning a heart transplantation from older donor one should consider increased risk of early cardiac allograft dysfunction, preexisting coronary artery disease, accelerated transplant vasculopathy which may adversely affect early and long-term survival of recipients. Subject to careful selection of donor–recipient pairs, effective prevention and treatment of early cardiac allograft dysfunction, pre-existing atherosclerosis and transplant vasculopathy the early and long-term survival of heart transplant recipients from older donors is comparable to heart transplantation from young donors.

  3. The Super Patalan Numbers

    OpenAIRE

    Richardson, Thomas M.

    2014-01-01

    We introduce the super Patalan numbers, a generalization of the super Catalan numbers in the sense of Gessel, and prove a number of properties analagous to those of the super Catalan numbers. The super Patalan numbers generalize the super Catalan numbers similarly to how the Patalan numbers generalize the Catalan numbers.

  4. Urgent discectomy: Clinical features and neurological outcome

    Directory of Open Access Journals (Sweden)

    Ruth Albert

    2016-01-01

    Conclusion: Motor deficits, sensory deficits, and cauda equina dysfunction were significantly improved immediately after urgent surgery. After 6 weeks, motor and sensory deficits were also significantly improved compared to the neurological status at discharge. Thus, we advocate immediate surgery of disc herniation in patients with acute onset of motor deficits, perineal numbness, or bladder or bowel dysfunction indicative of cauda equina syndrome.

  5. Urgent peritoneal dialysis or hemodialysis catheter dialysis.

    Science.gov (United States)

    Lok, Charmaine E

    2016-03-01

    Worldwide, there is a steady incident rate of patients with end-stage kidney disease (ESKD) who require renal replacement therapy. Of these patients, approximately one-third have an "unplanned" or "urgent" start to dialysis. This can be a very challenging situation where patients have either not had adequate time for education and decision making regarding dialysis modality and appropriate dialysis access, or a decision was made and plans were altered due to unforeseen circumstances. Despite such unplanned starts, clinicians must still consider the patient's ESKD "life-plan", which includes the best initial dialysis modality and access to suit the patient's individual goals and their medical, social, logistic, and facility circumstances. This paper will discuss the considerations of peritoneal dialysis and a peritoneal dialysis catheter access and hemodialysis and central venous catheter access in patients who require an urgent start to dialysis.

  6. Liver transplant

    Science.gov (United States)

    Hepatic transplant; Transplant - liver; Orthotopic liver transplant; Liver failure - liver transplant; Cirrhosis - liver transplant ... The donated liver may be from: A donor who has recently died and has not had liver injury. This type of ...

  7. Perceived quality in urgent transport sector

    Directory of Open Access Journals (Sweden)

    JOSE ANTONIO MARTÍNEZ GARCÍA

    2009-06-01

    Full Text Available This research has focused on the customer evaluation of perceived quality in the urgent transport service in Spain. Using different statistical procedures, such as ordinal regression, between-groups comparison or multilevel modeling, this study shows how the perceived service quality of the public company «Correos» is lower than several of the main competitors: Seur, MRW and Nacex. Despite the investment achieved by this public institution in order to improve service quality, these efforts have not been reflected in the customer evaluation, at least to the same extent as competitors. Several recommendations for further research are discussed in the final part of the study.

  8. Bone marrow transplant

    Science.gov (United States)

    Transplant - bone marrow; Stem cell transplant; Hematopoietic stem cell transplant; Reduced intensity nonmyeloablative transplant; Mini transplant; Allogenic bone marrow transplant; Autologous bone marrow transplant; Umbilical ...

  9. Quantitative comparisons of urgent care service providers.

    Science.gov (United States)

    Qin, Hong; Prybutok, Gayle L; Prybutok, Victor R; Wang, Bin

    2015-01-01

    The purpose of this paper is to develop, validate, and use a survey instrument to measure and compare the perceived quality of three types of US urgent care (UC) service providers: hospital emergency rooms, urgent care centres (UCC), and primary care physician offices. This study develops, validates, and uses a survey instrument to measure/compare differences in perceived service quality among three types of UC service providers. Six dimensions measured the components of service quality: tangibles, professionalism, interaction, accessibility, efficiency, and technical quality. Primary care physicians' offices scored higher for service quality and perceived value, followed by UCC. Hospital emergency rooms scored lower in both quality and perceived value. No significant difference was identified between UCC and primary care physicians across all the perspectives, except for interactions. The homogenous nature of the sample population (college students), and the fact that the respondents were recruited from a single university limits the generalizability of the findings. The patient's choice of a health care provider influences not only the continuity of the care that he or she receives, but compliance with a medical regime, and the evolution of the health care landscape. This work contributes to the understanding of how to provide cost effective and efficient UC services. This study developed and validated a survey instrument to measure/compare six dimensions of service quality for three types of UC service providers. The authors provide valuable data for UC service providers seeking to improve patient perceptions of service quality.

  10. 42 CFR 405.440 - Emergency and urgent care services.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Emergency and urgent care services. 405.440 Section... Emergency and urgent care services. (a) A physician or practitioner who has opted-out of Medicare under this subpart need not enter into a private contract to furnish emergency care services or urgent care...

  11. IN URGENT NEED OF A DOCTOR

    CERN Multimedia

    Medical Service

    2001-01-01

    IN URGENT NEED OF A DOCTOR GENEVA EMERGENCY SERVICES GENEVA AND VAUD 144 FIRE BRIGADE 118 POLICE 117 CERN FIREMEN 767-44-44 ANTI-POISONS CENTRE Open 24h/24h 01-251-51-51 Patient not fit to be moved, call family doctor, or: GP AT HOME, open 24h/24h 748-49-50 Association Of Geneva Doctors Emergency Doctors at home 07h-23h 322 20 20 Patient fit to be moved: HOPITAL CANTONAL CENTRAL 24 Micheli-du-Crest 372-33-11 ou 382-33-11 EMERGENCIES 382-33-11 ou 372-33-11 CHILDREN'S HOSPITAL 6 rue Willy-Donzé 372-33-11 MATERNITY 32 bvd.de la Cluse 382-68-16 ou 382-33-11 OPHTHALMOLOGY 22 Alcide Jentzer 382-33-11 ou 372-33-11 MEDICAL CENTRE CORNAVIN 1-3 rue du Jura 345 45 50 HOPITAL DE LA TOUR Meyrin EMERGENCIES 719-61-11 URGENCES PEDIATRIQUES 719-61-00 LA TOUR MEDICAL CENTRE 719-74-00 European Emergency Call 112 FRANCE EMERGENCY SERVICES 15 FIRE BRIGADE 18 POLICE 17 CERN FIREMEN AT HOME 00-41-22-767-44-44 ANTI-POISONS CENTRE Open 24h/24h 04-72-11-69-11 All doctors ...

  12. Magnesium deficiency in plants: An urgent problem

    Directory of Open Access Journals (Sweden)

    Wanli Guo

    2016-04-01

    Full Text Available Although magnesium (Mg is one of the most important nutrients, involved in many enzyme activities and the structural stabilization of tissues, its importance as a macronutrient ion has been overlooked in recent decades by botanists and agriculturists, who did not regard Mg deficiency (MGD in plants as a severe health problem. However, recent studies have shown, surprisingly, that Mg contents in historical cereal seeds have markedly declined over time, and two thirds of people surveyed in developed countries received less than their minimum daily Mg requirement. Thus, the mechanisms of response to MGD and ways to increase Mg contents in plants are two urgent practical problems. In this review, we discuss several aspects of MGD in plants, including phenotypic and physiological changes, cell Mg2 + homeostasis control by Mg2 + transporters, MGD signaling, interactions between Mg2 + and other ions, and roles of Mg2 + in plant secondary metabolism. Our aim is to improve understanding of the influence of MGD on plant growth and development and to advance crop breeding for Mg enrichment.

  13. Cornea Transplant

    Science.gov (United States)

    ... died from an unknown cause. During your cornea transplant On the day of your cornea transplant, you' ... when you see your eye doctor. Procedures to transplant a portion of the cornea With some types ...

  14. Transplant rejection

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000815.htm Transplant rejection To use the sharing features on this page, please enable JavaScript. Transplant rejection is a process in which a transplant ...

  15. Lung transplant

    Science.gov (United States)

    Solid organ transplant - lung ... the chance that the body will reject the transplant . Lungs can also be given by living donors. ... the person who is receiving it. During lung transplant surgery, you are asleep and pain-free (under ...

  16. T cell depleted haploidentical transplantation: positive selection

    Directory of Open Access Journals (Sweden)

    Franco Aversa

    2011-06-01

    Full Text Available Interest in mismatched transplantation arises from the fact that a suitable one-haplotype mismatched donor is immediately available for virtually all patients, particularly for those who urgently need an allogenic transplant. Work on one haplotype-mismatched transplants has been proceeding for over 20 years all over the world and novel transplant techniques have been developed. Some centres have focused on the conditioning regimens and post transplant immune suppression; others have concentrated on manipulating the graft which may be a megadose of extensively T celldepleted or unmanipulated progenitor cells. Excellent engraftment rates are associated with a very low incidence of acute and chronic GVHD and regimen-related mortality even in patients who are over 50 years old. Overall, event-free survival and transplant-related mortality compare favourably with reports on transplants from sources of stem cells other than the matched sibling.

  17. Economic evaluation of urgent-start peritoneal dialysis versus urgent-start hemodialysis in the United States.

    Science.gov (United States)

    Liu, Frank Xiaoqing; Ghaffari, Arshia; Dhatt, Harman; Kumar, Vijay; Balsera, Cristina; Wallace, Eric; Khairullah, Quresh; Lesher, Beth; Gao, Xin; Henderson, Heather; LaFleur, Paula; Delgado, Edna M; Alvarez, Melissa M; Hartley, Janett; McClernon, Marilyn; Walton, Surrey; Guest, Steven

    2014-12-01

    Patients presenting late in the course of kidney disease who require urgent initiation of dialysis have traditionally received temporary vascular catheters followed by hemodialysis. Recent changes in Medicare payment policy for dialysis in the USA incentivized the use of peritoneal dialysis (PD). Consequently, the use of more expeditious PD for late-presenting patients (urgent-start PD) has received new attention. Urgent-start PD has been shown to be safe and effective, and offers a mechanism for increasing PD utilization. However, there has been no assessment of the dialysis-related costs over the first 90 days of care. The objective of this study was to characterize the costs associated with urgent-start PD, urgent-start hemodialysis (HD), or a dual approach (urgent-start HD followed by urgent-start PD) over the first 90 days of treatment from a provider perspective. A survey of practitioners from 5 clinics known to use urgent-start PD was conducted to provide inputs for a cost model representing typical patients. Model inputs were obtained from the survey, literature review, and available cost data. Sensitivity analyses were also conducted. The estimated per patient cost over the first 90 days for urgent-start PD was $16,398. Dialysis access represented 15% of total costs, dialysis services 48%, and initial hospitalization 37%. For urgent-start HD, total per patient costs were $19,352, and dialysis access accounted for 27%, dialysis services 42%, and initial hospitalization 31%. The estimated cost for dual patients was $19,400. Urgent-start PD may offer a cost saving approach for the initiation of dialysis in eligible patients requiring an urgent-start to dialysis.

  18. Calculus super review

    CERN Document Server

    2012-01-01

    Get all you need to know with Super Reviews! Each Super Review is packed with in-depth, student-friendly topic reviews that fully explain everything about the subject. The Calculus I Super Review includes a review of functions, limits, basic derivatives, the definite integral, combinations, and permutations. Take the Super Review quizzes to see how much you've learned - and where you need more study. Makes an excellent study aid and textbook companion. Great for self-study!DETAILS- From cover to cover, each in-depth topic review is easy-to-follow and easy-to-grasp - Perfect when preparing for

  19. Algebra & trigonometry super review

    CERN Document Server

    2012-01-01

    Get all you need to know with Super Reviews! Each Super Review is packed with in-depth, student-friendly topic reviews that fully explain everything about the subject. The Algebra and Trigonometry Super Review includes sets and set operations, number systems and fundamental algebraic laws and operations, exponents and radicals, polynomials and rational expressions, equations, linear equations and systems of linear equations, inequalities, relations and functions, quadratic equations, equations of higher order, ratios, proportions, and variations. Take the Super Review quizzes to see how much y

  20. Effects of Interaction between Nitrogen Fertilizer and Planting Density on Leaf Type,Photosynthetic Characteristics and Yield of Mechanical-transplanting Super Hybrid Rice%氮肥和密度互作对机插超级杂交稻叶型、光合特性及产量的影响

    Institute of Scientific and Technical Information of China (English)

    陈乾; 刘科; 何爱斌; 龙继锐; 卢碧林; 田小海; 张运波

    2015-01-01

    The effects of different nitrogen fertilizer application amount and transplanting density on the leaf type,photosynthetic characteristic and yield of mechanical-transplanting super rice were studied with Quanliangyou 681 as material. The results showed that the interaction between the planting density and ni-trogen fertilizer significantly influenced the rate of effective leaf area,net photosynthetic rate and stomatal conductance,and did not significantly influenced the intercellular CO2 concentration. The lower planting density and nitrogen fertilizer application amount were beneficial for the increase of effective leaf area rate,lower planting density and higher fertilizer application amount were beneficial for the increase of net photosynthetic rate and stomatal conductance. The interaction between the planting density and nitrogen fertilizer significantly influenced the yield of super hybrid rice,the yield increased with the increase of the planting density and nitrogen fertilizer application amount,the treatment with high fertilizer application amount(250 kg / ha)and high density(2. 38 × 105 plants/ ha) obtained the highest yiled of 9. 26 t/ ha, which significantly higher than the other treatments. The interaction between the planting density and ni-trogen fertilizer mainly influenced the panicles number per plant and setting percentage,and panicles number per plant was crucial for high yield of mechanical-transplanting super hybrid rice,the proper in-crease of transplanting density was the approach to receive high yield under the suitable nitrogen fertilizer application amount in Jianghan Plain.%以超级杂交稻全两优681为材料,探讨不同氮肥用量和密度对江汉平原地区机插超级杂交稻叶型、光合特性及产量的影响。结果表明,氮肥和密度互作对高效叶面积率、净光合速率和气孔导度影响显著,对胞间 CO2浓度影响不显著。低氮、低密度有利于高效叶面积率的提高,高氮、低密度

  1. Super Tomboy Style

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Sparked by Super Girl, the androgynous look is in among Chinese youth On September 8, this year's top six contestants on the Super Girl television show, a singing contest for young women, stepped into the spotlight. Nearly none of them had long black hair or wore evening gowns, traditionally associated with beauty in China. Rather, they

  2. Pancreatic transplantation

    Directory of Open Access Journals (Sweden)

    Åke Andrén-Sandberg

    2010-01-01

    Full Text Available A pancreas transplant is a surgical procedure to place a healthy pancreas from a donor into a patient whose pancreas no longer functions properly. Exocrine pancreas transplantation remains the standard treatment of choice for patients with diabetes mellitus complicated by end-stage renal disease. The use of pancreas transplantation for type 2 diabetes mellitus is an emerging concept. A pancreas transplant is often done in conjunction with a kidney transplant. Even if pancreas transplantation provides the best glycemic control option for diabetes mellitus, it is associated with significant morbidities related to infectious disease. The present article provides with a review of pancreatic transplantation.

  3. Planning and scheduling of semi-urgent surgeries.

    Science.gov (United States)

    Zonderland, Maartje E; Boucherie, Richard J; Litvak, Nelly; Vleggeert-Lankamp, Carmen L A M

    2010-09-01

    This paper investigates the trade-off between cancellations of elective surgeries due to semi-urgent surgeries, and unused operating room (OR) time due to excessive reservation of OR time for semi-urgent surgeries. Semi-urgent surgeries, to be performed soon but not necessarily today, pose an uncertain demand on available hospital resources, and interfere with the planning of elective patients. For a highly utilized OR, reservation of OR time for semi-urgent surgeries avoids excessive cancellations of elective surgeries, but may also result in unused OR time, since arrivals of semi-urgent patients are unpredictable. First, using a queuing theory framework, we evaluate the OR capacity needed to accommodate every incoming semi-urgent surgery. Second, we introduce another queuing model that enables a trade-off between the cancelation rate of elective surgeries and unused OR time. Third, based on Markov decision theory, we develop a decision support tool that assists the scheduling process of elective and semi-urgent surgeries. We demonstrate our results with actual data obtained from a department of neurosurgery.

  4. Liver transplantation in the Nordic countries - An intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982-2013

    DEFF Research Database (Denmark)

    Fosby, Bjarte; Melum, Espen; Bjøro, Kristian

    2015-01-01

    AIM AND BACKGROUND: The Nordic Liver Transplant Registry (NLTR) accounts for all liver transplants performed in the Nordic countries since the start of the transplant program in 1982. Due to short waiting times, donor liver allocation has been made without considerations of the model of end......, acute hepatic failure, alcoholic liver disease, primary biliary cirrhosis and hepatocellular carcinoma are the five most frequent diagnoses (accounting for 15.3%, 10.8%, 10.6%, 9.3% and 9.0% of all transplants, respectively). Median waiting time for non-urgent liver transplantation during the last 10...

  5. Quantitative comparison of measurements of urgent care service quality.

    Science.gov (United States)

    Qin, Hong; Prybutok, Victor; Prybutok, Gayle

    2016-01-01

    Service quality and patient satisfaction are essential to health care organization success. Parasuraman, Zeithaml, and Berry introduced SERVQUAL, a prominent service quality measure not yet applied to urgent care. We develop an instrument to measure perceived service quality and identify the determinants of patient satisfaction/ behavioral intentions. We examine the relationships among perceived service quality, patient satisfaction and behavioral intentions, and demonstrate that urgent care service quality is not equivalent using measures of perceptions only, differences of expectations minus perceptions, ratio of perceptions to expectations, and the log of the ratio. Perceptions provide the best measure of urgent care service quality.

  6. Nonlinear Super Integrable Couplings of Super Classical-Boussinesq Hierarchy

    Directory of Open Access Journals (Sweden)

    Xiuzhi Xing

    2014-01-01

    Full Text Available Nonlinear integrable couplings of super classical-Boussinesq hierarchy based upon an enlarged matrix Lie super algebra were constructed. Then, its super Hamiltonian structures were established by using super trace identity. As its reduction, nonlinear integrable couplings of the classical integrable hierarchy were obtained.

  7. Small intestinal transplantation.

    LENUS (Irish Health Repository)

    Quigley, E M

    2012-02-03

    The past few years have witnessed a considerable shift in the clinical status of intestinal transplantation. A great deal of experience has been gained at the most active centers, and results comparable with those reported at a similar stage in the development of other solid-organ graft programs are now being achieved by these highly proficient transplant teams. Rejection and its inevitable associate, sepsis, remain ubiquitous, and new immunosuppressant regimes are urgently needed; some may already be on the near horizon. The recent success of isolated intestinal grafts, together with the mortality and morbidity attendant upon the development of advanced liver disease related to total parenteral nutrition, has prompted the bold proposal that patients at risk for this complication should be identified and should receive isolated small bowel grafts before the onset of end-stage hepatic failure. The very fact that such a suggestion has begun to emerge reflects real progress in this challenging field.

  8. Super-resolution

    DEFF Research Database (Denmark)

    Nasrollahi, Kamal; Moeslund, Thomas B.

    2014-01-01

    Super-resolution, the process of obtaining one or more high-resolution images from one or more low-resolution observations, has been a very attractive research topic over the last two decades. It has found practical applications in many real world problems in different fields, from satellite...... the contributions of different authors to the basic concepts of each group. Furthermore, common issues in super-resolution algorithms, such as imaging models and registration algorithms, optimization of the cost functions employed, dealing with color information, improvement factors, assessment of super...

  9. Urgent Care Transfers to an Academic Pediatric Emergency Department.

    Science.gov (United States)

    McCarthy, Jennifer L; Clingenpeel, Joel M; Perkins, Amy M; Eason, Margaret K

    2017-10-02

    The aim of this study was to investigate the hypothesis that a significant percentage of urgent care center to pediatric ED transfers can be discharged home without emergency department (ED) resource utilization. A retrospective chart review was completed for a 6-month period on all patients transferred from urgent care centers. A data collection tool focusing on demographics, diagnoses, reason for transfer, ED resource utilization, ED disposition, and 72-hour ED return was used. Each encounter was classified as "urgent" or "nonurgent" based on resource utilization criteria. Descriptive statistics were reported for demographics, encounter data, and 72-hour ED return stratified by nonurgent versus urgent classification. Two-sample t, χ, and Fisher exact tests were used to assess differences in characteristics between the nonurgent and urgent groups. One hundred nine patients met inclusion criteria. Of these, 93 (85%) were discharged from the ED. Twenty nine (27%) of the transferred patients were discharged without ED resource utilization. Seventy-two-hour return was noted for only 1 patient who was again discharged at the subsequent encounter. A large proportion of patients transferred from urgent care centers were directly discharged from the ED without any ED resource utilization. Eliminating or reducing such transfers has the potential to limit the amount of nonurgent ED visits, thus producing cost savings and better patient care.

  10. NETL Super Computer

    Data.gov (United States)

    Federal Laboratory Consortium — The NETL Super Computer was designed for performing engineering calculations that apply to fossil energy research. It is one of the world’s larger supercomputers,...

  11. Super-resolution

    DEFF Research Database (Denmark)

    Nasrollahi, Kamal; Moeslund, Thomas B.

    2014-01-01

    and aerial imaging to medical image processing, to facial image analysis, text image analysis, sign and number plates reading, and biometrics recognition, to name a few. This has resulted in many research papers, each developing a new super-resolution algorithm for a specific purpose. The current......Super-resolution, the process of obtaining one or more high-resolution images from one or more low-resolution observations, has been a very attractive research topic over the last two decades. It has found practical applications in many real world problems in different fields, from satellite...... the contributions of different authors to the basic concepts of each group. Furthermore, common issues in super-resolution algorithms, such as imaging models and registration algorithms, optimization of the cost functions employed, dealing with color information, improvement factors, assessment of super...

  12. Super-Kamiokande

    Science.gov (United States)

    Magro, Lluís Martí

    2016-06-01

    The Super-Kamiokande experiment performs a large variety of studies, many of them in the neutrino sector. The archetypes are atmospheric neutrino (recently awarded with the Nobel prize for Mr. T. Kajita) and the solar neutrinos analyses. In these proceedings we report our latest results and present updates to indirect dark matter searches, our solar neutrino analysis and discuss the future upgrade of Super-Kamiokande by loading gadolinium into our ultra-pure water.

  13. The Super Girl Effect

    Institute of Scientific and Technical Information of China (English)

    WANG PEI

    2006-01-01

    @@ In recent years, Changsha,the capital city of Hunan Province, has become famous across China for its innovative TV channel, in particular the cultural phenomenon of the Super Girl talent show. And as far as culture goes, Hunan TV is merely a reflection of a renaissance happening in the city. Animation, music halls, drama festivals and a famous book market are just some of the city's cultural sectors that are benefiting from the fame and notoriety of the Super Girl show.

  14. The formation of super-rings

    CERN Document Server

    Tenorio-Tagle, G

    1980-01-01

    The author has calculated the collision of a small neutral cloud (surface density approximately 10/sup 19/ cm/sup -2/) with a constant density galactic disk. Through the collision, a large amount of energy is deposited in a small volume of the galaxy, resulting in a supersonic expansion of very hot (10/sup 6/-10/sup 7/K) gas into the Galaxy and out of the galactic disk. The expansion generates a large cavity (a super-ring) with physical characteristics (diameter, velocity of expansion, etc.) in agreement with the observations, and a large volume of hot low-density gas with properties similar to those of the observed coronal gas. (31 refs).

  15. Nonlinear Super Integrable Couplings of Super Dirac Hierarchy and Its Super Hamiltonian Structures

    Institute of Scientific and Technical Information of China (English)

    尤福财

    2012-01-01

    We construct nonlinear super integrable couplings of the super integrable Dirac hierarchy based on an enlarged matrix Lie superalgebra. Then its super Hamiltonian structure is furnished by super trace identity. As its reduction, we gain the nonlinear integrable couplings of the classical integrable Dirac hierarchy.

  16. Hair transplant

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/007205.htm Hair transplant To use the sharing features on this page, please enable JavaScript. A hair transplant is a surgical procedure to improve baldness. Description ...

  17. Transplant services

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007457.htm Transplant services To use the sharing features on this ... are comfortable before, during, and after surgery. Information Transplant surgery is typically done to replace a diseased ...

  18. Long-term outcome of patients with and without super-response to CRT-D.

    Science.gov (United States)

    Franke, Jennifer; Keppler, Jeannette; Abadei, Alamara Karimi; Bajrovic, Amer; Meme, Lillian; Zugck, Christian; Raake, Philip W; Zitron, Edgar; Katus, Hugo A; Frankenstein, Lutz

    2016-04-01

    To compare outcome between patients with and without super-response to cardiac resynchronization therapy-defibrillator (CRT-D). In this cohort study, 167 consecutive CRT-D candidates were included. Super-response to CRT-D was defined clinically [improvement of ≥1 New York Heart Association (NYHA) class or ≥50 m in six-minute walk distance (6MWD)] and echocardiographically [increase of left ventricular ejection fraction (LVEF) ≥1 category (LVEF <30 to 30-40 % or 30-40 to 41-51 %) or reduction of left ventricular end-diastolic diameter (LVEDD) ≥10 mm]. Clinical outcome (death, cardiac transplantation and appropriate shock therapy) was compared between super-responders (n = 32) and non-super-responders (n = 135). During follow-up (616 patient-years; median 3.3 years), all-cause mortality was significantly lower in super-responders compared to non-super-responders (log rank p < 0.05). At least one appropriate shock was noted in 22 % of super-responders and 39 % of non-super-responders (p = 0.069). Time to appropriate shock therapy was significantly longer in super-responders (log rank p < 0.05). Event-free survival from death or cardiac transplantation was comparable between the two groups. Super-response to CRT-D is associated with improved survival and lower risk of appropriate shock therapy compared to non-super-responders. Further information about the mechanisms of super-response and its long-term consequences are needed to foresee favorable outcome after implantation of CRT-D.

  19. Access and care issues in urban urgent care clinic patients

    Directory of Open Access Journals (Sweden)

    Adams Jill C

    2009-12-01

    Full Text Available Abstract Background Although primary care should be the cornerstone of medical practice, inappropriate use of urgent care for non-urgent patients is a growing problem that has significant economic and healthcare consequences. The characteristics of patients who choose the urgent care setting, as well as the reasoning behind their decisions, is not well established. The purpose of this study was to determine the motivation behind, and characteristics of, adult patients who choose to access health care in our urgent care clinic. The relevance of understanding the motivation driving this patient population is especially pertinent given recent trends towards universal healthcare and the unclear impact it may have on the demands of urgent care. Methods We conducted a cross-sectional survey of patients seeking care at an urgent care clinic (UCC within a large acute care safety-net urban hospital over a six-week period. Survey data included demographics, social and economic information, reasons that patients chose a UCC, previous primary care exposure, reasons for delaying care, and preventive care needs. Results A total of 1, 006 patients were randomly surveyed. Twenty-five percent of patients identified Spanish as their preferred language. Fifty-four percent of patients reported choosing the UCC due to not having to make an appointment, 51.2% because it was convenient, 43.9% because of same day test results, 42.7% because of ability to get same-day medications and 15.1% because co-payment was not mandatory. Lack of a regular physician was reported by 67.9% of patients and 57.2% lacked a regular source of care. Patients reported delaying access to care for a variety of reasons. Conclusion Despite a common belief that patients seek care in the urgent care setting primarily for economic reasons, this study suggests that patients choose the urgent care setting based largely on convenience and more timely care. This information is especially applicable to

  20. Deforming super Riemann surfaces with gravitinos and super Schottky groups

    Energy Technology Data Exchange (ETDEWEB)

    Playle, Sam [Dipartimento di Fisica, Università di Torino and INFN, Sezione di Torino,Via P. Giuria 1, I-10125 Torino (Italy)

    2016-12-12

    The (super) Schottky uniformization of compact (super) Riemann surfaces is briefly reviewed. Deformations of super Riemann surface by gravitinos and Beltrami parameters are recast in terms of super Schottky group cohomology. It is checked that the super Schottky group formula for the period matrix of a non-split surface matches its expression in terms of a gravitino and Beltrami parameter on a split surface. The relationship between (super) Schottky groups and the construction of surfaces by gluing pairs of punctures is discussed in an appendix.

  1. VASCULAR COMPLICATIONS AFTER KIDNEY TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    M. Sh. Khubutia

    2013-01-01

    Full Text Available Aim: evaluation of the incidence and the pattern of vessel complications, efficacy of the prophylactic anticoagulation therapy after kidney transplantation. Materials and methods. From March 2007 till January 2013 421 patients: 230 men (54,6% and 191 women (45,4%; mean age 43,07 ± 11,62 undergone 429 kidney transplantations in the department of pancreas and kidney transplantation of the Scientific-Research Institute of Emergency Care named after N.V. Sklifosovsky. In order to evaluate the condition and the function of the kidney transplant ultrasound investigation (daily andacquisition(weekly wereused. In cases of kidney dysfunction and assumption of vessel complications we used computerized tomography. Besides, we used daily analysis of biochemical and clinical parameters of blood and urine. Results. The most common vessel complication was the thrombosis of the microvasculature of the kidney transplant due to acute humoral and combined rejection resistant to antirejection therapy (n = 9; 2,1%; in 4 cases there was a breakage of the transplant due to the acute rejection and the urgent transplantatectomy in an effort to save the patient; thrombosis of the transplantat artery occurred in 1 case (0,23%; we observed 2 cases (0,46% of the artery stenosis and 2 cases (0,46% of venous thrombosis. Conclusion. Summary frequency of vessel complications in our clinic, including thrombosis due to rejection, was 3,49%. It fully corresponds with data obtained from the global medical community. The incidence of great vessel thrombosis was less than 1% which indicates the adequate prophylactic anticoagulation therapy. For the benefit of early diacrisis of complications Doppler sonography is needed. In case of assumption of vessel complications urgent acquisition, computerized tomography and/ or angiography are to be held. 

  2. Raspberry Pi super cluster

    CERN Document Server

    Dennis, Andrew K

    2013-01-01

    This book follows a step-by-step, tutorial-based approach which will teach you how to develop your own super cluster using Raspberry Pi computers quickly and efficiently.Raspberry Pi Super Cluster is an introductory guide for those interested in experimenting with parallel computing at home. Aimed at Raspberry Pi enthusiasts, this book is a primer for getting your first cluster up and running.Basic knowledge of C or Java would be helpful but no prior knowledge of parallel computing is necessary.

  3. SuperQuant

    DEFF Research Database (Denmark)

    Gorshkov, Vladimir; Verano-Braga, Thiago; Kjeldsen, Frank

    2015-01-01

    SuperQuant is a quantitative proteomics data processing approach that uses complementary fragment ions to identify multiple co-isolated peptides in tandem mass spectra allowing for their quantification. This approach can be applied to any shotgun proteomics data set acquired with high mass accura...... of the same proteins were close to the values typical for other precursor ion-based quantification methods. The raw data is deposited to ProteomeXchange (PXD001907). The developed node is available for testing at https://github.com/caetera/SuperQuantNode....

  4. Urgent water challenges are not sufficiently researched”

    NARCIS (Netherlands)

    Van der Zaag, P.; Gupta, J.; Darvis, L.P.

    2009-01-01

    In this opinion paper we submit that water experts conduct comparatively little research on the more urgent challenges facing the global community. Five specific biases are identified. First, research in the field of water and sanitation is heavily biased against sanitation. Second, research on food

  5. Risk factors for hypotension in urgently intubated burn patients.

    Science.gov (United States)

    Dennis, Christopher J; Chung, Kevin K; Holland, Seth R; Yoon, Brian S; Milligan, Daun J; Nitzschke, Stephanie L; Maani, Christopher V; Hansen, Jacob J; Aden, James K; Renz, Evan M

    2012-12-01

    When urgently intubating patient in the burn intensive care unit (BICU), various induction agents, including propofol, are utilized that may induce hemodynamic instability. A retrospective review was performed of consecutive critically ill burn patients who underwent urgent endotracheal intubation in BICU. Basic burn-related demographic data, indication for intubation, and induction agents utilized were recorded. The primary outcomes of interest were clinically significant hypotension requiring immediate fluid resuscitation, initiation or escalation of vasopressors immediately after intubation. Secondary outcomes included ventilator days, stay length, and in-hospital mortality. Between January 2003 and August 2010, we identified 279 urgent intubations in 204 patients. Of these, the criteria for presumed sepsis were met in 60% (n=168) of the intubations. After intubation, 117 patients (42%) experienced clinically significant hypotension. Propofol (51%) was the most commonly utilized induction agent followed by etomidate (23%), ketamine (15%), and midazolam (11%). On multiple logistic regression, %TBSA (OR 1.016, 95% CI 1.004-1.027, ppredictors of hypotension. None of the induction agents, including propofol, were significantly associated with hypotension in patients with or without presumed sepsis. In critically ill burn patients undergoing urgent endotracheal intubation, specific induction agents, including propofol, were not associated with clinically significant hypotension. Presumed sepsis and %TBSA were the most important risk factors. Published by Elsevier Ltd.

  6. Do Urgent Caesarean Sections Have a Circadian Rhythm?

    Science.gov (United States)

    Doğru, Serkan; Doğru, Hatice Yılmaz; Karaman, Tuğba; Şahin, Aynur; Tapar, Hakan; Karaman, Serkan; Arıcı, Semih; Özsoy, Asker Zeki; Çakmak, Bülent; İşgüder, Çiğdem Kunt; Delibaş, İlhan Bahri; Karakış, Alkan

    2016-01-01

    Objective The primary goal of the present study was to demonstrate the existence of a possible circadian variation in urgent operative deliveries. Methods All urgent caesarean sections between 1 January 2014 and 1 January 2015 with known exact onset times of operation were included in this retrospective study. Cases that were previously scheduled for elective caesarean section were excluded. Information regarding age, delivery date, onset time of operation and type of anaesthesia was collected from the database. Analyses were completed using the Statistical Package for Social Sciences (SPSS Inc., Chicago, IL, USA) version 20.0 software. The statistical significance for all analyses was set at p<0.05. Results A total of 285 urgent caesarean section deliveries were included in the study. There were 126 (44.2%) deliveries during the day shift and 159 (55.8%) during the night shift. 80 patients (28.1%) received general anaesthesia and 65 (22.8%) received spinal anaesthesia in the morning shift, whereas 54 patients (18.9%) received general anaesthesia and 86 (30.2%) received spinal anaesthesia during the night shift. Conclusion The present study suggested that urgent caesarean sections revealed a circadian rhythm during the day. PMID:27366574

  7. 施氮量和栽培密度对超高产早稻Y两优302产量及其构成因素的影响%Effects of transplanting density and nitrogen fertilizer rate on yield and its components in super-high-yielding early rice variety Y-liangyou 302

    Institute of Scientific and Technical Information of China (English)

    赵荣德

    2011-01-01

    [目的]筛选适宜的施氮量和栽培密度,为广西桂北生态条件下超级稻高产栽培提供理论依据.[方法]以超高产早稻Y两优302为材料,探讨2个施氮水平150 kg/ha(N1)、225 kg/ha(N2)和4个栽培密度24.4万蔸/ha(D1)、30.6万蔸/ha(D2)、36.8万蔸/ha(D3)、42.6万蔸/ha(D4)在生育期内对水稻产量的影响.[结果]Y两优302产量主要受有效穗数和每穗粒数的影响,穗长和千粒重对产量影响不明显.在施氮量为225 kg/ha,栽培密度为24.4万~30.6万蔸/ha时,有利于Y两优302增产.[结论]较高的施氮量和较低的栽培密度有利于Y两优302产量的进一步提高.%[Objective]The present experiment was conducted to find out appropriate rate of nitrogen application and planting density for high-yield super rice variety Y-liangyou 302 in north region of Guangxi. [Method]A field experiment was conducted with different transplanting densities (24.4,30.6,36.8 and 42.6x104 hills/ha) and nitrogen fertilizer rates (150 and 225 kg/ha) to investigate their effect on the yield of super-high-yielding early indica rice variety Y-liangyou 302, during different growth stages. [Results]The yield of Y-liangyou 302 was mainly affected by panicles and spikelets per panicle, while the spike length and 1000-grain weight did not showed any significant influence on yield. The highest yield was recorded in the treatment with 225 kg/ha nitrogen fertilizer and 24.4x104 to 30.6x104 hils/ha planting density. [Conclusion]High nitrogen and low planting density is conducive to increase the yield of rice variety Y-liangyou 302 in north region of Guangxi.

  8. "Super Roman Pots"

    CERN Multimedia

    CERN PhotoLab

    1975-01-01

    Remotely controlled re-entrant vacuum vessels, with very thin (0.17 mm) central windows, that will be installed in each downstream arm of intersection I-8. Detectors for a coming physics experiment, placed inside these "Super Roman Pots", can be moved very close to the circulating ISR beams.

  9. A Super Roman Pot

    CERN Multimedia

    1975-01-01

    Remotely controlled re-entrant vacuum vessels, with very thin (0.17 mm) central windows, that were installed in each downstream arm of the ISR intersection I-8. Detectors placed inside these Super Roman Pots could be moved very close to the circulating ISR beams. (See Annual Report 1974 p. 110.)

  10. Transient ischemic attacks - Definition, risk prediction and urgent management

    Directory of Open Access Journals (Sweden)

    Sylaja P

    2009-01-01

    Full Text Available Recent evidence suggests that the risk of stroke in first few months after transient ischemic attack is higher than that was previously realized. There are clinical and imaging predictors which help in risk stratifying the patients to identify the high risk group who need immediate hospitalization and urgent evaluation. Recent advances in neuroimaging have revolutionized the evaluation of these patients. Further research is required in the deciding on the optimal treatment of these patients in the acute phase.

  11. Cities and Climate Change : Responding to an Urgent Agenda

    OpenAIRE

    Hoornweg, Daniel; Freire, Mila; Marcus J. Lee; Bhada-Tata, Perinaz; Yuen, Belinda

    2011-01-01

    The 5th urban research symposium on cities and climate change responding to an urgent agenda, held in Marseille in June 2009, sought to highlight how climate change and urbanization are converging to create one of the greatest challenges of our time. Cities consume much of the world's energy, and thus produce much of the world's greenhouse gas emissions. Yet cities, to varying extents, are...

  12. Corneal Transplantation

    DEFF Research Database (Denmark)

    Hjortdal, Jesper Østergaard

    Corneal transplantation has been performed for more than 100 years. Until 15 years ago the state-of-the art type of transplantation was penetrating keratoplasty, but since the start of this millennium, newly designed surgical techniques have developed considerably. Today, the vast majority of ker...

  13. Regulating Transplants

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Legislation to determine brain death is viewed as essential in controlling the organ transplant industry Organ transplant represents a very sensitive and complicated issue. Experts say the temporary administrative regulations recently promulgated by the Central Government are an important step, but relevant laws and regulations must follow. Among these, the

  14. Islet Transplantation

    Science.gov (United States)

    ... transplanted islet cells failed. But in recent years, scientists have begun to make rapid advances in transplant technology, and some of the most exciting new research comes to us from researchers at the University of ... Canada. These scientists have used a new procedure called the Edmonton ...

  15. SuperSegger

    DEFF Research Database (Denmark)

    Stylianidou, Stella; Brennan, Connor; Nissen, Silas B

    2016-01-01

    -colonies with many cells, facilitating the analysis of cell-cycle dynamics in bacteria as well as cell-contact mediated phenomena. This package has a range of built-in capabilities for characterizing bacterial cells, including the identification of cell division events, mother, daughter, and neighboring cells......Many quantitative cell biology questions require fast yet reliable automated image segmentation to identify and link cells from frame-to-frame, and characterize the cell morphology and fluorescence. We present SuperSegger, an automated MATLAB-based image processing package well......-suited to quantitative analysis of high-throughput live-cell fluorescence microscopy of bacterial cells. SuperSegger incorporates machine-learning algorithms to optimize cellular boundaries and automated error resolution to reliably link cells from frame-to-frame. Unlike existing packages, it can reliably segment micro...

  16. NASA Super Pressure Balloon

    Science.gov (United States)

    Fairbrother, Debbie

    2017-01-01

    NASA is in the process of qualifying the mid-size Super Pressure Balloon (SPB) to provide constant density altitude flight for science investigations at polar and mid-latitudes. The status of the development of the 18.8 million cubic foot SPB capable of carrying one-tone of science to 110,000 feet, will be given. In addition, the operating considerations such as launch sites, flight safety considerations, and recovery will be discussed.

  17. Super-diversité

    NARCIS (Netherlands)

    Crul, M.R.J.; Schneider, J.; Lelie, F.

    2013-01-01

    Le concept de super-diversité, en cernant les conditions d'un scénario 'avenir optimiste, offre un nouvel éclairage au débat sur l'intégration. Nous sommes à la croisée des chemins. Cette étude comparative internationale montre qu'un avenir souriant se profile dans les villes qui donnent des chances

  18. Performing the Super Instrument

    DEFF Research Database (Denmark)

    Kallionpaa, Maria

    2016-01-01

    The genre of contemporary classical music has seen significant innovation and research related to new super, hyper, and hybrid instruments, which opens up a vast palette of expressive potential. An increasing number of composers, performers, instrument designers, engineers, and computer programmers...... provides the performer extensive virtuoso capabilities in terms of instrumental range, harmony, timbre, or spatial, textural, acoustic, technical, or technological qualities. The discussion will be illustrated by a composition case study involving augmented musical instrument electromagnetic resonator...

  19. Performing the Super Instrument

    DEFF Research Database (Denmark)

    Kallionpaa, Maria

    2016-01-01

    provides the performer extensive virtuoso capabilities in terms of instrumental range, harmony, timbre, or spatial, textural, acoustic, technical, or technological qualities. The discussion will be illustrated by a composition case study involving augmented musical instrument electromagnetic resonator......The genre of contemporary classical music has seen significant innovation and research related to new super, hyper, and hybrid instruments, which opens up a vast palette of expressive potential. An increasing number of composers, performers, instrument designers, engineers, and computer programmers...

  20. Characterising Super-Earths

    Directory of Open Access Journals (Sweden)

    Valencia D.

    2011-02-01

    Full Text Available The era of Super-Earths has formally begun with the detection of transiting low-mass exoplanets CoRoT-7b and GJ 1214b. In the path of characterising super-Earths, the first step is to infer their composition. While the discovery data for CoRoT-7b, in combination with the high atmospheric mass loss rate inferred from the high insolation, suggested that it was a rocky planet, the new proposed mass values have widened the possibilities. The combined mass range 1−10 M⊕ allows for a volatile-rich (and requires it if the mass is less than 4 M⊕ , an Earth-like or a super-Mercury-like composition. In contrast, the radius of GJ 1214b is too large to admit a solid composition, thus it necessarily to have a substantial gas layer. Some evidence suggests that within this gas layer H/He is a small but non-negligible component. These two planets are the first of many transiting low-mass exoplanets expected to be detected and they exemplify the limitations faced when inferring composition, which come from the degenerate character of the problem and the large error bars in the data.

  1. Super Fuzzy Matrices and Super Fuzzy Models for Social Scientists

    CERN Document Server

    Kandasamy, W B Vasantha; Amal, K

    2008-01-01

    This book introduces the concept of fuzzy super matrices and operations on them. This book will be highly useful to social scientists who wish to work with multi-expert models. Super fuzzy models using Fuzzy Cognitive Maps, Fuzzy Relational Maps, Bidirectional Associative Memories and Fuzzy Associative Memories are defined here. The authors introduce 13 multi-expert models using the notion of fuzzy supermatrices. These models are described with illustrative examples. This book has three chapters. In the first chaper, the basic concepts about super matrices and fuzzy super matrices are recalled. Chapter two introduces the notion of fuzzy super matrices adn their properties. The final chapter introduces many super fuzzy multi expert models.

  2. Super-quantum curves from super-eigenvalue models

    CERN Document Server

    Ciosmak, Paweł; Manabe, Masahide; Sułkowski, Piotr

    2016-01-01

    In modern mathematical and theoretical physics various generalizations, in particular supersymmetric or quantum, of Riemann surfaces and complex algebraic curves play a prominent role. We show that such supersymmetric and quantum generalizations can be combined together, and construct supersymmetric quantum curves, or super-quantum curves for short. Our analysis is conducted in the formalism of super-eigenvalue models: we introduce $\\beta$-deformed version of those models, and derive differential equations for associated $\\alpha/\\beta$-deformed super-matrix integrals. We show that for a given model there exists an infinite number of such differential equations, which we identify as super-quantum curves, and which are in one-to-one correspondence with, and have the structure of, super-Virasoro singular vectors. We discuss potential applications of super-quantum curves and prospects of other generalizations.

  3. Super-quantum curves from super-eigenvalue models

    Science.gov (United States)

    Ciosmak, Paweł; Hadasz, Leszek; Manabe, Masahide; Sułkowski, Piotr

    2016-10-01

    In modern mathematical and theoretical physics various generalizations, in particular supersymmetric or quantum, of Riemann surfaces and complex algebraic curves play a prominent role. We show that such supersymmetric and quantum generalizations can be combined together, and construct supersymmetric quantum curves, or super-quantum curves for short. Our analysis is conducted in the formalism of super-eigenvalue models: we introduce β-deformed version of those models, and derive differential equations for associated α/ β-deformed super-matrix integrals. We show that for a given model there exists an infinite number of such differential equations, which we identify as super-quantum curves, and which are in one-to-one correspondence with, and have the structure of, super-Virasoro singular vectors. We discuss potential applications of super-quantum curves and prospects of other generalizations.

  4. Super-quantum curves from super-eigenvalue models

    Energy Technology Data Exchange (ETDEWEB)

    Ciosmak, Paweł [Faculty of Mathematics, Informatics and Mechanics, University of Warsaw,ul. Banacha 2, 02-097 Warsaw (Poland); Hadasz, Leszek [M. Smoluchowski Institute of Physics, Jagiellonian University,ul. Łojasiewicza 11, 30-348 Kraków (Poland); Manabe, Masahide [Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Sułkowski, Piotr [Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E. California Blvd, Pasadena, CA 91125 (United States)

    2016-10-10

    In modern mathematical and theoretical physics various generalizations, in particular supersymmetric or quantum, of Riemann surfaces and complex algebraic curves play a prominent role. We show that such supersymmetric and quantum generalizations can be combined together, and construct supersymmetric quantum curves, or super-quantum curves for short. Our analysis is conducted in the formalism of super-eigenvalue models: we introduce β-deformed version of those models, and derive differential equations for associated α/β-deformed super-matrix integrals. We show that for a given model there exists an infinite number of such differential equations, which we identify as super-quantum curves, and which are in one-to-one correspondence with, and have the structure of, super-Virasoro singular vectors. We discuss potential applications of super-quantum curves and prospects of other generalizations.

  5. Logistics and outcome in urgent and emergency colorectal surgery

    DEFF Research Database (Denmark)

    Elshove-Bolk, J.; Ellensen, V. S.; Baatrup, G.

    2010-01-01

    Aim: Infrastructure-related factors are seldom described in detail in studies on outcome after surgical procedures. We studied patient, procedure, physician and infrastructure characteristics and their effect on outcome at a Norwegian University hospital. Method: All patients admitted between 1st...... January 2002 and 30th June 2003 who underwent urgent or emergency colorectal surgery were extracted from the hospital databases and retrospectively analysed. Results: There were 196 patients. The overall complication rate was 39%. Forty-six (24%) patients died during admission after surgery. Those who...

  6. Path from Urgent Operational Need to Program of Record

    Science.gov (United States)

    2014-04-01

    Manage the realm of “what’s possible?”Manage the realm of “what’s available?” Raw prototypes Expeditionary Labs Products Mature Prototypes The Rapid...RDECOM • COCOM(s) • Operational Army • Gap analysis • MACOM(s) • TRADOC In use in a theater Operationally Mature Screen Candidate List Categorize and...required in accor- dance with 10 United States Code § 2366a and § 2366b. Affordability assessments are usually not applicable to urgent need solutions

  7. Role of urgent care staff in organ donation.

    Science.gov (United States)

    Garside, Marie; Garside, Jules

    2010-10-01

    A detailed review of donation activity since the introduction of an embedded specialist nurse in organ donation (SNOD) in Norfolk and Norwich University Hospitals NHS Foundation Trust has confirmed the benefits of this role for the identification and referral of potential donors by emergency department (ED) staff. This article argues that, as EDs across the U.K. introduce SNODs, more organs will become available for transplant.

  8. [Urgent laparoscopic adrenalectomy in acute crisis caused by pheochromocytoma].

    Science.gov (United States)

    Bereczky, Bíborka; Madách, Krisztina; Gál, János; István, Gábor; Sugár, István; Ondrejka, Pál; Vörös, Attila

    2014-06-01

    Authors present the case of a 30-year-old female patient, who was admitted to the ICU because of hypertensive crisis accompanied by chest complains, cardiac decompensation, progrediating short of breath and unconsciousness. Despite the quick examinations and the prompt treatment multi-organ failure developed 3 days after admission. Investigations revealed the underlying cause, which was a left-sided suprarenal neoplasm. Hence, multidisciplinary decision was made to carry out a laparoscopic adrenalectomy urgently. The histology examination of the removed neoplasm was pheochromocytoma. In the postoperative period the condition of the patient gradually improved, her symptoms and complains settled, and finally she was discharged in a healthy condition. The diagnosis of a pheochromocytoma is a difficult task, the symptoms and complains caused by it can simulate many other illnesses. The acute crisis caused by pheochromocytoma usually can be treated conservatively, but in more severe cases with impending multi-organ failure an urgent operative treatment can be unavoidable. Though the operative risk is relatively high, the correct intra- and postoperative treatment with a quick laparoscopic procedure can be effective.

  9. Extracorporeal membrane oxygenation after living-related liver transplant.

    Science.gov (United States)

    Gedik, Ender; Çelik, Muhammet Reha; Otan, Emrah; Dişli, Olcay Murat; Erdil, Nevzat; Bayındır, Yaşar; Kutlu, Ramazan; Yılmaz, Sezai

    2015-04-01

    Various types of extracorporeal membrane oxygenation methods have been used in liver transplant operations. The main indications are portopulmonary or hepatopulmonary syndromes and other cardiorespiratory failure syndromes that are refractory to conventional therapy. There is little literature available about extracorporeal membrane oxygenation, especially after liver transplant. We describe our experience with 2 patients who had living-related liver transplant. A 69-year-old woman had refractory aspergillosis pneumonia and underwent pumpless extracorporeal lung assist therapy 4 weeks after liver transplant. An 8-month-old boy with biliary atresia underwent urgent liver transplant; he received venoarterial extracorporeal membrane oxygenation therapy on postoperative day 1. Despite our unsuccessful experience with 2 patients, extracorporeal membrane oxygenation and pumpless extracorporeal lung assist therapy for liver transplant patients may improve prognosis in selected cases.

  10. Lung Transplant

    Science.gov (United States)

    ... will recover in the hospital’s intensive care unit (ICU) before moving to a hospital room for one to three weeks. Your doctor may recommend pulmonary rehabilitation after your lung transplant surgery to help you ...

  11. Liver Transplant

    Science.gov (United States)

    ... health, plan to pay for transplant related medical expenses, and emotional support family and friends will provide. ... hospital room when ready. The length of your hospitalization depends on your specific circumstances and if complications ...

  12. Acute cardiac tamponade: an unusual cause of acute renal failure in a renal transplant recipient.

    Science.gov (United States)

    Nampoory, Naryanan; Gheith, Osama; Al-Otaibi, Torki; Halim, Medhat; Nair, Prasad; Said, Tarek; Mosaad, Ahmed; Al-Sayed, Zakareya; Alsayed, Ayman; Yagan, Jude

    2015-04-01

    We report a case of slow graft function in a renal transplant recipient caused by uremic acute pericardial effusion with tamponade. Urgent pericardiocentesis was done with an improvement in blood pressure, immediate diuresis, and quick recovery of renal function back to baseline. Pericardial tamponade should be included in consideration of causes of type 1 cardiorenal syndrome in renal transplant recipients.

  13. Heart transplantation

    OpenAIRE

    Cheng, Allen; Slaughter, Mark S.

    2014-01-01

    Heart failure remains a major global problem with approximately 6 million individuals suffering from heart failure in the United States alone. The surgical technique of heart transplantation, popularized by Dr. Norman Shumway, has led to its success and currently remains the best treatment options for patients with end-stage. However, with the continued limitation of donor organs and the rapid development of ventricular assist device technology, the number of patients bridged to transplant wi...

  14. Super insulating aerogel glazing

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe; Jensen, Karsten Ingerslev; Kristiansen, Finn Harken

    2004-01-01

    Monolithic silica aerogel offers the possibility of combining super insulation and high solar energy transmittance, which has been the background for a previous and a current EU project on research and development of monolithic silica aerogel as transparent insulation in windows. Generally, windows...... form the weakest part of the thermal envelope with respect to heat loss coefficient, but on the other hand also play an important role for passive solar energy utilisation. For window orientations other than south, the net energy balance will be close to or below zero. However, the properties...

  15. Super insulating aerogel glazing

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe; Jensen, Karsten Ingerslev; Kristiansen, Finn Harken

    2005-01-01

    This paper describes the application results of a previous and current EU-project on super insulating glazing based on monolithic silica aerogel. Prototypes measuring approx. 55´55 cm2 have been made with 15 mm evacuated aerogel between two layers of low-iron glass. Anti-reflective treatment...... of the glass and a heat-treatment of the aerogel increases the visible quality and the solar energy transmittance. A low-conductive rim seal solution with the required vacuum barrier properties has been developed along with a reliable assembly and evacuation process. The prototypes have a centre heat loss...

  16. Super-heptazethrene

    KAUST Repository

    Zeng, Wangdong

    2016-05-30

    The challenging synthesis of a laterally extended heptazethrene molecule, the super-heptazethrene derivative SHZ-CF3, is reported. This molecule was prepared using a strategy involving a multiple selective intramolecular Friedel–Crafts alkylation followed by oxidative dehydrogenation. Compound SHZ-CF3 exhibits an open-shell singlet diradical ground state with a much larger diradical character compared with the heptazethrene derivatives. An intermediate dibenzo-terrylene SHZ-2H was also obtained during the synthesis. This study provides a new synthetic method to access large-size quinoidal polycyclic hydrocarbons with unique physical properties.

  17. SINGLE-CENTER EXPERIENCE OF ABO-INCOMPATIBLE LIVER TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    S. V. Gautier

    2011-01-01

    Full Text Available Since 2008 up to 2010 eight ABO-incompatible liver transplantations have been performed in our center: one of them was urgent liver transplantation to adult patient from deceased donor, other seven were transplantations of left lateral segment to children from living relative donors. Own experience, as well as world one, proves, that barrier of ABO-incompatibility can be overcome more successfully in liver transplantation, particularly in pediatric population, that in other solid organs transplantation. Good results can be achieved even with less ag- gressive immunosuppressive therapy. Recipient conditioning before operation can significantly improve results of ABO-incompatible liver transplantation, but as own experience has shown, often there’s no need to hold some special preparation of children, because their anti-ABO antibodies are very low or absent before transplantation and do not increase after it. Thereby ABO-incompatible liver transplantation is reasonable in urgent cases and in pediatric population because of the limited pull of living relative donors for children. 

  18. Stem Cell Transplant

    Science.gov (United States)

    ... transplant is a procedure that infuses healthy blood stem cells into your body to replace your damaged or ... A bone marrow transplant is also called a stem cell transplant. A bone marrow transplant may be necessary ...

  19. After the Transplant

    Science.gov (United States)

    ... Types Risk Factors Prevention & Early Detection After The Transplant After dealing with the effects of long-term ... Lifestyle changes Pregnancy after transplant Cancer after transplant Transplants By Organ - January 1, 1988 - April 30, 2016 ...

  20. Quantitative super-resolution microscopy

    NARCIS (Netherlands)

    Harkes, Rolf

    2016-01-01

    Super-Resolution Microscopy is an optical fluorescence technique. In this thesis we focus on single molecule super-resolution, where the position of single molecules is determined. Typically these molecules can be localized with a 10 to 30nm precision. This technique is applied in four different s

  1. HESS Opinions "Urgent water challenges are not sufficiently researched"

    Directory of Open Access Journals (Sweden)

    L. P. Darvis

    2009-03-01

    Full Text Available In this opinion paper we submit that water experts conduct comparatively little research on the more urgent challenges facing the global community. Apparently there is a mismatch between the global demand for knowledge and the finance for and supply of knowledge. This mismatch is identified here as a problem that we water scientists must try to confront and resolve. We need to understand why this mismatch occurs and persists, in order to find ways to break out of the impasse. Although this paper addresses a critical challenge it does not aim to be exhaustive or definitive. We merely identify the persistence of intransigent water problems as a research object in itself.

  2. Cryptococcosis in kidney transplant recipients in a Chinese university hospital and a review of published cases

    Directory of Open Access Journals (Sweden)

    Ya-li Yang

    2014-09-01

    Conclusions: Cryptococcosis is a serious infection among kidney transplant recipients in mainland China. It has unique characteristics, such as a relatively long time to onset after kidney transplantation, and diverse clinical manifestations. Treatment with intrathecal injection of amphotericin B is considered effective for central nervous system involvement. The findings of this study also highlight the urgent need for multicenter, prospective, and multidisciplinary clinical studies and education on cryptococcosis in kidney transplant recipients in China.

  3. Sclerosing encapsulating peritonitis in a liver transplant patient: A case report

    Institute of Scientific and Technical Information of China (English)

    Chien-Hua Lin; Jyh-Cherng Yu; Teng-Wei Chen; De-Chuan Chan; Cheng-Jueng Chen; Chung-Bao Hsieh

    2005-01-01

    We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation. Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during an initial PVS. However, intestinal obstruction developed 2 wk after liver transplantation; and a cocoon abdomen was found upon exploration. This is the first reported case of cocoon abdomen caused by PVS and exacerbated by liver transplantation.

  4. Super insulating aerogel glazing

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe; Jensen, Karsten Ingerslev; Kristiansen, Finn Harken

    2004-01-01

    Monolithic silica aerogel offers the possibility of combining super insulation and high solar energy transmittance, which has been the background for a previous and a current EU project on research and development of monolithic silica aerogel as transparent insulation in windows. Generally, windows...... form the weakest part of the thermal envelope with respect to heat loss coefficient, but on the other hand also play an important role for passive solar energy utilisation. For window orientations other than south, the net energy balance will be close to or below zero. However, the properties...... of aerogel glazing will allow for a positive net energy gain even for north facing vertical windows in a Danish climate during the heating season. This means that high quality daylight can be obtained even with additional energy gain. On behalf of the partners of the two EU projects, results related...

  5. Pancreas transplants

    Energy Technology Data Exchange (ETDEWEB)

    Chandra, J.; Phillips, R.R.; Boardman, P.; Gleeson, F.V. [Department of Radiology, Churchill Hospital, Headington, Oxford (United Kingdom); Anderson, E.M. [Department of Radiology, Churchill Hospital, Headington, Oxford (United Kingdom)], E-mail: ewan.anderson@orh.nhs.uk

    2009-07-15

    Cadaveric, whole pancreas transplantation has proved an effective therapy in the treatment of long-standing type 1 diabetes mellitus and is capable of achieving an insulin-independent eugyclaemic state. As a result, this procedure is being increasingly performed. However, the surgical procedure is complex and unfamiliar to many radiologists. Imaging with computed tomography (CT) and magnetic resonance imaging (MRI) gives excellent results and can be used confidently to diagnose vascular, enteric, and immune-mediated complications. We present a review of the normal post-transplantation appearance and the features of early and late complications.

  6. Cadaveric transplantation.

    Directory of Open Access Journals (Sweden)

    Gokal R

    1993-10-01

    Full Text Available Transplantation is already the optimum treatment for terminal renal failure. Donor organ shortage means that there are large number of patients on dialysis awaiting this treatment. This has in some countries led to unacceptable unscrupulous practices of live non-related graft donation. The outcome of graft and patient after transplantation has improved significantly based on a better understanding of immunopathology, immunosuppression and tissue typing. The future is promising and xenografting may well solve the organ shortage but undoubtedly will raise other issues.

  7. Kidney transplantation after liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Li-Yang Wu; Hang Liu; Wei Liu; Han Li; Xiao-Dong Zhang

    2016-01-01

    Kidney transplantation after liver transplanta-tion (KALT) offers longer survival and a better quality of life to liver transplantation recipients who develop chronic renal failure. This article aimed to discuss the efifcacy and safety of KALT compared with other treatments. The medical records of 5 patients who had undergone KALT were retrospectively studied, together with a literature review of studies. Three of them developed chronic renal failure after liver transplanta-tion because of calcineurin inhibitor (CNI)-induced neph-rotoxicity, while the others had lupus nephritis or non-CNI drug-induced nephrotoxicity. No mortality was observed in the 5 patients. Three KALT cases showed good prognoses, maintaining a normal serum creatinine level during entire follow-up period. Chronic rejection occurred in the other two patients, and a kidney graft was removed from one of them. Our data suggested that KALT is a good alternative to dialysis for liver transplantation recipients. The cases also indicate that KALT can be performed with good long-term survival.

  8. Biliary leakage after urgent cholecystectomy: Optimizationof endoscopic treatment

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    AIM To investigate the results of endoscopic treatmentof postoperative biliary leakage occurring after urgentcholecystectomy with a long-term follow-up.METHODS: This is an observational database studyconducted in a tertiary care center. All consecutivepatientswho underwent endoscopic retrograde cholangiography(ERC) for presumed postoperative biliaryleakage after urgent cholecystectomy in the periodbetween April 2008 and April 2013 were consideredfor this study. Patients with bile duct transection andbiliary strictures were excluded. Biliary leakage wassuspected in the case of bile appearance from eitherpercutaneous drainage of abdominal collection orabdominal drain placed at the time of cholecystectomy.Procedural and main clinical characteristics of allconsecutive patients with postoperative biliary leakageafter urgent cholecystectomy, such as indication forcholecystectomy, etiology and type of leakage, ERCfindings and post-ERC complications, were collectedfrom our electronic database. All patients in whomthe leakage was successfully treated endoscopicallywere followed-up after they were discharged from thehospital and the main clinical characteristics, laboratorydata and common bile duct diameter were electronicallyrecorded.RESULTS: During a five-year period, biliary leakagewas recognized in 2.2% of patients who underwenturgent cholecystectomy. The median time fromcholecystectomy to ERC was 6 d (interquartile range,4-11 d). Endoscopic interventions to manage biliaryleakage included biliary stent insertion with or withoutbiliary sphincterotomy. In 23 (77%) patients after firstendoscopic treatment bile flow through existing surgicaldrain ceased within 11 d following biliary therapeuticendoscopy (median, 4 d; interquartile range, 2-8 d).In those patients repeat ERC was not performed and the biliary stent was removed on gastroscopy. In seven(23%) patients repeat ERC was done within one tofourth week after their first ERC, depending on theextent

  9. Hematopoietic stem cell transplantation for infantile osteopetrosis.

    Science.gov (United States)

    Orchard, Paul J; Fasth, Anders L; Le Rademacher, Jennifer; He, Wensheng; Boelens, Jaap Jan; Horwitz, Edwin M; Al-Seraihy, Amal; Ayas, Mouhab; Bonfim, Carmem M; Boulad, Farid; Lund, Troy; Buchbinder, David K; Kapoor, Neena; O'Brien, Tracey A; Perez, Miguel A Diaz; Veys, Paul A; Eapen, Mary

    2015-07-01

    We report the international experience in outcomes after related and unrelated hematopoietic transplantation for infantile osteopetrosis in 193 patients. Thirty-four percent of transplants used grafts from HLA-matched siblings, 13% from HLA-mismatched relatives, 12% from HLA-matched, and 41% from HLA-mismatched unrelated donors. The median age at transplantation was 12 months. Busulfan and cyclophosphamide was the most common conditioning regimen. Long-term survival was higher after HLA-matched sibling compared to alternative donor transplantation. There were no differences in survival after HLA-mismatched related, HLA-matched unrelated, or mismatched unrelated donor transplantation. The 5- and 10-year probabilities of survival were 62% and 62% after HLA-matched sibling and 42% and 39% after alternative donor transplantation (P = .01 and P = .002, respectively). Graft failure was the most common cause of death, accounting for 50% of deaths after HLA-matched sibling and 43% of deaths after alternative donor transplantation. The day-28 incidence of neutrophil recovery was 66% after HLA-matched sibling and 61% after alternative donor transplantation (P = .49). The median age of surviving patients is 7 years. Of evaluable surviving patients, 70% are visually impaired; 10% have impaired hearing and gross motor delay. Nevertheless, 65% reported performance scores of 90 or 100, and in 17%, a score of 80 at last contact. Most survivors >5 years are attending mainstream or specialized schools. Rates of veno-occlusive disease and interstitial pneumonitis were high at 20%. Though allogeneic transplantation results in long-term survival with acceptable social function, strategies to lower graft failure and hepatic and pulmonary toxicity are urgently needed.

  10. Xinjiang Girl World Super Model

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Leading Chinese model Yue Mei won thetitle of World Super Model at the ’98 WorldSuper Model Competition held in FranceSeptember 6 - 17. Yue, a university studentfrom the Xinjiang Uygur AutonomousRegion, had won the top title at ’98 ChinaSuper Model Competition held in Beijingone month earier.After that, she underwentone month’s professional modeling trainingwith the New Silk Road ModelingManagement Company before setting off forthe world competition. In France, Yueimpressed the judges with her strikingfeatures, and display of oriental elegance and

  11. Magnesium deficiency in plants:An urgent problem

    Institute of Scientific and Technical Information of China (English)

    Wanli Guo; Hussain Nazim; Zongsuo Liang; Dongfeng Yang

    2016-01-01

    Although magnesium (Mg) is one of the most important nutrients, involved in many enzyme activities and the structural stabilization of tissues, its importance as a macronutrient ion has been overlooked in recent decades by botanists and agriculturists, who did not regard Mg deficiency (MGD) in plants as a severe health problem. However, recent studies have shown, surprisingly, that Mg contents in historical cereal seeds have markedly declined over time, and two thirds of people surveyed in developed countries received less than their minimum daily Mg requirement. Thus, the mechanisms of response to MGD and ways to increase Mg contents in plants are two urgent practical problems. In this review, we discuss several aspects of MGD in plants, including phenotypic and physiological changes, cell Mg2+homeostasis control by Mg2+transporters, MGD signaling, interactions between Mg2+and other ions, and roles of Mg2+in plant secondary metabolism. Our aim is to improve understanding of the influence of MGD on plant growth and development and to advance crop breeding for Mg enrichment.

  12. Magnesium deficiency in plants:An urgent problem

    Institute of Scientific and Technical Information of China (English)

    Wanli Guo; Hussain Nazim; Zongsuo Liang; Dongfeng Yang

    2016-01-01

    Although magnesium(Mg) is one of the most important nutrients, involved in many enzyme activities and the structural stabilization of tissues, its importance as a macronutrient ion has been overlooked in recent decades by botanists and agriculturists, who did not regard Mg deficiency(MGD) in plants as a severe health problem. However, recent studies have shown,surprisingly, that Mg contents in historical cereal seeds have markedly declined over time, and two thirds of people surveyed in developed countries received less than their minimum daily Mg requirement. Thus, the mechanisms of response to MGD and ways to increase Mg contents in plants are two urgent practical problems. In this review, we discuss several aspects of MGD in plants, including phenotypic and physiological changes, cell Mg2+homeostasis control by Mg2+transporters, MGD signaling, interactions between Mg2+and other ions, and roles of Mg2+in plant secondary metabolism. Our aim is to improve understanding of the influence of MGD on plant growth and development and to advance crop breeding for Mg enrichment.

  13. Effects of Different Bowl Types and Densities on Grain Yield,Characteristics of Photosynthesis and Dry Mass Production of Bowl Transplanted Japonica Super Rice%不同类型钵苗摆栽密度对粳型超级稻产量及光合物质生产特征的影响

    Institute of Scientific and Technical Information of China (English)

    周兴涛; 张洪程; 许轲; 郭保卫; 陈厚存; 曹利强; 戴其根; 霍中洋; 魏海燕

    2013-01-01

    [Objective] This experiment seeks to maximize the potential of rice bowl seedling planting specifications and reasonable density profile,explore new ways of labor saving and accomplish super high yielding cultivation ofrice.[Method] The experiment was conducted by raising seedling of combinings with 3-bowl,2-bowl and a single bowl seedling discs and using Wuyunjing 24 and Nanjing 44 as materials.Five different rice transplanting densities were designed,and the new bowl seedling planting production potential and the reasonable density were studied.[Result] The treatments of 3-bowl together with 15 × 104 hm-2 holes,2-bowl together with 18× 104 hm-2 holes and a single bowl with 24× 104 hm-2 holes accomplished the highest yield level,while the 2-bowl together with 18× 104 hm-2 holes yielded most among the three treatments.For the different types of bowl seedlings,dry matter accumulation,its proportion of distribution,crop growth rate from heading to maturity stage and grain yield,a pattern at the initial showed a trend of single bowl>2-bowl>3-bowl under the lower basic seedling condition of 36× 104 hm-2,2-bowl>3-bowl and single bowl under the medium basic seedling condition of 72 × 104 hm-2,2-bowl and 3-bowl > single bowl under the larger basic seedling condition of 90× 104 hm-2 to 108 × 104 hm-2.In the three maximum yield conditions,dry matter accumulation,its proportion of distribution and crop growth rate from heading to maturity stage showed a trend of 2-bowl>3-bowl>single bowl.In the same basic seedling conditions,the effective tiller percentage showed a trend of 3-bowl> 2-bowl > single bowl while the decreasing rate of leaf area showed a trend of single bowl> 2-bowl> 3-bowl.Under the three maximum yield conditions,the effective tiller percentage showed a trend of 2-bowl>3-bowl>single bowl while the decreasing rate of leaf area showed a trend of single bowl>3-bowl> 2-bowl.Under the same basic seedling conditions,with the

  14. SuperB Progress Reports Accelerator

    CERN Document Server

    Biagini, Maria Enrica; Boscolo, M; Buonomo, B; Demma, T; Drago, A; Esposito, M; Guiducci, S; Mazzitelli, G; Pellegrino, L; Preger, M A; Raimondi, P; Ricci, R; Rotundo, U; Sanelli, C; Serio, M; Stella, A; Tomassini, S; Zobov, M; Bertsche, K; Brachman, A; Cai, Y; Chao, A; Chesnut, R; Donald, M.H; Field, C; Fisher, A; Kharakh, D; Krasnykh, A; Moffeit, K; Nosochkov, Y; Pivi, M; Seeman, J; Sullivan, M.K; Weathersby, S; Weidemann, A; Weisend, J; Wienands, U; Wittmer, W; Woods, M; Yocky, G; Bogomiagkov, A; Koop, I; Levichev, E; Nikitin, S; Okunev, I; Piminov, P; Sinyatkin, S; Shatilov, D; Vobly, P; Bosi, F; Liuzzo, S; Paoloni, E; Bonis, J; Chehab, R; Le Meur, G; Lepercq, P; Letellier-Cohen, F; Mercier, B; Poirier, F; Prevost, C; Rimbault, C; Touze, F; Variola, A; Bolzon, B; Brunetti, L; Jeremie, A; Baylac, M; Bourrion, O; De Conto, J M; Gomez, Y; Meot, F; Monseu, N; Tourres, D; Vescovi, C; Chanci, A; Napoly, O; Barber, D P; Bettoni, S; Quatraro, D

    2010-01-01

    This report details the present status of the Accelerator design for the SuperB Project. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  15. SuperB Progress Report: Detector

    Energy Technology Data Exchange (ETDEWEB)

    Grauges, E.; /Barcelona U., ECM; Donvito, G.; Spinoso, V.; /INFN, Bari /Bari U.; Manghisoni, M.; Re, V.; Traversi, G.; /INFN, Pavia /Bergamo U., Ingengneria Dept.; Eigen, G.; Fehlker, D.; Helleve, L.; /Bergen U.; Carbone, A.; Di Sipio, R.; Gabrielli, A.; Galli, D.; Giorgi, F.; Marconi, U.; Perazzini, S.; Sbarra, C.; Vagnoni, V.; Valentinetti, S.; Villa, M.; Zoccoli, A.; /INFN, Bologna /Bologna U. /Caltech /Carleton U. /Cincinnati U. /INFN, CNAF /INFN, Ferrara /Ferrara U. /UC, Irvine /Taras Shevchenko U. /Orsay, LAL /LBL, Berkeley /UC, Berkeley /Frascati /INFN, Legnaro /Orsay, IPN /Maryland U. /McGill U. /INFN, Milan /Milan U. /INFN, Naples /Naples U. /Novosibirsk, IYF /INFN, Padua /Padua U. /INFN, Pavia /Pavia U. /INFN, Perugia /Perugia U. /INFN, Perugia /Caltech /INFN, Pisa /Pisa U. /Pisa, Scuola Normale Superiore /PNL, Richland /Queen Mary, U. of London /Rutherford /INFN, Rome /Rome U. /INFN, Rome2 /Rome U.,Tor Vergata /INFN, Rome3 /Rome III U. /SLAC /Tel Aviv U. /INFN, Turin /Turin U. /INFN, Padua /Trento U. /INFN, Trieste /Trieste U. /TRIUMF /British Columbia U. /Montreal U. /Victoria U.

    2012-02-14

    This report describes the present status of the detector design for SuperB. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  16. Heart Transplantation

    Science.gov (United States)

    A heart transplant removes a damaged or diseased heart and replaces it with a healthy one. The healthy heart comes from a donor who has died. It is the last resort for people with heart failure when all other treatments have failed. The ...

  17. Transplant production

    Science.gov (United States)

    For field pepper (Capsicum spp.) production, plants can be established from direct seed or transplants depending on the location and cultural practices for the specific pepper type grown. Direct seeding can result in slow, variable, and reduced plant stands due to variations in soil temperature, wat...

  18. The first two cadaveric renal transplantations in Blida, Algeria.

    Science.gov (United States)

    Si-ahmed, E M

    2011-11-01

    Currently, living related donor renal transplantation is the most common source for transplantation in Algeria. To develop cadaveric organ donation, the Blida Transplantation Team (BTT) started a local education program and campaign. On March 31, 2010, we procured and transplanted 2 kidneys from a 17-year-old brain-dead donor. The BTT is conscious that the local initiative must be followed nationally, with the help of the health authorities. There is an urgent need to promote brain-dead donors and cadaveric organ retriveal throughout the country. It will also be necessary to create national waiting lists for candidates not only for renal, but also for other organ transplantations. Copyright © 2011 Elsevier Inc. All rights reserved.

  19. What's So Super about Superfoods?

    Science.gov (United States)

    ... with meals. The Skinny on Common Super Foods Salmon is a fatty fish that’s low in saturated ... soy nuts are high in polyunsaturated fat, fiber, vitamins and minerals but low in saturated fat. They ...

  20. Super Ministries,Better Administration

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Chinese lawmakers on March 15th endorsed a State Counci l proposal for institutional overhaul of the tentral government,which involves the establishment of"super ministries"concerning energy,transport,industry and environmental protection.

  1. What are super-enhancers?

    Science.gov (United States)

    Pott, Sebastian; Lieb, Jason D

    2015-01-01

    The term 'super-enhancer' has been used to describe groups of putative enhancers in close genomic proximity with unusually high levels of Mediator binding, as measured by chromatin immunoprecipitation and sequencing (ChIP-seq). Here we review the identification and composition of super-enhancers, describe links between super-enhancers, gene regulation and disease, and discuss the functional significance of enhancer clustering. We also provide our perspective regarding the proposition that super-enhancers are a regulatory entity conceptually distinct from what was known before the introduction of the term. Our opinion is that there is not yet strong evidence that super-enhancers are a novel paradigm in gene regulation and that use of the term in this context is not currently justified. However, the term likely identifies strong enhancers that exhibit behaviors consistent with previous models and concepts of transcriptional regulation. In this respect, the super-enhancer definition is useful in identifying regulatory elements likely to control genes important for cell type specification.

  2. Urgent need for warming experiments in tropical forests

    Science.gov (United States)

    Calaveri, Molly A.; Reed, Sasha C.; Smith, W. Kolby; Wood, Tana E.

    2015-01-01

    powerful and urgent way forward in order to improve our understanding of tropical forest responses to climate change.

  3. HESS Opinions "Urgent water challenges are not sufficiently researched"

    Directory of Open Access Journals (Sweden)

    L. P. Darvis

    2009-06-01

    Full Text Available In this opinion paper we submit that water experts conduct comparatively little research on the more urgent challenges facing the global community. Five specific biases are identified. First, research in the field of water and sanitation is heavily biased against sanitation. Second, research on food security is biased in favour of conventional irrigation and fails to address the problems and opportunities of rainfed agriculture. Third, insufficient water research is dedicated to developmental compared to environmental issues. Fourth, too little research is conducted on adaptation to climate change by developing countries. And finally, research on water governance has a fascination for conflict but too little eye for cooperation and meeting basic needs. This paper illustrates these biases with bibliometric indicators extracted from the ISI Web of Science. There is a stark mismatch between the global demand for knowledge and the supply of it. This mismatch is identified here as a problem that we water scientists must confront and resolve. We still lack a full understanding why this divergence between demand and supply occurs and persists; an understanding that is required to guide us towards aligning our research priorities to societal demands. The paper, however, makes some inferences. On the one hand, we should promote the global South to create its own research biases and allow it to develop alternative solutions. Simultaneously we would benefit from critical examination of our own research practice. Although this paper addresses a critical challenge it does not aim to be exhaustive or definitive. We merely identify the persistence of intransigent water problems as a valid research object in itself.

  4. HESS Opinions "Urgent water challenges are not sufficiently researched"

    Science.gov (United States)

    van der Zaag, P.; Gupta, J.; Darvis, L. P.

    2009-06-01

    In this opinion paper we submit that water experts conduct comparatively little research on the more urgent challenges facing the global community. Five specific biases are identified. First, research in the field of water and sanitation is heavily biased against sanitation. Second, research on food security is biased in favour of conventional irrigation and fails to address the problems and opportunities of rainfed agriculture. Third, insufficient water research is dedicated to developmental compared to environmental issues. Fourth, too little research is conducted on adaptation to climate change by developing countries. And finally, research on water governance has a fascination for conflict but too little eye for cooperation and meeting basic needs. This paper illustrates these biases with bibliometric indicators extracted from the ISI Web of Science. There is a stark mismatch between the global demand for knowledge and the supply of it. This mismatch is identified here as a problem that we water scientists must confront and resolve. We still lack a full understanding why this divergence between demand and supply occurs and persists; an understanding that is required to guide us towards aligning our research priorities to societal demands. The paper, however, makes some inferences. On the one hand, we should promote the global South to create its own research biases and allow it to develop alternative solutions. Simultaneously we would benefit from critical examination of our own research practice. Although this paper addresses a critical challenge it does not aim to be exhaustive or definitive. We merely identify the persistence of intransigent water problems as a valid research object in itself.

  5. Logistics and outcome in urgent and emergency colorectal surgery.

    Science.gov (United States)

    Elshove-Bolk, J; Ellensen, V S; Baatrup, G

    2010-10-01

    Infrastructure-related factors are seldom described in detail in studies on outcome after surgical procedures. We studied patient, procedure, physician and infrastructure characteristics and their effect on outcome at a Norwegian University hospital. All patients admitted between 1st January 2002 and 30th June 2003 who underwent urgent or emergency colorectal surgery were extracted from the hospital databases and retrospectively analysed. There were 196 patients. The overall complication rate was 39%. Forty-six (24%) patients died during admission after surgery. Those who died were less likely to be operated by a subspecialized colorectal surgeon (17%vs 30%, P = 0.001). The anaesthesiologist was a resident in most of the cases (> 75%) for both those who survived and those who died. Surgery performed out-of-office hours was common in both groups, although the patients who died were more likely to be operated upon at night (28%vs 18%, P = 0.001). The time interval standard from admission to surgery was met in only 84 (43%) patients. Forty-nine (49/196, 25%) procedures were delayed beyond the time requested by the surgeon by more than 120 min (mean 363 min). The outcome after emergency colorectal surgery was consistent with the literature but the infrastructure was not optimal. Improvements may be achieved by a focus on decreasing waiting times, abandoning of out-of-office emergency surgery and increasing the involvement of senior staff. © 2010 The Authors. Colorectal Disease © 2010 The Association of Coloproctology of Great Britain and Ireland.

  6. Holography based super resolution

    Science.gov (United States)

    Hussain, Anwar; Mudassar, Asloob A.

    2012-05-01

    This paper describes the simulation of a simple technique of superresolution based on holographic imaging in spectral domain. The input beam assembly containing 25 optical fibers with different orientations and positions is placed to illuminate the object in the 4f optical system. The position and orientation of each fiber is calculated with respect to the central fiber in the array. The positions and orientations of the fibers are related to the shift of object spectrum at aperture plane. During the imaging process each fiber is operated once in the whole procedure to illuminate the input object transparency which gives shift to the object spectrum in the spectral domain. This shift of the spectrum is equal to the integral multiple of the pass band aperture width. During the operation of single fiber (ON-state) all other fibers are in OFF-state at that time. The hologram recorded by each fiber at the CCD plane is stored in computer memory. At the end of illumination process total 25 holograms are recorded by the whole fiber array and by applying some post processing and specific algorithm single super resolved image is obtained. The superresolved image is five times better than the band-limited image. The work is demonstrated using computer simulation only.

  7. My approach to cardiothoracic transplantation and the role of the histocompatibility and immunogenetics laboratory in a rapidly developing field.

    Science.gov (United States)

    Carter, Vaughan

    2010-03-01

    Cardiothoracic transplantation presents specific challenges. The lack of long-term replacement therapy (such as dialysis for kidney patients) creates a more urgent situation than for other forms of transplantation, necessitating a different approach. This review looks at ways in which the challenges are being met and the integral role of the histocompatibility and immunogenetics laboratory.

  8. Liver Transplant: Nutrition

    Science.gov (United States)

    ... ZIP code here Enter ZIP code here Liver Transplant: Nutrition for Veterans and the Public Nutrition Liver ... apply to transplant and liver disease patients. Pre-Transplant Protein Malnutrition -- Many patients with end stage liver ...

  9. Transplant Center Search Form

    Science.gov (United States)

    ... Share Your Story Give Us Feedback - A + A Transplant Center Search Form Welcome to the Blood & Marrow ... transplant centers for patients with a particular disease. Transplant Center login Username: * Password: * Request new password Join ...

  10. Urgent Care Facilities, Urgent Care Facilities in Iredell County, NC, Published in 2007, 1:2400 (1in=200ft) scale, Iredell County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Urgent Care Facilities dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Orthoimagery information as of 2007. It is described as...

  11. Effects of Different Types of Bowl Seedlings and Densities on Characteristics of Nitrogen Uptake, Utilization and Translocation of Bowl Transplanted Japonica Super Rice%不同类型钵苗及摆栽密度对粳型超级稻氮素吸收利用与转运特征的影响

    Institute of Scientific and Technical Information of China (English)

    许轲; 周兴涛; 曹利强; 张洪程; 郭保卫; 陈厚存; 吴中华; 朱聪聪; 杨岩

    2013-01-01

    [Objective] The objective of this experiment was to identify the differences in N absorption and use efficiency of three different bowl types and densities in bowl transplanted rice. [Method] The experiment was conducted by the seedlings of 3-bowl combined together, 2-bowl combined together and single bowl seedling disc with Wuyunjing 24 and Nanjing 44 as materials, and the setting of different transplanting densities. The differences in N absorption, use efficiency and their relationship with yield were studied. [Result] For the same type of bowl seedlings, N uptake amount at heading and maturity stages, recovery efficiency, agronomic efficiency, partial factor productivity increased first and then decreased with the increase of the basic seedlings number. Under the same basic seedling conditions, the N uptake amount at heading and maturity stages, recovery efficiency, agronomic efficiency and partial factor productivity showed the following rules:the lower basic seedling number condition of 36×104·hm-2 to 54×104·hm-2 showed a trend of single bowl>2-bowl>3-bowl, the medium basic seedling number condition of 72×104·hm-2 showed a trend of 2-bowl>single bowl>3-bowl, while the larger basic seedling number condition of 90×104·hm-2 to 108×104·hm-2 showed a trend of 2-bowl and 3-bowl>single bowl. Under the three maximum yield conditions, the N uptake at heading and maturity stages, recovery efficiency, agronomic efficiency and partial factor productivity showed a trend of 2-bowl>3-bowl>single bowl. Correlation analysis of the three maximum yield treatments indicated that there existed a significant or a highly significant positive correlation between yield and N uptake of leaves and aboveground at maturity stage, N uptake from jointing to heading stage and heading to maturity stage.[Conclusion]Under the suitable or larger basic seedling number conditions, compared with single bowl cultivation, 3-bowl and 2-bowl, especially the 2-bowl seedling planting methods

  12. Electrically tuned super-capacitors

    CERN Document Server

    Chowdhury, Tazima S

    2015-01-01

    Fast charging and discharging of large amounts of electrical energy make super-capacitors ideal for short-term energy storage [1-5]. In its simplest form, the super-capacitor is an electrolytic capacitor made of an anode and a cathode immersed in an electrolyte. As for an ordinary capacitor, minimizing the charge separation distance and increasing the electrode area increase capacitance. In super-capacitors, charge separation is of nano-meter scale at each of the electrode interface (the Helmholtz double layer). Making the electrodes porous increases their effective surface area [6-8]. A separating layer between the anode and the cathode electrodes is used to minimize unintentional electrical discharge (Figure 1). Here we show how to increase the capacitance of super-capacitors by more than 45 percent when modifying the otherwise passive separator layer into an active diode-like structure. Active control of super-capacitors may increase their efficiency during charge and discharge cycles. Controlling ion flow...

  13. Quantization of super Teichmueller spaces

    Energy Technology Data Exchange (ETDEWEB)

    Aghaei, Nezhla

    2016-08-15

    The quantization of the Teichmueller spaces of Riemann surfaces has found important applications to conformal field theory and N=2 supersymmetric gauge theories. We construct a quantization of the Teichmueller spaces of super Riemann surfaces, using coordinates associated to the ideal triangulations of super Riemann surfaces. A new feature is the non-trivial dependence on the choice of a spin structure which can be encoded combinatorially in a certain refinement of the ideal triangulation. We construct a projective unitary representation of the groupoid of changes of refined ideal triangulations. Therefore, we demonstrate that the dependence of the resulting quantum theory on the choice of a triangulation is inessential. In the quantum Teichmueller theory, it was observed that the key object defining the Teichmueller theory has a close relation to the representation theory of the Borel half of U{sub q}(sl(2)). In our research we observed that the role of U{sub q}(sl(2)) is taken by quantum superalgebra U{sub q}(osp(1 vertical stroke 2)). A Borel half of U{sub q}(osp(1 vertical stroke 2)) is the super quantum plane. The canonical element of the Heisenberg double of the quantum super plane is evaluated in certain infinite dimensional representations on L{sup 2}(R) x C{sup 1} {sup vertical} {sup stroke} {sup 1} and compared to the flip operator from the Teichmueller theory of super Riemann surfaces.

  14. Super-Virasoro anomaly, super-Weyl anomaly and the super-Liouville action for 2D supergravity

    CERN Document Server

    Fujiwara, T; Suzuki, T; Fujiwara, Takanori; Igarashi, Hiroshi; Suzuki, Tadao

    1996-01-01

    The relation between super-Virasoro anomaly and super-Weyl anomaly in N=1 NSR superstring coupled with 2D supergravity is investigated from canonical theoretical view point. The WZW action canceling the super-Virasoro anomaly is explicitly constructed. It is super-Weyl invariant but nonlocal functional of 2D supergravity. The nonlocality can be remedied by the super-Liouvlle action, which in turn recovers the super-Weyl anomaly. The final gravitational effective action turns out to be local but noncovariant super-Liouville action, describing the dynamical behavior of the super-Liouville fields. The BRST invariance of this approach is examined in the superconformal gauge and in the light-cone gauge.

  15. The Super-Kamiokande Experiment

    CERN Document Server

    Walter, C W

    2008-01-01

    Super-Kamiokande is a 50 kiloton water Cherenkov detector located at the Kamioka Observatory of the Institute for Cosmic Ray Research, University of Tokyo. It was designed to study neutrino oscillations and carry out searches for the decay of the nucleon. The Super-Kamiokande experiment began in 1996 and in the ensuing decade of running has produced extremely important results in the fields of atmospheric and solar neutrino oscillations, along with setting stringent limits on the decay of the nucleon and the existence of dark matter and astrophysical sources of neutrinos. Perhaps most crucially, Super-Kamiokande for the first time definitively showed that neutrinos have mass and undergo flavor oscillations. This chapter will summarize the published scientific output of the experiment with a particular emphasis on the atmospheric neutrino results.

  16. Microsphere Super-resolution Imaging

    CERN Document Server

    Wang, Zengbo

    2015-01-01

    Recently, it was discovered that microsphere can generate super-resolution focusing beyond diffraction limit. This has led to the development of an exciting super-resolution imaging technique -microsphere nanoscopy- that features a record resolution of 50 nm under white lights. Different samples have been directly imaged in high resolution and real time without labelling, including both non-biological (nano devices, structures and materials) and biological (subcellular details, viruses) samples. This chapter reviews the technique, which covers its background, fundamentals, experiments, mechanisms as well as the future outlook.

  17. Interactive Super Mario Bros Evolution

    DEFF Research Database (Denmark)

    Sørensen, Patrikk D.; Olsen, Jeppeh M.; Risi, Sebastian

    2016-01-01

    to encourage the evolution of desired behaviors. In this paper, we show how casual users can create controllers for \\emph{Super Mario Bros} through an interactive evolutionary computation (IEC) approach, without prior domain or programming knowledge. By iteratively selecting Super Mario behaviors from a set...... of candidates, users are able to guide evolution towards a variety of different behaviors, which would be difficult with an automated approach. Additionally, the user-evolved controllers perform similarly well as controllers evolved with a traditional fitness-based approach when comparing distance traveled...

  18. Quantisation of super Teichmueller theory

    Energy Technology Data Exchange (ETDEWEB)

    Aghaei, Nezhla [DESY Hamburg (Germany). Theory Group; Hamburg Univ. (Germany). Dept. of Mathematics; Pawelkiewicz, Michal; Techner, Joerg [DESY Hamburg (Germany). Theory Group

    2015-12-15

    We construct a quantisation of the Teichmueller spaces of super Riemann surfaces using coordinates associated to ideal triangulations of super Riemann surfaces. A new feature is the non-trivial dependence on the choice of a spin structure which can be encoded combinatorially in a certain refinement of the ideal triangulation. By constructing a projective unitary representation of the groupoid of changes of refined ideal triangulations we demonstrate that the dependence of the resulting quantum theory on the choice of a triangulation is inessential.

  19. Quantisation of super Teichmueller theory

    CERN Document Server

    Aghaei, Nezhla; Teschner, Joerg

    2015-01-01

    We construct a quantisation of the Teichmueller spaces of super Riemann surfaces using coordinates associated to ideal triangulations of super Riemann surfaces. A new feature is the non-trivial dependence on the choice of a spin structure which can be encoded combinatorially in a certain refinement of the ideal triangulation. By constructing a projective unitary representation of the groupoid of changes of refined ideal triangulations we demonstrate that the dependence of the resulting quantum theory on the choice of a triangulation is inessential.

  20. The construction of orthodox super rpp semigroups

    Institute of Scientific and Technical Information of China (English)

    HE Yong; GUO Yuqi; Kar Ping Shum

    2004-01-01

    We define orthodox super rpp semigroups and study their semilattice decompositions. Standard representation theorem of orthodox super rpp semigroups whose subband of idempotents is in the varieties of bands described by an identity with at most three variables are obtained.

  1. 78 FR 9569 - Unexpected Urgent Refugee and Migration Needs Relating to Syria

    Science.gov (United States)

    2013-02-08

    ...--Unexpected Urgent Refugee and Migration Needs Relating to Syria Memorandum of January 31, 2013--Delegation of... Determination No. 2013-04 of January 29, 2013 Unexpected Urgent Refugee and Migration Needs Relating to Syria... the crisis in Syria. You are authorized and directed to publish this memorandum in the...

  2. A strategic-interaction analysis of an urgent appeal system and its outcomes for garment workers

    NARCIS (Netherlands)

    den Hond, F; Stolwijk, S.; Merk, J.

    2014-01-01

    Within the global garment industry the term "urgent appeal" is used to describe a request for action to Western activist groups for support in a specific case of labor rights violations. The urgent appeal system has become an important strategy for the transnational antisweatshop movement. It is dis

  3. 3 CFR - Unexpected Urgent Refugee and Migration Needs Related to the Continuing Conflict in Pakistan

    Science.gov (United States)

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Unexpected Urgent Refugee and Migration Needs... Presidential Determination No. 2009-16 of March 11, 2009 Unexpected Urgent Refugee and Migration Needs Related... Migration and Refugee Assistance Act of 1962 (the “Act”), as amended (22 U.S.C. 2601), I hereby...

  4. 3 CFR - Unexpected Urgent Refugee and Migration Needs Related to Gaza

    Science.gov (United States)

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Unexpected Urgent Refugee and Migration Needs... of January 27, 2009 Unexpected Urgent Refugee and Migration Needs Related to Gaza Memorandum for the..., including section 2(c)(1) of the Migration and Refugee Assistance Act of 1962 (the “Act”), as amended (22...

  5. A strategic-interaction analysis of an urgent appeal system and its outcomes for garment workers

    NARCIS (Netherlands)

    den Hond, F; Stolwijk, S.; Merk, J.

    2014-01-01

    Within the global garment industry the term "urgent appeal" is used to describe a request for action to Western activist groups for support in a specific case of labor rights violations. The urgent appeal system has become an important strategy for the transnational antisweatshop movement. It is

  6. 淮北地区机插超级粳稻产量形成及氮素吸收利用特征%The Yield Formation, Nitrogen Absorption and Utilization of Mechanical Transplanting Su-per Japonica Rice in Huaibei Area

    Institute of Scientific and Technical Information of China (English)

    梁健; 李晓峰; 舒鹏; 张洪程; 霍中洋; 戴其根; 许轲; 魏海燕; 郭保卫

    2016-01-01

    The aim for this study was to research the yield formation and characteristics of nitrogen utilization about super japonica rice in Huaibei Area. A field experiment was conducted using medium-maturing medium super japonica rice and non-super japonica rice cultivars(contrast) as materials, investigating the effects of different nitrogen application levels(0, 225, 300 kg/hm2). The results showed that, with the increase of N application amount, the grain yield of super japonica rice increased continuously. The highest av-erage grain yield of the super japonica rice cultivars was 10.98% higher than that of the contrast. Compared with the contrast, more grains per panicle and population spikelets (4.8×108/hm2) were observed in super japonica rice,with the same level of seed setting rate and thousand seed weight. The numbers of stems and tillers of super japonica rice grow earlier and faster, and the percentage of productive tillers was higher. The leaf area index and photosynthetic potential of super japonica rice was relatively low before jointing stage, and increased significantly after jointing stage. Compared with the contrast, the grain-leaf ratio of super japonica rice was higher in 3 nitrogen application levels. Compared with the contrast, the dry matter accumulation of super japonica rice was relatively lower before jointing stage, but 7.77% higher at jointing-heading stage, 6.96% higher at heading-maturity stage respectively. The N accu-mulations and N uptake rates of super japonica rice were higher than the contrast at every stage. This study showed that, in 3 nitrogen application levels, the super japonica rice showed obvious advantage to production in Huaibei Area. Compared with the non-super japonica rice, super japonica rice has more grains per panicle and population spikelets. And the leaf area index, photosynthetic poten-tial, grain-leaf ratio, total dry matter accumulation and percentage of productive tillers were high. The reason why the yield of medi

  7. Super-resolution Phase Tomography

    KAUST Repository

    Depeursinge, Christian

    2013-04-21

    Digital Holographic Microscopy (DHM) yields reconstructed complex wavefields. It allows synthesizing the aperture of a virtual microscope up to 2π, offering super-resolution phase images. Live images of micro-organisms and neurons with resolution less than 100 nm are presented.

  8. Super Rice Breeding in China

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@I. Demand for super high yield rice in China   Rice is one of the main staple food in China. The performance of rice sector in production and yield had been very impressive in the last four decades. However, rice production and yield has stagnated since 1990.

  9. Super Girls Still Center Stage

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The TV singing contest continues to draw a devoted audience, but will its impact on Chinese culture fall away like a shooting star? Ask any teenage girl in China to name the finalists of last year's Super Girl show and chances are she will instantly come up with the three big names.She'll probable

  10. Analysis of Forensic Super Timelines

    Science.gov (United States)

    2012-06-14

    BIB .1  vii List of Figures Figure Page...Hacker disconnects from User’s system  User clicks off Screen Saver  User closes Solitaire program  User logs off system BIB .1...analysis- tapestry_33836. BIB .2 Guðjónsson, K. (2010). Mastering the super timeline with log2timeline. SANS Gold Paper accepted June 29,2010

  11. Clinical outcome of acute nonvariceal upper gastrointestinal bleeding after hours: the role of urgent endoscopy.

    Science.gov (United States)

    Ahn, Dong-Won; Park, Young Soo; Lee, Sang Hyub; Shin, Cheol Min; Hwang, Jin-Hyeok; Kim, Jin-Wook; Jeong, Sook-Hyang; Kim, Nayoung; Lee, Dong Ho

    2016-05-01

    This study was performed to investigate the clinical role of urgent esophagogastroduodenoscopy (EGD) for acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) performed by experienced endoscopists after hours. A retrospective analysis was performed for consecutively collected data of patients with ANVUGIB between January 2009 and December 2010. A total of 158 patients visited the emergency unit for ANVUGIB after hours. Among them, 60 underwent urgent EGD (within 8 hours) and 98 underwent early EGD (8 to 24 hours) by experienced endoscopists. The frequencies of hemodynamic instability, fresh blood aspirate on the nasogastric tube, and high-risk endoscopic findings were significantly higher in the urgent EGD group. Primary hemostasis was achieved in all except two patients. There were nine cases of recurrent bleeding, and 30-day mortality occurred in three patients. There were no significant differences between the two groups in primary hemostasis, recurrent bleeding, and 30-day mortality. In a multiple linear regression analysis, urgent EGD significantly reduced the hospital stay compared with early EGD. In patients with a high clinical Rockall score (more than 3), urgent EGD tended to decrease the hospital stay, although this was not statistically significant (7.7 days vs. 12.0 days, p > 0.05). Urgent EGD after hours by experienced endoscopists had an excellent endoscopic success rate. However, clinical outcomes were not significantly different between the urgent and early EGD groups.

  12. Super-translations and super-rotations at the horizon

    CERN Document Server

    Donnay, Laura; Gonzalez, Hernan A; Pino, Miguel

    2015-01-01

    We show that the asymptotic symmetries close to non-extremal black hole horizons are generated by an extension of super-translations. This group is generated by a semi-direct sum of Virasoro and abelian currents. The charges associated to the asymptotic Killing symmetries satisfy the same algebra. When considering the special case of the stationary black hole, the zero mode charges correspond to the angular momentum and the entropy at the horizon.

  13. Imaging strategies for detection of urgent conditions in patients with acute abdominal pain: diagnostic accuracy study

    Science.gov (United States)

    Laméris, Wytze; van Randen, Adrienne; van Es, H Wouter; van Heesewijk, Johannes P M; van Ramshorst, Bert; Bouma, Wim H; ten Hove, Wim; van Leeuwen, Maarten S; van Keulen, Esteban M; Dijkgraaf, Marcel G W; Bossuyt, Patrick M M; Boermeester, Marja A

    2009-01-01

    Objective To identify an optimal imaging strategy for the accurate detection of urgent conditions in patients with acute abdominal pain. Design Fully paired multicentre diagnostic accuracy study with prospective data collection. Setting Emergency departments of two university hospitals and four large teaching hospitals in the Netherlands. Participants 1021 patients with non-traumatic abdominal pain of >2 hours’ and <5 days’ duration. Exclusion criteria were discharge from the emergency department with no imaging considered warranted by the treating physician, pregnancy, and haemorrhagic shock. Intervention All patients had plain radiographs (upright chest and supine abdominal), ultrasonography, and computed tomography (CT) after clinical and laboratory examination. A panel of experienced physicians assigned a final diagnosis after six months and classified the condition as urgent or non-urgent. Main outcome measures Sensitivity and specificity for urgent conditions, percentage of missed cases and false positives, and exposure to radiation for single imaging strategies, conditional imaging strategies (CT after initial ultrasonography), and strategies driven by body mass index and age or by location of pain. Results 661 (65%) patients had a final diagnosis classified as urgent. The initial clinical diagnosis resulted in many false positive urgent diagnoses, which were significantly reduced after ultrasonography or CT. CT detected more urgent diagnoses than did ultrasonography: sensitivity was 89% (95% confidence interval 87% to 92%) for CT and 70% (67% to 74%) for ultrasonography (P<0.001). A conditional strategy with CT only after negative or inconclusive ultrasonography yielded the highest sensitivity, missing only 6% of urgent cases. With this strategy, only 49% (46% to 52%) of patients would have CT. Alternative strategies guided by body mass index, age, or location of the pain would all result in a loss of sensitivity. Conclusion Although CT is the most

  14. Performance of super hybrid rice cultivars grown under no-tillage and direct seeding

    Directory of Open Access Journals (Sweden)

    Min Huang

    2012-04-01

    Full Text Available Good progress has been made in the super hybrid rice (Oryza sativa L. breeding in China. However, rice yield not only depends on the genetic characteristics but also on the agronomic practices. No-tillage and direct seeding (NTDS is a simplified cultivation technology that greatly simplifies both land preparation and crop establishment. Aiming to determine the grain yield performance of super hybrid rice under NTDS and to identify critical factors that determine grain yield, field experiments were conducted in Nanxian, Hunan Province, China in 2009 and 2010. Two super hybrid cultivars, Liangyoupeijiu and Y-liangyou 1, were grown under conventional tillage and transplanting (CTTP and NTDS. Grain yield, yield components, biomass production, crop growth rate and biomass accumulation during sowing to heading (HD and HD to maturity were measured for each cultivar. There was no difference in grain yield under NTDS and CTTP. However, grain yield differed with cultivar and year. Y-liangyou 1 produced 4 % higher grain yield than Liangyoupeijiu in 2009, whereas in 2010 both cultivars yielded similarly. Grain yields of both cultivars were higher in 2009 than in 2010. Higher grain yield of Y-liangyou 1 in 2009 was associated with higher spikelet filling (spikelet filling percentage and grain weight, which resulted from higher biomass production. Crop growth rate after HD was critical for biomass production by the super hybrid rice. We suggest that increasing the crop growth rate after HD is an effective approach to increase grain yield of super hybrid rice under NTDS.

  15. Transplantation Immunity. Contemporary Views.

    Science.gov (United States)

    Zaretskaya, Yuliya M.

    1999-12-01

    "Transplantation immunity in Cyclosporin era" is a special chapter in science under name transplantation immunity. Nowadays, practically all the organs can be grafted: kidney, heart, lung, liver, pancreas both as organ, and as islet cells, bone marrow from relative and unrelative donors. The broad spectrum of grafted organs gave one more surprising peculiarity of transplantation immunity: it operates with different strength after transplantation of various organs. If the decreasing gradient of transplantation immunity could be composed, then it appeared to be approximately in the following order: bone marrow - skin - kidney - heart - lung. The most complicated operating activity of transplantation immunity is occurring after bone marrow transplantation, especially from unrelative donor, because in bone marrow transplantation immunological process develops in both directions. Therefore now, bone marrow is the only organ (tissue), when the complete compatibility between donor and recipient is required after its transplantation; especially in cases with unrelative donors.

  16. Organ transplantation in Tunisia.

    Science.gov (United States)

    El Matri, Aziz; Ben Abdallah, Taieb

    2015-04-01

    Kidney transplants were first performed in Tunisia in 1986, and transplants soon extended to other organs including the heart, liver, and pancreas. Live-related donor and deceased-donor kidney transplants were both began in the summer of 1986. An organ procurement and transplant law was passed in March 1991, and the National Centre for Advancement of Organ Transplantation was created in 1995. The number of transplantation units has increased to 7 throughout the country, and the yearly transplant number has progressively increased to 139 in 2010, including 20% from deceased kidney donors. Despite these gains, the need continues to grow. Heart transplants began in January 1993, and Tunisia and Jordan are currently the only Arab countries where it is practiced. However, only 16 patients have received a heart transplant as of 2004, and the number of recipients has decreased in the past 10 years. Liver transplants are rare in other Arab countries, but began in Tunisia in January 1998. Over 10 years, 38 patients benefited from this procedure. After a few years of stagnation, the number of liver transplants is increasing. While all types of transplantation are needed, kidney transplantation is a priority in Tunisia. The target is to perform 400 transplants annually, which would require a long-term strategy to provide full financial coverage using the National Health Insurance Funds in both the public and private sectors.

  17. 212. Incidencia de complicaciones graves en trasplantes cardíacos urgentes y no urgentes. 10 años de experiencia

    Directory of Open Access Journals (Sweden)

    L. Donate Bertolín

    2010-01-01

    Conclusiones: En nuestra serie, el trasplante urgente no presentó una mayor mortalidad perioperatoria. Sin embargo, observamos mayor número de complicaciones graves, asociadas a mortalidad a más largo plazo, como FAI, infección bacteriana y ventilación mecánica prolongada.

  18. [The Declaration of Istanbul on organ trafficking and transplant tourism].

    Science.gov (United States)

    2009-01-01

    A Summit Meeting that convened over 150 representatives of scientific and medical bodies from around the world was held in Istanbul from April 30 to May 2, 2008 to address the urgent and growing problem of organ sales, transplant tourism and trafficking in organ donors in the context of the global shortage of organs. Preparatory work for the meeting was undertaken by a Steering Committee convened by The Transplantation Society and the International Society of Nephrology in Dubai in December 2007. Participants at the Istanbul Summit were selected by the Steering Committee according to the following criteria: The country liaisons with The Transplantation Society representing virtually all countries with transplantation programs; representatives from international societies and the Vatican; key stakeholders in nephrology and transplantation; public policy experts in organ transplantation; and ethicists, anthropologists, sociologists, and legal academic well-recognized for their work on transplantation policy and practice. This Declaration represents the consensus of the Summit participants and is an authorized Spanish translation that will help disseminate this information among Mexican health professionals and interested readers.

  19. 伦敦SuperDesign展

    Institute of Scientific and Technical Information of China (English)

    柚子

    2011-01-01

    近日,英国伦敦Super Design展在伦敦Wakefield大街的The Dairy展厅如期举行。本次展览展出了来自包括知名设计师和新兴设计师的特别定制的工作室作品:到如今已经是第五个年头的伦敦Super Deslgn展,力图强发展,展出形式别出心裁、独树一帜,从一个崭新.活跃的角度集展示当代艺术。

  20. Super-stable Poissonian structures

    Science.gov (United States)

    Eliazar, Iddo

    2012-10-01

    In this paper we characterize classes of Poisson processes whose statistical structures are super-stable. We consider a flow generated by a one-dimensional ordinary differential equation, and an ensemble of particles ‘surfing’ the flow. The particles start from random initial positions, and are propagated along the flow by stochastic ‘wave processes’ with general statistics and general cross correlations. Setting the initial positions to be Poisson processes, we characterize the classes of Poisson processes that render the particles’ positions—at all times, and invariantly with respect to the wave processes—statistically identical to their initial positions. These Poisson processes are termed ‘super-stable’ and facilitate the generalization of the notion of stationary distributions far beyond the realm of Markov dynamics.

  1. Super-Kamiokande atmospheric neutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Moriyama, S. [Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo, Higashi Mozumi, Hida city, Gifu prefecture (Japan)

    2005-08-15

    Results on atmospheric neutrino analysis at Super-Kamiokande I is presented. The whole data set of atmospheric neutrino sample in Super-Kamiokande I is consistently explained with an assumption of pure {nu}{sub {mu}}-{nu}{sub {tau}} oscillations. The allowed range of parameters is 1.5x10{sup -3}<{delta}m{sup 2}<3.4x10{sup -3} eV{sup 2} and sin{sup 2}2{theta}>0.92 at 90% C.L. In the oscillation analysis, we improved the treatment of systematic errors so that they can be considered as independent. This makes possible to find which systematic errors have larger effect on the analysis results. Some sensitivity studies under several assumptions of improvements in systematic errors are presented.

  2. The Era of Super Capitalism

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The world has entered the "super capitalism" era when one third of its economic activities are controlled by less than 3 percent of global financial capital. This year,a global economic recession,triggered by the U.S. subprime mortgage crisis,seems unavoidable. To tackle international financial problems,Tao Dong,Chief Economist for Asia at Credit Suisse First Boston in Hong Kong,shared his insights with China Business Journal. Excerpts follow.

  3. The effect of health and dental insurance on US children's dental care utilization for urgent and non-urgent dental problems - 2008.

    Science.gov (United States)

    Naavaal, Shillpa; Barker, Laurie K; Griffin, Susan O

    2017-12-01

    We examined the association between utilization of care for a dental problem (utilization-DP) and parent-reported dental problem (DP) urgency among children with DP by type of health care insurance coverage. We used weighted 2008 National Health Interview Survey data from 2,834 children, aged 2-17 years with at least one DP within the 6 months preceding survey. Explanatory variables were selected based on Andersen's model of healthcare utilization. Need was considered urgent if DP included toothache, bleeding gums, broken or missing teeth, broken or missing filling, or decayed teeth and otherwise as non-urgent. The primary enabling variable, insurance, had four categories: none, private health no dental coverage (PHND), private health and dental (PHD), or Medicaid/State Children's Health Insurance Program (SCHIP). Predisposing variables included sociodemographic characteristics. We used bivariate and multivariate analyses to identify explanatory variables' association with utilization-DP. Using logistic regression, we obtained adjusted estimates of utilization-DP by urgency for each insurance category. In bivariate analyses, utilization-DP was associated with both insurance and urgency. In multivariate analyses, the difference in percent utilizing care for an urgent versus non-urgent DP among children covered by Medicaid/SCHIP was 32 percentage points; PHD, 25 percentage points; PHND, 12 percentage points; and no insurance, 14 percentage points. The difference in utilization by DP urgency was higher for children with Medicaid/SCHIP compared with either PHND or uninsured children. Expansion of Medicaid/SCHIP may permit children to receive care for urgent DPs who otherwise may not, due to lack of dental insurance. © 2016 American Association of Public Health Dentistry.

  4. BEWARE OF...SUPER GLUES!!

    CERN Multimedia

    2006-01-01

    What happened? A number of accidents have occurred with the use of 'Super Glues'. Some individuals have suffered injuries - severe irritation, or skin bonded together - through getting glue on their face and in their eyes. What are the hazards associated with glues? 'Super Glues' (i.e. cyanoacrylates): Are harmful if swallowed and are chemical irritants to the eyes, respiratory system and skin. Present the risk of polymerization (hardening) leading to skin damage. Be careful ! 'Super Glues' can bond to skin and eyes in seconds. Note: Other glues, resins and hardeners are also chemicals and as such can cause serious damage to the skin, eyes, respiratory or digestive tract. (For example: some components can be toxic, harmful, corrosive, sensitizing agents, etc.). How to prevent accidents in the future? Read the Material Safety Data Sheet (MSDS) for all of the glues you work with. Check the label on the container to find out which of the materials you work with are hazardous. Wear the right Per...

  5. Super-Eccentric Migrating Jupiters

    CERN Document Server

    Socrates, Aristotle; Dong, Subo; Tremaine, Scott

    2011-01-01

    An important class of formation theories for hot Jupiters involves the excitation of extreme orbital eccentricity (e=0.99 or even larger) followed by tidal dissipation at periastron passage that eventually circularizes the planetary orbit at a period less than 10 days. In a steady state, this mechanism requires the existence of a significant population of super-eccentric (e>0.9) migrating Jupiters with long orbital periods and periastron distances of only a few stellar radii. For these super-eccentric planets, the periastron is fixed due to conservation of orbital angular momentum and the energy dissipated per orbit is constant, implying that the rate of change in semi-major axis a is \\dot a \\propto a^0.5 and consequently the number distribution satisfies dN/dlog a\\propto a^0.5. If this formation process produces most hot Jupiters, Kepler should detect several super-eccentric migrating progenitors of hot Jupiters, allowing for a test of high-eccentricity migration scenarios.

  6. SUPER-ECCENTRIC MIGRATING JUPITERS

    Energy Technology Data Exchange (ETDEWEB)

    Socrates, Aristotle; Katz, Boaz; Dong Subo; Tremaine, Scott [Institute for Advanced Study, Princeton, NJ 08540 (United States)

    2012-05-10

    An important class of formation theories for hot Jupiters involves the excitation of extreme orbital eccentricity (e = 0.99 or even larger) followed by tidal dissipation at periastron passage that eventually circularizes the planetary orbit at a period less than 10 days. In a steady state, this mechanism requires the existence of a significant population of super-eccentric (e > 0.9) migrating Jupiters with long orbital periods and periastron distances of only a few stellar radii. For these super-eccentric planets, the periastron is fixed due to conservation of orbital angular momentum and the energy dissipated per orbit is constant, implying that the rate of change in semi-major axis a is a-dot {proportional_to}a{sup 1/2} and consequently the number distribution satisfies dN/d log a{proportional_to}a{sup 1/2}. If this formation process produces most hot Jupiters, Kepler should detect several super-eccentric migrating progenitors of hot Jupiters, allowing for a test of high-eccentricity migration scenarios.

  7. Transplante de intestino delgado Small intestine transplantation

    Directory of Open Access Journals (Sweden)

    Flávio Henrique Ferreira Galvão

    2003-06-01

    Full Text Available RACIONAL: Avanços da biotecnologia e o desenvolvimento de novas drogas imunossupressoras melhoraram os resultados do transplante de intestino delgado. Esse transplante é atualmente indicado para casos especiais da falência intestinal. OBJETIVO: A presente revisão realça os recentes desenvolvimentos na área do transplante de intestino delgado. MATERIAL E MÉTODO: Mais de 600 publicações de transplante de intestino delgado foram revisadas. O desenvolvimento da pesquisa, novas estratégias de imunossupressão, monitorização do enxerto e do receptor, e avanços na técnica cirúrgica são discutidos. RESULTADOS: Realizaram-se cerca de 700 transplante de intestino delgado em 55 centros: 44% intestino-fígado, 41% enxerto intestinal isolado e 15% transplante multivisceral. Rejeição e infecção são as principais limitações desse transplante. Sobrevida de 5 anos na experiência internacional é de 46% para o transplante de intestino isolado, 43% para o intestino-fígado e de cerca de 30% para o transplante multivisceral. Sobrevidas prolongadas são mais freqüentes nos centros com maior experiência. Em série de 165 transplantes intestinais na Universidade de Pittsburgh, PA, EUA, foi relatada sobrevida do paciente maior do que 75% no primeiro ano, 54% em 5 anos e 42% em 10 anos. Mais de 90% desses pacientes assumem dieta oral irrestrita. CONCLUSÃO: O transplante de intestino delgado evoluiu de estratégia experimental para uma alternativa viável no tratamento da falência intestinal permanente. Promover o refinamento da terapia imunossupressora, do manejo e prevenção de infecções, da técnica cirúrgica e da indicação e seleção adequada dos pacientes é crucial para melhorar a sobrevida desse transplante.BACKGROUND: Significant progress has been made in clinical small bowel transplantation over the last decade mainly due advances in biotechnology and new immunosuppressive regiments. This transplantation has now been indicated

  8. Liver transplantation in the Nordic countries – An intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982–2013

    Science.gov (United States)

    Fosby, Bjarte; Melum, Espen; Bjøro, Kristian; Bennet, William; Rasmussen, Allan; Andersen, Ina Marie; Castedal, Maria; Olausson, Michael; Wibeck, Christina; Gotlieb, Mette; Gjertsen, Henrik; Toivonen, Leena; Foss, Stein; Makisalo, Heikki; Nordin, Arno; Sanengen, Truls; Bergquist, Annika; Larsson, Marie E.; Soderdahl, Gunnar; Nowak, Greg; Boberg, Kirsten Muri; Isoniemi, Helena; Keiding, Susanne; Foss, Aksel; Line, Pål-Dag; Friman, Styrbjörn; Schrumpf, Erik; Ericzon, Bo-Göran; Höckerstedt, Krister; Karlsen, Tom H.

    2015-01-01

    Abstract Aim and background. The Nordic Liver Transplant Registry (NLTR) accounts for all liver transplants performed in the Nordic countries since the start of the transplant program in 1982. Due to short waiting times, donor liver allocation has been made without considerations of the model of end-stage liver disease (MELD) score. We aimed to summarize key outcome measures and developments for the activity up to December 2013. Materials and methods. The registry is integrated with the operational waiting-list and liver allocation system of Scandiatransplant (www.scandiatransplant.org) and accounted at the end of 2013 for 6019 patients out of whom 5198 were transplanted. Data for recipient and donor characteristics and relevant end-points retransplantation and death are manually curated on an annual basis to allow for statistical analysis and the annual report. Results. Primary sclerosing cholangitis, acute hepatic failure, alcoholic liver disease, primary biliary cirrhosis and hepatocellular carcinoma are the five most frequent diagnoses (accounting for 15.3%, 10.8%, 10.6%, 9.3% and 9.0% of all transplants, respectively). Median waiting time for non-urgent liver transplantation during the last 10-year period was 39 days. Outcome has improved over time, and for patients transplanted during 2004–2013, overall one-, five- and 10-year survival rates were 91%, 80% and 71%, respectively. In an intention-to-treat analysis, corresponding numbers during the same time period were 87%, 75% and 66%, respectively. Conclusion. The liver transplant program in the Nordic countries provides comparable outcomes to programs with a MELD-based donor liver allocation system. Unique features comprise the diagnostic spectrum, waiting times and the availability of an integrated waiting list and transplant registry (NLTR). PMID:25959101

  9. Routine pre-operative focused ultrasonography by anesthesiologists in patients undergoing urgent surgical procedures

    DEFF Research Database (Denmark)

    Bøtker, M T; Vang, M L; Grøfte, T;

    2014-01-01

    with focused ultrasonography in patients undergoing urgent surgical procedures. Methods We performed pre-operative focused cardiopulmonary ultrasonography in patients aged 18 years or above undergoing urgent surgical procedures at pre-defined study days. Known and unexpected cardiopulmonary pathology...... was recorded, and subsequent changes in the anesthesia technique or supportive actions were registered. Results A total of 112 patients scheduled for urgent surgical procedures were included. Their mean age (standard deviation) was 62 (21) years. Of these patients, 24% were American Society....... Unexpected pathology leading to changes in anesthesia technique or supportive actions was only disclosed in a group of patients above the age of 60 years and/or in ASA class ≥ 3. Conclusion Focused cardiopulmonary ultrasonography disclosed unexpected pathology in patients undergoing urgent surgical...

  10. Urgent Care Facilities, care facilities attribute, Published in 2006, Washoe County.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Urgent Care Facilities dataset, was produced all or in part from Published Reports/Deeds information as of 2006. It is described as 'care facilities attribute'....

  11. An urgent need to restrict access to pesticides based on human lethality.

    OpenAIRE

    Matthew Miller; Kavi Bhalla

    2010-01-01

    Matthew Miller and Kavi Bhalla discuss new research findings from Andrew Dawson and colleagues on the human toxicity of pesticides in Sri Lanka, and call for urgent reclassification of agricultural pesticides to help reduce suicides by poisonings.

  12. [Vestibular neuronitis in a teenager with sickle cell disease. Treatment is urgent].

    Science.gov (United States)

    Runel-Belliard, C; Lesprit, E; Quinet, B; Wiener-Vacher, S; Saizou, C; Grimprel, E

    2008-09-01

    Vestibular syndrome is not frequently described in patients with sickle cell disease. We report the case of a teenager with sickle cell disease who had a vestibular syndrome with vertigo that successfully responded to exchange transfusion. We discuss guidelines and review the literature in view of this case report. Sensorineural disorders should be considered as stroke syndromes. They require urgent treatment consisting of exchange transfusion or maintaining optimal hydration associated with blood withdrawal. Treatment of vestibular syndrome in sickle cell disease is urgent.

  13. Outcomes and Role of Urgent Endoscopy in High-Risk Patients With Acute Nonvariceal Gastrointestinal Bleeding.

    Science.gov (United States)

    Cho, Soo-Han; Lee, Yoon-Seon; Kim, Youn-Jung; Sohn, Chang Hwan; Ahn, Shin; Seo, Dong-Woo; Kim, Won Young; Lee, Jae Ho; Lim, Kyoung Soo

    2017-06-19

    We investigated clinical outcomes in high-risk patients with acute nonvariceal upper gastrointestinal bleeding (UGIB), and determined if urgent endoscopy is effective. Consecutive patients with a Glasgow-Blatchford score greater than 7 who underwent endoscopy for acute nonvariceal UGIB at the emergency department from January 1, 2005, to December 31, 2014, were included. Urgent (nonvariceal UGIB. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.

  14. Corneal transplant - discharge

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000243.htm Corneal transplant - discharge To use the sharing features on this page, please enable JavaScript. You had a corneal transplant. Most of the tissue of your cornea (the ...

  15. International Transplant Nurses Society

    Science.gov (United States)

    ... The Mission of ITNS The International Transplant Nurses Society is committed to the promotion of excellence in ... 20-1589538 Copyright © 2006 - 2014 International Transplant Nurses Society (ITNS). No materials, including graphics, may be reused, ...

  16. Fecal microbiota transplant

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007703.htm Fecal microbiota transplant To use the sharing features on this page, please enable JavaScript. Fecal microbiota transplantation (FMT) helps to replace some of the "bad" ...

  17. Watching the Birth of Super Star Clusters

    CERN Document Server

    Turner, J L; Turner, Jean L.; Beck, Sara C.

    2003-01-01

    Subarcsecond infrared and radio observations yield important information about the formation of super star clusters from their surrounding gas. We discuss the general properties of ionized and molecular gas near young, forming SSCs, as illustrated by the prototypical young forming super star cluster nebula in the dwarf galaxy, NGC 5253. This super star cluster appears to have a gravitationally bound nebula. The lack of molecular gas suggests a very high star formation efficiency, consistent with the formation of a large, bound star cluster.

  18. Organ Transplants in Kazakhstan.

    Science.gov (United States)

    Baigenzhin, Abay; Doskaliyev, Zhaksylyk; Tuganbekova, Saltanat; Zharikov, Serik; Altynova, Sholpan; Gaipov, Abduzhappar

    2015-11-01

    The Republic of Kazakhstan is one of the fastest developing countries in the world and has a health care system that is unique in Central Asia. Its organ transplant services are also developing rapidly. We aimed to analyze and briefly report on the current status of organ transplant in the Republic of Kazakhstan. We analyzed organ transplant activities in that country for the period 2012 to 2014. All data were collected from the official database of the National Transplant Coordinating Center of the Republic of Kazakhstan. At the end of 2014, the number of transplant centers had increased to 10, three of which could perform multiorgan transplants; during the same period, the number of deceased-donor organ-donating hospitals increased up to 37. By 2013, the transplant activity rate for all centers had reached 9.22 per million population. During the previous 3 years (2012-2014), there was a 3-fold increase in the number of living donors and an 18-fold increase in the number of kidney transplants. Between 2012 and 2014, the number of living-donor liver transplants increased from 17 to 25, and the number of deceased-donor transplants increased from 3 to 7. During the last 3 years (2012-2014), the number of heart transplants increased to 7 cases. During the last 3 years (2012-2014), Kazakhstan achieved a significant improvement in the organization of its transplant services, and a noticeable upward trend in the system continues.

  19. Cryptococcosis in kidney transplant recipients in a Chinese university hospital and a review of published cases.

    Science.gov (United States)

    Yang, Ya-li; Chen, Min; Gu, Ju-lin; Zhu, Fan-yuan; Xu, Xiao-guang; Zhang, Chao; Chen, Jiang-han; Pan, Wei-hua; Liao, Wan-qing

    2014-09-01

    Cryptococcosis is a severe fungal infection with a high mortality rate among solid-organ transplant recipients. Today, China is among the countries performing the most kidney transplants worldwide, however data on the association of cryptococcosis with kidney transplantation in mainland China remain scarce and fragmented. We retrospectively analyzed cases of culture-confirmed cryptococcosis following kidney transplantation that have occurred at our hospital and reviewed the published cases in China over the last 30 years. Cryptococcosis in kidney transplant recipients was mainly caused by Cryptococcus neoformans var. grubii VNI strains and occurred most frequently in patients aged 41-50 years (37.9%, 11/29). The average time to infection after kidney transplantation was 5.16 ± 3.97 years. The clinical manifestations were found to be diverse, with slight to moderate headache and fever, meningeal irritation, and high cerebrospinal fluid pressure being relatively common. Physicians should be alert to these symptoms among kidney transplant recipients. Cryptococcosis is a serious infection among kidney transplant recipients in mainland China. It has unique characteristics, such as a relatively long time to onset after kidney transplantation, and diverse clinical manifestations. Treatment with intrathecal injection of amphotericin B is considered effective for central nervous system involvement. The findings of this study also highlight the urgent need for multicenter, prospective, and multidisciplinary clinical studies and education on cryptococcosis in kidney transplant recipients in China. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  20. Two-Component Super AKNS Equations and Their Finite-Dimensional Integrable Super Hamiltonian System

    OpenAIRE

    Jing Yu; Jingwei Han

    2014-01-01

    Starting from a matrix Lie superalgebra, two-component super AKNS system is constructed. By making use of monononlinearization technique of Lax pairs, we find that the obtained two-component super AKNS system is a finite-dimensional integrable super Hamiltonian system. And its Lax representation and $r$ -matrix are also given in this paper.

  1. Two-Component Super AKNS Equations and Their Finite-Dimensional Integrable Super Hamiltonian System

    Directory of Open Access Journals (Sweden)

    Jing Yu

    2014-01-01

    Full Text Available Starting from a matrix Lie superalgebra, two-component super AKNS system is constructed. By making use of monononlinearization technique of Lax pairs, we find that the obtained two-component super AKNS system is a finite-dimensional integrable super Hamiltonian system. And its Lax representation and r-matrix are also given in this paper.

  2. Organ transplantation in Bulgaria.

    Science.gov (United States)

    Naumova, Elissaveta; Panchev, Petar; Simeonov, Pencho J; Mihaylova, Anastassia; Penkova, Kalina; Boneva, Petia; Marinova, Daniela; Paskalev, Emil; Simeonov, Petar L; Zlatev, Assen

    2008-12-01

    The transplantation program in Bulgaria started in 1968 with renal transplantations to a child and adult woman. In 1986 the first heart transplantation was performed. To date a total of 10 heart transplants have been performed, including one combined heart/lung. A liver transplantation program was launched in 2005 with a total number of 16 transplantations-7 from living donors and 9 from deceased donors. The highest transplantation activity is registered in the field of renal transplantation. During the period 1980-2006, 462 Bulgarian recipients of kidney were transplanted in Bulgaria. The ratio between transplantations from deceased and living related donors is approximately 1:0.9. Annual transplantation activity varies among the years from 1 to 12 renal transplantations p.m.p./per year. The 1- (80.7% vs. 63.1%), 5- (57.86% vs. 39.0%) and 10-year (42.65% vs. 23.62%) graft survival rates are higher for recipients of living donor kidneys compared to those of deceased donor. In 1983 a National kidney waiting list was established. Currently the number of the registered patients eligible for renal transplantation is 885. The proportion of sensitized patients in the waiting list is 20.45% and 4.34% of them are hyperimmunized. Recently HLAMatchmaker program has been implemented not only for sensitized patients but also for those with rare alleles and haplotypes. Post-transplant immunological monitoring showed a strong association between alloantibody presence and delayed graft function (Chi-square=10.73, P<0.001), acute rejection (Chi-square=14.504, P<0.001), chronic rejection (Chi-square=12.84, P<0.001) and graft loss (Chi-square=20.283, P<0.001). Based on the experience in our transplant center a strategy for improvement of long-term renal graft survival was developed and implemented.

  3. Hepatic artery thrombosis in live liver donor transplantation: how to solve--a case report.

    Science.gov (United States)

    Rodrigues, S; Martins, A; Barroso, E

    2014-01-01

    The decrease in the number of cadaveric donors has proved a limiting factor in the number of liver transplants, leading to the death of many patients on the waiting list. The living donor liver transplantation is an option that allows, in selected cases, increase the number of donors. One of the most serious complications in liver transplantation is hepatic artery thrombosis, in the past considered potentially fatal without urgent re-transplantation. A white male patient, 48 years old, diagnosed with hepatocellular carcinoma in chronic liver failure caused by hepatitis B virus, underwent living donor liver transplantation (right lobe). Doppler echocardiography performed in the immediate postoperative period did not identify arterial flow in the right branch, having been confirmed thrombosis of the right hepatic artery in CT angiography. Urgent re-laparotomy was performed, which consisted of thrombectomy and re-anastomosis of the hepatic artery with segmental splenic artery allograft interposition. The patient started anticoagulation and antiplatelet therapy with acetylsalicylic acid. Serial evaluation with Doppler echocardiography showed hepatic artery patency. At present, the patient is asymptomatic. One of the most devastating complications in liver transplantation, and particularly in living liver donor, is thrombosis of the hepatic artery; thus, early diagnosis and treatment is vital. The rapid intervention for revascularization of the graft avoids irreversible ischemia of the bile ducts and hepatic parenchyma, thus avoiding the need for re-transplantation.

  4. Highlights from Super-Kamiokande

    Science.gov (United States)

    Okumura, Kimihiro

    2016-11-01

    Recent results from Super-Kamiokande experiment are reviewed in this paper; Neutrino mass hierarchy and CP violation in the lepton sector are investigated via νμ → νe oscillation of the atmospheric neutrinos. The event rate, correlation with solar activity, energy spectrum of the solar neutrinos are measured via electron elastic scattering interactions. Neutrino emission from the WIMP annihilation at the center of the Sun are searched in the GeV energy regions. New project, SK-Gd project, to enhance anti-neutrino identification capability, has been approved inside the collaboration group.

  5. Highlights from Super-Kamiokande

    Directory of Open Access Journals (Sweden)

    Okumura Kimihiro

    2016-01-01

    Full Text Available Recent results from Super-Kamiokande experiment are reviewed in this paper; Neutrino mass hierarchy and CP violation in the lepton sector are investigated via νμ → νe oscillation of the atmospheric neutrinos. The event rate, correlation with solar activity, energy spectrum of the solar neutrinos are measured via electron elastic scattering interactions. Neutrino emission from the WIMP annihilation at the center of the Sun are searched in the GeV energy regions. New project, SK-Gd project, to enhance anti-neutrino identification capability, has been approved inside the collaboration group.

  6. Anesthesia for Heart Transplantation.

    Science.gov (United States)

    Ramsingh, Davinder; Harvey, Reed; Runyon, Alec; Benggon, Michael

    2017-09-01

    This article seeks to evaluate current practices in heart transplantation. The goals of this article were to review current practices for heart transplantation and its anesthesia management. The article reviews current demographics and discusses the current criteria for candidacy for heart transplantation. The process for donor and receipt selection is reviewed. This is followed by a review of mechanical circulatory support devices as they pertain to heart transplantation. The preanesthesia and intraoperative considerations are also discussed. Finally, management after transplantation is also reviewed. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Transplante de intestino delgado

    OpenAIRE

    Pécora,Rafael Antonio Arruda; David, André Ibrahim; Lee,André Dong; Galvão,Flávio Henrique; Cruz-Junior,Ruy Jorge; D?Albuquerque, Luiz Augusto Carneiro

    2013-01-01

    INTRODUÇÃO: O transplante de intestino delgado, em razão de sua complexidade, apresentou evolução mais lenta que os demais órgãos sólidos. Diversos avanços permitiram sua aplicação clínica. OBJETIVO: Revisão da evolução do transplante de intestino delgado e seu estado atual. MÉTODO: levantamento bibliográfico nas bases de dados MEDLINE e ScIELO. Os termos usados como descritores foram: intestinal failure, intestinal transplant, small bowel transplant, multivisceral transplant. Foram analisado...

  8. Novel nasogastric tube-related criteria for urgent endoscopy in nonvariceal upper gastrointestinal bleeding.

    Science.gov (United States)

    Iwasaki, Hiroyasu; Shimura, Takaya; Yamada, Tomonori; Aoki, Miho; Nomura, Satoshi; Kusakabe, Atsunori; Kanie, Hiroshi; Ban, Tesshin; Hayashi, Katsumi; Joh, Takashi; Orito, Etsuro

    2013-09-01

    Patients with active upper gastrointestinal bleeding (UGIB) require urgent endoscopy, but appropriate criteria for urgent endoscopy in these patients have not yet been established. The goal of this study is to establish a simple system for the selection of UGIB patients who may benefit from urgent endoscopy. Of the 335 patients who required emergency hospitalization for UGIB from May 2010 to March 2012 at Nagoya Daini Red Cross Hospital, 166 patients who underwent placement of a nasogastric tube (NGT) were retrospectively identified. Active bleeding on the endoscopic image was used as an endpoint that reflected the need for urgent endoscopy. The ratio of the heart rate to the systolic blood pressure (HR/SBP ratio) and aspiration of fresh or dark red fluid from the NGT [NGT(+)] were significant predictors of active bleeding in the univariate analysis [HR/SBP ratio, P=0.016; NGT(+), Pbleeding in the multivariate analysis. Moreover, receiver operating characteristic analysis revealed a setting with HR/SBP ratio>1.4 or NGT(+) to be optimal criteria to predict active bleeding. These criteria were associated with a sensitivity of 64.9% (24/37) and a specificity of 76.7% (99/129) for the prediction of active bleeding; consequently, they are superior to the sensitivity and specificity of previously proposed criteria. A novel and simple criteria system using NGT(+) and HR/SBP is a good predictor of the need for urgent endoscopy in patients with nonvariceal UGIB.

  9. Urgent care medicine and the role of the APP within this specialty.

    Science.gov (United States)

    Memmel, Jessica; Spalsbury, Marcy

    2017-05-01

    The field of urgent care medicine offers an additional medical pathway for patients who have immediate, but non-life-threatening, medical concerns. Urgent care medicine offers a more varied set of resources and services than a physician office setting, with more flexible hours. This gives patients an opportunity to not have to go to the emergency department for non-emergent care. As a newer specialty within the medical field, certain roles of healthcare providers other than physicians are becoming established, including the advanced practice provider (APP). An APP is a nurse practitioner or a physician assistant, who is licensed to treat under the supervision of a physician. Nurse practitioners' (NP) and physician assistants' (PA) role in urgent care is often seen as an effective, lower cost option to manage common acute minor illnesses seen in the community. Benefits to utilizing APPs in urgent care include decreasing costs to both the patient and health system, enhancing the physician's ability to see more patients, and decreasing wait times, all while continuing to maintain high standards of care. The goal of the authors within this publication is to discuss urgent care as a specialty and further explore the role of advanced practice providers within this setting. Copyright © 2017 Elsevier GmbH. All rights reserved.

  10. Infection Prevention in Transplantation.

    Science.gov (United States)

    Pergam, Steven A

    2016-01-01

    The number of patients undergoing hematopoietic cell and solid organ transplantation are increasing every year, as are the number of centers both transplanting and caring for these patients. Improvements in transplant procedures, immunosuppressive regimens, and prevention of transplant-associated complications have led to marked improvements in survival in both populations. Infections remain one of the most important sources of excess morbidity and mortality in transplant, and therefore, infection prevention strategies are a critical element for avoiding these complications in centers caring for high-risk patients. This manuscript aims to provide an update of recent data on prevention of major healthcare-associated infections unique to transplantation, reviews the emergence of antimicrobial resistant infections, and discusses updated strategies to both identify and prevent transmission of these pathogens in transplant recipients.

  11. Optical trapping with Super-Gaussian beams

    CSIR Research Space (South Africa)

    McLaren, M

    2013-04-01

    Full Text Available We outline the possibility of optical trapping and tweezing with Super-Gaussian beam profiles. We show that the trapping strength can be tuned continuously by adjusting the order of a Super-Gaussian beam, approaching that of a perfect Gaussian...

  12. Tetrahedral Units: For Dodecahedral Super-Structures

    CERN Document Server

    Ortiz, Y; Liebman, J F

    2016-01-01

    Different novel organic-chemical possibilities for tetrahedral building units are considered, with attention to their utility in constructing different super-structures. As a representative construction we consider the use of sets of 20 such identical tetrahedral units to form a super-dodecahedron.

  13. dbSUPER: a database of super-enhancers in mouse and human genome.

    Science.gov (United States)

    Khan, Aziz; Zhang, Xuegong

    2016-01-04

    Super-enhancers are clusters of transcriptional enhancers that drive cell-type-specific gene expression and are crucial to cell identity. Many disease-associated sequence variations are enriched in super-enhancer regions of disease-relevant cell types. Thus, super-enhancers can be used as potential biomarkers for disease diagnosis and therapeutics. Current studies have identified super-enhancers in more than 100 cell types and demonstrated their functional importance. However, a centralized resource to integrate all these findings is not currently available. We developed dbSUPER (http://bioinfo.au.tsinghua.edu.cn/dbsuper/), the first integrated and interactive database of super-enhancers, with the primary goal of providing a resource for assistance in further studies related to transcriptional control of cell identity and disease. dbSUPER provides a responsive and user-friendly web interface to facilitate efficient and comprehensive search and browsing. The data can be easily sent to Galaxy instances, GREAT and Cistrome web-servers for downstream analysis, and can also be visualized in the UCSC genome browser where custom tracks can be added automatically. The data can be downloaded and exported in variety of formats. Furthermore, dbSUPER lists genes associated with super-enhancers and also links to external databases such as GeneCards, UniProt and Entrez. dbSUPER also provides an overlap analysis tool to annotate user-defined regions. We believe dbSUPER is a valuable resource for the biology and genetic research communities.

  14. Success of Urgent-Start Peritoneal Dialysis in a Large Canadian Renal Program.

    Science.gov (United States)

    Alkatheeri, Ali M A; Blake, Peter G; Gray, Daryl; Jain, Arsh K

    2016-01-01

    ♦ Many patients start renal replacement therapy urgently on in-center hemodialysis via a central venous catheter, which is considered suboptimal. An alternative approach to manage these patients is to start them on peritoneal dialysis (PD). In this report, we describe the first reported Canadian experience with an urgent-start PD program. Additionally we reviewed the literature in this area. ♦ In this prospective observational study, we report on our experience in a single academic center. This program started in July 2010. We included patients who initiated PD urgently, that is within 2 weeks of catheter insertion. We followed all incident PD patients until October 2013 for mechanical and infectious complications. Peritoneal dialysis catheters were inserted either percutaneously or laparoscopically and dialysis was initiated in either an inpatient or outpatient setting. ♦ Thirty patients were started on urgent PD during our study period. Follow-up ranged from 28 to 1,050 days. Twenty insertions (66.7%) were done percutaneously and 10 (33.3%) were laparoscopic. Dialysis was initiated within 2 weeks (range: 0-13 days, median = 6 days). Twenty-four patients (80%) started PD in an outpatient setting and 6 patients (20%) required immediate inpatient PD start. Three patients (10%) developed a minor peri-catheter leak during the first week of training that was managed conservatively. There were no episodes of peritonitis or exit-site/tunnel infection during the first 4 weeks post-insertion. Four patients (13.3%) from the percutaneous insertion group and 2 patients (6.7%) from laparoscopic insertions developed catheter dysfunction due to migration, which was managed by repositioning, without need for catheter replacement or modality switch. ♦ Our results are consistent with other studies in this area and demonstrate that urgent-start PD is an acceptable and safe alternative to hemodialysis in patients who need to start dialysis urgently without established

  15. Ending Aging in Super Glassy Polymer Membranes

    Energy Technology Data Exchange (ETDEWEB)

    Lau, CH; Nguyen, PT; Hill, MR; Thornton, AW; Konstas, K; Doherty, CM; Mulder, RJ; Bourgeois, L; Liu, ACY; Sprouster, DJ; Sullivan, JP; Bastow, TJ; Hill, AJ; Gin, DL; Noble, RD

    2014-04-16

    Aging in super glassy polymers such as poly(trimethylsilylpropyne) (PTMSP), poly(4-methyl-2-pentyne) (PMP), and polymers with intrinsic microporosity (PIM-1) reduces gas permeabilities and limits their application as gas-separation membranes. While super glassy polymers are initially very porous, and ultra-permeable, they quickly pack into a denser phase becoming less porous and permeable. This age-old problem has been solved by adding an ultraporous additive that maintains the low density, porous, initial stage of super glassy polymers through absorbing a portion of the polymer chains within its pores thereby holding the chains in their open position. This result is the first time that aging in super glassy polymers is inhibited whilst maintaining enhanced CO2 permeability for one year and improving CO2/N-2 selectivity. This approach could allow super glassy polymers to be revisited for commercial application in gas separations.

  16. Telejornalismo dramático e a vida cotidiana: estudo de caos do programa Brasil Urgente

    OpenAIRE

    Ligia Campos de Cerqueira Lana

    2007-01-01

    O propósito desta pesquisa é apreender as relações entre a televisão e a vida cotidiana por meio de um estudo de caso do programa Brasil Urgente. Os sentidos sobre o dia-a-dia sãoconstruídos e transformados pelo telejornalismo dramático. Ao resgatar práticas compartilhadas da sociedade, Brasil Urgente dialoga com a cultura criando e recriando o cotidiano das cidades, associado à violência e também a contextos mais amplos. O trabalho apresenta o panorama histórico do surgimento dos telejornais...

  17. Effect of Mouth Cancer Awareness Week on urgent suspected head and neck cancer referrals.

    Science.gov (United States)

    Rafiq, Raheela; Brocklehurst, Paul; Rogers, Simon N

    2013-10-01

    The purpose of this study was to find out whether Mouth Cancer Awareness Week and associated activities made any difference to the number of urgent or two-week urgent referrals to the oral and maxillofacial department at University Hospital, Aintree, whether they were appropriate, and the number of patients who were found to have cancer. A prospective audit over six months before, during, and after the awareness week showed a rise in the number of referrals over time, with the highest number in February. Of the 120 patients evaluated, cancer was confirmed in 13 (11%).

  18. The urgent need for universities to comprehensively address global climate change across disciplines and programs.

    Science.gov (United States)

    Lemons, John

    2011-09-01

    I review the status of scientific, political, and moral problems of global climate change (GCC) and, based on lessons from environmental and sustainability programs in universities, demonstrate that universities have had a lethargic response to urgent needs to mitigate the problems. I explore reasons for the response, and conclude that there is an urgent need for comprehensive and wide-ranging change in universities to help mitigate GCC. My discussion is focused on those within universities as well as those in environmental professions regardless of their areas of specialization.

  19. Future of transplantation medicine.

    Science.gov (United States)

    Rowiński, Wojciech

    2007-01-01

    Organ transplantation has become very successful method of treatment of end stage organ disease. However the waiting lists of patients aiming such treatment are exponentially growing due to insufficient organ supply. Prognosis of the future for transplantation medicine is truly difficult. Prospects from past years, that "soon induction of tolerance will become possible"(1975), wide xenogenic transplant utilization (in 2000), fetal brain cell transplantation to treat some neurologic disease and transplantation of isolated cells instead of whole organs (1998) proved wrong. The research in the nearest future will be focused on tolerance induction, inhibition of alloreaction in blood-group discordant transplants (in immunized patients) and xenografts. In parallel, studies on hybrid and totally artificial, implantable devices (artificial pancreas and liver) will be carried on. 21st century will belong to regeneration medicine, with therapeutic applications of stem cells.

  20. Cuba's kidney transplantation program.

    Science.gov (United States)

    Mármol, Alexander; Pérez, Alexis; Pérez de Prado, Juan C; Fernández-Vega, Silvia; Gutiérrez, Francisco; Arce, Sergio

    2010-10-01

    The first kidney transplant in Cuba was performed on 24 February 1970, using a cadaveric donor. In 1979, living donor kidney transplantation began between first-degree relatives. A total of 2775 patients are enrolled in renal replacement therapy in 47 hospitals across the country, 1440 of whom are awaiting kidney transplantation. Organs for the kidney program are procured in 63 accredited hospitals equipped for multidisciplinary management of brain death. Accordingly, over 90% of transplanted kidneys are from cadaveric donors. Identification of potential recipients is carried out through a national, computerized program that affords all patients the same opportunity regardless of distance from a transplant center, and selection of the most suitable candidate is based primarily on HLA compatibility. KEYWORDS Chronic renal failure, kidney transplantation.

  1. Transplantation psychoneuroimmunology: building hypotheses.

    Science.gov (United States)

    Klapheke, M M

    2000-06-01

    The research findings of psychoneuroimmunology have not yet been fully applied to the field of transplantation psychiatry. Though much study has been devoted to the impact of psychiatric disease on the immunosuppressed state and disease progression in HIV-related illness, little has yet been written on the immunology implications of psychiatric disturbances in the immunosuppressed post-transplant patient. Utilizing Medline literature searches to review relevant research data in psychoneuroimmunology and transplantation immunology, the author formulates and examines four transplantation psychoneuroimmunology hypotheses involving the potential impact of depression on post-transplant organ rejection, cancer, coronary artery disease, and infections. The author concludes that though major questions remain, it appears reasonable to include the impact of depression, and possibly other psychological states, among factors that may affect the net state of immunosuppression in transplant patients.

  2. 75 FR 67013 - Unexpected Urgent Refugee and Migration Needs Resulting from Violence in Kyrgyzstan

    Science.gov (United States)

    2010-11-01

    ... HOUSE, WASHINGTON, August 26, 2010 [FR Doc. 2010-27672 Filed 10-29-10; 8:45 am] Billing code 4710-10-P ... Documents#0;#0; ] Presidential Determination No. 2011-12 of August 26, 2010 Unexpected Urgent Refugee and...) of the Migration and Refugee Assistance Act of 1962 (the ``Act''), as amended (22 U.S.C....

  3. 75 FR 67015 - Unexpected Urgent Refugee And Migration Needs Resulting From Flooding InPakistan

    Science.gov (United States)

    2010-11-01

    ....) THE WHITE HOUSE, WASHINGTON, September 3, 2010 [FR Doc. 2010-27673 Filed 10-29-10; 8:45 am] Billing... Documents#0;#0; ] Presidential Determination No. 2011-14 of September 3, 2010 Unexpected Urgent Refugee And...) of the Migration and Refugee Assistance Act of 1962 (the ``Act''), as amended (22 U.S.C....

  4. Urgent resection of bleeding congenital mesenchymal chest wall hamartoma in an infant

    Directory of Open Access Journals (Sweden)

    Bieda, Jan-Christoph

    2013-10-01

    Full Text Available We report a case with prenatally diagnosed large cystic-solid mesenchymal chest wall hamartoma. An attempt of conservative management was made however repeated intralesional hemorrhage led to enlargement and severe anemia which required urgent resection at the age of 8 weeks. The infant had an unimpaired development over a follow-up of 4 years.

  5. 76 FR 53295 - Unexpected Urgent Refugee and Migration Needs Related to the Horn of Africa

    Science.gov (United States)

    2011-08-25

    ... Urgent Refugee and Migration Needs Related to the Horn of Africa Presidential Determination No. 2011-13... Africa Memorandum for the Secretary of State By the authority vested in me as President by the... humanitarian crisis in the Horn of Africa. You are authorized and directed to publish this memorandum in...

  6. The intracerebral haemorrhage associated to oral anticoagulant therapy: the practical management of urgent reversal therapy

    Directory of Open Access Journals (Sweden)

    Luca Masotti

    2011-04-01

    Full Text Available Intracerebral haemorrhage (ICH represents the most feared complication of therapy with vitamin K antagonists (VKA, so-called oral anticoagulant therapy (OAT. This is a real emergency in clinical practice, being burdened by high mortality, morbidity and residual functional disability. In recent years, there have been widespread indications for the correct management of VKA associated ICH. The urgent OAT reversal represents the cornerstone of VKA associated ICH therapy. The knowledge of these guidelines is of fundamental importance in clinical practice. The urgent OAT reversal could stop the hematoma enlargement which is considered one of the main risk factor of poor outcome in this clinical setting. The aim of urgent OAT reversal is bringing the INR (International Normalized Ratio to values ≤ 1.4. It is possible by using prothrombin complex concentrate (PCC, fresh frozen plasma (FFP, recombinant activated factor VII (raFVII together with vitamin K1 intravenous infusion. In this article the Authors review the practical management of urgent OAT reversal in patients suffering for VKA related ICH.

  7. Urgent carotid endarterectomy in patients with acute neurological ischemic events within six hours after symptoms onset.

    Science.gov (United States)

    Gajin, P; Radak, Dj; Tanaskovic, S; Babic, S; Nenezic, D

    2014-06-01

    To analyze the outcome of urgent carotid endarterectomy (CEA) performed within less than six hours in patients with crescendo transient ischemic attack (TIA) and stroke in progression. From January 1998 to December 2008, 58 urgent CEAs were done for acute neurological ischemic events--46 patients with crescendo TIA and 12 patients with stroke in progression. Brain computed tomography (CT) was done prior and after the surgery. Disability level was assessed prior to and after urgent CEA using modified Rankin scale. Median follow-up was 42.1 ± 16.6 months. In the early postoperative period stroke rate was 0% for the patients in crescendo TIA group while in patients with stroke in progression group 3 patients (25%) had positive postoperative brain CT, yet neurological status significantly improved. Mid-term stroke rate was 2.2% in crescendo TIA group and 8.3% in stroke in progression group. In the early postoperative period there were no lethal outcomes, mid-term mortality was 8.3% in stroke in progression while in crescendo TIA group lethal outcomes were not observed. In conclusion, based on our results urgent CEA is a safe and effective treatment option for patients with crescendo TIA and stroke in progression with acceptable rate of postoperative complications.

  8. If climate action becomes urgent: The importance of response times for various climate strategies

    NARCIS (Netherlands)

    van Vuuren, D.P.; Stehfest, E.

    2013-01-01

    Most deliberations on climate policy are based on a mitigation response that assumes a gradually increasing reduction over time. However, situations may occur where a more urgent response is needed. A key question for climate policy in general, but even more in the case a rapid response is needed, i

  9. Urgent resection of bleeding congenital mesenchymal chest wall hamartoma in an infant.

    Science.gov (United States)

    Bieda, Jan-Christoph; Tröbs, Ralf-Bodo; Roll, Claudia; Wunsch, Rainer; Neid, Matthias

    2013-01-01

    We report a case with prenatally diagnosed large cystic-solid mesenchymal chest wall hamartoma. An attempt of conservative management was made however repeated intralesional hemorrhage led to enlargement and severe anemia which required urgent resection at the age of 8 weeks. The infant had an unimpaired development over a follow-up of 4 years.

  10. Pediatric heart transplantation

    OpenAIRE

    Schweiger, Martin; Stiasny, Brian; Dave, Hitendu; Cavigelli-Brunner, Anna; Balmer, Christian; Kretschmar, Oliver; Bürki, Christoph; Klauwer, Dietrich; Hübler, Michael

    2015-01-01

    Pediatric heart transplantation (pHTx) represents a small (14%) but very important and particular part in the field of cardiac transplantation. This treatment has lifelong impact on children. To achieve the best short and especially long-term survival with adequate quality of life, which is of crucial importance for this young patient population, one has to realize and understand the differences with adult HTx. Indication for transplantation, waitlist management including ABO incompatible (AB...

  11. Split liver transplantation.

    Science.gov (United States)

    Yersiz, H; Cameron, A M; Carmody, I; Zimmerman, M A; Kelly, B S; Ghobrial, R M; Farmer, D G; Busuttil, R W

    2006-03-01

    Seventy-five thousand Americans develop organ failure each year. Fifteen percent of those on the list for transplantation die while waiting. Several possible mechanisms to expand the organ pool are being pursued including the use of extended criteria donors, living donation, and split deceased donor transplants. Cadaveric organ splitting results from improved understanding of the surgical anatomy of the liver derived from Couinaud. Early efforts focused on reduced-liver transplantation (RLT) reported by both Bismuth and Broelsch in the mid-1980s. These techniques were soon modified to create both a left lateral segment graft appropriate for a pediatric recipient and a right trisegment for an appropriately sized adult. Techniques of split liver transplantation (SLT) were also modified to create living donor liver transplantation. Pichlmayr and Bismuth reported successful split liver transplantation in 1989 and Emond reported a larger series of nine split procedures in 1990. Broelsch and Busuttil described a technical modification in which the split was performed in situ at the donor institution with surgical division completed in the heart beating cadaveric donor. In situ splitting reduces cold ischemia, simplifies identification of biliary and vascular structures, and reduces reperfusion hemorrhage. However, in situ splits require specialized skills, prolonged operating room time, and increased logistical coordination at the donor institution. At UCLA over 120 in situ splits have been performed and this technique is the default when an optimal donor is available. Split liver transplantation now accounts for 10% of adult transplantations at UCLA and 40% of pediatric transplantations.

  12. [Heart transplantation and infection].

    Science.gov (United States)

    Ozábalová, Eva; Krejčí, Jan; Hude, Petr; Godava, Julius; Honek, Tomáš; Špinarová, Lenka; Pavlík, Petr; Bedáňová, Helena; Němec, Petr

    2017-01-01

    Heart transplantation (HTx) is a method of treatment for patients with end-stage heart failure with severe symptoms despite complex therapy. Post-transplant difficulties include acute rejection and infectious complications, which are the most common reason of morbidity and mortality in the first year after heart transplant. It requires the patient to remain on immunosuppressive medication to avoid the possibility of graft rejection. Therefore the range of infection is much larger. The diagnosis and treatment of viral, bacterial and fungal infections is often difficult.Key words: heart transplantation - immunosuppression - infection.

  13. Extraordinary radiation super-sensitivity accompanying with sorafenib combination therapy: what lies beneath?

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ja Young; Lee, Ju Hye; Yoon, Han Bin; Lee, Ho Jeong; Jeon, Ho Sang; Nam, Ji Ho [Dept. of Radiation Oncology, Pusan National University Yangsan Hospital, Yangsan (Korea, Republic of)

    2017-06-15

    Primary liver tumor, especially hepatocellular carcinoma (HCC), is a common cause of cancer death worldwide. The incidence is generally higher in Asian countries than in western countries. Carcinogenesis of HCC is often associated with hepatitis viral infections. Current standard treatment of HCC is surgical resection or transplantation in patients with early stage disease. However, the patient with advanced stage disease, surgical resection is often limited. Sorafenib or other treatment modalities are not so effective as well. We report a case of unusual radiation super-sensitivity in advanced stage HCC, and review the literature.

  14. Super-resolution image reconstruction methods applied to GFE-referenced navigation system

    Science.gov (United States)

    Yan, Lei; Lin, Yi; Tong, Qingxi

    2007-11-01

    The problem about reference grid data's overlarge spacing, which makes deviated estimation of un-surveyed points and poor accuracy of correlation positioning, has been embarrassing Geophysical Fields of the Earth (GFE) referenced navigation research. The super-resolution images reconstruction methods in remote sensing field give some inspiration, and its brief method, Maximum A-Posterior (MAP) based on Bayesian theory, is transplanted on grid data. The proposed algorithm named MAP-G can implement interpolation of reference data field by reflecting whole distribution trend. Comparison with traditional interpolation algorithms and simulation experiments on underwater terrain/gravity-aided navigation platform, indicate that MAP-G algorithm can effectively improve navigation's performance.

  15. Urgent-Start Peritoneal Dialysis and Hemodialysis in ESRD Patients: Complications and Outcomes.

    Science.gov (United States)

    Jin, Haijiao; Fang, Wei; Zhu, Mingli; Yu, Zanzhe; Fang, Yan; Yan, Hao; Zhang, Minfang; Wang, Qin; Che, Xiajing; Xie, Yuanyuan; Huang, Jiaying; Hu, Chunhua; Zhang, Haifen; Mou, Shan; Ni, Zhaohui

    2016-01-01

    Several studies have suggested that urgent-start peritoneal dialysis (PD) is a feasible alternative to hemodialysis (HD) in patients with end-stage renal disease (ESRD), but the impact of the dialysis modality on outcome, especially on short-term complications, in urgent-start dialysis has not been directly evaluated. The aim of the current study was to compare the complications and outcomes of PD and HD in urgent-start dialysis ESRD patients. In this retrospective study, ESRD patients who initiated dialysis urgently without a pre-established functional vascular access or PD catheter at a single center from January 2013 to December 2014 were included. Patients were grouped according to their dialysis modality (PD and HD). Each patient was followed for at least 30 days after catheter insertion (until January 2016). Dialysis-related complications and patient survival were compared between the two groups. Our study enrolled 178 patients (56.2% male), of whom 96 and 82 patients were in the PD and HD groups, respectively. Compared with HD patients, PD patients had more cardiovascular disease, less heart failure, higher levels of serum potassium, hemoglobin, serum albumin, serum pre-albumin, and lower levels of brain natriuretic peptide. There were no significant differences in gender, age, use of steroids, early referral to a nephrologist, prevalence of primary renal diseases, prevalence of co-morbidities, and other laboratory characteristics between the groups. The incidence of dialysis-related complications during the first 30 days was significantly higher in HD than PD patients. HD patients had a significantly higher probability of bacteremia compared to PD patients. HD was an independent predictor of short-term (30-day) dialysis-related complications. There was no significant difference between PD and HD patients with respect to patient survival rate. In an experienced center, PD is a safe and feasible dialysis alternative to HD for ESRD patients with an urgent need

  16. SuperB Progress Report for Physics

    Energy Technology Data Exchange (ETDEWEB)

    O' Leary, B.; /Aachen, Tech. Hochsch.; Matias, J.; Ramon, M.; /Barcelona, IFAE; Pous, E.; /Barcelona U.; De Fazio, F.; Palano, A.; /INFN, Bari; Eigen, G.; /Bergen U.; Asgeirsson, D.; /British Columbia U.; Cheng, C.H.; Chivukula, A.; Echenard, B.; Hitlin, D.G.; Porter, F.; Rakitin, A.; /Caltech; Heinemeyer, S.; /Cantabria Inst. of Phys.; McElrath, B.; /CERN; Andreassen, R.; Meadows, B.; Sokoloff, M.; /Cincinnati U.; Blanke, M.; /Cornell U., Phys. Dept.; Lesiak, T.; /Cracow, INP /DESY /Zurich, ETH /INFN, Ferrara /Frascati /INFN, Genoa /Glasgow U. /Indiana U. /Mainz U., Inst. Phys. /Karlsruhe, Inst. Technol. /KEK, Tsukuba /LBL, Berkeley /UC, Berkeley /Lisbon, IST /Ljubljana U. /Madrid, Autonoma U. /Maryland U. /MIT /INFN, Milan /McGill U. /Munich, Tech. U. /Notre Dame U. /PNL, Richland /INFN, Padua /Paris U., VI-VII /Orsay, LAL /Orsay, LPT /INFN, Pavia /INFN, Perugia /INFN, Pisa /Queen Mary, U. of London /Regensburg U. /Republica U., Montevideo /Frascati /INFN, Rome /INFN, Rome /INFN, Rome /Rutherford /Sassari U. /Siegen U. /SLAC /Southern Methodist U. /Tel Aviv U. /Tohoku U. /INFN, Turin /INFN, Trieste /Uppsala U. /Valencia U., IFIC /Victoria U. /Wayne State U. /Wisconsin U., Madison

    2012-02-14

    SuperB is a high luminosity e{sup +}e{sup -} collider that will be able to indirectly probe new physics at energy scales far beyond the reach of any man made accelerator planned or in existence. Just as detailed understanding of the Standard Model of particle physics was developed from stringent constraints imposed by flavour changing processes between quarks, the detailed structure of any new physics is severely constrained by flavour processes. In order to elucidate this structure it is necessary to perform a number of complementary studies of a set of golden channels. With these measurements in hand, the pattern of deviations from the Standard Model behavior can be used as a test of the structure of new physics. If new physics is found at the LHC, then the many golden measurements from SuperB will help decode the subtle nature of the new physics. However if no new particles are found at the LHC, SuperB will be able to search for new physics at energy scales up to 10-100 TeV. In either scenario, flavour physics measurements that can be made at SuperB play a pivotal role in understanding the nature of physics beyond the Standard Model. Examples for using the interplay between measurements to discriminate New Physics models are discussed in this document. SuperB is a Super Flavour Factory, in addition to studying large samples of B{sub u,d,s}, D and {tau} decays, SuperB has a broad physics programme that includes spectroscopy both in terms of the Standard Model and exotica, and precision measurements of sin{sup 2} {theta}{sub W}. In addition to performing CP violation measurements at the {Upsilon}(4S) and {phi}(3770), SuperB will test CPT in these systems, and lepton universality in a number of different processes. The multitude of rare decay measurements possible at SuperB can be used to constrain scenarios of physics beyond the Standard Model. In terms of other precision tests of the Standard Model, this experiment will be able to perform precision over

  17. The superB silicon vertex tracker

    Energy Technology Data Exchange (ETDEWEB)

    Rizzo, G., E-mail: giuliana.rizzo@pi.infn.i [INFN-Pisa and Universita di Pisa (Italy); Avanzini, C.; Batignani, G.; Bettarini, S.; Bosi, F.; Calderini, G.; Ceccanti, M.; Cenci, R.; Cervelli, A.; Crescioli, F.; Dell' Orso, M.; Forti, F.; Giannetti, P.; Giorgi, M.A. [INFN-Pisa and Universita di Pisa (Italy); Lusiani, A. [Scuola Normale Superiore and INFN-Pisa (Italy); Gregucci, S.; Mammini, P.; Marchiori, G.; Massa, M.; Morsani, F. [INFN-Pisa and Universita di Pisa (Italy)

    2010-05-21

    The SuperB asymmetric e{sup +}-e{sup -} collider has been designed to deliver a luminosity greater than 10{sup 36}cm{sup -2}s{sup -1} with moderate beam currents. Comparing to current B-Factories, the reduced center of mass boost of the SuperB machine requires improved vertex resolution to allow precision measurements sensitive to New Physics. We present the conceptual design of the silicon vertex tracker (SVT) for the SuperB detector with the present status of the R and D on the different options under study for its innermost Layer0.

  18. N=2 Super - $W_{3}$ Algebra and N=2 Super Boussinesq Equations

    CERN Document Server

    Ivanov, E; Malik, R P

    1995-01-01

    We study classical $N=2$ super-$W_3$ algebra and its interplay with $N=2$ supersymmetric extensions of the Boussinesq equation in the framework of the nonlinear realization method and the inverse Higgs - covariant reduction approach. These techniques have been previously applied by us in the bosonic $W_3$ case to give a new geometric interpretation of the Boussinesq hierarchy. Here we deduce the most general $N=2$ super Boussinesq equation and two kinds of the modified $N=2$ super Boussinesq equations, as well as the super Miura maps relating these systems to each other, by applying the covariant reduction to certain coset manifolds of linear $N=2$ super-$W_3^{\\infty}$ symmetry associated with $N=2$ super-$W_3$. We discuss the integrability properties of the equations obtained and their correspondence with the formulation based on the notion of the second hamiltonian structure.

  19. Bioethics of organ transplantation.

    Science.gov (United States)

    Caplan, Arthur

    2014-03-01

    As the ability to transplant organs and tissues has grown, the demand for these procedures has increased as well--to the point at which it far exceeds the available supply creating the core ethical challenge for transplantation--rationing. The gap between supply and demand, although large, is worse than it appears to be. There are two key steps to gaining access to a transplant. First, one must gain access to a transplant center. Then, those waiting need to be selected for a transplant. Many potential recipients do not get admitted to a program. They are deemed too old, not of the right nationality, not appropriate for transplant as a result of severe mental impairment, criminal history, drug abuse, or simply because they do not have access to a competent primary care physician who can refer them to a transplant program. There are also financial obstacles to access to transplant waiting lists in the United States and other nations. In many poor nations, those needing transplants simply die because there is no capacity or a very limited capacity to perform transplants. Although the demand for organs now exceeds the supply, resulting in rationing, the size of waiting lists would quickly expand were there to suddenly be an equally large expansion in the number of organs available for transplantation. Still, even with the reality of unavoidable rationing, saving more lives by increasing organ supply is a moral good. Current public policies for obtaining organs from cadavers are not adequate in that they do not produce the number of organs that public polls of persons in the United States indicate people are willing to donate.

  20. Transplantation activities in Iran.

    Science.gov (United States)

    Broumand, Behrooz

    2005-06-01

    Iran is a tropical country with a land area of 1,648,000 square kilometers and a population of 68,100,000. Iran has a recorded history that dates back 2553 years. Its earliest medical school was Pasargad. Jondi Chapour University was founded 1753 years ago during the Sassanid dynasty as a center for higher education in medicine, philosophy, and pharmacology. Indeed, the idea of xenotransplantation dates back to days of Achaemenidae (Achaemenian dynasty), as evidenced by engravings of many mythologic chimeras still present in Persepolis. Avicenna (980-1037 AD), the great Iranian physician, performed the first nerve repair. Transplantation progress in Iran follows roughly the same pattern as that of the rest of the world, with some 10-20 years' delay. Modern organ transplantation dates back to 1935, when the first cornea transplant was performed at Farabi Hospital in Tehran, Iran. The first living-related kidney transplantation performed at Shiraz University Hospital dates back to 1968. The first bone marrow transplant was performed at Dr. Shariaati's Hospital in Tehran. The first heart transplant was performed 1993 in Tabriz, Iran. The first liver transplant was performed in 1993 in Shiraz. The first lung transplant was performed in 2001, and the first heart and lung transplants were performed in 2002, both at Tehran. In late 1985, the renal transplantation program was officially started in a major university hospital in Tehran and was poised to carry out 2 to 4 transplantations each week. Soon, another large center initiated a similar program. Both of these centers accepted surgical, medical, and nursing teams from other academic medical centers for training in kidney transplantation. Since 2002, Iran has grown to include 23 active renal, 68 cornea, 2 liver, 4 heart, 2 lung, and 2 bone marrow transplantation centers in different cities. In June 2000, the Organ Transplantation Brain Death Act was approved by the Parliament, followed by the establishment of the

  1. Repeat-PPM Super-Symbol Synchronization

    Science.gov (United States)

    Connelly, J.

    2016-11-01

    To attain a wider range of data rates in pulse position modulation (PPM) schemes with constrained pulse durations, the sender can repeat a PPM symbol multiple times, forming a super-symbol. In addition to the slot and symbol synchronization typically required for PPM, the receiver must also properly align the noisy super-symbols. We present a low-complexity approximation of the maximum-likelihood method for performing super-symbol synchronization without use of synchronization sequences. We provide simulation results demonstrating performance advantage when PPM symbols are spread by a pseudo-noise sequence, as opposed to simply repeating. Additionally, the results suggest that this super-symbol synchronization technique requires signal levels below those required for reliable communication. This validates that the PPM spreading approach proposed to CCSDS can work properly as part of the overall scheme.

  2. Axial Super-resolution Evanescent Wave Tomography

    CERN Document Server

    Pendharker, Sarang; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-01-01

    Optical tomographic reconstruction of a 3D nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography (AxSET) method that enables the use of regular evanescent wave microscopes like Total Internal Reflection Fluorescence Microscope (TIRF) beyond surface imaging, and achieve tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of three-dimensional fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by 1D (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axi...

  3. [Uterus transplantation. Current situation].

    Science.gov (United States)

    Gauthier, T; Piver, P; Mesnard, C; Marquet, P; Pichon, N; Guillaudeau, A; Drouet, M; Gardet, E; Laskar, M; Essig, M; Aubard, Y

    2012-11-01

    Except adoption, absolute uterine factor infertility lacks solution in case of motherhood desire. Gestational surrogacy is still not approved in France. Over the last decade, uterus transplantation experimentation made advances. Data from animal research, progress in immunosuppressive treatment and knowledge about pregnancy after transplantation provide a scenario in which a human allotransplantation project can become reality.

  4. Mirror-enhanced super-resolution microscopy

    OpenAIRE

    2016-01-01

    Axial excitation confinement beyond the diffraction limit is crucial to the development of next-generation, super-resolution microscopy. STimulated Emission Depletion (STED) nanoscopy offers lateral super-resolution using a donut-beam depletion, but its axial resolution is still over 500 nm. Total internal reflection fluorescence microscopy is widely used for single-molecule localization, but its ability to detect molecules is limited to within the evanescent field of ~ 100 nm from the cell a...

  5. [Challenges in renal transplantation].

    Science.gov (United States)

    Thuret, R; Kleinclauss, F; Terrier, N; Karam, G; Timsit, M O

    2016-11-01

    To describe kidney transplantation surgical techniques and to propose strategies in high-risk recipients. Relevant publications were identified through Medline (http://www.ncbi.nlm.nih.gov/) and Embase (http://www.embase.com/) database using the following keywords, alone or in association, "renal transplantation; peripheral arterial disease; obesity; third and fourth transplantation; robotic-assisted kidney transplant; anticoagulant therapy; dual kidney transplant". Articles were selected according to methods, language of publication and relevance. The reference lists were used to identify additional historical studies of interest. Both prospective and retrospective series, in French and English, as well as review articles and case-reports were selected. A total of 1949 articles were analyzed for arterial disease and anticoagulant therapy, 1083 for obesity, 663 for dual kidney transplants, 458 for third and subsequent procedures and 84 for robotic-assisted kidney transplantation. After careful selection, 304 publications were eligible for our review. Surgical assessment of future recipients is a pivotal step to anticipate technical difficulties, to interrupt clopidogrel or direct oral anticoagulants and to propose a revascularization procedure when necessary. Lack of data regarding obese recipients does not allow us to conclude about best surgical care or optimal timing but suggest that an early global management of obesity in chronic kidney disease patients is mandatory to improve access to a successful transplantation. In neurologic bladder and congenital anomalies, urodynamics and bladder function must be assessed prior to the onset of oliguria to intend an early treatment. Urinary diversion may be performed prior to or after transplantation with similar survival outcome and comparable rates of infections. Because of a rigorous selection of donors, the French dual kidney transplant program provides satisfactory outcomes, but fails in convincing surgical

  6. Brain death and organ transplant legislation:analysis of 969 respondents by classroom questionnaire

    Institute of Scientific and Technical Information of China (English)

    Ru-Liang Song; Xiao-Hua Cui; Zhan Gao; Shao-Lin Deng; You-Ping Li

    2009-01-01

    BACKGROUND: China has the largest potential market for organ transplants in the world, but it has not yet established brain death and organ transplant laws. We aimed to investigate the attitudes and suggestions of doctors, pharmacists, and civil servants concerning brain death, organ transplantation, and their respective legislation. METHODS: A questionnaire with 10 sections and 44 questions was designed and distributed. The effective questionnaire data were then recorded and checked for descriptive analysis. RESULTS: In 1400 questionnaires distributed, 1063 were responded and 969 of them were valid and analyzed. The respondents showed an incomplete understanding of brain death and organ transplantation laws. Seventy-four percent of the respondents recognized and accepted the standard of brain death. They agreed that legislation should be involved in the removal of organs for transplantation, the future use of organs, and insurance and compensation for the donor for possible health risks induced by organ removal. Of the 969 respondents, 92%considered it necessary to have legislation in brain death and organ transplantation, and 61% thought that it is time to legislate. CONCLUSIONS: Legislation for brain death and organ transplantation is urgent and timely in China. The laws must include the respective rights and obligations of patients, close relatives, and medical institutions. Educating the public about brain death and organ transplantation should also be encouraged in a variety of ways.

  7. SuperHILAC Upgrade Project

    Energy Technology Data Exchange (ETDEWEB)

    Feinberg, B.; Brown, I.G.

    1986-06-01

    A high current MEtal Vapor Vacuum Arc (MEVVA) ion source is to be installed in the third injector (Abel) at the SuperHILAC, representing the first accelerator use of this novel ion source. The MEVVA source has produced over 1 A of uranium in all charge states, with typically more than 100 electrical mA (emA) of U/sup 5 +/. A substantial fraction of this high current, heavy ion beam must be successfully transported to the entrance of the Wideroe linac to approach the 10 emA space-charge output limit of the Wideroe. Calculations show that up to 50 emA of U/sup 5 +/ can be transported through the present high voltage column. A bouncer will be added to the Cockcroft-Walton supply to handle the increased beam current. The Low Energy Beam Transport line vacuum will be improved to reduce charge exchange, and the phase matching between the 23 MHz Wideroe and the 70 MHz Alvarez linacs will be improved by the addition of two 70 HMz bunchers. The installation of the MEVVA source along with the modifications described above are expected to result in a five-fold increase in beam delivered to Bevatron experiments, increasing the extracted uranium beam to 5 x 10/sup 7/ ions/pulse.

  8. Super-B Project Overview

    Energy Technology Data Exchange (ETDEWEB)

    Biagini, M.E.; Boni, R.; Boscolo, M.; Demma, T.; Drago, A.; Guiducci, S.; Raimondi, P.; Tomassini, S.; Zobov, M.; /Frascati; Bertsche, K.; Donald, M.; Nosochkov, Y.; Novokhatski, A.; Seeman, J.; Sullivan, M.; Yocky, G.; Wienands, U.; Wittmer, W.; /SLAC; Koop, I.; Levichev, E.; Nikitin, S.; /Novosibirsk, IYF /KEK, Tsukuba /Pisa U. /CERN

    2010-08-26

    The SuperB project aims at the construction of an asymmetric very high luminosity B-Factory on the Frascati/Tor Vergata (Italy) area, providing a uniquely sensitive probe of New Physics in the flavour sector of the Standard Model. The luminosity goal of 10{sup 36} cm{sup -2} s{sup -1} can be reached with a new collision scheme with 'large Piwinski angle' (LPA) and the use of 'crab waist sextupoles' (CW). A LPA&CW Interaction Region (IR) has been successfully tested at the DA{Phi}NE {Phi}-Factory at LNF-Frascati in 2008. The LPA&CW scheme, together with very low {beta}*, will allow for operation with relatively low beam currents and reasonable bunch length, comparable to those of PEP-II and KEKB. In the High Energy Ring (HER), two spin rotators will bring longitudinally polarized beams into collision at the IP. The lattice has been designed with a very low intrinsic emittance and is quite compact, less than 2 km long. The tight focusing requires the final doublet quadrupoles to be very close to the IP and very compact. A Conceptual Design Report was published in March 2007, and beam dynamics and collective effects R&D studies are in progress in order to publish a Technical Design Report by the end of 2010.

  9. SUPER-B LATTICE STUDIES

    Energy Technology Data Exchange (ETDEWEB)

    Biagini, M.E.; Raimondi, P.; /Frascati; Piminov, P.; Sinyatkin, S.; /Novosibirsk, IYF; Nosochkov, Y.; Wittmer, W.; /SLAC

    2010-08-25

    The SuperB asymmetric e{sup +}e{sup -} collider is designed for 10{sup 36} cm{sup -2} s{sup -1} luminosity and beam energies of 6.7 and 4.18 GeV for e{sup +} and e{sup -} respectively. The High and Low Energy Rings (HER and LER) have one Interaction Point (IP) with 66 mrad crossing angle. The 1258 m rings fit to the INFN-LNF site at Frascati. The ring emittance is minimized for the high luminosity. The Final Focus (FF) chromaticity correction is optimized for maximum transverse acceptance and energy bandwidth. Included Crab Waist sextupoles suppress betatron resonances induced in the collisions with a large Piwinski angle. The LER Spin Rotator sections provide longitudinally polarized electron beam at the IP. The lattice is flexible for tuning the machine parameters and compatible with reusing the PEP-II magnets, RF cavities and other components. Details of the lattice design are presented.

  10. Studies of the Super VELO

    CERN Document Server

    AUTHOR|(CDS)2156302

    2016-01-01

    The Super VELO is the Run 5 upgrade of the VeloPix detector of the LHCb experiment. Its most challenging task is to cope with a luminosity increase of the factor 10. This study examines the potential physics performance of a detector based on the VeloPix design at high luminosity conditions. It is found that an unmodified VeloPix detector shows poor performance when exposed to 10x design luminosity, most gravely high ghost rates of 40 %. When applying basic assumptions about material changes such as cutting the silicon thickness by half and removing the RF foil, the ghost rate drops by 20 %. When using thin silicon and re-optimizing the tracking algorithm, the ghost rate can even be reduced by 60 %. Applying the additional modification of a pixel area size four times smaller, the ghost rate drops by 88 % and the IP resolution improves. Finally, in a dream scenario with thin silicon, smaller pixels and no RF foil, big gains in resolution and a ghost rate of less than 4 % can be achieved.

  11. ALLOCATION OF MINI UNMANNED AERIAL VEHICLES FOR URGENT INTELLIGENCE, SURVEILLANCE AND RECONNAISSANCE REQUEST

    Directory of Open Access Journals (Sweden)

    Ömer Faruk KURBAN

    2016-01-01

    Full Text Available Urgent intelligence, surveillance and reconnaissance request has the priority for all security forces while intervening in the events. The objective of this project is to locate grand control location of Mini Unmanned Aerial Vehicle units which has different coverage capabilities, responsible for obtaining urgent intelligence, surveillance and reconnaissance the problem of finding the optimum locations of mini Unmanned Aerial Vehicle units is modeled firstly under no effect of changing weather and environmental circumstances as a Maximal Co- vering Location Problem and secondly by putting into the effect of changing weather and environmental circumstances as a Maximum Expected Covering Location problem. Totally seventeen different scenarios are developed for both model, five for Maximal Covering Lo- cation problem and twelve for Maximum Expected Covering Location problem. Optimal solutions were found by using GAMS. Finally, the changes in the optimal solutions are analyzed by altering the problem parameters.

  12. The therapeutic itinerary in urgent/emergency pediatric situations in a Maroon community.

    Science.gov (United States)

    Siqueira, Samylla Maira Costa; Jesus, Viviane Silva de; Camargo, Climene Laura de

    2016-01-01

    The goal was to understand the therapeutic itinerary of Maroon children in urgent/emergency situation. Is a descriptive research with a qualitative approach that uses the Health Care System model of Arthur Kleinman as its theoretical support. Participants included 12 mothers of children who had experienced any urgent or emergency medical situation. Data collection took place from December 2013 to June 2014 through semi-structured interviews with a thematic analysis of the data. The care of the child started in the "informal" subsystem, and access to a "formal" subsystem was characterized as a pilgrimage for health services. A development of specific strategies is needed to ensure and facilitate full access to the services of the professional subsystem for Maroon communities.

  13. Urgent awake thoracoscopic treatment of retained haemothorax associated with respiratory failure

    OpenAIRE

    Pompeo, Eugenio; Cristino, Benedetto; Rogliani, Paola; Dauri, Mario

    2015-01-01

    A number of video-assisted thoracoscopic surgery (VATS) procedures are being increasingly performed by awake anesthesia in an attempt of minimizing the surgical- and anesthesia-related traumas. However, so far the usefulness of awake VATS for urgent management of retained haemothorax has been scarcely investigated. Herein we present two patients with retained haemothorax following previous thoracentesis and blunt chest trauma, respectively, who developed acute respiratory failure and underwen...

  14. Adverse drug reactions leading to urgent hospital admission in an elderly population: prevalence and main features.

    Science.gov (United States)

    Pedrós, Consuelo; Formiga, Francesc; Corbella, Xavier; Arnau, Josep Maria

    2016-02-01

    To assess the prevalence of urgent hospitalization due to adverse drug reactions (ADRs) in patients aged ≥ 65 years, to compare the in-hospital mortality rates between patients admitted for ADRs and those admitted for other causes, and to describe the ADRs, the used and suspected drugs, and the drug-reaction associations. A cross-sectional study was conducted by using the institutional database of the Pharmacovigilance Programme of Bellvitge University Hospital, a 750-bed tertiary care hospital, with information corresponding to a 7-year period. ADR-related admissions of patients aged ≥ 65 years prospectively identified through a systematic daily review of all admission diagnosis were reviewed. ADRs were suspected to be the main reason for urgent admission in 1976 out of 60,263 patients aged ≥ 65 years (prevalence of ADR-related hospitalization 3.3 % [95 % CI 3.1-3.4 %]). The crude in-hospital mortality rate was 10.2 % in patients with ADR-related admission and 9 % in patients admitted for other causes (p = 0.077). Most patients (86 %) were exposed to polypharmacy, and a drug-drug interaction was suspected in 49 % of cases. The most frequent drug-reaction associations were acute renal failure related to renin-angiotensin system inhibitors, gastrointestinal bleeding caused by antithrombotics and/or non-steroidal anti-inflammatories, and intracranial bleeding induced by vitamin K antagonists. One out of every 30 urgent admissions of patients aged ≥ 65 years is ADR-related. These ADRs can be as serious and life-threatening as any other acute pathology that merits urgent hospital admission. Most cases involve patients exposed to polypharmacy and result from well-known reactions of a few commonly used drugs.

  15. Use of Abdominopelvic Computed Tomography in Emergency Departments and Rates of Urgent Diagnoses in Crohn's Disease

    Science.gov (United States)

    Kerner, Caroline; Carey, Kathleen; Mills, Angela M.; Yang, Wei; Synnestvedt, Marie B.; Hilton, Susan; Weiner, Mark G.; Lewis, James D.

    2013-01-01

    Background & Aims In the United States, the use of abdominopelvic computed tomography (APCT) by emergency departments for patients with abdominal pain has increased, despite stable admission rates and diagnosis requiring urgent intervention. We proposed that trends would be similar for patients with Crohn's disease (CD). Methods We conducted a retrospective study of data from 648 adults with CD who presented at 2 emergency departments (2001–2009; 1572 visits). Trends in APCT use were assessed with Spearman's correlation coefficient. We compared patient characteristics and APCT findings during 2001–2003 and 2007–2009. Results APCT use increased from 2001 (used for 47% of encounters) to 2009 (used for 78% of encounters; P=.005), whereas admission rates were relatively stable, at 68% in 2001 and 71% in 2009 (P=.06). The overall proportion of APCTs with findings of intestinal perforation, obstruction, or abscess was 29.0%; 34.9% of APCTs were associated with urgent diagnoses, including those unrelated to CD. Between 2001–2003 and 2007–2009, the proportions of APCTs that detected intestinal perforation, obstruction, or abscess were similar (30% vs 29%, P=.92), as were the proportions used detecting any diagnosis requiring urgent intervention, including those unrelated to CD (36% vs 34%, P=.91). Conclusions Despite the increased use of APCT by emergency departments for patients with CD, there were no significant change in admission rates between the periods of 2001–2003 and 2007–2009. The proportion of APCTs that detected intestinal perforation, obstruction, abscess, or other urgent conditions not related to CD remained high. PMID:23552763

  16. Urgent resection of bleeding congenital mesenchymal chest wall hamartoma in an infant

    OpenAIRE

    Bieda, Jan-Christoph; Tröbs, Ralf-Bodo; Roll, Claudia; Wunsch, Rainer; Neid, Matthias

    2013-01-01

    We report a case with prenatally diagnosed large cystic-solid mesenchymal chest wall hamartoma. An attempt of conservative management was made however repeated intralesional hemorrhage led to enlargement and severe anemia which required urgent resection at the age of 8 weeks. The infant had an unimpaired development over a follow-up of 4 years. Wir berichten über ein Neugeborenes mit einem bereits pränatal diagnostizierten, ausgedehnten Thoraxwand-Hamartom von zystisch-solider Beschaffen...

  17. Predictive monitoring for respiratory decompensation leading to urgent unplanned intubation in the neonatal intensive care unit.

    Science.gov (United States)

    Clark, Matthew T; Vergales, Brooke D; Paget-Brown, Alix O; Smoot, Terri J; Lake, Douglas E; Hudson, John L; Delos, John B; Kattwinkel, John; Moorman, J Randall

    2013-01-01

    Infants admitted to the neonatal intensive care unit (NICU), and especially those born with very low birth weight (VLBW; endotracheal intubation and mechanical ventilation. Intubation and mechanical ventilation are associated with increased morbidity, particularly in urgent unplanned cases. We tested the hypothesis that the systemic response associated with respiratory decompensation can be detected from physiological monitoring and that statistical models of bedside monitoring data can identify infants at increased risk of urgent unplanned intubation. We studied 287 VLBW infants consecutively admitted to our NICU and found 96 events in 51 patients, excluding intubations occurring within 12 h of a previous extubation. In order of importance in a multivariable statistical model, we found that the characteristics of reduced O(2) saturation, especially as heart rate was falling; increased heart rate correlation with respiratory rate; and the amount of apnea were all significant independent predictors. The predictive model, validated internally by bootstrap, had a receiver-operating characteristic area of 0.84 ± 0.04. We propose that predictive monitoring in the NICU for urgent unplanned intubation may improve outcomes by allowing clinicians to intervene noninvasively before intubation is required.

  18. A nurse practitioner-led urgent care center: meeting the needs of the patient with cancer.

    Science.gov (United States)

    Ruegg, Tracy A

    2013-08-01

    Providing comprehensive care for patients with cancer is complex with regard to severe treatment-related side effects. Hundreds of thousands of patients with cancer visit the emergency department (ED) each year, and more than half report multiple visits. In the United States, few of the National Cancer Institute-designated cancer centers have an ED specifically for patients with cancer. EDs often are an overcrowded and expensive way in which to care for the urgent needs of patients with cancer. In addition, a looming shortage exists for both primary care providers and oncologists who can address symptom issues. As the Affordable Care Act is implemented, more patients will enter the healthcare system, placing a demand on providers that the current supply cannot meet. A report from the Institute of Medicine advocates that nurse practitioners (NPs) are more than competent to provide for the unique urgent care needs of patients with cancer. The aim of this article is to describe an NP-led urgent care center for patients with cancer and how that care center provides access to vital, expeditious, and cost-effective care.

  19. Cerebral oxygenation monitoring in patients with bilateral carotid stenosis undergoing urgent cardiac surgery: Observational case series

    Directory of Open Access Journals (Sweden)

    Dincer Aktuerk

    2016-01-01

    Full Text Available Background: Patients with significant bilateral carotid artery stenosis requiring urgent cardiac surgery have an increased risk of stroke and death. The optimal management strategy remains inconclusive, and the available evidence does not support the superiority of one strategy over another. Materials and Methods: A number of noninvasive strategies have been developed for minimizing perioperative stroke including continuous real-time monitoring of cerebral oxygenation with near-infrared spectroscopy (NIRS. The number of patients presenting with this combination (bilateral significant carotid stenosis requiring urgent cardiac surgery in any single institution will be small and hence there is a lack of large randomized studies. Results: This case series describes our early experience with NIRS in a select group of patients with significant bilateral carotid stenosis undergoing urgent cardiac surgery (n = 8. In contrast to other studies, this series is a single surgeon, single center study, where the entire surgery (both distal ends and proximal ends was performed during single aortic clamp technique, which effectively removes several confounding variables. NIRS monitoring led to the early recognition of decreased cerebral oxygenation, and corrective steps (increased cardiopulmonary bypass flow, increased pCO 2 , etc., were taken. Conclusion: The study shows good clinical outcome with the use of NIRS. This is our "work in progress," and we aim to conduct a larger study.

  20. Urgent hybrid approach in treatment of the acute myocardial infarction complicated by the ventricular septal rupture

    Directory of Open Access Journals (Sweden)

    Radosavljević-Radovanović Mina

    2014-01-01

    Full Text Available Introduction. Ventricular septal rupture (VSR in the acute myocardial infarction (AMI is a rare but very serious complication, still associated with high mortality, despite significant improvements in pharmacological and surgical treatment. Therefore, hybrid approaches are introduced as new therapeutical options. Case Outline. We present an urgent hybrid approach, consisting of the initial percutaneous coronary intervention (PCI of the infarct-related artery, followed by immediate surgical closure of the ventricular septal rupture, for treatment of high risk, hemodynamically unstable female patient with AMI caused by one-vessel disease and complicated by VSR and cardiogenic shock. Since the operative risk was also very high (EUROSCORE II 37%, this therapeutic decision was based on the assumption that preoperative PCI could promptly establish blood flow and thereby lessen the risks, duration and complexity of urgent cardiosurgical intervention, performed on the same day. This approach proved to be successful and the patient was discharged from the hospital on the fifteenth postoperative day in stable condition. Conclusion. In selected cases, with high operative risk and unstable hemodynamic state due to AMI complicated by VSR, urgent hybrid approach consisting of the initial PCI followed by surgical closure of VSR may represent an acceptable treatment option and contribute to the treatment of this complex group of patients.

  1. Urgent Protection versus Chronic Need: Clarifying the Dual Mandate of Child Welfare Services across Canada

    Directory of Open Access Journals (Sweden)

    Nico Trocmé

    2014-08-01

    Full Text Available This study analyzed data from the 1998, 2003 and 2008 Canadian Incidence Study of reported child abuse and neglect (CIS and compared the profile of children who were reported for an urgent protection investigation versus any other investigation or assessment. As a proportion of all investigations, urgent protection cases have dropped from 28% of all investigations in 1998, to 19% in 2003, to 15% in 2008. Results from the CIS-2008 analysis revealed that 7% of cases involved neglect of a child under four, 4% of cases involved sexual abuse, 2% of cases involved physical abuse of a child under four and 1% of cases involved children who had sustained severe enough physical harm that medical treatment was required. The other 85% of cases of investigated maltreatment involved situations where concerns appear to focus less on immediate safety and more on the long-term effects of a range of family related problems. These findings underscore the importance of considering the dual mandate of child welfare mandates across Canada: intervening to assure the urgent protection and safety of the child versus intervening to promote the development and well-being of the child.

  2. [The experience of kidney transplantation at the Donetsk transplantation center].

    Science.gov (United States)

    Serniak, P S; Denisov, V K; Zakharov, V V; Oleshchenko, N D; Guba, G B; Rodin, I N; Chernobrivtsev, P A; Derkach, I A

    1999-01-01

    In Donetskiy transplantational centre during the period from 1986 to 1996 yr were conducted 305 operations of the kidney transplantation from the cadaveric and living donor. Kidney transplantation permits to achieve higher level of rehabilitation than while application of hemodialysis and must become the method of choice in treatment of terminal stage of chronic renal insufficiency. Considering large demand for the organs transplantation in Ukraine it is necessary to create an economically substantiated programme "Transplantation of organs".

  3. Outcomes of renal patients from the Ivory Coast transplanted abroad: time for a local kidney transplantation program.

    Science.gov (United States)

    Ackoundou-N'Guessan, C; Gnionsahe, D A; Dekou, A H; Tia, W M; Guei, C M; Moudachirou, A M

    2010-11-01

    The outcomes of transplanted kidney recipients from "transplant tourism" have been reported to be alarming. The present study was an attempt to examine the results of renal patients from the Ivory Coast transplanted abroad returning home for follow-up. This retrospective analysis includes renal patients from the Ivory Coast transplanted abroad between 1995 and 2009 and followed up by our nephrology clinic. We collected pre- and posttransplant parameters for statistical analyses. The 16 patients had a median age of 48 years (range = 32.5-53.75). The median age of kidney donors was 44 years (range = 30.75-51.25). Initial kidney disease was hypertension in 10 patients (62.5%) and diabetes in three patients (18.8%). They received organs from living donors (37.5% related [LRD] and 37.5% unrelated [LURD]). Initial immunosuppression consisted of induction (72.7%), tacrolimus (75%), and mycophenolate mofetil (100%). Two patients (12.5%) experienced late acute rejections, resulting in graft loss. The overall graft survival was 93% at 1 year and 80% at 5 years. Five patients died over the study period, corresponding to an overall mortality rate of 9.25/100 patient-years. The overall median patient survival was 6.25 years (range = 4.19-7.58). Patient survivals at 1 and 5 years were 93% and 53%, respectively. No factors seemed to influence survival (either graft or patient) upon multivariate analysis. Comparison between LRD and LURD recipients revealed no statistical difference among posttransplant characteristics and survivals. Mortality of renal patients from the Ivory Coast transplanted abroad is high. Financial exhaustion after transplantation renders follow-up precarious. A local kidney transplantation program in the Ivory Coast appears more urgent than ever. Copyright © 2010 Elsevier Inc. All rights reserved.

  4. Syngeneic transplantation in aplastic anemia

    DEFF Research Database (Denmark)

    Gerull, Sabine; Stern, Martin; Apperley, Jane

    2013-01-01

    Aplastic anemia is usually treated with immunosuppression or allogeneic transplant, depending on patient and disease characteristics. Syngeneic transplant offers a rare treatment opportunity with minimal transplant-related mortality, and offers an insight into disease mechanisms. We present here...... a retrospective analysis of all syngeneic transplants for aplastic anemia reported to the European Group for Blood and Marrow Transplantation. Between 1976 and 2009, 88 patients received 113 transplants. Most transplants (n=85) were preceded by a conditioning regimen, 22 of these including anti-thymocyte globulin...

  5. Endovascular management in liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Kyu-Bo Sung

    2006-01-01

    @@ Liver transplantation was developed for the treatment of hepatic failure, and the first human liver transplantation was done in 1963. From the 1990 s,liver transplantation was generally accepted as a treatment modality for both end-stage liver disease and selected liver malignancies. Initially, liver transplantation was started with deceased donor whole-size liver transplantation (whole-size LT) as in other organ transplantation, but there is now a shortage of deceased liver donors has occurred. As a solution, deceased donor split liver transplantation (split LT) began in 1989 and living donor liver transplantation (LDLT) in the early 1990 s. Current liver transplantation techniques include whole-size LT, reduced-size liver transplantation (reduced-size LT), split LT and single or dual LDLT. Two donors give a part of their livers to one adult recipient simultaneously in dual LDLT.

  6. Super-multiplex vibrational imaging

    Science.gov (United States)

    Wei, Lu; Chen, Zhixing; Shi, Lixue; Long, Rong; Anzalone, Andrew V.; Zhang, Luyuan; Hu, Fanghao; Yuste, Rafael; Cornish, Virginia W.; Min, Wei

    2017-04-01

    potential of this 24-colour (super-multiplex) optical imaging approach for elucidating intricate interactions in complex biological systems.

  7. Patient selection for liver transplantation.

    Science.gov (United States)

    Carrion, Andres F; Aye, Lydia; Martin, Paul

    2013-08-01

    Improved outcomes in liver transplant recipients reflect advances in surgical technique, post-operative care, immunosuppression as well as better selection of potential candidates. The pre-transplant evaluation is a multidisciplinary process intended to recognize and treat important comorbid conditions that may impair outcomes during the peri- and post-transplant periods. Important psychosocial issues should also be ascertained and tackled early during the pre-transplant evaluation with an overarching intention to improve the success of liver transplantation.

  8. Islet transplantation: immunological perspectives.

    Science.gov (United States)

    Inverardi, Luca; Kenyon, Norma S; Ricordi, Camillo

    2003-10-01

    Clinical trials of islet transplantation are showing remarkable success, but they require administration of chronic immunosuppression, and are underscoring the large gap that exists between the number of human donors available and the number of patients that could benefit from the procedure. Recent progress has been made in the definition of key immunological mechanisms that are involved in determining islet transplant outcome. Clinical and preclinical studies, and studies in small animal model systems, will all eventually contribute to the definition of efficient and safe protocols for islet transplantation. If the use of xenografts is successful, it might represent a solution to the shortage of human organs.

  9. Pediatric transplantation: preventing thrombosis.

    Science.gov (United States)

    Robertson, J D

    2015-06-01

    Due to progressive advances in surgical techniques, immunosuppressive therapies, and supportive care, outcomes from both solid organ transplantation and hematopoietic stem cell transplantation continue to improve. Thrombosis remains a challenging management issue in this context, with implications for both graft survival and long-term quality of life. Unfortunately, there remains a general paucity of pediatric-specific data regarding thrombosis incidence, risk stratification, and the safety or efficacy of preventative strategies with which to guide treatment algorithms. This review summarizes the available evidence and rationale underlying the spectrum of current practices aimed at preventing thrombosis in the transplant recipient, with a particular focus on risk factors, pathophysiology, and described antithrombotic regimens.

  10. Pancreatic islet transplantation

    Directory of Open Access Journals (Sweden)

    Corrêa-Giannella Maria

    2009-09-01

    Full Text Available Abstract Background No formulation of exogenous insulin available to date has yet been able to mimic the physiological nictemeral rhythms of this hormone, and despite all engineering advancements, the theoretical proposal of developing a mechanical replacement for pancreatic β cell still has not been reached. Thus, the replacement of β cells through pancreas and pancreatic islet transplantation are the only concrete alternatives for re-establishing the endogenous insulin secretion in type 1 diabetic patients. Since only 1 to 1.5% of the pancreatic mass corresponds to endocrine tissue, pancreatic islets transplantation arises as a natural alternative. Data from the International Islet Transplant Registry (ITR from 1983 to December 2000 document a total of 493 transplants performed around the world, with progressively worse rates of post-transplant insulin independence. In 2000, the "Edmonton Protocol" introduced several modifications to the transplantation procedure, such as the use of a steroid-free immunosuppression regimen and transplantation of a mean islet mass of 11,000 islet equivalents per kilogram, which significantly improved 1-year outcomes. Although the results of a 5-year follow-up in 65 patients demonstrated improvement in glycemic instability in a significant portion of them, only 7.5% of the patients have reached insulin independence, indicating the need of further advances in the preservation of the function of transplanted islet. In addition to the scarcity of organs available for transplantation, islets transplantation still faces major challenges, specially those related to cell loss during the process of islet isolation and the losses related to the graft site, apoptosis, allorejection, autoimmunity, and immunosuppression. The main strategies to optimize islet transplantation aim at improving all these aspects. Conclusion Human islet transplantation should be regarded as an intervention that can decrease the frequency of

  11. DONOR HEART VALVES RECONSTRUCTION BEFORE TRANSPLANTATION

    Directory of Open Access Journals (Sweden)

    S. V. Gautier

    2013-01-01

    Full Text Available Aim of study. The demonstration of our own experience in heart transplantation after valve reconstruction. Methods and results. From May 2012 to March 2013 3 mitral valve annuloplasties were performed to recipi- ents, requiring urgent HT and having extremely unfavorable prognosis of survival without HT. The recipients were classified as United Network for Organ Sharing (UNOS IB, and all of them were on inotropic support. In one case, HT was performed after reconstruction of rheumatic mitral stenosis, in two other cases – after dege- nerative mitral regurgitation. The technical aspects are reviewed of ex-vivo mitral and tricuspid valves repair with concomitant heart transplantation. All patients were discharged from the hospital having excellent postope- rative recovery. Conclusion. Taking into consideration the demonstrated satisfactory result of surveillance and presence of significant experience in performing of reconstructive valve surgery among no-HT cardiosurgical patients, an increase in the pool of suitable donor organs is expected due to the liberalization of the selection criteria and the possibility of the innovative valve reconstruction procedures ex vivo. 

  12. Protective effect of glycine on liver injury during liver transplantation

    Institute of Scientific and Technical Information of China (English)

    WANG Yao-sheng; YAN Ye-hong; ZOU Xun-feng

    2010-01-01

    @@ Multiple procedures of liver transplantation bring conditions producing cold ischemia-reperfusion (I/R) injury. During cold storage, the graft organ is subjected to cold ischemia, also known as hypoxia injury. After reperfusion, although hypoxic condition has been ameliorated, reoxygenation of the graft liver can produce not only reperfusion injury including generation of oxygen free radical, lipoperoxidation and calcium overload, but also aggravate the hypoxia damage, involving endothelial cell (EC) damage, Kupffer cell (KC) activation, and adherence of neutrophils and platelets to Ecs. Clinically, I/R injury is one of the major problems complicating liver transplantation, and can ultimately result in serious complications such as primary nonfunction and delayed graft function, which may lead to the need of urgent retransplantation. Therefore, the therapeutic strategies of attenuating graft I/R injury are clinically significant and might improve overall graft function and survival.

  13. Pseudomembranous colitis in four patients with cystic fibrosis following lung transplantation.

    Science.gov (United States)

    Yates, B; Murphy, D M; Fisher, A J; Gould, F K; Lordan, J L; Dark, J H; Corris, P A

    2007-06-01

    Pseudomembranous colitis is an uncommon complication in patients with cystic fibrosis, despite the use of multiple high-dose antibiotic regimens and the frequency of hospital admissions. Four patients from a total of 137 patients with cystic fibrosis undergoing lung transplantation are described who developed fulminant pseudomembranous colitis. Initial presentation was variable and the mortality rate was 50% despite urgent colectomy. In one case the presenting abdominal distension was thought to be due to meconium ileus equivalent. It is concluded that Clostridium difficile colitis may be a difficult diagnosis in patients with cystic fibrosis and follows a fulminant course after lung transplantation.

  14. Axial super-resolution evanescent wave tomography.

    Science.gov (United States)

    Pendharker, Sarang; Shende, Swapnali; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-12-01

    Optical tomographic reconstruction of a three-dimensional (3D) nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography method that enables the use of regular evanescent wave microscopes like the total internal reflection fluorescence microscope beyond surface imaging and achieve a tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of 3D fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by one-dimensional (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axial resolution of ∼130  nm. Our method does not require any additional optical components or sample preparation. The proposed method can be combined with focal plane super-resolution techniques like stochastic optical reconstruction microscopy and can also be adapted for THz and microwave near-field tomography.

  15. Axial super-resolution evanescent wave tomography

    Science.gov (United States)

    Pendharker, Sarang; Shende, Swapnali; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-12-01

    Optical tomographic reconstruction of a 3D nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography (AxSET) method that enables the use of regular evanescent wave microscopes like Total Internal Reflection Fluorescence Microscope (TIRF) beyond surface imaging, and achieve tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of three-dimensional fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by 1D (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axial resolution of $\\sim$130 nm. Our method does not require any additional optical components or sample preparation. The proposed method can be combined with focal plane super-resolution techniques like STORM and can also be adapted for THz and microwave near-field tomography.

  16. Effect of Different Seeding and Transplanting Dates on Tillering Characteris-tics of Super IndicaHybrid Rice with Mechanized Seeding and Planting and Its Relationships with Meteorological Factors%播栽期对机插超级杂交籼稻分蘖成穗的影响及与气象因子的关系

    Institute of Scientific and Technical Information of China (English)

    钟晓媛; 赵敏; 李俊杰; 陈多; 田青兰; 王丽; 黄光忠; 任万军

    2016-01-01

    为探讨不同播栽期对机插超级杂交籼稻分蘖成穗的影响,以2个超级杂交籼稻品种F优498和宜香优2115为材料,设置3月21日(S1)、3月31日(S2)、4月10日(S3)、4月20日(S4)和4月30日(S5)5个播期,秧龄均为30 d,移栽期依次为4月21日、5月1日、5月11日、5月21日和5月31日,研究其分蘖发生成穗特点及与气象因子的关系。结果表明,不同播栽期水稻产量差异显著,随着播栽期推迟,产量呈降低趋势,早播 S1的产量最高、迟播S5的产量最低。不同播栽期处理下水稻主茎对产量的贡献表现为(S1~S4) S5, S1优势蘖位为第3~第6叶,而S2~S5优势蘖位为第3~第5叶。随播栽期推迟,分蘖发生和成穗叶位趋于集中, F优498一次分蘖发生在S1~S4以3/0~7/0为主,而在S5以3/0~6/0为主;宜香优2115在S1以3/0~7/0为主,在S2~S5以3/0~6/0为主。一次分蘖成穗率在S1以3/0~6/0为主,而在S2~S5以3/0~5/0为主;二次分蘖发生和成穗以第3~第4叶为主。气象因子对分蘖发生和成穗的影响为一、二次分蘖发生率与日平均相对湿度呈显著负相关,而与平均气温日较差、积温、日照时数呈显著或极显著正相关;一次分蘖成穗率与分蘖期日平均相对湿度、平均气温呈显著负相关,与分蘖期平均气温日较差、积温、日照时数呈显著正相关,与幼穗分化期日平均相对湿度呈显著负相关,与抽穗开花期日照时数呈显著正相关。综合看来,成都平原地区机插超级杂交籼稻在4月11日前播种5月11日前移栽有利于产量的提高,在4月21日前播种5月21日前移栽有利于稳产,在4月21日以后播种5月21日后移栽产量显著降低。%In order to explore tillering characteristics and its relationships with meteorological factors in superindica hybrid rice with mechanized seeding and planting with different seeding and transplanting dates, a split plot field experiment was conducted using superindica hybrid rice F

  17. Pancreatic Islet Transplantation

    Science.gov (United States)

    ... and longer duration of organ function. The main disadvantage is that a whole organ transplant is a ... Privacy Policy Freedom of Information Act Accessibility Disclaimers Copyright Sitemap For Staff Only Jobs at NIDDK U.S. ...

  18. Kidney Transplantation in Iran

    Directory of Open Access Journals (Sweden)

    Behzad Einollahi

    2010-03-01

    Full Text Available Kidney transplantation in patients with end stage renal diseaseis preferred to dialysis because transplantation provides a betterquality of life and improved survival. However, the gapbetween the supply and demand for a renal allograft is wideningand the waiting time is increasing. Iranian protocol, a controlledtransplant program supported by the government forliving unrelated donors, was initiated for solving the problemof organ shortage. Although this system might experiencechallenges, clearly it has advantages over other organ procurementsystems primarily that thousands in need do not diewhile waiting for a compatible donor.In the present review I discuss the history of renal transplantationin Iran, "Iranian model" protocol, the situation ofIran’s kidney transplantation from either living or deceaseddonors compared with the Middle East countries, and our experiencesof unrelated renal transplantation.

  19. Neurologic Complications of Transplantation.

    Science.gov (United States)

    Dhar, Rajat

    2017-03-01

    Neurologic disturbances including encephalopathy, seizures, and focal deficits complicate the course 10-30% of patients undergoing organ or stem cell transplantation. While much or this morbidity is multifactorial and often associated with extra-cerebral dysfunction (e.g., graft dysfunction, metabolic derangements), immunosuppressive drugs also contribute significantly. This can either be through direct toxicity (e.g., posterior reversible encephalopathy syndrome from calcineurin inhibitors such as tacrolimus in the acute postoperative period) or by facilitating opportunistic infections in the months after transplantation. Other neurologic syndromes such as akinetic mutism and osmotic demyelination may also occur. While much of this neurologic dysfunction may be reversible if related to metabolic factors or drug toxicity (and the etiology is recognized and reversed), cases of multifocal cerebral infarction, hemorrhage, or infection may have poor outcomes. As transplant patients survive longer, delayed infections (such as progressive multifocal leukoencephalopathy) and post-transplant malignancies are increasingly reported.

  20. Pancreas transplant - slideshow

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/presentations/100129.htm Pancreas transplant - series—Normal anatomy To use the sharing ... to slide 6 out of 6 Overview The pancreas resides in the back of the abdomen. It ...

  1. Rabies in Transplant Recipients

    Centers for Disease Control (CDC) Podcasts

    2016-09-19

    Dr. Richard Franka, a CDC scientist, discusses rabies in organ transplant recipients.  Created: 9/19/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 9/19/2016.

  2. Experimental uterus transplantation.

    Science.gov (United States)

    Johannesson, Liza; Enskog, Anders

    2014-11-01

    Today, most causes of infertility are successfully treated. Yet there is still a subgroup of female infertility affecting around 4%, which so far is untreatable because of an absolute uterine factor. To acquire motherhood, these women are today referred to either adoption or surrogacy. Research in the field of uterus transplantation has been evaluated in different animal models for decades and has presently reached a human clinical application as a possible treatment for absolute uterine factor infertility. Organ transplantation is no longer reserved to those with a life-threatening disease and neither is organ transplantation together with concurrent immunosuppression prohibiting pregnancy. Uterus transplantation involves four parties - recipient, donor, partner of recipient and future child - and is a subject of ethical controversies.

  3. Imaging in transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Bankier, A.A. (ed.) [Harvard Medical School, Boston, MA (United States). Beth Israel Deaconess Medical Center

    2008-07-01

    This book covers all topics related to the imaging of organ transplantation. An introductory section addresses such issues as organ procurement, patient selection, immune responses, and ethical and economic considerations. The main part of the book then offers in-depth coverage of heart, renal, liver, lung, bone marrow and pancreatic and intestinal transplantation. Each of these topics is discussed firstly in a clinical chapter and then in a radiological chapter. The clinical chapters detail the epidemiology, clinical background, and surgical procedures, as well as any clinically relevant issues of which the radiologist should be aware. The radiological chapters describe and depict the imaging manifestations of specific organ transplantations, document the normal radiological appearance of transplanted organs and consider both early and late complications. This is a unique, superbly illustrated volume that will be of great assistance to all who work in this field. (orig.)

  4. Kidney Transplantation in Iran

    OpenAIRE

    2010-01-01

    Kidney transplantation in patients with end stage renal diseaseis preferred to dialysis because transplantation provides a betterquality of life and improved survival. However, the gapbetween the supply and demand for a renal allograft is wideningand the waiting time is increasing. Iranian protocol, a controlledtransplant program supported by the government forliving unrelated donors, was initiated for solving the problemof organ shortage. Although this system might experiencechallenges, clea...

  5. Faecal microbiota transplantation

    DEFF Research Database (Denmark)

    Jørgensen, Simon M D; Hansen, Mette Mejlby; Erikstrup, Christian

    2017-01-01

    BACKGROUND: Faecal microbiota transplantation (FMT) is currently being established as a second-line treatment for recurrent Clostridium difficile infection. FMT is further being considered for other infectious and inflammatory conditions. Safe and reproducible methods for donor screening, laborat......BACKGROUND: Faecal microbiota transplantation (FMT) is currently being established as a second-line treatment for recurrent Clostridium difficile infection. FMT is further being considered for other infectious and inflammatory conditions. Safe and reproducible methods for donor screening...

  6. Using tunneled femoral vein catheters for "urgent start" dialysis patients: a preliminary report.

    Science.gov (United States)

    Hingwala, Jay; Bhola, Cynthia; Lok, Charmaine E

    2014-01-01

    Multiple benefits of arteriovenous fistulas (AVF) and arteriovenous grafts (AVGs) exist over catheters. As part of a strategy to preserve thoracic venous sites and reduce internal jugular (IJ) vein catheter use, we inserted tunneled femoral vein catheters in incident "urgent start" dialysis patients while facilitating a more appropriate definitive dialysis access. "Urgent start" dialysis patients between January 15, 2013 and January 15, 2014 who required chronic dialysis, and did not have prior modality and vascular access plans, had tunneled femoral vein catheters inserted. We determined the femoral vein catheter associated infections rates, thrombosis, and subsequent dialysis access. Eligible patients were surveyed on their femoral vein catheter experience. Twenty-two femoral vein catheters were inserted without complications. Subsequently, one catheter required intraluminal thrombolytic locking, while all other catheters maintained blood flow greater than 300 ml/min. There were no catheter-related infections (exit site infection or bacteremia). Six patients continued to use their tunneled catheter at report end, one transitioned to peritoneal dialysis, thirteen to an arteriovenous graft, and two to a fistula. One patient received a tunneled IJ vein catheter. Of the patients who completed the vascular access survey, all indicated satisfaction with their access and that they had minimal complaints of bruising, bleeding, or swelling at their access sites. Pain/discomfort at the exit site was the primary complaint, but they did not find it interfered with activities of daily living. Femoral vein tunneled catheters appear to be a safe, well tolerated, and effective temporary access in urgent start dialysis patients while they await more appropriate long-term access.

  7. [Pelvi-perineal chronic pain, urgent demands of care and decision-making].

    Science.gov (United States)

    Quistrebert-Davanne, V; Boudoukha, A-H; Levesque, A; Guérin, P; Nizard, J; Labat, J-J

    2017-06-01

    Some patients suffering from pelvi-perineal chronic pain express urgent, even vital, demands of care. The objective was to compare the profile and the psychological functioning of the patients, who have shown an imperious demand of care, in that of the patients who do not have an imperious demand of care. From the medical consultations for chronic pelviperineal pain, we realized a comparative study including 26 patients (experimental group) expressing an urgent demand of care (i.e., patients who, during the last 3months, called an emergency service concerning the pains for which they consult in the service) and 28 patients (control group) without an urgent demand of care (i.e., patient who, during the last 3months, did not call an emergency service concerning the pains for which they consult in the service). All the patients were tested through a cognitive task of decision-making (Iowa Gambling Task) and through explicit measures of pain and its main psychological associated factors (anxiety, depression, impulsivity an catastrophism). In the first place, the patients from the experimental group possess decision-making abilities equivalent to the patients of the control group; however, both groups of patients show, in the beginning of the test, a deficit in the decision-making (F(4.208)=3.4116; P=.009). Secondly, the measures to questionnaires reveal that the patients of the control group have less severe scores in the scales of depression (t(52)=-2.068; Pcognitivo-behavioral techniques. 3. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  8. Urgent ERCP for acute cholangitis reduces mortality and hospital stay in elderly and very elderly patients

    Institute of Scientific and Technical Information of China (English)

    Chan Sun Park; Hee Seok Jeong; Ki Bae Kim; Joung-Ho Han; Hee Bok Chae; Sei Jin Youn; Seon Mee Park

    2016-01-01

    BACKGROUND: Acute cholangitis in old people is a cause of mortality and prolonged hospital stay. We evaluated the effects of methods and timing of biliary drainage on the outcomes of acute cholangitis in elderly and very elderly patients. METHODS: We analyzed 331 patients who were older than 75 years and were diagnosed with acute calculous cholangitis. They were admitted to our hospital from 2009 to 2014. Pa-tients’ demographics, severity grading, methods and timing of biliary drainage, mortality, and hospital stay were retrospec-tively obtained from medical records. Clinical parameters and outcomes were compared between elderly (75-80 years,n=156) and very elderly (≥81 years,n=175) patients. We analyzed the effects of methods [none, endoscopic retrograde cholangio-pancreatography (ERCP), percutaneous transhepatic biliary drainage, or failure] and timing (urgent or early) of biliary drainage on mortality and hospital stay in these patients. RESULTS: Acute cholangitis in older patients manifested as atypical symptoms characterized as infrequent Charcot’s triad (4.2%) and comorbidity in one-third of the patients. Patients were graded as mild, moderate, and severe cholangitis in 104 (31.4%), 175 (52.9%), and 52 (15.7%), respectively. Urgent bili-ary drainage (≤24 hours) was performed for 80.5% (247/307) of patients. Very elderly patients tended to have more severe grades and were treated with sequential procedures of tran-sient biliary drainage and stone removal at different sessions. Hospital stay was related to methods and timing of biliary drainage. Mortality was very low (1.5%) and not related to patient age but rather to the success or failure of biliary drainage and severity grading of the acute cholangitis. CONCLUSIONS: The methods and timing used for biliary drainage and severity of cholangitis are the major determi-nants of mortality and hospital stay in elderly and very elderly patients with acute cholangitis. Urgent successful ERCP is mandatory for

  9. Mobile pediatric neurosurgery: rapid response neurosurgery for remote or urgent pediatric patients.

    Science.gov (United States)

    Owler, Brian K; Carmo, Kathryn A Browning; Bladwell, Wendy; Fa'asalele, T Arieta; Roxburgh, Jane; Kendrick, Tina; Berry, Andrew

    2015-09-01

    Time-critical neurosurgical conditions require urgent operative treatment to prevent death or neurological deficits. In New South Wales/Australian Capital Territory patients' distance from neurosurgical care is often great, presenting a challenge in achieving timely care for patients with acute neurosurgical conditions. A protocol was developed to facilitate consultant neurosurgery locally. Children with acute, time-critical neurosurgical emergencies underwent operations in hospitals that do not normally offer neurosurgery. The authors describe the developed protocol, the outcome of its use, and the lessons learned in the 9 initial cases where the protocol has been used. Three cases are discussed in detail. Nine children were treated by a neurosurgeon at 5 rural hospitals, and 2 children were treated at a smaller metropolitan hospital. Road ambulance, fixed wing aircraft, and medical helicopters were used to transport the Newborn and Paediatric Emergency Transport Service (NETS) team, neurosurgeon, and patients. In each case, the time to definitive neurosurgical intervention was significantly reduced. The median interval from triage at the initial hospital to surgical start time was 3:55 hours, (interquartile range [IQR] 03:29-05:20 hours). The median distance traveled to reach a patient was 232 km (range 23-637 km). The median interval from the initial NETS call requesting patient retrieval to surgical start time was 3:15 hours (IQR 00:47-03:37 hours). The estimated median "time saved" was approximately 3:00 hours (IQR 1:44-3:15 hours) compared with the travel time to retrieve the child to the tertiary center: 8:31 hours (IQR 6:56-10:08 hours). Remote urgent neurosurgical interventions can be performed safely and effectively. This practice is relevant to countries where distance limits urgent access for patients to tertiary pediatric care. This practice is lifesaving for some children with head injuries and other acute neurosurgical conditions.

  10. COMPARATIVE ANALYSIS OF THE EFFECTIVENESS OF SUPER OVULATION IN BOTH LACTATING COWS AND REJECTED, SECURITY OF CALVES-TWINS Сравнительный анализ эффективности суперовуляции у лактирующих и выбракованных коров, сохранность телят-двоен

    Directory of Open Access Journals (Sweden)

    Vorobyev D. N.

    2012-02-01

    Full Text Available The article deals with the development of embryotransplantation and obtaining single and twin calves use of hormonal preparations FSH-Super and follotropin to provoke donors to super ovulation of folliculogenesis and embryos survival which were transplanted intocontralateral and ipsilateral uterine horn. Parameters of single and twin calves-transplantators’ growing in ontogenesis are also considered

  11. Umbilical cord blood transplantation.

    Science.gov (United States)

    Koo, Hong Hoe; Ahn, Hyo Seop

    2012-07-01

    Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disparity. Several studies have shown that the number of cells transplanted is the most important factor for engraftment in CBT, and it limits the wide use of CB in adult patients. New strategies for facilitating engraftment and reducing transplantation-related mortality are ongoing in the field of CBT and include the use of a reduced-intensity conditioning regimen, double-unit CBT, ex vivo expansion of CB, and co-transplantation of CB and mesenchymal stem cells. Recently, the results of two international studies with large sample sizes showed that CB is an acceptable alternative source of hematopoietic stem cells for adult recipients who lack human leukocyte antigen-matched adult donors. Along with the intensive researches, development in banking process of CB will amplify the use of CB and offer the chance for cure in more patients.

  12. Umbilical cord blood transplantation

    Directory of Open Access Journals (Sweden)

    Hong Hoe Koo

    2012-07-01

    Full Text Available Since the first umbilical cord blood transplantation (CBT in 1998, cord blood (CB has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disparity. Several studies have shown that the number of cells transplanted is the most important factor for engraftment in CBT, and it limits the wide use of CB in adult patients. New strategies for facilitating engraftment and reducing transplantation-related mortality are ongoing in the field of CBT and include the use of a reduced-intensity conditioning regimen, double-unit CBT, ex vivo expansion of CB, and co-transplantation of CB and mesenchymal stem cells. Recently, the results of two international studies with large sample sizes showed that CB is an acceptable alternative source of hematopoietic stem cells for adult recipients who lack human leukocyte antigen-matched adult donors. Along with the intensive researches, development in banking process of CB will amplify the use of CB and offer the chance for cure in more patients.

  13. Pregnancy and kidney transplantation.

    Science.gov (United States)

    Josephson, Michelle A; McKay, Dianne B

    2011-01-01

    Despite decades of experience with child bearing in women with kidney transplants, these pregnancies remain high risk with an increased prevalence of hypertension and pre-eclampsia. Infertility, common in women with end-stage renal disease, is rapidly restored after transplant although pregnancy rates appear lower in transplant recipients than the general public. Many unanswered questions exist, some old questions such as what is the optimal timing of pregnancy after transplant, whether breast feeding is safe, the long-term impact if any on the offspring, and whether pregnancy negatively affects the kidney graft; and some new questions such as whether to modify immunosuppression in a patient taking a mycophenolic acid-containing drug, whether kidney donation has a deleterious impact on future pregnancies, whether to use erythropoietin-stimulating agents, and the role of BK virus. Counseling about contraception and pregnancy after transplant should be initiated during the pretransplant evaluation process. It is important because of the rapid restoration of fertility that occurs after transplant as well as the many risks and unanswered questions that remain.

  14. Burnout in transplant nurses.

    Science.gov (United States)

    Jesse, Michelle T; Abouljoud, Marwan S; Hogan, Kathy; Eshelman, Anne

    2015-09-01

    Context-Burnout is a response to chronic strain within the workplace and is common across nursing professions. Little has been published about burnout in organ transplant nurses. Objective-To report the prevalence of the 3 main components of burnout (emotional exhaustion, depersonalization, and reduced personal accomplishment) in organ transplant nurses and to examine factors that contribute to the development of burnout in transplant nurses. Design-Cross-sectional survey of transplant nurses (recruited via listservs) on professional and personal demographics, decisional authority, psychological job demands, supervisor and coworker support, frequency and comfort with difficult patient interactions, and burnout. Participants-369 transplant nurses. Results-About half reported high levels of emotional exhaustion, 15.7% reported high levels of depersonalization, and 51.8% reported low levels of personal accomplishment. Working more hours per week, lower decisional authority, greater psychological job demands, lower perceived supervisor support, and greater frequency and discomfort with difficult patient interactions were significant predictors of emotional exhaustion. Greater frequency and discomfort with difficult patient interactions were significant predictors of depersonalization. Younger age, lower decisional authority, and greater discomfort with difficult patient interactions were predictors of low personal accomplishment. Conclusions-The study provides strong evidence of the presence of burnout in transplant nurses and opportunities for focused and potentially very effective interventions aimed at reducing burnout.

  15. Anesthetic management of a parturient with Stiff person syndrome for urgent cesarean delivery.

    Science.gov (United States)

    Boettcher, B T; Muravyea, M; Kuo, C; Drexler, C; Pagel, P S

    2016-08-01

    Stiff person syndrome is a rare neurologic disorder with an estimated incidence of 1:1000000. The underlying pathophysiology is truncal and proximal limb muscle stiffness resulting from continuous co-contracture of agonist and antagonist muscle groups concomitant with superimposed episodic muscle spasms. Loss of gamma-aminobutyric acid-mediated inhibition creates chronic excitation manifested by tonic agonist-antagonist muscle contraction. To date, only three case reports referred indirectly to the anesthetic management of parturients with Stiff person syndrome. The authors describe their management of a parturient with Stiff person syndrome who underwent urgent cesarean delivery under epidural anesthesia.

  16. Los Alamos National Laboratory: 21st century solutions to urgent national challenges

    Energy Technology Data Exchange (ETDEWEB)

    Mcbranch, Duncan [Los Alamos National Laboratory

    2008-01-01

    Los Alamos National Laboratory has been called upon to meet urgent national challenges for more than 65 years. The people, tools, and technologies at Los Alamos are a world class resource that has proved decisive through our history, and are needed in the future. We offer expertise in nearly every science, technology, and engineering discipline, a unique integrated capability for large-scale computing and experimentation, and the proven ability to deliver solutions involving the most complex and difficult technical systems. This white paper outlines some emerging challenges and why the nation needs Los Alamos, the premier National Security Science Laboratory, to meet these challenges.

  17. Social service in medicine in Mexico. An urgent and possible reform.

    Directory of Open Access Journals (Sweden)

    Gustavo Nigenda

    2013-09-01

    Full Text Available One third of the primary care units in the public system keeps being covered exclusively by interns. It is shown that with the resources available in the System for Social Protection in Health it is possible to hire graduate health personnel for all Ministry of Health rural units. It is necessary to modify the current legislation to impede an intern to be located in units without supervision of a graduate doctor. There is an urgent need for a reform of social service in medicine that responds both to the institutional modernization and to the increased capacity of the newly insured to demand high-quality services.

  18. Urgent-setting magnetic resonance imaging allows triage of extensive penoscrotal hematoma following blunt trauma

    Directory of Open Access Journals (Sweden)

    Massimo Tonolini

    2013-01-01

    Full Text Available Although uncommon, blunt trauma to the perineum may cause serious injury to the penis. Differentiation between penile fracture with torn tunica albuginea versus extratunical or cavernosal hematomas is crucial because the former condition needs early surgical repair to avoid future deformity and erectile dysfunction, whereas approach is conservative with even large penoscrotal hematomas with albugineal integrity. Urgent-setting magnetic resonance imaging including multiplanar images of the injured penoscrotal region allows precise identification or exclusion of presence, site, and extent of tears of the tunica albuginea, providing a consistent basis for therapeutic choice.

  19. La demanda atendida de consultas médicas y atención urgente

    OpenAIRE

    Álvarez, Begoña

    1998-01-01

    El objetivo de este artículo es estudiar los determinantes de la utilización de las consultas al médico y de la atención urgente en España. En el modelo teórico, los individuos se protegen frente a los riesgos financieros de la enfermedad contratando seguros sanitarios y producen salud a partir de una dotación exógena, combinando asistencia sanitaria y otros bienes de consumo cotidiano. La forma reducida de la demanda de asistencia sanitaria se estima a partir de los datos de la Encuesta Naci...

  20. Urgent endovascular treatment of proximal right subclavian artery pseudoaneurysm using kissing technique.

    Science.gov (United States)

    Zhang, Mi; Yuan, Ye; Hu, Yali; Zhao, Yi; Liu, Hui; Lu, Huijun

    2015-08-01

    A 50-year old man, sustained a blunt force injury to the chest during an engineering accident, underwent urgent endovascular angioplasty to treat proximal right subclavian artery pseudoaneurysm (RSAP) with a hostile neck in our hospital. Six-month follow-up showed that there was sufficient right carotid artery and right subclavian artery infusion, and the kissing stents were patent. The results show the safety and efficacy of kissing stent technique for RSAP in emergency patients who has no sufficient proximal fixation zone. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Assessing resolution in super-resolution imaging.

    Science.gov (United States)

    Demmerle, Justin; Wegel, Eva; Schermelleh, Lothar; Dobbie, Ian M

    2015-10-15

    Resolution is a central concept in all imaging fields, and particularly in optical microscopy, but it can be easily misinterpreted. The mathematical definition of optical resolution was codified by Abbe, and practically defined by the Rayleigh Criterion in the late 19th century. The limit of conventional resolution was also achieved in this period, and it was thought that fundamental constraints of physics prevented further increases in resolution. With the recent development of a range of super-resolution techniques, it is necessary to revisit the concept of optical resolution. Fundamental differences in super-resolution modalities mean that resolution is not a directly transferrable metric between techniques. This article considers the issues in resolution raised by these new technologies, and presents approaches for comparing resolution between different super-resolution methods.

  2. Architectural Engineering to Super-Light Structures

    DEFF Research Database (Denmark)

    Castberg, Niels Andreas

    with architectural engineering as a starting point. The thesis is based on a two stringed hypothesis: Architectural engineering gives rise to better architecture and Super-Light Structures support and enables a static, challenging architecture. The aim of the thesis is to clarify architectural engineering's impact...... on the work process between architects and engineers in the design development. Using architectural engineering, Super-Light Structures are examined in an architectural context, and it is explained how digital tools can support architectural engineering and design of Super-Light Structures. The experiences...... to be subjects of examination for this thesis. The research results show that architectural engineering has a significant impact on a design process. The projects illustrate that simple explanations, underpinned by visualisations of the challenges between shape versus structure, often creates a shared...

  3. Breeding Super-Earths and Birthing Super-Puffs in Transitional Disks

    CERN Document Server

    Lee, Eve J

    2015-01-01

    The riddle posed by super-Earths (1-4$R_\\oplus$, 2-20$M_\\oplus$) is that they are not Jupiters: their core masses are large enough to trigger runaway gas accretion, yet somehow super-Earths accreted atmospheres that weigh only a few percent of their total mass. We show that this puzzle is solved if super-Earths formed late, as the last vestiges of their parent gas disks were about to clear. This scenario would seem to present fine-tuning problems, but we show that there are none. Ambient gas densities can span many (up to 9) orders of magnitude, and super-Earths can still robustly emerge after $\\sim$0.1-1 Myr with percent-by-weight atmospheres. Super-Earth cores are naturally bred in gas-poor environments where gas dynamical friction has weakened sufficiently to allow constituent protocores to merge. So little gas is present at the time of core assembly that cores hardly migrate by disk torques: formation of super-Earths can be in situ. The picture --- that close-in super-Earths form in a gas-poor (but not ga...

  4. Low-grade proteinuria and microalbuminuria in renal transplantation.

    Science.gov (United States)

    Halimi, Jean-Michel

    2013-07-27

    Nephrotic-range proteinuria has been known for years to be associated with poor renal outcome. Newer evidence indicates that early (1-3 months after transplantation) low-grade proteinuria and microalbuminuria (1) provide information on the graft in terms of donor characteristics and ischemia/reperfusion injury, (2) may occur before the development of donor-specific antibodies, (3) predict the development of diabetes and cardiovascular events, and (4) are associated with reduced long-term graft and patient survivals. Low-grade proteinuria and microalbuminuria are also predictive of diabetes, cardiovascular morbidity, and death in nontransplanted populations, which may help us to understand the pathophysiology of low-grade proteinuria or microalbuminuria in renal transplantation. The impact of immunosuppressive medications, including mammalian target of rapamycin inhibitors, on graft survival is still discussed, and the effect on proteinuria is crucial to the debate. The fact that chronic allograft rejection may exist as early as 3 months after renal transplantation indicates that optimal management of low-grade proteinuria or microalbuminuria should occur very early after transplantation to improve long-term renal function and the overall outcome of renal transplant recipients. The presence of low-grade proteinuria or microalbuminuria early after transplantation must be taken into account to choose adequate immunosuppressive and antihypertensive medications. Limited information exists regarding the benefit of therapeutic interventions to reduce low-grade proteinuria or microalbuminuria. Whether renin angiotensin blockade results in optimal nephroprotection in patients with low-grade proteinuria or microalbuminuria is not proven, especially in the absence of chronic allograft nephropathy. Observational studies and randomized clinical trials yield conflicting results. Finally, randomized clinical trials are urgently needed.

  5. Yield and tillering response of super hybrid rice Liangyoupeijiu to tillage and establishment methods

    Institute of Scientific and Technical Information of China (English)

    M.A.Badshah; Naimei; Tu; Yingbin; Zou; M.Ibrahim; Ke; Wang

    2014-01-01

    Tillering is an important agronomic trait for rice grain production. To evaluate yield and tillering response, Liangyoupeijiu(super hybrid rice) was grown in Hunan, China during 2011–2012 under different methods of tillage(conventional and no-tillage system) and crop establishment methods(transplanting at a spacing of 20 cm × 20 cm with one seedling per hill and direct seeding at a seeding rate of 22.5 kg ha-1). Our results revealed that, at maximum tillering(Max.) and at maturity(MA) stages, direct seeding(DS) resulted in 22% more tillers than transplanting(TP) irrespective of tillage system. Tiller mortality reached a peak between panicle initiation(PI) and booting(BT) stages, and was 16% higher under conventional tillage(CT) than under no-tillage(NT). Transplanting required 29% more time for the completion of tillering and less for DS. Tillering rate was 43% higher in DS than TP under either CT or NT. There was a positive correlation between panicle number per m2and maximum tiller number per m2, but not panicle-bearing tiller rate. The panicle bearing tiller rate was higher under DS than TP and higher under NT than CT. Tiller dry weight gradually increased up to heading(HD) stage, and was 14% higher under TP than DS. Leaf area(cm2tiller-1) gradually increased from Max. to HD stage and then decreased by 34% in conventional tillage transplanting(CTTP) and 45% in no-tillage transplanting(NTTP) from 12DAH–24DAH(days after heading), but was similar(35%) under DS under either CT or NT. Grain yield was higher under CTTP owing to the larger sink size(heavier panicle, more spikelets in per cm length of panicle) than under DS.

  6. Contaminación acústica en el transporte sanitario urgente por carretera Acoustic contamination in urgent medical transportation by road

    Directory of Open Access Journals (Sweden)

    S. Ballesteros

    2012-12-01

    Full Text Available Fundamento. Determinar los niveles de exposición a ruido durante el transporte sanitario urgente por carretera y describir la percepción de deterioro de la función auditiva en los trabajadores del sector y el empleo de mecanismos de protección acústica. Metodología. Estudio observacional realizado en Bizkaia (España. Mediante dosimetrías sonométricas se registraron los valores instantáneos máximos de nivel sonoro (Lpico y niveles continuos equivalentes (Leq medidos en una ambulancia tipo de la red de emergencias. Paralelamente, se realizó una encuesta sobre una muestra representativa compuesta por 127 trabajadores en la que se exploró la percepción subjetiva de pérdida de audición y posibles factores asociados, además de otras cuestiones de interés desde la perspectiva de la prevención de riesgos laborales. Resultados. Se registraron Lpico oscilantes entre 80 y 109 dBA en función de la ubicación. Los niveles Leq medios evaluados durante 10 asistencias, desde la activación hasta la llegada al incidente y durante el traslado al hospital fueron de 79,5 dBA y 74,3 dBA (pBackground. To determine levels of exposure to noise during urgent medical transportation by road and to describe the perception of hearing function impairment in workers and the use of hearing protection devices. Material and methods. An observational study was performed in Bizkaia (Spain. The instantaneous maximum noise levels (Lpeak and its continuous equivalents (Leq were recorded through sonometric dosimetries, measured in a "sample ambulance" of the emergency network. In parallel, a survey was conducted on a representative sample of 127 workers in which self-reported hearing loss and associated factors were explored, in addition to other issues of concern from the perspective of prevention of occupational hazards. Results. Lpeak oscillating between 80 and 109 dBA were recorded depending on the location. The average Leq levels measured over 10 emergency

  7. KML Super Overlay to WMS Translator

    Science.gov (United States)

    Plesea, Lucian

    2007-01-01

    This translator is a server-based application that automatically generates KML super overlay configuration files required by Google Earth for map data access via the Open Geospatial Consortium WMS (Web Map Service) standard. The translator uses a set of URL parameters that mirror the WMS parameters as much as possible, and it also can generate a super overlay subdivision of any given area that is only loaded when needed, enabling very large areas of coverage at very high resolutions. It can make almost any dataset available as a WMS service visible and usable in any KML application, without the need to reformat the data.

  8. Super-resolution optical microscopy: multiple choices.

    Science.gov (United States)

    Huang, Bo

    2010-02-01

    The recent invention of super-resolution optical microscopy enables the visualization of fine features in biological samples with unprecedented clarity. It creates numerous opportunities in biology because vast amount of previously obscured subcellular processes now can be directly observed. Rapid development in this field in the past two years offers many imaging modalities that address different needs but they also complicates the choice of the 'perfect' method for answering a specific question. Here I will briefly describe the principles of super-resolution optical microscopy techniques and then focus on comparing their characteristics in various aspects of practical applications.

  9. Super resolution of images and video

    CERN Document Server

    Katsaggelos, Aggelos K

    2007-01-01

    This book focuses on the super resolution of images and video. The authors' use of the term super resolution (SR) is used to describe the process of obtaining a high resolution (HR) image, or a sequence of HR images, from a set of low resolution (LR) observations. This process has also been referred to in the literature as resolution enhancement (RE). SR has been applied primarily to spatial and temporal RE, but also to hyperspectral image enhancement. This book concentrates on motion based spatial RE, although the authors also describe motion free and hyperspectral image SR problems. Also exa

  10. Super-Laplacians and their symmetries

    Science.gov (United States)

    Howe, P. S.; Lindström, U.

    2017-05-01

    A super-Laplacian is a set of differential operators in superspace whose highestdimensional component is given by the spacetime Laplacian. Symmetries of super-Laplacians are given by linear differential operators of arbitrary finite degree and are determined by superconformal Killing tensors. We investigate these in flat superspaces. The differential operators determining the symmetries give rise to algebras which can be identified in many cases with the tensor algebras of the relevant superconformal Lie algebras modulo certain ideals. They have applications to Higher Spin theories.

  11. Organ Transplant Patients and Fungal Infections

    Science.gov (United States)

    ... M, Practice ASTIDCo. Endemic fungal infections in solid organ transplantation. American Journal of Transplantation 2013;13 Suppl 4: ... Michaels MG. Strategies for safe living after solid organ transplantation. American Journal of Transplantation 2013;13 Suppl 4: ...

  12. New method for making super-plastic glasses

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ It was a long-cherished dream for materials scientists to find a nearly ideal metallic alloy with high strength and super-plasticity concurrently as a super-material both extremely strong and exceptionally hard for human use.

  13. Second invariant for two-dimensional classical super systems

    Indian Academy of Sciences (India)

    S C Mishra; Roshan Lal; Veena Mishra

    2003-10-01

    Construction of superpotentials for two-dimensional classical super systems (for ≥ 2) is carried out. Some interesting potentials have been studied in their super form and also their integrability.

  14. LIVER TRANSPLANTATION AND HBV INFECTION

    Directory of Open Access Journals (Sweden)

    O. I. Andreytseva

    2009-01-01

    Full Text Available The paper describes the modern approaches in treatment of hepatitis B virus (HBV-infected patients who underwent liver transplantation. The patients with HBV liver cirrhosis and waiting for orthotopic liver transplantation (OLT have to receive long-term therapy with nucleos(tide analogs right up to liver transplantation. The paper discuss the different schemes of prophylaxis of recurrent HBV infection during post-transplantation and specific treatment of HBV infection after liver transplantation as well as possibilities of orthotopic liver transplantation for patients with liver cancer. 

  15. Single port laparoscopic colorectal surgery in debilitated patients and in the urgent setting.

    LENUS (Irish Health Repository)

    Moftah, M

    2012-09-01

    Single port laparoscopy is a relatively new niche in the expanding spectrum of minimal access surgery for colorectal disease. To date the published experience has predominantly focused on planned operations for neoplasia in the elective setting. It seems probable however that the benefits of minimal abdominal wounding will be greatest among those patients with the highest risk of impaired wound healing. Combining this with the impression of improved cosmesis suggests that (the mostly young) patients with inflammatory bowel disease needing urgent operation are the most likely to appreciate and benefit from the extraoperative effort. The extension of single port surgery to the acute setting and for debilitated individuals is therefore a likely next step advance in broadening the category of patients for whom it represents a real benefit and ultimately aid in focusing by selection the subgroups for whom this technique is best suited and most appropriate. We describe here our approach (including routine use of a surgical glove port) to patients presenting for urgent colorectal operation for benign disease. As provision of specialized approaches regardless of timing or mode of presentation is a defining component of any specialty service, this concept will soon be more fully elucidated and established.

  16. The carcinogenic effects of aspartame: The urgent need for regulatory re-evaluation.

    Science.gov (United States)

    Soffritti, Morando; Padovani, Michela; Tibaldi, Eva; Falcioni, Laura; Manservisi, Fabiana; Belpoggi, Fiorella

    2014-04-01

    Aspartame (APM) is an artificial sweetener used since the 1980s, now present in >6,000 products, including over 500 pharmaceuticals. Since its discovery in 1965, and its first approval by the US Food and Drugs Administration (FDA) in 1981, the safety of APM, and in particular its carcinogenicity potential, has been controversial. The present commentary reviews the adequacy of the design and conduct of carcinogenicity bioassays on rodents submitted by G.D. Searle, in the 1970s, to the FDA for market approval. We also review how experimental and epidemiological data on the carcinogenic risks of APM, that became available in 2005 motivated the European Commission (EC) to call the European Food and Safety Authority (EFSA) for urgent re-examination of the available scientific documentation (including the Searle studies). The EC has further requested that, if the results of the evaluation should suggest carcinogenicity, major changes must be made to the current APM specific regulations. Taken together, the studies performed by G.D. Searle in the 1970s and other chronic bioassays do not provide adequate scientific support for APM safety. In contrast, recent results of life-span carcinogenicity bioassays on rats and mice published in peer-reviewed journals, and a prospective epidemiological study, provide consistent evidence of APM's carcinogenic potential. On the basis of the evidence of the potential carcinogenic effects of APM herein reported, a re-evaluation of the current position of international regulatory agencies must be considered an urgent matter of public health.

  17. Diagnosis and management of acute otitis media in the urgent care setting.

    Science.gov (United States)

    McCracken, George H

    2002-04-01

    The prevalence of otitis media is increasing, which affects health care resource utilization across all segments, including the urgent care setting. One of the greatest challenges in the management of acute otitis media (AOM) is the effective treatment of cases caused by pathogens that are resistant to commonly used antibiotics. Whereas the production of beta-lactamases among strains of Haemophilus influenzae and Moraxella catarrhalis is an important consideration for antimicrobial therapy, the high prevalence of resistance to penicillin and other classes of antibiotics among strains of Streptococcus pneumoniae represents a greater clinical concern. The Centers for Disease Control and Prevention (CDC) recently convened the Drug Resistant S. pneumoniae Therapeutic Working Group to develop evidence-based recommendations for the treatment of AOM in an era of prevalent resistance. The recommendations from this group included amoxicillin as the preferred first-line drug because of the demonstrated activity against penicillin-intermediate and -resistant strains of S. pneumoniae, using higher dosages of up to 90 mg/kg per day in certain settings. For patients in whom initial treatment is unsuccessful after 3 days, the recommended agents included high-dose amoxicillin-clavulanate (for activity against beta-lactamase-producing pathogens), clindamycin, cefuroxime axetil, or 1 to 3 doses of intramuscular ceftriaxone. The principles set forth in these guidelines can assist the therapeutic decisionmaking process for practitioners in the urgent care setting.

  18. Refusing HIV testing in an urgent care setting: results from the "Think HIV" program.

    Science.gov (United States)

    Liddicoat, Rebecca V; Losina, Elena; Kang, Minhee; Freedberg, Kenneth A; Walensky, Rochelle P

    2006-02-01

    Efforts to increase HIV case identification through routine, voluntary HIV testing are hindered by high refusal rates. Our objective was to identify patients most likely to refuse routine HIV testing. We developed a new HIV testing program at four Massachusetts urgent care centers. Patients were asked if they were interested in routine HIV testing. We performed analyses to assess differences in characteristics between those who refused testing and those who accepted it. Data were available for 9129/10,354 (88%) patients offered routine HIV testing from January to December 2002. Of these 9129 patients, 67% refused testing. In the crude analysis, HIV test refusal was associated with female gender, white race, older age, and higher educational level. In multivariate analysis, non-English-speaking patients who were Hispanic, Haitian, and other race were more likely to refuse testing than their English-speaking counterparts. Among all patients, "not at risk" and "already tested" were the most common reasons for test refusal. Two thirds of patients refused routine HIV testing when it was offered in a statewide urgent care-based program. If routine HIV testing programs are to be successful, strategies must be developed to increase HIV test acceptance among patients most likely to refrain from testing.

  19. Urgent Biophilia: Human-Nature Interactions and Biological Attractions in Disaster Resilience

    Directory of Open Access Journals (Sweden)

    Keith G. Tidball

    2012-06-01

    Full Text Available This contribution builds upon contemporary work on principles of biological attraction as well as earlier work on biophilia while synthesizing literatures on restorative environments, community-based ecological restoration, and both community and social-ecological disaster resilience. It suggests that when humans, faced with a disaster, as individuals and as communities and populations, seek engagement with nature to further their efforts to summon and demonstrate resilience in the face of a crisis, they exemplify an urgent biophilia. This urgent biophilia represents an important set of human-nature interactions in SES characterized by hazard, disaster, or vulnerability, often appearing in the 'backloop' of the adaptive cycle. The relationships that human-nature interactions have to other components within interdependent systems at many different scales may be one critical source of resilience in disaster and related contexts. In other words, the affinity we humans have for the rest of nature, the process of remembering that attraction, and the urge to express it through creation of restorative environments, which may also restore or increase ecological function, may confer resilience across multiple scales. In making this argument, the paper also represents a novel contribution to further theorizing alternatives to anthropocentric understandings of human-nature relations, and strongly makes the case for humans as part of, not separate from, ecosystems.

  20. [Monitoring of intra-abdominal pressure and abdominal perfusion pressure in urgent abdominal surgery].

    Science.gov (United States)

    Raĭbuzhis, E N; Fot, E V; Gaĭdukov, K M; Kirov, M Iu

    2014-01-01

    To evaluate the changes in intra-abdominal pressure (IAP) and abdominal perfusion pressure (APP) during perioperative period in urgent abdominal surgery and to assess the relationship of these parameters with gas exchange and tissue perfusion. Twenty-four patients undergoing emergency abdominal surgery were enrolled into a prospective observational study. We recorded IAP APP, mean arterial pressure, arterial and venous blood gases after induction of anesthesia, at the end of surgery, and 6, 12, 48 and 72 h postoperatively. LAP was measured by nasogastric tube using CiMON monitor (Pulsion Medical Systems, Germany). In addition, we studied the relationship of IAP and APP with blood gases parameters. We observed perioperative increase of IAP (> 12 mm Hg) in 75% of enrolled patients, tendency to postoperative rise of IAP and transient increase of arterial lactate at 6 h after surgery. APP remained within normal values. We found positive correlation of APP with PaO2/FiO2 and ScvO2 at 72 hours after surgery. Transient perioperative increase of IAP was observed in 75% patients undergoing urgent abdominal surgery; however in parallel with intensive care the abdominal perfusion pressure remained within normal values. Abdominal perfusion is related with arterial oxygenation and central venous saturation.

  1. Urgent Coronary Artery Bypass Surgery in a Patient with Postinfarction Angina and Active Myelomonocytic Leukaemia

    Directory of Open Access Journals (Sweden)

    Samuel Anthony Galea

    2016-11-01

    Full Text Available Chronic myelomonocytic leukaemia (CMML is a myelodysplastic/myeloproliferative neoplasm affecting the production and differentiation of the monocyte cell lineage. Cardiac surgery in the context of CMML poses challenges that are not routinely encountered. This is the first reported case in the literature of a patient with active CMML undergoing urgent on-pump coronary artery bypass grafting. A 68-year-old Caucasian man with a history of hypertension, hyperlipidaemia, hypothyroidism, and hypercholesterolaemia, who had been diagnosed by the haematologists with CMML a few months earlier but had remained untreated, underwent urgent surgical coronary revascularisation because of postinfarction angina following a non-ST elevation myocardial infarction associated with troponin I rise. The patient had fulminant postoperative myelomonocytic leukaemoid reaction, with a clinical picture of severe systemic inflammatory response syndrome and multiple organ dysfunction syndrome. This led to extensive vasodilation and heart failure that resulted in the death of the patient. Various authors have suggested different techniques and treatment options, each attempting to mitigate the effect of the postoperative inflammatory response. However, this is a high-risk endeavour with a myriad of inflammatory signals mobilised into action because of the surgical insult. Off-pump surgery or preoperative pharmacological attenuation of CMML activity might have dampened this response and resulted in a positive outcome for the patient.

  2. Use of the emergency department for less-urgent care among type 2 diabetics under a disease management program

    Directory of Open Access Journals (Sweden)

    Myers Leann

    2009-12-01

    Full Text Available Abstract Background This study analyzed the likelihood of less-urgent emergency department (ED visits among type 2 diabetic patients receiving care under a diabetes disease management (DM program offered by the Louisiana State University Health Care Services Division (LSU HCSD. Methods All ED and outpatient clinic visits made by 6,412 type 2 diabetic patients from 1999 to 2006 were extracted from the LSU HCSD Disease Management (DM Evaluation Database. Patient ED visits were classified as either urgent or less-urgent, and the likelihood of a less-urgent ED visit was compared with outpatient clinic visits using the Generalized Estimating Equation methodology for binary response to time-dependent variables. Results Patients who adhered to regular clinic visit schedules dictated by the DM program were less likely to use the ED for less urgent care with odds ratio of 0.1585. Insured patients had 1.13 to 1.70 greater odds of a less-urgent ED visit than those who were uninsured. Patients with better-managed glycated hemoglobin (A1c or HbA1c levels were 82 times less likely to use less-urgent ED visits. Furthermore, being older, Caucasian, or a longer participant in the DM program had a modestly lower likelihood of less-urgent ED visits. The patient's Charlson Comorbidity Index (CCI, gender, prior hospitalization, and the admitting facility showed no effect. Conclusion Patients adhering to the DM visit guidelines were less likely to use the ED for less-urgent problems. Maintaining normal A1c levels for their diabetes also has the positive impact to reduce less-urgent ED usages. It suggests that successful DM programs may reduce inappropriate ED use. In contrast to expectations, uninsured patients were less likely to use the ED for less-urgent care. Patients in the DM program with Medicaid coverage were 1.3 times more likely to seek care in the ED for non-emergencies while commercially insured patients were nearly 1.7 times more likely to do so. Further

  3. An integrable generalization of the super AKNS hierarchy and its bi-Hamiltonian formulation

    Science.gov (United States)

    Yu, Jing; Ma, Wen-Xiu; Han, Jingwei; Chen, Shouting

    2017-02-01

    Based on a Lie super-algebra B(0, 1), an integrable generalization of the super AKNS iso-spectral problem is introduced and its corresponding generalized super AKNS hierarchy is generated. By making use of the super-trace identity (or the super variational identity), the resulting super soliton hierarchy can be put into a super bi-Hamiltonian form. A generalized super AKNS soliton hierarchy with self-consistent sources is also presented.

  4. Explosive Super-eruptions: Problems and Prejudices

    Science.gov (United States)

    Self, S.

    2010-12-01

    A super-eruption is defined as one with a magma yield > 10^15 kg (magnitude (M) 8). The term has mainly been applied to large-scale, caldera and ignimbrite-forming explosive eruptions, but it can be applied to all eruptions that released > 10^15 kg of magma. For effusive volcanism, evidence suggests that individual eruptions of this size ( > ~ 370 km^3 of typical basalt or > 450 km^3 of rhyolite flood lava) arise only during periods of LIP formation. The super-eruption concept raises interesting questions about genesis and storage of magmas that feed these vast events. Deposits of major explosive eruptions are Plinian fallout, ignimbrite sheets, and co-ignimbrite ash fall. Based on earlier suggestions and evidence, widespread outflow ignimbrite (O), co-ignimbrite ash (A), and inter-caldera ignimbrite (I) are all major components of the total super-eruption deposit and may tend towards being subequal. In super-eruption deposits, the reported volume of vent-derived Plinian eruption column fallout is often a minor component of the total volume, yet in several cases (Oruanui, Taupo, 26 ka ago, M 8.1; Bishop Tuff, 760 ka, M 8.2; Bandelier (Otowi) Tuff, 1.6 Ma, M8) it is now recognized that vent-derived columns persisted for most of the eruption. Thus, distally, the ash-fall derived from co-ignimbrite ash clouds may be mixed with contemporaneous fallout from a vertical column. Some major ignimbrites have no reported associated Plinian deposit; the huge Young Toba Tuff (YTT, 74 ka, M 8.8) is a significant example. However, the very widespread Toba ash-fall deposit constitutes ~ 40 % of the total mass of magma erupted and is presumed to be co-ignimbrite. Timing of the onset of column collapse probably controls whether a recognizable Plinian deposit is laid down. All super-eruptions probably produce extensive fallout deposits, and this is generally of vent-derived and pyroclastic-flow-derived origin. Establishing the relationships between large-scale ignimbrites and their

  5. On super edge-graceful trees of diameter four

    CERN Document Server

    Krop, E; Raridan, C

    2011-01-01

    In "On the super edge graceful trees of even orders," Chung, Lee, Gao, and Schaffer posed the following problem: Characterize trees of diameter 4 which are super edge-graceful. In this paper, we provide super edge-graceful labelings for all caterpillars and even size lobsters of diameter 4 which permit such labelings. We also provide super edge-graceful labelings for several families of odd size lobsters of diameter 4.

  6. European Transplant Registry of Senior Renal Transplant Recipients on Advagraf

    Science.gov (United States)

    2016-08-11

    Graft Failure; Death; Acute Rejection of Renal Transplant; Infections; Bone Disease; Post Transplant Diabetes Mellitus; Quality of Life; HLA Antibody Production; Cardiovascular Risk Factors; Non-HLA Antibody Production

  7. Liver transplantation in Germany.

    Science.gov (United States)

    Tacke, Frank; Kroy, Daniela C; Barreiros, Ana Paula; Neumann, Ulf P

    2016-08-01

    Liver transplantation (LT) is a well-accepted procedure for end-stage liver disease in Germany. In 2015, 1489 patients were admitted to the waiting list (including 1308 new admissions), with the leading etiologies being fibrosis and cirrhosis (n = 349), alcoholic liver disease (n = 302), and hepatobiliary malignancies (n = 220). Organ allocation in Germany is regulated within the Eurotransplant system based on urgency as expressed by the Model for End-Stage Liver Disease score. In 2015, only 894 LTs (n = 48 from living donors) were performed at 23 German transplant centers, reflecting a shortage of organs. Several factors may contribute to the low number of organ donations. The German transplant legislation only accepts donation after brain death (not cardiac death), whereas advances in neurosurgery and a more frequently requested "palliative care" approach render fewer patients suitable as potential donors. The legislation further requires the active consent of the donor or first-degree relatives before donation. Ongoing debates within the German transplant field address the optimal management of patients with alcoholic liver cirrhosis, hepatocellular carcinoma (HCC), and cholangiocarcinoma and measures to increase living donor transplantations. As a result of irregularities at mainly 4 German transplant centers that were exposed in 2012, guiding principles updated by the German authorities have since implemented strict rules (including internal and external auditing, the 8-eyes principle, mandatory repeated testing for alcohol consumption) to prohibit any manipulations in organ allocation. In conclusion, we will summarize important aspects on the management of LT in Germany, discuss legal and organizational aspects, and highlight challenges mainly related to the relative lack of organ donations, increasing numbers of extended criteria donors, and the peculiarities of the recipient patients. Liver Transplantation 22 1136-1142 2016 AASLD.

  8. Growth and development characteristics of super-high-yielding mid-season japonica rice

    Institute of Scientific and Technical Information of China (English)

    YANG Jianchang; DU Yong; WU Changfu; LIU Lijun; WANG Zhiqin; ZHU Qingsen

    2007-01-01

    Rice is one of the most important food crops in China.The realization of the super-high-yielding (SHY)type has great significance in ensuring food security in this country.This study investigated the growth and development characteristics of the super-high-yielding rice (grain yield>11 t/hm2).Four mid-season japonica rice cultivars (including lines):Lianjiajing 2,Huajing 5,0026 and 9823,were grown in the paddy field.Growth analysis was performed during the growth period,and yield components were determined at maturity.Results showed that SHY rice had more sipkelets per panicle and higher filled-grain percentage than the high-yielding rice (CK,grain yield 8.98-9.16 t/hm2).There was no significant difference in the 1 000-grain weight between the super-high-yielding and the CK.Super-high-yield rice exhib ited fewer tillers at the early growth stage (from transplanting to jointing),with a higher ratio of productive tillers to total tillers,when compared with the CK.The leaf area index (LAI),photosynthetic potential and dry matter accumulation were lower for the SHY rice than those for the CK at the early growth stage,and the differences were not significant between the two rice types at heading,but were greater in the former than the latter after heading.The root-shoot ratio at each growth stage,root bleedings from heading to maturity,grain-leaf ratio,translocation percentage of the matter from stems and sheaths and harvest index of super-high-yielding rice were greater than those of CK.The indexes for the growth and development of SHY mid-season rice population were suggested,i.e.total spikelets>4.5×104/m2,filled-grain percentage>90%,1 000-grain weight>26 g;ratio of productive tillers>80%,leaf area index at heading 7.5-8.0,photosynthetic potential during the whole growth period >22 t/hm2,harvest index>0.51;grain-leaf ratio (number of spikelets per cm2 leaf area)>0.58;root-shoot ratio at heading tion approaches and key cultivation techniques for raising the

  9. The structure of the super-W∞(λ) algebra

    NARCIS (Netherlands)

    Bergshoeff, E.; Wit, B. de; Vasiliev, M.

    1991-01-01

    We give a comprehensive treatment of the super-W∞(λ) algebra, an extension of the super-Virasoro algebra that contains generators of spin s ≥ ½. The parameter λ defines the embedding of the Virasoro subalgebra. We describe how to obtain the super-W∞(λ) algebra from the associative algebra of

  10. Public Health Surveillance Strategies for Mass Gatherings: Super Bowl XLIX and Related Events, Maricopa County, Arizona, 2015.

    Science.gov (United States)

    Ayala, Aurimar; Berisha, Vjollca; Goodin, Kate; Pogreba-Brown, Kristen; Levy, Craig; McKinney, Benita; Koski, Lia; Imholte, Sara

    2016-01-01

    Super Bowl XLIX took place on February 1, 2015, in Glendale, Arizona. In preparation for this event and associated activities, the Maricopa County Department of Public Health (MCDPH) developed methods for enhanced surveillance, situational awareness, and early detection of public health emergencies. Surveillance strategies implemented from January 22 to February 6, 2015, included enhanced surveillance alerts; animal disease surveillance; review of NFL clinic visits; syndromic surveillance for emergency room visits, urgent care facilities, and hotels; real-time onsite syndromic surveillance; all-hazards mortality surveillance; emergency medical services surveillance, review of poison control center reports; media surveillance; and aberration detection algorithms for notifiable diseases. Surveillance results included increased influenzalike illness activity reported from urgent care centers and a few influenza cases reported in the NFL clinic. A cyanide single event exposure was investigated and determined not to be a public health threat. Real-time field syndromic surveillance documented minor injuries at all events and sporadic cases of gastrointestinal and neurological (mostly headaches) disease. Animal surveillance reports included a cat suspected of carrying plague and tularemia and an investigation of highly pathogenic avian influenza in a backyard chicken flock. Laboratory results in both instances were negative. Aberration detection and syndromic surveillance detected an increase in measles reports associated with a Disneyland exposure, and syndromic surveillance was used successfully during this investigation. Coordinated enhanced epidemiologic surveillance during Super Bowl XLIX increased the response capacity and preparedness of MCDPH to make informed decisions and take public health actions in a timely manner during these mass gathering events.

  11. Super ready: how a regional approach to Super Bowl EMS paid off.

    Science.gov (United States)

    Clancy, Terry; Cortacans, Henry P

    2014-07-01

    The Super Bowl and its associated activities represent one of the largest special events in the world. Super Bowl XLVIII was geographically unique because the NFL's and Super Bowl Host Committee's activities, venues and events encompassed two states and fell across numerous jurisdictions within six counties (Bergen, Hudson, Morris, Essex, Middlesex, and Manhattan).This Super Bowl was the first to do this. EMS was one of the largest operational components during this event. Last and most important, it is the people and relationships that make any planning initiative and event a success. Sit down and have a cup a coffee with your colleagues, partners and neighbors in and out of state to discuss your planning initiatives. Do it early-it will make your efforts less painful should an event of this magnitude come to a city near you!

  12. Acoustic Design of Super-light Structures

    DEFF Research Database (Denmark)

    Christensen, Jacob Ellehauge; Hertz, Kristian Dahl; Brunskog, Jonas

    aggregate (leca) along with a newly developed technology called pearl-chain reinforcement, which is a system for post-tensioning. Here, it is shown how to combine these technologies within a precast super-light slab element, while honoring the requirements of a holistic design. Acoustic experiments...

  13. Folded shapes with Super-Light Structures

    DEFF Research Database (Denmark)

    Castberg, Niels Andreas; Hertz, Kristian Dahl

    2012-01-01

    The use of folded shapes in structures has become more common, but it still costs problems because of construction issues and bending moments. The present paper deals with how the newly patented structural concept Super-Light structures (SLS) can be used to create folded shapes. SLS gives lighter...

  14. Single Image Super Resolution via Sparse Reconstruction

    NARCIS (Netherlands)

    Kruithof, M.C.; Eekeren, A.W.M. van; Dijk, J.; Schutte, K.

    2012-01-01

    High resolution sensors are required for recognition purposes. Low resolution sensors, however, are still widely used. Software can be used to increase the resolution of such sensors. One way of increasing the resolution of the images produced is using multi-frame super resolution algorithms. Limita

  15. Conformal anomaly of super Wilson loop

    Energy Technology Data Exchange (ETDEWEB)

    Belitsky, A.V., E-mail: andrei.belitsky@asu.edu [Department of Physics, Arizona State University, Tempe, AZ 85287-1504 (United States)

    2012-09-11

    Classically supersymmetric Wilson loop on a null polygonal contour possesses all symmetries required to match it onto non-MHV amplitudes in maximally supersymmetric Yang-Mills theory. However, to define it quantum mechanically, one is forced to regularize it since perturbative loop diagrams are not well defined due to presence of ultraviolet divergences stemming from integration in the vicinity of the cusps. A regularization that is adopted by practitioners by allowing one to use spinor helicity formalism, on the one hand, and systematically go to higher orders of perturbation theory is based on a version of dimensional regularization, known as Four-Dimensional Helicity scheme. Recently it was demonstrated that its use for the super Wilson loop at one loop breaks both conformal symmetry and Poincare supersymmetry. Presently, we exhibit the origin for these effects and demonstrate how one can undo this breaking. The phenomenon is alike the one emerging in renormalization group mixing of conformal operators in conformal theories when one uses dimensional regularization. The rotation matrix to the diagonal basis is found by means of computing the anomaly in the Ward identity for the conformal boost. Presently, we apply this ideology to the super Wilson loop. We compute the one-loop conformal anomaly for the super Wilson loop and find that the anomaly depends on its Grassmann coordinates. By subtracting this anomalous contribution from the super Wilson loop we restore its interpretation as a dual description for reduced non-MHV amplitudes which are expressed in terms of superconformal invariants.

  16. Super-Kamiokande worth full restoration

    CERN Multimedia

    Mishima, I

    2002-01-01

    While prospects are good that the SuperKamiokande facility will be partially repaired after an accident last November, the government has yet to confirm whether it will spend the estimated 2.5 billion yen needed for a full-scale restoration (1 page).

  17. Structural optimization of super-repellent surfaces

    DEFF Research Database (Denmark)

    Cavalli, Andrea; Bøggild, Peter; Okkels, Fridolin

    2013-01-01

    Micro-patterning is an effective way to achieve surfaces with extreme liquid repellency. This technique does not rely on chemical coatings and is therefore a promising concept for application in food processing and bio-compatibile coatings. This super-repellent behaviour is obtained by suspending...

  18. Facile preparation of super durable superhydrophobic materials.

    Science.gov (United States)

    Wu, Lei; Zhang, Junping; Li, Bucheng; Fan, Ling; Li, Lingxiao; Wang, Aiqin

    2014-10-15

    The low stability, complicated and expensive fabrication procedures seriously hinder practical applications of superhydrophobic materials. Here we report an extremely simple method for preparing super durable superhydrophobic materials, e.g., textiles and sponges, by dip coating in fluoropolymers (FPs). The morphology, surface chemical composition, mechanical, chemical and environmental stabilities of the superhydrophobic textiles were investigated. The results show how simple the preparation of super durable superhydrophobic textiles can be! The superhydrophobic textiles outperform their natural counterparts and most of the state-of-the-art synthetic superhydrophobic materials in stability. The intensive mechanical abrasion, long time immersion in various liquids and repeated washing have no obvious influence on the superhydrophobicity. Water drops are spherical in shape on the samples and could easily roll off after these harsh stability tests. In addition, this simple dip coating approach is applicable to various synthetic and natural textiles and can be easily scaled up. Furthermore, the results prove that a two-tier roughness is helpful but not essential with regard to the creation of super durable superhydrophobic textiles. The combination of microscale roughness of textiles and materials with very low surface tension is enough to form super durable superhydrophobic textiles. According to the same procedure, superhydrophobic polyurethane sponges can be prepared, which show high oil absorbency, oil/water separation efficiency and stability. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Pavement behaviour under the super single tyre

    CSIR Research Space (South Africa)

    Viljoen, AW

    1982-06-01

    Full Text Available Pavement behaviour under the super single tyre (SST) was investigated and compared with that under a conventional dual tyre (CDT). Contact areas and contact pressures over a range of loading conditions were measured and compared. Two approaches were...

  20. Typhoon effects on super-tall buildings

    Science.gov (United States)

    Li, Q. S.; Xiao, Y. Q.; Wu, J. R.; Fu, J. Y.; Li, Z. N.

    2008-06-01

    Full-scale measurement is considered to be the most reliable method for evaluating wind effects on buildings and structures. This paper presents selected results of wind characteristics and structural responses measured from four super-tall buildings, The Center (350 m high, 79 floors) in Hong Kong, Di Wang Tower (384 m high, 78 floors) in Shenzhen, CITIC Plaza Tower (391 m high, 80 floors) in Guangzhou and Jin Mao Building (421 m high, 88 floors) in Shanghai, during the passages of three typhoons. The field data such as wind speed, wind direction and acceleration responses, etc., were continuously measured from the super-tall buildings during the typhoons. Detailed analysis of the field data was conducted to investigate the characteristics of typhoon-generated wind and wind-induced vibrations of these super-tall buildings under typhoon conditions. The dynamic characteristics of the tall buildings were determined from the field measurements and comparisons with those calculated from the finite element (FE) models of the structures were made. Furthermore, the full-scale measurements were compared with wind tunnel results to evaluate the accuracy of the model test results and the adequacy of the techniques used in the wind tunnel tests. The results presented in this paper are expected to be of considerable interest and of use to researchers and professionals involved in designing super-tall buildings.

  1. Searching for Frozen Super Earth via Microlensing

    Science.gov (United States)

    Batista, V.; Beaulieu, J. P.; Cassan, A.; Coutures, C.; Donatowicz, J.; Fouqué, P.; Kubas, D.; Marquette, J. B.

    2009-04-01

    Microlensing planet hunt is a unique method to probe efficiently for frozen Super Earth orbiting the most common stars of our galaxy. It is nicely complementing the parameter space probed by very high accuracy radial velocity measurements and future space based detections of low mass transiting planets. In order to maximize the planet catch, the microlensing community is engaged in a total cooperation among the different groups (OGLE, MicroFUN, MOA, PLANET/RoboNET) by making the real time data available, and mutual informing/reporting about modeling efforts. Eight planets have been published so far by combinations of the different groups, 4 Jovian analogues, one Neptune and two Super Earth. Given the microlensing detection efficiency, it suggests that these Neptunes/Super Earths may be quite common. Using networks of dedicated 1-2m class telescopes, the microlensing community has entered a new phase of planet discoveries, and will be able to provide constraints on the abundance of frozen Super-Earths in the near future. Statistics about Mars to Earth mass planets, extending to the habitable zone will be achieved with space based wide field imagers (EUCLID) at the horizon 2017.

  2. Folded shapes with Super-Light Structures

    DEFF Research Database (Denmark)

    Castberg, Niels Andreas; Hertz, Kristian Dahl

    2012-01-01

    The use of folded shapes in structures has become more common, but it still costs problems because of construction issues and bending moments. The present paper deals with how the newly patented structural concept Super-Light structures (SLS) can be used to create folded shapes. SLS gives lighter...

  3. Advantages of super-light structures

    DEFF Research Database (Denmark)

    Hertz, Kristian Dahl

    2009-01-01

    Super-light structures with pearl-chain reinforcement is a new revolutionary technology that opens possibilities of building load-bearing structures much cheaper and with several other advantages compared to traditional constructions of concrete and steel. Some benefits are: 1 Half price or less. 2...

  4. Super-resolution near field imaging device

    DEFF Research Database (Denmark)

    2014-01-01

    Super-resolution imaging device comprising at least a first and a second elongated coupling element, each having a first transverse dimension at a first end and a second transverse dimension at a second end and being adapted for guiding light between their respective first and second ends, each...

  5. Predicting Alloreactivity in Transplantation

    Directory of Open Access Journals (Sweden)

    Kirsten Geneugelijk

    2014-01-01

    Full Text Available Human leukocyte Antigen (HLA mismatching leads to severe complications after solid-organ transplantation and hematopoietic stem-cell transplantation. The alloreactive responses underlying the posttransplantation complications include both direct recognition of allogeneic HLA by HLA-specific alloantibodies and T cells and indirect T-cell recognition. However, the immunogenicity of HLA mismatches is highly variable; some HLA mismatches lead to severe clinical B-cell- and T-cell-mediated alloreactivity, whereas others are well tolerated. Definition of the permissibility of HLA mismatches prior to transplantation allows selection of donor-recipient combinations that will have a reduced chance to develop deleterious host-versus-graft responses after solid-organ transplantation and graft-versus-host responses after hematopoietic stem-cell transplantation. Therefore, several methods have been developed to predict permissible HLA-mismatch combinations. In this review we aim to give a comprehensive overview about the current knowledge regarding HLA-directed alloreactivity and several developed in vitro and in silico tools that aim to predict direct and indirect alloreactivity.

  6. Everolimus in kidney transplantation

    Directory of Open Access Journals (Sweden)

    Cooper JE

    2011-07-01

    Full Text Available James E Cooper¹, Uwe Christians², Alexander C Wiseman¹¹Division of Renal Diseases and Hypertension, Transplant Center, ²iC42 Integrated Solutions in Systems Biology for Clinical Research and Development, University of Colorado Denver, Aurora, CO, USAAbstract: Everolimus is a novel target of rapamycin (mTOR-I analog that has recently been approved in combination with cyclosporine A and steroids for use in the prevention of organ rejection in kidney transplant recipients. Compared with rapamycin, everolimus is characterized by a shorter half-life and improved bioavailability. Prior to US Food and Drug Administration approval, a number of Phase II and III clinical trials were undertaken to evaluate the effectiveness of everolimus in combination with calcineurin inhibitors for preventing acute rejection and promoting allograft survival in kidney transplant recipients. In this report, we review the pharmacokinetic properties of everolimus, the clinical efficacy studies that led to its approval for use in kidney transplantation, as well as reported data on patient safety and tolerability associated with its use.Keywords: mTOR inhibitors, kidney transplantation, everolimus

  7. BREEDING SUPER-EARTHS AND BIRTHING SUPER-PUFFS IN TRANSITIONAL DISKS

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eve J.; Chiang, Eugene, E-mail: evelee@berkeley.edu, E-mail: echiang@astro.berkeley.edu [Department of Astronomy, University of California Berkeley, Berkeley, CA 94720-3411 (United States)

    2016-02-01

    The riddle posed by super-Earths (1–4R{sub ⊕}, 2–20M{sub ⊕}) is that they are not Jupiters: their core masses are large enough to trigger runaway gas accretion, yet somehow super-Earths accreted atmospheres that weigh only a few percent of their total mass. We show that this puzzle is solved if super-Earths formed late, as the last vestiges of their parent gas disks were about to clear. This scenario would seem to present fine-tuning problems, but we show that there are none. Ambient gas densities can span many (in one case up to 9) orders of magnitude, and super-Earths can still robustly emerge after ∼0.1–1 Myr with percent-by-weight atmospheres. Super-Earth cores are naturally bred in gas-poor environments where gas dynamical friction has weakened sufficiently to allow constituent protocores to gravitationally stir one another and merge. So little gas is present at the time of core assembly that cores hardly migrate by disk torques: formation of super-Earths can be in situ. The basic picture—that close-in super-Earths form in a gas-poor (but not gas-empty) inner disk, fed continuously by gas that bleeds inward from a more massive outer disk—recalls the largely evacuated but still accreting inner cavities of transitional protoplanetary disks. We also address the inverse problem presented by super-puffs: an uncommon class of short-period planets seemingly too voluminous for their small masses (4–10R{sub ⊕}, 2–6M{sub ⊕}). Super-puffs most easily acquire their thick atmospheres as dust-free, rapidly cooling worlds outside ∼1 AU where nebular gas is colder, less dense, and therefore less opaque. Unlike super-Earths, which can form in situ, super-puffs probably migrated in to their current orbits; they are expected to form the outer links of mean-motion resonant chains, and to exhibit greater water content. We close by confronting observations and itemizing remaining questions.

  8. Urgent Care Facilities, DPH, Published in 2007, 1:24000 (1in=2000ft) scale, Massachusetts Emergency Managment Agency.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Urgent Care Facilities dataset, published at 1:24000 (1in=2000ft) scale, was produced all or in part from Orthoimagery information as of 2007. It is described...

  9. 76 FR 35719 - Unexpected Urgent Refugee and Migration Needs Related to Libya and C[ocirc]te d'Ivoire

    Science.gov (United States)

    2011-06-20

    ... Determination No. 2011-11 of June 8, 2011 Unexpected Urgent Refugee and Migration Needs Related to Libya and C... to the humanitarian crises resulting from the violence in Libya and C[ocirc]te d'Ivoire. You...

  10. 76 FR 53913 - Award of an Urgent Single-Source Grant to Survivors of Torture International (SOTI) in San Diego...

    Science.gov (United States)

    2011-08-30

    ... Torture International (SOTI) in San Diego, CA; Correction AGENCY: Office of Refugee Resettlement, ACF, HHS... urgent single-source grant to Survivors of Torture, International (SOTI), San Diego, CA. The document...

  11. PERIOPERATIVE PERIOD FOLLOWING HEART TRANSPLANTATION WITH SEVERE LEFT VENTRICULAR HYPERTROPHY

    Directory of Open Access Journals (Sweden)

    V. N. Poptsov

    2012-01-01

    Full Text Available Use donor hearts with left ventricular hypertrophy (LVH is controversial. This category of heart recipients has increasing risk of early graft failure. We proposed that heart transplantation (HT with LVH ≥1.5 cm may be successful if performed in selective category patients from alternate transplant list. This study included 10 pati- ents (2 female and 8 male at the age 26–62 (44 ± 3, who needed urgent HT. This study showed that recipients with LVH ≥1.5 cm demanded more high and long inotropic support with adrenalin and dopamine, more fre- quent use of levosimendan infusion (in 40% of cases and intraaortic balloon conterpulsation (in 50% of cases. However we didn’t observed any difference in survival rate (90.0% vs 89.0% and ICU time (4.8 ± 0.6 days vs 4.1 ± 0.4 days between HT recipients with and without LVH. Our study showed that HT from donor with LVH ≥1.5 cm may be performed in patients, demanding urgent HT, with acceptable early posttransplant results. 

  12. Organ Procurement and Transplantation Network

    Science.gov (United States)

    ... organs available for transplant. View all news articles Organ Procurement & Transplantation Network U.S. Department of Health and Human Services ... Publications Privacy Policy Questions? Contact Organ Procurement and ... Network for Organ Sharing Post Office Box 2484 Richmond, Virginia 23218 ...

  13. Organ Transplantation: Frequently Asked Questions

    Science.gov (United States)

    ... that can help patients afford the cost of transplantation? Organ matching and allocation What factors are considered in ... long will I have to wait? What is organ transplantation? If you have a medical condition that may ...

  14. Stem Cell Transplants (For Teens)

    Science.gov (United States)

    ... Can I Help Someone Who's Being Bullied? Volunteering Stem Cell Transplants KidsHealth > For Teens > Stem Cell Transplants Print ... Does it Take to Recover? Coping What Are Stem Cells? As you probably remember from biology class, every ...

  15. Muskox transplant report FY-80

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Status of transplant operations presented. A muskox- transplant to traditional range areas in the state was contemplated however several problems caused it to be...

  16. U.S. Transplantation Data

    Science.gov (United States)

    ... View the latest data about the status of U.S. organ donation and transplantation by UNOS region of ... View the latest data about the status of U.S. organ donation and transplantation by state of center. ...

  17. About the Operation: Heart Transplant

    Science.gov (United States)

    ... There are two very different surgical approaches to heart transplantation: the orthotopic and the heterotopic approach. Because the ... begins. Heterotopic Approach. Heterotopic transplantation, also called ... by leaving the recipient's heart in place and connecting the donor heart to ...

  18. SuperB A High-Luminosity Asymmetric $e^+ e^-$ Super Flavour Factory : Conceptual Design Report

    CERN Document Server

    Bona, M.; Grauges Pous, E.; Colangelo, P.; De Fazio, F.; Palano, A.; Manghisoni, M.; Re, V.; Traversi, G.; Eigen, G.; Venturini, M.; Soni, N.; Bruschi, M.; De Castro, S.; Faccioli, P.; Gabrieli, A.; Giacobbe, B.; Semprini Cesare, N.; Spighi, R.; Villa, M.; Zoccoli, A.; Hearty, C.; McKenna, J.; Soni, A.; Khan, A.; Barniakov, A.Y.; Barniakov, M.Y.; Blinov, V.E.; Druzhinin, V.P.; Golubev, V.B.; Kononov, S.A.; Koop, I.A.; Kravchenko, E.A.; Levichev, E.B.; Nikitin, S.A.; Onuchin, A.P.; Piminov, P.A.; Serednyakov, S.I.; Shatilov, D.N.; Skovpen, Y.I.; Solodov, E.A.; Cheng, C.H.; Echenard, B.; Fang, F.; Hitlin, D.J.; Porter, F.C.; Asner, D.M.; Pham, T.N.; Fleischer, R.; Giudice, G.F.; Hurth, T.; Mangano, M.; Mancinelli, G.; Meadows, B.T.; Schwartz, A.J.; Sokoloff, M.D.; Soffer, A.; Beard, C.D.; Haas, T.; Mankel, R.; Hiller, G.; Ball, P.; Pappagallo, M.; Pennington, M.R.; Gradl, W.; Playfer, S.; Abada, A.; Becirevic, D.; Descotes-Genon, S.; Pene, O.; Andreotti, D.; Andreotti, M.; Bettoni, D.; Bozzi, C.; Calabresi, R.; Cecchi, A.; Cibinetto, G.; Franchini, P.; Luppi, E.; Negrini, M.; Petrella, A.; Piemontese, L.; Prencipe, E.; Santoro, V.; Stancari, G.; Anulli, F.; Baldini-Ferroli, R.; Biagini, M.E.; Boscolo, M.; Calcaterra, A.; Drago, A.; Finocchiaro, G.; Guiducci, S.; Isidori, G.; Pacetti, S.; Patteri, P.; Peruzzi, I.M.; Piccolo, M.; Preger, M.A.; Raimondi, P.; Rama, M.; Vaccarezza, C.; Zallo, A.; Zobov, M.; De Sangro, R.; Buzzo, A.; Lo Vetere, M.; Macri, M.; Monge, M.R.; Passaggio, S.; Patrignani, C.; Robutti, E.; Tosi, S.; Matias, J.; Panduro Vazquez, W.; Borzumati, F.; Eyges, V.; Prell, S.A.; Pedlar, T.K.; Korpar, S.; Pestonik, R.; Staric, M.; Neubert, M.; Denig, A.G.; Nierste, U.; Agoh, T.; Ohmi, K.; Ohnishi, Y.; Fry, J.R.; Touramanis, C.; Wolski, A.; Golob, B.; Krizan, P.; Flaecher, H.; Bevan, A.J.; Di Lodovico, F.; George, K.A.; Barlow, R.; Lafferty, G.; Jawahery, A.; Roberts, D.A.; Simi, G.; Patel, P.M.; Robertson, S.H.; Lazzaro, A.; Palombo, F.; Kaidalov, A.; Buras, A.J.; Tarantino, C.; Buchalla, G.; Sanda, A.I.; D'Ambrosio, G.; Ricciardi, G.; Bigi, I.; Jessop, C.P.; Losecco, J.M.; Honscheid, K.; Arnaud, N.; Chehab, R.; Fedala, Y.; Polci, F.; Roudeau, P.; Sordini, V.; Soskov, V.; Stocchi, A.; Variola, A.; Vivoli, A.; Wormser, G.; Zomer, F.; Bertolin, A.; Brugnera, R.; Gagliardi, N.; Gaz, A.; Margoni, M.; Morandin, M.; Posocco, M.; Rotondo, M.; Simonetto, F.; Stroili, R.; Bonneaud, G.R.; Lombardo, V.; Calderini, G.; Ratti, L.; Speziali, V.; Biasini, M.; Covarelli, R.; Manoni, E.; Servoli, L.; Angelini, C.; Batignani, G.; Bettarini, S.; Bosi, F.; Carpinelli, M.; Cenci, R.; Cervelli, A.; Dell'Orso, M.; Forti, F.; Giannetti, P.; Giorgi, M.; Lusiani, A.; Marchiori, G.; Massa, M.; Mazur, M.A.; Morsani, F.; Neri, N.; Paoloni, E.; Raffaelli, F.; Rizzo, G.; Walsh, J.; Braun, V.; Lenz, A.; Adams, G.S.; Danko, I.Z.; Baracchini, E.; Bellini, F.; Cavoto, G.; D'Orazio, A.; Del Re, D.; Di Marco, E.; Faccini, R.; Ferrarotto, F.; Gaspero, Mario; Jackson, P.; Martinelli, G.; Mazzoni, M.A.; Morganti, Silvio; Piredda, G.; Renga, F.; Silvestrini, L.; Voena, C.; Catani, L.; Di Ciaccio, A.; Messi, R.; Santovetti, E.; Satta, A.; Ciuchini, M.; Lubicz, V.; Wilson, F.F.; Godang, R.; Chen, X.; Liu, H.; Park, W.; Purohit, M.; Trivedi, A.; White, R.M.; Wilson, J.R.; Allen, M.T.; Aston, D.; Bartoldus, R.; Brodsky, S.J.; Cai, Y.; Coleman, J.; Convery, M.R.; DeBarger, S.; Dingfelder, J.C.; Dubois-Felsmann, G.P.; Ecklund, S.; Fisher, A.S.; Haller, G.; Heifets, S.A.; Kaminski, J.; Kelsey, M.H.; Kocian, M.L.; Leith, D.W.G.S.; Li, N.; Luitz, S.; Luth, V.; MacFarlane, D.; Messner, R.; Muller, D.R.; Nosochkov, Y.; Novokhatski, A.; Pivi, M.; Ratcliff, B.N.; Roodman, A.; Schwiening, J.; Seeman, J.; Snyder, A.; Sullivan, M.; Va'Vra, J.; Wienands, U.; Wisniewski, W.; Stoeck, H.; Cheng, H.Y.; Li, H.N.; Keum, Y.Y.; Gronau, M.; Grossman, Y.; Bianchi, F.; Gamba, D.; Gambino, P.; Marchetto, F.; Menichetti, Ezio A.; Mussa, R.; Pelliccioni, M.; Dalla Betta, G.F.; Bomben, M.; Bosisio, L.; Cartaro, C.; Lanceri, L.; Vitale, L.; Azzolini, V.; Bernabeu, J.; Lopez-March, N.; Martinez-Vidal, F.; Milanes, D.A.; Oyanguren, A.; Paradisi, P.; Pich, A.; Sanchis-Lozano, M.A.; Kowalewski, Robert V.; Roney, J.M.; Back, J.J.; Gershon, T.J.; Harrison, P.F.; Latham, T.E.; Mohanty, G.B.; Petrov, A.A.; Pierini, M.; INFN

    2007-01-01

    The physics objectives of SuperB, an asymmetric electron-positron collider with a luminosity above 10^36/cm^2/s are described, together with the conceptual design of a novel low emittance design that achieves this performance with wallplug power comparable to that of the current B Factories, and an upgraded detector capable of doing the physics in the SuperB environment.

  19. Properties of Super-Poisson Processes and Super-Random Walks with Spatially Dependent Branching Rates

    Institute of Scientific and Technical Information of China (English)

    Yan Xia REN

    2008-01-01

    The global supports of super-Poisson processes and super-random walks with a branching mechanism ψ(z)=z2 and constant branching rate are known to be noncompact. It turns out that, for any spatially dependent branching rate, this property remains true. However, the asymptotic extinction property for these two kinds of superprocesses depends on the decay rate of the branching-rate function at infinity.

  20. A generalized super AKNS hierarchy associated with Lie superalgebra sl(2|1) and its super bi-Hamiltonian structure

    Science.gov (United States)

    Han, Jingwei; Yu, Jing

    2017-03-01

    Starting from a 3 × 3 matrix-valued spectral problem associated with a Lie superalgebra sl(2|1), a generalized super Ablowitz-Kaup-Newell-Segur (AKNS) hierarchy is derived. The resulting super AKNS hierarchy has a super bi-Hamiltonian structure by the supertrace identity.

  1. Super SI燃烧方式试验研究%Super SI Combustion Mode

    Institute of Scientific and Technical Information of China (English)

    沈义涛; 吕世亮; 尹琪; 杨嘉林; 高卫民

    2011-01-01

    The super spark ignition (Super SI) combustion mode, which was the ignition combustion of lean mixture at the temperature of close spontaneous combustion, was researched and its combustion characteristic and feasibility were analyzed.The results indicate that the increase of intake temperature can reduce the cyclic variation of Pmi obviously, shorten the combustion duration and extend the lean limit of SI combustion under the condition of lean mixture. Accordingly, Super SI combustion has the advantages of high thermal efficiency and controllable combustion process.%研究了Super Spark Ignition(Super SI)燃烧方式,即稀薄混合气在近自燃温度状态下点燃燃烧,分析了这种燃烧方式的可行性和燃烧特性.研究结果表明,混合气稀薄时提高发动机的进气温度可显著降低平均指示压力(pmi)的循环波动,缩短燃烧持续期,拓展点燃燃烧的稀薄极限;Super SI燃烧方式具有热效率高、燃烧过程可控的优点.

  2. The 2015 super-resolution microscopy roadmap

    Science.gov (United States)

    Hell, Stefan W.; Sahl, Steffen J.; Bates, Mark; Zhuang, Xiaowei; Heintzmann, Rainer; Booth, Martin J.; Bewersdorf, Joerg; Shtengel, Gleb; Hess, Harald; Tinnefeld, Philip; Honigmann, Alf; Jakobs, Stefan; Testa, Ilaria; Cognet, Laurent; Lounis, Brahim; Ewers, Helge; Davis, Simon J.; Eggeling, Christian; Klenerman, David; Willig, Katrin I.; Vicidomini, Giuseppe; Castello, Marco; Diaspro, Alberto; Cordes, Thorben

    2015-11-01

    Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly with respect to the study of living cells and organisms. Unfortunately, the applicability of the optical microscope is limited, since the diffraction of light imposes limitations on the spatial resolution of the image. Consequently the details of, for example, cellular protein distributions, can be visualized only to a certain extent. Fortunately, recent years have witnessed the development of ‘super-resolution’ far-field optical microscopy (nanoscopy) techniques such as stimulated emission depletion (STED), ground state depletion (GSD), reversible saturated optical (fluorescence) transitions (RESOLFT), photoactivation localization microscopy (PALM), stochastic optical reconstruction microscopy (STORM), structured illumination microscopy (SIM) or saturated structured illumination microscopy (SSIM), all in one way or another addressing the problem of the limited spatial resolution of far-field optical microscopy. While SIM achieves a two-fold improvement in spatial resolution compared to conventional optical microscopy, STED, RESOLFT, PALM/STORM, or SSIM have all gone beyond, pushing the limits of optical image resolution to the nanometer scale. Consequently, all super-resolution techniques open new avenues of biomedical research. Because the field is so young, the potential capabilities of different super-resolution microscopy approaches have yet to be fully explored, and uncertainties remain when considering the best choice of methodology. Thus, even for experts, the road to the future is sometimes shrouded in mist. The super-resolution optical microscopy roadmap of Journal of Physics D: Applied Physics addresses this need for clarity. It provides guidance to the outstanding questions through a collection of short review articles from experts in the field, giving a thorough

  3. Gut microbiota and allogeneic transplantation.

    Science.gov (United States)

    Wang, Weilin; Xu, Shaoyan; Ren, Zhigang; Jiang, Jianwen; Zheng, Shusen

    2015-08-23

    The latest high-throughput sequencing technologies show that there are more than 1000 types of microbiota in the human gut. These microbes are not only important to maintain human health, but also closely related to the occurrence and development of various diseases. With the development of transplantation technologies, allogeneic transplantation has become an effective therapy for a variety of end-stage diseases. However, complications after transplantation still restrict its further development. Post-transplantation complications are closely associated with a host's immune system. There is also an interaction between a person's gut microbiota and immune system. Recently, animal and human studies have shown that gut microbial populations and diversity are altered after allogeneic transplantations, such as liver transplantation (LT), small bowel transplantation (SBT), kidney transplantation (KT) and hematopoietic stem cell transplantation (HTCT). Moreover, when complications, such as infection, rejection and graft versus host disease (GVHD) occur, gut microbial populations and diversity present a significant dysbiosis. Several animal and clinical studies have demonstrated that taking probiotics and prebiotics can effectively regulate gut microbiota and reduce the incidence of complications after transplantation. However, the role of intestinal decontamination in allogeneic transplantation is controversial. This paper reviews gut microbial status after transplantation and its relationship with complications. The role of intervention methods, including antibiotics, probiotics and prebiotics, in complications after transplantation are also discussed. Further research in this new field needs to determine the definite relationship between gut microbial dysbiosis and complications after transplantation. Additionally, further research examining gut microbial intervention methods to ameliorate complications after transplantation is warranted. A better understanding of the

  4. COMBINED HEART-KIDNEY TRANSPLANTATION

    OpenAIRE

    V. N. Poptsov

    2016-01-01

    Combined heart-kidney transplantation may be performed in carefully selected patients with end-stage heart disease and renal failure. There are two types of combined transplantation of heart and kidney: 1) simultaneous heart-kidney transplantation (SHKT) from the same donor; 2) staged transplantation of heart and kidneys from two genetically different donors. The ISHLT registry in 2014 reported an increase in the number of SHKT over the years: from 22 in 1994 to 97 in 2012. World experience d...

  5. The Chennai floods of 2015: urgent need for ethical disaster management guidelines.

    Science.gov (United States)

    Mariaselvam, Suresh; Gopichandran, Vijayaprasad

    2016-01-01

    India has suffered several natural disasters in recent years. The super cyclone of Orissa in 1999 and the tsunami on the southeastern coast in 2004, both led to major developments in disaster management abilities in the country. Almost a decade after the last major disaster that hit south India, the recent floods in Chennai in 2015 brought to the fore a whole set of ethical considerations. There were issues of inequity in the relief and response activities, conflicts and lack of coordination between the government and non-government relief and response, more emphasis on short-term relief activities rather than rehabilitation and reconstruction, and lack of crisis standards of care in medical services. This paper highlights these ethical issues and the need for ethical guidelines and an ethical oversight mechanism for disaster management and response.

  6. Idiopathic pulmonary fibrosis with complication of severe respiratory failure, right heart failure, and steroid induced diabetes – qualification for lung transplantation as a matter of urgency

    Directory of Open Access Journals (Sweden)

    Beata P. Kraśnicka-Sokół

    2016-09-01

    Full Text Available A 62-year-old woman 146 cm tall and weighing 50 kg, due to idiopathic pulmonary fibrosis, was firstly approved for lung transplantation according to the planned mode. Due to the low height of the patient there were difficulties in the selection of the donor and prolonged waiting time for the surgery. Rapid progression of pulmonary hypertension and steroid-induced diabetes forced us to change the mode of the procedure to urgent. The description of the case shows the difficulties in therapy and choosing the appropriate time for lung transplantation. In this case, the collaboration of specialists from various fields in the decision on transplant is noteworthy.

  7. [Liver transplantation and pregnancy].

    Science.gov (United States)

    Goarin, A-C; Homer, L

    2010-11-01

    Management during their sexual life of patients with a liver transplantation is a more or less common situation depending centers. Based on literature review, a focus on management of recipient women was conducted, from contraception to pregnancy, describing the complications related to the status of transplant recipient, but also those that may be related to immunosuppressive agents. If fertility and access to contraception are only slightly modified by graft, complications related to graft or immunosuppressive drugs can affect the pregnancy. On the maternal side, hypertension and preeclampsia are more common, as well as renal dysfunction, iatrogenic diabetes and bacterial or viral infections, acute rejection and graft loss do not appear to be influenced by pregnancy. The fetus is also exposed to risks such as induced prematurity and IUGR. Pregnancy in recipients of hepatic grafts therefore requires joint follow-up by transplant specialist and perinatologist, which leads in most cases to successful outcome for mother and child.

  8. Pediatric liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Marco Spada; Silvia Riva; Giuseppe Maggiore; Davide Cintorino; Bruno Gridelli

    2009-01-01

    In previous decades, pediatric liver transplantation has become a state-of-the-art operation with excellent success and limited mortality. Graft and patient survival have continued to improve as a result of improvements in medical, surgical and anesthetic management, organ availability, immunosuppression, and identification and treatment of postoperative complications. The utilization of split-liver grafts and living-related donors has provided more organs for pediatric patients. Newer immunosuppression regimens, including induction therapy, have had a significant impact on graft and patient survival. Future developments of pediatric liver transplantation will deal with long-term followup, with prevention of immunosuppression-related complications and promotion of as normal growth as possible. This review describes the state-of-the-art in pediatric liver transplantation.

  9. Lung transplantation for cystic fibrosis

    NARCIS (Netherlands)

    Adler, Frederick R; Aurora, Paul; Barker, David H; Barr, Mark L; Blackwell, Laura S; Bosma, Otto H; Brown, Samuel; Cox, D R; Jensen, Judy L; Kurland, Geoffrey; Nossent, George D; Quittner, Alexandra L; Robinson, Walter M; Romero, Sandy L; Spencer, Helen; Sweet, Stuart C; van der Bij, Wim; Vermeulen, J; Verschuuren, Erik A M; Vrijlandt, Elianne J L E; Walsh, William; Woo, Marlyn S; Liou, Theodore G

    2009-01-01

    Lung transplantation is a complex, high-risk, potentially life-saving therapy for the end-stage lung disease of cystic fibrosis (CF). The decision to pursue transplantation involves comparing the likelihood of survival with and without transplantation as well as assessing the effect of wait-listing

  10. Predicting Outcome of Heart Transplantation

    NARCIS (Netherlands)

    Tjang, Y.S.

    2008-01-01

    Heart transplantation has become the treatment of choice for patients with end-stage heart diseases. Originally, strict recipient and donor selection criteria were developed to minimize morbidity and mortality after heart transplantation. However, the increasing demand for heart transplantation has

  11. Renal transplantation in developing countries.

    Science.gov (United States)

    Akoh, Jacob A

    2011-07-01

    Patients with established renal failure, living in developing countries, face many obstacles including lack of access to transplantation centers, quality and safety issues, and exploittation associated with transplant tourism. This review aims to determine the state and outcome of renal transplantation performed in developing countries and to recommend some solutions. The lack of suitable legislation and infrastructure has prevented growth of deceased donor programs; so, living donors have continued to be the major source of transplantable kidneys. Transplant tourism and commercial kidney transplants are associated with a high incidence of surgical complications, acute rejection and invasive infection, which cause major morbidity and mortality. Developing transplant services worldwide has many benefits - improving the results of transplantation as they would be performed legally, increasing the donor pool, making transplant tourism unnecessary and granting various governments the moral courage to fight unacceptable practices. A private-public partnership underpinned by transparency, public audit and accountability is a prerequisite for effective transplant services in the developing world. Finally, lack of dialysis facilities coupled with better outcomes in patients spending <6 months on dialysis prior to transplantation favor pre-emptive transplantation in developing countries.

  12. The "weekend effect" in pediatric surgery - increased mortality for children undergoing urgent surgery during the weekend.

    Science.gov (United States)

    Goldstein, Seth D; Papandria, Dominic J; Aboagye, Jonathan; Salazar, Jose H; Van Arendonk, Kyle; Al-Omar, Khaled; Ortega, Gezzer; Sacco Casamassima, Maria Grazia; Abdullah, Fizan

    2014-07-01

    For a number of pediatric and adult conditions, morbidity and mortality are increased when patients present to the hospital on a weekend compared to weekdays. The objective of this study was to compare pediatric surgical outcomes following weekend versus weekday procedures. Using the Nationwide Inpatient Sample and the Kids' Inpatient Database, we identified 439,457 pediatric (Pediatric patients undergoing common urgent surgical procedures during a weekend admission have a higher adjusted risk of death, blood transfusion, and procedural complications. While the exact etiology of these findings is not clear, the timing of surgical procedures should be considered in the context of systems-based deficiencies that may be detrimental to pediatric surgical care. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Is urgent CT angiography necessary in cases of acute lower gastrointestinal bleeding?

    Science.gov (United States)

    Díaz, A Martín; Rodríguez, L Fernández; de Gracia, M Martí

    2017-01-06

    Acute lower gastrointestinal bleeding usually presents as hematochezia, rectal bleeding or melena and represents 1-2% of the medical appointments in the Emergency Services. Mortality reaches the 30-40% and it is highly related with the severity and associated comorbidity. Most clinical practice guidelines include colonoscopy at some point in the diagnostic and therapeutic process (urgent for severe cases and ambulatory for mild ones) and look for predictors of severity. In the last years, there have been numerous studies where is clear the relevance and complementarity of advanced diagnostic imaging techniques, gradually incorporated as an alternative or second step in severe cases. Therefore, we have made a review of current scientific evidence to establish a clinical prediction rule for optimal indication of CT angiography in these patients. However, future studies providing greater robustness and level of evidence are necessary.

  14. [Urgent therapeutic penetrating autokeratoplasty for a purulent corneal ulcer in the only functional eye].

    Science.gov (United States)

    Onishchenko, A L; Kolbasko, A V; Tatarnikova, G N; Mamontova, É G

    2014-01-01

    The article presents a case of severe purulent corneal ulcer in the only functional eye of a young patient with Frank-Kamenetsky glaucoma and high-degree myopia. Combination therapy was ineffective and the patient developed a descemetocele. Due to the absence of cadaver corneas and small size of the only available conserved Alloplant cornea, the contralateral cornea (of the blind eye, which was enucleated under general anesthesia) was used for urgent therapeutic penetrating autokeratoplasty. Postoperative period was complicated with ocular hypertension, which was surgically resolved. To overcome the critical situation around keratoplasty, with results from Russian regulation gaps, the authors suggest creating interregional eye banks in large cities that would provide sampling, conservation and storage control of donor material in accordance with the existing legislation.

  15. [Urgent action needed to raise public awareness of age-related macular degeneration in China].

    Science.gov (United States)

    Chen, You-xin

    2009-05-01

    Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. The impact of AMD to the economics, society and the patients are huge. However, the awareness of AMD is alarmingly low. Even in developed countries, the awareness of AMD is below 30%. In terms of the risk factors of AMD, the awareness is also quite low, e.g., only 32% were aware of the causal link between smoking and AMD. Although cataract is the leading cause of the blindness in China, as the economic and social progress, as the coming of the aging society, as people pursuing higher quality of life, AMD will become a unignoring public health problem. Thus, it is urgent to take action now to increase the public awareness of AMD.

  16. The best management for 'crescendo biliary colic' is urgent laparoscopic cholecystectomy.

    Science.gov (United States)

    Robertson, G S; Wemyss-Holden, S A; Maddern, G J

    1998-11-01

    Gallbladder disease due to stones is well recognised as falling into two categories, presenting with either chronic symptoms or developing acute cholecystitis or other complications. We describe an intermediate group of 14 patients (11 women, three men, median age 31 years) presenting with 4-14 days of at least daily attacks of resolving biliary colic, who underwent early laparoscopic cholecystectomy within 24 hours of presentation. None had any evidence of acute inflammation, either at laparoscopy or on histology. Their surgery was straightforward with operating times ranging from 35-80 minutes and no complications. Patients with 'crescendo biliary colic' are often young women who can rarely afford invalidity. Rather than the current practice of analgesia for each attack and elective surgery weeks later, they are optimally managed by urgent laparoscopic cholecystectomy, preventing the development of complications and minimising the need for further medical involvement.

  17. Nosocomial outbreak of Pantoea agglomerans in a pediatric urgent care center

    Directory of Open Access Journals (Sweden)

    Eliana L. Bicudo

    Full Text Available Pantoea agglomerans is a Gram-negative bacterium whose isolates can be found in blood cultures and other secretions. This article described one outbreak of sepsis due to this bacterium in the pediatric urgent care center of a tertiary hospital, in Brasilia, Federal District. This was a case-control study and it evaluated the risk factors for acquisition of nosocomial sepsis caused by Pantoea agglomerans. Six case-patients and 15 control-patients have been found. The risk factors were: vomiting in the internment and presence of solution compositions in the intravenous hydration therapy received in bigger number than 2 compositions. The transference tube used for the compositions was contaminated with Pantoea agglomerans, characterizing the outbreak with common source. The evolution of all the patients was favorable.

  18. Hypersensitivity to aspirin and urgent percutaneous coronary intervention: A therapeutic challenge.

    Science.gov (United States)

    Duarte, Tatiana; Gonçalves, Sara; Sá, Catarina; Marinheiro, Rita; Rodrigues, Rita; Seixo, Filipe; Tomas, Elza; Caria, Rui

    2016-11-01

    Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs are common and five types of reactions have been defined. The prevalence of such reactions in patients with myocardial infarction is unclear, and so antiplatelet therapy in this population is a challenge. Various desensitization protocols have been developed but there are no specific guidelines for their use. The authors present the case of a patient with acute coronary syndrome and aspirin hypersensitivity referred for urgent coronary angiography. Aspirin desensitization therapy is safe and successful in many patients, but more randomized trials are needed to confirm its benefits in coronary artery disease patients. Copyright © 2016 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. Echinococcosis of Iliopsoas Muscle and Anaphylaxis as the Cause of Urgent Laparotomy

    Directory of Open Access Journals (Sweden)

    A Petrić

    2014-12-01

    Full Text Available Echinococcosis is an infectious disease which in humans is caused by the larval stadium of two types of parasites (Echinococcus granulosus and Echinococcus multilocularis. It is most frequently localized in the liver, lungs and rarely in muscles. The parasite significantly affects the immune system of the host, which is why anaphylactic reactions are not rare, especially in cases of cyst rupture. This paper presents the case of a 53-year old woman who had urgent laparotomy on the presumed basis of rupture of ovarian tumour, with intra-abdominal haemorrhage and shock. It turned out to be echinococcosis of the iliopsoas muscle and anaphylactic reaction. The differential diagnosis of adnexal tumours should take into consideration echinococcosis as well. Symptoms of anaphylactic shock in the case of parasitic cyst rupture can easily be confused with the signs of haemorrhagic shock.

  20. The Solution Construction of Heterotic Super-Liouville Model

    Institute of Scientific and Technical Information of China (English)

    YANG Zhan-Ying; ZHEN Yi

    2001-01-01

    We investigate the heterotic super-Liouville model on the base of the basic Lie super-algebra Osp(1|2).Using the super extension of Leznov-Saveliev analysis and Drinfeld Sokolov linear system, we construct the explicit solution of the heterotic super-Liouville system in component form. We also show that the solutions are local and periodic by calculating the exchange relation of the solution. Finally starting from the action of heterotic super-Liou ville model, we obtain the conserved current and conserved charge which possessed the BR ST properties.

  1. Total hip arthroplasty for femoral neck fractures as an urgent procedure

    Directory of Open Access Journals (Sweden)

    Radoičić Dragan

    2017-01-01

    Full Text Available Background/Aim. Total hip arthroplasty (THA is one of the most widely accepted operative methods for femoral neck fracture (FNF in elderly. However, the data on the early THA for FNF are very limited. The aim of this study to determine if there were differences in postoperative complications and functional outcomes between an urgent and delayed THA following FNF. Methods. This prospective study included a total of 244 patients who had THA following FNF from January 2010 to January 2013. In the first group 41 FNF patients were treated with THA within less than 12 hours of admission. A total of 203 FNF patients were operated in delayed settings, of whom 162 required prolonged preoperative processing and comorbidities correction. The group II consisted of 41 FNF patients who were fit for the early surgery at admission, but the operation was delayed due to institution related reasons. Main outcome measurements included mortality, functional outcome assessement, cardiological and pulmonary complications, pressure ulcers, dislocations, infections, length of hospitalization and revisions. Results. There were no differences in terms of age, gender, type of implants, neither in mortality, nor complications. There were differences in hospital length of stay [t (51.72 = -10.25, p < 0.001]. The patients operated within less than 12 hours of admission, had significantly better scores at all three time points of functional outcome assessment: at discharge t (80 = 2.556, p < 0.012; one month t (80 = 4.731, p < 0.001; three months t (80 = 5.908, p < 0.001. Conclusion. THA for FNF as an urgent procedure is not a widely accepted concept. Our findings indicate that the early operative treatment, does not worsen clinical outcomes, and our results give an advantage to the policy of the early THA for FNF.

  2. Current status of alcohol marketing policy--an urgent challenge for global governance.

    Science.gov (United States)

    Casswell, Sally

    2012-03-01

    To review research literature and available information on the extent and impacts of marketing, current policy response and the interests engaged in the policy debate in order to inform recommendations for policy change on alcohol marketing. Relevant literature, including systematic reviews and publicly available information (websites and participant observation) is reviewed and synthesized. Alcohol marketing has expanded markedly in the past 50 years and, while there remains uncertainty about the impact across the population, there is now clear evidence of its impact on the consumption of young people. Few countries have effective policy in place restricting alcohol marketing, and there is a lack of an international response to alcohol marketing which crosses national boundaries. The protection of alcohol marketing has been a major focus for vested interest groups and this has affected governmental response at national and international levels. There has been a lack of non-governmental organization engagement. The policy response to tobacco marketing provides a clear contrast to that of alcohol marketing policy and provides a model for alcohol marketing policy. The global exposure of young people to alcohol marketing requires an urgent policy response. The Framework Convention on Tobacco Control provides an appropriate model for global governance to control alcohol marketing. There are extant examples of national level legislation achieving comprehensive bans with France's Loi Evin providing a feasible model. Resources from philanthropic organizations to allow non-governmental organization engagement are urgently required, as is engagement by the governmental sector independent of commercial influence. © 2012 The Author, Addiction © 2012 Society for the Study of Addiction.

  3. Adaptive behavior, functional outcomes, and quality of life outcomes of children requiring urgent ICU admission.

    Science.gov (United States)

    Ebrahim, Shanil; Singh, Simran; Hutchison, Jamie S; Kulkarni, Abhaya V; Sananes, Renee; Bowman, Kerry W; Parshuram, Christopher S

    2013-01-01

    To describe the adaptive behavior and functional outcomes, and health-related quality of life of children who were urgently admitted to the ICU. Prospective observational study. Critical Care Medicine program at a University-affiliated pediatric institution. Urgently admitted patients, aged 1 month to 18 yrs. None. We evaluated children's adaptive behavior functioning with the Vineland Adaptive Behavior Scale-2, functional outcomes with the pediatric cerebral performance category and pediatric overall performance category, and health-related quality of life with the Pediatric Quality of Life Inventory 4 and Visual Analogue Scale. We enrolled 91 children and 65 (71%) completed the 1-month assessment. Patients had a mean (SD) Vineland Adaptive Behavior Scale-2 rating of 83.2 (± 24.8), considered to be moderate-low adaptive behavior functioning. From baseline to 1 month, pediatric cerebral performance category ratings did not significantly change (p = 0.59) and pediatric overall performance category ratings significantly improved (p = 0.03). Visual Analogue Scale ratings significantly worsened from baseline to 1 wk (p adaptive behavior functioning. Neurological admissions, worse pediatric cerebral performance category score at baseline, longer ICU stay, and longer duration of extracorporeal membrane oxygenation were independently associated with worse functional outcome. Worse pediatric cerebral performance category score at baseline, longer ICU stay, and longer duration of extracorporeal membrane oxygenation were independently associated with worse health-related quality of life. Children surviving PICU have significant adaptive behavior functioning and functional morbidity and reduced health-related quality of life. Although neurologic morbidity following ICU was associated with baseline state, we found that resuscitation intensity and illness severity factors were independently associated with the development of acquired brain injury and reduced quality of life.

  4. Problems and Urgent Tasks of Development of the Theory of the Production Strategy of an Enterprise

    Directory of Open Access Journals (Sweden)

    Omelianenko Tetiana V.

    2013-11-01

    Full Text Available The article is devoted to identification of problem aspects and setting urgent tasks of development of the theory of production strategy of an enterprise. It shows that formation of the foundations of the theory of productiuon strategy started in the end of 60s and beginning of 70s of the twentieth century due to efforts of a number of researchers from western industrially developed countries. It establishes that today the theory of production strategy of an enterprise has a number of paradigmal provisions, generalisation of which shows that the production strategy is a component of the general strategy of an organisation, its goal is to provide the enterprise with strategically important competitive advantages, it refers to the category of functional strategies and is specified in the set of production and strategic decisions that cover the technological, resource, organisational and other aspects of the production activity of the enterprise, the subordinate character is inherent in it since it is developed for support of the general corporate and business strategy of the enterprise. Understanding the idea of the modern production and strategic paradigm made it possible to identify problem planes and set urgent tasks of further development of the theory of production strategy of an enterprise. These tasks are: development of methodological grounds of the study of production strategies of enterprises, systematisation of factors and specification of principles of formation of the production strategy, typologisation of traditional production strategies and specification of characteristic features of the newest, just forming and establishing in realities of the post-industrial environment, strategies.

  5. Chemokine Receptors and Transplantation

    Institute of Scientific and Technical Information of China (English)

    Jinquan Tan; Gang Zhou

    2005-01-01

    A complex process including both the innate and acquired immune responses results in allograft rejection. Some chemokine receptors and their ligands play essential roles not only for leukocyte migration into the graft but also in facilitating dendritic and T cell trafficking between lymph nodes and the transplant in the early and late stage of the allogeneic response. This review focuses on the impact of these chemoattractant proteins on transplant outcome and novel diagnostic and therapeutic approaches for antirejection therapy based on targeting of chemokine receptors and/or their ligands. Cellular & Molecular Immunology.

  6. [Psychosocial indication of liver transplantation for alcohol-related liver failure: current controversies and imminent issues in Japanese society].

    Science.gov (United States)

    Kiuchi, Tetsuya

    2012-10-01

    Organ transplant therapy is becoming a usual practice also in Japan, which dramatically improves the length and quality of life in patients with end-stage organ disease. Liver transplantation was resumed in Japan much later than that in the West and is continued now under unique circumstances where more than 90% of grafts come from living donors. Nevertheless the number of liver transplantation for alcohol-related liver failure shows a sharp rise to the level comparable to the West, and not a few physical and/or psychosocial problems caused by recidivism after transplantation are coming up. To find appropriate solutions to how to predict recidivism and define psychosocial indication of liver transplantation in our society, and to how to monitor and support sobriety after transplantation, there is an urgent need for multidisciplinary management by hepatologist, transplant surgeon, psychiatrist, and dependence specialist. Life-saving therapy and dependence management are expected to work closely together from the viewpoints of transparency, equity, utility, and autonomy requested in transplant therapy, protection of living donors, and consideration for donor family and public emotion.

  7. Transplantation of autologous bone marrow stromal cells (BMSC for CNS disorders – Strategy and tactics for clinical application

    Directory of Open Access Journals (Sweden)

    Satoshi Kuroda

    2010-01-01

    Full Text Available Background – There is increasing evidence that the transplanted bone marrow stromal cells (BMSC significantly promote functional recovery after central nervous system (CNS damage in the animal models of various kinds of CNS disorders, including cerebral infarct, brain contusion and spinal cord injury. However, there are several shortages of information when considering clinical application of BMSC transplantation for patients with neurological disorders. In this paper, therefore, we discuss what we should clarify to establish cell transplantation therapy in clinical situation and describe our recent works for this purpose.Methods and Results – The BMSC have the ability to alter their gene expression profile and phenotype in response to the surrounding circumstances and to protect the neurons by producing some neurotrophic factors. They also promote neurite extension and rebuild the neural circuits in the injured CNS. Using optical imaging and MRI techniques, the transplanted BMSC can non-invasively be tracked in the living animals for at least 8 weeks after transplantation. Functional imaging such as PET scan may have the potential to assess the beneficial effects of BMSC transplantation. The BMSC can be expanded using the animal protein-free culture medium, which would maintain their potential of proliferation, migration, and neural differentiation.Conclusion – It is urgent issues to develop clinical imaging technique to track the transplanted cells in the CNS and evaluate the therapeutic significance of BMSC transplantation in order to establish it as a definite therapeutic strategy in clinical situation in the future

  8. Immediate re-transplantation following early kidney transplant thrombosis.

    LENUS (Irish Health Repository)

    Phelan, Paul J

    2012-02-01

    Allograft thrombosis is a devastating early complication of renal transplantation that ultimately leads to allograft loss. We report here on our experience of nine cases of immediate re-transplantation following early kidney transplant thrombosis at a single centre between January 1990 and June 2009. The mean age was 42.9 years at time of transplant. For seven patients, the allograft thrombosis was their first kidney transplant and seven of the nine cases had a deceased donor transplant. The initial transplants functioned for a mean of 1.67 days and the patients received a second allograft at a mean of 3.1 days after graft failure. All of the re-transplants worked immediately. Four allografts failed after a mean of 52.5 months (2-155 months). Two of these died with a functioning allograft, one failed owing to chronic allograft nephropathy and one owing to persistent acute cellular rejection. The remaining five patients still have a functioning allograft after a mean of 101.8 months (7-187 months). One year allograft and patient survival after re-transplantation were 87.5% and 100% respectively (after 5 years, both were 57%). Immediate re-transplantation following early kidney transplant thrombosis can be a success. It may be considered in selected cases after allograft thrombosis.

  9. Immediate re-transplantation following early kidney transplant thrombosis.

    LENUS (Irish Health Repository)

    Phelan, Paul J

    2011-08-01

    Allograft thrombosis is a devastating early complication of renal transplantation that ultimately leads to allograft loss. We report here on our experience of nine cases of immediate re-transplantation following early kidney transplant thrombosis at a single centre between January 1990 and June 2009. The mean age was 42.9 years at time of transplant. For seven patients, the allograft thrombosis was their first kidney transplant and seven of the nine cases had a deceased donor transplant. The initial transplants functioned for a mean of 1.67 days and the patients received a second allograft at a mean of 3.1 days after graft failure. All of the re-transplants worked immediately. Four allografts failed after a mean of 52.5 months (2-155 months). Two of these died with a functioning allograft, one failed owing to chronic allograft nephropathy and one owing to persistent acute cellular rejection. The remaining five patients still have a functioning allograft after a mean of 101.8 months (7-187 months). One year allograft and patient survival after re-transplantation were 87.5% and 100% respectively (after 5 years, both were 57%). Immediate re-transplantation following early kidney transplant thrombosis can be a success. It may be considered in selected cases after allograft thrombosis.

  10. Rapid detection of Bacillus anthracis spores using a super-paramagnetic lateral-flow immunological detection system.

    Science.gov (United States)

    Wang, Dian-Bing; Tian, Bo; Zhang, Zhi-Ping; Deng, Jiao-Yu; Cui, Zong-Qiang; Yang, Rui-Fu; Wang, Xu-Ying; Wei, Hong-Ping; Zhang, Xian-En

    2013-04-15

    There is an urgent need for convenient, sensitive, and specific methods to detect the spores of Bacillus anthracis, the causative agent of anthrax, because of the bioterrorism threat posed by this bacterium. In this study, we firstly develop a super-paramagnetic lateral-flow immunological detection system for B. anthracis spores. This system involves the use of a portable magnetic assay reader, super-paramagnetic iron oxide particles, lateral-flow strips and two different monoclonal antibodies directed against B. anthracis spores. This detection system specifically recognises as few as 400 pure B. anthracis spores in 30 min. This system has a linear range of 4×10³-10⁶ CFU ml⁻¹ and reproducible detection limits of 200 spores mg⁻¹ milk powder and 130 spores mg⁻¹ soil for simulated samples. In addition, this approach shows no obvious cross-reaction with other related Bacillus spores, even at high concentrations, and has no significant dependence on the duration of the storage of the immunological strips. Therefore, this super-paramagnetic lateral-flow immunological detection system is a promising tool for the rapid and sensitive detection of Bacillus anthracis spores under field conditions.

  11. Sporotrichosis in Renal Transplant Patients

    Directory of Open Access Journals (Sweden)

    Paulo Gewehr

    2013-01-01

    Full Text Available The current report describes two renal transplant recipients who presented with sporotrichosis. In addition, the authors review the general aspects of sporotrichosis in renal transplant recipients reported in the literature. Sporotrichosis is a rare fungal infection in transplant patients and has been reported primarily in renal transplant recipients not treated with antifungal prophylaxis. Extracutaneous forms of sporotrichosis without skin manifestations and no previous history of traumatic injuries have been described in such patients and are difficult to diagnose. Renal transplant recipients with sporotrichosis described in the present report were successfully treated with antifungal therapy including amphotericin B deoxycholate, lipid amphotericin B formulations, fluconazole and itraconazole.

  12. [Running through the liver transplantation].

    Science.gov (United States)

    Grecu, F

    2003-01-01

    An overview of the organization, timing and developing of the liver transplantation is difficult to be made in terms of multiple sequences and a great variety of activities during the developing of such activity. A well-trained transplant team must carry out the potential donor, the liver grafts manipulation and the graft receptor, in the condition of a competitive medical system. A summary presentation, showing the essentials of the proceedings in liver transplantation could be assimilated as a guide of multidisciplinary sequences that leads to the completion of the liver grafting. The common feature of all that means the liver transplantation and generally in organ transplantation is the performance and exactingness.

  13. [Kidney transplant patients without social protection in health: what do patients say about the economic hardships and impact?].

    Science.gov (United States)

    Mercado-Martínez, Francisco Javier; Hernández-Ibarra, Eduardo; Ascencio-Mera, Carlos D; Díaz-Medina, Blanca A; Padilla-Altamira, Cesar; Kierans, Ciara

    2014-10-01

    Kidney transplant is the optimal treatment for renal disease according to biomedical criteria, but the technology is highly expensive. The aim of this article was to examine the economic hardships experienced by kidney transplant patients and the impact on their lives, specifically when they lack social protection in health. The article reports on a qualitative study conducted in Mexico. Twenty-one kidney transplant patients participated. Semi-structured interviews were performed and submitted to content analysis. Patients experience extreme economic hardship due to the high cost of renal therapies, particularly medicines. Such economic problems adversely affect their condition, since many patients report difficulties in maintaining their immunosuppressant medication, attending medical appointments, and curtailing household expenditures, further aggravated by loss of earnings. In conclusion, kidney transplantation is associated with patients' impoverishment when they lack social protection in health. A protection system is urgently needed for this group.

  14. Perioperative period in cardiac transplantation from donors with brain death due to methanol poisoning

    Directory of Open Access Journals (Sweden)

    V. N. Poptsov

    2017-01-01

    Full Text Available The successful use of donor hearts from people died of methanol poisoning helps reducing the deficit of donor organs for patients requiring urgent cardiac transplantation [3]. We present our experience of successful cardiac transplantations from 2 donors who died due to methanol poisoning. Given the possibility of performing a cardiac transplant from this group of donors a protocol has been developed at the V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation which includes clinical, laboratory and instrumental criteria for the selection of heart donor and recipient. The possibility of delayed onset myocardial contractile dysfunction due to methanol poisoning means that a longer conditioningperiod is vital as well as compulsory clinical, laboratory and expert chocardiographic examinations of the potential donor heart.

  15. ABO-Incompatible Kidney Transplantation

    Science.gov (United States)

    Morath, Christian; Zeier, Martin; Döhler, Bernd; Opelz, Gerhard; Süsal, Caner

    2017-01-01

    ABO-incompatible (ABOi) kidney transplantation has long been considered a contraindication to successful kidney transplantation. During the last 25 years, increasing organ shortage enforced the development of strategies to overcome the ABO antibody barrier. In the meantime, ABOi kidney transplantation has become a routine procedure with death-censored graft survival rates comparable to the rates in compatible transplantations. Desensitization is usually achieved by apheresis and B cell-depleting therapies that are accompanied by powerful immunosuppression. Anti-A/B antibodies are aimed to be below a certain threshold at the time of ABOi kidney transplantation and during the first 2 weeks after surgery. Thereafter, even a rebound of anti-A/B antibodies does not appear to harm the kidney transplant, a phenomenon that is called accommodation, but is poorly understood. There is still concern, however, that infectious complications such as viral disease, Pneumocystis jirovecii pneumonia, and severe urinary tract infections are increased after ABOi transplantations. Recent data from the Collaborative Transplant Study show that during the first year after kidney transplantation, one additional patient death from an infectious complication occurs in 100 ABOi kidney transplant recipients. Herein, we review the recent evidence on ABOi kidney transplantation with a focus on desensitization strategies and respective outcomes. PMID:28321223

  16. Living Donor Liver Transplantation

    Science.gov (United States)

    ... be a husband or wife. What are Some Benefits of a Living-donor Liver Transplant? In the ... Not have a selfish motive for donating. Paid donation is illegal in the ... leave for being organ donors. Other employers have similar programs, so check ...

  17. Organ Harvesting and Transplants

    Science.gov (United States)

    Baskette, Kimberly G.; Ritz, John M.

    2010-01-01

    Humans and animals need healthy organs to live. Due to medical conditions and accidents, some organs fail to function properly. For these reasons, the medical community has experimented and can now perform successful organ transplants, allowing patients to continue to live their lives. Many countries have medical programs where individuals can…

  18. Ovary and uterus transplantation.

    Science.gov (United States)

    Gosden, Roger G

    2008-12-01

    Ovarian and uterine transplantation are procedures gaining more attention again because of potential applications in respectively fertility preservation for cancer and other patients and, more tentatively, women with uterine agenesis or hysterectomy. Cryopreservation of tissue slices, and possibly whole organs, is providing opportunities for banking ovaries for indefinite periods before transplanting them back to restore fertility. The natural plasticity of this organ facilitates grafting to different sites where they can be revascularized and rapidly restore the normal physiology of secretion and ovulation. Ischemic damage is a chief limitation because many follicles are lost, at least in avascular grafts, and functional longevity is reduced. Nevertheless, grafts of young ovarian tissue, even after cryopreservation, can be highly fertile in laboratory rodents and, in humans, autografts have functioned for up to 3 years before needing replacement. Transplantation by vascular anastomosis provides potentially longer function but it is technically much more demanding and riskier for the recipient. It is the only practicable method with the uterus, and has enabled successful pregnancies in several species, but not yet in humans. Contrary to claims made many years ago, neither organ is privileged immunologically, and allografts become rapidly rejected except in hosts whose immune system is deficient or suppressed pharmacologically. All in all, transplantation of these organs, especially the ovary, provides a broad platform of opportunities for research and new applications in reproductive medicine and conservation biology.

  19. Lung transplant - slideshow

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/presentations/100120.htm Lung transplant - series—Normal anatomy To use the sharing features on this page, please enable JavaScript. Go to slide 1 out of 5 Go to slide 2 out of ... to slide 5 out of 5 Overview The lungs, which reside in the thorax, or chest cavity, ...

  20. Fatigue after Liver Transplantation

    NARCIS (Netherlands)

    B.T.J. van Ginneken (Berbke)

    2009-01-01

    textabstractLiver transplantation (LTx) has developed from an experimental procedure in the 1960’s to the preferred treatment for end-stage liver disease nowadays. The first human LTx was performed by Starlz and his team in 1963 in Colorado.[1] Unfortunately, this patient died within a few days. The

  1. Guidelines for heart transplantation

    OpenAIRE

    de Jonge, N; Kirkels, J.H.; Klöpping, C.; Lahpor, J.R.; Caliskan, K.; Maat, A.P.W.M.; Brügemann, J; Erasmus, M.E.; Klautz, R. J. M.; Verwey, H.F; Oomen, A.; Peels, C.H.; Golüke, A.E.J.; Nicastia, D.; Koole, M.A.C.

    2008-01-01

    Based on the changes in the field of heart transplantation and the treatment and prognosis of patients with heart failure, these updated guidelines were composed by a committee under the supervision of both the Netherlands Society of Cardiology and the Netherlands Association for Cardiothoracic surgery (NVVC and NVT).

  2. Guidelines for heart transplantation

    NARCIS (Netherlands)

    Kirkels, J. H.; Klopping, C.; Lahpor, J. R.; Caliskan, K.; Maat, A. P. W. M.; Brugemann, J.; Erasmus, M. E.; Klautz, R. J. M.; Verwey, H. F.; Oomen, A.; Peels, C. H.; Goluke, A. E. J.; Nicastia, D. M.; Koole, M. A. C.; Balk, A. H. M. M.; de Jonge, N.

    Based on the changes in the field of heart transplantation and the treatment and prognosis of patients with heart failure, these updated guidelines were composed by a committee under the supervision of both the Netherlands Society of Cardiology and the Netherlands Association for Cardiothoracic

  3. Imaging in liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Settimo Caruso; Roberto Miraglia; Luigi Maruzzelli; Salvatore Gruttadauria; Angelo Luca; Bruno Gridelli

    2009-01-01

    The aim of this study was to illustrate the role of noninvasive imaging tools such as ultrasonography, multidetector row computed tomography, and magnetic resonance imaging in the evaluation of pediatric and adult liver recipients and potential liver donors, and in the detection of potential complications arising from liver transplantation.

  4. Rupture of Renal Transplant

    Directory of Open Access Journals (Sweden)

    Shona Baker

    2015-01-01

    Full Text Available Background. Rupture of renal allograft is a rare and serious complication of transplantation that is usually attributed to acute rejection, acute tubular necrosis, or renal vein thrombosis. Case Presentation. LD, a 26-year-old male with established renal failure, underwent deceased donor transplantation using kidney from a 50-year-old donor with acute kidney injury (Cr 430 mmol/L. LD had a stormy posttransplant recovery and required exploration immediately for significant bleeding. On day three after transplant, he developed pain/graft swelling and another significant haemorrhage with cardiovascular compromise which did not respond to aggressive resuscitation. At reexploration, the renal allograft was found to have a longitudinal rupture and was removed. Histology showed features of type IIa Banff 97 acute vascular rejection, moderate arteriosclerosis, and acute tubular necrosis. Conclusion. Possible ways of avoiding allograft rupture include use of well-matched, good quality kidneys; reducing or managing risk factors that would predispose to delayed graft function; ensuring a technically satisfactory transplant procedure with short cold and warm ischemia times; and avoiding large donor-recipient age gradients.

  5. Hepatitis C and Kidney Transplantation

    Science.gov (United States)

    Carbone, Marco; Cockwell, Paul; Neuberger, James

    2011-01-01

    Hepatitis C virus (HCV) infection is relatively common among patients with end-stage kidney disease (ESKD) on dialysis and kidney transplant recipients. HCV infection in hemodialysis patients is associated with an increased mortality due to liver cirrhosis and hepatocellular carcinoma. The severity of hepatitis C-related liver disease in kidney transplant candidates may predict patient and graft survival after transplant. Liver biopsy remains the gold standard in the assessment of liver fibrosis in this setting. Kidney transplantation, not haemodialysis, seems to be the best treatment for HCV+ve patients with ESKD. Transplantation of kidneys from HCV+ve donors restricted to HCV+ve recipients is safe and associated with a reduction in the waiting time. Simultaneous kidney/liver transplantation (SKL) should be considered for kidney transplant candidates with HCV-related decompensated cirrhosis. Treatment of HCV is more complex in hemodialysis patients, whereas treatment of HCV recurrence in SLK recipients appears effective and safe. PMID:21755059

  6. Hepatitis C and Kidney Transplantation

    Directory of Open Access Journals (Sweden)

    Marco Carbone

    2011-01-01

    Full Text Available Hepatitis C virus (HCV infection is relatively common among patients with end-stage kidney disease (ESKD on dialysis and kidney transplant recipients. HCV infection in hemodialysis patients is associated with an increased mortality due to liver cirrhosis and hepatocellular carcinoma. The severity of hepatitis C-related liver disease in kidney transplant candidates may predict patient and graft survival after transplant. Liver biopsy remains the gold standard in the assessment of liver fibrosis in this setting. Kidney transplantation, not haemodialysis, seems to be the best treatment for HCV+ve patients with ESKD. Transplantation of kidneys from HCV+ve donors restricted to HCV+ve recipients is safe and associated with a reduction in the waiting time. Simultaneous kidney/liver transplantation (SKL should be considered for kidney transplant candidates with HCV-related decompensated cirrhosis. Treatment of HCV is more complex in hemodialysis patients, whereas treatment of HCV recurrence in SLK recipients appears effective and safe.

  7. SuperTools Test and Evaluation Plan

    Energy Technology Data Exchange (ETDEWEB)

    Mannos, Tom J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Mixed Signal ASIC Design

    2017-01-01

    Superconducting electronics (SCE) represents a potential path to efficient exascale computing for HPC and data center applications, but SCE-based circuit design lags far behind its CMOS equivalent. IARPA’s ongoing C3 program and its developing SuperTools program aim to jumpstart SCE R&D with the near-term goal of producing a high-speed, low-energy, 64-bit RISC processor using Josephson Junction based logic cells. SuperTools performers will develop software tools for efficient SCE design and accurate simulation and characterization of JJ-based circuits, which include the RSFQ, RQL, and AQFP logic families. T&E teams from NIST, MIT Lincoln Lab, Berkeley Lab, and Sandia National Labs will evaluate the tools and fabricate test circuits to compare with simulated results. The five-year, three-phase program includes 48 performer deliverables, three annual technical exchange meetings, and annual site visits.

  8. Italian super-eruption larger than thought

    Science.gov (United States)

    Schultz, Colin

    2012-07-01

    Recent research suggested that the super-eruption of the Campi Flegrei caldera volcano in southern Italy about 40,000 years ago may have played a part in wiping out, or forcing the migration of, the Neanderthal and modern human populations in the eastern Mediterranean regions that were covered in ash. Now a new modeling study by Costa et al. suggests that this eruption may have been even larger than previously thought. This Campi Flegrei eruption produced a widespread ash layer known as Campanian Ignimbrite (CI). Using ash thickness measurements collected at 115 sites and a three-dimensional ash dispersal model, the researchers found that the CI super-eruption would have spread 250-300 cubic kilometers of ash across a 3.7-million-square kilometer region—2 to 3 times previous ash volume estimates.

  9. Optical super-resolution microscopy in neurobiology.

    Science.gov (United States)

    Sigrist, Stephan J; Sabatini, Bernardo L

    2012-02-01

    Understanding the highly plastic nature of neurons requires the dynamic visualization of their molecular and cellular organization in a native context. However, due to the limited resolution of standard light microscopy, many of the structural specializations of neurons cannot be resolved. A recent revolution in light microscopy has given rise to several super-resolution light microscopy methods yielding 2-10-fold higher resolution than conventional microscopy. We here describe the principles behind these techniques as well as their application to the analysis of the molecular architecture of the synapse. Furthermore, we discuss the potential for continued development of super-resolution microscopy as necessary for live imaging of neuronal structure and function in the brain.

  10. Super-resolution microscopy: a comparative treatment.

    Science.gov (United States)

    Kasuboski, James M; Sigal, Yury J; Joens, Matthew S; Lillemeier, Bjorn F; Fitzpatrick, James A J

    2012-10-01

    One of the fundamental limitations of optical microscopy is that of diffraction, or in essence, how small a beam of light can be focused by using an optical lens system. This constraint, or barrier if you will, was theoretically described by Ernst Abbe in 1873 and is roughly equal to half the wavelength of light used to probe the system. Many structures, particularly those within cells, are much smaller than this limit and thus are difficult to visualize. Over the last two decades, a new field of super-resolution imaging has been created and been developed into a broad range of techniques that allow routine imaging beyond the far-field diffraction limit of light. In this unit we outline the basic principles of the various super-resolution imaging modalities, paying particular attention to the technical considerations for biological imaging. Furthermore, we discuss their various applications in the imaging of both fixed and live biological samples.

  11. (Super-)renormalizably dressed black holes

    CERN Document Server

    Ayón-Beato, Eloy; Méndez-Zavaleta, Julio A

    2015-01-01

    Black holes supported by self-interacting conformal scalar fields can be considered as renormalizably dressed since the conformal potential is nothing but the top power-counting renormalizable self-interaction in the relevant dimension. On the other hand, potentials defined by powers which are lower than the conformal one are also phenomenologically relevant since they are in fact super-renormalizable. In this work we provide a new map that allows to build black holes dressed with all the (super-)renormalizable contributions starting from known conformal seeds. We explicitly construct several new examples of these solutions in dimensions $D=3$ and $D=4$, including not only stationary configurations but also time-dependent ones.

  12. Super/subradiant second harmonic generation

    Science.gov (United States)

    Koganov, Gennady A.; Shuker, Reuben

    2017-04-01

    A scheme for active second harmonics generation is suggested. The system comprises N three-level atoms in ladder configuration, situated into a resonant cavity. The system generates the field whose frequency is twice the frequency of the pumping laser, and the field phase is locked to the phase of the pumping field. It is found that the system can lase in either superradiant or subradiant regime, depending on the number of atoms N. When N passes some critical value the transition from the super to subradiance occurs in a phase-transition-like manner. Stability study of the steady state supports this conclusion. For experimental realization of the super/subradiant second harmonics generation we propose semiconductor quantum well structures, superconducting quantum circuits, and evanescently coupled waveguides in which equally spaced levels relevant to this study exist.

  13. Pulsating stars in SuperWASP

    Directory of Open Access Journals (Sweden)

    Holdsworth Daniel L.

    2017-01-01

    Full Text Available SuperWASP is one of the largest ground-based surveys for transiting exoplanets. To date, it has observed over 31 million stars. Such an extensive database of time resolved photometry holds the potential for extensive searches of stellar variability, and provide solid candidates for the upcoming TESS mission. Previous work by e.g. [15], [5], [12] has shown that the WASP archive provides a wealth of pulsationally variable stars. In this talk I will provide an overview of the SuperWASP project, present some of the published results from the survey, and some of the on-going work to identify key targets for the TESS mission.

  14. Robust super-resolution without regularization

    Energy Technology Data Exchange (ETDEWEB)

    Pham, T Q [Canon Information Systems Research Australia, 1 Thomas Holt drive, North Ryde, NSW 2113 (Australia); Vliet, L J v [Quantitative Imaging Group, Department of Imaging Science and Technology, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft (Netherlands); Schutte, K [Electro-Optics Group, TNO Defence, Security and Safety, PO Box 96864, 2509 JG The Hague (Netherlands)

    2008-07-15

    Super-resolution restoration is the problem of restoring a high-resolution scene from multiple degraded low-resolution images under motion. Due to imaging blur and noise, this problem is ill-posed. Additional constraints such as smoothness of the solution (i.e. regularization) is often required to obtain a stable solution. While regularizing the cost function is a standard practice in image restoration, we propose a restoration algorithm that does not require this extra regularization term. The robustness of the algorithm is achieved by a robust error norm that does not response to intensity outliers. With the outliers suppressed, our solution behaves similarly to a maximum-likelihood solution under the presence of Gaussian noise. The effectiveness of our algorithm is demonstrated with super-resolution restoration of real infrared image sequences under severe aliasing and intensity outliers.

  15. Penrose Pixels for Super-Resolution.

    Science.gov (United States)

    Ben-Ezra, M; Lin, Zhouchen; Wilburn, Bennett; Zhang, Wei

    2011-07-01

    We present a novel approach to reconstruction-based super-resolution that uses aperiodic pixel tilings, such as a Penrose tiling or a biological retina, for improved performance. To this aim, we develop a new variant of the well-known error back projection super-resolution algorithm that makes use of the exact detector model in its back projection operator for better accuracy. Pixels in our model can vary in shape and size, and there may be gaps between adjacent pixels. The algorithm applies equally well to periodic or aperiodic pixel tilings. We present analysis and extensive tests using synthetic and real images to show that our approach using aperiodic layouts substantially outperforms existing reconstruction-based algorithms for regular pixel arrays. We close with a discussion of the feasibility of manufacturing CMOS or CCD chips with pixels arranged in Penrose tilings.

  16. Temporal super resolution using variational methods

    DEFF Research Database (Denmark)

    Keller, Sune Høgild; Lauze, Francois Bernard; Nielsen, Mads

    2010-01-01

    and intensities are calculated simultaneously in a multiresolution setting. A frame doubling version of our algorithm is implemented and in testing it, we focus on making the motion of high contrast edges to seem smooth and thus reestablish the illusion of motion pictures.......Temporal super resolution (TSR) is the ability to convert video from one frame rate to another and is as such a key functionality in modern video processing systems. A higher frame rate than what is recorded is desired for high frame rate displays, for super slow-motion, and for video/film format...... conversion (where also lower frame rates than recorded is sometimes required). We discuss and detail the requirements imposed by the human visual system (HVS) on TSR algorithms, of which the need for (apparent) fluid motion, also known as the phi-effect, is the principal one. This problem is typically...

  17. Key issues in transplant tourism.

    Science.gov (United States)

    Akoh, Jacob A

    2012-02-24

    Access to organ transplantation depends on national circumstances, and is partly determined by the cost of health care, availability of transplant services, the level of technical capacity and the availability of organs. Commercial transplantation is estimated to account for 5%-10% (3500-7000) of kidney transplants performed annually throughout the world. This review is to determine the state and outcome of renal transplantation associated with transplant tourism (TT) and the key challenges with such transplantation. The stakeholders of commercial transplantation include: patients on the waiting lists in developed countries or not on any list in developing countries; dialysis funding bodies; middlemen, hosting transplant centres; organ-exporting countries; and organ vendors. TT and commercial kidney transplants are associated with a high incidence of surgical complications, acute rejection and invasive infection which cause major morbidity and mortality. There are ethical and medical concerns regarding the management of recipients of organs from vendors. The growing demand for transplantation, the perceived failure of altruistic donation in providing enough organs has led to calls for a legalised market in organ procurement or regulated trial in incentives for donation. Developing transplant services worldwide has many benefits - improving results of transplantation as they would be performed legally, increasing the donor pool and making TT unnecessary. Meanwhile there is a need to re-examine intrinsic attitudes to TT bearing in mind the cultural and economic realities of globalisation. Perhaps the World Health Organization in conjunction with The Transplantation Society would set up a working party of stakeholders to study this matter in greater detail and make recommendations.

  18. Super-pharm的生意经

    Institute of Scientific and Technical Information of China (English)

    韦少雯

    2006-01-01

    Super-pharm,这家可直译为“超级药店”的以色列最大的药品、化妆品及个人护理品零售企业,是由全球排名前几十位的亿万富翁、犹太人Murray Koffler创立的家族企业。

  19. Super Resolution Imaging Applied to Scientific Images

    Science.gov (United States)

    2007-05-01

    investigator, (3) development of Papoulis -Gerchberg method to implement the analytic continuation of spectral details, (4) exploration of contourlet and...off with noise present in the observation. In [30] we make use of Papoulis -Gerchberg algorithm of signal extrapolation to perform Image super...we have used a training database consisting of high resolution images. For Papoulis -Gerchberg method number of iterations and the filter used both

  20. The SuperNova Early Warning System

    OpenAIRE

    Scholberg, K.

    2008-01-01

    A core collapse in the Milky Way will produce an enormous burst of neutrinos in detectors world-wide. Such a burst has the potential to provide an early warning of a supernova's appearance. I will describe the nature of the signal, the sensitivity of current detectors, and SNEWS, the SuperNova Early Warning System, a network designed to alert astronomers as soon as possible after the detected neutrino signal.

  1. (Super-)renormalizably dressed black holes

    OpenAIRE

    Ayón-Beato, Eloy; Hassaïne, Mokhtar; Méndez-Zavaleta, Julio A.

    2015-01-01

    Black holes supported by self-interacting conformal scalar fields can be considered as renormalizably dressed since the conformal potential is nothing but the top power-counting renormalizable self-interaction in the relevant dimension. On the other hand, potentials defined by powers which are lower than the conformal one are also phenomenologically relevant since they are in fact super-renormalizable. In this work we provide a new map that allows to build black holes dressed with all the (su...

  2. Dating With Super Junior-M

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    担心情人节没人陪?还在幻想能与谁约会?2009年2月14日,梦想照进现实,SJ-M将在上海举办“情人Superman-Super Junior-M 2009上海歌会”,化身你的甜蜜情人,与你一起共度浪漫情人节。

  3. Super-Kamiokande - Present and Future

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Y. [Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo, Higashi-Mozumi, Kamioka-chou, Hida-city, Gifu 506-1205 (Japan)

    2004-12-15

    We summarize the latest results on the atmospheric and solar neutrinos from Super-Kamiokande. The atmospheric neutrino oscillation analyses with two flavors and with three flavor are discussed and the new results based on the L/E analysis are shown. New solar neutrino results based on the un-binned method is discussed. The current status of SK-II and the future prospects for SK neutrino oscillation experiment are summarized.

  4. The (Super)String Theories' Problems

    CERN Document Server

    Naboulsi, R

    2003-01-01

    (Super)String theories are theoretical ideas that go beyond the standard model of particle and high energy physics and show promise for unifying all forces in nature including the gravitational one. In this unification a prominent role is played by the duality symmetries which relate different theories. I present a review of these developements and discuss their problems and possible impact in low-energy physics. We explain and discuss some ideas concerning string field theories from noncommutative geometry.

  5. T-Duality from super Lie n-algebra cocycles for super p-branes

    CERN Document Server

    Fiorenza, Domenico; Schreiber, Urs

    2016-01-01

    We compute the $L_\\infty$-theoretic dimensional reduction of the F1/D$p$-brane super $L_\\infty$-cocycles with coefficients in rationalized twisted K-theory from the 10d type IIA and type IIB super Lie algebras down to 9d. We show that the two resulting coefficient $L_\\infty$-algebras are naturally related by an $L_\\infty$-isomorphism which we find to act on the super $p$-brane cocycles by the infinitesimal version of the rules of topological T-duality and inducing an isomorphism between $K^0$ and $K^1$, rationally. Moreover, we show that these $L_\\infty$-algebras are the homotopy quotients of the RR-charge coefficients by the "T-duality Lie 2-algebra". We find that the induced $L_\\infty$-extension is a gerby extension of a 9+(1+1) dimensional (i.e. "doubled") T-duality correspondence super-spacetime, which serves as a local model for T-folds. We observe that this still extends, via the D0-brane cocycle of its type IIA factor, to a 10+(1+1)-dimensional super Lie algebra. Finally we observe that this satisfies ...

  6. SuperB Progress Reports - Physics

    CERN Document Server

    O'Leary, B.; Ramon, M.; Pous, E.; De Fazio, F.; Palano, A.; Eigen, G.; Asgeirsson, D.; Cheng, C.H.; Chivukula, A.; Echenard, B.; Hitlin, D.G.; Porter, F.; Rakitin, A.; Heinemeyer, S.; McElrath, B.; Andreassen, R.; Meadows, B.; Sokoloff, M.; Blanke, M.; Lesiak, T.; Shindou, T.; Ronga, F.; Baldini, W.; Bettoni, D.; Calabrese, R.; Cibinetto, G.; Luppi, E.; Rama, M.; Bossi, F.; Guido, E.; Patrignani, C.; Tosi, S.; Davies, C.; Lunghi, E.; Haisch, U.; Hurth, T.; Westhoff, S.; Crivellin, A.; Hofer, L.; Goto, T.; Brown, David Nathan; Branco, G.C.; Zupan, J.; Herrero, M.; Rodriguez-Sanchez, A.; Simi, G.; Tackmann, F.J.; Biassoni, P.; Lazzaro, A.; Lombardo, V.; Palombo, F.; Stracka, S.; Lindemann, D.M.; Robertson, S.H.; Duling, B.; Gemmler, K.; Gorbahn, M.; Jager, S.; Paradisi, P.; Straub, D.M.; Bigi, I.; Asner, D.M.; Fast, J.E.; Kouzes, R.T.; Morandin, M.; Rotondo, M.; Ben-Haim, E.; Arnaud, N.; Burmistrov, L.; Kou, E.; Perez, A.; Stocchi, A.; Viaud, B.; Domingo, F.; Piccinini, F.; Manoni, E.; Batignani, G.; Cervelli, A.; Forti, F.; Giorgi, M.; Lusiani, A.; Oberhof, B.; Paoloni, E.; Neri, N.; Walsh, J.; Bevan, A.; Bona, M.; Walker, C.; Weiland, C.; Lenz, A.; Gonzalez-Sprinberg, G.; Faccini, R.; Renga, F.; Polosa, A.; Silvestrini, L.; Virto, J.; Ciuchini, M.; Lubicz, V.; Tarantino, C.; Wilson, F.F.; Carpinelli, M.; Huber, T.; Mannel, T.; Graham, M.; Ratcliff, B.N.; Santoro, V.; Sekula, S.; Shougaev, K.; Soffer, A.; Shimizu, Y.; Gambino, P.; Mussa, R.; Nardecchia, M.; Stal, O.; Bernabeu, J.; Botella, F.; Jung, M.; Lopez March, N.; Martinez Vidal, F.; Oyanguren, A.; Pich, A.; Lozano, M.A.Sanchis; Vidal, J.; Vives, O.; Banerjee, S.; Roney, J.M.; Petrov, A.A.; Flood, K.

    2010-01-01

    SuperB is a high luminosity e+e- collider that will be able to indirectly probe new physics at energy scales far beyond the reach of any man made accelerator planned or in existence. Just as detailed understanding of the Standard Model of particle physics was developed from stringent constraints imposed by flavour changing processes between quarks, the detailed structure of any new physics is severely constrained by flavour processes. In order to elucidate this structure it is necessary to perform a number of complementary studies of a set of golden channels. With these measurements in hand, the pattern of deviations from the Standard Model behavior can be used as a test of the structure of new physics. If new physics is found at the LHC, then the many golden measurements from SuperB will help decode the subtle nature of the new physics. However if no new particles are found at the LHC, SuperB will be able to search for new physics at energy scales up to 10-100 TeV. In either scenario, flavour physics measure...

  7. Super Marx Generator for Thermonuclear Ignition

    CERN Document Server

    Winterberg, Friedwardt

    2008-01-01

    In ongoing electric pulse power driven inertial confinement fusion experiments, Marx generators are connected in parallel with the target in the center of a ring of the Marx generators. There the currents, not the voltages add up. Instead of connecting a bank of Marx generator in parallel, one may connect them in series, adding up their voltages, not the currents. If, for example, fifty 20 MV Marx generators are connected in series, they would add up to a gigavolt. But to prevent breakdown, the adding up of the voltages in such a super-Marx generator must be fast. For this reason, it is proposed that each of the Marx generators charges up a fast discharge capacitor, with the thusly charged fast capacitors becoming the elements of a second stage super Marx generator. In a super Marx generator, the Marx generators also assume the role of the resistors in the original Marx circuit. With a voltage of 10^9 Volt and a discharge current of 10^7 Ampere, the generation of a 10^16 Watt GeV proton beam becomes possible,...

  8. The SuperNEMO tracking detector

    CERN Document Server

    Cascella, M

    2015-01-01

    The SuperNEMO detector will search for neutrinoless double beta decay at the Modane Underground Laboratory on the French-Italian border. This decay mode, if observed, would be proof that the neutrino is its own antiparticle, would constitute evidence for total lepton number violation, and could allow a measurement of the absolute neutrino mass. The SuperNEMO experiment is designed to reach a half-life sensitivity of $10^{26}$ years corresponding to an effective Majorana neutrino mass of $50-100~$meV. The SuperNEMO detector design allows complete topological reconstruction of the double beta decay event enabling excellent levels of background rejection. In the event of a discovery, such topological measurements will be vital in determining the nature of the lepton number violating process. This reconstruction will be performed by a gaseous tracking detector, consisting of 2034 drift cells per module operated in Geiger mode. The tracker of the Demonstrator Module is currently under construction in the UK. This ...

  9. SuperB Technical Design Report

    CERN Document Server

    Baszczyk, M; Kolodziej, J; Kucewicz, W; Sapor, M; Jeremie, A; Pous, E Grauges; Bruno, G E; De Robertis, G; Diacono, D; Donvito, G; Fusco, P; Gargano, F; Giordano, F; Loddo, F; Loparco, F; Maggi, G P; Manzari, V; Mazziotta, M N; Nappi, E; Palano, A; Santeramo, B; Sgura, I; Silvestris, L; Spinoso, V; Eigen, G; Zalieckas, J; Zhuo, Z; Jenkovszky, L; Balbi, G; Boldini, M; Bonacorsi, D; Cafaro, V; D'Antone, I; Dallavalle, G M; Di Sipio, R; Fabbri, F; Fabbri, L; Gabrielli, A; Galli, D; Giacomelli, P; Giordano, V; Giorgi, F M; Grandi, C; Lax, I; Meo, S Lo; Marconi, U; Montanari, A; Pellegrini, G; Piccinini, M; Rovelli, T; Cesari, N Semprini; Torromeo, G; Tosi, N; Travaglini, R; Vagnoni, V M; Valentinetti, S; Villa, M; Zoccoli, A; Caron, J -F; Hearty, C; Lu, P F -T; Mattison, T S; McKenna, J A; So, R Y -C; Barnyakov, M Yu; Blinov, V E; Botov, A A; Druzhinin, V P; Golubev, V B; Kononov, S A; Kravchenko, E A; Levichev, E B; Onuchin, A P; Serednyakov, S I; Shtol, D A; Skovpen, Y I; Solodov, E P; Cardini, A; Carpinelli, M; Chao, D S -T; Cheng, C H; Doll, D A; Echenard, B; Flood, K; Hanson, J; Hitlin, D G; Ongmongkolkul, P; Porter, F C; Zhu, R Y; Randazzo, N; Burelo, E De La Cruz; Zheng, Y; Campos, P; De Silva, M; Kathirgamaraju, A; Meadows, B; Pushpawela, B; Shi, Y; Sokoloff, M; Castro, G Lopez; Ciaschini, V; Franchini, P; Giacomini, F; Paolini, A; Polania, G A Calderon; Laczek, S; Romanowicz, P; Szybinski, B; Czuchry, M; Flis, L; Harezlak, D; Kocot, J; Radecki, M; Sterzel, M; Szepieniec, T; Szymocha, T; Wójcik, P; Andreotti, M; Baldini, W; Calabrese, R; Carassiti, V; Cibinetto, G; Ramusino, A Cotta; Evangelisti, F; Gianoli, A; Luppi, E; Malaguti, R; Manzali, M; Melchiorri, M; Munerato, M; Padoan, C; Santoro, V; Tomassetti, L; Beretta, M M; Biagini, M; Boscolo, M; Capitolo, E; de Sangro, R; Esposito, M; Felici, G; Finocchiaro, G; Gatta, M; Gatti, C; Guiducci, S; Lauciani, S; Patteri, P; Peruzzi, I; Piccolo, M; Raimondi, P; Rama, M; Sanelli, C; Tomassini, S; Fabbricatore, P; Delepine, D; Santos, M A Reyes; Chrzaszcz, M; Grzymkowski, R; Knap, P; Kotula, J; Lesiak, T; Ludwin, J; Michalowski, J; Pawlik, B; Rachwal, B; Stodulski, M; Wiechczynski, J; Witek, M; Zawiejski, L; Zdybal, M; Aushev, V Y; Ustynov, A; Arnaud, N; Bambade, P; Beigbeder, C; Bogard, F; Borsato, M; Breton, D; Brossard, J; Burmistrov, L; Charlet, D; Chaumat, V; Dadoun, O; Berni, M El; Maalmi, J; Puill, V; Rimbault, C; Stocchi, A; Tocut, V; Variola, A; Wallon, S; Wormser, G; Grancagnolo, F; Ben-Haim, E; Sitt, S; Baylac, M; Bourrion, O; Deconto, J -M; Martinez, Y Gomez; Monseu, N; Muraz, J -F; Real, J -S; Vescovi, C; Cenci, R; Jawahery, A; Roberts, D; Twedt, E W; Cheaib, R; Lindemann, D; Nderitu, S; Patel, P; Robertson, S H; Swersky, D; Warburton, A; Flores, E Cuautle; Sanchez, G Toledo; Biassoni, P; Bombelli, L; Citterio, M; Coelli, S; Fiorini, C; Liberali, V; Monti, M; Nasri, B; Neri, N; Palombo, F; Sabatini, F; Stabile, A; Berra, A; Giachero, A; Gotti, C; Lietti, D; Maino, M; Pessina, G; Prest, M; Martin, J -P; Simard, M; Starinski, N; Taras, P; Drutskoy, A; Makarychev, S; Nefediev, A V; Aloisio, A; Cavaliere, S; De Nardo, G; Della Pietra, M; Doria, A; Giordano, R; Ordine, A; Pardi, S; Russo, G; Sciacca, C; Bigi, I I; Jessop, C P; Wang, W; Bellato, M; Benettoni, M; Corvo, M; Crescente, A; Corso, F Dal; Dosselli, U; Fanin, C; Gianelle, A; Longo, S; Michelotto, M; Montecassiano, F; Morandin, M; Pengo, R; Posocco, M; Rotondo, M; Simi, G; Stroili, R; Gaioni, L; Manazza, A; Manghisoni, M; Ratti, L; Re, V; Traversi, G; Zucca, S; Bizzaglia, S; Bizzarri, M; Cecchi, C; Germani, S; Lebeau, M; Lubrano, P; Manoni, E; Papi, A; Rossi, A; Scolieri, G; Batignani, G; Bettarini, S; Casarosa, G; Cervelli, A; Fella, A; Forti, F; Giorgi, M; Lilli, L; Lusiani, A; Oberhof, B; Paladino, A; Pantaleo, F; Paoloni, E; Perez, A L Perez; Rizzo, G; Walsh, J; Téllez, A Fernández; Beck, G; Berman, M; Bevan, A; Gannaway, F; Inguglia, G; Martin, A J; Morris, J; Bocci, V; Capodiferro, M; Chiodi, G; Dafinei, I; Drenska, N V; Faccini, R; Ferroni, F; Gargiulo, C; Gauzzi, P; Luci, C; Lunadei, R; Martellotti, G; Pellegrino, F; Pettinacci, V; Pinci, D; Recchia, L; Ruggeri, D; Zullo, A; Camarri, P; Cardarelli, R; De Santis, C; Di Ciaccio, A; Di Felice, V; Di Palma, F; Di Simone, A; Marcelli, L; Messi, R; Moricciani, D; Sparvoli, R; Tammaro, S; Branchini, P; Budano, A; Bussino, S; Ciuchini, M; Nguyen, F; Passeri, A; Ruggieri, F; Spiriti, E; Wilson, F; Monzon, I Leon; Millan-Almaraz, J R; Podesta-Lerma, P L M; Aston, D; Dey, B; Fisher, A; Jackson, P D; Leith, D W G S; Luitz, S; MacFarlane, D; McCulloch, M; Metcalfe, S; Novokhatski, A; Osier, S; Prepost, R; Ratcliff, B; Seeman, J; Sullivan, M; Va'vra, J; Wienands, U; Wisniewski, W; Altschul, B D; Purohit, M V; Baudot, J; Ripp-Baudot, I; Cirrone, G A P; Cuttone, G; Bezshyyko, O; Dolinska, G; Soffer, A; Bianchi, F; De Mori, F; Filippi, A; Gamba, D; Marcello, S; Bomben, M; Bosisio, L; Cristaudo, P; Lanceri, L; Liberti, B; Rashevskaya, I; Stella, C; Vallazza, E S; Vitale, L; Auriemma, G; Satriano, C; Vidal, F Martinez; de Cos, J Mazorra; Oyanguren, A; Valls, P Ruiz; Beaulieu, A; Dejong, S; Franta, J; Lewczuk, M J; Roney, M; Sobie, R

    2013-01-01

    In this Technical Design Report (TDR) we describe the SuperB detector that was to be installed on the SuperB e+e- high luminosity collider. The SuperB asymmetric collider, which was to be constructed on the Tor Vergata campus near the INFN Frascati National Laboratory, was designed to operate both at the Upsilon(4S) center-of-mass energy with a luminosity of 10^{36} cm^{-2}s^{-1} and at the tau/charm production threshold with a luminosity of 10^{35} cm^{-2}s^{-1}. This high luminosity, producing a data sample about a factor 100 larger than present B Factories, would allow investigation of new physics effects in rare decays, CP Violation and Lepton Flavour Violation. This document details the detector design presented in the Conceptual Design Report (CDR) in 2007. The R&D and engineering studies performed to arrive at the full detector design are described, and an updated cost estimate is presented. A combination of a more realistic cost estimates and the unavailability of funds due of the global economic ...

  10. Predicting the occurrence of super-storms

    Directory of Open Access Journals (Sweden)

    N. Srivastava

    2005-11-01

    Full Text Available A comparative study of five super-storms (Dst<-300 nT of the current solar cycle after the launch of SoHO, to identify solar and interplanetary variables that influence the magnitude of resulting geomagnetic storms, is described. Amongst solar variables, the initial speed of a CME is considered the most reliable predictor of the strength of the associated geomagnetic storm because fast mass ejections are responsible for building up the ram pressure at the Earth's magnetosphere. However, although most of the super-storms studied were associated with high speed CMEs, the Dst index of the resulting geomagnetic storms varied between -300 to -472 nT. The most intense storm of 20 November 2003, (Dst ~ -472 nT had its source in a comparatively smaller active region and was associated with a relatively weaker, M-class flare while all other super-storms had their origins in large active regions and were associated with strong X-class flares. However, this superstorm did not show any associated extraordinary solar and interplanetary characteristics. The study also reveals the challenge in the reliable prediction of the magnitude of a geomagnetic storm from solar and interplanetary variables.

  11. Funding for tuberculosis research-an urgent crisis of political will, human rights, and global solidarity.

    Science.gov (United States)

    Frick, Mike

    2017-03-01

    Tuberculosis (TB) killed more people in 2015 than any other single infectious agent, but funding for research to develop better prevention, diagnosis, and treatment methods for TB declined to its lowest level in 7 years. TB research and development (R&D) is woefully underfunded, a situation best viewed as a crisis of political will and a failure on the part of governments to see unmet innovation needs in the TB response as a human rights issue requiring immediate action. Over 60% of available money for TB R&D comes from public sources, and 67% of public money comes from a single country: the USA. The election of Donald Trump to the US presidency in November 2016 has introduced great uncertainty into the support that science generally, and TB research in particular, will receive in the coming years. Advocacy on the part of all actors-from civil society to TB-affected communities to scientists themselves-is urgently needed to increase US government support for TB research moving forward. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  12. Characteristics of motorcyclists involved in road traffic accidents attended at public urgent and emergency services.

    Science.gov (United States)

    Mascarenhas, Márcio Dênis Medeiros; Souto, Rayone Moreira Costa Veloso; Malta, Deborah Carvalho; Silva, Marta Maria Alves da; Lima, Cheila Marina de; Montenegro, Marli de Mesquita Silva

    2016-12-01

    Injuries resulting from motorcycle road traffic accidents are an important public health issue in Brazil. This study aimed to describe the characteristics of motorcyclists involved in traffic accidents attended in public urgent and emergency services in the state capitals and the Federal District. This is a cross-sectional study based on data from the Violence and Accident Surveillance System (VIVA Survey) in 2014. Data were analyzed according to sociodemographic, event and attendance characteristics. Proportional differences between genders were analyzed by chi-square test (Rao-Scott) with 5% significance level. Motorcyclist-related attendances (n = 9,673) reported a prevalence of men (gender ratio = 3.2), young people aged 20-39 years (65.7%), black / brown (73.6%), paid work (76.4%). Helmet use was reported by 79.1% of the victims, 13.3% had consumed alcohol in the six hours prior to the accident, 41.4% of the events were related to the victim's work. Accidents were more frequent on weekends, in the morning and late afternoon. These characteristics can support the development of public accident prevention policies and health promotion.

  13. A severe case of hemobilia and biliary fistula following an open urgent cholecystectomy

    Directory of Open Access Journals (Sweden)

    Del monaco Pamela

    2009-11-01

    Full Text Available Abstract Background Cholecystectomy has been the treatment of choice for symptomatic gallstones, but remains the greatest source of post-operative biliary injuries. Laparoscopic approach has been recently preferred because of short hospitalisation and low morbidity but has an higher incidence of biliary leakages and bile duct injuries than open one due to a technical error or misinterpretation of the anatomy. Even open cholecystectomy presents a small number of complications especially if it was performed in urgency. Hemobilia is one of the most common cause of upper gastrointestinal bleeding from the biliary ducts into the gastrointestinal tract due to trauma, advent of invasive procedures such as percutaneous liver biopsy, transhepatic cholangiography, and biliary drainage. Methods We report here a case of massive hemobilia in a 60-year-old man who underwent an urgent open cholecystectomy and a subsequent placement of a transhepatic biliary drainage. Conclusion The management of these complications enclose endoscopic, percutaneous and surgical therapies. After a diagnosis of biliary fistula, it's most important to assess the adequacy of bile drainage to determine a controlled fistula and to avoid bile collection and peritonitis. Transarterial embolization is the first line of intervention to stop hemobilia while surgical intervention should be considered if embolization fails or is contraindicated.

  14. Environmental Assessment of Urgent-Relief Acceptance of Foreign Research Reactor Spent Nuclear Fuel

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The Department of Energy has completed the Environmental Assessment (EA) of Urgent-Relief Acceptance of Foreign Research Reactor Spent Nuclear Fuel and issued a Finding of No Significant Impact (FONSI) for the proposed action. The EA and FONSI are enclosed for your information. The Department has decided to accept a limited number of spent nuclear fuel elements (409 elements) containing uranium that was enriched in the United States from eight research reactors in Austria, Denmark, Germany, Greece, the Netherlands, Sweden, and Switzerland. This action is necessary to maintain the viability of a major US nuclear weapons nonproliferation program to limit or eliminate the use of highly enriched uranium in civil programs. The purpose of the EA is to maintain the cooperation of the foreign research reactor operators with the nonproliferation program while a more extensive Environmental Impact Statement (EIS) is prepared on a proposed broader policy involving the acceptance of up to 15,000 foreign research reactor spent fuel elements over a 10 to 15 year period. Based on an evaluation of transport by commercial container liner or chartered vessel, five eastern seaboard ports, and truck and train modes of transporting the spent fuel overland to the Savannah River Sits, the Department has concluded that no significant impact would result from any combination of port and made of transport. In addition, no significant impacts were found from interim storage of spent fuel at the Savannah River Site.

  15. Patient-provider secure messaging in VA: variations in adoption and association with urgent care utilization.

    Science.gov (United States)

    Shimada, Stephanie L; Hogan, Timothy P; Rao, Sowmya R; Allison, Jeroan J; Quill, Ann L; Feng, Hua; Phillips, Barrett D; Nazi, Kim M; Haidary, Susan T; Houston, Thomas K

    2013-03-01

    The Veterans Health Administration has implemented patient to clinical team electronic asynchronous secure messaging (SM). This disruptive technology has the potential to support continuous, coordinated quality care, but limited evidence supports this connection. The objective of this paper is to (1) measure SM implementation and identify facility characteristics associated with higher rates of adoption and (2) understand the association of SM use and noncontinuity care [ie, urgent care (UC)] utilization rates. We conducted a retrospective cohort study of 132 VA facilities implementing SM in primary care. We used a combination of cross-sectional survey data on predictors of SM implementation and longitudinal data (July 2010-June 2012) on use of SM and UC. Human resources (coordinator and staff/volunteer availability to directly assist Veterans), computer resources (computers and computer rooms for Veterans), and leadership support for coordinators were associated with increased SM adoption rates. Higher SM use was associated with lower UC rates; early adopters of SM achieved a greater decrease in UC utilization over time than later adopters. In this exploratory analysis of early SM implementation in VA, we found a path of associations linking SM and reductions in UC utilization. These results suggest a need for further examination of the relationship between SM and its effects on health care utilization patterns.

  16. Research and increase of expertise in arachno-entomology are urgently needed.

    Science.gov (United States)

    Mehlhorn, Heinz; Al-Rasheid, Khaled A S; Al-Quraishy, Saleh; Abdel-Ghaffar, Fathy

    2012-01-01

    Considering the contents of international journals of parasitology dealing with broader topics inside this field show that rather a few papers appear with studies in the discipline of arachno-entomology. In the journals Journal of Parasitology, Parasitology Research and Trends in Parasitology, the relations of published papers on protozoology, helminthology and arachno-entomology showed that in all three journals, papers on protozoans were the most common, while those on helminths of any kind reached the second place being rather as common as the protozoan papers in Parasitology Research and in the Journal of Parasitology. In Trends of Parasitology, however, the papers on helminths reached only about 25% of the numbers published on protozoan topics. But in all three journals-and this is important-the papers on arachno-entomological themes were scarce reaching less than the half of the protozoan papers in Parasitology Research, and only about 15% in the Journal of Parasitology and in the Trends of Parasitology. These disproportions between the three great subdivisions of targets in the focus of parasitological research are dangerous, since this lack exists already for several decades and thus led to a backlog of unsolved increasing problems that are caused by ticks, mites, insects and/or parasitic crustaceans especially in times of intensive globalization and global warming. Studies on the biology, vectorship, invasion and spreading of wanted vectors and on the control of pests and parasites belonging to the field of arachno-entomology are urgently needed.

  17. Health literacy in the urgent care setting: What factors impact consumer comprehension of health information?

    Science.gov (United States)

    Alberti, Traci L; Morris, Nancy J

    2017-05-01

    An increasing number of Americans are using urgent care (UC) clinics due to: improved health insurance coverage, the need to decrease cost, primary care offices with limited appointment availability, and a desire for convenient care. Patients are treated by providers they may not know for episodic illness or injuries while in pain or not feeling well. Treatment instructions and follow-up directions are provided quickly. To examine health literacy in the adult UC population and identify patient characteristics associated with health literacy risk. As part of a larger cross-sectional study, UC patients seen between October 2013 and January 2014 completed a demographic questionnaire and the Newest Vital Sign. Descriptive, nonparametric analyses, and a multinomial logistic regression were done to assess health literacy, associated and predictive factors. A total of 57.5% of 285 participants had adequate health literacy. The likelihood of limited health literacy was associated with increased age (p literacy is common in a suburban UC setting, increasing the risk that consumers may not understand vital health information. Clear provider communication and confirmation of comprehension of discharge instructions for self-management is essential to optimize outcomes for UC patients. ©2017 American Association of Nurse Practitioners.

  18. An urgent need to understand and address the safety and well-being of hospital "sitters".

    Science.gov (United States)

    Schoenfisch, Ashley L; Pompeii, Lisa A; Lipscomb, Hester J; Smith, Claudia D; Upadhyaya, Mudita; Dement, John M

    2015-12-01

    Hospital sitters provide continuous observation of patients at risk of harming themselves or others. Little is known about sitters' occupational safety and well-being, including experiences with patient/visitor-perpetrated violence (type II). Data from surveys, focus groups, individual interviews at six U.S. hospitals were used to characterize the prevalence of and circumstance surrounding type II violence against sitters, as well as broader issues related to sitter use. Sitter respondents had a high 12-month prevalence of physical assault, physical threat, and verbal abuse compared to other workers in the hospital setting. Sitters and other staff indicated the need for clarification of sitters' roles regarding patient care and sitter well-being (e.g., calling for assistance, taking lunch/restroom breaks), training of sitters in personal safety and de-escalation, methods to communicate patient/visitor behaviors, and unit-level support. The burden of type II violence against hospital sitters is concerning. Policies surrounding sitters' roles and violence prevention training are urgently needed. © 2015 Wiley Periodicals, Inc.

  19. URGENT DESTABILIZERS OF PUBLIC AND STATE SECURITY, TACTICS OF COUNTERACTION TO IT

    Directory of Open Access Journals (Sweden)

    D. N. Marinkin

    2016-01-01

    Full Text Available At creation of civil society in any constitutional state there is a crime counteraction problem. In the modern Russian Federation safety problems from the negative social phenomena and processes force scientists, public agents and ordinary citizens to investigate constantly such determinants and the reasons (destabilizers of safety of society and the constitutional state, to eliminate their consequences. Such problems as are urgent now: increase in information on ways and consequences of violence in the mass media (MM, the Internet, computer games, traditional physical abuse. The number of questions and assessment by citizens of consequences of the conducted terrorist attacks and infringement of life of citizens causes. The accounting of the specified problems and versions of decisions in law-enforcement practice, will allow to promote as a result efficiency of prevention of offenses and crimes and will bring closer modern Russia to ideal model of the constitutional state with real civil society. In article the author designates a number of the legal and social destabilizers of safety existing now in the Russian society and the state, proposes the solution of their negative impact on society within tactics of crime control.

  20. Newly discovered reefs in the southern Abrolhos Bank, Brazil: Anthropogenic impacts and urgent conservation needs.

    Science.gov (United States)

    Mazzei, E F; Bertoncini, A A; Pinheiro, H T; Machado, L F; Vilar, C C; Guabiroba, H C; Costa, T J F; Bueno, L S; Santos, L N; Francini-Filho, R B; Hostim-Silva, M; Joyeux, J-C

    2017-01-15

    The Abrolhos Bank is an area of high ecological, socio-economic importance and harbour the richest and most-extensive coral reefs in the South Atlantic. Here we report the discovery of shallow (12-25m depth) reef complex with ten large biogenic structures, intermediate between the typical mushroom-shaped pinnacles of the northern Abrolhos Bank (17°-18° S) and the small patch reefs found on the central/southern coast of the Espírito Santo State (19°-20° S). The newly discovered reefs harbour a relatively rich and abundant reef community, with 73 fish and 14 benthic cnidarian species, including endangered and commercially important ones. We discuss on urgent needs of properly mapping and understanding the ecological functioning of this reef system. Information provided here is a baseline for future impact evaluations, particularly considering the recent worst environmental disaster of Brazil from a dam collapse in Doce river that affected the region. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Cyborg practices: call-handlers and computerised decision support systems in urgent and emergency care.

    Science.gov (United States)

    Pope, Catherine; Halford, Susan; Turnbull, Joanne; Prichard, Jane

    2014-06-01

    This article draws on data collected during a 2-year project examining the deployment of a computerised decision support system. This computerised decision support system was designed to be used by non-clinical staff for dealing with calls to emergency (999) and urgent care (out-of-hours) services. One of the promises of computerised decisions support technologies is that they can 'hold' vast amounts of sophisticated clinical knowledge and combine it with decision algorithms to enable standardised decision-making by non-clinical (clerical) staff. This article draws on our ethnographic study of this computerised decision support system in use, and we use our analysis to question the 'automated' vision of decision-making in healthcare call-handling. We show that embodied and experiential (human) expertise remains central and highly salient in this work, and we propose that the deployment of the computerised decision support system creates something new, that this conjunction of computer and human creates a cyborg practice.

  2. Funding for tuberculosis research—an urgent crisis of political will, human rights, and global solidarity

    Directory of Open Access Journals (Sweden)

    Mike Frick

    2017-03-01

    Full Text Available Tuberculosis (TB killed more people in 2015 than any other single infectious agent, but funding for research to develop better prevention, diagnosis, and treatment methods for TB declined to its lowest level in 7 years. TB research and development (R&D is woefully underfunded, a situation best viewed as a crisis of political will and a failure on the part of governments to see unmet innovation needs in the TB response as a human rights issue requiring immediate action. Over 60% of available money for TB R&D comes from public sources, and 67% of public money comes from a single country: the USA. The election of Donald Trump to the US presidency in November 2016 has introduced great uncertainty into the support that science generally, and TB research in particular, will receive in the coming years. Advocacy on the part of all actors—from civil society to TB-affected communities to scientists themselves—is urgently needed to increase US government support for TB research moving forward.

  3. Accidental falls in urgent and emergency care: results of the 2014 VIVA Survey.

    Science.gov (United States)

    Ribeiro, Adalgisa Peixoto; Souza, Edinilsa Ramos de; Sousa, Carlos Augusto Moreira de; Freitas, Mariana Gonçalves de

    2016-12-01

    This cross-sectional study aimed to analyze the cases of falls in urgent and emergency care services of 24 Brazilian capitals and the Federal District participating in the 2014 VIVA Survey. We sought to describe the epidemiological profile of victims, characterizing the event and the severity of injuries it caused and to perform an association study. We calculated the simple and relative frequencies of variables and performed multivariate logistic regression analysis for complex sample data in order to verify associations between falls and selected variables. Fall victims profile results show a predominance of males, age groups 0-9years and 20-39 years and brown skin. Outcomes show that 56% fell from own height, public road was the most frequent place of falls and 92.7% of people receiving care for falls suffered some kind of injury, of which most common were bruises, sprain and strains, followed by cut/laceration. In the final model, we were able to associate fall with gender, age, education, disability and place of the event. The likelihood of falls at school is 14% higher than at home, but falls in recreation areas, public roads and other places are less likely than at home.

  4. Staff perceptions on patient motives for attending GP-led urgent care centres in London: a qualitative study.

    Science.gov (United States)

    Greenfield, Geva; Ignatowicz, Agnieszka; Gnani, Shamini; Bucktowonsing, Medhavi; Ladbrooke, Tim; Millington, Hugh; Car, Josip; Majeed, Azeem

    2016-01-14

    General practitioner (GP)-led urgent care centres were established to meet the growing demand for urgent care. Staff members working in such centres are central in influencing patients' choices about which services they use, but little is known about staff perceptions of patients' motives for attending urgent care. We hence aimed to explore their perceptions of patients' motives for attending such centres. A phenomenological, qualitative study, including semistructured interviews. The interviews were analysed using thematic content analysis. 2 GP-led urgent care centres in 2 academic hospitals in London. 15 staff members working at the centres including 8 GPs, 5 emergency nurse practitioners and 2 receptionists. We identified 4 main themes: 'Confusion about choices', 'As if increase of appetite had grown; By what it fed on', 'Overt reasons, covert motives' and 'A question of legitimacy'. The participants thought that the centres introduce convenient and fast access for patients. So convenient, that an increasing number of patients use them as a regular alternative to their community GP. The participants perceived that patients attend the centres because they are anxious about their symptoms and view them as serious, cannot get an appointment with their GP quickly and conveniently, are dissatisfied with the GP, or lack self-care skills. Staff members perceived some motives as legitimate (an acute health need and difficulties in getting an appointment), and others as less legitimate (convenience, minor illness, and seeking quicker access to hospital facilities). The participants perceived that patients attend urgent care centres because of the convenience of access relative to primary care, as well as sense of acuity and anxiety, lack self-care skills and other reasons. They perceived some motives as more legitimate than others. Attention to unmet needs in primary care can help in promoting balanced access to urgent care. Published by the BMJ Publishing Group Limited

  5. Split liver transplantation benefits the recipient of the 'leftover liver'.

    Science.gov (United States)

    Dunn, S P; Haynes, J H; Nicolette, L A; Falkenstein, K; Pierson, A; Billmire, D F; Vinocur, C D; Weintraub, W

    1997-02-01

    The division of a single hepatic allograft to create two reduced-size grafts has been reported with decreased graft survival (50%) resulting in decreased enthusiasm for this approach. The authors reviewed their experience with 12 recipients of this procedure to evaluate the outcome of the children electively undergoing transplant with the "leftover liver." A retrospective review of six pairs of children receiving part of one hepatic allograft included donor anatomy, recipient operation, and allograft and patient outcomes. Recipient pairs were selected according to blood type compatibility, medical priority, and size restrictions of the larger right lobe and the smaller left lateral segment. Patient and graft survival were compared with elective and urgent patients undergoing whole or reduced-size transplants. Six donors weighed 71.8 +/- 17.4 kg and were 22.6 +/- 11.0 years of age. Recipients of the right lobe were 11.8 +/- 4.2 years of age and weighed 41.9 +/- 14 kg. Recipients of the left lateral segment were 1.81 +/- 1.1 years of age and weighed 9.85 +/- 1.82 kg. Six patients were initially offered the donor allograft because of their hospitalization, critical illness or waiting time. Six additional patients electively underwent transplantation with the leftover liver. Donor organs were screened for normal arterial anatomy. Division of the allograft was performed on the back table in the falciform groove. Generally the left lateral segment graft received the major portion of the hepatic artery and the right lobe the major portion of the portal vein. Five of six (83%) elective patients, two receiving the right lobe and three receiving the left lateral segment had prompt recovery and left the hospital without surgical complication. One recipient of a right lobe transplant died from primary allograft nonfunction. These results are not different from the outcomes of all elective patients who underwent transplantation with whole or reduced-sized transplants in the

  6. Super-Resolution Imaging on Microfluidic Super-Resolution Near-Field Structure

    Institute of Scientific and Technical Information of China (English)

    WANG Pei; TANG Lin; ZHANG Dou-Guo; LU Yong-Hua; JIAO Xiao-Jin; XIE Jian-Ping; MING Hai

    2005-01-01

    @@ We present a new concept of the microfluidic super-resolution near-field structure (MSRENS) based on a microfluidic structure and a super-resolution near-field structure. The near-field distance control, "nano-probe"and scanning can be realized simultaneously using the MSRENS, which is similar to a near-field scanning optical microscope. The design and simulation results are presented. Numerical simulation has demonstrated that the MSRENS with spatial resolution beyond the diffraction limit could be applicable in chemistry, biologics, and many other fields.

  7. SuperB: An opportunity to study baryons with beauty and bottom super-nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Feliciello, A., E-mail: Alessandro.Feliciello@to.infn.it [Istituto Nazionale di Fisica Nucleare, Sezione di Torino, Via P. Giuria 1, I-10125 Torino (Italy)

    2012-05-01

    SuperB is an INFN flagship project for a new high-luminosity heavy-flavor factory. Along with its companion detector, it is dedicated to the search for CP violation effects in the B meson sector with the aim of looking for direct and indirect signals of new physics, beyond the Standard Model. However it could offer as well the opportunity for a systematic, high-statistics study of b baryon properties and for a search for bottom super-nuclei, that is bound nuclear systems with an explicit content of beauty.

  8. RESEARCH NOTES On the support of super-Brownian motion with super-Brownian immigration

    Institute of Scientific and Technical Information of China (English)

    洪文明; 钟惠芳

    2001-01-01

    The support properties of the super Brownian motion with random immigration Xρ1 are considered,where the immigration rate is governed by the trajectory of another super-Brownian motion ρ. When both the initial state Xρo of the process and the immigration rate process ρo are of finite measure and with compact supports, the probability of the support of the process Xρi dominated by a ball is given by the solutions of a singular elliptic boundary value problem.

  9. Super-hybrid composites - An emerging structural material

    Science.gov (United States)

    Chamis, C. C.; Lark, R. F.; Sullivan, T. L.

    1975-01-01

    Specimens of super-hybrids and advanced fiber composites were subjected to extensive tests to determine their mechanical properties, including impact and thermal fatigue. The super-hybrids were fabricated by a procedure similar to that reported by Chamis et al., (1975). Super-hybrids subjected to 1000 cycles of thermal fatigue from -100 to 300 F retained over 90% of their longitudinal flexural strength and over 75% of their transverse flexural strength; their transverse flexural strength may be as high as 8 times that of a commercially supplied boron/1100-Al composite. The thin specimen Izod longitudinal impact resistance of the super-hybrids was twice that of the boron/110-Al material. Super-hybrids subjected to transverse tensile loads exhibited nonlinear stress-strain relationships. The experimentally determined initial membrane (in-plane) and bending elastic properties of super-hybrids were predicted adequately by linear laminate analysis.

  10. Why Do People Choose Emergency and Urgent Care Services? A Rapid Review Utilizing a Systematic Literature Search and Narrative Synthesis.

    Science.gov (United States)

    Coster, Joanne E; Turner, Janette K; Bradbury, Daniel; Cantrell, Anna

    2017-09-01

    Rising demand for emergency and urgent care services is well documented, as are the consequences, for example, emergency department (ED) crowding, increased costs, pressure on services, and waiting times. Multiple factors have been suggested to explain why demand is increasing, including an aging population, rising number of people with multiple chronic conditions, and behavioral changes relating to how people choose to access health services. The aim of this systematic mapping review was to bring together published research from urgent and emergency care settings to identify drivers that underpin patient decisions to access urgent and emergency care. Systematic searches were conducted across Medline (via Ovid SP), EMBASE (via Ovid), The Cochrane Library (via Wiley Online Library), Web of Science (via the Web of Knowledge), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; via EBSCOhost). Peer-reviewed studies written in English that reported reasons for accessing or choosing emergency or urgent care services and were published between 1995 and 2016 were included. Data were extracted and reasons for choosing emergency and urgent care were identified and mapped. Thematic analysis was used to identify themes and findings were reported qualitatively using framework-based narrative synthesis. Thirty-eight studies were identified that met the inclusion criteria. Most studies were set in the United Kingdom (39.4%) or the United States (34.2%) and reported results relating to ED (68.4%). Thirty-nine percent of studies utilized qualitative or mixed research designs. Our thematic analysis identified six broad themes that summarized reasons why patients chose to access ED or urgent care. These were access to and confidence in primary care; perceived urgency, anxiety, and the value of reassurance from emergency-based services; views of family, friends, or healthcare professionals; convenience (location, not having to make appointment, and opening hours

  11. Cirurgia colorectal urgente: modelos de morbimortalidade cirúrgica no adulto oncológico idoso e muito idoso

    OpenAIRE

    GOMES,A.; Batista, H.; Sousa, M; Rocha, R.; Marinho, R.; Carneiro, C.; Pignatelli, N.; Nunes, V

    2013-01-01

    INTRODUÇÃO: A população idosa que recorre ao Serviço de Urgência tem vindo a aumentar. É uma população com características fisiopatológicas específicas que coloca dilemas sobre o risco/benefício da cirurgia urgente. OBJECTIVOS: Comparar os scores P-POSSUM, CR-POSSUM e ACPGBI enquanto modelos de morbimortalidade cirúrgica nos idosos e muito idosos submetidos a cirurgia coloretal urgente por doença maligna. MATERIAL E MÉTODOS: Estudo longitudinal retrospectivo. Foram incluídos doentes c...

  12. Mallas profilácticas en laparotomía urgente. Resultados a largo plazo en un estudio retrospectivo.

    OpenAIRE

    2013-01-01

    El objetivo de nuestro estudio fue determinar la eficacia y seguridad del uso de mallas sintéticas profilácticas en laparotomías urgentes para la prevención de hernia incisional y evisceración. Planteamos un estudio retrospectivo de datos informatizados de 266 pacientes sometidos a laparotomía media urgente durante dos años. Se analizaon las complicaciones postoperatorias y la incidencia de hernia incisional según el tipo de cierre de pared. Podemos concluir que el uso de malla profiláctica s...

  13. Being a non-urgent patient in an emergency care unit--a strive to maintain personal integrity.

    Science.gov (United States)

    Nyström, Maria; Nydén, Kristoffer; Petersson, Martin

    2003-01-01

    The aim of this study was to analyse and describe experiences of being a non-urgent patient in an ECU (emergency care unit). Eleven non-urgent patients were interviewed. The research approach was inductive and interpretative. Seven tentative interpretations and an interpreted whole, i.e., an existential interpretation, revealed that the informants tried to be 'good' patients by not demanding much attention from nursing personnel, in an attempt to maintain good relations with the nurses in order to be assured of a positive reception. As health related problems jeopardize personal integrity, patients cannot afford the risk of being looked upon as inappropriate clients in the ECU.

  14. Heart-Lung Transplantation

    Science.gov (United States)

    Griffith, Bartley P.

    1987-01-01

    The survival rate (average, 50%) of patients undergoing cardiopulmonary transplantation falls well below that expected for cardiac transplantation alone. We give a broad overview of the various grounds upon which this difference is likely based and discuss recent advances in each area: 1) criteria for the selection of candidates and donors, 2) methods for ex-vivo preservation of donor organs, 3) technical execution of the operative procedure, and 4) prevention of postoperative infection. In connection with the prevention of postoperative infection, we discuss the potential for the development of a chronic obliterative disease that, once established, has proved inexorable. Current efforts are focused on detection when the process is in an early, reversible stage, and on research into causation. (Texas Heart Institute Journal 1987; 14:364-368) Images PMID:15227291

  15. On Super Edge-Antimagicness of Subdivided Stars

    Directory of Open Access Journals (Sweden)

    Raheem A.

    2015-11-01

    Full Text Available Enomoto, Llado, Nakamigawa and Ringel (1998 defined the concept of a super (a, 0-edge-antimagic total labeling and proposed the conjecture that every tree is a super (a, 0-edge-antimagic total graph. In the support of this conjecture, the present paper deals with different results on super (a, d-edge-antimagic total labeling of subdivided stars for d ∈ {0, 1, 2, 3}.

  16. Super-resolution optical telescopes with local light diffraction shrinkage

    OpenAIRE

    Changtao Wang; Dongliang Tang; Yanqin Wang; Zeyu Zhao; Jiong Wang; Mingbo Pu; Yudong Zhang; Wei Yan; Ping Gao; Xiangang Luo

    2015-01-01

    Suffering from giant size of objective lenses and infeasible manipulations of distant targets, telescopes could not seek helps from present super-resolution imaging, such as scanning near-field optical microscopy, perfect lens and stimulated emission depletion microscopy. In this paper, local light diffraction shrinkage associated with optical super-oscillatory phenomenon is proposed for real-time and optically restoring super-resolution imaging information in a telescope system. It is found ...

  17. The Robotic Super-LOTIS Telescope: Results & Future Plans

    OpenAIRE

    Williams, G. G.; Milne, P. A.; Park, H.S.; Barthelmy, S. D.; Hartmann, D. H.; Updike, A.; Hurley, K.

    2008-01-01

    We provide an overview of the robotic Super-LOTIS (Livermore Optical Transient Imaging System) telescope and present results from gamma-ray burst (GRB) afterglow observations using Super-LOTIS and other Steward Observatory telescopes. The 0.6-m Super-LOTIS telescope is a fully robotic system dedicated to the measurement of prompt and early time optical emission from GRBs. The system began routine operations from its Steward Observatory site atop Kitt Peak in April 2000 and currently operates ...

  18. Trasplante pulmonar Lung transplant

    Directory of Open Access Journals (Sweden)

    M. Espinosa

    2006-08-01

    Full Text Available El transplante pulmonar suele ser la última opción terapéutica para pacientes con insuficiencia respiratoria. A pesar de los muchos avances en inmunología y el manejo de las complicaciones, la mortalidad y morbilidad asociadas a este trasplante son muy superiores a los demás. El rechazo agudo es casi un problema universal en el primer año, mientras que la bronquiolitis obliterante limita la supervivencia a largo plazo. Las infecciones respiratorias también cumplen un papel importante en las complicaciones asociadas al trasplante pulmonar por la constante exposición del injerto al medio exterior. No obstante, los éxitos de esta opción terapéutica que depende fundamentalmente de una correcta selección de donante y receptor, son evidentes, sobre todo en cuanto a calidad de vida se refiere.A lung transplant is usually the final therapeutic option for patients with respiratory insufficiency. In spite of the many advances in immunology and the management of complications, mortality and morbidity associated with this transplant are far higher than with others. Acute rejection is an almost universal problem in the first year, while obliterative bronchitis reduces long term survival. Respiratory infections also play a significant role in the complications associated with lung transplants due to the constant exposure of the graft to the outside. However, the success of this therapeutic option, which basically depends on a suitable selection of donor and recipient, are evident, above all with respect to quality of life.

  19. Heart-lung transplantation

    OpenAIRE

    Griffith, Bartley P.; Magliato, Kathy E.

    2014-01-01

    Heart-lung transplantation itself is not a particularly difficult operation technically. It is the setting in which this procedure is performed which is difficult. The three issues of importance in a successful outcome are appropriate harvest of the heart-lung bloc from the donor, careful explant of the heart and lungs of the recipient, and finally the implant of the heart-lung bloc into the recipient. None of this requires extraordinary technical skill, but does require careful coordination ...

  20. Vitamin therapy after heart transplantation.

    Science.gov (United States)

    Patel, Jignesh

    2015-10-01

    The need for routine nutritional supplementation with vitamins in most healthy individuals remains a matter of debate and current guidelines recommend that the need for these essential nutrients be met primarily through consuming an adequate diet. However, after heart transplantation, multiple factors, including the effects of prolonged debilitation prior to surgery and immunosuppression, may lead to physiological stress, which may justify consideration for vitamin supplementation. In general, clinical trials have not focused on vitamin supplementation after heart transplantation. There appears to be some limited clinical data to support the use of certain vitamins after heart transplantation. In particular, the putative antioxidant properties of vitamins C and E after heart transplantation may be beneficial as prophylaxis against cardiac allograft vasculopathy, and vitamin D, in conjunction with calcium, may help prevent post-transplant bone loss. Current guidelines only address the use of vitamin D after heart transplantation.

  1. Dialysis and transplantation in Sudan.

    Science.gov (United States)

    Suliman, S M; Beliela, M H; Hamza, H

    1995-01-01

    In this report we present the current status of the renal replacement therapy in Sudan. Sudan is a large country with 30 million inhabitants. Peritoneal Dialysis was started in 1968, while hemodialysis was started in 1973. At present, there are only 16 hemodialysis machines serving 56 patients in two centers in Sudan. There are also 15 peritoneal dialysis beds for 70 intermittent peritoneal dialysis patients in three centers. Continuous ambulatory peritoneal dialysis is not being practiced in Sudan. The first renal transplant was in 1974, and till now more than 30 transplants have been performed in two transplant centers. All the transplants have been from living donors. The scholars of Islam in Sudan oppose to donation from cadavers. There are 200 renal transplant patients being followed up in Sudan and the majority had their renal transplants abroad. We conclude that there is a tremendous shortage of renal services in Sudan. There are more efforts being made to improve these services.

  2. Autologous Bone Marrow Stromal Cell Transplantation for Central Nervous System Disorders – Recent Progress and Perspective for Clinical Application

    Directory of Open Access Journals (Sweden)

    Kuroda S

    2011-01-01

    Full Text Available There is increasing evidence that the transplanted BMSC significantly promote functional recovery after CNS damage in the animal models of various kinds of CNS disorders, including cerebral infarct, traumatic brain injury and spinal cord injury. However, there are several shortages of information when considering clinical application of BMSC transplantation for patients with CNS disorders. In this review, therefore, we discuss what we should clarify to establish cell transplantation therapy as the scientifically proven entity in clinical situation and describe our recent works for this purpose. The BMSC have the ability to alter their gene expression profile and phenotype in response to the surrounding circumstances and to protect the neurons by producing some neurotrophic factors. They also promote neurite extension and rebuild the neural circuits in the injured CNS. The BMSC can be expanded in vitro using the animal serum-free medium. Pharmacological modulation may accelerate the in vitro proliferation of the BMSC. Using in vivo optical imaging technique, the transplanted BMSC can non-invasively be tracked in the living animals for at least 8 weeks after transplantation. It is urgent issues to develop clinical imaging technique to track the transplanted cells in the CNS and evaluate the therapeutic significance of BMSC transplantation in order to establish it as a definite therapeutic strategy in clinical situation in the future.

  3. Pregnancy and renal transplantation.

    Science.gov (United States)

    Başaran, O; Emiroğlu, R; Seçme, S; Moray, G; Haberal, M

    2004-01-01

    Ovarian dysfunction, anovulatory vaginal bleeding, amenorrhea, high prolactin levels, and loss of libido are the causes of infertility in women with chronic renal failure. After renal transplantation, endocrine function generally improves after recovery of renal function. In this study we retrospectively evaluated the prepregnancy and postdelivery renal function, outcome of gestation, as well as maternal and fetal complications for eight pregnancies in eight renal transplant recipients between November 1975 and March 2003 of 1095 among 1425. Eight planned pregnancies occurred at a mean of 3.6 years posttransplant. Spontaneous abortion occured in the first trimester in one case. One intrauterine growth retardation was observed with a full-term pregnancy; one intrauterine growth retardation and preterm delivery; one preeclampsia with preterm delivery and urinary tract infection; and one preeclampsia with preterm delivery and oligohydramnios. The mean gestation period was 35.5 +/- 3.0 weeks (31.2 to 38.0). Pregnancy had no negative impact on renal function during a 2-year follow-up. No significant proteinuria or acute rejection episodes were observed. Among the seven deliveries, no congenital anomaly was documented and no postpartum problems for the child and the mother were observed. Our study suggests that successful pregnancy is possible in renal transplant recipients. In cases with good graft function and absence of severe proteinuria or hypertension, pregnancy does not affect graft function or patient survival; however, fetal problems are encountered such as intrauterine growth retardation, low birth weight, and preeclampsia.

  4. Spin groups of super metrics and a theorem of Rogers

    Science.gov (United States)

    Fulp, Ronald

    2017-01-01

    We derive the canonical forms of super Riemannian metrics and the local isometry groups of such metrics. For certain super metrics we also compute the simply connected covering groups of the local isometry groups and interpret these as local spin groups of the super metric. Super metrics define reductions OSg of the relevant frame bundle. When principal bundles S˜g exist with structure group the simply connected covering group G ˜ of the structure group of OSg , representations of G ˜ define vector bundles associated to S˜g whose sections are "spinor fields" associated with the super metric g . Using a generalization of a Theorem of Rogers, which is itself one of the main results of this paper, we show that for super metrics we call body reducible, each such simply connected covering group G ˜ is a super Lie group with a conventional super Lie algebra as its corresponding super Lie algebra. Some of our results were known to DeWitt (1984) using formal Grassmann series and others were known by Rogers using finitely many Grassmann generators and passing to a direct limit. We work exclusively in the category of G∞ supermanifolds with G∞ mappings. Our supernumbers are infinite series of products of Grassmann generators subject to convergence in the ℓ1 norm introduced by Rogers (1980, 2007).

  5. New Results from Super-K and K2K

    CERN Document Server

    Wilkes, R J

    2002-01-01

    This paper summarizes recent (as of SSI-02, in some cases updated in November, 2002) results from the Super-Kamiokande and K2K experiments. The interpretation of Super-Kamiokande results on atmospheric and solar neutrinos provides strong evidence for neutrino oscillations, hence non-zero neutrino mass. While statistics are still limited, K2K data are consistent with Super-Kamiokande results on neutrino oscillations. The effort to reconstruct Super-Kamiokande following a cascade of phototube implosions in November, 2001 is described. Plans for the future are also discussed.

  6. Video super-resolution using simultaneous motion and intensity calculations

    DEFF Research Database (Denmark)

    Keller, Sune Høgild; Lauze, Francois Bernard; Nielsen, Mads

    2011-01-01

    for the joint estimation of a super-resolution sequence and its flow field. Via the calculus of variations, this leads to a coupled system of partial differential equations for image sequence and motion estimation. We solve a simplified form of this system and as a by-product we indeed provide a motion field...... for super-resolved sequences. Computing super-resolved flows has to our knowledge not been done before. Most advanced super-resolution (SR) methods found in literature cannot be applied to general video with arbitrary scene content and/or arbitrary optical flows, as it is possible with our simultaneous VSR...

  7. Transplantation of female genital organs.

    Science.gov (United States)

    Brännström, Mats; Díaz-García, César

    2011-04-01

    Transplantation of gynecological organs is a medical field where considerable advancements have been made in research during the last 25 years and with some procedures already introduced as clinical treatments. These types of transplantations aim at curing permanent infertility. Uterus transplantation has been proven to be a feasible procedure in different experimentation animal models with proof of concept concerning surgery, control of rejection and fertility. There has already been one human transplantation attempt, which, however, was unsuccessful. Based on the progress in this area, we predict that the first successful uterus transplantation attempt will come within 2-3 years. Orthotopic ovarian cortex transplantation has overcome the status of an experimental procedure since more than 20 pregnancies have been reported. Its main field of application is fertility preservation in oncologic patients undergoing high gonadotoxic risk therapies. The role of heterotopic ovarian cortex transplantation still remains at the research level, although co-transplantation with an orthotopic cortex might facilitate a more accurate endocrine environment. The major drawback of ovarian cortex transplantation remains the long ischemic interval between re-implantation and the establishment of neovascularization. Whole ovary cryopreservation followed by transplantation through vascular anastomosis may emerge as an important procedure in this field, because the warm ischemic time would be reduced from several days to less than 1 h, which will most likely improve follicle survival. In summary, transplantation surgery is also entering the field of gynecology and in the future several types of transplantations of organs/tissues of the female reproductive tract may become established clinical procedures.

  8. Cardiac transplantation in Friedreich ataxia.

    Science.gov (United States)

    Yoon, Grace; Soman, Teesta; Wilson, Judith; George, Kristen; Mital, Seema; Dipchand, Anne I; McCabe, Jane; Logan, William; Kantor, Paul

    2012-09-01

    In this article, we describe a 14-year-old boy with a confirmed diagnosis of Friedreich ataxia who underwent cardiac transplantation for left ventricular failure secondary to dilated cardiomyopathy with restrictive physiology. His neurological status prior to transplantation reflected early signs of neurological disease, with evidence of dysarthria, weakness, mild gait impairment, and limb ataxia. We review the ethical issues considered during the process leading to the decision to offer cardiac transplantation.

  9. [The history of kidney transplantation].

    Science.gov (United States)

    Hatzinger, M; Stastny, M; Grützmacher, P; Sohn, M

    2016-10-01

    The history of kidney transplantation is a history of many unsuccessful efforts and setbacks, but also the history of perseverance, pioneering spirit, and steadfast courage. The first successful transplantation of a dog kidney was done by the Austrian Emerich Ullmann (1861-1937) in 1902. The kidney was connected to the carotid artery of the dog and the ureter ended freely. The organ produced urine for a couple of days before it died. In 1909, there were efforts to transplant human kidneys from deceased patients to monkeys and in the following year the first xenotransplantation in humans was completed. Different kinds of donors were tried: dogs, monkeys, goats and lambs, all without success. In 1939, the first transplantation from a deceased human donor was done by the Russion Yurii Voronoy, the patient survived for only a couple of days, and the organ never worked. In 1953, the first temporarily successful transplantation of a human kidney was performed by Jean Hamburger in Paris. A 16-year-old boy received the kidney of his mother as living donor transplantation. Then in 1954, a milestone was made with the first long-term successful kidney transplantation by Joseph Murray: the transplantation was done between monozygotic twins; the organ survived for 8 years. For his efforts in kidney transplantation, Murray was honored with the Nobel Prize in medicine in 1990. In 1962, the first kidney transplantation between genetically nonrelated patients was done using immunosuppression and in 1963 the first kidney transplantation in Germany was done by Reinhard Nagel and Wilhelm Brosig in Berlin. The aim of this article is to present the history of kidney transplantation from the beginning until today.

  10. El Mapa de la Incapacidad en España una necesidad urgente

    Directory of Open Access Journals (Sweden)

    Araceli López-Guillén García

    2015-09-01

    Full Text Available Resumen: Es urgente adaptar los sistemas de recogida de datos en incapacidad laboral para conseguir una mejor explotación epidemiológica de los mismos que facilite conocer la situación, análisis y planificación estratégica sobre incapacidad, creando con una base de datos mínimos básicos el Mapa de la Incapacidad en España permitiendo conocer las causas y el impacto de las situaciones de incapacidad laboral, practicar una gestión integral de recursos, prevenir las situaciones de incapacidad laboral, potenciar los mecanismos de detección de la enfermedad y los aspectos preventivos de la salud laboral, mejorar la gestión sanitaria que precisa y la protección socio laboral. Conclusiones: Proponemos la base mínima de datos para la elaborar el Mapa de Incapacidad. Conociendo el impacto incapacitante de la pérdida de salud en la población trabajadora se procederá a una mejor gestión y adecuación de recursos atencionales, promocionales, preventivos, reintegradores, y prestacionales en torno a la incapacidad temporal y permanente. Conocer nuestra población "incapacitada (por enfermedad" es fundamental para cualquier análisis sobre impacto y necesidades de protección social, para contrastarla con la población activa, la población en formación o inactiva previa a la edad laboral, y la población inactiva jubilada.

  11. Effects of implementation of an urgent surgical care service on subspecialty general surgery training

    Science.gov (United States)

    Wood, Leanne; Buczkowski, Andrzej; Panton, Ormond M.N.; Sidhu, Ravi S.; Hameed, S. Morad

    2010-01-01

    Background In July 2007, a large Canadian teaching hospital realigned its general surgery services into elective general surgery subspecialty-based services (SUBS) and a new urgent surgical care (USC) service (also know in the literature as an acute care surgery service). The residents on SUBS had their number of on-call days reduced to enable them to focus on activities related to SUBS. Our aim was to examine the effect of the creation of the USC service on the educational experiences of SUBS residents. Methods We enrolled residents who were on SUBS for the 6 months before and after the introduction of the USC service. We collected data by use of a survey, WEB eVAL and recorded attendance at academic half days. Our 2 primary outcomes were residents’ attendance at ambulatory clinics and compliance with the reduction in the number of on-call days. Our secondary outcomes included residents’ time for independent study, attendance at academic half days, operative experience, attendance at multidisciplinary rounds and overall satisfaction with SUBS. Results Residents on SUBS had a decrease in the mean number of on-call days per resident per month from 6.28 to 1.84 (p = 0.006), an increase in mean attendance at academic half days from 65% to 87% (p = 0.028), at multidisciplinary rounds (p = 0.002) and at ambulatory clinics and an increase in independent reading time (p = 0.015), and they reported an improvement in their work environment. There was no change in the amount of time residents spent in the operating room or in their overall satisfaction with SUBS. Conclusion Residents’ education in the SUBS structure was positively affected by the creation of a USC service. Compliance with the readjustment of on-call duties was high and was identified as the single most significant factor in enabling residents to take full advantage of the unique educational opportunities available only while on SUBS. PMID:20334744

  12. Psychopathology of the General Population Referred by Primary Care Physicians for Urgent Assessment in Psychiatric Hospitals

    Directory of Open Access Journals (Sweden)

    Judith McLenan

    2016-12-01

    Full Text Available Objective: The aim of this study was to evaluate the type, severity and progression of psychiatric pathologies in a sample of 372 outpatients (age range 18–65 years referred by their primary general practitioners (GPs to an Urgent Referral Team (URT based in a psychiatric hospital in Aberdeen, Scotland. This team offers immediate appointments (1- to 7-day delays for rapid assessments and early interventions to the outpatients referred by their primary family doctors.Method: One-sample t-test and z statistic were used for data analysis. From the total population, a convenience sample of 40 people was selected and assessed to evaluate whether follow-up appointments after the first visit could reduce the severity of suicidal ideation, depression and anxiety in the outpatients seen by the URT. A two-sample t-test and a Wilcoxon signed-rank test were used to assess the variations in the scores during the follow-up visits.Results: We found a statistically significant prevalence of depressive disorders, comorbid with anxiety at first presentation in people who were females, white, never married, living with a partner, not studying and not in paid employment. The common presentation of borderline personality disorder and dysthymia in this population underscores its vulnerability to major socioeconomic challenges.Conclusion: The data confirmed the impact that primary care cooperation with psychiatric hospitals can have on the psychiatric system, and as a reflection, on the population’s mental health and well-being. In fact, active cooperation and early diagnosis and intervention will help detect cases at risk in the general population and reduce admissions into hospitals.

  13. Types of Cancer Associated with Transplant Recipients

    Science.gov (United States)

    ... an option. Switching immunosuppression from a calcineurin inhibitor ( Cyclosporine , Tacrolimus ) to a Target-of-Rapamycin (TOR) inhibitor ( ... Douglas W. Post-Transplant De Novo Malignancies in Renal Transplant Recipients: The ... International 2006. Transplantation 70:1747-51, 2000. First ...

  14. Uterus transplantation: on the edge.

    Science.gov (United States)

    Del Priore, Giuseppe; Schlatt, Stefan; Wagner, Robert; Reynoso, Elena; Malanowska-Stega, Jeanetta

    2011-01-01

    Uterus transplantation for absolute uterus factor infertility is moving closer to human trials. The indication for uterus transplantation is evident as is its potential to ameliorate the social and personal burdens of these patients. The extensive collaborative research efforts between animal works, advancements in transplantation medicine, and immune suppression have culminated in demonstrating its apparent feasibility. As for the concerns regarding its risk, in perspective it is similar to other high-risk pregnancies. Moving uterus transplantation toward clinical applications obviously will require a continued commitment of research and support.

  15. Ethical considerations in face transplantation.

    Science.gov (United States)

    Brown, Charles S; Gander, Brian; Cunningham, Michael; Furr, Allen; Vasilic, Dalibor; Wiggins, Osborne; Banis, Joseph C; Vossen, Marieke; Maldonado, Claudio; Perez-Abadia, Gustavo; Barker, John H

    2007-10-01

    Human face transplantation is now a clinical reality. The surgical techniques necessary to perform these procedures have been used routinely in reconstructive microsurgery for many years. From an immunological standpoint since face and hand contain mostly the same tissues it is reasonable to assume that the same immunosuppressive regimen found to be effective in human hand transplants should also work in face transplantation. It is the ethical issues associated with the risks and benefits of performing facial transplantation that have posed the greatest challenges leading up to performing this new procedure. In this editorial, we will review some of the main events that have led to the recently performed human face transplants, specifically focusing on the key ethical issues at the center of this debate. We will discuss how the research and clinical experience in human hand transplantation laid the foundation for performing face transplantation and describe the research and the ethical guidelines upon which a team at the University of Louisville based their position "to move ahead" in spite of much criticism. Finally we will outline some of the key arguments against face transplantation, and conclude with a discussion on what comes next now that the first human face transplants have been performed.

  16. Trasplante renal Kidney transplant

    Directory of Open Access Journals (Sweden)

    P. Martín

    2006-08-01

    Full Text Available El trasplante renal es la terapia de elección para la mayoría de las causas de insuficiencia renal crónica terminal porque mejora la calidad de vida y la supervivencia frente a la diálisis. El trasplante renal de donante vivo es una excelente alternativa para el paciente joven en situación de prediálisis porque ofrece mejores resultados. El tratamiento inmunosupresor debe ser individualizado buscando la sinergia inmunosupresora y el mejor perfil de seguridad, y debe adaptarse a las diferentes etapas del trasplante renal. En el seguimiento del trasplante renal hay que tener muy en cuenta los factores de riesgo cardiovascular y los tumores puesto que la muerte del paciente con injerto funcionante es la segunda causa de pérdida del injerto tras el primer año del trasplante. La función alterada del injerto es un factor de mortalidad cardiovascular independiente que requerirá seguimiento y control de todas sus complicaciones para retrasar la entrada en diálisis.The kidney transplant is the therapy of choice for the majority of the causes of chronic terminal kidney insufficiency, because it improves the quality of life and survival in comparison with dialysis. A kidney transplant from a live donor is an excellent alternative for the young patient in a state of pre-dialysis because it offers the best results. Immunosuppressive treatment must be individualised, seeking immunosuppressive synergy and the best safety profile, and must be adapted to the different stages of the kidney transplant. In the follow-up to the kidney transplant, cardiovascular risk factors and tumours must be especially taken into account, given that the death of the patient with a working graft is the second cause of loss of the graft following the first year of the transplant. The altered function of the graft is a factor of independent cardiovascular mortality that will require follow-up and the control of all its complications to postpone the entrance in dialysis.

  17. Super-Hamiltonian Structures and Conservation Laws of a New Six-Component Super-Ablowitz-Kaup-Newell-Segur Hierarchy

    Directory of Open Access Journals (Sweden)

    Fucai You

    2014-01-01

    Full Text Available A six-component super-Ablowitz-Kaup-Newell-Segur (-AKNS hierarchy is proposed by the zero curvature equation associated with Lie superalgebras. Supertrace identity is used to furnish the super-Hamiltonian structures for the resulting nonlinear superintegrable hierarchy. Furthermore, we derive the infinite conservation laws of the first two nonlinear super-AKNS equations in the hierarchy by utilizing spectral parameter expansions. PACS: 02.30.Ik; 02.30.Jr; 02.20.Sv.

  18. Super-Liouville - Double Liouville correspondence

    CERN Document Server

    Hadasz, Leszek

    2014-01-01

    The AGT motivated relation between the tensor product of the N=1 super-Liouville field theory with the imaginary free fermion (SL) and a certain projected tensor products of the real and the imaginary Liouville field theories (LL) is analyzed. Using conformal field theory techniques we give a complete proof of the equivalence in the NS sector. It is shown that SL-LL correspondence is based on the equivalence of chiral objects including suitably chosen chiral structure constants of all three Liouville theories involved.

  19. A Trio of Super-Earths

    Science.gov (United States)

    2008-06-01

    Today, at an international conference, a team of European astronomers announced a remarkable breakthrough in the field of extra-solar planets. Using the HARPS instrument at the ESO La Silla Observatory, they have found a triple system of super-Earths around the star HD 40307. Moreover, looking at their entire sample studied with HARPS, the astronomers count a total of 45 candidate planets with a mass below 30 Earth masses and an orbital period shorter than 50 days. This implies that one solar-like star out of three harbours such planets. A trio of Super-Earths ESO PR Photo 19a/08 A trio of Super-Earths "Does every single star harbour planets and, if yes, how many?" wonders planet hunter Michel Mayor from Geneva Observatory. "We may not yet know the answer but we are making huge progress towards it." Since the discovery in 1995 of a planet around the star 51 Pegasi by Mayor and Didier Queloz, more than 270 exoplanets have been found, mostly around solar-like stars. Most of these planets are giants, such as Jupiter or Saturn, and current statistics show that about 1 out of 14 stars harbours this kind of planet. "With the advent of much more precise instruments such as the HARPS spectrograph on ESO's 3.6-m telescope at La Silla, we can now discover smaller planets, with masses between 2 and 10 times the Earth's mass," says Stéphane Udry, one of Mayor's colleagues. Such planets are called super-Earths, as they are more massive than the Earth but less massive than Uranus and Neptune (about 15 Earth masses). The group of astronomers have now discovered a system of three super-Earths around a rather normal star, which is slightly less massive than our Sun, and is located 42 light-years away towards the southern Doradus and Pictor constellations. "We have made very precise measurements of the velocity of the star HD 40307 over the last five years, which clearly reveal the presence of three planets," says Mayor. The planets, having 4.2, 6.7, and 9.4 times the mass of the

  20. SuperLU users' guide

    Energy Technology Data Exchange (ETDEWEB)

    Demmel, James W.; Gilbert, John R.; Li, Xiaoye S.

    1999-11-01

    This document describes a collection of three related ANSI C subroutine libraries for solving sparse linear systems of equations AX = B: Here A is a square, nonsingular, n x n sparse matrix, and X and B are dense n x nrhs matrices, where nrhs is the number of right-hand sides and solution vectors. Matrix A need not be symmetric or definite; indeed, SuperLU is particularly appropriate for matrices with very unsymmetric structure. All three libraries use variations of Gaussian elimination optimized to take advantage both of sparsity and the computer architecture, in particular memory hierarchies (caches) and parallelism.

  1. Production of super-smooth articles

    Energy Technology Data Exchange (ETDEWEB)

    Duchane, D.V.

    1981-05-29

    Super-smooth rounded or formed articles made of thermoplastic materials including various poly(methyl methacrylate) or acrylonitrile-butadiene-styrene copolymers are produced by immersing the articles into a bath, the composition of which is slowly changed with time. The starting composition of the bath is made up of at least one solvent for the polymer and a diluent made up of at least one nonsolvent for the polymer and optional materials which are soluble in the bath. The resulting extremely smooth articles are useful as mandrels for laser fusion and should be useful for a wide variety of other purposes, for example lenses.

  2. Emergent Super-Virasoro on Magnetic Branes

    CERN Document Server

    D'Hoker, Eric

    2016-01-01

    The low energy limit of the stress tensor, gauge current, and supercurrent two-point correlators are calculated in the background of the supersymmetric magnetic brane solution to gauged five-dimensional supergravity constructed by Almuhairi and Polchinski. The resulting correlators provide evidence for the emergence of an N=2 super-Virasoro algebra of right-movers, in addition to a bosonic Virasoro algebra and a $U(1) \\oplus U(1)$-current algebra of left-movers (or the parity transform of left- and right-movers depending on the sign of the magnetic field), in the holographically dual strongly interacting two-dimensional effective field theory of the lowest Landau level.

  3. Super-utilizers get red carpet treatment.

    Science.gov (United States)

    2014-01-01

    MetroHealth Medical Center in Cleveland has partnered with two health plans to provide intensive care coordination for high-cost patients with multiple medical problems and, often, behavioral health issues. Nurse practitioners at two primary care sites provide one-on-one care coordination for super-utilizers. They assess the patients' needs, help coordinate community resources, and prepare a treatment plan that is flagged when patients visit the emergency department. The nurse practitioners meet with health plan representatives monthly and brainstorm on ways to meet patients' needs.

  4. The Super-B Project Accelerator Status

    Energy Technology Data Exchange (ETDEWEB)

    Biagini, M.E.; Alesini, D.; Boni, R.; Boscolo, M.; Demma, T.; Drago, A.; Esposito, M.; Guiducci, S.; Marcellini, F.; Mazzitelli, G.; Preger, M.; Raimondi, P.; Sanelli, C.; Serio, M.; Stecchi, A.; Stella, A.; Tomassini, S.; Zobov, M.; /Frascati; Bertsche, K.; Brachmann, A.; Cai, Y.; /SLAC /Novosibirsk, IYF /Annecy, LAPP /LPSC, Grenoble /Orsay, LAL /Saclay /Pisa U. /CERN

    2011-08-17

    The SuperB project is an international effort aiming at building in Italy a very high luminosity e{sup +}e{sup -} (10{sup 36} cm{sup -2} sec{sup -1}) asymmetric collider at the Y(4S) energy in the CM. The accelerator design has been extensively studied and changed during the past year. The present design, based on the new collision scheme, with large Piwinski angle and the use of 'crab waist' sextupoles already successfully tested at the DA{Phi}NE {Phi}-Factory at LNF Frascati, provides larger flexibility, better dynamic aperture and spin manipulation sections in the Low Energy Ring (LER) for longitudinal polarization of the electron beam at the Interaction Point (IP). The Interaction Region (IR) has been further optimized in terms of apertures and reduced backgrounds in the detector. The injector complex design has been also updated. A summary of the project status will be presented in this paper. The SuperB collider can reach a peak luminosity of 10{sup 36} cm{sup -2} sec{sup -1} with beam currents and bunch lengths similar to those of the past and present e{sup +}e{sup -} Factories, through the use of smaller emittances and new scheme of crossing angle collision. The beams are stored in two rings at 6.7 GeV (HER) and 4.2 GeV (LER). Unique features of the project are the polarization of the electron beam in the LER and the possibility to decrease the energies for running at the {tau}/charm threshold. The option to reuse the PEP-II B-Factory (SLAC) hardware will allow reducing costs. The SuperB facility will require a big complex of civil infrastructure. The main construction, which will house the final part of the LINAC, the injection lines, the damping rings, and the storage rings, will be mainly underground. Two sites have been considered: the campus of Tor Vergata University near Frascati, and the INFN Frascati Laboratory. No decision has been made yet. A footprint of the possible SuperB layout on the LNF area is shown in Fig. 1.

  5. Super computer made with Linux cluster

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Hun; Oh, Yeong Eun; Kim, Jeong Seok

    2002-01-15

    This book consists of twelve chapters, which introduce super computer made with Linux cluster. The contents of this book are Linux cluster, the principle of cluster, design of Linux cluster, general things for Linux, building up terminal server and client, Bear wolf cluster by Debian GNU/Linux, cluster system with red hat, Monitoring system, application programming-MPI, on set-up and install application programming-PVM, with PVM programming and XPVM application programming-open PBS with composition and install and set-up and GRID with GRID system, GSI, GRAM, MDS, its install and using of tool kit.

  6. Transfer function characteristics of super resolving systems

    Science.gov (United States)

    Milster, Tom D.; Curtis, Craig H.

    1992-01-01

    Signal quality in an optical storage device greatly depends on the optical system transfer function used to write and read data patterns. The problem is similar to analysis of scanning optical microscopes. Hopkins and Braat have analyzed write-once-read-many (WORM) optical data storage devices. Herein, transfer function analysis of magnetooptic (MO) data storage devices is discussed with respect to improving transfer-function characteristics. Several authors have described improving the transfer function as super resolution. However, none have thoroughly analyzed the MO optical system and effects of the medium. Both the optical system transfer function and effects of the medium of this development are discussed.

  7. Medical care at the Super Bowl.

    Science.gov (United States)

    Ellis, J M

    2000-06-01

    Although coordinating medical care at the Super Bowl is something that we look forward to and have a lot of fun doing, we take it very seriously and understand the importance of delivering medical care at what many people consider to be the greatest sporting event in the world. It is certainly one of the most watched and recognized events in the world and because of this, we attempt to set up a system that will allow for the best medical care available and standardization of this medical care through our experience within Medical Sports Group.

  8. New challenge of tuberculosis control in shanghai;urgent need to help internal migrants in the period of economic transition

    Institute of Scientific and Technical Information of China (English)

    Zhan Shaokang; Liu xiaoyun; Tang Shenglan; Squire S B; Zheng Ni

    2003-01-01

    @@ RATIONALE: Increasing internal migration from rural areas to cities in the period of economic transition in China has lead to changes in disease pattern and health service provision, including tuberculosis control. Tuberculosis control in migrants, being one forth population in Shanghai, is very important and urgent.

  9. 76 FR 14269 - Unexpected Urgent Refugee and Migration Needs Related to C[ocirc]te d'Ivoire

    Science.gov (United States)

    2011-03-16

    ... Register. (Presidential Sig.) THE WHITE HOUSE, Washington, March 7, 2011 [FR Doc. 2011-6257 Filed 3-15-11... Unexpected Urgent Refugee and Migration Needs Related to C te d'Ivoire Memorandum for the Secretary of State..., including section 2(c)(1) of the Migration and Refugee Assistance Act of 1962 (the ``Act''), as amended,...

  10. 75 FR 34617 - Unexpected Urgent Refugee and Migration Needs Related to Somalia and Food Pipeline Breaks for...

    Science.gov (United States)

    2010-06-18

    ... Federal Register. (Presidential Sig.) THE WHITE HOUSE, Washington, June 8, 2010. [FR Doc. 2010-14879 Filed... Unexpected Urgent Refugee and Migration Needs Related to Somalia and Food Pipeline Breaks for Refugee and... Migration and Refugee Assistance Act of 1962 (the ``Act''), as amended, (22 U.S.C.2601), I hereby...

  11. [Budget impact analysis of idarucizumab for the management of patients treated with dabigatran in emergency / urgent situations in Italy

    Directory of Open Access Journals (Sweden)

    Andrea Belisari

    2016-06-01

    CONCLUSION: Idarucizumab for the management of patients treated with dabigatran in emergency / urgent situations has the potential for substantial savings, compared to treatments currently available. This preliminary assessment will require further confirmatory evidence when the product will become available in Italian healthcare setting. [Article in Italian

  12. Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

    NARCIS (Netherlands)

    K.E. Holt (Kathryn E.); H.F.L. Wertheim (Heiman); R.N. Zadoks (Ruth N.); S. Baker (Stephen); C.A. Whitehouse (Chris A.); D. Dance (David); A. Jenney (Adam); T.R. Connor (Thomas R.); L.Y. Hsu (Li Yang); J.A. Severin (Juliëtte); S. Brisse; H. Cao (Hanwei); J. Wilksch (Jonathan); C. Gorrie (Claire); M.B. Schultz (Mark B.); D.J. Edwards (David J.); K. Van Nguyen (Kinh); T.V. Nguyen (Trung Vu); T.T. Dao (Trinh Tuyet); M. Mensink (Martijn); V. Le Minh (Vien); N.T.K. Nhu (Nguyen Thi Khanh); C. Schultsz (Constance); K. Kuntaman (Kuntaman); P.N. Newton (Paul N.); C.E. Moore (Catrin E.); R.A. Strugnell (Richard A.); N.R. Thomson (Nicholas R.)

    2015-01-01

    textabstractKlebsiella pneumoniae is nowrecognized as an urgent threat to human health because of the emergence of multidrug-resistant strains associated with hospital outbreaks and hypervirulent strains associated with severe community-acquired infections. K. pneumoniae is ubiquitous in the

  13. Knowledge production connected to the social construction of the Urgent Project System in Sharp Co. : Revisiting social constructionism

    OpenAIRE

    Kanai, Toshihiro; Matsushima, Noboru; Urano, Mitsuhiro

    2012-01-01

    In this article, we propose that the scientific knowledge has a public nature. Our knowledge production, therefore, is inevitably connected to the realities socially constructed. We discuss how our knowledge production is connected to the management practices, according to our field research of the urgent project system in Sharp Co..

  14. Serologic vaccination response after solid organ transplantation: a systematic review.

    Directory of Open Access Journals (Sweden)

    Isabella Eckerle

    Full Text Available BACKGROUND: Infectious diseases after solid organ transplantation (SOT are one of the major complications in transplantation medicine. Vaccination-based prevention is desirable, but data on the response to active vaccination after SOT are conflicting. METHODS: In this systematic review, we identify the serologic response rate of SOT recipients to post-transplantation vaccination against tetanus, diphtheria, polio, hepatitis A and B, influenza, Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitides, tick-borne encephalitis, rabies, varicella, mumps, measles, and rubella. RESULTS: Of the 2478 papers initially identified, 72 were included in the final review. The most important findings are that (1 most clinical trials conducted and published over more than 30 years have all been small and highly heterogeneous regarding trial design, patient cohorts selected, patient inclusion criteria, dosing and vaccination schemes, follow up periods and outcomes assessed, (2 the individual vaccines investigated have been studied predominately only in one group of SOT recipients, i.e. tetanus, diphtheria and polio in RTX recipients, hepatitis A exclusively in adult LTX recipients and mumps, measles and rubella in paediatric LTX recipients, (3 SOT recipients mount an immune response which is for most vaccines lower than in healthy controls. The degree to which this response is impaired varies with the type of vaccine, age and organ transplanted and (4 for some vaccines antibodies decline rapidly. CONCLUSION: Vaccine-based prevention of infectious diseases is far from satisfactory in SOT recipients. Despite the large number of vaccination studies preformed over the past decades, knowledge on vaccination response is still limited. Even though the protection, which can be achieved in SOT recipients through vaccination, appears encouraging on the basis of available data, current vaccination guidelines and recommendations for post-SOT recipients

  15. Post-transplant lymphoproliferative disorder following kidney transplantation

    DEFF Research Database (Denmark)

    Maksten, Eva Futtrup; Vase, Maja Ølholm; Kampmann, Jan;

    2016-01-01

    to identify possible PTLDs. Candidate PTLDs underwent histopathological review and classification. Seventy PTLD cases were identified in 2175 transplantations (3.2%). The incidence rate (IR) after first transplantation was 5.4 cases per 1000 patient-years (95% CI: 4.0-7.3). Most PTLDs were monomorphic (58...

  16. Transplant tourism in China: a tale of two transplants.

    Science.gov (United States)

    Rhodes, Rosamond; Schiano, Thomas

    2010-02-01

    The use of organs obtained from executed prisoners in China has recently been condemned by every major transplant organization. The government of the People's Republic of China has also recently made it illegal to provide transplant organs from executed prisoners to foreigners transplant tourists. Nevertheless, the extreme shortage of transplant organs in the U.S. continues to make organ transplantation in China an appealing option for some patients with end-stage disease. Their choice of traveling to China for an organ leaves U.S. transplant programs with decisions about how to respond to the needs of patients who return after transplantation. By discussing two cases that raised this dilemma, we argue for upholding medicine's commitments to traditional principles of beneficence and nonjudgmental regard in sorting out the policies that a transplant program should adopt. We also explain how position statements that aim for the high ground of moral purity fail to give appropriate weight to the needs and suffering of present and future patients in the U.S. and in China.

  17. Split-liver transplantation : An underused resource in liver transplantation

    NARCIS (Netherlands)

    Rogiers, Xavier; Sieders, Egbert

    2008-01-01

    Split-liver transplantation is an efficient tool to increase the number of liver grafts available for transplantation. More than 15 years after its introduction only the classical splitting technique has reached broad application. Consequently children are benefiting most from this possibility. Full

  18. Pediatric Liver Transplantation: Our Experiences

    Science.gov (United States)

    Basturk, Ahmet; Yılmaz, Aygen; Sayar, Ersin; Dinçhan, Ayhan; Aliosmanoğlu, İbrahim; Erbiş, Halil; Aydınlı, Bülent; Artan, Reha

    2016-01-01

    Objective: The aim of our study was to evaluate our liver transplant pediatric patients and to report our experience in the complications and the long-term follow-up results. Materials and Methods: Patients between the ages of 0 and 18 years, who had liver transplantation in the organ transplantation center of our university hospital between 1997 and 2016, were included in the study. The age, sex, indications for the liver transplantation, complications after the transplantation, and long-term follow-up findings were retrospectively evaluated. The obtained results were analyzed with statistical methods. Results: In our organ transplantation center, 62 pediatric liver transplantations were carried out since 1997. The mean age of our patients was 7.3 years (6.5 months–17 years). The 4 most common reasons for liver transplantation were: Wilson’s disease (n=10; 16.3%), biliary atresia (n=9; 14.5%), progressive familial intrahepatic cholestasis (n=8; 12.9%), and cryptogenic cirrhosis (n=7; 11.3%). The mortality rate after transplantation was 19.6% (12 of the total 62 patients). The observed acute and chronic rejection rates were 34% and 4.9%, respectively. Thrombosis (9.6%) was observed in the hepatic artery (4.8%) and portal vein (4.8%). Bile leakage and biliary stricture rates were 31% and 11%, respectively. 1-year and 5-year survival rates of our patients were 87% and 84%, respectively. Conclusion: The morbidity and mortality rates in our organ transplantation center, regarding pediatric liver transplantations, are consistent with the literature. PMID:28149148

  19. Conductas urgentes y evaluativas en función del nivel de riesgo en situaciones de conducción

    Directory of Open Access Journals (Sweden)

    Alberto Megías

    2013-10-01

    Full Text Available Las situaciones de riesgo en conducción requieren, en la mayoría de las ocasiones, una decisión de carácter urgente, distinguiéndose de lo que se ajustaría más a una conducta evaluativa que podría llevar a cabo un observador. Para explorar la diferenciación entre conductas evaluativas y urgentes, e intentar estudiar bajo qué condiciones pueden producirse, se diseñó una escala de riesgo subjetivo basada en una taxonomía de situaciones de riesgo en conducción. Este estudio refleja una falta de relación directa entre la evaluación de la situación y la decisión comportamental con carácter urgente que demanda dicha situación. Las conductas urgentes obtuvieron respuestas más conservadoras y diferencias en tiempos de reacción dependiendo del nivel de riesgo de la situación, lo cual abre la posibilidad de que nuestras conductas no se adapten exclusivamente a nuestra evaluación. Las diferencias encontradas pueden ser explicadas en base a los rasgos de la tarea en función del nivel de riesgo que conlleva la situación. Estos datos pueden ser una buena base para el diseño de futuros programas de educación vial y formación de conductores, centrados en el aprendizaje y entrenamiento a través de la ejecución de conductas urgentes.

  20. The need for xenotransplantation as a source of organs and cells for clinical transplantation.

    Science.gov (United States)

    Ekser, Burcin; Cooper, David K C; Tector, A Joseph

    2015-11-01

    The limited availability of deceased human organs and cells for the purposes of clinical transplantation remains critical worldwide. Despite the increasing utilization of 'high-risk', 'marginal', or 'extended criteria' deceased donors, in the U.S. each day 30 patients either die or are removed from the waiting list because they become too sick to undergo organ transplantation. In certain other countries, where there is cultural resistance to deceased donation, e.g., Japan, the increased utilization of living donors, e.g., of a single kidney or partial liver, only very partially addresses the organ shortage. For transplants of tissues and cells, e.g., pancreatic islet transplantation for patients with diabetes, and corneal transplantation for patients with corneal blindness (whose numbers worldwide are potentially in the millions), allotransplantation will never prove a sufficient source. There is an urgent need for an alternative source of organs and cells. The pig could prove to be a satisfactory source, and clinical xenotransplantation using pig organs or cells, particularly with the advantages provided by genetic engineering to provide resistance to the human immune response, may resolve the organ shortage. The physiologic compatibilities and incompatibilities of the pig and the human are briefly reviewed.

  1. Nonmyeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia.

    Science.gov (United States)

    Clay, Jennifer; Kulasekararaj, Austin G; Potter, Victoria; Grimaldi, Francesco; McLornan, Donal; Raj, Kavita; de Lavallade, Hugues; Kenyon, Michelle; Pagliuca, Antonio; Mufti, Ghulam J; Marsh, Judith C W

    2014-11-01

    New transplant approaches are urgently needed for patients with refractory severe aplastic anemia (SAA) who lack a matched sibling or unrelated donor (UD) or who have failed UD or cord blood transplant. Patients with refractory SAA are at risk of later clonal evolution to myelodysplastic syndrome and acute leukemia. We report our pilot findings with haploidentical hematopoietic stem cell transplantation (haploHSCT) using uniform reduced-intensity conditioning with postgraft high-dose cyclophosphamide in 8 patients with refractory SAA or patients who rejected a prior UD or cord blood transplant. Six of 8 patients engrafted. Graft failure was associated with donor-directed HLA antibodies, despite intensive pre-HSCT desensitization with plasma exchange and rituximab. There was only 1 case of grade II skin graft-versus-host disease. We show that haploHSCT can successfully rescue refractory SAA patients who lack donor-directed HLA antibodies but not in the presence of donor-directed HLA antibodies. This novel protocol for haploHSCT for SAA has been adopted by the European Group for Blood and Marrow Transplantation Severe Aplastic Anaemia Working Party for a future noninterventional, observational study to further evaluate its efficacy.

  2. Subclinical peritonitis due to perforated sigmoid diverticulitis 14 years after heart-lung transplantation

    Institute of Scientific and Technical Information of China (English)

    Haridimos Markogiannakis; Manousos Konstadoulakis; Dimitrios Tzertzemelis; Pantelis Antonakis; Ilias Gomatos; Constantinos Bramis; Andreas Manouras

    2008-01-01

    Acute complicated diverticulitis, particularly with colon perforation, is a rare but serious condition in transplant recipients with high morbidity and mortality. Neither acute diverticulitis nor colon perforation has been reported in young heart-lung grafted patients. A case of subclinical peritonitis due to perforated acute sigmoid diverticulitis 14 years after heart-lung transplantation is reported. A 26-year-old woman, who received heart-lung transplantation 14 years ago, presented with vague abdominal pain. Physical examination was normal. Blood tests revealed leukocytosis. Abdominal X-ray showed air-fluid levels while CT demonstrated peritonitis due to perforated sigmoid diverticulitis. Sigmoidectomy and end colostomy (Hartmann's procedure) were performed. Histopathology confirmed perforated acute sigmoid diverticulitis. The patient was discharged on the 8th postoperative day after an uneventful postoperative course. This is the first report of acute diverticulitis resulting in colon perforation in a young heart-lung transplanted patient. Clinical presentation, even in peritonitis, may be atypical due to the masking effects of immunosuppression. A high index of suspicion, urgent aggressive diagnostic investigation of even vague abdominal symptoms, adjustment of immunosuppression, broad-spectrum antibiotics, and immediate surgical treatment are critical. Moreover, strategies to reduce the risk of this complication should be implemented. Pretransplantation colon screening, prophylactic pretransplantation sigmoid resection in patients with diverticulosis, and elective surgical intervention in patients with nonoperatively treated acute diverticulitis after transplantation deserve consideration and further studies.

  3. Urgent percutaneous coronary intervention leads to a decrease in serum concentrations of soluble CD40 ligand

    Directory of Open Access Journals (Sweden)

    Ratković Nenad

    2010-01-01

    Full Text Available Background/Aim. Inflammation as a consequence of vascular injury after percutaneous coronary intervention (PCI is a pathological substrate of restenosis and of its complications. The aim of the study was to examine perprocedural inflammatory response expressed by soluble CD40 ligand (sCD40L and C-reactive protein (CRP in patients treated with PCI and dual antiplatelet therapy. Methods. The experimental group included 52 patients (80.8% men, age 60 ± 9 years with angina pectoris treated by PCI (22 urgent PCI with stent implantation, and dual antiplatelet therapy (tienopiridins and aspirin, according to the current recommendations for the execution of the intervention. The control group consisted of 8 patients (70.5% men, age 59 ± 7 years with angina pectoris, who had undergone coronarography taking aspirin 3 days prior to it. In all the patients 24 hours before and after the PCI concentrations of CRP and sCD40L in the blood were determined. Results. In the experimental group, the concentration of sCD40L was lower as compared to the control (p < 0.02. In 34 (65% patients postprocedural decrease in sCD40L was recorded, in 18 (34.6% of them increase, while in 50 (96% patients there was a rise in CRP. The patients with postprocedural fall in sCD40L hod greater preprocedural concentration of sCD40L (p < 0.001, and less postprocedural concentration of sCD40L (p < 0.001, compared to the group with an increase in sCD40L after the PCI, while CRP levels tients treated with emergency PCI compared to elective patietns had a postprocedural decrease in sCD40L (p = 0.02. Increase in the level of CRP was higher in the group with emergency PCI in relation to elective PCI (p < 0.01. Conclusion. Emergency PCI procedures in the treatment of patients with unstable angina pectoris lead to a postprocedural fall in the serum concentration of sCD40L. Dual antiplate therapy with tienopiridins and aspirin inhibits the release of sCD40L. Regardless a clinical presentation

  4. Feto-maternal outcomes of urgent open-heart surgery during pregnancy.

    Science.gov (United States)

    Hosseini, Saeid; Kashfi, Fahimeh; Samiei, Niloufar; Khamoushi, Amirjamshid; Ghavidel, Alireza Alizadeh; Yazdanian, Forouzan; Mirmesdagh, Yalda; Mestres, Carlos A

    2015-03-01

    Cardiac surgery during pregnancy is rarely required and potentially increases feto-maternal mortality. The study aim was to evaluate pregnancy outcomes in females who underwent open-heart surgery with cardiopulmonary bypass (CPB) during pregnancy. Between 1999 and 2014, a total of 16 pregnant women (mean age 27 ± 7 years; mean gestational age 13 ± 7.7 weeks) underwent urgent cardiac surgery using CPB. The preoperative diagnosis included prosthetic valve dysfunction in 12 women (five aortic, seven mitral), native valve endocarditis and critical aortic stenosis each in one woman, and intracardiac masses in two women. Eleven patients were in the first trimester, three in the second trimester, and two in the third trimester. A retrospective analysis was conducted that included maternal variables of age, gestational age, cardiac diagnosis, prior operations, surgical details, maternal morbidity and mortality and type of delivery, while fetal variables included incidence of low birth weight, prematurity, and fetal malformation. Patients were allocated to two groups: Group A (n = 9) included pregnant women with living neonates, while group B (n = 7) included pregnant women with an aborted fetus or dead neonate. All data were compared between the groups. There was no in-hospital maternal mortality. There were no significant differences between the two groups regarding age, gestational age, previous cardiac operation, type of surgery, duration of operation, perfusion pressure and core temperature during CPB. The CPB time was longer in group B (110.3 ± 57.1 min) than in group A (62 ± 15.7 min) (p = 0.028), as was the aortic cross-clamp time (54.3 ± 27.2 min and 38.7 ± 9.3 min in groups A and B, respectively) (p = 0.014). Group B patients received higher doses of inotropes perioperatively. No congenital abnormalities were identified in any of the living neonates. The durations of CPB and aortic cross-clamping may not affect maternal outcome, but shorter CPB and aortic

  5. Economic losses due to cystic echinococcosis in India: Need for urgent action to control the disease.

    Science.gov (United States)

    Singh, Balbir B; Dhand, Navneet K; Ghatak, Sandeep; Gill, Jatinder P S

    2014-01-01

    Cystic ehinococcosis (CE) caused by Echinococcus granulosus remains a neglected zoonotic disease despite its considerable human and animal health concerns. This is the first systematic analysis of the livestock and human related economic losses due to cystic echinococcosis in India. Data about human cases were obtained from a tertiary hospital. Human hydatidosis cases with and without surgical interventions were extrapolated to be 5647 and 17075 per year assuming a total human population of 1210193422 in India. Data about prevalence of hydatid cysts in important food producing animals were obtained from previously published abattoir based epidemiological surveys that reported a prevalence of 5.39% in cattle, 4.36% in buffaloes, 3.09% in pigs, 2.23% in sheep and 0.41% in goats. Animal population data were sourced from the latest census conducted by the Department of Animal Husbandry, Dairying and Fisheries, India. Other input parameters were obtained from published scientific literature. Probability distributions were included for many input values to account for variability and uncertainty. Sensitivity analyses were conducted to evaluate the effect of important parameters on the estimated economic losses. The analysis revealed a total annual median loss of Rs. 11.47 billion (approx. US $ 212.35 million). Cattle and buffalo industry accounted for most of the losses: 93.05% and 88.88% of the animal and total losses, respectively. Human hydatidosis related losses were estimated to be Rs. 472.72 million (approx. US $ 8.75 million) but are likely to be an under-estimate due to under-reporting of the disease in the country. The human losses more than quadrupled to Rs. 1953 million i.e. approx. US $ 36.17 million, when the prevalence of human undiagnosed cases was increased to 0.2% in the sensitivity analyses. The social loss and psychological distress were not taken into account for calculating human loss. The results highlight an urgent need for a science based policy

  6. Mid-IR super-continuum generation

    Science.gov (United States)

    Islam, Mohammed N.; Xia, Chenan; Freeman, Mike J.; Mauricio, Jeremiah; Zakel, Andy; Ke, Kevin; Xu, Zhao; Terry, Fred L., Jr.

    2009-02-01

    A Mid-InfraRed FIber Laser (MIRFIL) has been developed that generates super-continuum covering the spectral range from 0.8 to 4.5 microns with a time-averaged power as high as 10.5W. The MIRFIL is an all-fiber integrated laser with no moving parts and no mode-locked lasers that uses commercial off-the-shelf parts and leverages the mature telecom/fiber optics platform. The MIRFIL power can be easily scaled by changing the repetition rate and modifying the erbium-doped fiber amplifier. Some of the applications using the super-continuum laser will be described in defense, homeland security and healthcare. For example, the MIRFIL is being applied to a catheter-based medical diagnostic system to detect vulnerable plaque, which is responsible for most heart attacks resulting from hardening-of-the-arteries or atherosclerosis. More generally, the MIRFIL can be a platform for selective ablation of lipids without damaging normal protein or smooth muscle tissue.

  7. Review of Super Crunchers by Ian Ayers

    Directory of Open Access Journals (Sweden)

    Eric Gaze

    2009-07-01

    Full Text Available Ayers, I. Super Crunchers: Why Thinking-by-Numbers Is the New Way to be Smart. (Bantam Dell Publishing Group, 2007. 272 pp. Hard cover $25 ISBN 978-0-553-80540-6.Super Crunchers tells the story of how analyzing data is changing the ways in which decisions are made. We in the National Numeracy Network make a case for the importance of quantitative literacy by referring to how much quantitative information is now available to each of us: “a world awash in numbers.” Ian Ayres zeroes in on the people who are making a living crunching all of these data. From the seemingly innocuous (how wines are rated, and the scouting of baseball players to the life impacting (diagnosis of disease, and parole of inmates, this book paints a vivid portrayal of how data analysis is impacting decision making at every level in our society. The use of simple regression models and randomized trials is calling into question who the “experts” of the twenty-first century will be, and why thinking-by-numbers really is the new way to be smart.

  8. 3D super-virtual refraction interferometry

    KAUST Repository

    Lu, Kai

    2014-08-05

    Super-virtual refraction interferometry enhances the signal-to-noise ratio of far-offset refractions. However, when applied to 3D cases, traditional 2D SVI suffers because the stationary positions of the source-receiver pairs might be any place along the recording plane, not just along a receiver line. Moreover, the effect of enhancing the SNR can be limited because of the limitations in the number of survey lines, irregular line geometries, and azimuthal range of arrivals. We have developed a 3D SVI method to overcome these problems. By integrating along the source or receiver lines, the cross-correlation or the convolution result of a trace pair with the source or receiver at the stationary position can be calculated without the requirement of knowing the stationary locations. In addition, the amplitudes of the cross-correlation and convolution results are largely strengthened by integration, which is helpful to further enhance the SNR. In this paper, both synthetic and field data examples are presented, demonstrating that the super-virtual refractions generated by our method have accurate traveltimes and much improved SNR.

  9. Super Sensitive Mass Detection in Nonlinear Regime

    Science.gov (United States)

    Azizi, Saber; Ahmadian, Iman; Cetinkaya, Cetin; Rezazadeh, Ghader

    2015-11-01

    Nonlinear dynamics of a clamped-clamped micro-beam exposed to a two sided electrostatic actuation is investigated to determine super sensitive regions for mass detection. The objective is to investigate the sensitivity of the frequency spectrum of various regions in the phase space to the added mass and force the system to operate in its super sensitive regions by applying an appropriate pulse to its control electrodes. The electrostatic actuation in the top electrode is a combination of a DC, AC and a pulse voltage, the excitation on the lower electrode is only a DC and a pulse voltage. The governing equation of the motion, derived using the Hamiltonian principle, is discretized to an equivalent single-degree of freedom system using the Galerkin method. Depending on the applied electrostatic voltage to the micro-beam, it is demonstrated that the number and types of equilibrium points of the system can be modified. In this study, the level of the DC electrostatic voltage is chosen such a way that the system has three equilibrium points including two centers and a saddle node where the homoclinic orbit originates. According to the reported results, the mass sensing sensitivity depends on the operating orbit; some orbits exhibit considerably higher mass detection sensitivity to the added mass compared to that of a typical quartz crystal micro balance instrument.

  10. SuperAGILE data processing services

    CERN Document Server

    Lazzarotto, F; Del Monte, E; Donnarumma, I; Evangelista, Y; Feroci, M; Lapshov, I; Pacciani, L; Soffitta, P

    2009-01-01

    The SuperAGILE (SA) instrument is a X-ray detector for As- trophysics measurements, part of the Italian AGILE satellite for X-Ray and Gamma-Ray Astronomy launched at 23/04/2007 from India. SuperAGILE is now studying the sky in the 18 - 60 KeV energy band. It is detecting sources with advanced imaging and timing detection and good spectral detection capabilities. Several astrophysical sources has been detected and localized, including Crab, Vela and GX 301-2. The instrument has the skill to resolve correctly sources in a field of view of [-40, +40] degrees interval, with the angular resolution of 6 arcmin, and a spectral analysis with the resolution of 8 keV. Transient events are regularly detected by SA with the aid of its temporal resolution (2 microsec- onds) and using signal coincidence on different portions of the instrument, with confirmation from other observatories. The SA data processing scientic software performing at the AGILE Ground Segment is divided in modules, grouped in a processing pipeline na...

  11. Convolutional Neural Network Based dem Super Resolution

    Science.gov (United States)

    Chen, Zixuan; Wang, Xuewen; Xu, Zekai; Hou, Wenguang

    2016-06-01

    DEM super resolution is proposed in our previous publication to improve the resolution for a DEM on basis of some learning examples. Meanwhile, the nonlocal algorithm is introduced to deal with it and lots of experiments show that the strategy is feasible. In our publication, the learning examples are defined as the partial original DEM and their related high measurements due to this way can avoid the incompatibility between the data to be processed and the learning examples. To further extent the applications of this new strategy, the learning examples should be diverse and easy to obtain. Yet, it may cause the problem of incompatibility and unrobustness. To overcome it, we intend to investigate a convolutional neural network based method. The input of the convolutional neural network is a low resolution DEM and the output is expected to be its high resolution one. A three layers model will be adopted. The first layer is used to detect some features from the input, the second integrates the detected features to some compressed ones and the final step transforms the compressed features as a new DEM. According to this designed structure, some learning DEMs will be taken to train it. Specifically, the designed network will be optimized by minimizing the error of the output and its expected high resolution DEM. In practical applications, a testing DEM will be input to the convolutional neural network and a super resolution will be obtained. Many experiments show that the CNN based method can obtain better reconstructions than many classic interpolation methods.

  12. Polynomial super-gl(n) algebras

    CERN Document Server

    Jarvis, P D

    2003-01-01

    We introduce a class of finite dimensional nonlinear superalgebras $L = L_{\\bar{0}} + L_{\\bar{1}}$ providing gradings of $L_{\\bar{0}} = gl(n) \\simeq sl(n) + gl(1)$. Odd generators close by anticommutation on polynomials (of degree $>1$) in the $gl(n)$ generators. Specifically, we investigate `type I' super-$gl(n)$ algebras, having odd generators transforming in a single irreducible representation of $gl(n)$ together with its contragredient. Admissible structure constants are discussed in terms of available $gl(n)$ couplings, and various special cases and candidate superalgebras are identified and exemplified via concrete oscillator constructions. For the case of the $n$-dimensional defining representation, with odd generators $Q_{a}, \\bar{Q}{}^{b}$, and even generators ${E^{a}}_{b}$, $a,b = 1,...,n$, a three parameter family of quadratic super-$gl(n)$ algebras (deformations of $sl(n/1)$) is defined. In general, additional covariant Serre-type conditions are imposed, in order that the Jacobi identities be fulf...

  13. Hot Jupiters and Super-Earths

    CERN Document Server

    Mustill, Alexander James; Johansen, Anders

    2016-01-01

    We explore the role of dynamics in shaping planetary system multiplicities, focussing on two particular problems. (1) We propose that the lack of close-in super-Earths in hot Jupiter systems is a signature of the migration history of the hot Jupiters and helps to discriminate between different mechanisms of migration. We present N-body simulations of dynamical migration scenarios where proto-hot Jupiters are excited to high eccentricities prior to tidal circularisation and orbital decay. We show that in this scenario, the eccentric giant planet typically destroys planets in the inner system, in agreement with the observed lack of close super-Earth companions to hot Jupiters. (2) We explore the role of the dynamics of outer systems in affecting the multiplicities of close-in systems such as those discovered by Kepler. We consider specifically the effects of planet--planet scattering and Kozai perturbations on an exterior giant planet on the architecture of the inner system, and evaluate the ability of such sce...

  14. Aptamer Stainings for Super-resolution Microscopy.

    Science.gov (United States)

    de Castro, Maria Angela Gomes; Rammner, Burkhard; Opazo, Felipe

    2016-01-01

    Fluorescence microscopy is an invaluable tool to visualize molecules in their biological context with ease and flexibility. However, studies using conventional light microscopy have been limited to the resolution that light diffraction allows (i.e., ~200 nm). This limitation has been recently circumvented by several types of advanced fluorescence microscopy techniques, which have achieved resolutions of up to ~10 nm. The resulting enhanced imaging precision has helped to find important cellular details that were not visible using diffraction-limited instruments. However, it has also revealed that conventional stainings using large affinity tags, such as antibodies, are not accurate enough for these imaging techniques. Since aptamers are substantially smaller than antibodies, they could provide a real advantage in super-resolution imaging. Here we compare the live staining of transferrin receptors (TfnR) obtained with different fluorescently labeled affinity probes: aptamers, specific monoclonal antibodies, or the natural receptor ligand transferrin. We observed negligible differences between these staining strategies when imaging is performed with conventional light microscopy (i.e., laser scanning confocal microscopy). However, a clear superiority of the aptamer tag over antibodies became apparent in super-resolved images obtained with stimulated emission depletion (STED) microscopy.

  15. Sala polideportiva de Super-Lioran Francia

    Directory of Open Access Journals (Sweden)

    Mazzucconi, Vittorio

    1980-12-01

    Full Text Available The polysports hall of the Super-Lioran winter resort, located in a crater filled with aliuvionary deposits, consists of two clearly differentiated parts: a lower one, of concrete, where there is the skating rink and various services, and an upper one consisting of hyperbolic paraboloid elements. This roof is of adhered laminate wood. The laminate roof structure rests on the ground, and almost merges with it, to later emerge from the snow giving the assembly almost an abstract nature which helps to increase the beauty of the area.

    La sala polideportiva de la estación invernal de Super-Lioran, situada en un cráter relleno de depósitos aluvionares, consta de dos partes claramente diferenciadas: una inferior, de hormigón, donde se encuentran la pista de patinaje y los distintos servicios, y una superior formada por elementos de paraboloide hiperbólico. Esta cubierta es de madera laminada encolada. La estructura laminar de la cubierta se apoya en el suelo casi confundiéndose con él, y luego emerge desde la nieve proporcionando al conjunto un carácter casi abstracto que contribuye a aumentar la belleza de la zona.

  16. Nanostructured coatings for super hydrophobic textiles

    Indian Academy of Sciences (India)

    M Joshi; A Bhattacharyya; N Agarwal; S Parmar

    2012-11-01

    The promising aspects of nanocomposite coatings to mimic the nano roughened self cleaning surface of lotus leaf is explored in this paper. A detailed study on nanosilica and clay based nanocomposite coatings using dip coating and layer by layer self assembly (L–b–L) is being described where lotus leaf effect has been mimicked on the cotton fabric surface using these particles as they develop nanosized surface roughness which helps to produce a super-hydrophobic surface. Nanosilica performs better in creating nano roughness on cotton fabric wherein the contact angle is >150°. The water contact angle of 2 wt% fluoro emulsion (Nuva HPU) treated cotton fabric increases from 115° to 155° when the fabric is pretreated with 0.5 wt% nanosilica emulsion. The water repellency rating of fabric treated with 0.16 wt% nanosilica along with 2 wt% Nuva HPU is comparable to that of 4 wt% Nuva HPU treated cotton fabric. On the other hand, 40 bilayers of nanosilica need to be applied on cotton fabric surface through L–b–L technique to create uniform nano roughening and gives a water repellency rating of 4. The air permeability of L–b–L nanocoated cotton fabric is not adversely affected by the super-hydrophobic nanostructured coating.

  17. Stem Cell Transplants (For Parents)

    Science.gov (United States)

    ... Teaching Kids to Be Smart About Social Media Stem Cell Transplants KidsHealth > For Parents > Stem Cell Transplants Print A A A What's in this ... Recovery Coping en español Trasplantes de células madre Stem cells are cells in the body that have the ...

  18. Liver transplantation in the rat

    NARCIS (Netherlands)

    E.D. Wolff (Eric)

    1976-01-01

    textabstractDuring the past ten years progress in the field of vascular surgery and immunology has been such, that a steady improvement in the results of clinical organ transplantation can be observed. Also when a life threatening disease of the liver is present, liver transplantation may be conside

  19. Psychosocial Aspects of Heart Transplantation.

    Science.gov (United States)

    Suszycki, Lee H.

    1988-01-01

    Presents an overview of medical and psychosocial aspects of heart transplantation, with a focus on the program at Columbia-Presbyterian Medical Center. Describes social workers' interventions which help patients and families to achieve optimal psychosocial functioning before and after transplantation. (Author/ABL)

  20. Liver transplantation in the UK

    Institute of Scientific and Technical Information of China (English)

    SR Bramhall; E Minford; B Gunson; JAC Buckels

    2001-01-01

    Introduction: This paper provides a review of the practice of liver transplantation with the main emphasis on UK practice and indications for transplantation.``Referral and Assessment: This section reviews the process of referral and assessment of patients with liver disease with reference to UK practice.``Donor Organs: The practice of brainstem death and cadaveric organ donation is peculiar to individual countries and rates of donation and potential areas of improvement are addressed.``Operative Technique: The technical innovations that have led to liver transplantation becoming a semi-elective procedure are reviewed. Specific emphasis is made to the role of liver reduction and splitting and living related liver transplantation and how this impacts on UK practice are reviewed. The complications of liver transplantation are also reviewed with reference to our own unit.``Imrnunosuppression: The evolution of immunosuppression and its impact on liver transplantation are reviewed with some reference to future protocols.Retransplantation: The role of retransplantation is reviewed.``Outcome and Survival: The results of liver transplantation are reviewed with specific emphasis on our own experience.``Future: The future of liver transplantation is addressed.``