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Sample records for super elongation complex

  1. Transcriptional Elongation Control of Hepatitis B Virus Covalently Closed Circular DNA Transcription by Super Elongation Complex and BRD4.

    Science.gov (United States)

    Francisco, Joel Celio; Dai, Qian; Luo, Zhuojuan; Wang, Yan; Chong, Roxanne Hui-Heng; Tan, Yee Joo; Xie, Wei; Lee, Guan-Huei; Lin, Chengqi

    2017-10-01

    Chronic hepatitis B virus (HBV) infection can lead to liver cirrhosis and hepatocellular carcinoma. HBV reactivation during or after chemotherapy is a potentially fatal complication for cancer patients with chronic HBV infection. Transcription of HBV is a critical intermediate step of the HBV life cycle. However, factors controlling HBV transcription remain largely unknown. Here, we found that different P-TEFb complexes are involved in the transcription of the HBV viral genome. Both BRD4 and the super elongation complex (SEC) bind to the HBV genome. The treatment of bromodomain inhibitor JQ1 stimulates HBV transcription and increases the occupancy of BRD4 on the HBV genome, suggesting the bromodomain-independent recruitment of BRD4 to the HBV genome. JQ1 also leads to the increased binding of SEC to the HBV genome, and SEC is required for JQ1-induced HBV transcription. These findings reveal a novel mechanism by which the HBV genome hijacks the host P-TEFb-containing complexes to promote its own transcription. Our findings also point out an important clinical implication, that is, the potential risk of HBV reactivation during therapy with a BRD4 inhibitor, such as JQ1 or its analogues, which are a potential treatment for acute myeloid leukemia. Copyright © 2017 American Society for Microbiology.

  2. Reconstitution of Qbeta RNA replicase from a covalently bonded elongation factor Tu-Ts complex

    DEFF Research Database (Denmark)

    Brown, S; Blumenthal, T

    1976-01-01

    of these polypeptides, protein synthesis elongation factors EF-Tu and EF-Ts, can be covalently crosslinked with dimethyl suberimidate to form a complex which lacks the ability to catalyze the known host functions catalyzed by the individual elongation factors. Using a previously developed reconstitution system we have...... examined the effects of crosslinking the EF-Tu-Ts complex on reconstituted replicase activity. Renaturation is significantly more efficient when exogenously added native EF-Tu-Ts is crosslinked than when it is not. Crosslinked EF-Tu-Ts can be purified from a crude crosslinked postribosomal supernatant...... by its ability to replace EF-Tu and EF-Ts in the renaturation of denatured Qbeta replicase. A sample of Qbeta replicase with crosslinked EF-Tu-Ts replacing the individual elongation factors was prepared. Although it lacked EF-Tu and EF-Ts activities, it could initiate transcription of both poly...

  3. Elongation factor Ts directly facilitates the formation and disassembly of the Escherichia coli elongation factor Tu·GTP·aminoacyl-tRNA ternary complex.

    Science.gov (United States)

    Burnett, Benjamin J; Altman, Roger B; Ferrao, Ryan; Alejo, Jose L; Kaur, Navdep; Kanji, Joshua; Blanchard, Scott C

    2013-05-10

    Aminoacyl-tRNA (aa-tRNA) enters the ribosome in a ternary complex with the G-protein elongation factor Tu (EF-Tu) and GTP. EF-Tu·GTP·aa-tRNA ternary complex formation and decay rates are accelerated in the presence of the nucleotide exchange factor elongation factor Ts (EF-Ts). EF-Ts directly facilitates the formation and disassociation of ternary complex. This system demonstrates a novel function of EF-Ts. Aminoacyl-tRNA enters the translating ribosome in a ternary complex with elongation factor Tu (EF-Tu) and GTP. Here, we describe bulk steady state and pre-steady state fluorescence methods that enabled us to quantitatively explore the kinetic features of Escherichia coli ternary complex formation and decay. The data obtained suggest that both processes are controlled by a nucleotide-dependent, rate-determining conformational change in EF-Tu. Unexpectedly, we found that this conformational change is accelerated by elongation factor Ts (EF-Ts), the guanosine nucleotide exchange factor for EF-Tu. Notably, EF-Ts attenuates the affinity of EF-Tu for GTP and destabilizes ternary complex in the presence of non-hydrolyzable GTP analogs. These results suggest that EF-Ts serves an unanticipated role in the cell of actively regulating the abundance and stability of ternary complex in a manner that contributes to rapid and faithful protein synthesis.

  4. The role of Glu259 in Escherichia coli elongation factor Tu in ternary complex formation

    DEFF Research Database (Denmark)

    Nautrup Pedersen, Gitte; Rattenborg, Thomas; Knudsen, Charlotte Rohde

    1998-01-01

    Determination of the crystal structure of the ternary complex formed between elongation factor Tu:GTP and aminoacylated tRNA revealed three regions of interaction between elongation factor Tu and tRNA. The structure indicates that the conserved glutamic acid at position 271 in Thermus aquaticus EF-Tu...... could be involved in the binding of the 3' CCA-Phe end of the aminoacylated tRNA. Therefore, the corresponding residue, Glu259, of Escherichia coli EF-Tu was mutated into alanine, aspartic acid, glutamine and tyrosine, in order to substantiate the crystallographic structural evidence and to obtain...... of interaction with tRNA, while mutation to tyrosine abolished completely the interaction with tRNA. Finally, mutation to glutamine resulted in an elongation factor Tu variant behaving like the wild type. In conclusion, the environment around the site binding the CCA-Phe end of the tRNA is very restricted...

  5. The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.

    Directory of Open Access Journals (Sweden)

    Jachen A Solinger

    2010-01-01

    Full Text Available Although acetylated alpha-tubulin is known to be a marker of stable microtubules in neurons, precise factors that regulate alpha-tubulin acetylation are, to date, largely unknown. Therefore, a genetic screen was employed in the nematode Caenorhabditis elegans that identified the Elongator complex as a possible regulator of alpha-tubulin acetylation. Detailed characterization of mutant animals revealed that the acetyltransferase activity of the Elongator is indeed required for correct acetylation of microtubules and for neuronal development. Moreover, the velocity of vesicles on microtubules was affected by mutations in Elongator. Elongator mutants also displayed defects in neurotransmitter levels. Furthermore, acetylation of alpha-tubulin was shown to act as a novel signal for the fine-tuning of microtubules dynamics by modulating alpha-tubulin turnover, which in turn affected neuronal shape. Given that mutations in the acetyltransferase subunit of the Elongator (Elp3 and in a scaffold subunit (Elp1 have previously been linked to human neurodegenerative diseases, namely Amyotrophic Lateral Sclerosis and Familial Dysautonomia respectively highlights the importance of this work and offers new insights to understand their etiology.

  6. Translational Capacity of a Cell Is Determined during Transcription Elongation via the Ccr4-Not Complex

    Directory of Open Access Journals (Sweden)

    Ishaan Gupta

    2016-05-01

    Full Text Available The current understanding of gene expression considers transcription and translation to be independent processes. Challenging this notion, we found that translation efficiency is determined during transcription elongation through the imprinting of mRNAs with Not1, the central scaffold of the Ccr4-Not complex. We determined that another subunit of the complex, Not5, defines Not1 binding to specific mRNAs, particularly those produced from ribosomal protein genes. This imprinting mechanism specifically regulates ribosomal protein gene expression, which in turn determines the translational capacity of cells. We validate our model by SILAC and polysome profiling experiments. As a proof of concept, we demonstrate that enhanced translation compensates for transcriptional elongation stress. Taken together, our data indicate that in addition to defining mRNA stability, components of the Ccr4-Not imprinting complex regulate RNA translatability, thus ensuring global gene expression homeostasis.

  7. Elongation Factor Ts Directly Facilitates the Formation and Disassembly of the Escherichia coli Elongation Factor Tu·GTP·Aminoacyl-tRNA Ternary Complex*

    Science.gov (United States)

    Burnett, Benjamin J.; Altman, Roger B.; Ferrao, Ryan; Alejo, Jose L.; Kaur, Navdep; Kanji, Joshua; Blanchard, Scott C.

    2013-01-01

    Aminoacyl-tRNA enters the translating ribosome in a ternary complex with elongation factor Tu (EF-Tu) and GTP. Here, we describe bulk steady state and pre-steady state fluorescence methods that enabled us to quantitatively explore the kinetic features of Escherichia coli ternary complex formation and decay. The data obtained suggest that both processes are controlled by a nucleotide-dependent, rate-determining conformational change in EF-Tu. Unexpectedly, we found that this conformational change is accelerated by elongation factor Ts (EF-Ts), the guanosine nucleotide exchange factor for EF-Tu. Notably, EF-Ts attenuates the affinity of EF-Tu for GTP and destabilizes ternary complex in the presence of non-hydrolyzable GTP analogs. These results suggest that EF-Ts serves an unanticipated role in the cell of actively regulating the abundance and stability of ternary complex in a manner that contributes to rapid and faithful protein synthesis. PMID:23539628

  8. Elongator complex is required for long-term olfactory memory formation in Drosophila.

    Science.gov (United States)

    Yu, Dinghui; Tan, Ying; Chakraborty, Molee; Tomchik, Seth; Davis, Ronald L

    2018-04-01

    The evolutionarily conserved Elongator Complex associates with RNA polymerase II for transcriptional elongation. Elp3 is the catalytic subunit, contains histone acetyltransferase activity, and is associated with neurodegeneration in humans. Elp1 is a scaffolding subunit and when mutated causes familial dysautonomia. Here, we show that elp3 and elp1 are required for aversive long-term olfactory memory in Drosophila RNAi knockdown of elp3 in adult mushroom bodies impairs long-term memory (LTM) without affecting earlier forms of memory. RNAi knockdown with coexpression of elp3 cDNA reverses the impairment. Similarly, RNAi knockdown of elp1 impairs LTM and coexpression of elp1 cDNA reverses this phenotype. The LTM deficit in elp3 and elp1 knockdown flies is accompanied by the abolishment of a LTM trace, which is registered as increased calcium influx in response to the CS+ odor in the α-branch of mushroom body neurons. Coexpression of elp1 or elp3 cDNA rescues the memory trace in parallel with LTM. These data show that the Elongator complex is required in adult mushroom body neurons for long-term behavioral memory and the associated long-term memory trace. © 2018 Yu et al.; Published by Cold Spring Harbor Laboratory Press.

  9. The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution.

    OpenAIRE

    Czworkowski, J; Wang, J; Steitz, T A; Moore, P B

    1994-01-01

    Elongation factor G (EF-G) catalyzes the translocation step of protein synthesis in bacteria, and like the other bacterial elongation factor, EF-Tu--whose structure is already known--it is a member of the GTPase superfamily. We have determined the crystal structure of EF-G--GDP from Thermus thermophilus. It is an elongated molecule whose large, N-terminal domain resembles the G domain of EF-Tu, except for a 90 residue insert, which covers a surface that is involved in nucleotide exchange in E...

  10. Ranking stability and super-stable nodes in complex networks.

    Science.gov (United States)

    Ghoshal, Gourab; Barabási, Albert-László

    2011-07-19

    Pagerank, a network-based diffusion algorithm, has emerged as the leading method to rank web content, ecological species and even scientists. Despite its wide use, it remains unknown how the structure of the network on which it operates affects its performance. Here we show that for random networks the ranking provided by pagerank is sensitive to perturbations in the network topology, making it unreliable for incomplete or noisy systems. In contrast, in scale-free networks we predict analytically the emergence of super-stable nodes whose ranking is exceptionally stable to perturbations. We calculate the dependence of the number of super-stable nodes on network characteristics and demonstrate their presence in real networks, in agreement with the analytical predictions. These results not only deepen our understanding of the interplay between network topology and dynamical processes but also have implications in all areas where ranking has a role, from science to marketing.

  11. The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression.

    Science.gov (United States)

    Egloff, Sylvain; Vitali, Patrice; Tellier, Michael; Raffel, Raoul; Murphy, Shona; Kiss, Tamás

    2017-04-03

    The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates the mRNA elongation capacity of RNA polymerase II (RNAPII) through controlling the nuclear activity of positive transcription elongation factor b (P-TEFb). Here, we demonstrate that the human 7SK snRNP also functions as a canonical transcription factor that, in collaboration with the little elongation complex (LEC) comprising ELL, Ice1, Ice2, and ZC3H8, promotes transcription of RNAPII-specific spliceosomal snRNA and small nucleolar RNA (snoRNA) genes. The 7SK snRNA specifically associates with a fraction of RNAPII hyperphosphorylated at Ser5 and Ser7, which is a hallmark of RNAPII engaged in snRNA synthesis. Chromatin immunoprecipitation (ChIP) and chromatin isolation by RNA purification (ChIRP) experiments revealed enrichments for all components of the 7SK snRNP on RNAPII-specific sn/snoRNA genes. Depletion of 7SK snRNA or Larp7 disrupts LEC integrity, inhibits RNAPII recruitment to RNAPII-specific sn/snoRNA genes, and reduces nascent snRNA and snoRNA synthesis. Thus, through controlling both mRNA elongation and sn/snoRNA synthesis, the 7SK snRNP is a key regulator of nuclear RNA production by RNAPII. © 2017 The Authors.

  12. Peroxisome proliferator-activated receptor gamma recruits the positive transcription elongation factor b complex to activate transcription and promote adipogenesis

    DEFF Research Database (Denmark)

    Iankova, Irena; Petersen, Rasmus K; Annicotte, Jean-Sébastien

    2006-01-01

    Positive transcription elongation factor b (P-TEFb) phosphorylates the C-terminal domain of RNA polymerase II, facilitating transcriptional elongation. In addition to its participation in general transcription, P-TEFb is recruited to specific promoters by some transcription factors such as c......-Myc or MyoD. The P-TEFb complex is composed of a cyclin-dependent kinase (cdk9) subunit and a regulatory partner (cyclin T1, cyclin T2, or cyclin K). Because cdk9 has been shown to participate in differentiation processes, such as muscle cell differentiation, we studied a possible role of cdk9...... with and phosphorylation of peroxisome proliferator-activated receptor gamma (PPARgamma), which is the master regulator of this process, on the promoter of PPARgamma target genes. PPARgamma-cdk9 interaction results in increased transcriptional activity of PPARgamma and therefore increased adipogenesis....

  13. The formation of super-dislocation/micropipe complexes in 6H-SiC

    Energy Technology Data Exchange (ETDEWEB)

    Giocondi, J.; Rohrer, G.S.; Skowronski, M. [Carnegie Mellon Univ., Pittsburgh, PA (United States). Dept. of Materials Science and Engineering; Balakrishna, V.; Augustine, G.; Hobgood, H.McD.; Hopkins, R.H. [Northrop Grumman Science and Technology Center, Pittsburgh PA (United States)

    1998-06-01

    Atomic force microscope images of surface/micropipe intersections on the (0001) growth surface of a 6H-SiC single crystal grown by the physical vapor transport method indicate that micropipes are associated with super-dislocations and that micron-scale deposits of a heterogeneous phase are frequently found in the vicinity of the defect. Based on our observations, we propose a model for the formation of super-dislocation/micropipe complexes that involves the coalescence of unit screw dislocations. The unit dislocations are forced together as large steps grow around heterogeneous material on the surface. (orig.) 5 refs.

  14. Effector region of the translation elongation factor EF-Tu.GTP complex stabilizes an orthoester acid intermediate structure of aminoacyl-tRNA in a ternary complex.

    Science.gov (United States)

    Förster, C; Limmer, S; Zeidler, W; Sprinzl, M

    1994-01-01

    tRNA(Val) from Escherichia coli was aminoacylated with [1-13C]valine and its complex with Thermus thermophilus elongation factor EF-Tu.GTP was analyzed by 13C NMR spectroscopy. The results suggest that the aminoacyl residue of the valyl-tRNA in ternary complex with bacterial EF-Tu and GTP is not attached to tRNA by a regular ester bond to either a 2'- or 3'-hydroxyl group; instead, an intermediate orthoester acid structure with covalent linkage to both vicinal hydroxyls of the terminal adenosine-76 is formed. Mutation of arginine-59 located in the effector region of EF-Tu, a conserved residue in protein elongation factors and the alpha subunits of heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins), abolishes the stabilization of the orthoester acid structure of aminoacyl-tRNA. PMID:8183898

  15. Interaction of a Ni(II) tetraazaannulene complex with elongated fullerenes as simple models for carbon nanotubes.

    Science.gov (United States)

    Henao-Holguín, Laura Verónica; Basiuk, Vladimir A

    2015-06-01

    Nickel(II) complex of 5,14-dihydro-6,8,15,17-tetramethyldibenzo[b,i][1,4,8,11] tetraazacyclotetradecine (NiTMTAA), which can be employed for noncovalent functionalization of carbon nanotubes (CNTs), represents a more complex and interesting case in terms of structure of the resulting nanohybrids, as compared to the related materials functionalized with porphyrins and phthalocyanines. Due to its saddle shape, the NiTMTAA molecule adsorbed can adopt different, energetically non-equivalent orientations with respect to CNT, depending on whether CH3 or C6H4 groups contact the latter. The main goal of the present work was to provide information on the interactions of NiTMTAA with simple single-walled CNT (SWNT) models accessible for dispersion-corrected DFT calculations. For reasons of comparison, we employed three such functionals: M06-2X and LC-BLYP as implemented in Gaussian 09 package, and PBE-G as implemented in Materials Studio 6.0. In order to roughly estimate the effect of nanotube chirality on the interaction strenght, we considered two short closed-end SWNT models (also referred to as 'elongated fullerenes'), one armchair and one zigzag, derived from C60 and C80 hemispheres. In addition, we calculated similar complexes with C60, as well as I h and D 5h isomers of C80. The results were analyzed in terms of optimized geometries, formation energies, HOMO-LUMO gap energies, and intermolecular separations. Graphical Abstract Interaction of Ni(II) tetraazaannulene complex with elongated fullerenes.

  16. Isolation of amino acid activating subunit-pantetheine protein complexes: Their role in chain elongation in tyrocidine synthesis

    Science.gov (United States)

    Lee, Sung G.; Lipmann, Fritz

    1977-01-01

    Dissociation of the multienzymes of tyrocidine synthesis by prolonged incubation of crude extracts of Bacillus brevis (Dubos strain, ATCC 8185) has yielded, on Sephadex G-100 chromatography, two fractions of amino acid activating subunits, a larger one of 70,000 daltons and a smaller one of 90,000 daltons; the latter was a complex consisting of the 70,000 dalton subunit and the pantetheine-carrying protein of about 20,000 daltons. When it dissociated, the intermediate enzyme, which activates three amino acids, contained two-thirds of the subunits in the 70,000 dalton and one-third in the 90,000 dalton fraction; the heavy enzyme, which activates six amino acids, contained five-sixths of the subunits in the former fraction and one-sixth in the latter. Both fractions showed ATP-PPi exchange with all amino acids that are activated by the respective polyenzymes. With proline as an example, the 70,000 dalton subunit exhibited a single low-affinity binding site, which should correspond to the peripheral thiol acceptor site, whereas the 90,000 dalton subunit showed both a low-affinity binding site and an additional high-affinity site for proline; the high-affinity site is attributed to the pantetheine present on the pantetheine-carrying protein, and suggests that amino acids are translocated from the peripheral SH to the pantetheine-carrying moiety during chain elongation. This was confirmed by the observation that the 90,000 dalton complex, when incubated with the light enzyme in the presence of phenylalanine and proline, produced DPhe-Pro dipeptide that cyclized into DPhe-Pro diketopiperazine, but the 70,000 dalton activating subunit, when similarly incubated, did not. After subunit dissociation, however, no further elongation occurred after the transfer from phenylalanine to proline. Images PMID:196286

  17. Mapping the human translation elongation factor eEF1H complex using the yeast two-hybrid system

    DEFF Research Database (Denmark)

    Mansilla, Francisco; Friis, Irene; Jadidi, Mandana

    2002-01-01

    In eukaryotes, the eukaryotic translation elongation factor eEF1A responsible for transporting amino-acylated tRNA to the ribosome forms a higher-order complex, eEF1H, with its guanine-nucleotide-exchange factor eEF1B. In metazoans, eEF1B consists of three subunits: eEF1B alpha, eEF1B eta and eEF1B...... of in vitro experiments have been proposed for the macromolecular organization of the eEF1H complex. However, these models differ in various aspects. This might be due to the difficulties of handling, particularly the eEF1B beta and eEF1B gamma subunits in vitro. Here, the human eEF1H complex is for the first...... gamma:eEF1B beta, where the last was observed using a three-hybrid approach. Surprisingly, eEF1A2 showed no or only little affinity for the guanine-nucleotide-exchange factors. Truncated versions of the subunits of eEF1B were used to orientate these subunits within the resulting model. The model unit...

  18. Direct extraction of uranium and plutonium from oxide fuel using TBP-HNO3 complex for super-DIREX process

    International Nuclear Information System (INIS)

    Miura, S.; Kamiya, M.; Nomura, K.; Koyama, T.; Ogum, S.; Shimada, T.; Mori, Y.; Enokida, Y.

    2004-01-01

    Super-DIREX is a new reprocessing method which has high economical efficiency. Experimental study of this process was started on the direct extraction of U and Pu from irradiated MOX fuel by the supercritical carbon dioxide (SFCO 2 ) containing TBP-HNO 3 complex. This report describes direct extraction of U and Pu with TBP-HNO 3 complex at atmospheric pressure, as the first test for irradiated fuel, in order to investigate the applicability of SFCO 2 containing TBP-HNO 3 complex. In this test, dependency on dissolution temperature, Pu content, fuel/ TBP-HNO 3 complex ratio and effect of voloxidation were investigated. From these results, TBP-HNO 3 complex was found to be effective in the respect of the recovery of U and Pu. The number of the process step in dissolution and co-extraction is small, and amount of waste can be reduced. It is applicable to the direct extraction in Super-DIREX. (authors)

  19. Super-resolution mapping of scaffold nucleoporins in the nuclear pore complex.

    Science.gov (United States)

    Ma, Jiong; Kelich, Joseph M; Junod, Samuel L; Yang, Weidong

    2017-04-01

    The nuclear pore complex (NPC), composed of ∼30 different nucleoporins (Nups), is one of the largest supramolecular structures in eukaryotic cells. Its octagonal ring scaffold perforates the nuclear envelope and features a unique molecular machinery that regulates nucleocytoplasmic transport. However, the precise copy number and the spatial location of each Nup in the native NPC remain obscure due to the inherent difficulty of counting and localizing proteins inside of the sub-micrometer supramolecular complex. Here, we combined super-resolution single-point edge-excitation subdiffraction (SPEED) microscopy and nanobody-specific labeling to reveal the spatial distribution of scaffold Nups within three separate layers in the native NPC with a precision of ∼3 nm. Our data reveal both the radial and axial spatial distributions for Pom121, Nup37 and Nup35 and provide evidence for their copy numbers of 8, 32 and 16, respectively, per NPC. This approach can help pave the path for mapping the entirety of Nups in native NPCs and also other structural components of macromolecular complexes. © 2017. Published by The Company of Biologists Ltd.

  20. Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5.

    Science.gov (United States)

    Blythe, Amanda; Gunasekara, Sanjika; Walshe, James; Mackay, Joel P; Hartzog, Grant A; Vrielink, Alice

    2014-08-01

    Spt4/5 is a hetero-dimeric transcription elongation factor that can both inhibit and promote transcription elongation by RNA polymerase II (RNAPII). However, Spt4/5's mechanism of action remains elusive. Spt5 is an essential protein and the only universally-conserved RNAP-associated transcription elongation factor. The protein contains multiple Kyrpides, Ouzounis and Woese (KOW) domains. These domains, in other proteins, are thought to bind RNA although there is little direct evidence in the literature to support such a function in Spt5. This could be due, at least in part, to difficulties in expressing and purifying recombinant Spt5. When expressed in Escherichia coli (E. coli), Spt5 is innately insoluble. Here we report a new approach for the successful expression and purification of milligram quantities of three different multi-KOW domain complexes of Saccharomyces cerevisiae Spt4/5 for use in future functional studies. Using the E. coli strain Rosetta2 (DE3) we have developed strategies for co-expression of Spt4 and multi-KOW domain Spt5 complexes from the bi-cistronic pET-Duet vector. In a second strategy, Spt4/5 was expressed via co-transformation of Spt4 in the vector pET-M11 with Spt5 ubiquitin fusion constructs in the vector pHUE. We characterized the multi-KOW domain Spt4/5 complexes by Western blot, limited proteolysis, circular dichroism, SDS-PAGE and size exclusion chromatography-multiangle light scattering and found that the proteins are folded with a Spt4:Spt5 hetero-dimeric stoichiometry of 1:1. These expression constructs encompass a larger region of Spt5 than has previously been reported, and will provide the opportunity to elucidate the biological function of the multi-KOW containing Spt5. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Usage of super high speed computer for clarification of complex phenomena

    International Nuclear Information System (INIS)

    Sekiguchi, Tomotsugu; Sato, Mitsuhisa; Nakata, Hideki; Tatebe, Osami; Takagi, Hiromitsu

    1999-01-01

    This study aims at construction of an efficient super high speed computer system application environment in response to parallel distributed system with easy transplantation to different computer system and different number by conducting research and development on super high speed computer application technology required for elucidation of complicated phenomenon in elucidation of complicated phenomenon of nuclear power field due to computed scientific method. In order to realize such environment, the Electrotechnical Laboratory has conducted development on Ninf, a network numerical information library. This Ninf system can supply a global network infrastructure for worldwide computing with high performance on further wide range distributed network (G.K.)

  2. Crystallization and preliminary X-ray analysis of the mRNA-binding domain of elongation factor SelB from Escherichia coli in complex with RNA

    International Nuclear Information System (INIS)

    Soler, Nicolas; Fourmy, Dominique; Yoshizawa, Satoko

    2007-01-01

    The mRNA-binding domain of E. coli selenocysteine-specific elongation factor SelB (residues 478–614; SelB-WH3/4) was overproduced in E. coli and its cognate mRNA ligand, 23 nucleotides of the SECIS RNA hairpin, was prepared by in vitro transcription. The purified SelB-WH3/4–SECIS RNA complex crystallized in space group C2 and diffracted to 2.3 Å. In bacteria, selenocysteine (the 21st amino acid) is incorporated into proteins via machinery that includes SelB, a specific translational elongation factor. SelB binds to an mRNA hairpin called the selenocysteine-insertion sequence (SECIS) and delivers selenocysteyl-tRNA Sec to the ribosomal A site. The minimum C-terminal fragment (residues 478–614) of Escherichia coli SelB (SelB-WH3/4) required for SECIS binding has been overexpressed and purified. This protein was crystallized in complex with 23 nucleotides of the SECIS hairpin at 294 K using the hanging-drop vapour-diffusion method. A data set was collected to 2.3 Å resolution from a single crystal at 100 K using ESRF beamline BM-30. The crystal belongs to space group C2, with unit-cell parameters a = 103.50, b = 56.51, c = 48.41 Å. The asymmetric unit contains one WH3/4-domain–RNA complex. The Matthews coefficient was calculated to be 3.37 Å 3 Da −1 and the solvent content was estimated to be 67.4%

  3. Poly(vinyl alcohol) composite films with high percent elongation prepared from amylose-fatty ammonium salt inclusion complexes

    Science.gov (United States)

    Amylose inclusion complexes prepared from cationic fatty ammonium salts and jet-cooked high amylose starch were combined with poly(vinyl alcohol) (PVOH) to form glycerol-plasticized films. Their tensile properties were compared with similar films prepared previously with analogous anionic fatty acid...

  4. Small-angle X-ray Solution Scattering Study of the Multi-aminoacyl-tRNA Synthetase Complex Reveals an Elongated and Multi-armed particle*

    Science.gov (United States)

    Dias, José; Renault, Louis; Pérez, Javier; Mirande, Marc

    2013-01-01

    In animal cells, nine aminoacyl-tRNA synthetases are associated with the three auxiliary proteins p18, p38, and p43 to form a stable and conserved large multi-aminoacyl-tRNA synthetase complex (MARS), whose molecular mass has been proposed to be between 1.0 and 1.5 MDa. The complex acts as a molecular hub for coordinating protein synthesis and diverse regulatory signal pathways. Electron microscopy studies defined its low resolution molecular envelope as an overall rather compact, asymmetric triangular shape. Here, we have analyzed the composition and homogeneity of the native mammalian MARS isolated from rabbit liver and characterized its overall internal structure, size, and shape at low resolution by hydrodynamic methods and small-angle x-ray scattering in solution. Our data reveal that the MARS exhibits a much more elongated and multi-armed shape than expected from previous reports. The hydrodynamic and structural features of the MARS are large compared with other supramolecular assemblies involved in translation, including ribosome. The large dimensions and non-compact structural organization of MARS favor a large protein surface accessibility for all its components. This may be essential to allow structural rearrangements between the catalytic and cis-acting tRNA binding domains of the synthetases required for binding the bulky tRNA substrates. This non-compact architecture may also contribute to the spatiotemporal controlled release of some of its components, which participate in non-canonical functions after dissociation from the complex. PMID:23836901

  5. An elongated model of the Xenopus laevis transcription factor IIIA-5S ribosomal RNA complex derived from neutron scattering and hydrodynamic measurements

    International Nuclear Information System (INIS)

    Timmins, P.A.; Langowski, J.; Brown, R.S.

    1988-01-01

    The precise molecular composition of the Xenopus laevis TFIIIA-5S ribosomal RNA complex (7S particle) has been established from small angle neutron and dynamic light scattering. The molecular weight of the particle was found to be 95,700±10,000 and 86,700±9,000 daltons from these two methods respectively. The observed match point of 54.4% D 2 O obtained from contrast variation experiments indicates a 1:1 molar ratio. It is concluded that only a single molecule of TFIIIA, a zinc-finger protein, and of 5S RNA are present in this complex. A simple elongated cylindrical model with dimensions of 140 angstrom length and 59 angstrom diameter is compatible with the neutron results. A globular model can be excluded by the shallow nature of the neutron scattering curves. It is proposed that the observed difference of 15 angstrom in length between the 7S particle and isolated 5S RNA most likely indicates that part(s) of the protein protrudes from the end(s) of the RNA molecule. There is no biochemical evidence for any gross alteration in 5S RNA conformation upon binding to TFIIIA

  6. [Cyto-embryologic investigation of super dwarf wheat grown on board of the Mir orbital complex

    Science.gov (United States)

    Veselova, T. D.; Il'ina, G. M.; Dzhaliova, Kh Kh; Levinskikh, M. A.; Sychev, V. N.; Salisbury, F. B.; Campbell, W. F.

    1999-01-01

    The cytoembryologic analysis of wet and dry samples of super dwarf wheat cultivated in greenhouse SVET aboard the MIR station over the whole cycle of vegetation was made with the use of light microscopy. Characteristic features of wheat development in space flight are plentiful early tillering, and formation and rapid growth of side shoots. Elementary spikelets in the composite head were more numerous but the top spikelets were rudimentary and, therefore, the ripe head contained less of these spikelets as compared with the ground controls (9-13 and 14, respectively). The number of florets in a spike was also higher reaching 14-16 vs. 7-8 in the control. Typically, no more than 4 to 5 florets vs. 3 in the control were fully differentiated while the others died off earlier in development. The fact that there were no caryopses found in the flight crop is explained by absolute male sterility appearing at different stages of staminal development: before archesporium formation, on the stage of differentiated archesporium, during meiosis, on the stage of microspores or uninucleate "pollen". The female generative system developed mainly without abnormalities. An assumption was made that elevated ethylene concentrations in the MIR atmosphere at the time of the wheat experiment were the cause for abnormal development of the male generative system which led to barrenness of the super dwarf wheat crop.

  7. Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO.

    Directory of Open Access Journals (Sweden)

    Marcos Rodrigo Alborghetti

    Full Text Available Cytoskeleton and protein trafficking processes, including vesicle transport to synapses, are key processes in neuronal differentiation and axon outgrowth. The human protein FEZ1 (fasciculation and elongation protein zeta 1 / UNC-76, in C. elegans, SCOCO (short coiled-coil protein / UNC-69 and kinesins (e.g. kinesin heavy chain / UNC116 are involved in these processes. Exploiting the feature of FEZ1 protein as a bivalent adapter of transport mediated by kinesins and FEZ1 protein interaction with SCOCO (proteins involved in the same path of axonal growth, we investigated the structural aspects of intermolecular interactions involved in this complex formation by NMR (Nuclear Magnetic Resonance, cross-linking coupled with mass spectrometry (MS, SAXS (Small Angle X-ray Scattering and molecular modelling. The topology of homodimerization was accessed through NMR (Nuclear Magnetic Resonance studies of the region involved in this process, corresponding to FEZ1 (92-194. Through studies involving the protein in its monomeric configuration (reduced and dimeric state, we propose that homodimerization occurs with FEZ1 chains oriented in an anti-parallel topology. We demonstrate that the interaction interface of FEZ1 and SCOCO defined by MS and computational modelling is in accordance with that previously demonstrated for UNC-76 and UNC-69. SAXS and literature data support a heterotetrameric complex model. These data provide details about the interaction interfaces probably involved in the transport machinery assembly and open perspectives to understand and interfere in this assembly and its involvement in neuronal differentiation and axon outgrowth.

  8. Super Riemann surfaces

    International Nuclear Information System (INIS)

    Rogers, Alice

    1990-01-01

    A super Riemann surface is a particular kind of (1,1)-dimensional complex analytic supermanifold. From the point of view of super-manifold theory, super Riemann surfaces are interesting because they furnish the simplest examples of what have become known as non-split supermanifolds, that is, supermanifolds where the odd and even parts are genuinely intertwined, as opposed to split supermanifolds which are essentially the exterior bundles of a vector bundle over a conventional manifold. However undoubtedly the main motivation for the study of super Riemann surfaces has been their relevance to the Polyakov quantisation of the spinning string. Some of the papers on super Riemann surfaces are reviewed. Although recent work has shown all super Riemann surfaces are algebraic, some areas of difficulty remain. (author)

  9. Succinate dehydrogenase assembly factor 2 is needed for assembly and activity of mitochondrial complex II and for normal root elongation in Arabidopsis.

    Science.gov (United States)

    Huang, Shaobai; Taylor, Nicolas L; Ströher, Elke; Fenske, Ricarda; Millar, A Harvey

    2013-02-01

    Mitochondria complex II (succinate dehydrogenase, SDH) plays a central role in respiratory metabolism as a component of both the electron transport chain and the tricarboxylic acid cycle. We report the identification of an SDH assembly factor by analysis of T-DNA insertions in At5g51040, a protein with unknown function that was identified by mass spectrometry analysis as a low abundance mitochondrial protein. This gene is co-expressed with a number of genes encoding mitochondrial proteins, including SDH1-1, and has low partial sequence similarity to human SDHAF2, a protein required for flavin-adenine dinucleotide (FAD) insertion into SDH. In contrast to observations of other SDH deficient lines in Arabidopsis, the sdhaf2 line did not affect photosynthetic rate or stomatal conductance, but instead showed inhibition of primary root elongation with early lateral root emergence, presumably due to the low SDH activity caused by the reduced abundance of SDHAF2. Both roots and leaves showed succinate accumulation but different responses in the abundance of other organic acids and amino acids assayed. Isolated mitochondria showed lowered SDH1 protein abundance, lowered maximal SDH activity and less protein-bound flavin-adenine dinucleotide (FAD) at the molecular mass of SDH1 in the gel separation. The short root phenotype and SDH function of sdhaf2 was fully complemented by transformation with SDHAF2. Application of the SDH inhibitor, malonate, phenocopied the sdhaf2 root architecture in WT. Whole root respiratory assays showed no difference between WT and sdhaf2, but micro-respirometry of the tips of roots clearly showed low oxygen consumption in sdhaf2 which could explain a metabolic deficit responsible for root tip growth. © 2012 The Authors The Plant Journal © 2012 Blackwell Publishing Ltd.

  10. Isolation and characterization of PSI-LHCI super-complex and their sub-complexes from a red alga Cyanidioschyzon merolae.

    Science.gov (United States)

    Tian, Lirong; Liu, Zheyi; Wang, Fangjun; Shen, Liangliang; Chen, Jinghua; Chang, Lijing; Zhao, Songhao; Han, Guangye; Wang, Wenda; Kuang, Tingyun; Qin, Xiaochun; Shen, Jian-Ren

    2017-09-01

    Photosystem I (PSI)-light-harvesting complex I (LHCI) super-complex and its sub-complexes PSI core and LHCI, were purified from a unicellular red alga Cyanidioschyzon merolae and characterized. PSI-LHCI of C. merolae existed as a monomer with a molecular mass of 580 kDa. Mass spectrometry analysis identified 11 subunits (PsaA, B, C, D, E, F, I, J, K, L, O) in the core complex and three LHCI subunits, CMQ142C, CMN234C, and CMN235C in LHCI, indicating that at least three Lhcr subunits associate with the red algal PSI core. PsaG was not found in the red algae PSI-LHCI, and we suggest that the position corresponding to Lhca1 in higher plant PSI-LHCI is empty in the red algal PSI-LHCI. The PSI-LHCI complex was separated into two bands on native PAGE, suggesting that two different complexes may be present with slightly different protein compositions probably with respective to the numbers of Lhcr subunits. Based on the results obtained, a structural model was proposed for the red algal PSI-LHCI. Furthermore, pigment analysis revealed that the C. merolae PSI-LHCI contained a large amount of zeaxanthin, which is mainly associated with the LHCI complex whereas little zeaxanthin was found in the PSI core. This indicates a unique feature of the carotenoid composition of the Lhcr proteins and may suggest an important role of Zea in the light-harvesting and photoprotection of the red algal PSI-LHCI complex.

  11. Handbook of Super 8 Production.

    Science.gov (United States)

    Telzer, Ronnie, Ed.

    This handbook is designed for anyone interested in producing super 8 films at any level of complexity and cost. Separate chapters present detailed discussions of the following topics: super 8 production systems and super 8 shooting and editing systems; budgeting; cinematography and sound recording; preparing to edit; editing; mixing sound tracks;…

  12. Are Complex Magnetic Field Structures Responsible for the Confined X-class Flares in Super Active Region 12192?

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Jun; Li, Ting; Chen, Huadong, E-mail: zjun@nao.cas.cn, E-mail: hdchen@nao.cas.cn [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

    2017-08-10

    From 2014 October 19 to 27, six X-class flares occurred in super active region (AR) 12192. They were all confined flares and were not followed by coronal mass ejections. To examine the structures of the four flares close to the solar disk center from October 22 to 26, we firstly employ composite triple-time images in each flare process to display the stratified structure of these flare loops. The loop structures of each flare in both the lower (171 Å) and higher (131 Å) temperature channels are complex, e.g., the flare loops rooting at flare ribbons are sheared or twisted (enwound) together, and the complex structures were not destroyed during the flares. For the first flare, although the flare loop system appears as a spindle shape, we can estimate its structures from observations, with lengths ranging from 130 to 300 Mm, heights from 65 to 150 Mm, widths at the middle part of the spindle from 40 to 100 Mm, and shear angles from 16° to 90°. Moreover, the flare ribbons display irregular movements, such as the left ribbon fragments of the flare on October 22 sweeping a small region repeatedly, and both ribbons of the flare on October 26 moved along the same direction instead of separating from each other. These irregular movements also imply that the corresponding flare loops are complex, e.g., several sets of flare loops are twisted together. Although previous studies have suggested that the background magnetic fields prevent confined flares from erupting,based on these observations, we suggest that complex flare loop structures may be responsible for these confined flares.

  13. Synthesis of Elongated Microcapsules

    Science.gov (United States)

    Li, Wenyan; Buhrow, Jerry; Calle, Luz M.

    2011-01-01

    One of the factors that influence the effectiveness of self-healing in functional materials is the amount of liquid healing agents that can be delivered to the damaged area. The use of hollow tubes or fibers and the more sophisticated micro-vascular networks has been proposed as a way to increase the amount of healing agents that can be released when damage is inflicted. Although these systems might be effective in some specific applications, they are not practical for coatings applications. One possible practical way to increase the healing efficiency is to use microcapsules with high-aspect-ratios, or elongated microcapsules. It is understood that elongated microcapsules will be more efficient because they can release more healing agent than a spherical microcapsule when a crack is initiated in the coating. Although the potential advantage of using elongated microcapsules for self healing applications is clear, it is very difficult to make elongated microcapsules from an emulsion system because spherical microcapsules are normally formed due to the interfacial tension between the dispersed phase and the continuous phase. This paper describes the two methods that have been developed by the authors to synthesize elongated microcapsules. The first method involves the use of an emulsion with intermediate stability and the second involves the application of mechanical shear conditions to the emulsion.

  14. Elongation of Flare Ribbons

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, Jiong; Longcope, Dana W. [Department of Physics, Montana State University, Bozeman MT (United States); Cassak, Paul A. [Department of Physics and Astronomy, West Virginia University, Morgantown WV (United States); Priest, Eric R. [School of Mathematics and Statistics, University of St. Andrews, Fife KY16 9SS, Scotland (United Kingdom)

    2017-03-20

    We present an analysis of the apparent elongation motion of flare ribbons along the polarity inversion line (PIL), as well as the shear of flare loops in several two-ribbon flares. Flare ribbons and loops spread along the PIL at a speed ranging from a few to a hundred km s{sup −1}. The shear measured from conjugate footpoints is consistent with the measurement from flare loops, and both show the decrease of shear toward a potential field as a flare evolves and ribbons and loops spread along the PIL. Flares exhibiting fast bidirectional elongation appear to have a strong shear, which may indicate a large magnetic guide field relative to the reconnection field in the coronal current sheet. We discuss how the analysis of ribbon motion could help infer properties in the corona where reconnection takes place.

  15. Super-quantum curves from super-eigenvalue models

    Energy Technology Data Exchange (ETDEWEB)

    Ciosmak, Paweł [Faculty of Mathematics, Informatics and Mechanics, University of Warsaw,ul. Banacha 2, 02-097 Warsaw (Poland); Hadasz, Leszek [M. Smoluchowski Institute of Physics, Jagiellonian University,ul. Łojasiewicza 11, 30-348 Kraków (Poland); Manabe, Masahide [Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Sułkowski, Piotr [Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E. California Blvd, Pasadena, CA 91125 (United States)

    2016-10-10

    In modern mathematical and theoretical physics various generalizations, in particular supersymmetric or quantum, of Riemann surfaces and complex algebraic curves play a prominent role. We show that such supersymmetric and quantum generalizations can be combined together, and construct supersymmetric quantum curves, or super-quantum curves for short. Our analysis is conducted in the formalism of super-eigenvalue models: we introduce β-deformed version of those models, and derive differential equations for associated α/β-deformed super-matrix integrals. We show that for a given model there exists an infinite number of such differential equations, which we identify as super-quantum curves, and which are in one-to-one correspondence with, and have the structure of, super-Virasoro singular vectors. We discuss potential applications of super-quantum curves and prospects of other generalizations.

  16. Super-quantum curves from super-eigenvalue models

    International Nuclear Information System (INIS)

    Ciosmak, Paweł; Hadasz, Leszek; Manabe, Masahide; Sułkowski, Piotr

    2016-01-01

    In modern mathematical and theoretical physics various generalizations, in particular supersymmetric or quantum, of Riemann surfaces and complex algebraic curves play a prominent role. We show that such supersymmetric and quantum generalizations can be combined together, and construct supersymmetric quantum curves, or super-quantum curves for short. Our analysis is conducted in the formalism of super-eigenvalue models: we introduce β-deformed version of those models, and derive differential equations for associated α/β-deformed super-matrix integrals. We show that for a given model there exists an infinite number of such differential equations, which we identify as super-quantum curves, and which are in one-to-one correspondence with, and have the structure of, super-Virasoro singular vectors. We discuss potential applications of super-quantum curves and prospects of other generalizations.

  17. Super-quantum curves from super-eigenvalue models

    Science.gov (United States)

    Ciosmak, Paweł; Hadasz, Leszek; Manabe, Masahide; Sułkowski, Piotr

    2016-10-01

    In modern mathematical and theoretical physics various generalizations, in particular supersymmetric or quantum, of Riemann surfaces and complex algebraic curves play a prominent role. We show that such supersymmetric and quantum generalizations can be combined together, and construct supersymmetric quantum curves, or super-quantum curves for short. Our analysis is conducted in the formalism of super-eigenvalue models: we introduce β-deformed version of those models, and derive differential equations for associated α/ β-deformed super-matrix integrals. We show that for a given model there exists an infinite number of such differential equations, which we identify as super-quantum curves, and which are in one-to-one correspondence with, and have the structure of, super-Virasoro singular vectors. We discuss potential applications of super-quantum curves and prospects of other generalizations.

  18. Super jackstraws and super waterwheels

    International Nuclear Information System (INIS)

    Cho, Jin-Ho

    2007-01-01

    We construct various new BPS states of D-branes preserving 8 supersymmetries. These include super Jackstraws (a bunch of scattered D- or (p, q)-strings preserving supersymmetries), and super waterwheels (a number of D2-branes intersecting at generic angles on parallel lines while preserving supersymmetries). Super D-Jackstraws are scattered in various dimensions but are dynamical with all their intersections following a common null direction. Meanwhile, super (p, q)-Jackstraws form a planar static configuration. We show that the SO(2) subgroup of SL(2, R), the group of classical S-duality transformations in IIB theory, can be used to generate this latter configuration of variously charged (p, q)-strings intersecting at various angles. The waterwheel configuration of D2-branes preserves 8 supersymmetries as long as the 'critical' Born-Infeld electric fields are along the common direction

  19. Super differential forms on super Riemann surfaces

    International Nuclear Information System (INIS)

    Konisi, Gaku; Takahasi, Wataru; Saito, Takesi.

    1994-01-01

    Line integral on the super Riemann surface is discussed. A 'super differential operator' which possesses both properties of differential and of differential operator is proposed. With this 'super differential operator' a new theory of differential form on the super Riemann surface is constructed. We call 'the new differentials on the super Riemann surface' 'the super differentials'. As the applications of our theory, the existency theorems of singular 'super differentials' such as 'super abelian differentials of the 3rd kind' and of a super projective connection are examined. (author)

  20. Plant cell wall polysaccharide analysis during cell elongation

    DEFF Research Database (Denmark)

    Guo, Xiaoyuan

    Plant cell walls are complex structures whose composition and architecture are important to various cellular activities. Plant cell elongation requires a high level of rearrangement of the cell wall polymers to enable cell expansion. However, the cell wall polysaccharides dynamics during plant cell...... elongation is poorly understood. This PhD project aims to elucidate the cell wall compositional and structural change during cell elongation by using Comprehensive Microarray Polymer Profiling (CoMPP), microscopic techniques and molecular modifications of cell wall polysaccharide. Developing cotton fibre......, pea and Arabidopsis thaliana were selected as research models to investigate different types of cell elongation, developmental elongation and tropism elongation. A set of comprehensive analysis covering 4 cotton species and 11 time points suggests that non-cellulosic polysaccharides contribute...

  1. Super families

    International Nuclear Information System (INIS)

    Amato, N.; Maldonado, R.H.C.

    1989-01-01

    The study on phenomena in the super high energy region, Σ E j > 1000 TeV revealed events that present a big dark spot in central region with high concentration of energy and particles, called halo. Six super families with halo were analysed by Brazil-Japan Cooperation of Cosmic Rays. For each family the lateral distribution of energy density was constructed and R c Σ E (R c ) was estimated. For studying primary composition, the energy correlation with particles released separately in hadrons and gamma rays was analysed. (M.C.K.)

  2. Elongated membrane tethers, individually anchored by high affinity α4β1/VCAM-1 complexes, are the quantal units of monocyte arrests.

    Directory of Open Access Journals (Sweden)

    Calvin Chu

    Full Text Available The α4β1 integrin facilitates both monocyte rolling and adhesion to the vascular endothelium and is physiologically activated by monocyte chemoattractant protein (MCP-1. The current study investigated the initial events in the adhesion of THP-1 cells to immobilized Vascular Cell Adhesion Molecule 1 (VCAM-1. Using AFM force measurements, cell adhesion was shown to be mediated by two populations of α4β1/VCAM-1 complexes. A low affinity form of α4β1 was anchored to the elastic elements of the cytoskeleton, while a higher affinity conformer was coupled to the viscous elements of the cell membrane. Within 100 ms of contact, THP-1 cells, stimulated by co-immobilized MCP-1, exhibited a tremendous increase in adhesion to VCAM-1. Enhanced cell adhesion was accompanied by a local decoupling of the cell membrane from the cytoskeleton and the formation of long membrane tethers. The tethers were individually anchored by multiple α4β1/VCAM-1 complexes that prolonged the extension of the viscous tethers. In vivo, the formation of these membrane tethers may provide the quantal structural units for the arrest of rolling monocytes within the blood vessels.

  3. Development of a PCR-RFLP method based on the transcription elongation factor 1-α gene to differentiate Fusarium graminearum from other species within the Fusarium graminearum species complex.

    Science.gov (United States)

    Garmendia, Gabriela; Umpierrez-Failache, Mariana; Ward, Todd J; Vero, Silvana

    2018-04-01

    Fusarium head blight (FHB) is a destructive disease of cereals crops worldwide and a major food safety concern due to grain contamination with trichothecenes and other mycotoxins. Fusarium graminearum, a member of the Fusarium graminearum species complex (FGSC) is the dominant FHB pathogen in many parts of the world. However, a number of other Fusarium species, including other members of the FGSC, may also be present for example in Argentina, New Zealand, Ethiopia, Nepal, Unites States in cereals such as wheat and barley. Proper species identification is critical to research aimed at improving disease and mycotoxin control programs. Identification of Fusarium species is are often unreliable by traditional, as many species are morphologically cryptic. DNA sequence-based methods offer a reliable means of species identification, but can be expensive when applied to the analyses of population samples. To facilitate identification of the major causative agent of FHB, this work describes an easy and inexpensive method to differentiate F. graminearum from the remaining species within the FGSC and from the other common Fusarium species causing FHB in cereals. The developed method is based on a PCR-RFLP of the transcription elongation factor (TEF 1-α) gene using the restriction enzyme BsaHI. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. The Super Patalan Numbers

    OpenAIRE

    Richardson, Thomas M.

    2014-01-01

    We introduce the super Patalan numbers, a generalization of the super Catalan numbers in the sense of Gessel, and prove a number of properties analagous to those of the super Catalan numbers. The super Patalan numbers generalize the super Catalan numbers similarly to how the Patalan numbers generalize the Catalan numbers.

  5. Ab Initio investigation of chloroaqualead (II) complexes as possible corrosion products in Super Critical Water Cooled Reactor (SCWR)

    Energy Technology Data Exchange (ETDEWEB)

    Anzelj, D.; Pye, C.C., E-mail: diki1979@hotmail.com, E-mail: cory.pye@smu.ca [Saint Mary' s University, Halifax, NS (Canada)

    2015-07-01

    One of the undesirable processes hindering development of Generation IV SCWR is the possibility of corrosion of construction material. Formation of corrosion products such as metal-ligand complexes is poorly understood both experimentally and computationally. It is essential to predict and control its water chemistry to ensure sustainability of SCWR. Pressurized and heated solutions are challenging for experimental research; computational method becomes an important research tool. A series of ab initio calculations of chloroaqualead (II) complexes have been performed at HF, MP2 and B3LYP levels of theory with CEP-121G, LANL2DZ, SDD basis sets for Pb and 6-31G*, 6-31+G*, 6-311+G* for water. (author)

  6. Ab Initio investigation of chloroaqualead (II) complexes as possible corrosion products in Super Critical Water Cooled Reactor (SCWR)

    International Nuclear Information System (INIS)

    Anzelj, D.; Pye, C.C.

    2015-01-01

    One of the undesirable processes hindering development of Generation IV SCWR is the possibility of corrosion of construction material. Formation of corrosion products such as metal-ligand complexes is poorly understood both experimentally and computationally. It is essential to predict and control its water chemistry to ensure sustainability of SCWR. Pressurized and heated solutions are challenging for experimental research; computational method becomes an important research tool. A series of ab initio calculations of chloroaqualead (II) complexes have been performed at HF, MP2 and B3LYP levels of theory with CEP-121G, LANL2DZ, SDD basis sets for Pb and 6-31G*, 6-31+G*, 6-311+G* for water. (author)

  7. A super soliton connection

    International Nuclear Information System (INIS)

    Gurses, M.; Oguz, O.

    1985-07-01

    Integrable super non-linear classical partial differential equations are considered. A super s1(2,R) algebra valued connection 1-form is constructed. It is shown that curvature 2-form of this super connection vanishes by virtue of the integrable super equations of motion. A super extension of the AKNS scheme is presented and a class of super extension of the Lax hierarchy and super non-linear Schroedinger equation are found. O(N) extension and the Baecklund transformations of the above super equations are also considered. (author)

  8. Nanobodies: site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation

    Science.gov (United States)

    Pleiner, Tino; Bates, Mark; Trakhanov, Sergei; Lee, Chung-Tien; Schliep, Jan Erik; Chug, Hema; Böhning, Marc; Stark, Holger; Urlaub, Henning; Görlich, Dirk

    2015-01-01

    Nanobodies are single-domain antibodies of camelid origin. We generated nanobodies against the vertebrate nuclear pore complex (NPC) and used them in STORM imaging to locate individual NPC proteins with nanobody sequence and labeled the resulting proteins with fluorophore-maleimides. As nanobodies are normally stabilized by disulfide-bonded cysteines, this appears counterintuitive. Yet, our analysis showed that this caused no folding problems. Compared to traditional NHS ester-labeling of lysines, the cysteine-maleimide strategy resulted in far less background in fluorescence imaging, it better preserved epitope recognition and it is site-specific. We also devised a rapid epitope-mapping strategy, which relies on crosslinking mass spectrometry and the introduced ectopic cysteines. Finally, we used different anti-nucleoporin nanobodies to purify the major NPC building blocks – each in a single step, with native elution and, as demonstrated, in excellent quality for structural analysis by electron microscopy. The presented strategies are applicable to any nanobody and nanobody-target. DOI: http://dx.doi.org/10.7554/eLife.11349.001 PMID:26633879

  9. Super-resolution Phase Tomography

    KAUST Repository

    Depeursinge, Christian; Cotte, Yann; Toy, Fatih; Jourdain, Pascal; Boss, Daiel; Marquet, Pierre; Magistretti, Pierre J.

    2013-01-01

    Digital Holographic Microscopy (DHM) yields reconstructed complex wavefields. It allows synthesizing the aperture of a virtual microscope up to 2π, offering super-resolution phase images. Live images of micro-organisms and neurons with resolution less than 100 nm are presented.

  10. Super-resolution Phase Tomography

    KAUST Repository

    Depeursinge, Christian

    2013-04-21

    Digital Holographic Microscopy (DHM) yields reconstructed complex wavefields. It allows synthesizing the aperture of a virtual microscope up to 2π, offering super-resolution phase images. Live images of micro-organisms and neurons with resolution less than 100 nm are presented.

  11. Super(210) Pb based trace element fluxes in the nearshore and estuarine sediments off Bombay, India

    Digital Repository Service at National Institute of Oceanography (India)

    Sharma, P.; Borole, D.V.; Zingde, M.D.

    Seven sediment cores from the Thana Creek-Bombay harbour complex (THC) have been studied for excess super(210) Pb (super(210) Pb sub(exc), that portion of super(210) Pb not supported by decay of super(226) Ra in sediment), C sub(org), Mn, Fe, Co, Ni...

  12. Stochastic model of template-directed elongation processes in biology.

    Science.gov (United States)

    Schilstra, Maria J; Nehaniv, Chrystopher L

    2010-10-01

    We present a novel modular, stochastic model for biological template-based linear chain elongation processes. In this model, elongation complexes (ECs; DNA polymerase, RNA polymerase, or ribosomes associated with nascent chains) that span a finite number of template units step along the template, one after another, with semaphore constructs preventing overtaking. The central elongation module is readily extended with modules that represent initiation and termination processes. The model was used to explore the effect of EC span on motor velocity and dispersion, and the effect of initiation activator and repressor binding kinetics on the overall elongation dynamics. The results demonstrate that (1) motors that move smoothly are able to travel at a greater velocity and closer together than motors that move more erratically, and (2) the rate at which completed chains are released is proportional to the occupancy or vacancy of activator or repressor binding sites only when initiation or activator/repressor dissociation is slow in comparison with elongation. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  13. Supermanifolds and super Riemann surfaces

    International Nuclear Information System (INIS)

    Rabin, J.M.

    1986-09-01

    The theory of super Riemann surfaces is rigorously developed using Rogers' theory of supermanifolds. The global structures of super Teichmueller space and super moduli space are determined. The super modular group is shown to be precisely the ordinary modular group. Super moduli space is shown to be the gauge-fixing slice for the fermionic string path integral

  14. Calculus super review

    CERN Document Server

    2012-01-01

    Get all you need to know with Super Reviews! Each Super Review is packed with in-depth, student-friendly topic reviews that fully explain everything about the subject. The Calculus I Super Review includes a review of functions, limits, basic derivatives, the definite integral, combinations, and permutations. Take the Super Review quizzes to see how much you've learned - and where you need more study. Makes an excellent study aid and textbook companion. Great for self-study!DETAILS- From cover to cover, each in-depth topic review is easy-to-follow and easy-to-grasp - Perfect when preparing for

  15. Algebra & trigonometry super review

    CERN Document Server

    2012-01-01

    Get all you need to know with Super Reviews! Each Super Review is packed with in-depth, student-friendly topic reviews that fully explain everything about the subject. The Algebra and Trigonometry Super Review includes sets and set operations, number systems and fundamental algebraic laws and operations, exponents and radicals, polynomials and rational expressions, equations, linear equations and systems of linear equations, inequalities, relations and functions, quadratic equations, equations of higher order, ratios, proportions, and variations. Take the Super Review quizzes to see how much y

  16. Stability of tokamaks with elongated cross section

    International Nuclear Information System (INIS)

    An, C.H.; Bateman, G.

    1978-08-01

    Fixed boundary n = 1 MHD instabilities are studied computationally as a function of diamagnetism (β/sub pol/) and current profile in elongated toroidal equilibria (1 2) or a diamagnetic plasma (β/sub pol/ > 1) with only a mildly elongated cross section

  17. Translational Control of Cell Division by Elongator

    Directory of Open Access Journals (Sweden)

    Fanelie Bauer

    2012-05-01

    Full Text Available Elongator is required for the synthesis of the mcm5s2 modification found on tRNAs recognizing AA-ending codons. In order to obtain a global picture of the role of Elongator in translation, we used reverse protein arrays to screen the fission yeast proteome for translation defects. Unexpectedly, this revealed that Elongator inactivation mainly affected three specific functional groups including proteins implicated in cell division. The absence of Elongator results in a delay in mitosis onset and cytokinesis defects. We demonstrate that the kinase Cdr2, which is a central regulator of mitosis and cytokinesis, is under translational control by Elongator due to the Lysine codon usage bias of the cdr2 coding sequence. These findings uncover a mechanism by which the codon usage, coupled to tRNA modifications, fundamentally contributes to gene expression and cellular functions.

  18. A study of the super-abundant Bemisia tabaci (Gennadius) species complex (Hemiptera: Aleyrodidae) in cassava Mosaic disease pandemic areas in Tanzania

    DEFF Research Database (Denmark)

    Tajebe, Lensa Sefera

    (Manihot esculenta Crantz) – one of the most important food security crops in sub-Saharan Africa. After the outbreak and spread of a severe form of CMD from Uganda to several East and African countries, the production of cassava has been impaired causing severe yield loss resulting in food shortages....../Hamiltonella/Wolbachia with Arsenophonus or Cardinium. Similarly, double and multiple infections were also common in the IO and EA1 putative species where EA1 individuals commonly harboured Cardinium/Wolbachia with several additional combinations of Rickettsia, Hamiltonella or Arsenophonus. The secondary endosymbiont Fritschea was never...... in the area in general and in understanding this super-abundant pandemicassociated population in particular. Specific studies to assess the presence of other secondary endosymbionts, antibiotic treatments to eliminate certain endosymbionts or to artificially introduce endosymbionts are paramount to fully...

  19. The journey of integrins and partners in a complex interactions landscape studied by super-resolution microscopy and single protein tracking

    International Nuclear Information System (INIS)

    Rossier, Olivier; Giannone, Grégory

    2016-01-01

    Cells adjust their adhesive and cytoskeletal organizations according to changes in the biochemical and physical nature of their surroundings. In return, by adhering and generating forces on the extracellular matrix (ECM) cells organize their microenvironment. Integrin-dependent focal adhesions (FAs) are the converging zones integrating biochemical and biomechanical signals arising from the ECM and the actin cytoskeleton. Thus, integrin-mediated adhesion and mechanotransduction, the conversion of mechanical forces into biochemical signals, are involved in critical cellular functions such as migration, proliferation and differentiation, and their deregulation contributes to pathologies including cancer. A challenging problem is to decipher how stochastic protein movements and interactions lead to formation of dynamic architecture such as integrin-dependent adhesive structures. In this review, we will describe recent advances made possible by super-resolution microscopies and single molecule tracking approaches that provided new understanding on the organization and the dynamics of integrins and intracellular regulators at the nanoscale in living cells.

  20. The journey of integrins and partners in a complex interactions landscape studied by super-resolution microscopy and single protein tracking

    Energy Technology Data Exchange (ETDEWEB)

    Rossier, Olivier; Giannone, Grégory [Univ. Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, F-33000 Bordeaux (France); CNRS, Interdisciplinary Institute for Neuroscience, UMR 5297, F-33000 Bordeaux (France)

    2016-04-10

    Cells adjust their adhesive and cytoskeletal organizations according to changes in the biochemical and physical nature of their surroundings. In return, by adhering and generating forces on the extracellular matrix (ECM) cells organize their microenvironment. Integrin-dependent focal adhesions (FAs) are the converging zones integrating biochemical and biomechanical signals arising from the ECM and the actin cytoskeleton. Thus, integrin-mediated adhesion and mechanotransduction, the conversion of mechanical forces into biochemical signals, are involved in critical cellular functions such as migration, proliferation and differentiation, and their deregulation contributes to pathologies including cancer. A challenging problem is to decipher how stochastic protein movements and interactions lead to formation of dynamic architecture such as integrin-dependent adhesive structures. In this review, we will describe recent advances made possible by super-resolution microscopies and single molecule tracking approaches that provided new understanding on the organization and the dynamics of integrins and intracellular regulators at the nanoscale in living cells.

  1. FtsZ-Dependent Elongation of a Coccoid Bacterium

    Directory of Open Access Journals (Sweden)

    Ana R. Pereira

    2016-09-01

    Full Text Available A mechanistic understanding of the determination and maintenance of the simplest bacterial cell shape, a sphere, remains elusive compared with that of more complex shapes. Cocci seem to lack a dedicated elongation machinery, and a spherical shape has been considered an evolutionary dead-end morphology, as a transition from a spherical to a rod-like shape has never been observed in bacteria. Here we show that a Staphylococcus aureus mutant (M5 expressing the ftsZG193D allele exhibits elongated cells. Molecular dynamics simulations and in vitro studies indicate that FtsZG193D filaments are more twisted and shorter than wild-type filaments. In vivo, M5 cell wall deposition is initiated asymmetrically, only on one side of the cell, and progresses into a helical pattern rather than into a constricting ring as in wild-type cells. This helical pattern of wall insertion leads to elongation, as in rod-shaped cells. Thus, structural flexibility of FtsZ filaments can result in an FtsZ-dependent mechanism for generating elongated cells from cocci.

  2. The life and death of translation elongation factor 2

    DEFF Research Database (Denmark)

    Jørgensen, Rene; Merrill, A.R.; Andersen, Gregers Rom

    2006-01-01

    The eukaryotic elongation factor 2 (eEF2) occupies an essential role in protein synthesis where it catalyses the translocation of the two tRNAs and the mRNA after peptidyl transfer on the 80S ribosome. Recent crystal structures of eEF2 and the cryo-EM reconstruction of its 80S complex now provide...... diphthamide residue, which is ADP-ribosylated by diphtheria toxin from Corynebacterium diphtheriae and exotoxin A from Pseudomonas aeruginosa....

  3. Nonlinear Super Integrable Couplings of Super Classical-Boussinesq Hierarchy

    Directory of Open Access Journals (Sweden)

    Xiuzhi Xing

    2014-01-01

    Full Text Available Nonlinear integrable couplings of super classical-Boussinesq hierarchy based upon an enlarged matrix Lie super algebra were constructed. Then, its super Hamiltonian structures were established by using super trace identity. As its reduction, nonlinear integrable couplings of the classical integrable hierarchy were obtained.

  4. The journey of integrins and partners in a complex interactions landscape studied by super-resolution microscopy and single protein tracking.

    Science.gov (United States)

    Rossier, Olivier; Giannone, Grégory

    2016-04-10

    Cells adjust their adhesive and cytoskeletal organizations according to changes in the biochemical and physical nature of their surroundings. In return, by adhering and generating forces on the extracellular matrix (ECM) cells organize their microenvironment. Integrin-dependent focal adhesions (FAs) are the converging zones integrating biochemical and biomechanical signals arising from the ECM and the actin cytoskeleton. Thus, integrin-mediated adhesion and mechanotransduction, the conversion of mechanical forces into biochemical signals, are involved in critical cellular functions such as migration, proliferation and differentiation, and their deregulation contributes to pathologies including cancer. A challenging problem is to decipher how stochastic protein movements and interactions lead to formation of dynamic architecture such as integrin-dependent adhesive structures. In this review, we will describe recent advances made possible by super-resolution microscopies and single molecule tracking approaches that provided new understanding on the organization and the dynamics of integrins and intracellular regulators at the nanoscale in living cells. Copyright © 2015. Published by Elsevier Inc.

  5. Uniaxial Elongational viscosity of bidisperse polystyrene melts

    DEFF Research Database (Denmark)

    Nielsen, Jens Kromann; Rasmussen, Henrik K.; Hassager, Ole

    2006-01-01

    The startup and steady uniaxial elongational viscosity have been measured for three bidisperse polystyrene (PS) melts, consisting of blends of monodisperse PS with molecular weights of 52 kg/mole or 103 kg/mole and 390 kg/mole. The bidisperse melts have a maximum in the steady elongational...... viscosity, of up to a factor of 7 times the Trouton limit of 3 times the zero-shear viscosity....

  6. Planar Elongation Measurements on Soft Elastomers

    DEFF Research Database (Denmark)

    Jensen, Mette Krog; Skov, Anne Ladegaard; Rasmussen, Henrik K.

    2009-01-01

    A new fixture to the filament stretch rheometer (FSR) has been developed to measure planar elongation of soft polymeric networks. To validate this new technique, soft polymeric networks of poly(propyleneoxide) (PPO) were investigated during deformation.......A new fixture to the filament stretch rheometer (FSR) has been developed to measure planar elongation of soft polymeric networks. To validate this new technique, soft polymeric networks of poly(propyleneoxide) (PPO) were investigated during deformation....

  7. Mutual interdependence of splicing and transcription elongation.

    Science.gov (United States)

    Brzyżek, Grzegorz; Świeżewski, Szymon

    2015-01-01

    Transcription and splicing are intrinsically linked, as splicing needs a pre-mRNA substrate to commence. The more nuanced view is that the rate of transcription contributes to splicing regulation. On the other hand there is accumulating evidence that splicing has an active role in controlling transcription elongation by DNA-dependent RNA polymerase II (RNAP II). We briefly review those mechanisms and propose a unifying model where splicing controls transcription elongation to provide an optimal timing for successive rounds of splicing.

  8. Super periodic potential

    Science.gov (United States)

    Hasan, Mohammd; Mandal, Bhabani Prasad

    2018-04-01

    In this paper we introduce the concept of super periodic potential (SPP) of arbitrary order n, n ∈I+, in one dimension. General theory of wave propagation through SPP of order n is presented and the reflection and transmission coefficients are derived in their closed analytical form by transfer matrix formulation. We present scattering features of super periodic rectangular potential and super periodic delta potential as special cases of SPP. It is found that the symmetric self-similarity is the special case of super periodicity. Thus by identifying a symmetric fractal potential as special cases of SPP, one can obtain the tunnelling amplitude for a particle from such fractal potential. By using the formalism of SPP we obtain the close form expression of tunnelling amplitude of a particle for general Cantor and Smith-Volterra-Cantor potentials.

  9. NETL Super Computer

    Data.gov (United States)

    Federal Laboratory Consortium — The NETL Super Computer was designed for performing engineering calculations that apply to fossil energy research. It is one of the world’s larger supercomputers,...

  10. Super-resolution imaging visualizes the eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution

    NARCIS (Netherlands)

    Löschberger, A.; Van de Linde, S.; Debauvalle, M.C.; Rieger, B.; Heilemann, M.; Krohne, G.; Sauer, M.

    2012-01-01

    One of the most complex molecular machines of cells is the nuclear pore complex (NPC), which controls all trafficking of molecules in and out of the nucleus. Because of their importance for cellular processes such as gene expression and cytoskeleton organization, the structure of NPCs has been

  11. Elongational viscosity of narrow molar mass distribution polystyrene

    DEFF Research Database (Denmark)

    Bach, Anders; Almdal, Kristoffer; Rasmussen, Henrik Koblitz

    2003-01-01

    Transient and steady elongational viscosity has been measured for two narrow molar mass distribution polystyrene melts of molar masses 200 000 and 390 000 by means of a filament stretching rheometer. Total Hencky strains of about five have been obtained. The transient elongational viscosity rises...... above the linear viscoelastic prediction at intermediate strains, indicating strain hardening. The steady elongational viscosities are monotone decreasing functions of elongation rate. At elongation rates larger than the inverse reptation time, the steady elongational viscosity scales linearly...

  12. Microscale Synthesis, Reactions, and (Super 1)H NMR Spectroscopic Investigations of Square Planar Macrocyclic, Tetramido-N Co(III) Complexes Relevant to Green Chemistry

    Science.gov (United States)

    Watson, Tanya T.; Uffelman, Erich S.; Lee, Daniel W., III; Doherty, Jonathan R.; Schulze, Carl; Burke, Amy L.; Bonnema, Kristen, R.

    2004-01-01

    The microscale preparation, characterization, and reactivity of a square planar Co(III) complex that has grown out of a program to introduce experiments of relevance to green chemistry into the undergraduate curriculum is presented. The given experiments illustrate the remarkable redox and aqueous acid-base stability that make the macrocycles very…

  13. Scatter factor corrections for elongated fields

    International Nuclear Information System (INIS)

    Higgins, P.D.; Sohn, W.H.; Sibata, C.H.; McCarthy, W.A.

    1989-01-01

    Measurements have been made to determine scatter factor corrections for elongated fields of Cobalt-60 and for nominal linear accelerator energies of 6 MV (Siemens Mevatron 67) and 18 MV (AECL Therac 20). It was found that for every energy the collimator scatter factor varies by 2% or more as the field length-to-width ratio increases beyond 3:1. The phantom scatter factor is independent of which collimator pair is elongated at these energies. For 18 MV photons it was found that the collimator scatter factor is complicated by field-size-dependent backscatter into the beam monitor

  14. Performing the Super Instrument

    DEFF Research Database (Denmark)

    Kallionpaa, Maria

    2016-01-01

    can empower performers by producing super instrument works that allow the concert instrument to become an ensemble controlled by a single player. The existing instrumental skills of the performer can be multiplied and the qualities of regular acoustic instruments extended or modified. Such a situation......The genre of contemporary classical music has seen significant innovation and research related to new super, hyper, and hybrid instruments, which opens up a vast palette of expressive potential. An increasing number of composers, performers, instrument designers, engineers, and computer programmers...... have become interested in different ways of “supersizing” acoustic instruments in order to open up previously-unheard instrumental sounds. Super instruments vary a great deal but each has a transformative effect on the identity and performance practice of the performing musician. Furthermore, composers...

  15. Raspberry Pi super cluster

    CERN Document Server

    Dennis, Andrew K

    2013-01-01

    This book follows a step-by-step, tutorial-based approach which will teach you how to develop your own super cluster using Raspberry Pi computers quickly and efficiently.Raspberry Pi Super Cluster is an introductory guide for those interested in experimenting with parallel computing at home. Aimed at Raspberry Pi enthusiasts, this book is a primer for getting your first cluster up and running.Basic knowledge of C or Java would be helpful but no prior knowledge of parallel computing is necessary.

  16. The super-resolution debate

    Science.gov (United States)

    Won, Rachel

    2018-05-01

    In the quest for nanoscopy with super-resolution, consensus from the imaging community is that super-resolution is not always needed and that scientists should choose an imaging technique based on their specific application.

  17. Segmentation of elongated structures in medical images

    NARCIS (Netherlands)

    Staal, Jozef Johannes

    2004-01-01

    The research described in this thesis concerns the automatic detection, recognition and segmentation of elongated structures in medical images. For this purpose techniques have been developed to detect subdimensional pointsets (e.g. ridges, edges) in images of arbitrary dimension. These

  18. Rhizome elongation and seagrass clonal growth

    NARCIS (Netherlands)

    Marbà, N.; Duarte, C.M.

    1998-01-01

    A compilation of published and original data on rhizome morphometry, horizontal and vertical elongation rates and branching patterns for 27 seagrass species developing in 192 seagrass stands allowed an examination of the variability of seagrass rhizome and clonal growth programmes across and within

  19. Interplay between DNA supercoiling and transcription elongation.

    Science.gov (United States)

    Ma, Jie; Wang, Michelle

    2014-01-01

    Transcription-coupled DNA supercoiling has been shown to be an important regulator of transcription that is broadly present in the cell. Here we review experimental work which shows that RNA polymerase is a powerful torsional motor that can alter DNA topology and structure, and DNA supercoiling in turn directly affects transcription elongation.

  20. Frames in super Hilbert modules

    Directory of Open Access Journals (Sweden)

    Mehdi Rashidi-Kouchi

    2018-01-01

    Full Text Available In this paper, we define super Hilbert module and investigate frames in this space. Super Hilbert modules are  generalization of super Hilbert spaces in Hilbert C*-module setting. Also, we define frames in a super Hilbert module and characterize them by using of the concept of g-frames in a Hilbert C*-module. Finally, disjoint frames in Hilbert C*-modules are introduced and investigated.

  1. Super-resolution

    DEFF Research Database (Denmark)

    Nasrollahi, Kamal; Moeslund, Thomas B.

    2014-01-01

    Super-resolution, the process of obtaining one or more high-resolution images from one or more low-resolution observations, has been a very attractive research topic over the last two decades. It has found practical applications in many real world problems in different fields, from satellite...

  2. Superconducting Super Collider project

    International Nuclear Information System (INIS)

    Perl, M.L.

    1986-04-01

    The scientific need for the Superconducting Super Collider (SSC) is outlined, along with the history of the development of the SSC concept. A brief technical description is given of each of the main points of the SSC conceptual design. The construction cost and construction schedule are discussed, followed by issues associated with the realization of the SSC. 8 refs., 3 figs., 3 tabs

  3. Super Refractory Status Epilepticus

    African Journals Online (AJOL)

    user

    et al did retrospective cohort study from 1 January st. 1994 to 31 March 1998 at Presbyterian Medical. Centre in Columbia, to determine the frequency, risk factors and impact on the outcome of RSE. They found out that 69% of seizures recurred after. Key Words: Super refractory status epilepticus, Zambia. Medical Journal of ...

  4. Optimal Super Dielectric Material

    Science.gov (United States)

    2015-09-01

    plate capacitor will reduce the net field to an unprecedented extent. This family of materials can form materials with dielectric values orders of... Capacitor -Increase Area (A)............8 b. Multi-layer Ceramic Capacitor -Decrease Thickness (d) .......10 c. Super Dielectric Material-Increase...circuit modeling, from [44], and B) SDM capacitor charge and discharge ...................................................22 Figure 15. Dielectric

  5. SuperHILAC

    International Nuclear Information System (INIS)

    Nemetz, R.; Selph, F.; Barnes, A.C.

    1976-01-01

    A brief discussion is given of improvements, operations, and research programs at the SuperHILAC. Improvements were made in beam injection, ion sources, and computer control systems. The research efficiency ranged between 70 and 90 percent during most of the year

  6. SuperFormLab: showing SuperFormLab

    DEFF Research Database (Denmark)

    2013-01-01

    bachelor program, followed by two years of master studies. The courses are offered equally to students from other design disciplines, e.g. industrial design. Teaching is mainly in English as the program is attended by a relatively large group of non-Danish students, who seek exactly this combination......3D-printing in clay and ceramic objects shaped by your own sounds and movements! Digital form transferred via CNC-milling to ornamental ceramic wall-cladding. Brave New World… Students and their teacher at SuperFormLab, the new ceramic workshop of the School of Design at the Royal Danish Academy...... of Fine Arts in Copenhagen, will be showing results of their investigations into the potential of combining digital technologies with ceramic materials. It is now possible to shape the most complex mathematical, virtual 3D objects through the use of advanced software-programs. And more than that – you can...

  7. Transcription elongation factor GreA has functional chaperone activity.

    Science.gov (United States)

    Li, Kun; Jiang, Tianyi; Yu, Bo; Wang, Limin; Gao, Chao; Ma, Cuiqing; Xu, Ping; Ma, Yanhe

    2012-01-01

    Bacterial GreA is an indispensable factor in the RNA polymerase elongation complex. It plays multiple roles in transcriptional elongation, and may be implicated in resistance to various stresses. In this study, we show that Escherichia coli GreA inhibits aggregation of several substrate proteins under heat shock condition. GreA can also effectively promote the refolding of denatured proteins. These facts reveal that GreA has chaperone activity. Distinct from many molecular chaperones, GreA does not form stable complexes with unfolded substrates. GreA overexpression confers the host cells with enhanced resistance to heat shock and oxidative stress. Moreover, GreA expression in the greA/greB double mutant could suppress the temperature-sensitive phenotype, and dramatically alleviate the in vivo protein aggregation. The results suggest that bacterial GreA may act as chaperone in vivo. These results suggest that GreA, in addition to its function as a transcription factor, is involved in protection of cellular proteins against aggregation.

  8. Deformations of super Riemann surfaces

    International Nuclear Information System (INIS)

    Ninnemann, H.

    1992-01-01

    Two different approaches to (Konstant-Leites-) super Riemann surfaces are investigated. In the local approach, i.e. glueing open superdomains by superconformal transition functions, deformations of the superconformal structure are discussed. On the other hand, the representation of compact super Riemann surfaces of genus greater than one as a fundamental domain in the Poincare upper half-plane provides a simple description of super Laplace operators acting on automorphic p-forms. Considering purely odd deformations of super Riemann surfaces, the number of linear independent holomorphic sections of arbitrary holomorphic line bundles will be shown to be independent of the odd moduli, leading to a simple proof of the Riemann-Roch theorem for compact super Riemann surfaces. As a further consequence, the explicit connections between determinants of super Laplacians and Selberg's super zeta functions can be determined, allowing to calculate at least the 2-loop contribution to the fermionic string partition function. (orig.)

  9. Deformations of super Riemann surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Ninnemann, H [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    1992-11-01

    Two different approaches to (Konstant-Leites-) super Riemann surfaces are investigated. In the local approach, i.e. glueing open superdomains by superconformal transition functions, deformations of the superconformal structure are discussed. On the other hand, the representation of compact super Riemann surfaces of genus greater than one as a fundamental domain in the Poincare upper half-plane provides a simple description of super Laplace operators acting on automorphic p-forms. Considering purely odd deformations of super Riemann surfaces, the number of linear independent holomorphic sections of arbitrary holomorphic line bundles will be shown to be independent of the odd moduli, leading to a simple proof of the Riemann-Roch theorem for compact super Riemann surfaces. As a further consequence, the explicit connections between determinants of super Laplacians and Selberg's super zeta functions can be determined, allowing to calculate at least the 2-loop contribution to the fermionic string partition function. (orig.).

  10. Sound propagation in elongated superfluid fermionic clouds

    International Nuclear Information System (INIS)

    Capuzzi, P.; Vignolo, P.; Federici, F.; Tosi, M. P.

    2006-01-01

    We use hydrodynamic equations to study sound propagation in a superfluid Fermi gas at zero temperature inside a strongly elongated cigar-shaped trap, with main attention to the transition from the BCS to the unitary regime. First, we treat the role of the radial density profile in the limit of a cylindrical geometry and then evaluate numerically the effect of the axial confinement in a configuration in which a hole is present in the gas density at the center of the trap. We find that in a strongly elongated trap the speed of sound in both the BCS and the unitary regime differs by a factor √(3/5) from that in a homogeneous three-dimensional superfluid. The predictions of the theory could be tested by measurements of sound-wave propagation in a setup such as that exploited by Andrews et al. [Phys. Rev. Lett. 79, 553 (1997)] for an atomic Bose-Einstein condensate

  11. Discontinuation of orthokeratology on eyeball elongation (DOEE).

    Science.gov (United States)

    Cho, P; Cheung, S W

    2017-04-01

    To evaluate and compare changes in axial elongation, over a 14-month period, in subjects who discontinued and then resumed ortho-k lens wear with those who continued to wear their lenses or spectacles following a 2-year myopia control study. This single masked, prospective study recruited subjects who had just completed a 2-year myopia control study. Ortho-k subjects were classified as Group OKc, in which subjects continued ortho-k lens wear for the duration of the study; or Group OKd in which subjects discontinued lens wear for seven months and wore single-vision spectacles (Phase I) and then resumed ortho-k lens wear for another seven months (Phase II). Spectacle-wearing control subjects from the initial myopia control study continued wearing spectacles as control subjects. Axial lengths were measured at scheduled visits using the IOLMaster. Thirteen, 16, and 15 Control, OKc, and OKd subjects, aged 8-14 years, respectively completed the study. Significant increase in axial elongation was found in OKd subjects only in Phase I but not in Phase II. On resuming lens wear, in Phase II, the rate of axial elongation was no longer significantly different from those of the Control or OKc subjects. Stopping ortho-k lens wear at or before the age of 14 years led to a more rapid increase in axial length; comparable to those wearing spectacles during the initial 2-year myopia control study, but greater than the Control and OKc group in this study. Axial elongation slowed again with resumed lens wear after six months. Copyright © 2016 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

  12. XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation

    DEFF Research Database (Denmark)

    Mortuza, Gulnahar B; Cavazza, Tommaso; Garcia-Mayoral, Maria Flor

    2014-01-01

    215 (chTOG), dissecting the mechanism by which their interaction promotes microtubule elongation during spindle assembly. Using SAXS, we show that the TACC domain (TD) is an elongated structure that mediates the interaction with the C terminus of XMAP215. Our data suggest that one TD and two XMAP215...... molecules associate to form a four-helix coiled-coil complex. A hybrid methods approach was used to define the precise regions of the TACC heptad repeat and the XMAP215 C terminus required for assembly and functioning of the complex. We show that XTACC3 can induce the recruitment of larger amounts of XMAP...

  13. Elongational viscosity of photo-oxidated LDPE

    Science.gov (United States)

    Rolón-Garrido, Víctor H.; Wagner, Manfred H.

    2014-05-01

    Sheets of low-density polyethylene (LDPE) were photo-oxidatively treated at room temperature, and subsequently characterized rheologically in the melt state by shear and uniaxial extensional experiments. For photo-oxidation, a xenon lamp was used to irradiate the samples for times between 1 day and 6 weeks. Linear-viscoelastic characterization was performed in a temperature range of 130 to 220°C to obtain the master curve at 170°C, the reference temperature at which the elongational viscosities were measured. Linear viscoelasticity is increasingly affected by increasing photo-oxidation due to crosslinking of LDPE, as corroborated by an increasing gel fraction as determined by a solvent extraction method. The elongational measurements reveal a strong enhancement of strain hardening until a saturation level is achieved. The elongational data are analyzed in the frame work of two constitutive equations, the rubber-like liquid and the molecular stress function models. Within the experimental window, timedeformation separability is confirmed for all samples, independent of the degree of photo-oxidation.

  14. EUROv Super Beam Studies

    International Nuclear Information System (INIS)

    Dracos, Marcos

    2011-01-01

    Neutrino Super Beams use conventional techniques to significantly increase the neutrino beam intensity compared to the present neutrino facilities. An essential part of these facilities is an intense proton driver producing a beam power higher than a MW. The protons hit a target able to accept the high proton beam intensity. The produced charged particles are focused by a system of magnetic horns towards the experiment detectors. The main challenge of these projects is to deal with the high beam intensity for many years. New high power neutrino facilities could be build at CERN profiting from an eventual construction of a high power proton driver. The European FP7 Design Study EUROv, among other neutrino beams, studies this Super Beam possibility. This paper will give the latest developments in this direction.

  15. Super-insulation

    International Nuclear Information System (INIS)

    Gerold, J.

    1985-01-01

    The invention concerns super-insulation, which also acts as spacing between two pressurized surfaces, where the crossing bars in at least two layers are provided, with interposed foil. The super-insulation is designed so that it can take compression forces and limits thermal radiation and thermal conduction sufficiently, where the total density of heat flow is usually limited to a few watts per m 2 . The solution to the problem is characterized by the fact that the bars per layer are parallel and from layer to layer they are at an angle to each other and the crossover positions of the bars of different layers are at fixed places and so form contact columns. The basic idea is that bars crossing over each other to support compression forces are used so that contact columns are formed, which are compressed to a certain extent by the load. (orig./PW) [de

  16. SuperSegger

    DEFF Research Database (Denmark)

    Stylianidou, Stella; Brennan, Connor; Nissen, Silas B

    2016-01-01

    -colonies with many cells, facilitating the analysis of cell-cycle dynamics in bacteria as well as cell-contact mediated phenomena. This package has a range of built-in capabilities for characterizing bacterial cells, including the identification of cell division events, mother, daughter, and neighboring cells......Many quantitative cell biology questions require fast yet reliable automated image segmentation to identify and link cells from frame-to-frame, and characterize the cell morphology and fluorescence. We present SuperSegger, an automated MATLAB-based image processing package well......-suited to quantitative analysis of high-throughput live-cell fluorescence microscopy of bacterial cells. SuperSegger incorporates machine-learning algorithms to optimize cellular boundaries and automated error resolution to reliably link cells from frame-to-frame. Unlike existing packages, it can reliably segment micro...

  17. Super-Lagrangians

    International Nuclear Information System (INIS)

    Beyl, L.M.

    1979-01-01

    It is shown that the Einstein, Weyl, supergravity and superconformal theories are special cases of gauge transformations in SU(4vertical-barN). This group is shown to contain SU(2,2) x SU(N) x U(1) for its commuting or Bose part, and to contain 8N supersymmetry generators for its anticommuting or Fermi part. Using the electromagnetic Lagrangian as a model, a super-Lagrangian is constructed for vector potentials. Invariance is automatic in free space, but, in the presence of matter, restrictions on the supersymmetry transformations are necessary. The Weyl action and the Einstein cosmological field equations are obtained in the appropriate limits. Finally, a super-Lagrangian is constructed from nongeometric principles which includes the Dirac Lagrangian and except for a sum over symmetry indices resembles the electron-electromagnetic Lagrangian

  18. Minimal Super Technicolor

    DEFF Research Database (Denmark)

    Antola, M.; Di Chiara, S.; Sannino, F.

    2011-01-01

    We introduce novel extensions of the Standard Model featuring a supersymmetric technicolor sector (supertechnicolor). As the first minimal conformal supertechnicolor model we consider N=4 Super Yang-Mills which breaks to N=1 via the electroweak interactions. This is a well defined, economical......, between unparticle physics and Minimal Walking Technicolor. We consider also other N =1 extensions of the Minimal Walking Technicolor model. The new models allow all the standard model matter fields to acquire a mass....

  19. Characterising Super-Earths

    Directory of Open Access Journals (Sweden)

    Valencia D.

    2011-02-01

    Full Text Available The era of Super-Earths has formally begun with the detection of transiting low-mass exoplanets CoRoT-7b and GJ 1214b. In the path of characterising super-Earths, the first step is to infer their composition. While the discovery data for CoRoT-7b, in combination with the high atmospheric mass loss rate inferred from the high insolation, suggested that it was a rocky planet, the new proposed mass values have widened the possibilities. The combined mass range 1−10 M⊕ allows for a volatile-rich (and requires it if the mass is less than 4 M⊕ , an Earth-like or a super-Mercury-like composition. In contrast, the radius of GJ 1214b is too large to admit a solid composition, thus it necessarily to have a substantial gas layer. Some evidence suggests that within this gas layer H/He is a small but non-negligible component. These two planets are the first of many transiting low-mass exoplanets expected to be detected and they exemplify the limitations faced when inferring composition, which come from the degenerate character of the problem and the large error bars in the data.

  20. Mapping Escherichia coli elongation factor Tu residues involved in binding of aminoacyl-tRNA

    DEFF Research Database (Denmark)

    Wiborg, Ove; Andersen, C; Knudsen, Charlotte Rohde

    1996-01-01

    Two residues of Escherichia coli elongation factor Tu involved in binding of aminoacyl-tRNA were identified and subjected to mutational analysis. Lys-89 and Asn-90 were each replaced by either Ala or Glu. The four single mutants were denoted K89A, K89E, N90A, and N90E, respectively. The mutants...... were characterized with respect to thermal and chemical stability, GTPase activity, tRNA affinity, and activity in an in vitro translation assay. Most conspicuously tRNA affinities were reduced for all mutants. The results verify our structural analysis of elongation factor Tu in complex with aminoacyl....... Their functional roles are discussed in relation to the structure of elongation factor Tu in complex with aminoacyl-tRNA. Udgivelsesdato: 1996-Aug-23...

  1. Aphidicolin-induced nuclear elongation in tobacco BY-2 cells.

    Science.gov (United States)

    Yasuhara, Hiroki; Kitamoto, Kazuki

    2014-05-01

    Plant nuclei are known to differentiate into various shapes within a single plant. However, little is known about the mechanisms of nuclear morphogenesis. We found that nuclei of tobacco BY-2 cells were highly elongated on long-term treatment with 5 mg l⁻¹ aphidicolin, an inhibitor of DNA polymerase α. In aphidicolin-treated cells, the nuclear length was correlated with the cell length. During culture in the presence of aphidicolin, the nuclei were elongated in parallel with cell elongation. Nuclear elongation was inhibited by the inhibition of cell elongation with 2,6-dichlorobenzonitrile, a cellulose synthesis inhibitor. However, cell elongation induced in the auxin-depleted medium in the absence of aphidicolin did not cause nuclear elongation, indicating that cell elongation alone is not sufficient for nuclear elongation. Treatment with either latrunculin B or propyzamide inhibited the aphidicolin-induced nuclear elongation, indicating that both actin filaments and microtubules (MTs) are required for nuclear elongation. Observations using BY-YTHCLR2 cells, in which actin filaments, MTs and nuclei were simultaneously visualized, revealed that the longitudinally arranged MT bundles associated with the nucleus play an important role in nuclear elongation, and that actin filaments affect the formation of these MT bundles. In aphidicolin-treated cells, the nuclear DNA contents of the elongated nuclei exceeded 4C, and the nuclear length was highly correlated with the nuclear DNA content. In cells treated with 50 mg l⁻¹ aphidicolin, cells were elongated and nucleus-associated longitudinal MT bundles were formed, but the nuclear DNA contents did not exceed 4C and the nuclei did not elongate. These results indicate that an increase in the nuclear DNA content above 4C is also required for nuclear elongation.

  2. Elongational viscosity of monodisperse and bidisperse polystyrene melts

    DEFF Research Database (Denmark)

    Nielsen, Jens Kromann; Rasmussen, Henrik K.; Hassager, Ole

    2006-01-01

    The start-up and steady uniaxial elongational viscosity have been measured for two monodisperse polystyrene melts with molecular weights of 52 and 103 kg/mole, and for three bidisperse polystyrene melts. The monodisperse melts show a maximum in the steady elongational viscosity vs. the elongational...

  3. X chromosome dosage compensation via enhanced transcriptional elongation in Drosophila.

    Science.gov (United States)

    Larschan, Erica; Bishop, Eric P; Kharchenko, Peter V; Core, Leighton J; Lis, John T; Park, Peter J; Kuroda, Mitzi I

    2011-03-03

    The evolution of sex chromosomes has resulted in numerous species in which females inherit two X chromosomes but males have a single X, thus requiring dosage compensation. MSL (Male-specific lethal) complex increases transcription on the single X chromosome of Drosophila males to equalize expression of X-linked genes between the sexes. The biochemical mechanisms used for dosage compensation must function over a wide dynamic range of transcription levels and differential expression patterns. It has been proposed that the MSL complex regulates transcriptional elongation to control dosage compensation, a model subsequently supported by mapping of the MSL complex and MSL-dependent histone 4 lysine 16 acetylation to the bodies of X-linked genes in males, with a bias towards 3' ends. However, experimental analysis of MSL function at the mechanistic level has been challenging owing to the small magnitude of the chromosome-wide effect and the lack of an in vitro system for biochemical analysis. Here we use global run-on sequencing (GRO-seq) to examine the specific effect of the MSL complex on RNA Polymerase II (RNAP II) on a genome-wide level. Results indicate that the MSL complex enhances transcription by facilitating the progression of RNAP II across the bodies of active X-linked genes. Improving transcriptional output downstream of typical gene-specific controls may explain how dosage compensation can be imposed on the diverse set of genes along an entire chromosome.

  4. Theory of super LIE groups

    International Nuclear Information System (INIS)

    Prakash, M.

    1985-01-01

    The theory of supergravity has attracted increasing attention in the recent years as a unified theory of elementary particle interactions. The superspace formulation of the theory is highly suggestive of an underlying geometrical structure of superspace. It also incorporates the beautifully geometrical general theory of relativity. It leads us to believe that a better understanding of its geometry would result in a better understanding of the theory itself, and furthermore, that the geometry of superspace would also have physical consequences. As a first step towards that goal, we develop here a theory of super Lie groups. These are groups that have the same relation to a super Lie algebra as Lie groups have to a Lie algebra. More precisely, a super Lie group is a super-manifold and a group such that the group operations are super-analytic. The super Lie algebra of a super Lie group is related to the local properties of the group near the identity. This work develops the algebraic and super-analytical tools necessary for our theory, including proofs of a set of existence and uniqueness theorems for a class of super-differential equations

  5. JAPAN: Super-Kamiokande

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    Excavation for the Japanese Super- KAMIOKANDE 50,000-ton water Cherenkov imaging detector was completed at the end of June. The goals include a search for nucleon decay up to a lifetime of 10 33-34 years, high-statistics studies of solar and atmospheric neutrinos, and detection of any nearby supernova explosions. The project was approved in 1991, with the official 'groundbreaking' in December of that year about 1,000 m underground in the Kamioka mine in Gifu Prefecture, about 250 km west of Tokyo

  6. The super collider revisited

    International Nuclear Information System (INIS)

    Hussein, M.S.; Pato, M.P.

    1992-01-01

    In this paper, the authors suggest a revised version of the Superconducting Super Collider (SSC) that employs the planned SSC first stage machine as an injector of 0.5 TeV protons into a power laser accelerator. The recently developed Non-linear Amplification of Inverse Bremsstrahlung Acceleration (NAIBA) concept dictates the scenario of the next stage of acceleration. Post Star Wars lasers, available at several laboratories, can be used for the purpose. The 40 TeV CM energy, a target of the SSC, can be obtained with a new machine which can be 20 times smaller than the planned SSC

  7. The super-LHC

    CERN Document Server

    Mangano, Michelangelo L

    2010-01-01

    We review here the prospects of a long-term upgrade programme for the Large Hadron Collider (LHC), CERN laboratory's new proton-proton collider. The super-LHC, which is currently under evaluation and design, is expected to deliver of the order of ten times the statistics of the LHC. In addition to a non-technical summary of the principal physics arguments for the upgrade, I present a pedagogical introduction to the technological challenges on the accelerator and experimental fronts, and a review of the current status of the planning.

  8. Super-heptazethrene

    KAUST Repository

    Zeng, Wangdong

    2016-05-30

    The challenging synthesis of a laterally extended heptazethrene molecule, the super-heptazethrene derivative SHZ-CF3, is reported. This molecule was prepared using a strategy involving a multiple selective intramolecular Friedel–Crafts alkylation followed by oxidative dehydrogenation. Compound SHZ-CF3 exhibits an open-shell singlet diradical ground state with a much larger diradical character compared with the heptazethrene derivatives. An intermediate dibenzo-terrylene SHZ-2H was also obtained during the synthesis. This study provides a new synthetic method to access large-size quinoidal polycyclic hydrocarbons with unique physical properties.

  9. Elongational viscosity of multiarm (Pom-Pom) polystyrene

    DEFF Research Database (Denmark)

    Nielsen, Jens Kromann; Rasmussen, Henrik K.; Almdal, Kristoffer

    2006-01-01

    -Pom was estimated to have 2.5 arms on average, while the estimate is 3.3 for the asymmetric star. The molar mass of each arm is about 27 kg/mol. The melts were characterized in the linear viscoelastic regime and in non-linear elongational rheometry. The transient elongational viscosity for the Pom-Pom molecule...... it corresponds well with an estimate of the maximum stretchability of the backbone. Time-strain separability was not observed for the 'Asymmetric star' molecule at the elongation rates investigated. The transient elongational viscosity for the 'Pom-Pom' molecule went through a reproducible maximum...... in the viscosity at the highest elongational rate....

  10. Super-resolution imaging applied to moving object tracking

    Science.gov (United States)

    Swalaganata, Galandaru; Ratna Sulistyaningrum, Dwi; Setiyono, Budi

    2017-10-01

    Moving object tracking in a video is a method used to detect and analyze changes that occur in an object that being observed. Visual quality and the precision of the tracked target are highly wished in modern tracking system. The fact that the tracked object does not always seem clear causes the tracking result less precise. The reasons are low quality video, system noise, small object, and other factors. In order to improve the precision of the tracked object especially for small object, we propose a two step solution that integrates a super-resolution technique into tracking approach. First step is super-resolution imaging applied into frame sequences. This step was done by cropping the frame in several frame or all of frame. Second step is tracking the result of super-resolution images. Super-resolution image is a technique to obtain high-resolution images from low-resolution images. In this research single frame super-resolution technique is proposed for tracking approach. Single frame super-resolution was a kind of super-resolution that it has the advantage of fast computation time. The method used for tracking is Camshift. The advantages of Camshift was simple calculation based on HSV color that use its histogram for some condition and color of the object varies. The computational complexity and large memory requirements required for the implementation of super-resolution and tracking were reduced and the precision of the tracked target was good. Experiment showed that integrate a super-resolution imaging into tracking technique can track the object precisely with various background, shape changes of the object, and in a good light conditions.

  11. Trade studies of plasma elongation for next-step tokamaks

    International Nuclear Information System (INIS)

    Galambos, J.D.; Strickler, D.J.; Peng, Y.K.M.; Reid, R.L.

    1988-09-01

    The effect of elongation on minimum-cost devices is investigated for elongations ranging from 2 to 3. The analysis, carried out with the TETRA tokamak systems code, includes the effects of elongation on both physics (plasma beta limit) and engineering (poloidal field coil currents) issues. When ignition is required, the minimum cost occurs for elongations from 2.3 to 2.9, depending on the plasma energy confinement scaling used. Scalings that include favorable plasma current dependence and/or degradation with fusion power tend to have minimum cost at higher elongation (2.5-2.9); scalings that depend primarily on size result in lower elongation (/approximately/2.3) for minimum cost. For design concepts that include steady-state current-driven operation, minimum cost occurs at an elongation of 2.3. 12 refs., 13 figs

  12. Motion of Knots in DNA Stretched by Elongational Fields

    Science.gov (United States)

    Klotz, Alexander R.; Soh, Beatrice W.; Doyle, Patrick S.

    2018-05-01

    Knots in DNA occur in biological systems, serve as a model system for polymer entanglement, and affect the efficacy of modern genomics technologies. We study the motion of complex knots in DNA by stretching molecules with a divergent electric field that provides an elongational force. We demonstrate that the motion of knots is nonisotropic and driven towards the closest end of the molecule. We show for the first time experimentally that knots can go from a mobile to a jammed state by varying an applied strain rate, and that this jamming is reversible. We measure the mobility of knots as a function of strain rate, demonstrating the conditions under which knots can be driven towards the ends of the molecule and untied.

  13. Impressive Super Phenix

    International Nuclear Information System (INIS)

    Olds, F.C.

    1979-01-01

    The 1200-MWe fast breeder reactor, Super Phenix at Creys-Malville, is scheduled for commercial operation in 1983. This is the world's first near-commercial-sized fast breeder. As a near-commercial-sized unit, it represents essentially the technology and hardware of the first fully commercial follow-on units. In its size, its components, its design, the technology it represents, and its project schedule, it is impressive. As of May 1979, the Super Phenix nuclear steam boiler in the Creys-Malville plant bore an estimated cost of $700 million, without fuel. The total cost of the Creys-Malville plant now is estimated at about $1.4 billion. This is about twice the cost of a comparable standardized PWR being built in France today. However, it should be borne in mind that Creys-Malville carries the high cost of a first-of-the-line prototype, and that France's PWRs are standardized, second-generation units. Electricity from Creys-Malville is estimated to cost a little more than electricity would cost from a coal-fired plant complete with flue gas scrubbing

  14. A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts.

    Science.gov (United States)

    Fox, Hannah L; Dembowski, Jill A; DeLuca, Neal A

    2017-06-13

    Herpes simplex virus 1 (HSV-1) genes are transcribed by cellular RNA polymerase II (RNA Pol II). While four viral immediate early proteins (ICP4, ICP0, ICP27, and ICP22) function in some capacity in viral transcription, the mechanism by which ICP22 functions remains unclear. We observed that the FACT complex (comprised of SSRP1 and Spt16) was relocalized in infected cells as a function of ICP22. ICP22 was also required for the association of FACT and the transcription elongation factors SPT5 and SPT6 with viral genomes. We further demonstrated that the FACT complex interacts with ICP22 throughout infection. We therefore hypothesized that ICP22 recruits cellular transcription elongation factors to viral genomes for efficient transcription elongation of viral genes. We reevaluated the phenotype of an ICP22 mutant virus by determining the abundance of all viral mRNAs throughout infection by transcriptome sequencing (RNA-seq). The accumulation of almost all viral mRNAs late in infection was reduced compared to the wild type, regardless of kinetic class. Using chromatin immunoprecipitation sequencing (ChIP-seq), we mapped the location of RNA Pol II on viral genes and found that RNA Pol II levels on the bodies of viral genes were reduced in the ICP22 mutant compared to wild-type virus. In contrast, the association of RNA Pol II with transcription start sites in the mutant was not reduced. Taken together, our results indicate that ICP22 plays a role in recruiting elongation factors like the FACT complex to the HSV-1 genome to allow for efficient viral transcription elongation late in viral infection and ultimately infectious virion production. IMPORTANCE HSV-1 interacts with many cellular proteins throughout productive infection. Here, we demonstrate the interaction of a viral protein, ICP22, with a subset of cellular proteins known to be involved in transcription elongation. We determined that ICP22 is required to recruit the FACT complex and other transcription

  15. Melting in super-earths.

    Science.gov (United States)

    Stixrude, Lars

    2014-04-28

    We examine the possible extent of melting in rock-iron super-earths, focusing on those in the habitable zone. We consider the energetics of accretion and core formation, the timescale of cooling and its dependence on viscosity and partial melting, thermal regulation via the temperature dependence of viscosity, and the melting curves of rock and iron components at the ultra-high pressures characteristic of super-earths. We find that the efficiency of kinetic energy deposition during accretion increases with planetary mass; considering the likely role of giant impacts and core formation, we find that super-earths probably complete their accretionary phase in an entirely molten state. Considerations of thermal regulation lead us to propose model temperature profiles of super-earths that are controlled by silicate melting. We estimate melting curves of iron and rock components up to the extreme pressures characteristic of super-earth interiors based on existing experimental and ab initio results and scaling laws. We construct super-earth thermal models by solving the equations of mass conservation and hydrostatic equilibrium, together with equations of state of rock and iron components. We set the potential temperature at the core-mantle boundary and at the surface to the local silicate melting temperature. We find that ancient (∼4 Gyr) super-earths may be partially molten at the top and bottom of their mantles, and that mantle convection is sufficiently vigorous to sustain dynamo action over the whole range of super-earth masses.

  16. Ardnamurchan 3D cone-sheet architecture explained by a single elongate magma chamber.

    Science.gov (United States)

    Burchardt, Steffi; Troll, Valentin R; Mathieu, Lucie; Emeleus, Henry C; Donaldson, Colin H

    2013-10-08

    The Palaeogene Ardnamurchan central igneous complex, NW Scotland, was a defining place for the development of the classic concepts of cone-sheet and ring-dyke emplacement and has thus fundamentally influenced our thinking on subvolcanic structures. We have used the available structural information on Ardnamurchan to project the underlying three-dimensional (3D) cone-sheet structure. Here we show that a single elongate magma chamber likely acted as the source of the cone-sheet swarm(s) instead of the traditionally accepted model of three successive centres. This proposal is supported by the ridge-like morphology of the Ardnamurchan volcano and is consistent with the depth and elongation of the gravity anomaly underlying the peninsula. Our model challenges the traditional model of cone-sheet emplacement at Ardnamurchan that involves successive but independent centres in favour of a more dynamical one that involves a single, but elongate and progressively evolving magma chamber system.

  17. Super-Memorizers Are Not Super-Recognizers.

    Directory of Open Access Journals (Sweden)

    Meike Ramon

    Full Text Available Humans have a natural expertise in recognizing faces. However, the nature of the interaction between this critical visual biological skill and memory is yet unclear. Here, we had the unique opportunity to test two individuals who have had exceptional success in the World Memory Championships, including several world records in face-name association memory. We designed a range of face processing tasks to determine whether superior/expert face memory skills are associated with distinctive perceptual strategies for processing faces. Superior memorizers excelled at tasks involving associative face-name learning. Nevertheless, they were as impaired as controls in tasks probing the efficiency of the face system: face inversion and the other-race effect. Super memorizers did not show increased hippocampal volumes, and exhibited optimal generic eye movement strategies when they performed complex multi-item face-name associations. Our data show that the visual computations of the face system are not malleable and are robust to acquired expertise involving extensive training of associative memory.

  18. Super-Memorizers Are Not Super-Recognizers.

    Science.gov (United States)

    Ramon, Meike; Miellet, Sebastien; Dzieciol, Anna M; Konrad, Boris Nikolai; Dresler, Martin; Caldara, Roberto

    2016-01-01

    Humans have a natural expertise in recognizing faces. However, the nature of the interaction between this critical visual biological skill and memory is yet unclear. Here, we had the unique opportunity to test two individuals who have had exceptional success in the World Memory Championships, including several world records in face-name association memory. We designed a range of face processing tasks to determine whether superior/expert face memory skills are associated with distinctive perceptual strategies for processing faces. Superior memorizers excelled at tasks involving associative face-name learning. Nevertheless, they were as impaired as controls in tasks probing the efficiency of the face system: face inversion and the other-race effect. Super memorizers did not show increased hippocampal volumes, and exhibited optimal generic eye movement strategies when they performed complex multi-item face-name associations. Our data show that the visual computations of the face system are not malleable and are robust to acquired expertise involving extensive training of associative memory.

  19. Superconducting super collider

    International Nuclear Information System (INIS)

    Limon, P.J.

    1987-01-01

    The Superconducting Super Collider is to be a 20 TeV per beam proton-proton accelerator and collider. Physically the SCC will be 52 miles in circumference and slightly oval in shape. The use of superconducting magnets instead of conventional cuts the circumference from 180 miles to the 52 miles. The operating cost of the SCC per year is estimated to be about $200-250 million. A detailed cost estimate of the project is roughly $3 billion in 1986 dollars. For the big collider ring, the technical cost are dominated by the magnet system. That is why one must focus on the cost and design of the magnets. Presently, the process of site selection is underway. The major R and D efforts concern superconducting dipoles. The magnets use niobium-titanium as a conductor stabilized in a copper matrix. 10 figures

  20. Super insulating aerogel glazing

    DEFF Research Database (Denmark)

    Schultz, Jørgen Munthe; Jensen, Karsten Ingerslev; Kristiansen, Finn Harken

    2004-01-01

    form the weakest part of the thermal envelope with respect to heat loss coefficient, but on the other hand also play an important role for passive solar energy utilisation. For window orientations other than south, the net energy balance will be close to or below zero. However, the properties......Monolithic silica aerogel offers the possibility of combining super insulation and high solar energy transmittance, which has been the background for a previous and a current EU project on research and development of monolithic silica aerogel as transparent insulation in windows. Generally, windows...... of aerogel glazing will allow for a positive net energy gain even for north facing vertical windows in a Danish climate during the heating season. This means that high quality daylight can be obtained even with additional energy gain. On behalf of the partners of the two EU projects, results related...

  1. The Super DREAM Project

    Energy Technology Data Exchange (ETDEWEB)

    Wigmans, Richard [Texas Tech Univ., Lubbock, TX (United States)

    2017-09-25

    Despite the fact that DOE provided only a fraction of the requested funds, the goals we defined in the proposal on which award ER41783 was based were essentially all met. This was partially due to the fact that other funding agencies, which supported our collaborators (especially from Italy and Korea) contributed as well, and partially due to the effective solutions that were developed to compensate for the fact that the detector we had proposed to build had to be scaled down. The performance of the SuperDREAM calorimeter is better than anything that has been built or proposed so far. This has of course not gone unnoticed in the scientific community. Scientists who are preparing experiments for the proposed new generation of particle accelerators (FCCee, CPEC,..) are all very seriously considering the technology developed in this project. Several new collaborations have formed which aim to adapt the dual-readout calorimeter principles to the demands of a 4 environment. Preliminary measurements using silicon photomultipliers as light sensors have already been carried out. This type of readout would make it possible to operate this detector in a magnetic field, and it would also allow for a longitudinal segmentation into electromagnetic and hadronic sections, if so desired. In addition, SiPM readout would eliminate the need for “forests” of fibers sticking out of the rear end of the calorimeter (Figure 1), and obtain an arbitrary fine lateral segmentation, which might be very important for recognizing electrons inside jets. The improvements in our understanding of the fundamental structure of matter and the forces that govern its behavior have always hinged on the availability of detectors that make it possible to explore the possibilities of new, more powerful particle accelerators to the fullest extent. We believe that the SuperDREAM project has created a quantum leap in detector technology, which may turn out to be crucially important for future discoveries in

  2. Super Dielectric Materials

    Directory of Open Access Journals (Sweden)

    Samuel Fromille

    2014-12-01

    Full Text Available Evidence is provided here that a class of materials with dielectric constants greater than 105 at low frequency (<10−2 Hz, herein called super dielectric materials (SDM, can be generated readily from common, inexpensive materials. Specifically it is demonstrated that high surface area alumina powders, loaded to the incipient wetness point with a solution of boric acid dissolved in water, have dielectric constants, near 0 Hz, greater than 4 × 108 in all cases, a remarkable increase over the best dielectric constants previously measured for energy storage capabilities, ca. 1 × 104. It is postulated that any porous, electrically insulating material (e.g., high surface area powders of silica, titania, etc., filled with a liquid containing a high concentration of ionic species will potentially be an SDM. Capacitors created with the first generated SDM dielectrics (alumina with boric acid solution, herein called New Paradigm Super (NPS capacitors display typical electrostatic capacitive behavior, such as increasing capacitance with decreasing thickness, and can be cycled, but are limited to a maximum effective operating voltage of about 0.8 V. A simple theory is presented: Water containing relatively high concentrations of dissolved ions saturates all, or virtually all, the pores (average diameter 500 Å of the alumina. In an applied field the positive ionic species migrate to the cathode end, and the negative ions to the anode end of each drop. This creates giant dipoles with high charge, hence leading to high dielectric constant behavior. At about 0.8 V, water begins to break down, creating enough ionic species to “short” the individual water droplets. Potentially NPS capacitor stacks can surpass “supercapacitors” in volumetric energy density.

  3. Using dynamic input allocation for elongation control at FTU

    International Nuclear Information System (INIS)

    Boncagni, L.; Galeani, S.; Granucci, G.; Varano, G.; Vitale, V.; Zaccarian, L.

    2010-01-01

    In this paper we exploit the dynamic allocation scheme for input redundant control systems proposed in to achieve elongation control on FTU (Frascati Tokamak Upgrade). The scheme first serves as a means for regulating the current in the F coils. Then, due to the quasi-static relationship between the plasma elongation and the F coils current, elongation control is achieved by suitably generalizing the allocation scheme. Both simulation and experimental results are reported.

  4. Ubiquitylation and degradation of elongating RNA polymerase II

    DEFF Research Database (Denmark)

    Wilson, Marcus D; Harreman, Michelle; Svejstrup, Jesper Q

    2013-01-01

    During its journey across a gene, RNA polymerase II has to contend with a number of obstacles to its progression, including nucleosomes, DNA-binding proteins, DNA damage, and sequences that are intrinsically difficult to transcribe. Not surprisingly, a large number of elongation factors have....... In this review, we describe the mechanisms and factors responsible for the last resort mechanism of transcriptional elongation. This article is part of a Special Issue entitled: RNA polymerase II Transcript Elongation....

  5. Grassmann, super-Kac-Moody and super-derivation algebras

    International Nuclear Information System (INIS)

    Frappat, L.; Ragoucy, E.; Sorba, P.

    1989-05-01

    We study the cyclic cocycles of degree one on the Grassmann algebra and on the super-circle with N supersymmetries (i.e. the tensor product of the algebra of functions on the circle times a Grassmann algebra with N generators). They are related to central extensions of graded loop algebras (i.e. super-Kac-Moody algebras). The corresponding algebras of super-derivations have to be compatible with the cocycle characterizing the extension; we give a general method for determining these algebras and examine in particular the cases N = 1,2,3. We also discuss their relations with the Ademollo et al. algebras, and examine the possibility of defining new kinds of super-conformal algebras, which, for N > 1, generalize the N = 1 Ramond-Neveu-Schwarz algebra

  6. Electrically tuned super-capacitors

    OpenAIRE

    Chowdhury, Tazima S.; Grebel, Haim

    2015-01-01

    Fast charging and discharging of large amounts of electrical energy make super-capacitors ideal for short-term energy storage [1-5]. In its simplest form, the super-capacitor is an electrolytic capacitor made of an anode and a cathode immersed in an electrolyte. As for an ordinary capacitor, minimizing the charge separation distance and increasing the electrode area increase capacitance. In super-capacitors, charge separation is of nano-meter scale at each of the electrode interface (the Helm...

  7. The Super-Kamiokande detector

    International Nuclear Information System (INIS)

    Fukuda, S.; Fukuda, Y.; Hayakawa, T.; Ichihara, E.; Ishitsuka, M.; Itow, Y.; Kajita, T.; Kameda, J.; Kaneyuki, K.; Kasuga, S.; Kobayashi, K.; Kobayashi, Y.; Koshio, Y.; Miura, M.; Moriyama, S.; Nakahata, M.; Nakayama, S.; Namba, T.; Obayashi, Y.; Okada, A.; Oketa, M.; Okumura, K.; Oyabu, T.; Sakurai, N.; Shiozawa, M.; Suzuki, Y.; Takeuchi, Y.; Toshito, T.; Totsuka, Y.; Yamada, S.; Desai, S.; Earl, M.; Hong, J.T.; Kearns, E.; Masuzawa, M.; Messier, M.D.; Stone, J.L.; Sulak, L.R.; Walter, C.W.; Wang, W.; Scholberg, K.; Barszczak, T.; Casper, D.; Liu, D.W.; Gajewski, W.; Halverson, P.G.; Hsu, J.; Kropp, W.R.; Mine, S.; Price, L.R.; Reines, F.; Smy, M.; Sobel, H.W.; Vagins, M.R.; Ganezer, K.S.; Keig, W.E.; Ellsworth, R.W.; Tasaka, S.; Flanagan, J.W.; Kibayashi, A.; Learned, J.G.; Matsuno, S.; Stenger, V.J.; Hayato, Y.; Ishii, T.; Ichikawa, A.; Kanzaki, J.; Kobayashi, T.; Maruyama, T.; Nakamura, K.; Oyama, Y.; Sakai, A.; Sakuda, M.; Sasaki, O.; Echigo, S.; Iwashita, T.; Kohama, M.; Suzuki, A.T.; Hasegawa, M.; Inagaki, T.; Kato, I.; Maesaka, H.; Nakaya, T.; Nishikawa, K.; Yamamoto, S.; Haines, T.J.; Kim, B.K.; Sanford, R.; Svoboda, R.; Blaufuss, E.; Chen, M.L.; Conner, Z.; Goodman, J.A.; Guillian, E.; Sullivan, G.W.; Turcan, D.; Habig, A.; Ackerman, M.; Goebel, F.; Hill, J.; Jung, C.K.; Kato, T.; Kerr, D.; Malek, M.; Martens, K.; Mauger, C.; McGrew, C.; Sharkey, E.; Viren, B.; Yanagisawa, C.; Doki, W.; Inaba, S.; Ito, K.; Kirisawa, M.; Kitaguchi, M.; Mitsuda, C.; Miyano, K.; Saji, C.; Takahata, M.; Takahashi, M.; Higuchi, K.; Kajiyama, Y.; Kusano, A.; Nagashima, Y.; Nitta, K.; Takita, M.; Yamaguchi, T.; Yoshida, M.; Kim, H.I.; Kim, S.B.; Yoo, J.; Okazawa, H.; Etoh, M.; Fujita, K.; Gando, Y.; Hasegawa, A.; Hasegawa, T.; Hatakeyama, S.; Inoue, K.; Ishihara, K.; Iwamoto, T.; Koga, M.; Nishiyama, I.; Ogawa, H.; Shirai, J.; Suzuki, A.; Takayama, T.; Tsushima, F.; Koshiba, M.; Ichikawa, Y.; Hashimoto, T.; Hatakeyama, Y.; Koike, M.; Horiuchi, T.; Nemoto, M.; Nishijima, K.; Takeda, H.; Fujiyasu, H.; Futagami, T.; Ishino, H.; Kanaya, Y.; Morii, M.; Nishihama, H.; Nishimura, H.; Suzuki, T.; Watanabe, Y.; Kielczewska, D.; Golebiewska, U.; Berns, H.G.; Boyd, S.B.; Doyle, R.A.; George, J.S.; Stachyra, A.L.; Wai, L.L.; Wilkes, R.J.; Young, K.K.; Kobayashi, H.

    2003-01-01

    Super-Kamiokande is the world's largest water Cherenkov detector, with net mass 50,000 tons. During the period April, 1996 to July, 2001, Super-Kamiokande I collected 1678 live-days of data, observing neutrinos from the Sun, Earth's atmosphere, and the K2K long-baseline neutrino beam with high efficiency. These data provided crucial information for our current understanding of neutrino oscillations, as well as setting stringent limits on nucleon decay. In this paper, we describe the detector in detail, including its site, configuration, data acquisition equipment, online and offline software, and calibration systems which were used during Super-Kamiokande I

  8. Abscisic Acid Stimulates Elongation of Excised Pea Root Tips

    Science.gov (United States)

    Gaither, Douglas H.; Lutz, Donald H.; Forrence, Leonard E.

    1975-01-01

    Excised Pisum sativum L. root tips were incubated in a pH 5.2 sucrose medium containing abscisic acid. Elongation growth was inhibited by 100 μm abscisic acid. However, decreasing the abscisic acid concentration caused stimulation of elongation, the maximum response (25% to 30%) occurring at 1 μm abscisic acid. Prior to two hours, stimulation of elongation by 1 μm abscisic acid was not detectable. Increased elongation did not occur in abscisic acid-treated root tips of Lens culinaris L., Phaseolus vulgaris L., or Zea mays L. PMID:16659198

  9. Bilateral elongated styloid process: Its anatomical, embryological and clinical implications

    OpenAIRE

    Bagoji Ishwar B, Hadimani Gavishiddappa A, Patil Balasaheb G, Bannur Balappa M,Ambadasu B

    2013-01-01

    The styloid process is a slender, elongated, cylindrical bony projection from temporal bone. It normally varies in length from 2 cm to 3 cm. During a routine demonstration of skull for MBBS students we found the bilateral elongated styloid process in dry human skull. The length of elongation measured on the right and left side was 6.0 & 5.9 cms respectively. Such abnormal elongation of the styloid process may cause compression on a number of vital vessels and nerves related to it, producing i...

  10. SuperB Progress Report: Detector

    International Nuclear Information System (INIS)

    Grauges, E.; Donvito, G.; Spinoso, V.; Manghisoni, M.; Re, V.; Traversi, G.; Eigen, G.; Fehlker, D.; Helleve, L.; Cheng, C.; Chivukula, A.; Doll, D.; Echenard, B.; Hitlin, D.; Ongmongkolkul, P.; Porter, F.; Rakitin, A.; Thomas, M.; Zhu, R.; Tatishvili, G.; Andreassen, R.; Fabby, C.; Meadows, B.; Simpson, A.; Sokoloff, M.; Tomko, K.; Fella, A.; Andreotti, M.; Baldini, W.; Calabrese, R.; Carassiti, V.; Cibinetto, G.; Cotta Ramusino, A.; Gianoli, A.; Luppi, E.; Munerato, M.; Santoro, V.; Tomassetti, L.; Stoker, D.; Bezshyyko, O.; Dolinska, G.; Arnaud, N.; Beigbeder, C.; Bogard, F.; Breton, D.; Burmistrov, L.; Charlet, D.; Maalmi, J.; Perez Perez, L.; Puill, V.; Stocchi, A.; Tocut, V.; Wallon, S.; Wormser, G.; Brown, D.

    2012-01-01

    This report describes the present status of the detector design for SuperB. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  11. SuperB Progress Report: Detector

    Energy Technology Data Exchange (ETDEWEB)

    Grauges, E.; /Barcelona U., ECM; Donvito, G.; Spinoso, V.; /INFN, Bari /Bari U.; Manghisoni, M.; Re, V.; Traversi, G.; /INFN, Pavia /Bergamo U., Ingengneria Dept.; Eigen, G.; Fehlker, D.; Helleve, L.; /Bergen U.; Carbone, A.; Di Sipio, R.; Gabrielli, A.; Galli, D.; Giorgi, F.; Marconi, U.; Perazzini, S.; Sbarra, C.; Vagnoni, V.; Valentinetti, S.; Villa, M.; Zoccoli, A.; /INFN, Bologna /Bologna U. /Caltech /Carleton U. /Cincinnati U. /INFN, CNAF /INFN, Ferrara /Ferrara U. /UC, Irvine /Taras Shevchenko U. /Orsay, LAL /LBL, Berkeley /UC, Berkeley /Frascati /INFN, Legnaro /Orsay, IPN /Maryland U. /McGill U. /INFN, Milan /Milan U. /INFN, Naples /Naples U. /Novosibirsk, IYF /INFN, Padua /Padua U. /INFN, Pavia /Pavia U. /INFN, Perugia /Perugia U. /INFN, Perugia /Caltech /INFN, Pisa /Pisa U. /Pisa, Scuola Normale Superiore /PNL, Richland /Queen Mary, U. of London /Rutherford /INFN, Rome /Rome U. /INFN, Rome2 /Rome U.,Tor Vergata /INFN, Rome3 /Rome III U. /SLAC /Tel Aviv U. /INFN, Turin /Turin U. /INFN, Padua /Trento U. /INFN, Trieste /Trieste U. /TRIUMF /British Columbia U. /Montreal U. /Victoria U.

    2012-02-14

    This report describes the present status of the detector design for SuperB. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  12. SuperB Progress Reports Accelerator

    CERN Document Server

    Biagini, Maria Enrica; Boscolo, M; Buonomo, B; Demma, T; Drago, A; Esposito, M; Guiducci, S; Mazzitelli, G; Pellegrino, L; Preger, M A; Raimondi, P; Ricci, R; Rotundo, U; Sanelli, C; Serio, M; Stella, A; Tomassini, S; Zobov, M; Bertsche, K; Brachman, A; Cai, Y; Chao, A; Chesnut, R; Donald, M.H; Field, C; Fisher, A; Kharakh, D; Krasnykh, A; Moffeit, K; Nosochkov, Y; Pivi, M; Seeman, J; Sullivan, M.K; Weathersby, S; Weidemann, A; Weisend, J; Wienands, U; Wittmer, W; Woods, M; Yocky, G; Bogomiagkov, A; Koop, I; Levichev, E; Nikitin, S; Okunev, I; Piminov, P; Sinyatkin, S; Shatilov, D; Vobly, P; Bosi, F; Liuzzo, S; Paoloni, E; Bonis, J; Chehab, R; Le Meur, G; Lepercq, P; Letellier-Cohen, F; Mercier, B; Poirier, F; Prevost, C; Rimbault, C; Touze, F; Variola, A; Bolzon, B; Brunetti, L; Jeremie, A; Baylac, M; Bourrion, O; De Conto, J M; Gomez, Y; Meot, F; Monseu, N; Tourres, D; Vescovi, C; Chanci, A; Napoly, O; Barber, D P; Bettoni, S; Quatraro, D

    2010-01-01

    This report details the present status of the Accelerator design for the SuperB Project. It is one of four separate progress reports that, taken collectively, describe progress made on the SuperB Project since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008.

  13. Super-multiplex vibrational imaging

    Science.gov (United States)

    Wei, Lu; Chen, Zhixing; Shi, Lixue; Long, Rong; Anzalone, Andrew V.; Zhang, Luyuan; Hu, Fanghao; Yuste, Rafael; Cornish, Virginia W.; Min, Wei

    2017-04-01

    potential of this 24-colour (super-multiplex) optical imaging approach for elucidating intricate interactions in complex biological systems.

  14. A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts

    Directory of Open Access Journals (Sweden)

    Hannah L. Fox

    2017-06-01

    Full Text Available Herpes simplex virus 1 (HSV-1 genes are transcribed by cellular RNA polymerase II (RNA Pol II. While four viral immediate early proteins (ICP4, ICP0, ICP27, and ICP22 function in some capacity in viral transcription, the mechanism by which ICP22 functions remains unclear. We observed that the FACT complex (comprised of SSRP1 and Spt16 was relocalized in infected cells as a function of ICP22. ICP22 was also required for the association of FACT and the transcription elongation factors SPT5 and SPT6 with viral genomes. We further demonstrated that the FACT complex interacts with ICP22 throughout infection. We therefore hypothesized that ICP22 recruits cellular transcription elongation factors to viral genomes for efficient transcription elongation of viral genes. We reevaluated the phenotype of an ICP22 mutant virus by determining the abundance of all viral mRNAs throughout infection by transcriptome sequencing (RNA-seq. The accumulation of almost all viral mRNAs late in infection was reduced compared to the wild type, regardless of kinetic class. Using chromatin immunoprecipitation sequencing (ChIP-seq, we mapped the location of RNA Pol II on viral genes and found that RNA Pol II levels on the bodies of viral genes were reduced in the ICP22 mutant compared to wild-type virus. In contrast, the association of RNA Pol II with transcription start sites in the mutant was not reduced. Taken together, our results indicate that ICP22 plays a role in recruiting elongation factors like the FACT complex to the HSV-1 genome to allow for efficient viral transcription elongation late in viral infection and ultimately infectious virion production.

  15. Elongated Styloid Process and Cervical Spondylosis

    Directory of Open Access Journals (Sweden)

    Zeliha Unlu MD

    2008-01-01

    Full Text Available Background Dysphagia, is a significant sign of many different lesions in upper digestive system especially in proximal esophagus. Tumors, gastroesophageal reflux, achalasia and extrinsic compressions are the most common causes that may lead to dysphagia in geriatric population. Cervical osteophyte induced dysphagia, is one of the uncommon reasons of dysphagia, therefore other causes of dysphagia must be excluded to establish the exact diagnosis. Eagle syndrome is one of the considerable reason which may lead to misdiagnosis in patients with cervical osteophytes. In this case report, we represent four patients who had dysphagia due to anteriorly located cervical osteophytes and evaluate the patients with special reference to Eagle syndrome. Material and methods After a detailed anamnesis and ENT examination, cervical plain radiographs in four projections and Towne radiographs were obtained for every patient. After that, magnetic resonance imaging (MRI of cervical spine and barium swallowing studies were performed to evaluate the presence of esophageal compression. Results Eagle syndrome was excluded due to absence of other symptoms and physical signs, eventhough unilateral or bilateral elongation of styloid processes was found in all of the patients. Conclusion Cervical osteophytes induced dysphagia is a rare clinical entity, diagnosis should be done by a careful examination, intensive radiologic evaluation. Moreover, all the other causes like Eagle syndrome should be excluded during the diagnosis of cervical osteophyte induced dysphagia.

  16. Mass composition analysis using elongation rate

    Energy Technology Data Exchange (ETDEWEB)

    Ochilo, Livingstone; Risse, Markus; Yushkov, Alexey [University of Siegen, Siegen (Germany)

    2015-07-01

    The all-particle cosmic ray energy spectrum has been observed to flatten at around 5.2 x 10{sup 18} eV where the spectral index changes from γ = 3.2 to γ = 2.6, a feature called the ''ankle'' of the spectrum. Cosmic rays with energy around the ankle and beyond, known as ultra-high energy cosmic rays (UHECR), have a very low flux and reconstruction of their properties from extensive air shower measurements is subject to uncertainties for instance from hadronic interaction models. Since the year 2004, the Pierre Auger Observatory has recorded a considerable number of UHECR events beyond the ankle. With the greatly improved statistics, the mass composition of the extreme end of the cosmic ray energy spectrum is now being investigated with improved accuracy. The measured composition of UHECR is an important parameter in validating the models used to explain their sources and acceleration mechanisms. In this study, we perform a mass composition analysis using elongation rate (the rate of change of the depth of shower maximum with energy), measured by the fluorescence detector of the Pierre Auger Observatory. The advantage of this approach is a weak dependence of the results on the choice of the hadronic interaction models.

  17. Super boson-fermion correspondence

    International Nuclear Information System (INIS)

    Kac, V.G.; Leur van de, J.W.

    1987-01-01

    Since the pioneering work of Skyrme, the boson-fermion correspondence has been playing an increasingly important role in 2-dimensional quantum field theory. More recently, it has become an important ingredient in the work of the Kyoto school on the KP hierarchy of soliton equations. In the present paper we establish a super boson-fermion correspondence, having in mind its applications to super KP hierarchies

  18. CEP295 interacts with microtubules and is required for centriole elongation.

    Science.gov (United States)

    Chang, Ching-Wen; Hsu, Wen-Bin; Tsai, Jhih-Jie; Tang, Chieh-Ju C; Tang, Tang K

    2016-07-01

    Centriole duplication is a tightly ordered process during which procentrioles are assembled in G1-S and elongate during S and G2. Here, we show that human CEP295 (Drosophila Ana1) is not essential for initial cartwheel assembly, but is required to build distal half centrioles during S and G2. Using super-resolution and immunogold electron microscopy, we demonstrate that CEP295 is recruited to the proximal end of procentrioles in early S phase, when it is also localized at the centriolar microtubule wall that surrounds the human SAS6 cartwheel hub. Interestingly, depletion of CEP295 not only inhibits the recruitments of POC5 and POC1B to the distal half centrioles in G2, resulting in shorter centrioles, it also blocks the post-translational modification of centriolar microtubules (e.g. acetylation and glutamylation). Importantly, our results indicate that CEP295 directly interacts with microtubules, and that excess CEP295 could induce the assembly of overly long centrioles. Furthermore, exogenous expression of the N-terminal domain of CEP295 exerts a dominant-negative effect on centriole elongation. Collectively, these findings suggest that CEP295 is essential for building the distal half centrioles and for post-translational modification of centriolar microtubules. © 2016. Published by The Company of Biologists Ltd.

  19. Super power generators

    International Nuclear Information System (INIS)

    Martin, T.H.; Johnson, D.L.; McDaniel, D.H.

    1977-01-01

    PROTO II, a super power generator, is presently undergoing testing at Sandia Laboratories. It has operated with an 80 ns, 50 ns, 35 ns, and 20 ns positive output pulse high voltage mode and achieved total current rates of rise of 4 x 10 14 A/s. The two sided disk accelerator concept using two diodes has achieved voltages of 1.5 MV and currents of 4.5 MA providing a power exceeding 6 TW in the electron beam and 8 TW in the transmission lines. A new test bed named MITE (Magnetically Insulated Transmission Experiment) was designed and is now being tested. The pulse forming lines are back to back short pulse Blumleins which use untriggered water switching. Output data showing a ten ns half width power pulse peaking above one terrawatt were obtained. MITE is a module being investigated for use in the Electron Beam Fusion Accelerator and will be used to test the effects of short pulses propagating down vacuum transmission lines

  20. Super oil cracking update

    International Nuclear Information System (INIS)

    Mulraney, D.

    1997-01-01

    The conversion of residual fuel oil to usable middle distillates was discussed. The residue conversion processing paths are usually based on separation, carbon rejection, or hydrogen addition principles. Super Oil Cracking (SOC) uses a slurry catalyst system in a new, tubular reactor to achieve high levels of hydrothermal conversion. SOC can upgrade a variety of heavy, high metals residue feedstocks with high yields of middle distillates. The SOC products can also be further treated into feedstocks for FCC or hydrocracking. The SOC process can be incorporated easily into a refinery to obtain incremental residue conversion directly. It can also be integrated with other residue processes, acting as a demetallization and decarbonization step which results in enhanced overall conversion. The relative rate of coke formation and its handling are distinguishing characteristics between residue upgrading technologies. The SOC process operates at higher temperatures that other residue hydrocracking processes resulting in higher rates of thermal decomposition, thus preventing coke formation. SOC process can operate as a stand-alone upgrader or can be integrated with other bottoms processing steps to extend the refiner's range of options for increasing bottoms conversion.3 tabs., 14 figs

  1. Halogenated auxins affect microtubules and root elongation in Lactuca sativa

    Science.gov (United States)

    Zhang, N.; Hasenstein, K. H.

    2000-01-01

    We studied the effect of 4,4,4-trifluoro-3-(indole-3-)butyric acid (TFIBA), a recently described root growth stimulator, and 5,6-dichloro-indole-3-acetic acid (DCIAA) on growth and microtubule (MT) organization in roots of Lactuca sativa L. DCIAA and indole-3-butyric acid (IBA) inhibited root elongation and depolymerized MTs in the cortex of the elongation zone, inhibited the elongation of stele cells, and promoted xylem maturation. Both auxins caused the plane of cell division to shift from anticlinal to periclinal. In contrast, TFIBA (100 micromolar) promoted elongation of primary roots by 40% and stimulated the elongation of lateral roots, even in the presence of IBA, the microtubular inhibitors oryzalin and taxol, or the auxin transport inhibitor naphthylphthalamic acid. However, TFIBA inhibited the formation of lateral root primordia. Immunostaining showed that TFIBA stabilized MTs orientation perpendicular to the root axis, doubled the cortical cell length, but delayed xylem maturation. The data indicate that the auxin-induced inhibition of elongation and swelling of roots results from reoriented phragmoplasts, the destabilization of MTs in elongating cells, and promotion of vessel formation. In contrast, TFIBA induced promotion of root elongation by enhancing cell length, prolonging transverse MT orientation, delaying cell and xylem maturation.

  2. High n ballooning modes in highly elongated tokamaks

    International Nuclear Information System (INIS)

    An, C.H.; Bateman, G.

    1980-02-01

    An analytic study of stability against high n ballooning modes in highly elongated axisymmetric plasmas is presented and compared with computational results. From the equation for the marginal pressure gradient, it is found that the local shear plays an important role on the stability of elongated and shifted plasma, and that high elongation deteriorates the stability by decreasing the stabilizing effects of field line bending and local shear. The net contribution of the local shear to stability decreases with elongation and shift for strongly ballooning modes (eigenfunctions strongly localized near the outer edge of the toroidal flux surfaces) but increases for interchange modes (eigenfunctions more uniform along the flux surfaces). The computational study of high n ballooning modes in a highly elongated plasma reveals that lowering the aspect ratio and broadening the pressure profile enhance the marginal beta for β/sub p/ less than unity but severely reduce the marginal beta for β/sub p/ larger than unity

  3. Nuclear starburst activity induced by elongated bulges in spiral galaxies

    Science.gov (United States)

    Kim, Eunbin; Kim, Sungsoo S.; Choi, Yun-Young; Lee, Gwang-Ho; de Grijs, Richard; Lee, Myung Gyoon; Hwang, Ho Seong

    2018-06-01

    We study the effects of bulge elongation on the star formation activity in the centres of spiral galaxies using the data from the Sloan Digital Sky Survey Data Release 7. We construct a volume-limited sample of face-on spiral galaxies with Mr nuclear starbursts using the fibre specific star formation rates derived from the SDSS spectra. We find a statistically significant correlation between bulge elongation and nuclear starbursts in the sense that the fraction of nuclear starbursts increases with bulge elongation. This correlation is more prominent for fainter and redder galaxies, which exhibit higher ratios of elongated bulges. We find no significant environmental dependence of the correlation between bulge elongation and nuclear starbursts. These results suggest that non-axisymmetric bulges can efficiently feed the gas into the centre of galaxies to trigger nuclear starburst activity.

  4. (R)-β-lysine-modified elongation factor P functions in translation elongation

    DEFF Research Database (Denmark)

    Bullwinkle, Tammy J; Zou, S Betty; Rajkovic, Andrei

    2013-01-01

    Post-translational modification of bacterial elongation factor P (EF-P) with (R)-β-lysine at a conserved lysine residue activates the protein in vivo and increases puromycin reactivity of the ribosome in vitro. The additional hydroxylation of EF-P at the same lysine residue by the YfcM protein has......-(β)-lysyl-EF-P showed 30% increased puromycin reactivity but no differences in dipeptide synthesis rates when compared with the β-lysylated form. Unlike disruption of the other genes required for EF-P modification, deletion of yfcM had no phenotypic consequences in Salmonella. Taken together, our findings indicate...

  5. Super Dielectric Materials.

    Science.gov (United States)

    Fromille, Samuel; Phillips, Jonathan

    2014-12-22

    Evidence is provided here that a class of materials with dielectric constants greater than 10⁵ at low frequency (dielectric materials (SDM), can be generated readily from common, inexpensive materials. Specifically it is demonstrated that high surface area alumina powders, loaded to the incipient wetness point with a solution of boric acid dissolved in water, have dielectric constants, near 0 Hz, greater than 4 × 10⁸ in all cases, a remarkable increase over the best dielectric constants previously measured for energy storage capabilities, ca. 1 × 10⁴. It is postulated that any porous, electrically insulating material (e.g., high surface area powders of silica, titania, etc. ), filled with a liquid containing a high concentration of ionic species will potentially be an SDM. Capacitors created with the first generated SDM dielectrics (alumina with boric acid solution), herein called New Paradigm Super (NPS) capacitors display typical electrostatic capacitive behavior, such as increasing capacitance with decreasing thickness, and can be cycled, but are limited to a maximum effective operating voltage of about 0.8 V. A simple theory is presented: Water containing relatively high concentrations of dissolved ions saturates all, or virtually all, the pores (average diameter 500 Å) of the alumina. In an applied field the positive ionic species migrate to the cathode end, and the negative ions to the anode end of each drop. This creates giant dipoles with high charge, hence leading to high dielectric constant behavior. At about 0.8 V, water begins to break down, creating enough ionic species to "short" the individual water droplets. Potentially NPS capacitor stacks can surpass "supercapacitors" in volumetric energy density.

  6. MreB-Dependent Inhibition of Cell Elongation during the Escape from Competence in Bacillus subtilis.

    Science.gov (United States)

    Mirouze, Nicolas; Ferret, Cécile; Yao, Zhizhong; Chastanet, Arnaud; Carballido-López, Rut

    2015-06-01

    During bacterial exponential growth, the morphogenetic actin-like MreB proteins form membrane-associated assemblies that move processively following trajectories perpendicular to the long axis of the cell. Such MreB structures are thought to scaffold and restrict the movement of peptidoglycan synthesizing machineries, thereby coordinating sidewall elongation. In Bacillus subtilis, this function is performed by the redundant action of three MreB isoforms, namely MreB, Mbl and MreBH. mreB and mbl are highly transcribed from vegetative promoters. We have found that their expression is maximal at the end of exponential phase, and rapidly decreases to a low basal level upon entering stationary phase. However, in cells developing genetic competence, a stationary phase physiological adaptation, expression of mreB was specifically reactivated by the central competence regulator ComK. In competent cells, MreB was found in complex with several competence proteins by in vitro pull-down assays. In addition, it co-localized with the polar clusters formed by the late competence peripheral protein ComGA, in a ComGA-dependent manner. ComGA has been shown to be essential for the inhibition of cell elongation characteristic of cells escaping the competence state. We show here that the pathway controlling this elongation inhibition also involves MreB. Our findings suggest that ComGA sequesters MreB to prevent cell elongation and therefore the escape from competence.

  7. MreB-Dependent Inhibition of Cell Elongation during the Escape from Competence in Bacillus subtilis.

    Directory of Open Access Journals (Sweden)

    Nicolas Mirouze

    2015-06-01

    Full Text Available During bacterial exponential growth, the morphogenetic actin-like MreB proteins form membrane-associated assemblies that move processively following trajectories perpendicular to the long axis of the cell. Such MreB structures are thought to scaffold and restrict the movement of peptidoglycan synthesizing machineries, thereby coordinating sidewall elongation. In Bacillus subtilis, this function is performed by the redundant action of three MreB isoforms, namely MreB, Mbl and MreBH. mreB and mbl are highly transcribed from vegetative promoters. We have found that their expression is maximal at the end of exponential phase, and rapidly decreases to a low basal level upon entering stationary phase. However, in cells developing genetic competence, a stationary phase physiological adaptation, expression of mreB was specifically reactivated by the central competence regulator ComK. In competent cells, MreB was found in complex with several competence proteins by in vitro pull-down assays. In addition, it co-localized with the polar clusters formed by the late competence peripheral protein ComGA, in a ComGA-dependent manner. ComGA has been shown to be essential for the inhibition of cell elongation characteristic of cells escaping the competence state. We show here that the pathway controlling this elongation inhibition also involves MreB. Our findings suggest that ComGA sequesters MreB to prevent cell elongation and therefore the escape from competence.

  8. Quantization of super Teichmueller spaces

    International Nuclear Information System (INIS)

    Aghaei, Nezhla

    2016-08-01

    The quantization of the Teichmueller spaces of Riemann surfaces has found important applications to conformal field theory and N=2 supersymmetric gauge theories. We construct a quantization of the Teichmueller spaces of super Riemann surfaces, using coordinates associated to the ideal triangulations of super Riemann surfaces. A new feature is the non-trivial dependence on the choice of a spin structure which can be encoded combinatorially in a certain refinement of the ideal triangulation. We construct a projective unitary representation of the groupoid of changes of refined ideal triangulations. Therefore, we demonstrate that the dependence of the resulting quantum theory on the choice of a triangulation is inessential. In the quantum Teichmueller theory, it was observed that the key object defining the Teichmueller theory has a close relation to the representation theory of the Borel half of U q (sl(2)). In our research we observed that the role of U q (sl(2)) is taken by quantum superalgebra U q (osp(1 vertical stroke 2)). A Borel half of U q (osp(1 vertical stroke 2)) is the super quantum plane. The canonical element of the Heisenberg double of the quantum super plane is evaluated in certain infinite dimensional representations on L 2 (R) x C 1 vertical stroke 1 and compared to the flip operator from the Teichmueller theory of super Riemann surfaces.

  9. ATFL elongation after Brostrom procedure: a biomechanical investigation.

    Science.gov (United States)

    Kirk, Kevin L; Campbell, John T; Guyton, Gregory P; Parks, Brent G; Schon, Lew C

    2008-11-01

    Elongation of ligaments during early mobilization after reconstruction may be associated with decreased stability. We evaluated elongation of the anterior talofibular ligament (ATFL) before and after lateral ligament reconstruction within a physiologic range of motion with protected and unprotected, isolated dorsiflexion/plantarflexion range of motion. Six fresh frozen cadaver legs were used with the ATFL meticulously dissected. A differential variable reluctance transducer (DVRT) was spaced to span the course of the ATFL using consistent placement points based on previous reports. Elongation was measured in a load frame with protected motion of 30 degrees plantarflexion and 10 degrees dorsiflexion for the intact and sectioned ATFL and for the repaired specimen with and without protected motion. The proximal DVRT anchor point was detached for sectioning and repair of the ATFL and replaced at the same position. Testing was 1000 cycles at 1 Hz for the repaired protected specimen and 10 cycles at 1 Hz for all other stages. Initial elongation in the unprotected, repaired group was significantly higher than initial elongation in the intact (p ankle after lateral ankle ligament reconstruction was not associated with elongation of the ATFL. The ATFL elongated significantly by comparison without protected dorsiflexion/plantarflexion. The study provides biomechanical support for the safety of early protected dorsiflexion/plantarflexion range of motion after Broström reconstruction.

  10. Super-resolution fluorescence microscopy by stepwise optical saturation

    Science.gov (United States)

    Zhang, Yide; Nallathamby, Prakash D.; Vigil, Genevieve D.; Khan, Aamir A.; Mason, Devon E.; Boerckel, Joel D.; Roeder, Ryan K.; Howard, Scott S.

    2018-01-01

    Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the super-resolution microscopy is not feasible in many applications. In this paper, we propose and demonstrate a saturation-based super-resolution fluorescence microscopy technique that can be easily implemented and requires neither additional hardware nor complex post-processing. The method is based on the principle of stepwise optical saturation (SOS), where M steps of raw fluorescence images are linearly combined to generate an image with a M-fold increase in resolution compared with conventional diffraction-limited images. For example, linearly combining (scaling and subtracting) two images obtained at regular powers extends the resolution by a factor of 1.4 beyond the diffraction limit. The resolution improvement in SOS microscopy is theoretically infinite but practically is limited by the signal-to-noise ratio. We perform simulations and experimentally demonstrate super-resolution microscopy with both one-photon (confocal) and multiphoton excitation fluorescence. We show that with the multiphoton modality, the SOS microscopy can provide super-resolution imaging deep in scattering samples. PMID:29675306

  11. Scattering phaseshift formulas for mesons and baryons in elongated boxes

    Science.gov (United States)

    Lee, Frank X.; Alexandru, Andrei

    2018-03-01

    We derive Lüscher phaseshift formulas for two-particle states in boxes elongated in one of the dimensions. Such boxes offer a cost-effective way of varying the relative momentum of the particles. Boosted states in the elongated direction, which allow wider access to energies, are also considered. The formulas for the various scenarios (moving and zero-momentum states in cubic and elongated boxes) are compared and relations between them are clarified. The results are applicable to a wide set of meson-meson and meson-baryon elastic scattering processes, with the two-particle system having equal or unequal masses.

  12. Siting the superconducting super collider

    International Nuclear Information System (INIS)

    Price, R.; Rooney, R.C.

    1988-01-01

    At the request of the Department of Energy, the National Academy of Sciences and the National Academy of Engineering established the Super Collider Site Evaluation Committee to evaluate the suitability of proposed sites for the Superconducting Super Collider. Thirty-six proposals were examined by the committee. Using the set of criteria announced by DOE in its Invitation for Site Proposals, the committee identified eight sites that merited inclusion on a ''best qualified list.'' The list represents the best collective judgment of 21 individuals, carefully chosen for their expertise and impartiality, after a detailed assessment of the proposals using 19 technical subcriteria and DOE's life cycle cost estimates. The sites, in alphabetical order, are: Arizona/Maricopa; Colorado; Illinois; Michigan/Stockbridge; New York/Rochester; North Carolina; Tennessee; and Texas/Dallas-Fort Worth. The evaluation of these sites and the Superconducting Super Collider are discussed in this book

  13. Quantisation of super Teichmueller theory

    International Nuclear Information System (INIS)

    Aghaei, Nezhla; Hamburg Univ.; Pawelkiewicz, Michal; Techner, Joerg

    2015-12-01

    We construct a quantisation of the Teichmueller spaces of super Riemann surfaces using coordinates associated to ideal triangulations of super Riemann surfaces. A new feature is the non-trivial dependence on the choice of a spin structure which can be encoded combinatorially in a certain refinement of the ideal triangulation. By constructing a projective unitary representation of the groupoid of changes of refined ideal triangulations we demonstrate that the dependence of the resulting quantum theory on the choice of a triangulation is inessential.

  14. The super W∞ algebra

    International Nuclear Information System (INIS)

    Bergshoeff, E.; Pope, C.N.; Sezgin, E.; Shen, X.; Romans, L.J.

    1990-01-01

    We construct a higher-spin N=2 superalgebra whose bosonic sector is W ∞ +W 1+∞ . It can be realised in terms of bilinear currents involving free complex bosonic and fermionic fields. We also discuss the spectral flow, and various truncations. (orig.)

  15. A note on the super AKNS equations

    International Nuclear Information System (INIS)

    Li Yishen; Zhang Lining.

    1986-10-01

    We find some relationships between the usual AKNS scheme with the super one, when its elements take value from the Grassmann algebra on a two-dimensional vector space. The solutions of these super AKNS equations are discussed. (author)

  16. Venus Elongation Measurements for the Transit of Venus, using the ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 11. Venus Elongation Measurements for the Transit of Venus, using the Historical Jantar Mantar Observatory. N Rathnasree. Classroom Volume 9 Issue 11 November 2004 pp 46-55 ...

  17. Determinants of Elongation of the Labia Minora in Tete Province ...

    African Journals Online (AJOL)

    AJRH Managing Editor

    women may not report current vaginal ill health, it is possible that prospective cohort ... Keywords: Labia minora elongation; vaginal practices; Mozambique; survey; cross-sectional studies. ..... had ever had vaginal discharge, which was most.

  18. The Mediator complex: a master coordinator of transcription and cell lineage development.

    Science.gov (United States)

    Yin, Jing-wen; Wang, Gang

    2014-03-01

    Mediator is a multiprotein complex that is required for gene transcription by RNA polymerase II. Multiple subunits of the complex show specificity in relaying information from signals and transcription factors to the RNA polymerase II machinery, thus enabling control of the expression of specific genes. Recent studies have also provided novel mechanistic insights into the roles of Mediator in epigenetic regulation, transcriptional elongation, termination, mRNA processing, noncoding RNA activation and super enhancer formation. Based on these specific roles in gene regulation, Mediator has emerged as a master coordinator of development and cell lineage determination. Here, we describe the most recent advances in understanding the mechanisms of Mediator function, with an emphasis on its role during development and disease.

  19. The super-classical-Boussinesq hierarchy and its super-Hamiltonian structure

    International Nuclear Information System (INIS)

    Si-Xing, Tao; Tie-Cheng, Xia

    2010-01-01

    Based on the constructed Lie superalgebra, the super-classical-Boussinesq hierarchy is obtained. Then, its super-Hamiltonian structure is obtained by making use of super-trace identity. Furthermore, the super-classical-Boussinesq hierarchy is also integrable in the sense of Liouville. (general)

  20. Research and development of super light water reactors and super fast reactors in Japan

    International Nuclear Information System (INIS)

    Oka, Y.; Morooka, S.; Yamakawa, M.; Ishiwatari, Y.; Ikejiri, S.; Katsumura, Y.; Muroya, Y.; Terai, T.; Sasaki, K.; Mori, H.; Hamamoto, Y.; Okumura, K.; Kugo, T.; Nakatsuka, T.; Ezato, K.; Akasaka, N.; Hotta, A.

    2011-01-01

    Super Light Water Reactors (Super LWR) and Super Fast Reactors (Super FR) are the supercritical- pressure light water cooled reactors (SCWR) that are developed by the research group of University of Tokyo since 1989 and now jointly under development with the researchers of Waseda University, University of Tokyo and other organizations in Japan. The principle of the reactor concept development, the results of the past Super LWR and Super FR R&D as well as the R&D program of the Super FR second phase project are described. (author)

  1. Supergrassmannians, super τ-functions and strings

    International Nuclear Information System (INIS)

    Dolgikh, S.N.; Schwarz, A.S.

    1989-03-01

    Recently, infinite-dimensional grassmannians and their supergeneralizations were used to study conformal two-dimensional fields and strings. In particular, the super Mumford form (holomorphic square root from the superstring measure on moduli space) was expressed through super analog of Sato τ-function. In this paper we present results of supergrassmannians and super τ-functions. 8 refs

  2. Super Virasoro algebra and solvable supersymmetric quantum field theories

    International Nuclear Information System (INIS)

    Yamanaka, Itaru; Sasaki, Ryu.

    1987-09-01

    Interesting and deep relationships between super Virasoro algebras and super soliton systems (super KdV, super mKdV and super sine-Gordon equations) are investigated at both classical and quantum levels. An infinite set of conserved quantities responsible for solvability is characterized by super Virasoro algebras only. Several members of the infinite set of conserved quantities are derived explicitly. (author)

  3. One-dimensional super Calabi-Yau manifolds and their mirrors

    Energy Technology Data Exchange (ETDEWEB)

    Noja, S. [Dipartimento di Matematica, Università degli Studi di Milano,Via Saldini 50, I-20133 Milano (Italy); Cacciatori, S.L. [Dipartimento di Scienza e Alta Tecnologia, Università dell’Insubria, Via Valleggio 11, I-22100 Como (Italy); INFN, Sezione di Milano,Via Celoria 16, I-20133 Milano (Italy); Piazza, F. Dalla [Dipartimento di Scienza e Alta Tecnologia, Università dell’Insubria, Via Valleggio 11, I-22100 Como (Italy); Marrani, A. [Centro Studi e Ricerche ‘Enrico Fermi’,Via Panisperna 89A, I-00184 Roma (Italy); Dipartimento di Fisica e Astronomia ‘Galileo Galilei’, Università di Padova,and INFN, Sezione di Padova,Via Marzolo 8, I-35131 Padova (Italy); Re, R. [Dipartimento di Matematica e Informatica, Università degli Studi di Catania,Viale Andrea Doria 6, 95125 Catania (Italy)

    2017-04-18

    We apply a definition of generalised super Calabi-Yau variety (SCY) to supermanifolds of complex dimension one. One of our results is that there are two SCY’s having reduced manifold equal to ℙ{sup 1}, namely the projective super space ℙ{sup 1|2} and the weighted projective super space Wℙ{sub (2)}{sup 1|1}. Then we compute the corresponding sheaf cohomology of superforms, showing that the cohomology with picture number one is infinite dimensional, while the de Rham cohomology, which is what matters from a physical point of view, remains finite dimensional. Moreover, we provide the complete real and holomorphic de Rham cohomology for generic projective super spaces ℙ{sup n|m}. We also determine the automorphism groups: these always match the dimension of the projective super group with the only exception of ℙ{sup 1|2}, whose automorphism group turns out to be larger than the projective super group. By considering the cohomology of the super tangent sheaf, we compute the deformations of ℙ{sup 1|m}, discovering that the presence of a fermionic structure allows for deformations even if the reduced manifold is rigid. Finally, we show that ℙ{sup 1|2} is self-mirror, whereas Wℙ{sub (2)}{sup 1|1} has a zero dimensional mirror. Also, the mirror map for ℙ{sup 1|2} naturally endows it with a structure of N=2 super Riemann surface.

  4. Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator.

    Science.gov (United States)

    Mehlgarten, Constance; Prochaska, Heike; Hammermeister, Alexander; Abdel-Fattah, Wael; Wagner, Melanie; Krutyhołowa, Rościsław; Jun, Sang Eun; Kim, Gyung-Tae; Glatt, Sebastian; Breunig, Karin D; Stark, Michael J R; Schaffrath, Raffael

    2017-09-05

    Saccharomyces cerevisiae cells are killed by zymocin, a tRNase ribotoxin complex from Kluyveromyces lactis , which cleaves anticodons and inhibits protein synthesis. Zymocin's action requires specific chemical modification of uridine bases in the anticodon wobble position (U34) by the Elongator complex (Elp1-Elp6). Hence, loss of anticodon modification in mutants lacking Elongator or related KTI ( K. lactis Toxin Insensitive) genes protects against tRNA cleavage and confers resistance to the toxin. Here, we show that zymocin can be used as a tool to genetically analyse KTI12 , a gene previously shown to code for an Elongator partner protein. From a kti12 mutant pool of zymocin survivors, we identify motifs in Kti12 that are functionally directly coupled to Elongator activity. In addition, shared requirement of U34 modifications for nonsense and missense tRNA suppression ( SUP4 ; SOE1 ) strongly suggests that Kti12 and Elongator cooperate to assure proper tRNA functioning. We show that the Kti12 motifs are conserved in plant ortholog DRL1/ELO4 from Arabidopsis thaliana and seem to be involved in binding of cofactors (e.g., nucleotides, calmodulin). Elongator interaction defects triggered by mutations in these motifs correlate with phenotypes typical for loss of U34 modification. Thus, tRNA modification by Elongator appears to require physical contact with Kti12, and our preliminary data suggest that metabolic signals may affect proper communication between them.

  5. The Super-B project accelerator status

    CERN Document Server

    Biagini, M.E.; Boni, R; Boscolo, M; Demma, T; Drago, A; Esposito, M; Guiducci, S; Marcellini, F; Mazzitelli, G; Preger, M; Raimondi, P; Sanelli, C; Serio, M; Stecchi, A; Stella, A; Tomassini, S; Zobov, M; Bertsche, K; Brachmann, A; Cai, Y; Chao, A; DeLira, A; Donald, M; Fisher, A; Kharakh, D; Krasnykh, A; Li, N; MacFarlane, D; Nosochkov, Y; Novokhatski, A; Pivi, M.; Seeman, J; Sullivan, M; Wienands, U; Weisend, J; Wittmer, W; Koop, I; Levichev, E; Nikitin, S; Piminov, P; Sinyatkin, S; Shatilov, D; Bolzon, B; Brunetti, L; Jeremie, A; Baylac, M; DeConto, J M; Gomez, Y; Meot, F; Monseu, N; Tourres, D; Bonis, J.; Chehab, R; Le Meur, G; Mercier, B; Poirier, F; Prevost, C; Rimbault, C; Touze, F; Variola, A; Chance, A; Napoly, O; Bosi, F; Liuzzo, S; Paoloni, E; Bettoni, S

    2010-01-01

    The SuperB project is an international effort aiming at building in Italy a very high luminosity e+e- (1036 cm-2 sec-1) asymmetric collider at the Y(4S) energy in the cm. The accelerator design has been extensively studied and changed during the past year. The present design, based on the new collision scheme, with large Piwinski angle and the use of “crab waist” sextupoles already successfully tested at the DANE -Factory at LNF Frascati, provides larger flexibility, better dynamic aperture and spin manipulation sections in the Low Energy Ring (LER) for longitudinal polarization of the electron beam at the Interaction Point (IP). The Interaction Region (IR) has been further optimized in terms of apertures and reduced backgrounds in the detector. The injector complex design has been also updated. A summary of the project status will be presented in this paper

  6. Film dosimetry of small elongated electron beams for treatment planning

    International Nuclear Information System (INIS)

    Niroomand-Rad, A.

    1989-01-01

    The characteristics of 5, 7, 10, 12, 15, and 18 Mev electron beams for small elongated fields of dimensions L x W (where L=1, 2, 3, 4, 5, and 10 cm; and W=1, 2, 3, 4, 5, and 10 cm) have been studied. Film dosimetry and parallel-plate ion chamber measurements have been used to obtain various dose parameters. Selective results of a series of systematic measurements for central axis depth dose data, uniformity index, field flatness, and relative output factors of small elongated electron beams are reported. The square-root method is employed to predict the beam data of small elongated electron fields from corresponding small square electron fields using film dosimetry. The single parameter area/perimeter radio A/P is used to characterize the relative output factors of elongated electron beams. It is our conclusion that for clinical treatment planning square-root method may be applied with caution in determining the beam characteristics of small elongated electron fields from film dosimetry. The calculated and estimated relative output factors from square-root method and A/P ratio are in good agreement and show agreement to within 1% with the measured film values

  7. Amphiregulin Antibody and Reduction of Axial Elongation in Experimental Myopia

    Directory of Open Access Journals (Sweden)

    Wen Jun Jiang

    2017-03-01

    Full Text Available To examine the mechanism of ocular axial elongation in myopia, guinea pigs (age: 2–3 weeks which either underwent unilateral or bilateral lens-induced myopization (group 1 or which were primarily myopic at baseline (group 2 received unilateral intraocular injections of amphiregulin antibody (doses: 5, 10, or 15 μg three times in intervals of 9 days. A third group of emmetropic guinea pigs got intraocular unilateral injections of amphiregulin (doses: 0.25, 0.50 or 1.00 ng, respectively. In each group, the contralateral eyes received intraocular injections of Ringer's solution. In intra-animal inter-eye comparison and intra-eye follow-up comparison in groups 1 and 2, the study eyes as compared to the contralateral eyes showed a dose-dependent reduction in axial elongation. In group 3, study eyes and control eyes did not differ significantly in axial elongation. Immunohistochemistry revealed amphiregulin labelling at the retinal pigment epithelium in eyes with lens-induced myopization and Ringer's solution injection, but not in eyes with amphiregulin antibody injection. Intraocular injections of amphiregulin-antibody led to a reduction of lens-induced axial myopic elongation and of the physiological eye enlargement in young guinea pigs. In contrast, intraocularly injected amphiregulin in a dose of ≤1 ng did not show a significant effect. Amphiregulin may be one of several essential molecular factors for axial elongation.

  8. Super-stable Poissonian structures

    International Nuclear Information System (INIS)

    Eliazar, Iddo

    2012-01-01

    In this paper we characterize classes of Poisson processes whose statistical structures are super-stable. We consider a flow generated by a one-dimensional ordinary differential equation, and an ensemble of particles ‘surfing’ the flow. The particles start from random initial positions, and are propagated along the flow by stochastic ‘wave processes’ with general statistics and general cross correlations. Setting the initial positions to be Poisson processes, we characterize the classes of Poisson processes that render the particles’ positions—at all times, and invariantly with respect to the wave processes—statistically identical to their initial positions. These Poisson processes are termed ‘super-stable’ and facilitate the generalization of the notion of stationary distributions far beyond the realm of Markov dynamics. (paper)

  9. Super-stable Poissonian structures

    Science.gov (United States)

    Eliazar, Iddo

    2012-10-01

    In this paper we characterize classes of Poisson processes whose statistical structures are super-stable. We consider a flow generated by a one-dimensional ordinary differential equation, and an ensemble of particles ‘surfing’ the flow. The particles start from random initial positions, and are propagated along the flow by stochastic ‘wave processes’ with general statistics and general cross correlations. Setting the initial positions to be Poisson processes, we characterize the classes of Poisson processes that render the particles’ positions—at all times, and invariantly with respect to the wave processes—statistically identical to their initial positions. These Poisson processes are termed ‘super-stable’ and facilitate the generalization of the notion of stationary distributions far beyond the realm of Markov dynamics.

  10. swot: Super W Of Theta

    Science.gov (United States)

    Coupon, Jean; Leauthaud, Alexie; Kilbinger, Martin; Medezinski, Elinor

    2017-07-01

    SWOT (Super W Of Theta) computes two-point statistics for very large data sets, based on “divide and conquer” algorithms, mainly, but not limited to data storage in binary trees, approximation at large scale, parellelization (open MPI), and bootstrap and jackknife resampling methods “on the fly”. It currently supports projected and 3D galaxy auto and cross correlations, galaxy-galaxy lensing, and weighted histograms.

  11. BEWARE OF...SUPER GLUES!!

    CERN Multimedia

    2006-01-01

    What happened? A number of accidents have occurred with the use of 'Super Glues'. Some individuals have suffered injuries - severe irritation, or skin bonded together - through getting glue on their face and in their eyes. What are the hazards associated with glues? 'Super Glues' (i.e. cyanoacrylates): Are harmful if swallowed and are chemical irritants to the eyes, respiratory system and skin. Present the risk of polymerization (hardening) leading to skin damage. Be careful ! 'Super Glues' can bond to skin and eyes in seconds. Note: Other glues, resins and hardeners are also chemicals and as such can cause serious damage to the skin, eyes, respiratory or digestive tract. (For example: some components can be toxic, harmful, corrosive, sensitizing agents, etc.). How to prevent accidents in the future? Read the Material Safety Data Sheet (MSDS) for all of the glues you work with. Check the label on the container to find out which of the materials you work with are hazardous. Wear the right Per...

  12. Status of the tube elongation problem as of June 1976

    International Nuclear Information System (INIS)

    Alexander, W.K.

    1976-01-01

    It was discovered in May of 1971 that the N Reactor process tubes had apparently increased in length by as much as one inch. Preliminary observations and measurements led to the tentative conclusion that this observed elongation was linear with accumulated tube exposure and also that it was related in some manner to the tube fabrication process. It appeared that the observed elongation was approximately proportional to the degree of cold work retained in the finished tubes. This latter conclusion was based on the observation that those tubes with approximately 17-18 percent cold work had elongated only about half as much as the standard 30-percent-cold-worked tubes. It was immediately recognized that if such elongation was to continue unchecked it could pose a limit to reactor life since total possible tube expansion, from all causes, is limited to 1.75 inches by nozzle design considerations as shown in Figure 1. Thermal and hydraulic expansion were calculated to total approximately 0.75 inches which left only one inch available to accommodate tube growth or creep. Since discovery of this phenomenon, an extensive measurements program has been carried out to evaluate the extent and rate of tube elongation. Two corrective approaches have been developed and a small number of tubes were modified by each method during the 1976 summer outage. During the 1974, 1975 and 1976 Summer Outages, measurements were made on all tubes to determine the clearance remaining between the nozzle keys and the gas packing ring. These readings not only give an overall picture of the extent of elongation, but also provide immediate data indicating which tubes are about out of clearance. The report presents an evaluation of the measurements taken to date

  13. Application Feasibility of PRE 50 grade Super Austenitic Stainless Steel as a Steam Generator Tubing

    Energy Technology Data Exchange (ETDEWEB)

    Park, Yong Soo [Yonsei University, Seoul (Korea, Republic of); Kim, Young sik [Andong National University, Andong (Korea, Republic of); Kim, Taek Jun; Kim, Sun Tae; Park, Hui Sang [Yonsei University, Seoul (Korea, Republic of)

    1997-07-01

    The aim of this study is to evaluate the properties of the super austenitic stainless steel, SR-50A for application as steam generator tubing material. The microstructure, mechanical properties, corrosion properties, were analyzed and the results were compared between super austenitic stainless steel and Alloy 600 and Alloy 690. Super austenitic stainless steel, SR-50A is superior to Alloy 600, Alloy 690 and Alloy 800 in the mechanical properties(tensile strength, yield strength, and elongation). It was investigated that thermal conductivity of SR-50A was higher than Alloy 600. As a result of thermal treatment on super stainless steel, SR-50A, caustic SCC resistance was increased and its resistance was as much as Alloy 600TT and Alloy 690TT. In this study, optimum thermal treatment condition to improve the caustic corrosion properties was considered as 650 deg C or 550 deg C 15 hours. However, it is necessary to verify the corrosion mechanism and to prove the above results in the various corrosive environments. 27 refs., 6 tabs., 59 figs. (author)

  14. Investigation of Fano resonances induced by higher order plasmon modes on a circular nano-disk with an elongated cavity

    KAUST Repository

    Amin, Muhammad Ruhul

    2012-08-10

    In this paper, a planar metallic nanostructure design, which supports two distinct Fano resonances in its extinction cross-section spectrum under normally incident and linearly polarized electromagnetic field, is proposed. The proposed design involves a circular disk embedding an elongated cavity; shifting and rotating the cavity break the symmetry of the structure with respect to the incident field and induce higher order plasmon modes. As a result, Fano resonances are generated in the visible spectrum due to the destructive interference between the sub-radiant higher order modes and super-radiant the dipolar mode. The Fano resonances can be tuned by varying the cavity\\'s width and the rotation angle. An RLC circuit, which is mathematically equivalent to a mass-spring oscillator, is proposed to model the optical response of the nanostructure design.

  15. Viscosity overshoot in the start-up of uniaxial elongation of low density polyethylene melts

    DEFF Research Database (Denmark)

    Rasmussen, Henrik K.; Nielsen, Jens Kromann; Bach, Anders

    2005-01-01

    The transient uniaxial elongational viscosity of BASF Lupolen 1840D and 3020D melts has been measured on a filament stretch rheometer up to Hencky strains of 6-7. The elongational viscosity of both melts was measured at 130 degrees C within a broad range of elongational rates. At high elongation ...

  16. Optimal super dense coding over memory channels

    OpenAIRE

    Shadman, Zahra; Kampermann, Hermann; Macchiavello, Chiara; Bruß, Dagmar

    2011-01-01

    We study the super dense coding capacity in the presence of quantum channels with correlated noise. We investigate both the cases of unitary and non-unitary encoding. Pauli channels for arbitrary dimensions are treated explicitly. The super dense coding capacity for some special channels and resource states is derived for unitary encoding. We also provide an example of a memory channel where non-unitary encoding leads to an improvement in the super dense coding capacity.

  17. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence

    DEFF Research Database (Denmark)

    Taskova, Maria; Uhd, Jesper; Miotke, Laura

    2017-01-01

    opportunities in transcriptome analysis, virology, and other fields. Herein, we report for the first time a "click" chemistry approach to oligonucleotide probe elongation as a novel approach to specifically detect a viral sequence. We hybridized a library of short, terminally labeled probes to Ebola virus RNA...

  18. Longitudinal domain wall formation in elongated assemblies of ferromagnetic nanoparticles

    DEFF Research Database (Denmark)

    Varón, Miriam; Beleggia, Marco; Jordanovic, Jelena

    2015-01-01

    Through evaporation of dense colloids of ferromagnetic ~13 nm ε-Co particles onto carbon substrates, anisotropic magnetic dipolar interactions can support formation of elongated particle structures with aggregate thicknesses of 100-400 nm and lengths of up to some hundred microns. Lorenz microsco...

  19. Visualization of elongation measurements using an SER universal testing platform

    Czech Academy of Sciences Publication Activity Database

    Pivokonský, Radek; Filip, Petr; Zelenková, Jana

    2015-01-01

    Roč. 25, č. 1 (2015), s. 1-8 ISSN 1430-6395 R&D Projects: GA ČR(CZ) GAP105/11/2342 Institutional support: RVO:67985874 Keywords : elongational viscosity * Universal Testing Platform (SER) * polymer melts * LDPE Subject RIV: BK - Fluid Dynamics Impact factor: 1.241, year: 2015

  20. Bilateral elongated styloid process: Its anatomical, embryological and clinical implications

    Directory of Open Access Journals (Sweden)

    Bagoji Ishwar B, Hadimani Gavishiddappa A, Patil Balasaheb G, Bannur Balappa M,Ambadasu B

    2013-04-01

    Full Text Available The styloid process is a slender, elongated, cylindrical bony projection from temporal bone. It normally varies in length from 2 cm to 3 cm. During a routine demonstration of skull for MBBS students we found the bilateral elongated styloid process in dry human skull. The length of elongation measured on the right and left side was 6.0 & 5.9 cms respectively. Such abnormal elongation of the styloid process may cause compression on a number of vital vessels and nerves related to it, producing inflammatory changes that include continuous chronic pain in the pharyngeal region. Mechanical stresses stretching the second brachial arch during fetal development probably induce variable involvement of Reichert’s cartilage in morphogenesis of the styloid process. It is important that clinicians especially dentists and otolaryngologists are aware of the natural variations of the styloid process and do not consider the styloid process with a length of 30 mm as an abnormality or as an anomaly.

  1. One-step purification of E. coli elongation factor Tu

    DEFF Research Database (Denmark)

    Knudsen, Charlotte Rohde; Clark, Brian F. C.; Degn, B

    1993-01-01

    The tuf A gene, encoding the E. coli elongation factor Tu, was cloned in the pGEX gene fusion system. Upon expression EF-Tu is fused to glutathione-S-transferase serving as a purification handle with affinity for glutathione immobilised on agarose. This allows purification of EF-Tu in a one...

  2. SuperMAG: Present and Future Capabilities

    Science.gov (United States)

    Hsieh, S. W.; Gjerloev, J. W.; Barnes, R. J.

    2009-12-01

    SuperMAG is a global collaboration that provides ground magnetic field perturbations from a long list of stations in the same coordinate system, identical time resolution and with a common baseline removal approach. This unique high quality dataset provides a continuous and nearly global monitoring of the ground magnetic field perturbation. Currently, only archived data are available on the website and hence it targets basic research without any operational capabilities. The existing SuperMAG software can be easily adapted to ingest real-time or near real-time data and provide a now-casting capability. The SuperDARN program has a long history of providing near real-time maps of the northern hemisphere electrostatic potential and as both SuperMAG and SuperDARN share common software it is relatively easy to adapt these maps for global magnetic perturbations. Magnetometer measurements would be assimilated by the SuperMAG server using a variety of techniques, either by downloading data at regular intervals from remote servers or by real-time streaming connections. The existing SuperMAG analysis software would then process these measurements to provide the final calibrated data set using the SuperMAG coordinate system. The existing plotting software would then be used to produce regularly updated global plots. The talk will focus on current SuperMAG capabilities illustrating the potential for now-casting and eventually forecasting.

  3. Characterization of a NIMONIC TYPE super alloy

    International Nuclear Information System (INIS)

    Zamora Rangel, L.; Martinez Martinez, E.

    1985-01-01

    Mechanical properties of strength and thermofluence of a NIMONIC type super alloy under thermal treatment was determined. The relationship between microstructure, phases and precipitates was also studied. (author)

  4. (Super Variable Costing-Throughput Costing)

    OpenAIRE

    Çakıcı, Cemal

    2006-01-01

    (Super Variable Costing-Throughput Costing) The aim of this study is to explain the super-variable costing method which is a new subject in cost and management accounting and to show it’s working practicly.Shortly, super-variable costing can be defined as a costing method which is use only direct material costs in calculate of product costs and treats all costs except these (direct labor and overhead) as periad costs or operating costs.By using super-variable costing method, product costs ar...

  5. Adenylate cyclase regulates elongation of mammalian primary cilia

    International Nuclear Information System (INIS)

    Ou, Young; Ruan, Yibing; Cheng, Min; Moser, Joanna J.; Rattner, Jerome B.; Hoorn, Frans A. van der

    2009-01-01

    The primary cilium is a non-motile microtubule-based structure that shares many similarities with the structures of flagella and motile cilia. It is well known that the length of flagella is under stringent control, but it is not known whether this is true for primary cilia. In this study, we found that the length of primary cilia in fibroblast-like synoviocytes, either in log phase culture or in quiescent state, was confined within a range. However, when lithium was added to the culture to a final concentration of 100 mM, primary cilia of synoviocytes grew beyond this range, elongating to a length that was on average approximately 3 times the length of untreated cilia. Lithium is a drug approved for treating bipolar disorder. We dissected the molecular targets of this drug, and observed that inhibition of adenylate cyclase III (ACIII) by specific inhibitors mimicked the effects of lithium on primary cilium elongation. Inhibition of GSK-3β by four different inhibitors did not induce primary cilia elongation. ACIII was found in primary cilia of a variety of cell types, and lithium treatment of these cell types led to their cilium elongation. Further, we demonstrate that different cell types displayed distinct sensitivities to the lithium treatment. However, in all cases examined primary cilia elongated as a result of lithium treatment. In particular, two neuronal cell types, rat PC-12 adrenal medulla cells and human astrocytes, developed long primary cilia when lithium was used at or close to the therapeutic relevant concentration (1-2 mM). These results suggest that the length of primary cilia is controlled, at least in part, by the ACIII-cAMP signaling pathway.

  6. Adenylate cyclase regulates elongation of mammalian primary cilia

    Energy Technology Data Exchange (ETDEWEB)

    Ou, Young; Ruan, Yibing; Cheng, Min; Moser, Joanna J. [Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1 (Canada); Rattner, Jerome B. [Department of Cell Biology and Anatomy, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1 (Canada); Hoorn, Frans A. van der, E-mail: fvdhoorn@ucalgary.ca [Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1 (Canada)

    2009-10-01

    The primary cilium is a non-motile microtubule-based structure that shares many similarities with the structures of flagella and motile cilia. It is well known that the length of flagella is under stringent control, but it is not known whether this is true for primary cilia. In this study, we found that the length of primary cilia in fibroblast-like synoviocytes, either in log phase culture or in quiescent state, was confined within a range. However, when lithium was added to the culture to a final concentration of 100 mM, primary cilia of synoviocytes grew beyond this range, elongating to a length that was on average approximately 3 times the length of untreated cilia. Lithium is a drug approved for treating bipolar disorder. We dissected the molecular targets of this drug, and observed that inhibition of adenylate cyclase III (ACIII) by specific inhibitors mimicked the effects of lithium on primary cilium elongation. Inhibition of GSK-3{beta} by four different inhibitors did not induce primary cilia elongation. ACIII was found in primary cilia of a variety of cell types, and lithium treatment of these cell types led to their cilium elongation. Further, we demonstrate that different cell types displayed distinct sensitivities to the lithium treatment. However, in all cases examined primary cilia elongated as a result of lithium treatment. In particular, two neuronal cell types, rat PC-12 adrenal medulla cells and human astrocytes, developed long primary cilia when lithium was used at or close to the therapeutic relevant concentration (1-2 mM). These results suggest that the length of primary cilia is controlled, at least in part, by the ACIII-cAMP signaling pathway.

  7. Super rogue wave in plasma

    International Nuclear Information System (INIS)

    Pathak, Pallabi; Sharma, Sumita Kumari; Bailung, Heremba

    2015-01-01

    The evolution of super rogue wave having amplitude ∼5 times the background wave has been observed in multicomponent plasma with critical concentration of negative ions in a double plasma device. In normal electron-ion plasma the ion acoustic solitons are described by the Korteweg-de Vries (KdV) equation. At a critical concentration of negative ions, the ion acoustic modified KdV solitons are found to propagate. Multicomponent plasma also supports the propagation of a special kind of soliton namely 'Peregrine soliton' at critical concentration of negative ions. Peregrine soliton is a doubly localized solution of the nonlinear Schrodinger equation (NLSE) having amplitude 3 times the background carrier wave. In a double plasma device, ion-acoustic Peregrine soliton is excited by applying slowly varying amplitude modulated continuous sinusoidal signal to the source anode and described by the rational solution of NLSE. The ion acoustic wave is modulationally unstable in multicomponent plasma with critical concentration of negative ions and an initial modulated wave perturbation is found to undergo self-modulation to form localized structures by balancing the nonlinearity with the dispersion. In presence of higher order nonlinearity, propagation of a high amplitude (∼5 times of background carrier wave) ion acoustic Peregrine soliton has been observed experimentally. The existence of such types of higher order wave has been reported in other dispersive media. These are considered to be the prototype of super rogue wave in deep water. In this work, experimental results on the evolution of super rogue wave in a double plasma device are presented and compared with the numerical solution of NLSE. (author)

  8. The super W∞ symmetry of the Manin-Radul super KP hierarchy

    International Nuclear Information System (INIS)

    Das, A.; Sin, S.J.

    1991-11-01

    We show that the Manin-Radul super KP hierarchy is invariant under super W ∞ transformations. These transformations are characterized by time dependent flows which commute with the usual flows generated by the conserved quantities of the super KP hierarchy. (author). 16 refs

  9. The Super-Kamiokande experiment

    International Nuclear Information System (INIS)

    Nishijima, K.

    2000-01-01

    The Super-Kamiokande experiment is a multi purpose experiment using a large imaging water Cherenkov detector with 50,000 tons of pure water. The detector is located 1000 m underground in the Kamioka mine in Japan, and it can detect particle interactions whose visible energies are between 5 MeV and 100 GeV, so that we can study many physics subjects as follows. Solar neutrino problem is one of the most important unsolved problems in astrophysics. Kamiokande experiment confirmed the deficit of neutrino flux compared to the standard Solar model prediction, which was first reported by R. Davis's pioneering work. Currently it is widely believed that the deficit is due to the neutrino oscillation. The Super-Kamiokande is a unique detector to measure the distortion of the energy spectrum of neutrinos, variation of the neutrino flux between day and night, and the seasonal variation of the flux. Those are related to the neutrino oscillation and independent of the Solar model uncertainty. Atmospheric neutrino anomaly was first announced by Kamiokande experiment, and the Super-Kamiokande recently provided clear evidence for neutrino oscillation as the solution to the anomaly. Observed ratio of muons to electrons is significantly smaller than what is expected. Moreover, zenith-angle distribution of observed muon neutrinos shows the strong up-down asymmetry. The zenith angle distribution of upward-going muons provides another information and the result also supports the oscillation hypothesis. We investigate not only the Solar neutrino problem and atmospheric neutrino anomaly, but also other astrophysical neutrino phenomena such as neutrino bursts from supernova explosions, high energy neutrino emission from point sources, neutrino events in correlation with Solar flares, and gamma-ray bursts. Search for nucleon decay is also one of the primary objectives of our experiment. However no evidence for nucleon decay has been observed yet, and we only set a lower limit on the partial

  10. Notes on super Killing tensors

    Energy Technology Data Exchange (ETDEWEB)

    Howe, P.S. [Department of Mathematics, King’s College London,The Strand, London WC2R 2LS (United Kingdom); Lindström, University [Department of Physics and Astronomy, Theoretical Physics, Uppsala University,SE-751 20 Uppsala (Sweden); Theoretical Physics, Imperial College London,Prince Consort Road, London SW7 2AZ (United Kingdom)

    2016-03-14

    The notion of a Killing tensor is generalised to a superspace setting. Conserved quantities associated with these are defined for superparticles and Poisson brackets are used to define a supersymmetric version of the even Schouten-Nijenhuis bracket. Superconformal Killing tensors in flat superspaces are studied for spacetime dimensions 3,4,5,6 and 10. These tensors are also presented in analytic superspaces and super-twistor spaces for 3,4 and 6 dimensions. Algebraic structures associated with superconformal Killing tensors are also briefly discussed.

  11. Highlights from Super-Kamiokande

    International Nuclear Information System (INIS)

    Okumura, Kimihiro

    2016-01-01

    Recent results from Super-Kamiokande experiment are reviewed in this paper; Neutrino mass hierarchy and CP violation in the lepton sector are investigated via ν_μ → ν_e oscillation of the atmospheric neutrinos. The event rate, correlation with solar activity, energy spectrum of the solar neutrinos are measured via electron elastic scattering interactions. Neutrino emission from the WIMP annihilation at the center of the Sun are searched in the GeV energy regions. New project, SK-Gd project, to enhance anti-neutrino identification capability, has been approved inside the collaboration group

  12. Video Super-Resolution via Bidirectional Recurrent Convolutional Networks.

    Science.gov (United States)

    Huang, Yan; Wang, Wei; Wang, Liang

    2018-04-01

    Super resolving a low-resolution video, namely video super-resolution (SR), is usually handled by either single-image SR or multi-frame SR. Single-Image SR deals with each video frame independently, and ignores intrinsic temporal dependency of video frames which actually plays a very important role in video SR. Multi-Frame SR generally extracts motion information, e.g., optical flow, to model the temporal dependency, but often shows high computational cost. Considering that recurrent neural networks (RNNs) can model long-term temporal dependency of video sequences well, we propose a fully convolutional RNN named bidirectional recurrent convolutional network for efficient multi-frame SR. Different from vanilla RNNs, 1) the commonly-used full feedforward and recurrent connections are replaced with weight-sharing convolutional connections. So they can greatly reduce the large number of network parameters and well model the temporal dependency in a finer level, i.e., patch-based rather than frame-based, and 2) connections from input layers at previous timesteps to the current hidden layer are added by 3D feedforward convolutions, which aim to capture discriminate spatio-temporal patterns for short-term fast-varying motions in local adjacent frames. Due to the cheap convolutional operations, our model has a low computational complexity and runs orders of magnitude faster than other multi-frame SR methods. With the powerful temporal dependency modeling, our model can super resolve videos with complex motions and achieve well performance.

  13. Elongator Plays a Positive Role in Exogenous NAD-Induced Defense Responses in Arabidopsis.

    Science.gov (United States)

    An, Chuanfu; Ding, Yezhang; Zhang, Xudong; Wang, Chenggang; Mou, Zhonglin

    2016-05-01

    Extracellular NAD is emerging as an important signal molecule in animal cells, but its role in plants has not been well-established. Although it has been shown that exogenous NAD(+) activates defense responses in Arabidopsis, components in the exogenous NAD(+)-activated defense pathway remain to be fully discovered. In a genetic screen for mutants insensitive to exogenous NAD(+) (ien), we isolated a mutant named ien2. Map-based cloning revealed that IEN2 encodes ELONGATA3 (ELO3)/AtELP3, a subunit of the Arabidopsis Elongator complex, which functions in multiple biological processes, including histone modification, DNA (de)methylation, and transfer RNA modification. Mutations in the ELO3/AtELP3 gene compromise exogenous NAD(+)-induced expression of pathogenesis-related (PR) genes and resistance to the bacterial pathogen Pseudomonas syringae pv. maculicola ES4326, and transgenic expression of the coding region of ELO3/AtELP3 in elo3/Atelp3 restores NAD(+) responsiveness to the mutant plants, demonstrating that ELO3/AtELP3 is required for exogenous NAD(+)-induced defense responses. Furthermore, mutations in genes encoding the other five Arabidopsis Elongator subunits (ELO2/AtELP1, AtELP2, ELO1/AtELP4, AtELP5, and AtELP6) also compromise exogenous NAD(+)-induced PR gene expression and resistance to P. syringae pv. maculicola ES4326. These results indicate that the Elongator complex functions as a whole in exogenous NAD(+)-activated defense signaling in Arabidopsis.

  14. New idea on the classification of world super-large deposits

    International Nuclear Information System (INIS)

    Tong Hangshou

    2012-01-01

    According to the theory of 'multi factors and compound genesis', 'complexity of mineralization' and 'metallogenic series', this paper proposed a new classification idea on the world super-large deposits with the combination of new results on the study of global background for super-large deposits and the model of 'conjugation of multi-source and focus of multi-factors'. 15 super-large deposits with the reserve over 50000 t were studied as the ases, 6 types and 13 sub-types of economics-genesis have been divided for the super-large deposit. The classification is discoursed with symbols and worlds and brief introduction on typical deposit. (authors)

  15. Reduction of 4-dim self dual super Yang-Mills onto super Riemann surfaces

    International Nuclear Information System (INIS)

    Mendoza, A.; Restuccia, A.; Martin, I.

    1990-05-01

    Recently self dual super Yang-Mills over a super Riemann surface was obtained as the zero set of a moment map on the space of superconnections to the dual of the super Lie algebra of gauge transformations. We present a new formulation of 4-dim Euclidean self dual super Yang-Mills in terms of constraints on the supercurvature. By dimensional reduction we obtain the same set of superconformal field equations which define self dual connections on a super Riemann surface. (author). 10 refs

  16. Transition zone cells reach G2 phase before initiating elongation in maize root apex

    Directory of Open Access Journals (Sweden)

    M. Victoria Alarcón

    2017-06-01

    Full Text Available Root elongation requires cell divisions in the meristematic zone and cell elongation in the elongation zone. The boundary between dividing and elongating cells is called the transition zone. In the meristem zone, initial cells are continuously dividing, but on the basal side of the meristem cells exit the meristem through the transition zone and enter in the elongation zone, where they stop division and rapidly elongate. Throughout this journey cells are accompanied by changes in cell cycle progression. Flow cytometry analysis showed that meristematic cells are in cycle, but exit when they enter the elongation zone. In addition, the percentage of cells in G2 phase (4C strongly increased from the meristem to the elongation zone. However, we did not observe remarkable changes in the percentage of cells in cell cycle phases along the entire elongation zone. These results suggest that meristematic cells in maize root apex stop the cell cycle in G2 phase after leaving the meristem.

  17. Exact solution of super Liouville model

    International Nuclear Information System (INIS)

    Yang Zhanying; Zhao Liu; Zhen Yi

    2000-01-01

    Using Leznov-Saveliev algebraic analysis and Drinfeld-Sokolov construction, the authors obtained the explicit solutions to the super Liouville system in super covariant form and component form. The explicit solution in component form reduces naturally into the Egnchi-Hanson instanton solution of the usual Liouville equation if all the Grassmann odd components are set equal to zero

  18. Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase.

    Science.gov (United States)

    Lõoke, Marko; Maloney, Michael F; Bell, Stephen P

    2017-02-01

    Activation of the Mcm2-7 replicative DNA helicase is the committed step in eukaryotic DNA replication initiation. Although Mcm2-7 activation requires binding of the helicase-activating proteins Cdc45 and GINS (forming the CMG complex), an additional protein, Mcm10, drives initial origin DNA unwinding by an unknown mechanism. We show that Mcm10 binds a conserved motif located between the oligonucleotide/oligosaccharide fold (OB-fold) and A subdomain of Mcm2. Although buried in the interface between these domains in Mcm2-7 structures, mutations predicted to separate the domains and expose this motif restore growth to conditional-lethal MCM10 mutant cells. We found that, in addition to stimulating initial DNA unwinding, Mcm10 stabilizes Cdc45 and GINS association with Mcm2-7 and stimulates replication elongation in vivo and in vitro. Furthermore, we identified a lethal allele of MCM10 that stimulates initial DNA unwinding but is defective in replication elongation and CMG binding. Our findings expand the roles of Mcm10 during DNA replication and suggest a new model for Mcm10 function as an activator of the CMG complex throughout DNA replication. © 2017 Lõoke et al.; Published by Cold Spring Harbor Laboratory Press.

  19. Architectural Engineering to Super-Light Structures

    DEFF Research Database (Denmark)

    Castberg, Niels Andreas

    The increasing global urbanisation creates a great demand for new buildings. In the aim to honour this, a new structural system, offering flexibility and variation at no extra cost appears beneficial. Super-Light Structures constitute such a system. This PhD thesis examines Super-Light Structures...... with architectural engineering as a starting point. The thesis is based on a two stringed hypothesis: Architectural engineering gives rise to better architecture and Super-Light Structures support and enables a static, challenging architecture. The aim of the thesis is to clarify architectural engineering's impact...... on the work process between architects and engineers in the design development. Using architectural engineering, Super-Light Structures are examined in an architectural context, and it is explained how digital tools can support architectural engineering and design of Super-Light Structures. The experiences...

  20. Methanofullerene elongated nanostructure formation for enhanced organic solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Reyes-Reyes, M. [Instituto de Investigacion en Comunicacion Optica, Universidad Autonoma de San Luis Potosi, Alvaro Obregon 64, San Luis Potosi (Mexico)], E-mail: reyesm@cactus.iico.uaslp.mx; Lopez-Sandoval, R. [Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la presa San Jose 2055, CP 78216. San Luis Potosi (Mexico); Arenas-Alatorre, J. [Instituto de Fisica, UNAM, Apartado Postal 20-364, 01000, Mexico, D.F. (Mexico); Garibay-Alonso, R. [Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la presa San Jose 2055, CP 78216. San Luis Potosi (Mexico); Carroll, D.L. [Center for Nanotechnology and Molecular Materials, Department of Physics. Wake Forest University, Winston-Salem NC 27109 (United States); Lastras-Martinez, A. [Instituto de Investigacion en Comunicacion Optica, Universidad Autonoma de San Luis Potosi, Alvaro Obregon 64, San Luis Potosi (Mexico)

    2007-11-01

    Using transmission electron microscopy (TEM) and Z-contrast imaging we have demonstrated elongated nanostructure formation of fullerene derivative [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) within an organic host through annealing. The annealing provides an enhanced mobility of the PCBM molecules and, with good initial dispersion, allows for the formation of exaggerated grain growth within the polymer host. We have assembled these nanostructures within the regioregular conjugated polymer poly(3-hexylthiophene) (P3HT). This PCBM elongated nanostructure formation maybe responsible for the very high efficiencies observed, at very low loadings of PCBM (1:0.6, polymer to PCBM), in annealed photovoltaics. Moreover, our high resolution TEM and electron energy loss spectroscopy studies clearly show that the PCBM crystals remain crystalline and are unaffected by the 200-keV electron beam.

  1. IHH and FGF8 coregulate elongation of digit primordia.

    Science.gov (United States)

    Zhou, Jian; Meng, Junwei; Guo, Shengzhen; Gao, Bo; Ma, Gang; Zhu, Xuming; Hu, Jianxin; Xiao, Yue; Lin, Chuwen; Wang, Hongsheng; Ding, Lusheng; Feng, Guoyin; Guo, Xizhi; He, Lin

    2007-11-23

    In the developing limb bud, digit pattern arises from anterior-posterior (A-P) positional information which is provided by the concentration gradient of SHH. However, the mechanisms of translating early asymmetry into morphological form are still unclear. Here, we examined the ability of IHH and FGF8 signaling to regulate digital chondrogenesis, by implanting protein-loaded beads in the interdigital space singly and in combination. We found that IHH protein induced an elongated digit and that FGF8 protein blocked the terminal phalange formation. Molecular marker analysis showed that IHH expanded Sox9 expression in mesenchymal cells possibly through up-regulated FGF8 expression. Application of both IHH and FGF8 protein induced a large terminal phalange. These results suggest that both enhanced IHH and FGF8 signaling are required for the development of additional cartilage element in limbs. IHH and FGF8 maybe play different roles and act synergistically to promote chondrogenesis during digit primordia elongation.

  2. Cladding axial elongation models for FRAP-T6

    International Nuclear Information System (INIS)

    Shah, V.N.; Carlson, E.R.; Berna, G.A.

    1983-01-01

    This paper presents a description of the cladding axial elongation models developed at the Idaho National Engineering Laboratory (INEL) for use by the FRAP-T6 computer code in analyzing the response of fuel rods during reactor transients in light water reactors (LWR). The FRAP-T6 code contains models (FRACAS-II subcode) that analyze the structural response of a fuel rod including pellet-cladding-mechanical-interaction (PCMI). Recently, four models were incorporated into FRACAS-II to calculate cladding axial deformation: (a) axial PCMI, (b) trapped fuel stack, (c) fuel relocation, and (d) effective fuel thermal expansion. Comparisons of cladding axial elongation measurements from two experiments with the corresponding FRAP-T6 calculations are presented

  3. Methanofullerene elongated nanostructure formation for enhanced organic solar cells

    International Nuclear Information System (INIS)

    Reyes-Reyes, M.; Lopez-Sandoval, R.; Arenas-Alatorre, J.; Garibay-Alonso, R.; Carroll, D.L.; Lastras-Martinez, A.

    2007-01-01

    Using transmission electron microscopy (TEM) and Z-contrast imaging we have demonstrated elongated nanostructure formation of fullerene derivative [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) within an organic host through annealing. The annealing provides an enhanced mobility of the PCBM molecules and, with good initial dispersion, allows for the formation of exaggerated grain growth within the polymer host. We have assembled these nanostructures within the regioregular conjugated polymer poly(3-hexylthiophene) (P3HT). This PCBM elongated nanostructure formation maybe responsible for the very high efficiencies observed, at very low loadings of PCBM (1:0.6, polymer to PCBM), in annealed photovoltaics. Moreover, our high resolution TEM and electron energy loss spectroscopy studies clearly show that the PCBM crystals remain crystalline and are unaffected by the 200-keV electron beam

  4. Low temperature tensile properties and stress corrosion cracking resistance in the super duplex stainless steels weldments

    International Nuclear Information System (INIS)

    Lee, Jeung Woo; Sung, Jang Hyun; Lee, Sung Keun

    1998-01-01

    Low temperature tensile properties and SCC resistances of super duplex stainless steels and their weldments are investigated. Tensile strengths increase remarkably with decreasing test temperature, while elongations decrease steeply at -196 .deg. C after showing peak or constant value down to -100 .deg. C. Owing to the low tensile deformation of weld region, elongations of welded specimen decrease in comparison to those of unwelded specimen. The welded tensile specimen is fractured through weld region at -196 .deg. C due to the fact that the finely dispersed ferrite phase in the austenite matrix increases an opportunity to supply the crack propagation path through the brittle ferrite phase at low temperature. The stress corrosion cracking initiates preferentially at the surface ferrite phase of base metal region and propagates through ferrite phase. When the corrosion crack meets with the fibrously aligned austenite phase to the tensile direction, the ferrite phase around austenite continues to corrode. Eventually, fracture of the austenite phase begins without enduring the tensile load. The addition of Cu+W to the super duplex stainless steel deteriorates the SCC resistance in boiling MgCl 2 solution, possibly due to the increment of pits in the ferrite phase and reduction of N content in the austenite phase

  5. Polymer film strain gauges for measuring large elongations

    Science.gov (United States)

    Kondratov, A. P.; Zueva, A. M.; Varakin, R. S.; Taranec, I. P.; Savenkova, I. A.

    2018-02-01

    The paper shows the possibility to print polymer strain gages, microstrip lines, coplanar waveguides, and other prints for avionics using printing technology and equipment. The methods of screen and inkjet printing have been complemented by three new operations of preparing print films for application of an electrically conductive ink layer. Such additional operations make it possible to enhance the conductive ink layer adhesion to the film and to manufacture strain gages for measuring large elongations.

  6. Adiabatic compression of elongated field-reversed configurations

    Energy Technology Data Exchange (ETDEWEB)

    Spencer, R.L.; Tuszewski, M.; Linford, R.K.

    1983-06-01

    The adiabatic compression of an elongated field-reversed configuration (FRC) is computed by using a one-dimensional approximation. The one-dimensional results are checked against a two-dimensional equilibrium code. For ratios of FRC separatrix length to separatrix radius greater than about ten, the one-dimensional results are accurate within 10%. To this accuracy, the adiabatic compression of FRC's can be described by simple analytic formulas.

  7. Adiabatic compression of elongated field-reversed configurations

    International Nuclear Information System (INIS)

    Spencer, R.L.; Tuszewski, M.; Linford, R.K.

    1983-01-01

    The adiabatic compression of an elongated field-reversed configuration (FRC) is computed by using a one-dimensional approximation. The one-dimensional results are checked against a two-dimensional equilibrium code. For ratios of FRC separatrix length to separatrix radius greater than about ten, the one-dimensional results are accurate within 10%. To this accuracy, the adiabatic compression of FRC's can be described by simple analytic formulas

  8. Targeting Transcription Elongation Machinery for Breast Cancer Therapy

    Science.gov (United States)

    2017-05-01

    ABSTRACT: This project focuses on the important but under-studied role of the P-TEFb- dependent transcription elongation machinery in human breast...molecule CDK9 inhibitors can be used to halt breast cancer metastasis. 8 experimental groups to test various drug dosage and frequency regimes will...tumor cells, which are said to be ’ addicted ’ to this protein. Consistently, pharmacological inhibition of Hsp90 has demonstrated great promise in

  9. Characterization of Enzymes Involved in Fatty Acid Elongation

    Science.gov (United States)

    2007-04-11

    eukaryotes, such as MAELO (40% identity with yeast Elo2p) that elongates C16-C18 saturated and monounsaturated FAs in the filamentous fungus ...and n-6 FAs have been reported in patients suffering from hypertension [145]. Thus, several PUFA rich oil-producing organisms, including the fungus ...membrane proteome (30), a topological reporter cassette (Suc2p/His4C) was fused at the C-terminus of many membrane proteins, including Tsc13p. The

  10. Promoter binding, initiation, and elongation by bacteriophage T7 RNA polymerase. A single-molecule view of the transcription cycle.

    Science.gov (United States)

    Skinner, Gary M; Baumann, Christoph G; Quinn, Diana M; Molloy, Justin E; Hoggett, James G

    2004-01-30

    A single-molecule transcription assay has been developed that allows, for the first time, the direct observation of promoter binding, initiation, and elongation by a single RNA polymerase (RNAP) molecule in real-time. To promote DNA binding and transcription initiation, a DNA molecule tethered between two optically trapped beads was held near a third immobile surface bead sparsely coated with RNAP. By driving the optical trap holding the upstream bead with a triangular oscillation while measuring the position of both trapped beads, we observed the onset of promoter binding, promoter escape (productive initiation), and processive elongation by individual RNAP molecules. After DNA template release, transcription re-initiation on the same DNA template is possible; thus, multiple enzymatic turnovers by an individual RNAP molecule can be observed. Using bacteriophage T7 RNAP, a commonly used RNAP paradigm, we observed the association and dissociation (k(off)= 2.9 s(-1)) of T7 RNAP and promoter DNA, the transition to the elongation mode (k(for) = 0.36 s(-1)), and the processive synthesis (k(pol) = 43 nt s(-1)) and release of a gene-length RNA transcript ( approximately 1200 nt). The transition from initiation to elongation is much longer than the mean lifetime of the binary T7 RNAP-promoter DNA complex (k(off) > k(for)), identifying a rate-limiting step between promoter DNA binding and promoter escape.

  11. Brassinosteroid regulates cell elongation by modulating gibberellin metabolism in rice.

    Science.gov (United States)

    Tong, Hongning; Xiao, Yunhua; Liu, Dapu; Gao, Shaopei; Liu, Linchuan; Yin, Yanhai; Jin, Yun; Qian, Qian; Chu, Chengcai

    2014-11-01

    Brassinosteroid (BR) and gibberellin (GA) are two predominant hormones regulating plant cell elongation. A defect in either of these leads to reduced plant growth and dwarfism. However, their relationship remains unknown in rice (Oryza sativa). Here, we demonstrated that BR regulates cell elongation by modulating GA metabolism in rice. Under physiological conditions, BR promotes GA accumulation by regulating the expression of GA metabolic genes to stimulate cell elongation. BR greatly induces the expression of D18/GA3ox-2, one of the GA biosynthetic genes, leading to increased GA1 levels, the bioactive GA in rice seedlings. Consequently, both d18 and loss-of-function GA-signaling mutants have decreased BR sensitivity. When excessive active BR is applied, the hormone mostly induces GA inactivation through upregulation of the GA inactivation gene GA2ox-3 and also represses BR biosynthesis, resulting in decreased hormone levels and growth inhibition. As a feedback mechanism, GA extensively inhibits BR biosynthesis and the BR response. GA treatment decreases the enlarged leaf angles in plants with enhanced BR biosynthesis or signaling. Our results revealed a previously unknown mechanism underlying BR and GA crosstalk depending on tissues and hormone levels, which greatly advances our understanding of hormone actions in crop plants and appears much different from that in Arabidopsis thaliana. © 2014 American Society of Plant Biologists. All rights reserved.

  12. Significant enhancement by biochar of caproate production via chain elongation.

    Science.gov (United States)

    Liu, Yuhao; He, Pinjing; Shao, Liming; Zhang, Hua; Lü, Fan

    2017-08-01

    In this study, biochar was introduced into a chain elongation system to enhance the bioproduction of caproate and caprylate. The concentration of caproate increased to 21.1 g/L upon the addition of biochar, which is the highest level of caproate reported for such a system to date when ethanol was used as electron donor. The addition of biochar created a tougher system with more stable microorganism community structure for chain elongation, in which no obvious inhibition by products or substrates was observed, moreover, the lag phase was reduced 2.3-fold compared to the system without biochar. These reinforcement effect of biochar are attributed to the enhanced conductivity due to the significant enrichment of functional microorganisms via the microbial network surrounding smaller biochar particles, and via the adsorption on the rough surfaces or pores of larger particles, which facilitated electron transfer. Higher amounts of extracellular polymer substances and higher conductivity induced by biochar could contribute to the reinforcement effect in chain elongation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Analysis of cracking potential and micro-elongation of linerboard

    Directory of Open Access Journals (Sweden)

    Supattra Panthai

    2016-11-01

    Full Text Available Folding cracks of linerboards in relation to their micro-elongation and the forming conditions were studied using an industrial linerboard machine with a top former. The experiments consisted of the study of various forming conditions by manipulating the jet/wire speed ratio to produce linerboard with differences in fiber structures that were related to the cracked and uncracked products. The results showed that changes to the jet/wire speed ratio of about 0.01–0.02 to improve the tested folding endurance in the machine direction potentially produced folding cracks in the linerboard, which indicated an ambiguous interpretation of the foldability tests. The delaminated cracked layers were found to have a high folding endurance and tensile strength, while the decrease in the micro-elongation formulated in this study was found to be related to cracking. A lower micro-elongation of about 350–500 μm/N·g was found in a range of products with folding cracks.

  14. Photo-oxidation of LDPE: Effects on elongational viscosity

    Science.gov (United States)

    Rolón-Garrido, Víctor H.; Wagner, Manfred H.

    2013-04-01

    Sheets of low-density polyethylene (LDPE) were photo-oxidatively treated at room temperature, and subsequently characterized rheologically in the melt state by shear and uniaxial extensional experiments. For photo-oxidation, a xenon lamp was used to irradiate the samples for times between 1 day and 6 weeks. Linear-viscoelastic characterization was performed in a temperature range of 130 to 220°C to obtain the master curve at 170°C, the reference temperature at which the elongational viscosities were measured. Linear viscoelasticity is increasingly affected by increasing photo-oxidation due to crosslinking of LDPE, as corroborated by an increasing gel fraction as determined by a solvent extraction method. The elongational measurements reveal a strong enhancement of strain hardening until a saturation level is achieved. The elongational data are analyzed in the frame work of two constitutive equations, the rubber-like liquid and the molecular stress function models. Within the experimental window, time-deformation separability is confirmed for all samples, independent of the degree of photo-oxidation.

  15. Characterization of microstructure and texture across dissimilar super duplex/austenitic stainless steel weldment joint by super duplex filler metal

    Energy Technology Data Exchange (ETDEWEB)

    Eghlimi, Abbas, E-mail: a.eghlimi@ma.iut.ac.ir [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Shamanian, Morteza [Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Eskandarian, Masoomeh [Department of Materials Engineering, Shiraz University, Shiraz 71348-51154 (Iran, Islamic Republic of); Zabolian, Azam [Department of Natural Resources, Isfahan University of Technology, Isfahan 84156-83111 (Iran, Islamic Republic of); Szpunar, Jerzy A. [Department of Mechanical Engineering, University of Saskatchewan, Saskatoon SK S7N 5A9 (Canada)

    2015-08-15

    In the present paper, microstructural changes across an as-welded dissimilar austenitic/duplex stainless steel couple welded by a super duplex stainless steel filler metal using gas tungsten arc welding process is characterized with optical microscopy and electron back-scattered diffraction techniques. Accordingly, variations of microstructure, texture, and grain boundary character distribution of base metals, heat affected zones, and weld metal were investigated. The results showed that the weld metal, which was composed of Widmanstätten austenite side-plates and allotriomorphic grain boundary austenite morphologies, had the weakest texture and was dominated by low angle boundaries. The welding process increased the ferrite content but decreased the texture intensity at the heat affected zone of the super duplex stainless steel base metal. In addition, through partial ferritization, it changed the morphology of elongated grains of the rolled microstructure to twinned partially transformed austenite plateaus scattered between ferrite textured colonies. However, the texture of the austenitic stainless steel heat affected zone was strengthened via encouraging recrystallization and formation of annealing twins. At both interfaces, an increase in the special character coincident site lattice boundaries of the primary phase as well as a strong texture with <100> orientation, mainly of Goss component, was observed. - Graphical abstract: Display Omitted - Highlights: • Weld metal showed local orientation at microscale but random texture at macroscale. • Intensification of <100> orientated grains was observed adjacent to the fusion lines. • The austenite texture was weaker than that of the ferrite in all duplex regions. • Welding caused twinned partially transformed austenites to form at SDSS HAZ. • At both interfaces, the ratio of special CSL boundaries of the primary phase increased.

  16. Super resolution for astronomical observations

    Science.gov (United States)

    Li, Zhan; Peng, Qingyu; Bhanu, Bir; Zhang, Qingfeng; He, Haifeng

    2018-05-01

    In order to obtain detailed information from multiple telescope observations a general blind super-resolution (SR) reconstruction approach for astronomical images is proposed in this paper. A pixel-reliability-based SR reconstruction algorithm is described and implemented, where the developed process incorporates flat field correction, automatic star searching and centering, iterative star matching, and sub-pixel image registration. Images captured by the 1-m telescope at Yunnan Observatory are used to test the proposed technique. The results of these experiments indicate that, following SR reconstruction, faint stars are more distinct, bright stars have sharper profiles, and the backgrounds have higher details; thus these results benefit from the high-precision star centering and image registration provided by the developed method. Application of the proposed approach not only provides more opportunities for new discoveries from astronomical image sequences, but will also contribute to enhancing the capabilities of most spatial or ground-based telescopes.

  17. q-deformations of noncompact Lie (super-) algebras: The examples of q-deformed Lorentz, Weyl, Poincare' and (super-) conformal algebras

    International Nuclear Information System (INIS)

    Dobrev, V.K.

    1992-01-01

    We review and explain a canonical procedure for the q-deformation of the real forms G of complex Lie (super-) algebras associated with (generalized) Cartan matrices. Our procedure gives different q-deformations for the non-conjugate Cartan subalgebras of G. We give several in detail the q-deformed Lorentz and conformal (super-) algebras. The q-deformed conformal algebra contains as a subalgebra a q-deformed Poincare algebra and as Hopf subalgebras two conjugate 11-generator q-deformed Weyl algebras. The q-deformed Lorentz algebra in Hopf subalgebra of both Weyl algebras. (author). 24 refs

  18. Status report of BL08 superHRPD

    International Nuclear Information System (INIS)

    Torii, Shuki

    2010-01-01

    At the end of May in 2008, the first neutron was produced successfully from a spallation neutron source in Japan Proton Accelerator Research Complex (J-PARC). High resolution Bragg reflections were obtained using the Sirius diffractometer chamber at Super High Resolution Powder Diffractometer (SuperHARD) beam line at Materials and Life Science Experimental Facility (MLF). We started up quickly by using the existing Sirius chamber, and had succeeded in achieving resolution as Δd/d=0.035 %, the best among all the entire neutron powder diffractometers in the world. About 300 detectors had been installed in the backward detector bank, and several standard samples had been measured. Simultaneously, we were carrying out basic study to design and construct a new SuperHRPD chamber, and the Sirius chamber had been exchanged for new one in summer of 2009. In the design of a new chamber, a detector solid angle is increased, d-range/Q-range is expanded, and also has options of high-intensity mode and high-resolution mode with incident collimations. (author)

  19. Characteristics of elongated and ruptured anterior cruciate ligament grafts: An analysis of 21 consecutive revision cases

    Directory of Open Access Journals (Sweden)

    Kohei Iio

    2017-04-01

    Conclusion: The location of the original femoral tunnel was more proximal in patients with elongated grafts than in those with ruptured grafts. Different bone tunnel position from native ACL might lead to graft elongation.

  20. SuperB Progress Report for Physics

    Energy Technology Data Exchange (ETDEWEB)

    O' Leary, B.; /Aachen, Tech. Hochsch.; Matias, J.; Ramon, M.; /Barcelona, IFAE; Pous, E.; /Barcelona U.; De Fazio, F.; Palano, A.; /INFN, Bari; Eigen, G.; /Bergen U.; Asgeirsson, D.; /British Columbia U.; Cheng, C.H.; Chivukula, A.; Echenard, B.; Hitlin, D.G.; Porter, F.; Rakitin, A.; /Caltech; Heinemeyer, S.; /Cantabria Inst. of Phys.; McElrath, B.; /CERN; Andreassen, R.; Meadows, B.; Sokoloff, M.; /Cincinnati U.; Blanke, M.; /Cornell U., Phys. Dept.; Lesiak, T.; /Cracow, INP /DESY /Zurich, ETH /INFN, Ferrara /Frascati /INFN, Genoa /Glasgow U. /Indiana U. /Mainz U., Inst. Phys. /Karlsruhe, Inst. Technol. /KEK, Tsukuba /LBL, Berkeley /UC, Berkeley /Lisbon, IST /Ljubljana U. /Madrid, Autonoma U. /Maryland U. /MIT /INFN, Milan /McGill U. /Munich, Tech. U. /Notre Dame U. /PNL, Richland /INFN, Padua /Paris U., VI-VII /Orsay, LAL /Orsay, LPT /INFN, Pavia /INFN, Perugia /INFN, Pisa /Queen Mary, U. of London /Regensburg U. /Republica U., Montevideo /Frascati /INFN, Rome /INFN, Rome /INFN, Rome /Rutherford /Sassari U. /Siegen U. /SLAC /Southern Methodist U. /Tel Aviv U. /Tohoku U. /INFN, Turin /INFN, Trieste /Uppsala U. /Valencia U., IFIC /Victoria U. /Wayne State U. /Wisconsin U., Madison

    2012-02-14

    SuperB is a high luminosity e{sup +}e{sup -} collider that will be able to indirectly probe new physics at energy scales far beyond the reach of any man made accelerator planned or in existence. Just as detailed understanding of the Standard Model of particle physics was developed from stringent constraints imposed by flavour changing processes between quarks, the detailed structure of any new physics is severely constrained by flavour processes. In order to elucidate this structure it is necessary to perform a number of complementary studies of a set of golden channels. With these measurements in hand, the pattern of deviations from the Standard Model behavior can be used as a test of the structure of new physics. If new physics is found at the LHC, then the many golden measurements from SuperB will help decode the subtle nature of the new physics. However if no new particles are found at the LHC, SuperB will be able to search for new physics at energy scales up to 10-100 TeV. In either scenario, flavour physics measurements that can be made at SuperB play a pivotal role in understanding the nature of physics beyond the Standard Model. Examples for using the interplay between measurements to discriminate New Physics models are discussed in this document. SuperB is a Super Flavour Factory, in addition to studying large samples of B{sub u,d,s}, D and {tau} decays, SuperB has a broad physics programme that includes spectroscopy both in terms of the Standard Model and exotica, and precision measurements of sin{sup 2} {theta}{sub W}. In addition to performing CP violation measurements at the {Upsilon}(4S) and {phi}(3770), SuperB will test CPT in these systems, and lepton universality in a number of different processes. The multitude of rare decay measurements possible at SuperB can be used to constrain scenarios of physics beyond the Standard Model. In terms of other precision tests of the Standard Model, this experiment will be able to perform precision over

  1. SuperB Progress Report for Physics

    International Nuclear Information System (INIS)

    O'Leary, B.; Matias, J.; Ramon, M.

    2012-01-01

    SuperB is a high luminosity e + e - collider that will be able to indirectly probe new physics at energy scales far beyond the reach of any man made accelerator planned or in existence. Just as detailed understanding of the Standard Model of particle physics was developed from stringent constraints imposed by flavour changing processes between quarks, the detailed structure of any new physics is severely constrained by flavour processes. In order to elucidate this structure it is necessary to perform a number of complementary studies of a set of golden channels. With these measurements in hand, the pattern of deviations from the Standard Model behavior can be used as a test of the structure of new physics. If new physics is found at the LHC, then the many golden measurements from SuperB will help decode the subtle nature of the new physics. However if no new particles are found at the LHC, SuperB will be able to search for new physics at energy scales up to 10-100 TeV. In either scenario, flavour physics measurements that can be made at SuperB play a pivotal role in understanding the nature of physics beyond the Standard Model. Examples for using the interplay between measurements to discriminate New Physics models are discussed in this document. SuperB is a Super Flavour Factory, in addition to studying large samples of B u,d,s , D and τ decays, SuperB has a broad physics programme that includes spectroscopy both in terms of the Standard Model and exotica, and precision measurements of sin 2 θ W . In addition to performing CP violation measurements at the Υ(4S) and φ(3770), SuperB will test CPT in these systems, and lepton universality in a number of different processes. The multitude of rare decay measurements possible at SuperB can be used to constrain scenarios of physics beyond the Standard Model. In terms of other precision tests of the Standard Model, this experiment will be able to perform precision over-constraints of the unitarity triangle through

  2. Super-radiance in Nuclear Physics

    International Nuclear Information System (INIS)

    Auerbach, N

    2015-01-01

    The theory of the super-radiant mechanism as applied to various phenomena in nuclear physics is presented. The connection between super-radiance and the notion of doorway is presented. The statistics of resonance widths in a many-body Fermi system with open channels is discussed. Depending on the strength of the coupling to the continuum such systems show deviations from the standard Porter-Thomas distribution. The deviations result from the process of increasing interaction of the intrinsic states via the common decay channels. In the limit of very strong coupling this leads to super-radiance. (paper)

  3. A non-catalytic N-terminal domain negatively influences the nucleotide exchange activity of translation elongation factor 1Bα.

    Science.gov (United States)

    Trosiuk, Tetiana V; Shalak, Vyacheslav F; Szczepanowski, Roman H; Negrutskii, Boris S; El'skaya, Anna V

    2016-02-01

    Eukaryotic translation elongation factor 1Bα (eEF1Bα) is a functional homolog of the bacterial factor EF-Ts, and is a component of the macromolecular eEF1B complex. eEF1Bα functions as a catalyst of guanine nucleotide exchange on translation elongation factor 1A (eEF1A). The C-terminal domain of eEF1Bα is necessary and sufficient for its catalytic activity, whereas the N-terminal domain interacts with eukaryotic translation elongation factor 1Bγ (eEF1Bγ) to form a tight complex. However, eEF1Bγ has been shown to enhance the catalytic activity of eEF1Bα attributed to the C-terminal domain of eEF1Bα. This suggests that the N-terminal domain of eEF1Bα may in some way influence the guanine nucleotide exchange process. We have shown that full-length recombinant eEF1Bα and its truncated forms are non-globular proteins with elongated shapes. Truncation of the N-terminal domain of eEF1Bα, which is dispensable for catalytic activity, resulted in acceleration of the rate of guanine nucleotide exchange on eEF1A compared to full-length eEF1Bα. A similar effect on the catalytic activity of eEF1Bα was observed after its interaction with eEF1Bγ. We suggest that the non-catalytic N-terminal domain of eEF1Bα may interfere with eEF1A binding to the C-terminal catalytic domain, resulting in a decrease in the overall rate of the guanine nucleotide exchange reaction. Formation of a tight complex between the eEF1Bγ and eEF1Bα N-terminal domains abolishes this inhibitory effect. © 2015 FEBS.

  4. QTL analysis of internode elongation in response to gibberellin in deepwater rice

    OpenAIRE

    Nagai, Keisuke; Kondo, Yuma; Kitaoka, Takuya; Noda, Tomonori; Kuroha, Takeshi; Angeles-Shim, Rosalyn B.; Yasui, Hideshi; Yoshimura, Atsushi; Ashikari, Motoyuki

    2014-01-01

    Gibberellin (GA) is a plant hormone that has important roles in numerous plant developmental phases. Rice plants known as deepwater rice respond to flooding by elongating their internodes to avoid anoxia. Previous studies reported that GA is essential for internode elongation in deepwater rice. Quantitative trait locus (QTL) analyses identified QTLs regulating internode elongation in response to deepwater conditions. However, the interaction between internode elongation and regulators of GA s...

  5. Methanol as an alternative electron donor in chain elongation for butyrate and caproate formation

    OpenAIRE

    Chen, W.S.; Ye, Y.; Steinbusch, K.J.J.; Strik, D.P.B.T.B.; Buisman, C.J.N.

    2016-01-01

    Chain elongation is an emerging mixed culture biotechnology converting acetate into valuable biochemicals by using ethanol as an external electron donor. In this study we proposed to test another potential electron donor, methanol, in chain elongation. Methanol can be produced through the thermochemical conversion of lignocellulosic biowaste. Use of methanol in chain elongation integrates the lignocellulosic feedstocks and the thermochemical platform technologies into chain elongation. After ...

  6. Super-Calogero-Moser-Sutherland systems and free super-oscillators: a mapping

    International Nuclear Information System (INIS)

    Ghosh, Pijush K.

    2001-01-01

    We show that the supersymmetric rational Calogero-Moser-Sutherland (CMS) model of A N+1 -type is equivalent to a set of free super-oscillators, through a similarity transformation. We prescribe methods to construct the complete eigenspectrum and the associated eigenfunctions, both in supersymmetry-preserving as well as supersymmetry-breaking phases, from the free super-oscillator basis. Further we show that a wide class of super-Hamiltonians realizing dynamical OSp(2 vertical bar 2) supersymmetry, which also includes all types of rational super-CMS as a small subset, are equivalent to free super-oscillators. We study BC N+1 -type super-CMS model in some detail to understand the subtleties involved in this method

  7. BolA inhibits cell elongation and regulates MreB expression levels.

    Science.gov (United States)

    Freire, Patrick; Moreira, Ricardo Neves; Arraiano, Cecília Maria

    2009-02-06

    The morphogene bolA is a general stress response gene in Escherichia coli that induces a round morphology when overexpressed. Results presented in this report show that increased BolA levels can inhibit cell elongation mechanisms. MreB polymerization is crucial for the bacterial cell cytoskeleton, and this protein is essential for the maintenance of a cellular rod shape. In this report, we demonstrate that bolA overexpression affects the architecture of MreB filaments. An increase in BolA leads to a significant reduction in MreB protein levels and mreB transcripts. BolA affects the mreBCD operon in vivo at the level of transcription. Furthermore, our results show that BolA is a new transcriptional repressor of MreB. The alterations in cell morphology induced by bolA seem to be mediated by a complex pathway that integrates PBP5, PBP6, MreB, and probably other regulators of cell morphology/elongation.

  8. Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.

    Science.gov (United States)

    Brown, Nicholas G; VanderLinden, Ryan; Watson, Edmond R; Weissmann, Florian; Ordureau, Alban; Wu, Kuen-Phon; Zhang, Wei; Yu, Shanshan; Mercredi, Peter Y; Harrison, Joseph S; Davidson, Iain F; Qiao, Renping; Lu, Ying; Dube, Prakash; Brunner, Michael R; Grace, Christy R R; Miller, Darcie J; Haselbach, David; Jarvis, Marc A; Yamaguchi, Masaya; Yanishevski, David; Petzold, Georg; Sidhu, Sachdev S; Kuhlman, Brian; Kirschner, Marc W; Harper, J Wade; Peters, Jan-Michael; Stark, Holger; Schulman, Brenda A

    2016-06-02

    Protein ubiquitination involves E1, E2, and E3 trienzyme cascades. E2 and RING E3 enzymes often collaborate to first prime a substrate with a single ubiquitin (UB) and then achieve different forms of polyubiquitination: multiubiquitination of several sites and elongation of linkage-specific UB chains. Here, cryo-EM and biochemistry show that the human E3 anaphase-promoting complex/cyclosome (APC/C) and its two partner E2s, UBE2C (aka UBCH10) and UBE2S, adopt specialized catalytic architectures for these two distinct forms of polyubiquitination. The APC/C RING constrains UBE2C proximal to a substrate and simultaneously binds a substrate-linked UB to drive processive multiubiquitination. Alternatively, during UB chain elongation, the RING does not bind UBE2S but rather lures an evolving substrate-linked UB to UBE2S positioned through a cullin interaction to generate a Lys11-linked chain. Our findings define mechanisms of APC/C regulation, and establish principles by which specialized E3-E2-substrate-UB architectures control different forms of polyubiquitination. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Super rigid nature of super-deformed bands

    International Nuclear Information System (INIS)

    Sharma, Neha; Mittal, H.M.; Jain, A.K.

    2012-01-01

    The phenomenon of high-spin super-deformation represents one of the most remarkable discoveries in nuclear physics. A large number of SD bands have been observed in A = 60, 80, 130, 150, 190 mass regions. The cascades of SD bands are known to be connected by electric quadruple E2 transitions. Because of absence of linking transitions between superdeformed (SD) and normal deformed (ND) levels, the spin assignments of most of these bands carry a minimum uncertainty ≈ 1-2ħ. It was found in an analysis of SD bands in the context of semi classical approach that moment of inertia comes close to the rigid body value in most of the cases. Lack of knowledge of spins has led to an emphasis on the study of dynamical moment of inertia of SD bands and systematic of kinematic moment of inertia has not been examined so far. In this paper, we extract the band moment of inertia J 0 and softness parameter (σ) of all the SD bands corresponding to axes ratio (x) = 1.5 and present their systematic

  10. A superparticle on the 'super' Poincare upper half plane

    International Nuclear Information System (INIS)

    Uehara, S.; Yasui, Yukinora

    1988-01-01

    A non-relativistic superparticle moving freely on the 'super' Poincare upper half plane is investigated. The lagrangian is invariant under the super Moebius transformations SPL (2, R), so that it can be projected into the lagrangian on the super Riemann surface. The quantum hamiltonian becomes the 'super' Laplace-Beltrami operator in the curved superspace. (orig.)

  11. Superparticle on the 'super' Poincare upper half plane

    Energy Technology Data Exchange (ETDEWEB)

    Uehara, S; Yasui, Yukinora

    1988-03-17

    A non-relativistic superparticle moving freely on the 'super' Poincare upper half plane is investigated. The lagrangian is invariant under the super Moebius transformations SPL (2, R), so that it can be projected into the lagrangian on the super Riemann surface. The quantum hamiltonian becomes the 'super' Laplace-Beltrami operator in the curved superspace.

  12. Fruiting branch K+ level affects cotton fibre elongation through osmoregulation

    Directory of Open Access Journals (Sweden)

    Jiashuo eYang

    2016-01-01

    Full Text Available Potassium (K deficiency in cotton plants results in reduced fibre length. As one of the primary osmotica, K+ contributes to an increase in cell turgor pressure during fibre elongation. Therefore, it is hypothesized that fibre length is affected by K deficiency through an osmotic pathway, so in 2012 and 2013, an experiment was conducted to test this hypothesis by imposing three potassium supply regimes (0, 125, 250 kg K ha-1 on a low-K-sensitive cultivar, Siza 3, and a low-K-tolerant cultivar, Simian 3. We found that fibres were longer in the later season bolls than in the earlier ones in cotton plants grown under normal growth conditions, but later season bolls showed a greater sensitivity to low-K stress, especially the low-K sensitive genotype. We also found that the maximum velocity of fibre elongation (Vmax is the parameter that best reflects the change in fibre elongation under K deficiency. This parameter mostly depends on cell turgor, so the content of the osmotically active solutes was analysed accordingly. Statistical analysis showed that K+ was the major osmotic factor affecting fibre length, and malate was likely facilitating K+ accumulation into fibres, which enabled the low-K-tolerant genotype to cope with low-K stress. Moreover, the low-K-tolerant genotype tended to have greater K+ absorptive capacities in the upper fruiting branches. Based on our findings, we suggest a fertilization scheme for Gossypium hirsutum that adds extra potash fertilizer or distributes it during the development of late season bolls to mitigate K deficiency in the second half of the growth season and to enhance fibre length in late season bolls.

  13. Experiments at high elongations in DIII-D

    International Nuclear Information System (INIS)

    Lazarus, E.A.; Turnbull, A.D.; Kellman, A.G.; Ferron, J.R.; Helton, F.J.; Lao, L.L.; Leuer, J.A.; Strait, E.J.; Taylor, T.S.

    1990-06-01

    In this paper we discuss the limitation to elongation observed in D-shaped plasmas in the DIII-D tokamak. We find that as the triangularity is increased and ell i is decreased that the n = 0 mode takes on an increasingly non-rigid character. Our analysis shows two aspects of the behavior; first, an increasing variation of the m/n = 1/0 component across flux surfaces and second, an increase in the relative amplitude of a m/n = 3/0 component which couples to the m/n = 1/0 component and further destabilizes the mode

  14. Time Dependent and Steady Uni-axial Elongational Viscosity

    DEFF Research Database (Denmark)

    Nielsen, Jens K.; Rasmussen, Henrik Koblitz; Hassager, Ole

    2005-01-01

    Here we present measurements of transient and steady uni-axial elongational viscosity, using the Filament Stretching Rheometer1 or FSR1 (see Fig. 1) of the following melts: Four narrow MMD polystyrene (PS) samples with weight-average molar mass Mw in the range of 50k to 390k. Three different bi......-disperse samples, mixed from the narrow MMD PS. Two low-density polyethylene (LDPE) melts (Lupolen 1840D and 3020D). A steady-state viscosity was kept for 1-2.5 Hencky strain units in all measurements....

  15. Experimental study of charmed baryons at SuperLEAR

    International Nuclear Information System (INIS)

    Poulet, M.

    1991-01-01

    The possibility to study and detect the charmed baryons at SuperLEAR was examined. It was found that it is possible only if the search is restricted to the single charm baryons Λ c , Σ c , Ξ c . The experimental approach requires high luminosity and some complexity of the detection system. It has to be considered as a second generation jet target experiment in a range of p-bar momentum from 8 to 15 GeV/c. (R.P.) 12 refs., 2 figs

  16. W∞ gravity and super-W∞ gravity

    International Nuclear Information System (INIS)

    Bergshoeff, E.; Pope, C.N.; Shen, X.; Sezgin, E.; Romans, L.J.

    1991-01-01

    In this paper, the authors construct gauge theories of the W ∞ algebra and its super-extension, and discuss their relation to earlier results for the gauging of the classical contraction to the w ∞ algebra

  17. Translation elongation factor 1A facilitates the assembly of the tombusvirus replicase and stimulates minus-strand synthesis.

    OpenAIRE

    Zhenghe Li; Judit Pogany; Steven Tupman; Anthony M Esposito; Terri Goss Kinzy; Peter D Nagy

    2010-01-01

    Replication of plus-strand RNA viruses depends on host factors that are recruited into viral replicase complexes. Previous studies showed that eukaryotic translation elongation factor (eEF1A) is one of the resident host proteins in the highly purified tombusvirus replicase complex. Using a random library of eEF1A mutants, we identified one mutant that decreased and three mutants that increased Tomato bushy stunt virus (TBSV) replication in a yeast model host. Additional in vitro assays with w...

  18. Charm Physics at SuperB

    International Nuclear Information System (INIS)

    Meadows, Brian; Bevan, Adrian

    2010-01-01

    The study of Charm Decays at SuperB provide unique opportunities to understand the Standard Model and constrain new physics, both at the Y(4S), and at charm threshold. We discuss the physics potential of such measurements from the proposed SuperB experiment with 75 ab -1 of data at the Y(4S) and a subsequent run dedicated to exploiting quantum correlations at the charm threshold. (author)

  19. The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress

    DEFF Research Database (Denmark)

    Clausing, Emanuel; Mayer, Andreas; Chanarat, Sittinan

    2010-01-01

    Multiple DNA-associated processes such as DNA repair, replication, and recombination are crucial for the maintenance of genome integrity. Here, we show a novel interaction between the transcription elongation factor Bur1-Bur2 and replication protein A (RPA), the eukaryotic single-stranded DNA......-binding protein with functions in DNA repair, recombination, and replication. Bur1 interacted via its C-terminal domain with RPA, and bur1-¿C mutants showed a deregulated DNA damage response accompanied by increased sensitivity to DNA damage and replication stress as well as increased levels of persisting Rad52...... foci. Interestingly, the DNA damage sensitivity of an rfa1 mutant was suppressed by bur1 mutation, further underscoring a functional link between these two protein complexes. The transcription elongation factor Bur1-Bur2 interacts with RPA and maintains genome integrity during DNA replication stress....

  20. SuperKEKB Vacuum System

    CERN Document Server

    Shibata, K

    2013-01-01

    SuperKEKB, which is an upgrade of the KEKB Bfactory (KEKB), is a next-generation high-luminosity electron-positron collider. Its design luminosity is 8.0× 10$^{35}$ cm$^{-2}s^{-1}$, which is about 40 times than the KEKB’s record. To achieve this challenging goal, bunches of both beams are squeezed extremely to the nanometer scale and the beam currents are doubled. To realize this, many upgrades must be performed including the replacement of beam pipes mainly in the positron ring (LER). The beam pipes in the LER arc section are being replaced with new aluminium-alloy pipes with antechambers to cope with the electron cloud issue and heating problem. Additionally, several types of countermeasures will be adopted in the LER to deal with the electron cloud issues. In the wiggler section, electrons will be attracted by the clearing electrode, which is mounted on the inner surface of the beam pipe. On the other hand, in the bending magnet, the effective secondary electron yield (SEY) will be structurally reduced ...

  1. Studies of the Super VELO

    CERN Document Server

    AUTHOR|(CDS)2156302

    2016-01-01

    The Super VELO is the Run 5 upgrade of the VeloPix detector of the LHCb experiment. Its most challenging task is to cope with a luminosity increase of the factor 10. This study examines the potential physics performance of a detector based on the VeloPix design at high luminosity conditions. It is found that an unmodified VeloPix detector shows poor performance when exposed to 10x design luminosity, most gravely high ghost rates of 40 %. When applying basic assumptions about material changes such as cutting the silicon thickness by half and removing the RF foil, the ghost rate drops by 20 %. When using thin silicon and re-optimizing the tracking algorithm, the ghost rate can even be reduced by 60 %. Applying the additional modification of a pixel area size four times smaller, the ghost rate drops by 88 % and the IP resolution improves. Finally, in a dream scenario with thin silicon, smaller pixels and no RF foil, big gains in resolution and a ghost rate of less than 4 % can be achieved.

  2. The tristan super light facility

    International Nuclear Information System (INIS)

    1992-12-01

    The Photon Factory and its user group have achieved excellent scientific results since its commissioning in 1982, ranging from material science to medical application, by using the synchrotron radiation at the 2.5 GeV PF storage ring, and since 1986, further at the 6.5 GeV Tristan accumulation ring which provides brilliant photons in high energy region. Efforts are exerted currently at National Laboratory for High Energy Physics for the extensive research and development works to study the feasibility of the Tristan e + e - collider main ring to be utilized as an extremely intense and highly advanced light source, which is called Tristan super light facility. What kinds of the application are expected for such highly brilliant source and their scientific significance should be clarified. This design report is an outcome by the joint work of in-house staffs and outside users, and it would serve as an excellent guide for the future studies on a next generation synchrotron radiation light source. The conversion plan of Tristan, the basic design of insertion devices, coherent X-ray sources, beam lines, instrumentation and others are reported. (K.I.)

  3. SuperKEKB Vacuum System

    International Nuclear Information System (INIS)

    Shibata, K

    2013-01-01

    SuperKEKB, which is an upgrade of the KEKB Bfactory (KEKB), is a next-generation high-luminosity electron-positron collider. Its design luminosity is 8.0 × 10 35 cm −2 s −1 , which is about 40 times than the KEKB’s record. To achieve this challenging goal, bunches of both beams are squeezed extremely to the nanometer scale and the beam currents are doubled. To realize this, many upgrades must be performed including the replacement of beam pipes mainly in the positron ring (LER). The beam pipes in the LER arc section are being replaced with new aluminium-alloy pipes with antechambers to cope with the electron cloud issue and heating problem. Additionally, several types of countermeasures will be adopted in the LER to deal with the electron cloud issues. In the wiggler section, electrons will be attracted by the clearing electrode, which is mounted on the inner surface of the beam pipe. On the other hand, in the bending magnet, the effective secondary electron yield (SEY) will be structurally reduced by the groove surface with a TiN coating. In the drift space, the electron cloud will be mitigated by the TiN coating and a conventional solenoid field. (author)

  4. A novel super-resolution camera model

    Science.gov (United States)

    Shao, Xiaopeng; Wang, Yi; Xu, Jie; Wang, Lin; Liu, Fei; Luo, Qiuhua; Chen, Xiaodong; Bi, Xiangli

    2015-05-01

    Aiming to realize super resolution(SR) to single image and video reconstruction, a super resolution camera model is proposed for the problem that the resolution of the images obtained by traditional cameras behave comparatively low. To achieve this function we put a certain driving device such as piezoelectric ceramics in the camera. By controlling the driving device, a set of continuous low resolution(LR) images can be obtained and stored instantaneity, which reflect the randomness of the displacements and the real-time performance of the storage very well. The low resolution image sequences have different redundant information and some particular priori information, thus it is possible to restore super resolution image factually and effectively. The sample method is used to derive the reconstruction principle of super resolution, which analyzes the possible improvement degree of the resolution in theory. The super resolution algorithm based on learning is used to reconstruct single image and the variational Bayesian algorithm is simulated to reconstruct the low resolution images with random displacements, which models the unknown high resolution image, motion parameters and unknown model parameters in one hierarchical Bayesian framework. Utilizing sub-pixel registration method, a super resolution image of the scene can be reconstructed. The results of 16 images reconstruction show that this camera model can increase the image resolution to 2 times, obtaining images with higher resolution in currently available hardware levels.

  5. Developing relationships between environmental variables and stem elongation in chrysanthemum

    International Nuclear Information System (INIS)

    Jacobson, B.M.; Willits, D.H.

    1998-01-01

    The main objective of this research was to model the relationships between the environmental variables and stem elongation in chrysanthemum with the end-goal of producing a model appropriate for use in the dynamic control of a greenhouse environment. The plants used were Dendranthema grandiflora cv. 'Spice'. The model developed uses Richards' growth equation (Richards, 1969) as its base. Adaptations were made to Richards' growth equation to explicitly include the effects of day and night temperature, daily PPF (photosynthetic photon flux), end-of-day red to far-red ratio, and position of the internode on the stem on internode elongation. The model fit the observed final length data reasonably well (R2 = 0.89). Sensitivity analyses indicated that increasing day temperature had a positive effect on internode length while increasing night temperature had a negative effect, with night temperature having a considerably larger effect than the effect of day temperature. The analyses suggests that both high and low end-of-day red to far-red ratios will produce increased lengths and that increasing daily PPF will produce decreased lengths. The analyses also suggests that internodes which develop later on the plant will generally have larger lengths as reflected by the measured data

  6. Enhanced photoanisotropic response in azopolymer doped with elongated goethite nanoparticles

    International Nuclear Information System (INIS)

    Nedelchev, L; Nazarova, D; Berberova, N; Mateev, G; Kostadinova, D; Mariño-Fernández, R; Salgueiriño, V; Schmool, D

    2016-01-01

    We present a study of the photoinduced birefringence in nanocomposite films of an azopolymer (PAZO) doped with goethite (a-FeOOH, a characteristic antiferromagnetic material) nanoparticles (NPs). The NPs had an elongated shape with a size 15×150 nm, i.e., a ratio of 1:10. Samples were prepared with different concentrations of the NPs in the azopolymer varying from 0% (undoped azopolymer film) to 15 wt %. An unusual dependence of the birefringence on the concentration was observed - two peaks of enhancement at 1 % and at 10 % concentration. Our previous studies on ZnO and SiO 2 NP have indicated only one peak of increase at low concentrations - 0.5 wt % and 2 wt %, respectively. This effect could be related to the elongated shape of the nanoparticles and the presence of two characteristic NPs sizes - 15 and 150 nm. Moreover, the birefringence increase for the samples with 10 wt % NPs concentration (compared with the non-doped samples) was rather significant - nearly 70%. (paper)

  7. Doc toxin is a kinase that inactivates elongation factor Tu.

    Science.gov (United States)

    Cruz, Jonathan W; Rothenbacher, Francesca P; Maehigashi, Tatsuya; Lane, William S; Dunham, Christine M; Woychik, Nancy A

    2014-03-14

    The Doc toxin from bacteriophage P1 (of the phd-doc toxin-antitoxin system) has served as a model for the family of Doc toxins, many of which are harbored in the genomes of pathogens. We have shown previously that the mode of action of this toxin is distinct from the majority derived from toxin-antitoxin systems: it does not cleave RNA; in fact P1 Doc expression leads to mRNA stabilization. However, the molecular triggers that lead to translation arrest are not understood. The presence of a Fic domain, albeit slightly altered in length and at the catalytic site, provided a clue to the mechanism of P1 Doc action, as most proteins with this conserved domain inactivate GTPases through addition of an adenylyl group (also referred to as AMPylation). We demonstrated that P1 Doc added a single phosphate group to the essential translation elongation factor and GTPase, elongation factor (EF)-Tu. The phosphorylation site was at a highly conserved threonine, Thr-382, which was blocked when EF-Tu was treated with the antibiotic kirromycin. Therefore, we have established that Fic domain proteins can function as kinases. This distinct enzymatic activity exhibited by P1 Doc also solves the mystery of the degenerate Fic motif unique to the Doc family of toxins. Moreover, we have established that all characterized Fic domain proteins, even those that phosphorylate, target pivotal GTPases for inactivation through a post-translational modification at a single functionally critical acceptor site.

  8. Doc Toxin Is a Kinase That Inactivates Elongation Factor Tu*

    Science.gov (United States)

    Cruz, Jonathan W.; Rothenbacher, Francesca P.; Maehigashi, Tatsuya; Lane, William S.; Dunham, Christine M.; Woychik, Nancy A.

    2014-01-01

    The Doc toxin from bacteriophage P1 (of the phd-doc toxin-antitoxin system) has served as a model for the family of Doc toxins, many of which are harbored in the genomes of pathogens. We have shown previously that the mode of action of this toxin is distinct from the majority derived from toxin-antitoxin systems: it does not cleave RNA; in fact P1 Doc expression leads to mRNA stabilization. However, the molecular triggers that lead to translation arrest are not understood. The presence of a Fic domain, albeit slightly altered in length and at the catalytic site, provided a clue to the mechanism of P1 Doc action, as most proteins with this conserved domain inactivate GTPases through addition of an adenylyl group (also referred to as AMPylation). We demonstrated that P1 Doc added a single phosphate group to the essential translation elongation factor and GTPase, elongation factor (EF)-Tu. The phosphorylation site was at a highly conserved threonine, Thr-382, which was blocked when EF-Tu was treated with the antibiotic kirromycin. Therefore, we have established that Fic domain proteins can function as kinases. This distinct enzymatic activity exhibited by P1 Doc also solves the mystery of the degenerate Fic motif unique to the Doc family of toxins. Moreover, we have established that all characterized Fic domain proteins, even those that phosphorylate, target pivotal GTPases for inactivation through a post-translational modification at a single functionally critical acceptor site. PMID:24448800

  9. Device for measuring hole elongation in a bolted joint

    Science.gov (United States)

    Wichorek, Gregory R. (Inventor)

    1987-01-01

    A device to determine the operable failure mode of mechanically fastened lightweight composite joints by measuring the hole elongation of a bolted joint is disclosed. The double-lap joint test apparatus comprises a stud, a test specimen having a hole, two load transfer plates, and linear displacement measuring instruments. The test specimen is sandwiched between the two load transfer plates and clamped together with the stud. Spacer washers are placed between the test specimen and each load transfer plate to provide a known, controllable area for the determination of clamping forces around the hole of the specimen attributable to bolt torque. The spacer washers also provide a gap for the mounting of reference angles on each side of the test specimen. Under tensile loading, elongation of the hole of the test specimen causes the stud to move away from the reference angles. This displacement is measured by the voltage output of two linear displacement measuring instruments that are attached to the stud and remain in contact with the reference angles throughout the tensile loading. The present invention obviates previous problems in obtaining specimen deformation measurements by monitoring the reference angles to the test specimen and the linear displacement measuring instruments to the stud.

  10. Elongational viscosity of monodisperse and bidisperse polystyrene melts

    DEFF Research Database (Denmark)

    Nielsen, Jens Kromann; Rasmussen, Henrik Koblitz; Hassager, Ole

    2005-01-01

    The startup and steady uniaxial elongational viscosity have been measured for two monodisperse polystyrene melts with molecular weights of 52 kg/mole (PS52K) and 103 kg/mole (PS103K), and for three bidisperse polystyrene melts. The bidisperse melts consist of PS103K or PS52K and a monodisperse...... (closed loop proportional regulator) using the laser in such a way that the stretch rate at the neck is kept constant. The rheometer has been described in more detail in (A. Bach, H.K. Rasmussen and O. Hassager, Journal of Rheology, 47 (2003) 429). PS390K show a decrease in the steady viscosity as a power......-law function of the elongational rate (A. Bach, K. Almdal, H.K. Rasmussen and O. Hassager, Macromolecules 36 (2003) 5174). PS52K and PS103K show that the steady viscosity has a maximum that is respectively 100% and 50% above 3 times the zero-shear-rate viscosity. The bidisperse melts show a significant...

  11. Swimming of a Sea Butterfly with an Elongated Shell

    Science.gov (United States)

    Karakas, Ferhat; Maas, Amy E.; Murphy, David W.

    2017-11-01

    Sea butterflies (pteropods) are small, zooplanktonic marine snails which swim by flapping highly flexible parapodia. Previous studies show that the swimming hydrodynamics of Limacina helicina, a polar pteropod with a spiraled shell, is similar to tiny insect flight aerodynamics and that forward-backward pitching is key for lift generation. However, swimming by diverse pteropod species with different shell shapes has not been examined. We present measurements of the swimming of Cuvierina columnella, a warm water species with an elongated non-spiraled shell collected off the coast of Bermuda. With a body length of 9 mm, wing beat frequency of 4-6 Hz and swimming speed of 35 mm/s, these organisms swim at a Reynolds number of approximately 300, larger than that of L. helicina. High speed 3D kinematics acquired via two orthogonal cameras reveals that the elongated shell correlates with reduced body pitching and that the wings bend approximately 180 degrees in each direction, overlapping at the end of each half-stroke. Time resolved 2D flow measurements collected with a micro-PIV system reveal leading edge vortices present in both power and recovery strokes. Interactions between the overlapping wings and the shell also likely play a role in lift generation.

  12. Initiation and elongation of lateral roots in Lactuca sativa

    Science.gov (United States)

    Zhang, N.; Hasenstein, K. H.

    1999-01-01

    Lactuca sativa cv. Baijianye seedlings do not normally produce lateral roots, but removal of the root tip or application of auxin, especially indole-butyric acid, triggered the formation of lateral roots. Primordia initiated within 9 h and were fully developed after 24 h by activating the pericycle cells opposite the xylem pole. The pericycle cells divided asymmetrically into short and long cells. The short cells divided further to form primordia. The effect of root tip removal and auxin application was reversed by 6-benzylaminopurine at concentrations >10(-8) M. The cytokinin oxidase inhibitor N1-(2chloro4pyridyl)-N2-phenylurea also suppressed auxin-induced lateral rooting. The elongation of primary roots was promoted by L-alpha-(2-aminoethoxyvinyl) glycine and silver ions, but only the latter enhanced elongation of lateral roots. The data indicate that the induction of lateral roots is controlled by basipetally moving cytokinin and acropetally moving auxin. Lateral roots appear to not produce ethylene.

  13. Gibberellin biosynthesis and signal transduction is essential for internode elongation in deepwater rice.

    Science.gov (United States)

    Ayano, Madoka; Kani, Takahiro; Kojima, Mikiko; Sakakibara, Hitoshi; Kitaoka, Takuya; Kuroha, Takeshi; Angeles-Shim, Rosalyn B; Kitano, Hidemi; Nagai, Keisuke; Ashikari, Motoyuki

    2014-10-01

    Under flooded conditions, the leaves and internodes of deepwater rice can elongate above the water surface to capture oxygen and prevent drowning. Our previous studies showed that three major quantitative trait loci (QTL) regulate deepwater-dependent internode elongation in deepwater rice. In this study, we investigated the age-dependent internode elongation in deepwater rice. We also investigated the relationship between deepwater-dependent internode elongation and the phytohormone gibberellin (GA) by physiological and genetic approach using a QTL pyramiding line (NIL-1 + 3 + 12). Deepwater rice did not show internode elongation before the sixth leaf stage under deepwater condition. Additionally, deepwater-dependent internode elongation occurred on the sixth and seventh internodes during the sixth leaf stage. These results indicate that deepwater rice could not start internode elongation until the sixth leaf stage. Ultra-performance liquid chromatography tandem mass-spectrometry (UPLC-MS/MS) method for the phytohormone contents showed a deepwater-dependent GA1 and GA4 accumulation in deepwater rice. Additionally, a GA inhibitor abolished deepwater-dependent internode elongation in deepwater rice. On the contrary, GA feeding mimicked internode elongation under ordinary growth conditions. However, mutations in GA biosynthesis and signal transduction genes blocked deepwater-dependent internode elongation. These data suggested that GA biosynthesis and signal transduction are essential for deepwater-dependent internode elongation in deepwater rice. © 2014 The Authors. Plant, Cell & Environment published by John Wiley & Sons Ltd.

  14. Measurement and analysis of pressure tube elongation in the Douglas Point reactor

    International Nuclear Information System (INIS)

    Causey, A.R.; MacEwan, S.R.; Jamieson, H.C.; Mitchell, A.B.

    1980-02-01

    Elongations of zirconium alloy pressure tubes in CANDU reactors, which occur as a result of neutron-irradiation-induced creep and growth, have been measured over the past 6 years, and the consequences of thses elongations have recently been analysed. Elongation rates, previously deduced from extensive measurements of elongations of cold-worked Zircaloy-2 pressure tubes in the Pickering reactors, have been modified to apply to the pressure tubes in the Douglas Point (DP) reactor by taking into account measured diffences in texture and dislocation density. Using these elongation rates, and structural data unique to the DP reactor, the analysis predicts elongation behaviour which is in good agreement with pressure tube elongations measured during the ten years of reactor operation. (Auth)

  15. Super continuum generation at 800 nm in highly nonlinear photonic crystal fibers with normal dispersion

    DEFF Research Database (Denmark)

    Hansen, Kim Per; Larsen, Jacob Juul; Jensen, Jacob Riis

    2001-01-01

    More than 90 nm broad self-phase modulation (SPM) induced pulses have been created from both 25 and 50 fs pulses in just 12.5 cm of fiber. The broadening is more than 2.5 times that observed in standard SMF. SPM broadening in PCFs has several advantages over more complex super continuum generatio...

  16. The calculation of deep levels in semiconductors by using a recursion method for super-cells

    International Nuclear Information System (INIS)

    Wong Yongliang.

    1987-01-01

    The paper presents the theory of deep levels in semiconductors, the super-cell approach to the theory of deep level impurities, the calculation of band structure by using the tight-binding method and the recursion method used to study the defects in the presence of lattice relaxation and extended defect complexes. 47 refs

  17. Super-quasi-conformal transformation and Schiffer variation on super-Riemann surface

    International Nuclear Information System (INIS)

    Takahasi, Wataru

    1990-01-01

    A set of equations which characterizes the super-Teichmueller deformations is proposed. It is a supersymmetric extension of the Beltrami equation. Relations between the set of equations and the Schiffer variations with the KN bases are discussed. This application of the KN bases shows the powerfulness of the KN theory in the study of super-Riemann surfaces. (author)

  18. Deterministic phase measurements exhibiting super-sensitivity and super-resolution

    DEFF Research Database (Denmark)

    Schäfermeier, Clemens; Ježek, Miroslav; Madsen, Lars S.

    2018-01-01

    Phase super-sensitivity is obtained when the sensitivity in a phase measurement goes beyond the quantum shot noise limit, whereas super-resolution is obtained when the interference fringes in an interferometer are narrower than half the input wavelength. Here we show experimentally that these two...

  19. SuperB Progress Report for Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Biagini, M.E.; Boni, R.; Boscolo, M.; Buonomo, B.; Demma, T.; Drago, A.; Esposito, M.; Guiducci, S.; Mazzitelli, G.; Pellegrino, L.; Preger, M.A.; Raimondi, P.; Ricci, R.; Rotundo, U.; Sanelli, C.; Serio, M.; Stella, A.; Tomassini, S.; Zobov, M.; /Frascati; Bertsche, K.; Brachman, A.; /SLAC /Novosibirsk, IYF /INFN, Pisa /Pisa U. /Orsay, LAL /Annecy, LAPP /LPSC, Grenoble /IRFU, SPP, Saclay /DESY /Cockroft Inst. Accel. Sci. Tech. /U. Liverpool /CERN

    2012-02-14

    This report details the progress made in by the SuperB Project in the area of the Collider since the publication of the SuperB Conceptual Design Report in 2007 and the Proceedings of SuperB Workshop VI in Valencia in 2008. With this document we propose a new electron positron colliding beam accelerator to be built in Italy to study flavor physics in the B-meson system at an energy of 10 GeV in the center-of-mass. This facility is called a high luminosity B-factory with a project name 'SuperB'. This project builds on a long history of successful e+e- colliders built around the world, as illustrated in Figure 1.1. The key advances in the design of this accelerator come from recent successes at the DAFNE collider at INFN in Frascati, Italy, at PEP-II at SLAC in California, USA, and at KEKB at KEK in Tsukuba Japan, and from new concepts in beam manipulation at the interaction region (IP) called 'crab waist'. This new collider comprises of two colliding beam rings, one at 4.2 GeV and one at 6.7 GeV, a common interaction region, a new injection system at full beam energies, and one of the two beams longitudinally polarized at the IP. Most of the new accelerator techniques needed for this collider have been achieved at other recently completed accelerators including the new PETRA-3 light source at DESY in Hamburg (Germany) and the upgraded DAFNE collider at the INFN laboratory at Frascati (Italy), or during design studies of CLIC or the International Linear Collider (ILC). The project is to be designed and constructed by a worldwide collaboration of accelerator and engineering staff along with ties to industry. To save significant construction costs, many components from the PEP-II collider at SLAC will be recycled and used in this new accelerator. The interaction region will be designed in collaboration with the particle physics detector to guarantee successful mutual use. The accelerator collaboration will consist of several groups at present

  20. ATLAS FTK a – very complex – custom super computer

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00008600; The ATLAS collaboration

    2016-01-01

    In the ever increasing pile-up LHC environment advanced techniques of analyzing the data are implemented in order to increase the rate of relevant physics processes with respect to background processes. The Fast TracKer (FTK) is a track finding implementation at hardware level that is designed to deliver full-scan tracks with PT above 1GeV to the ATLAS trigger system for every L1 accept (at a maximum rate of 100kHz). In order to achieve this performance a highly parallel system was designed and now it is under installation in ATLAS. In the beginning of 2016 it will provide tracks for the trigger system in a region covering the central part of the ATLAS detector, and during the year it's coverage will be extended to the full detector coverage. The system relies on matching hits coming from the silicon tracking detectors against 1 billion patterns stored in specially designed ASICS chips (Associative memory - AM06). In a first stage coarse resolution hits are matched against the patterns and the accepted hits u...

  1. ATLAS FTK a - very complex - custom super computer

    International Nuclear Information System (INIS)

    Kimura, N

    2016-01-01

    In the LHC environment for high interaction pile-up, advanced techniques of analysing the data in real time are required in order to maximize the rate of physics processes of interest with respect to background processes. The Fast TracKer (FTK) is a track finding implementation at the hardware level that is designed to deliver full-scan tracks with p T above 1 GeV to the ATLAS trigger system for events passing the Level-1 accept (at a maximum rate of 100 kHz). In order to achieve this performance, a highly parallel system was designed and currently it is being commissioned within in ATLAS. Starting in 2016 it will provide tracks for the trigger system in a region covering the central part of the ATLAS detector, and will be extended to the full detector coverage. The system relies on matching hits coming from the silicon tracking detectors against one billion patterns stored in custom ASIC chips (Associative memory chip - AM06). In a first stage, coarse resolution hits are matched against the patterns and the accepted hits undergo track fitting implemented in FPGAs. Tracks with p T > 1GeV are delivered to the High Level Trigger within about 100 ps. Resolution of the tracks coming from FTK is close to the offline tracking and it will allow for reliable detection of primary and secondary vertexes at trigger level and improved trigger performance for b-jets and tau leptons. This contribution will give an overview of the FTK system and present the status of commissioning of the system. Additionally, the expected FTK performance will be briefly described. (paper)

  2. Loss of elongation factor P disrupts bacterial outer membrane integrity

    DEFF Research Database (Denmark)

    Zou, S Betty; Hersch, Steven J; Roy, Hervé

    2012-01-01

    background ameliorates the detergent, antibiotic, and osmosensitivity phenotypes and restores wild-type permeability to NPN. Our data support a role for EF-P in the translational regulation of a limited number of proteins that, when perturbed, renders the cell susceptible to stress by the adventitious......Elongation factor P (EF-P) is posttranslationally modified at a conserved lysyl residue by the coordinated action of two enzymes, PoxA and YjeK. We have previously established the importance of this modification in Salmonella stress resistance. Here we report that, like poxA and yjeK mutants......, Salmonella strains lacking EF-P display increased susceptibility to hypoosmotic conditions, antibiotics, and detergents and enhanced resistance to the compound S-nitrosoglutathione. The susceptibility phenotypes are largely explained by the enhanced membrane permeability of the efp mutant, which exhibits...

  3. Sigmoid Colon Elongation Evaluation by Volume Rendering Technique

    Directory of Open Access Journals (Sweden)

    Atilla SENAYLI

    2011-06-01

    Full Text Available Sigmoid colons have various measurements, shapes, and configurations for individuals. In this subject there are rare clinical trials to answer the question of sigmoidal colon maldevelopment predicting a risk for volvulus. Therefore, sigmoid colon measurement may be beneficial to decide for volvulus. In a study, sigmoid colon diameters were evaluated during abdominal surgeries and it was found that median length was 47 cm and median vertical mesocolon length was 13 cm. We report a 14-year-old female patient who has a sigmoidal colon measured as nearly 54 cm. We used tomographic equipments for this evaluation. We know that MRI technique was used for this purpose but, there has not been data for MRI predicting the sigmoidal volvulus. We hope that our findings by this evaluation can contribute to insufficient literature of sigmoidal elongation. [J Contemp Med 2011; 1(2.000: 71-73

  4. Elongational rheology and cohesive fracture of photo-oxidated LDPE

    Energy Technology Data Exchange (ETDEWEB)

    Rolón-Garrido, Víctor H., E-mail: victor.h.rolongarrido@tu-berlin.de; Wagner, Manfred H. [Chair of Polymer Engineering/Polymer Physics, Berlin Institute of Technology (TU Berlin), Fasanenstrasse 90, D-10623 Berlin (Germany)

    2014-01-15

    It was found recently that low-density polyethylene (LDPE) samples with different degrees of photo-oxidation represent an interesting system to study the transition from ductile to cohesive fracture and the aspects of the cohesive rupture in elongational flow. Sheets of LDPE were subjected to photo-oxidation in the presence of air using a xenon lamp to irradiate the samples for times between 1 day and 6 weeks. Characterisation methods included Fourier transform infrared spectroscopy, solvent extraction method, and rheology in shear and uniaxial extensional flows. Linear viscoelasticity was increasingly affected by increasing photo-oxidation due to crosslinking of LDPE, as corroborated by the carbonyl index, acid and aldehydes groups, and gel fraction. The molecular stress function model was used to quantify the experimental data, and the nonlinear model parameter β was found to be correlated with the gel content. The uniaxial data showed that the transition from ductile to cohesive fracture was shifted to lower elongational rates, the higher the gel content was. From 2 weeks photo-oxidation onwards, cohesive rupture occurred at every strain rate investigated. The true strain and true stress at cohesive fracture as well as the energy density applied to the sample up to fracture were analyzed. At low gel content, rupture was mainly determined by the melt fraction while at high gel content, rupture occurred predominantly in the gel structure. The strain at break was found to be independent of strain rate, contrary to the stress at break and the energy density. Thus, the true strain and not the stress at break or the energy density was found to be the relevant physical quantity to describe cohesive fracture behavior of photo-oxidated LDPE. The equilibrium modulus of the gel structures was correlated with the true strain at rupture. The stiffer the gel structure, the lower was the deformation tolerated before the sample breaks.

  5. Dendrosomatic Sonic Hedgehog Signaling in Hippocampal Neurons Regulates Axon Elongation

    Science.gov (United States)

    Petralia, Ronald S.; Ott, Carolyn; Wang, Ya-Xian; Lippincott-Schwartz, Jennifer; Mattson, Mark P.

    2015-01-01

    The presence of Sonic Hedgehog (Shh) and its signaling components in the neurons of the hippocampus raises a question about what role the Shh signaling pathway may play in these neurons. We show here that activation of the Shh signaling pathway stimulates axon elongation in rat hippocampal neurons. This Shh-induced effect depends on the pathway transducer Smoothened (Smo) and the transcription factor Gli1. The axon itself does not respond directly to Shh; instead, the Shh signal transduction originates from the somatodendritic region of the neurons and occurs in neurons with and without detectable primary cilia. Upon Shh stimulation, Smo localization to dendrites increases significantly. Shh pathway activation results in increased levels of profilin1 (Pfn1), an actin-binding protein. Mutations in Pfn1's actin-binding sites or reduction of Pfn1 eliminate the Shh-induced axon elongation. These findings indicate that Shh can regulate axon growth, which may be critical for development of hippocampal neurons. SIGNIFICANCE STATEMENT Although numerous signaling mechanisms have been identified that act directly on axons to regulate their outgrowth, it is not known whether signals transduced in dendrites may also affect axon outgrowth. We describe here a transcellular signaling pathway in embryonic hippocampal neurons in which activation of Sonic Hedgehog (Shh) receptors in dendrites stimulates axon growth. The pathway involves the dendritic-membrane-associated Shh signal transducer Smoothened (Smo) and the transcription factor Gli, which induces the expression of the gene encoding the actin-binding protein profilin 1. Our findings suggest scenarios in which stimulation of Shh in dendrites results in accelerated outgrowth of the axon, which therefore reaches its presumptive postsynaptic target cell more quickly. By this mechanism, Shh may play critical roles in the development of hippocampal neuronal circuits. PMID:26658865

  6. The Effects of Microgravity on Seated Height (Spinal Elongation)

    Science.gov (United States)

    Young, K. S.; Rajulu, S.

    2011-01-01

    ABSTRACT Many physiological factors, such as spinal elongation, fluid shifts, bone atrophy, and muscle loss, occur during an exposure to a microgravity environment. Spinal elongation is just one of the factors that can also affect the safety and performance of a crewmember while in space. Spinal elongation occurs due to the lack of gravity/compression on the spinal column. This allows for the straightening of the natural spinal curve. There is a possible fluid shift in the inter-vertebral disks that may also result in changes in height. This study aims at collecting the overall change in seated height for crewmembers exposed to a microgravity environment. During previous Programs, Apollo-Soyuz Test Project (ASTP) and Skylab, spinal elongation data was collected from a small number of subjects in a standing posture but were limited in scope. Data from these studies indicated a quick increase in stature during the first few days of weightlessness, after which stature growth reached a plateau resulting in up to a 3% increase of the original measurement [1-5]. However, this data was collected only for crewmembers in standing posture and not in a seated posture. Seated height may have a different effect than standing height due to a change in posture as well as due to a compounded effect of wearing restraints and a potential compression of the gluteal area. Seated height was deemed as a critical measurement in the design of the Constellation Program s (CxP) Crew Exploration Vehicle (CEV), called Orion which is now the point-of-departure vehicle for the Multi-Purpose Crew Vehicle (MPCV) Program; therefore a better understanding of the effects of microgravity on seated height is necessary. Potential changes in seated height that may not have impacted crew accommodation in previous Programs will have significant effects on crew accommodation due to the layout of seats in the Orion.. The current and existing configuration is such that the four crewmembers are stacked two by

  7. SuperAGILE Services at ASDC

    International Nuclear Information System (INIS)

    Preger, B.; Verrecchia, F.; Pittori, C.; Antonelli, L. A.; Giommi, P.; Lazzarotto, F.; Evangelista, Y.

    2008-01-01

    The Italian Space Agency Science Data Center (ASDC) is a facility with several responsibilities including support to all the ASI scientific missions as for management and archival of the data, acting as the interface between ASI and the scientific community and providing on-line access to the data hosted. In this poster we describe the services that ASDC provides for SuperAGILE, in particular the ASDC public web pages devoted to the dissemination of SuperAGILE scientific results. SuperAGILE is the X-Ray imager onboard the AGILE mission, and provides the scientific community with orbit-by-orbit information on the observed sources. Crucial source information including position and flux in chosen energy bands will be reported in the SuperAGILE public web page at ASDC. Given their particular interest, another web page will be dedicated entirely to GRBs and other transients, where new event alerts will be notified and where users will find all the available informations on the GRBs detected by SuperAGILE

  8. Learning from errors in super-resolution.

    Science.gov (United States)

    Tang, Yi; Yuan, Yuan

    2014-11-01

    A novel framework of learning-based super-resolution is proposed by employing the process of learning from the estimation errors. The estimation errors generated by different learning-based super-resolution algorithms are statistically shown to be sparse and uncertain. The sparsity of the estimation errors means most of estimation errors are small enough. The uncertainty of the estimation errors means the location of the pixel with larger estimation error is random. Noticing the prior information about the estimation errors, a nonlinear boosting process of learning from these estimation errors is introduced into the general framework of the learning-based super-resolution. Within the novel framework of super-resolution, a low-rank decomposition technique is used to share the information of different super-resolution estimations and to remove the sparse estimation errors from different learning algorithms or training samples. The experimental results show the effectiveness and the efficiency of the proposed framework in enhancing the performance of different learning-based algorithms.

  9. Magnetic Resonance Super-resolution Imaging Measurement with Dictionary-optimized Sparse Learning

    Directory of Open Access Journals (Sweden)

    Li Jun-Bao

    2017-06-01

    Full Text Available Magnetic Resonance Super-resolution Imaging Measurement (MRIM is an effective way of measuring materials. MRIM has wide applications in physics, chemistry, biology, geology, medical and material science, especially in medical diagnosis. It is feasible to improve the resolution of MR imaging through increasing radiation intensity, but the high radiation intensity and the longtime of magnetic field harm the human body. Thus, in the practical applications the resolution of hardware imaging reaches the limitation of resolution. Software-based super-resolution technology is effective to improve the resolution of image. This work proposes a framework of dictionary-optimized sparse learning based MR super-resolution method. The framework is to solve the problem of sample selection for dictionary learning of sparse reconstruction. The textural complexity-based image quality representation is proposed to choose the optimal samples for dictionary learning. Comprehensive experiments show that the dictionary-optimized sparse learning improves the performance of sparse representation.

  10. Extraordinary Light-Trapping Enhancement in Silicon Solar Cell Patterned with Graded Photonic Super-Crystals

    Directory of Open Access Journals (Sweden)

    Safaa Hassan

    2017-12-01

    Full Text Available Light-trapping enhancement in newly discovered graded photonic super-crystals (GPSCs with dual periodicity and dual basis is herein explored for the first time. Broadband, wide-incident-angle, and polarization-independent light-trapping enhancement was achieved in silicon solar cells patterned with these GPSCs. These super-crystals were designed by multi-beam interference, rendering them flexible and efficient. The optical response of the patterned silicon solar cell retained Bloch-mode resonance; however, light absorption was greatly enhanced in broadband wavelengths due to the graded, complex unit super-cell nanostructures, leading to the overlap of Bloch-mode resonances. The broadband, wide-angle light coupling and trapping enhancement mechanism are understood to be due to the spatial variance of the index of refraction, and this spatial variance is due to the varying filling fraction, the dual basis, and the varying lattice constants in different directions.

  11. Fabricating Super-hydrophobic Polydimethylsiloxane Surfaces by a Simple Filler-Dissolved Process

    Science.gov (United States)

    Lin, Yung-Tsan; Chou, Jung-Hua

    2010-12-01

    The self-cleaning effect of super-hydrophobic surfaces has attracted the attention of researchers. Typical ways of manufacturing super-hydrophobic surfaces include the use of either dedicated equipment or a complex chemical process. In this study, a simple innovative filler-dissolved method is developed using mainly powder salt and rinsing to form hydrophobic surfaces. This method can produce large super-hydrophobic surfaces with porous and micro rib surface structures. It can also be applied to curved surfaces, including flexible membranes. The contact angle of the manufactured artificial hydrophobic surface is about 160°. Furthermore, water droplets roll off the surface readily at a sliding angle of less than 5°, resembling the nonwetting lotus like effect.

  12. Advanced heat pumps and their economic aspects. The case for super heat pump

    International Nuclear Information System (INIS)

    Yabe, Akira; Akiya, Takaji

    1996-01-01

    The results of the economic evaluation of the Super Heat Pump Energy Accumulation System project in Japan are reviewed. It is reported that although the initial costs of super heat pumps are higher than those of conventional systems, the calculated operating costs of a unit thermal energy produced by a super heat pump is reduced considerably. All the various system concepts with thermal/chemical storage were evaluated economically with the exception of the high temperature thermal storage systems using salt ammonia complexes and solvation. These latter systems were not further developed as pilot plants. It is advocated to accelerate the introduction of super heat pumps by facilitating their market introduction. Actual clathrate chemical storage systems have shown that the annual costs are comparable to those of an ice storage system. Clathrate systems will find their way in the market. It is concluded that most of the super heat pump systems and clathrate storage systems will be economic in the future. A big challenge however still exists in further improving the cost effectiveness of heat storage in tanks by reducing their size dramatically (to 1/10th)

  13. Pinching parameters for open (super) strings

    Science.gov (United States)

    Playle, Sam; Sciuto, Stefano

    2018-02-01

    We present an approach to the parametrization of (super) Schottky space obtained by sewing together three-punctured discs with strips. Different cubic ribbon graphs classify distinct sets of pinching parameters; we show how they are mapped onto each other. The parametrization is particularly well-suited to describing the region within (super) moduli space where open bosonic or Neveu-Schwarz string propagators become very long and thin, which dominates the IR behaviour of string theories. We show how worldsheet objects such as the Green's function converge to graph theoretic objects such as the Symanzik polynomials in the α ' → 0 limit, allowing us to see how string theory reproduces the sum over Feynman graphs. The (super) string measure takes on a simple and elegant form when expressed in terms of these parameters.

  14. Stacked generalization: an introduction to super learning.

    Science.gov (United States)

    Naimi, Ashley I; Balzer, Laura B

    2018-04-10

    Stacked generalization is an ensemble method that allows researchers to combine several different prediction algorithms into one. Since its introduction in the early 1990s, the method has evolved several times into a host of methods among which is the "Super Learner". Super Learner uses V-fold cross-validation to build the optimal weighted combination of predictions from a library of candidate algorithms. Optimality is defined by a user-specified objective function, such as minimizing mean squared error or maximizing the area under the receiver operating characteristic curve. Although relatively simple in nature, use of Super Learner by epidemiologists has been hampered by limitations in understanding conceptual and technical details. We work step-by-step through two examples to illustrate concepts and address common concerns.

  15. Transcriptome Sequencing and Analysis for Culm Elongation of the World's Largest Bamboo (Dendrocalamus sinicus.

    Directory of Open Access Journals (Sweden)

    Kai Cui

    Full Text Available Dendrocalamus sinicus is the world's largest bamboo species with strong woody culms, and known for its fast-growing culms. As an economic bamboo species, it was popularized for multi-functional applications including furniture, construction, and industrial paper pulp. To comprehensively elucidate the molecular processes involved in its culm elongation, Illumina paired-end sequencing was conducted. About 65.08 million high-quality reads were produced, and assembled into 81,744 unigenes with an average length of 723 bp. A total of 64,338 (79% unigenes were annotated for their functions, of which, 56,587 were annotated in the NCBI non-redundant protein database and 35,262 were annotated in the Swiss-Prot database. Also, 42,508 and 21,009 annotated unigenes were allocated to gene ontology (GO categories and clusters of orthologous groups (COG, respectively. By searching against the Kyoto Encyclopedia of Genes and Genomes Pathway database (KEGG, 33,920 unigenes were assigned to 128 KEGG pathways. Meanwhile, 8,553 simple sequence repeats (SSRs and 81,534 single-nucleotide polymorphism (SNPs were identified, respectively. Additionally, 388 transcripts encoding lignin biosynthesis were detected, among which, 27 transcripts encoding Shikimate O-hydroxycinnamoyltransferase (HCT specifically expressed in D. sinicus when compared to other bamboo species and rice. The phylogenetic relationship between D. sinicus and other plants was analyzed, suggesting functional diversity of HCT unigenes in D. sinicus. We conjectured that HCT might lead to the high lignin content and giant culm. Given that the leaves are not yet formed and culm is covered with sheaths during culm elongation, the existence of photosynthesis of bamboo culm is usually neglected. Surprisedly, 109 transcripts encoding photosynthesis were identified, including photosystem I and II, cytochrome b6/f complex, photosynthetic electron transport and F-type ATPase, and 24 transcripts were characterized

  16. Transcriptome Sequencing and Analysis for Culm Elongation of the World's Largest Bamboo (Dendrocalamus sinicus).

    Science.gov (United States)

    Cui, Kai; Wang, Haiying; Liao, Shengxi; Tang, Qi; Li, Li; Cui, Yongzhong; He, Yuan

    2016-01-01

    Dendrocalamus sinicus is the world's largest bamboo species with strong woody culms, and known for its fast-growing culms. As an economic bamboo species, it was popularized for multi-functional applications including furniture, construction, and industrial paper pulp. To comprehensively elucidate the molecular processes involved in its culm elongation, Illumina paired-end sequencing was conducted. About 65.08 million high-quality reads were produced, and assembled into 81,744 unigenes with an average length of 723 bp. A total of 64,338 (79%) unigenes were annotated for their functions, of which, 56,587 were annotated in the NCBI non-redundant protein database and 35,262 were annotated in the Swiss-Prot database. Also, 42,508 and 21,009 annotated unigenes were allocated to gene ontology (GO) categories and clusters of orthologous groups (COG), respectively. By searching against the Kyoto Encyclopedia of Genes and Genomes Pathway database (KEGG), 33,920 unigenes were assigned to 128 KEGG pathways. Meanwhile, 8,553 simple sequence repeats (SSRs) and 81,534 single-nucleotide polymorphism (SNPs) were identified, respectively. Additionally, 388 transcripts encoding lignin biosynthesis were detected, among which, 27 transcripts encoding Shikimate O-hydroxycinnamoyltransferase (HCT) specifically expressed in D. sinicus when compared to other bamboo species and rice. The phylogenetic relationship between D. sinicus and other plants was analyzed, suggesting functional diversity of HCT unigenes in D. sinicus. We conjectured that HCT might lead to the high lignin content and giant culm. Given that the leaves are not yet formed and culm is covered with sheaths during culm elongation, the existence of photosynthesis of bamboo culm is usually neglected. Surprisedly, 109 transcripts encoding photosynthesis were identified, including photosystem I and II, cytochrome b6/f complex, photosynthetic electron transport and F-type ATPase, and 24 transcripts were characterized as antenna

  17. Light quality and elongation growth. 1: Effect of duration and time of far red irradiation on stem elongation of Argyranthemum frutescens cv. Silver Leaf

    International Nuclear Information System (INIS)

    Jatzkowski, M.; Zimmer, K.

    1994-01-01

    The phenomenon of stem elongation by far red irradiation was shown with Argyranthemum frutescens 'Silver Leaf'. Stem elongation was promoted by incandescent lighting (mainly far red) during the day and night period. More intense reactions were observed with the isolated application during the nighttime. Reaction was strongly modified by the point of time the application took place. No effect could be shown by lighting with incandescent lamps for two hours during the daytime given within the first six hours of the main light period. During the nighttime two hours of lighting (incandescent lamps) promoted stem elongation atany point of time, especially in the middle of the dark period

  18. Super-Laplacians and their symmetries

    International Nuclear Information System (INIS)

    Howe, P.S.; Lindström, University

    2017-01-01

    A super-Laplacian is a set of differential operators in superspace whose highest-dimensional component is given by the spacetime Laplacian. Symmetries of super-Laplacians are given by linear differential operators of arbitrary finite degree and are determined by superconformal Killing tensors. We investigate these in flat superspaces. The differential operators determining the symmetries give rise to algebras which can be identified in many cases with the tensor algebras of the relevant superconformal Lie algebras modulo certain ideals. They have applications to Higher Spin theories.

  19. Super-Laplacians and their symmetries

    Energy Technology Data Exchange (ETDEWEB)

    Howe, P.S. [Department of Mathematics, King’s College London,The Strand, London, WC2R 2LS (United Kingdom); Lindström, University [Department of Physics and Astronomy, Theoretical Physics, Uppsala University,Uppsala, SE-751 20 (Sweden); Theoretical Physics, Imperial College London,Prince Consort Road, London, SW7 2AZ (United Kingdom)

    2017-05-22

    A super-Laplacian is a set of differential operators in superspace whose highest-dimensional component is given by the spacetime Laplacian. Symmetries of super-Laplacians are given by linear differential operators of arbitrary finite degree and are determined by superconformal Killing tensors. We investigate these in flat superspaces. The differential operators determining the symmetries give rise to algebras which can be identified in many cases with the tensor algebras of the relevant superconformal Lie algebras modulo certain ideals. They have applications to Higher Spin theories.

  20. Acoustic Design of Super-light Structures

    DEFF Research Database (Denmark)

    Christensen, Jacob Ellehauge; Hertz, Kristian Dahl; Brunskog, Jonas

    in a controlled laboratory environment have been conducted with the element in order to evaluate its performance in airborne and impact sound insulation. These results have been employed in simulations of the flanking transmission to estimate the in-situ performance of the super-light slab element. The flanking...... aggregate (leca) along with a newly developed technology called pearl-chain reinforcement, which is a system for post-tensioning. Here, it is shown how to combine these technologies within a precast super-light slab element, while honoring the requirements of a holistic design. Acoustic experiments...

  1. Super-preshowers (DPG-Fruehjahrstagung 2016)

    Energy Technology Data Exchange (ETDEWEB)

    Kaeaepae, Alex [Bergische Universitaet Wuppertal, Gaussstr. 20, 42119 Wuppertal (Germany); Collaboration: Pierre-Auger-Collaboration

    2016-07-01

    Based on the current data from the Pierre Auger Observatory, no evidence of cosmic ray photon primaries has been found. However, photon primaries could induce so-called ''super-preshowers'', which have not been considered sofar, but are a promising candidate for explaining the ''composition puzzle'' at ultra-high energies. In this presentation, possible super-preshower processes are examined, and their effects on important Auger parameters, such as the energy deposit and muon production, are studied via simulations.

  2. KML Super Overlay to WMS Translator

    Science.gov (United States)

    Plesea, Lucian

    2007-01-01

    This translator is a server-based application that automatically generates KML super overlay configuration files required by Google Earth for map data access via the Open Geospatial Consortium WMS (Web Map Service) standard. The translator uses a set of URL parameters that mirror the WMS parameters as much as possible, and it also can generate a super overlay subdivision of any given area that is only loaded when needed, enabling very large areas of coverage at very high resolutions. It can make almost any dataset available as a WMS service visible and usable in any KML application, without the need to reformat the data.

  3. Super ACO FEL oscillation at 300 nm

    CERN Document Server

    Nutarelli, D; Renault, E; Nahon, L; Couprie, Marie Emmanuelle

    2000-01-01

    Some recent improvements, involving both the optical cavity mirrors and the positron beam dynamics in the storage ring, have allowed us to achieve a laser oscillation at 300 nm on the Super ACO Storage Ring FEL. The Super ACO storage ring is operated at 800 MeV which is the nominal energy for the usual synchrotron radiation users, and the highest energy for a storage ring FEL. The lasing at 300 nm could be kept during 2 h per injection, with a stored current ranging between 30 and 60 mA. The FEL characteristics are presented here. The longitudinal stability and the FEL optics behaviour are also discussed.

  4. Covariant super reggeon calculus for superstrings

    International Nuclear Information System (INIS)

    Petersen, J.L.; Sidenius, J.R.; Tollsten, A.K.

    1988-07-01

    A previously developed formalism for the bosonic string is extended to the Neveu-Schwarz-Ramond string using 2-d superspace techniques throughout. 3-string vertices for NS- and R-strings are constructed, sewing rules developed, and the technique of quasi-superconformal modes is set up for constructing the measure on super moduli space. Symmetries, such as superconformal invariance and BRST-invariance, are guaranteed ab initio. Picture changing and bosonization are avoided. Examples are given. The formalism should allow a superstring loop calculus based on supermoduli. Results concerning the ensuing super-Schottky description are given. (orig.)

  5. Temporal super resolution using variational methods

    DEFF Research Database (Denmark)

    Keller, Sune Høgild; Lauze, Francois Bernard; Nielsen, Mads

    2010-01-01

    Temporal super resolution (TSR) is the ability to convert video from one frame rate to another and is as such a key functionality in modern video processing systems. A higher frame rate than what is recorded is desired for high frame rate displays, for super slow-motion, and for video/film format...... observed when watching video on large and bright displays where the motion of high contrast edges often seem jerky and unnatural. A novel motion compensated (MC) TSR algorithm using variational methods for both optical flow calculation and the actual new frame interpolation is presented. The flow...

  6. Endogenous abscisic acid as a key switch for natural variation in flooding-induced shoot elongation.

    Science.gov (United States)

    Chen, Xin; Pierik, Ronald; Peeters, Anton J M; Poorter, Hendrik; Visser, Eric J W; Huber, Heidrun; de Kroon, Hans; Voesenek, Laurentius A C J

    2010-10-01

    Elongation of leaves and stem is a key trait for survival of terrestrial plants during shallow but prolonged floods that completely submerge the shoot. However, natural floods at different locations vary strongly in duration and depth, and, therefore, populations from these locations are subjected to different selection pressure, leading to intraspecific variation. Here, we identified the signal transduction component that causes response variation in shoot elongation among two accessions of the wetland plant Rumex palustris. These accessions differed 2-fold in petiole elongation rates upon submergence, with fast elongation found in a population from a river floodplain and slow elongation in plants from a lake bank. Fast petiole elongation under water consumes carbohydrates and depends on the (inter)action of the plant hormones ethylene, abscisic acid, and gibberellic acid. We found that carbohydrate levels and dynamics in shoots did not differ between the fast and slow elongating plants, but that the level of ethylene-regulated abscisic acid in petioles, and hence gibberellic acid responsiveness of these petioles explained the difference in shoot elongation upon submergence. Since this is the exact signal transduction level that also explains the variation in flooding-induced shoot elongation among plant species (namely, R. palustris and Rumex acetosa), we suggest that natural selection results in similar modification of regulatory pathways within and between species.

  7. On the monodromy group for the super Schwarzian differential equation

    International Nuclear Information System (INIS)

    Uehara, Shozo; Yasui, Yukinori.

    1991-03-01

    We calculate the first variation of the monodromy group associated with a super Schwarzian differential equation. The relation between the monodromy period and the Fenchel-Nielsen deformation of a super Riemann surface is presented. (author)

  8. Mutational analysis of Escherichia coli elongation factor Tu in search of a role for the N-terminal region

    DEFF Research Database (Denmark)

    Mansilla, Francisco; Knudsen, Charlotte Rohde; Laurberg, M

    1998-01-01

    We have mutated lysine 2 and arginine 7 in elongation factor Tu from Escherichia coli separately either to alanine or glutamic acid. The aim of the work was to reveal the possible interactions between the conserved N-terminal part of the molecule, which is rich in basic residues and aminoacyl...... this activity. Furthermore, arginine 7 seems to play a role in regulating the binding of GTP. The three-dimensional structure of the ternary complex, EF-Tu:GTP:Phe-tRNAPhe, involving Thermus aquaticus EF-Tu and yeast Phe-tRNA(Phe), shows that Arg7 is in a position which permits salt bridge formation with Asp284...

  9. Super-Virtual Refraction Interferometric Redatuming: Enhancing the Refracted Energy

    KAUST Repository

    Aldawood, Ali

    2012-02-26

    onshore seismic data processing. Refraction tomography is becoming a common way to estimate an accurate near surface velocity model. One of the problems with refraction tomography is the low signal to noise ration in far offset data. To improve, we propose using super-virtual refraction interferometry to enhance the weak energy at far offsets. We use Interferometric Green\\'s functions to redatum sources by cross-correlating two traces recorded at receiver stations, A and B, from a source at location W. The result is a redatumed trace with a virtual source at A and a receiver at B, which can also be obtained by correlating two traces recorded at A and B from different shots. Stacking them would enhance the signal-to-noise ratio of this "virtual" trace. We next augment redatuming with convolution and stacking. The trace recorded at B from a virtual source at A is convolved with the original trace recorded at A from a source at W. The result is a "super-virtual" trace at B in the far-offset from a source at W. Stacking N traces gives a vN-improvement. We applied our method to noisy synthetic and field data recorded over a complex near-surface and we could pick more traces at far offsets. It was possible to accommodate more picks resulting in a better subsurface coverage

  10. Super Picard-Fuchs equation and monodromies for supermanifolds

    International Nuclear Information System (INIS)

    Kaura, Payal; Misra, Aalok; Shukla, Pramod

    2007-01-01

    Following, Aganagic and Vafa (e-print hep-th/0403192) and Hori and Vafa (e-print hep-th/0002222), we discuss the Picard-Fuchs equation for the super Landau-Ginsburg mirror to the super Calabi-Yau in WCP (3vertical bar2) [1,1,1,3 vertical bar 1,5] (using techniques of Greene and Lazaroiu [Nucl. Phys. B 604, 181 (2001), e-print hep-th/0001025] and Misra [Fortschr. Phys. 52, 831 (2004), e-print hep-th/0311186]), Meijer basis of solutions, and monodromies (at 0,1 and ∞) in the large and small complex structure limits, as well as obtain the mirror hypersurface, which in the large Kaehler limit turns out to be either a bidegree-(6,6) hypersurface in WCP (3|1) [1,1,1,2]xWCP (1vertical bar1) [1,1 vertical bar 6] or a (Z 2 singular) bidegree-(6,12) hypersurface in WCP (3vertical bar1) [1,1,2,6 vertical bar 6]xWCP (1vertical bar1) [1,1 vertical bar 6

  11. Super-Virtual Refraction Interferometric Redatuming: Enhancing the Refracted Energy

    KAUST Repository

    Aldawood, Ali; Alshuhail, Abdulrahman Abdullatif Abdulrahman; Hanafy, Sherif

    2012-01-01

    onshore seismic data processing. Refraction tomography is becoming a common way to estimate an accurate near surface velocity model. One of the problems with refraction tomography is the low signal to noise ration in far offset data. To improve, we propose using super-virtual refraction interferometry to enhance the weak energy at far offsets. We use Interferometric Green's functions to redatum sources by cross-correlating two traces recorded at receiver stations, A and B, from a source at location W. The result is a redatumed trace with a virtual source at A and a receiver at B, which can also be obtained by correlating two traces recorded at A and B from different shots. Stacking them would enhance the signal-to-noise ratio of this "virtual" trace. We next augment redatuming with convolution and stacking. The trace recorded at B from a virtual source at A is convolved with the original trace recorded at A from a source at W. The result is a "super-virtual" trace at B in the far-offset from a source at W. Stacking N traces gives a vN-improvement. We applied our method to noisy synthetic and field data recorded over a complex near-surface and we could pick more traces at far offsets. It was possible to accommodate more picks resulting in a better subsurface coverage

  12. Interactive Super Mario Bros Evolution

    DEFF Research Database (Denmark)

    Sørensen, Patrikk D.; Olsen, Jeppeh M.; Risi, Sebastian

    2016-01-01

    Creating controllers for NPCs in video games is traditionally a challenging and time consuming task. Automated learning methods such as neuroevolution (i.e. evolving artificial neural networks) have shown promise in this context but they often require carefully designed fitness functions to encou....... The results suggest that IEC is a viable alternative in designing complex controllers for video games that could be extended to other games in the future....

  13. Venus 2004: east and west elongations and solar transit

    Science.gov (United States)

    McKim, R. J.; Blaxall, K.; Heath, A.

    2007-04-01

    The year 2004 was exceptional in producing the first solar transit of Venus since the late Victorian era. The bright aureole and atmospheric ring were re-observed, and the entire phenomenon was witnessed for the first time ever in hydrogen alpha light. Although routine observations throughout 2004 were unexceptional, patterns of visibility of bright and dark markings, cusp extensions and cusp-caps were recorded. No correlation was found between the latitude of the sub-Earth point and the visibility of either cusp-cap, with the S. cap predominating for most of the year. It was possible to accurately follow individual ultraviolet dark markings over many consecutive rotations, extending from the E. to W. elongations, and thereby to make a current measurement of the synodic atmospheric rotation period for the near-equatorial features: 3.996 ± 0.001 days. The true Ashen Light was reported visually on only a few occasions, but these correspond closely to times when infrared emission from the surface of the dark side was recorded in 1-micron waveband images. Some of the stable dark side albedo features were also visible upon the 1-micron images, and have been tentatively identified with known surface features. Infrared imaging at the same waveband showed little detail on the sunlit disk, but a few bright spots were sufficiently well observed to suggest a synodic rotation period close to 5.0 days, not atypical for the lower cloud decks.

  14. APOBEC3G inhibits elongation of HIV-1 reverse transcripts.

    Directory of Open Access Journals (Sweden)

    Kate N Bishop

    2008-12-01

    Full Text Available APOBEC3G (A3G is a host cytidine deaminase that, in the absence of Vif, restricts HIV-1 replication and reduces the amount of viral DNA that accumulates in cells. Initial studies determined that A3G induces extensive mutation of nascent HIV-1 cDNA during reverse transcription. It has been proposed that this triggers the degradation of the viral DNA, but there is now mounting evidence that this mechanism may not be correct. Here, we use a natural endogenous reverse transcriptase assay to show that, in cell-free virus particles, A3G is able to inhibit HIV-1 cDNA accumulation not only in the absence of hypermutation but also without the apparent need for any target cell factors. We find that although reverse transcription initiates in the presence of A3G, elongation of the cDNA product is impeded. These data support the model that A3G reduces HIV-1 cDNA levels by inhibiting synthesis rather than by inducing degradation.

  15. Electrostatics Control Actin Filament Nucleation and Elongation Kinetics*

    Science.gov (United States)

    Crevenna, Alvaro H.; Naredi-Rainer, Nikolaus; Schönichen, André; Dzubiella, Joachim; Barber, Diane L.; Lamb, Don C.; Wedlich-Söldner, Roland

    2013-01-01

    The actin cytoskeleton is a central mediator of cellular morphogenesis, and rapid actin reorganization drives essential processes such as cell migration and cell division. Whereas several actin-binding proteins are known to be regulated by changes in intracellular pH, detailed information regarding the effect of pH on the actin dynamics itself is still lacking. Here, we combine bulk assays, total internal reflection fluorescence microscopy, fluorescence fluctuation spectroscopy techniques, and theory to comprehensively characterize the effect of pH on actin polymerization. We show that both nucleation and elongation are strongly enhanced at acidic pH, with a maximum close to the pI of actin. Monomer association rates are similarly affected by pH at both ends, although dissociation rates are differentially affected. This indicates that electrostatics control the diffusional encounter but not the dissociation rate, which is critical for the establishment of actin filament asymmetry. A generic model of protein-protein interaction, including electrostatics, explains the observed pH sensitivity as a consequence of charge repulsion. The observed pH effect on actin in vitro agrees with measurements of Listeria propulsion in pH-controlled cells. pH regulation should therefore be considered as a modulator of actin dynamics in a cellular environment. PMID:23486468

  16. Electrostatics control actin filament nucleation and elongation kinetics.

    Science.gov (United States)

    Crevenna, Alvaro H; Naredi-Rainer, Nikolaus; Schönichen, André; Dzubiella, Joachim; Barber, Diane L; Lamb, Don C; Wedlich-Söldner, Roland

    2013-04-26

    The actin cytoskeleton is a central mediator of cellular morphogenesis, and rapid actin reorganization drives essential processes such as cell migration and cell division. Whereas several actin-binding proteins are known to be regulated by changes in intracellular pH, detailed information regarding the effect of pH on the actin dynamics itself is still lacking. Here, we combine bulk assays, total internal reflection fluorescence microscopy, fluorescence fluctuation spectroscopy techniques, and theory to comprehensively characterize the effect of pH on actin polymerization. We show that both nucleation and elongation are strongly enhanced at acidic pH, with a maximum close to the pI of actin. Monomer association rates are similarly affected by pH at both ends, although dissociation rates are differentially affected. This indicates that electrostatics control the diffusional encounter but not the dissociation rate, which is critical for the establishment of actin filament asymmetry. A generic model of protein-protein interaction, including electrostatics, explains the observed pH sensitivity as a consequence of charge repulsion. The observed pH effect on actin in vitro agrees with measurements of Listeria propulsion in pH-controlled cells. pH regulation should therefore be considered as a modulator of actin dynamics in a cellular environment.

  17. Combining orthogonal polarization for elongated target detection with GPR

    International Nuclear Information System (INIS)

    Lualdi, Maurizio; Lombardi, Federico

    2014-01-01

    For an accurate imaging of ground penetrating radar data the polarization characteristics of the propagating electromagnetic (EM) wavefield and wave amplitude variations with antenna pattern orientation must be taken into account. For objects that show some directionality feature and cylindrical shape any misalignment between transmitter and target can strongly modify the polarization state of the backscattered wavefield, thus conditioning the detection capability of the system. Hints on the depolarization can be used to design the optimal GPR antenna survey to avoid omissions and pitfalls during data processing. This research addresses the issue of elongated target detection through a multi azimuth (or multi polarization) approach based on the combination of mutually orthogonal GPR data. Results from the analysis of the formal scattering problem demonstrate how this strategy can reach a scalar formulation of the scattering matrix and achieve a rotational invariant quantity. The effectiveness of the algorithm is then evaluated with a detailed field example showing results closely proximal to those obtained under the optimal alignment condition: detection is significantly improved and the risk of target missing is reduced. (paper)

  18. Is Quantum Gravity a Super-Quantum Theory?

    OpenAIRE

    Chang, Lay Nam; Lewis, Zachary; Minic, Djordje; Takeuchi, Tatsu

    2013-01-01

    We argue that quantum gravity should be a super-quantum theory, that is, a theory whose non-local correlations are stronger than those of canonical quantum theory. As a super-quantum theory, quantum gravity should display distinct experimentally observable super-correlations of entangled stringy states.

  19. Super-Resolution for Color Imagery

    Science.gov (United States)

    2017-09-01

    September 2017 2. REPORT TYPE Technical Report 3. DATES COVERED (From - To) 1 October 2016‒30 September 2017 4. TITLE AND SUBTITLE Super...slightly lighter shade of purple. There is slightly less purple coloring on the white paper than with the other 2 color spaces, and the black font is

  20. Super-Kamiokande worth full restoration

    CERN Multimedia

    Mishima, I

    2002-01-01

    While prospects are good that the SuperKamiokande facility will be partially repaired after an accident last November, the government has yet to confirm whether it will spend the estimated 2.5 billion yen needed for a full-scale restoration (1 page).

  1. 3D super-virtual refraction interferometry

    KAUST Repository

    Lu, Kai; AlTheyab, Abdullah; Schuster, Gerard T.

    2014-01-01

    Super-virtual refraction interferometry enhances the signal-to-noise ratio of far-offset refractions. However, when applied to 3D cases, traditional 2D SVI suffers because the stationary positions of the source-receiver pairs might be any place

  2. General super Virasoro construction on affine G

    International Nuclear Information System (INIS)

    Mohammedi, N.

    1990-10-01

    We consider a bosonic current algebra and a theory of free fermions and construct a general N = 1 super Virasoro current algebra. We obtain a master-set of equations which comprises the bosonic master equation for general Virasoro construction on affine G. As an illustration we study the case of the group SU(2). (author). 13 refs

  3. Conformal anomaly of super Wilson loop

    Energy Technology Data Exchange (ETDEWEB)

    Belitsky, A.V., E-mail: andrei.belitsky@asu.edu [Department of Physics, Arizona State University, Tempe, AZ 85287-1504 (United States)

    2012-09-11

    Classically supersymmetric Wilson loop on a null polygonal contour possesses all symmetries required to match it onto non-MHV amplitudes in maximally supersymmetric Yang-Mills theory. However, to define it quantum mechanically, one is forced to regularize it since perturbative loop diagrams are not well defined due to presence of ultraviolet divergences stemming from integration in the vicinity of the cusps. A regularization that is adopted by practitioners by allowing one to use spinor helicity formalism, on the one hand, and systematically go to higher orders of perturbation theory is based on a version of dimensional regularization, known as Four-Dimensional Helicity scheme. Recently it was demonstrated that its use for the super Wilson loop at one loop breaks both conformal symmetry and Poincare supersymmetry. Presently, we exhibit the origin for these effects and demonstrate how one can undo this breaking. The phenomenon is alike the one emerging in renormalization group mixing of conformal operators in conformal theories when one uses dimensional regularization. The rotation matrix to the diagonal basis is found by means of computing the anomaly in the Ward identity for the conformal boost. Presently, we apply this ideology to the super Wilson loop. We compute the one-loop conformal anomaly for the super Wilson loop and find that the anomaly depends on its Grassmann coordinates. By subtracting this anomalous contribution from the super Wilson loop we restore its interpretation as a dual description for reduced non-MHV amplitudes which are expressed in terms of superconformal invariants.

  4. Super-structure and building performance

    CSIR Research Space (South Africa)

    Van Wyk, Llewellyn V

    2010-11-01

    Full Text Available The super-structure consists predominantly of the load- and no-load-bearing walls-including all doors and windows and suspended floor slabs. The building envelope plays a significant role in the performance of a building, especially with regard...

  5. Single Image Super Resolution via Sparse Reconstruction

    NARCIS (Netherlands)

    Kruithof, M.C.; Eekeren, A.W.M. van; Dijk, J.; Schutte, K.

    2012-01-01

    High resolution sensors are required for recognition purposes. Low resolution sensors, however, are still widely used. Software can be used to increase the resolution of such sensors. One way of increasing the resolution of the images produced is using multi-frame super resolution algorithms.

  6. Super-renormalizable or finite Lee–Wick quantum gravity

    Directory of Open Access Journals (Sweden)

    Leonardo Modesto

    2016-08-01

    Full Text Available We propose a class of multidimensional higher derivative theories of gravity without extra real degrees of freedom besides the graviton field. The propagator shows up the usual real graviton pole in k2=0 and extra complex conjugates poles that do not contribute to the absorptive part of the physical scattering amplitudes. Indeed, they may consistently be excluded from the asymptotic observable states of the theory making use of the Lee–Wick and Cutkosky, Landshoff, Olive and Polkinghorne prescription for the construction of a unitary S-matrix. Therefore, the spectrum consists of the graviton and short lived elementary unstable particles that we named “anti-gravitons” because of their repulsive contribution to the gravitational potential at short distance. However, another interpretation of the complex conjugate pairs is proposed based on the Calmet's suggestion, i.e. they could be understood as black hole precursors long established in the classical theory. Since the theory is CPT invariant, the conjugate complex of the micro black hole precursor can be interpreted as a white hole precursor consistently with the 't Hooft complementarity principle. It is proved that the quantum theory is super-renormalizable in even dimension, i.e. only a finite number of divergent diagrams survive, and finite in odd dimension. Furthermore, turning on a local potential of the Riemann tensor we can make the theory finite in any dimension. The singularity-free Newtonian gravitational potential is explicitly computed for a range of higher derivative theories. Finally, we propose a new super-renormalizable or finite Lee–Wick standard model of particle physics.

  7. BREEDING SUPER-EARTHS AND BIRTHING SUPER-PUFFS IN TRANSITIONAL DISKS

    International Nuclear Information System (INIS)

    Lee, Eve J.; Chiang, Eugene

    2016-01-01

    The riddle posed by super-Earths (1–4R ⊕ , 2–20M ⊕ ) is that they are not Jupiters: their core masses are large enough to trigger runaway gas accretion, yet somehow super-Earths accreted atmospheres that weigh only a few percent of their total mass. We show that this puzzle is solved if super-Earths formed late, as the last vestiges of their parent gas disks were about to clear. This scenario would seem to present fine-tuning problems, but we show that there are none. Ambient gas densities can span many (in one case up to 9) orders of magnitude, and super-Earths can still robustly emerge after ∼0.1–1 Myr with percent-by-weight atmospheres. Super-Earth cores are naturally bred in gas-poor environments where gas dynamical friction has weakened sufficiently to allow constituent protocores to gravitationally stir one another and merge. So little gas is present at the time of core assembly that cores hardly migrate by disk torques: formation of super-Earths can be in situ. The basic picture—that close-in super-Earths form in a gas-poor (but not gas-empty) inner disk, fed continuously by gas that bleeds inward from a more massive outer disk—recalls the largely evacuated but still accreting inner cavities of transitional protoplanetary disks. We also address the inverse problem presented by super-puffs: an uncommon class of short-period planets seemingly too voluminous for their small masses (4–10R ⊕ , 2–6M ⊕ ). Super-puffs most easily acquire their thick atmospheres as dust-free, rapidly cooling worlds outside ∼1 AU where nebular gas is colder, less dense, and therefore less opaque. Unlike super-Earths, which can form in situ, super-puffs probably migrated in to their current orbits; they are expected to form the outer links of mean-motion resonant chains, and to exhibit greater water content. We close by confronting observations and itemizing remaining questions

  8. BREEDING SUPER-EARTHS AND BIRTHING SUPER-PUFFS IN TRANSITIONAL DISKS

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eve J.; Chiang, Eugene, E-mail: evelee@berkeley.edu, E-mail: echiang@astro.berkeley.edu [Department of Astronomy, University of California Berkeley, Berkeley, CA 94720-3411 (United States)

    2016-02-01

    The riddle posed by super-Earths (1–4R{sub ⊕}, 2–20M{sub ⊕}) is that they are not Jupiters: their core masses are large enough to trigger runaway gas accretion, yet somehow super-Earths accreted atmospheres that weigh only a few percent of their total mass. We show that this puzzle is solved if super-Earths formed late, as the last vestiges of their parent gas disks were about to clear. This scenario would seem to present fine-tuning problems, but we show that there are none. Ambient gas densities can span many (in one case up to 9) orders of magnitude, and super-Earths can still robustly emerge after ∼0.1–1 Myr with percent-by-weight atmospheres. Super-Earth cores are naturally bred in gas-poor environments where gas dynamical friction has weakened sufficiently to allow constituent protocores to gravitationally stir one another and merge. So little gas is present at the time of core assembly that cores hardly migrate by disk torques: formation of super-Earths can be in situ. The basic picture—that close-in super-Earths form in a gas-poor (but not gas-empty) inner disk, fed continuously by gas that bleeds inward from a more massive outer disk—recalls the largely evacuated but still accreting inner cavities of transitional protoplanetary disks. We also address the inverse problem presented by super-puffs: an uncommon class of short-period planets seemingly too voluminous for their small masses (4–10R{sub ⊕}, 2–6M{sub ⊕}). Super-puffs most easily acquire their thick atmospheres as dust-free, rapidly cooling worlds outside ∼1 AU where nebular gas is colder, less dense, and therefore less opaque. Unlike super-Earths, which can form in situ, super-puffs probably migrated in to their current orbits; they are expected to form the outer links of mean-motion resonant chains, and to exhibit greater water content. We close by confronting observations and itemizing remaining questions.

  9. Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs

    Directory of Open Access Journals (Sweden)

    Victoria A. Church

    2017-09-01

    Full Text Available The cellular abundance of mature microRNAs (miRNAs is dictated by the efficiency of nuclear processing of primary miRNA transcripts (pri-miRNAs into pre-miRNA intermediates. The Microprocessor complex of Drosha and DGCR8 carries this out, but it has been unclear what controls Microprocessor’s differential processing of various pri-miRNAs. Here, we show that Drosophila DGCR8 (Pasha directly associates with the C-terminal domain of the RNA polymerase II elongation complex when it is phosphorylated by the Cdk9 kinase (pTEFb. When association is blocked by loss of Cdk9 activity, a global change in pri-miRNA processing is detected. Processing of pri-miRNAs with a UGU sequence motif in their apical junction domain increases, while processing of pri-miRNAs lacking this motif decreases. Therefore, phosphorylation of RNA polymerase II recruits Microprocessor for co-transcriptional processing of non-UGU pri-miRNAs that would otherwise be poorly processed. In contrast, UGU-positive pri-miRNAs are robustly processed by Microprocessor independent of RNA polymerase association.

  10. SuperB A High-Luminosity Asymmetric $e^+ e^-$ Super Flavour Factory : Conceptual Design Report

    CERN Document Server

    Bona, M.; Grauges Pous, E.; Colangelo, P.; De Fazio, F.; Palano, A.; Manghisoni, M.; Re, V.; Traversi, G.; Eigen, G.; Venturini, M.; Soni, N.; Bruschi, M.; De Castro, S.; Faccioli, P.; Gabrieli, A.; Giacobbe, B.; Semprini Cesare, N.; Spighi, R.; Villa, M.; Zoccoli, A.; Hearty, C.; McKenna, J.; Soni, A.; Khan, A.; Barniakov, A.Y.; Barniakov, M.Y.; Blinov, V.E.; Druzhinin, V.P.; Golubev, V.B.; Kononov, S.A.; Koop, I.A.; Kravchenko, E.A.; Levichev, E.B.; Nikitin, S.A.; Onuchin, A.P.; Piminov, P.A.; Serednyakov, S.I.; Shatilov, D.N.; Skovpen, Y.I.; Solodov, E.A.; Cheng, C.H.; Echenard, B.; Fang, F.; Hitlin, D.J.; Porter, F.C.; Asner, D.M.; Pham, T.N.; Fleischer, R.; Giudice, G.F.; Hurth, T.; Mangano, M.; Mancinelli, G.; Meadows, B.T.; Schwartz, A.J.; Sokoloff, M.D.; Soffer, A.; Beard, C.D.; Haas, T.; Mankel, R.; Hiller, G.; Ball, P.; Pappagallo, M.; Pennington, M.R.; Gradl, W.; Playfer, S.; Abada, A.; Becirevic, D.; Descotes-Genon, S.; Pene, O.; Andreotti, D.; Andreotti, M.; Bettoni, D.; Bozzi, C.; Calabresi, R.; Cecchi, A.; Cibinetto, G.; Franchini, P.; Luppi, E.; Negrini, M.; Petrella, A.; Piemontese, L.; Prencipe, E.; Santoro, V.; Stancari, G.; Anulli, F.; Baldini-Ferroli, R.; Biagini, M.E.; Boscolo, M.; Calcaterra, A.; Drago, A.; Finocchiaro, G.; Guiducci, S.; Isidori, G.; Pacetti, S.; Patteri, P.; Peruzzi, I.M.; Piccolo, M.; Preger, M.A.; Raimondi, P.; Rama, M.; Vaccarezza, C.; Zallo, A.; Zobov, M.; De Sangro, R.; Buzzo, A.; Lo Vetere, M.; Macri, M.; Monge, M.R.; Passaggio, S.; Patrignani, C.; Robutti, E.; Tosi, S.; Matias, J.; Panduro Vazquez, W.; Borzumati, F.; Eyges, V.; Prell, S.A.; Pedlar, T.K.; Korpar, S.; Pestonik, R.; Staric, M.; Neubert, M.; Denig, A.G.; Nierste, U.; Agoh, T.; Ohmi, K.; Ohnishi, Y.; Fry, J.R.; Touramanis, C.; Wolski, A.; Golob, B.; Krizan, P.; Flaecher, H.; Bevan, A.J.; Di Lodovico, F.; George, K.A.; Barlow, R.; Lafferty, G.; Jawahery, A.; Roberts, D.A.; Simi, G.; Patel, P.M.; Robertson, S.H.; Lazzaro, A.; Palombo, F.; Kaidalov, A.; Buras, A.J.; Tarantino, C.; Buchalla, G.; Sanda, A.I.; D'Ambrosio, G.; Ricciardi, G.; Bigi, I.; Jessop, C.P.; Losecco, J.M.; Honscheid, K.; Arnaud, N.; Chehab, R.; Fedala, Y.; Polci, F.; Roudeau, P.; Sordini, V.; Soskov, V.; Stocchi, A.; Variola, A.; Vivoli, A.; Wormser, G.; Zomer, F.; Bertolin, A.; Brugnera, R.; Gagliardi, N.; Gaz, A.; Margoni, M.; Morandin, M.; Posocco, M.; Rotondo, M.; Simonetto, F.; Stroili, R.; Bonneaud, G.R.; Lombardo, V.; Calderini, G.; Ratti, L.; Speziali, V.; Biasini, M.; Covarelli, R.; Manoni, E.; Servoli, L.; Angelini, C.; Batignani, G.; Bettarini, S.; Bosi, F.; Carpinelli, M.; Cenci, R.; Cervelli, A.; Dell'Orso, M.; Forti, F.; Giannetti, P.; Giorgi, M.; Lusiani, A.; Marchiori, G.; Massa, M.; Mazur, M.A.; Morsani, F.; Neri, N.; Paoloni, E.; Raffaelli, F.; Rizzo, G.; Walsh, J.; Braun, V.; Lenz, A.; Adams, G.S.; Danko, I.Z.; Baracchini, E.; Bellini, F.; Cavoto, G.; D'Orazio, A.; Del Re, D.; Di Marco, E.; Faccini, R.; Ferrarotto, F.; Gaspero, Mario; Jackson, P.; Martinelli, G.; Mazzoni, M.A.; Morganti, Silvio; Piredda, G.; Renga, F.; Silvestrini, L.; Voena, C.; Catani, L.; Di Ciaccio, A.; Messi, R.; Santovetti, E.; Satta, A.; Ciuchini, M.; Lubicz, V.; Wilson, F.F.; Godang, R.; Chen, X.; Liu, H.; Park, W.; Purohit, M.; Trivedi, A.; White, R.M.; Wilson, J.R.; Allen, M.T.; Aston, D.; Bartoldus, R.; Brodsky, S.J.; Cai, Y.; Coleman, J.; Convery, M.R.; DeBarger, S.; Dingfelder, J.C.; Dubois-Felsmann, G.P.; Ecklund, S.; Fisher, A.S.; Haller, G.; Heifets, S.A.; Kaminski, J.; Kelsey, M.H.; Kocian, M.L.; Leith, D.W.G.S.; Li, N.; Luitz, S.; Luth, V.; MacFarlane, D.; Messner, R.; Muller, D.R.; Nosochkov, Y.; Novokhatski, A.; Pivi, M.; Ratcliff, B.N.; Roodman, A.; Schwiening, J.; Seeman, J.; Snyder, A.; Sullivan, M.; Va'Vra, J.; Wienands, U.; Wisniewski, W.; Stoeck, H.; Cheng, H.Y.; Li, H.N.; Keum, Y.Y.; Gronau, M.; Grossman, Y.; Bianchi, F.; Gamba, D.; Gambino, P.; Marchetto, F.; Menichetti, Ezio A.; Mussa, R.; Pelliccioni, M.; Dalla Betta, G.F.; Bomben, M.; Bosisio, L.; Cartaro, C.; Lanceri, L.; Vitale, L.; Azzolini, V.; Bernabeu, J.; Lopez-March, N.; Martinez-Vidal, F.; Milanes, D.A.; Oyanguren, A.; Paradisi, P.; Pich, A.; Sanchis-Lozano, M.A.; Kowalewski, Robert V.; Roney, J.M.; Back, J.J.; Gershon, T.J.; Harrison, P.F.; Latham, T.E.; Mohanty, G.B.; Petrov, A.A.; Pierini, M.; INFN

    2007-01-01

    The physics objectives of SuperB, an asymmetric electron-positron collider with a luminosity above 10^36/cm^2/s are described, together with the conceptual design of a novel low emittance design that achieves this performance with wallplug power comparable to that of the current B Factories, and an upgraded detector capable of doing the physics in the SuperB environment.

  11. The 2015 super-resolution microscopy roadmap

    International Nuclear Information System (INIS)

    Hell, Stefan W; Sahl, Steffen J; Bates, Mark; Jakobs, Stefan; Zhuang, Xiaowei; Heintzmann, Rainer; Booth, Martin J; Bewersdorf, Joerg; Shtengel, Gleb; Hess, Harald; Tinnefeld, Philip; Honigmann, Alf; Testa, Ilaria; Cognet, Laurent; Lounis, Brahim; Ewers, Helge; Davis, Simon J; Eggeling, Christian; Klenerman, David; Willig, Katrin I

    2015-01-01

    Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly with respect to the study of living cells and organisms. Unfortunately, the applicability of the optical microscope is limited, since the diffraction of light imposes limitations on the spatial resolution of the image. Consequently the details of, for example, cellular protein distributions, can be visualized only to a certain extent. Fortunately, recent years have witnessed the development of ‘super-resolution’ far-field optical microscopy (nanoscopy) techniques such as stimulated emission depletion (STED), ground state depletion (GSD), reversible saturated optical (fluorescence) transitions (RESOLFT), photoactivation localization microscopy (PALM), stochastic optical reconstruction microscopy (STORM), structured illumination microscopy (SIM) or saturated structured illumination microscopy (SSIM), all in one way or another addressing the problem of the limited spatial resolution of far-field optical microscopy. While SIM achieves a two-fold improvement in spatial resolution compared to conventional optical microscopy, STED, RESOLFT, PALM/STORM, or SSIM have all gone beyond, pushing the limits of optical image resolution to the nanometer scale. Consequently, all super-resolution techniques open new avenues of biomedical research. Because the field is so young, the potential capabilities of different super-resolution microscopy approaches have yet to be fully explored, and uncertainties remain when considering the best choice of methodology. Thus, even for experts, the road to the future is sometimes shrouded in mist. The super-resolution optical microscopy roadmap of Journal of Physics D: Applied Physics addresses this need for clarity. It provides guidance to the outstanding questions through a collection of short review articles from experts in the field, giving a thorough

  12. The sl (2 n|2 n) (1) super-Toda lattices and the heavenly equations as continuum limit

    International Nuclear Information System (INIS)

    Kuznetsova, Zhanna; Popowicz, Ziemowit; Toppan, Francesco.

    2005-04-01

    The n → ∞ continuum limit of super-Toda models associated with the affine sl (2 n|2 n) (1) (super)algebra series produces (2 + 1)-dimensional integrable equations in the S 1 versus R 2 spacetimes. The equations of motion of the (super)Toda hierarchies depend not only on the chosen (super)algebras but also on the specific presentation of their Cartan matrices. Four distinct series of integrable hierarchies in relation with symmetric-versus-antisymmetric, null-versus-non null presentations of the corresponding Cartan matrices are investigated. In the continuum limit we derive four classes of integrable equations of heavenly type, generalizing the results previously obtained in the literature. The systems are manifestly N = 1 supersymmetric and, for specific choices of the Cartan matrix preserving the complex structure, admit a hidden N = 2 supersymmetry. The coset reduction of the (super)-heavenly equation to the I versus R (2) (S 1 /Z 2 ) versus R 2 spacetime (with I a line segment) is illustrated. Finally, integrable N = 2,4 super symmetrically extended models in (1 + 1) dimensions are constructed through dimensional reduction of the previous systems. (author)

  13. Experimental results on elongation control using dynamic input allocation at FTU

    International Nuclear Information System (INIS)

    Varano, G.; Boncagni, L.; Galeani, S.; Granucci, G.; Vitale, V.; Zaccarian, L.

    2011-01-01

    We report on the experimental results related to a recently proposed control scheme for the regulation of plasma elongation using the poloidal field coils available at FTU, already used for the horizontal position control. The proposed technique allows to realize elongation regulation as a secondary task using the same poloidal coils.

  14. Experimental and mathematical methods for representing relative surface elongation of the ACL

    NARCIS (Netherlands)

    Pioletti, D. P.; Heegaard, J. H.; Rakotomanana, R. L.; Leyvraz, P. F.; Blankevoort, L.

    1995-01-01

    The common approach to assess the stabilizing role of the ACL in the knee has been to measure the elongation of a few marked fibers in the ligament. A comparison of the relative elongation (RE) of these marked fibers between different specimens and studies is delicate due to the difficulty of

  15. Influence of Gradual Elongation to the Patella Tendon Insertion in Rabbits

    Directory of Open Access Journals (Sweden)

    Hirotaka Mutsuzaki

    2014-08-01

    Full Text Available The purpose of this study was to examine the histological changes at the patella tendon (PT insertion site under gradual elongation in rabbits. Gradual elongation of the PT was performed using external fixation for 4 weeks, with a lengthening speed of 0.5 mm/day (elongation group; n = 24. Rabbits in the sham group underwent the same surgical procedure without gradual elongation (sham group; n = 24. Eight animals were sacrificed 1, 2 and 4 weeks after surgery in each group, respectively. Average thicknesses of stained glycosaminoglycan (GAGs areas by Safranin-O staining in the total cartilage layer and the uncalcified fibrocartilage layer in the elongation group were significantly higher than that in the sham group at 4 weeks (p < 0.05 and that in the intact PT group (n = 6, p < 0.05. In the elongation group, the peak in the average thicknesses of the stained GAGs areas in the total cartilage layer and the uncalcified fibrocartilage layer were observed at 4 weeks. Gradual elongation of PT insertion significantly affected the increase in the average thicknesses of the stained GAGs areas in the cartilage layer especially in the uncalcified fibrocartilage layer at 4 weeks in rabbits. Clinically, insertions of tendon and ligament can extend during gradual elongation using external fixation more than 4 weeks after the operation.

  16. Methanol as an alternative electron donor in chain elongation for butyrate and caproate formation

    NARCIS (Netherlands)

    Chen, W.S.; Ye, Y.; Steinbusch, K.J.J.; Strik, D.P.B.T.B.; Buisman, C.J.N.

    2016-01-01

    Chain elongation is an emerging mixed culture biotechnology converting acetate into valuable biochemicals by using ethanol as an external electron donor. In this study we proposed to test another potential electron donor, methanol, in chain elongation. Methanol can be produced through the

  17. The Solution Construction of Heterotic Super-Liouville Model

    Science.gov (United States)

    Yang, Zhan-Ying; Zhen, Yi

    2001-12-01

    We investigate the heterotic super-Liouville model on the base of the basic Lie super-algebra Osp(1|2).Using the super extension of Leznov-Saveliev analysis and Drinfeld-Sokolov linear system, we construct the explicit solution of the heterotic super-Liouville system in component form. We also show that the solutions are local and periodic by calculating the exchange relation of the solution. Finally starting from the action of heterotic super-Liouville model, we obtain the conserved current and conserved charge which possessed the BRST properties.

  18. Detecting Water on Super-Earths Using JAVST

    Science.gov (United States)

    Deming, D.

    2010-01-01

    Nearby lower train sequence stars host a class of planets known as Super-Earths, that have no analog in our own solar system. Super-Earths are rocky and/or icy planets with masses up to about 10 Earth masses, They are expected to host atmospheres generated by a number of processes including accretion of chondritic material. Water vapor should be a common constituent of super-Earth atmospheres, and may be detectable in transiting super-Earths using transmission spectroscopy during primar y eclipse, and emission spectroscopy at secondary eclipse. I will discuss the prospects for super-Earth atmospheric measurements using JWST.

  19. Microgravity experiments on a granular gas of elongated grains

    Science.gov (United States)

    Harth, K.; Trittel, T.; Kornek, U.; Höme, S.; Will, K.; Strachauer, U.; Stannarius, R.

    2013-06-01

    Granular gases represent well-suited systems to investigate statistical granular dynamics. The literature comprises numerous investigations of ensembles of spherical or irregularly shaped grains. Mainly computer models, analytical theories and experiments restricted to two dimensions were reported. In three-dimensions, the gaseous state can only be maintained by strong external excitation, e. g. vibrations or electro-magnetic fields, or in microgravity. A steady state, where the dynamics of a weakly disturbed granular gas are governed by particle-particle collisions, is hard to realize with spherical grains due to clustering. We present the first study of a granular gas of elongated cylinders in three dimensions. The mean free path is considerably reduced with respect to spheres at comparable filling fractions. The particles can be tracked in 3D over a sequence of frames. In a homogeneous steady state, we find non-Gaussian velocity distributions and a lack of equipartition of kinetic energy. We discuss the relations between energy input and vibrating plate accelerations. At the request of the authors and the Proceedings Editors, the PDF file of this article has been updated to amend some references present in the PDF file submitted to AIP Publishing. The references affected are listed here:[1] (c) K. Nichol and K. E. Daniels, Phys. Rev. Lett. 108, 018001 (2012); [11] (e) P. G. de Gennes and J. Prost, The Physics of Liquid Crystals, Clarendon Press, Oxford (1993); [17] (b) K. Harth, et al., Phys. Rev. Lett. 110, 144102 (2013).A LaTeX processing error resulted in changes to the authors reference formatting, which was not detected prior to publication. Due apologies are given to the authors for this oversight. The updated article PDF was published on 12 August 2013.

  20. Germination and root elongation bioassays in six different plant species for testing Ni contamination in soil.

    Science.gov (United States)

    Visioli, Giovanna; Conti, Federica D; Gardi, Ciro; Menta, Cristina

    2014-04-01

    In vitro short-term chronic phytotoxicity germination and root elongation test were applied to test the effects of nickel (Ni) in seed germination and root elongation in six plants species: Cucumis sativus (Cucurbitaceae), Lepidium sativum and Brassica nigra (Brassicaceae), Trifolium alexandrinum and Medicago sativa (Fabaceae), Phacelia tanacetifolia (Boraginaceae). A naturally Ni rich soil was used to compare the results obtained. Unlike root elongation, germination was not affected by Ni in any of the six species tested. EC50 values, calculated on the root elongation, showed that Ni toxicity decreases in the following order: P. tanacetifolia > B. nigra > C. sativus > L. sativum > M. sativa > T. alexandrinum. The test conducted using soil elutriate revealed a significantly lower effect in both seed germination and root elongation when compared to the results obtained using untreated soil. Conversely, the test performed on soil confirmed the high sensitivity of C. sativus, P. tanacetifolia and L. sativum to Ni.

  1. Restricted cell elongation in Arabidopsis hypocotyls is associated with a reduced average pectin esterification level.

    Science.gov (United States)

    Derbyshire, Paul; McCann, Maureen C; Roberts, Keith

    2007-06-17

    Cell elongation is mainly limited by the extensibility of the cell wall. Dicotyledonous primary (growing) cell walls contain cellulose, xyloglucan, pectin and proteins, but little is known about how each polymer class contributes to the cell wall mechanical properties that control extensibility. We present evidence that the degree of pectin methyl-esterification (DE%) limits cell growth, and that a minimum level of about 60% DE is required for normal cell elongation in Arabidopsis hypocotyls. When the average DE% falls below this level, as in two gibberellic acid (GA) mutants ga1-3 and gai, and plants expressing pectin methyl-esterase (PME1) from Aspergillus aculeatus, then hypocotyl elongation is reduced. Low average levels of pectin DE% are associated with reduced cell elongation, implicating PMEs, the enzymes that regulate DE%, in the cell elongation process and in responses to GA. At high average DE% other components of the cell wall limit GA-induced growth.

  2. Effect of disulfide and sulfhydryl reagents on abortive and productive elongation catalyzed by ''Escheridia coli'' RNA polymerase

    International Nuclear Information System (INIS)

    Radlowski, M.; Job, D.

    1994-01-01

    The effect of disulfide and sulfhydryl reagents on the rate of abortive and productive elongation has been studied using ''Escherichia coli'' RNA polymerase holoenzyme and poly[d(A-T)] as template. In the presence of UTP as a single substrate and UpA as a primer, the enzyme catalyzed efficiently the synthesis of the trinucleotide product UpApU. Incubation of RNA polymerase with 1 mM 2-mercaptoethanol resulted in a 5-fold increase of the rate of UpApU synthesis. In contrast, incubation of the enzyme with 1 mM 5,5'-dithio-bis(2-nitrobenzoic) acid resulted in a 6-fold decrease of the rate of abortive elongation. Determination of the steady state kinetic constants associated with UpApU synthesis disclosed that the disulfide and sulfhydryl reagents mainly affected the rate of UpApU release from the ternary transcription complexes and therefore influenced the stability of such complexes. (author). 15 refs, 1 fig., 1 tab

  3. Disentangling the Trichoderma viridescens complex

    NARCIS (Netherlands)

    Jaklitsch, W.M.; Samuels, G.J.; Ismaiel, A.; Voglmayr, H.

    2013-01-01

    Trichoderma viridescens is recognised as a species complex. Multigene analyses based on the translation elongation factor 1-alpha encoding gene (tef1), a part of the rpb2 gene, encoding the second largest RNA polymerase subunit and the larger subunit of ATP citrate lyase (acl1) reveals 13

  4. Surgical Thoracic Transplant Training: Super Fellowship-Is It Super?

    Science.gov (United States)

    Makdisi, George; Makdisi, Tony; Caldeira, Christiano C; Wang, I-Wen

    2017-10-11

    The quality of training provided to thoracic transplant fellows is a critical step in the care of complex patients undergoing transplant. The training varies since it is not an accreditation council for graduate medical education accredited fellowship. A total of 104 heart or lung transplant program directors throughout the United States were sent a survey of 24 questions focusing on key aspects of training, fellowship training content and thoracic transplant job satisfaction. Out of the 104 programs surveyed 45 surveys (43%) were returned. In total, 26 programs offering a transplant fellowship were included in the survey. Among these programs 69% currently have fellows of which 56% are American Board of Thoracic Surgery board eligible. According to the United Network for Organ Sharing (UNOS) requirements, 46% of the programs do not meet the requirements to be qualified as a primary heart transplant surgeon. A total of 23% of lung transplant programs also perform less than the UNOS minimum requirements. Only 24% have extra-surgical curriculum. Out of the participating programs, only 38% of fellows secured a job in a hospital setting for performing transplants. An astounding 77% of replies site an unpredictable work schedule as the main reason that makes thoracic transplant a less than favorable profession among new graduates. Long hours were also a complaint of 69% of graduates who agreed that their personal life is affected by excessive work hours. Annually, almost half of all thoracic transplant programs perform fewer than the UNOS requirements to be a primary thoracic surgeon. This results in a majority of transplant fellows not finding a suitable transplant career. The current and future needs for highly qualified thoracic transplant surgeons will not be met through our existing training mechanisms. Copyright © 2017 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  5. Superstring field theories on super-flag manifolds: superdiff S1/S1 and superdiff S1/super S1

    International Nuclear Information System (INIS)

    Zhao Zhiyong; Wu, Ke; Saito, Takesi

    1987-01-01

    We generalize the geometric approach of Bowick and Rajeev [BR] to superstring field theories. The anomaly is identified with nonvanishing of the Ricci curvature of the super-flag manifold. We explicitly calculate the curvatures of superdiff S 1 /S 1 and superdiff S 1 /superS 1 using super-Toeplitz operator techniques. No regularization is needed in this formalism. The critical dimension D=10 is rediscovered as a result of vanishing curvature of the product bundle over the super-flag manifold. (orig.)

  6. N=1 supersymmetry and super quantum electrodynamic in Atiyah-Ward space-time

    International Nuclear Information System (INIS)

    Andrade, M.A. de; Cima, O.M. Del; Magalhaes, M.N.P.

    1994-12-01

    The supersymmetric gauge invariant action for the massive Abelian N=1 super-QED 2+2 in the Atiyah-Ward space-time (D=2+2) is formulated. The questions concerning the scheme of the gauge invariance in D=2+2 by means of gauging the massive N=1 super-QED 2+2 are investigated. It is studied how to ensure the gauge invariance at the expenses of the introduction of a complex vector superfield. It is discussed the Wess-Zumino gauge and thereupon we conclude that in this gauge, only the imaginary part of the complex vector field, B μ , gauges a U(1)-symmetry, whereas its real part gauges a Weyl symmetry. It is build up the gauge invariant massive term by introducing four scalar superfields: a pair of chiral and a pair of anti-chiral superfields; the supermultiplets of each pair have opposite U (1)-changes. It is carried out a dimensional reduction a la Scherk of the massive N=1 super-QED 2+2 action from D=2+2 to D=1+2. Truncations are needed in order to suppress unphysical modes and one ends up with a parity-preserving N=1 super QED 1+2 (rather than N=2) in D=1+2 which spectrum is free from tachyons and ghosts at tree-level. Finally it is show that the N=1 super-QED 1+2 obtained is the supersymmetry version of the φ3 QED. (author). 27 refs

  7. N=1 supersymmetry and super quantum electrodynamic in Atiyah-Ward space-time

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, M.A. de; Cima, O.M. Del; Magalhaes, M.N.P.

    1994-12-01

    The supersymmetric gauge invariant action for the massive Abelian N=1 super-QED{sub 2+2} in the Atiyah-Ward space-time (D=2+2) is formulated. The questions concerning the scheme of the gauge invariance in D=2+2 by means of gauging the massive N=1 super-QED{sub 2+2} are investigated. It is studied how to ensure the gauge invariance at the expenses of the introduction of a complex vector superfield. It is discussed the Wess-Zumino gauge and thereupon we conclude that in this gauge, only the imaginary part of the complex vector field, B{sub {mu}}, gauges a U(1)-symmetry, whereas its real part gauges a Weyl symmetry. It is build up the gauge invariant massive term by introducing four scalar superfields: a pair of chiral and a pair of anti-chiral superfields; the supermultiplets of each pair have opposite U (1)-changes. It is carried out a dimensional reduction a la Scherk of the massive N=1 super-QED{sub 2+2} action from D=2+2 to D=1+2. Truncations are needed in order to suppress unphysical modes and one ends up with a parity-preserving N=1 super QED{sub 1+2} (rather than N=2) in D=1+2 which spectrum is free from tachyons and ghosts at tree-level. Finally it is show that the N=1 super-QED{sub 1+2} obtained is the supersymmetry version of the {sub {phi}3} QED. (author). 27 refs.

  8. Solar neutrinos at super-Kamiokande

    International Nuclear Information System (INIS)

    Inoue, K.

    1999-01-01

    A huge ring imaging water Cherenkov detector, super-Kamiokande, has started data accumulation on April 1st, 1996 as promised. This experiment is expected to give a definite answer to the neutrino oscillation solutions of the long standing solar neutrino problem through high statistics and high precision spectrum and day/night flux measurement. Super-Kamiokande is accumulating 8 B solar neutrino data very quickly and preliminary results obtained from 374 days of data are presented here, instead of 306 days of data presented at the conference. No significant day/night variation nor seasonal variation are found. Systematic errors of energy scale are largely reduced by the LINAC calibrations at various positions. And the experiment is getting closer to the level of the systematic errors where we can definitely discuss about the spectrum distortion. Also implications of those preliminary results are discussed within two neutrino oscillation hypothesis

  9. Low background techniques for SuperNEMO

    International Nuclear Information System (INIS)

    Liu, Xin Ran; Mott, James

    2015-01-01

    The UK contribution to achieving the ultra-low background conditions required inside the detectors of the SuperNEMO experiment are described. A dedicated facility has been established for the screening and selection of materials through gamma ray spectroscopy using germanium detectors. Initial results from two detectors are shown. The radon level inside the SuperNEMO detector must be less than 150 μBq/m 3 in order to achieve the target sensitivity. A Radon Concentration Line (RnCL) has been developed capable of measuring radon levels in large gas volumes down to 5 μBq/m 3 , improving on standard state-of-the-art radon detectors by 3 orders of magnitude. The development, commissioning and first measurements of radon content using the RnCL are also presented. (paper)

  10. The geometry of the super KP flows

    International Nuclear Information System (INIS)

    Rabin, J.M.

    1991-01-01

    A supersymmetric generalization of the Krichever map is used to construct algebro-geometric solutions to the various super Kadomtsev-Petviashvili (SKP) hierarchies. The geometric data required consist of a suitable algebraic supercurve of genus g (generally not a super Riemann surface) with a distinguished point and local coordinates (z, θ) there, and a generic line bundle of degree g-1 with a local trivialization near the point. The resulting solutions to the Manin-Radul SKP system describe coupled deformations of the line bundle and the supercurve itself, in contrast to the ordinary KP system which deforms line bundles but not curves. Two new SKP systems are introduced: An integrable 'Jacobian' system whose solutions describe genuine Jacobian flows, deforming the bundle but not the curve; and a nonintegrable 'maximal' system describing independent deformations of bundle and curve. The Kac-van de Leur SKP system describes the same deformations as the maximal system, but in a different parametrization. (orig.)

  11. Non-standard quantum groups and superization

    Energy Technology Data Exchange (ETDEWEB)

    Majid, S. [Cambridge Univ. (United Kingdom). Dept. of Applied Mathematics and Theoretical Physics (DAMTP); Rodriguez-Plaza, M.J. [Nationaal Inst. voor Kernfysica en Hoge-Energiefysica (NIKHEF), Amsterdam (Netherlands). Sectie H

    1995-12-31

    We obtain the universal R-matrix of the non-standard quantum group associated to the Alexander-Conway knot polynomial. We show further that this nonstandard quantum group is related to the super-quantum group U{sub q}gl(1 vertical stroke 1) by a general process of superization, which we describe. We also study a twisted variant of this non-standard quantum group and obtain, as a result, a twisted version uf U{sub q}gl(1 vertical stroke 1) as a q-supersymmetry of the exterior differential calculus of any quantum plane of Hecke type, acting by mixing the bosonic x{sub i} co-ordinates and the forms dx{sub i}. (orig.).

  12. Pulsating stars in SuperWASP

    Directory of Open Access Journals (Sweden)

    Holdsworth Daniel L.

    2017-01-01

    Full Text Available SuperWASP is one of the largest ground-based surveys for transiting exoplanets. To date, it has observed over 31 million stars. Such an extensive database of time resolved photometry holds the potential for extensive searches of stellar variability, and provide solid candidates for the upcoming TESS mission. Previous work by e.g. [15], [5], [12] has shown that the WASP archive provides a wealth of pulsationally variable stars. In this talk I will provide an overview of the SuperWASP project, present some of the published results from the survey, and some of the on-going work to identify key targets for the TESS mission.

  13. Experiments at high elongations in DIII-D

    International Nuclear Information System (INIS)

    Lazarus, E.A.; Turnbull, A.D.; Kellman, A.G.; Ferron, J.R.; Helton, F.J.; Lao, L.L.; Leuer, J.A.; Strait, E.J.; Taylor, T.S.

    1990-01-01

    In this paper we discuss the limitation to elongation observed in D-shaped plasmas in the DIII-D tokamak. We find that as the triangularity is increased and ell i is decreased that the n = O mode takes on an increasingly non-rigid character. Our analysis shows two aspects of the behavior: first, an increasing variation of the m/n = 1/0 component across flux surfaces and second, an increase in the relative amplitude of a m/n = 3/0 component which couples to the m/n = 1/0 component and further destabilizes the mode. In previous work we have reported on study of vertical control and the implementation of those results on DIII-D. In that study we used a single filament, with properties consistent with the radial force balance, to represent the plasma and employed an eigenmode description of the passive shell in order to allow time-ordering of the problem. The most important result of this study was that the active control coil must be positioned in the poloidal plane so as to minimize its interaction with the stabilizing shell currents. As a consequence of plasma toroidicity, these currents flow primarily in the outboard regions of the shell. Thus, control coils on the inboard side of the shell, near the midplane, are required. With such a spatial arrangement we can have radial fields from the active coil penetrating the shell on a time scale faster than the decay of the stabilizing shell currents. In accordance with these model calculations the control system for DIII-D tokamak has been modified resulting in operation to within a few percent of the ideal MHD limit for axisymmetric stability. In this work we refer to the ideal MHD limit as that of the plasma-shell system. The ideal limit can actually be reduced by a poor choice of the active control coils, however that is not the case for work discussed here. 7 refs., 6 figs

  14. Current drive by Alfven waves in elongated cross section tokamak

    International Nuclear Information System (INIS)

    Tsypin, V.S.; Elfimov, A.G.; Nekrasov, F.M.; Azevedo, C.A.; Assis, A.S. de

    1997-01-01

    Full text. The problem of the noninductive current drive in cylindrical plasma model and in circular cross-section tokamaks had been already discussed intensively. At the beginning of the study of this problem it have been clear that there are significant difficulties in using of the current-drive in toroidal magnetic traps, especially in a tokamak reactor. Thus, in the case of the lower-hybrid current-drive the efficiency of this current-drive drops strongly as the plasma density increases. For the Alfven waves, there is an opinion that the efficiency of the current-drive drops as a result of waves absorption by the trapped particles 1,2. Okhawa proposed that the current in a magnetized plasma can be maintained also by means of forces, depending on the radiofrequency (rf) field amplitude gradients (the helicity injection). This idea was developed later, some new hopes appeared, connected with the possibility of the current-drive efficiency increasing. It was shown that for the cylindrical plasmas the local efficiency of Alfev wave current drive can be increased by one order of magnitude due to gradient forces, for the kinetic Alfven waves (KAW) and the global Alfven waves 9GAW) at some range of the phase velocity. For tokamaks, this additional nonresonant current drive does not depend on the trapped particle effects, which reduce strongly the Alfven current drive efficiency in tokamaks, as it is supposed. Now, the theory development of the Alfven wave (AW) current drive is very important in the cource of the future experiments on the TCA/BR tokamak (Brazil). In this paper, an attempt is made to clarify some general aspects of this problems for magnetic traps. For large aspects ratio tokamaks, with an elongated cross-section, some general formulas concerning the untrapped and trapped particles dynamics and their input to the Landau damping of the Alfven waves, are presented. They are supposed to be used for the further development of the Alfven current drive theory

  15. Current drive by Alfven waves in elongated cross section tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Tsypin, V.S.; Elfimov, A.G.; Nekrasov, F.M.; Azevedo, C.A. [Universidade Federal, Rio de Janeiro, RJ (Brazil). Inst. de Fisica; Assis, A.S. de [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Inst. de Fisica

    1997-12-31

    Full text. The problem of the noninductive current drive in cylindrical plasma model and in circular cross-section tokamaks had been already discussed intensively. At the beginning of the study of this problem it have been clear that there are significant difficulties in using of the current-drive in toroidal magnetic traps, especially in a tokamak reactor. Thus, in the case of the lower-hybrid current-drive the efficiency of this current-drive drops strongly as the plasma density increases. For the Alfven waves, there is an opinion that the efficiency of the current-drive drops as a result of waves absorption by the trapped particles 1,2. Okhawa proposed that the current in a magnetized plasma can be maintained also by means of forces, depending on the radiofrequency (rf) field amplitude gradients (the helicity injection). This idea was developed later, some new hopes appeared, connected with the possibility of the current-drive efficiency increasing. It was shown that for the cylindrical plasmas the local efficiency of Alfev wave current drive can be increased by one order of magnitude due to gradient forces, for the kinetic Alfven waves (KAW) and the global Alfven waves (GAW) at some range of the phase velocity. For tokamaks, this additional nonresonant current drive does not depend on the trapped particle effects, which reduce strongly the Alfven current drive efficiency in tokamaks, as it is supposed. Now, the theory development of the Alfven wave (AW) current drive is very important in the cource of the future experiments on the TCA/BR tokamak (Brazil). In this paper, an attempt is made to clarify some general aspects of this problems for magnetic traps. For large aspects ratio tokamaks, with an elongated cross-section, some general formulas concerning the untrapped and trapped particles dynamics and their input to the Landau damping of the Alfven waves, are presented. They are supposed to be used for the further development of the Alfven current drive theory

  16. Super-Planckian Thermophotovoltaics Without Vacuum Gaps

    Science.gov (United States)

    Mirmoosa, M. S.; Biehs, S.-A.; Simovski, C. R.

    2017-11-01

    We introduce the concept of a thermophotovoltaic system whose emitter is separated from the photovoltaic cell by an intermediate thick slab of gallium arsenide. Owing to the engineered structure of the emitter (a multilayer structure of negative- and positive-ɛ layers) together with a high refractiveindex and transparency of the intermediate slab, we achieve a super-Planckian and frequency-selective spectrum of radiative heat transfer which is desirable for the efficient performance of thermophotovoltaic systems.

  17. Physics at SuperLEAR: Workshop summary

    International Nuclear Information System (INIS)

    Dover, C.B.

    1990-11-01

    The major themes of the physics program to be explored at the proposed SuperLEAR facility are summarized. These include the study of charmonium spectroscopy, searches for CP violation in hyperon decays, exploration of hadron spectroscopy and gluon dynamics, particularly of non-Q bar Q systems, and bar p-nucleus annihilation as a means of probing the mechanisms of charm and strangeness production as well as the dynamics of heated nuclear matter. 40 refs., 3 tabs

  18. Super-allowed Fermi beta-decay

    International Nuclear Information System (INIS)

    Wilkinson, D.H.

    2005-01-01

    A final analysis of J π =0 + ->0 + super-allowed Fermi transitions yields vertical bar V ud vertical bar 2 =0.9500±0.0007; vertical bar V ud vertical bar 2 + vertical bar V us vertical bar 2 + vertical bar V ub vertical bar 2 =0.9999±0.0011 with the operational vector coupling constant G V */(-bar c) 3 =(1.15052±0.00021)x10 -5 GeV -2

  19. Storytelling Revealed in Super Bowl 2016 Advertisements

    OpenAIRE

    Rellahan, Celina

    2016-01-01

    This thesis investigates the use of storytelling in advertising applications and its influence on the instigation of social activity as measured by online views and social activity generated for advertisements broadcast during the 2016 Super Bowl. The thesis aims at identifying those elements of storytelling that are found in these advertisements and relating these characteristics to the success of the promotion in terms of immediate engagement of the viewing audience. The thesis present...

  20. Super-activating Quantum Memory with Entanglement

    OpenAIRE

    Guan, Ji; Feng, Yuan; Ying, Mingsheng

    2017-01-01

    Noiseless subsystems were proved to be an efficient and faithful approach to preserve fragile information against decoherence in quantum information processing and quantum computation. They were employed to design a general (hybrid) quantum memory cell model that can store both quantum and classical information. In this Letter, we find an interesting new phenomenon that the purely classical memory cell can be super-activated to preserve quantum states, whereas the null memory cell can only be...

  1. [Clinical application of super-link system theory in spinal cord injury patients during rehabilitation stage].

    Science.gov (United States)

    Chen, Hsiao-Yu

    2008-04-01

    The purpose of this paper is to introduce Super-Link System Theory, which is a theory of spinal cord injury rehabilitation. This theory has been developed using the grounded theory research method. By explaining the procedure for establishing a super-link system the paper explains the complex structure of this theory. Super-Link System Theory emphasizes that rehabilitation nurses 'build up their interpersonal relationships' with clients, family caregivers, the interdisciplinary team, and the community, and attempt to 'establish links' among them. They know these links have to be made with appropriate 'timing', and must be able to access the appropriate people when necessary. Super-link systems include the following four links: link to client with spinal cord injury, link to family caregiver, link to interdisciplinary rehabilitation team, and link to community. It can enable rehabilitation nurses to provide a better quality of nursing care to clients and their family caregivers, as well as promote their professional position in the interdisciplinary rehabilitation team.

  2. Super-Resolution Microscopy: Shedding Light on the Cellular Plasma Membrane.

    Science.gov (United States)

    Stone, Matthew B; Shelby, Sarah A; Veatch, Sarah L

    2017-06-14

    Lipids and the membranes they form are fundamental building blocks of cellular life, and their geometry and chemical properties distinguish membranes from other cellular environments. Collective processes occurring within membranes strongly impact cellular behavior and biochemistry, and understanding these processes presents unique challenges due to the often complex and myriad interactions between membrane components. Super-resolution microscopy offers a significant gain in resolution over traditional optical microscopy, enabling the localization of individual molecules even in densely labeled samples and in cellular and tissue environments. These microscopy techniques have been used to examine the organization and dynamics of plasma membrane components, providing insight into the fundamental interactions that determine membrane functions. Here, we broadly introduce the structure and organization of the mammalian plasma membrane and review recent applications of super-resolution microscopy to the study of membranes. We then highlight some inherent challenges faced when using super-resolution microscopy to study membranes, and we discuss recent technical advancements that promise further improvements to super-resolution microscopy and its application to the plasma membrane.

  3. HD 97658 and its super-Earth

    Directory of Open Access Journals (Sweden)

    Van Grootel V.

    2015-01-01

    Full Text Available Super-Earths transiting nearby bright stars are key objects that simultaneously allow for accurate measurements of both their mass and radius, providing essential constraints on their internal composition. We present the confirmation, based on Spitzer observations, that the super-Earth HD 97658 b transits its host star. HD 97658 is a low-mass (M* = 0.77 ± 0.05 M⊙ K1 dwarf, as determined from the Hipparcos parallax and stellar evolution modeling. To constrain the planet parameters, we carry out Bayesian global analyses of Keck-HIRES radial velocities, and MOST and Spitzer photometry. HD 97658 b is a massive (MP = 7.55−0.79+0.83 M⊕ and large (RP = 2.247−0.095+0.098 R⊕ at 4.5 μm super-Earth. We investigate the possible internal compositions for HD 97658 b. Our results indicate a large rocky component, by at least 60% by mass, and very little H-He components, at most 2% by mass. We also discuss how future asteroseismic observations can improve the knowledge of the HD 97658 system, in particular by constraining its age.

  4. SuperB Progress Reports - Physics

    CERN Document Server

    O'Leary, B.; Ramon, M.; Pous, E.; De Fazio, F.; Palano, A.; Eigen, G.; Asgeirsson, D.; Cheng, C.H.; Chivukula, A.; Echenard, B.; Hitlin, D.G.; Porter, F.; Rakitin, A.; Heinemeyer, S.; McElrath, B.; Andreassen, R.; Meadows, B.; Sokoloff, M.; Blanke, M.; Lesiak, T.; Shindou, T.; Ronga, F.; Baldini, W.; Bettoni, D.; Calabrese, R.; Cibinetto, G.; Luppi, E.; Rama, M.; Bossi, F.; Guido, E.; Patrignani, C.; Tosi, S.; Davies, C.; Lunghi, E.; Haisch, U.; Hurth, T.; Westhoff, S.; Crivellin, A.; Hofer, L.; Goto, T.; Brown, David Nathan; Branco, G.C.; Zupan, J.; Herrero, M.; Rodriguez-Sanchez, A.; Simi, G.; Tackmann, F.J.; Biassoni, P.; Lazzaro, A.; Lombardo, V.; Palombo, F.; Stracka, S.; Lindemann, D.M.; Robertson, S.H.; Duling, B.; Gemmler, K.; Gorbahn, M.; Jager, S.; Paradisi, P.; Straub, D.M.; Bigi, I.; Asner, D.M.; Fast, J.E.; Kouzes, R.T.; Morandin, M.; Rotondo, M.; Ben-Haim, E.; Arnaud, N.; Burmistrov, L.; Kou, E.; Perez, A.; Stocchi, A.; Viaud, B.; Domingo, F.; Piccinini, F.; Manoni, E.; Batignani, G.; Cervelli, A.; Forti, F.; Giorgi, M.; Lusiani, A.; Oberhof, B.; Paoloni, E.; Neri, N.; Walsh, J.; Bevan, A.; Bona, M.; Walker, C.; Weiland, C.; Lenz, A.; Gonzalez-Sprinberg, G.; Faccini, R.; Renga, F.; Polosa, A.; Silvestrini, L.; Virto, J.; Ciuchini, M.; Lubicz, V.; Tarantino, C.; Wilson, F.F.; Carpinelli, M.; Huber, T.; Mannel, T.; Graham, M.; Ratcliff, B.N.; Santoro, V.; Sekula, S.; Shougaev, K.; Soffer, A.; Shimizu, Y.; Gambino, P.; Mussa, R.; Nardecchia, M.; Stal, O.; Bernabeu, J.; Botella, F.; Jung, M.; Lopez March, N.; Martinez Vidal, F.; Oyanguren, A.; Pich, A.; Lozano, M.A.Sanchis; Vidal, J.; Vives, O.; Banerjee, S.; Roney, J.M.; Petrov, A.A.; Flood, K.

    2010-01-01

    SuperB is a high luminosity e+e- collider that will be able to indirectly probe new physics at energy scales far beyond the reach of any man made accelerator planned or in existence. Just as detailed understanding of the Standard Model of particle physics was developed from stringent constraints imposed by flavour changing processes between quarks, the detailed structure of any new physics is severely constrained by flavour processes. In order to elucidate this structure it is necessary to perform a number of complementary studies of a set of golden channels. With these measurements in hand, the pattern of deviations from the Standard Model behavior can be used as a test of the structure of new physics. If new physics is found at the LHC, then the many golden measurements from SuperB will help decode the subtle nature of the new physics. However if no new particles are found at the LHC, SuperB will be able to search for new physics at energy scales up to 10-100 TeV. In either scenario, flavour physics measure...

  5. Predicting the occurrence of super-storms

    Directory of Open Access Journals (Sweden)

    N. Srivastava

    2005-11-01

    Full Text Available A comparative study of five super-storms (Dst<-300 nT of the current solar cycle after the launch of SoHO, to identify solar and interplanetary variables that influence the magnitude of resulting geomagnetic storms, is described. Amongst solar variables, the initial speed of a CME is considered the most reliable predictor of the strength of the associated geomagnetic storm because fast mass ejections are responsible for building up the ram pressure at the Earth's magnetosphere. However, although most of the super-storms studied were associated with high speed CMEs, the Dst index of the resulting geomagnetic storms varied between -300 to -472 nT. The most intense storm of 20 November 2003, (Dst ~ -472 nT had its source in a comparatively smaller active region and was associated with a relatively weaker, M-class flare while all other super-storms had their origins in large active regions and were associated with strong X-class flares. However, this superstorm did not show any associated extraordinary solar and interplanetary characteristics. The study also reveals the challenge in the reliable prediction of the magnitude of a geomagnetic storm from solar and interplanetary variables.

  6. Predicting the occurrence of super-storms

    Directory of Open Access Journals (Sweden)

    N. Srivastava

    2005-11-01

    Full Text Available A comparative study of five super-storms (Dst<-300 nT of the current solar cycle after the launch of SoHO, to identify solar and interplanetary variables that influence the magnitude of resulting geomagnetic storms, is described. Amongst solar variables, the initial speed of a CME is considered the most reliable predictor of the strength of the associated geomagnetic storm because fast mass ejections are responsible for building up the ram pressure at the Earth's magnetosphere. However, although most of the super-storms studied were associated with high speed CMEs, the Dst index of the resulting geomagnetic storms varied between -300 to -472 nT. The most intense storm of 20 November 2003, (Dst ~ -472 nT had its source in a comparatively smaller active region and was associated with a relatively weaker, M-class flare while all other super-storms had their origins in large active regions and were associated with strong X-class flares. However, this superstorm did not show any associated extraordinary solar and interplanetary characteristics. The study also reveals the challenge in the reliable prediction of the magnitude of a geomagnetic storm from solar and interplanetary variables.

  7. SuperCDMS Underground Detector Fabrication Facility

    Energy Technology Data Exchange (ETDEWEB)

    Platt, M.; Mahapatra, R.; Bunker, Raymond A.; Orrell, John L.

    2018-03-01

    The SuperCDMS SNOLAB dark matter experiment processes Ge and Si crystals into fully tested phonon and ionization detectors at surface fabrication and test facilities. If not mitigated, it is anticipated that trace-level production of radioisotopes in the crystals due to exposure to cosmic rays at (or above) sea level will result in the dominant source of background events in future dark matter searches using the current SuperCDMS detector technology. Fabrication and testing of detectors in underground facilities shielded from cosmic radiation is one way to directly reduce production of trace levels of radioisotopes, thereby improving experimental sensitivity for the discovery of dark matter beyond the level of the current experiment. In this report, we investigate the cost and feasibility to establish a complete detector fabrication processing chain in an underground location to mitigate cosmogenic activation of the Ge and Si detector substrates. For a specific and concrete evaluation, we explore options for such a facility located at SNOLAB, an underground laboratory in Sudbury, Canada hosting the current and future experimental phases of SuperCDMS.

  8. SuperB Technical Design Report

    CERN Document Server

    Baszczyk, M.; Kolodziej, J.; Kucewicz, W.; Sapor, M.; Jeremie, A.; Grauges Pous, E.; Bruno, G.E.; De Robertis, G.; Diacono, D.; Donvito, G.; Fusco, P.; Gargano, F.; Giordano, F.; Loddo, F.; Loparco, F.; Maggi, G.P.; Manzari, V.; Mazziotta, M.N.; Nappi, E.; Palano, A.; Santeramo, B.; Sgura, I.; Silvestris, L.; Spinoso, V.; Eigen, G.; Zalieckas, J.; Zhuo, Z.; Jenkovszky, L.; Balbi, G.; Boldini, M.; Bonacorsi, D.; Cafaro, V.; D'Antone, I.; Dallavalle, G.M.; Di Sipio, R.; Fabbri, F.; Fabbri, L.; Gabrielli, A.; Galli, D.; Giacomelli, P.; Giordano, V.; Giorgi, F.M.; Grandi, C.; Lax, I.; Lo Meo, S.; Marconi, U.; Montanari, A.; Pellegrini, G.; Piccinini, M.; Rovelli, T.; Semprini Cesari, N.; Torromeo, G.; Tosi, N.; Travaglini, R.; Vagnoni, V.M.; Valentinetti, S.; Villa, M.; Zoccoli, A.; Caron, J. -F.; Hearty, C.; Lu, P. F. -T.; Mattison, T.S.; McKenna, J.A.; So, R. Y.; Barnyakov, M. Yu.; Blinov, V.E.; Botov, A.A.; Druzhinin, V.P.; Golubev, V.B.; Kononov, S.A.; Kravchenko, E.A.; Levichev, E.B.; Onuchin, A.P.; Serednyakov, S.I.; Shtol, D.A.; Skovpen, Y.I.; Solodov, E.P.; Cardini, A.; Carpinelli, M.; Chao, D. S. -T.; Cheng, C.H.; Doll, D.A.; Echenard, B.; Flood, K.; Hanson, J.; Hitlin, D.G.; Ongmongkolkul, P.; Porter, F.C.; Zhu, R.Y.; Randazzo, N.; De La Cruz Burelo, E.; Zheng, Y.; Campos, P.; De Silva, M.; Kathirgamaraju, A.; Meadows, B.; Pushpawela, B.; Shi, Y.; Sokoloff, M.; Lopez Castro, G.; Ciaschini, V.; Franchini, P.; Giacomini, F.; Paolini, A.; Calderon Polania, G. A.; Laczek, S.; Romanowicz, P.; Szybinski, B.; Czuchry, M.; Flis, L.; Harezlak, D.; Kocot, J.; Radecki, M.; Sterzel, M.; Szepieniec, T.; Szymocha, T.; Wójcik, P.; Andreotti, M.; Baldini, W.; Calabrese, R.; Carassiti, V.; Cibinetto, G.; Cotta Ramusino, A.; Evangelisti, F.; Gianoli, A.; Luppi, E.; Malaguti, R.; Manzali, M.; Melchiorri, M.; Munerato, M.; Padoan, C.; Santoro, V.; Tomassetti, L.; Beretta, M.M.; Biagini, M.; Boscolo, M.; Capitolo, E.; de Sangro, R.; Esposito, M.; Felici, G.; Finocchiaro, G.; Gatta, M.; Gatti, C.; Guiducci, S.; Lauciani, S.; Patteri, P.; Peruzzi, I.; Piccolo, M.; Raimondi, P.; Rama, M.; Sanelli, C.; Tomassini, S.; Fabbricatore, P.; Delepine, D.; Reyes Santos, M. A.; Chrzaszcz, M.; Grzymkowski, R.; Knap, P.; Kotula, J.; Lesiak, T.; Ludwin, J.; Michalowski, J.; Pawlik, B.; Rachwal, B.; Stodulski, M.; Wiechczynski, J.; Witek, M.; Zawiejski, L.; Zdybal, M.; Aushev, V.Y.; Ustynov, A.; Arnaud, N.; Bambade, P.; Beigbeder, C.; Bogard, F.; Borsato, M.; Breton, D.; Brossard, J.; Burmistrov, L.; Charlet, D.; Chaumat, V.; Dadoun, O.; El Berni, M.; Maalmi, J.; Puill, V.; Rimbault, C.; Stocchi, A.; Tocut, V.; Variola, A.; Wallon, S.; Wormser, G.; Grancagnolo, F.; Ben-Haim, E.; Sitt, S.; Baylac, M.; Bourrion, O.; Deconto, J. -M.; Gomez Martinez, Y.; Monseu, N.; Muraz, J. -F.; Real, J. -S.; Vescovi, C.; Cenci, R.; Jawahery, A.; Roberts, D.; Twedt, E.W.; Cheaib, R.; Lindemann, D.; Nderitu, S.; Patel, P.; Robertson, S.H.; Swersky, D.; Warburton, A.; Cuautle Flores, E.; Toledo Sanchez, G.; Biassoni, P.; Bombelli, L.; Citterio, M.; Coelli, S.; Fiorini, C.; Liberali, V.; Monti, M.; Nasri, B.; Neri, N.; Palombo, F.; Sabatini, F.; Stabile, A.; Berra, A.; Giachero, A.; Gotti, C.; Lietti, D.; Maino, M.; Pessina, G.; Prest, M.; Martin, J. -P.; Simard, M.; Starinski, N.; Taras, P.; Drutskoy, A.; Makarychev, S.; Nefediev, A.V.; Aloisio, A.; Cavaliere, S.; De Nardo, G.; Della Pietra, M.; Doria, A.; Giordano, R.; Ordine, A.; Pardi, S.; Russo, G.; Sciacca, C.; Bigi, I.I.; Jessop, C.P.; Wang, W.; Bellato, M.; Benettoni, M.; Corvo, M.; Crescente, A.; Dal Corso, F.; Dosselli, U.; Fanin, C.; Gianelle, A.; Longo, S.; Michelotto, M.; Montecassiano, F.; Morandin, M.; Pengo, R.; Posocco, M.; Rotondo, M.; Simi, G.; Stroili, R.; Gaioni, L.; Manazza, A.; Manghisoni, M.; Ratti, L.; Re, V.; Traversi, G.; Zucca, S.; Bizzaglia, S.; Bizzarri, M.; Cecchi, C.; Germani, S.; Lebeau, M.; Lubrano, P.; Manoni, E.; Papi, A.; Rossi, A.; Scolieri, G.; Batignani, G.; Bettarini, S.; Casarosa, G.; Cervelli, A.; Fella, A.; Forti, F.; Giorgi, M.; Lilli, L.; Lusiani, A.; Oberhof, B.; Paladino, A.; Pantaleo, F.; Paoloni, E.; Perez Perez, A. L.; Rizzo, G.; Walsh, J.; Fernández Téllez, A.; Beck, G.; Berman, M.; Bevan, A.; Gannaway, F.; Inguglia, G.; Martin, A.J.; Morris, J.; Bocci, V.; Capodiferro, M.; Chiodi, G.; Dafinei, I.; Drenska, N.V.; Faccini, R.; Ferroni, F.; Gargiulo, C.; Gauzzi, P.; Luci, C.; Lunadei, R.; Martellotti, G.; Pellegrino, F.; Pettinacci, V.; Pinci, D.; Recchia, L.; Ruggeri, D.; Zullo, A.; Camarri, P.; Cardarelli, R.; De Santis, C.; Di Ciaccio, A.; Di Felice, V.; Di Palma, F.; Di Simone, A.; Marcelli, L.; Messi, R.; Moricciani, D.; Sparvoli, R.; Tammaro, S.; Branchini, P.; Budano, A.; Bussino, S.; Ciuchini, M.; Nguyen, F.; Passeri, A.; Ruggieri, F.; Spiriti, E.

    2013-01-01

    In this Technical Design Report (TDR) we describe the SuperB detector that was to be installed on the SuperB e+e- high luminosity collider. The SuperB asymmetric collider, which was to be constructed on the Tor Vergata campus near the INFN Frascati National Laboratory, was designed to operate both at the Upsilon(4S) center-of-mass energy with a luminosity of 10^{36} cm^{-2}s^{-1} and at the tau/charm production threshold with a luminosity of 10^{35} cm^{-2}s^{-1}. This high luminosity, producing a data sample about a factor 100 larger than present B Factories, would allow investigation of new physics effects in rare decays, CP Violation and Lepton Flavour Violation. This document details the detector design presented in the Conceptual Design Report (CDR) in 2007. The R&D and engineering studies performed to arrive at the full detector design are described, and an updated cost estimate is presented. A combination of a more realistic cost estimates and the unavailability of funds due of the global economic ...

  9. Volatile Transport in Pluto's Super Seasons

    Science.gov (United States)

    Earle, Alissa M.; Binzel, Richard; Young, Leslie; Stern, S. Alan; Olkin, Catherine B.; Ennico, Kimberly; Moore, Jeffrey M.; Weaver, Harold A.; NASA New Horizons Composition Team, The NASA New Horizons GGI Team

    2016-10-01

    The data returned from NASA's New Horizons' reconnaissance of the Pluto system shows striking albedo variations from polar to equatorial latitudes as well as sharp boundaries for longitudinal variations. Pluto has a high obliquity (currently around 119 degrees) which varies by more than 23 degrees (between roughly 103 and 127 degrees) over a period of less than 3 million years. These obliquity properties, combined with Pluto's orbital regression in longitude of perihelion (360 degrees over 3.7 million years), create epochs of "Super Seasons" on Pluto. A "Super Season" occurs, for example, when Pluto happens to be pole-on towards the Sun at the same time as perihelion. In such a case, one pole experiences a short, intense summer (relative to its long-term average) followed by a longer than average period of winter darkness. By complement, the other pole experiences a much longer, but less intense summer and short winter season. We explore the relationship between albedo variations and volatile transport for the current epoch as well as historical epochs during which Pluto experienced these "Super Seasons". Our investigation suggests Pluto's orbit creates the potential for runaway albedo variations, particularly in the equatorial region, which would create and support stark longitudinal contrasts like the ones we see between the informally named Tombaugh and Cthulhu Regios.This work was supported by the NASA New Horizons mission.

  10. Applied force and elongation in the medial rectus in esotropic patients with and without movement restriction.

    Science.gov (United States)

    Krieger, Fernanda; Cvintal, Tadeu; Bicas, Harley

    2004-12-01

    To study the different ways of expressing the force-elongation relationship in medial rectus muscles in esotropia with and without muscular restriction. Twenty-nine passive force-elongation curves were obtained without restriction (group I, n = 13) and with restriction (group II, n = 10) by means of a manual pachymeter and a digital dynamometer. In group I, the mean age was 14 years and 7 days and the mean esotropia was 53.88(Delta) while in group II the mean age was 35 years and 5 days and the mean esotropia was 60.5(Delta). Comparisons of structural muscular parameters between groups I and II were made for length (38.69 +/- 0.75 vs. 32.48 +/- 1.84 mm, p elongation relationship, whether normalized or not, followed an exponential curve. The constant c, which represents force when the elongation is zero, remained the same in all curves. In contrast, the constant b, which represents the slope of the curve, showed a significant difference between the two groups only for the curves of force-absolute elongation and tension-absolute elongation. The results imply that the constant b is better for characterizing the difference between the behavior of the medial rectus in esotropia with and without restriction. In addition, the elongation normalization showed that the contractile component is similar between the two groups and, therefore, the classical way of analysis, which does not employ normalization, is appropriate to correlate muscle properties with clinical findings.

  11. Tree-shoot elongation patterns in a gamma-irradiated northern forest community

    International Nuclear Information System (INIS)

    Buech, R.R.; Salmonson, B.J.

    1977-01-01

    Shoot elongation in the upper crowns of seven tree species was studied in a gamma-irradiated northern forest community near Rhinelander, Wis. Observations on the pattern and duration of shoot elongation are presented for the irradiation (1972) and postirradiation (1973) growing seasons. The gymnosperm Abies balsamea was the most radiosensitive species. Significant alteration in pattern and duration was observed in 1973 at exposure rates of 4 to 25 r/20-hr day; 31 r/20-hr day was lethal. At the other extreme, 116 r/20-hr day produced no significant effects on Acer saccharum shoot elongation pattern or duration. Acer rubrum, Betula papyrifera, Populus tremuloides, Quercus rubra, and Tilia americana were intermediate in radiosensitivity. Observed responses to radiation were alteration in the elongation pattern, suppression of internodal elongation, and death. Effects of the 1972 growing-season exposure were most obvious in the subsequent growing seasons. Retardation of initial elongation was characteristic of all species. Cessation of elongation was variable, even within species (e.g., P. tremuloides). The results suggest that bud differentiation and morphology and dependency on food reserves contributed to the lag in manifestation of radiation damage. The resultant crown characteristics are described and explained

  12. Functional, electrophysiological recoveries of rats with sciatic nerve lesions following transplantation of elongated DRG cells.

    Science.gov (United States)

    Dayawansa, Samantha; Zhang, Jun; Shih, Chung-Hsuan; Tharakan, Binu; Huang, Jason H

    2016-04-01

    Functional data are essential when confirming the efficacy of elongated dorsal root ganglia (DRG) cells as a substitute for autografting. We present the quantitative functional motor, electrophysiological findings of engineered DRG recipients for the first time. Elongated DRG neurons and autografts were transplanted to bridge 1-cm sciatic nerve lesions of Sprague Dawley (SD) rats. Motor recoveries of elongated DRG recipients (n=9), autograft recipients (n=9), unrepaired rats (n=9) and intact rats (n=6) were investigated using the angle board challenge test following 16 weeks of recovery. Electrophysiology studies were conducted to assess the functional recovery at 16 weeks. In addition, elongated DRGs were subjected to histology assessments. At threshold levels (35° angle) of the angle board challenge test, the autograft recipients', DRG recipients' and unrepaired group's performances were equal to each other and were less than the intact group (pDRG recipients' performance was similar to both the intact group and the autograft nerve recipients, and was better (pDRG constructs had intact signal transmission when recorded over the lesion, while the unrepaired rats did not. It was observed that elongated DRG neurons closely resembled an autograft during histological assessments. Performances of autograft and elongated DRG construct recipients were similar. Elongated DRG neurons should be further investigated as a substitute for autografting.

  13. On the Super-Turing Computational Power of Non-Uniform Families of Neuromata

    Czech Academy of Sciences Publication Activity Database

    Wiedermann, Jiří

    2002-01-01

    Roč. 12, č. 5 (2002), s. 509-516 ISSN 1210-0552. [SOFSEM 2002 Workshop on Soft Computing. Milovy, 28.11.2002-29.11.2002] R&D Projects: GA ČR GA201/00/1489 Institutional research plan: AV0Z1030915 Keywords : neuromata * Turing machines with advice * non-uniform computational complexity * super-Turing computational power Subject RIV: BA - General Mathematics

  14. HAWCStab2 with super element foundations: A new tool for frequency analysis of offshore wind turbines

    DEFF Research Database (Denmark)

    Henriksen, Lars Christian; Hansen, Anders Melchior; Kragh, Knud Abildgaard

    2013-01-01

    HAWCStab2 is a linear frequency domain aero-elastic tool, developed by DTU Wind Energy, suitable for frequency and stability analysis of horizontal axis 3 bladed wind turbines [1]. This tool has now been extended to also handle complex offshore foundation types, such as jacket structures...... and floating structures with mooring lines, using super elements calculated by the nonlinear time domain aero-elastic code HAWC2 [2,3]....

  15. Hybrid proline-rich proteins: novel players in plant cell elongation?

    Science.gov (United States)

    Dvořáková, Lenka; Srba, Miroslav; Opatrny, Zdenek; Fischer, Lukas

    2012-01-01

    Background and Aims Hybrid proline-rich proteins (HyPRPs) represent a large family of putative cell-wall proteins characterized by the presence of a variable N-terminal domain and a conserved C-terminal domain that is related to non-specific lipid transfer proteins. The function of HyPRPs remains unclear, but their widespread occurrence and abundant expression patterns indicate that they may be involved in a basic cellular process. Methods To elucidate the cellular function of HyPRPs, we modulated the expression of three HyPRP genes in tobacco (Nicotiana tabacum) BY-2 cell lines and in potato (Solanum tuberosum) plants. Key Results In BY-2 lines, over-expression of the three HyPRP genes with different types of N-terminal domains resulted in similar phenotypic changes, namely increased cell elongation, both in suspension culture and on solid media where the over-expression resulted in enhanced calli size. The over-expressing cells showed increased plasmolysis in a hypertonic mannitol solution and accelerated rate of protoplast release, suggesting loosening of the cell walls. In contrast to BY-2 lines, no phenotypic changes were observed in potato plants over-expressing the same or analogous HyPRP genes, presumably due to more complex compensatory mechanisms in planta. Conclusions Based on the results from BY-2 lines, we propose that HyPRPs, more specifically their C-terminal domains, represent a novel group of proteins involved in cell expansion. PMID:22028464

  16. Curaxin CBL0100 Blocks HIV-1 Replication and Reactivation through Inhibition of Viral Transcriptional Elongation

    Directory of Open Access Journals (Sweden)

    Maxime J. Jean

    2017-10-01

    Full Text Available Despite combination antiretroviral therapy (cART, acquired immunodeficiency syndrome (AIDS, predominantly caused by the human immunodeficiency virus type 1 (HIV-1, remains incurable. The barrier to a cure lies in the virus' ability to establish a latent infection in HIV/AIDS patients. Unsurprisingly, efforts for a sterilizing cure have focused on the “shock and kill” strategy using latency-reversing agents (LRAs to complement cART in order to eliminate these latent reservoirs. However, this method faces numerous challenges. Recently, the “block and lock” strategy has been proposed. It aims to reinforce a deep state of latency and prevent sporadic reactivation (“blip” of HIV-1 using latency-promoting agents (LPAs for a functional cure. Our studies of curaxin 100 (CBL0100, a small-molecule targeting the facilitates chromatin transcription (FACT complex, show that it blocks both HIV-1 replication and reactivation in in vitro and ex vivo models of HIV-1. Mechanistic investigation elucidated that CBL0100 preferentially targets HIV-1 transcriptional elongation and decreases the occupancy of RNA Polymerase II (Pol II and FACT at the HIV-1 promoter region. In conclusion, CBL0100 is a newly identified inhibitor of HIV-1 transcription that can be used as an LPA in the “block and lock” cure strategy.

  17. Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation.

    Science.gov (United States)

    Meyerson, Nicholas R; Zhou, Ligang; Guo, Yusong R; Zhao, Chen; Tao, Yizhi J; Krug, Robert M; Sawyer, Sara L

    2017-11-08

    TRIM25 is an E3 ubiquitin ligase that activates RIG-I to promote the antiviral interferon response. The NS1 protein from all strains of influenza A virus binds TRIM25, although not all virus strains block the interferon response, suggesting alternative mechanisms for TRIM25 action. Here we present a nuclear role for TRIM25 in specifically restricting influenza A virus replication. TRIM25 inhibits viral RNA synthesis through a direct mechanism that is independent of its ubiquitin ligase activity and the interferon pathway. This activity can be inhibited by the viral NS1 protein. TRIM25 inhibition of viral RNA synthesis results from its binding to viral ribonucleoproteins (vRNPs), the structures containing individual viral RNA segments, the viral polymerase, and multiple viral nucleoproteins. TRIM25 binding does not inhibit initiation of capped-RNA-primed viral mRNA synthesis by the viral polymerase. Rather, the onset of RNA chain elongation is inhibited because TRIM25 prohibits the movement of RNA into the polymerase complex. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

    DEFF Research Database (Denmark)

    Villa, Elizabeth; Sengupta, Jayati; Trabuco, Leonard G.

    2009-01-01

    In translation, elongation factor Tu (EF-Tu) molecules deliver aminoacyl-tRNAs to the mRNA-programmed ribosome. The GTPase activity of EF-Tu is triggered by ribosome-induced conformational changes of the factor that play a pivotal role in the selection of the cognate aminoacyl-tRNAs. We present a 6.......7-A cryo-electron microscopy map of the aminoacyl-tRNA x EF-Tu x GDP x kirromycin-bound Escherichia coli ribosome, together with an atomic model of the complex obtained through molecular dynamics flexible fitting. The model reveals the conformational changes in the conserved GTPase switch regions...... of EF-Tu that trigger hydrolysis of GTP, along with key interactions, including those between the sarcin-ricin loop and the P loop of EF-Tu, and between the effector loop of EF-Tu and a conserved region of the 16S rRNA. Our data suggest that GTP hydrolysis on EF-Tu is controlled through a hydrophobic...

  19. An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells

    Energy Technology Data Exchange (ETDEWEB)

    Whitney, John C.; Quentin, Dennis; Sawai, Shin; LeRoux, Michele; Harding, Brittany N.; Ledvina, Hannah E.; Tran, Bao Q.; Robinson, Howard; Goo, Young Ah; Goodlett, David R.; Raunser, Stefan; Mougous, Joseph D.

    2015-10-08

    Type VI secretion (T6S) influences the composition of microbial communities by catalyzing the delivery of toxins between adjacent bacterial cells. Here, we demonstrate that a T6S integral membrane toxin from Pseudomonas aeruginosa, Tse6, acts on target cells by degrading the universally essential dinucleotides NAD+ and NADP+. Structural analyses of Tse6 show that it resembles mono-ADP-ribosyltransferase proteins, such as diphtheria toxin, with the exception of a unique loop that both excludes proteinaceous ADP-ribose acceptors and contributes to hydrolysis. We find that entry of Tse6 into target cells requires its binding to an essential housekeeping protein, translation elongation factor Tu (EF-Tu). These proteins participate in a larger assembly that additionally directs toxin export and provides chaperone activity. Visualization of this complex by electron microscopy defines the architecture of a toxin-loaded T6S apparatus and provides mechanistic insight into intercellular membrane protein delivery between bacteria.

  20. Silencing SlMED18, tomato Mediator subunit 18 gene, restricts internode elongation and leaf expansion.

    Science.gov (United States)

    Wang, Yunshu; Hu, Zongli; Zhang, Jianling; Yu, XiaoHui; Guo, Jun-E; Liang, Honglian; Liao, Changguang; Chen, Guoping

    2018-02-19

    Mediator complex, a conserved multi-protein, is necessary for controlling RNA polymerase II (Pol II) transcription in eukaryotes. Given little is known about them in tomato, a tomato Mediator subunit 18 gene was isolated and named SlMED18. To further explore the function of SlMED18, the transgenic tomato plants targeting SlMED18 by RNAi-mediated gene silencing were generated. The SlMED18-RNAi lines exhibited multiple developmental defects, including smaller size and slower growth rate of plant and significantly smaller compound leaves. The contents of endogenous bioactive GA 3 in SlMED18 silenced lines were slightly less than that in wild type. Furthermore, qRT-PCR analysis indicated that expression of gibberellins biosynthesis genes such as SlGACPS and SlGA20x2, auxin transport genes (PIN1, PIN4, LAX1 and LAX2) and several key regulators, KNOX1, KNOX2, PHAN and LANCEOLATE(LA), which involved in the leaf morphogenesis were significantly down-regulated in SlMED18-RNAi lines. These results illustrated that SlMED18 plays an essential role in regulating plant internode elongation and leaf expansion in tomato plants and it acts as a key positive regulator of gibberellins biosynthesis and signal transduction as well as auxin proper transport signalling. These findings are the basis for understanding the function of the individual Mediator subunits in tomato.

  1. Further results on super graceful labeling of graphs

    Directory of Open Access Journals (Sweden)

    Gee-Choon Lau

    2016-08-01

    Full Text Available Let G=(V(G,E(G be a simple, finite and undirected graph of order p and size q. A bijection f:V(G∪E(G→{k,k+1,k+2,…,k+p+q−1} such that f(uv=|f(u−f(v| for every edge uv∈E(G is said to be a k-super graceful labeling of G. We say G is k-super graceful if it admits a k-super graceful labeling. For k=1, the function f is called a super graceful labeling and a graph is super graceful if it admits a super graceful labeling. In this paper, we study the super gracefulness of complete graph, the disjoint union of certain star graphs, the complete tripartite graphs K(1,1,n, and certain families of trees. We also present four methods of constructing new super graceful graphs. In particular, all trees of order at most 7 are super graceful. We conjecture that all trees are super graceful.

  2. Elongational flow of polymer melts at constant strain rate, constant stress and constant force

    Science.gov (United States)

    Wagner, Manfred H.; Rolón-Garrido, Víctor H.

    2013-04-01

    Characterization of polymer melts in elongational flow is typically performed at constant elongational rate or rarely at constant tensile stress conditions. One of the disadvantages of these deformation modes is that they are hampered by the onset of "necking" instabilities according to the Considère criterion. Experiments at constant tensile force have been performed even more rarely, in spite of the fact that this deformation mode is free from necking instabilities and is of considerable industrial relevance as it is the correct analogue of steady fiber spinning. It is the objective of the present contribution to present for the first time a full experimental characterization of a long-chain branched polyethylene melt in elongational flow. Experiments were performed at constant elongation rate, constant tensile stress and constant tensile force by use of a Sentmanat Extensional Rheometer (SER) in combination with an Anton Paar MCR301 rotational rheometer. The accessible experimental window and experimental limitations are discussed. The experimental data are modelled by using the Wagner I model. Predictions of the steady-start elongational viscosity in constant strain rate and creep experiments are found to be identical, albeit only by extrapolation of the experimental data to Hencky strains of the order of 6. For constant stress experiments, a minimum in the strain rate and a corresponding maximum in the elongational viscosity is found at a Hencky strain of the order of 3, which, although larger than the steady-state value, follows roughly the general trend of the steady-state elongational viscosity. The constitutive analysis also reveals that constant tensile force experiments indicate a larger strain hardening potential than seen in constant elongation rate or constant tensile stress experiments. This may be indicative of the effect of necking under constant elongation rate or constant tensile stress conditions according to the Considère criterion.

  3. pix-1 controls early elongation in parallel with mel-11 and let-502 in Caenorhabditis elegans.

    Science.gov (United States)

    Martin, Emmanuel; Harel, Sharon; Nkengfac, Bernard; Hamiche, Karim; Neault, Mathieu; Jenna, Sarah

    2014-01-01

    Cell shape changes are crucial for metazoan development. During Caenorhabditis elegans embryogenesis, epidermal cell shape changes transform ovoid embryos into vermiform larvae. This process is divided into two phases: early and late elongation. Early elongation involves the contraction of filamentous actin bundles by phosphorylated non-muscle myosin in a subset of epidermal (hypodermal) cells. The genes controlling early elongation are associated with two parallel pathways. The first one involves the rho-1/RHOA-specific effector let-502/Rho-kinase and mel-11/myosin phosphatase regulatory subunit. The second pathway involves the CDC42/RAC-specific effector pak-1. Late elongation is driven by mechanotransduction in ventral and dorsal hypodermal cells in response to body-wall muscle contractions, and involves the CDC42/RAC-specific Guanine-nucleotide Exchange Factor (GEF) pix-1, the GTPase ced-10/RAC and pak-1. In this study, pix-1 is shown to control early elongation in parallel with let-502/mel-11, as previously shown for pak-1. We show that pix-1, pak-1 and let-502 control the rate of elongation, and the antero-posterior morphology of the embryos. In particular, pix-1 and pak-1 are shown to control head, but not tail width, while let-502 controls both head and tail width. This suggests that let-502 function is required throughout the antero-posterior axis of the embryo during early elongation, while pix-1/pak-1 function may be mostly required in the anterior part of the embryo. Supporting this hypothesis we show that low pix-1 expression level in the dorsal-posterior hypodermal cells is required to ensure high elongation rate during early elongation.

  4. Evolution and Allometry of Calcaneal Elongation in Living and Extinct Primates

    Science.gov (United States)

    Boyer, Doug M.; Seiffert, Erik R.; Gladman, Justin T.; Bloch, Jonathan I.

    2013-01-01

    Specialized acrobatic leaping has been recognized as a key adaptive trait tied to the origin and subsequent radiation of euprimates based on its observed frequency in extant primates and inferred frequency in extinct early euprimates. Hypothesized skeletal correlates include elongated tarsal elements, which would be expected to aid leaping by allowing for increased rates and durations of propulsive acceleration at takeoff. Alternatively, authors of a recent study argued that pronounced distal calcaneal elongation of euprimates (compared to other mammalian taxa) was related primarily to specialized pedal grasping. Testing for correlations between calcaneal elongation and leaping versus grasping is complicated by body size differences and associated allometric affects. We re-assess allometric constraints on, and the functional significance of, calcaneal elongation using phylogenetic comparative methods, and present an evolutionary hypothesis for the evolution of calcaneal elongation in primates using a Bayesian approach to ancestral state reconstruction (ASR). Results show that among all primates, logged ratios of distal calcaneal length to total calcaneal length are inversely correlated with logged body mass proxies derived from the area of the calcaneal facet for the cuboid. Results from phylogenetic ANOVA on residuals from this allometric line suggest that deviations are explained by degree of leaping specialization in prosimians, but not anthropoids. Results from ASR suggest that non-allometric increases in calcaneal elongation began in the primate stem lineage and continued independently in haplorhines and strepsirrhines. Anthropoid and lorisid lineages show stasis and decreasing elongation, respectively. Initial increases in calcaneal elongation in primate evolution may be related to either development of hallucal-grasping or a combination of grasping and more specialized leaping behaviors. As has been previously suggested, subsequent increases in calcaneal

  5. Effect of χ Phase Formation on the Mechanical Properties of 25Cr-7Ni-4Mo-0.2N Super Duplex Stainless Steel

    International Nuclear Information System (INIS)

    Kang, Chang Yong; Kim, Jae Hwan

    2011-01-01

    This study was carried out to investigate the precipitation behavior of χ phase and effect of χ-phase which precipitated at the initial stage of aging on mechanical properties of 25%Cr-7%Ni-4%Mo-0.2%N super duplex stainless steel. χ-phase was precipitated mainly at the interface of ferrite / austenite phases and inside of the ferrite phase at the initial stage of aging, and it was transformed into σ-phase with an increase of aging time. The ferrite phase was decomposed into new austenite(γ 2 )phase and σ-phase by aging treatment. The hardness and tensile strength of the initial stage of aging when χ-phase was precipitated did not changed considerably, while elongation rapidly decreased. Accordingly, it is considered that χ-phase didn't affect the hardness and strength significantly, but it affected the elongation.

  6. Elongational viscosity of narrow molar mass distribution polystyrene. A Bach, K. Almdal, H.K. Rasmussen and O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Almdal, Kristoffer

    2003-01-01

    Transient and steady elongational viscosity has been measured for two narrow molar mass distributin polystyrene melts ......Transient and steady elongational viscosity has been measured for two narrow molar mass distributin polystyrene melts ...

  7. Complex matrix model duality

    International Nuclear Information System (INIS)

    Brown, T.W.

    2010-11-01

    The same complex matrix model calculates both tachyon scattering for the c=1 non-critical string at the self-dual radius and certain correlation functions of half-BPS operators in N=4 super- Yang-Mills. It is dual to another complex matrix model where the couplings of the first model are encoded in the Kontsevich-like variables of the second. The duality between the theories is mirrored by the duality of their Feynman diagrams. Analogously to the Hermitian Kontsevich- Penner model, the correlation functions of the second model can be written as sums over discrete points in subspaces of the moduli space of punctured Riemann surfaces. (orig.)

  8. Complex matrix model duality

    Energy Technology Data Exchange (ETDEWEB)

    Brown, T.W.

    2010-11-15

    The same complex matrix model calculates both tachyon scattering for the c=1 non-critical string at the self-dual radius and certain correlation functions of half-BPS operators in N=4 super- Yang-Mills. It is dual to another complex matrix model where the couplings of the first model are encoded in the Kontsevich-like variables of the second. The duality between the theories is mirrored by the duality of their Feynman diagrams. Analogously to the Hermitian Kontsevich- Penner model, the correlation functions of the second model can be written as sums over discrete points in subspaces of the moduli space of punctured Riemann surfaces. (orig.)

  9. Transient plasma injections in the dayside magnetosphere: one-to-one correlated observations by Cluster and SuperDARN

    Directory of Open Access Journals (Sweden)

    A. Marchaudon

    2004-01-01

    Full Text Available Conjunctions in the cusp between the four Cluster spacecraft and SuperDARN ground-based radars offer unique opportunities to compare the signatures of transient plasma injections simultaneously in the high-altitude dayside magnetosphere and in the ionosphere. We report here on such observations on 17 March 2001, when the IMF initially northward and duskward, turns southward and dawnward for a short period. The changes in the convection direction at Cluster are well correlated with the interplanetary magnetic field (IMF By variations. Moreover, the changes in the ionosphere follow those in the magnetosphere, with a 2–3min delay. When mapped into the ionosphere, the convection velocity at Cluster is about 1.5 times larger than measured by SuperDARN. In the high-altitude cusp, field and particle observations by Cluster display the characteristic signatures of plasma injections into the magnetosphere suggestive of Flux Transfer Events (FTEs. Simultaneous impulsive and localized convection plasma flows are observed in the ionospheric cusp by the HF radars. A clear one-to-one correlation is observed for three successive injections, with a 2–3min delay between the magnetospheric and ionospheric observations. For each event, the drift velocity of reconnected flux tubes (phase velocity has been compared in the magnetosphere and in the ionosphere. The drift velocity measured at Cluster is of the order of 400–600ms–1 when mapped into the ionosphere, in qualitative agreement with SuperDARN observations. Finally, the reconnected flux tubes are elongated in the north-south direction, with an east-west dimension of 30–60km in the ionosphere from mapped Cluster observations, which is consistent with SuperDARN observations, although slightly smaller. Key words. Ionosphere (plasma convection – Magnetospheric physics (magnetopause, cusp, and boundary layers; magnetosphere-ionosphere interactions

  10. Two modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cycle.

    Directory of Open Access Journals (Sweden)

    Tatsuro Naganuma

    Full Text Available Fatty acids (FAs are diverse molecules, and such diversity is important for lipids to exert their functions under several environmental conditions. FA elongation occurs at the endoplasmic reticulum and produces a variety of FA species; the FA elongation cycle consists of four distinct enzyme reactions. For this cycle to be driven efficiently, there must exist coordinated regulation of protein components of the FA elongation machinery. However, such regulation is poorly understood. In the present study, we performed biochemical analyses using the FA elongase ELOVL6 and the 3-ketoacyl-CoA reductase KAR, which catalyze the first and second steps of the FA elongation cycle, respectively. In vitro FA elongation assays using membrane fractions demonstrated that ELOVL6 activity was enhanced ∼10-fold in the presence of NADPH, although ELOVL6 itself did not require NADPH for its catalysis. On the other hand, KAR does use NADPH as a reductant in its enzyme reaction. Activity of purified ELOVL6 was enhanced by ∼3-fold in the presence of KAR. This effect was KAR enzyme activity-independent, since it was observed in the absence of NADPH and in the KAR mutant. However, ELOVL6 enzyme activity was further enhanced in a KAR enzyme activity-dependent manner. Therefore, KAR regulates ELOVL6 via two modes. In the first mode, KAR may induce conformational changes in ELOVL6 to become structure that can undergo catalysis. In the second mode, conversion of 3-ketoacyl-CoA to 3-hydroxyacyl-CoA by KAR may facilitate release of the product from the presumed ELOVL6-KAR complex.

  11. FPGA-based quench detection system for super-FRS super-ferric dipole prototype

    International Nuclear Information System (INIS)

    Yang Tongjun; Wu Wei; Yao Qinggao; Yuan Ping; He Yuan; Han Shaofei; Ma Lizhen

    2011-01-01

    The quench detection system for Super-FRS super-ferric dipole prototype magnet of FAIR has been designed and built. The balance bridge was used to detect quench signal. In order to avoid blind zone of quench detection, two independent bridges were used. NI PXI-7830R FPGA was used to implement filter to quench signal and algorithm of quench decision and to produce quench trigger signal. Pre-sample technique was used in quench data acquisition. The data before and after quench could be recorded for analysis later. The test result indicated that the quench of the dipole's superconducting coil could be reliably detected by the quench detection module. (authors)

  12. Bacillus anthracis Prolyl 4-Hydroxylase Interacts with and Modifies Elongation Factor Tu

    Energy Technology Data Exchange (ETDEWEB)

    Schnicker, Nicholas J. [Department; Razzaghi, Mortezaali [Department; Guha Thakurta, Sanjukta [Department; Chakravarthy, Srinivas [Biophysics; Dey, Mishtu [Department

    2017-10-17

    Prolyl hydroxylation is a very common post-translational modification and plays many roles in eukaryotes such as collagen stabilization, hypoxia sensing, and controlling protein transcription and translation. There is a growing body of evidence that suggests that prokaryotes contain prolyl 4-hydroxylases (P4Hs) homologous to the hypoxia-inducible factor (HIF) prolyl hydroxylase domain (PHD) enzymes that act on elongation factor Tu (EFTu) and are likely involved in the regulation of bacterial translation. Recent biochemical and structural studies with a PHD from Pseudomonas putida (PPHD) determined that it forms a complex with EFTu and hydroxylates a prolyl residue of EFTu. Moreover, while animal, plant, and viral P4Hs act on peptidyl proline, most prokaryotic P4Hs have been known to target free l-proline; the exceptions include PPHD and a P4H from Bacillus anthracis (BaP4H) that modifies collagen-like proline-rich peptides. Here we use biophysical and mass spectrometric methods to demonstrate that BaP4H recognizes full-length BaEFTu and a BaEFTu 9-mer peptide for site-specific proline hydroxylation. Using size-exclusion chromatography coupled small-angle X-ray scattering (SEC–SAXS) and binding studies, we determined that BaP4H forms a 1:1 heterodimeric complex with BaEFTu. The SEC–SAXS studies reveal dissociation of BaP4H dimeric subunits upon interaction with BaEFTu. While BaP4H is unusual within bacteria in that it is structurally and functionally similar to the animal PHDs and collagen P4Hs, respectively, this work provides further evidence of its promiscuous substrate recognition. It is possible that the enzyme might have evolved to hydroxylate a universally conserved protein in prokaryotes, similar to the PHDs, and implies a functional role in B. anthracis.

  13. The SuperB Project: Status and the Physics Reach

    International Nuclear Information System (INIS)

    Neri, Nicola

    2012-01-01

    The SuperB experiment is a next generation Super Flavour Factory expected to accumulate 75 ab −1 of data at the Υ(4S) in five years of nominal running, and will be built at the recently established Cabibbo Laboratory on the outskirts of Rome. In addition to running data at the Υ(4S), SuperB will be able to accumulate data from the ψ(3770) up to the Υ(6S). A polarized electron beam enables unique physics opportunities at SuperB. The large samples of B, D and τ decays that will be recorded at SuperB can be used to provide both stringent constraints on new physics scenarios, and over-constraints on the Standard Model. We present the status of the project as well as the physics potential of SuperB.

  14. Super capacitor modeling with artificial neural network (ANN)

    Energy Technology Data Exchange (ETDEWEB)

    Marie-Francoise, J.N.; Gualous, H.; Berthon, A. [Universite de Franche-Comte, Lab. en Electronique, Electrotechnique et Systemes (L2ES), UTBM, INRETS (LRE T31) 90 - Belfort (France)

    2004-07-01

    This paper presents super-capacitors modeling using Artificial Neural Network (ANN). The principle consists on a black box nonlinear multiple inputs single output (MISO) model. The system inputs are temperature and current, the output is the super-capacitor voltage. The learning and the validation of the ANN model from experimental charge and discharge of super-capacitor establish the relationship between inputs and output. The learning and the validation of the ANN model use experimental results of 2700 F, 3700 F and a super-capacitor pack. Once the network is trained, the ANN model can predict the super-capacitor behaviour with temperature variations. The update parameters of the ANN model are performed thanks to Levenberg-Marquardt method in order to minimize the error between the output of the system and the predicted output. The obtained results with the ANN model of super-capacitor and experimental ones are in good agreement. (authors)

  15. Experimental investigation of a super performance dew point air cooler

    International Nuclear Information System (INIS)

    Xu, Peng; Ma, Xiaoli; Zhao, Xudong; Fancey, Kevin

    2017-01-01

    Highlights: •The cooler had a complex heat & mass exchanger with an advanced wet material layer. •Intermittent water supply scheme was implemented. •The cooler achieved 100–160% higher COP compared to the existing dew point coolers. •Electricity use of the cooler was reduced by 50–70% compared to existing dew coolers. •This optimal working air ratio was 0.364 that enabled maximised cooling effectiveness. -- Abstract: This paper presents an experimental investigation of a super performance dew point air cooler which, by employing a super performance wet material layer, innovative heat and mass exchanger and intermittent water supply scheme, has achieved a significantly higher energy efficiency (i.e. Coefficient of Performance, COP) and a much lower electrical energy use compared to the existing air coolers of the same type. This involves the dedicated system design & construction, fully planned experimental testing under various simulated climatic conditions representing the climate of hot & dry, warm & dry, moderate, warm & humid and standard lab testing condition, testing results analysis and discussion, as well as the parallel comparison against the commercial dew point air cooler. Under the standard test condition, i.e. dry bulb temperature of 37.8 °C and coincident wet bulb temperature of 21.1 °C, the prototype cooler achieved the wet-bulb cooling effectiveness of 114% and dew-point cooling effectiveness of 75%, yielding a significantly high COP value of 52.5 at the optimal working air ratio of 0.364. The testing also indicated that the lower inlet air relative humidity led to a higher cooling efficiency, while the lower cooling output helped increase COP and cooling effectiveness (including the wet-bulb effectiveness and dew-point effectiveness) of the cooler.

  16. Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae.

    Directory of Open Access Journals (Sweden)

    Tomas Grousl

    Full Text Available In response to severe environmental stresses eukaryotic cells shut down translation and accumulate components of the translational machinery in stress granules (SGs. Since they contain mainly mRNA, translation initiation factors and 40S ribosomal subunits, they have been referred to as dominant accumulations of stalled translation preinitiation complexes. Here we present evidence that the robust heat shock-induced SGs of S. cerevisiae also contain translation elongation factors eEF3 (Yef3p and eEF1Bγ2 (Tef4p as well as translation termination factors eRF1 (Sup45p and eRF3 (Sup35p. Despite the presence of the yeast prion protein Sup35 in heat shock-induced SGs, we found out that its prion-like domain is not involved in the SGs assembly. Factors eEF3, eEF1Bγ2 and eRF1 were accumulated and co-localized with Dcp2 foci even upon a milder heat shock at 42°C independently of P-bodies scaffolding proteins. We also show that eEF3 accumulations at 42°C determine sites of the genuine SGs assembly at 46°C. We suggest that identification of translation elongation and termination factors in SGs might help to understand the mechanism of the eIF2α factor phosphorylation-independent repression of translation and SGs assembly.

  17. Overexpression of rice LRK1 restricts internode elongation by down-regulating OsKO2.

    Science.gov (United States)

    Yang, Mengfei; Qi, Weiwei; Sun, Fan; Zha, Xiaojun; Chen, Mingluan; Huang, Yunqing; Feng, Yu-Qi; Yang, Jinshui; Luo, Xiaojin

    2013-01-01

    Rice (Oryza sativa) has the potential to undergo rapid internodal elongation which determines plant height. Gibberellin is involved in internode elongation. Leucine-rich repeat receptor-like kinases (LRR-RLKs) are the largest subfamily of transmembrane receptor-like kinases in plants. LRR-RLKs play important functions in mediating a variety of cellular processes and regulating responses to environmental signals. LRK1, a PSK receptor homolog, is a member of the LRR-RLK family. In the present study, differences in ectopic expression of LRK1 were consistent with extent of rice internode elongation. Analyses of gene expression demonstrated that LRK1 restricts gibberellin biosynthesis during the internode elongation process by down-regulation of the gibberellin biosynthetic gene coding for ent-kaurene oxidase.

  18. Suppression of vertical instability in elongated current-carrying plasmas by applying stellarator rotational transform

    International Nuclear Information System (INIS)

    ArchMiller, M. C.; Cianciosa, M. R.; Ennis, D. A.; Hanson, J. D.; Hartwell, G. J.; Hebert, J. D.; Herfindal, J. L.; Knowlton, S. F.; Ma, X.; Maurer, D. A.; Pandya, M. D.; Traverso, P.

    2014-01-01

    The passive stability of vertically elongated current-carrying toroidal plasmas has been investigated in the Compact Toroidal Hybrid, a stellarator/tokamak hybrid device. In this experiment, the fractional transform f, defined as the ratio of the imposed external rotational transform from stellarator coils to the total rotational transform, was varied from 0.04 to 0.50, and the elongation κ was varied from 1.4 to 2.2. Plasmas that were vertically unstable were evidenced by motion of the plasma in the vertical direction. Vertical drifts are measured with a set of poloidal field pickup coils. A three chord horizontally viewing interferometer and a soft X-ray diode array confirmed the drifts. Plasmas with low fractional transform and high elongation are the most susceptible to vertical instability, consistent with analytic predictions that the vertical mode in elongated plasmas can be stabilized by the poloidal field of a relatively weak stellarator equilibrium

  19. A case of abdominal compartment syndrome derived from simple elongated sigmoid colon in an elderly man

    Directory of Open Access Journals (Sweden)

    Masaaki Shida

    2016-01-01

    Discussion and conclusion: Considering the increase in the aging population, we must bear in mind that abdominal compartment syndrome may occur in simple elongated sigmoid colon without other risk factors.

  20. Uni-axial Elongational Viscosity of Linear and Branched polymer melts

    DEFF Research Database (Denmark)

    Hassager, Ole; Nielsen, Jens Kromann; Rasmussen, Henrik Koblitz

    2005-01-01

    About 40 years ago interest in the measurement of elongational viscosity of polymer melts started to grow. Here we present measurements of transient (and steady) uni-axial elongational viscosity, using the FSR, of the following melts: Four narrow MMD polystyrene (PS) samples with weight......-average molar mass Mw in the range of 50k to 390k. Three different bi-disperse samples, mixed from the narrow MMD PS. Two low-density polyethylene (LDPE) melts (Lupolen 1840D and 3020D). A steady-state viscosity was kept for 1-2.5 Hencky strain units in all measurements.The measurements on the bi-disperse PS...... melts have demonstrated that both the transient and steady elongational viscosity is quite sensitive to polydispersity. Bi-disperse PS resembles the behaviour of mono-disperse melts only at elongational rates larger then the inverse of maximal time constant of the smallest molecule. As observed in Boger...

  1. Characterization of pollutant dispersion near elongated buildings based on wind tunnel simulations-BDW-1

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data set is associated with the results found in the journal article: Perry et al, 2016. Characterization of pollutant dispersion near elongated buildings based...

  2. Mutation of the conserved Gly83 and Gly94 in Escherichia coli elongation factor Tu. Indication of structural pivots

    DEFF Research Database (Denmark)

    Kjaersgård, I V; Knudsen, Charlotte Rohde; Wiborg, O

    1995-01-01

    Elongation factor Tu from Escherichia coli cycles between an active conformation where GTP is bound, and an inactive conformation where GDP is bound. Between the two conformations, elongation factor Tu undergoes major structural changes. The aim of this work has been to reveal the role of two ver...... is an important pivot point in elongation factor-Tu. Udgivelsesdato: 1995-Feb-15...

  3. Verification of SuperMC with ITER C-Lite neutronic model

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Shu [School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, 230027 (China); Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); Yu, Shengpeng [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); He, Peng, E-mail: peng.he@fds.org.cn [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China)

    2016-12-15

    Highlights: • Verification of the SuperMC Monte Carlo transport code with ITER C-Lite model. • The modeling of the ITER C-Lite model using the latest SuperMC/MCAM. • All the calculated quantities are consistent with MCNP well. • Efficient variance reduction methods are adopted to accelerate the calculation. - Abstract: In pursit of accurate and high fidelity simulation, the reference model of ITER is becoming more and more detailed and complicated. Due to the complexity in geometry and the thick shielding of the reference model, the accurate modeling and precise simulaion of fusion neutronics are very challenging. Facing these difficulties, SuperMC, the Monte Carlo simulation software system developed by the FDS Team, has optimized its CAD interface for the automatic converting of more complicated models and increased its calculation efficiency with advanced variance reduction methods To demonstrate its capabilites of automatic modeling, neutron/photon coupled simulation and visual analysis for the ITER facility, numerical benchmarks using the ITER C-Lite neutronic model were performed. The nuclear heating in divertor and inboard toroidal field (TF) coils and a global neutron flux map were evaluated. All the calculated nuclear heating is compared with the results of the MCNP code and good consistencies between the two codes is shown. Using the global variance reduction methods in SuperMC, the average speed-up is 292 times for the calculation of inboard TF coils nuclear heating, and 91 times for the calculation of global flux map, compared with the analog run. These tests have shown that SuperMC is suitable for the design and analysis of ITER facility.

  4. Movement of endogenous calcium in the elongating zone of graviresponding roots of Zea mays

    Science.gov (United States)

    Moore, R.; Cameron, I. L.; Smith, N. K.

    1989-01-01

    Endogenous calcium (Ca) accumulates along the lower side of the elongating zone of horizontally oriented roots of Zea mays cv. Yellow Dent. This accumulation of Ca correlates positively with the onset of gravicurvature, and occurs in the cytoplasm, cell walls and mucilage of epidermal cells. Corresponding changes in endogenous Ca do not occur in cortical cells of the elongating zone of intact roots. These results indicate that the calcium asymmetries associated with root gravicurvature occur in the outermost layers of the root.

  5. Are lesions induced by ionizing radiation direct blocks to DNA chain elongation

    International Nuclear Information System (INIS)

    Painter, R.B.

    1983-01-01

    Ionizing radiation blocks DNA chain elongation in normal diploid fibroblasts but not in fibroblasts from patients with ataxia-telangiectasia, even though there are no differences in the damage induced between the two cell types. This difference suggests that radiation-induced lesions in DNA are not themselves blocks to chain elongation in ataxia cells and raises the possibility that in normal cells a mediator exists between DNA damage and chain termination

  6. On nature of spontaneous elongation of polymers preliminarily stretched in adsorption-active media under irradiation

    International Nuclear Information System (INIS)

    Sinevich, E.A.; Prazdnichnyj, A.M.; Tikhomirov, V.S.; Bakeev, N.F.

    1989-01-01

    The nature of the spontaneous elongation under irradiation with fast electrons of polymers preliminary stretched in adsorption-active media has been studied. This effect is related with radiation-induced heating of microporous polymer samples. Its manifestation in amorphous PETP requires the presence of crazes having well developed microfibrillar structure. The spontaneous elongation effect is shown to be a result of crystallization of partially oriented material in transitional regions relating the oriented material of microfibrils inside crazes with nonstrained polymer between them

  7. Transcription elongation. Heterogeneous tracking of RNA polymerase and its biological implications.

    Science.gov (United States)

    Imashimizu, Masahiko; Shimamoto, Nobuo; Oshima, Taku; Kashlev, Mikhail

    2014-01-01

    Regulation of transcription elongation via pausing of RNA polymerase has multiple physiological roles. The pausing mechanism depends on the sequence heterogeneity of the DNA being transcribed, as well as on certain interactions of polymerase with specific DNA sequences. In order to describe the mechanism of regulation, we introduce the concept of heterogeneity into the previously proposed alternative models of elongation, power stroke and Brownian ratchet. We also discuss molecular origins and physiological significances of the heterogeneity.

  8. N=2 super - W3(2) algebra in superfields

    International Nuclear Information System (INIS)

    Krivonos, S.; Sorin, A.

    1995-05-01

    It is presented a manifestly N=2 supersymmetric formulation of N=2 super-W 3 (2) algebra (its classical version) in terms of the spin 1 unconstrained generating a N=2 superconformal subalgebra and the spins 1/2, 2 fermionic constrained supercurrents. It is considered a superfield reduction of N=2 super-W 3 (2) to N=2 super-W 3 and construct a family of evolution equations for which N=2 super-W 3 (2) provides the second Hamiltonian structure

  9. 1,8-cineole inhibits both proliferation and elongation of BY-2 cultured tobacco cells.

    Science.gov (United States)

    Yoshimura, Hiroko; Sawai, Yu; Tamotsu, Satoshi; Sakai, Atsushi

    2011-03-01

    Volatile monoterpenes such as 1,8-cineole inhibit the growth of Brassica campestris seedlings in a dose-dependent manner, and the growth-inhibitory effects are more severe for roots than hypocotyls. The preferential inhibition of root growth may be explained if the compounds inhibit cell proliferation more severely than cell elongation because root growth requires both elongation and proliferation of the constituent cells, whereas hypocotyl growth depends exclusively on elongation of existing cells. In order to examine this possibility, BY-2 suspension-cultured tobacco (Nicotiana tabacum) cells were treated with 1,8-cineole, and the inhibitory effects on cell proliferation and on cell elongation were assessed quantitatively. Treatment with 1,8-cineole lowered both the mitotic index and elongation of the cells in a dose-dependent manner, and the half-maximal inhibitory concentration (IC₅₀) for cell elongation was lower than that for cell proliferation. Moreover, 1,8-cineole also inhibited starch synthesis, with IC₅₀ lower than that for cell proliferation. Thus, the inhibitory effects of 1,8-cineole were not specific to cell proliferation; rather, 1,8-cineole seemed inhibitory to a variety of physiological activities when it was in direct contact with target cells. Based on these results, possible mechanisms for the mode of action of 1,8-cineole and for its preferential inhibition on root growth are discussed.

  10. Gravimorphism in rice and barley: promotion of leaf elongation by vertical inversion in agravitropically growing plants.

    Science.gov (United States)

    Abe, K; Takahashi, H; Suge, H

    1998-12-01

    We have compared shoot responses of agravitropic rice and barley plants to vertical inversion with those of normal ones. When rice plants were vertically inverted, the main stems of a japonica type of rice, cv. Kamenoo, showed negative gravitropism at nodes 2-15 of both elongated and non-elongated internodes. However, shoots of lazy line of rice, lazy-Kamenoo, bent gravitropically at nodes 11-15 only elongated internodes but not at nodes 2-10 of non-elongated ones. Thus, shoots of Kamenoo responded gravitropically at all stages of growth, whereas shoots of lazy-Kamenoo did not show gravitropic response before heading. In Kamenoo plants, lengths of both leaf-sheath and leaf-blade were shortened by vertical inversion, but those of the vertically inverted plants of lazy-Kamenoo were significantly longer than the plants in an upright position. When agravitropic and normal plants of barley were vertically inverted, the same results as in rice were obtained; elongation of both leaf-sheath and leaf-blade was inhibited in normal barley plants, Chikurin-Ibaragi No. 1, but significantly stimulated in agravitropic plants of serpentina barley. These results suggest that vertical inversion of rice and barley plants enhances the elongation growth of leaves in the absence of tropistic response.

  11. Contribution of Cell Elongation to the Biofilm Formation of Pseudomonas aeruginosa during Anaerobic Respiration

    Science.gov (United States)

    Park, Yongjin; Yoon, Sang Sun

    2011-01-01

    Pseudomonas aeruginosa, a gram-negative bacterium of clinical importance, forms more robust biofilm during anaerobic respiration, a mode of growth presumed to occur in abnormally thickened mucus layer lining the cystic fibrosis (CF) patient airway. However, molecular basis behind this anaerobiosis-triggered robust biofilm formation is not clearly defined yet. Here, we identified a morphological change naturally accompanied by anaerobic respiration in P. aeruginosa and investigated its effect on the biofilm formation in vitro. A standard laboratory strain, PAO1 was highly elongated during anaerobic respiration compared with bacteria grown aerobically. Microscopic analysis demonstrated that cell elongation likely occurred as a consequence of defective cell division. Cell elongation was dependent on the presence of nitrite reductase (NIR) that reduces nitrite (NO2 −) to nitric oxide (NO) and was repressed in PAO1 in the presence of carboxy-PTIO, a NO antagonist, demonstrating that cell elongation involves a process to respond to NO, a spontaneous byproduct of the anaerobic respiration. Importantly, the non-elongated NIR-deficient mutant failed to form biofilm, while a mutant of nitrate reductase (NAR) and wild type PAO1, both of which were highly elongated, formed robust biofilm. Taken together, our data reveal a role of previously undescribed cell biological event in P. aeruginosa biofilm formation and suggest NIR as a key player involved in such process. PMID:21267455

  12. An Equatorial Contractile Mechanism Drives Cell Elongation but not Cell Division

    Science.gov (United States)

    Denker, Elsa; Bhattachan, Punit; Deng, Wei; Mathiesen, Birthe T.; Jiang, Di

    2014-01-01

    Cell shape changes and proliferation are two fundamental strategies for morphogenesis in animal development. During embryogenesis of the simple chordate Ciona intestinalis, elongation of individual notochord cells constitutes a crucial stage of notochord growth, which contributes to the establishment of the larval body plan. The mechanism of cell elongation is elusive. Here we show that although notochord cells do not divide, they use a cytokinesis-like actomyosin mechanism to drive cell elongation. The actomyosin network forming at the equator of each notochord cell includes phosphorylated myosin regulatory light chain, α-actinin, cofilin, tropomyosin, and talin. We demonstrate that cofilin and α-actinin are two crucial components for cell elongation. Cortical flow contributes to the assembly of the actomyosin ring. Similar to cytokinetic cells, membrane blebs that cause local contractions form at the basal cortex next to the equator and participate in force generation. We present a model in which the cooperation of equatorial actomyosin ring-based constriction and bleb-associated contractions at the basal cortex promotes cell elongation. Our results demonstrate that a cytokinesis-like contractile mechanism is co-opted in a completely different developmental scenario to achieve cell shape change instead of cell division. We discuss the occurrences of actomyosin rings aside from cell division, suggesting that circumferential contraction is an evolutionally conserved mechanism to drive cell or tissue elongation. PMID:24503569

  13. Super-Hamiltonian Structures and Conservation Laws of a New Six-Component Super-Ablowitz-Kaup-Newell-Segur Hierarchy

    Directory of Open Access Journals (Sweden)

    Fucai You

    2014-01-01

    Full Text Available A six-component super-Ablowitz-Kaup-Newell-Segur (-AKNS hierarchy is proposed by the zero curvature equation associated with Lie superalgebras. Supertrace identity is used to furnish the super-Hamiltonian structures for the resulting nonlinear superintegrable hierarchy. Furthermore, we derive the infinite conservation laws of the first two nonlinear super-AKNS equations in the hierarchy by utilizing spectral parameter expansions. PACS: 02.30.Ik; 02.30.Jr; 02.20.Sv.

  14. Calibration of Super-Kamiokande using an electron LINAC The Super-Kamiokande Collaboration

    CERN Document Server

    Nakahata, M; Hayakawa, T

    1999-01-01

    In order to calibrate the Super-Kamiokande experiment for solar neutrino measurements, a linear accelerator (LINAC) for electrons was installed at the detector. LINAC data were taken at various positions in the detector volume, tracking the detector response in the variables relevant to solar neutrino analysis. In particular, the absolute energy scale is now known with less than 1% uncertainty.

  15. Super-Liouville — double Liouville correspondence

    Science.gov (United States)

    Hadasz, Leszek; Jaskólski, Zbigniew

    2014-05-01

    The AGT motivated relation between the tensor product of the = 1 super-Liouville field theory with the imaginary free fermion (SL) and a certain projected tensor product of the real and the imaginary Liouville field theories (LL) is analyzed. Using conformal field theory techniques we give a complete proof of the equivalence in the NS sector. It is shown that the SL-LL correspondence is based on the equivalence of chiral objects including suitably chosen chiral structure constants of all the three Liouville theories involved.

  16. Super-Liouville — double Liouville correspondence

    International Nuclear Information System (INIS)

    Hadasz, Leszek; Jaskólski, Zbigniew

    2014-01-01

    The AGT motivated relation between the tensor product of the N=1 super-Liouville field theory with the imaginary free fermion (SL) and a certain projected tensor product of the real and the imaginary Liouville field theories (LL) is analyzed. Using conformal field theory techniques we give a complete proof of the equivalence in the NS sector. It is shown that the SL-LL correspondence is based on the equivalence of chiral objects including suitably chosen chiral structure constants of all the three Liouville theories involved.

  17. Super-Liouville — double Liouville correspondence

    Energy Technology Data Exchange (ETDEWEB)

    Hadasz, Leszek [M. Smoluchowski Institute of Physics, Jagiellonian University,W. Reymonta 4, 30-059 Kraków (Poland); Jaskólski, Zbigniew [Institute of Theoretical Physics, University of Wrocław,pl. M. Borna 1, 95-204 Wrocław (Poland)

    2014-05-27

    The AGT motivated relation between the tensor product of the N=1 super-Liouville field theory with the imaginary free fermion (SL) and a certain projected tensor product of the real and the imaginary Liouville field theories (LL) is analyzed. Using conformal field theory techniques we give a complete proof of the equivalence in the NS sector. It is shown that the SL-LL correspondence is based on the equivalence of chiral objects including suitably chosen chiral structure constants of all the three Liouville theories involved.

  18. The status of the SuperHILAC

    International Nuclear Information System (INIS)

    Grunder, H.A.; Selph, F.B.

    1976-01-01

    The SuperHILAC is an Alvarez linear accelerator designed to accelerate all ions to a maximum energy of 8.5 MeV/u. Duplication of effort is made possible by the utilization of a technique known as timeshare - two different ion beams are accelerated independently through the same linac structure. Recent operating experience is reviewed. Also discussed are recent major improvements which have been made to the accelerator, and a proposed improvement which will increase reliability and beam intensity for the very heavy ions (A > approximately 84) by adding a third injector of improved design

  19. Containment Safety Of Super Phenix : Essai Mars

    Science.gov (United States)

    Falgayrettes, M. F.; Fiche, C.; Hamon, P.

    1985-02-01

    The protection of people and property must be assured by every situation around an industrial power plant. That is why the FRENCH Commissariat a l'Energie Atomique has defined the size of the confinement of Super Phenix to withstand the worst highly hypothetical accident. The study of the strength of the confinement has been carried out by two complementary means : - Calculation (Display poster # 491 188), - Experiment : reactor mock-up. The latter is presented in the film. The solution which have been adopted for the problems encountered are emphasied ; the work with high speed camera is presented. The film is illustrated with some fast movie sequences.

  20. Super-rapid medical film processing system

    International Nuclear Information System (INIS)

    Honda, C.; Iwata, M.; Nozaki, H.

    1988-01-01

    A new super-rapid medical film processing system cuts processing time from 90 to 45 seconds, a critical advantage in traumatic injury, surgical operation, and other time-vital applications. The system consists of new films new processing chemicals (developer and fixer), and a new high-speed medical film processor. The system's creation is made possible by three new technologies. In film, multilayered monodispersed grains reduce processing time. In processing chemicals, an innovative design maximizes processing speed. And in the processor itself, a new drying apparatus increases drying efficiency. Together, these technologies achieve 45-second processing without degradation of image quality

  1. Anomaly cancellation for super-W-gravity

    Energy Technology Data Exchange (ETDEWEB)

    Mansfield, P. (Dept. of Theoretical Physics, Univ. of Oxford (United Kingdom)); Spence, B. (Dept. of Physics, Univ. of Southampton (United Kingdom))

    1991-08-08

    We generalise the description of minimal superconformal models coupled to supergravity, due to Distler, Hlousek and Kawaii, to super-W-gravity. When the chiral algebra is the generalisation of the W-algebra associated to any contragredient Lie superalgebra the total central charge vanishes as a result of Lie superalgebra identities. When the algebra has only fermionic simple roots there is N=1 superconformal invariance and for this case we describe the Lax operators and construct gravitationally dressed primary superfields of weight zero. We also prove the anomaly cancellation associated with the generalised non-abelian Toda theories. (orig.).

  2. Anomaly cancellation for super- W -gravity

    Science.gov (United States)

    Mansfield, P.; Spence, B.

    1991-08-01

    We generalise the description of minimal superconformal models coupled to supergravity, due to Distler, Hlousek and Kawaii, to super- W -gravity. When the chiral algebra is the generalisation of the W-algebra associated to any contragredient Lie superalgebra the total central charge vanishes as a result of Lie superalgebra identities. When the algebra has only fermionic simple roots there is N = 1 superconformal invariance and for this case we describe the Lax operators and construct gravitationally dressed primary superfields of weight zero. We also prove the anomaly cancellation associated with the generalised non-abelian Toda theories. Address from 1 October 1991: Physics Department, Imperial College, London SW7 2BZ, UK.

  3. Anomaly cancellation for super-W-gravity

    International Nuclear Information System (INIS)

    Mansfield, P.; Spence, B.

    1991-01-01

    We generalise the description of minimal superconformal models coupled to supergravity, due to Distler, Hlousek and Kawaii, to super-W-gravity. When the chiral algebra is the generalisation of the W-algebra associated to any contragredient Lie superalgebra the total central charge vanishes as a result of Lie superalgebra identities. When the algebra has only fermionic simple roots there is N=1 superconformal invariance and for this case we describe the Lax operators and construct gravitationally dressed primary superfields of weight zero. We also prove the anomaly cancellation associated with the generalised non-abelian Toda theories. (orig.)

  4. Optical trapping with Super-Gaussian beams

    CSIR Research Space (South Africa)

    Mc

    2013-04-01

    Full Text Available stream_source_info McLaren1_2013.pdf.txt stream_content_type text/plain stream_size 2236 Content-Encoding UTF-8 stream_name McLaren1_2013.pdf.txt Content-Type text/plain; charset=UTF-8 JT2A.34.pdf Optics in the Life... Sciences Congress Technical Digest © 2013 The Optical Society (OSA) Optical trapping with Super-Gaussian beams Melanie McLaren, Thulile Khanyile, Patience Mthunzi and Andrew Forbes* National Laser Centre, Council for Scientific and Industrial Research...

  5. Super computer made with Linux cluster

    International Nuclear Information System (INIS)

    Lee, Jeong Hun; Oh, Yeong Eun; Kim, Jeong Seok

    2002-01-01

    This book consists of twelve chapters, which introduce super computer made with Linux cluster. The contents of this book are Linux cluster, the principle of cluster, design of Linux cluster, general things for Linux, building up terminal server and client, Bear wolf cluster by Debian GNU/Linux, cluster system with red hat, Monitoring system, application programming-MPI, on set-up and install application programming-PVM, with PVM programming and XPVM application programming-open PBS with composition and install and set-up and GRID with GRID system, GSI, GRAM, MDS, its install and using of tool kit

  6. Advantages of super-light structures

    DEFF Research Database (Denmark)

    Hertz, Kristian Dahl

    2009-01-01

    Super-light structures with pearl-chain reinforcement is a new revolutionary technology that opens possibilities of building load-bearing structures much cheaper and with several other advantages compared to traditional constructions of concrete and steel. Some benefits are: 1 Half price or less. 2...... Architectural expressions never seen before. 3 Material savings of more than 50 %. 4 Energy and CO2 savings of more than 50 %. 5 No Scaffolding and cheaper moulds. 6 Improved durability. 7 Extreme thermal insulation. 8 Better indoor-climate. 9 User friendly operation and maintenance. 10 Increased safety...

  7. SPAX - PAX with Super-Pages

    Science.gov (United States)

    Bößwetter, Daniel

    Much has been written about the pros and cons of column-orientation as a means to speed up read-mostly analytic workloads in relational databases. In this paper we try to dissect the primitive mechanisms of a database that help express the coherence of tuples and present a novel way of organizing relational data in order to exploit the advantages of both, the row-oriented and the column-oriented world. As we go, we break with yet another bad habit of databases, namely the equal granularity of reads and writes which leads us to the introduction of consecutive clusters of disk pages called super-pages.

  8. PERFORMANCE ANALYSIS OF MULTI-TURN EXTRACTION FROM THE PROTON SYNCHROTRON TO THE SUPER PROTON SYNCHROTRON

    CERN Document Server

    Abernethy, Samuel

    2016-01-01

    Within CERN's accelerator complex, the extraction from the Proton Synchrotron to the Super Proton Synchrotron has been done using the so-called ``Continuous Transfer" (CT) method since the 1970's. A new technique, known as Multi-Turn Extraction (MTE), has now been implemented and is in full operation. This report examines a holistic performance analysis of the novel technique in multiple aspects of the accelerator complex, as well as a direct comparison with its predecessor, CT, from the implementation of MTE in 2010 until the end of 2015.

  9. Radiation shielding for the Super Collider West Utility region

    International Nuclear Information System (INIS)

    Meinke, R.; Mokhov, N.; Orth, D.; Parker, B.; Plant, D.

    1994-02-01

    Shielding considerations in the 20 x 20-TeV Superconducting Super Collider are strongly correlated with detailed machine specifics in the various accelerator sections. The West Utility, the most complex area of the Collider, concentrates all the major accelerator subsystems in a single area. The beam loss rate and associated radiation levels in this region are anticipated to be quite high, and massive radiation shielding is therefore required to protect personnel, Collider components, and the environment. The challenging task of simultaneously optimizing accelerator design and radiation shielding, both of which are strongly influenced by subsystem design details, requires the integration of several complex simulation codes. To this end we have performed exhaustive hadronic shower simulations with the MARS12 program; detailed accelerator lattice and optics optimization via the SYNCH, MAD, and MAGIC codes; and extensive 3-D configuration modeling of the accelerator tunnel and subsystems geometries. Our technique and the non-trivial results from such a combined approach are presented here. An integrated procedure is found invaluable in developing cost-effective radiation shielding solutions

  10. Deriving Global Convection Maps From SuperDARN Measurements

    Science.gov (United States)

    Gjerloev, J. W.; Waters, C. L.; Barnes, R. J.

    2018-04-01

    A new statistical modeling technique for determining the global ionospheric convection is described. The principal component regression (PCR)-based technique is based on Super Dual Auroral Radar Network (SuperDARN) observations and is an advanced version of the PCR technique that Waters et al. (https//:doi.org.10.1002/2015JA021596) used for the SuperMAG data. While SuperMAG ground magnetic field perturbations are vector measurements, SuperDARN provides line-of-sight measurements of the ionospheric convection flow. Each line-of-sight flow has a known azimuth (or direction), which must be converted into the actual vector flow. However, the component perpendicular to the azimuth direction is unknown. Our method uses historical data from the SuperDARN database and PCR to determine a fill-in model convection distribution for any given universal time. The fill-in data process is driven by a list of state descriptors (magnetic indices and the solar zenith angle). The final solution is then derived from a spherical cap harmonic fit to the SuperDARN measurements and the fill-in model. When compared with the standard SuperDARN fill-in model, we find that our fill-in model provides improved solutions, and the final solutions are in better agreement with the SuperDARN measurements. Our solutions are far less dynamic than the standard SuperDARN solutions, which we interpret as being due to a lack of magnetosphere-ionosphere inertia and communication delays in the standard SuperDARN technique while it is inherently included in our approach. Rather, we argue that the magnetosphere-ionosphere system has inertia that prevents the global convection from changing abruptly in response to an interplanetary magnetic field change.

  11. SuperJet International case study: a business network start-up in the aeronautics industry

    Science.gov (United States)

    Corallo, Angelo; de Maggio, Marco; Storelli, Davide

    This chapter presents the SuperJet International case study, a start-up in the aeronautics industry characterized by a process-oriented approach and a complex and as yet evolving network of partnerships and collaborations. The chapter aims to describe the key points of the start-up process, highlighting common factors and differences compared to the TEKNE Methodology of Change, with particular reference to the second and third phase, namely, the design and deployment of new techno-organizational systems. The SuperJet International startup is presented as a case study where strategic and organizational aspects have been jointly conceived from a network-driven perspective. The chapter compares some of the guidelines of the TEKNE Methodology of Change with experiences and actual practices deriving from interviews with key players in SJI's start-up process.

  12. 3D super-virtual refraction interferometry

    KAUST Repository

    Lu, Kai

    2014-08-05

    Super-virtual refraction interferometry enhances the signal-to-noise ratio of far-offset refractions. However, when applied to 3D cases, traditional 2D SVI suffers because the stationary positions of the source-receiver pairs might be any place along the recording plane, not just along a receiver line. Moreover, the effect of enhancing the SNR can be limited because of the limitations in the number of survey lines, irregular line geometries, and azimuthal range of arrivals. We have developed a 3D SVI method to overcome these problems. By integrating along the source or receiver lines, the cross-correlation or the convolution result of a trace pair with the source or receiver at the stationary position can be calculated without the requirement of knowing the stationary locations. In addition, the amplitudes of the cross-correlation and convolution results are largely strengthened by integration, which is helpful to further enhance the SNR. In this paper, both synthetic and field data examples are presented, demonstrating that the super-virtual refractions generated by our method have accurate traveltimes and much improved SNR.

  13. Intermediate heat exchanger project for Super Phenix

    International Nuclear Information System (INIS)

    Roumailhac, J.; Desir, D.

    1975-01-01

    The Super Phenix (1200 MWe) intermediate heat exchangers are derived directly from those of Phenix (250 MWe). The intermediate exchangers are housed in the reactor vessel annulus: as this annulus must be of the smallest volume possible, these IHX are required to work at a high specific rating. The exchange surface is calculated for nominal conditions. A range is then defined, consistent with the above requirements and throughout which the ratio between bundle thickness and bundle length remains acceptable. Experimental technics and calculations were used to determine the number of tube constraint systems required to keep the vibration amplitude within permissible limits. From a knowledge of this number, the pressure drop produced by the primary flow can be calculated. The bundle geometry is determined together with the design of the corresponding tube plates and the way in which these plates should be joined to the body of the IHX. The experience (technical and financial) acquired in the construction of Phenix is then used to optimize the design of the Super Phenix project. An approximate definition of the structure of the IHX is obtained by assuming a simplified load distribution in the calculations. More sophisticated calculations (e.g. finite element method) are then used to determine the behaviour of the different points of the IHX, under nominal and transient conditions

  14. Review of Super Crunchers by Ian Ayers

    Directory of Open Access Journals (Sweden)

    Eric Gaze

    2009-07-01

    Full Text Available Ayers, I. Super Crunchers: Why Thinking-by-Numbers Is the New Way to be Smart. (Bantam Dell Publishing Group, 2007. 272 pp. Hard cover $25 ISBN 978-0-553-80540-6.Super Crunchers tells the story of how analyzing data is changing the ways in which decisions are made. We in the National Numeracy Network make a case for the importance of quantitative literacy by referring to how much quantitative information is now available to each of us: “a world awash in numbers.” Ian Ayres zeroes in on the people who are making a living crunching all of these data. From the seemingly innocuous (how wines are rated, and the scouting of baseball players to the life impacting (diagnosis of disease, and parole of inmates, this book paints a vivid portrayal of how data analysis is impacting decision making at every level in our society. The use of simple regression models and randomized trials is calling into question who the “experts” of the twenty-first century will be, and why thinking-by-numbers really is the new way to be smart.

  15. Super high field ohmically heated tokamak operation

    International Nuclear Information System (INIS)

    Cohn, D.R.; Bromberg, L.; Leclaire, R.J.; Potok, R.E.; Jassby, D.L.

    1986-01-01

    The authors discuss a super high field mode of tokamak operation that uses ohmic heating or near ohmic heating to ignition. The super high field mode of operation uses very high values of Β/sup 2/α, where Β is the magnetic field and a is the minor radius (Β/sup 2/α > 100 T/sup 2/m). We analyze copper magnet devices with major radii from 1.7 to 3.0 meters. Minimizing or eliminating the need for auxiliary heating has the potential advantages of reducing uncertainty in extrapolating the energy confinement time of current tokamak devices, and reducing engineering problems associated with large auxiliary heating requirements. It may be possible to heat relatively short pulse, inertially cooled tokamaks to ignition with ohmic power alone. However, there may be advantages in using a very small amount of auxiliary power (less than the ohmic heating power) to boost the ohmic heating and provide a faster start-up, expecially in relatively compact devices

  16. Sala polideportiva de Super-Lioran Francia

    Directory of Open Access Journals (Sweden)

    Mazzucconi, Vittorio

    1980-12-01

    Full Text Available The polysports hall of the Super-Lioran winter resort, located in a crater filled with aliuvionary deposits, consists of two clearly differentiated parts: a lower one, of concrete, where there is the skating rink and various services, and an upper one consisting of hyperbolic paraboloid elements. This roof is of adhered laminate wood. The laminate roof structure rests on the ground, and almost merges with it, to later emerge from the snow giving the assembly almost an abstract nature which helps to increase the beauty of the area.

    La sala polideportiva de la estación invernal de Super-Lioran, situada en un cráter relleno de depósitos aluvionares, consta de dos partes claramente diferenciadas: una inferior, de hormigón, donde se encuentran la pista de patinaje y los distintos servicios, y una superior formada por elementos de paraboloide hiperbólico. Esta cubierta es de madera laminada encolada. La estructura laminar de la cubierta se apoya en el suelo casi confundiéndose con él, y luego emerge desde la nieve proporcionando al conjunto un carácter casi abstracto que contribuye a aumentar la belleza de la zona.

  17. Super Talbot effect in indefinite metamaterial.

    Science.gov (United States)

    Zhao, Wangshi; Huang, Xiaoyue; Lu, Zhaolin

    2011-08-01

    The Talbot effect (or the self-imaging effect) can be observed for a periodic object with a pitch larger than the diffraction limit of an imaging system, where the paraxial approximation is applied. In this paper, we show that the super Talbot effect can be achieved in an indefinite metamaterial even when the period is much smaller than the diffraction limit in both two-dimensional and three-dimensional numerical simulations, where the paraxial approximation is not applied. This is attributed to the evanescent waves, which carry the information about subwavelength features of the object, can be converted into propagating waves and then conveyed to far field by the metamaterial, where the permittivity in the propagation direction is negative while the transverse ones are positive. The indefinite metamaterial can be approximated by a system of thin, alternating multilayer metal and insulator (MMI) stack. As long as the loss of the metamaterial is small enough, deep subwavelength image size can be obtained in the super Talbot effect.

  18. Chromatin Constrains the Initiation and Elongation of DNA Replication.

    Science.gov (United States)

    Devbhandari, Sujan; Jiang, Jieqing; Kumar, Charanya; Whitehouse, Iestyn; Remus, Dirk

    2017-01-05

    Eukaryotic chromosomal DNA is faithfully replicated in a complex series of cell-cycle-regulated events that are incompletely understood. Here we report the reconstitution of DNA replication free in solution with purified proteins from the budding yeast Saccharomyces cerevisiae. The system recapitulates regulated bidirectional origin activation; synthesis of leading and lagging strands by the three replicative DNA polymerases Pol α, Pol δ, and Pol ε; and canonical maturation of Okazaki fragments into continuous daughter strands. We uncover a dual regulatory role for chromatin during DNA replication: promoting origin dependence and determining Okazaki fragment length by restricting Pol δ progression. This system thus provides a functional platform for the detailed mechanistic analysis of eukaryotic chromosome replication. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. A morphospace for reef fishes: elongation is the dominant axis of body shape evolution.

    Directory of Open Access Journals (Sweden)

    Thomas Claverie

    Full Text Available Tropical reef fishes are widely regarded as being perhaps the most morphologically diverse vertebrate assemblage on earth, yet much remains to be discovered about the scope and patterns of this diversity. We created a morphospace of 2,939 species spanning 56 families of tropical Indo-Pacific reef fishes and established the primary axes of body shape variation, the phylogenetic consistency of these patterns, and whether dominant patterns of shape change can be accomplished by diverse underlying changes. Principal component analysis showed a major axis of shape variation that contrasts deep-bodied species with slender, elongate forms. Furthermore, using custom methods to compare the elongation vector (axis that maximizes elongation deformation and the main vector of shape variation (first principal component for each family in the morphospace, we showed that two thirds of the families diversify along an axis of body elongation. Finally, a comparative analysis using a principal coordinate analysis based on the angles among first principal component vectors of each family shape showed that families accomplish changes in elongation with a wide range of underlying modifications. Some groups such as Pomacentridae and Lethrinidae undergo decreases in body depth with proportional increases in all body regions, while other families show disproportionate changes in the length of the head (e.g., Labridae, the trunk or caudal region in all combinations (e.g., Pempheridae and Pinguipedidae. In conclusion, we found that evolutionary changes in body shape along an axis of elongation dominates diversification in reef fishes. Changes in shape on this axis are thought to have immediate implications for swimming performance, defense from gape limited predators, suction feeding performance and access to some highly specialized habitats. The morphological modifications that underlie changes in elongation are highly diverse, suggesting a role for a range of

  20. A Morphospace for Reef Fishes: Elongation Is the Dominant Axis of Body Shape Evolution

    Science.gov (United States)

    Claverie, Thomas; Wainwright, Peter C.

    2014-01-01

    Tropical reef fishes are widely regarded as being perhaps the most morphologically diverse vertebrate assemblage on earth, yet much remains to be discovered about the scope and patterns of this diversity. We created a morphospace of 2,939 species spanning 56 families of tropical Indo-Pacific reef fishes and established the primary axes of body shape variation, the phylogenetic consistency of these patterns, and whether dominant patterns of shape change can be accomplished by diverse underlying changes. Principal component analysis showed a major axis of shape variation that contrasts deep-bodied species with slender, elongate forms. Furthermore, using custom methods to compare the elongation vector (axis that maximizes elongation deformation) and the main vector of shape variation (first principal component) for each family in the morphospace, we showed that two thirds of the families diversify along an axis of body elongation. Finally, a comparative analysis using a principal coordinate analysis based on the angles among first principal component vectors of each family shape showed that families accomplish changes in elongation with a wide range of underlying modifications. Some groups such as Pomacentridae and Lethrinidae undergo decreases in body depth with proportional increases in all body regions, while other families show disproportionate changes in the length of the head (e.g., Labridae), the trunk or caudal region in all combinations (e.g., Pempheridae and Pinguipedidae). In conclusion, we found that evolutionary changes in body shape along an axis of elongation dominates diversification in reef fishes. Changes in shape on this axis are thought to have immediate implications for swimming performance, defense from gape limited predators, suction feeding performance and access to some highly specialized habitats. The morphological modifications that underlie changes in elongation are highly diverse, suggesting a role for a range of developmental processes

  1. Impaired rate of microsomal fatty acid elongation in undernourished neonatal rat brain

    International Nuclear Information System (INIS)

    Yeh, Y.Y.

    1986-01-01

    Hypomyelination caused by undernourishment in characterized by low concentrations of myelin lipids and marked reduction in lignocerate (C/sub 24:0/) and nervonate (C/sub 24:1/) moiety of cerebroside and sulfatide. Since microsomal elongation is the major source of long chain (22 to 24 carbons) fatty acids in the brain, the effect of neonatal undernourishment on acyl elongation was investigated. Undernourishment of suckling rats were induced after birth by restricting maternal dietary intake to 40% of that consumed by dams fed ad libitum. Neonates suckled by the normally fed dams served as controls. Microsomal elongation was measured as nmol from [2- 14 C] malonyl CoA incorporated/h per mg of protein. At 19 days of age, rates of behenoyl CoA (C/sub 22:0/) and erucoyl CoA (C/sub 22:1/) elongation in whole brain of undernourished neonates were 30-40% lower than that of the control, whereas the elongation rates of acyl CoA 16, 18 and 20 carbons in length either saturated or monounsaturated were similar in both groups. Undernourishment had no effect on cytoplasmic de novo fatty acid synthesis from acetyl CoA. If there are multiple elongation factors, the results indicate that the depressed activity of elongating enzyme(s) for C/sub 22:0/ and C/sub 22:1/ is an important contributing factor in lowering S/sub 24:0/ and C/sub 24:1/ content in cerebroside and sulfatide. This impairment may be a specific lesion leading to hypomyelination in undernourished rats

  2. Branch Point Withdrawal in Elongational Startup Flow by Time-Resolved Small Angle Neutron Scattering

    KAUST Repository

    Ruocco, N.; Auhl, D.; Bailly, C.; Lindner, P.; Pyckhout-Hintzen, W.; Wischnewski, A.; Leal, L. G.; Hadjichristidis, Nikolaos; Richter, D.

    2016-01-01

    We present a small angle neutron scattering (SANS) investigation of a blend composed of a dendritic polymer and a linear matrix with comparable viscosity in start-up of an elongational flow at Tg + 50. The two-generation dendritic polymer is diluted to 10% by weight in a matrix of a long well-entangled linear chains. Both components consist of mainly 1,4-cis-polyisoprene but differ in isotopic composition. The resulting scattering contrast is sufficiently high to permit time-resolved measurements of the system structure factor during the start-up phase and to follow the retraction processes involving the inner sections of the branched polymer in the nonlinear deformation response. The outer branches and the linear matrix, on the contrary, are in the linear deformation regime. The linear matrix dominates the rheological signature of the blend and the influence of the branched component can barely be detected. However, the neutron scattering intensity is predominantly that of the (branched) minority component so that its dynamics is clearly evident. In the present paper, we use the neutron scattering data to validate the branch point withdrawal process, which could not be unambiguously discerned from rheological measurements in this blend. The maximal tube stretch that the inner branches experience, before the relaxed outer arm material is incorporated into the tube is determined. The in situ scattering experiments demonstrate for the first time the leveling-off of the strain as the result of branch point withdrawal and chain retraction directly on the molecular level. We conclude that branch point motion in the mixture of architecturally complex polymers occurs earlier than would be expected in a purely branched system, presumably due to the different topological environment that the linear matrix presents to the hierarchically deep-buried tube sections. © 2016 American Chemical Society.

  3. Branch Point Withdrawal in Elongational Startup Flow by Time-Resolved Small Angle Neutron Scattering

    KAUST Repository

    Ruocco, N.

    2016-05-27

    We present a small angle neutron scattering (SANS) investigation of a blend composed of a dendritic polymer and a linear matrix with comparable viscosity in start-up of an elongational flow at Tg + 50. The two-generation dendritic polymer is diluted to 10% by weight in a matrix of a long well-entangled linear chains. Both components consist of mainly 1,4-cis-polyisoprene but differ in isotopic composition. The resulting scattering contrast is sufficiently high to permit time-resolved measurements of the system structure factor during the start-up phase and to follow the retraction processes involving the inner sections of the branched polymer in the nonlinear deformation response. The outer branches and the linear matrix, on the contrary, are in the linear deformation regime. The linear matrix dominates the rheological signature of the blend and the influence of the branched component can barely be detected. However, the neutron scattering intensity is predominantly that of the (branched) minority component so that its dynamics is clearly evident. In the present paper, we use the neutron scattering data to validate the branch point withdrawal process, which could not be unambiguously discerned from rheological measurements in this blend. The maximal tube stretch that the inner branches experience, before the relaxed outer arm material is incorporated into the tube is determined. The in situ scattering experiments demonstrate for the first time the leveling-off of the strain as the result of branch point withdrawal and chain retraction directly on the molecular level. We conclude that branch point motion in the mixture of architecturally complex polymers occurs earlier than would be expected in a purely branched system, presumably due to the different topological environment that the linear matrix presents to the hierarchically deep-buried tube sections. © 2016 American Chemical Society.

  4. Circadian clock gene LATE ELONGATED HYPOCOTYL directly regulates the timing of floral scent emission in Petunia.

    Science.gov (United States)

    Fenske, Myles P; Hewett Hazelton, Kristen D; Hempton, Andrew K; Shim, Jae Sung; Yamamoto, Breanne M; Riffell, Jeffrey A; Imaizumi, Takato

    2015-08-04

    Flowers present a complex display of signals to attract pollinators, including the emission of floral volatiles. Volatile emission is highly regulated, and many species restrict emissions to specific times of the day. This rhythmic emission of scent is regulated by the circadian clock; however, the mechanisms have remained unknown. In Petunia hybrida, volatile emissions are dominated by products of the floral volatile benzenoid/phenylpropanoid (FVBP) metabolic pathway. Here we demonstrate that the circadian clock gene P. hybrida LATE ELONGATED HYPOCOTYL (LHY; PhLHY) regulates the daily expression patterns of the FVBP pathway genes and floral volatile production. PhLHY expression peaks in the morning, antiphasic to the expression of P. hybrida GIGANTEA (PhGI), the master scent regulator ODORANT1 (ODO1), and many other evening-expressed FVBP genes. Overexpression phenotypes of PhLHY in Arabidopsis caused an arrhythmic clock phenotype, which resembles those of LHY overexpressors. In Petunia, constitutive expression of PhLHY depressed the expression levels of PhGI, ODO1, evening-expressed FVBP pathway genes, and FVBP emission in flowers. Additionally, in the Petunia lines in which PhLHY expression was reduced, the timing of peak expression of PhGI, ODO1, and the FVBP pathway genes advanced to the morning. Moreover, PhLHY protein binds to cis-regulatory elements called evening elements that exist in promoters of ODO1 and other FVBP genes. Thus, our results imply that PhLHY directly sets the timing of floral volatile emission by restricting the expression of ODO1 and other FVBP genes to the evening in Petunia.

  5. Analysing 'super-participation' in online third spaces

    NARCIS (Netherlands)

    Graham, Todd; Wright, Scott; Cantijoch, Marta; Gibson, Rachel; Ward, Stephen

    2014-01-01

    This chapter focuses on our attempts to overcome the methodological challenges of 'super-participation' in online discussion forums, focusing on the participatory patterns and discursive activity of what we call 'super-participants'. Our principal contribution in this area (Graham and Wright 2013)

  6. RF system for the super conducting proton linac

    International Nuclear Information System (INIS)

    Touchi, Y.

    2001-01-01

    In this paper, we introduce the several types of RF sources used for proton liner accelerators. Also we discus the undesirable characteristics of super-conducting cavities, and the influence of the large beam loading for an accelerating field. We propose the RF system for the super-conducting proton linear accelerators using the Diacrode or IOT taking these effects into account. (author)

  7. Example-Based Super-Resolution Fluorescence Microscopy.

    Science.gov (United States)

    Jia, Shu; Han, Boran; Kutz, J Nathan

    2018-04-23

    Capturing biological dynamics with high spatiotemporal resolution demands the advancement in imaging technologies. Super-resolution fluorescence microscopy offers spatial resolution surpassing the diffraction limit to resolve near-molecular-level details. While various strategies have been reported to improve the temporal resolution of super-resolution imaging, all super-resolution techniques are still fundamentally limited by the trade-off associated with the longer image acquisition time that is needed to achieve higher spatial information. Here, we demonstrated an example-based, computational method that aims to obtain super-resolution images using conventional imaging without increasing the imaging time. With a low-resolution image input, the method provides an estimate of its super-resolution image based on an example database that contains super- and low-resolution image pairs of biological structures of interest. The computational imaging of cellular microtubules agrees approximately with the experimental super-resolution STORM results. This new approach may offer potential improvements in temporal resolution for experimental super-resolution fluorescence microscopy and provide a new path for large-data aided biomedical imaging.

  8. Shedding light on endocytosis with optimized super-resolution microscopy

    NARCIS (Netherlands)

    Leyton Puig, D.M.

    2017-01-01

    Super-resolution microscopy is a relatively new microscopy technique that is still under optimization. In this thesis we focus on the improvement of the quality of super-resolution images, to apply them to the study of the processes of cell signaling and endocytosis. First, we show that the use of a

  9. Super Bowli teooria soovitab aktsiaid osta / Fredy-Edwin Esse

    Index Scriptorium Estoniae

    Esse, Fredy-Edwin

    2011-01-01

    Super Bowli teooria kohaselt tõuseb Dow Jones, kui võidab algupärase NFL-i meeskond. MarketWatchi peaökonomist Irwin Keller avaldab arvamust, miks tasuks investoritel Super Bowli tulemustele tähelepanu pöörata

  10. Autonomous Operation of Super-Regenerative Receiver in BAN

    NARCIS (Netherlands)

    Kalyanasundaram, P.; Huang, L.; Dolmans, G.; Imamura, K.

    2012-01-01

    Super-regenerative receiver is one of the potential candidates to achieve ultra low power wireless communication in body area network (BAN). The main limitations of the super-regenerative receiver include the difficulty in choosing a good quench waveform to optimize its sensitivity and selectivity,

  11. Super-Group Field Cosmology in Batalin-Vilkovisky Formulation

    Science.gov (United States)

    Upadhyay, Sudhaker

    2016-09-01

    In this paper we study the third quantized super-group field cosmology, a model in multiverse scenario, in Batalin-Vilkovisky (BV) formulation. Further, we propose the superfield/super-antifield dependent BRST symmetry transformations. Within this formulation we establish connection between the two different solutions of the quantum master equation within the BV formulation.

  12. Steam generator development in France for the Super Phenix project

    International Nuclear Information System (INIS)

    Robin, M.G.

    1975-01-01

    'Steam Generator Development for Super Phenix Project'. The development program of steam generators studied by Fives-Cail Babcock and Stein Industrie Companies, jointly with CEA end EDF, for the Super Phenix 1200 MWe Fast Breeder Power Plant, is presented. The main characteristics of both sodium heated steam generators are emphasized and experimental studies related to their key features are reported. (author)

  13. Team Performance and Sport Attendance of South African Super ...

    African Journals Online (AJOL)

    In professional rugby, competitions such as the Super Rugby and Currie Cup benefit from the lucrative money-generating opportunities offered. This study focuses on team performance and spectator attendance of the Super Rugby and Currie Cup competitions. Results indicated some interesting relationships between ...

  14. Nonlinear super-W algebras at fixed central charge

    NARCIS (Netherlands)

    Bergshoeff, E.

    1991-01-01

    We discuss how a class of nonlinear higher-spin superalgebras, containing a Virasoro subalgebra at fixed central charge, can be obtained from a realisation of the super-W∞(λ) algebra in terms of a supersymmetric BC system. We explicitly work out the example of the nonlinear super-W2 algebra.

  15. Adherens junction distribution mechanisms during cell-cell contact elongation in Drosophila.

    Directory of Open Access Journals (Sweden)

    Gabrielle Goldenberg

    Full Text Available During Drosophila gastrulation, amnioserosa (AS cells flatten and spread as an epithelial sheet. We used AS morphogenesis as a model to investigate how adherens junctions (AJs distribute along elongating cell-cell contacts in vivo. As the contacts elongated, total AJ protein levels increased along their length. However, genetically blocking this AJ addition indicated that it was not essential for maintaining AJ continuity. Implicating other remodeling mechanisms, AJ photobleaching revealed non-directional lateral mobility of AJs along the elongating contacts, as well as local AJ removal from the membranes. Actin stabilization with jasplakinolide reduced AJ redistribution, and live imaging of myosin II along elongating contacts revealed fragmented, expanding and contracting actomyosin networks, suggesting a mechanism for lateral AJ mobility. Actin stabilization also increased total AJ levels, suggesting an inhibition of AJ removal. Implicating AJ removal by endocytosis, clathrin endocytic machinery accumulated at AJs. However, dynamin disruption had no apparent effect on AJs, suggesting the involvement of redundant or dynamin-independent mechanisms. Overall, we propose that new synthesis, lateral diffusion, and endocytosis play overlapping roles to populate elongating cell-cell contacts with evenly distributed AJs in this in vivo system.

  16. Codon usage regulates protein structure and function by affecting translation elongation speed in Drosophila cells.

    Science.gov (United States)

    Zhao, Fangzhou; Yu, Chien-Hung; Liu, Yi

    2017-08-21

    Codon usage biases are found in all eukaryotic and prokaryotic genomes and have been proposed to regulate different aspects of translation process. Codon optimality has been shown to regulate translation elongation speed in fungal systems, but its effect on translation elongation speed in animal systems is not clear. In this study, we used a Drosophila cell-free translation system to directly compare the velocity of mRNA translation elongation. Our results demonstrate that optimal synonymous codons speed up translation elongation while non-optimal codons slow down translation. In addition, codon usage regulates ribosome movement and stalling on mRNA during translation. Finally, we show that codon usage affects protein structure and function in vitro and in Drosophila cells. Together, these results suggest that the effect of codon usage on translation elongation speed is a conserved mechanism from fungi to animals that can affect protein folding in eukaryotic organisms. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  17. Restricted cell elongation in Arabidopsis hypocotyls is associated with a reduced average pectin esterification level

    Directory of Open Access Journals (Sweden)

    Derbyshire Paul

    2007-06-01

    Full Text Available Abstract Background Cell elongation is mainly limited by the extensibility of the cell wall. Dicotyledonous primary (growing cell walls contain cellulose, xyloglucan, pectin and proteins, but little is known about how each polymer class contributes to the cell wall mechanical properties that control extensibility. Results We present evidence that the degree of pectin methyl-esterification (DE% limits cell growth, and that a minimum level of about 60% DE is required for normal cell elongation in Arabidopsis hypocotyls. When the average DE% falls below this level, as in two gibberellic acid (GA mutants ga1-3 and gai, and plants expressing pectin methyl-esterase (PME1 from Aspergillus aculeatus, then hypocotyl elongation is reduced. Conclusion Low average levels of pectin DE% are associated with reduced cell elongation, implicating PMEs, the enzymes that regulate DE%, in the cell elongation process and in responses to GA. At high average DE% other components of the cell wall limit GA-induced growth.

  18. The high temperature out-of-pile test of LVDT for elongation measurement of fuel pellet

    Energy Technology Data Exchange (ETDEWEB)

    Son, J. M.; Kim, B. K.; Jo, M. S.; Joo, K. N.; Park, S. J.; Gang, Y. H.; Kim, Y. J. [KAERI, Taejon (Korea, Republic of)

    2003-10-01

    As a part of the development of instrumentation technologies for the nuclear fuel irradiation test in HANARO(High-flux Advanced Nuclear Application Reactor), the elongation measurement technique of the fuel pellet is being developed using LVDT(Linear Variable Differential Transformer). The well qualified out-of-pile test were needed to understand the LVDT's detail characteristics at high temperature for the detail design of the fuel irradiation instrumented capsule, because LVDT is very sensitive to variation of temperature. Therefore, the high temperature out-of-pile test system for fuel pellet elongation was developed, and this test was performed under the temperature condition between room temperature and 300 .deg. C with increasing the elongation from 0 to 5 mm. The LVDT's high temperature characteristics and temperature sensitivity of LVDT were analyzed through this experiment. Based on the result of this test, the method for the application of LVDT and elongation detector at high temperature was introduced. It is known that the results will be used to predict accurately the elongation of fuel pellet during irradiation test.

  19. Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis

    Science.gov (United States)

    González-Terán, Bárbara; Cortés, José R.; Manieri, Elisa; Matesanz, Nuria; Verdugo, ρngeles; Rodríguez, María E.; González-Rodríguez, ρgueda; Valverde, ρngela; Martín, Pilar; Davis, Roger J.; Sabio, Guadalupe

    2012-01-01

    Bacterial LPS (endotoxin) has been implicated in the pathogenesis of acute liver disease through its induction of the proinflammatory cytokine TNF-α. TNF-α is a key determinant of the outcome in a well-established mouse model of acute liver failure during septic shock. One possible mechanism for regulating TNF-α expression is through the control of protein elongation during translation, which would allow rapid cell adaptation to physiological changes. However, the regulation of translational elongation is poorly understood. We found that expression of p38γ/δ MAPK proteins is required for the elongation of nascent TNF-α protein in macrophages. The MKK3/6-p38γ/δ pathway mediated an inhibitory phosphorylation of eukaryotic elongation factor 2 (eEF2) kinase, which in turn promoted eEF2 activation (dephosphorylation) and subsequent TNF-α elongation. These results identify a new signaling pathway that regulates TNF-α production in LPS-induced liver damage and suggest potential cell-specific therapeutic targets for liver diseases in which TNF-α production is involved. PMID:23202732

  20. The effect of heat and radiation on the initiation and elongation processes of DNA synthesis

    International Nuclear Information System (INIS)

    Davies, R.C.; Bowden, G.T.; Cress, A.E.

    1983-01-01

    The pH step alkaline elution and alkaline sucrose gradient techniques were utilized to evaluate alterations in DNA replication (initiation and elongation) induced by heat and low dose X-irradiation in synchronized Chinese hamster ovary cells. The initiation and elongation processes of DNA synthesis were radioresistant at the G 1 /S boundary (4 hours after mitosis) while in mid S phase (9 hours after mitosis) DNA initiation and elongation were sensitive to X-irradiation. The initiation and elongation processes of DNA synthesis which were radiation resistant at the G 1 /S boundary could be inhibited by a hyperthermia treatment (43 0 C for 1 hour beginning at 4 hours after mitosis). The impairment of initiation in the heated cells was maintained through late S phase while that of elongation was reversible as judged by full recovery at 15 hours after mitosis. These data suggest that the known synergistic lethality of heat and radiation may be mediated by an impairment of initiation of DNA synthesis. (author)

  1. Influence of ovarian muscle contraction and oocyte growth on egg chamber elongation in Drosophila.

    Science.gov (United States)

    Andersen, Darcy; Horne-Badovinac, Sally

    2016-04-15

    Organs are formed from multiple cell types that make distinct contributions to their shape. The Drosophila egg chamber provides a tractable model to dissect such contributions during morphogenesis. Egg chambers consist of 16 germ cells (GCs) surrounded by a somatic epithelium. Initially spherical, these structures elongate as they mature. This morphogenesis is thought to occur through a 'molecular corset' mechanism, whereby structural elements within the epithelium become circumferentially organized perpendicular to the elongation axis and resist the expansive growth of the GCs to promote elongation. Whether this epithelial organization provides the hypothesized constraining force has been difficult to discern, however, and a role for GC growth has not been demonstrated. Here, we provide evidence for this mechanism by altering the contractile activity of the tubular muscle sheath that surrounds developing egg chambers. Muscle hypo-contraction indirectly reduces GC growth and shortens the egg, which demonstrates the necessity of GC growth for elongation. Conversely, muscle hyper-contraction enhances the elongation program. Although this is an abnormal function for this muscle, this observation suggests that a corset-like force from the egg chamber's exterior could promote its lengthening. These findings highlight how physical contributions from several cell types are integrated to shape an organ. © 2016. Published by The Company of Biologists Ltd.

  2. Abscisic Acid Regulates Auxin Homeostasis in Rice Root Tips to Promote Root Hair Elongation

    Directory of Open Access Journals (Sweden)

    Tao Wang

    2017-06-01

    Full Text Available Abscisic acid (ABA plays an essential role in root hair elongation in plants, but the regulatory mechanism remains to be elucidated. In this study, we found that exogenous ABA can promote rice root hair elongation. Transgenic rice overexpressing SAPK10 (Stress/ABA-activated protein kinase 10 had longer root hairs; rice plants overexpressing OsABIL2 (OsABI-Like 2 had attenuated ABA signaling and shorter root hairs, suggesting that the effect of ABA on root hair elongation depends on the conserved PYR/PP2C/SnRK2 ABA signaling module. Treatment of the DR5-GUS and OsPIN-GUS lines with ABA and an auxin efflux inhibitor showed that ABA-induced root hair elongation depends on polar auxin transport. To examine the transcriptional response to ABA, we divided rice root tips into three regions: short root hair, long root hair and root tip zones; and conducted RNA-seq analysis with or without ABA treatment. Examination of genes involved in auxin transport, biosynthesis and metabolism indicated that ABA promotes auxin biosynthesis and polar auxin transport in the root tip, which may lead to auxin accumulation in the long root hair zone. Our findings shed light on how ABA regulates root hair elongation through crosstalk with auxin biosynthesis and transport to orchestrate plant development.

  3. Steam generator development in France for the Super Phenix project; Generateurs de vapeur developpes en France pour Super Phenix

    Energy Technology Data Exchange (ETDEWEB)

    Robin, M G

    1975-07-01

    'Steam Generator Development for Super Phenix Project'. The development program of steam generators studied by Fives-Cail Babcock and Stein Industrie Companies, jointly with CEA end EDF, for the Super Phenix 1200 MWe Fast Breeder Power Plant, is presented. The main characteristics of both sodium heated steam generators are emphasized and experimental studies related to their key features are reported. (author)

  4. 75 FR 77670 - SuperMedia, LLC, Formerly Known as Idearc Media, LLC, a Subsidiary of SuperMedia Information...

    Science.gov (United States)

    2010-12-13

    ... Known as Idearc Media, LLC, a Subsidiary of SuperMedia Information Services, LLC Publishing Group, Troy... Subsidiary of SuperMedia Information Services, LLC, Troy, New York, to apply for Trade Adjustment Assistance..., Publishing Group, Troy, New York, who became totally or partially separated from employment on or after...

  5. Toolbox for super-structured and super-structure free multi-disciplinary building spatial design optimisation

    NARCIS (Netherlands)

    Boonstra, S.; van der Blom, K.; Hofmeyer, H.; Emmerich, M.T.M.; van Schijndel, A.W.M.; de Wilde, P.

    2018-01-01

    Multi-disciplinary optimisation of building spatial designs is characterised by large solution spaces. Here two approaches are introduced, one being super-structured and the other super-structure free. Both are different in nature and perform differently for large solution spaces and each requires

  6. Applications of super elasticity in vibrational control

    International Nuclear Information System (INIS)

    Soul, H

    2005-01-01

    In this work, the possibilities of using shape memory alloys (SMA) as passive dampers devices in mechanicals vibrations problems are studied.The property that is exploited is the super elastic effect, by wich strains of the order of 10% can be obtained.The relationship between stress and strain means that this is an inelastic process.Nevertheless when load is removed the material recoveries its original dimension, presenting zero or almost zero permanent strain relative to others common materials, describing in its stress-strain diagram an important hysteretic loop.This features occurs basically because in well suited conditions the SMA can undergo martensitic transformations induced by stress.A series of uniaxial tension tests in commercial NiTi wires are performed, in order to characterize the super elastic behavior of the material.The influence of variables as ambient temperature, strain rate, strain levels and number of tension cycles accumulated are studied paying attention to the dissipative capacity of the material defined by means of the shape of the hysteretic loop.The influence on the damping capacity of the thermal effects associated with the martensitic transformation are evaluated by performing experiments at different transformation rates.Results are rationalized in terms of a model considering the interaction between a source term (heat of transformation), heat convection to the ambient and conduction along the wire.Some numerical results are obtained and discussed. For a performance evaluation in devices applications a simplified model of super elasticity is proposed.Then, the response of an elastic frame structure endowed with SMA tensors is evaluated following the model behavior when seismic movement is imposed at the base.The obtained results verify the possibility of using SMA as kernel elements in vibration control.This conclusion is experimentally verified in a prototype of the structure specially designed and constructed for this work

  7. Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development.

    Directory of Open Access Journals (Sweden)

    Molly Parkyn Schneider

    2017-10-01

    Full Text Available Transmission of malaria parasites relies on the formation of a specialized blood form called the gametocyte. Gametocytes of the human pathogen, Plasmodium falciparum, adopt a crescent shape. Their dramatic morphogenesis is driven by the assembly of a network of microtubules and an underpinning inner membrane complex (IMC. Using super-resolution optical and electron microscopies we define the ultrastructure of the IMC at different stages of gametocyte development. We characterize two new proteins of the gametocyte IMC, called PhIL1 and PIP1. Genetic disruption of PhIL1 or PIP1 ablates elongation and prevents formation of transmission-ready mature gametocytes. The maturation defect is accompanied by failure to form an enveloping IMC and a marked swelling of the digestive vacuole, suggesting PhIL1 and PIP1 are required for correct membrane trafficking. Using immunoprecipitation and mass spectrometry we reveal that PhIL1 interacts with known and new components of the gametocyte IMC.

  8. The elastic buckling of super-graphene and super-square carbon nanotube networks

    International Nuclear Information System (INIS)

    Li Ying; Qiu Xinming; Yin Yajun; Yang Fan; Fan Qinshan

    2010-01-01

    The super-graphene (SG) and super-square (SS) carbon nanotube network are built by the straight single-walled carbon nanotubes and corresponding junctions. The elastic buckling behaviors of these carbon nanotube networks under different boundary conditions are explored through the molecular structural mechanics method. The following results are obtained: (a) The critical buckling forces of the SG and SS networks decrease as the side lengths or aspect ratios of the networks increase. The continuum plate theory could give good predictions to the buckling of the SS network but not the SG network with non-uniform buckling modes. (b) The carbon nanotube networks are more stable structures than the graphene structures with less carbon atoms.

  9. From heavy nuclei to super-heavy nuclei; Des noyaux lourds aux super-lourds

    Energy Technology Data Exchange (ETDEWEB)

    Theisen, Ch

    2003-01-01

    The existence of super-heavy nuclei has been predicted nearly fifty years ago. Due to the strong coulomb repulsion, the stabilisation of these nuclei is possible only through shell effects. The reasons for this fragile stability, as well as the theoretical predictions concerning the position of the island of stability are presented in the first part of this lecture. In the second part, experiments and experimental techniques which have been used to synthesize or search for super-heavy elements are described. Spectroscopic studies performed in very heavy elements are presented in the following section. We close this lecture with techniques that are currently being developed in order to reach the superheavy island and to study the structure of very-heavy nuclei. (author)

  10. Structural behaviour of super-light structures

    DEFF Research Database (Denmark)

    Bagger, Anne; Hertz, Kristian Dahl

    2010-01-01

    structural functions: it leads load to the skeleton, it stabilizes the compression members of the skeleton, and it redistributes loads that are not optimal for the skeleton shape. In this paper, FE analysis is used to investigated the behaviour of a series of SLS beams of concrete, under varying stiffness......A new structural concept, called Super-light Structures (SLS), has recently been invented and patented at the Technical University of Denmark. The basic concept of SLS is to construct a skeleton of a stiff and strong material, such as ordinary or high strength concrete, and stabilize this skeleton...... with a lighter and softer material, such as lightweight concrete. The combined use of stiff and light material in SLS results in structures of high stiffness and low weight. The applied technology and the advantages of SLS are elaborated upon in [1] in these proceedings. The present paper focuses...

  11. Solar neutrino results from Super-Kamiokande

    International Nuclear Information System (INIS)

    Takeuchi, Y.

    2001-01-01

    Latest Super-Kamiokande results of the solar neutrino flux, day/night results, energy spectrum measurements, and oscillation analyses are reported. The observation period spans May 31, 1996 to April 24, 2000, which corresponds to a detector live time of 1117 days. Our preliminary results indicate 1.3σ difference between day and night flux, and the energy spectrum expressed as data/(BP98 SSM) is consistent with a flat spectrum with χ 2 /D.O.F.=13.7/17. Comparing global-flux oscillation analysis and SK day and night spectra, MSW SMA region, Just-So region and 2-flavor sterile solutions are disfavored at 95% C.L. (author)

  12. Simultaneous super-resolution and blind deconvolution

    International Nuclear Information System (INIS)

    Sroubek, F; Flusser, J; Cristobal, G

    2008-01-01

    In many real applications, blur in input low-resolution images is a nuisance, which prevents traditional super-resolution methods from working correctly. This paper presents a unifying approach to the blind deconvolution and superresolution problem of multiple degraded low-resolution frames of the original scene. We introduce a method which assumes no prior information about the shape of degradation blurs and which is properly defined for any rational (fractional) resolution factor. The method minimizes a regularized energy function with respect to the high-resolution image and blurs, where regularization is carried out in both the image and blur domains. The blur regularization is based on a generalized multichannel blind deconvolution constraint. Experiments on real data illustrate robustness and utilization of the method

  13. Conceptual Design for SuperCDMS SNOLAB

    International Nuclear Information System (INIS)

    Brink, Paul

    2012-01-01

    Beyond the present dark matter direct detection experiment at the Soudan underground laboratory, the SuperCDMS Collaboration is engaged in R and D activities for a 100-kg scale germanium dark matter experiment nominally sited at SNOLAB (2070 m overburden of rock). The expected sensitivity after 3 years of running is 3 x 10 -46 cm 2 for the spin-independent cross section, an order of magnitude improvement over present exclusion limits for WIMP masses ∼80 GeV/c 2 . At this depth, and appropriate design of shielding and cryostat, neutron backgrounds will be negligible. The baseline design is an expanded version of CDMS II with Ge substrates (100 x 33 mm discs) instrumented with the iZIP phonon sensor layout to achieve the electron surface-event rejection power required.

  14. Grassmannian approach to super-KP hierarchies

    International Nuclear Information System (INIS)

    Takama, Michiaki.

    1995-06-01

    We present a theory of 'maximal' super-KP (SKP) hierarchy whose flows are maximally extended to include all those of known SKP hierarchies, including, for example, the MRSKP hierarchy of Manin and Radul and the Jacobian SKP (JSKP) introduced by Mulase and Rabin. It is shown that SKP hierarchies has a natural field theoretic description in terms of the B-C system, in analogous way as the ordinary KP hierarchy. For this SKP hierarchy, we construct the vertex operators by using Kac-van de Leur superbosonization. The vertex operators act on the τ-function and then produce the wave function and the dual wave function of the hierarchy. Thereby we achieve the description of the 'maximal' SKP hierarchy in terms of the τ-function, which seemed to be lacking till now. Mutual relations among the SKP hierarchies are clarified. The MRSKP and the JSKP hierarchies are obtained as special cases when the time variables are appropriately restricted. (author)

  15. Pitowsky's Kolmogorovian Models and Super-determinism.

    Science.gov (United States)

    Kellner, Jakob

    2017-01-01

    In an attempt to demonstrate that local hidden variables are mathematically possible, Pitowsky constructed "spin-[Formula: see text] functions" and later "Kolmogorovian models", which employs a nonstandard notion of probability. We describe Pitowsky's analysis and argue (with the benefit of hindsight) that his notion of hidden variables is in fact just super-determinism (and accordingly physically not relevant). Pitowsky's first construction uses the Continuum Hypothesis. Farah and Magidor took this as an indication that at some stage physics might give arguments for or against adopting specific new axioms of set theory. We would rather argue that it supports the opposing view, i.e., the widespread intuition "if you need a non-measurable function, it is physically irrelevant".

  16. Super wideband characteristics of monopolar patch antenna

    Directory of Open Access Journals (Sweden)

    Xi Chen

    2013-12-01

    Full Text Available A simple method of acquiring super wideband characteristics for monopolar patch antenna is proposed. Through adopting a modified cone as feeding and radiating structure, the monopolar patch antenna can reach the impedance bandwidth of more than 1:23.4 for voltage standing wave ratio (VSWR ≤ 2. In the whole operating band, the antenna has the like-monopole omnidirectional radiation patterns and the peak gains of 3.8–8.7 dB. Meanwhile, the height of the antenna is just 0.074λ(c, and the diameter of the radiated body is 0.205λ(c, which is smaller than other ultra-wideband omnidirectional antenna.

  17. Physical Properties of Kepler's Super-Earths

    Science.gov (United States)

    Sasselov, Dimitar D.; Kepler Science Team

    2011-01-01

    Planets in the radius range from about 1.25 to 2 Re, referred to as Super-Earth-sized planets, do not exist in our Solar System. Their physical properties as determined by theoretical modeling are expected to differ in many ways from our Solar System experience. The Kepler Mission is going to discover many such planets and determine their orbits and radii. For some of them follow-up observations may determine masses, and for a few of them asteroseismology of their stars from the Kepler light curve may determine an age. I will discuss theoretical models for such planets and how they could be constrained by the anticipated Kepler Mission observations.

  18. Recent results from the super EBIT

    International Nuclear Information System (INIS)

    Marrs, R.E.

    1995-01-01

    The Super EBIT device at LLNL can produce and trap any highly charged ion at rest in the laboratory, including bare U 92+ ions. Recently, the ionization cross sections for high-Z hydrogenlike ions have been measured for the first time, and measurements of the L-shell ionization cross sections for uranium ions are in progress. The two-electron contributions to the ground state energies of heliumlike ions have been directly measured using a novel technique, and spectra of 2s-2p transitions in highly ionized thorium and uranium have been used to test QED corrections to the energy levels of few electron high-Z ions. A new capability for the study of rare isotopes has been demonstrated. Ion cooling has been used to reduce the thermal broadening of x-ray emission lines to the point where natural line widths can be observed in some cases

  19. Super integrable four-dimensional autonomous mappings

    International Nuclear Information System (INIS)

    Capel, H W; Sahadevan, R; Rajakumar, S

    2007-01-01

    A systematic investigation of the complete integrability of a fourth-order autonomous difference equation of the type w(n + 4) = w(n)F(w(n + 1), w(n + 2), w(n + 3)) is presented. We identify seven distinct families of four-dimensional mappings which are super integrable and have three (independent) integrals via a duality relation as introduced in a recent paper by Quispel, Capel and Roberts (2005 J. Phys. A: Math. Gen. 38 3965-80). It is observed that these seven families can be related to the four-dimensional symplectic mappings with two integrals including all the four-dimensional periodic reductions of the integrable double-discrete modified Korteweg-deVries and sine-Gordon equations treated in an earlier paper by two of us (Capel and Sahadevan 2001 Physica A 289 86-106)

  20. The Superconducting Super Collider (SSC) linac

    International Nuclear Information System (INIS)

    Watson, J.M.

    1990-09-01

    The preliminary design of the 600 MeV H - linac for the Superconducting Super Collider injector is described. The linac must provide a 25 mA beam during 7--35 μs macropulses at Hz within injection bursts. Normalized transverse emittances of less than 0.5 π mm-mrad (rms) are required for injection into the Low Energy Booster synchrotron. Cost, ease of commissioning, and operational reliability are important considerations. The linac will consists of an H - source with electrostatic LEBT, 2.5 MeV radiofrequency quadrupole accelerator, a 70 MeV drift-tube linac, and 530 MeV and the side-coupled linac operates at 1284 MHz. A modest total length of 150 m results from the tradeoff between cost optimization and reliability. The expected performance from beam dynamics simulations and the status of the project are described. 11 refs., 1 fig., 6 tabs

  1. The Superconducting Super Collider: A status report

    International Nuclear Information System (INIS)

    Schwitters, R.F.

    1993-04-01

    The design of the Superconducting Super Collider (SSC) is briefly reviewed, including its key machine parameters. The scientific objectives are twofold: (1) investigation of high-mass, low-rate, rare phenomena beyond the standard model; and (2) investigation of processes within the domain of the standard model. Machine luminosity, a key parameter, is a function of beam brightness and current, and it must be preserved through the injector chain. Features of the various injectors are discussed. The superconducting magnet system is reviewed in terms of model magnet performance, including the highly successful Accelerator System String Test Various magnet design modifications are noted, reflecting minor changes in the collider arcs and improved installation procedures. The paper concludes with construction scenarios and priority issues for ensuring the earliest collider commissioning

  2. The SPL-based Neutrino Super Beam

    CERN Document Server

    Baussan, E; Bobeth, C; Bouquerel, E; Caretta, O; Cupial, P; Davenne, T; Densham, C; Dracos, M; Fitton, M; Gaudiot, G; Kozien, M; Lacny, L; Lepers, B; Longhin, A; Loveridge, P; Osswald, F; Poussot, P; Rooney, M; Skoczen, B; Szybinski, B; Ustrzycka, A; Vassilopoulos, N; Wilcox, D; Wroblewski, A; Wurtz, J; Zeter, V; Zito, M

    2012-01-01

    The EUROnu Super Beam work package has studied a neutrino beam based on SPL at CERN and aimed at MEMPHYS, a large water Cherenkov detector, proposed for the Laboratoire Souterrain de Modane (Fr\\'ejus tunnel, France), with a baseline of 130 km. The aim of this proposed experiment is to study the CP violation in the neutrino sector. In the study reported here, we have developed the conceptual design of the neutrino beam, especially the target and the magnetic focusing device. Indeed, this beam present several unprecedented challenges, like the high primary proton beam power (4 MW), the high repetition rate (50 Hz) and the low energy of the protons (4.5 GeV). The design is completed by a study of all the main component of the system, starting from the transport system to guide the beam to the target up to the beam dump.

  3. Barley Seed Germination/Root Elongation Toxicity Test For Evaluation Of Sludge Pre-Treatment

    DEFF Research Database (Denmark)

    Eriksson, Eva; Kusk, Kresten Ole; Barrett Sørensen, Mie

    Application of sludge from wastewater treatment plants (WWTPs) on agricultural land is an approach for nutrient recycling that rise challenges due to recalcitrant and harmful pollutants. In this study we assessed the feasibility of a seed germination test to evaluate sludge ecotoxicity and compared...... germination responses from two test parameters, root elongation and seed germination (sprouts elongation) of the barley (Hordeum vulgare). 2nd objective was to evaluate sewage sludge pre-treatments at batch-scale of sludge samples from two WWTPs using anaerobic digestion, and thermal and ozonation pre......-treatments. Glyphosate and eco-labelled soil were used as references. Inhibition of germination of seeds exposed to the glyphosate and sludge was registered and thus germination was successfully applied for sludge ecotoxicity assessment, and using the root elongation as the end-point was both faster and more precise...

  4. Cell elongation is an adaptive response for clearing long chromatid arms from the cleavage plane

    Science.gov (United States)

    Kotadia, Shaila; Montembault, Emilie; Sullivan, William

    2012-01-01

    Chromosome segregation must be coordinated with cell cleavage to ensure correct transmission of the genome to daughter cells. Here we identify a novel mechanism by which Drosophila melanogaster neuronal stem cells coordinate sister chromatid segregation with cleavage furrow ingression. Cells adapted to a dramatic increase in chromatid arm length by transiently elongating during anaphase/telophase. The degree of cell elongation correlated with the length of the trailing chromatid arms and was concomitant with a slight increase in spindle length and an enlargement of the zone of cortical myosin distribution. Rho guanine-nucleotide exchange factor (Pebble)–depleted cells failed to elongate during segregation of long chromatids. As a result, Pebble-depleted adult flies exhibited morphological defects likely caused by cell death during development. These studies reveal a novel pathway linking trailing chromatid arms and cortical myosin that ensures the clearance of chromatids from the cleavage plane at the appropriate time during cytokinesis, thus preserving genome integrity. PMID:23185030

  5. Active feedback stabilization of axisymmetric modes in highly elongated tokamak plasmas

    International Nuclear Information System (INIS)

    Ward, D.J.; Hofmann, F.

    1993-07-01

    Active feedback stabilization of the vertical instability is studied for highly elongated tokamak plasmas (1≤κ≤3), and evaluated in particular for the TCV configuration. It is shown that the feedback can strongly affect the form of the eigenfunction for these highly elongated equilibria, and this can have detrimental effects on the ability of the feedback system to properly detect and stabilize the plasma. A calculation of the vertical displacement that uses poloidal flux measurements, poloidal magnetic field measurements, and corrections for the vessel eddy currents and active feedback currents was found to be effective even in the cases with the worst deformations of the eigenfunction. We also examine how these deformations affect differently shaped equilibria, and it is seen that the magnitude of the deformation of the eigenfunction is strongly function of the plasma elongation. (author) 15 figs., 13 refs

  6. The effect of texture, heat treatment and elongation rate on stress corrosion cracking in irradiated zircaloy

    International Nuclear Information System (INIS)

    Pettersson, K.; Stany, W.; Hellstrand, E.

    1979-03-01

    Irradiated zircaloy samples with different textures and heat treatments have been tested concerning stress corrosion. Irradiated samples of Zr-1Nb, pure Zr and beta quenched zircaloy have also been investigated. Stress-relieve annealled zircaloy is even after irradiation more sensitive to stress corrosion than recrystallized zircaloy. Zr-1Nb and beta quenched zircaloy are much more sinsitive to stress corrosion than the samples with different textures. As a rule irradiated zircaloy is sensitive to stress corrosion at stresses far below the yield point. The breaking stress decreases with the elongation rate. The extension of cracks is much faster in irradiated zircaloy than in unirradiated zircaloy. There is no simple failure criterium for irradiated zircaloy. However for a certain stress and a certain elongation rate the probability for a failure before this stress is reached with a constant elongation rate can be given. (E.R.)

  7. DNA damage regulates alternative splicing through changes in POL II elongation

    International Nuclear Information System (INIS)

    Munoz, M.J.; Perez Santangelo, M.S.; De la Mata, M.; Kornblihtt, A.R.

    2008-01-01

    Many apoptotic genes are regulated via alternative splicing (AS) but little is known about the mechanisms controlling AS in stress situations derived from DNA damage. Here we show that ultraviolet (UV) radiation affects co-transcriptional, but not post transcriptional, AS through a systemic mechanism involving a CDK-9-dependent hyper phosphorylation of RNA polymerase II carboxy terminal domain (CTD) and a subsequent and unprecedented inhibition of transcriptional elongation, estimated in vivo and in real time by FRAP. To mimic this hyper phosphorylation we used CTD mutants with serines 2 or 5 substituted by glutamic acids and found that they not only display lower elongation rates but duplicate the effects of UV light on AS in the absence of irradiation. Consistently, substitution of the serines with alanines prevents the UV effect on splicing. These results represent the first in vivo proof of modulation of elongation in response to an environmental signal, affecting in turn the kinetic coupling between transcription and splicing. (authors)

  8. Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data

    DEFF Research Database (Denmark)

    Chen, Yun; Jørgensen, Mette; Kolde, Raivo

    2011-01-01

    of RNAPII stalling. CONCLUSIONS: In this study we introduce a general framework to accurately predict the level of RNAPII recruitment, elongation, stalling and mRNA expression from chromatin signals. The versatility of the method also makes it ideally suited to investigate other genomic data....... strategies are needed to progress from descriptive annotation of data to quantitative, predictive models. RESULTS: Here, we describe a computational framework which with high accuracy can predict the locations of core promoters, the amount of recruited RNAPII at the promoter, the amount of elongating RNAPII...... of these four marks are found to be necessary for recruitment of RNAPII but not sufficient for the elongation. We also show that the spatial distributions of histone marks are almost as predictive as the signal strength and that a set of histone marks immediately downstream of the TSS is highly predictive...

  9. Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti-Cancer Properties.

    Science.gov (United States)

    Krastel, Philipp; Roggo, Silvio; Schirle, Markus; Ross, Nathan T; Perruccio, Francesca; Aspesi, Peter; Aust, Thomas; Buntin, Kathrin; Estoppey, David; Liechty, Brigitta; Mapa, Felipa; Memmert, Klaus; Miller, Howard; Pan, Xuewen; Riedl, Ralph; Thibaut, Christian; Thomas, Jason; Wagner, Trixie; Weber, Eric; Xie, Xiaobing; Schmitt, Esther K; Hoepfner, Dominic

    2015-08-24

    Cultivation of myxobacteria of the Nannocystis genus led to the isolation and structure elucidation of a class of novel cyclic lactone inhibitors of elongation factor 1. Whole genome sequence analysis and annotation enabled identification of the putative biosynthetic cluster and synthesis process. In biological assays the compounds displayed anti-fungal and cytotoxic activity. Combined genetic and proteomic approaches identified the eukaryotic translation elongation factor 1α (EF-1α) as the primary target for this compound class. Nannocystin A (1) displayed differential activity across various cancer cell lines and EEF1A1 expression levels appear to be the main differentiating factor. Biochemical and genetic evidence support an overlapping binding site of 1 with the anti-cancer compound didemnin B on EF-1α. This myxobacterial chemotype thus offers an interesting starting point for further investigations of the potential of therapeutics targeting elongation factor 1. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Inhibition of DNA chain elongation in Chinese hamster cells by damage localized behind the replication fork

    Energy Technology Data Exchange (ETDEWEB)

    Ben-Hur, E [Israel Atomic Energy Commission, Beersheba. Nuclear Research Center-Negev; Hagan, M P [Armed Forces Radiobiology Research Inst., Bethesda, MD (USA)

    1984-05-01

    Chinese hamster fibroblasts were pulse labelled with 5-bromodeoxyuridine and exposed at time intervals (Tsub(i)) to near-ultraviolet (U.V.A.) light in the presence of a bisbenzimidazole derivative (Hoechst 33342). The sensitivity of the cells in terms of colony forming ability fluctuated depending on Tsub(i). Inhibition of DNA synthesis also depended on Tsub(i) and was maximal when Tsub(i)=O. Using the alkaline elution technique it was shown that the effect of a large dose of light was to inhibit both initiation and elongation of DNA chains. These effects were most pronounced for Tsub(i)=O. It is concluded that DNA damage in an active replicon can inhibit initiation of new replicons and that damage localized behind the replication fork can retard elongation of nascent DNA chains. This effect on chain elongation decreases with increased distance of the damage from the replication fork.

  11. The SuperCOSMOS Science Archive

    Science.gov (United States)

    Hambly, N.; Read, M.; Mann, R.; Sutorius, E.; Bond, I.; MacGillivray, H.; Williams, P.; Lawrence, A.

    2004-07-01

    The SuperCOSMOS Sky Survey (SSS {http://www-wfau.roe.ac.uk/sss}; Hambly et al., 2001) consists of digitised scans of Schmidt photographic survey material in a multi-colour (BRI), multi-epoch, uniformly calibrated product. It covers the whole southern hemisphere, with an extension into the north currently underway. Public online access to the 2 Tbytes of SSS pixel data and object catalogues has been available for some time; data are being downloaded at a rate of several gigabytes per week, and many new science results are emerging from community use of the data. In this poster we describe the terabyte-scale SuperCOSMOS Science Archive {http://thoth.roe.ac.uk/ssa} (SSA), which is a recasting of the SSS object catalogue system from flat files into an RDBMS, with an enhanced user interface. We describe some aspects of the hardware and schema design of the SSA, which aims to produce a high performance, VO-compatible database, suitable for data mining by `power users', while maintaining the ease of use praised in the old SSS system. Initially, the SSA will allow access through web forms and a flexible SQL interface. It acts as the prototype for the next generation survey archives to be hosted by the University of Edinburgh's Wide Field Astronomy Unit, such as the WFCAM Science Archive of infrared sky survey data, as well as being a scalability testbed for use by AstroGrid, the UK's Virtual Observatory project. As a result of these roles, it will display subsequently an expanding functionality, as web - and later, Grid - services are deployed on it.

  12. Super-virtual refraction interferometry: Theory

    KAUST Repository

    Bharadwaj, Pawan

    2011-01-01

    Inverting for the subsurface velocity distribution by refraction traveltime tomography is a well-accepted imaging method by both the exploration and earthquake seismology communities. A significant drawback, however, is that the recorded traces become noisier with increasing offset from the source position, and so prevents accurate picking of traveltimes in far-offset traces. To enhance the signal-to-noise ratio of the far-offset traces, we present the theory of super-virtual refraction interferometry where the signal-to-noise ratio (SNR) of far-offset head-wave arrivals can be theoretically increased by a factor proportional to N; here, N is the number of receiver and source positions associated with the recording and generation of the head-wave arrival. There are two steps to this methodology: correlation and summation of the data to generate traces with virtual head-wave arrivals, followed by the convolution of the data with the virtual traces to create traces with super-virtual head-wave arrivals. This method is valid for any medium that generates head-wave arrivals. There are at least three significant benefits to this methodology: 1). enhanced SNR of far-offset traces so the first-arrival traveltimes of the noisy far-offset traces can be more reliably picked to extend the useful aperture of data, 2). the SNR of head waves in a trace that arrive after the first arrival can be enhanced for accurate traveltime picking and subsequent inversion by traveltime tomography, and 3). common receiver-pair gathers can be analyzed to detect the presence of diving waves in the first arrivals, which can be used to assess the nature of the refracting boundary. © 2011 Society of Exploration Geophysicists.

  13. Super symmetry in strong and weak interactions

    International Nuclear Information System (INIS)

    Seshavatharam, U.V.S.; Lakshminarayana, S.

    2010-01-01

    For strong interaction two new fermion mass units 105.32 MeV and 11450 MeV are assumed. Existence of "Integral charge quark bosons", "Integral charge effective quark fermions", "Integral charge (effective) quark fermi-gluons" and "Integral charge quark boso-gluons" are assumed and their masses are estimated. It is noticed that, characteristic nuclear charged fermion is X s · 105.32 = 938.8 MeV and corresponding charged boson is X s (105.32/x) = 415.0 where X s = 8.914 is the inverse of the strong coupling constant and x = 2.26234 is a new number by using which "super symmetry" can be seen in "strong and weak" interactions. 11450 MeV fermion and its boson of mass = 11450/x = 5060 MeV plays a crucial role in "sub quark physics" and "weak interaction". 938.8 MeV strong fermion seems to be the proton. 415 MeV strong boson seems to be the mother of the presently believed 493,496 and 547 MeV etc, strange mesons. With 11450 MeV fermion "effective quark-fermi-gluons" and with 5060 MeV boson "quark boso-gluon masses" are estimated. "Effective quark fermi-gluons" plays a crucial role in ground state charged baryons mass generation. Light quark bosons couple with these charged baryons to form doublets and triplets. "Quark boso-gluons" plays a crucial role in ground state neutral and charged mesons mass generation. Fine and super-fine rotational levels can be given by [I or (I/2)] power(1/4) and [I or (I/2)] power(1/12) respectively. Here, I = n(n+1) and n = 1, 2, 3, … (author)

  14. Radiation pressure in super star cluster formation

    Science.gov (United States)

    Tsang, Benny T.-H.; Milosavljević, Miloš

    2018-05-01

    The physics of star formation at its extreme, in the nuclei of the densest and the most massive star clusters in the universe—potential massive black hole nurseries—has for decades eluded scrutiny. Spectroscopy of these systems has been scarce, whereas theoretical arguments suggest that radiation pressure on dust grains somehow inhibits star formation. Here, we harness an accelerated Monte Carlo radiation transport scheme to report a radiation hydrodynamical simulation of super star cluster formation in turbulent clouds. We find that radiation pressure reduces the global star formation efficiency by 30-35%, and the star formation rate by 15-50%, both relative to a radiation-free control run. Overall, radiation pressure does not terminate the gas supply for star formation and the final stellar mass of the most massive cluster is ˜1.3 × 106 M⊙. The limited impact as compared to in idealized theoretical models is attributed to a radiation-matter anti-correlation in the supersonically turbulent, gravitationally collapsing medium. In isolated regions outside massive clusters, where the gas distribution is less disturbed, radiation pressure is more effective in limiting star formation. The resulting stellar density at the cluster core is ≥108 M⊙ pc-3, with stellar velocity dispersion ≳ 70 km s-1. We conclude that the super star cluster nucleus is propitious to the formation of very massive stars via dynamical core collapse and stellar merging. We speculate that the very massive star may avoid the claimed catastrophic mass loss by continuing to accrete dense gas condensing from a gravitationally-confined ionized phase.

  15. Status of the SuperHILAC

    International Nuclear Information System (INIS)

    Grunder, H.A.; Selph, F.B.

    1976-09-01

    The SuperHILAC is an Alvarez linear accelerator designed to accelerate all ions to a maximum energy of 8.5 MeV/u. It functions as an essential part of two research programs of national importance--first, as a supplier of beams for research at less than 10 MeV/u, secondly as an injector for the Bevalac facility, for nuclear physics and medical research at energies greater than 200 MeV/u. This duplication of effort from a single accelerator is made possible by the utilization of a technique known as timeshare--two different ion beams are accelerated independently through the same linac structure. Recent operation has been in the mass range 12 less than or equal to A less than or equal to 136. Usually, a heavy ion (A greater than 40) is delivered to the SuperHILAC experimental area for nuclear physics experiments while concurrently delivering a lighter ion (A less than or equal to 40) to the Bevatron for further acceleration (max. 2.5 GeV/u) to be used in experiments exploring the physics of very high energy heavy ions, in investigations of radiation biology, and in preclinical tests as a tool for cancer treatment. Recent operating experience is reviewed. Also discussed are recent major improvements which have been made to the accelerator, and a proposed improvement which will increase reliability and beam intensity for the very heavy ions (A greater than or equal to 84) by adding a third injector of improved design

  16. DNA Double Strand Break Response and Limited Repair Capacity in Mouse Elongated Spermatids

    Directory of Open Access Journals (Sweden)

    Emad A. Ahmed

    2015-12-01

    Full Text Available Spermatids are extremely sensitive to genotoxic exposures since during spermiogenesis only error-prone non homologous end joining (NHEJ repair pathways are available. Hence, genomic damage may accumulate in sperm and be transmitted to the zygote. Indirect, delayed DNA fragmentation and lesions associated with apoptotic-like processes have been observed during spermatid elongation, 27 days after irradiation. The proliferating spermatogonia and early meiotic prophase cells have been suggested to retain a memory of a radiation insult leading later to this delayed fragmentation. Here, we used meiotic spread preparations to localize phosphorylate histone H2 variant (γ-H2AX foci marking DNA double strand breaks (DSBs in elongated spermatids. This technique enabled us to determine the background level of DSB foci in elongated spermatids of RAD54/RAD54B double knockout (dko mice, severe combined immunodeficiency SCID mice, and poly adenosine diphosphate (ADP-ribose polymerase 1 (PARP1 inhibitor (DPQ-treated mice to compare them with the appropriate wild type controls. The repair kinetics data and the protein expression patterns observed indicate that the conventional NHEJ repair pathway is not available for elongated spermatids to repair the programmed and the IR-induced DSBs, reflecting the limited repair capacity of these cells. However, although elongated spermatids express the proteins of the alternative NHEJ, PARP1-inhibition had no effect on the repair kinetics after IR, suggesting that DNA damage may be passed onto sperm. Finally, our genetic mutant analysis suggests that an incomplete or defective meiotic recombinational repair of Spo11-induced DSBs may lead to a carry-over of the DSB damage or induce a delayed nuclear fragmentation during the sensitive programmed chromatin remodeling occurring in elongated spermatids.

  17. On the decrease of ultimate elongation of gum elastomer by irradiation

    International Nuclear Information System (INIS)

    Ito, Masayuki

    1986-01-01

    The reason why the ultimate elongation of gum elastomer decreases by irradiation was studied. The sample used is tetrafluoroethylenepropylene copolymer vulcanized which is a heat resistant elastomer. The sample was irradiated by a electron beam at room temperature. Cross-linking predominate in the operation. (Case 1) Scission predominant condition (Case 2) was given by irradiation of Co-60 γ ray at 100 deg C. Alternative irradiation of γ ray and electron beam under above condition can keep the original cross-linking density by the appropriate choice of each of the doses. (Case 3) The three cases mentioned above involve all of the cases of radiation induced aging of elastomers. Therefor, the following explanation for three cases shows the reason why the ultimate elongation of gum elastomer decreases by irradiation. Case 1. Cross-linking predominant condition. Ultimate elongation is proportional to -0.5 power of the dose. This fact can be explicable by the model of Buche, i.e. the breaking of a short chain causes another to break and that so on throughout the whole sample. Case 2. Chain scission predominant condition. Ultimate elongation increases by irradiation for a certain dose. This fact can understand by the model of Buche. But from a certain dose ultimate elongation does not increase. In the period the structure of the sample turned to be the same structure as the low molecular weight amorphose polymer vulcanized. Case 3. Rate of cross-linking and scission is the same. The average chain length does not chainge in the condition. But the distribution of chain length became wider and wider by irradiation. The increase of short chain result the decrease in ultimate elongation. (author)

  18. 4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells.

    Science.gov (United States)

    Suaud, Laurence; Miller, Katelyn; Panichelli, Ashley E; Randell, Rachel L; Marando, Catherine M; Rubenstein, Ronald C

    2011-12-30

    Sodium 4-phenylbutyrate (4PBA) corrects trafficking of ΔF508-CFTR in Cystic Fibrosis (CF) epithelia, which is hypothesized to, at least in part, result from increased expression of Hsp70 (stress-induced 70 kDa heat shock protein). To identify other 4PBA-regulated proteins that may promote correction of ΔF508 trafficking, we performed differential display RT-PCR on mRNA from IB3-1 CF bronchiolar epithelial cells treated for 0-24 h with 1 mM 4PBA. In this screen, a STAT-3 (signal transducer and activator of transcription-3)-interacting protein, StIP-1 that regulates STAT-3 activation had transiently increased expression. StIP-1 is identical to Elongator protein 2 (Elp2), a component of the Elongator complex that regulates RNA polymerase II. Previous studies have suggested that Elongator regulates Hsp70 mRNA transcription, and that the Hsp70 promoter contains functional STAT-3-binding sites. We therefore tested the hypothesis that 4PBA increases Hsp70 expression by an Elongator- and STAT-3-dependent mechanism. 4PBA treatment of IB3-1 CF bronchiolar epithelial cells caused transiently increased expression of Hsp70 protein, as well as Elp2 protein and mRNA. Elp2 depletion by transfection of small interfering RNAs, reduced both Elp2 and Hsp70 protein expression. 4PBA also caused transient activation of STAT-3, and increased abundance of nuclear proteins that bind to the STAT-3-responsive element of the Hsp70 promoter. Luciferase reporter assays demonstrated that both Elp2 overexpression and 4PBA increase Hsp70 promoter activity, while Elp2 depletion blocked the ability of 4PBA to stimulate Hsp70 promoter activity. Together, these data suggest that Elp2 and STAT-3 mediate, at least in part, the stimulation of Hsp70 expression by 4PBA.

  19. The accessory super-selective techniques in performing the transarterial embolization of intracranial dural arteriovenous fistulas

    International Nuclear Information System (INIS)

    Zhao Wenyuan; Liu Jianmin; Li Qiang; Fang Yibin; Xu Yi; Hong Bo; Huang Qinghai

    2010-01-01

    Objective: To evaluate the assistant techniques in performing transarterial embolization of intracranial dural arteriovenous fistulas (DAVF) when routine super-selective catheterization with microcatheter fails. Methods: Temporary balloon occlusion of the parent artery was adopted in 4 cases of anterior fossa DAVF and in one case of tentorial DAVF, and permanent occlusion of the distal main trunk with coils was carried out in one tentorial DAVF in order to help the super-selective catheterization. Results: The microcatheter was successfully advanced to, or near, the nidus with the help of these assistant techniques and all 6 cases were cured with single session. After the surgery no operation-related complications occurred. Conclusion: Our preliminary results indicate that the assistant techniques, including temporary balloon occlusion of the parent artery and permanent occlusion of the distal main trunk with coils, are a safe and effective method which can reliably help the successful performance of microcatheter catheterization, it can be safely used in complex cases when routine super-selective catheterization fails. (authors)

  20. Identification and super-resolution imaging of ligand-activated receptor dimers in live cells

    Science.gov (United States)

    Winckler, Pascale; Lartigue, Lydia; Giannone, Gregory; de Giorgi, Francesca; Ichas, François; Sibarita, Jean-Baptiste; Lounis, Brahim; Cognet, Laurent

    2013-08-01

    Molecular interactions are key to many chemical and biological processes like protein function. In many signaling processes they occur in sub-cellular areas displaying nanoscale organizations and involving molecular assemblies. The nanometric dimensions and the dynamic nature of the interactions make their investigations complex in live cells. While super-resolution fluorescence microscopies offer live-cell molecular imaging with sub-wavelength resolutions, they lack specificity for distinguishing interacting molecule populations. Here we combine super-resolution microscopy and single-molecule Förster Resonance Energy Transfer (FRET) to identify dimers of receptors induced by ligand binding and provide super-resolved images of their membrane distribution in live cells. By developing a two-color universal-Point-Accumulation-In-the-Nanoscale-Topography (uPAINT) method, dimers of epidermal growth factor receptors (EGFR) activated by EGF are studied at ultra-high densities, revealing preferential cell-edge sub-localization. This methodology which is specifically devoted to the study of molecules in interaction, may find other applications in biological systems where understanding of molecular organization is crucial.

  1. Heat treatment temperature influence on ASTM A890 GR 6A super duplex stainless steel microstructure

    International Nuclear Information System (INIS)

    Martins, Marcelo; Casteletti, Luiz Carlos

    2005-01-01

    Duplex and super duplex stainless steels are ferrous alloys with up to 26% chromium, 8% nickel, 5% molybdenum and 0.3% nitrogen, which are largely used in applications in media containing ions from the halogen family, mainly the chloride ion (Cl - ). The emergence of this material aimed at substituting Copper-Nickel alloys (Cupro-Nickel) that despite presenting good corrosion resistance, has mechanical properties quite inferior to steel properties. The metallurgy of duplex and super duplex stainless steel is complex due to high sensitiveness to sigma phase precipitation that becomes apparent, due to the temperatures they are exposed on cooling from solidification as well as from heat treatment processes. The objective of this study was to verify the influence of heat treating temperatures on the microstructure and hardness of ASTM A890/A890M Gr 6A super duplex stainless steel type. Microstructure control is of extreme importance for castings, as the chemical composition and cooling during solidification inevitably provide conditions for precipitation of sigma phase. Higher hardness in these materials is directly associated to high sigma phase concentration in the microstructure, precipitated in the ferrite/austenite interface. While heat treatment temperature during solution treatment increases, the sigma phase content in the microstructure decreases and consequently, the material hardness diminishes. When the sigma phase was completely dissolved by the heat treatment, the material hardness was influenced only due to ferrite and austenite contents in the microstructure

  2. A modified detector concept for SuperCDMS: The HiZIP and its charge performance

    Energy Technology Data Exchange (ETDEWEB)

    Page, Kedar Mohan [Queen' s U.

    2013-01-01

    SuperCDMS (Super Cryogenic Dark Matter Search) is a leading direct dark mat-ter search experiment which uses solid state detectors (Ge crystals) at milliKelvintemperatures to look for nuclear recoils caused by dark matter interactions in the de-tector. `Weakly Interacting Massive Particles' (WIMPs) are the most favoured darkmatter candidate particles. SuperCDMS, like many other direct dark matter searchexperiments, primarily looks for WIMPs. The measurement of both the ionizationand the lattice vibration (phonon) signals from an interaction in the detector allow itto discriminate against electron recoils which are the main source of background forWIMP detection.SuperCDMS currently operates about 9 kg of Ge detectors at the Soudan under-ground lab in northern Minnesota. In its next phase, SuperCDMS SNOLAB plansto use 100-200 kg of target mass (Ge) which would allow it to probe more of theinteresting and and as of yet unexplored parameter space for WIMPs predicted bytheoretical models. The SuperCDMS Queen's Test Facility is a detector test facilitywhich is intended to serve as detector testing and detector research and developmentpurposes for the SuperCDMS experiment.A modifed detector called the HiZIP (Half-iZIP), which is reduced in complex-ity in comparison to the currently used iZIP (interleaved Z-sensitive Ionization and Phonon mediated) detectors, is studied in this thesis. The HiZIP detector designalso serves to discriminate against background from multiple scatter events occurringclose to the surfaces in a single detector. Studies carried out to compare the surfaceevent leakage in the HiZIP detector using limited information from iZIP data takenat SuperCDMS test facility at UC Berkley produce a highly conservative upper limitof 5 out of 10,000 events at 90% condence level. This upper limit is the best amongmany different HiZIP congurations that were investigated and is comparable to theupper limit calculated for an HiZIP detector in the same way

  3. Contactless Measurement Of Rectilinearity Of An Elongated Object Based On The Example A Crane Rail

    Directory of Open Access Journals (Sweden)

    Ćmielewski Kazimierz

    2015-07-01

    Full Text Available The common aim of engineering surveys is to determine deviations from rectilinearity for elongated objects. We have developed a number of methods for measuring points that represent an elongated object. These are the constant straight (optical, laser, mechanical-string method, the trigonometric method, geometric levelling method, photogrammetric methods and terrestrial laser scanning. When taking these measurements, it is crucial to have a direct access to the survey points of the measured object. Factors impeding the measurements include: adverse lighting conditions, vibration, dust, refractory effects, lack of direct access to the survey points, etc.

  4. Towards an understanding of structure-function relationships of elongation factor Tu

    DEFF Research Database (Denmark)

    Wiborg, O; Andersen, C; Knudsen, Charlotte Rohde

    1994-01-01

    In light of the recently determined structure of elongation factor Tu, and taking into account chemical studies mapping functional sites, a number of residues have been selected for site-directed mutagenesis studies. Gly94, Gly126, His66, His118, Lys89 and Asp90 have each been point-mutated. Prel......In light of the recently determined structure of elongation factor Tu, and taking into account chemical studies mapping functional sites, a number of residues have been selected for site-directed mutagenesis studies. Gly94, Gly126, His66, His118, Lys89 and Asp90 have each been point...

  5. Stereotypical reaching movements of the octopus involve both bend propagation and arm elongation.

    Science.gov (United States)

    Hanassy, S; Botvinnik, A; Flash, T; Hochner, B

    2015-05-13

    The bend propagation involved in the stereotypical reaching movement of the octopus arm has been extensively studied. While these studies have analyzed the kinematics of bend propagation along the arm during its extension, possible length changes have been ignored. Here, the elongation profiles of the reaching movements of Octopus vulgaris were assessed using three-dimensional reconstructions. The analysis revealed that, in addition to bend propagation, arm extension movements involve elongation of the proximal part of the arm, i.e., the section from the base of the arm to the propagating bend. The elongations are quite substantial and highly variable, ranging from an average strain along the arm of -0.12 (i.e. shortening) up to 1.8 at the end of the movement (0.57 ± 0.41, n = 64 movements, four animals). Less variability was discovered in an additional set of experiments on reaching movements (0.64 ± 0.28, n = 30 movements, two animals), where target and octopus positions were kept more stationary. Visual observation and subsequent kinematic analysis suggest that the reaching movements can be broadly segregated into two groups. The first group involves bend propagation beginning at the base of the arm and propagating towards the arm tip. In the second, the bend is formed or present more distally and reaching is achieved mainly by elongation and straightening of the segment proximal to the bend. Only in the second type of movements is elongation significantly positively correlated with the distance of the bend from the target. We suggest that reaching towards a target is generated by a combination of both propagation of a bend along the arm and arm elongation. These two motor primitives may be combined to create a broad spectrum of reaching movements. The dynamical model, which recapitulates the biomechanics of the octopus muscular hydrostatic arm, suggests that achieving the observed elongation requires an extremely low ratio of longitudinal to transverse muscle

  6. Determination of baryon-baryon elastic scattering phase shift from finite volume spectra in elongated boxes

    Science.gov (United States)

    Li, Ning; Wu, Ya-Jie; Liu, Zhan-Wei

    2018-01-01

    The relations between the baryon-baryon elastic scattering phase shifts and the two-particle energy spectrum in the elongated box are established. We studied the cases with both the periodic boundary condition and twisted boundary condition in the center of mass frame. The framework is also extended to the system of nonzero total momentum with periodic boundary condition in the moving frame. Moreover, we discussed the sensitivity functions σ (q ) that represent the sensitivity of higher scattering phases. Our analytical results will be helpful to extract the baryon-baryon elastic scattering phase shifts in the continuum from lattice QCD data by using elongated boxes.

  7. Positive grid corrosion elongation analysis using CAE with corrosion deformation transformed into thermal phenomenon

    Science.gov (United States)

    Mukaitani, Ichiroh; Hayashi, Koji; Shimoura, Ichiro; Takemasa, Arihiko; Takahashi, Isamu; Tsubakino, Harushige

    Valve-regulated lead-acid (VRLA) batteries have been commercially available for more than 20 years and have been enthusiastically embraced by users of uninterruptible power supplies (UPS) because of the anticipated reduction in installation and operating costs, smaller footprint and fewer environmental concerns. In Japan, communication networks are demanding reduced costs and longer life from their batteries. Among the factors limiting the life of VRLA batteries, the corrosion of positive grid material has been proven to cause elongation of the plates, loss of electrical contact and shorter lifetime. The content of Sn is also a key factor and addition of Sn in the grid alloy results in better performance in creep resistance, tensile strength and corrosion resistance [R. David Prenagaman, The Battery Man, vol. 39, September 1997, p. 16. I. Mukaitani, T. Sakamoto, T. Kikuoka, Y. Yamaguchi, H. Tsubakino, Proceedings of the 40th Battery Symposium in Japan, 1999, p. 99]. A key point is what the ratio of Sn to Ca should be, since too much Sn may lead to even worse elongation of the plates [I. Mukaitani, T. Sakamoto, T. Kikuoka, Y. Yamaguchi, H. Tsubakino, Proceedings of the 40th Battery Symposium in Japan, 1999, p. 99]. We have determined that microstructure control with a composition of lead-calcium-tin (Pb-Ca-Sn) alloy is optimal for better performance of the plates [I. Mukaitani, T. Sakamoto, T. Kikuoka, Y. Yamaguchi, H. Tsubakino, Proceedings of the 40th Battery Symposium in Japan, 1999, p. 99]. We developed a "simulation of current collector corrosion elongation" which is a technique of estimating corrosion elongation from the current collector design [I. Mukaitani, K. Hayashi, I. Shimoura, H. Takabayashi, M. Terada, A. Takemasa, I. Takahashi, K. Okamoto, Proceedings of the 44th Battery Symposium in Japan, 2003, p. 652]. Corrosion elongation occurs as the corrosion material layer grows out of the current collector metal. We resolved this problem using generally CAD

  8. Pioneering SUPER - Small Unit Passively-safe Enclosed Reactor - 15559

    International Nuclear Information System (INIS)

    Bhownik, P.K.; Gairola, A.; Shamim, J.A.; Suh, K.Y.; Suh, K.S.

    2015-01-01

    This paper presents the basic features of the Small Unit Passively-safe Enclosed Reactor abbreviated as SUPER, a new reactor system that has been designed and proposed at the Seoul National University's Department of Energy Systems Engineering. SUPER is a small modular reactor system or SMR that is cooled by sub-cooled as well as supercritical water. As a new member of SMRs, SUPER is a small-scale nuclear plant that is designed to be factory-manufactured and shipped as modules to be assembled at a site. The concept offers promising answers to many questions about nuclear power including proliferation resistance, waste management, safety, and startup costs. SUPER is a customized paradigm of a supercritical water reactor or SCWR, a type sharing commonalities with the current fleet of light water reactors, or LWRs. SUPER has evolved from the System-integrated Modular Advance Reactor, or SMART, being developed at the Korea Atomic Energy Research Institute, or KAERI. SUPER enhanced the safety features for robustness, design/equipment simplification for natural convection, multi-purpose application for co-generation flexibilities, suitable for isolated or small electrical grids, just-in-time capacity addition, short construction time, and last, but not least, lower capital cost per unit. The primary objectives of SUPER is to develop the conceptual design for a safe and economic small, natural circulation SCWR, to address the economic and safety attributes of the concept, and to demonstrate its technical feasibilities. (authors)

  9. Super-leadership and work enjoyment: direct and moderated influences.

    Science.gov (United States)

    Müller, Günter F; Georgianna, Sibylle; Schermelleh-Engel, Karin; Roth, Anne C; Schreiber, Walter A; Sauerland, Martin; Muessigmann, Michael J; Jilg, Franziska

    2013-12-01

    Super-leadership is part of an approach called 'empowering leadership.' Within this approach, super-leadership is assumed to enable subordinates to lead themselves. The current study examined correlates of super-leadership. A questionnaire measuring two dimensions of super-leadership was used to analyze relationships between super-leadership and subordinates' work enjoyment, i.e., job satisfaction, subjective well-being, and emotional organizational commitment. In addition, moderating effects of the organizational context, i.e., organizational decentralization, on the relationships between super-leadership and work enjoyment were explored. 198 German employees from different occupations participated in the study. Latent moderator structural equation analysis revealed that the two factors of super-leadership, "coaching and communicative support" and "facilitation of personal autonomy and responsibility," had direct positive effects on subordinates' work enjoyment. Organizational decentralization moderated the effect of "coaching and communicative support" on work enjoyment but not the relations involving "facilitation of personal autonomy and responsibility." Conclusions for further research and practical applications were discussed.

  10. Learning-based compressed sensing for infrared image super resolution

    Science.gov (United States)

    Zhao, Yao; Sui, Xiubao; Chen, Qian; Wu, Shaochi

    2016-05-01

    This paper presents an infrared image super-resolution method based on compressed sensing (CS). First, the reconstruction model under the CS framework is established and a Toeplitz matrix is selected as the sensing matrix. Compared with traditional learning-based methods, the proposed method uses a set of sub-dictionaries instead of two coupled dictionaries to recover high resolution (HR) images. And Toeplitz sensing matrix allows the proposed method time-efficient. Second, all training samples are divided into several feature spaces by using the proposed adaptive k-means classification method, which is more accurate than the standard k-means method. On the basis of this approach, a complex nonlinear mapping from the HR space to low resolution (LR) space can be converted into several compact linear mappings. Finally, the relationships between HR and LR image patches can be obtained by multi-sub-dictionaries and HR infrared images are reconstructed by the input LR images and multi-sub-dictionaries. The experimental results show that the proposed method is quantitatively and qualitatively more effective than other state-of-the-art methods.

  11. Selective laser melting of Inconel super alloy-a review

    Science.gov (United States)

    Karia, M. C.; Popat, M. A.; Sangani, K. B.

    2017-07-01

    Additive manufacturing is a relatively young technology that uses the principle of layer by layer addition of material in solid, liquid or powder form to develop a component or product. The quality of additive manufactured part is one of the challenges to be addressed. Researchers are continuously working at various levels of additive manufacturing technologies. One of the significant powder bed processes for met als is Selective Laser Melting (SLM). Laser based processes are finding more attention of researchers and industrial world. The potential of this technique is yet to be fully explored. Due to very high strength and creep resistance Inconel is extensively used nickel based super alloy for manufacturing components for aerospace, automobile and nuclear industries. Due to law content of Aluminum and Titanium, it exhibits good fabricability too. Therefore the alloy is ideally suitable for selective laser melting to manufacture intricate components with high strength requirements. The selection of suitable process for manufacturing for a specific component depends on geometrical complexity, production quantity, and cost and required strength. There are numerous researchers working on various aspects like metallurgical and micro structural investigations and mechanical properties, geometrical accuracy, effects of process parameters and its optimization and mathematical modeling etc. The present paper represents a comprehensive overview of selective laser melting process for Inconel group of alloys.

  12. Super-resolution for a point source using positive refraction

    Science.gov (United States)

    Miñano, Juan C.; Benítez, Pablo; González, Juan C.; Grabovičkić, Dejan; Ahmadpanahi, Hamed

    Leonhardt demonstrated (2009) that the 2D Maxwell Fish Eye lens (MFE) can focus perfectly 2D Helmholtz waves of arbitrary frequency, i.e., it can transport perfectly an outward (monopole) 2D Helmholtz wave field, generated by a point source, towards a receptor called "perfect drain" (PD) located at the corresponding MFE image point. The PD has the property of absorbing the complete radiation without radiation or scattering and it has been claimed as necessary to obtain super-resolution (SR) in the MFE. However, a prototype using a "drain" different from the PD has shown λ/5 resolution for microwave frequencies (Ma et al, 2010). Recently, the SR properties of a device equivalent to the MFE, called the Spherical Geodesic Waveguide (SGW) (Miñano et al, 2012) have been analyzed. The reported results show resolution up to λ /3000, for the SGW loaded with the perfect drain, and up to λ /500 for the SGW without perfect drain. The perfect drain was realized as a coaxial probe loaded with properly calculated impedance. The SGW provides SR only in a narrow band of frequencies close to the resonance Schumann frequencies. Here we analyze the SGW loaded with a small "perfect drain region" (González et al, 2011). This drain is designed as a region made of a material with complex permittivity. The comparative results show that there is no significant difference in the SR properties for both perfect drain designs.

  13. SuperSpike: Supervised Learning in Multilayer Spiking Neural Networks.

    Science.gov (United States)

    Zenke, Friedemann; Ganguli, Surya

    2018-04-13

    A vast majority of computation in the brain is performed by spiking neural networks. Despite the ubiquity of such spiking, we currently lack an understanding of how biological spiking neural circuits learn and compute in vivo, as well as how we can instantiate such capabilities in artificial spiking circuits in silico. Here we revisit the problem of supervised learning in temporally coding multilayer spiking neural networks. First, by using a surrogate gradient approach, we derive SuperSpike, a nonlinear voltage-based three-factor learning rule capable of training multilayer networks of deterministic integrate-and-fire neurons to perform nonlinear computations on spatiotemporal spike patterns. Second, inspired by recent results on feedback alignment, we compare the performance of our learning rule under different credit assignment strategies for propagating output errors to hidden units. Specifically, we test uniform, symmetric, and random feedback, finding that simpler tasks can be solved with any type of feedback, while more complex tasks require symmetric feedback. In summary, our results open the door to obtaining a better scientific understanding of learning and computation in spiking neural networks by advancing our ability to train them to solve nonlinear problems involving transformations between different spatiotemporal spike time patterns.

  14. Study on surface defects in milling Inconel 718 super alloy

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Liu; Chengzu, Ren; Guofeng, Wang; Yinwei, Yang; Lu, Zhang [Tianjin University, Tianjin (China)

    2015-04-15

    Nickel-based alloys have been extensively used as critical components in aerospace industry, especially in the key section of aero engine. In general, these sections are manufactured by milling process because most of them have complex forms. However, surface defects appear frequently in milling due to periodic impact force, which leads to the deterioration of the fatigue life. We conducted milling experiments under different cutting conditions and found that four kinds of defects, i.e., tear, cavity, build up edge (BUE) and groove, commonly appear on the machined surface. Based on the observed results, the morphology and generation regime of these defects are analyzed and the carbide particle cracking is discussed to explain the appearance of the nickel alloy defects. To study the effect of the cutting parameters on the severity of these surface defects, two qualitative indicators, which are named as average number of the defects per field and average area ratio of the defects per field, are presented and the influence laws are summarized based on the results correspondingly. This study is helpful for understanding the generation mechanism of the surface defects during milling process of nickel based super alloy.

  15. Application of spectroscopy and super-resolution microscopy: Excited state

    Energy Technology Data Exchange (ETDEWEB)

    Bhattacharjee, Ujjal [Iowa State Univ., Ames, IA (United States)

    2016-02-19

    Photophysics of inorganic materials and organic molecules in complex systems have been extensively studied with absorption and emission spectroscopy.1-4 Steady-state and time-resolved fluorescence studies are commonly carried out to characterize excited-state properties of fluorophores. Although steady-state fluorescence measurements are widely used for analytical applications, time-resolved fluorescence measurements provide more detailed information about excited-state properties and the environment in the vicinity of the fluorophore. Many photophysical processes, such as photoinduced electron transfer (PET), rotational reorientation, solvent relaxation, and energy transfer, occur on a nanosecond (10-9 s) timescale, thus affecting the lifetime of the fluorophores. Moreover, time-resolved microscopy methods, such as lifetimeimaging, combine the benefits of the microscopic measurement and information-rich, timeresolved data. Thus, time-resolved fluorescence spectroscopy combined with microscopy can be used to quantify these processes and to obtain a deeper understanding of the chemical surroundings of the fluorophore in a small area under investigation. This thesis discusses various photophysical and super-resolution microscopic studies of organic and inorganic materials, which have been outlined below.

  16. Label-free super sandwich electrogenerated chemiluminescence biosensor for the determination of the HIV gene

    International Nuclear Information System (INIS)

    Ruan, Sanpeng; Li, Zhejian; Qi, Honglan; Gao, Qiang; Zhang, Chengxiao

    2014-01-01

    We describe a highly sensitive electrochemiluminescence (ECL) based method for the determination of the human immunodeficiency virus-1 (HIV-1) gene. A long-range self-assembled double strand DNA (ds-DNA) is used as a carrier, and the ruthenium complex Ru(phen) 3 2+ as an ECL indicator for signal amplification. The thiolated ss-DNA serving as a capture probe is firstly self-assembled on the surface of a gold electrode. After the target HIV-1 gene is completely hybridized with the capture probe, two previously hybridized auxiliary probes are hybridized with the target HIV-1 gene to form long-range super sandwich ds-DNA polymers on the surface of the electrode. Finally, the ECL indicator is intercalated into the super sandwich ds-DNA grooves. This results in a strongly increased ECL in tripropylamine solution because a large fraction of the intercalator is intercalated into super sandwich ds-DNA. The results showed that the increased ECL intensity is directly related to the logarithm of the concentration of the HIV-1 gene in the range from 0.1 pM to 0.1 nM, with a detection limit of 0.022 pM and using only 10 μL of analyte samples. The method can effectively discriminate target HIV-1 gene (a perfectly matched ss-DNA) from a 2-base mismatched ss-DNA. This work demonstrates that the high sensitivity and selectivity of an ECL DNA biosensor can be largely improved by using super sandwich ds-DNA along with ECL indicators. (author)

  17. Chebyshev super spectral viscosity method for water hammer analysis

    Directory of Open Access Journals (Sweden)

    Hongyu Chen

    2013-09-01

    Full Text Available In this paper, a new fast and efficient algorithm, Chebyshev super spectral viscosity (SSV method, is introduced to solve the water hammer equations. Compared with standard spectral method, the method's advantage essentially consists in adding a super spectral viscosity to the equations for the high wave numbers of the numerical solution. It can stabilize the numerical oscillation (Gibbs phenomenon and improve the computational efficiency while discontinuities appear in the solution. Results obtained from the Chebyshev super spectral viscosity method exhibit greater consistency with conventional water hammer calculations. It shows that this new numerical method offers an alternative way to investigate the behavior of the water hammer in propellant pipelines.

  18. Superfield realizations of N=2 super-W3

    International Nuclear Information System (INIS)

    Ivanov, E.; Krivonos, S.

    1992-04-01

    We present a manifestly N=2 supersymmetric formulation of N=2 super-W 3 algebra (its classical version) in terms of the spin 1 and spin 2 supercurrents. Two closely related types of the Feigin-Fuchs representation for these supercurrents are found: via two chiral spin 1/2 superfields generating N=2 extended U(1) Kac-Moody algebras and via two free chiral spin 0 superfields. We also construct a one-parameter family of N=2 super Boussinesq equations for which N=2 super-W 3 provides the second Hamiltonian structure. (author). 17 refs

  19. Arbitrarily high super-resolving phase measurements at telecommunication wavelengths

    International Nuclear Information System (INIS)

    Kothe, Christian; Bjoerk, Gunnar; Bourennane, Mohamed

    2010-01-01

    We present two experiments that achieve phase super-resolution at telecommunication wavelengths. One of the experiments is realized in the space domain and the other is realized in the time domain. Both experiments show high visibility and are performed with standard lasers and single-photon detectors. The first experiment uses six-photon coincidences, whereas the latter experiment needs no coincidence measurements, is easy to perform, and achieves, in principle, arbitrarily high phase super-resolution. Here, we demonstrate a 30-fold increase of the resolution. We stress that neither entanglement nor joint detection is needed in these experiments, which demonstrates that neither is necessary to achieve phase super-resolution.

  20. On some classes of super quasi-Einstein manifolds

    International Nuclear Information System (INIS)

    Ozguer, Cihan

    2009-01-01

    Quasi-Einstein and generalized quasi-Einstein manifolds are the generalizations of Einstein manifolds. In this study, we consider a super quasi-Einstein manifold, which is another generalization of an Einstein manifold. We find the curvature characterizations of a Ricci-pseudosymmetric and a quasi-conformally flat super quasi-Einstein manifolds. We also consider the condition C ∼ .S=0 on a super quasi-Einstein manifold, where C ∼ and S denote the quasi-conformal curvature tensor and Ricci tensor of the manifold, respectively.