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Sample records for sung wook shim

  1. Analisis Intensitas Pencahayaan Dan Reflektan Di Lingkungan Kerja Terhadap Kelelahan Mata Pada Tenaga Kerja Industri Bulu Mata Palsu Di PT. Sung Shim International Purbalingga.

    Directory of Open Access Journals (Sweden)

    Feriyandi Feriyandi

    2015-12-01

    Full Text Available ABSTRACT Background : There are approximately 15,000 workers in several spurious eyelash industries in Purbalingga Regency. Since objects being observed are very fine and the tasks need high accuracy, good lighting is therefore highly required. Poor lighting can lead to visual and mental fatigue, stiffness around the eyes, eye damage and the increasing of work accidents. Sufficient intensity and good management of lighting will result a comfort environment in accordance  to achieve a safe  work environment. Method : This research was conducted as  observational study with a cross sectional approach  for 45 samples of workers. Sampling was carried out by using of systematic random sampling. Data of light intensity and reflectance were collected by measurement of light using Lux Meter and assessment of visual fatigue by using Retention Timer. Other data were collected by interviewing workers with age limitation up to 33 years old. Chi Square Test was used to analyze the data of light intensity and reflectance, work years, age, work period, distance of light to object, distance of eyes to object, relative humidity and temperature, and the correlation with the rise of visual fatigue. Result : Light intensity in the knitting section was between 301.5 – 576.7 lux with reflectance of 43.1%-89.6%. Thirty wokers (66.7% suffered from mild visual fatigue and fifteen wokers, suffered (33.3% from moderate visual fatigue. Light intensity had  an influence and significant relationship  to the occurring of visual fatigue among workers in the industry of spurious eyelash of  PT. Sung Shim International  (p < 0,05 with  Odd ratio = 10.246 (95% CI : 1.147 - 91.498.  Probability of light intensity factor to cause visual fatigue measured by a regression logistic model  was  82.9% . It was caused by  poor lighting (light intensities were measured  below 500 lux while 17.1%  was caused by  other factors. Conclusion : Most of the spurious eyelash

  2. 有关韩国与中国大学生使用社交媒体的动机对社交媒体广告使用意向的影响之研究%A study on the effects and motives of college students using social media on advertisement usage between Korea and ChinaShim Sung Wook

    Institute of Scientific and Technical Information of China (English)

    沈星旭

    2011-01-01

    本文主要是为了研究韩国与中国的大学生使用社交媒体( Social Media)的动机,以及与广告使用动机进行比较并找出其差异.为此本文采用媒体的使用与满足理论(use and gratification theory),找出使用社交媒体的动机,并分析了这些动机对社交媒体广告的使用意向起到何种影响.分析结果显示,第一、韩国与中国的大学生使用社交媒体都是出于实用性动机;第二、在两国使用社交媒体的动机来看,韩国只有在使用值得信赖的广告方面起到积极影响,而中国在信息的可信赖度、转换心情、个人实用性等使用广告的三个动机上都起到了影响.本文的研究结果表明,在使用社交媒体广告时,韩国消费者的“使用网络信息与内容”、“网络搜索”、“追求娱乐”等使用动机起到了积极效果,而社交媒体广告的可信赖度得到满足最为重要;而中国消费者的“网络搜索”对使用“值得信赖的”广告的动机时起到了积极影响,“社会联系”、“在意别人对自己的评价”等选项则是为了“转换心情”使用广告起到了积极影响,另外“社会联系”还对“个人实用性”广告使用动机起到了影响.

  3. Dynamic B0 shimming at 7 T.

    Science.gov (United States)

    Sengupta, Saikat; Welch, E Brian; Zhao, Yansong; Foxall, David; Starewicz, Piotr; Anderson, Adam W; Gore, John C; Avison, Malcolm J

    2011-05-01

    Dynamic slice-wise shimming improves B0 field homogeneity by updating shim coil currents for every slice in a multislice acquisition, producing better field homogeneity over a volume than can be obtained by a single static global shim. The first aim of this work was to evaluate the performance of slice-wise field-map-based second-order dynamic shimming in a human high-field 7 T clinical scanner vis-à-vis image based second order static global shimming. Another goal was to characterize eddy currents induced by second and third order shim switching. A final aim was to compare global and dynamic shimming through shim orders to elucidate the relative benefits of going to higher orders and to dynamic shim updating from a static shimming regime. An external hardware module was used to store and dynamically update slice-optimized shim values during multislice data acquisition. High-bandwidth multislice gradient echo scans with B0 field mapping and low-bandwidth single-shot echo planar scans were performed on phantoms and humans using second-order dynamic and static global shims. For the measurement of second and third order shim induced eddy currents, step response temporal phase changes of individual shims were measured and fit to shim harmonics spatially and to multiexponential decay functions temporally. Finally, an order-wise field-map-based comparison was performed with first, second and third order global static shimming, first and second order dynamic shimming, as well as combined second or third order global and first order dynamic shim. Dynamic shimming considerably improved B0 homogeneity compared to static global shimming both in phantoms and in human subjects, reducing image distortion and signal dropout. The unshielded second and third order shims generated strong B0 and self and cross-term eddy fields, with multiple time constants ranging from milliseconds to seconds. Field homogeneity improved with increasing order of shim, with dynamic shimming performing

  4. Induction shimming: A new shimming concept for superconductive undulators

    Directory of Open Access Journals (Sweden)

    D. Wollmann

    2008-10-01

    Full Text Available Undulators are the most advanced sources for the generation of synchrotron radiation. The photons generated by a single electron add up coherently along the electron trajectory. In order to do so, the oscillatory motion of the electron has to be in phase with the emitted photons along the whole undulator. Small magnetic errors can cause unwanted destructive interferences. In standard permanent magnet undulators, the magnetic errors are reduced by applying shimming techniques. Superconductive undulators have higher magnetic fields than permanent magnet undulators but shimming is more complex. In this paper it is shown that coupled superconductive loops installed along the surface of the superconductive undulator coil can significantly reduce the destructive effect of the field errors. This new idea might allow the building of undulators with a superior field quality.

  5. Installation of Shimming Bars for CYCIAE-100

    Institute of Scientific and Technical Information of China (English)

    LV; Yin-long; WANG; Zhen-hui; ZHONG; Jun-qing; LIU; Geng-shou

    2012-01-01

    <正>The 100 MeV high intensity proton cyclotron, CYCIAE-100, is the most critical equipment of the BRIF project at CIAE. The shimming bars are used to get the isochronous magnetic field. In the process of magnetic mapping and shimming, the bars should be repeated the installed and disassembly for about 10 times. Each time the installation precision must be ensured. The bars installation schedule and quality are directly related to the BRIF project progress.

  6. Multipole shimming of permanent magnets using harmonic corrector rings.

    Science.gov (United States)

    Jachmann, R C; Trease, D R; Bouchard, L-S; Sakellariou, D; Martin, R W; Schlueter, R D; Budinger, T F; Pines, A

    2007-03-01

    Shimming systems are required to provide sufficient field homogeneity for high resolution nuclear magnetic resonance (NMR). In certain specialized applications, such as rotating-field NMR and mobile ex situ NMR, permanent magnet-based shimming systems can provide considerable advantages. We present a simple two-dimensional shimming method based on harmonic corrector rings which can provide arbitrary multipole order shimming corrections. Results demonstrate, for example, that quadrupolar order shimming improves the linewidth by up to an order of magnitude. An additional order of magnitude reduction is in principle achievable by utilizing this shimming method for z-gradient correction and higher order xy gradients.

  7. Integrated RF/shim coil array for parallel reception and localized B0 shimming in the human brain.

    Science.gov (United States)

    Truong, Trong-Kha; Darnell, Dean; Song, Allen W

    2014-12-01

    The purpose of this work was to develop a novel integrated radiofrequency and shim (RF/shim) coil array that can perform parallel reception and localized B0 shimming in the human brain with the same coils, thereby maximizing both the signal-to-noise ratio and shimming efficiency. A 32-channel receive-only head coil array was modified to enable both RF currents (for signal reception) and direct currents (for B0 shimming) to flow in individual coil elements. Its in vivo performance was assessed in the frontal brain region, which is affected by large susceptibility-induced B0 inhomogeneities. The coil modifications did not reduce their quality factor or signal-to-noise ratio. Axial B0 maps and echo-planar images acquired in vivo with direct currents optimized to shim specific slices showed substantially reduced B0 inhomogeneities and image distortions in the frontal brain region. The B0 root-mean-square error in the anterior half of the brain was reduced by 60.3% as compared to that obtained with second-order spherical harmonic shimming. These results demonstrate that the integrated RF/shim coil array can perform parallel reception and localized B0 shimming in the human brain and provide a much more effective shimming than conventional spherical harmonic shimming alone, without taking up additional space in the magnet bore and without compromising the signal-to-noise ratio or shimming performance.

  8. AA, shims and washers on quadrupole ends

    CERN Multimedia

    CERN PhotoLab

    1981-01-01

    Due to the fact that much of the field of the quadrupoles was outside the iron (in particular with the wide quadrupoles) and that thus the fields of quadrupoles and bending magnets interacted, the lattice properties of the AA could not be predicted with the required accuracy. After a first running period in 1980, during which detailed measurements were made with proton test beams, corrections to the quadrupoles were made in 1981, in the form of laminated shims at the ends of the poles, and with steel washers. With the latter ones, further refinements were made in an iterative procedure with measurements on the circulating beam. This eventually resulted, amongst other things, in a very low chromaticity, with the Q-values being constant to within +- 0.001 over the total momentum range of 6 %. Here we see the shims and washers on a narrow qudrupole (QFN, QDN). See also 8103203, 8103204, 8103205, 8103206.

  9. SHIMS -- A Spatial Heterodyne Interferometer for Methane Sounding Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project develops the Spatial Heterodyne Interferometer for Methane Sounding (SHIMS), a lightweight, compact, robust spectrometer system for remote sensing of...

  10. Perception of Sung Speech in Bimodal Cochlear Implant Users

    Science.gov (United States)

    Galvin, John J.; Fu, Qian-Jie

    2016-01-01

    Combined use of a hearing aid (HA) and cochlear implant (CI) has been shown to improve CI users’ speech and music performance. However, different hearing devices, test stimuli, and listening tasks may interact and obscure bimodal benefits. In this study, speech and music perception were measured in bimodal listeners for CI-only, HA-only, and CI + HA conditions, using the Sung Speech Corpus, a database of monosyllabic words produced at different fundamental frequencies. Sentence recognition was measured using sung speech in which pitch was held constant or varied across words, as well as for spoken speech. Melodic contour identification (MCI) was measured using sung speech in which the words were held constant or varied across notes. Results showed that sentence recognition was poorer with sung speech relative to spoken, with little difference between sung speech with a constant or variable pitch; mean performance was better with CI-only relative to HA-only, and best with CI + HA. MCI performance was better with constant words versus variable words; mean performance was better with HA-only than with CI-only and was best with CI + HA. Relative to CI-only, a strong bimodal benefit was observed for speech and music perception. Relative to the better ear, bimodal benefits remained strong for sentence recognition but were marginal for MCI. While variations in pitch and timbre may negatively affect CI users’ speech and music perception, bimodal listening may partially compensate for these deficits. PMID:27837051

  11. Effect of Shim Arm Depletion in the NBSR

    Energy Technology Data Exchange (ETDEWEB)

    Hanson A. H.; Brown N.; Diamond, D.J.

    2013-02-22

    The cadmium shim arms in the NBSR undergo burnup during reactor operation and hence, require periodic replacement. Presently, the shim arms are replaced after every 25 cycles to guarantee they can maintain sufficient shutdown margin. Two prior reports document the expected change in the 113Cd distribution because of the shim arm depletion. One set of calculations was for the present high-enriched uranium fuel and the other for the low-enriched uranium fuel when it was in the COMP7 configuration (7 inch fuel length vs. the present 11 inch length). The depleted 113Cd distributions calculated for these cores were applied to the current design for an equilibrium low-enriched uranium core. This report details the predicted effects, if any, of shim arm depletion on the shim arm worth, the shutdown margin, power distributions and kinetics parameters.

  12. A Comprehensive Trainable Error Model for Sung Music Queries

    CERN Document Server

    Birmingham, W P; 10.1613/jair.1334

    2011-01-01

    We propose a model for errors in sung queries, a variant of the hidden Markov model (HMM). This is a solution to the problem of identifying the degree of similarity between a (typically error-laden) sung query and a potential target in a database of musical works, an important problem in the field of music information retrieval. Similarity metrics are a critical component of query-by-humming (QBH) applications which search audio and multimedia databases for strong matches to oral queries. Our model comprehensively expresses the types of error or variation between target and query: cumulative and non-cumulative local errors, transposition, tempo and tempo changes, insertions, deletions and modulation. The model is not only expressive, but automatically trainable, or able to learn and generalize from query examples. We present results of simulations, designed to assess the discriminatory potential of the model, and tests with real sung queries, to demonstrate relevance to real-world applications.

  13. Melodic contour identification and sentence recognition using sung speech.

    Science.gov (United States)

    Crew, Joseph D; Galvin, John J; Fu, Qian-Jie

    2015-09-01

    For bimodal cochlear implant users, acoustic and electric hearing has been shown to contribute differently to speech and music perception. However, differences in test paradigms and stimuli in speech and music testing can make it difficult to assess the relative contributions of each device. To address these concerns, the Sung Speech Corpus (SSC) was created. The SSC contains 50 monosyllable words sung over an octave range and can be used to test both speech and music perception using the same stimuli. Here SSC data are presented with normal hearing listeners and any advantage of musicianship is examined.

  14. Hemispheric specialization for linguistic processing of sung speech.

    Science.gov (United States)

    Yelle, Serena K; Grimshaw, Gina M

    2009-02-01

    The two hemispheres of the brain play complementary roles in song perception, with the left hemisphere specialized for processing the linguistic aspects of song and the right hemisphere specialized for the processing of melody. However, very little is known about how language and melody interact. The present study tested the hypothesis that right hemisphere linguistic processing would be facilitated by the presence of melody. In a dichotic listening paradigm, participants (8 men, 43 women) performed a linguistic task while listening to spoken or sung speech. Contrary to the hypothesis, left hemisphere specialization for linguistic processing was identical whether the sentences were spoken or sung.

  15. Magnetic field shimming of a permanent magnet using a combination of pieces of permanent magnets and a single-channel shim coil for skeletal age assessment of children.

    Science.gov (United States)

    Terada, Y; Kono, S; Ishizawa, K; Inamura, S; Uchiumi, T; Tamada, D; Kose, K

    2013-05-01

    We adopted a combination of pieces of permanent magnets and a single-channel (SC) shim coil to shim the magnetic field in a magnetic resonance imaging system dedicated for skeletal age assessment of children. The target magnet was a 0.3-T open and compact permanent magnet tailored to the hand imaging of young children. The homogeneity of the magnetic field was first improved by shimming using pieces of permanent magnets. The residual local inhomogeneity was then compensated for by shimming using the SC shim coil. The effectiveness of the shimming was measured by imaging the left hands of human subjects and evaluating the image quality. The magnetic resonance images for the child subject clearly visualized anatomical structures of all bones necessary for skeletal age assessment, demonstrating the usefulness of combined shimming.

  16. [Mechanical Shimming Method and Implementation for Permanent Magnet of MRI System].

    Science.gov (United States)

    Xue, Tingqiang; Chen, Jinjun

    2015-03-01

    A mechanical shimming method and device for permanent magnet of MRI system has been developed to meet its stringent homogeneity requirement without time-consuming passive shimming on site, installation and adjustment efficiency has been increased.

  17. A SQP optimization method for shimming a permanent MRI magnet

    Institute of Scientific and Technical Information of China (English)

    Zhe Jin; Xing Tang; Bin Meng; Donglin Zu; Weimin Wang

    2009-01-01

    Based on the sequential quadratic programming (SQP) method, a new approach is presented in this paper to gain a uniform magnetic field for a permanent MRI magnet with biplanar poles. First, the adopted shimming piece is modeled as a magnetic dipole moment to calculate its effect on the background field over the imaging region of interest. Then, the SQP method is utilized to determine the ideal solution for the shimming equation. Finally, the ideal solution is discrete, and the quantization error control technique is used for special cases. This new method helps to reduce the inhomogeneity from 1234.5 ppm to 21.4 ppm over a 36 cm diameter spherical volume (DSV), within hours in practical shimming work.

  18. Beam spoiling a reflector antenna with conducting shim.

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin Walter

    2012-12-01

    A horn-fed dish reflector antenna has characteristics including beam pattern that are a function of its mechanical form. The beam pattern can be altered by changing the mechanical configuration of the antenna. One way to do this is with a reflecting insert or shim added to the face of the original dish.

  19. Polar-drive experiments with shimmed targets on OMEGA

    Science.gov (United States)

    Marshall, F. J.; Radha, P. B.; Bonino, M. J.; Delettrez, J. A.; Epstein, R.; Skupsky, S.; Giraldez, E.

    2012-10-01

    Polar-drive experiments are being performed on OMEGA in preparation for future ignition attempts using the same method on the National Ignition Facility. This work presents results from a series of experiments employing shimmed shells whose shape (thinner at the target equator) is used to further compensate for the oblique illumination present in the polar-drive beam configuration. Implosion experiments were performed with multiple-picket laser pulses from 40 OMEGA beams driving gas-filled, shimmed shells. The implosions were diagnosed with x-ray backlighting, fusion yield, and reaction particle spectra from which the implosion symmetry, areal density, and core conditions are inferred. The compressed shell shape determined from framed x-ray radiography is compared to that predicted by the 2-D hydrodynamics code DRACO. The benefits of using a shimmed target for polar-drive implosions are less oblique illumination, better low-mode implosion symmetry, and are clearly demonstrated by these experiments. This work was supported by the U.S. Department of Energy Office of Inertial Confinement Fusion under Cooperative Agreement No. DE-FC52-08NA28302.

  20. Phase error reduction in superconductive undulators using induction shimming

    Energy Technology Data Exchange (ETDEWEB)

    Drayer, Elisabeth; Bernhard, Axel; Afonso Rodriguez, Veronica; Grau, Andreas; Peiffer, Peter; Widmann, Christina; Baumbach, Tilo [KIT, Karlsruhe (Germany)

    2013-07-01

    The reduction of field errors in superconductive undulators is more demanding than in room temperature permanent magnet undulators. Various basic concepts exist but most of them have the disadvantage that they require field measurements at liquid-Helium temperature and modifications of the undulator coils at room temperature. Thus one or more thermal cycles are needed for an iterative improvement of the field quality. In order to avoid such a procedure it was proposed to cover the undulator coils with a thin layer of coupled superconductive loops which passively compensate the field errors via induction of persistent correction currents. In previous measurements this concept proved to work in principle and conclusions on an optimised shim configuration and field measurement setup could be drawn. In this paper we present the results of new measurements using one 12-period superconductive undulator short model and applying an optimised induction shim configuration. Due to further improvements of the field measurement setup these experiments for the first time give a quantitative indication of the phase error reduction efficiency of induction shimming.

  1. Enhanced Neonatal Brain Responses To Sung Streams Predict Vocabulary Outcomes By Age 18 Months.

    Science.gov (United States)

    François, Clément; Teixidó, Maria; Takerkart, Sylvain; Agut, Thaïs; Bosch, Laura; Rodriguez-Fornells, Antoni

    2017-09-29

    Words and melodies are some of the basic elements infants are able to extract early in life from the auditory input. Whether melodic cues contained in songs can facilitate word-form extraction immediately after birth remained unexplored. Here, we provided converging neural and computational evidence of the early benefit of melodies for language acquisition. Twenty-eight neonates were tested on their ability to extract word-forms from continuous flows of sung and spoken syllabic sequences. We found different brain dynamics for sung and spoken streams and observed successful detection of word-form violations in the sung condition only. Furthermore, neonatal brain responses for sung streams predicted expressive vocabulary at 18 months as demonstrated by multiple regression and cross-validation analyses. These findings suggest that early neural individual differences in prosodic speech processing might be a good indicator of later language outcomes and could be considered as a relevant factor in the development of infants' language skills.

  2. Passive shimming of a superconducting magnet using the L1-norm regularized least square algorithm.

    Science.gov (United States)

    Kong, Xia; Zhu, Minhua; Xia, Ling; Wang, Qiuliang; Li, Yi; Zhu, Xuchen; Liu, Feng; Crozier, Stuart

    2016-02-01

    The uniformity of the static magnetic field B0 is of prime importance for an MRI system. The passive shimming technique is usually applied to improve the uniformity of the static field by optimizing the layout of a series of steel shims. The steel pieces are fixed in the drawers in the inner bore of the superconducting magnet, and produce a magnetizing field in the imaging region to compensate for the inhomogeneity of the B0 field. In practice, the total mass of steel used for shimming should be minimized, in addition to the field uniformity requirement. This is because the presence of steel shims may introduce a thermal stability problem. The passive shimming procedure is typically realized using the linear programming (LP) method. The LP approach however, is generally slow and also has difficulty balancing the field quality and the total amount of steel for shimming. In this paper, we have developed a new algorithm that is better able to balance the dual constraints of field uniformity and the total mass of the shims. The least square method is used to minimize the magnetic field inhomogeneity over the imaging surface with the total mass of steel being controlled by an L1-norm based constraint. The proposed algorithm has been tested with practical field data, and the results show that, with similar computational cost and mass of shim material, the new algorithm achieves superior field uniformity (43% better for the test case) compared with the conventional linear programming approach.

  3. Learning sung lyrics aids retention in normal ageing and Alzheimer's disease.

    Science.gov (United States)

    Moussard, Aline; Bigand, Emmanuel; Belleville, Sylvie; Peretz, Isabelle

    2014-01-01

    Previous studies have suggested that presenting to-be-memorised lyrics in a singing mode, instead of a speaking mode, may facilitate learning and retention in normal adults. In this study, seven healthy older adults and eight participants with mild Alzheimer's disease (AD) learned and memorised lyrics that were either sung or spoken. We measured the percentage of words recalled from these lyrics immediately and after 10 minutes. Moreover, in AD participants, we tested the effect of successive learning episodes for one spoken and one sung excerpt, as well as long-term retention after a four week delay. Sung conditions did not influence lyrics recall in immediate recall but increased delayed recall for both groups. In AD, learning slopes for sung and spoken lyrics did not show a significant difference across successive learning episodes. However, sung lyrics showed a slight advantage over spoken ones after a four week delay. These results suggest that singing may increase the load of initial learning but improve long-term retention of newly acquired verbal information. We further propose some recommendations on how to maximise these effects and make them relevant for therapeutic applications.

  4. A general method of design of axial and radial shim coils for NMR and MRI magnets

    Energy Technology Data Exchange (ETDEWEB)

    Bobrov, E.S.; Punchard, W.F.B.

    1988-01-01

    The paper describes a general and efficient method of design of axial and radial shim coils to correct field impurities of various harmonic orders in regions of homogeneity of high resolution Nuclear Magnetic Resonance and Magnetic Resonance Imaging magnets.

  5. Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

    Index Scriptorium Estoniae

    Kim Sung Hong

    2009-01-01

    Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

  6. The effect of sung speech on socio-communicative responsiveness in children with Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Arkoprovo ePaul

    2015-10-01

    Full Text Available There is emerging evidence to demonstrate the efficacy of music based interventions for improving social functioning in children with Autism Spectrum Disorders (ASD. While this evidence lends some support in favour of using song over spoken directives in facilitating engagement and receptive intervention in ASD, there has been little research that has investigated the efficacy of such stimuli on socio-communicative responsiveness measures. Here, we present preliminary results from a pilot study which tested whether sung instruction, as compared to spoken directives, could elicit greater number of socio-communicative behaviours in young children with ASD. Using an adapted single-subject design, three children between the ages of 3 and 4 years, participated in a programme consisting of 18 sessions, of which 9 were delivered with spoken directives and 9 with sung. Sessions were counterbalanced and randomized for three play activities - block matching, picture matching and clay play. All sessions were video-recorded for post-hoc observational coding of three behavioural metrics which included performance, frequency of social gesture and eye contact. Analysis of the videos by two independent raters indicated increased socio-communicative responsiveness in terms of frequency of social gesture as well as eye contact during sung compared to spoken conditions across all participants. Our findings suggest that sung directives may play a useful role in engaging children with ASD and also serve as an effective interventional medium to enhance socio-communicative responsiveness.

  7. The Musical Foregrounding Hypothesis : How Music Influences the Perception of Sung Language

    NARCIS (Netherlands)

    Schotanus, Yke

    2015-01-01

    Abstract The question how music influences the perception of sung language is rather complicated. There are indications that music enhances lyric perception, but also that it obstructs it. Sometimes we are deeply moved by lyrics, sometimes we don’t even hear them. The linguistic concept of foregroun

  8. Children's Reading Comprehension and Narrative Recall in Sung and Spoken Story Contexts

    Science.gov (United States)

    Kouri, Theresa; Telander, Karen

    2008-01-01

    A growing number of reading professionals have advocated teaching literacy through music and song; however, little research exists supporting such practices. The purpose of this study was to determine if sung story book readings would enhance story comprehension and narrative re-tellings in children with histories of speech and language delay.…

  9. Words and melody are intertwined in perception of sung words: EEG and behavioral evidence.

    Directory of Open Access Journals (Sweden)

    Reyna L Gordon

    Full Text Available Language and music, two of the most unique human cognitive abilities, are combined in song, rendering it an ecological model for comparing speech and music cognition. The present study was designed to determine whether words and melodies in song are processed interactively or independently, and to examine the influence of attention on the processing of words and melodies in song. Event-Related brain Potentials (ERPs and behavioral data were recorded while non-musicians listened to pairs of sung words (prime and target presented in four experimental conditions: same word, same melody; same word, different melody; different word, same melody; different word, different melody. Participants were asked to attend to either the words or the melody, and to perform a same/different task. In both attentional tasks, different word targets elicited an N400 component, as predicted based on previous results. Most interestingly, different melodies (sung with the same word elicited an N400 component followed by a late positive component. Finally, ERP and behavioral data converged in showing interactions between the linguistic and melodic dimensions of sung words. The finding that the N400 effect, a well-established marker of semantic processing, was modulated by musical melody in song suggests that variations in musical features affect word processing in sung language. Implications of the interactions between words and melody are discussed in light of evidence for shared neural processing resources between the phonological/semantic aspects of language and the melodic/harmonic aspects of music.

  10. Words and melody are intertwined in perception of sung words: EEG and behavioral evidence.

    Science.gov (United States)

    Gordon, Reyna L; Schön, Daniele; Magne, Cyrille; Astésano, Corine; Besson, Mireille

    2010-03-31

    Language and music, two of the most unique human cognitive abilities, are combined in song, rendering it an ecological model for comparing speech and music cognition. The present study was designed to determine whether words and melodies in song are processed interactively or independently, and to examine the influence of attention on the processing of words and melodies in song. Event-Related brain Potentials (ERPs) and behavioral data were recorded while non-musicians listened to pairs of sung words (prime and target) presented in four experimental conditions: same word, same melody; same word, different melody; different word, same melody; different word, different melody. Participants were asked to attend to either the words or the melody, and to perform a same/different task. In both attentional tasks, different word targets elicited an N400 component, as predicted based on previous results. Most interestingly, different melodies (sung with the same word) elicited an N400 component followed by a late positive component. Finally, ERP and behavioral data converged in showing interactions between the linguistic and melodic dimensions of sung words. The finding that the N400 effect, a well-established marker of semantic processing, was modulated by musical melody in song suggests that variations in musical features affect word processing in sung language. Implications of the interactions between words and melody are discussed in light of evidence for shared neural processing resources between the phonological/semantic aspects of language and the melodic/harmonic aspects of music.

  11. Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

    Index Scriptorium Estoniae

    Kim Sung Hong

    2009-01-01

    Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

  12. The Musical Foregrounding Hypothesis : How Music Influences the Perception of Sung Language

    NARCIS (Netherlands)

    Schotanus, Yke

    2015-01-01

    Abstract The question how music influences the perception of sung language is rather complicated. There are indications that music enhances lyric perception, but also that it obstructs it. Sometimes we are deeply moved by lyrics, sometimes we don’t even hear them. The linguistic concept of

  13. The Musical Foregrounding Hypothesis : How Music Influences the Perception of Sung Language

    NARCIS (Netherlands)

    Schotanus, Yke

    2015-01-01

    Abstract The question how music influences the perception of sung language is rather complicated. There are indications that music enhances lyric perception, but also that it obstructs it. Sometimes we are deeply moved by lyrics, sometimes we don’t even hear them. The linguistic concept of foregroun

  14. Active shimming method for a 21.3 MHz small-animal MRI magnet

    Science.gov (United States)

    Chen, Shanshan; Xia, Tian; Miao, Zhiying; Xu, Luoyuan; Wang, Hongzhi; Dai, Shuguang

    2017-04-01

    In a 21.3 MHz animal nuclear magnetic resonance (NMR) analyzer and imaging system, high uniformity of the static field B 0 is a crucial prerequisite for obtaining high-quality images and detecting weak signals with short relaxation time. Using only passive shimming and gradient shimming, it is impossible to achieve perfect B 0 uniformity. This paper presents an approach involving high-order active shimming for an NMR analyzer and an imaging magnet. The diameter spherical volume (DSV) of the magnet is only 60 mm. The spherical harmonic function is introduced to analyze the magnetic field and provide a foundation for active shimming. Eleven pairs of bi-planar active shim coils (X, Y, Z, XZ, YZ, Z 2, X 2  +  Y 2, X 2  -  Y 2, Z 3, Z 4, Z 5) were designed using the target field-and stream-function methods, and coils were manufactured with printed circuit board technology in this research. The magnetic field created by these electrified shim coils compensates effectively and accurately for the static magnetic field B 0. The full width at half maximum of the resonance spectrum was used to measure the shimming effect. The results of practical shimming experiments in a 21.3 MHz animal NMR analyzer and imaging device showed that this new approach helps to reduce inhomogeneity from 24 ppm (24  ×  10-6) to 0.39 ppm (0.39  ×  10-6) over a 60 mm DSV, which meets the requirements of imaging and analytical practice.

  15. Enabling Object Storage via shims for Grid Middleware

    Science.gov (United States)

    Cadellin Skipsey, Samuel; De Witt, Shaun; Dewhurst, Alastair; Britton, David; Roy, Gareth; Crooks, David

    2015-12-01

    The Object Store model has quickly become the basis of most commercially successful mass storage infrastructure, backing so-called ”Cloud” storage such as Amazon S3, but also underlying the implementation of most parallel distributed storage systems. Many of the assumptions in Object Store design are similar, but not identical, to concepts in the design of Grid Storage Elements, although the requirement for ”POSIX-like” filesystem structures on top of SEs makes the disjunction seem larger. As modern Object Stores provide many features that most Grid SEs do not (block level striping, parallel access, automatic file repair, etc.), it is of interest to see how easily we can provide interfaces to typical Object Stores via plugins and shims for Grid tools, and how well experiments can adapt their data models to them. We present evaluation of, and first-deployment experiences with, (for example) Xrootd-Ceph interfaces for direct object-store access, as part of an initiative within GridPP[1] hosted at RAL. Additionally, we discuss the tradeoffs and experience of developing plugins for the currently-popular Ceph parallel distributed filesystem for the GFAL2 access layer, at Glasgow.

  16. Enabling Object Storage via shims for Grid Middleware

    CERN Document Server

    Skipsey, Samuel Cadellin; Dewhurst, Alastair; Britton, David; Roy, Gareth; Crooks, David

    2015-01-01

    The Object Store model has quickly become the basis of most commercially successful mass storage infrastructure, backing so-called "Cloud" storage such as Amazon S3, but also underlying the implementation of most parallel distributed storage systems. Many of the assumptions in Object Store design are similar, but not identical, to concepts in the design of Grid Storage Elements, although the requirement for "POSIX-like" filesystem structures on top of SEs makes the disjunction seem larger. As modern Object Stores provide many features that most Grid SEs do not (block level striping, parallel access, automatic file repair, etc.), it is of interest to see how easily we can provide interfaces to typical Object Stores via plugins and shims for Grid tools, and how well experiments can adapt their data models to them. We present evaluation of, and first-deployment experiences with, (for example) Xrootd-Ceph interfaces for direct object-store access, as part of an initiative within GridPP\\cite{GridPP} hosted at RAL....

  17. 40Ar-39Ar age of carbonatite-alkaline magmatism in Sung Valley, Maghalaya, India

    Indian Academy of Sciences (India)

    Jyotiranjan S Ray; Kanchan Pande

    2001-09-01

    40Ar-39Ar analyses of one alkali pyroxenite whole rock and two phlogopite separates of calcite carbonatites from the Sung Valley carbonatite-alkaline complex, which is believed to be a part of the Rajmahal-Bengal-Sylhet (RBS) ood basalt province, yielded indistinguishable plateau ages of 108.8 ± 2.0 Ma, 106:4 ± 1.3 Ma and 107.5 ± 1.4 Ma, respectively. The weighted mean of these ages, 107.2 ± 0.8 Ma, is the time of emplacement of this complex. This implies that Sung Valley complex and probably other such complexes in the Assam-Meghalaya Plateau postdate the main ood basalt event (i.e., the eruption of tholeiites) in the RBS province by ∼10 Ma.

  18. Dynamic Multi-Coil Shimming of the Human Brain at 7 Tesla

    Science.gov (United States)

    Juchem, Christoph; Nixon, Terence W.; McIntyre, Scott; Boer, Vincent O.; Rothman, Douglas L.; de Graaf, Robin A.

    2011-01-01

    High quality magnetic field homogenization of the human brain (i.e. shimming) for MR imaging and spectroscopy is a demanding task. The susceptibility differences between air and tissue are a longstanding problem as they induce complex field distortions in the prefrontal cortex and the temporal lobes. To date, the theoretical gains of high field MR have only been realized partially in the human brain due to limited magnetic field homogeneity. A novel shimming technique for the human brain is presented that is based on the combination of non-orthogonal basis fields from 48 individual, circular coils. Custom-built amplifier electronics enabled the dynamic application of the multi-coil shim fields in a slice-specific fashion. Dynamic multi-coil (DMC) shimming is shown to eliminate most of the magnetic field inhomogeneity apparent in the human brain at 7 Tesla and provided improved performance compared to state-of-the-art dynamic shim updating with zero through third order spherical harmonic functions. The novel technique paves the way for high field MR applications of the human brain for which excellent magnetic field homogeneity is a prerequisite. PMID:21824794

  19. Pregnant women models analyzed for RF exposure and temperature increase in 3T RF shimmed birdcages.

    Science.gov (United States)

    Murbach, Manuel; Neufeld, Esra; Samaras, Theodoros; Córcoles, Juan; Robb, Fraser J; Kainz, Wolfgang; Kuster, Niels

    2017-05-01

    MRI is increasingly used to scan pregnant patients. We investigated the effect of 3 Tesla (T) two-port radiofrequency (RF) shimming in anatomical pregnant women models. RF shimming improves B1(+) uniformity, but may at the same time significantly alter the induced current distribution and result in large changes in both the level and location of the absorbed RF energy. In this study, we evaluated the electrothermal exposure of pregnant women in the third, seventh, and ninth month of gestation at various imaging landmarks in RF body coils, including modes with RF shimming. Although RF shimmed configurations may lower the local RF exposure for the mother, they can increase the thermal load on the fetus. In worst-case configurations, whole-body exposure and local peak temperatures-up to 40.8°C-are equal in fetus and mother. Two-port RF shimming can significantly increase the fetal exposure in pregnant women, requiring further research to derive a very robust safety management. For the time being, restriction to the CP mode, which reduces fetal SAR exposure compared with linear-horizontal polarization modes, may be advisable. Results from this study do not support scanning pregnant patients above the normal operating mode. Magn Reson Med 77:2048-2056, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  20. Dynamic Multi-Coil Technique (DYNAMITE) Shimming for Echo-Planar Imaging of the Human Brain at 7 Tesla

    Science.gov (United States)

    Juchem, Christoph; Rudrapatna, S. Umesh; Nixon, Terence W.; de Graaf, Robin A.

    2014-01-01

    Gradient-echo echo-planar imaging (EPI) is the primary method of choice in functional MRI and other methods relying on fast MRI to image brain activation and connectivity. However, the high susceptibility of EPI towards B0 magnetic field inhomogeneity poses serious challenges. Conventional magnetic field shimming with low-order spherical harmonic (SH) functions is capable of compensating shallow field distortions, but performs poorly for global brain shimming or on specific areas with strong susceptibility-induced B0 distortions such as the prefrontal cortex (PFC). Excellent B0 homogeneity has been demonstrated recently in the human brain at 7 Tesla with the DYNAmic Multi-coIl TEchnique (DYNAMITE) for magnetic field shimming (Juchem et al., J Magn Reson (2011) 212:280-288). Here, we report the benefits of DYNAMITE shimming for multi-slice EPI and T2* mapping. A standard deviation of 13 Hz was achieved for the residual B0 distribution in the human brain at 7 Tesla with DYNAMITE shimming and was 60% lower compared to conventional shimming that employs static zero through third order SH shapes. The residual field inhomogeneity with SH shimming led to an average 8 mm shift at acquisition parameters commonly used for fMRI and was reduced to 1.5-3 mm with DYNAMITE shimming. T2* values obtained from the prefrontal and temporal cortices with DYNAMITE shimming were 10-50% longer than those measured with SH shimming. The reduction of the confounding macroscopic B0 field gradients with DYNAMITE shimming thereby promises improved access to the relevant microscopic T2* effects. The combination of high spatial resolution and DYNAMITE shimming allows largely artifact-free EPI and T2* mapping throughout the brain, including prefrontal and temporal lobe areas. DYNAMITE shimming is expected to critically benefit a wide range of MRI applications that rely on excellent B0 magnetic field conditions including EPI-based fMRI to study various cognitive processes and assessing large

  1. Mobility Impact on Session Survivability under the SHIM6 Protocol and Enhancement of its Rehoming Procedure

    Directory of Open Access Journals (Sweden)

    Amine Dhraief

    2011-11-01

    Full Text Available Multihoming is a solution that enables a fault-tolerant access to the Internet by configuring on each network entity several IP addresses associated with distinct ISPs. IPv6 natively allows end-hosts and end-sites to be multihomed where nodes and routers can have multiple IP addresses. However, a specific support is required to take full advantage of multihoming. The SHIM6 protocol provides such a support.We study in this paper to what extent the mobility impacts the SHIM6 protocol component in general and more specifically the context establishment as it is a \\textit{sine qua none} condition for session survivability. We focus on possible consequences of mobility before, during, and after the context establishment. We find that in some mobility scenarios, the SHIM6 context is never established and the session survivability cannot be ensured.

  2. [Cerebral paragonimiasis and Bo Sung Sim's hemispherectomy in Korea in 1950s-1960s].

    Science.gov (United States)

    Park, Jiyoung; Miyagawa, Takuya; Hong, Jeonghwa; Kim, Ockjoo

    2011-06-30

    This paper deals with cerebral paragonimiasis and cerebral hemispherectomy conducted as a treatment of cerebral paragonimiasis by Bo Sung Sim in Korea in 1950s-1960s. He demonstrated that cerebral hemispherectomy could be used for unilateral diffuse cerebral paragonimiasis. Sim learned cerebral hemispherectomy from Dr. L. A. French. at the University of Minnesota from 1955 to 1957 in America. The authors argues that Bo Sung Sim's introduction of cerebral hemispherectomy to Korea was not a simple application of an advanced medical technology, but a complicated and active process in that Sim used the technique to intervene intractable complications from cerebral paragonimiasis such as generalized convulsions, spastic hemiplegia and mental deterioration. Bo Sung Sim, one of the neurosurgeons of the first generation in Korea, was trained in neurology, neuropathology, neuroradiology and animal experiments as well as in neurosurgery at the University of Minnesota. After returning to Korea, Sim faced parasitic diseases, one of the most serious public health problems at that time, which were far different from what he learned in America. As a neurosurgeon, Sim tackled with parasitic diseases of the central nervous system with various diagnostics and therapeutics. In 1950s, more than one million populations suffered from pulmonary paragonimiasis acquired by eating raw crabs or by feeding juice of crushed crayfish for the treatment of measles in Korea. About 26.6 percent of people with paragonimiasis had cerebral paragonimiasis. Before bithionol therapy was introduced in 1962, neurosurgery was the only available treatment to control increased intracranial pressures, intractable epilepsy, paralysis and mental deterioration. Between 1958 to 1962, Bo Sung Sim operated on 24 patients of cerebral paragonimiasis. In two of them, he performed cerebral hemispherectomy to control intractable convulsions when he found diffuse cerebral paragonimiasis and cerebral atrophy at the

  3. Installation of the Main Magnet and Preliminary Results of Magnetic Mapping and Shimming for CYCIAE-100

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Tian-jue; LV; Yin-long; ZHONG; Jun-qing; XING; Jian-sheng; CAO; Lei; YANG; Jian-jun; WANG; Chuan; YAO; Hong-juan; CUI; Tao; LI; Ming; YIN; Zhi-guo; WANG; Zhen-hui; LIU; Geng-shou; LEI; Yu; ZOU; Jian; ZHAO; Jiang-bin

    2012-01-01

    <正>In 2012, the magnetic mapping and shimming for the main magnet of CYCIAE-100 has been carried out 4 times in the temporary building, realizing the goal of reducing the phase shift of the accelerating proton by 80%. A number of large scale equipments, including the main magnet, main coils, hydraulic elevating system, RF amplifier, magnetic mapper and vacuum chamber, have been in place for installation in the main building. The final stage magnetic mapping and shimming has started out as well.

  4. Prediction of forming limit strains of thin foils using shim

    Science.gov (United States)

    Joshi, Sanket Vivek; Bade, Rohit A.; Narasimhan, K.

    2013-12-01

    Thin foils of metallic alloys find utility in metallic thermal protection systems, such as honeycomb structures. Understanding the formability of these thin foils becomes imperative so as to design accurate tooling and also to ensure mechanical robustness of the honeycomb structures during service. It has been found that, obtaining the precise limit strains of these foils directly using the conventional limiting dome test tooling is difficult, because of the excessive draw in and wrinkling that occurs during the punch travel, resulting in erroneous measurement or prediction of limit strains. To address this issue, the blank over blank stacking methodology was developed, which helped keep the draw-in and wrinkling at negligible and thus acceptable levels. Although the blank over blank stacking methodology offers a way to predict and measure limit strains, the same may not be accurate enough due to the effect the substrate properties may impose on the thin foil. To avoid this effect, a different methodology has been proposed herein, which uses a shim stacked over the blank to avoid draw in of these foil blanks and thus help accurate clamping of the blank between the die and blank holder. It is thus understood that either a critical local or global increase in the thickness of the blank material in and around the draw bead is essential to obtain effective clamping of foil and to avoid draw-in and wrinkling. Although, miniaturized hemispherical dome tests may be beneficial for obtaining limit strains as far as foils are concerned, the methodologies proposed herein provide a route to obtaining the same using available equipment, thus saving resources and time involved in development of new miniaturized testing devices. The forming limit strains of thin foils of IN 718 (inconel) alloy having a thickness of 50μm, C263 (nimonic) alloy having a thickness of 100μm and CP Ti (commercially pure titanium) having a thickness of 200μm have been predicted using this methodology

  5. Effect of shim configuration on internal die flows for non-Newtonian coating liquids in slot coating process

    Science.gov (United States)

    Jin, Guang Lin; Ahn, Won-Gi; Kim, See Jo; Nam, Jaewook; Jung, Hyun Wook; Hyun, Jae Chun

    2016-05-01

    In this study, a strategy for designing optimal shim configuration inside a slot die is suggested to assure the uniform coating flow distribution of various non-Newtonian shear-thinning liquids at the die exit in a slot coating system. Flow patterns of non-Newtonian liquids inside the slot die, via three-dimensional computations, have been compared using various shim geometries which can adjust the flow region in a slot manifold. The rather non-uniform (parabolic) velocity distributions of shear-thinning liquids at the die exit under the basic shim condition could be effectively flattened by the modification of shim geometry without the change of die manifold structure. Dimensions of hybrid shims for controlling flow features at edge and center regions within slit channel are positively tuned, according to the shear-thinning level of coating liquids.

  6. Theoretical Formula and Simulation of Cyclotron Magnet Shimming in High Field Environment

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Dong-sheng; YANG; Jian-jun; LI; Ming

    2015-01-01

    In the computation of cyclotron magnet shimming,trim-rod and magnetic channel,one common process is to calculate the variation of magnet field caused by a small iron piece.Under the circumstance of superconducting cyclotron,high field approximate can be used and we can derive

  7. Shimming Halbach magnets utilizing genetic algorithms to profit from material imperfections.

    Science.gov (United States)

    Parker, Anna J; Zia, Wasif; Rehorn, Christian W G; Blümich, Bernhard

    2016-04-01

    In recent years, permanent magnet-based NMR spectrometers have resurfaced as low-cost portable alternatives to superconducting instruments. While the development of these devices as well as clever shimming methods have yielded impressive advancements, scaling the size of these magnets to miniature lengths remains a problem to be addressed. Here we present the results of a study of a discrete shimming scheme for NMR Mandhalas constructed from a set of individual magnet blocks. While our calculations predict a modest reduction in field deviation by a factor of 9.3 in the case of the shimmed ideal Mandhala, a factor of 28 is obtained in the case of the shimmed imperfect Mandhala. This indicates that imperfections of magnet blocks can lead to improved field homogeneity. We also present a new algorithm to improve the homogeneity of a permanent magnet assembly. Strategies for future magnet construction can improve the agreement between simulation and practical implementation by using data from real magnets in these assemblies as the input to such an algorithm to optimize the homogeneity of a given design.

  8. A new gradient shimming method based on undistorted field map of B0 inhomogeneity.

    Science.gov (United States)

    Bao, Qingjia; Chen, Fang; Chen, Li; Song, Kan; Liu, Zao; Liu, Chaoyang

    2016-04-01

    Most existing gradient shimming methods for NMR spectrometers estimate field maps that resolve B0 inhomogeneity spatially from dual gradient-echo (GRE) images acquired at different echo times. However, the distortions induced by B0 inhomogeneity that always exists in the GRE images can result in estimated field maps that are distorted in both geometry and intensity, leading to inaccurate shimming. This work proposes a new gradient shimming method based on undistorted field map of B0 inhomogeneity obtained by a more accurate field map estimation technique. Compared to the traditional field map estimation method, this new method exploits both the positive and negative polarities of the frequency encoded gradients to eliminate the distortions caused by B0 inhomogeneity in the field map. Next, the corresponding automatic post-data procedure is introduced to obtain undistorted B0 field map based on knowledge of the invariant characteristics of the B0 inhomogeneity and the variant polarity of the encoded gradient. The experimental results on both simulated and real gradient shimming tests demonstrate the high performance of this new method.

  9. A new gradient shimming method based on undistorted field map of B0 inhomogeneity

    Science.gov (United States)

    Bao, Qingjia; Chen, Fang; Chen, Li; Song, Kan; Liu, Zao; Liu, Chaoyang

    2016-04-01

    Most existing gradient shimming methods for NMR spectrometers estimate field maps that resolve B0 inhomogeneity spatially from dual gradient-echo (GRE) images acquired at different echo times. However, the distortions induced by B0 inhomogeneity that always exists in the GRE images can result in estimated field maps that are distorted in both geometry and intensity, leading to inaccurate shimming. This work proposes a new gradient shimming method based on undistorted field map of B0 inhomogeneity obtained by a more accurate field map estimation technique. Compared to the traditional field map estimation method, this new method exploits both the positive and negative polarities of the frequency encoded gradients to eliminate the distortions caused by B0 inhomogeneity in the field map. Next, the corresponding automatic post-data procedure is introduced to obtain undistorted B0 field map based on knowledge of the invariant characteristics of the B0 inhomogeneity and the variant polarity of the encoded gradient. The experimental results on both simulated and real gradient shimming tests demonstrate the high performance of this new method.

  10. Acoustic Features and Perceptive Cues of Songs and Dialogues in Whistled Speech: Convergences with Sung Speech

    CERN Document Server

    Meyer, Julien

    2007-01-01

    Whistled speech is a little studied local use of language shaped by several cultures of the world either for distant dialogues or for rendering traditional songs. This practice consists of an emulation of the voice thanks to a simple modulated pitch. It is therefore the result of a transformation of the vocal signal that implies simplifications in the frequency domain. The whistlers adapt their productions to the way each language combines the qualities of height perceived simultaneously by the human ear in the complex frequency spectrum of the spoken or sung voice (pitch, timbre). As a consequence, this practice underlines key acoustic cues for the intelligibility of the concerned languages. The present study provides an analysis of the acoustic and phonetic features selected by whistled speech in several traditions either in purely oral whistles (Spanish, Turkish, Mazatec) or in whistles produced with an instrument like a leaf (Akha, Hmong). It underlines the convergences with the strategies of the singing ...

  11. Measurements of vibrato parameters in long sustained crescendo notes as sung by ten sopranos.

    Science.gov (United States)

    Bretos, Jose; Sundberg, Johan

    2003-09-01

    Two high-pitched and long sustained notes, F5 and A5, were selected from an aria found in ten commercial recordings of G Verdi's opera Aida by ten different sopranos. Both notes were sung without any instrumental accompaniment and with a crescendo. These audio examples were analyzed with regard to fundamental frequency, vibrato rate, vibrato extent, intonation and sound level, and the relationship among these parameters. The results reveal that vibrato rate differed significantly between the tones in most of the singers and confirm Prame's observations that vibrato rate tends to increase exponentially toward the end of tones. Moreover, both vibrato extent and mean F0 often varied systematically with sound level. The regularity of the vibrato tended to be greater at F5 than at A5.

  12. Mitigating the impact of hohlraum asymmetries in National Ignition Facility implosions using capsule shims

    Science.gov (United States)

    Clark, D. S.; Weber, C. R.; Smalyuk, V. A.; Robey, H. F.; Kritcher, A. L.; Milovich, J. L.; Salmonson, J. D.

    2016-07-01

    Current indirect drive implosion experiments on the National Ignition Facility (NIF) [Moses et al., Phys. Plasmas 16, 041006 (2009)] are believed to be strongly impacted by long wavelength perturbations driven by asymmetries in the hohlraum x-ray flux. To address this perturbation source, active efforts are underway to develop modified hohlraum designs with reduced asymmetry imprint. An alternative strategy, however, is to modify the capsule design to be more resilient to a given amount of hohlraum asymmetry. In particular, the capsule may be deliberately misshaped, or "shimmed," so as to counteract the expected asymmetries from the hohlraum. Here, the efficacy of capsule shimming to correct the asymmetries in two recent NIF implosion experiments is assessed using two-dimensional radiation hydrodynamics simulations. Despite the highly time-dependent character of the asymmetries and the high convergence ratios of these implosions, simulations suggest that shims could be highly effective at counteracting current asymmetries and result in factors of a few enhancements in neutron yields. For higher compression designs, the yield improvement could be even greater.

  13. Mitigating the impact of hohlraum asymmetries in National Ignition Facility implosions using capsule shims

    Science.gov (United States)

    Clark, Daniel; Weber, Christopher; Smalyuk, Vladimir; Robey, Harry; Kritcher, Andrea; Milovich, Jose; Salmonson, Jay

    2016-10-01

    Current indirect drive implosion experiments on the National Ignition Facility (NIF) are believed to be strongly impacted by long wavelength perturbations driven by asymmetries in the hohlraum x-ray flux. To address this perturbation source, active efforts are underway to develop modified hohlraum designs with reduced asymmetry imprint. An alternative strategy, however, is to modify the capsule design to be more resilient to a given amount of hohlraum asymmetry. In particular, the capsule may be deliberately misshaped, or ``shimmed,'' so as to counteract the expected asymmetries from the hohlraum. Here, the efficacy of capsule shimming to correct the asymmetries in two recent NIF implosion experiments is assessed using two-dimensional radiation hydrodynamics simulations. Despite the highly time-dependent character of the asymmetries and the high convergence ratios of these implosions, simulations suggest that shims could be highly effective at counteracting current asymmetries and result in factors of a few enhancements in neutron yields. For higher compression designs, the yield improvement could be even greater. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  14. Quantitative Comparison of Minimum Inductance and Minimum Power Algorithms for the Design of Shim Coils for Small Animal Imaging.

    Science.gov (United States)

    Hudson, Parisa; Hudson, Stephen D; Handler, William B; Scholl, Timothy J; Chronik, Blaine A

    2010-04-01

    High-performance shim coils are required for high-field magnetic resonance imaging and spectroscopy. Complete sets of high-power and high-performance shim coils were designed using two different methods: the minimum inductance and the minimum power target field methods. A quantitative comparison of shim performance in terms of merit of inductance (ML) and merit of resistance (MR) was made for shim coils designed using the minimum inductance and the minimum power design algorithms. In each design case, the difference in ML and the difference in MR given by the two design methods was inductance designs tend to feature oscillations within the current density; while minimum power designs tend to feature less rapidly varying current densities and lower power dissipation. Overall, the differences in coil performance obtained by the two methods are relatively small. For the specific case of shim systems customized for small animal imaging, the reduced power dissipation obtained when using the minimum power method is judged to be more significant than the improvements in switching speed obtained from the minimum inductance method.

  15. Comparison of volume-selective z-shim and conventional EPI in fMRI studies using face stimuli

    CERN Document Server

    Fukunaga, Hu Cheng Srikanth Padmala Rena

    2013-01-01

    Single-shot gradient recalled echo planar imaging (EPI) is the primary tool for functional magnetic resonance imaging (fMRI). The image often suffers from signal drop near the air-tissue interface, such as the amygdala and regions of the orbitofrontal lobe. An effective way to correct for this type of artifact is by applying multi-shot EPI using different z-shimming. Unfortunately, the scanning efficiency is significantly lowered. More recently, a new technique called volume-selective z-shim was proposed to implement z-shim compensation to only specific slices with large susceptibility effects. The high imaging efficiency of volume selective z-shim makes it possible to substitute conventional EPI for whole brain studies. In this study two fMRI experiments were conducted to compare volume- selective z-shim and conventional EPI while subjects performed tasks on face stimuli. The comparison was focused on three brain regions: amygdala, hippocampus, and fusiform gyrus. Our results indicate that despite fewer volu...

  16. B1 homogeneity of breast MRI using RF shimming with individual specific values in volunteers simulating patients after mastectomy.

    Science.gov (United States)

    Abe, Takayuki

    2016-11-01

    Background Magnetic resonance imaging (MRI) using a 3-T MRI scanner is now widely used for clinical examinations. However, B1 inhomogeneity becomes larger with MRI scanners using 3-T and higher. It especially becomes a problem in the breast. To improve B1 homogeneity, a RF shimming technique has been developed. Purpose To evaluate the B1 homogeneity of breast MRI using RF shimming with individual specific values for subjects after mastectomy. Material and Methods The subjects are healthy female volunteers who underwent normal breast imaging, followed by imaging of one breast while the other breast was bound tightly to the chest by bleached cotton cloths (simulating volunteers after mastectomy). B1 mappings were performed with RF shimming using two techniques: (i) optimized fixed value; and (ii) individual specific values using a 3-T MRI scanner. The means and standard deviations of the B1 maps for all slices in the breast were measured and compared between the fixed value and the individual specific value cases. Results For normal volunteers, the breast B1 variation was not statistically significantly different between the RF shimming techniques. For volunteers after simulated surgery, the breast B1 variation was (1.02 ± 0.29) with the fixed value and (0.98 ± 0.22) with the individual specific value ( P volunteers after simulated surgery. Conclusion RF shimming with individual specific values has the potential to improve the B1 homogeneity of breast MRI in patients after mastectomy.

  17. The word and music of epic song: From syncretism to sung poetry

    Directory of Open Access Journals (Sweden)

    Lajić-Mihajlović Danka

    2013-01-01

    Full Text Available This study concerns the relationship between verbal and musical components of Serbian epic songs with rhythm seen as a morphological dominant. My aim is to enrich the musicological inquiry of this issue and provide a contribution that complements existing folkloristic and philological research outcomes. In terms of methodology, the study promotes the necessity of recording the performers’ recited versions of songs for the purposes of investigating the relationships between verbal and musical communication, as well as an interdisciplinary approach to these issues. Two paradigmatic examples are examined, each performed by the guslar representative of his respective period of guslar practice: Tanasije Vućić (1883-1937 and Boško Vujačić (b. 1947. The observed periods span less than one century, yielding an insignificant passage of time in terms of epic historicism, but nonetheless indicate significant differences between these two guslars’ sung and narrated rhythms. Compared to Vujačić, Vućić’s singing demonstrates a considerably smaller range of the absolute duration of the sung syllables (and therefore of an entire verse, and subsequently a much stricter syllabicity. Furthermore, Vućić’s singing reflects the ideal type of “isochronous pulse in duple meter” in a rather high degree, while Vujačić more consistently refers to narration, whereas the trochaic tendency is noticeable only at the initial part of the verse. The connections between these focused individual styles are discussed through the lens of guslars’ transition from amateur to professional capacity and the changed function of epics. Considering the consequences of the policy of invalid representation and experiencing epic song as poetry (void of musical component, and on the other hand, the effects of the strategy insistent on “citatory” (verbatim treatment of poetic templates that leads to suppressing poetic creativity, I intend to draw attention of the

  18. Variable power combiner for RF mode shimming in 7-T MR imaging.

    Science.gov (United States)

    Yazdanbakhsh, Pedram; Solbach, Klaus; Bitz, Andreas K

    2012-09-01

    This contribution discusses the utilization of RF power in an MRI system with RF mode shimming which enables the superposition of circularly polarized modes of a transmit RF coil array driven by a Butler matrix. Since the required power for the individual modes can vary widely, mode-shimming can result in a significant underutilization of the total available RF power. A variable power combiner (VPC) is proposed to improve the power utilization: it can be realized as a reconfiguration of the MRI transmit system by the inclusion of one additional matrix network which receives the power from all transmit amplifiers at its input ports and provides any desired (combined) power distribution at its output ports by controlling the phase and amplitude of the amplifiers' input signals. The power distribution at the output ports of the VPC is then fed into the "mode" ports of the coil array Butler matrix in order to superimpose the spatial modes at the highest achievable power utilization. The VPC configuration is compared to the standard configuration of the transmit chain of our MRI system with 8 transmit channels and 16 coils. In realistic scenarios, improved power utilization was achieved from 17% to 60% and from 14% to 55% for an elliptical phantom and a region of interest in the abdomen, respectively, and an increase of the power utilization of 1 dB for a region of interest in the upper leg. In general, it is found that the VPC allows significant improvement in power utilization when the shimming solution demands only a few modes to be energized, while the technique can yield loss in power utilization in cases with many modes required at high power level.

  19. Charakterisierung eines ultrahochmolekularen Polymethacrylats mit flüssigkristalliner Seitengruppe in verdünnter Lösung

    OpenAIRE

    Wenzel, Ulrike

    2000-01-01

    Durch radikalische Schmelzpolymerisation und anschließende Fällungsfraktionierung gewonnene ultrahochmolekulare Fraktionen des seitengruppenflüssigkristallinen Polymers Polymethacryloyloxy-hexadiyloxy-4´-methoxyphenylbenzoat (PMA-C6) wurden in verdünnter Lösung mittels Gelpermeationschromatographie, statischer Lichtstreuung und viskosimetrischen Methoden untersucht. Die thermodynamische Güte der untersuchten Lösemittel für PMA-C6 nimmt mit der Polarität in der Reihenfolge Toluol < Benzol < TH...

  20. Magic Realism, Neurodiversity, and Carnivalesque in James McBride’s Song Yet Sung

    Directory of Open Access Journals (Sweden)

    Yuan-Chin Chang

    2016-04-01

    Full Text Available This paper considers James McBride’s novel Song Yet Sung through multiple lenses – Bakhtin’s Carnivalesque, magic realism and performativity as it relates to race and gender identities. It is considered how the character of the “Dreamer” can be read clinically as suffering the sequelae of a traumatic brain injury. Her symptoms, which include future hallucinations or prophecies, can be read as neurological symptoms of her multiple head injuries documented in the novel. Connected to this reading, the influence of magic realism is considered, particularly as it relates to the natural imagery and symbolism in the novel. The importance of birds, in particular, is considered. Carnivalesque as conceptualized by Bakhtin is also considered in the context of “magical” thinking and reading, and its connections to social subversion; this is considered in relation to the era of slavery, its legacy, and associated issues of gender and race.Keywords: Carnivalesque, Magic Realism, Prophecy, Gender Performance, Racial Performativity, Identity Performance

  1. Cognitive priming in sung and instrumental music: activation of inferior frontal cortex.

    Science.gov (United States)

    Tillmann, B; Koelsch, S; Escoffier, N; Bigand, E; Lalitte, P; Friederici, A D; von Cramon, D Y

    2006-07-15

    Neural correlates of the processing of musical syntax-like structures have been investigated via expectancy violation due to musically unrelated (i.e., unexpected) events in musical contexts. Previous studies reported the implication of inferior frontal cortex in musical structure processing. However - due to the strong musical manipulations - activations might be explained by sensory deviance detection or repetition priming. Our present study investigated neural correlates of musical structure processing with subtle musical violations in a musical priming paradigm. Instrumental and sung sequences ended on related and less-related musical targets. The material controlled sensory priming components, and differences in target processing required listeners' knowledge on musical structures. Participants were scanned with functional Magnetic Resonance Imaging (fMRI) while performing speeded phoneme and timbre identification judgments on the targets. Behavioral results acquired in the scanner replicated the facilitation effect of related over less-related targets. The blood oxygen level-dependent (BOLD) signal linked to target processing revealed activation of right inferior frontal areas (i.e., inferior frontal gyrus, frontal operculum, anterior insula) that was stronger for less-related than for related targets, and this was independent of the material carrying the musical structures. This outcome points to the implication of inferior frontal cortex in the processing of syntactic relations also for musical material and to its role in the processing and integration of sequential information over time. In addition to inferior frontal activation, increased activation was observed in orbital gyrus, temporal areas (anterior superior temporal gyrus, posterior superior temporal gyrus and sulcus, posterior middle temporal gyrus) and supramarginal gyrus.

  2. Uncovering phenotypes of poor-pitch singing: The Sung Performance Battery (SPB

    Directory of Open Access Journals (Sweden)

    Magdalena eBerkowska

    2013-10-01

    Full Text Available Singing is as natural as speaking for humans. Increasing evidence shows that the layman can carry a tune (e.g., when asked to sing a well-known song or to imitate single pitches, intervals and short melodies. Yet, important individual differences exist in the general population with regard to singing proficiency. Some individuals are particularly inaccurate or imprecise in producing or imitating pitch information (poor-pitch singers, thus showing a variety of singing phenotypes. Unfortunately, so far there is not a standard set of tasks for assessing singing proficiency in the general population, allowing to uncover and characterize individual profiles of poor-pitch singing. Different tasks and analysis methods are typically used in various experiments, making the comparison of the results across studies arduous. To fill this gap we propose here a new tool for assessing singing proficiency (the Sung Performance Battery, SPB. The SPB starts from the assessment of participants’ vocal range followed by five tasks: 1 single-pitch matching, 2 pitch-interval matching, 3 novel-melody matching, 4 singing from memory of familiar melodies (with lyrics and on a syllable, and 5 singing of familiar melodies (with lyrics and on a syllable at a slow tempo indicated by a metronome. Data analysis via acoustical methods provides objective measures of pitch accuracy and precision in terms of absolute and relative pitch. The SPB has been tested in a group of 50 occasional singers. The results indicate that the battery is useful for characterizing proficient singing and for detecting cases of inaccurate and/or imprecise singing.

  3. Uncovering phenotypes of poor-pitch singing: the Sung Performance Battery (SPB)

    Science.gov (United States)

    Berkowska, Magdalena; Dalla Bella, Simone

    2013-01-01

    Singing is as natural as speaking for humans. Increasing evidence shows that the layman can carry a tune (e.g., when asked to sing a well-known song or to imitate single pitches, intervals and short melodies). Yet, important individual differences exist in the general population with regard to singing proficiency. Some individuals are particularly inaccurate or imprecise in producing or imitating pitch information (poor-pitch singers), thus showing a variety of singing phenotypes. Unfortunately, so far there is not a standard set of tasks for assessing singing proficiency in the general population, allowing to uncover and characterize individual profiles of poor-pitch singing. Different tasks and analysis methods are typically used in various experiments, making the comparison of the results across studies arduous. To fill this gap we propose here a new tool for assessing singing proficiency (the Sung Performance Battery, SPB). The SPB starts from the assessment of participants' vocal range followed by five tasks: (1) single-pitch matching, (2) pitch-interval matching, (3) novel-melody matching, (4) singing from memory of familiar melodies (with lyrics and on a syllable), and (5) singing of familiar melodies (with lyrics and on a syllable) at a slow tempo indicated by a metronome. Data analysis via acoustical methods provides objective measures of pitch accuracy and precision in terms of absolute and relative pitch. The SPB has been tested in a group of 50 occasional singers. The results indicate that the battery is useful for characterizing proficient singing and for detecting cases of inaccurate and/or imprecise singing. PMID:24151475

  4. SENSE shimming (SSH): A fast approach for determining B(0) field inhomogeneities using sensitivity coding.

    Science.gov (United States)

    Splitthoff, D N; Zaitsev, M

    2009-11-01

    The pursuit of ever higher field strengths and faster data acquisitions has led to the construction of coil arrays with high numbers of elements. With the sensitivity encoding (SENSE) technique, it has been shown that the sensitivity of those elements can be used for spatial image encoding. Here, a proof-of-principle is presented of a method that can be considered an extreme case of the SENSE approach, completely abstaining from using encoding gradients. The resulting sensitivity encoded free-induction decay (FID) data are then not used for imaging, but for determining B(0) field inhomogeneity distribution. The method has therefore been termed "SENSE shimming" (SSH). In phantom experiments the method's ability to detect inhomogeneities of up to the second order is demonstrated.

  5. Der Tod im Leben. Einige Grundgedanken zu und aus Franz Rosenzweigs der Stern der Erlösung

    Directory of Open Access Journals (Sweden)

    Brasser Martin

    2012-01-01

    Full Text Available Franz Rosenzweig gilt als Existenzphilosoph, weil er das Thema des Todes ins Zentrum der Argumentation in seinem philosophisch-theologischen Hauptwerk Der Stern der Erlösung gestellt hat. Die Religion wird dort als der Ort verstanden, an dem der Tod nicht mehr wie im a-religiösen Leben aus dem Leben herausgedrängt werden muss. Wenn Religion Liebe ist, dann ist der Tod so Teil des Lebens wie er Teil der Liebe zwischen zwei Liebenden ist: als bejahter Bestandteil ihres gemeinsamen Lebens. Der Aufsatz versucht diese Argumentation nachzuzeichnen und zu plausibilisieren.

  6. Gain of Imaging Fidelity by Employing a Higher Number of Independent Transmit Channels Together with Slice-Selective Radio-Frequency (RF Shimming at 7T

    Directory of Open Access Journals (Sweden)

    Niravkumar Darji

    2013-12-01

    Full Text Available Dielectric resonance effects and radio-frequency (RF power deposition have become challenging issues for magnetic resonance imaging at ultrahigh-field (UHF strengths. The use of transmit (Tx coil arrays with independently-driven RF sources using a parallel transmission system is a promising method for alleviating the resulting RF inhomogeneities. In this study, the effect on homogeneity and RF-power when employing a higher number of transmit channels with multi-slice acquisition in vivo at high field strength (7T is scrutinized. An 8-channel head coil array was driven to emulate circular polarized (CP and 2-, 4-, and 8-channel independent transmit configurations at 7T. Static RF shimming was employed on human subjects in order to homogenize the B1+ field in the excited volume. Slice-selective and global RF shimming methods were applied with CP and 2-, 4-, and 8-channel transmit channel configurations. RF shimming was performed from CP to 2-, 4-, and 8-channel Tx configurations globally and slice-selectively. Systematic improvement in B1+ homogeneity and/or reduction in RF-power were observed. RF shimming in the human brain with 8-channel transmit and slice-selective shimming yields an increase in B1+ homogeneity of 43% and/or reduces RF-power by 68% when compared with CP global RF shimming at 7T.

  7. Perception of a Sung Vowel as a Function of Frequency-Modulation Rate and Excursion in Listeners with Normal Hearing and Hearing Impairment

    Science.gov (United States)

    Vatti, Marianna; Santurette, Sébastien; Pontoppidan, Niels Henrik; Dau, Torsten

    2014-01-01

    Purpose: Frequency fluctuations in human voices can usually be described as coherent frequency modulation (FM). As listeners with hearing impairment (HI listeners) are typically less sensitive to FM than listeners with normal hearing (NH listeners), this study investigated whether hearing loss affects the perception of a sung vowel based on FM…

  8. Magnetic levitation performance of high-temperature superconductor over three magnetic hills of permanent magnet guideway with iron shims of different thicknesses

    Institute of Scientific and Technical Information of China (English)

    Yuming Gong; Gang Liang; Lifeng Zhao; Yong Zhang; Yong Zhao; Xuyong Chen

    2014-01-01

    Superconducting magnetic levitation perfor-mance, including levitation force and guidance force, is important for the application of high-temperature super-conducting maglev. Both of them are not only affected by different arrays of superconductors and magnets, but also by the thickness of the iron shim between permanent magnets. In order to obtain the best levitation performance, the magnetic field distribution, levitation force, and guid-ance force of a new type of three magnetic hills of per-manent magnet guideway with iron shim of different thicknesses (4, 6, and 8 mm) are discussed in this paper. Simulation analysis and experiment results show that the guideway with iron shim of 8 mm thickness possesses the strongest magnetic field and levitation performance when the suspension gap is larger than 10 mm. However, with the decreasing of suspension gap, the guideway with iron shim of 4 mm thickness possesses the best levitation per-formance. The phenomena can be attributed to the density distribution of flux and magnetization of iron shim.

  9. Still shimming or already measuring? - Quantitative reaction monitoring for small molecules on the sub minute timescale by NMR

    Science.gov (United States)

    Kind, J.; Thiele, C. M.

    2015-11-01

    In order to enable monitoring of rapidly occurring reactions Wagner et al. recently presented a simple scheme for 1D NMR experiments with continuous data acquisition, without inter-scan delays, using a spatially-selective and frequency-shifted excitation approach (Wagner et al., 2013). This scheme allows acquisition of proton spectra with temporal resolutions on the millisecond timescale. Such high temporal resolutions are desired in the case of reaction monitoring using stopped flow setups. In regular 1H NMR-spectra without spatial selection the line width increases for a given shim setting with changes in sample volume, susceptibility, convection and temperature or concentration gradients due to the disturbance of magnetic field homogeneity. Concerning reaction monitoring this is unfortunate as shimming prior to acquisition becomes necessary to obtain narrow signals after injection of a reactant into an NMR sample. Even automatic shim routines may last up to minutes. Thus fast reactions can hardly be monitored online without large hardware dead times in a single stopped flow experiment. This problem is reduced in the spatially-selective and frequency-shifted continuous NMR experiment as magnetic field inhomogeneties are less pronounced and negative effects on the obtained line shapes are reduced as pointed out by Bax and Freeman (1980) [2] and demonstrated by Wagner et al. (2013). Here we present the utilization of this technique for observation of reactions in small molecule systems in which chemical conversion and longitudinal relaxation occur on the same timescale. By means of the alkaline ethyl acetate hydrolysis, a stoichiometric reaction, we show advantages of spatially-selective excitation on both temporal resolution and line shapes in stopped flow experiments. Results are compared to data obtained by non-selective small angle excitation experiments.

  10. Perception of a Sung Vowel as a Function of Frequency-Modulation Rate and Excursionin Normal-Hearing and Hearing-Impaired Listeners

    DEFF Research Database (Denmark)

    Vatti, Marianna; Santurette, Sébastien; Pontoppidan, Niels henrik

    2014-01-01

    affects the perception of a sung vowel based on FM cues. Method: Vibrato maps were obtained in 14 NH and 12 HI listeners with different degrees of musical experience. The FM rate and FM excursion of a synthesized vowel, to which coherent FM was applied, were adjusted until a singing voice emerged. Results......: In NH listeners, adding FM to the steady vowel components produced perception of a singing voice for FM rates between 4.1 and 7.5 Hz and FM excursions between 17 and 83 cents on average. In contrast, HI listeners showed substantially broader vibrato maps. Individual differences in map boundaries were......, overall, not correlated with audibility or frequency selectivity at the vowel fundamental frequency, with no clear effect of musical experience. Conclusion: Overall, it was shown that hearing loss affects the perception of a sung vowel based on FM-rate and FM-excursion cues, possibly due to deficits in FM...

  11. Development of Feature Set, Classification Implementation and Applications for Vowel Migration/Modification in Sung Filipino (Tagalog Texts and Perceived Intelligibility

    Directory of Open Access Journals (Sweden)

    Virginia B. Bustos

    2009-12-01

    Full Text Available With the emergence of research on real-time visual feedback to supplement vocal pedagogy, the utilization of technology in the world of music is now seen to accelerate skills learning and enhance cognitive development. The researchers of this project aim to further analyze vowel intelligibility and develop software applications intended to be used not only by professional singers but also by individuals who wish to improve their singing capability. Data in the form of sung vowels and song pieces were obtained from 46 singers. A Listening Test was then conducted on these samples to obtain the ground truth for vowel classification based on human perception. Simulation of the human auditory perception of sung Filipino vowels was performed using formant frequencies and Mel-frequency cepstral coefficients as feature vector inputs to a two-stage Discriminant Analysis classifier. The setup resulted in an over-all Training Set accuracy of 89.4% and an over-all Test Set accuracy of 90.9%. The accuracy of the classifier, measured in terms of the correspondence of vowel classifications obtained from the classifier with the results of the Listening Test, reached 92.3%. Using information obtained from the classifier, offline and online/real-time software applications were developed. The main application features include the display of the spectral envelope and spectrogram, pitch and vibrato analysis and direct feedback on the classification of the sung vowel. These features were recommended by singers who were surveyed and were incorporated in the applications to aid singers to adjust formant locations, directly determine listener’s perception of sung vowels, perform modeling effectively and carry out vowel migration.

  12. Kalium-39-NMR in-vivo am Menschen bei 7Tesla: 39K-MR-Bildgebung und Auflösung der Quadrupolaufspaltung der 39K-Resonanz

    OpenAIRE

    Rösler, Manuela Barbara

    2015-01-01

    In dieser Arbeit wurde die Machbarkeit der In-vivo-39K-MR-Bildgebung am menschlichen Oberschenkel sowie am Kopf mit einer nominellen Auflösung von 1 cm3 in einer Messzeit von 30 min bei einer Grundmagnetfeldstärke von 7T gezeigt. Zur Optimierung der Sequenzparameter wurden sowohl die globalen Relaxationszeitkonstanten bestimmt. In Untersuchungsregionen mit hohem Muskelanteil, wie im Ober- und Unterschenkel, ist die Resonanz von 39K in ein Triplett aufgespalten. Die beiden Satellitenresona...

  13. Extended RF shimming: Sequence-level parallel transmission optimization applied to steady-state free precession MRI of the heart.

    Science.gov (United States)

    Beqiri, Arian; Price, Anthony N; Padormo, Francesco; Hajnal, Joseph V; Malik, Shaihan J

    2017-06-01

    Cardiac magnetic resonance imaging (MRI) at high field presents challenges because of the high specific absorption rate and significant transmit field (B1(+) ) inhomogeneities. Parallel transmission MRI offers the ability to correct for both issues at the level of individual radiofrequency (RF) pulses, but must operate within strict hardware and safety constraints. The constraints are themselves affected by sequence parameters, such as the RF pulse duration and TR, meaning that an overall optimal operating point exists for a given sequence. This work seeks to obtain optimal performance by performing a 'sequence-level' optimization in which pulse sequence parameters are included as part of an RF shimming calculation. The method is applied to balanced steady-state free precession cardiac MRI with the objective of minimizing TR, hence reducing the imaging duration. Results are demonstrated using an eight-channel parallel transmit system operating at 3 T, with an in vivo study carried out on seven male subjects of varying body mass index (BMI). Compared with single-channel operation, a mean-squared-error shimming approach leads to reduced imaging durations of 32 ± 3% with simultaneous improvement in flip angle homogeneity of 32 ± 8% within the myocardium. © 2017 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd.

  14. Gradient shimming during magnetic resonance imaging of the liver: comparison of a standard protocol versus a novel reduced protocol.

    Science.gov (United States)

    Bashir, Mustafa R; Dale, Brian M; Gupta, Rajan T; Horvath, Jeffrey J; Boll, Daniel T; Merkle, Elmar M

    2012-09-01

    The aim of this study was to examine the effect of minimizing prescan adjustments on table time and image quality in magnetic resonance imaging (MRI) of the liver. This prospective Health Insurance Portability and Accountability Act-compliant study was approved by the institutional review board, and written informed consent was obtained. Ten volunteers were imaged twice using a noncontrast liver MRI protocol consisting of a total of 10 pulse sequences, once with a standard protocol and once with a fixed table position/minimized prescan adjustment protocol (in random order). Total examination time was evaluated according to a Lean Six Sigma framework. Quantitative sequences, including diffusion-weighted imaging with apparent diffusion coefficient, multi-echo Dixon fat percentage, and the transverse relaxation time, were evaluated and compared between the two protocols. Two experienced readers, blinded to the protocol used, compared image quality between the two protocols. The average number of prescan adjustment steps per examination was reduced from 58.0 to 22.1 using the minimal shimming protocol compared with the normal shimming protocol (P < 0.001). Mean business value added time (scan preparatory time) was reduced by 58% (3 minutes 3 seconds vs 7 minutes 13 seconds), whereas mean total examination time was 20% lower (18 minutes 13 seconds vs 22 minutes 48 seconds, P < 0.001). Quantitative measures obtained using the two protocols were equivalent, and neither reader detected a significant difference in subjective image quality. Fixing table position minimizes prescan adjustments and reduces total table time in liver MRI without adversely affecting image quality.

  15. [Missionary Medicine of Canadian Presbytery and Korean Doctors under Japanese Occupation--focusing Sung-jin and Ham-heung].

    Science.gov (United States)

    Heo, Yun-Jung; Cho, Young-Soo

    2015-12-01

    In East Asia during the second half of the 19th century, overseas mission work by Protestant churches thrived. Missionaries built schools and hospitals and effectively used them for evangelism. In the 20th century when Social Gospel Movement was expanding, medical work has been recognized as a significant mission service in and by itself. This article reviewed the construction and characteristics of missions work conducted by Canadian Presbytery; missionary doctors and Korean doctors who worked at the mission hospitals; why the missionary medical work had to stop; and career paths taken by Korean doctors upon liberation from Japanese occupation. The Canadian Presbytery missionaries, unlike other denomination missionaries, were rather critical of Imperial Japan, but supportive towards Koreans. This could have stemmed from the reflection of their own experience of once a colony of British Empire and also their value system that promotes egalitarian, democratic and progressive theology. The Sung-jin and Ham-heung Mission Bases were a community, interacting organically as a 'Triangle of Church, School and Hospital.' The missionaries mobilized the graduates from Christian schools and organized a Young Men's Christian Association (YMCA). Some of the graduates were trained to become medical doctors or assistants and worked at mission hospitals. Missionary doctors' approaches to balancing evangelism and medical practice varied. For example, Robert Grieson went through confusion and struggled to balance conflicting roles as a pastor for evangelism and also as a physician. Kate McMillan, on the other hand, had less burden for evangelism than Grieson, and focused on medical work by taking advantage of the opportunity that, as a woman, she can easily approach Korean women. Still another case was Florence Murray who practised evangelism within the hospital setting, and successfully carried out the role as a hospital administrator, going beyond 'women's work' as McMillan did

  16. Interaction between bottom-up and top-down effects during the processing of pitch intervals in sequences of spoken and sung syllables.

    Science.gov (United States)

    Angenstein, Nicole; Scheich, Henning; Brechmann, André

    2012-07-02

    The processing of pitch intervals may be differentially influenced when musical or speech stimuli carry the pitch information. Most insights into the neural basis of pitch interval processing come from studies on music perception. However, music, in contrast to speech, contains a stable set of pitch intervals. To converge the investigation of pitch interval processing in music and speech, we used sequences of the same spoken or sung syllables. The pitch of these syllables varied either by semitone steps like in music or by smaller intervals. Participants had to differentiate the sequences according to their different sizes of pitch intervals or to the direction of the last frequency step in the sequence. The results depended strongly on the specific task demands. Whereas the interval-size task itself recruited more regions in right lateralized fronto-parietal brain network, stronger activity on semitone than on non-semitone sequences was found in the left hemisphere (mainly in frontal cortex) during this task. These effects were also influenced by the speech mode (spoken or sung syllables). Our findings suggest that the processing of pitch intervals in sequences of syllables depends on an interaction between bottom-up (speech mode, pitch interval) and top-down effects (task). Copyright © 2012 Elsevier Inc. All rights reserved.

  17. Structural shimming for high-resolution nuclear magnetic resonance spectroscopy in lab-on-a-chip devices.

    Science.gov (United States)

    Ryan, Herbert; Smith, Alison; Utz, Marcel

    2014-05-21

    High-resolution proton NMR spectroscopy is well-established as a tool for metabolomic analysis of biological fluids at the macro scale. Its full potential has, however, not been realised yet in the context of microfluidic devices. While microfabricated NMR detectors offer substantial gains in sensitivity, limited spectral resolution resulting from mismatches in the magnetic susceptibility of the sample fluid and the chip material remains a major hurdle. In this contribution, we show that susceptibility broadening can be avoided even in the presence of substantial mismatch by including suitably shaped compensation structures into the chip design. An efficient algorithm for the calculation of field maps from arbitrary chip layouts based on Gaussian quadrature is used to optimise the shape of the compensation structure to ensure a flat field distribution inside the sample area. Previously, the complexity of microfluidic NMR systems has been restricted to simple capillaries to avoid susceptibility broadening. The structural shimming approach introduced here can be adapted to virtually any shape of sample chamber and surrounding fluidic network, thereby greatly expanding the design space and enabling true lab-on-a-chip systems suitable for high-resolution NMR detection.

  18. Shimming with permanent magnets for the x-ray detector in a hybrid x-ray/ MR system.

    Science.gov (United States)

    Wen, Zhifei; Fahrig, Rebecca; Williams, Scott T; Pelc, Norbert J

    2008-09-01

    In this x-ray/MR hybrid system an x-ray flat panel detector is placed under the patient cradle, close to the MR volume of interest (VOI), where the magnetic field strength is approximately 0.5 T. Immersed in this strong field, several electronic components inside the detector become magnetized and create an additional magnetic field that is superimposed on the original field of the MR scanner. Even after linear shimming, the field homogeneity of the MR scanner remains disrupted by the detector. The authors characterize the field due to the detector with the field of two magnetic dipoles and further show that two sets of permanent magnets (NdFeB) can withstand the main magnetic field and compensate for the nonlinear components of the additional field. The ideal number of magnets and their locations are calculated based on a field map measured with the detector in place. Experimental results demonstrate great promise for this technique, which may be useful in many settings where devices with magnetic components need to be placed inside or close to an MR scanner.

  19. Asepsis Sowing and in vitro Propagation of Brassolaeliocattleya Sung Ya Green%卡特兰无菌播种与快速繁殖

    Institute of Scientific and Technical Information of China (English)

    郑宝强; 王雁; 彭镇华

    2010-01-01

    @@ 1 植物名称 卡特兰杂交种(Brassolaeliocattleya Sung Ya Green'Green World'). 2材料类别 人工自花授粉后90、120、150、180和210 d的种子. 3培养条件 种子萌发培养基:(1)KC;(2)MS;(3)1/2MS.原球茎诱导、增殖和分化培养基:(4)1/2MS+NAA 0.2 mg·L-1(单位下同);(5)1/2MS+NAA 0.4;(6)1/2MS+6-BA 0.5+NAA 0.2;(7)1/2MS+6-BA 1.0+NAA0.2.

  20. 3D GABA imaging with real-time motion correction, shim update and reacquisition of adiabatic spiral MRSI.

    Science.gov (United States)

    Bogner, Wolfgang; Gagoski, Borjan; Hess, Aaron T; Bhat, Himanshu; Tisdall, M Dylan; van der Kouwe, Andre J W; Strasser, Bernhard; Marjańska, Małgorzata; Trattnig, Siegfried; Grant, Ellen; Rosen, Bruce; Andronesi, Ovidiu C

    2014-12-01

    Gamma-aminobutyric acid (GABA) and glutamate (Glu) are the major neurotransmitters in the brain. They are crucial for the functioning of healthy brain and their alteration is a major mechanism in the pathophysiology of many neuro-psychiatric disorders. Magnetic resonance spectroscopy (MRS) is the only way to measure GABA and Glu non-invasively in vivo. GABA detection is particularly challenging and requires special MRS techniques. The most popular is MEscher-GArwood (MEGA) difference editing with single-voxel Point RESolved Spectroscopy (PRESS) localization. This technique has three major limitations: a) MEGA editing is a subtraction technique, hence is very sensitive to scanner instabilities and motion artifacts. b) PRESS is prone to localization errors at high fields (≥3T) that compromise accurate quantification. c) Single-voxel spectroscopy can (similar to a biopsy) only probe steady GABA and Glu levels in a single location at a time. To mitigate these problems, we implemented a 3D MEGA-editing MRS imaging sequence with the following three features: a) Real-time motion correction, dynamic shim updates, and selective reacquisition to eliminate subtraction artifacts due to scanner instabilities and subject motion. b) Localization by Adiabatic SElective Refocusing (LASER) to improve the localization accuracy and signal-to-noise ratio. c) K-space encoding via a weighted stack of spirals provides 3D metabolic mapping with flexible scan times. Simulations, phantom and in vivo experiments prove that our MEGA-LASER sequence enables 3D mapping of GABA+ and Glx (Glutamate+Gluatmine), by providing 1.66 times larger signal for the 3.02ppm multiplet of GABA+ compared to MEGA-PRESS, leading to clinically feasible scan times for 3D brain imaging. Hence, our sequence allows accurate and robust 3D-mapping of brain GABA+ and Glx levels to be performed at clinical 3T MR scanners for use in neuroscience and clinical applications.

  1. COMPARATION STUDY OF INSTANT NOODLE NONG SHIM KOREA AND INDOMIE INDONESIA AS THE FEFFECT OF PACKAGING DESIGN POINT OF INTEREST TO THE CONSUMER BRAND PREFERENCE

    Directory of Open Access Journals (Sweden)

    Listia Natadjaja

    2003-01-01

    Full Text Available Sudah sejak lama%2C masyarakat mengkonsumsi mie instant. Di Korea mi instan yang disebut Ramyon%2C adalah salah satu makanan yang popular dan banyak dijual di toko-toko kecil%2C supermarket%2C restoran dan kantin. Mi instan yang terkenal di Korea diproduksi oleh Nong Shim Co.%2C Ltd. Di Indonesia%2C kebanyakan orang mengkonsumsi mi instan dengan alasan praktis%2C cepat saji dan lain sebagainya. Indomie%2C yang diproduksi oleh PT. Indofood adalah merk nomor satu dan menjadi pemimpin pasar pada pasar mi instan. Dalam studi komparasi antara dua merk terkenal ini%2C perlu diketahui seberapa jauh peran desain kemasan dalam menarik minat konsumen terhadap pilihan merk. Abstract in Bahasa Indonesia : For a long time%2C people have consumed the instant noodle. In Korea%2C instant noodle%2C which is called Ramyon%2C is one of popular food and it is often seen in the retail shop%2C supermarket%2C restaurant and cafeteria. Instant noodle that has a famous brand in Korea is produce by Nong Shim Co.%2C Ltd. In Indonesia%2C many people have consumed the instant noodle with practice reason%2C fast serving%2C and etc. Indomie%2C produced by PT. Indofood%2C is the number one brand and become the market leader of instant noodle. Comparing at two famous brand of instant noodle%2C it is needed to be known how far the effect of packaging design can attract the consumer brand preference. desain kemasan%2C pilihan merk%2C mi instan.

  2. Transfer-Effizienz beim Übersetzen der humoristischen Stilelemente in der slowenischen Übersetzung von Kerstin Giers Roman "Für jede Lösung ein Problem"

    OpenAIRE

    2014-01-01

    Die vorliegende Magisterarbeit versuchte sich mit der Übersetzung des Humors am Beispiel des Kerstin Giers Romans „Für jede Lösung ein Problem“ auseinanderzusetzen und die Transfer-Effizienz der humoristischen Stilelemente in der slowenischen Übersetzung zu bewerten bzw. zu überprüfen. Die vorausgesetzte These lautete, dass die slowenische Übersetzung weniger humorvoll ist als das deutsche Original. Um die These zu bestätigen oder zu verwerfen, wurde eine Stilanalyse des Romans durchgeführt, ...

  3. Two-voxel spectroscopy with dynamic B0 shimming and flip angle adjustment at 7 T in the human motor cortex.

    Science.gov (United States)

    Lemke, Clark; Hess, Aaron; Clare, Stuart; Bachtiar, Velicia; Stagg, Charlotte; Jezzard, Peter; Emir, Uzay

    2015-07-01

    The aim of this study was to acquire high-quality in vivo (1) H spectra concurrently from two voxels at ultra-high field (7 T) without specialized hardware. To this end, an acquisition scheme was developed in which first-order shims and flip angles are dynamically updated to acquire spectra from both of the brain's motor cortices in an alternating fashion. To validate this acquisition scheme, separate, static, single-voxel acquisitions were also performed for comparison. Six subjects were examined using semi-LASER spectroscopy at 7 T. Barium titanate pads were used to increase the extent of the effective transmit field (B1 (+) ). Spectra were obtained from the hand area of both motor cortices for both acquisition schemes. LCModel was used to determine neurochemical profiles in order to examine variations between acquisition schemes and volumes of interest. The dynamic two-voxel acquisition protocol produced water linewidths (full width at half-maximum between 11.6 and 12.8 Hz) and signal-to-noise ratios similar to those from static single-voxel measurements. The concentrations of 13 individual and 3 combined metabolites with Cramér-Rao lower bounds below 30% were reliably detected for both acquisition schemes, and agreed well with previous postmortem assay and spectroscopy studies. The results show that high spectral quality from two voxels can be acquired concurrently without specialized hardware. This practical technique can be applied to many neuroscience applications.

  4. 基于虚拟样机的回旋加速器主磁铁设计与修正%Magnet design and shimming of cyclotrons based on virtual prototyping

    Institute of Scientific and Technical Information of China (English)

    秦斌; 樊明武; 陈德智

    2007-01-01

    磁铁设计对于等时性回旋加速器极为关键.磁场分布需要满足粒子等时性加速和粒子径向、轴向聚集要求,同时避免危险的横向共振.提出了一种计算机辅助的自动化磁铁设计、建模和修正的方法,该方法在基于Python混合编程的虚拟样机集成设计环境中实现.详细描述了利用3维电磁场仿真软件TOSCA和自主开发的粒子束跟踪软件PTP对磁铁的优化过程,并给出了一个16 MeV负氢紧凑型回旋加速器的主磁铁设计实例.%Magnet design and modeling is a crucial task in the design of cyclotrons, which includes iterative processes from an initial model. The magnetic field distribution should fulfill the requirements of isochronisms and transverse focusing of the beam, as well as avoiding dangerous resonance crossing. This paper introduces an automated magnet design, modeling and shimming method under the pythonic integrated environment based on virtual prototyping, a novel technique to shorten development period and reduce costs for physical prototypes. Detailed magnet shimming processes with the support of the 3D magnetic field simulation code TOSCA and an original developed particle tracking code PTP are described. As a case study, the main magnet design of a 16 MeV H- compact isochronous cyclotron is illustrated and validated in a virtual prototype.

  5. 液化石油气二甲醚混合燃料用橡胶密封圈安全性能的试验研究%Experimental Study on Safety Property of LPGDME Rubber Shim

    Institute of Scientific and Technical Information of China (English)

    徐晓丹; 万晓宁; 朱平; 郭培杰; 何华

    2012-01-01

    Taking fluorine rubber and Buna-N rubber seal for examples, and according to GB 7512-2006 Cylinders Valve of Liquefied Petroleum Gas and an enterprise standard Dimethyl Ether Rubber Seal Material, the corrosion-resisting test, the ageing resistance test and the low temperature resistance test were implemented in LPGDME with different proportioning. The test results indicate that both volume change rate and mass change rate of two samples can change with the ratio of dimethyl ether, but the mass change rate of Buna-N rubber can change obviously with the ratio change of combined fuel and the results of ageing resistance test and low temperature resistance test are acceptable. Under the same ratio of reagents, the corrosion resistance property of fluorine rubber outperforms that of common Buna-N Rubber, and the safety property of fluorine rubber shim can meet the standard requirements, and it' s applicable to LPGDME cylinder.%以氟橡胶和普通丁腈橡胶两种橡胶密封圈为样本,分别参照GB 7512-2006《液化石油气瓶阀》与某企业的《二甲醚类橡胶密封材料》规定,在不同配比下的液化石油气二甲醚混合燃料环境中进行橡胶密封圈耐腐蚀性、耐老化和耐低温试验.试验数据显示两种样本的体积变化率与质量变化率都随二甲醚配比的变化而变化,但普通丁腈橡胶的质量变化率随混合燃料配比的变化更明显;耐老化及耐低温试验均合格.相同配比的试剂下,氟橡胶的耐腐蚀性能优于普通丁腈橡胶,因此,氟橡胶安全性能试验符合标准规定,可适用于储存液化石油气二甲醚混合燃料的钢瓶瓶阀的密封材料.

  6. Correction of Ex-core nuclear instrumentation measurement in mechanical shim mode%机械补偿模式下堆外核测测量结果修正

    Institute of Scientific and Technical Information of China (English)

    王瑞; 周赟

    2013-01-01

    Mechanical Shim(MSHIM) mode is used in AP1000 nuclear power plant to control core reactivity and power distribution during load maneuver operations.In MSHIM mode,the motion of MSHIM control rods changes the neutron flux distribution in core,and consequently changes the core power and its distribution.The relationship between the core power and the ex-core Power Range(PR) detector Axial Flux Difference(AFD) is affected significantly,and the current methodology that uses the ex-core PR detector AFD as the input makes too many errors in reactor protection set-point calculation.In this article,the process of measuring axial flux difference by the PR detectors is introduced,and the analysis of effect on AFD in MSHIM mode is discussed.At last,the mathematical modeling of the core power difference and the ex-core PR detector AFD is given to find a method to reduce the error.%AP1000采用机械补偿模式在负荷跟踪过程中对堆芯反应性和功率分布进行控制,在机械补偿模式下,由于机械补偿控制棒的移动,堆芯中子注量率分布发生变化,从而改变了堆芯功率及其分布,作为反应堆保护重要参数的堆外核测测量结果无法满足停堆保护的要求。本文主要介绍了堆外核测堆芯轴向功率偏差的测量方法及其在确定反应堆超温和超功率停堆保护整定值中的作用,分析了采用堆外核测功率量程探测器测量轴向功率偏差在机械补偿模式下受到的影响,提出一种修正测量结果的方法。

  7. Intelligent Shimming for Deep Drawing Processes

    DEFF Research Database (Denmark)

    Tommerup, Søren; Endelt, Benny Ørtoft; Danckert, Joachim

    2011-01-01

    cavities the blank-holder force distribution can be controlled during the punch stroke. By means of a sequence of numerical simulations abrasive wear is imposed to the deep drawing of a rectangular cup. The abrasive wear is modelled by changing the tool surface geometry using an algorithm based...... on the sliding energy density. As the tool surfaces are changed the material draw-in is significantly altered when using conventional open-loop control of the blank-holder force. A feed-back controller is presented which is capable of reducing the draw-in difference to a certain degree. Further a learning...

  8. Intelligent Shimming for Deep Drawing Processes

    DEFF Research Database (Denmark)

    Tommerup, Søren; Endelt, Benny Ørtoft; Danckert, Joachim

    2011-01-01

    cavities the blank-holder force distribution can be controlled during the punch stroke. By means of a sequence of numerical simulations abrasive wear is imposed to the deep drawing of a rectangular cup. The abrasive wear is modelled by changing the tool surface geometry using an algorithm based...... on the sliding energy density. As the tool surfaces are changed the material draw-in is significantly altered when using conventional open-loop control of the blank-holder force. A feed-back controller is presented which is capable of reducing the draw-in difference to a certain degree. Further a learning...

  9. "Erlösung ist, wenn man schulfrei hat!". Erste Ergebnisse einer qualitativ-empirischen Studie zur Erfassung und didaktischen Bearbeitung von Erlösungsvorstellungen 10- bis 14-jähriger SchülerInnen der Sekundarstufe I in Österreich.

    Directory of Open Access Journals (Sweden)

    Thomas Weiß

    2014-07-01

    Full Text Available ENGLISH: The teaching of redemption of mankind through God in Jesus Christ is fundamental to the Christian religion. This article expands on this central topic and presents the first results of a research carried out in schools as part of a current qualitative study about what ideas of redemption ten- to fourteen-year-old students have. The aim of this basic empirical research is to generate views and perspectives on ‚redemption‘ in children and adolescents. A further objective is to develop and integrate didactic tasks for Religious Education as a subject, in order to work on the topic of ‚redemption‘. By doing so, theological reflection should be applied and an alignment within the spheres of life of young people should be provided in lessons at School. DEUTSCH: Die Rede von der Erlösung des Menschen durch Gott in Jesus Christus ist für die christliche Religion fundamental. Der Beitrag widmet sich diesem zentralen Thema und präsentiert die ersten Forschungsergebnisse, die im Rahmen einer aktuellen qualitativen Studie zu Erlösungsvorstellungen von 10- bis 14-jährigen SchülerInnen in Schulen erhoben wurde. Diese grundlagenorientierte empirische Forschungsarbeit hat zum Ziel, kindliche / jugendliche Denk- und Sichtweisen zu ‚Erlösung’ zu generieren und didaktische Aufgaben im Religionsunterricht zu entwickeln und zu implementieren, um das Thema ‚Erlösung’ lebensweltlich orientiert und theologisch reflektiert im schulischen Unterricht bearbeiten zu können.

  10. Mechanical shim mode analysis for large-scale advanced pressurized water reactor%大型先进压水堆堆芯机械补偿控制模式

    Institute of Scientific and Technical Information of China (English)

    王昆鹏; 兰兵; 黄旭阳; 韩向臻; 赵传奇; 潘昕怿

    2017-01-01

    The mechanical shim (MSHIM)operation mode and the load following technology of the large-scale passive ad-vanced PWR core use the relevant design of the AP1000 nuclear power plant as reference,but differ from it due to its higher pow-er and unique control rod loading pattern.Therefore,it is extremely necessary to analyze the applicability of evaluation code for the MSHIM operation mode,the performance of the MSHIM load following operation mode,the characteristics of the start-up and restart processes based on the design of large-scale passive advanced PWR.In this paper,the applicability of MSHIM opera-tion mode for the AP1000 calculation code to the large-scale passive advanced PWR is firstly evaluated based on the analysis of the methodology for the PWR’s MSHIM operation mode and the analysis of the difference between AP1000 and the large-scale pas-sive advanced PWR.Secondly,the typical 100%-70%-100% and 100%-70%-100% load following operation modes of both the initial and the equilibrium cycles are calculated and analyzed based on the neutronics modeling of the large-scale passive advanced PWR core.In addition,the operation capability of the initial start-up and restart processes in MSHIM mode of the initial and e-quilibrium cycles are simulated and analyzed quantitatively.The numerical results show that MSHIM mode has the certain ability for load following in both initial and equilibrium cycles without adj usting the boron concentration,but for start and restart condi-tions it is required to adj ust the concentration of boron.%研究了 AP1000堆芯物理计算程序的计算方法,分析了该程序尤其是机械补偿(MSHIM)控制模式计算功能的理论模型、计算方法及应用范围,对比了大型先进压水堆堆芯设计与 AP1000的差异,评估了AP1000反应堆 MSHIM计算功能在大型先进压水反应堆堆芯 MSHIM计算功能的适用性。基于大型先进压水堆堆芯物理建模,针对大型先进压水反应堆首循环

  11. Nanomedicine in diagnostics

    CERN Document Server

    Rozlosnik, Noemi

    2012-01-01

    Biased Diffusion and Rectified Brownian Motion at the Nanoscale Driving Mobile Sensing Automata for the Early Diagnosis of Endogenous DiseasesDario Narducci and Gianfranco CerofoliniBiotechnology-Utilized Nanopore for Single-Molecule InvestigationJi Wook Shim and Li-Qun GuSelf-assembled Peptide and Protein Nanostructures in DiagnosisJaime Castillo-León, Yuri Belotti, and Winnie E. SvendsenElectrochemical Sensor Systems for MedicineV. V. Shumyantseva, E. V. Suprun, T. V. Bulko, Ya. M. Chalenko, and A. I. ArchakovCon

  12. Infants' Preferential Attention to Sung and Spoken Stimuli

    Science.gov (United States)

    Costa-Giomi, Eugenia; Ilari, Beatriz

    2014-01-01

    Caregivers and early childhood teachers all over the world use singing and speech to elicit and maintain infants' attention. Research comparing infants' preferential attention to music and speech is inconclusive regarding their responses to these two types of auditory stimuli, with one study showing a music bias and another one…

  13. Sung Solecisms: Hip Hop as Non-Prescriptive Pedagogy

    Science.gov (United States)

    Biggs, Cynthia D.

    2011-01-01

    Does the music idiom commonly known as rap music have educational merit? With its harshest critics lambasting it with connotations that equate it with stupidity, gun culture, jail culture, or non-intellectual culture, could there be a pedagogical link after all? Dr. Marc Lamont Hill, Associate Professor of English Education and Anthropology at…

  14. "The word was sung, the word was bound" / Lester Capon

    Index Scriptorium Estoniae

    Capon, Lester, 1951-

    2010-01-01

    4. rahvusvaheline köitekunsti näitus-konkurss "Scripta manent" Eesti Tarbekunsti- ja Disainimuuseumis 9. jaanuarini 2011. Köita tuli Veljo Tormise "Lauldud sõna". Jeff Clementsi, Katinka Keusi (Holland), Lolita Grabauskiene-Tarbunaite (Leedu), Tiina Piisangu, Maila Käose, Ruuda Maarandi töödest

  15. Bowhead whale songs sung by females in Disko Bay, Greenland

    DEFF Research Database (Denmark)

    Tervo, Outi; Christoffersen, Mads; FØrasier, Timothy;

    2011-01-01

    for this species. Bowhead whale song has long been hypothesized to be produced by male whales as a reproductive advertisement; however, no data on the sex of singers has ever been reported. In this study, we determine the sex of singing bowhead whales Balaena mysticetus in Disko Bay, West Greenland, by localizing...... of female bowhead whales may function for mate attraction and represent a novel example of partial courtship role reversal in mammals....

  16. Entweder/Und, Wiederkunft/Erlösung

    OpenAIRE

    Löschenkohl, Birte

    2016-01-01

    Mit merklicher Begeisterung verfasst Walter Benjamin am 6. Januar 1938 einen Brief an Max Horkheimer, in dem er ihm von einem "seltnen Fund" von höchster Bedeutsamkeit berichtet, der seine Arbeit "entscheidend beeinflussen" werde (GB VI, 9). Bei dem Fund handelte es sich um Louis Auguste Blanquis (1805–1881) kosmologische Schrift 'L’Éternité par les astres', verfasst 1871 im Kerker einer Gefängnisburg vor der Küste der Bretagne. Der Autor, einer der umtriebigsten Revolutionäre Frankreichs im ...

  17. "The word was sung, the word was bound" / Lester Capon

    Index Scriptorium Estoniae

    Capon, Lester, 1951-

    2010-01-01

    4. rahvusvaheline köitekunsti näitus-konkurss "Scripta manent" Eesti Tarbekunsti- ja Disainimuuseumis 9. jaanuarini 2011. Köita tuli Veljo Tormise "Lauldud sõna". Jeff Clementsi, Katinka Keusi (Holland), Lolita Grabauskiene-Tarbunaite (Leedu), Tiina Piisangu, Maila Käose, Ruuda Maarandi töödest

  18. Bowhead whale songs sung by females in Disko Bay, Greenland

    DEFF Research Database (Denmark)

    Tervo, Outi; Christoffersen, Mads; FØrasier, Timothy

    2011-01-01

    Song is commonly associated with breeding behaviour with singing primarily occurring during the breeding season and in most species, singers are male. Bowhead whales produce complex song, primarily during the late fall through spring, a period believed to correspond to the mating season for this ......Song is commonly associated with breeding behaviour with singing primarily occurring during the breeding season and in most species, singers are male. Bowhead whales produce complex song, primarily during the late fall through spring, a period believed to correspond to the mating season...... for this species. Bowhead whale song has long been hypothesized to be produced by male whales as a reproductive advertisement; however, no data on the sex of singers has ever been reported. In this study, we determine the sex of singing bowhead whales Balaena mysticetus in Disko Bay, West Greenland, by localizing......% males (n=1)). These data clearly demonstrate that female bowhead whales sing, however more samples are necessary to assess whether male bowhead whales also sing. The suggested functions of female song for other species include territorial defense, mate guarding, coordination of breeding activities...

  19. 在体肝脏3.0T质子MRS匀场与抑水信度研究及相关分析%Reliability and correlation of in vivo heptic shimming of liver and water suppression with 3.0T proton MRS

    Institute of Scientific and Technical Information of China (English)

    徐莉; 梁长虹; 刘再毅; 赵振军; 黄飚; 曾琼新; 萧远球

    2009-01-01

    Objective To assess the reliability of auto-shimming line width (LW) and water suppression rate (WS), and the correlation between them. Methods GE Signa Excite HD 3.0T system and eight-channel torso phased-array coils with PRESS sequence were performed in 38 volunteers. Liver spectra were collected with TR of 1500 ms, TE of 30 ms, VOI of 2 cm×2 cm×2 cm, NSA of 64 times. Spectroscopy routine auto-shimming pre-scanning program was executed and the values of LW and WS were recorded. Then another spectroscopy routine auto-shimming pre-scanning program was performed repeatedly and 38 groups of data were obtained totally. Intra-class correlation coefficients (ICC), coefficient of variation (CV) and significance test were conduced on 38 groups of LW and WS data. Spearman rank correlation analysis was used to assess the correlation of LW and WS. Results ①The ICC of LW and WS was 0.862 and 0.961 (both P<0.0001), respectively, while the value of CV was 0.20, 0.18, 0.09 and 0.08, respectively. Significant difference was not observed; ②The value of correlation coefficient was -0.659, -0.485 (both P<0.0001), respectively. Conclusion ①The reliability is excellent for in vivo liver 3.0T 1H-MRS and WS appears relatively stable; ②Indexes of LW correlate with WS moderately, and it seems the smaller the value of LW is, the easier to achieve higher WS.%目的 探讨在体肝脏3.0T单体素PRESS序列质子MRS自动匀场线宽(LW)和抑水率(WS)的信度及二者的相关性.方法 采用GE Signa Excite HD 3.0T超导MR扫描仪,8通道相控阵线圈.1H-MRS采集参数为TR/TE 1500/30 ms,NSA 64,VOI 2 cm×2 cm×2 cm.波谱常规预扫描,记录LW和WS后进行波谱采集,然后重复执行一次得到另外一组LW及WS数据共计38组.计算两次LW和WS组内相关系数(ICC)、变异系数(CV)及两次重复测量结果之间的显著性,并对LW和WS行等级相关分析. 结果①前后两次波谱常规预扫描LW和WS的ICC分别为0.862、0.961(P均<0

  20. SHIM-Fire Breadboard Instrument Design, Integration, and First Measurements

    Science.gov (United States)

    2005-11-23

    of SHS is described in detail in publications by Harlander et al. [1992, 1994, 2003]. The concept is similar to a Michelson interferometer with the...34 Applied Optics, 41, 1343-1352, 2002. Harlander J.M., F.L. Roesler, C.R. Englert, J.G. Cardon, R.R. Conway, C.M. Brown, J. Wimperis, "Robust monolithic

  1. SHIM-Free Breadboard Instrument Design, Integration, and First Measurements

    Science.gov (United States)

    2005-11-23

    The concept is similar to a Michelson interferometer with the return mirrors replaced by fixed, tilted diffraction gratings. Figure 1 shows the basic...Cardon, R.R. Conway, C.M. Brown, J. Wimperis, "Robust monolithic ultraviolet interferometer for the SHIMMER instrument on STPSat-l," Applied Optics, 42

  2. Korrekturverfahren zur numerischen Lösung nichtlinearer Optimierungsprobleme mittels Methoden der parametrischen Sensitivitätsanalyse

    OpenAIRE

    Nikolayzik, Tim

    2012-01-01

    The nonlinear optimization has becoming of the key technologies of the field of applied mathematics. There are various numbers of applications in different fields of science, e.g. economics, medicine and engineering. Also industry is using mathematical algorithms for solving nonlinear optimization problems. Especially in the aerospace industry nonlinear optimization is frequently used for optimizing trajectories. The aim of this thesis is to extend an existing method for solving nonlinear opt...

  3. Ökologische Autarkie als Beitrag zur Lösung unserer Zukunftsprobleme

    OpenAIRE

    Weller, Wolfgang

    2011-01-01

    Der Mensch als Gast dieser Erde hat ihr Antlitz maßgeblich verändert und dabei ihre Schätze ausgebeutet und auch die Natur geschädigt. Hier wurde inzwischen ein Zustand erreicht, der ein Umdenken erfordert. Im vorliegenden Beitrag wird ein neues Paradigma vorgestellt, welches systemtheoretisch begründet wird und auf die Prinzipien von Autarkie und Ökologie setzt. Zur Verwirklichung dieses Konzepts wird eine Vielzahl von Maßnahmen aufgeführt, deren Darlegung in übersichtlicher Weise erfolgt. ...

  4. Untersuchungen zur Bedeutung anthelminthischer Behandlungen bei der Auslösung von Symptomen einer larvalen Cyathostominose

    OpenAIRE

    Steinbach, Tanja

    2003-01-01

    Im Rahmen dieser Arbeit wird untersucht, ob bei Pferden durch die Gabe von Anthelminthika Symptome einer larvalen Cyathostominose ausgelöst werden können. Im Zentrum des Interesses stehen dabei die Anthelminthika Moxidectin und Fenbendazol, die aufgrund ihrer larviziden Wirksamkeit als Mittel der ersten Wahl für die kausale Therapie und Metaphylaxe der larvalen Cyathostominose angesehen werden. Der Versuch wird an 24 Ponyfohlen durchgeführt, die in die folgenden Gruppen unterteilt werden...

  5. Satellitensysteme zur Lösung des Problems von Asteroiden- und Kometeneinschlägen.

    Science.gov (United States)

    Gritzner, C.

    Einschläge (Impakte) von Asteroiden und Kometen größer 1 km im Durchmesser sind seltene Ereignisse, jedoch mit katastrophalen Folgen für die gesamte irdische Biosphäre. Auch kleinere erdnahe Objekte (NEOs - Near-Earth Objects) können beträchtliche direkte und sekundäre Schäden anrichten. Um solche Impakte zu vermeiden, ist es notwendig, einerseits eine Beobachtungsinfrastruktur zu entwickeln, um alle relevanten NEOs zu entdecken und mit den extrapolierten Bahnparametern eine mögliche Kollision mit der Erde vorherzusagen. Mittels eines Abwehrsystems müßte man dann den NEO auf eine ungefährliche Bahn lenken. In allen Phasen, d.h. von der Suche nach NEOs, über Planung, Test und Einsatz des Abwehrsystems, können oder müssen Satellitensysteme unterschiedlicher Art eingesetzt werden. Konzepte dieser Systeme werden in dieser Arbeit vorgestellt und die mit ihnen verbundenen Probleme diskutiert.

  6. Acoustic Features and Perceptive Cues of Songs and Dialogues in Whistled Speech: Convergences with Sung Speech

    OpenAIRE

    Meyer, Julien

    2007-01-01

    International audience; Whistled speech is a little studied local use of language shaped by several cultures of the world either for distant dialogues or for rendering traditional songs. This practice consists of an emulation of the voice thanks to a simple modulated pitch. It is therefore the result of a transformation of the vocal signal that implies simplifications in the frequency domain. The whistlers adapt their productions to the way each language combines the qualities of height perce...

  7. Leadership Change in North Korean Politics: The Succession to Kim Il Sung

    Science.gov (United States)

    1988-10-01

    became a "guiding star" as early as 1973. In 1977, he was depicted as the "future sun" and the "blessed sunshine ." He has not yet been called the "sun...34 but "future sun" and "blessed sunshine " indicate that he is the future leader, following his father. In recent years, the father and the son have been...image to be destroyed after his death. Rather, he is eager to eternalize the leader-father image through generations. It is therefore prudent to

  8. New leader, new hope for WHO Setting an agenda for Jong-Wook Lee%WHO的新领导和新希望为李钟郁制定一个工作纲领

    Institute of Scientific and Technical Information of China (English)

    Gavin Yamey; Kamran Abbasi

    2003-01-01

    @@ 90年代中期,世界卫生组织(WHO)似乎难以逃脱两种命运--陷入腐败和低效的官僚主义泥潭1或是走向死亡2.然而两者都没有发生.相反,1998年7月成为WHO总干事的布伦特兰(Gro Harlem Brundtland)重振了WHO在全球卫生领域的声望3.

  9. On Network Coded Filesystem Shim: Over-the-top Multipath Multi-Source Made Easy

    DEFF Research Database (Denmark)

    Sørensen, Chres Wiant; Roetter, Daniel Enrique Lucani; Médard, Muriel

    2017-01-01

    benefits to any application in a computer. However, incorporating new protocols to the Internet is a challenging and slow process. Second, deploying coding at the application layer, which forces each application to implement network coding. This paper proposes an alternative approach through the use...

  10. Problemes de traduction dans le domaine de la poesie chantee (Problems of Translation in the Area of Sung Poetry)

    Science.gov (United States)

    Grandmont, Suzanne de

    1978-01-01

    In the translation of songs, to the usual problems of rendering meaning, symbols and imagery are added the exigencies of cadence, rhythm, tempo and tonic accent. The process is illustrated by an account of the rendering in French of the musical comedy, "The Fantasticks." (Text is in French.) (AMH)

  11. Umwandlung von Kohlendioxid mit Übergangsmetall-Homogenkatalysatoren: eine molekulare Lösung für ein globales Problem?

    KAUST Repository

    Cokoja, Mirza

    2011-08-29

    A plethora of methods have been developed over the years so that carbon dioxide can be used as a reactant in organic synthesis. Given the abundance of this compound, its utilization in synthetic chemistry, particularly on an industrial scale, is still at a rather low level. In the last 35 years, considerable research has been performed to find catalytic routes to transform CO2 into carboxylic acids, esters, lactones, and polymers in an economic way. This Review presents an overview of the available homogeneous catalytic routes that use carbon dioxide as a C1 carbon source for the synthesis of industrial products as well as fine chemicals.

  12. Konflikt und Konfliktlösung in Guatemala – Die Verwirklichung der Rechte indigener Frauen im rechtspluralistischen Raum

    NARCIS (Netherlands)

    A. Titze (Anja)

    2008-01-01

    textabstractIm 20. Jahrhundert erlebte die Menschheit die Gräueltaten von zwei Weltkriegen und zahllosen Bürgerkriegen, die allesamt unermessliches Leid brachten. Auch Guatemala ist insoweit ein trauriges Beispiel. Der Bürgerkrieg, der dort in der Zeit des Kalten Krieges wütete und erst 1996 endete,

  13. Welche Bodenzusätze helfen bei der Lösung von Problemen mit Feldaufgang in Spinat?

    OpenAIRE

    Meyer, Audrey; Fuchs, Jacques G.; Schärer, Hansjakob

    2013-01-01

    Damping-off of spinach, caused by soil-borne pathogens, is one of the most serious problems in organic spinach production. To overcome these problems soil amendments based on specific strains of micro-organisms or based on organic material are proposed. In pot experiments under controlled conditions 14 microbial strains and six organic soil amendments were tested on their ability to suppress soil borne diseases and to improve plant stand establishment. In a subsequent field experiment with th...

  14. Development of a chitosan based double layer-coated tablet as a platform for colon-specific drug delivery

    Directory of Open Access Journals (Sweden)

    Kim MS

    2016-12-01

    Full Text Available Min Soo Kim,1,* Dong Woo Yeom,1,* Sung Rae Kim,1 Ho Yub Yoon,1 Chang Hyun Kim,1 Ho Yong Son,1 Jin Han Kim,1 Sangkil Lee,2 Young Wook Choi1 1College of Pharmacy, Chung-Ang University, Seoul, 2College of Pharmacy, Keimyung University, Daegu, South Korea *These authors contributed equally to this work Abstract: A double layer-coated colon-specific drug delivery system (DL-CDDS was developed, which consisted of chitosan (CTN based polymeric subcoating of the core tablet containing citric acid for microclimate acidification, followed by an enteric coating. The polymeric composition ratio of Eudragit E100 and ethyl cellulose and amount of subcoating were optimized using a two-level factorial design method. Drug-release characteristics in terms of dissolution efficiency and controlled-release duration were evaluated in various dissolution media, such as simulated colonic fluid in the presence or absence of CTNase. Microflora activation and a stepwise mechanism for drug release were postulated. Consequently, the optimized DL-CDDS showed drug release in a controlled manner by inhibiting drug release in the stomach and intestine, but releasing the drug gradually in the colon (approximately 40% at 10 hours and 92% at 24 hours in CTNase-supplemented simulated colonic fluid, indicating its feasibility as a novel platform for CDD. Keywords: chitosan, colon-specific delivery, acidification, microflora, factorial design, controlled release

  15. Cationic PLGA/Eudragit RL nanoparticles for increasing retention time in synovial cavity after intra-articular injection in knee joint

    Directory of Open Access Journals (Sweden)

    Kim SR

    2015-08-01

    Full Text Available Sung Rae Kim,1 Myoung Jin Ho,2 Eugene Lee,3 Joon Woo Lee,3 Young Wook Choi,1 Myung Joo Kang21College of Pharmacy, Chung-Ang University, Dongjak-gu, Seoul, 2College of Pharmacy, Dankook University, Dongnam-gu, Cheonan, Chungnam, 3Department of Radiology, Seoul National University Bundang Hospital, Bundang-gu, Seongnam, Gyeonggi-do, South KoreaAbstract: Positively surface-charged poly(lactide-co-glycolide (PLGA/Eudragit RL nanoparticles (NPs were designed to increase retention time and sustain release profile in joints after intra-articular injection, by forming micrometer-sized electrostatic aggregates with hyaluronic acid, an endogenous anionic polysaccharide found in high amounts in synovial fluid. The cationic NPs consisting of PLGA, Eudragit RL, and polyvinyl alcohol were fabricated by solvent evaporation technique. The NPs were 170.1 nm in size, with a zeta potential of 21.3 mV in phosphate-buffered saline. Hyperspectral imaging (CytoViva® revealed the formation of the micrometer-sized filamentous aggregates upon admixing, due to electrostatic interaction between NPs and the polysaccharides. NPs loaded with a fluorescent probe (1,1'-dioctadecyl-3,3,3',3' tetramethylindotricarbocyanine iodide, DiR displayed a significantly improved retention time in the knee joint, with over 50% preservation of the fluorescent signal 28 days after injection. When DiR solution was injected intra-articularly, the fluorescence levels rapidly decreased to 30% of the initial concentration within 3 days in mice. From these findings, we suggest that PLGA-based cationic NPs could be a promising tool for prolonged delivery of therapeutic agents in joints selectively.Keywords: PLGA, Eudragit RL, hyaluronic acid, cationic nanoparticles, intra-articular injection, electrostatic interaction

  16. Die Einverleibung Holsteins im Jahre 1806 und die dänische Reaktion auf die Auflösung des Alten Reiches

    DEFF Research Database (Denmark)

    Bregnsbo, Michael

    2008-01-01

    Den danske statsledelses integrationspolitik over for hertugdømmet Holsten, der havde hørt under det Hellige Romerske Rige af Tysk Nation efter at dette rige var blevet opløst i 1806. Der argumenteres for, at integrationsbestræbelserne ikke udelukkende var dansk-nationale, men også udtryk for en ...

  17. Molekülinterne Dipolorientierung und dielektrische Absorption in verdünnter Lösung bei Mikro-und Submillimeterwellen. V.Acetyl-Verbindungen

    Science.gov (United States)

    Klages, Gerhard

    1989-09-01

    The dielectric loss of sixteen molecules, eleven with the acetyle group in aromatic bonds and five in aliphatic bonds, has been measured in very dilute solutions of cyclohexene at 20 °C. Five of these molecules are investigated in decalene solutions, too. The measurements have been made at wavenumbers in the range 0.08 to 140 cm -1 above 8 cm -1 making use of a pumped molecular laser. They are supplemented by the data of a Fourier transform spectrometer up to 300 cm -1. All microwave spectra of loss factor ɛ″ are analysed in terms of three absorption areas using the two variable Mori formalism. On the other hand, Lorentz curves are fitted to the FIR absorption spectra of α(v¯). The fast relaxation process of the aliphatic compounds is suggested to be due to intramolecular reorientation of the acetyle group itself, since in acetyle cyclohexene the remaining part of the molecule is rigid. To the contrary, the acetyle group is not able to reorientate swiftly, if bounded to aromatic rings. Presumably, it is fixed by mesomeric interaction with the dipole in the plain of the ring. However, 2-methyl acetophenone and 1-acetyle naphthone show some quick dipole reorientation, which coincides with a steric hindrance of the group in entering the plain of the ring.

  18. Labour Costs for Inventory Control Less Expensive than Repurchasing. A Review of: Sung, J. S., Whisler, J. A., & Sung, N. (2009. A cost-benefit analysis of a collections inventory project: A statistical analysis of inventory data from a medium-sized academic library. Journal of Academic Librarianship, 35(4, 314-323.

    Directory of Open Access Journals (Sweden)

    Laura Newton Miller

    2010-09-01

    Full Text Available Objective – To describe an inventory system that was created within the library and to show the cost-effectiveness of using the inventory system compared to the price of reacquiring mis-shelved books.Design – Bibliometric study and cost-benefit analysis.Setting – Medium-sized academic library in a rural community of the United States.Subjects – Approximately 300,000 books from LC classifications D through H, N, P and Q, representing two thirds of the library’s entire monograph collection.Methods – The library created its own electronic inventory and shelf-reading program, using a laptop computer equipped with a hand-held scanner, to scan barcodes in the stacks. Library staff used the Microsoft Access database to update two files containing a shelf-list and an active-status list while the books were scanned. The program alerted the worker if books found had an active status (i.e., Missing, Renewed, Overdue, Charged, were not in the correct order, or were not in the system. Each transaction created a log which contained a time stamp (to the second, the call number and the barcode number. It also took note of scanning errors, books that were out of order, and books that were not on a shelf-list. After a complete section was examined, a list was produced to reveal the distance of mis-shelved books from their correct location and the amount of time between each scan. The researchers used statistical analysis (using SPSS 15.0 to measure scan speed for each scan, mis-shelving rate and error distance of each mis-shelved book. In order to analyze the cost of labour to replace a book versus the cost of inventorying, the researchers estimated the salary costs of staff members involved in selection, acquisition and cataloguing. The library spent $440,000 USD in labour costs to purchase 15,000 monographs in one fiscal year (approximately $30.00 USD in labour costs per book. They multiplied this by 5300 books that were found to be “badly” mis-shelved (found beyond 25 books away from the proper position. Labour fees were used to determine costs of inventorying by calculating average scanning speed and cost per hour to pay someone to scan the entire half-million monograph collection.Main Results – It took approximately 707 hours to scan 305,000 monographs. The average (mode calculation for scans was 5 seconds for 80% of the barcodes, with an average (mean of 8.35 seconds between scans. The longest average (mean time for scanning barcodes was in the N section, followed by G, H, P, Q, D, E and F. A total of 291 books were found on the shelves with an “active” status (i.e., Charged (4, Overdue (7, Renewed (4, In Transit (24, and Missing (228. Twenty-four books with the status “Miscellaneous” (i.e., At Bindery, Call Slip, Cataloguing Review, Damaged, and Mending were also found on the shelves. Of the 15 active books in the categories “Charged”, “Overdue” and “Renewed”, ten were found in the proper position on the shelf. Of the 228 “Missing” books, 30% were scanned in the correct location, 10% were found 26 to 100 books away, and half were located over 100 books from their proper location. In addition to the books already marked as “Missing” in the catalogue, there were 516 books (.17% of the entire scanned section still not found on the shelf after three searches over a period of 6 months. Of the 291 active status books found on the shelves, 52% were reused as of July 2008. (The inventory was completed at the end of 2006. Over 36% of books mis-shelved further than 25 books from their correct location were reused. However, among all books scanned, only 17% were reused during the same time period. The researchers noted that inconsistencies between the call number as shown on the book label and how it appeared in the catalogue occurred 565 times. Of these discrepancies, 40% of the labels resulted in books being misplaced ten or fewer books away, 10% misplaced between 10 and 100 books away, and 35% misplaced more than 100 books away from the correct position. In general, 82% of mis-shelved books were found within 1 to 25 books away from their correct location. By calculating that 5300 books were mis-shelved beyond 25 books away from their proper position, labour costs were estimated to be at least $159,000 USD (5300 x $30.00 USD per book in labour costs. Costs for interlibrary loan were calculated at approximately $30.00 USD per transaction, and patron’s time wasted trying to locate misplaced books was estimated at 30 minutes per book. This was much more than the labour costs associated with scanning books, which at an average speed of 8 seconds per book and $10.00 US per hour for scanning worked out to be 2.2 cents per book, or $11,000 USD to scan the entire half-million monograph collection.Conclusion – The results appear to reveal that the labour costs for inventory control are less expensive than repurchasing or borrowing the same number of books.

  19. Labour Costs for Inventory Control Less Expensive than Repurchasing. A Review of: Sung, J. S., Whisler, J. A., & Sung, N. (2009). A cost-benefit analysis of a collections inventory project: A statistical analysis of inventory data from a medium-sized academic library. Journal of Academic Librarianship, 35(4), 314-323.

    OpenAIRE

    Laura Newton Miller

    2010-01-01

    Objective – To describe an inventory system that was created within the library and to show the cost-effectiveness of using the inventory system compared to the price of reacquiring mis-shelved books.Design – Bibliometric study and cost-benefit analysis.Setting – Medium-sized academic library in a rural community of the United States.Subjects – Approximately 300,000 books from LC classifications D through H, N, P and Q, representing two thirds of the library’s entire monograph collection.Meth...

  20. A radiological study on lumbar spondylolisthesis with intact neural arch

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Myung Ju; Suh, Young Jun; Joe, Seong Jeh; Yoon, Jong Sup [Han-Gang Sung-Shim Hospital, Seoul (Korea, Republic of)

    1980-12-15

    The purpose of this paper is to evaluate and analyze the radiological findings of 13 cases of lumbar spondylolisthesis with intact neural arch at Han-Gang Sung- Shim Hospital during period from Jan. 1975 to June 1980. 1. The age distribution of the patients varied from 31 to 83 years old. The average of the age was 53 years old. 12 patients were female and only one patient was male. 2. All cases revealed anterior slipping of the L4 body on the L5 body, of which degree was classified by Meyerding's method, first degree in 12 patients and second degree in one patient. 3. The angle between the pedicle and inferior articular facet of affected vertebra was measured by Junghann's method. The average of angle was 123 degree. 4. Of 13 cases, 2 cases who had neural compression caused by dislocation of the vertebral bodies and intrusion of lamina and arthritic facets into stenotic spinal canal treated by laminar decompression including foraminotomy. Good results were obtained. 5. The secondary degenerative change of the vertebra was considered to be the cause of the spondylolisthesis with intact neural arch.

  1. Traditsioonist ja uuendusest korea modernkunstis / Katrin Kivimaa

    Index Scriptorium Estoniae

    Kivimaa, Katrin, 1969-

    2005-01-01

    Souli galeriides ja muuseumides valitseb eeldatud kõrgtehnoloogilise kunsti asemel maalikunst. Pikemalt naiskunstnik Wook-kyung Choi (1940-1985) ja Jong-gu Lee näitustest ning soo- ja naisuuringute kongressist "Women's World 2005"

  2. Traditsioonist ja uuendusest korea modernkunstis / Katrin Kivimaa

    Index Scriptorium Estoniae

    Kivimaa, Katrin, 1969-

    2005-01-01

    Souli galeriides ja muuseumides valitseb eeldatud kõrgtehnoloogilise kunsti asemel maalikunst. Pikemalt naiskunstnik Wook-kyung Choi (1940-1985) ja Jong-gu Lee näitustest ning soo- ja naisuuringute kongressist "Women's World 2005"

  3. Increased localized delivery of piroxicam by cationic nanoparticles after intra-articular injection

    Directory of Open Access Journals (Sweden)

    Kim SR

    2016-11-01

    Full Text Available Sung Rae Kim,1 Myoung Jin Ho,2 Sang Hyun Kim,1 Ha Ra Cho,2 Han Sol Kim,2 Yong Seok Choi,2 Young Wook Choi,1 Myung Joo Kang2 1Division of Pharmaceutical Sciences, College of Pharmacy, Chung-Ang University, Seoul, 2College of Pharmacy, Dankook University, Cheonan, Chungnam, South Korea Abstract: Piroxicam (PRX, a potent nonsteroidal anti-inflammatory drug, is prescribed to relieve postoperative and/or chronic joint pain. However, its oral administration often results in serious gastrointestinal adverse effects including duodenal ulceration. Thus, a novel cationic nanoparticle (NP was explored to minimize the systemic exposure and increase the retention time of PRX in the joint after intra-articular (IA injection, by forming micrometer-sized electrostatic clusters with endogenous hyaluronic acid (HA in the synovial cavity. PRX-loaded NPs consisting of poly(lactic-co-glycolic acid, Eudragit RL, and polyvinyl alcohol were constructed with the following characteristics: particle size of 220 nm, zeta potential of 11.5 mV in phosphate-buffered saline, and loading amount of 4.0% (w/w of PRX. In optical and hyperspectral observations, the cationic NPs formed more than 50 µm-sized aggregates with HA, which was larger than the intercellular gaps between synoviocytes. In an in vivo pharmacokinetic study in rats, area under the plasma concentration–time curve (AUC0–24 h and maximum plasma concentration (Cmax of PRX after IA injection of the cationic NPs were <70% (P<0.05 and 60% (P<0.05, respectively, compared to those obtained from drug solution. Moreover, the drug concentration in joint tissue 24 h after dosing with the cationic NPs was 3.2-fold (P<0.05 and 1.8-fold (P<0.05 higher than that from drug solution and neutrally charged NPs, respectively. Therefore, we recommend the IA cationic NP therapy as an effective alternative to traditional oral therapy with PRX, as it increases drug retention selectively in the joint. Keywords: piroxicam

  4. Design and in vivo evaluation of oxycodone once-a-day controlled-release tablets

    Directory of Open Access Journals (Sweden)

    Kim JY

    2015-01-01

    Full Text Available Ju-Young Kim,1,* Sung-Hoon Lee,2,3,* Chun-Woong Park,4 Yun-Seok Rhee,5 Dong-Wook Kim,6 Junsang Park,3 Moonseok Lee,3 Jeong-Woong Seo,2 Eun-Seok Park2 1College of Pharmacy, Woosuk University, Wanju-gun, Republic of Korea; 2School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea; 3GL Pharmtech, Seongnam, Republic of Korea; 4College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea; 5College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, Republic of Korea; 6Department of Pharmaceutical Engineering, Cheongju University, Cheongju, Republic of Korea *These authors contributed equally to this work Abstract: The aim of present study was to design oxycodone once-a-day controlled-release (CR tablets and to perform in vitro/in vivo characterizations. Release profiles to achieve desired plasma concentration versus time curves were established by using simulation software and reported pharmacokinetic parameters of the drug. Hydroxypropyl methylcellulose (HPMC 100,000 mPa·s was used as a release modifier because the polymer was found to be resistant to changes in conditions of the release study, including rotation speed of paddle and ion strength. The burst release of the drug from the CR tablets could be suppressed by applying an additional HPMC layer as a physical barrier. Finally, the oxycodone once-a-day tablet was comprised of two layers, an inert HPMC layer and a CR layer containing drug and HPMC. Commercial products, either 10 mg bis in die (bid [twice a day] or once-a-day CR tablets (20 mg were administered to healthy volunteers, and calculated pharmacokinetic parameters indicated bioequivalence of the two different treatments. The findings of the present study emphasize the potential of oxycodone once-a-day CR tablets for improved patient compliance, safety, and efficacy, which could help researchers to develop new CR dosage forms of oxycodone. Keywords

  5. One-step detection of circulating tumor cells in ovarian cancer using enhanced fluorescent silica nanoparticles

    Directory of Open Access Journals (Sweden)

    Kim JH

    2013-06-01

    Full Text Available Jin Hyun Kim,1,* Hyun Hoon Chung,2,* Min Sook Jeong,1 Mi Ryoung Song,1 Keon Wook Kang,3,4 Jun Sung Kim1 1R&D Center, Biterials Co, Ltd, Seoul, Republic of Korea; 2Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea; 3Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 4Cancer Research Institute, Seoul National University, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: Ovarian cancer is the fifth-leading cause of cancer-related deaths among women as a result of late diagnosis. For survival rates to improve, more sensitive and specific methods for earlier detection of ovarian cancer are needed. This study presents the development of rapid and specific one-step circulating tumor cell (CTC detection using flow cytometry in a whole-blood sample with fluorescent silica nanoparticles. We prepared magnetic nanoparticle (MNP-SiO2(rhodamine B isothiocyanate [RITC] (MNP-SiO2[RITC] incorporating organic dyes [RITC, λmax(ex/em = 543/580 nm] in the silica shell. We then controlled the amount of organic dye in the silica shell of MNP-SiO2(RITC for increased fluorescence intensity to overcome the autofluorescence of whole blood and increase the sensitivity of CTC detection in whole blood. Next, we modified the surface function group of MNP-SiO2(RITC from –OH to polyethylene glycol (PEG/COOH and conjugated a mucin 1 cell surface-associated (MUC1 antibody on the surface of MNP-SiO2(RITC for CTC detection. To study the specific targeting efficiency of MUC1-MNP-SiO2(RITC, we used immunocytochemistry with a MUC1-positive human ovarian cancer cell line and a negative human embryonic kidney cell line. This technology was capable of detecting 100 ovarian cancer cells in 50 µL of whole blood. In conclusion, we developed a one-step CTC detection technology in ovarian cancer based on multifunctional silica nanoparticles

  6. Zinc oxide nanoparticles: a 90-day repeated-dose dermal toxicity study in rats

    Directory of Open Access Journals (Sweden)

    Ryu HJ

    2014-12-01

    Full Text Available Hwa Jung Ryu,1,* Mu Yeb Seo,2,* Sung Kyu Jung,1 Eun Ho Maeng,2 Seung-Young Lee,2 Dong-Hyouk Jang,2 Taek-Jin Lee,2 Ki-Yeon Jo,2 Yu-Ri Kim,3 Kyu-Bong Cho,4 Meyoung-Kon Kim,3 Beom Jun Lee,5 Sang Wook Son1 1Department of Dermatology, Korea University College of Medicine, Seoul, 2Korea Testing and Research Institute, Gyunggido, 3Department of Biochemistry and Molecular Biology, Korea University College of Medicine, Seoul, 4Department of Clinical Laboratory Science, Shinheung College, Uijeongbu, 5College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea *These authors contributed equally to this work and both should be considered first authors Abstract: Zinc oxide (ZnO works as a long-lasting, broad-spectrum physical sunblock, and can prevent skin cancer, sunburn, and photoaging. Nanosized ZnO particles are used often in sunscreens due to consumer preference over larger sizes, which appear opaque when dermally applied. Although the US Food and Drug Administration approved the use of nanoparticles (NPs in sunscreens in 1999, there are ongoing safety concerns. The aim of this study was to evaluate the subchronic toxicity of ZnO NPs after dermal application according to the Organization for Economic Cooperation and Development Test Guidelines 411 using Good Laboratory Practice. Sprague Dawley rats were randomly divided into eight (one control, one vehicle control, three experimental, and three recovery groups. Different concentrations of ZnO NPs were dermally applied to the rats in the experimental groups for 90 days. Clinical observations as well as weight and food consumption were measured and recorded daily. Hematology and biochemistry parameters were determined. Gross pathologic and histopathologic examinations were performed on selected tissues from all animals. Analyses of tissue were undertaken to determine target organ tissue distribution. There was no increased mortality in the experimental group. Although there

  7. The association between combined non-cystic fibrosis bronchiectasis and lung cancer in patients with chronic obstructive lung disease

    Directory of Open Access Journals (Sweden)

    Kim YW

    2015-05-01

    Full Text Available Yeon Wook Kim,1 Kwang-Nam Jin,2 Eun Young Heo,3 Sung Soo Park,3 Hee Soon Chung,3 Deog Kyeom Kim31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Department of Radiology, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of KoreaBackground: Whereas the epidemiological association between lung cancer and chronic obstructive pulmonary disease (COPD, a chronic inflammatory respiratory disease, is well known, limited studies have examined the association between lung cancer and non-cystic fibrosis bronchiectasis, a representative chronic airway inflammatory disease. This study evaluated the association between bronchiectasis and lung cancer in patients with COPD.Methods: A matched case–control study was conducted in a referral hospital in South Korea. Among COPD patients with moderate to very severe airflow limitation (forced expiratory volume in one second/forced vital capacity <0.7 and forced expiratory volume in one second ≤70% [% predicted] who underwent chest computed tomography (CT between January 1, 2010 and May 30, 2013, patients with lung cancer and controls matched for age, sex, and smoking history were selected. The risk of lung cancer was assessed according to the presence of underlying bronchiectasis confirmed by chest CT.Results: The study enrolled 99 cases and 198 controls. Combined bronchiectasis on chest CT was inversely associated with the risk of lung cancer compared with controls (odds ratio [OR] 0.25, 95% confidence interval [CI] 0.12–0.52, P<0.001. Significant associations were found in

  8. Toxicity of colloidal silica nanoparticles administered orally for 90 days in rats

    Directory of Open Access Journals (Sweden)

    Kim YR

    2014-12-01

    Full Text Available Yu-Ri Kim,1,* Seung-Young Lee,3,* Eun Jeong Lee,1 Sung Ha Park,4 Nak-won Seong,3 Heung-Sik Seo,3 Sung-Sup Shin,3 Seon-Ju Kim,3 Eun-Ho Meang,3 Myeong-Kyu Park,3 Min-Seok Kim,3 Cheol-Su Kim,5 Soo-Ki Kim,5 Sang Wook Son,2 Young Rok Seo,6 Boo Hyon Kang,7 Beom Seok Han,8 Seong Soo A An,9 Beom-Jun Lee,10 Meyoung-Kon Kim1 1Department of Biochemistry and Molecular Biology, 2Department of Dermatology, Korea University Medical School and College, 3General Toxicology Team, Korea Testing and Research Institute, Seoul, Republic of Korea; 4Department of Biochemistry, University of Bath, Bath, UK; 5Department of Microbiology, Wonju College of Medicine, Yonsei University, Gangwon, 6Department of Life Science, Institute of Environmental Medicine for Green Chemistry, Dongguk University, Seoul, 7Nonclinical Research Institute, Chemon Inc, Gyeonggi, 8Toxicological Research Center, Hoseo University, Chungnam, 9Department of Bionanotechnology, Gachon University, Gyeonggi, 10College of Veterinary Medicine, Chungbuk National University, Chungbuk, Republic of Korea *These authors contributed equally to this work Abstract: This study was undertaken to investigate the potential toxicity and establish the no observed adverse effect level (NOAEL and target organ(s of negatively charged colloidal silica particles of different sizes, ie, SiO2EN,20(- (20 nm or SiO2EN,100(- (100 nm, administered by gavage in Sprague-Dawley rats. After verification of the physicochemical properties of the SiO2 particles to be tested, a preliminary dose range-finding study and 90-day repeated dose study were conducted according to the Organisation for Economic Cooperation and Development test guideline. Based on the results of the 14-day dose range-finding study, a high dose was determined to be 2,000 mg/kg, and middle and low doses were set at 1,000 and 500 mg/kg, respectively. In the 90-day toxicity study, there were no animal deaths in relation to administration of SiO2 particles of

  9. Spektralphotometrische Bestimmung des pflanzenverfügbaren Nitrats in der Bodenlösung : Entwicklung einer in-situ Messmethode zur Optimierung der Fertigation im intensiven Gemüsebau

    OpenAIRE

    Mayer, Stephan

    2015-01-01

    Bei vielen Sonderkulturen, hauptsächlich aber im intensiven Gemüsebau, kann sich bereits ein geringer Mangel an Stickstoff stark qualitäts- und ertragsmindernd auswirken. Daher wird besonders dort häufig im Überschuss gedüngt. Dies bedeutet, im Vergleich zu dem tatsächlichen N-Bedarf einer Kultur, oft einen erhöhten Aufwand an Dünger, was zu starken N-Verlusten durch Auswaschung führen kann. Stark nitratbelastete Grund- und Oberflächengewässer sind vielerorts die Folge. Eine in-situ Metho...

  10. A multicenter study of mid urethral sung procedures in treatment of female stress urinary incontinence%中段尿道吊带术治疗女性压力性尿失禁的多中心研究

    Institute of Scientific and Technical Information of China (English)

    杜广辉; 陈忠; 胡卫锋; 章传华; 张景宇; 祝子清; 叶章群

    2008-01-01

    目的 探讨中段尿道吊带术治疗女性压力性尿失禁的临床疗效、手术指征和并发症的处理.方法 单纯压力性尿失禁的患者304例和混合性尿失禁的患者8例,均为女性,纳入本研究.其中接受TVT吊带术134例,TVTO吊带术167例,Monarc吊带术11例.围手术期评估包括:手术时间、出血量、术中术后并发症.手术效果分为治愈、显效、无效.在患者出院时、术后3个月、术后每年评价疗效和并发症.结果 TVT组手术时间(18.5±9.6)min和出血量(32.2±12.6)ml多于TVTO组(11.5±3.1)min,(12.8±8.5)ml和Monarc组(11.1±2.6)min,(12.3±3.5)ml(P0.05).单纯压力性尿失禁患者治愈率(95.7% )显著高于混合性尿失禁患者(37.5% )(P<0.01).3种术式的总并发症发生率差异无统计学意义,但膀胱损伤仅发生在TVT组,闭孔神经损伤和阴道损伤仅发生在TVTO组.术后排尿困难和尿潴留是中段尿道吊带术的最常见并发症.结论 经耻骨上途径(TVT)和经闭孔途径(TVTO、Monarc)中段尿道吊带术治疗压力性尿失禁均具有手术简单、微创、中长期疗效好、并发症少等优点.%Objective To investigate the clinical efficacy,surgical indications and postoperative complications of mid urethral sling procedures in treatment of female stress urinary incontinence.Methods A muhicenter clinical trial was conducted from April 2002 to April 2008 in five hospitals,304 cases of genuine stress urinary incontinence and 8 cases of mixed incontinence were included.TVT procedures were carried out in 134 patients.TVTO procedures in 167 patients,Monare procedures in 11 patients.Perioperative evaluations included: operating time, bleeding volume, and perioperative complications.Operative efficacy was classified into three categories:cure,improved and failure and evaluated before discharge,3 months after surgery and then every year. Results TVT group had longer operating time [(18.5±9.6)min]and more bleeding volume[(32.2±12.6)ml]than those in TVTO group[(11.5 ±3.1)min,(12.8±8.5)m]and in Monarc group[(11.1±2.6)min,(12.3±3.5)ml]with P<0.05.Monarc and TVTO procedures had higher cure rates and impmve rates comparing with TVT,but the differences were of no significance.The cure rate(95.7% )in patients with genuine stress incontinence were significantly higher than that in patients with mixed incontinence(37.5% ).No significant differences oftotal intra- and postoperative complications were noted for all of the three procedures.However,bhdder injury tended to occuned in TVT group and obturator nerve injury and vaginal injury tended to occurre in TVTO group.Transient voiding dysfunction and urinary retention were the most common complications.Conclusions Mid urethral sling procedures have excellent clinical outcomes in the treatment of female stress urinary incontinence.

  11. Bổ sung giun quế (Perionyx excavatus) cho gà thịt (Hồ x Lương Phượng) từ 4 - 10 tuần tuổi

    OpenAIRE

    Vu, Dinh Ton; Han Quang, Hanh; Nguyen, Dinh Linh; Dang, Vu Binh

    2009-01-01

    The present study was aimed to assess the effect of different levels of red worm (Perionyx excavatus) supplemented to the diet on growth performance and meat quality of broilers. An experiment was conducted on broilers (Ho x Luong Phuong) of 4 - 10 weeks old according to a completely randomized design with one unsupplemented group (control) and three supplemented groups corresponding to 3 worm levels in the diet, viz. 1%, 1.5%, and 2% on a dry matter basis. Results showed that th...

  12. A model for estimating body shape biological age based on clinical parameters associated with body composition

    Directory of Open Access Journals (Sweden)

    Bae CY

    2012-12-01

    Full Text Available Chul-Young Bae,1 Young Gon Kang,2 Young-Sung Suh,3 Jee Hye Han,4 Sung-Soo Kim,5 Kyung Won Shim61MediAge Research Center, Seoul, Korea; 2Chaum Power Aging Center, College of Medicine, CHA University, Seoul, Korea; 3Health Promotion Center, Keimyung University Dongsam Medical Center, Daegu, Korea; 4Department of Family Medicine, College of Medicine, Eulji University, Seoul, Korea; 5Department of Family Medicine, College of Medicine, Chungnam National University, Daejeon, Korea; 6Department of Family Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University, Seoul, KoreaBackground: To date, no studies have attempted to estimate body shape biological age using clinical parameters associated with body composition for the purposes of examining a person's body shape based on their age.Objective: We examined the relations between clinical parameters associated with body composition and chronological age, and proposed a model for estimating the body shape biological age.Methods: The study was conducted in 243,778 subjects aged between 20 and 90 years who received a general medical checkup at health promotion centers at university and community hospitals in Korea from 2004 to 2011.Results: In men, the clinical parameters with the highest correlation to age included the waist-to-hip ratio (r = 0.786, P < 0.001, hip circumference (r = −0.448, P < 0.001, and height (r = −0.377, P < 0.001. In women, the clinical parameters with the highest correlation to age include the waist-to-hip ratio (r = 0.859, P < 0.001, waist circumference (r = 0.580, P < 0.001, and hip circumference (r = 0.520, P < 0.001. To estimate the optimal body shape biological age based on clinical parameters associated with body composition, we performed a multiple regression analysis. In a model estimating the body shape biological age, the coefficient of determination (R2 was 0.71 in men and 0.76 in women.Conclusion: Our model for estimating body shape biological age

  13. Efficacy and safety of fixed-dose combination therapy with olmesartan medoxomil and rosuvastatin in Korean patients with mild to moderate hypertension and dyslipidemia: an 8-week, multicenter, randomized, double-blind, factorial-design study (OLSTA-D RCT: OLmesartan rosuvaSTAtin from Daewoong

    Directory of Open Access Journals (Sweden)

    Park JS

    2016-08-01

    Full Text Available Jin-Sun Park,1,* Joon-Han Shin,1,* Taek-Jong Hong,2 Hong-Seog Seo,3 Wan-Joo Shim,4 Sang-Hong Baek,5 Jin-Ok Jeong,6 Youngkeun Ahn,7 Woong-Chol Kang,8 Young-Hak Kim,9 Sang-Hyun Kim,10 Min-Su Hyon,11 Dong-Hoon Choi,12 Chang-Wook Nam,13 Tae-Ho Park,14 Sang-Chol Lee,15 Hyo-Soo Kim16 1Department of Cardiology, Ajou University School of Medicine, Suwon, 2Division of Cardiology, Pusan National University Hospital, Busan, 3Division of Cardiology, Korea University Guro Hospital, Korea University College of Medicine, 4Division of Cardiology, Korea University Anam Hospital, 5Cardiovascular Division, Catholic University of Korea, Seoul St Mary’s Hospital, Seoul, 6Division of Cardiology, Chungnam National University Hospital, Daejeon, 7Division of Cardiology, Chonnam National University Hospital, Gwangju, 8Division of Cardiology, Gachon University Gil Hospital, Incheon, 9Division of Cardiology, Asan Medical Center, College of Medicine, University of Ulsan, 10Division of Cardiology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, 11Division of Cardiology, Soonchunhyang University Hospital, 12Division of Cardiology, Yonsei University Severance Hospital, Seoul, 13Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, 14Division of Cardiology, Dong-A University Hospital, Busan, 15Cardiovascular Imaging Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 16Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea *These authors contributed equally to this work Abstract: The pill burden of patients with hypertension and dyslipidemia can result in poor medication compliance. This study aimed to evaluate the efficacy and safety of fixed-dose combination (FDC therapy with olmesartan medoxomil (40 mg and rosuvastatin (20 mg in Korean patients with mild to moderate hypertension and dyslipidemia. This multicenter, randomized, double

  14. Toxicity of 100 nm zinc oxide nanoparticles: a report of 90-day repeated oral administration in Sprague Dawley rats

    Directory of Open Access Journals (Sweden)

    Kim YR

    2014-12-01

    Full Text Available Yu-Ri Kim,1,* Jong-Il Park,2,* Eun Jeong Lee,1 Sung Ha Park,3 Nak-won Seong,2 Jun-Ho Kim,2 Geon-Yong Kim,2 Eun-Ho Meang,2 Jeong-Sup Hong,2 Su-Hyon Kim,2 Sang-Bum Koh,2 Min-Seok Kim,2 Cheol-Su Kim,4 Soo-Ki Kim,4 Sang Wook Son,5 Young Rok Seo,6 Boo Hyon Kang,7 Beom Seok Han,8 Seong Soo A An,9 Hyo-In Yun,9 Meyoung-Kon Kim1 1Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, Korea; 2General Toxicology Team, Korea Testing and Research Institute, Seoul, Korea; 3Department of Biochemistry, University of Bath, Bath, UK; 4Department of Microbiology, Wonju College of Medicine, Yonsei University, Wonju-si, Gangwon, Korea; 5Department of Life Science, Institute of Environmental Medicine for Green Chemistry, Dongguk University, Seoul, Korea; 6Nonclinical Research Institute, Chemon Inc., Yongin, Gyeonggi, Korea; 7Toxicological Research Center, Hoseo University, Ansan, Chungnam, Korea; 8Department of Bionanotechnology, Gachon University, Seongnam, Gyeonggi, Korea; 9College of Veterinary Medicine, Chungnam National University, Daejon, Korea  *These authors contributed equally to this work Abstract: Nanoparticles (NPs are used commercially in health and fitness fields, but information about the toxicity and mechanisms underlying the toxic effects of NPs is still very limited. The aim of this study is to investigate the toxic effect(s of 100 nm negatively (ZnOAE100[-] or positively (ZnOAE100[+] charged zinc oxide (ZnO NPs administered by gavage in Sprague Dawley rats, to establish a no observed adverse effect level, and to identify target organ(s. After verification of the primary particle size, morphology, hydrodynamic size, and zeta potential of each test article, we performed a 90-day study according to Organisation for Economic Co-operation and Development test guideline 408. For the 90-day study, the high dose was set at 500 mg/kg and the middle and low doses were set at 125 mg/kg and 31.25 mg

  15. Is carotid artery evaluation necessary for primary prevention in asymptomatic high-risk patients without atherosclerotic cardiovascular disease?

    Directory of Open Access Journals (Sweden)

    Kim GH

    2015-07-01

    Full Text Available GeeHee Kim,1 Ho-Joong Youn,2 Yun-Seok Choi,2 Hae Ok Jung,2 Wook Sung Chung,2 Chul-Min Kim1 1Department of Internal Medicine, St Vincent’s Hospital, The Catholic University of Korea, Suwon, 2Division of Cardiology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, Republic of Korea Objective: Routine measurement of the carotid intima–media thickness is not recommended in recent clinical practice guidelines for risk assessment of the first atherosclerotic cardiovascular disease (ASCVD event (the definition of which includes acute coronary syndromes, a history of myocardial infarction, stable or unstable angina, coronary or other arterial revascularization, stroke, transient ischemic attack, or peripheral arterial disease presumed to be of atherosclerotic origin. The aim of the present study was to elucidate the role of carotid artery evaluation for primary prevention of ASCVD in asymptomatic high-risk patients visiting a teaching hospital.Methods: Eight hundred seventy-three patients (487 male [55.8%], mean age 59.4±11.5 years who were statin-naive and without ASCVD, which was proven by coronary angiography or coronary CT angiography, were enrolled in this study. The patients underwent carotid scanning in the Medical Department of St Mary’s Hospital from September 2003 to March 2009. ASCVD outcomes were evaluated for median follow-up of 1,402 days.Results: A total of 119 participants experienced ASCVD events. In multivariate Cox regression analysis, age (hazard ratio [HR] =1.026, 95% confidence interval [CI] =1.002–1.050, P=0.033, history of smoking (HR =1.751, 95% CI =1.089–2.815, P=0.021, statin therapy (HR =0.388, 95% CI =0.205–0.734, P=0.004, and carotid plaques (HR =1.556, 95% CI =1.009–2.400, P=0.045 were associated with ASCVD events. In middle-aged group (45≤ age <65, n=473, history of smoking (HR =1.995, 95% CI =1.142–3.485, P=0.015, statin therapy (HR =0.320, 95% CI =0.131

  16. Disease: H01120 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available [KO:K08220] OMIM: 225790 PMID:20206334 (description, gene) Meyer E, Ricketts C, Morgan NV, Morris MR, Pasha ...ugou-Zerelli S, Gonzales M, Meyer V, Wessner M, Feysot CB, Nitschke P, Leticee N, Munnich A, Lyonnet S, Wook

  17. Tri... ekstrima : jugo-vostotshnõi variant

    Index Scriptorium Estoniae

    2005-01-01

    Kagu-Aasia art-house kino - kolme režissööri lühifilmide kassett "Three... Extremes" (2004) : "Dumplings" (Hongkong ; režii Fruit Chan), "Cut" (Lõuna-Korea ; režii Park Chan-Wook), "Box" (Jaapan ; režii Takashi Miike)

  18. Tri... ekstrima : jugo-vostotshnõi variant

    Index Scriptorium Estoniae

    2005-01-01

    Kagu-Aasia art-house kino - kolme režissööri lühifilmide kassett "Three... Extremes" (2004) : "Dumplings" (Hongkong ; režii Fruit Chan), "Cut" (Lõuna-Korea ; režii Park Chan-Wook), "Box" (Jaapan ; režii Takashi Miike)

  19. Prospective Study of Lipoprotein(a) as a Risk Factor for Deteriorating Renal Function in Type 2 Diabetic Patients With Overt Proteinuria

    National Research Council Canada - National Science Library

    Ki-Ho Song; Seung Hyun Ko; Hyung-Wook Kim; Yu-Bae Ahn; Jong-Min Lee; Hyun-Shik Son; Kun-Ho Yoon; Bong-Yun Cha; Kwang-Woo Lee; Ho-Young Son

    2005-01-01

    Prospective Study of Lipoprotein(a) as a Risk Factor for Deteriorating Renal Function in Type 2 Diabetic Patients With Overt Proteinuria Ki-Ho Song , MD , Seung Hyun Ko , MD , Hyung-Wook Kim , MD , Yu-Bae Ahn , MD , Jong-Min Lee , MD...

  20. Self-Aware Computing

    Science.gov (United States)

    2009-06-01

    Paul Johnson, Jae-Wook Lee, Walter Lee, Albert Ma, Arvind Saraf, Mark Seneski, Nathan Shnidman, Volker Strumpen, Matt Frank, Saman Amarasinghe, and...components minimally enabled for operation within a self -aware system  3. APIs for self-aware interactions  1. Develop brand new self-aware operating

  1. Revisiting the dissociation between singing and speaking in expressive aphasia.

    Science.gov (United States)

    Hébert, Sylvie; Racette, Amélie; Gagnon, Lise; Peretz, Isabelle

    2003-08-01

    We investigated the production of sung and spoken utterances in a non-fluent patient, C.C., who had a severe expressive aphasia following a right-hemisphere stroke, but whose language comprehension and memory were relatively preserved. In experiment 1, C.C. repeated familiar song excerpts under four different conditions: spoken lyrics, sung lyrics on original melody, lyrics sung on new but familiar melody and melody sung to a neutral syllable "la". In experiment 2, C.C. repeated novel song excerpts under three different conditions: spoken lyrics, sung lyrics and sung-to-la melody. The mean number of words produced under the spoken and sung conditions did not differ significantly in either experiment. The mean number of notes produced was not different either in the sung-to-la and sung conditions, but was higher than the words produced, hence showing a dissociation between C.C.'s musical and verbal productions. Therefore, our findings do not support the claim that singing helps word production in non-fluent aphasic patients. Rather, they are consistent with the idea that verbal production, be it sung or spoken, result from the operation of same mechanisms.

  2. Systematik zur Gestaltung und Optimierung von wissensintensiven, kooperativen Problemlösungsprozessen in der Produktentwicklung

    OpenAIRE

    Wagner, Kristina

    2008-01-01

    Das Ziel der vorliegenden Arbeit war es, die verteilte Lösung von wissensintensiven Problemen in den frühen Phasen der Produktentwicklung zu unterstützen. Dies umfasst sowohl individuelle als auch kooperative Aspekte der Problemlösung. Im Vordergrund stand dabei die Betrachtung der Aufbau- und Ablauforganisation, die Betrachtung der für die Problemlösung relevanten Wissens- und Lernprozesse und die Etablierung eines ganzheitlichen, integrierten Problemlösungsmanagement. Ferner galt es, realen...

  3. Investigation of Efficient CO Laser Frequency Tripling.

    Science.gov (United States)

    1979-09-01

    C: sueo 149 C sumG 151 1=1 SUNG 152 I"=? SUNG 154 1U22 SUNO 155 luz SUNG 1ss CALI. FRLO SUmG IS? Lz’ SUNO 1SS 10?Sumo 159 ICA? SUNG 160o lull WUHO 161...UPT22 FTN 4.b.’.3JO 1)1/01/78 09.32.25 C CH1IONE 59 CS DL8jiG CI4IONE 60 CS AH~qAYS CHIONE 61 CS GOTOS CHIONE 62 REAL LINEW(59% CINE 6 DIMENSION UfrESO

  4. The archives of solar integral exposures and of spectroheliograms of the former Fraunhofer Institute (now: Kiepenheuer Institute for Solar Physics) in Freiburg and its partial dissolution (German Title: Die Archive solarer Integralaufnahmen und von Spektroheliogrammen des früheren Fraunhofer-Instituts (jetzt: Kiepenheuer-Institut für Sonnenphysik) in Freiburg und ihre teilweise Auflösung)

    Science.gov (United States)

    Wöhl, Hubertus

    The former Fraunhofer-Institut which was founded about 60 years ago and since 1978 is named Kiepenheuer-Institut für Sonnenphysik (KIS), has been for several decades a center to collect information about solar activity. One of the reasons for interest in solar activity were in the beginning attempts to forecast disturbances of (military) radio communication caused by solar eruptions. This would today be called ‘space weather research’. Later daily maps of the sun - showing its activity - were edited for many years. The data needed to describe solar activity were gained mainly from photographic images: Since 1939 white light images of the full solar disk were collected and stored in the archive. Since 1943 in addition spectroheliograms of the full solar disk in H-alpha and in Ca II K3 were collected. These images were taken on glass plates (some on film) of sizes 9 x 12 cm in the case of the white light images and of sizes 6 x 12 cm in the case of the spectroheliograms and were stored in envelopes with additional information written on them. Several hundred of these plates in their envelopes were combined in open wooden boxes each. These boxes were stored in open shelfs in a meeting room of the old solar observatory on the Schauinsland mountain near Freiburg. Within the last years it became obvious that the quality of many plates stored was bad and that the possible scientific usage was becoming very limited. In summer 2002 I started to investigate the quality of the white light images and prepared a data base in MS ACCESS XP about the plates I found which were observed at more than 10 different observing places. The total number of plates checked was 11782. Depending on the quality and possible later usage for an investigation of proper motions in sunspot groups I kept several series of them. Most of the plates kept stem from the years 1945 until 1949 and 1955 until 1959 - when the solar activity was extremely high. In total about 2000 plates were kept. It is intended to digitize as many as possible of these selected plates using a high precision scanner for transparencies. Some examples of digitized images are already available. More details can be found in a text about the history of the Fraunhofer-Institut in the WWW pages of the KIS at: http://www.kis.uni-freiburg.de/kisgeschichte_e.html In summer 2003 I started to investigate the quality of the spectroheliograms on glass plates and to prepare another data base of the material I find in the archive.

  5. 專論/部落格使用者的資訊行為特徵研究/高世樺;林頌堅 | A Study of Features of Blog Users' Information Behaviors / Shih-Hua Kao; Sung-Chien Lin

    Directory of Open Access Journals (Sweden)

    高世樺、林頌堅

    2008-04-01

    Full Text Available

    部落格已經成為諸多新科技中最具有影響力的媒體之一,並對於使用者的資訊尋求行為造成影響。本研究整理部落格的相關概念及功能,並以二十位部落格使 用者的訪談結果對部落格上的資訊尋求行為特徵進行描述。研究結果顯示,使用者在部落格的開始動機、連結方式、辨別標準、監看與提取方式等等都展現了十分豐 富的行為特徵,研究並發現;(1情感聯繫是受訪者經常提及的使用目標,並且這種動機也影響了各種行為特徵;(2使用者會依照自我的需求以及所處的情境 發展出合適的使用方式,這些新使用方式可能不同於發明者與推廣者所設想的最便於使用的功能;(3部落格上的個人經驗是使用者進行資訊尋求的主要原因之 一;(4豐富而精緻的圖像經常能夠吸引使用者進入部落格。

    Blog has already become one of the most influential media among new technologies, and has impacted on users’ information seeking behaviors. This research  utilized an interview survey to explore related concepts and unique functions of blog media. Interviews with 20 blog users were completed and analyzed to depict characteristics of information seeking behaviors founded in the use of blogs. The result shows that the users had performed a variety of behavioral features in motivations of using blogs, ways of linking from one blog to another, criteria of identification among blogs, methods of blog monitoring and extracting and so forth. Some major observations were also found during the interviews conducted: (1 emotion connection is frequently mentioned by users as one of their main purposes of using blogs, which can be found in each characteristic of information seeking behaviors; (2 when users use new functions of blog, based on their respective needs and situations they can develop their own strategies and methods, which can be very different from those provided or assumed by inventors and promoters; (3 personal experience shared by bloggers is one of the primary reasons why users employ blogs to find information needed; (4 abundant and delicate images embedded in blogs can always attract users’ attention.

    頁次:62-77

  6. AA, wide quadrupole on measurement stand

    CERN Multimedia

    CERN PhotoLab

    1981-01-01

    Please look up 8101024 and 8103203 first. Wide quadrupole (QFW, QDW) with end-shims and shimming washers on the measurement stand. With the measurement coil one measured the harmonics of the magnetic field, determined the magnetic centre, and catalogued the effect of washer constellations.

  7. Stemcell Information: SKIP000616 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ng chromosome analysis Yes Genomic PCR Yes ... Yes ... Winston Shim Winston Shim Research and Development Unit, Na...tional Heart Centre Singapore Research and Development Unit, National Heart Centre Singapore Research and Development Unit..., National Heart Centre Singapore ... Research and Development Unit, National Heart Centre Singap

  8. Moulding of Sub-micrometer Surface Structures

    DEFF Research Database (Denmark)

    Pranov, Henrik; Rasmussen, Henrik K.; Larsen, Niels Bent

    2006-01-01

    The experiments strongly suggest that the possibility to injection mould sub-micrometer surface structures in polymers mainly relates to the forces originating from the adhesive energy between polymer and shim.......The experiments strongly suggest that the possibility to injection mould sub-micrometer surface structures in polymers mainly relates to the forces originating from the adhesive energy between polymer and shim....

  9. The Tonal Function of a Task-Irrelevant Chord Modulates Speed of Visual Processing

    Science.gov (United States)

    Escoffier, N.; Tillmann, B.

    2008-01-01

    Harmonic priming studies have provided evidence that musical expectations influence sung phoneme monitoring, with facilitated processing for phonemes sung on tonally related (expected) chords in comparison to less-related (less-expected) chords [Bigand, Tillmann, Poulin, D'Adamo, and Madurell (2001). "The effect of harmonic context on phoneme…

  10. Music training and rate of presentation as mediators of text and song recall.

    Science.gov (United States)

    Kilgour, A R; Jakobson, L S; Cuddy, L L

    2000-07-01

    The present research addresses whether music training acts as a mediator of the recall of spoken and sung lyrics and whether presentation rate is the essential variable, rather than the inclusion of melody. In Experiment 1, 78 undergraduates, half with music training and half without, heard spoken or sung lyrics. Recall for sung lyrics was superior to that for spoken lyrics for both groups. In Experiments 2 and 3, presentation rate was manipulated so that the durations of the spoken and the sung materials were equal. With presentation rate equated, there was no advantage for sung over spoken lyrics. In all the experiments, those participants with music training outperformed those without training in all the conditions. The results suggest that music training leads to enhanced memory for verbal material. Previous findings of melody's aiding text recall may be attributed to presentation rate.

  11. FTA a Long Way Away

    Institute of Scientific and Technical Information of China (English)

    LlU XlNLIAN

    2011-01-01

    "Boasting the wvorld's second and third biggest economies,China and Japan,northeast Asia has been the most dynamic region in the world in recent decades,”said Chae Wook,Director of the South Korea Institute for International Economic Policy,at the Seventh China Jilin-Northeast Asia Investment and Trade Expo held on September 6-11 in Changchun,capital of northeast China's Jilin Province.

  12. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    Science.gov (United States)

    2013-05-01

    Cho, Nattapol Damrongplasit, Dr. Nuo Xu, Dr. Byron Ho, Dr. Zach Jacobson, Wook Hyun Kwon, Dr. Li-Wen Hung, Dr. Darsen Lu, Dr. Cheuk Chi Lo...N. Sharpe Jr, and O. Jadaan, “Fracture strength of polysilicon at stress concentrations,” Journal of Microelectromechanical Systems, vol. 12, no. 3...the consumer market from personal computers (PCs) to mobile devices sparked a new era in computation that makes energy efficient computing devices all

  13. Batteries: encapsulated monoclinic sulfur for stable cycling of li-s rechargeable batteries (adv. Mater. 45/2013).

    Science.gov (United States)

    Moon, San; Jung, Young Hwa; Jung, Wook Ki; Jung, Dae Soo; Choi, Jang Wook; Kim, Do Kyung

    2013-12-03

    On page 6547 Do Kyung Kim, Jang Wook Choi and co-workers describe a highly aligned and carbon-encapsulated sulfur cathode synthesized with an AAO template that exhibits a high and long cycle life, and the best rate capability based on the complete encapsulation of sulfur (physical) and implementation of the monoclinic sulfur phase (chemical). © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Several Factors of Library Publishing Services Facilitate Scholarly Communication Functions. A Review of: Park, J.-H., & Shim, J. (2011. Exploring how library publishing services facilitate scholarly communication. Journal of Scholarly Publishing, 43(1, 76-89. doi: 10.1353/scp.2011.0038

    Directory of Open Access Journals (Sweden)

    Leslie Bussert

    2012-12-01

    Full Text Available Objective – To identify and examine thefactors of library publishing services thatfacilitate scholarly communication.Design – Analysis of library publishing serviceprograms.Setting – North American research libraries.Subjects – Eight research libraries selectedfrom the signatories for the Compact for Open-Access Publishing Equity (COPE CornellUniversity Library’s Center for InnovativePublishing; Dartmouth College Library’sDigital Publishing Program and ScholarsPortal Project; MIT Libraries’ Office ofScholarly Publishing and Licensing; ColumbiaUniversity Libraries’ Center for DigitalResearch and Scholarship; University ofMichigan Library’s Scholarly PublishingOffice; Duke University Library’s Office ofScholarly Communications; University ofCalgary Libraries and Cultural Resources’Centre for Scholarly Communication; andSimon Fraser University Library’s ScholarlyPublishing.Methods – The authors used Roosendaal andGeurt’s (1997 four functions of scholarlycommunication to analyze and categorizelibrary publishing services provided bylibraries included in the study. The fourfunctions of scholarly communication includeregistration, certification, awareness, andarchiving.Main Results – Analysis of the registration functions provided by library publishing services in this study revealed three types of facilitating factors: intellectual property, licensing, and publishing. These include services such as repositories for digital scholarly work and research, ISBN/ISSN registration, and digital publishing. Analysis of archiving functions demonstrated that most programs in the study focus on repository-related services in support of digital content preservation of papers, datasets, technical reports, etc. Analysis of certification functions provided by these services exposed a focus on expert review and research support. These include services like professional assessment of information sources, consultation on appropriate literature and information-seeking tools, and writing or copyright advisory services. Analysis of awareness function showed search aids and knowledge-sharing platforms to be the main facilitating factors. These include services like metadata application, schema, and standards or scholarly portals enabling knowledge-sharing among scholars.Conclusion – This study identified several services offered by these library publishing programs which can be categorized as facilitators under Roosendaal and Geurt’s (1997 four functions of scholarly communication. The majority of the libraries in the study treated library publishing services as part of broader scholarly communication units or initiatives. Digital publishing (registration function was offered by all programs analyzed in the study, while traditional peer-review services (certification function were not. Widely adopted among programs in the study were the use of social networking tools (awareness function and self-publishing (archiving function. The authors recommend developing services that facilitate peer review and assert the need to provide a knowledge-sharing mechanism within the academic community that facilitates the scholarly communication process.

  15. From static to dynamic 1.5T MRI-linac prototype: impact of gantry position related magnetic field variation on image fidelity.

    Science.gov (United States)

    Crijns, Sjoerd; Raaymakers, Bas

    2014-07-07

    Recently, the MRI-linac prototype at UMC Utrecht was upgraded with a ring-based gantry, where all linac components are mounted on a ring around the MR scanner. Although adaptations have been made to both linac and MR magnets in order to account for mutual magnetic interference, interference problems cannot be ruled out completely. Therefore, in this paper the impact of gantry position dependent magnetic field inhomogeneity variation on the geometrical accuracy of acquired MR images is quantified. Magnetic field maps were acquired in a large field of view for static gantry positions in shimmed and un-shimmed conditions. Reproducibility of the shim settings was assessed. From the fieldmaps, a minimum gradient strength needed to acquire images with geometric distortions of, at most, 1 mm was derived. Moreover, imaging during gantry rotation was performed for a range of imaging parameters and rotation speeds. From the measurements we conclude that images with good geometric fidelity can be obtained for all static gantry positions, provided that shimming is performed for each new gantry position. This indicates that the present prototype is suitable for static IMRT scenarios. Shim settings are highly reproducible, suggesting that shimming via look-up tables is feasible. Finally, imaging during gantry rotation may produce severely distorted images at present and is likely to require advanced compensation methods such as dynamic shimming or higher order reconstruction.

  16. Sub-Transport Layer Coding

    DEFF Research Database (Denmark)

    Hansen, Jonas; Krigslund, Jeppe; Roetter, Daniel Enrique Lucani

    2014-01-01

    Packet losses in wireless networks dramatically curbs the performance of TCP. This paper introduces a simple coding shim that aids IP-layer traffic in lossy environments while being transparent to transport layer protocols. The proposed coding approach enables erasure correction while being...... oblivious to the congestion control algorithms of the utilised transport layer protocol. Although our coding shim is indifferent towards the transport layer protocol, we focus on the performance of TCP when ran on top of our proposed coding mechanism due to its widespread use. The coding shim provides gains...

  17. The Armed Forces Health Surveillance Center: Global Emerging Infections Surveillance & Response System, FY 2010

    Science.gov (United States)

    2010-01-01

    MR Duffy, MJ Shim, S Guerra , F Guerra , G Mills, J Verani, B Alsip, S Lindstrom, B Shu, S Emery, AL Cohen, M Menon, AM Fry, F Dawood, VP Fonseca...eid1604.091658. 57. Morgan OW, S Parks, T Shim, PA Blevins, PM Lucas, R Sanchez, N Walea, F Loustalot, MR Duffy, MJ Shim, S Guerra , F Guerra , G Mills, J...captured at a U.S. military training site (Dagmar North), Republic of Korea, 2001-2004,” Mil Med, 174 (10), 1061-7. 69. Paz -Soldan VA, ST Stoddard, G

  18. 国际交流(英文)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Gu Xiulian Meets C.B.Sung,Wife顾秀莲会见沈坚白夫妇On December 20,2006,Gu Xiulian (middle),Vice-Chairperson of the Standing Committee of the National People's Congress and President of the All-China Women's Federation (ACWF),met C.B.Sung (second from left),Chairman of the Board of The 1990 Institute,based in the United States,and his wife,Beulah K.Sung (second from right),at the ACWF.

  19. ORIGINAL ARTICLE Multimodal magnetic resonance imaging ...

    African Journals Online (AJOL)

    has been shown to lengthen the progression-free period without significantly affecting .... PWI (T2*-weighted, gradient-echo single-shot EPI sequence) was performed during a ... multiple-angle projection (MAP) shimming. Spectral maps were.

  20. Aluminum for bonding Si-Ge alloys to graphite

    Science.gov (United States)

    Eggemann, Robert V.

    1976-01-13

    Improved thermoelectric device and process, comprising the high-temperature, vacuum bonding of a graphite contact and silicon-germanium thermoelectric element by the use of a low void, aluminum, metallurgical shim with low electrical resistance sandwiched therebetween.

  1. Eine lohnende Investition mit ungewissem Ausgang

    OpenAIRE

    Seelos, Christian; Mair, Johanna

    2016-01-01

    Innovation in sozialen Organisationen bedeutet vor allem eines nicht: die Garantie auf eine schnelle Lösung von Problemen. Vielmehr ist Innovation ein Prozess, der das Lernpotenzial des Unternehmens steigert und damit auch den gewollten Mehrwert generiert.

  2. Music training and rate of presentation as mediators of text and song recall

    National Research Council Canada - National Science Library

    Kilgour, Andrea R; Jakobson, Lorna S; Cuddy, Lola L

    2000-01-01

    The present research addresses whether music training acts as a mediator of the recall of spoken and sung lyrics and whether presentation rate is the essential variable, rather than the inclusion of melody...

  3. AA, wide quadrupole on measurement stand

    CERN Multimedia

    CERN PhotoLab

    1981-01-01

    Please look up 8101024 first. Shims and washers on the wide quadrupoles (QFW, QDW; located in the lattice where dispersion was large) served mostly for corrections of those lattice parameters which were a function of momentum. After mounting shims and washers, the quadrupoles were measured to determine their magnetic centre and to catalogue the effect of washer constellations. Raymond Brown is busy measuring a wide quad.

  4. Advanced Bristle Seals for Gas Turbine Engines

    Science.gov (United States)

    1993-01-28

    test sequence I retained the .003 inch shim and added a positive seal between the shim stock and the housing using Room Temperature Vulcanizing (RTV...113.4 200 6 1.131 1.040 175.142 0.219 * STANDARD CUBIC FOOT PER MINUTE u FLOW(cfm) OF AIR 2 70F/14.7psil TABLE C-8. TESI SEQUENCE H DATA "H. STATIC

  5. Time-and Space-Resolved Spectroscopic Investigation on pi-Conjugated Nanostructures

    Science.gov (United States)

    2014-07-30

    Bonding Interactions of meso-Imidazolyl Groups Hirotaka Mori, Young Mo Sung, Byung Sun Lee, Dongho Kim and Atsuhiro Osuka Angew . Chem. Int. Ed...Chi, Jun Ding, Juan Casado, Dongho Kim and Jishan Wu Angew . Chem. Int. Ed., 52(33), 8561-8565. August 12, 2013 13. S2 Fluorescence Dynamics of...meso-Aryl-substituted Subporphyrins Jooyoung Sung, Pyosang Kim, Shun Saga, Shin-ya Hayashi, Atsuhiro Osuka, and Dongho Kim Angew . Chem. Int. Ed., 52

  6. Robust Speech Processing & Recognition: Speaker ID, Language ID, Speech Recognition/Keyword Spotting, Diarization/Co-Channel/Environmental Characterization, Speaker State Assessment

    Science.gov (United States)

    2015-10-01

    integrated spectral and prosody based LID solutions. For co-channel and diarization, new algorithms based on gammatone subband frequency modulation was...17 9 Vowel classification accuracy or spoken & sung vowels using k-NN classifier ..….……. 19 10 Vowel classification accuracy for spoken & sung...27 18 TO-Combo-SAD decisions and scream detection using CompSeg ………………………. 29 19 Distribution of spectral center of gravity (SCG) in

  7. Species of Cordyceps-like Fungi from Guangxi, China%广西的虫草种类

    Institute of Scientific and Technical Information of China (English)

    宋斌; 吴兴亮; 李泰辉

    2011-01-01

    本文报道了广西虫草类真菌2科3属23种,其中珊瑚虫草Cordyceps martialis Speg.、红座虫草Cordyceps roseostromataKobayasi & Shimizu和蚁窝线虫草Ophiocordyceps formicarum(Kobayasi)G.H.Sung,J.M.Sung,Hywel-Jones & Spatafora是广西新记录种.

  8. Happy Handwashing Song

    Centers for Disease Control (CDC) Podcasts

    2010-02-25

    This song (sung to the tune of Happy Birthday) encourages kids to wash their hands with soap and water to keep germs away. The song is sung twice through, the recommended length of time to wash hands. Sing along!  Created: 2/25/2010 by National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID), Division of Global Migration and Quarantine (DGMQ).   Date Released: 2/25/2010.

  9. Formation of Acetic Acid by Aqueous-Phase Oxidation of Ethanol with Air in the Presence of a Heterogeneous Gold Catalyst

    DEFF Research Database (Denmark)

    Christensen, Claus H.; Jørgensen, B.; Hansen, Jeppe Rass

    2006-01-01

    Die selektive Oxidation von Ethanol zu Essigsäure gelingt in wässriger Lösung mit dem Oxidans Luft an einem Gold-Heterogenkatalysator (siehe Bild). Bei 423 K und einem O2-Druck von 0.6 MPa verläuft diese Reaktion glatt in saurer wässriger Lösung in Ausbeuten um 90 %. CO2 ist das einzige Nebenprod...

  10. Mongghul Duraasi Dau

    OpenAIRE

    Ha, Mingzong

    2009-01-01

    Two Mongghul drinking songs were recorded. The first song is sung in Tibetan, while the second is in local Chinese. Most Mongghul songs are in Mongghul, however, a few are in the local Tibetan and Chinese languages. Song one: This Mongghul song sung in Tibetan shows close historical contact between the Mongghul and Tibetan. Today, as Chinese pop music permeates the daily lives of Mongghul people and as the mass media diverts attention from folksongs, young Monggh...

  11. Happy Handwashing Song

    Centers for Disease Control (CDC) Podcasts

    2010-02-25

    This song (sung to the tune of Happy Birthday) encourages kids to wash their hands with soap and water to keep germs away. The song is sung twice through, the recommended length of time to wash hands. Sing along!  Created: 2/25/2010 by National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID), Division of Global Migration and Quarantine (DGMQ).   Date Released: 2/25/2010.

  12. The correlation between highly sensitive C-reactive protein levels and erectile function among men with late-onset hypogonadism.

    Science.gov (United States)

    Shigehara, Kazuyoshi; Konaka, Hiroyuki; Ijima, Masashi; Nohara, Takahiro; Narimoto, Kazutaka; Izumi, Koji; Kadono, Yoshifumi; Kitagawa, Yasuhide; Mizokami, Atsushi; Namiki, Mikio

    2016-12-01

    We investigated the correlation between highly sensitive C-reactive protein (hs-CRP) levels and erectile function, and assessed the clinical role of hs-CRP levels in men with late-onset hypogonadism (LOH) syndrome. For 77 participants, we assessed Sexual Health Inventory for men (SHIM) score, Aging Male Symptoms (AMS) score and International Prostate Symptom Score (IPSS). We also evaluated free testosterone (FT), hs-CRP, total cholesterol, triglyceride levels, high density lipoprotein cholesterol, hemoglobin A1c, body mass index, waist size and blood pressure. We attempted to identify parameters correlated with SHIM score and to determine the factors affecting cardiovascular risk based on hs-CRP levels. A Spearman rank correlation test revealed that age, AMS score, IPSS and hs-CRP levels were significantly correlated with SHIM score. Age-adjusted analysis revealed that hs-CRP and IPSS were the independent factors affecting SHIM score (r= -0.304 and -0.322, respectively). Seventeen patients belonged to the moderate to high risk group for cardiovascular disease, whereas the remaining 60 belonged to the low risk group. Age, FT value and SHIM score showed significant differences between the two groups. A multivariate regression analysis demonstrated that SHIM score was an independent factor affecting cardiovascular risk (OR: 0.796; 95%CI: 0.637-0.995).

  13. FTA a Long Way Away

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Northeast Asia’s major stakeholders forge closer ties without a formal mechanism "Boasting the world’s second and third biggest economies,China and Japan,northeast Asia has been the most dynamic region in the world in recent decades," said Chae Wook,Director of the South Korea Institute for International Economic Policy,at the Seventh China Jilin-Northeast Asia Investment and Trade Expo held on September 6-11 in Changchun,capital of northeast China’s Jilin Province.

  14. Does music training facilitate the mnemonic effect of song? An exploration of musicians and nonmusicians with and without Alzheimer's dementia.

    Science.gov (United States)

    Baird, Amee; Samson, Séverine; Miller, Laurie; Chalmers, Kerry

    2017-02-01

    The efficacy of using sung words as a mnemonic device for verbal memory has been documented in persons with probable Alzheimer's dementia (AD), but it is not yet known whether this effect is related to music training. Given that music training can enhance cognitive functioning, we explored the effects of music training and modality (sung vs. spoken) on verbal memory in persons with and without AD. We used a mixed factorial design to compare learning (5 trials), delayed recall (30-min and, 24-hour), and recognition of sung versus spoken information in 22 healthy elderly (15 musicians), and 11 people with AD (5 musicians). Musicians with AD showed better total learning (over 5 trials) of sung information than nonmusicians with AD. There were no significant differences in delayed recall and recognition accuracy (of either modality) between musicians with and without AD, suggesting that music training may facilitate memory function in AD. Analysis of individual performances showed that two of the five musicians with AD were able to recall some information on delayed recall, whereas the nonmusicians with AD recalled no information on delay. The only significant finding in regard to modality (sung vs. spoken) was that total learning was significantly worse for sung than spoken information for nonmusicians with AD. This may be due to the need to recode information presented in song into spoken recall, which may be more cognitively demanding for this group. This is the first study to demonstrate that music training modulates memory of sung and spoken information in AD. The mechanism underlying these results is unclear, but may be due to music training, higher cognitive abilities, or both. Our findings highlight the need for further research into the potentially protective effect of music training on cognitive abilities in our aging population.

  15. EDITORIAL: Focus on Heart and Mind

    Science.gov (United States)

    Bodenschatz, Eberhard; Wolf, Fred

    2008-01-01

    tractable to support a comprehensive analysis of functional performance at the systems level. Analogously, experimental work increasingly probes the system dynamics simultaneously at multiple levels from cell to whole organ. Here an invaluable contribution of physics to the experimental characterization of large scale activity in cardiac and neuronal tissues is the currently emerging high level of quantitative precision and control. Long-term high precision recording of large scale activity patterns of neural and cardiac tissues increasingly supports the formulation of quantitative phenomenological theories of complex dynamical states as well the realization of algorithms for manipulating and controlling them. Both quantitative phenomenology and control are not only essential for bridging theory and experiment in complex systems; they are also indispensable for turning scientific insight into diagnostic progress and improved treatment for the affected heart and mind. The present Focus Issue in New Journal of Physics reflects well the richness and excitement of this currently rapidly evolving field. It combines theoretical and experimental approaches and covers analyses ranging from the organ level over investigations of model systems to the biophysics of individual cells. The articles below represent the first contributions to this collection and further additions will appear in the near future. Focus on Heart and Mind Contents 'Heart' contributions Spiral wave drift and complex-oscillatory spiral waves caused by heterogeneities in two-dimensional in vitro cardiac tissues Sung-Jae Woo, Jin Hee Hong, Tae Yun Kim, Byung Wook Bae and Kyoung J Lee Epicardial wavefronts arise from widely distributed transient sources during ventricular fibrillation in the isolated swine heart J M Rogers, G P Walcott, J D Gladden, S B Melnick, R E Ideker and M W Kay Efficient control of spiral wave location in an excitable medium with localized heterogeneities J Schlesner, V S Zykov, H Brandtst

  16. Quantitative prediction of radio frequency induced local heating derived from measured magnetic field maps in magnetic resonance imaging: A phantom validation at 7 T

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xiaotong; Liu, Jiaen [Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455 (United States); Van de Moortele, Pierre-Francois; Schmitter, Sebastian [Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota 55455 (United States); He, Bin, E-mail: binhe@umn.edu [Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455 (United States); Institute for Engineering in Medicine, University of Minnesota, Minneapolis, Minnesota 55455 (United States)

    2014-12-15

    Electrical Properties Tomography (EPT) technique utilizes measurable radio frequency (RF) coil induced magnetic fields (B1 fields) in a Magnetic Resonance Imaging (MRI) system to quantitatively reconstruct the local electrical properties (EP) of biological tissues. Information derived from the same data set, e.g., complex numbers of B1 distribution towards electric field calculation, can be used to estimate, on a subject-specific basis, local Specific Absorption Rate (SAR). SAR plays a significant role in RF pulse design for high-field MRI applications, where maximum local tissue heating remains one of the most constraining limits. The purpose of the present work is to investigate the feasibility of such B1-based local SAR estimation, expanding on previously proposed EPT approaches. To this end, B1 calibration was obtained in a gelatin phantom at 7 T with a multi-channel transmit coil, under a particular multi-channel B1-shim setting (B1-shim I). Using this unique set of B1 calibration, local SAR distribution was subsequently predicted for B1-shim I, as well as for another B1-shim setting (B1-shim II), considering a specific set of parameter for a heating MRI protocol consisting of RF pulses plaid at 1% duty cycle. Local SAR results, which could not be directly measured with MRI, were subsequently converted into temperature change which in turn were validated against temperature changes measured by MRI Thermometry based on the proton chemical shift.

  17. Development of a compact magnetic resonance imaging system for a cold room

    Science.gov (United States)

    Adachi, Satoru; Ozeki, Toshihiro; Shigeki, Ryosuke; Handa, Shinya; Kose, Katsumi; Haishi, Tomoyuki; Aoki, Masaaki

    2009-05-01

    A compact magnetic resonance imaging (MRI) system for a cold (-5 °C) room has been developed to acquire MR images below the freezing point of water. The MRI system consists of a 1.0 T permanent magnet, a higher-order shim coil set, and a gradient coil probe, installed in the cold room, and a compact MRI console installed in a room at normal temperature (20-25 °C). The most difficult problem for the installation of the MRI system in the cold room was the degradation of the field homogeneity of the permanent magnet shimmed at 25 °C. To overcome this problem, higher-order shim coils were developed and the temperature variation of the magnetic field distribution was measured using a standard phantom with and without shim coil currents. As a result, it was confirmed that the homogeneity (the difference between the minimum and maximum values) of the magnetic field in the 17×17×19 mm3 rectangular parallelepiped region was improved from 117 to 59 ppm using an appropriate combination of shim coil currents. A snowpack immersed in dodecane (C12H26) was imaged using a driven-equilibrium three-dimensional (3D) spin-echo sequence at -5 °C. The visualized 3D structure of the snowpack demonstrated the effectiveness of our approach.

  18. For 5-Month-Old Infants, Melodies Are Social.

    Science.gov (United States)

    Mehr, Samuel A; Song, Lee Ann; Spelke, Elizabeth S

    2016-04-01

    For 1 to 2 weeks, 5-month-old infants listened at home to one of two novel songs with identical lyrics and rhythms, but different melodies; the song was sung by a parent, emanated from a toy, or was sung live by a friendly but unfamiliar adult first in person and subsequently via interactive video. We then tested the infants' selective attention to two novel individuals after one sang the familiar song and the other sang the unfamiliar song. Infants who had experienced a parent singing looked longer at the new person who had sung the familiar melody than at the new person who had sung the unfamiliar melody, and the amount of song exposure at home predicted the size of that preference. Neither effect was observed, however, among infants who had heard the song emanating from a toy or being sung by a socially unrelated person, despite these infants' remarkable memory for the familiar melody, tested an average of more than 8 months later. These findings suggest that melodies produced live and experienced at home by known social partners carry social meaning for infants. © The Author(s) 2016.

  19. Development of a temperature-variable magnetic resonance imaging system using a 1.0T yokeless permanent magnet.

    Science.gov (United States)

    Terada, Y; Tamada, D; Kose, K

    2011-10-01

    A temperature variable magnetic resonance imaging (MRI) system has been developed using a 1.0 T permanent magnet. A permanent magnet, gradient coils, radiofrequency coil, and shim coil were installed in a temperature variable thermostatic bath. First, the variation in the magnetic field inhomogeneity with temperature was measured. The inhomogeneity has a specific spatial symmetry, which scales linearly with temperature, and a single-channel shim coil was designed to compensate for the inhomogeneity. The inhomogeneity was drastically reduced by shimming over a wide range of temperature from -5°C to 45°C. MR images of an okra pod acquired at different temperatures demonstrated the high potential of the system for visualizing thermally sensitive properties.

  20. Melanite garnet-bearing nepheline syenite minor intrusion in Mawpyut ultramafic–mafic complex, Jaintia Hills, Meghalaya

    Indian Academy of Sciences (India)

    Monoj Maitra; J S David; S Bhaduri

    2011-12-01

    Mawpyut igneous suite in Jaintia Hills of Meghalaya plateau comprises differentiated suite of ultramafic–mafic rocks. The complex differs from other ultramafic–alkaline–carbonatite igneous emplacements of Shillong plateau and Mikir Hills like Jesra, Sung, Samchampi complexes, by the absence of alkaline–carbonatite rocks as major litho-units. Melanite garnet-bearing nepheline syenite, occurs as late phase minor intrusion in Mawpyut igneous complex, posseses alkaline character and shows inubiquitous relation with the host ultramafic–mafic rocks. On the other hand, this alkaline intrusive bodies of the Mawpyut igneous complex shows chemico-mineralogical resemblance with garnet-bearing nepheline syenite, ijolite litho-members of Jesra, Sung, Samchampi complexes of the region. It is interpreted that melanite garnet-bearing nepheline syenite intrusion in Mawpyut is contemporaneous with Jesra, Sung, Samchampi ultramafic–alkaline–carbonatite complexes and the host rocks of Mawpyut complex is an earlier magmatic activity possibly from a comparatively least enriched source.

  1. Undulator Beam Pipe Magnetic Shielding Effect Tests

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Andrew; Wolf, Zachary; /SLAC

    2010-11-23

    The proposed stainless steel beampipe for the LCLS undulator has a measurable shielding effect on the magnetic field of the LCLS undulators. This note describes the tests used to determine the magnitude of the shielding effect, as well as deviations in the shielding effect caused by placing different phase shims in the undulator gap. The effect of the proposed Steel strongback which will be used to support the beam pipe, was also studied. A hall probe on a 3 axis movement system was set up to measure the main component of the magnetic field in the Prototype Undulator. To account for temperature variations of the magnetic field of the undulator for successive tests, a correction is applied which is described in this technical note. Using this method, we found the shielding effect, the amount which the field inside the gap was reduced due to the placement of the beampipe, to be {approx}10 Gauss. A series of tests was also performed to determine the effect of phase shims and X and Y correction shims on the shielding. The largest effect on shielding was found for the .3 mm phase shims. The effect of the .3 mm phase shims was to increase the shielding effect {approx}4 Gauss. The tolerance for the shielding effect of the phase shims is less than 1 gauss. The effect of the strongback was seen in its permanent magnetic field. It introduced a dipole field across the measured section of the undulator of {approx}3 gauss. This note documents the tests performed to determine these effects, as well as the results of those tests.

  2. Tuning and characterization of the {open_quotes}Teufel{close_quotes}-undulator

    Energy Technology Data Exchange (ETDEWEB)

    Verschuur, J.W.J.; Ernst, G.J.; Witteman, W.J. [Univ. of Twente, Enschede (Netherlands)

    1995-12-31

    Three important criteria are used to tune the undulator are: reduce longitudinal phase errors, have approximately equal two plane focusing and have a good overlap between the electron beam and the optical beam. Although these criteria are the main design goals it is hard to meet them directly from the assembling. Small errors inevitably appear during the assembly, even when care is taken to keep the tolerances as tight as possible. The magnetic field was constantly monitored during construction using the pulsed wire method. However some kind of tuning mechanism is always needed to improve the performance of the undulator. The undulator we designed and build is of the Hybrid type, i.e. permanent magnets and high permeable poles. The well known method of using small permanent magnets to correct the field errors is nearly impossible due to the presence of iron poles. Hence, as a logical step, we decided to try to correct the various errors with shims in the form of small iron plates. The shims were put on the pole face at the edge of the poles. Different configurations were used to correct the different kind of errors. In the presentation an overview of the various shim configurations will be discussed. Steering errors are quite easy to correct, since only dipole fields are involved. We did put quite some effort in correcting the quadrupole errors. Gradients dBy/dx and dBx/dy were easy to correct with two shims on one side. The other gradients, on the other hand needed extensive shimming to be corrected. The error correction is limited by the presence of sextupole errors. We even found by experience that sextupole errors increased with the number of shims used. The ratio of the focusing strength of the undulator is measured to be 3/2, being slightly stronger in the direction of the wiggle motion. Longitudinal phase errors are introduced by amplitude and wavelength deviations in the undulator.

  3. Pulse-modulated second harmonic imaging microscope quantitatively demonstrates marked increase of collagen in tumor after chemotherapy

    Science.gov (United States)

    Raja, Anju M.; Xu, Shuoyu; Sun, Wanxin; Zhou, Jianbiao; Tai, Dean C. S.; Chen, Chien-Shing; Rajapakse, Jagath C.; So, Peter T. C.; Yu, Hanry

    2010-09-01

    Pulse-modulated second harmonic imaging microscopes (PM-SHIMs) exhibit improved signal-to-noise ratio (SNR) over conventional SHIMs on sensitive imaging and quantification of weak collagen signals inside tissues. We quantify the spatial distribution of sparse collagen inside a xenograft model of human acute myeloid leukemia (AML) tumor specimens treated with a new drug against receptor tyrosine kinase (ABT-869), and observe a significant increase in collagen area percentage, collagen fiber length, fiber width, and fiber number after chemotherapy. This finding reveals new insights into tumor responses to chemotherapy and suggests caution in developing new drugs and therapeutic regimens against cancers.

  4. [Design of high performance DSP-based gradient calculation module for MRI].

    Science.gov (United States)

    Pan, Wenyu; Zhang, Fu; Luo, Hai; Zhou, Heqin

    2011-05-01

    A gradient calculation module based on high performance DSP was designed to meet the needs of digital MRI spectrometer. According to the requirements of users, this apparatus can achieve rotation transformation, pre-emphasis, shimming and other gradient calculation functions in a single chip of DSP. It then outputs gradient waveform data of channel X, Y, Z and shimming data of channel B0. Experiments show that the design has good versatility and can satisfy the functional, speed and accuracy requirements of MRI gradient calculation. It provides a practical gradient calculation solution for the development of digital spectrometer.

  5. Real-time simulation of energy management in a domestic consumer

    DEFF Research Database (Denmark)

    Fernandes, F.; Silva, M.; Faria, P.

    2013-01-01

    . The present work focuses on a real scenario of the LASIE laboratory, located at the Polytechnic of Porto. Laboratory systems are managed by the SCADA House Intelligent Management (SHIM), already developed by the authors based on a SCADA system. The SHIM capacities have been recently improved by including real......-time simulation from Opal RT. This makes possible the integration of Matlab®/Simulink® real-time simulation models. The main goal of the present paper is to compare the advantages of the resulting improved system, while managing the energy consumption of a domestic consumer....

  6. Solar Cell Panel and the Method for Manufacturing the Same

    Science.gov (United States)

    Richards, Benjamin C. (Inventor); Sarver, Charles F. (Inventor); Naidenkova, Maria (Inventor)

    2016-01-01

    According to an aspect of an embodiment of the present disclosure, there is provided a solar cell panel and a method for manufacturing the same. The solar cell panel comprises: a solar cell for generating electric power from sunlight; a coverglass for covering the solar cell; transparent shims, which are disposed between the solar cell and the coverglass at the points where the distance between the solar cell and the coverglass needs to be controlled, and form a space between the solar cell and the coverglass; and adhesive layer, which fills the space between the solar cell and the coverglass and has the thickness the same as that of the transparent shims.

  7. Auswirkungen des Urin-pH auf das Ballonvolumen bei Dauerkathetern

    OpenAIRE

    Pannek J; Weiß D

    2007-01-01

    Einleitung: Eine häufige Komplikation der transurethralen oder suprapubischen Dauerkatheterversorgung ist die Dislokation durch eine insuffiziente Katheterblockung. Die Auswirkungen des Urin-pH auf das Ballonvolumen sind dabei bisher nicht untersucht. Methodik: In einer In-vitro-Studie wurden Dauerkatheter aus Silikon und Latex mit entweder 10%iger Glyzerinlösung oder mit 0,9%iger NaCl-Lösung geblockt und 14 Tage bei verschiedenen pH-Werten in künstlichem Urin gelagert. Nach diesem Zeitraum ...

  8. Electronic Learning Systems in Hong Kong Business Organizations: A Study of Early and Late Adopters

    Science.gov (United States)

    Chan, Simon C. H.; Ngai, Eric W. T.

    2012-01-01

    Based on the diffusion of innovation theory (E. M. Rogers, 1983, 1995), the authors examined the antecedents of the adoption of electronic learning (e-learning) systems by using a time-based assessment model (R. C. Beatty, J. P. Shim, & M. C. Jones, 2001), which classified adopters into categories upon point in time when adopting e-learning…

  9. DREAM - A Novel Approach for Robust, Ultra-Fast, Multi-Slice B1 Mapping

    NARCIS (Netherlands)

    Nehrke, K.; Boernert, P.

    2012-01-01

    Fast and robust in vivo B1 mapping is an essential prerequisite forquantitative MRI or multi-element transmit applications like RF-shimming or accelerated multi-dimensional RF pulses. However, especially at higher field strength, the acquisition speed of current B1-mapping approaches is typicall

  10. Tumor-Selective Targeting of Androgen Receptor Expression by Novel Small-Molecule Agents

    Science.gov (United States)

    2013-05-01

    Cinalli, R. M., Alavi, A., Rudin , C. M., and Thompson, C. B. (2004) Cancer Res. 64, 3892–3899 5. Osthus, R. C., Shim, H., Kim, S., Li, Q., Reddy, R...Cancer 2008;8(9):705–713. 4. Elstrom RL, Bauer DE, Buzzai M, Karnauskas R, Harris MH, Plas DR, Zhuang H, Cinalli RM, Alavi A, Rudin CM, Thomp- son CB

  11. JPRS Report Near East South Asia.

    Science.gov (United States)

    2007-11-02

    conducting party meetings. After Dar’ai, the SHAS secretariat chose MK Shim’on Ben Shlomo as secretary general. The scholars council did not...Mr Arun Nehru, Mr V C Shukla and come together to mobilise the people Mr Arif Mohammed Khan. against terrorism. Briefing newsmen later, AICC gen

  12. CESAR, 2 MeV electron storage ring; construction period; quadrupole.

    CERN Multimedia

    Service Photo; CERN PhotoLab

    1962-01-01

    One of the 24 quadrupoles. They were made of massive (non-laminated) soft iron, which at the low field-strength (35 G on the pole-tips) presented problems. Later they were fitted with shims on all 4 poles, to correct the quadrupole and sextupole components.

  13. FPGA Accelerated Discrete-SURF for Real-Time Homography Estimation

    Science.gov (United States)

    2015-03-26

    things amazon needs to get its delivery drones off the ground.” 21. E. Rosten and T. Drummond, “Fusing points and lines for high performance tracking...Morrison, and D. H. Shim, “Persis- tent UAV service: An improved scheduling formulation and prototypes of system components,” Journal of Intelligent

  14. On the Injection Molding of Nanostructured Polymer Surfaces

    DEFF Research Database (Denmark)

    Pranov, Henrik; Rasmussen, Henrik K.; Larsen, Niels Bent;

    2006-01-01

    Well-defined nano-topographies were prepared by electron-beam lithography and electroplated to form nickelshims. The surface pattern consisted of square pillars repeated equidistantly within the plane of the surface in a perpendicular arrangement. The width and distance between the squares both...... mold sub-micrometer surface structures in polymers mainly relates to adhesive energy between polymer and shim....

  15. Joining of beryllium by braze welding technique: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Banaim, P.; Abramov, E. [Ben-Gurion Univ. of the Negev, Beersheba (Israel); Zalkind, S.; Eden, S.

    1998-01-01

    Within the framework of some applications, there is a need to join beryllium parts to each other. Gas Tungsten Arc Braze Welds were made in beryllium using 0.3 mm commercially Aluminum (1100) shim preplaced at the joint. The welds exhibited a tendency to form microcracks in the Fusion Zone and Heat Affected Zone. All the microcracks were backfilled with Aluminum. (author)

  16. 24 CFR 3285.5 - Definitions.

    Science.gov (United States)

    2010-04-01

    .... Pilings, columns, footings, piers, foundation walls, shims, and any combination thereof that, when... wood; manufactured concrete stands; concrete blocks; and portions of foundation walls. Ramada. Any... determined by dividing the ultimate load of a component or system by an appropriate factor of safety. ...

  17. Completion of Main Magnet Fabrication for CYCIAE-100

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The main magnet of CYCIAE-100, which weighs roughly 416 tons after machining, is mainly consisting of 4 pairs of sector magnets, 4 return yokes, top/bottom yoke, central plug, and shimming bars. It falls into the category of large-scale high precision device,

  18. Electronic Learning Systems in Hong Kong Business Organizations: A Study of Early and Late Adopters

    Science.gov (United States)

    Chan, Simon C. H.; Ngai, Eric W. T.

    2012-01-01

    Based on the diffusion of innovation theory (E. M. Rogers, 1983, 1995), the authors examined the antecedents of the adoption of electronic learning (e-learning) systems by using a time-based assessment model (R. C. Beatty, J. P. Shim, & M. C. Jones, 2001), which classified adopters into categories upon point in time when adopting e-learning…

  19. 78 FR 31389 - Airworthiness Directives; The Boeing Company Airplanes

    Science.gov (United States)

    2013-05-24

    ..., and (4) Will not have a significant economic impact, positive or negative, on a substantial number of... reinforcement of the cross beam of the forward cargo door, which terminates the existing repetitive inspections... repaired, and a one-time inspection of the reinforcement angle for excessive shimming or fastener...

  20. 77 FR 50407 - Airworthiness Directives; The Boeing Company Airplanes

    Science.gov (United States)

    2012-08-21

    ... economic impact, positive or negative, on a substantial number of small entities under the criteria of the... modification of the outboard radius of the lower corners of the door frame and reinforcement of the cross beam..., and a one-time inspection of the reinforcement angle for excessive shimming or fastener pull-up,...

  1. Transitioning Intelligence to Embedded Platforms

    Science.gov (United States)

    2007-11-01

    ESCHER Research Institute. Portions of the system are currently available through the CRRCSim and MNAV Autopilot releases. This release will include...acknowledge the generous contributions of Dr. David H.C. Shim, Boeing Phantom Works and the ESCHER Institute, particularly the technical assistance provided

  2. Recent progress on technologies and applications of transgenic ...

    African Journals Online (AJOL)

    USER

    2010-06-14

    Jun 14, 2010 ... applications (Scott and Lois, 2005; van de Lavoir et al.,. 2006b ..... Kwon MS, Koo BC, Choi BR, Lee HT, Kim YH, Ryu WS, Shim H, Kim JH,. Kim NH, Kim .... Severino C, David FD, Shrikant D, Jennifer HD, Lynae G, Edward LH,.

  3. Placement of field probes for stabilization of breathing-induced B0-fluctuations in the brain

    DEFF Research Database (Denmark)

    Andersen, Mads; Madsen, Kristoffer H; Hanson, L.G.

    2015-01-01

    Introduction: B0-fluctuations induced by breathing and body motion lead to artifacts for certain brain imaging sequences at ultra-high field (7T). A promising solution is to monitor the B0-fluctuations during the scan using external field probes, and update the shim currents in real-time (1...

  4. Permanent Magnet with Very Low Field Gradient (0.1G/mm) for NMR Spectroscopy

    Science.gov (United States)

    Ilic, Ognjen; Issadore, David; Hunt, Tom; Westervelt, Robert

    2007-03-01

    Nuclear Magnetic Resonance (NMR) is a powerful analytical tool for obtaining chemical, physical and structural information. To produce the uniform fields required, NMR experiments typically employ large, expensive electromagnets and shimming coils. We have developed a small permanent magnet with an iron yoke that produces a field of ˜10 kG with gradient CCNE.

  5. Comparison Of The Direct Costs, Length Of Recovery, And Incidence Of Post Operative Anti Emetic Use After Anesthesia Induction With Propofol Or A 1:1 Mixture Of Thiopental And Propofol

    Science.gov (United States)

    1999-10-01

    Caucasian pediatric patients (Runcie, Mackenzie, Arthur, & Morton, 1993). Propofol is associated with a feeling of well being during recovery (Jakobsson...showed the least hemodynamic changes in pediatric patients versus induction with thiopental, propofol , or halothane followed by halothane maintenance...Blagrove, McCallum, & Bromley, 1997). Chinese pediatric patients experienced significantly greater drops in blood pressure with propofol (Aun, Sung

  6. The Japan-China Amity Delegation Written Report Association for Science, Technology and Economics, Inc.

    Science.gov (United States)

    1981-03-12

    Industry Model (meters) Bureau .............. Process Supervisor Hsu Ben Chi ......... Machine Institute .......... Technician Liu Hsiang ...Fei Sho ......... Tientsin Computer Center ....... Technician Tung Do Kin ......... Tientsin Computer Center ....... Technician Hsiang Ko Shu...Research Lab) Ryu Shan (Shanghai Computer Research Lab) Sung Pat Chuan )(Shanghai Wireless Chang Go Jo ) Electronics Number 13 Factory) Including

  7. Hajhosseini et al., Afr J Tradit Complement Altern Med. (2013) 10(6 ...

    African Journals Online (AJOL)

    cadewumi

    acid group that received 5mg/rat (gavage) (n=10), electromagnetic fields (EMF) group ..... Kuo, C. F., Su, J. D., Chiu, C. H., Peng, C. C., Chang, C. H., Sung, T. Y., Huang, ... Zhang, J. J., Wang, Y. L, Feng, X. B., Song, X. D., and Liu, W. B. (2011).

  8. Saving the Spiritual for Your Students

    Science.gov (United States)

    Small, Kathryn

    2009-01-01

    Spirituals are religious folk songs that were created and sung by enslaved African Americans to express the emotions and thoughts of a people in bondage. The spiritual conveyed deep religious convictions and the desire for freedom brought on by two centuries' worth of oppression, as slavery was legal in the United States from approximately 1650…

  9. ROK Young Friendship Envoys Delegation in China

    Institute of Scientific and Technical Information of China (English)

    Xu; Yan

    2015-01-01

    At the invitation of the CPAFFC,Mr.Kim Sung-yup,former Council Member of the Korean Foundation(KF),led a 120-member delegation of the Republic of Korea"Yo u n g Friendship Envoys"comprising young entrepreneurs,artists,deaf-mutes and high school students on a visit to Beijing,Hebei and Zhejiang from October 26 to

  10. The Korean Question: Is There a Role for Forward-Based American Forces in a Unified Korea?

    Science.gov (United States)

    2003-01-01

    Kongdan Oh and Ralph Hassig’s North Korea: Through the Looking Glass and North Korea After Kim Il Sung edited by Thomas Henriksen and Jongryn Mo...Kongdan and Ralph C. Hassig. North Korea through the Looking Glass . Washington D.C.: Brookings Institution Press, 2000. Olsen, Edward A. U.S. Policy and

  11. The Economic Implications of Korean Unification

    Science.gov (United States)

    2002-06-01

    Kim Il Sung: Continuity Or Change? (Stanford, CA: Hoover Institution Press, 1997), 75-78. 101 Ralph C Hassig, (et. al.). North Korea through the Looking Glass (Washington...Princeton University Press, 2002) Hassig, Ralph C. (et. al.). North Korea through the Looking Glass (Washington, DC: The Brookings Institute, 2000

  12. "I'd Rather Wear a Turban than a Rose": A Case Study of the Ethics of Chanting

    Science.gov (United States)

    Jones, Carwyn; Fleming, Scott

    2007-01-01

    In this paper we explore the moral status of a chant overheard during the Wales versus England (men's) rugby union international match in February, 2005. The specific chant, sung by Welsh supporters at their English counterparts, was: "I'd rather wear a turban than a rose." Specifically, we examine: whether the chant is offensive; whether the…

  13. Measurement of characteristic leap interval between chest and falsetto registers

    NARCIS (Netherlands)

    Miller, DG; Svec, JG; Schutte, HK

    2002-01-01

    A markedly smaller time constant distinguishes a chest-falsetto leap from the more usual execution of a sung interval by muscular adjustments in the length and tension of the vocal folds. The features of such a chest-falsetto leap are examined in detail with respect to F-0, peak-to-peak amplitude of

  14. Keeping Timbre in Mind: Working Memory for Complex Sounds that Can't Be Verbalized

    Science.gov (United States)

    Golubock, Jason L.; Janata, Petr

    2013-01-01

    Properties of auditory working memory for sounds that lack strong semantic associations and are not readily verbalized or sung are poorly understood. We investigated auditory working memory capacity for lists containing 2-6 easily discriminable abstract sounds synthesized within a constrained timbral space, at delays of 1-6 s (Experiment 1), and…

  15. Zeitgemäße Betrachtungen

    DEFF Research Database (Denmark)

    Wucherpfennig, Wolf

    die Auflösung lebendiger kultureller Tradition. Der Niedergang von Bildung und politischer Kultur legt einen Vergleich zwischen der Gegenwart des American Empire nebst Verbündeten mit der Spätzeit des Imperium Romanum nahe. Es zeigt sich: Der Fortschritt ist eine Illusion, und der Versuch, das reine...

  16. La Marimba y el joven Pluma de Quetzal: una leyenda chiapaneca. (The Marimba and the Young Man, Pluma de Quetzal: A Chiapaneca Legend.)

    Science.gov (United States)

    Marquez, Jerry

    The illustrated book is about the legend of Pluma de Quetzal and the marimba. The story, which takes place in the Mexican state of Chiapas, tells how the woodcutters who lived in the area would sit around the fire talking and singing every night. Sung by tired voices, their songs had no happy music. Instead of happiness and hope, they expressed…

  17. Hymns

    DEFF Research Database (Denmark)

    Lech, Marcel Lysgaard

    2017-01-01

    Hymns as sung prayers to deities. Just as these were frequent in the everyday life of an Athenian, hymns occur frequently in Old Comedy. In its use of hymns comedy reflects this everyday practice, but the comic playwrights also use hymns light-heartedly for comic purposes such as parody. Hymns...

  18. From Ancient to Modern: The role of astronomy as a cultural experience

    Science.gov (United States)

    Austin, Margaret

    2011-06-01

    With these sung words a grandmother, a teacher of the Waitaha Maori people of New Zealand, sets in motion the telling of the great patterns of journeys. These journeys to and from distant shores are still in the minds and memories of the elder grandparent teachers of the Waitaha people.

  19. The influence of gibberellic acid and paclobutrazol on induction of ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-07-20

    Jul 20, 2009 ... The effects of exogenous gibberellic acid (GA3) and paclobutrazol on ... These medicinal properties are due to .... 1962), 3% (w/v) sucrose, 0.7% (w/v) agar and 100 mg l-1 myo- .... somatic embryos it is enhanced by the addition of unico- .... Cheng JCH, Robey J, Sung ZR, de Vries SC, Ogas J (2004).

  20. The Power of Song

    DEFF Research Database (Denmark)

    Sørensen, Bent

    of periods in American history, but none is better represented than the Depression Era of the 1930s. Songs such as “Seven Cent Cotton and Forty Cent Meat” (which we hear in Steinbeck’s Grapes of Wrath was sung in the impromptu camp communities that sprung up along the road to California for the migrant...

  1. Ein wissensbasiertes Framework zur flexiblen Konfiguration von AAL-Umgebungen

    OpenAIRE

    2015-01-01

    Die Herausforderung in Ambient Assisted Living (AAL) ist es, die vielen heterogenen Komponenten in der AAL-Umgebung geeignet zu arrangieren, um auf die individuellen, schnell wechselnden Bedürfnisse der Nutzer einzugehen. Die Lösung ist ein semantisches Konfigurationsframework. Dieses Framework beinhaltet geeignete Prozesse, Werkzeuge sowie einen ontologiebasierten Austausch, Wiederverwendung und Automatisierung der Informationen zwischen den einzelnen Integrationsschritten.

  2. The 12 Ways to Health Holiday Song

    Centers for Disease Control (CDC) Podcasts

    2007-12-14

    This song (sung to the tune of The Twelve Days of Christmas) describes how to stay safe and healthy during the holidays and all year long.  Created: 12/14/2007 by CDC Office of Women's Health.   Date Released: 12/23/2007.

  3. SYNTHESIS, CHARACTERIZATION AND BIOACTIVITY Zn2+, Cu2+ ...

    African Journals Online (AJOL)

    ray powder diffraction analysis of complexes (2) and (3) indicate that the ... wastewater and catalytic processes [15]. furthermore, azo compounds have an increased ...... Dong Koo, K.; Lee, C.S.; Sung Koh, J.; Kim, G.T. Design and synthesis of ...

  4. Using a Radical-Derived Character E-Learning Platform to Increase Learner Knowledge of Chinese Characters

    Science.gov (United States)

    Chen, Hsueh-Chih; Hsu, Chih-Chun; Chang, Li-Yun; Lin, Yu-Chi; Chang, Kuo-En; Sung, Yao-Ting

    2013-01-01

    The present study is aimed at investigating the effect of a radical-derived Chinese character teaching strategy on enhancing Chinese as a Foreign Language (CFL) learners' Chinese orthographic awareness. An e-learning teaching platform, based on statistical data from the Chinese Orthography Database Explorer (Chen, Chang, Chou, Sung, & Chang,…

  5. A Study of Auditory Preferences in Nonhandicapped Infants and Infants with Down's Syndrome.

    Science.gov (United States)

    Glenn, Sheila M.; And Others

    1981-01-01

    Eleven infants with Down's syndrome and 10 of 11 nonhandicapped infants operated an automatic device which enabled them to choose to listen to nursery rhymes sung or played on musical instruments. Both groups preferred the singing, and the Down's Syndrome infants had much longer response durations for the more complex auditory stimuli. (Author/DB)

  6. Singing Video Games May Help Improve Pitch-Matching Accuracy

    Science.gov (United States)

    Paney, Andrew S.

    2015-01-01

    The purpose of this study was to investigate the effect of singing video games on the pitch-matching skills of undergraduate students. Popular games like "Rock Band" and "Karaoke Revolutions" rate players' singing based on the correctness of the frequency of their sung response. Players are motivated to improve their…

  7. Collaborative Platform for DFM

    Science.gov (United States)

    2007-12-20

    pleasure of working with or learning from Alejandro De La Fuente, Chung Sung, Zheng Guo, Liang-Teck Pang, Paul Friedberg, Louis Alarcon, Qingguo Liu, Yu...simulation” SPIE, vol.5756, no.38, 2005 24 Ortolland, C. Orain, S. Rosa , J. Morin, P. Arnaud, F. Woo, M. Poncet, A. Stolk, P

  8. Word Intelligibility in Multi-voice Singing: The Influence of Chorus Size.

    Science.gov (United States)

    Condit-Schultz, Nathaniel; Huron, David

    2017-01-01

    This study investigated how the intelligibility of sung words is influenced by the number of singers in a choral music style. The study used repeated measures factorial. One hundred forty-nine participants listened to recordings of spoken and sung English words and attempted to identify the words. Each stimuli word was sung or spoken in sync by either one, four, eight, sixteen, or twenty-seven members of a high-quality Soprano Alto Tenor Bass (SATB) choir. In general, single-voice word recognition was higher than multi-voice word recognition in the sung condition. However, the difference between four concurrent singers and the full choir was negligible; that is, reduced intelligibility with multiple singers shows little sensitivity to the number of singers. The principal effect of voice density on intelligibility is found to occur with coda consonants-a result consistent with the importance many choral conductors attribute to coordinating word offsets. In particular, the plosives /b/, /d/, /g/, and /p/ are easily confused. Coda liquids (/l/,/r/) were also found to be a source of confusion. Finally, an increasing density of voices appears to have a facilitating effect for the coda nasal /m/. Groups of four or more choral singers do appear to be less intelligible than single singers, although the observed effect is modest. However, increasing the number of singers in a choral texture beyond four singers does not appear to further degrade intelligibility. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  9. Singing Video Games May Help Improve Pitch-Matching Accuracy

    Science.gov (United States)

    Paney, Andrew S.

    2015-01-01

    The purpose of this study was to investigate the effect of singing video games on the pitch-matching skills of undergraduate students. Popular games like "Rock Band" and "Karaoke Revolutions" rate players' singing based on the correctness of the frequency of their sung response. Players are motivated to improve their…

  10. Comparison of vocal tract formants in singing and nonperiodic phonation

    NARCIS (Netherlands)

    Miller, DG; Sulter, AM; Schutte, HK; Wolf, RF

    The skilled use of nonperiodic phonation techniques in combination with spectrum analysis has been proposed here as a practical method for locating formant frequencies in the singing voice. The study addresses the question of the degree of similarity between sung phonations and their nonperiodic

  11. The impact of music on learning and consolidation of novel words.

    Science.gov (United States)

    Tamminen, Jakke; Rastle, Kathleen; Darby, Jess; Lucas, Rebecca; Williamson, Victoria J

    2017-01-01

    Music can be a powerful mnemonic device, as shown by a body of literature demonstrating that listening to text sung to a familiar melody results in better memory for the words compared to conditions where they are spoken. Furthermore, patients with a range of memory impairments appear to be able to form new declarative memories when they are encoded in the form of lyrics in a song, while unable to remember similar materials after hearing them in the spoken modality. Whether music facilitates the acquisition of completely new information, such as new vocabulary, remains unknown. Here we report three experiments in which adult participants learned novel words in the spoken or sung modality. While we found no benefit of musical presentation on free recall or recognition memory of novel words, novel words learned in the sung modality were more strongly integrated in the mental lexicon compared to words learned in the spoken modality. This advantage for the sung words was only present when the training melody was familiar. The impact of musical presentation on learning therefore appears to extend beyond episodic memory and can be reflected in the emergence and properties of new lexical representations.

  12. Assessment of the Effects of Air-Sea-Land Interaction Processes on the Intensity and Impact of Modelled and Observed Coastal Extratropical Cyclones

    Science.gov (United States)

    2011-09-08

    estimated insured value of U.S. coastal properties. June Bengtsson, L. M., K. I. Hodges , M. Esch, N. Keenlyside, L. Kornbleuh, J.-J. Luo, and T...Russell, Makiko~Sato, Drew T. Shindell, Peter H. Stone, Shan Sun, Nick Tausnev, Duane Thresher, Mao-Sung Yao 2005. Present day atmospheric simulations

  13. Online Responses to a Multilingual Super Bowl Ad: Is "America the Beautiful" by Any Other Language Still America, the Beautiful?

    Science.gov (United States)

    Hoffman, Brooke Y.

    2016-01-01

    On 2 February 2014, an advertisement entitled "It's Beautiful" debuted during Super Bowl XLVIII, which was watched by 111.5 million people in the USA. The Coca-Cola advertisement portrayed people of various ethnicities and was accompanied by "America the Beautiful" sung in nine languages. Using critical discourse analysis, I…

  14. Basics about Babies' Brain Development = Los basicos del desarrollo del cerebro.

    Science.gov (United States)

    Southeastern Regional Vision for Education (SERVE), Tallahassee, FL.

    This brochure for parents, in English- and Spanish-language versions, provides facts about infants' brains and offers suggestions for parents to help their baby's development by providing experiences to stimulate neural development. The facts are: (1) a baby's brain needs many different experiences to be nourished, such as being talked or sung to…

  15. Umformtechnik Handbuch für Industrie und Wissenschaft

    CERN Document Server

    Lange, Kurt

    2013-01-01

    Der verständlich aufbereitete Stoff behandelt Fließkurven und Fließortkurven, die Ermittlung von Verfahrenswerten durch Messen, die Grundlagen der Werkzeugmaschinen zum Umformen sowie die Arbeitsgenauigkeit. Die Informationen sind ausführlich genug für die selbständige Lösung nicht zu spezieller Probleme. Umfassende Literaturangaben erleichtern die Einarbeitung in Spezialgebiete.

  16. Cerebellar Patients Demonstrate Preserved Implicit Knowledge of Association Strengths in Musical Sequences

    Science.gov (United States)

    Tillmann, Barbara; Justus, Timothy; Bigand, Emmanuel

    2008-01-01

    Recent findings suggest the involvement of the cerebellum in perceptual and cognitive tasks. Our study investigated whether cerebellar patients show musical priming based on implicit knowledge of tonal-harmonic music. Participants performed speeded phoneme identification on sung target chords, which were either related or less-related to prime…

  17. La Marimba y el joven Pluma de Quetzal: una leyenda chiapaneca. (The Marimba and the Young Man, Pluma de Quetzal: A Chiapaneca Legend.)

    Science.gov (United States)

    Marquez, Jerry

    The illustrated book is about the legend of Pluma de Quetzal and the marimba. The story, which takes place in the Mexican state of Chiapas, tells how the woodcutters who lived in the area would sit around the fire talking and singing every night. Sung by tired voices, their songs had no happy music. Instead of happiness and hope, they expressed…

  18. NON-GRAMMATICAL APOPHONY IN ENGLISH.

    Science.gov (United States)

    WESCOTT, ROGER W.

    AN APOPHONE MAY BE DEFINED GENERALLY AS A POLYSYLLABIC VOWEL SEQUENCE SUCH THAT EACH CONTAINED VOWEL IS LOWER OR MORE RETRACTED THAN THE VOWEL WHICH PRECEDES IT --"SING, SANG, SUNG," AND "CLINK, CLANK, CLUNK" ARE EXAMPLES IN ENGLISH. FOR NEARLY EVERY CASE OF GRAMMATICAL APOPHONY IN ENGLISH THERE IS A NON-GRAMMATICAL (YET…

  19. Psychosoziale Beratung im Internet als Problemintervention bei Jugendlichen

    Directory of Open Access Journals (Sweden)

    Julia Brummel

    2008-10-01

    Full Text Available Im Rahmen einer Diplomarbeit an der Universität Bielefeld im Fach Soziologie wurde anhand einer quantitativ-empirischen Fragebogenstudie untersucht, inwieweit die Beratung im Internet dem Umgang Jugendlicher mit ihren Problemen und ihren Methoden der Problemlösung entspricht. Der vorliegende Text stellt eine kurze Zusammenfassung der Herangehensweise an diese Untersuchung und die Ergebnisse der Studie dar.

  20. Interview with Mr.WAN Wai Loi of Paciflc Textiles

    Institute of Scientific and Technical Information of China (English)

    Vicky; Sung; Textile; Journalist

    2010-01-01

    Leading knitted fabric manufacturer Pacific Textiles headquartered in Hong Kong saw its sales,revenue,profits and market share increased during the global economic downturn.How did they do it? Machinery played a role in the success formula as Vicky Sung found out in a recent interview with its chairman and executive director,Mr.WAN Wai Loi.

  1. Qualities of a voice emeritus

    NARCIS (Netherlands)

    Bloothooft, Gerrit; Pabon, Peter

    2004-01-01

    The effects of vocal ageing are investigated in a professional mezzo-soprano singer, for which the phonetogram, and 45 vowels, each sung at fundamental frequencies of 220, 392, and 659 Hz, were recorded at the age of 52 and 74 years. The comparison demonstrates a serious loss in the vocal range, dyn

  2. Probiotics as an alternative control strategy against avian coccidiosis Probiotics as an alternative control strategy against avian coccidiosis

    Science.gov (United States)

    Coccidiosis is caused by several species of Eimeria, intestinal protozoan parasites which cost the poultry industry > $ 3.0 billion annually in losses worldwide. Hyun S. Lillehoj and Sung-Hyen Lee at the Animal & Natural Resources Institute, USDA-ARS, have demonstrated the effectiveness of commercia...

  3. Miniaturized Retrodirective Arrays for a Nanosatellite Platform

    Science.gov (United States)

    2012-01-01

    128-134, Jan.2006. [13] T. Brabetz, V. F. Fusco, and S. Karode, "Balanced subharmonic mixers for retrodirective- array applications," IEEE Trans...Murakami, J.D. Roque, S. S. Sung, G. S. Shiroma, R. Y. Miyamoto, and W. A. Shi- roma, "A quadruple subharmonic phase-conjugating array for secure

  4. The use of network analysis to study complex animal communication systems

    DEFF Research Database (Denmark)

    Weiss, Michael; Hultsch, Henrike; Adam, Iris

    2014-01-01

    The singing of song birds can formcomplex signal systems comprised of numerous subunits sung with distinct combinatorial properties that have been described as syntax-like. This complexity has inspired inquiries into similarities of bird song to human language; but the quantitative analysis and d...

  5. HOTEL INFORMATION

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Crowne Plaza Park View Wuzhou Beijing Lee Soo Sung, former Prime Minister of the Republic of Korea, is warmly welcomed by Ilja Poepper, Resident Manager of Crowne Plaza Park View Wuzhou Beijing, upon his arrival at the hotel on December 22, 2005.

  6. AFRREV IJAH, Vol.2 (1) February, 2012

    African Journals Online (AJOL)

    user

    Key Word: Music in Burials; Akwa Oke-Nwanyi; Sociological of Music ... conscientize the society and guide the people towards the right path of life. .... The song is normally sung by Akwa Oke-Nwaanyi at the burial of children or youths who are ...

  7. SDP落地中国面临两大挑战

    Institute of Scientific and Technical Information of China (English)

    李新苗

    2009-01-01

    @@ 近日,韩国下一代移动通信论坛(NGMC)秘书长SHIN SUNG-MOON表示,SDP是一个非常好的概念,作为服务提供平台,能够支持不同的业务.也由此,SDP再度引起本刊的关注.

  8. Ennekuulmatud loomalaulud / Panda Bear (Noah Lennox) ; interv. Siim Nestor

    Index Scriptorium Estoniae

    Panda Bear (Noah Lennox)

    2006-01-01

    Intervjuu eksperimentaalset popmuusikat viljeleva ameerika ansambli Animal Collective laulja Panda Bear'iga (kontsert 4. juulil Tallinnas Lillepaviljonis). Heliplaatidest: "Spirit They're Gone, Spirit They've Vanished", "Danse Manatee", "Hollindagain", "Campfire Songs", "Here Comes the Indian", "Sung Tongs", "Feels"

  9. The Effect of Text Translation on Perceived Musical Tension in Debussy's "Noel des enfants qui n'ont plus de maisons"

    Science.gov (United States)

    Hackworth, Rhonda S.; Fredrickson, William E.

    2010-01-01

    The primary focus of the present study was to investigate the effect participants' (N = 100) knowledge of a text translation may have on their perceived musical tension while listening to a piece of choral music sung in another language. When examining the graphs that show the group mean responses of the participants, control (without text…

  10. Deck Yourself with Flu Protection Song

    Centers for Disease Control (CDC) Podcasts

    2009-12-22

    This song (sung to the tune of Deck the Halls) describes actions you can take to protect yourself and others from the flu. Sing along!  Created: 12/22/2009 by National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID), Division of Global Migration and Quarantine (DGMQ).   Date Released: 12/22/2009.

  11. Ennekuulmatud loomalaulud / Panda Bear (Noah Lennox) ; interv. Siim Nestor

    Index Scriptorium Estoniae

    Panda Bear (Noah Lennox)

    2006-01-01

    Intervjuu eksperimentaalset popmuusikat viljeleva ameerika ansambli Animal Collective laulja Panda Bear'iga (kontsert 4. juulil Tallinnas Lillepaviljonis). Heliplaatidest: "Spirit They're Gone, Spirit They've Vanished", "Danse Manatee", "Hollindagain", "Campfire Songs", "Here Comes the Indian", "Sung Tongs", "Feels"

  12. Infants' Memory for Musical Performances

    Science.gov (United States)

    Volkova, Anna; Trehub, Sandra E.; Schellenberg, E. Glenn

    2006-01-01

    We evaluated 6- and 7-month-olds' preference and memory for expressive recordings of sung lullabies. In Experiment 1, both age groups preferred lower-pitched to higher-pitched renditions of unfamiliar lullabies. In Experiment 2, infants were tested after 2 weeks of daily exposure to a lullaby at one pitch level. Seven-month-olds listened…

  13. Methodische Ansätze und Entwicklungen interkultureller Forschung in der Wirtschaftspsychologie am Beispiel organisationaler Einstellungen

    OpenAIRE

    Müller, Karsten; Kempen, Regina; Straatmann, Tammo

    2012-01-01

    Der folgende Beitrag beleuchtet methodische Herausforderungen der interkulturellen Wirtschaftspsychologie am Beispiel der Forschung zu organisationalen Einstellungen. Zunächst wird dabei die Forschung im Bereich der interkulturellen Wirtschaftspsychologie innerhalb der Extrempole einer holistischen bzw. einer analytischen Forschungsperspektive verortet. Im Anschluss daran werden spezifische, mit der analytischen Perspektive assoziierte Herausforderungen der Forschung, sowie mögliche Lösung...

  14. Folgebewertung im vorratsvermögen - Fallstudie zur Vorgehensweise nach IFSR und HGB

    DEFF Research Database (Denmark)

    Quick, Reiner; Warming-Rasmussen, Bent

    2013-01-01

    über die wichstigsten Normen zur Folgebeweriung nach IFSR und HGB sowie zu deren Auslegung. Es schliessen sich ein Fallbeispiel und ein Vorschlag zu dessen Lösung an, in dessen Mittelpunkt sinkende Zeitwerte, die Frage des für die Folgebewerunng relevanten Markts und das Zuschreibungsgebot stehen....

  15. Basics about Babies' Brain Development = Los basicos del desarrollo del cerebro.

    Science.gov (United States)

    Southeastern Regional Vision for Education (SERVE), Tallahassee, FL.

    This brochure for parents, in English- and Spanish-language versions, provides facts about infants' brains and offers suggestions for parents to help their baby's development by providing experiences to stimulate neural development. The facts are: (1) a baby's brain needs many different experiences to be nourished, such as being talked or sung to…

  16. Charge density study with the Maximum Entropy Method on model data of silicon. A search for non-nuclear attractors

    NARCIS (Netherlands)

    Vries, de R.Y.; Briels, W.J.; Feil, D.; Velde, te G.; Baerends, E.J.

    1996-01-01

    1990 Sakata and Sato applied the maximum entropy method (MEM) to a set of structure factors measured earlier by Saka and Kato with the Pendellösung method. They found the presence of non-nuclear attractors, i.e., maxima in the density between two bonded atoms. We applied the MEM to a limited set of

  17. Gender Ambivalence and The Expression of Passions in the Performances of Early Roman Cantatas by Castrati and Female Singers

    DEFF Research Database (Denmark)

    Jeanneret, Christine

    2013-01-01

    Solo singing is associated with the expression of passions during the 17th century. Cantatas were sung by women as well as castrati, playing an ambivalent game on gender, eroticism, and passions. Contemporary testimonies of these performances juxtaposed with the medical theory of the humors shows...

  18. Reference: 414 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 414 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u16832621i Jayasekara... 11 1255-62 16832621 2006 Nov Plant cell reports Jayasekaran Kandakumar|Kim Kyung-Nam|Ok Sung Han|Shin Jeong Sheop|Vivekanandan Munusamy

  19. A Drum's Trans-Atlantic Journey from Africa to the Americas and ...

    African Journals Online (AJOL)

    2010-12-08

    Long .... by the use of the drum were in Pidgin English, sung by workers of multiethnic origin ...... Universidad Nacional de Educación a Distancia, 1999. ... cuba. colección de Artículos. .... Investigaciones Científicas (CSIC), Madrid.

  20. Die Auswahl Der Richtigen E-Commerce-Software Für Das Eigene Unternehmen - Anwendung Des AHP-Modells(Şirketiniz İçin Doğru E-Ticaret Yazılım Seçimi – AHP-Model Uygulaması

    Directory of Open Access Journals (Sweden)

    Kemal YAMAN

    2012-01-01

    Full Text Available Die Auswahl der richtigen eBusiness-Software-Lösung hat für das eBusiness-Geschäft von Unternehmen eine große Bedeutung. Das bedeutet, dass die Unternehmen eines kompetentes, effizientes, flexibles und starkes Softwarepakets bedürfen. Dafür müssen sie eine ausführliche Analyse des passenden Softwarepaketes aus dem wirtschaftlichen Aspekt ausführen. Denn eine solche Softwarelösung soll einem Unternehmen ermöglichen, ihre Produkte und Dienstleistungen problemlos online anbieten zu können. Es wird festgestellt, dass sie Auswahl solcher Softwarepakete sorgfältig durchgeführt werden müssen, da diese unterschiedliche Stärken bzw. Eigenschaften aufweisen. Zum Beispiel hat eine Lösung sehr gute Marketing-Tools, die andere jedoch Sicherheits- oder Flexibilität-Tools. Im ersten Teil der Arbeit wird auf die Bedeutung der Auswahl einer eBusiness-Lösung eingegangen und es werden dabei die relevanten Eigenschaften von Softwarelösungen sowie ihre Relevanz für den Unternehmensgeschäftserfolg geschildert. Im zweiten Teil wird der Analytic Hierarchy Process dargestellt, bei dem das Entscheidungsproblem in kleinere Teilaufgaben aufgelöst werden, die dann zu lösen sind. Schließlich werden im dritten Teil in einer abschließenden Zusammenfassung die Ergebnisse und die Schlussfolgerungen geschildert.

  1. On degree phrases and result clauses

    NARCIS (Netherlands)

    Rijkhoek, Paulien Dea

    1998-01-01

    This dissertation consists of two parts, one on degree phrases and one on result clauses. Sentence (1) below exemplifies a result clause construction: (1) Zij had zo mooi gezongen dat het publiek er stil van was she has so beautifully sang that the audience there silent of was ‘She had sung so beaut

  2. Uudised : Anu Tali debüüt Hesseni raadios

    Index Scriptorium Estoniae

    2007-01-01

    28. septembril juhatab dirigent Anu Tali Frankfurdis esmakordselt Hesseni Raadio Sümfooniaorkestrit Hesseni Ringhäälingu saalis. Ettekandel Tõnu Kõrvitsa teos"Sung into the Wind", Shostakovitshi 9. sümfoonia ja Beethoveni 5. klaverikontsert (solist Herbert Schuch)

  3. The Year 2012: South Korea’s Resumption of Wartime Operational Control

    Science.gov (United States)

    2011-05-01

    Winter Olympics controversy virulently incited the Korean nation after Korea’s speed skater Kim Dong-sung was disquali- fied on a technicality and a U.S...athlete won the gold medal ; the 2002 U.S. tactical vehicle accident which killed two Korean school girls led to massive and pro- longed

  4. The Microhistory of Anti-Japanese Speech Acts

    Directory of Open Access Journals (Sweden)

    Andre Schmid

    2013-12-01

    Full Text Available "Readings from Asia" highlights significant recent scholarship published in Chinese, Korean, Japanese, and Vietnamese, in order to bring it to the attention of a wider, international readership. This issue of Cross-Currents features a review by Andre Schmid (University of Toronto of Jung Byung Wook's new book titled Puron yŏlchŏn: Mich’in saenggaggi paetsok esŏ naonda [The biographies of rebellious people in colonial Korea]. Schmid finds Jung's microhistorical approach very effective in recreating a sense of the political dangers during the wartime colonial period and in revealing the paranoia of the colonial state. The case studies presented in the book, Schmid claims, "are not about nationalist movements or intellectuals’ proindependence essays, but moments involving unorganized, ordinary people who because of their actions drew the scrutiny of the state’s repressive apparatus."

  5. Class and ethnicity in the global market for organs: the case of Korean cinema.

    Science.gov (United States)

    Garden, Rebecca; Yoo Murphree, Hyon Joo

    2007-12-01

    While organ transplantation has been established in the medical imagination since the 1960s, this technology is currently undergoing a popular re-imagination in the era of global capitalism. As transplantation procedures have become routine in medical centers in non-Western and developing nations and as organ sales and transplant tourism become increasingly common, organs that function as a material resource increasingly derive from subaltern bodies. This essay explores this development as represented in Korean filmmaker Park Chan-wook's 2002 Sympathy for Mr. Vengeance, focusing on the ethnic and class characteristics of the global market in organs and possible modes of counter-logic to transplant technologies and related ethical discourses.

  6. A method to improve the B0 homogeneity of the heart in vivo.

    Science.gov (United States)

    Jaffer, F A; Wen, H; Balaban, R S; Wolff, S D

    1996-09-01

    A homogeneous static (B0) magnetic field is required for many NMR experiments such as echo planar imaging, localized spectroscopy, and spiral scan imaging. Although semi-automated techniques have been described to improve the B0 field homogeneity, none has been applied to the in vivo heart. The acquisition of cardiac field maps is complicated by motion, blood flow, and chemical shift artifact from epicardial fat. To overcome these problems, an ungated three-dimensional (3D) chemical shift image (CSI) was collected to generate a time and motion-averaged B0 field map. B0 heterogeneity in the heart was minimized by using a previous algorithm that solves for the optimal shim coil currents for an input field map, using up to third-order current-bounded shims (1). The method improved the B0 homogenelty of the heart in all 11 normal volunteers studied. After application of the algorithm to the unshimmed cardiac field maps, the standard deviation of proton frequency decreased by 43%, the magnitude 1H spectral linewidth decreased by 24%, and the peak-peak gradient decreased by 35%. Simulations of the high-order (second- and third-order) shims in B0 field correction of the heart show that high order shims are important, resulting for nearly half of the improvement in homogeneity for several subjects. The T2* of the left ventricular anterior wall before and after field correction was determined at 4.0 Tesis. Finally, results show that cardiac shimming is of benefit in cardiac 31P NMR spectroscopy and cardiac echo planar imaging.

  7. Music-based memory enhancement in Alzheimer's disease: promise and limitations.

    Science.gov (United States)

    Simmons-Stern, Nicholas R; Deason, Rebecca G; Brandler, Brian J; Frustace, Bruno S; O'Connor, Maureen K; Ally, Brandon A; Budson, Andrew E

    2012-12-01

    In a previous study (Simmons-Stern, Budson & Ally, 2010), we found that patients with Alzheimer's disease (AD) better recognized visually presented lyrics when the lyrics were also sung rather than spoken at encoding. The present study sought to further investigate the effects of music on memory in patients with AD by making the content of the song lyrics relevant for the daily life of an older adult and by examining how musical encoding alters several different aspects of episodic memory. Patients with AD and healthy older adults studied visually presented novel song lyrics related to instrumental activities of daily living (IADL) that were accompanied by either a sung or a spoken recording. Overall, participants performed better on a memory test of general lyric content for lyrics that were studied sung as compared to spoken. However, on a memory test of specific lyric content, participants performed equally well for sung and spoken lyrics. We interpret these results in terms of a dual-process model of recognition memory such that the general content questions represent a familiarity-based representation that is preferentially sensitive to enhancement via music, while the specific content questions represent a recollection-based representation unaided by musical encoding. Additionally, in a test of basic recognition memory for the audio stimuli, patients with AD demonstrated equal discrimination for sung and spoken stimuli. We propose that the perceptual distinctiveness of musical stimuli enhanced metamemorial awareness in AD patients via a non-selective distinctiveness heuristic, thereby reducing false recognition while at the same time reducing true recognition and eliminating the mnemonic benefit of music. These results are discussed in the context of potential music-based memory enhancement interventions for the care of patients with AD.

  8. Music-Based Memory Enhancement in Alzheimer’s Disease: Promise and Limitations

    Science.gov (United States)

    Simmons-Stern, Nicholas R.; Deason, Rebecca G.; Brandler, Brian J.; Frustace, Bruno S.; O’Connor, Maureen K.; Ally, Brandon A.; Budson, Andrew E.

    2012-01-01

    In a previous study (Simmons-Stern, Budson, & Ally 2010), we found that patients with Alzheimer’s disease (AD) better recognized visually presented lyrics when the lyrics were also sung rather than spoken at encoding. The present study sought to further investigate the effects of music on memory in patients with AD by making the content of the song lyrics relevant for the daily life of an older adult and by examining how musical encoding alters several different aspects of episodic memory. Patients with AD and healthy older adults studied visually presented novel song lyrics related to instrumental activities of daily living (IADL) that were accompanied by either a sung or a spoken recording. Overall, participants performed better on a memory test of general lyric content for lyrics that were studied sung as compared to spoken. However, on a memory test of specific lyric content, participants performed equally well for sung and spoken lyrics. We interpret these results in terms of a dual-process model of recognition memory such that the general content questions represent a familiarity-based representation that is preferentially sensitive to enhancement via music, while the specific content questions represent a recollection-based representation unaided by musical encoding. Additionally, in a test of basic recognition memory for the audio stimuli, patients with AD demonstrated equal discrimination for sung and spoken stimuli. We propose that the perceptual distinctiveness of musical stimuli enhanced metamemorial awareness in AD patients via a non-selective distinctiveness heuristic, thereby reducing false recognition while at the same time reducing true recognition and eliminating the mnemonic benefit of music. These results are discussed in the context of potential music-based memory enhancement interventions for the care of patients with AD. PMID:23000133

  9. Runāto un dziedāto latviešu valodas patskaņu [ī], [ā] un [ū] kvalitātes salīdzinājums

    Directory of Open Access Journals (Sweden)

    Juris Grigorjevs

    2011-12-01

    Full Text Available THE COMPARISON OF THE QUALITY OF SPOKEN AND SUNG LATVIAN VOWELS [i:], [ɑ:] AND [u:]SummaryNumerous studies in phonetics have attempted to investigate the differences between spoken and sung vowels. The majority of these studies dealt with the articulatory and acoustic changes observed in opera singers, however, there were several studies which compared the production of vowels by opera and choir singers. This article presents a pilot study performed on the basis of an audio material acquired from one informant (mezzo-soprano, where the acoustic quality of spoken Latvian vowels [i:], [ɑ:] and [u:] has been compared to the quality of the same vowels sung in isolation (in octave of La Minor, i.e., from A3 to A4, labeled in this article as octave of Do Major because of cer­tain reasons and sung in the verse of a song. It was observed during the current study that the transition from the chest register to the middle register had taken place between C4 and D4, which is normally observed in mezzo-sopranos. To make the interpretation of the influence of a variable pitch on the vowel formant pattern easier, all Latvian vowels were plotted in the psycho-physical F2ʹ/F1 (bark plane. The observed changes in F1 re­flect the tuning of the first vocal resonance to the pitch that is acquired by a jaw opening. Gradual larynx lowering and lip rounding can be the reason for lowering of F2ʹ value for [i:], reduced lip rounding — for increasing of F2ʹ value for [u:], but rising of the tongue tip — for increasing of F2ʹ value for [ɑ:]. The observed changes question the assumption that vowels in singing preserve their quality except for very low and very high registers (the octave under investigation does not belong to such registers. The minor differences observed in vowels sung in the verse from vowels sung in isolation can be explained by the influence of immediate phonetic context. It can be concluded that the data obtained in this investigation, in

  10. Investigating excitation-dependent and fringe-field effects of electromagnet and permanent-magnet phase shifters for a crossed undulator

    Science.gov (United States)

    Chung, Ting-Yi; Yang, Chih-Sheng; Chu, Yun-Liang; Lin, Fu-Yuan; Jan, Jyh-Chyuan; Hwang, Ching-Shiang

    2017-04-01

    To enhance the flux density or to control polarization, a phase shifter was designed and used to modulate the phase matching between segmented undulators. A larger hysteresis loop causes, however, a repeatability issue in the phase matching; the fringe field of the phase shifter creates an extra magnetic-field error. The design of the phase shifter must therefore minimize the hysteresis loop and fringe field to maintain the phases exact and to ignore the crosstalk effect. Two critical issues are the hysteresis-loop problem and the fringe-field effect, which determine the radiation performance and the stability of the ring. To investigate these issues, a phase shifter was constructed to operate in accordance with electromagnetic- and permanent-type magnets; the results from the field measurements and shims are discussed here. The shimming algorithm and a compact permanent-magnet phase shifter that eliminates the issues are also presented.

  11. Experimental verification of a deep drawing tool system for adaptive blank holder pressure distribution

    DEFF Research Database (Denmark)

    Tommerup, Søren; Endelt, Benny Ørtoft

    2012-01-01

    In deep drawing, the strain path in the blank during the forming process can be significantly affected by application of temporal and spatial variation of the blank holder force. In this study, an active tool system capable of controlling the distribution of the blank holder force is presented...... which can be integrated into existing stacked deep drawing tools without need for modification of the press. A working system is presented consisting of a controller, designated volume displacement cavity pressure supply units and a shimming plate. It is applied to the deep drawing of a rectangular...... geometry using a conventional stacked tool design. The shimming plate is used to support the blank holder plate, and has four integrated hydraulic cavities in which the pressure can be controlled individually whereby a controlled deflection of the blank holder plate is achieved analogous...

  12. Method of making hermetic seals for hermetic terminal assemblies

    Science.gov (United States)

    Hsu, John S.; Marlino, Laura D.; Ayers, Curtis W.

    2010-04-13

    This invention teaches methods of making a hermetic terminal assembly comprising the steps of: inserting temporary stops, shims and jigs on the bottom face of a terminal assembly thereby blocking assembly core open passageways; mounting the terminal assembly inside a vacuum chamber using a temporary assembly perimeter seal and flange or threaded assembly interfaces; mixing a seal admixture and hardener in a mixer conveyor to form a polymer seal material; conveying the polymer seal material into a polymer reservoir; feeding the polymer seal material from the reservoir through a polymer outlet valve and at least one polymer outlet tube into the terminal assembly core thereby filling interstitial spaces in the core adjacent to service conduits, temporary stop, and the terminal assembly casing; drying the polymer seal material at room temperature thereby hermetically sealing the core of the terminal assembly; removing the terminal assembly from the vacuum chamber, and; removing the temporary stops, shims.

  13. Design of the superconducting magnet for 9.4 Tesla whole-body magnetic resonance imaging

    Science.gov (United States)

    Li, Y.; Wang, Q.; Dai, Y.; Ni, Z.; Zhu, X.; Li, L.; Zhao, B.; Chen, S.

    2017-02-01

    A superconducting magnet for 9.4 Tesla whole-body magnetic resonance imaging is designed and fabricated in Institute of Electrical Engineering, Chinese Academy of Sciences. In this paper, the electromagnetic design methods of the main coils and compensating coils are presented. Sensitivity analysis is performed for all superconducting coils. The design of the superconducting shimming coils is also presented and the design of electromagnetic decoupling of the Z2 coils from the main coils is introduced. Stress and strain analysis with both averaged and detailed models is performed with finite element method. A quench simulation code with anisotropic continuum model and control volume method is developed by us and is verified by experimental study. By means of the quench simulation code, the quench protection system for the 9.4 T magnet is designed for the main coils, the compensating coils and the shimming coils. The magnet cryostat design with zero helium boiling-off technology is also introduced.

  14. Design, construction and characterization of the compact ultrafast terahertz free-electron laser undulator

    Indian Academy of Sciences (India)

    B Biswas; V Kumar; S Chouksey; S Krishnagopal

    2008-12-01

    A compact ultrafast terahertz (CUTE) free-electron laser (FEL) is being developed at the Raja Ramanna Centre for Advanced Technology (RRCAT), Indore. The undulator required for the CUTE-FEL has recently been developed. We have designed, built and characterized a variable gap, 5 cm period, 2.5 m long pure permanent magnet undulator in two identical segments. The tolerable error in the magnetic field was 1% in rms, and we have measured it to be 0.7%. The obtained rms phase shake is around 2°. To ensure that the trajectories do not have an exit error in position or angle, corrector coils have been designed. Shimming coils have been applied for both the undulator segments to reduce the amplitude of the betatron oscillations in the vertical trajectory. Details of novel corrector coils and soft iron shims are given and their performance is discussed.

  15. Placement of field probes for stabilization of breathing-induced B0-fluctuations in the brain

    DEFF Research Database (Denmark)

    Andersen, Mads; Madsen, Kristoffer H.; Hanson, Lars G.;

    ). It is a fundamental challenge, however, that the B0 measurements are spatially sparse (e.g. 16 probes), and performed outside the brain. Typically, the field is modelled by a linear combination of the spatial shim fields that the scanner can produce (such as spherical harmonics up to 3rd order), and the coefficients......Introduction: B0-fluctuations induced by breathing and body motion lead to artifacts for certain brain imaging sequences at ultra-high field (7T). A promising solution is to monitor the B0-fluctuations during the scan using external field probes, and update the shim currents in real-time (1...... for these spatial terms are determined by least square fitting to the field probe measurements. The probes must be placed carefully to ensure that the spherical harmonics can be distinguished using these few samples, and they must be placed close to the head so that the spatial field model is valid and to have good...

  16. Thermal breeder fuel enrichment zoning

    Science.gov (United States)

    Capossela, Harry J.; Dwyer, Joseph R.; Luce, Robert G.; McCoy, Daniel F.; Merriman, Floyd C.

    1992-01-01

    A method and apparatus for improving the performance of a thermal breeder reactor having regions of higher than average moderator concentration are disclosed. The fuel modules of the reactor core contain at least two different types of fuel elements, a high enrichment fuel element and a low enrichment fuel element. The two types of fuel elements are arranged in the fuel module with the low enrichment fuel elements located between the high moderator regions and the high enrichment fuel elements. Preferably, shim rods made of a fertile material are provided in selective regions for controlling the reactivity of the reactor by movement of the shim rods into and out of the reactor core. The moderation of neutrons adjacent the high enrichment fuel elements is preferably minimized as by reducing the spacing of the high enrichment fuel elements and/or using a moderator having a reduced moderating effect.

  17. Placement of field probes for stabilization of breathing-induced B0-fluctuations in the brain

    DEFF Research Database (Denmark)

    Andersen, Mads; Madsen, Kristoffer H; Hanson, L.G.

    2015-01-01

    Introduction: B0-fluctuations induced by breathing and body motion lead to artifacts for certain brain imaging sequences at ultra-high field (7T). A promising solution is to monitor the B0-fluctuations during the scan using external field probes, and update the shim currents in real-time (1). It ...... SNR. Here, we provide a simulation of breathing-induced B0-fluctuations inside and around the head and use this simulated field to test different sets of probe positions. We also formulate two optimization problems to guide placement of the field probes.......Introduction: B0-fluctuations induced by breathing and body motion lead to artifacts for certain brain imaging sequences at ultra-high field (7T). A promising solution is to monitor the B0-fluctuations during the scan using external field probes, and update the shim currents in real-time (1...

  18. Replication of nanopits and nanopillars by roll-to-roll extrusion coating using a structured cooling roll

    DEFF Research Database (Denmark)

    Murthy, Swathi; Pranov, Henrik; Pedersen, Henrik Chresten

    2016-01-01

    This paper investigates a novel, very high throughput, roll-to-roll (R2R) process for nanostructuring of polymer foils, called R2R extrusion coating. It has the potential to accelerate the integration of nanostructured materials in consumer products for a variety of applications, including optical......, technical, and functional surfaces and devices. In roll-to-roll extrusion coating, a molten polymer film is extruded through a flat die forming a melt curtain, and then laminated onto a carrier foil. The lamination occurs as the melt curtain is pressed between a cooling roller and a counter roller....... By mounting a nanostructured metal shim on the surface of the cooling roller, the relief structure from the shim can be replicated onto a thermoplastic foil. Among the benefits of P oil, the process are availability of a wide range of commercial extruders, off-the-shelf extrusion grade polymers, functional...

  19. Auswirkungen des Urin-pH auf das Ballonvolumen bei Dauerkathetern

    Directory of Open Access Journals (Sweden)

    Pannek J

    2007-01-01

    Full Text Available Einleitung: Eine häufige Komplikation der transurethralen oder suprapubischen Dauerkatheterversorgung ist die Dislokation durch eine insuffiziente Katheterblockung. Die Auswirkungen des Urin-pH auf das Ballonvolumen sind dabei bisher nicht untersucht. Methodik: In einer In-vitro-Studie wurden Dauerkatheter aus Silikon und Latex mit entweder 10%iger Glyzerinlösung oder mit 0,9%iger NaCl-Lösung geblockt und 14 Tage bei verschiedenen pH-Werten in künstlichem Urin gelagert. Nach diesem Zeitraum wurde die rückgewonnene Flüssigkeit aus dem Katheterballon gemessen. Ergebnisse: Bei allen Katheterballons wurde eine Reduktion des Ballonvolumens von maximal 20 % festgestellt. Weder das verwendete Füllmedium noch das Kathetermaterial hatte signifikante Auswirkungen auf das Ausmaß der Volumenänderung. Schlußfolgerung: Die Änderung des Urin-pH führt nicht zu Volumenverschiebungen im Katheterballon.

  20. ’n Lied moet klink om gehoor te word ... : Faktore wat die resepsie van kerkliedere kan beïnvloed

    Directory of Open Access Journals (Sweden)

    Elsabé Kloppers

    2013-01-01

    Full Text Available A hymn must be sung to be heard ... : Aspects that could influence the reception of hymns and psalms. The most recent official hymnal in Afrikaans, Liedboek van die Kerk, was taken into use in 2001. Some hymns and psalms were immediately sung with enthusiasm whereas others remained unused, which is true especially for many of the metrical psalms. The most prominent reason for not singing some hymns or psalms is that they are unknown – text as well as tune. It is, however, often assumed that the reason why hymns and psalms are unknown is primarily because their tunes would be too difficult to sing. The role of the text and other aspects are not taken into account sufficiently. In this article, these one-sided views regarding the tunes are challenged, and it is argued that there could be many other reasons why hymns and psalms are not used.

  1. Fiber hodoscope in the COMPASS experiment for the detection of particle tracks within the primary beam

    CERN Document Server

    Nahle, Ole Jens; Hinterberger, F.

    2002-01-01

    Für das COMPASS-Experiment am CERN wurden Hodoskope aus szintillierenden Fasern entwickelt, getestet und in das Experiment integriert. Die Spurrekonstruktion im oder in unmittelbarer Nähe des Primärstrahls stellt hohe Anforderungen in Bezug auf Ratenfestigkeit, Zeitauflösung, Nachweiseffizienz und Strahlenhärte aller Detektorkomponenten. Vorstudien zur Eignung von szintillierenden Fasern und Lichtleitern in Verbindung mit Vielkanal-Photomultipliern führten zur Fertigung eines Prototyps, der bei nominalen Bedingungen intensiv getestet wurde. Mit den hieraus gewonnen Erfahrungen wurden insgesamt vier Faserhodoskope realisiert und im Rahmen des COMPASS-Experiments betrieben. Hierbei wurde eine intrinsische Detektoreffizienz von nahezu 100% erreicht. Mit einer Zeitauflösung von etwa 450 ps bei gleichzeitig geringen Treffermultiplizitäten ist eine eindeutige Rekonstruktion von Teilchenspuren auch bei Strahlraten von bis zu 100 MHz möglich. Im Dauerbetrieb über 250 Tage während zweier Strahlzeiten zeigte...

  2. Wooden models of an AA quadrupole between bending magnets

    CERN Multimedia

    1978-01-01

    At two points in the AA lattice, a quadrupole (QDN, defocusing, narrow) was tightly wedged between two bending magnets (BST, short, wide). This picture of wooden models lets one imagine the strong interaction between their magnetic fields. There was no way one could calculate with the necessary accuracy the magnetic effects and their consequences for the machine optics. The necessary corrections were made after measurements with a circulating beam, in a tedious iterative procedure, with corrrection coils and shims.

  3. Nanocrystal quantum dots

    CERN Document Server

    Klimov, Victor I

    2010-01-01

    ""Soft"" Chemical Synthesis and Manipulation of Semiconductor Nanocrystals, J.A. Hollingsworth and V.I. Klimov Electronic Structure in Semiconductor Nanocrystals: Optical Experiment, D.J. NorrisFine Structure and Polarization Properties of Band-Edge Excitons in Semiconductor Nanocrystals, A.L. EfrosIntraband Spectroscopy and Dynamics of Colloidal Semiconductor Quantum Dots, P. Guyot-Sionnest, M. Shim, and C. WangMultiexciton Phenomena in Semiconductor Nanocrystals, V.I. KlimovOptical Dynamics in Single Semiconductor Quantum Do

  4. A Multidisciplinary Algorithm for the 3-D Design Optimization of Transonic Axial Compressor Blades

    Science.gov (United States)

    2002-06-01

    1, pp. 49-54, 1995 19. Puterbaugh, S. L., W. W. Copenhaver , C. Hah, and A. J. Wennerstrom, A Three- Dimensional Shock Loss Model Applied to an...Aerospace Sciences Meeting and Exhibit - Reno, Nevada, January 2002 23. Chung, J., J. Shim, and K. D. Lee, Design of 3-D Transonic Compressor Blades...Using Numerical Optimization, AIAA Paper 2000-0227, Presented at the 38th Aerospace Sciences Meeting and Exhibit – Reno, Nevada, January 2000 24

  5. New Methodology For Use in Rotating Field Nuclear MagneticResonance

    Energy Technology Data Exchange (ETDEWEB)

    Jachmann, Rebecca C. [Univ. of California, Berkeley, CA (United States)

    2007-01-01

    High-resolution NMR spectra of samples with anisotropicbroadening are simplified to their isotropic spectra by fast rotation ofthe sample at the magic angle 54.7 circ. This dissertation concerns thedevelopment of novel Nuclear Magnetic Resonance (NMR) methodologies basedwhich would rotate the magnetic field instead of the sample, rotatingfield NMR. It provides an over of the NMR concepts, procedures, andexperiments needed to understand the methodologies that will be used forrotating field NMR. A simple two-dimensional shimming method based onharmonic corrector rings which can provide arbitrary multiple ordershimming corrections were developed for rotating field systems, but couldbe used in shimming other systems as well. Those results demonstrate, forexample, that quadrupolar order shimming improves the linewidth by up toan order of magnitude. An additional order of magnitude reduction is inprinciple achievable by utilizing this shimming method for z-gradientcorrection and higher order xy gradients. A specialized pulse sequencefor the rotating field NMR experiment is under development. The pulsesequence allows for spinning away from the magic angle and spinningslower than the anisotropic broadening. This pulse sequence is acombination of the projected magic angle spinning (p-MAS) and magic angleturning (MAT) pulse sequences. This will be useful to rotating field NMRbecause there are limits on how fast a field can be spun and spin at themagic angle is difficult. One of the goals of this project is forrotating field NMR to be used on biological systems. The p-MAS pulsesequence was successfully tested on bovine tissue samples which suggeststhat it will be a viable methodology to use in a rotating field set up. Aside experiment on steering magnetic particle by MRI gradients was alsocarried out. Some movement was seen in these experiment, but for totalcontrol over steering further experiments would need to bedone.

  6. New Methodology For Use in Rotating Field Nuclear MagneticResonance

    Energy Technology Data Exchange (ETDEWEB)

    Jachmann, Rebecca C. [Univ. of California, Berkeley, CA (United States)

    2007-05-18

    High-resolution NMR spectra of samples with anisotropicbroadening are simplified to their isotropic spectra by fast rotation ofthe sample at the magic angle 54.7 circ. This dissertation concerns thedevelopment of novel Nuclear Magnetic Resonance (NMR) methodologies basedwhich would rotate the magnetic field instead of the sample, rotatingfield NMR. It provides an over of the NMR concepts, procedures, andexperiments needed to understand the methodologies that will be used forrotating field NMR. A simple two-dimensional shimming method based onharmonic corrector rings which can provide arbitrary multiple ordershimming corrections were developed for rotating field systems, but couldbe used in shimming other systems as well. Those results demonstrate, forexample, that quadrupolar order shimming improves the linewidth by up toan order of magnitude. An additional order of magnitude reduction is inprinciple achievable by utilizing this shimming method for z-gradientcorrection and higher order xy gradients. A specialized pulse sequencefor the rotating field NMR experiment is under development. The pulsesequence allows for spinning away from the magic angle and spinningslower than the anisotropic broadening. This pulse sequence is acombination of the projected magic angle spinning (p-MAS) and magic angleturning (MAT) pulse sequences. This will be useful to rotating field NMRbecause there are limits on how fast a field can be spun and spin at themagic angle is difficult. One of the goals of this project is forrotating field NMR to be used on biological systems. The p-MAS pulsesequence was successfully tested on bovine tissue samples which suggeststhat it will be a viable methodology to use in a rotating field set up. Aside experiment on steering magnetic particle by MRI gradients was alsocarried out. Some movement was seen in these experiment, but for totalcontrol over steering further experiments would need to bedone.

  7. The development and testing of ceramic components in piston engines. Final report

    Energy Technology Data Exchange (ETDEWEB)

    McEntire, B.J. [Norton Co., Northboro, MA (United States). Advanced Ceramics Div.; Willis, R.W.; Southam, R.E. [TRW, Inc., Cleveland, OH (United States)

    1994-10-01

    Within the past 10--15 years, ceramic hardware has been fabricated and tested in a number of piston engine applications including valves, piston pins, roller followers, tappet shims, and other wear components. It has been shown that, with proper design and installation, ceramics improve performance, fuel economy, and wear and corrosion resistance. These results have been obtained using rig and road tests on both stock and race engines. Selected summaries of these tests are presented in this review paper.

  8. Development of a miniature permanent magnetic circuit for nuclear magnetic resonance chip

    Science.gov (United States)

    Lu, Rongsheng; Yi, Hong; Wu, Weiping; Ni, Zhonghua

    2013-07-01

    The existing researches of miniature magnetic circuits focus on the single-sided permanent magnetic circuits and the Halbach permanent magnetic circuits. In the single-sided permanent magnetic circuits, the magnetic flux density is always very low in the work region. In the Halbach permanent magnetic circuits, there are always great difficulties in the manufacturing and assembly process. The static magnetic flux density required for nuclear magnetic resonance(NMR) chip is analyzed based on the signal noise ratio(SNR) calculation model, and then a miniature C-shaped permanent magnetic circuit is designed as the required magnetic flux density. Based on Kirchhoff's law and magnetic flux refraction principle, the concept of a single shimming ring is proposed to improve the performance of the designed magnetic circuit. Using the finite element method, a comparative calculation is conducted. The calculation results demonstrate that the magnetic circuit improved with a single shimming has higher magnetic flux density and better magnetic field homogeneity than the one improved with no shimming ring or double shimming rings. The proposed magnetic circuit is manufactured and its experimental test platform is also built. The magnetic flux density measured in the work region is 0.7 T, which is well coincided with the theoretical design. The spatial variation of the magnetic field is within the range of the instrument error. At last, the temperature dependence of the magnetic flux density produced by the proposed magnetic circuit is investigated through both theoretical analysis and experimental study, and a linear functional model is obtained. The proposed research is crucial for solving the problem in the application of NMR-chip under different environmental temperatures.

  9. The technological future of 7 T MRI hardware.

    Science.gov (United States)

    Webb, A G; Van de Moortele, P F

    2016-09-01

    In this article we present our projections of future hardware developments on 7 T human MRI systems. These include compact cryogen-light magnets, improved gradient performance, integrated RF-receive and direct current shimming coil arrays, new RF technology with adaptive impedance matching, patient-specific specific absorption rate estimation and monitoring, and increased integration of physiological monitoring systems. Copyright © 2015 John Wiley & Sons, Ltd.

  10. Design of the Main Magnets of the SESAME Storage Ring

    CERN Document Server

    Milanese, A; Shehab, M

    2014-01-01

    This paper describes the magnetic design of the main magnets of the SESAME storage ring. The 16 dipoles are combined function bending magnets, designed with an adjustable iron shimming scheme. The 64 quadrupoles are of two different lengths and strengths. The 64 sextupoles are optimized for field quality in 3D without end pole chamfers and they include additional coils to provide a horizontal/vertical dipole and a skew quadrupole terms.

  11. Narzissmus und Subjektivität : psychoanalytische Betrachtungen eines zeitgemäßen Erscheinungsbildes unter Berücksichtigung der zugrunde liegenden Dialektik zwischen Gesellschaft und Individuum

    OpenAIRE

    Bornhauser,Niklas

    2005-01-01

    Der Narzissmus ist ein zentraler Begriff psychoanalytischer Praxis und Theoriebildung. Vorwiegend klinisch orientierte Begriffsbestimmungen des Narzissmus tendieren naturgemäß dazu, gesellschaftliche, kulturelle oder erkenntniswissenschaftliche Mutationen nicht ausreichend zu berücksichtigen. Die Beachtung des kulturellen und sozialen Kontexts der Emergenz des Narzissmus sowie die Berücksichtigung des zugrunde liegenden epochalen Wandels, die Ablösung der Moderne durch die einsetzende Postmod...

  12. Data acquisition, event building and signal reconstruction for Compton camera imaging

    OpenAIRE

    Nurdan, Kivanc

    2006-01-01

    Nurdan, Kıvanç Die Compton-Camera ist ein neues Detektorsystem zur bildlichen Darstellung von radioaktiven Markierungssubstanzen im Bereich der Gammastrahlung, das prinzipiell eine besonders gute Ortsauflösung und hohe Empfindlichkeit liefern kann. Die ist von grosser Bedeutung für die moderne bio-medizinische Forschung oder für darauf basierende diagnostische Verfahren. Dafür ist ein neues Konzept einer software-basierten Koinzidenzmessung entwickelt worden, das auf den b...

  13. Uygur Muqam: Miracle of Music

    Institute of Scientific and Technical Information of China (English)

    郑茜; 天粒

    2005-01-01

    The Uyghur 12 Muqam is so large in scale and so comphcated in rendition that no nval can oe found in Tnis world.It consists of 360 sung poetry, stories, dance tunes and instrumental sections. Some of the lyrics of the Muqam are drawn from 44 great classic poets and folk poetry, totaling 4,492 lines of words. The Twelve Muqam each consists of suites of fixed melodic sequences and order. To sing a complete Muqam takes around 24 hours.

  14. A Hybrid Time Synchronization Algorithm Based on Broadcast Sequencing for Wireless Sensor Networks

    Science.gov (United States)

    2014-09-01

    sequence per the flow charts detailed in Figures 43–45 located in Appendix A. The input 1 in Figure 12 is a recursive step from some of the...SYNCHRONIZATION ALGORITHM BASED ON BROADCAST SEQUENCING FOR WIRELESS SENSOR NETWORKS by Sung C. Park September 2014 Thesis Co-Advisors...REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE A HYBRID TIME SYNCHRONIZATION ALGORITHM BASED ON BROADCAST SEQUENCING FOR

  15. Analyse und Bewertung von Naturgefahren als Grundlage für ein nachhaltiges Naturgefahrenmanagement in Gebirgssystemen SO-Kasachstans am Beispiel des Ile-Alatau

    OpenAIRE

    2007-01-01

    Den Fragen der Erarbeitung des Naturgefahrenmanagements in Gebirgsystemen SO-Kasachstans und in den Ländern des Zentralasiens insgesamt wurde bisher keine gebührende Aufmerksamkeit zuteil. Die Naturkatastrophen der letzten Jahrzehnte sowie die Erfahrung mit Maßnahmen zum Schutz des Ile-Alatau vor Naturgefahren haben gezeigt, dass die Lösung dieser Probleme für die weitere nachhaltige Entwicklung dieser Region von erstrangiger Bedeutung ist. In dieser Arbeit wurde vom Autor umfangreiches Ma...

  16. From linear algebraic systems to elimination graphs and harmonic functions

    OpenAIRE

    Luce, Robert

    2014-01-01

    In dieser Dissertation werden Fragestellungen behandelt, die sich aus der Lösung von schwachbesetzten, linearen Gleichungssystemen ergeben. So wird zunächst untersucht, wie das bekannte Minimum-Fill Problem in der schwachbesetzen Cholesky-Faktorisierung mit dem Problem der Minimierung der arithmetischen Operationen zur Berechnung eben dieser zusammenhängt. Hierzu wird eine Klasse von Graphen konstruiert, für welche keine Eliminationsordung für die Faktorisierung existiert, welche für diese be...

  17. Evolutionäre Strategien und multitome Optimierung

    OpenAIRE

    Rosé, Helge

    1998-01-01

    Für die erfolgreiche Lösung eines Optimierungsproblems ist die Wahl der verwendeten Suchstrategie von entscheidender Bedeutung. Die vorliegende Arbeit untersucht die Kriterien dieser Wahl. Dabei stellen sich drei grundlegende Fragen: Welche Strategien der Optimierung eines gegebenen Problems existieren überhaupt, und was für Eigenschaften besitzen sie? Wodurch wird der Charakter eines Optimierungsproblems bestimmt, und gibt es Klassen ähnlicher Probleme? Besteht eine Verbindung zwischen den E...

  18. Die Effekte des künstlichen Sauerstoffträgers Diaspirin crosslinked hemoglobin auf die Mikrozirkulation des Pankreas

    OpenAIRE

    Dobschütz, Ernst Felix Wilhelm von

    2002-01-01

    Der Einsatz von allogenen Blutkonserven bei hämorrhagischem Schock ist durch den hohen logistischen Aufwand der Kreuzproben und die Knappheit von Spenderblut limitiert. Deshalb ist die Erforschung eines künstlichen Blutersatzstoffs ein internationales Ziel der chirurgischen und intensivmedizinischen Forschung. Ziel dieser experimentellen Studie war die Analyse der Mikrozirkulation des Pankreas der Ratte nach intravenöser Applikation der modifizierten Hämoglobinlösung Diaspirin ...

  19. Anwendung von Hydroxyethylstärke 200/0.5 (Infukoll HES 10%) bei gesunden Pferden und Pferden mit Kolik oder akuter Kolitis

    OpenAIRE

    Rieckhoff, Karin

    2004-01-01

    In einer kontrollierten Studie an gesunden Pferden wurde die Pharmakokinetik von Infukoll HES 10% untersucht und dessen klinische Wirksamkeit in unterschiedlichen Dosierungen mit der von isotoner und hypertoner NaCl-Lösung verglichen. In einer darauffolgenden prospektiven klinischen Untersuchung an Pferden mit akuter Kolitis oder Ileus konnte die Wirksamkeit des Plasmaexpanders am Pferdepatienten dokumentiert werden. Die Versuchsgruppe, bestehend aus 6 Warmblut-Stuten, nahm an 5 Versuchsreihe...

  20. Sustaining the Heritage: Assessing the Aesthetics of Verbal Symbolisation and Signifaction in Idanre Orature

    Directory of Open Access Journals (Sweden)

    N. Akingbe

    2012-12-01

    Full Text Available This study shows how oral poetry permeates the culture and activities of Africans. In almost all African communities, there are poetic expressions such that poems are sung to express mother/father/child’s emotional state for and at every occasion. These include marriage, age grade celebration, departure or separation from one another, death, farming, hunting, trading and religious celebrations. The paper x-rays cultural configuration with the application of cultural theory to delineate societal transformation.

  1. A Case Analysis Explaining the Main Factors that Contribute to ROK’s Decision Making in Procurement of Defense Articles

    Science.gov (United States)

    2008-05-01

    theories represent a “pattern” of interconnected thoughts or parts linked to a whole ( Lincoln and Guba , 1985). Neuman provides additional information...South Korea, 2005. Lincoln , Y. S., & Guba , E. G. Proposals that work: A Guide for Planning Dissertations and Grant Proposals (2nd ed.), Newbury Park...2005. Bak, Sung Il. A study on the Dominion of Dokdo . Mokpo marine college, Chunnam South Korea, 2005. Bloomfield, Lincoln P. Jr. “Status of U.S

  2. Trading Freshness for Performance in Distributed Systems

    Science.gov (United States)

    2014-12-01

    Facebook , Fusion-IO, Google, Hewlett-Packard, Hitachi, Huawei, IBM, Intel, LSI, Microsoft, NEC Labs, NetApp, Oracle, Panasas, Riverbed, Sam- sung, Seagate...in machine learning algorithms. These algorithms have applications in data mining, web search, genomics, advertising , and mapping. In the second case...to drive various decision support applications, such as sales or advertisement analytics. Generally speaking, the data genera- tion is continuous

  3. Konzeptionelle Untersuchungen für die HADES-Driftkammern am Prototyp 0

    OpenAIRE

    1997-01-01

    Mit dem Dileptonenspektrometer HADES (High Acceptance Di-Electron Spectrometer) sollen Dielektronen, die bei zentralen Au+Au-Kollisionen der Energie von bis zu 2 GeV/u entstehen, spektroskopiert werden. Zentrale Detektorkomponente ist ein Magnetspektrometer, bestehend aus einem toroidalem Magnetfeld und 24 Driftkammern, die zur Orts- und Impulsbestimmung durch Ablenkung im Magnetfeld verwendet werden. Hohe Raten minimal ionisierender Teilchen, eine Massenauflösung von 1% im Massenbereich von ...

  4. Comment on ''Fabrication methods for low-Pt-loading electrocatalysts in proton exchange membrane fuel cell systems'' [J.-H. Wee, K.-Y. Lee, S.H. Kim, J. Power Sources 165 (2007) 667-677

    Energy Technology Data Exchange (ETDEWEB)

    Gruber, D. [Department of Micro Systems Technology, Hamburg University of Technology, D-21071 Hamburg (Germany)

    2007-11-08

    Glow discharge sputter deposition of metals like Pt or other materials is around for decades. One of the many advantages of this process is - certain prerequisites given - the good adhesion of the sputtered layers due to the physical assisted deposition. Sputter deposition is attributed poor adherence by Wee et al. [Jung-Ho Wee, Kwan-Young Lee, Sung Hyun Kim, J. Power Sources 165 (2007) 667-677], which asks for some comments. (author)

  5. Targeting the I-Kappa-B Kinase Epsilon (IKKe) for Breast Cancer Therapy

    Science.gov (United States)

    2009-09-01

    inhibits growth and invasiveness of breast cancer cells. (under review, submitted to Breast Cancer Research) Appendix II. Bin Qin, Ravi S. Shukla , Kun...inhibitor of kappaB kinase pathways in oncogenic initiation and progression. Oncogene 2006, 25(51):6817-6830. 21. Sung B, Pandey MK , Nakajima Y, Nishida...Bin Qin, Ravi S. Shukla , Kun Cheng* Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte

  6. Inhibition of Breast Cancer Progression by Blocking Heterocellular Contact Between Epithelial Cells and Fibroblasts

    Science.gov (United States)

    2013-04-01

    International Association for Breast Cancer Research/Breakthrough Breast Cancer Conference, Manchester, UK, 2012, Oral presentation. • Sung K E, Pelhke...20), 14906–14915. 22 C. Kuperwasser, T. Chavarria, M. Wu, G. Magrane, J. W. Gray, L. Carey, A. Richardson and R. A. Weinberg, Reconstruction of...DCIS and require autophagy for survival. PLoS ONE 5: e10240. doi:10.1371/journal.pone.0010240. 20.$Burstein HJ, Polyak K, Wong JS, Lester SC, Kaelin

  7. The Growing Relationship Between South Korea and China: Consequences for North Korea

    Science.gov (United States)

    2006-03-01

    2001). And Sung-Jin Yang, "Korea Storms Chinas Handset Market ," Asia Computer Weekly (Aug 19 2002): 1. 40 Snyder, "Economic Interests Uber Alles...SUPPLEMENTARY NOTES The views expressed in this thesis are those of the author and do not reflect the official policy or position of the Department...Korea’s position toward this growing relationship and the implications of it for Pyongyang. Finally, this thesis analyzes the implications for Japan

  8. Schnelles semi-quantitatives Screening auf Antibiotikarückstände in Fleisch

    OpenAIRE

    2016-01-01

    In dieser Arbeit wurde der ursprünglich für den Antibiotika-Nachweis in Milch entwickelte Biosensor MCR3 für das Screening von Fleischproben auf Hemmstoffrückstände in Fleisch evaluiert, adaptiert, validiert und mit hemmstoffhaltigen Proben aus der Routinepraxis erfolgreich getestet. Die orientierende Evaluierung der Antikörper-basierten Einzelnachweise zeigte, dass in Pufferlösung alle implementierten Antibiotika (Penicillin G, Cloxacillin, Nafcillin, Cephapirin, Ceftiofur, Gentamicin, Ne...

  9. Synthesis and microstructural characterization of metals@MOF-5

    OpenAIRE

    Schröder, Felicitas

    2008-01-01

    Die Arbeit befasst sich mit der Synthese und mikrostrukturellen Charakterisierung von metallischen, katalytisch relevanten Nanopartikeln im metallorganischen Netzwerk MOF-5, mit Schwerpunkt auf die vorherrschenden Wirt-Gast Wechselwirkungen. Ausgehend von [Ru(cod)(cot)]@MOF-5 konnten Ru Nanopartikel in MOF-5 hydrogenolytisch erhalten werden, dabei verhielten sich die Partikel ähnlich wie in Lösung stabilisierte Ru Kolloide und zeigten sehr geringe Wechselwirkungen mit der Trägerma...

  10. Chinese Dream——Concert in Commemoration of 115th Birth Anniversary of Premier Zhou Enlai Held

    Institute of Scientific and Technical Information of China (English)

    Our; Staff; Reporter

    2013-01-01

    <正>The theme song of the film The Founding of a Republic sung by male vocalists Dai Yuqiang and Wei Song reverberated in the Opera Hall at the National Center for the Performing Arts on the `evening of March 14. It marked the start of the concert in commemoration of the 115th anniversary of the birth of Premier Zhou Enlai, with "Chinese Dream" as the theme.

  11. Phonatory Strategies of Male Vocalists in Singing Diatonic Scales With Various Dynamic Shapings.

    Science.gov (United States)

    Vurma, Allan

    2017-03-01

    This work aimed to investigate glottal adduction in the case of the singing of diatonic D major ascending scales with different dynamic shapings on vowel [a:] by 10 classically trained male singers. The parameters obtained by inverse filtering-closed quotient (CQ), normalized amplitude quotient (NAQ), and the level difference between the first two partials of the glottal flow waveform spectrum (H1-H2)-all indicated statistically significant systematic changes when singers sang (1) with habitual dynamics without intentional dynamic changes; (2) with sempre crescendo from piano to forte; and (3) with sempre diminuendo from forte to piano. Adduction on average was lower if the tone with the same pitch was sung piano compared with when it was sung forte. The piano tones with the limit of one and the same dynamic task were sung with lower adduction on average compared with one octave higher or lower tones sung forte, although here the agreement between different parameters was poorer and the individual variability was greater. There was only a moderate negative correlation between CQ and NAQ (r = -0.41) but a strong negative correlation between CQ and H1-H2 (r = -0.8). CQ showed a moderate positive correlation with sound level but no significant correlation with pitch. NAQ showed a strong and significant positive correlation with pitch but not with sound level (except when it was calculated only at constant pitch). Some of the most experienced singers used quite high glottal adduction levels, questioning the concept of whether flow phonation is always the favorite classical style. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  12. The physics of singing vibrato

    Science.gov (United States)

    Michel, Christa R.; Ruiz, Michael J.

    2017-07-01

    A spectrogram of a singer’s vibrato presents a striking way to introduce students to frequency, Fourier spectra, and modulation. Vibrato is discussed from the perspectives of the physicist and the musician. A dramatic spectrogram is included where coauthor soprano Michel suppresses her vibrato so that acoustical characteristics can be compared to the same note sung with vibrato. A video (Ruiz 2017 Video: vibrato http://mjtruiz.com/ped/vibrato/) is provided of this demonstration.

  13. The Folk Literature of the Sephardic Jews Digital Library

    Directory of Open Access Journals (Sweden)

    Bruce Rosenstock

    2013-10-01

    Full Text Available The essay describes the digital library containing audio files and transcriptions of Hispanic ballads and other oral literary genres sung by Sephardic Jewish informants and collected initially by the late Professors Samuel Armistead and Joseph Silverman, later joined by the ethnomusicologist Israel Katz. Beginning in 1957 their fieldwork was conducted over several decades in North America, North Africa, Israel, Greece, and the Balkans.

  14. Cerebellar patients demonstrate preserved implicit knowledge of association strengths in musical sequences

    OpenAIRE

    Tillmann, Barbara; Justus, Timothy; Bigand, Emmanuel

    2007-01-01

    Recent findings suggest the involvement of the cerebellum in perceptual and cognitive tasks. Our study investigated whether cerebellar patients show musical priming based on implicit knowledge of tonal-harmonic music. Participants performed speeded phoneme identification on sung target chords, which were either related or less-related to prime contexts in terms of the tonal-harmonic system. As groups, both cerebellar patients and age-matched controls showed facilitated processing for related ...

  15. Photophysical Properties of Aromatic and Antiaromatic Porphyrinoids

    Science.gov (United States)

    2011-04-14

    Chem. B, 2007, 111, 2138. 18 List of Publications 1. Large Porphyrin Squares from the Self-Assembly of meso- Triazole -Appended L-Shaped meso–meso...Linked ZnII–Triporphyrins: Synthesis and Efficient Energy Transfer  Chihiro Maeda, Pyosang Kim, Sung Cho, Jong Kang Park, Jong Min Lim, Dongho Kim...Characterization of Tri(Cyclopentaphenanthrene)-Derived Nanoparticles: A Template Free Synthesis of Hollow Colloidosomes.  Shanmugam Easwaramoorthi, Pyosang

  16. Sandarbh UK International Artist Residency Program Belper Derbyshire

    OpenAIRE

    White, Laura

    2009-01-01

    Sandarbh Artist Residency. Laura White participated in this residency. 2009. She was one of 13 international artists working in location together over 2 weeks. Each artist developed a separate project. Participating artists included: Ivan Smith UK, Laura White UK, Francis Gomila UK/GER, Lata Upadhyaya UK/IND, Istvan Eross HUN, Chintan Upadhyay IND, Liu Po-Chun TW, Tsai Kung-Lin TW, Dong-Hun Sung KR, Alvaro Verduzcos MEX, Abby Manock US, Anke Mellin, GER. Concept of Resi...

  17. Review: Benjamin Crabtree & William Miller (Eds.) (1999). Doing Qualitative Research (2nd edition)

    OpenAIRE

    2002-01-01

    Das Buch ist ein Muss für alle qualitativ Forschenden im Themenfeld Gesundheit. Den Lesenden wird ein Überblick zu qualitativen Methoden geboten und unterschiedliche Erhebungsverfahren und Auswertungsstrategien werden zusammen mit einigen besonderen Forschungsdesigns vorgestellt. Besonders wertvoll sind die detaillierten Beispiele tatsächlicher Forschungsprobleme und die angebotenen Vorschläge zu deren Lösung. In Anbetracht der Komplexität der Verfahren und Forschungsdesigns, die vorgestellt ...

  18. Real-time magnetic resonance imaging investigation of resonance tuning in soprano singing

    OpenAIRE

    Bresch, Erik; Narayanan, Shrikanth

    2010-01-01

    This article investigates using real-time magnetic resonance imaging the vocal tract shaping of 5 soprano singers during the production of two-octave scales of sung vowels. A systematic shift of the first vocal tract resonance frequency with respect to the fundamental is shown to exist for high vowels across all subjects. No consistent systematic effect on the vocal tract resonance could be shown across all of the subjects for other vowels or for the second vocal tract resonance.

  19. 动态信息(英文)

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    ‘Snakehead’Sentenced to Death大陆私渡女被溺毙案“蛇头”被判死刑Wang Chung-hsing, the prime suspect in the drowning deaths of six Chinese mainland women, who were being smuggled across the Taiwan Straits, was sentenced to death last November by Taiwan's Miaoli District Court. Co-accused Ko Ching-sung was sentenced to life in prison. The defendants were

  20. Anisotrope Schädigungsmodellierung von Beton mit Adaptiver Bruchenergetischer Regularisierung

    OpenAIRE

    2008-01-01

    Der Gegenstand der vorliegenden Arbeit ist die Simulation von Betonstrukturen beliebiger Geometrie unter überwiegender Zugbelastung. Die Modellierung erfolgt auf Makroebene als Kontinuum und zur Lösung des mechanischen Feldproblems wird die Finite-Elemente-Methode verwendet. Ein neues Materialmodell für Beton und eine Erweiterung der Bruchenergetischen Regularisierung werden vorgestellt. Die Arbeit ist in zwei Teile gegliedert. Im ersten Teil wird ein lokales, anisotropes Schädigungsmodell ab...

  1. "She ain't no human being": le rock anglais chante sa reine

    OpenAIRE

    Chastagner, Claude

    1995-01-01

    The Beatles, The Smiths and The Sex Pistols have all sung the Queen, to celebrate or denigrate her. But in all cases, it is the sacrificial victim more than the human being or the official figure that is put forward.; The Beatles, The Smiths et The Sex Pistols ont tous les trois chanté la reine, une reine vilipendée ou célébrée mais toujours posée comme une victime sacrificielle.

  2. Cognition in the Brain: Investigations Using Positron Emission Tomography

    Science.gov (United States)

    1992-07-16

    0029 DDIRESS (City. State and ZIP Code) 10. SOURCE Of FUNDING NOS. _____________ .dg. 410 PROGRAM PROJECT TASKC WORK .,%r illing Air Force Base, DC...Bethesda, MD 20892 20. Daniel Bubb, M.D. Department of Neurolinguistics Montreal Neurological Institute 15. Sung-cheng tHuang, Ph.D. 3801 University...Chief of Pediatric Neu- rology Service Director, Center for Morphomet- 24. Terry Allard, Ph.D. ric Analysis Cognitive Science Programs Kennedy 9 Office

  3. Música popular y nacionalismo en los campamentos insurgentes. Cuba (1895-1898) /Popular Music and Nationalism in Insurgent Camps. Cuba (1895-1898)/Música popular e nacionalismo nos acampamentos insurgentes. Cuba (1895-1898)

    National Research Council Canada - National Science Library

    Jaddiel Díaz Frene

    2015-01-01

    ...? Palabras clave: música, Cuba, nacionalismo, cultura popular, raza, género, décimas. Popular Music and Nationalism in Insurgent Camps. Cuba (1895-1898) Abstract: This article reconstructs the social uses of the décimas (ten-line stanzas) sung in the insurgent camps during the war for independence that began in Cuba in 1895. Through a review of persona...

  4. Machine Learning for Education: Learning to Teach

    Science.gov (United States)

    2016-12-01

    1 Machine Learning for Education: Learning to Teach Matthew C. Gombolay, Reed Jensen, Sung-Hyun Son Massachusetts Institute of Technology Lincoln...training tools and develop military strategies within their training environment. Second, we develop methods for improving warfighter education: learning to...and do not necessarily reflect the views of the Department of the Navy. RAMS # 1001485 Fig. 1. SGD enables development of automated teaching tools for

  5. Resenhas v. 3 n. 6

    Directory of Open Access Journals (Sweden)

    Aurino José Góis

    2009-05-01

    Full Text Available BERGER, P. L.; LUCKMANN, T.Modernidade, pluralismo e crise de sentido; a orientação do homem modernoAurino José GóisRIBEIRO, Renato Janine. A república.RIBEIRO, Renato Janine. A democracia.João Carlos Lino GomesSUNG, Jung Mo. Sementes de esperança. A fé em um mundo em crise.Flávio Senra

  6. A LAMENT OF CYPRUS REGION: “ARAB ALİ” AND VARIATIONS

    OpenAIRE

    Şevket ÖZNUR

    2011-01-01

    This article is about the research of the lament text lamented for Arap Ali who was killed in 1943 in Famagusta, Cyprus by English soldiers. This lament was sung among people so many times that we encounter (can see) its different variations in Kerkük and Anatolia. As a matter of fact the story, the contrastive analyis and similarity and difference of these variants have been evaluated. Besides interpretation, research and evaluation inthe frame of literature and language evaluation, local fo...

  7. Wenn Philosophen aus der Hüfte schießen

    Directory of Open Access Journals (Sweden)

    Schramme Thomas

    2015-12-01

    Full Text Available In diesem Artikel wird argumentiert, dass die Philosophie nicht über passende Methoden verfügt, reale politische Probleme angemessen zu analysieren. So sind die tatsächlich vorzufindenden Empfehlungen zur Lösung solcher Fragen meist trivial oder unterkomplex. Es wird geraten, zuerst geeignete Instrumentarien der angewandten bzw. konkreten Ethik zu entwickeln, bevor sich PhilosophInnen zu solch komplexen Fragen wie die der Flüchtlingspolitik äußern.

  8. Biothermodynamische Studien zur Adsorption monoklonaler Antikörper an chromatographischen Trennmaterialien

    OpenAIRE

    Dieterle, Michael

    2009-01-01

    Monoklonale Antikörper sind therapeutische Proteine mit großem Potential in der modernen Medizin. Für ihre kostenoptimierte Produktion und ein rationales Design der technischen Trennprozesse ist ein Verständnis der Zusammenhänge zwischen den Prozessparametern, den Vorgängen in der Proteinlösung und dem Adsorptionsvorgang notwendig. In der vorliegenden Arbeit wurden systematisch thermodynamische Untersuchungen zum Adsorptionsvorgang zweier monoklonaler Antikörper an CEC-Trennmaterialien sowie ...

  9. Probability-Based Inference in Cognitive Diagnosis

    Science.gov (United States)

    1994-02-01

    with Anne B6land, Drew Gitomer, Irvin Katz, Sung-Ho Kim, Paul Nichols, Kikumi Tatsuoka, and Tony Thompson. Abstract Recent developments in cognitive...50, 157-224. Lazarsfeld , P.F. (1950). The logical and mathematical foundation of latent structure analysis. In S.A. Stouffer, L. Guttman, E.A...Suchman, P.F. Lazarsfeld , S.A. Star, & J.A. Clausen, Studies in social psychology in World War!!, Volume 4: Measurement and prediction (pp. 362-412

  10. Understanding the North Korea Problem: Why It Has Become the "Land of Lousy Options"

    Science.gov (United States)

    2011-07-01

    Kim Il Sung, who arguably continues to be the ruling figure—the “ Eternal President”—in North Korea even after his death. Kim Il Sungism may have...Jung’s “ Sunshine Policy.” This policy marked a radical shift in South Korean strategy toward the North. It effectively separated eco- nomic issues...inter-Korean reconciliation, was an effort to overhaul the “ Sunshine Policy.” However, it also failed because of the deepening domestic political

  11. Terahertz biomedical science and technology

    CERN Document Server

    Son, Joo-Hiuk

    2014-01-01

    Introduction to Biomedical Studies Using Terahertz WavesJoo-Hiuk SonSection I Terahertz TechnologyTerahertz Sources and DetectorsHyunyong Choi and Joo-Hiuk SonTabletop High-Power Terahertz Pulse Generation TechniquesYun-Shik LeeTerahertz Imaging and Tomography TechniquesHyunyong Choi and Joo-Hiuk SonCompact Solid-State Electronic Terahertz Devices and CircuitsJae-Sung Rieh, Daekeun Yoon, and Jongwon Yun<

  12. Jede Frage, die ein Gutachter, Berater oder Therapeut stellt, ist schon eine Intervention! Lösungsorientierung o d e r Problemorientierung? Kompetenzorientierung o d e r Defizitorientierung?

    OpenAIRE

    Himmelreich, Arndt

    2001-01-01

    Vortrag von Arndt Himmelreich. Thema: Lösungsorientierung bzw. Problemorientierung in der Verkehrstherapie. Ambivalenz-Coaching: hypno-systemische Methoden zur Erhöhung der Rollen- und Kontextflexibilität durch Offenlegung innerer Konflikte (konstruktive, sinnlich faßbare Externalisierung der "mich innerlich auffressenden Monster") nach Milton H. Erickson und Gunther Schmidt; Balance von lösungsorientierter ("Ab-Lösung von dem hypnotisch starren Blick auf das Problem") mit eben auch der p...

  13. Lösungsorientierung o d e r Problemorientierung? Kompetenzorientierung o d e r Defizitorientierung? Jede Frage, die ein Gutachter, Berater oder Therapeut stellt, ist schon eine Intervention!

    OpenAIRE

    Himmelreich, Arndt

    2001-01-01

    Vortrag von Arndt Himmelreich. Thema: Lösungsorientierung bzw. Problemorientierung in der Verkehrstherapie. Ambivalenz-Coaching: hypno-systemische Methoden zur Erhöhung der Rollen- und Kontextflexibilität durch Offenlegung innerer Konflikte (konstruktive, sinnlich faßbare Externalisierung der "mich innerlich auffressenden Monster") nach Milton H. Erickson und Gunther Schmidt; Balance von lösungsorientierter ("Ab-Lösung von dem hypnotisch starren Blick auf das Problem") mit eben auch der p...

  14. Entwicklung und Evaluation einer Methode zur Erhöhung der Arzneimitteltherapiesicherheit in der Psychiatrie

    OpenAIRE

    2016-01-01

    Zahlreiche Risikofaktoren psychoparmakotherapeutsichen Behandlung bedingen das häufige Auftreten von Medikationsfehlern und Nebenwirkungen. Medikationsfehler und Nebenwirkungen werden unter dem Begriff Arzneimittelbezogene Probleme (ABP) zusammengefasst. Für das psychiatrische Setting gibt es bisher nur wenige Studien, die sich mit der Prävalenz von ABP sowie der Evaluierung effektiver Maßnahmen zur Lösung und Prävention identifizierter ABP auseinandersetzten. In anderen medizinischen Diszipl...

  15. The I pouch ileal neobladder: Oncological and functional outcomes

    OpenAIRE

    Abdelhafez, Mohamed

    2014-01-01

    Verschiedene onkologische und patientenbezogene Faktoren können Einfluss nehmen auf die Wahl der Harnableitung nach radikaler Zystektomie bei invasiven Harnblasenkarzinom. Die orthotope Neoblase unter Verwendung von terminalem Ileum stellt die am häufigsten vorgenommene Harnableitungsform in nationalen und internationalen klinischen Zentren dar. Es gibt zahlreiche technische Variationen einer ilealen Neoblase, die in einem Versuch, eine perfekte Lösung für eine orthotopen Harnableitung zu err...

  16. Symplectic tracking and compensation of dynamic field integrals in complex undulator structures

    Directory of Open Access Journals (Sweden)

    Johannes Bahrdt

    2011-04-01

    Full Text Available In first approximation storage ring multipole magnets are described as simple two-dimensional magnet structures and many linear and nonlinear beam optic features of a magnet lattice can already be derived from this model. In contrast, undulators, and in particular variably polarizing devices, employ complicated three-dimensional magnetic fields which may have a severe impact on the electron beam, in particular, in low energy third generation storage rings. A Taylor expanded generating function method is presented to generate a fast, flexible, and symplectic mapping routine for particle tracking in magnetic fields. This method is quite general and is based on the solution of the Hamilton-Jacobi equation. It requires an analytical representation of the fields, which can be differentiated and integrated. For undulators of the APPLE II type, an accurate analytic field model is derived which is suitable for the tracking routine. This field model is fully parametrized representing all operation modes for the production of elliptical or linear polarized light with an arbitrary inclination angle or even arbitrary polarization. Based on this field model, analytic expressions for 2nd order kicks are derived. They are used to estimate the influence of APPLE II undulators on the electron beam dynamic. Furthermore, an analytic model for the description of shims is given. The shims are needed for field and performance optimization. Passive and active shimming concepts for the compensation of linear and nonlinear effects of variably polarizing undulators are discussed.

  17. Development of High-Field Permanent Magnetic Circuits for NMRI/MRI and Imaging on Mice

    Directory of Open Access Journals (Sweden)

    Guangxin Wang

    2016-01-01

    Full Text Available The high-field permanent magnetic circuits of 1.2 T and 1.5 T with novel magnetic focusing and curved-surface correction are developed. The permanent magnetic circuit comprises a magnetic yoke, main magnetic steel, nonspherical curved-surface magnetic poles, plugging magnetic steel, and side magnetic steel. In this work, a novel shimming method is proposed for the effective correction of base magnetic field (B0 inhomogeneities, which is based on passive shimming on the telescope aspheric cutting, grinding, and fine processing technology of the nonspherical curved-surface magnetic poles and active shimming adding higher-order gradient coils. Meanwhile, the magnetic resonance imaging dedicated alloy with high-saturation magnetic field induction intensity and high electrical resistivity is developed, and nonspherical curved-surface magnetic poles which are made of the dedicated alloy have very good anti-eddy-current effect. In addition, the large temperature coefficient problem of permanent magnet can be effectively controlled by using a high quality temperature controller and deuterium external locking technique. Combining our patents such as gradient coil, RF coil, and integration computer software, two kinds of small animal Micro-MRI instruments are developed, by which the high quality MRI images of mice were obtained.

  18. Resolution Improvements in in Vivo1H NMR Spectra with Increased Magnetic Field Strength

    Science.gov (United States)

    Gruetter, Rolf; Weisdorf, Sally A.; Rajanayagan, Vasantham; Terpstra, Melissa; Merkle, Hellmut; Truwit, Charles L.; Garwood, Michael; Nyberg, Scott L.; Ugurbil, Kâmil

    1998-11-01

    The measurement of cerebral metabolites using highly homologous localization techniques and similar shimming methods was performed in the human brain at 1.5 and 4 T as well as in the dog and rat brain at 9.4 T. In rat brain, improved resolution was achieved by shimming all first- and second-order shim coils using a fully adiabatic FASTMAP sequence. The spectra showed a clear improvement in spectral resolution for all metabolite resonances with increased field strength. Changes in cerebral glutamine content were clearly observed at 4 T compared to 1.5 T in patients with hepatic encephalopathy. At 9.4 T, glutamine H4 at 2.46 ppm was fully resolved from glutamate H4 at 2.37 ppm, as was the potential resonance from γ-amino-butyric acid at 2.30 ppm and N-acetyl-aspartyl-glutamate at 2.05 ppm. Singlet linewidths were found to be as low as 6 Hz (0.015 ppm) at 9.4 T, indicating a substantial decrease in ppm linewidth with field strength. Furthermore, the methylene peak of creatine was partially resolved from phosphocreatine, indicating a close to 1:1 relationship in gray matter. We conclude that increasing the magnetic field strength increases spectral resolution also for1H NMR, which can lead to more than linear sensitivity gains.

  19. Investigation of reactivity variations of the Isfahan MNSR reactor due to variations in the thickness of the core top beryllium layer using WIMSD and MCNP codes

    Directory of Open Access Journals (Sweden)

    A Shirani

    2010-12-01

    Full Text Available In this work, the Isfahan Miniature Neutron Source Reactor (MNSR is first simulated using the WIMSD code, and its fuel burn-up after 7 years of operation ( when the reactor was revived by adding a 1.5 mm thick beryllium shim plate to the top of its core and also after 14 years of operation (total operation time of the reactor is calculated. The reactor is then simulated using the MCNP code, and its reactivity variation due to adding a 1.5 mm thick beryllium shim plate to the top of the reactor core, after 7 years of operation, is calculated. The results show good agreement with the available data collected at the revival time. Exess reactivity of the reactor at present time (after 14 years of operation and after 7 years of the the reactor revival time is also determined both experimentally and by calculation, which show good agreement, and indicate that at the present time there is no need to add any further beryllium shim plate to the top of the reactor core. Furthermore, by adding more beryllium layers with various thicknesses to the top of the reactor core, in the input program of the MCNP program, reactivity value of these layers is calculated. From these results, one can predict the necessary beryllium thickness needed to reach a desired reactivity in the MNSR reactor.

  20. Speech versus singing: Infants choose happier sounds

    Directory of Open Access Journals (Sweden)

    Marieve eCorbeil

    2013-06-01

    Full Text Available Infants prefer speech to non-vocal sounds and to non-human vocalizations, and they prefer happy-sounding speech to neutral speech. They also exhibit an interest in singing, but there is little knowledge of their relative interest in speech and singing. The present study explored infants’ attention to unfamiliar audio samples of speech and singing. In Experiment 1, infants 4-13 months of age were exposed to happy-sounding infant-directed speech versus hummed lullabies by the same woman. They listened significantly longer to the speech, which had considerably greater acoustic variability and expressiveness, than to the lullabies. In Experiment 2, infants of comparable age who heard the lyrics of a Turkish children’s song spoken versus sung in a joyful/happy manner did not exhibit differential listening. Infants in Experiment 3 heard the happily sung lyrics of the Turkish children’s song versus a version that was spoken in an adult-directed or affectively neutral manner. They listened significantly longer to the sung version. Overall, happy voice quality rather than vocal mode (speech or singing was the principal contributor to infant attention, regardless of age.

  1. Music enhances verbal episodic memory in Alzheimer's disease.

    Science.gov (United States)

    Palisson, Juliette; Roussel-Baclet, Caroline; Maillet, Didier; Belin, Catherine; Ankri, Joël; Narme, Pauline

    2015-01-01

    Although previous studies suggest that music may facilitate verbal learning in a healthy population, such a mnemonic effect has seldom been investigated in Alzheimer's disease (AD). Moreover, memorization of texts was generally compared when either sung or spoken. In the present study, it was examined whether the benefit observed on verbal learning was specific to music or whether an associative context binding items together led to similar benefits, regardless of the nature of the association. Twelve patients with mild AD and 15 healthy controls learned texts presented with either a musical (sung) or a nonmusical association (spoken associated to a silent movie sequence) or without association (spoken alone). Immediate and delayed (after a 5-min delay) recall was measured. Main results showed that (a) sung texts were better remembered than spoken texts, both immediately and after a retention delay, for both groups; (b) the musical benefit was robust, being observed in most AD patients; (c) the nonmusical association may also facilitate verbal learning but to a lesser extent. A musical association during the encoding stage facilitates learning and retention in AD. Furthermore, this advantage seemed quite specific to music. The results are discussed with respect to the clinical applications in AD; theoretical implications are highlighted to explain the power of music as a mnemonic technique.

  2. Speech vs. singing: infants choose happier sounds

    Science.gov (United States)

    Corbeil, Marieve; Trehub, Sandra E.; Peretz, Isabelle

    2013-01-01

    Infants prefer speech to non-vocal sounds and to non-human vocalizations, and they prefer happy-sounding speech to neutral speech. They also exhibit an interest in singing, but there is little knowledge of their relative interest in speech and singing. The present study explored infants' attention to unfamiliar audio samples of speech and singing. In Experiment 1, infants 4–13 months of age were exposed to happy-sounding infant-directed speech vs. hummed lullabies by the same woman. They listened significantly longer to the speech, which had considerably greater acoustic variability and expressiveness, than to the lullabies. In Experiment 2, infants of comparable age who heard the lyrics of a Turkish children's song spoken vs. sung in a joyful/happy manner did not exhibit differential listening. Infants in Experiment 3 heard the happily sung lyrics of the Turkish children's song vs. a version that was spoken in an adult-directed or affectively neutral manner. They listened significantly longer to the sung version. Overall, happy voice quality rather than vocal mode (speech or singing) was the principal contributor to infant attention, regardless of age. PMID:23805119

  3. Dynamic scattering of electron vortex beams – A Bloch wave analysis

    Energy Technology Data Exchange (ETDEWEB)

    Mendis, B.G., E-mail: b.g.mendis@durham.ac.uk

    2015-02-15

    Two important applications of electron vortex beams are in electron magnetic chiral dichroism (EMCD) measurements and nanoparticle manipulation. In both cases orbital angular momentum () transfer between the vortex beam and the specimen due to dynamic scattering is critical. In general the pendellösung consists of short and long wavelength oscillations. The former is due to interference between the tightly bound 1s and more dispersive non-1s Bloch states, while the latter is due to interference between the non-1s states. For EMCD experiments with ±ħ angular momentum beams, momentum transfer can be minimised by selecting the appropriate aperture size, so that the probe wavefunction approximately matches that of the 2p-type Bloch states. For manipulating nanoparticles with large angular momentum beams small apertures are required to excite the 1s state and thereby enhance the short wavelength oscillations in . This enables efficient momentum transfer to the specimen, provided the nanoparticle dimension corresponds to a minimum in the pendellösung. - Highlights: • Dynamic scattering of vortex beams is analysed using Bloch waves. • Fundamental origins of pendellösung oscillations are identified. • Effect on magnetic dichroism measurements and nanoparticle manipulation is discussed.

  4. On the electron vortex beam wavefunction within a crystal

    Energy Technology Data Exchange (ETDEWEB)

    Mendis, B.G., E-mail: b.g.mendis@durham.ac.uk

    2015-10-15

    Electron vortex beams are distorted by scattering within a crystal, so that the wavefunction can effectively be decomposed into many vortex components. Using a Bloch wave approach equations are derived for vortex beam decomposition at any given depth and with respect to any frame of reference. In the kinematic limit (small specimen thickness) scattering largely takes place at the neighbouring atom columns with a local phase change of π/2 rad. When viewed along the beam propagation direction only one vortex component is present at the specimen entrance surface (i.e. the ‘free space’ vortex in vacuum), but at larger depths the probe is in a mixed state due to Bragg scattering. Simulations show that there is no direct correlation between vortex components and the pendellösung, i.e. at a given depth probes with relatively constant can be in a more mixed state compared to those with more rapidly varying . This suggests that minimising oscillations in the pendellösung by probe channelling is not the only criterion for generating a strong electron energy loss magnetic circular dichroism (EMCD) signal. - Highlights: • Equations are derived for vortex decomposition due to scattering within a crystal. • There is no direct correlation between vortex decomposition and pendellösung. • Results are also discussed in the context of EMCD measurements.

  5. Effect of musical experience on verbal memory in Williams syndrome: evidence from a novel word learning task.

    Science.gov (United States)

    Martens, Marilee A; Jungers, Melissa K; Steele, Anita L

    2011-09-01

    Williams syndrome (WS) is a neurogenetic developmental disorder characterized by an increased affinity for music, deficits in verbal memory, and atypical brain development. Music has been shown to improve verbal memory in typical individuals as well as those with learning difficulties, but no studies have examined this relationship in WS. The aim of our two studies was to examine whether music can enhance verbal memory in individuals with WS. In Study 1, we presented a memory task of eight spoken or sung sentences that described an animal and identified its group name to 38 individuals with WS. Study 2, involving another group of individuals with WS (n=38), included six spoken or sung sentences that identified an animal group name. In both studies, those who had participated in formal music lessons scored significantly better on the verbal memory task when the sentences were sung than when they were spoken. Those who had not taken formal lessons showed no such benefit. We also found that increased enjoyment of music and heightened emotional reactions to music did not impact performance on the memory task. These compelling findings provide the first evidence that musical experience may enhance verbal memory in individuals with WS and shed more light on the complex relationship between aspects of cognition and altered neurodevelopment in this unique disorder. Copyright © 2011 Elsevier Ltd. All rights reserved.

  6. Dextran-b-poly(L-histidine copolymer nanoparticles for pH-responsive drug delivery to tumor cells

    Directory of Open Access Journals (Sweden)

    Hwang JH

    2013-08-01

    Full Text Available Jong-Ho Hwang,1,2 Cheol Woong Choi,1 Hyung-Wook Kim,1 Do Hyung Kim,3 Tae Won Kwak,3 Hye Myeong Lee,3 Cy Hyun Kim,3 Chung Wook Chung,3 Young-Il Jeong,3 Dae Hwan Kang1,3 1Department of Internal Medicine, Medical Research Institute, Pusan National University School of Medicine, Yangsan, Republic of Korea; 2Department of Internal Medicine, Busan Medical Center, Yeonje-gu, Busan, Republic of Korea; 3National Research and Development Center for Hepatobiliary Disease, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea Purpose: Nanoparticles based on stimuli-sensitive drug delivery have been extensively investigated for tumor targeting. Among them, pH-responsive drug targeting using pH-sensitive polymers has attracted attention because solid tumors have an acidic environment. A dextran-b-poly(L-histidine (DexPHS copolymer was synthesized and pH-responsive nanoparticles were fabricated for drug targeting. Methods and results: A DexPHS block copolymer was synthesized by attaching the reductive end of dextran to the amine groups of poly(L-histidine. pH-responsive nanoparticles incorporating doxorubicin were fabricated and studied in HuCC-T1 cholangiocarcinoma cells. Synthesis of DexPHS was confirmed by 1H nuclear magnetic resonance spectroscopy, with specific peaks of dextran and PHS observed at 2–5 ppm and 7.4–9.0 ppm, respectively. DexPHS nanoparticles showed changes in particle size with pH sensitivity, ie, the size of the nanoparticles increased at an acidic pH and decreased at a basic pH. DexPHS block copolymer nanoparticles incorporating doxorubicin were prepared using the nanoprecipitation dialysis method. The doxorubicin release rate was increased at acidic pH compared with basic pH, indicating that DexPHS nanoparticles have pH-sensitive properties and that drug release can be controlled by variations in pH. The antitumor activity of DexPHS nanoparticles incorporating doxorubicin were studied using HuCC-T1

  7. Performance Evaluation and Analysis of Critical Interface Features of the National Compact Stellarator Experiment (NCSX)

    Energy Technology Data Exchange (ETDEWEB)

    Freudenberg, Kevin D [ORNL; Litherland, P Steve [ORNL; Cole, Michael J [ORNL; Williamson, David E [ORNL; Goranson, Paul L [ORNL; Nelson, Brad E [ORNL; Heitzenroeder, P. [Princeton Plasma Physics Laboratory (PPPL); Myatt, R. [Myatt Consulting, Norfolk, MA

    2009-01-01

    The (18) modular coils for the National Compact Stellarator Experiment (NCSX) are joined at assembly by interfaces to form a toroidal shell which serves as the structural backbone of the device. There are six each of three coil types (A, B, and C); consequently, there are 4 distinct interface designs (A-A, A-B, B-C, C-C). This paper describes the performance evaluations and analyses used in the development of these critical interfaces. Initial analyses indicated that the baseline interface designs did not provide adequate shear capability along the inner (unbolted) legs between the modular coils and did not adequately address assembly tolerance requirements. Consequently a design effort was undertaken to develop interfaces with adequate shear capability and which would facilitate the achievement of assembly tolerances. Analyses indicated that a friction coefficient of 0.3 is necessary for 'no-slip' joints with a preload value of {approx}320 kN in the outboard regions. Two types of compatible segmented friction shims were developed to meet the friction requirement. One type uses alumina coated stainless steel shims and the other uses G-10/ stainless steel/ G-10 'sandwich shims.' Analyses indicated that the time constant requirements for induced currents in the shell could still be achieved with welds along all the inner (unbolted) legs except at the C-C interface. Consequently, welded interfaces utilizing alternating MIG fillet welds on each end of shims between coil castings were developed to react the shear loads. This configuration minimizes distortion since it avoids direct weld shrinkage stress across the interfaces. Analyses indicates that a 12.7 mm fillet weld has adequate shear capability, with average stress through the welds of 90-125 MPa, compared to a static limit of 217 MPa. Custom sized compression pucks located in the middle of the welded shims react the compressive loads and have average stresses less than 137 MPa. Fatigue

  8. Pericyte-targeting drug delivery and tissue engineering

    Directory of Open Access Journals (Sweden)

    Kang E

    2016-05-01

    Full Text Available Eunah Kang,1 Jong Wook Shin2 1School of Chemical Engineering and Material Science, 2Division of Allergic and Pulmonary Medicine, Department of Internal Medicine, College of Medicine, Chung-Ang University, Dongjak-Gu, Seoul, South Korea Abstract: Pericytes are contractile mural cells that wrap around the endothelial cells of capillaries and venules. Depending on the triggers by cellular signals, pericytes have specific functionality in tumor microenvironments, properties of potent stem cells, and plasticity in cellular pathology. These features of pericytes can be activated for the promotion or reduction of angiogenesis. Frontier studies have exploited pericyte-targeting drug delivery, using pericyte-specific peptides, small molecules, and DNA in tumor therapy. Moreover, the communication between pericytes and endothelial cells has been applied to the induction of vessel neoformation in tissue engineering. Pericytes may prove to be a novel target for tumor therapy and tissue engineering. The present paper specifically reviews pericyte-specific drug delivery and tissue engineering, allowing insight into the emerging research targeting pericytes. Keywords: pericytes, pericyte-targeting drug delivery, tissue engineering, platelet-derived growth factor, angiogenesis, vascular remodeling

  9. Clinical experiences in fungal keratitis caused by Acremonium

    Directory of Open Access Journals (Sweden)

    Kim SJ

    2014-01-01

    Full Text Available Seong-Jae Kim,1,2 Yong-Wun Cho,1 Seong-Wook Seo,1,2 Sun-Joo Kim,2,3 Ji-Myong Yoo1,21Department of Ophthalmology, 2Gyeongsang Institute of Health Science, 3Department of Laboratory Medicine, Gyeongsang National University, College of Medicine, Jinju, KoreaPurpose: To report the predisposing risk factors, clinical presentation, management, and therapeutic outcomes of fungal keratitis caused by Acremonium.Methods: This is a retrospective study of cases with Acremonium fungal keratitis that presented to our tertiary referral center between January 2006 and August 2012. Patient demographic and clinical details were determined and reported.Results: Five cases of fungal keratitis from Acremonium species were identified in five patients (three males, two females. The mean age of the patients was of 73.4±5.46 years, with a mean follow-up time of 124±72 days. All patients had a history of corneal trauma with vegetable matter. Four cases were unresponsive to initial treatment (0.2% fluconazole, 0.15% amphotericin B and required topical 5% natamycin, and, in two out of five cases, topical 1% voriconazole.Conclusion: The most common risk factors for Acremonium fungal keratitis was ocular trauma. When a corneal lesion is found to be unresponsive to the initial treatment, we should consider adding or substituting topical natamycin or voriconazole for treatment.Keywords: Acremonium, fungal keratitis, natamycin, prognosis, voriconazole

  10. Biomimetics: forecasting the future of science, engineering, and medicine

    Directory of Open Access Journals (Sweden)

    Hwang J

    2015-09-01

    Full Text Available Jangsun Hwang,1 Yoon Jeong,1,2 Jeong Min Park,3 Kwan Hong Lee,1,2,4 Jong Wook Hong,1,2 Jonghoon Choi1,2 1Department of Bionano Technology, Graduate School, Hanyang University, Seoul, 2Department of Bionano Engineering, Hanyang University ERICA, Ansan, Korea; 3Department of Biomedical Engineering, Boston University, 4OpenView Venture Partners, Boston, MA, USA Abstract: Biomimetics is the study of nature and natural phenomena to understand the principles of underlying mechanisms, to obtain ideas from nature, and to apply concepts that may benefit science, engineering, and medicine. Examples of biomimetic studies include fluid-drag reduction swimsuits inspired by the structure of shark’s skin, velcro fasteners modeled on burrs, shape of airplanes developed from the look of birds, and stable building structures copied from the backbone of turban shells. In this article, we focus on the current research topics in biomimetics and discuss the potential of biomimetics in science, engineering, and medicine. Our report proposes to become a blueprint for accomplishments that can stem from biomimetics in the next 5 years as well as providing insight into their unseen limitations. Keywords: biomimicry, tissue engineering, biomaterials, nature, nanotechnology, nanomedicine

  11. Nanoscale bacteriophage biosensors beyond phage display

    Directory of Open Access Journals (Sweden)

    Lee JW

    2013-10-01

    Full Text Available Jong-Wook Lee,1 Jangwon Song,1,2 Mintai P Hwang,1 Kwan Hyi Lee1,2 1Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Korea; 2Department of Biomedical Engineering, University of Science and Technology, Seoul, Korea Abstract: Bacteriophages are traditionally used for the development of phage display technology. Recently, their nanosized dimensions and ease with which genetic modifications can be made to their structure and function have put them in the spotlight towards their use in a variety of biosensors. In particular, the expression of any protein or peptide on the extraluminal surface of bacteriophages is possible by genetically engineering the genome. In addition, the relatively short replication time of bacteriophages offers researchers the ability to generate mass quantities of any given bacteriophage-based biosensor. Coupled with the emergence of various biomarkers in the clinic as a means to determine pathophysiological states, the development of current and novel technologies for their detection and quantification is imperative. In this review, we categorize bacteriophages by their morphology into M13-based filamentous bacteriophages and T4- or T7-based icosahedral bacteriophages, and examine how such advantages are utilized across a variety of biosensors. In essence, we take a comprehensive approach towards recent trends in bacteriophage-based biosensor applications and discuss their outlook with regards to the field of biotechnology. Keywords: biosensing, M13 bacteriophage, T4 bacteriophage, bacterial detection, Escherichia coli, SPR sensor

  12. Enhanced therapeutic efficacy of budesonide in experimental colitis with enzyme/pH dual-sensitive polymeric nanoparticles

    Directory of Open Access Journals (Sweden)

    Naeem M

    2015-07-01

    Full Text Available Muhammad Naeem, Jiafu Cao, Moonjeong Choi, Woo Seong Kim, Hyung Ryong Moon, Bok Luel Lee, Min-Soo Kim, Yunjin Jung, Jin-Wook Yoo College of Pharmacy, Pusan National University, Busan, South Korea Abstract: Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitive nanoparticles using enzyme-sensitive azo-polyurethane and pH-sensitive methacrylate copolymer for the treatment of colitis. The therapeutic potential of the enzyme/pH dual-sensitive nanoparticles was evaluated using a rat colitis model and compared to single pH-triggered nanoparticles. Clinical activity scores, colon/body weight ratios, myeloperoxidase activity, and proinflammatory cytokine levels were markedly decreased by dual-sensitive nanoparticles compared to single pH-triggered nanoparticles and budesonide solution. Moreover, dual-sensitive nanoparticles accumulated selectively in inflamed segments of the colon. In addition, dual-sensitive nanoparticle plasma concentrations were lower than single pH-triggered nanoparticles, and no noticeable in vitro or in vivo toxicity was observed. Our results demonstrate that enzyme/pH dual-sensitive nanoparticles are an effective and safe colon-targeted delivery system for colitis therapy. Keywords: azo-polyurethane, methacrylate copolymer, budesonide, colon-targeted nanoparticles, colitis

  13. A glimpse into the interactions of cells in a microenvironment: the modulation of T cells by mesenchymal stem cells

    Directory of Open Access Journals (Sweden)

    Choi J

    2014-05-01

    Full Text Available Jonghoon Choi,1,2 Mintai P Hwang,3 Jong-Wook Lee,3 Kwan Hyi Lee3,41Institute of Research Strategy and Development (IRSD, Seoul, Republic of Korea; 2Department of Bionano Engineering, Hanyang University, Ansan, Republic of Korea; 3Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea; 4Department of Biomedical Engineering, University of Science and Technology, Seoul, Republic of KoreaAbstract: Mesenchymal stem cells (MSCs have been thought to hold potential as a mode of therapy for immuno-related pathologies, particularly for autoimmune diseases. Despite their potential, the interaction between MSCs and T cells, key players in the pathophysiology of autoimmune diseases, is not yet well understood, thereby preventing further clinical progress. A major obstacle is the highly heterogeneous nature of MSCs in vitro. Unfortunately, bulk assays do not provide information with regard to cell–cell contributions that may play a critical role in the overall cellular response. To address these issues, we investigated the interaction between smaller subsets of MSCs and CD4 T cells in a microwell array. We demonstrate that MSCs appear capable of modulating the T cell proliferation rate in response to persistent cell–cell interactions, and we anticipate the use of our microwell array in the classification of subpopulations within MSCs, ultimately leading to specific therapeutic interventions.Keywords: mesenchymal stem cell, T cell, microwell array

  14. Improving dissolution and oral bioavailability of pranlukast hemihydrate by particle surface modification with surfactants and homogenization

    Directory of Open Access Journals (Sweden)

    Ha ES

    2015-06-01

    Full Text Available Eun-Sol Ha,1 In-hwan Baek,2 Jin-Wook Yoo,1 Yunjin Jung,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2College of Pharmacy, Kyungsung University, Busan, Republic of Korea Abstract: The present study was carried out to develop an oral formulation of pranlukast hemihydrate with improved dissolution and oral bioavailability using a surface-modified microparticle. Based on solubility measurements, surface-modified pranlukast hemihydrate microparticles were manufactured using the spray-drying method with hydroxypropylmethyl cellulose, sucrose laurate, and water and without the use of an organic solvent. The hydrophilicity of the surface-modified pranlukast hemihydrate microparticle increased, leading to enhanced dissolution and oral bioavailability of pranlukast hemihydrate without a change in crystallinity. The surface-modified microparticles with an hydroxypropylmethyl cellulose/sucrose laurate ratio of 1:2 showed rapid dissolution of up to 85% within 30 minutes in dissolution medium (pH 6.8 and oral bioavailability higher than that of the commercial product, with approximately 2.5-fold and 3.9-fold increases in area under the curve (AUC0→12 h and peak plasma concentration, respectively. Therefore, the surface-modified microparticle is an effective oral drug delivery system for the poorly water-soluble therapeutic pranlukast hemihydrate. Keywords: solubility, wettability, sucrose laurate, cellulose

  15. High aspect ratio AFM Probe processing by helium-ion-beam induced deposition.

    Science.gov (United States)

    Onishi, Keiko; Guo, Hongxuan; Nagano, Syoko; Fujita, Daisuke

    2014-11-01

    A Scanning Helium Ion Microscope (SHIM) is a high resolution surface observation instrument similar to a Scanning Electron Microscope (SEM) since both instruments employ finely focused particle beams of ions or electrons [1]. The apparent difference is that SHIMs can be used not only for a sub-nanometer scale resolution microscopic research, but also for the applications of very fine fabrication and direct lithography of surfaces at the nanoscale dimensions. On the other hand, atomic force microscope (AFM) is another type of high resolution microscopy which can measure a three-dimensional surface morphology by tracing a fine probe with a sharp tip apex on a specimen's surface.In order to measure highly uneven and concavo-convex surfaces by AFM, the probe of a high aspect ratio with a sharp tip is much more necessary than the probe of a general quadrangular pyramid shape. In this paper we report the manufacture of the probe tip of the high aspect ratio by ion-beam induced gas deposition using a nanoscale helium ion beam of SHIM.Gas of platinum organic compound was injected into the sample surface neighborhood in the vacuum chamber of SHIM. The decomposition of the gas and the precipitation of the involved metal brought up a platinum nano-object in a pillar shape on the normal commercial AFM probe tip. A SHIM system (Carl Zeiss, Orion Plus) equipped with the gas injection system (OmniProbe, OmniGIS) was used for the research. While the vacuum being kept to work, we injected platinum organic compound ((CH3)3(CH3C5H4)Pt) into the sample neighborhood and irradiated the helium ion beam with the shape of a point on the apex of the AFM probe tip. It is found that we can control the length of the Pt nano-pillar by irradiation time of the helium ion beam. The AFM probe which brought up a Pt nano-pillar is shown in Figure 1. It is revealed that a high-aspect-ratio Pt nano-pillar of ∼40nm diameter and up to ∼2000 nm length can be grown. In addition, for possible heating

  16. Please Don't Stop the Music: Song Completion in Patients with Aphasia

    Directory of Open Access Journals (Sweden)

    Anna Victoria Kasdan

    2015-05-01

    Full Text Available Introduction: Many patients with aphasia, particularly those with nonfluent aphasia, have been observed to be able to sing the lyrics of songs more easily than they can speak the same words (Wan et al., 2010. The observation that not only singing, but even intoning words, can facilitate speech output in nonfluent aphasia patients provided the foundation for Melodic Intonation Therapy (MIT; Sparks, 1974, an intensive therapy lasting ten or more weeks (Schlaug et al., 2008. The current study aims to look at patients with aphasia in their ability to complete song lyrics by either singing, speaking, or humming them. Methods: Thus far, 11 patients with aphasia and 6 age- matched healthy controls have participated in an experimental stem-completion task examining singing abilities. The task consists of three conditions each consisting of 20 well-known songs and all participants completed all three conditions. Participants heard the first half of a phrase that was either sung in its original format (e.g., “Mary had a Little Lamb”, spoken, or intoned on the syllable “bum”, and were asked to complete the phrase according to the format in which the stimulus was presented, (i.e., either by singing, speaking the words, or humming/singing the melody correspondingly. The task was untimed, though most finished the task within an hour. Each participant completed a survey about their musical experience. Results: Patients were scored on their ability to complete the melody and words together in the sung condition, only the words in the spoken condition, and only the tune of the song in the melody condition. A parametric t-test indicated no significant difference between groups in the sung condition (mean patients=45.3%, mean controls=68.2%, t-value= -1.96, p=0.0684, though this test almost reached significance. There was also no significant difference between groups in the melody condition (mean patients= 18.2%, mean controls=20.0%, t-value= -0.335, p=0

  17. NMR, MRI, and spectroscopic MRI in inhomogeneous fields

    Science.gov (United States)

    Demas, Vasiliki; Pines, Alexander; Martin, Rachel W; Franck, John; Reimer, Jeffrey A

    2013-12-24

    A method for locally creating effectively homogeneous or "clean" magnetic field gradients (of high uniformity) for imaging (with NMR, MRI, or spectroscopic MRI) both in in-situ and ex-situ systems with high degrees of inhomogeneous field strength. THe method of imaging comprises: a) providing a functional approximation of an inhomogeneous static magnetic field strength B.sub.0({right arrow over (r)}) at a spatial position {right arrow over (r)}; b) providing a temporal functional approximation of {right arrow over (G)}.sub.shim(t) with i basis functions and j variables for each basis function, resulting in v.sub.ij variables; c) providing a measured value .OMEGA., which is an temporally accumulated dephasing due to the inhomogeneities of B.sub.0({right arrow over(r)}); and d) minimizing a difference in the local dephasing angle .phi.({right arrow over (r)},t)=.gamma..intg..sub.0.sup.t{square root over (|{right arrow over (B)}.sub.1({right arrow over (r)},t')|.sup.2+({right arrow over (r)}{right arrow over (G)}.sub.shimG.sub.shim(t')+.parallel.{right arrow over (B)}.sub.0({right arrow over (r)}).parallel..DELTA..omega.({right arrow over (r)},t'/.gamma/).sup.2)}dt'-.OMEGA. by varying the v.sub.ij variables to form a set of minimized v.sub.ij variables. The method requires calibration of the static fields prior to minimization, but may thereafter be implemented without such calibration, may be used in open or closed systems, and potentially portable systems.

  18. Toward imaging the body at 10.5 tesla.

    Science.gov (United States)

    Ertürk, M Arcan; Wu, Xiaoping; Eryaman, Yiğitcan; Van de Moortele, Pierre-François; Auerbach, Edward J; Lagore, Russell L; DelaBarre, Lance; Vaughan, J Thomas; Uğurbil, Kâmil; Adriany, Gregor; Metzger, Gregory J

    2017-01-01

    To explore the potential of performing body imaging at 10.5 Tesla (T) compared with 7.0T through evaluating the transmit/receive performance of similarly configured dipole antenna arrays. Fractionated dipole antenna elements for 10.5T body imaging were designed and evaluated using numerical simulations. Transmit performance of antenna arrays inside the prostate, kidneys and heart were investigated and compared with those at 7.0T using both phase-only radiofrequency (RF) shimming and multi-spoke pulses. Signal-to-noise ratio (SNR) comparisons were also performed. A 10-channel antenna array was constructed to image the abdomen of a swine at 10.5T. Numerical methods were validated with phantom studies at both field strengths. Similar power efficiencies were observed inside target organs with phase-only shimming, but RF nonuniformity was significantly higher at 10.5T. Spokes RF pulses allowed similar transmit performance with accompanying local specific absorption rate increases of 25-90% compared with 7.0T. Relative SNR gains inside the target anatomies were calculated to be >two-fold higher at 10.5T, and 2.2-fold SNR gain was measured in a phantom. Gradient echo and fast spin echo imaging demonstrated the feasibility of body imaging at 10.5T with the designed array. While comparable power efficiencies can be achieved using dipole antenna arrays with static shimming at 10.5T; increasing RF nonuniformities underscore the need for efficient, robust, and safe parallel transmission methods. Magn Reson Med 77:434-443, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  19. Neural substrates for semantic memory of familiar songs: is there an interface between lyrics and melodies?

    Directory of Open Access Journals (Sweden)

    Yoko Saito

    Full Text Available Findings on song perception and song production have increasingly suggested that common but partially distinct neural networks exist for processing lyrics and melody. However, the neural substrates of song recognition remain to be investigated. The purpose of this study was to examine the neural substrates involved in the accessing "song lexicon" as corresponding to a representational system that might provide links between the musical and phonological lexicons using positron emission tomography (PET. We exposed participants to auditory stimuli consisting of familiar and unfamiliar songs presented in three ways: sung lyrics (song, sung lyrics on a single pitch (lyrics, and the sung syllable 'la' on original pitches (melody. The auditory stimuli were designed to have equivalent familiarity to participants, and they were recorded at exactly the same tempo. Eleven right-handed nonmusicians participated in four conditions: three familiarity decision tasks using song, lyrics, and melody and a sound type decision task (control that was designed to engage perceptual and prelexical processing but not lexical processing. The contrasts (familiarity decision tasks versus control showed no common areas of activation between lyrics and melody. This result indicates that essentially separate neural networks exist in semantic memory for the verbal and melodic processing of familiar songs. Verbal lexical processing recruited the left fusiform gyrus and the left inferior occipital gyrus, whereas melodic lexical processing engaged the right middle temporal sulcus and the bilateral temporo-occipital cortices. Moreover, we found that song specifically activated the left posterior inferior temporal cortex, which may serve as an interface between verbal and musical representations in order to facilitate song recognition.

  20. Impression technique for a complete-arch prosthesis with multiple implants using additive manufacturing technologies.

    Science.gov (United States)

    Revilla-León, Marta; Sánchez-Rubio, José Luis; Oteo-Calatayud, Jesús; Özcan, Mutlu

    2017-06-01

    This article describes an impression technique for a complete-arch prosthesis supported by multiple implants where additive manufacturing technologies were used to fabricate a splinting framework and a custom tray. The technique presented uses a shim method to control the homogenous splinting acrylic resin and impression material during the procedure, thereby reducing laboratory and chairside time and the number of impression copings and laboratory analogs needed. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  1. OVERALL CONTROL SYSTEM FOR HIGH FLUX PILE

    Science.gov (United States)

    Newson, H.W.; Durham, N.C.; Wigner, E.P.; Princeton, N.J.; Epler, E.P.

    1961-05-23

    A control system is given for a high fiux reactor incorporating an anti- scram control feature whereby a neutron absorbing control rod acts as a fine adjustment while a neutron absorbing shim rod, actuated upon a command received from reactor period and level signals, has substantially greater effect on the neutron level and is moved prior to scram conditions to alter the reactor activity before a scram condition is created. Thus the probability that a scram will have to be initiated is substantially decreased.

  2. Psychophysiological patterns related to individual zone optimal performance in self-paced task: a step forward with map model

    OpenAIRE

    2014-01-01

    Tese de Doutoramento em Ciências do Desporto Nas últimas décadas, a análise de fatores psicológicos, fisiológicos, cinestésicos e comportamentais tem sido amplamente investigada, sobretudo em desportos de precisão (e.g.,Goodman, Haufler, Shim, & Hatfield, 2009; Hatfield & Kerick, 2007). Uma perspectiva multifatorial e multidimensional baseada em vários campos de conhecimento (e.g., comportamento motor, psicologia do desporto e psico-fisiologia) vem sendo utilizada na análise de experiên...

  3. Engagement of Metal Debris into a Gear Mesh

    Science.gov (United States)

    Handschuh, Robert F.; Krantz, Timothy L.

    2010-01-01

    A series of bench top experiments was conducted to determine the effects of metallic debris being dragged through meshing gear teeth. A test rig that is typically used to conduct contact fatigue experiments was used for these tests. Several sizes of drill material, shim stock, and pieces of gear teeth were introduced and then driven through the meshing region. The level of torque required to drive the "chip" through the gear mesh was measured. From the data gathered, chip size sufficient to jam the mechanism can be determined.

  4. Engagement of Metal Debris into Gear Mesh

    Science.gov (United States)

    handschuh, Robert F.; Krantz, Timothy L.

    2010-01-01

    A series of bench-top experiments was conducted to determine the effects of metallic debris being dragged through meshing gear teeth. A test rig that is typically used to conduct contact fatigue experiments was used for these tests. Several sizes of drill material, shim stock and pieces of gear teeth were introduced and then driven through the meshing region. The level of torque required to drive the "chip" through the gear mesh was measured. From the data gathered, chip size sufficient to jam the mechanism can be determined.

  5. The physics design of magnet in 14 MeV cyclotron

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The 14 MeV, 400 μA compact cyclotron is under construction at China Institute of Atomic Energy (CIAE). The design of main magnet and the result of beam dynamics in the cyclotron will be described in this paper, including the choice of main parameters of magnet, the method of shimming isochronous field in the compact cyclotron and optimization of the magnetic field in central region. The beam will be accelerated to 14.6 MeV by optimizing the magnet structure.

  6. Tile Calorimete Pre-Assembly Summary and Barrel Assembly Plan

    CERN Document Server

    Proudfoot, J; Liablin, M V; Topilin, N D

    2004-01-01

    The barrel survey results from the pre-assembly in Building 185 are reviewed. From these and the models developed to calculate the cylinder geometry we propose a minimal modification to the shimming plan for the barrel calorimeter assembly in the Atlas cavern. At the precision of this calculation, we expect the tile calorimeter to be almost entirely within it design envelope. The focus of this note is the radial envelope. Based on the pre-assembly experience the tile calorimeter will fit comfortably within its envelope along the beam line.

  7. Active and passive compensation of APPLE II-introduced multipole errors through beam-based measurement

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Ting-Yi; Huang, Szu-Jung; Fu, Huang-Wen; Chang, Ho-Ping; Chang, Cheng-Hsiang [National Synchrotron Radiation Research Center, Hsinchu Science Park, Hsinchu 30076, Taiwan (China); Hwang, Ching-Shiang [National Synchrotron Radiation Research Center, Hsinchu Science Park, Hsinchu 30076, Taiwan (China); Department of Electrophysics, National Chiao Tung University, Hsinchu 30050, Taiwan (China)

    2016-08-01

    The effect of an APPLE II-type elliptically polarized undulator (EPU) on the beam dynamics were investigated using active and passive methods. To reduce the tune shift and improve the injection efficiency, dynamic multipole errors were compensated using L-shaped iron shims, which resulted in stable top-up operation for a minimum gap. The skew quadrupole error was compensated using a multipole corrector, which was located downstream of the EPU for minimizing betatron coupling, and it ensured the enhancement of the synchrotron radiation brightness. The investigation methods, a numerical simulation algorithm, a multipole error correction method, and the beam-based measurement results are discussed.

  8. Construction Progress of CYCIAE-100

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Tian-jue; LV; Yin-long; JI; Bin; YI; Hui

    2012-01-01

    <正>It has been a very productive year for the BRIF project in 2012, with focus on the fabrication of major equipments and installation. A number of large scale equipments have been ready for onsite installation, including the main magnet of CYCIAE-100, the main coils, hydraulic elevating system, magnetic mapper, RF amplifiers, etc. Meanwhile, a series of work has started as well, among which are the magnetic mapping and shimming, power test and debugging of the RF amplifiers, as well as other key equipments of subsystems.

  9. Development of a Quasi-Periodic Undulator for the HLS

    CERN Document Server

    Yang, Yufeng; Chen, Wan; Jia, Qika; Sun, Shuchen; Li, Zhiqiang

    2014-01-01

    China's first quasi-periodic undulator (QPU) has been developed for the Hefei Light Source (HLS). It uses a magnetic configuration with varied thicknesses of NdFeB blocks, based on the QPU of European Synchrotron Radiation Facility (ESRF). Depression of 3rd harmonic radiation is significantly improved over the ESRF QPU, as deduced from the measured magnetic fields. A method of configuring shims of different geometries and sizes, based on a symmetric principle to correct multi-pole field integrals, was demonstrated.

  10. European League Against Rheumatism recommendations for terminology and diagnosis of calcium pyrophosphate crystal deposition disease: An expert's comments

    Directory of Open Access Journals (Sweden)

    Viktoriya Georgievna Barskova

    2011-09-01

    Full Text Available V etoy stat'e my provodim obsuzhdenie 9 rekomendatsiy, kotorye razrabotany standartnym metodom sochetaniya dokazatel'nykh issledovaniy i konsensusa ekspertov. V svyazi s bol'shim spektrom klinicheskikh fenotipov deponirovaniya kristallov pirofosfata kal'tsiya (PFK terapiya bolezni predstavlyaet slozhnuyu zadachu, tem bolee chto, v otlichie ot podagry, v nastoyashchee vremya net spetsificheskoy terapii, sposobstvuyushchey ischeznoveniyu PFK. Poetomu lechenie sfokusirovano na kontrole klinicheskikh simptomov kak ostrogo, tak i khronicheskogo artrita. Ispol'zuyutsya podkhody, analogichnye takovym pri terapii ostrogo podagricheskogo artrita, kontrole boli i simptomov pri osteoartroze (OA.

  11. European League Against Rheumatism recommendations for terminology and diagnosis of calcium pyrophosphate crystal deposition disease: An expert's comments

    Directory of Open Access Journals (Sweden)

    Viktoriya Georgievna Barskova

    2011-01-01

    Full Text Available V etoy stat'e my provodim obsuzhdenie 9 rekomendatsiy, kotorye razrabotany standartnym metodom sochetaniya dokazatel'nykh issledovaniy i konsensusa ekspertov. V svyazi s bol'shim spektrom klinicheskikh fenotipov deponirovaniya kristallov pirofosfata kal'tsiya (PFK terapiya bolezni predstavlyaet slozhnuyu zadachu, tem bolee chto, v otlichie ot podagry, v nastoyashchee vremya net spetsificheskoy terapii, sposobstvuyushchey ischeznoveniyu PFK. Poetomu lechenie sfokusirovano na kontrole klinicheskikh simptomov kak ostrogo, tak i khronicheskogo artrita. Ispol'zuyutsya podkhody, analogichnye takovym pri terapii ostrogo podagricheskogo artrita, kontrole boli i simptomov pri osteoartroze (OA.

  12. Design of the KOSMOS oil-coupled spectrograph camera lenses

    CERN Document Server

    O'Brien, Thomas P; Martini, Paul; Poczulp, Gary

    2014-01-01

    We present the design details of oil-coupled lens groups used in the KOSMOS spectrograph camera. The oil-coupled groups use silicone rubber O-rings in a unique way to accurately center lens elements with high radial and axial stiffness while also allowing easy assembly. The O-rings robustly seal the oil within the lens gaps to prevent oil migration. The design of an expansion diaphragm to compensate for differential expansion due to temperature changes is described. The issues of lens assembly, lens gap shimming, oil filling and draining, bubble mitigation, material compatibility, mechanical inspection, and optical testing are discussed.

  13. Threshold Corrosion Fatigue of Welded Shipbuilding Steels.

    Science.gov (United States)

    1992-01-01

    of a deposit composition equivalent to the. L-TEC 95 solid electrode produced welds of similar tensile properties but of lower weld metal impact...toughness for welds produced with the powder-cored electrode of a deposit composition equivalent to the L-TEC 95 solid electrode was improved...consisting of a 5N H2SO 4 acid with 0.25 mg/i of arsenite (As2O3 ). Shims were placed in the electrospark discharge machined face-grooves and the

  14. Advanced High-Power Generator Research Program

    Science.gov (United States)

    1986-05-01

    l4 ~ 1 T- 14 SLOTS 5CALZ ’/A EQUALLY 574 SPACED 7 40 A: / / 4.0 DIA ~ A ~ ~I \\HIP SOND L.Qý - C4 𔃿CALE- DIA THRUU SCALE.- F:ULL HEAT TREAT1 PER...devi- ation between slots of less than 0.001 in. (b) A dummy magnet with a 0.009-in, shim on each side was inserted into the slot. The height of the... dummy magnet was checked relative to the outer diameter of the poles. Readings ranged from 0.007 in. to 0.021 in. below the rotor outside diameter. It

  15. Girder deformation related phase errors on the undulators for the European X-Ray Free Electron Laser

    Directory of Open Access Journals (Sweden)

    Yuhui Li

    2015-06-01

    Full Text Available In long gap tunable undulators, strong magnetic forces always lead to some amount of gap-dependent girder deformation and resulting gap-dependent phase errors. For the undulators for the European XFEL, this problem has been investigated thoroughly and quantitatively. Using the different gap dependencies of suitable shims and pole height tuning, a method is presented which can be applied to reduce the overall gap dependence of the phase error if needed. It is exemplified by tuning one of the undulator segments for the European X-Ray Free Electron Laser back to specs.

  16. EPU correction scheme study at the CLS

    Energy Technology Data Exchange (ETDEWEB)

    Bertwistle, Drew, E-mail: drew.bertwistle@lightsource.ca; Baribeau, C.; Dallin, L.; Chen, S.; Vogt, J.; Wurtz, W. [Canadian Light Source Inc. 44 Innovation Boulevard, Saskatoon, SK S7N 2V3 (Canada)

    2016-07-27

    The Canadian Light Source (CLS) Quantum Materials Spectroscopy Center (QMSC) beamline will employ a novel double period (55 mm, 180 mm) elliptically polarizing undulator (EPU) to produce photons of arbitrary polarization in the soft X-ray regime. The long period and high field of the 180 mm period EPU will have a strong dynamic focusing effect on the storage ring electron beam. We have considered two partial correction schemes, a 4 m long planar array of BESSY-II style current strips, and soft iron L-shims. In this paper we briefly consider the implementation of these correction schemes.

  17. PERSISTENT CURRENT EFFECT IN 15-16 T NB3SN ACCELERATOR DIPOLES AND ITS CORRECTION

    Energy Technology Data Exchange (ETDEWEB)

    Kashikhin, V. V. [Fermilab; Zlobin, A. V. [Fermilab

    2016-11-08

    Nb3Sn magnets with operating fields of 15-16 T are considered for the LHC Energy Doubler and a future Very High Energy pp Collider. Due to large coil volume, high critical current density and large superconducting (SC) filament size the persistent current effect is very large in Nb3Sn dipoles al low fields. This paper presents the results of analysis of the persistent current effect in the 15 T Nb3Sn dipole demonstrator being developed at FNAL, and describes different possibilities of its correction including passive SC wires, iron shims and coil geometry.

  18. Rendezvous and docking with remote piloted vehicles

    Science.gov (United States)

    Micheal, J. D.

    The man-in-the-loop control system requirements for the Orbital Maneuvering Vehicle (OMV) are examined. Since many similarities exist between the Teleoperator Retrieval System (TRS) and the unfolding OMV concept, a review of the TRS control system baseline along with selected design trades which led to that baseline are discussed. TRS program issues relevant to the man-in-the-loop control system design include thruster size, communication delays and TV bandwidth compression, range/range rate radar, tumbling targets, shimmed docking interface, and control system definition. A TRS vs. OMV simulation comparative study is summarized, and the major issues currently facing the control system designer on OMV are discussed.

  19. JPRS Report: Proliferation Issues

    Science.gov (United States)

    2016-03-24

    on May signed a cultural agreement with Chinese Culture Min- 20 promised his Israeli counterpart Shim’on Peres that ister Liu Zhongde, and visited...reporters, said he "cannot but be disappointed" if nominate Hans Blix of Sweden for a fourth four-year Monday’s statement reflected the U.S. Government’s...pora views the embassy as a kind of center of political, Dwelling in detail on the results of the visit by the U.S. economic, cultural , and legal

  20. North Korea and Support to Terrorism: An Evolving History

    Directory of Open Access Journals (Sweden)

    Bruce E. Bechtol, Jr.

    2010-01-01

    Full Text Available The DPRK's (Democratic People's Republic of Korea or North Korea support for terrorism began as an ideologically-based policy financed by the Soviet Union that eventually led to a policy designed to put money into the coffers of the elite in Pyongyang—in short, a "proliferation for hire" policy. This article articulates a brief history of the North Korean regime, the rise to power of Kim Il-sung and his son, Kim Jong-il, and North Korea's persistent support to terrorist groups around the globe.

  1. Pronunciation and Articulation for Singing Chinese Works

    Institute of Scientific and Technical Information of China (English)

    郑菲菲

    2013-01-01

    For singing Chinese works, pronunciation and articulation are the most essential and the most crucial factors. Their beginning should be brief, middle should be melodious and long-lasting, and end should be as clear and crisp as crystal. Considering from pronunciations, Chinese works can be divided into two categories:one is comprehensive style emphasizing clear enunciation; the other is local folk song that should be sung based on corresponding local accent of the works. Besides, based on correct pronunciation and articulation, balance between pro-nunciation and articulation should be achieved, both the essence of western traditional mode of singing and Chinese traditional music should be followed and inherited.

  2. OMX - a novel high speed and high resolution microscope and its application to nuclear and chromosomal structure analysis

    OpenAIRE

    Haase, Sebastian

    2008-01-01

    Im Rahmen dieser Arbeit wurde ein neuartiges 3D Fluoreszenz Mikroskop, OMX gennant, entworfen und gebaut. Ein umfassender Design-Neuansatz erlaubt es den neuen Anforderungen der aktuellen Biologie bezüglich erhöhter Auflösung in Zeit und Raum Rechnung zu tragen. Mit Ausnahme vom Auflegen des Objektträgers sind alle Aspekte des Mikroskops Computer-gesteuert. Einen Großteil der Software floß in ein neues, eigenständiges Open-Source Projekt ein. Es erlaubt die Verarbeitung sehr großer, ...

  3. Observation of a strong interplanar electric field in a dynamical diffraction of polarized neutrons

    Science.gov (United States)

    Alexeev, V. L.; Fedorov, V. V.; Lapin, E. G.; Leushkin, E. K.; Rumiantsev, V. L.; Sumbaev, O. I.; Voronin, V. V.

    1989-11-01

    The first experimental study of the Schwinger interaction of polarized neutrons with an electric field of a noncentrosymmetric perfect crystal (α-quartz) was made for two wave dynamical diffraction. Phase shifts of Pendellösung fringes for two different spin to crystal field orientations were measured. The theory of the effect is given. The calculated value of SiO2 (11 overline20) interplanar electr field, seen by the diffracted neutron, is 2.1 × 10 8 V/cm. This is in good agreement with the experimental result: (1.8 ± 0.3) × 10 8 V/cm.

  4. Hydroxyethylstärke (HES) im Urin nach Mehrfachinfusion von HES (450/0,7) : physiko-chemische Veränderungen der Substanzcharakteristika einer hochsubstituierten, hochmolekularen HES

    OpenAIRE

    Lesch, Alexander

    2004-01-01

    Die bei verschiedenen klinischen Indikationen, wie beispielsweise als Volumenersatz oder zur Hämodilution, eingesetzte Hydroxyethylstärke wird vorwiegend über das Molekulargewicht und, sachlich richtiger, über die molare Substitution charakterisiert. In neueren Publikationen wurde die Beachtung der Substituentenverteilung, das C2/C6- Verhältnis, als zusätzliches Merkmal gefordert. Ferner sollten nicht die Parameter der Ausgangslösung, sondern die "in vivo- Merkmale" als maßgeblich für die Cha...

  5. A Forest of Lines: An Interview with Pierre Huyghe

    Directory of Open Access Journals (Sweden)

    Amelia Douglas

    2008-12-01

    Full Text Available Interview between Amelia Douglas and Pierre HuygheAmelia Douglas: For the 2008 Biennale of Sydney, you constructed a temporary forest of a thousand trees, real trees, inside the concert hall at the Sydney Opera House. A song was sung in the forest, and the audience was invited to walk through this space filled with mist, through paths in the trees, to listen to a story. First, why did you want to use the Opera House in particular for this work? Pierre Huyghe: I was looking for a place of representation. When you think about theatre, spectacle, opera, you think about this place and this iconic building.

  6. Wave front sensor based on digital mirror matrix for functional characterization of freeform ophthalmic optics

    CERN Document Server

    Stürwald, Stephan

    2015-01-01

    In dieser Arbeit wird die Entwicklung und Charakterisierung eines Wellenfrontmesssystems für Gleitsichtbrillengläser beschrieben. Es ermöglicht eine quantitative Messung der Wellenfront bis zu 65 mm Durchmesser mit einer lateralen Auflösung von besser als die erforderlichen 1mm für die Inline-Qualitätskontrolle in der Produktion. Das realisierte Low-Cost System ist für Wellenfrontsteigungen mit einer sphärischen Abweichung von ± 2 Grad konzipiert und eröffnet eine flexible funktionale Prüfung von optischen Systemen und Freiformoptiken.

  7. Areeni aasta albumid 2004

    Index Scriptorium Estoniae

    2004-01-01

    Heliplaatidest: Franz Ferdinand "Franz Ferdinand", Toe Tag "Legendaarne", The Libertines "The Libertines ", Morrissey "You Are The Qarry", The Streets "A Grand Don't Come For Free", Kalm "Generalissimus Kalm", Brian Wilson "Smile", Madvillain "Madvillainy", Scissor Sisters "Scissor Sisters", Gary Wilson "Mary Had A Brown Hair", Animal Collective "Sung Tongs", Keane "Hopes And Fears", Todd Rundgren "Liars", Nick Cave & The Bad Seeds "Abbatoir Blues/The Lyre of Orpheus", Mylo "Destroy Rock'n'Roll", Devendra Banhart "Rejoicing In The Hands", Stefani "Love Angel Music Baby", Björk "Medulla", Moodymann "Black Mahogani"

  8. Kein Fahrplan für den Frieden: Erdogans Demokratiepaket enttäuscht kurdische Erwartungen

    OpenAIRE

    Kurban, Dilek

    2013-01-01

    Viele hatten weitaus mehr von dem »Demokratiepaket« erwartet, das der türkische Premierminister Recep Tayyip Erdogan am 30. September angekündigt hatte. Schließlich wurde es fast ein Jahr nach Aufnahme der informellen Friedensgespräche beschlossen, die die Regierung mit Abdullah Öcalan führt, dem inhaftierten Führer der Arbeiterpartei Kurdistans (PKK). Doch anstelle von Reformen zur Lösung der Kurdenfrage stellte Erdogan lediglich allgemeine Maßnahmen in Aussicht, die dazu dienen sollen, türk...

  9. The Particle Physicists’ Song : the CERN Choir in full voice in the CERN Control Centre, with writer Danuta Orlowska

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    The song was submitted to CERN Courier by Danuta Orlowska, a clinical psychologist with Guy’s and St Thomas’ NHS Foundation Trust in London. It is written to be sung to the tune of The Hippopotamus Song, by Michael Flanders and Donald Swann, which will be well known to many British readers. On 3 February, members of the CERN choir gathered to give a rendition in the CERN Control Centre – the nerve centre of the LHC, which lies at the heart of the lyrics.

  10. Some Computational Aspects of the Brain Computer Interfaces Based on Inner Music

    Science.gov (United States)

    Klonowski, Wlodzimierz; Duch, Wlodzisław; Perovic, Aleksandar; Jovanovic, Aleksandar

    2009-01-01

    We discuss the BCI based on inner tones and inner music. We had some success in the detection of inner tones, the imagined tones which are not sung aloud. Rather easily imagined and controlled, they offer a set of states usable for BCI, with high information capacity and high transfer rates. Imagination of sounds or musical tunes could provide a multicommand language for BCI, as if using the natural language. Moreover, this approach could be used to test musical abilities. Such BCI interface could be superior when there is a need for a broader command language. Some computational estimates and unresolved difficulties are presented. PMID:19503802

  11. Vorgehensmodelle und Prozesse für die Entwicklung von Produkten und Dienstleistungen

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup

    2005-01-01

    Vorgehensschritten. Die Definition von gewissen Vorgehensschritten bedeutet, dass die Route, auf welcher das Entwicklungsziel erreicht werden soll, bereits zu einem gewissen Grad geklärt ist. Nur durch die menschlichen Fähigkeiten zur Strategieentwicklung und Problemlösung wird schliesslich klas, wie das Ziel...... unternehmensspezifische Prozedur sein? Wie wird die Prozedur auf das Unternehmen angepasst und wie entsteht daraus ein Projektplan, der das Projekt optimal unterstützt? In diesem Kapitel werden Vorgehensmodelle und Prozeduren als wesentliche Instrumente für die Durchführung von Produktentwicklungsprojekten dargestellt...

  12. Identification and characterization of a cyanate permease in Escherichia coli K-12.

    OpenAIRE

    Sung, Y C; Fuchs, J A

    1989-01-01

    Escherichia coli contains an inducible enzyme, cyanase, that catalyzes the decomposition of cyanate into ammonia and bicarbonate. The gene encoding cyanase, cynS, was cloned and found to be on a DNA fragment that contained the lac operon. Characterization of a plasmid encoding cyanase indicated that a 26-kilodalton (kDa) protein of unknown function was also induced by cyanate (Y-C. Sung, D. Parsell, P.M. Anderson, and J.A. Fuchs, J. Bacteriol. 169:2639-2642, 1987). The gene encoding the 26-kD...

  13. Neurophysiological Bases of Event-Related Potentials.

    Science.gov (United States)

    1984-06-01

    1% l ; CosM -TR. 84i69 0 UIUOTIOLOGICAL MUS OF Annual Report ft. 23 is񓑜AD-A 148 482 sung 1804 -- by: Cberlee S. Robert ad itchael 3. Hennesey OPP...being recorded In the standard 23 mg/kg -50 ga CAL 33.3 gay 0.0 50OAV 0.2 JfKW. 56.7 INy 0.3 1. .5 . Tone Light LA-4373-6 FIGURE 8 DOSE-RELATED EFFECTS

  14. 古城新韵:醇香可口的平遥牛肉

    Institute of Scientific and Technical Information of China (English)

    张恩

    2003-01-01

    “Pingyao's beef and Taigu's pancakes”——thus begins the opening line of the lyric of “In Praise of Local Produce” sung by Guo Lanying, a famous soprano. Thanks to this song, the fame of Pingyao beef has reached far and wide. Always the tender cut, Pingyao beef tastes juicy but not greasy, chewy but not dry, achieving the right balance. Usually wok-braised for over 12 hours, Pingyao beef makes a delighlfully tasty dish rich in nutrition. And along with the photo festival, more and more visitors will get to know Pingyao beef and more and more people will take a liking to it.

  15. Prediction by data mining, of suicide attempts in Korean adolescents: a national study

    OpenAIRE

    Bae SM; Lee SA; Lee SH

    2015-01-01

    Sung Man Bae,1 Seung A Lee,2 Seung-Hwan Lee2,3 1Department of Counseling Psychology, The Cyber University of Korea, Seoul, South Korea; 2Clinical Emotion and Cognition Research Laboratory, Goyang, South Korea; 3Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea Objective: This study aimed to develop a prediction model for suicide attempts in Korean adolescents.Methods: We conducted a decision tree analysis of 2,754 middle and hig...

  16. 韩国利用Scopus数字广播平台传送CNN和MTV

    Institute of Scientific and Technical Information of China (English)

    宋伟

    2001-01-01

    @@ Scopus网络技术有限公司是世界上优秀的数字压缩设备的供应商之一.它于近期宣布:SamSungUnitel Korea公司正在使用其前端的数字广播系统在韩国播出CNN和MTV.在此项目上,Scopus公司与韩国Dong-In卫星网络公司合作,同时这也是Scopus公司在朝鲜半岛所做的第一个大项目.

  17. Brazilian National Anthem presenting as musical hallucination: A case report with 9-year follow-up

    Directory of Open Access Journals (Sweden)

    José Eduardo Martinelli

    Full Text Available ABSTRACT Musical hallucination is a type of complex auditory hallucination. Possible etiologies are deafness, psychiatric disorders such as schizophrenia, major depression, use of medication and stress, besides neurologic diseases including epilepsy, stroke and cancer. Uncommon etiologies encompass infectious diseases, metabolic disorders, and sensory deprivation. Although musical hallucinations have a major impact on patients' lives, they have been undervalued and understudied in the literature. We report a case of a 79-year-old woman with musical hallucination (hearing a sung National anthem without cognitive impairment or hearing loss. The patient had preserved insight of her complaint and responded well to neuroleptics.

  18. Factors associated with group bullying and psychopathology in elementary school students using child-welfare facilities

    OpenAIRE

    Kim JW; Lee K; YS; Lee; Han DH; Min KJ; Song SH; Park GN; Lee JY; Kim JO

    2015-01-01

    Jun Won Kim,1,2 KounSeok Lee,3 Young Sik Lee,4 Doug Hyun Han,4 Kyung Joon Min,4 Sung Hwan Song,5 Ga Na Park,6 Ju Young Lee,1 Jae Ock Kim5 1Division of Child and Adolescent Psychiatry, Department of Neuropsychiatry, College of Medicine, Seoul National University, Seoul, South Korea; 2Department of Psychiatry, Graduate School, Chung-Ang University, Seoul, South Korea; 3Department of Psychiatry, Samsung Medical Center, Seoul, South Korea; 4Department of Psychiatry, Chung-Ang University, College...

  19. Mechanisms of alveolar protein clearance in isolated rabbit lungs : role of clathrin- and caveolae-mediated endocytosis of albumin by the alveolar epithelium

    OpenAIRE

    Rummel, Sebastian

    2007-01-01

    Die Entstehung einer proteinreiche Ödemflüssigkeit in den Alveolen ist eine Hauptkomponente im Rahmen der Erkrankung Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS), welche zu einer massiven Einschränkung des Gasaustausches führt. Der onkotische Druck im Alveolus steigt massiv an, hält vermehrt Wasser in den Alveolen zurück und die Situation verschlimmert sich weiter. Die Auflösung des Ödems und die Verminderung der Proteinkonzentration sind also wichtigste Punkte für das Übe...

  20. Discovery as Basic Methodology of Qualitative and Quantitative Research

    OpenAIRE

    Gerhard Kleining; Harald Witt

    2001-01-01

    Der Aufsatz schlägt vor, (1.) dass Forschungsmethodologien in der Psychologie und den Sozialwissenschaften auf Entdeckungen zielen sollten statt auf Deutung und Interpretationen. Er bewertet Hermeneutik und das "interpretative Paradigma" kritisch aus drei Gründen: der inhärenten Subjektivität, der Beschränkung auf Geisteswissenschaft oder die qualitative Datenform und der Tendenz zur Auflösung von Regeln in ihrer jüngsten Phase mit der Behauptung einer Krise der qualitativen Forschung (DENZIN...

  1. Entdeckung als Basismethodologie für qualitative und quantitative Forschung

    OpenAIRE

    Kleining, Gerhard; Witt, Harald

    2001-01-01

    Der Aufsatz schlägt vor, (1.) dass Forschungsmethodologien in der Psychologie und den Sozialwissenschaften auf Entdeckungen zielen sollten statt auf Deutung und Interpretationen. Er bewertet Hermeneutik und das "interpretative Paradigma" kritisch aus drei Gründen: der inhärenten Subjektivität, der Beschränkung auf Geisteswissenschaft oder die qualitative Datenform und der Tendenz zur Auflösung von Regeln in ihrer jüngsten Phase mit der Behauptung einer Krise der qualitativen Forschung (DENZIN...

  2. Reference: 710 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 710 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u18162593i Jung Choonkyun et al. 2008 Fe...ic stress tolerance of transgenic Arabidopsis overexpressing AtMYB44 was conferred by reduced expression of ...naling. Overexpression of AtMYB44 enhances stomatal closure to confer abiotic stress tolerance in transgenic... Arabidopsis. 2 623-35 18162593 2008 Feb Plant physiology Cheong Jong-Joo|Choi Yang Do|Han Sang Won|Jung Choonkyun|Kim Chung Ho|Koo Yeon Jong|Nahm Baek Hie|Seo Jun Sung|Song Sang Ik

  3. X-Ray Absorption Spectroscopy of Uranium Dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Tobin, J G

    2010-12-10

    After the CMMD Seminar by Sung Woo Yu on the subject of the x-ray spectroscopy of UO2, there arose some questions concerning the XAS of UO2. These questions can be distilled down to these three issues: (1) The validity of the data; (2) The monchromator energy calibration; and (3) The validity of XAS component of the figure shown. The following will be shown: (1) The data is valid; (2) It is possible to calibrate the monchromator; and (3) The XAS component of the above picture is correct. The remainder of this document is in three sections, corresponding to these three issues.

  4. Mit Mathematik zu Mehr Intelligenz in der Logistik

    Science.gov (United States)

    Möhring, Rolf H.; Schenk, Michael

    Die Lösung logistischer Probleme ist ein wichtiger Aspekt menschlichen Handelns seit Menschen gemeinsam zielgerichtet tätig wurden. Die Grundlagen dessen, was wir heute Logistik nennen, entstammen dem militärischen Bereich. So basierte z. B. das römische Imperium in starkem Maße auf militärisch-logistischen Glanzleistungen. Ob damals bereits mathematische Überlegungen eine Rolle spielten, wissen wir heute nicht. Jedoch versuchte z. B. Napoleon, der mit den bedeutendsten Mathematikern seiner Zeit befreundet war, den Transport seiner Truppen und die Verbreitung von Informationen zu optimieren und strategisch einzusetzen.1,2

  5. Invitation

    CERN Multimedia

    2004-01-01

    « DEUTSCHE MESSE » BY FRANZ SCHUBERT PERFORMED BY THE « WIENER SCHUBERTBUND » On the occasion of the Organization's Fiftieth Anniversary, Mr Hans-Walter Gérard Schober, Honorary Consul-General of Austria in Geneva, is pleased to invite all those working at CERN to a mass at which Franz Schubert's German Mass will be sung by the Vienna Schubert Choral Society. Sunday, 17 October 2004 at 11 a.m., Saint Joseph's Catholic Church, Place des Eaux-Vives, 1207 Geneva (the church has about 900 seats).

  6. THREE NEW SPECIES OF CRAMBINAE(LEPIDOPTERA : PYRALIDAE) IN CHINA

    Institute of Scientific and Technical Information of China (English)

    CHENTie-mei; SONGShi-mei; YUANDe-cheng

    2003-01-01

    Three new species of Crambinae from China, Eschata truncata Song & Chen, sp. nov., Eschata tricornia Song & Chen, sp. nov., Pseudargyria acuta Song & Chen, sp. nov. and the female of Girdharia tau-romma Kapur are described, with figures and illustrations of genitalia provided. E. truncata resembles E.smithi Bleszynski, but valva with one short truncated process in costa; E. tricornia differed from all recorded species by valva with a triangular process on dorsum; P. acuta resembles P. marginepunctalis (Hampson), but with cucullus rapidly pointed and aedeagus with one group of cornuti. E. bleszynskiella Minet is proposed as a junior synonym of E. shanghaiensis Wang & Sung.

  7. The Role that φ-Features Play in Long Distance Binding

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    .INTRODUCTIONThis article attempts to investigate long distance binding in Chinese under a feature- orientated ap-proach based on the studies done by Battistella ( 1 989) ,Tang ( 1 986) ,Cole and Sung ( 1 990 ) and oth-ers.The data presented in this article demonstrated,contrary to the prevailing assumption that- fea-tures of reflexives in various language are base generated,long distance reflexives before movement atL F have barren or impoverishedφ- features.On this basis,itis demonstrated thata reflexive ...

  8. Exploitation of the IMS and Other Data for a Comprehensive Advanced Analysis of the North Korean Nuclear Tests

    Science.gov (United States)

    2010-02-01

    98, No. 5, pp. 2498–2506, October 2008, doi: 10.1785/0120080929. Che, Il-Young, Tae Sung Kim, Jeong-Soo Jeon and Hee-Il Lee (2009) Infrasound...Workshop on Seismic Location and Discrimination in Korea, Phillips Lab Report PL-TR-96-2086, 313-322. Herrmann, R., Y. Jeon , H. Yoo, K. Cho, W. Walter, M...mb(Pn), mb(Lg) scales and transportability of the M0:mb discriminant to new tectonic regions,” Bull. Seism. Soc. Am., 87, 1083-1099. Richards, Paul

  9. Song type matching, song type switching and eavesdropping in male great tits

    DEFF Research Database (Denmark)

    Peake, Thomas More; Matessi, Giuliano; McGregor, Peter Kenneth

    2005-01-01

    by changing the timing of songs. We examined the phenomenon of song type matching by presenting male great tits, Parus major, with simulated interactions in which one interactant switched song type such that it matched (or not) that sung by the opponent. Subjects responded to simulated intrusion by previously...... switched song types but not matched. Male great tits are therefore capable of extracting different kinds of information by eavesdropping on interactions between others and using that information when deciding how to respond to subsequent intrusion. These results confirm and expand our knowledge...

  10. VizieR Online Data Catalog: X-ray study of the young cluster NGC6231 (Damiani+, 2016)

    Science.gov (United States)

    Damiani, F.; Micela, G.; Sciortino, S.

    2016-09-01

    X-ray properties of sources in the Chandra observations of NGC6231 (columns 1-13), and their identifications in the catalogs of Sung, Sana and Bessell (2013, Cat. J/AJ/145/37; SSB), VPHAS+ (Drew et al., 2014, Cat. J/MNRAS/440/2036), and 2MASS (Cat. II/246) (columns 14-25). The last five columns refer to membership, Hα or IR excess, mass and luminosity. Rows 1-1613 list X-ray candidate members, while rows 1614-1888 list additional candidate members from Hα or IR excess. (1 data file).

  11. Internationalisierung des Lehramts – eine Quadratur des Kreises? Zu Chancen und Grenzen eines grenzüberschreitenden Paradigmas der Lehrerbildung am Beispiel des Masterstudiengangs MEEF / LINT (Lehramt International Nizza-Regensburg

    Directory of Open Access Journals (Sweden)

    Jochen Mecke

    2016-03-01

    Full Text Available Die Internationalisierung ist nicht das Problem, sie ist die Lösung: In einer europäischen Gesellschaft, in der die Dynamik einer neuen Vielfalt derzeit eine der wenigen Konstanten darstellt, die nationenübergreifend Bestand hat und keine Grenzen kennt, brauchen wir eine Lehrerbildung, die strukturell und konzeptionell so gesamteuropäisch angelegt ist wie ihre Herausforderungen. Wir brauchen trotz und wegen verschiedener bildungspolitischer Unterschiede und Hürden neue Ansätze der Kooperation und Vernetzung, deren Chancen und Herausforderungen in der Folge exemplarisch am binationalen Master of Education MEEF / LINT (Lehramt International Deutsch-Französisch skizziert werden sollen.

  12. China and North Korea: A Peculiar Relationship

    Science.gov (United States)

    2011-03-01

    States and North Korea. Beijing played an interlocutor role via high-level visits, such as Chinese Foreign Minister Tang Jiaxuan’s visit to the...stability-or-status-quo-on-the-korean- peninsula/. 92 Sung-Yoon Lee, “Is Status Quo Destiny? China’s Interests in Post-Kim Dynasty Korea,”a presentation at...preferences will heavily impact that outcome). Tang Shiping, a Chinese academic, clearly distinguishes between the two, “While China clearly believes that

  13. A voz de São Paulo: Adoniran Barbosa

    Directory of Open Access Journals (Sweden)

    Maria Izilda Santos de Matos

    2009-11-01

    Full Text Available "He is the voice of the city," said Antonio Candido about Adoniran Barbosa. Through a particular forms of expression, the composer in his songs capture the emotional memories of the city of other times, his production can be considered a possible construction of memory, being selective in the choice of different urban territories and of their characters. This article focuses on the artistic career and the musical production of Adoniran Barbosa and privileges the urbans experiences which he sung in the 40’s, 50’s and 60’s, highlighting his forms of expression.

  14. Der Krieg in Tschetschenien : Folgen für Rußland. Fünf Thesen

    OpenAIRE

    Simon, Gerhard

    1995-01-01

    Bislang funktioniert in Rußland kein demokratisches Institutionengefüge. Weder ist das Gewaltmonopol des Staates durchgesetzt, noch existiert ein Grundkonsens darüber, daß Gewalt ohne rechtsstaatliche Sanktion bei der Lösung von Konflikten ausscheidet. Der Tschetschenien-Krieg zeigt, wie tief die Gesellschaft gespalten ist. Die gefährlichste Folge des Kriegs für Rußland ist die Delegitimierung von Person und Amt des Präsidenten. Wieder beginnt eine Auseinandersetzung darüber, wie Rußland regi...

  15. Areeni aasta albumid 2004

    Index Scriptorium Estoniae

    2004-01-01

    Heliplaatidest: Franz Ferdinand "Franz Ferdinand", Toe Tag "Legendaarne", The Libertines "The Libertines ", Morrissey "You Are The Qarry", The Streets "A Grand Don't Come For Free", Kalm "Generalissimus Kalm", Brian Wilson "Smile", Madvillain "Madvillainy", Scissor Sisters "Scissor Sisters", Gary Wilson "Mary Had A Brown Hair", Animal Collective "Sung Tongs", Keane "Hopes And Fears", Todd Rundgren "Liars", Nick Cave & The Bad Seeds "Abbatoir Blues/The Lyre of Orpheus", Mylo "Destroy Rock'n'Roll", Devendra Banhart "Rejoicing In The Hands", Stefani "Love Angel Music Baby", Björk "Medulla", Moodymann "Black Mahogani"

  16. Disease: H00780 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00780 Atrichia with papular lesions Atrichia with papular lesions is a rare diseas...e characterized by early onset irreversible alopecia and papular lesions of keratin-filled cysts over the ex...Yip L, Horev L, Sinclair R, Zlotogorski A Atrichia with papular lesions: a report of three novel human hairl..., Kafaitullah, Kamran-ul-hassan Naqvi S, Ali G, Ahmad W Congenital atrichia with papular lesions resulting f...ang HJ, Park SW, Sung HS Detection of a novel missense mutations in atrichia with papular lesions. Ann Derma

  17. A study of auditory preferences in nonhandicapped infants and infants with Down's syndrome.

    Science.gov (United States)

    Glenn, S M; Cunningham, C C; Joyce, P F

    1981-01-01

    11 infants with Down's syndrome (MA 9.2 months, CA 12.7 months) and 10 of 11 nonhandicapped infants (MA 9.6 months, CA 9.3 months) demonstrated that they could operate an automated device which enabled them to choose to listen to 1 of a pair of auditory signals. All subjects showed preferential responding. Both groups of infants showed a significant preference for nursery rhymes sung by a female voice rather than played on musical instruments. The infants with Down's syndrome had much longer response durations for the more complex auditory stimuli. The apparatus provides a useful technique for studying language development in both normal and abnormal populations.

  18. Analyse Geländemodell für die Erosionsbewertung

    OpenAIRE

    Köthe, Rüdiger; Wurbs, Daniel, 1974-

    2011-01-01

    Bisherige Auswertungen der Erosionsgefährdung stützen sich auf das landesweit verfügbare Digitale Geländemodell (DGM) mit einer Rasterweite von 20 m (DGM20). Das neu erstellte DGM2 bietet durch seine Rasterweite von 2 m erstmalig eine sehr hohe räumliche Auflösung. In Testgebieten wurden die Auswirkungen der neuen Datengrundlage DGM2 (Laserscanbefliegung) auf die Erosionsgefährdungsbewertung analysiert. Verschiedene DGM-Aufbereitungsverfahren sowie DGM-Rasterweiten wurden im Hinblick auf ...

  19. Entwicklung eines Systems für verteiltes, paralleles Echtzeit-Raytracing

    OpenAIRE

    Berthold, Frieder

    2013-01-01

    Das Projekt "`Virtual Reality for On-Orbit Servicing"' hat die Simulation von Wartungsarbeiten an Satelliten im Erdorbit als Ziel. Dafür werden Methoden der Virtuellen Realität eingesetzt. Für die Visualisierung existiert ein Raytracer, der auf einem einzelnen Computer läuft. Dieser erreichte aber nicht die nötigen interaktiven Bildwiederholraten von 30 Bildern pro Sekunde bei HD-Auflösung. Da jedoch solche Bildraten nötig sind, um als Benutzer sinnvoll mit der Simulation interagieren zu k...

  20. A LAMENT OF CYPRUS REGION: “ARAB ALİ” AND VARIATIONS

    Directory of Open Access Journals (Sweden)

    Şevket ÖZNUR

    2011-04-01

    Full Text Available This article is about the research of the lament text lamented for Arap Ali who was killed in 1943 in Famagusta, Cyprus by English soldiers. This lament was sung among people so many times that we encounter (can see its different variations in Kerkük and Anatolia. As a matter of fact the story, the contrastive analyis and similarity and difference of these variants have been evaluated. Besides interpretation, research and evaluation inthe frame of literature and language evaluation, local folkloric characteristics have been tried to make firm.

  1. GENIE TRECVID2011 Multimedia Event Detection: Late Fusion Approaches to Combine Multiple Audio Visual features

    Science.gov (United States)

    2012-03-01

    27, May 2011. [2] Sheng Gao, De- Hong Wang , and Chin-Hui Lee. Automatic image annotation through multi-topic text categorization. In ICASSP, 2006. [3...International Journal of Computer Vision, 42(3):145175, 2001. [9] De- Hong Wang , Sheng Gao, Qi Tian, and Wing-Kin Sung. Discriminative fusion approach for automatic image annotation. In MMSP, 2005. ...Government. References [1] Chih -Chung Chang and Chih -Jen Lin. Libsvm: A library for support vector machines. ACM Trans. Intell. Syst. Technol., 2:27:127

  2. Consumption 3.0: A web-based proposal for supporting social and ecological awareness in private consumption

    Directory of Open Access Journals (Sweden)

    Alexander Petring

    2013-03-01

    Full Text Available Angesichts der zunehmender ökologischer Herausforderungen und sich verschärfender sozialer Problemlagen in vielen Ländern der Welt wurde zuletzt intensiv über Chancen und Risiken der Einbeziehung privater Konsumhandlungen bei der Lösung der Nachhaltigkeitsproblematik diskutiert. Dieser Beitrag knüpft an diese Debatte an und macht einen konkreten Vorschlag, wie das Internet stärker als bisher dazu genutzt werden könnte, sozial-ökologische Kriterien bei Konsumentscheidungen zu stärken.

  3. Qha Ke (Guiding the Way From the Hmong Ntsu of China, 1943

    Directory of Open Access Journals (Sweden)

    Nicholas Tapp

    2009-01-01

    Full Text Available This article provides the text of Ruey Yih-Fu's 1943 collected version of the Qhuab Ke, or Song of Opening the Way, sung at a Hmong funeral in China. An English translation is provided based on the Hmong and Chinese translations given by Ruey, together with extensive notes and details about the Song. Ruey's own IPA-based transliteration is mainly kept, with some modifications in view of RPA. It appears to be one of the earliest and most original versions of the Qhuab Ke we have.

  4. Evaluation of the Applicability of HTML5 for Mobile Applications in Resource-Constrained Edge Environments

    Science.gov (United States)

    2014-07-01

    Google Chrome, Firefox for Android, and Dolphin web browsers, on a Google Nexus 7 tablet and a Sam- sung Galaxy S4 smartphone , running Version 4.3...to PhoneGap, and replace it with the corresponding HTML5 JavaScript code. Although up to 100% of the JavaScript source code of a hybrid mobile app...created using PhoneGap must be replaced , the original HTML web page layout and the CSS files that define the look and feel of the web page can be

  5. Música popular y nacionalismo en los campamentos insurgentes. Cuba (1895-1898

    Directory of Open Access Journals (Sweden)

    Jaddiel Díaz Frene

    2015-09-01

    Full Text Available This article reconstructs the social uses of the décimas (ten-line stanzas sung in the insurgent camps during the war for independence that began in Cuba in 1895. Through a review of personal diaries, newspapers, and photos of the conflict, the article attempts to answer various questions: What emotions did this poetic musical genre produce in the everyday life of the combatants? How did the war affect such cultural practices? Is it possible to find black and mulatto decimistas among the Cuban troops? What role did officers play in these everyday forms of expression about the political life of the country?

  6. Magnetic fields and beam optics studies of a 250 MeV superconducting proton radiotherapy cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong-Won [Research Institute and Hospital, National Cancer Center, 809 Madu-dong, Koyang, Kyonggi (Korea, Republic of)], E-mail: jwkim@ncc.re.kr

    2007-11-21

    A 250 MeV superconducting cyclotron for the proton radiation therapy was designed at the Michigan State University (MSU) for use at the Paul Scherrer Institut. This work was based on the conceptual design carried out at the MSU in 1994. The previous design was refined to finalize the magnet configuration and to optimally arrange cyclotron elements for the actual construction. The spiral angle of the pole was reduced, the new hill-edges and valley shims being introduced. The magnetic fields were highly isochronized using a least square fitting routine involving a schematic shimming scheme. The resulting reference field was adequate for the elaborate study of beam optics. The optics simulation predicted that extraction efficiency of above 80% was achievable for a beam with the initial phase width of 20{sup o}. The vertical deflector was investigated located in the central region to control the beam intensity with tracking of beam phase spaces. Some measurement results for the constructed cyclotron were found in a good agreement with those of the optics study.

  7. Development of radioisotope tracer technology

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Joon Ha; Lee, Myun Joo; Jung, Sung Hee; Park, Soon Chul; Lim, Dong Soon; Kim, Jae Ho; Lee, Jae Choon; Lee, Doo Sung; Cho, Yong Suk; Shin, Sung Kuan

    2000-04-01

    The purpose of this study is to develop the radioisotope tracer technology, which can be used in solving industrial and environmental problems and to build a strong tracer group to support the local industries. In relation to the tracer technology in 1999, experiments to estimate the efficiencies of a sludge digester of a waste water treatment plant and a submerged biological reactor of a dye industry were conducted. As a result, the tracer technology for optimization of facilities related to wastewater treatment has been developed and is believed to contribute to improve their operation efficiency. The quantification of the experimental result was attempted to improve the confidence of tracer technology by ECRIN program which basically uses the MCNP simulation principle. Using thin layer activation technique, wear of tappet shim was estimated. Thin layer surface of a tappet shim was irradiated by proton beam and the correlation between the measured activity loss and the amount of wear was established. The equipment was developed to adjust the energy of proton which collides with the surface of tappet. The tracer project team has participated into the tracer test for estimating the efficiency of RFCC system in SK cooperation. From the experiment the tracer team has obtained the primary elements to be considered for judging the efficiency of RFCC unit. By developing the tracer techniques to test huge industrial units like RFCC, the tracer team will be able to support the local industries that require technical services to solve any urgent trouble. (author)

  8. Influence of social motivation, self-perception of social efficacy and normative adjustment in the peer setting.

    Science.gov (United States)

    Herrera López, Mauricio; Romera Félix, Eva M; Ortega Ruiz, Rosario; Gómez Ortiz, Olga

    2016-01-01

    The first objective of this study was to adapt and test the psychometric properties of the Social Achievement Goal Scale (Ryan & Shim, 2006) in Spanish adolescent students. The second objective sought to analyse the influence of social goals, normative adjustment and self-perception of social efficacy on social adjustment among peers. A total of 492 adolescents (54.1% females) attending secondary school (12-17 years; M = 13.8, SD = 1.16) participated in the study. Confirmatory factor analysis and structural equation modelling were performed. The validation confirmed the three-factor structure of the original scale: social development goals, social demonstration-approach goals and social demonstration-avoidance goals. The structural equation model indicated that social development goals and normative adjustment have a direct bearing on social adjustment, whereas the social demonstration-approach goals (popularity) and self-perception of social efficacy with peers and teachers exert an indirect influence. The Spanish version of the Social Achievement Goal Scale (Ryan & Shim, 2006) yielded optimal psychometric properties. Having a positive motivational pattern, engaging in norm-adjusted behaviours and perceiving social efficacy with peers is essential to improving the quality of interpersonal relationships.

  9. Combination of a multimode antenna and TIAMO for traveling-wave imaging at 9.4 Tesla.

    Science.gov (United States)

    Hoffmann, Jens; Mirkes, Christian; Shajan, G; Scheffler, Klaus; Pohmann, Rolf

    2016-01-01

    To investigate the performance of a multimode antenna combined with time-interleaved acquisition of modes (TIAMO) for improved (1)H image homogeneity as compared to conventional traveling-wave imaging in the human brain at 9.4 Tesla (T). An adjustable three-port antenna was built to stimulate the propagation of three basic waveguide modes within a 9.4 T scanner bore. For TIAMO, two time-interleaved acquisitions using different linear combinations of these modes were optimized to achieve a homogeneous rooted sum-of-squares combination of their B1+ patterns ( B1,RSS+). The antenna's transmit and receive performance, as well as local specific absorption rate, were analyzed using experiments and numerical simulations. The optimized TIAMO B1,RSS+ combination was superior to radiofrequency shimming. Across the entire brain, it improved the homogeneity of the excitation field by a factor of two and its maximum-to-minimum ratio by almost a factor of five as compared to the circularly polarized mode. The two-fold increase in "virtual" receive channels enhanced the parallel imaging performance and enabled the use of higher acceleration factors. Despite the limited number of channels, a remote three-port antenna combined with TIAMO represents an easily implementable setup to achieve void-free (1)H images from the entire brain at 9.4 T, which can be used for anatomical localization and B0 shimming. © 2015 Wiley Periodicals, Inc.

  10. Comparison Between Eight- and Sixteen-Channel TEM Transceive Arrays for Body Imaging at 7 Tesla

    Science.gov (United States)

    Snyder, CJ; DelaBarre, L; Moeller, S; Tian, J; Akgun, C; Van De Moortele, P-F; Bolan, PJ; Ugurbil, K; Vaughan, JT; Metzger, GJ

    2011-01-01

    Eight- and sixteen-channel transceive stripline/TEM body arrays were compared at 7 tesla (297 MHz) both in simulation and experimentally. Despite previous demonstrations of similar arrays for use in body applications, a quantitative comparison of the two configurations has not been undertaken to date. Results were obtained on a male pelvis for assessing transmit, SNR and parallel imaging performance and to evaluate local power deposition versus transmit B1 (B1+). All measurements and simulations were conducted after performing local B1+ phase shimming in the region of the prostate. Despite the additional challenges of decoupling immediately adjacent coils, the sixteen-channel array demonstrated improved or nearly equivalent performance to the eight-channel array based on the evaluation criteria. Experimentally, transmit performance and SNR were 22% higher for the sixteen-channel array while significantly increased reduction factors were achievable in the left-right direction for parallel imaging. Finite-difference time-domain simulations demonstrated similar results with respect to transmit and parallel imaging performance, however a higher transmit efficiency advantage of 33% was predicted. Simulations at both 3T and 7T verified the expected parallel imaging improvements with increasing field strength and showed that, for a specific B1+ shimming strategy employed, the sixteen-channel array exhibited lower local and global SAR for a given B1+. PMID:22102483

  11. Celibato en el Judaísmo Antiguo

    Directory of Open Access Journals (Sweden)

    van der Horst, Pieter W.

    2002-06-01

    Full Text Available Even though the first commandment in the Bible, «Be fruitful and multiply» (Gen. 1:28, countered the development of sexual asceticism in early Judaism, yet there is clear evidence of persons and groups choosing voluntary celibacy as a Jewish way of life. The evidence concerning the Essenes, the Therapeutae, Banus, Shim'on ben Azzai, John the Baptist and Jesus of Nazareth is discussed in this article as are the consequences for the rise of celibacy in early Christianity.

    Aunque el primer mandamiento de la Biblia, «Creced y multiplicaos» (Gen. 1:28, no propiciara el desarrollo del ascetismo sexual en el judaismo antiguo, hay claros testimonios de personas y grupos que eligen el celibato voluntario como una forma de vida judía. En este artículo se examinan las pruebas relativas a los esenios, los Therapeutae, Banus, Shim'on ben Azzai, Juan el Bautista y Jesús de Nazaret, así como sus consecuencias en el desarrollo del celibato en el cristianismo primitivo.

  12. The quantitative ADAM questionnaire: a new tool in quantifying the severity of hypogonadism

    Science.gov (United States)

    Mohamed, O; Freundlich, R E; Dakik, H K; Grober, E D; Najari, B; Lipshultz, L I; Khera, M

    2009-01-01

    Androgen deficiency is a pervasive problem in the older male population and is thought to be responsible for many symptoms once considered to be the result of normal aging. Numerous methods have been proposed to facilitate the detection of men at risk for androgen deficiency. In this article, we propose a novel screening tool, the quantitative Androgen Deficiency in the Aging Male (qADAM) questionnaire and report its successful use in quantifying the severity of androgen deficiency in a group of older men. Fifty-seven males scheduled to undergo radical prostatectomy for prostate cancer completed the qADAM as well as the Sexual Health Inventory for Men (SHIM) and the Expanded Prostate Cancer Index Composite hormonal/sexual (EPICh/EPICs) questionnaires. Thirty-four men also had serum testosterone levels measured for comparison. The qADAM showed statistically significant correlation to the SHIM (P=0.001), EPICh (P=0.016), EPICs (P=<0.001), and serum testosterone (P=0.046). The qADAM represents a viable alternative to existing questionnaires used to detect androgen deficiency and to assess response to treatment. PMID:19657348

  13. RDS-21 Face-Gear Surface Durability Tests

    Science.gov (United States)

    Lewicki, David G.; Heath, Gregory F.; Filler, Robert R.; Slaughter, Stephen C.; Fetty, Jason

    2007-01-01

    Experimental fatigue tests were performed to determine the surface durability life of a face gear in mesh with a tapered spur involute pinion. Twenty-four sets of gears were tested at three load levels: 7200, 8185, and 9075 lb-in face gear torque, and 2190 to 3280 rpm face gear speed. The gears were carburized and ground, shot-peened and vibro-honed, and made from VIM-VAR Pyrowear 53 steel per AMS 6308. The tests produced 17 gear tooth spalling failures and 7 suspensions. For all the failed sets, spalling occurred on at least one tooth of all the pinions. In some cases, the spalling initiated a crack in the pinion teeth which progressed to tooth fracture. Also, spalling occurred on some face gear teeth. The AGMA endurance allowable stress for a tapered spur involute pinion in mesh with a face gear was determined to be 275 ksi for the material tested. For the application of a tapered spur involute pinion in mesh with a face gear, proper face gear shim controlled the desired gear tooth contact pattern while proper pinion shim was an effective way of adjusting backlash without severely affecting the contact pattern.

  14. Do adult men with untreated hypospadias have adverse outcomes? A pilot study using a social media advertised survey.

    Science.gov (United States)

    Schlomer, Bruce; Breyer, Benjamin; Copp, Hillary; Baskin, Laurence; DiSandro, Michael

    2014-08-01

    Hypospadias is usually treated in childhood. Therefore, the natural history of untreated mild hypospadias is unknown. We hypothesized that men with untreated hypospadias, especially mild, do not have adverse outcomes. Facebook was used to advertise an electronic survey to men older than 18 years. Men with untreated hypospadias identified themselves and indicated the severity of hypospadias with a series of questions. Outcomes included: Sexual Health Inventory for Men (SHIM), penile curvature and difficulty with intercourse, International Prostate Symptom Score (IPSS), Penile Perception Score (PPS), psychosexual milestones, paternity, infertility, sitting to urinate, and the CDC HRQOL-4 module. 736 men completed self-anatomy questions and 52 (7.1%) self-identified with untreated hypospadias. Untreated hypospadias participants reported worse SHIM (p < 0.001) and IPSS scores (p = 0.05), more ventral penile curvature (p = 0.003) and resulting difficulty with intercourse (p < 0.001), worse satisfaction with meatus (p = 0.011) and penile curvature (p = 0.048), and more sitting to urinate (p = 0.07). When stratified by mild and severe hypospadias, severe hypospadias was associated with more adverse outcomes than mild hypospadias. Men with untreated hypospadias reported worse outcomes compared with non-hypospadiac men. Mild untreated hypospadias had fewer adverse outcomes than severe hypospadias. Research is needed to determine if treatment of childhood hypospadias improves outcomes in adults, especially for mild hypospadias. Copyright © 2014 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

  15. Portable, Low-cost NMR with Laser-Lathe Lithography Produced

    Energy Technology Data Exchange (ETDEWEB)

    Herberg, J L; Demas, V; Malba, V; Bernhardt, A; Evans, L; Harvey, C; Chinn, S; Maxwell, R; Reimer, J; Pines, A

    2006-12-21

    Nuclear Magnetic Resonance (NMR) is unsurpassed in its ability to non-destructively probe chemical identity. Portable, low-cost NMR sensors would enable on-site identification of potentially hazardous substances, as well as the study of samples in a variety of industrial applications. Recent developments in RF microcoil construction (i.e. coils much smaller than the standard 5 mm NMR RF coils), have dramatically increased NMR sensitivity and decreased the limits-of-detection (LOD). We are using advances in laser pantographic microfabrication techniques, unique to LLNL, to produce RF microcoils for field deployable, high sensitivity NMR-based detectors. This same fabrication technique can be used to produce imaging coils for MRI as well as for standard hardware shimming or 'ex-situ' shimming of field inhomogeneities typically associated with inexpensive magnets. This paper describes a portable NMR system based on a laser-fabricated microcoil and homebuilt probe design. For testing this probe, we used a hand-held 2 kg Halbach magnet that can fit into the palm of a hand, and an RF probe with laser-fabricated microcoils. The focus of the paper is on the evaluation of the microcoils, RF probe, and first generation gradient coils. The setup of this system, initial results, sensitivity measurements, and future plans are discussed. The results, even though preliminary, are promising and provide the foundation for developing a portable, inexpensive NMR system for chemical analysis. Such a system will be ideal for chemical identification of trace substances on site.

  16. Obtained and characterization of composite materials W-Cu for electrical contact; Obtencion y caracterizacion de materiales compuestos W-Cu para contactos electricos

    Energy Technology Data Exchange (ETDEWEB)

    Krivij, N.; Alfonso-Trujillo, E.; Garcia-Sanchez, L. L.; Villalonga, J. A.; Formoso-Prego, A.; Alguacil, E. J.; Corres-Sanchez, A.

    2003-07-01

    In the Cuban Metallurgical Research Center (CIME), are manufactured by powder metallurgy, shims of adjustment of a W-Cu composite material, that are used in the electrical contacts of the panels of control of the portico derricks that operate in the port of Havana City. The base material used has a composition of 70% in mass electrolytic copper powder and wolfram powder of (30%) that is obtained by reduction from the oxide from wolfram. The powders are submitted to the stages of mixed, pressed and agglomeration and is obtained a composite material with free particles of W occluded in a counterfoil of Cu matrix, that do not interact and they provide the following properties: high melting temperature, high electro and thermo conductivity and corrosion resistance, high mechanical and electrical strengtheners, decrease weldability and stability during their development. However, when not reacting the volframio particles with the copper, the compound material will begin to fuse to the temperature of the copper, on the other hand and for the same reason the resistance to the corrosion should be similar to that of the pure copper. The shims of adjustment are fixed to the bodies of high purity copper welding with a silver alloy, the one which provides the maximum qualities of the Cu, as elasticity, breaking strength, thermal and electrical conductivities, as well corrosion resistance. (Author) 36 refs.

  17. The effects of stress on singing voice accuracy.

    Science.gov (United States)

    Larrouy-Maestri, Pauline; Morsomme, Dominique

    2014-01-01

    The quality of a music performance can be lessened or enhanced if the performer experiences stressful conditions. In addition, the quality of a sung performance requires control of the fundamental frequency of the voice, which is particularly sensitive to stress. The present study aimed to clarify the effects of stress on singing voice accuracy. Thirty-one music students were recorded in a stressful condition (ie, a music examination) and a nonstressful condition. Two groups were defined according to the challenge level of the music examination (first and second music levels). Measurements were made by self-reported state anxiety (CSAI-2R questionnaire) and by observing heart rate activity (electrocardiogram) during each performance. In addition, the vocal accuracy of the sung performances was objectively analyzed. As expected, state anxiety and heart rate were significantly higher on the day of the music examination than in the nonstressful condition for all the music students. However, the effect of stress was positive for the first-year students but negative for the second-year students, for whom the music examination was particularly challenging. In addition, highly significant correlations were found between the intensity of cognitive symptoms and the vocal accuracy criteria. This study highlights the contrasting effects of stress on singing voice accuracy but also the need to consider the challenge level and perception of the symptoms in experimental and pedagogical settings. Copyright © 2014 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  18. Perception of words and pitch patterns in song and speech

    Directory of Open Access Journals (Sweden)

    Julia eMerrill

    2012-03-01

    Full Text Available This fMRI study examines shared and distinct cortical areas involved in the auditory perception of song and speech at the level of their underlying constituents: words, pitch and rhythm. Univariate and multivariate analyses were performed on the brain activity patterns of six conditions, arranged in a subtractive hierarchy: sung sentences including words, pitch and rhythm; hummed speech prosody and song melody containing only pitch patterns and rhythm; as well as the pure musical or speech rhythm.Systematic contrasts between these balanced conditions following their hierarchical organization showed a great overlap between song and speech at all levels in the bilateral temporal lobe, but suggested a differential role of the inferior frontal gyrus (IFG and intraparietal sulcus (IPS in processing song and speech. The left IFG was involved in word- and pitch-related processing in speech, the right IFG in processing pitch in song.Furthermore, the IPS showed sensitivity to discrete pitch relations in song as opposed to the gliding pitch in speech. Finally, the superior temporal gyrus and premotor cortex coded for general differences between words and pitch patterns, irrespective of whether they were sung or spoken. Thus, song and speech share many features which are reflected in a fundamental similarity of brain areas involved in their perception. However, fine-grained acoustic differences on word and pitch level are reflected in the activity of IFG and IPS.

  19. The beneficial effects of honeybee-venom serum on facial wrinkles in humans

    Directory of Open Access Journals (Sweden)

    Han SM

    2015-10-01

    Full Text Available Sang Mi Han,1 In Phyo Hong,1 Soon Ok Woo,1 Sung Nam Chun,2 Kwan Kyu Park,3 Young Mee Nicholls,4 Sok Cheon Pak5 1Department of Agricultural Biology, National Academy of Agricultural Science, Wanju, 2Dong Sung Pharmaceuticals Co Ltd, Seoul, 3Department of Pathology, School of Medicine, Catholic University of Daegu, Daegu, South Korea; 4Manuka Doctor Ltd, Auckland, New Zealand; 5School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW, Australia Abstract: Facial wrinkles are an undesirable outcome caused by extrinsic photodamage and intrinsic aging processes. Currently, no effective strategies are known to prevent facial wrinkles. We assessed the beneficial effects of bee-venom serum on the clinical signs of aging skin. Our results show that bee-venom serum treatment clinically improved facial wrinkles by decreasing total wrinkle area, total wrinkle count, and average wrinkle depth. Therefore, bee-venom serum may be effective for the improvement of skin wrinkles. Keywords: bee venom, wrinkle, area, count, depth

  20. Music lessons are associated with increased verbal memory in individuals with Williams syndrome.

    Science.gov (United States)

    Dunning, Brittany A; Martens, Marilee A; Jungers, Melissa K

    2014-11-16

    Williams syndrome (WS) is a genetic disorder characterized by intellectual delay and an affinity for music. It has been previously shown that familiar music can enhance verbal memory in individuals with WS who have had music training. There is also evidence that unfamiliar, or novel, music may also improve cognitive recall. This study was designed to examine if a novel melody could also enhance verbal memory in individuals with WS, and to more fully characterize music training in this population. We presented spoken or sung sentences that described an animal and its group name to 44 individuals with WS, and then tested their immediate and delayed memory using both recall and multiple choice formats. Those with formal music training (average duration of training 4½ years) scored significantly higher on both the spoken and sung recall items, as well as on the spoken multiple choice items, than those with no music training. Music therapy, music enjoyment, age, and Verbal IQ did not impact performance on the memory tasks. These findings provide further evidence that formal music lessons may impact the neurological pathways associated with verbal memory in individuals with WS, consistent with findings in typically developing individuals. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Music as a memory enhancer in patients with Alzheimer's disease.

    Science.gov (United States)

    Simmons-Stern, Nicholas R; Budson, Andrew E; Ally, Brandon A

    2010-08-01

    Musical mnemonics have a long and diverse history of popular use. In addition, music processing in general is often considered spared by the neurodegenerative effects of Alzheimer's disease (AD). Research examining these two phenomena is limited, and no work to our knowledge has explored the effectiveness of musical mnemonics in AD. The present study sought to investigate the effect of music at encoding on the subsequent recognition of associated verbal information. Lyrics of unfamiliar children's songs were presented bimodally at encoding, and visual stimuli were accompanied by either a sung or a spoken recording. Patients with AD demonstrated better recognition accuracy for the sung lyrics than the spoken lyrics, while healthy older adults showed no significant difference between the two conditions. We propose two possible explanations for these findings: first, that the brain areas subserving music processing may be preferentially spared by AD, allowing a more holistic encoding that facilitates recognition, and second, that music heightens arousal in patients with AD, allowing better attention and improved memory. Published by Elsevier Ltd.

  2. TEACHING MATHEMATICS BY LULLABIES IN PRE-SCHOOL PERIOD

    Directory of Open Access Journals (Sweden)

    Gülçin OFLAZ

    2010-04-01

    Full Text Available One of the oral literature products of Turkish culture which is shared from centuries before is called lullaby (Baby songs. Lullabies contain Turkish Nation’s common cultural items that gather us together. Recent researches show that the lullabies which are sung for babies has an educational dimension. With their rich themes lullabies tells about the main problems that the babies and children may confront in their school life and further years. The relation between lullabies and mathematics has been searched at this research. For this purpose the concepts of pre-school education for 3-6 year-old children has been dealt with and a categorising has been made. Then the product called “Turkish Lullabies 1” has been analysed by utilising context analysing of these categorising. According to the findings of the research, the lullabies that have been sung for centuries contain more educational concept than the concepts that are planned to be applied at the pre-school educational programme.

  3. A Brief Chronicle of the Genus Cordyceps Fr., the Oldest Valid Genus in Cordycipitaceae (Hypocreales, Ascomycota)

    Science.gov (United States)

    Tanaka, Eiji; Han, Jae-Gu; Oh, Junsang; Han, Sang-Kuk; Lee, Kang-Hyo

    2014-01-01

    The earliest pre-Linnaean fungal genera are briefly discussed here with special emphasis on the nomenclatural connection with the genus Cordyceps Fr. Since its valid publication under the basidiomycetous genus Clavaria Vaill. ex L. (Clavaria militaris L. Sp. Pl. 2:1182, 1753), the genus Cordyceps has undergone nomenclatural changes in the post-Linnaean era, but has stood firmly for approximately 200 years. Synonyms of Cordyceps were collected from different literature sources and analyzed based on the species they represent. True synonyms of Cordyceps Fr. were defined as genera that represented species of Cordyceps Fr. emend. G. H. Sung, J. M. Sung, Hywel-Jones & Spatafora. The most common synonyms of Cordyceps observed were Clavaria and Sphaeria Hall, reported in the 18th and in the first half of the 19th century, respectively. Cordyceps, the oldest genus in the Cordyceps s. s. clade of Cordycipitaceae, is the most preferred name under the "One Fungus = One Name" principle on priority bases. PMID:25071376

  4. Singing with yourself: evidence for an inverse modeling account of poor-pitch singing.

    Science.gov (United States)

    Pfordresher, Peter Q; Mantell, James T

    2014-05-01

    Singing is a ubiquitous and culturally significant activity that humans engage in from an early age. Nevertheless, some individuals - termed poor-pitch singers - are unable to match target pitches within a musical semitone while singing. In the experiments reported here, we tested whether poor-pitch singing deficits would be reduced when individuals imitate recordings of themselves as opposed to recordings of other individuals. This prediction was based on the hypothesis that poor-pitch singers have not developed an abstract "inverse model" of the auditory-vocal system and instead must rely on sensorimotor associations that they have experienced directly, which is true for sequences an individual has already produced. In three experiments, participants, both accurate and poor-pitch singers, were better able to imitate sung recordings of themselves than sung recordings of other singers. However, this self-advantage was enhanced for poor-pitch singers. These effects were not a byproduct of self-recognition (Experiment 1), vocal timbre (Experiment 2), or the absolute pitch of target recordings (i.e., the advantage remains when recordings are transposed, Experiment 3). Results support the conceptualization of poor-pitch singing as an imitative deficit resulting from a deficient inverse model of the auditory-vocal system with respect to pitch. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. 伊萨:广西融水城卡屯巴哼人民歌演唱场合研究%Yisa:On the Singing Occasions of the Baheng People of Guangxi

    Institute of Scientific and Technical Information of China (English)

    吴宁华; 吴云龙

    2012-01-01

    The Baheng people,one of the many branches of the Yao Ethnic Minority in Guangxi,have their own language,belief and singing culture.Yisa,a name for singing,includes the Yao and Dong songs sung among the Baheng people.The folk songs that were originated from two different ethnic groups,although sung on different occasions and by different contents,both play a role in maintaining the continuity of their culture,ethnicity and family relations.%巴哼人是广西瑶族众多支系中的一支,有着自己独特的语言、信仰和歌唱文化。"伊萨"是巴哼人对"唱歌"的表达,其内涵包括了巴哼瑶歌和侗歌。在生活中,这两种不同语言的民歌被演唱于不同的场合,其内容也有所区别。但是它们在巴哼族群的文化体系中却共同承担着文化、族群和家庭延续的作用。

  6. Correlation ECE diagnostic in Alcator C-Mod

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    Sung C.

    2015-01-01

    electron temperature, Te, fluctuations through standard cross-correlation analysis methods. In Alcator C-Mod, a new CECE diagnostic has been installed[Sung RSI 2012], and interesting phenomena have been observed in various plasma conditions. We find that local Te fluctuations near the edge (ρ ~ 0:8 decrease across the linearto- saturated ohmic confinement transition, with fluctuations decreasing with increasing plasma density[Sung NF 2013], which occurs simultaneously with rotation reversals[Rice NF 2011]. Te fluctuations are also reduced across core rotation reversals with an increase of plasma density in RF heated L-mode plasmas, which implies that the same physics related to the reduction of Te fluctuations may be applied to both ohmic and RF heated L-mode plasmas. In I-mode plasmas, we observe the reduction of core Te fluctuations, which indicates changes of turbulence occur not only in the pedestal region but also in the core across the L/I transition[White NF 2014]. The present CECE diagnostic system in C-Mod and these experimental results are described in this paper.

  7. An Introduction to Amdo Tibetan Love Songs or La Gzhas

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    Skal bzang norbu

    2015-07-01

    Full Text Available Skal bzang norbu. 2015. An Introduction to Amdo Tibetan Love Songs or La Gzhas in Gerald Roche, Keith Dede, Fernanda Pirie, and Benedict Copps (eds Asian Highlands Perspectives 37 Centering the Local, A Festschrift for Dr. Charles Kevin Stuart on the Occasion of his Sixtieth Birthday, 1-36. La gzhas, or Amdo Tibetan love songs, are sung between young men and women to express their love to each other. Several terms are available for this type of love song in Amdo Tibetan. La gzhas is the most common term for such songs in written Tibetan, la meaning 'mountain pass' and gzhas 'song'. In oral Amdo Tibetan, it is la-ye, a homophone of the literary term. Ri glu literally means mountain song, and this term matches the Chinese term for love songs, shan'ge. These two terms indicate where this song is often sung, in the mountains, far away from houses, villages and tents, in places where there are few people around. Rogs 'then has a more romantic connotation, rogs meaning friend or lover, and 'then meaning to pull, or hookup. The lyrics of la gzhas express feelings between men and women. Typically, love songs can be divided into several categories, resembling the progress of love between a young man and woman (Mtsho sngon zhing chen mang tshogs sgyu rtsal khang 1981.

  8. Baltimaade üldlaulupidude laulutraditsioonid ja pärand

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    Guntis Šmidchens

    2016-04-01

    Full Text Available An overview of all the 1,973 songs that have appeared in seventy Estonian, Latvian, and Lithuanian national song celebration programmes from 1869 to the present day reveals a richly innovative, creative tradition: in each of the three festival repertoires, 74–84 percent of the songs were performed only once over the entire history of the national celebrations. When concert participants choose to repeat songs sung in previous years, they identify these songs as heritage. Sometimes, most notably in the retrospective Estonian programmes of 1969 and 2014, a large portion of the concert repertoire was repeated from the past. The tradition as a whole, however, is not necessarily past-oriented. Some celebrations have turned away from heritage. In the 1928 Estonian celebration, for example, only 2 percent of the programme (only one song had ever been sung in an earlier celebration. This, too, is a heritage of song celebrations: future organisers are free to decide how many, if any, songs they wish to repeat from earlier festivals. The song festival tradition allows both innovative and conservative choice of repertoire at any given festival.

  9. Dynamic scattering of electron vortex beams--a Bloch wave analysis.

    Science.gov (United States)

    Mendis, B G

    2015-02-01

    Two important applications of electron vortex beams are in electron magnetic chiral dichroism (EMCD) measurements and nanoparticle manipulation. In both cases orbital angular momentum (〈Lz〉) transfer between the vortex beam and the specimen due to dynamic scattering is critical. In general the 〈Lz〉 pendellösung consists of short and long wavelength oscillations. The former is due to interference between the tightly bound 1s and more dispersive non-1s Bloch states, while the latter is due to interference between the non-1s states. For EMCD experiments with ±ħ angular momentum beams, momentum transfer can be minimised by selecting the appropriate aperture size, so that the probe wavefunction approximately matches that of the 2p-type Bloch states. For manipulating nanoparticles with large angular momentum beams small apertures are required to excite the 1s state and thereby enhance the short wavelength oscillations in 〈Lz〉. This enables efficient momentum transfer to the specimen, provided the nanoparticle dimension corresponds to a minimum in the 〈Lz〉 pendellösung.

  10. 两两NQD列的Marcinkiewicz-Zygmund不等式及其应用%MARCINKIEWICZ-ZYGMUND INEQUALITY FOR PAIRWISE NQD RANDOM VARIABLES AND ITS APPLICATIONS

    Institute of Scientific and Technical Information of China (English)

    吴永锋

    2015-01-01

    本文研究了两两NQD随机变量的Marcinkiewicz-Zygmund不等式及其应用的问题。利用截尾的方法,获得了两两NQD随机变量的p阶(1≤p<2)Marcinkiewicz-Zygmund不等式结果。作为应用,获得了两两NQD随机变量的两个Lr收敛性结果的简单证明,改进了陈平炎[10]和Sung [20]的相应工作。%In this paper, the author studies the Marcinkiewicz-Zygmund inequality for pair-wise negative quadrant dependent (NQD) random variables and it applications. By using the truncated method, the author obtains the Marcinkiewicz-Zygmund inequality with exponent p (1≤p<2) for pairwise NQD random variables. As applications, the author obtains the simpler proofs of two Lr convergence results for pairwise NQD random variables, which improve the corre-sponding work by Chen [10] and Sung [20] respectively.

  11. [Enamel fluoride uptake following fluoride application and fluoride precipitation].

    Science.gov (United States)

    Buchalla, Wolfgang; Lennon, Aine M; Trage, Katrin; Becker, Klaus; Attin, Thomas

    2007-01-01

    This study is on fluoride uptake into enamel following fluoride precipitation with calcium hydroxide. Five specimens each from 12 bovine incisors were polished, covered with a salivary pellicle, and distributed into five groups (n=12). A fluoride solution (43,500 ppm F from magnesiumfluorosilicate, copper-(II)-fluorosilicate and sodium-fluoride, pH 2; Tiefenfluorid Touchierlösung, Humanchemie) and Ca(OH)2-solution (Tiefenfluorid Nachtouchierlösung) were applied subsequently in group TN. "Touchierlosung" only was used in group T, sodium-fluoride (43,500 ppm F, pH 2) in group NaF, and aminefluoride (Elmex fluid, 10,000 ppm F, pH 4) in group EF. No fluoride was used in group NK (negative control). Following rinsing and 24 h storage in artificial saliva surface KOH-soluble fluoride content (KOHF), and structurally bound fluoride content (SBF) from three layers (0-33, 33-66 and 66-99 pm) was determined by fluoride electrode procedures. KOHF (median in microg/cm2) of NK was below the lower limit of quantification of the fluoride electrode. The other group values were significantly higher (Mann-Whitney test, p precipitation reaction with Ca(OH)2 following fluoridation did not increase enamel fluoride uptake.

  12. Music as a Memory Enhancer in Patients with Alzheimer’s Disease

    Science.gov (United States)

    Simmons-Stern, Nicholas R.; Budson, Andrew E.; Ally, Brandon A.

    2010-01-01

    Musical mnemonics have a long and diverse history of popular use. In addition, music processing in general is often considered spared by the neurodegenerative effects of Alzheimer’s disease (AD). Research examining these two phenomena is limited, and no work to our knowledge has explored the effectiveness of musical mnemonics in AD. The present study sought to investigate the effect of music at encoding on the subsequent recognition of associated verbal information. Lyrics of unfamiliar children’s songs were presented bimodally at encoding, as visual stimuli accompanied by either a sung or a spoken recording. Patients with AD demonstrated better recognition accuracy for the sung lyrics than the spoken lyrics, while healthy older adults showed no significant difference between the two conditions. We propose two possible explanations for these findings: first, that the brain areas subserving music processing may be preferentially spared by AD, allowing a more holistic encoding that facilitates recognition, and second, that music heightens arousal in patients with AD, allowing better attention and improved memory. PMID:20452365

  13. Co-authorship patterns and networks of Korean radiation oncologists.

    Science.gov (United States)

    Choi, Jinhyun; Kang, Jin Oh; Park, Seo Hyun; Kim, Sang Ki

    2011-09-01

    . Among the analysis, a significant difference in the average number of author per article was indicated. The out-degree centrality of network among authors was 4.26% (2.03.7.09%) while in-degree centrality was 1.31% (0.53.2.84%). The three significant nodes were classified and listed as following: Choi, Eun Kyung for 1991-1995, Kim, Dae Young for 1998-2001, Park, Won and Lee, Sang Wook for 2003-2010. Choi, Eun Kyung and Kim, Dae Young appeared in two cases, and ranked as the highest degree in centrality. In the key player analysis, Choi, Eun Kyung and Lee, Sang Wook appeared in two cases, and ranked as the highest. From the cluster analysis, Sungkyunkwan University, Seoul National University and Yonsei University revealed as the three large clusters when Ulsan University, Chonnam National University, and Korea Institute of Radiological & Medical Science as the medium clusters. The Korean radiation oncologist's society shows a closed network with numerous relationships among the particular clusters, and the result indicates it is different from other institutions in the pattern of co-authorship formation of the major hospitals.

  14. Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation

    Directory of Open Access Journals (Sweden)

    Al-Amin M

    2016-12-01

    Full Text Available Md Al-Amin, Jiafu Cao, Muhammad Naeem, Hasanul Banna, Min-Soo Kim, Yunjin Jung, Hae Young Chung, Hyung Ryong Moon, Jin-Wook Yoo College of Pharmacy, Pusan National University, Busan, South Korea Abstract: Hyperpigmentation caused by melanin overproduction is a major skin disorder in humans. Inhibition of tyrosinase, a key regulator of melanin production, has been used as an effective strategy to treat hyperpigmentation. In this study, we investigated the use of solid lipid nanoparticles (SLNs as a highly effective and nontoxic means to deliver a newly synthesized potent tyrosinase inhibitor, MHY498, and to target melanocytes through the skin. MHY498-loaded SLNs (MHY-SLNs were prepared by an oil-in-water emulsion solvent-evaporation method, and their morphological and physicochemical properties were characterized. MHY-SLNs showed a prolonged drug-release profile and higher skin permeation than that of MHY solution. In an in vivo evaluation of antimelanogenic activity, MHY-SLNs showed a prominent inhibitory effect against ultraviolet B-induced melanogenesis, resulting in no change in the skin color of C57BL/6 mouse, compared with that observed in an MHY solution-treated group and an untreated control group. The antimelanogenic effect of MHY-SLNs was further confirmed through Fontana–Masson staining. Importantly, MHY-SLNs did not induce any toxic effects in the L929 cell line. Overall, these data indicate that MHY-SLNs show promise in the topical treatment of hyperpigmentation. Keywords: melanogenesis, hyperpigmentation, MHY498, solid lipid nanoparticles, skin delivery

  15. Bioequivalence evaluation of two amlodipine salts, besylate and orotate, each in a fixed-dose combination with olmesartan in healthy subjects

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    Lee SY

    2015-06-01

    Full Text Available Soo-Yun Lee,1 Jung-Ryul Kim,2,3 Jin Ah Jung,4 Wooseong Huh,2,5 Mi Young Bahng,6 Jae-Wook Ko1,2 1Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea; 2Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Seoul, Republic of Korea; 3Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea; 4Department of Clinical Pharmacology, Inje University, Busan Paik Hospital, Busan, Republic of Korea; 5Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 6Dong-A ST Co., Ltd., Seoul, Republic of Korea Abstract: A fixed-dose combination of amlodipine and olmesartan is used to treat high blood pressure in patients whose hypertension is not sufficiently controlled with either drug alone. The objective of this study was to evaluate the bioequivalence of two fixed-dose combinations, ie, amlodipine orotate/olmesartan medoxomil 10/40 mg and amlodipine besylate/olmesartan medoxomil 10/40 mg, in healthy subjects. A randomized, open-label, single-dose, two-sequence, two-period, crossover study was conducted in 30 healthy adult volunteers. Blood samples were collected for up to 72 hours post-dose in each period. Safety data included the results of physical examinations, clinical laboratory tests, vital signs, an electrocardiogram, and adverse events. For both amlodipine and olmesartan, the 90% confidence intervals for the geometric mean ratios of AUClast and time to peak plasma concentration fell within the bioequivalence acceptance criteria. The two fixed-dose combinations showed similar safety profiles. Amlodipine orotate/olmesartan medoxomil 10/40 mg was bioequivalent to amlodipine besylate/olmesartan medoxomil 10/40 mg. Keywords: amlodipine orotate, amlodipine besylate, olmesartan medoxomil, fixed-dose combination, bioequivalence

  16. Celecoxib coupled to dextran via a glutamic acid linker yields a polymeric prodrug suitable for colonic delivery

    Directory of Open Access Journals (Sweden)

    Lee Y

    2015-07-01

    Full Text Available Yonghyun Lee,1,2,* Jungyun Kim,1,* Wooseong Kim,1,* Joon Nam,1,* Seongkeun Jeong,1 Sunyoung Lee,1 Jin-Wook Yoo,1 Min-Soo Kim,1 Yunjin Jung1 1College of Pharmacy, Pusan National University, Busan, 2Bio-Nanomedicine Laboratory, Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea *These authors contributed equally to this work Abstract: Celecoxib, a selective cyclooxygenase-2 inhibitor, is potentially useful for the treatment of colonic diseases such as colorectal cancer and colitis. However, the cardiovascular toxicity of celecoxib limits its routine use in the clinic. Generally, colon-specific delivery of a drug both increases the therapeutic availability in the large intestine and decreases the systemic absorption of the drug, most likely resulting in enhanced therapeutic effects against colonic diseases such as colitis and reduced systemic side effects. To develop a colon-specific prodrug of celecoxib that could reduce its cardiovascular toxicity and improve its therapeutic activity, dextran–glutamic acid–celecoxib conjugate (glutam-1-yl celecoxib-dextran ester [G1CD] was prepared and evaluated. While stable in pH 1.2 and 6.8 buffer solutions and small-intestinal contents, G1CD efficiently released celecoxib in cecal contents. Oral administration of G1CD to rats delivered a larger amount of celecoxib to the large intestine than free celecoxib. G1CD prevented the systemic absorption of celecoxib and did not decrease the serum level of 6-ketoprostaglandin F1α, an inverse indicator of cardiovascular toxicity of celecoxib. Collectively, G1CD may be a polymeric colon-specific celecoxib prodrug with therapeutic and toxicological advantages. Keywords: colon-specific drug delivery, dextran, celecoxib, prodrug, cardiovascular toxicity

  17. ORNAMENTAL SPECIES USED IN WATER GARDENS FROM SOUTH KOREA

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    PARK SANG KUN

    2009-12-01

    Full Text Available Aquatic plants (hydrophytic plants or hydrophytes are plants that have adapted to live in or on aquatic environments. Because they are living under the water require numerous special adaptations, aquatic plants can only grow in water or permanently saturated soil. Aquatic vascular plants can be ferns or angiosperms (from a variety of families, including monocots and dicots. As opposed to plants types such as mesophytes and xerophytes, hydrophytes do not have a problem in retaining water due to the abundance of water in its environment. This means the plant has less need to regulate transpiration (indeed, the regulation of transpiration would require more energy than the possible benefits incurred.The Korean vascular flora contains 217 families, 1.045 genera, 3.034 species, and 406 infraspecific taxa [CHONG-WOOK PARK, 2007].In Mokp’o region (South Korea, in 1995, was identified hydrophytes species composed by 11 orders, 22 families, 23 genera, 38 species, 9 varieties, total 48 taxa. These were composed by 22 taxa emerged plants, 15 taxa floating-leaves plants, 8 taxa submerged plants and 3 taxa free-floating plants [JEONG WOO-GYU & al., 1995].The same research collective, in 1996, in Paksil, Yundang (South Korea swamp region was identified hydrophytes species composed by 11 orders, 22 families, 31 genera, 41 species, 10 varieties; it represents 12.1% of total plants. These is composed of 25 taxa emerged plants, 15 taxa floating-leaves plants, 9 taxa submerged plants and 3 taxa free-floating plants [JEONG WOO-GYU & al., 1996].This paper contains the classification of water plants and a brief description of some aquatic species used in Korean ancient and modern gardens in order to introduce in our country.

  18. Pharmacogenetic analysis of cinacalcet response in secondary hyperparathyroidism patients

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    Jeong S

    2016-07-01

    Full Text Available Sohyun Jeong,1 In-Wha Kim,1 Kook-Hwan Oh,2 Nayoung Han,1 Kwon Wook Joo,2 Hyo Jin Kim,2 Jung Mi Oh1 1College of Pharmacy, Research Institute of Pharmaceutical Sciences, Seoul National University, 2Department of Internal Medicine, Division of Nephrology, Seoul National University Hospital, Seoul, Korea Background: Secondary hyperparathyroidism (SHPT is one of the major risk factors of morbidity and mortality in end-stage renal disease. Cinacalcet effectively controls SHPT without causing hypercalcemia and hyperphosphatemia. However, there is significant inter-individual response variance to cinacalcet treatment. Therefore, we aimed to evaluate the genetic effects related with parathyroid hormone regulation as factors for cinacalcet response variance. Methods: Patients with a diagnosis of SHPT based on intact parathyroid hormone (iPTH >300 pg/mL on dialysis were included in this study. They were over 18 years and have been treated by cinacalcet for more than 3 months. Responders and nonresponders were grouped by the serum iPTH changes. Twenty-four single nucleotide polymorphisms of CASR, VDR, FGFR1, KL, ALPL, RGS14, NR4A2, and PTHLH genes were selected for the pharmacogenetic analysis. Results: After adjusting for age, sex, and calcium level, CASR rs1042636 (odds ratio [OR]: 0.066, P=0.027 and rs1802757 (OR: 10.532, P=0.042 were associated with cinacalcet response. The association of haplotypes of CASR rs1042636, rs10190, and rs1802757; GCC (OR: 0.355, P=0.015; and ATT (OR: 2.769, P=0.014 with cinacalcet response was also significant. Conclusion: We obtained supporting information of the associations between cinacalcet response and CASR polymorphisms. CASR single nucleotide polymorphisms (SNPs rs1802757, rs1042636, and haplotypes of rs1042636, rs10190, and rs1802757 were significantly associated with cinacalcet response variance. Keywords: CASR, calcium sensing receptor, SHPT, genetic polymorphisms, haplotype, single nucleotide polymorphisms

  19. 5-aminolevulinic acid-incorporated poly(vinyl alcohol nanofiber-coated metal stent for application in photodynamic therapy

    Directory of Open Access Journals (Sweden)

    Kang DH

    2012-05-01

    Full Text Available Jin Ju Yoo*, Chan Kim*, Chung-Wook Chung, Young-Il Jeong, Dae Hwan KangNational Research and Development Center for Hepatibiliary Disease, Pusan National University Yangsan Hospital, Gyeongnam 626-770, Korea *These authors contributed equally to this work.Background: The study investigated the use of combined photodynamic therapy (PDT and stent placement for the treatment of cholangiocarcinoma (CC. For this purpose, 5-aminolevulinic acid (ALA was incorporated into poly(vinyl alcohol (PVA nanofiber, and coated onto metal stents. Their efficacy was assessed in PDT towards HuCC-T1 CC cells.Methods: Fabrication of ALA-PVA nanofiber, and simultaneous coating onto metal stents, was performed through electrospinning. The dark-toxicity, generation of protoporphyrin IX (PpIX, and PDT effect of ALA and ALA-PVA nanofiber were studied in vitro, using HuCC-T1 CC cells.Results: The ALA-PVA nanofibers were coated onto metal stents less than 1000 nm in diameter. ALA-only displayed marginal cytotoxicity; ALA-PVA nanofiber showed less cytotoxicity. PpIX generation was not sigficantly different between ALA and ALA-PVA nanofiber treatments. PVA itself did not generate PpIX in tumor cells. ALA and ALA-PVA nanofiber displayed a similar PDT effect on tumor cells. Cell viability was decreased, dose-dependently, until ALA concentration reached 100 µg/mL. Necrosis and apoptosis of tumor cells occurred similarly for ALA and ALA- PVA nanofiber treatments.Conclusion: The ALA-PVA nanofiber-coated stent is a promising candidate for therapeutic use with cholangiocarcinoma.Keywords: nanofiber, photodynamic therapy, 5-aminolevulinic acid, poly(vinyl alcohol

  20. Novel phytoceramides containing fatty acids of diverse chain lengths are better than a single C18-ceramide N-stearoyl phytosphingosine to improve the physiological properties of human stratum corneum

    Directory of Open Access Journals (Sweden)

    Oh MJ

    2017-09-01

    Full Text Available Myoung Jin Oh,1 Young Hoon Cho,1 So Yoon Cha,1 Eun Ok Lee,2 Jin Wook Kim,2 Sun Ki Kim,2 Chang Seo Park1 1Department of Chemical and Biochemical Engineering, Dongguk University, Chung-gu, Seoul, 2LCS Biotech, Gwonseon-gu, Suwon-si, Gyeonggi-do, Republic of Korea Abstract: Ceramides in the human stratum corneum (SC are a mixture of diverse N-acylated fatty acids (FAs with different chain lengths. C24 is the major class of FAs of ceramides. However, there are also other classes of ceramides with diverse chain lengths of FAs, and these lengths generally range from C16 to C26. This study aimed to prepare several types of phytoceramide containing diverse chain lengths of N-acylated FAs and compare them with C18-ceramide N-stearoyl phytosphingosine (NP in terms of their effects on the physiological properties of the SC. We chose natural oils, such as horse fat oil, shea butter, sunflower oil, and a mixture of macadamia nut, shea butter, moringa, and meadowfoam seed oil, as sources of FAs and phytosphingosine as a sphingoid backbone to synthesize diverse phytoceramides. Each phytoceramide exhibited a distinctive formation of the lamellar structure, and their FA profiles were similar to those of their respective natural oil. The skin barrier properties, as analyzed in human skin, clearly demonstrated that all the phytoceramides improved the recovery rate of the damaged SC and enhanced hydration better than C18-ceramide NP did. In conclusion, natural oil-derived phytoceramides could represent a novel class of ceramides for cosmetic applications in the development of an ideal skin barrier moisturizer. Keywords: fatty acid, chain length, phytoceramide, skin barrier, natural oil

  1. Nitric oxide-releasing poly(lactic-co-glycolic acid-polyethylenimine nanoparticles for prolonged nitric oxide release, antibacterial efficacy, and in vivo wound healing activity

    Directory of Open Access Journals (Sweden)

    Nurhasni H

    2015-04-01

    Full Text Available Hasan Nurhasni,1 Jiafu Cao,1 Moonjeong Choi,1 Il Kim,2 Bok Luel Lee,1 Yunjin Jung,1 Jin-Wook Yoo11College of Pharmacy, Pusan National University, Busan, South Korea; 2Department of Polymer Science and Engineering, Pusan National University, Busan, South KoreaAbstract: Nitric oxide (NO-releasing nanoparticles (NPs have emerged as a wound healing enhancer and a novel antibacterial agent that can circumvent antibiotic resistance. However, the NO release from NPs over extended periods of time is still inadequate for clinical application. In this study, we developed NO-releasing poly(lactic-co-glycolic acid-polyethylenimine (PEI NPs (NO/PPNPs composed of poly(lactic-co-glycolic acid and PEI/diazeniumdiolate (PEI/NONOate for prolonged NO release, antibacterial efficacy, and wound healing activity. Successful preparation of PEI/NONOate was confirmed by proton nuclear magnetic resonance, Fourier transform infrared spectroscopy, and ultraviolet/visible spectrophotometry. NO/PPNPs were characterized by particle size, surface charge, and NO loading. The NO/PPNPs showed a prolonged NO release profile over 6 days without any burst release. The NO/PPNPs exhibited potent bactericidal efficacy against methicillin-resistant Staphylococcus aureus (MRSA and Pseudomonas aeruginosa concentration-dependently and showed the ability to bind on the surface of the bacteria. We also found that the NO released from the NO/PPNPs mediates bactericidal efficacy and is not toxic to healthy fibroblast cells. Furthermore, NO/PPNPs accelerated wound healing and epithelialization in a mouse model of a MRSA-infected wound. Therefore, our results suggest that the NO/PPNPs presented in this study could be a suitable approach for treating wounds and various skin infections.Keywords: nitric oxide-releasing nanoparticles, PLGA, PEI, antimicrobial, wound healing

  2. Exploring Colonial Modernity through the Dynamics of Multilayered Time and Space

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    Yong-ki Lee

    2016-03-01

    Full Text Available Itagaki Ryūta 板垣竜太. Hanguk kŭndae ŭi yŏksa minjokji: Kyŏngbuk sangju ŭi singminji kyŏnghŏm 한국 근대의 역사민족지: 경북 상주의 식민지 경험 [A historical ethnography of Korean modernity: Colonial experience in Sangju, Kyŏngbuk Province]. Translated by Hong Jong-Wook and Yi Taehwa. Seoul: Hyean, 2015. ISBN: 9788984945234. In general, colonial modernity theory considers modernity to be something that was formed after the “Western impact.” Therefore, it has a strong tendency to conceive of the modern and the premodern (chŏnkŭndae as a rupture. Thus, it is unable to understand the “premodern experience” in connection with the historical processes that unfolded after the modern period. Furthermore, colonial modernity theory underscores the image of modernity or the nation-state as a powerful predator that subsumes and claims everything premodern into its territory. Even in its criticism of modernity, then, it falls into a kind of modern-centrism that, although unintentional, privileges modernity’s power over the premodern (Miyazima and Bae 2015. I believe that, more than anything else, in order for colonial modernity theory to mature, it must overcome these limitations. From this perspective, the book by Ryuta Itagaki reviewed here holds great significance for the current paradigm of Korean modern historical studies.

  3. Structural optimization of an asymmetric automotive brake disc with cooling channels to avoid squeal

    Science.gov (United States)

    Wagner, Andreas; Spelsberg-Korspeter, Gottfried; Hagedorn, Peter

    2014-03-01

    Brake squeal is still a major issue in the automotive industry due to comfort complaints of passengers and resulting high warranty costs. Many measures to avoid squeal have been discussed in the engineering community reaching from purely passive measures like the increase of damping, e.g. by the application of shims, to the active or semiactive suppression of squeal. While active measures can be effective but are elaborate and therefore more expensive, passive measure are less complex in most cases. This leads to the necessity to develop passive, economic and robust measures to avoid squeal. Asymmetry of the brake rotor has been proposed to achieve this goal and the resulting split of all double eigenfrequencies of the brake rotor has lately been shown to stabilize the system.

  4. Hybrid high gradient permanent magnet quadrupole

    Science.gov (United States)

    N'gotta, P.; Le Bec, G.; Chavanne, J.

    2016-12-01

    This paper presents an innovative compact permanent magnet quadrupole with a strong gradient for potential use in future light source lattices. Its magnetic structure includes simple mechanical parts, rectangular permanent magnet blocks and soft iron poles. It has a wide aperture in the horizontal plane to accommodate an x-ray beam port, a common constraint in storage ring-based light sources. This specificity introduces field quality deterioration because of the resulting truncation of the poles; a suitable field quality can be restored with an optimized pole shape. A 82 T /m prototype with a bore radius of 12 mm and a 10 mm vertical gap between poles has been constructed and magnetically characterized. Gradient inhomogeneities better than 10-3 in the good field region were obtained after the installation of special shims.

  5. Ageing management and refurbishment of Ghana Research Reactor-1 (GHARR-1)

    Energy Technology Data Exchange (ETDEWEB)

    Amponsahabu, Edward Oscar; Gbadago, Joseph Korbla; Addo, Moses Ankamah; Sogbadji, Robert Bright Mawuko; Odoi, Henry Cecil; Gyamfi, Kwame; Ampong, Atta Gyekye; Opate, Nicholas Sackitey [Ghana Atomic Energy Commission, Accra (Ghana)

    2013-07-01

    Ageing management is an essential component of the routine practices at the Ghana Research Reactor-1 (GHARR-1) Facility. The reactor is Miniature Neutron Source Reactor with a rated power of 30 kW. GHARR-1 was installed and attained criticality on December 17, 1994 and commissioned on 8th March, 1995. It has since been in operation. The routine practices and operational procedures have been set out with clear emphasis on ageing policy at the facility. Some electronic components are changed regularly during maintenance sessions and keeping to regular purification of the reactor and pool water to mitigate against corrosion. This paper outlines the ageing management programme, mitigation practices, strategies for ageing management, periodic safety reviews, consideration of ageing during designing, design features for components and unit replacement, top beryllium shim addition, and succession planning. Information sharing with other operating organization is one of the means considered by GHARR-1 to attain excellence.

  6. Soft calender; Soft calender

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-04-20

    This facility is a soft nip calender with both hot roll and soft roll. Since a multi-zone controlled shim CD roll is used as the soft roll, profile control of a caliper is possible only by deflection control of the roll without any peripheral facility. Main specifications: (1) Kinds of paper: newspaper paper, medium-quality paper, (2) Designed processing speed: 1,100m/min, (3) Paper width: 8,300mm. Features: (1) Possible of keeping paper strength by soft nip, (2) Soft paper surface, high smoothness and excellent gloss by using the hot roll, (3) Uniform ink absorbing by a constant paper bulk density, (4) Large mass even in kinds of paper including much DIP by possible low-linear pressure operation. (translated by NEDO)

  7. Vertically polarizing undulator with dynamic compensation of magnetic forces

    Science.gov (United States)

    Strelnikov, N.; Vasserman, I.; Xu, J.; Jensen, D.; Schmidt, O.; Trakhtenberg, E.; Suthar, K.; Moog, E. R.; Pile, G.; Gluskin, E.

    2017-01-01

    As part of the R&D program of the LCLS-II project, a novel 3.4-meter-long undulator prototype with horizontal magnetic field and dynamic force compensation has recently been developed at the Advanced Photon Source (APS). Previous steps in this development were the shorter 0.8-meter-long and 2.8-meter-long prototypes. Extensive mechanical and magnetic testing were carried out for each prototype, and each prototype was magnetically tuned using magnetic shims. The resulting performance of the 3.4-meter-long undulator prototype meets all requirements for the LCLS-II insertion device, including limits on the field integrals, phase errors, higher-order magnetic moments, and electron-beam trajectory for all operational gaps, as well as the reproducibility and accuracy of the gap settings.

  8. Algorithms for biomagnetic source imaging with prior anatomical and physiological information

    Energy Technology Data Exchange (ETDEWEB)

    Hughett, Paul William [Univ. of California, Berkeley, CA (United States). Dept. of Electrical Engineering and Computer Sciences

    1995-12-01

    This dissertation derives a new method for estimating current source amplitudes in the brain and heart from external magnetic field measurements and prior knowledge about the probable source positions and amplitudes. The minimum mean square error estimator for the linear inverse problem with statistical prior information was derived and is called the optimal constrained linear inverse method (OCLIM). OCLIM includes as special cases the Shim-Cho weighted pseudoinverse and Wiener estimators but allows more general priors and thus reduces the reconstruction error. Efficient algorithms were developed to compute the OCLIM estimate for instantaneous or time series data. The method was tested in a simulated neuromagnetic imaging problem with five simultaneously active sources on a grid of 387 possible source locations; all five sources were resolved, even though the true sources were not exactly at the modeled source positions and the true source statistics differed from the assumed statistics.

  9. Nanostructured polymer- and metal surfaces

    DEFF Research Database (Denmark)

    Christiansen, Alexander Bruun

    , on wafer scale. The BSi structures were replicated into the UV curable organicinorganic hybrid polymer Ormocomp, in order to further assess the optical properties of the structures. BSi structures with lateral dimensions of around 1 μm would selectively scatter specific bands of wavelengths, resulting...... in a structural colour filter for specularly transmitted light. By reducing the height and lateral size, the structures enter a regime where scattering of visible light becomes insignificant. In this regime, the BSi structures were shown to be antireflective. An empirical relation between the characteristic...... moulding in polypropylene. A Ni shim was electroplated from a BSi master, and inserted in an injection moulding tool. The reflectance of the injection moulded parts was reduced from 4.5 % to 2.5% in the visible spectrum. The reflectance was calculated from the gradient in the refractive index from AFM data...

  10. Data of methylome and transcriptome derived from human dilated cardiomyopathy

    Directory of Open Access Journals (Sweden)

    Bong-Seok Jo

    2016-12-01

    Full Text Available Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM. Differentially methylated probes (DMPs and differentially expressed genes (DEGs were identified between the left ventricle (LV, a pathological locus for DCM and the right ventricle (RV, a proxy for normal hearts. The data in this DiB are for supporting our report entitled “Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy” (Bong-Seok Jo, In-Uk Koh, Jae-Bum Bae, Ho-Yeong Yu, Eun-Seok Jeon, Hae-Young Lee, Jae-Joong Kim, Murim Choi, Sun Shim Choi, 2016 [1].

  11. A study of J-coupling spectroscopy using the Earth's field nuclear magnetic resonance inside a laboratory.

    Science.gov (United States)

    Liao, Shu-Hsien; Chen, Ming-Jye; Yang, Hong-Chang; Lee, Shin-Yi; Chen, Hsin-Hsien; Horng, Herng-Er; Yang, Shieh-Yueh

    2010-10-01

    In this paper, an instrumentation of the Earth's field nuclear magnetic resonance (EFNMR) inside a laboratory is presented. A lock-in analysis (LIA) technique was proposed to enhance the signal-to-noise ratio (SNR). A SNR of 137.8 was achieved in a single measurement for 9 ml tap water, and the LIA technique significantly enhanced the SNR to 188 after a 10-average in a noisy laboratory environment. The proton-phosphorus coupling in trimethyl phosphate ((CH(3)O)(3)PO) with J-coupling J[H,F]=(10.99±0.013) Hz has been demonstrated. The LIA technique improves the SNR, and a 2.6-fold improvement in SNR over that of the frequency-adjusted averaging is achieved. To reduce the noise in EFNMR, it was suggested that the LIA technique and the first order gradient shim be used to achieve a subhertz linewidth.

  12. Design Study: ELENA Bending Magnet Prototype

    CERN Document Server

    Schoerling, D

    2013-01-01

    The ELENA bending magnet prototype shall prove that the proposed design meets the requirements set by the ELENA beam dynamics. The following points will be discussed in detail: (i) production process of a magnetic yoke diluted with stainless steel plates, (ii) the stability and repeatability of the field homogeneity of such a yoke over the full working range, (iii) choice of soft magnetic steel, (iv) hysteresis effects, (v) mechanical deformations, (vi) thermal insulation to intercept heat load from baking for activation of NEG coating in the vacuum chamber, (vii) end shim design. In order to verify these points the following measurements will be performed: (i) Hall probe scanning, (ii) integrated field homogeneity measurement (DC), (iii) integrated field homogeneity measurement (AC).

  13. Evaluation and demonstration of methods for improved fuel utilization. Fort Calhoun Poolside Inspection Programs: end-of-cycles 4 and 5

    Energy Technology Data Exchange (ETDEWEB)

    LaVake, J.C.; Smith, G.P.

    1980-08-01

    The purpose of this program is to demonstrate two techniques for improving fuel utilization in current Pressurized Water Reactors (PWR): (1) more efficient fuel management, and (2) high burnup. These improvements are being demonstrated in the Fort Calhoun reactor, a 1420 Mwt PWR. A more efficient fuel management scheme called SAVFUEL (Shimmed And Very Flexible Uranium Element Loading), will be demonstrated which reduces neutron leakage and is expected to reduce uranium requirements. Another part of the demonstration program will increase the fuel burnup of the current 14 x 14 fuel design to further reduce uranium requirements. The program is a joint Department of Energy (DOE), Omaha Public Power District (OPPD) and Combustion Engineering (C-E) endeavor and is part of a national effort to improve uranium utilization in light water reactors.

  14. 鱼腥草超微粉黄酮类成分HPLC指纹图谱的研究%Study on HPLC Fingerprint of Flavonoids in Ultramicro-powders of Houttuynia Cordata Thunb

    Institute of Scientific and Technical Information of China (English)

    刘建成; 黄一帆; 陈庆; 林珠灿; 郭素华; 俞道进

    2007-01-01

    利用高效液相色谱法建立了鱼腥草超微粉黄酮类成分的色谱指纹图谱.色谱条件:色谱柱为SHIM-PACK VP-G18柱(250mm×4.6 mm,10 μm),乙腈-1%甲酸梯度洗脱,流速为1.0 ml/min,检测波长254 nm.建立了鱼腥草超微粉HPLC指纹图谱,标定了7个共有峰.结论为利用HPLC指纹图谱可以较全面地控制鱼腥草超微粉的内在质量.

  15. An Improved Susceptibility Weighted Imaging Method using Multi-Echo Acquisition

    Science.gov (United States)

    Oh, Sung Suk; Oh, Se-Hong; Nam, Yoonho; Han, Dongyeob; Stafford, Randall B.; Hwang, Jinyoung; Kim, Dong-Hyun; Park, HyunWook; Lee, Jongho

    2013-01-01

    Purpose To introduce novel acquisition and post-processing approaches for susceptibility weighted imaging (SWI) to remove background field inhomogeneity artifacts in both magnitude and phase data. Method The proposed method acquires three echoes in a 3D gradient echo (GRE) sequence, with a field compensation gradient (z-shim gradient) applied to the third echo. The artifacts in the magnitude data are compensated by signal estimation from all three echoes. The artifacts in phase signals are removed by modeling the background phase distortions using Gaussians. The method was applied in vivo and compared with conventional SWI. Results The method successfully compensates for background field inhomogeneity artifacts in magnitude and phase images, and demonstrated improved SWI images. In particular, vessels in frontal lobe, which were not observed in conventional SWI, were identified in the proposed method. Conclusion The new method improves image quality in SWI by restoring signal in the frontal and temporal regions. PMID:24105838

  16. An evaluation of design characteristics for the water chemistry for SMART

    Energy Technology Data Exchange (ETDEWEB)

    Choi, B. S.; Kim, J. P.; Kim, H. Y.; Yoon, J. H.; Lee, D. J

    1998-07-01

    SMART does not have boron as a chemical shim using boron and does not operate purification system in power operation. However, the water chemistry applied in SMART still needs to meet the integrity and reliable operation requirements. This report reviews the corrosion resistance of the construction materials for SMART and the chemistry operating parameters qualitatively by comparing with those of PWR. The review shows that the construction materials for SMART, such as titanium alloys for steam generator tube materials and zirconium alloy for fuel cladding have good guarantee the integrity and reliability of the primary circuit and fuel cladding as well as the secondary circuit. This review results can be utilized as input data for SMART chemistry design, such as chemistry design guide, and chemistry manual. (author). 25 refs., 8 tabs., 17 figs

  17. On the suppression of background signals originating from NMR hardware components. Application to zero echo time imaging and relaxation time analysis.

    Science.gov (United States)

    Dreher, Wolfgang; Bardenhagen, Ingo; Huang, Li; Bäumer, Marcus

    2016-04-01

    Modern NMR imaging systems used for biomedical research are equipped with B0 gradient systems with strong maximum gradient strength and short switching time enabling (1)H NMR measurements of samples with very short transverse relaxation times. However, background signal originating from non-optimized RF coils may hamper experiments with ultrashort delays between RF excitation and signal reception. We demonstrate that two simple means, outer volume suppression and the use of shaped B0 fields produced by higher-order shim coils, allow a considerable suppression of disturbing background signals. Thus, the quality of NMR images acquired at ultrashort or zero echo time is improved and systematic errors in quantitative data evaluation are avoided. Fields of application comprise MRI with ultrashort echo time or relaxation time analysis, for both biomedical research and characterizing porous media filled with liquids or gases.

  18. HPLC法检验骨刺消痛胶囊中非法添加西药吡罗昔康%Determination of Piroxicam Adding Illegally in Guci Xiaotong Capsules by HPLC

    Institute of Scientific and Technical Information of China (English)

    赵艳; 付艳敏; 李伯军; 李冬梅

    2009-01-01

    目的 建立HPLC法检验骨刺消痛胶囊中非法添加西药吡罗昔康的检验方法.方法 采用shim-pack C18色谱柱,流动相:乙腈-0.5%冰醋酸溶液(60∶40);检测波长:243nm.结果 吡罗昔康对照品线性范围1.068~53.40μg·mL-1,r2=1,平均回收率为98.9%,RSD为2.1%(n=6).结论 定量方法简便,准确,专属性强.能有效地控制制剂的质量,打击假劣药品.

  19. Two-Dimensional Proton Chemical-Shift Imaging of Human Muscle Metabolites

    Science.gov (United States)

    Hu, Jiani; Willcott, M. Robert; Moore, Gregory J.

    1997-06-01

    Large lipid signals and strong susceptibility gradients introduced by muscle-bone interfaces represent major technical challenges forin vivoproton MRS of human muscle. Here, the demonstration of two-dimensional proton chemical-shift imaging of human muscle metabolites is presented. This technique utilizes a chemical-shift-selective method for water and lipid suppression and automatic shimming for optimal homogeneity of the magnetic field. The 2D1H CSI technique described facilitates the acquisition of high-spatial-resolution spectra, and allows one to acquire data from multiple muscle groups in a single experiment. A preliminary investigation utilizing this technique in healthy adult males (n= 4) revealed a highly significant difference in the ratio of the creatine to trimethylamine resonance between the fast and slow twitch muscle groups examined. The technique is robust, can be implemented on a commercial scanner with relative ease, and should prove to be a useful tool for both clinical and basic investigators.

  20. Magnet Design for the ISIS Second Target Station Proton Beam Line

    CERN Document Server

    Thomas, Chris; Jago, Stephen

    2005-01-01

    The ISIS facility, based at the Rutherford Appleton Laboratory in the UK, is an intense source of neutrons and muons for condensed matter research. The accelerator facility delivers an 800 MeV proton beam of 2.5x1013 protons per pulse at 50 Hz to the present target station. As part of a facility upgrade, it is planned to share the source with a second, 10 Hz, target station. The beam line supplying this target will extract from the existing target station beam line. Electromagnetic Finite Element Modelling techniques have been used to design the magnets required to meet the specified beam line optics. Kicker, septum, dipole, quadrupole, and steering magnets are covered. The magnet design process, involving 2D and 3D modelling, the calculation of ideal shims and chamfers, choice of steel, design of conducting coils, handling of heating issues and eddy current effects, is discussed.

  1. Beta Function Measurement in the Tevatron Using Quadrupole Gradient Modulation

    CERN Document Server

    Jansson, Andreas; Volk, James T

    2005-01-01

    Early in Run2, there was an effort to compare the different emittance measurements in the Tevatron (flying wires and synchtotron light) and understand the origin of the observed differences. To measure the beta function at a few key locations near the instruments, air-core quadrupoles were installed. By modulating the gradient of these magents and measuring the effect on the tune, the lattice parameters can be extracted. Initially, the results seem to disagree with with other methods. At the time, the lattice was strongly coupled due to a skew component in the main dipoles, caused by sagging of the cryostat. After a large fraction of the superconducting magnets were shimmed to remove a strong skew quadrupole component, the results now agree with expectations, confirming that the beta function is not the major error source of discrepancy in the emittance measurement.

  2. The study of acceptance and the transmission efficiency of separated sector cyclotron

    Directory of Open Access Journals (Sweden)

    Li Xiaoni

    2015-01-01

    Full Text Available In this paper we present the study of the transversal and longitudinal acceptance and the transmission efficiency in the injection, acceleration, and extraction systems in the separated sector cyclotron of the heavy ion research facility in Lanzhou, China. The study of cyclotron acceptance is done for 238U36+ with energy of 97 MeV/u and for 70Zn10+ with energy of 5.62 MeV/u under the theoretical isochronous and real magnetic field distribution. From the simulation results it can be seen that the transmission efficiency and the acceptances of separated sector cyclotron can be improved by redesign the curvature of MSI3 deflector or by introducing the magnet shim in MSI3 deflector region to change the distribution of the inner magnetic field. [Projekat Ministarstva nauke Republike Srbije, br. OI-171018

  3. Comparison of FEA Calculations with Cryostat Dummy Weight Test Results

    CERN Document Server

    Guarino, V

    2004-01-01

    Extensive Finite Element analyses were performed to determine the loads and stresses acting on the EB and Barrel during assembly and in its final configuration. Up to now it has been difficult to verify the FEA results due to the unusual compression at the inner radius shims has resulted in larger than anticipated deflections. The cryostat dummy load test offers the first real chance for a direct comparison between the deflections of the Tilecal and the FEA model. By comparing the difference in position of the FM's before the cryostat load was applied and afterwards it is possible to eliminate all other variables and compare directly with the FEA model. This paper will present a comparison between the FEA model and the survey measurements for when the cryostat dummy weight load was applied at 32 modules and 46 modules in place.

  4. Completely generalized multivalued nonlinear quasi-variational inclusions

    Directory of Open Access Journals (Sweden)

    Zeqing Liu

    2002-01-01

    Full Text Available We introduce and study a new class of completely generalized multivalued nonlinear quasi-variational inclusions. Using the resolvent operator technique for maximal monotone mappings, we suggest two kinds of iterative algorithms for solving the completely generalized multivalued nonlinear quasi-variational inclusions. We establish both four existence theorems of solutions for the class of completely generalized multivalued nonlinear quasi-variational inclusions involving strongly monotone, relaxed Lipschitz, and generalized pseudocontractive mappings, and obtain a few convergence results of iterative sequences generated by the algorithms. The results presented in this paper extend, improve, and unify a lot of results due to Adly, Huang, Jou-Yao, Kazmi, Noor, Noor-Al-Said, Noor-Noor, Noor-Noor-Rassias, Shim-Kang-Huang-Cho, Siddiqi-Ansari, Verma, Yao, and Zhang.

  5. Development of Nitrogen-Hydrocarbon Atmospheric Carburizing and Process Control Methods

    Science.gov (United States)

    Wang, Xiaolan; Zurecki, Zbigniew; Sisson, Richard D.

    2013-07-01

    Atmospheric pressure carburizing and neutral carbon potential annealing in nitrogen containing small additions of hydrocarbon gases can offer cost and steel surface quality alternatives to the comparable, endothermic atmosphere, or vacuum operations. An experimental program was conducted for refining real-time process control methods in carburizing of AISI 8620 steel under N2-CH4, N2-C3H8 blends containing <5 vol.% of hydrocarbon gas at 900 and 930 °C. Multiple types of gas analyzers were used to monitor residual concentrations of H2, CO, CO2, H2O, O2, CH4, C3H8, and other hydrocarbons inside furnace. A modified shim stock technique was additionally evaluated for correlation with gas analysis and diffusional modeling using measured carbon mass flux values (g/cm2/s). Results of this evaluation work are presented.

  6. Stray Capacitances of an Air-Cored Eddy Current Sensor

    Directory of Open Access Journals (Sweden)

    Yi Jia

    2009-12-01

    Full Text Available Stray capacitance of an air-cored eddy current sensor is one of the most crucial issues for successful development of an eddy current based residual stress assessment technology at frequency above 50 MHz. A two dimensional finite element model and an equivalent lumped capacitance network have been developed to accurately quantify overall stray capacitances of an air-cored eddy current sensor with specimen being tested. A baseline model was used to evaluate sensor design parameters, including the effects of pitch distance, trace width, trace thickness, number of turns, inner diameter, substrate thickness, lift-off distance, and dielectric constant of shim on the stray capacitances of the sensor. The results clearly indicate that an appropriate sensor design parameters could reduce the stray capacitance and improve the sensor performance. This research opens up a new design space to minimize stray capacitance effect and improve the sensor sensitivity and its lift-off uncertainty at elevated high frequencies.

  7. Design of a shielded coil element of a matrix gradient coil

    Science.gov (United States)

    Jia, Feng; Littin, Sebastian; Layton, Kelvin J.; Kroboth, Stefan; Yu, Huijun; Zaitsev, Maxim

    2017-08-01

    The increasing interest in spatial encoding with non-linear magnetic fields has intensified the need for coils that generates such fields. Matrix coils consisting of multiple coil elements appear to offer a high flexibility in generating customized encoding fields and are particularly promising for localized high resolution imaging applications. However, coil elements of existing matrix coils were primarily designed and constructed for better shimming and therefore are not expected to achieve an optimal performance for local spatial encoding. Moreover, eddy current properties of such coil elements were not fully explored. In this work, an optimization problem is formulated based on the requirement of local non-linear encoding and eddy current reduction that results in novel designs of coil elements for an actively-shielded matrix gradient coil. Two metrics are proposed to assess the performance of different coil element designs. The results are analyzed to reveal new insights into coil element design.

  8. Spread spectrum compressed sensing MRI using chirp radio frequency pulses

    CERN Document Server

    Qu, Xiaobo; Zhuang, Xiaoxing; Yan, Zhiyu; Guo, Di; Chen, Zhong

    2013-01-01

    Compressed sensing has shown great potential in reducing data acquisition time in magnetic resonance imaging (MRI). Recently, a spread spectrum compressed sensing MRI method modulates an image with a quadratic phase. It performs better than the conventional compressed sensing MRI with variable density sampling, since the coherence between the sensing and sparsity bases are reduced. However, spread spectrum in that method is implemented via a shim coil which limits its modulation intensity and is not convenient to operate. In this letter, we propose to apply chirp (linear frequency-swept) radio frequency pulses to easily control the spread spectrum. To accelerate the image reconstruction, an alternating direction algorithm is modified by exploiting the complex orthogonality of the quadratic phase encoding. Reconstruction on the acquired data demonstrates that more image features are preserved using the proposed approach than those of conventional CS-MRI.

  9. Multi-Slice Magnetic Resonance Imaging with the Dynamic Multi-Coil Technique

    Science.gov (United States)

    Juchem, Christoph; Nahhass, Omar M.; Nixon, Terence W.; de Graaf, Robin A.

    2015-01-01

    To date, spatial encoding for MRI is based on linear X, Y and Z field gradients generated by dedicated X, Y and Z wire patterns. We recently introduced the Dynamic Multi-Coil Technique (DYNAMITE) for the generation of magnetic field shapes for biomedical MR applications from a set of individually driven localized coils. The benefits for B0 magnetic field homogenization have been shown as well as proof-of-principle of radial and algebraic MRI. In this study the potential of DYNAMITE MRI is explored further and the first multi-slice MRI implementation is presented in which all gradient fields are purely DYNAMITE-based. The obtained image fidelity is shown to be virtually identical to a conventional MRI system with dedicated X, Y and Z gradient coils. Comparable image quality is a milestone towards the establishment of fully functional DYNAMITE MRI (and shim) systems. PMID:26419649

  10. Status report on GANIL

    CERN Document Server

    Fermé, J

    1979-01-01

    The GANIL heavy ion accelerator is composed of three isochronous cyclotrons in cascade. The first stage is a small compact cyclotron fitted with a conventional PIG source. The two following stages are two identical separated sector cyclotrons (K=400). The charge state of the ions is multiplied by a factor of 3.5 by the means of a stripper located between the two SSCs. The beam characteristics in the small injector cyclotron have been observed on a full scale working model at CERN in 1976. The shimming and the trim-coils for the two SSCs have been determined from magnetic measurements made on a one fourth model of the magnets. Recently an RF cavity, scale one third, has been realized and is under experiment. The magnets and vacuum chambers for the SSCs are already ordered. The accelerator is due to be in operation in 1982. (0 refs).

  11. ELISE NMR: Experimental liquid sealing of NMR samples

    Science.gov (United States)

    Wieruszeski, Jean-Michel; Landrieu, Isabelle; Hanoulle, Xavier; Lippens, Guy

    2006-08-01

    We present a simple, generally applicable approach to prevent sample evaporation when working at elevated temperatures in high resolution NMR. It consists of experimentally sealing the NMR sample by a second liquid (Experimental Liquid Sealing, ELISE). For aqueous samples, we identified the mineral oil commonly used in PCR application as the best candidate, because it contains only a very limited amount of water-soluble contaminants, is stable over time and heat resistant. The procedure does not interfere with shim settings, and is compatible with a wide variety of samples, including oligosaccharides and proteins. For chloroform samples, a simple drop of water allows to efficiently seal the sample, avoiding solvent evaporation even over lengthy time periods.

  12. Vertically Polarizing Undulator with Dynamic Compensation of Magnetic Forces

    Energy Technology Data Exchange (ETDEWEB)

    Strelnikov, N.; Vasserman, I.; Xu, J.; Jensen, D.; Schmidt, O.; Trakhtenberg, E.; Suthar, K.; Moog, E. R.; Pile, G.; Gluskin, E.

    2017-01-20

    As part of the R&D program of the LCLS-II project, a novel 3.4-meter-long undulator prototype with horizontal magnetic field and dynamic force compensation has recently been developed at the Advanced Photon Source (APS). Previous steps in this development were the shorter 0.8-meter-long and 2.8-meter-long prototypes. Extensive mechanical and magnetic testing was carried out for each prototype, and each prototype was magnetically tuned using magnetic shims. The resulting performance of the 3.4-meter-long undulator prototype meets all requirements for the LCLS-II insertion device, including limits on the field integrals, phase errors, higher-order magnetic moments, and electron-beam trajectory for all operational gaps, as well as the reproducibility and accuracy of the gap settings.

  13. [Preparation of ferulic acid, senkyunolide I and senkyunolide H from Ligusticum chuanxiong by preparative HPLC].

    Science.gov (United States)

    Xiong, Yao-Kun; Liang, Shuang; Hong, Yan-Long; Yang, Xiu-Juan; Shen, Lan; Du, Yan; Feng, Yi

    2013-06-01

    Preparative HPLC was used to prepare ferulic acid, senkyunolide I and senkyunolide H from Ligusticum chuanxiong. The separation was conducted on a Shim-Pack Prep-ODS (20.0 mm x 250 mm, 5 microm) column with the mobile phase of methanol-0.2% glacial acetic acid (50:50)at the flow rate of 5 mL x min(-1). The detection wavelength was 278 nm, and the purity of each compound was detected by HPLC analysis. Spectral data analyses including UV, ESI-MS and NMR were used to identify their structures. This method is simple, fast, which is suitable for preparation of standard reference of ferulic acid, senkyunolide I and senkyunolide H from L. chuanxiong and can meet the requirement of new drug research and development.

  14. RP-HPLC法测定地牡宁神口服液中马钱苷的含量%Determination the Content of Loganin in Dimuningshen Oral Liquid by RP-HPLC

    Institute of Scientific and Technical Information of China (English)

    栾瑞玲; 张华芸; 曲华玲

    2008-01-01

    目的:建立RP-HPLC法测定地牡宁神口服液中马钱苷的含量.方法:采用SHIMADZU Shim-pack vp-ODS(250 mm×4.6 mm, 5μm)色谱柱,流动相:甲醇-水-甲酸(30:69:1),检测波长:240nm流速:1.0 ml·min-1.结果:马钱苷的线性范围为0.16~5.56μg,r=0.9998,平均回收率为101.7%(RSD=1.5%,n=5).结论:方法简便、准确,可用于地牡宁神口服液的质量控制.

  15. Coupling field maps of combined function bending magnets to linear optics for the SESAME storage ring

    CERN Document Server

    Milanese, A

    2013-01-01

    This note provides several analyses of the combined function bending magnets of the SESAME storage ring. The objective is to develop tools to couple the magnetic design to the linear optics specifications. Such tools can be used to carry out a 3D field optimization, at the design phase and following magnetic measurements, in particular in order to fine tune the end shims on the poles. The analyses take as input field maps on the midplane, which are then processed in different ways to obtain linear transfer matrices for the optics, in the horizontal and vertical planes. Some peculiarities of this kind of magnet are also highlighted, for example, the slight variation of gradient along the arc. For convenience, the relative codes and scripts are included in the appendix.

  16. The relations between personality and language use.

    Science.gov (United States)

    Lee, Chang H; Kim, Kyungil; Seo, Young Seok; Chung, Cindy K

    2007-10-01

    The authors of this study provided basic descriptive data on the correlation between personality tests and Korean language use. Native Korean-speaking students (N = 80) at Pusan National University completed 2 personality tests, the Myers-Briggs Type Indicator (MBTI; I. B. Myers, M. H. McCaulley, N. L. Quenk, & A. L. Hammer, 1998) and the 5-Factor Inventory (0. P. John, E. M. Donahue, & R. L. Kentle, 1991). They completed a stream-of-consciousness essay, which the authors analyzed using the Korean version of Linguistic Inquiry and Word Count (KLIWC; C. H. Lee, J. Shim, & A. Yoon, 2005). Personality traits were significantly correlated with linguistic variables. Furthermore, the observed correlations between the two types of variables in Korean were consistent with the results of previous LIWC studies conducted in English. The authors discuss language use as a marker of personality.

  17. Minimax Current Density Coil Design

    CERN Document Server

    Poole, Michael; Lopez, Hector Sanchez; Ng, Michael; Crozier, Stuart; 10.1088/0022-3727/43/9/095001

    2010-01-01

    'Coil design' is an inverse problem in which arrangements of wire are designed to generate a prescribed magnetic field when energized with electric current. The design of gradient and shim coils for magnetic resonance imaging (MRI) are important examples of coil design. The magnetic fields that these coils generate are usually required to be both strong and accurate. Other electromagnetic properties of the coils, such as inductance, may be considered in the design process, which becomes an optimization problem. The maximum current density is additionally optimized in this work and the resultant coils are investigated for performance and practicality. Coils with minimax current density were found to exhibit maximally spread wires and may help disperse localized regions of Joule heating. They also produce the highest possible magnetic field strength per unit current for any given surface and wire size. Three different flavours of boundary element method that employ different basis functions (triangular elements...

  18. A method for longitudinal relaxation time measurement in inhomogeneous fields

    Science.gov (United States)

    Chen, Hao; Cai, Shuhui; Chen, Zhong

    2017-08-01

    The spin-lattice relaxation time (T1) plays a crucial role in the study of spin dynamics, signal optimization and data quantification. However, the measurement of chemical shift-specific T1 constants is hampered by the magnetic field inhomogeneity due to poorly shimmed external magnetic fields or intrinsic magnetic susceptibility heterogeneity in samples. In this study, we present a new protocol to determine chemical shift-specific T1 constants in inhomogeneous fields. Based on intermolecular double-quantum coherences, the new method can resolve overlapped peaks in inhomogeneous fields. The measurement results are in consistent with the measurements in homogeneous fields using the conventional method. Since spatial encoding technique is involved, the experimental time for the new method is very close to that for the conventional method. With the aid of T1 knowledge, some concealed information can be exploited by T1 weighting experiments.

  19. Multi-slice MRI with the dynamic multi-coil technique.

    Science.gov (United States)

    Juchem, Christoph; Nahhass, Omar M; Nixon, Terence W; de Graaf, Robin A

    2015-11-01

    To date, spatial encoding for MRI is based on linear X, Y and Z field gradients generated by dedicated X, Y and Z wire patterns. We recently introduced the dynamic multi-coil technique (DYNAMITE) for the generation of magnetic field shapes for biomedical MR applications from a set of individually driven localized coils. The benefits for B0 magnetic field homogenization have been shown, as well as proof of principle of radial and algebraic MRI. In this study the potential of DYNAMITE MRI is explored further and the first multi-slice MRI implementation in which all gradient fields are purely DYNAMITE based is presented. The obtained image fidelity is shown to be virtually identical to that of a conventional MRI system with dedicated X, Y and Z gradient coils. Comparable image quality is a milestone towards the establishment of fully functional DYNAMITE MRI (and shim) systems.

  20. Recriar o espaço de voz do poeta: a memória entre dois mundos

    Directory of Open Access Journals (Sweden)

    Joseilda de Sousa Diniz

    2010-01-01

    Full Text Available Poet, singer, reciter, engraver, who, after a tragic illness in the vocal cords became a researcher and a writer, José Alves Sobrinho was one of the main nomad poetsingers on Northeast Brazil. His name is linked to a period deemed the golden age of Brazilian cantoria and brings a privileged testimony of this effervescent moment, marked by the transition to new technologies of information. Deeply embedded in these changing times, where the sung word loses progressively space to the printed one, José Alves knew, cleverly, recreate a space of dialogue between the letter and the poem. Following his intellectual and artistic trajectory, we can realize the creative ability of this poet and his pears, in the sense of recreating the needed possibilities to the maintenance, spreading, adaptation and survival of his art.