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Sample records for sunder lal hora

  1. Er det økologisk madordninger ofte sundere?

    DEFF Research Database (Denmark)

    He, Chen

    Det europæiske skolemad system er under forandring, en forandring der er blevet kaldt den europæiske skolemad revolution af Morgan & Sonnino (2008). Forandringen består af to afgørende søjler/indsatsområder; 1) Krav til sundere kostvaner; 2) Flere økologiske fødevarer. Denne forskning harundersøg...

  2. Ensayo del lisado de amebocitos del Limulus (LAL

    Directory of Open Access Journals (Sweden)

    Rolando Perdomo Morales

    2004-04-01

    Full Text Available En los últimos años, los principales organismos reguladores de productos farmacéuticos (Farmacopeas exigen cada vez más en sus monografías la aplicación del método del lisado de amebocitos de Limulus (LAL para la liberación de pirógenos en productos terminados parenterales. El análisis de pirógenos constituye uno de los principales ensayos en el control de calidad de la fabricación de inyectables por su repercusión en la salud humana, puesto que la presencia y administración de los mismos, es capaz de provocar una serie de respuestas fisiológicas, en su mayoría de carácter perjudicial y en casos extremos, la muerte del paciente. Por las razones anteriores, existe un creciente interés en el conocimiento y dominio de estos métodos. El presente trabajo muestra una revisión bibliográfica del método del LAL, se tratan aspectos como su descubrimiento y estandarización, aparición en la industria farmacéutica y razones para su triunfo, y los basamentos de los principales métodos o variaciones comerciales del LAL (gelificación, turbidimétricos y cromogénicos que se describen en las Farmacopeas.

  3. Ensayo del lisado de amebocitos del Limulus (LAL

    Directory of Open Access Journals (Sweden)

    Rolando Perdomo Morales

    Full Text Available En los últimos años, los principales organismos reguladores de productos farmacéuticos (Farmacopeas exigen cada vez más en sus monografías la aplicación del método del lisado de amebocitos de Limulus (LAL para la liberación de pirógenos en productos terminados parenterales. El análisis de pirógenos constituye uno de los principales ensayos en el control de calidad de la fabricación de inyectables por su repercusión en la salud humana, puesto que la presencia y administración de los mismos, es capaz de provocar una serie de respuestas fisiológicas, en su mayoría de carácter perjudicial y en casos extremos, la muerte del paciente. Por las razones anteriores, existe un creciente interés en el conocimiento y dominio de estos métodos. El presente trabajo muestra una revisión bibliográfica del método del LAL, se tratan aspectos como su descubrimiento y estandarización, aparición en la industria farmacéutica y razones para su triunfo, y los basamentos de los principales métodos o variaciones comerciales del LAL (gelificación, turbidimétricos y cromogénicos que se describen en las Farmacopeas.

  4. Limulus amebocyte lysate technique (LAL) for bacterial endotoxin control in radiodiagnosis agents (kits) and radioisotopes

    International Nuclear Information System (INIS)

    Morote, M.; Robles, A.; Ramos, B.; Otero, M.

    1997-01-01

    A procedure based on a fast technique of LAL individual kits has been devised to control bacterial endotoxins in radiodiagnosis agents (RDA): HEMTEC, DEIDA, PPI, AMD, GHCa, RENTEC, DMSA, MAA, TSC, HERTEC, DTPA, BRATEC and EDTMP as well as in radioisotopes I-131 and Tc99m. The procedures begins with the determination of the following values, injection volume (IV), endotoxin limits (EL), maximum valid dilution (MVD), total mass (TM), reconstitution volume (RV), concentration (mg/ml), and final dilution (FD). Subsequently, a procedure is carried out to conduct an 'in vitro' control of the radiodiagnosis agents and radioisotopes with LAL individual kits; the procedures includes: reconstitution of the sample to be controlled, dilution, inoculation of the diluted sample in LAL tubes and incubation at 37 o C for an hour. Finally, results are interpreted through the observation of gel formation or not in LAL tubes

  5. Ecological Assessment of Lake Hora, Ethiopia, Using Benthic and ...

    African Journals Online (AJOL)

    Bheema

    Lake Hora needs protection management strategies to maintain its sustainable use. Key words: Benthic Fauna, Ethiopia, Lake Hora, Specimens, Weed-bed. 1. ..... Loam soils often contain a good amount of organic matter. 3.3. Ecological ...

  6. HORA - an Austrian platform for natural hazards

    Science.gov (United States)

    Hlatky, T.

    2009-04-01

    HORA - an Austrian platform for natural hazards as a new way in risk communication One initiatives launched in Austria demonstrate that public participation not only bears the risk of a partial transfer of responsibility by the authorities; it may above all prepare the ground for entirely new approaches and create new links. The recent installation of the first internet risk zoning system in Austria underscores the importance of involving private parties in natural disaster protection. This public-private partnership (PPP) between the Federal Ministry of Agriculture, Forestry, Environment and Water Management (BMLFUW) and the Austrian Insurance Association (VVO) was launched in the wake of the 2002 flood disaster. The first project phase, the Austrian flood risk zoning system called HORA (screenshot see fig. 1), has now been accessible on the Web since 1st June 2006. In accordance with a risk partnership concluded between federal government, insurance companies and private parties, the project initiators seek to offer the public a preliminary risk assessment tool for evaluation of their home, industrial enterprise, of infrastructure. Digital risk maps shall provide information on 30-year, 100-year and 200-year flood events as they occur alongside the 26.000-km-long domestic river network. The probability with which a certain block of land is immersed in water during a flood event can be calculated by means of hydraulic engineering methods. These have traditionally relied on statistical figures, which are known to be very inaccurate, especially when major events such as flooding are concerned. The Vienna University of Technology (TU) (Institute of Hydraulic and Water Resources Engineering) has dedicated many years to developing more accurate, process oriented risk assessment techniques. The starting points was to identify different flood-triggering processes and to divide them into specific categories as long-duration rainfalls, short-duration rainfalls, storms

  7. Kapoor, Dr Shyam Sunder

    Indian Academy of Sciences (India)

    Date of birth: 14 June 1938. Specialization: Nuclear Physics, Nuclear Radiation Detectors, Accelerator-based Research and Development & Applications in Nuclear Energy Address: A/3, Banganga, Govandi Station Road, Deonar, Mumbai 400 088, Maharashtra Contact: Residence: (022) 2550 4301. Mobile: 93235 04942

  8. Preliminary study fo the interference of proteic compounds of radiopharmaceuticals in the test of lisadode amebocitos de limulus (LAL)

    International Nuclear Information System (INIS)

    Aldana, Claudia

    1997-01-01

    In this thesis the objective was evaluate the interference of proteic compounds of the radiopharmaceuticals in the test LAL (lisado of amebocitos de limulus) for this, macroagregates of albumina (MAA) was used with metilendifosfonato (MDP) as control that is the radiopharmaceutical more used in the nuclear medicine centers of the country. Initially preliminary test were carried out to assess if some of two radiopharmaceuticals would cause interference with LAL test, after the test was validated and finally routine tests were made. With the preliminary assays was concluded that proteic compounds did not cause interference (albumina with a concentration of 2 md/dl) with the MAA. However with the MDP cause interference with LAL test. The interference was eliminated with a dilution of 1:8 of the sample. Was concluded that the success of LAL test depends on conditions such as temperature, pH, constant incubation (no minimum variations) and that is a good test for quality control of the radiopharmaceuticals

  9. Measurement of endotoxin levels in blood of hemodialysis Patients by 'Lal' test and comparision of its efficacy with blood culture

    Directory of Open Access Journals (Sweden)

    Gh Vazirzadeh

    2006-01-01

    Full Text Available Introduction: Presently, bacteremia is the principal cause of morbidity in patients undergoing hemodialysis. Gram-negative bacteria account for approximately 50 percent of documented infections. Endotoxins released during lysis of gram negative bacteremia result in inflammatory and defense response by the body and if not treated promptly result in septic shock and ultimately death of the patient. This study describes the detection of endotoxins in blood of patients with bacteremia due to gram - negative bacteria by LAL test. Method: Blood samples of 278 hemodialysis patients were analyzed in this study and pathogens were isolated from blood culture samples. Then, their antibiotic sensitivity was determined. In patients with positive blood culture, endotoxin levels were measured by LAL-test. Results: Frequency of bacteremia in patients was 13.6% . The prevalence of gram – negative bacteremia was 44.7%. E coli were the major pathogens, while staphylococcus aureus was the most common gram positive bacterium. Endotoxin was detected in 15 patients (3.8 ± 1.08 EU/ml . The sensitivity and specificity of endotoxins for gram – negative bacteremia were 88% and 95%, respectively. Conclusion: The results indicate that the LAL method is a fast, sensitive and simple method. There was no significant difference between the results of blood culture and LAL – test ( P > 0.05 .

  10. Time and management : the need for hora management

    NARCIS (Netherlands)

    Karsten, L; Leopold, J

    2003-01-01

    Working time patterns are moving away from the traditional pattern of regularity, standardisation and co-ordination to a new triptych of individualism, heterogeneity and irregularity. Seeks to make sense of these changes through the concept of hora management as an approach to manage the interface

  11. Validation of the L.A.L. technique (gel cloth) in radiodiagnosis and radioisotopes

    International Nuclear Information System (INIS)

    Morote, M.; Otero, M.; Chavez, G.

    1999-01-01

    Based on the validation of the LAL technique (gel cloth), real endotoxin limits (EL), expressed in endotoxin units per milliliter (EU/mL), as well as maximum dilution volume (MDV) were determined in seven radiodiagnosis agents (RDA): medronate, pentetate, sulfur colloid, albumin macroaggregated, succimer, disofenin, and pyrophosphates, which showed M.D.V. values of: 1:80; 1:16; 1:128; 1:64; 1:4; 1:128; 1:64 and EL of 20 EU/mL; 4 EU/mL; 32 EU/mL; 16 EU/mL; 1 EU/mL and 16 EU/mL, respectively. Radioisotope Tc-99m presents a MDV of 1:1 and an EL below 0,25 EU/mL. Clear interference in the acidity of sulfur colloid (pH below 2) was also found against pyrotell reaction, even in the sixth dilution of the product. M.D.V. results also showed that dilutions are even 100 times smaller than the theoretical values

  12. Performances of the Alpha-X RF gun on the PHIL accelerator at LAL

    Science.gov (United States)

    Vinatier, T.; Bruni, C.; Roux, R.; Brossard, J.; Chancé, S.; Cayla, J. N.; Chaumat, V.; Xu, G.; Monard, H.

    2015-10-01

    The Alpha-X RF-gun was designed to produce an ultra-short (laser-driven plasma accelerator with a short wavelength accelerating medium. It has been demonstrated on PHIL (Photo-Injector at LAL) that the coaxial RF coupling, chosen to preserve the gun field cylindrical symmetry, is perfectly understood and allows reaching the required peak accelerating field of 100 MV/m giving beam energy of 6.3 MeV. Moreover, a quite low beam rms relative energy spread of 0.15% at 3.8 MeV has been measured, completely agreeing with simulations. Dark current, quantum efficiencies and dephasing curves measurements have also been performed. They all show high values of the field enhancement factor β, which can be explained by the preparation of the photocathodes. Finally, measurements on the transverse phase-space have been carried out, with some limitations given by the difficult modelization of one of the PHIL solenoid magnets and by the enlargement of the beam transverse dimensions due to the use of YAG screens. These measurements give a normalized rms transverse emittance around 5π mm mrad, which does not fulfill the requirement for the Alpha-X project.

  13. A lab-on-phone instrument with varifocal microscope via a liquid-actuated aspheric lens (LAL)

    Science.gov (United States)

    Fuh, Yiin-Kuen; Lai, Zheng-Hong; Kau, Li-Han; Huang, Hung-Jui

    2017-01-01

    In this paper, we introduce a novel concept of liquid-actuated aspheric lens (LAL) with a built-in aspheric polydimethylsiloxane lens (APL) to enable the design of compact optical systems with varifocal microscopic imaging. The varifocal lens module consists of a sandwiched structures such as 3d printed syringe pump functionally serves as liquid controller. Other key components include two acrylic cylinders, a rigid separator, a APL/membrane composite (APLMC) embedded PDMS membrane. In functional operation, the fluidic controller was driven to control the pressure difference and ALPMC deformation. The focal length can be changed through the pressure difference. This is achieved by the adjustment of volume change of injected liquid such that a widely tunable focal length. The proposed LAL can transform to 3 modes: microscopic mode (APLMC only), convex-concave mode and biconcave mode. It is noticeable that LAL in the operation of microscopic mode is tunable in focus via the actuation of APLMC (focal length is from 4.3 to 2.3 mm and magnification 50X) and can rival the images quality of commercial microscopes. A new lab-on-phone device is economically feasible and functionally versatile to offer a great potential in the point of care applications. PMID:28650971

  14. Performances of the Alpha-X RF gun on the PHIL accelerator at LAL

    Energy Technology Data Exchange (ETDEWEB)

    Vinatier, T., E-mail: vinatier@lal.in2p3.fr [Laboratoire de l' Accélérateur Linéaire (LAL), Université Paris Sud, UMR 8607, bâtiment 200, 91898 Orsay Cedex (France); Bruni, C. [Laboratoire de l' Accélérateur Linéaire (LAL), Université Paris Sud, UMR 8607, bâtiment 200, 91898 Orsay Cedex (France); Roux, R. [Laboratoire de l' Accélérateur Linéaire (LAL), Université Paris Sud, UMR 8607, bâtiment 200, 91898 Orsay Cedex (France); Laboratoire d' Etude des Eléments Légers, CEA IRAMIS, bâtiment 524, 91191 Gif sur Yvette Cedex (France); Brossard, J. [Laboratoire de l' Accélérateur Linéaire (LAL), Université Paris Sud, UMR 8607, bâtiment 200, 91898 Orsay Cedex (France); Laboratoire Astroparticule et Cosmologie, Université Paris 7, UMR 7164, bâtiment Condorcet, 75205 Paris Cedex (France); Chancé, S.; Cayla, J.N.; Chaumat, V. [Laboratoire de l' Accélérateur Linéaire (LAL), Université Paris Sud, UMR 8607, bâtiment 200, 91898 Orsay Cedex (France); and others

    2015-10-11

    The Alpha-X RF-gun was designed to produce an ultra-short (<100 fs rms), 100 pC and 6.3 MeV electron beam with a normalized rms transverse emittance of 1π mm mrad for a gun peak accelerating field of 100 MV/m. Such beams will be required by the Alpha-X project, which aims to study a laser-driven plasma accelerator with a short wavelength accelerating medium. It has been demonstrated on PHIL (Photo-Injector at LAL) that the coaxial RF coupling, chosen to preserve the gun field cylindrical symmetry, is perfectly understood and allows reaching the required peak accelerating field of 100 MV/m giving beam energy of 6.3 MeV. Moreover, a quite low beam rms relative energy spread of 0.15% at 3.8 MeV has been measured, completely agreeing with simulations. Dark current, quantum efficiencies and dephasing curves measurements have also been performed. They all show high values of the field enhancement factor β, which can be explained by the preparation of the photocathodes. Finally, measurements on the transverse phase-space have been carried out, with some limitations given by the difficult modelization of one of the PHIL solenoid magnets and by the enlargement of the beam transverse dimensions due to the use of YAG screens. These measurements give a normalized rms transverse emittance around 5π mm mrad, which does not fulfill the requirement for the Alpha-X project.

  15. Acéphale e a hora presente

    OpenAIRE

    Scheibe, Fernando

    2000-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Esta dissertação busca, a partir da leitura cruzada de dois periódicos extremamente díspares do imediato pré-segunda-guerra, o francês Acéphale, encabeçado por Georges Bataille e o brasileiro Cadernos da Hora Presente, dirigido por Tasso da Silveira, contribuir para a discussão sobre os impasses das vanguardas artísticas nesse período. Questiona-se aqui a proposta de uma "solução religiosa" ...

  16. Arte y literatura: develadores de la hora cero de Nicaragua

    Directory of Open Access Journals (Sweden)

    Maricela Kauffmann

    1999-02-01

    Full Text Available La historia reciente de Nicaragua está llena de períodos transidos de violencia. La violencia institucional legitimada desde la voluntad de los grupos de poder: torturas, asesinatos, resistencia, ha provocado una violencia soberana desde los sectores organizados de la sociedad civil: insurrección y lucha guerrillera, revolución y guerra civil han sido expresiones concretas de la voluntad ciudadana. La serie pictórica Guerrilleros Muertos (1958 de Armando Morales, la realidad política y social recogida en el poema La Hora Cero (1958 de Ernesto Cardenal, las instalaciones Vacíos II: Desaparecidos de Patricia Belli y Caja de Arena de María José Zamora, realizadas en el marco de la tragedia nacional que destapó e incrementó el huracán Mitch, son expresiones artísticas que contribuyen a generar lo que Walter Benjamín plantea como la voluntad soberana que deben ejercer los y las ciudadanas para develar y erradicar las formas de poder, corrupción y violencia que les agobian y oprimen.

  17. Achado dunhas lousas con arte megalítico en Fonte Tourón Lalín, Pontevedra

    Directory of Open Access Journals (Sweden)

    Cabrejas Domínguez, Elena

    2009-12-01

    Full Text Available In an archaeological context before a works execution took place (an electric half tension line, some engraved gravestones were found around the area of Fonte Touron, Council of Lalín. These gravestones have engravings representative of megalithism and nowadays they became boundary markers of the yards in which they are. The features of the engravings, besides the very shape of the stones and the context where other mounds are located, and above everything, the information provided by local neighbors that relate the stones of this mound to one set apart some years ago, points that they were part of a megalithic monument, and it is highly probable that they were the orthostats of a chamber.

    No contexto dos traballos arqueolóxicos previos á execución dunha obra (unha liña eléctrica de media tensión, localizáronse unhas lousas con gravados na zona de Fonte Tourón, en Lalín. Trátase dunhas lousas que presentan uns gravados de estilo propio do megalitismo e que agora forman parte dos lindes das fincas nas que se atopan. As características destes gravados, sumado á propia forma das pedras, a un contexto onde se localizan outras mámoas e sobre todo, á información dos veciños que vinculan estas pedras cunha mámoa desfeita fai uns anos, apuntan a que formaron parte dun monumento megalítico, e que moi probablemente se trata dos esteos dunha cámara.

  18. Planeta(s) remisión de V. hora de los planeta(s).

    OpenAIRE

    2011-01-01

    [ES] Definición del término Planeta(s) remisión de V. hora de los planeta(s). en el diccionario Dicter. [EN] Definition of the word Planeta(s) remisión de V. hora de los planeta(s). in the dictionary Dicter.

  19. Hora do jogo: os professores estão prontos?

    Directory of Open Access Journals (Sweden)

    Eliana Maria Magnani

    2018-04-01

      Hora del juego: ¿los profesores están preparados? RESUMEN Las ideas discutidas en este texto están relacionadas con las actividades de enseñanza, investigación y extensión desarrolladas desde 2012 a través de la Universidad Estadual de Oeste de Paraná – UNIOESTE. El artículo señala la importancia de la clasificación y catalogación de juegos educativos, explicitando qué es un importante conocimiento propuesto a los Centros Municipales de Educación Infantil (CMEIs, localizados en una ciudad del Suroeste de Paraná, CMEIs que, en función de una ley local, empezaron la (re implementación de ludotecas en 2007. La metodología se efectuó en fases, dos de dichas fases fueron significativas para la revisión de la implementación, a saber: diagnóstico de cómo se organizaban los materiales existentes en las ludotecas, curso sobre la importancia de la clasificación y catalogación de diferentes tipos de juegos. Para ello, toda revisión se apoyó en las ideas de Jean Piaget (2010/1946, 1994/1932, quien elaboró una teoría sobre el juego. Dichos conocimientos sirvieron para la comprensión de que los maestros no están preparados para este tipo de actividad didáctico-pedagógica, pues dicha educación es un proceso que demanda toma de conciencia de propia praxis, la cual requiere el (re aprendizaje a respecto de los objetivos de diferentes tipos de juegos y del desarrollo infantil, siendo que ello necesita ocurrir en la formación inicial y en la formación continua de profesores. Por consiguiente, es necesaria la involucración de los (futuros profesores en actividades lúdicas de enseñanza, investigación y extensión realizadas en universidades. Palabras clave: Clasificación de Juegos. Educación Infantil. Formación docente.

  20. Estandarización del ensayo del lisado de amebocitos de Limulus (LAL:: método de gelificación

    Directory of Open Access Journals (Sweden)

    Rolando Perdomo Morales

    2004-04-01

    Full Text Available Entre las principales aplicaciones del método del lisado de amebocitos de Limulus (LAL está el control de endotoxinas en producto final de drogas parenterales. Para la aplicación exitosa del ensayo se requiere del dominio de un conjunto de habilidades, por lo que usualmente se corre en laboratorios especializados que ya cuentan con una basta experiencia. Aunque ya es un método ampliamente establecido y conocido, la aplicación del ensayo puede ser laborioso, consumir tiempo y reactivos hasta la obtención de resultados correctos. En el presente trabajo se describe la estandarización del ensayo del LAL por el método de gelificación. Se evalúan varias estrategias con la finalidad de optimizar y/o reducir el tiempo total de ensayo, el empleo de materiales como puntas certificadas libres de endotoxinas, tubos de ensayo y la sustitución de agua libre de endotoxinas suministrada por los fabricantes de reactivo LAL por agua para inyección. El procedimiento estandarizado produce resultados válidos según los criterios de la Farmacopea de EE.UU.The control of endotoxins in the final product of parenteral drugs is among the main applications of the limulus amebocyte lysate (LAL. For the successful application of this test, it is necessary to have a thorough knowledge of a series of abilities. That's why, it is usually made at specialized laboratories having a vast experience. In spite of the fact that it is already a widely established and known method, the application of the assay may be laborious, take time and consume reagents until the obtention of the right results. In the present paper, it is described the standardization of the LAL assay by the gelification method. Various strategies are evaluated in order to optimize and/or reduce the total time of the assay, the use of materials as certified endotoxin-free points, test tubes, and the substitution of endotoxin-free water, supplied by the manufacturers of LAL reagent, by injection water

  1. Highly active antiretroviral therapy and outcome of AIDS-related Burkitt's lymphoma or leukemia. Results of the PETHEMA-LAL3/97 study.

    Science.gov (United States)

    Oriol, Albert; Ribera, Josep-Maria; Brunet, Salut; del Potro, Eloy; Abella, Eugènia; Esteve, Jordi

    2005-07-01

    Short, intensive cycles of chemotherapy have resulted in improved survival in BurkittOs lymphoma/leukemia (BL) in adults. The prognosis of patients with immunodeficiency virus (HIV)-associated BL is considered to be poor, but these patients have seldom been treated with BL-specific protocols. However, a study (PETHEMA-LAL3/97) in which patients with BL were treated regardless of their HIV status failed to find differences between HIV-infected and immunocompetent individuals. Furthermore, patients who received highly active antiretroviral therapy (HAART) seemed to have a slightly better disease-free survival than those who did not (p=0.051). We extended the follow-up analysis to elucidate the role of HAART in the survival of HIV-infected patients included in the PETHEMA-LAL3/97 protocol.

  2. A dimensão musical de lalíngua e seus efeitos na prática com crianças autistas

    Directory of Open Access Journals (Sweden)

    Beatriz Alves Viana

    Full Text Available Resumo Este artigo resulta da experiência com autistas em uma extensão universitária articulada à rede de saúde mental e a um serviço de psicologia. Investiga-se a relação de lalíngua com a música e estabelece suas contribuições à clínica do autismo. Para tanto, foi feita a leitura de textos nos campos da psicanálise e da música. Como material explorado, utilizaram-se relatos de experiência de profissionais e trabalho no grupo de extensão. A relação de lalíngua com a música é apresentada a partir da consideração dos jogos rítmicos de presença e ausência do som no decorrer do tempo que trazem elementos marcantes à própria constituição do sujeito, situando-nos diante de uma diacronia, também presente em lalíngua. Com isso, pode-se pensar como o estudo desse conceito nos auxilia na compreensão da relação primordial do sujeito com Outro, especialmente no autismo.

  3. flyLAL покоряет Эстонию / Екатерина Таклая

    Index Scriptorium Estoniae

    Таклая, Екатерина

    2009-01-01

    Leedule kuuluv lennufirma Avia Solutions Group lõi Eestisse lennufirma flyLAL Charters Eesti, millega sõlmisid lepingud TEZ Tour, Novatours ja Horizon Travel. Estonian Air ei pea uut firmat konkurendiks

  4. El duelo y el tiempo mítico en Rosa Cuchillo y La hora azul

    OpenAIRE

    Torres Oyarce, Tania

    2017-01-01

    In this paper, I propose that the novels Rosa Cuchillo and La hora azulproject individual processes of mourning in a mythical social order thatlimits itself to reproduce the phantom of the enclosed nation (Ubilluz) asa (seudo) proposal to solve the internal conflict that took place in Perubetween 1980-2000. In Rosa Cuchillo the main character, Rosa Cuchillo,goes through a process of mourning due to the loss of his terrorist son,Liborio, whereas in La hora azul the main character, Adrián Ormac...

  5. El duelo y el tiempo mítico en Rosa Cuchillo y La hora azul

    OpenAIRE

    Torres Oyarce, Tania

    2017-01-01

    En este artículo, sostenemos que las novelas Rosa Cuchillo y La hora azul proyectan procesos individuales de duelo en un orden social mítico que se limita a reproducir el fantasma de la nación cercada (Ubilluz) como (seudo) propuesta de solución al conflicto armado acontecido en el Perú entre 1980-2000. En Rosa Cuchillo, la protagonista Rosa Cuchillo atraviesa un proceso de duelo por haber perdido a su hijo subversivo, Liborio, mientras que, en La hora azul, el protagonista Adrián Ormache suf...

  6. Aplicación web para la gestión de una bolsa de horas

    OpenAIRE

    Ávila Hernández, Alberto de

    2012-01-01

    El presente documento describe las distintas fases asociadas al diseño y desarrollo de una herramienta que tiene por objetivo informar al usuario del estado de la bolsa de horas de soporte que tiene contratada una determinada empresa. La funcionalidad principal de la aplicación es permitir al usuario conocer cuántas horas de soporte le restan, cuántas han sido consumidas y en qué tareas han sido empleadas, así como obtener distintos tipos de estadísticas con los datos asociados a esta informa...

  7. Chopra, Prof. Virender Lal

    Indian Academy of Sciences (India)

    Ethical Guidelines and Procedures document. Posted on 17 January 2017. A revised version of the document 'Scientific Values: Ethical Guidelines and Procedures' has been produced by the Academy's Panel on Scientific Values. For more details, see the Academy Committee on Scientific Values page.

  8. Horae canonicae”, España y los dos Auden

    Directory of Open Access Journals (Sweden)

    Insausti, Gabriel

    2013-08-01

    Full Text Available “Horae canonicae”, the series first included in The Shield of Achilles when first published, with the Crucifixion as its central theme, is one the most crucial pieces of the later Auden. Criticism has often located these poems within the contexto f Auden’s conversión to Christianity and his ideological bias towards a growing conservatism alter his early years, in which he flirted with revolutionary leftism. However, “Horae canonicae” contains several enigmatic elements on which the reader should focus, elements that allow us to read it as a sort of palinode whose intertext would be pieces like the much better known “Spain”.“Horae canonicae”, la serie de poemas incluida en The Shield of Achilles con el Gólgota por tema central, constituye una de las piezas más importantes del Auden de los años cincuenta. La crítica ha situado habitualmente este conjunto en el contexto del cristianismo ulterior del poeta y su evolución ideológica hacia un tibio conservadurismo, tras unos años de juventud en los que coqueteó con el izquierdismo revolucionario. No obstante, “Horae canonicae” contiene algunos elementos sumamente enigmáticos sobre los que conviene llamar la atención, y que permiten leer el texto como una suerte de palinodia cuyo intertexto serían poemas como el célebre “Spain”.

  9. Horas variables, días de la semana y astronomía

    OpenAIRE

    Gangui, Alejandro

    2017-01-01

    Los días, los años y la sucesión de estaciones nos vienen dados por la naturaleza; las horas y las semanas son construcciones culturales. En la antigüedad greco-romana, la duración de las horas variaba con las estaciones, lo que desapareció hoy, pero hemos conservado los nombres dados por esa cultura a muchos días de la semana, los que hacen referencia a su astronomía y su mitología. ¿Por qué están los días en el orden que conocemos? Fil: Gangui, Alejandro. Consejo Nacional de Investigació...

  10. Sono e adolescência: quantas horas os adolescentes precisam dormir?

    Directory of Open Access Journals (Sweden)

    Érico Felden Pereira

    2015-03-01

    Full Text Available Objetivo Determinar a especificidade e a sensibilidade de uma medida para apontar o melhor ponto de corte para a duração de sono como preditor da sonolência diurna excessiva em adolescentes. Métodos Participaram do estudo 1.359 adolescentes, com idades de 14 a 21 anos, de duas cidades do sul do Brasil, que responderam a questionário de hábitos de sono e sonolência diurna. Utilizou-se a Receiver Operating Characteristic para estimar a capacidade preditiva da duração de sono para a sonolência diurna excessiva. Resultados A média de duração do sono para os adolescentes com sonolência diurna excessiva foi de 7,9 horas e para aqueles sem sonolência diurna excessiva foi de 8,33 horas (p < 0,001. A prevalência de sonolência diurna excessiva foi de 35,7%. Foi observada correlação significativa e negativa entre a duração do sono e as idades analisadas (p < 0,001. A análise de Receiver Operating Characteristic indicou duração mínima de 8,33 horas como proteção para a sonolência diurna excessiva. Conclusão Foi observada alta prevalência de sonolência diurna excessiva e propõe-se como possível duração de sono um mínimo de 8,33 horas nos dias com aula para que os adolescentes evitem esse desfecho.

  11. Vinařická hora Hill Cenozoic Composite Volcano, Central Bohemia: Geochemical Contraints

    Czech Academy of Sciences Publication Activity Database

    Řanda, Zdeněk; Novák, Jiří Karel; Balogh, K.; Frána, Jaroslav; Kučera, Jan; Ulrych, Jaromír

    2003-01-01

    Roč. 15, - (2003), s. 126 ISSN 1210-9606. [International Conference HIBSCH 2002 Symposium. Teplá near Třebenice, 03.06.2002-08.06.2002] R&D Projects: GA AV ČR IAA3048201 Institutional research plan: CEZ:AV0Z3013912; CEZ:AV0Z1048901 Keywords : Bohemian massif * Vinařická hora Hill * geochemistry Subject RIV: DD - Geochemistry

  12. Clarice Lispector and the Historical Context in "A Hora da Estrela" Clarice Lispector e a contracena da História em A hora da estrela

    Directory of Open Access Journals (Sweden)

    Isabel Virginia de Alencar Pires

    2011-07-01

    Full Text Available Este artigo aborda o livro "A hora da estrela", de Clarice Lispector, à luz dos pressupostos da Teoria da Recepção, de Jauss, que leva em conta o contexto histórico nas análises literárias. Publicada em fins de 1977, essa obra – que conta a história de Macabéa, uma nordestina que, “sem saber como nem por que”, acaba indo morar no “inacreditável Rio de Janeiro” – é considerada por diversos estudiosos como a “mais explicitamente social” da autora, pois até então os livros clariceanos costumavam ser recorrentemente acusados pela crítica da época de se “alhearem” da realidade, dedicando-se predominantemente a abordagens de caráter psicológico e deixando de lado o contexto político e social. Em A hora da estrela, a temática social passa a ser mais explícita, verificando-se assim uma espécie de “ruptura” na trajetória literária clariceana, interrompida no mesmo ano de publicação da obra, com a morte da autora. Este artigo busca apreender, nas entrelinhas do texto, as marcas que o diálogo do último livro lançado em vida pela escritora, durante o período do autoritarismo brasileiro, realiza com o seu contexto de surgimento. Para tanto, o estudo faz ainda uma aproximação entre o último livro de Clarice Lispector e o cinema de Glauber Rocha. This article contemplates Clarice Lispector’s “A hora da estrela” (The Hour of the Star, based on Jauss´ Reception Theory, which takes into account the historical context in literary analyses. Published in late 1977,  this work – which tells the story of Macabéa - a natural born northeast Brazilian woman that “not knowing why or how” moves to the “unbelievable city of Rio de Janeiro” – is considered by many scholars the “most explicitly social” one  done by the author. Up to that moment, her books had frequently been accused by critics of “deviating” from reality, focusing predominantly on psychological features and leaving social

  13. Spiser vindrikkere sundere end øldrikkere?

    DEFF Research Database (Denmark)

    Johansen, Ditte; Friis, Karina; Skovenborg, Erik

    2007-01-01

    In a cross sectional study based on information on the number, type of item and total charge of 3(1/2) million transactions over a period of 6 months in various supermarkets in Denmark we examined whether people who buy wine also buy healthier food items than those who buy beer. We found that win...... buyers bought more olives, fruit and vegetables, poultry, cocking oil and low fat cheese, milk and meat than beer buyers who bought more ready cooked meals, sugar, cold cuts, chips, pork, butter or margarine, sausages, lamb and soft drinks than wine buyers....

  14. Residents’ Awareness of Urban and Social Living Quality: The Example of Prof. Dr. Ahmet Taner Kışlalı Neighborhood in Çayyolu/Ankara

    Directory of Open Access Journals (Sweden)

    Ahmet Tanju Gültekin

    2015-12-01

    Full Text Available Since 1980, the dynamics of globalization have directed the processes of social, cultural, and political adjustment as well as those of economic integration and especially capital towards urban development, forming urban space. The wave of globalization in Turkey, within a process of economic change in the context of neo liberal policies, urban space has been turned into the most profitable area of investment in the unearned income (economic rent sector. The residential sector has been included in this process quickly and easily through effective and widespread marketing strategies. Over the last two decades of this development, the Ankara-Çayyolu District has become segregated economically and socially between its upper and upper-middle class residents in the urban context. This segregation is evident in residential areas with high-level physical and spatial quality. On the other hand, in addition to the measurable physical and spatial standards of housing quality, it is also important to find out if the quality of living meets the social and cultural expectations of its residents. Starting from this point of view, we examine residents’ perceptions of their physical and social environment in our chosen sample area in the Prof. Dr. Ahmet Taner Kışlalı Neighborhood, and their demands and awareness of housing quality. The story of this neighborhood, which begins in 1980, at a time when neo liberal policies and the power to form urban space was all-important, is defined here by the residents’ quality of living and awareness of it. Our results obtained are expected to help guide the creation of liveable housing areas in the future.Keywords: Housing Users, Urban Living Quality, Social Living, Awareness, Ankara- Çayyolu-Prof. Dr. Ahmet Taner Kışlalı Neighborhood.

  15. Horas de sono e índice de massa corporal em pré-escolares do sul do Brasil

    Directory of Open Access Journals (Sweden)

    Maria Laura da Costa Louzada

    2012-12-01

    Full Text Available A prevenção e o tratamento do excesso de peso são particularmente complexos, reforçando a importância de estudos que visem esclarecer sua rede de causas e efeitos. Assim, o objetivo desse estudo foi avaliar a relação entre horas de sono noturnas e medidas antropométricas. Realizou-se uma análise transversal realizada a partir de dados de 348 crianças de 3 e 4 anos da cidade de São Leopoldo/ RS. As horas de sono noturnas foram relatadas pelas mães e as medidas de índice de massa corporal, circunferência da cintura e dobras cutâneas foram medidas de acordo com protocolo padrão. As análises foram ajustadas para consumo energético e horas de televisão assistidas. As crianças com excesso de peso apresentaram, em média, 0,39 horas a menos de sono em relação àquelas com peso adequado (9,77 ± 1,44 versus 10,17 ± 1,34; IC95% 0,03-0,76. Observou-se associação inversa entre horas de sono noturnas e valores de escore z de índice de massa corporal para idade (B = -0,12 IC95% -0,22--0,02. A circunferência da cintura e as dobras cutâneas apresentaram relação inversa com as horas de sono, porém sem diferença estatística. Em pré-escolares do sul do Brasil, menos horas de sono noturnas foram associadas com maiores valores de índice de massa corporal.

  16. The design of the covers of Zero Hora newspaper from 1990 to 2010

    Directory of Open Access Journals (Sweden)

    Ana Gruszynski

    2011-06-01

    Full Text Available The article investigates the reformulations of the graphic presentation undergone by the Zero Hora (ZH newspaper from 1990 to 2010, focusing on its covers. It analyzes how this publication revamped its design in this period, in order to discuss how such changes could be related to technological changes pertaining to the circulation of editions in other media as well. It questions relationships between visual elements and principles of journalistic editing, considering the history of the vehicle. The significant change in the layouts perceived in the years taken into consideration seems to be associated with the growing amount of information available in the graphic space that is permeated by the intense usage of graphic resources and images that often undermine the hierarchy of what is being reported.

  17. THE DESIGN OF THE COVERS OF ZERO HORA NEWSPAPER FROM 1990 TO 2010

    Directory of Open Access Journals (Sweden)

    Ana Gruszynski

    2011-06-01

    Full Text Available The article investigates the reformulations of the graphic presentation undergone by the Zero Hora (ZH newspaper from 1990 to 2010, focusing on its covers. It analyzes how this publication revamped its design in this period, in order to discuss how such changes could be related to technological changes pertaining to the circulation of editions in other media as well. It questions relationships between visual elements and principles of journalistic editing, considering the history of the vehicle. The significant change in the layouts perceived in the years taken into consideration seems to be associated with the growing amount of information available in the graphic space that is permeated by the intense usage of graphic resources and images that often undermine the hierarchy of what is being reported.

  18. La última obra de Virginia Woolf: Las horas, de Stephen Daldry

    Directory of Open Access Journals (Sweden)

    María del Mar Paúl Arranz

    2007-05-01

    Full Text Available Dado el vínculo que entre la literatura y el cine, se discute la pertinencia de ciertos métodos de análisis en el tratamiento que ha dado el cine a los textos literarios. La película Las horas (2003 se presenta como una muestra de un diálogo creativo no sólo con la novela de Michel Cunningham de la que parte, sino con la obra literaria de Virginia Woolf, que está en la base de ambas. La película nos invita a replantearnos aspectos de la condición humana otorgando a las mujeres un absoluto e insólito protagonismo.

  19. Adaptabilidade do tempo de trabalho, banco de horas e horário concentrado

    OpenAIRE

    Verdasca, Daniela Vieira

    2017-01-01

    No presente trabalho pretendemos analisar os regimes de adaptabilidade, banco de horas e horário concentrado, bem como ponderar a sua contribuição para os princípios sempre presentes na temática da duração do trabalho, que por vezes se revelam antagónicos: a proteção do trabalhador, a tutela da sua saúde e da sua vida familiar e pessoal, uma vez que estes mecanismos permitem a variação do tempo de trabalho e logo dos tempos de não trabalho, e a salvaguarda dos interesses de gestão, sendo que ...

  20. Fadiga e capacidade para o trabalho em turnos fixos de doze horas

    Directory of Open Access Journals (Sweden)

    Metzner Ricardo Jorge

    2001-01-01

    Full Text Available OBJETIVO: Analisar as variáveis que interferem na percepção de fadiga e na capacidade para o trabalho em trabalhadores que executam suas atividades em turnos fixos diurnos e noturnos. MÉTODOS: Estudo transversal, com participação de 43 trabalhadores de turnos diurnos e noturnos de uma indústria têxtil, que trabalhavam em turnos fixos de 12 horas diárias e semana reduzida. Mediante vários questionários, o grupo estudado respondeu a questões sobre: fadiga, índice de capacidade para o trabalho, características individuais, estilos de vida e condições de trabalho. Foi feita análise de regressão linear univariada. RESULTADOS: Os fatores que influenciaram a percepção de fadiga associam-se a estilos de vida dos trabalhadores (a prática de exercício físico é um fator protetor e à dificuldade em manter o sono, que, se presente, aumenta a percepção de fadiga. Os fatores associados à percepção do índice de capacidade para o trabalho (ICT foram o tempo de exercício na função e o turno noturno de trabalho: quanto maior o primeiro, menor o ICT; trabalhar à noite aumenta o ICT. A duração da jornada diária de 12 horas pode provocar aumento considerável na carga de trabalho, influenciando a percepção do trabalhador sobre a capacidade para o trabalho, a fadiga e as alterações do sono. CONCLUSÕES: Os resultados indicam que nem sempre o trabalho noturno mostra-se como fator prejudicial à saúde. Entretanto, a amostra estudada é pequena, o estudo é transversal, e pode ter ocorrido um efeito de seleção. Assim, é necessária a realização de estudos longitudinais, com amostras maiores, dado que o ICT tende a diminuir à medida que aumenta o tempo na função.

  1. Asociación entre horas de televisión, actividad física, horas de sueño y exceso de peso en población adulta joven

    Directory of Open Access Journals (Sweden)

    María Martínez-Moyá

    2014-05-01

    Conclusiones: Más horas de televisión y una menor actividad física se asociaron significativamente con un aumento del IMC en la población universitaria estudiada. Ambos factores pueden modificarse con estrategias preventivas.

  2. FINANÇAS COMPORTAMENTAIS: FATORES QUE INFLUENCIAM OS CONSUMIDORES NA HORA DA COMPRA

    Directory of Open Access Journals (Sweden)

    Wenner Glaucio Lopes Lucena

    2011-07-01

    Full Text Available Este trabalho objetiva estabelecer as principais influências comportamentais dos consumidores na hora da compra nas lojas da cidade de Caruaru-PE. A pesquisa foi realizada com consumidores da cidade de Caruaru-PE, no North Shopping, antigo Shopping Caruaru, e no centro da cidade. A amostra dessa pesquisa foram 200 consumidores. Apresentando os seguintes resultados: 50% do público declaram ser o preço o fator determinante ao escolher um produto, quando a qualidade do produto não está em questão. No que diz respeito a satisfazer as necessidades de auto-estima, o status da marca é fator decisivo de influência, com 23% das opiniões. Pela pesquisa aplicada, constata-se que, com 31% do total, o sábado é o dia preferido para fazer compras, pela maior disponibilidade de tempo, de produtos ofertados, quer seja no comércio, nas feiras livres ou nos shoppings da cidade. E há a possibilidade de contar com companhia de terceiros, tornando o ato do consumo mais atrativo. Diante de tudo que foi estudado e analisado nesta pesquisa, concluí-se que o comportamento do consumidor deve ser estudado por todos que ofertem algum produto ou serviço. Uma vez que o mesmo é determinante na decisão de compra e no sucesso de uma empresa.

  3. A partilha do trabalho e a demanda dinâmica por trabalhadores e horas

    Directory of Open Access Journals (Sweden)

    Rodrigo Pereira

    2001-03-01

    Full Text Available Este artigo investiga se uma redução na jornada de trabalho padrão tem um impacto positivo sobre o nível de emprego, um efeito conhecido na literatura como partilha do trabalho (work-sharing. A inovação do artigo consiste na inclusão de custos de ajustamento do emprego no modelo teórico, o que introduz interessantes aspectos dinâmicos que permitem estudar as trajetórias ótimas do emprego e das horas médias no curto e longo prazos. A principal conclusão é que a partilha do trabalho não ocorre, mesmo considerando os custos de ajustamento do emprego.This paper investigates whether a reduction in standard hours has a positive impact on the employment level, an effect known in the literature as work-sharing. The innovation here is to include employment adjustment costs in the theoretical model. This feature introduces interesting dynamic aspects, which make it possible to study optimal paths of employment and average hours both in the short and the long run. The main result is that work-sharing does not occur even in the presence of employment adjustment costs.

  4. Hop Resistance in the Beer Spoilage Bacterium Lactobacillus brevis Is Mediated by the ATP-Binding Cassette Multidrug Transporter HorA

    OpenAIRE

    Sakamoto, Kanta; Margolles, Abelardo; van Veen, Hendrik W.; Konings, Wil N.

    2001-01-01

    Lactobacillus brevis is a major contaminant of spoiled beer. The organism can grow in beer in spite of the presence of antibacterial hop compounds that give the beer a bitter taste. The hop resistance in L. brevis is, at least in part, dependent on the expression of the horA gene. The deduced amino acid sequence of HorA is 53% identical to that of LmrA, an ATP-binding cassette multidrug transporter in Lactococcus lactis. To study the role of HorA in hop resistance, HorA was functionally expre...

  5. A HORA DA ESTRELA: UMA BIOGRAFIA (AUTO FICCIONAL DE CLARICE LISPECTOR

    Directory of Open Access Journals (Sweden)

    Carlos Vinícius Figueiredo (IFMS

    2013-10-01

    Full Text Available Por meio da trajetória de uma nordestina vivendo no Rio de Janeiro, a autora Clarice Lispector, utilizando-se da voz de um narrador homem, que também é um escritor, reflete sobre questões de escrita, sobre o contexto cultural de nosso país, descortinando assim suas raízes. Sob a esteira de pesquisadores como Nolasco, Souza e Klinger que amparam nossa reflexão sobre os estudos biográficos, objetivamos com este artigo apontar que A hora da estrela (1977 constitui a biografia intelectual da ficcionista Clarice Lispector. Dessa forma, é por meio da escrita biográfica que a ficção produz a vida de um escritor ou permite que esta seja relida na ficção. E os traços biográficos que constituem a vida do escritor são de extrema importância, devendo ser tomados como parte desse conjunto que redesenha vida e obra. PALAVRAS-CHAVE: Lispector; intelectual; biografia. Abstract Through the trajectory of a northeastern living in Rio de Janeiro, the writer Clarice Lispector, using the voice of a narrator, who is also a writer, reflects on issues written about the cultural context of our country, revealing her roots. Based on researchers as Nolasco, Souza and Klinger that support our reflection on the biographical studies, we aimed to point out in this article that The Hour of the Star (1977 is the intellectual biography of the writer Clarice Lispector. In this way, it is through writing biographical fiction that makes the life of a writer or allows it to be reread in fiction. And the biographical traits that constitute the writer's life are extremely important and should be taken as part of this set that redraws life and work.KEYWORDS: Lispector. Intellectual. Biography.

  6. Rearquitetura e informação 24 horas no IPA Metodista

    Directory of Open Access Journals (Sweden)

    Samile Andréa de Souza Vanz

    2007-04-01

    Full Text Available As bibliotecas universitárias vêm passando por mudanças há algumas décadas para acompanhar as alterações causadas pelas tecnologias disponíveis na sociedade atual. O ambiente físico da biblioteca é alvo de muitas destas mudanças, já que a informação, contida nas coleções de livros e periódicos, vem sendo transferida para acervos digitais, diminuindo a demanda por espaço físico e pelo contato bibliotecário-usuário, provocando alterações nos hábitos e cultura da comunidade universitária. Neste contexto, foi inaugurada em Porto Alegre a Biblioteca Central do IPA Metodista. O prédio, erguido no início do século passado, foi reformado para atender 24 horas, durante todo o ano. Apresentam-se aqui considerações acerca de layout, mobiliário, sinalização, iluminação, temperatura e preservação do acervo, e como isso foi pensado ao longo da reforma de um edifício destinado a funcionar ininterruptamente. Relata-se também o processo de adequação dos funcionários e do usuário ao horário integral da Biblioteca Central.

  7. Finanças comportamentais: fatores que influenciam os consumidores na hora da compra

    Directory of Open Access Journals (Sweden)

    Simone Pereira da Silva

    2011-01-01

    Full Text Available Este trabalho objetiva estabelecer as principais influências comportamentais dos consumidores na hora da compra em lojas da cidade de Caruaru-PE. A pesquisa foi realizada com consumidores da cidade de Caruaru-PE, no North Shopping, antigo Shopping Caruaru, e no centro da cidade. A amostra dessa pesquisa foi de 200 consumidores, apresentando os seguintes resultados: 50% do público declara ser o preço o fator determinante ao escolher um produto, quando a qualidade do produto não está em questão. No que diz respeito a satisfazer as necessidades de auto-estima, o status da marca é fator decisivo de influência, com 23% das opiniões. Pela pesquisa aplicada, constata-se que, com 31% do total, o sábado é o dia preferido para fazer compras, pela maior disponibilidade de tempo, de produtos ofertados, quer seja no comércio, nas feiras livres ou nos shoppings da cidade. E há a possibilidade de contar com companhia de terceiros, tornando o ato do consumo mais atrativo. Diante de tudo que foi estudado e analisado nesta pesquisa, concluí-se que o comportamento do consumidor deve ser estudado por todos que ofertem algum produto ou serviço, uma vez que o mesmo é determinante na decisão de compra e no sucesso de uma empresa.Abstract This work aims to establish the main influences consumer behavior when buying from stores across the city of Caruaru-PE. The survey was conducted with consumers of the city of Caruaru-PE, North Mall, Shopping Caruaru old, and in the city center. The sample of this study was 200 consumers, with the following results: 50% of the public claims to be the price the determining factor when choosing a product, where product quality is not an issue. Regarding the needs of self-esteem, status of the brand is a decisive factor of influence, with 23% of reviews. For applied research, it appears that, with 31% of the total, Saturday is the favorite day to shop, the greater availability of time, products offered, whether in trade

  8. Avaliação da função renal do idoso em duas horas

    OpenAIRE

    Benarab,Maria do Carmo B. Sammartino; Castiglia,Yara Marcondes Machado; Vianna,Pedro Thadeu Galvão; Braz,José Reinaldo Cerqueira

    2005-01-01

    JUSTIFICATIVA E OBJETIVOS: Os idosos têm diminuição progressiva da função renal e os hipertensos, maior risco de lesão renal adicional no intra-operatório. Avalia-se a função renal pela depuração da creatinina, com débito urinário de 24 horas, para diluir o erro de possível volume vesical residual (VVR). O objetivo deste trabalho foi avaliar a função renal pré-operatória de idosos hipertensos e não-hipertensos, com débito urinário de duas horas, utilizando aparelho de ultra-som portátil para ...

  9. Asma aguda em adultos na sala de emergência: o manejo clínico na primeira hora

    Directory of Open Access Journals (Sweden)

    DALCIN PAULO DE TARSO ROTH

    2000-01-01

    Full Text Available Asma é doença com alta prevalência em nosso meio e ao redor do mundo. Embora novas opções terapêuticas tenham sido recentemente desenvolvidas, parece haver aumento mundial na sua morbidade e mortalidade. Em muitas instituições, as exacerbações asmáticas ainda constituem emergência médica muito comum. As evidências têm demonstrado que a primeira hora no manejo da asma aguda na sala de emergência concentra decisões cruciais que podem determinar o desfecho desta situação clínica. Nesta revisão não-sistemática, os autores enfocaram a primeira hora da avaliação e tratamento do paciente com asma aguda na sala de emergência, descrevendo uma estratégia apropriada para o seu manejo. São consideradas as seguintes etapas: diagnóstico, avaliação da gravidade, tratamento farmacológico, avaliação das complicações e decisão sobre onde se realizará o tratamento adicional. Espera-se que estas recomendações contribuam para que o médico clínico tome a decisão apropriada na primeira hora do manejo da asma aguda.

  10. Hop resistance in the beer spoilage bacterium Lactobacillus brevis is mediated by the ATP-binding cassette multidrug transporter HorA.

    Science.gov (United States)

    Sakamoto, K; Margolles, A; van Veen, H W; Konings, W N

    2001-09-01

    Lactobacillus brevis is a major contaminant of spoiled beer. The organism can grow in beer in spite of the presence of antibacterial hop compounds that give the beer a bitter taste. The hop resistance in L. brevis is, at least in part, dependent on the expression of the horA gene. The deduced amino acid sequence of HorA is 53% identical to that of LmrA, an ATP-binding cassette multidrug transporter in Lactococcus lactis. To study the role of HorA in hop resistance, HorA was functionally expressed in L. lactis as a hexa-histidine-tagged protein using the nisin-controlled gene expression system. HorA expression increased the resistance of L. lactis to hop compounds and cytotoxic drugs. Drug transport studies with L. lactis cells and membrane vesicles and with proteoliposomes containing purified HorA protein identified HorA as a new member of the ABC family of multidrug transporters.

  11. Estudo comparativo entre o xenodiagnóstico artificial realizado imediatamente e quatro horas após a coleta de sangue

    OpenAIRE

    Castro,Cleudson; Santos,Martinho Candido A.; Silveira,Celeste Aida

    2004-01-01

    Foi realizado xenodiagnóstico artificial, imediatamente e quatro horas após a coleta do sangue, em 63 pacientes, sendo 29 (46%) do sexo masculino e 34 (54%) do sexo feminino. A idade mínima foi 18 anos e a máxima 68, sendo a idade média 39 anos. Onze (17,5%) pacientes apresentaram resultados positivos, sendo 8 (12,7%) no exame imediato e 7 (11,1%) no exame 4 horas após. Os oito pacientes do exame imediato apresentaram 17 pools positivos e os sete do xenodiagnóstico de quatro horas mostraram 1...

  12. Nueva formula matemática para el calculo de la proteinuria de 24 horas en niños

    Directory of Open Access Journals (Sweden)

    José R. Salabarría

    1996-08-01

    Full Text Available Se elaboró una fórmula matemática para la cuantificación de la excreción urinaria de proteínas en 24 horas en niños y adolescentes, derivada de la relación proteinuria creatinuria (RPC. Se procesaron 104 muestras de orina de 24 horas, las cuales se dividieron en 2 grupos de acuerdo con la excreción diaria de creatinina. La proteinuria de 24 horas se determinó en cada grupo por el método tradicional y mediante la fórmula propuesta. Se obtuvo una excelente correlación (r = 0,994 y una elevada concordancia en el grupo con recolecciones adecuadas de orina, no así en el grupo con recolecciones inadecuadas (r = 0,896. Al comparar las RPC en 30 muestras de orina obtenidas en 3 diferentes períodos, con la RPC de 24 horas correspondiente se obtuvo una elevada correlación (r 0,99; no obstante la que guardó mayor identidad fue la del período comprendido entre las 7:00 a.m. y 12:00 m.A mathematical formula for the quantification of 24-hour urinary protein excretion in children and adolescents, derived from the proteinuria-creatinuria relation (PCR was elaborated. 104 urine specimens were processed and divided into two groups according to daily creatinine excretion. 24-hour proteinuria was determined in each group by the traditional method and by the formula proposed. An excelent correlation (r=0,994 and an elevated correspondence in the group with adequate urine collections were obtained, but it was not so in the group with inadequate collections (r=0,896. On comparing the PCR in 30 urine specimens collected at three different periods with the corresponding 24-hour PCR, an elevated correlation (r 0,99 was obtained; however, the one with the greatest identity was that collected between 7:00 a.m. and 12:00 m.

  13. Dos Nuevas Técnicas Manuales Rápidas para Antibiogramas Urinarios en 6 a 18 horas

    Directory of Open Access Journals (Sweden)

    Margaret Ordóñez Smith de Danies

    1994-03-01

    Full Text Available

    Se estudiaron 694 muestras de orina de las cuales 130 sirvieron para estudiar dos nuevas técnicas manuales para antibiogramas urinarios con orinas de recuentos bacterianos >100.000 UCF/mL. Una se denomina NUEVA TECNICA DIRECTA, y se interpreta después de 6 a 18 horas de recolectada la muestra de orina, teniendo una confiabilidad del 99%. La segunda técnica se titula TECNICA DE ENRIQUECIMIENTO cuyo resultado se da entre 10 a 22 horas con una confiabilidad del 99% (p>0.900 en relación con las lecturas de la técnica estándar de difusión en disco. Con las nuevas técnicas no es necesario esperar al aislamiento bacteriano.

    Introducción
    Hasta donde llega mi conocimiento es la primera vez que se describen estas nuevas técnicas manuales para antibiogramas urinarios (se realizaron dos para escoger la mejor y obtener su informe rápido (6 a 18 horas. Al comparar las nuevas técnicas descritas con la técnica estándar de difusión en disco se ahorran de 30 a 40 horas, y el costo del cultivo para el aislamiento bacteriano. Las técnicas que propongo están al alcance económico de todo laboratorio, en especial para los países en donde no tengan equipos sistematizados, por su alto costo. Estas nuevas técnicas son totalmente manuales y además para el paciente tienen la ventaja de que le formulen pronto y a ciencia cierta el antibiótico más eficaz. Nuestras nuevas técnicas sólo se pueden aplicar para recuentos >100.000 UCF/mL, aunque hoy en día los criterios de infección urinaria no son de recuentos tan altos (1, 2, 3, 4,5...

  14. Hiperoxia por dos horas produce daño morfológico cerebral luego de asfixia neonatal experimental

    Directory of Open Access Journals (Sweden)

    Melva Benavides

    2013-10-01

    Full Text Available Objetivos: Determinar el efecto de una exposición de dos horas de hiperoxia al 21%, 40% y 100% sobre la morfología cerebral, en un modelo experimental de asfixia neonatal. Diseño: Estudio experimental. Institución: Instituto Nacional de Salud del Niño, Lima, Perú. Material biológico: Ratas albinas Holtzmann. Intervenciones: Ciento veinte ratas albinas Holtzmann de una semana de nacidas (a excepción del grupo control fueron sometidas a asfixia experimental por ligadura de la arteria carótida izquierda y luego expuestas a hipoxia (oxígeno al 8%. Después fueron asignadas aleatoriamente a uno de los siguientes grupos: exposición por dos horas a O2 al 100%, a O2 al 40%, a O2 al 21% y un grupo control (no expuesto a asfixia experimental. El daño cerebral fue evaluado mediante la medición del peso cerebral y el porcentaje del área cerebral con daño microscópico. Principales medidas de resultados: Daño cerebral. Resultados: El peso cerebral promedio fue menor en los animales de los grupos sometidos a hiperoxia experimental (ANOVA; p<0,001. Se presentó daño cerebral microscópico con mayor frecuencia en el grupo sometido a hipoxia experimental que recibió O2 100% por dos horas y con menor frecuencia en el que recibió O2 al 40% (60% versus 43,3%, diferencia que fue estadísticamente significativa (prueba χ²; p<0,001. El grupo sometido a hipoxia experimental que recibió O2 100% tuvo un mayor porcentaje promedio de área cerebral con daño microscópico (18,3%, en comparación con los otros grupos de hipoxia experimental, aunque la diferencia no fue estadísticamente significativa (ANOVA; p=0,123. Conclusiones: La hiperoxia al 100% por dos horas se asoció con menor peso cerebral y mayor daño cerebral en animales de experimentación sometidos a asfixia neonatal experimental.

  15. La iluminación de Macabea: el fracaso del narrador en La hora de la estrella, de Clarice Lispector

    Directory of Open Access Journals (Sweden)

    Kevin Andrés Pérez Méndez

    2016-08-01

    Full Text Available Este ensayo analiza la problemática presente en la narrativa de Clarice Lispector, específicamente en su novela La hora de la estrella (1977, respecto de los modos de hacer ficción y de organizar las instancias narrativas en una historia. El autor pretende mostrar cómo en La hora de la estrella se articulan mecanismos que desestabilizan la norma tradicional de construir un relato, mostrando, en este caso, los límites que la voz narrativa padece en su deber de idear y exponer lo que constituye el argumento de la novela, así como el surgimiento de lo que se puede denominar como una voz alternativa de enunciación. El articulo, por lo tanto, también indaga la presencia y la disposición de ciertos obstáculos que, a modo de amenazas, ponen en crisis la autoridad de la narración y destruyen el orden establecido entre quien subordina y quienes son subordinados dentro del texto.

  16. Promoter Engineering Reveals the Importance of Heptameric Direct Repeats for DNA Binding by Streptomyces Antibiotic Regulatory Protein-Large ATP-Binding Regulator of the LuxR Family (SARP-LAL) Regulators in Streptomyces natalensis.

    Science.gov (United States)

    Barreales, Eva G; Vicente, Cláudia M; de Pedro, Antonio; Santos-Aberturas, Javier; Aparicio, Jesús F

    2018-05-15

    The biosynthesis of small-size polyene macrolides is ultimately controlled by a couple of transcriptional regulators that act in a hierarchical way. A Streptomyces antibiotic regulatory protein-large ATP-binding regulator of the LuxR family (SARP-LAL) regulator binds the promoter of a PAS-LuxR regulator-encoding gene and activates its transcription, and in turn, the gene product of the latter activates transcription from various promoters of the polyene gene cluster directly. The primary operator of PimR, the archetype of SARP-LAL regulators, contains three heptameric direct repeats separated by four-nucleotide spacers, but the regulator can also bind a secondary operator with only two direct repeats separated by a 3-nucleotide spacer, both located in the promoter region of its unique target gene, pimM A similar arrangement of operators has been identified for PimR counterparts encoded by gene clusters for different antifungal secondary metabolites, including not only polyene macrolides but peptidyl nucleosides, phoslactomycins, or cycloheximide. Here, we used promoter engineering and quantitative transcriptional analyses to determine the contributions of the different heptameric repeats to transcriptional activation and final polyene production. Optimized promoters have thus been developed. Deletion studies and electrophoretic mobility assays were used for the definition of DNA-binding boxes formed by 22-nucleotide sequences comprising two conserved heptameric direct repeats separated by four-nucleotide less conserved spacers. The cooperative binding of PimR SARP appears to be the mechanism involved in the binding of regulator monomers to operators, and at least two protein monomers are required for efficient binding. IMPORTANCE Here, we have shown that a modulation of the production of the antifungal pimaricin in Streptomyces natalensis can be accomplished via promoter engineering of the PAS-LuxR transcriptional activator pimM The expression of this gene is

  17. Behavioural Public Policy - vejen til en sundere kommune

    OpenAIRE

    Lützen, Daniel; Tejnø, Cecilie; Bastiansen, Pernille

    2014-01-01

    Abstract This project looks at how the health care policies of Holbæk municipality can be structured based on the theoretical framework of Behavioural Economics and Behavioural Public Policy, in order to minimise the effects of “high risk behaviour”. By focusing on two specific policy frameworks, namely 1) ensuring a healthy approach to food for children, young people and vulnerable citizens and 2) a smoke and alcohol free environment for children and young people, we attempt to ascertain, ba...

  18. Vi kan 'nudge' os til en sundere hverdag

    DEFF Research Database (Denmark)

    Hansen, Pelle Guldborg

    2013-01-01

    Viden er ikke altid tilstrækkelig til at ændre vores adfærd. Det er det voksende problem med livsstilssygdomme et bevis på. Heldigvis har adfærdsforskere fundet en billig lødsning som ved hjælp af psykologiske mekanismer får os til at handle til gavn for vores helbred....

  19. Inseminación artificial a tiempo fijo en vacas con proestro prolongado de 60 y 72 horas

    Directory of Open Access Journals (Sweden)

    Darwin Omar Yánez-Avalos

    2018-05-01

    Full Text Available La inseminación artificial a tiempo fijo (IATF en ganado bovino ha permitido el uso de toros genéticamente superiores para maximizar la calidad de los terneros producidos. Sin embargo, la implementación de esta técnica reproductiva dificulta su aplicación en hembras bovinas que están con cría al pie durante varios meses de lactancia. Una solución inmediata a la disminución de la fertilidad en vacas incluye la utilización de hormonas. Se ha desarrollado una serie de tratamientos hormonales que es capaz de controlar el momento de la primera inseminación artificial (IA y las inseminaciones posteriores en vacas no preñadas y para el tratamiento de vacas en anestro. El objetivo de este trabajo fue evaluar dos protocolos con proestro prolongado con inseminación artificial a tiempo fijo (IATF a las 60 o 72 horas, en vacas doble propósito de la Amazonía Ecuatoriana. El trabajo se realizó desde octubre de 2015 a octubre de 2016. Se inseminaron 226 vacas multíparas cruzas Pardo Suizo con cría al pie, a las 60 (T1, n=115 y 72 (T2, n= 111 horas de retirado el dispositivo con progesterona (0,5g. La tasa de concepción para T1 fue del 61% (70/115 y para T2: el 47% de preñez (52/111, con diferencias significativas (p≤0,05. El celo en promedio fue de 70,8%, sin diferencia significativa entre tratamientos (P=3,15; p≥0,082, para T1 fue del 76% y para T2 del 65%. El crecimiento folicular al retiro del dispositivo con progesterona (T1: 9,53±0,11 mm; T2: 9,87± 0,12 mm, la IATF (T1: 12,3±0,12 mm; T2: 11,9±0,12 mm y el tamaño del cuerpo lúteo (T1: 23,1±0,14 mm; T2: 22,8± 0,15 mm, no mostraron diferencias significativas entre ambos protocolos (p≥0,05. Ambos tratamientos no mostraron diferencias significativas para el desarrollo folicular al momento del retiro del dispositivo de IATF y en el tamaño del cuerpo lúteo medido al día siete posterior a la misma. La tasa de preñez fue superior para el protocolo de 60 horas.

  20. Newspaper design – processes, routines and product: a study of Segundo Caderno, the Zero Hora cultural supplement

    Directory of Open Access Journals (Sweden)

    Patrícia Lopes Damasceno

    2014-06-01

    Full Text Available The article discusses the graphic design of Segundo Caderno supplement  from the newspaper Zero Hora (ZH. The study identifies and analyses witch graphical elements e what compositional strategies are used by the periodic, verifying how these area articulated with the editorial process and the values of the journalistic field. The methodological procedures utilized were bibliographical research; qualitative and quantitative evaluation of a corpus composed by 24 editions of the months of June, August, September and October of 2011; observation of the productive routines; and non-structured interviews with five professionals of this supplement. The results showed that journalism possesses a strong e consolidated work culture, and that its constraints guide the design practice in this context. It was also observed that the ignorance of the reader's profile by the journalists, the mismatch between the possibility of advanced planning in virtue of the connection with the events agenda and the restricted use of visual resources, highlighting by a significant number of released photos.

  1. Newspaper design – processes, routines and product: a study of Segundo Caderno, cultural supplement from Zero Hora

    Directory of Open Access Journals (Sweden)

    Ana Gruszynski

    2014-06-01

    Full Text Available The article discusses the graphic design of Segundo Caderno supplement  from the newspaper Zero Hora (ZH. The study identifies and analyses witch graphical elements e what compositional strategies are used by the periodic, verifying how these area articulated with the editorial process and the values of the journalistic field. The methodological procedures utilized were bibliographical research; qualitative and quantitative evaluation of a corpus composed by 24 editions of the months of June, August, September and October of 2011; observation of the productive routines; and non-structured interviews with five professionals of this supplement. The results showed that journalism possesses a strong e consolidated work culture, and that its constraints guide the design practice in this context. It was also observed that the ignorance of the reader's profile by the journalists, the mismatch between the possibility of advanced planning in virtue of the connection with the events agenda and the restricted use of visual resources, highlighting by a significant number of released photos.

  2. NEWSPAPER DESIGN – PROCESSES, ROUTINES AND PRODUCT: A STUDY OF SEGUNDO CADERNO, THE ZERO HORA CULTURAL SUPPLEMENT

    Directory of Open Access Journals (Sweden)

    Patrícia Lopes Damasceno

    2014-06-01

    Full Text Available The article discusses the graphic design of Segundo Caderno supplement  from the newspaper Zero Hora (ZH. The study identifies and analyses witch graphical elements e what compositional strategies are used by the periodic, verifying how these area articulated with the editorial process and the values of the journalistic field. The methodological procedures utilized were bibliographical research; qualitative and quantitative evaluation of a corpus composed by 24 editions of the months of June, August, September and October of 2011; observation of the productive routines; and non-structured interviews with five professionals of this supplement. The results showed that journalism possesses a strong e consolidated work culture, and that its constraints guide the design practice in this context. It was also observed that the ignorance of the reader's profile by the journalists, the mismatch between the possibility of advanced planning in virtue of the connection with the events agenda and the restricted use of visual resources, highlighting by a significant number of released photos. 

  3. Reflexões tardias sobre Pierrot Le Fouou lições de cinema com O Demônio das onze horas

    Directory of Open Access Journals (Sweden)

    Silva, João Guilherme Barone Reis e

    2001-01-01

    Full Text Available Vista de longe, a fila na porta do cinema era um grande plano geral. O luminoso em letras vermelhas, refletia o título do filme no asfalto molhado: O Demônio das Onze Horas - Godard

  4. Reflexões tardias sobre Pierrot Le Fouou lições de cinema com O Demônio das onze horas

    Directory of Open Access Journals (Sweden)

    Silva, João Guilherme Barone Reis e

    2001-01-01

    Full Text Available Vista de longe, a fila na porta do cinema era um grande plano geral. O luminoso em letras vermelhas, refletia o título do filme no asfalto molhado: O Demônio das Onze Horas - Godard.

  5. Hop resistance in the beer spoilage bacterium Lactobacillus brevis is mediated by the ATP-binding cassette multidrug transporter HorA

    NARCIS (Netherlands)

    Sakamoto, K; Margolles, A; van Veen, HW; Konings, WN

    Lactobacillus brevis is a major contaminant of spoiled beer. The organism can grow in beer in spite of the presence of antibacterial hop compounds that give the beer a bitter taste. The hop resistance in L. brevis is, at least in part, dependent on the expression of the horA gene. The deduced amino

  6. Utilidad de la recolección de orina de dos horas para el diagnóstico del tipo de acidosis tubular renal

    Directory of Open Access Journals (Sweden)

    Margarita Irene Rocha-Gómez

    2015-08-01

    Full Text Available La acidosis tubular renal se caracteriza por acidosis metabólica hiperclorémica. El diagnóstico del tipo de acidosis tubular renal se realiza mediante la medición del transporte tubular máximo de bicarbonato y de la capacidad de acidificación urinaria; sin embargo, estas pruebas son invasivas y requieren determinaciones especializadas. Objetivo: comparar la utilidad de la recolección urinaria de dos horas, una prueba relativamente simple y al alcance de muchos laboratorios, con la medición del transporte tubular máximo de bicarbonato y con la capacidad de acidificación urinaria (procedimientos de referencia para clasificar el tipo de acidosis tubular renal en pacientes pediátricos. Material y método: el estudio se realizó en niños con diagnóstico de acidosis tubular renal. El primer día se recolectó la muestra sérica y urinaria de dos horas. Al día siguiente se efectuaron los procedimientos de referencia administrando bicarbonato de sodio en 8 horas; las muestras se colectaron cada hora y se determinaron la reabsorción de bicarbonato y la acidificación urinaria.  Resultados: se incluyeron 19 pacientes y en 17 casos la colección urinaria de dos horas confirmó el diagnóstico de los procedimientos de referencia. La recolección urinaria de dos horas tuvo sensibilidad de 0.94 y especificidad de 0.67 para el diagnóstico de acidosis tubular renal distal. Conclusión: la recolección de orina de dos horas se realiza en forma menos invasiva y ofrece resultados semejantes a los procedimientos de referencia.

  7. Depressão e suicídio no filme "As Horas" Depresión y suicidio en la película "Las Horas" Depression and suicide in the movie "The Hours"

    Directory of Open Access Journals (Sweden)

    Maria Helena Moraes

    2006-04-01

    Full Text Available As histórias dramatizadas nas telas dos cinemas são impactantes, uma vez que suscitam sentimentos vivenciados pelos seus apreciadores. Nessa perspectiva, o presente artigo procura identificar, demonstrar e comentar o comportamento depressivo nos personagens do filme As horas, de Stephen Daldry. Os personagens ilustram a vivência e convivência de pessoas com quadros depressivos em diferentes épocas e em diferentes graus de morbidade. O filme procura mostrar as diferentes manifestações comportamentais e sintomáticas através da apresentação pessoal de cada personagem e também através do cenário das histórias representadas. Observam-se traços de depressão psicótica na personagem de Virginia Woolf e um estado depressivo que tende à distimia na personagem de Laura Brown. Clarissa sugere uma "depressão dissimulada" e fortemente relacionada a Richard, cuja depressão culmina em suicídio. A condensação de épocas e a interligação entre os personagens refletem a universalidade e a atemporalidade dos fenômenos psíquicos, embora vividos de forma particular por cada um dos personagens.Las historias dramatizadas en las pantallas de los cines son impactantes, una vez que suscitan sentimientos vivenciados por sus apreciadores. En esa perspectiva, el presente artículo busca identificar, demostrar y comentar el comportamiento depresivo en los personajes de la película Las horas, de Stephen Daldry. Los personajes ilustran la vivencia y convivencia de personas con cuadros depresivos en distintas épocas y en distintos grados de morbidad. La película busca mostrar las distintas manifestaciones comportamentales y sintomáticas a través de la presentación personal de cada personaje y también a través del escenario de las historias representadas. Se observan rasgos de depresión psicótica en el personaje de Virginia Woolf y un estado depresivo que tiende a la distimia en el personaje de Laura Brown. Clarisa sugiere una "depresi

  8. Pile oscillator measurements of thermal absorption cross sections of Al, Mg, Fe and Cu; Mesure des sections efficaces thermiques d'absorption de l'Al, du Mg, du Fe et du Cu par la methode d'oscillation

    Energy Technology Data Exchange (ETDEWEB)

    Carre, J C; Vidal, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    The phase oscillation technique used at ZOE has the property of reducing of a marked factor the effect of neutron scattering by the sample. The absorption cross sections of poorly absorbing and highly scattering materials have been measured; for neutrons of 2,200 m/s, the following values are obtained: 229 {+-} 3 mb for Al; 64.2 {+-} 1.5 mb for Mg, 2.53 {+-} 0.03 b for Fe and 3.74 {+-} 0.04 b for Cu. (authors) [French] La methode d'oscillation de phase utilisee a ZOE possede la propriete de diminuer d'un facteur important l'influence de la diffusion. Les sections efficaces de capture de materiaux peu capturants et tres diffusants, ont ete mesurees; pour des neutrons de 2200 m/s, on obtient pour l'Al: 229 {+-} 3mb, pour le Mg: 64,2 {+-} 1,5 mb, pour le Fe: 2,53 {+-} 0,03 b et pour le Cu: 3,74 {+-} 0,04 b. (auteurs)

  9. Os efeitos da redução da jornada de trabalho de 48 para 44 horas semanais em 1988

    Directory of Open Access Journals (Sweden)

    Gustavo M. Gonzaga

    2003-06-01

    Full Text Available A redução da jornada de trabalho de 44 para 40 horas semanais tem sido freqüentemente proposta pelas centrais sindicais como solução para a escassa geração de empregos no país. A idéia, conhecida como partilha do trabalho (work-sharing, é que a redução de jornada permitiria que o mesmo trabalho fosse repartido por mais trabalhadores. No entanto, a maior parte dos artigos contesta a base teórica e a observação empírica de ocorrência de partilha do trabalho. O objetivo deste artigo é estudar os efeitos da redução de jornada prescrita pela Constituição de 1988, de 48 para 44 horas por semana, sobre o mercado de trabalho no Brasil. Os resultados do exercício empírico mostram que as alterações da Constituição, referentes à jornada de trabalho, provocaram uma queda da jornada efetiva de trabalho, não aumentaram a probabilidade de o trabalhador afetado pela mudança ficar desempregado em 1989 (quando comparada a outros anos, diminuíram a probabilidade de o trabalhador afetado de ficar sem emprego em 1989 (o que inclui os que saíram da força de trabalho e implicaram um aumento do salário real horário (apesar de menor do que o observado para trabalhadores que reduziram a jornada em outros anos. Esses resultados indicam que, no curto prazo (nos 12 meses seguintes à mudança constitucional, a redução de jornada não teve efeitos negativos sobre o emprego.The reduction of standard weekly working time from the current level of 44 hours to 40 hours has recently been proposed by the main central unions as a way to create jobs and reduce unemployment in Brazil. The idea, known as work-sharing, is that the reduction in average hours per worker would allow the same tasks to be performed by more employees, a notion which has been challenged in the theoretical and empirical literature. The objective of this paper is to study the effects of the workweek reduction from 48 to 44 hours prescribed by the 1988 Constitution on the

  10. Propuesta de innovación a la hora de evaluar en la asignatura Modelos y Simulación

    Directory of Open Access Journals (Sweden)

    López, María Victoria

    2011-01-01

    Full Text Available La asignatura Modelos y Simulación pertenece al Plan de estudios de la Carrera de Licenciatura en Sistemas de Información, de la Facultad de Ciencias Exactas y Naturales y Agrimensura (Universidad Nacional del Nordeste. Esta asignatura nació con la puesta en marcha de la Carrera de Licenciatura en Sistemas (Plan anterior en el año 1988, y tuvo siempre el carácter de optativa, entre otras tres asignaturas. En este trabajo se sintetiza una propuesta de innovación a la hora de evaluar. El trabajo se compone de 4 secciones. En la sección 1 se caracteriza la asignatura objeto de estudio y se describe la modalidad de dictado actual. En la sección 2 se realiza una descripción de los instrumentos de evaluación empleados en la asignatura. En la sección 3 se analizan los mencionados instrumentos, desde las posturas de distintos autores en referencia a los enfoques de evaluación tradicionales y alternativos. Las estrategias de innovación alternativas propuestas para la asignatura son especificadas en la sección 4. En la sección 5 se describe una experiencia de implementación de la metodología de evaluación alternativa del portfolio. A modo de conclusión, afirmamos que la instancia de evaluación es un proceso que articula los objetivos propuestos, los contenidos abordados y las estrategias metodológicas utilizadas en la asignatura, integrando en un todo el proceso de enseñanza-aprendizaje.

  11. Jejum inferior a oito horas em cirurgias de urgência e emergência versus complicações

    Directory of Open Access Journals (Sweden)

    Adelita de Jesus Carvalho Martins

    2016-08-01

    Full Text Available RESUMO Objetivo: verificar a ocorrência de complicações intraoperatórias e pós-operatórias em pacientes submetidos a procedimentos cirúrgicos de urgência e emergência entre janeiro e dezembro de 2012, com tempo de jejum inferior a oito horas. Método: conduziu-se um estudo quantitativo, tipo coorte retrospectivo, por meio da análise de prontuários médicos. Resultados: foram incluídos 181 prontuários de pacientes submetidos a procedimentos cirúrgicos com duração média de 59,4 minutos, destacando-se a cirurgia de correção de fraturas em 32% dos casos. Foram observadas complicações em 36 (19,9% dos pacientes, destacando-se o vômito (47,2%; seguido de náuseas (16,7%; necessidade de transfusão sanguínea (13,9%; infecção do sítio cirúrgico (11,1%; e óbito (11,1%. O tempo médio de jejum foi de 133,5 minutos. O tempo de jejum não apresentou correlação estatisticamente significante com as complicações investigadas. Conclusão: as complicações intraoperatórias e pós-operatórias estiveram associadas às condições clínicas dos pacientes e não ao tempo de jejum.

  12. Jornada de horas reduzidas e equilíbrio trabalho e família no setor bancário.

    OpenAIRE

    Graciela Sanjutá Soares Faria

    2005-01-01

    Com as mudanças na organização do trabalho frente à emergência do sistema de produção flexível, especialmente a partir da década de 80, vêm se expandindo novos arranjos de trabalho, como por exemplo o trabalho de horas reduzidas, em que o número de horas trabalhadas por semana é menor que o padrão. Ao mesmo tempo, a participação feminina no mercado de trabalho se intensifica, sobretudo a partir da década de 70; por conseguinte, os conflitos entre trabalho e família tornam-se cada vez mais ...

  13. Porcentaje de horas de confort térmico con técnicas de enfriamiento evaporativo indirecto en techos estanque en clima árido

    Directory of Open Access Journals (Sweden)

    Luis Carlos Herrera

    2014-06-01

    Full Text Available En este documento se presenta un estudio comparativo del porcentaje de tiempo en que la temperatura operativa se ubica dentro de los límites de la zona de confort propuesta por la norma ASHRAE 55-2010 para edificios libremente ventilados. Las temperaturas estudiadas se registraron al interior de módulos experimentales con techo estanque, emplazados en clima cálido seco, a los que les fueron aplicadas cinco técnicas de enfriamiento pasivo. El experimento se llevó a cabo en Chihuahua, México (Lat.: 28N, Long.: 106W, altura: 1.425m durante el verano de 2012. Los resultados indican que el techo estanque es una excelente alternativa para incrementar el porcentaje de horas de confort, pues se alcanza hasta un 30% más horas en promedio, respecto de un módulo control sin techo estanque. Si se añade enfriamiento radiativo nocturno, el porcentaje aumenta a 40%, e incorporando masa térmica, se incrementa hasta en un 65%. Incluso, en algunos casos, el enfriamiento es tan intenso que se sobrepasa el rango inferior de confort en horas de las mañanas.

  14. The role of batak tobanese women as parrengge-rengge to enhance the living standards of family at Pajak Horas in Pematang Siantar city

    Science.gov (United States)

    Nurjannah; Dewi, R.

    2018-03-01

    This research aims to find out the role of Batak Tobanese Women as Parrengge-rengge (trading with small capital) to enhance the living standards of the family; an overview of the trading conducted by Parrengge-rengge and of the social relationships of Batak Tobanese women as parrengge-rengge at Pajak Horas in Pematang Siantar City. From the data resulted from the field research, it was found that the factor that encouraged Batak Tobanese women to be Parrengge-rengge is the economic pressure to improve family income, the work requirements of the informal sector that are relatively moderate and easy compared by the formal one, and their low educational background. Parrengge-rengge at Pajak Horas market in Pematang Siantar City plays dual roles; namely as Mother and traders. Batak Tobanese women play double jobs as parrengge-rengge because of economic pressure to improve their living standards and family income. They cannot do this job all the time for some reasons. Sometimes, they have to stop working for a while. Many reasons make them quit from “marrengge-rengge” such as running out of capital, getting older or some other reasons that cause them not to be able to keep working as Parrengge-rengge at Pajak Horas in Pematang Siantar City.

  15. Deterioro cognitivo y horas de sueño en mayores de 65 años no institucionalizados: estudio en farmacia comunitaria

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    Climent MT

    2015-06-01

    Full Text Available Objetivo: Determinar factores de riesgo, relacionados con el estilo de vida, asociados con la presencia de deterioro cognitivo en personas mayores de 65 años. Método: Para ello se diseñó un estudio observacional transversal con personas mayores de 65 años no institucionalizadas mediante entrevista personal estructurada. El estudio se realizó en 14 farmacias de la Comunidad Valenciana desde marzo 2011 hasta marzo de 2013. Se utilizan como test de cribado el Short Portable Mental State Questionnaire (SPMSQ de Pfeiffer y el Mini-Mental State Examination (MMSE versión NORMACODERM de Blesa. Se definió deterioro cognitivo por SPMSQ ≥ 3 (para analfabetos ≥ 4 y/o MMSE ≤ 24. Resultados: Participaron en el estudio 729 personas. Se encontró que el 17,6% de los participantes (n = 128 presentaban resultados compatibles con deterioro cognitivo. Se determinó que dormir 9 o más horas diarias es causa o consecuencia y, por tanto, un factor de riesgo y/o de alarma en el desarrollo de deterioro cognitivo en personas mayores de 65 años. El ejercicio físico y pocas horas de sueño no obtuvo relación con el deterioro cognitivo. Conclusión: El cambio de hábitos de sueño en el anciano (pasar a dormir más horas es una señal de alerta para estudiar la presencia de un posible deterioro cognitivo.

  16. Ensaio clinico com Teclozan: 500mg no tratamento da colite amebiana não disentérica. (Resultados com esquema terapêutico de 24 horas

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    Donald Huggins

    1978-12-01

    Full Text Available O Autor relata sua experiência com novo esquema terapêutico com Teclozan - dose total de 1.500mg empregada em 24 horas, em 40 pacientes portadores de colite amebiana não disentérica na Disciplina de Doenças Infecciosas e Parasitárias da Universidade Federal de Pernambuco. Após um controle de cura realizado no 4º, 8º, 12º e 20º dias após o tratamento, obteve eficácia em 75% dos enfermos (30 casos e excelente tolerância.

  17. Da partilha do sensível no Brasil: uma leitura de \\'A hora e a vez de Augusto Matraga\\' e \\'Buriti\\'

    OpenAIRE

    Thaís Travassos

    2015-01-01

    Este trabalho propõe uma leitura dos aspectos estruturais de narração, construção de personagens e enredo a partir de uma perspectiva que os considera como dados essenciais para aquilo que Rancière (2004) chamou de política da literatura. Os textos escolhidos, A hora e a vez de Augusto Matraga, de Sagarana, e Buriti, de Corpo de baile, foram considerados dentro de uma tradição brasileira da fala sobre um outro cultural, presente desde os românticos até os modernos. Tentou-se compreender como ...

  18. Archeologický výzkum zaniklého těžebního areálu u kostela sv. Václava v Pněvicích (okr. Kutná Hora)

    Czech Academy of Sciences Publication Activity Database

    Končelová, Markéta; Velímský, Filip

    2012-01-01

    Roč. 12, prosinec (2012), s. 253-256 ISSN 1801-5972 Institutional research plan: CEZ:AV0Z80020508 Keywords : Kutná Hora * archaeology * Middle Ages * silver mining Subject RIV: AC - Archeology, Anthropology, Ethnology

  19. MANUAL JORNALÍSTICO E PRÁTICAS CONTRADITÓRIAS: DIÁLOGO ENTRE O TEXTO DE ZERO HORA E A TRAJETÓRIA DA RBS

    Directory of Open Access Journals (Sweden)

    Maria Berenice da Costa Machado

    2007-08-01

    Full Text Available Para bem refletir sobre um jornal, no caso Zero Hora (ZH, de Porto Alegre, seria necessário, também, resgatar a história da sua controladora, a Rede Brasil Sul (RBS. O exercício fez emergir muitas contradições entre o código normativo do diário e a trajetória do Grupo de comunicação. Oito desses episódios trazemos para o diálogo neste estudo: o uso indiscriminado de nomes e siglas, dos espaços de expressão das opiniões, os cruzamentos do jornalismo – editorial – com a publicidade – comercial –, os desencontros de datas, a estrutura monopolística, os valores propagados, a relação com as pessoas e a parceria com a Rede Globo. Nossa hipótese é de que está na gênese da RBS (e de ZH a “vocação” para o contraditório. PALAVRAS-CHAVE: Zero Hora. Rede Brasil Sul. História. Contradições.

  20. Menos horas de sueño asociado con sobrepeso y obesidad en estudiantes de nutrición de una universidad chilena

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    Samuel Durán-Agüero

    Full Text Available El objetivo del estudio fue determinar la asociación entre menor número de horas de sueño y sobrepeso/obesidad en estudiantes de nutrición de primero a cuarto año, de la Universidad San Sebastián en Chile. Se evaluaron 635 estudiantes, de los cuales el 86,4% fueron mujeres. A cada estudiante se aplicó la encuesta de sueño de Pittsburg, una evaluación antropométrica y se calculó el índice de masa corporal. Se realizaron análisis de regresión logística crudo y ajustado. El 57,1% de estudiantes duerme menos de lo recomendado. Dormir menos se asocia con sobrepeso u obesidad en el modelo ajustado por edad y somnolencia diurna (ORa: 1,84; IC 95%: 1,26-2,68 y ajustado por edad, consumo de tabaco, lácteos, frutas, verduras, leguminosas, somnolencia diurna (ORa: 1,83; IC 95%: 1,29-2,76. Existe asociación entre menos horas de sueño y mayor peso corporal en esta población, siendo un factor que considerar en la prevención de sobrepeso.

  1. A amamentação na primeira hora de vida e mortalidade neonatal Breastfeeding during the first hour of life and neonatal mortality

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    Cristiano Siqueira Boccolini

    2013-04-01

    Full Text Available OBJETIVO: Analisar a correlação entre o percentual de amamentação na primeira hora de vida e as taxas de mortalidade neonatal. MÉTODOS: Foram utilizados dados secundários de 67 países obtidos das pesquisas realizadas com a metodologia do Demographic and Health Surveys. Inicialmente, para a análise dos dados, foram empregadas a Correlação de Spearman (IC 95% e a análise gráfica com modificação de Kernel, seguidas de regressão de Poisson Binomial Negativa, ajustando para possíveis fatores de confundimento. RESULTADOS: O percentual de aleitamento materno na primeira hora de vida esteve negativamente associado com as taxas de mortalidade neonatal (Rho = -0,245, p = 0,046, e esta correlação foi mais forte entre os países com mortalidade neonatal superior a 29 mortes/1.000 nascidos vivos (Rho = -0,327, p = 0,048. Os países com os menores tercis de aleitamento materno na primeira hora de vida tiveram uma taxa 24% maior de mortalidade neonatal (razão de taxa = 1,24, IC 95% = 1,07-1,44, mesmo ajustando para fatores de confundimento. CONCLUSÃO: O efeito protetor da amamentação na primeira hora de vida sobre a mortalidade neonatal encontrado nesse estudo ecológico é consistente com o de estudos observacionais, e aponta para a importância de se adotar a amamentação na primeira hora de vida como prática de atenção neonatal.OBJECTIVE: To analyze the correlation between breastfeeding in the first hour of life with neonatal mortality rates. METHODS: The present study used secondary data from 67 countries, obtained from the Demographic and Health Surveys. Initially, for data analysis, Spearman Correlation (95% CI and Kernel graphical analysis were employed, followed by a Negative Binomial Poisson regression model, adjusted for potential confounders. RESULTS: Breastfeeding within the first hour of life was negatively correlated with neonatal mortality (Spearman's Rho = -0.245, p = 0.046, and this correlation was stronger among

  2. Adesão ao tratamento e controle da pressão arterial por meio da monitoração ambulatorial de 24 horas

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    Guilherme Brasil Grezzana

    2013-04-01

    Full Text Available FUNDAMENTO: A hipertensão arterial sistêmica (HAS é um importante fator de risco cardiovascular, no entanto os níveis de controle pressórico persistem inadequados. A avaliação da adesão ao tratamento anti-hipertensivo com a utilização da monitoração ambulatorial da pressão arterial (MAPA de 24 horas pode representar um importante auxílio na busca de metas de controle da HAS. OBJETIVO: Avaliar a adesão ao tratamento anti-hipertensivo e a sua relação com os valores de PA obtidos pela MAPA de 24 horas entre pacientes hipertensos de centros de atenção primária à saúde (APS. MÉTODOS: Estudo transversal com 143 pacientes hipertensos de amostra representativa de serviço de APS do município de Antônio Prado, RS. Foi realizada aplicação do teste de Morisky e Green para avaliar a aderência ao tratamento e a verificação do número de medicamentos utilizados, seguida pela aplicação da MAPA de 24 horas. RESULTADOS: Observou-se que 65,7% da amostra foram considerados aderentes ao tratamento proposto, 20,3% eram moderadamente aderentes, enquanto somente 14% foram classificados como não aderentes. Do total de 143 pacientes avaliados, 79 (55,2% foram identificados como HAS controlada (130/80 mmHg, 103 (72% apresentaram ausência de descenso noturno da PA e 60 (41,9% não estavam controlados durante o período de vigília. CONCLUSÃO: Verificamos, no presente estudo, que não há um controle adequado da HAS, com consequente perda de oportunidade dos profissionais envolvidos na APS de ajuste adequado das metas de PA preconizados. Esse fato ocorre a despeito de apropriada adesão ao tratamento anti-hipertensivo dos pacientes vinculados ao ambulatório de APS.

  3. Comportamiento de las lesiones por quemaduras atendidas antes de las 72 horas y después de dicho período

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    Mario Lozada Chinea

    Full Text Available Introducción: las quemaduras representan uno de los accidentes más graves e incapacitantes, son una de las condiciones más devastadoras encontradas en la medicina. Objetivo: comparar el comportamiento de las lesiones por quemaduras en pacientes que recibieron atención especializada en las primeras 72 horas y después de dicho período, en la consulta externa de quemados del Hospital Universitario "General Calixto García". Métodos: se realizó un estudio longitudinal prospectivo de serie de casos. El universo estuvo constituido por los pacientes atendidos ambulatoriamente y con pronóstico de vida leve y menos grave. Las series se dividieron en pacientes que recibieron tratamiento tardíamente: grupo I y pacientes que recibieron atención antes de las primeras 72 horas: grupo II. Resultados: el 43,88 % de los pacientes del grupo 1 recibieron la atención al cuarto día y el 42,77 % presentaron signos de infección local. El 53,88 % de los pacientes del mismo grupo 1 fueron remitidos por sus médicos de familia y el 37,22 % presentó profundización en las lesiones. En ambos grupos predominó el tratamiento antibiótico local de las lesiones. Los pacientes del grupo 1 tuvieron un promedio de 16,59 días para la epitelización total de las lesiones, superior al grupo 2, lo que conllevó a un mayor número de sesiones de cura. Conclusiones: la atención especializada de las lesiones por quemaduras después de las primeras 72 horas, aumenta las probabilidades de infección y profundización como principales complicaciones, lo que contribuye a un retardo en el proceso de cicatrización y de rehabilitación.

  4. La distinta naturaleza del día y la noche en la antigüedad, y sus divisiones en horas

    Directory of Open Access Journals (Sweden)

    Daniel Gil Martínez

    2012-06-01

    Full Text Available En este artículo intento explicar las diferencias religiosas entre el día y la noche, ya que los hombres de la Antigüedad nunca comprendieron que ambas conformaran una unidad. Estudio, por tanto, las características que tuvieron el día y la noche, en especial las de esta última, en algunas de las culturas más representativas de la Antigüedad –sumeria, babilónica, egipcia, hebrea, griega, romana y celta–. Así, podemos observar que básicamente todas ellas consideran el día como un momento de vida, mientras que la noche, a menudo, es entendida como muerte y maldad. Con todo ello, podemos comprender por qué el día no fue dividido en veinticuatro horas, sino en doce diurnas y doce nocturnas.

  5. El valor de la opinión en los noticieros televisivos chilenos de hoy el caso de 24 horas central de TVN

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    Jimena Maiz Sáenz-Villarreal

    2014-12-01

    Full Text Available Con la cultura de masas y como efecto de la búsqueda de consenso propia de la democracia, la opinión, entendida como juicio de valor, se ha incorporado en los noticieros televisivos como medio de legitimación para el líder que la emite y como forma de identificación para el receptor que se sienta representado por ella. Por ello, su intención es generar un acercamiento con el destinatario, tratando de impactar, al mismo tiempo, su inteligencia y sus emociones, para orientarlo en algún sentido a través de opiniones propiamente tales, expresión de sentimientos y apelaciones. El presente trabajo busca demostrar este planteamiento mediante el análisis semiótico del noticiario 24 horas Central de TVN, utilizando para ello el paradigma de Charles Morris.

  6. Descriptive aspects of space on Guimarães Rosa's “A hora e vez de Augusto Matraga”: an initiation on journey

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    João Gomes da Silva Neto

    2013-12-01

    Full Text Available This paper focuses on some textual and discursive aspects of the Guimarães Rosa´s story “A hora e vez de Augusto Matraga”, concerning to description sequences and its role in the configuration of the fictional space. We discuss a narrative matrix whose spatial and temporal structures reveal a trajectory towards the human being redemption – a kind of initiation journey, marked by the mystic of an ascetic life. The analyses also points to the recurrent themes of violence and religiousness that support the narrative tension, straightly related to the protagonist conflicts. Violence and religiousness express the initiation journey paradoxes. Our methodology adopts theoretical contributions of the Pragmatic Linguistics and the Textual Analysis of the Discourses.

  7. Insuficiencia venosa crónica en trabajadores sin factores de riesgo que permanecen horas prolongadas en bipedestación

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    Paula Astudillo

    Full Text Available La insuficiencia venosa crónica (IVC es una patología prevalente en la sociedad actual. Los problemas derivados de ella, son una causa importante de gasto económico y absentismo laboral. Las condiciones laborales actuales, como jornadas de larga duración, con largas horas en bipedestación, inadecuada carga de pesos y malas condiciones de humedad y temperatura, contribuyen al desarrollo de esta patología. En este trabajo se ha realizado una revisión sistemática de la bibliografía existente en relación a la insuficiencia venosa crónica y el tiempo en bipedestación de las jornadas laborales. Para determinar el nivel de evidencia de los estudios evaluados, se han seguido los criterios del Scottish Intercollegiate Guidelines Network (SIGN. En particular, se ha concluido que existe una asociación significativamente positiva entre el tiempo prolongado en bipedestación y el riesgo de padecer insuficiencia venosa crónica. Sin embargo, la literatura actual no permite establecer un umbral que determine el número de horas considerado como bipedestación prolongada. Para poder valorar si la insuficiencia venosa crónica debería considerarse una enfermedad profesional, es necesario diseñar y llevar a cabo nuevos estudios de investigación en esta dirección. Estos estudios son necesarios para poder establecer evidencias de cara a concienciar a la sociedad y generar campañas de prevención y promoción de la salud que disminuyan los costes económicos y mejoren la calidad de vida de la población.

  8. Adaptação de instrumento para dimensionar horas diárias de assistência de enfermagem residencial Adaptacion de instrumento para medir horas diarias de atención de enfermería domiciliaria Adaptation of an instrument for the measurement of daily hours for nursing care at patient's home

    Directory of Open Access Journals (Sweden)

    Luiza Watanabe Dal Ben

    2004-03-01

    Full Text Available O Therapeutic Intervention Scoring System Intermediate: TISS-Intermediário foi traduzido para a língua portuguesa e adaptado para estabelecer horas diárias de assistência domiciliar. O processo de modificação do instrumento, desenvolvido através da Técnica Delphi, teve como participantes 16 enfermeiros, que atuam em empresas de assistência domiciliar e determinam horas diárias de assistência de enfermagem para pacientes na residência, após a hospitalização. Ao término do estudo obteve-se um instrumento com 104 itens, para ser no futuro validado clinicamente. Tal instrumento ajudará enfermeiros a estender cuidados de enfermagem a pacientes em casa, após a alta hospitalar, especialmente na tomada de decisões relativas à avaliação dos pacientes.El Therapeutic Intervention Scoring System Intermediate: TISS-Intermedio, fue traducido para el idioma portugués y adaptado para establecer las horas diarias de asistencia en el domicilio. Dieciséis enfermeros participaron del proceso de modificación del instrumento desarrollado a través de la Técnica Delphi. Esos enfermeros actúan en empresas de atención a domicilio y determinan las horas diarias de atención de enfermería a los pacientes en su domicilio después del alta. Al término del estudio se obtuvo un instrumento con 104 items para ser validado clínicamente.Tal instrumento ayudará a los enfermeros a extender sus cuidados de enfermería a pacientes que se encuentran en casa, después del alta hospitalario, especialmente en la toma de decisiones relacionadas con la evaluación de los pacientes.The Therapeutic Intervention Scoring System Intermediate: TISS-Intermediate, was translated into Portuguese and adapted to establish the number of hours daily of home care. The adaptation process of the instrument, developed with the Delphi Technique, used 16 nurses, who work in home care service providers and helped in calculating the number of nursing care hours for patients at

  9. A abreviação do jejum pré-operatório para duas horas com carboidratos aumenta o risco anestésico? ¿La Reducción del ayuno preoperatorio en dos horas con carbohidratos aumenta el riesgo anestésico? Does abbreviation of preoperative fasting to two hours with carbohydrates increase the anesthetic risk?

    Directory of Open Access Journals (Sweden)

    Kátia Gomes Bezerra de Oliveira

    2009-10-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O objetivo do presente estudo foi avaliar o surgimento de possíveis complicações anestésicas relacionadas à abreviação do jejum pré-operatório para duas horas com uma solução contendo dextrinomaltose a 12,5% dentro do projeto ACERTO (Aceleração da Recuperação Total Pós-operatória. MÉTODO: Foram avaliados prospectivamente todos os pacientes submetidos a diversas operações sobre o trato digestivo e parede abdominal dentro de um novo protocolo de condutas perioperatórias estabelecidas pelo projeto ACERTO entre agosto de 2005 e dezembro de 2007. Todos receberam o suplemento nutricional (dextrinomaltose a 12,5% por via oral seis e duas horas antes do procedimento cirúrgico. A coleta de dados foi prospectiva sem o conhecimento dos profissionais do serviço. Observou-se o tempo de jejum pré-operatório e as complicações anestésicas relacionadas ao curto tempo de jejum (broncoaspiração. RESULTADOS: Foram avaliados 375 pacientes, sendo 174 homens (46,4% e 201 mulheres (53,6% entre 18 e 90 anos de idade O tempo médio de jejum pré-operatório foi de quatro horas variando de duas a 20 horas. Não houve nenhum caso de broncoaspiração durante os procedimentos. O tempo de jejum foi maior (p JUSTIFICATIVA Y OBJETIVOS: El objetivo del presente estudio, fue evaluar el surgimiento de posibles complicaciones anestésicas relacionadas con la reducción del ayuno preoperatorio en dos horas con una solución que contiene dextrinomaltosa a 12,5% dentro del proyecto ACERTO (Aceleración de la Recuperación Total Postoperatoria. MÉTODO: Se evaluaron de forma prospectiva, todos los pacientes sometidos a diversas operaciones sobre el tracto digestivo y la pared abdominal, dentro de un nuevo protocolo de conductas perioperatorias establecidas por el proyecto ACERTO, entre agosto de 2005 y diciembre de 2007. Todos recibieron el suplemento nutricional (dextrinomaltosa a 12,5% por vía oral seis y dos horas antes del

  10. Cuadros en movimiento: la pintura en el cine: Relaciones intermediales en La hora de los valientes [Mercero 1998] y Te doy mis ojos [Bollaín 2003

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    Esther Gimeno Ugalde

    2011-12-01

    Full Text Available The objective of this article is to study the relationship between cinema and painting from an intermedial perspective by analysing two Spanish films: La hora de los valientes (Antonio Mercero 1998 and Te doy mis ojos (Icíar Bollaín 2003. We intend to compare how the respective directors use painting to construct and enrich the cinematographic story and to analyse what narrative and artistic role the paintings play in the filmic text. The study of the two films will serve to illustrate our initial hypothesis, that painting is used not only for artistic and narrative purposes, but also to make the spectator a witness of a twofold drama: the individual and the collective. The exchange of looks which permeates the diegesis places painting to the forefront, whilst determining the interpretation of the filmic textBasándonos en un enfoque teórico intermedial, el presente artículo tiene como objeto estudiar las relaciones entre cine y pintura a partir de dos películas españolas: La hora de los valientes [Antonio Mercero 1998] y Te doy mis ojos [Icíar Bollaín 2003]. Nos proponemos cotejar cómo los respectivos directores introducen la pintura para construir y enriquecer el relato cinematográfico y analizar qué función narrativa y estética cumplen los cuadros en el texto fílmico. El estudio de ambos filmes nos servirá para demostrar nuestra hipótesis inicial: la pintura se emplea no solo con fines estéticos y narrativos, sino también para convertir al espectador en testigo de un doble drama, el individual y el colectivo. El juego de miradas que atraviesa la diégesis sitúa a la pintura en un primer plano, a la vez que determina la lectura del texto fílmico

  11. AVALIAÇÃO DO SUCO RUMINAL DE BOVINOS “A FRESCO” E APÓS 12 HORAS DE CONSERVAÇÃO

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    Patrícia Lorena Guimarães

    2006-10-01

    Full Text Available Avaliaram-se no presente estudo os parâmetros físicos (cor, odor, consistência e tempo de sedimentação e flotação, químicos (pH, e tempo de redução do azul de metileno e biológicos (avaliação dos protozoários in vitro, contagem de infusórios e percentagem de protozoários viáveis do suco ruminal de 50 fêmeas bovinas adultas clinicamente saudáveis, imediatamente após a colheita e ao final de 12 horas de armazenamento em garrafas térmicas comuns. Utilizaram-se animais em lactação, da raça Girolando, e alimentados a pasto de Brachiaria decumbens. As análises foram realizadas em uma amostra individual de, aproximadamente, 400 ml de suco ruminal, colhida com sonda oroesofágica do tipo Schambye e Sorensen. Os resultados foram avaliados por meio de estatística descritiva e teste “t” de student para amostras pareadas (P<0,05. Os aspectos físicos, a avaliação in vitro dos infusórios e o número de protozoários por mililitro encontravam-se dentro dos padrões de normalidade na primeira avaliação, porém, após 12 horas de conservação, foram observadas alterações sugestivas de modificações na microbiota do suco ruminal. Constataram-se, após conservação, reduções estatísticas significativas em relação ao pH, percentual de protozoários viáveis e aumento no tempo de redução do azul de metileno (PRAM. Conclui-se que a garrafa térmica comum pode ser usada como opção na conservação de suco ruminal de bovinos em situações de clínica de campo, porém a análise no momento da colheita apresenta resultados mais fidedignos. PALAVRAS-CHAVE: Bovinos, fluido ruminal, métodos de conservação, pH, protozoários.

  12. Esofagomanometria e phmetria de 24 horas para avaliar a fundoplicatura de lind laparoscópica na doença do refluxo gastroesofágico

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    Pablo Roberto Miguel

    Full Text Available As técnicas laparoscópicas e toracoscópicas proporcionaram uma nova dimensão para a correção dos distúrbios funcionais do esôfago. O sucesso terapêutico, entretanto, depende da confirmação da doença esofágica como causa dos sintomas, da compreensão da causa básica da disfunção e da identificação do paciente cirúrgico. O presente trabalho é um estudo retrospectivo em pacientes operados pela técnica de Lind para doença do refluxo gastroesofágico (DRGE. Tem por objetivo estabelecer o valor do uso sistemático da esofagomanometria e da pHmetria de 24 horas na seleção de pacientes e na avaliação funcional pré e pós-operatória. Quarenta e um pacientes (68,3% tinham hipotonia do esfíncter inferior do esôfago. A pressão foi em média de 9,2 mmHg no pré-operatório e de 15,2mmHg no pós-operatório, com um aumento de 6,0 mmHg. Este aumento foi de 8,8mmHg nos hipotônicos e 4,3 mmHg nos normotônicos. Houve algum grau de hipomotilidade do corpo do esôfago em 14 pacientes (23,3%, sendo que, deste grupo, quatro (28,5% obtiveram melhora pós-operatória. Refluxo ácido patológico foi constatado em 51 casos (85,0% pela pHmetria. A média do score de DeMeester pré-operatório foi de 31,4, baixando depois para 3,2. A esofagomanometria e a pHmetria de 24 horas são métodos eficazes em revelar o nível de modificação funcional estabelecido pela cirurgia anti-refluxo e ajudam objetivamente na seleção.

  13. Efeitos agudos do exercício físico prolongado: avaliação após ultramaratona de 24 horas

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    Daniela Guinther Passaglia

    2013-01-01

    Full Text Available FUNDAMENTO: As consequências e os riscos do exercício físico contínuo por períodos prolongados não estão esclarecidos. OBJETIVO: Avaliar os efeitos do exercício prolongado em participantes de uma ultramaratona de 24 horas. MÉTODOS: Vinte corredores foram selecionados para avaliação, um dia antes e imediatamente após a prova em que os corredores devem percorrer a maior distância em 24 horas. Foram obtidos dados clínicos, laboratoriais e ecocardiográficos. RESULTADOS: A distância média percorrida foi de 140,3 ± 18,7 km. Os corredores apresentaram redução do peso corpóreo (p < 0,001 e da pressão arterial sistólica (p < 0,001 e diastólica (p = 0,004. As alterações hematológicas foram compatíveis com o estresse fisiológico. A concentração plasmática de creatinofosfoquinase (CPK aumentou significativamente (163,4 ± 56,8 versus 2978,4 ± 1921,9 U/L; p < 0,001 e esteve inversamente correlacionada com a distância percorrida: os que correram maiores distâncias apresentaram níveis mais baixos de CPK (Pearson r = 0,69; p = 0,02. Após a corrida, dois corredores apresentaram discreta elevação de troponina T. Em um deles, houve queda concomitante na fração de ejeção (coronariopatia foi excluída subsequentemente. O ecocardiograma na avaliação basal mostrou hipertrofia de ventrículo esquerdo em um e aumento do volume atrial esquerdo em cinco corredores. Após a prova, houve redução na relação E/A (p < 0,01. CONCLUSÃO: O exercício físico prolongado está associado a alterações cardiovasculares e metabólicas. As alterações cardiológicas encontradas sugerem que o fenômeno de fadiga cardíaca pode ocorrer nessa modalidade de corrida. O efeito a longo prazo dessas alterações, com a manutenção da prática desse tipo de atividade, ainda é desconhecido.

  14. Correlación entre algunos parámetros climáticos y la hora del día en Heredia, Costa Rica.

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    Jaime Wright

    2016-03-01

    Full Text Available Se midieron las radiaciones solar global, infrarroja y ultravioleta, la presión atmosférica, la temperatura del aire, la humedad relativa y la velocidad del viento en Heredia, Costa Rica (latitud 10° 02’ N, longitud 84° 09’ W, altitud 1050 m durante el período de enero 1996 a diciembre 1997, y se correlacionaron con el tiempo local. Este trabajo contribuirá al desarrollo de un modelo para derivar parámetros climáticos a partir de la hora del día. Correlaciones entre parámetros climáticos y el mes del año han sido desarrolladas en investigaciones anteriores. Análisis de regresión entre valores horarios medios mensuales de los parámetros climáticos y el tiempo local mostraron una relación cúbica como mejor método de ajuste. Las observaciones experimentales presentadas en este estudio son consistentes con los esperados procesos físicos conocidos.

  15. Energy expenditure after 2- to 3-hour elective surgical operations Gasto energético após 2 ou 3 horas de cirurgia eletiva

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    Andrea Ferreira Schuwartz Tannus

    2001-04-01

    Full Text Available Energy expenditure was measured by indirect calorimetry in 17 adult patients (8 women and 9 men before surgery, 4 hours immediately after surgery , and 24 hours late after surgery in patients undergoing elective surgery of small-to-medium scope. MATERIAL AND METHODS: The total duration of surgery ranged from 2 to 3 hours. Repeated measures were performed on the same patient, so that each patient was considered to be his/her own control. All patients received a 5% dextrose solution (2000 mL/day throughout the postoperative period. RESULTS: Men showed a reduction in CO2 production during the immediately after surgery period (257±42 mL/min compared to before surgery (306±48 mL/min and late after surgery (301±45 mL/min; this reduction was not observed in women. Energy expenditure was also lower in men during immediately after surgery (6.6 kJ/min. None of the other measurements, including substrate oxidation, showed significant differences. CONCLUSION: Therefore, elective surgery itself cannot be considered an important trauma that would result in increased energy expenditure. According to this study, it is not necessary to prescribe an energy supply exceeding basal expenditure during the immediate after-surgery period. The present results suggest that the energy supply prescribed during the postoperative period after elective surgery of small-to-medium scope should not exceed 5-7 kJ/min, so the patient does not receive a carbohydrate overload from energy supplementation.A resposta metabólica ao trauma cirúrgico ocorre imediatamente após a cirurgia e recomenda-se que a oferta calórica, nesta situação, seja igual ao metabolismo basal acrescido de 20-30%, considerado fator de injúria. No entanto, níveis elevados de glicemia e aumento na produção de CO2 são freqüentemente observados nestas ocasiões . OBJETIVO: O principal objetivo do presente estudo foi medir o gasto energético basal, o gasto energético imediatamente e 24 horas ap

  16. Ensaio clinico com Teclozan: 500mg no tratamento da colite amebiana não disentérica. (Resultados com esquema terapêutico de 24 horas

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    Donald Huggins

    1978-12-01

    Full Text Available O Autor relata sua experiência com novo esquema terapêutico com Teclozan - dose total de 1.500mg empregada em 24 horas, em 40 pacientes portadores de colite amebiana não disentérica na Disciplina de Doenças Infecciosas e Parasitárias da Universidade Federal de Pernambuco. Após um controle de cura realizado no 4º, 8º, 12º e 20º dias após o tratamento, obteve eficácia em 75% dos enfermos (30 casos e excelente tolerância.The author report his experience with Teclozine in the treatment on 40 patients suffering chronic intestinal amebiasis, employing a new therapeutical schedule - 1,500 mg as the total dose, within the period of 24 hours. After a follow-up on the 4th, 8th, 12th, and 20th days of treatment, the parasitological cure rate obtained was 75% (30 cases, and the drug was very well tolerated by all the patients.

  17. Cambios en la medida de las horas de insolación: Análisis de su impacto en dos observatorios de las Islas Baleares (España

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    José A. Guijarro

    2007-12-01

    Full Text Available Se han comparado las medidas de horas de sol realizadas en paralelo con el heliógrafo Campbell-Stokes, utilizado tradicionalmente en los observatorios españoles, con las medidas de los nuevos instrumentos de Kipp&Zonen, basados en el umbral de irradiación directa de 120 Wm-2. La comparación se ha realizado con los datos de dos observatorios de Baleares, ubicados en los aeropuertos de Menorca e Ibiza, en los que las nuevas medidas son generalmente inferiores a las antiguas, con diferencias medias diarias de -0,97 y -0,58 horas respectivamente. En términos relativos, la disminución respecto al promedio anual del periodo 1971-2000 es de un 13,2% en Menorca y un 7,8% en Ibiza. Se han realizado ajustes por regresión lineal simple y múltiple que explican un 94% de la varianza de la insolación diaria. Las ecuaciones obtenidas pueden servir para homogeneizar las series de datos diarios de horas de sol, con errores típicos de 0,98 horas en el aeropuerto de Menorca y 0,86 en el de Ibiza, pero no son aplicables a otros observatorios.

  18. Perfil das mães de neonatos com controle glicêmico nas primeiras horas de vida Perfil de las madres de neonatos con control glucémico en las primeras horas de vida Profile of mothers of newborns with blood glucose control in the first hours of life

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    Patrícia de Freitas

    2010-09-01

    Full Text Available Alguns fatores maternos associados ao quadro de hipoglicemia neonatal indicam a monitoração dos níveis glicêmicos nas primeiras 24 horas de vida. O estudo objetivou descrever as características sócio-demográficas e obstétricas de mães de neonatos com controle de glicemia capilar nas primeiras 24 horas de vida, internadas em Alojamento Conjunto de um Hospital Amigo da Criança. Estudo descritivo-exploratório que analisou dados de 380 prontuários médicos de mães internadas entre julho e dezembro de 2006, na unidade de Alojamento Conjunto do Hospital Universitário da Universidade de São Paulo. Diabetes gestacional foi verificado em 18 (5,6% mães; nenhuma tratou com hipoglicemiante oral; 53 (16,2% tiveram hipertensão arterial na gestação, e 17 (32,1% fizeram uso de anti-hipertensivo; 215 (56,6% receberam soro glicosado, 5% no trabalho de parto e parto. Estudos correlacionais analisando variáveis maternas e ocorrência de hipoglicemia neonatal devem ser realizados, objetivando identificar os fatores preditores desta morbidade neonatal.Algunos factores maternos asociados al cuadro de hipoglucemia neonatal indican la monitorización de los niveles de glucemia en las primeras 24 horas de vida. El estudio tuvo como objetivo describir las características sociodemográficas y obstétricas de madres de neonatos con control de glucemia capilar en las primeras 24 horas de vida, internadas en Alojamiento Conjunto de un Hospital Amigo de la Niñez. Estudio de tipo descriptivo exploratorio que analizó datos de 380 historias clínicas de madres internadas entre julio y diciembre de 2006 en la Unidad de Alojamiento Conjunto del Hospital Universitario de la Universidad de San Pablo. Se verificó diabetes gestacional en 18 madres (5,6%, ninguna recibió tratamiento con hipoglucemiantes orales, 53 de ellas (16,2% tuvieron hipertensión arterial durante la gestación y 17 (32,1% hicieron uso de antihipertensivos; 215 (56,6% recibieron suero

  19. Restructuring the Nursing Staff and its Influence on Care Hours Reestructuración del cuadro de personal de enfermería y su impacto sobre las horas de asistencia Reestruturação do quadro de pessoal de enfermagem e seu impacto sobre as horas de assistência

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    Danielle Fabiana Cucolo

    2010-04-01

    Full Text Available This descriptive study aimed to calculate and compare the nursing staff at the medical-surgical clinical units of a philanthropic hospital in current and projected situations, and to investigate how much time the nursing team delivers patient care in the current and projected situations. Gaidzinski's method was used to calculate the nursing staff, and the equation proposed by the Hospital Quality Commitment (HQC to estimate care hours. The findings showed an increase of 33% in the staff, with a 68.4% increase in the number of nurses and 15.6% in the number of technicians / nursing auxiliaries. According to the projected situation, the care hours varied from 5.7 to 7.2. The number of nursing and the mean care time provided to the patients were inadequate according to the clientele's care needs. This could impair the quality of care.Este estudio descriptivo tuvo por objetivo dimensionar y comparar el cuadro de personal de enfermería de las unidades de clínica médico-quirúrgica de un hospital filantrópico, en las situaciones actuales y proyectadas, e investigar el tiempo de asistencia utilizado en los pacientes por el equipo de enfermería en las dos situaciones. Para dimensionar se utilizó el método propuesto por Gaidzinski, y, para el cálculo de las horas de asistencia, la ecuación propuesta por el Compromiso con la Calidad Hospitalaria (CCH. Lo encontrado colocó en evidencia la necesidad de aumentar en 33% el cuadro de personal, con aumento de 68,4% de enfermeros y de 15,6% en el número de técnicos/auxiliares de enfermería. En la situación proyectada, las horas de asistencia variaron de 5,7 a 7,2. El cuantitativo de enfermería y el tiempo promedio utilizado con los pacientes se revelaron inadecuados para atender las necesidades de la clientela, lo que puede comprometer la calidad de la asistencia.Este estudo descritivo objetivou dimensionar e comparar o quadro de pessoal de enfermagem das unidades de clínica médico-cirúrgica de

  20. Participação nos lucros ou resultados e banco de horas: intensidade do trabalho e desgaste operário

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    José Augusto Pina

    Full Text Available INTRODUÇÃO: As transformações operadas no processo de trabalho na indústria automobilística no Brasil desde os anos 1990 apontam para o fortalecimento da gestão da força de trabalho como um dos determinantes do processo saúde-doença dos trabalhadores. OBJETIVOS: Discutem-se dois elementos da gestão: a participação nos lucros ou resultados (PLR e o banco de horas (BH e assinala-se a relação de ambos com a intensidade do trabalho e o desgaste operário. Métodos: Apóia-se em revisão bibliográfica e em análise dos acordos coletivos dos metalúrgicos do ABC-SP, entre 2001 e 2008. RESULTADOS: A análise realizada mostrou que a reorganização do tempo de trabalho, o prolongamento da jornada e a manutenção do elevado grau de intensidade do trabalho ocasionados pelo BH e as metas vinculadas à PLR exercem pressão sobre o trabalhador para o aumento quantitativo e qualitativo do trabalho, evidenciando que esses instrumentos gerenciais propiciam a intensificação do trabalho e o desgaste operário. Também afetam drasticamente o tempo de não trabalho fora da jornada, inclusive prejudicando a reposição e o desenvolvimento da capacidade biopsíquica do trabalhador. CONCLUSÃO: A PLR e o BH podem ser caracterizados como uma forma de administração por estresse que eleva e potencializa as cargas de trabalho e o desgaste operário.

  1. Pressão arterial de 24 horas em mulheres idosas normotensas e com hipertensão do avental branco Presión arterial de 24 horas en mujeres mayores normotensas y con hipertensión de la bata blanca 24-hour blood pressure in normotensive elderly women and elderly women with white-coat hypertension

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    Paulo Rogério W. Hekman

    2010-04-01

    Full Text Available FUNDAMENTO: Mudanças no comportamento do ritmo circadiano podem ser deletérias, levando à lesão de órgãos-alvo, o que sugere ser de importante significado prognóstico e, eventualmente, podem também demandar intervenção terapêutica. OBJETIVO: Descrever e comparar os ritmos circadianos de pressão arterial (PA entre mulheres idosas normotensas e portadoras de hipertensão do avental branco (HAB. MÉTODOS: Estudo transversal em uma amostra de 36 pacientes, com idades entre 60-83 anos, submetidas à monitorização ambulatorial de pressão arterial (MAPA durante 24 horas. Dezenove idosas normotensas e 17 com HAB foram comparadas quanto à queda noturna e variabilidade de PA, ascensão matinal da PAS, pressão de pulso, hipotensão pós-prandial e correlação de médias de PA de 24 horas. Na análise estatística, utilizou-se o teste t de Student, teste do qui-quadrado, teste exato de Fisher e teste de correlação linear de Pearson. RESULTADOS: As idosas com HAB apresentaram níveis mais elevados de PAS do que as normotensas, entre 8-12 horas (133 ± 8,0 mmHg vs 123 ± 9,0 mmHg, respectivamente, p FUNDAMENTO: Cambios en el comportamiento del ritmo circadiano pueden ser perjudiciales, conduciendo a la lesión de órganos blanco, lo que sugiere ser de importante significado pronóstico y, eventualmente, pueden también demandar intervención terapéutica. OBJETIVO: Describir y comparar los ritmos circadianos de presión arterial (PA entre mujeres mayores normotensas y portadoras de hipertensión de la bata blanca (HABB. MÉTODOS: Estudio transversal en una muestra de 36 pacientes, con edades entre 60-83 años, sometidas a monitoreo ambulatorio de presión arterial (MAPA durante 24 horas. 19 mujeres mayores normotensas y 17 con HABB fueron comparadas con relación a la caída nocturna y variabilidad de la PA, ascenso matinal de la PAS, presión de pulso, hipotensión postprandial y correlación de promedios de PA de 24 horas. En el an

  2. Avaliação da função renal do idoso em duas horas Evaluación de la función renal de ancianos en dos horas Two-hour evaluation of renal function in the elderly

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    Maria do Carmo B. Sammartino Benarab

    2005-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Os idosos têm diminuição progressiva da função renal e os hipertensos, maior risco de lesão renal adicional no intra-operatório. Avalia-se a função renal pela depuração da creatinina, com débito urinário de 24 horas, para diluir o erro de possível volume vesical residual (VVR. O objetivo deste trabalho foi avaliar a função renal pré-operatória de idosos hipertensos e não-hipertensos, com débito urinário de duas horas, utilizando aparelho de ultra-som portátil para determinação do volume vesical residual. MÉTODO: Foram analisados 30 pacientes, distribuídos em dois grupos, Gn (15, idosos não-hipertensos, e Gh (15, idosos hipertensos, coletando-se urina durante 2 horas. Mediu-se o VVR com aparelho de ultra-som portátil. Analisaram-se os seguintes parâmetros: idade, sexo, estado físico, altura, peso, índice de massa corpórea, creatinina plasmática e urinária, sódio e potássio plasmáticos e urinários, osmolalidade plasmática e urinária, débito urinário, depuração da creatinina, osmolar e de água livre, excreção urinária e fracionária de sódio e potássio. Comparou-se a depuração estimada de creatinina com a depuração da creatinina. RESULTADOS: Os pacientes de Gn e Gh não apresentaram diferenças significativas quanto à maioria dos parâmetros estudados. Os idosos hipertensos apresentaram tendência a maior excreção fracionária de sódio e o potássio plasmático mostrou-se mais baixo nos hipertensos, porém com valores normais. A depuração estimada de creatinina correlacionou-se positivamente com a de creatinina apenas em Gn. CONCLUSÕES: Os pacientes hipertensos apresentaram potássio plasmático mais baixo e excretaram mais sódio, tendo ocorrido correspondência entre a depuração estimada de creatinina e a depuração da creatinina apenas para os pacientes do grupo dos não-hipertensos.JUSTIFICATIVA Y OBJETIVOS: Los ancianos tienen disminución progresiva de

  3. Two ways of constructing the reader`s subject position: a discursive analysis of the newspaper language of the newspapers Diário Catarinense and Hora de Santa Catarina

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    Sandro Braga

    2012-12-01

    Full Text Available We analyze, based on French Discourse Analysis, how the newspapers Diário Catarinense and Hora de Santa Catarina produce different reader`s subject positions. This research is justified by the fact that both newspapers are products of the same media company. The starting point was the hypothesis that there would be in the market two types of readers, thus the two products do not compete with each other, but they would complement each other in the coverage of a reading area. Reading here is treated as a process of production of sense effects. The work is based on Orlandi`s thinking about the conception of reading, as well as in the distinction between real and virtual reader. We do also present the clues included in the statements which inferences are essential to apprehend the said and the unsaid which, by means of a comparative analysis, was used to understand the production of different reader’s subject position. The analysis points out that the newspapers DC and Hora present similar characteristics in regard to the process of transmitting information, howevereach newspaper interrelates with its target public in a different way through the use of language and in the manner of production of news. It leads to the construction of different positions of these readers in relation to the information which is transmitted, because, making use of uttering strategies, these newspapers ideologically mark the readers of DC as being more lettered than the ones of Hora.

  4. Estimativa do total de horas abaixo de determinada temperatura-base através das medidas diárias da temperatura do ar Number of hours below any base temperature estimated by daily measurements of air temperature

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    Luiz B. Angelocci

    1979-01-01

    Full Text Available São propostas equações matemáticas para estimar o total diário de horas abaixo de determinada temperatura-base, em certo período, utilizando-se somente dos valores diários das temperaturas máxima, mínima e das 21 horas (hora local. A comparação entre os totais diários e mensais de "horas de frio" estimados pelas equações propostas e os observados através de termogramas, para várias localidades do Estado de São Paulo, mostrou boa concordância entre os métodos de cálculo. O modelo proposto dispensa o uso de registros contínuos de temperatura. As vantagens de tal estimativa residem na maior disponibilidade de registros de temperaturas máximas, mínimas e das 21 horas, permitindo maior densidade de pontos em trabalhos de zoneamento agroclimático e de cartografia, além da eliminação do processo de cotação de termogramas.Mathematical equations are proposed to estimate the daily number of hours in which the air temperature remains below a determined treshold value. The equations require only daily values of maximum, minimum and 9 p.m. local time temperature, measured inside the meteorological shelter. This technique is suitable for machine computation thus avoiding the tremendous task of quantifying a large number of thermograms. This fact permits the utilization of a greater number of stations in studies of crop zonation and cartography. Good correlations were obtained between estimated and observed data of the daily and monthly total number of hours below 7°C, 13°C and 17°C, for five stations in the State of São Paulo, Brazil, showing relative accuracy of the proposed equations.

  5. La lectura por placer: su incidencia en el rendimiento académico, las horas de televisión y las horas de videojuegos. The pleasure of reading: its impact on academic achievement, on TV-watching hours and video games-playing hours

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    Teresa Dezcallar

    2014-11-01

    Full Text Available En el presente trabajo se ha relacionado el gusto y la afición por la lectura y el tiempo que pasan los alumnos viendo la televisión o jugando a videojuegos en los ratos de ocio, y cómo estas variables correlacionan con el rendimiento académico, medido a través de las notas escolares. La muestra ha sido compuesta por un total de 510 alumnos de los tres ciclos de educación primaria de escuelas públicas y privadas españolas. Los datos se obtuvieron mediante cuestionarios dirigidos a los padres. Los resultados han revelado que la lectura por placer correlaciona de forma positiva con las notas académicas y de forma negativa con las horas de visionado de televisión. This paper relates the pleasure and the fondness for reading to the time students spend watching TV or playing video games in their leisure time, and how these correlate with academic performance, measured by school marks. The sample comprised a total of 510 Spanish Primary School students from public and private schools. Data were obtained through questionnaires administered to parents. The results showed that the pleasure of reading mantained significant and positive relationships with academic marks and correlate negatively with television watching hours.

  6. Horas de sono e índice de massa corporal em pré-escolares do sul do Brasil Sleep duration and body mass index among southern Brazilian preschoolers

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    Maria Laura da Costa Louzada

    2012-12-01

    Full Text Available A prevenção e o tratamento do excesso de peso são particularmente complexos, reforçando a importância de estudos que visem esclarecer sua rede de causas e efeitos. Assim, o objetivo desse estudo foi avaliar a relação entre horas de sono noturnas e medidas antropométricas. Realizou-se uma análise transversal realizada a partir de dados de 348 crianças de 3 e 4 anos da cidade de São Leopoldo/ RS. As horas de sono noturnas foram relatadas pelas mães e as medidas de índice de massa corporal, circunferência da cintura e dobras cutâneas foram medidas de acordo com protocolo padrão. As análises foram ajustadas para consumo energético e horas de televisão assistidas. As crianças com excesso de peso apresentaram, em média, 0,39 horas a menos de sono em relação àquelas com peso adequado (9,77 ± 1,44 versus 10,17 ± 1,34; IC95% 0,03-0,76. Observou-se associação inversa entre horas de sono noturnas e valores de escore z de índice de massa corporal para idade (B = -0,12 IC95% -0,22--0,02. A circunferência da cintura e as dobras cutâneas apresentaram relação inversa com as horas de sono, porém sem diferença estatística. Em pré-escolares do sul do Brasil, menos horas de sono noturnas foram associadas com maiores valores de índice de massa corporal.Prevention and treatment of overweight are particularly complex, reinforcing the importance of studies aimed at clarifying their range of causes and effects. Thus, the objective of this study was to evaluate the relationship between night sleep duration and anthropometric measurements. A cross-sectional analysis was performed from data from 348 children aged 3 and 4 years in São Leopoldo/RS. Night sleep duration was reported by their mothers and body mass index, waist circumference and skinfold thickness were measured according to standard protocol. The analyses were adjusted for energy intake and hours of television watching. Overweight children had, on average, 0.39 hours less

  7. Generación de electricidad en horas de punta a partir de la digestión anaeróbica de camalote

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    A. Maioli

    2011-06-01

    Full Text Available El presente trabajo tiene como objeto de presentar una propuesta novedosa y sustentable para la generación de energía eléctrica en el área metropolitana de Asunción basada en una fuente renovable de energía. Dicha generación se realizaría principalmente en horas de punta con el fin de reducir la potencia contratada por la ANDE en las usinas existentes y de esta forma disminuir costos y al mismo tiempo estabilizar las redes de transmisión y de distribución en la zona de Asunción. La electricidad se generaría en una planta térmica de ciclo combinado de 130 MW de potencia instalada utilizando como combustible biogás obtenido por medio de la digestión anaeróbica en biodigestores de plantas de camalote cultivadas en piletas a ser construidas en la orilla del río Paraguay frente al Jardín Botánico de Asunción. La principal ventaja para el aprovechamiento del camalote es su elevado índice de crecimiento, que es entre 100 y 500 g por día y por m2 según las condiciones ambientales, lo que permite que se duplique su masa vegetal cada 6 a 15 días. La relación entre carbono y nitrógeno, que se encuentra en su masa vegetal es óptima para la generación de biogás, cuyo poder calorífico de unos 6,4 kWh/m3 es suficientemente elevado para utilizarlo para la generación de calor y por ende también de electricidad en una planta térmica. Esa usina podría conectarse directamente al SIN a través de la Estación de Puerto Botánico mediante una línea de transmisión en 220 kV de 2 km cruzando el río Paraguay. Mediante este proyecto la ANDE podría ahorrar por año hasta US$ 25,000,000 en concepto de la contratación de potencia en la represa de Itaipú. Aunque dicho ahorro se reduciría cada año de 3% por el incremento de la demanda, la inversión de unos US$ 98,000,000 podría ser amortizada en un plazo de 15 años y tendrá un TIR del 5% y un VAN de US$ 40,548,000

  8. Efecto de la implantación de turnos de enfermería «a demanda» sobre las horas de absentismo Effect of the introduction of "on demand" nursing shifts on hours of absenteeism

    Directory of Open Access Journals (Sweden)

    Joaquín Jesús Blanca Gutiérrez

    2012-10-01

    Full Text Available El objetivo de esta experiencia es estudiar la influencia en el absentismo del personal de enfermería de un nuevo sistema de turnos rotatorios, con la novedad de que tanto la distribución horaria como la planificación y la adjudicación de los turnos se ha hecho según las demandas del propio personal. El lugar de realización ha sido el Hospital Infanta Margarita, de Cabra (Córdoba, España, y la implementación de los nuevos turnos fue durante el primer trimestre de 2011. De un total de 5551 horas absolutas de ausencia por semestre, se ha pasado a 3289 horas. La implantación de este nuevo sistema de turnos «a demanda» parece haber conseguido una reducción notable en el número de horas de ausencia del trabajo. Se trata de una estrategia para tratar de conciliar al máximo la jornada laboral con la vida personal y familiar.The objective of this study was to analyze the effect of the introduction of a new system of rotating shifts on nursing absenteeism. The novelty of this system is that both the time distribution and the planning and allocation of shifts is carried out according to the wishes of the participating nurses. This study was performed in the Infanta Margarita Hospital (Cordoba, Spain and the new shift system was introduced in the first quarter of 2011. The total number of absolute hours of absence decreased from 5551 to 3289 per semester. The implementation of this new "on demand" shift system seems to have significantly reduced hours of absence. This strategy aims to reconcile nurses´ working hours with their personal and family lives.

  9. Current strategy for leprosy control in Brazil: time to pursue alternative preventive strategies? Estrategia actual para el control de la lepra en Brasil: ¿es hora de investigar otras estrategias de prevención?

    OpenAIRE

    Sérgio S. Cunha; Laura C. Rodrigues; Nádia Cristina Duppre

    2004-01-01

    La estrategia actual para el control de la lepra en Brasil se basa en dos actividades principales: la detección precoz de casos y el tratamiento de casos con farmacoterapia combinada. Además de dichas medidas, se realizan esfuerzos complementarios para identificar los contactos domésticos para el diagnóstico precoz y la vacunación con el bacilo de Calmette-Guérin (BCG). Sin embargo, la eficacia de estas acciones a la hora de reducir la incidencia de la lepra es aún discutible. Esto genera dud...

  10. La tuberculosis de “Doc” Holliday en el cine. La hora de las pistolas/ Hour Of The Gun (1967 y Duelo a muerte en O.K. Corral/ “Doc” (1971

    Directory of Open Access Journals (Sweden)

    José Elías García Sánchez

    2008-10-01

    Full Text Available La hora de las pistolas (1967 de John Sturges comienza en el famoso duelo en el O.K. Corral mientras que Duelo a muerte en O.K. Corral (1971 de Frank Perry, como sus predecesoras Pasión de los fuertes (1946 y Duelo de titanes (1957 termina en él. Ambas películas muestran la tuberculosis pulmonar de “Doc” Holliday. La primera incide especialmente en sus últimos días en el sanatorio antituberculoso de Glenwood Springs y la segunda, en la que es el protagonista, con sus intensos ataques de tos.

  11. Aleitamento materno na primeira hora de vida em um Hospital Amigo da Criança: prevalência, fatores associados e razões para sua não ocorrência

    Directory of Open Access Journals (Sweden)

    Mércia Natália Macêdo Belo

    2014-03-01

    Full Text Available Objetivos: identificar a prevalência do aleitamento materno na primeira hora de vida, os fatores associados e as razões para sua não ocorrência em um Hospital Amigo da Criança. Métodos: estudo transversal com 562 mães e recém-nascidos. Os dados foram obtidos entre outubro a novembro de 2011 mediante formulários de entrevista e consulta a prontuários. Modelo de Poisson foi ajustado para analisar a prevalência do aleitamento materno na primeira hora de vida em função das variáveis de exposição. Resultados: a prevalência do aleitamento materno na primeira hora de vida foi de 31%. Apenas o parto normal permaneceu no modelo final, apresentando razão de prevalência de 27% a mais em relação ao parto cesáreo (p=0,020. As razões para que 388 crianças não tenham sido amamentadas na primeira hora de vida foram classificadas em: problemas de saúde da criança (328, 84,5%, da mãe (241, 62,1% e atraso no resultado do teste rápido anti-HIV (199, 51,2%, 11 (2,8% não apresentaram nenhuma justificativa. Conclusões: os resultados relatados ainda estão bem abaixo das recomendações da Organização Mundial da Saúde (OMS, o que em grande parte pode ser atribuído às condições próprias de um hospital de nível terciário, cuja demanda é constituída predominantemente por casos de pacientes de médio e elevado risco obstétrico.

  12. HIV/AIDS, childhood and governance: sundering the bonds of human society.

    Science.gov (United States)

    Barnett, Tony

    2005-12-01

    There is a disharmonious resonance between the length of HIV infection in the individual human host and the length of a human generation. In brief, an infected person may have children, these may be orphaned and grow up to become infected, and afterwards they themselves may have children, who can be orphaned in turn. Hence, a basic unit of social structure in most human societies, the three-generation bond between grandparents, parents and the current generation - and on into the future - is repeatedly torn apart in the absence of treatment, a vaccine or behaviour change. This situation should be read against the threat of growing viral resistance. Certain implications of these processes for the future are outlined and discussed. The paper notes the uncertain future confronting societies that already have a relatively high number of orphans, and considers some otherwise unexpected possibilities, as well as the dangers of assuming that large-scale orphaning necessarily leads to social unrest and disorder.

  13. Risk management - a case study / Madan Lal Bhasin

    Index Scriptorium Estoniae

    Bhasin, Madan Lal

    2003-01-01

    Autor tutvustab rahvusvahelisel finantsturul toimuvate intressimäära ja valuutakursi kõikumisest tulenevate riskide juhtimise mehhanisme, kasutades intressimäära vahetuslepingut ja fikseeritud kursi lepingut. Tabel

  14. LAL contributions to the 1st EPAC conference

    International Nuclear Information System (INIS)

    Boussoukaya, M.; Dubrovin, A.; Bienvenu, G.; Girault, P.; Bourdon, J.C.

    1988-07-01

    The Linear Accelerator Laboratory contributions to the first European Particle Accelerator Conference, are presented. A new method on the field of high brightness laser driven electron sources, is described. The experimental results, involving high emissivity photocathodes in moderate (30 KV) and high (more than 100 KV) voltage configurations, are given. The simulation code, capable to work on rf devices, is explained; it is able to take advantage of time stepping and to get closer to the real case of the Orsay (France) lasertron. The behaviour of warm accelerating rf structures under high gradient is investigated. The design of the structure, the evaluations of the peak field and the energy gain of a 4 pi/S H-coupled backward TW system, are presented; the device is applied to improve the electron linacs optimixation. The status, the general description, and the main components of the project concerning a 50/80 MeV linac, devoted to an infrared free electron laser, is summarized

  15. Economic capital and risk management / Madan Lal Bhasin

    Index Scriptorium Estoniae

    Bhasin, Madan Lal

    2003-01-01

    Autor käsitleb riskijuhtimist finantsinstitutsioonides, sh. pankades, kasutades majandusliku kapitali süsteeme, mis võimaldavad mõõta ettevõtte riske ja kindlustada võimalike kahjude eest, määratledes vastava vajaliku kapitali määra. Lisa Baseli Komitee ettepanekute kohta. Tabel

  16. The Krásná Hora, Milešov, and Příčovy Sb-Au ore deposits, Bohemian Massif: mineralogy, fluid inclusions, and stable isotope constraints on the deposit formation

    Science.gov (United States)

    Němec, Matěj; Zachariáš, Jiří

    2018-02-01

    The Krásná Hora-Milešov and Příčovy districts (Czech Republic) are the unique examples of Sb-Au subtype orogenic gold deposits in the Bohemian Massif. They are represented by quartz-stibnite veins and massive stibnite lenses grading into low-grade, disseminated ores in altered host rocks. Gold postdates the stibnite and is often replaced by aurostibite. The ore zones are hosted by hydrothermally altered dikes of lamprophyres (Krásná Hora-Milešov) or are associated with local strike-slip faults (Příčovy). Formation of Sb-Au deposits probably occurred shortly after the main gold-bearing event (348-338 Ma; Au-only deposits) in the central part of the Bohemian Massif. Fluid inclusion analyses suggest that stibnite precipitated at 250 to 130 °C and gold at 200 to 130 °C from low-salinity aqueous fluids. The main quartz gangue hosting the ore precipitated from the same type of fluid at about 300 °C. Early quartz-arsenopyrite veins are not associated with the Sb-Au deposition and formed from low-salinity, aqueous-carbonic fluid at higher pressure and temperature ( 250 MPa, 400 °C). The estimated oxygen isotope composition of the ore-bearing fluid (4 ± 1‰ SMOW; based on post-ore calcite) suggests its metamorphic or mixed magmatic-metamorphic origin and excludes the involvement of meteoric water. Rapid cooling of warm hydrothermal fluids reacting with "cold" host rock was probably the most important factor in the formation of both stibnite and gold.

  17. «El mundo desconectado» y «24 horas sin medios»: alfabetización mediática para la conciencia crítica de los jóvenes

    Directory of Open Access Journals (Sweden)

    Susan Moeller

    2012-10-01

    Full Text Available La mayoría de los jóvenes del mundo se conecta habitualmente a los medios de comunicación; sin embargo, en pocas ocasiones reciben formación respecto a los impactos que este consumo mediático tiene en ellos mismos. Este artículo expone la experiencia llevada a cabo en el marco del Currículum UNESCO, denominada «24 horas sin medios». En otoño de 2010, cerca de 1.000 estudiantes de 12 universidades de cuatro continentes participaron en el estudio «El mundo desconectado». Investigadores de la Universidad de Maryland (Estados Unidos recogieron rigurosamente las reflexiones de los alumnos que participaron y las analizaron a través del programa estadístico IBM’s ManyEyes. Los resultados muestran que los jóvenes, a raíz del ejercicio, fueron más conscientes de sus hábitos mediáticos, y muchos de ellos indagaron sobre su propia «adicción» a los medios, mientras que otros no consiguieron siquiera concluir estas 24 horas sin medios. También se pone en evidencia que el acceso cotidiano a la tecnología digital forma parte ya de su identidad juvenil y son básicas para entender su forma de trabajar y sus relaciones sociales. También se demuestra que los alumnos aumentaron su autoconciencia sobre el papel de los medios en sus vidas, y el profesorado comenzó a comprender mejor los intereses de sus alumnos, así como sus parámetros de consumo de Internet, mejorando sus habilidades para ayudar a los jóvenes a estar más alfabetizados mediáticamente.

  18. Costes asociados a las horas de cuidado informal de los mayores dependientes en un ámbito rural Costs associated to informal caregiving hours for older people living in rural communities [Spain

    Directory of Open Access Journals (Sweden)

    Pablo Moya Martínez

    2009-04-01

    Full Text Available Objetivos: Determinar el coste asociado a las variables que mejor predicen las horas de cuidado informal (CI en mayores residentes en su domicilio con algún grado de dependencia para las actividades de la vida diaria (AVD.Métodos: Estudio observacional transversal en 241 personas mayores de 64 años, de ámbito rural y de ambos sexos (un 37,8% hombres y un 62,2% mujeres. La media (desviación estándar de edad fue de 81,07 (7,01 años. Mediante el cuestionario RAI-HC (Resident Assessment Instrument Home Care se recogieron variables sociodemográficas, dependencia en AVD y horas de CI recibido. Se empleó el análisis de regresión lineal múltiple para determinar la relación existente entre la variable dependiente horas de CI y el total de variables independientes, sociodemográficas, de las actividades básicas de la vida diaria e instrumentales.Resultados: Las variables que mejor explican las horas de Cl son vivir solo, la necesidad de ayuda para comer, preparar comidas, moverse en la cama y salir a la calle, que representan el 46,3% de la variabilidad en la necesidad de horas de CI. Los coeficientes estandarizados mayores corresponden a las variables dependencia para comer (0,272 y para preparar las comidas (0,205. Ser dependiente para comer supone un incremento de 275 h de CI anual y un coste incremental asociado de 2.406,15 €/año. La dependencia para la preparación de comidas supone un incremento de 307,2h anuales y un coste incremental asociado de 2.688,18 €/año. La dependencia en función de las AVD tiene un coste de entre 4.972,72 y 21.479,15 € por año.Conclusiones: Casi la mitad del coste de las horas de CI que precisa una persona mayor con algún grado de dependencia se puede atribuir a vivir solo y a la necesidad de ayuda para un reducido grupo de AVD fáciles de evaluar, como comer, cocinar, moverse en la cama y salir a la calle.Objectives: To determine the costs associated with the variables that best predict hours of

  19. Adesão ao tratamento e controle da pressão arterial por meio da monitoração ambulatorial de 24 horas Blood pressure treatment adherence and control through 24-hour ambulatory monitoring

    Directory of Open Access Journals (Sweden)

    Guilherme Brasil Grezzana

    2013-04-01

    Full Text Available FUNDAMENTO: A hipertensão arterial sistêmica (HAS é um importante fator de risco cardiovascular, no entanto os níveis de controle pressórico persistem inadequados. A avaliação da adesão ao tratamento anti-hipertensivo com a utilização da monitoração ambulatorial da pressão arterial (MAPA de 24 horas pode representar um importante auxílio na busca de metas de controle da HAS. OBJETIVO: Avaliar a adesão ao tratamento anti-hipertensivo e a sua relação com os valores de PA obtidos pela MAPA de 24 horas entre pacientes hipertensos de centros de atenção primária à saúde (APS. MÉTODOS: Estudo transversal com 143 pacientes hipertensos de amostra representativa de serviço de APS do município de Antônio Prado, RS. Foi realizada aplicação do teste de Morisky e Green para avaliar a aderência ao tratamento e a verificação do número de medicamentos utilizados, seguida pela aplicação da MAPA de 24 horas. RESULTADOS: Observou-se que 65,7% da amostra foram considerados aderentes ao tratamento proposto, 20,3% eram moderadamente aderentes, enquanto somente 14% foram classificados como não aderentes. Do total de 143 pacientes avaliados, 79 (55,2% foram identificados como HAS controlada (130/80 mmHg, 103 (72% apresentaram ausência de descenso noturno da PA e 60 (41,9% não estavam controlados durante o período de vigília. CONCLUSÃO: Verificamos, no presente estudo, que não há um controle adequado da HAS, com consequente perda de oportunidade dos profissionais envolvidos na APS de ajuste adequado das metas de PA preconizados. Esse fato ocorre a despeito de apropriada adesão ao tratamento anti-hipertensivo dos pacientes vinculados ao ambulatório de APS.BACKGROUND: Although systemic arterial hypertension (SAH is an important cardiovascular risk factor, blood pressure level control often remains inadequate. Assessment of adherence to antihypertensive treatment through 24-hour ambulatory blood pressure monitoring (ABPM may

  20. Assessment of the impact of soil heating on soil cations using the degree-hours method Evaluación del impacto del calentamiento del suelo en los cationes del suelo utilizando el método de los grados-hora Avaliação do impacto do aquecimento térmico nos catiões do solo recorrendo ao método dos graus-hora

    Directory of Open Access Journals (Sweden)

    Nieves Barros

    2012-11-01

    Full Text Available Important factors in the evaluation of fire severity are the duration of the soil exposition to a certain temperature as well as the factors that determine the thermal transmissivity on the soil (moisture, texture, organic matter content, etc.. The aim of this work was to apply the degree-hours method (DH to characterize the thermal impact of forest fires in soils. Thermal treatments in the laboratory were conducted using soil samples in order to study the effects in the soil exchange complex. The results showed the effect of the supplied degree-hour (DH on the cation exchange capacity (CEC, which was expressed by a continuous exponential decrease in the CEC. This function may better explain the process of the decreasing of CEC than only the maximum temperature values. The sum of cations extracted in relation to the thermal treatment gradually increased with temperature or DH, and tended to stabilize at high values. The concentration of the different cations extracted increased gradually with the intensity of heating, and when related to the DH appeared to fit an equation of the type y=a+bxc with a high degree of confidence. Analyses of the results show that the measurement of the heat supplied to the soil is a useful parameter with which to interpret pedologic changes, especially when those changes happen continuously over time.Para la evaluación de la severidad de un incendio, tanto la duración de la exposición del suelo a una determinada temperatura como los factores que determinan la capacidad de transmisión térmica en el suelo (humedad, textura, contenido en materia orgánica, etc. son parámetros importantes a tener en cuenta. El presente estudio tiene como objetivo la aplicación de la metodología de los grados-hora (DH en la caracterización de los impactos térmicos de los incendios forestales en el suelo. Los tratamientos térmicos se realizaron en el laboratorio usando muestras de suelo recogidas en el campo sin alterar su

  1. Efeito do ibuprofeno administrado uma hora antes da inovulação de embriões bovinos Effect of ibuprofen administered one hour before the bovine embryo transfer

    Directory of Open Access Journals (Sweden)

    H.J. Narváez

    2010-06-01

    Full Text Available Avaliou-se o efeito do ibuprofeno administrado uma hora antes da inovulação de embriões bovinos, com o objetivo de melhorar a taxa de prenhez. Após a avaliação da resposta ao protocolo de sincronização do estro, 76 fêmeas selecionadas como receptoras de embriões foram distribuídas em três grupos (G experimentais: G1 (n=25 receptoras usadas como controle, G2 (n=30 receptoras que receberam ibuprofeno 5mg/kg, I.M, uma hora antes da inovulação dos embriões, e G3 (n=21 receptoras que receberam uma matriz polimérica de liberação controlada de ibuprofeno administrado por via subcutânea. As taxas de prenhez foram de 16% (4/25, 43,3% (13/30 e 14,2% (3/21, para G1, G2 e G3, respectivamente. Observou-se diferença (PThe effect of the administered ibuprofen was evaluated one hour before the embryo transfer of bovine embryos in order to improve pregnancy rates. After evaluating the response to protocol synchronization of estrus, 76 Females selected as the recipients of embryos were distributed into three experimental groups: G1 (n = 25 surrogate cows used as control, G2 (n = 30 surrogate cows that received 5mg/kg ibuprofen, IM, one hour before the embryo transfer, and G3 (n = 20 surrogate cows that received an array polymeric release of controlled ibuprofen subcutaneously administered. The pregnancy rates were 16% (4/25, 43.3% (13/30, and 14.2% (3/21 for G1, G2, and G3, respectively. There was statistical difference (P<0.024 on pregnancy rate of G2, in comparison with those of G1 and G3. The administration of ibuprofen intramuscularly one hour before the embryo transfer resulted in better pregnancy rate in Nellore surrogate cows.

  2. Efeitos agudos do exercício físico prolongado: avaliação após ultramaratona de 24 horas Acute effects of prolonged physical exercise: evaluation after a twenty-four-hour ultramarathon

    Directory of Open Access Journals (Sweden)

    Daniela Guinther Passaglia

    2013-01-01

    Full Text Available FUNDAMENTO: As consequências e os riscos do exercício físico contínuo por períodos prolongados não estão esclarecidos. OBJETIVO: Avaliar os efeitos do exercício prolongado em participantes de uma ultramaratona de 24 horas. MÉTODOS: Vinte corredores foram selecionados para avaliação, um dia antes e imediatamente após a prova em que os corredores devem percorrer a maior distância em 24 horas. Foram obtidos dados clínicos, laboratoriais e ecocardiográficos. RESULTADOS: A distância média percorrida foi de 140,3 ± 18,7 km. Os corredores apresentaram redução do peso corpóreo (p BACKGROUND: The consequences and risks of prolonged physical exercise are not well established. OBJECTIVE: To evaluate the effects of prolonged physical exercise on the participants of a 24-hour ultramarathon race. METHODS: Twenty male runners were selected for evaluation a day before and immediately after the race, where the athletes had to cover the most distance in 24 hours. Clinical, laboratory and echocardiographic data were obtained at both evaluations. RESULTS: Mean distance covered was 140.3 ± 18.7 km. Runners showed weight loss (p < 0.001 and decrease in systolic (p < 0.001 and diastolic (p = 0.004 blood pressure. Hematological changes were compatible with the physiological stress. Plasma levels of creatine phosphokinase strikingly increased post-race (163.4 ± 56.8 vs. 2978.4 ± 1921.9 U/L; p < 0.001 and was inversely correlated with distance covered: those who covered the longest distances showed the lowest CPK levels (Pearson r = 0.69, p = 0.02. After the race, 2 runners showed a slight increase in Troponin levels. One of them also had simultaneous decrease in left ventricular ejection fraction (coronary artery disease was subsequently ruled out. Basal echocardiography assessment had shown LV hypertrophy in one and increased left atrial volume in five runners. After the race, there was a decrease in E/A ratio (p < 0.01. CONCLUSION: Prolonged

  3. Efeitos agudos do exercício físico prolongado: avaliação após ultramaratona de 24 horas Acute effects of prolonged physical exercise: evaluation after a twenty-four-hour ultramarathon

    Directory of Open Access Journals (Sweden)

    Daniela Guinther Passaglia

    2012-01-01

    Full Text Available FUNDAMENTO: As consequências e os riscos do exercício físico contínuo por períodos prolongados não estão esclarecidos. OBJETIVO: Avaliar os efeitos do exercício prolongado em participantes de uma ultramaratona de 24 horas. MÉTODOS: Vinte corredores foram selecionados para avaliação, um dia antes e imediatamente após a prova em que os corredores devem percorrer a maior distância em 24 horas. Foram obtidos dados clínicos, laboratoriais e ecocardiográficos. RESULTADOS: A distância média percorrida foi de 140,3 ± 18,7 km. Os corredores apresentaram redução do peso corpóreo (p BACKGROUND: The consequences and risks of prolonged physical exercise are not well established. OBJECTIVE: To evaluate the effects of prolonged physical exercise on the participants of a 24-hour ultramarathon race. METHODS: Twenty male runners were selected for evaluation a day before and immediately after the race, where the athletes had to cover the most distance in 24 hours. Clinical, laboratory and echocardiographic data were obtained at both evaluations. RESULTS: Mean distance covered was 140.3 ± 18.7 km. Runners showed weight loss (p < 0.001 and decrease in systolic (p < 0.001 and diastolic (p = 0.004 blood pressure. Hematological changes were compatible with the physiological stress. Plasma levels of creatine phosphokinase strikingly increased post-race (163.4 ± 56.8 vs. 2978.4 ± 1921.9 U/L; p < 0.001 and was inversely correlated with distance covered: those who covered the longest distances showed the lowest CPK levels (Pearson r = 0.69, p = 0.02. After the race, 2 runners showed a slight increase in Troponin levels. One of them also had simultaneous decrease in left ventricular ejection fraction (coronary artery disease was subsequently ruled out. Basal echocardiography assessment had shown LV hypertrophy in one and increased left atrial volume in five runners. After the race, there was a decrease in E/A ratio (p < 0.01. CONCLUSION: Prolonged

  4. A la hora de escribir ensayos

    Directory of Open Access Journals (Sweden)

    Juan Alberto Blanco Puentes

    2006-01-01

    Full Text Available Hoy, los ejercicios académicos parten del escribir ensayos. Como género académico es útil tanto para escritores como para lectores; apaleando a lo anterior, el presente artículo tiene como tema de reflexión el Ensayo, y está encaminado a facilitar al lector la escritura de este tipo de textos, sin hacer diferencia –pero manteniendo la independencia de saberes– entre ciencias, estilos, temas e intenciones. De hecho, la estructura del texto, está diseñada para desarrollar el ejercicio de composición, permitiendo el acceso al tema desde sus antecedentes, su estructura formal, el lenguaje y el desarrollo del aprendizaje desde el ensayo.

  5. Es hora de un cambio. Entrevista motivacional

    OpenAIRE

    Fernández Morales, María Irene; Manzano Felipe, María de los Ángeles; Pérez García, Carmen

    2015-01-01

    Cartel presentado en la Segunda Conferencia Internacional de Comunicación en Salud, celebrada el 23 de octubre de 2015 en la Universidad Carlos III de Madrid Introduccion: la entrevista motivacional fue ideada por William Miller y Steve Rollnich en 1991, con la intención de trabajar la motivación, centrándose en el paciente, ayudándolo a resolver contradicciones sobre conductas o hábitos insanos y a desarrollar habilidades propias. Se trata de una “estrategia” de asistencia directa centrad...

  6. Combination Classes and "Hora de comunicacion."

    Science.gov (United States)

    Eldredge, Dee L.

    1989-01-01

    Ways to combine small classes of higher education students studying Spanish at various levels are described, including judicious use of language laboratories, staggering of the different level groups, and rotation of activities geared toward students' individual proficiency levels. (CB)

  7. Efecto de colutorio-gel de clorhexidina sobre el crecimiento de placa en 24 horas = Effect of chlorhexidine mouthrinses-gel on de novo plaque formation in 24 hours

    Directory of Open Access Journals (Sweden)

    Rivera, Tânia

    2006-01-01

    Full Text Available En un estudio cruzado, doble ciego y randomizado, 25 alumnos de Odontologia de buena salud oral, participaron de cuatro estudios donde ellos se abtuvieron de toda limpieza mecanica oral por 24 horas, los estudios estuvieron separados entre si por 4 semanas. Durante los estudios los alumnos en un randomizado orden, se enjuagaron por una vez con uno de los siguientes colutorios: CHX 0.12% + alcohol (Oralgene®, CHX 0.12% + alcohol (Perio.Aid®, CHX 0.1% + alcohol (Dentilim® y CHX 0.1% + HMC 2.5% (Colutoriogel®, nueva formula. Despues de un dia se midio formación de placa, se completo y registro el cuestionario de parametros clinicos. Las formulaciones de CHX 0.12% + alcohol y CHX 0.1% + HMC 2.5% se mostraron eficientes en retardar el crecimiento de placa dental de novo, esto obtenido de las observaciones clinicas, y siempre superior (p < 0.05 a la formulación del colutorio de CHX 0.1%+ alcohol (Dentilim®. Los resultados de este estudio demuestran el potencial clinico de este nuevo colutorio-gel sin alcohol de CHX 0.1% + HMC 2.5% (Colutoriogel® como un efectivo agente antiplaca y con reducidas efectos secundarios registrados

  8. A oralidade e a escritura na literatura infantil: referencial teórico para a hora do contoThe orality and the writing on child literature: theory to fairy tale time

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    Clarice Fortkamp Caldin

    2002-05-01

    Full Text Available Research on theoretical aspects of orality and writing. It presents a historical sketch of the narrators of tales and detaches the social function performed by the reader as co-author of tales. It increases the value of fairytales as cathartic and important to the development of the child psychism. It shows the commitment and the critic vision of Brazilian contemporary fairytales. It suggests an integration of librarians and teachers at the fairytale time.Aborda aspectos teóricos sobre a oralidade e a escritura. Apresenta um esboço histórico dos narradores de histórias e destaca seu papel social. Pressupõe o leitor como co-autor da obra literária. Valoriza os contos de fadas como catárticos e necessários ao desenvolvimento do psiquismo infantil. Mostra o compromisso com a verossimilhança e a visão crítica da brasilidade dos textos infantis contemporâneos. Sugere integração de bibliotecários e professores na Hora do Conto.

  9. An unusual Ni-Sb-Ag-Au association of ullmannite, allargentum, Au-rich silver and Au-bearing dyscrasite from Oselské pásmo “silver” Lode of Kutná Hora Pb-Zn-Ag ore district (Czech Republic)

    Czech Academy of Sciences Publication Activity Database

    Pažout, R.; Šrein, V.; Korbelová, Zuzana

    2017-01-01

    Roč. 62, č. 4 (2017), s. 247-252 ISSN 1802-6222 Institutional support: RVO:67985831 Keywords : ullmannite * allargentum * Au-rich silver * Au- bearing dyscrasite * chemistry * Kutná Hora ore district Subject RIV: DO - Wilderness Conservation OBOR OECD: Environmental sciences (social aspects to be 5.7) Impact factor: 0.609, year: 2016

  10. Apolo-Prometeu e Dioniso: dois perfis mitológicos do "homem das 24 horas" de Gaston Bachelard Apollo-Prometheus and Dionysus: two mythological profiles of Gaston Bachelard's "24-hour man"

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    Alexander de Freitas

    2006-04-01

    Full Text Available Gaston Bachelard (1884-1962, um filósofo como ele se auto-denomina de "dupla natureza", pensador de campos do conhecimento tão díspares como a epistemologia da ciência e a metafísica da imaginação poética, reclama uma leitura da dualidade e da complexidade da sua vida e obra. Desse modo, o objetivo deste artigo é investigar a relação dialógica entre a epistemologia da ciência e a metafísica da imaginação poética, dois delineamentos opostos, concorrentes e complementares da filosofia de Bachelard, freqüentemente expressos pelos epítetos "diurno" e "noturno". Para estudarmos a relação entre essas duas vertentes do pensamento de Bachelard, partimos da análise da ambivalência dos seguintes pares de conceitos: obstáculo epistemológico & imaginação material e psicanálise do conhecimento & método fenomenológico, que estruturam, teoricamente no primeiro par e, metodologicamente no segundo, sua epistemologia da ciência e sua metafísica da imaginação poética. Os dados obtidos permitem concluir que a sutura entre a epistemologia científica e a metafísica poética de Bachelard está representada em seu conceito de "homem das 24 horas". Esse homem complexo, andrógino, leitor e pensador das idéias científicas e da gênese poética, parece ser uma imagem conciliadora das antinomias expressas nas faces diurna e noturna da filosofia bachelardiana. Ampliando a análise imagética do "homem das 24 horas", por meio de uma hermenêutica mitanalítica, encontramos as duas faces da filosofia de Bachelard configuradas, respectivamente, pelos mitos de Apolo-Prometeu e Dioniso.Gaston Bachelard (1884-1962, a philosopher who declared himself to be of a "double nature", a thinker in fields of knowledge as diverse as the epistemology of science and the metaphysics of poetic imagination, demands a reading of the duality and complexity of his life and work. The purpose of this article is therefore to investigate the dialogical

  11. Avaliação do efeito analgésico preemptivo do lumiracoxibe comparado com placebo nas primeiras 24 horas de pós-operatório

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    Vilmar Molon

    Full Text Available OBJETIVO: Testar o lumiracoxibe, utilizado preemptivamente contra um placebo, e analisar o consumo de analgésicos (dipirona e tramadol nas primeiras 24h do pós-operatório. MÉTODOS: Sessenta pacientes submetidas à mamoplastia de aumento, sob anestesia peridural, foram selecionadas e divididas de forma randomizada em dois grupos - GI e GII. Sessenta minutos antes da operação, por via oral, as 30 pacientes do GI receberam um comprimido de lumiracoxibe 400mg, e as 30 do GII um comprimido de placebo. A dor pós-operatória foi avaliada através da escala analógica visual, graduada de 0 (sem dor a 10 (dor de maior intensidade, sendo aplicada sempre que houvesse referência de dor. Para escores obtidos iguais ou menores que 4, a paciente recebia 15mg/kg de dipirona, até máximo de um grama, via venosa. Para escores de 5, 6 ou 7, recebia 50mg de tramadol por via venosa. Escores de 8 ou mais eram tratados com 0,5mg/kg de meperidina endovenosa. RESULTADOS: Os escores obtidos no GI foram significativamente menores que os do GII dentro das primeiras 24 horas, resultando em consumo 20% menor de dipirona e 56% menor de tramadol. Da mesma forma, observou-se que o tempo para solicitação de analgésicos pela primeira vez no pós-operatório foi de 191 minutos maior no GI. CONCLUSÃO: O emprego do lumiracoxibe preemptivamente mostrou-se efetivo no combate à dor pós-operatória, reduzindo consideravelmente o consumo global de analgésicos nesse período e aumentando o tempo de solicitação de analgésico pela primeira vez.

  12. Refluxo laringofaringeano: estudo prospectivo correlacionando achados laringoscópicos precoces com a phmanometria de 24 horas de 2 canais Laringopharingeal reflux: prospective study that compare early laryngoscopic finds and 2 channel and 24 hours esophageal testing

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    O. Marambaia

    2002-08-01

    Full Text Available Introdução: Manifestações laríngeas do refluxo gastro-esofágico são problemas cada vez mais comuns. Estudos revelam alta associação com sensação de "globus", rouquidão crônica e com tosse crônica. Seu diagnóstico e tratamento diferem da clássica doença do refluxo gastro-esofágico. Os achados à endoscopia laríngea de hiperemia e edema de estruturas glóticas, espessamento do espaço interaritenóideo, granulomas, pólipos, edema de Reinke, estenose subglótica sugerem uma investigação diagnóstica completa através da pHmanometria de 24 horas, exame de maior sensibilidade e especificidade. Objetivo: correlacionar achados clínicos e laringoscópicos precoces sugestivos de refluxo gastro-esofágico com resultados da pHmanometria de 24 horas. Avaliar terapia medicamentosa e modificações dietéticas. Forma de estudo: Clínico prospectivo. Material e Método: pacientes adultos com queixas crônicas: tosse seca, "globus", sialorréia, disfonia, pigarro, halitose e engasgos. Foram excluídos pacientes com outras patologias de vias aéreas. Endoscopia laríngea descartava aqueles que apresentassem lesões laríngeas mais avançadas. Encaminhamento à pHmanometria e iniciado tratamento clínico. Resultados: 83,6% apresentaram refluxo patológico. Sintomas mais freqüentes: disfonia (72,5%, pigarro (60,8%, tosse (29,4%, "globus" (23,5% e sialorréia (19,6%. Associação de sintomas: dois (67,4%; três (41,2% e quatro (21,5%. 49 pacientes iniciaram tratamento com omeprazol (20 mg e dieta: 83,7% cursaram com melhora dos sintomas após 6 meses. Em 95,9% dos pacientes tratados houve melhora laringoscópica. Conclusões: Houve uma correlação importante entre história clínica e endoscopia laríngea com achados à pHmanometria de 24 horas. Outros estudos poderão fortalecer a telescopia laríngea para o diagnóstico do refluxo laringofaríngeo e seu acompanhamento. É necessária abordagem multidisciplinar, além de um aumento do grau

  13. Refluxo laringofaringeano: estudo prospectivo correlacionando achados laringoscópicos precoces com a pHmanometria de 24 horas de 2 canais Laringopharingeal reflux: prospective study that compare early laryngoscopic finds and 2 channel and 24 hours esophageal testing

    Directory of Open Access Journals (Sweden)

    O. Marambaia

    Full Text Available Introdução: Manifestações laríngeas do refluxo gastro-esofágico são problemas cada vez mais comuns. Estudos revelam alta associação com sensação de "globus", rouquidão crônica e com tosse crônica. Seu diagnóstico e tratamento diferem da clássica doença do refluxo gastro-esofágico. Os achados à endoscopia laríngea de hiperemia e edema de estruturas glóticas, espessamento do espaço interaritenóideo, granulomas, pólipos, edema de Reinke, estenose subglótica sugerem uma investigação diagnóstica completa através da pHmanometria de 24 horas, exame de maior sensibilidade e especificidade. Objetivos: correlacionar achados clínicos e laringoscópicos precoces sugestivos de refluxo gastro-esofágico com resultados da pHmanometria de 24 horas. Avaliar terapia medicamentosa e modificações dietéticas. Forma de estudo: clínico prospectivo randomizado. Método: 61 pacientes adultos com queixas crônicas: tosse seca, "globus", sialorréia, disfonia, pigarro, halitose e engasgos. Foram excluídos pacientes com outras patologias de vias aéreas. Endoscopia laríngea descartava aqueles que apresentassem lesões laríngeas mais avançadas. Encaminhamento à pHmanometria e iniciado tratamento clínico. Resultados: 83,6% apresentaram refluxo patológico. Sintomas mais freqüentes: disfonia (72,5%, pigarro (60,8%, tosse (29,4%, "globus" (23,5% e sialorréia (19,6%. Associação de sintomas: dois (67,4%; três (41,2% e quatro (21,5%. 49 pacientes iniciaram tratamento com omeprazol (20 mg e dieta: 83,7% cursaram com melhora dos sintomas após 6 meses. Em 95,9% dos pacientes tratados houve melhora laringoscópica. Conclusões: Houve uma correlação importante entre história clínica e endoscopia laríngea com achados à pHmanometria de 24 horas. Outros estudos poderão fortalecer a telescopia laríngea para o diagnóstico do refluxo laringofaríngeo e seu acompanhamento. É necessária abordagem multidisciplinar, além de um aumento do

  14. Reguladores de la brotación, alternativos a la cianamida hidrogenada, para suplir la falta de horas de frío en viñedos tropicales del litoral ecuatoriano

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    Raquel Herranz

    2015-12-01

    Full Text Available La cianamida hidrogenada (CH es un eficaz estimulante de la brotación de las yemas habitualmente utilizado en viticultura tropical, pero manipular esta materia activa conlleva un alto riesgo por su elevada toxicidad. Según algunos estudios tratamientos alternativos podrían llegar a producir sobre las yemas efectos similar a la CH, compensado la falta de horas de frío en viñedos situados en zonas tropicales, como los ubicados en la costa sur ecuatoriana. De entre todos los tratamientos evaluados destacan los efectos producidos por la aplicación directa sobre las yemas de peróxido de hidrógeno al 5%. Este tratamiento consigue estimular la brotación de la práctica totalidad de las yemas, adelantando e incrementando el desarrollo vegetativo y duplicando el rendimiento de las cepas, sin mermar la calidad de los racimos producidos. Por tanto podemos afirmar que los tratamientos con peróxido de hidrógeno son una alternativa viable, más económica y sostenible, a las aplicaciones de CH en estas condiciones de cultivo   Abstract Hydrogen cyanamide (CH is an effective stimulant bud breaking usually used in tropical viticulture, but handling this active substance carries a high risk because of their high toxicity. According to some studies alternative treatments could potentially produce a similar effect on the buds to CH, offset the lack of chilling hours in vineyards located in areas without a sufficient period of chilling hours, such as those located on the southern coast of Ecuador. Among all treatments evaluated the effects include direct application to the buds of hydrogen peroxide 5%. This treatment gets stimulate bud breaking of almost all of the buds, advancing and increasing vegetative growth and doubling the performance of the strains, without compromising the quality of the grapes produced. Therefore we can say that the hydrogen peroxide treatments are a viable, economical and sustainable, alternative to CH applications in these

  15. Monitorização eletrocardiográfica ambulatorial por 24-horas em cães com cardiomiopatia dilatada idiopática Twenty-four-hour ambulatory electrocardiographic monitoring in dogs with idiopathic dilated cardiomyopathy

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    F.L. Yamaki

    2007-12-01

    Full Text Available Caracterizou-se monitorização eletrocardiográfica ambulatorial por 24 horas (ou monitorização Holter em cães com cardiomiopatia dilatada idiopática, visando principalmente à detecção de arritmias ventriculares não detectadas pela eletrocardiografia convencional (de repouso. Para tanto, avaliaram-se 40 pacientes com diagnóstico de cardiomiopatia dilatada idiopática, por meio de exame físico e mensuração indireta da pressão arterial, além de exames eletrocardiográfico, ecocardiográfico, radiográfico de tórax e da monitorização Holter. Extra-sístoles ventriculares foram detectadas, por monitorização Holter, em 97,5% dos animais e taquicardia ventricular, em 45%. Não houve correlação entre o número de extra-sístoles ventriculares e a fração de encurtamento. Considerando as manifestações clínicas, apenas houve associação entre presença de taquicardia ventricular e histórico de síncopes. Conclui-se que a incidência de arritmias ventriculares em cães com cardiomiopatia dilatada idiopática é bastante alta, sendo a taquicardia ventricular relativamente freqüente, ocorrendo mais sob a forma não sustentada.This study aimed to characterize 24-hour ambulatory electrocardiographic monitoring (Holter monitoring in dogs with idiopathic dilated cardiomyopathy. Physical examination and indirect (Doppler blood pressure measurement, and also electrocardiography, thoracic radiography, echocardiography, and 24-hour ambulatory electrocardiographic exams were performed in 40 dogs with idiopathic dilated cardiomyopathy. Ventricular extrasystoles were detected in 97.5% of the animals, and ventricular tachycardia in 45%. No correlation between the number of ventricular extrasystoles and the shortening fraction was observed. Concerning the clinical symptoms, there was only association between the presence of ventricular tachycardia and past report of syncope. It was concluded that the incidence of ventricular arrhythmias is

  16. Atividade física, horas de assistência à TV e composição corporal em crianças e adolescentes Physical inactivity, TV-watching hours and body composition in children and adolescents

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    Ivan Romero Rivera

    2010-08-01

    Full Text Available FUNDAMENTO: Sedentarismo é fator predisponente ao aparecimento/piora de outros fatores de risco cardiovascular, particularmente obesidade. OBJETIVO: Estabelecer nível de atividade física (NAF e número diário de horas de TV (HTV e a associação e/ou correlação destas variáveis com faixa etária, sexo, classe econômica, escola pública/privada, excesso de peso e obesidade, em crianças/adolescentes. MÉTODOS: Estudo transversal, base populacional escolar, ensino público e privado, fundamental e médio. Cálculo da amostra baseado na menor prevalência esperada de inúmeras variáveis, incluindo sedentarismo. Amostragem por conglomerados. Protocolo: Questionário estruturado, incluindo "Physical Activity Questionaire for Older Children" (PAQ-C; medidas de peso, altura, índice de massa corporal (IMC e prega cutânea do tríceps (PCT. Análise estatística: Qui-quadrado; correlação linear. RESULTADOS: Nos 1.253 estudantes, com média de idade de 12,4 ± 2,9 anos, sendo 547 do sexo masculino, observou-se uma prevalência de sedentarismo em 93,5%, mais frequente em adolescentes do sexo feminino; não houve associação entre NAF e excesso de peso ou gordura corporal; futebol e dança foram as atividades mais frequentes em meninos e meninas, respectivamente; 60% dos estudantes não têm aulas de Educação Física. Média e mediana de HTV foram, respectivamente, 3,6 e 3 horas; houve associação significante entre maior HTV e obesidade e correlação significante entre NAF e idade (negativa e entre IMC e PCT (positiva. CONCLUSÃO: O sedentarismo está presente em 93,5% das crianças e adolescentes de Maceió, sendo mais prevalente nos adolescentes e no sexo feminino, não havendo associação ou correlação desta variável com excesso de peso ou gordura corporal; obesidade associou-se a > 3 HTV.BACKGROUND: Physical inactivity is a predisposing factor to the onset/worsening of other cardiovascular risk factors, particularly obesity

  17. OCORRÊNCIA E DURAÇÃO DAS TEMPERATURAS MÍNIMAS DIÁRIAS DO AR PREJUDICIAIS À FECUNDAÇÃO DAS FLORES DO ARROZ EM SANTA MARIA, RS: .II - ESTIMATIVA DO NÚMERO DIÁRIO DE HORAS COM TEMPERATURAS BAIXAS

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    Valduino Estefanel

    1991-12-01

    Full Text Available O presente trabalho objetivou testar os modelos analíticos utilizados por ANGELOCCI et al (1979, HELDWEIN (1983 e os propostos com ajustes para o verão de Santa Maria (Santa Maria, I, II e III para estimar o número diário de horas com temperatura do ar ≤ 10, 11, 12, 13, 14, 15, 16 e 17,0°C, para os meses de dezembro, Janeiro, fevereiro e março para Santa Maria, RS. A comparação entre os valores obtidos diretamente dos termogramas e os estimados por cinco modelos analíticos (ANGELOCCI et al, 1979; HELDWEIN,1983; Santa Maria I, II e III foi feita em função dos valores médios diários de horas dos dias com temperaturas baixas, coeficientes de determinação, linear e angular da equação de 1° grau entre os valores reais e os estimados. Verifica-se que é possível estimar, com precisão satisfatória, o número diário de horas com temperatura do ar ≤ 17, 16, 15, 14, 13 e 12,0°C, utilizando os modelos analíticos de ANGELOCCI et al (1979 e o Santa Maria III.

  18. Sundered Voices, Streets of Privilege: Lived-in Intricacies of the Japanese Colonial Empire in Korea and Manchuria

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    Kyu Hyun Kim

    2015-12-01

    Full Text Available Nayoung Aimee Kwon. Intimate Empire: Collaboration and Colonial Modernity in Korea and Japan. Durham, NC: Duke University Press, 2015. 296 pp. $90 (cloth, $25 (paper. Emer O'Dwyer. Significant Soil: Settler Colonialism and Japan's Urban Empire in Manchuria. Cambridge, MA: Harvard University Press, 2015. 528 pp. $60 (cloth. In the last decade, English-language studies of Japanese colonialism seem to have turned a new leaf. The book-length studies under review here... are two fine examples of the new types of scholarship tackling the problem of Japanese colonial empire. Kwon and O’Dwyer not only chart and navigate new territories in their respective scholarly subfields—late colonial Korean literature and Japanese colonial experiences in Northeast China—but also showcase new levels of sophisticated and thoughtful engagement with Korean- and Japanese-language historiography....

  19. A descriptive epidemiology of leisure-time physical activity in Brazil, 1996-­1997 Epidemiología descriptiva de la actividad física en horas libres en el Brasil, 1996­-1997

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    Carlos A. Monteiro

    2003-10-01

    between LTPA and socioeconomic status, measured either by income or schooling, independent of age, region, and urban or rural place of residence. CONCLUSIONS: The prevalence of adult LTPA in Brazil was much lower than the levels that have been reported for developed countries. However, the demographic and social distribution of LTPA in Brazil followed a pattern similar to the one usually observed in developed nations, where men tend to be more active than women, increasing age limits LTPA, and higher socioeconomic status is associated with more LTPA. Our data will provide a baseline to evaluate the impact on LTPA of "Agita Brasil" ("Move, Brazil", an initiative to encourage physical activity that was implemented in the country after 1997.OBJETIVOS: Describir la prevalencia, frecuencia, tipo, motivación y distribución demográfica y socioeconómica de la actividad física en horas libres (AFHL entre adultos en el Brasil. MÉTODOS: La fuente de datos para nuestro estudio fue la Encuesta para la Medición del Nivel de Vida (EMNV en el Brasil, que se llevó a cabo en 1996 y 1997. Mediante esta encuesta se estudió una muestra probabilística multietápica y estratificada de 4 893 hogares que abarcó a 11 033 personas de 20 años de edad o mayores. Los hogares encuestados se seleccionaron en la dos regiones más pobladas del Brasil, el Noroeste y el Sureste, donde viven 70% de todos los habitantes del Brasil. Las personas seleccionadas contestaron una serie de preguntas acerca de sus actividades físicas en horas libres. RESULTADOS: Sólo 13% de los brasileños encuestados indicaron que hacían un mínimo de 30 minutos de AFHL un día de la semana o más, y únicamente 3,3% indicó que lo hacía como mínimo 30 minutos durante 5 días de la semana o más, que es la cantidad recomendada. Entre las personas más jóvenes se encontró que los hombres eran más activos que las mujeres. No obstante, esta diferencia descendió notablemente a medida que aumentó la edad, de tal

  20. Del sueño americano a los sueños de ciudadanía : análisis de la campaña ¡Ya es hora! como elemento de apoyo en la definición de la ciudadanía estadounidense de origen latino

    OpenAIRE

    Tovar Pimentel, Adjani Gabriela

    2010-01-01

    Durante las últimas dos décadas del siglo XX, los flujos migratorios de AL a Estados unidos se incrementaron sustancialmente. Ante la falta de políticas claras en materia migratoria, desde distintas organizaciones de la sociedad civil, se han implementado acciones que buscan el respeto de los derechos del enclave cultural latino. Tal es el caso de la campaña ¡Ya es hora!, una campaña histórica apartidista, lanzada en respuesta a las movilizaciones de la comunidad latina, que buscó fomentar la...

  1. Disponibilidade de horas de frio na região central do Rio Grande do Sul: 2 - Distribuição geográfica Chilling hours in the central region of Rio Grande do Sul state: 2 - Geographic distribution

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    Galileo Adeli Buriol

    2000-10-01

    Full Text Available Foram traçadas as cartas da distribuição de disponibilidade de horas de frio na região Central do Rio Grande do Sul. Para tal, utilizaram-se os dados de disponibilidade de ocorrência do número médio acumulado de horas de frio Maps of chilling hours distribution in the central region of Rio Grande do Sul, Brazil, were drawn. Mean of chilling hours bellow 7°C (HF<7 and 13°C (HF<13 accumulating every 15 days up to certain date were used. Isolines of different intensities were drawn using average accumulated values of the number of chilling hours for the occurrence probability of 50%. Two distribution combinations were used to determine the occurrence probability of chilling hours. One was a discrete distribution to verify if there was chilling hours accumulated during the 15 day interval and the other one was a continuous distribution used to identify the accumulate chilling hours. Regression equations that adjusted chilling hours values as a function of the local latitude and altitude were used to simplify isolines drawing. Lower values of accumulate chilling hours below 7°C and below 13°C were observed in locals with low altitudes, such as Jacuí, Vacacaí and Ibicuí river valleys and main tributary streams. However, higher values were observed in high altitudes mainly in Serra do Sudeste and Planalto highland areas.

  2. Estimativa de horas de frio abaixo de 7 e de 13°C para regionalização da fruticultura de clima temperado no estado de São Paulo Temperate fruit crop zoning in the State of São Paulo - Brazil based upon estimated number of hours with temperature below 7 and 13°C

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    Mário J. Pedro Júnior

    1979-01-01

    Full Text Available Estimativa e mapeamento do número de horas com temperaturas abaixo de 7 e 13°C no Estado de São Paulo e análise comparativa do comportamento de fruteiras de clima temperado constituem os objetivos do presente trabalho. Foi cotado o número de horas com temperaturas inferiores a 7 e 13°C, índices considerados limites necessários à dormência dessas plantas. Foram selecionados termogramas de doze postos agrometeorológicos do Instituto Agronômico, situados em altitudes variáveis entre 25 e 1.000m, correspondentes ao período 1964-1973. Estabeleceram-se equações para estimativa do número de horas com temperaturas inferiores a 7°C (HF-7 e 13°C (HF-13 em função da temperatura média do mês de julho, cujos coeficientes de correlação foram de -0,88 e -0,93, respectivamente. Com base nessas equações foram mapeadas as isolinhas de HF-7 e HF-13 para o Estado de São Paulo, encontrando-se desde valores médios anuais de HF-7 inferiores a 20 horas, característicos das regiões de transição de clima mesotérmico a megatérmico do Planalto Ocidental e das regiões mais baixas do norte e oeste do Estado, até valores anuais de HF-7 superiores a 200 horas, característicos das áreas acima de 1.500 metros de altitude no Sul do Estado, na serra da Mantiqueira, limítrofe com Minas Gerais, e na serra do Mar, limítrofe com o Rio de Janeiro. Com base na introdução de diferentes frutíferas de clima temperado no Estado de São Paulo, verificou-se uma relação muito grande entre os índices HF-7 e HF-13 mapeados com o comportamento e potencialidade de exploração comercial.The behavior of temperate climate fruit crops in the State of São Paulo - Brazil as function of "dormancy units" (DAMARIO, 1969 was analysed with the object of providing a simple method for mapping areas with aptitude for commercial development of the crop trees. Thermographs from 12 agrometeorological stations located at altitudes varying from 25 to 1000 meters above

  3. Spinal cord injury: epidemiologycal study of 386 cases with emphasis on those patients admitted more than four hours after the trauma Trauma raquimedular: estudo epidemiológico de 386 casos com ênfase para aqueles pacientes admitidos após quatro horas do trauma

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    Manoel Baldoino Leal-Filho

    2008-06-01

    Full Text Available We studied 386 cases of spinal cord injury to analyze the follow up of the patients admitted most of the time more than four hours, the majority of the injuries happening far from the attending health service and first specialized care received long after the accident. This is a clinical study based on data collected during hospitalization of the patients, operated or not, in a Brazilian public health service. The lesion mainly seen was fracture and dislocation, isolated or on multiple levels, and the most important clinical complications were due to respiratory failure and hypotension, especially because 73.8% were from outside and they were admitted more then four hours after the trauma. The mortality rate was 11.9%, but just 2.1% had undergone a surgery. The complications resulted in major risk of death when the trauma was at the cervical level and the patients were over 50 years old, especially when admitted more than four hours after the trauma. We emphasize the importance of the first health care concerning the clinical treatment, aiming to reduce the mortality rate.Estudamos 386 casos de trauma raquimedular, observando a evolução dos pacientes admitidos na maioria das vezes após quatro horas do trauma, a maioria procedente de lugar distante do serviço de saúde. Trata-se de um estudo clínico baseado em dados coletados durante a hospitalização, de pacientes operados ou não, em serviço de saúde pública no Brasil. Na maioria das vezes a lesão principal foi fratura-luxação, isolada ou em múltiplos níveis, e as complicações clínicas mais importantes foram devido à insuficiência respiratória e hipotensão, especialmente porque 73.8% dos casos eram de lugares distantes, tendo sido admitidos mais de quatro horas após o trauma. A taxa de mortalidade foi 11,9%, sendo 2,1% em pós-operatório. As complicações resultaram em maior risco de morte quando o trauma foi ao nível cervical, idade acima de 50 anos, especialmente

  4. Taxa de concepção de cabras inseminadas com sêmen caprino resfriado a 5ºC, por 12 ou 24 horas, em meio diluidor à base de gema de ovo Conception rate of goats inseminated with semen cooled in egg yolk diluent at 5ºC, for 12 or 24 hours

    Directory of Open Access Journals (Sweden)

    A.P. Siqueira

    2009-02-01

    Full Text Available Avaliou-se a capacidade fecundante do sêmen caprino resfriado a 5ºC, por 12 (TI ou 24 horas (TII, em container especial. Para tanto, utilizaram-se 62 fêmeas e dois reprodutores (B1 e B2 da raça Toggenburg, distribuídos em um esquema fatorial 2x2 (dois reprodutores e dois períodos de estocagem do sêmen. Após a coleta, o sêmen foi diluído em Tris-frutose-gema de ovo a 2,5%, envasado em palhetas de 0,25mL, com 150x10(6 espermatozoides móveis e resfriado a 5ºC. As fêmeas receberam duas doses de 22,5µg de PGF2α, em intervalos de 10 dias para a sincronização do estro. A partir da primeira aplicação de PGF2α, as fêmeas foram monitoradas para ocorrência de estro, três vezes ao dia. Realizou-se uma única inseminação, pela técnica de fixação da cérvice, 12 horas após o início do estro. A motilidade e o vigor, após 12 ou 24 horas de resfriamento, foram de 66,14±0,11% e 62,50±0,05%, e 3,46±0,61 e 3,27±0,50, respectivamente. Não houve influência (P>0,05 do reprodutor, nem do período de armazenamento do sêmen sobre a taxa de concepção das cabras, que foi de 49,1%.The fertilizing capacity of goat semen cooled in egg yolk diluent at 5ºC, for 12 or 24 hours was evaluated. Sixty-two Toggenburg does and two sexually mature Toggenburg bucks were used in a fatorial treatment combination (two bucks and two storage periods. The semen was diluted in 2.5% Tris-frutose-egg yolk; envased in 0.25mL plastic straws, with 150x10(6 mobile spermatozoa; and cooled at 5ºC for 12 or 24 hours. The females received two doses of 22.5µg of prostaglandine F2α, at each 10-day intervals in order to synchronize the estrous. From the first PGF2α injection, estrous occurrence was monitored three times per day. Only one insemination was used, using the cervix fixation method, 12 hours after the estrous onset. The means of motility and strength, 12 (TI and 24 hours (TII after semen cooling at 5ºC, were 66.14±0.11% and 62.50±0.05%, and 3.46±0

  5. Efeitos do salbutamol e do formoterol sobre pressão arterial, frequência cardíaca e saturação de oxigénio em asmáticos, durante uma hora One hour effects of salbutamol and formoterol on blood pressure, heart rate and oxygen saturation in asthmatics

    Directory of Open Access Journals (Sweden)

    Geraldo Andrade Capuchinho-Júnior

    2008-06-01

    Full Text Available Objectivo: Analisar os possíveis efeitos do uso de β -2 -agonistas, de curta e longa duração, nas pressões arteriais sistólica (PAS e diastólica (PAD, na saturação parcial de oxigénio (SpO2 e na frequência cardíaca (FC, durante o período de uma hora. Material e métodos: Vinte e quatro doentes com asma persistente grave, em tratamento no ambulatório de Pneumologia do Hospital Universitário Gaffrée e Guinle, foram seleccionados para um ensaio clínico sequencial e cruzado. Os valores da PAS, PAD, SpO2 e FC foram registados antes e após o uso de broncodilatadores, salbutamol 400 µg e formoterol 12 µg, em dias diferentes, com intervalo mínimo de 24 horas. Resultados: Todos os doentes apresentaram distúrbio ventilatório obstrutivo, identificado pela redução da relação entre o volume expiratório forçado no primeiro segundo (VEMS e a capacidade vital forçada (CVF. Após o uso de substância broncodilatadora, não houve variação significativa nas PAS e PAD, nem na FC; porém, a SpO2 aumentou com o uso de salbutamol. Conclusão: Não foram observadas alterações hemodinâmicas significativas após o uso de salbutamol e formoterol nas doses preconizadas.Aim: To analyse systolic (SBP and diastolic blood pressure (DBP, partial oxygen saturation (SpO2 and heart rate (HR disorders for an hour after short and long acting ß2-agonists. Material and methods: Twenty-four severe persistent asthma Pulmonology outpatients at Hospital Universitário Gaffrée e Guinle were selected. SBP, DBP, SpO2 and HR values were determined before and after 400 µg of salbutamol and 12 µg of formoterol, on different days, with a minimum interval of 24 hours. Results: All patients showed ventilatory obstruction, as seen by a reduced FEV1/FVC ratio. There was no statistical SBP/DBP/HR difference after bronchodilator agents, but SpO2 increased with salbutamol. Conclusion: A standard dose of salbutamol and formoterol does not cause haemodynamic

  6. Determined of Rainfall Erosivity Indices (EI30, Lal, Hudson and Onchev for Namak Lake Basin

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    Z.T. Alipour

    2011-06-01

    Full Text Available In this research the indices EI30, AIm,‎ KE>1‎ as well as P/√t‎ were determined for 16 pluviograph as well as for 3 Namak Lake Basin nearby stations. Regression relationships were established between the dependent variables of EI30, AIm, KE>1‎ as well as P/√t‎ Indices and other easily accessible rainfall indices of: fournier, modified fournier, maximum monthly rainfall, maximum daily rainfall, standard deviation of monthly and annual rainfall as well as pluviometer site elevations. This made the establishment of appropriate relationships between rainfall intensity dependent indices and the dependent variable of rainfall intensity (at stations where intensity was non-existent possible. In the next step, the indices as well as easily accessible rainfall data from pluviograph stations were exploited to find out EI30 ,AIm ,‎ KE>1‎ as well as P/√t‎ indices, while using the previously obtained regression relationships.

  7. Determined of Rainfall Erosivity Indices (EI30, Lal, Hudson and Onchev) for Namak Lake Basin

    OpenAIRE

    Z.T. Alipour; M.H. Mahdian; S. Hakimkhani; M. Saeedi

    2011-01-01

    In this research the indices EI30, AIm,‎ KE>1‎ as well as P/√t‎ were determined for 16 pluviograph as well as for 3 Namak Lake Basin nearby stations. Regression relationships were established between the dependent variables of EI30, AIm, KE>1‎ as well as P/√t‎ Indices and other easily accessible rainfall indices of: fournier, modified fournier, maximum monthly rainfall, maximum daily rainfall, standard deviation of monthly and annual rainfall as well as pluviometer site elevations. This made ...

  8. Topographic Map of Quadrangle 3466, Lal-Sarjangal (507) and Bamyan (508) Quadrangles, Afghanistan

    Science.gov (United States)

    Bohannon, Robert G.

    2006-01-01

    This map was produced from several larger digital datasets. Topography was derived from Shuttle Radar Topography Mission (SRTM) 85-meter digital data. Gaps in the original dataset were filled with data digitized from contours on 1:200,000-scale Soviet General Staff Sheets (1978-1997). Contours were generated by cubic convolution averaged over four pixels using TNTmips surface-modeling capabilities. Minor artifacts resulting from the auto-contouring technique are present. Streams were auto-generated from the SRTM data in TNTmips as flow paths. Flow paths were limited in number by their Horton value on a quadrangle-by-quadrangle basis. Peak elevations were averaged over an area measuring 85 m by 85 m (represented by one pixel), and they are slightly lower than the highest corresponding point on the ground. Cultural data were extracted from files downloaded from the Afghanistan Information Management Service (AIMS) Web site (http://www.aims.org.af). The AIMS files were originally derived from maps produced by the Afghanistan Geodesy and Cartography Head Office (AGCHO). Because cultural features were not derived from the SRTM base, they do not match it precisely. Province boundaries are not exactly located. This map is part of a series that includes a geologic map, a topographic map, a Landsat natural-color-image map, and a Landsat false-color-image map for the USGS/AGS (Afghan Geological Survey) quadrangles covering Afghanistan. The maps for any given quadrangle have the same open-file number but a different letter suffix, namely, -A, -B, -C, and -D for the geologic, topographic, Landsat natural-color, and Landsat false-color maps, respectively. The open-file report (OFR) numbers for each quadrangle range in sequence from 1092 - 1123. The present map series is to be followed by a second series, in which the geology is reinterpreted on the basis of analysis of remote-sensing data, limited fieldwork, and library research. The second series is to be produced by the USGS in cooperation with the AGS and AGCHO.

  9. A crise do socialismo analisada no calor da hora

    Directory of Open Access Journals (Sweden)

    Reginaldo Benedito Dias

    2009-11-01

    Full Text Available O presente artigo demonstra como os acontecimentos que levaram à crise e desintegração dos países do bloco soviético foram analisados no calor dos acontecimentos, tomando como parâmetro os livros "Nós, o povo" e "A desintegração do monolito", selecionados por causa das diferentes perspectivas metodológicas e ideológicas que representam.  

  10. Raúl Castro a la hora de las decisiones

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    Janette HABEL

    2010-01-01

    Full Text Available Este artículo trata sobre el nuevo rol político de Raúl Castro en Cuba. Su misión no es fácil. Debe redefinir un proyecto de desarrollo viable en condiciones históricas y geopolíticas nuevas; garantizar la estabilidad del país; organizar el relevo entre los antiguos dirigentes históricos y las nuevas generaciones; y, además, iniciar negociaciones con la administración Obama. ¿Se podrá hablar en adelante de un «raulismo» o se seguirá imponiendo el «fidelismo»? Asimismo, ¿cómo salvaguardar la soberanía e independencia, junto a las principales conquistas sociales desde hace cincuenta años, mientras al mismo tiempo se llevan a cabo las reformas «estructurales » y se intenta normalizar relaciones con el continente, específicamente con Estados Unidos? Esa respuesta, que no es obvia, la debe dar Raúl Castro.

  11. RAÚL CASTRO A LA HORA DE LAS DECISIONES

    Directory of Open Access Journals (Sweden)

    Janette HABEL

    2009-01-01

    Full Text Available Este artículo trata sobre el nuevo rol político de Raúl Castro en Cuba. Su misión no es fácil. Debe redefinir un proyecto de desarrollo viable en condiciones históricas y geopolíticas nuevas; garantizar la estabilidad del país; organizar el relevo entre los antiguos dirigentes históricos y las nuevas generaciones; y, además, iniciar negociaciones con la administración Obama. ¿Se podrá hablar en adelante de un raulismo o se seguirá imponiendo el «fidelismo»? Asimismo, ¿cómo salvaguardar la soberanía e independencia, junto a las principales conquistas sociales desde hace cincuenta años, mientras al mismo tiempo se llevan a cabo las reformas «estructurales » y se intenta normalizar relaciones con el continente, específicamente con Estados Unidos? Esa respuesta, que no es obvia, la debe dar Raúl Castro.

  12. El reality show a la hora de la merienda

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    Lic. Rosa María Ganga Ganga

    2000-01-01

    Full Text Available Los programas de testimonio, inscritos dentro del género televisivo del Reality Show, son una variante del más amplio subgénero del Talk Show y tienen ya una cierta tradición en nuestro país. El presente trabajo se centrará en este tipo de programas de testimonio que basan su estrategia discursiva en la presentación y representación del relato autobiográfico del hombre o la mujer anónimos, integrándose de esta forma en las corrientes más recientes de la sociología y la historiografía, y persigue esclarecer algunas de sus características y funciones, especialmente su función socializadora, a través del mecanismo biográfico y del concepto de habitus tomado de Pierre Bourdieu.

  13. O epitélio respiratório em ratos Wistar após 48 horas de exposição contínua ao ruído de baixa frequência

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    Nuno A.A. Castelo Branco

    2003-11-01

    Full Text Available RESUMO: Em estudos anteriores, demonstrou-se que a exposição crónica de ratos Wistar a ruído de baixa frequência (RBF provoca o estabelecimento de lesões definitivas no epitélio respiratório. A existência de possíveis períodos refractários tornou-se matéria de grande interesse. Neste estudo avaliam-se as alterações do epitélio respiratório de ratos Wistar após uma exposição contínua a RBF. Doze ratos foram expostos a RBF contínuo durante 48 horas. Dez ratos de controlo, do mesmo grupo etário, foram mantidos nas mesmas condições mas em silêncio. Os animais foram tratados de acordo com a norma 86/609/ /CE. Após a exposição, 2 ratos foram imediatamente sacrificados e grupos de 2 foram sucessivamente sacrificados, respectivamente, após 6, 12, 24, e 48 horas e sete dias em silêncio. Fragmentos do epitélio respiratório foram processados para microscopia óptica electrónica de varrimento. Seis horas após o termo da exposição, era visível tumefação intensa e irregular das células e eram evidentes estruturas em roseta contendo células em escova rodeadas por células secretoras. Os cílios apresentavam-se alterados e as microvilosidades das células em escova estavam agrupadas e perdiam a distribuição uniforme típica e observada nos animais de controlo. Estes aspectos observavam-se nas horas seguintes, embora diminuindo gradualmente de intensidade. Sete dias após o termo da exposição, tanto os ratos de controlo como os ratos expostos e mantidos em silêncio apresentavam epitélios com características não distinguíveis. As lesões epiteliais do aparelho respiratório provocadas pela exposição ao RBF são reversíveis se forem respeitados períodos de recuperação.REV PORT PNEUMOL 2003; IX (6: 473-479 ABSTRACT: Previous studies show that exposure to low frequency noise (LFN

  14. Efeitos do salbutamol e do formoterol sobre pressão arterial, frequência cardíaca e saturação de oxigénio em asmáticos, durante uma hora

    Directory of Open Access Journals (Sweden)

    Geraldo Andrade Capuchinho-Júnior

    2008-05-01

    Full Text Available Resumo: Objectivo: Analisar os possíveis efeitos do uso de β-2 -agonistas, de curta e longa duração, nas pressões arteriais sistólica (PAS e diastólica (PAD, na saturação parcial de oxigénio (SpO2 e na frequência cardíaca (FC, durante o período de uma hora.Material e métodos: Vinte e quatro doentes com asma persistente grave, em tratamento no ambulatório de Pneumologia do Hospital Universitário Gaffrée e Guinle, foram seleccionados para um ensaio clínico sequencial e cruzado. Os valores da PAS, PAD, SpO2 e FC foram registados antes e após o uso de broncodilatadores, salbutamol 400 μg e formoterol 12 μg, em dias diferentes, com intervalo mínimo de 24 horas.Resultados: Todos os doentes apresentaram distúrbio ventilatório obstrutivo, identificado pela redução da relação entre o volume expiratório forçado no primeiro segundo (VEMS e a capacidade vital forçada (CVF. Após o uso de substância broncodilatadora, não houve variação significativa nas PAS e PAD, nem na FC; po-rém, a SpO2 aumentou com o uso de salbutamol.Conclusão: Não foram observadas alterações hemo-dinâmicas significativas após o uso de salbutamol e formoterol nas doses preconizadas.Rev Port Pneumol 2008; XIV (3: 353-361 Abstract: Aim: To analyse systolic (SBP and diastolic blood pressure (DBP, partial oxygen saturation (SpO2 and heart rate (HR disorders for an hour after short and long acting ß2-agonists.Material and methods: Twenty-four severe persistent asthma Pulmonology outpatients at Hospital Universitário Gaffrée e Guinle were selected. SBP, DBP, SpO2 and HR values were determined before and after 400 μg of salbutamol and 12 μg of formoterol, on different days, with a minimum interval of 24 hours.Results: All patients showed ventilatory obstruction, as seen by a reduced FEV1/FVC ratio. There was no statistical SBP

  15. Comparison of microbial load in immersion chilling water and poultry carcasses after 8, 16 and 24 working hours Comparação da carga microbiana em águas de pré-resfriamento e carcaças de frangos, após jornadas de trabalho de 8, 16 e 24 horas

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    Ricardo Cavani

    2010-07-01

    Full Text Available Poultry processing facilities are known for using a great amount of water, which is mainly used on carcasses chilling stage. In Brazil, meat regulations state that each chiller tank must be emptied, cleaned and sanitized every 8 working hours. The aim of the current study was to assess the microbial load of chiller water used in poultry immersion chilling system after 8, 16 and 24 working hours in order to evaluate the reduction of water changes and chiller sanitization. Conventional physicochemical and microbiological assays were done in water supply samples (n=69 to suppress interferences caused by freshwater addition; pre chilled (n=345 post chilled carcasses (n=345 and chiller water samples of the last stage (n=69. The results showed no significant differences on microbial load samples between the three shifts suggesting that the proposed reduction may be secure and reduces the volume of wastewater that would impact the environment, besides improving the rational use of processing time.As atividades dos estabelecimentos de abate de frangos são conhecidas por utilizarem grandes volumes de água durante seus processos, principalmente no processo de resfriamento das carcaças de frangos. Parte desse volume utilizado se faz necessário, em cumprimento à legislação que determina que cada tanque do sistema de pré-resfriadores contínuos por imersão deve ser completamente esvaziado, limpo e desinfetado no final de cada período de trabalho (oito horas. O objetivo deste estudo foi comparar a carga microbiana das águas do sistema de resfriamento e das carcaças de frango ao final de oito, dezesseis e vinte e quatro horas de trabalho do abatedouro, para possível redução do número de vezes do completo esvaziamento dos tanques do sistema de resfriamento. Foram avaliadas, por meio de métodos convencionais microbiológicos e físico-químicos, amostras da água de abastecimento (n=69, visando a evitar possível interferência nas contagens das

  16. Protocolo de actuación preventiva para riesgo debido a alteraciones del ritmo circadiano en médicos de urgencias que trabajan en turnos de 24 horas Preventive action protocol for risk due to circadian rhythm disturbances in emergency physicians working in 24 hours shifts

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    Loreto Fillat de Acosta

    2009-12-01

    Full Text Available La autora analiza la situación patológica de los médicos de urgencias con turnos de 24 horas que alteran el ritmo circadiano, el estudio describe las condiciones de trabajo que afectan el ritmo biológico sueño-vigilia y las tareas intelectuales y de habilidades mecánicas desempeñadas por este personal, los daños a prevenir (accidentes in itinere, accidentes por manipulación de material biológico, enfermedades somáticas y psíquicas y el riesgo para los pacientes. Se propone un protocolo de actuación preventiva que abarca la mayor parte del trabajo, cuándo actuar, revisión de recursos, actuaciones a realizar en una unidad de salud laboral y sistema de comunicación al resto del hospital, Servicio de Prevención de Riesgos Laborales y Sistema Nacional de Salud.The author analyzes the pathological situation concerning to emergency physicians with 24-hour shifts which disturb their circadian rhythms, the study describes the working conditions that affect the biological sleep-wake rhythm and intellectual tasks and mechanical skills performed by these staff, damage to be prevented (commuting accidents, accidents caused by handling of biological material, somatic and psychic diseases and the risk to patients. After that, it's developed a proposal of preventive action protocol covering most of the work and finally when to act, available resources and actions to be taken in an occupational health unit, in addition to the communication system to the rest of the hospital, Occupational and Hazard Preventive Service and the National Health System.

  17. Pituitary-dependent hyperadrenocorticism in a shi tzu dog treated with twice-daily oral trilostane: a case reportHyperadrenocorticismo hipófise dependente em um cão shi tzu tratado com trilostane oral a cada 12 horas: relato de caso

    Directory of Open Access Journals (Sweden)

    Lucas Alécio Gomes

    2012-10-01

    trilostane com trilostane, via oral, a cada 12 horas, e o teste de estimulação com ACTH foi realizado em intervalo não usual durante o período de monitoração inicial (a cada 30 dias. Neste caso, a dose inicial de trilostane não demonstrou melhora em relação às alterações cutâneas e houve necessidade de aumento na dosagem.

  18. Disponibilidade de horas de frio na região central do Rio Grande do Sul: 1 - Ocorrência de valores acumulados para diferentes níveis de probalidade Chilling hours in the central region of Rio Grande do Sul state: 1 - Occurrence of accumulated values for different levels of probability

    Directory of Open Access Journals (Sweden)

    Arno Bernardo Heldwein

    2000-10-01

    Full Text Available Determinaram-se as disponibilidades de horas de frio abaixo de 7°C (HFThe availability of chilling hours below 7°C (HF<7 and 13°C (HF<13 accumulated every 15 days up to certain date for different levels of probability (1, 10, 20, 50, 80, 90 and 99% in 9 different locations in the central region of Rio Grande do Sul, was determined. Daily chilling hours were measured with thermographes or estimated by minimum and maximum daily temperatures and temperature at 9 pm adapting an analytical method or by multiple regression analysis. A combination of two distributions was used in order to determine the probability of occurring chilling hours. The first was a discrete distribution employed to verify whether there were chilling hours within the interval of 15 days and the other was a continuous distribution to verify the number of chilling hours when occurring. The availability of accumulated chilling hours expected for a given probability was calculated based on the density of gamma distribution. Normal distribution was used only in few cases in which the "g" parameter of the gamma function was greater than 27. It was observed that at least in one of every two years there are above 75 accumulated HF<7 up to June 30 in all locations. The availability of accumulated chilling hours from April, 1st up to September, 15th in 50% of all years varied from 200 HF<7 and 1250 HF<13 in Cachoeira do Sul to 490 HF<7 and 1850 HF<13 in Sobradinho. It was also observed that the variability of chilling hours occurrence among years is large on all locations and the relative difference among the availability of the different locations is proportionally greater at HF<7 than at HF<13. Availability of accumulated chilling hours during April is very low for HF<7, but it is considerable at HF<13. The number of chilling hours decreases drastically from the first 15 days to the last 15 days of September in all locations.

  19. Determinación del perfil metabólico mediante la cuantificación de parámetros clínicos y de laboratorio antes del procedimiento, en las primeras 24 horas y durante los tres meses posoperatorios en pacientes sometidos a liposucción de moderado volumen

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    Francisco Fabián Eraso

    2008-11-01

    Full Text Available ANTECEDENTES: el incremento de la grasa abdominal, tanto visceral como subcutánea, está asociado al desarrollo del síndrome metabólico que conlleva un riesgo aumentado de desarrollar diabetes, hipertensión y dislipidemia aterogénica. Con esta premisa, la liposucción podría teóricamente producir beneficios en el perfil metabólico y clínico, tendientes a disminuir dichos riesgos. Diseñamos este estudio para determinar los cambios en el perfil metabólico y los parámetros clínicos producidos en individuos no obesos. MÉTODOS: este es un estudio prospectivo descriptivo, llevado a cabo en 19 pacientes sometidos a liposucciones inferiores a 5.000 mL. Se hicieron mediciones del índice de masa corporal (IMC, perímetro abdominal, frecuencia cardiaca (FC y tensión arterial (TA y mediciones de laboratorio (perfil lipídico, ionograma, glicemia, hemoglobina, creatinina, albúmina, tiempo de protrombina antes de la cirugía, tres veces durante las primeras 24 horas, al mes y por último a los tres meses. RESULTADOS: las modificaciones de las variables se presentaron en diferentes momentos durante el seguimiento. Las variables clínicas perímetro abdominal e IMC mostraron una disminución estadísticamente significativa de 6,26 cm (p = 0,00 y 1,19 (p = 0,0052, respectivamente, que persistió hasta el final del estudio. En el posoperatorio temprano se presentó una disminución significativa de la albúmina (0,67mg/dL y de la hemoglobina con recuperación de los valores previos al mes. Los electrólitos medidos no tuvieron ninguna variación con significancia clínica aunque el potasio mostró una disminución con significancia estadística en el posoperatorio inmediato (0,31 y 0,23 meq/L, p = 0,02. El perfil lipídico no sufrió cambios significativos a largo plazo en este estudio y las variables clínicas de FC y TA, así como la creatinina y el tiempo de protrombina no mostraron ninguna variación. CONCLUSIÓN: de este estudio se concluye

  20. Índices de vegetação no milho em função da hora do dia e da taxa de nitrogênio aplicada Vegetation indices in the maize as a function of hour of the day and the applied rate of nitrogen

    Directory of Open Access Journals (Sweden)

    Eduardo G. Souza

    2009-12-01

    Full Text Available Métodos têm sido propostos visando à melhoraria da administração de nitrogênio (N e, simultaneamente, ao aumento de produtividade com a proteção do meio ambiente, diminuindo a concentração de nitratos no solo e na água, em que um deles, a agricultura de precisão, consiste na aplicação localizada dos insumos agrícolas em função da necessidade específica local. Neste contexto, a medição da reflectância espectral foliar da planta se apresenta como método promissor para o sensoriamento instantâneo da deficiência de N em milho, através do cálculo de índices de vegetação; entretanto, não são bem conhecidas as características da interação das plantas com a radiação solar. Avaliou-se, neste trabalho, o comportamento dos índices de vegetação em relação à hora do dia e da taxa de nitrogênio aplicada. Seis índices diferentes foram estudados: relação infravermelho próximo/vermelho (IVP/V, relação infravermelho próximo/verde (IVP/Verde, índice de vegetação de diferença normalizada (IVDN, índice verde de vegeta��ão da diferença normalizada (IVVDN, índice de vegetação ajustado ao solo (IVAS e índice aperfeiçoado de vegetação ajustado ao solo (IAVAS. Quando analisados apenas os dados coletados em torno do meio dia solar, os índices que apresentaram a menor dispersão dos resultados foram o IVDN e o IAVAS, enquanto para dados tomados durante todo o dia os índices que indicaram melhor explicação da variabilidade foram o IVAS e o IAVAS.Methods have been proposed seeking to improve the application of nitrogen (N simultaneously with yield increase and environmental protection, reducing the nitrate concentration in the soil and in the water. One of these methods, precision agriculture consists of the site-specific application of the agricultural inputs as a function of the local need. In this context, the measurement of the spectral leaf reflectance shows itseif as a promising method for the

  1. Anthropologische Charakteristik und morphologische Ähnlichkeit der Individuen aus dem Gräberfeld Kutná Hora-Karlov (okr. Kutná Hora/CZ)

    Czech Academy of Sciences Publication Activity Database

    Maxová, E.; Velemínský, P.; Likovský, Jakub

    2011-01-01

    Roč. 58, č. 2 (2011), s. 417-465 ISSN 0076-2741 Institutional research plan: CEZ:AV0Z80020508 Keywords : La Tène period * anthropology * morphology Subject RIV: AC - Archeology, Anthropology, Ethnology

  2. 'Cada día atrasamos el reloj un cuarto de hora para llegar con la hora americana'. Diario de viaje hacia el exilio

    OpenAIRE

    Bocanegra Barbecho, Lidia

    2015-01-01

    Muchos exiliados republicanos emigraron a América Latina después de la Segunda Guerra Mundial, desde Francia y por sus propios medios. Algunos se exiliaron a América por falta de trabajo en Francia, otros por miedo a una Tercera Guerra Mundial. Corrían tiempos duros en una Europa diezmada por los azotes de una guerra y por el inicio de las tensiones políticas en el concierto internacional que daría lugar a la Guerra Fría. En esta tesitura, un electricista con compromisos políticos en su tierr...

  3. Informe sobre la actividad física en horas libres y en horas de trabajo en la población estadounidense

    Directory of Open Access Journals (Sweden)

    2003-10-01

    Full Text Available A recent report that bears the title Physical Activity Among Adults: United States, 2000 describes one of the few studies in the world that quantify total daily energy expenditure among adults in a given population. Most studies that attempt to assess the level of physical activity performed by a country's inhabitants look at leisure-time physical activity or energy expenditures while on the job. By looking at just one of those two areas, such studies provide only a partial view of the overall physical activity levels within a population. The report on the adult population of the United States of America, which is based on the National Center for Health Statistic's National Health Interview Survey for the year 2000, draws on data obtained through approximately 39 000 household interviews, covering a total of more than 100 000 individuals from all 50 states. In essence, indicators were developed, based on frequency and duration, for regular leisure-time physical activity (exercise, sports, or active hobbies as well as for the amount of "usual daily activity" (i.e., commuting, performing household chores, running errands, and engaging in other activities not performed during leisure time. Regular leisure-time physical activity was thus defined as light or moderate activity for a minimum of 30 minutes per session at least five times a week, or intense activity for a minimum of 20 minutes per session at least three times a week. Light or moderate activity was defined as activity lasting at least 10 minutes that caused light sweating and a slight to moderate increase in breathing or heart rate. Vigorous activity was defined as activity lasting at least 10 minutes that caused heavy sweating or large increases in breathing or heart rate. In the case of "usual daily activity," its magnitude was determined by the number of times a day an individual had to walk or to lift or carry light, moderate, or heavy loads. These two indicators-regular leisure-time physical activity and usual daily activity-were combined to obtain an indicator for "overall physical activity level." According to results, 19% of U.S. adults engage in a high level of physical activity, with men being more likely than women to engage in such activity. In both sexes, however, the level of physical activity declines with age, so that adults in the oldest age group (65 or older were about five times as likely as adults in the youngest age group (18­24 years to never be physically active. Women were also more likely than men to never engage in physical activity. One in every 4 adults in the United States engages in little physical activity or none. Those who are more active in their usual daily activities are also more likely to engage in regular physical activity during leisure time. Almost three fourths of adults lift or carry light to heavy loads during their usual activities. The report also examines the association between various socioeconomic and demographic variables and physical activity. Adults with incomes below the poverty level are three times more likely to be physically inactive than adults in the highest income group (4 times the poverty level or more. Around 15% of Hispanics, 14% of blacks, and 20% of whites engage in a high level of physical activity. In terms of education, individuals having an advanced degree are almost twice as likely as individuals without a high school diploma to have a high level of physical activity. In short, the report described herein provides an accurate assessment of overall physical activity among U.S. adults and identifies high-risk population subgroups that should be the target of health promotion activities geared toward increasing physical activity levels. The data it includes will be the basis for monitoring progress toward achieving the 2010 national health objectives for physical activity among adults in the United States.

  4. Informe sobre la actividad física en horas libres y en horas de trabajo en la población estadounidense

    Directory of Open Access Journals (Sweden)

    2003-01-01

    Full Text Available A recent report that bears the title Physical Activity Among Adults: United States, 2000 describes one of the few studies in the world that quantify total daily energy expenditure among adults in a given population. Most studies that attempt to assess the level of physical activity performed by a country's inhabitants look at leisure-time physical activity or energy expenditures while on the job. By looking at just one of those two areas, such studies provide only a partial view of the overall physical activity levels within a population. The report on the adult population of the United States of America, which is based on the National Center for Health Statistic's National Health Interview Survey for the year 2000, draws on data obtained through approximately 39 000 household interviews, covering a total of more than 100 000 individuals from all 50 states. In essence, indicators were developed, based on frequency and duration, for regular leisure-time physical activity (exercise, sports, or active hobbies as well as for the amount of "usual daily activity" (i.e., commuting, performing household chores, running errands, and engaging in other activities not performed during leisure time. Regular leisure-time physical activity was thus defined as light or moderate activity for a minimum of 30 minutes per session at least five times a week, or intense activity for a minimum of 20 minutes per session at least three times a week. Light or moderate activity was defined as activity lasting at least 10 minutes that caused light sweating and a slight to moderate increase in breathing or heart rate. Vigorous activity was defined as activity lasting at least 10 minutes that caused heavy sweating or large increases in breathing or heart rate. In the case of "usual daily activity," its magnitude was determined by the number of times a day an individual had to walk or to lift or carry light, moderate, or heavy loads. These two indicators-regular leisure-time physical activity and usual daily activity-were combined to obtain an indicator for "overall physical activity level." According to results, 19% of U.S. adults engage in a high level of physical activity, with men being more likely than women to engage in such activity. In both sexes, however, the level of physical activity declines with age, so that adults in the oldest age group (65 or older were about five times as likely as adults in the youngest age group (18­24 years to never be physically active. Women were also more likely than men to never engage in physical activity. One in every 4 adults in the United States engages in little physical activity or none. Those who are more active in their usual daily activities are also more likely to engage in regular physical activity during leisure time. Almost three fourths of adults lift or carry light to heavy loads during their usual activities. The report also examines the association between various socioeconomic and demographic variables and physical activity. Adults with incomes below the poverty level are three times more likely to be physically inactive than adults in the highest income group (4 times the poverty level or more. Around 15% of Hispanics, 14% of blacks, and 20% of whites engage in a high level of physical activity. In terms of education, individuals having an advanced degree are almost twice as likely as individuals without a high school diploma to have a high level of physical activity. In short, the report described herein provides an accurate assessment of overall physical activity among U.S. adults and identifies high-risk population subgroups that should be the target of health promotion activities geared toward increasing physical activity levels. The data it includes will be the basis for monitoring progress toward achieving the 2010 national health objectives for physical activity among adults in the United States.

  5. Muscular damage, changes of heart rate, lactate and rating of perceived exertion in a relay race for ultra-endurance of 24 hours. Destrucción muscular, modificaciones de frecuencia cardiaca, lactato y percepción subjetiva de esfuerzo en una prueba de carrera por relevos de ultra-resistencia de 24 horas./Muscular damage, changes of heart rate, lactate and rating of perceived exertion

    Directory of Open Access Journals (Sweden)

    F. Navarro

    2010-09-01

    Full Text Available

    The aim of this study is to examine changes in the heart rate, blood lactate and creatinkinase (ck concentration and perceived effort (RPE before, during and after a race of 24 hours per relay. We analyzed the 8 subjects (33 ± 6.9 years, 172.6 ± 3 cm, 69.3 ± 8.7 kg participating in the race Ruta de la Plata was to travel the 340 km separating Castillo de las Torres (Sevilla and Baños Montemayor (Cáceres did relay 20 'in length during the race. . Four samples were taken during the race. The results show that Ck increased significantly during the race. Lactate concentration had a peak in the second sample (5.3 ± 2.4 mmol / l and after this sample was maintained at values close to 4 mmol / l (4.1 ± 1.6 mmol / l in the 3rd sample, and 4.3 ± 1.5 mmol / l in the last sample. Heart rate averaged 150.5 ± 20.6 p / m presenting a maximum value on the second sample (169 ± 8.7 p / m and from this down to the last sample. RPE values decreased in the course of the competition.
    Key Words:
    Heart rate, lactate, RPE, creatinkinase, ultraendurance

     

    Este trabajo pretende estudiar los cambios en la frecuencia cardiaca, la concentración sanguínea de lactato, creatinkinasa (Ck y la percepción subjetiva de esfuerzo (RPE antes, durante y después de una carrera de ultraresistencia de 24 horas por relevos. Se analizaron los 8 sujetos (33±6.9 años; 172.6±3 cm, 69.3±8.7 kg, participantes en la prueba deportiva Reto de la Plata que consistía en recorrer los 340 km que separan Castillo de las Torres (Sevilla y Baños de Montemayor (Cáceres haciendo relevos de 20’ de duración durante la prueba. Se realizaron cuatro tomas de muestras a lo largo de la prueba. Los resultados muestran como la Ck aumento significativamente a lo largo de la prueba, que la concentración de lactato tuvo un pico en la segunda

  6. A study to assess the domestic violence in mental illness & normal married women

    Directory of Open Access Journals (Sweden)

    Jyoti Srivastava, Indira Sharma, Anuradha Khanna

    2014-07-01

    Full Text Available Background: Domestic violence against women is the most pervasive human rights violation in the world today. According to UNiTE to End Violence against Women (2009 by UN Women, In the United States, one-third of women murdered each year are killed by intimate partners. In South Africa, a woman is killed every 6 hours by an intimate partner. The Objective: To assess the magnitude and causes of domestic violence with mental illness & normal women. Material & Methods: The sample of study comprised of 50 women with mental illness and 50 normal women. Mental illness patients diagnosed according to with Axis one psychiatric Disorder DSM IV-TR, who were selected from the Psychiatry OPD and ward of the S.S. Hospital, BHU and normal women were be selected from the accompany with patients of Sir Sunder Lal Hospital. The patients were assessed on the structured questionnaire on Domestic Violence. Results – The domestic violence present in married women with mental illness was 72% and normal women were 36%. Perceived causes of domestic violence in married women with mental illness were more compared to those with normal women. The health care personnel should be given an opportunity to update their knowledge regarding domestic violence and there is need education for domestic violence and cessation, so that they can help the women to protect/prevent domestic violence.

  7. IMPACT OF NUTRITIONAL COUNSELLING ON BODY MASS INDEX (BMI AND NUTRIENT INTAKE OF THE NON - COMMUNICABLE DISEASE PATIENTS (NCD

    Directory of Open Access Journals (Sweden)

    Manisha Singh

    2011-12-01

    Full Text Available Good health is an important discussion of the quality of life. Health problem is a major concern in all over the world but especially in developing countries. Non-communicable diseases ( NCDs contribute the ill health. Diabetes, coronary heart disease, various forms of cancer, gastro intestinal disorder and various diseases of bones and joints are diet related NCDs. Nutritional counselling is one of the effective tools of changing the food habits of people. The data for this study is taken from the out patients services of Department of Endocrinology & Metabolism and Cardiology of Sir Sunder Lal Hospital, Banaras Hindu University, Varanasi-5. Total 250 samples were included in the study. Age group 40 – 60 years were considered as study samples who attended the Endocrinology and Cardiology departments. Purposive sampling method was used in the study. Questionnaire cum interview method was adopted in the study. Anthropametric measurements were taken by using standard techniques. 24 hours diet recall method was also used in this study. Evaluation of councelling was done on basis of changes in BMI and nutrient intake. Result shows the positive impact of nutritional counselling in BMI and nutrient intake of NCD patients.

  8. É hora de investirmos em intervenções comportamentais computadorizadas no Brasil?

    Directory of Open Access Journals (Sweden)

    Henrique Pinto Gomide

    2013-06-01

    Full Text Available Intervenções comportamentais computadorizadas apresentam evidências de eficácia para diversas condições de saúde, como transtornos de ansiedade ou de humor e abuso do uso de álcool e tabagismo. Embora apresentem efeitos relativamente pequenos, elas podem atingir um grande número de usuários simultaneamente e funcionar de forma ininterrupta. Os objetivos do presente estudo foram: 1 analisar criticamente as evidências de eficácia presentes na literatura sobre intervenções comportamentais computadorizadas; 2 avaliar o potencial de utilização no país; 3 descrever a regulamentação existente; e 4 apresentar ferramentas para desenvolvimento destas intervenções através de uma revisão narrativa da literatura. As intervenções comportamentais computadorizadas se configuram como uma potencial ferramenta para a saúde pública, devido ao crescimento do uso de computadores e internet no Brasil e ao baixo custo de seu desenvolvimento.

  9. Ciencia de las Emociones: Llego la hora de llegar a todos.

    Directory of Open Access Journals (Sweden)

    Federico Fros Campelo

    2013-12-01

    Full Text Available Es realmente emocionante el momento de nuestra historia que vivimos. Precisamente ahora que estamos encontrando verdaderos fundamentos sobre el funcionamiento de nuestras emociones. La exploración neuropsicológica de los últimos 30 años maduró a tal punto que, como especie humana, ya conseguimos adoptar una perspectiva más precisa sobre nuestros sentimientos y sobre cómo se conforman. Nuestro conocimiento moderno sobre las emociones ya no es tan nebuloso como antes. Así, en este momento contamos con herramientas prácticas para entendernos mejor a nosotros mismos, manejarnos mejor, y llevarnos mejor con los demás.

  10. IMAGENS NO CALOR DA HORA OU A FÊNIX RENASCIDA DA IMAGEM DOCUMENTAL

    Directory of Open Access Journals (Sweden)

    Kati Caetano

    2008-12-01

    Full Text Available Apesar da freqüente discussão, tanto nos meios acadêmicos quanto nos midiáticos, envolvendo a crise da imagem documental, na esteira da propalada crise da cultura documental como um todo, não há como negar a proliferação de imagens e o incremento de uma produção assumida com esse propósito no universo das relações comunicacionais, seja ele impresso ou digital. Se, no domínio da arte, a ação hegemônica contemporânea consiste na desestabilização figurativa das imagens, do lado das mídias de produção massiva, afirma-se a sua estabilização como condiçãofundante do ato de documentar. Este trabalho não visa abordar as várias concepções de documental, porque parte do pressuposto de que esse aspecto se apresenta como resultado de estratégias figurativo-enunciativas de “fazer crer”, responsáveis por múltiplos regimes de sentido. De suas escolhas e agenciamentos decorrem modalidades interacionais amparadas na mediatez ou imediatez dos processos compreensivos, num sistema de valores condicionantes do ato comunicativo que coloca em evidência as funções prática, cognitiva, afetiva ou fiduciária (calcada em regimes de crençadas mediações simbólicas. A questão mais geral que norteia opresente texto é indagar como as diferentes mídias, do fotográfico ao virtual, operam com essas imagens e que tipos de implicações comunicacionais promovem.

  11. Imagens no calor da hora ou a Fênix renascida da imagem documental

    Directory of Open Access Journals (Sweden)

    Kati Caetano

    2008-12-01

    Full Text Available Apesar da freqüente discussão, tanto nos meios acadêmicos quanto nos midiáticos, envolvendo a crise da imagem documental, na esteira da propalada crise da cultura documental como um todo, não há como negar a proliferação de imagens e o incremento de uma produção assumida com esse propósito no universo das relações comunicacionais, seja ele impresso ou digital. Se, no domínio da arte, a ação hegemônica contemporânea consiste na desestabilização figurativa das imagens, do lado das mídias de produção massiva, afirma-se a sua estabilização como condição fundante do ato de documentar. Este trabalho não visa abordar as várias concepções de documental, porque parte do pressuposto de que esse aspecto se apresenta como resultado de estratégias figurativo-enunciativas de “fazer crer”, responsáveis por múltiplos regimes de sentido. De suas escolhas e agenciamentos decorrem modalidades interacionais amparadas na mediatez ou imediatez dos processos compreensivos, num sistema de valores condicionantes do ato comunicativo que coloca em evidência as funções prática, cognitiva, afetiva ou fiduciária (calcada em regimes de crença das mediações simbólicas. A questão mais geral que norteia o presente texto é indagar como as diferentes mídias, do fotográfico ao virtual, operam com essas imagens e que tipos de implicações comunicacionais promovem.

  12. De crisis y transformaciones. Los partidos políticos en la hora actual

    Directory of Open Access Journals (Sweden)

    Melina Andrea Deangeli

    2015-09-01

    Full Text Available Los partidos políticos han constituido un objeto de estudio privilegiado en la ciencia política. Desde las últimas décadas del siglo xx, existe una suerte de consenso sobre la crisis de estos en las democracias occidentales. El presente trabajo retoma aquellos diagnósticos para problematizar el lugar de los partidos políticos en la actualidad. Basándonos, principalmente, en el caso argentino, sostenemos que la transformación en el modelo de Estado propuesto y ejecutado en nuestro país a partir del año 2003 habría asumido implicancias concretas en la configuración de (algunos de ellos que, en consonancia con el contexto político, asumen nuevas dinámicas que implican la inclusión de miembros y demandas de diferentes espacios políticos como agrupaciones político-territoriales, movimientos sociales y organizaciones de la sociedad civil. Se analizan brevemente, además, los casos de Brasil, Bolivia y España.

  13. Sono e adolescência: quantas horas os adolescentes precisam dormir?

    OpenAIRE

    Pereira,Érico Felden; Barbosa,Diego Grasel; Andrade,Rubian Diego; Claumann,Gaia Salvador; Pelegrini,Andreia; Louzada,Fernando Mazzilli

    2015-01-01

    Objetivo Determinar a especificidade e a sensibilidade de uma medida para apontar o melhor ponto de corte para a duração de sono como preditor da sonolência diurna excessiva em adolescentes. Métodos Participaram do estudo 1.359 adolescentes, com idades de 14 a 21 anos, de duas cidades do sul do Brasil, que responderam a questionário de hábitos de sono e sonolência diurna. Utilizou-se a Receiver Operating Characteristic para estimar a capacidade preditiva da ...

  14. Ciencia de las Emociones: Llego la hora de llegar a todos.

    OpenAIRE

    Federico Fros Campelo

    2013-01-01

    Es realmente emocionante el momento de nuestra historia que vivimos. Precisamente ahora que estamos encontrando verdaderos fundamentos sobre el funcionamiento de nuestras emociones. La exploración neuropsicológica de los últimos 30 años maduró a tal punto que, como especie humana, ya conseguimos adoptar una perspectiva más precisa sobre nuestros sentimientos y sobre cómo se conforman. Nuestro conocimiento moderno sobre las emociones ya no es tan nebuloso como antes. Así, en este momento conta...

  15. In hora mortis. Devoción, espiritualidad y actitudes de los reyes ante la muerte

    Directory of Open Access Journals (Sweden)

    Andrea Martignoni

    2012-03-01

    Full Text Available ¿Cómo se prepara, se vive y se pone en escena el último trance de los reyes del siglo XII entre Francia y España? Para contestar a ese interrogante se privilegian en especial modo las fuentes relacionadas a la historia de dos guras reales importantes: Luís IX y Jaime I. Se analizan entonces los comportamientos, los gestos, las palabras, los lugares y los protagonistas que participaron a la ritualización de los últimos instantes de vida buscando de llevar a la luz las singularidades atinentes al cuerpo y al destino postmortem de un rey.

  16. Validación del método LAL para determinar endotoxinas bacterianas en el inyectable heparina sódica

    OpenAIRE

    Nancy Burguet; Lázaro César Brito

    2012-01-01

    Dentro del control de la calidad de los productos farmacéuticos, la United State Pharmacopeia establece la cuantificación de endotoxinas bacterianas por el método de lisado de amebocito de Limulus , como monitor de pirógenos para más del 90% de los parenterales que regula. Este método se aplicó de forma específica a vacunas bacterianas y virales, agentes antineoplásicos, radiofármacos y parenterales que se producen en la industria médico farmacéutica. En el presente trabajo se mostró la metod...

  17. Validación del método LAL para determinar endotoxinas bacterianas en el inyectable heparina sódica

    Directory of Open Access Journals (Sweden)

    Nancy Burguet

    2012-12-01

    Full Text Available Dentro del control de la calidad de los productos farmacéuticos, la United State Pharmacopeia establece la cuantificación de endotoxinas bacterianas por el método de lisado de amebocito de Limulus , como monitor de pirógenos para más del 90% de los parenterales que regula. Este método se aplicó de forma específica a vacunas bacterianas y virales, agentes antineoplásicos, radiofármacos y parenterales que se producen en la industria médico farmacéutica. En el presente trabajo se mostró la metodología a seguir para realizar la validación de la técnica de determinación de endotoxinas bacterianas por el método de gelificación. Para ello se confirmó la sensibilidad del reactivo utilizado (0,03125 UE/mL y la validez de los analistas para poder obtener resultados confiables. Las pruebas preliminares para el producto ensayado, heparina sódica 5000 UI/mL, demostraron que este producto no potencia ni inhibe la reacción del reactivo. Se escogió la dilución de trabajo (1/128 para la validación del método. De esta manera quedaron estandarizadas las condiciones para la validación del test de lisado de amebocito de Limulus por gelificación en este producto parenteral, método que se hace extensivo a la determinación de endotoxinas bacterianas en vacunas y en otros medicamentos por vía de administración intravenosa.

  18. Hyperspectral surface materials map of quadrangle 3466, La`l wa Sar Jangal (507) and Bamyan (508) quadrangles, Afghanistan, showing iron-bearing minerals and other materials

    Science.gov (United States)

    King, Trude V.V.; Hoefen, Todd M.; Kokaly, Raymond F.; Livo, Keith E.; Giles, Stuart A.; Johnson, Michaela R.

    2013-01-01

    This map shows the spatial distribution of selected iron-bearing minerals and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. This map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Goethite and jarosite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  19. Kundernes adfærd og indtag på en fastfood restaurant

    DEFF Research Database (Denmark)

    Lassen, Anne Dahl; Thomsen Volhøj, Klaus; Gross, Gitte

    2013-01-01

    De fleste danskere opfatter fastfood som usund mad. Den opfattelse passer godt med det generelle billede fra burgerrestauranter, pizzeriaer og maden på tankstationer. Det er som regel muligt at tage et sundere valg, men de sundere valg er ikke altid gjort synlige og attraktive for kunderne. I en ...

  20. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Mangala Sunder Krishnan. Articles written in Journal of Chemical Sciences. Volume 119 Issue 5 September 2007 pp 417-422. Effective Floquet Hamiltonian for spin = 1 in magic angle spinning NMR using contact transformation · Manoj Kumar Pandey Mangala Sunder ...

  1. Valores de glicemia durante las primeras 24 horas de vida en el recién nacido

    OpenAIRE

    Bejarano de Rodríguez, Nancy; Buenahora Tobar, Liliana; Gamba de Briceño, Margoth

    2010-01-01

    La transición en el metabolismo de los carbohidratos, desencadenada por el acto de nacer, tiene una base biológica en la cual se cambia la fuente de suministro de nutrientes: esto es, al feto soportado por el traspaso placentario de ellos y al recién nacido que abruptamente debe afrontar la evidencia del autoabastecimiento. Este proceso se encuentra regulado desde el punto de vista hormonal, por un complejo conformado por la relación de Insulina-Glucagón- Catecolaminas-Somatostatina-...

  2. Valores de glicemia durante las primeras 24 horas de vida en el recién nacido

    Directory of Open Access Journals (Sweden)

    Gamba de Briceño Margoth

    1990-12-01

    Full Text Available

    La transición en el metabolismo de los carbohidratos, desencadenada por el acto de nacer, tiene una base biológica en la cual se cambia la fuente de suministro de nutrientes: esto es, al feto soportado por el traspaso placentario de ellos y al recién nacido que abruptamente debe afrontar la evidencia del autoabastecimiento. Este proceso se encuentra regulado desde el punto de vista hormonal, por un complejo conformado por la relación de Insulina-Glucagón- Catecolaminas-Somatostatina-Glucosa, cuyo mecanismo no está del todo entendido. El propósito de la secreción de estas hormonas es mantener el balance energético indispensable para garantizar la integridad biológica del neonato, en especial del sistema nervioso central. Esta acción hormonal es la culminación de un proceso ontogénico iniciado in útero, el cual culmina extrauterinamente, como modulador de los nutrientes y de la actividad enzimática.

  3. BUSY: Una plataforma para la gestión de reservas por hora en PyMes

    OpenAIRE

    González Cabrero, Juan Carlos

    2016-01-01

    El objetivo de este proyecto consiste en el desarrollo de una plataforma software enfocada a pequeñas y medianas empresas (PyMEs), para llevar a cabo la organización de servicios ofrecidos a los clientes. buSy es una herramienta cómoda y sencilla para la gestión de reservas y control de horarios con un ámbito de negocio generalista, ya que su enfoque global permite la utilización de esta aplicación a una amplia gama de categorías de empresa. Se trata de un proyecto web desar...

  4. ¿Es hora de usar indicadores refinados para estudiar la fecundidad en América Latina?

    Directory of Open Access Journals (Sweden)

    Wanda Cabella

    Full Text Available Resumen El artículo discute la pertinencia de los llamados indicadores refinados de fecundidad para evaluar el nivel de la fecundidad en los países de América Latina. La principal ventaja de estos indicadores es su capacidad de identificar cuánto del cambio en la tasa global de fecundidad se debe a cambios en la intensidad y cuánto a cambios en el calendario. Los países de muy baja fecundidad están culminando un proceso de postergación de la maternidad que solo pudo ser descrito adecuadamente una vez que surgieron estos indicadores. A pesar de que en América Latina hay indicios de que en algunos países se comienza a procesar la postergación de la fecundidad, es aún muy limitada la capacidad de elaborar indicadores refinados y no abunda la discusión sobre sus virtudes, desventajas y potencialidades. Con la intención de sistematizar la acumulación al respecto y fomentar el debate, en este artículo se presentan las principales características de estas medidas y se discute cuáles indicadores serían los más adecuados para evaluar las tendencias de la fecundidad en la región y cómo podrían difundirse de modo de evitar equívocos en su interpretación. Nuestra principal conclusión es que a corto plazo resulta más urgente contar con indicadores de intensidad y calendario por orden de nacimiento que apelar a medidas sintéticas refinadas.

  5. Relojes Circadianos y Premio Nobel: hora de tomarse unos minutos para hablar de ritmos biológicos

    Directory of Open Access Journals (Sweden)

    Luis Fernando Larrondo Castro

    2018-01-01

    Full Text Available El Nobel 2017 en Fisiología o Medicina recayó en la descripción molecular de los relojes circadianos. A pocas semanas de haberse hecho el anuncio, uno de los recipientes de esta distinción, Michael Rosbash, visitó Chile. En estas breves páginas comentamos parte de su charla y destacamos la importancia que tienen los ritmos circadianos en la biología de los organismos, así como su impacto en salud y enfermedad.

  6. Governo: um aliado nem sempre lembrado pelas empresas na hora de desenvolver as atividades de P&D

    Directory of Open Access Journals (Sweden)

    Manoela Silveira dos Santos

    2011-10-01

    Full Text Available Pelo menos três agentes - o governo, a indústria e as instituições de ensino e pesquisa - devem atuar solidariamente na criação e no desenvolvimento do conhecimento. Mesmo com características distintas, devem atuar de forma cooperada para que os ganhos se multipliquem e estendam pela cadeia produtiva. Na sociedade do conhecimento, investir em P&D é quase que uma imposição para que haja desenvolvimento econômico e social. O governo brasileiro tem sido, por muito tempo, o responsável pela maior parte dos investimentos em P&D, no entanto hoje existem diversas iniciativas para estimular o investimento privado em P&D. Os objetivos deste trabalho são discutir as principais iniciativas do governo brasileiro, nos últimos 10 anos, que influenciarão no desenho das atividades de P&D no país, a fim de obter uma melhor compreensão acerca do papel do governo na promoção do P&D. A análise conjunta dos marcos institucionais possibilita perceber a força transformadora que provocarão no cenário, o que não seria possível se vistos isoladamente. Este artigo buscou convergir estas iniciativas para obter uma melhor compreensão acerca do papel do governo na promoção do P&D. Pode-se observar que o governo brasileiro é um importante parceiro para as empresas interessadas em investir em P&D; no entanto, muitas delas não o veem nesta posição.

  7. Educación para el Ocio: Ha llegado la hora de un nuevo objetivo para una vieja idea.

    Directory of Open Access Journals (Sweden)

    Susan Hutchinson

    2012-01-01

    Full Text Available La Educación para el Ocio nos sitúa ante una vieja idea, que está siendo examinada con renovado vigor en Canadá. Profesionales e investigadores de diversas disciplinas (por ejemplo, en el ámbito de Salud, la Justicia, la Educación o la Recreación reconocen, cada vez más, que son muchas las personas que pueden beneficiarse del ocio y de las oportunidades de recreación en sus comunidades, aún cuando son bastantes las no pueden hacerlo porque carecen de alfabetización en ocio. Esto es, de los conocimientos, habilidades y confianza que se necesitan para darle un significado personal, que incida positivamente en su bienestar y calidad de vida. La Educación para el Ocio es un medio clave para mejorar la alfabetización en ocio. El texto presenta un modelo de educación para el ocio desarrollado por la Dra. Brenda Robertson, argumentando cómo y por qué la Educación para el Ocio es necesaria para abordar la salud mental y el bienestar de las personas que sufren marginación en sus comunidades. Complementariamente se presentan algunas recomendaciones para avanzar esta Educación, como un componente fundamental de la agenda nacional para la recreación en Canadá.--------------------------------------------------------------------Leisure education is an old idea that is being examined with renewed vigour in Canada. Practitioners and researchers from various disciplines (e.g., health, justice, education, recreation are recognising anew that many people who could benefit from leisure or recreation opportunities in their communities are unable to do so because they lack leisure literacy. Leisure literacy refers to the knowledge, skills and confidence to engage in personally meaningful, health-enhancing leisure. Leisure education is a key means to enhance leisure literacy. The paper presents a model of leisure education developed by Dr. Brenda Robertson and argues for how and why leisure education is needed to address the mental health and well-being needs of persons who experience marginalisation in their communities. Recommendations for moving forward with leisure education as part of a national agenda for recreation in Canada are presented.

  8. Use of solar energy to condition system the science library in University of Valencia; Empleo de energia solar en el sistema de climatizaciond e lal biblioteca de ciencias de la Universitat de Valencia

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Amo, J. L.; Tena, F.; Martinez-Lozano, J. A.; Utrillas, M. P.

    2004-07-01

    This work represents a preliminary approach to the study of the possibilities of the renewable energy use for the air conditioning system installed in the Science Library of the University of Valencia. In the first part we will calculate the thermal necessities of the building and the feasibility of the installation of a solar photovoltaic system. We have considered two different solar systems in our study. One of them trying to generate the maximun solar energy possible taking into account space possibilities. The other is based on the electric energy delivery on electric company obtaining a considerable economical saving. (Author)

  9. Activities on superconductivity cavities at the IPN Orsay, in collaboration with: LAL-CNRS/IN2P3, Orsay; CEA-DAPNIA/SEA, Gif-sur-Yvette; DESY, Hamburg

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    Different topics concerning superconducting cavity resonators are overviewed. Field emission phenomena and surface effects are discussed in detail. Thermometers, cryostats and radiation mapping instruments are also concerned. 6 items are indexed separately for INIS database. (K.A.).

  10. Activities on superconductivity cavities at the IPN Orsay, in collaboration with: LAL-CNRS/IN2P3, Orsay; CEA-DAPNIA/SEA, Gif-sur-Yvette; DESY, Hamburg

    International Nuclear Information System (INIS)

    1995-01-01

    Different topics concerning superconducting cavity resonators are overviewed. Field emission phenomena and surface effects are discussed in detail. Thermometers, cryostats and radiation mapping instruments are also concerned. 6 items are indexed separately for INIS database. (K.A.)

  11. JCSC_129_11_1761_1769_SI.docx

    Indian Academy of Sciences (India)

    rahulwatile

    SUPPLEMENTARY INFORMATION. Synthesis of Quinoxaline Derivatives from Terminal Alkynes and o-phenylenediamines by using Copper Alumina Catalyst. AKHIL V NAKHATE, KALIDAS B RASAL, GUNJAN P DESHMUKH, SHYAM SUNDER R GUPTA and MANNEPALLI LAKSHMI KANTAM* ...

  12. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    phenylenediamines by using copper alumina catalyst · AKHIL V NAKHATE KALIDAS B RASAL GUNJAN P DESHMUKH SHYAM SUNDER R GUPTA LAKSHMI KANTAM MANNEPALLI · More Details Abstract Fulltext PDF. An efficient method for the synthesis ...

  13. International Journal of Engineering, Science and Technology - Vol ...

    African Journals Online (AJOL)

    Enhancement of heat transfer using varying width twisted tape inserts · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S Naga Sarada, AV Sita Rama Raju, K Kalyani Radha, L Shyam Sunder ...

  14. Food in Motion

    DEFF Research Database (Denmark)

    Andreassen, Pernille

    Projektet 'Mad i bevægelse' er et treårigt projekt, som er udarbejdet af Kræftens Bekæmpelse og blev påbegyndt i 2005. Projektets overordnede formål har været at skabe mulighed for et sundere madvalg for børn og unge inden for idrætten, samt at stimulere udviklingen af en sundere madkultur i idræ...

  15. O PAPEL DE DUAS SESSÕES EXTENUANTES COM DIFERENTES INTERVALOS ENTRE AS SESSÕES – 24 e 48 HORAS – E O EFEITO PROTETOR DA CARGA

    Directory of Open Access Journals (Sweden)

    Rodrigo Bergome Muniz

    2014-02-01

    Full Text Available It is reported that a single session of resistance exercise provides to our bodies with an adaptation of shape subsequent exercises do not have the same effect stressful. Objective: To evaluate the repeated bout effect in exercise sessions with different intervals after a week of the first session. Materials and Methods: 14 men (18 to 30 years engaged in strength training for a minimum of 6 months were divided into two groups A and B. The participants performed five sets, maximum repetitions with two minutes of rest between sets at 85% 1RM in biceps curl exercise unilateral Scott on the bench with the non-dominant arm. The second training session was performed 24 h later, for group A, and 48 hours later for group B. Blood samples were collected in pre measures, 24h, 48h, 72h and 96h, arm girth measurements, range of motion in flexion and extension, and measures of subjective perception of pain on palpation and by extension, before and after exercise every day of the tests. Results: When the first two exercise sessions were performed with shorter rest intervals (24 hours due to increased pain sensation, maintaining range of motion and reduced activity for longer serum CK higher. Conclusion: Exercises with short intervals (24 hours may modulate the repeated bout effect increasing the values of physiological variables and significant reductions in joint range of motion.

  16. La hora de la decisión. ¿Cómo logró “Merkozy” establecer las bases para una nueva Europa?

    Directory of Open Access Journals (Sweden)

    Andreas Rinke

    2011-11-01

    Full Text Available Los países de la zona euro vivieron durante 2011 algunos de los meses más dramáticos desde la creación del euro llegando transitoriamente a su fin con la política del eje franco-alemán que produjo un cambio en la arquitectura de la Unión Europea. El viejo debate sobre la “Europa de los círculos concéntricos” o de un “núcleo Europa” dejó de ser una teoría y se convirtió en realidad: el grupo de los 17 países de la eurozona se dio a partir de ese momento un nuevo marco. El presente texto señala, desde la óptica alemana, qué sucedió durante todos estos meses, reconstruye cómo cambió la posición de la canciller Angela Merkel ante la crisis económica, pasando de una actitud defensiva a una actitud ofensiva de respuesta, y muestra cómo finalmente esto llevó, con el apoyo decisivo del entonces mandatario francés Nicolás Sarkozy, a una transformación institucional importante al interior de la Unión Europea.

  17. Zvířecí skelet z laténského objektu v Nových Dvorech, okr. Kutná Hora

    Czech Academy of Sciences Publication Activity Database

    Kyselý, René

    2011-01-01

    Roč. 63, č. 2 (2011), s. 253-255 ISSN 0323-1267 Institutional research plan: CEZ:AV0Z80020508 Keywords : ritual * La Tène period * osteology * Bos taurus * cattle Subject RIV: AC - Archeology, Anthropology, Ethnology

  18. Hora do Herói:incidências de mutações culturais no brincar contemporâneo e implicações na aprendizagem

    OpenAIRE

    Soares, Leila da Franca

    2014-01-01

    Esta tese trata de uma investigação, de natureza qualitativa, sobre a incidência de mutações culturais no brincar contemporâneo da criança de quatro a cinco anos e suas implicações na aprendizagem. Para alcançar esse objetivo, a autora realiza, primeiramente, uma pesquisa bibliográfica, contemplando referências da Antropologia, Sociologia, Filosofia e Psicanálise, além de outras da área da Educação Infantil, as quais lhe permitem discutir alguns conceitos fundamentais ao desenv...

  19. La provisión de cuidados informales a las personas con discapacidad: Horas de cuidados y participación en el mercado laboral

    OpenAIRE

    Oscar D. Marcenaro-Gutiérrez; Rocío de la Torre Díaz; Mónica Domínguez-Serrano

    2012-01-01

    Resumen: En este trabajo se analiza el perfil de las personas que proporcionan cuidados informales a personas con discapacidad en Andalucía –en comparación con el resto de España-, y se evalúa cómo la atención a estas personas condiciona las posibilidades de las mujeres en el mercado de trabajo. Los resultados permiten afirmar que la fuerte feminización de la atención a las personas con discapacidad afecta de forma significativa a sus posibilidades laborales constriñendo las oportunidades d...

  20. Nález mince města Sikyon ze Svaté Kateřiny (okr. Kutná Hora)

    Czech Academy of Sciences Publication Activity Database

    Militký, Jiří

    2013-01-01

    Roč. 27, č. 1 (2013), s. 106-108 ISSN 0546-9414 R&D Projects: GA ČR GA13-24707S Institutional support: RVO:67985912 Keywords : Bohemia * Greece * Sikyon * triobolus/hemidrachm * coin import Subject RIV: AC - Archeology, Anthropology, Ethnology

  1. Migraciones internacionales, crisis económica mundial y políticas migratorias. ¿Llegó la hora de retornar?

    Directory of Open Access Journals (Sweden)

    Suzanne d’Anglejan

    2009-11-01

    Full Text Available La crisis económica mundial del 2008 dio lugar a una aceleración del debate migratorio en los principales países de destino. En medio de la debacle macroeconómica de los países de la OCDE, entre los cuales se encuentran los principales países receptores de los flujos de migración internacional, la mano de obra inmigrante fue duramente golpeada. Sin embargo, su mayor vulnerabilidad no se tradujo en unas políticas más favorables. Al contrario, se multiplicaron los argumentos anti-inmigración y manifestaciones xenófobas, creando el espacio político para una serie de nuevas leyes de restricción y represión a la inmigración: reformas a lo mejor circunstanciales y parciales. Este artículo analiza el reciente entusiasmo generado por la idea de que los migrantes internacionales podrían regresar pronto a sus países de origen, iniciando unos flujos de migración en reversa, huyendo de sus malas condiciones de vida y de la ausencia de oportunidades en los países de acogida. Pese a este entusiasmo, la migración de retorno es un escenario hipotético. El retorno espontáneo masivo no se ha observado hasta ahora, a pesar de los incentivos que han

  2. Pressão arterial de 24 horas em mulheres idosas normotensas e com hipertensão do avental branco

    OpenAIRE

    Hekman, Paulo Rogério W.; Barbisan, Juarez N.; Menezes, Honório S.; Antonello, Vicente

    2010-01-01

    FUNDAMENTO: Mudanças no comportamento do ritmo circadiano podem ser deletérias, levando à lesão de órgãos-alvo, o que sugere ser de importante significado prognóstico e, eventualmente, podem também demandar intervenção terapêutica. OBJETIVO: Descrever e comparar os ritmos circadianos de pressão arterial (PA) entre mulheres idosas normotensas e portadoras de hipertensão do avental branco (HAB). MÉTODOS: Estudo transversal em uma amostra de 36 pacientes, com idades entre 60-83 anos, submetidas ...

  3. Propuesta de un servicio de emergencias sociales de atención 24 horas los 365 días en la ciudad de Valencia

    OpenAIRE

    Camús Jorques, Desirée; Cortés Cerdán, José Ignacio

    2017-01-01

    La emergencia social supone una situación que favorece procesos de vulnerabilidad social y de riesgo social, manifestando estados ocultos de precariedad y marginación. Las situaciones de emergencia social son sobrevenidas, afectan a necesidades básicas

  4. Measurement of ampere-hour for small consumers in Brazil: present status and trends; Medicao de ampere-hora para pequenos consumidores no Brasil: estado atual e perspectivas

    Energy Technology Data Exchange (ETDEWEB)

    Alves Junior, J.E.R.; Lippincott, M.; Caldas, R.P.; Costa, R.S. de; Alvarenga, L.M.; Loureiro, M.R.B.; Luiz, F.C. [Centro de Pesquisas de Energia Eletrica, Rio de Janeiro, RJ (Brazil). E-mail: alves@cepel.br; Santos, C.; Araujo, P. [Centrais Eletricas de Pernambuco (CELPE), Recife, PE (Brazil); Pinho, A. [Centrais Eletricas do Para (CELPA), Belem, PA (Brazil); Marcondes, P. [Daruma Telecomunicacoes e Informatica S.A., Sao Paulo, SP (Brazil); Vidal, J.C.M. [APEL Aplicacoes Eletronicas Industria e Comercio Ltda., Campina Grande, PB (Brazil); Peyro, R.J. [Telematica, Sao Paulo, SP (Brazil)

    1999-07-01

    This paper presents a description of the ampere-hour meter developed with the CEPEL technology. This meter aims to the economic optimization of the measurement and invoicing or the small scale consumer electric power consumption. The paper presents the description, the technical and construction characteristics, the invoicing system and the using by the electric power utilities.

  5. La hora de los operadores jurídicos. A propósito de las últimas reformas legales en materia laboral

    Directory of Open Access Journals (Sweden)

    Hugo Barreto Ghione

    2010-07-01

    Full Text Available Ya ha sido dicho y escrito casi todo acerca de la impronta fuertemente reformista que en lo laboral tuvo el período 2005 a 2009. Algunos lo han comparado con el proceso desatado por el primer batllismo desde 1915 y que se estiró hasta el comienzo de la crisis económica y social que se desplegó desde finales del decenio de los cincuenta. Barbagelata al estudiar la evolución deI derecho del trabajo periodiza este impulso reformista en dos etapas, que denomina de "fundación" y de "desarrollo" de la legislación laboral, señalando algunas permanencias y rasgos comunes del ciclo tales como la confianza en la ley, la ciudadanía laboral y la previsión y anticipación de los problemas sociales.

  6. La hora de los operadores jurídicos. A propósito de las últimas reformas legales en materia laboral

    OpenAIRE

    Hugo Barreto Ghione

    2010-01-01

    Ya ha sido dicho y escrito casi todo acerca de la impronta fuertemente reformista que en lo laboral tuvo el período 2005 a 2009. Algunos lo han comparado con el proceso desatado por el primer batllismo desde 1915 y que se estiró hasta el comienzo de la crisis económica y social que se desplegó desde finales del decenio de los cincuenta. Barbagelata al estudiar la evolución deI derecho del trabajo periodiza este impulso reformista en dos etapas, que denomina de "fundación" y de "desarrollo" de...

  7. Phonolite weathering profiles at Mariánská hora Hill, České středohoří Mts., and sorption properties of clay residues

    Czech Academy of Sciences Publication Activity Database

    Novák, Jiří Karel; Melka, Karel; Ulrych, Jaromír; Řanda, Zdeněk

    2005-01-01

    Roč. 2, 2 /138/ (2005), s. 135-149 ISSN 1211-1910. [Conference on Clay Mineralogy and Petrology /17./. Prague, 13.09.2004-17.09.2004] R&D Projects: GA AV ČR IAA3048201 Institutional research plan: CEZ:AV0Z3013912; CEZ:AV0Z1048901 Keywords : phonolite * weathering * saprolite Subject RIV: DB - Geology ; Mineralogy https://www.irsm.cas.cz/materialy/acta_content/2005_02/17_Novak.pdf

  8. A Hora da “Personalização em Massa”: do consumo de informações à algoritmização do cotidiano

    Directory of Open Access Journals (Sweden)

    LUCAS, Luciane

    2005-12-01

    Full Text Available The purpose of this paper is to study databases here considered a communication tool in a consumption perspective. As the object of analysis we chose the techniques which are applied to these databases and potentiate the information extracted from them – data mining tools are namely able to reveal tendencies, patterns and hidden nexuses between the data; therefore they are of increasing relevance to communicational decisions. Based on Peirce’s concepts of induction and abduction, this paper seeks to show, in the technological supports, the discursive practices which characterize contemporary society: forecast modeling (related to induction and knowledge discovery (mostly abductive. The point of focus of the paper is the attempt to demonstrate that technology has established itself as the main foundation of the predictive model in consumption society, thus allowing not only an algoritmization of daily life but also the consolidation of a strange communicational phenomenon: that of ‘mass personalization’.

  9. Frogs as a part of the Eneolithic diet. Archaeozoological records from the Czech Republic (Kutná Hora-Denemark site, Řivnáč Culture)

    Czech Academy of Sciences Publication Activity Database

    Kyselý, René

    2008-01-01

    Roč. 35, č. 1 (2008), s. 143-157 ISSN 0305-4403 Institutional research plan: CEZ:AV0Z80020508 Keywords : amphibians * common frog (Rana temporaria) * prehistoric food * anatomy representation * seasonality * chalcolithic * Central Europe Subject RIV: EG - Zoology Impact factor: 1.779, year: 2008 http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WH8-4NT57V1-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=393499f111a5c12f133425d45f4f6f01

  10. Política na hora do chá: ética e identidade no debate online sobre uma bebida

    Directory of Open Access Journals (Sweden)

    Luis Mauro Sá Martino

    2012-06-01

    Full Text Available Este trabalho analisa como um debate online sobre a mudança de sabor de chá da fábrica inglesa Twinings tornou-se parte de um discurso político sobre nação e identidade cultural. A alteração foi notícia em alguns dos principais diários britânicos, repercutiu nas redes sociais e ganhou cores políticas. Foram analisados 389 comentários às matérias publicadas no The Times, The Daily Telegraph e The Mail, além de uma página no Facebook, buscando compreender as principais linhas argumentativas a partir de critérios da ética do discurso de Habermas, em sua aplicação à discussão no ambiente online. A análise apontou três aspectos: (a o uso do chá para a politização de questões cotidianas que têm relevância moral e coletiva, implicando a reafirmação de uma identidade cultural britânica (b a crítica ao caráter “estrangeiro” da marca – a fábrica foi para a Polônia em 2010 por razões comerciais; (c a influência na decisão da empresa de retomar o antigo sabor.

  11. Coincidence of gabbro and granulite formation and their implication for Variscan HT metamorphism in the Moldanubian Zone (Bohemian Massif), example from the Kutná Hora Complex

    Czech Academy of Sciences Publication Activity Database

    Faryad, S. W.; Kachlík, V.; Sláma, Jiří; Jedlička, R.

    2016-01-01

    Roč. 264, 1 October (2016), s. 56-69 ISSN 0024-4937 Institutional support: RVO:67985831 Keywords : spinel-bearing gabbro * Variscan age * granulite * heat source Subject RIV: DB - Geology ; Mineralogy Impact factor: 3.677, year: 2016

  12. Student Perception on Group Work and Group Assignments in Classroom Teaching: The Case of Bule Hora University Second Year Biology Students, South Ethiopia--An Action Research

    Science.gov (United States)

    Daba, Tolessa Muleta; Ejersa, Sorale Jilo; Aliyi, Sultan

    2017-01-01

    Group learning has become a common practice in schools and tertiary institutions. It provides more comfortable and supportive learning environment than solitary work. It fosters critical thinking skills, develops individual accountability, increases levels of reasoning and positive interdependence, improves problem-solving strategies and…

  13. Deterioro cognitivo y horas de sueño en mayores de 65 años no institucionalizados: estudio en farmacia comunitaria

    OpenAIRE

    Climent, Mª Teresa; Ballesteros, Cristina; Colomer, Vicente; Botella, Paloma; Moreno, Lucrecia

    2015-01-01

    Objetivo: Determinar factores de riesgo, relacionados con el estilo de vida, asociados con la presencia de deterioro cognitivo en personas mayores de 65 años. Método: Para ello se diseñó un estudio observacional transversal con personas mayores de 65 años no institucionalizadas mediante entrevista personal estructurada. El estudio se realizó en 14 farmacias de la Comunidad Valenciana desde marzo 2011 hasta marzo de 2013. Se utilizan como test de cribado el Short Portable Mental State Ques...

  14. Organización e instrumentación de la gestión a la hora de los cambios socio-productivos

    Directory of Open Access Journals (Sweden)

    Michel Capron

    2001-06-01

    Full Text Available Con este artículo se pretende ilustrar al lector, sobre la forma en que los cambios sociales y/o productivos afectan la gestión, y a la vez, como ésta puede actuar para minimizar los impactos negativos sobre la organización. Por ello, la primera parte es una contextualización de los principales factores que han afectado notoriamente la vida empresarial durante las últimas dos décadas, en una segunda sección se analiza la forma de evaluar y de medir tanto las acciones como los resultados en el nuevo contexto organizacional; por último, se Invita a la reflexión sobre los nuevos criterios y los nuevos dispositivos de evaluación

  15. Mistura de biodiesel de sebo bovino em motor diesel durante 600 horas Blend of biodiesel from beef tallow in a diesel engine during 600 hours of tests

    Directory of Open Access Journals (Sweden)

    Ila Maria Corrêa

    2011-07-01

    Full Text Available O biodiesel de sebo bovino é considerado uma alternativa de baixo custo e de grande disponibilidade por ser resíduo da produção agropecuária brasileira, que é uma das maiores do mundo. Raros são os trabalhos que mostram a utilização do biodiesel de sebo bovino em motores diesel. Assim, o objetivo deste trabalho foi verificar o efeito da mistura de biodiesel bovino na proporção de 5% ao óleo diesel comercial no desempenho do motor, possíveis consequências internas no motor e nas características do óleo lubrificante após o uso prolongado em motor diesel. Foram realizados ensaios em bancada dinamométrica utilizando um trator agrícola. O desempenho do motor foi determinado através da tomada de potência (TDP. O motor foi operado por 600h durante as quais foi determinada a potência, o consumo de combustível e analisadas as amostras de óleo lubrificante a cada 100h. Ao final do ensaio, o motor foi aberto e inspecionado. A análise do óleo lubrificante mostrou nível de contaminação crítico a partir das 400h, mas a inspeção visual do motor não detectou nenhum desgaste interno. O motor funcionou normalmente, embora tenha ocorrido tendência de redução na potência e aumento de consumo de combustível ao longo das 600h.Biodiesel from beef tallow has been considered a low-cost and high availability alternative due to be residue from the Brazilian livestock production, one of the world's largest. Papers that show the use of biodiesel from beef tallow in diesel engine are rare. The aim of this study was to investigate the effect of blend of biodiesel from beef tallow (B5 in commercial diesel oil on engine performance, analyzing possible internal consequences and characteristics of lubricating oil after the prolonged use in a diesel engine. Engine performance was evaluated through tractor power take off (PTO tests. The engine was operated for 600 hours. Power and fuel consumption were measured. Samples of lubricating oil were analyzed by the end of each 100 partial hours. At the end of the test the engine was opened and visually inspected. Analysis of engine lubricating oil has showed critical level of contamination after 400 hours but the visual inspection of engine did not detect any internal wear. The engine performance was satisfactory although there was tendency of reduction in power and increase on fuel consumption along the 600 hours.

  16. Desvinculación de la asistencia ventilatoria mecánica prolongada a las 72 horas de respiración espontánea

    Directory of Open Access Journals (Sweden)

    Darío Villalba

    2015-02-01

    Full Text Available El objetivo del presente trabajo fue describir la población que ingresó en un centro de desvinculación de la ventilación mecánica y rehabilitación (CDVMR en asistencia ventilatoria mecánica invasiva (AVMi, analizar su evolución y determinar los predictores de fracaso de la desvinculación de la AVMi. Se revisaron las historias clínicas de 763 pacientes que ingresaron en el servicio de Cuidados Respiratorios, en el período comprendido entre mayo 2005 y enero 2012, se seleccionaron 372 con traqueotomía y AVMi. Se analizaron diferentes variables como posibles predictores de desvinculación. La media de edad fue 69 años (DS 14.7, 57% fueron hombres. La mediana de días de internación en la unidad de terapia intensiva (UTI fue de 33 (rango intercuartilo-RQ 26-46. El 86% de los ingresados a UTI fue por causa médica. Durante la internación en el CDVMR lograron desvincularse el 50%; mediana de días de desvinculación, 13 (RQ 5-38. La edad fue predictor de fracaso de desvinculación. Al estudiar a la subpoblación con desvinculación parcial, se sumó el antecedente de EPOC como predictor. Si bien un 25% de los pacientes falleció o requirió derivación a un centro de mayor complejidad antes de 2 semanas de internación, más de la mitad de los pacientes lograron ser desvinculados definitivamente de la AVMi; esto podría sustentar la atención de pacientes críticos crónicos en CDVMR en la Argentina, ya que los pacientes internados en estos centros tienen buena expectativa de desvinculación, a pesar de las altas chances de desarrollar complicaciones.

  17. Meteorological Reference Years of Daily Mean Temperature during the Sunlight Time; Anos Tipos de Temperaturas Medias Diarias durante las Horas de Sol

    Energy Technology Data Exchange (ETDEWEB)

    Marchante Jimenez, M.; Ramirez Santigosa, L.N.; Mora Lopez, L.; Sidrach de Cardona Ortin, M.

    2002-07-01

    In this work the characterization of the daily mean temperature during the sunlight time has been analyzed. An algorithm for the hourly series generation from extreme daily values has been applied to evaluate the daily mean temperature during the sunlight time. A generic algorithm has been enounced as a function of the sunrise time. This algorithm allows taking into account the fractions related to the sunrise and sunset hours. This methodology has been applied in data from 45 Spanish stations, uniformly distributed in the Iberian Peninsula. Data for a period of 14 years has been used in most of locations, and once the interest variable has been calculated, the meteorological reference year of the daily mean temperature during the sunlight time has been evaluated in each stations. The next step is the evaluation of the daily mean temperature during the sunlight time in any point into the zone of evaluation, not only in the measured stations. >From the result data in each measured station, an geographic information system has been used in order to calculate the interpolation, obtaining maps with a data each 5 km for each of the 365 days of the year. Then, this results can be superposed with the solar radiation evaluation obtaining the input data for the sizing of the photovoltaic grid connected system in any point of the Spanish geography. (Author) 8 refs.

  18. Enfoque en las horas despues del dia en escuela para la prevencion de violencia (Focus on After-School Time for Violence Prevention). ERIC Digest.

    Science.gov (United States)

    Patten, Peggy; Robertson, Anne S.

    Perhaps 8 million children spend the after-school hours at home alone. In the absence of adult supervision, many of these youth are likely to engage in delinquent or other high-risk activities. This Spanish-language digest reveals research that suggests after-school programs can help to prevent youths from engaging in these activities in two ways:…

  19. Beer-spoiling Ability of Lactic Acid Bacteria and its Relation with Genes horA, horC a hitA

    Czech Academy of Sciences Publication Activity Database

    Matoulková, D.; Kubizniaková, P.; Sigler, Karel

    2012-01-01

    Roč. 58, 11-12 (2012), s. 336-342 ISSN 0023-5830 R&D Projects: GA MŠk 1M0570 Institutional support: RVO:61388971 Keywords : beer spoilage * lactic acid bacteria Subject RIV: EE - Microbiology, Virology

  20. Utilidad de la onda P300 como marcador de fatiga cognitiva en médicos internos residentes tras una jornada laboral de 24 horas

    OpenAIRE

    Estarelles Marco, María Jesús

    2015-01-01

    La onda P300 fue el primer potencial evocado cognitivo que se conoció, descrita en 1965 por Sutton et al. Se caracteriza por una gran onda positiva, máxima en línea media del cuero cabelludo, que aparece alrededor de 300 milisegundos después de un estímulo infrecuente y relevante para una tarea. Viene determinada por la latencia al pico máximo y por su amplitud, parámetros que pueden afectarse por la privación de sueño, como se ha visto en estudios previos. La afectación de las habilidade...

  1. ESMA, hora cero : Las noticias sobre la Escuela de Mecánica de la Armada en la prensa de la transición

    Directory of Open Access Journals (Sweden)

    Claudia Feld

    2008-11-01

    Full Text Available La ESMA (Escuela de Mecánica de la Armada fue uno de los centros clandestinos de tortura y desaparición más activos de la última dictadura militar argentina (1976-1983: se estima que unos 5.000 desaparecidos fueron detenidos allí. A partir de la década de 1990, la ESMA se transformó en un lugar "emblemático" del recuerdo y su imagen suele ser presentada como condensación de todas las atrocidades del terrorismo de Estado. Este trabajo se propone interrogar esta centralidad de la ESMA y reconstruir el proceso de su "emblematización". El artículo analiza las representaciones de la ESMA en la prensa argentina durante los primeros meses de la apertura democrática (entre enero y mayo de 1984. Estas representaciones, conocidas como "show del horror" por su lenguaje macabro y sensacionalista, ofrecen pistas claras para emprender una reflexión sobre el primer proceso de calificación operado sobre ese lugar antes del advenimiento de los principales relatos "fundadores" de la transición democrática: el informe de la comisión de la CONADEP y el juicio a los ex comandantes.

  2. Analysis of rainfall preceding debris flows on the Smědavská hora Mt., Jizerské hory Mts., Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Smolíková, J.; Blahůt, Jan; Vilímek, V.

    2016-01-01

    Roč. 13, č. 4 (2016), s. 683-696 ISSN 1612-510X Institutional support: RVO:67985891 Keywords : debris flow * rainfall pattern * rainfall thresholds * Jizerské hory Mts. * Czech Republic Subject RIV: DE - Earth Magnetism, Geodesy, Geography Impact factor: 3.657, year: 2016

  3. Hora est 7. Is positiviteit het geheime ingrediënt? Cariës, overgewicht en probleemgedrag bij kinderen: de rol van ouders en het gezin

    NARCIS (Netherlands)

    de Jong-Lenters, M.

    2016-01-01

    In this doctoral research project the relationship between, on the one hand, parenting and the functioning of families, and, on the other, child dental health were measured on the basis of interviews, questionnaires and observations of parent-child interaction. The groups studied consisted of

  4. ¿Ha llegado la hora de la gestión de las listas de espera? Has the time arrived for the management of waiting lists?

    Directory of Open Access Journals (Sweden)

    E. Bernal

    2002-10-01

    Full Text Available Las personas que ocupan una lista de espera sufren a menudo un riesgo adicional derivado del tiempo que pasa hasta que obtienen tratamiento; sin embargo, en otras ocasiones, las personas en lista no tienen necesidad del tratamiento por el que esperan. Ambos argumentos, contrastables con evidencias empíricas, serían suficientes para afirmar que debe llegar la gestión a las listas de espera dejando a un lado políticas más o menos oportunistas. Por políticas oportunistas se entiende mantener la mala información sobre listas o su "maquillaje", utilizar programas de autoconcertación sin más horizonte que llegar a final de año sin lista de más de seis meses, etcétera. El panorama no es del todo oscuro. Algunas iniciativas de gestión (incluso de Política con mayúscula se van abriendo paso y pueden entrar en la agenda de los próximos años. Así, cabe destacar la aplicación de tiempos de atención garantizada o la priorización de las listas en función de criterios explícitos. En todo caso, conviene recordar que, con la excepción de las colas producidas en las salas de espera de los centros de salud y aquéllas que se producen en las puertas de urgencias, el resto de colas del sistema están mediadas por la decisión de un médico. Así que una estrategia ineludible para gestionar las listas de espera consiste en atenuar los problemas derivados de la incertidumbre (o ignorancia con respecto al diagnóstico o al pronóstico de los pacientes.Individuals on the waiting list frequently suffer an additional risk caused by the mean time until they receive treatment; however, other individuals do not need the treatment for which they are waiting. Both arguments, which can be contrasted with empirical evidence, would be sufficient to affirm that waiting list management should be implemented, leaving aside policies that are more of less opportunistic. Opportunistic policies are understood as those providing misinformation on waiting lists or their "manipulation", and using programs of auto-coordination with the sole aim of reaching the end of the year without a waiting list of not more than six months, etc. The panorama is not completely bleak. Some management initiatives (and even Politics with a capital P are opening the way forward and may enter the Agenda in the next few years. In this context, the application of guaranteed times of medical care or the prioritization of waiting lists according to explicit criteria should be highlighted. It is worth remembering that, except for the queues in the waiting rooms of health centers and emergency departments, waiting lists are mediated by the decision of the physician. Therefore, an essential strategy for managing waiting lists consists of attenuating the problems caused by uncertainty (or ignorance of the patient's diagnosis or prognosis.

  5. Pressão arterial de 24 horas em mulheres idosas normotensas e com hipertensão do avental branco Presión arterial de 24 horas en mujeres mayores normotensas y con hipertensión de la bata blanca 24-hour blood pressure in normotensive elderly women and elderly women with white-coat hypertension

    OpenAIRE

    Paulo Rogério W. Hekman; Juarez N. Barbisan; Honório S. Menezes; Vicente Antonello

    2010-01-01

    FUNDAMENTO: Mudanças no comportamento do ritmo circadiano podem ser deletérias, levando à lesão de órgãos-alvo, o que sugere ser de importante significado prognóstico e, eventualmente, podem também demandar intervenção terapêutica. OBJETIVO: Descrever e comparar os ritmos circadianos de pressão arterial (PA) entre mulheres idosas normotensas e portadoras de hipertensão do avental branco (HAB). MÉTODOS: Estudo transversal em uma amostra de 36 pacientes, com idades entre 60-83 anos, submetidas ...

  6. Anestesia regional e trombocitopenia não pré-eclâmptica; hora de repensar o nível seguro de plaquetas Anestesia regional y trombocitopenia no preclámptica; es hora de pensar de nuevo sobre el nivel seguro de plaquetas Regional anesthesia and non-preeclamptic thrombocytopenia: time to re-think the safe platelet count

    Directory of Open Access Journals (Sweden)

    Motoshi Tanaka

    2009-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Apesar de a anestesia regional ser amplamente utilizada no controle da dor em obstetrícia, seu uso pode não ser apropriado nas pacientes com trombocitopenia por causa do risco de hematoma no neuroeixo. Não existem fortes evidências sugerindo número mínimo de plaquetas necessário para garantir a segurança na realização da anestesia regional. O objetivo deste estudo foi rever a segurança da anestesia regional em pacientes com trombocitopenia não pré-eclâmptica na instituição durante período de cinco anos. MÉTODO: Foi realizada revisão retrospectiva dos prontuários médicos de todas as pacientes obstétricas não pré-eclâmpticas cujo parto foi realizado na instituição entre abril de 2001 e março de 2006 e que apresentaram contagem de plaquetas JUSTIFICATIVA Y OBJETIVOS: A pesar de que la anestesia regional esté siendo muy utilizada en el control del dolor en obstetricia, su uso puede no ser muy apropiado en las pacientes con trombocitopenia, debido al riesgo de hematoma en el neuro eje. No existen fuertes evidencias que sugieran un número mínimo de plaquetas necesario para garantizar la seguridad en la realización de la anestesia regional. El objetivo de este estudio fue analizar la seguridad de la anestesia regional en pacientes con trombocitopenia no preeclámptica en la institución durante un período de cinco años. MÉTODO: Fue realizada revisión retrospectiva de las historias clínicas médicas de todas las pacientes obstétricas no preeclámpticas cuyo parto fue realizado en la institución entre abril de 2001 y marzo de 2006 y que presentaron BACKGROUND AND OBJECTIVES: Although regional anesthesia is widely used for pain control in obstetrics, it may not be appropriate for patients with thrombocytopenia due to the risk of neuraxial hematoma. There is no strong evidence to suggest the minimum platelet count that is necessary to ensure the safe practice of regional anesthesia. The purpose of this study was to review the safety of regional anesthesia in non-preeclamptic thrombocytopenic parturients at our institution over a 5-year period. METHODS: A retrospective chart review was performed in all the non-preeclamptic obstetric patients who delivered at our facility between April 2001 and March 2006, and had platelet counts < 100 × 10(9.L-1 on the day of anesthesia. The etiology of the thrombocytopenia, type of anesthesia, mode of delivery and major anesthetic complications were noted. RESULTS: Seventy-five patients were identified, 47 of whom (62.6% had received regional anesthesia. The etiology of their thrombocytopenia was immune thrombocytopenic purpura in 49 patients, gestational thrombocytopenia in 20 and other causes in 6 patients. Regional anesthesia was administered in 91.9% of the patients with platelet counts of 80 to 99 × 10(9.L-1 and in 48.1% of the patients with platelet counts of 50 to 79 × 10(9.L-1. None of the 11 patients with platelet counts below 50 × 10(9.L-1 received regional anesthesia. There were no neurological complications. CONCLUSIONS: In our series, regional anesthesia was safely administered in pregnant patients with platelet counts between 50-79 × 10(9.L-1. Our results are in keeping with other series in the literature. We suggest that in non-preeclamptic patients with stable platelet counts and no history or clinical signs of bleeding, the lower limit of platelet count for regional anesthesia should be 50 × 10(9.L-1

  7. La lectura por placer: su incidencia en el rendimiento académico, las horas de televisión y las horas de videojuegos. The pleasure of reading: its impact on academic achievement, on TV-watching hours and video games-playing hours

    OpenAIRE

    Teresa Dezcallar; Mercè Clariana; Ramón Cladellas; Mar Badia; Concepció Gotzens

    2014-01-01

    En el presente trabajo se ha relacionado el gusto y la afición por la lectura y el tiempo que pasan los alumnos viendo la televisión o jugando a videojuegos en los ratos de ocio, y cómo estas variables correlacionan con el rendimiento académico, medido a través de las notas escolares. La muestra ha sido compuesta por un total de 510 alumnos de los tres ciclos de educación primaria de escuelas públicas y privadas españolas. Los datos se obtuvieron mediante cuestionarios dirigidos a los padres....

  8. Formation of lysinoalanine in egg white under alkali treatment.

    Science.gov (United States)

    Zhao, Yan; Luo, Xuying; Li, Jianke; Xu, Mingsheng; Tu, Yonggang

    2016-03-01

    To investigate the formation mechanism of lysinoalanine (LAL) in eggs during the alkali treatment process, NaOH was used for the direct alkali treatment of egg white, ovalbumin, and amino acids; in addition, the amount of LAL formed during the alkali treatment process was measured. The results showed that the alkali treatment resulted in the formation of LAL in the egg white. The LAL content increased with increasing pH and temperature, with the LAL content first increasing and then leveling off with increasing time. The amount of LAL formed in the ovalbumin under the alkali treatment condition accounted for approximately 50.51% to 58.68% of the amount of LAL formed in the egg white. Thus, the LAL formed in the ovalbumin was the main source for the LAL in the egg white during the alkali treatment process. Under the alkali treatment condition, free L-serine, L-cysteine, and L-cystine reacted with L-lysine to form LAL; therefore, they are the precursor amino acids of LAL formed in eggs during the alkali treatment process. © 2016 Poultry Science Association Inc.

  9. Enhanced computational methods for quantifying the effect of geographic and environmental isolation on genetic differentiation

    DEFF Research Database (Denmark)

    Botta, Filippo; Eriksen, Casper; Fontaine, Michaël C.

    2015-01-01

    1. In a recent paper, Bradburd et al. (Evolution, 67, 2013, 3258) proposed a model to quantify the relative effect of geographic and environmental distance on genetic differentiation. Here, we enhance this method in several ways. 2. We modify the covariance model so as to fit better with mainstre...... available as an R package called sunder. It takes as input georeferenced allele counts at the individual or population level for co-dominant markers. Program homepage: http://www2.imm.dtu.dk/~gigu/Sunder/....

  10. Effect of basic alkali-pickling conditions on the production of lysinoalanine in preserved eggs.

    Science.gov (United States)

    Zhao, Yan; Luo, Xuying; Li, Jianke; Xu, Mingsheng; Tu, Yonggang

    2015-09-01

    During the pickling process, strong alkali causes significant lysinoalanine (LAL) formation in preserved eggs, which may reduce the nutritional value of the proteins and result in a potential hazard to human health. In this study, the impacts of the alkali treatment conditions on the production of LAL in preserved eggs were investigated. Preserved eggs were prepared using different times and temperatures, and alkali-pickling solutions with different types and concentrations of alkali and metal salts, and the corresponding LAL contents were measured. The results showed the following: during the pickling period of the preserved egg, the content of LAL in the egg white first rapidly increased and then slowly increased; the content of LAL in the egg yolk continued to increase significantly. During the aging period, the levels of LAL in both egg white and egg yolk slowly increased. The amounts of LAL in the preserved eggs were not significantly different at temperatures between 20 and 25ºC. At higher pickling temperatures, the LAL content in the preserved eggs increased. With the increase of alkali concentration in the alkali-pickling solution, the LAL content in the egg white and egg yolk showed an overall trend of an initial increase followed by a slight decrease. The content of LAL produced in preserved eggs treated with KOH was lower than in those treated with NaOH. NaCl and KCl produced no significant effects on the production of LAL in the preserved eggs. With increasing amounts of heavy metal salts, the LAL content in the preserved eggs first decreased and then increased. The LAL content generated in the CuSO4 group was lower than that in either the ZnSO4 or PbO groups. © 2015 Poultry Science Association Inc.

  11. Diseño de una central solar termoeléctrica de 50 Mw con 4 horas de almacenamiento con tecnología de canales parabólicos

    OpenAIRE

    Crespo Mencía, Diego

    2010-01-01

    En este proyecto, se detallan la metodología para el diseño de plantas termosolares y se calculan los principales parámetros para el diseño de la misma. El diseño tiene dos partes fundamentales. Por una parte la captación de la energía solar mediante un diseño optimizado del campo solar y por otra parte el diseño de ciclo de conversión de potencia con todos sus componentes auxiliares. La planta escogida tiene una potencia instalada de 50 MWe netos, que es el límite superior de potencia par...

  12. Detección de lesión de órgano diana y rigidez arterial mediante monitorización de la presión arterial en 24 horas y frecuencia cardiaca en pacientes hipertensos

    OpenAIRE

    García García, Ángel

    2013-01-01

    [ES] Las enfermedades cardiovasculares son la primera causa de morbi-mortalidad en los países desarrollados y la hipertensión arterial es el principal factor de riesgo para su aparición. Es responsable del 54% de los ictus y del 47% de las cardiopatías isquémicas y, un retraso en su diagnóstico y tratamiento, conlleva a la aparición de lesiones de órganos diana. La lesión de órgano diana renal se evalúa con la creatinina plasmática, la tasa de filtrado glomerular o la microalbuminuria;...

  13. Gestão, planejamento e avaliação de políticas de ciência e tecnologia: hora de rever? Management, planning and assessment of science and technology policies: time to review?

    Directory of Open Access Journals (Sweden)

    Marília Bernardes Marques

    1999-01-01

    Full Text Available O presente artigo aborda o tema das políticas de ciência e tecnologia e as questões relativas à sua gestão, planejamento e avaliação. Revisa a trajetória da ciência e tecnologia nas cinco últimas décadas deste século, analisando como a ciência voltou-se progressivamente para os mercados e empresas de alta tecnologia, ao mesmo tempo em que cresceria a intervenção do Estado dirigida à integração da ciência e da tecnologia ao conjunto da economia. A seguir, analisa a noção de sistema nacional de inovação e suas relações com o tema das políticas de ciência e tecnologia. O texto finaliza retomando o problema dos limites e dos rumos da ação governamental sobre a ciência e a tecnologia nos países em desenvolvimento e subdesenvolvidos.This article addresses the issue of science and technology policies as well as its management and evaluation. Reviews the trajectory of science and technology during the last five decades of this century and analyses how science has progressively turned to the markets and to high-tech firms, simultaneously to the increase in the governmental intervention steered to integrate science and technology in the whole economy. It also analyses the notion of national innovation system and its relations with the science and technology policies. To conclude, the paper considers the problem of the limits and trends of the governmental action directed to science and technology in developing and underdeveloped countries.

  14. O atendimento às vítimas de violência na emergência: "prevenção numa hora dessas?" Medical care for victims of violence in emergency room: is it time for prevention?

    Directory of Open Access Journals (Sweden)

    Suely F. Deslandes

    1999-01-01

    Full Text Available Neste artigo discutem-se as possibilidades de prevenção que o setor de emergência pode desencadear diante dos casos de violências. Apóia-se nos dados de pesquisa em que se analisaram os atendimentos feitos às vítimas de "causas externas" em dois hospitais públicos de emergência no Rio de Janeiro. Optou-se, neste trabalho, por tratar de forma breve as principais "causas externas" atendidas (entre acidentes e violências, enfatizando-se os atendimentos de violência doméstica contra crianças, contra mulheres e os de tentativas de suicídios. A metodologia da pesquisa articulou o estudo descritivo de base quantitativa a uma abordagem qualitativa construída através de observação de campo e de entrevistas. A partir dos dados empíricos, trava-se uma discussão sobre o atendimento realizado e as oportunidades de prevenção possíveis e as condições necessárias para esta tarefa.This paper discusses violence prevention possibilities that could be raised in emergency. It draws on the research data that analysed medical care for the victims of "external causes" in two public emergency hospitals in Rio de Janeiro. This work deals briefly with the main "external causes" (among accidents and violence which were treated there and emphasizes the care given to the victims of child abuse, battered women and attempts of suicides. The research methodology articulates the descriptive study of quantitative base to a qualitative approach developed through field observation and interviews. Starting from the empiric data, it discusses the medical care received by the victims and the possible prevention opportunities and the necessary conditions for this task.

  15. Comparação entre as características do sêmen humano preservado a +4ºC e -196ºC por 24 horas

    Directory of Open Access Journals (Sweden)

    Mattos Ana Luiza Gelpi

    2003-01-01

    Full Text Available OBJETIVOS: avaliar as características do sêmen humano preservado a +4ºC e a -196ºC por 24 h e determinar a técnica ideal para utilização em procedimentos específicos. MÉTODOS: amostras de sêmen de 24 voluntários foram analisadas após a coleta e divididas em duas alíquotas, uma resfriada em a +4ºC e outra congelada a -196ºC. As amostras foram mantidas em baixas temperaturas por 24 h e então em temperatura ambiente por 30 minutos (T1, capacitadas (T2 e incubadas a +37ºC por 90 minutos (T3, sendo avaliadas quanto à concentração e motilidade progressiva em T1, T2 e T3. Para análise dos resultados obtidos com as duas diferentes técnicas foi utilizado o Modelo Linear Geral e para análise dos dados obtidos com a mesma técnica, em dois diferentes momentos de observação, foi utilizado o teste de Wilcoxon (a de 5% e p0,05 quanto à concentração, motilidade e NTEM entre as técnicas nos três momentos de observação. Tampouco houve diferença entre as variáveis após capacitação e após incubação no sêmen resfriado, mas, no congelado, a concentração foi significativamente superior após capacitação. CONCLUSÕES: embora a concentração e a motilidade progressiva não tenham diferido em ambas as técnicas, sugere-se o uso do resfriamento em procedimentos específicos a curto prazo, devido à simplicidade e baixo custo. Quando o sêmen congelado for necessário, recomenda-se a utilização logo após a capacitação para evitar redução da qualidade do mesmo.

  16. Mineral and textural evolution of a subvolcanic A-type granite: Hora Svaté Kateřiny stock, Krušné Hory Mts., Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Breiter, Karel

    2008-01-01

    Roč. 36, č. 6 (2008), s. 365-382 ISSN 0303-4534 R&D Projects: GA AV ČR IAA300130801 Institutional research plan: CEZ:AV0Z30130516 Keywords : A-type granite * rock textures * mineralogy * geochemistry * Krušné Hory Mts. * Erzgebirge Subject RIV: DB - Geology ; Mineralogy http://www.zgw-online.de/pages/_ausgabe2008.php

  17. “Dios nos mejore las horas si nos conviene”: La salud y la enfermedad de una familia montañesa del siglo XIX a través del estudio de las escrituras del yo

    Directory of Open Access Journals (Sweden)

    Rubalcaba Pérez, Carmen

    2011-12-01

    Full Text Available From birth in the seventies of the twentieth century of the so-called Anthropology of Health and Disease, the recognition of health and disease as cultural phenomena was introduced and anthropologists began to deepen in understanding how to develop the concepts of healthy and sick. The social history of literacy through the study of written records of the past, constitutes an irreplaceable resource for analyzing the social and cultural dimensions of disease process in its historical dimension. Through the analysis of private handwritten documents —personal correspondence and records in accounting books— of a small wealthy landowner, Pedro Jado Agüero (1815-1891, we know how the disease is not just a biological dysfunction, but also an array of culturally established meanings that we must try to unravel. Discovering the symbolism of the disease through the analysis of all the experiences, words and feelings used or described by members of a culture means to move further to the knowledge of the structure of meanings of the same culture.

    A partir del nacimiento, en los años setenta del siglo XX, de la denominada antropología de la salud y la enfermedad, se inició el reconocimiento de ambos estados como fenómenos culturales y los antropólogos comenzaron a sumergirse en la comprensión de la manera en que se elaboran los conceptos de sano y enfermo. La historia social de la cultura escrita, a través del estudio de los testimonios escritos del pasado, se constituye en un recurso insustituible para analizar las dimensiones sociales y culturales del proceso de enfermar en su dimensión histórica. A través del análisis de la documentación autógrafa de carácter privado —correspondencia y anotaciones personales en libros de cuentas— de un pequeño propietario rural acomodado, Pedro Jado Agüero (1815- 1891, se muestra cómo la enfermedad no consiste sólo en una disfunción biológica, sino también en una matriz de significados culturalmente establecidos que hay que intentar desentrañar. Descubrir el sentido simbólico de la enfermedad a través del análisis del conjunto de experiencias, de palabras y de sentimientos utilizados o descritos por los integrantes de una cultura significa acercarse en mayor medida al conocimiento de su estructura de significados.

  18. La hora de la TV: incursión de la televisión y la telenovela en la vida cotidiana de la ciudad de México (1958-1966)

    OpenAIRE

    Ramírez Bonilla, Laura Camila

    2015-01-01

    Resumen La televisión y los géneros televisivos son dispositivos con historia propia. En el caso mexicano, la telenovela se puede considerar como el primer género auténticamente concebido y realizado para la televisión. Su llegada al país, en junio de 1958, en Telesistema-Canal 4, no solo recogió parte de los estereotipos, los mitos y las preocupaciones morales de la sociedad de la época, sino que se insertó en la cotidianidad de los espectadores, aún neófitos y expectantes ante el producto. ...

  19. CARACTERÍSTICAS IN VITRO E FERTILIDADE DO SÊMEN CAPRINO ARMAZENADO A 5°C POR 24 HORAS UTILIZANDO DUAS CONCENTRAÇÕES DE GEMA DE OVO NO DILUENTE

    Directory of Open Access Journals (Sweden)

    Charles André Souza Bispo

    2011-12-01

    Full Text Available The objective of this study was to evaluate by in vitro tests and in vivo fertility, two concentrations of egg yolk (T1 = 20% or T2 = 2.5% in egg yolk-citrate semen extender for storing goat semen at 5°C for 24 hours. Ninety semen collections were performed in four goats. The semen was split and diluted in two different semen extenders and stored in refrigerator at 5°C for 24 hours, until the semen evaluation and insemination procedures. The average values for cooled semen, respectively, for T1 and T2 were motility, 68.5 ± 15.4 and 78.0 ± 5.5 (p < 0.05; vigor, 2.5 ± 0.6 and 3.2 ± 0.3 (p < 0.05, supravital test, 59.4 ± 17.2 and 71.1 ± 10.5 (p < 0.05 and hypoosmotic test, 42.2 ± 15.7 and 56.2 ± 11.5 (p < 0.05. The fertility rate was greater (p < 0.05 in T1 (31.3% than in T2 (66.7% and the prolificacy did not differ (p < 0.05 between T1 (1.3 ± 0.5 and T2 (1.4 ± 0.5. In conclusion, the egg yolk-citrate extender with a low concentration (2.5% of egg yolk was more effective in preserving the viability and fertility of goat semen stored at 5°C for 24 hours.

  20. Scientific values of landforms as the basis for the declaration of protected sites (a case study of Mt. Kraví hora in the Novohradské hory Mts., Czech Republic)

    Czech Academy of Sciences Publication Activity Database

    Rypl, J.; Kirchner, Karel

    2017-01-01

    Roč. 15, č. 3 (2017), s. 1537-1550 ISSN 1589-1623 Institutional support: RVO:68145535 Keywords : geomorphological inventory * geomorphologically significant sites * geoeducation * geotourism * geoconservation Subject RIV: DE - Earth Magnetism, Geodesy, Geography OBOR OECD: Physical geography Impact factor: 0.681, year: 2016 http://www.aloki.hu/pdf/1503_15371550.pdf

  1. Kilómetro por hora, ji cuadrado, días-hormiga: temas dimensionales, métricos y algebraicos en las tareas de redacción, edición y traducción

    OpenAIRE

    José A. Tapia Granados

    2004-01-01

    Este trabajo comenta algunos aspectos básicos de teoría métrica, análisis dimensional y álgebra relativos a las magnitudes y cantidades de uso habitual en la vida cotidiana y en todos los campos de las ciencias naturales y sociales. Se trata de aspectos muy generales, cuyo conocimiento parece necesario para todos los implicados en la redacción de textos en castellano. El artículo presta especial atención a algunos problemas que surgen al traducir del inglés, explica las ambigüedades matemátic...

  2. EFEITO DOS MEIOS DILUÍDORES MMC (MÍNIMA CONTAMINAÇÃO E LGM (LACTOSE-GEMA MODIFICADO NA VIABILIDADE DO SÊMEN DE CÃES CONSERVADO POR 24 HORAS EM EQUITAINER®.

    Directory of Open Access Journals (Sweden)

    Tania Goes de Pinho

    2011-03-01

    Full Text Available The aim of this study was to compare the viability of canine semen after dilution in Minimum Contamination Medium (MMC and Modified Lactose-Egg yolk extender (LGM and incubation at 4 ºC for 12 and 24 hours. Thirteen ejaculates were collected from 5 adult dogs by digital manipulation. Macroscopic and microscopic characteristics were assessed right after collection. Semen was divided to be diluted (1:3 in MMC and LGM and subsequently chilled in Equitainer®. Seminal parameters of motility and spermatic morphology, membrane integrity (hyposmotic test, spermatic viability and spontaneous acrosome reaction (Trypan-blue Giemsa stain were evaluated in fresh and chilled semen after 12 and 24 hours of incubation at 4 ºC. No difference between extenders was identified in semen conservation after 12 hours. After 24 hours just spermatic motility was different (p>0.05. But, after both periods of conservation, semen diluted in LGM maintained most of the characteristics verified in the fresh semen. The mean of true and false acrosome reaction did not exceed 2% in both semen extenders, which demonstrates no influence of media component and incubation period on these phenomena at 4 ºC. In conclusion, these results indicate that both extenders can be used in canine semen conservation at 4 ºC in contêiner during 12 hours without significant changes in semen characteristics.

  3. Scopeloides glarisianus (Gonostomatidae, Stomiiformes) na středně oligocenní lokalitě Rožnov pod Radhoštěm – Rysova hora

    Czech Academy of Sciences Publication Activity Database

    Přikryl, Tomáš

    2008-01-01

    Roč. 2007, - (2008), s. 130-131 ISSN 0514-8057 Institutional research plan: CEZ:AV0Z30130516 Keywords : fish * biostratigraphy * Western Carpathians * Paleogene Subject RIV: DB - Geology ; Mineralogy http://www.geology.cz/zpravy/obsah/2007/2007-36.pdf

  4. The Execution of the Miners of Kutná Hora at Poděbrady and in Křivoklát in 1496. On the Veneration of the Miners of Poděbrady in the Sixteenth Century

    Czech Academy of Sciences Publication Activity Database

    Šárovcová, Martina

    Suppl., č. 2 (2015), s. 259-278 ISSN 0015-1831 Institutional support: RVO:68378033 Keywords : music manuscripts * Utraquism * Bohemian Reformation * illuminated fragments * Jan Hus * Fabián Puléř * early modern illuminated manuscripts Subject RIV: AL - Art, Architecture, Cultural Heritage

  5. Análisis de las Observaciones sub-hora de la Radiación Solar registrada por las Estaciones Meteorológicas Voluntarias de la red MeteoClimatic

    OpenAIRE

    Gutierrez Corea, Federico Vladimir

    2011-01-01

    Enriquecer el conocimiento sobre la Radiación Solar (RS) a nivel del suelo es de gran interés para diferentes aplicaciones meteorológicas entre ellas el área de las energías renovables como la energía solar. La interpolación de observaciones de RS por estaciones en tierra, los sensores remotos y la ejecución de distintos modelos son algunas de las formas que existen para obtener valores de RS con continuidad espacial en el terreno. Aunque se sabe que los mejores valores de RS en la superficie...

  6. Análisis de las Observaciones sub-hora de la Radiación Solar registrada por las Estaciones Meteorológicas Voluntarias de la red MeteoClimatic

    OpenAIRE

    Gutierrez Corea, Federico Vladimir

    2013-01-01

    Enriquecer el conocimiento sobre la Radiación Solar (RS) a nivel del suelo es de gran interés para diferentes aplicaciones meteorológicas entre ellas el área de las energías renovables como la energía solar. La interpolación de observaciones de RS por estaciones en tierra, los sensores remotos y la ejecución de distintos modelos son algunas de las formas que existen para obtener valores de RS con continuidad espacial en el terreno. Aunque se sabe que los mejores valores de RS en la superficie...

  7. Fulltext PDF

    Indian Academy of Sciences (India)

    VIJAY KODIYALAM, R SRINIVASAN and V S SUNDER. Institute of ... In order to define the product PQ, first concatenate the pictures (with P on top and Q at ...... words, ЕRY&ЖИЕSY'Ж, contradicting the hypothesis; hence, indeed R TИ S.

  8. Fulltext PDF

    Indian Academy of Sciences (India)

    The surfeit of books on functional analysis over the years might lead one to believe that the subject has been presented from every possible perspective and in every imaginable style. The appearance of this book by V S. Sunder will quickly dispel that attitude, for in it, the point of view taken, and the choice of ideas described ...

  9. The Impact of Financing Surpluses and Large Financing Deficits on Tests of the Pecking Order Theory

    NARCIS (Netherlands)

    de Jong, Abe; Verbeek, Marno; Verwijmeren, Patrick

    2010-01-01

    This paper extends the basic pecking order model of Shyam-Sunder and Myers by separating the effects of financing surpluses, normal deficits, and large deficits. Using a panel of US firms over the period 1971-2005, we find that the estimated pecking order coefficient is highest for surpluses (0.90),

  10. Resonance – Journal of Science Education | News

    Indian Academy of Sciences (India)

    Glial Cells: The Other Cells of the Nervous System - Oligodendrocytes – Ensheathers of the CNS · Yasmin Khan Medha S Rajadhyaksha · More Details Fulltext PDF. pp 14-26 General Article. On Trace Zero Matrices · V S Sunder · More Details Fulltext PDF. pp 27-38 General Article. Introduction to Web Information Retrieval: ...

  11. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Volume 116 Issue 4 November 2006 pp 443-458 Operator Theory/Operator Algebras/Quantum Invariants. The Planar Algebra of a Semisimple and Cosemisimple Hopf Algebra · Vijay Kodiyalam V S Sunder · More Details Abstract Fulltext PDF. To a semisimple and cosemisimple Hopf algebra over an algebraically closed ...

  12. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences. Vijay Kodiyalam. Articles written in Proceedings – Mathematical Sciences. Volume 110 Issue 3 August 2000 pp 263-292. The Algebra of -relations · Vijay Kodiyalam R Srinivasan V S Sunder · More Details Abstract Fulltext PDF. In this paper, we study a tower { A n G ...

  13. Y chromosomal and sex effects on the behavioral stress response in the defensive burying test in wild house mice

    NARCIS (Netherlands)

    Sluyter, F; Korte, SM; Van Baal, GCM; De Ruiter, AJH; Van Oortmerssen, GA

    1999-01-01

    Genetically selected short attack latency (SAL) and long attack latency (LAL) male wild house mice behave differently in the defensive burying test. When challenged, SAL males respond actively with more time spent on defensive burying, whereas LAL males are more passive with more time remaining

  14. Baltic air wars intensify / Dorian Ziedonis

    Index Scriptorium Estoniae

    Ziedonis, Dorian

    2008-01-01

    Leedu lennufirma FlyLAL pidi maksma ära 40 000 euro suuruse trahvi, et firma lennuk saaks Riia lennuväljalt lahkuda. Varem oli FlyLAL nõudnud Riia Lennujaamalt kompensatsiooni, kuna lennujaam oli võimaldanud Läti lennufirmal airBaltic maksta väiksemaid lennujaamatasusid

  15. Vene tank kui force majeure / Andrei Hvostov

    Index Scriptorium Estoniae

    Hvostov, Andrei, 1963-

    2008-01-01

    Autor on seisukohal, et eestlane ei taha oma ametnikke ülal pidada. Küsimus laieneb tema sõnul eksistentsiaalseks: kas eestlane tahab üldse oma riiki ülal pidada? Rahvas näeb riigis vaid küllusesarve, poliitikud oma ambitsioonide realiseerimise vahendit

  16. The Pilot Staffing Conundrum: A Delphi Study

    Science.gov (United States)

    2009-06-01

    Project, AFIT/ GMO /LAL/98J-2. School of Logistics and Acquisition Management, Air Force Institute of Technology (AU), Wright Patterson AFB, OH, June...Kafer, John H. Relationship of Airline Pilot Demand and Air Force Pilot Retention. Graduate Research Project, AFIT/ GMO /LAL/98J-11. School of Logistics

  17. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. BASANT LAL SHARMA. Articles written in Sadhana. Volume 42 Issue 5 May 2017 pp 713-728. Continuum limit of discrete Sommerfeld problems on square lattice · BASANT LAL SHARMA · More Details Abstract Fulltext PDF. A low-frequency approximation of the discrete Sommerfeld diffraction ...

  18. Clinical Features of Lysosomal Acid Lipase Deficiency

    NARCIS (Netherlands)

    Burton, Barbara K.; Deegan, Patrick B.; Enns, Gregory M.; Guardamagna, Ornella; Horslen, Simon; Hovingh, Gerard K.; Lobritto, Steve J.; Malinova, Vera; McLin, Valerie A.; Raiman, Julian; Di Rocco, Maja; Santra, Saikat; Sharma, Reena; Sykut-Cegielska, Jolanta; Whitley, Chester B.; Eckert, Stephen; Valayannopoulos, Vassili; Quinn, Anthony G.

    2015-01-01

    The aim of this study was to characterize key clinical manifestations of lysosomal acid lipase deficiency (LAL D) in children and adults. Investigators reviewed medical records of LAL D patients ages ≥5 years, extracted historical data, and obtained prospective laboratory and imaging data on living

  19. Learning Pedagogy in Physics

    Science.gov (United States)

    Harlow, Danielle B.; Swanson, Lauren H.; Dwyer, Hilary A.; Bianchini, Julie A.

    2010-10-01

    We report on an adapted version of the Physics and Everyday Thinking (PET) curriculum. A unique aspect of PET is its inclusion of special activities that focus on Learning about Learning (LAL) in which undergraduates analyze videos of children talking about science and explicitly consider the nature of science. To create a course that intentionally linked science content, children's ideas, and strategies for science instruction, we augmented the existing LAL activities with discussions about teaching, and added activities focused on LAL from companion curricula such as Physical Science and Everyday Thinking (PSET) and Learning Physical Science (LEPS). To compensate for the additional time on LAL, we reduced the content activities to only those that directly supported LAL activities. We found that students made significant gains on the CLASS and expressed beliefs about teaching consistent with the PET pedagogy.

  20. Rend og hop - Vi si´r stop

    DEFF Research Database (Denmark)

    Lund, Ole

    Rapporten er en evaluering af projekt Rend og hop som foregik fra 2006 - 2008 i Varde kommune. Projektet bestod af en specifik del og en genrele del, som henholdsvist var et tilbud til overvægtige børn med henblik på at give dem et sundere liv, og et forsøg på at gøre sundhed til en mere dominere......Rapporten er en evaluering af projekt Rend og hop som foregik fra 2006 - 2008 i Varde kommune. Projektet bestod af en specifik del og en genrele del, som henholdsvist var et tilbud til overvægtige børn med henblik på at give dem et sundere liv, og et forsøg på at gøre sundhed til en mere...

  1. Optimering af økologiske produkters kvalitet (QACCP)

    DEFF Research Database (Denmark)

    Lauridsen, Charlotte; Kristensen, Hanne Lakkenborg; Jørgensen, Henry

    2011-01-01

    Forbrugerne efterspørger i stigende grad sundere og mere sikre fødevarer af høj kvalitet, og mange forbrugere har en forventning om, at økologiske fødevarer har højere kvalitet end ikke-økologiske. Det har man hidtil ikke kunnet bevise, bl.a. pga. manglen på videnskabelige undersøgelser af økolog...

  2. Optimal fodring af goldkøer

    DEFF Research Database (Denmark)

    Bjerre-Harpøth, Vibeke; Damgaard, Birthe Marie

    2013-01-01

    Et forsøg har vist, at køer på lavt energiniveau i goldperioden var fysiologisk sundere og havde mindre risiko for at udvikle stofskiftesygdomme end køer på et højt energiniveau. Forsøget viste også, at køer på et normalt energiniveau i senlaktationen gav mere mælk i den efterfølgende laktation e...

  3. Detection of myocardial viability by means of Single Proton Emission Computed Tomography (Perfused SPECT) dual {sup 201} Tl (rest of 15 minutes, 24 late hours and 24 hours reinjection) and gated-SPECT {sup 99m} Tc-SESTAMIBI in effort or stimulation of the coronary reserves; Deteccion de viabilidad miocardica mediante tomografia por emision de foton unico (SPECT perfusorio) dual {sup 201} Talio (Reposo de 15 minutos, 24 horas tardio y 24 horas reinyeccion) y gated-SPECT {sup 99m} Tc-SESTAMIBI en esfuerzo o estimulo de reserva coronaria

    Energy Technology Data Exchange (ETDEWEB)

    Mendoza V, R

    2004-07-01

    The objective of this work was to determine if the images of SPECT {sup 201} TI in rest of 15 minutes, 24 late hours and Gated-SPECT {sup 99m} Tc-SESTAMIBI in effort or stimulation of coronary reservation correlate with the study of 24 hours post reinjection of {sup 201}TI to determine the presence of having knitted viable myocardium. Material and methods: 29 patients were studied with coronary arterial illness (EAC) to who are carried out SPECT {sup 201} TI in rest with images of 15 minutes, 24 late hours and 24 hours reinjection, by means of the administration of {sup 201}TI to dose of 130 MBq and reinjection with 37 MBq. and Gated-SPECT {sup 99m}Tc-SESTAMIBI in effort or stimulation of coronary reservation, later to the administration of 1110 MBq. Results: 29 patients were included according to inclusion approaches and exclusion, of those which 22 (75.86%) they correspond at the masculine sex and 7 (24.13%) to the feminine one, with an average of 62.1 year-old age, 2320 segments myocardial were analysed so much it is phase post-effort as rest; they were diagnosed a total of 264 segments with heart attack, of which viability myocardium was observed in 174 segments. The statistical tests are analysis of frequencies. The non parametric test of Wilcoxon and Mann-Whitney. Conclusions: the viability myocardial at the 24 late hours and 24 hours reinjection was similar; significant difference exists between the study of 15 minutes and 24 hours reinjection, ischemic illness was also demonstrated in territories different to the heart attack area in the studies of 15 minutes, late 24 hours and 24 hours reinjection. (Author)

  4. Limulus amoebocyte lysate test via an open-microcavity optical biosensor

    Science.gov (United States)

    Scudder, Jonathan; Ye, Jing Yong

    2018-02-01

    Almost since its discovery, Limulus amoebocyte lysate (LAL) testing has been an important part of the pharmaceutical quality control toolkit. It allows for in vitro endotoxin testing, which has replaced tests using animals, such as using rabbits' thermal response to judge pyrogenicity of test samples, thus leading to a less expensive and faster test of parenteral pharmaceuticals and medical devices that contact blood or cerebrospinal fluid. However, limited by the detection mechanisms of the LAL assays currently used in industry, further improvement in their performance is challenging. To address the growing demand on optimizing LAL assays for increased test sensitivity and reduced assay time, we have developed an LAL assay approach based on a detection mechanism that is different from those being used in industry, namely, gel-clot, turbidimetric, and chromogenic detection. Using a unique open-microcavity photonic-crystal biosensor to monitor the change in the refractive index due to the reaction between LAL regents and endotoxins, we have demonstrated that this approach has improved the LAL assay sensitivity by 200 times compared with the commercial standard methods, reduced the time needed for the assay by more than half, and eliminated the necessity to incubate the test samples. This study opens up the possibility of using the significantly improved LAL assays for a wide range of applications.

  5. The 1988 to 1989 progress report of the Linear Accelerator Laboratory

    International Nuclear Information System (INIS)

    1990-01-01

    The 1988 to 1989 activity report of the Laboratoire de l'Accelerateur Lineaire (LAL), at Orsay (France), is presented. The LAL research activities are performed in the particle physics field. The studies carried out on the top quark and neutrinos are underlined. The experiments underway and applying the following devices, are summarized: ALEPH, DELPHI, NA31, NA14 ' , UA2 ' , TAU-P, ASTERIX, HIGGS, CELLO and DM2. The planned experiments (Double Beta, Thermistole, H1), the developments, the LAL scientific activities and the list of published papers are included [fr

  6. Effects of laser-assisted lipolysis on nipple-areola complex.

    Science.gov (United States)

    Sönmez Ergün, Selma; Kayan, Reşit Burak; Güleş, Mustafa Ekrem; Kuzu, İsmail Melih

    2017-08-01

    Gynecomastia, as a most common benign condition, represents itself as the enlargement of the male breast and also nipple-areola complex as the severity of the condition increases. With this study, we aimed to clarify the effects of 980-nm diode laser on nipple-areola complex (NAC). Although numerous open techniques have been described to correct gynecomastia, nowadays trends have shifted to minimally invasive techniques such as laser-assisted lipolysis (LAL). A total of 25 patients with bilateral gynecomastia treated with LAL by using a 980-nm diode laser. The resultant contour and reduced size of the complex were satisfactory. LAL leads to significant reduction of the size of NAC.

  7. ESTUDO DO COMPORTAMENTO DA CREATINO QUINASE (CK E CREATINO QUINASE-MB (CK-MB SÉRICA DE CÃES SUBMETIDOS À OXIGENAÇÃO POR MEMBRANA EXTRACORPÓREA (ECMO DURANTE UM PERÍODO DE TRÊS HORAS

    Directory of Open Access Journals (Sweden)

    Felipp Silveira Ferreira

    2010-10-01

    Full Text Available The extracorporeal membrane oxygenation (ECMCMO is a technique of prolonged cardiopulmonary support, which aims to help the lungs or the heart when these organs present failure processes not responsive to conventional treatments. As it is not a physiological procedure, it represents a major challenge for medicine, which seeks to make it a safer procedure. Thus, this research was carried out to determine the course of the cardiac markers CK and CK-MB of five dogs submitted at ECMO for three hours. Mongrel dogs of various ages, weight and sex were used. Under anesthesic maintenance, the animals were subjected to femoral cannulation for ECMCMO, in an arterial-venous (AV deviation. Once the circuit was established, the variables were measured every thirty minutes for a period of three hours. The data were statistically analyzed with Anova, Tukey and Pearson Correlation, with α = 5%. The results showed an increase of serum CK and CK-MB, characterizing a muscular injury during the procedure. The results showed that ECMO induced a cardiac muscle injury by a physiological mechanism. It was concluded that ECMCMO is a viable technical support and do not induce myocardial injury in dogs during a period of three hours.

  8. Student-Teachers' Teaching Techniques: Actors in Pupils' Extrinsic Motivation as They Speak (Técnicas de enseñanza de los docentes practicantes: actores en la motivación extrínseca de los estudiantes a la hora de hablar)

    Science.gov (United States)

    Báez Dueñas, Leidy Tatiana; Chacón Vargas, Leidy Marcela

    2013-01-01

    This article describes a research project we carried out in order to study the role of student-teachers' teaching techniques as regards their pupils' extrinsic motivation as they partake in communicative speaking activities at a public school in Tunja, Colombia. Data were gathered by means of field notes, focus groups and student-teachers'…

  9. Correlation of the glomerular filtration rate by the Gates scintigraphy method and by the creatinine purification in urine of 24 hours; Correlacion de la tasa de filtracion glomerular por el metodo gamagrafico de Gates y por la depuracion de creatinina en orina de 24 horas

    Energy Technology Data Exchange (ETDEWEB)

    Gomez A, E

    2003-07-01

    The kidney is an important organ that makes that exist equilibrium inside the organism. In it' s multiple functions, one that interests us to know is the glomerular filtration rate (GFR). To know this, exist laboratory and scintigraphy studies like the scintigraphy with technique of Gates and the creatinine purification in urine of 24 hours. The files of 44 patients were studied, which were clinically candidates to kidney donors healthy (25 women and 19 men) with ages that varied from the 18 years to the 54 years ( 35.1 years), with a weight of 43 kilograms to 94 kilograms (68.95 Kg) and with a corporal surface of 1.29 to 2.08 m{sup 2} (1.70 m{sup 2}). These patients underwent study protocols with creatinine purification and with renal scintigraphy. The glomerular filtration rate obtained by creatinine purification varied from 51.9 ml/min. to 156 ml/min. and the GFR obtained by scintigraphy varied from 3.6 ml/min. to 155.2 ml/min. Once obtained the gathering of data the test of Student was applied to compare the averages of both distributions and the analysis of lineal regression to determine the coefficients of correlation of the complete group. (Author)

  10. Influência do alongamento passivo em três repetições de 30 segundos a cada 48 horas em músculo sóleo imobilizado de ratos Influence of passive stretching in three 30-second sets at every 48 hours in immobilized soleum muscle of rats

    Directory of Open Access Journals (Sweden)

    Thiago Menon

    2007-12-01

    Full Text Available O músculo esquelético tem a propriedade de adaptar-se a diferentes estímulos, alterando o número de sarcômeros em série, de acordo com o comprimento a que está submetido. Este trabalho tem como objetivo comparar as adaptações de peso e comprimento do músculo sóleo de ratos, além de estimativa do total de sarcômeros em série, quando submetidos a alongamento intermitente durante imobilização em plantiflexão. Foram utilizados 24 ratos (Wistar machos de 14 ± 2 semanas de idade, divididos em 4 grupos: C (n = 6 - controle; A (n = 6 - músculo sóleo esquerdo (MSE alongado; I - (n = 6 MSE imobilizado; IA (n = 6 MSE imobilizado e alongado. O protocolo utilizado foi 3 séries de alongamento com duração de 30s a cada 48h; e período total de imobilização de 21 dias. Foram comparadas as variações observadas entre os músculos sóleus direito (MSD e o MSE com relação a peso muscular, comprimento muscular e estimativa do número de sarcômeros em série (ENSS, através da contagem em 300mm. Nas variáveis analisadas ao comparar o MSD (controle e o MSE (submetido a alongamento e/ou imobilização foram observados: peso muscular: C = -1,59%, (p = 0,67; A = +5,41% (p = 0,05; I = -41,48% (p = 0,01; IA = -32,46% (p = 0,01; comprimento muscular: C = -2,63% (p = 0,43; A = +7,54% (p = 0,07; I = -12,74% (p = 0,01; IA = -10,42% (p = 0,11; ENSS: C = -3,81% (p = 0,09; A = + 2,73% (p = 0,56; I = -12,20% (p = 0,01; IA = -12,21% (p = 0,21. Conclui-se que o alongamento durante a imobilização preservou o comprimento muscular e a quantidade de sarcômeros em série, mas não evitou a perda do peso muscular.The skeletal muscle has the property to adapt to different stimuli, alternating the number of sarcomeres in series, according to the length to which it is submitted to. This investigation has the aim to compare weight and length adaptations of the soleus muscle in rats, besides the total estimate of the sarcomeres in series, when submitted to intermittent stretching during immobilization in plantarflexion. Twenty-four 14 ± 2 weeks old Wistar male rats were used. They were divided in 4 groups, namely: C (n = 6 - control; A (n = 6 - stretched left soleus muscle (LSM; I (n = 6 - immobilized left soleus muscle; IA (n = 6 - immobilized and stretched LSM. The used protocol was of 3 stretching sets with 30 s duration at every 48 h, and total immobilization period of 21 days. The variations observed were compared between right soleus muscle (RSM and LSM concerning muscular weight, muscular length and estimate of number of sarcomeres in series (ENSS, through counting in 300 mm. In the analyzed variables, when RSM (control and LSM were compared (submitted to stretching and/or immobilization the following were observed: muscular weight: C = -1.59% (p = 0.67; A = +5.41% (p = 0.05; I = -41.48% (p = 0.01; IA = -32.46% (p = 0.01; muscular length: C = -2.63% (p = 0.43; A = +7.54% (p = 0.07; I = -12.74% (p = 0.01; IA = -10.42% (p = 0.11; ENSS: C = -3.81% (p = 0.09; A = +2.73% (p = 0.56; I = -12.20% (p = 0.01; IA = -12.21% (p = 0.21. It is concluded that stretching during immobilization has preserved muscular length and the amount of sarcomeres in series; however, it did not prevent muscular weight loss.

  11. Dům mrtvých, nebo dům živých? Laténský objekt s lidskými kostrami z Nových Dvorů, okr. Kutná Hora

    Czech Academy of Sciences Publication Activity Database

    Šumberová, Radka; Valentová, J.

    2011-01-01

    Roč. 63, č. 2 (2011), s. 220-250 ISSN 0323-1267 Institutional research plan: CEZ:AV0Z80020508 Keywords : La Tène period * Central Bohemia * rites of passage * multi-phase burial * ditch enclosure * exposition Subject RIV: AC - Archeology, Anthropology, Ethnology

  12. Error Estimation for the Linearized Auto-Localization Algorithm

    Directory of Open Access Journals (Sweden)

    Fernando Seco

    2012-02-01

    Full Text Available The Linearized Auto-Localization (LAL algorithm estimates the position of beacon nodes in Local Positioning Systems (LPSs, using only the distance measurements to a mobile node whose position is also unknown. The LAL algorithm calculates the inter-beacon distances, used for the estimation of the beacons’ positions, from the linearized trilateration equations. In this paper we propose a method to estimate the propagation of the errors of the inter-beacon distances obtained with the LAL algorithm, based on a first order Taylor approximation of the equations. Since the method depends on such approximation, a confidence parameter τ is defined to measure the reliability of the estimated error. Field evaluations showed that by applying this information to an improved weighted-based auto-localization algorithm (WLAL, the standard deviation of the inter-beacon distances can be improved by more than 30% on average with respect to the original LAL method.

  13. Teaching Hiroshima: Thinking about the Unthinkable.

    Science.gov (United States)

    Dyke, Reg

    1983-01-01

    Describes the instructional materials used in a sophomore literature course to deal with the topic of possible nuclear destruction, including John Hersey's "Hiroshima"; photographs of Hiroshima and Nagasaki; Carl Sagan's "Cosmos"; and specially prepared handouts and worksheets. (LAL)

  14. Study of an automatic readout integrated circuit for the signal shaping of the ATLAS electromagnetic calorimeter; Etude d`un circuit integre de commutation automatique de gain pour le circuit de mise en forme du signal du calorimetre electromagnetique d`ATLAS

    Energy Technology Data Exchange (ETDEWEB)

    Bussat, J.M. [Laboratoire d`Annecy-le-Vieux de Physique des Particules, 74 - Annecy-le-Vieux (France)

    1996-12-01

    This paper describes the present state of the development of an automatic readout integrated circuit that can be used, connected to the four gain shaper of LAL, at the ATLAS electromagnetic calorimeter.

  15. Limestone cliff - face and cave use by wild ring-tailed lemurs ( Lemur ...

    African Journals Online (AJOL)

    ... FP Cuozzo, IA Youssouf Jacky, KD Fish, M LaFleur, LAL Ravelohasindrazana, JF Ravoavy ... This work is documenting newly discovered behaviors by this species. ... variation and increasing threats to this endangered primate species.

  16. Summer Appendicitis

    African Journals Online (AJOL)

    hanumantp

    The increasing number of “fast food” restaurants where mainly high‑carbohydrate ... factors, food culture and the effect of migration for touristic purposes during the summer. .... Lal A, Hales S, French N, Baker MG. Seasonality in human.

  17. Lean Enterprise Value Phase

    National Research Council Canada - National Science Library

    Shields, John T

    2005-01-01

    ... using a philosophy called "lean." LAl's mission is to research, develop, and promulgate practices, tools, and knowledge that enable and accelerate the envisioned transformation of the greater US aerospace enterprise through people and processes...

  18. The planes are back / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2009-01-01

    2009. aasta alguses pankrotistus Leedu lennufirma FlyLAL, kuid novembris selgus, et Air Baltic ja Leedu lennukompanii Star1 Airlines alustavad uute regulaarlendudega Vilniusest. Leedus on 3 rahvusvahelist lennujaama

  19. Manitowoc R UVDOC data 2011

    Data.gov (United States)

    U.S. Environmental Protection Agency — Manitowoc R UVDOC data 2011. This dataset is associated with the following publication: Williamson, C., S. Madronich, A. Lal, R. Zepp, R. Lucas, E. Overholt, K....

  20. Orsay: High-gradient experiment

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Maintaining the tradition of its contribution to the LEP Injector Linac (LIL), Orsay's Linear Accelerator Laboratory (LAL) is carrying out an R&D programme entitled 'New accelerator physics experiments at LAL' (NEPAL). The aim is to contribute to the long-term development of high energy electron-positron linear colliders, where progress can be of short-term benefit both to conventional accelerators and to injectors in rings or free-electron lasers

  1. The great tsunami of 26 December 2004: A description based on tide gauge data from Indian subcontinent and surrounding areas

    Digital Repository Service at National Institute of Oceanography (India)

    Nagarajan, B.; Suresh, I; Sundar, D.; Sharma, R; Lal, A.K.; Neetu, S.; Shenoi, S.S.C.; Shetye, S.R; Shankar, D.

    -1 Earth Planets Space, 58, 211?215, 2006 The Great Tsunami of 26 December 2004: A description based on tide-gauge data from the Indian subcontinent and surrounding areas B. Nagarajan1, I. Suresh2, D. Sundar2, R. Sharma1,A.K.Lal1, S. Neetu2, S. S. C. Shenoi..., I. Suresh, D. Sundar, R. Sharma, A. K. Lal, S. Neetu, S. S. C. Shenoi, S. R. Shetye, and D. Shankar (e-mail: shankar@nio.org) ...

  2. Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics

    OpenAIRE

    Aguisanda, Francis; Yeh, Charles D.; Chen, Catherine Z.; Li, Rong; Beers, Jeanette; Zou, Jizhong; Thorne, Natasha; Zheng, Wei

    2017-01-01

    Background Wolman disease (WD) is a rare lysosomal storage disorder that is caused by mutations in the LIPA gene encoding lysosomal acid lipase (LAL). Deficiency in LAL function causes accumulation of cholesteryl esters and triglycerides in lysosomes. Fatality usually occurs within the first year of life. While an enzyme replacement therapy has recently become available, there is currently no small-molecule drug treatment for WD. Results We have generated induced pluripotent stem cells (iPSCs...

  3. Molecular and Cellular Mechanisms of Septic Shock

    Science.gov (United States)

    1988-03-01

    due to gastric dilation - volvulus (6Y). The LAL-chromogenic procedure iýs sensitive and reliable for detecting plasma LPS. LPS has a short initial T 1/2...portal injections of endotoxin. and intestinal ischemia. Endotoxin (LPS) was quantitated in canine plasma using the Limulus amebocyte lysate (LAL...CV=1O), and stability of diluted, heat-treated, frozen samples (at least 8 wk). Analysis of canine plasma samples following sublethal IV (jugular or

  4. [Epidemiological, clinical, cytologic and immunophenotypic aspects of acute leukemia in children: the experience at the hematology laboratory of IBN SINA University Hospital Center].

    Science.gov (United States)

    Doumbia, Mariam; Uwingabiye, Jean; Bissan, Aboubacar; Rachid, Razine; Benkirane, Souad; Masrar, Azlarab

    2016-01-01

    The aim of this study was to describe epidemiological, cytologic and immunophenotypic aspects of acute leukemias (AL) in children diagnosed at IBN SINA University Hospital Center and to determine the concordance between cytology and immunophenotyping results. This is a cross-sectional study conducted in the hematology laboratory of IBN SINA University Hospital Center between June 2012 and May 2014. Among the 104 cases with diagnosed AL, 52% were boys with a sex-ratio H/F= 1.32, the average age was 5.7 years. The distribution of different types of AL was: lymphoid AL (LAL) (74%), myeloid (AML) (20.2%), biphenotypic AL (BAL) (65.8%). Among the LALs, 78% were classified as B LAL and 22% as T LAL. Clinical signs were mainly presented with tumor syndrome (73.1%), fever (61%) and hemorrhagic syndrome (50%). The most common blood count abnormalities were: thrombopenia (89.4%), anemia (86.5%), hyperleukocytosis (79.8%). The rate of peripheral and bone marrow blasts was statistically higher for LAL than for AML and BAL (p <0.001). The rate of relapse and mortality was 21.2% and 16. 3% respectively. Concordance rate between the results of cytology and of immunophenotyping was 92.7% for LAL and 82.6% for AML. Diagnosis of AL is always based primarily on cytology. Immunophenotyping allowed us to make a better distinction between acute leukemias. The management of paediatric AL is a major health problem which requires specialized care centers.

  5. Progress report 2001-2002

    International Nuclear Information System (INIS)

    2003-01-01

    The document reviews the activities of the linear accelerator laboratory (LAL) for the years 2001 and 2002. Most part of these activities are active collaborations in international programs. Some experimental programs like Aleph (apparatus for Lep physics) and Delphi (detector with lepton, photon, and hadron identification) at the Lep (CERN) or Na48 (search for direct violation of the CP invariance) have entered their last stage. Others like H1 (electron-positron experiment at Hera), Babar (measurement of CP violation in the B 0 B-bar 0 system) at Slac (Stanford), or D0 (search for new particles at the Tevatron) at Fermilab, are fully operating and this document describes the contribution of the LAL for each of them. The preparation of experiments for the future LHC has represented the core of LAL's technical activities. This document reviews these activities and achievements for the Atlas (air toroid LHC apparatus system) and LHCB (large hadron collider beauty) experiments. The LAL is also involved in the definition of the future high energy linear electron-positron collider (FLC). The LAL contributes to some experiments of neutrino physics through Nemo (violation of the lepton charge) and Opera (neutrino oscillations) experiments and to various astro-particles experiments such as Eros (micro-lensing effect), Archeops and Planck (cosmology), Virgo (gravitation waves) and Auger (very high energy particles showers). Another important part of LAL's activities is teaching activity mainly inside the curriculum of Paris-sud university. (A.C.)

  6. Progress report 2001-2002; Rapport d'activite 2001-2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The document reviews the activities of the linear accelerator laboratory (LAL) for the years 2001 and 2002. Most part of these activities are active collaborations in international programs. Some experimental programs like Aleph (apparatus for Lep physics) and Delphi (detector with lepton, photon, and hadron identification) at the Lep (CERN) or Na48 (search for direct violation of the CP invariance) have entered their last stage. Others like H1 (electron-positron experiment at Hera), Babar (measurement of CP violation in the B{sup 0}B-bar{sup 0} system) at Slac (Stanford), or D0 (search for new particles at the Tevatron) at Fermilab, are fully operating and this document describes the contribution of the LAL for each of them. The preparation of experiments for the future LHC has represented the core of LAL's technical activities. This document reviews these activities and achievements for the Atlas (air toroid LHC apparatus system) and LHCB (large hadron collider beauty) experiments. The LAL is also involved in the definition of the future high energy linear electron-positron collider (FLC). The LAL contributes to some experiments of neutrino physics through Nemo (violation of the lepton charge) and Opera (neutrino oscillations) experiments and to various astro-particles experiments such as Eros (micro-lensing effect), Archeops and Planck (cosmology), Virgo (gravitation waves) and Auger (very high energy particles showers). Another important part of LAL's activities is teaching activity mainly inside the curriculum of Paris-sud university. (A.C.)

  7. Comparison of Cellular Alterations in Fat Cells Harvested With Laser-Assisted Liposuction and Suction-Assisted Liposuction.

    Science.gov (United States)

    Yildiz, Kemalettin; Taşli, Pakize Neslihan; Şahin, Fikrettin; Güneren, Ethem

    2016-05-01

    The aim of the present study was to evaluate the viability and proliferative capacity of adipose-derived stem cells obtained by laser-assisted liposuction (LAL). Fat tissue was obtained from 7 male patients treated surgically for gynecomastia. On one side, harvesting was made before LAL, while it was implemented after LAL on the contralateral side. Viability, cell surface antigens, pluripotency, and apoptosis were assessed and compared in these samples. Cells harvested before and after LAL did not exhibit any significant difference in terms of surface cell markers. Number of viable stem cells was lower initially after exposure to laser, while this difference was reversed at the end of 72 hours. Genetic indicators of cellular differentiation were similar in both groups. Apoptosis indicators were increased remarkably after laser exposure in the first 24 hours, but this increase was absent 72 hours after LAL procedure. The authors' results have promising clinical relevance since mesenchymal stem cells harvested during LAL have maintained appropriate cellular features to be used for autologous fat transfer and fat grafting.

  8. Laser-Assisted Liposuction Using the Novel 1,444-nm Nd:YAG Laser for the Treatment of Gynecomastia: A Pilot Study.

    Science.gov (United States)

    Yoo, Kwang Ho; Bae, Jung Min; Won, Chae Young; Chung, Yu Seok; Goo, Boncheol; Rho, Yong Kwan; Kim, Gyong Moon; Lee, Jongwon; Ahn, Byeong Heon; Kim, Beom Joon

    2015-01-01

    Laser-assisted liposuction (LAL) is currently widely used to reduce localized fat. A novel Nd:YAG laser that uses a wavelength of 1,444 nm, which is better absorbed by fat, has recently been introduced. In this study, we investigated the efficacy of 1,444-nm Nd:YAG LAL for the treatment of gynecomastia. Thirteen Korean male patients (20-28 years, mean age 23 years) diagnosed with gynecomastia were enrolled in this study. All patients were treated by LAL with 1,444-nm Nd:YAG laser (100 µs pulse width, 40 Hz frequency, 300 mJ pulse energy and 12 W power with continuous emission) after tumescent anesthetic infiltration and were then evaluated. Outcome was assessed using the following 4 methods: (1) clinical assessment with photographs obtained before and 12 weeks after LAL treatment, (2) comparison of pre- and postoperative patient chest circumferences, (3) computed tomography (CT) scans to evaluate changes in breast thickness and (4) a patient satisfaction survey at the end of the study. After 12 weeks, most patients (84.5%) showed an improvement greater than 50%. Mean chest circumference was significantly reduced from 109.6 ± 8.2 to 101.2 ± 4.4 cm 12 weeks after LAL (p Gynecomastia can be safely treated with 1,444-nm Nd:YAG LAL to reduce fatty tissue and total breast volume. © 2015 S. Karger AG, Basel.

  9. Estudio ultraestructural de la fagocitosis de promastigotes y amastigotes de Leishmania mexicana por la línea de células dendríticas FSDC

    Directory of Open Access Journals (Sweden)

    Ladys Sarmiento

    2006-10-01

    Full Text Available Introducción. Las células dendríticas están presentes en la mayoría de los tejidos, ellas capturany presentan antígenos para activar a los linfocitos T. Objetivo. Se describe ultraestructuralmente la fagocitosis de Leishmania mexicana por lalínea de células dendríticas FSDC, una línea de células de Langerhans obtenida de la epidermisfetal de ratón, e inmortalizada por la transducción retroviral del oncogen v-myc. Materiales y métodos. Se obtuvieron amastigotes de la lesión de ratones Balb/c y promastigotesa partir del cultivo (24°C de la lesión. Las FSDC se cultivaron con los parásitos en unaproporción de 5 parásitos por célula, en medio IMDM, durante 24 horas. Los cultivos infectadosy los controles se procesaron para microscopía electrónica de transmisión. Se hicieron cortessemifinos contrastados con azul de toluidina para evaluar porcentaje de fagocitosis y finos,contrastados con acetato de uranilo y citrato de plomo. Resultados. El 13,42% de las FSDC fagocitaron promastigotes; de ellas el 8% contenían unparásito y el restante 5,2% fagocitó dos o más. El 20% de las FSDC fagocitaron amastigotes;10% contenían un parásito y 10% dos o más. Ultraestructuralmente se observaron promastigotesen contacto con las células por el flagelo o por el polo posterior. Los fagosomas que conteníanpromastigotes eran organelos estrechos con uno ó dos parásitos. Los que conteníanamastigotes eran de gran tamaño (8 μm con uno o varios parásitos, libres o adosados a lamembrana del fagosoma por su polo posterior. Conclusión. La infección de las FSDC se caracterizó por una baja tasa de células infectadasal ser expuestas a promastigotes o amastigotes. La vacuola parasitofora presentó característicassimilares a las de los macrófagos. En su mayoría las FSDC presentaban 1 a 3 parásitos porcélula. Las observaciones plantean la necesidad de estudiar la relación entre capacidad defagocitosis y función.

  10. Environmental set-up and tidal propagation in a tropical estuary with dual connection to the sea (SW Coast of India)

    Digital Repository Service at National Institute of Oceanography (India)

    Revichandran, C.; Srinivas, K.; Muraleedharan, K.R.; Rafeeq, M.; Shivaprasad, A.; Vijayakumar, K.; Jayalakshmy, K.V.

    at the Proudman Oceanographic Laboratory, UK (Bell et al., 2000). The present paper largely follows the techniques described in Sunder and Shetye., 2005, where the tidal propagation in Mandovi-Zuari estuarine network was studied using one month WL data at 13... rivers is estimated to be 22.41 X10 3 Mm 3 . Runoff is not uniformly distributed; 60-70 % of the runoff is during the SW monsoon period (June-September), while during the pre-monsoon period (April-May) virtually there was no significant runoff. Table...

  11. Evidence-Based Practice in Liposuction.

    Science.gov (United States)

    Collins, Patrick S; Moyer, Kurtis E

    2018-01-24

    The goal of this study is to examine the existing peer reviewed literature comparing modern adjunctive techniques in liposuction including laser-assisted liposuction (LAL) and ultrasound-assisted liposuction (UAL) to standard suction-assisted liposuction (SAL). We intend to interpret these findings into a literature-based clinical application to influence practice patterns. A literature review was conducted using a keyword search in PubMed. Keyword search items included liposuction, lipoplasty, suction assisted liposuction, ultrasound assisted liposuction, laser assisted liposuction, tumescent, liposuction comparison, liposuction review, and combinations therein. Exclusion criteria included articles with a primary focus on histologic effects of energy devices, primary animal models, primary opinion papers with no reference to available data, and industry-sponsored publications. Inclusion criteria included articles with direct comparison of liposuction modalities, randomized or blinded studies, and studies with objective outcomes. Twenty-five articles that met the inclusion criteria comparing SAL to UAL or LAL out of 9972 articles identified were obtained. The selected literature was assigned into 3 categories: evidence demonstrating an advantage of 1 modality (SAL, UAL, or LAL) over another, evidence that showed no benefit of 1 modality over another, and evidence that demonstrated risks of complications of 1 modality over another. The benefits of UAL and LAL over SAL include the following: (1) UAL over SAL in the treatment of gynecomastia, (2) LAL and UAL over SAL with decreased hemoglobin/hematocrit in high-volume lipoaspirates, and (3) LAL over SAL with skin tightening in select areas specifically the submental area. Otherwise, the literature demonstrates equivocal results among the described techniques with no clear benefit to set one apart from the other. There appears to be no demonstrable added benefit to the addition of either UAL or LAL that would urge a

  12. Dose-dependent utilisation of casein-linked lysinoalanine, N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine in rats.

    Science.gov (United States)

    Somoza, Veronika; Wenzel, Elisabeth; Weiss, Carola; Clawin-Rädecker, Ingrid; Grübel, Nadine; Erbersdobler, Helmut F

    2006-09-01

    During the heat treatment of protein-containing foods, the amino acid lysine is most prone to undergo chemical reactions in the course of amino acid cross-linking or Maillard reactions. Among the reaction products formed, lysinoalanine (LAL), N(epsilon)-fructoselysine (FL) and N(epsilon)-carboxymethyllysine (CML) are those which serve as sensitive markers for the heat treatment applied. From a nutritional perspective, these compounds are ingested with the diet in considerable amounts but information about their metabolic transit and putative in vivo effects is scarce. In the present study, casein-linked LAL, FL and CML were administered to rats in two different doses for 10 days. Quantitation of LAL, FL and CML in plasma, tissue and faeces samples revealed that the kidneys are the predominant sites of accumulation and excretion. The maximum percent of dietary LAL, FL and CML excreted in the urine was 5.6, 5.2 and 29%, whereas the respective recoveries in the kidneys were 0.02, 26 and 1.4%. The plasma and tissue analyses revealed that the endogenous load of either compound is increased by its dietary intake. But the dose-dependent utilisation of dietary protein-linked LAL, FL and CML in rats has been demonstrated for the first time to vary substantially from each other.

  13. Counting The Cats In Zanzibar: American Travel Abroad in American Travel Writing to 1914 Counting The Cats In Zanzibar: American Travel Abroad in American Travel Writing to 1914

    Directory of Open Access Journals (Sweden)

    Terry Caesar

    2009-09-01

    Full Text Available In 1914 Josiah Royce began his address to a scientific gathering by comparing philosophy to "a sort of Cook's bureau." "Its servants," Royce continued, "are taught to speak various languages -- all of them ill -- and to know little of the inner life of the numerous foreign lands to which they guide their feet, or check the luggage of their fellow men." Yet these agents have their use, Royce concluded, "if new comparative studies of ideas of various and widely sundered provinces of research are to be carried out at all," and he bid his listeners to regard him, "if you wish to vary the name, as representing some bureau of university travel." In 1914 Josiah Royce began his address to a scientific gathering by comparing philosophy to "a sort of Cook's bureau." "Its servants," Royce continued, "are taught to speak various languages -- all of them ill -- and to know little of the inner life of the numerous foreign lands to which they guide their feet, or check the luggage of their fellow men." Yet these agents have their use, Royce concluded, "if new comparative studies of ideas of various and widely sundered provinces of research are to be carried out at all," and he bid his listeners to regard him, "if you wish to vary the name, as representing some bureau of university travel."

  14. Detection of endotoxins in radiopharmaceutical preparations. III. Limulus test assessment using radiopharmaceutical preparations; correlation with the rabbit pyrogen test

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Y; Bahri, F; Bruneau, J; Dubuis, M; Dubuis, N; Merlin, L; Michaud, T; Peysson, S

    1986-01-01

    Experiments using 17 radiopharmaceuticals containing known amounts of added endotoxin show that none of them inhibits the pyrogenic reaction of the rabbit. Gelation of the Limulus amoebocyte lysate (LAL) is inhibited by 4 of them: colloidal erbium 169Er citrate, colloidal rhenium 186Re sulfide, colloidal technetium /sup 99m/Tc (Re) sulfide for liver scintigraphy and the colloidal technetium /sup 99m/Tc (Re) sulfide for lymphography. This inhibition is cancelled, either by dilution or after neutral pH adjustment. Both controls were performed on 313 batches of various radiopharmaceuticals, 95% of results were identical (93% negative, 2% positive). The remaining 5% correspond to positive LAL tests vs negative rabbit tests on the same batches. No negative LAL test vs positive rabbit test was observed.

  15. [Effect of thyroid hormones on the histotopography of lectin receptors in the rat salivary gland].

    Science.gov (United States)

    Lutsik, A D; Iashchenko, A M; Detiuk, E S

    1987-04-01

    Using lectin-peroxidase technique, the influence of hypo- and hyperthyroidism on histotopography of glycoconjugates has been investigated in rat submandibular gland. The following lectins were used: peanut agglutinin (PNA), wheat germ agglutinin (WGA), Laburnum anagyroides lectin (LAL) and concanavalin A (con A). It has been demonstrated that hyperthyroidism is accompanied by the loss of con A, WGA and LAL receptor sites. Hypothyrodism enhanced con A binding to granular duct cells with a parallel reduction in WGA and LAL binding to these or other duct cells. Hypothyroidism as well as hyperthyroidism markedly enhanced PNA binding to duct epitheliocytes with redistribution of these lectin binding sites from the luminal surface of salivary ducts into the cytoplasm of duct cells. Possible interpretations of the observed phenomena are discussed.

  16. Progress report 2001-2002; Rapport d'activite 2001-2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The document reviews the activities of the linear accelerator laboratory (LAL) for the years 2001 and 2002. Most part of these activities are active collaborations in international programs. Some experimental programs like Aleph (apparatus for Lep physics) and Delphi (detector with lepton, photon, and hadron identification) at the Lep (CERN) or Na48 (search for direct violation of the CP invariance) have entered their last stage. Others like H1 (electron-positron experiment at Hera), Babar (measurement of CP violation in the B{sup 0}B-bar{sup 0} system) at Slac (Stanford), or D0 (search for new particles at the Tevatron) at Fermilab, are fully operating and this document describes the contribution of the LAL for each of them. The preparation of experiments for the future LHC has represented the core of LAL's technical activities. This document reviews these activities and achievements for the Atlas (air toroid LHC apparatus system) and LHCB (large hadron collider beauty) experiments. The LAL is also involved in the definition of the future high energy linear electron-positron collider (FLC). The LAL contributes to some experiments of neutrino physics through Nemo (violation of the lepton charge) and Opera (neutrino oscillations) experiments and to various astro-particles experiments such as Eros (micro-lensing effect), Archeops and Planck (cosmology), Virgo (gravitation waves) and Auger (very high energy particles showers). Another important part of LAL's activities is teaching activity mainly inside the curriculum of Paris-sud university. (A.C.)

  17. Inactivation of gram-negative bacteria in milk and banana juice by hen egg white and lambda lysozyme under high hydrostatic pressure.

    Science.gov (United States)

    Nakimbugwe, Dorothy; Masschalck, Barbara; Anim, Grace; Michiels, Chris W

    2006-10-15

    The effect of hen egg white lysozyme (HEWL) and bacteriophage lambda lysozyme (LaL) in combination with high pressure (HP) treatment on the inactivation of four gram-negative bacteria (Escherichia coli O157:H7, Shigella flexneri, Yersinia enterocolitica and Salmonella typhimurium), was studied in skim milk (pH 6.8; a(w) 0.997) and in banana juice (pH 3.8; a(w) 0.971). In the absence of lysozymes, S. flexneri was more sensitive to HP in milk than in banana juice, while the opposite was observed for the other three bacteria. In combination with HP treatment, LaL was more effective than HEWL on all bacteria in both milk and banana juice. Depending on the bacteria, inactivation levels in banana juice were increased from 0.4-2.7 log units by HP treatment alone to 3.6-6.5 log units in the presence of 224 U/ml LaL. Bacterial inactivation in milk was also enhanced by LaL but only by 0.5-2.1 log units. Under the experimental conditions used, LaL was more effective in banana juice than in milk, while the effectiveness of HEWL under the same conditions was not significantly affected by the food matrix. This effect could be ascribed to the low pH of the banana juice since LaL was also more effective on E. coli in buffer at pH 3.8 than at pH 6.8. Since neither LaL nor HEWL are enzymatically active at pH 3.8, we analysed bacterial lysis after HP treatment in the presence of these enzymes, and found that inactivation proceeds through a non-lytic mechanism at pH 3.8 and a lytic mechanism at pH 6.8. Based on these results, LaL may offer interesting perspectives for use as an extra hurdle in high pressure food preservation.

  18. A comparative study of Mono Mac 6 cells, isolated mononuclear cells and Limulus amoebocyte lysate assay in pyrogen testing

    DEFF Research Database (Denmark)

    Moesby, Lise; Jensen, S; Hansen, E W

    1999-01-01

    ) and Staphylococcus aureus was comparable to that of MNC. Aspergillus niger and Candida albicans induced IL-6 in isolated MNC, but not in MM6. The detection limit for Salmonella typhimurium in the MM6 assay was comparable to that of the LAL assay. As expected, S. aureus and C. albicans did not show any LAL activity......Pyrogen induced secretion of interleukin 6 (IL-6) in Mono Mac 6 (MM6) cells was measured. The ability of the MM6 cell culture to detect pyrogens was compared to the Limulus amoebocyte lysate (LAL) test and isolated mononuclear cells (MNC). The detection limit of MM6 for lipopolysaccharide (LPS....... A. niger and Influenza virus showed some activity in the LAL test, but could not be detected by MM6 cells. In conclusion, the MM6 assay is a good supplement to the current pyrogen assays for detection of LPS, S. aureus and S. typhimurium, but the MM6 assay could not detect A. niger, C. albicans...

  19. ACKNOWLEDGEMENTS

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    P K Gupta, Roorkee. Boris Gurevich, Australia. Simon Harley, Edinburgh, Scotland. Anand K Inamdar, California. A Jayaraman, Ahmedabad. K N Khattri, Dehradun. Ralf Kretz, Canada. S Krishnaswami, Ahmedabad. R K Lal, Varanasi. D C Mishra, Hyderabad. Asoke Mookherjee, Kolkata. Dhruba Mukhopadhyay, Kolkata.

  20. jfewr ©2017 - jfewr Publications

    African Journals Online (AJOL)

    Adams Chaskda

    Lal and Stewart 1990;. Van der Warf, and Petit, 2002; Kyba et al., 2014). Also, to ..... Farris Z.J.; Golden, C.D.; Karpanty, S.; Murphy,. A.; Stauffer, D.; Ratelolahy, F. Andrianjakarivelo, V.; Holmes, C.M. and. Kelly M.J. (2015). Hunting, Exotic.

  1. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Astrophysics and Astronomy. P. Kharb. Articles written in Journal of Astrophysics and Astronomy. Volume 37 Issue 4 December 2016 pp 34 Review. From Nearby Low Luminosity AGN to High Redshift Radio Galaxies: Science Interests with Square Kilometre Array · P. Kharb D. V. Lal V. Singh J.

  2. Mamta Pandey-Pommier

    Indian Academy of Sciences (India)

    Pommier. Articles written in Journal of Astrophysics and Astronomy. Volume 37 Issue 4 December 2016 pp 31 Review. Clusters of Galaxies and the Cosmic Web with Square Kilometre Array · Ruta Kale K. S. Dwarakanath Dharam Vir Lal Joydeep ...

  3. Transversals in non-discrete groups

    Indian Academy of Sciences (India)

    Transversals in non-discrete groups. RAMJI LAL and R P SHUKLA. Department of Mathematics, University of Allahabad, Allahabad 211 002, India. E-mail: ramjilal@mri.ernet.in; rps@mri.ernet.in. MS received 2 August 2004; revised 4 August 2005. Abstract. The concept of 'topological right transversal' is introduced to study ...

  4. Neuropsychological intervention in kindergarten children with subtyped risks of reading retardation

    NARCIS (Netherlands)

    Glaude-Smit, S.W.D; van Strien, J.W.; Licht, R.; Bakker, D.J.

    2005-01-01

    Kindergarten children at risk of developing language problems were administered the Florida Kindergarten Screening Battery. A principal components analysis revealed a verbal and a visual-spatial component and subsequent discriminant function analyses a high verbal/low visual-spatial group (LAL:

  5. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 119; Issue 3. Issue front cover thumbnail. Volume 119, Issue 3. May 2007, pages 219-274. pp 219-230. Engineering macrocyclic figure-eight motif · V Haridas Harinder Singh Yogesh K Sharma Kashmiri Lal · More Details Abstract Fulltext PDF. The design and ...

  6. Feasibility of using a high power CO2 laser as an alternative source to test high heat load x-ray optics

    International Nuclear Information System (INIS)

    Fernandez, P.B.

    1993-01-01

    To determine the feasibility of using the CO 2 laser at LAL as an alternative heat source for x-ray optics tests, we have studied the absorption of the 10.6-micron laser light in silicon for two different dopant concentrations, using the resistivity as a predictor for the absorption length. We describe the results from these tests in this report

  7. Testing an hydrogen streamer chamber

    CERN Multimedia

    1975-01-01

    A 2x10 cm gap streamer chamber, 35x55 cm2 in surface, was built and tested at CERN. Good tracks of cosmic rays were obtained up to atmospheric pressure, see F. Rohrbach et al, CERN-LAL (Orsay) Collaboration, Nucl. Instr. Methods 141 (1977) 229. Michel Cathenoz stand on the center.

  8. The Importance of Fine-Scale Flow Processes and Food Availability in the Maintenance of Soft-Sediment Communities

    Science.gov (United States)

    1993-02-01

    the absence of the fauna, flora, and microbiota (Grant Lal. 1982). Furthermore, sediment "stability", in most cases, has not been defined using...attempting to do so, it may be more fruitful to develop new theories and models that embrace the gestalt of the sedimentary milieu. Returning to the

  9. SwissProt search result: AK107138 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK107138 002-124-C12 (P38571) Lysosomal acid lipase/cholesteryl ester hydrolase pre...cursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_HUMAN 4e-40 ...

  10. SwissProt search result: AK100511 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK100511 J023099N19 (P38571) Lysosomal acid lipase/cholesteryl ester hydrolase prec...ursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_HUMAN 2e-58 ...

  11. SwissProt search result: AK100511 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK100511 J023099N19 (Q64194) Lysosomal acid lipase/cholesteryl ester hydrolase prec...ursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_RAT 4e-51 ...

  12. SwissProt search result: AK064554 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK064554 002-112-C03 (P38571) Lysosomal acid lipase/cholesteryl ester hydrolase pre...cursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_HUMAN 6e-15 ...

  13. SwissProt search result: AK107138 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK107138 002-124-C12 (Q64194) Lysosomal acid lipase/cholesteryl ester hydrolase pre...cursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_RAT 7e-40 ...

  14. SwissProt search result: AK243532 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243532 J100077E15 (Q64194) Lysosomal acid lipase/cholesteryl ester hydrolase prec...ursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_RAT 2e-31 ...

  15. SwissProt search result: AK243532 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243532 J100077E15 (Q9Z0M5) Lysosomal acid lipase/cholesteryl ester hydrolase prec...ursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_MOUSE 6e-35 ...

  16. SwissProt search result: AK064554 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK064554 002-112-C03 (Q9Z0M5) Lysosomal acid lipase/cholesteryl ester hydrolase pre...cursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_MOUSE 6e-15 ...

  17. SwissProt search result: AK107138 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK107138 002-124-C12 (Q9Z0M5) Lysosomal acid lipase/cholesteryl ester hydrolase pre...cursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_MOUSE 2e-39 ...

  18. SwissProt search result: AK100511 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK100511 J023099N19 (Q9Z0M5) Lysosomal acid lipase/cholesteryl ester hydrolase prec...ursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_MOUSE 2e-52 ...

  19. SwissProt search result: AK064554 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK064554 002-112-C03 (Q64194) Lysosomal acid lipase/cholesteryl ester hydrolase pre...cursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_RAT 1e-11 ...

  20. SwissProt search result: AK243532 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243532 J100077E15 (P38571) Lysosomal acid lipase/cholesteryl ester hydrolase prec...ursor (EC 3.1.1.13) (LAL) (Acid cholesteryl ester hydrolase) (Sterol esterase) (Lipase A) (Cholesteryl esterase) LICH_HUMAN 9e-36 ...

  1. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 223-229 Special: Supersymmetric Unified Theories and Higgs Physics. Prospects of experimentally reachable beyond Standard Model physics in inverse see-saw motivated SO(10) GUT · Ram Lal Awasthi · More Details Abstract Fulltext PDF. The grand unification theories based on SO(10) gauge group have been at the ...

  2. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. S C Mishra. Articles written in Pramana – Journal of Physics. Volume 61 Issue 4 October 2003 pp 633-644 Research Articles. Second invariant for two-dimensional classical super systems · S C Mishra Roshan Lal Veena Mishra · More Details Abstract Fulltext PDF.

  3. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Mullite retains the usual orthorhombic habit of sillimanite. Rounded to sub rounded zirconia dispersed within the mullite matrix of the sample ZA is noticed. pp 221-225 Sol-gel Materials. Role of binder in the synthesis of titania membrane · K S Seshadri M Selvaraj R Kesava Moorthy K Varatharajan M P Srinivasan K B Lal.

  4. Un labo qui défie les lois de la physique

    CERN Multimedia

    Demarthon, Fabrice

    2006-01-01

    Preparation for action! The discoveries about particles don't stop to push aside theories of classic physics. Among the responsibles, a troop of physicists from LAL who track, measure and try to understand the world of infinitely small and the physics of tomorrow. (2 pages)

  5. Influence of crystal–melt interface shape on self-seeding and single ...

    Indian Academy of Sciences (India)

    Unknown

    Self-seeding; orientation; interface shape; antimonide crystals; VDS technique. 1. Introduction ... fundamental characteristics of source materials, various crystal growth models ... to the temperature 50°C above the melting temperature of the crystals ..... Gadkari D B, Lal K B, Shah A P and Arora B M 1997 J. Cryst. Growth 173 ...

  6. A Workshop in Transcultural Nursing.

    Science.gov (United States)

    Stevenson, Thomas B.

    1986-01-01

    Describes an experimental, week-long interdisciplinary (i.e., nursing and anthropology) workshop on the relationship between health and culture conducted by Ohio University, Zanesville, in conjunction with the University of Toronto. Discusses program formulation, objectives, results, and suggestions for future workshops. (LAL)

  7. Evaluation of antibody response in mice against avian influenza A

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 39; Issue 3. Evaluation of antibody response in mice against avian influenza A (H5N1) strain neuraminidase expressed in yeast Pichia pastoris. Murugan Subathra Ponsekaran Santhakumar Mangamoori Lakshmi Narasu Syed Sultan Beevi Sunil K Lal. Articles Volume 39 ...

  8. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    Elected: 1974 Section: Engineering & Technology. Lal, Prof. Shankar Ph.D. (CIT). Date of birth: 25 June 1923. Date of death: 25 September 1991. Specialization: Fluid Mechanics, Heat Transfer and Solid Mechanics Last known address: Dept. of Mechanical & Industrial, Engineering, University of Roorkee, Roorkee 247 667.

  9. Quantum mechanics of yr and non-yr-symmetric potentials in three ...

    Indian Academy of Sciences (India)

    Author Affiliations. BHARDWAJ S B1 2 SINGH RAM MEHAR1 MISHRA S C3. Department of Physics, Chaudhary Devi Lal University, Sirsa 125 055, India; Department of Applied Sciences, Chandigarh Engineering College, Landran, Mohali 140 307, India; Department of Physics, Kurukshetra University, Kurukshetra 136 ...

  10. Osmium and cobalt complexes incorporating facially coordinated N ...

    Indian Academy of Sciences (India)

    Administrator

    coordinated N,N,O donor azo-imine ligands: Redox and catalytic properties. Poulami Pattanayak, a. Debprasad Patra, a. Jahar Lal Pratihar, a. Andrew Burrows,. Mary F. Mahon b and Surajit Chattopadhyay* a a. Department of Chemistry, University of Kalyani, Kalyani-741235, India b. Department of Inorganic Chemistry, ...

  11. Analyzing Systems Integration Best Practices and Assessment in DoD Space Systems Acquisition

    Science.gov (United States)

    2009-12-01

    AFIT/GLM/LAL/93S-1, 1993. 2. Adoption of ISO /IEC 15288:2002 Systems Engineering – System Life Cycle Process. Institute of Electrical and Electronic...Air Force. 40. Pennel, L.W. and Knight, F.L (Eds). TOR-2005( 8583 )-3, Systems Engineering. The Aerospace Corporation, 2005. 41. Roche, James G

  12. Genetic selection for coping style predicts stressor susceptibility

    NARCIS (Netherlands)

    Veenema, AH; Meijer, OC; de Kloet, ER; Koolhaas, JM

    Genetically selected aggressive (SAL) and nonaggressive (LAL) male wild house-mice which show distinctly different coping styles, also display a differential regulation of the hypothalamic-pituitary-adrenal axis after exposure to an acute stressor. To test the hypothesis that coping style predicts

  13. Differences in the effects of 5-HT1A receptor agonists on forced swimming behavior and brain 5-HT metabolism between low and high aggressive mice

    NARCIS (Netherlands)

    Veenema, AH; Cremers, TIFH; Jongsma, ME; Steenbergen, PJ; de Boer, SF; Koolhaas, JM; Jongsma, Minke E.

    Rationale: Male wild house- mice genetically selected for long attack latency ( LAL) and short attack latency ( SAL) differ in structural and functional properties of postsynaptic serotonergic- 1A ( 5- HT1A) receptors. These mouse lines also show divergent behavioral responses in the forced swimming

  14. Differences in basal and stress-induced HPA regulation of wild house mice selected for high and low aggression

    NARCIS (Netherlands)

    Veenema, AH; Meijer, OC; de Kloet, ER; Koolhaas, JM; Bohus, BG; Meijer, Onno C.; Koolhaas, J M

    Male wild house mice, selected for short (SAL) and long (LAL) attack latency, show distinctly different behavioral strategies in coping with environmental challenges. In this study, we tested the hypothesis that this difference in coping style is associated with a differential stress responsiveness

  15. Lesao óssea em leucemias agudas linfoblásticas tipo T e TIPO nao T / nao B

    OpenAIRE

    Martins, Fernando Lopes

    2013-01-01

    Resumo: O AUTOR APRESENTA OS RESULTADOS DO ESTUDO RADIOLÓGICO DE ESQUELETO DE 61 PACIENTES PORTADORES DE LEUCEMIA AGUDA LINFOBLÁSTICA, CORRELACIONANDO A PRESENÇA OU NÃO DE Lesões ÓSSEAS COM A CLASSIFICAÇÃO IMUNOLÓGICA DE LAL TIPO T E TIPO não T / não B

  16. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 61; Issue 4. Volume 61, Issue 4. October 2003, pages 633-778 and C779-C783. pp 633-644 Research Articles. Second invariant for two-dimensional classical super systems · S C Mishra Roshan Lal Veena Mishra · More Details Abstract Fulltext PDF. Construction of ...

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Wide-angle X-ray scattering (WAXS) recordings were carried out on raw Dharwar cotton fibres available in Karnataka. Using this data and employing linked atom least squares (LALS) method, we report here the molecular and crystal structure of these cotton fibres. Employing structural data, we have computed elastic ...

  18. የታክስ ከፋዮች ቅሬታ Aፈታት ሥርዓት በIትዮጵያ

    African Journals Online (AJOL)

    Aschalew_A

    የታክስ ከፋዮች ቅሬታ Aፈታት በIትዮጵያ (Tax Appeal Procedures in Ethiopia) ..... Survey of African Economic Policy, Discussion Paper Number 3 July 1998, available ..... 55 B.B. Lal and N.Vashisht (2006), Direct Taxes: Income Tax,Wealth and Tax ...

  19. Research in the School of Languages and Linguistics at Griffith University

    Science.gov (United States)

    Fenton-Smith, Ben; Walkinshaw, Ian

    2014-01-01

    Griffith University is set across five campuses in south-east Queensland, Australia, and has a student population of 43,000. The School of Languages and Linguistics (LAL) offers programs in linguistics, international English, Chinese, Italian, Japanese and Spanish, as well as English language enhancement courses. Research strands reflect the…

  20. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-06

    Jan 6, 2016 ... Home; Journals; Pramana – Journal of Physics; Volume 86; Issue 2. Prospects of experimentally reachable beyond Standard Model physics in inverse see-saw motivated SO(10) GUT. Ram Lal Awasthi. Special: Supersymmetric Unified Theories and Higgs Physics Volume 86 Issue 2 February 2016 pp 223- ...

  1. Essential oil of Hexalobus monopetalus (A. Rich) Engl. leaves from Benin : a new source of citral

    NARCIS (Netherlands)

    Leclercq, P.A.; Ayedoun, M.A.; Sossou, P.V.; Houngnon, P.

    1997-01-01

    The leaf oil of Hexalobus monopetalus (Annonaceae) from Benin was analyzed by high resolution GC and GC/MS. Forty components were identified, representing more than 95% of the oiL The main constituents were geranial (37,9'lAl), neral (30,9%), linalool (35%), (E)-anethole (2.6%), selin-ll-en-4a-ol

  2. Endotoxin testing of proteins for parenteral administration using the Mono Mac 6 assay

    DEFF Research Database (Denmark)

    Moesby, Lise; Hansen, E W; Christensen, J D

    2000-01-01

    Pharmaceutical products containing proteins cause problems in testing for endotoxin and pyrogens. Many proteins interfere with the LAL test and the proteins are immunogenic in rabbits. The monocytic cell line Mono Mac 6 is an alternative assay for detection of endotoxin and other pyrogens....

  3. Language in the Workplace Project and Workplace Communication for Skilled Migrants Course at Victoria University of Wellington, New Zealand

    Science.gov (United States)

    de Bres, Julia; Holmes, Janet; Joe, Angela; Marra, Meredith; Newton, Jonathan; Riddiford Nicky; Vine, Bernadette

    2009-01-01

    The School of Linguistics and Applied Language Studies (LALS) at Victoria University of Wellington conducts research and teaching in Linguistics, Applied Linguistics, Writing and Deaf Studies. It incorporates a Deaf Studies Research Unit, which undertakes research on topics relating to deaf people and their language in New Zealand, and the New…

  4. Fulltext PDF

    Indian Academy of Sciences (India)

    Dictionary of Biology. Chancal Sarin. Toto McGraw Hill. 1996, Rs.90. Stoichiometry (51 Units). B I Bhatt and S M Vora. 3rd Edn., Toto McGraw Hill. 1996, Rs.180. Tensor Calculus, Theory and. Problems. A N Srivastava. Universities Press. 1994, Rs.50. A Textbook of Two Dimensional. Geometry. Sat Pal and Harbans lal.

  5. Monitoring soil erosion features using a time series of airborne remote sensing data: a case study Wild Coast, South Africa

    CSIR Research Space (South Africa)

    Singh, RG

    2014-10-01

    Full Text Available (accessed October 2013). Lal R. 2003. Soil erosion and the global carbon budget. Environment International, 29, pp. 437-450. Le Roux J. J., 2011. Monitoring soil erosion in South Africa at a regional scale. ISCW Report No. GW/A/2011/23. ARC...

  6. Occurrence of heavy rainfall around the confluence line in monsoon ...

    Indian Academy of Sciences (India)

    that when the disturbance-centre is away from the basin, heavy rainfall may also occur in the basin area close to ... Lal 1958; Bedekar and Benarjee 1969) extending .... 13. 26.8.1977. 23.3. D around C.L.. 14. 18.8.1978. 40.5. D around C.L.. 15.

  7. 78 FR 76112 - 36(b)(1) Arms Sales Notification

    Science.gov (United States)

    2013-12-16

    ... DEPARTMENT OF DEFENSE Office of the Secretary [Transmittal Nos. 13-63] 36(b)(1) Arms Sales... Department of Defense is publishing the unclassified text of a section 36(b)(1) arms sales notification. This... case LAJ-$22M--8Mar07 FMS case GAU-$45M--25Jul08 FMS case LAL-$293M--5Jan09 (vi) Sales Commission, Fee...

  8. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Astrophysics and Astronomy. Prateek Sharma. Articles written in Journal of Astrophysics and Astronomy. Volume 37 Issue 4 December 2016 pp 31 Review. Clusters of Galaxies and the Cosmic Web with Square Kilometre Array · Ruta Kale K. S. Dwarakanath Dharam Vir Lal Joydeep Bagchi ...

  9. Partial-Discharge Tests of Multiwinding High-Voltage Transformers for Space TWTAs (Traveling-Wave Tube Amplifiers).

    Science.gov (United States)

    1985-09-23

    34" .-* .V° --. 𔄁° "’" . y-. " .,- .r- ..-- . ru-. . La.L 4.’. C’... o 0 0 I,-- E - o Q0 Ldhi z0 LA-, =E ;’-’. -0 L.C AA. r- 0"" 7-- ., I-:. ILI.’ I I I

  10. Toward an animal model for antisocial behavior : parallels between mice and humans

    NARCIS (Netherlands)

    Sluyter, F; Arseneault, L; Moffitt, TE; Veenema, AH; de Boer, S; Koolhaas, JM

    The goal of this article is to examine whether mouse lines genetically selected for short and long attack latencies are good animal models for antisocial behavior in humans. To this end, we compared male Short and Long Attack Latency mice (SAL and LAL, respectively) with the extremes of the Dunedin

  11. Deregulation: Implications for Community College Leaders.

    Science.gov (United States)

    Bender, Louis W.

    1986-01-01

    Looks at the ways in which the deregulation of business and industry may affect community colleges in the years ahead, using the banking industry as an illustration. Argues that the deregulation of higher education requires that community college leadership programs examine past assumptions and develop new strategies. (LAL)

  12. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Astrophysics and Astronomy. Viral Parekh. Articles written in Journal of Astrophysics and Astronomy. Volume 37 Issue 4 December 2016 pp 31 Review. Clusters of Galaxies and the Cosmic Web with Square Kilometre Array · Ruta Kale K. S. Dwarakanath Dharam Vir Lal Joydeep Bagchi Surajit ...

  13. Behavioral profiles of genetically selected aggressive and nonaggressive male wild house mice in two anxiety tests

    NARCIS (Netherlands)

    Hogg, S; Wurbel, H; Steimer, T; de Ruiter, A; Koolhaas, J; Sluyter, F; Driscoll, Peter

    2000-01-01

    Artificially selected aggressive (SAL) and non-aggressive (LAL) male house mice were tested in a hexagonal tunnel maze and light-dark preference (LD) box to determine if the bidirectional selection for aggressive behavior leads to a coselection for different levels of trait anxiety. The tunnel maze

  14. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    Kapur, Prof. Ravinder Lal Ph.D. (Edinburgh).,., FRC Psych. Date of birth: 7 July 1938. Date of death: 24 November 2006. Specialization: Psychiatry, Psychiatric Epidemiology and Yoga Last known address: Emeritus Professor, National Institute of Advanced Studies, Indian Institute of Science Campus, Bengaluru 560 012.

  15. Tanzania Journal of Agricultural Sciences - Vol 14, No 1 (2015)

    African Journals Online (AJOL)

    Agricultural drought analysis for sustainable smallholder maize production in semi-arid areas: a case study of the Lower Moshi Irrigation Scheme, Tanzania · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Patrick Bell, Didas Kimaro, Rattan Lal ...

  16. Molecular and clinical characterization of a series of patients with childhood-onset lysosomal acid lipase deficiency. Retrospective investigations, follow-up and detection of two novel LIPA pathogenic variants.

    Science.gov (United States)

    Pisciotta, Livia; Tozzi, Giulia; Travaglini, Lorena; Taurisano, Roberta; Lucchi, Tiziano; Indolfi, Giuseppe; Papadia, Francesco; Di Rocco, Maja; D'Antiga, Lorenzo; Crock, Patricia; Vora, Komal; Nightingale, Scott; Michelakakis, Helen; Garoufi, Anastasia; Lykopoulou, Lilia; Bertolini, Stefano; Calandra, Sebastiano

    2017-10-01

    Childhood/Adult-onset Lysosomal Acid Lipase Deficiency (LAL-D) is a recessive disorder due to loss of function variants of LAL, the enzyme which hydrolyses cholesteryl esters, derived from internalized apoB containing lipoproteins. The disease is characterized by multi-organ involvement including the liver, spleen, intestine and cardiovascular system. The aim of this study was the clinical and molecular characterization of 14 (13 unrelated) previously unreported patients with childhood-onset LAL-D. Data collected included clinical and laboratory investigations, liver imaging, liver biopsy and LIPA gene analysis. The response to lipid-lowering medications, liver transplantation and enzyme replacement therapy (ERT) was reported for some patients. LAL-D was suspected at 4.4 ± 3.3 years of age for the presence of hepatomegaly, elevated serum transaminases and hypercholesterolemia, and was confirmed by liver biopsy/imaging and LAL assay. The follow up period ranged from 3 to 40 years (mean 7.8 ± 4.0 years in 13 cases). Patients treated with statins with or without ezetimibe showed 28% reduction of plasma LDL-cholesterol without a tangible effect on liver enzymes; some patients receiving ERT showed normalized lipoprotein profile and transaminase levels. The common c.894G > A variant was observed in homozygosity or compound heterozygosity in 10 patients. We found seven previously reported variants: p.(Trp140*), p.(Arg218*), p.(Gly266*), p.(Thr288Ile), p.(Leu294Ser), p.(His295Tyr) and p.(Gly342Arg) and two novel variants: p.(Asp345Asn), affecting the LAL catalytic triad, and c.229+3A > C, affecting splicing. Homozygosity for p.(Thr288Ile) or c.229+3A > C was associated with a severe phenotype. This study provides additional data on the features of childhood-onset LAL-D and describes two novel pathogenic variants of the LIPA gene. Copyright © 2017. Published by Elsevier B.V.

  17. Determination of bacterial endotoxin (pyrogen) in radiopharmaceuticals by the gel clot method. Validation

    International Nuclear Information System (INIS)

    Fukumori, Neuza Taeko Okasaki

    2008-01-01

    Before the Limulus amebocyte lysate (LAL) test, the only available means of pirogenicity testing for parenteral drugs and medical devices was the United States Pharmacopoeia (USP) rabbit pyrogen test. Especially for radiopharmaceuticals, the LAL assay is the elective way to determine bacterial endotoxin. The aim of this work was to validate the gel clot method for some radiopharmaceuticals without measurable interference. The FDA's LALTest guideline defines interference as a condition that causes a significant difference between the endpoints of a positive water control and positive product control series using a standard endotoxin. Experiments were performed in accordance to the USP bacterial endotoxins test in the 131 I- m-iodobenzylguanidine; the radioisotopes Gallium-67 and Thallium-201; the lyophilized reagents DTPA, Phytate, GHA, HSA and Colloidal Tin. The Maximum Valid Dilution (MVD) was calculated for each product based upon the clinical dose of the material and a twofold serial dilution below the MVD was performed in duplicate to detect interferences. The labeled sensitivity of the used LAL reagent was 0.125 EU mL -1 (Endotoxin Units per milliliter). For validation, a dilution series was performed, a twofold dilution of control standard endotoxin (CSE) from 0.5 to 0.03 EU mL -1 , to confirm the labeled sensitivity of the LAL reagent being tested in sterile and non pyrogenic water, in quadruplicate. The same dilution series was performed with the CSE and the product in the 1:100 dilution factor, in three consecutive batches of each radiopharmaceutical. The products 131 I-m-iodobenzylguanidine, Gallium-67, Thallium-201, DTPA, HSA and Colloidal Tin were found compatible with the LAL test at a 1:100 dilution factor. Phytate and GHA showed some interference in the gel clot test. Other techniques to determine endotoxins as the chromogenic (color development) and the turbidimetric test (turbidity development), were also assessed to get valuable quantitative and

  18. Determination of bacterial endotoxin (pyrogen) in radiopharmaceuticals by the gel clot method. Validation; Determinacao de endotoxina bacteriana (pirogenio) em radiofarmacos pelo metodo de formacao de gel. Validacao

    Energy Technology Data Exchange (ETDEWEB)

    Fukumori, Neuza Taeko Okasaki

    2008-07-01

    Before the Limulus amebocyte lysate (LAL) test, the only available means of pirogenicity testing for parenteral drugs and medical devices was the United States Pharmacopoeia (USP) rabbit pyrogen test. Especially for radiopharmaceuticals, the LAL assay is the elective way to determine bacterial endotoxin. The aim of this work was to validate the gel clot method for some radiopharmaceuticals without measurable interference. The FDA's LALTest guideline defines interference as a condition that causes a significant difference between the endpoints of a positive water control and positive product control series using a standard endotoxin. Experiments were performed in accordance to the USP bacterial endotoxins test in the {sup 131}I- m-iodobenzylguanidine; the radioisotopes Gallium-67 and Thallium-201; the lyophilized reagents DTPA, Phytate, GHA, HSA and Colloidal Tin. The Maximum Valid Dilution (MVD) was calculated for each product based upon the clinical dose of the material and a twofold serial dilution below the MVD was performed in duplicate to detect interferences. The labeled sensitivity of the used LAL reagent was 0.125 EU mL{sup -1} (Endotoxin Units per milliliter). For validation, a dilution series was performed, a twofold dilution of control standard endotoxin (CSE) from 0.5 to 0.03 EU mL{sup -1}, to confirm the labeled sensitivity of the LAL reagent being tested in sterile and non pyrogenic water, in quadruplicate. The same dilution series was performed with the CSE and the product in the 1:100 dilution factor, in three consecutive batches of each radiopharmaceutical. The products {sup 131}I-m-iodobenzylguanidine, Gallium-67, Thallium-201, DTPA, HSA and Colloidal Tin were found compatible with the LAL test at a 1:100 dilution factor. Phytate and GHA showed some interference in the gel clot test. Other techniques to determine endotoxins as the chromogenic (color development) and the turbidimetric test (turbidity development), were also assessed to get valuable

  19. Educational philosophy in China:a centennial retrospect and prospect

    Institute of Scientific and Technical Information of China (English)

    LU Youquan; CHI Yanjie

    2007-01-01

    Educational philosophy in China during the 20th century started with the introduction of John Dewey's educational philosophy thoughts,followed by the dissemination of Marxism thoughts of education,and initially established the framework of educational philosophy as an academic discipline.After the foundation of the People's Republic of China in 1949,especially during the 1980s,under the guidance of Marxism,the discipline of educational philosophy has been maturing.While exploring China's history of educational philosophy,this article also covers contemporary Western development.Future trends of this discipline include extending specific fields of research,increasing internationalization of research,enhancing the functions of both critique and guiding ideals of educational philosophy.

  20. Síntese e Caracterização Estrutural de Complexos Metálicos de Cu(II para Modificação de Eletrodo de Carbono Vítreo por Adsorção Química

    Directory of Open Access Journals (Sweden)

    Iulle Costa Sanchez

    2016-04-01

    Full Text Available The copper complexes has been synthesized resulting in a yield of 90%. The melting point of the complex and UV-Vis spectroscopy suggested complexation with high purity. The atomic absorption spectroscopy flame determined, together with the gravimetric analysis, the stoichiometric ratio obtained between metal and ligand for the complex. The potentiometric titration proposed which active sites are related to coordination with the metal, such coordination’s sites were confirmed by infrared spectroscopy. Studies about the adsorption of chemical modifiers in the glassy carbon of the electrode surface resulting in obtaining ideal conditions for the electrode modification estimating the exact time of contact with modifier sunder ultrasound in different means of dissolution. The electrochemical properties of the electrodes howed improvements in electrochemical response to the redox couple Fe3-/4- than the unmodified electrode through organic dissolution. DOI: http://dx.doi.org/10.17807/orbital.v8i2.807

  1. Reviewer Database

    Directory of Open Access Journals (Sweden)

    Chief Editor

    2016-06-01

    RRachit NegiRadhika MariappanRafiq MirRahul BansalRahul ChaturvediRahul DandekarRahul KatiyarRaihan BoyleRaja JebasinghRajarajan KRajeev BijalwanRajesh GaikwadRajesh GargRajesh KumarRajesh KunwarRajinder SamyalRaju PatilRakesh KakkarRakesh SharmaRam MandalRama SinghR KamathRanganatha S CRanjana SinghRanjeeta KumariRapolu YadagiriRashmi GodeRashmi HullalliRavi AvRavi ShankarRavikiran KamateRavleen BakshiReema KumariReetu SharmaRenu AgarwalRenu ChauhanRenu SulakheRicha SinhaRijul RanjanRijuta PandavRitika TiwariRitu KashyapRochak SaxenaRohit DhakaRuby KhanRuchi DharRuchi JuyalRuchir RustagiRuchita DixitRujul ShuklaRujuta HadayeRupali RoyS C GuptaS D KandpalS MohapatraS SaxenaSachin GuptaSachin PandeySachin YadavSadhana AwasthiJyoti SharmaSaima AkhundSamarjeet KaurSamreen KhanS ChakrabortySandeep BabarSandeep PanigrahiSandip KumarSanjay GuptaSanjay JhaSanjay PandeySanjay TripathiSanjay ZodpeySanjeev DaveySanjeev GuptaSanjeev KhichiSanjeev KumarS VaithiyalingamSarita SoodSatya LenkaS ChakrabortyS VarshneySayani DuttaSayed K MominSeema DiwanSeema JainSenthil Kumar S KShabnam AnsariShailendra KumarShailesh KawaleShailesh SumanShaili VyasShalini DwivediPooransinghShalini SrivastavShanta KhesSharvanan UdayarShashank K JShazia ShafiSheesham AgarwalSheetal PatelSheikh SaleemShereen SadiqShibani DattaShikha HandaShivani KalraShivani RaoShivender SinghShivraj BhimteShraddha MishraShveta SainiShweta RajpalShyam DixitS ShivalliS MukherjeeSimmi OberoiSindhuri RSitanshu KarSmiji ChiramalSmita ValekarSonal RaniSonali ChoudhariSonia TiwariSonu GoelSrikanth ReddyS RanganathanS Krishnan VSrishti DixitSubodh KarmakarSudharshini SubramaniamSudhir ChawlaSudhir GuptaS BhattacharyaSugandha JauhariSujan MarahattaSumana SamantaSumeet DixitSumit DhruveSumit JethaniSunder LalSuneel KaushalSunil GargSunil MisraSunita DhakedSunny AggarwalSuprakas HazraSurabhi MishraSuraj ChawlaSuraj SenjamSuravi PatraSurekha KishoreS TripathiSurya BaliSushil BansalSushil DalalSushil KabraSushil ShuklaSwapan Maji

  2. ATLAS endcap liquid argon calorimeters. Description and construction of the cryostats

    Energy Technology Data Exchange (ETDEWEB)

    Mace, Guy; Prat, Serge; Veillet, Jean-Jacques [Laboratoire de l' Accelerateur Lineaire IN2P3-CNRS et Universite de Paris-Sud 11, BP 34, F-91898 Orsay Cedex (France)

    2006-05-15

    All forward calorimeters of the ATLAS detector use the same detection technique, energy loss in passive plates, followed by ionisation and charge detection in liquid argon. They are therefore all grouped in the same vessel which must basically support and keep in place the heavy plates and the detection electrodes and maintain liquid argon at cold and stable temperature. Taking into account all the constraints as detailed below, and the overall detector size, 5 meter diameter by 3 meter length this was quite a challenge. The design, construction and tests of these two cryostats, up to their delivery at CERN, are described in this document. These two cryostats are a joint 'in kind' contribution to the Atlas experiment of LAL (Orsay), Max Planck Institute (Muenchen) and Wuppertal University (Wuppertal) and have been designed and built under the responsibility of LAL (Orsay) with contributions of the technical groups of the above institutions and of ATLAS-CERN. (authors)

  3. Validation of cosmogenic nuclide production rate scaling factors through direct measurement

    Energy Technology Data Exchange (ETDEWEB)

    Graham, I.J. E-mail: i.graham@gns.cri.nz; Barry, B.J.; Ditchburn, R.G.; Whitehead, N.E

    2000-10-01

    {sup 7}Be produced in water targets by nuclear interactions of cosmic rays has been measured to determine cosmogenic nuclide production rates as a function of altitude (sea level to 2 km) and geomagnetic latitude (20-79 deg. S). Relative intensities of low energy cosmic ray neutrons have at the same time been measured using neutron monitors based on IGY/NM-64 designed to efficiently thermalise ca. 2-30 MeV neutrons. The research is on-going and we present here preliminary data from the past two years. Water target and neutron flux results are in general agreement, and are consistent with the altitude-dependent scaling factors of Lal [Earth Planet. Sci. Lett. 104 (1991) 4241]. Significant differences between the sea level, latitude-dependent neutron flux data and Lal's predictions are possibly related to the response function of the detector.

  4. Validation of cosmogenic nuclide production rate scaling factors through direct measurement

    CERN Document Server

    Graham, I J; Ditchburn, R G; Whitehead, N E

    2000-01-01

    sup 7 Be produced in water targets by nuclear interactions of cosmic rays has been measured to determine cosmogenic nuclide production rates as a function of altitude (sea level to 2 km) and geomagnetic latitude (20-79 deg. S). Relative intensities of low energy cosmic ray neutrons have at the same time been measured using neutron monitors based on IGY/NM-64 designed to efficiently thermalise ca. 2-30 MeV neutrons. The research is on-going and we present here preliminary data from the past two years. Water target and neutron flux results are in general agreement, and are consistent with the altitude-dependent scaling factors of Lal [Earth Planet. Sci. Lett. 104 (1991) 4241]. Significant differences between the sea level, latitude-dependent neutron flux data and Lal's predictions are possibly related to the response function of the detector.

  5. The neurobiological basis of orientation in insects: insights from the silkmoth mating dance.

    Science.gov (United States)

    Namiki, Shigehiro; Kanzaki, Ryohei

    2016-06-01

    Counterturning is a common movement pattern during orientation behavior in insects. Once male moths sense sex pheromones and then lose the input, they demonstrate zigzag movements, alternating between left and right turns, to increase the probability to contact with the pheromone plume. We summarize the anatomy and function of the neural circuit involved in pheromone orientation in the silkmoth. A neural circuit, the lateral accessory lobe (LAL), serves a role as the circuit module for zigzag movements and controls this operation using a flip-flop neural switch. Circuit design of the LAL is well conserved across species. We hypothesize that this zigzag module is utilized in a wide range of insect behavior. We introduce two examples of the potential use: orientation flight and the waggle dance in bees. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Estimativa da incerteza em ensaio de detecção de endotoxina bacteriana pelo método de gelificação Estimation of uncertainty in the detection of bacterial endotoxin by gel-clot method

    Directory of Open Access Journals (Sweden)

    Felipe Rebello Lourenço

    2005-12-01

    Full Text Available Desde a publicação da ISO 17025:1999, o interesse em métodos para estimativa da incerteza em ensaios qualitativos, do tipo "passa/não passa", têm ganho grande importância. Uma forma de estimar e informar a incerteza deste tipo de ensaio é o uso das probabilidades de respostas-falsas, particularmente falsos-positivos e falsos-negativos, determinados a partir do teorema de Bayes. O objetivo deste artigo é estabelecer um método para a estimativa de incerteza em ensaios de detecção de endotoxina bacteriana pelo método in vitro Limulus Amebocyte Lysate (LAL. Considerando a confirmação da sensibilidade do LAL e a validação do teste, a probabilidade de uma resposta falsa corresponde à soma da probabilidade dos resultados falso-negativos e falso-positivos. A partir dos resultados obtidos foi verificado que a etapa da confirmação da sensibilidade do LAL contribui para a incerteza de forma mais significativa (67,6% que a etapa de validação do teste (32,4%. Através de um procedimento simples, descrito neste artigo, e de dados obtidos a partir da confirmação da sensibilidade do LAL e validação do teste para um produto em questão é possível obter uma estimativa de incerteza razoável para o ensaio de detecção de endotoxinas bacterianas pelo método de gelificação.Since the publication of ISO 17025:1999, the interest in methods for estimation of the uncertainty in qualitative analysis, such as 'pass/fail', have became more important. The usual form of estimating and informing the uncertainty in this kind of analysis is the use of false-response rates, particularly false-positive and false-negative, determinated from Bayes theorem. The aim of this paper is establish a method for estimation of the uncertainty in the detection of bacterial endotoxins by in vitro Limulus Amebocyte Lysate (LAL test. Considering the confirmation of LAL sensitivity and the validation of the test, the probability of a false-response corresponds to the

  7. Optimization of HIP bonding conditions for ITER shielding blanket/first wall made from austenitic stainless steel and dispersion strengthened copper alloy

    International Nuclear Information System (INIS)

    Sato, S.; Hatano, T.; Kuroda, T.; Furuya, K.; Hara, S.; Enoeda, M.; Takatsu, H.

    1998-01-01

    Optimum bonding conditions were studied on the hot isostatic pressing (HIP) bonded joints of type 316L austenitic stainless steel and dispersion strengthened copper alloy (DSCu) for application to the ITER shielding blanket / first wall. HIP bonded joints were fabricated at temperatures in a 980-1050 C range, and a series of mechanical tests and metallurgical observations were conducted on the joints. Also, bondability of two grades of DSCu (Glidcop Al-25 trademark and Al-15 trademark ) with SS316L was examined in terms of mechanical properties of the HIP bonded joints. From those studies it was concluded that the HIP temperature of 1050 C was an optimal condition for obtaining higher ductility, impact values and fatigue strength. Also, SS316L/Al-15 joints showed better results in terms of ductility and impact values compared with SS316L/Al-25 joints. (orig.)

  8. ATLAS endcap liquid argon calorimeters. Description and construction of the cryostats

    International Nuclear Information System (INIS)

    Mace, Guy; Prat, Serge; Veillet, Jean-Jacques

    2006-05-01

    All forward calorimeters of the ATLAS detector use the same detection technique, energy loss in passive plates, followed by ionisation and charge detection in liquid argon. They are therefore all grouped in the same vessel which must basically support and keep in place the heavy plates and the detection electrodes and maintain liquid argon at cold and stable temperature. Taking into account all the constraints as detailed below, and the overall detector size, 5 meter diameter by 3 meter length this was quite a challenge. The design, construction and tests of these two cryostats, up to their delivery at CERN, are described in this document. These two cryostats are a joint 'in kind' contribution to the Atlas experiment of LAL (Orsay), Max Planck Institute (Muenchen) and Wuppertal University (Wuppertal) and have been designed and built under the responsibility of LAL (Orsay) with contributions of the technical groups of the above institutions and of ATLAS-CERN. (authors)

  9. Visión táctil: una forma de reconocimiento espacial mediante estimulación táctil pasiva en sujetos invidentes

    OpenAIRE

    Soria Claros, Angélica Millie

    2016-01-01

    Hay estudios que sostienen que el reconocimiento de lal información de todos los sentidos , y entre ellos la visión, se da en el cerebro y no solo en los ojos, el cual , opta por realizar asociaciones de forma muy rápida entre los estímulos que le llegar y la información que ya tiene almacenada en la memoria a corto plazo...

  10. THE EVALUATION OF SOIL EROSION OFF-SITES EFFECTS IN LARGE BASINS: THE STUDYCASE OF LERMA-CHAPALA WATERSHED, MEXICO

    OpenAIRE

    Helena Cotler A.; Susana Gutierrez D.; Carlos Enriquez G.; Arturo Garrido P.

    2005-01-01

    One of the primary global concerns during the new millennium is the assessment of the impact of accelerated soil erosion on the economy and the environment (Pimentel et al. 1995; Lal, 1995). Erosion damages the site on which it occurs and also has undesirable effects off-site in the larger environment. Erosion moves sediments and nutrients out of the land, creating the two most widespread water pollution problems in the rivers, lakes and dams. The nutrients impact water quality largely throug...

  11. OMEGAPIX 3D integrated circuit prototype dedicated to the ATLAS upgrade Super LHC pixel project

    CERN Document Server

    Thienpont, D; de La Taille, C; Seguin-Moreau, N; Martin-Chassard, G; Guo b, Y

    2009-01-01

    In late 2008, an international consortium for development of vertically integrated (3D) readout electronics was created to explore features available from this technology. In this paper, the OMEGAPIX circuit is presented. It is the first front-end ASIC prototype designed at LAL in 3D technology. It has been submitted on May 2009. At first, a short reminder of 3D technology is presented. Then the IC design is explained: analogue tier, digital tier and testability.

  12. L-alanine distribution in the growth pyramids of TGS crystals and its influence on the growth, switching and domain structure

    International Nuclear Information System (INIS)

    Brezina, B.; Havrankova, M.

    1985-01-01

    The full-faced crystals of triglycine sulphate (TGS) and deuterated homologs substituted by L-alanine (LATGS and LADTGS, resp.) were grown from growth solutions with various concentrations of the substituent. The distribution of L, alanine (L,al) in various growth pyramids of crystals was measured by the electrical switching method. The stability of domain structure of doped crystals was studied by the liquid crystal method. (author)

  13. Healthcare resource use and costs of managing children and adults with lysosomal acid lipase deficiency at a tertiary referral centre in the United Kingdom.

    Directory of Open Access Journals (Sweden)

    Julian F Guest

    Full Text Available To estimate clinical progression and resource utilisation together with the associated costs of managing children and adults with LAL Deficiency, at a tertiary referral centre in the UK.A retrospective chart review was undertaken of patients in the UK with a confirmed diagnosis of LAL Deficiency who were managed at a LAL Deficiency tertiary referral treatment centre. Patients' pathways, treatment patterns, health outcomes and resource use were quantified over differing lengths of time for each patient enabling the NHS cost of patient management in tertiary care to be estimated.The study population comprised 19 patients of whom 58% were male. Mean age at the time of initial presentation was 15.5 years and the mean age at diagnosis was 18.0 years. 63%, 53% and 42% of patients had hepatomegaly, abnormal lipid storage and splenomegaly at a mean age of presentation of 17.8, 17.1 and 20.9 years, respectively. Over a period of 50 years there were a mean of 48.5 clinician visits and 3.4 hospital admissions per patient. The mean NHS cost of patient management at a LAL Deficiency tertiary referral treatment centre, spanning a period of over 50 years was £61,454 per patient.This study provides important insights into a number of aspects of the disease that are difficult to ascertain from published case reports. Additionally, it provides the best estimate available of NHS resource use and costs with which to inform policy and budgetary decisions pertaining to managing this ultra-orphan disease.

  14. Healthcare resource use and costs of managing children and adults with lysosomal acid lipase deficiency at a tertiary referral centre in the United Kingdom.

    Science.gov (United States)

    Guest, Julian F; Ingram, Andy; Ayoub, Nadia; Hendriksz, Christian J; Murphy, Elaine; Rahman, Yusof; McKiernan, Patrick; Mundy, Helen; Deegan, Patrick

    2018-01-01

    To estimate clinical progression and resource utilisation together with the associated costs of managing children and adults with LAL Deficiency, at a tertiary referral centre in the UK. A retrospective chart review was undertaken of patients in the UK with a confirmed diagnosis of LAL Deficiency who were managed at a LAL Deficiency tertiary referral treatment centre. Patients' pathways, treatment patterns, health outcomes and resource use were quantified over differing lengths of time for each patient enabling the NHS cost of patient management in tertiary care to be estimated. The study population comprised 19 patients of whom 58% were male. Mean age at the time of initial presentation was 15.5 years and the mean age at diagnosis was 18.0 years. 63%, 53% and 42% of patients had hepatomegaly, abnormal lipid storage and splenomegaly at a mean age of presentation of 17.8, 17.1 and 20.9 years, respectively. Over a period of 50 years there were a mean of 48.5 clinician visits and 3.4 hospital admissions per patient. The mean NHS cost of patient management at a LAL Deficiency tertiary referral treatment centre, spanning a period of over 50 years was £61,454 per patient. This study provides important insights into a number of aspects of the disease that are difficult to ascertain from published case reports. Additionally, it provides the best estimate available of NHS resource use and costs with which to inform policy and budgetary decisions pertaining to managing this ultra-orphan disease.

  15. Better differential diagnosis of iron deficiency anemia from beta-thalassemia trait

    Directory of Open Access Journals (Sweden)

    Fakher Rahim

    2009-09-01

    Full Text Available Objective: Iron deficiency anemia (IDA and beta-thalassemia trait (ß-TT are the most common forms of microcytic anemia. This study was conducted to compare the validity of various discrimination indices in differentiating β-TT from IDA by calculating their sensitivity, specificity and Youden's index.Methods: Totally 323 subjects (173 children and 150 adults with microcytic anemia were involved in this study. We calculated 10 discrimination indices in all patients with IDA and β-TT. We divided the patients into two different groups as younger or older than 10 years. Results: None of the indices showed sensitivity and specificity of 100% in the patients older than 10 years, and in the patients younger than 10 years, only Shine & Lal index showed sensitivity close to 90% and specificity of 100%. The most accurate discriminative index for patients younger than 10 years was Shine & Lal and for those older than 10 years it was RDW index. According to Youden's index, Shine & Lal and RBC count showed the greatest diagnostic value in patients younger than 10 years and RDW and RBC count indices in those older than 10 years. Conclusion: None of the indices was completely sensitive and specific in differentiation between β-TT and IDA. Mean and median mean cell Hb density (MCHD were very close to normal values in both IDA and β-TT patients, but in the case of mean density of Hb/liter (MDHL, we found that the mean and median were significantly higher than normal values in β-TT and lower than normal values in IDA patients. In our study, Youden's index of RBC and Shine & Lal were the highest and most reliable indices in differentiating β-TT from IDA in the patients younger than 10 years. For patients older than 10 years, the most reliable discrimination indices were RBC and RDW.

  16. Uncoordinated MAC for Adaptive Multi-Beam Directional Networks: Analysis and Evaluation

    Science.gov (United States)

    2016-04-10

    omni-directional and cannot support the desired data rates, number of nodes, or the necessary communications ranges to support emerging applications ...cations: IS-95 and third generation CDMA applications . Prentice Hall PTR, 1999. [3] V. Jain, A. Gupta, and D. P. Agrawal, “On-demand medium access in...of medium access control for wlans with multi-beam access point,” IEEE Trans. Wireless Commun., vol. 6, no. 2, pp. 556–565, 2007. [18] D. Lal, V

  17. Karyotype Evolution in Birds: from Conventional Staining to Chromosome Painting

    OpenAIRE

    Ferguson-Smith, Malcolm

    2018-01-01

    In this work we performed comparative chromosome painting using probes from Gallus gallus (GGA) Linnaeus, 1758 and Leucopternis albicollis (LAL) Latham, 1790 in Synallaxis frontalis Pelzeln, 1859 (Passeriformes, Furnariidae), an exclusively Neotropical species, in order to analyze whether the complex pattern of intrachromosomal rearrangements (paracentric and pericentric inversions) proposed for Oscines and Suboscines is shared with more basal species. S. frontalis has 82 chromosomes, similar...

  18. Sequence-based comparative study of classical swine fever virus genogroup 2.2 isolate with pestivirus reference strains.

    Science.gov (United States)

    Kumar, Ravi; Rajak, Kaushal Kishor; Chandra, Tribhuwan; Muthuchelvan, Dhanavelu; Saxena, Arpit; Chaudhary, Dheeraj; Kumar, Ajay; Pandey, Awadh Bihari

    2015-09-01

    This study was undertaken with the aim to compare and establish the genetic relatedness between classical swine fever virus (CSFV) genogroup 2.2 isolate and pestivirus reference strains. The available complete genome sequences of CSFV/IND/UK/LAL-290 strain and other pestivirus reference strains were retrieved from GenBank. The complete genome sequence, complete open reading frame, 5' and 3' non-coding region (NCR) sequences were analyzed and compared with reference pestiviruses strains. Clustal W model in MegAlign program of Lasergene 6.0 software was used for analysis of genetic heterogeneity. Phylogenetic analysis was carried out using MEGA 6.06 software package. The complete genome sequence alignment of CSFV/IND/UK/LAL-290 isolate and reference pestivirus strains showed 58.9-72% identities at the nucleotide level and 50.3-76.9% at amino acid level. Sequence homology of 5' and 3' NCRs was found to be 64.1-82.3% and 22.9-71.4%, respectively. In phylogenetic analysis, overall tree topology was found similar irrespective of sequences used in this study; however, whole genome phylogeny of pestivirus formed two main clusters, which further distinguished into the monophyletic clade of each pestivirus species. CSFV/IND/UK/LAL-290 isolate placed with the CSFV Eystrup strain in the same clade with close proximity to border disease virus and Aydin strains. CSFV/IND/UK/LAL-290 exhibited the analogous genomic organization to those of all reference pestivirus strains. Based on sequence identity and phylogenetic analysis, the isolate showed close homology to Aydin/04-TR virus and distantly related to Bungowannah virus.

  19. El vínculo infancia-televisión en la sociedad actual. Análisis de la programación televisiva infantil española

    OpenAIRE

    García Vega, Rodrigo; Torres Martín, César

    2009-01-01

    Si tenemos en cuenta que fundamentalmente en la población infantil los contenidos televisivos violentos aumentan su agresividad, que cuantas más horas viendo la televisión más disminuyen las ganas por la actividad física, o que tres o cuatro horas

  20. A novel reduction approach to fabricate quantum-sized SnO₂-conjugated reduced graphene oxide nanocomposites as non-enzymatic glucose sensors.

    Science.gov (United States)

    Ye, Yixing; Wang, Panpan; Dai, Enmei; Liu, Jun; Tian, Zhenfei; Liang, Changhao; Shao, Guosheng

    2014-05-21

    Quantum-sized SnO2 nanocrystals can be well dispersed on reduced graphene oxide (rGO) nanosheets through a convenient one-pot in situ reduction route without using any other chemical reagent or source. Highly reactive metastable tin oxide (SnO(x)) nanoparticles (NPs) were used as reducing agents and composite precursors derived by the laser ablation in liquid (LAL) technique. Moreover, the growth and phase transition of LAL-induced SnO(x) NPs and graphene oxide (GO) were examined by optical absorption, X-ray diffraction, X-ray photoelectron spectroscopy, Raman spectroscopy and high-resolution transmission electron microscopy. Highly dispersed SnO(x) NPs can also prevent rGO from being restacked into a multilayer structure during GO reduction. Given the good electron transfer ability and unsaturated dangling bonds of rGO, as well as the ample electrocatalytic active sites of quantum-sized SnO2 NPs on unfolded rGO sheets, the fabricated SnO2-rGO nanocomposite exhibited excellent performance in the non-enzymatic electrochemical detection of glucose molecules. The use of LAL-induced reactive NPs for in situ GO reduction is also expected to be a universal and environmentally friendly approach for the formation of various rGO-based nanocomposites.

  1. Microglomerular Synaptic Complexes in the Sky-Compass Network of the Honeybee Connect Parallel Pathways from the Anterior Optic Tubercle to the Central Complex.

    Science.gov (United States)

    Held, Martina; Berz, Annuska; Hensgen, Ronja; Muenz, Thomas S; Scholl, Christina; Rössler, Wolfgang; Homberg, Uwe; Pfeiffer, Keram

    2016-01-01

    While the ability of honeybees to navigate relying on sky-compass information has been investigated in a large number of behavioral studies, the underlying neuronal system has so far received less attention. The sky-compass pathway has recently been described from its input region, the dorsal rim area (DRA) of the compound eye, to the anterior optic tubercle (AOTU). The aim of this study is to reveal the connection from the AOTU to the central complex (CX). For this purpose, we investigated the anatomy of large microglomerular synaptic complexes in the medial and lateral bulbs (MBUs/LBUs) of the lateral complex (LX). The synaptic complexes are formed by tubercle-lateral accessory lobe neuron 1 (TuLAL1) neurons of the AOTU and GABAergic tangential neurons of the central body's (CB) lower division (TL neurons). Both TuLAL1 and TL neurons strongly resemble neurons forming these complexes in other insect species. We further investigated the ultrastructure of these synaptic complexes using transmission electron microscopy. We found that single large presynaptic terminals of TuLAL1 neurons enclose many small profiles (SPs) of TL neurons. The synaptic connections between these neurons are established by two types of synapses: divergent dyads and divergent tetrads. Our data support the assumption that these complexes are a highly conserved feature in the insect brain and play an important role in reliable signal transmission within the sky-compass pathway.

  2. Analysis of the Effects of Normal Walking on Ankle Joint Contact Characteristics After Acute Inversion Ankle Sprain.

    Science.gov (United States)

    Bae, Ji Yong; Park, Kyung Soon; Seon, Jong Keun; Jeon, Insu

    2015-12-01

    To show the causal relationship between normal walking after various lateral ankle ligament (LAL) injuries caused by acute inversion ankle sprains and alterations in ankle joint contact characteristics, finite element simulations of normal walking were carried out using an intact ankle joint model and LAL injury models. A walking experiment using a volunteer with a normal ankle joint was performed to obtain the boundary conditions for the simulations and to support the appropriateness of the simulation results. Contact pressure and strain on the talus articular cartilage and anteroposterior and mediolateral translations of the talus were calculated. Ankles with ruptured anterior talofibular ligaments (ATFLs) had a higher likelihood of experiencing increased ankle joint contact pressures, strains and translations than ATFL-deficient ankles. In particular, ankles with ruptured ATFL + calcaneofibular ligaments and all ruptured ankles had a similar likelihood as the ATFL-ruptured ankles. The push off stance phase was the most likely situation for increased ankle joint contact pressures, strains and translations in LAL-injured ankles.

  3. cDNA sequences of two apolipoproteins from lamprey

    International Nuclear Information System (INIS)

    Pontes, M.; Xu, X.; Graham, D.; Riley, M.; Doolittle, R.F.

    1987-01-01

    The messages for two small but abundant apolipoproteins found in lamprey blood plasma were cloned with the aid of oligonucleotide probes based on amino-terminal sequences. In both cases, numerous clones were identified in a lamprey liver cDNA library, consistent with the great abundance of these proteins in lamprey blood. One of the cDNAs (LAL1) has a coding region of 105 amino acids that corresponds to a 21-residue signal peptide, a putative 8-residue propeptide, and the 76-residue mature protein found in blood. The other cDNA (LAL2) codes for a total of 191 residues, the first 23 of which constitute a signal peptide. The two proteins, which occur in the high-density lipoprotein fraction of ultracentrifuged plasma, have amino acid compositions similar to those of apolipoproteins found in mammalian blood; computer analysis indicates that the sequences are largely helix-permissive. When the sequences were searched against an amino acid sequence data base, rat apolipoprotein IV was the best matching candidate in both cases. Although a reasonable alignment can be made with that sequence and LAL1, definitive assignment of the two lamprey proteins to typical mammalian classes cannot be made at this point

  4. Report of Activity, 1996-1997-1998; Rapport d'activite 1996-1997-1998

    Energy Technology Data Exchange (ETDEWEB)

    Bizot, J C [ed.; Lab. de l' Accelerateur Lineaire, Paris-11 Univ., 91 - Orsay (France)

    1999-07-01

    This report describes the activity of Linear Accelerator Laboratory at Orsay on 1996, 1997, and 1998. The physics research is focused onto three issues. The first has as objective the precise test of standard model in the sector of gauge boson interactions at LEP (ALEPH, DELPHI) and HERA (H1) and in the sector of matter properties (tau lepton, b quark, CP violation and neutrino mass). The second is a search for high energy new particles, particularly the Higgs boson and the particles predicted by supersymmetry. Finally, there is an astrophysics program aiming at gravitational wave detection and precise measurement of the relic background radiation by gravitational lensing and of high energy photon showers. The LAL plays a foremost role in the construction of the large experiments ATLAS, NEMO, VIRGO (especially mechanics) and BABAR and LHCb (electronics). The computing sector entered a new phase of critical mutations (relating to new tools and languages). Reported are also the LAL contributions to the TTF injector, the test station installed at Hamburg for the future superconductor e{sup +}e{sup -} collider TESLA and the effort in superconductor accelerator R and D of the DAPNIA-IN2P3 French collaboration. An illustration of the LAL efforts for developing applications is the electron beam project ELYSE designed for chemical utilizations, based on the experience with the photon triggered gun CANDELA.

  5. Report of Activity, 1996-1997-1998

    International Nuclear Information System (INIS)

    Bizot, J.C.

    1999-01-01

    This report describes the activity of Linear Accelerator Laboratory at Orsay on 1996, 1997, and 1998. The physics research is focused onto three issues. The first has as objective the precise test of standard model in the sector of gauge boson interactions at LEP (ALEPH, DELPHI) and HERA (H1) and in the sector of matter properties (tau lepton, b quark, CP violation and neutrino mass). The second is a search for high energy new particles, particularly the Higgs boson and the particles predicted by supersymmetry. Finally, there is an astrophysics program aiming at gravitational wave detection and precise measurement of the relic background radiation by gravitational lensing and of high energy photon showers. The LAL plays a foremost role in the construction of the large experiments ATLAS, NEMO, VIRGO (especially mechanics) and BABAR and LHCb (electronics). The computing sector entered a new phase of critical mutations (relating to new tools and languages). Reported are also the LAL contributions to the TTF injector, the test station installed at Hamburg for the future superconductor e + e - collider TESLA and the effort in superconductor accelerator R and D of the DAPNIA-IN2P3 French collaboration. An illustration of the LAL efforts for developing applications is the electron beam project ELYSE designed for chemical utilizations, based on the experience with the photon triggered gun CANDELA

  6. Inhibition of lipopolysaccharide induced acute inflammation in lung by chlorination

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Jinshan; Xue, Jinling; Xu, Bi; Xie, Jiani [Environmental Simulation and Pollution Control State Key Joint Laboratory, School of Environment, Tsinghua University, Beijing 100084 (China); Qiao, Juan, E-mail: qjuan@tsinghua.edu.cn [Department of Chemistry, Tsinghua University, Beijing 100084 (China); Lu, Yun, E-mail: luyun@tsinghua.edu.cn [Environmental Simulation and Pollution Control State Key Joint Laboratory, School of Environment, Tsinghua University, Beijing 100084 (China)

    2016-02-13

    Highlights: • Chlorination is effective to reduce the inflammation inducing capacity of LPS in lung. • LAL-detected endotoxin activity is not correlated to the potency of inflammation induction. • Alkyl chain of LPS was chlorinated in chlorination process. • LPS aggregate size decreases after chlorination. - Abstract: Lipopolysaccharide (LPS, also called endotoxin) is a pro-inflammatory constituent of gram negative bacteria and cyanobacteria, which causes a potential health risk in the process of routine urban application of reclaimed water, such as car wash, irrigation, scenic water refilling, etc. Previous studies indicated that the common disinfection treatment, chlorination, has little effect on endotoxin activity removal measured by Limulus amebocyte lysate (LAL) assay. However, in this study, significant decrease of acute inflammatory effects was observed in mouse lung, while LAL assay still presented a moderate increase of endotoxin activity. To explore the possible mechanisms, the nuclear magnetic resonance (NMR) results showed the chlorination happened in alkyl chain of LPS molecules, which could affect the interaction between LPS and LPS-binding protein. Also the size of LPS aggregates was found to drop significantly after treatment, which could be another results of chlorination caused polarity change. In conclusion, our observation demonstrated that chlorination is effective to reduce the LPS induced inflammation in lung, and it is recommended to use health effect-based methods to assess risk removal of water treatment technologies.

  7. Report of Activity, 1996-1997-1998; Rapport d'activite 1996-1997-1998

    Energy Technology Data Exchange (ETDEWEB)

    Bizot, J.C. [ed.] [Lab. de l' Accelerateur Lineaire, Paris-11 Univ., 91 - Orsay (France)

    1999-07-01

    This report describes the activity of Linear Accelerator Laboratory at Orsay on 1996, 1997, and 1998. The physics research is focused onto three issues. The first has as objective the precise test of standard model in the sector of gauge boson interactions at LEP (ALEPH, DELPHI) and HERA (H1) and in the sector of matter properties (tau lepton, b quark, CP violation and neutrino mass). The second is a search for high energy new particles, particularly the Higgs boson and the particles predicted by supersymmetry. Finally, there is an astrophysics program aiming at gravitational wave detection and precise measurement of the relic background radiation by gravitational lensing and of high energy photon showers. The LAL plays a foremost role in the construction of the large experiments ATLAS, NEMO, VIRGO (especially mechanics) and BABAR and LHCb (electronics). The computing sector entered a new phase of critical mutations (relating to new tools and languages). Reported are also the LAL contributions to the TTF injector, the test station installed at Hamburg for the future superconductor e{sup +}e{sup -} collider TESLA and the effort in superconductor accelerator R and D of the DAPNIA-IN2P3 French collaboration. An illustration of the LAL efforts for developing applications is the electron beam project ELYSE designed for chemical utilizations, based on the experience with the photon triggered gun CANDELA.

  8. Inhibition of lipopolysaccharide induced acute inflammation in lung by chlorination

    International Nuclear Information System (INIS)

    Zhang, Jinshan; Xue, Jinling; Xu, Bi; Xie, Jiani; Qiao, Juan; Lu, Yun

    2016-01-01

    Highlights: • Chlorination is effective to reduce the inflammation inducing capacity of LPS in lung. • LAL-detected endotoxin activity is not correlated to the potency of inflammation induction. • Alkyl chain of LPS was chlorinated in chlorination process. • LPS aggregate size decreases after chlorination. - Abstract: Lipopolysaccharide (LPS, also called endotoxin) is a pro-inflammatory constituent of gram negative bacteria and cyanobacteria, which causes a potential health risk in the process of routine urban application of reclaimed water, such as car wash, irrigation, scenic water refilling, etc. Previous studies indicated that the common disinfection treatment, chlorination, has little effect on endotoxin activity removal measured by Limulus amebocyte lysate (LAL) assay. However, in this study, significant decrease of acute inflammatory effects was observed in mouse lung, while LAL assay still presented a moderate increase of endotoxin activity. To explore the possible mechanisms, the nuclear magnetic resonance (NMR) results showed the chlorination happened in alkyl chain of LPS molecules, which could affect the interaction between LPS and LPS-binding protein. Also the size of LPS aggregates was found to drop significantly after treatment, which could be another results of chlorination caused polarity change. In conclusion, our observation demonstrated that chlorination is effective to reduce the LPS induced inflammation in lung, and it is recommended to use health effect-based methods to assess risk removal of water treatment technologies.

  9. Detection of Endotoxin Contamination of Graphene Based Materials Using the TNF-α Expression Test and Guidelines for Endotoxin-Free Graphene Oxide Production.

    Directory of Open Access Journals (Sweden)

    Sourav P Mukherjee

    Full Text Available Nanomaterials may be contaminated with bacterial endotoxin during production and handling, which may confound toxicological testing of these materials, not least when assessing for immunotoxicity. In the present study, we evaluated the conventional Limulus amebocyte lysate (LAL assay for endotoxin detection in graphene based material (GBM samples, including graphene oxide (GO and few-layered graphene (FLG. Our results showed that some GO samples interfered with various formats of the LAL assay. To overcome this problem, we developed a TNF-α expression test (TET using primary human monocyte-derived macrophages incubated in the presence or absence of the endotoxin inhibitor, polymyxin B sulfate, and found that this assay, performed with non-cytotoxic doses of the GBM samples, enabled unequivocal detection of endotoxin with a sensitivity that is comparable to the LAL assay. FLG also triggered TNF-α production in the presence of the LPS inhibitor, pointing to an intrinsic pro-inflammatory effect. Finally, we present guidelines for the preparation of endotoxin-free GO, validated by using the TET.

  10. Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics.

    Science.gov (United States)

    Aguisanda, Francis; Yeh, Charles D; Chen, Catherine Z; Li, Rong; Beers, Jeanette; Zou, Jizhong; Thorne, Natasha; Zheng, Wei

    2017-06-28

    Wolman disease (WD) is a rare lysosomal storage disorder that is caused by mutations in the LIPA gene encoding lysosomal acid lipase (LAL). Deficiency in LAL function causes accumulation of cholesteryl esters and triglycerides in lysosomes. Fatality usually occurs within the first year of life. While an enzyme replacement therapy has recently become available, there is currently no small-molecule drug treatment for WD. We have generated induced pluripotent stem cells (iPSCs) from two WD patient dermal fibroblast lines and subsequently differentiated them into neural stem cells (NSCs). The WD NSCs exhibited the hallmark disease phenotypes of neutral lipid accumulation, severely deficient LAL activity, and increased LysoTracker dye staining. Enzyme replacement treatment dramatically reduced the WD phenotype in these cells. In addition, δ-tocopherol (DT) and hydroxypropyl-beta-cyclodextrin (HPBCD) significantly reduced lysosomal size in WD NSCs, and an enhanced effect was observed in DT/HPBCD combination therapy. The results demonstrate that these WD NSCs are valid cell-based disease models with characteristic disease phenotypes that can be used to evaluate drug efficacy and screen compounds. DT and HPBCD both reduce LysoTracker dye staining in WD cells. The cells may be used to further dissect the pathology of WD, evaluate compound efficacy, and serve as a platform for high-throughput drug screening to identify new compounds for therapeutic development.

  11. Minimum pricing of alcohol versus volumetric taxation: which policy will reduce heavy consumption without adversely affecting light and moderate consumers?

    Science.gov (United States)

    Sharma, Anurag; Vandenberg, Brian; Hollingsworth, Bruce

    2014-01-01

    We estimate the effect on light, moderate and heavy consumers of alcohol from implementing a minimum unit price for alcohol (MUP) compared with a uniform volumetric tax. We analyse scanner data from a panel survey of demographically representative households (n = 885) collected over a one-year period (24 Jan 2010-22 Jan 2011) in the state of Victoria, Australia, which includes detailed records of each household's off-trade alcohol purchasing. The heaviest consumers (3% of the sample) currently purchase 20% of the total litres of alcohol (LALs), are more likely to purchase cask wine and full strength beer, and pay significantly less on average per standard drink compared to the lightest consumers (A$1.31 [95% CI 1.20-1.41] compared to $2.21 [95% CI 2.10-2.31]). Applying a MUP of A$1 per standard drink has a greater effect on reducing the mean annual volume of alcohol purchased by the heaviest consumers of wine (15.78 LALs [95% CI 14.86-16.69]) and beer (1.85 LALs [95% CI 1.64-2.05]) compared to a uniform volumetric tax (9.56 LALs [95% CI 9.10-10.01] and 0.49 LALs [95% CI 0.46-0.41], respectively). A MUP results in smaller increases in the annual cost for the heaviest consumers of wine ($393.60 [95% CI 374.19-413.00]) and beer ($108.26 [95% CI 94.76-121.75]), compared to a uniform volumetric tax ($552.46 [95% CI 530.55-574.36] and $163.92 [95% CI 152.79-175.03], respectively). Both a MUP and uniform volumetric tax have little effect on changing the annual cost of wine and beer for light and moderate consumers, and likewise little effect upon their purchasing. While both a MUP and a uniform volumetric tax have potential to reduce heavy consumption of wine and beer without adversely affecting light and moderate consumers, a MUP offers the potential to achieve greater reductions in heavy consumption at a lower overall annual cost to consumers.

  12. Determination of bacterial endotoxin (pyrogen) in radiopharmaceuticals by the gel clot method. Validation; Determinacao de endotoxina bacteriana (pirogenio) em radiofarmacos pelo metodo de formacao de gel. Validacao

    Energy Technology Data Exchange (ETDEWEB)

    Fukumori, Neuza Taeko Okasaki

    2008-07-01

    Before the Limulus amebocyte lysate (LAL) test, the only available means of pirogenicity testing for parenteral drugs and medical devices was the United States Pharmacopoeia (USP) rabbit pyrogen test. Especially for radiopharmaceuticals, the LAL assay is the elective way to determine bacterial endotoxin. The aim of this work was to validate the gel clot method for some radiopharmaceuticals without measurable interference. The FDA's LALTest guideline defines interference as a condition that causes a significant difference between the endpoints of a positive water control and positive product control series using a standard endotoxin. Experiments were performed in accordance to the USP bacterial endotoxins test in the {sup 131}I- m-iodobenzylguanidine; the radioisotopes Gallium-67 and Thallium-201; the lyophilized reagents DTPA, Phytate, GHA, HSA and Colloidal Tin. The Maximum Valid Dilution (MVD) was calculated for each product based upon the clinical dose of the material and a twofold serial dilution below the MVD was performed in duplicate to detect interferences. The labeled sensitivity of the used LAL reagent was 0.125 EU mL{sup -1} (Endotoxin Units per milliliter). For validation, a dilution series was performed, a twofold dilution of control standard endotoxin (CSE) from 0.5 to 0.03 EU mL{sup -1}, to confirm the labeled sensitivity of the LAL reagent being tested in sterile and non pyrogenic water, in quadruplicate. The same dilution series was performed with the CSE and the product in the 1:100 dilution factor, in three consecutive batches of each radiopharmaceutical. The products {sup 131}I-m-iodobenzylguanidine, Gallium-67, Thallium-201, DTPA, HSA and Colloidal Tin were found compatible with the LAL test at a 1:100 dilution factor. Phytate and GHA showed some interference in the gel clot test. Other techniques to determine endotoxins as the chromogenic (color development) and the turbidimetric test (turbidity development), were also assessed to get

  13. Minimum pricing of alcohol versus volumetric taxation: which policy will reduce heavy consumption without adversely affecting light and moderate consumers?

    Directory of Open Access Journals (Sweden)

    Anurag Sharma

    Full Text Available We estimate the effect on light, moderate and heavy consumers of alcohol from implementing a minimum unit price for alcohol (MUP compared with a uniform volumetric tax.We analyse scanner data from a panel survey of demographically representative households (n = 885 collected over a one-year period (24 Jan 2010-22 Jan 2011 in the state of Victoria, Australia, which includes detailed records of each household's off-trade alcohol purchasing.The heaviest consumers (3% of the sample currently purchase 20% of the total litres of alcohol (LALs, are more likely to purchase cask wine and full strength beer, and pay significantly less on average per standard drink compared to the lightest consumers (A$1.31 [95% CI 1.20-1.41] compared to $2.21 [95% CI 2.10-2.31]. Applying a MUP of A$1 per standard drink has a greater effect on reducing the mean annual volume of alcohol purchased by the heaviest consumers of wine (15.78 LALs [95% CI 14.86-16.69] and beer (1.85 LALs [95% CI 1.64-2.05] compared to a uniform volumetric tax (9.56 LALs [95% CI 9.10-10.01] and 0.49 LALs [95% CI 0.46-0.41], respectively. A MUP results in smaller increases in the annual cost for the heaviest consumers of wine ($393.60 [95% CI 374.19-413.00] and beer ($108.26 [95% CI 94.76-121.75], compared to a uniform volumetric tax ($552.46 [95% CI 530.55-574.36] and $163.92 [95% CI 152.79-175.03], respectively. Both a MUP and uniform volumetric tax have little effect on changing the annual cost of wine and beer for light and moderate consumers, and likewise little effect upon their purchasing.While both a MUP and a uniform volumetric tax have potential to reduce heavy consumption of wine and beer without adversely affecting light and moderate consumers, a MUP offers the potential to achieve greater reductions in heavy consumption at a lower overall annual cost to consumers.

  14. [Development and evaluation of a pyrogen test based on human whole blood

    Science.gov (United States)

    Hartung, Thomas; Fennrich, Stefan; Fischer, Matthias; Montag-Lessing, Thomas; Wendel, Albrecht

    1998-01-01

    When cells of the immune system, especially blood monocytes and macrophages, come into contact with pyrogenic (fever-inducing) contaminations, they secrete messenger molecules which initiate an hyperthermic reaction in the organism. Of this group of endogenous pyrogens, most is known about interleukin-1 (IL-1). A new pyrogen test makes use of this reaction as a system for detection: The substances which are to be screened are incubated with a small volume of blood from a healthy donor. Any pyrogens present induce the production of IL-1 which can be detected by ELISA. This test has a higher sensitivity and is more economical than the conventional pyrogen test in rabbits and furthermore reflects the reaction of the relevant species. In contrast to the customary alternative method, the Limulus amoebocyte lysate test (LAL), this test is not restricted to endotoxins from Gram-negative bacteria and is also not hindered by substances which bind endotoxins, such as blood proteins, to the same extent. Consequently, more than 50 non-endotoxin pyrogens have already been traced by this test. The whole blood test is even superior to the LAL in regard to the detection of endotoxins: in a comparison of about 60 endotoxins, there was a correlation of the potency of the individual endotoxins between the whole blood test and the pyrogen test in rabbits, but neither test correlated with the LAL test. In some cases, endotoxins with equal effects in the LAL test differed in potency in the human blood model by a factor of 10 000. A method has been developed by which cryopreserved blood can be put to use in the test. In this way, blood donations from a donor can be pre-tested so that uniform material may be employed in the test. This test opens up entirely new perspectives on pyrogen testing for Gram-positive or fungal pyrogens as well as in medicinal products. In addition, it could fill the dangerous security gap which might result from the limitations of testing medications and blood

  15. O hormônio de crescimento e a concentração de colágeno na cicatrização de feridas cutâneas de ratos

    Directory of Open Access Journals (Sweden)

    Biondo-Simões Maria de Lourdes Pessole

    2000-01-01

    Full Text Available Investiga-se a interferência do hormônio de crescimento no processo de cicatrização cutânea de ratos. Utilizaram-se 50 ratos machos com 170 dias de idade divididos em 2 grupos: controle (n=25 e experimento (n=25. Submeteram-se os ratos dos dois grupos à laparotomia mediana de 4 centímetros sob anestesia inalatória de éter etílico. Realizou-se a laparorrafia com 2 planos de sutura, o primeiro peritônio-músculo-aponevrótico e o segundo o da pele com chuleio contínuo de fio monofilamentar de náilon 4.0. Os animais do grupo experimento receberam 0,4U/kg/dia de hormônio de crescimento por via subcutânea diluído em 0,12 ml de água destilada e os do grupo controle recebiam igual volume do veículo pela mesma via. Realizaram-se as aferições após 36, 72, 168, 240 e 336 horas, ressecando-se retalhos da parede abdominal contendo as cicatrizes, que após preparação histológica e tratamento pelo Sirius red, forneceram a concentração do colágeno. O percentual da área de cicatriz ocupada por colágeno foi maior no grupo experimento nas 36 horas (p=0,0106, 72 horas (p=0,0089, 168 horas (p=0,0149 e 336 horas (p=0,0116. O percentual de colágeno I foi semelhante nos dois grupos nas 36 e 72 horas e maior no grupo experimento nas 168 horas (p=0,0218, 240 horas (p=0,0067 e nas 336 horas (p=0,0027. O percentual de colágeno III apareceu em proporção semelhante nos 2 grupos nas 36 e 72 horas. Sua proporção foi maior no grupo controle nas 168 horas (p=0,0216, 240 horas (p=0,0067 e 336 horas (p=0,0027. Estes dados permitiram concluir que o hormônio de crescimento levou a maior concentração de colágeno e acelerou a maturação das cicatrizes.

  16. Study on aerodynamics characteristics an urban concept car for energy-efficient race

    Science.gov (United States)

    Ambarita, H.; Siregar, M. R.; Kawai, H.

    2018-03-01

    "Horas Mesin USU" is a prototype of urban concept vehicle designed by University of Sumatera Utara to participate in the energy-efficient competition. This paper deals with a numerical study on aerodynamic characteristics of the Horas Mesin USU. The numerical analyses are carried out by solving the governing equations using CFD FLUENT commercial code. The turbulent flow is closed using k-epsilon turbulence model. In the results, pathline, velocity vector and pressure distribution are plotted. By using the pressure distributions, drag and lift coefficients are calculated. In order to make a comparison, the aerodynamic characteristics of the present design are compared with commercial city car Ford-Fiesta. The averaged drag coefficients of Horas Mesin USU and Ford-Fiesta are 0.24320 and 0.29598, respectively. On the other hand, the averaged lift coefficients of the Horas Mesin USU and Ford-Fiesta are 0.03192202 and 0.09485621, respectively. This fact suggests that Ford-Fiesta has a better aerodynamic performance in comparison with Horas Mesin USU. The flow field analysis shows that there are many modifications can be proposed to improve the aerodynamic performance of the Horas Mesin USU. It is suggested to perform further analysis to improve the aerodynamic performance of Horas Mesin USU.

  17. Obtención de un hidrolizado proteico por fermentación sumergida de plumas utilizando Bacillus spp

    OpenAIRE

    De Macedo, Manuel; Segura, Roxana; Piñero B., Judith; Coello, Nereida

    2009-01-01

    Se obtuvo un hidrolizado proteico a partir de la fermentación sumergida de las plumas por una cepa queratinolítica de Bacillus spp designada como LPB-2. El proceso se realizó en condiciones aeróbicas, utilizando un medio salino basal (pH 7,5), suplementado con 20 g/l de plumas molidas y un fermentador de 6 L de capacidad regulado a 40° C durante 26 horas. Mediante alimentaciones semi-continuas de sustrato, efectuadas cada 12 horas, se pudo prolongar el tiempo de fermentación hasta 58 horas. A...

  18. Comparative study between artificial xenodiagnosis performed immediately and four hours after venous punch

    OpenAIRE

    Castro, Cleudson; Santos, Martinho Candido A.; Silveira, Celeste Aida

    2004-01-01

    Foi realizado xenodiagnóstico artificial, imediatamente e quatro horas após a coleta do sangue, em 63 pacientes, sendo 29 (46%) do sexo masculino e 34 (54%) do sexo feminino. A idade mínima foi 18 anos e a máxima 68, sendo a idade média 39 anos. Onze (17,5%) pacientes apresentaram resultados positivos, sendo 8 (12,7%) no exame imediato e 7 (11,1%) no exame 4 horas após. Os oito pacientes do exame imediato apresentaram 17 pools positivos e os sete do xenodiagnóstico de quatro horas mostraram 1...

  19. Aspectos da ecologia dos flebótomos do Parque Nacional da Serra dos Orgãos, Rio de Janeiro: IV. Frequência mensal em armadilhas luminosas (Diptera, Psychodidae, Phlebotominae)

    OpenAIRE

    Aguiar,Gustavo Marins de; Vilela,Maurício Luiz; Schuback,Pedro D'Almeida; Soucasaux,Thaís; Azevedo,Alfredo Carlos R. de

    1985-01-01

    Durante dois anos completos - outubro de 1981 a setembro de 1983 - capturamos flebótomos em armadilhas luminosas no Parque Nacional da Serra dos Órgãos. As armadilhas eram colocadas, semanalmente, em pontos estratégicos na floresta, sempre no mesmo local e hora, ficando expostas por 12 horas. Foram gastas 732 horas e obtidos 2.730 flebótomos pertencentes a 17 espécies, quatro do gênero Brumptomyia França & Parrot, 1921 e 13 do gênero Lutzomyia França, 1924. a proporção de machos em relação ao...

  20. Prevalência de interações medicamentosas em unidades de terapia intensiva no Brasil

    OpenAIRE

    Carvalho,Rhanna Emanuela Fontenele Lima de; Reis,Adriano Max Moreira; Faria,Leila Márcia Pereira de; Zago,Karine Santana de Azevedo; Cassiani,Silvia Helena De Bortoli

    2013-01-01

    OBJETIVO: Determinar a prevalência de interações medicamentosas em unidades de terapia intensiva e analisar a significância clínica das interações identificadas. MÉTODOS: Estudo multicêntrico, transversal e retrospectivo desenvolvido com 1124 pacientes em sete unidades de terapia intensiva (UTI) de hospitais de ensino no Brasil. As informações sobre os medicamentos administrados com 24 horas e 120 horas de internação foram obtidas nas prescrições. RESULTADOS: Em 24 horas 70,6% dos pacientes a...

  1. Simulación para programar y controlar por monitoreo en tiempo real sistemas de atención hospitalaria

    OpenAIRE

    Cossa Cabanillas, Jesús Alberto; Cossa Cabanillas, Jesús Alberto

    2008-01-01

    Este trabajo de investigación pretende presentar una base cognoscitiva para la determinación de los productos terminados de las empresas prestadoras de salud. El camino, para lograr el cometido, se inicia buscando la forma de cuantificar la necesidad de recursos hospitalarios (horas médico, horas enfermeras, horas cama, etc.) que necesita un paciente para el tratamiento de su enfermedad. Así mismo se determinan y agrupan todos los tratamientos que consumen similares cantidades de estos re...

  2. Breastfeeding promotion and support strategies based on Paulo Freire's epistemological categories

    Directory of Open Access Journals (Sweden)

    Francisca Márcia Pereira Linhares

    2013-04-01

    Full Text Available OBJECTIVE: This study identified strategies for promoting breastfeeding involving pregnant women, breastfeeding women and actors of the social support network for the breastfeeding process. METHODS: This qualitative study was guided by action research and the focal group technique to collect data. Focal Group 1 consisted of four pregnant and six breastfeeding women; Focal Group 2 consisted of six family members; and Focal Group 3 consisted of thirteen health professionals. The focal groups were guided by the following questions: What breastfeeding promotion and support actions should be done? How should they be performed? Who should perform them? The conversation sunder went thematic content analysis and were interpreted in the light of Paulo Freire's theoretical constructs: dialogue, ethics and problematization. RESULTS: Four themes were emerged from the conversations: dialogue-based educational actions involving the social support network during the vital cycle; educational actions in schools; educational actions in the media; ongoing counseling at Family Health Units. CONCLUSION: The constructed strategies were centered on dialogue and active listening. Both should be present during the entire vital cycle and in the Family Health Strategy, and involve all actors of the social support network. These strategies may disrupt the unidirectional transmission of the educational practices that promote breastfeeding.

  3. Multilocus analysis of nucleotide variation and speciation in three closely related Populus (Salicaceae) species.

    Science.gov (United States)

    Du, Shuhui; Wang, Zhaoshan; Ingvarsson, Pär K; Wang, Dongsheng; Wang, Junhui; Wu, Zhiqiang; Tembrock, Luke R; Zhang, Jianguo

    2015-10-01

    Historical tectonism and climate oscillations can isolate and contract the geographical distributions of many plant species, and they are even known to trigger species divergence and ultimately speciation. Here, we estimated the nucleotide variation and speciation in three closely related Populus species, Populus tremuloides, P. tremula and P. davidiana, distributed in North America and Eurasia. We analysed the sequence variation in six single-copy nuclear loci and three chloroplast (cpDNA) fragments in 497 individuals sampled from 33 populations of these three species across their geographic distributions. These three Populus species harboured relatively high levels of nucleotide diversity and showed high levels of nucleotide differentiation. Phylogenetic analysis revealed that P. tremuloides diverged earlier than the other two species. The cpDNA haplotype network result clearly illustrated the dispersal route from North America to eastern Asia and then into Europe. Molecular dating results confirmed that the divergence of these three species coincided with the sundering of the Bering land bridge in the late Miocene and a rapid uplift of the Qinghai-Tibetan Plateau around the Miocene/Pliocene boundary. Vicariance-driven successful allopatric speciation resulting from historical tectonism and climate oscillations most likely played roles in the formation of the disjunct distributions and divergence of these three Populus species. © 2015 John Wiley & Sons Ltd.

  4. Abstract: SMAG PÅ SKOLEMAD

    DEFF Research Database (Denmark)

    Mithril, Charlotte Elisabeth; Kamuk, Anette

    En sund kost er vigtig for at sikre optimal vækst, udvikling og sundhed hos børn og unge. Der er derfor stor fokus på strategier, der kan fremme sundere kostvaner hos børn og unge, og her er skolemaden blevet et centralt omdrejningspunkt. Men hvad skal der til for, at eleverne spiser (og elsker...... velsmagende skolemad. Vi fandt, at hvis skolemadsordninger skal tilbyde velsmagende og sunde måltider skal det samtidig være et velfungerende aktiv for skolerne, hvor eleverne inddrages og bruger deres smag bevidst. Det anbefales at: 1) skolens ledelse samtænker skolemadsordninger og pædagogiske aktiviteter......) den sunde skolemad? Her spiller smagen en vigtig rolle. Hovedformålet har været at belyse praksis knyttet til arbejdet med smag i skolemadsordninger. Målet er at bidrage til, hvordan denne praksis kan understøttes og udvikles, således at smag som ressource og motivationsfaktor kan blive en drivkraft...

  5. Searching for stable Si(n)C(n) clusters: combination of stochastic potential surface search and pseudopotential plane-wave Car-Parinello simulated annealing simulations.

    Science.gov (United States)

    Duan, Xiaofeng F; Burggraf, Larry W; Huang, Lingyu

    2013-07-22

    To find low energy Si(n)C(n) structures out of hundreds to thousands of isomers we have developed a general method to search for stable isomeric structures that combines Stochastic Potential Surface Search and Pseudopotential Plane-Wave Density Functional Theory Car-Parinello Molecular Dynamics simulated annealing (PSPW-CPMD-SA). We enhanced the Sunders stochastic search method to generate random cluster structures used as seed structures for PSPW-CPMD-SA simulations. This method ensures that each SA simulation samples a different potential surface region to find the regional minimum structure. By iterations of this automated, parallel process on a high performance computer we located hundreds to more than a thousand stable isomers for each Si(n)C(n) cluster. Among these, five to 10 of the lowest energy isomers were further optimized using B3LYP/cc-pVTZ method. We applied this method to Si(n)C(n) (n = 4-12) clusters and found the lowest energy structures, most not previously reported. By analyzing the bonding patterns of low energy structures of each Si(n)C(n) cluster, we observed that carbon segregations tend to form condensed conjugated rings while Si connects to unsaturated bonds at the periphery of the carbon segregation as single atoms or clusters when n is small and when n is large a silicon network spans over the carbon segregation region.

  6. Searching for Stable SinCn Clusters: Combination of Stochastic Potential Surface Search and Pseudopotential Plane-Wave Car-Parinello Simulated Annealing Simulations

    Directory of Open Access Journals (Sweden)

    Larry W. Burggraf

    2013-07-01

    Full Text Available To find low energy SinCn structures out of hundreds to thousands of isomers we have developed a general method to search for stable isomeric structures that combines Stochastic Potential Surface Search and Pseudopotential Plane-Wave Density Functional Theory Car-Parinello Molecular Dynamics simulated annealing (PSPW-CPMD-SA. We enhanced the Sunders stochastic search method to generate random cluster structures used as seed structures for PSPW-CPMD-SA simulations. This method ensures that each SA simulation samples a different potential surface region to find the regional minimum structure. By iterations of this automated, parallel process on a high performance computer we located hundreds to more than a thousand stable isomers for each SinCn cluster. Among these, five to 10 of the lowest energy isomers were further optimized using B3LYP/cc-pVTZ method. We applied this method to SinCn (n = 4–12 clusters and found the lowest energy structures, most not previously reported. By analyzing the bonding patterns of low energy structures of each SinCn cluster, we observed that carbon segregations tend to form condensed conjugated rings while Si connects to unsaturated bonds at the periphery of the carbon segregation as single atoms or clusters when n is small and when n is large a silicon network spans over the carbon segregation region.

  7. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 399 ... ... Products against Aluminium Fluoride Induced Oxidative Stress, Abstract PDF ... Vol 4, No 2 (2015), Appearance and Chemical Control of White ... and Opportunities of Wetlands Management in Bule Hora Woreda, ...

  8. Análisis del perfil de compuestos volátiles del mango (mangifera indica l. var. tommy atkins) tratado por métodos combinados

    OpenAIRE

    Moreno, Angélica; León, David F.; Giraldo, Germán A.; Ríos, Eunice

    2010-01-01

    Se evaluó el perfil de compuestos volátiles del mango (Mangifera indica L. Var. Tommy Atkins) al ser tratado con la combinación de los métodos de deshidratación osmótica con o sin pulso de vacío (DOPV y DO) y con secado por aire caliente o con vacío (SAC y VAC). El tiempo utilizado en la cinética del proceso de DO fue de 42 horas y la DOPV de 30 horas; en los procesos de secado, el SAC se realizó durante 24 horas y el VAC requirió 40 horas. En el perfil de compuestos volátiles del mango fresc...

  9. ANÁLISIS DEL PERFIL DE COMPUESTOS VOLÁTILES DEL MANGO (Mangifera indica L. Var. Tommy Atkins) TRATADO POR MÉTODOS COMBINADOS

    OpenAIRE

    Angélica Moreno; David F. León; Germán A. Giraldo; Eunice Ríos

    2010-01-01

    Se evaluó el perfil de compuestos volátiles del mango (Mangifera indica L. Var. Tommy Atkins) al ser tratado con la combinación de los métodos de deshidratación osmótica con o sin pulso de vacío (DOPV y DO) y con secado por aire caliente o con vacío (SAC y VAC). El tiempo utilizado en la cinética del proceso de DO fue de 42 horas y la DOPV de 30 horas; en los procesos de secado, el SAC se realizó durante 24 horas y el VAC requirió 40 horas. En el perfil de compuestos volátiles del mango fresc...

  10. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    management in Bule Hora Woreda so as to enhance th increase the advantages ..... threats to the wetlands and evaluate the impact of wetland changes on local .... (1998), the water, soils, plants, hydrological and ecological characteristics of.

  11. Zaniklý těžební areál U Všech Svatých na Horách Kutných

    Czech Academy of Sciences Publication Activity Database

    Velímský, Filip

    2012-01-01

    Roč. 12, prosinec (2012), s. 203-210 ISSN 1801-5972 Institutional research plan: CEZ:AV0Z80020508 Keywords : Kutná Hora * archaeology * Middle Ages * silver mining Subject RIV: AC - Archeology, Anthropology, Ethnology

  12. Interferencias en la validación del ensayo de lisado de amebocitos de Limulus para oxitetraciclina 50 mg/mL Interferences in the validation of the Limulus amebocyte lysate for oxytetracyline 50 mg/mL

    Directory of Open Access Journals (Sweden)

    Olga Osorio Rojas

    2007-04-01

    Full Text Available El análisis de endotoxina por medio del lisado de amebocitos de Limulus (LAL es uno de los principales ensayos en el control de calidad de la fabricación de inyectables por su repercusión en la salud humana y animal, razón por la que se requiere la validación de la técnica para los productos parenterales. Se empleó el método de LAL gel-clot para validar la detección de endotoxina bacteriana en la oxitetraciclina producida por un laboratorio maquilador de productos farmacéuticos veterinarios de Bogotá, Colombia. Para este objetivo se tomaron muestras al inicio, intermedio y final de 3 lotes diferentes del medicamento y se realizó la prueba de validación tal y como lo especifica la United States Pharmacopea XXV. Los resultados para la máxima dilución válida del producto (1:80 de la prueba Spike mostraron el 100 % de inhibición hasta la dilución 1:16 y 0 % de inhibición en las siguientes diluciones. En la prueba Unspike se muestra un realce de la prueba a partir de la dilución 1:32. El rótulo para un reactivo de LAL con sensitividad (l de 0,25 unidades de endotoxinas por mililitro (UE/mL y el operario que realizó el ensayo quedaron validados.The endotoxin analysis by the Limulus amebocyte lysate (LAL assay is one of the main tests in the quality control of the manufacture of injectables due to their repercussion on human and animal health. That's why the validation of the technique is required for parenteral products. The LAL gel-clot method was used to validate the detection of bacterial endotoxin in the oxytetracycline produced by a veterinary pharmaceutical laboratory of Bogota-Colombia. To this end, samples were taken at the beginning, interval and end of 3 different batches of the medicine and the test of validation was made just as it is specified in the United States Pharmacopea XXV. The results for the Maximum Valid Dilution of the product (1:80 of the Spike test showed a 100 % of inhibition until dilution 1:16, and 0

  13. Translations on Narcotics and Dangerous Drugs No. 275.

    Science.gov (United States)

    1976-12-09

    8217Vast’ Drug Network (HERALD, 25 Nov 76) l7 CHILE Marihuana Grower, Trafficker Arrested (LA TERCERA DE LA HORA, 10 Nov 76) 18 COLOMBIA...17 CHILE MARIHUANA. GROWER, TRAFFICKER ARRESTED Santiago LA TERCERA DE IA HORA in Spanish 10 Nov 76 p 27 [Text] Between 250,000 and 300,000...mountainous Aguas Negras region in the jurisdiction of Solano, where seven per- sons were arrested and a very complete laboratory was seized, together

  14. Supervivencia de Trypanosoma cruzi en bebidas experimentalmente contaminadas

    Directory of Open Access Journals (Sweden)

    Diana Carolina Suárez

    2012-03-01

    Conclusiones. La cepa DS de T. cruzi sobrevivió en todas las bebidas por más de 24 horas después de la contaminación y se observó un tiempo de supervivencia de 384 horas a temperatura de refrigeración en el jugo de guanábana.   DOI: http://dx.doi.org/10.7705/biomedica.v32i1.371

  15. Estimating KC-137 Aircraft Ownership Costs in the Brazilian Air Force

    Science.gov (United States)

    1997-06-01

    voadas pelo esquad~o, 1996 por ano (soma de todlas as aeronaves) Consumno de combustivel por hora Consumno de 6Ieo por hora Consumo de outros...Manutengdo 2.2.1.1 Materiais de Aeronaves Este parece ser urn item dificil. Ele inclui o custo de materials de consumo e pegas usados regularmente...itens, repar~veis, consumo , ferramentas, etc. Ser6 que o suprirnento do Parque tern como fornecer este apanhado geral? Se for necess~rio (e possivel

  16. CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report.

    Science.gov (United States)

    Zhang, Hanrui; Shi, Jianting; Hachet, Melanie A; Xue, Chenyi; Bauer, Robert C; Jiang, Hongfeng; Li, Wenjun; Tohyama, Junichiro; Millar, John; Billheimer, Jeffrey; Phillips, Michael C; Razani, Babak; Rader, Daniel J; Reilly, Muredach P

    2017-11-01

    To gain mechanistic insights into the role of LIPA (lipase A), the gene encoding LAL (lysosomal acid lipase) protein, in human macrophages. We used CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) technology to knock out LIPA in human induced pluripotent stem cells and then differentiate to macrophage (human-induced pluripotent stem cells-derived macrophage [IPSDM]) to explore the human macrophage LIPA loss-of-function phenotypes. LIPA was abundantly expressed in monocyte-derived macrophages and was markedly induced on IPSDM differentiation to comparable levels as in human monocyte-derived macrophage. IPSDM with knockout of LIPA ( LIPA -/- ) had barely detectable LAL enzymatic activity. Control and LIPA -/- IPSDM were loaded with [ 3 H]-cholesteryl oleate-labeled AcLDL (acetylated low-density lipoprotein) followed by efflux to apolipoprotein A-I. Efflux of liberated [ 3 H]-cholesterol to apolipoprotein A-I was abolished in LIPA -/- IPSDM, indicating deficiency in LAL-mediated lysosomal cholesteryl ester hydrolysis. In cells loaded with [ 3 H]-cholesterol-labeled AcLDL, [ 3 H]-cholesterol efflux was, however, not different between control and LIPA -/- IPSDM. ABCA1 (ATP-binding cassette, subfamily A, member 1) expression was upregulated by AcLDL loading but to a similar extent between control and LIPA -/- IPSDM. In nonlipid loaded state, LIPA -/- IPSDM had high levels of cholesteryl ester mass compared with minute amounts in control IPSDM. Yet, with AcLDL loading, overall cholesteryl ester mass was increased to similar levels in both control and LIPA -/- IPSDM. LIPA -/- did not impact lysosomal apolipoprotein-B degradation or expression of IL1B , IL6 , and CCL5. CONCLUSIONS: LIPA -/- IPSDM reveals macrophage-specific hallmarks of LIPA deficiency. CRISPR/Cas9 and IPSDM provide important tools to study human macrophage biology and more broadly for future studies of disease-associated LIPA genetic variation in human

  17. A study of the Al-rich part of the Al-Re alloy system

    International Nuclear Information System (INIS)

    Balanetskyy, S.; Grushko, B.

    2008-01-01

    The Al-rich part of the Al-Re phase diagram was reinvestigated by scanning and transmission electron microscopy, powder X-ray diffraction and differential thermal analysis. The earlier reported Al 12 Re, Al 6 Re, and Al 11 Re 4 phases were confirmed. Close to the Al 4 Re composition a high-temperature h-Al 4 Re and a low-temperature l-Al 4 Re phase were found to be formed at slightly different compositions. Both exhibited compositional ranges. A new phase was revealed close to the Al 3 Re composition. The Al 11 Re 4 phase is formed congruently at 1650 deg. C, Al 3 Re peritectically at 1610 deg. C, h-Al 4 Re peritectically at 1410 deg. C, l-Al 4 Re peritectically at ∼1000 deg. C, Al 6 Re peritectically at 813 deg. C and Al 12 Re peritectically at 746 deg. C. Finally, the Al 12 Re-(Al) eutectic is formed at 658 deg. C. The Al 3 Re and h-Al 4 Re are decomposed by eutectoid reactions at ∼946 and 833 deg., respectively. The structure of the h-Al 4 Re phase has not yet been clarified, but it is distinctly different from the Al 4 W phase suggested earlier. The structure of l-Al 4 Re was confirmed. The Al 3 Re phase was found to have a monoclinic structure with a = 0.5180(4) nm, b = 3.97641(9) nm, c = 0.4955(3) nm and β = 99.55(7) o

  18. Laser-assisted lipolysis in the treatment of gynecomastia: a prospective study in 28 patients.

    Science.gov (United States)

    Trelles, M A; Mordon, S R; Bonanad, E; Moreno Moraga, J; Heckmann, A; Unglaub, F; Betrouni, N; Leclère, F M

    2013-02-01

    Gynecomastia is the most common breast pathology. Numerous excisions and liposuction techniques have been described to correct bilateral male breast enlargement. Recently, there has been a shift from the open approach to minimally invasive techniques. This article reports a 5-year experience using laser-assisted lipolysis (LAL) to treat gynecomastia, and describes the surgical technique. Between January 2006 and December 2010, a total of 28 patients with bilateral gynecomastia were treated with LAL. Patients had a mean age of 36.5 years (range 24 to 56 years). LAL was performed with a 980-nm diode laser (continuous emission, 15 W power, 8-12 kJ total energy per breast) after tumescent anesthetic infiltration. The breast was evaluated objectively by two physicians who compared chest circumference and photographs. Patients were also asked to score the results using a visual analogue scale: 75 to 100 (very good), 50-74 (good), 25 to 49 (fair) and 0 to 24 (poor). The postoperative period for all patients was incident-free. After 6 months, 18 patients (64.3%) scored the results as "very good", 6 as "good" (21.4%), 3 as "fair" (10.7%) and 1 "poor" (3.6%). Mean chest circumferences pre- and postoperatively were, respectively, 117.4 ± 11.1 cm and 103.3 ± 7.5 cm (p gynecomastia is safe and produces significant effects on fatty tissue, with a reduction in breast volume, together with significant skin tightening. Provided an appropriate amount of energy is delivered by an experienced operator, the results are both significant and consistent.

  19. Determination of Interference During In Vitro Pyrogen Detection: Development and Characterization of a Cell-Based Assay.

    Science.gov (United States)

    Palma, Linda; Rossetti, Francesca; Dominici, Sabrina; Buondelmonte, Costantina; Rocchi, Marco B L; Rizzardi, Gian P; Vallanti, Giuliana; Magnani, Mauro

    Contamination of pharmaceutical products and medical devices with pyrogens such as endotoxins is the most common cause of systemic inflammation and, in worst cases, of septic shock. Thus, quantification of pyrogens is crucial. The limulus amebocyte lysate (LAL)-based assays are the reference tests for in vitro endotoxin detection, in association with the in vivo rabbit pyrogen test (RPT), according to European Pharmacopoeia (EP 2.6.14), and U.S. Pharmacopoeia (USP ). However, several substances interfere with LAL assay, while RPT is not accurate, not quantitative, and raises ethical limits. Biological assays, as monocyte activation tests, have been developed and included in European Pharmacopoeia (EP 7.0; 04/2010:20630) guidelines as an alternative to RPT and proved relevant to the febrile reaction in vivo. Because this reaction is carried out by endogenous mediators under the transcriptional control of nuclear factor-kappaB (NF-kappaB), we sought to determine whether a NF-kappaB reporter-gene assay, based on MonoMac-6 (MM6) cells, could reconcile the basic mechanism of innate immune response with the relevance of monocytoid cell lines to the organism reaction to endotoxins. This article describes both optimization and characterization of the reporter cells-based assay, which overall proved the linearity, accuracy, and precision of the test, and demonstrated the sensitivity of the assay to 0.24 EU/mL endotoxin, close to the pyrogenic threshold in humans. Moreover, the assay was experimentally compared to the LAL test in the evaluation of selected interfering samples. The good performance of the MM6 reporter test demonstrates the suitability of this assay to evaluate interfering or false-positive samples.

  20. New Applications of the Human Whole Blood Pyrogen Assay (PyroCheck).

    Science.gov (United States)

    Fennrich; Wendel; Hartung

    1999-01-01

    The absence of pyrogens in injectable drugs is an indispensable safety control because contaminants causing fever pose a life-threatening risk to the patient resulting in the worst case in death by shock. When fever- inducing agents, i.e.pyrogens, come into contact with the immunocompetent cells in blood, these cells release mediators which transmit the fever signal to the thermoregulatory centre of the brain. The Phamocopoeia lists currently two test systems for pyrogenicity: 1. The in vivo rabbit pyrogen test which measures the fever reaction following injection of the sample to the animals. 2. The in vitro Limulus Amebocyte Lysate assay (LAL) which measures the coagulation in a lysate prepared from the blood of the horseshoe crab specifically initiated by endotoxins, i.e. cell wall components from Gram-negative bacteria. The new test presented here (PyroCheck) exploits the reaction of monocytes/macrophages for the detection of pyrogens: human whole blood taken from healthy volunteers is incubated in the presence of the test sample in any form, be it a solution, a powder or even solid material. Pyrogenic contaminations initiate the release of the "endogenous pyrogen" Interleukin-1beta determined by ELISA after a fixed incubation time. The technology presently listed in the Pharmacopoeia is limited to parenteralia (rabbit test: biologicals and pharmaceuticals, LAL: predominantly pharmaceuticals). In the EU Medical Devices Directive from 1995 the rabbit pyrogen test for medical products is in some cases requested. (in some cases LAL of an eluate from the device). However, pyrogen-testing needs to cover also innovative high-tech products such as medical devices (implants, medical plastic materials, dialysis machines), cellular therapies and species-specific agents (e.g. recombinant proteins). Here we report that the human blood test PyroCheck is suitable for testing filters in air quality control as well as for assessing medical devices and biocompatibility

  1. Chelating extractants of improved selectivity. Progress report, 1 August 1979-31 July 1980

    International Nuclear Information System (INIS)

    1980-01-01

    During the current contract year, mixed ligand chelate extraction systems for separating lanthanides was extended to elucidating the underlying reasons for the observed enhancement by quaternary ammonium salts. Equilibrium studies reveal the formation of anionic complexes (LnL 4 .HL - ) (where HL is 8-quinolinol) that was extracted when paired with a quaternary ammonium ion. Lathanum, as a lone exception was extracted as R 4 N + , LaL 4 - . Work is underway in the application of similar extractants, 5,7-dibromo-8-quinolinol and Kelex 100 (a 7-alkenyl-8-quinolinol) to the separation of lanthanides

  2. Selección por conformación de reproductores de tilapia roja Oreochromis sp., mediante prueba de progenie

    Directory of Open Access Journals (Sweden)

    Hermes Pineda S.

    2013-10-01

    Full Text Available Objetivo. Contribuir con la caracterización estadística y genotípica (media, media del error estándar, varianza y heredabilidad de la Longitud Total (LT y Longitud Altura del Lomo (LAL, y plantear una estrategia de selección para mejorar la calidad de la semilla de reproductores de tilapia roja Oreochromis sp. Materiales y métodos. El proyecto se realizó en la Granja Experimental y de Producción Piscícola (PCJIC, a un Km del municipio de San Jerónimo, distante 61 Km al Occidente de Medellín (Antioquia. Se conformaron tres grupos de cruzamientos, cada uno en proporción de 3 hembras por 1 macho así: un cruce Hembras Blancas (HB x Macho Rojo (MR y dos cruces Hembras Blancas (HB x Macho Blanco (MB. Las progenies fueron medidas a los 60 días post eclosión, teniendo en cuenta los supuestos estadísticos. Resultados. El ANOVA mostró que las progenies difieren significativamente (p<0.001 para ambas variables continuas. La LT fue mayor para la progenie del cruzamiento HBxMB sin reversión (8.04±1.04cm y LAL fue mayor para la progenie HBxMR (2.33±0.44cm. La correlación pareada entre las variables fue altamente significativa (r≥0.79, p<0.001. Las heredabilidades fueron 0.59 (LT y 0.64 (LAL. Los porcentajes de manchas en las progenies fueron HBxMR (34% y HBxMB no revertida (66%. Conclusiones. La progenie del Grupo 1 HBxMR tuvo los reproductores para una mejor selección por conformación, por lo que se sugiere aumentar el número de animales con mayor LAL. También, considerar la menor cantidad de manchas oscuras y realizar un manejo de reproductores por grupos independientes para selección masal.

  3. Quality control protocols for radiodiagnosis agents and radiopharmaceuticals

    International Nuclear Information System (INIS)

    Robles, A.; Condor, M.; Caballero, J.; Morote, M.; Garcia, C.; Benites, M.

    1997-01-01

    Based on the compilation of pharmacopoeia methods, literature, manuals and other information developed in our laboratory, protocols have been prepared to carry out quality controls for radiodiagnosis agents (RDA), better known as kits and RDA labelled with Tc99m. Quality control protocols cover physicochemical and biological controls. Physicochemical controls described for RDA include physical characteristics, particle size and number, pH, chemical identification, humidity, tin II; whereas biological controls include sterility, acute toxicity and bacterial endotoxin determination (LAL). Physicochemical controls described for radiopharmaceuticals labelled with Tc99m are pH and radiochemical purity; while biological distribution is described as a biological control

  4. Preparation of antimony sulfide semiconductor nanoparticles by pulsed laser ablation in liquid

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Ren-De, E-mail: son003@sekisui.com [Research & Development Institute, High Performance Plastics Company, Sekisui Chemical Co., Ltd. 2-1 Hyakuyama, Shimamoto-Cho, Mishima-Gun, Osaka, 618-0021 (Japan); Tsuji, Takeshi [Interdisciplinary Graduate School of Science and Engineering, Shimane University, 1060 Nishikawatsu-Cho, Matsue, 690-8504 (Japan)

    2015-09-01

    Highlights: • Pulsed laser ablation in liquid (LAL) was applied to prepare antimony sulfide nanoparticles (Sb{sub 2}S{sub 3} NPs). • Sb{sub 2}S{sub 3} NPs with a stoichiometric composition were successfully prepared by LAL in water without using any surfactants or capping agents. • Thus-prepared Sb{sub 2}S{sub 3} NPs showed low-temperature crystallization and melting at a temperature low as 200 °C. • The NPs-coated Sb{sub 2}S{sub 3} thin film showed comparable semiconductor properties (carrier mobility and carrier density) to the vacuum deposited one. • Byproducts such as CS{sub 2}, CH{sub 4} and CO were detected by GC-MS analysis when LAL was performed in organic solvent. • The LAL-induced decomposition mechanism of Sb{sub 2}S{sub 3} and organic solvents was discussed based on the GC-MS results. - Abstract: In this paper, we report on the synthesis of antimony sulfide (Sb{sub 2}S{sub 3}) semiconductor nanoparticles by pulsed laser ablation in liquid without using any surfactants or capping agents. Different results were obtained in water and organic solvents. In the case of water, Sb{sub 2}S{sub 3} nanoparticles with chemical compositions of stoichiometry were successfully prepared when laser irradiation was performed under the condition with the dissolved oxygen removed by argon gas bubbling. It was shown that thus-obtained Sb{sub 2}S{sub 3} nanoparticles exhibit features of not only low-temperature crystallization but also low-temperature melting at a temperature as low as 200 °C. Nanoparticle-coated Sb{sub 2}S{sub 3} thin films were found to show good visible light absorption and satisfying semiconductor properties (i.e., carrier mobility and density), which are essential for photovoltaic application. On the other hand, in the case of organic solvents (e.g., acetone, ethanol), such unexpected byproducts as CS{sub 2}, CO and CH{sub 4} were detected from the reaction system by GC-MS analysis, which suggests that both Sb{sub 2}S{sub 3} and organic

  5. 22 Étude des propriétés structurales, optiques et électriques des ...

    African Journals Online (AJOL)

    herve tchognia

    Figure 1 : Spectres de diffraction des rayons X des couches minces de ZnO préparées avec différents pourcentages de l'Al. Les grains de films non dopés et dopés ont cristallisés préférentiellement suivant le plan de réflexion (002). Aucun pic supplémentaire n'a été détecté. Le film dopé 2% Al a montré la plus haute ...

  6. PcaO Positively Regulates pcaHG of the β-Ketoadipate Pathway in Corynebacterium glutamicum▿

    OpenAIRE

    Zhao, Ke-Xin; Huang, Yan; Chen, Xi; Wang, Nan-Xi; Liu, Shuang-Jiang

    2010-01-01

    We identified a new regulator, PcaO, which is involved in regulation of the protocatechuate (PCA) branch of the β-ketoadipate pathway in Corynebacterium glutamicum. PcaO is an atypical large ATP-binding LuxR family (LAL)-type regulator and does not have a Walker A motif. A mutant of C. glutamicum in which pcaO was disrupted (RES167ΔpcaO) was unable to grow on PCA, and growth on PCA was restored by complementation with pcaO. Both an enzymatic assay of PCA 3,4-dioxygenase activity (encoded by p...

  7. VALORACIÓN DE ENDOTOXINAS BACTERIANAS EN RANITIDINA Y PENICILINA G SÓDICA INYECTABLE MEDIANTE LA PRUEBA DE LISADO DEL AMEBOCITO DE Limulus

    OpenAIRE

    C. Carrillo; J. Ospina; D. Aldana; J. Arias; C. Echeverri

    2006-01-01

    Se realizó la estandarización y valoración de endotoxinas bacterianas por la técnica de Lisado del Amebocito de Limulus (LAL) para dos productos farmacéuticos: penicilina G sódica y ranitidina inyectable por el método de gelificación. Para ello se tomaron tres muestras de tres lotes diferentes; las muestras fueron escogidas al azar y se tomó una muestra del principio, una de la mitad y otra del final de la producción para cada lote muestreado. Con las muestras de cada lote se realizó un pool,...

  8. Evaluación del método cromogénico cinético para la determinación de endotoxinas bacterianas en el inyectable succinilcolina infantil 100 mg.

    OpenAIRE

    Nancy Burguet-Lago; Aylid Suárez-Castillo; Yamilka Herrera-Ledesma

    2015-01-01

    El objetivo del presente trabajo fue evaluar el método de lisado de amebocitos del Limulus (LAL) en su variante cromogénica cinética para la determinación de endotoxinas bacterianas en el inyectable succinilcolina infantil 100 mg. Esta variante moni torea el desarrollo de color a través del tiempo y emplea una curva estándar representada por el tiempo de reacción en función de la concentración conocida de endotoxinas, en un rango de 0,005 a 50 UE/mL...

  9. Defense Against Threat. Threat Recognition and Analysis Project

    Science.gov (United States)

    1975-09-01

    ONN; ND PHI COiiBAT SIN TAI); COIi^UNIST INSURGENCY, 32, TIN FOOD 18, hANUFACTURES 18, 18, TlliBER 17, SIN 22, MALAYSIA l.AL 820 6 75...FIN:GEN MONTI EL; DEF:COL SANCHEZ; AREA:0,053,938; POP:001,990, 000; GNP:0,000,730,000, 000; GNPPC:0366; BOR:HüN; BOR:COS; ÜRG:UN0...MOZ FUR LISBON,POR COMMUNIST PARTY DEMANDS CENSORSHIP OF FOREIGN PRESS,THE TWO PAKTIES OPPOSING THE AFM TOTALLY COLLAPSE LEAVING THE ARMED FORCES

  10. Quality control protocols for radiodiagnosis agents and radiopharmaceuticals; Protocolos de control de calidad para agentes de radiodiagnostico y radiofarmacos

    Energy Technology Data Exchange (ETDEWEB)

    Robles, A; Condor, M; Caballero, J; Morote, M; Garcia, C; Benites, M

    1997-07-01

    Based on the compilation of pharmacopoeia methods, literature, manuals and other information developed in our laboratory, protocols have been prepared to carry out quality controls for radiodiagnosis agents (RDA), better known as kits and RDA labelled with Tc99m. Quality control protocols cover physicochemical and biological controls. Physicochemical controls described for RDA include physical characteristics, particle size and number, pH, chemical identification, humidity, tin II; whereas biological controls include sterility, acute toxicity and bacterial endotoxin determination (LAL). Physicochemical controls described for radiopharmaceuticals labelled with Tc99m are pH and radiochemical purity; while biological distribution is described as a biological control.

  11. Photoemission in nanosecond and picosecond regimes obtained from macro and micro cathodes

    International Nuclear Information System (INIS)

    Boussoukaya, M.; Bergeret, H.; Chehab, R.; Leblond, B.; Franco, M.

    1987-03-01

    For Lasertron studies at LAL, results obtained from tests on different photocathodes are given below. Using respectively two Nd: YAG lasers (a nanosecond one and a picosecond one) we have determined the level and the intensity of pulsed photoemission and the photoelectric yield in UV, green and infrared lights. We obtained a total current of more than 1 A with nanosecond width from a single W needle, and photoconversion yield of more than 1 was reached in green and UV lights. In classical pulsed photoemission, obtained photoconversion yield from LaB 6 photocathode was of about 10 -3 in higher fields

  12. Comportement à la corrosion intrinsèque de couches minces à base ...

    African Journals Online (AJOL)

    Mo, le Mg et les Terres rares Y et Gd. Le réacteur de pulvérisation ... dépôts réalisés sur substrat en verre servent pour la caractérisation de leur .... en Terres rares. Ceci pourrait s'expliquer par la différence de rayon atomique entre ces deux terres rares et celui de l'Al pur. (rY = 0,177 nm, rGd = 0,178 nm et. rAl = 0,143 nm).

  13. Evaluación de la carga laboral en residentes chilenos de especialidades y subespecialidades médicas

    Directory of Open Access Journals (Sweden)

    Luis Antonio Díaz Piga

    2016-10-01

    Full Text Available Introducción: La sobrecarga laboral horaria es un importante problema en los programas de especialización médica. Se asocia a mayor prevalencia de depresión, burnout, deserción, e impacta en la calidad de vida de los residentes. Nuestro objetivo fue cuantificar las horas semanales de carga laboral horaria en residentes de especialidad y subespecialidad de la Pontificia Universidad Católica de Chile (PUC. Métodos: Se realizó una encuesta electrónica a los residentes de especialidad y subespecialidad de la PUC (2013. Ésta incluyó autoreporte de horas semanales trabajadas (jornada habitual, turnos presenciales y turnos de llamada. Para el análisis se consideraron sólo las horas presenciales (jornada habitual y turnos presenciales. Resultados: Se obtuvo 415 respuestas (tasa de respuesta 86%. Los residentes de especialidad reportaron una jornada de 52,8 ± 20,3 horas semanales más un promedio de 22,6 ± 22,5 horas de turnos presenciales semanales. Los residentes de programas de subespecialidad reportaron una jornada de 55,9 ± 22,2 horas semanales más un promedio de 23 ± 3,9 horas de turnos presenciales semanales. De los 53 programas evaluados, el 22,6% sobrepasó el límite recomendado  por  la Dirección de Postgrado PUC (80 horas semanales. Cinco programas reportaron 90-100 horas semanales (todas especialidades o subespecialidades quirúrgicas y 7 programas reportaron 80-90 horas semanales (3 subespecialidades médicas, 1 subespecialidad quirúrgica, 2 especialidades médicas y 1 especialidad quirúrgica. Conclusión: Los residentes de especialidades y subespecialidades médicas en la PUC están sometidos a una carga horaria significativa. Los programas quirúrgicos presentaron la mayor sobrecarga horaria presencial, con un promedio mayor al recomendado a nivel internacional.

  14. Efecto del fotoperiodo y la intensidad lumínica sobre la esporulación de Peronospora sparsa Berkeley, bajo condiciones controladas

    Directory of Open Access Journals (Sweden)

    Soto S. Johana Carolina

    2009-08-01

    Full Text Available

    El mildeo velloso de la rosa, producido por Peronospora sparsa, es una de las enfermedades más limitantes y costosas en los cultivos comerciales de rosa en Colombia. La estrecha relación de la enfermedad con las condiciones climáticas ha llevado a realizar estudios del parásito en condiciones microclimáticas controladas. Esta investigación buscó ahondar en el conocimiento de la biología del mildeo velloso de la rosa, evaluando para ello el efecto del fotoperiodo y la intensidad lumínica sobre la esporulación del parásito cultivado en folíolos de rosa en cámara húmeda bajo condiciones ambientales controladas. Se evaluaron los siguientes fotoperiodos: 24 horas bajo una intensidad lumínica de 1.000 lux; 8, 12 y 24 horas luz a 790 lux; 8, 16 y 24 horas a 560 lux; 12 horas a 120 lux, y finalmente 0 horas luz (oscuridad total. La esporulación se vio favorecida por fotoperiodos de 8 a 16 horas a 560 lux, y presentó un alto desempeño con periodos de 12 horas a 790 lux. La exposición continua a la luz demostró tener un efecto inhibidor sobre la esporulación de P. sparsa. Así mismo, determinó la producción de esporangios con características atípicas, como bajo contenido citoplasmático y menor tamaño.

  15. BIOLOGÍA DE OLIGONYCHUS YOTHERSI (MCGREGOR (ACARI: TETRANYCHIDAE SOBRE AGUACATE PERSEA AMERICANA MILL. CV. LORENA (LAURACEAE

    Directory of Open Access Journals (Sweden)

    Reyes Julian C

    2011-06-01

    Full Text Available Se estudió la biología del ácaro rojo Oligonychus yothersi en condiciones controladas(26 ± 3°C 56 ± 3% HR, sobre hojas maduras de aguacate, Persea americana Mill. cv.Lorena. Las observaciones se realizaron durante una generación del ácaro. La duraciónde todos los estados, a excepción del adulto, fueron los siguientes: huevo 119.06 horas±13.77 (4.96 días; larva 54.09 horas ± 18.48 (2.25 días, protocrisálida 18.22 ± 9.53(0.76 días, protoninfa 50.62 horas ± 13.29 (2.11 días, deutocrisalida 21.66 horas ±7.78 (0.90 días, deutoninfa 62.54 horas ± 12.85 (2.61 días y teliocrisalida 30.79 horas± 13.28 (1.28 días. La duración total de huevo a emergencia de adulto fue estimadaen 344.21 horas (14.34 días. La relación de sexos encontrada fue de 4.8 hembras: 1macho. Los parámetros poblacionales, i.e., longevidad, fecundidad, tasa intrínsecade crecimiento (r m , tiempo de duplicación y tiempo generacional, sugieren un altopotencial reproductivo y de desarrollo del ácaro sobre aguacate cv. Lorena.

  16. Actions of four organic acids in radix isatidis on endotoxin-neutralization investigated by kinetic turbidimetric assay.

    Science.gov (United States)

    Ma, Li; He, Ying-jun; Li, You; Gong, Mu-xin

    2012-06-01

    To investigate anti-endotoxin action of four OAs reacted with endotoxin by the LAL assay with KTA. Using a incubating kinetic tube reader and kinetic turbidimetric assay (KTA), the concentration-response time curve of endotoxin reacted with limulus amebocyte lysate (LAL) at 37 degrees C were obtained and the action of four organic acids (OAs) on it were investigated. The four OAs were benzoic acid, salicylic acid, syringic acid and 2-amino-benzoic acid from Radix isatidis. Meanwhile, the temperature variation caused by endotoxin with the four OAs was studied by the rabbit pyrogen test (RPT). It was showed that a low concentration (1 mg/mL) of the four OAs had a little effect of anti-endotoxin, and when the concentrations of the four OAs were 30 mg/mL, the endotoxin was neutralized completely. The relationships between the concentrations of endotoxin and the OAs were all linear with correlation coefficients of greater than 0.9995, indicating that the four OAs all had strong anti-endotoxin action, while syringic acid had the strongest action among the four OAs with IC50 of 12.84 mg/mL. The investigations of KTA agreed well with the results obtained by means of RPT.

  17. The short-term effects of treatment of chronic periodontitis on circulating levels of endotoxin, C-reactive protein, tumor necrosis factor-alpha, and interleukin-6.

    Science.gov (United States)

    Ide, Mark; Jagdev, Daljit; Coward, Paula Y; Crook, Martin; Barclay, G Robin; Wilson, Ron F

    2004-03-01

    The acute-phase response involves molecules including tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and C-reactive protein (CRP). This study aimed to determine whether subgingival scaling resulted in rapid changes in plasma concentrations of these molecules. Twenty-three non-smoking adults with chronic periodontitis received subgingival scaling for 60 minutes. Venous blood samples were taken at 0, 15, 30, 60, and 120 minutes. TNF-alpha and IL-6 were assayed from all samples and CRP from the baseline and final samples. Lipopolysaccharide (LPS) was assayed at 0, 15, and 30 minutes using limulus lysate assay (LAL) and EndoCAb Ig assays. LPS assays were suggestive of a transient low-grade bacteremia, but changes in LPS approaching significance (P=0.061) were seen with LAL only. There was a significant increase in circulating TNF-alpha (P=0.0387) and IL-6 (Pperiodontal breakdown (P=0.001). There was also a significant correlation between levels of IL-6 and TNF-alpha (Pperiodontitis patients undergoing an episode of subgingival scaling show a significant elevation in circulating TNF-alpha and IL-6. This may account for anecdotal reports of pyrexia following treatment and may be significant in terms of the relationship between periodontal disease, bacteremia, and cardiovascular disease.

  18. Toxic cyanobacteria and cyanotoxins in public hot springs in Saudi Arabia.

    Science.gov (United States)

    Mohamed, Zakaria A

    2008-01-01

    Toxic cyanobacteria are well reported in rivers, lakes and even marine environments, but the toxin production of cyanobacteria in hot springs is largely unexplored. Therefore, the present study investigated the presence of toxic cyanobacteria and cyanotoxins in public hot springs in Saudi Arabia. The results of an enzyme-linked immunosorbent assay (ELISA) revealed that Saudi spring cyanobacterial mats contained microcystins (MCYSTs) at concentrations ranging from 468 to 512.5 microg g(-1). The Limulus amebocyte lystae (LAL) assay detected lipopolysaccharide (LPS) endotoxins in these mats at concentrations ranging from 433.3 to 506.8 EU g(-1). MCYSTs and endotoxins were also detected in spring waters at levels of 5.7 microg l(-1) and 640 EU ml(-1), respectively, exceeding WHO's provisional guideline value for MCYST-LR in drinking-water. High-performance liquid chromatography (HPLC) analysis revealed that only Oscillatoria limosa and Synechococcus lividus can produce MCYSTs with a profile consisting of MCYST-RR and -LR. Based on the LAL assay, 12 out of 17 cyanobacterial species contained LPS at concentrations ranging from 0.93 to 21.06 EU g(-1). However, not all LPS of these species were toxic to mice. This study suggests that the hot springs in the world including Saudi Arabia should be screened for toxic cyanobacteria to avoid the exposure of people recreating and bathing in spring waters to cyanobacterial toxins.

  19. In Vitro Antilisterial Properties of Crude Methanol Extracts of Garcinia kola (Heckel Seeds

    Directory of Open Access Journals (Sweden)

    Dambudzo Penduka

    2012-01-01

    Full Text Available Crude methanol extracts of Garcinia kola (Heckel seeds were screened for their antilisterial activities against 42 Listeria bacteria isolated from wastewater effluents. The extract had activity against 45% of the test bacteria and achieved minimum inhibitory concentrations (MICs ranging between 0.157 and 0.625 mg/mL. The rate of kill of the extract was determined against four representative Listeria species in the study, and the results showed that the highest percentage of bacteria cells were killed after the maximum exposure time of 2 h at the highest concentration of 4×MIC value, with the maximum number of bacteria cells killed being for L. ivanovii (LEL 30 100%, L. monocytogenes (LAL 8 94.686%, L. ivanovii (LEL 18 60.330%, and L. grayi (LAL 15 56.071% We therefore conclude that the nature of inhibition of the crude methanol extracts of Garcinia kola seeds can be either bactericidal or bacteriostatic depending on the target Listeria species and can also differ among same species as evidenced by L. ivanovii strains LEL 30 and LEL 18.

  20. Wolman disease associated with hemophagocytic lymphohistiocytosis: attempts for an explanation.

    Science.gov (United States)

    Taurisano, Roberta; Maiorana, Arianna; De Benedetti, Fabrizio; Dionisi-Vici, Carlo; Boldrini, Renata; Deodato, Federica

    2014-10-01

    The lysosomal acid lipase (LAL) is the enzyme responsible of the hydrolysis of cholesteryl esters and triglycerides within endo-lysosomes. Loss of enzyme activity leads to accumulation of cholesteryl esters and triglycerides in the lysosome of most tissues. The complete deficiency of LAL is responsible of Wolman disease (WD), a severe systemic disease manifesting in the first days of life with vomiting, diarrhea, failure to thrive, hepatosplenomegaly, jaundice, anemia, and thrombocytopenia. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition which may be genetically determined or secondary to infections, malignancies, immune deficiencies, and rheumatologic disorders. So far, some inborn errors of metabolism have been associated with HLH (e.g., lysinuric protein intolerance, Gaucher's disease), and it has been anecdotally described in three WD patients, without any specific pathogenetic hypothesis. Here, we report on a WD patient, showing clear clinical, biochemical, and histological features indicative of HLH. We discuss the pathophysiological role of cholesteryl ester-induced inflammasome activation in macrophages, leading to a secondary HLH. This case indicates that WD can cause secondary HLH and suggests that a careful metabolic workup should be performed when facing to a pediatric patient with HLH.

  1. Evaluation of plasma cholestane-3β,5α,6β-triol and 7-ketocholesterol in inherited disorders related to cholesterol metabolism.

    Science.gov (United States)

    Boenzi, Sara; Deodato, Federica; Taurisano, Roberta; Goffredo, Bianca Maria; Rizzo, Cristiano; Dionisi-Vici, Carlo

    2016-03-01

    Oxysterols are intermediates of cholesterol metabolism and are generated from cholesterol via either enzymatic or nonenzymatic pathways under oxidative stress conditions. Cholestan-3β,5α,6β-triol (C-triol) and 7-ketocholesterol (7-KC) have been proposed as new biomarkers for the diagnosis of Niemann-Pick type C (NP-C) disease, representing an alternative tool to the invasive and time-consuming method of fibroblast filipin test. To test the efficacy of plasma oxysterol determination for the diagnosis of NP-C, we systematically screened oxysterol levels in patients affected by different inherited disorders related with cholesterol metabolism, which included Niemann-Pick type B (NP-B) disease, lysosomal acid lipase (LAL) deficiency, Smith-Lemli-Opitz syndrome (SLOS), congenital familial hypercholesterolemia (FH), and sitosterolemia (SITO). As expected, NP-C patients showed significant increase of both C-triol and 7-KC. Strong increase of both oxysterols was observed in NP-B and less pronounced in LAL deficiency. In SLOS, only 7-KC was markedly increased, whereas in both FH and in SITO, oxysterol concentrations were normal. Interestingly, in NP-C alone, we observed that plasma oxysterols correlate negatively with patient's age and positively with serum total bilirubin, suggesting the potential relationship between oxysterol levels and hepatic disease status. Our results indicate that oxysterols are reliable and sensitive biomarkers of NP-C. Copyright © 2016 by the American Society for Biochemistry and Molecular Biology, Inc.

  2. Evaluation of plasma cholestane-3β,5α,6β-triol and 7-ketocholesterol in inherited disorders related to cholesterol metabolism[S

    Science.gov (United States)

    Boenzi, Sara; Deodato, Federica; Taurisano, Roberta; Goffredo, Bianca Maria; Rizzo, Cristiano; Dionisi-Vici, Carlo

    2016-01-01

    Oxysterols are intermediates of cholesterol metabolism and are generated from cholesterol via either enzymatic or nonenzymatic pathways under oxidative stress conditions. Cholestan-3β,5α,6β-triol (C-triol) and 7-ketocholesterol (7-KC) have been proposed as new biomarkers for the diagnosis of Niemann-Pick type C (NP-C) disease, representing an alternative tool to the invasive and time-consuming method of fibroblast filipin test. To test the efficacy of plasma oxysterol determination for the diagnosis of NP-C, we systematically screened oxysterol levels in patients affected by different inherited disorders related with cholesterol metabolism, which included Niemann-Pick type B (NP-B) disease, lysosomal acid lipase (LAL) deficiency, Smith-Lemli-Opitz syndrome (SLOS), congenital familial hypercholesterolemia (FH), and sitosterolemia (SITO). As expected, NP-C patients showed significant increase of both C-triol and 7-KC. Strong increase of both oxysterols was observed in NP-B and less pronounced in LAL deficiency. In SLOS, only 7-KC was markedly increased, whereas in both FH and in SITO, oxysterol concentrations were normal. Interestingly, in NP-C alone, we observed that plasma oxysterols correlate negatively with patient’s age and positively with serum total bilirubin, suggesting the potential relationship between oxysterol levels and hepatic disease status. Our results indicate that oxysterols are reliable and sensitive biomarkers of NP-C. PMID:26733147

  3. Clustering Batik Images using Fuzzy C-Means Algorithm Based on Log-Average Luminance

    Directory of Open Access Journals (Sweden)

    Ahmad Sanmorino

    2012-06-01

    Full Text Available Batik is a fabric or clothes that are made ​​with a special staining technique called wax-resist dyeing and is one of the cultural heritage which has high artistic value. In order to improve the efficiency and give better semantic to the image, some researchers apply clustering algorithm for managing images before they can be retrieved. Image clustering is a process of grouping images based on their similarity. In this paper we attempt to provide an alternative method of grouping batik image using fuzzy c-means (FCM algorithm based on log-average luminance of the batik. FCM clustering algorithm is an algorithm that works using fuzzy models that allow all data from all cluster members are formed with different degrees of membership between 0 and 1. Log-average luminance (LAL is the average value of the lighting in an image. We can compare different image lighting from one image to another using LAL. From the experiments that have been made, it can be concluded that fuzzy c-means algorithm can be used for batik image clustering based on log-average luminance of each image possessed.

  4. Evaluation of Discrimination Indices Validity for Screening of β-Thalassemia Trait

    Directory of Open Access Journals (Sweden)

    Ahmadi A.

    2009-11-01

    Full Text Available AbstractBackground and Objectives: β-thalassemia trait (β-TT and iron deficiency anemia (IDA are the most common forms of microcytic anemia. Screening of β-thalassemia trait is important for medical counseling before marriage and preventing β-thalassemia major birth results. The most common problem in screening -TT is differentiating it from IDA. The aim of this study was to define the sensitivity, specificity, and predictive values of some discrimination indices for screening of β-TT in a sample of such patients.Methods: A total of 82 patients with microcytic anemia (MCV< 80 fl were selected from Namazi Hospital, Shiraz, Iran, and 9 discrimination indices were calculated for them. The patients were divided intotwo groups: 42 patients with β-TT and 40 patients with IDA. The sensitivity, specificity, positive and negative predictive values and Youden,s index of each discrimination index were calculated for screening β-TT.Results: None of the discrimination indices showed 100% of sensitivity and specificity. But the Shin and Lal index, RDW index and RBC count showed the highest and valuable value for screening β-TT.Conclusion: Some discrimination indices like Shin and Lal index, RDW index and RBC index are valuable indices in screening β-TT.Keywords: Beta- Thalassemia; Anemia, Iron Deficiency.

  5. Solar filament material oscillations and drainage before eruption

    International Nuclear Information System (INIS)

    Bi, Yi; Jiang, Yunchun; Yang, Jiayan; Hong, Junchao; Li, Haidong; Yang, Dan; Yang, Bo

    2014-01-01

    Both large-amplitude longitudinal (LAL) oscillations and material drainage in a solar filament are associated with the flow of material along the filament axis, often followed by an eruption. However, the relationship between these two motions and a subsequent eruption event is poorly understood. We analyze a filament eruption using EUV imaging data captured by the Atmospheric Imaging Array on board the Solar Dynamics Observatory and the Hα images from the Global Oscillation Network Group. Hours before the eruption, the filament was activated, with one of its legs undergoing a slow rising motion. The asymmetric activation inclined the filament relative to the solar surface. After the active phase, LAL oscillations were observed in the inclined filament. The oscillation period increased slightly over time, which may suggest that the magnetic fields supporting the filament evolve to be flatter during the slow rising phase. After the oscillations, a significant amount of filament material was drained toward one filament endpoint, followed immediately by the violent eruption of the filament. The material drainage may further support the change in magnetic topology prior to the eruption. Moreover, we suggest that the filament material drainage could play a role in the transition from a slow to a fast rise of the erupting filament.

  6. Inhibition of lipopolysaccharide induced acute inflammation in lung by chlorination.

    Science.gov (United States)

    Zhang, Jinshan; Xue, Jinling; Xu, Bi; Xie, Jiani; Qiao, Juan; Lu, Yun

    2016-02-13

    Lipopolysaccharide (LPS, also called endotoxin) is a pro-inflammatory constituent of gram negative bacteria and cyanobacteria, which causes a potential health risk in the process of routine urban application of reclaimed water, such as car wash, irrigation, scenic water refilling, etc. Previous studies indicated that the common disinfection treatment, chlorination, has little effect on endotoxin activity removal measured by Limulus amebocyte lysate (LAL) assay. However, in this study, significant decrease of acute inflammatory effects was observed in mouse lung, while LAL assay still presented a moderate increase of endotoxin activity. To explore the possible mechanisms, the nuclear magnetic resonance (NMR) results showed the chlorination happened in alkyl chain of LPS molecules, which could affect the interaction between LPS and LPS-binding protein. Also the size of LPS aggregates was found to drop significantly after treatment, which could be another results of chlorination caused polarity change. In conclusion, our observation demonstrated that chlorination is effective to reduce the LPS induced inflammation in lung, and it is recommended to use health effect-based methods to assess risk removal of water treatment technologies. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Alkali solution extraction of rice residue protein isolates: Influence of alkali concentration on protein functional, structural properties and lysinoalanine formation.

    Science.gov (United States)

    Hou, Furong; Ding, Wenhui; Qu, Wenjuan; Oladejo, Ayobami Olayemi; Xiong, Feng; Zhang, Weiwei; He, Ronghai; Ma, Haile

    2017-03-01

    This study evaluated the nutrient property and safety of the rice residue protein isolates (RRPI) product (extracted by different alkali concentrations) by exploring the protein functional, structural properties and lysinoalanine (LAL) formation. The results showed that with the rising of alkali concentration from 0.03M to 0.15M, the solubility, emulsifying and foaming properties of RRPI increased at first and then descended. When the alkali concentration was greater than 0.03M, the RRPI surface hydrophobicity decreased and the content of thiol and disulfide bond, Lys and Cys significantly reduced. By the analysis of HPLC, the content of LAL rose up from 276.08 to 15,198.07mg/kg and decreased to 1340.98mg/kg crude protein when the alkali concentration increased from 0.03 to 0.09M and until to 0.15M. These results indicated that RRPI alkaline extraction concentration above 0.03M may cause severe nutrient or safety problems of protein. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. 1,000 consecutive cases of laser-assisted liposuction and suction-assisted lipectomy managed with local anesthesia.

    Science.gov (United States)

    Chia, Christopher T; Theodorou, Spero J

    2012-08-01

    Advances in suction-assisted lipectomy (SAL) include improved instrumentation, better understanding of fluid dynamics, and an improved concept of appropriate indications. The tumescent technique uses subcutaneous injection of isotonic fluid containing vasoconstrictive and analgesic agents and is proved to be safe, with low morbidity and mortality rates. Laser-assisted liposuction (LAL) using local infiltration of an anesthetic and no general anesthesia or sedation has been developed, with claims of fat destruction and skin tightening. This study aimed to review 1,000 consecutive cases of LAL and SAL performed with the patient under local anesthesia and to determine whether this represents a safe technique with few complications. During a period of 22 months, 581 consecutive patients (486 females and 95 males) underwent 1,000 LAL/SAL operations, 545 of whom had multiple procedures performed. None of the patients had a body mass index (BMI) higher than 30 kg/m2. The patients ranged in age from 18 to 62 years. The fat aspirate ranged from 50 to 1,400 ml. Patients were given an oral sedative, an antibiotic, and an analgesic. Ringer's lactate solution containing lidocaine and epinephrine was injected into the subcutaneous space. The 1,064-nm and/or 1,320-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser was used for laser lipolysis followed by SAL using standard and/or power-assisted liposuction (PAL) cannulas. The treated areas included the neck, triceps, male breast, midback, flanks, axilla, abdomen, mons pubis, thighs, presacrum, and knees. No patient was administered intravenous sedation or general anesthesia. The average number of areas treated was 1.8, and no major complications or mortalities were observed. There were three burns, two infections, one hematoma, and one seroma. A total of 73 secondary procedures were performed (7.3%). No tertiary procedures were required. For appropriately selected patients, comparable results can be obtained with an excellent

  9. Limiares térmicos para a germinação de conídios de Cercospora sojina em dois regimes luminosos

    Directory of Open Access Journals (Sweden)

    Juliane Nicolodi Camera

    2013-03-01

    Full Text Available O objetivo desse trabalho foi avaliar a germinação de conídios horas, verificou-se que a maior germinação ocorreu na temperatura de Cercospora sojina em diferentes temperaturas com luz contínua de 23,8 ºC, para 6 horas foi de 24,3 ºC, para 9 horas foi de 22,9 ºC e no escuro, visando a determinar os limiares térmicos inferior e e para 12 horas foi de 22,4ºC. Quando as placas foram incubadas superior e a temperatura ótima. Os conídios foram depositados na no escuro, verificou-se que a maior germinação dos conídios para superfície das placas de petri contendo substrato ágar-água. Em o tempo de exposição de 3 horas foi na temperatura de 23,8 ºC, seguida foram incubadas em DBO com luz contínua e no escuro para 6 horas foi de 23,4 ºC, para 9 horas foi de 22,9 ºC e para 12 nas temperaturas (0; 5; 10; 15; 20; 25; 30; 35 e 40 ºC e retiradas horas 22,7 ºC. A temperatura ótima para a germinação de conídios nos tempos de exposição (3, 6, 9 e 12 horas. Para os conídios de na luz contínua foi de 22,4 ºC e no escuro de 23 ºC, sendo o limiar C. sojina submetidos à luz contínua no tempo de exposição de 3 térmico inferior de 0 ºC e o superior de 40 ºC.

  10. A study to assess the prevalence and pattern of substance use among male adolescents in suburban area of Delhi

    Directory of Open Access Journals (Sweden)

    Liza Thankam Daniel

    2017-01-01

    Full Text Available Aim of the Study: To assess the prevalence and pattern of substance use among male adolescents in Sunder Nagari, New Delhi. Materials and Methods: A cross-sectional survey was designed to assess the prevalence and pattern of substance use among male adolescents in New Delhi. One hundred and ten adolescents were conveniently selected from Sunder Nagari, New Delhi. Adolescents aged more than 11 years and able to read and write Hindi or English were included in the study. A structured questionnaire for demographic variables was developed by researchers. To assess the prevalence and pattern of substance use, a structured questionnaire was prepared with the reliability coefficient of 0.94 (test-retest reliability with a content validity index of 0.90 between the experts. Data were collected from the subjects after getting their written consent. Data analyzed using statistical package SPSS version 17.0. The level of significance was set as P < 0.05. Results: The study findings revealed that nearly more than half (55.6% of the male adolescents reported the use of one or more substances in their lifetime. About 44.26% of the adolescents started to use substances before 13 years of age. Most common reason specified by the subjects to take substance were to be liked by friends (57.38%, to feel like an adult (24.6%, and few of them reported: “like the feeling of substances” (13.11% as reason for taking substances. Common substances used by the subjects were any kind of tobacco (77.05%, inhalants (26.23%, and alcohol (11.47%. Most of the subjects were getting substances from their friends (85.25% and only a few (14.75% by themselves. Association analyses revealed that adolescents who studied less than 10th standard reported more usage of any kind of substances than who studied more than 10th standard. More prevalence of substance use was seen among adolescents who were from nuclear family. Subjects who had less than two siblings reported more substance

  11. Monitoring the impact of urban effluents on mineral contents of water and sediments of four sites of the river Ravi, Lahore.

    Science.gov (United States)

    Shakir, Hafiz Abdullah; Qazi, Javed Iqbal; Chaudhry, Abdul Shakoor

    2013-12-01

    We assessed the impact of urban effluents on the concentrations of selected minerals (Cd, Cr, Cu, Fe, Pb, Zn, Mn, Ni, and Hg) in river Ravi before and after its passage through Lahore city. Water and sediment samples were collected from three lowly to highly polluted downstream sites (Shahdera (B), Sunder (C), and Balloki (D)) alongside the least polluted upstream site (Siphon (A)) during high and low river flow seasons. All the mineral concentrations increased up to site C but stabilized at site D, showing some recovery as compared to the third sampling site. The trend of mean mineral concentration was significantly higher during the low than the high flow season at all the sites. The mean Hg concentrations approached 0.14 and 0.12 mg/l at site A which increased (%) up to 107 and 25% at site B, 1,700 and 1,317% at site C, and 1,185 and 1,177% at site D during low and high river flows, respectively. All mineral concentrations were much higher in the sediment than the water samples. Mean Cd (917%), Cr (461%), Cu (300%), Fe (254%), Pb (179%), Zn (170%), Mn (723%), Ni (853%), and Hg (1,699%) concentrations were higher in riverbed sediments sampled from site C in comparison with the sample collected at site A during low flow season. The domestic and industrial discharges from Lahore city have created undesirable water qualities during the low river flow season. As majority of the mineral levels in the river Ravi were higher than the permissible and safe levels, this is of immediate concern for riverine fish consumers and the users of water for recreation and even irrigation. The use of these waters may pose health risks, and therefore, urgent intervention strategies are needed to minimize river water pollution and its impact on fish-consuming communities of this study area and beyond.

  12. Mantle contamination and the Izu-Bonin-Mariana (IBM) 'high-tide mark': evidence for mantle extrusion caused by Tethyan closure

    Science.gov (United States)

    Flower, M. F. J.; Russo, R. M.; Tamaki, K.; Hoang, N.

    2001-04-01

    Western Pacific basins are characterized by three remarkable attributes: (1) complex kinematic histories linked to global-scale plate interactions; (2) DUPAL-like contaminated mantle; and (3) rapid post-Mesozoic rollback of the confining arc-trench systems. The coincidence of slab steepening, extreme arc curvature, and vigorous basin opening associated with the Mariana convergent margin suggests that rollback continues in response to an east-directed mantle 'wind'. Against a backdrop of conflicting kinematic and genetic interpretations we explore the notion that eastward asthenospheric flow driven by diachronous Tethyan closure caused stretching of eastern Eurasia and concomitant opening of western Pacific basins. Marking the eastern boundary of the latter, the Izu-Bonin-Mariana forearc may be regarded as a litho-tectonic 'high-tide mark' comprising igneous and metamorphic products from successive episodes (since ca. 45 Ma.) of arc sundering and backarc basin opening. The forearc also forms an isotopic boundary separating contaminated western Pacific mantle from the N-MORB Pacific Ocean reservoir. While the isotopic composition of western Pacific mantle resembles that feeding Indian Ocean hotspot and spreading systems, its spatial-temporal variation and the presence of subduction barriers to the south appear to preclude northward flow of Indian Ocean mantle and require an endogenous origin for sub-Eurasian contaminated mantle. It is concluded that the extrusion of Tethyan asthenosphere, contaminated by sub-Asian cratonic lithosphere, was a major cause of western Pacific arc rollback and basin opening. The model is consistent with paleomagnetic and geologic evidence supporting independent kinematic histories for constituent parts of the Philippine Sea and Sunda plates although interpretation of these is speculative. Compounded by effects of the Australia-Indonesia collision, late-Tethyan mantle extrusion appears to have produced the largest DUPAL domain in the

  13. The drive to innovation: The privileging of science and technology knowledge production in Canada

    Science.gov (United States)

    Cauchi, Laura

    This dissertation project explored the privileging of knowledge production in science and technology as a Canadian national economic, political and social strategy. The project incorporated the relationship between nation-state knowledge production and how that knowledge is then systematically evaluated, prioritized and validated by systems of health technology assessment (HTA). The entry point into the analysis and this dissertation project was the Scientific Research and Experimental Design (SR&ED) federal tax incentive program as the cornerstone of science and technology knowledge production in Canada. The method of inquiry and analysis examined the submission documents submitted by key stakeholders across the country, representing public, private and academic standpoints, during the public consultation process conducted from 2007 to 2008 and how each of these standpoints is hooked into the public policy interests and institutional structures that produce knowledge in science and technology. Key public meetings, including the public information sessions facilitated by the Canada Revenue Agency and private industry conferences, provided context and guidance regarding the current pervasive public and policy interests that direct and drive the policy debates. Finally, the "Innovation Canada: A Call to Action Review of Federal Support to Research and Development: Expert Panel Report," commonly referred to as "The Jenkins Report" (Jenkins et al., 2011), was critically evaluated as the expected predictor of future public policy changes associated with the SR&ED program and the future implications for the production of knowledge in science and technology. The method of inquiry and analytical lens was a materialist approach that drew on the inspiring frameworks of such scholars as Dorothy Smith, Michel Foucault, Kaushik Sunder Rajan, Melinda Cooper, and, Gilles Deleuze. Ultimately, I strove to illuminate the normalizing force and power of knowledge production in science

  14. Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro.

    Science.gov (United States)

    Jing, N; Marchand, C; Liu, J; Mitra, R; Hogan, M E; Pommier, Y

    2000-07-14

    The G-tetrad-forming oligonucleotides and have been identified as potent inhibitors of human immunodeficiency virus type 1 integrase (HIV-1 IN) activity (Rando, R. F., Ojwang, J., Elbaggari, A., Reyes, G. R., Tinder, R., McGrath, M. S., and Hogan, M. E. (1995) J. Biol. Chem. 270, 1754-1760; Mazumder, A., Neamati, N., Ojwang, J. O., Sunder, S., Rando, R. F., and Pommier, Y. (1996) Biochemistry 35, 13762-13771; Jing, N., and Hogan, M. E. (1998) J. Biol. Chem. 273, 34992-34999). To understand the inhibition of HIV-1 IN activity by the G-quartet inhibitors, we have designed the oligonucleotides and, composed of three and four G-quartets with stem lengths of 19 and 24 A, respectively. The fact that increasing the G-quartet stem length from 15 to 24 A kept inhibition of HIV-1 IN activity unchanged suggests that the binding interaction occurs between a GTGT loop domain of the G-quartet inhibitors and a catalytic site of HIV-1 IN, referred to as a face-to-face interaction. Docking the NMR structure of (Jing and Hogan (1998)) into the x-ray structure of the core domain of HIV-1 IN, HIV-1 IN-(51-209) (Maignan, S., Guilloteau, J.-P. , Qing, Z.-L., Clement-Mella, C., and Mikol, V. (1998) J. Mol. Biol. 282, 359-368), was performed using the GRAMM program. The statistical distributions of hydrogen bonding between HIV-1 IN and were obtained from the analyses of 1000 random docking structures. The docking results show a high probability of interaction between the GTGT loop residues of the G-quartet inhibitors and the catalytic site of HIV-1 IN, in agreement with the experimental observation.

  15. Unzipping of the volcano arc, Japan

    Science.gov (United States)

    Stern, R.J.; Smoot, N.C.; Rubin, M.

    1984-01-01

    A working hypothesis for the recent evolution of the southern Volcano Arc, Japan, is presented which calls upon a northward-progressing sundering of the arc in response to a northward-propagating back-arc basin extensional regime. This model appears to explain several localized and recent changes in the tectonic and magrnatic evolution of the Volcano Arc. Most important among these changes is the unusual composition of Iwo Jima volcanic rocks. This contrasts with normal arc tholeiites typical of the rest of the Izu-Volcano-Mariana and other primitive arcs in having alkaline tendencies, high concentrations of light REE and other incompatible elements, and relatively high silica contents. In spite of such fractionated characteristics, these lavas appear to be very early manifestations of a new volcanic and tectonic cycle in the southern Volcano Arc. These alkaline characteristics and indications of strong regional uplift are consistent with the recent development of an early stage of inter-arc basin rifting in the southern Volcano Arc. New bathymetric data are presented in support of this model which indicate: 1. (1) structural elements of the Mariana Trough extend north to the southern Volcano Arc. 2. (2) both the Mariana Trough and frontal arc shoal rapidly northwards as the Volcano Arc is approached. 3. (3) rugged bathymetry associated with the rifted Mariana Trough is replaced just south of Iwo Jima by the development of a huge dome (50-75 km diameter) centered around Iwo Jima. Such uplifted domes are the immediate precursors of rifts in other environments, and it appears that a similar situation may now exist in the southern Volcano Arc. The present distribution of unrifted Volcano Arc to the north and rifted Mariana Arc to the south is interpreted not as a stable tectonic configuration but as representing a tectonic "snapshot" of an arc in the process of being rifted to form a back-arc basin. ?? 1984.

  16. ¿Qué tan buenos son los patrones del igbc para predecir su comportamiento? Una aplicación con datos de alta frecuencia

    Directory of Open Access Journals (Sweden)

    Julio César Alonso

    2009-07-01

    Full Text Available El objetivo del artículo es evaluar la utilidad de patrones de comportamiento para predecir el comportamiento futuro del Índice General de la Bolsa de Colombia (IGBC. Para tal fin, se emplearon 18 diferentes especificaciones del modelo GARCH-M y datos de alta frecuencia. Los modelos considerados tienen en cuenta el efecto Leverage, el efecto Día de la Semana, el efecto Hora y el efecto Día-Hora. Se evalúan 115 pronósticos para los siguientes 10 minutos para cada uno de los 18 modelos, empleando estadísticas descriptivas y las pruebas de Granger y Newbold (1977 y Diebold y Mariano (1995. Se encuentra que la mejor especificación es la que no tiene en cuenta el efecto día-hora en la media ni en la varianza.

  17. ¿Qué tan buenos son los patrones del igbc para predecir su comportamiento? una aplicación con datos de alta frecuencia

    Directory of Open Access Journals (Sweden)

    Julio César Alonso

    2009-07-01

    Full Text Available El objetivo del artículo es evaluar la utilidad de patrones de comportamiento para predecir el comportamiento futuro del Índice General de la Bolsa de Colombia (IGBC. Para tal fin, se emplearon 18 diferentes especificaciones del modelo GARCH-M y datos de alta frecuencia. Los modelos considerados tienen en cuenta el efecto Leverage, el efecto Día de la Semana, el efecto Hora y el efecto Día-Hora. Se evalúan 115 pronósticos para los siguientes 10 minutos para cada uno de los 18 modelos, empleando estadísticas descriptivas y las pruebas de Granger y Newbold (1977 y Diebold y Mariano (1995. Se encuentra que la mejor especificación es la que no tiene en cuenta el efecto día-hora en la media ni en la varianza.

  18. Qualidade da água e desempenho produtivo da tilápia do Nilo alimentada em diferentes freqüências e períodos por meio de dispensador automático

    OpenAIRE

    Sousa, Rodrigo Morgado Ramalho de [UNESP

    2007-01-01

    O objetivo deste experimento foi avaliar o desempenho da tilápia criada em tanque-rede, provido com dispensador automático de ração, com fornecimento em diferentes freqüências (de hora em hora e de duas em duas horas) e períodos (diurno, noturno e ambos). Foram utilizados dezoito tanques-rede de 1,0 m3, distribuídos em um viveiro de 2000 m2, com profundidade média de dois metros e renovação de água de 5,0 %. As tilápias, com peso inicial de 16,0,0l4,9 g, foram distribuídas nos tanques-rede na...

  19. Supersincronización del crecimiento in vitro del Plasmodium falciparum

    Directory of Open Access Journals (Sweden)

    María Orfa de Rojas

    1987-12-01

    Full Text Available Se logró un crecimiento "Super sincrónico" del parásito Plasmodium falciparum en cultivo, mediante la aplicación de tres tratamientos sucesivos: sorbitol (para destruir formas maduras, Percoll (para concentrar esquizontes y nuevamente sorbitol, después de permitir la reinvación. En esta forma se obtuvo una población de parásitos con un rango de edad entre 0-3 horas, de los cuales el 99.1% fueron esquizontes a las 48 horas de incubación. El desarrollo morfológico del parásito fue completamente normal después del tratamiento y su sincronía se controló estrictamente cada 4 horas en el primer ciclo.

  20. “Sí quiero”: propuesta didáctica de español para fines específicos

    Directory of Open Access Journals (Sweden)

    María Eugenia Brime Bertrand

    2012-08-01

    Full Text Available Esta actividad ha sido creada para trabajar con un grupo de 30 estudiantes italianos de economía del turismo con un nivel A1 del MCRE. El curso tenía una duración de 30 horas divididas en 15 sesiones de dos horas cada una, durante las cuales se trabajaba el lenguaje específico del turismo a través de diferentes situaciones comunicativas. Para ello se creó una WebQuest (a partir de ahora WQ instalada en un Wiki.

  1. “Sí quiero”: propuesta didáctica de español para fines específicos

    Directory of Open Access Journals (Sweden)

    María Eugenia Brime Bertrand

    2012-01-01

    Full Text Available Esta actividad ha sido creada para trabajar con un grupo de 30 estudiantes italianos de economía del turismo con un nivel A1 del MCRE. El curso tenía una duración de 30 horas divididas en 15 sesiones de dos horas cada una, durante las cuales se trabajaba el lenguaje específico del turismo a través de diferentes situaciones comunicativas. Para ello se creó una WebQuest (a partir de ahora WQ instalada en un Wiki.

  2. Análisis ecocardiográfico de la función sistólica del ventrículo izquierdo por médicos no cardiólogos con un dispositivo de bolsillo

    OpenAIRE

    Burgos Medina, César Augusto; Cuartas González, Paula Andrea

    2014-01-01

    Se realizó un estudio transversal, se incluyeron 3 residentes no cardiólogos y se les dio formación básica en ecocardiografía (horas teóricas 22, horas prácticas 65), con recomendaciones de la Sociedad Americana de Ecocardiografia y aportes del aprendizaje basado en problemas, con el desarrollo de competencia técnicas y diagnósticas necesarias, se realizó el análisis de concordancia entre residentes y ecocardiografistas expertos, se recolectaron 122 pacientes hospitalizados que cumplieran con...

  3. El estrés agudo modifica la recuperación y la extinción de la memoria espacial en función de su intensidad

    OpenAIRE

    Cuestas Diana Marcela; Troncoso Julieta

    2007-01-01

    Para evaluar los efectos del estrés agudo por restricción de movimientos sobre la recuperación y la extinción
    de la memoria espacial sin sobreentrenamiento, se utilizaron tres grupos de ratas: control, estrés una hora
    y estrés cuatro horas. Todos los animales fueron entrenados en el laberinto circular de Barnes. El protocolo
    de entrenamiento constaba de ocho ensayos de adquisición (intervalo entre ensayos, IEE; 5 min). Los animales de todos los grupos experime...

  4. En busca de principios gráficos para visualizaciones en la técnica de diseño de Programación Dinámica

    OpenAIRE

    Sáenz Rubio, Belén

    2013-01-01

    Trabajo Fin de Máster ¿ Máster Universitario en Informática Interactiva y Multimedia, Universidad Rey Juan Carlos. Curso académico 2012/2013. Tutor del TFM: Ángel Velázquez Iturbide. Los alumnos de informática, en un primer momento, presentan dificultades a la hora de enfrentarse a los algoritmos o programas, tanto en su diseño como a la hora de entender su comportamiento. Los estudiantes se apoyan en ilustraciones estáticas de libros de texto así como en los dibujos que realizan los prof...

  5. Aplicación del Aprendizaje Basado en Problemas para el estudio de Funciones Reales de Variables Reales

    OpenAIRE

    Varela Lezeta, María Concepción

    2011-01-01

    Duración (en horas): De 21 a 30 horas. Nivel educativo: Grado Se presenta una aplicación de la metodología ABP para el estudio de las funciones reales de dos o mas variables reales. A través de una serie de actividades se guía al alumnado a la comprensión del indicador de aprendizaje que quiera trabajar. Es necesario tener claros los conceptos que se trabajan (continuidad, derivabilidad) para función real de una variables real.

  6. Administración y control de proyectos extendiendo el concepto de indicadores

    OpenAIRE

    Bernardis, Edgardo; Bernardis, Hernán; Montejano, Germán Antonio; Roqué Fourcade, Luis

    2013-01-01

    Hoy en día se manejan extensas cantidades de información, siendo esto un problema complejo a la hora de la toma de decisiones por parte de personas o empresas, particularmente en la industria del software. Para dicho fin, existen diferentes metodologías y herramientas que ayudan a la hora de manejar estas cantidades de información y poder extraer los aspectos más importantes que permiten tomar decisiones respecto del plan que se lleva a cabo. Dichas metodologías y herramientas se basan en con...

  7. Effect of aqueous vegetal extratcts application on larva feeding behavior of Ascia monuste orseis at kale

    OpenAIRE

    Medeiros, Cesar Augusto Manfré; Boiça Júnior, Arlindo Leal

    2005-01-01

    Os efeitos de extratos aquosos de amêndoas de Azadirachta indica e frutos de Sapindus saponaria, aplicados em discos de folhas de couve (Brassica oleracea var. acephala) nas concentrações de 0,0117% e 1,0342% (p/v), respectivamente, foram estudados sobre a alimentação das lagartas de Ascia monuste orseis. Avaliou-se a atratividade e o consumo de área foliar de lagartas de primeiro e terceiro ínstar durante 24 horas, em condições de laboratório (T = 25 ± 2ºC, UR = 60 ± 10% e fotofase = 12 hora...

  8. Aprendizaje de la psicología en Unisocietat

    OpenAIRE

    Latorre Latorre, Ángel; Bisetto Pons, David; Teruel Romero, Jerónima; Frati González, Edit

    2016-01-01

    Unisocietat surge del firme compromiso de la Universitat de València y de las administraciones locales y/o mancomunidades, para ofrecer un servicio de formación continuada a la ciudadanía. Esta formación, va dirigida especialmente a personas de 30 años o más con inquietud para aprender y motivación por la cultura. Se implanta en distintas localidades de la provincia de València a través de un itinerario multidisciplinario de unas 360 horas, distribuidas en tres cursos académicos de 120 horas ...

  9. Matutinidad-vespertinidad, rendimiento académico y variaciones de la atención durante la jornada escolar: control de la influencia de la edad, el tiempo de sueño y la inteligencia

    OpenAIRE

    Escribano Barreno, Cristina

    2012-01-01

    Existen numerosas funciones biológicas y psicológicas que fluctúan a lo largo del día, y esas fluctuaciones no suceden de la misma manera, o si se prefiere, a la misma hora, en todas las personas. Sin embargo, los horarios escolares no están “individualizados” e independientemente de la preferencia por la mañana o la tarde, todos los alumnos deben acudir a clase aproximadamente a la misma hora, lo que parece tener consecuencias para el rendimiento académico del adolescente. La atención es ...

  10. Aprendizaje basado en juegos

    Directory of Open Access Journals (Sweden)

    Marco A. Gómez-Martín

    2012-04-01

    Full Text Available Gracias al incremento de potencia de los ordenadores, gran cantidad de personas dedican horas y horas a aprovechar su aspecto más lúdico, los videojuegos. Por otro lado, existen programas educativos que aprovechan la infinita paciencia de los ordenadores que les hacen capaces de explicar conceptos una y otra vez hasta que los alumnos lo entiendan. En este artículo mostramos qué cosas pueden aportar las aplicaciones de enseñanza a los videojuegos y viceversa. Terminamos describiendo JV2M, como un ejemplo de sistema de aprendizaje basado en juegos.

  11. Fijación de radioyodo en huesos maxilares simulando metástasis en pacientes con Carcinoma Diferenciado de Tiroides (CDT): False- Positive images in patients with Differentiated Thyroid Carcinoma. (DTC)

    OpenAIRE

    Degrossi, O. J.; Gutiérrez, S.; Fadel, A.; Degrossi, E. B.; Valdivieso, M. C.; Balbuena, R. L.; Alak, M. del C.; de Cabrejas, M.

    2008-01-01

    En estudios centellográficos con 131I (CCT) para seguimiento, postablación o tratamiento de pacientes portadores de carcinoma diferenciado de tiroides (CDT) se observan frecuentemente en tiempos precoces áreas de captación del radiotrazador en macizo facial. Estas áreas corresponden, generalmente, a glándulas salivares y extremo anterior de mucosa nasal y se mantienen durante las primeras 48 horas y no son observadas generalmente a las 72 horas. Pero con menor frecuencia se presentan otras qu...

  12. Fijación de radioyodo en huesos maxilares simulando metástasis en pacientes con Carcinoma Diferenciado de Tiroides (CDT): False- Positive images in patients with Differentiated Thyroid Carcinoma. (DTC) Uptake of 131-I in maxillary bones mimicking salivary glands

    OpenAIRE

    O. J. Degrossi; S. Gutiérrez; A. Fadel; E. B. Degrossi; M. C. Valdivieso; R. L. Balbuena; M. del C. Alak; M. de Cabrejas

    2008-01-01

    En estudios centellográficos con 131I (CCT) para seguimiento, postablación o tratamiento de pacientes portadores de carcinoma diferenciado de tiroides (CDT) se observan frecuentemente en tiempos precoces áreas de captación del radiotrazador en macizo facial. Estas áreas corresponden, generalmente, a glándulas salivares y extremo anterior de mucosa nasal y se mantienen durante las primeras 48 horas y no son observadas generalmente a las 72 horas. Pero con menor frecuencia se presentan otras qu...

  13. Avaliação da necessidade de frio em pessegueiro Avaliation of chilling requirement in peach

    Directory of Open Access Journals (Sweden)

    Idemir Citadin

    2002-12-01

    Full Text Available A necessidade de frio de seis cultivares de pessegueiro [Prunus persica (L. Batsch] foi estudada em plantas de um e dois anos, em vasos, submetidas a 150; 300; 450 e 600 horas a 2ºC, e em ramos coletados periodicamente em plantas sob condições de frio natural, a campo. Considerando os resultados obtidos nos dois experimentos, estima-se que a necessidade de frio de 'Precocinho' é em torno de 300 horas a 2ºC, equivalente a 150 unidades de frio (UF pelo modelo de Utah, ou próxima a 200 horas abaixo de 12ºC; para 'Eldorado' e 'Rio grandense', em 450 horas a 2ºC (225 UF ou 365 horas abaixo de 12ºC; para 'BR-1', em 450 horas a 2ºC (225 UF ou 418 horas abaixo de 12ºC; e para 'Planalto' e 'Della Nona', acima de 600 horas a 2ºC (>300 UF. Não foi possível estabelecer a necessidade de frio abaixo de 12ºC para 'Della Nona'.Chilling requirement was investigated in six peach [Prunus persica (L. Batsch] cultivars observing plants in containers, with one or two years, artificially chilled by 150, 300, 450, and 600 hours at 2ºC, and in excised shoots that were periodically taken from the orchard during the rest period. Chilling requirement of 'Precocinho' is 300 hours at 2ºC (around 150 chilling units - CU - using Utah Model or around 200 hours under 12ºC; 'Riograndense' and 'Eldorado' have 450 chilling hours at 2ºC (225 CU or 365 chilling hours under 12ºC; 'BR-1' is 450 chilling requirement at 2ºC (225 CU or 418 chilling hours under 12 ºC; and 'Planalto' and 'Della Nona' are over 600 chilling hours at 2ºC (>300 CU. It was not possible to estimate chilling requirement in 'Della Nona' using temperatures under 12 ºC.

  14. Silla ergonómica

    OpenAIRE

    Alberruche Lucas, Pablo

    2015-01-01

    En este trabajo se va a llevar a cabo un rediseño de una silla de la facultad de la Universidad Carlos III de Madrid en la facultad de Leganés del edificio Sabatini. Con el objetivo de intentar buscar una mejora a la hora de pasar muchas horas en las sillas, antes planteadas, que supone una incomodidad a los alumnos, los cuales, han dejado patente su descontento con los asientos de estas aulas, dada su incomodidad. Se realiza una pequeña reseña histórica sobre la silla y los inicios de la ...

  15. Community Managers: Relaciones Públicas y Comunicación Corporativa en la Red.

    OpenAIRE

    Silva Robles, Carmen

    2017-01-01

    Haciendo una observación general –en el metro, en el autobús, caminando por la calle o en cualquier reunión de amigos– es fácil comprobar que nos encontramos en una nueva era en la que estamos 24 horas on-line ó 24 horas disponibles para comunicarnos con nuestros contactos. Se pueden simultanear conversaciones físicas, con coloquios a través de redes sociales o de sistemas de chats integrados en nuestros teléfonos mó...

  16. Caracterización del consumo de larvas de culícidos (Diptera en dos especies de peces indígenas de la zona central de Argentina

    Directory of Open Access Journals (Sweden)

    Alejo F. Bonifacio

    2014-09-01

    Full Text Available Los mosquitos representan una amenaza para la salud del hombre y de los animales debido a que actúan como vectores de distintas enfermedades. Especies de peces nativos son potenciales candidatos a tenerse en cuenta para control biológico de poblaciones de culícidos. Experiencias de consumo de media hora y de 24 horas por Cnesterodon decemmaculatus (Jenyns, 1842 y Jenynsia multidentata (Jenyns, 1842 se llevaron a cabo con larvas de Culex pipiens (Linnaeus, 1758, midiéndose longitud estándar, ancho de boca y peso en individuos de las dos especies. En ambas pruebas, J. multidentata consumió más C. pipiens que C. decemmaculatus, consumiendo las hembras de esta última especie más que los machos (e igual a ambos sexos de J. multidentata en la prueba de 24 horas de duración. Estos resultados no variaron cuando se compararon tantos consumos absolutos o relativos para las pruebas de media hora, sin embargo cuando se compararon los consumos relativos al peso no se encontraron diferencias entre las especies para las pruebas de 24 horas. Análisis de regresión entre las tasas de consumo versus las variables morfométricas y el peso mostraron poco valor explicativo en las pruebas de media hora de duración, mientras que en las pruebas de 24 horas de duración los análisis de regresión tuvieron un mayor valor explicativo, especialmente con el ancho de la boca. Por último, pruebas de media hora de duración fueron llevadas a cabo exponiendo a hembras de C. decemmaculatus con larvas de C. pipiens y Aedes aegypti (Linnaeus, 1742 observándose una fuerte preferencia por las últimas. Este trabajo permitió evidenciar que las especies de peces en estudio presentan grandes diferencias en las tasas de consumo de C. pipiens en periodos cortos. Estas diferencias se atenuaron cuando las tasas de consumo se prolongaron y hasta llegar a desaparecer cuando el peso se tuvo en cuenta.

  17. Fatores que interferem no sono dos alunos idosos da Universidade da Maturidade (UMA, na cidade de Palmas (TO

    Directory of Open Access Journals (Sweden)

    Núbia Kênia Carneiro Silva

    2015-05-01

    Full Text Available O processo de senescência ocasiona mudanças na quantidade e qualidade do sono; assim, a maioria dos idosos tem queixas relacionadas ao sono, decorrentes de mudanças fisiológicas específicas do processo de envelhecimento, que podem causar distúrbios relacionados ao sono. Objetiva-se verificar quais os fatores que interferem no sono dos idosos alunos da Universidade da Maturidade (UMA, na cidade de Palmas (TO. Trata-se de um estudo descritivo de corte transversal, e de natureza quantitativa. Para o levantamento dos dados, utilizaram-se os instrumentos: Questionário de caracterização socioeconômico, seguido da Escala de Sonolência de Epworth (ESE, e do Índice de Qualidade de Sono de Pittsburgh (PSQI. Os resultados da ESE revelaram que 75% do grupo masculino e 51,85% do feminino apresentaram sonolência diurna excessiva normal com escores <10. As respostas abertas do PSQI, em relação à hora de deitar, mostram que 43,75% dos homens deitavam entre 23 e 24 horas; no grupo das mulheres, 29,63% deitavam entre 21 e 22 horas; quanto ao tempo para dormir, 68,75% dos homens e 62,96% das mulheres demoravam ≤ 15 minutos; em relação à hora de acordar, 75% dos homens e 37,04% das mulheres acordam entre 6 e 7 horas; em relação a quantas horas de sono dormiu por noite, 50% dos homens dormiram entre 7 e 8 horas por noite, e 51,85% das mulheres dormiram ≥ 8 horas por noite. Já no PSQI global, 56,25% dos homens possuem uma boa qualidade do sono, enquanto 66,67% das mulheres apresentaram má qualidade do sono, apesar de terem uma maior eficiência relacionada ao sono. Os resultados mostraram que os homens tiveram uma boa qualidade do sono e as mulheres tiveram uma má qualidade do sono.  

  18. Eficacia del alfabeto lloje yupanki en la enseñanza – aprendizaje del quechua como segunda lengua en el I.S.P.P. Mercedes Cabello de Carbonera de Moquegua – 2011

    OpenAIRE

    Gutiérrez Castro, Franklin

    2015-01-01

    La investigación titulada EFICACIA DEL ALFABETO LLOJE YUPANKI EN LA ENSEÑANZA – APRENDIZAJE DEL QUECHUA COMO SEGUNDA LENGUA EN EL I.S.P.P. MERCEDES CABELLO DE CARBONERA DE MOQUEGUA – 2011da a conocer la experiencia educativa realizada en esta institución en el año 2008, durante los meses de setiembre y octubre. Con un total de ochenta horas pedagógicas: dos horas diarias. El objetivo es demostrar que el Alfabeto Lloje Yupanki es eficaz para el proceso de enseñanza-aprendizaje del quechua co...

  19. Orientación hacia el consumo abusivo de televisión en la infancia

    OpenAIRE

    Toscano Cruz, María O

    2005-01-01

    Nuestra comunicación tiene como objetivo principal orientar a los infantes a la hora de ver la televisión. Inevitablemente, la tele se ha convertido en algo habitual e imprescindible en la mayoría de los hogares. Los niños se habitúan a ella desde muy temprana edad, y a veces pasan demasiadas horas frente a ella. ¿Puede perjudicarles verla cuando son pequeños? Desde luego, en muchos casos es un instrumento altamente educativo. Muchos programas infantiles son auténticas clases que ...

  20. EFECTO DIURÉTICO DE LAS HOJAS DE MAYTENUS MACROCARPA “CHUCHUHUASI” EN RATAS ALBINAS

    OpenAIRE

    Fanny Bastidas Garcia; Juan Jesús Huaccho Rojas; Javier Chambi Torres; Antonio Padilla Alexander; Luis Aguirre Tipismana; Alberto Salazar Granara; Benjamín Castañeda Castañeda

    2016-01-01

    Objetivo: Evaluar la actividad diurética del extracto acuoso obtenido a partir de la hojas del Maytenus macrocarpa “Chuchuhuasi” en ratas albinas. Material y Métodos: Se utilizaron 68 ratas albinas machos, con pesos medios de 250 g, se empleó el Método de Lipschitz, donde se registró el volumen de orina por hora y total a la sexta hora. Los grupos experimentales fueron: Control (suero fisiológico al 0.9%), chuchuhuasi 1 (250mg/kg), chuchuhuasi 2 (500mg/kg), chuchuhuasi 3 (750mg/kg), hojas de ...

  1. Influencia del cobre en la transformación de fase de la aleación Zn - 22 % p Al, durante la homogenización

    OpenAIRE

    Rangel Lara, S.; Bernal, J. L.; Ita de la Torre, A. de

    2011-01-01

    Las aleaciones fueron producidas por fundición y enfriadas en aire quieto a temperatura ambiente, la microestructura dendrítica fue analizada en un trabajo anterior [1]. Muestras de las aleaciones obtenidas fueron sometidas a un tratamiento de homogenización a 375 °C por 120 horas, se observó la modificación de la microestructura a 60, 100 y 120 horas en las aleaciones Zn - 22 % p Al y Zn - 22 % p Al - 2 % p Cu. Las fases presentes en las aleaciones se identificaron por microscopia óptica. Se...

  2. Avaliação de dois esquemas de manejo da hiperbilirrubinemia em recém-nascidos com peso menor que 2.000 g

    OpenAIRE

    Leite,Maria das Graças C.; Facchini,Fernando P.

    2004-01-01

    OBJETIVO: Avaliar o uso de dois esquemas de fototerapia na hiperbilirrubinemia de recém-nascidos com peso menor que 2.000 g. MÉTODOS: Foram estudados 81 recém-nascidos com peso de nascimento menor que 2.000 g, divididos em dois grupos: "precoce", que iniciou fototerapia com 12 horas de vida e foi tratado por pelo menos 96 horas, e "tardio", que recebeu fototerapia quando a bilirrubina transcutânea atingia 8 mg/dl, sendo retirada quando caísse para 5 mg/dl. Foi analisada a manutenção dos nívei...

  3. Oscar Wilde como artesano: la mediación de la identidad a través de los objetos en "The picture of Dorian Gray" y "The importance of being Earnest"

    OpenAIRE

    Zubieta Jarén, Bárbara

    2016-01-01

    Uno de los aspectos más documentados a la hora de estudiar las obras de Óscar Wilde en profundidad ha sido el concepto de máscara u ocultación. Este concepto fue tratado a su vez por el propio escritor en su ensayo titulado The Truth of Masks (1891), donde analiza, entre otras cosas, la puesta en escena y los objetos que aparecen a la hora de llevar a cabo la representación de las obras de teatro de Shakespeare. Por otra parte, no es necesario señalar que Wilde es harto reconocido por su gust...

  4. Rabdomiolisis y ampollas del coma debido a una poliintoxicación aguda.

    Directory of Open Access Journals (Sweden)

    Margarita Carnero Fernández

    2012-12-01

    Full Text Available Mujer de 35 años, consumidora de alcohol, cocaína y neurolépticos. Ingresa en el hospital en situación de coma, con respuesta a estímulos dolorosos, tras intento de autolisis (ingesta de 12 comprimidos de amoxicilina, 60 de quetiapina, 500 cc de aguardiente, 2 cervezas y cocaína no cuantificada en las horas previas. En la piel se apreciaban placas eritematosas, edematosas, bien delimitadas en cadera, dorso de articulaciones interfalángicas y pies, que en pocas horas evolucionaron formando ampollas tensas de contenido claro.

  5. Alta precoz postparto. Evaluación de las complicaciones maternas y neonatales; repercusión en la ansiedad materna

    OpenAIRE

    Goyeneche Lasaga, Leire

    2014-01-01

    246 p. Ensayo clínico controlado aleatorizado simple ciego, sin medicamento, fase IV, unicéntrico donde se comparó el alta precoz a las 24 horas del parto y una visita hospitalaria a las 48h del alta, con el alta habitual a las 48-72 horas. Para ello se incluyeron un total de 416 mujeres sanas y mayores de edad que habían dado a luz por vía vaginal a un RN único, sano y a término entre el 1 de Octubre del 2012 y el 19 de Septiembre del 2013 en el Hospital Universitario Donostia; 208 fueron...

  6. Influência da idade do hospedeiro e da aprendizagem no comportamento quimiotáxico e no parasitismo de Trichogramma pretiosum

    Directory of Open Access Journals (Sweden)

    Camila C. Vargas

    Full Text Available RESUMO Trichogramma pretiosum Riley, 1879 mantido em ovos de Ephestia kuehniella Zeller, 1879, tem sido utilizado no controle biológico de Spodoptera frugiperda (J. E. Smith, 1797. No entanto, fatores como idade do hospedeiro e experiência prévia, podem influenciar o parasitismo e o comportamento do parasitoide. Esse estudo avaliou a influência da idade dos ovos e da experiência em ovos e extrato de ovos de S. frugiperda no comportamento quimiotáxico e no parasitismo de T. pretiosum. Ovos de S. frugiperda com 24, 48 e 72 horas, foram expostos a fêmeas de T. pretiosum. Também foi avaliado o tempo de experiência do parasitoide, no mesmo hospedeiro, por 1, 3, 4, 5, 6 e 24 horas, assim como, seu tempo de exposição (1, 2, 3 e 24 horas. As respostas quimiotáxicas de T. pretiosum (experiente e não experiente em extrato de ovos de S. frugiperda foram observadas em olfatômetro tipo Y. As taxas de parasitismo foram registradas em teste de escolha, com insetos experientes e inexperientes com ovos e extrato de ovos de S. frugiperda. O parasitismo em S. frugiperda foi significativamente maior em ovos com 24 horas de idade. Fêmeas inexperientes e experientes por 1, 3 e 4 horas, apresentaram uma menor taxa de parasitismo, quando comparadas a fêmeas expostas por 5, 6 e 24 horas. Não houve diferença de parasitismo em fêmeas expostas por 2, 3 e 24 horas, comparadas às expostas por uma hora. Fêmeas experientes foram mais atraídas ao extrato de ovos de S. frugiperda, do que ao controle (hexano. A porcentagem de parasitismo, em fêmeas inexperientes, foi maior em ovos de E. kuehniella (hospedeiro de origem, no entanto, o mesmo resultado não foi observado em fêmeas experientes.

  7. Ciencias Experimentales en el aula de Educación Infantil

    OpenAIRE

    Zamalloa Echevarría, Teresa

    2013-01-01

    Duración (en horas): Más de 50 horas, Destinatario: Estudiante Mediante la metodología de ABP el alumnado de tercer curso del grado de Educación infantil elaborará propuestas didácticas en grupos para el estudio de los contenidos de ciencias experimentales empleando diferentes estrategias y recursos didácticos para la enseñanza/aprendizaje del medio físico y natural en Educación Infantil.

  8. Lógica en la toma de decisiones de inversión en el sector de extracción de petróleo y gas natural

    OpenAIRE

    Mendieta Serna, Diego Andres

    2015-01-01

    Este documento se centra en la presentación de información y análisis de la misma a la hora de establecer la manera en que empresas del sector de extracción de gas natural y generación de energía a base de dicho recurso, toman decisiones en cuanto a inversión, centrándose en la lógica que usan a la hora de emprender este proceso. Esto debido a la constante necesidad de establecer procesos que permitan tomar decisiones más acertadas, incluyendo todas las herramientas posibles para tal fin. ...

  9. Efecto biocida del «barbasco» Lonchocarpus utilis (Smith,1930 como regulador de larvas de mosquitos

    Directory of Open Access Journals (Sweden)

    Carlos Mariños

    2013-06-01

    Full Text Available Se realizaron 7 bioensayos de laboratorio para evaluar la capacidad biocida de Lonchocarpus utilis (Smith,1930 «barbasco» sobre 7000 larvas de tercer y cuarto estadio de Anopheles benarrochi (Gabaldón, 1941, vector primario de malaria, en Yurimaguas y Loreto. La actividad biocida fue determinada con diferentes calidades de agua. Se procesaron las raíces frescas de L. utilis siguiendo el procedimiento utilizado por Vílchez (1993, obteniéndose como producto final un polvo fino que contiene como principio activo la rotenona. La actividad biocida, se midió con 5 dosis de polvo de la raíz diluida en agua destilada: 6,25; 3,1; 2,1; 1,0 y 0,15 g/L. Se utilizó 1 mL del homogenizado como inóculo por dosis. Para determinar la eficacia y susceptibilidad se realizaron lecturas cada hora hasta las 24 horas después del tratamiento. A las 12 horas postratamiento, las dosis de 6,25 y 3,1 g/L, mostraron 98 y 89 % de mortalidad larvaria cuando se utilizó agua destilada y 86 % y 82 % cuando se utilizó agua de criadero. A las 24 horas la mortalidad alcanzó el 99 y 94 % usando agua destilada y con agua de criadero fue 93 y 90 %. A las 6 horas de exposición con agua destilada, la dosis letal media (DL50 fue de 0,63 g/L y la dosis letal noventa (DL90 fue de 12,44 g/L; mientras a las 12 horas la DL50 fue de 0,48 g/L y la DL90 7,23 g/L. Utilizando agua de criadero a las 6 horas la DL50 fue de 1,36 g/L y la DL90 fue de 27,58 g/L; mientras que a las 12 horas la DL50 fue de 0,83 g/L y la DL90 fue de 9,83 g/L del extracto crudo de L utilis. Los resultados permitieron comprobar la efectividad del polvo de raíz de Lonchocarpus utilis sobre larvas de A. benarrochi como potencial biocida y que su acción está influenciada por la calidad del agua y la dosis de aplicación.

  10. Interações Medicamentosas Potenciais em Pacientes de Unidades de Terapia Intensiva

    OpenAIRE

    Liliana Batista Vieira; Adriano Max Moreira Reis; Rhanna Emanuela Fontenele Lima de Carvalho; Leila Márcia Pereira de Faria; Silvia Helena de Bortoli Cassiani

    2012-01-01

    O objetivo do estudo é determinar a frequência de interações fármaco-fármaco em prescrições de pacientes internados em unidades de terapia intensiva e analisar os fatores associados relativos à farmacoterapia e ao paciente. O estudo descritivo transversal foi realizado em dois hospitais de ensino da região centro oeste do Brasil. As interações medicamentosas potenciais foram identificadas nas prescrições do primeiro dia (24 horas) e do quinto dia (120 horas) de interna...

  11. Nuevos tiempos para la comunicaci??n, "branded content" frente a otras tendencias = New times for communication, branded content against other trends

    OpenAIRE

    Carrizo Rey, Vanessa

    2017-01-01

    La manera de comunicarnos entre las personas ha cambiado radicalmente respecto al pasado siglo. Las nuevas tecnolog??as de la informaci??n y comunicaci??n han irrumpido en nuestras vidas de manera que si echamos la vista atr??s apenas 10 a??os, nos daremos cuenta que nada es lo mismo a la hora de comunicarnos con otras personas, con las empresas e incluso en nuestra vida cotidiana como por ejemplo a la hora de hacer la compra o ver la televisi??n, nada es igual. En este trabajo, se hablar?? d...

  12. Diseño, creación y explotación de una base de datos en el ámbito de la gestión empresarial

    OpenAIRE

    Urkola Carrera, Leire; Aldaz Odriozola, Leire; Buenestado Simón, David

    2015-01-01

    Duración (en horas): Más de 50 horas Destinatario: Estudiante y Docente En este recurso se incluyen el cuaderno del docente y del estudiante resultantes de la experiencia de la aplicación de la metodología de Aprendizaje Basado en Proyectos en el ámbito de la asignatura de Sistemas Informáticos de Gestión Empresarial, de cuarto curso del Grado de Administración y Dirección de Empresas impartido en la Escuela Universitaria de Estudios Empresariales de Donostia-San Sebastián. S...

  13. Obtención y evaluación de taninos provenientes del alquitrán de Hulla

    Directory of Open Access Journals (Sweden)

    Inés Ballesteros

    2009-06-01

    Full Text Available Se muestra la posibilidad de obtener taninos sintéticos a partir de la mezcla de fenoles obtenida por destilación del extracto fenólico proveniente de alquitranes de coquización.Las mejores resinas sulfonadas (taninos fueron obtenidas por condensación de formaldehído-fenoles iniciales en una relación molar de 0.6:1.0, durante cuatro horas, y subsiguiente sulfonación en una relación molar de ácido sulfúrico-fenoles iniciales de 0.75:1.00 ó 0.50:1.00, durante dos horas.

  14. Atlas de experiencias innovadoras en educación física

    OpenAIRE

    Garay Ibáñez de Elejalde, Ana Beatriz

    2012-01-01

    Duración (en horas): Más de 50 horas. Destinatario: Estudiante y Docente En la asignatura "Educación de la actividad física y deporte" de 2º curso del grado de en Ciencias de la Actividad Física y el Deporte durante el curso 2011-12 se desarrollo un proyecto titulado "Atlas de experiencias innovadoras en educación física". Los estudiantes eligieron un área temática concreta para trabajar en grupo una parte del proyecto y contribuir entre todos a la elaboración final del atlas. Las temát...

  15. ENSEÑAR BIOÉTICA A ESTUDIANTES DE MEDICINA MEDIANTE EL APRENDIZAJE BASADO EN PROBLEMAS (ABP)

    OpenAIRE

    JOAQUIM BOSCH-BARRERA; HUGO C. BRICEÑO GARCÍA; DOLORS CAPELLÀ; CARMEN DE CASTRO VILA; RAMON FARRÉS; ANNA QUINTANAS; JOSEP RAMIS; ROSA ROCA; JOAN BRUNET

    2015-01-01

    Se describe la implantación de la asignatura de Bioética en una Facultad de Medicina con el objetivo de dotar a los 73 alumnos de quinto curso de competencias para manejar conflictos éticos en su práctica profesional. El método docente utilizado principalmente fue el aprendizaje basado en problemas. Se describen las competencias y objetivos docentes marcados. El diseño de la asignatura consistió en un seminario teórico (2 horas), un taller práctico (2 horas), cuatro casos de aprendizaje basad...

  16. Ganar el pan con el sudor de la frente: el insumo de trabajo en la producción de trigo

    OpenAIRE

    Frank, Rodolfo G.

    2000-01-01

    La mecanización, el mejoramiento genético, la aplicación de agroquímicos y modificaciones de la técnica de cultivo han sido factores decisivos en el aumento de la productividad del trabajo agrícola. Esto se manifiesta en el largo plazo a través de una reducción en el insumo de trabajo por hectárea (horas-hombre/ha) y correlativamente en un aumento de la productividad del trabajo (cantidad de producto/hora-hombre). Empíricamente, esto es un hecho bien conocido. Sin embargo, muy poco ...

  17. ¿En qué idioma hablan las empresas? Proyecto de la asignatura de Introducción a la Contabilidad

    OpenAIRE

    Espinosa Pike, Marcela

    2011-01-01

    Duración (en horas): Más de 50 horas. Nivel educativo: Grado Este proyecto consiste en elaborar la documentación contable correspondiente a una empresa virtual creada por los estudiantes en grupos de 3 o 4 personas. Se trata de acercar el lenguaje de los negocios al alumno mediante una metodología activa de enseñanza, el aprendizaje basado en proyectos, de forma que se acerca la realidad al estudiante, se potencia el trabajo autónomo y cooperativo. Este proceso de enseñanza-aprendizaje,...

  18. Metabolismo posprandial en adultos mayores normales de nivel del mar

    Directory of Open Access Journals (Sweden)

    Fausto Garmendia

    2003-06-01

    Full Text Available Objetivo: Determinar las modificaciones normales del metabolismo después de la ingestión de alimentos. Material y Métodos: Se ha estudiado a 33 personas de ambos géneros, adultos mayores, de nivel del mar, tanto en ayunas como después de la ingesta de una mezcla alimenticia consistente en 730 kcal, con 55,4% de grasas, 37,2% de hidratos de carbono y 7,4% de proteínas. Se ha medido el perfil metabólico en ayunas y luego de la ingesta alimentaria, la glucosa, triglicérido (Tg, ácidos grasos no esterificados (AGNE, insulina por métodos convencionales hasta la 6a hora; se ha calculado las concentraciones de colesterol LDL y VLDL utilizando la fórmula de Friedewald; el colesterol no-HDL, mediante la sustracción del valor del colesterol HDL al valor de colesterol total (CT. Resultados: La glicemia se elevó discretamente, regresando a valores basales a la 2a hora; la insulinemia se incrementó durante 4 horas; los triglicéridos comenzaron a elevarse en sangre a partir de la 2a hora y llegaron al máximo a la 4a hora, para luego iniciar el descenso no completo en la 6a hora. Los AGNE disminuyeron a partir de los 30 minutos, llegando al máximo de caída a las 2 horas; luego se apreció un rebote máximo a la 6a hora, inclusive mayor al valor basal. Conclusiones: Estos resultados demuestran que no es suficiente obtener información del metabolismo intermediario en ayunas, sino que el estudio posprandial permite mayor información. Es la primera vez en nuestro país que se obtiene información sobre el metabolismo intermediario en fase posprandial en una muestra de la población normal que se encuentra en una edad de mayor riesgo cardiovascular.

  19. Dos nuevos registros de Lutzomyia (Diptera: Psychodidae) para el Departamento de Risaralda, Colombia

    OpenAIRE

    BEJARANO, EDUAR ELÍAS; SIERRA, DIANA; VÉLEZ, IVÁN DARÍO

    2007-01-01

    Se registran por primera vez para el departamento de Risaralda, Colombia, dos especies de flebotomíneos pertenecientes al género Lutzomyia : Lutzomyia atroclavata y Lutzomyia sp serie townsendi . Los especimenes de L. atroclavata se obtuvieron con una trampa de luz tipo CDC actividad entre las 18:00 y las 06:00 horas, mientras que los de Lutzomyia serie townsendi se coleccionaron usando cebo humano entre las 18:00 y las 22:00 horas. Se describen las principales características diagnósticas mo...

  20. Laser-assisted lipolysis for arm contouring in Teimourian grades I and II: a prospective study of 45 patients.

    Science.gov (United States)

    Leclère, Franck Marie; Alcolea, Justo M; Vogt, Peter; Moreno-Moraga, Javier; Mordon, Serge; Casoli, Vincent; Trelles, Mario A

    2015-04-01

    Upper arm deformities secondary to weight loss or senile elastosis have led to an increased demand for aesthetic contouring procedures. We conducted this study to objectively assess if, in Teimourian low-grade upper arm remodelling, one session of laser-assisted lypolisis (LAL) could result in full patient satisfaction. Between 2011 and 2013, 45 patients were treated for unsightly fat arm Teimourian grade I (15 patients), grade IIa (15 patients) and grade IIb (15 patients) with one session of LAL. The laser used in this study was a 1470-nm diode laser (Alma Lasers, Cesarea, Israel) with the following parameters: continuous mode, 15 W power and transmission through a 600-μm optical fibre. Previous mathematical modelling suggested that 0.1 kJ was required in order to destroy 1 ml of fat. Treatment parameters and adverse effects were recorded.The arm circumference and skin pinch measurements were assessed pre and postoperatively. Patients were asked to file a satisfaction questionnaire. Pain during the anaesthesia and discomfort after the procedure were minimal. Complications included prolonged oedema in 11 patients. The average arm circumference decreased by 4.9 ± 0.4 cm in the right arm (p < 0.01) and 4.7 ± 0.5 cm in the left arm (p < 0.01) in grade I patients, 5.5 ± 0.6 cm in the right arm (p < 0.01) and 5.2 ± 0.5 cm in the left arm (p < 0.01) in grade IIa patients and 5.4 ± 0.5 cm in the right arm (p < 0.01) and 5.3 ± 0.5 cm in the left arm (p < 0.01) in grade IIB patients. The skin tightening effect was confirmed by the reduction of the skin calliper measurements in all three groups. Overall mean opinion of treatment was high for both patients and investigators. Of the 45 patients, all but one would recommend this treatment. A single session of LAL in upper arm remodelling for Teimourian grades I to IIb is a safe and reproducible technique. The procedure allows reduction in the amount of adipose deposits