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Sample records for suchnek milan komrek

  1. The water footprint of Milan.

    Science.gov (United States)

    Vanham, D; Bidoglio, G

    2014-01-01

    This study quantifies the water footprint of consumption (WFcons) and production (WFprod) of Milan. The current WFcons amounts to 6,139 l/cap/d (a volume of 2.93 km(3) annually), of which 52 l/cap/d (1%) is attributed to domestic water, 448 l/cap/d (7%) to the consumption of industrial products and 5,639 l/cap/d (92%) to the consumption of agricultural products. The WFprod is 52 l/cap/d. Milan is thus a net virtual water importer, predominantly through the import of agricultural products. These are produced outside city borders, both in Italy and abroad. This shows the dependency of city dwellers on water resources from other river basins. In addition, the WFcons for a healthy diet (based on Mediterranean Food-Based Dietary Guidelines) and a vegetarian diet are analysed. The current Milanese diet consists of too much sugar, crop oils, meat, animal fats, milk and milk products and not enough cereals, rice, potatoes, vegetables and fruit. The latter two diets result in substantial WFcons reductions: -29% (to 4,339 l/cap/d) for a healthy diet and -41% (to 3,631 l/cap/d) for a vegetarian diet. Indeed, a lot of water could be saved by Milan citizens through a change in their diet. A sustainable city should account for its impacts beyond its borders.

  2. The Belgian participation in the Milan Triennials

    NARCIS (Netherlands)

    Floré, F.M.W.

    2012-01-01

    The Milan Triennials were a series of international exhibitions on design, fine arts, architecture and urban planning. Their history dates back to 1923 and includes several historical episodes. Since the beginning Belgium was a regular participant in the Milan Triennials. This paper discusses the

  3. Stones used in Milan architecture

    Directory of Open Access Journals (Sweden)

    Folli, Luisa

    2008-06-01

    Full Text Available The city of Milan lies in a plain with clayey soil well suited to brick-making, but no stone deposits. An ample supply of stone is available, however, in the surrounding hills and mountains, which are connected to the city via both natural and artificial waterways. The types of stone used since Roman times include: granite, marble and gneiss from Ossola Valley; dolomite from Lake Maggiore; detrital limestone from Ceresio Valley; sandstone from the Brianza Hills; black limestone and marble from Lake Como; and conglomerate and sandstone from the Adda River basin. Traditionally, the chief uses have been dimension stone (all stones, column shafts (granite, slabs (marble, moulding (dolomite, limestone and ornamental (marble, dolomite, limestone.La ciudad de Milán se encuentra en una llanura de suelo arcilloso adecuado para la fabricación de ladrillos pero en la cual no hay yacimientos de rocas. No obstante, en las colinas y montañas circundantes, que están comunicadas con la ciudad mediante vías navegables naturales y artificiales, sí existe una abundante cantidad de piedra. Entre los tipos de piedra utilizados desde la época de los romanos se encuentran granitos, mármoles y gneises del valle de Ossola, dolomías del lago Mayor, calizas detríticas del valle de Ceresio (Lugano, areniscas de las colinas de la Brianza, calizas negras y mármoles del lago Como y conglomerados y areniscas de la cuenca del río Adda. Tradicionalmente, los principales usos han sido la piedra de fábrica (todas ellas, fustes de columnas (granito, losas (mármol, molduras (dolomía, caliza y ornamental (mármol, dolomía, caliza.

  4. Milan in the age of global contract.

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    Paolo Perulli

    2014-12-01

    Full Text Available Milan is not only the golden location of the fashion and design industries as well as hightech research centres. What is peculiar about Milan, compared to London or Paris, is the contradiction between high density growth (made in the past by industry and the working class, today by finance and the creative class, and low polity. Milan is based on an external source of power corresponding to a weak nation-state. The local élites have been only partially able to negotiate with the central government. The past and recent history of Milan is one of fragmented urban expansion and limited vision. Here the urban contract is based on the (historically variable social relationships and compromises between these main axial systems: infrastructures, knowledge, and creative industry. The first is representative of heavy capitalist and financial interests; the second is the expression of the intellectual capital of the city; the third has the flavour of the new emerging forces of the creative class. Analysing also some other Milan’s features it is clear that the urban contract is made of both local and global players in an asymmetric game.

  5. Epitafos Logos: Milan Mráz

    Czech Academy of Sciences Publication Activity Database

    Boháček, Kryštof

    2011-01-01

    Roč. 59, č. 1 (2011), s. 136-138 ISSN 0015-1831 Institutional research plan: CEZ:AV0Z90090514 Keywords : Milan Mráz * Aristotle * Philosophical Institute of the Czech Academy of Sciences Subject RIV: AA - Philosophy ; Religion

  6. Evolution of Milan microclimate in XX century

    International Nuclear Information System (INIS)

    Schieroni, A.

    1993-01-01

    Within the framework of studies to correlate the use of fossil fuels with urban area thermal pollution, this article examines the local microclimate of Milan, describing the main features of the so-called 'heat island' phenomenon and analyzing the evolution of ambient temperatures. Two different kinds of data on urban temperatures were employed: the hourly measurements taken by the Multinational Presidium for Hygiene and Prevention, run by the Local Sanitary Unit No. 75 of Milan, in the period ranging from 1985 to 1990, and the maximum and minimum daily values referring to the period between 1909 and 1991 (data supplied by the Meteorologic Observatory of Brera-Duomo). The standard year, worked out in the framework of the C. N. R. (National Research Centre) Finalized Energy Project and referring to the meteorological station of Linate Airport, was employed in order to highlight the difference between the thermal behaviour of the urban and the extra-urban area

  7. Milan's 1879 and 1882 gold coins

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    Pantelić Svetlana

    2014-01-01

    Full Text Available Following the exhausting wars against Turkey, Prince Milan Obrenović decided to mint larger denominations of silver and gold coins. The decision on minting these coins was explained by the fact that for the purpose of foreign payments, the expensive foreign money will no longer have to be purchased, given that the Serbian money will be recognized at its nominal value outside Serbia as well. The Law on the Serbian National Money confirmed by Prince Milan on December 10th 1878 introduced new types of metal coins into the monetary system of Serbia: 10 and 20 dinars in gold, 5 dinars in silver, and 2 paras in copper. All these coins were minted in 1879, except for the 10-dinar gold coin, minted when Prince Milan became the King, bearing the inscription of 1882. There were only 50,000 pieces of the 20-dinar gold coins minted, and it was legal tender in the Principality and Kingdom of Serbia, as well as in the Kingdom of Serbs, Croats and Slovenes, and in the Kingdom of Yugoslavia, for full 52 years. In 1882 there were 500,000 pieces of 10-dinar gold coins and 200,000 pieces of 20-dinar gold coins minted. They were named Milandors, and were used as official legal tender until June 28th 1931.

  8. Zemřel JUDr. Milan Princ (1926-2016)

    Czech Academy of Sciences Publication Activity Database

    Nechvátal, Bořivoj; Šlesingerová, Lada

    2016-01-01

    Roč. 76, č. 5 (2016), s. 554-556 ISSN 1210-5538 Institutional support: RVO:67985912 Keywords : Milan Princ * archaeology * historic preservation * obituary * personal bibliography Subject RIV: AC - Archeology, Anthropology, Ethnology

  9. „Diderot miloval mystifikace“, a co Milan Kundera?

    Czech Academy of Sciences Publication Activity Database

    Jungmannová, Lenka

    2017-01-01

    Roč. 65, č. 2 (2017), s. 235-256 ISSN 0009-0468 Institutional support: RVO:68378068 Keywords : Czech drama * Kundera, Milan * Steigerwald, Karel Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  10. Milan Kundera poeediparukaga faun / Kärt Hellerma

    Index Scriptorium Estoniae

    Hellerma, Kärt, 1956-

    1996-01-01

    Arvustus: Kundera, Milan. Surematus. Tln. : Monokkel, 1995. Ilmunud ka kogumikus: Hellerma, Kärt. Kohanenud kirjandus : valik kirjanduskriitikat 1987-2006. Eesti Keele Sihtasutus : Tallinn, 2006. Lk. 176-179

  11. Interpersonal Control in Structural and Milan Systemic Family Therapy.

    Science.gov (United States)

    Friedlander, Myrna L.; And Others

    1991-01-01

    Compared structural and Milan systemic approaches to determine extent to which major proponents behave in ways that are consistent with theory. Focused on interpersonal control dynamics between therapist and family system. Findings from three published transcripts of each treatment were generally congruent with theory and reflected hypothesized…

  12. Building Techniques and Materials in Ancient and Medieval Milan

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    Paola Greppi

    2015-06-01

    Full Text Available The city of Milan preserve an amazing historical and architectural heritage, consisting of a high number of ancient churches, in most cases built to the origins of Christianity and transformed into new form during the Romanesque. In the article are synthetically presented the results of the research work of the writer about construction techniques of the most important churches in the city (S. Ambrogio, S. Simpliciano, S. Giovanni alle Fonti, S. Nazaro Maggiore, ..., trying to highlight the main changes between Late Antiquity and Romanesque. A large amount of stone material were used in Roman architecture of Milan and Lombardy, thanks to the geological variety of the territory. The Alps supplied granites, diorites, gneisses and marbles; the Prealps supplied limestones, dolomites, sandstones (Mesozoic and conglomerates (Quaternary; the Padània alluvial plain supplied pebbles, gravels, sands and clays (Quaternary. Each stone had a local use reaching the nearest towns (Como, Pavia, Milan, Bergamo, Brescia through waterways; the towns of the plain (Piacenza, Cremona, Mantua employed bricks made of local clay. Milano, the capital, employed also stones coming from abroad (limestones from Venetia and Friuli. White marbles of Apuanian Alps and coloured marbles of Eastern mediterranean were also diffused in Milan and other Lombard sites despite the laborious supplying. The stones quarried by the Romans were continuously used in the following centuries.

  13. Wabbes and the Milan Triennales: Representing the Belgian Nation

    NARCIS (Netherlands)

    Floré, F.M.W.; Ferran-Wabbes, Marie; Strauven, Iwan

    2012-01-01

    The work of the Brussels based furniture designer and interior architect Jules Wabbes played a significant role in the Belgian section of two successive Milan Triennials, that of 1957 and 1960. His sophisticated modern furniture and lightning designs were well qualified to represent the nation.

  14. Radiation protection courses in the Milan Copic Nuclear Training Centre

    International Nuclear Information System (INIS)

    Kozelj, M.; Stritar, A.

    1998-01-01

    We have briefly described the legal framework for the radiation protection training in Slovenia. The history of that activity at the Milan Copic Nuclear Training Center in Ljubljana is than described with the detailed description and summary of all performed courses.(author)

  15. Milan systemic family therapy: a review of 10 empirical investigations

    OpenAIRE

    Carr, Alan

    1991-01-01

    Ten empirical investigations of Milan Family Therapy (MFT) are reviewed in this paper. The studies include both single and comparative group outcome trials; investigations of therapeutic process; clinical audit and consumer satisfaction surveys. Substantive findings and methodological issues are discussed in the light of family therapy and individual psychotherapy research generally. Findings indicate that MFT may lead to symptomatic change in two-thirds to three-quarters of cases and to syst...

  16. The radioactive cloud on Milan and other neighbouring sites

    International Nuclear Information System (INIS)

    Capra, D.; Facchini, U.; Gianelle, V.; Marcazzan, G.M.; Ravasini, G.; Carreri, V.; Gualdi, R.; Sgorbati, G.; Tebaldi, G.

    1986-01-01

    The radioelements spread from the nuclear disaster in Ukraina reached the Milan atmosphere the evening of April, 30. A number of measurements started on air particulate; a number of radioelements was evidenced: Iodine, Tellerium, Cesium, Ruthenium and other. Then the presence of radioelements have been found in rain, in the first days of May, and consequently in the soil. Different samples show that the level of radioactivity in the Como lake area was greater than the average levels in Lombardy by a factor 2 or 3. Direct measurements of the gamma level on the ground give more evidence to this fact. The role of the rainfalls is discussed

  17. Transcultural itineraries of architect Milan Zloković

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    Blagojević Ljiljana

    2011-01-01

    Full Text Available The paper looks in more detail into the biography of one of the most prominent modern architects in Serbia, Milan Zloković (1898, Trieste - 1965, Belgrade, by focusing on the multicultural contexts of his childhood, youth and education as possible sources of his particular creative disposition and habit of mind. The argument is centred on exploring the course of the architect's interests, impressions, and studies, as they changed over the years in the complex historical conditions of the opening decades of the twentieth century. The paper argues that experiences from this period formed what is termed as the identity of multiple geographies, which guided much of Zloković's predilection in his later architectural work, and provided a transcultural frame of reference and breadth to his research. Traced back and analyzed against the biographical facts and events, are excerpts from his later articles and scholarly papers, most notably the ones where he provides references to architectural history of, inter alia, Byzantine architecture in Macedonia, medieval Serbian architecture, Italian Baroque, or traditional architecture of Boka Kotorska. The aim of the research is to contribute to a broader understanding of the complex cultural basis and polyvalent discourse of Serbian modernism, in the foundation of which Milan Zloković had a decisive role.

  18. Early Greek Typography in Milan: A Historical Note on a New Greek Typeface.

    Science.gov (United States)

    Wallraff, Martin

    1997-01-01

    Discusses the history of Greek typography, focusing on the first book to be entirely printed in Greek in 1476 and the series of new typefaces that resulted. Cites Milan as a center of Greek printing in the early history of Greek typography. Describes a revival of one of these typefaces created under the name of Milan Greek. (PA)

  19. The Milan Project: a newborn hearing screening programme.

    Science.gov (United States)

    Pastorino, Giancarlo; Sergi, Paola; Mastrangelo, Massimo; Ravazzani, Paolo; Tognola, Gabriella; Parazzini, Marta; Mosca, Fabio; Pugni, Lorenza; Grandori, Ferdinando

    2005-04-01

    Since 1997 a newborn hearing screening programme has been implemented by the U.O. Neurologia-Neurofisiopatologia and Dipartimento di Neonatologia of the Istituti Clinici di Perfezionamento ICP in Milan for both babies with no risk and those at risk of hearing impairment. This programme was named the Milan Project. The protocol for no-risk babies consisted of three stages: in the first two stages, newborns were tested with transient click-evoked otoacoustic emissions (TEOAE), in the third one with conventional auditory brainstem responses (ABR). The first TEOAE test was performed by 36 h of age, before discharge, the second one after 15-30 d in case of referral, and the third one, by ABR, for those babies who failed the second TEOAE stage. Newborns at audiological risk were submitted to conventional ABR before the third month of corrected age. Some of this latter population was also submitted to the TEOAE test. The entire tested population (no-risk babies and newborns at audiological risk) consisted of 19 777 babies: 19 290 without risk ("no risk") and 487 at risk ("at risk"). During the course of the Milan Project, hearing impairment (ABR threshold equal to or greater than 40 dB nHL) was identified in 63 newborns (19 from the no-risk and 44 from the at-risk population), with a prevalence of 0.32%. Bilateral hearing impairment (BHI) was found in 33 newborns (10 from the no-risk and 23 from the at-risk population), corresponding to 0.17%. Among infants with bilateral hearing impairment, 30.3% had no risk factors. The prevalence of hearing impairment was determined on days 15-30 after birth. The results show that the implementation of a hospital-based, universal neonatal hearing screening programme for babies with and without audiological risk is feasible and effective. The effectiveness of the programme has increased as a function of the years since its inception, with a strong decrease in the referral rate. Further improvement is obtained if the TEOAE measurements

  20. Archaeometric study of fictile tubes from three churches in Milan

    Science.gov (United States)

    Galli, A.; Bonizzoni, L.; Martini, M.; Sibilia, E.

    2008-07-01

    Fictile tubes (or vaulting tubes) are architectural elements that sustain and underline the shapes of cupolas and vaults. Several of these, sampled in three churches of Milan (S. Ambrogio, S. Lorenzo and Duomo) have been recently dated at the Archaeometry Laboratory of Milano Bicocca University. These architectural elements, differently shaped, styled and sampled from different structures, were all produced, according to thermoluminescence (TL), in the period 970 1080 AD. Energy dispersive X-rays fluorescence (EDXRF) measurements were performed to obtain the elemental composition of the clays and to attempt a classification of the samples. Multivariate PCA (principal components analysis) analyses and HCA (hierarchical clusters analysis) did not show any grouping of similarity. On the basis of the results, a tentative historical interpretation could be proposed.

  1. ESO Council Visits First VLT Unit Telescope Structure in Milan

    Science.gov (United States)

    1995-12-01

    As the ESO Very Large Telescope (VLT) rapidly takes on shape, Europe has just come one step closer to the realisation of its 556 million DEM astronomical showcase project. Last week, the ESO Council held its semi-annual meeting in Milan (Italy) [1]. During a break in the long agenda list, Council members had the opportunity to visit the Ansaldo factory in the outskirts of this city and to see for the first time the assembled mechanical structure of one of the four 8.2-metre VLT Unit telescopes. This Press Release is accompanied by a photo that shows the ESO Council delegates in front of the giant telescope. After a long climb up the steep staircase to the large Nasmyth platform at the side of the telescope where the astronomical instruments will later be placed, Dr. Peter Creola (Switzerland) , President of the ESO Council and a mechanics expert, grabbed the handrail and surveyed the structure with a professional eye: `I knew it was going to be big, but not that enormous!', he said. Other delegates experienced similar feelings, especially when they watched the 430 tonnes of steel in the 24-metre tall and squat structure turn smoothly and silently around the vertical axis. The Chairman of the ESO Scientific Technical Committee (STC), Dr. Johannes Andersen (Denmark) , summarized his first, close encounter with the VLT by `This is great fun!' and several of his colleague astronomers were soon seen in various corners of the vast structure, engaged in elated discussions about the first scientific investigations to be done with the VLT in two years' time. The VLT Main Structures The visit by Council took place at the invitation of Ansaldo Energia S.p.A. (Genova), EIE-European Industrial Engineering S.r.I. (Venice) and SOIMI-Societa Impianti Industriale S.p.A. (Milan), the three Italian enterprises responsible for the construction of the main structures of the VLT 8.2-metre Unit telescopes. Short speeches were given on this occasion by Drs. Ferruccio Bressani (Ansaldo

  2. The Soundscape Quality in Some Urban Parks in Milan, Italy

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    Giovanni Zambon

    2013-06-01

    Full Text Available Urban parks play an important role in preserving and promoting the health of citizens who are often exposed to noise pollution and the stress of daily life. The present study describes the main results obtained from a survey performed in five urban parks in Milan. Measurements of the acoustic environment were carried out in 29 sites together with interviews with 231 users on certain aspects of the parks not limited to merely sound. Acoustic data show that the surveyed parks mostly do not comply with the noise limit issued by the Italian legislation on protected areas. The unweighted 1/3-octave spectrum centre of gravity G and LA50 perform satisfactorily in discriminating among the acoustic environments. Such clear distinction was not observed in the subjective ratings on the perceived quality of the soundscape, likely due to the influence by non-acoustic factors that act as mediators in the assessment. This hypothesis is supported by the collected data on the perceived quality of quietness, which was rated worse than that of the soundscape. Comparing acoustic data with ratings, the perceived quality of the total environment was found to be less dependent on LAeq than soundscape and quietness.

  3. The valorisation of abandoned railway yards. The case of Milan

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    Elena Mussinelli

    2012-04-01

    Full Text Available Milan’s urban growth was heavily influenced by the structure of the rail network for transporting goods and people. The great railway yards that used to service the industrial system have now lost their raison d'être after the relocation of industrial plants and the tertiary sector dynamics took over the city. These have become large abandoned brownfields or soon to be abandoned, totaling over 1,300,000 square meters, located mainly along the urban belt surrounding the city walls, often in densely built environments. Since 2005 these areas were the subject of several agreements between the City of Milan, State Railways SpA (FS and the Lombardy Region, to examine various scenarios and the feasibility of their conversion, as confirmed in the draft of the new Territorial Government Plan (PGT, which identifies the Areas of Urban Transformation. Scenarios and assumptions that, in the current revision of the PGT, must approach the strategic role of this rich heritage from an environmental regeneration and valorization perspective extended to urban and metropolitan scales.

  4. The soundscape quality in some urban parks in Milan, Italy.

    Science.gov (United States)

    Brambilla, Giovanni; Gallo, Veronica; Zambon, Giovanni

    2013-06-06

    Urban parks play an important role in preserving and promoting the health of citizens who are often exposed to noise pollution and the stress of daily life. The present study describes the main results obtained from a survey performed in five urban parks in Milan. Measurements of the acoustic environment were carried out in 29 sites together with interviews with 231 users on certain aspects of the parks not limited to merely sound. Acoustic data show that the surveyed parks mostly do not comply with the noise limit issued by the Italian legislation on protected areas. The unweighted 1/3-octave spectrum centre of gravity G and LA50 perform satisfactorily in discriminating among the acoustic environments. Such clear distinction was not observed in the subjective ratings on the perceived quality of the soundscape, likely due to the influence by non-acoustic factors that act as mediators in the assessment. This hypothesis is supported by the collected data on the perceived quality of quietness, which was rated worse than that of the soundscape. Comparing acoustic data with ratings, the perceived quality of the total environment was found to be less dependent on LAeq than soundscape and quietness.

  5. The return of the dinar: Metal coins of Prince and King Milan Obrenovic (1854-1901

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    Pantelić Svetlana

    2014-01-01

    Full Text Available In Serbia liberated from the Turkish rule, the copper coins of Mihailo M. Obrenovic were 'the first Serbian coins minted after the medieval coins', which were, however, 'put into circulation after Mihailo's unfortunate demise', at the beginning of Prince Milan's reign. The coins of Prince Milan are specific because they were the first coins to bear the inscription dinar, named after the medieval coins used in the Serbian states. The silver 1- and 2-dinar and 50-para coins were minted in 1875 in the first years of the adult Prince Milan Obrenovic's reign, whereas the silver 50-para, 1-, 2- and 5-dinar coins, the copper 5- and 10-para coins, and the gold 20-dinar coins, were minted in 1879, as the crown to the final independence of the Princedom of Serbia from the Turkish rule.

  6. Turistički značaj galerije 'Milan Konjović' u Somboru

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    Besermenji Snežana

    2008-01-01

    Full Text Available A gallery 'Milan Konjović' in Sombor is a culture establishment in which there are exhibited works of a famous impressionist Milan Konjovic. It was opened in 1966 and it is placed in a Galley house, on the Square of Holy Three. Works of Milan Konjović are presented by chronological productions and occasional thematic exhibitions, and a collection consists of 1060 works today. In order to notice the tourist importance of this establishment, in this work there will be done a SWOT analysis which will point to internal abilities and internal weakness on one hand and, on the other hand, there will be analyzed exterior possibilities and those are chances and threats from the surroundings. Considering the fact that conditions in our institutions of culture are on unsatisfactory level, in this paper two affirmed galleries in London will be presented: the Tate Gallery and the Tate Modern, which represent positive example of successful management in cultural institutions.

  7. Integrating decision support tools and environmental information systems: a case study on the Province of Milan

    International Nuclear Information System (INIS)

    Bagli, S.; Pistocchi, A.; Mazzoli, P.; Valentini, P.

    2006-01-01

    The paper demonstrates an application of advanced decision support tools within the framework of the environmental information system of the Province of Milan. These tools include environmental simulation models, multi criteria analysis, risk analysis and environmental accounting for marketable emission permits. After describing the general structure of the system, three demonstrational case studies are introduced concerning: groundwater pollution management; atmospheric pollution management; urban environmental quality perception and management. In the conclusion, potential use of tools like the ones implemented by the province of Milan within the framework of Local Agenda 21 processes is recalled [it

  8. Literary Narratives as Constituents of Political Worlds: The Case of Milan Kundera

    Czech Academy of Sciences Publication Activity Database

    Fořt, Bohumil

    2012/2014, 7/8 (2014), s. 38-50 ISSN 2213-0535 Institutional support: RVO:68378068 Keywords : fictional world * politics * Kundera, Milan Subject RIV: AJ - Letters, Mass-media, Audiovision http://cf.hum.uva.nl/narratology/issue/7/a12_Bohumil_Fort.html

  9. Construction and assembling of the trim coils for the Milan superconducting cyclotron

    International Nuclear Information System (INIS)

    Baccaglioni, G.; Cartegni, G.C.; Fusetti, M.; Gini, L.; Grilli, L.

    1986-01-01

    This paper presents the main characteristics of the trim coils realized for the heavy ions superconducting cyclotron under construction at the Milan University. The guidelines in the choice of the conductor size, of the insulation and cooling parameters are discussed in some details. The main operations in the coils construction, as winding, impregnation, electrical tests and assembling, are described

  10. Ärimees ootab annetuse eest Keskerakonnalt vastuteenet / Dannar Leitmaa, Erik Rand, Milan Bališ

    Index Scriptorium Estoniae

    Leitmaa, Dannar, 1982-

    2009-01-01

    Slovakkia ärimehed annetasid Eesti Keskerakonnale 1,4 mln. krooni, avaliku teenistuse eetikakoodeksi autor Ivar Tallo peab välismaistelt annetajatelt raha saamist taunitavaks. Annetustest teistele erakondadele I kvartalis. Vt. samas lühiintervjuud Milan Bališiga

  11. SUSTAINABILITY OF SHORT FOOD SUPPLY CHAINS: ANALYSIS OF RAW MATERIAL SUPPLY IN MILAN PUBLIC SCHOOL CATERING

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    G. D’Anna

    2009-09-01

    Full Text Available The demand of short food supply chains is becoming more pressing by consumers, especially in the largest school catering. The implementation of the short chain in a large catering company of Milan, is described in this practical contribution. Several aspects of short food chains sustainability: legal, commercial and economic sustainability, hygienic and gastronomic sustainability, are discussed.

  12. Follow-up of 53 Alzheimer patients with the MODA (Milan Overall Dementia Assessment).

    Science.gov (United States)

    Capitani, E; Manzoni, L; Spinnler, H

    1997-01-01

    Fifty-three patients affected by Alzheimer's disease entered a longitudinal survey aimed at studying which factors influence the rate of progression, assessed by means of the Milan Overall Dementia Assessment (MODA). The second examination was carried out, on average, after 16 months from the first assessment. Only age proved to influence the decline rate, which was faster in elders.

  13. Mass gatherings in Italy: a study from the 2015 Milan Expo

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    Pietro Marino

    2016-07-01

    Full Text Available Introduction. A mass gathering (MG is when a large number of people come together in a particular location for a specific purpose. Expo 2015 was an universal exposition hosted by Milan, Italy. The Pre-Hospital Emergency Company (AREU of Lombardy Region (Milan-Italy was involved in planning and managing the emergency rescue response inside the Expo 2015 area in Milan. In this paper, we review the AREU medical and public health response for the 2015 Milan Expo. Methods. Existing risk-assessment processes for MGs were used (the Arbon Predictive Score and Maurer Score to define the expected resources and the impact on the health systems. The objective of the plan was to reduce the impact of the event by adopting the model of First Aid Points (advanced medical posts deployed in the event site acting as ‘first health filters’ for the hospital network in Milan. Results. Our data indicate that 13,579 visitors were rescued in the ‘Red Area’ from 1 May to 31 October (with an average of 73 cases per day; 9,501 of them needed initial treatment or observation time at the First Aid Points, 1,289 of them were hospitalised (1% Red code, 29% Yellow code, 70% Green code; 65% of patients (57% female, with a mean age of 37 years old had medical problems. Fatigue, light- headedness, dizziness, syncope, loss of consciousness and headache were the prevalent medical diagnoses. Conclusions. Our study confirms that environmental factors, such as the weather, can contribute to large numbers of ill people at MGs. Overall, the AREU of Lombardy Region demonstrated excellent preparation for the Expo 2015 MG. Flexibility, integration and strong cooperation between the pre-hospital settings and hospitals were incorporated into the application of the plan. The final data showed the effectiveness of the adopted model and the reduced impact on the hospital network.

  14. Religious tolerance in the Edict of Milan and in the Constitution of Medina

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    Đurić Drago

    2013-01-01

    Full Text Available In this paper, we will try to offer a blueprint for a more general discussion of the relation of how the question of religious tolerance appears in two documents that the Christian and Islamic traditions recognize and celebrate: namely, the Edict of Milan and the Constitution of Medina. These documents were revolutionary for their time. However, these documents alone, as well as religious teachings, on which they are based, cannot be the measure of relations in our time. They are presented in the conceptual framework and value system that prevailed at the time when these teachings and documents were created. Many relations the documents refer to no longer exist. For example, while the Edict of Milan affirms the general right to religion, and the Constitution of Medina affirms the mutual tolerance for Abrahamic, monotheistic religions - people who now declare themselves as atheists or agnostics are not even mentioned.

  15. Satellite air temperature estimation for monitoring the canopy layer heat island of Milan

    DEFF Research Database (Denmark)

    Pichierri, Manuele; Bonafoni, Stefania; Biondi, Riccardo

    2012-01-01

    across the city center from June to September confirming that, in Milan, urban heating is not an occasional phenomenon. Furthermore, this study shows the utility of space missions to monitor the metropolis heat islands if they are able to provide nighttime observations when CLHI peaks are generally......In this work, satellite maps of the urban heat island of Milan are produced using satellite-based infrared sensor data. For this aim, we developed suitable algorithms employing satellite brightness temperatures for the direct air temperature estimation 2 m above the surface (canopy layer), showing...... 2007 and 2010 were processed. Analysis of the canopy layer heat island (CLHI) maps during summer months reveals an average heat island effect of 3–4K during nighttime (with some peaks around 5K) and a weak CLHI intensity during daytime. In addition, the satellite maps reveal a well defined island shape...

  16. Altered Rhythms. Urban façades in post-war Milan

    Directory of Open Access Journals (Sweden)

    Magda Mària Serrano

    2017-10-01

    Full Text Available Urban façades are the outward manifestation of the character of a city, and are composed of elements that respond to rhythmic sequences in consonance with the internal order of the rooms behind them. In post-war Milan, façades were used as a field of experimentation by a group of architects, some of whom were also artists and designers, who saw themselves and can be seen as ambassadors for the future modernity of a city devastated by war. This article explains how the urban façades of Milan, based as they were on the themes drawn from the Italian compositional tradition, offer a wide variety of elements, figures and rhythms, altering and transgressing the compositional canons through the use of mechanisms that in some cases are closer to painting or sculpture than to architecture.

  17. Service Areas, Motorway Exits, Railway Stations: New Entrances to Access Expo 2015 Landscapes, between Milan & Turin

    Directory of Open Access Journals (Sweden)

    Andrea Rolando

    2014-12-01

    Full Text Available This paper aims at understanding how a better relationship between infrastructures and landscapes can be established, by encouraging new ways to experience and effectively use the places that are located near the infrastructural nodes. The work starts from the identification of a specific case study: the landscape in-between the cities of Milan and Turin, that are connected by the infrastructural bundle made of the three lines of the regional / historical railways, the motorway and the new tracks of the high speed train. The research highlights cultural heritage sites and places of interest, points out a series of areas and routes that connect them with the infrastructure. The Milan 2015 Expo could in this sense be a very powerful catalyst, by encouraging these intermodal uses of the infrastructural bundle to reach and truly experience the agricultural and cultural landscapes located around it.

  18. Milan rainfall series: Reconstruction of monthly precipitation data; Osservazioni pluviometriche a Milano: ricostruzione delle precipitazioni mensili

    Energy Technology Data Exchange (ETDEWEB)

    Maugeri, M. [Milan Univ. (Italy). Ist. di Fisica Generale Applicata; Buffoni, L.; Chlistovsky, F. [Osservatorio Astronomico, Brera (Italy)

    1995-05-01

    A detailed historical study on the methodologies about rain acquisition in Milan-Brera during the least 230 years is presented. The reliability of several periods of the series is described on the basis of the used methodologies and of the disponibility of original manuscripts. The monthly, yearly and seasonal corrected values of the rainfalls for the period 1764-1993 are published. Some data analysis is then presented in order both to describe the trend of yearly rainfalls and to show how the inclusion of the first period data (probably more affected by errors) modifies the principal features of Milan rainfalls. Finally a new set of normal monthly, seasonal and yearly rainfalls data is presented.

  19. Evolution of Milan microclimate in XX century. Evoluzione del microclima milanese nel corso del secolo XX

    Energy Technology Data Exchange (ETDEWEB)

    Schieroni, A. (Lombardia Risorse SpA, Milan (Italy))

    Within the framework of studies to correlate the use of fossil fuels with urban area thermal pollution, this article examines the local microclimate of Milan, describing the main features of the so-called 'heat island' phenomenon and analyzing the evolution of ambient temperatures. Two different kinds of data on urban temperatures were employed: the hourly measurements taken by the Multinational Presidium for Hygiene and Prevention, run by the Local Sanitary Unit No. 75 of Milan, in the period ranging from 1985 to 1990, and the maximum and minimum daily values referring to the period between 1909 and 1991 (data supplied by the Meteorologic Observatory of Brera-Duomo). The standard year, worked out in the framework of the C. N. R. (National Research Centre) Finalized Energy Project and referring to the meteorological station of Linate Airport, was employed in order to highlight the difference between the thermal behaviour of the urban and the extra-urban area.

  20. Treatment Algorithm for the Hypertension Specialist after the Milan Meeting in 2007

    Czech Academy of Sciences Publication Activity Database

    Peleška, Jan; Anger, Z.; Buchtela, David; Tomečková, Marie; Veselý, Arnošt; Zvárová, Jana

    2007-01-01

    Roč. 30 (2007), s. 374-374 ISSN 1420-4096. [Central European Meeting on Hypertension and Cardiovascular Disease Prevention. 11.10.2007-13.10.2007, Kraków] R&D Projects: GA AV ČR 1ET200300413 Institutional research plan: CEZ:AV0Z10300504 Keywords : hypertension specialist * treatment algorithm for the hypertension * treatment after the Milan Meeting in 2007 Subject RIV: FA - Cardiovascular Disease s incl. Cardiotharic Surgery

  1. Territorial embeddedness and virtual connections of knowledge and creative workers in Milan

    Directory of Open Access Journals (Sweden)

    Marianna d’Ovidio

    2014-04-01

    Full Text Available The paper discusses the relation between territorial embeddedness and virtual connections among knowledge and creative workers in Milan by challenging the idea that co-presence is crucial for interaction and that face-to-face (F2F relations are essential for their success. Knowledge and creative workers are thus embedded in a wider "space", that is not necessarily a physical one, but also virtual and ICT mediated.

  2. Total suspended particulates in Milan, Italy. Studi sul particolato nell'atmosfera milanese

    Energy Technology Data Exchange (ETDEWEB)

    Valentini, M.; Verderio, C.; Maugeri, M. (Milan Univ. (Italy). Ist. di Fisica Generale Applicata); Novo, A. (Ente Nazionale per l' Energia Elettrica, Milan (Italy). Centro Termica e Nucleare)

    1993-05-01

    The paper describes a group of measurements taken of the suspended particulate in the Milan atmosphere. The samples were collected on membrane filters and then analyzed using fluorescence methods. Many elements were found and quantitatively determined, from sulphur to lead. The collection of particulate, at a height of 25 meters above ground level, was made over a period of three years at the Brera Tower Air Quality Station.

  3. Ongoing large measles outbreak with nosocomial transmission in Milan, northern Italy, March-August 2017.

    Science.gov (United States)

    Amendola, Antonella; Bianchi, Silvia; Frati, Elena R; Ciceri, Giulia; Faccini, Marino; Senatore, Sabrina; Colzani, Daniela; Lamberti, Anna; Baggieri, Melissa; Cereda, Danilo; Gramegna, Maria; Nicoletti, Loredana; Magurano, Fabio; Tanzi, Elisabetta

    2017-08-17

    A large measles outbreak has been ongoing in Milan and surrounding areas. From 1 March to 30 June 2017, 203 measles cases were laboratory-confirmed (108 sporadic cases and 95 related to 47 clusters). Phylogenetic analysis revealed the co-circulation of two different genotypes, D8 and B3. Both genotypes caused nosocomial clusters in two hospitals. The rapid analysis of epidemiological and phylogenetic data allowed effective surveillance and tracking of transmission pathways. This article is copyright of The Authors, 2017.

  4. Active and passive monitoring of benzene in Milan from 1992 up to today

    International Nuclear Information System (INIS)

    Lerda, D.; Robles, P.; Astori, M.; Barletta, M.; Canzi, R.; Barilli, L.

    1999-01-01

    The air quality degradation in large urban areas, mainly due to the traffic, is evaluated through the measurement of pollutants coming, directly or indirectly, from the traffic itself. Due to its cancerogenicity, a quality standard for benzene has been settled by D.M.25/11/1994, which obliges this measure in towns having more than 150.000 inhabitants.Starting from 1992, Milan P.M.I.P. has been controlling benzene and other homologues concentrations in air with routine and campaign measurements. Concentrations change depends both on variations of fuel formulation and on the renewal of the cars fleet. As a matter of fact, the lower benzene percentage in fuels and the use of tailpipes with catalytic converter greatly reduced the emission of these compounds in air, giving an estimate annual average lower than the impose limit. In an urban area, an estimate of an average concentration starting from the three sampling points according to the low can give a value far from the real average level; to solve this problem Milan P.M.I.P. programmed an annual campaign with daily sampling in 24 sites homogeneously located in Milan territory [it

  5. Cradles of industry and occupational medicine in the modern world: Milan 1906 -- Annus Mirabilis.

    Science.gov (United States)

    Baldasseroni, A; Carnevale, F; Tomassini, L

    2013-01-01

    The example examined is Milan, Italy's main industrial city, where the great International Exhibition was held in 1906. This was the culmination of a period of accelerated industrial growth that modern-day historiography considers to be when Italy's first real industrial revolution began. The twenty-five years between the National Industrial Exhibition of 1881, which was also held in Milan, and the 1906 Exhibition truly reflected a period which was crucial for this transformation to take of. Alongside industry, which was then going through a phase of reorganization and development, Milanese civil society was increasingly turning its interest and attention to what was called the "social question". In an atmosphere of debate and exchange of ideas and experience with Turin, another major industrial city of the north and the birthplace of the Italian engineering and automobile industries, social organizations, political parties and trade unions began to be established thus heralding the Italian approach towards twentieth-century welfare. This is the context in which the first International Congress on Occupational Diseases was held in Milan from 9 to 14 June 1906 within the framework of the International Exhibition. The success achieved with this initiative. organized by Luigi Devoto and Malachia De Cristoforis, which was to continue with the founding of the International Permanent Commission on Occupational Health, showed that the time was ripe for a new subject to appear on the scene--the occupational health physician--who from then on was to play an important role in the promotion of workers' health. The article outlines the main features of the Italian industrial transformation at the turn of the new century with special attention focused on Milan, the capital of industry in Italy. It also describes the impact on public opinion caused by the events surrounding the epic construction of the transalpine railway tunnels which began in 1856 with the Mont Cenis tunnel

  6. Sur les traces de Franz Kafka dans l’œuvre de Milan Kundera // In the footsteps of Franz Kafka in the work of Milan Kundera

    Directory of Open Access Journals (Sweden)

    Lenka Žehrová

    2015-12-01

    Full Text Available Franz Kafka is undoubtebly an important part of the literary canon of the Central Europe and especially of the canon formed by Milan Kundera in his works. Kundera considers Kafka to be one of his principal masters. He sees Kafka as an antecendent of surrealism and existencialism. According to his collection of essays The Art of the Novel, Kafka is the prototype of the ideal author who invites us to cross the border of the probable showing us the world from the other side. Thus, we can observe the human existence in different and better way. By showing this, he fills up the main task of every novelist. The contribution will analyze the alludes of Kafka in the work of Kundera and will try to describe their character and explain how Kundera works with examples of Kafka and his work in his own books.

  7. The Milan Project: A New Method for High-Assurance and High-Performance Computing on Large-Scale Distributed Platforms

    National Research Council Canada - National Science Library

    Kedem, Zvi

    2000-01-01

    The MILAN project, a joint effort involving Arizona State University and New York University, has produced and validated fundamental techniques for the realization of efficient, reliable, predictable...

  8. Living like a king? The entourage of Odet de Foix, vicomte de Lautrec, governor of Milan.

    Directory of Open Access Journals (Sweden)

    Philippa Woodcock

    2015-11-01

    Full Text Available In the early sixteenth century, the de Foix family were both kin and intimate councillors to the Valois kings, Louis XII and François I. With a powerbase in Guyenne, the de Foix tried to use their connections at court to profit from the French conquest of Milan, 1499-1522. This paper will explore the career of one prominent family member, Odet de Foix, vicomte de Lautrec (1483-1528. Lautrec was a Marshal of France, who served in Italy as a soldier and governor. He was key to the royal entourage, amongst François I’s intimates at the Field of the Cloth of Gold. His sister, Françoise, was also the king’s mistress. The paper will examine Lautrec’s entourage from two aspects. Firstly, it asks how Lautrec established his entourage from his experience in Navarre and Italy and as a member of the royal retinue. It establishes the importance of familial and regional ties, but also demonstrates the important role played by men of talent. Secondly, it explores Lautrec's relationship to his entourage once governor of Milan. Were ties of blood, career or positions of Italian prestige the most important for a governor when he chose his intimates? Were compromises made with Italian traditions and elites to sustain his rule? Did he learn from the experience and failures of previous governors?  The article contributes to a gap in scholarship for the later period of French Milan from 1515-1522. It also adds to our knowledge of the behaviour and ambitions of early modern governors.

  9. The Milan System for Reporting Salivary Gland Cytopathology: Analysis and suggestions of initial survey.

    Science.gov (United States)

    Rossi, Esther Diana; Faquin, William C; Baloch, Zubair; Barkan, Güliz A; Foschini, Maria Pia; Pusztaszeri, Marc; Vielh, Philippe; Kurtycz, Daniel F I

    2017-10-01

    An international panel of experts in the field of salivary gland cytology (SGC), supported by the American Society of Cytopathology (ASC) and the International Academy of Cytology, conducted a survey to seek evidence and practice patterns regarding SGC. Results were used to provide focus for the proposed Milan System for Reporting Salivary Gland Cytopathology. The study group, formed during the 2015 European Congress of Cytology held in Milan, Italy, generated a survey that included 49 specific questions related to the taxonomies, practices, and diagnostic entities of salivary cytology. Qualtrics software was used as the study platform. Software and server support were provided by the division of information technology at the University of Wisconsin. The survey was available online from November 2015 until February 2016. Participants were invited through the Web sites of the ASC, the International Academy of Cytology, and the Papanicolaou Society of Cytopathology as well as by the ASC e-mail "ListServe"; responses were evaluated by the Milan System editors. Responses from a total of 515 participants were collected and reviewed. A total of 347 participants provided demographic data information. Responses revealed variations in diagnostic practice and subsequent management. Participants believed that the acceptable rate for nondiagnostic samples should not be higher than 10%. There were varied opinions regarding the approach to neoplastic lesions of uncertain malignant potential, those that may or may have not local invasion and distant spread. Results of the survey demonstrated strong support for the development of a unified system for reporting SGC. Cancer Cytopathol 2017;125:757-66. © 2017 American Cancer Society. © 2017 American Cancer Society.

  10. [Assessment of pesticide residues in food of plant origin in Milan (Italy), 2008-2011].

    Science.gov (United States)

    Tesauro, Marina; Cesaria, Maria Concetta; Fracchia, Simonetta; Benzoni, Massimo; Bollani, Massimiliano; Consonni, Michela; Bianchi, Annalisa

    2013-01-01

    To monitor the presence of pesticide residues in food of plant origin in Milan from 1 July 2008 to 31 December 2011. Food of plant origin found in fruit and vegetable markets and in supermarkets was analysed, to evaluate whether it was contaminated by any seventy active principles of pesticides. Two hundred seventy-seven samples of fruits and vegetables were analysed. No pesticide residues were found in 61.7% of the samples, 37.9% had residues below the maximum threshold and 0.4% had residues above the threshold. Results are satisfactory and in agreement with national and international data.

  11. West Nile Virus (WNV seroprevalence in a blood donors group of Milan

    Directory of Open Access Journals (Sweden)

    Giovanna Lunghi

    2012-09-01

    Full Text Available A seroprevalence study for anti West Nile virus was carried out among 864 healthy blood donors living in the metropolitan area of Milan by using a commercially available ELISA method. In addition, the performance of a novel ELISA assay for WNV antibodies was assessed. The sero-prevalence rate of WNV antibodies was 0.57% thus showing that WNV is likely circulating also in this up to now unknown area. The overall sensitivity and specificity of the novel ELISA were 99.9% and 45.4%, respectively, well comparable with that of the chosen reference immunoenzimatic method.

  12. Evolution of traffic emissions in European urban areas: Milan case study

    International Nuclear Information System (INIS)

    Giugliano, M.; Cemin, A.; Cernuschi, S.

    1992-01-01

    The worldwide increasing role of mobile sources on the air quality of urban areas requires a careful evaluation of all the potential intervention policies for the reduction of traffic related emissions. The accurate description of the evolution of the source, following the renewal of the fleet with vehicles regulated by stricter emission standards, represents the basic premise for this evaluation. This paper outlines a proposed methodology for the evaluation of the trend of mobile source emissions, implemented on the calculation program EMISMOB, and reports the results obtained with its application to predict the evolution of traffic emissions in the urban area of Milan (Italy) until the year 2010

  13. Italy on the spotlight: Expo Milan 2015 and Italian Journal of Food Science

    Directory of Open Access Journals (Sweden)

    P. Fantozzi

    2015-12-01

    Full Text Available The year 2015 will certainly be remembered as the Year of the Universal Exposition (EXPO hosted in Milan, Italy, focusing on a hot theme in the current scenario: “Feeding the Planet, Energyfor Life”.This event has drawn a wide international attention towards Italy as a country with peculiar and valuable food traditions, thus strengthening its reputation as “gastronomic capital of theworld” rich in protected designation of origin products (PDOs and characterised by a longstanding food culture.

  14. Preliminary Statistics from the NASA Alphasat Beacon Receiver in Milan, Italy

    Science.gov (United States)

    Nessel, James; Zemba, Michael; Morse, Jacquelynne; Luini, Lorenzo; Riva, Carlo

    2015-01-01

    NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 gigahertz band. NASA GRC has developed and installed a K/Q-band (20/40 gigahertz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20/40 gigahertz signals broadcast from the Alphasat Aldo Paraboni TDP no. 5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we provide an overview of the design and data calibration procedure, and present 6 months of preliminary statistics of the NASA propagation terminal, which has been installed and operating in Milan since May 2014. The Q-band receiver has demonstrated a dynamic range of 40 decibels at an 8-hertz sampling rate. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models.

  15. Integrating Laser Scanner and Bim for Conservation and Reuse: "the Lyric Theatre of Milan"

    Science.gov (United States)

    Utica, G.; Pinti, L.; Guzzoni, L.; Bonelli, S.; Brizzolari, A.

    2017-12-01

    The paper underlines the importance to apply a methodology that integrates the Building Information Modeling (BIM), Work Breakdown Structure (WBS) and the Laser Scanner tool in conservation and reuse projects. As it is known, the laser scanner technology provides a survey of the building object which is more accurate rather than that carried out using traditional methodologies. Today most existing buildings present their attributes in a dispersed way, stored and collected in paper documents, in sheets of equipment information, in file folders of maintenance records. In some cases, it is difficult to find updated technical documentation and the research of reliable data can be a cost and time-consuming process. Therefore, this new survey technology, embedded with BIM systems represents a valid tool to obtain a coherent picture of the building state. The following case consists in the conservation and reuse project of Milan Lyric Theatre, started in 2013 from the collaboration between the Milan Polytechnic and the Municipality. This project first attempts to integrate these new techniques which are already professional standards in many other countries such as the US, Norway, Finland, England and so on. Concerning the methodology, the choice has been to use BIM software for the structured analysis of the project, with the aim to define a single code of communication to develop a coherent documentation according to rules in a consistent manner and in tight schedules. This process provides the definition of an effective and efficient operating method that can be applied to other projects.

  16. Sound quality indicators for urban places in Paris cross-validated by Milan data.

    Science.gov (United States)

    Ricciardi, Paola; Delaitre, Pauline; Lavandier, Catherine; Torchia, Francesca; Aumond, Pierre

    2015-10-01

    A specific smartphone application was developed to collect perceptive and acoustic data in Paris. About 3400 questionnaires were analyzed, regarding the global sound environment characterization, the perceived loudness of some emergent sources and the presence time ratio of sources that do not emerge from the background. Sound pressure level was recorded each second from the mobile phone's microphone during a 10-min period. The aim of this study is to propose indicators of urban sound quality based on linear regressions with perceptive variables. A cross validation of the quality models extracted from Paris data was carried out by conducting the same survey in Milan. The proposed sound quality general model is correlated with the real perceived sound quality (72%). Another model without visual amenity and familiarity is 58% correlated with perceived sound quality. In order to improve the sound quality indicator, a site classification was performed by Kohonen's Artificial Neural Network algorithm, and seven specific class models were developed. These specific models attribute more importance on source events and are slightly closer to the individual data than the global model. In general, the Parisian models underestimate the sound quality of Milan environments assessed by Italian people.

  17. Binder characterisation of mortars used at different ages in the San Lorenzo church in Milan

    International Nuclear Information System (INIS)

    Bertolini, Luca; Carsana, Maddalena; Gastaldi, Matteo; Lollini, Federica; Redaelli, Elena

    2013-01-01

    The paper describes a study on the mortars of the basilica of San Lorenzo in Milan, which was carried out to support an archaeological study aimed at dating and documenting the construction techniques used throughout the centuries. The church, which was founded between the 4th and 5th century, at the end of the period when Milan was the capital of the Roman Empire, was subjected in time to extensions, collapses and reconstructions that lasted until the Renaissance period and even later on. Thanks to the good state of conservation, San Lorenzo church is a collection of materials and construction techniques throughout a period of more than a millennium. Mortars were investigated in order to compare the binders used for structural elements built in different historical ages. From an archaeological study, samples of mortars attributed to the late Roman period, the Middle Ages and the Renaissance were available. The binder of each sample was separated by the aggregates and it was characterised on the basis of X-ray diffraction analysis, thermogravimetric analysis and scanning electron microscopy. Constituents of the binder were identified and their origin is discussed in order to investigate if they could be attributed to the original composition of the binder or to possible alteration in time due to atmospheric pollution. Results show that, even though the binder is mainly based on magnesian lime, there are significant differences in the microstructure of the binding matrix used in mortars ascribed to the different historical periods. In the Roman period, in correspondence of the structural elements that required higher strength, also hydraulic cocciopesto mortars were detected. Gypsum was found in most samples, which was maybe added intentionally. - Highlights: • Binders of mortars of San Lorenzo church in Milan were investigated. • Roman, Middle Ages and Renaissance samples were studied by XRD, TG and SEM. • Magnesian-lime binders containing silico

  18. Binder characterisation of mortars used at different ages in the San Lorenzo church in Milan

    Energy Technology Data Exchange (ETDEWEB)

    Bertolini, Luca, E-mail: luca.bertolini@polimi.it; Carsana, Maddalena, E-mail: maddalena.carsana@polimi.it; Gastaldi, Matteo, E-mail: matteo.gastaldi@polimi.it; Lollini, Federica, E-mail: federica.lollini@polimi.it; Redaelli, Elena, E-mail: elena.redaelli@polimi.it

    2013-06-15

    The paper describes a study on the mortars of the basilica of San Lorenzo in Milan, which was carried out to support an archaeological study aimed at dating and documenting the construction techniques used throughout the centuries. The church, which was founded between the 4th and 5th century, at the end of the period when Milan was the capital of the Roman Empire, was subjected in time to extensions, collapses and reconstructions that lasted until the Renaissance period and even later on. Thanks to the good state of conservation, San Lorenzo church is a collection of materials and construction techniques throughout a period of more than a millennium. Mortars were investigated in order to compare the binders used for structural elements built in different historical ages. From an archaeological study, samples of mortars attributed to the late Roman period, the Middle Ages and the Renaissance were available. The binder of each sample was separated by the aggregates and it was characterised on the basis of X-ray diffraction analysis, thermogravimetric analysis and scanning electron microscopy. Constituents of the binder were identified and their origin is discussed in order to investigate if they could be attributed to the original composition of the binder or to possible alteration in time due to atmospheric pollution. Results show that, even though the binder is mainly based on magnesian lime, there are significant differences in the microstructure of the binding matrix used in mortars ascribed to the different historical periods. In the Roman period, in correspondence of the structural elements that required higher strength, also hydraulic cocciopesto mortars were detected. Gypsum was found in most samples, which was maybe added intentionally. - Highlights: • Binders of mortars of San Lorenzo church in Milan were investigated. • Roman, Middle Ages and Renaissance samples were studied by XRD, TG and SEM. • Magnesian-lime binders containing silico

  19. Organisation and Management of a Complete Bachelor Degree Offered Online at the University of Milan for Ten Years

    Science.gov (United States)

    Milani, Manuela; Papini, Sabrina; Scaccia, Daniela; Scarabottolo, Nello

    2014-01-01

    This paper is aimed at presenting some reflections on organisation and management of SSRI online: an e-learning initiative started at the University of Milan (Italy) in the academic year 2004/05 and offered to students over the last ten years. The initiative consisted in implementing the online version of an already existing three-year bachelor…

  20. Materials for the history of the Ospedale Maggiore of Milan: the Chapter resolutions of the years 1456-1498

    Directory of Open Access Journals (Sweden)

    Giuliana Albini

    2011-04-01

    Full Text Available The history of charity and assistance in Milan at the end of the Middle Ages has as basic term of reference the documentary sources of the Ospedale Maggiore, the new great hospital result of a long process of reform that took place in the course of the 15th century. The Chapter of the Ospedale Maggiore became a management centre which planned and controlled the activities of other charitable-attendance structures, the most important of them represented in the corporative administrative body of the Ospedale Maggiore itself. The Ospedale Maggiore Chapter left evidence of its meetings and decisions in more than 3000 proceedings, registered in seven records. The board resolutions of the Ospedale Maggiore of Milan are a basic source for the history of hospitals of all Lombardy. Moreover, they shed light on economic, social and political dynamics of the Duchy of Milan at the end of Quattrocento: the organization of the Ospedale Maggiore board highlights on politics and strategies of the ruling groups of Milan and of the Sforza dynasty as well. Object of this work is the edition, in the form of regestum, of the Ospedale Maggiore Chapter resolutions; a map of the country estate, land, farms, mills, of the Ospedale Maggiore, is edited too.

  1. Dr. Milan Glavinić, architect (Belgrade 1891 - Belgrade 1968: Addenda to the biography

    Directory of Open Access Journals (Sweden)

    Latinčić Olga

    2016-01-01

    Full Text Available The paper supplies further data for a biography of Milan Glavinić, such as information on his participation in the Balkan Wars and the First World War and his broad social and political activity. It also presents his published and unpublished texts on architecture, urban planning and art history, his 'Iskrice' (Sparks and his texts on old Belgrade kept in Glavinić Family Papers in the Historical Archives of Belgrade. His texts on old Belgrade are based on his own memories, the memories and stories told by his father Kosta and other people, and the surviving documents. They describe Belgrade's houses, their owners, prices, particular city districts, the Elementary School by the Cathedral, the Big Stairs, restaurants, and sketch his urban planning ideas.

  2. Blood pressure and 10-year mortality risk in the Milan Geriatrics 75+ Cohort Study

    DEFF Research Database (Denmark)

    Ogliari, Giulia; Westendorp, Rudi G J; Muller, Majon

    2015-01-01

    BACKGROUND: optimal blood pressure targets in older adults are controversial. OBJECTIVE: to investigate whether the relation of blood pressure with mortality in older adults varies by age, functional and cognitive status. DESIGN: longitudinal geriatric outpatient cohort. SETTING: Milan Geriatrics.......001 and 0.004, respectively). In patients with SBP below 180 mmHg, higher SBP was associated with lower mortality in patients with impaired ADL and MMSE but not in those with preserved ADL and/or MMSE (P for interaction 0.033). Age did not modify the correlation of SBP with mortality. CONCLUSIONS......: the correlations of SBP and DBP with mortality were U-shaped. Higher SBP is related to lower mortality in subjects with impaired ADL and MMSE. ADL and MMSE may identify older subjects who benefit from higher blood pressure....

  3. The meteor of the Neighbourhood Contracts through the case of the San Siro district in Milan

    Directory of Open Access Journals (Sweden)

    Maria Fianchini

    2012-10-01

    Full Text Available The study deals with the San Siro public housing neighbourhood in Milan, whose size and amount of issues make the district as a system in itself disjointed to the urban context. Features and conditions of this area, would require an hard work (and simultaneously offered great opportunities for researching and field-testing innovative solutions for building and social rehabilitation of the great public housing settlements, as originally outlined in the «Neighbourhood Contracts». On the contrary, funds assigned to this complex by the second competition for «Neighbourhood Contracts», doesn’t seem to have started any innovative process of intervention on built environment, but rather letting an involutional model.

  4. PAH and N-PAH in the urban atmosphere of Rome and Milan

    International Nuclear Information System (INIS)

    Cecinato, A.; Ciccioli, P.; Brancaleoni, E.; Zagari, M.

    1998-01-01

    Particulated PAH and nitrated-PAH (N-PAH) have been measured in urban areas of Rome and Milan to assess the exposure of the population to carcinogenic and mutagenic compounds. We found that the index of benz(a)pyrene equivalence of carcinogenic power and the levels of 1-nitropyrene and 2-nitro fluoranthene might represent a genotoxic risk for human health even when benz(a)pyrene does not exceed the reference levels established by Italian law. A new couple of indices (1-nitropyrene and 2-nitro fluoranthene content) is proposed to account for the risk arising from N-PAH emitted from vehicle exhaust gas or produced by photochemical reactions [it

  5. Contribution to fractal Analysis of cities : A Study of metropolitan Area of Milan

    Directory of Open Access Journals (Sweden)

    Rabino Giovanni

    2004-04-01

    Full Text Available La présentation de l'analyse fractale de l'aire métropolitaine de Milan part de la description historique de l'évolution du processus d'urbanisation de la ville, de manière à pouvoir mettre en évidence des zones précises, homogènes du point de vue historique, qui seront analysées dans la suite par le biais de la technique fractale. L'analyse fractale de la ville de Milan est menée selon trois approches : l'étude du périmètre de la ville, qui utilise la méthode de la dilatation pour extraire le périmètre et l'analyse de corrélation pour calculer sa dimension fractale ; l'étude de la surface urbanisée dans son ensemble, qui utilise l'analyse de corrélation, de dilatation et du quadrillage ; l'étude de certaines zones de la ville qui ont été décrites dans la première partie de la présentation ; les résultats sont présentés avec une attention particulière au rapport entre la valeur de la dimension fractale et le contexte urbain pour lequel elle est calculée, ainsi qu'à la comparaison des dimensions fractales des différentes zones urbaines prises en considération.

  6. Bacterial and fungal deterioration of the Milan Cathedral marble treated with protective synthetic resins

    Energy Technology Data Exchange (ETDEWEB)

    Cappitelli, Francesca [Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, University of Milan, Via Celoria 2, 20133 Milan (Italy)], E-mail: francesca.cappitelli@unimi.it; Principi, Pamela [Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, University of Milan, Via Celoria 2, 20133 Milan (Italy); Pedrazzani, Roberta [Dipartimento di Ingegneria Meccanica, University of Brescia, Via Branze 38, 25123 Brescia (Italy); Toniolo, Lucia [Dipartimento di Chimica, Materiali e Ingegneria Chimica ' Giulio Natta' , Politecnico di Milano, Via Mancinelli 7, 20133 Milan (Italy); Sorlini, Claudia [Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, University of Milan, Via Celoria 2, 20133 Milan (Italy)

    2007-10-15

    Surfaces are continuously exposed to physical, chemical and biological degradation. Among the biological agents that cause deterioration, microorganisms are of critical importance. This work is part of a research programme for the characterisation of the alterations of the Milan Cathedral (Italy). Four stone samples of the Milan Cathedral were chemically analysed and the microbiological growth assessed. X-ray diffraction (XRD) showed that calcite was always present in each sample and one sample was also characterised by the chemical form of alteration gypsum. Using Fourier Transform Infrared Spectroscopy (FTIR) together with Scanning Electron Microscopy (SEM), it was possible to prove that the samples were consolidated with the synthetic acrylics and epoxy resins. The green-black biological patinas of the specimens were studied using cultivation, microscope observations and a method for single-cell detection. Sampling for fluorescent in-situ hybridisation (FISH), with ribosomal RNA targeted oligonucleotide probes, was also performed using adhesive tapes. The bulk of the prokaryotes were Bacteria but some Archaea were also found. The bacterial cells were further characterised using specific probes for Cyanobacteria, and {alpha}-, {beta}-and {gamma}-Proteobacteria. In addition, black fungi isolated from the stone and the fungi of the standard ASTM G21-96(2002) method were employed to test if the detected synthetic resins could be used as the sole source of carbon and energy. One isolated Cladosporium sp. attacked the freshly dried acrylic resin. Results show that the detected bacteria and fungi can cause severe damage both to the stone monument and its synthetic consolidants.

  7. Bacterial and fungal deterioration of the Milan Cathedral marble treated with protective synthetic resins.

    Science.gov (United States)

    Cappitelli, Francesca; Principi, Pamela; Pedrazzani, Roberta; Toniolo, Lucia; Sorlini, Claudia

    2007-10-15

    Surfaces are continuously exposed to physical, chemical and biological degradation. Among the biological agents that cause deterioration, microorganisms are of critical importance. This work is part of a research programme for the characterisation of the alterations of the Milan Cathedral (Italy). Four stone samples of the Milan Cathedral were chemically analysed and the microbiological growth assessed. X-ray diffraction (XRD) showed that calcite was always present in each sample and one sample was also characterised by the chemical form of alteration gypsum. Using Fourier Transform Infrared Spectroscopy (FTIR) together with Scanning Electron Microscopy (SEM), it was possible to prove that the samples were consolidated with the synthetic acrylics and epoxy resins. The green-black biological patinas of the specimens were studied using cultivation, microscope observations and a method for single-cell detection. Sampling for fluorescent in-situ hybridisation (FISH), with ribosomal RNA targeted oligonucleotide probes, was also performed using adhesive tapes. The bulk of the prokaryotes were Bacteria but some Archaea were also found. The bacterial cells were further characterised using specific probes for Cyanobacteria, and alpha-, beta-and gamma-Proteobacteria. In addition, black fungi isolated from the stone and the fungi of the standard ASTM G21-96(2002) method were employed to test if the detected synthetic resins could be used as the sole source of carbon and energy. One isolated Cladosporium sp. attacked the freshly dried acrylic resin. Results show that the detected bacteria and fungi can cause severe damage both to the stone monument and its synthetic consolidants.

  8. Statistical methods and transport modeling to assess PCE hotspots and diffuse pollution in groundwater (Milan FUA

    Directory of Open Access Journals (Sweden)

    Loris Colombo

    2017-12-01

    Full Text Available The Italian law 152/2006 adopted the EU Water Framework Directive principles and delegated to the Regions the task of identifying areas subject to groundwater diffuse pollution. In the Lombardy Plain, the qualitative groundwater conditions are affected mainly by the presence of industries and anthropic activities. The aim of this work was to assess tetrachloroethylene (PCE diffuse pollution in the Milan Functional Urban Area (FUA, where chlorinated solvents are the main groundwater contaminants and the results of monitoring campaigns for the years 2003-2014 were collected in a dataset. For this purpose, a new methodology was implemented both in a deterministic and stochastic process. At first, hotspots were identified through Cluster Analysis (CA applied to concentration values collected in unconfined/confined aquifers (2003-14. Then, a numerical transport model was implemented to study the hotspot plume extension in reason to identify monitoring wells not affected by diffuse pollution but related to specific hotspot sources. Consequently, it was possible to erase these data from the whole initial dataset in order to have a new one containing only diffuse concentrations. Interpolating them through ordinary kriging, PCE iso-concentrations maps identified areas where values are over the Maximum Contaminant Level (1.1 μg/l, Italian Law 152/06. Considering descriptive statistics and iso-PCE concentration maps, a median PCE value estimation (10 μg/l was find as representative of PCE diffuse contamination Milan city. Moreover, a stochastic methodology was used in order to consider uncertainties due to unknown multiple-sources and environmental heterogeneity. The innovative approach gave some interesting solutions to point out areas where the contaminant mass release is higher and where high probability unknown sources can be found.

  9. Particle number and mass exposure concentrations by commuter transport modes in Milan, Italy

    Directory of Open Access Journals (Sweden)

    Senem Ozgen

    2016-03-01

    Full Text Available There is increasing awareness amongst the general public about exposure to atmospheric pollution while travelling in urban areas especially when taking active travelling modes such as walking and cycling. This study presents a comparative investigation of ultrafine particles (UFP, PM10, PM2.5, PM1 exposure levels associated with four transport modes (i.e., walking, cycling, car, and subway in the city of Milan measured by means of portable instruments. Significant differences in particle exposure between transport modes were found. The subway mode was characterized by the highest PM mass concentrations: PM10, PM2.5, PM1 subway levels were respectively about 2-4-3 times higher than those of the car and open air active modes (i.e. cycling and walking. Conversely, these latter modes displayed the highest UFP levels about 2 to 3 times higher than the subway and car modes, highlighting the influence of direct traffic emissions. The car mode (closed windows, air conditioning and air recirculation on reported the lowest PM and UFP concentration levels. In particular, the open-air/car average concentration ratio varied from about 2 for UFP up to 4 for PM1 and 6 for PM10 and PM2.5, showing differences that increase with increasing particle size. This work points out that active mode travelling in Milan city centre in summertime results in higher exposure levels than the car mode. Walkers’ and cyclists’ exposure levels is expected to be even higher during wintertime, due to the higher ambient PM and UFP concentration. Interventions intended to re-design the urban mobility should therefore include dedicated routes in order to limit their exposure to PM and UFP by increasing their distance from road traffic.

  10. The area of "Porta Vittoria” in Milan L'area “Porta Vittoria” a Milano

    Directory of Open Access Journals (Sweden)

    Fulvia Pinto

    2011-02-01

    Full Text Available The transformation of Milan, to be realized completely, needs of transport infrastructure as well as major European cities. The Rail “Passante” is a trasport infrastructure almost entirely underground and it crosses the city of Milan from north-west to south-east. The "Passante" represents the structure on which to build the urban development of the "Greater Milan" and plays a strategic role in the choice of location, facilitating the creation of an urban system integrated and competitive. The "Passante" connects the central parts of the city with suburbs that are already taking advantage of the presence of the infrastructure to renew their image. The study area was originally occupied by a station of the State Railways, now is a new station of the railway "Passante". The context of urban transformation "Porta Vittoria" is located in a central area of Milan, just beyond the first “circumvallazione”, on the connecting axis the airport of Linate. The strategic location of the area, very accessible, has determined the choice of the functions that must be kept. The regeneration is characterized by two important projects, one public and one private. The public intervention concerns the BEIC - European Library of Information and Culture, the private action relates to the new district "Porta Vittoria", with mixed-use residences, offices, malls, hotels and cinemas. The project for the European Library of Information and Culture, developed many years ago, intended to give Milan an "infrastructure" for culture considered the largest of Europe. The lack of funding has led to long interruptions and long delays in implementation. The project pays particular attention to the sustainability of the building, using energy energy-efficient systems with heat pumps (with exploiting groundwater, rather superficial in that area, solar collectors and photovoltaic panels. The hypothesis expresses the desire to create a relationship between the winning project

  11. Final method evaluation: development of spatially resolved emission inventories for Milan and Athens

    International Nuclear Information System (INIS)

    Winiwarter, W.; Vlachogiannis, D.; Gounaris, N.; Bartzis, J.; Ekstrand, S.; Tamponi, M.; Licotti, C.; Maffeis, G.; Dore, C.; Hayman, G.

    2001-10-01

    Emission inventories have been prepared for the Milan province, Italy, and for the greater Athens area, Greece using the methodology developed and refined in earlier work packages of the EC-funded IMPRESAREO project. Emission totals have been spatially-disaggregated onto a 1x1 km 2 grid CORINE land-cover data derived from earth observation (EO) was used as the main input for distributing the emission totals (taken as the totals of the bottom-up inventory). As in the earlier applications of the IMPRESAREO methodology, additional non-EO information was included to improve the spatial disaggregation - this was specifically census data, the road network and traffic counts, and centrally available data on point source emissions. Emission inventories for Milan were generated for three compounds (NO x , NMVOC and CO), while emission inventories of SO 2 and CO 2 were prepared for Athens in addition to these three pollutants. Distributing emissions to the respective land use type was based on the use of 'emission weighting factors' which had been derived in previous work packages of the IMPRESAREO project. The resulting top-down inventories were compared to the existing bottom up inventories using a number of quantitative and qualitative methods, which had been developed during previous stages of the project, or newly developed here. The results prove that the IMPRESAREO methodology provides useful emission inventories. The needs of a user can be taken to steer the effort (and the costs) which have to be put into the inventory. Tables are provided that describe the return in number of 'acceptable' grid cells depending on the detail level of the inventory. Also, the high importance of the traffic grid to a map representation of the inventory is shown, and the influence single point sources may have on the overall emission total, even of an urban region, is indicated. For environmental assessment purposes, this emphasises the need for a proper assessment of these point source

  12. The temporary structures for Expo Milan 2015: environmental assessment and solutions for the end of life management

    Directory of Open Access Journals (Sweden)

    Monica Lavagna

    2014-05-01

    Full Text Available Politecnico di Milano University worked for the Italian Ministry of Environment, land and sea on the sustainability assessment of Expo Milan 2015 self-built temporary pavilions. The work has been focused on the improvement of the buildings environmental performances. Given the buildings short durability in place (Expo lasts for 6 months, the strategies for their end of life are of great importance for the carbon footprint reduction. Starting from the specific work on Expo Milan 2015, the Politecnico di Milano working group proceeded with the methodology research about this issue, applicable also to future events. This paper presents the different relevant aspects of mega events temporary buildings end of life management; dealing with methodological, technical and managerial aspects.

  13. Numerical models of pore pressure and stress changes along basement faults due to wastewater injection: Applications to the 2014 Milan, Kansas Earthquake

    Science.gov (United States)

    Hearn, Elizabeth H.; Koltermann, Christine; Rubinstein, Justin R.

    2018-01-01

    We have developed groundwater flow models to explore the possible relationship between wastewater injection and the 12 November 2014 Mw 4.8 Milan, Kansas earthquake. We calculate pore pressure increases in the uppermost crust using a suite of models in which hydraulic properties of the Arbuckle Formation and the Milan earthquake fault zone, the Milan earthquake hypocenter depth, and fault zone geometry are varied. Given pre‐earthquake injection volumes and reasonable hydrogeologic properties, significantly increasing pore pressure at the Milan hypocenter requires that most flow occur through a conductive channel (i.e., the lower Arbuckle and the fault zone) rather than a conductive 3‐D volume. For a range of reasonable lower Arbuckle and fault zone hydraulic parameters, the modeled pore pressure increase at the Milan hypocenter exceeds a minimum triggering threshold of 0.01 MPa at the time of the earthquake. Critical factors include injection into the base of the Arbuckle Formation and proximity of the injection point to a narrow fault damage zone or conductive fracture in the pre‐Cambrian basement with a hydraulic diffusivity of about 3–30 m2/s. The maximum pore pressure increase we obtain at the Milan hypocenter before the earthquake is 0.06 MPa. This suggests that the Milan earthquake occurred on a fault segment that was critically stressed prior to significant wastewater injection in the area. Given continued wastewater injection into the upper Arbuckle in the Milan region, assessment of the middle Arbuckle as a hydraulic barrier remains an important research priority.

  14. [Voluntary mediation in healthcare disputes: the experience of the "Fondazione IRCCS Istituto Nazionale dei Tumori" in Milan (Italy)].

    Science.gov (United States)

    Tereanu, Carmen; Bettega, Silvia; Regalia, Enrico; Mazza, Roberto; Greco, Margherita; Lozza, Laura; Saita, Luigi; Borreani, Claudia; Quattrocolo, Alberto

    2014-01-01

    The "Fondazione IRCCS Istituto Nazionale dei Tumori" ( National Tumour Institute) in Milan (Italy) offers mediation services aimed at restoring communication between patients and healthcare professionals, when their relationship has been altered by a conflict during the diagnosis or treatment process. A method derived from transformative mediation is used. The purpose of mediation is not to examine clinical aspects, nor to identify who is right and who is wrong. Individual sessions are often sufficient to reduce litigation.

  15. Adverse biological effects of Milan urban PM looking for suitable molecular markers of exposure

    Directory of Open Access Journals (Sweden)

    Mantecca Paride

    2012-01-01

    Full Text Available The results presented summarise the ones obtained in the coordinated research project Tosca, which extensively analysed the impact of Milan urban PM on human health. The molecular markers of exposure and effects of seasonally and size-fractionated PMs (summer and winter PM10, PM2.5 were investigated in in vitro (human lung cell lines and in vivo (mice systems. The results obtained by the analyses of cytotoxic, pro-inflammatory and genotoxic parameters demonstrate that the biological responses are strongly dependent upon the PM samples seasonal and dimensional variability, that ultimately reflect their chemical composition and source. In fact summer PM10, enriched in crustal elements and endotoxins, was the most cytotoxic and pro-inflammatory fraction, while fine winter PMs induced genotoxic effects and xenobiotic metabolizing enzymes (like CYP1B1 production, likely as a consequence of the higher content in combustion derived particles reach in PAHs and heavy toxic metals. These outcomes outline the need of a detailed knowledge of the PMs physico-chemical composition on a local scale, coupled with the biological hazard directly associated to PM exposure. Apparently this is the only way allowing scientists and police-makers to establish the proper relationships between the respirable PM quantity/quality and the health outcomes described by clinicians and epidemiologists.

  16. Mobile Applications as Tool for Exploiting Cultural Heritage in the Region of Turin and Milan

    Science.gov (United States)

    Rolando, A.; Scandiffio, A.

    2013-07-01

    visualization of data flows. In the current research, the field of investigation refers both to the territorial scale of Turin - Milan axis, and to the local scale of small cities localized in the territories in between. The research has been applied to Turin - Milan infrastructural axis, with the aim to represent the relationships that can be established between mobility infrastructure and cultural heritage. Such relationships should be intended in terms of accessibility from mobility infrastructure (motorway exit, service areas, railways stations) to cultural heritage localized in the surrounding landscape. The richness of cultural heritage and landscape along the chosen infrastructural bundle represent a great opportunity for territorial development in terms of attractiveness, both for local inhabitants and for tourists. Nowadays, the use of tracking technologies can be applied to investigate tourist flows, behaviors of local inhabitants in the historic city centre, number of visitors in the city and so on. In this sense it is possible to apply these technologies, which are particularly relevant in urban studies, extending them to the territorial scale of the Turin - Milan region. The large amount of available geo-referenced data can be used in different ways and it is very potential for different kind of analysis: it is possible to show tourist flows in the territory, receive information about more visited places, obtain interaction from users and cultural heritage in terms of visitors opinion about the places, give information to tourists about cultural places, monitor the accessibility to the places, understand the use of means of transport and keep under control the impacts of tourism (social, cultural, environmental) on territory. Applications based on smartphones can be considered a powerful device for visitors but also for institutions that are involved in tourism and cultural heritage management. In fact, the use of mobile applications it can produce a real time data

  17. Aerosol removal due to precipitation and wind forcings in Milan urban area

    Science.gov (United States)

    Cugerone, Katia; De Michele, Carlo; Ghezzi, Antonio; Gianelle, Vorne

    2018-01-01

    Air pollution represents a critical issue in Milan urban area (Northern Italy). Here, the levels of fine particles increase, overcoming the legal limits, mostly in wintertime, due to favourable calm weather conditions and large heating and vehicular traffic emissions. The main goal of this work is to quantify the aerosol removal effect due to precipitation at the ground. At first, the scavenging coefficients have been calculated for aerosol particles with diameter between 0.25 and 3 μm. The average values of this coefficient vary between 2 ×10-5 and 5 ×10-5 s-1. Then, the aerosol removal induced separately by precipitation and wind have been compared through the introduction of a removal index. As a matter of fact, while precipitation leads to a proper wet scavenging of the particles from the atmosphere, high wind speeds cause enhanced particle dispersion and dilution, that locally bring to a tangible decrease of aerosol particles' number. The removal triggered by these two forcings showed comparable average values, but different trends. The removal efficiency of precipitation lightly increases with the increase of particle diameters and vice versa happens with strong winds.

  18. Corrosion assessment of reinforced concrete elements of Torre Velasca in Milan

    Directory of Open Access Journals (Sweden)

    Federica Lollini

    2016-06-01

    Full Text Available An assessment of corrosion conditions, aimed at the detection of the most suitable intervention method, of the reinforced concrete elements of Torre Velasca, which, from the late 1950s, characterises the skyline of the city centre of Milan, was carried out. The facades of the Tower are marked by the presence of structural elements coated with thick and dense layers of render and mortar. In-situ and laboratory analyses showed that the high thickness and compactness of the coating played a positive role in preventing the propagation of carbonation and of corrosion. It was estimated that after 50 years most rebars embedded in concrete were either still passive or free from actively-propagating corrosion. Hence it was concluded that most of the original concrete and coating could be preserved without further protection. However, this repair strategy could be compromised by the risk of loss of adhesion of the coating to the underlying concrete, and this crucial aspect should be better investigated in the design of the repair work.

  19. Computer aided instruction. Preliminary experience in the Radiological Sciences Institute of the University of Milan

    International Nuclear Information System (INIS)

    Gardani, G.; Bertoli, M.A.; Bellomi, M.

    1987-01-01

    Computerised instruction means teaching by computer using a program that alternates information with self-checking multiple choice questions. This system was used to create a fully computerized lesson on the diagnosis and treatment of breast cancer which was then tested on a small group of madical students attending the Radiology School of the Milan University Institute of Radiological Sciences. At the end of the test, the students were asked to complete a questionnaire which was then analysed. The computer lesson consisted of 66 text messages and 21 self-checking questions. It aroused considerable interest, though the most common reason was curiosity about a novel system. The degree of fatigue caused was modest despite the fact that the computer lesson was at least as demanding as a traditional lesson, if not more so. The level of learning was considered high and optimised by the use of self-checking questions that were considered an essential element. However no student agreed to sit an official examination, even interactively, using the computer

  20. MOBILE APPLICATIONS AS TOOL FOR EXPLOITING CULTURAL HERITAGE IN THE REGION OF TURIN AND MILAN

    Directory of Open Access Journals (Sweden)

    A. Rolando

    2013-07-01

    , analysis and visualization of data flows. In the current research, the field of investigation refers both to the territorial scale of Turin – Milan axis, and to the local scale of small cities localized in the territories in between. The research has been applied to Turin – Milan infrastructural axis, with the aim to represent the relationships that can be established between mobility infrastructure and cultural heritage. Such relationships should be intended in terms of accessibility from mobility infrastructure (motorway exit, service areas, railways stations to cultural heritage localized in the surrounding landscape. The richness of cultural heritage and landscape along the chosen infrastructural bundle represent a great opportunity for territorial development in terms of attractiveness, both for local inhabitants and for tourists. Nowadays, the use of tracking technologies can be applied to investigate tourist flows, behaviors of local inhabitants in the historic city centre, number of visitors in the city and so on. In this sense it is possible to apply these technologies, which are particularly relevant in urban studies, extending them to the territorial scale of the Turin – Milan region. The large amount of available geo-referenced data can be used in different ways and it is very potential for different kind of analysis: it is possible to show tourist flows in the territory, receive information about more visited places, obtain interaction from users and cultural heritage in terms of visitors opinion about the places, give information to tourists about cultural places, monitor the accessibility to the places, understand the use of means of transport and keep under control the impacts of tourism (social, cultural, environmental on territory. Applications based on smartphones can be considered a powerful device for visitors but also for institutions that are involved in tourism and cultural heritage management. In fact, the use of mobile applications it can

  1. Surveillance of Mosquitoes and Selected Arthropod-Borne Viruses in the Context of Milan EXPO 2015

    Directory of Open Access Journals (Sweden)

    Mario Chiari

    2016-07-01

    Full Text Available From 1 May 2015 to 31 October 2015 over 20 million visitors from all over the world visited the Universal Exhibition (EXPO hosted by Milan (Lombardy region, Italy, raising concerns about the possible introduction of mosquito-borne diseases from endemic countries. The entomological surveillance protocol performed in Lombardy over the last three years was implemented in the EXPO area and in the two major regional airports using both Center for Disease Control CO2 and Biogents Sentinel traps. This surveillance aimed to estimate the presence and densities of putative vectors, and also to support investigations, including the vector species involved and area of diffusion, on the local spread of Chikungunya, Dengue and West Nile viruses (WNV by competent vectors. From 3544 mosquitoes belonging to five different species, 28 pools of Culex spp. and 45 pools of Aedes spp. were screened for the presence of WNV, and for both Chikungunya and flaviviruses, respectively. The entomological surveillance highlighted a low density of potential vectors in the surveyed areas and did not reveal the presence of Chikungunya or Dengue viruses in the local competent vectors inside the EXPO area or in the two airports. In addition, the surveillance reported a low density of Culex spp. mosquitoes, which all tested negative for WNV.

  2. Monitoring emerging contaminants in the drinking water of Milan and assessment of the human risk.

    Science.gov (United States)

    Riva, Francesco; Castiglioni, Sara; Fattore, Elena; Manenti, Angela; Davoli, Enrico; Zuccato, Ettore

    2018-01-16

    Emerging Contaminants (ECs) are ubiquitous in waters, arousing concern because of their potential risks for human health and the environment. This study investigated the presence of multiple classes of ECs in 21 wells over the drinking water network of Milan, in the most inhabited and industrialized area of Italy, and assessed the risks for consumers. Samples were analyzed using liquid chromatography coupled to mass spectrometry. Human risk assessment (HRA) was conducted by comparing the measured concentrations with drinking water thresholds from guidelines or calculated in this study; first considering the exposure to each single EC and then the entire mixture. Thirteen ECs were measured in the low ng/L range, and were generally detected in less than half of the wells. Pharmaceuticals, perfluorinated substances, personal care products, and anthropogenic markers were the most frequently detected. The results of the HRA excluded any risks for consumers in each scenario considered. This is one of the most comprehensive studies assessing the presence of a large number of ECs in the whole drinking water network of a city, and the risks for human health. Results improve the limited information on ECs sources and occurrence in drinking water and help establishing guidelines for regulatory purposes. Copyright © 2018 Elsevier GmbH. All rights reserved.

  3. Entre o passado e o presente do romance moderno: o humor na escrita de Milan Kundera

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    Wilton Barroso Filho

    2015-07-01

    Full Text Available Resumo: Enquanto pensador da criação estético-romanesca, Milan Kundera assegura que, para refletir acerca da “Arte do Romance” e aquilo que dela se extrai como conhecimento é indispensável procurar entendê-la a partir de dentro de sua própria história; e para ele, quem começou a puxar os fios que teceriam essa história ao longo da modernidade fora o século XVI com François Rabelais. Sendo assim, procurando interpolar o passado ao presente do romance moderno, o humor kunderiano dialoga com a gaiatice do riso rabelaisiano. Entender em que medida esse diálogo permite ao romancista contemporâneo questionar as estruturas sociais bem como a autonomia da criação estética frente ao mundo dominado pela ditadura do idílio, constitui-se no objetivo central desse artigo.

  4. PAH and N-PAH in the urban atmosphere of Rome and Milan

    Energy Technology Data Exchange (ETDEWEB)

    Cecinato, A.; Ciccioli, P.; Brancaleoni, E.; Zagari, M. [CNR, Monterotondo Scalo, Rome (Italy). Ist. sull`Inquinamento Atmosferico

    1998-05-01

    Particulated PAH and nitrated-PAH (N-PAH) have been measured in urban areas of Rome and Milan to assess the exposure of the population to carcinogenic and mutagenic compounds. We found that the index of benz(a)pyrene equivalence of carcinogenic power and the levels of 1-nitropyrene and 2-nitro fluoranthene might represent a genotoxic risk for human health even when benz(a)pyrene does not exceed the reference levels established by Italian law. A new couple of indices (1-nitropyrene and 2-nitro fluoranthene content) is proposed to account for the risk arising from N-PAH emitted from vehicle exhaust gas or produced by photochemical reactions. [Italiano] I PAH e i N-PAH particellari sono stati misurati nelle aree urbane di Milano e Roma per valutare l`esposizione delle popolazioni a specie cancerogeniche e mutageniche. I risultati indicano che l`indice di equivalenza di potere cancerogeno riferita al benz(a)pirene ed i livelli di 1-nitropirene e 2-nitrofluorantene possono rappresentare un rischio genotossico per la salute umana anche quando il benz(a)pirene non supera i livelli di riferimento stabiliti dal Ministero dell`Ambiente. E` proposta l`assunzione di una nuova coppia di indici (contenuto di 1-nitropirene e 2-nitrofluorantene) per valutare la mutagenicita` associata alle emissioni autoveicolari o alla reattivita` fotochimica.

  5. Suicide Risk and the Economic Crisis: An Exploratory Analysis of the Case of Milan.

    Science.gov (United States)

    Merzagora, Isabella; Mugellini, Giulia; Amadasi, Alberto; Travaini, Guido

    2016-01-01

    In the past five years, several scientific articles have claimed that the increase some countries have registered in suicide rates since 2008 is somehow related to the economic crisis. Other research has suggested that the impact of specific economic problems on the probability of suicidal behavior is often mediated by other individual-level factors, mainly psychological and physical, whose negative influence is exacerbated by reductions in the availability of health and social care during an economic crisis. On the basis of almost 1,000 cases of suicide collected by the Institute of Forensic Medicine in the province of Milan, this article aims at testing whether suicidal probability during an economic crisis is influenced by the interaction between an individual's employment status and the presence of psychological or physical disease. Using a binary logistic regression model, this article demonstrates that the likelihood of suicide during an economic crisis is three times higher for persons affected by a severe disease, either physical or psychological, than for people who are not affected (OR = 3.156; 95% CI = 1.066-9.339; p = 0.38). Neither employment status nor the interaction between employment status and health status contributed to the difference between the suicide rate before and during the economic crisis.

  6. Hourly composition of gas and particle phase pollutants at a central urban background site in Milan, Italy

    Science.gov (United States)

    Bigi, A.; Bianchi, F.; De Gennaro, G.; Di Gilio, A.; Fermo, P.; Ghermandi, G.; Prévôt, A. S. H.; Urbani, M.; Valli, G.; Vecchi, R.; Piazzalunga, A.

    2017-04-01

    A comprehensive range of gas and particle phase pollutants were sampled at 1-hour time resolution in urban background Milan during summer 2012. Measurements include several soluble inorganic aerosols (Cl-, NO2-, NO3-, SO42-, Ca2+, K+, Mg2+, Na+, NH4+) and gases (HCl, HNO2,HNO3, NH3, NO, NO2,O3, SO2), organic, elemental and black carbon and meteorological parameters. Analysis methods used include mean diurnal pattern on weekdays and Sundays, pollution roses, bivariate polar plots and statistical models using backtrajectories. Results show how nitrous acid (HONO) was mainly formed heterogeneously at nighttime, with a dependence of its formation rate on NO2 consistent with observations during the last HONO campaign in Milan in summer 1998, although since 1998 a drop in HONO levels occurred following to the decrease of its precursors. Nitrate showed two main formation mechanisms: one occurring through N2O5 at nighttime and leading to nitrate formation onto existing particles; another occurring both daytime and nighttime following the homogeneous reaction of ammonia gas with nitric acid gas. Air masses reaching Milan influenced nitrate formation depending on their content in ammonia and the timing of arrival. Notwithstanding the low level of SO2 in Milan, its peaks were associated to point source emissions in the Po valley or shipping and power plant emissions SW of Milan, beyond the Apennines. A distinctive pattern for HCl was observed, featured by an afternoon peak and a morning minimum, and best correlated to atmospheric temperature, although it was not possible to identify any specific source. The ratio of primary-dominated organic carbon and elemental carbon on hourly PM2.5 resulted 1.7. Black carbon was highly correlated to elemental carbon and the average mass absorption coefficient resulted MAC = 13.8 ± 0.2 m2 g-1. It is noteworthy how air quality for a large metropolitan area, in a confined valley and under enduring atmospheric stability, is nonetheless

  7. Assessing Natural Background Levels of aquifers in the Metropolitan Area of Milan (Lombardy)

    Science.gov (United States)

    De Caro, Mattia; Crosta, Giovanni; Frattini, Paolo

    2016-04-01

    The European Water Framework Directive (WFD 2000/60/CE) requires Member States to evaluate the status of groundwater bodies in order to reach a good water quality for human consumption. One of the preliminary steps for defining the status of groundwater bodies consists in the definition and evaluation of the so-called Natural Background Levels (NBL). The NBL or Baseline level can be defined as "the range of concentration of a given element, isotope or chemical compound in solution, derived entirely from natural, geological, biological or atmospheric sources, under conditions not perturbed by anthropogenic activity" (Edmund and Shand, 2009). The qualitative analysis for a large area (ca 4500 Km2) of the Po Plain around the Milan Metropolitan area (Lombardy, Italy) is presented in this study. Despite the aquifers in the Milan metropolitan area are an incredible groundwater resource for a very large population (3.195.629 inhabitants in the metropolitan area, data at November 2014) and a highly industrialized area, a groundwater baseline characterization is still missing. In order to attain the hydro-geochemical characterization a complete geodatabase was built (120.655 chemical samples from 1980 to 2014). This database has been explored by classical and multivariate statistical analyses to provide relationships among the more influential lithological, hydrogeological and hydro-chemical variables. Finally, the NBLs of different chemical species which may be anthropogenic sensitive (Na, Cl, K, NO3, SO4, NH4, As, Fe, Cr, Fe, Mn, Zn) and for multiple aquifer bodies (phreatic, semi-confined and confined aquifer) are evaluated. Two different approaches are applied: the Pre-Selection method (BRIDGE, 2006) and the Component-Separation method. The first one (PS) consists in the exclusion of samples from the available dataset that could indicate human activities then deriving the NBL as the 90th percentile of the remaining data. The second one (CS) consists in the fitting of

  8. [Hygienic profile of the water in Milan swimming pools: a three-year comparative study].

    Science.gov (United States)

    Tesauro, M; Bianchi, A; Consonni, M; Bollani, M; Cesaria, M; Trolli, F Radice; Galli, M G

    2010-01-01

    The aim of this work was to determine whether swimming pool water quality in Milan from 2006 to 2008 was within the standards established by national and local Italian laws (Circolare Min. Sanità 128/71 and DGR 2552/2006). In 2006, 580 samples of water from public swimming pools were analyzed to determine the presence of heterotrophic counts at 37 degrees and total coliforms; pH, free chlorine and chloride of each sample were also measured. In the following years, water from both public and private swimming pools were examined to measure heterotrophic count at 22 degrees and 36 degrees, Escherichia coli, enterococci, Pseudomonas aeruginosa, Staphylococcus aureus, pH, free chlorine, and nitrates. The total number of analyses carried out in 2007 and 2008 was 2074 and 1532, respectively. In 2006, the extent of noncompliance of all swimming pools that was observed for both physical/chemical and microbiological parameters was 72.3%, which then decreased to 53.2% and 36.2% in 2007 and 2008, respectively. In particular with regard to the microbiological analysis, an increase of noncompliance based on at least one parameter was determined (7.1% in 2006 vs. 21.5% in 2007 and 22% in 2008). In contrast, a decrease of the extent of noncompliance based on at least one physical/chemical parameter was observed (from 68.1% in 2006 to 40.4% and 22.3% in 2007 and 2008, respectively). Interestingly, public swimming pools exceeded the legal limits of microbiological concentration more often than the private ones, whereas both types of swimming pools showed a decrease in noncompliance with regard to the physical/chemical parameters.

  9. Pelvic exenteration: ten-year experience at the European Institute of Oncology in Milan.

    Science.gov (United States)

    Maggioni, Angelo; Roviglione, Giovanni; Landoni, Fabio; Zanagnolo, Vanna; Peiretti, Michele; Colombo, Nicoletta; Bocciolone, Luca; Biffi, Roberto; Minig, Lucas; Morrow, C Paul

    2009-07-01

    Analyze morbidity and survival after pelvic exenteration (PE) of gynecological malignancies. We reviewed 106 consecutive patients with gynecologic malignancies who underwent PE from June 1996 to April 2007 at the Division of Gynecology, European Institute of Oncology (IEO), Milan. PE was performed for cancer of the cervix (62 patients), vagina (21 patients), vulva (9 patients), endometrium (9 patients), ovary (4 patients) and 1 uterine sarcoma. Mean age was 53.6 (30-78) years. 97% of the patients received radiotherapy before PE and 3 patients had PE as primary treatment. We performed 53 anterior, 48 total and 5 posterior PE. Median operation time, estimated blood loss and hospital stay were respectively 490 (200-780) minutes, 1240 (300-6500) ml and 21.6 (11-55) days. No residual tumor was left in 93% of the patients. Median follow-up was 22.3 (1.6-117) months. There were no post-operative deaths (<30 days from surgery) nor intra-operative mortality. Total morbidity rate was 66%; 48% of patients had early complications (<30 days after PE) whereas 52 patients (48.5%) had late complications; 70% of these occurred to the urinary tract and 25% were due to bowel occlusions or fistulas. Overall survival was 52%, 35%, 19% and 16% respectively for cervical, endometrial, vaginal and vulvar cancer. PE is a feasible technique with no post-operative mortality and high percentage of long-survivors, although the morbidity rate still remains significantly high. Careful patient selection, pre- and post-operative care and optimal surgical skills in a Gynecologic Oncologic Center are the cornerstones to further improve quality of life and survival for these patients.

  10. Milan PM1 induces adverse effects on mice lungs and cardiovascular system.

    Science.gov (United States)

    Farina, Francesca; Sancini, Giulio; Longhin, Eleonora; Mantecca, Paride; Camatini, Marina; Palestini, Paola

    2013-01-01

    Recent studies have suggested a link between inhaled particulate matter (PM) exposure and increased mortality and morbidity associated with cardiorespiratory diseases. Since the response to PM1 has not yet been deeply investigated, its impact on mice lungs and cardiovascular system is here examined. A repeated exposure to Milan PM1 was performed on BALB/c mice. The bronchoalveolar lavage fluid (BALf) and the lung parenchyma were screened for markers of inflammation (cell counts, tumor necrosis factor-α (TNF-α); macrophage inflammatory protein-2 (MIP-2); heme oxygenase-1 (HO-1); nuclear factor kappa-light-chain-enhancer of activated B cells p50 subunit (NFκB-p50); inducible nitric oxide synthetase (iNOS); endothelial-selectin (E-selectin)), cytotoxicity (lactate dehydrogenase (LDH); alkaline phosphatase (ALP); heat shock protein 70 (Hsp70); caspase-8-p18), and a putative pro-carcinogenic marker (cytochrome 1B1 (Cyp1B1)). Heart tissue was tested for HO-1, caspase-8-p18, NFκB-p50, iNOS, E-selectin, and myeloperoxidase (MPO); plasma was screened for markers of platelet activation and clot formation (soluble platelet-selectin (sP-selectin); fibrinogen; plasminogen activator inhibitor 1 (PAI-1)). PM1 triggers inflammation and cytotoxicity in lungs. A similar cytotoxic effect was observed on heart tissues, while plasma analyses suggest blood-endothelium interface activation. These data highlight the importance of lung inflammation in mediating adverse cardiovascular events following increase in ambient PM1 levels, providing evidences of a positive correlation between PM1 exposure and cardiovascular morbidity.

  11. Milan PM1 Induces Adverse Effects on Mice Lungs and Cardiovascular System

    Directory of Open Access Journals (Sweden)

    Francesca Farina

    2013-01-01

    Full Text Available Recent studies have suggested a link between inhaled particulate matter (PM exposure and increased mortality and morbidity associated with cardiorespiratory diseases. Since the response to PM1 has not yet been deeply investigated, its impact on mice lungs and cardiovascular system is here examined. A repeated exposure to Milan PM1 was performed on BALB/c mice. The bronchoalveolar lavage fluid (BALf and the lung parenchyma were screened for markers of inflammation (cell counts, tumor necrosis factor-α (TNF-α; macrophage inflammatory protein-2 (MIP-2; heme oxygenase-1 (HO-1; nuclear factor kappa-light-chain-enhancer of activated B cells p50 subunit (NFκB-p50; inducible nitric oxide synthetase (iNOS; endothelial-selectin (E-selectin, cytotoxicity (lactate dehydrogenase (LDH; alkaline phosphatase (ALP; heat shock protein 70 (Hsp70; caspase-8-p18, and a putative pro-carcinogenic marker (cytochrome 1B1 (Cyp1B1. Heart tissue was tested for HO-1, caspase-8-p18, NFκB-p50, iNOS, E-selectin, and myeloperoxidase (MPO; plasma was screened for markers of platelet activation and clot formation (soluble platelet-selectin (sP-selectin; fibrinogen; plasminogen activator inhibitor 1 (PAI-1. PM1 triggers inflammation and cytotoxicity in lungs. A similar cytotoxic effect was observed on heart tissues, while plasma analyses suggest blood-endothelium interface activation. These data highlight the importance of lung inflammation in mediating adverse cardiovascular events following increase in ambient PM1 levels, providing evidences of a positive correlation between PM1 exposure and cardiovascular morbidity.

  12. a Comprehensive Study of the Milan Urban Plume: Gas Phase, Aerosols and ROG/NOx-SENSITIVITY

    Science.gov (United States)

    Dommen, J.; Bärtsch-Ritter, N.; Andreani-Aksoyoglu, S.; Keller, J.; Prevot, A. S. H.

    2003-04-01

    Three-dimensional photochemical models were used to investigate the temporal and spatial dynamics of the photooxidant and aerosol production in the highly polluted Milan area (Italy). A simulation of the 13 May, 1998 event is presented, when peak ozone levels of 190 ppb were measured in the urban plume. The model base case is able to reproduce the ozone concentration in the center of the plume but more peroxide is formed than in the adjacent areas in contradiction to observation. This can be interpreted as a tendency of the model towards a stronger NOx sensitivity compared to observation. The emission inventory was modified based on experimental evidence. Ozone levels did not differ much between the base case simulation and those with a modified emission inventory, while peroxide formation and NOx concentrations in the urban plume did. That lead to a better agreement with measurements. Based on this measurement-model comparison we studied the ROG/NOx sensitivity of the ozone production in this area. We also investigated the effects of various meteorological conditions and the resolution of the emission inventory on the ozone mixing ratio and the ROG/NOx sensitivity. It was found, that the net ozone formation in northern Italy depends stronger on temperature than humidity, while the humidity is more important for the ROG/NOx sensitivity of the ozone production. NOx sensitive areas increase only if much coarser emission inventories were used. Higher wind speeds increased ROG sensitive areas. The influence of strong point emission source was also investigated. The study was then extended to the calculation of secondary aerosol species such as particulate nitrate, ammonium, sulfate, and SOC (secondary organic carbon) for the particle sizes below 2.5 µm. The comparison between model results and observations will be presented and discussed.

  13. From groundwater baselines to numerical groundwater flow modelling for the Milan metropolitan area

    Science.gov (United States)

    Crosta, Giovanni B.; Frattini, Paolo; Peretti, Lidia; Villa, Federica; Gorla, Maurizio

    2015-04-01

    Contamination of major aquifers in highly densely populated areas is a major concern for stakeholders involved in the use and protection of groundwater resources. Sustainable groundwater withdrawal and management, and the identification of trends in groundwater contamination require a careful hydrochemical baseline characterization. This characterization is fundamental to investigate the presence and evolutionary trend of contaminants. In fact, it allows recovering and understanding: the spatial-temporal trend of contamination; the relative age of the contamination episodes; the reasons for anomalous behavior of some compounds during migration to and in the groundwater; the associations with which some contaminants can be found; the different behaviors in phreatic and semi-confined and confined aquifers. To attain such a characterization for the Milan metropolitan area (about 2,500 km2, ca 4.000.000 inhabitants, Lombardy, Italy), we carried out three main activities. (1) Collection of complete and reliable datasets concerning the geological, hydrogeological and hydrochemical (over 60,000 chemical analysis since 2003 to 2013) characteristics of the area and of the involved aquifers. This activity was very demanding because the available data are provided by different authorities (Lombardy Region, Provinces, Lombardy Environmental Agency - ARPA Lombardia, public own companies in charge of water system managements) in raw format and with different database standard, which required a large effort of manual verification and harmonization. (2) Completion of a hydrochemical characterization of the metropolitan area aquifers by classical statistical and multivariate statistical analyses, in order to define a baseline both for some major physical chemical characteristics and for the most relevant contaminants. (3) Development of a three dimensional hydrogeological model for the metropolitan area starting from the above listed datasets and existing models. This model will

  14. The medical malpractice in Milan-Italy. A retrospective survey on 14 years of judicial autopsies.

    Science.gov (United States)

    Casali, Michelangelo Bruno; Mobilia, Francesca; Sordo, Sara Del; Blandino, Alberto; Genovese, Umberto

    2014-09-01

    The medical malpractice is a rising and central topic for the forensic pathologist and forensic autopsies are a mandatory step in the judicial evaluation of the suspected medical malpractice. Reliable national and international registers about the medical malpractice are still missing and nowadays the necroscopic archives are therefore one of the best sources of data about such a complex phenomenon. We analyzed the archive of the Institute of Forensic Medicine of the Milan University from 1996 to 2009 and selected 317 lethal cases of suspected medical malpractice. The mean age of our cases was 60±18 years for males and 58±19 years for the females. In 70% of such cases the patient death occurred in a hospital setting. The first 24h of hospitalization turned out to be the hottest period for deaths followed by malpractice claims. The surgical branches were obviously the most involved, with abdominal surgery, orthopedics, neurosurgery and gynecology as the main contributors. Just 12% of the total amount of cases came from all the internistic branches put together. Non-hospital malpractice was typically caused by misdiagnosed myocardial infarctions and aortic ruptures. A full forensic report was present in 71 cases (all belonging to the 2007-2009 period): in 69% of cases the judicial autopsy revealed as a sufficient tool for diagnosing the cause of death; medical malpractice was confirmed in only 17% of the whole cases and a causal link between the ascertained malpractice and the patient death was recognized in only 12.7% cases. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  15. Hydrogeochemical characterization and Natural Background Levels in urbanized areas: Milan Metropolitan area (Northern Italy)

    Science.gov (United States)

    De Caro, Mattia; Crosta, Giovanni B.; Frattini, Paolo

    2017-04-01

    Although aquifers in densely populated and industrialized areas are extremely valuable and sensitive to contamination, an estimate of the groundwater quality status relative to baseline conditions is lacking for many of them. This paper provides a hydrogeochemical characterization of the groundwater in the Milan metropolitan area, one of the most densely populated areas in Europe. First, a conceptual model of the study area based on the analysis of the spatial distribution of natural chemical species and indicator contaminants is presented. The hydrochemical facies of the study area depend on the lithology of catchments drained by the main contributing rivers and on the aquifer settings. The anthropogenic influence on the groundwater quality of superficial aquifers is studied by means of probability plots, concentration versus depth plots and spatial-temporal plots for nitrate, sulfate and chloride. These allow differentiation of contaminated superficial aquifers from deep confined aquifers with baseline water quality. Natural Background Levels (NBL) of selected species (Cl, Na, NH4, SO4, NO3, As, Fe, Mn and Zn) are estimated by means of the pre-selection (PS) and the component separation (CS) statistical approaches. The NBLs depend on hydrogeological settings of the study area; sodium, chloride, sulfate and zinc NBL values never exceed the environmental water quality standards. NBL values of ammonium, iron, arsenic and manganese exceed the environmental water quality standards in the anaerobic portion of the aquifers. On the basis of observations, a set of criteria and precautions are suggested for adoption with both PS and CS methods in the aquifer characterization of highly urbanized areas.

  16. Seasonal variations in chemical composition and in vitro biological effects of fine PM from Milan.

    Science.gov (United States)

    Perrone, Maria Grazia; Gualtieri, Maurizio; Ferrero, Luca; Lo Porto, Claudia; Udisti, Roberto; Bolzacchini, Ezio; Camatini, Marina

    2010-03-01

    Fine particulate matter (PM1 and PM2.5) was collected in Milan over the summer (August-September) and winter (January-March) seasons of 2007/2008. Particles were analyzed for their chemical composition (inorganic ions, elements and PAHs) and the effects produced on the human lung carcinoma epithelial cell line A549. In vitro tests were performed to assess cell viability with MTT assay, cytokine release (IL-6 and IL-8) with ELISA, and DNA damage with COMET assay. Results were investigated by bivariate analysis and multivariate data analysis (Principal Component Analysis, PCA) to investigate the relationship between PM chemical composition and the biological effects produced by cell exposure to 12 microg cm(-2). The different seasonal chemical composition of PM showed to influence some biological properties. Summer PM samples had a high mass contribution of SO(4)(=) (13+/-2%) and were enriched in some elements, like Al, As, Cr, Cu, and Zn, compared to winter PM samples. Cell viability reduction was two times higher for summer PM samples in comparison with winter ones (27+/-5% and 14+/-5%, respectively), and the highest correlation coefficients between cell viability reduction and single chemical components were with As (R(2)=0.57) and SO(4)(=) (R(2)=0.47). PM1 affected cell viability reduction and induced IL-8 release, and these events were interrelated (R(2)=0.95), and apparently connected with the same chemical compounds. PM2.5 fraction, which was enriched in Ca(++) and Mg(++) (from soil dust), and Al, Fe, Zn, Ba Mn, produced cell viability reduction and DNA damage (R(2)=0.73). Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  17. Expansion of the Milan criteria without any sacrifice: combination of the Hangzhou criteria with the pre-transplant platelet-to-lymphocyte ratio.

    Science.gov (United States)

    Xia, Weiliang; Ke, Qinghong; Guo, Hua; Wang, Weilin; Zhang, Min; Shen, Yan; Wu, Jian; Xu, Xiao; Yan, Sheng; Yu, Jun; Zhang, Mangli; Zheng, Shusen

    2017-01-05

    The Hangzhou criteria expand the Milan criteria safely and effectively in selecting hepatocellular carcinoma (HCC) candidates for liver transplantation (LT), but some patients exceeding the Milan but fulfilling the Hangzhou criteria still show poor outcomes due to early tumor recurrence. In this study, the platelet-to-lymphocyte ratio (PLR) was employed to differentiate high-risk tumor recurrence recipients, and a new method combining PLR and the Hangzhou criteria was established. The clinical data of 343 LT for HCC were retrospectively analyzed. Receiver operating characteristic (ROC) analysis was used to determine the PLR cut-off value to stratify patients exceeding the Milan but fulfilling the Hangzhou criteria. The recurrence-free survival (RFS) of recipients was compared after stratification. The Hangzhou criteria & PLR method was proposed and its feasibility was validated by ROC analysis. PLR 120 was the most significant cut-off value when comparing RFS of patients exceeding the Milan but fulfilling the Hangzhou criteria. After stratification, the 1-, 3-, and 5-year RFS of patients exceeding the Milan but fulfilling the Hangzhou criteria with PLR sacrifice.

  18. The fate of the postmodern world: On melancholy and rebellion by Milan Mihajlović

    Directory of Open Access Journals (Sweden)

    Vuksanović Ivana

    2016-01-01

    Full Text Available The musical oeuvre of Milan Mihajlović (b. 1945 enjoys a high reputation and position in contemporary Serbian music. This has been proven by the many awards he has received, countless performances of his compositions at home and abroad, and especially by the warm and approving reactions of the audience. The stylistic consistency in his oeuvre is a result of his creative use of Scriabin’s scale. The concept of this scale was first theoretically elaborated in an extensive study written by Mihajlović in 1980 and, since then the scale has been functioning as a crucial cohesive element in all Mihajlović’s compositions. The novelty in his oeuvre, composed during the 1990s, were intertextual references made by using citations from his own works and those of other composers (Monteverdi, Mozart, Stravinsky, Rachmaninov, Vasilije Mokranjac. The most characteristic features of his mature style are also recognizable in his recent works Melancholy (2014 and Rebellion (2015. The interval structure of Skriabin’s scale is projected along the horizontal (melodical and vertical (harmonical axes of the both works while the formal design resulted from shifts of tensions and relaxations. Developmental sections are based on variation and improvisation of the small number of different motifs (three basic ones in Melancholy, four in Rebellion above the metrically moveable ostinato layers and the releases are marked by change of tempo, dynamic, meter and texture. The most significant and radical release is the one which marks the abrupt ending of Rebellion by the physical gesture of slamming down the keyboard lid. As the composition was written for the BUNT festival (Belgrade it fits the festival’s idea of expressing resistance to the government’s neglect of academic musicians and institutions. In the wider sense, it becomes a sign of the resistance to the world we live in, and that is the world of lost ideals. Both works are composed for the wind

  19. Asbestos Lung Burden in Necroscopic Samples from the General Population of Milan, Italy.

    Science.gov (United States)

    Casali, Michelangelo; Carugno, Michele; Cattaneo, Andrea; Consonni, Dario; Mensi, Carolina; Genovese, Umberto; Cavallo, Domenico Maria; Somigliana, Anna; Pesatori, Angela Cecilia

    2015-08-01

    The present study analysed the asbestos lung burden in necroscopic samples from 55 subjects free from asbestos-related diseases, collected between 2009 and 2011 in Milan, Italy. Multiple lung samples were analysed by light microscopy (asbestos bodies, AB) and EDXA-scanning electron microscopy (asbestos fibres and other inorganic fibres). Asbestos fibres were detected in 35 (63.6%) subjects, with a higher frequency for amphiboles than for chrysotile. Commercial (CA) and non-commercial amphiboles (NCA) were found in roughly similar frequencies. The estimated median value was 0.11 million fibres per gram of dry lung tissue (mf g(-1)) for all asbestos, 0.09 mf g(-1) for amphiboles. In 44 (80.0%) subjects no chrysotile fibres were detected. A negative relationship between asbestos mass-weighted fibre count and year of birth (and a corresponding positive increase with age) was observed for amphiboles [-4.15%, 95% confidence interval (CI) = -5.89 to -2.37], talc (-2.12%, 95% CI = -3.94 to -0.28), and Ti-rich fibres (-3.10%, 95% CI = -5.54 to -0.60), but not for chrysotile (-2.84%, 95% CI = -7.69 to 2.27). Residential district, birthplace, and smoking habit did not affect the lung burden of asbestos or inorganic fibres. Females showed higher burden only for amphiboles (0.12 versus 0.03 mf g(-1) in males, P = 0.07) and talc fibres (0.14 versus 0 mf g(-1) in males, P = 0.03). Chrysotile fibres were shorter and thinner than amphibole fibres and NCA fibres were thicker than CA ones. The AB prevalence was 16.4% (nine subjects) with concentrations ranging from 10 to 110 AB g(-1) dry, well below the 1000 AB g(-1) threshold for establishing occupational exposure. No AB were found in subjects younger than 30 years. Our study demonstrated detectable levels of asbestos fibres in a sample taken from the general population. The significant increase with age confirmed that amphibole fibres are the most representative of cumulative exposure. © The Author 2015. Published by Oxford

  20. Electrotherapy in the treatment of patients affected by rabies: experiments conducted at the "Maggiore" hospital of Milan in 1865.

    Science.gov (United States)

    Marinozzi, Silvia; Gulino, Matteo; Gazzaniga, Valentina

    2016-12-01

    During the nineteenth century, the scientific context of rabies treatment was weak due to the lack of the literature on specific nosology of the rabies disease, and unspecific and ineffective therapy approaches. Electrotherapy already represented an important therapeutic approach for nervous system diseases, although not specifically for rabies. In the present paper, the authors discuss the use of electrotherapy in the treatment of humans affected by rabies in an experimental study conducted at the Maggiore Hospital of Milan, with the aim of establishing the discovery of a possible specific therapy. By analyzing the printed scientific sources available in the Braidense Library of Milan, the authors describe four experiments conducted on patients of different ages. Symptoms and effects both during and after the electrotherapy are also highlighted. The experiments demonstrated that electricity is not an effective therapy in the treatment of rabies, being rather able to cause serious functional and organic alterations in all the patients. Analyzing the Milanese experiments, the authors reported specific Italian history of a scientific and medical approach to rabies at the end of the 18th century, which led to the promotion of health education, reinforced prevention strategies and opened the way to the vaccination era.

  1. Masarykʼs Correspondence with the South Slavs: A Collection of Letters from Milan Pribićević to T. G. Masaryk

    Czech Academy of Sciences Publication Activity Database

    Hladký, Ladislav; Škerlová, Jana; Cibulka, Pavel

    2016-01-01

    Roč. 102, č. 3 (2016), s. 393-422 ISSN 0037-6922 Institutional support: RVO:67985963 Keywords : T. G. Masaryk * South Slavs * correspondence * Milan Pribićević * Czech-South Slavs relations Subject RIV: AB - History

  2. Mechanical thermal and electric measurements on materials and components of the main coils of the Milan superconducting cyclotron

    International Nuclear Information System (INIS)

    Acerbi, E.; Rossi, L.

    1988-01-01

    The coils of the Milan Superconducting Cyclotron are the largest superconducting devices built up to now in Italy and constitute the first superconducting magnet for accelerator in Europe. Because of the large stored energy (more than 40 MJ), of the high stresses and of of the need of reliability, a lot of measurements were carried out as well on materials used for the coils, both on superconducting cable and structural materials, as on the main components of the coils and on two double pancakes prototypes (wound with full copper cable). In this paper the results on these measurements are reported and the results of tests on the prototypes are discussed. The aim is to provide an easy source of data for superconducting coils useful to verify calculations or to improve the performances

  3. A multi-source dataset of urban life in the city of Milan and the Province of Trentino.

    Science.gov (United States)

    Barlacchi, Gianni; De Nadai, Marco; Larcher, Roberto; Casella, Antonio; Chitic, Cristiana; Torrisi, Giovanni; Antonelli, Fabrizio; Vespignani, Alessandro; Pentland, Alex; Lepri, Bruno

    2015-01-01

    The study of socio-technical systems has been revolutionized by the unprecedented amount of digital records that are constantly being produced by human activities such as accessing Internet services, using mobile devices, and consuming energy and knowledge. In this paper, we describe the richest open multi-source dataset ever released on two geographical areas. The dataset is composed of telecommunications, weather, news, social networks and electricity data from the city of Milan and the Province of Trentino. The unique multi-source composition of the dataset makes it an ideal testbed for methodologies and approaches aimed at tackling a wide range of problems including energy consumption, mobility planning, tourist and migrant flows, urban structures and interactions, event detection, urban well-being and many others.

  4. The golden altar of S. Ambrogio in Milan: non destructive x-ray fluorescence analysis with a portable apparatus

    International Nuclear Information System (INIS)

    Cesareo, R.; Marabelli, M.; Bandera, S.; Fiorini, C.; Gatti, E.; Leutenegger, P.; Longoni, A.; Gigante, G.E.

    1999-01-01

    The golden altar of S. Ambrogio in Milan is considered one of the most important goldsmith's work never realized. It was constructed in the period between 824 and 859 A.C. approximately. From the metallurgical point of view, ancient gold is composed, besides gold, of silver, copper, iron (< 1%), lead (< 1%) and in some cases of platinum, at trace level. Ancient silver is usually composed by copper, lead, gold (<1%) and iron (< 1%) and in some cases tin, nickel and zinc (at level of traces). The golden altar of S. Ambrogio in Milan was analyzed by means of a portable apparatus using an EDXRF-spectrometer composed by: a) the measuring head composed of a small low-power X-ray tube with a W-anode and working at 30 kV and 0.1 mA, and a thermometrically cooled small size Si-PIN X-ray detector; b) two small boxes for the bias of X-ray tube and detector respectively; c) a multi channel analyzer. For an EDXRF-analysis the measuring head simply touches the surface to be analyzed (approximately 1 cm2 ). The altar of Volvinius was analyzed in about 200 areas; some of them were analyzed twice and at different times, in order to verify the reliability of the apparatus. The four panels of the altar were then analyzed in more than 150 points, in two different sets of measurements. Standard samples were first analyzed, in order to verify the correlation between counts and concentration. Values obtained from the measurements are well comparable with standard values, within the experimental errors. This work was partially supported by the Progetto finalizzato Beni Culturali of the Consiglio Nazionale delle Ricerche

  5. Something going on in Milan: a review of the 4th International PhD Student Cancer Conference.

    Science.gov (United States)

    Segré, C

    2010-01-01

    The 4th International PhD Student Cancer Conference was held at the IFOM-IEO-Campus in Milan from 19-21 May 2010 http://www.semm.it/events_researchPast.phpThe Conference covered many topics related to cancer, from basic biology to clinical aspects of the disease. All attendees presented their research, by either giving a talk or presenting a poster. This conference is an opportunity to introduce PhD students to top cancer research institutes across Europe.THE CORE PARTICIPANTING INSTITUTES INCLUDED: European School of Molecular Medicine (SEMM)-IFOM-IEO Campus, MilanBeatson Institute for Cancer Research (BICR), GlasgowCambridge Research Institute (CRI), Cambridge, UKMRC Gray Institute of Radiation Biology (GIROB), OxfordLondon Research Institute (LRI), LondonPaterson Institute for Cancer Research (PICR), ManchesterThe Netherlands Cancer Institute (NKI), Amsterdam'You organizers have crushed all my prejudices towards Italians. Congratulations, I enjoyed the conference immensely!' Even if it might have sounded like rudeness for sure this was supposed to be a genuine compliment (at least, that's how we took it), also considering that it was told by a guy who himself was the fusion of two usually antithetical concepts: fashion style and English nationality.The year 2010 has marked an important event for Italian research in the international scientific panorama: the European School of Molecular Medicine (SEMM) had the honour to host the 4th International PhD Student Cancer Conference, which was held from 19-21 May 2010 at the IFOM-IEO-Campus (http://www.semm.it/events_researchPast.php) in Milan.The conference was attended by more than one hundred students, coming from a selection of cutting edge European institutes devoted to cancer research. The rationale behind it is the promotion of cooperation among young scientists across Europe to debate about science and to exchange ideas and experiences. But that is not all, it is also designed for PhD students to get in touch

  6. 1-hour time resolution data of PM2.5 composition and gaseous precursors in background Milan: pollution sources and atmospheric processes, and their implications for air quality.

    Science.gov (United States)

    Bigi, Alessandro; Bianchi, Federico; De Gennaro, Gianluigi; Di Gilio, Alessia; Fermo, Paola; Ghermandi, Grazia; Prévôt, André; Urbani, Monia; Valli, Gianluigi; Vecchi, Roberta; Piazzalunga, Andrea

    2017-04-01

    Aim of this study is the investigation of processes leading to atmospheric pollutants formation and ageing in Milan, Po valley, i.e. one of the main hotspot region in Europe. Few 1-hour time resolution campaigns were accomplished in Milan urban area and none of these dealt with simultaneous characterization of atmospheric pollutants in both gas and particle phase. The present study is based on a thorough analysis of hourly data of atmospheric pollutants and of main PM2.5 compounds, and it includes several soluble inorganic aerosols (Cl-, NO2-, NO3-, SO42-, K+, Mg2+, Ca2+, Na+, NH4+), gases (HCl, HNO2, HNO3, NH3, NO, NO2, O3, SO2) organic, elemental and black carbon and meteorological parameters. The data proceed from an intensive sampling campaign in urban background Milan in summer 2012 (Bigi et al., 2017). Data analysis methods used include mean diurnal pattern on weekdays and Sundays, pollution roses, bivariate polar plots and statistical models using backtrajectories. Results show how nitrous acid (HONO) was mainly formed heterogeneously at nighttime, with a dependence of its formation rate on NO2 consistent with observations during the last HONO campaign in Milan in summer 1998, although since 1998 a drop in HONO levels occurred following to the decrease of its precursors. Nitrate showed two main formation mechanisms: one occurring through N2O5 at nighttime and leading to nitrate formation onto existing particles; another occurring both daytime and nighttime following the homogeneous reaction of ammonia gas with nitric acid gas. Air masses reaching Milan influenced nitrate formation depending on their content in ammonia and the timing of arrival. Notwithstanding the low level of SO2 in Milan, its peaks were associated to point source emissions in the Po valley or shipping and power plant emissions SW of Milan, beyond the Apennines. A distinctive pattern for HCl was observed, featured by an afternoon peak and a morning minimum, and best correlated to

  7. Release of IL-1β Triggered by Milan Summer PM10: Molecular Pathways Involved in the Cytokine Release

    Science.gov (United States)

    Bengalli, Rossella; Molteni, Elisabetta; Longhin, Eleonora; Refsnes, Magne; Camatini, Marina; Gualtieri, Maurizio

    2013-01-01

    Particulate matter (PM) exposure is related to pulmonary and cardiovascular diseases, with increased inflammatory status. The release of the proinflammatory interleukin- (IL-) 1β, is controlled by a dual pathway, the formation of inactive pro-IL-1β, through Toll-like receptors (TLRs) activation, and its cleavage by NLRP3 inflammasome. THP-1-derived macrophages were exposed for 6 h to 2.5 μg/cm2 of Milan PM10, and the potential to promote IL-1β release by binding TLRs and activating NLRP3 has been examined. Summer PM10, induced a marked IL-1β response in the absence of LPS priming (50-fold increase compared to unexposed cells), which was reduced by caspase-1 inhibition (91% of inhibition respect summer PM10-treated cells) and by TLR-2 and TLR-4 inhibitors (66% and 53% of inhibition, resp.). Furthermore, summer PM10 increased the number of early endosomes, and oxidative stress inhibition nearly abolished PM10-induced IL-1β response (90% of inhibition). These findings suggest that summer PM10 contains constituents both related to the activation of membrane TLRs and activation of the inflammasome NLPR3 and that TLRs activation is of pivotal importance for the magnitude of the response. ROS formation seems important for PM10-induced IL-1β response, but further investigations are needed to elucidate the molecular pathway by which this effect is mediated. PMID:23509682

  8. Release of IL-1β Triggered by Milan Summer PM10: Molecular Pathways Involved in the Cytokine Release

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    Rossella Bengalli

    2013-01-01

    Full Text Available Particulate matter (PM exposure is related to pulmonary and cardiovascular diseases, with increased inflammatory status. The release of the proinflammatory interleukin- (IL- 1β, is controlled by a dual pathway, the formation of inactive pro-IL-1β, through Toll-like receptors (TLRs activation, and its cleavage by NLRP3 inflammasome. THP-1-derived macrophages were exposed for 6 h to 2.5 μg/cm2 of Milan PM10, and the potential to promote IL-1β release by binding TLRs and activating NLRP3 has been examined. Summer PM10, induced a marked IL-1β response in the absence of LPS priming (50-fold increase compared to unexposed cells, which was reduced by caspase-1 inhibition (91% of inhibition respect summer PM10-treated cells and by TLR-2 and TLR-4 inhibitors (66% and 53% of inhibition, resp.. Furthermore, summer PM10 increased the number of early endosomes, and oxidative stress inhibition nearly abolished PM10-induced IL-1β response (90% of inhibition. These findings suggest that summer PM10 contains constituents both related to the activation of membrane TLRs and activation of the inflammasome NLPR3 and that TLRs activation is of pivotal importance for the magnitude of the response. ROS formation seems important for PM10-induced IL-1β response, but further investigations are needed to elucidate the molecular pathway by which this effect is mediated.

  9. Knowledge of human papillomavirus infection and its prevention among adolescents and parents in the greater Milan area, Northern Italy

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    Consolo Silvia

    2010-06-01

    Full Text Available Abstract Background In order to be widely accepted by users, the implementation of a new health intervention requires them to be adequately informed about its clinical importance, benefits and risks. The aim of this study was to provide data on the knowledge of Italian adolescents and parents concerning human papillomavirus (HPV infection and its prevention in order to allow the development of adequate training programmes. Methods Between 2 May and 15 June 2008, we made a cross-sectional survey of 863 high school students and 2,331 parents of middle and high school students using two anonymously completed questionnaires covering the knowledge of HPV infection and related diseases, and attitudes to vaccinations. The approached schools were a convenience sample of the schools of the greater Milan area, Northern Italy. Results More mothers than fathers were aware that HPV infection could concern their children (58% vs 53%; p = 0.004 and were favourable towards vaccinating their children against HPV (68% vs 65%; p = 0.03; among the students, more females than males were aware that HPV infection could concern themselves (45% vs 26%; p vs 40%; p Conclusions Both students and parents seem to underestimate the likelihood of HPV infection, and this is associated with a lower propensity for vaccination. This is an important indication for future training programmes concerning HPV prevention designed to increase the acceptance of HPV vaccine in families.

  10. Investigating distribution patterns of airborne magnetic grains trapped in tree barks in Milan, Italy: insights for pollution mitigation strategies

    Science.gov (United States)

    Vezzola, Laura C.; Muttoni, Giovanni; Merlini, Marco; Rotiroti, Nicola; Pagliardini, Luca; Hirt, Ann M.; Pelfini, Manuela

    2017-08-01

    High levels of air particulate matter (PM) have been positively correlated with respiratory diseases. In this study, we performed a biomonitoring investigation using samples of bark obtained from trees in a selected study area in the city of Milan (northern Italy). Here, we analyse the magnetic and mineralogical properties of the outer and inner barks of 147 trees, finding that magnetite is the prevalent magnetic mineral. The relative concentration of magnetite is estimated in the samples using saturation isothermal remanent magnetization (SIRM) and hysteresis parameters. We also make a first-order estimate of absolute magnetite concentration from the SIRM. The spatial distribution of the measured magnetic parameters is evaluated as a function of the distance to the main sources of magnetic PM in the study area, for example, roads and tram stops. These results are compared with data from a substantially pollution-free control site in the Central Italian Alps. Magnetic susceptibility, SIRM and magnetite concentration are found to be the highest in the outer tree barks for samples that are closest to roads and especially tram stops. In contrast, the inner bark samples are weakly magnetic and are not correlated to the distance from magnetite PM sources. The results illustrate that trees play an important role acting as a sink for airborne PM in urban areas.

  11. [Mobbing and its effects on health. the experience of the "Clinica del Lavoro Luigi Devoto" in Milan].

    Science.gov (United States)

    Punzi, Silvia; Cassitto, Maria Grazia; Castellini, Giovanna; Costa, G; Gilioli, R

    2007-01-01

    There is increasing interest in research, prevention and management of mobbing in the field of occupational psychosocial risks. To describe mobbing and its health effects by analysis of the cases examined from 1997 to 2003 at the Department of Occupational Health "Clinica del Lavoro Luigi Devoto" in Milan. A total of 226 clinical records of patients who reported a mobbing situation when undergoing medical examination were selected out of 2455 patients examined for stress-related disorders. The percentage of women was higher (53.1%) than in men (46.9%) with a prevalent age range of 35-54 years. There was a great variety of jobs, especially white-collars and workers in large service companies. In one third of the cases, mobbing occurred within 4 years from beginning of employment and mostly after company reorganization and management changes. The most frequent negative acts included social isolation and demotion. The most frequent symptoms were exhaustion, sleep, mood and sexual disorders. The number of symptoms was not related to the duration of mobbing but to the number and frequency of negative actions. 61.1% of the subjects took psychotropic drugs. Occupational health physicians play an essential role in primary prevention (information on occupational risks) and in early diagnosis and rehabilitation and could act as mediators between workers and enterprises.

  12. New strategies to ensure good patient–physician communication when treating adolescents and young adults with cancer: the proposed model of the Milan Youth Project

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    Magni MC

    2015-08-01

    Full Text Available Maria Chiara Magni,1 Laura Veneroni,1 Carlo Alfredo Clerici,2 Tullio Proserpio,3 Giovanna Sironi,1 Michela Casanova,1 Stefano Chiaravalli,1 Maura Massimino,1 Andrea Ferrari1 1Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; 2Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 3Pastoral Care Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy Abstract: Adolescence is a particularly complex time of life, entailing physiological, psychological, and social changes that further the individual's cognitive, emotional, and social growth. Being diagnosed with cancer at this time can have important consequences on an individual's emotional and physical development, and adolescent and young adult cancer patients have particular medical and psychosocial needs. Patient–physician communications are important in any clinical relationship, but fundamental in the oncological sphere because their quality can affect the patient–physician relationship, the therapeutic alliance, and patient compliance. A major challenge when dealing with adolescent and young adult patients lies in striking the right balance between their need and right to understand their disease, treatment, and prognosis, and the need for them to remain hopeful and to protect their emotional sensitivity. We herein describe the activities of the Youth Project of the Istituto Nazionale Tumori in Milan, Italy in order to share a possible model of interaction with these special patients and the tactics our group has identified to help them communicate and share their thoughts. This model implies not only the involvement of a multidisciplinary team, including psychologists and spirituality experts, but also the constitution of dedicated creative activities to give patients the opportunity to express feelings they would otherwise never feel at ease putting into words. These efforts seek the goal to minimize the potentially

  13. [Manual handling of loads in the hotel trade: the experience of the ASL (Local Health Unit) Milan].

    Science.gov (United States)

    Fontani, S; Mercuri, Irene; Salicco, R; Veratti, Silvia; Sorrentino, L

    2010-01-01

    There are over 400 hotels in Milan with a guest capacity of about 62,000 and employing more than 10,000 workers. In 2008/09 the Occupational Health and Safety Service of A.S.L. Milano (Local Health Unit) carried out research into the hotel trade to ascertain the development of this commercial sector, also in view of EXPO 2015. The aim of the project was to improve hygiene and safety conditions and carry out preventive measures. A specific purpose was to study manual handling of loads and repetitive movements risk. The study covered 30 hotels and 7 temporary staff cooperatives. We acquired the Risk Evaluation Document, the Health Surveillance Programme and Registers of Labour Accidents to analyze manual handling of loads and repetitive movements. In the investigations and assessments on hotels we used currently available scientific tools--NIOSH Lifting Index, Push and Pulling Analysis, OC.R.A. Check-List--to study risks related to handling loads and upper limb mechanical overload, which revealed a specific occupational risk that requires a fresh approach to prevention and safety in the entire sector. Chambermaid: LI (Range): 0.57-2.75; Push and Pulling Actions: Fi 0.66-Fm 1.5 and Fi 0.76-Fm 1.33 respectively; OC.R.A. Check-List: 21. Porter: LI (Range): 0.77-3.75. Maintenance staff LI (Range): 0.57-2.75. The study highlighted the presence of risk due to manual handling of loads and repetitive movements in porters, maintenance personnel and particularly in chambermaids that up to now have been poorly assessed by safety experts. Analysis of the information contained in the registers of labour accidents suggests that a significant number of accidents can be related to muscular-skeletal disorders that affect especially cleaning, portering and kitchen staff

  14. Arts and science under the sign of Leonardo. The case of the National Museum of Science and Technology ‘Leonardo da Vinci’ of Milan (Italian original version

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    Claudio Giorgione

    2009-06-01

    Full Text Available Drawing on the example of Leonardo da Vinci, who was able to combine arts and science in his work, the National Museum of Science and Technology of Milan has always pursued the blending and the dialogue of humanistic and scientific knowledge. It has employed this approach in all of its activities, from the set design of exhibition departments to the acquisition of collections and, more recently, in the dialogue with the public. Now more than ever, following a renewal path for the Museum, these guidelines are being subject to research to achieve a new and more up-to-date interpretation.

  15. Arts and science under the sign of Leonardo. The case of the National Museum of Science and Technology ‘Leonardo da Vinci’ of Milan

    Directory of Open Access Journals (Sweden)

    Claudio Giorgione

    2009-06-01

    Full Text Available Drawing on the example of Leonardo da Vinci, who was able to combine arts and science in his work, the National Museum of Science and Technology of Milan has always pursued the blending and the dialogue of humanistic and scientific knowledge. It has employed this approach in all of its activities, from the set design of exhibition departments to the acquisition of collections and, more recently, in the dialogue with the public. Now more than ever, following a renewal path for the Museum, these guidelines are being subject to research to achieve a new and more up-to-date interpretation.

  16. Applying Bim to Built Heritage with Complex Shapes: the Ice House of Filarete's Ospedale Maggiore in Milan, Italy

    Science.gov (United States)

    Oreni, D.; Karimi, G.; Barazzetti, L.

    2017-08-01

    This paper presents the development of a BIM model for a stratified historic structure characterized by a complex geometry: Filarete's Ospedale Maggiore ice house, one of the few remaining historic ice houses in Milan (Fig. 1). Filarete, a well-known Renaissance architect and theorist, planned the hospital in the 15th century, but the ice house was built two centuries later with a double-storey irregular octagonal brick structure, half under and half above ground, that enclosed another circular structure called the ice room. The purpose of the double-walled structure was to store ice in the middle and store and preserve perishable food and medicine at the outer side of the ice room. During World War II, major portions of the hospital and the above-ground section of the ice house was bombed and heavily damaged. Later, in 1962, the hospital was restored and rehabilitated into a university, with the plan to conceal the ice house's remaining structure in the courtyard, which ultimately was excavated and incorporated into a new library for the university. A team of engineers, architects, and students from Politecnico di Milano and Carleton University conducted two heritage recording surveys in 2015 and 2016 to fully document the existing condition of the ice house, resulting in an inclusive laser scanner and photogrammetric point cloud dataset. The point cloud data was consolidated and imported into two leading parametric modelling software, Autodesk Revitand Graphisoft ArchiCAD©, with the goal to develop two BIMs in parallel in order to study and compare the software BIM workflow, parametric capabilities, attributes to capture the complex geometry with high accuracy, and the duration for parametric modelling. The comparison study of the two software revealed their workflow limitations, leading to integration of the BIM generative process with other pure modelling software such as Rhinoceros©. The integrative BIM process led to the production of a comprehensive BIM

  17. APPLYING BIM TO BUILT HERITAGE WITH COMPLEX SHAPES: THE ICE HOUSE OF FILARETE’S OSPEDALE MAGGIORE IN MILAN, ITALY

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    D. Oreni

    2017-08-01

    Full Text Available This paper presents the development of a BIM model for a stratified historic structure characterized by a complex geometry: Filarete’s Ospedale Maggiore ice house, one of the few remaining historic ice houses in Milan (Fig. 1. Filarete, a well-known Renaissance architect and theorist, planned the hospital in the 15th century, but the ice house was built two centuries later with a double-storey irregular octagonal brick structure, half under and half above ground, that enclosed another circular structure called the ice room. The purpose of the double-walled structure was to store ice in the middle and store and preserve perishable food and medicine at the outer side of the ice room. During World War II, major portions of the hospital and the above-ground section of the ice house was bombed and heavily damaged. Later, in 1962, the hospital was restored and rehabilitated into a university, with the plan to conceal the ice house’s remaining structure in the courtyard, which ultimately was excavated and incorporated into a new library for the university. A team of engineers, architects, and students from Politecnico di Milano and Carleton University conducted two heritage recording surveys in 2015 and 2016 to fully document the existing condition of the ice house, resulting in an inclusive laser scanner and photogrammetric point cloud dataset. The point cloud data was consolidated and imported into two leading parametric modelling software, Autodesk Revit© and Graphisoft ArchiCAD©, with the goal to develop two BIMs in parallel in order to study and compare the software BIM workflow, parametric capabilities, attributes to capture the complex geometry with high accuracy, and the duration for parametric modelling. The comparison study of the two software revealed their workflow limitations, leading to integration of the BIM generative process with other pure modelling software such as Rhinoceros©. The integrative BIM process led to the production

  18. Impact of nitrous acid photolysis on the total hydroxyl radical budget during the Limitation of Oxidant Production/Pianura Padana Produzione di Ozono study in Milan

    Science.gov (United States)

    Alicke, B.; Platt, U.; Stutz, J.

    2002-11-01

    The photolysis of nitrous acid (HONO) in the early morning hours is believed to be a significant source of hydroxyl radicals (OH), the most important daytime oxidizing species. Although the importance of this mechanism has been recognized for many years, no accurate experimental quantification is available. Here we present measurements of HONO, NO2, SO2, O3 and HCHO by Differential Optical Absorption Spectroscopy (DOAS) during the Limitation of Oxidant Production/Pianura Padana Produzione di Ozono (LOOP/PIPAPO) study in May-June 1998 in Milan, Italy. The concentration of NO and J(NO2)/J(HONO) were simultaneously monitored by in situ monitors. The photolysis frequencies of HCHO and O3 were determined with a radiative transfer model. High nocturnal HONO mixing ratios of up to 4.4 ppb were regularly observed. Elevated daytime HONO levels during cloudy periods show that the formation of HONO proceeds after sunrise and therefore also represents a source of hydroxyl radicals throughout the day. Averaged over 24 hours, HCHO photolysis is the most important source of OH in Milan, followed by either ozone or HONO photolysis. Our observations indicate that on certain days the OH production from HONO can be even more important than that from ozone photolysis. The diurnal variation of the different OH formation mechanisms shows that HONO photolysis is by far the most important source in the early hours of the morning, and can be as large as and even surpass the total OH production at noon.

  19. [The effects of the traffic restriction fee (Ecopass) in the center of Milan on urban pollution with particulate matter: the results of a pilot study].

    Science.gov (United States)

    Ruprecht, Ario A; Invernizzi, Giovanni

    2009-01-01

    the city of Milan introduced a traffic charging zone in city center in January 2008, named Ecopass. to compare PM1, PM2,5 and PM10 levels in and outside the restricted area before and after the enforcement of the charging scheme. PM1, PM2,5 and PM10 exposures were measured by means of pre-calibrated portable laser-operated particle analyzers. PM10 data from the ARPA official monitoring stations were also evaluated. during a walking trip from Piazza Loreto (outside) to Piazza Duomo (inside Ecopass zone) and back, mean (SD) PM1, PM2,5 and PM10 were 31 (6), 68 (24) and 93 (37) microg/m3 inside the Ecopass zone, and 32 (6), 70 (37), 98 (48) microg/m3 in the outer area, respectively (not significant, ns). In another trip walking from Piazza Buonarroti to Piazza Duomo and back, PM1, PM2,5 and PM10 levels were 56 (2), 183 (14) and 245 (28) microg/m3 inside the Ecopass zone, and 58 (3), 197 (13) and 247 (24) microg/m3 in the outer area, respectively (ns). In the measurements taken from a car moving in three ring belts--one inside the restricted zone, and two outer radial orbitals--PM1, PM2,5 and PM10 levels were found 41 (1), 110 (8) and 148 (16) microg/m3 inside the Ecopass area, 42 (3), 116 (14) and 152 (28) microg/m3 along the middle belt, and 39 (4), 102 (15) and 127 (23) microg/m3 along the greater Milan orbital ("Tangenziale"), respectively (ns). Mean (SD) PM10 levels from ARPA in the two months before the enforcement were 71.2 (32.6) and 74.8 (38.4) microg/m3, in the Ecopass zone and outside, respectively while after the enforcement were 67.3 (36.4) and 70.9 (38.3) microg/m3 of PM10, respectively (ns). no signficant improvement in air quality was observed after the enforcement of the Ecopass charging zone in Milan. In spite of their limitations, the present data confirm that small scale reductions in particle emissions are not sufficient to reach the goal of an improvement in air quality. Large scale, coordinated interventions on an inter-regional basis are

  20. Postoperative Albumin-Bilirubin Grade Change Predicts the Prognosis of Patients with Hepatitis B-Related Hepatocellular Carcinoma Within the Milan Criteria.

    Science.gov (United States)

    Li, Chuan; Zhang, Xiao-Yun; Peng, Wei; Wen, Tian-Fu; Yan, Lu-Nan; Li, Bo; Yang, Jia-Yin; Wang, Wen-Tao; Xu, Ming-Qing

    2017-11-14

    Albumin-bilirubin (ALBI) grade has been validated as a simple, evidence-based, and objective prognostic tool for patients with hepatocellular carcinoma (HCC). However, minimal information is available concerning postoperative ALBI grade changes in HCC. This study aimed to investigate the prognostic value of postoperative ALBI grade changes in patients with hepatitis B virus (HBV)-related HCC within the Milan criteria after liver resection. Patients with HBV-related HCC within the Milan criteria who underwent liver resection between 2010 and 2016 at West China Hospital were reviewed (N = 258). A change in ALBI grade was defined as first postoperative month ALBI grade-preoperative ALBI grade. If the value was >0, postoperative worsening of ALBI grade was considered; otherwise, stable ALBI grade was considered. Cox proportional hazard regression analyses were used to determine the factors that influence recurrence and survival. During the follow-up, 130 patients experienced recurrence and 47 patients died. Multivariate analyses revealed that postoperative worsening of ALBI grade (HR 1.541, 95% CI 1.025-2.318, P = 0.038), microvascular invasion (MVI, HR 1.802, 95% CI 1.205-2.695, P = 0.004), and multiple tumors (HR 1.676, 95% CI 1.075-2.615, P = 0.023) were associated with postoperative recurrence, whereas MVI (HR 2.737, 95% CI 1.475-5.080, P = 0.001), postoperative worsening of ALBI grade (HR 2.268, 95% CI 1.227-4.189, P = 0.009), high alpha-fetoprotein level (HR 2.055, 95% CI 1.136-3.716, P = 0.017), and transfusion (HR 2.597, 95% CI 1.395-4.834, P = 0.003) negatively influenced long-term survival. Patients with postoperative worsening of ALBI grade exhibited increased incidence of recurrence and worse long-term survival. Postoperative worsening of ALBI grade was associated with increased recurrence and poorer overall survival for patients with HBV-related HCC within the Milan criteria. We should pay attention to liver function changes in HCC patients

  1. Final Report on an Analysis of the Education and Training Systems at Milan, Michigan and Terre Haute, Indiana to Federal Prison Industries Incorporated, U.S. Department of Justice.

    Science.gov (United States)

    Hitt, William D.; And Others

    Existing education and training (E&T) programs at the Terre Haute Penitentiary, Indiana, and the Milan Federal Correctional Institution, Michigan, were described and evaluated. Needs, objectives, inmate classification and placement, staff, and other aspects were covered. Reports, staff and inmate interviews, study of instructional materials, and…

  2. Il ruolo del paradosso nel gioco e nel comico: una lettu-ra del racconto “Il falso autostop” di Milan Kundera

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    Darwine Delvecchio

    2017-12-01

    Full Text Available In questo articolo vogliamo esporre gli studi che hanno riconosciuto al paradosso un ruolo centrale non soltanto nel discorso comico ma anche nella comunicazione umana più in generale, confrontandoli con la nostra tesi sull’“assurdo comico”. Nella nostra prospettiva l'essenza della comicità è paradossale dal momento che essa rappresenta l'intreccio insolubile fra due domini modali che le logiche disgiuntive e la nostra comune idea della “realtà quotidiana” mantengono nettamente distinti: l'impossibile e l'effettuale. Alla parte teorica, dedicata alle teorie di Gregory Bateson e di William F. Fry, che elaborano in maniera originale l’intreccio fra i concetti di gioco, paradosso e finizione, seguirà l’analisi del racconto “Il falso autosop” di Milan Kundera, che mostra i limiti delle loro teorie e un’opportunità di arricchimento per mezzo del concetto di “assurdo comico”.

  3. The architect Milan Lojanica’s Belgrade realm and visions - from a graduation project to Julino brdo and Gocław, 1962-1972

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    Mokranjac Aleksandra

    2016-01-01

    Full Text Available Attempting to highlight the specificity of the architect Milan Lojanica’s design approach, clearly distinct in his first professional decennary 1962-1972, the focus of this paper is on his firstly designed and developed, and afterwards awarded architectural masterpiece, which he realized with his associates, architects Cagić and Jovanović - i.e. the urban suprastructure of Julino brdo/Jula’s hill (1967-1970. As fifty years has passed from its first drawings, and the project documentation consists of exceptionally rare fragments only, one of the main goals of the research was the attempt to reconstruct the complete creative process - including its particular modality of construction/materialization. Although in its results merely a brief recapitulation of Lojanica’s innovative beginnings, the discourse still may provide a source-material for the genre of textbooks - from student to technical practice - regarding the rarest and almost forgotten discipline of experimental urban (masshousing, with artistic/spiritual/serene touch of a refined prefabricated system. Nonetheless, the opus of the eminent author, the respected creative endeavor of Milan Lojanica, future professor of architecture and the SASA academic, arises from its earliest stages and then permanently confirms itself as an entirety in its continuity. Therefore, the small-scale Julino brdo/Jula’s hill settlement case study is reanalyzed/rethought within Lojanica’s antecedent thematic preoccupations, and additionally within the most challenging subsequent one - the Gocław project (1972, Poland (Polska, throughout its emerging, unrivaled, innovatively envisioned - town/city of hundred-thousand-inhabitants.

  4. Italian horticultural and culinary records of summer squash (Cucurbita pepo, Cucurbitaceae) and emergence of the zucchini in 19th-century Milan.

    Science.gov (United States)

    Lust, Teresa A; Paris, Harry S

    2016-07-01

    Summer squash, the young fruits of Cucurbita pepo, are a common, high-value fruit vegetable. Of the summer squash, the zucchini, C. pepo subsp. pepo Zucchini Group, is by far the most cosmopolitan. The zucchini is easily distinguished from other summer squash by its uniformly cylindrical shape and intense colour. The zucchini is a relatively new cultivar-group of C. pepo, the earliest known evidence for its existence having been a description in a book on horticulture published in Milan in 1901. For this study, Italian-language books on agriculture and cookery dating from the 16th to 19th centuries have been collected and searched in an effort to follow the horticultural development and culinary use of young Cucurbita fruits in Italy. The results indicate that Cucurbita fruits, both young and mature, entered Italian kitchens by the mid-16th century. A half-century later, round and elongate young fruits of C. pepo were addressed as separate cookery items and the latter had largely replaced the centuries-old culinary use of young, elongate bottle gourds, Lagenaria siceraria Allusion to a particular, extant cultivar of the longest fruited C. pepo, the Cocozelle Group, dates to 1811 and derives from the environs of Naples. The Italian diminutive word zucchini arose by the beginning of the 19th century in Tuscany and referred to small, mature, desiccated bottle gourds used as containers to store tobacco. By the 1840s, the Tuscan word zucchini was appropriated to young, primarily elongate fruits of C. pepo The Zucchini Group traces its origins to the environs of Milan, perhaps as early as 1850. The word zucchini and the horticultural product zucchini arose contemporaneously but independently. The results confirm that the Zucchini Group is the youngest of the four cultivar-groups of C. pepo subsp. pepo but it emerged approximately a half-century earlier than previously known. © The Author 2016. Published by Oxford University Press on behalf of the Annals of Botany

  5. On the Relation Between the Designing Process and the Post-Processing of Couture Maison in Milan Influence That Manufacturing Process of Pret-A-Porter Exerts on Product Design

    OpenAIRE

    大谷, 毅; 池田, 和子; 伊崎, 晴子; 正田, 康博; 森川, 英明

    2012-01-01

    The Japanese fashion business has a low international presence. While it had been skillful in the import and licensing businesses, these businesses do not involve schemes for selling fashion goods on the global market through proactive entrepreneurial creativity. For this reason, one of the research themes of this study is to clarify the features of the design and manufacturing processes in a Milan fashion house (couture-maison) built on a high level of creativity. The following findings were...

  6. The Involvement of Albanian Ethnic Immigrants in Entrepreneurship as a New Possibility on their Integration in the International Labour Market - Their Role in Transnational Bridging For Homemade Products (Case Of The Province Of Milan, Italy

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    MA. Ilir Bejta

    2013-12-01

    Economic integration induces immigrants to increase contacts and be part of economic networks and  social networks too, as well as improve, as a necessity deriving from the economic competition, their human capital capacities and capabilities getting use of international labour market. Considering economic and human capital development we will measure their impact on the social welfare and integration of the ethnic immigrant minority groups in the modern society (Albanians in Province of Milan, Italy.

  7. Impact of Highly Reflective Materials on Meteorology, PM10 and Ozone in Urban Areas: A Modeling Study with WRF-CHIMERE at High Resolution over Milan (Italy

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    Serena Falasca

    2018-02-01

    Full Text Available The Urban Heat Island (UHI is a well-known phenomenon concerning an increasing percentage of the world’s population due to the growth rates of metropolitan areas. Given the health and economic implications of UHIs, several mitigation techniques are being evaluated and tested. In this study, we consider the use of highly reflective materials for urban surfaces, and we carried out numerical experiments using the Weather Research and Forecasting model coupled with the CHIMERE model in order to investigate the effects of these materials on the meteorology and air quality in the urban area of Milan (Italy. Results show that an increase in albedo from 0.2 to 0.7 for urban roofs, walls and streets leads to a decrease in UHI intensity by up to 2–3 °C and of the planetary boundary layer (PBL height of about 500 m. However, the difference of PM10 and ozone between urban and surrounding areas increases by a factor of about 2, attributable to the reduction of PBL height and wind speed and to the increased reflected solar radiation that may enhance photochemical production during the daytime. Therefore, if anthropogenic emissions are held at the same levels, the potential benefit to the UHI in terms of thermal discomfort may have negative repercussions on air quality.

  8. a N-D Virtual Notebook about the Basilica of S. Ambrogio in Milan: Information Modeling for the Communication of Historical Phases Subtraction Process

    Science.gov (United States)

    Stanga, C.; Spinelli, C.; Brumana, R.; Oreni, D.; Valente, R.; Banfi, F.

    2017-08-01

    This essay describes the combination of 3D solutions and software techniques with traditional studies and researches in order to achieve an integrated digital documentation between performed surveys, collected data, and historical research. The approach of this study is based on the comparison of survey data with historical research, and interpretations deduced from a data cross-check between the two mentioned sources. The case study is the Basilica of S. Ambrogio in Milan, one of the greatest monuments in the city, a pillar of the Christianity and of the History of Architecture. It is characterized by a complex stratification of phases of restoration and transformation. Rediscovering the great richness of the traditional architectural notebook, which collected surveys and data, this research aims to realize a virtual notebook, based on a 3D model that supports the dissemination of the collected information. It can potentially be understandable and accessible by anyone through the development of a mobile app. The 3D model was used to explore the different historical phases, starting from the recent layers to the oldest ones, through a virtual subtraction process, following the methods of Archaeology of Architecture. Its components can be imported into parametric software and recognized both in their morphological and typological aspects. It is based on the concept of LoD and ReverseLoD in order to fit the accuracy required by each step of the research.

  9. Canine Fecal Contamination in a Metropolitan Area (Milan, North-Western Italy: Prevalence of Intestinal Parasites and Evaluation of Health Risks

    Directory of Open Access Journals (Sweden)

    Sergio Aurelio Zanzani

    2014-01-01

    Full Text Available Intestinal parasites of dogs represent a serious threat to human health due to their zoonotic potential. Thus, metropolitan areas presenting high concentrations of pets and urban fecal contamination on public areas are at sanitary risk. Major aim of this survey was to determine prevalence of zoonotic parasites in dog fecal samples collected from public soil of Milan (north-western Italy. Differences in parasites prevalence distribution were explored by a geographical information system- (GIS- based approach, and risk factors (human density, sizes of green parks, and dog areas were considered. The metropolitan area was divided into 157 rectangular subareas and sampling was performed following a 1-kilometer straight transect. A total of 463 fecal samples were analyzed using centrifugation-flotation technique and ELISA to detect Giardia and Cryptosporidium coproantigens. A widespread fecal contamination of soil was highlighted, being fecal samples found in 86.8% of the subareas considered. The overall prevalence of intestinal parasites was 16.63%. Zoonotic parasites were found, such as Trichuris vulpis (3.67%, Toxocara canis (1.72%, Strongyloides stercoralis (0.86%, Ancylostomatidae (0.43%, and Dipylidium caninum (0.43%. Giardia duodenalis was the most prevalent zoonotic protozoa (11.06%, followed by Cryptosporidium (1.10%. Faeces from subareas characterized by broad green areas showed to be particularly prone to infection.

  10. A N-D VIRTUAL NOTEBOOK ABOUT THE BASILICA OF S. AMBROGIO IN MILAN: INFORMATION MODELING FOR THE COMMUNICATION OF HISTORICAL PHASES SUBTRACTION PROCESS

    Directory of Open Access Journals (Sweden)

    C. Stanga

    2017-08-01

    Full Text Available This essay describes the combination of 3D solutions and software techniques with traditional studies and researches in order to achieve an integrated digital documentation between performed surveys, collected data, and historical research. The approach of this study is based on the comparison of survey data with historical research, and interpretations deduced from a data cross-check between the two mentioned sources. The case study is the Basilica of S. Ambrogio in Milan, one of the greatest monuments in the city, a pillar of the Christianity and of the History of Architecture. It is characterized by a complex stratification of phases of restoration and transformation. Rediscovering the great richness of the traditional architectural notebook, which collected surveys and data, this research aims to realize a virtual notebook, based on a 3D model that supports the dissemination of the collected information. It can potentially be understandable and accessible by anyone through the development of a mobile app. The 3D model was used to explore the different historical phases, starting from the recent layers to the oldest ones, through a virtual subtraction process, following the methods of Archaeology of Architecture. Its components can be imported into parametric software and recognized both in their morphological and typological aspects. It is based on the concept of LoD and ReverseLoD in order to fit the accuracy required by each step of the research.

  11. La mappa acustica dinamica di Milano da un numero limitato di punti di monitoraggio. Primi risultati - Milan dynamic noise mapping from few monitoring stations. First results

    Directory of Open Access Journals (Sweden)

    Giovanni Zambon

    2016-10-01

    Full Text Available Il questa memoria sono riportati i primi risultati del progetto Dynamap relativi all’area pilota di Milano. Il progetto sviluppa un approccio alla rappresentazione del rumore derivante da traffico stradale che consenta una mappatura acustica dinamica attraverso la scalatura di mappe precalcolate mediante un collegamento diretto con un numero limitato di stazioni di monitoraggio. La possibilità di controllare la mappa acustica di una rete stradale estesa mediante pochi punti di controllo si attua mediante una necessaria aggregazione degli archi stradali in gruppi omogenei. ------ This memory reports the first results of Dynamap project related to the Milan pilot area. The project develops an approach to represent road traffic noise with the outcome of a dynamic noise mapping achieved through the scaling of precalculated maps; scaling is based upon a direct connection to a limited number of noise monitoring stations. The possibility of controlling the acoustic map of an extended road network by means of a few monitoring sites is implemented through a preliminary aggregation of road stretches into homogeneous groups.

  12. Influenza A/H1N1/2009 virus - experience of the clinical microbiology laboratory of the “L. Sacco” University Hospital in Milan

    Directory of Open Access Journals (Sweden)

    Lisa Lucia Chenal

    2011-06-01

    Full Text Available In the spring of 2009, a new variant of influenza A/H1N1 virus that had never been isolated before, was identified. From April 27 to December 31, 2009 the respiratory samples of 974 patients, obtained from suspected cases of pandemic influenza A virus infection, were analyzed at the Clinical Microbiology Laboratory of the “L. Sacco” University Hospital in Milan. The diagnosis of influenza A/H1N1 infection was performed initially through the use of different molecular biological methods: Seeplex® RV12 ACE Detection (Seegene, NUCLISENS® EASYQ® INFLUENZA A/B (bioMérieux, Influenza A/B Q-PCR Alert (Nanogen running in parallel with rRT-PCR (CDC to confirm the positivity to the new influenza virus, then was used a single specific test, Fast set H1N1v (Arrow Diagnostics. Retrospective study of data showed that 293 (30.1% patients were positive for the new strain of influenza A/H1N1 virus and 8 (0.8% for influenza A other than H1N1 virus.The distribution of influenza A/H1N1 cases showed two peaks, one on July (62.9% and the other one on October (36%, moreover we observed that 155 patients (53% out of 293 positive for influenza A/H1N1 virus aged under 20 years old. The first positivity peak was found in travelers and the second one, occurred 2-3 months prior to the classic seasonal epidemic influenza, was attributed to autochthonous cases , by which the virus had spread worldwide. The highest proportion of cases were among subjects aged from 0 to 20 years and, over this age the positivity rate decreased proportionally with increasing age, in agreement with data reported in other countries.

  13. The oncologic outcome and immediate surgical complications of lipofilling in breast cancer patients: a multicenter study--Milan-Paris-Lyon experience of 646 lipofilling procedures.

    Science.gov (United States)

    Petit, Jean Yves; Lohsiriwat, Visnu; Clough, Krishna B; Sarfati, Isabelle; Ihrai, Tarik; Rietjens, Mario; Veronesi, Paolo; Rossetto, Fabio; Scevola, Anna; Delay, Emmanuel

    2011-08-01

    Lipofilling is now performed to improve the breast contour, after both breast-conserving surgery and breast reconstruction. However, injection of fat into a previous tumor site may create a new environment for cancer and adjacent cells. There is also no international agreement regarding lipofilling after breast cancer treatment. The authors included three institutions specializing in both breast cancer treatment and breast reconstruction (European Institute of Oncology, Milan, Italy; Paris Breast Center, Paris, France; and Leon Berard Centre, Lyon, France) for a multicenter study. A collective chart review of all lipofilling procedures after breast cancer treatment was performed. From 2000 to 2010, the authors reviewed 646 lipofilling procedures from 513 patients. There were 370 mastectomy patients and 143 breast-conserving surgery patients. There were 405 patients (78.9 percent) with invasive carcinoma and 108 (21.1 percent) with carcinoma in situ. The average interval between oncologic surgical interventions and lipofilling was 39.7 months. Average follow-up after lipofilling was 19.2 months. The authors observed a complication rate of 2.8 percent (liponecrosis, 2.0 percent). Twelve radiologic images appeared after lipofilling in 119 breast-conserving surgery cases (10.1 percent). The overall oncologic event rate was 5.6 percent (3.6 percent per year). The locoregional event rate was 2.4 percent (1.5 percent per year). Lipofilling after breast cancer treatment leads to a low complication rate and does not affect radiologic follow-up after breast-conserving surgery. A prospective clinical registry including high-volume multicenter data with a long follow-up is warranted to demonstrate the oncologic safety. Until then, lipofilling should be performed in experienced hands, and a cautious oncologic follow-up protocol is advised. Therapeutic, IV [corrected].

  14. Effects of various meteorological conditions and spatial emission resolutions on the ozone concentration & ROG/NOx limitation in the Milan area (I)

    Science.gov (United States)

    Bärtsch-Ritter, N.; Keller, J.; Dommen, J.; Prévát, A. S. H.

    2003-02-01

    The three-dimensional photochemical model UAM-V is used to investigate the effects of various meteorological conditions and of the coarseness of emission inventories on the ozone concentration and ROG/NOx limitation of the ozone production in the Po Basin in the northern part of Italy. As a base case, the high ozone episode with up to 200 ppb on 13 May 1998 was modelled and previously thoroughly evaluated with measurements gained during a large field experiment. The performed variations in meteorology are applied to mixing height, air temperature, specific humidity and wind speed. Three coarser emission inventories are obtained by resampling from 3×3 km2 up to 54×54 km2 emission grids. The model results show that changes in meteorological input files have the largest effect on peak ozone. In the modelled ozone plume a slope of 10.1 ppb ozone/°C and in Milan of 2.8 ppb ozone/°C were found. The net ozone formation in northern Italy is more strongly temperature than humidity dependent, while the humidity is very important for the ROG/NOx limitation of the ozone production. For each of the meteorological variations (e.g. doubling the mixing height), the modelled ozone plume remains ROG limited for this case. A strong change towards NOx sensitivity in the ROG limited areas is only found if much coarser emission inventories were applied. Increasing ROG limited areas with increasing wind speed are found, because the ROG limited ozone chemistry induced by point sources is spread over a larger area. Simulations without point sources tend to increase the NOx limited areas.

  15. Effects of various meteorological conditions and spatial emissionresolutions on the ozone concentration and ROG/NOx limitationin the Milan area (I)

    Science.gov (United States)

    Baertsch-, N., , Ritter; Keller, J.; Dommen, J.; Prevot, A. S. H.

    2004-03-01

    The three-dimensional photochemical model UAM-V is used to investigate the effects of various meteorological conditions and of the coarseness of emission inventories on the ozone concentration and ROG/NOx limitation of the ozone production in the Po Basin in the northern part of Italy. As a base case, the high ozone episode with up to 200ppb on 13 May 1998 was modelled and previously thoroughly evaluated with measurements gained during a large field experiment. Systematic variations in meteorology are applied to mixing height, air temperature, specific humidity and wind speed. Three coarser emission inventories are obtained by resampling from 3x3km2 up to 54x54km2 emission grids. The model results show that changes in meteorological input files strongly influence ozone in this area. For instance, temperature changes peak ozone by 10.1ppb/°C and the ozone concentrations in Milan by 2.8ppb/°C. The net ozone formation in northern Italy is more strongly temperature than humidity dependent, while the humidity is very important for the ROG/NOx limitation of the ozone production. For all meteorological changes (e.g. doubling the mixing height), the modelled peak ozone remains ROG limited. A strong change towards NOx sensitivity in the ROG limited areas is only found if much coarser emission inventories were applied. Increasing ROG limited areas with increasing wind speed are found, because the ROG limited ozone chemistry induced by point sources is spread over a larger area. Simulations without point sources tend to increase the NOx limited areas.

  16. Effects of various meteorological conditions and spatial emissionresolutions on the ozone concentration and ROG/NOx limitationin the Milan area (I

    Directory of Open Access Journals (Sweden)

    N. Baertsch-Ritter

    2004-01-01

    Full Text Available The three-dimensional photochemical model UAM-V is used to investigate the effects of various meteorological conditions and of the coarseness of emission inventories on the ozone concentration and ROG/NOx limitation of the ozone production in the Po Basin in the northern part of Italy. As a base case, the high ozone episode with up to 200ppb on 13 May 1998 was modelled and previously thoroughly evaluated with measurements gained during a large field experiment. Systematic variations in meteorology are applied to mixing height, air temperature, specific humidity and wind speed. Three coarser emission inventories are obtained by resampling from 3x3km2 up to 54x54km2 emission grids. The model results show that changes in meteorological input files strongly influence ozone in this area. For instance, temperature changes peak ozone by 10.1ppb/°C and the ozone concentrations in Milan by 2.8ppb/°C. The net ozone formation in northern Italy is more strongly temperature than humidity dependent, while the humidity is very important for the ROG/NOx limitation of the ozone production. For all meteorological changes (e.g. doubling the mixing height, the modelled peak ozone remains ROG limited. A strong change towards NOx sensitivity in the ROG limited areas is only found if much coarser emission inventories were applied. Increasing ROG limited areas with increasing wind speed are found, because the ROG limited ozone chemistry induced by point sources is spread over a larger area. Simulations without point sources tend to increase the NOx limited areas.

  17. Measuring the expected increase in cycling in the city of Milan and evaluating the positive effects on the population's health status: a Community-Based Urban Planning experience.

    Science.gov (United States)

    Rebecchi, A; Boati, L; Oppio, A; Buffoli, M; Capolongo, S

    2016-01-01

    It's scientifically known that inactivity is one of the major risk factors for Non-Communicable Diseases. One of the elements affecting the choice of transport mode, regarding circulation in the city, is the cities' urban morphology, i.e. the infrastructural facilities for the slow mobility service. Cyclability, in fact, can help to increase daily physical activity level, therefore becoming a protective factor for individual health. After a literature review about the state of the art regarding the correlation between built environment, active transport and quantification of the physical activity level, we have developed a specific questionnaire to collect information about current and forecast use of bicycle, in case of improvement and implementation of the cycling network. The questionnaire also investigated social and health aspects concerning the anamnesis of the interviewees (age, gender, health status, sport activity performed, etc) and users' opinions about existing infrastructure and planned interventions, designed to promote cycling mobility. Aim of the research was to quantify the increase of physical activity people would have realized in front of an improvement of the specific infrastructures, and the expected positive effects in terms of health. The collected data (343 interviewed in a district of Milan, named "Zona 7") demonstrate that through the implementation of the cycle network, there would be more cyclists to practice the 150 minutes weekly of physical activity recommended by WHO: time spent in cycling, indeed, would increases by 34.4% compared to the current level of cyclability, as detected by our survey. The investigation confirmed that urban interventions, especially those in small-scale, could play a key role in the promotion of healthy lifestyles, inducing therefore important positive effects on the population health. It was also carried out an application of the WHO "Health Economic Assessment Tool" to evaluate the benefits in terms of

  18. Null-space Monte Carlo particle tracking to assess groundwater PCE (Tetrachloroethene) diffuse pollution in north-eastern Milan functional urban area.

    Science.gov (United States)

    Alberti, Luca; Colombo, Loris; Formentin, Giovanni

    2018-04-15

    The Lombardy Region in Italy is one of the most urbanized and industrialized areas in Europe. The presence of countless sources of groundwater pollution is therefore a matter of environmental concern. The sources of groundwater contamination can be classified into two different categories: 1) Point Sources (PS), which correspond to areas releasing plumes of high concentrations (i.e. hot-spots) and 2) Multiple-Point Sources (MPS) consisting in a series of unidentifiable small sources clustered within large areas, generating an anthropogenic diffuse contamination. The latter category frequently predominates in European Functional Urban Areas (FUA) and cannot be managed through standard remediation techniques, mainly because detecting the many different source areas releasing small contaminant mass in groundwater is unfeasible. A specific legislative action has been recently enacted at Regional level (DGR IX/3510-2012), in order to identify areas prone to anthropogenic diffuse pollution and their level of contamination. With a view to defining a management plan, it is necessary to find where MPS are most likely positioned. This paper describes a methodology devised to identify the areas with the highest likelihood to host potential MPS. A groundwater flow model was implemented for a pilot area located in the Milan FUA and through the PEST code, a Null-Space Monte Carlo method was applied in order to generate a suite of several hundred hydraulic conductivity field realizations, each maintaining the model in a calibrated state and each consistent with the modelers' expert-knowledge. Thereafter, the MODPATH code was applied to generate back-traced advective flowpaths for each of the models built using the conductivity field realizations. Maps were then created displaying the number of backtracked particles that crossed each model cell in each stochastic calibrated model. The result is considered to be representative of the FUAs areas with the highest likelihood to host

  19. Enlightening music: the catalogue and digitisation project of Verdi’s archive at the “Archivio Storico Ricordi” in Milan

    Directory of Open Access Journals (Sweden)

    Mathias Balbi

    2014-05-01

    Full Text Available Our contribution concentrates on the processes of cataloguing and digitising of hand–written letters and business documents belonging to the ''Ricordi Historical Archive'' in Milan, which is at present housed in the Braidense National Library; the archive possesses documents referring to the history of the publishing company covering the two centuries of its activities. Starting from the ledgers compiled by Giovanni Ricordi, which cover a period from 1814 up to the middle of the 19th century to the documents relative to the school of engraving, the archive also houses a large number of editorial catalogues, published by Ricordi and by other publishing houses which it took over, as well as the original contracts stipulated with composers and librettists from Giuseppe Verdi and Giacomo Puccini to Arrigo Boito. The collection of about 15,000 hand–written letters covers the period from the beginning of the 19th century to the end of the 20th century and includes documents sent to Ricordi from writers, singers authors, and composers such as Giuseppe Verdi, Giacomo Puccini and Ottorino Respighi and librettists Luigi Illica, Giuseppe Giacosa and Arrigo Boito. The second part of the correspondence is made up letter–books and business correspondence which were kept intact from 1888 to 1962, except for the period from 1944 to 1953. Since 2006, work has been carried out to catalogue and digitise the Ricordi Archive based on the standards set out by the National Library Service (Servizio Bibliotecario Nazionale – SBN which is head of the Central Institute for the Single Catalogue (ICCU. The structure and use of the archive and the external transmission of its contents are safeguarded and enhanced thanks to the combined work of cataloguing and digitisation of this heritage: the preliminary cataloguing of the documents uses a simplified model of the scheme adopted in the description of the manuscript according to sw Manus, elaborated by ICCU: the

  20. Impact of Pretransplant Bridging Locoregional Therapy for Patients With Hepatocellular Carcinoma Within Milan Criteria Undergoing Liver Transplantation: Analysis of 3601 Patients From the US Multicenter HCC Transplant Consortium.

    Science.gov (United States)

    Agopian, Vatche G; Harlander-Locke, Michael P; Ruiz, Richard M; Klintmalm, Goran B; Senguttuvan, Srinath; Florman, Sander S; Haydel, Brandy; Hoteit, Maarouf; Levine, Matthew H; Lee, David D; Taner, C Burcin; Verna, Elizabeth C; Halazun, Karim J; Abdelmessih, Rita; Tevar, Amit D; Humar, Abhinav; Aucejo, Federico; Chapman, William C; Vachharajani, Neeta; Nguyen, Mindie H; Melcher, Marc L; Nydam, Trevor L; Mobley, Constance; Ghobrial, R Mark; Amundsen, Beth; Markmann, James F; Langnas, Alan N; Carney, Carol A; Berumen, Jennifer; Hemming, Alan W; Sudan, Debra L; Hong, Johnny C; Kim, Joohyun; Zimmerman, Michael A; Rana, Abbas; Kueht, Michael L; Jones, Christopher M; Fishbein, Thomas M; Busuttil, Ronald W

    2017-09-01

    To evaluate the effect of pretransplant bridging locoregional therapy (LRT) on hepatocellular carcinoma (HCC) recurrence and survival after liver transplantation (LT) in patients meeting Milan criteria (MC). Pre-LT LRT mitigates tumor progression and waitlist dropout in HCC patients within MC, but data on its impact on post-LT recurrence and survival remain limited. Recurrence-free survival and post-LT recurrence were compared among 3601 MC patients with and without bridging LRT utilizing competing risk Cox regression in consecutive patients from 20 US centers (2002-2013). Compared with 747 LT recipients not receiving LRT, 2854 receiving LRT had similar 1, 3, and 5-year recurrence-free survival (89%, 77%, 68% vs 85%, 75%, 68%; P = 0.490) and 5-year post-LT recurrence (11.2% vs 10.1%; P = 0.474). Increasing LRT number [3 LRTs: hazard ratio (HR) 2.1, P < 0.001; 4+ LRTs: HR 2.5, P < 0.001), and unfavorable waitlist alphafetoprotein trend significantly predicted post-LT recurrence, whereas LRT modality did not. Treated patients achieving complete pathologic response (cPR) had superior 5-year RFS (72%) and lower post-LT recurrence (HR 0.52, P < 0.001) compared with both untreated patients (69%; P = 0.010; HR 1.0) and treated patients not achieving cPR (67%; P = 0.010; HR 1.31, P = 0.039), who demonstrated increased recurrence compared with untreated patients in multivariate analysis controlling for pretransplant and pathologic factors (HR 1.32, P = 0.044). Bridging LRT in HCC patients within MC does not improve post-LT survival or HCC recurrence in the majority of patients who fail to achieve cPR. The need for increasing LRT treatments and lack of alphafetoprotein response to LRT independently predict post-LT recurrence, serving as a surrogate for underlying tumor biology which can be utilized for prioritization of HCC LT candidates.

  1. Seasonal behavior of PM2.5 deliquescence, crystallization, and hygroscopic growth in the Po Valley (Milan): Implications for remote sensing applications

    Science.gov (United States)

    D'Angelo, Luca; Rovelli, Grazia; Casati, Marco; Sangiorgi, Giorgia; Perrone, Maria Grazia; Bolzacchini, Ezio; Ferrero, Luca

    2016-07-01

    Atmospheric aerosols deliquescence and crystallization relative humidity (DRH and CRH) are rarely measured compared to the worldwide number of hygroscopicity measurements; this feature comes from the lack of an efficient method able to capture the whole complexity of chemical composition of aerosols. Despite this, the knowledge of both DRH and CRH are crucial for a correct parameterization of the aerosol hygroscopic growth used in different applications, among which the remote sensing is very important. In this paper, a newly developed technique (direct current conductance method) was applied in an aerosol chamber to Milan PM2.5 samples, to identify aerosol DRH and CRH both during winter and summer. These results were compared with those independently obtained by gravimetric measurements conducted in the chamber using a microbalance. Microbalance data allowed also the determination of the mass hygroscopic growth factor on the collected PM2.5 samples. Results evidenced first a good agreement between the two methods (RMSE = 2.7% and 2.3% for DRH and CRH, respectively). Collected data evidenced the hysteresis behavior of ambient particles and variability in both DRH and CRH between the two seasons. Summer samples showed higher DRH and CRH (on average 71.4 ± 1.0% RH and 62.6 ± 1.2% RH, respectively) than the winter ones (on average 55.2 ± 0.7% RH and 46.9 ± 0.6% RH). This behavior was related to the higher content of sulfates during the summer season. Conversely, the mass hygroscopic growth factor at 90% RH was higher for winter samples (2.76 ± 0.06) with respect to the summer ones (1.91 ± 0.11). Since hysteresis behavior affects optical properties of aerosols, when RH conditions are within the loop, the hygroscopic growth factor could be assigned in a wrong way. Thus, the growth factor was calculated within the hysteresis loop for both upper and lower branches: results showed that difference in hygroscopic growth factor could reach up the 24%.

  2. Measurement of black carbon concentration as an indicator of air quality benefits of traffic restriction policies within the ecopass zone in Milan, Italy

    Science.gov (United States)

    Invernizzi, Giovanni; Ruprecht, Ario; Mazza, Roberto; De Marco, Cinzia; Močnik, Griša; Sioutas, Costantinos; Westerdahl, Dane

    2011-07-01

    Traffic restrictions are an unpopular tool to mitigate urban air pollution, and a measurable improvement in air quality is needed to demonstrate the effectiveness of this measure. Previous attempts failed to detect measurable reductions of PM mass pollution within the areas subject to traffic restriction. However black carbon, which is emitted primarily by traffic sources, could be a PM metric more suitable than PM mass to demonstrate pollutant reductions. In this study we report the results of a black carbon monitoring campaign carried out in Milan, Italy, with the aim to detect - and demonstrate more suitably than PM mass - differences in local urban air quality among three zones located very closely with different traffic intensity. The study was carried out in three different days by measuring simultaneously black carbon and PM mass concentrations with fixed monitoring stations located in three main radial roads connecting the outskirts to the city center, each with three segments: 1) an outer one, with no traffic restrictions 2) an intermediate one, subject to the congestion traffic charge called "Ecopass", where a ticket is required to enter for cars equipped with engines prior to Euro 4 standard; 3) the pedestrian zone (no cars admitted) of Duomo Square in the city center, where each of the three main roads ends. The results demonstrated a sharply declining gradient in black carbon levels from the outer zone, without traffic restrictions, to the more central areas, for all of the three radial main roads. The differences in mean black carbon levels in the same day in the different traffic scheme locations were highly significant for each comparison. In contrast to the Black carbon results, mean PM 10, PM 2.5, PM 1 concentrations did not show significant differences among the different traffic zones on the different campaign days. The ratio of black carbon to PM 10 decreased by 47% and 62% in the Ecopass zone and in the pedestrian zone, respectively, as

  3. An environmental, economical and socio-political analysis of a variety of urban air-pollution reduction policies for primary PM10 and NOx: The case study of the Province of Milan (Northern Italy)

    International Nuclear Information System (INIS)

    Chiesa, M.; Perrone, M.G.; Cusumano, N.; Ferrero, L.; Sangiorgi, G.; Bolzacchini, E.; Lorenzoni, A.; Ballarin Denti, A.

    2014-01-01

    Highlights: • PM10 and NO x emission reduction by different policies have been estimated. • Various actions have been considered, in the transport and residential sectors. • Environmental, economic and socio-political data were jointly evaluated. • Results are reported for the case study of the Province of Milan (Northern Italy). • Bike use fostering best matches cost–benefit results and socio-political acceptance. - Abstract: In the frame of urban air-pollution reduction policies, economic costs and environmental benefits of a variety of actions have been quantitatively assessed for the Province of Milan (Northern Italy), focusing on PM10 and NO x emission sources. Short-to-mid-term interventions that have been taken into consideration include reduction of inner temperature in residential buildings, banning of residential biomass heating systems, banning of diesel fuelled domestic boilers, night-time streets washing, speed limit reduction on highways, circulation restrictions of oldest EURO vehicles, conversion of diesel buses to natural gas, car sharing/biking promotion, DPF adoption in diesel vehicles, extension of road lanes for urban buses, energy efficiency refurbishment in residential buildings. Re*sults emerged from the cost–benefit analysis integrated with socio-political indicators obtained through direct surveys, will contribute, with an holistic and multidisciplinary approach, to drive the local administrators to implement the most suitable actions in one of the most polluted areas in west-Europe

  4. Groundwater restoration long beyond closure at the Homestake-Milan and United Nuclear-Church Rock uranium mill tailings piles, New Mexico, USA: full-scale programs requiring more than 20 years of active treatment

    International Nuclear Information System (INIS)

    Robinson, W.P.

    1998-01-01

    Since as early as 1975, groundwater contamination from New Mexico uranium mill tailings has been investigated with two sites -Homestake-Milan and United Nuclear-Church Rock -showing severe enough groundwater damage to merit listing on the US Environmental Protection Agency's (EPA) Superfund National Priority List -a nationwide list based on severity of pollution and water resource usefulness. These two sites provide valuable case studies for the first - 1950s -and second - 1970s -generations of uranium mill tailings facilities demonstrating the severity of contamination which ineffective control can allow and the challenge of full scale groundwater restoration. While the groundwater restoration at these sites began in the 1970s and 1980s, active treatment is anticipated into the 21st century. This paper summarizes the groundwater restoration programs at two of these sites - Homestake Mining Company's (HMC) Milan Mill (now called the ''Grants Project'') and United Nuclear Corporation's (UNC) Church Rock Mill. The two sites are summarized with respect to operations, groundwater impact, tailings disposal systems, hydrogeological characteristics of the site and affected areas, applicable standards, and remedial technology applied. This review provides a basis for initial comparisons with uranium mill tailings groundwater restoration challenges outside the USA. These sites provide an important benchmark the complexity of restoration at for large-scale uranium mill tailings sites. The longevity of the restoration efforts demonstrate the results of low-intensity responses to contamination upon detection and delayed enforcement actions. These ''witnesses'' to the value of effective pollution prevention in tailings design and full review and monitoring of tailings operations, have potential to be models of effective groundwater restoration. (orig.)

  5. Selected Lectures of the XXIII National Congress of the Italian Society of Neonatology (Società Italiana di Neonatologia, SIN; Milan (Italy; September 25-28, 2017

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2017-09-01

    Full Text Available Selected Lectures of the XXIII National Congress of the Italian Society of Neonatology (Società Italiana di Neonatologia, SIN; Milan (Italy; September 25-28, 2017Guest Editor: Mauro StronatiLECT 1. COMPLEMENTARY FEEDING IN PRETERM IN­FANTS: MYTHS AND FACTS • A. AcetiLECT 2. NEONATAL HYDRONEPHROSIS • R. AgostinianiLECT 3. WHEN A NEWBORN DIES IN NICU • M. Susi, S. Dosso, A. Anselmi, A. Bertolini, P. BibanLECT 4. RED REFLEX TESTING IMPLEMENTATION IN THE NURSERY: COMPARING EXPERIENCES • G. Araimo, S.G. Osnaghi, M. Colombo, G. Regiroli, L. Colombo, F. MoscaLECT 5. PAIN MANAGEMENT IN PREMATURE IN­FANTS. PAIN SEMIOLOGY AND ASSESS­MENT. ANALGESIA FOR SKIN BREAKING PROCEDURES • I. ArengaLECT 6. VISUAL EVOKED POTENTIALS: WHY AND WHEN PERFORM THEM • A. Baldascino, G. Amorelli, D. Lepore, F. Molle, G. D’Amico, A. CaporossiLECT 7. NURSING NEONATES SUPPORTED ON ECMO: ORGANIZATIONAL FEATURES AND CARING ASPECTS • C. Baracetti, G. Cavallaro, G. Raffaeli, L. Plevani, F. MoscaLECT 8. NEONATAL HYPO- AND HYPERGLYCEMIA: WHAT TO KNOW, WHAT TO DO • G. Barera, G. CassanoLECT 9. THE ESSENTIAL CARE LEVELS: INDICATIONS FOR THE NEWBORN • S. BattilomoLECT 10. VITAMIN D: OLD AND NEW • A. Boldrini, M. Del PistoiaLECT 11. NURSING-SENSITIVE OUTCOMES IN NEONA­TOLOGY • L. Boni, G. GarganoLECT 12. REQUIREMENTS OF MACRONUTRIENTS AND MINERALS IN PARENTERAL NUTRITION OF PRE­TERM INFANTS • V. Bozzetti, P.E. TagliabueLECT 13. KANGAROO MOTHER CARE (KMC AND NEU­ROPROTECTION • G. Calciolari, C. Artese, N. Bertoncelli, E. Beccaria, V. Chiandotto, G. Colombo, S. De Marca, R. Montirosso, G. Paterlini, N. Simeone, F. FerrariLECT 14. HEMODYNAMIC PRINCIPLES AND MANAGE­MENT OF EXTRACORPOREAL MEMBRANE OXYGENATION SUPPORT • F. Canesi, F. Conigliaro, R. Fierro, G. Cavallaro, G. Raffaeli, F. MoscaLECT 15. THE STABILIZATION OF THE NEWBORN BEFORE THE TRANSPORT • V. Cardilli, P. Repole, S. Caoci, R. CellittiLECT 16. NEONATAL EXTRACORPOREAL MEMBRANE OXYGENATION

  6. The introduction of electric vehicles in the private fleet: Potential impact on the electric supply system and on the environment. A case study for the Province of Milan, Italy

    International Nuclear Information System (INIS)

    Perujo, Adolfo; Ciuffo, Biagio

    2010-01-01

    The study analyses the possible impact of the electric vehicles' recharging activities on the electric supply system for the Province of Milan and on the global environment with a 2030 time horizon. In particular, the impact on the electric grid is seen both in terms of total electric energy consumption and in power requested to the grid. Because of the long recharging time required by the car batteries, the probability to have thousands of cars contemporary plugged-in at a given time is not negligible. On the other hand, the impact on the environment is seen in terms of CO 2 emissions reduction. Even if, at the moment, the Italian electric energy mix is mainly generated by means of thermal power stations making use of not renewable fossil fuels, the efficiency of these plants is much higher than the efficiency of a vehicle's engine. Results obtained clearly show that electric vehicles can contribute to the overall CO 2 abatement strategy in the transport sector but at the same time without an appropriate regulation (e.g. the intelligent integration of electric vehicles into the existing power grid as decentralised and flexible energy storage asset), electric vehicles could heavily impact on the daily requested electric power.

  7. Chemically and size-resolved particulate matter dry deposition on stone and surrogate surfaces inside and outside the low emission zone of Milan: application of a newly developed "Deposition Box".

    Science.gov (United States)

    Ferrero, Luca; Casati, Marco; Nobili, Lara; D'Angelo, Luca; Rovelli, Grazia; Sangiorgi, Giorgia; Rizzi, Cristiana; Perrone, Maria Grazia; Sansonetti, Antonio; Conti, Claudia; Bolzacchini, Ezio; Bernardi, Elena; Vassura, Ivano

    2018-01-19

    The collection of atmospheric particles on not-filtering substrates via dry deposition, and the subsequent study of the particle-induced material decay, is trivial due to the high number of variables simultaneously acting on the investigated surface. This work reports seasonally resolved data of chemical composition and size distribution of particulate matter deposed on stone and surrogate surfaces obtained using a new method, especially developed at this purpose. A "Deposition Box" was designed allowing the particulate matter dry deposition to occur selectively removing, at the same time, variables that can mask the effect of airborne particles on material decay. A pitched roof avoided rainfall and wind variability; a standardised gentle air exchange rate ensured a continuous "sampling" of ambient air leaving unchanged the sampled particle size distribution and, at the same time, leaving quite calm condition inside the box, allowing the deposition to occur. Thus, the "Deposition Box" represents an affordable tool that can be used complementary to traditional exposure systems. With this system, several exposure campaigns, involving investigated stone materials (ISMs) (Carrara Marble, Botticino limestone, Noto calcarenite and Granite) and surrogate (Quartz, PTFE, and Aluminium) substrates, have been performed in two different sites placed in Milan (Italy) inside and outside the low emission zone. Deposition rates (30-90 μg cm -2  month -1 ) showed significant differences between sites and seasons, becoming less evident considering long-period exposures due to a positive feedback on the deposition induced by the deposited particles. Similarly, different stone substrates influenced the deposition rates too. The collected deposits have been observed with optical and scanning electron microscopes and analysed by ion chromatography. Ion deposition rates were similar in the two sites during winter, whereas it was greater outside the low emission zone during summer and

  8. [The Medical Collections of Milan major hospital].

    Science.gov (United States)

    Galimberti, Paolo M

    2009-01-01

    This essay shows the uncommon occurrence of collections developed in a Hospital. In the past centuries the obstetrical gynaecological (since 18th Century) and anatomical collections (since 1829) were oriented to medical education, while the Pharmacy had a rich equipment. In the first half of 20th century, a Museum open to the public was planned, but the second World War and the absence of interest induce the loss of a large part of the materials. Since 2002 we had censed, collected, and listed the historical instruments, and in 2005 we realized a permanent exhibition. The collections combine about 1500 items. We have especial care to save also modern objects and equipments, after they are disused. At last we hope to realize a real Museum, and we search to assume peculiarities, goals, strength, potentials users, custom.

  9. Technology overview: SonoVue (Bracco, Milan).

    Science.gov (United States)

    Greis, Christian

    2004-10-01

    Ultrasound contrast agents introduced to sonography the possibility to demonstrate microvascular organization and parenchymal perfusion. In combination with modern contrast-specific imaging modalities, contrast agent signals can be separated from tissue-derived signals, allowing the detection of extremely small quantities of contrast agent. The following article describes the physical principles for the creation of contrast-specific signals, the particular physicochemical characteristics of SonoVue, a second-generation ultrasound contrast agent, and the resulting possibilities for the assessment of physiological functions.

  10. Exploring Academic Entrepreneurship in the Milan Area

    Science.gov (United States)

    Colapinto, Cinzia

    2011-01-01

    Academic entrepreneurship has become an increasingly important means by which universities can contribute to the economic development of a country. In Italy, universities have produced more than 700 academic spin-off companies in the last ten years. This paper uses case studies to develop an understanding of the key factors that underpin the…

  11. Nash tshelovek v Milane / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2006-01-01

    Eesti Kunstiakadeemia tööstusdisaini eriala III kursuse tudeng Pavel Sidorenko sai I koha ja kursusekaaslane Anna-Maria Einla II koha noorte disainerite konkursil Massimo Martini Design Award Milanos. Konkursi korraldusest, Sidorenko ja Einla konkursitöödest

  12. O Lugar da Leitura Silenciosa e da Leitura Oral na vida de Ambrósio, Bispo de Milão (Século IV d. C. * The Place of Silent Reading and Oral Reading in the Life of Ambrose, Bishop of Milan (Fourth-Century A.D.

    Directory of Open Access Journals (Sweden)

    JANIRA FELICIANO POHLMANN

    2014-02-01

    Full Text Available Resumo: Neste artigo nos propomos a relacionar elementos próprios da leitura silenciosa e da leitura oral na vida de Aurélio Ambrósio, bispo da cidade de Milão entre os anos de 374 e 397. Também aproveitamos a oportunidade para esclarecer algumas funções episcopais assinaladas por Ambrósio, especialmente a tarefa de ensinar. Para tanto, entre as obras examinadas para a execução deste trabalho, ressaltamos De Officiis Ministrorum Libri Tres e Exameron, de autoria do próprio bispo milanês, e o livro Confessionis de Agostinho, discípulo de Ambrósio.Palavras-chave: Ambrósio – Bispo – Leitura silenciosa. Abstract: In this article we propose to relate elements own of silent reading and reading oral in the life of Aurelius Ambrosius, bishop of the city of Milan between the years of 374 and 397. Also took the opportunity to clarify some episcopal functions signaled by Ambrosius, specially the task of teaching. For the achievement of our goals, we mainly examined De Officiis Ministrorum Libri Tres and Exameron, authored by own bishop milanese, and the book Confessionis of Augustinus, disciple of Ambrosius.Keywords: Ambrosius – Bishop – Silent reading.

  13. Excursion to Milan with Cisalpino and Carlson Wagonlit Travel

    CERN Multimedia

    2009-01-01

    Special offer for CERN staff and their family. Offer valid: - from 20th May to 12th July 2009 (last return) - only in first class - on direct trains from Geneva or Lausanne Return price per person: CHF 146.00 from Geneva CHF 130.00 from Lausanne Conditions : - reservation only via Carlson Wagonlit Travel, CERN - return reservation compulsory - reservation at least 3 days before departure - tickets are not changeable and not refundable - CWT agency fee not included: CHF 25.00 per order - maximum 4 persons per order - no other reduction possible - limited number of seats Enjoy your lunch in an exclusive and traditional place : in the 1st floor of "Zucca in Galleria" http://www.caffemiani.it EUR 44.00 per person (instead of about 80 Euros) Included: Aperitif, antipasti, main dish, dessert, wine/water, coffee. (Closed on Mondays) Reservation: mailto:business@cisalpino.com

  14. 3Demonstration Results of Phytoremediation of Explosives-Contaminated Groundwater Using Constructed Wetlands at the Milan Army Ammunition Plant, Milan, Tennessee Volume III.

    Science.gov (United States)

    1998-12-01

    Method 410.4 (Colorimetric, Automated; Manual)", Methods for Chemical Analysis of Water and Wastes - Revised March 1983, (U. S.) Enviromental ...organochlorine pesticides plus PCBs exceeds 0.30 /xg/g wet weight. (For analytical methods see USEPA, 1982). 61 11.6.16.3 Artemia nauplii are obtained as

  15. An ‘archaeological excavation’ in the Milan Central Station. Architecture and narration in the Memorial of the Shoah of Milan

    Directory of Open Access Journals (Sweden)

    Guido Mario Morpurgo

    2016-06-01

    In this sense, the station becomes the subject of a critical modification through an imaginary and physical excavation that reveals the immense, ‘total’ solidity of this archaeological find of our time. The project offers a new interpretation of correspondence between a plan and a construction system using a ‘principle of distancing’, a physical and temporal gap between the new parts and the ‘remains’. By reworking all the elements of the station – through a process of reassembling – the project witnesses to the tragedy of the Shoah, without any further comment. Through the critical interpretation of the document-monument, architecture reaffirms the ethical dimension of memory. Keywords: Memory, Narration, Archaeology, Distancing, Assemblage

  16. The Use of Constructed Wetlands to Phytoremediate Explosives-Contaminated Groundwater at the Milan Army Ammunition Plant, Milan, Tennessee. Cost and Performance Report

    National Research Council Canada - National Science Library

    1999-01-01

    .... To help address this problem, the USAEC and TVA initiated a field demonstration program to evaluate the technical feasibility of using constructed wetlands for remediating explosives-contaminated groundwater...

  17. INVITACION AL TEATRO DE MILAN. LAS LOCALIDADES DE EL MUNDO COMO VOLUNTAD Y REPRESENTACION

    OpenAIRE

    BAQUEDANO JER, SANDRA; BAQUEDANO JER, SANDRA

    2003-01-01

    Establecidos los marcos pertinentes de la metáfora del teatro y de las marionetas, presente a lo largo de toda la obra de Schopenhauer, el lector se encuentra en condiciones de entrar al teatro de Milán. El acceso de la puerta principal es la crítica orteguiana hecha al idealismo que permite reconocer el singular aspecto del teatro de Milán, distinguiéndose de cualquier otra instancia filosófica o estética donde representarnos metafóricamente el pensamiento del idealismo. Invitación ...

  18. Marginal Uncertainties Making a Living and Working on the Outskirts of Milan

    Directory of Open Access Journals (Sweden)

    Giacomo Pozzi

    2017-07-01

    Full Text Available In this article we question the meanings and social practices related to living and working in the Social Housing neighbourhoods of Milan’s present-day suburbs. Through the reconstruction of several narratives, we shed light on how uncertainty characterises the professional everyday lives of those social actors who play a particularly significant role in Milan’s complex arena of social housing management (social workers; bailiffs; inspectors; “trouble-solvers”. Isolation, neglect and conflict are the main terms used by the social actors, both to describe the ongoing housing precarity of those who are at risk of losing their homes and to frame the current conditions of social housing. These represent crucial interpretative keys for developing a thick understanding of the housing crisis.

  19. An optimal management of water for a turf irrigation system in Milan area (Italy)

    Science.gov (United States)

    Deangelis, Maria Laura; Mazzoleni, Abramo

    2015-04-01

    The design of an irrigation system is not just "draw", but a complex organization that takes into account of a whole range of information that are inherently contained in the graphic representation of the final plan. The various stages that make up the activity of designing an irrigation system include: general survey of the site to be irrigated, meteorological analysis of the site and the calculation of the water requirement, development of the project with the choice and location of the components. The use of a numerical model based on water balance in a soil-water-atmosphere system allows the evaluation of the optimal water requirement as a function of meteorological characteristics. The water saving is enabled through a smart programming of a modern automation system for irrigation. The meteorological data analysis was conducted choosing from the series of two special years: the year 2002, particularly rainy, and the other in 2007, extraordinarily drought. The determination of the water requirements of turf was conducted on a daily scale. The water consumption was calculated in a classic irrigation system that covers the delivery of 5 mm of water per day, interrupted only by a rain sensor. In the second case water consumption was analysed by managing an irrigation controller based on actual water needs of turf day by day. For the two years in question water savings ranges between 13 and 27%.

  20. Milan Army Ammunition Plant. Remedial Investigation Report. Volume 4. Appendices M - T

    Science.gov (United States)

    1991-12-01

    5,000 12,500 Selenium SE 0.25 3.02 10 100 Silver AG 2.5 4.6 50 2,500 Sodium NA 150.0 500 5,000 50,000 Thallium TL 31.3 81.4 5,000 40,000 Vanadium V 0.775...fibrotic peritonitis, respectively (NAS 1982). Evidence to date suggests that aluminum is not teratogenic or fetotoxic; however, rats exposed by gavage to...dermal lesions, and cardiovascular damage (EPA 1984, Tseng 1977). Arsenic is embryotoxic, fetotoxic, and teratogenic in several animal species (EPA

  1. Enterovirus D68-associated community-acquired pneumonia in children living in Milan, Italy

    NARCIS (Netherlands)

    Esposito, Susanna; Zampiero, Alberto; Ruggiero, Luca; Madini, Barbara; Niesters, Hubert; Principi, Nicola

    Background: An increasing number of children infected by enterovirus D68 (EV-D68) and affected by severe respiratory illness, muscle weakness and paralysis were described in the USA and Canada in 2014 Objectives: To investigate the potential involvement of EV-D68 in determining community-acquired

  2. Personal exposure to airborne ultrafine particles in the urban area of Milan

    International Nuclear Information System (INIS)

    Cattaneo, A; Garramone, G; Taronna, M; Peruzzo, C; Cavallo, D M

    2009-01-01

    The relevance of health effects related to ultrafine particles (UFPs; aerodynamic diameter 5 particles/cm 3 . UFPs measures were divided on the basis of crossed environments or micro-environments, days of the week and day time (hours). The highest measured mean concentrations and data variability were observed during walking time and moving on motorized vehicles (bus and car), indicating that the highest exposure to UFPs can be reached near motorized traffic. The lowest exposures were observed in green areas and in office microenvironments. An appreciable difference between working and non-working days was observed. Concentration patterns and variation by days of the week and time periods appears related to time trends in traffic intensity.

  3. La dimension symbolique du capital social: les grandes cercles et Rotary clubs de Milan

    NARCIS (Netherlands)

    Cousin, B.; Chauvin, S.

    2010-01-01

    Les cercles et clubs bourgeois des métropoles européennes ont jusqu'ici surtout fait l'objet de monographies isolées. Le cas milanais permet de passer à une analyse relationnelle : les institutions de gestion collective du capital social des classes dominantes y forment en effet un espace de jeu et

  4. “The Milan Papyrus” – Seminal Discovery of New Hellenistic Verses

    Directory of Open Access Journals (Sweden)

    Jelena Isak Kres

    2006-07-01

    Full Text Available The publication of some newly discovered poems, probably to be attributed to the Hellenistic epigrammatist Posidippus of Pella, is the most significant recent contribution to the corpus of Greek literature. The sheer amount of the poetry and the light which it sheds on our understanding of the literary period makes it the most important discovery in decades, comparable to the papyrus discoveries of Bacchylides, Menander, and Sappho. Moreover, the text is considered to be the earliest collection of Greek poetry organised on aesthetic principles.

  5. Two Monumental Bases in Piazza del Duomo and Via Mercanti in Milan

    Directory of Open Access Journals (Sweden)

    Dario Daffara

    2017-10-01

    Full Text Available In questo articolo vengono presentati materiali d’archivio inediti su due basamenti monumentali di epoca imperiale scoperti in piazza del Duomo e in via Mercanti. Le modalità della scoperta e la quasi totale scomparsa dei resti archeologici rendono problematico stabilire la reale funzione di questi basamenti, realizzati con tecnica simile e verosimilmente per la stessa funzione. Nel corso degli anni sono state avanzate diverse ipotesi di attribuzione (torri medievali, archi onorari, tetrapili, monumenti onorari; grazie a un gran numero di confronti sono stati esclusi i meno plausibili, arrivando alla conclusione che probabilmente i due basamenti furono realizzati in epoche diverse in corrispondenza dell’antico limite della città pre-romana, forse per sostenere gruppi statuari o colonne onorarie.

  6. Designing MOOCs in Higher Education. Outcomes of an experimentation at the Catholic University of Milan

    Directory of Open Access Journals (Sweden)

    Ferrari Simona

    2015-06-01

    Full Text Available This article aims to describe the meaning and pedagogical reasons for MOOCs (Massive Open Online Courses utilisation in higher education. Initially, we consider the situation in the Italian education, where MOOCs usually were used as tools for the universities’ marketing strategies. Knowing this, Catholic University built the MOOC on Digital Virtues for imaging a new way of thinking about these kinds of formative activities. The results are interesting in terms of dropout rates, branding and customer satisfaction. The key, as the survey we present in this article shows, is quality and reputation.

  7. Signoles Aude, Le Hamas au pouvoir et après ?, Toulouse, Editions Milan, 2006.

    Directory of Open Access Journals (Sweden)

    Jean-François Legrain

    2007-11-01

    Full Text Available Dans les étroites limites imposées par la collection (absence totale de notes et de bibliographie, 112 p. en format réduit, le petit livre d’Aude Signoles, Le Hamas au pouvoir et après ?, commence à combler un vide de l’édition française. Le seul livre jusque là disponible en français et entièrement consacré à Hamas remonte à 7 années maintenant ; doté de nombreuses erreurs factuelles et faisant comme si Hamas était apparu avec l’autonomie des années 1990, il ignorait tout de son passé d’Ass...

  8. The management of ductal intraepithelial neoplasia (DIN): open controversies and guidelines of the Istituto Europeo di Oncologia (IEO), Milan, Italy.

    Science.gov (United States)

    Farante, Gabriel; Zurrida, Stefano; Galimberti, Viviana; Veronesi, Paolo; Curigliano, Giuseppe; Luini, Alberto; Goldhirsch, Aron; Veronesi, Umberto

    2011-07-01

    The management of ductal intraepithelial neoplasia (DIN) has substantially changed over the past 30 years, as its incidence has increased (from 2-3% to more than 20%), mainly due to the widespread use of mammography screening. This article describes not only the more widespread theoretical concepts on DIN but also the differences in the practical applications of the theory between different countries, different oncology specialists, and different cancer centers. Papers related to the international multicentre-randomized trials and retrospective studies were analyzed. We include articles and papers published between 1993 and 2010 related to patients with DIN, and abstracts and reports from MEDLINE and other sources were indentified. The standard of care for DIN consists of (a) breast conservative surgery (mastectomy is still indicated in large lesions--masses or microcalcifications--in about 30% of cases); (b) radiotherapy (RT) after conservative surgery, and (c) medical treatment in estrogen receptors-positive patients. However, most studies have shown significant differences between theory and practical application. Moreover, there are differences regarding (a) the indications of sentinel lymph node biopsy, (b) the definition and identification of low-risk DIN subgroups that can avoid RT and tamoxifen, and (c) the research into new alternative drugs in adjuvant medical therapy. A general agreement on the best management of DIN does not exist as yet. New large trials are needed in order to define the best management of DIN patients which is (in most respects) still complex and controversial.

  9. MILANO ARCHEOLOGIA FOR EXPO 2015. TOWARDS A VALORIZATION OF THE ARCHAEOLOGICAL HERITAGE OF THE CITY OF MILAN

    Directory of Open Access Journals (Sweden)

    Daniela Massara

    2015-06-01

    Full Text Available Si pubblicano qui le relazioni presentate durante il seminario interdisciplinare e interateneo dal titolo “Milano Archeologia per Expo 2015. Verso una valorizzazione del patrimonio archeologico della città di Milano”. Il seminario è stato organizzato come parte integrante del progetto “Milano Archeologia per Expo 2015”, avviato nel 2013, il quale ha avuto tra i suoi scopi quello di incrementare conoscenza, consapevolezza e quindi visibilità dei resti della Milano romana attraverso specifici strumenti di didattica e divulgazione. Il workshop si pone infatti a conclusione di un percorso destinato in particolare ai milanesi ed esteso a tutti gli interessati, condotto durante tutta la durata del progetto. Ne sono un esempio le conferenze svoltesi al Civico Museo Archeologico di Milano: giovani studiosi hanno presentato a un pubblico non specialistico i risultati delle loro ricerche su Mediolanum; la locandina del programma delle conferenze testimonia la varietà dei temi trattati.

  10. Setup of a sustainable indoor cleaning methodology for the sculpted stone surfaces of the Duomo of Milan

    OpenAIRE

    Gulotta, Davide; Saviello, Daniela; Gherardi, Francesca; Toniolo, Lucia; Anzani, Marilena; Rabbolini, Alfiero; Goidanich, Sara

    2014-01-01

    Cleaning is a fundamental phase of the conservation and maintenance activity of the cultural heritage. It is required to be highly effective in the removal of undesired deposits, controllable at every stage and gradable, selective, and completely respectful of the substrate. Moreover, cleaning procedures which can also assure to be harmless to the environment and the operators are particularly valued nowadays. According to these general guidelines, in the present work a sustainable approach f...

  11. Form to citizenship in the sign of empowerment of women. Reflections on the volume Educative Practices for Social Inclusion, edited by M. Striano, Franco Angeli, Milan 2010.

    Directory of Open Access Journals (Sweden)

    Valeria Napolitano

    2013-06-01

    Full Text Available The essay invites to read the book edited in 2010 by Maura Striano, Pratiche educative per l’inclusione sociale, focalising some international and European initiatives aimed at promoting lifelong learning interventions addressed to “weak” categories of peoples. Compared to these, is the adoption of a gender perspective, according to which the limited recognition of the rights of citizenship of women in terms of education, employment status and political participation is linked to symbolic discrimination of a culture called “universal”, but deeply rooted in male values.

  12. ["Assessment of indoor school environment and identification of measures to protect the respiratory health of school children and adolescents" in a sample of schools in Milan].

    Science.gov (United States)

    Piazza, S; Gulino, A; Pulvirenti, S; Vercelli, F; Carrer, P

    2012-01-01

    The management of indoor air quality in schools needs special attention because it has a strong impact on respiratory health of children with effects also on performance and social development. In Italy a prevention program for indoor environments is provided in the "Guidelines for the prevention of indoor risk factors for allergies and asthma in the school", developed by the Ministry of Health (G.U n. 9 del 13.01.11). In this context, the Ministry of Health has promoted the "Indoor school" project (CCM2010). The main objective of the project is the implementation of these guidelines. In this paper we report the results of the first phase of the project which assessed the knowledge of school principals on issues related to IAQ and building characteristics of the school.

  13. Autoria contra tradução ou tradução como autoria: Milan Kundera, Jorge Luis Borges e o fim do indivíduo.

    Directory of Open Access Journals (Sweden)

    Pere Comellas

    2010-04-01

    Full Text Available Translation has often been seen as an activity subordinate to creation. However, numerous works considered as by an author, even essential works in the literary canon, are very close to translation. Shakespeare recycled stories and Diderot translated Sterne in his own way. Can translation not be viewed as just another literary genre? This is the perspective defended by Borges, but strongly opposed by Kundera. Whereas Borges questions whether precedence has to mean pre-eminence, Kundera understands the crisis of authorship as an attack on the individual. Does the end of the submission of the translation necessarily have to be the end of the recognition of creativity?

  14. Transport and Fate of Nitroaromatic and Nitramine Explosives in Soils from Open Burning/Open Detonation Operations: Milan Army Ammunition Plant (MAAP)

    Science.gov (United States)

    1993-12-01

    columns to eliminate photodegradation processes). Controlled tension (vacuum) was applied equally at the bottom of each soil column across the controlled...R.J. Hemingway, W. Klein, D.B. Sharp, J.W. Vonk, and P.T. Holland. 1988. IUPAC Reports on Pesticides (24): Recommended approach to the evaluation of...the environmental behavior of pesticides . Pure & Appl. Chem. 60:901-932. 47 (10) Cabrera, M.L. and D.E. Kissel. 1988. Evaluation of a method to

  15. Electrical resistivity and induced polarization tomography in identifying the plume of chlorinated hydrocarbons in sedimentary formation: a case study in Rho (Milan - Italy).

    Science.gov (United States)

    Cardarelli, Ettore; Di Filippo, Gerardina

    2009-09-01

    Resistivity and induced polarization surveying were originally developed for mineral exploration but are now finding new applications in the field of environmental and engineering geophysics. The present article reports the results of a geophysical survey performed with the aim of identifying a plume of chlorinated hydrocarbons in sedimentary formations of the Pandania plain. The tested site is characterized by three sand and gravel aquifers containing a quantity of clay particles which influence the overall bulk resistivity and chargeability. According to data obtained using shallow boreholes, mainly dense non-aqueous phase liquids were found as contaminants in the first and second aquifer. The aforementioned geo-electrical methods were applied in both two- and three-dimensional approaches. Steel and copper electrodes were used in the process of field data acquisition and the results of the survey were compared. The geophysical survey revealed some anomalies that could be explained by the presence of dense non-aqueous phase liquids in the soil medium. The concept of normalized chargeability facilitates the interpretation of detected induced polarization anomalies. The shape of the plume was inferred from maps of resistivity and chargeability to a depth of 25 m below the surface of the ground.

  16. [Cardiovascular and hormonal strain in waste collection workers employed in Amsa SpA, municipality of Milan, in permanent day and night work].

    Science.gov (United States)

    Biggi, N; Consonni, D; Fragasso, G; Lattuada, G; Perseghin, G L; Verga, R; Costa, G

    2007-01-01

    Aim of the study is to explore in shiftworkers: a) blood pressure and hormonal variations; b) dyslipidemia and blood glucose levels; c) insulin resistence syndrome. We have assessed 48 male workers employes in Amsa SpA, a large municipal enterprise in charge of street cleaning and domestic waste collection, in permanent day and night work as hand sweepers, motor sweepers and delivery tricar drivers. 24 of those workers (daily and nightly) were normotensive and 24 were hypertensive. Our medical checks were: physical examination: BMI; laboratory findings (blood): glucose, total cholesterol, triglycerides, endothelin, insulin, FFA, HOMA S, HOMA B, HOMA R; assay of salivary cortisol and urinary cortisol in 24 h; 24 h pressure monitoring. Nightly hypertensive: increased consumption in wine and coffee, weight and BMI, total cholesterol and FFA and endothelin. Nightly normotensive: increased consumption in cigarettes and salivary cortisol. Daily hypertensive: increased total cholesterol; 24 h pressure monitoring showed more pronounced variations of pressure in night workers both normotensive and hypertensive in working time. Night shiftwork looks like more stressfull than day shiftwork. Insuline resistance isn't noticed in all four groups.

  17. The Milan Project: A New Method for High-Assurance and High-Performance Computing on Large-Scale Distributed Platforms

    National Research Council Canada - National Science Library

    Kedem, Zvi

    2000-01-01

    ...: Calypso, Chime, and Charlotte; which enable applications developed for ideal, shared memory, parallel machines to execute on distributed platforms that are subject to failures, slowdowns, and changing resource availability...

  18. Implementation of the Dutch Meeting Centres Support Program for people with dementia and their carers in Milan: process evaluation of the preparation phase.

    NARCIS (Netherlands)

    Westerman, Marjan J.; Farina, E.; van der Sanden, M.C.; Saibene, F.L.; Meiland, F.J.M.; Droes, R.M.; Chattat, R.

    2016-01-01

    Background & Aims: The Meeting Centres Support Programme (MCSP) for people with mild to moderately severe dementia and their carers proved effective in the Netherlands, and is now being implemented in other European countries. This study aimed to compare factors that at the preparation of two

  19. Capabilities of R Package mixAK for Clustering Based on Multivariate Continuous and Discrete Longitudinal Data

    Directory of Open Access Journals (Sweden)

    Arnošt Komárek

    2014-09-01

    Full Text Available R package mixAK originally implemented routines primarily for Bayesian estimation of finite normal mixture models for possibly interval-censored data. The functionality of the package was considerably enhanced by implementing methods for Bayesian estimation of mixtures of multivariate generalized linear mixed models proposed in Komrek and Komrkov (2013. Among other things, this allows for a cluster analysis (classification based on multivariate continuous and discrete longitudinal data that arise whenever multiple outcomes of a different nature are recorded in a longitudinal study. This package also allows for a data-driven selection of a number of clusters as methods for selecting a number of mixture components were implemented. A model and clustering methodology for multivariate continuous and discrete longitudinal data is overviewed. Further, a step-by-step cluster analysis based jointly on three longitudinal variables of different types (continuous, count, dichotomous is given, which provides a user manual for using the package for similar problems.

  20. De Milán a Palermo: la aplicación de mecanismos internacionales para enfrentar a la delincuencia organizada transnacional/From Milan to Palermo: the implementation of international mechanisms to deal with transnational organized crime

    Directory of Open Access Journals (Sweden)

    Rubén Cardoza Zúñiga (México

    2013-08-01

    Full Text Available Actualmente, la delincuencia organizada transnacional afecta a toda la comunidad internacional, por lo tanto estamos ante un problema que va más allá de las fronteras de cada Estado. En consecuencia, el modo idóneo para enfrentar esta situación es buscar soluciones de índole multilateral. Por esta razón, dicha comunidad ha adoptado una serie de mecanismos a nivel mundial, los cuales sirven de fundamento para crear estrategias, tanto nacionales como internacionales, para enfrentar la mencionada delincuencia. Currently, transnational organized crime affects the international community, therefore we are faced with a problem that goes beyond the borders of each State. Mode suitable to deal with this situation is therefore seeking solutions of a multilateral nature. For this reason, the community has adopted a series of mechanisms at the global level, which serve as a basis to create strategies, both national and international, to face the mentioned delinquency.

  1. 3D-conformal radiation therapy in prostate cancer. Technical considerations after 5 years of experience and 334 patients treated at the Istituto Europeo di Oncologia of Milan, Italy.

    Science.gov (United States)

    Ghilezan, M; Ivaldi, G; Cattani, F; Greco, C; Castiglioni, S; Leonardi, M C; Tosi, G; Marsiglia, H; Orecchia, R

    2001-01-01

    To report the technique of 3D-conformal radiation therapy (3D-CRT) currently used at our Institute for the treatment of prostate cancer with a curative intent. A critical review of the technical aspects of the technique is provided. Between December 1995 and October 2000, 334 patients with biopsy-proven adenocarcinoma of the prostate were treated with 3D-CRT. All patients were treated in a prone position with 15 MV X-ray beams and a 6-field technique for all but 20 patients, who were treated with a 3-field technique. Patients were simulated with the rectum and bladder empty. To ensure reproducible positioning, custom-made polyurethane foam or thermoplastic casts were produced for each patient. Subsequently, consecutive CT scan slices were obtained. The clinical target volume and critical organs (rectum and bladder) were identified on each CT slice. The beam's eye view technique was used to spatially display these structures, and the treatment portals were manually shaped based on the images obtained. The beam apertures were initially realized by conventional Cerrobend blocks (48 patients), which were replaced in October 1997 by a computer-driven multi-leaf collimator. The total target dose prescribed at the ICRU point is 76 Gy, delivered in 38 fractions and 54 days. The seminal vesicles are excluded at 70 Gy. Dose-volume histograms were obtained for all patients. If more than 30% of the bladder and/or more than 20% of the rectum receive >95% of the prescribed total dose, the treatment plan is judged as unsatisfactory and is adjusted. The dose-volume histogram can be improved by changing the beam's arrangement and/or weights or by introducing or modifying the wedge filters. 3D-CRT in prostate cancer patients is a highly sophisticated and time-consuming method of dose delivery. Important technical issues remain to be clarified.

  2. Long-term outcomes following mini-crush versus culotte stenting for the treatment of unprotected left main disease: Insights from the milan and New-Tokyo (MITO) registry.

    Science.gov (United States)

    Kawamoto, Hiroyoshi; Takagi, Kensuke; Chieffo, Alaide; Ruparelia, Neil; Yusuke Fujino; Yabushita, Hiroto; Watanabe, Yusuke; Latib, Azeem; Carlino, Mauro; Montorfano, Matteo; Nakamura, Sunao; Colombo, Antonio

    2017-01-01

    This study aimed to investigate the long-term outcomes following mini-crush versus culotte stenting with drug-eluting stents (DES) for the treatment of unprotected left main coronary artery (LMCA) disease. Both mini-crush and culotte stenting are considered efficacious treatment options when a planned 2-stent strategy is deemed necessary for unprotected LMCA disease. However, there are limited data available with regard to the long-term clinical outcomes of each strategy in this setting. Between July 2002 and November 2013, 225 patients were identified. 135 patients were treated with the mini-crush technique, and 90 patients with culotte stenting. The median follow-up period was 1,263 (IQR 820-1,847) days. The mini-crush group had worse lesion and procedural characteristics when compared to the culotte group. There were no significant differences in major adverse cardiac events (MACE) at 5 years (mini-crush 36.0% vs. culotte 41.4%, P = 0.57). Myocardial infarction (MI) and definite stent thrombosis (ST) occurred significantly higher (MI; 0 vs. 11.3%, log-rank P = 0.003, and definite ST; 0 vs. 6.3%, log-rank P = 0.02, respectively) in the culotte group. Cox regression analysis indicated that full stent coverage of the LMCA and SYNTAX score were independent predictors for MACE. The incidence of MACE and overall TLR were comparable between groups. However, the rates of MI and definite ST were significantly higher in the culotte group. Full stent coverage of the LMCA may reduce the incidence of MACE when a two-stent strategy is used for the treatment of unprotected LMCA disease. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. The temple crematorium in the Monumental Cemetery in Milan Considerations on the project of the Memorial stone to the fallen in the forest of Cercina Edoardo Detti and Carlo Scarpa

    Directory of Open Access Journals (Sweden)

    Francesca Mugnai

    2015-12-01

    Full Text Available In the 60s Edoardo Detti and Carlo Scarpa design a memorial headstone in memory of seven supporters killed by the Germans in 1944, which was to be built in Cercina near Florence. The only remains of this small monument are some sketches by Scarpa and a finalized drawing by Detti, little known but very interesting, which document the compositional research of the laic expression, pluralistic of death and pain, as a universal answer, inclusive and non-dogmatic, the need to represent the wounds of the war and their cargo of political, ethnic and religious lacerations. The search for universal symbolism, capable of comprehending the different souls of modern society, also belongs to individual architectural production of the two architects and is inscribed in the contemporary architectural and cultural context.

  4. Successful resection of hepatocellular cancer not amenable to Milan criteria and durable complete remission induced by systemic polichemotherapy after development of metastases - should we think about revising the current treatment guidelines in selected patients?

    Science.gov (United States)

    Rados, Ivana; Badzek, Sasa; Golem, Hilda; Prejac, Juraj; Gorsic, Irma; Kekez, Domina; Librenjak, Niksa; Plestina, Stjepko

    2013-09-22

    To refresh clinical diagnostic and therapeutic dilemmas in patients presenting with hepatocellular cancer (HCC) and to report a rare success of systemic polichemotherapy in metastatic HCC. Case report of a patient with successfully resected HCC although initially deemed inoperable according to current guidelines, and who was successfully treated by systemic polichemotherapy after development of metastatic disease, resulting in a sustained complete remission. We describe a 71-year-old female with HCC initially treated by atypical liver resection, although not amenable to initial surgery according to current treatment guidelines, which resulted in 6 months disease-free interval. After development of pulmonary metastases, the patient was treated by systemic polichemotherapy, due to local unavailability of novel biologic agents. After 3 months of chemotherapy biochemical remission was confirmed, and after 10 months of active treatment complete radiological remission was verified according to Response Evaluation Criteria in Solid Tumors (RECIST) criteria, now exceeding 9 months in duration. There is an increasing body of evidence that criteria for surgical interventions in HCC should be revised and expanded, and our case is an example of such an approach. Although novel biologic therapies are not widely available in all regions of the world due to their cost, currently there are no hard recommendations for use of chemotherapy in such areas. Since this is a large problem in clinical practice, we conclude that chemotherapy should be offered to selected patients of good performance status if novel agents are unavailable.

  5. [The consultation with the candidate couple for intracytoplasmic sperm injection (ICSI) using microsurgical epididymal sperm aspiration (MESA) or testicular sperm aspiration (TESA). The experience of the MATRIS (Medici Associati per la Terapia e la Ricerca dell'Infertilità e Sterilità) center of Milan].

    Science.gov (United States)

    Magro, B; Magro, S

    1998-04-01

    The authors examine the relationship between doctor and patient during the consultation for the therapeutic decision for those couples who have to undergo a medical procreation, especially the ICSI by MESA and TESA. The couple's psycho-emotional involvement and the medical terminology hinder the real possibility of communication between doctor and patient. The data relating to a study of 80 couples done by the authors are presented. They show the need to improve the quality of communication between doctor and patient during the consultation. For this purpose, on the basis of the research conducted, modification of the language used and the support of audio-visual media are suggested during the consultation in order to reduce the percentage of the couple's doubts and uncertainties.

  6. La differenza tra noi e “gli altri”: su alcune mostre coloniali milanesi organizzate nel Ventennio fascista / The difference between us and “the others”: notes on some colonial exhibitions in Milan during the “Ventennio” (the Fascist period

    Directory of Open Access Journals (Sweden)

    Silvia Colombo

    2016-12-01

    In this essay, the results obtained by the protagonists who worked for these shows – artists, architects, customers... – will be also considered, together with the didactic intentions illustrated by the team of organisers. In that way it will be possible to underline the communication instruments used by the regime in order to impress the public, to understand the key-role played by the exhibitions during the “Ventennio”; and, finally, to perceive the xenophobic perspective employed by the PNF to educate the masses in seeing “the others”.

  7. 78 FR 45593 - Bureau of European and Eurasian Affairs (EUR) Request for Proposals for the Fundraising...

    Science.gov (United States)

    2013-07-29

    ... the Steering Committee of the College of Commissioners General for Milan Expo 2015. With a projected... interests around the world. U.S. participation in Milan Expo 2015 will confirm the strength and importance... Safety Food and Health Research and Technology Food Education Sustainability Biodiversity Technologies...

  8. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Carmem L P S Zanta1 C A Martínez-Huitle2. Departamento de Química da Universidade Federal de Alagoas, Campus A.C. Simões, Tabuleiro do Martins, Maceió-AL 57072-970, Brazil; University of Milan, Department of Chemistry, Celoria 2, 20133 Milan, Italy ...

  9. 77 FR 75655 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2012-12-21

    ... County Peru High School Historic District, (Indiana's Public Common and High Schools MPS), 80 W. 6th St., Peru, 12001154 Ripley County Milan Masonic Lodge No. 31, 312 Main St., Milan, 12001155 NORTH CAROLINA... Duke, Estate, 1044 & 1050 W. Forest Hills Blvd., Durham, 12001157 Hertford County Uptown Suburbs...

  10. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Milan Kanti Naskar. Articles written in Journal of Chemical Sciences. Volume 120 Issue 1 January 2008 pp 181-186. Significant improvement in the pore properties of SBA-15 brought about by carboxylic acids and hydrothermal treatment · Milan Kanti Naskar M ...

  11. Stalin's Big Fleet Program

    National Research Council Canada - National Science Library

    Mauner, Milan

    2002-01-01

    Although Dr. Milan Hauner's study 'Stalin's Big Fleet program' has focused primarily on the formation of Big Fleets during the Tsarist and Soviet periods of Russia's naval history, there are important lessons...

  12. CSF Markers in Guillain-Barre Syndrome

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2007-01-01

    Full Text Available A positive 14-3-3 protein assay of CSF was observed in 29 of 38 patients with GBS and in 4 with motor neuron disease and other neuropathies studied at Universities of Milan and Verona, Italy.

  13. What Are the Treatments for Bacterial Vaginosis (BV)?

    Science.gov (United States)

    ... P., Gordon, A., Heatley, E., & Milan, S. J. (2013). Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2013 ... NICHD News Spotlights Getting to Know the New NICHD Director ...

  14. Předmluva k pátému číslu: Pocta Milanu Mrázovi

    Czech Academy of Sciences Publication Activity Database

    Boháček, Kryštof

    2011-01-01

    Roč. 3, č. 5 (2011), s. 1-8 ISSN 1803-7860 Institutional research plan: CEZ:AV0Z90090514 Keywords : Aither * Ancient Philosophy * medieval Philosophy * tribute to Milan Mraz Subject RIV: AA - Philosophy ; Religion

  15. "Ja lahkuda polnud kerge" : pisteline essee reetmisest / Tõnu Õnnepalu

    Index Scriptorium Estoniae

    Õnnepalu, Tõnu, 1962-

    2011-01-01

    Ka reetmise teemast kirjanduses: Milan Kundera romaanist "Olemise talumatu kergus", Louis-Ferdinand Céline'ist, Pierre Drieu La Rochelle'i Teise maailmasõja ajal kirjutatud päevikutest ja Jean Genet'st

  16. American Joint Helicopter Command: Addressing a Lack of Operational Control of Rotary Assets

    National Research Council Canada - National Science Library

    Marsowicz, Brandon

    2007-01-01

    ... to achieve unity of effort. Based on the tenets of operational command and control by Milan Vego, across all services, the United States helicopter forces fare lacking operational command and control...

  17. Observations on lead pollution in milk

    Energy Technology Data Exchange (ETDEWEB)

    Maffeo, G.; Renon, P.

    1976-08-01

    The problem of lead pollution in milk in highly industrialized areas (district of Milan) has been evaluated. Potentially dangerous rates of lead have been checked in milk, agricultural fields, fodders and entrails of slaughtered animals.

  18. Metabolic syndrome, inflammation and atherosclerosis

    OpenAIRE

    Rodolfo Paoletti; Chiara Bolego; Andrea Poli; Andrea Cignarella

    2006-01-01

    Rodolfo Paoletti1,2, Chiara Bolego1, Andrea Poli2, Andrea Cignarella1,31Department of Pharmacological Sciences, University of Milan, Italy; 2Nutrition Foundation of Italy (NFI), Milan; 3Department of Pharmacology and Anesthesiology, University of Padova, ItalyAbstract: The inflammatory component of atherogenesis has been increasingly recognized over the last decade. Inflammation participates in all stages of atherosclerosis, not only during initiation and during evolution of lesions, but also...

  19. Model Classes, Approximation, and Metrics for Dynamic Processing of Urban Terrain Data

    Science.gov (United States)

    2013-01-01

    Lawrence Livermore National Laboratory “Compressive Signal Processing,” Mohammed Dahleh Distinguished Lecture, UCSB "Greedy Algorithms in Banach Spaces ...in Banach Spaces ", Davinci Lecture Series, Milan, Italy, July 2012 "Greedy Algorithms in Banach Spaces ", Departmental Series, Aachen, Germany, July...sensing and Related Applica- tions, 12/2010, Seoul, Korea. R. DeVore, Greedy Algorithms in Banach Spaces , Davinci Lecture Series, Milan, Italy, July

  20. Tumor Biology as Predictor of Mortality in Liver Transplantation for Hepatocellular Carcinoma.

    Science.gov (United States)

    Caicedo, L A; Delgado, A; Duque, M; Jiménez, D F; Sepulveda, M; García, J A; Thomas, L S; Garcia, V H; Aristizabal, A M; Gomez, C; Arrunategui, A M; Manzi, E; Millan, M; Villegas, J I; Serrano, O; Holguín, A; Echeverri, G J

    2018-03-01

    Hepatocellular carcinoma (HCC) is the most frequent primary malignant liver tumor, with the Milan criteria considered to be the gold standard for patient selection for liver transplantation (LT). We performed a descriptive observational study, reviewing 20 years of experience of LT in patients with HCC in the Fundacion Valle del Lilí in Cali, Colombia. Subgroup analysis was undertaken for periods 1999 to 2007 and 2008 to 2015. Fifty-seven cases with a pretransplant HCC diagnosis were reviewed. In the first period patients within the Milan criteria had a recurrence-free survival at 5 years of 66.6%, and in those who exceeded the Milan criteria, recurrence-free survival was 75%. In the second period, patients within the Milan criteria, recurrence-free survival at 5 years was 93.5%, and in those who exceeded the Milan criteria, recurrence-free survival was 75.7%. No statistically significant difference was found in either period. For patients with mild and moderate tumor differentiation, the relapse survival rate at 5 years was 69.4% (95% confidence interval [CI] 35.8-87.8) and 74.7% (95% CI 44.5-90), respectively. All patients with poor tumor differentiation relapsed and died within 3 years. Global and recurrence-free survival among patients who met and patients who exceeded the Milan criteria was not significantly different, suggesting an expansion of the Milan criteria to include potential recipients who were previously excluded. Obtaining histologic differentiation and identifying vascular invasion will provide a more worthwhile contribution to LT decision making. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Medical decision making and risky choices: psychological and medicolegal consequences of HIV and HCV contamination of blood products

    Directory of Open Access Journals (Sweden)

    Riva S

    2017-08-01

    Full Text Available S Riva,1 S Del Sordo,2,3 U Genovese,1,3 G Pravettoni1 1Department of Oncology and Hemato-oncology, University of Milan, Italy; 2FOLSATEC (Foundations & Ethics of the Life Sciences PhD School, University of Milan, Milan, Italy; 3Healthcare Accountability Lab, University of Milan, Milan, Italy Aims: The overall goal of this article is to make a scientific comment about the psycho-social consequences of hemophilia patients affected by human immunodeficiency virus (HIV and/or hepatitis C virus (HCV and to point out the related medicolegal issues. Methods: This commentary takes into account some published evidences about the current scenario of hemophilia patients infected by HIV and/or HCV who received contaminated blood products in the late 1970s through 1985. Results: Several psychological and medicolegal consequences are related with HIV and HCV contamination of blood products. A multidisciplinary approach is needed to treat all the difficulties experienced by these patients and to ensure good clinical decisions in medical practice. Conclusion: The literature on the psychosocial functioning of hemophilia patients with human HIV and HCV infection offers a number of implications, including medicolegal issues, that can be discussed for guaranteeing a good level of care and safeguard of this group of patients. Keywords: hemophilia, viral contaminated blood products, monetary compensation, medico-legal issues, medical decision making

  2. Complementary use of high time resolution particulate sampling and PIXE analysis in the study of a severe pollution episode

    International Nuclear Information System (INIS)

    Braga Marcazzan, G.M.; Cavicchioli, C.; Redaelli, P.; Lucarelli, F.; Ventura, A.; Marchionni, M.

    1993-01-01

    In Milan recurrent episodes of severe and long-lasting pollution occur in winter in peculiar meteo-climatic conditions. During one of these episodes, in which the Municipality of Milan probibited traffic circulation for one day, a streaker total filter particulate sampler was operated for one week at the Brera Tower station, located 25 m above ground level in the centre of Milan. In addition gas pollutants and meteorological parameters were also continuously monitored. PIXE analysis of the particulate matter deposit on Nuclepore filter, sampled in the 18-25 January period, provided hourly concentrations of 21 elements. The analysis of time sequence patterns, daily temporal trends of element concentrations together with SPUR and correlation analysis proved effective for the understanding of pollution buildup mechanisms as well as the short term contribution of different sources. In particular, phenomena related to local meteorology, as fumigation, were evidenced. (orig.)

  3. Favorable Long-term Outcome in Patients Submitted to Liver Transplantation After Downstaging of Hepatocellular Carcinoma According to a Brazilian Selection Protocol.

    Science.gov (United States)

    Massarollo, P C B; Coppini, A Z; Salzedas-Netto, A A; Coelho, F F; Minami, T; Gonzalez, A M

    2016-09-01

    In October 2008, the Brazilian Ministry of Health authorized listing of downstaged hepatocellular carcinoma (HCC) for liver transplantation, according to a standardized protocol. The aim of this study was to compare the outcome of patients submitted to liver transplantation after downstaging of HCC with the results other standard indications in Brazil. We conducted a retrospective analysis of 2,667 adult 1st elective deceased-donor liver transplantations registered at the database of the Transplant Notification Center of the São Paulo State Health Secretariat. These cases are classified into 3 groups: "cirrhosis," including 1,709 patients transplanted because of end-stage liver disease; "Milan-HCC," including 873 HCC patients initially meeting the Milan criteria; and "downstaging" group, including 85 HCC patients submitted to tumor downstaging to the Milan criteria before liver transplantation. One-, 3-, 5-, and 6-year patients survivals were, respectively, 82.7%, 72.0%, 66.1%, and 66.1%, in the "downstaging" group and 76.7%, 68.4%, 63.9%, and 63.5% in the "Milan-HCC" group (P = .483). At the same time intervals, patient survivals were 67.8%, 62.9%, 60.9%, and 60.2% in the "cirrhosis" group. These probabilities were significantly lower than those of both "downstaging" (P = .047) and "Milan-HCC" (P = .001) groups. Patients submitted to liver transplantation after downstaging of HCC, according to a Brazilian selection protocol, present long-term outcomes similar to HCC patients initially within the Milan criteria and better survival than recipients with end-stage liver disease. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Changes in the prevalence of parasitic nematode infections in dogs from animal asylums in Warsaw and sourroundings.

    Science.gov (United States)

    Górski, P; Szyja, A; Baska, P; Kazimierczak, K

    2009-01-01

    The distribution of parasitic nematodes of dogs from three shelters for homeless animals in the Warsaw region (Celestynów and Milanówek near Warsaw, Paluch in Warsaw) was investigated. It was found that since our previous investigations (1993-1995) the prevalence of nematode infections had increased in Celestynów and Milanówek and decreased in the municipal shelter in Warsaw (Paluch). The highest percentage of infected animals was found in Celestynów (as in 1993-1995). What can be the importance of local environmental conditions for the prevalence of nematode infections.

  5. More can be less

    DEFF Research Database (Denmark)

    Thomsen, M.R.

    2001-01-01

    Fremlæggelse af en tese om, at en række værker med vilje har en overflod af referencer - til forfatteren, til historien - for at skjule betydningen af dette. Inddragelse af værker af Svend Åge Madsen, J. P. Jacobsen, Milan Kundera og Jorge Luis Borges.......Fremlæggelse af en tese om, at en række værker med vilje har en overflod af referencer - til forfatteren, til historien - for at skjule betydningen af dette. Inddragelse af værker af Svend Åge Madsen, J. P. Jacobsen, Milan Kundera og Jorge Luis Borges....

  6. The stellar spectroscopy laboratory and curriculum counselling for secondary-school students

    International Nuclear Information System (INIS)

    Cenadelli, D.

    2011-01-01

    The stellar spectroscopy laboratory is the flagship of a wide-ranging work of curriculum counselling fostered by the Physics Department of the Milan University and the high school 'G. Parini' in Milan. In time, valuable results were gained in setting up a new way of collaboration between the high school and university worlds and in spurring secondary-school students to embark in a scientific, and more specifically physical, career. The present work briefly discusses the contents of the laboratory, its didactical value, its role of curriculum counselling and its effectiveness in directing students to take into consideration the physical sciences as a possible university choice.

  7. Turning Time from Enemy into an Ally Using the Pomodoro Technique

    Science.gov (United States)

    Wang, Xiaofeng; Gobbo, Federico; Lane, Michael

    Time is one of the most important factors dominating agile software development processes in distributed settings. Effective time management helps agile teams to plan and monitor the work to be performed, and create and maintain a fast yet sustainable pace. The Pomodoro Technique is one promising time management technique. Its application and adaptation in Sourcesense Milan Team surfaced various benefits, challenges and implications for distributed agile software development. Lessons learnt from the experiences of Sourcesense Milan Team can be useful for other distributed agile teams to turn time from enemy into an ally.

  8. Visiting a Museum Together: How To Share a Visit to a Virtual World.

    Science.gov (United States)

    Paolini, Paolo; Barbieri, Thimoty; Loiudice, Paolo; Alonzo, Francesca; Zanti, Marco; Gaia, G.

    2000-01-01

    Examines different types of virtual visits to museums and explores different paradigms for providing interactive experiences while visiting virtual museums. Describes one example of an experimental environment, WebTalk, which has been used in the MST (Museum of Science and Technology) in Milan, Italy. (LRW)

  9. Investigating L2 Spoken English through the Role Play Learner Corpus

    Science.gov (United States)

    Nava, Andrea; Pedrazzini, Luciana

    2011-01-01

    We describe an exploratory study carried out within the University of Milan, Department of English the aim of which was to analyse features of the spoken English of first-year Modern Languages undergraduates. We compiled a learner corpus, the "Role Play" corpus, which consisted of 69 role-play interactions in English carried out by…

  10. Formalized Combined 2003 European Guidelines on Cardiovascular Disease Prevention and Hypertension

    Czech Academy of Sciences Publication Activity Database

    Peleška, Jan; Anger, Z.; Buchtela, David; Tomečková, Marie; Veselý, Arnošt; Zvárová, Jana

    23 Suppl. 2, - (2005), s. 196 ISSN 0263-6352. [European Meeting on Hypertension /15./. 17.06.2005-21.06.2005, Milan] R&D Projects: GA AV ČR 1ET200300413 Institutional research plan: CEZ:AV0Z10300504 Keywords : European medical guidelines * formalization of combined guidelines Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  11. Slovenský zakladatel ČSR

    Czech Academy of Sciences Publication Activity Database

    Hájková, Dagmara

    2017-01-01

    Roč. 30, 30. 9. (2017), s. 30 ISSN 0862-5921 Grant - others:AV ČR(CZ) StrategieAV21/12 Program:StrategieAV Institutional support: RVO:67985921 Keywords : Milan Rastislav Štefánik Subject RIV: AB - History

  12. Antibiotic Resistance Pattern and Molecular Epidemiology of ...

    African Journals Online (AJOL)

    Data processing and Analysis. Gels images were taken by GEL DOC XR (Bio. Rad Milan, Italy) and analyzed with BioNumerics software Gel Compar II (Applied Maths, Kortrijk,. Belgium). ..... Gehanno JF, Louvel A, Nouvellon M, Caillard JF, Pestel-. Caron M. Aerial dispersal of methicillin-resistant. Staphylococcus aureus in ...

  13. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Synthesis and bio-catalytic activity of isostructural cobalt(III)-phenanthroline complexes · Dhananjay Dey Arnab Basu Roy Anandan Ranjani Loganathan Gayathri Saravanan Chandraleka Dharumadurai Dhanasekaran Mohammad Abdulkader Akbarsha Chung-Yu Shen Hui-Lien Tsai Milan Maji Niranjan Kole Bhaskar ...

  14. Download this PDF file

    African Journals Online (AJOL)

    Fr. Ikenga

    streets of Milan, Italy by CIA agents and then transferred to Egypt where he was allegedly tortured by. Egyptian secret services.45On 9 November 2009, the 23 CIA officers involved in the incident were tried by an Italian court in absentia, convicted of kidnapping and sentenced to terms of imprisonment ranging between five ...

  15. An Average Daily Number of Steps Negatively Correlates with an Average Glycemic Value in Type I Diabetic Patients: Comparison between CGM and Pedometer Records

    Czech Academy of Sciences Publication Activity Database

    Brož, J.; Holubová, A.; Mužík, J.; Oulická, M.; Mužný, M.; Poláček, M.; Fiala, D.; Arsand, E.; Brabec, Marek; Kvapil, M.

    2016-01-01

    Roč. 18, Suppl. 1 (2016), A70-A70 ISSN 1520-9156. [ATTD 2016. International Conference on Advanced Technologies & Treatments for Diabetes /9./. 03.02.2016-06.02.2016, Milan] Institutional support: RVO:67985807 Subject RIV: BB - Applied Statistics, Operational Research

  16. USSR Report, International Affairs, The Working Class and the Contemporary World, Number 6, November-December 1985

    Science.gov (United States)

    1986-07-14

    pensano gli operai. Lavoro, economia e politica negli orientamenti operai agli inizi anni ottanta," Milan, 1984, pp 79-80. 11. See, for example...Cape Verde , and others at various stages of development. Each of them has significant distinctive features of development which demand rigorously

  17. Angiotensin-dependent sympathetic vasoconstriction in SHR: The effect of captopril treatment in young animals

    Czech Academy of Sciences Publication Activity Database

    Kuneš, Jaroslav; Dobešová, Zdenka; Zicha, Josef

    2005-01-01

    Roč. 23, č. S2 (2005), S234-S234 ISSN 0263-6352. [European Meeting on Hypertension /15./. 17.06.2005-21.06.2005, Milan] R&D Projects: GA ČR(CZ) GA305/03/0769; GA MZd(CZ) NR7786 Keywords : angiotensin * sympathetic vasoconstriction * captopril * young animals Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  18. Use of Combination Thermal Therapy and Radiation in Breast-Conserving Treatment of Extensive Intraductal Breast Cancer

    Science.gov (United States)

    1997-07-01

    C,, > < Lo, a)- a)u 0 a, -a), Cu 0 C: C LLE <• :3 L- 000 >> > Mux circuits allow for 96 RF amps to drive 384 transducers. 96 receiver ports are...Staudacher, V et al, eds. il carcinoma della mammella. Milan: Casa Editrice Ambrosiana, 1983. 19. Harris JR, Hellman S: Chemotherapy for breast cancer - a new

  19. Clinical Variability of GLUT1DS

    Directory of Open Access Journals (Sweden)

    Anastasia Martinez-Esteve Melnikova

    2015-02-01

    Full Text Available Investigators from Pavia, Rho, Brescia and Milan, Italy, studied 22 patients diagnosed with GLUT1 deficiency syndrome (GLUT1DS to document clinical or genetic differences between patients with familial SLC2A1 gene mutations (n=11 and those with sporadic mutations (n=11.

  20. Hypertension and other Risk Factors of Atherosclerosis in the Czech Population

    Czech Academy of Sciences Publication Activity Database

    Tomečková, Marie; Grünfeldová, H.; Peleška, Jan; Hanuš, P.; Marušiaková, Miriam

    2007-01-01

    Roč. 25, Suppl. 2 (2007), S 353-S 353 ISSN 0952-1178. [European Meeting on Hypertension /17./. 15.06.2007-19.06.2007, Milan] R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : atherosclerosis * risk factors * hypertension Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  1. Blok vzpomínek na Felixe Vodičku doplňujeme přílohou...

    Czech Academy of Sciences Publication Activity Database

    Janáček, Pavel

    2017-01-01

    Roč. 28, č. 4 (2017), s. 197-198 ISSN 0862-6928 Institutional support: RVO:68378068 Keywords : Vodička, Felix * Králík, Oldřich * Milan Kundera * Czech literary criticism * 1950s * 1960s * 1970s Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  2. Lingua franca in Central Europe after the Disappearance of German

    NARCIS (Netherlands)

    Snel, G.

    2012-01-01

    This chapter discusses a multilingual community of writers and intellectuals who gathered around the idea of a Central European culture in the 1980s, during the last decade of the Cold War. Czesław Miłosz, Danilo Kiš, Milan Kundera, György Konrád and others advocated the idea of a Central European

  3. ORIGINAL ARTICLES A contrast-enhanced ultrasound study of ...

    African Journals Online (AJOL)

    2008-04-21

    Apr 21, 2008 ... The diagnostic methods currently used to distinguish between benign and malignant breast lesions are all invasive and often inconclusive. This may lead to surgery for histological assessment.1 The main objective of this study was to determine the diagnostic accuracy of SonoVue (Bracco spa, Milan).

  4. A contrast-enhanced ultrasound study of benign and malignant ...

    African Journals Online (AJOL)

    Methods. An HDI 5000 Phillips ultrasound scanner with microvascular imaging software and 2.5 ml SonoVue (Bracco spa, Milan) contrast was used to scan 50 consecutive patients (32 malignant and 18 benign, 49 with histologically confirmed breast lesions). Time-intensity curves of the regions of interest (ROI) placed over ...

  5. The Element of Space in Development Planning

    NARCIS (Netherlands)

    L.B.M. Mennes (Loet); J.G. Waardenburg (George); J. Tinbergen (Jan)

    1969-01-01

    textabstractIn Italian: Lo Spazio nei Piani Economici, Franco Angeli Editore, Milan, 1972, 391 p. In Spanish: El Factor Espacio en la Planificación del Desarollo, Series ‘Fondo de Cultura Económica’, Fondo de Cultura Económica, Mexico, 1980, 405 p.

  6. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Synthesis and bio-catalytic activity of isostructural cobalt(III)-phenanthroline complexes. Dhananjay Dey Arnab Basu Roy Anandan Ranjani Loganathan Gayathri Saravanan Chandraleka Dharumadurai Dhanasekaran Mohammad Abdulkader Akbarsha Chung-Yu Shen Hui-Lien Tsai Milan Maji Niranjan Kole Bhaskar ...

  7. Crystal structure and bio-mimicking of Catecholase activity

    Indian Academy of Sciences (India)

    Unprecedented hetero-geometric discrete copper(II) complexes: Crystal structure and bio-mimicking of Catecholase activity. ABHRANIL DE DHANANJAY DEY HARE RAM YADAV MILAN MAJI VINAYAK RANE R M KADAM ANGSHUMAN ROY CHOUDHURY BHASKAR BISWAS. Regular Article Volume 128 Issue 11 ...

  8. 2017-2018 Travel Expense Reports for Dominique Corti, Governor

    International Development Research Centre (IDRC) Digital Library (Canada)

    Lorena Marrero

    Purpose: Board Meetings. Date(s):. 2017-11-19 to 2017-11-24. Destination(s):. Ottawa. Airfare: $6,660.28. Other. Transportation: $38.93. Accommodation: $851.24. Meals and. Incidentals: $309.42. Other: $0.00. Total: $7,859.87. Comments: From residence in Milan, Italy. 2017-2018 Travel Expense Reports for. Dominique ...

  9. 2017-2018 Travel Expense Reports for Dominique Corti, Governor

    International Development Research Centre (IDRC) Digital Library (Canada)

    SD

    Purpose: Board Meetings. Date(s):. 2017-06-17 to 2017-06-22. Destination(s):. Ottawa. Airfare: $7,276.00. Other. Transportation: $83.53. Accommodation: $542.78. Meals and. Incidentals: $155.50. Other: $0.00. Total: $8,057.81. Comments: From residence in Milan, Italy. 2017-2018 Travel Expense Reports for. Dominique ...

  10. 2017-2018 Travel Expense Reports for Dominique Corti, Governor

    International Development Research Centre (IDRC) Digital Library (Canada)

    SD

    07-11. Destination(s):. Kenya, Uganda and Tanzania. Airfare: $5,319.87. Other. Transportation: $82.43. Accommodation: $2,107.26. Meals and. Incidentals: $317.46. Other: $260.82. Total: $8,087.84. Comments: Residence in Milan, Italy.

  11. Nad odkazem Milana Mráze. Rozhovor s Pavlem Baranem

    Czech Academy of Sciences Publication Activity Database

    Boháček, Kryštof; Baran, Pavel

    2011-01-01

    Roč. 3, č. 5 (2011), s. 343-365 ISSN 1803-7860 Institutional research plan: CEZ:AV0Z90090514 Keywords : Milan Mraz * Academic politics * Institute of Philosophy of the Academy of Sciences of the Czech Republic * philosophy and post-totalitarism * science and industrial lobby Subject RIV: AA - Philosophy ; Religion

  12. Disability and Functional Profiles of Patients with Myasthenia Gravis Measured with ICF Classification

    Science.gov (United States)

    Leonardi, Matilde; Raggi, Alberto; Antozzi, Carlo; Confalonieri, Paolo; Maggi, Lorenzo; Cornelio, Ferdinando; Mantegazza, Renato

    2009-01-01

    The objective of this study is to describe functional profiles of patients with myasthenia gravis (MG), and the relationships among symptoms, activities and environmental factors (EF), by using WHO's International Classification of Functioning Disability and Health (ICF). Patients were consecutively enrolled at the Besta Institute of Milan, Italy.…

  13. Disability and Functional Profiles of Patients with Migraine Measured with ICF Classification

    Science.gov (United States)

    Raggi, Alberto

    2010-01-01

    To describe the functional profiles of patients with migraine, and the relationships between symptoms, activities and environmental factors, using WHO's International Classification of Functioning (ICF). Patients were consecutively enrolled at the Besta Institute of Milan. The ICF checklist was administered and two count-based indexes developed:…

  14. Kokk discusses unified foreign service with Czechs / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2010-01-01

    Välisministeeriumi kantsler Marten Kokk kohtus Tšehhi Euroopa asjade asevälisministri Vladimir Galuska ja haldusküsimuste aseministri Milan Sedlacekiga. Kohtumistel räägiti Euroopa Liidu välisteenistuse loomisest, Euroopa Liidu laienemisest ja idapartnerlusest ning Eesti ja Tšehhi vahelistest suhetest

  15. Yttrium-90 radioembolization as a bridge to liver transplantation: a single-institution experience.

    Science.gov (United States)

    Tohme, Samer; Sukato, Daniel; Chen, Hui-Wei; Amesur, Nikhil; Zajko, Albert B; Humar, Abhinav; Geller, David A; Marsh, James W; Tsung, Allan

    2013-11-01

    To evaluate our experience with the use of yttrium-90 ((90)Y) radioembolization in maintaining potential candidacy and, in some instances, downstaging hepatocellular carcinoma (HCC) that does not meet Milan criteria for liver transplantation. A retrospective review of 20 consecutive patients with HCC who were listed to receive a liver transplant and were treated with (90)Y radioembolization as a sole modality for locoregional "bridge" therapy was performed. Demographics, radiographic and pathologic response, survival, and recurrences were examined. Twenty-two (90)Y treatments were performed in 20 patients before transplantation. Median time from first treatment to transplantation was 3.5 months. HCC in 14 patients met the Milan criteria at the time of the first (90)Y treatment, and HCC in six did not. All cases that originally met the Milan criteria remained within the criteria before transplantation, and two of six patients whose disease did not meet the criteria (33%) had their disease successfully downstaged to meet the criteria. Overall, nine patients (45%) had complete or partial radiologic response to (90)Y radioembolization according to modified Response Evaluation Criteria In Solid Tumors. Complete necrosis of tumor with no evidence of viable tumor on pathologic examination was observed in five patients (36%) whose disease met the Milan criteria. Particularly in regions with long wait list times, (90)Y treatment is effective in maintaining tumor size in potential liver transplantation candidates with HCC. In addition, it can also be considered as a downstaging therapy in select patients before transplantation. © SIR, 2013.

  16. MMP-1 polymorphism and its relationship to pathological processes

    Indian Academy of Sciences (India)

    Madhsudhan

    Matrix metalloproteinases (MMPs) are a family of zinc (Zn)-dependent endopeptidases that are collectively capable of cleaving virtually all ..... stromal effectors of human carcinoma progression: therapeutic implications; Matrix Biol. .... Lièvre A, Milet J, Carayol J, Le Corre D, Milan C, Pariente A, Nalet. B, Lafon J, Faivre J, ...

  17. Vzpomínka na Milana Mráze. Rozhovor s Vilémem Heroldem

    Czech Academy of Sciences Publication Activity Database

    Boháček, Kryštof; Herold, Vilém

    2011-01-01

    Roč. 3, č. 5 (2011), s. 331-341 ISSN 1803-7860 Institutional research plan: CEZ:AV0Z90090514 Keywords : Milan Mraz * Classical studies * Aristotle * Academic politics * Institute of Philosophy of the Academy of Sciences of the Czech Republic Subject RIV: AA - Philosophy ; Religion

  18. Morire per un iPhone (Dying for an iPhone), Italian translation

    OpenAIRE

    Chan, Jenny

    2015-01-01

    Ngai Pun, Jenny Chan and Mark Selden. 2015. Morire per un iPhone (Dying for an iPhone). Translated in Italian by Ferruccio Gambino and Giorgio Grappi; edited by Ferruccio Gambino and Devi Sacchetto. Milan: Jaca Books. 269 pages. ISBN: 978-88-16-41246-0

  19. Multifocal manifestation does not affect vascular invasion of hepatocellular carcinoma: implications for patient selection in liver transplantation

    NARCIS (Netherlands)

    Löhe, Florian; Angele, Martin K.; Rentsch, Markus; Graeb, Christian; Gerbes, Alexander; Löhrs, Udo; Beuers, Ulrich; Jauch, Karl-Walter

    2008-01-01

    BACKGROUND AND AIMS: Liver transplantation (OLT) for hepatocellular carcinoma (HCC) improves patient survival when tumor size and number are limited according to the Milan criteria. However, the impact of tumor size vs. the number of lesions for tumor recurrence after OLT is unclear. Microvascular

  20. Intermediate Fragment

    DEFF Research Database (Denmark)

    Kruse Aagaard, Anders

    2015-01-01

    ‘Engaging Through Architecture’ in 2015 by Aarhus School of Architecture as a part of the Ventura Lambrate Milan Design Week, where it was exhibited under the name Concrete. The fundamental pool of techniques and knowledge that set the agenda for the fragment was established before the intentions...

  1. Inequality and rising levels of socio-economic segregation: lessons from a pan-European comparative study

    NARCIS (Netherlands)

    Marcińczak, S.; Musterd, S.; van Ham, M.; Tammaru, T.; Tammaru, T.; Marcińczak, S.; van Ham, M.; Musterd, S.

    2016-01-01

    The Socio-Economic Segregation in European Capital Cities: East Meets West project investigates changing levels of socio-economic segregation in 13 major European cities: Amsterdam, Budapest, Vienna, Stockholm, Oslo, London, Vilnius, Tallinn, Prague, Madrid, Milan, Athens and Riga. The two main

  2. Don Davide Albertario propagandista antiebraico. L'accusa di omicidio rituale

    Directory of Open Access Journals (Sweden)

    Annalisa Di Fant

    2011-05-01

    Full Text Available The article analyses the leading role played by the priest/journalist Davide Albertario in the catholic antisemite propaganda of the late 19th century. He was director of "L'Osservatore Cattolico", a Milan-based daily paper belonging to the catholic press network controlled by the Vatican, that published many articles against the Jews, notably involving the blood libel.

  3. Teaching the Short Story: A Guide to Using Stories from around the World.

    Science.gov (United States)

    Neumann, Bonnie H., Ed.; McDonnell, Helen M., Ed.

    An innovative and practical resource for teachers looking to move beyond English and American works, this book explores 175 highly teachable short stories from nearly 50 countries, highlighting the work of recognized authors from practically every continent, authors such as Chinua Achebe, Anita Desai, Nadine Gordimer, Milan Kundera, Isak Dinesen,…

  4. e-University: A Cross-Case Study in Four Italian Universities

    Science.gov (United States)

    Ghislandi, Patrizia; Calidoni, Paolo; Falcinelli, Floriana; Scurati, Cesare

    2008-01-01

    This paper describes the aims, the methods, the stages and the results of the research project "e-University. Information and communication technologies (ICTs) as a factor of change in Italian universities", undertaken between 2003 and 2006 by the Universities of Trento, Perugia and Sassari and the Catholic University of Milan. The…

  5. Separation Aspects of the 99mTc Cyclotron Production

    Czech Academy of Sciences Publication Activity Database

    Lebeda, Ondřej; Ráliš, Jan; Zyuzin, A.; van Lier, E. J.

    2012-01-01

    Roč. 39, P0314 (2012), S412-S412 ISSN 1619-7070. [25th Annual Congress of the European-Association-of-Nucelar Medicine . 27.10.2012-31.10.2012, Milan] Institutional support: RVO:61389005 Keywords : radionuclide production * radiodiagnostic * technecium Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

  6. The unveiling of life: Liturgy and the lure of kitsch | Cilliers | HTS ...

    African Journals Online (AJOL)

    This article probes the classic definition of religious aesthetics as related to the notions of beauty, goodness and truth. The phenomenon of kitsch, understood as simulation (or inversion) of beauty, goodness and truth, is taken cognisance of, especially in the light of contributions by Milan Kundera, Umberto Eco and Jean ...

  7. LIBO - boosting medical cyclotron facilities for cancer therapy Exhibition LEPFest 2000

    CERN Multimedia

    2000-01-01

    Length : Energy boost : From 62 to 200 MeVAccelerating gradient : 10 MeV/metreAccelerating frequency : 3 GHz Collaboration : CERN, INFN and University of Milan, INFN and University of Naples and TERA foundation Prototype test in 2001 : SC cyclotron Catania

  8. Bruno Munari and the invention of modern graphic design in Italy, 1928-1945

    NARCIS (Netherlands)

    Colizzi, Alessandro

    2011-01-01

    This study examines Bruno Munari’s work as a graphic designer from the late 1920s to mid-1940s, with the aim of understanding the emergence and characteristics of the modernist trend in Italian graphic design. Taking shape in Milan, an original ‘design culture’ eclectically brought together two

  9. Short-term effects of particulate air pollution on cardiovascular diseases in eight European cities

    NARCIS (Netherlands)

    Le Tertre, A; Medina, S; Samoli, E; Forsberg, B; Michelozzi, P; Boumghar, A; Vonk, JM; Bellini, A; Atkinson, R; Ayres, JG; Sunyer, J; Schwartz, J; Katsouyanni, K

    2002-01-01

    Study objective: As part of the APHEA project this study examined the association between airborne particles and hospital admissions for cardiac causes (ICD9 390-429) in eight European cities (Barcelona, Birmingham, London, Milan, the Netherlands, Paris, Rome, and Stockholm). All admissions were

  10. Case report

    African Journals Online (AJOL)

    abp

    2012-06-04

    Jun 4, 2012 ... Immunohistochemical staining revealed strong, diffuse positive S-100 protein and staining for the melanoma markers HMB45 and Milan A, was suggestive of malignant melanoma, and omentum?s lesion metastatic. Palliative Chemotherapy with. Interferon alpha 2b (IFN∞2b) was begun by the oncology ...

  11. Ways of Seeing Data: Towards a Critical Literacy for Data Visualizations as Research Objects and Research Devices

    NARCIS (Netherlands)

    Gray, J.; Bounegru, L.; Milan, S.; Ciuccarelli, P.; Kubitschko, S.; Kaun, A.

    2016-01-01

    Gray, Bounegru, Milan and Ciuccarelli contribute towards a critical literacy for data visualizations as research objects and devices. The chapter argues for methodological reflexivity around the use of data visualizations in research as both instruments and objects of study. The authors develop a

  12. Bonding Geometry and Bonding Character of Thiocyanate Adsorbed on A Ag(100)

    Science.gov (United States)

    1991-03-07

    Research Center. This work has been supported, in part, by the office of Naval Research. - 17- Permanent address: Dipartimento di Chimica Inorganica e...Metallorganica, University of Milan, via Venezian 2t, 20133 Milano, Italy +Permanent address: Departament Quimica Fisica, Facultat de Quimica

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 36; Issue 1. P1 peptidase – a mysterious protein of family Potyviridae. Jana Rohožková Milan Navrátil ... The coding region for P1 peptidase is located at the very beginning of the viral genome of the family Potyviridae. Until recently P1 was thought of as serine peptidase with ...

  14. Hydroelectric power plants may influence profit of company

    International Nuclear Information System (INIS)

    Regula, E.

    2006-01-01

    In this interview with divisional manager of the Division of control of operation of hydroelectric power plants of the Slovenske elektrarne, a.s. Mr. Milan Chudy is published. The effectiveness and its optimisation in hydroelectric power plants of the Slovenske elektrarne, a.s. are discussed

  15. Muusika DVD-d / Mart Normet

    Index Scriptorium Estoniae

    Normet, Mart, 1979-

    2006-01-01

    Uutest DVD-dest U2 "ZooTV: Live From Sydney", Cool D "Legaalselt eetris", Pink Floyd "Pulse", Depeche Mode "Touring The Angel: Live In Milan", Rammstein "Völkerball", Metsatöll "Lahinguväljal näeme, raisk"

  16. ·The clinical and biochemical effects of two combination oral ...

    African Journals Online (AJOL)

    1991-04-06

    Apr 6, 1991 ... a commercial kit (Boehringer-Mannheim CHOD-PAP High. Performance kit) and triglyceride was similarly determined. (Clinical Colorimetric Enzymatic Method, Carlo Erba, Milan). HDL-C was measured after precipitation of the low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL).

  17. Training with O (Observing) and T (Treatment) Teams in Live Supervision: Reflections in the Looking Glass.

    Science.gov (United States)

    Roberts, Janine; And Others

    1989-01-01

    Describes process that six counselor trainees and two supervisors used with treatment and observation teams to examine their own coevolution as a therapeutic system using the Milan model of family therapy and Ericksonian hypnotherapy. Concludes with a discussion of advantages and pitfalls of this type of dual supervision. (Author/ABL)

  18. Euclid's Fifth Postulate

    Indian Academy of Sciences (India)

    Srimath

    at a Jesuit college in Milan, published a two volume work entitled. Euclid free of every flaw “Euclidus Vindicatus”. ... independent of the remaining postulates and that all attempts at proving it using the other four were .... This is true independent of the fifth postulate and depends only on the idea of a larger angle. If ∠BCD ...

  19. Unprecedented hetero-geometric discrete copper (II) complexes ...

    Indian Academy of Sciences (India)

    Unprecedented hetero-geometric discrete copper(II) complexes: Crystal structure and bio-mimicking of Catecholase activity. ABHRANIL DE DHANANJAY DEY HARE RAM YADAV MILAN MAJI VINAYAK RANE R M KADAM ANGSHUMAN ROY CHOUDHURY BHASKAR BISWAS. Regular Article Volume 128 Issue 11 ...

  20. Bilge dump detection from SAR imagery using local binary patterns

    CSIR Research Space (South Africa)

    Mdakane, LW

    2015-07-01

    Full Text Available 2015: Remote Sensing: Understanding the Earth for a Safer World, Milan, Italy, 26-31 July 2015 Bilge dump detection from SAR imagery using local binary patterns yz L.W. Mdakane,yz W. Kleynhans,yz C.P. Schwegmann yDepartment of Electrical...

  1. Proper comparison among methods using a confusion matrix

    CSIR Research Space (South Africa)

    Salmon, BP

    2015-07-01

    Full Text Available -1 IGARSS 2015, Milan, Italy, 26-31 July 2015 Proper comparison among methods using a confusion matrix 1,2 B.P. Salmon, 2,3 W. Kleynhans, 2,3 C.P. Schwegmann and 1J.C. Olivier 1School of Engineering and ICT, University of Tasmania, Australia 2...

  2. L'altro 'Fuori' E L'altro 'Dentro' Nel Cinema Italiano Contemporaneo ...

    African Journals Online (AJOL)

    In these three films, immigrants are represented respectively together with a bunch of young living in the outskirt of Milan, a young man migrated from Abruzzo to Rome and a homosexual girl in the North-East; both, the immigrant and the Italian, share a sense of strangeness and otherness to the social reality they live in and ...

  3. Impact of Arterial Hypertension on Short-Therm Mortality and in Hospital Complications of Patiens with Acute Myocardial Infarction:

    Czech Academy of Sciences Publication Activity Database

    Monhart, Z.; Faltus, Václav; Grünfeldová, H.; Ryšavá, D.; Velimský, T.; Ballek, J.; Hubač, J.; Janský, P.

    2007-01-01

    Roč. 25, Suppl. 2 (2007), S 360-S361 ISSN 0952-1178. [European Meeting on Hypertension /17./. 15.06.2007-19.06.2007, Milan] Institutional research plan: CEZ:AV0Z10300504 Keywords : arterial hypertension * myocardial infarction * short-term mortality

  4. 10 Détermination des radionucléides dans le repas. Application aux ...

    African Journals Online (AJOL)

    ASIMANANA

    Paris), R. ESNAUL (Milan), C. LANCE (Barcelone) – Physiologie Végétales - 1 nutrition 1993. [5] - TAYED Ameziane EL Hassani, ETIENNE Persoons – Base physiologique et agronomiques de la production Végétales – Agronomie moderne, ...

  5. Verification of the capacity of Malpensa Airport: Final report

    OpenAIRE

    Air Transport Group

    2000-01-01

    The purpose of this study is twofold. First, to assess the capacity of Malpensa airport taking into account the impact of environmental measures introduced by the Italian Government Environmental Decree of 13th December 1999. Second, to assess the impact of projected traffic growth in the Milan airport system. European Commission Directorate General Energy and Transport, Directorate F: Air Transport

  6. Characterisation of equine macrophage-derived chemokine and its expression in the skin of horses with recurrent urticaria

    Czech Academy of Sciences Publication Activity Database

    Janda, Jozef; Roosje, P.; Marti, E.

    2013-01-01

    Roč. 68, S1 (2013), s. 341-341 ISSN 0105-4538. [World Allergy and Asthma Congress of the European Academy of Allergy and Clinical Immunology and World Allergy Organization. 22.07.2013-26.07.2013, Milan] Institutional support: RVO:67985904 Keywords : recurrent urticaria Subject RIV: EC - Immunology

  7. A Corpus-Based Stylistic Analysis of "Body-Soul" and "Heaviness-Lightness" Metaphors in Kundera's Novel "The Unbearable Lightness of Being"

    Science.gov (United States)

    Hussein, Khalid Shakir; Ameer, May Ali Abdul

    2015-01-01

    This paper represents an attempt to conduct a corpus-based stylistic analysis of two conceptual metaphors in "The Unbearable Lightness of Being," which is a novel written by Milan Kundera. "Soul-body" and "lightness-heaviness" metaphors are foregrounded as being central themes all through the novel. The way such…

  8. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 837-846. Weighted Moore–Penrose generalized matrix inverse: MySQL vs. Cassandra database storage system · DANIJELA MILOSEVIC SELVER PEPIC MUZAFER SARACEVIC MILAN TASIC · More Details Abstract Fulltext PDF. The research in this paper refers to two areas: programming and data storage (data base) ...

  9. La mafia ai tempi di Expo

    Directory of Open Access Journals (Sweden)

    Il Comitato di esperti antimafia del Comune di Milano

    2016-11-01

    Full Text Available La sezione “Il documento” propone due capitoli della Relazione conclusiva redatta dal “Comitato di esperti per lo studio e la promozione di attività finalizzate al contrasto dei fenomeni di stampo mafioso e della criminalità organizzata sul territorio milanese, anche in vista della manifestazione Expo Milano 2015”, consegnata il 28 ottobre 2016 all’ex Sindaco di Milano Giuliano Pisapia e all’attuale Sindaco Giuseppe Sala. Gli estratti qui proposti riguardano le infiltrazioni mafiose in Expo e la presenza mafiosa a Milano.  Parole chiave: Comitato di esperti; Expo 2015; Milano; ‘ndrangheta; appalti The section ‘The Document” offers two chapters of the last report issued by the Antimafia Committee of the City Council of Milan (Comitato di esperti per lo studio e la promozione di attività finalizzate al contrasto dei fenomeni di stampo mafioso e della criminalità organizzata sul territorio milanese, anche in vista della manifestazione Expo Milano 2015, and presented on the 28th October 2016 to the former Mayor of Milan, Giuliano Pisapia, and to the actual Mayor Giuseppe Sala.  The excerpts here proposed regard the problems faced by the Committee in the years which have led up to Expo 2015 and the new scenarios of the presence of the Mafia in the area of Milan.  Keywords: Committee of experts; Expo 2015; Milan; ‘ndrangheta; public procurements

  10. Ja lahkuda polnud kerge : pisteline essee reetmisest / Tõnu Õnnepalu

    Index Scriptorium Estoniae

    Õnnepalu, Tõnu

    2006-01-01

    Ka Milan Kundera romaanist "Olemise talumatu kergus", Louis-Ferdinand Céline'ist (1894-1961), Pierre Drieu La Rochelle'i (1893-1945) Teise maailmasõja ajal kirjutatud päevikutest ja Jean Genet'st (1910-1986). Ilmunud ka: Vikerkaar nr. 9, 1992

  11. Unusta, säilita, mäleta : kunstnikud materialiseerivad mälu / Laura Põld

    Index Scriptorium Estoniae

    Põld, Laura, 1984-

    2015-01-01

    Rahvusvaheline näitus "Tracing the Memory" Vaal galeriis 17. detsembrist 2014 kuni 17. jaanuarini 2015, kuraatorid Annika Toots ja Slavomira Ondrušová. Eksponeeriti Daniela Krajčová, Jan Nálevka, Katarina Poliačiková, Laura Tootsi ja Milan Vagač'i installatsioone. Kunstnike eluloolisi andmeid

  12. Bibliography on HIV/AIDS in Ethiopia and Ethiopians in the Diaspora

    African Journals Online (AJOL)

    Yemane Berhane

    Other references dealt with the epidemic's psychosocial and economic impacts on people living with HIV/AIDS or their families (e.g., refs. #5, #10, #20). This is an encouraging ... anti-retroviral therapy in the country, the biomedical and psychosocial ...... Milan J, Jr., Robinettte J, Stratten K, Mengistu G, Rigby H. Establishing a ...

  13. Evaluation of 177Lu-nimotuzumab for Targeted Radioimmunotherapy of EGFR Expressing Tumors

    Czech Academy of Sciences Publication Activity Database

    Beckford, Denis R.; Balogh, L.; Postenyi, Z.; Mathe, D.; Eigner, Sebastian; Eigner-Henke, Kateřina; Montana, R. L.; Melichar, František

    2012-01-01

    Roč. 39, P0089 (2012), S327-S327 ISSN 1619-7070. [25th Annual Congress of the European-Association-of-Nucelar Medicine. 27.10.2012-31.10.2012, Milan] Institutional support: RVO:61389005 Keywords : radiotherapy * tumor treatment Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

  14. Navigators for medicine: evolution of online point-of-care evidence-based services

    OpenAIRE

    2010-01-01

    Abstract n/a : Moja, Lorenzo, merged with this user on 09-Mar-2010 by Gaston, Thomas (Moja, Lorenzo) (Moja, Lorenzo) Mario Negri Institute for Pharmacological Research, Italian Cochrane Centre - Milan - ITALY (Moja, Lorenzo) ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY ITALY...

  15. Unpublished Texts: Poesie | Valabrega | Italian Studies in Southern ...

    African Journals Online (AJOL)

    Adriana Valabrega was born in Turin, Italy in 1957. She obtained a degree in Theoretical Philosophy at the University of Turin with a thesis on the Philosophy of dialogue by Martin Buber. She lives in Milan and currently teaches Philosophy and History at the High School “Liceo classico Beccaria”. Some poems have ...

  16. Nedožité devadesátiny Milana Otáhala

    Czech Academy of Sciences Publication Activity Database

    Tůma, Oldřich

    2017-01-01

    Roč. 24, 1/2 (2017), s. 247-251 ISSN 1210-7050 Institutional support: RVO:68378114 Keywords : Milan Otáhal * obituary * historiography Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  17. The Toxicology, Environmental Fate, and Human Risk of Herbicide Orange and Its Associated Dioxin

    Science.gov (United States)

    1978-10-01

    J i 4.) 0V- 1 6. A simultaneous psoriasis or a systemic eczema in the previous case history, or a pregnancy, did not make any difference and had no...program. Medical - epidemio- logical commission. Milan, Italy, August 27, 1976. Mim. 10 p. 38. Firestone, D. 1977. The 2,3,7,8-tetrachlorodibenzo- para

  18. Feeling Insecure in Large Housing Estates: Tackling Unsicherheit in the Risk Society

    NARCIS (Netherlands)

    Aalbers, M.B.; Rancati, S.

    2008-01-01

    The aim of this paper is to analyse Zygmunt Bauman’s three-part concept of Sicherheit (safety, certainty and security) in the specifi c context of large housing estates in Amsterdam (the Netherlands) and Milan (Italy). The effi cacy of the different actions and policies, which seek to tackle

  19. A Fruitful Exchange/Conflict: Engineers and Mathematicians in Early Modern Italy

    Science.gov (United States)

    Maffioli, Cesare S.

    2013-01-01

    Exchanges of learning and controversies between engineers and mathematicians were important factors in the development of early modern science. This theme is discussed by focusing, first, on architectural and mathematical dynamism in mid 16th-century Milan. While some engineers-architects referred to Euclid and Vitruvius for improving their…

  20. Teachers' Ideas about Health: Implications for Health Promotion at School

    Science.gov (United States)

    Miglioretti, Massimo; Velasco, Veronica; Celata, Corrado; Vecchio, Luca

    2013-01-01

    Objectives: The study explores the relationships among teachers' health representations, their ideas about health promotion, their working conditions and their involvement in health-promotion activities at school. Methods: A questionnaire was administered to 107 teachers in 86 schools in Milan (Italy). The questionnaire was structured in four…

  1. Synthesis and Quality Control of [18F]fluoropropanoyl-Gluc-Lys-TOCA for Somatostatine Receptors Imaging

    Czech Academy of Sciences Publication Activity Database

    Procházka, Libor; Kropáček, Martin; Bašta, Jiří; Melichar, František

    2012-01-01

    Roč. 39, P0310 (2012), S411-S411 ISSN 1619-7070. [25th Annual Congress of the European-Association-of-Nucelar Medicine. 27.10.2012-31.10.2012, Milan] Institutional support: RVO:61389005 Keywords : radiodiagnostic Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

  2. 5-grass pollen tablets achieve disease control in patients with seasonal allergic rhinitis unresponsive to drugs: a real-life study

    Directory of Open Access Journals (Sweden)

    Pastorello EA

    2013-12-01

    Full Text Available Elide Anna Pastorello,1 Laura Losappio,1 Stefania Milani,2 Giuseppina Manzotti,3 Valentina Fanelli,4 Valerio Pravettoni,5 Fabio Agostinis,6 Alberto Flores D’Arcais,7 Ilaria Dell'Albani,8 Paola Puccinelli,9 Cristoforo Incorvaia,10 Franco Frati81Allergy and Immunology Department, Niguarda Hospital, Milan, 2Allergy Department, San Marco General Hospital, Bergamo, 3Allergy Department, Treviglio Hospital, Bergamo, 4Allergy Department, Italian Institute for Auxology, Milan, 5Clinical Allergy and Immunology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 6Department of Pediatrics, Riuniti Hospital, Bergamo, 7Department of Pediatrics, Legnano Hospital, Milan, 8Medical and Scientific Department, Stallergenes Italy, Milan, 9Regulatory Department, Stallergenes Italy, Milan, 10Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, ItalyBackground: An important subpopulation in allergic rhinitis is represented by patients with severe form of disease that is not responsive to drug treatment. It has been reported that grass pollen subcutaneous immunotherapy is effective in drug-resistant patients. In a real-life study, we evaluated the efficacy of 5-grass pollen tablets in patients with grass pollen-induced allergic rhinitis not responsive to drug therapy.Methods: We carried out this multicenter observational study in adults and adolescents with grass-induced allergic rhinitis not responsive to drug therapy who were treated for a year with 5-grass pollen tablets. Clinical data collected before and after sublingual immunotherapy (SLIT included Allergic Rhinitis and its Impact on Asthma (ARIA classification of allergic rhinitis, response to therapy, and patient satisfaction.Results: Forty-seven patients entered the study. By ARIA classification, three patients had moderate to severe intermittent allergic rhinitis, ten had mild persistent allergic rhinitis, and 34 had moderate to severe persistent allergic rhinitis. There were no cases

  3. Age-specific probability of childbirth. Smoothing via bayesian nonparametric mixture of rounded kernels

    Directory of Open Access Journals (Sweden)

    Antonio Canale

    2015-03-01

    Full Text Available The municipality of Milan is one of the most important areas in Italy being the center of many economic activities and the destination of strong national and international immigration. In this context, policy makers are interested in understanding socio-demographical and economical differences among the different urban areas. In this paper we concentrate in estimating differences in fertility among the nine areas of Milan. The knowledge of age-specific fertility indicators, indeed, is extremely useful in order to decide where to build a new nursery-school, where to increase obstetrics departments in hospitals, or which kind of services can be offered to families.To estimate the age-specific probabilities of child-births in the municipality of Milan, we use open-data on the births residents in Milan in 2011. It has recently been observed that the patterns of fertility of developed countries show a deviation from the classic right-skewed shape due to the fact that women tend to have children later. Also, when a large component of immigrants is present, the age-specific fertility rate exhibits an almost bimodal shape, the curve shows a little hump between 20 and 25 years of the woman, presumably due to the presence of subpopulations. To deal with this phenomena and to compare fertility between the nine urban areas of the municipality of Milan, we apply a Bayesian nonparametric  mixture model which can account for skewness and multimodality and we estimate the age-specific probability of childbirth.

  4. Validation of the AFP model as a predictor of HCC recurrence in patients with viral hepatitis-related cirrhosis who had received a liver transplant for HCC.

    Science.gov (United States)

    Notarpaolo, Andrea; Layese, Richard; Magistri, Paolo; Gambato, Maria; Colledan, Michele; Magini, Giulia; Miglioresi, Lucia; Vitale, Alessandro; Vennarecci, Giovanni; Ambrosio, Cecilia D; Burra, Patrizia; Di Benedetto, Fabrizio; Fagiuoli, Stefano; Colasanti, Marco; Maria Ettorre, Giuseppe; Andreoli, Arnoldo; Cillo, Umberto; Laurent, Alexis; Katsahian, Sandrine; Audureau, Etienne; Roudot-Thoraval, Françoise; Duvoux, Christophe

    2017-03-01

    The AFP model was shown to be superior to the Milan criteria for predicting hepatocellular carcinoma (HCC) recurrence after liver transplantation in a French population. Our aim was to test the AFP model in a non-French, post-hepatitic cirrhosis-based population of HCC candidates. 574 patients transplanted for HCC in four Italian centers were studied. AFP score was assessed at the last evaluation before liver transplantation (LT). Probabilities of recurrence and survival were estimated by the log-rank test or competing risk analysis and compared according to the AFP model. 24.7% patients were beyond Milan criteria. HCC complicated hepatitis C virus (HCV) and hepatitis B virus (HBV) cirrhosis in 58.7% and 24% of the cases, respectively. Five-year probabilities of recurrence differed according to AFP score ⩽2 vs. >2 in the whole population (13.2±1.8% vs. 49.8±8.7%, p2 were 71.7±2.2% vs. 42.2±8.3% (pHCC candidates at low risk of recurrence, otherwise excluded by Milan criteria in a population with a predominance of post-hepatitic-related HCC. The AFP score can be proposed for selection of HCC candidates in programs with a high proportion of viral/HCV-related cirrhosis. Selection criteria for liver transplantation of patients affected with hepatocellular carcinoma (HCC) are based on the Milan criteria, which have been shown to be too restrictive, precluding access to liver transplantation for some patients who might be cured by this operation. Recently, a French group of researchers developed a new selection model called the AFP model, or AFP score, allowing some patients with HCC not meeting Milan criteria to be transplanted with excellent results. In the present work, the AFP score was tested in a population of non-French patients transplanted for HCC occurring mainly on post-hepatitic (HCV or HBV) cirrhosis. The results confirm that in this specific population, as in the original French population of patients, the AFP model better selects patients with HCC

  5. Modern Milano. A survey about transformation of architectural and urban heritage

    Directory of Open Access Journals (Sweden)

    Giovanna D’Amia

    2009-12-01

    Full Text Available The XX Century Milan estate of buildings records the renovation of the culture and the predominance of the Rationalism between the World Wars and the Second postwar. Nevertheless, it is still unknown and poorly documented and it has often suffered radical transformations. Giovanna D’Amia and Luca Tamini formulated an hypothesis of an observatory of the Modern Milan as an interdisciplinary research to deeply know and valorise this estate of buildings, to survey their conditions and to propose guidelines for future interventions. An archive of data and graphic documents of 45 selected buildings has been created by Giovanna D’Amia Course of Contemporary History of Architecture (year 2008/2009 in order to verify the fairness of this approach. Nowadays it is possible to drew up a first balance of the research.

  6. Il sistema rurale. una sfida per la progettazione tra salvaguardia, sostenibilità e governo delle trasformazioni Milano, ottobre 2004

    Directory of Open Access Journals (Sweden)

    Paola Marzorati

    2015-11-01

    Full Text Available Lombardy Region with University Politecnic of Milan organized an international conference “The rural system. A challenge for planning between protection, sustainability and changes' management”, in Milan at 13th-14th October 2004. This meeting's efforts will be addressed in verifying if and how the values of multi-functionality practice can be extended, in the short period, to most part of the rural land. In order to obtain this goal the meeting will focus on recognizing the characters of agricultural land, deepening ecological, socio-economical functions and preserving rural landscape ones as part of a greater and more comprehensive planning process based on sustainable design and on a "good policy" approach. This items and issues will be focused exploring some Italian and international best-practices. 

  7. The Castilian Translations of Quintus Curtius in their Manuscript and Cultural Context

    DEFF Research Database (Denmark)

    Rodríguez Porto, Rosa María; Pascual-Argente, Clara

    2018-01-01

    In 1438, Milanese humanist Pier Candido Decembrio finished the vernacular translation of Quintus Curtius’s Historiae Alexandre Magni, made at the request of his patron, Duke Filippo Maria Visconti of Milan, and accompanied it with a work of his own, the Comparatione di Cesare et d’Alexandro. Dece......In 1438, Milanese humanist Pier Candido Decembrio finished the vernacular translation of Quintus Curtius’s Historiae Alexandre Magni, made at the request of his patron, Duke Filippo Maria Visconti of Milan, and accompanied it with a work of his own, the Comparatione di Cesare et d...... Castilian version by Aragonese nobleman Alfonso de Liñán; and a Catalan translation printed in 1481. These versions have yet to receive the sustained critical attention they deserve.   In this article, we will argue that the Iberian translations of Decembrio’s Alexandrine works are critical to our...

  8. Harvesting Collective Trend Observations from Large Scale Study Trips

    DEFF Research Database (Denmark)

    Eriksen, Kaare; Ovesen, Nis

    2014-01-01

    To enhance industrial design students’ decoding and understanding of the technological possibilities and the diversity of needs and preferences in different cultures it is not unusual to arrange study trips where such students acquire a broader view to strengthen their professional skills and app...... numbers of students to the annual Milan Design Week and the Milan fair ‘I Saloni’ in Italy. The present paper describes and evaluates the method, the theory behind it, the practical execution of the trend registration, the results from the activities and future perspectives....... and approach, hence linking the design education and the design culture of the surrounding world. To improve the professional learning it is useful, though, to facilitate and organize the trips in a way that involves systematic data collection and reporting. This paper presents a method for facilitating study...

  9. Le carte del monastero di S. Maria di Chiaravalle milanese. Additiones documentarie (secolo XII

    Directory of Open Access Journals (Sweden)

    Maria Cristina Piva

    2013-01-01

    Full Text Available Founded in 1135 in the immediate outskirts of Milan, Cistercian monastery of S. Maria di Chiaravalle was one of the most important ecclesiastical institutions in Lombardy. Since its foundation, it has played a prominent role in the political, religious, social and economic life of the city. In the Middle Ages the abbey distinguished itself with intensive production and preservation of documents, exemplified nowadays by the several hundreds of charterse preserved in the Archivio di Stato of Milan. This research aims to complete the organic reconstruction work, recently carried out by Anna Maria Rapetti and Ada Grossi regarding the XII century tabularium of Chiaravalle, with the critical edition of 28 unreleased documents dated between 1106 and 1164. In the introduction, in addition to the presentation of the documents, a paragraph will outline the historiographical balance of the studies conducted so far on the abbey.

  10. Peritoneal Recurrence of Initially Controlled Hepatocellular Carcinoma after Living Donor Liver Transplantation

    Directory of Open Access Journals (Sweden)

    Nariman Sadykov

    2015-01-01

    Full Text Available It is well known that the presence of end-stage liver disease increases the risk of developing hepatocellular carcinoma (HCC. Liver transplantation (LT for patients within the Milan criteria has become a standard treatment for HCC in most developed centers worldwide. However, a major cause of death in cirrhotic patients with HCC after transplantation is tumor recurrence, including peritoneal recurrences, which develops rarely but presents a significant problem with regard to their management. Our experience includes two cases with HCC within the Milan criteria of peritoneal recurrences after living donor LT. Both patients had interventions for HCC in their medical history before LT, and we propose that these might have been a possible cause of the HCC peritoneal recurrence.

  11. Simulation Study of Discharging PCM Ceiling Panels through Night - time Radiative Cooling

    DEFF Research Database (Denmark)

    Bourdakis, Eleftherios; Kazanci, Ongun Berk; Grossule, F.

    2016-01-01

    demand. In the present simulation study, the coupling of nighttime radiative cooling with PCM for cooling an office room was investigated. For cooling water through nighttime radiative cooling two types of solar panels were utilized, an unglazed solar collector and photovoltaic/thermal (PV/T) panels...... provided by the PV/T panels was 43 W/m2 for Copenhagen, while for Milan and Athens it was 36 W/m2 and 34 W/m2, respectively. The cooling power of the unglazed solar collector was negligible. Finally, the total electricity produced in Copenhagen for the simulated period was 371 kWh, while for Milan...... and increase use of renewable energy sources. The aim is that by 2020 all new buildings should be nearly zero-energy buildings. A solution that could contribute to this is the combination of photovoltaic panels for the production of electricity and phase change material (PCM) for the reduction of peak cooling...

  12. Study of sulphation of Candoglia marble by means of micro X-ray diffraction experiments

    Science.gov (United States)

    Pedrazzani, R.; Alessandri, I.; Bontempi, E.; Cappitelli, F.; Cianci, M.; Pantos, E.; Toniolo, L.; Depero, L. E.

    2006-06-01

    This research is aimed at assessing the particular kind of damage caused by the interaction between atmospheric pollution and the marble surface of a magnificent late gothic church, Milan Cathedral, restored in the early 1970s. On the basis of visual inspections and diagnostic investigations the facade appears to be seriously damaged by surface erosion and thick black crusts; biological crusts, micro-fractures and detachments are widely present. This paper reports on SR-μXRD data collected at the Synchrotron Radiation Source (SRS), Daresbury Laboratory, and at the European Synchrotron Radiation Source (ESRF) from selected samples, covered with black crusts, originating from the Milan Cathedral facade. Mineralogical maps of the deterioration layers have been recorded by two spatial resolutions (5-100 μm), from the bulk of the stone material to the outer layer of the black surface. These maps help in elucidating the mechanism of formation of the black crusts.

  13. Effect of indacaterol on lung deflation improves cardiac performance in hyperinflated COPD patients: an interventional, randomized, double-blind clinical trial

    Directory of Open Access Journals (Sweden)

    Santus P

    2015-09-01

    Full Text Available Pierachille Santus,1,2 Dejan Radovanovic,1,2 Silvia Di Marco,3 Vincenzo Valenti,4,5 Rita Raccanelli,1,2 Francesco Blasi,6,7 Stefano Centanni,8,9 Maurizio Bussotti31Department of Health Sciences, University of Milan, 2Pulmonary Rehabilitation Unit, Fondazione Salvatore Maugeri Scientific Institute of Milan-IRCCS, 3Cardiological Rehabilitation Unit, Fondazione Salvatore Maugeri Rehabilitation Institute of Milan-IRCCS, 4Department of Biomedical Sciences for Health, University of Milan, 5Respiratory Unit, Policlinico San Donato-IRCCS, San Donato Milanese, 6Department of Pathophysiology and Transplantation, University of Milan, 7IRCCS Fondazione Ospedale Maggiore Policlinico Cà Granda Milan, 8Department of Health Sciences, University of Milan, 9Respiratory Unit, Ospedale San Paolo, Milan, ItalyBackground: COPD is often associated with cardiovascular comorbidity. Treatment guidelines recommend therapy with bronchodilators as first choice. We investigated the acute effect of single-dose indacaterol on lung hyperinflation in COPD subjects, for the first time evaluating the potential effects on right heart performance.Methods: In this Phase IV, randomized, interventional, double-blind, crossover clinical study, we recruited 40 patients (50–85 years of age with stable COPD. Patients were treated with 150 µg indacaterol or placebo and after 60 minutes (T60 and 180 minutes (T180 the following tests were performed: trans-thoracic echocardiography (TTE, plethysmography, diffusing capacity of the lung for carbon monoxide, saturation of peripheral oxygen, and visual analog scale dyspnea score. Patients underwent a crossover re-challenge after a further 72 hours of pharmacological washout. All TTE measurements were conducted blindly by the same operator and further interpreted by two different blinded operators. Consensus decisions were taken on every value and parameter. The primary outcome was the effect of the reduction of residual volume and functional

  14. LCA Comparison of waste incineration in Denmark and Italy

    DEFF Research Database (Denmark)

    Turconi, Roberto; Butera, Stefania; Boldrin, Alessio

    2011-01-01

    Every year around 50 millions Mg solid waste are incinerated in Europe. Large differences exist in different regions, mainly regarding energy recovery, flue gas treatment and management of solid residues. This paper aims to identify and quantify those differences, providing a Life Cycle Assessment...... of two incinerator systems that are representative of conditions in Northern and Southern Europe. The two case studies are Aarhus (Denmark) and Milan (Italy). The results show that waste incineration appears more environmentally friendly in the Danish case than in the Italian one, due to the higher...... energy recovery and to local conditions, e.g. substitution of electricity and heat in the area. Focusing on the incineration process, Milan incinerator performs better than Aarhus, since its upstream impacts (related to the production of chemicals used in flue gas cleaning) are more than compensated...

  15. Boscovich, the Brera Observatory and the Enlightenment

    Science.gov (United States)

    Antonello, Elio

    2015-05-01

    The year 2011 marks the 300th anniversary of the birth of R.G. Boscovich, one of the most remarkable and neglected figures in the history of modern European science. He was a polymath and gave contributions to mathematics, geometry, optics, astronomy, geodesy, engineering, hydraulics, and also to poetry. He was a Jesuit, and he contributed to the foundation of the Brera Observatory in Milan in 1764-1765. The Milanese Enlightenment flourished in the same period, when important reforms were introduced, that allowed progress in economy, education, science, arts and culture. In this short paper we present the life of Boscovich in the context of his activity and of the cultural environment in Milan.

  16. Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports

    Directory of Open Access Journals (Sweden)

    Ughi N

    2016-03-01

    Full Text Available Nicola Ughi, Chiara Crotti, Francesca Ingegnoli Division of Rheumatology, Department of Clinical Sciences and Community Health, Gaetano Pini Institute, The University of Milan, Milan, Italy Abstract: Digital ulcers (DUs are a severe and frequent clinical feature of patients with systemic sclerosis (SSc. The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds. Keywords: oxycodone, naloxone, systemic sclerosis, pain, digital ulcer, scleroderma, analgaesia, wound healing, opioids, calcinosis, UCLA-SCTC GIT 2.0

  17. In the Footsteps of the Lord of Miracles

    DEFF Research Database (Denmark)

    Pærregaard, Karsten

    2008-01-01

    One of South America's most famous Catholic icons is the Lord of Miracles, celebrated annually by more than a million people in Lima. Over the past three decades Peru's fast-growing diaspora in Europe, the US, Japan and Argentina has made the Lord of Miracles the object of a global expatriation. ...... identity as immigrants. It suggests that the globalisation of the Lord of Miracles is part of a strategy Peruvian migrants use to gain access to public spaces in the host country and thus legitimise their presence and claim legal and political rights as immigrants........ Thus migrants in such cities as Madrid, Barcelona, Milan, Genoa, Rome, Milan, Los Angeles, New York, Washington DC, Tokyo, Kyoto and Buenos Aires organise annual processions to bring the Lord of Miracles to the streets and other public places. This article compares the different strategies migrants...

  18. The effect of antioxidants on the nitric oxide balance and prevention of spontaneous hypertension

    Czech Academy of Sciences Publication Activity Database

    Pecháňová, O.; Kojšová, S.; Paulis, L.; Janega, P.; Zicha, Josef; Dobešová, Zdenka; Kuneš, Jaroslav; Šimko, F.; Andriantsitohaina, R.

    2005-01-01

    Roč. 23, č. S2 (2005), S232-S232 ISSN 0263-6352. [European Meeting on Hypertension /15./. 17.06.2005-21.06.2005, Milan] Grant - others:VEGA(SK) 2/3185/24; VEGA(SK) 1/0532/03; APVT(SK) 51-017902; APVT(SK) 51-013802 Keywords : antioxidants * nitric oxide * spontaneous hypertension Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  19. Kvantitativní analýza léčiv v biologických materiálech separačními metodami

    OpenAIRE

    Maláková, Jana

    2012-01-01

    Charles University in Prague, Faculty of Pharmacy in Hradci Králové Department of Pharmaceutical Chemistry and Drug Control Candidate: PharmDr. Jana Maláková Supervisor: Doc. PharmDr. Milan Nobilis, PhD., Associate Professor of Bioorganic Chemistry. Title of Doctoral Thesis: Quantitative measurement of drugs in biological samples using chromatography methods. The thesis deals with the application of instrumental analytical methods to the quantitative measurement of drugs and their metabolites...

  20. Vybrané otázky překonávání majetkové samostatnosti kapitálových společností ve srovnávacím pohledu

    OpenAIRE

    Kostohryz, Milan

    2012-01-01

    Milan Kostohryz Piercing the Corporate Veil - Selected Issues in International Comparison Abstract The main purpose of the thesis is to give recommendation for possible application of the piercing doctrine in the Czech Republic. Secondary purposes are (i) analysis of effects caused by disregarding the principles of limited liability and separate legal personality because of piercing and (ii) detailed description of approaches to the piercing issue in selected legal systems (USA, UK and German...

  1. European Science Notes. Volume 41, Number 7.

    Science.gov (United States)

    1987-07-01

    present. consideration needs to be given to the His intention is to resolve the con- nose shape of the locomotive to minimize troversy which now...prototype locomotive . to eliminate vibration effects. He will When attempting to make measurements verify this by making measurements of the of wall...human mobility in Milan, and researchers in the robotic division of the University of Pisa are employing molecular bionics to develop synthetic skin to

  2. NOTES AND GLEANINGS / NOTE E CURIOSITÀ

    African Journals Online (AJOL)

    User

    songwriters such as Bruno Lauzi, Gino Paoli, Fabrizio De André, and – from. Milan - Giorgio Gaber and Enzo Iannacci ..... definirlo la “lingua di base” di immediata “disponibilità” e fruibilità, la lingua che milioni di italiani usano .... di quegli anni, possono essere: Il pullover / che mi hai dato tu / sai, mia cara, possiede una virtù.

  3. Bruno Munari and the invention of modern graphic design in Italy, 1928-1945

    OpenAIRE

    Colizzi, Alessandro

    2011-01-01

    This study examines Bruno Munari’s work as a graphic designer from the late 1920s to mid-1940s, with the aim of understanding the emergence and characteristics of the modernist trend in Italian graphic design. Taking shape in Milan, an original ‘design culture’ eclectically brought together two quite different strains of Modernity: a local tradition represented by the Futurist avant-garde, and a European tradition associated with Constructivism. Munari (1907–1998) worked simultaneously as pai...

  4. Immunological Prevention of Spontaneous Mammary Carcinoma in Transgenic Mice

    Science.gov (United States)

    2001-08-01

    developed more slowly by transgenic FVB Anatomia Patologica, Ospedale S.S. Annunziata, Via Valignani, 66100 female mice carrying the wild-type proto...coopted (Pezzella et al., 1997). Anatomia Patologica. Ospedale SS. Annunziata, Via Valignani, 66100 Chieti, Italy. Fax: 39 0871 330471. E-mail: musiani...lo Studio e la Cura dei Tumori, Milan, Italy; and Reprints: Piero Musiani, G. d’ Annunzio University of Chieti, Anatomia Department of Experimental

  5. Smoking in Italy in 2015-2016: Prevalence, trends, roll-your-own cigarettes and attitudes towards incoming regulations

    Directory of Open Access Journals (Sweden)

    Alessandra Lugo

    2017-05-01

    The surveys were conducted with the contribution of the Italian Ministry of Health. This work was partially funded by the European Union’s Horizon 2020 Research and Innovation Programme (The TackSHS Project; grant agreement: 681040 and by the Italian Ministry of Health (MADES project, chapter 4100/22. The work of SG and AL was partially supported by the Italian League Against Cancer (Milan. The authors declare that there are no conflicts of interest.

  6. Regeneration Through Hidden Historical Landscape of Lecco. Urban Course Design Process

    OpenAIRE

    Colucci, Angela; Kolmogorova, Anna; Kraja, Benida; Ziyaee, Maryam

    2017-01-01

    The article focus on the role of Historical Urban Heritage in Urban Design through the presentation of the integrated learning  path developed for Urban Design and Urban Design Studio classes of Lecco Campus of Politecnico of Milan (school of Architecture Urban Planning Construction Engineering, master degree in Building and Architectural Engineering - BAE and Architectural-Engineering– EDA). The first part of paper presents the general learning process characterizing Urban Design course a...

  7. A Critical But Missing Piece: Educating Our Professional Military on the History of Islam

    Science.gov (United States)

    2011-04-01

    House, 2004), xxi 16. Davis, Don’t Know Much about History , xii. 17. Ibid. 18. Milan Vego, “Military History and the Study of Operational Art ,” Joint...Spring 2011 71 A Critical But Missing Piece: Educating Our Professional Military on the History of Islam AdAm Oler If you would understand...anything, observe its beginning and its development.1 —Aristotle Introduction To someone familiar with the history of Ancient Greece, the story will

  8. Mr. Eduard Zeman, Minister of Education, Youth and Sport, Czech Republic

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    Mr Eduard Zeman (third from left), Minister of Education, Youth and Sport, Czech Republic, visiting CERN's permanent exhibition, Microcosm, with (from left to right) Dr Rupert Leitner, ATLAS Tile Calorimetry Project Leader; Mr P. Cink, Ministry of Education, Youth and Sport; Dr Ivan Lehraus, Committee for Collaboration of the Czech Republic with CERN; and H.E. Mr Milan Hovorka, Ambassador, permanent representative of the Czech Republic to the United Nations in Geneva.

  9. Apotemnophilia, body integrity identity disorder or xenomelia? Psychiatric and neurologic etiologies face each other

    OpenAIRE

    Sedda, Anna; Bottini,Gabriella

    2014-01-01

    Anna Sedda,1,2 Gabriella Bottini1,21Department of Behavioral and Brain Sciences, University of Pavia, Pavia, 2Cognitive Neuropsychology Laboratory, Niguarda Ca’ Granda Hospital, Milan, ItalyAbstract: This review summarizes the available studies of a rare condition in which ­individuals seek the amputation of a healthy limb or desire to be paraplegic. Since 1977, case reports and group studies have been produced, trying to understand the cause of this unusual desire....

  10. P1 peptidase–a mysterious protein of family Potyviridae

    Indian Academy of Sciences (India)

    The coding region for P1 peptidase is located at the very beginning of the viral genome of the family Potyviridae. Until recently P1 was thought of as serine peptidase with ... Jana Rohožková1 Milan Navrátil1. Faculty of Science, Palacký University in Olomouc, Šlechtitelů 11, 783 71, Olomouc-Holice, Czech Republic ...

  11. Low back pain and gastroesophageal reflux in patients with COPD: the disease in the breath

    OpenAIRE

    Bordoni,Bruno; Marelli,Fabiola; Morabito,Bruno; Sacconi,Beatrice; Caiazzo,Philippe; Castagna,Roberto

    2018-01-01

    Bruno Bordoni,1 Fabiola Marelli,2,3 Bruno Morabito,2,3 Beatrice Sacconi,4,5 Philippe Caiazzo,6 Roberto Castagna2 1Foundation Don Carlo Gnocchi IRCCS, Department of Cardiology, Scientific Institute of Hospitalization and Care, Milan, 2Department of Fascial Osteopathic Research, CRESO, School of Osteopathic Centre for Research and Studies, Gorla Minore, 3Department of Fascial Osteopathic Research, CRESO, School of Osteopathic Centre for Research and Studies, Fano, 4Department of Radiological, ...

  12. Polemiche sopra i due massimi sistemi: Galileo e il Piccolo Teatro

    Directory of Open Access Journals (Sweden)

    Sara Colciago

    2017-03-01

    Full Text Available The paper, based on phd dissertation about the relationship between Piccolo Theatre of Milan and local audience community, analyzes the debate rised by catholics politicians around the show Life of Galileo (1963, on the most important italian newspapers and in City Council. These protests, though being speciously raised against that specific show, were an attack towards the artistic independence of Piccolo Theatre, aiming for more pluralism in a public institution financed by the City.

  13. 3cixty: Building comprehensive knowledge bases for city exploration

    OpenAIRE

    Troncy , Raphaël; Rizzo , Giuseppe; Jameson , Anthony; Corcho , Oscar; Plu , Julien; Palumbo , Enrico; Ballesteros Hermida , Juan Carlos; Spirescu , Adrian; Kuhn , Kai-Dominik; Barbu , Catalin; Rossi , Matteo; Celino , Irene; AGARWAL , Rachit; Scanu , Christian; Valla , Massimo

    2017-01-01

    International audience; Planning a visit to Expo Milano 2015 or simply touring in Milan are activities that require a certain amount of a priori knowledge of the city. In this paper, we present the process of building such comprehensive knowledge bases that contain descriptions of events and activities, places and sights, transportation facilities as well as social activities, collected from numerous static, near-and real-time local and global data providers, including hyper local sources suc...

  14. The Port Moresby-Solomons Operation and the Allied Reaction, 27 Apr - 11 May 1942

    Science.gov (United States)

    2012-01-01

    Pacific. It is a powerful example of the value and importance of the Dr. Milan Vego has been a professor in the Joint Mili- tary Operations Department...12 The Combined Fleet intended also to destroy the British Eastern Fleet and capture Ceylon (today, Sri Lanka) and thereby extend Japanese power over...Britain; Kavieng, on New Ireland; Buka Island; Kieta and Buin, on Bougainville; Faisi Island; and Salamaua and Lae on New Guinea.36 The majority of these

  15. [Digital Pen & Paper® technology to manage clinical risk and to prevent medical malpractice claims].

    Science.gov (United States)

    Genovese, Umberto; Del Sordo, Sara; Gerosa, Camillo; Mobilia, Francesca; Raineri, Massimo

    2014-01-01

    The use of innovative technologies in the health sector can be a key element in clinical risk management. In order to reduce errors in medical recording and to provide medico-legal evidence, Digital Pen & Paper technology has been adopted by medical staff of a hospital in Milan. The Authors introduce the first results of this trial: notable advantages have been reported in compilation, transmission and storage of medical records. Furthermore, this technology could provide evidence in evaluating medical malpractice claims.

  16. Validation of the alpha-fetoprotein model for hepatocellular carcinoma recurrence after transplantation in an Asian population.

    Science.gov (United States)

    Rhu, Jinsoo; Kim, Jong Man; Choi, Gyu Seong; Kwon, Choon Hyuck David; Joh, Jae-Won

    2018-02-20

    This study was designed to validate the alpha-fetoprotein model for predicting recurrence after liver transplantation in Korean hepatocellular carcinoma patients. Patients who underwent liver transplantation for hepatocellular carcinoma at Samsung Medical Center between 2007 and 2015 were included. Recurrence, overall survival, and disease-specific survival of patients divided by both the Milan criteria and the alpha-fetoprotein model were compared using Kaplan-Meier log-rank test. The predictability of the alpha-fetoprotein model compared to the Milan criteria was tested by means of net reclassification improvement analysis applied to patients with a follow-up of at least 2 years. A total of 400 patients were included in the study. Patients within Milan criteria had 5-year recurrence, and overall survival rates of 20.9% and 76.3% respectively, compared to corresponding rates of 50.3% and 55.7%, respectively, for patients who were beyond Milan criteria. Alpha-fetoprotein model low risk patients had 5-year recurrence and overall survival rates of 21.1% and 76.2%, respectively, compared to corresponding rates of 57.7% and 52.2%, respectively, in high risk patients (P<0.001, all). Although overall net reclassification improvements were statistically nonsignificant for recurrence (NRI=1.7%, Z=0.30, p=0.7624), and overall survival (NRI=9.0%, Z=1.60, p=0.1098), they were significantly better for predicting no recurrence (NRI=6.6%, Z=3.16, p=0.0016) and no death. (NRI=7.7%, Z=3.65, p=0.0003) CONCLUSIONS: The alpha-fetoprotein model seems to be a promising tool for liver transplantation candidacy, but further investigation is needed.

  17. Gran Sasso: Gallex underway

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Although the experiment actually started collecting its solar neutrino data last Summer, November 30 saw the official inauguration of the Gallex experiment. A collaboration between Heidelberg, Karlsruhe and Munich in Germany, Saclay and Nice in France, Milan and Rome in Italy, Rehovot in Israel and Brookhaven in the US, Gallex uses 30 tonnes of gallium (as gallium chloride solution) to intercept neutrinos from the sun

  18. L.O.T.O. - Landscape Opportunities For Territorial Organization

    Directory of Open Access Journals (Sweden)

    Anna Rossi

    2015-11-01

    Full Text Available The European Union promoted the transnational cooperation project L.O.T.O. (Landscape Opportunities for Territorial Organization by the program Interreg IIIB CADSES. The project gave up the illustration of some outputs in the seminar Landscape opportunities. Guidelines for the landscape management of the territorial transformations (Milan, 2005, October 6th-7th. This paper is a summary of introduction at the project. The attaches are the original reports of the end seminar. 

  19. Breastfeeding Determinants in Healthy Term Newborns

    OpenAIRE

    Colombo, Lorenzo; Crippa, Beatrice Letizia; Consonni, Dario; Bettinelli, Maria Enrica; Agosti, Viola; Mangino, Giulia; Bezze, Elena Nicoletta; Mauri, Paola Agnese; Zanotta, Lidia; Roggero, Paola; Plevani, Laura; Bertoli, Donatella; Giannì, Maria Lorella; Mosca, Fabio

    2018-01-01

    Breastfeeding is the normative standard for infant feeding. Despite its established benefits, different factors can affect breastfeeding rates over time. The purpose of this study was to evaluate breastfeeding determinants in healthy term newborns during the first three months of life. A prospective, observational, single-center study was conducted in the nursery of Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico in Milan, Italy. The mother-baby dyads that were admitted to the Clini...

  20. Otcovství v románech Milana Kundery

    OpenAIRE

    Labudová, Zuzana

    2013-01-01

    This thesis discusses the concept of fatherhood in the novels of Milan Kundera. The first part of the analysis focuses on initiation rituals leadings to the construction of the masculine identity and the future quality fatherhood; this thesis discusses unwanted fatherhood, the phenomenon of the missing father and the ethical aspects of the (non)fatherhood and the theme of fatherhood as a coming to terms with the world. I concentrate on the basic models od fatherhood in Kundera's novels, which...

  1. The FORMAT campaign in summer 2002

    Energy Technology Data Exchange (ETDEWEB)

    Ordonez, C.; Steinbacher, M.; Dommen, J.; Prevot, A.S.H.

    2003-03-01

    Within the framework of the EC project FORMAT (Formaldehyde as a Tracer of Photooxidation in the Troposphere) the Laboratory of Atmospheric Chemistry participated in a field campaign in the Milan area dur-ing summer 2002. Ground and airborne based measurements of formaldehyde and other trace gases were performed in order to enhance the knowledge of the tropospheric distribution of formaldehyde and its influence in photochemical processes. (author)

  2. Diagnosis and management of xerostomia and hyposalivation

    OpenAIRE

    Villa, Alessandro; Connell,Christopher; Abati,Silvio

    2014-01-01

    Alessandro Villa,1,2 Christopher L Connell,3 Silvio Abati4 1Division of Oral Medicine and Dentistry, Brigham and Women’s Hospital, Boston, MA, USA; 2Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA; 3Department of General Dentistry, Boston University Henry M Goldman School of Dental Medicine, Boston, MA, USA; 4Dental Clinic, Department of Health Sciences, University of Milan, Milano, Italy Abstract: Xerostomia, the su...

  3. Optimization of dose and technique for magnetic resonance studies with an oral contrast agent

    International Nuclear Information System (INIS)

    Broglia, L.; Tortora, A.; Maccioni, F.; Arpesani, R.; Marcelli, G.; Ascarelli, A.; Rossi, P.

    1999-01-01

    The aim of the study was to optimize the dose, scan delay and sequences for use in magnetic resonance (MR) studies with an oral contrast agent (FerriSeltz, Bracco Spa, Milan, Italy) to obtain positive or negative contrast enhancement in the bowel lumen. Ferric ammonium citrate, being positive or negative contrast agent according to its dilution, permits to tailor the dose to optimize bowel lumen opacification [it

  4. Oestrus ovis L. (Diptera: Oestridae) Induced Nasal Myiasis in a Dog from Northern Italy

    OpenAIRE

    Sergio A. Zanzani; Luigi Cozzi; Emanuela Olivieri; Alessia L. Gazzonis; Maria Teresa Manfredi

    2016-01-01

    A companion dog from Milan province (northern Italy), presenting with frequent and violent sneezing, underwent rhinoscopy, laryngoscopy, and tracheoscopy procedures. During rhinoscopy, a dipteran larva was isolated from the dog and identified as first instar larval stage of O. ovis by morphological features. Reports of O. ovis in domestic carnivores are sporadic and nevertheless this infestion should be considered as a possible differential diagnosis of rhinitis in domestic carnivores living ...

  5. Treating ischaemia-reperfusion injury with prostaglandin E1 reduces the risk of early hepatocellular carcinoma recurrence following liver transplantation.

    Science.gov (United States)

    Kornberg, A; Witt, U; Kornberg, J; Friess, H; Thrum, K

    2015-11-01

    Surgical stress by hepatic ischaemia-reperfusion (I/R) is supposed to promote intra- and extrahepatic tumour recurrence. Treatment with prostaglandin E1 (PGE1) has been shown to attenuate hepatic I/R injury in liver transplant patients, but the potential anti-cancer effects have not been analysed. To evaluate the impact of PGE1 therapy on risk of hepatocellular carcinoma (HCC) recurrence in liver transplant patients. A retrospective review of 106 liver transplant patients with HCC was conducted. Fifty-nine patients underwent early post-liver transplantation (LT) treatment with the stable PGE1 analogue alprostadil. Administration of alprostadil was correlated with outcome in uni- and multivariate analysis. Subgroup analysis focused on patients with HCC beyond the Milan criteria (Milan Out) on radiographic imaging. Three- and 5-year recurrence-free survival rates were 87.9% and 85.7% in the PGE1-group, but only 65.3% and 63.1% in the non-PGE1-population (P = 0.003). Multivariate Cox regression analysis identified absence of PGE1-treatment (HR = 11.42), along with presence of poor tumour grading (HR = 2.69) and microvascular tumour invasion (HR = 35.8) to be independently associated with early (within 12 months) HCC recurrence. In Milan Out-patients, only therapy with PGE1 (HR = 5.09) and well/moderate tumour differentiation (HR = 6.51) were independent promoters of recurrence-free survival. Treating hepatic ischaemia-reperfusion injury with alprostadil reduces the risk of early HCC recurrence following LT. In particular patients with HCC exceeding the Milan criteria seem to benefit from PGE1-treatment. The molecular mechanisms of the anti-tumour effects need to be further assessed. © 2015 John Wiley & Sons Ltd.

  6. Need for an Ecological Index

    Directory of Open Access Journals (Sweden)

    Rohan Wickramasinghe

    2007-12-01

    Full Text Available The article was published in the Sri Lankan newspaper 'The Island' on the 30th November 2005 after the World Environmental Education Congress (WEEC held in Milan. Author hopes it could provide a base for a project for senior school children or more senior students to devise an Ecological Index and ‘If nothing else, it could help them in thinking out the issues involved!’ Author supposes that could be a form of environmental education.

  7. Persistence, switch rates, drug consumption and costs of biological treatment of rheumatoid arthritis: an observational study in Italy

    OpenAIRE

    Degli Esposti, Luca; Favalli, Ennio Giulio; Sangiorgi, Diego; Di Turi, Roberta; Farina, Giuseppina; Gambera, Marco; Ravasio, Roberto

    2016-01-01

    Luca Degli Esposti,1 Ennio Giulio Favalli,2 Diego Sangiorgi,1 Roberta Di Turi,3 Giuseppina Farina,4 Marco Gambera,5 Roberto Ravasio,6 1CliCon S.r.l. – Health, Economics & Outcomes Research, Ravenna, 2Department of Rheumatology, Istituto Ortopedico Gaetano Pini, Milan, 3Local Pharmaceutical and Supplementary Assistance Unit, Roma Local Health Authority D, Rome, 4Internal Management Control Unit – Pharmaceutical Spending Control Sector, Caserta Local Health ...

  8. Risk Stratification and Effects of the First 24-Hour Pharmacotherapy in Predominantly Hypertensive Patients with Acute Myocardial Infarction

    Czech Academy of Sciences Publication Activity Database

    Peleška, Jan; Grünfeldová, H.; Monhart, Z.; Faltus, Václav; Tomečková, Marie; Ryšavá, D.; Velimský, T.; Ballek, L.; Hubač, J.; Charalampidi, K.

    2009-01-01

    Roč. 27, Suppl. 4 (2009), S421-S422 ISSN 0263-6352. [European Meeting on Hypertension /19./. 12.06.2009-16.06.2009, Milan] R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : pilot registry of acute myocardial infarction * hypertension and other cardiovascular risk factors * first 24-hour pharmacotherapy of myocardial infarction Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  9. Future needs in radiation protection training for NPP workers of Slovenia

    International Nuclear Information System (INIS)

    Kozelj, M.; Bogovic, T.

    1999-01-01

    Short review of history of radiation protection training for NPP workers in Slovenia and legal requirements regarding this field are presented. Courses developed in co-operation between Milan Copic Nuclear Training Centre and Krsko Nuclear Power Plant are briefly described and their implementation presented. Using available data we have predicted probable number of courses and participants in forthcoming years. Some results from inquiry on courses for regularly exposed workers are presented, enabling us to modify courses according to participants' needs.(author)

  10. Phosphorous Management in the Lake Erie Basin. Lake Erie Wastewater Management Study.

    Science.gov (United States)

    1978-01-01

    6,330 9 1,411 Portage : 04195500 (1) Woodville, OH 428 10 : 1,292 Huron : 04199000 (1) Milan, OH 371 11 : 1,543 Sandusky : 04198000 (1) : Fremont...Cuyahoga River : 04206000 (1) : Old Portage , OH : 404 : 58 : 197 Mud Brook : 04206050 (1) : Akron, OH : 29.3 59 : 162 Yellow Creek 04206220 (1...cost are realized. Soil tilth, drainage, and moisture retention are improved. inventoried , particularly with regard to potential for suitability as

  11. Evaluation of bovine-derived lacteal complex supplementation on gene expression in BALB/c mice

    Directory of Open Access Journals (Sweden)

    Clerici M

    2011-09-01

    Full Text Available Mario Clerici1,2, Emmanuel Pauze3, Arienne de Jong3, Mara Biasin1, Larry E Miller41Department of Biomedical Sciences and Technology, University of Milan, Milan, Italy; 2Don C Gnocchi Foundation, IRCCS, Milan, Italy; 3Sprim Advanced Life Sciences, Milan, Italy; 4Sprim USA, San Francisco, CA, USAAbstract: We conducted an evaluation of gene expression associated with innate and adaptive immunity in a double-blind ex vivo mouse study using a bovine-derived dietary ingredient (Ai/E10®, Health Technology Resources, Inc., Scottsdale, AZ, USA. BALB/c female mice (5–6 weeks of age were fed chewy granola bars supplemented with (Test or without (Control Ai/E10 for 10 days. After the feeding period, the animals were sacrificed and spleen cells were isolated and incubated with lipopolysaccharide and phorbol myristate acetate-ionomycin. RNA was extracted and mRNA expression of 84 genes involved in innate and acquired immunity was determined with real-time PCR arrays. Numerous genes associated with innate and adaptive immunity were upregulated in the Test group when stimulated with mitogens. Significant upregulation was observed in 30% (25 of 84 of genes upon lipopolysaccharide stimulation and in 14% (12 of 84 of genes upon phorbol myristate acetate + ionomycin stimulation in the Test group relative to Controls. This study illustrates that Ai/E10 supplementation results in significant and specific upregulation of genes associated with innate and adaptive immunity in mice. Notably, this effect was observed only in stimulated cultures.Keywords: dietary supplementation, immunomodulation, mice

  12. Nitric oxide synthase isoforms in spontaneous and salt hypertension

    Czech Academy of Sciences Publication Activity Database

    Hojná, Silvie; Kuneš, Jaroslav; Zicha, Josef

    2007-01-01

    Roč. 25, Suppl. 2 (2007), S 338-S 338 ISSN 0263-6352. [European Meeting on Hypertension /17./. 15.06.2007-19.06.2007, Milan] R&D Projects: GA MŠk(CZ) 1M0510 Institutional research plan: CEZ:AV0Z50110509 Keywords : nitric oxide synthase isoforms * spontaneous and salt hypertension Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

  13. Audio-visuomotor processing in the Musician's brain: an ERP study on professional violinists and clarinetists

    OpenAIRE

    Mado Proverbio, Alice; Calbi, Marta; Manfredi, Mirella; Zani, Alberto

    2014-01-01

    The temporal dynamics of brain activation during visual and auditory perception of congruent vs. incongruent musical video clips was investigated in 12 musicians from the Milan Conservatory of music and 12 controls. 368 videos of a clarinetist and a violinist playing the same score with their instruments were presented. The sounds were similar in pitch, intensity, rhythm and duration. To produce an audiovisual discrepancy, in half of the trials, the visual information was incongruent with the...

  14. Alcohol and cocaine co-consumption in two European cities assessed by wastewater analysis.

    Science.gov (United States)

    Rodríguez-Álvarez, Tania; Racamonde, Inés; González-Mariño, Iria; Borsotti, Andrea; Rodil, Rosario; Rodríguez, Isaac; Zuccato, Ettore; Quintana, José Benito; Castiglioni, Sara

    2015-12-01

    The quantitative determination of urinary biomarkers in raw wastewater has emerged in recent years as a promising tool for estimating the consumption of illicit drugs, tobacco and alcohol in a population and for comparing local and temporal trends. In this study, a three-year monitoring campaign (2012-2014) was conducted to compare alcohol and cocaine use in two European cities (Santiago de Compostela, Spain, and Milan, Italy) by wastewater analysis. Ethyl sulphate and benzoylecgonine were used, respectively, as biomarkers of ethanol and cocaine consumption and cocaethylene as an indicator of co-consumption of both substances. Biomarkers were measured using liquid chromatography-tandem mass spectrometry and concentrations were converted to rates of consumption using specific correction factors. Results were statistically compared in terms of geographic and temporal tendencies. Alcohol intake was significantly higher in Santiago than in Milan (13.6L versus 5.1L ethanol/1000 people day, averages). Cocaine use was higher in Milan than in Santiago de Compostela (800 versus 632 mg/1000 people day, averages). A significant higher consumption of both alcohol and cocaine was observed during the weekends (~23-75% more than on weekdays) in both cities. In terms of years, slight changes were observed, but no clear trends as representative of the whole year could be identified because of the limited number of days sampled. Co-consumption was evaluated using the cocaethylene/benzoylecgonine ratio, which was higher during the weekend in both cities (58% in Santiago and 47% in Milan over the non-weekend day means), indicating a greater co-consumption when cocaine is used as a recreational drug. Wastewater-based epidemiology gave estimates of alcohol and cocaine use in agreement with previous wastewater studies and with recent European surveillance and prevalence data, and weekly profiles of use and preferential patterns of consumption could be plot. Copyright © 2015 Elsevier B

  15. Analýza vnějšího prostředí pro vybranou firmu

    OpenAIRE

    ONDOKOVÁ, Lucie

    2012-01-01

    The aim of my bachelor thesis was to appreciate the current situation and market position of the building company Milan Hodboď through analysis of external environment.For analyse of external environment I used STEP analyse and Porter´s model of five powers. STEP analyse detects effects from macroenvironment (social and cultural, technical and technological, economic, political and legislative). Porter´s model five forces studies microenvironment (new competition, customers, suppliers, substi...

  16. Un modello informativo parametrico per il Duomo di Milano - Test e sperimentazioni

    OpenAIRE

    Francesca Lo Furno; Federica Pietrucci; Cinzia Tommasi; Alessandro Mandelli

    2017-01-01

    Nowadays, with the spread of the BIM technology in the Cultural Heritage field, it is important to find, case by case, a method that permits to manage the archeological and architectural artifacts considering their personal needs. In this case, the project focuses on a portion of the roofs of the Milan Cathedral, chosen for the complexity and richness in shapes of the components, which leads to difficult survey operations. The target was to experience complex methods of mult...

  17. Conference: “Space and Research: Which future for the coming generation” | 18 September | Uni Mail

    CERN Multimedia

    Stefania Pandolfi

    2015-01-01

      On Friday, 18 September, Luca Parmitano (Major in the Italian Air Force and European Space Agency astronaut), Guido Tonelli (CERN phycisist) and Amalia Ercoli Finzi (Emeritus Professor in the Aerospace department of the Polytechnic University of Milan and a Principal Investigator of the ESA Rosetta spacecraft) will present their visions of the future of research and space exploration. Free entrance. Limited number of seats - registration is essential, click here. For more information contact fc-italie@unige.ch.

  18. JPRS Report, Science & Technology, Europe

    Science.gov (United States)

    1991-08-13

    ascertain to what extent chlorophenols from old sedi- ment ( sewage sludge , for instance) can lead to ground water contamination. Here, there are many...the field of fermentation and bioconversion , generally defined the "traditional" biotechnologies. In the field of "new" biotechnologies, these...metabolites 60 11,000 Farmitalia Carlo Erba, Milan 9 Enzymes with new properties 60 13,000 Tecnofarmaci, Pomezia 10 Bioconversion and enzymatic catalysis for

  19. In Vitro Evaluation of an Injectable Chitosan Gel for Sustained Local Delivery of BMP-2 for Osteoblastic Differentiation

    Science.gov (United States)

    2011-11-01

    Yunqing Kang,1 Daniel A. Young,1 Milan Sen,2 Joseph C. Wenke,3 Yunzhi Yang1 1Department of Restorative Dentistry and Biomaterials, University of Texas...pH value of the chitosan solution was 6.3. The dialyzed chitosan solution was autoclaved at 121C for 20 min, cooled down to room temperature, and...gel formulation. Two different concentrations of BMP-2 were loaded into the dialyzed chitosan solutions and agitated at room tem- perature and cooled

  20. Productive Districts of the Music Industry Supply Chain in Italy

    OpenAIRE

    Ardizzone Antonella

    2012-01-01

    This paper analyzes the spatial concentration of firms in the Italian music industry supplychain, by two different samples and an ad hoc methodology. Results show a relative strongspatial concentration of firms and revenues for every kind of firm considered in Lombardy,Latium and Emilia Romagna Regions of Italy. Milan can be considered the «Italian capital ofmusic» and, according to revenues, the capital of music publishing, radio broadcasting, recording studios and recording industry. The fo...

  1. Solar Trees: First Large-Scale Demonstration of Fully Solution Coated, Semitransparent, Flexible Organic Photovoltaic Modules.

    Science.gov (United States)

    Berny, Stephane; Blouin, Nicolas; Distler, Andreas; Egelhaaf, Hans-Joachim; Krompiec, Michal; Lohr, Andreas; Lozman, Owen R; Morse, Graham E; Nanson, Lana; Pron, Agnieszka; Sauermann, Tobias; Seidler, Nico; Tierney, Steve; Tiwana, Priti; Wagner, Michael; Wilson, Henry

    2016-05-01

    The technology behind a large area array of flexible solar cells with a unique design and semitransparent blue appearance is presented. These modules are implemented in a solar tree installation at the German pavilion in the EXPO2015 in Milan/IT. The modules show power conversion efficiencies of 4.5% and are produced exclusively using standard printing techniques for large-scale production.

  2. Project for a renewable energy research centre

    OpenAIRE

    Andrea Giachetta

    2011-01-01

    In Liguria, where sustainable approaches to the design, construction and management of buildings enjoy scant currency, the idea of a company from Milan (FERA s.r.l.) setting up a research centre for studies into renewable energy resources, could well open up very interesting development opportunities.The project includes: environmental rehabilitation (restoration) projects; strategies for the protection of water resources and waste management systems; passive and active solar systems (solar t...

  3. How to calculate an MMSE score from a MODA score (and vice versa) in patients with Alzheimer's disease.

    Science.gov (United States)

    Cazzaniga, R; Francescani, A; Saetti, C; Spinnler, H

    2003-11-01

    The aim of the present study was to provide a statistically sound way of reciprocally converting scores of the mini-mental state examination (MMSE) and the Milan overall dementia assessment (MODA). A consecutive series of 182 patients with "probable" Alzheimer's disease patients was examined with both tests. MODA and MMSE scores proved to be highly correlated. A formula for converting MODA and MMSE scores was generated.

  4. CTC Sentinel. Volume 6, Issue 11-12, November 2013

    Science.gov (United States)

    2013-11-01

    as well as a clinic for countering magic, jinns (genies) and infertility through use of the Qu’ran.13 Ansar al-Shari`a is also heavily...We found amazing results. Those we sent told us about their psychological relief.”18 It is unlikely that the Libyan government approves of such...Bosnia, but the network in Milan was an important node supplying documents, money and other forms of logistical support for volunteers worldwide

  5. A Musical Italy: Michael W. Balfe’s Italian Experiences

    Directory of Open Access Journals (Sweden)

    Basil Walsh

    2016-06-01

    Full Text Available The Dublin-born musician, Michael W. Balfe, was a singer, composerand conductor whose brilliant musical career was heavily influenced byformative experiences in Italy. In 1825, Balfe, interested in broadeninghis musical studies first went to Paris where he was introduced to thegreat composers, Luigi Cherubini and Gioachino Rossini, who took apersonal interest in him and his musical talents. On the advice of Rossinihe spent the next few years in Italy studying singing with the famousRossini singer, Filippo Galli, and taking music composition lessonsfrom Ferdinando Paer, in Rome. Later in Milan he studied harmonyand counterpoint with Vincenzo Federici. By 1831, when he was only23 years old, his first three operas had been produced in Palermo, Pavia,and Milan. He returned to London in August 1835, participatingwith the great Lablache, Tamburini, Rubini and Grisi in a concert inVauxhall Gardens. In 1834 he made his debut at La Scala, Milan, singingopposite the renowned mezzo-soprano, Maria Malibran in Rossini’sOtello. He appeared again with Malibran in Venice early in 1835,singing once more in Rossini and Bellini operas. Balfe worked as a singerand composer throughout the Italian peninsula/states during the years,1825-1835 and this article will chart these experiences and demonstratehow the time he spent in Italy and the people he met, influenced hislife and later career as an important and popular European composer.

  6. ORIENTEERING CLUB

    CERN Multimedia

    Club d'orientation

    2013-01-01

    Relais inter-club/Challenge Carlo Milan Samedi 28 septembre, à Apples-Ballens (Vd), a eu lieu le relais inter-club avec le Challenge Carlo Milan. 32 équipes étaient présentes pour défendre les couleurs de leur club, que se soit sur le relais technique avec trois coureurs ou sur le relais facile avec deux coureurs. La victoire du relais technique revenait à une équipe du CARE Vevey, quant au relais facile, la première place était pour le club Lausanne-Jorat. Le CO CERN avait à cœur de défendre le challenge Carlo Milan remporté l’an dernier mais il n’a pas pu résister au club du O’Jura, qui plaçait notamment quatre de ses équipes sur les six premières places du relais technique. Les rendez-vous de la coupe genevoise pour les deux prochaines semaines seront: - le vendredi 11 octobre aux Evaux pou...

  7. Proportional Systems in the History of Architecture: A Conversation with James S. Ackerman

    Directory of Open Access Journals (Sweden)

    Matthew A Cohen

    2014-06-01

    Full Text Available In November 2010, James S. Ackerman, today the only living participant of the conference ‘De divina proportione’, which was held in Milan in 1951, sat for a video interview that was later shown at the conference ‘Proportional Systems in the History of Architecture’ in Leiden in 2011 to mark the sixtieth anniversary of the Milan conference. In this interview, conducted by Matthew A. Cohen, Ackerman discusses how the study of proportional systems has changed over the past six decades, and thereby provides a unique link between the two conferences. The interview begins with Ackerman’s experiences in northern Italy at the close of World War II, and a few years later at the Milan conference. It considers prevailing twentieth-century attitudes toward proportion up to the time of the conference, and compares them with prevailing medieval and Renaissance attitudes. Ackerman then shares his thoughts on the works and legacies of Rudolf Wittkower, Le Corbusier and Colin Rowe, before exploring the influences of architectural proportional theory on architectural design, and possible relationships between proportional systems and architectural beauty. After exploring changes in the uses of proportional systems that accompanied the rise of Abstract Expressionism, the arc of the interview concludes with Ackerman’s thoughts about the future of proportional systems in light of the evolving role of the computer in architectural practice today.

  8. Liver transplantation for hepatocellular carcinoma: is zero recurrence theoretically possible?

    Science.gov (United States)

    Irtan, Sabine; Barbier, Louise; Francoz, Claire; Dondero, Federica; Durand, Francois; Belghiti, Jacques

    2016-04-01

    Hepatocellular carcinoma (HCC) recurrence remains a key issue after liver transplantation. This study aimed to determine a subgroup of HCC patients within the Milan criteria who could achieve a theoretical goal of zero recurrence rates after liver transplantation. Between 1999 and 2009, 179 patients who received liver transplantation for HCC within the Milan criteria were retrospectively included. Analysis of the factors associated with HCC recurrence was performed to determine the subgroup of patients at the lowest risk of recurrence. Seventy-two percent of the patients received a bridging therapy, including 54 liver resections. Eleven (6.1%) patients recurred within a delay of 19+/-22 months and ultimately died. Factors associated with recurrence were serum alpha-fetoprotein level >400 ng/mL, satellite nodules, poor differentiation, microvascular invasion and cholangiocarcinoma component. Recurrence rates decreased from 6.1% to 3.1% in patients without any of these factors. Among HCC patients within the Milan criteria, selecting patients with factors based on histology would allow tending towards zero recurrence, and prior histological assessment by liver biopsy or resection may be essential to rule out poorly differentiated tumors, microvascular invasion, and cholangiocarcinoma component.

  9. Liver transplantation for hepatocellular carcinoma: a survey of practices.

    Science.gov (United States)

    Van Kleek, Erik J; Schwartz, Jonathan M; Rayhill, Stephen C; Rosen, Hugo R; Cotler, Scott J

    2006-08-01

    To survey physician practices regarding liver transplantation for patients with hepatocellular carcinoma (HCC). Many issues surrounding liver transplantation for HCC are controversial and physician practices have not been well characterized. Transplant physicians and surgeons were electronically surveyed regarding surveillance, diagnosis, selection criteria for deceased and living donor transplantation, and use of adjunctive therapy for HCC. Eighty-nine of 174 (51%) physicians completed the survey (39 hepatologists, 41 transplant surgeons, and 9 others). Most respondents were from large US transplant centers. All reported screening for HCC during transplant evaluation, and 98% surveyed patients awaiting transplant. Sixty percent of respondents would biopsy lesions under selective conditions, whereas 32% never biopsy lesions, and 8% biopsy all lesions. Eighty two percent of respondents claimed to adhere to the Milan criteria (single lesion Milan criteria. Ninety-six percent of respondents treat HCC before transplantation, and 87% would transplant patients down-staged to meet the Milan criteria. There is consistency related to HCC surveillance and treatment in liver transplant candidates. Variations of responses regarding biopsy of lesions, patient selection for deceased donor and living donor transplantation highlight a need for evidence-based guidelines.

  10. Guido Vegni (1931 - 2016)

    CERN Document Server

    2016-01-01

    Guido Vegni, a renowned particle physicist and Professor at the University of Milan, passed away on Thursday, 2 June.   Professor Guido Vegni in 1976, at the Institute for High Energy Physics in Protvino, Russia. Italian physicist Guido Vegni passed away on Thursday, 2 June. With his death we have lost a friend, an excellent physicist and a strong supporter of the CERN programme. His long and fruitful involvement in particle physics started in the mid 1950s, when he joined the Milan nuclear emulsion group led by Giuseppe Occhialini in 1956. His thesis aimed to measure the spin-parity assignment of the K+ meson from its decay into three pions, contributing to the study of the famous "tau-theta puzzle", eventually solved by the discovery of the non-conservation of parity in weak interactions. In 1960, Guido was appointed "Assistant" to Professor G. Occhialini in Milan, the first step of a career that led to him eventually becom...

  11. Hepatic transplantation outcomes for carefully selected cirrhotic patients with hepatocellular carcinoma: experience at a small- to medium-volume centre.

    LENUS (Irish Health Repository)

    Qasim, A

    2012-02-01

    BACKGROUND: Hepatic transplantation outcomes for cirrhotic patients with hepatocellular carcinoma (HCC) at a small- to medium-volume centre are not fully known due to relative novelty of patient selection criteria. AIM: To determine hepatic transplantation outcomes for HCC at a small- to medium-volume centre. Patients and methods Hepatocellular carcinoma patients were listed for transplantation according to the International Guideline and further categorized as those fulfilling or exceeding Milan or University of San Francisco (UCSF) criteria on explanted liver morphology. Outcomes including mortality, retransplantation, and tumour recurrence rate were analysed. RESULTS: Twenty-six patients had HCC and on explanted liver morphology, Milan and UCSF criteria met 15 and 18 patients, respectively. Patients and graft survival at 3 months, 1 and 5 years were 100, 96, 84, and 88, 84, 77%, respectively. Outcomes favoured Milan criteria but did not reach statistical significance. CONCLUSIONS: Hepatic transplantation for HCC at a small-to medium-volume transplant centre had comparable survival outcomes to high-volume centres.

  12. Development of a sublingual allergy vaccine for grass pollinosis

    Directory of Open Access Journals (Sweden)

    Franco Frati

    2010-06-01

    Full Text Available Franco Frati1,2, Silvia Scurati1, Paola Puccinelli1, Marie David3, Cecile Hilaire4, Maurizio Capecce4, Francesco Marcucci2, Cristoforo Incorvaia51Medical and Scientific Department, Stallergenes, Milan, Italy; 2University Department of Medical and Surgical Specialties and Public Health, Perugia, Italy; 3Laboratoire Stallergenes, Antony, France; 4Marketing Department, Stallergenes, Milan, Italy; 5Allergy/Pulmonary Rehabilitation Unit, ICP Hospital, Milan, ItalyAbstract: Grass pollen is a very common cause of allergic rhinitis and asthma. The only treatment targeting the underlying causes of allergy is immunotherapy (IT. Sublingual immunotherapy (SLIT has been introduced to solve the problem of systemic reactions to subcutaneous IT (SCIT. This article evaluates the characteristics of the allergen extract, Staloral, in terms of practical administration, effectiveness, safety, and mechanism of action. Efficacy data were obtained from double-blind, placebo-controlled studies using Staloral in patients sensitized to grass pollen, while practical administration, cost-effectiveness, and mechanism of action data were provided by well designed studies. The efficacy and safety of Staloral, as demonstrated by review of published studies which used doses up to 1125 times those administered with SCIT, shows that this allergen extract has optimal characteristics for treating patients with seasonal allergies due to grass pollens. The main mechanism of action is the interaction between dendritic cells of the oral mucosa and the subsequent tolerance induced in T-cells.Keywords: allergen extracts, high-dose, efficacy, safety, sublingual immunotherapy

  13. Space Archaeology for military-agricultural colonies (tuntian) on the ancient Silk Road, NW China

    Science.gov (United States)

    Luo, Lei; Wang, Xinyuan; Guo, Huadong; Liu, Chuansheng

    2017-04-01

    The ancient Silk Road, a pioneering work in the history of human civilization, contributed greatly to the cultural exchange between China and the West. It is the precious cultural heritage should be shared by the whole humanity. Although there were countless archaeological sites along the ancient Silk Road, most of the existing researches just focused on the sites, lacking the overall understanding of the relationships between sites and their supporting environment. Space archaeology provides a new viewpoint for investigating, discovering, reconstructing and documenting the archaeological sites under different scales. The tuntian system was a state-promoted system of military-agricultural colonies, which originated in the Western Han dynasty (206 BC-9 AD). All the imperial dynasties in Chinese history adopted the practice of tuntian to cultivate and guard frontier areas as an important state policy for developing border areas and consolidating frontier defence. This study describes the use of Chinese GF-1 imagery, LS-7 ETM+ data and ASTER GDEMV2 products to uncover an ancient irrigated canal-based tuntian system located in Milan oasis adjacent to the ancient Kingdom of Loulan at the southern margin of the Tarim Basin. The GF-1 and LS-7 data were first processed following atmospheric and geometric correction and enhanced by Gram Schmidt pansharpening. The linear archaeological traces of tuntian irrigation canals were extracted from the morphologically enhanced GF-1 PAN imagery using our proposed automatic method which adopts mathematical morphological processing and Canny edge operator. Compared with the manual extractions, the overall detection accuracy was better than 90%. In addition, the functions of the trunk, primary, secondary and tertiary canals were each analyzed and the spatial extent of Milan's tuntian landscape were analyzed with the help of the NDVI derived from the GF-1 multispectral imagery. The effective irrigated tuntian area was estimated to be 2

  14. Treatment of hepatocellular carcinoma (HCC) with intra-arterial Yttrium-90 microspheres for down-staging patients to transplantation

    International Nuclear Information System (INIS)

    De Man, K.; Defreyne, L.; Delanghe, E.; Smeets, P.; Verhelst, X.; Geerts, A.; Van Vlierberghe, H.; Rogiers, X.; Troisi, R.; Lambert, B.

    2015-01-01

    Full text of publication follows. Introduction and aim: in our hospital, patients are referred for intra-arterial treatment with Yttrium-90 microspheres if they present with an HCC confined to the liver, but are ineligible for curative treatment options such as liver transplantation, partial hepatectomy or radio-frequent ablation. Additional eligibility criteria for radio-embolisation consist of Child-P ugh score Milan criteria (single tumour ≤5 cm or ≤ 3 lesions ≤ 3 cm). We recorded whether the patient was down staged to a tumour load complying with the Milan criteria, and if so, whether transplantation was carried out. Results: 40 patients aged <70 years and with a tumour load exceeding the Milan criteria (all treated with TheraSphere, Nordion except 1 with SIR-Spheres, Sirtex) were evaluable. 35 had Barcelona Clinic Liver Cancer (BCLC) B stage disease and 5 had BCLC C. Overall median survival was 12.9 months. 16 out of 40 patients were down staged to the Milan criteria (40%, all BCLC B), of whom 8 were actually transplanted so far. Two patients are on the waiting list, 1 patient refuses to be listed and 1 patient suffers co-morbidity that excludes him from abdominal surgery. Unfortunately 4 patients died before or during work-out for transplantation: 1 unexplained sudden death, 1 lung embolism and 2 due to liver failure. The overall median survival was 30,4 months in the down staged patients. 24 out 40 patients (60%) did not have a tumour load within the Milan criteria at any point of their follow up and had a significant worse

  15. Seasonal changes in nasal cytology in mite-allergic patients

    Directory of Open Access Journals (Sweden)

    Gelardi M

    2014-03-01

    Full Text Available Matteo Gelardi,1 Diego G Peroni,2 Cristoforo Incorvaia,3 Nicola Quaranta,1 Concetta De Luca,1 Salvatore Barberi,4 Ilaria Dell'Albani,5 Massimo Landi,6 Franco Frati,5 Olivier de Beaumont7 1Otolaryngology Unit, Department of Neuroscience and Sensory Organs, University of Bari, Bari, Italy; 2Department of Pediatrics, University of Verona, Verona, Italy; 3Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, Italy; 4Department of Pediatrics, San Paolo Hospital, Milan, Italy; 5Medical and Scientific Department, Stallergenes, Milan, Italy; 6Department of Pediatrics, National Healthcare System, ASL TO1, Turin, Italy; 7Medical Affairs Department, Stallergenes, Antony, France Background: House dust mites (HDMs are a major cause of allergic rhinitis (AR and asthma worldwide. Recent studies suggested that the allergen load presents seasonal modifications, giving rise to seasonal variation in nasal inflammation and symptoms. The aim of this study was to evaluate by nasal cytology whether nasal inflammation in mite-allergic patients changes with the seasons of the year. Methods: The study included 16 patients (seven males and nine females, mean age 38.1 years with persistent AR caused by monosensitization to HDMs. Nasal cytology was performed in all patients once monthly for 1 year. Results: Nasal cytology showed that the cells most commonly detected in the nasal mucosa were neutrophils. During the period from October to April, a peak in the number of neutrophils and also the presence of significant numbers of eosinophils, mast cells, and lymphocytes/plasma cells were found, which shows the occurrence of more intense inflammation during these months. Conclusion: Nasal cytology provides useful data in detecting nasal inflammation and its association with the clinical stage of AR. The seasonal variations in nasal cytology are likely to be induced by the fluctuations in the HDM allergen that have been uncovered in recent investigations. Keywords: allergens

  16. George Baldessin’s first view of the city: The formative influence of the Italian sculptor Alik Cavaliere on George Baldessin

    Directory of Open Access Journals (Sweden)

    Victoria Perin

    2015-04-01

    Full Text Available In Sasha Grishin’s 2014 book, Australian art: a history, he begins his discussion of printmaker-sculptor George Baldessin (1939-1978 with a statement about the artist’s migration to Australia. While this is appropriate, as Baldessin’s art is intimately involved with his relationship to ‘place’, extensive biographical interpretations have meant that the consequences of Baldessin’s life have long overshadowed the consequences of his art. After travelling to Milan in 1962 to study with the internationally renowned Marino Marini, Baldessin found himself under the tutelage of Marini’s lesser-known studio assistant, Alik Cavaliere (1926-1998. Cavaliere’s phenomenological philosophy, which informed his approach to sculpture, formed a foundational basis for Baldessin’s later work in Australia. After his return from Milan, the young artist created works that were derivative of Cavaliere. This was contemporary Milanese art, Melbourne style. Over time this influence became less obvious, and Baldessin slowly transformed Cavaliere’s approach into something idiosyncratic and deeply personal. Yet the basic tenets of Cavaliere’s philosophy remain traceable in Baldessin’s most admired work, the installation produced for the 1975 São Paulo Biennial – the sculpture Occasional screens with seating arrangement with the print suite Occasional images from a city chamber. Cavaliere’s advocacy for works which simulated ‘place’ and being-in-the-world struck a chord with Baldessin. Not least because Baldessin was raised relatively close to Milan, a truth he often obscured.

  17. Impact of air pollution in deterioration of carbonate building materials in Italian urban environments

    International Nuclear Information System (INIS)

    Barca, Donatella; Comite, Valeria; Belfiore, Cristina M.; Bonazza, Alessandra; La Russa, Mauro F.; Ruffolo, Silvestro A.; Crisci, Gino M.; Pezzino, Antonino; Sabbioni, Cristina

    2014-01-01

    Highlights: • Geochemical study of black crusts developed on three monuments located in Milan, Florence and Rome. • Trace element composition of the black crusts is greatly influenced by anthropogenic pollution. • Geochemical characterization of black crusts can be used as a reliable indicator of environmental pollution. - Abstract: This work presents results from a petrographic, morphological and chemical study of the black crusts developing on monuments in three Italian cities, the Cathedral of Milan, the Cathedral of St. Maria del Fiore in Florence, and the Vittoriano Monument in Rome. Black crusts (BCs) were studied with traditional techniques such as optical microscopy (OM), scanning electron microscopy coupled with energy-dispersive X-ray spectrometry (SEM-EDS) and infrared spectroscopic techniques (FT-IR), in combination with laser ablation inductively coupled mass spectrometry (LA-ICP-MS), which has shown itself to be particularly useful in determining concentrations of heavy metals in BCs. Although the BCs of the three monuments show general enrichment in heavy metals with respect to the substrate (S), interesting differences were observed among them. The BCs from Milan are the richest in heavy metals, particularly Pb and Zn, reflecting the severe air pollution of this very large city, which, in addition to its intense traffic, is located in the most highly industrialized area of Northern Italy. The BCs from the south-eastern side of the Cathedral of St. Maria del Fiore in Florence, facing a pedestrian area, show little enrichment in heavy metals, and those from the Vittoriano Monument in Rome, which is exposed to intense road traffic, display variable enrichment, attributable to mobile emission sources. Results show that the various enrichment trends in heavy metals observed in the BCs of these three monuments are due to many factors: various sources of anthropogenic pollution, sampling height, exposure, orientation, and the shape of the deposition

  18. Time of hepatocellular carcinoma recurrence after liver resection and alpha-fetoprotein are important prognostic factors for salvage liver transplantation.

    Science.gov (United States)

    Lee, Sanghoon; Hyuck David Kwon, Choon; Man Kim, Jong; Joh, Jae-Won; Woon Paik, Seung; Kim, Bong-Wan; Wang, Hee-Jung; Lee, Kwang-Woong; Suh, Kyung-Suk; Lee, Suk-Koo

    2014-09-01

    Salvage liver transplantation (LT) is considered a feasible option for the treatment of recurrent hepatocellular carcinoma (HCC). We performed this multicenter study to assess the risk factors associated with the recurrence of HCC and patient survival after salvage LT. Between January 2000 and December 2011, 101 patients who had previously undergone liver resection (LR) for HCC underwent LT at 3 transplant centers in Korea. Sixty-nine patients' data were retrospectively reviewed for the analysis. The recurrence of HCC was diagnosed at a median of 10.6 months after the initial LR, and patients underwent salvage LT. Recurrences were within the Milan criteria in 48 cases and were outside the Milan criteria in 21 cases. After salvage LT, 31 patients had HCC recurrence during a median follow-up period of 24.5 months. There were 24 deaths, and 20 were due to HCC recurrence. The 5-year overall survival rate was approximately 54.6%, and the 5-year recurrence-free survival rate was 49.3%. HCC recurrence within the 8 months after LR [hazard ratio (HR) = 3.124, P = 0.009], an alpha-fetoprotein level higher than 200 ng/mL (HR = 2.609, P = 0.02), and HCC outside the Milan criteria at salvage LT (HR = 2.219, P = 0.03) were independent risk factors for poor recurrence-free survival after salvage LT. In conclusion, the timing and extent of HCC recurrence after primary LR both play significant roles in the outcome of salvage LT. © 2014 American Association for the Study of Liver Diseases.

  19. Topical antiinflammatory activity of an innovative aqueous formulation of actichelated propolis vs two commercial propolis formulations.

    Science.gov (United States)

    Sosa, Silvio; Bornancin, Anna; Tubaro, Aurelia; Loggia, Roberto Della

    2007-09-01

    A novel aqueous commercial formulation of a new hydrophilic propolis product (Actichelated((R)) Propolis, contained in 'LeniGola PropolEffect Spray Senza Alcohol'; Pharbenia, Milan, Italy) was evaluated for its topical antiinflammatory activity in comparison with a hydroglyceric propolis spray solution ('Propoli LeniGola Spray Senza Alcool'; Pharbenia, Milan, Italy) and a hydroalcohol preparation ('Propoli LeniGola Spray Forte'; Pharbenia, Milan, Italy). Actichelated propolis (Actimex, Trieste, Italy) is a multicomposite material obtained with a patented technology, mechano-chemical activation, which application led to a new hydrosoluble form of propolis. Each propolis preparation provoked a dose-dependent inhibition of the croton oil-induced ear oedema in mice. Considering the administered doses of flavonoids, 'LeniGola PropolEffect Spray Senza Alcool' (ID(50) = 13.6 microL/cm(2), corresponding to 13.6 microg flavonoids/cm(2)) is slightly more active than the hydroglyceric formulation 'Propoli LeniGola Spray' (ID(50) = 13.7 microL/cm(2), corresponding to 20.6 microg flavonoids/cm(2)) and six times more active than the hydroalcohol preparation 'Propoli LeniGola Spray Forte' (ID(50) = 5.5 microL/cm(2), corresponding to 82.5 microg flavonoids/cm(2)). As a reference, 15 microL/cm(2) of the commercial sprays Tantum Verde and Froben, containing 37.5 or 45 microg of the non-steroidal antiinflammatory drugs benzidamine hydrochloride or flurbiprofen, induced 18% and 35% oedema inhibition, respectively.

  20. Identifying cardiac syncope based on clinical history: a literature-based model tested in four independent datasets.

    Science.gov (United States)

    Berecki-Gisolf, Janneke; Sheldon, Aaron; Wieling, Wouter; van Dijk, Nynke; Costantino, Giorgio; Furlan, Raffaello; Shen, Win-Kuang; Sheldon, Robert

    2013-01-01

    We aimed to develop and test a literature-based model for symptoms that associate with cardiac causes of syncope. Seven studies (the derivation sample) reporting ≥2 predictors of cardiac syncope were identified (4 Italian, 1 Swiss, 1 Canadian, and 1 from the United States). From these, 10 criteria were identified as diagnostic predictors. The conditional probability of each predictor was calculated by summation of the reported frequencies. A model of conditional probabilities and a priori probabilities of cardiac syncope was constructed. The model was tested in four datasets of patients with syncope (the test sample) from Calgary (n=670; 21% had cardiac syncope), Amsterdam (n=503; 9%), Milan (n=689; 5%) and Rochester (3877; 11%). In the derivation sample ten variables were significantly associated with cardiac syncope: age, gender, structural heart disease, low number of spells, brief or absent prodrome, supine syncope, effort syncope, and absence of nausea, diaphoresis and blurred vision. Fitting the test datasets to the full model gave C-statistics of 0.87 (Calgary), 0.84 (Amsterdam), 0.72 (Milan) and 0.71 (Rochester). Model sensitivity and specificity were 92% and 68% for Calgary, 86% and 67% for Amsterdam, 76% and 59% for Milan, and 73% and 52% for Rochester. A model with 5 variables (age, gender, structural heart disease, low number of spells, and lack of prodromal symptoms) was as accurate as the total set. A simple literature-based Bayesian model of historical criteria can distinguish patients with cardiac syncope from other patients with syncope with moderate accuracy.

  1. Identifying cardiac syncope based on clinical history: a literature-based model tested in four independent datasets.

    Directory of Open Access Journals (Sweden)

    Janneke Berecki-Gisolf

    Full Text Available BACKGROUND: We aimed to develop and test a literature-based model for symptoms that associate with cardiac causes of syncope. METHODS AND RESULTS: Seven studies (the derivation sample reporting ≥2 predictors of cardiac syncope were identified (4 Italian, 1 Swiss, 1 Canadian, and 1 from the United States. From these, 10 criteria were identified as diagnostic predictors. The conditional probability of each predictor was calculated by summation of the reported frequencies. A model of conditional probabilities and a priori probabilities of cardiac syncope was constructed. The model was tested in four datasets of patients with syncope (the test sample from Calgary (n=670; 21% had cardiac syncope, Amsterdam (n=503; 9%, Milan (n=689; 5% and Rochester (3877; 11%. In the derivation sample ten variables were significantly associated with cardiac syncope: age, gender, structural heart disease, low number of spells, brief or absent prodrome, supine syncope, effort syncope, and absence of nausea, diaphoresis and blurred vision. Fitting the test datasets to the full model gave C-statistics of 0.87 (Calgary, 0.84 (Amsterdam, 0.72 (Milan and 0.71 (Rochester. Model sensitivity and specificity were 92% and 68% for Calgary, 86% and 67% for Amsterdam, 76% and 59% for Milan, and 73% and 52% for Rochester. A model with 5 variables (age, gender, structural heart disease, low number of spells, and lack of prodromal symptoms was as accurate as the total set. CONCLUSION: A simple literature-based Bayesian model of historical criteria can distinguish patients with cardiac syncope from other patients with syncope with moderate accuracy.

  2. Requirements for acquiring a high-quality house dust mite extract for allergen immunotherapy

    Directory of Open Access Journals (Sweden)

    Frati F

    2012-05-01

    Full Text Available Franco Frati,1 Cristoforo Incorvaia,2 Marie David,3 Silvia Scurati,3 Simona Seta,4 Guglielmo Padua,4 Eleonora Cattaneo,1 Carlo Cavaliere,5 Alessia Di Rienzo,6 Ilaria Dell'Albani,1 Paola Puccinelli11Medical and Scientific and Regulatory Department, Stallergenes, Milan, Italy; 2Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, Italy; 3Laboratoire Stallergenes, Antony, France; 4Marketing Department, Stallergenes, Milan, Italy; 5Ear, Nose and Throat Department, University Sapienza, Rome, Italy; 6Azienda Sanitaria Locale, Allergology Service, Frosinone, ItalyAbstract: The house dust mite is a major cause of respiratory allergy worldwide. The management of mite allergy is based on avoidance measures, drug treatment, and allergen immunotherapy, but only allergen immunotherapy is able to modify the natural history of the disease. Injectable subcutaneous immunotherapy was introduced a century ago, while sublingual immunotherapy was proposed in the 1980s and emerged in the ensuing years as an effective and safe option to subcutaneous immunotherapy. However, the quality of the extracts to be used in allergen immunotherapy is crucial for the success of treatment. The mite extract for sublingual immunotherapy known as Staloral 300 was developed to offer optimal characteristics concerning the mite culture medium, standardization, and allergen dose. Double-blind, placebo-controlled trials with Staloral 300 have provided a substantial part of the clinical evidence analyzed in a meta-analysis of the efficacy of allergen immunotherapy in mite-induced rhinitis and asthma. Safety and tolerability are very good, mild local reactions in the mouth being the most common side effect. This makes it feasible to carry out sublingual immunotherapy for the 3–5-year duration needed to achieve long-lasting tolerance to the specific allergen. The performance of Staloral 300 may provide optimal conditions for an effective and safe sublingual immunotherapy in patients with

  3. Visualizing the data city social media as a source of knowledge for urban planning and management

    CERN Document Server

    Ciuccarelli, Paolo; Simeone, Luca

    2014-01-01

    This book investigates novel methods and technologies for the collection, analysis, and representation of real-time user-generated data at the urban scale in order to explore potential scenarios for more participatory design, planning, and management processes. For this purpose, the authors present a set of experiments conducted in collaboration with urban stakeholders at various levels (including citizens, city administrators, urban planners, local industries, and NGOs) in Milan and New York in 2012. It is examined whether geo-tagged and user-generated content can be of value in the creation

  4. Art Meta-4

    DEFF Research Database (Denmark)

    Mehlsen, Camilla; Jensen, Hans Siggaard

    2003-01-01

    Managing through Variety: The European Style. 3rd European Academy of Management (EURAM) Conference , Milan (Italy). 2003 Short description: This paper focuses on the use of art metaphors in today?s world of management and organizational practice. Abstract: This paper focuses on the use of art...... metaphors in today?s world of management and organizational practice. It tells the story of how art has entered the organizational stage as a metaphorical role model and how art is a metaphor we live and manage by. The story is in particular concerned with artistic images of organizations that frame...

  5. Systems Engineering Capstone Marketplace

    Science.gov (United States)

    2017-06-05

    Anchoring System  Stevens Institute of Technology Dr. Milan Simonovic NEW:  TBD/Fatigue  Testing  Applicable  to  both  Humans  and  Animals   (Spring...Essentially,!Fabricated!Equipment!is!a!tool!to!conduct!the!research!as! opposed !to!being!the!focus!of! research!itself.!!An!explicit!prototyping!activity!in...fabrication!must!be!carried!out!according!to!a! plan!that!does!not!require! experimentation !with!concepts!or!with!the!approach.!!The!development!of!the

  6. Knowledge Communication in Green Corporate Marketing

    DEFF Research Database (Denmark)

    Maier, Carmen Daniela

    2011-01-01

    This article explores how several types of knowledge are communicated through the simultaneous deployment of two semiotic modes in the Milan video existing on GE Corporation's website. The video is part of the Ecomagination marketing campaign promoting environmentally friendly products...... and positioning GE as an eco-friendly corporation. The specific aim of my analytical endeavor is to identify how the meaning-making potentials of language and images are integrated, and how this multimodal integration influences the persuasive communication of knowledge types. Key words: multimodal discourse...... analysis; knowledge communication; environmental discourse; green corporate marketing...

  7. Building trust with the schoolchildren in the nuclear training centre

    International Nuclear Information System (INIS)

    Stritar, Andrej; Istenie, Radko

    1995-01-01

    Although Krsko Nuclear Power Plant has been in operation for more than ten years, comparatively little has been done in the field of systematic education and public information. Deficiencies in this field are causing serious misunderstandings about the role of nuclear power and is having a negative impact on its public acceptance. At The Nuclear Training Centre Milan Copic (NTC) in Ljubljana we have prepared a presentation on nuclear energy encompassing a short description of a PWR nuclear power plant, importance of nuclear power in the world and in Slovenia, basic ideas of nuclear safety and radioactive waste disposal

  8. Accumulation of heavy metals in some herbaceous plants collected in urban areas; Indagine sull`accumulo di metalli pesanti in piante erbacee raccolte in aree urbane

    Energy Technology Data Exchange (ETDEWEB)

    Giusto, Domenico; Pedrani, Fabio [Milan, Univ. (Italy). Dipt. di Scienze dell`Ambiente e del Territorio

    1997-06-01

    The amount of some heavy metals [zinc (Zn), copper (Cu), manganese (Mn) and lead (Pb)] accumulated in Lolium perenne, Plantago major, Poa annua, Polygonum aviculare, Taraxacum officinale e Trifolium pratense is reported. The herbaceous plants were collected since 1990 three times every year (spring, summer and autumn) in urban areas in Milan and in one area in the countryside near Monza. In this work the data for the year 1994 are reported. In this year a decrease of the amount of lead compared with the previous years is noted.

  9. TÜ magistritöid 2007 / Tiia Margus, Hille Roots

    Index Scriptorium Estoniae

    Margus, Tiia

    2008-01-01

    Teiste hulgas Tartu Ülikooli eesti ja üldkeeleteaduse instituudis kaitstud magistritöödest eesti keele, uurali keelte, üldkeeleteaduse, arvutilingvistika, eesti keel võõrkeelena, eesti keele ja kirjanduse õpetaja, mitte-eesti kooli eesti keele ja kirjanduse õpetaja erialadel. Teiste hulgas: Marja Unt "Eesti luule 1968-1988 luulearutluse peeglis"; Maarja Hollo "Eksiil kirjanduses. August Mälgu "Kodumaata" ja Isaac Bashevis Singeri "Eksinud Ameerikasse" ning Bernard Kangro Joonatani-romaanide ja Milan Kundera "Teadmatuse" võrdlev vaatlus"; Sigrid Int "20. sajandi kirjanikke: Marta Sillaotsa kultuurivahendustegevus".

  10. Three Roman Innkeepers

    OpenAIRE

    Tatarin, Milovan

    2009-01-01

    In the critical publication of Dundo Maroje which in 1930 was edited for the seventh book of the edition Stari pisci hrvatski (Old Croatian writers) by Milan Rešetar, »three Roman innkeepers« are named as dramatis personae. They appear on the stage three times: act one, scene one; act two, scene nine; act four, scene nine. The aim of this work is to establish how many inns and how many innkeepers appear in the comedy and are their lines mixed.

  11. Debating as an educational method to science and citizenship

    Directory of Open Access Journals (Sweden)

    Sara Calcagnini

    2007-09-01

    Full Text Available If one of aims of science today is to respond to the real needs of society, it must find a new way to communicate with people and to be acquainted with their opinions and knowledge. Many science museums in Europe are adopting new ways to actively engage the public in the debate on topical scientific issues. The Museum of Science and Technology "Leonardo da Vinci" in Milan (partner of the SEDEC project has thus experimented some formats for dialogue with teachers and with the public in general. Our experience shows that museums can be places where science and the public on the one hand and democracy on the other meet.

  12. Public opinion about nuclear energy. Year 2005 poll

    International Nuclear Information System (INIS)

    Istenic, R.; Jencic, I.

    2005-01-01

    Public information is one of the important permanent activities of the Nuclear Training Centre Milan Copic at Jozef Stefan Institute in Ljubljana. It is focused on youngsters and about one half of every generation of schoolchildren in Slovenia is informed on nuclear energy. Every year since 1993 we poll youngsters using the same basic set of questions. For comparison we also polled professionals (our colleagues at the Jozef Stefan Institute) using the same questionnaire. Opinion of youngsters about nuclear energy in Slovenia can be considered favourable now (71 %), but the trend is negative. The support is dropping from initial 83% for two consecutive years. Opposition to NPP Krsko operation remains low. (author)

  13. Research of conceptual art synthesis in contemporary literary criticism

    Directory of Open Access Journals (Sweden)

    Марія Миколаївна Чобанюк

    2016-11-01

    Full Text Available Identity of conceptual art synthesis of the literature of the second half of the XX - XXI century are revealed for the first time in literary criticism in the light of a single system approach (based on creative works of John Fowles, Graham Green, Kurt Vonnegut, Günter Grass, Joseph Heller, Milan Kundera, Mario Vargas Llosa and its theoretical and methodological principles are specified. Efficiency of conceptual art synthesis to the study approach of the works of above mentioned writers is substantiated

  14. “It’s a cosmetic world”

    Directory of Open Access Journals (Sweden)

    Didier Aubert

    2011-04-01

    Full Text Available When I called him in early February, fine art-documentary-advertising photographer Larry Fink was just returning from men’s fashion week in Milan. The occasion for the trip was an exhibit of his work in collaboration with one of his regular clients, Woolrich Woolen Mills. Fink had shot the clothing company’s catalogue several times, but this was a different project. Documentary pictures of the logging community he had taken in the 1980s were used as background for a fashion show evoking “Man ...

  15. L'espansione della criminalità organizzata nell'attività di impresa al Nord

    Directory of Open Access Journals (Sweden)

    Alberto Alessandri

    2016-12-01

    Full Text Available La presente ricerca, realizzata nell’ambito del Dipartimento di Studi Giuridici dell’Università Bocconi di Milano, si è proposta lo scopo di accertare empiricamente l’attività di contrasto all’infiltrazione mafiosa nelle attività economiche da parte della Procura e del Tribunale di Milano, nel periodo 2000 – 2015. Sono stati consultati, nella loro interezza, tutti i fascicoli dei procedimenti penali aperti (e accessibili nel periodo e per i quali vi sia stato un provvedimento di chiusura delle indagini preliminari. Poi è stata sono stati seguiti i processi fino in Cassazione. Sono stati inoltre considerati i fascicoli e i provvedimenti definitivi emessi dal Tribale di Prevenzione di Milano, riferiti allo stesso arco temporale, con attenzione centrata alle misure patrimoniali. Si è dato conto anche dei flussi dei procedimenti riguardanti aventi ad oggetto l’art. 416-bis c.p., oltre che del Tribunale di Milano, di quelli di Roma, Napoli, Reggio Calabria, Palermo. I dati ricavati dai fascicoli sono stati elaborati con un apposito software, per ottenere le correlazioni e le statistiche ritenute di maggior interesse, in specie riguardo alla penetrazione nel settore economico e imprenditoriale. Parole chiave: mafia; criminalità organizzata; ‘ndrangheta; attività economiche; Italia settentrionale.   This research, conducted within the Department of Law of Bocconi University in Milan, aims to empirically ascertain the actions implemented by the Office of the Public Prosecution and the Court of Milan to counteract the Mafia’s infiltration in economic activities in the period from 2000 to 2015. All the records pertaining to criminal proceedings opened (and accessible in the relevant period - and in relation to which preliminary investigations were closed - were consulted in their entirety. The proceedings were then followed up until the Court of Cassation. In addition, all the records and final decisions issued by the Tribunale di

  16. Public opinion about nuclear energy. Year 2006 poll

    International Nuclear Information System (INIS)

    Istenic, R.; Jencic, I.; Tkavc, M.

    2006-01-01

    Public information, one of the important activities of the Nuclear Training Centre Milan Copic at the Jozef Stefan Institute in Ljubljana, is focused on youngsters. Almost one half of every generation of schoolchildren in Slovenia is informed on nuclear energy by live lectures, exhibition, publications and laboratory demonstrations. To measure the opinion of youngsters about nuclear power and get a feed-back for our activities about 1000 youngsters are polled every year since 1993 using the same basic set of questions. Continued operation of the NPP Krsko is supported by 76% of youngsters in Slovenia (slightly positive trend from the last year's 71%). Opposition to NPP Krsko operation remains low. (author)

  17. Mechanical behavior of a total chest wall prosthesis with rib-like features.

    Science.gov (United States)

    Girotti, A; Rosa, F; Ferrotto, M; Girotti, P; Pastorino, U

    2017-11-01

    The Department of Thoracic Surgery of the National Institute of Cancer in Milan developed a new rib-cage prosthesis which tries to combine flexibility, protection and bio-compatibility. This new replacement concept has been implanted in many patients, showing cheering results in term of reconstructions simplicity, postoperative complications reduction and patients comfort. This paper investigates and discusses in detail the mechanical behavior of the innovative rib cage prosthesis. Mechanical strength and stiffness are numerically evaluated in order to asses its limits and if it is fully compatible with patients 'normal' life.

  18. Lugares de la memoria, lugares de la ausencia en la poesía de Fabio Morábito

    Directory of Open Access Journals (Sweden)

    Fabiola Fernandez Adechedera

    2015-12-01

    Full Text Available This article proposes interpreting Fabio Morábito’s poetry taking into account its autobiographical features. The author´s biography places him in a geographical and linguistic displacement through Egypt, Italy and Mexico. Thereby, we analyze some poems that allow us to identify the presence of a personal memory referred to specific scenes of his childhood in Milan and his house moving to Mexico City. Such scenes settle the distinctive aspect of Morabito’s discursive identity, marked by uprooting, mobility and loss, essential topics of his poetry.

  19. A historical report on Riccardo Galeazzi and the management of Galeazzi fractures.

    Science.gov (United States)

    Sebastin, Sandeep J; Chung, Kevin C

    2010-11-01

    Fracture of the shaft of the radius associated with a dislocation of the distal radioulnar joint is an uncommon injury. In 1934, Riccardo Galeazzi of Milan reported his experience with the management of 18 such cases before the Lombard Surgical Society and subsequently received the eponym for this injury. Galeazzi was one of Italy's pioneering orthopedic surgeons, with an extensive bibliography that included nearly 150 publications. This article examines the evolution of management of the Galeazzi fracture and sheds light on this notable physician's life. Copyright © 2010 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  20. Literatura europea, literaturas europeas

    OpenAIRE

    Cabanilles Sanchis, Antonia; Lozano de la Pola, Ana

    2014-01-01

    Para Milan Kundera el hecho de que Europa no haya conseguido pensar su literatura como una unidad histórica supone un fracaso intelectual irreparable. Sin embargo, aunque los intentos de componer esa Historia no han cesado, urge en las circunstancias actuales pensar esa unidad, imaginar una Europa que no dependa de los mercados, de los bancos ni tampoco de la política económica y turística. La diversidad y la voluntad de mantener las diferencias, que identifica a Europa, debería ir acompañada...

  1. STEFANO RODOTA IN MEMORIAM

    OpenAIRE

    Antillón, Walter

    2017-01-01

    En su inmortal opúsculo De los Delitos y de las Penas (1764), Cesare Bonesana, Marqués de Beccaria, milanés rico y de antiguo linaje, se expresó acerca del derecho de propiedad llamándolo “terrible, y quizá no necesario derecho” (pág. 189 de la edición española de Trotta, Madrid, 2011); una circunstancia que en mi memoria viene siempre asociada a la persona y a la obra del admirable jurista italiano Stefano Rodotà, fallecido ayer [el 23 de junio de 2017].

  2. De Statuis: christian sources on the “Riot of statues”

    Directory of Open Access Journals (Sweden)

    Alberto J. Quiroga Puertas

    2016-12-01

    Full Text Available The historical account of the “Riot of the Statues” of A.D. 387 Antioch found in Christian authors coetaneous to the event and from the Vth century A.D. is provided from different literary genres but approached with common narrative lines. The decisive intervention of the Meletian group of the Antiochene Church in order to obtain the emperor Theodosius’ forgiveness and his portrait as a submissive ruler to Christian figures are the main leitmotifs in the accounts of John Chrysostom, Ambrose of Milan, Sozomenus and Theodoretus of Cyr.

  3. JPRS Report, East Europe.

    Science.gov (United States)

    1992-11-19

    22161 East Europe JPRS-EER-92-160 CONTENTS 19 November 1992 BULGARIA Commodity Markets Trade With Albania [168 CHASA 13 OctJ 1 Personality...93CH0068A Prague CESKY DENIK in Czech 24 0ct92p 1 [Commentary by Milan Caha: "Consent as a Bribe "] [Text] The crisis around the Gabcikovo-Nagymarosz hydro...solution based on using the Danube’s original riverbed, the Czech representation underesti- mated the situation. Consent to variant C became a bribe to

  4. [Demand of diagnosis and treatment for work-related psycho-social discomfort: trend of phenomenon].

    Science.gov (United States)

    Punzi, S; Castellini, G; Cassitto, M G; Leocata, G; Costa, G

    2011-01-01

    This study is aimed at updating the knowledge on case records of workers examined at the "Center for Occupational Stress and Harassment" of the "Clinica del Lavoro Luigi Devoto" in Milan. A sample of patients examined between 2009 and 2011 (n = 198) was compared with a sample examined in 2003 (n = 226). Compared to the past case records, the latter sample included a significantly higher number of graduates (chi2 = 6.6; p micro/small enterprises (chi2 = 41.9; p < 0.001). Company changes and organizational conflicts were the main antecedents for workplace bullying.

  5. Professional Monograph Review

    Directory of Open Access Journals (Sweden)

    Mildeová Stanislava

    2008-10-01

    Full Text Available Title of the monograph: Systems Approach to Knowledge Modelling. Authors: dr. Ludmila Dömeová; dr. Milan Houška; dr. Martina Houšková Beránková. Cover designer: Olga Čermáková. Interior designer: Roman Kvasnička. Publisher: Graphical Studio Olga Čermáková, Czech Republic. Place: Hradec Králové, Czech Republic. Year of publication: 2008. Number of pages: 282. Recommended price of the book: 39.90 EUR. First edition. Reviewer : dr. Stanislava Mildeová; Department of Systems Analysis, Faculty of Informatics and Statistics, University of Economics, Prague.

  6. National serum bio bank

    International Nuclear Information System (INIS)

    Poli, F.; Facchiano, F.

    2009-01-01

    The Italian Bio bank is hosted at 'Ospedale Maggiore. Policlinico' of Milan. This structure occupies an area of 300 sq meters and includes laboratories and a cryogenic area. This facility has been built a in compliance with the standards defined by the Foundation for Accreditation of Cellular Therapy (FACT) mostly related to adequacy of spaces, equipment and governmental and institutional policies for bio safety. The Cryogenic area follows written procedures in the event of an ambient disaster and for safety personnel and of the samples stored

  7. Actual performance of mechanical ventilators in ICU: a multicentric quality control study

    OpenAIRE

    Govoni,; Dellacà ,; Penuelas,; Bellani,; Artigas,Antonio; Ferrer,; Navajas,Daniel; Pedotti,; Farre,Ramon

    2012-01-01

    Leonardo Govoni,1 Raffaele L Dellaca,1 Oscar Peñuelas,2,3 Giacomo Bellani,4,5 Antonio Artigas,3,6 Miquel Ferrer,3,7 Daniel Navajas,3,8,9 Antonio Pedotti,1 Ramon Farré3,81TBM-Lab, Dipartimento di Bioingegneria, Politecnico di Milano University, Milano, Italy; 2Hospital Universitario de Getafe – CIBERES, Madrid, Spain; 3CIBER de Enfermedades Respiratorias, Bunyola, Spain; 4Department of Experimental Medicine, University of Milan, Bicocca, Italy; 5Department of Pe...

  8. Electron emission from laser irradiating target normal sheath acceleration (TNSA)

    Czech Academy of Sciences Publication Activity Database

    Torrisi, L.; Cutroneo, Mariapompea

    2016-01-01

    Roč. 171, 9-10 (2016), s. 754-765 ISSN 1042-0150. [12th Workshop on European Collaboration for Higher Education and Research in Nuclear Engineering and Radiological Protection. Bologna, Catania, Milan, 30.05.2016-01.06.2016] R&D Projects: GA ČR(CZ) GBP108/12/G108; GA MŠk LM2015056 Institutional support: RVO:61389005 Keywords : electron emission from plasma * TNSA * TOF * SiC * plastic scintillator * Thomson parabola spectrometer Subject RIV: BH - Optics, Masers, Lasers Impact factor: 0.443, year: 2016

  9. Staging Shakespeare. Renato Sarti’s “rude mechanicals” (tragic comedy

    Directory of Open Access Journals (Sweden)

    Maddalena Giovannelli

    2017-11-01

    Full Text Available "The same person," according to Socrates, "should know how to write comedy and tragedy; anybody who excels at tragedy will also be a master of comedy." Shakespeare's work, seeing its many registers and styles, seems to fully confirm Socrates' statement. But too often, on the most important stages in Italy, the tragic dimension of Shakespeare's plays prevails, and the actors seem to orient their actorial style in that direction. Yet with the Bard you can laugh, in actual fact you must laugh. Renato Sarti, director of Milan's "Teatro della Cooperativa" (Cooperativa Theatre, artistic director and playwright, seems to embody, through his own theatrical productions, the versatility of genre Socrates advocated.

  10. Cost-effectiveness analysis on the use of rFSH + rLH for the treatment of anovulation in hypogonadotropic hypogonadal women

    Directory of Open Access Journals (Sweden)

    Papaleo E

    2014-06-01

    Full Text Available Enrico Papaleo,1 Carlo Alviggi,2 Giorgio Lorenzo Colombo,3,4 Claudio Pisanelli,5,6 Claudio Ripellino,7 Salvatore Longobardi,8 Pier Luigi Canonico91Centro Scienze della Natalità, Gynecological-Obstetrics Department, San Raffaele Hospital, Vita-Salute San Raffaele, Milan, Italy; 2Department of Neuroscience, Reproductive Sciences and Odontostomatology, University “Federico II” of Naples, Naples, Italy; 3Department of Drug Sciences, University of Pavia, Pavia, Italy; 4SAVE Studi Analisi Valutazioni Economiche, Milan, Italy; 5ACO San Filippo Neri, Rome, Italy; 6Società Italiana Di Farmacia Ospedaliera, Milan, Italy; 7CSD Medical Research Srl, Milan, Italy; 8Medical Department, Merck Serono SpA, Rome, Italy; 9Department of Pharmaceutical Sciences, University of Piemonte Orientale, Novara, Italy Background: Hypogonadotropic hypogonadal women are characterized by ovarian functionality deficiency, caused by low concentrations of follicle-stimulating hormone (FSH and luteinizing hormone (LH. To recover reproduction functionality, recommended therapies for ovarian induction involve injections of FSH and LH medications. Objective: Since important differences exist between recombinant and urinary gonadotropin therapies in terms of efficacy and cost, the objective of this study was to develop a cost-effectiveness model to compare recombinant FSH (rFSH + recombinant LH (rLH and highly purified human menopausal gonadotropin (HP-HMG. Methods: A Markov model was developed, considering three cycles of therapy; probability of pregnancy and miscarriage were considered, and the efficacy was evaluated in terms of pregnancy occurrence. The perspective of the model was that of the Italian Health Service, so only direct cost (drugs, specialist visits, patient examinations, and hospitalizations were included. Results: rFSH + rLH is associated with a higher total cost (€3,453.50 and higher efficacy (0.87 compared with HP-HMG (€2,719.70 and 0.50. rFSH + r

  11. Composição dramática e maiêutica no Teeteto de Platão

    Directory of Open Access Journals (Sweden)

    Dennys Garcia Xavier

    2007-06-01

    Full Text Available My aim in this article is, through a concise analysis of the “socratic” midwifery digression, try to demonstrate the measure in which the Theaetetus characters choice establish the nature of the debate developed in the dialoghe. Emphasizing the Tübigen-Milan ermeneutical criterion, we also try to sketch a biographical profile of those characters – in a complete harmony with Plato´s written theory – to a correct adjustment of perspective on reading the dialoghe and bring into focus some of the mathematical arguments extracted from the VII book of the Republic, essencial to the Theaetetus philosophical drama.

  12. Simple heuristics in over-the-counter drug choices: a new hint for medical education and practice

    Directory of Open Access Journals (Sweden)

    Silvia Riva

    2011-02-01

    Full Text Available Silvia Riva1–3, Marco Monti2, Alessandro Antonietti11Department of Psychology, Catholic University of the Sacred Heart of Milan, Milan, Italy; 2Department for Adaptive Behaviour and Cognition, Max Planck Institute for Human Development Berlin, Germany; 3Department of Medicine and Medical Specialities, ABB Centre, University of Milan and IRCCS Ca’ Granda Foundation, Maggiore Hospital, Milan, ItalyIntroduction: Over-the-counter (OTC drugs are widely available and often purchased by consumers without advice from a health care provider. Many people rely on self-management of medications to treat common medical conditions. Although OTC medications are regulated by the National and the International Health and Drug Administration, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions.Purpose: This study examined how subjects make their decisions to select an OTC drug, evaluating the role of cognitive heuristics which are simple and adaptive rules that help the decision-making process of people in everyday contexts.Subjects and methods: By analyzing 70 subjects’ information-search and decision-making behavior when selecting OTC drugs, we examined the heuristics they applied in order to assess whether simple decision-making processes were also accurate and relevant. Subjects were tested with a sequence of two experimental tests based on a computerized Java system devised to analyze participants’ choices in a virtual environment.Results: We found that subjects’ information-search behavior reflected the use of fast and frugal heuristics. In addition, although the heuristics which correctly predicted subjects’ decisions implied significantly fewer cues on average than the subjects did in the information-search task, they were accurate in describing order of information search. A simple combination of a fast and frugal tree and a tallying rule predicted more than 78% of subjects

  13. Downstream the hall EHN1

    CERN Document Server

    1978-01-01

    Jura is towards left, Saleve towards right. Starting from left the photo shows the area behind NA5 (not shown) where later the EHS (European Hybrid Spectrometer) was installed; the neutron beam line N4 to NA6 (neutron elastic scattering at very small angle, by the Freiburg-Moscow (ITEP) Collaboration); the E4/H4 beam line to NA1 (Photoproduction of vector and scalar bosons by the Frascati-Milan-Pisa-Roma (FRAMM) Collaboration); the area of the H6 beam, behind NA3.

  14. On the Effects of Atmospheric Particles Contamination and Humidity on Tin Corrosion

    DEFF Research Database (Denmark)

    D’Angelo, L.; Verdingovas, V.; Ferrero, L.

    2017-01-01

    The effects of hygroscopic atmospheric particles are investigated in relation to the corrosion of tin. Surface insulation resistance test boards were directly contaminated both with ambient particles sampled in the field at Milan, Italy, and with pure saline particles generated in the laboratory....... The effects of the adsorption/desorption kinetics and of the temperature on the deliquescence and crystallization RH values were also investigated. Leakage current measurements at 5-V dc highlighted the ability of atmospheric particles to promote corrosion and electrochemical migration at RH levels far below...

  15. An interview with Ali M. Ahad

    DEFF Research Database (Denmark)

    Zoppi, Marco

    2017-01-01

    Ali Mumin Ahad is a Somali scholar with multifaceted interests and a personal life story that brought him from Somalia to Italy, and now to Australia. Ali obtained his undergraduate degree in Economics at the Somali National University, and then moved to Italy where he earned his master’s degree...... in agribusiness at Università Cattolica del Sacro Cuore, in Milan. His doctorate was awarded by La Trobe University in Australia, while he now holds a position as Honorary Research Fellow at Melbourne University, Faculty of Arts. In his works, Ali focuses on Somali history, including colonialism, on literature...

  16. Weak oil prices seen hindrance to pace of increase in gas use

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    World demand for gas is expected to rocket, yet future natural gas and liquefied natural gas projects remain threatened by the link of gas prices to crude oil prices. This is the main message that emerged from the 19th World Gas Conference in Milan last week. A number of reports predicted regional demand for gas. All foresaw a rise. International Gas Union (IGU), organizer of the conference, and said world natural gas production has continued to rise despite a significant downturn in industrial production. The paper discusses gas demand in Europe, the correlation between oil and gas prices, the natural gas industry in Indonesia, Russia, and southern Europe

  17. Nuclear and radiation safety in Slovenia. Annual report 1997

    International Nuclear Information System (INIS)

    1998-01-01

    The Slovenian Nuclear Safety Administration (SNSA), in co-operation with the Health Inspectorate of the Republic of Slovenia, the Administration for Civil Protection and Disaster Relief and the Ministry of the Interior, has prepared a Report on Nuclear and Radiation Safety in the Republic of Slovenia for 1997. This is one of the regular forms of reporting on the work of the Administration to the Government and National Assembly of the Republic of Slovenia. Contributions to the report were furthermore prepared by competent authorities in the field of nuclear safety: the Agency for Radwaste Management (ARAO), the Milan Copic Nuclear Training Centre, etc. The report contains 17 chapters. (author)

  18. Migration and Literature

    DEFF Research Database (Denmark)

    Frank, Søren

    We live in an age of migration and more and more authors have migrant backgrounds. Migration and Literature offers a thorough and thought provoking examination of the thematic and formal role of migration in four contemporary and canonized novelists, Günter Grass, Milan Kundera, Salman Rushdie, a......, and Jan Kjærstad. This book examines how these novelists reflect, problematize, and "resolve" the problems set by the migratory world and analyzes how the novels employ discursive strategies which emphasize their migratory and homeless form....

  19. A comparison between the administration of oral prolonged-release oxycodone-naloxone and transdermal fentanyl in patients with moderate-to-severe cancer pain: a propensity score analysis

    Directory of Open Access Journals (Sweden)

    Roberto A

    2017-09-01

    Full Text Available A Roberto,1 MT Greco,2 L Legramandi,3 F Galli,3 M Galli,4 O Corli1 1Pain and Palliative Care Research Unit, Oncology Department, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy, 2Department of Clinical Sciences and Community, University of Milan, Milan, Italy, 3Methodology for Clinical Research Laboratory, Oncology Department, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy, 4Scientific Medical Communication srl, Novara, Italy Background: Opioids are the most important pharmacological treatment for moderate-to-severe cancer pain, but side effects limit their use. Transdermal fentanyl (TDF and oral prolonged-release oxycodone-naloxone (OXN-PR are effective in controlling chronic pain, with less constipation compared to other opioids. However, TDF and OXN-PR have never been directly compared.Patients and methods: Cancer patients with moderate-to-severe chronic pain were consecutively enrolled in two prospective 28-day trials, received either TDF or OXN-PR, and were assessed at baseline and after 7, 14, 21, and 28 days. The primary endpoint was 28-day analgesic response rate (average pain intensity decrease ≥30% from baseline. Other outcome measures included opioid daily dose changes over time; need for adjuvant analgesics; number of switches; premature discontinuation; presence and severity of constipation; and other adverse drug reactions. To compare the efficacy and the safety of TDF and OXN-PR, we used the propensity score analysis to adjust for heterogeneity between the two patient groups.Results: Three hundred ten out of 336 patients originally treated (119 TDF and 191 OXN-PR were included in the comparative analysis. The amount of responders was comparable after TDF (75.3% and OXN-PR administration (82.9%, not significant [NS]. The final opioid daily dose expressed as morphine equivalent was 113.6 mg for TDF and 44.5 mg for OXN-PR (p<0.0001. A daily opioid dose escalation >5% was less common after

  20. Public opinion about nuclear energy. Year 2007 poll

    International Nuclear Information System (INIS)

    Istenic, R.; Jencic, I.

    2007-01-01

    Nuclear Training Centre Milan Copic (Izobrazevalni center za jedrsko tehnologijo - ICJT) at Jozef Stefan Institute in Ljubljana incorporates the Information Centre for general public. Most of the visitors are youngsters and almost one half of every generation of schoolchildren in Slovenia is informed on nuclear energy by live lectures, exhibition, publications and laboratory demonstrations. About 1000 visitors are polled every year since 1993 to measure the opinion about nuclear power and get a feed-back for our activities. Continued operation of NPP Krsko is supported by 69% of youngsters (negative trend from the last year's 76%), while opposition remains low. (author)

  1. Science and Technology Text Mining: Nonlinear Dynamics

    Science.gov (United States)

    2004-02-01

    BUCHNER--J UCLA USA 5 CASATI--G UNIV MILAN ITALY 5 ELNASCHIE--MS CORNELL UNIV USA 5 EPSTEIN--IR BRANDEIS UNIV USA 5 ERTL--G MAX PLANCK GESELL GERMANY 5 The...BRISTOL ENGLAND 235 ARNOLD VI RUSSIAN ACADEMY OF SCIENCE RUSSIA 230 TAKENS F UNIV GRONINGEN NETHERLANDS 212 GASPARD P FREE UNIV BRUSSELS BELGIUM 199...IR BRANDEIS UNIV USA 5 ERTL--G MAX PLANCK GESELL GERMANY 5 Nonlinear Dynamics Text Mining References Page 11 The regional mix of authors has some major

  2. Upregulation of apical sodium-chloride cotransporter and basolateral chloride channels is responsible for the maintenance of salt-sensitive hypertension.

    Science.gov (United States)

    Capasso, Giovambattista; Rizzo, Maria; Garavaglia, Maria Lisa; Trepiccione, Francesco; Zacchia, Miriam; Mugione, Alessandra; Ferrari, Patrizia; Paulmichl, Markus; Lang, Florian; Loffing, Johannes; Carrel, Monique; Damiano, Sara; Wagner, Carsten A; Bianchi, Giuseppe; Meyer, Giuliano

    2008-08-01

    We investigated which of the NaCl transporters are involved in the maintenance of salt-sensitive hypertension. Milan hypertensive (MHS) rats were studied 3 mo after birth. In MHS, compared with normotensive strain (MNS), mRNA abundance, quantified by competitive PCR on isolated tubules, was unchanged, both for Na+/H+ isoform 3 (NHE3) and Na+-K+-2Cl- (NKCC2), but higher (119%, n = 5, P salt-sensitive hypertension, there is a strong upregulation, both of NCC and ClC-K along the DCT, which explains the persistence of hypertension.

  3. Bibliographie : Mensonge, tromperie, simulation et dissimulation

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Cavaillé

    2012-10-01

    Full Text Available [nota bene : on excusera le caractère lacunaire de ce recensement, en voie de constitution. Pour toute correction, ajout, remarque etc. merci d’écrire à son auteur]I- SourcesI.1. Antiquité gréco-latine, patristique Aristote (pseudo, Physiognomonie et anonyme latin, Traité de Physiognomonie, cf. textes et traduction italienne, Milan, 1993. Aristote, Ethique à Nicomaque, traduction par J. Tricot, Vrin, 1990 (7e tirage. Augustin d’hippone, De mendacio (Du mensonge, Œuvres de saint Augustin, 1...

  4. The case of Via Barzoni 11. ‘Tailored’ participatory planning of social housing

    Directory of Open Access Journals (Sweden)

    Paolo Carli

    2012-10-01

    Full Text Available The social housing complex located in Via Barzoni 11, Milan, was singled out in 2009 for a demolition and rebuilding plan, featuring a volume growth, strongly opposed by the inhabitants. Between April and June 2012 ALER1 Milano, with the involvement of Comune di Milano – Direzione Casa2, commissioned a working group supervised by Anna Delera, Politecnico di Milano, to devise an alternative plan aiming at preserving the social and typological characteristics of the complex, in order to enforce the sustainability and the direct involvement of the inhabitants in a process of participatory planning.

  5. Design, Production, and Installation of Wooden Walls for the Japan Pavilion at Expo 2015

    Directory of Open Access Journals (Sweden)

    Matteo Cipollini

    2016-10-01

    Full Text Available This article illustrates the production process, the structural calculations and the assembly phases of the wooden walls of the Japan Pavilion at Expo 2015 in Milan, designed by Atsushi Kitagawara Architects (AKA. The pavilion, one of the most popular construction of this international event, was built almost exclusively with precast interlocking. The production process and the assembly phases were optimized to construct the wooden walls (with a height of 4–12 m in a short time frame and with a high level of quality. Out-of-plane rocking and other aspects of structural safety were considered, to ensure sufficient stability of the walls.

  6. Multitemporal burnt area mapping using Landsat 8: merging multiple burnt area indices to highlight burnt areas

    CSIR Research Space (South Africa)

    Vhengani, L

    2015-07-01

    Full Text Available stream_source_info Vhengani_2015_ABSTRACT.pdf.txt stream_content_type text/plain stream_size 1055 Content-Encoding ISO-8859-1 stream_name Vhengani_2015_ABSTRACT.pdf.txt Content-Type text/plain; charset=ISO-8859-1 2015... IEEE International Geoscience and Remote Sensing Symposium (IGARSS), Milan, Italy, 26-31 July 2015 Multitemporal burnt area mapping using Landsat 8: Merging multiple burnt area indices to highlight burnt areas Lufuno Vhengani, Philip Frost...

  7. A Silicon Hadron Calorimeter Module Operated in a Strong Magnetic Field with VLSI Readout for LHC

    CERN Multimedia

    2002-01-01

    % RD35 \\\\ \\\\ On the basis of a cost optimized Silicon production technology we proposed to build a hadron calorimeter active plane. \\\\ \\\\The production of detectors is closely followed and final quality control is performed according to specifications. \\\\ \\\\The technology designed for the cheap pad detector production is applied for the coarse strip detector manufacturing. These strip detectors will be used in the preshower of the electromagnetic calorimeter of CMS. \\footnote{Research & Prod. Assoc. ELMA, RSFSR} \\footnote{Byelorussian State Univ. Minsk} \\footnote{Research & Prod. Comp. SIAPS, RSFSR} \\footnote{Joffe Physical-Technical Inst. RSFSR} \\footnote{Ansaldo Richerche spa, Genoa} \\footnote{SGS-THOMSON, Castelletto, Milan}

  8. THE SOUTH PAYS FOR THE NORTH: FINANCING THE THIRTY YEARS’ WAR FROM NAPLES, 1622-1644

    Directory of Open Access Journals (Sweden)

    Antonio Calabria

    2002-01-01

    Full Text Available This paper examines the severe fiscal offensive which the Spanish Monarchy unleashed in the Kingdom of Naples during the Thirty Years’ War (1618-1648. Though the war was fought far from its borders, Naples was burdened with a whole range of new fiscal measures designed to aid the wareffort in Northern Europe and to protect the state of Milan from the contingencies of war. This paper provides a quantitative analysis of that burden. It uses archival fiscal documents to examine the various expedients Spain used to finance its designs and to plot their incidence from 1622 to1644.

  9. The idea of education and the contemporary world

    Directory of Open Access Journals (Sweden)

    Petrović Aleksandar M.

    2016-01-01

    Full Text Available In a copious introduction to the very problem of education, the author of the study - The Philosophy of Education (Belgrade: Serbian State Publisher of Textbooks, Belgrade, 2016, Milan Uzelac, describes all the main articulated moments, which formed and directed the development of education on a social and historic level. The bases of his conceptions of education are phenomenological, elaborated in a methodological continuum. Through a thouroughful critical review of the current, in general very disappointing state of education in our country, Uzelac points to new, possible directions of development of education.

  10. Mecanismos discursivos de promoción de eventos en la Web: los titulares de las Expos

    Directory of Open Access Journals (Sweden)

    María José Rodrigo Mora

    2012-02-01

    Full Text Available This paper is in line with a national research project (PRIN about the Language of Tourism in Spanish and Italian: Lexical, Pragmatic and Intercultural Aspects. Our aim is to contribute to the study of digital tourist texts adopting a methodological perspective based on the most recent studies about the rhetoric of advertising, web advertising and institutional communication. We carry out a contrastive analysis of the headlines introducing news and press releases published on line within five promotional and touristic websites, those of the expositions of Sevilla (1992, Zaragoza (2008, Shanghai (2010, Italian pavilion, Shanghai (2010, Spanish pavilion, and Milan (2015.

  11. Calvatone: gli scavi del vicus romano di Bedriacum

    Directory of Open Access Journals (Sweden)

    Stefano Nava

    2014-08-01

    Full Text Available The excavations conducted by the University of Milan for almost thirty years at Calvatone (CR, directed by Prof. Maria Teresa Grassi, have been focused on bringing to light the remains of the Roman vicus of Bedriacum, which has been an important strategic and commercial centre on the Via Postumia. Since 2011 fieldworks and campaigns devoted to the study of artefacts have been accompanied by educational activities in order to valorize the historical and archaeological significance of the site and make the discoveries accessible to a wider public.

  12. Life cycle design and design management strategies in fashion apparel manufacturing

    Science.gov (United States)

    Tutia, R.; Mendes, FD; Ventura, A.

    2017-10-01

    The generation of solid textile waste in the process of development and clothing production is an error that causes serious damages to the environment and must be minimized. The greatest volume of textile residues is generated by the department of cut, such as textiles parings and snips that are not used in the productive process. (MILAN et al, 2007). One way to conceive new products environmently conscious is turned to the adoption of a methodology based on Life Cycle Design (LCD) and Design Management.

  13. Intersection how enterprise design bridges the gap between business, technology, and people

    CERN Document Server

    Guenther, Milan

    2012-01-01

    Many organizations struggle with the dynamics and the complexity of today''s social ecosystems that connect everyone and everything, everywhere and all the time. Facing challenges at the intersection of business models, technical developments, and human needs, modern enterprises must overcome the siloed thinking and isolated efforts of the past, and instead address their relationships to people holistically. In Intersection, Milan Guenther introduces a Strategic Design approach that aligns the overarching efforts of Branding, Enterprise Architecture, and Experience Design, and sets them on a

  14. El inicio de la vivienda obrera en Barcelona : las casas baratas (1928-1931), origen, evolución y final de una tipología : un testimonio del desarrollo urbano de la ciudad.

    OpenAIRE

    Morales Ramírez, Gabriela

    2015-01-01

    Eduard Aunós, Milans del Bosch, Baró de Viver y Ramon Albó fueron los primeros barrios obreros de la ciudad de Barcelona. Su construcción se realiza entre 1928 y 1931, durante la dictadura de Miguel Primo de Rivera. Los asentamientos —integrados por agrupaciones de Casas Baratas — se insertaron en un contexto rural y a pesar de la aparente “colonización” que éstos ejercieron sobre su territorio, no establecieron un orden urbano fuera de sus propios límites, ya que la parcelación y ejes del...

  15. ESMO-ESGO-ESTRO consensus conference on endometrial cancer

    DEFF Research Database (Denmark)

    Colombo, Nicoletta; Creutzberg, Carien; Amant, Frederic

    2015-01-01

    The first joint European Society for Medical Oncology (ESMO), European SocieTy for Radiotherapy & Oncology (ESTRO) and European Society of Gynaecological Oncology (ESGO) consensus conference on endometrial cancer was held on 11-13 December 2014 in Milan, Italy, and comprised a multidisciplinary...... panel of 40 leading experts in the management of endometrial cancer. Before the conference, the expert panel prepared three clinically-relevant questions about endometrial cancer relating to the following four areas: Prevention and screening, surgery, adjuvant treatment and advanced and recurrent...

  16. Mobbing prevention and types of assistance to the victims

    Directory of Open Access Journals (Sweden)

    Kostelić-Martić Andreja

    2006-01-01

    Full Text Available Mobbing - psychological abuse at workplace is a phenomenon perpetually existing in the work organizations. Exceedingly important is to detect mobbing in the work organizations before it educe wide and severe effects not only on the victim, but also on the work organization itself. In this article, the mobbing prevention at the level of work organization, health and legal system is discussed. The types of victim assistance are also addressed. Moreover, the author’s experience in working with mobbing victims at the Work Clinic in Milan, i.e. in the ‘Center for prevention, diagnosis, treatment and rehabilitation of occupational maladjustment, is briefly described. .

  17. User preference for a portable syringe pump for iloprost infusion

    Directory of Open Access Journals (Sweden)

    Laria A

    2015-05-01

    Full Text Available Antonella Laria,1 Alfredo Maria Lurati,1 Katia Angela Re,1 Maria Grazia Marrazza,1 Daniela Mazzocchi,1 Alberto Farina,2 Magda Scarpellini,1 1Department of Rheumatology, Fornaroli Hospital, Magenta, Milan, Italy; 2Medical Affairs Department, Italfarmaco S.p.A., Cinisello Balsamo, Milan, Italy Purpose: Administration of intravenous iloprost – a first-line European League Against Rheumatism (EULAR-recommended choice for the treatment of scleroderma (SSc-related digital vasculopathy – requires repeated treatment cycles of 6 hours per day in a hospital setting. During the infusion, patient mobility is considerably restricted due to the size and fixity of traditional syringe pumps. The aim of this study was to evaluate the satisfaction level of patients and nurses, after the introduction of a new portable syringe pump (Infonde®, Italfarmaco S.p.A., Milan, Italy at the Department of Rheumatology, Magenta Hospital, Milan, Italy. Patients and methods: Thirty-four consecutive SSc patients receiving stable therapy with iloprost, previously administered with a fixed pump, were treated using the portable Infonde® pump. Patients (n=34 and nurses (n=4 were asked to answer a nine- and six-item questionnaire, respectively, to assess the satisfaction of the administration comparing the new device versus the previous one. The health care staff of the ward developed the questionnaire, and the response scores ranged from 0 (fixed device better to 10 (portable device better; thus a score >5 indicates a preference for Infonde®. Results: Patients' answers indicated a preference towards the new portable syringe pump, versus the previous fixed pump. Questionnaires administered to patients generated a total of 306 responses, with over 95% of the responses in the range 8–10, of which 89% had a score equal to 10. The responses of nurses showed a score equal to 10 in 100% cases. No significant adverse events were recorded, indicating no change in the tolerability

  18. 3D Visualization of Cultural Heritage Artefacts with Virtual Reality devices

    Science.gov (United States)

    Gonizzi Barsanti, S.; Caruso, G.; Micoli, L. L.; Covarrubias Rodriguez, M.; Guidi, G.

    2015-08-01

    Although 3D models are useful to preserve the information about historical artefacts, the potential of these digital contents are not fully accomplished until they are not used to interactively communicate their significance to non-specialists. Starting from this consideration, a new way to provide museum visitors with more information was investigated. The research is aimed at valorising and making more accessible the Egyptian funeral objects exhibited in the Sforza Castle in Milan. The results of the research will be used for the renewal of the current exhibition, at the Archaeological Museum in Milan, by making it more attractive. A 3D virtual interactive scenario regarding the "path of the dead", an important ritual in ancient Egypt, was realized to augment the experience and the comprehension of the public through interactivity. Four important artefacts were considered for this scope: two ushabty, a wooden sarcophagus and a heart scarab. The scenario was realized by integrating low-cost Virtual Reality technologies, as the Oculus Rift DK2 and the Leap Motion controller, and implementing a specific software by using Unity. The 3D models were implemented by adding responsive points of interest in relation to important symbols or features of the artefact. This allows highlighting single parts of the artefact in order to better identify the hieroglyphs and provide their translation. The paper describes the process for optimizing the 3D models, the implementation of the interactive scenario and the results of some test that have been carried out in the lab.

  19. A multidisciplinary approach to scars: a narrative review

    Directory of Open Access Journals (Sweden)

    Zanier E

    2015-08-01

    Full Text Available Emiliano Zanier,1,2 Bruno Bordoni1,3 1AITOP (Accademia Italiana Terapia Osteopatica Posturale, Castelvetro (MO, Italy; 2EdiAcademy, Milan, Italy; 3Department of Cardiology, Santa Maria Nascente Institute IRCCS, Don Carlo Gnocchi Foundation, Milan, Italy Abstract: The purpose of this article is to carry out a narrative review regarding the approach to scars through complementary and alternative medicine focusing on osteopathy, naturopathy, and other minor methods and traditional rehabilitative medicines, such as physiotherapy and manual therapies. We analyzed the existing literature regarding the possible influences of techniques relaxing the diaphragm – both manual and psychophysical relaxing techniques – and the consequent local response to events leading to scar tissue healing. The objective of the study is to become a useful instrument of knowledge for those manual therapists and professionals who deal with patients affected by discontinuity of the skin surface due to trauma or surgery. This article also intends to stimulate research in order to find and propose new methods of scar treatment, taking into consideration the information gained so far from other complementary and alternative disciplines. Keywords: scar, wound, complementary and alternative medicine, osteopathy, naturopathy

  20. Emerging perspectives on laminopathies

    Directory of Open Access Journals (Sweden)

    Lattanzi G

    2016-04-01

    Full Text Available Giovanna Lattanzi,1,2 Sara Benedetti,3 Maria Rosaria D’Apice,4 Lorenzo Maggi,5 Nicola Carboni,6 Emanuela Scarano,7 Luisa Politano8 1National Research Council of Italy, Institute for Molecular Genetics (CNR-IGM, Unit of Bologna, 2Rizzoli Orthopedic Institute, Laboratory of Musculoskeletal Cell Biology, Bologna, 3Laboratory of Clinical Molecular Biology and Cytogenetics, San Raffaele Scientific Institute, Milan, 4Fondazione Policlinico Tor Vergata, Rome, 5Neuromuscular Diseases and Neuroimmunology Unit, IRCCS Neurological Institute C Besta, Milan, 6Division of Neurology, Hospital San Francesco, Nuoro, 7Pediatric Endocrinology and Rare Diseases Unit, Department of Pediatrics, S Orsola-Malpighi University Hospital, University of Bologna, Bologna, 8Department of Experimental Medicine, Cardiomyology and Medical Genetics, Second University of Naples, Naples, Italy Abstract: Laminopathies are a group of inherited disorders caused by mutations in the lamin A/C gene, and can affect diverse organs or tissues, or can be systemic, causing premature aging. In the present review, we report on the composition and structure of the nuclear lamina and the role of lamins in nuclear mechanics and their involvement in human diseases, and provide some examples of laminopathies and current therapeutic approaches. Keywords: lamin A/C, emerin, laminopathies, Emery–Dreifuss muscular dystrophy, Hutchinson–Gilford progeria

  1. Monitoring and Prediction of Traffic Noise in Large Urban Areas

    Directory of Open Access Journals (Sweden)

    Giovanni Zambon

    2018-02-01

    Full Text Available Dynamap, a co-financed project by the European Commission through the Life+ 2013 program, aims at developing a dynamic approach for noise mapping that is capable of updating environmental noise levels through a direct link with a limited number of noise monitoring terminals. Dynamap is based on the idea of finding a suitable set of roads that display similar traffic noise behavior (temporal noise profile over an entire day so that one can group them together into a single noise map. Each map thus represents a group of road stretches whose traffic noise will be updated periodically, typically every five minutes during daily hours and every hour during night. The information regarding traffic noise will be taken continuously from a small number of monitoring stations (typically 24 appropriately distributed over the urban zone of interest. To achieve this goal, we have performed a detailed analysis of traffic noise data, recorded every second from 93 monitoring stations randomly distributed over the entire urban area of the City of Milan. Our results are presented for a restricted area, the urban Zone 9 of Milan. We have separated the entire set of (about 2000 stretches into six groups, each one represented by a noise map, and gave a prescription for the locations of the future 24 monitoring stations. From our analysis, it is estimated that the mean overall error for each group of stretches (noise map, averaged over the 24 h, is about 2 dB.

  2. Intestinal parasites of owned dogs and cats from metropolitan and micropolitan areas: prevalence, zoonotic risks, and pet owner awareness in northern Italy.

    Science.gov (United States)

    Zanzani, Sergio Aurelio; Gazzonis, Alessia Libera; Scarpa, Paola; Berrilli, Federica; Manfredi, Maria Teresa

    2014-01-01

    Intestinal parasites of dogs and cats are cosmopolitan pathogens with zoonotic potential for humans. Our investigation considered their diffusion in dogs and cats from northern Italy areas, specifically the metropolitan area of Milan and two micropolitan areas of neighboring provinces. It included the study of the level of awareness in pet owners of the zoonotic potential from these parasites. A total of 409 fresh fecal samples were collected from household dogs and cats for copromicroscopic analysis and detection of Giardia duodenalis coproantigens. The assemblages of Giardia were also identified. A questionnaire about intestinal parasites biology and zoonotic potential was submitted to 185 pet owners. The overall prevalence of intestinal parasites resulted higher in cats (47.37%-60.42%) and dogs (57.41%-43.02%) from micropolitan areas than that from the metropolis of Milan (dogs: P = 28.16%; cats: P = 32.58 %). The zoonotic parasites infecting pets under investigation were T. canis and T. cati, T. vulpis, Ancylostomatidae, and G. duodenalis assemblage A. Only 49.19% of pet owners showed to be aware of the risks for human health from canine and feline intestinal parasites. Parasitological results in pets and awareness determination in their owners clearly highlight how the role of veterinarians is important in indicating correct and widespread behaviors to reduce risks of infection for pets and humans in urban areas.

  3. FEDERICO BORROMEO E I «RAGIONAMENTI» INTORNO ALLA «FESTA DELLE LINGUE»

    Directory of Open Access Journals (Sweden)

    Edoardo Buroni

    2017-03-01

    Full Text Available Figura di spicco della Milano secentesca, il cardinale Federico Borromeo resta legato nell’immaginario collettivo al personaggio del capolavoro manzoniano, mentre più limitati e più recenti sono gli studi che ne hanno analizzato direttamente l’ampia produzione scrittoria. Particolare interesse rivestono in questo senso i Sacri ragionamenti, le prediche tenute dall’arcivescovo e da lui stesso raccolte in lingua italiana, di cui qui si propone un breve studio relativamente alle omelie pentecostali. «Reasoning» regarding the «festival of languages» in 17th century Milan. Notes on the thought and language of Federico Borromeo A leading figure in 17th century Milan, Cardinal Federico Borromeo remains tied to the character in Manzoni's masterpiece in the collective imagination, while fewer, more recent studies have directly analyzed his written production. Of special interest in this regard are his Sacred writings, the sermons given by the Archbishop which he himself collected in Italian. We propose a brief study of the Pentecostal sermons.

  4. Orienteering Club

    CERN Multimedia

    Club d'Orientation

    2012-01-01

    Relais inter-club/Challenge Carlo Milan Samedi dernier, lors de l’épreuve de course d’orientation organisée par le club du O’Jura, le moteur de la discipline était l’esprit d’équipe, puisqu’il était question d’un relais inter-club avec le Challenge Carlo Milan. Les clubs avaient aligné leurs coureurs soit sur le relais technique (trois participants) soit sur le relais facile (deux participants). Côté O’Jura, il fallait noter la participation de François Gonon, champion du monde 2011, côté club du CERN, Marie et Gaëtan Vuitton, jeunes espoirs du club, devaient préparer la piste pour lancer le dernier relayeur. Côté Lausanne-Jorat, il fallait compter sur le très jeune Viktor Kuznetsov. Les 31 équipes engagées n’ont pas m&ea...

  5. Sexually Transmitted Infections: A Novel Screening Strategy for Improving Women’s Health in Vulnerable Populations

    Directory of Open Access Journals (Sweden)

    Elena R. Frati

    2017-06-01

    Full Text Available Background: Migrant women are one of the most vulnerable population to health problems and well-being. This study aimed at implementing a counseling and preventive strategy for sexually transmitted infections (STIs in undocumented migrant women in Milan, Italy. Methods: Women (ages 18–65 were enrolled at the NAGA Centre (2012–2013 and asked for a urine sample in order to carry out molecular detection of Human papillomavirus (HPV, Chlamydia trachomatis (Ct, Trichomonas vaginalis (Tv, Neisseria gonorrhoeae (Ng-DNA. Socio-demographic and sexual behavior information were collected. All HPV/Ct+ women were offered Pap tests and/or were prescribed antibiotic treatment. Results: 537/757 women participated in the study (acceptability rate: 70.9%. Most of the women were from Latin America (45.6% and Eastern Europe (30.7%; >60% of them had stable partners, did not use contraception and had had at least one pregnancy. The prevalence rates of HPV, Ct, Tv and Ng infections were 24.2%, 7.8%, 4.8% and 0%, respectively. In all, 43.2% of the positive women agreed to undergo a gynecological examination and accepted suitable treatment. Conclusions: This study shows an overall high prevalence of STIs in undocumented migrant women in Milan. The screening strategy based on counseling and urine testing contributed to the successfully high acceptability rate. More appropriate health services that adequately address all aspects of women’s health are required.

  6. AMPK in the central nervous system: physiological roles and pathological implications

    Directory of Open Access Journals (Sweden)

    Rosso P

    2016-01-01

    Full Text Available Pamela Rosso,1,2,* Marco Fioramonti,3,* Anna Fracassi,2 Martina Marangoni,4 Valentina Taglietti,5 Silvia Siteni,2,6 Marco Segatto5 1Institute of Cell Biology and Neurobiology, National Research Council (CNR, 2Department of Sciences, University of Rome “Roma Tre”, 3Laboratory of Translational Oncology, University Campus Bio-Medico of Rome, 4Medical Genetics Unit, University Hospital of Rome “Tor Vergata”, Rome, 5Department of Biosciences, University of Milan, Milan, 6Department of Experimental Oncology, Regina Elena National Cancer Institute, Rome, Italy *These authors contributed equally to this work Abstract: 5′ AMP-activated protein kinase (AMPK is considered the master metabolic regulator in all eukaryotes, as it maintains cellular energy homeostasis in a variety of tissues, including the brain. In humans, alterations in AMPK activity can lead to a wide spectrum of metabolic disorders. The relevance of this protein kinase in the pathogenesis of diabetes and metabolic syndrome is now well established. On the contrary, correlations between AMPK and brain physiopathology are still poorly characterized. The aim of this review is to summarize and discuss the current knowledge about the prospective involvement of AMPK in the onset and the progression of different neurological diseases. Keywords: AMPK, brain, neurodegeneration, stroke, tumor, autophagy

  7. Plant poisoning in domestic animals: epidemiological data from an Italian survey (2000-2011).

    Science.gov (United States)

    Caloni, F; Cortinovis, C; Rivolta, M; Alonge, S; Davanzo, F

    2013-06-01

    An Italian epidemiological study based on the human Poison Control Centre of Milan (Centro Antiveleni di Milano (CAV)) data related to domestic animal poisoning by exposure to plants, was carried out in collaboration with the Veterinary Toxicology Section of the University of Milan. It encompasses a 12-year period, from the beginning of 2000 to the end of 2011. Calls related to toxic plants accounted for 5.7 per cent of total inquiries (2150) received by CAV. The dog was the most commonly poisoned species (61.8 per cent of calls) followed by the cat (26 per cent). Little information was recorded for other species. Most exposures (73.8 per cent) resulted in mild to moderate clinical signs. The outcome was reported in only 53.7 per cent of cases, and fatal poisoning accounted for 10.6 per cent of these cases. Glycoside, alkaloid, oxalate, toxalbumin, saponin, terpene and terpenoid-containing plants were recorded and found to be responsible for intoxication. Cycas revoluta, Euphorbia pulcherrima, Hydrangea macrophylla, Nerium oleander, Rhododendron species and Prunus species were the plants most frequently involved. Epidemiological data from this Italian survey provide useful information on animal exposure to plants and confirm the importance of plants as causative agents of animal poisoning.

  8. Multifocal manifestation does not affect vascular invasion of hepatocellular carcinoma: implications for patient selection in liver transplantation.

    Science.gov (United States)

    Löhe, Florian; Angele, Martin K; Rentsch, Markus; Graeb, Christian; Gerbes, Alexander; Löhrs, Udo; Beuers, Ulrich; Jauch, Karl-Walter

    2007-01-01

    Liver transplantation (OLT) for hepatocellular carcinoma (HCC) improves patient survival when tumor size and number are limited according to the Milan criteria. However, the impact of tumor size vs. the number of lesions for tumor recurrence after OLT is unclear. Microvascular invasion appears to be a significant risk factor for tumor recurrence. Therefore, it was the aim of this study to investigate tumor differentiation and microvascular invasion in relation to tumor number and size and their impact on survival after transplantation. In 97 adult HCC patients who underwent OLT between June 1985 and December 2005 the incidence of microvascular invasion, tumor differentiation, and the number and size of tumor lesions were analyzed retrospectively. Their impact on survival was studied by multivariate analysis. Microvascular invasion was the only independent negative predictor of survival after OLT for HCC (p = 0.025). Tumor size > 5 cm was predictive for microvascular invasion (p = 0.007). In contrast, tumor number did not affect the incidence of microvascular invasion or cumulative survival. The size of the largest HCC lesion, but not the number of tumors, determined microvascular invasion, a predictor of the outcome following OLT for HCC. Thus, the number of HCC lesions should not be applied to patient selection prior to OLT. These data support the extension of the Milan criteria for the selection of HCC patients for OLT with regard to tumor number, but not tumor size.

  9. Pollution transport event in Italian Alps: Monitoring, measurement and analysis

    International Nuclear Information System (INIS)

    Marcazzan, G.M.; Maugeri, M.; Bonelli, P.

    1990-01-01

    The study of long range transport of aerosol pollution is a field of increasing interest. Within the framework of a program of aerosol characterization in urban areas and remote sites, a pollution transport event was identified through concentration analysis of some tracer elements in particulate matter. PIXE and PIGE code analyses of the concentrations of some elements of atmospheric particulate collected in Milan showed unusually high concentrations of S, Zn, V, Ni, and K in the period 30/6/87-2/7/87. After some days (3/7/87-5/7/87), very high concentrations of the same elements were measured also in the samples collected in a mountain station (Sestriere) situated 200 km west of Milan. The analysis of the anemological situation showed a systematic tendency of the flow to move slowly speed eastward in the whole Po Valley, suggesting the hypothesis of an event of long range pollution transport. The analysis of the daily maximum mixing depth and the calculation of back and forward trajectories supported this hypothesis

  10. [The experience of the EPM (Ergonomics of Posture and Movement) Research Unit in risk analysis and the prevention of work-related musculo-skeletal diseases (WMSDs)].

    Science.gov (United States)

    Occhipinti, E; Colombini, Daniela; Molteni, G

    2003-01-01

    The twenty-year experience of the "Ergonomics of Posture and Movement (epm)" Research Unit for prevention of work-related musculoskeletal disorders (WMSDs) is briefly summarized. The epm research unit is the outcome of an agreement between Milan University (Clinica del Lavoro Luigi Devoto), Milan Polytechnic, Don Gnocchi Foundation IRCCS (Bioengineering Centre) and the Regional Health Service (CEMOC of ICP Hospital). Early activities of epm (1985-1993) are first outlined: they are characterized by a wide range of laboratory studies allowing the development of original methods and criteria for on-site analysis of fixed postures and awkward movements and for ad hoc clinical examination of the musculoskeletal apparatus in working populations. Epm contributions are reviewed for the analysis of working activity involving manual load handling (adapted NIOSH method) and hospital patients (MAPO method) as well as for standardization of health surveillance protocols of spinal diseases. Updated contributions are reported on analysis and prevention of upper limb MSDs connected with upper limb repetitive movements (OCRA method). Finally epm's main collaborations with national and international Authorities are summarized as well as the major technical (health promotion) publications addressed to operators and workers, in different working situations, for prevention of musculoskeletal disorders due to biomechanical overload.

  11. Osteopathic manipulative treatment is effective on pain control associated to spinal cord injury.

    Science.gov (United States)

    Arienti, C; Daccò, S; Piccolo, I; Redaelli, T

    2011-04-01

    This study was designed as an experimental study (trial). To verify the effects of the association between conventional pharmacological treatment and osteopathic manipulative treatment (OMT) for chronic pain management in spinal cord injury (SCI). This study was carried out at Spinal Unit, Ospedale Niguarda Ca' Granda, Milan, Italy. Istituto Superiore di Osteopatia, Milan, Italy. We enrolled 47 patients with SCI, 26 with pain of both nociceptive and neuropathic origin, and 21 with pure neuropathic pain. In all, 33 patients had a complete spinal cord lesion (ASIA level A) and 14 had incomplete lesion (ASIA level B, C and D). The patients were subdivided in a pharmacological group (Ph), a pharmacological osteopathic (PhO) group and a osteopathic (Os) group. The verbal numeric scale (VNS) was used at various time intervals to evaluate treatment outcomes. Ph patients reached a 24% improvement in their pain perception, assessed by the VNS scale after 3 weeks of treatment, whereas Os patients reached a 16% improvement in their pain perception for the same weeks. Both treatments per se failed to induce further improvements at later time points. In contrast, the combination of the two approaches yielded a significantly better pain relief both in patients with nociceptive or pure neuropathic pain in the PhO group. Our results suggest the OMT is a feasible approach in patients in whom available drugs cannot be used. Moreover, a benefit can be expected by the association of OMT in patients treated according to existing pharmacological protocols.

  12. The mitochondrial genome, a growing interest inside an organelle

    Directory of Open Access Journals (Sweden)

    Marco Crimi

    2008-03-01

    Full Text Available Marco Crimi1, Roberta Rigolio21National Institute of Molecular Genetics (INGM, Functional Genomics Unit, Milan, Italy; 2Department of Neurosciences and Biomedical Technologies, University of Milan Bicocca, Monza, ItalyAbstract: Mitochondria are semi-autonomously reproductive organelles within eukaryotic cells carrying their own genetic material, called the mitochondrial genome (mtDNA. Until some years ago, mtDNA had primarily been used as a tool in population genetics. As scientists began associating mtDNA mutations with dozens of mysterious disorders, as well as the aging process and a variety of chronic degenerative diseases, it became increasingly evident that the information contained in this genome had substantial potential applications to improve human health. Today, mitochondria research covers a wide range of disciplines, including clinical medicine, biochemistry, genetics, molecular cell biology, bioinformatics, plant sciences and physiology. The present review intends to present a summary of the most exiting fields of the mitochondrial research bringing together several contributes in terms of original prospective and future applications.Keywords: mtDNA, heteroplasmy, molecular diagnostics, mitochondriopathies, nanogenomics

  13. Clinical and symptomatological reflections: the fascial system

    Directory of Open Access Journals (Sweden)

    Bordoni B

    2014-09-01

    Full Text Available Bruno Bordoni,1,2 Emiliano Zanier2,3 1Department of Cardiology, IRCCS S Maria Nascente, Don Carlo Gnocchi Foundation, Milan, Italy; 2CRESO Osteopathic Centre for Research and Studies, 3EdiAcademy, Milan, Italy Abstract: Every body structure is wrapped in connective tissue, or fascia, creating a structural continuity that gives form and function to every tissue and organ. Currently, there is still little information on the functions and interactions between the fascial continuum and the body system; unfortunately, in medical literature there are few texts explaining how fascial stasis or altered movement of the various connective layers can generate a clinical problem. Certainly, the fascia plays a significant role in conveying mechanical tension, in order to control an inflammatory environment. The fascial continuum is essential for transmitting muscle force, for correct motor coordination, and for preserving the organs in their site; the fascia is a vital instrument that enables the individual to communicate and live independently. This article considers what the literature offers on symptoms related to the fascial system, trying to connect the existing information on the continuity of the connective tissue and symptoms that are not always clearly defined. In our opinion, knowing and understanding this complex system of fascial layers is essential for the clinician and other health practitioners in finding the best treatment strategy for the patient. Keywords: fascia, osteopathic, low back pain, neck, pain

  14. Air pollution forecast in cities by an air pollution index highly correlated with meteorological variables

    International Nuclear Information System (INIS)

    Cogliani, E.

    2001-01-01

    There are many different air pollution indexes which represent the global urban air pollution situation. The daily index studied here is also highly correlated with meteorological variables and this index is capable of identifying those variables that significantly affect the air pollution. The index is connected with attention levels of NO 2 , CO and O 3 concentrations. The attention levels are fixed by a law proposed by the Italian Ministries of Health and Environment. The relation of that index with some meteorological variables is analysed by the linear multiple partial correlation statistical method. Florence, Milan and Vicence were selected to show the correlation among the air pollution index and the daily thermic excursion, the previous day's air pollution index and the wind speed. During the January-March period the correlation coefficient reaches 0.85 at Milan. The deterministic methods of forecasting air pollution concentrations show very high evaluation errors and are applied on limited areas around the observation stations, as opposed to the whole urban areas. The global air pollution, instead of the concentrations at specific observation stations, allows the evaluation of the level of the sanitary risk regarding the whole urban population. (Author)

  15. Disease-modifying drugs in Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Ghezzi L

    2013-12-01

    Full Text Available Laura Ghezzi, Elio Scarpini, Daniela Galimberti Neurology Unit, Department of Pathophysiology and Transplantation, University of Milan, Fondazione Cà Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy Abstract: Alzheimer's disease (AD is an age-dependent neurodegenerative disorder and the most common cause of dementia. The early stages of AD are characterized by short-term memory loss. Once the disease progresses, patients experience difficulties in sense of direction, oral communication, calculation, ability to learn, and cognitive thinking. The median duration of the disease is 10 years. The pathology is characterized by deposition of amyloid beta peptide (so-called senile plaques and tau protein in the form of neurofibrillary tangles. Currently, two classes of drugs are licensed by the European Medicines Agency for the treatment of AD, ie, acetylcholinesterase inhibitors for mild to moderate AD, and memantine, an N-methyl-D-aspartate receptor antagonist, for moderate and severe AD. Treatment with acetylcholinesterase inhibitors or memantine aims at slowing progression and controlling symptoms, whereas drugs under development are intended to modify the pathologic steps leading to AD. Herein, we review the clinical features, pharmacologic properties, and cost-effectiveness of the available acetylcholinesterase inhibitors and memantine, and focus on disease-modifying drugs aiming to interfere with the amyloid beta peptide, including vaccination, passive immunization, and tau deposition. Keywords: Alzheimer's disease, acetylcholinesterase inhibitors, memantine, disease-modifying drugs, diagnosis, treatment

  16. María Luisa: Delirios de vida y muerte

    Directory of Open Access Journals (Sweden)

    Juan José Jordán

    2015-01-01

    Full Text Available Esta propuesta consiste en enjuiciar a través de mi texto dramático María Luisa (Ediciones Unicornio, 2013 a María Luisa Milanés(1893-1919 como figura del Bayamo de la naciente República, que se convierte en figura indiscutible de las letras femeninas cubanas. Tomo como punto de partida su opacado perfil histórico-literario, resultado de un contexto sociocultural hostil, decidido a ignorarla.María Luisa es una invitación, también, para los entendidos en literatura al análisis de un incipiente y malogrado discurso narrativo y un más elaborado discurso lírico. Es una pretensión de rescatar a esta escritora en los‹‹ estudios de género››; que mi texto funcione como marco teórico para una profundización crítica, área que carece de un verdadero juicio literario milanesiano . Es un intento por enriquecer la bibliografía al respecto, con un enfoque sociocultural integrador, donde la proyección intragenérica predominante en la obra de María Luisa Milanés transite desde la historia cultural microsocial hacia el discurso femenino, también conformador de lo nacional.

  17. Prognostic Factors for Tumor Recurrence after a 12-Year, Single-Center Experience of Liver Transplantations in Patients with Hepatocellular Carcinoma

    Directory of Open Access Journals (Sweden)

    Matteo Cescon

    2010-01-01

    Full Text Available Background. Factors affecting outcomes after orthotopic liver transplantation (OLT for hepatocellular carcinoma (HCC have been extensively studied, but some of them have only recently been discovered or reassessed. Methods. We analyzed classical and more recently emerging variables with a hypothetical impact on recurrence-free survival (RFS in a single-center series of 283 patients transplanted for HCC between 1997 and 2009. Results. Five-year patient survival and RFS were 75% and 86%, respectively. Thirty-four (12% patients had HCC recurrence. Elevated preoperative alpha-fetoprotein (AFP levels, preoperative treatments of HCC, unfulfilled Milan and up-to-seven criteria at final histology, poor tumor differentiation, and tumor microvascular invasion negatively affected RFS by univariate analysis. Milan and up-to-seven criteria applied preoperatively, and the use of m-TOR inhibitors did not reach statistical significance. Cox's proportional hazard model showed that only elevated AFP levels (Odds Ratio=2.88; 95% C.I.=1.43–5.80; =.003, preoperative tumor treatments (Odds Ratio=4.84; 95% C.I.=1.42–16.42; =.01, and microvascular invasion (Odds Ratio=4.82; 95% C.I.=1.87–12.41; =.001 were predictors of lower RFS. Conclusions. Biological aggressiveness and preoperative tumor treatment, rather than traditional and expanded dimensional criteria, conditioned the outcomes in patients transplanted for HCC.

  18. Gesti convenzionali e arte mimica nell’Ottocento italiano

    Directory of Open Access Journals (Sweden)

    Noemi Massari

    2015-03-01

    Full Text Available The present essay aims at reviewing the issues and methodologies faced in my PhD research. The first step will be the analysis of the theoretical assumptions that underlie the emergence of ballet pantomime and the rediscovery of classical pantomime. The essay will proceed outlining the artistic and cultural landscapes of the two Italian cities examined, Milan and Naples, aiming at defining, from a didactic viewpoint, the teaching of pantomime in the two largest Italian academies, the Teatro alla Scala in Milan and the Teatro di San Carlo in Naples. The third step will be the recording of the few references to the mime art contained in the treaties and documents relating to the dance in Italy during the Nineteenth century (Carlo Blasis, Vincenzo Buonsignori, Giulio Pompeo Ferrario. These references will be compared to the major mime treatises for actors (Giovanni Emanuele Bideri, Antonio Morrocchesi, Angelo Canova, Alemanno Morelli and opera singers (Manuel Garcia, Fernando Pelzet, Leone Giraldoni, Enrico Serafino Torelli, Augusto Delle Sedie in order to analyze the development of gesture during the Nineteenth century and the different use that each interpreter did of the expressive mime.

  19. "Tools" for the Development of the Inspection Activity in Archaeological Sites

    Directory of Open Access Journals (Sweden)

    Susanna Bortolotto

    2015-05-01

    Full Text Available One of the acquisitions of contemporary conservation philosophy is precisely this: you don’t restore the image but the matter of the work; restoration is first and foremost the conservation of the work’s authenticity. The task of conservation is not returning to an impossible past but rather enabling the work to be handed down to the future. From this standpoint, in today’s conservation language we speak of conservation: guaranteeing through our efforts that the work entrusted to us will still be available for the future, for ourselves and the generations to come, eliminating or slowing down the causes of deterioration that endanger it so that it can be enjoyed and used. The project, "Milan Archaeology for Expo 2015. Towards a valorization of the archaeological heritage of the city", intends - respect to these theoretical and methodological - to develop processes of knowledge and planned conservation of urban archaeological areas with coordinated maintenance actions, promotion and communication of the different sites present in Milan historic centre. All this sites will be connected in a network system built for a larger project that it will increase the accessibility and enhancement.

  20. [Evaluation of the treatment with levodropropizine of respiratory diseases in children].

    Science.gov (United States)

    Fiocchi, A; Zuccotti, G V; Vignati, B; Pogliani, L; Sala, M; Riva, E

    1989-01-01

    Sometimes, antitussives can be a valid adjuvant to respiratory tract infections treatment. Although not always needed, this therapeutic support can be extremely useful in selected cases, and when patient is resident and monitored. In this line, the efficacy of a new peripheral antitussive, levodropropizine (Dompé farmaceutici, Milan), has been evaluated in 70 children inpatients of the Pediatric Department at san Paolo Hospital - Milan University - from September 1987 to May 1988. Thirty one male and 29 female children, aged 4 years and 6 months +/- 3 years and 5 months, suffering from various respiratory tract diseases were included in the study. Underlying diseases were represented by 21 acute bronchitis, 20 asthmatic attacks, 18 bronchopneumonia, 11 tracheitis, 6 acute episodes of chronic bronchitis, 2 hypoglottis laryngitis, 1 pertussis, 1 spontaneous pneumothorax. All parents gave their oral informed consent. The basic treatments were antibiotics in 44 patients associated or not with beta 2 agonists (31), theophylline (15), corticosteroids via aerosol (9) or parenterally (3), immunomodulators (2). Treatment with levodropropizine in the oral drops formulation at 2 mg pro kg a day was continued for 5 days and withdrawn according to the clinical evolution. Cough was registered by means of appropriate record forms given to the parents as well as with 120' tape recording whenever possible, i.e. 60 minutes before and 60 minutes after drug administration, on day one and 2. At treatment end, parents and investigator gave an antitussive efficacy judgement. Tolerability was evaluated as per clinical evolution and laboratory parameters.

  1. Barrio residencial de Gratosoglio, Milán

    Directory of Open Access Journals (Sweden)

    Giannini, Sandro

    1967-04-01

    Full Text Available The group of 23 buildings in the residential zone of Gratosoglio, which provide space for 1,000 dwellings, has been built by the firm «Fintech Italcamus». This Italian firms applies in Italy the «Raymond Camus» system, which is a positive aid to heavy prefabrication in housing projects. The above group of buildings constitute part of the General Building Scheme so successfully initiated by the Autonomous Building Institute of the Province of Milan, with the purpose of helping to overcome the extensive lack of housing in the Milan region.El grupo de edificios levantado en el Barrio Residencial de Gratosoglio, Milán (23, con un total de 1.000 viviendas, ha sido construido por la firma «Fintech Italcamus», Sociedad italiana que aplica en Italia el sistema «Raymond Camus» y constituye una aportación positiva de la prefabricación pesada a la edificación residencial. Este conjunto forma parte del Plan General de edificación, emprendido con tanto éxito como acierto por el Instituto Autónomo de la Vivienda de la Provincia de Milán, para solucionar los problemas que la gigantesca presión demográfica planteaba en dicha provincia.

  2. Super and ferric: the first HL-LHC component is ready

    CERN Multimedia

    Antonella Del Rosso

    2016-01-01

    Although the actual installation phase in the tunnel will only start in 2024, the first magnet – a sextupole – of the High-Luminosity LHC (HL-LHC) is ready and working according to specifications. This first component is also rather unique as, unlike the superconducting magnets currently used in the LHC, it relies on a “superferric” heart.   An expert in the LASA Laboratory (INFN Milan, Italy) works on assembling the first sextupole corrector of the HL-LHC. (Image: INFN Milan) Although the name might sound completely unfamiliar, superferric magnets were first proposed in the 1980s as a possible solution for high-energy colliders. However, many technical problems had to be overcome before the use of superferric magnets could become a reality. In its final configuration, the HL-LHC will have 36 superferric corrector magnets, of which 4 will be quadrupoles, 8 sextupoles and 24 higher order magnets. In superferric (or “iron-dominated”) magne...

  3. Intestinal Parasites of Owned Dogs and Cats from Metropolitan and Micropolitan Areas: Prevalence, Zoonotic Risks, and Pet Owner Awareness in Northern Italy

    Science.gov (United States)

    Zanzani, Sergio Aurelio; Gazzonis, Alessia Libera; Berrilli, Federica

    2014-01-01

    Intestinal parasites of dogs and cats are cosmopolitan pathogens with zoonotic potential for humans. Our investigation considered their diffusion in dogs and cats from northern Italy areas, specifically the metropolitan area of Milan and two micropolitan areas of neighboring provinces. It included the study of the level of awareness in pet owners of the zoonotic potential from these parasites. A total of 409 fresh fecal samples were collected from household dogs and cats for copromicroscopic analysis and detection of Giardia duodenalis coproantigens. The assemblages of Giardia were also identified. A questionnaire about intestinal parasites biology and zoonotic potential was submitted to 185 pet owners. The overall prevalence of intestinal parasites resulted higher in cats (47.37%−60.42%) and dogs (57.41%−43.02%) from micropolitan areas than that from the metropolis of Milan (dogs: P = 28.16%; cats: P = 32.58 %). The zoonotic parasites infecting pets under investigation were T. canis and T. cati, T. vulpis, Ancylostomatidae, and G. duodenalis assemblage A. Only 49.19% of pet owners showed to be aware of the risks for human health from canine and feline intestinal parasites. Parasitological results in pets and awareness determination in their owners clearly highlight how the role of veterinarians is important in indicating correct and widespread behaviors to reduce risks of infection for pets and humans in urban areas. PMID:24883320

  4. Development of hepatocellular carcinomas in patients with absence of tumors on a prior ultrasound examination

    International Nuclear Information System (INIS)

    Kim, Kyung Ah; Kim, Myeong-Jin; Choi, Jin-Young; Chung, Yong Eun

    2012-01-01

    Background: To evaluate hepatocellular carcinoma (HCC) that developed in patients with no evidence of a tumor during a prior ultrasound (US) performed within 1 year of the diagnosis. Methods: We retrospectively analyzed data for 100 consecutive patients with liver cirrhosis who had undergone US within 1 year prior to HCC diagnosis and who showed no liver lesions on the previous US. Size and T stage of HCC were assessed as well as whether patients met surgical criteria for liver transplantation as HCC treatment [Milan or University of California at San Francisco (UCSF) criteria]. Results: The mean interval between the negative and diagnostic scans was 5 months, 13 days. HCC presented as a single nodule in 69 patients (size, 0.8–8.0 cm), as two or more nodules in 18 patients, and as the diffuse form of HCC in 13 patients. HCC presented as a small tumor (<3 cm) in 48 patients. T stages were: T1 in 26 patients, T2 in 45, T3 in 18, and T4 in 11. The Milan criteria were met in 79 patients. Eighty-five patients fulfilled the UCSF. Conclusion: Patients may present with advanced HCC, even if sonographic findings were negative within 1 year prior to diagnosis.

  5. [Sustainability and hygiene of building: future perspectives].

    Science.gov (United States)

    Capolongo, Stefano; Buffoli, Maddalena; Oppio, Alessandra; Petronio, Maria Grazia

    2014-01-01

    Multiple factors influence individuals' health status. Their impact is difficult to quantify as it is their interaction. Aim of the current work is to develop guidelines to support designers to promote health in the residential environment and to apply them through an evaluation system to certify the level of health performance. Politecnico di Milano, in collaboration with the Local Health Authorities of Milan and Empoli through analysis of needs performance and numerous multidisciplinary meetings, has produced a design guide (Healthy Design Guide - HeDe) and an evaluation system to certify the level of health performance. This system was tested on the Milan metropolitan area. The experiment was carried out on a sample of 30 private residences, with an overall floor area ranging between 90 and 150 square meters, new or recently renovated. The tool works but at the same time it also shows that too often design choices are made for aesthetic or economic reasons rather than a real need for health and wellness. It is becoming increasingly important to strengthen synergies and multidisciplinary collaborations to achieve shared performance indications and to make a systematic review of the regulatory tools to protect public health.

  6. Genetic diversity, QoI fungicide resistance, and mating type distribution of Cercospora sojina-Implications for the disease dynamics of frogeye leaf spot on soybean.

    Science.gov (United States)

    Shrestha, Sandesh Kumar; Cochran, Alicia; Mengistu, Alemu; Lamour, Kurt; Castro-Rocha, Arturo; Young-Kelly, Heather

    2017-01-01

    Frogeye leaf spot (FLS), caused by Cercospora sojina, causes significant damage to soybean in the U.S. One control strategy is the use of quinone outside inhibitor (QoI) fungicides. QoI resistant isolates were first reported in Tennessee (TN) in 2010. To investigate the disease dynamics of C. sojina, we collected 437 C. sojina isolates in 2015 from Jackson and Milan, TN and used 40 historical isolates collected from 2006-2009 from TN and ten additional states for comparison. A subset of 186 isolates, including historical isolates, were genotyped for 49 single nucleotide polymorphism (SNP) markers and the QoI resistance locus, revealing 35 unique genotypes. The genotypes clustered into three groups with two groups containing only sensitive isolates and the remaining group containing all resistant isolates and a dominant clonal lineage of 130 isolates. All 477 C. sojina isolates were genotyped for the QoI locus revealing 344 resistant and 133 sensitive isolates. All isolates collected prior to 2015 were QoI sensitive. Both mating type alleles (MAT1-1-1 and MAT1-2) were found in Jackson and Milan, TN and recovered from single lesions suggesting sexual recombination may play a role in the epidemiology of field populations. Analysis of C. sojina isolates using SNP markers proved useful to investigate population diversity and to elaborate on diversity as it relates to QoI resistance and mating type.

  7. Pollution transport event in Italian Alps: Monitoring, measurement and analysis; Studio di un evento di trasporto di inquinanti in una stazione alpina

    Energy Technology Data Exchange (ETDEWEB)

    Marcazzan, G.M.; Maugeri, M.; Bonelli, P.

    1990-12-31

    The study of long range transport of aerosol pollution is a field of increasing interest. Within the framework of a program of aerosol characterization in urban areas and remote sites, a pollution transport event was identified through concentration analysis of some tracer elements in particulate matter. PIXE and PIGE code analyses of the concentrations of some elements of atmospheric particulate collected in Milan showed unusually high concentrations of S, Zn, V, Ni, and K in the period 30/6/87-2/7/87. After some days (3/7/87-5/7/87), very high concentrations of the same elements were measured also in the samples collected in a mountain station (Sestriere) situated 200 km west of Milan. The analysis of the anemological situation showed a systematic tendency of the flow to move slowly speed eastward in the whole Po Valley, suggesting the hypothesis of an event of long range pollution transport. The analysis of the daily maximum mixing depth and the calculation of back and forward trajectories supported this hypothesis.

  8. Oral use of Streptococcus salivarius K12 in children with secretory otitis media: preliminary results of a pilot, uncontrolled study

    Directory of Open Access Journals (Sweden)

    Di Pierro F

    2015-09-01

    Full Text Available Francesco Di Pierro,1 Daniele Di Pasquale,2 Maurizio Di Cicco2 1Velleja Research, Milan, Italy; 2ORL Department, Ospedale Maggiore Policlinico Ca’ Grande IRCCS, Milan, Italy Abstract: Secretory otitis media (SOM remains a common disease among children. Although its cause is not yet perfectly established, the pathology, often a sequel of acute otitis media (AOM, is mainly characterized by persistent fluid in the middle ear cavity. Twenty-two children with a diagnosis of SOM were treated daily for 90 days with an oral formulation containing the oral probiotic Streptococcus salivarius K12 (Bactoblis®. After treatment, the children were evaluated for AOM episodes and subjected to tone audiometry, tympanometry, endonasal endoscopy, otoscopy, and tonsillar examination. Subject compliance and probiotic tolerability and side effects have also been evaluated. Our results indicate a good safety profile, a substantial reduction of AOM episodes, and a positive outcome from the treatment for all of the clinical outcomes tested. We conclude that strain K12 may have a role in reducing the occurrence and/or severity of SOM in children. From our perspective, this study constitutes a starting point toward the organization of a more extensive placebo-controlled study aimed at critically appraising our preliminary observations. Keywords: BLIS K12, Bactoblis®, acute otitis media, exudative otitis media

  9. Personalized treatment in advanced ALK-positive non-small cell lung cancer: from bench to clinical practice

    Directory of Open Access Journals (Sweden)

    Passaro A

    2016-10-01

    Full Text Available Antonio Passaro,1 Chiara Lazzari,1,2 Niki Karachaliou,3 Gianluca Spitaleri,1 Alessia Pochesci,1 Chiara Catania,1 Rafael Rosell,4 Filippo de Marinis1 1Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy; 2Department of Medical Oncology, Division of Experimental Medicine, San Raffaele Scientific Institute, Milan, Italy; 3Oncology Institute Dr Rosell, Quiron-Dexeus University Hospital, Barcelona, Spain; 4Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain Abstract: The discovery of anaplastic lymphoma kinase (ALK gene rearrangements and the development of tyrosine kinase inhibitors (TKI that target them have achieved unprecedented success in the management of patients with ALK-positive non-small cell lung cancer (NSCLC. Despite the high efficacy of crizotinib, the first oral ALK TKI approved for the treatment of ALK-positive NSCLC, almost all patients inevitably develop acquired resistance, showing disease progression in the brain or in other parenchymal sites. Second- or third-generation ALK TKIs have shown to be active in crizotinib-pretreated or crizotinib-naïve ALK-positive patients, even in those with brain metastases. In this review, the current knowledge regarding ALK-positive NSCLC, focusing on the biology of the disease and the available therapeutic options are discussed. Keywords: ALK, NSCLC, crizotinib, ceritinib, alectinib, brigatinib, lorlatinib, brain metastases

  10. The current role of sublingual immunotherapy in the treatment of allergic rhinitis in adults and children

    Directory of Open Access Journals (Sweden)

    Simonetta Masieri

    2011-02-01

    Full Text Available Cristoforo Incorvaia1, Simonetta Masieri2, Silvia Scurati3, Silvia Soffia3, Paola Puccinelli3, Franco Frati31Allergy/Pulmonary rehabilitation, Istituti Clinici di Perfezionamento, Milan, Italy; 2ENT Clinic, University La Sapienza, Rome, Italy; 3Medical and Scientific Department, Stallergenes, Milan, ItalyAbstract: Allergic rhinitis is a very common disease affecting about 20% of people. It may be treated by allergen avoidance when possible, by antiallergic drugs such as antihistamines and topical corticosteroids, and by allergen-specific immunotherapy. The latter is the only treatment able to act on the causes and not only on the symptoms of respiratory allergy and is able to maintain its efficacy even after stopping, provided an adequate duration of treatment of 3–5 years is ensured. Sublingual immunotherapy (SLIT was introduced in the 1990s as a possible solution to the problem of adverse systemic reactions to subcutaneous immunotherapy and has been demonstrated by more than 50 trials and globally evaluated thus far by five meta-analyses as an effective and safe treatment for allergic rhinitis. Life-threatening reactions are extremely rare. However, it is important to note that clinical efficacy occurs only if SLIT meets its needs, ie, sufficiently high doses are regularly administered for at least 3 consecutive years. This is often overlooked in the current practice and may prevent the same success reported by trials from being achieved.Keywords: allergic rhinitis, sublingual immunotherapy, efficacy, safety, compliance, meta-analysis 

  11. Decisions and involvement of cancer patient survivors: a moral imperative

    Directory of Open Access Journals (Sweden)

    Pravettoni G

    2016-12-01

    Full Text Available Gabriella Pravettoni,1,2 Ilaria Cutica,1,2 Simona Righetti,1 Ketti Mazzocco1,2 1Department of Oncology and Hematology, University of Milan, 2Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology, Milan, Italy Purpose: The aim of this study was to review the experiences of direct involvement in patient survivorship for treatment and research. Methods: This is a narrative-focused review of the following two recent experiences of patient involvement: the Chordoma Foundation and the Triple Negative Breast Cancer Foundation. Results: These two examples represent concrete experiences that patients have built to favor a real involvement in the care and treatment of tumors. These experiences are profoundly modifying how cancer research is conducted and draw attention to the psychosocial dimensions of health care. Conclusion: These examples represent the new scenario in which modern medicine faces completely new challenges, copes with new needs, and cooperates with new health care professionals. Implications: Involving patients in a new perspective raises practical and ethical challenges for organizations to work together, for health providers to be professionally skilled and for the government to promote safeguarding policies. Keywords: patient empowerment, patients’ association, empowerment, skills, codesign ­techniques, cancer

  12. [Sensitivity, precision and resolution of the optical microscope in the study of environmental pollution by asbestos fibers].

    Science.gov (United States)

    Maddalon, G; Patroni, M; Trimarchi, R; Clerici, C; Occella, E

    1991-01-01

    The authors comment on the methods and equipment used in two Italian laboratories for sampling and microscopic phase contrast analysis of asbestos and other respirable fibres in the air of the general environment, i.e., the Dust Analysis Laboratory, Industrial Hygiene and Toxicology Department of the Institute of Occupational Health (Clinica del Lavoro), University of Milan and the Technical Microscopy Laboratory, Ground Resources and Land Control (Georisorse e Territorio) Department of Turin Polytechnic, which use identical methods. Airborne dust samples are taken with personal samplers, 1 l/min air flow (sample duration 4-8 h), filtering air on 25 mm diameter, 0.8 micropore cellulose filters (about 300 mm total net surface of dust deposit). The following equipment is used for counting and analysis of fibres: a) Clinica del Lavoro, Milan: Polyvar Reichert-Jung microscope, 500 magnitudes, Zernike positive phase contrast; numerical counting on 100 whole ocular fields, equal to 6.38% of the total net surface of dust deposit on the membrane; b) Turin Polytechnic: Leitz Ortholux microscope, 500 magnitudes, Heine and Zernike phase contrast with mean standard contrast; numerical counting on square grid, with explored surface total equal to 1.68% of the total net surface of dust deposit on the membrane. Measurements performed: Clinica del Lavoro, Milan: 2,980 since 1960; Turin Polytechnic: 875 since 1965. The sensitivity of the methods for counting airborne fibres is discussed, concluding that the methods used by the two laboratories have a sensitivity between 0.05 and 1.6 fibre/litre of air, according to the overall dustiness of the environment under study. Analysis of the accuracy of the optic determinations, based on the repeated counts, shows a repeatability of 0.4 (40%) within 95% confidence limits. A resolution power of 0.35 microns is reported; however, the possibility exists (and is normally achieved in analytical practice in both laboratories) of identifying and

  13. Development and psychometric testing of a breast cancer patient-profiling questionnaire

    Directory of Open Access Journals (Sweden)

    Gorini A

    2015-06-01

    Full Text Available Alessandra Gorini,1,2 Ketti Mazzocco,1,2 Sara Gandini,2 Elisabetta Munzone,2 Gordon McVie,2 Gabriella Pravettoni1,2 1Department of Health Science, University of Milan, Milan, Italy; 2European Institute of Oncology, Milan, Italy Introduction: The advent of “personalized medicine” has been driven by technological advances in genomics. Concentration at the subcellular level of a patient's cancer cells has meant inevitably that the “person” has been overlooked. For this reason, we think there is an urgent need to develop a truly personalized approach focusing on each patient as an individual, assessing his/her unique mental dimensions and tailoring interventions to his/her individual needs and preferences. The aim of this study was to develop and test the psychometric properties of the ALGA-Breast Cancer (ALGA-BC, a new multidimensional questionnaire that assesses the breast cancer patient's physical and mental characteristics in order to provide physicians, prior to the consultation, with a patient's profile that is supposed to facilitate subsequent communication, interaction, and information delivery between the doctor and the patient. Methods: The specific validation processes used were: content and face validity, construct validity using factor analysis, reliability and internal consistency using test–retest reliability, and Cronbach's alpha correlation coefficient. The exploratory analysis included 100 primary breast cancer patients and 730 healthy subjects. Results: The exploratory factor analysis revealed eight key factors: global self-rated health, perceived physical health, anxiety, self-efficacy, cognitive closure, memory, body image, and sexual life. Test–retest reliability and internal consistency were good. Comparing patients with a sample of healthy subjects, we also observed a general ability of the ALGA-BC questionnaire to discriminate between the two. Conclusion: The ALGA-BC questionnaire with 29 items is a valid

  14. A novel prognostic nomogram accurately predicts hepatocellular carcinoma recurrence after liver transplantation: analysis of 865 consecutive liver transplant recipients.

    Science.gov (United States)

    Agopian, Vatche G; Harlander-Locke, Michael; Zarrinpar, Ali; Kaldas, Fady M; Farmer, Douglas G; Yersiz, Hasan; Finn, Richard S; Tong, Myron; Hiatt, Jonathan R; Busuttil, Ronald W

    2015-04-01

    Although radiologic size criteria (Milan/University of California, San Francisco [UCSF]) have led to improved outcomes after liver transplantation (LT) for hepatocellular carcinoma (HCC), recurrence remains a significant challenge. We analyzed our 30-year experience with LT for HCC to identify predictors of recurrence. A novel clinicopathologic risk score and prognostic nomogram predicting post-transplant HCC recurrence was developed from a multivariate competing-risk Cox regression analysis of 865 LT recipients with HCC between 1984 and 2013. Overall patient and recurrence-free survivals were 83%, 68%, 60% and 79%, 63%, and 56% at 1-, 3-, and 5-years, respectively. Hepatocellular carcinoma recurred in 117 recipients, with a median time to recurrence of 15 months, involving the lungs (59%), abdomen/pelvis (38%), liver (35%), bone (28%), pleura/mediastinum (12%), and brain (5%). Multivariate predictors of recurrence included tumor grade/differentiation (G4/poor diff hazard ratio [HR] 8.86; G2-3/mod-poor diff HR 2.56), macrovascular (HR 7.82) and microvascular (HR 2.42) invasion, nondownstaged tumors outside Milan criteria (HR 3.02), nonincidental tumors with radiographic maximum diameter ≥ 5 cm (HR 2.71) and <5 cm (HR 1.55), and pretransplant neutrophil-to-lymphocyte ratio (HR 1.77 per log unit), maximum alpha fetoprotein (HR 1.21 per log unit), and total cholesterol (HR 1.14 per SD). A pretransplantation model incorporating only known radiographic and laboratory parameters had improved accuracy in predicting HCC recurrence (C statistic 0.79) compared with both Milan (C statistic 0.64) and UCSF (C statistic 0.64) criteria alone. A novel clinicopathologic prognostic nomogram included explant pathology and had an excellent ability to predict post-transplant recurrence (C statistic 0.85). In the largest single-institution experience with LT for HCC, excellent long-term survival was achieved. Incorporation of routine pretransplantation biomarkers to existing

  15. Is there a standard for surgical therapy of hepatocellular carcinoma in healthy and cirrhotic liver? A comparison of eight guidelines.

    Science.gov (United States)

    Manzini, Giulia; Henne-Bruns, Doris; Porzsolt, Franz; Kremer, Michael

    2017-01-01

    Liver resection (LR) and transplantation are the most reliable treatments for hepatocellular carcinoma (HCC). Aim was to compare different guidelines regarding indication for resection and transplantation because of HCC with and without underlying cirrhosis. We compared the following guidelines published after 1 January 2010: American (American Association for the Study of Liver Diseases (AASLD)), Spanish (Sociedad Espanola de Oncologia Medica (SEOM)), European (European Association for the study of liver-European Organization for Research and Treatment of Cancer (EASL-EORTC) and European Society for Medical Oncology-European Society of Digestive Oncology (ESMO-ESDO)), Asian (Asian Pacific Association for the Study of Liver (APASL)), Japanese (Japan Society of Hepatology (JSH)), Italian (Associazione Italiana Oncologia Medica (AIOM)) and German (S3) guidelines. All guidelines recommend resection as therapy of choice in healthy liver. Guidelines based on the Barcelona Clinic Liver Cancer staging system recommend resection for single HCC<2 cm and Child-Pugh A cirrhosis and for HCC≤5 cm with normal bilirubin and portal pressure, whereas transplantation is recommended for multiple tumours between Milan criteria and for single tumours ≤5 cm and advanced liver dysfunction. Patients with HCC and Child-Pugh C cirrhosis are not candidates for transplantation. JSH guidelines recommend LR for patients with Child-Pugh A/B with HCC without tumour size restriction; APASL guidelines in general exclude patients with Child-Pugh A from transplantation. In patients with Child-Pugh B, transplantation is the second-line therapy, if resection is not possible for patients within Milan criteria. German and Italian guidelines recommend transplantation for all patients within Milan criteria. Whereas resection is the standard therapy of HCC in healthy liver, a standard regarding the indication for LR and transplantation for HCC in cirrhotic liver does not exist, although nearly all

  16. The POLIMI forecasting chain for real time flood and drought predictions

    Science.gov (United States)

    Ceppi, Alessandro; Ravazzani, Giovanni; Corbari, Chiara; Mancini, Marco

    2016-04-01

    Nowadays coupling meteorological and hydrological models is recognized by scientific community as a necessary way to forecast extreme hydrological phenomena, in order to activate useful mitigation measurements and alert systems in advance. The development and implementation of a real-time forecasting chain with a hydro-meteorological operational alert procedure for flood and drought events is presented in this study. Different weather models are used to build the POLIMI operative chain: the probabilistic COSMO-LEPS model with 16 ensembles developed by ARPA-Emilia Romagna, the deterministic Bolam and Moloch models, developed by the Italian ISAC-CNR, and nine further simulations obtained by different runs of the WRF-ARW (3), WRF-NMM (2), ETA2012 (1) and the GFS (3), provided by the private Epson Meteo Center and Terraria companies. All the meteorological runs are then implemented with the rainfall-runoff physically-based distributed FEST-WB model, developed at Politecnico di Milano to obtain a multi-model approach system with hydrological ensemble forecasts in different areas of study over the Italian country. As far as concerning drought predictions, three test-beds are monitored: two in maize fields, one in the Puglia region (South of Italy), and another in the Po Valley area, (northern Italy), and one in a golf course in Milan city. The hydrological model was here calibrated and validated against measurements of latent heat flux and soil moisture acquired by an eddy-covariance station, TDR probes and remote sensing images. Regarding flood forecasts, two test-sites are chosen: the first one is the urban area northern Milan where three catchments (the Seveso, Olona, and Lambro River basins) are used to show how early warning systems are an effective complement to structural measures for flood control in Milan city which flooded frequently in the last 25 years, while the second test-site is the Idro Lake, located between the Lombardy and Trentino region where the

  17. «GETTARE PONTI DA UNA LINGUA ALL’ALTRA». ITALIANO L2 ALLA SCUOLA GERMANICA ISTITUTO GIULIA DI MILANO (1925-1935

    Directory of Open Access Journals (Sweden)

    Paola Spazzali

    2017-03-01

    Full Text Available Il presente contributo si sofferma sulle condizioni dell’insegnamento dell’italiano alle elementari di una scuola tedesca di Milano, l’Istituto Giulia, a cavallo degli anni Trenta del Novecento. La presenza di un’elevata ed eccezionale percentuale di italofoni accanto ai madrelingua tedeschi creò classi linguisticamente non omogenee, un problema cui si fece fronte con aggiustamenti di orario, reclutamento di maestre prima bilingui poi italiane, e l’elaborazione di un metodo innovativo da parte di Sr. Maria Hildegara Heinz, maestra tedesca in possesso di diploma magistrale sia tedesco sia italiano. Partendo da un approccio positivo al bilinguismo, visto come un fattore di agevolazione dell’apprendimento e non come ostacolo, Sr. Hildegara elaborò per l’apprendimento della lettura e della scrittura un metodo contrastivo e realizzò un’unificazione della didattica che riguardava fonetica, morfologia, lessico e contenuti culturali. Descritto in una relazione che Sr. Hildegara presentò a un convegno nel 1929, il metodo viene qui contestualizzato, confrontato con le scelte didattiche della maestra dell’altra scuola tedesca a Milano, e proposto in traduzione. «Building bridges between languages».  Italian L2 at the “Scuola Germanica Istituto Giulia” in Milan (1925-1935 This paper focuses on the teaching of Italian in the primary classes of a German school in Milan, the Giulia Institute, in the 1930s. The presence of an exceptional proportion of Italian speakers with German native speakers created classes that were not linguistically homogeneous, a problem faced by making time adjustments, the recruitment of bilingual teachers and later Italian ones, and the development of an innovative method by Sister Maria Hildegara Heinz, a German teacher with both German and Italian teaching diplomas. Starting from a positive attitude towards bilingualism, seen as a factor facilitating learning and not as an obstacle, Sister Hildegara

  18. Editorial

    Directory of Open Access Journals (Sweden)

    B. Rossaro

    2015-08-01

    Full Text Available The Journal of Entomological and Acarological Research (JEAR, formerly the Bollettino di Zoologia Agraria e di Bachicoltura of the Institute of Entomology of the University of Milan, was founded in 1928 by Remo Grandori (1928-1955. Prof. Grandori became the first Director of the journal, followed by his wife Luigia Grandori (1956-1957, Minos Martelli (1958-1985 and Luciano Süss (1986-2011. In 2012, the Editor, the Department of Agri-food Systems Protection (DiPSA - University of Milan, come to the decision to move from the paper version to the online open access version of JEAR, with the aim to reach all researchers in the field with a restyled editorial, and with Giuseppe Carlo Lozzia as Editor in Chief (2012-2014. Thanks to the contributions of prestigious scientists and young researchers from all over the world, the Journal published many papers, which were downloaded in numerous countries across the world. Recently, the new Editor, the Department of Food Environmental and Nutritional Sciences - University of Milan, named me as Editor-in-Chief and I happily accepted the invitation with the objective to give new energy to the JEAR through the publication of more and more research papers of recognized scientific quality. The Journal will maintain its actual structure with four subject areas steered by internationally recognized Section Editors, who are now supported by a new and larger Editorial Board. The JEAR publishes papers on systematics, geographical speciation and evolution, aquatic and terrestrial entomology, ecological system dynamics, phenology and modelling for integrated pest control, agricultural and stored product pests, urban veterinary and forensic entomology, plant insect interaction and ecosystems, biological control and agro-ecology, and all other subjects related to the four subject areas. I hope the journal will continue to receive the attention of the researchers, in particular our younger colleagues in whose hands is

  19. Polilinguismo nella scrittura murale urbana: Note sulla lingua spagnola

    Directory of Open Access Journals (Sweden)

    ELena Landone

    2016-01-01

    Full Text Available Abstract – In this paper I focus on the polylinguistic and polycultural landscape of Milan on the theoretical basis of daily life studies, the sociolinguistics of globalization, and intercultural pragmatics. The relevance of this field is determined by the need for urban anthropology to semiotize the urban spaces as an interpretative bridge between the microsystem (the individual level and the macrosystem (the social level. More concretely, I investigate the presence of the Spanish language in the superdiversity of Milan and, methodologically, I collect ethnographically and interpret qualitatively a corpus of 700 daily life texts of various types of street writing. The results show the significant presence of Spanish in the urban landscape and a high level of hybridism which is, nevertheless, totally functional in communication. I also detect the emergence of linguistic, pragmatic and intercultural awareness in the writers. Finally, with some precautions, I confirm the scientific potential of the daily life documents to investigate complex urban dynamics.Resumen – El tema de este estudio es el panorama polilingüe y policultural de Milán y se plantea a partir de las bases teóricas de los everyday life studies, de la sociolingüistica de la globalización y de la pragmática intercultural. La relevancia del estudio descansa en la necesidad de la antropología urbana de elaborar una interpretación semiótica de los espacios urbanos, puesto que pueden constituir un puente interpretativo entre el microsistema (individuo y el macrosistema (sociedad. Concretamente, el objetivo es investigar el papel del idioma español en la supediversidad milanesa; la metodología es de etnografía urbana con la formación e interpretación cualitativa de un corpus fotográfico de setecientos textos cotidianos de escritura callejera (pintadas, avisos, grafiti, ecc.. Los datos relevan una presencia significativa del español en el landscape milanés, con un

  20. A high-performance network for a distributed-control system

    Science.gov (United States)

    Cuttone, G.; Aghion, F.; Giove, D.

    1989-04-01

    Local area networks play a central rule in modern distributed-control systems for accelerators. For a superconducting cyclotron under construction at the University of Milan, an optical Ethernet network has been implemented for the interconnection of multicomputer-based stations. Controller boards, with VLSI protocol chips, have been used. The higher levels of the ISO OSI model have been implemented to suit real-time control requirements. The experimental setup for measuring the data throughput between stations will be described. The effect of memory-to-memory data transfer with respect to the packet size has been studied for packets ranging from 200 bytes to 10 Kbytes. Results, showing the data throughput to range from 0.2 to 1.1 Mbit/s, will be discussed.

  1. A high-performance network for a distributed-control system

    International Nuclear Information System (INIS)

    Cuttone, G.; Aghion, F.; Giove, D.

    1989-01-01

    Local area networks play a central rule in modern distributed-control systems for accelerators. For a superconducting cyclotron under construction at the University of Milan, an optical Ethernet network has been implemented for the interconnection of multicomputer-based stations. Controller boards, with VLSI protocol chips, have been used. The higher levels of the ISO OSI model have been implemented to suit real-time control requirements. The experimental setup for measuring the data throughput between stations will be described. The effect of memory-to-memory data transfer with respect to the packet size has been studied for packets ranging from 200 bytes to 10 Kbytes. Results, showing the data throughput to range from 0.2 to 1.1 Mbit/s, will be discussed. (orig.)

  2. Exploiting CReP for Knowledge Retrieval and Use in Complex Domains

    Science.gov (United States)

    Manenti, Lorenza; Sartori, Fabio

    Case Based Reasoning (CBR) is a Knowledge Management approach that consists in the development of decision support systems where problem are solved by analogy with similar problem solved in the past. In this way, the system supports users in finding solutions without starting from scratch. CBR has become a very important research topic in Artificial Intelligence, with the definition of methodologies and architectural patterns for supporting developers in the design and implementation of case-based systems. The paper presents one of this frameworks, namely CReP, an on-going research project of the Artificial Intelligence Laboratory (L.Int.Ar.) of University of Milan-Bicocca, focusing on the integration between CBR paradigm and metadata approach to obtain domain-independent case structure and retrieval algorithm definition.

  3. Treatment of malignant polyps.

    Science.gov (United States)

    Spinelli, P; Pizzetti, P; Sala, P; Andreola, S; Bertario, L

    1995-01-01

    From 1975 to 1993, at the Division of Diagnostics and Endoscopic Surgery of the Istituto Nazionale Tumori in Milan, 191 malignant adenomas of colon-rectum have been endoscopically removed. On the basis of histopathologic criteria, endoscopic treatment has been judged adequate in 102 cases (53%), not adequate in 44 (23%), doubtfully adequate in 45 (24%). In 84 patients (44%) endoscopic polypectomy has been followed by surgical resection of the involved intestinal tract, 107 patients (56%) have been treated only by endoscopy. Results have been evaluated on the basis of surgical specimen, clinical follow-up and survival, showing that criteria we have adopted for the adequacy of the endoscopic treatment have a high negative predictive value (96%) and a low positive predictive value (32%). Actuarial survival of patients treated only endoscopically is 97% at 5 years and 95% at 10 years.

  4. Training guidelines in non-destructive testing techniques

    International Nuclear Information System (INIS)

    1991-10-01

    Non-destructive testing methods (NDT), by their very nature, allow components to be fully examined for properties or flaws without interfering with their usefulness. This grouping of inspection methods has grown from a handful of primitive techniques practised by artists to a widely known discipline which is an essential part of quality control, largely as a result of the standards demanded by the nuclear and aerospace industries. Recognizing the need for an international publication of NDT training syllabi, the IAEA Consultants Meeting on ''Qualification and Certification of NDT Personnel'' (Milan, 20-21 May 1986), recommended that the Agency publish the guidelines developed by Regional Working Group of the Latin America and Caribbean project. It was first issued in English in 1987 and has now been re-edited in English and Spanish and enlarged by the addition of programmes for other techniques

  5. The canceled marbles: limekilns in Gortys

    Directory of Open Access Journals (Sweden)

    Claudia Lambrugo

    2012-01-01

    Full Text Available The limekiln which is the subject of this paper was found during the last excavation in Gortys (2010, conducted by the University of Milan in the so called “Terme Milano”, south of the Pretorio. The little limekiln, which probably dates between the end of the 6th century A.D. and the beginning of the 7th century A.D., was set after the great bath complex had collapsed for one of the strong earthquakes that struck Gortys in those times. As the sizes are modest, the kiln is suggested to be a periodic one, used for a short period, but in close connections with some new byzantine constructions and accomodations in the Pretorio area. The paper is also a reconsideration of the evidence on other limekilns in Gortys (in the theater of Pythion, in Byzantine Quarter ecc. and in Crete (the great kiln in Aptera at the end of the classical time.

  6. [Prevention of psychosocial issues and drug addiction in workers employed in building great infrastructures: first outcomes of an experience in the Florence area].

    Science.gov (United States)

    Carpentiero, L; Costa, G; De Luca, G; Piovanelli, S; Venè, D; Righini, S; Marini, M; Baldanzi, S; Selvi, A; Scalas, S; Cassitto, M G; Sartori, S; Lacangellera, D; Bosco, A

    2009-01-01

    The research on stress, mobbing, and substance dependence in workers employed in the building of the great infrastructures is part of the project Euridice-Ten. The 75% of the workers employed took part in the research through an anonymous and structured questionnaire. The Clinica del Lavoro of the University of Milan elaborated the data. They point out a high risk of stress, a low level of control, a marked risk of mobbing, a high chronic fatigue in the most exhausting jobs, sleep disorders, problems in the social life as well as at home, in nourishment and at work. Many workers drink too much alcohol and the 9% of the workers know workers who use cocaine.

  7. Assessment of patient radiation doses in chest X-ray examinations

    International Nuclear Information System (INIS)

    Orsini, S.; Scribano, V.S.; Merluzzi, F.; Tosca, L.

    1987-01-01

    The paper reports the initial results of a radioprotection programme for diagnostic radiology carried out in a major hospital in Milan. The data cover chest X-ray examinations. The dose values were obtained using different techniques, according to the specific diagnostic requirements in each departement. A wide radiation dose range was observed between the different techniques, with a ratio between maximum and minimum dose > 30 for the skin and the spine. The doses were however lower than those capable of inducing non-stochastic effects by about 10000 and were so low that the probability of a stochastics effect is minimal. Nevertheless, because chest X-rays are performed so frequently, it is recommended that radiologists take greater account of patient dose, as far as compatible with diagnostic requirements. Radiology technicians must strictly observe the regulations for radioprotection of the patient

  8. Mucoceles of the oral cavity: a large case series (1994-2008) and a literature review.

    Science.gov (United States)

    Re Cecconi, Dario; Achilli, Antonio; Tarozzi, Marco; Lodi, Giovanni; Demarosi, Federica; Sardella, Andrea; Carrassi, Antonio

    2010-07-01

    Evaluating data of patients affected by oral mucoceles, examined at the Unit of Oral Medicine and Pathology of the University of Milan between January 1994 and December 2008. Concise review on oral mucoceles and analysis of the clinical files of patients who underwent excisional biopsy (patient age, medical history, diagnosis, date and site of the biopsy, histopathological diagnosis and recurrences if any). During the period June 1994-December 2008, 158 mucoceles were observed (93 males and 65 females), with the most frequent site being the lower lip (53%) (p=0.001 by Fisher's test). The mean age of the patients was 31.9 years, with a peak of occurrence in the first four decades of life (75%). Mucoceles are lesions commonly seen in an oral medicine service, mainly affecting young people and lower lips.

  9. Effectiveness, durability, and safety of darunavir/ritonavir in HIV-1-infected patients in routine clinical practice in Italy: a postauthorization noninterventional study

    Directory of Open Access Journals (Sweden)

    Antinori A

    2016-05-01

    Full Text Available Andrea Antinori,1 Paola Meraviglia,2 Antonella d’Arminio Monforte,3,4 Antonella Castagna,5,6 Cristina Mussini,7 Teresa Bini,4 Nicola Gianotti,5 Stefano Rusconi,8 Elisa Colella,8 Giuseppe Airoldi,9 Daniela Mancusi,10 Roberta Termini10 1Clinical Department, National Institute for Infectious Diseases “L. Spallanzani”, Rome, 2Department of Infectious Disease, “L. Sacco” University Hospital, 3Department of Health Sciences – University of Milan, 4Clinic of Infectious Diseases, “San Paolo” Hospital, 5Infectious Diseases, San Raffaele Scientific Institute, 6Università Vita-Salute San Raffaele, Milan, 7Institute of Infectious Diseases, University of Modena and Reggio Emilia, Modena, 8Infectious Diseases Unit, DIBIC Luigi Sacco, University of Milan, 9Studio Associato Airoldi, Cicogna, Ghirri, 10Janssen-Cilag SpA, Medical Affairs, Cologno Monzese, Milan, Italy Abstract: Current antiretroviral (ARV therapy for the treatment of human immunodeficiency virus (HIV-1-infected patients provides long-term control of viral load (VL. Darunavir (DRV is a nonpeptidomimetic protease inhibitor approved for use with a ritonavir booster (DRV/r. This study evaluated the effectiveness of DRV/r in combination with other ARV agents in routine clinical practice in Italy. In this descriptive observational study, data on utilization of DRV/r, under the conditions described in the marketing authorization, were collected from June 2009 to December 2012. Effectiveness (VL <50 copies/mL, tolerability, and durability in four patient groups (two DRV/r-experienced, one ARV-experienced DRV/r-naïve, and one ARV-naïve were analyzed. Secondary objectives included immunological response, safety, and persistence/discontinuation rates. In total, 875 of 883 enrolled patients were included in the analysis: of these, 662 (75.7% completed the follow-up until the end of 2012 and 213 (24.3% withdrew from the study earlier. Initial DRV dose was 600 mg twice daily (67.1% or 800

  10. Microbiological Analysis of Surfaces of Leonardo Da Vinci's Atlantic Codex: Biodeterioration Risk.

    Science.gov (United States)

    Tarsitani, Gianfranco; Moroni, Catia; Cappitelli, Francesca; Pasquariello, Giovanna; Maggi, Oriana

    2014-01-01

    Following the discovery of discoloration on some pages of the Atlantic Codex (AC) of Leonardo da Vinci kept in the Biblioteca Ambrosiana in Milan, some investigations have been carried out to verify the presence of microorganisms, such as bacteria and fungi. To verify the presence of microorganisms a noninvasive method of sampling has been used that was efficient and allowed us to highlight the microbial facies of the material that was examined using conventional microbiological techniques. The microclimatic conditions in the storage room as well as the water content of the volume were also assessed. The combined observations allowed the conclusion that the discoloration of suspected biological origin on some pages of AC is not related to the presence or current attack of microbial agents.

  11. Giovanni Vendramin i iluminacije u inkunabulama samostana Sv. Frane u Šibeniku

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    Bojan Goja

    2015-12-01

    Full Text Available The monastery of the Conventual Franciscans at Šibenik houses a valuable collection of incunables among which the illuminated examples deserve particular attention. The incunable of John Duns Scotus’ Scriptum in quattuor libros Sententiarum Petri Lombardi (Johannes de Colonia et Johannes Manthen, Venice, 1477 is decorated with high-quality figural and phytomorphic illuminations displaying marked similarities with the works of Giovanni Vendramin, a Renaissance miniaturist from Padua. The edition of Caesar’s Commentariorvm de bello Gallico (Milan, Antonius Zarotus, 1477 features decorative frames with white vine stalks (bianchi girari. This type of the decorative frame was frequently used by Giovanni Vendramin and the examples from Šibenik are closely related to some of his works, especially those made for the Bishop of Padua Jacopo Zeno.

  12. Cosmic visits

    CERN Multimedia

    Stefania Pandolfi

    2015-01-01

    On Saturday, 19 September, ESA astronaut Luca Parmitano and Amalia Ercoli Finzi, Principal Investigator of the SD2 experiment on board the ESA Rosetta spacecraft, visited the AMS Control Centre and other CERN installations.   From left to right: Sergio Bertolucci (CERN Director of Research and Computing), Amalia Ercoli Finzi (Emeritus Professor in the Aerospace department of the Polytechnic University of Milan and Principal Investigator of the SD2 experiment on board the ESA Rosetta spacecraft), Maurice Bourquin (AMS-02 Senior Scientist and Honorary Professor in the Nuclear and Corpuscular Physics department of the University of Geneva) and Luca Parmitano (Major in the Italian Air Force and European Space Agency astronaut) in the AMS Payload and Operation Control Centre. They were welcomed in the early morning by Sergio Bertolucci and then headed to the Prévessin site to visit the CERN Control Centre and the Payload and Operation Control Centre (POCC) of the Alpha Magnetic Sp...

  13. From universe to multiverses--and back again.

    Science.gov (United States)

    Tjersland, O A

    1990-12-01

    A number of concepts and ideas from constructivist and second-order cybernetic family therapy literature are presented and their implications for therapy are examined. I was inspired by and, in this article, refer to videotapes of consultations and therapy sessions shown at an international conference on constructivism and family therapy in Sulitjelma, Norway, June 1988, and to written material from the Tromsø group (Tom Andersen and Anna M. Flåm), the Milan team (Luigi Boscolo and Gianfranco Cecchin), and the Galveston team (Harlene Anderson and Harold Goolishian). The article also represents an attempt to use constructivist concepts and ideas in a reflection on the author's own professional development as a psychologist and family therapist.

  14. Public opinion about nuclear energy - year 2003 poll

    International Nuclear Information System (INIS)

    Istenic, R.; Jencic, I.

    2003-01-01

    Nuclear Training Centre Milan Copic at Jozef Stefan Institute in Ljubljana is performing extensive public information activities, focused mainly on elementary and high schools in Slovenia. There are over 7000 visitors yearly. Every year in the spring we ask several hundred of visitors the same set of questions about their knowledge and opinion about nuclear energy. They are polled before they listen to the lecture or visit the exhibition. In that way we are trying to obtain their opinion based on the knowledge they obtain in everyday life. In the paper the results of this year's poll are presented and compared with the previous years. No significant changes in public opinion were observed this year. Favourable attitude towards NPP Krsko, which could be observed in the last years, is maintained. On the other hand, misconceptions about radioactive waste repositories and danger of radioactive waste remain very high. (author)

  15. Essere danzatore e intellettuale nell'Ottocento: danza e scrittura di sé

    Directory of Open Access Journals (Sweden)

    Rita Maria Fabris

    2015-03-01

    Full Text Available Dance researches are not yet familiar with comparative studies, which consist in describing the authority of a “classic” through a repertoire of incidence forms and of reception manners. Our aim, following this perspective, is to critically analyze the canon of the danse d'école and its authority on the pedagogical and performing experiences of Carlo Blasis (1795-1878 in Milan and of August Bournonville (1805-1879 in Copenhagen. By this, we will attempt to identify their processes of appropriation and cultural reworking concerning this ideology on dancing bodies. Our starting point is the analysis of the way the intellectual dancer creates his identity through relationships personal, social, national and international. During the first half of the nineteenth century these relationships are reflected in self-writing and dance-writing, in seek of its own place and praise within the intellectual culture.

  16. Cardinals and the War of Ferrara

    Directory of Open Access Journals (Sweden)

    Stella Fletcher

    2017-12-01

    Full Text Available The bestowal of a red hat can turn even the most humbly born cleric into an ecclesiastical prince, but whereas few cardinals of the modern era have been born princely, most of those created in the Renaissance period could claim to be of noble lineage and a few, from the second half of the fifteenth century onwards, were the sons of ruling princes. Those who were born to fight were obliged to become those who prayed, but where did their allegiances lie when the states of Italy were at war with a belligerent pope such as Sixtus IV? The War of Ferrara (1482–4 presents an opportunity to survey the responses of cardinals from the ruling dynasties of Mantua, Milan, Montferrat, and Naples, together with their counterparts from the republics of Genoa, Siena, and Venice.

  17. Microbiological Analysis of Surfaces of Leonardo Da Vinci’s Atlantic Codex: Biodeterioration Risk

    Directory of Open Access Journals (Sweden)

    Gianfranco Tarsitani

    2014-01-01

    Full Text Available Following the discovery of discoloration on some pages of the Atlantic Codex (AC of Leonardo da Vinci kept in the Biblioteca Ambrosiana in Milan, some investigations have been carried out to verify the presence of microorganisms, such as bacteria and fungi. To verify the presence of microorganisms a noninvasive method of sampling has been used that was efficient and allowed us to highlight the microbial facies of the material that was examined using conventional microbiological techniques. The microclimatic conditions in the storage room as well as the water content of the volume were also assessed. The combined observations allowed the conclusion that the discoloration of suspected biological origin on some pages of AC is not related to the presence or current attack of microbial agents.

  18. Contemporary Strategies in the Management of Hepatocellular Carcinoma

    Directory of Open Access Journals (Sweden)

    Shirin Elizabeth Khorsandi

    2012-01-01

    Full Text Available Liver transplantation is the treatment of choice for selected patients with hepatocellular carcinoma (HCC on a background of chronic liver disease. Liver resection or locoregional ablative therapies may be indicated for patients with preserved synthetic function without significant portal hypertension. Milan criteria were introduced to select suitable patients for liver transplant with low risk of tumor recurrence and 5-year survival in excess of 70%. Currently the incidence of HCC is climbing rapidly and in a current climate of organ shortage has led to the re-evaluation of locoregional therapies and resectional surgery to manage the case load. The introduction of biological therapies has had a new dimension to care, adding to the complexities of multidisciplinary team working in the management of HCC. The aim of this paper is to give a brief overview of present day management strategies and decision making.

  19. Molecular typing of Burkholderia cepacia complex isolated from patients attending an Italian Cystic Fibrosis Centre.

    Science.gov (United States)

    Teri, Antonio; Sottotetti, Samantha; Biffi, Arianna; Girelli, Daniela; D'Accico, Monica; Arghittu, Milena; Colombo, Carla; Corti, Fabiola; Pizzamiglio, Giovanna; Cariani, Lisa

    2018-03-02

    Bacteria from the Burkholderia cepacia complex (Bcc) are capable of causing severe infections in patients with cystic fibrosis (CF). Bcc infection is often extremely difficult to treat due to its intrinsic resistance to multiple antibiotics. In addition, it seems to speed up the decline of lung function and is considered a contraindication for lung transplantation in CF. This study investigates the species of the Bcc strains recovered from chronically infected CF subjects by means of: isolation, identification methods and complete recA nucleotide sequences of 151 samples. Molecular typing showed that B. cenocepacia III is the dominant strain found in the group of subjects being treated at the Milan CF Centre (Italy) and that the infection is chronically maintained by the same species. Defining species by means of molecular analysis yields important information for the clinician in order to establish the most appropriate therapy and implement correct measures for prevention of transmission among CF subjects.

  20. Clustering and Support Vector Regression for Water Demand Forecasting and Anomaly Detection

    Directory of Open Access Journals (Sweden)

    Antonio Candelieri

    2017-03-01

    Full Text Available This paper presents a completely data-driven and machine-learning-based approach, in two stages, to first characterize and then forecast hourly water demand in the short term with applications of two different data sources: urban water demand (SCADA data and individual customer water consumption (AMR data. In the first case, reliable forecasting can be used to optimize operations, particularly the pumping schedule, in order to reduce energy-related costs, while in the second case, the comparison between forecast and actual values may support the online detection of anomalies, such as smart meter faults, fraud or possible cyber-physical attacks. Results are presented for a real case: the water distribution network in Milan.

  1. Public opinion about nuclear energy - year 2004 poll

    International Nuclear Information System (INIS)

    Istenic, R.; Jencic, I.

    2004-01-01

    Public information is one of the permanent activities of the Nuclear Training Centre Milan Copic at Jozef Stefan Institute in Ljubljana. It is focused on youngsters from elementary and high schools in Slovenia that visit the Centre as organized groups. Every year in the spring since 1993 some 800 youngsters are polled with basically the same set of questions inquiring about their knowledge and opinions on nuclear energy. Polling is performed at the beginning of the visit to obtain results based on information from everyday life. In the paper the results of this year's poll are presented and compared with the previous years. The attitude towards NPP Krsko is still favourable but the support has unexpectedly dropped from 83% to 73%. Misconceptions about dangers of nuclear energy and radioactive waste still remain high. (author)

  2. Application of Genetic Algorithms for Driverless Subway Train Energy Optimization

    Directory of Open Access Journals (Sweden)

    Morris Brenna

    2016-01-01

    Full Text Available After an introduction on the basic aspects of electric railway transports, focusing mainly on driverless subways and their related automation systems (ATC, ATP, and ATO, a technique for energy optimization of the train movement through their control using genetic algorithms will be presented. Genetic algorithms are a heuristic search and iterative stochastic method used in computing to find exact or approximate solutions to optimization problems. This optimization process has been calculated and tested on a real subway line in Milan through the implementation of a dedicated Matlab code. The so-defined algorithm provides the optimization of the trains movement through a coast control table created by the use of a genetic algorithm that minimizes the energy consumption and the train scheduled time. The obtained results suggest that the method is promising in minimizing the energy consumption of the electric trains.

  3. Roberto Ruffilli: 25 Years after his Murder. Forlì 26th April 2013

    Directory of Open Access Journals (Sweden)

    Roberto Balzani

    2013-07-01

    Full Text Available In this article Roberto Balzani, the mayor of Forlì, remembers Roberto Ruffilli, 25 years after his murder. The remembrance reconstructs the steps of his academic career and of his political commitment. Ruffilli graduated at the Catholic University of Milan; his researches in contemporary history placed him in an original position if compared with the Italian studies of the time. The constant attention towards the history of administration and the transformations of the state is the basis on which Ruffilli built his proposals concerning the reform of the insitutional and political system. Balzani concludes the article by affirming that the problems of today aren't any different, that is why Ruffilli's proposals still demonstrate their modernity.

  4. ‘Keeping head above water’: A case study in religious leadership in a polluted context

    Directory of Open Access Journals (Sweden)

    Ian A. Nell

    2014-10-01

    Toilets in the modern water closets rise up from the floor like water lilies. The architect does all he can to make the body forget how paltry it is and to make man ignore what happens to his intestinal wastes after the water from the tank flushes them down the drain … Spontaneously, without any theological training, I, as a child, grasped the incompatibility of God and shit and thus came to question the basic thesis of Christian anthropology, namely that man was created in God’s image. Either/or: either man was created in God’s image – and has intestines! – or God lacks intestines and man is not like him. (Milan Kundera, The unbearable lightness of being 1984:132 Water is life, sanitation is dignity. (City of Cape Town, n.d., ‘Water and sanitation services standard’, Preliminary draft 2, March 2008

  5. Ottimizzazione delle opzioni d’uso del suolo agricolo per soddisfare la domanda alimentare: evidenze derivanti dall’applicazione della programmazione lineare ad un’area metropolitana

    Directory of Open Access Journals (Sweden)

    Federica Monaco

    2016-08-01

    Full Text Available Assessing the sustainability of urban agro-food systems is strictly linked with food provision capacities. Especially in metropolitan regions, where agriculture is continuosly under pressure, deepening economic and policy implications of structural changes is particularly important. In this perspective, the paper proposes the use of an optimization model to indicate how reconciling agricultural activities and compliance with food demand at regional level. The approach relies on a scenario analysis carried out through a linear programming model. With regard to the Milan metropolitana area, five scenarios are performed, related to either different productive capacities or dietary habits, and the optimal allocation of agricultural resources in response of such modifications is returned.

  6. Euclid vindicated from every blemish

    CERN Document Server

    2014-01-01

    This first complete English language edition of Euclides vindicatus presents a corrected and revised edition of the classical English translation of Saccheri's text by G.B. Halsted. It is complemented with a historical introduction on the geometrical environment of the time and a detailed commentary that helps to understand the aims and subtleties of the work. Euclides vindicatus, written by the Jesuit mathematician Gerolamo Saccheri, was published in Milan in 1733. In it, Saccheri attempted to reform elementary geometry in two important directions: a demonstration of the famous Parallel Postulate, and the theory of proportions. Both topics were of pivotal importance in the mathematics of the time. In particular, the Parallel Postulate had escaped demonstration since the first attempts at it in the Classical Age, and several books on the topic were published in the Early Modern Age. At the same time, the theory of proportion was the most important mathematical tool of the Galilean School in its pursuit of the...

  7. Experimental study on energy performance of clean air heat pump

    DEFF Research Database (Denmark)

    Fang, Lei; Nie, Jinzhe; Olesen, Bjarne W.

    2014-01-01

    to investigate its energy performance. Energy consumption of the prototype of CAHP was measured in laboratory at different climate conditions including mild-cold, mildhot and extremely hot and humid climates. The energy saving potential of the clean air heat pump compared to a conventional ventilation and air......-conditioning system was calculated. The experimental results showed that the clean air heat pump saved substantial amount of energy compared to the conventional system. For example, the CAHP can save up to 59% of electricity in Copenhagen, up to 40% of electricity in Milan and up to 30% of electricity in Colombo......An innovative clean air heat pump (CAHP) was designed and developed based on the air purification capacity of regenerative silica gel rotor. The clean air heat pump integrated air purification, dehumidification and cooling in one unit. A prototype of the clean air heat pump was developed...

  8. Re-allocating Public Space

    DEFF Research Database (Denmark)

    Figueroa, Maria J.

    not only by state and private actors but includes a strong interplay of civil society organizations with great variations and different degrees of success and failure. The study focused on elements of social innovativeness created in the interplay of actors and on the tensions and issues arising...... which the actors' influence and the narratives produced over time became apparent. The cases traced four European cities Copenhagen, Frankfurt, Milan and Bruno. The most successful case-Copenhagen- demonstrated a long-term build-up of social innovative practices which at their core recreated social......This paper is based on results from a three-year EU project ITSSOIN.EU that investigated impacts of Third Sector as Social innovation in a variety of societal fields. The findings discussed are for the field of environmental sustainability in Cities. The project's empirical work related social...

  9. New solutions in the use of energy. Characteristics for a Mediterranean building; Nouvelles solutions dans l'utilisation de l'energie. Caracteristiques pour un batiment mediterraneen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This document is edited by the regional energy agency of Provence-Alpes-Cote d'Azur region (ARENE) with the participation of the ICAEN (Institut Catala d'Energia) (Barcelona, Spain) and Punto Energia (Milan, Italy) and with the help of the general direction of energy of the European Commission (DG 17, sub-program 'Energy'). It presents the rules for the elaboration of a 'building program' devoted to foremen and which aims at integrating the energy and environmental requirements of a building prior to its construction: 1 - planning (goal, preliminary and feasibility studies); 2 - elaboration of the energy program (environmental context of the project, demand formulation: environmental impact, comfort, electricity and water uses, maintenance, costs..); 3 - characteristics of a Mediterranean building (regional aspect, envelope and passive heating/cooling techniques, active techniques), 4 - energy feasibility study; 5 - evaluation means. (J.S.)

  10. Understanding territorial distribution of Properties of Managers and Shareholders: a Data-driven Approach

    Directory of Open Access Journals (Sweden)

    Stefano Pozzati

    2016-12-01

    Full Text Available The analysis and better understanding of the distribution of wealth of individuals in cities can be a precious tool, especially in support of the estimation of real estate values. These analyses can also be used to facilitate decision making in various sectors, such as public administration or the real estate market. In this paper, by making use of publicly available data and of data owned by Cerved, (a credit scoring company in Italy, we can observe the territorial distribution of the properties of managers and shareholders – categories of people usually linked to high economic well-being – and, based on that, we identify the areas of the cities where the value of real estate properties is presumably higher. More specifically, we introduce the Manager and Shareholder Concentration (MSHC score and validate its accuracy and effectiveness in three Italian cities (Turin, Rome and Milan.

  11. An ecological time-series study of heat-related mortality in three European cities

    Directory of Open Access Journals (Sweden)

    Russo Antonio

    2008-01-01

    Full Text Available Abstract Background Europe has experienced warmer summers in the past two decades and there is a need to describe the determinants of heat-related mortality to better inform public health activities during hot weather. We investigated the effect of high temperatures on daily mortality in three cities in Europe (Budapest, London, and Milan, using a standard approach. Methods An ecological time-series study of daily mortality was conducted in three cities using Poisson generalized linear models allowing for over-dispersion. Secular trends in mortality and seasonal confounding factors were controlled for using cubic smoothing splines of time. Heat exposure was modelled using average values of the temperature measure on the same day as death (lag 0 and the day before (lag 1. The heat effect was quantified assuming a linear increase in risk above a cut-point for each city. Socio-economic status indicators and census data were linked with mortality data for stratified analyses. Results The risk of heat-related death increased with age, and females had a greater risk than males in age groups ≥65 years in London and Milan. The relative risks of mortality (per °C above the heat cut-point by gender and age were: (i Male 1.10 (95%CI: 1.07–1.12 and Female 1.07 (1.05–1.10 for 75–84 years, (ii M 1.10 (1.06–1.14 and F 1.08 (1.06–1.11 for ≥85 years in Budapest (≥24°C; (i M 1.03 (1.01–1.04 and F 1.07 (1.05–1.09, (ii M 1.05 (1.03–1.07 and F 1.08 (1.07–1.10 in London (≥20°C; and (i M 1.08 (1.03–1.14 and F 1.20 (1.15–1.26, (ii M 1.18 (1.11–1.26 and F 1.19 (1.15–1.24 in Milan (≥26°C. Mortality from external causes increases at higher temperatures as well as that from respiratory and cardiovascular disease. There was no clear evidence of effect modification by socio-economic status in either Budapest or London, but there was a seemingly higher risk for affluent non-elderly adults in Milan. Conclusion We found broadly consistent

  12. Typological surveys on the historic city. Actuality of Townhouse

    Directory of Open Access Journals (Sweden)

    Michele Caja

    2016-11-01

    Full Text Available After the rediscovery of the historical city by the Italian urban analysis of the fifties and sixties and the following European urban projects of critical reconstruction, it arises a new awareness of the historical city as an artifact built over time and the possibility of its continuity. This recovered temporal condition of consolidated contexts defines the margin within which it is defined the architectural design of urban living, here exemplified through some didactic experiments carried out in two cities (Berlin and Milan. Among the ways of interventions, almost in a surgical manner, emerges on often-unresolved urban sites the thematic confrontation with the urban block and the townhouse, intended as the minimum element of the architecture of the city.

  13. Two new “CERNland Expert” laureates

    CERN Multimedia

    Valentina Rigamonti

    2013-01-01

    Two classes (46 ten-year-old pupils) from the Primary School of Binago (Como, Italy) participated in the project of the master's thesis by Valentina Rigamonti, a student from the University of Milan. The project was about CERNland, CERN’s website for kids. “CERNland Expert” diplomas and DVDs of the website were the must-have prizes of this original competition. Valentina tells us more about her work.   Winners of the "CERNland drawing competition": Zoe Uboldi (left) and Aminta Invitto. "My thesis project, carried out in collaboration with CERN’s Communication group, was designed to study the impact of communicating science to children using CERNland educational games. Over the course of three meetings the enthusiastic pupils had the opportunity to play with CERNland and participate in various activities to learn first-hand what a scientist is and how science works. At the first meeting, kids drew a scientist, alone ...

  14. Real-time monitoring of railway infrastructures using fibre Bragg grating sensors

    Science.gov (United States)

    Roveri, N.; Carcaterra, A.; Sestieri, A.

    2015-08-01

    In this work we present the results of a field trial with a FBG sensor array system for the real time monitoring of railway traffic and for the structural health monitoring of both the railway track and train wheels. The test campaign is performed on the 2nd line of Milan metropolitan underground, employing more than 50 FBG sensors along 1.5 km of the rail track, where the trains are tested during daily passenger rail transport, with a roughly maximum speeds of 90 km/h. The measurements were continuatively performed for over 6 months, with a sampling frequency of about 400 Hz. The large amount of data/sensors allows a rather accurate statistical treatment of the measurement data and permits, with dedicated algorithms, the estimation of rail and wheel wear, key traffic parameters such as the number of axles, the train speed and load, and, in the next future, the detection of localized imperfections.

  15. Wastewater-based epidemiology to assess pan-European pesticide exposure

    DEFF Research Database (Denmark)

    Rousis, Nikolaos I.; Gracia-Lor, Emma; Zuccato, Ettore

    2017-01-01

    -tandem mass spectrometry. The mass loads (mg/day/1000 inhabitants) were highest for organophosphates and lowest for triazines. Different patterns were observed among the cities and for the various classes of pesticides. Population weighted loads of specific biomarkers indicated higher exposure in Castellon......) is an innovative approach based on the chemical analysis of specific human metabolic excretion products (biomarkers) in wastewater, and provides objective and real-time information on xenobiotics directly or indirectly ingested by a population. This study applied the WBE approach for the first time to evaluate......, Milan, Copenhagen and Bristol for pyrethroids, and in Castellon, Bristol and Zurich for organophosphates. The lowest mass loads (mg/day/1000 inhabitants) were found in Utrecht and Oslo. These results were in agreement with several national statistics related to pesticides exposure such as pesticides...

  16. 5th International Workshop on Complex Networks and their Applications

    CERN Document Server

    Gaito, Sabrina; Quattrociocchi, Walter; Sala, Alessandra

    2017-01-01

    This book highlights cutting-edge research in the field of network science, offering scientists, researchers and graduate students a unique opportunity to catch up on the latest advances in theory and a multitude of applications. It presents the peer-reviewed proceedings of the fifth International Workshop on Complex Networks & their Applications (COMPLEX NETWORKS 2016), which took place in Milan during the last week of November 2016. The carefully selected papers are divided into 11 sections reflecting the diversity and richness of research areas in the field. More specifically, the following topics are covered: Network models; Network measures; Community structure; Network dynamics; Diffusion, epidemics and spreading processes; Resilience and control; Network visualization; Social and political networks; Networks in finance and economics; Biological and ecological networks; and Network analysis.

  17. Case study: Teaching European Active Citizenship (TEACh)-course, EU

    DEFF Research Database (Denmark)

    Milana, Marcella; Bernt Sorensen, Tore

    2007-01-01

    education. Among these projects, the Teaching European Active Citizenship (TEACh)-course was considered worth of a closer examination due to several reasons. Firstly, the course constitutes a follow-up of a Socrates research project which was co-financed by the European Commission within the same action...... scheme. The influence of prior research activity that was carried out at European level on the TEACh-course is evident in both the curriculum and the pedagogical approach applied. In this respect the course represents an example of dissemination of research results of EU co-financed projects as well....... The case study presented here is based on results from desk research and field work carried out over 9 months (autumn 2006-summer 2007). Data was collected by a combination of qualitative methods. The main source of information was participant observation at the TEACh course held in Milan (Italy...

  18. STUDY ON FINANCIAL COMMUNICATIONS FROM PUBLIC RETAIL COMPANIES: COMPARATIVE ANALYSIS – MILANO STOCK EXCHANGE AND BUCHAREST STOCK EXCHANGE

    Directory of Open Access Journals (Sweden)

    Veronica R GROSU

    2016-09-01

    Full Text Available The economic and financial crisis that hit the world economy has shown that for retail companies, growth continued to record only for those who held full control over every point of sale. The objective of our work is focused on the analysis of the most important financial indicators that a retail company should focus on and include in communication with external stakeholders. We make the connection with problems of the real economy through a comparative study of Romania and Italy, in which we analyze retail companies listed on the Bucharest Stock Exchange (BSE and a similar number of retail companies listed on the Milan Stock Exchange (MSE. The importance of the topic stems from the fact that it is essential for understanding how consumers relate the various retail companies and how the latter model their structure or behavior depending on the requirements and needs of the former.

  19. La Società Umanitaria e la diffusione del Metodo Montessori (1908-1923

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    Irene Pozzi

    2015-07-01

    Full Text Available The Società Umanitaria ofMilan, between 1918 and 1923, played an essential role in spreading and developing the Montessori Method. Studying in the Historical Archive of Società Umanitaria the numerous documents there collected, the author reconstructed the crucial moments of the extremely significant collaboration between Maria Montessori and Augusto Osimo, General Secretary of the Società Umanitaria.This complex and in-depth investigation was guided by the analysis, in specific, of the training courses for Montessori teachers organised by Società Umanitaria, essentially unexamined before this study, that allowed the researcher to have a deep insight into the action of Società Umanitaria aimed to promote and implement the Montessori Method in Italy and all around the world.

  20. Simulation and interpretation codes for the JET ECE diagnostic. Part 1: physics of the codes' operation

    International Nuclear Information System (INIS)

    Bartlett, D.V.

    1983-06-01

    The codes which have been developed for the analysis of electron cyclotron emission measurements in JET are described. Their principal function is to interpret the spectra measured by the diagnostic so as to give the spatial distribution of the electron temperature in the poloidal cross-section. Various systematic effects in the data are corrected using look-up tables generated by an elaborate simulation code. The part of this code responsible for the accurate calculation of single-pass emission and refraction has been written at CNR-Milan and is described in a separate report. The present report is divided into two parts. This first part describes the methods used for the simulation and interpretation of spectra, the physical/mathematical basis of the codes written at CEA-Fontenay and presents some illustrative results