Sample records for subject unknown mission

  1. Subjective Sleep Experience During Shuttle Missions (United States)

    Whitmire, Alexandra; Slack, Kelley; Locke, James; Patterson, Holly; Faulk, Jeremy; Keeton, Kathryn; Leveton, Lauren


    It is now known that for many astronauts, sleep is reduced in spaceflight. Given that sleep is intimately tied to performance, safety, health, and well being, it is important to characterize factors that hinder sleep in space, so countermeasures can be implemented. Lessons learned from current spaceflight can be used to inform the development of space habitats and mitigation strategies for future exploration missions. The purpose of this study was to implement a survey and one-on-one interviews to capture Shuttle flyers' subjective assessment of the factors that interfered with a "good nights sleep" during their missions. Strategies that crewmembers reported using to improve their sleep quality during spaceflight were also discussed. Highlights from the interview data are presented here.

  2. Investigation of Tinnitus Characteristics in 36 Patients with Subjective Tinnitus with Unknown Etiology

    Directory of Open Access Journals (Sweden)

    Mahdi Bakhshaee


    Full Text Available Background and Aim: Tinnitus represents the perception of sound without an external stimulus. The prevalence of tinnitus ranges from 3% to 30%. In most cases its etiology is unknown. Tinnitus can be classified as pulsatile or nonpulsatile. Nonpulsatile form is the most common form and almost exclusively subjective in nature. There is a range of condition attributed to nonpulsatile high frequency tinnitus (acoustic neuroma, Meniere’s disease, ototoxic agents, and noise exposure, etc. There are many studies about form, site, loudness, and frequency of tinnitus and how it can affect the quality of patient life. Materials and methods: This was a descriptive and analytic study. Thirty-six patients (23 men and 13 women with mean age 53.1 year old with subjective tinnitus evaluated in Pezhvak audiometric clinic in Mashhad.The data consisting of age sex, loudness, frequency form and site of tinnitus. Evaluation of effects of tinnitus on the quality of life and habits was performed with a tinnitus questionnaire (TQ. Results: Tinnitus was unilateral in 64% of cases. The right site was more common. Mean pitch was 7.03 kHz and average loudness was 3.8 dB SPL. SDS was in normal range in all of patients. There was a high frequency sensory neural hearing loss (above the 4 kHz in most of the patients. The greatest score (60.3% of TQ related to intrusiveness aspect. Sleep disorder has the lowest score (39/3%. Global score was 52.4%. Conclusion: Nonpulsatile subjective tinnitus has a broad range of etiology with unknown mechanism in most cases and without any history of underlying disease in a large group of patients. This symptom mostly involves the patients` lifestyle that is intrusiveness aspect in comparison with the other aspects including sleep, hearing and somatic complaints. There is no cure for most patient and more studies are needed in the future.


    Directory of Open Access Journals (Sweden)

    T. Merz


    Full Text Available This paper presents the design of an autonomous unmanned helicopter system for low-altitude remote sensing. The proposed concepts and methods are generic and not limited to a specific helicopter. The development was driven by the need for a dependable, modular, and affordable system with sufficient payload capacity suitable for both research and real-world deployment. The helicopter can be safely operated without a backup pilot in a contained area beyond visual range. This enables data collection in inaccessible or dangerous areas. Thanks to its terrain following and obstacle avoidance capability, the system does not require a priori information about terrain elevation and obstacles. Missions are specified in state diagrams and flight plans. We present performance characteristics of our system and show results of its deployment in real-world scenarios. We have successfully completed several dozen infrastructure inspection missions and crop monitoring missions facilitating plant phenomics studies.

  4. Performance Testing of Lidar Components Subjected to Space Exposure in Space via MISSE 7 Mission (United States)

    Prasad, Narasimha S.


    .The objective of the Materials International Space Station Experiment (MISSE) is to study the performance of novel materials when subjected to the synergistic effects of the harsh space environment for several months. MISSE missions provide an opportunity for developing space qualifiable materials. Several laser and lidar components were sent by NASA Langley Research Center (LaRC) as a part of the MISSE 7 mission. The MISSE 7 module was transported to the international space station (ISS) via STS 129 mission that was launched on Nov 16, 2009. Later, the MISSE 7 module was brought back to the earth via the STS 134 that landed on June 1, 2011. The MISSE 7 module that was subjected to exposure in space environment for more than one and a half year included fiber laser, solid-state laser gain materials, detectors, and semiconductor laser diode. Performance testing of these components is now progressing. In this paper, the current progress on post-flight performance testing of a high-speed photodetector and a balanced receiver is discussed. Preliminary findings show that detector characteristics did not undergo any significant degradation.

  5. Molecular diagnosis of Fragile X syndrome in subjects with intellectual disability of unknown origin: implications of its prevalence in regional Pakistan.

    Directory of Open Access Journals (Sweden)

    Madiha Kanwal

    Full Text Available Fragile-X syndrome (FXS is the most common form of inherited intellectual disability (ID and affects 0.7-3.0% of intellectually compromised population of unknown etiology worldwide. It is mostly caused by repeat expansion mutations in the FMR1 at chromosome Xq27.3. The present study aimed to develop molecular diagnostic tools for a better detection of FXS, to assess implementation of diagnostic protocols in a developing country and to estimate the prevalence of FXS in a cohort of intellectually disabled subjects from Pakistan. From a large pool of individuals with below normal IQ range, 395 subjects with intellectual disability of unknown etiology belonging to different regions of the country were recruited. Conventional-PCR, modified-PCR and Southern blot analysis methods were employed for the detection of CGG repeat polymorphisms in the FMR1 gene. Initial screening with conventional-PCR identified 13 suspected patients. Subsequent investigations through modified PCR and Southern blot analyses confirmed the presence of the FMR1 mutation, suggesting a prevalence of 3.5% and 2.8% (mean 3.3% among the male and female ID patients, respectively. These diagnostic methods were further customized with the in-house conditions to offer robust screening of referral patients/families for diagnostics and genetic counseling. Prescreening and early diagnosis are crucial for designing a prudent strategy for the management of subjects with ID. Outcome of the study recommends health practitioners for implementation of molecular based FXS diagnosis in routine clinical practice to give a better care for patients similar to the ones included in the study.

  6. Functional and subjective assessment of burn contracture release in a mission setting. (United States)

    Sinha, Indranil; Zhu, Dagny; Ojomo, Kristin; Gfrerer, Lisa; Sawh-Martinez, Rajendra; Patel, Anup; Chan, Rodney K; Watkins, James F


    Burns and subsequent contractures are common in developing nations. Contracture release is performed to treat such patients with functional limitations. The aim of this study is to evaluate post-operative functional and psychosocial outcomes following contracture release in a mission setting. During a surgical mission in Mumbai, India, 39 patients burn contractures underwent surgical release. A total of 31 patients (64% female, mean age 27 years) chose to participate in the study. Patients were scored preoperatively and postoperatively using a SF-36 validated survey and AMA impairment guideline assessment. Thirty-one patients completed questionnaires pre-operative and 6-weeks post operatively. Twenty-four patients completed a survey 3-months post operatively (77.4%). Among those enrolled, 67% were women with the majority sustaining contractures (80.6%). SF-36 physical component score increased from a mean score of 49.8 preoperatively to 55.6 by 3 months following contracture release (Pcontracture release, confirming both functional and psychologic improvement following surgery. During the acute post-operative period, this study suggests that contracture release in a mission setting is of benefit to patients. Copyright © 2015 Elsevier Ltd and ISBI. All rights reserved.

  7. Subjectivity

    Directory of Open Access Journals (Sweden)

    Jesús Vega Encabo


    Full Text Available In this paper, I claim that subjectivity is a way of being that is constituted through a set of practices in which the self is subject to the dangers of fictionalizing and plotting her life and self-image. I examine some ways of becoming subject through narratives and through theatrical performance before others. Through these practices, a real and active subjectivity is revealed, capable of self-knowledge and self-transformation. 

  8. A Subjective Assessment of Alternative Mission Architecture Operations Concepts for the Human Exploration of Mars at NASA Using a Three-Dimensional Multi-Criteria Decision Making Model (United States)

    Tavana, Madjid


    The primary driver for developing missions to send humans to other planets is to generate significant scientific return. NASA plans human planetary explorations with an acceptable level of risk consistent with other manned operations. Space exploration risks can not be completely eliminated. Therefore, an acceptable level of cost, technical, safety, schedule, and political risks and benefits must be established for exploratory missions. This study uses a three-dimensional multi-criteria decision making model to identify the risks and benefits associated with three alternative mission architecture operations concepts for the human exploration of Mars identified by the Mission Operations Directorate at Johnson Space Center. The three alternatives considered in this study include split, combo lander, and dual scenarios. The model considers the seven phases of the mission including: 1) Earth Vicinity/Departure; 2) Mars Transfer; 3) Mars Arrival; 4) Planetary Surface; 5) Mars Vicinity/Departure; 6) Earth Transfer; and 7) Earth Arrival. Analytic Hierarchy Process (AHP) and subjective probability estimation are used to captures the experts belief concerning the risks and benefits of the three alternative scenarios through a series of sequential, rational, and analytical processes.

  9. Converting happiness theory into (interior) architectural design missions. Designing for subjective well-being in residential care centers.


    STEVENS, Ruth; Petermans, Ann; Vanrie, Jan


    Subjective well-being (SWB) is an emerging research topic in the field of design sciences, whereby various design researchers focus on the key question ‘how to design for SWB’. Throughout different design disciplines, definitions for SWB are rising and design models and strategies are being developed in an effort to enable designers to increase users’ SWB. However, a clear image of how to design an (interior) architectural environment with the purpose of increasing people’s level of subjectiv...

  10. Fever of unknown origin

    NARCIS (Netherlands)

    Mulders-Manders, C.; Simon, A.; Bleeker-Rovers, C.P.


    More than 50 years after the first definition of fever of unknown origin (FUO), it still remains a diagnostic challenge. Evaluation starts with the identification of potential diagnostic clues (PDCs), which should guide further investigations. In the absence of PDCs a standardised diagnostic

  11. Cancer of unknown primary

    DEFF Research Database (Denmark)

    Dyrvig, Anne-Kirstine; Yderstræde, Knud Bonnet; Gerke, Oke


    Cancer of unknown primary (CUP) ranges within top 10 cancers in both incidence and mortality. As primary identification is crucial to choosing treatment, guidelines on CUP emphasize the diagnostic strategy. Whether guidelines are complied with, or if they are indeed helpful, is however unclear. We...... to procedures and patient survival. The cohort was investigated in terms of validity of diagnosis through cross-referencing with the Cancer Registry (CR), which served as gold standard for cancer diagnoses and patients' cancer histories.The NPR cohort consisted of 542 patients (275 males, 264 females) of whom...... after 4 years.The validity of a CUP diagnosis in NPR was low when using data from CR as reference. More than half the suspected CUP patients had a previous cancer diagnosis with CUP being the most frequent. Patients were diagnosed in compliance with guidelines indicating high external validity, but less...

  12. [Badminton--unknown sport]. (United States)

    Zekan-Petrinović, Lidija


    For a long time, badminton was considered to be only a slow and light game for children, a game that is played outdoors and is structurally undemanding.Today, it is not an unknown and unrecognised sport, especially after it was included into the Olympics Games in 1992. Badminton is one of the oldest sports in the world. It is suitable for all ages (for children and elderly equally), women and men and even handicapped persons. Beginners can start playing badminton matches early because the basics are learned quickly. As a recreational activity, badminton is very popular in Zagreb. In the last 10 years, a number of halls specialized for badminton or offering badminton as one of available sports activities have been opened in Zagreb. At present, there are over 70 professional playgrounds for training of top contestants but also for the citizens who can play recreational badminton.

  13. Designing towards the unknown

    DEFF Research Database (Denmark)

    Wilde, Danielle; Underwood, Jenny


    interdisciplinary teams with time and resource constraints need to deliver concrete outcomes on schedule. The Poetic Kinaesthetic Interface project (PKI) engages with this problematic directly. In PKI we use unfolding processes—informed by participatory, speculative and critical design—in emergent actions...... the research potential to far-ranging possibilities. In this article we unpack the motivations driving the PKI project. We present our mixed-methodology, which entangles textile crafts, design interactions and materiality to shape an embodied enquiry. Our research outcomes are procedural and methodological....... PKI brings together diverse human, non-human, known and unknown actors to discover where the emergent assemblages might lead. Our approach is re-invigorating—as it demands re-envisioning of—the design process....

  14. Physics: unknown radiation

    CERN Document Server

    Grenier, E; Liksonov, V I; Tsinoiev, V G


    This article reports experiments concerning the study of the electrical explosion of a titanium foil in water. During the electrical discharge a strong luminescence appears, the analysis of spectra shows the presence of new chemical elements and this presence is confirmed by the mass-spectrometry measurements performed on the precipitates found after the discharge. This experiment has been repeated about 200 times and the results are consistent an show an average titanium transmutation rate of 4%. Neither gamma nor neutron radiation have been detected but an unknown radiation, sensitive to magnetic fields, has been detected through tracks left on RF-ZMP fluo-graphical films covered with a 10 mu m-thick emulsion layer. The assumption of a radiation made up of magnetic monopoles is supported by the author. (A.C.)


    African Journals Online (AJOL)


    Mar 2, 1990 ... which would be performed by a robot. There is already pressure to make the use of neuronavigation·devices mandatory, with the implication being that if a device is not used the patient may be subject to undue risk. It may be premature at this stage to suggest that a new technology should be a standard of ...

  16. Imaging an unknown object in an unknown medium

    NARCIS (Netherlands)

    Snieder, R; Wapenaar, C.P.A.


    Imaging an unknown object in a medium that is known, such as a medium with constant velocity, is not difficult because one knows exactly where the waves are when they interact with the object. It is much more challenging to image an object in an unknown medium, because in that case one may know the

  17. Provenance of unknown plutonium material. (United States)

    Nicolaou, G


    The determination of the provenance of 'unknown' plutonium material is demonstrated through a simulation study based on an isotopic fingerprinting approach. Plutonium of known provenance was considered as the 'unknown' nuclear material in order to evaluate the potential of the approach and verify its predictive capabilities. Factor analysis was used to compare the Pu isotopic composition of the 'unknown' material with Pu isotopic compositions simulating well known spent fuels from a range of commercial nuclear power stations. The provenance of the 'unknown material' is assigned to the commercial fuel with which exhibits the highest degree of similarity with respect to the Pu composition. The approach appears promising since it accurately predicted the provenance of the one 'unknown' sample considered; nevertheless, the approach is still at the development stage. Important challenging issues related to the simulation uncertainties and its testing on real laboratory samples have to be explored prior to evaluating the potential of the approach.


    Directory of Open Access Journals (Sweden)

    Y. A. Sidorkina


    Full Text Available The likelihood ratio of the pulse signal with unknown time position while detecting and detecting the signal with unknown frequency, are considered. Is shown that an FFT algorithm should be performed while detecting the signal with unknown frequency, the maximum value of all spectral samples should be found and compared to the detection threshold. Upon detection of a pulse signal with unknown time position a fast convolution algorithm should be performed, the maximum value of all the spectral inverse FFT samples should be found and compared to the detection threshold. The effectiveness of this algorithm is determined by the sampling distribution of the maximum values of random variables distributed according to Rayleigh.

  19. Gas mission; Mission gaz

    Energy Technology Data Exchange (ETDEWEB)



    This preliminary report analyses the desirable evolutions of gas transport tariffing and examines some questions relative to the opening of competition on the French gas market. The report is made of two documents: a synthesis of the previous report with some recommendations about the tariffing of gas transport, about the modalities of network access to third parties, and about the dissociation between transport and trade book-keeping activities. The second document is the progress report about the opening of the French gas market. The first part presents the European problem of competition in the gas supply and its consequences on the opening and operation of the French gas market. The second part presents some partial syntheses about each topic of the mission letter of the Ministry of Economics, Finances and Industry: future evolution of network access tariffs, critical analysis of contractual documents for gas transport and delivery, examination of auxiliary services linked with the access to the network (modulation, balancing, conversion), consideration about the processing of network congestions and denied accesses, analysis of the metering dissociation between the integrated activities of gas operators. Some documents are attached in appendixes: the mission letter from July 9, 2001, the detailed analysis of the new temporary tariffs of GdF and CFM, the offer of methane terminals access to third parties, the compatibility of a nodal tariffing with the presence of three transport operators (GdF, CFM and GSO), the contract-type for GdF supply, and the contract-type for GdF connection. (J.S.)

  20. Identification of unknown nuclear material

    Energy Technology Data Exchange (ETDEWEB)

    Nicolaou, G. [University of Thrace, Department of Electrical and Computer Engineering, Laboratory of Nuclear Technology, Kimmerria Campus, 67100 Xanthi (Greece)


    Aim: provenance determination of unknown nuclear material: - demonstrated for spent nuclear fuel; - information sought for unknown: fuel type, reactor type where fuel was irradiated, final burnup; Using an isotopic finger-printing method: - U, Pu or Pu isotopics or fission products; - simulations of fuel evolution during irradiation, using ORIGEN; - multivariate statistical tools. Fuel considered: simulated commercial spent fuel for a range of burnups: - PWR UO{sub 2} 3.1% and 3.5% {sup 235}U, - PWR thermal MOX, - BWR UO{sub 2} 3.2% {sup 235}U, - CANDU-N natural U, - CANDU-S UO{sub 2} 3.2% {sup 235}U, - fast Reactor MOX; simulated commercial spent fuel for a range of burnups: - PWR UO{sub 2} 3.1% and 3.5% {sup 235}U, - PWR thermal MOX, - BWR UO{sub 2} 3.2% {sup 235}U, - CANDU-N natural U, - CANDU-S UO{sub 2} 3.2% {sup 235}U, - fast Reactor MOX; 'unknown' spent fuel: - PWR 1: UO{sub 2} 3.1% {sup 235}U (26 GWd/t), - PWR 2: UO{sub 2} 3.1% {sup 235}U (32 GWd/t). Procedures: U, Pu or Pu isotopic compositions or fission products: - isotopic composition of unknown spent fuel, - simulated for commercial spent fuel from a range of nuclear power reactors {yields} comparison of compositions through factor analysis {yields} unknown has the provenance of the commercial spent fuel with which it exhibits the most similar composition. In conclusion: different reactor-fuel types well resolved; fuel and reactor type accurately predicted; burnup predicted to within 5% of declared; different reactor-fuel types. (authors)

  1. Function analysis of unknown genes

    DEFF Research Database (Denmark)

    Rogowska-Wrzesinska, A.


      This thesis entitled "Function analysis of unknown genes" presents the use of proteome analysis for the characterisation of yeast (Saccharomyces cerevisiae) genes and their products (proteins especially those of unknown function). This study illustrates that proteome analysis can be used...... be obtained using proteome analysis. Chapter 1 and 2 provide the basic theoretical aspects of proteome analysis, its principles, the main techniques involved and their use in the studies of the molecular biology of yeast cells. Chapter 3 presents the methods and tools involved in proteome analysis and used...... to multiple drug resistance in yeast. It analyses the cellular response to the overexpression of the Pdr5p - an ABC transporter protein that is responsible for resistance of yeast cells to several drugs and chemical compounds. It shows that the overexpression of Pdr5p triggers a strong cell stress response...

  2. Inflammation in Heart Failure: known knowns and unknown unknowns. (United States)

    Cocco, Giuseppe; Jerie, Paul; Amiet, Philipp; Pandolfi, Stefano


    The review deals with inflammation in heart failure (HF). Many data show that systemic inflammation is frequent in HF and implicate that inflammation contributes to damage and dysfunction of the cardiovascular system. Areas Covered: Experimental data have been mainly obtained in acute laboratory animal models. It is questionable whether animals' data can be translated into clinical settings with patients with chronic HF who have concomitant pathologies. The idea of a common inflammatory pathway that characterizes all different forms of clinical HF is unrealistic. It seems realistic that inflammation differs in non-cardiac and cardiac diseases. Research therapeutic options address the use of inhibitors of cytokines, of agents antagonizing oxidative stress, of MMP and of PI3K signaling pathways. Expert Opinion: Considering the many unknowns in our knowledge it is not surprising that early trials aimed to antagonize inflammation in HF have been disappointing. We are far away from having solid therapeutic schedules to use immunomodulation in all subtypes of HF. However, modern trials on HF due to virus infections have proven that immunomodulation is therapeutically effective. We should wisely use the known facts and accept that we have many unknowns. By appropriate selection of the subtypes of HF we may be able to find the appropriate therapy against inflammation in HF.

  3. Cassini Mission

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Robert (Jet Propulsion Laboratory)


    The Cassini/Huygens mission is a joint NASA/European Space Agency/Italian Space Agency project which has a spacecraft currently in orbit about Saturn, and has successfully sent an atmospheric probe through the atmosphere of Saturn's largest moon Titan and down to its previously hidden surface. This presentation will describe the overall mission, how it got a rather massive spacecraft to Saturn, and will cover some of the scientific results of the mission to date.

  4. Carcinoma Telangiectaticum of Unknown Primary

    Directory of Open Access Journals (Sweden)

    Demet Çiçek


    Full Text Available Carcinoma telangiectaticum is an unusual type of cutaneous metastasis originating from various malignant tumors and characterized by telangiectases. This disorder appears with the spread of malignant cells to the skin via superficial lymphatics. It presents as small pink to purplish pseudovesicles, purpuric papules, plaques and telangiectases. A 58-year-old female patient with extensive internal organ metastasis, the primary of which could not be determined, was consulted for bluish lesion on her abdomen, while she was receiving cisplatinum and etoposide combination chemotherapy and radiotherapy. Histopathologic examination revealed that the superficial lymphatics in dermis were attacked by tumoral cells. Final diagnosis was established by clinical and histopathological findings as carcinoma telangiectaticum due to metastasis of a malignant tumor of unknown origin. Unfortunately our patient succumbed during her chemotherapy.

  5. Striving for the unknown normal

    DEFF Research Database (Denmark)

    Nielsen, Mikka

    the ADHD diagnosis both answers and produces existential questions on what counts as normal behaviour and emotions. The diagnosis helps the diagnosed to identify, accept and handle problems by offering concrete explanations and solutions to diffuse experienced problems. But the diagnostic process......-analysing situation trying to answer: What is ADHD and what is me and my personal features? When are the drugs having the right effect? And since I have never been normal then how would I know what behavioural ideal I am striving for? Moreover, the public questioning of the diagnosis calls the individual...... to constantly claiming recognition of the diagnosis. I end by discussing the moral implications of this striving for the unknown normal and ask if the pathologization of inattentive and hyperactive behaviour is to be addressed as a problematic moral issue or if we have a moral obligation to help people who...

  6. NEEMO 7 undersea mission (United States)

    Thirsk, Robert; Williams, David; Anvari, Mehran


    The NEEMO 7 mission was the seventh in a series of NASA-coordinated missions utilizing the Aquarius undersea habitat in Florida as a human space mission analog. The primary research focus of this mission was to evaluate telementoring and telerobotic surgery technologies as potential means to deliver medical care to astronauts during spaceflight. The NEEMO 7 crewmembers received minimal pre-mission training to perform selected medical and surgical procedures. These procedures included: (1) use of a portable ultrasound to locate and measure abdominal organs and structures in a crewmember subject; (2) use of a portable ultrasound to insert a small needle and drain into a fluid-filled cystic cavity in a simulated patient; (3) surgical repair of two arteries in a simulated patient; (4) cystoscopy and use of a ureteral basket to remove a renal stone in a simulated patient; and (5) laparoscopic cholecystectomy in a simulated patient. During the actual mission, the crewmembers performed the procedures without or with telementoring and telerobotic assistance from experts located in Hamilton, Ontario. The results of the NEEMO 7 medical experiments demonstrated that telehealth interventions rely heavily on a robust broadband, high data rate telecommunication link; that certain interventional procedures can be performed adequately by minimally trained individuals with telementoring assistance; and that prior clinical experience does not always correlate with better procedural performance. As space missions become longer in duration and take place further from Earth, enhancement of medical care capability and expertise will be required. The kinds of medical technologies demonstrated during the NEEMO 7 mission may play a significant role in enabling the human exploration of space beyond low earth orbit, particularly to destinations such as the Moon and Mars.

  7. [Energy drinks: an unknown risk]. (United States)

    Petit, Aymeric; Levy, Fanny; Lejoyeux, Michel; Reynaud, Michel; Karila, Laurent


    The term "energy drink" designates "any product in the form of a drink or concentrated liquid, which claims to contain a mixture of ingredients having the property to raise the level of energy and vivacity". The main brands, Red Bull, Dark Dog, Rockstar, Burn, and Monster, are present in food stores, sports venues, and bars among other soft drinks and fruit juices. Their introduction into the French market raised many reluctances, because of the presence of taurine, caffeine and glucuronolactone. These components present in high concentrations, could be responsible for adverse effects on health. The association of energy drinks and spirits is widely found among adolescents and adults who justify drinking these mixed drinks by their desire to drink more alcohol while delaying drunkenness. Given the importance of the number of incidents reported among the energy drinks consumers, it seemed appropriate to make a synthesis of available data and to establish causal links between the use of these products and the development of health complications. For a literature review, we selected scientific articles both in English and French published between 2001 and 2011 by consulting the databases Medline, Embase, PsycINFO and Google Scholar. The words used alone or in combination are "energy dinks", "caffeine", "taurine", "toxicity", "dependence". An occasional to a moderate consumption of these drinks seems to present little risk for healthy adults. However, excessive consumption associated with the use of alcohol or drugs in amounts that far exceed the manufacturers recommended amount, could be responsible for negative consequences on health, particularly among subjects with cardiovascular disease.

  8. Unknown Risks: Parental Hesitation about Vaccination. (United States)

    Blaisdell, Laura L; Gutheil, Caitlin; Hootsmans, Norbert A M; Han, Paul K J


    This qualitative study of a select sample of vaccine-hesitant parents (VHPs) explores perceived and constructed personal judgments about the risks and uncertainties associated with vaccines and vaccine-preventable diseases (VPDs) and how these subjective risk judgments influence parents' decisions about childhood vaccination. The study employed semistructured focus group interviews with 42 VHPs to elicit parents' perceptions and thought processes regarding the risks associated with vaccination and nonvaccination, the sources of these perceptions, and their approach to decision making about vaccination for their children. VHPs engage in various reasoning processes and tend to perceive risks of vaccination as greater than the risks of VPDs. At the same time, VHPs engage in other reasoning processes that lead them to perceive ambiguity in information about the harms of vaccination-citing concerns about the missing, conflicting, changing, or otherwise unreliable nature of information. VHPs' refusal of vaccination may reflect their aversion to both the risk and ambiguity they perceive to be associated with vaccination. Mitigating this vaccine hesitancy likely requires reconstructing the risks and ambiguities associated with vaccination-a challenging task that requires providing parents with meaningful evidence-based information on the known risks of vaccination versus VPDs and explicitly acknowledging the risks that remain truly unknown. © The Author(s) 2015.

  9. Controlled unknown quantum operations on hybrid systems (United States)

    He, Yong; Luo, Ming-Xing


    Any unknown unitary operations conditioned on a control system can be deterministically performed if ancillary subspaces are available for the target systems [Zhou X Q, et al. 2011 Nat. Commun. 2 413]. In this paper, we show that previous optical schemes may be extended to general hybrid systems if unknown operations are provided by optical instruments. Moreover, a probabilistic scheme is proposed when the unknown operation may be performed on the subspaces of ancillary high-dimensional systems. Furthermore, the unknown operations conditioned on the multi-control system may be reduced to the case with a control system using additional linear circuit complexity. The new schemes may be more flexible for different systems or hybrid systems. Project supported by the National Natural Science Foundation of China (Grant Nos. 61303039 and 61201253), Chunying Fellowship, and Fundamental Research Funds for the Central Universities, China (Grant No. 2682014CX095).

  10. Fever of unknown origin in rheumatic diseases. (United States)

    Zenone, Thierry


    Noninfectious inflammatory diseases (connective tissue diseases, vasculitis syndromes, granulomatous diseases) emerged as the most frequent cause of fever of unknown origin in western countries. Among these diseases, giant cell arteritis and polymyalgia rheumatica are the most frequent specific diagnosis in the elderly and adult-onset Still's disease the most frequent in younger patients. This article focuses on noninfectious inflammatory diseases as a cause of classic fever of unknown origin (mainly rheumatic diseases, such as vasculitis and connective tissue diseases).

  11. From rankings to mission. (United States)

    Kirch, Darrell G; Prescott, John E


    Since the 1980s, school ranking systems have been a topic of discussion among leaders of higher education. Various ranking systems are based on inadequate data that fail to illustrate the complex nature and special contributions of the institutions they purport to rank, including U.S. medical schools, each of which contributes uniquely to meeting national health care needs. A study by Tancredi and colleagues in this issue of Academic Medicine illustrates the limitations of rankings specific to primary care training programs. This commentary discusses, first, how each school's mission and strengths, as well as the impact it has on the community it serves, are distinct, and, second, how these schools, which are each unique, are poorly represented by overly subjective ranking methodologies. Because academic leaders need data that are more objective to guide institutional development, the Association of American Medical Colleges (AAMC) has been developing tools to provide valid data that are applicable to each medical school. Specifically, the AAMC's Medical School Admissions Requirements and its Missions Management Tool each provide a comprehensive assessment of medical schools that leaders are using to drive institutional capacity building. This commentary affirms the importance of mission while challenging the leaders of medical schools, teaching hospitals, and universities to use reliable data to continually improve the quality of their training programs to improve the health of all.

  12. Fast grasping of unknown objects using principal component analysis (United States)

    Lei, Qujiang; Chen, Guangming; Wisse, Martijn


    Fast grasping of unknown objects has crucial impact on the efficiency of robot manipulation especially subjected to unfamiliar environments. In order to accelerate grasping speed of unknown objects, principal component analysis is utilized to direct the grasping process. In particular, a single-view partial point cloud is constructed and grasp candidates are allocated along the principal axis. Force balance optimization is employed to analyze possible graspable areas. The obtained graspable area with the minimal resultant force is the best zone for the final grasping execution. It is shown that an unknown object can be more quickly grasped provided that the component analysis principle axis is determined using single-view partial point cloud. To cope with the grasp uncertainty, robot motion is assisted to obtain a new viewpoint. Virtual exploration and experimental tests are carried out to verify this fast gasping algorithm. Both simulation and experimental tests demonstrated excellent performances based on the results of grasping a series of unknown objects. To minimize the grasping uncertainty, the merits of the robot hardware with two 3D cameras can be utilized to suffice the partial point cloud. As a result of utilizing the robot hardware, the grasping reliance is highly enhanced. Therefore, this research demonstrates practical significance for increasing grasping speed and thus increasing robot efficiency under unpredictable environments.

  13. Multidimensional procurement auctions with unknown weights

    DEFF Research Database (Denmark)

    Greve, Thomas

    the principal and the agents leads to unclear reaction strategies. I show that an unknown weight on the principal’s valuation of quality leads to the production of to much quality and to high informational rent. A problem that can be reduced using a revelation mechanism. Having an unknown weight on quality...... gives rise to an analysis of a principal that can not fully commit to the outcome induced by the scoring rule. Therefore, my result apply to contract theory and it’s problems with imperfect commitment....

  14. Protocol for counterfactually transporting an unknown qubit

    Directory of Open Access Journals (Sweden)

    Hatim eSalih


    Full Text Available Quantum teleportation circumvents the uncertainty principle using dual channels: a quantum one consisting of previously-shared entanglement, and a classical one, together allowing the disembodied transport of an unknown quantum state over distance. It has recently been shown that a classical bit can be counterfactually communicated between two parties in empty space, Alice and Bob. Here, by using our dual version of the chained quantum Zeno effect to achieve a counterfactual CNOT gate, we propose a protocol for transporting an unknown qubit counterfactually, that is without any physical particles travelling between Alice and Bob—no classical channel and no previously-shared entanglement.

  15. Protocol for counterfactually transporting an unknown qubit (United States)

    Salih, Hatim


    Quantum teleportation circumvents the uncertainty principle using dual channels: a quantum one consisting of previously-shared entanglement, and a classical one, together allowing the disembodied transport of an unknown quantum state over distance. It has recently been shown that a classical bit can be counterfactually communicated between two parties in empty space, “Alice” and “Bob”. Here, by using our “dual” version of the chained quantum Zeno effect to achieve a counterfactual CNOT gate, we propose a protocol for transporting an unknown qubit counterfactually, that is without any physical particles travelling between Alice and Bob—no classical channel and no previously-shared entanglement.

  16. Autonomous Underwater Navigation and Optical Mapping in Unknown Natural Environments

    Directory of Open Access Journals (Sweden)

    Juan David Hernández


    Full Text Available We present an approach for navigating in unknown environments while, simultaneously, gathering information for inspecting underwater structures using an autonomous underwater vehicle (AUV. To accomplish this, we first use our pipeline for mapping and planning collision-free paths online, which endows an AUV with the capability to autonomously acquire optical data in close proximity. With that information, we then propose a reconstruction pipeline to create a photo-realistic textured 3D model of the inspected area. These 3D models are also of particular interest to other fields of study in marine sciences, since they can serve as base maps for environmental monitoring, thus allowing change detection of biological communities and their environment over time. Finally, we evaluate our approach using the Sparus II, a torpedo-shaped AUV, conducting inspection missions in a challenging, real-world and natural scenario.

  17. Autonomous Underwater Navigation and Optical Mapping in Unknown Natural Environments. (United States)

    Hernández, Juan David; Istenič, Klemen; Gracias, Nuno; Palomeras, Narcís; Campos, Ricard; Vidal, Eduard; García, Rafael; Carreras, Marc


    We present an approach for navigating in unknown environments while, simultaneously, gathering information for inspecting underwater structures using an autonomous underwater vehicle (AUV). To accomplish this, we first use our pipeline for mapping and planning collision-free paths online, which endows an AUV with the capability to autonomously acquire optical data in close proximity. With that information, we then propose a reconstruction pipeline to create a photo-realistic textured 3D model of the inspected area. These 3D models are also of particular interest to other fields of study in marine sciences, since they can serve as base maps for environmental monitoring, thus allowing change detection of biological communities and their environment over time. Finally, we evaluate our approach using the Sparus II, a torpedo-shaped AUV, conducting inspection missions in a challenging, real-world and natural scenario.

  18. 39 CFR 946.4 - Disposition of property of unknown owners. (United States)


    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Disposition of property of unknown owners. 946.4 Section 946.4 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PROCEDURE RELATING TO THE... § 946.4 Disposition of property of unknown owners. (a) Where no apparent owner of property subject to...

  19. Method for genetic identification of unknown organisms

    Energy Technology Data Exchange (ETDEWEB)

    Colston, Jr., Billy W.; Fitch, Joseph P.; Hindson, Benjamin J.; Carter, Chance J.; Beer, Neil Reginald


    A method of rapid, genome and proteome based identification of unknown pathogenic or non-pathogenic organisms in a complex sample. The entire sample is analyzed by creating millions of emulsion encapsulated microdroplets, each containing a single pathogenic or non-pathogenic organism sized particle and appropriate reagents for amplification. Following amplification, the amplified product is analyzed.

  20. Ovine wet carcass syndrome of unknown aetiology

    African Journals Online (AJOL)

    plicating cachexia, inflammatory processes, lymphoedema, cardiac failure, glycogen storage or myxoedema in the pathogenesis of the syndrome. In conclusion, despite intensive investigation the aeti- ology of the wet carcase syndrome remains unknown. At present the possibility of a histamine reaction due to insect bites is ...

  1. Christian Petzold’s melodramas : From unknown woman to reciprocal unknownness in Phoenix, Wolfsburg, and Barbara

    NARCIS (Netherlands)

    Staat, W.


    Stanley Cavell’s theory of film melodrama is used for Christian Petzold’s Phoenix, Wolfsburg, and Barbara. Key for Cavell’s understanding of classical Hollywood melodrama is his notion of the ‘unknown woman.’ Remarkably, Petzold’s more contemporary melodramas feature unknown, i.e. unacknowledged,

  2. Melanoma of unknown origin: a case series.

    LENUS (Irish Health Repository)

    Kelly, J


    The natural history of metastatic melanoma involving lymph nodes, in the absence of a known primary site (cutaneous, ocular or mucosal) has, to date, been poorly defined; and the optimal management of this rare subtype of disease is therefore unclear. Melanomas of unknown primary site (MUP) are estimated to comprise between 3.7 and 6% of all melanomas (Anbari et al. in Cancer 79:1861-1821, 1997).

  3. Fever of unknown origin (FUO) revised. (United States)

    Unger, Manuel; Karanikas, Georgios; Kerschbaumer, Andreas; Winkler, Stefan; Aletaha, Daniel


    Fever of unknown origin (FUO) was originally characterised in 1961 by Petersdorf and Beeson as a disease condition of temperature exceeding 38.3 °C on at least three occasions over a period of at least three weeks, with no diagnosis made despite one week of inpatient investigation. However, since underlying diseases are often reported for classical FUO, these presentations may not be considered to be of "unknown origin". Rather, the aetiology of prolonged fever may resolve, or not resolve. The definition of fever with unresolved cause (true FUO) is difficult, as it is a moving target, given the constant advancement of imaging and biomarker analysis. Therefore, the prevalence of fever with unresolved cause (FUO) is unknown.In this review, we report such a case of prolonged fever, which initially has presented as classical FUO, and discuss current literature. Furthermore, we will give an outlook, how a prospective study on FUO will allow to solve outstanding issues like the utility of different diagnostic investigations, and the types and prevalence of various underlying diseases.

  4. Solar sail mission design

    Energy Technology Data Exchange (ETDEWEB)

    Leipold, M.


    The main subject of this work is the design and detailed orbit transfer analysis of space flight missions with solar sails utilizing solar pressure for primary propulsion. Such a sailcraft requires ultra-light weight, gossamer-like deployable structures and materials in order to effectively utilize the transfer of momentum of solar photons. Different design concepts as well as technological elements for solar sails are considered, and an innovative design of a deployable sail structure including new methods for sail folding and unfolding is presented. The main focus of this report is on trajectory analysis, simulation and optimization of planetocentric as well as heliocentric low-thrust orbit transfers with solar sails. In a parametric analysis, geocentric escape spiral trajectories are simulated and corresponding flight times are determined. In interplanetary space, solar sail missions to all planets in our solar system as well as selected minor bodies are included in the analysis. Comparisons to mission concepts utilizing chemical propulsion as well as ion propulsion are included in order to assess whether solar sailing could possibly enhance or even enable this mission. The emphasis in the interplanetary mission analysis is on novel concepts: a unique method to realize a sun-synchronous Mercury orbiter, fast missions to the outer planets and the outer heliosphere applying a ''solar photonic assist'', rendezvous and sample return missions to asteroids and comets, as well as innovative concepts to reach unique vantage points for solar observation (''Solar Polar Orbiter'' and ''Solar Probe''). Finally, a propellant-less sailcraft attitude control concept using an external torque due to solar pressure is analyzed. Examples for sail navigation and control in circular Earth orbit applying a PD-control algorithm are shown, illustrating the maneuverability of a sailcraft. (orig.) [German] Gegenstand dieser

  5. Subject Index

    Indian Academy of Sciences (India)

    ray. Spectrometer (SOXS) Mission ... Luminosity Dependent Study of the High Mass X-ray Binary Pulsar 4U 0114 + 65 with ASCA (U. Mukherjee & B. ... Magnetic Source Regions of Coronal Mass Ejections (Brigitte Schmieder), 139. North–South ...

  6. Fever of unknown origin in elderly patients. (United States)

    Knockaert, D C; Vanneste, L J; Bobbaers, H J


    To describe the spectrum of diseases that may give rise to fever of unknown origin in elderly patients and to delineate the diagnostic approach in these patients. Subgroup analysis of a prospectively collected case series followed more than 2 years. General Internal Medicine Service based at University hospital, Leuven, Belgium. Forty-seven consecutive patients, older than 65 years, meeting the classic criteria of fever of unknown origin. The final diagnosis established and the clinical value of diagnostic procedures. Infections, tumors and multisystem diseases (encompassing rheumatic diseases, connective tissue disorders, vasculitis including temporal arteritis, polymyalgia rheumatica, and sarcoidosis) were found in 12 (25%), six (12%) and 15 patients (31%), respectively. Drug-related fever was the cause in three patients (6%), miscellaneous conditions were found in five patients (10%), and six patients (12%) remained undiagnosed. Microbiologic investigations were diagnostic in eight cases (16%), serologic tests yielded one diagnosis, immunologic investigations had a diagnostic value in four cases, standard X-rays yielded a diagnostic contribution in 10 cases, ultrasonography and computed tomography were diagnostic in 11 cases, Gallium scintigraphy had a diagnostic contribution in 17 cases, and biopsies yielded the final diagnosis in 18 cases. Multisystem diseases emerged as the most frequent cause of fever of unknown origin in the elderly, and temporal arteritis was the most frequent specific diagnosis. Infections, particularly tuberculosis, remain an important group. The percentage of tumors was higher in our elderly patients than in the younger ones but still clearly lower than in other recent series of FUO in adults. The number of undiagnosed cases was significantly lower in elderly patients than in younger individuals (P < or = 0.01). The investigation of elderly patients with FUO should encompass routine temporal artery biopsy and extensive search for

  7. To Know The Way To The Unknown

    DEFF Research Database (Denmark)

    Boysen, Mikkel Snorre Wilms


    , in various ways, expertise plays an important part in creative processes. However, the case studies also indicate that expertise sometimes leads to an entrenched perspective, in the sense that knowledge and experience may work as a path into the well-known rather than into the unknown. In this article......, these issues are explored with reference to different theoretical approaches to creativity and learning, including actor-network theory, the theory of blind variation and selective retention, and Csikszentmihalyi’s system model. Finally, some educational aspects and implications of this are discussed....


    Directory of Open Access Journals (Sweden)

    Fotache Lacramioara


    Full Text Available The paper is an effort to unknown areas identity affirmation, through collaborative development of advertising mix, with an emphasis on virtual platforms as admissible solution for increasing visibility. Based upon comparative effective analysis of categories of communication particularities, it is suggested a positioning strategic solution, via virtual advertising platform as unique, integrated, complex and very attractive tourism product promotion, fitted for the internal and international tourism circuit. The active promotion of the specified territorial identity will launch a brand with an impact among tourists by using marketing techniques and innovating technical means and prioritizing tourism as a principal vector of local and regional development.

  9. Chronic Traumatic Encephalopathy: Known Causes, Unknown Effects. (United States)

    Iacono, Diego; Shively, Sharon B; Edlow, Brian L; Perl, Daniel P


    Chronic traumatic encephalopathy (CTE) is a neuropathologic diagnosis typically made in human brains with a history of repetitive traumatic brain injury (rTBI). It remains unknown whether CTE occurs exclusively after rTBI, or whether a single TBI (sTBI) can cause CTE. Similarly, it is unclear whether impact (eg, motor vehicle accidents) and non-impact (eg, blasts) types of energy transfer trigger divergent or common pathologies. While it is established that a history of rTBI increases the risk of multiple neurodegenerative diseases (eg, dementia, parkinsonism, and CTE), the possible pathophysiologic and molecular mechanisms underlying these risks have yet to be elucidated. Published by Elsevier Inc.

  10. Missional theological curricula and institutions

    Directory of Open Access Journals (Sweden)

    Kruger P. du Preez


    Full Text Available The article argues in favour of an all-embracing missional framework for curriculum development for theological institutions. When the curriculum of a subject such as ecclesiologyhas a missional hermeneutic, it will naturally lead to missional congregations. The authors use issues raised by the Network for African Congregational Theology (NetACT institutions and the decisions of the Third Lausanne Congress in Cape Town (2010 as reference points in this article. They argue for a broad understanding of the concept �missional� and are of the opinion that curricula that are integrative, normative, contextual and missional will lead to spiritual maturity and will result in a positive impact on church and society as a whole. The missio Deias the work of the Trinitarian God is seen as being God�s initiative. The incarnational modelof Jesus Christ forms the basis for a theology and missiology where humility, vulnerability and servanthood play a pivotal role in curricula. An appeal is made for holistic missions with a strong emphasis on social engagement and the inclusion of community development. The Holy Spirit is seen as the empowering presence of the missio Dei, and the role of pneumatologyin missional curriculum development is underscored. Theological institutes should become�proclamation� institutions. Curricula should be ecumenical by nature and should include reaching the unreached and unengaged people groups. Theological education by extension is presented as an alternative way of decent ralised theological education.Intradisciplinary and/or interdisciplinary implications: The article calls for theology to be done with a missional hermeneutic, both intradisciplinarily and interdisciplinarily. The article involves theology and education and calls for all disciplines dealing with community development to collaborate.

  11. The Unknown Component Problem Theory and Applications

    CERN Document Server

    Villa, Tiziano; Brayton, Robert K; Mishchenko, Alan; Petrenko, Alexandre; Sangiovanni-Vincentelli, Alberto


    The Problem of the Unknown Component: Theory and Applications addresses the issue of designing a component that, combined with a known part of a system, conforms to an overall specification. The authors tackle this problem by solving abstract equations over a language. The most general solutions are studied when both synchronous and parallel composition operators are used. The abstract equations are specialized to languages associated with important classes of automata used for modeling systems. The book is a blend of theory and practice, which includes a description of a software package with applications to sequential synthesis of finite state machines. Specific topologies interconnecting the components, exact and heuristic techniques, and optimization scenarios are studied. Finally the scope is enlarged to domains like testing, supervisory control, game theory and synthesis for special omega languages. The authors present original results of the authors along with an overview of existing ones.

  12. Adresse inconnue / Address unknown / Suchwiin Bulmyeong

    Directory of Open Access Journals (Sweden)

    Serge Gruzinski


    Full Text Available Tous les films asiatiques parlent de métissage, même ceux qui se présentent comme de vastes fresques historiques perdues dans le temps. Les emprunts aux traditions hollywoodiennes et européennes n'ont cessé d'enrichir une cinématographie aussi ancienne que celle du monde occidental. Dans Adresse inconnue (Address unknown le cinéaste coréen Kim Ki-duk explore l'expérience du métissage et le corps du métis à la frontière entre Corée du Nord et Corée du sud. Fils d'un GI américain et noir et d...

  13. Carcinomatous Meningitis from Unknown Primary Carcinoma

    Directory of Open Access Journals (Sweden)

    L. Favier


    Full Text Available Carcinomatous meningitis (CM occurs in 3 to 8% of cancer patients. Patients present with a focal symptom, and multifocal signs are often found following neurological examination. The gold standard for diagnosis remains the demonstration of carcinomatous cells in the cerebrospinal fluid on cytopathological examination. Despite the poor prognosis, palliative treatment could improve quality of life and, in some cases, overall survival. We report on a patient who presented with vertigo, tinnitus and left-sided hearing loss followed by progressive diffuse facial nerve paralysis. Lumbar cerebrospinal fluid confirmed the diagnosis of CM. However, no primary tumor was discovered, even after multiple invasive investigations. This is the first reported case in the English-language medical literature of CM resulting from a carcinoma of unknown primary origin.

  14. Information gain when measuring an unknown qubit (United States)

    Björk, Gunnar


    In quantum information the fundamental information-containing system is the qubit. A measurement of a single qubit can at most yield one classical bit. However, a dichotomous measurement of an unknown qubit will yield much less information about the qubit state. We use Bayesian inference to compute how much information one progressively gets by making sucessive, individual measurements on an ensemble of identically prepared qubits. Perhaps surprisingly, even if the measurements are arranged so that each measurement yields one classical bit, that is, the two possible measurement outcomes are a priori equiprobable, it takes almost a handful of measurements before one has gained one bit of information about the gradually concentrated qubit probability density. We also show that by following a strategy that reaps the maximum information per measurement, we are led to a mutually unbiased basis as our measurement bases. This is a pleasing, although not entirely surprising, result.

  15. Education Through Exploration: Evaluating the Unknown (United States)

    Anbar, A. D.


    Mastery of the peculiar and powerful practices of science is increasingly important for the average citizen. With the rise of the Internet, most of human knowledge is at our fingertips. As content becomes a commodity, success and survival aren't about who knows the most, but who is better able to explore the unknown, actively applying and extending knowledge through critical thinking and hypothesis-driven problem-solving. This applies to the economic livelihoods of individuals and to society at large as we grapple with climate change and other science-infused challenges. Unfortunately, science is too often taught as an encyclopedic collection of settled facts to be mastered rather than as a process of exploration that embraces curiosity, inquiry, testing, and communication to reduce uncertainty about the unknown. This problem is exacerbated by the continued prevalence of teacher-centric pedagogy, which promotes learning-from-authority and passive learning. The initial wave of massively open online courses (MOOCs) generally mimic this teaching style in virtual form. It is hypothesized that emerging digital teaching technologies can help address this challenge at Internet scale in "next generation" MOOCs and flipped classroom experiences. Interactive simulations, immersive virtual field trips, gamified elements, rapid adaptive feedback, intelligent tutoring systems, and personalized pathways, should motivate and enhance learning. Through lab-like projects and tutorials, students should be able to construct knowledge from interactive experiences, modeling the authentic practice of science while mastering complex concepts. Freed from lecturing, teaching staff should be available for direct and intense student-teacher interactions. These claims are difficult to evaluate with traditional assessment instruments, but digital technologies provide powerful new ways to evaluate student learning and learn from student behaviors. We will describe ongoing experiences with such

  16. Levinas and the Mission of Education (United States)

    Zhao, Guoping


    The current educational discourse on Emmanuel Levinas's concept of subjectivity has focused on the pure openness and subjection of the self to the other. Based on such an understanding, some educational theorists hold that Levinas's work has given us new hope for the mission of education, while others deny its relevance. I suggest that this…

  17. A Neptune Orbiter Mission (United States)

    Wallace, R. A.; Spilker, T. R.


    This paper describes the results of new analyses and mission/system designs for a low cost Neptune Orbiter mission. Science and measurement objectives, instrumentation, and mission/system design options are described and reflect an aggressive approach to the application of new advanced technologies expected to be available and developed over the next five to ten years.

  18. Mission operations management (United States)

    Rocco, David A.


    Redefining the approach and philosophy that operations management uses to define, develop, and implement space missions will be a central element in achieving high efficiency mission operations for the future. The goal of a cost effective space operations program cannot be realized if the attitudes and methodologies we currently employ to plan, develop, and manage space missions do not change. A management philosophy that is in synch with the environment in terms of budget, technology, and science objectives must be developed. Changing our basic perception of mission operations will require a shift in the way we view the mission. This requires a transition from current practices of viewing the mission as a unique end product, to a 'mission development concept' built on the visualization of the end-to-end mission. To achieve this change we must define realistic mission success criteria and develop pragmatic approaches to achieve our goals. Custom mission development for all but the largest and most unique programs is not practical in the current budget environment, and we simply do not have the resources to implement all of our planned science programs. We need to shift our management focus to allow us the opportunity make use of methodologies and approaches which are based on common building blocks that can be utilized in the space, ground, and mission unique segments of all missions.


    Indian Academy of Sciences (India)

    in the Deccan Volcanic Province. 505. Ascent trajectory. Launch strategy for Indian lunar mission and precision injection to the Moon using genetic algorithm. 711 ... Space operation system for Chang'E program and its capability evaluation. 795. Chang'E-1. Scientific objectives and payloads of Chang'E-1 lunar satellite.

  20. Computer graphics aid mission operations. [NASA missions (United States)

    Jeletic, James F.


    The application of computer graphics techniques in NASA space missions is reviewed. Telemetric monitoring of the Space Shuttle and its components is discussed, noting the use of computer graphics for real-time visualization problems in the retrieval and repair of the Solar Maximum Mission. The use of the world map display for determining a spacecraft's location above the earth and the problem of verifying the relative position and orientation of spacecraft to celestial bodies are examined. The Flight Dynamics/STS Three-dimensional Monitoring System and the Trajectroy Computations and Orbital Products System world map display are described, emphasizing Space Shuttle applications. Also, consideration is given to the development of monitoring systems such as the Shuttle Payloads Mission Monitoring System and the Attitude Heads-Up Display and the use of the NASA-Goddard Two-dimensional Graphics Monitoring System during Shuttle missions and to support the Hubble Space Telescope.

  1. Management of neuroendocrine tumors of unknown primary. (United States)

    Alexandraki, Krystallenia; Angelousi, Anna; Boutzios, Georgios; Kyriakopoulos, Georgios; Rontogianni, Dimitra; Kaltsas, Gregory


    Neuroendocrine neoplams (NENs) are mostly relatively indolent malignancies but a significant number have metastatic disease at diagnosis mainly to the liver. Although in the majority of such cases the primary origin of the tumor can be identified, in approximately 11-22% no primary tumor is found and such cases are designated as NENs of unknown primary origin (UPO). This has significant therapeutic implications with respect to potentially resectable hepatic disease and/or application of appropriate medical therapy, either chemotherapeutic agents or targeted treatment, as the response to various treatments varies according to the origin of the primary tumor. This lack of tumor specific orientated treatment may also account for the relatively poorer prognosis of NENs of UPO compared to metastatic NENs with a known primary site. In the majority of cases the primary tumors are located in the small bowel and the lung, but a number may still elude detection. Occasionally the presence of a functional syndrome may direct to the specific tissue of origin but in the majority of cases a number of biochemical, imaging, histopathological and molecular modalities are utilized to help identify the primary origin of the tumor and direct treatment accordingly. Several diagnostic algorithms have recently been developed to help localize an occult primary tumor; however, in a number of cases no lesion is identified even after prolonged follow-up. It is expected that the delineation of the molecular signature of the different NENs may help identify such cases and provide appropriate treatment.

  2. Analysing Trust Transitivity and The Effects of Unknown Dependence

    Directory of Open Access Journals (Sweden)

    Touhid Bhuiyan


    Full Text Available Trust can be used to improve online automated recommendation within a given domain. Trust transitivity is used to make it successful. But trust transitivity has different interpretations. Trust and trust transitivity; both are the human mental phenomenon and for this reason, there is no such thing as objective transitivity. Trust transitivity and trust fusion both are important elements in computational trust. This paper analyses the parameter dependence problem in trust transitivity and proposes some definitions considering the effects of base rate. In addition, it also proposes belief functions based on subjective logic to analyse trust transitivity of three specified cases with sensitive and insensitive based rate. Then it presents a quantitative analysis of the effects of unknown dependence problem in an interconnected network environment; such Internet.

  3. Reconnaissance mission planning (United States)

    Fishell, Wallace G.; Fox, Alex J.


    As ATARS evolves along with its various applications, as Recce UAVs evolve to mix with manned systems, and as older systems evolve through upgrades, so should their mission planning tools evolve. To simply state that today's tactical mission planning systems will be upgraded with provisions for Reconnaissance Mission Planning completely eliminates the natural learning curve required to mature the requirements and specifications for reconnaissance planning capabilities. This paper presents MSS II lessons learned at Operation Desert Storm and briefly looks at some of the required Reconnaissance Mission Planning functions attainable through the adaptation of existing mission planning products.

  4. French pharmacovigilance: Missions, organization and perspectives. (United States)

    Vial, Thierry


    Pharmacovigilance aims to identify unknown adverse drug reactions once clinical development is complete, in order to promote improved use of drugs, and thus a reduction in risk for every exposed patient. We describe in this article the missions of French pharmacovigilance system, including French drug agency, Regional Centers of Pharmacovigilance, health professionals, pharmaceutical companies, patients and their associations. We also develop the French pharmacovigilance organization, its perspectives and challenges, both in French and European levels. Copyright © 2016. Published by Elsevier Masson SAS.

  5. Estimation of symmetrical components and their orthogonal components under unknown frequencies and unknown biases (United States)

    Chu, Zhaobi; Zhang, Rui; Chen, Bo; Li, Hua


    An algorithm to estimate symmetrical components, orthogonal components and amplitudes of each sinusoidal component in three-phase power system signal under unknown frequencies and unknown biases is presented. The algorithm consists of a signal transformation, a biased adaptive orthogonal decomposition (BAOD) and a symmetrical component estimation. The BAOD can be regarded as a combination of a low pass filter and a number of three-phase frequency estimators in parallel. The symmetrical component estimation employs addition and multiplication rather than operations of trigonometry, division and phase shift. The decomposition property and the convergence property were investigated by Lyapunov theorem, integral manifold of slow adaptation and average method. Two design parameters, bandwidth parameter and frequency adaptive gains, give different effects on the convergence property of frequency adaptation and amplitude estimation independently. Simulation results demonstrate the performance of the method.

  6. The STEREO Mission

    CERN Document Server


    The STEREO mission uses twin heliospheric orbiters to track solar disturbances from their initiation to 1 AU. This book documents the mission, its objectives, the spacecraft that execute it and the instruments that provide the measurements, both remote sensing and in situ. This mission promises to unlock many of the mysteries of how the Sun produces what has become to be known as space weather.

  7. Juno Mission Simulation (United States)

    Lee, Meemong; Weidner, Richard J.


    The Juno spacecraft is planned to launch in August of 2012 and would arrive at Jupiter four years later. The spacecraft would spend more than one year orbiting the planet and investigating the existence of an ice-rock core; determining the amount of global water and ammonia present in the atmosphere, studying convection and deep- wind profiles in the atmosphere; investigating the origin of the Jovian magnetic field, and exploring the polar magnetosphere. Juno mission management is responsible for mission and navigation design, mission operation planning, and ground-data-system development. In order to ensure successful mission management from initial checkout to final de-orbit, it is critical to share a common vision of the entire mission operation phases with the rest of the project teams. Two major challenges are 1) how to develop a shared vision that can be appreciated by all of the project teams of diverse disciplines and expertise, and 2) how to continuously evolve a shared vision as the project lifecycle progresses from formulation phase to operation phase. The Juno mission simulation team addresses these challenges by developing agile and progressive mission models, operation simulations, and real-time visualization products. This paper presents mission simulation visualization network (MSVN) technology that has enabled a comprehensive mission simulation suite (MSVN-Juno) for the Juno project.

  8. Expanding subjectivities

    DEFF Research Database (Denmark)

    Lundgaard Andersen, Linda; Soldz, Stephen


    A major theme in recent psychoanalytic thinking concerns the use of therapist subjectivity, especially “countertransference,” in understanding patients. This thinking converges with and expands developments in qualitative research regarding the use of researcher subjectivity as a tool to understa...

  9. Bering Mission Navigation Method

    DEFF Research Database (Denmark)

    Betto, Maurizio; Jørgensen, John Leif; Jørgensen, Peter Siegbjørn


    "Bering", after the name of the famous Danish explorer, is a near Earth object (NEO) and main belt asteroids mapping mission envisaged by a consortium of Danish universities and research institutes. To achieve the ambitious goals set forth by this mission, while containing the costs and risks...

  10. The Pioneer Venus Missions. (United States)

    National Aeronautics and Space Administration, Mountain View, CA. Ames Research Center.

    This document provides detailed information on the atmosphere and weather of Venus. This pamphlet describes the technological hardware including the probes that enter the Venusian atmosphere, the orbiter and the launch vehicle. Information is provided in lay terms on the mission profile, including details of events from launch to mission end. The…

  11. KEEL for Mission Planning (United States)


    if the Mission Planning Software is supporting human planners. Copyright 2016, Compsim, All Rights Reserved 5 KEEL Operational Policy...cognitive technology for application in automotive, industrial automation, medical, military, governmental, enterprise software and electronic gaming... Copyright 2016, Compsim, All Rights Reserved 1 KEEL® Technology in support of Mission Planning and Execution delivering Adaptive

  12. Control design for the SISO system with the unknown order and the unknown relative degree. (United States)

    Zhao, Chunzhe; Li, Donghai


    For the uncertain system whose order, relative degree and parameters are unknown in the control design, new research is still in need on the parameter tuning and close-loop stability. During the last 10 years, much progress is made in the application and theory research of the active disturbance rejection control (ADRC) for the uncertain system. In this study, the necessary and sufficient conditions are established for building the ADRC for the minimum-phase system and the open-loop stable system when the plant parameters, orders and relative degrees are unknown, the corresponding ideal dynamics are analyzed, and the theoretical results are verified by the simulations. Considering the wide application and the long history of the PID/PI controller, a method is given to design ADRC quickly based on the existing (generalized or conventional) PID/PI controller. A plenty of simulations are made to illustrate this PID/PI-based design method and the corresponding close-loop performances. The simulation examples include the minimum/nonminimum-phase plants, the stable/integrating plants, the high/low-order plant, and the plants with time delays. Such plants are from a wider scope than the theoretical result, and representative of many kinds of the industrial processes. That leads to a new way to simplify the ADRC design via absorbing the engineering experience in designing the PID/PI controller. © 2013 ISA. Published by ISA. All rights reserved.

  13. Reliability of mechanical trunk responses during known and unknown trunk perturbations

    DEFF Research Database (Denmark)

    Jakobsen, Markus D.; Brandt, Mikkel; Sundstrup, Emil


    This study evaluates the between-day reliability of a newly developed trunk perturbation test and compares mechanical response during known and unknown conditions. Mechanical trunk response were measured in seventeen female subjects during unloading and loading perturbations of the abdomen (A: pr...

  14. The Unknown Story: Vocational Education for Adults in Sweden 1918-1968 (United States)

    Nilsson, Anders


    Adult education is often defined to emphasise cultural and societal development. This paper proposes that the concept should be more inclusive and that vocational education and training for adults has played a bigger role than is usually recognised. This has not been subject to much research and basic facts are often virtually unknown. In this…

  15. Research advances in liver failure of unknown etiology

    Directory of Open Access Journals (Sweden)

    ZHU Bing


    Full Text Available A high proportion of the causes of liver failure remain unknown. This paper reviews the progress in the epidemiology, etiology, treatment, and prognosis of liver failure of unknown etiology. The possible causes of liver failure of unknown etiology may include occult hepatitis B virus infection, herpesvirus infection, transfusion-transmitted virus infection, hepatitis G virus infection, human parvovirus Bl9 infection, autoimmune and hepatitis. Aciclovir can be considered in the empirical treatment for patients with liver failure of unknown etiology. The mortality in patients with liver failure of unknown etiology is high. The research on the etiology and treatments should be strengthened.

  16. Hipparcos: mission accomplished (United States)


    prime contractor was Matra Marconi Space (France), also responsible for the payload and the on-board software development: with Alenia (Italy) responsible for the procurement of the spacecraft, as well as integration and testing of the complete satellite. A total of 35 European firms were involved in the satellite construction. The satellite was launched by Ariane 4 on 8 August 1989. Hipparcos was named after the pioneer Greek astronomer Hipparchus who compiled a detailed star map in around 120 BC and, by comparing it with observations made by his predecessors, established that the Earth's rotation axis slowly changed its direction in space. The Hipparcos satellite carried out its measurements in a highly elliptical 10-hour orbit, ranging between 500 km and 36,000 km above the Earth's surface, resulting from non-functioning of the satellite's apogee boost motor shortly after launch. A redesign of the on-board attitude control system, and the addition of two more ground stations into the control network, nevertheless allowed ESA's operations team at ESOC (Darmstadt, Germany) to operate the satellite with close to full efficiency. For the 20-strong operations team at ESOC and the ground station teams in Perth (Australia), Goldstone (USA) and Kourou (French Guiana) the mission has been highly interesting, challenging and very demanding. "After more than three years of excellent performance, underlining the remarkable quality of the satellite's design and construction, it was showing its age in several areas" said Dietmar Heger, ESOC's Spacecraft Operations Manager for Hipparcos. "The orbit was subjected to very significant levels of high energy electron and proton radiation, much higher than those expected in its intended geostationary orbit. We cannot be surprised or disappointed that the satellite has finally ceased to function" he said. The scientific activities associated with the Hipparcos mission are under the responsibility of four European scientific teams

  17. Identification of an unknown extraneous contaminant in pharmaceutical product analysis. (United States)

    Lin, Mingxiang; Li, Min; Rustum, Abu


    During the content uniformity test of a drug product (tablet formulation), an unknown peak was observed in the HPLC chromatograms. Upon further investigation, it was determined that the unknown peak was originated from an external source and, therefore, the drug product is free of this unknown peak. The next step was to identify the structure of this unknown peak in order to determine the source of this contaminant species. In this paper, we wish to present the strategy and the results of the experiments that led to the identification of this unknown peak. LC-PDA/UV and LC-MS(n) analyses were conducted to obtain the UV spectrum, molecular weight and MS(n) fragmentation pathways of the unknown peak. The MS analysis revealed certain structural features of the unknown species and a number of model compounds that contain such features were then examined for their UV absorbance profiles in an attempt to establish the functional group connectivity within the unknown species. A careful examination of these results in conjunction with the determination of the high-resolution molecular weight led to a short list of potential candidates for the unknown species, among which the most likely one was 1,3-diphenylguanidine. The identification of the unknown contaminant was confirmed by spiking experiments using the authentic compound. The potential source of this contaminant was also identified as derived from the safety filler of the pipette bulb used to prepare the sample solutions during the drug analysis.

  18. STS-65 Mission Onboard Photograph (United States)


    In this photograph, astronaut Carl Walz performs the Performance Assessment Workstation (PAWS) experiment at the flight deck of the Space Shuttle Orbiter Columbia during the STS-65 mission. Present day astronauts are subject to a variety of stresses during spaceflight. These include microgravity, physical isolation, confinement, lack of privacy, fatigue, and changing work/rest cycles. The purpose of this experiment is to determine the effects of microgravity upon thinking skills critical to the success of operational tasks in space. The principle objective is to distinguish between the effects of microgravity on specific information-processing skills affecting performance and those of fatigue caused by long work periods. To measure these skills, the investigators use a set of computerized performance tests called the Performance Assessment Workstation, which is based on current theoretical models of human performance. The tests were selected by analyzing tasks related to space missions and their hypothesized sensitivity to microgravity. Multiple subjective measures of cumulative fatigue and changing mood states are also included for interpreting performance data.

  19. Connecting second language learning and nonlinguistic subjects mission impossible?

    Directory of Open Access Journals (Sweden)

    Andreja Retelj, Karmen Pižorn


    Full Text Available Content based language learning as a second language learning approach that has spread in Europe and in several countries became a part of the national curriculum, has in Slovenia not yet been formally established and is present only in the form of pilot projects. It includes a set of different teaching approaches and methods which combine two objec tives: focus on language and focus on content. Such ways of second language learning not only increase the student's language skills, but also affect his cognitive development. Given the added value that these approaches provide to the student, from practical use of second language to familiarizing with language diversity through all his schooling, we should find solutions for its implementation in Slovenian school system.


    Indian Academy of Sciences (India)

    Subject Index. Variation of surface electric field during geomagnetic disturbed period at Maitri, Antarctica. 1721. Geomorphology. A simple depression-filling method for raster and irregular elevation datasets. 1653. Decision Support System integrated with Geographic. Information System to target restoration actions in water-.

  1. Uganda Mission PRS (United States)

    US Agency for International Development — A web-based performance reporting system that is managed by IBI that interfaces with the Mission's GIS database that supports USAID/Uganda and its implementing...

  2. STS-83 Mission Insignia (United States)


    The crew patch for NASA's STS-83 mission depicts the Space Shuttle Columbia launching into space for the first Microgravity Sciences Laboratory 1 (MSL-1) mission. MSL-1 investigated materials science, fluid dynamics, biotechnology, and combustion science in the microgravity environment of space, experiments that were conducted in the Spacelab Module in the Space Shuttle Columbia's cargo bay. The center circle symbolizes a free liquid under microgravity conditions representing various fluid and materials science experiments. Symbolic of the combustion experiments is the surrounding starburst of a blue flame burning in space. The 3-lobed shape of the outermost starburst ring traces the dot pattern of a transmission Laue photograph typical of biotechnology experiments. The numerical designation for the mission is shown at bottom center. As a forerunner to missions involving International Space Station (ISS), STS-83 represented the hope that scientific results and knowledge gained during the flight will be applied to solving problems on Earth for the benefit and advancement of humankind.

  3. Autonomous Mission Operations Project (United States)

    National Aeronautics and Space Administration — Future human spaceflight missions will occur with crews and spacecraft at large distances, with long communication delays, to the Earth. The one-way light-time delay...

  4. Colombia: Updating the Mission (United States)


    or La Violencia . Bogota was nearly destroyed, and the bloodshed spilled into the countryside where it reached its greatest intensity. The machete...role and its commitment to its assigned mission. Army Mission During La Violencia (1948–1962) Of course, it is the army that we are par- ticularly...result was Colombia’s costli- est civil war, termed simply The Violence, or La Violencia . Bogota was nearly destroyed, and the bloodshed spilled into

  5. Crewmember and mission control personnel interactions during International Space Station missions. (United States)

    Kanas, Nick A; Salnitskiy, Vyacheslav P; Boyd, Jennifer E; Gushin, Vadim I; Weiss, Daniel S; Saylor, Stephanie A; Kozerenko, Olga P; Marmar, Charles R


    Reports from astronauts and cosmonauts, studies from space analogue environments on Earth, and our previous research on the Mir Space Station have identified a number of psychosocial issues that can lead to problems during long-duration space missions. Three of these issues (time effects, displacement, leader role) were studied during a series of long-duration missions to the International Space Station (ISS). As in our previous Mir study, mood and group climate questions from the Profile of Mood States or POMS, the Group Environment Scale or GES, and the Work Environment Scale or WES were completed weekly by 17 ISS crewmembers (15 men, 2 women) in space and 128 American and Russian personnel in mission control. The results did not support the presence of decrements in mood and group cohesion during the 2nd half of the missions or in any specific quarter. The results did support the predicted displacement of negative feelings to outside supervisors in both crew and mission control subjects on all six questionnaire subscales tested. Crewmembers related cohesion in their group to the support role of their commander. For mission control personnel, greater cohesion was linked to the support role as well as to the task role of their leader. The findings from our previous study on the Mir Space Station were essentially replicated on board the ISS. The findings suggest a number of countermeasures for future on-orbit missions, some of which may not be relevant for expeditionary missions (e.g., to Mars).

  6. Robotic Mission Simulation Tool Project (United States)

    National Aeronautics and Space Administration — Energid Technologies proposes a software tool to predict robotic mission performance and support supervision of robotic missions even when environments and...

  7. Precipitation Measurement Missions Data Access (United States)

    National Aeronautics and Space Administration — Tropical Rainfall Measuring Mission (TRMM) data products are currently available from 1998 to the present. Global Precipitation Measurement (GPM) mission data...

  8. 16 CFR 303.14 - Products containing unknown fibers. (United States)


    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Products containing unknown fibers. 303.14... RULES AND REGULATIONS UNDER THE TEXTILE FIBER PRODUCTS IDENTIFICATION ACT § 303.14 Products containing unknown fibers. (a) Where a textile fiber product is made from miscellaneous scraps, rags, odd lots...

  9. 37 CFR 381.9 - Unknown copyright owners. (United States)


    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Unknown copyright owners. 381.9 Section 381.9 Patents, Trademarks, and Copyrights COPYRIGHT ROYALTY BOARD, LIBRARY OF CONGRESS... EDUCATIONAL BROADCASTING § 381.9 Unknown copyright owners. If PBS and its stations, NPR and its stations, or...

  10. 37 CFR 253.9 - Unknown copyright owners. (United States)


    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Unknown copyright owners. 253.9 Section 253.9 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT... NONCOMMERCIAL EDUCATIONAL BROADCASTING § 253.9 Unknown copyright owners. If PBS and its stations, NPR and its...

  11. 37 CFR 382.7 - Unknown copyright owners. (United States)


    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Unknown copyright owners. 382.7 Section 382.7 Patents, Trademarks, and Copyrights COPYRIGHT ROYALTY BOARD, LIBRARY OF CONGRESS... SATELLITE DIGITAL AUDIO RADIO SERVICES Preexisting Subscription Services § 382.7 Unknown copyright owners...

  12. 37 CFR 260.7 - Unknown copyright owners. (United States)


    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Unknown copyright owners. 260.7 Section 260.7 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT... TRANSMISSIONS OF SOUND RECORDINGS AND MAKING OF EPHEMERAL PHONORECORDS § 260.7 Unknown copyright owners. If the...

  13. Unknown Input Observer Design for Fuzzy Bilinear System: An LMI Approach

    Directory of Open Access Journals (Sweden)

    D. Saoudi


    Full Text Available A new method to design a fuzzy bilinear observer (FBO with unknown inputs is developed for a class of nonlinear systems. The nonlinear system is modeled as a fuzzy bilinear model (FBM. This kind of T-S fuzzy model is especially suitable for a nonlinear system with a bilinear term. The proposed fuzzy bilinear observer subject to unknown inputs is developed to ensure the asymptotic convergence of the error dynamic using the Lyapunov method. The proposed design conditions are given in linear matrix inequality (LMI formulation. The paper studies also the problem of fault detection and isolation. An unknown input fuzzy bilinear fault diagnosis observer design is proposed. This work is given for both continuous and discrete cases of fuzzy bilinear models. Illustrative examples are chosen to provide the effectiveness of the given methodology.

  14. Sentinel-2 mission status (United States)

    Hoersch, Bianca


    The SENTINEL-2 mission is the European Multispectral Imaging Mission for the Copernicus joint initiative of the European Commission (EC) and the European Space Agency (ESA). The SENTINEL-2 mission includes 13-spectral band multispectral optical imager with different resolution (down to 10 m) and a swath width of 290km. It provides very short revisit times and rapid product delivery. The mission is composed of a constellation of two satellite units, SENTINEL-2A and SENTINEL-2B, sharing the same orbital plane and featuring a short repeat cycle of 5 days at the equator optimized to mitigate the impact of clouds for science and applications. SENTINEL-2 enables exploitation for a variety of land and coastal applications such as agriculture, forestry, land cover and land cover change, urban mapping, emergency, as well as inland water, ice, glaciers and also coastal zone and closed seas applications. Following the launch of the Sentinel-2A in June 2015 and successful operations and data delivery since December 2015, the Sentinel-2B satellite is set for launch in March 2017. The full operation capacity is foreseen after the in-orbit commissioning phase of the Sentinel-2B unit in early summer 2017. The objective of the talk is to provide information about the mission status, and the way to achieve full operational capacity with 2 satellites.

  15. Epidemic renal disease of unknown etiology in the Zuni Indians

    Energy Technology Data Exchange (ETDEWEB)

    Hoy, W.E.; Megill, D.M.; Hughson, M.D.


    An epidemic of renal disease is occurring among the Zuni Indians in western New Mexico. In 1985, 1.6% of Zunis had clinically recognized renal disease and 1% had renal insufficiency. The incidence of end-stage renal disease (ESRD) in 1984 and 1985 was 14 times the rate for US whites, and three times the rates of other Indians in ESRD network 6. One third of the cases of renal disease and ESRD is due to type 2 diabetes, but the etiology of disease in most of the remainder is unknown. Affected subjects range from early childhood to old age. Early signs are hematuria, mild to moderate proteinuria, normal BP, and low total hemolytic complement, normal or low C3 and C4 levels, in about 40% of the cases. The clinical course varies from benign to rapidly progressive renal failure. Biopsies usually reflect an immune-complex mediated mesangiopathic glomerulonephritis, with IgA, IgG, IgM, and C3 variably present in the mesangium. In some cases, there is a very strong familial pattern suggesting autosomal dominant inheritance or a marked communal exposure effect. This may be a genetic disease educed by the consanguinity in the ethnically homogeneous Zuni population. Mesangiopathic renal disease is common in some Oriental populations, and this phenomenon may reflect the American Indians' Oriental ancestry. This disease may also be due to toxic exposures related to jewelry-making, potting, Zuni water, Zuni salt, or herbal or other products used for medicinal or religious purposes. This epidemic is causing much morbidity and generating huge costs for ESRD treatment. Further study is needed to better understand its etiology.

  16. The Hinode Mission

    CERN Document Server

    Sakurai, Takashi


    The Solar-B satellite was launched in 2006 by the Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (ISAS/JAXA), and was renamed Hinode ('sunrise' in Japanese). Hinode carries three instruments: the X-ray telescope (XRT), the EUV imaging spectrometer (EIS), and the Solar Optical Telescope (SOT). These instruments were developed by ISAS/JAXA in cooperation with the National Astronomical Observatory of Japan as domestic partner, and NASA and the Science and Technology Facilities Council (UK) as international partners. ESA and the Norwegian Space Center have been providing a downlink station. The Hinode (Solar-B) Mission gives a comprehensive description of the Hinode mission and its instruments onboard. This book is most useful for researchers, professionals, and graduate students working in the field of solar physics, astronomy, and space instrumentation. This is the only book that carefully describes the details of the Hinode mission; it is richly illustrated with full-color ima...

  17. STS-95 Mission Insignia (United States)


    The STS-95 patch, designed by the crew, is intended to reflect the scientific, engineering, and historic elements of the mission. The Space Shuttle Discovery is shown rising over the sunlit Earth limb, representing the global benefits of the mission science and the solar science objectives of the Spartan Satellite. The bold number '7' signifies the seven members of Discovery's crew and also represents a historical link to the original seven Mercury astronauts. The STS-95 crew member John Glenn's first orbital flight is represented by the Friendship 7 capsule. The rocket plumes symbolize the three major fields of science represented by the mission payloads: microgravity material science, medical research for humans on Earth and in space, and astronomy.

  18. Athena Mission Status (United States)

    Lumb, D.


    Athena has been selected by ESA for its second large mission opportunity of the Cosmic Visions programme, to address the theme of the Hot and Energetic Universe. Following the submission of a proposal from the community, the technical and programmatic aspects of the mission design were reviewed in ESA's Concurrent Design Facility. The proposed concept was deemed to betechnically feasible, but with potential constraints from cost and schedule. Two parallel industry study contracts have been conducted to explore these conclusions more thoroughly, with the key aim of providing consolidated inputs to a Mission Consolidation Review that was conducted in April-May 2016. This MCR has recommended a baseline design, which allows the agency to solicit proposals for a community provided payload. Key design aspects arising from the studies are described, and the new reference design is summarised.

  19. Supporting the academic mission. (United States)

    Dunnick, N Reed


    The mission of an academic radiology department includes not only high-quality patient care, but also the educating of a broad variety of health care professionals, the conducting of research to advance the field, and volunteering service to the medical center and our professional societies. While funding is available for the research and educational aspects, it is insufficient to cover the actual costs. Furthermore, it is becoming increasingly difficult to make up the deficit by using a portion of the clinical revenues. Development and revenues derived from intellectual property are becoming essential to support the academic mission.

  20. MIV Project: Mission scenario

    DEFF Research Database (Denmark)

    Ravazzotti, Mariolina T.; Jørgensen, John Leif; Thuesen, Gøsta


    Under the ESA contract #11453/95/NL/JG(SC), aiming at assessing the feasibility of Rendez-vous and docking of unmanned spacecrafts, a msiision scenario was defined. This report describes the secquence of manouvres and task allocations for such missions.......Under the ESA contract #11453/95/NL/JG(SC), aiming at assessing the feasibility of Rendez-vous and docking of unmanned spacecrafts, a msiision scenario was defined. This report describes the secquence of manouvres and task allocations for such missions....

  1. The Euromir missions. (United States)

    Andresen, R D; Domesle, R


    The 179-day flight of ESA Astronaut Thomas Reiter onboard the Russian Space Station Mir drew to a successful conclusion on 29 February 1996 with the safe landing of the Soyuz TM-22 capsule near Arkalyk in Kazakhstan. This mission, known as Euromir 95, was part of ESA's precursor flight programme for the International Space Station, and followed the equally successful Euromir 94 mission by ESA Astronaut Ulf Merbold (3 October-4 November 1994). This article discusses the objectives of the two flights and presents an overview of the experiment programme, a preliminary assessment of its results and achievements, and reviews some of the lessons learnt for future Space Station operations.

  2. Mars Stratigraphy Mission (United States)

    Budney, C. J.; Miller, S. L.; Cutts, J. A.


    The Mars Stratigraphy Mission lands a rover on the surface of Mars which descends down a cliff in Valles Marineris to study the stratigraphy. The rover carries a unique complement of instruments to analyze and age-date materials encountered during descent past 2 km of strata. The science objective for the Mars Stratigraphy Mission is to identify the geologic history of the layered deposits in the Valles Marineris region of Mars. This includes constraining the time interval for formation of these deposits by measuring the ages of various layers and determining the origin of the deposits (volcanic or sedimentary) by measuring their composition and imaging their morphology.

  3. Using Natural Language to Enhance Mission Effectiveness (United States)

    Trujillo, Anna C.; Meszaros, Erica


    The availability of highly capable, yet relatively cheap, unmanned aerial vehicles (UAVs) is opening up new areas of use for hobbyists and for professional-related activities. The driving function of this research is allowing a non-UAV pilot, an operator, to define and manage a mission. This paper describes the preliminary usability measures of an interface that allows an operator to define the mission using speech to make inputs. An experiment was conducted to begin to enumerate the efficacy and user acceptance of using voice commands to define a multi-UAV mission and to provide high-level vehicle control commands such as "takeoff." The primary independent variable was input type - voice or mouse. The primary dependent variables consisted of the correctness of the mission parameter inputs and the time needed to make all inputs. Other dependent variables included NASA-TLX workload ratings and subjective ratings on a final questionnaire. The experiment required each subject to fill in an online form that contained comparable required information that would be needed for a package dispatcher to deliver packages. For each run, subjects typed in a simple numeric code for the package code. They then defined the initial starting position, the delivery location, and the return location using either pull-down menus or voice input. Voice input was accomplished using CMU Sphinx4-5prealpha for speech recognition. They then inputted the length of the package. These were the option fields. The subject had the system "Calculate Trajectory" and then "Takeoff" once the trajectory was calculated. Later, the subject used "Land" to finish the run. After the voice and mouse input blocked runs, subjects completed a NASA-TLX. At the conclusion of all runs, subjects completed a questionnaire asking them about their experience in inputting the mission parameters, and starting and stopping the mission using mouse and voice input. In general, the usability of voice commands is acceptable

  4. Designing to Sample the Unknown: Lessons from OSIRIS-REx Project Systems Engineering (United States)

    Everett, David; Mink, Ronald; Linn, Timothy; Wood, Joshua


    On September 8, 2016, the third NASA New Frontiers mission launched on an Atlas V 411. The Origins, Spectral Interpretation, Resource Identification, Security-Regolith Explorer (OSIRIS-REx) will rendezvous with asteroid Bennu in 2018, collect a sample in 2020, and return that sample to Earth in September 2023. The development team has overcome a number of challenges in order to design and build a system that will make contact with an unexplored, airless, low-gravity body. This paper will provide an overview of the mission, then focus in on the system-level challenges and some of the key system-level processes. Some of the lessons here are unique to the type of mission, like discussion of operating at a largely-unknown, low-gravity object. Other lessons, particularly from the build phase, have broad implications. The OSIRIS-REx risk management process was particularly effective in achieving an on-time and under-budget development effort. The systematic requirements management and verification and the system validation also helped identify numerous potential problems. The final assessment of the OSIRIS-REx performance will need to wait until the sample is returned in 2023, but this post-launch assessment will capture some of the key systems-engineering lessons from the development team.

  5. Grasping Unknown Objects in an Early Cognitive Vision System

    DEFF Research Database (Denmark)

    Popovic, Mila


    Grasping of unknown objects presents an important and challenging part of robot manipulation. The growing area of service robotics depends upon the ability of robots to autonomously grasp and manipulate a wide range of objects in everyday environments. Simple, non task-specific grasps of unknown...... presents a system for robotic grasping of unknown objects us- ing stereo vision. Grasps are defined based on contour and surface information provided by the Early Cognitive Vision System, that organizes visual informa- tion into a biologically motivated hierarchical representation. The contributions...

  6. Adaptive interferometric null testing for unknown freeform optics metrology. (United States)

    Huang, Lei; Choi, Heejoo; Zhao, Wenchuan; Graves, Logan R; Kim, Dae Wook


    We report an adaptive interferometric null testing method for overcoming the dynamic range limitations of conventional null testing approaches during unknown freeform optics metrology or optics manufacturing processes that require not-yet-completed surface measurements to guide the next fabrication process. In the presented adaptive method, a deformable mirror functions as an adaptable null component for an unknown optical surface. The optimal deformable mirror's shape is determined by the stochastic parallel gradient descent algorithm and controlled by a deflectometry system. An adaptive interferometric null testing setup was constructed, and its metrology data successfully demonstrated superb adaptive capability in measuring an unknown surface.

  7. Reference mission 3B ascent trajectory. Mission planning, mission analysis and software formulation (United States)

    Kuhn, A. E.


    Mission 3B is designed as a payload retrieval mission with both shuttle launch and orbiter landing to take place at the western test range. The mission is designed for direct rendezvous with a passive satellite in a 100 NMI circular orbit with an inclination of 104 degrees. The ascent portion of mission 3B is described as well as the trajectory simulation.

  8. Demographic window to aging in the wild: constructing life tables and estimating survival functions from marked individuals of unknown age


    Müller, Hans-Georg; Wang, Jane-Ling; Carey, James R.; Caswell-Chen, Edward P.; Chen, Carl; Papadopoulos, Nikos; Yao, Fang


    We address the problem of establishing a survival schedule for wild populations. A demographic key identity is established, leading to a method whereby age-specific survival and mortality can be deduced from a marked cohort life table established for individuals that are randomly sampled at unknown age and marked, with subsequent recording of time-to-death. This identity permits the construction of life tables from data where the birth date of subjects is unknown. An analogous key identity is...

  9. The Gaia mission

    NARCIS (Netherlands)

    Collaboration, Gaia; Prusti, T.; de Bruijne, J. H. J.; Brown, A. G. A.; Vallenari, A.; Babusiaux, C.; Bailer-Jones, C. A. L.; Bastian, U.; Biermann, M.; Evans, D. W.; Eyer, L.; Jansen, F.; Jordi, C.; Klioner, S. A.; Lammers, U.; Lindegren, L.; Luri, X.; Mignard, F.; Milligan, D. J.; Panem, C.; Poinsignon, V.; Pourbaix, D.; Randich, S.; Sarri, G.; Sartoretti, P.; Siddiqui, H. I.; Soubiran, C.; Valette, V.; van Leeuwen, F.; Walton, N. A.; Aerts, C.; Arenou, F.; Cropper, M.; Drimmel, R.; Høg, E.; Katz, D.; Lattanzi, M. G.; O'Mullane, W.; Grebel, E. K.; Holland, A. D.; Huc, C.; Passot, X.; Bramante, L.; Cacciari, C.; Castañeda, J.; Chaoul, L.; Cheek, N.; De Angeli, F.; Fabricius, C.; Guerra, R.; Hernández, J.; Jean-Antoine-Piccolo, A.; Masana, E.; Messineo, R.; Mowlavi, N.; Nienartowicz, K.; Ordóñez-Blanco, D.; Panuzzo, P.; Portell, J.; Richards, P. J.; Riello, M.; Seabroke, G. M.; Tanga, P.; Thévenin, F.; Torra, J.; Els, S. G.; Gracia-Abril, G.; Comoretto, G.; Garcia-Reinaldos, M.; Lock, T.; Mercier, E.; Altmann, M.; Andrae, R.; Astraatmadja, T. L.; Bellas-Velidis, I.; Benson, K.; Berthier, J.; Blomme, R.; Busso, G.; Carry, B.; Cellino, A.; Clementini, G.; Cowell, S.; Creevey, O.; Cuypers, J.; Davidson, M.; De Ridder, J.; de Torres, A.; Delchambre, L.; Dell'Oro, A.; Ducourant, C.; Frémat, Y.; García-Torres, M.; Gosset, E.; Halbwachs, J. -L; Hambly, N. C.; Harrison, D. L.; Hauser, M.; Hestroffer, D.; Hodgkin, S. T.; Huckle, H. E.; Hutton, A.; Jasniewicz, G.; Jordan, S.; Kontizas, M.; Korn, A. J.; Lanzafame, A. C.; Manteiga, M.; Moitinho, A.; Muinonen, K.; Osinde, J.; Pancino, E.; Pauwels, T.; Petit, J. -M; Recio-Blanco, A.; Robin, A. C.; Sarro, L. M.; Siopis, C.; Smith, M.; Smith, K. W.; Sozzetti, A.; Thuillot, W.; van Reeven, W.; Viala, Y.; Abbas, U.; Abreu Aramburu, A.; Accart, S.; Aguado, J. J.; Allan, P. M.; Allasia, W.; Altavilla, G.; Álvarez, M. A.; Alves, J.; Anderson, R. I.; Andrei, A. H.; Anglada Varela, E.; Antiche, E.; Antoja, T.; Antón, S.; Arcay, B.; Atzei, A.; Ayache, L.; Bach, N.; Baker, S. G.; Balaguer-Núñez, L.; Barache, C.; Barata, C.; Barbier, A.; Barblan, F.; Baroni, M.; Barrado y Navascués, D.; Barros, M.; Barstow, M. A.; Becciani, U.; Bellazzini, M.; Bellei, G.; Bello García, A.; Belokurov, V.; Bendjoya, P.; Berihuete, A.; Bianchi, L.; Bienaymé, O.; Billebaud, F.; Blagorodnova, N.; Blanco-Cuaresma, S.; Boch, T.; Bombrun, A.; Borrachero, R.; Bouquillon, S.; Bourda, G.; Bouy, H.; Bragaglia, A.; Breddels, M. A.; Brouillet, N.; Brüsemeister, T.; Bucciarelli, B.; Budnik, F.; Burgess, P.; Burgon, R.; Burlacu, A.; Busonero, D.; Buzzi, R.; Caffau, E.; Cambras, J.; Campbell, H.; Cancelliere, R.; Cantat-Gaudin, T.; Carlucci, T.; Carrasco, J. M.; Castellani, M.; Charlot, P.; Charnas, J.; Charvet, P.; Chassat, F.; Chiavassa, A.; Clotet, M.; Cocozza, G.; Collins, R. S.; Collins, P.; Costigan, G.; Crifo, F.; Cross, N. J. G.; Crosta, M.; Crowley, C.; Dafonte, C.; Damerdji, Y.; Dapergolas, A.; David, P.; David, M.; De Cat, P.; de Felice, F.; de Laverny, P.; De Luise, F.; De March, R.; de Martino, D.; de Souza, R.; Debosscher, J.; del Pozo, E.; Delbo, M.; Delgado, A.; Delgado, H. E.; di Marco, F.; Di Matteo, P.; Diakite, S.; Distefano, E.; Dolding, C.; Dos Anjos, S.; Drazinos, P.; Durán, J.; Dzigan, Y.; Ecale, E.; Edvardsson, B.; Enke, H.; Erdmann, M.; Escolar, D.; Espina, M.; Evans, N. W.; Eynard Bontemps, G.; Fabre, C.; Fabrizio, M.; Faigler, S.; Falcão, A. J.; Farràs Casas, M.; Faye, F.; Federici, L.; Fedorets, G.; Fernández-Hernández, J.; Fernique, P.; Fienga, A.; Figueras, F.; Filippi, F.; Findeisen, K.; Fonti, A.; Fouesneau, M.; Fraile, E.; Fraser, M.; Fuchs, J.; Furnell, R.; Gai, M.; Galleti, S.; Galluccio, L.; Garabato, D.; García-Sedano, F.; Garé, P.; Garofalo, A.; Garralda, N.; Gavras, P.; Gerssen, J.; Geyer, R.; Gilmore, G.; Girona, S.; Giuffrida, G.; Gomes, M.; González-Marcos, A.; González-Núñez, J.; González-Vidal, J. J.; Granvik, M.; Guerrier, A.; Guillout, P.; Guiraud, J.; Gúrpide, A.; Gutiérrez-Sánchez, R.; Guy, L. P.; Haigron, R.; Hatzidimitriou, D.; Haywood, M.; Heiter, U.; Helmi, A.; Hobbs, D.; Hofmann, W.; Holl, B.; Holland, G.; Hunt, J. A. S.; Hypki, A.; Icardi, V.; Irwin, M.; Jevardat de Fombelle, G.; Jofré, P.; Jonker, P. G.; Jorissen, A.; Julbe, F.; Karampelas, A.; Kochoska, A.; Kohley, R.; Kolenberg, K.; Kontizas, E.; Koposov, S. E.; Kordopatis, G.; Koubsky, P.; Kowalczyk, A.; Krone-Martins, A.; Kudryashova, M.; Kull, I.; Bachchan, R. K.; Lacoste-Seris, F.; Lanza, A. F.; Lavigne, J. -B; Le Poncin-Lafitte, C.; Lebreton, Y.; Lebzelter, T.; Leccia, S.; Leclerc, N.; Lecoeur-Taibi, I.; Lemaitre, V.; Lenhardt, H.; Leroux, F.; Liao, S.; Licata, E.; Lindstrøm, H. E. P.; Lister, T. A.; Livanou, E.; Lobel, A.; Löffler, W.; López, M.; Lopez-Lozano, A.; Lorenz, D.; Loureiro, T.; MacDonald, I.; Magalhães Fernandes, T.; Managau, S.; Mann, R. G.; Mantelet, G.; Marchal, O.; Marchant, J. M.; Marconi, M.; Marie, J.; Marinoni, S.; Marrese, P. M.; Marschalkó, G.; Marshall, D. J.; Martín-Fleitas, J. M.; Martino, M.; Mary, N.; Matijevič, G.; Mazeh, T.; McMillan, P. J.; Messina, S.; Mestre, A.; Michalik, D.; Millar, N. R.; Miranda, B. M. H.; Molina, D.; Molinaro, R.; Molinaro, M.; Molnár, L.; Moniez, M.; Montegriffo, P.; Monteiro, D.; Mor, R.; Mora, A.; Morbidelli, R.; Morel, T.; Morgenthaler, S.; Morley, T.; Morris, D.; Mulone, A. F.; Muraveva, T.; Musella, I.; Narbonne, J.; Nelemans, G.; Nicastro, L.; Noval, L.; Ordénovic, C.; Ordieres-Meré, J.; Osborne, P.; Pagani, C.; Pagano, I.; Pailler, F.; Palacin, H.; Palaversa, L.; Parsons, P.; Paulsen, T.; Pecoraro, M.; Pedrosa, R.; Pentikäinen, H.; Pereira, J.; Pichon, B.; Piersimoni, A. M.; Pineau, F. -X; Plachy, E.; Plum, G.; Poujoulet, E.; Prša, A.; Pulone, L.; Ragaini, S.; Rago, S.; Rambaux, N.; Ramos-Lerate, M.; Ranalli, P.; Rauw, G.; Read, A.; Regibo, S.; Renk, F.; Reylé, C.; Ribeiro, R. A.; Rimoldini, L.; Ripepi, V.; Riva, A.; Rixon, G.; Roelens, M.; Romero-Gómez, M.; Rowell, N.; Royer, F.; Rudolph, A.; Ruiz-Dern, L.; Sadowski, G.; Sagristà Sellés, T.; Sahlmann, J.; Salgado, J.; Salguero, E.; Sarasso, M.; Savietto, H.; Schnorhk, A.; Schultheis, M.; Sciacca, E.; Segol, M.; Segovia, J. C.; Segransan, D.; Serpell, E.; Shih, I. -C; Smareglia, R.; Smart, R. L.; Smith, C.; Solano, E.; Solitro, F.; Sordo, R.; Soria Nieto, S.; Souchay, J.; Spagna, A.; Spoto, F.; Stampa, U.; Steele, I. A.; Steidelmüller, H.; Stephenson, C. A.; Stoev, H.; Suess, F. F.; Süveges, M.; Surdej, J.; Szabados, L.; Szegedi-Elek, E.; Tapiador, D.; Taris, F.; Tauran, G.; Taylor, M. B.; Teixeira, R.; Terrett, D.; Tingley, B.; Trager, S. C.; Turon, C.; Ulla, A.; Utrilla, E.; Valentini, G.; van Elteren, A.; Van Hemelryck, E.; van Leeuwen, M.; Varadi, M.; Vecchiato, A.; Veljanoski, J.; Via, T.; Vicente, D.; Vogt, S.; Voss, H.; Votruba, V.; Voutsinas, S.; Walmsley, G.; Weiler, M.; Weingrill, K.; Werner, D.; Wevers, T.; Whitehead, G.; Wyrzykowski, Ł.; Yoldas, A.; Žerjal, M.; Zucker, S.; Zurbach, C.; Zwitter, T.; Alecu, A.; Allen, M.; Allende Prieto, C.; Amorim, A.; Anglada-Escudé, G.; Arsenijevic, V.; Azaz, S.; Balm, P.; Beck, M.; Bernstein, H. -H; Bigot, L.; Bijaoui, A.; Blasco, C.; Bonfigli, M.; Bono, G.; Boudreault, S.; Bressan, A.; Brown, S.; Brunet, P. -M; Bunclark, P.; Buonanno, R.; Butkevich, A. G.; Carret, C.; Carrion, C.; Chemin, L.; Chéreau, F.; Corcione, L.; Darmigny, E.; de Boer, K. S.; de Teodoro, P.; de Zeeuw, P. T.; Delle Luche, C.; Domingues, C. D.; Dubath, P.; Fodor, F.; Frézouls, B.; Fries, A.; Fustes, D.; Fyfe, D.; Gallardo, E.; Gallegos, J.; Gardiol, D.; Gebran, M.; Gomboc, A.; Gómez, A.; Grux, E.; Gueguen, A.; Heyrovsky, A.; Hoar, J.; Iannicola, G.; Isasi Parache, Y.; Janotto, A. -M; Joliet, E.; Jonckheere, A.; Keil, R.; Kim, D. -W; Klagyivik, P.; Klar, J.; Knude, J.; Kochukhov, O.; Kolka, I.; Kos, J.; Kutka, A.; Lainey, V.; LeBouquin, D.; Liu, C.; Loreggia, D.; Makarov, V. V.; Marseille, M. G.; Martayan, C.; Martinez-Rubi, O.; Massart, B.; Meynadier, F.; Mignot, S.; Munari, U.; Nguyen, A. -T; Nordlander, T.; Ocvirk, P.; O'Flaherty, K. S.; Olias Sanz, A.; Ortiz, P.; Osorio, J.; Oszkiewicz, D.; Ouzounis, A.; Palmer, M.; Park, P.; Pasquato, E.; Peltzer, C.; Peralta, J.; Péturaud, F.; Pieniluoma, T.; Pigozzi, E.; Poels, J.; Prat, G.; Prod'homme, T.; Raison, F.; Rebordao, J. M.; Risquez, D.; Rocca-Volmerange, B.; Rosen, S.; Ruiz-Fuertes, M. I.; Russo, F.; Sembay, S.; Serraller Vizcaino, I.; Short, A.; Siebert, A.; Silva, H.; Sinachopoulos, D.; Slezak, E.; Soffel, M.; Sosnowska, D.; Straižys, V.; ter Linden, M.; Terrell, D.; Theil, S.; Tiede, C.; Troisi, L.; Tsalmantza, P.; Tur, D.; Vaccari, M.; Vachier, F.; Valles, P.; Van Hamme, W.; Veltz, L.; Virtanen, J.; Wallut, J. -M; Wichmann, R.; Wilkinson, M. I.; Ziaeepour, H.; Zschocke, S.


    Gaia is a cornerstone mission in the science programme of the EuropeanSpace Agency (ESA). The spacecraft construction was approved in 2006, following a study in which the original interferometric concept was changed to a direct-imaging approach. Both the spacecraft and the payload were built by

  10. Mission from Mars

    DEFF Research Database (Denmark)

    Dindler, Christian; Eriksson, Eva; Iversen, Ole Sejer


    In this paper a particular design method is propagated as a supplement to existing descriptive approaches to current practice studies especially suitable for gathering requirements for the design of children's technology. The Mission from Mars method was applied during the design of an electronic...

  11. EOS Aura Mission Status (United States)

    Guit, William J.


    This PowerPoint presentation will discuss EOS Aura mission and spacecraft subsystem summary, recent and planned activities, inclination adjust maneuvers, propellant usage lifetime estimate. Eric Moyer, ESMO Deputy Project Manager-Technical (code 428) has reviewed and approved the slides on April 30, 2015.

  12. Robust UAV Mission Planning

    NARCIS (Netherlands)

    Evers, L.; Dollevoet, T; Barros, A.I.; Monsuur, H.


    Unmanned Aerial Vehicles (UAVs) can provide significant contributions to information gathering in military missions. UAVs can be used to capture both full motion video and still imagery of specific target locations within the area of interest. In order to improve the effectiveness of a

  13. Robust UAV Mission Planning

    NARCIS (Netherlands)

    L. Evers (Lanah); T.A.B. Dollevoet (Twan); A.I. Barros (Ana); H. Monsuur (Herman)


    textabstractUnmanned Areal Vehicles (UAVs) can provide significant contributions to information gathering in military missions. UAVs can be used to capture both full motion video and still imagery of specific target locations within the area of interest. In order to improve the effectiveness of a

  14. Robust UAV mission planning

    NARCIS (Netherlands)

    Evers, L.; Dollevoet, T.; Barros, A.I.; Monsuur, H.


    Unmanned Areal Vehicles (UAVs) can provide significant contributions to information gathering in military missions. UAVs can be used to capture both full motion video and still imagery of specific target locations within the area of interest. In order to improve the effectiveness of a reconnaissance

  15. Robust UAV Mission Planning

    NARCIS (Netherlands)

    Evers, L.; Dollevoet, T.; Barros, A.I.; Monsuur, H.


    Unmanned Aerial Vehicles (UAVs) can provide significant contributions to information gathering in military missions. UAVs can be used to capture both full motion video and still imagery of specific target locations within the area of interest. In order to improve the effectiveness of a

  16. The Lobster Mission (United States)

    Barthelmy, Scott


    I will give an overview of the Goddard Lobster mission: the science goals, the two instruments, the overall instruments designs, with particular attention to the wide-field x-ray instrument (WFI) using the lobster-eye-like micro-channel optics.

  17. Objective versus subjective assessment of laparoscopic skill

    NARCIS (Netherlands)

    van Empel, P.J.; van Rijssen, L.B.; Commandeur, J.P.; Verdam, M.G.E.; Huirne, J.A.; Scheele, F.; Bonjer, H.J.; Meijerink, W.J.


    Background: The equality of subjective- and objective-assessment methods in laparoscopic surgery are unknown. The aim of this study was to compare a subjective assessment method to an objective assessment method to evaluate laparoscopic skill. Methods: A prospective observational cohort study was

  18. The Unknown Computer Viruses Detection Based on Similarity (United States)

    Liu, Zhongda; Nakaya, Naoshi; Koui, Yuuji

    New computer viruses are continually being generated and they cause damage all over the world. In general, current anti-virus software detects viruses by matching a pattern based on the signature; thus, unknown viruses without any signature cannot be detected. Although there are some static analysis technologies that do not depend on signatures, virus writers often use code obfuscation techniques, which make it difficult to execute a code analysis. As is generally known, unknown viruses and known viruses share a common feature. In this paper we propose a new static analysis technology that can circumvent code obfuscation to extract the common feature and detect unknown viruses based on similarity. The results of evaluation experiments demonstrated that this technique is able to detect unknown viruses without false positives.

  19. Metastatic cervical carcinoma from an unknown primary: literature review

    National Research Council Canada - National Science Library

    Arrangoiz, Rodrigo; Galloway, Tom J; Papavasiliou, Pavlos; Ridge, John A; Lango, Miriam N


    Carcinoma of an unknown primary (CUP) encompasses a heterogeneous group of tumors for which no primary site can be detected following a thorough history, physical examination, and noninvasive and invasive testing...

  20. Using the Wheatstone Bridge to Compute Unknown Resistances. (United States)

    Schlenker, Richard M.

    This document presents a secondary level physics unit which introduces students to the Wheatstone Bridge, its use in determining the value of unknown resistors, and the effects of wiring resistors in series or in parallel. (SL)

  1. Bone metastases of unknown origin: epidemiology and principles of management

    National Research Council Canada - National Science Library

    Piccioli, Andrea; Maccauro, Giulio; Spinelli, Maria Silvia; Biagini, Roberto; Rossi, Barbara


    ... % of patients present with bone metastases of unknown origin, where the site of the primary neoplasm cannot be identified at the time of diagnosis despite a thorough history, physical examination...

  2. The Double Star mission

    Directory of Open Access Journals (Sweden)



    Full Text Available The Double Star Programme (DSP was first proposed by China in March, 1997 at the Fragrant Hill Workshop on Space Science, Beijing, organized by the Chinese Academy of Science. It is the first mission in collaboration between China and ESA. The mission is made of two spacecraft to investigate the magnetospheric global processes and their response to the interplanetary disturbances in conjunction with the Cluster mission. The first spacecraft, TC-1 (Tan Ce means "Explorer", was launched on 29 December 2003, and the second one, TC-2, on 25 July 2004 on board two Chinese Long March 2C rockets. TC-1 was injected in an equatorial orbit of 570x79000 km altitude with a 28° inclination and TC-2 in a polar orbit of 560x38000 km altitude. The orbits have been designed to complement the Cluster mission by maximizing the time when both Cluster and Double Star are in the same scientific regions. The two missions allow simultaneous observations of the Earth magnetosphere from six points in space. To facilitate the comparison of data, half of the Double Star payload is made of spare or duplicates of the Cluster instruments; the other half is made of Chinese instruments. The science operations are coordinated by the Chinese DSP Scientific Operations Centre (DSOC in Beijing and the European Payload Operations Service (EPOS at RAL, UK. The spacecraft and ground segment operations are performed by the DSP Operations and Management Centre (DOMC and DSOC in China, using three ground station, in Beijing, Shanghai and Villafranca.

  3. The Mothership Mission Architecture (United States)

    Ernst, S. M.; DiCorcia, J. D.; Bonin, G.; Gump, D.; Lewis, J. S.; Foulds, C.; Faber, D.


    The Mothership is considered to be a dedicated deep space carrier spacecraft. It is currently being developed by Deep Space Industries (DSI) as a mission concept that enables a broad participation in the scientific exploration of small bodies - the Mothership mission architecture. A Mothership shall deliver third-party nano-sats, experiments and instruments to Near Earth Asteroids (NEOs), comets or moons. The Mothership service includes delivery of nano-sats, communication to Earth and visuals of the asteroid surface and surrounding area. The Mothership is designed to carry about 10 nano-sats, based upon a variation of the Cubesat standard, with some flexibility on the specific geometry. The Deep Space Nano-Sat reference design is a 14.5 cm cube, which accommodates the same volume as a traditional 3U CubeSat. To reduce cost, Mothership is designed as a secondary payload aboard launches to GTO. DSI is offering slots for nano-sats to individual customers. This enables organizations with relatively low operating budgets to closely examine an asteroid with highly specialized sensors of their own choosing and carry out experiments in the proximity of or on the surface of an asteroid, while the nano-sats can be built or commissioned by a variety of smaller institutions, companies, or agencies. While the overall Mothership mission will have a financial volume somewhere between a European Space Agencies' (ESA) S- and M-class mission for instance, it can be funded through a number of small and individual funding sources and programs, hence avoiding the processes associated with traditional space exploration missions. DSI has been able to identify a significant interest in the planetary science and nano-satellite communities.

  4. The OCO-3 MIssion (United States)

    Eldering, A.; Kaki, S.; Crisp, D.; Gunson, M. R.


    For the OCO-3 mission, NASA has approved a proposal to install the OCO-2 flight spare instrument on the International Space Station (ISS). The OCO-3 mission on ISS will have a key role in delivering sustained, global, scientifically-based, spaceborne measurements of atmospheric CO2 to monitor natural sources and sinks as part of NASA's proposed OCO-2/OCO-3/ASCENDS mission sequence and NASA's Climate Architecture. The OCO-3 mission will contribute to understanding of the terrestrial carbon cycle through enabling flux estimates at smaller spatial scales and through fluorescence measurements that will reduce the uncertainty in terrestrial carbon flux measurements and drive bottom-up land surface models through constraining GPP. The combined nominal missions of both OCO-2 and OCO-3 will likely span a complete El Niño Southern Oscillation (ENSO) cycle, a key indicator of ocean variability. In addition, OCO-3 may allow investigation of the high-frequency and wavenumber structures suggested by eddying ocean circulation and ecosystem dynamics models. Finally, significant growth of urban agglomerations is underway and projected to continue in the coming decades. With the city mode sampling of the OCO-3 instrument on ISS we can evaluate different sampling strategies aimed at studying anthropogenic sources and demonstrate elements of a Greenhouse Gas Information system, as well as providing a gap-filler for tracking trends in the fastest-changing anthropogenic signals during the coming decade. In this presentation, we will describe our science objectives, the overall approach of utilization of the ISS for OCO-3, and the unique features of XCO2 measurements from ISS.

  5. Persistent Surveillance of Transient Events with Unknown Statistics (United States)


    stochastic and transient, their exact time of occurrence cannot be known apriori . Hence, the monitoring process requires the robot to visit each location and...unknown apriori . These relaxed assumptions are in contrast to previous problem definitions such as those in [1], [2], [3], where the statistics of...and the canonical problem of prediction with expert advice where the best expert is unknown apriori . An even more profound relationship and similarity

  6. Fast and Automatic Detection and Segmentation of Unknown Objects


    Kootstra, Gert; Bergström, Niklas; Kragic, Danica


    This paper focuses on the fast and automatic detection and segmentation of unknown objects in unknown environments. Many existing object detection and segmentation methods assume prior knowledge about the object or human interference. However, an autonomous system operating in the real world will often be confronted with previously unseen objects. To solve this problem, we propose a segmentation approach named Automatic Detection And Segmentation (ADAS). For the detection of objects, we use s...

  7. Stochastic Online Learning in Dynamic Networks under Unknown Models (United States)


    Stochastic Online Learning in Dynamic Networks under Unknown Models This research aims to develop fundamental theories and practical algorithms for...12211 Research Triangle Park, NC 27709-2211 Online learning , multi-armed bandit, dynamic networks REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S... Online Learning in Dynamic Networks under Unknown Models Report Title This research aims to develop fundamental theories and practical algorithms for

  8. Chinese Unknown Word Recognition for PCFG-LA Parsing

    Directory of Open Access Journals (Sweden)

    Qiuping Huang


    Full Text Available This paper investigates the recognition of unknown words in Chinese parsing. Two methods are proposed to handle this problem. One is the modification of a character-based model. We model the emission probability of an unknown word using the first and last characters in the word. It aims to reduce the POS tag ambiguities of unknown words to improve the parsing performance. In addition, a novel method, using graph-based semisupervised learning (SSL, is proposed to improve the syntax parsing of unknown words. Its goal is to discover additional lexical knowledge from a large amount of unlabeled data to help the syntax parsing. The method is mainly to propagate lexical emission probabilities to unknown words by building the similarity graphs over the words of labeled and unlabeled data. The derived distributions are incorporated into the parsing process. The proposed methods are effective in dealing with the unknown words to improve the parsing. Empirical results for Penn Chinese Treebank and TCT Treebank revealed its effectiveness.

  9. Lunar Precursor Missions for Human Exploration of Mars - II. Studies of Mission Operations (United States)

    Mendell, W. W.; Griffith, A. D.

    necessary precursor to human missions to Mars. He observed that mission parameters for Mars expeditions far exceed current and projected near-term space operations experience in categories such as duration, scale, logistics, required system reliability, time delay for communications, crew exposure to the space environment (particularly reduced gravity), lack of abort-to-Earth options, degree of crew isolation, and long-term political commitment. He demonstrated how a program of lunar exploration could be structured to expand the experience base, test operations approaches, and validate proposed technologies. In this paper, we plan to expand the discussion on the topic of mission operations, including flight and trajectory design, crew activity planning, procedure development and validation, and initialization load development. contemplating the nature of the challenges posed by a mission with a single crew lasting 3 years with no possibility of abort to Earth and at a distance where the light-time precludes conversation between with the astronauts. The brief durations of Apollo or Space Shuttle missions mandates strict scheduling of in-space tasks to maximize the productivity. On a mission to Mars, the opposite obtains. Transit times are long (~160 days), and crew time may be principally devoted to physical conditioning and repeated simulations of the landing sequence. While the physical exercise parallels the experience on the International Space Station (ISS), the remote refresher training is new. The extensive surface stay time (~500 days) implies that later phases of the surface missions will have to be planned in consultation with the crew to a large extent than is currently the case. resolve concerns over the form of new methodologies and philosophies needed. Recent proposed reductions in scope and crew size for ISS exacerbate this problem. One unknown aspect is whether any sociological pathologies will develop in the relationship of the crew to Mission

  10. NASA's Asteroid Redirect Mission (ARM) (United States)

    Abell, P. A.; Mazanek, D. D.; Reeves, D. M.; Chodas, P. W.; Gates, M. M.; Johnson, L. N.; Ticker, R. L.


    Mission Description and Objectives: NASA's Asteroid Redirect Mission (ARM) consists of two mission segments: 1) the Asteroid Redirect Robotic Mission (ARRM), a robotic mission to visit a large (greater than approximately 100 meters diameter) near-Earth asteroid (NEA), collect a multi-ton boulder from its surface along with regolith samples, and return the asteroidal material to a stable orbit around the Moon; and 2) the Asteroid Redirect Crewed Mission (ARCM), in which astronauts will explore and investigate the boulder and return to Earth with samples. The ARRM is currently planned to launch at the end of 2021 and the ARCM is scheduled for late 2026.

  11. B plant mission analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Lund, D.P.


    This report further develops the mission for B Plant originally defined in WHC-EP-0722, ``System Engineering Functions and Requirements for the Hanford Cleanup Mission: First Issue.`` The B Plant mission analysis will be the basis for a functional analysis that breaks down the B Plant mission statement into the necessary activities to accomplish the mission. These activities are the product of the functional analysis and will then be used in subsequent steps of the systems engineering process, such as identifying requirements and allocating those requirements to B Plant functions. The information in this mission analysis and the functional and requirements analysis are a part of the B Plant technical baseline.

  12. Nuclear Electric Propulsion mission operations. (United States)

    Prickett, W. Z.; Spera, R. J.


    Mission operations are presented for comet rendezvous and outer planet exploration missions conducted by unmanned Nuclear Electric Propulsion (NEP) system employing in-core thermionic reactors for electric power generation. The selected reference mission are Comet Halley rendezvous and a Jupiter orbiter at 5.9 planet radii, the orbit of the moon Io. Mission operations and options are defined from spacecraft assembly through mission completion. Pre-launch operations and related GSE requirements are identified. Shuttle launch and subsequent injection to earth escape by the Centaur d-1T are discussed, as well as power plant startup and heliocentric mission phases.

  13. Defining Space Mission Architects for the Smaller Missions (United States)

    Anderson, C.


    The definition of the Space Mission Architect (SMA) must be clear in both technical and human terms if we expect to train and/or to find people needed to architect the numbers of smaller missions expected in the future.

  14. 31 CFR 500.581 - Financial transactions related to diplomatic missions authorized. (United States)


    ... activities of North Korean diplomatic missions in the United States and U.S. diplomatic missions in North Korea are authorized, with the exception of transactions involving the North Korean mission to the United Nations in New York, which are subject to approval by specific license. ...

  15. Lynx mission concept study (United States)

    Vikhlinin, Alexey


    Lynx is an observatory-class mission, featuring high throughput, exquisite angular resolution over a substantial field of view, and high spectral resolution for point and extended X-ray sources. The design requirements provide a tremendous leap in capabilities relative to missions such as Chandra and Athena. Lynx will observe the dawn of supermassive black holes through detection of very faint X-ray sources in the early universe and will reveal the "invisible drivers" of galaxy and structure formation through observations of hot, diffuse baryons in and around the galaxies. Lynx will enable breakthroughs across all of astrophysics, ranging from detailed understanding of stellar activity including effects on habitability of associated planets to population statistics of neutron stars and black holes in the Local Group galaxies, to earliest groups and clusters of galaxies, and to cosmology

  16. The THEMIS Mission

    CERN Document Server

    Burch, J. L


    The THEMIS mission aims to determine the trigger and large-scale evolution of substorms by employing five identical micro-satellites which line up along the Earth's magnetotail to track the motion of particles, plasma, and waves from one point to another and for the first time, resolve space-time ambiguities in key regions of the magnetosphere on a global scale. The primary goal of THEMIS is to elucidate which magnetotail process is responsible for substorm onset at the region where substorm auroras map: (i) local disruption of the plasma sheet current (current disruption) or (ii) the interaction of the current sheet with the rapid influx of plasma emanating from reconnection. The probes also traverse the radiation belts and the dayside magnetosphere, allowing THEMIS to address additional baseline objectives. This volume describes the mission, the instrumentation, and the data derived from them.

  17. Towards A Shared Mission

    DEFF Research Database (Denmark)

    Staunstrup, Jørgen; Orth Gaarn-Larsen, Carsten

    in the context of universities. Although the economic aspects of value are important and cannot be ignored, we argue for a much richer interpretation of value that captures the many and varied results from universities. A shared mission is a prerequisite for university management and leadership. It makes......A mission shared by stakeholders, management and employees is a prerequisite for an engaging dialog about the many and substantial changes and challenges currently facing universities. Too often this essen-tial dialog reveals mistrust and misunderstandings about the role and outcome...... of the universities. The sad result is that the dialog about university development, resources, leadership, governance etc. too often ends up in rather fruitless discussions and sometimes even mutual suspicion. This paper argues for having a dialog involving both internal and external stakeholders agreeing...

  18. Precursor missions to interstellar exploration. (United States)

    Wallace, R. A.

    This paper summarizes material developed over a three-month period by a JPL team of mission architects/analysts and advanced technology developers for presentation to NASA Headquarters in the summer of 1998. A preliminary mission roadmap is suggested that leads to the exploration of star systems within 40 light years of our Solar System. The precursor missions include technology demonstrations as well as missions that return significant new knowledge about the space environment reached. Three propulsion technology candidates are selected on the basis of allowing eventual travel to the nearest star taking 10 years. One of the three propulsion technologies has a near term version applicable to early missions (prior to 2010) - the solar sail. Using early sail missions other critical supporting technologies can be developed that will later enable Interstellar travel. Example precursor missions are sail demonstration missions, including a solar storm warning mission demonstrating a simple sail, a solar polar imaging mission using an intermediate sail, and a 200-AU Heliosphere Explorer mission using an advanced solar sail. Mission and technology strategy, science return, and potential mission spin-offs are described.

  19. Joint Mission Command Implementation (United States)


    1 AIR WAR COLLEGE AIR UNIVERSITY JOINT MISSION COMMAND IMPLEMENTATION by Michael Dane Acord, COL, US Army A Research Report Submitted to...assigned to the Air War College, Air University, Maxwell Air Force Base (AFB), AL. Following the Army Command and General Staff College and School...holds a Bachelor’s Degree in Biology and two Masters Degrees, a Masters in Management from Troy University and a Master of Military Arts and Sciences

  20. The INTEGRAL mission

    DEFF Research Database (Denmark)

    Winkler, C.; Courvoisier, T.J.L.; Di Cocco, G.


    -angular resolution imaging (15 keV-10 MeV). Two monitors, JEM-X (Lund et al. 2003) in the (3-35) keV X-ray band, and OMC (Mas-Hesse et al. 2003) in optical Johnson V-band complement the payload. The ground segment includes the Mission Operations Centre at ESOC, ESA and NASA ground stations, the Science Operations...

  1. Space VLBI Mission: VSOP (United States)

    Murata, Yasuhiro; Hirabayashi, Hisashi; Kobayashi, Hideyuki; Shibata, Katsunori M.; Umemoto, Tomofumi; Edwards, P. G.


    We succeeded in performing space VLBI observations using the VLBI satellite HALCA (VSOP satellite), launched in February, 1997 aboard the first M-V rocket developed by ISAS. The mission is led by ISAS and NAO, with the collaborations from CRL, NASA, NRAO, and other institutes and observatories in Europe, Australia, Canada, South-Africa, and China, We succeeded to make a lot of observations and to get the new features from the active galaxies, the cosmic jets, and other astronomical objects.

  2. Mars Exploration Rover mission (United States)

    Crisp, Joy A.; Adler, Mark; Matijevic, Jacob R.; Squyres, Steven W.; Arvidson, Raymond E.; Kass, David M.


    In January 2004 the Mars Exploration Rover mission will land two rovers at two different landing sites that show possible evidence for past liquid-water activity. The spacecraft design is based on the Mars Pathfinder configuration for cruise and entry, descent, and landing. Each of the identical rovers is equipped with a science payload of two remote-sensing instruments that will view the surrounding terrain from the top of a mast, a robotic arm that can place three instruments and a rock abrasion tool on selected rock and soil samples, and several onboard magnets and calibration targets. Engineering sensors and components useful for science investigations include stereo navigation cameras, stereo hazard cameras in front and rear, wheel motors, wheel motor current and voltage, the wheels themselves for digging, gyros, accelerometers, and reference solar cell readings. Mission operations will allow commanding of the rover each Martian day, or sol, on the basis of the previous sol's data. Over a 90-sol mission lifetime, the rovers are expected to drive hundreds of meters while carrying out field geology investigations, exploration, and atmospheric characterization. The data products will be delivered to the Planetary Data System as integrated batch archives.

  3. Nanosatellite missions - the future (United States)

    Koudelka, O.; Kuschnig, R.; Wenger, M.; Romano, P.


    In the beginning, nanosatellite projects were focused on educational aspects. In the meantime, the technology matured and now allows to test, demonstrate and validate new systems, operational procedures and services in space at low cost and within much shorter timescales than traditional space endeavors. The number of spacecraft developed and launched has been increasing exponentially in the last years. The constellation of BRITE nanosatellites is demonstrating impressively that demanding scientific requirements can be met with small, low-cost satellites. Industry and space agencies are now embracing small satellite technology. Particularly in the USA, companies have been established to provide commercial services based on CubeSats. The approach is in general different from traditional space projects with their strict product/quality assurance and documentation requirements. The paper gives an overview of nanosatellite missions in different areas of application. Based on lessons learnt from the BRITE mission and recent developments at TU Graz (in particular the implementation of the OPS-SAT nanosatellite for ESA), enhanced technical possibilities for a future astronomy mission after BRITE will be discussed. Powerful on-board computers will allow on-board data pre-processing. A state-of-the-art telemetry system with high data rates would facilitate interference-free operations and increase science data return.

  4. The LISA Pathfinder Mission (United States)

    Thorpe, james; McNamara, P. W.


    LISA Pathfinder is a dedicated technology demonstration space mission for the Laser Interferometer Space Antenna (LISA), a NASA/ESA collaboration to operate a space-based observatory for gravitational waves in the milli-Hertz band. Although the formal partnership between the agencies was dissolved in the Spring of 2011, both agencies are actively pursuing concepts for LISA-like gravitational wave observatories. These concepts take advantage of the significant technology development efforts that have already been made, especially those of the LISA Pathfinder mission. LISA Pathfinder, which is in the late stages of implementation, will place two test masses in drag-free flight and measure the relative acceleration between them. This measurement will validate a number of technologies that are critical to LISA-like gravitational wave instruments including sensing and control of the test masses, drag-free control laws, microNewton thrusters, and picometer-level laser metrology. We will present the current status of the LISA Pathfinder mission and associated activities.

  5. Bion-11 Spaceflight Mission (United States)

    Skidmore, M.


    The Sensors 2000! Program, in support of the Space Life Sciences Payloads Office at NASA Ames Research Center developed a suite of bioinstrumentation hardware for use on the Joint US/Russian Bion I I Biosatellite Mission (December 24, 1996 - January 7, 1997). This spaceflight included 20 separate experiments that were organized into a complimentary and interrelated whole, and performed by teams of US, Russian, and French investigators. Over 40 separate parameters were recorded in-flight on both analog and digital recording media for later analysis. These parameters included; Electromyogram (7 ch), Electrogastrogram, Electrooculogram (2 ch), ECG/EKG, Electroencephlogram (2 ch), single fiber firing of Neurovestibular afferent nerves (7 ch), Tendon Force, Head Motion Velocity (pitch & yaw), P02 (in vivo & ambient), temperature (deep body, skin, & ambient), and multiple animal and spacecraft performance parameters for a total of 45 channels of recorded data. Building on the close cooperation of previous missions, US and Russian engineers jointly developed, integrated, and tested the physiologic instrumentation and data recording system. For the first time US developed hardware replaced elements of the Russian systems resulting in a US/Russian hybrid instrumentation and data system that functioned flawlessly during the 14 day mission.

  6. Landsat Data Continuity Mission (United States)



    The Landsat Data Continuity Mission (LDCM) is a partnership formed between the National Aeronautics and Space Administration (NASA) and the U.S. Geological Survey (USGS) to place the next Landsat satellite in orbit in January 2013. The Landsat era that began in 1972 will become a nearly 41-year global land record with the successful launch and operation of the LDCM. The LDCM will continue the acquisition, archiving, and distribution of multispectral imagery affording global, synoptic, and repetitive coverage of the Earth's land surfaces at a scale where natural and human-induced changes can be detected, differentiated, characterized, and monitored over time. The mission objectives of the LDCM are to (1) collect and archive medium resolution (30-meter spatial resolution) multispectral image data affording seasonal coverage of the global landmasses for a period of no less than 5 years; (2) ensure that LDCM data are sufficiently consistent with data from the earlier Landsat missions in terms of acquisition geometry, calibration, coverage characteristics, spectral characteristics, output product quality, and data availability to permit studies of landcover and land-use change over time; and (3) distribute LDCM data products to the general public on a nondiscriminatory basis at no cost to the user.

  7. Multi-Mission SDR Project (United States)

    National Aeronautics and Space Administration — Wireless transceivers used for NASA space missions have traditionally been highly custom and mission specific. Programs such as the GRC Space Transceiver Radio...

  8. Mission Critical Occupation (MCO) Charts (United States)

    Office of Personnel Management — Agencies report resource data and targets for government-wide mission critical occupations and agency specific mission critical and/or high risk occupations. These...

  9. Exomars Mission Achievements (United States)

    Lecomte, J.; Juillet, J. J.


    ExoMars is the first step of the European Space Agency's Aurora Exploration Programme. Comprising two missions, the first one launched in 2016 and the second one to be launched in 2020, ExoMars is a program developed in a broad ESA and Roscosmos co-operation, with significant contribution from NASA that addresses the scientific question of whether life ever existed on Mars and demonstrate key technologies for entry, descent, landing, drilling and roving on the Martian surface . Thales Alenia Space is the overall prime contractor of the Exomars program leading a large industrial team The Spacecraft Composite (SCC), consisting of a Trace Gas Orbiter (TGO) and an EDL (Entry Descend and Landing) Demonstrator Module (EDM) named Schiaparelli, has been launched on 14 March 2016 from the Baikonur Cosmodrome by a Proton Launcher. The two modules will separate on 16 October 2016 after a 7 months cruise. The TGO will search for evidence of methane and other atmospheric gases that could be signatures of active biological or geological processes on Mars and will provide communications relay for the 2020 surface assets. The Schiaparelli module will prove the technologies required to safely land a payload on the surface of Mars, with a package of sensors aimed to support the reconstruction of the flown trajectory and the assessment of the performance of the EDL subsystems. For the second Exomars mission a space vehicle composed of a Carrier Module (CM) and a Descent Module (DM), whose Landing Platform (LP) will house a Rover, will begin a 7 months long trip to Mars in August 2020. In 2021 the Descent Module will be separated from the Carrier to carry out the entry into the planet's atmosphere and subsequently make the Landing Platform and the Rover land gently on the surface of Mars. While the LP will continue to measure the environmental parameters of the landing site, the Rover will begin exploration of the surface, which is expected to last 218 Martian days (approx. 230 Earth

  10. Biomarkers for Ectopic Pregnancy and Pregnancy of Unknown Location (United States)

    Senapati, Suneeta; Barnhart, Kurt T.


    Early pregnancy failure is the most common complication of pregnancy, and 1–2% of all pregnancies will be ectopic. As one of the leading causes of maternal morbidity and mortality, diagnosing ectopic pregnancy and determining the fate of a pregnancy of unknown location are of great clinical concern. Several serum and plasma biomarkers for ectopic pregnancy have been investigated independently and in combination. The following is a review of the state of biomarker discovery and development for ectopic pregnancy and pregnancy of unknown location. PMID:23290746

  11. Fever of unknown origin, giant cell arteritis, and aortic dissection. (United States)

    Hofheinz, K; Bertz, S; Wacker, J; Schett, G; Manger, B


    Giant cell arteritis is one of the most frequent causes of pyrexia of unknown origin after infectious or malignant causes have been ruled out. In this case report we describe a 66-year old female patient, who after five weeks of remitting fever developed a life-threatening, painless severe aortic dissection. The timely use of modern imaging technologies such as magnetic resonance angiography or positron emission computed tomography could in the future be of help to recognize aortic involvement early and to avoid this devastating complication in patients with fever of unknown origin.

  12. Prediction of Primary Tumors in Cancers of Unknown Primary

    DEFF Research Database (Denmark)

    Søndergaard, Dan; Nielsen, Svend; Pedersen, Christian N S


    A cancer of unknown primary (CUP) is a metastatic cancer for which standard diagnostic tests fail to identify the location of the primary tumor. CUPs account for 3-5% of cancer cases. Using molecular data to determine the location of the primary tumor in such cases can help doctors make the right...... treatment choice and thus improve the clinical outcome. In this paper, we present a new method for predicting the location of the primary tumor using gene expression data: locating cancers of unknown primary (LoCUP). The method models the data as a mixture of normal and tumor cells and thus allows correct...

  13. TDEM for Martian in situ resource prospecting missions

    Directory of Open Access Journals (Sweden)

    G. Tacconi


    Full Text Available This paper presents a TDEM (Time Domain Electromagnetic Methods application, addressed to the search for water on Mars. In this context, the opportunities for a TDEM system as payload in a future mission are investigated for different in situ exploration scenarios. The TDEM sounding capability is evaluated with respect to the expected Martian environment, and some considerations are made about the many unknown variables (above all the background EM noise and the subsoil composition altogether with the limited resources availability (mission constraints in mass, time and power and the way they could represent an obstacle for operations and measurements.

  14. Extensive screening for primary tumor is redundant in melanoma of unknown primary

    DEFF Research Database (Denmark)

    Tos, Tina; Klyver, Helle; Drzewiecki, Krzysztof T


    primary tumor during the period 1986-2006, 39 (38%) presented primarily with a cutaneous or a subcutaneous metastasis, and 63 (61%) with a lymph node metastasis. One patient presented with a bone metastasis (1%). Eighty-seven patients (84%) were examined by an ophthalmologist. A choroidal melanoma......For decades, patients in our institution with metastastic melanoma of unknown primary have been subjected to extensive examinations in search of the primary tumor. This retrospective study questions the results, and thus the feasibility of these examinations. Of 103 patients diagnosed with unknown...... (89%), revealing no primary tumor. We conclude, that only one possible (but not verified) primary tumor was disclosed by various specialists examinations of 103 patients referred with the diagnosis metastatic melanoma with no primary tumor. Special screenings can thus be considered as redundant. Thus...

  15. Adaptive fuzzy prescribed performance control for MIMO nonlinear systems with unknown control direction and unknown dead-zone inputs. (United States)

    Shi, Wuxi; Luo, Rui; Li, Baoquan


    In this study, an adaptive fuzzy prescribed performance control approach is developed for a class of uncertain multi-input and multi-output (MIMO) nonlinear systems with unknown control direction and unknown dead-zone inputs. The properties of symmetric matrix are exploited to design adaptive fuzzy prescribed performance controller, and a Nussbaum-type function is incorporated in the controller to estimate the unknown control direction. This method has two prominent advantages: it does not require the priori knowledge of control direction and only three parameters need to be updated on-line for this MIMO systems. It is proved that all the signals in the resulting closed-loop system are bounded and that the tracking errors converge to a small residual set with the prescribed performance bounds. The effectiveness of the proposed approach is validated by simulation results. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  16. Climate Benchmark Missions: CLARREO (United States)

    Wielicki, Bruce A.; Young, David F.


    CLARREO (Climate Absolute Radiance and Refractivity Observatory) is one of the four Tier 1 missions recommended by the recent NRC decadal survey report on Earth Science and Applications from Space (NRC, 2007). The CLARREO mission addresses the need to rigorously observe climate change on decade time scales and to use decadal change observations as the most critical method to determine the accuracy of climate change projections such as those used in the Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC AR4). A rigorously known accuracy of both decadal change observations as well as climate projections is critical in order to enable sound policy decisions. The CLARREO mission accomplishes this critical objective through highly accurate and SI traceable decadal change observations sensitive to many of the key uncertainties in climate radiative forcings, responses, and feedbacks that in turn drive uncertainty in current climate model projections. The same uncertainties also lead to uncertainty in attribution of climate change to anthropogenic forcing. The CLARREO breakthrough in decadal climate change observations is to achieve the required levels of accuracy and traceability to SI standards for a set of observations sensitive to a wide range of key decadal change variables. These accuracy levels are determined both by the projected decadal changes as well as by the background natural variability that such signals must be detected against. The accuracy for decadal change traceability to SI standards includes uncertainties of calibration, sampling, and analysis methods. Unlike most other missions, all of the CLARREO requirements are judged not by instantaneous accuracy, but instead by accuracy in large time/space scale average decadal changes. Given the focus on decadal climate change, the NRC Decadal Survey concluded that the single most critical issue for decadal change observations was their lack of accuracy and low confidence in

  17. Enabling the human mission (United States)

    Bosley, John

    The duplication of earth conditions aboard a spacecraft or planetary surface habitat requires 60 lb/day/person of food, potable and hygiene water, and oxygen. A 1000-day mission to Mars would therefore require 30 tons of such supplies per crew member in the absence of a closed-cycle, or regenerative, life-support system. An account is given of the development status of regenerative life-support systems, as well as of the requisite radiation protection and EVA systems, the health-maintenance and medical care facilities, zero-gravity deconditioning measures, and planetary surface conditions protection.

  18. SOFIA mission operations (United States)

    Waddell, Patrick G.; Davidson, Jacqueline A.


    The SOFIA Airborne Observatory will operate a 2.5 m aperture telescope with the goal of obtaining over 960 successful science hours per year at a nominal altitude of 12.5 km and covering a wavelength range from 0.3 mm to 1.6 mm. The observatory platform is comprised of a Boeing 747SP with numerous significant modifications. The ground and flight mission operations architectures and plans are tailored to keep the telescope emissivity low and achieve high observing efficiency.

  19. The ARTEMIS mission

    CERN Document Server

    Angelopoulos, Vassilis


    The ARTEMIS mission was initiated by skillfully moving the two outermost Earth-orbiting THEMIS spacecraft into lunar orbit to conduct unprecedented dual spacecraft observations of the lunar environment. ARTEMIS stands for Acceleration, Reconnection, Turbulence and Electrodynamics of the Moon's Interaction with the Sun. Indeed, this volume discusses initial findings related to the Moon’s magnetic and plasma environments and the electrical conductivity of the lunar interior. This work is aimed at researchers and graduate students in both heliophysics and planetary physics. Originally published in Space Science Reviews, Vol. 165/1-4, 2011.

  20. Detection of unknown occult primary tumors using positron emission tomography

    NARCIS (Netherlands)

    Kole, AC; Nieweg, OE; Pruim, J; Hoekstra, HJ; Roodenburg, JLN; Vaalburg, W; Vermey, A; Schraffordt Koops, H.


    BACKGROUND. The potential of positron emission tomography (PET) with F-18-fluoro-2-deoxy-D-glucose (FDG) to detect primary tumors after unsuccessful conventional diagnostic workup was assessed in patients with metastatic disease from an unknown primary tumor. METHODS. Twenty-nine patients with

  1. Prevalence and predictors of unknown HIV status among women ...

    African Journals Online (AJOL)

    Introduction: Knowledge of a person's HIV status during pregnancy is critical for prevention of mother to child transmission of HIV. Objectives: To determine the prevalence and factors associated with unknown HIV status among women delivering in Mulago Hospital. Methods: This was a cross-sectional study of women that ...

  2. Severe scratcher-reaction: an unknown health hazard?

    Directory of Open Access Journals (Sweden)

    Carsten Sauer Mikkelsen


    Full Text Available Tattoos are well known to cause skin problems and the number of reported adverse reactions after tattooing has increased. Illegally imported tattoo ink is unrestrained and can contain unknown ingredients and contamination thereby posing a serious health hazard. We present a case illustrating the risk of pronounced phototoxic allergic reaction and other severe complications after using home kit tattoo ink.

  3. RBF neural network based H∞ synchronization for unknown chaotic ...

    Indian Academy of Sciences (India)

    MS received 9 February 2010; accepted 24 May 2010. Abstract. In this paper, we propose a new H∞ synchronization strategy, called a. Radial Basis Function Neural Network H∞ synchronization (RBFNNHS) strategy, for unknown chaotic systems in the presence of external disturbance. In the pro- posed framework, a ...

  4. Bayesian Compressed Sensing with Unknown Measurement Noise Level

    DEFF Research Database (Denmark)

    Hansen, Thomas Lundgaard; Jørgensen, Peter Bjørn; Pedersen, Niels Lovmand


    In sparse Bayesian learning (SBL) approximate Bayesian inference is applied to find sparse estimates from observations corrupted by additive noise. Current literature only vaguely considers the case where the noise level is unknown a priori. We show that for most state-of-the-art reconstruction...

  5. Inventory control in case of unknown demand and control parameters

    NARCIS (Netherlands)

    Janssen, E.


    This thesis deals with unknown demand and control parameters in inventory control. Inventory control involves decisions on what to order when and in what quantity. These decisions are based on information about the demand. Models are constructed using complete demand information; these models ensure

  6. Designing towards the Unknown: Engaging with Material and Aesthetic Uncertainty

    Directory of Open Access Journals (Sweden)

    Danielle Wilde


    Full Text Available New materials with new capabilities demand new ways of approaching design. Destabilising existing methods is crucial to develop new methods. Yet, radical destabilisation—where outcomes remain unknown long enough that new discoveries become possible—is not easy in technology design where complex interdisciplinary teams with time and resource constraints need to deliver concrete outcomes on schedule. The Poetic Kinaesthetic Interface project (PKI engages with this problematic directly. In PKI we use unfolding processes—informed by participatory, speculative and critical design—in emergent actions, to design towards unknown outcomes, using unknown materials. The impossibility of this task is proving as useful as it is disruptive. At its most potent, it is destabilising expectations, aesthetics and processes. Keeping the researchers, collaborators and participants in a state of unknowing, is opening the research potential to far-ranging possibilities. In this article we unpack the motivations driving the PKI project. We present our mixed-methodology, which entangles textile crafts, design interactions and materiality to shape an embodied enquiry. Our research outcomes are procedural and methodological. PKI brings together diverse human, non-human, known and unknown actors to discover where the emergent assemblages might lead. Our approach is re-invigorating—as it demands re-envisioning of—the design process.

  7. A Size Exclusion Chromatography Laboratory with Unknowns for Introductory Students (United States)

    McIntee, Edward J.; Graham, Kate J.; Colosky, Edward C.; Jakubowski, Henry V.


    Size exclusion chromatography is an important technique in the separation of biological and polymeric samples by molecular weight. While a number of laboratory experiments have been published that use this technique for the purification of large molecules, this is the first report of an experiment that focuses on purifying an unknown small…

  8. Editoria: EBOLA: Fear of the unknown | Comoro | Tanzania Journal ...

    African Journals Online (AJOL)

    Tanzania Journal of Health Research. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 3, No 2 (2001) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Editoria: EBOLA: Fear of the unknown. C. Comoro, J.

  9. Prevalence and predictors of unknown HIV status among women ...

    African Journals Online (AJOL)

    The labour ward on 5C admits high risk women and re- ferrals from the formal and informal health sector. There are about 2300 deliveries at ward 5C per month. The HIV status of every woman is identified at admission, those with unknown HIV status receive HCT and if positive, are given emergency ARVs for PMTCT.

  10. Anal Cancer debuting as Cancer of Unknown Primary

    DEFF Research Database (Denmark)

    Sveistrup, Joen; Loft, Annika; Engelholm, Svend Aage


    Anal cancer usually presents with a visible or palpable tumour. In this case we describe a 54-year old man diagnosed with Cancer of Unknown Primary (CUP) with a single inguinal node as the only finding. Thorough examination failed to identify any primary tumour. The patient was treated with lymph...

  11. Energy data base: subject thesaurus

    Energy Technology Data Exchange (ETDEWEB)

    Redford, J.S. (ed.)


    The technical staff of the DOE Technical Information Center, during its subject indexing activities, develops and structures a vocabulary that allows consistent machine storage and retrieval of information necessary to the accomplishment of the DOE mission. This thesaurus incorporates that structured vocabulary. The terminology of this thesaurus is used for the subject control of information announced in DOE Energy Research Abstracts, Energy Abstracts for Policy Analysis, and various update journals and bulletins in specialized areas. This terminology also facilitates subject searching of the DOE Energy Data Base on the DOE/RECON on-line retrieval system and on other commercial retrieval systems. The rapid expansion of the DOE's activities will result in a commitant thesaurus expansion as information relating to new activities is indexed. Only the terms used in the indexing of documents at the Technical Information Center to date are included. (JSR)

  12. Intelligent behaviors for a convoy of indoor mobile robots operating in unknown environments (United States)

    Farrington, Nathan M.; Nguyen, Hoa G.; Pezeshkian, Narek


    Intelligent behaviors allow a convoy of small indoor robots to perform high-level mission tasking. These behaviors include various implementations of map building, localization, obstacle avoidance, object recognition, and navigation. Several behaviors have been developed by SSC San Diego, with integration of other behaviors developed by open-source projects and a technology transfer effort funded by DARPA. The test system, developed by SSC San Diego, consists of ROBART III (a prototype security robot), serving as the master platform, and a convoy of four ActivMedia Pioneer 2-DX robots. Each robot, including ROBART III, is equipped with a SICK LMS 200 laser rangefinder. Using integrated wireless network repeaters, the Pioneer 2-DX robots maintain an ad hoc communication link between the operator and ROBART III. The Pioneer 2-DX robots can also act as rear guards to detect intruders in areas that ROBART III has previously explored. These intelligent behaviors allow a single operator to command the entire convoy of robots during a mission in an unknown environment.

  13. Bayesian source term determination with unknown covariance of measurements (United States)

    Belal, Alkomiet; Tichý, Ondřej; Šmídl, Václav


    Determination of a source term of release of a hazardous material into the atmosphere is a very important task for emergency response. We are concerned with the problem of estimation of the source term in the conventional linear inverse problem, y = Mx, where the relationship between the vector of observations y is described using the source-receptor-sensitivity (SRS) matrix M and the unknown source term x. Since the system is typically ill-conditioned, the problem is recast as an optimization problem minR,B(y - Mx)TR-1(y - Mx) + xTB-1x. The first term minimizes the error of the measurements with covariance matrix R, and the second term is a regularization of the source term. There are different types of regularization arising for different choices of matrices R and B, for example, Tikhonov regularization assumes covariance matrix B as the identity matrix multiplied by scalar parameter. In this contribution, we adopt a Bayesian approach to make inference on the unknown source term x as well as unknown R and B. We assume prior on x to be a Gaussian with zero mean and unknown diagonal covariance matrix B. The covariance matrix of the likelihood R is also unknown. We consider two potential choices of the structure of the matrix R. First is the diagonal matrix and the second is a locally correlated structure using information on topology of the measuring network. Since the inference of the model is intractable, iterative variational Bayes algorithm is used for simultaneous estimation of all model parameters. The practical usefulness of our contribution is demonstrated on an application of the resulting algorithm to real data from the European Tracer Experiment (ETEX). This research is supported by EEA/Norwegian Financial Mechanism under project MSMT-28477/2014 Source-Term Determination of Radionuclide Releases by Inverse Atmospheric Dispersion Modelling (STRADI).

  14. Gospel, culture and mission: Revisiting an enduring problem

    Directory of Open Access Journals (Sweden)

    O.U. Kalu


    Full Text Available Gospel, culture and mission: Revisiting an enduring problem This article reflects on the 1996 Conference on World Mission and Evangelism. The relation between gospel, culture and mission is considered, especially from an Africa perspective, but not reserved to it in application. Apart from considering the problem of appropriate terminology to express the intricacies concerning the subject, a deeper search is conducted into the complex relationship between the believer, his mission to, and his distancing from divergent cultural sources and manifestations. Emerging perspectives are considered, which help to formulate mission strategies and historic viewpoints and attitudes. Knowledge of these perspectives is essential for a more responsible answering to the call made to all believers.

  15. Self-calibration rank filter for unknown dynamic inputs mitigation during the Mars powered descent phase (United States)

    Xiao, Qiang; Fu, Huimin; Deng, Zhibao; Bai, Huanxu; Wang, Sheng; Sun, Mingyi


    Advanced navigation systems for pinpoint landing are required in the entry, descent and landing phase of future missions to Mars. To overcome the horizontal position estimation problem in the Mars powered descent phase, the inertial measurement unit, Doppler radar and surface beacon integrated navigation scheme is proposed, and a conventional filter such as an extended or unscented Kalman filter is adopted. However, in engineering practice, these conventional filters for nonlinear systems with unknown dynamic inputs may degrade or even diverge. The lack of navigation accuracy may result in a large growth of spurious navigations. To solve this problem, based on the rank filter, a self-calibration rank filter is proposed for state estimation of a nonlinear system to mitigate the effects of unknown dynamic inputs. Monte Carlo simulation results are presented to demonstrate the good performance of the self-calibration rank filter for the Mars powered descent navigation. The self-calibration rank filter not only prevents the divergence of the filtering but also significantly improves the state estimation accuracy.

  16. EU Universities’ Mission Statements

    Directory of Open Access Journals (Sweden)

    Liudmila Arcimaviciene


    Full Text Available In the last 10 years, a highly productive space of metaphor analysis has been established in the discourse studies of media, politics, business, and education. In the theoretical framework of Conceptual Metaphor Theory and Critical Discourse Analysis, the restored metaphorical patterns are especially valued for their implied ideological value as realized both conceptually and linguistically. By using the analytical framework of Critical Metaphor Analysis and procedurally employing Pragglejaz Group’s Metaphor Identification Procedure, this study aims at analyzing the implied value of the evoked metaphors in the mission statements of the first 20 European Universities, according to the Webometrics ranking. In this article, it is proposed that Universities’ mission statements are based on the positive evaluation of the COMMERCE metaphor, which does not fully correlate with the ideological framework of sustainability education but is rather oriented toward consumerism in both education and society. Despite this overall trend, there are some traceable features of the conceptualization reflecting the sustainability approach to higher education, as related to freedom of speech, tolerance, and environmental concerns. Nonetheless, these are suppressed by the metaphoric usages evoking traditional dogmas of the conservative ideology grounded in the concepts of the transactional approach to relationship, competitiveness for superiority, the importance of self-interest and strength, and quantifiable quality.

  17. Apollo 11 Mission Commemorated (United States)

    Showstack, Randy


    On 24 July 1969, 4 days after Apollo 11 Mission Commander Neil Armstrong and Lunar Module Eagle Pilot Eugene “Buzz” Aldrin had become the first people to walk on the Moon, they and Apollo 11 Command Module Pilot Michael Collins peered through a window of the Mobile Quarantine Facility on board the U.S.S. Hornet following splashdown of the command module in the central Pacific as U.S. President Richard Nixon told them, “This is the greatest week in the history of the world since the creation.” Forty years later, the Apollo 11 crew and other Apollo-era astronauts gathered at several events in Washington, D. C., to commemorate and reflect on the Apollo program, that mission, and the future of manned spaceflight. “I don’t know what the greatest week in history is,” Aldrin told Eos. “But it was certainly a pioneering opening the door. With the door open when we touched down on the Moon, that was what enabled humans to put many more footprints on the surface of the Moon.”

  18. The Global Precipitation Mission (United States)

    Braun, Scott; Kummerow, Christian


    The Global Precipitation Mission (GPM), expected to begin around 2006, is a follow-up to the Tropical Rainfall Measuring Mission (TRMM). Unlike TRMM, which primarily samples the tropics, GPM will sample both the tropics and mid-latitudes. The primary, or core, satellite will be a single, enhanced TRMM satellite that can quantify the 3-D spatial distributions of precipitation and its associated latent heat release. The core satellite will be complemented by a constellation of very small and inexpensive drones with passive microwave instruments that will sample the rainfall with sufficient frequency to be not only of climate interest, but also have local, short-term impacts by providing global rainfall coverage at approx. 3 h intervals. The data is expected to have substantial impact upon quantitative precipitation estimation/forecasting and data assimilation into global and mesoscale numerical models. Based upon previous studies of rainfall data assimilation, GPM is expected to lead to significant improvements in forecasts of extratropical and tropical cyclones. For example, GPM rainfall data can provide improved initialization of frontal systems over the Pacific and Atlantic Oceans. The purpose of this talk is to provide information about GPM to the USWRP (U.S. Weather Research Program) community and to discuss impacts on quantitative precipitation estimation/forecasting and data assimilation.

  19. Cyberspace Warfare: A New DoD Core Mission Area (United States)


    directive from being implemented. May 2014: U.S. oil companies report unknown hackers gained unauthorized access to some of their offshore platforms ...measures to secure their gaming environment from these exploits by hiring security experts who could find, fix , and mitigate them. If not, the clearly something that could ensure mission success. The core goal is to “disrupt, dismantle , and defeat Al-Qaeda and prevent Afghanistan from

  20. General Mission Analysis Tool (GMAT): Mission, Vision, and Business Case (United States)

    Hughes, Steven P.


    The Goal of the GMAT project is to develop new space trajectory optimization and mission design technology by working inclusively with ordinary people, universities businesses and other government organizations; and to share that technology in an open and unhindered way. GMAT's a free and open source software system; free for anyone to use in development of new mission concepts or to improve current missions, freely available in source code form for enhancement or future technology development.

  1. Into the Unknown Together. The DOD, NASA, and Early Spaceflight (United States)


    aircraft, all technologically obsolete, when compared to France with 1,400, Germany with 1,000, Russia with 800, and England with 400.74 In the wartime...reentry materials were perfected) and into NASA’s later Mercury, Gemini, and Apollo space capsules . After World War II, the NACA did enough research...the bibliography.) 1. Apollo hardware and its Saturn family of launch vehicles were also used for the three Skylab missions in 1973 and the Apollo Soyuz

  2. The science planning process on the Rosetta mission (United States)

    Vallat, Claire; Altobelli, Nicolas; Geiger, Bernhard; Grieger, Bjoern; Kueppers, Michael; Muñoz Crego, Claudio; Moissl, Richard; Taylor, Matthew G. G. T.; Alexander, Claudia; Buratti, Bonnie; Choukroun, Mathieu; the RSGS Liaison scientists group


    The Rosetta mission arrived at comet 67 P/Churyumov-Gerasimenko in Summer 2014, after more than 10 years in space. All previous mission encounters with a comet have provided a snapshot of the cometary activity at a given heliocentric distance. In contrast, Rosetta has escorted the comet nucleus for an extended period (>2 years) at a large range of cometo-centric and heliocentric distances, which has provided exceptional and unprecedented observing conditions to study, analyse and monitor 67 P during its passage to, through and away from perihelion. One of the biggest challenges of this mission is the development of an observation plan that adequately addresses the mission's science objectives while coping with a largely unknown and continuously evolving environment that constantly modifies the planning constraints. The Rosetta Science Ground Segment (RSGS), in support of the Project Scientist and the Science Working Team, is in charge of translating the high level mission science objectives into a low level pointing and operations plan. We present here the high-level science planning process adopted during the comet escort phase. We describe the main science objectives addressed along the mission lifetime, the different groups involved in the science planning, and the approach followed to translate those requirements into a viable and scientifically valid operations plan. Finally, we describe how the science planning scheme has evolved since arrival at the comet to react to the unexpected environment, largely reducing the planning lead times.

  3. Quadrotor Control in the Presence of Unknown Mass Properties (United States)

    Duivenvoorden, Rikky Ricardo Petrus Rufino

    Quadrotor UAVs are popular due to their mechanical simplicity, as well as their capability to hover and vertically take-off and land. As applications diversify, quadrotors are increasingly required to operate under unknown mass properties, for example as a multirole sensor platform or for package delivery operations. The work presented here consists of the derivation of a generalized quadrotor dynamic model without the typical simplifying assumptions on the first and second moments of mass. The maximum payload capacity of a quadrotor in hover, and the observability of the unknown mass properties are discussed. A brief introduction of L1 adaptive control is provided, and three different L 1 adaptive controllers were designed for the Parrot AR.Drone quadrotor. Their tracking and disturbance rejection performance was compared to the baseline nonlinear controller in experiments. Finally, the results of the combination of L1 adaptive control with iterative learning control are presented, showing high performance trajectory tracking under uncertainty.

  4. Towards high-speed autonomous navigation of unknown environments (United States)

    Richter, Charles; Roy, Nicholas


    In this paper, we summarize recent research enabling high-speed navigation in unknown environments for dynamic robots that perceive the world through onboard sensors. Many existing solutions to this problem guarantee safety by making the conservative assumption that any unknown portion of the map may contain an obstacle, and therefore constrain planned motions to lie entirely within known free space. In this work, we observe that safety constraints may significantly limit performance and that faster navigation is possible if the planner reasons about collision with unobserved obstacles probabilistically. Our overall approach is to use machine learning to approximate the expected costs of collision using the current state of the map and the planned trajectory. Our contribution is to demonstrate fast but safe planning using a learned function to predict future collision probabilities.

  5. Learning Unknown Structure in CRFs via Adaptive Gradient Projection Method

    Directory of Open Access Journals (Sweden)

    Wei Xue


    Full Text Available We study the problem of fitting probabilistic graphical models to the given data when the structure is not known. More specifically, we focus on learning unknown structure in conditional random fields, especially learning both the structure and parameters of a conditional random field model simultaneously. To do this, we first formulate the learning problem as a convex minimization problem by adding an l_2-regularization to the node parameters and a group l_1-regularization to the edge parameters, and then a gradient-based projection method is proposed to solve it which combines an adaptive stepsize selection strategy with a nonmonotone line search. Extensive simulation experiments are presented to show the performance of our approach in solving unknown structure learning problems.

  6. Renal disease masquerading as pyrexia of unknown origin

    Directory of Open Access Journals (Sweden)

    D Korivi


    Full Text Available Pyrexia of unknown origin is a challenging clinical problem. Infections, malignancies, and connective tissue diseases form the major etiologies for this condition. We report a case of a 57-year-old diabetic male who presented with fever of unknown origin for several months. The course of investigations led to a kidney biopsy which clinched the cause of his fever as well as the underlying diagnosis. The light microscopy findings of expansile storiform fibrosis with a dense inflammatory infiltrate suggested the diagnosis which was confirmed by positive staining of Immunoglobulin G4, the dense lympho-plasmacytic infiltrate and elevated serum IgG4 concentrations. A course of steroids followed by mycophenolate mofetil as maintenance immunosuppression rendered the patient afebrile with improvement of renal function.

  7. Venus Aerobot Multisonde Mission (United States)

    Cutts, James A.; Kerzhanovich, Viktor; Balaram, J. Bob; Campbell, Bruce; Gershaman, Robert; Greeley, Ronald; Hall, Jeffery L.; Cameron, Jonathan; Klaasen, Kenneth; Hansen, David M.


    Robotic exploration of Venus presents many challenges because of the thick atmosphere and the high surface temperatures. The Venus Aerobot Multisonde mission concept addresses these challenges by using a robotic balloon or aerobot to deploy a number of short lifetime probes or sondes to acquire images of the surface. A Venus aerobot is not only a good platform for precision deployment of sondes but is very effective at recovering high rate data. This paper describes the Venus Aerobot Multisonde concept and discusses a proposal to NASA's Discovery program using the concept for a Venus Exploration of Volcanoes and Atmosphere (VEVA). The status of the balloon deployment and inflation, balloon envelope, communications, thermal control and sonde deployment technologies are also reviewed.

  8. Evaluation of Unknown Tube Well Depth Using Electrical Resistivity Method

    Directory of Open Access Journals (Sweden)

    Zainal Abidin Mohd Hazreek


    Full Text Available Electrical resistivity method has increasingly adopted in engineering, environmental, mining and archaeological studies. Systematic and proper studies of unknown civil engineering structure evaluation particularly on tube well depth was rarely being established. Conventionally, camera test or string with weight approach has been used to evaluate unknown tube well depth thus exposed to several restriction due to its expensive and time consuming. Hence, this study focused on evaluation of unknown tube well depth using indirect test with particular reference to electrical resistivity method (ERM.A single spread line of electrical resistivity survey was performed using ABEM SAS 4000 equipment set based on Wenner and Pole-dipole array in line with the tube well position. Electrical resistivity raw data was processed using RES2DINV software producing electrical resistivity tomography (ERT of the subsurface profile studied. Then, electrical resistivity value (ERV obtained from RES2DINV analyses (ERT was extracted and analysed using plotted graph (depth versus ERV specifically at tube well position based on electrical resistivity spread line performed. It was found that both array have shown some good similarity results in term of tube well depth (20 m thus able to verify the result interpreted. Both array have shown some good similarity of ERV representing groundwater (ERV = 10 – 100 Ωm and soil with water (ERV > 100 Ωm at depth of 0 – 20 m and >20 m respectively. All those interpretation have shown good agreement based on verification thru established ERV of earth materials references, geological map and nearest available boreholes data. Hence, this study has shown that the application of ERM was applicable in evaluation of unknown tube well depth which efficient in term of cost, time and environmental sustainable.

  9. Renovation of the Tomb of the Unknown Soldier, Baghdad, Iraq (United States)


    animals, including some of the “ pet ” lions kept by Uday and Qusay Hussein. Also located near the Tomb of the Unknown in the Al Zarwaa Park is an...the following: 4 x 800 amp automatic transfer switches main power boards sub-distribution board for the different facilities main feeder ...repairing the 3-phase diesel generator and installing automatic transfer switches, main power boards, main feeder cables, and interior and exterior

  10. Stability Analysis of Fractional Differential Equations with Unknown Parameters


    Koksal, Mehmet Emir


    In this paper, the stability of fractional differential equations (FDEs) with unknown parameters is studied. FDEs bring many advantages to model the physical systems in the nature or man-made systems in the industry. Because this representation has a property between linear differential equations and nonlinear differential equations. Therefore, the designer may use the FDEs to model complex systems instead of nonlinear differential equations which have hard mathematical background. Using the ...

  11. Modal Parameter Identification from Responses of General Unknown Random Inputs


    Ibrahim, S. R.; Asmussen, J. C.; Brincker, Rune


    Modal parameter identification from ambient responses due to a general unknown random inputs is investigated. Existing identification techniques which are based on assumptions of white noise and or stationary random inputs are utilized even though the inputs conditions are not satisfied. This is accomplished via adding. In cascade. A force cascade conversion to the structures system under consideration. The input to the force conversion system is white noise and the output of which is the act...

  12. Localized hepatic tuberculosis presenting as fever of unknown origin

    Directory of Open Access Journals (Sweden)

    Teresa Cristina Abreu Ferrari

    Full Text Available Localized hepatic tuberculosis is a rare clinical form of tuberculosis infection; it has signs and symptoms related only to hepatic injury, with minimal or no extrahepatic involvement. It frequently presents as a non-specific syndrome, with systemic manifestations, which can sometimes result in a diagnostic dilemma. A high index of suspicion is required and a definitive diagnosis can be very difficult. We report a case of localized hepatic tuberculosis that presented as fever of unknown origin.

  13. General Unknown Screening by Ion Trap LC/MS/MS (United States)


    are collected at autopsy and sent to CAMI’s Forensic Toxicology Research Laboratory for toxicological analysis of various postmortem fluids and... Forensic Toxicology, General Unknown Screening, LC/MS Document is available to the public through the Defense Technical Information...resulting in an acid/ neutral and a base vial from each specimen. rEsulTs ANd dIsCussION This study established the LOD for 359 forensically

  14. Technologies and Mission Concepts for NHST (United States)

    Oegerle, William R.


    A technology workshop entitled "Innovative Designs for the Next Large Aperture Optical/UV Telescope" was held on April 10-11 at the Space Telescope Science Institute in Baltimore. This workshop was held to consider the technologies that will be required to support optical/UV space missions designed to carry out the science envisioned by the Hubble Science Legacy meeting held in April 2002 in Chicago. Subjects covered at the workshop included: optical designs, wavefront control, mirror technologies, spectrographs, coronagraphs, detector technologies, and in-space construction. A summary of the workshop and near-term plans for investigating several mission concepts will be provided. Funding for this workshop was provided by NASA.

  15. The mission of a philosophical discourse

    Directory of Open Access Journals (Sweden)

    José Ricardo Perfecto Sánchez


    Full Text Available Attending to the inivitation for participating into the First International Seminary on Conflict Resolution and Peace Construction, we decided to inquire and write on “The mission of philosophical speech about Peace Construction, because we think that is more important to talk about social phenomenon of peace than about social phenomenon of violence, in spite of the tendency of investigating is to study violent facts. In our case, we have preferred to choose for examination and support the proposal of Alfono Fernández Herrería and Mary del Carmen López López on System-Complex Epistemology to built peace. At the same time we follow the Antropic Philosophy of Tomaso Bugossi in order to describe next points: an integral concept of human being like subject-person, distinction among Philosophy and philosophies, mission of a philosophical speech and construction of peace.

  16. Hayabusa2 Mission Overview (United States)

    Watanabe, Sei-ichiro; Tsuda, Yuichi; Yoshikawa, Makoto; Tanaka, Satoshi; Saiki, Takanao; Nakazawa, Satoru


    The Hayabusa2 mission journeys to C-type near-Earth asteroid (162173) Ryugu (1999 JU3) to observe and explore the 900 m-sized object, as well as return samples collected from the surface layer. The Haybusa2 spacecraft developed by Japan Aerospace Exploration Agency (JAXA) was successfully launched on December 3, 2014 by an H-IIA launch vehicle and performed an Earth swing-by on December 3, 2015 to set it on a course toward its target Ryugu. Hayabusa2 aims at increasing our knowledge of the early history and transfer processes of the solar system through deciphering memories recorded on Ryugu, especially about the origin of water and organic materials transferred to the Earth's region. Hayabusa2 carries four remote-sensing instruments, a telescopic optical camera with seven colors (ONC-T), a laser altimeter (LIDAR), a near-infrared spectrometer covering the 3-μm absorption band (NIRS3), and a thermal infrared imager (TIR). It also has three small rovers of MINERVA-II and a small lander MASCOT (Mobile Asteroid Surface Scout) developed by German Aerospace Center (DLR) in cooperation with French space agency CNES. MASCOT has a wide angle imager (MasCam), a 6-band thermal radiator (MARA), a 3-axis magnetometer (MasMag), and a hyperspectral infrared microscope (MicrOmega). Further, Hayabusa2 has a sampling device (SMP), and impact experiment devices which consist of a small carry-on impactor (SCI) and a deployable camera (DCAM3). The interdisciplinary research using the data from these onboard and lander's instruments and the analyses of returned samples are the key to success of the mission.

  17. The Messenger Mission to Mercury

    CERN Document Server

    Domingue, D. L


    NASA’s MESSENGER mission, launched on 3 August, 2004 is the seventh mission in the Discovery series. MESSENGER encounters the planet Mercury four times, culminating with an insertion into orbit on 18 March 2011. It carries a comprehensive package of geophysical, geological, geochemical, and space environment experiments to complete the complex investigations of this solar-system end member, which begun with Mariner 10. The articles in this book, written by the experts in each area of the MESSENGER mission, describe the mission, spacecraft, scientific objectives, and payload. The book is of interest to all potential users of the data returned by the MESSENGER mission, to those studying the nature of the planet Mercury, and by all those interested in the design and implementation of planetary exploration missions.

  18. Improving Life-Cycle Cost Management of Spacecraft Missions (United States)

    Clardy, Dennon


    This presentation will explore the results of a recent NASA Life-Cycle Cost study and how project managers can use the findings and recommendations to improve planning and coordination early in the formulation cycle and avoid common pitfalls resulting in cost overruns. The typical NASA space science mission will exceed both the initial estimated and the confirmed life-cycle costs by the end of the mission. In a fixed-budget environment, these overruns translate to delays in starting or launching future missions, or in the worst case can lead to cancelled missions. Some of these overruns are due to issues outside the control of the project; others are due to the unpredictable problems (unknown unknowns) that can affect any development project. However, a recent study of life-cycle cost growth by the Discovery and New Frontiers Program Office identified a number of areas that are within the scope of project management to address. The study also found that the majority of the underlying causes for cost overruns are embedded in the project approach during the formulation and early design phases, but the actual impacts typically are not experienced until late in the project life cycle. Thus, project management focus in key areas such as integrated schedule development, management structure and contractor communications processes, heritage and technology assumptions, and operations planning, can be used to validate initial cost assumptions and set in place management processes to avoid the common pitfalls resulting in cost overruns.

  19. Nonlinear Integral Type Observer Design for State Estimation and Unknown Input Reconstruction

    Directory of Open Access Journals (Sweden)

    Chao-Chung Peng


    Full Text Available This paper is concerned with model-based robust observer designs for state observation and its application for unknown input reconstruction. Firstly, a sliding mode observer (SMO, which provides exponential convergence of estimation error, is designed for a class of multivariable perturbed systems. Observer gain matrices subject to specific structures are going to be imposed such that the unknown perturbation will not affect estimate precision during the sliding modes; Secondly, to improve discontinuous control induced in the SMO as well as pursue asymptotic estimate precision, a proportional-integral type observer (PIO is further developed. Both the design procedures of the SMO and PIO algorithms are characterized as feasibility issues of linear matrix inequality (LMI and thus the computations of the control parameters can be efficiently solved. Compared with the SMO, it will be demonstrated that the PIO is capable of achieving better estimation precision as long as the unknown inputs are continuous. Finally, a servo-drive flexible robot arm is selected as an example to demonstrate the applications of the robust observer designs.

  20. Restoring accents in unknown biomedical words: application to the French MeSH thesaurus. (United States)

    Zweigenbaum, Pierre; Grabar, Natalia


    In languages with diacritic marks, such as French, there remain instances of textual or terminological resources that are available in electronic form without diacritic marks, which hinders their use in natural language interfaces. In a specialized domain such as medicine, it is often the case that some words are not found in the available electronic lexicons. The issue of accenting unknown words then arises: it is the theme of this work. We propose two internal methods for accenting unknown words, which both learn on a reference set of accented words the contexts of occurrence of the various accented forms of a given letter. One method is adapted from part-of-speech tagging, the other is based on finite state transducers. We show experimental results for letter e on the French version of the Medical Subject Headings thesaurus. With the best training set, the tagging method obtains a precision-recall breakeven point of 84.2+/-4.4% and the transducer method 83.8+/-4.5% (with a baseline at 64%) for the unknown words that contain this letter. A consensus combination of both increases precision to 92.0+/-3.7% with a recall of 75%. We perform an error analysis and discuss further steps that might help improve over the current performance.

  1. NASA's Asteroid Redirect Mission (ARM) (United States)

    Abell, Paul; Mazanek, Dan; Reeves, David; Naasz, Bo; Cichy, Benjamin


    The National Aeronautics and Space Administration (NASA) is developing a robotic mission to visit a large near-Earth asteroid (NEA), collect a multi-ton boulder from its surface, and redirect it into a stable orbit around the Moon. Once returned to cislunar space in the mid-2020s, astronauts will explore the boulder and return to Earth with samples. This Asteroid Redirect Mission (ARM) is part of NASA’s plan to advance the technologies, capabilities, and spaceflight experience needed for a human mission to the Martian system in the 2030s. Subsequent human and robotic missions to the asteroidal material would also be facilitated by its return to cislunar space. Although ARM is primarily a capability demonstration mission (i.e., technologies and associated operations), there exist significant opportunities to advance our knowledge of small bodies in the synergistic areas of science, planetary defense, asteroidal resources and in-situ resource utilization (ISRU), and capability and technology demonstrations. In order to maximize the knowledge return from the mission, NASA is organizing an ARM Investigation Team, which is being preceded by the Formulation Assessment and Support Team. These teams will be comprised of scientists, technologists, and other qualified and interested individuals to help plan the implementation and execution of ARM. An overview of robotic and crewed segments of ARM, including the mission requirements, NEA targets, and mission operations, will be provided along with a discussion of the potential opportunities associated with the mission.

  2. Short-term Internet search using makes people rely on search engines when facing unknown issues. (United States)

    Wang, Yifan; Wu, Lingdan; Luo, Liang; Zhang, Yifen; Dong, Guangheng


    The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day's training of Internet search, and a post-test. During the pre- and post- tests, subjects were asked to search online the answers to 40 unusual questions, remember the answers and recall them in the scanner. Un-learned questions were randomly presented at the recalling stage in order to elicited search impulse. Comparing to the pre-test, subjects in the post-test reported higher impulse to use search engines to answer un-learned questions. Consistently, subjects showed higher brain activations in dorsolateral prefrontal cortex and anterior cingulate cortex in the post-test than in the pre-test. In addition, there were significant positive correlations self-reported search impulse and brain responses in the frontal areas. The results suggest that a simple six-day's Internet search training can make people dependent on the search tools when facing unknown issues. People are easily dependent on the Internet search engines.

  3. Short-term Internet search using makes people rely on search engines when facing unknown issues.

    Directory of Open Access Journals (Sweden)

    Yifan Wang

    Full Text Available The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day's training of Internet search, and a post-test. During the pre- and post- tests, subjects were asked to search online the answers to 40 unusual questions, remember the answers and recall them in the scanner. Un-learned questions were randomly presented at the recalling stage in order to elicited search impulse. Comparing to the pre-test, subjects in the post-test reported higher impulse to use search engines to answer un-learned questions. Consistently, subjects showed higher brain activations in dorsolateral prefrontal cortex and anterior cingulate cortex in the post-test than in the pre-test. In addition, there were significant positive correlations self-reported search impulse and brain responses in the frontal areas. The results suggest that a simple six-day's Internet search training can make people dependent on the search tools when facing unknown issues. People are easily dependent on the Internet search engines.

  4. Simulation of Mission Phases (United States)

    Carlstrom, Nicholas Mercury


    This position with the Simulation and Graphics Branch (ER7) at Johnson Space Center (JSC) provided an introduction to vehicle hardware, mission planning, and simulation design. ER7 supports engineering analysis and flight crew training by providing high-fidelity, real-time graphical simulations in the Systems Engineering Simulator (SES) lab. The primary project assigned by NASA mentor and SES lab manager, Meghan Daley, was to develop a graphical simulation of the rendezvous, proximity operations, and docking (RPOD) phases of flight. The simulation is to include a generic crew/cargo transportation vehicle and a target object in low-Earth orbit (LEO). Various capsule, winged, and lifting body vehicles as well as historical RPOD methods were evaluated during the project analysis phase. JSC core mission to support the International Space Station (ISS), Commercial Crew Program (CCP), and Human Space Flight (HSF) influenced the project specifications. The simulation is characterized as a 30 meter +V Bar and/or -R Bar approach to the target object's docking station. The ISS was selected as the target object and the international Low Impact Docking System (iLIDS) was selected as the docking mechanism. The location of the target object's docking station corresponds with the RPOD methods identified. The simulation design focuses on Guidance, Navigation, and Control (GNC) system architecture models with station keeping and telemetry data processing capabilities. The optical and inertial sensors, reaction control system thrusters, and the docking mechanism selected were based on CCP vehicle manufacturer's current and proposed technologies. A significant amount of independent study and tutorial completion was required for this project. Multiple primary source materials were accessed using the NASA Technical Report Server (NTRS) and reference textbooks were borrowed from the JSC Main Library and International Space Station Library. The Trick Simulation Environment and User

  5. First Results from the DAMPE Mission

    CERN Document Server

    CERN. Geneva


    DAMPE (DArk Matter Particle Explorer) is a satellite mission of the Chinese Academy of Sciences (CAS) dedicated to high energy cosmic ray detections. Since its successful launch on December 17th, 2015 a large amount of cosmic ray data has been collected. With relatively large acceptance, DAMPE is designed to detect electrons (and positrons) up to 10 TeV with unprecedented energy resolution to search for new features in the cosmic ray electron plus positron (CRE) spectrum. It will also study cosmic ray nuclei up to 100 TeV with good precision, which will bring new input to the study of their still unknown origin and their propagation through the Galaxy. In this talk, the DAMPE mission will be introduced, together with some details of the construction and on-ground calibration of the detector subsystems. The in-orbit detector commissioning, calibration and operation will be described. First data analysis results, including the recently published CRE spectrum from 25 GeV to 4.6 TeV based on the data collected i...

  6. Combining meteorites and missions to explore Mars. (United States)

    McCoy, Timothy J; Corrigan, Catherine M; Herd, Christopher D K


    Laboratory studies of meteorites and robotic exploration of Mars reveal scant atmosphere, no evidence of plate tectonics, past evidence for abundant water, and a protracted igneous evolution. Despite indirect hints, direct evidence of a martian origin came with the discovery of trapped atmospheric gases in one meteorite. Since then, the study of martian meteorites and findings from missions have been linked. Although the meteorite source locations are unknown, impact ejection modeling and spectral mapping of Mars suggest derivation from small craters in terrains of Amazonian to Hesperian age. Whereas most martian meteorites are young ( 4.5 Ga and formation of enriched and depleted reservoirs. However, the history inferred from martian meteorites conflicts with results from recent Mars missions, calling into doubt whether the igneous histor y inferred from the meteorites is applicable to Mars as a whole. Allan Hills 84001 dates to 4.09 Ga and contains fluid-deposited carbonates. Accompanying debate about the mechanism and temperature of origin of the carbonates came several features suggestive of past microbial life in the carbonates. Although highly disputed, the suggestion spurred interest in habitable extreme environments on Earth and throughout the Solar System. A flotilla of subsequent spacecraft has redefined Mars from a volcanic planet to a hydrologically active planet that may have harbored life. Understanding the history and habitability of Mars depends on understanding the coupling of the atmosphere, surface, and subsurface. Sample return that brings back direct evidence from these diverse reservoirs is essential.

  7. An Evidence-Based Review Literature About Risk Indicators and Management of Unknown-Origin Xerostomia

    Directory of Open Access Journals (Sweden)

    Farzaneh Agha-hosseini


    Full Text Available Objective: This evidence-based article reviews risk indicators and management of unknown-origin xerostomia. Xerostomia and hyposalivation refer to different aspects of dry mouth. Xerostomia is a subjective sensation of dry mouth, whilst hyposalivation is defined as an objective assessment of reduced salivary flow rate. About 30% of the elderly (65 years and older experience xerostomia and hyposalivation. Structural and functional factors, or both may lead to salivary gland dysfunction.Study Selection: The EBM literature search was conducted by using the medical literature database MEDLINE via PubMed and OvidMedline search engines. Results were limited to English language articles (1965 to present including clinical trials (CT, randomized controlled trials (RCT, systematic reviews and review articles. Case control or cohort studies were included for the etiology.Results: Neuropathic etiology such as localized oral alteration of thermal sensations, saliva composition change (for example higher levels of K, Cl, Ca, IgA, amylase, calcium, PTH and cortisol, lower levels of estrogen and progesterone, smaller salivary gland size, and illnesses such as lichen planus, are risk indicators for unknown-origin xerostomia. The management is palliative and preventative. Management of symptoms includes drug administration (systemic secretogogues, saliva substitutes and bile secretion-stimulator, night guard, diet and habit modifications. Other managements may be indicated to treat adverse effects.Conclusion: Neuropathic etiology, saliva composition change, smaller salivary gland size, and illnesses such as oral lichen planus can be suggestive causes for unknown-origin xerostomia. However, longitudinal studies will be important to elucidate the causes of unknown-origin xerostomia.

  8. An Evidence-Based Review Literature About Risk Indicators and Management of Unknown-Origin Xerostomia (United States)

    Agha-Hosseini, Farzaneh; Moosavi, Mahdieh-Sadat


    This evidence-based article reviews risk indicators and management of unknown-origin xerostomia. Xerostomia and hyposalivation refer to different aspects of dry mouth. Xerostomia is a subjective sensation of dry mouth, whilst hyposalivation is defined as an objective assessment of reduced salivary flow rate. About 30% of the elderly (65 years and older) experience xerostomia and hyposalivation. Structural and functional factors, or both may lead to salivary gland dysfunction. The EBM literature search was conducted by using the medical literature database MEDLINE via PubMed and OvidMedline search engines. Results were limited to English language articles (1965 to present) including clinical trials (CT), randomized controlled trials (RCT), systematic reviews and review articles. Case control or cohort studies were included for the etiology. Neuropathic etiology such as localized oral alteration of thermal sensations, saliva composition change (for example higher levels of K, Cl, Ca, IgA, amylase, calcium, PTH and cortisol), lower levels of estrogen and progesterone, smaller salivary gland size, and illnesses such as lichen planus, are risk indicators for unknown-origin xerostomia. The management is palliative and preventative. Management of symptoms includes drug administration (systemic secretogogues, saliva substitutes and bile secretion-stimulator), night guard, diet and habit modifications. Other managements may be indicated to treat adverse effects. Neuropathic etiology, saliva composition change, smaller salivary gland size, and illnesses such as oral lichen planus can be suggestive causes for unknown-origin xerostomia. However, longitudinal studies will be important to elucidate the causes of unknown-origin xerostomia. PMID:25512755

  9. Subjective Evaluations: Discretionary Bonuses and Feedback Credibility


    Fuchs, William


    We provide a new rationale for the use of discretionary bonuses. In a setting with unknown match qualities between a worker and a firm and subjective evaluations by the principal, bonuses are useful in order to make the feedback from the firm to the workers credible. This way workers in good matches are less inclined to accept outside offers.

  10. [The identification of unknown corpses by x-ray comparison]. (United States)

    Riepert, T; Schweden, F; Schild, H; Rittner, C


    Between 1987 and 1993, 30 unknown bodies were identified by means of pre- and postmortem radiographs at the Forensic Institute in Mainz. Our experience indicates that radiological identification comprises a useful, rapid and cheap method, at least as valuable as dactyloscopy or odontological comparisons. The ages of available radiographs were up to 25 years; the most suitable regions are the skull (11), pelvis and lumbar spine (6), lower femur and knee (5) and distal leg with the ankle joint (5). In respect of the problem of objectifying the probability of identity, possibilities for solutions are shown.

  11. Anal Cancer debuting as Cancer of Unknown Primary

    DEFF Research Database (Denmark)

    Sveistrup, Joen; Loft, Annika; Engelholm, Svend Aage


    Anal cancer usually presents with a visible or palpable tumour. In this case we describe a 54-year old man diagnosed with Cancer of Unknown Primary (CUP) with a single inguinal node as the only finding. Thorough examination failed to identify any primary tumour. The patient was treated with lymph...... node dissection and not until nearly two years after initial diagnosis, was the primary tumour found, and the patient was diagnosed with anal cancer. The patient was treated with chemoradiotherapy and 45 months after initial diagnosis there is still no sign of relapse. This case illustrates, that anal...

  12. Fault tolerant control of wind turbines using unknown input observers

    DEFF Research Database (Denmark)

    Odgaard, Peter Fogh; Stoustrup, Jakob


    This paper presents a scheme for accommodating faults in the rotor and generator speed sensors in a wind turbine. These measured values are important both for the wind turbine controller as well as the supervisory control of the wind turbine. The scheme is based on unknown input observers, which ...... are also used to detect and isolate these faults. The scheme is tested on a known benchmark for FDI and FTC of wind turbines. Tests on this benchmark model show a clear potential of the proposed scheme....

  13. The AGILE Mission

    CERN Document Server

    Tavani, M.; Argan, A.; Boffelli, F.; Bulgarelli, A.; Caraveo, P.; Cattaneo, P.W.; Chen, A.W.; Cocco, V.; Costa, E.; D'Ammando, F.; Del Monte, E.; De Paris, G.; Di Cocco, G.; Di Persio, G.; Donnarumma, I.; Evangelista, Y.; Feroci, M.; Ferrari, A.; Fiorini, M.; Fornari, F.; Fuschino, F.; Froysland, T.; Frutti, M.; Galli, M.; Gianotti, F.; Giuliani, A.; Labanti, C.; Lapshov, I.; Lazzarotto, F.; Liello, F.; Lipari, P.; Longo, F.; Mattaini, E.; Marisaldi, M.; Mastropietro, M.; Mauri, A.; Mauri, F.; Mereghetti, S.; Morelli, E.; Morselli, A.; Pacciani, L.; Pellizzoni, A.; Perotti, F.; Piano, G.; Picozza, P.; Pontoni, C.; Porrovecchio, G.; Prest, M.; Pucella, G.; Rapisarda, M.; Rappoldi, A.; Rossi, E.; Rubini, A.; Soffitta, P.; Traci, A.; Trifoglio, M.; Trois, A.; Vallazza, E.; Vercellone, S.; Vittorini, V.; Zambra, A.; Zanello, D.; Pittori, C.; Preger, B.; Santolamazza, P.; Verrecchia, F.; Giommi, P.; Colafrancesco, S.; Antonelli, A.; Cutini, S.; Gasparrini, D.; Stellato, S.; Fanari, G.; Primavera, R.; Tamburelli, F.; Viola, F.; Guarrera, G.; Salotti, L.; D'Amico, F.; Marchetti, E.; Crisconio, M.; Sabatini, P.; Annoni, G.; Alia, S.; Longoni, A.; Sanquerin, R.; Battilana, M.; Concari, P.; Dessimone, E.; Grossi, R.; Parise, A.; Monzani, F.; Artina, E.; Pavesi, R.; Marseguerra, G.; Nicolini, L.; Scandelli, L.; Soli, L.; Vettorello, V.; Zardetto, E.; Bonati, A.; Maltecca, L.; D'Alba, E.; Patane, M.; Babini, G.; Onorati, F.; Acquaroli, L.; Angelucci, M.; Morelli, B.; Agostara, C.; Cerone, M.; Michetti, A.; Tempesta, P.; D'Eramo, S.; Rocca, F.; Giannini, F.; Borghi, G.; Garavelli, B.; Conte, M.; Balasini, M.; Ferrario, I.; Vanotti, M.; Collavo, E.; Giacomazzo, M.


    AGILE is an Italian Space Agency mission dedicated to the observation of the gamma-ray Universe. The AGILE very innovative instrumentation combines for the first time a gamma-ray imager (sensitive in the energy range 30 MeV - 50 GeV), a hard X-ray imager (sensitive in the range 18-60 keV) together with a Calorimeter (sensitive in the range 300 keV - 100 MeV) and an anticoincidence system. AGILE was successfully launched on April 23, 2007 from the Indian base of Sriharikota and was inserted in an equatorial orbit with a very low particle background. AGILE provides crucial data for the study of Active Galactic Nuclei, Gamma-Ray Bursts, pulsars, unidentified gamma-ray sources, Galactic compact objects, supernova remnants, TeV sources, and fundamental physics by microsecond timing. An optimal angular resolution (reaching 0.1-0.2 degrees in gamma-rays, 1-2 arcminutes in hard X-rays) and very large fields of view (2.5 sr and 1 sr, respectively) are obtained by the use of Silicon detectors integrated in a very compa...

  14. The PLATO Mission (United States)

    Rauer, Heike


    PLATO (PLAnetary Transits and Oscillations of stars) has been selected for ESA's M3 launch opportunity end 2025. PLATO will carry out high-precision, long-term photometric and asteroseismic monitoring of a large number of stars. It will provide a large sample of small planets around bright stars, including terrestrial planets in the habitable zone of solar-like stars. PLATO will characterize planets for their radius, mass, and age with high accuracy. PLATO will provide the first large-scale catalogue of well-characterized small planets at intermediate orbital periods, which will be an important constraint to planet formation theories and will provide targets for future atmosphere spectroscopy follow-up observations. This data base of bulk characterized small planets will form a solid basis to put the Solar System into a wider context and allow for comparative exo-planetology. In addition, the precise stellar parameters obtained by asteroseismic studies will open new doors to better understand stellar interiors and allow us to constrain poorly-understood physical processes, like convection, improve our understanding of stellar evolution, and determine precise ages of stars and planetary systems. The talk will provide an overview of the current status of the PLATO mission and focus on its science goals.

  15. Urinary albumin in space missions

    DEFF Research Database (Denmark)

    Cirillo, Massimo; De Santo, Natale G; Heer, Martina


    Proteinuria was hypothesized for space mission but research data are missing. Urinary albumin, as index of proteinuria, was analyzed in frozen urine samples collected by astronauts during space missions onboard MIR station and on ground (control). Urinary albumin was measured by a double antibody...

  16. The future of NASA's missions (United States)

    A'Hearn, Michael F.


    Can the recent Discovery mission selections be used as tea leaves to understand the future directions of NASA? In an age of many programmes being used to advance administrative and programmatic goals, Discovery appears to be driven almost entirely by science and by NASA's goal of cheaper missions.

  17. The Asteroid Redirect Mission (ARM) (United States)

    Abell, P. A.; Mazanek, D. D.; Reeves, D. M.; Chodas, P. W.; Gates, M. M.; Johnson, L. N.; Ticker, R. L.


    To achieve its long-term goal of sending humans to Mars, the National Aeronautics and Space Administration (NASA) plans to proceed in a series of incrementally more complex human spaceflight missions. Today, human flight experience extends only to Low-Earth Orbit (LEO), and should problems arise during a mission, the crew can return to Earth in a matter of minutes to hours. The next logical step for human spaceflight is to gain flight experience in the vicinity of the Moon. These cis-lunar missions provide a "proving ground" for the testing of systems and operations while still accommodating an emergency return path to the Earth that would last only several days. Cis-lunar mission experience will be essential for more ambitious human missions beyond the Earth- Moon system, which will require weeks, months, or even years of transit time.

  18. Range image registration using a photometric metric under unknown lighting. (United States)

    Thomas, Diego; Sugimoto, Akihiro


    Based on the spherical harmonics representation of image formation, we derive a new photometric metric for evaluating the correctness of a given rigid transformation aligning two overlapping range images captured under unknown, distant, and general illumination. We estimate the surrounding illumination and albedo values of points of the two range images from the point correspondences induced by the input transformation. We then synthesize the color of both range images using albedo values transferred using the point correspondences to compute the photometric reprojection error. This way allows us to accurately register two range images by finding the transformation that minimizes the photometric reprojection error. We also propose a practical method using the proposed photometric metric to register pairs of range images devoid of salient geometric features, captured under unknown lighting. Our method uses a hypothesize-and-test strategy to search for the transformation that minimizes our photometric metric. Transformation candidates are efficiently generated by employing the spherical representation of each range image. Experimental results using both synthetic and real data demonstrate the usefulness of the proposed metric.

  19. Shading-based Surface Detail Recovery under General Unknown Illumination. (United States)

    Xu, Di; Duan, Qi; Zheng, Jianmin; Zhang, Juyong; Cai, Jianfei; Cham, Tat-Jen


    Reconstructing the shape of a 3D object from multi-view images under unknown, general illumination is a fundamental problem in computer vision and high quality reconstruction is usually challenging especially when fine detail is needed and the albedo of the object is non-uniform. This paper introduces vertex overall illumination vectors to model the illumination effect and presents a total variation (TV) based approach for recovering surface details using shading and multi-view stereo (MVS). Behind the approach are the two important observations: (1) the illumination over the surface of an object often appears to be piece wise smooth and (2) the recovery of surface orientation is not sufficient for reconstructing the surface, which was often overlooked previously. Thus we propose to use TV to regularize the overall illumination vectors and use visual hull to constrain partial vertices. The reconstruction is formulated as a constrained TV-minimization problem that simultaneously treats the shape and illumination vectors as unknowns. An augmented Lagrangian method is proposed to quickly solve the TV-minimization problem. As a result, our approach is robust, stable and is able to efficiently recover high quality of surface details even when starting with a coarse model obtained using MVS. These advantages are demonstrated by extensive experiments on the state-of-the-art MVS database, which includes challenging objects with varying albedo.

  20. The random exploration graph for optimal exploration of unknown environments

    Directory of Open Access Journals (Sweden)

    Alfredo Toriz Palacios


    Full Text Available The exploration of an unknown environment by a robot system is a well-studied problem in robotics; however, although many of the proposals made in this field represent efficient tools in terms of exploration paradigm, most of them are not efficient for time critical applications since the robot may visit the same place more than once during backtracking. In this way and considering these limitations, this article presents a novel approach called the random exploration graph, which addresses the problem of exploring unknown environments by building a graph structure created incrementally by the random choice of the free frontier in the observation range of the robot. In addition, the random exploration graph algorithm uses a new concept called “frontier control” introduced in this work, used to store nodes left behind in the graph structure that have not been fully explored and that will be used to guide the exploration process in an efficient way, when the algorithm needs to go back to previously visited areas to continue exploration. The frontier control concept next to the versatility of the graph structure used for the exploration process is the main contribution of this work.

  1. Reactive Path Planning Approach for Docking Robots in Unknown Environment

    Directory of Open Access Journals (Sweden)

    Peng Cui


    Full Text Available Autonomous robots need to be recharged and exchange information with the host through docking in the long-distance tasks. Therefore, feasible path is required in the docking process to guide the robot and adjust its pose. However, when there are unknown obstacles in the work area, it becomes difficult to determine the feasible path for docking. This paper presents a reactive path planning approach named Dubins-APF (DAPF to solve the path planning problem for docking in unknown environment with obstacles. In this proposed approach the Dubins curves are combined with the designed obstacle avoidance potential field to plan the feasible path. Firstly, an initial path is planned and followed according to the configurations of the robot and the docking station. Then when the followed path is evaluated to be infeasible, the intermediate configuration is calculated as well as the replanned path based on the obstacle avoidance potential field. The robot will be navigated to the docking station with proper pose eventually via the DAPF approach. The proposed DAPF approach is efficient and does not require the prior knowledge about the environment. Simulation results are given to validate the effectiveness and feasibility of the proposed approach.

  2. Three-dimensional cinematography with control object of unknown shape. (United States)

    Dapena, J; Harman, E A; Miller, J A


    A technique for reconstruction of three-dimensional (3D) motion which involves a simple filming procedure but allows the deduction of coordinates in large object volumes was developed. Internal camera parameters are calculated from measurements of the film images of two calibrated crosses while external camera parameters are calculated from the film images of points in a control object of unknown shape but at least one known length. The control object, which includes the volume in which the activity is to take place, is formed by a series of poles placed at unknown locations, each carrying two targets. From the internal and external camera parameters, and from locations of the images of point in the films of the two cameras, 3D coordinates of the point can be calculated. Root mean square errors of the three coordinates of points in a large object volume (5m x 5m x 1.5m) were 15 mm, 13 mm, 13 mm and 6 mm, and relative errors in lengths averaged 0.5%, 0.7% and 0.5%, respectively.

  3. Learned navigation in unknown terrains: A retraction method (United States)

    Rao, Nageswara S. V.; Stoltzfus, N.; Iyengar, S. Sitharama


    The problem of learned navigation of a circular robot R, of radius delta (is greater than or equal to 0), through a terrain whose model is not a-priori known is considered. Two-dimensional finite-sized terrains populated by an unknown (but, finite) number of simple polygonal obstacles are also considered. The number and locations of the vertices of each obstacle are unknown to R. R is equipped with a sensor system that detects all vertices and edges that are visible from its present location. In this context two problems are covered. In the visit problem, the robot is required to visit a sequence of destination points, and in the terrain model acquisition problem, the robot is required to acquire the complete model of the terrain. An algorithmic framework is presented for solving these two problems using a retraction of the freespace onto the Voronoi diagram of the terrain. Algorithms are then presented to solve the visit problem and the terrain model acquisition problem.

  4. Multi-mission Satellite Management (United States)

    Jamilkowski, M. L.; Teter, M. A.; Grant, K. D.; Dougherty, B.; Cochran, S.


    NOAA's next-generation environmental satellite, the Joint Polar Satellite System (JPSS) replaces the current Polar-orbiting Operational Environmental Satellites (POES). JPSS satellites carry sensors which collect meteorological, oceanographic, climatological, and solar-geophysical observations of the earth, atmosphere, and space. The first JPSS satellite was launched in 2011 and is currently NOAA's primary operational polar satellite. The JPSS ground system is the Common Ground System (CGS), and provides command, control, and communications (C3) and data processing (DP). A multi-mission system, CGS provides combinations of C3/DP for numerous NASA, NOAA, DoD, and international missions. In preparation for the next JPSS satellite, CGS improved its multi-mission capabilities to enhance mission operations for larger constellations of earth observing satellites with the added benefit of streamlining mission operations for other NOAA missions. CGS's multi-mission capabilities allows management all of assets as a single enterprise, more efficiently using ground resources and personnel and consolidating multiple ground systems into one. Sophisticated scheduling algorithms compare mission priorities and constraints across all ground stations, creating an enterprise schedule optimized to mission needs, which CGS executes to acquire the satellite link, uplink commands, downlink and route data to the operations and data processing facilities, and generate the final products for delivery to downstream users. This paper will illustrate the CGS's ability to manage multiple, enterprise-wide polar orbiting missions by demonstrating resource modeling and tasking, production of enterprise contact schedules for NOAA's Fairbanks ground station (using both standing and ad hoc requests), deconflicting resources due to ground outages, and updating resource allocations through dynamic priority definitions.

  5. Tracking consensus for nonlinear heterogeneous multi-agent systems subject to unknown disturbances via sliding mode control (United States)

    Zhang, Xiang; Wang, Jin-Huan; Yang, De-Dong; Xu, Yong


    Not Available Project supported by the National Natural Science Foundation of China (Grant No. 61203142) and the Natural Science Foundation of Hebei Province, China (Grant Nos. F2014202206 and F2017202009).

  6. Radioisotope Power Systems Reference Book for Mission Designers and Planners (United States)

    Lee, Young; Bairstow, Brian


    The RPS Program's Program Planning and Assessment (PPA) Office commissioned the Mission Analysis team to develop the Radioisotope Power Systems (RPS) Reference Book for Mission Planners and Designers to define a baseline of RPS technology capabilities with specific emphasis on performance parameters and technology readiness. The main objective of this book is to provide RPS technology information that could be utilized by future mission concept studies and concurrent engineering practices. A progress summary from the major branches of RPS technology research provides mission analysis teams with a vital tool for assessing the RPS trade space, and provides concurrent engineering centers with a consistent set of guidelines for RPS performance characteristics. This book will be iterated when substantial new information becomes available to ensure continued relevance, serving as one of the cornerstone products of the RPS PPA Office. This book updates the original 2011 internal document, using data from the relevant publicly released RPS technology references and consultations with RPS technologists. Each performance parameter and RPS product subsection has been reviewed and cleared by at least one subject matter representative. A virtual workshop was held to reach consensus on the scope and contents of the book, and the definitions and assumptions that should be used. The subject matter experts then reviewed and updated the appropriate sections of the book. The RPS Mission Analysis Team then performed further updates and crosschecked the book for consistency. Finally, a second virtual workshop was held to ensure all subject matter experts and stakeholders concurred on the contents.


    Energy Technology Data Exchange (ETDEWEB)



    Identifying functions for all gene products in all sequenced organisms is a central challenge of the post-genomic era. However, at least 30-50% of the proteins encoded by any given genome are of unknown function, or wrongly or vaguely annotated. Many of these 'unknown' proteins are common to prokaryotes and plants. We accordingly set out to predict and experimentally test the functions of such proteins. Our approach to functional prediction is integrative, coupling the extensive post-genomic resources available for plants with comparative genomics based on hundreds of microbial genomes, and functional genomic datasets from model microorganisms. The early phase is computer-assisted; later phases incorporate intellectual input from expert plant and microbial biochemists. The approach thus bridges the gap between automated homology-based annotations and the classical gene discovery efforts of experimentalists, and is much more powerful than purely computational approaches to identifying gene-function associations. Among Arabidopsis genes, we focused on those (2,325 in total) that (i) are unique or belong to families with no more than three members, (ii) are conserved between plants and prokaryotes, and (iii) have unknown or poorly known functions. Computer-assisted selection of promising targets for deeper analysis was based on homology .. independent characteristics associated in the SEED database with the prokaryotic members of each family, specifically gene clustering and phyletic spread, as well as availability of functional genomics data, and publications that could link candidate families to general metabolic areas, or to specific functions. In-depth comparative genomic analysis was then performed for about 500 top candidate families, which connected ~55 of them to general areas of metabolism and led to specific functional predictions for a subset of ~25 more. Twenty predicted functions were experimentally tested in at least one prokaryotic organism

  8. An aerial 3D printing test mission (United States)

    Hirsch, Michael; McGuire, Thomas; Parsons, Michael; Leake, Skye; Straub, Jeremy


    This paper provides an overview of an aerial 3D printing technology, its development and its testing. This technology is potentially useful in its own right. In addition, this work advances the development of a related in-space 3D printing technology. A series of aerial 3D printing test missions, used to test the aerial printing technology, are discussed. Through completing these test missions, the design for an in-space 3D printer may be advanced. The current design for the in-space 3D printer involves focusing thermal energy to heat an extrusion head and allow for the extrusion of molten print material. Plastics can be used as well as composites including metal, allowing for the extrusion of conductive material. A variety of experiments will be used to test this initial 3D printer design. High altitude balloons will be used to test the effects of microgravity on 3D printing, as well as parabolic flight tests. Zero pressure balloons can be used to test the effect of long 3D printing missions subjected to low temperatures. Vacuum chambers will be used to test 3D printing in a vacuum environment. The results will be used to adapt a current prototype of an in-space 3D printer. Then, a small scale prototype can be sent into low-Earth orbit as a 3-U cube satellite. With the ability to 3D print in space demonstrated, future missions can launch production hardware through which the sustainability and durability of structures in space will be greatly improved.

  9. Distributed Multisensor Data Fusion under Unknown Correlation and Data Inconsistency

    Directory of Open Access Journals (Sweden)

    Muhammad Abu Bakr


    Full Text Available The paradigm of multisensor data fusion has been evolved from a centralized architecture to a decentralized or distributed architecture along with the advancement in sensor and communication technologies. These days, distributed state estimation and data fusion has been widely explored in diverse fields of engineering and control due to its superior performance over the centralized one in terms of flexibility, robustness to failure and cost effectiveness in infrastructure and communication. However, distributed multisensor data fusion is not without technical challenges to overcome: namely, dealing with cross-correlation and inconsistency among state estimates and sensor data. In this paper, we review the key theories and methodologies of distributed multisensor data fusion available to date with a specific focus on handling unknown correlation and data inconsistency. We aim at providing readers with a unifying view out of individual theories and methodologies by presenting a formal analysis of their implications. Finally, several directions of future research are highlighted.

  10. Distributed Multisensor Data Fusion under Unknown Correlation and Data Inconsistency. (United States)

    Bakr, Muhammad Abu; Lee, Sukhan


    The paradigm of multisensor data fusion has been evolved from a centralized architecture to a decentralized or distributed architecture along with the advancement in sensor and communication technologies. These days, distributed state estimation and data fusion has been widely explored in diverse fields of engineering and control due to its superior performance over the centralized one in terms of flexibility, robustness to failure and cost effectiveness in infrastructure and communication. However, distributed multisensor data fusion is not without technical challenges to overcome: namely, dealing with cross-correlation and inconsistency among state estimates and sensor data. In this paper, we review the key theories and methodologies of distributed multisensor data fusion available to date with a specific focus on handling unknown correlation and data inconsistency. We aim at providing readers with a unifying view out of individual theories and methodologies by presenting a formal analysis of their implications. Finally, several directions of future research are highlighted.

  11. An Efficient Algorithm for Direction Finding against Unknown Mutual Coupling

    Directory of Open Access Journals (Sweden)

    Weijiang Wang


    Full Text Available In this paper, an algorithm of direction finding is proposed in the presence of unknown mutual coupling. The preliminary direction of arrival (DOA is estimated using the whole array for high resolution. Further refinement can then be conducted by estimating the angularly dependent coefficients (ADCs with the subspace theory. The mutual coupling coefficients are finally determined by solving the least squares problem with all of the ADCs utilized without discarding any. Simulation results show that the proposed method can achieve better performance at a low signal-to-noise ratio (SNR with a small-sized array and is more robust, compared with the similar processes employing the initial DOA estimation and further improvement iteratively.

  12. An efficient algorithm for direction finding against unknown mutual coupling. (United States)

    Wang, Weijiang; Ren, Shiwei; Ding, Yingtao; Wang, Haoyu


    In this paper, an algorithm of direction finding is proposed in the presence of unknown mutual coupling. The preliminary direction of arrival (DOA) is estimated using the whole array for high resolution. Further refinement can then be conducted by estimating the angularly dependent coefficients (ADCs) with the subspace theory. The mutual coupling coefficients are finally determined by solving the least squares problem with all of the ADCs utilized without discarding any. Simulation results show that the proposed method can achieve better performance at a low signal-to-noise ratio (SNR) with a small-sized array and is more robust, compared with the similar processes employing the initial DOA estimation and further improvement iteratively.

  13. Alternate Location Method of a Robot Team in Unknown Environment

    Institute of Scientific and Technical Information of China (English)

    WANG Jian-zhong; LIU Jing-jing


    The alternate location method of a robot team is proposed. Three of the robots are kept still as beacon robots, not always the same ones, while the others are regarded as mobile robots. The mobile robots alternatively measure the distance between one of them and three beacon robots with ultrasonic measurement module. The distance data are combined with its dead-reckoning information using iterated extended Kalman filter(IEKF) to realize the optimal estimate of its position. According to the condition the future beacon robots positions should be desired ones, the target function and the nonlinear constrain equations are set up which are used by nonlinear optimization algorithm to estimate the position of the future beacon robots. By alternately changing the robots roles as active beacon, the alternate location in unknown environment can be realized. Process and result of the simulation test are given and the position estimation error is within±10mm, which proves the validity of this method.

  14. Impact of CT in patients with sepsis of unknown origin

    Energy Technology Data Exchange (ETDEWEB)

    Barkhausen, J.; Stoeblen, F.; Mueller, R.D. [University Hospital Essen (Germany). Dept. of Radiology; Dominguez-Fernandez, E. [University Hospital Essen (Germany). Dept. of General Surgery; Henseke, P. [Nycomed-Amersham Arzneimittel GmbH, Muenchen (Germany)


    Purpose: To evaluate the diagnostic relevance of CT in patients with sepsis of unknown origin. Material and Methods: Sixty-three consecutive intensive care patients with suspicion of an abscess and negative or inconclusive previous radiological examinations were included. CT was performed using the helical technique. A total of 45 abdominal and 38 chest examinations were evaluated. Results: 5/38 examinations of the chest revealed the source of sepsis (pleural empyema 2, lung abscess 1, mediastinitis 1, retrosternal abscess 1). 7/45 abdominal CT examinations showed the source of sepsis (intraabdominal abscess 2, hepatic abscess 3, intestinal perforation 1, gangrenous colitis 1). Conclusion: CT is useful for the evaluation of patients with fever or sepsis without a known source. Due to the detection of a spetic focus by CT, 19% of the patients in our study could be immediately referred to causal therapy as percutaneous drainage or surgery. (orig.)

  15. An active damper to suppress multiple resonances with unknown frequencies

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Blaabjerg, Frede; Liserre, Marco


    The increasing use of power electronics devices tends to aggravate high-frequency harmonics and trigger resonances across a wide frequency range into power systems. This paper presents an active damper to suppress multiple resonances with unknown frequencies. The active damper is realized by a high......-bandwidth power converter that can selectively dampen out the wideband resonances. A cascaded adaptive notch filter structure is proposed to detect the frequencies of resonances, which makes the active damper different from the resistive-active power filter for harmonic resonance suppression. The performance...... of the active damper is validated by implementing it to suppress the resonances in a grid-connected inverter with a long power cable. The results show that the active damper can become a promising approach to stabilizing the future power electronics based power systems....

  16. A Physician’s Nightmare: Fever of Unknown Origin

    Directory of Open Access Journals (Sweden)

    Sana Din


    Full Text Available Fever of unknown origin (FUO remains to be a challenge despite advancement in diagnostic technologies and procedures. FUO is considered when fever presents intermittently without an explanation. It has been linked to various etiologies, which makes it difficult to diagnose. We present the case of 18-month-old female with recurrent fever, splenomegaly, abdominal pain, and constipation. The workup for her symptoms revealed wandering spleen. Wandering spleen is a result from excessive laxity or absence of splenic ligaments. The patient underwent splenectomy and was advised to continue on Senna, Miralax, and high fiber diet. Her mother reported that the fever is no longer present and there is marked improvement in her constipation and abdominal pain after splenectomy.

  17. Villitis of unknown aetiology: correlation of recurrence with clinical outcome.

    LENUS (Irish Health Repository)

    Feeley, L


    Villitis of unknown aetiology (VUA) is associated with adverse pregnancy outcome. Consequently, an ability to predict recurrence could be clinically relevant. We examined placentas where villitis was diagnosed in a previous pregnancy to establish the risk of recurrence and outcome. A total of 304 cases of VUA were diagnosed in our laboratory over a 4-year period. Subsequently, 19 of this cohort had a second placenta examined histologically. Recurrence and clinical outcome were recorded. Villitis recurred in 7 of 19 cases (37%). There was a high level of adverse pregnancy outcome in this cohort overall, characterised by small for gestational age infants and stillbirth, particularly in cases with high-grade villitis. We identified recurrent villitis more frequently than previously reported. Our findings confirm an association between high-grade villitis and poor outcome. Adequately powered prospective studies are required to determine if enhanced surveillance of subsequent pregnancies is indicated following a diagnosis of villitis.

  18. A Brief Introduction on Mystery, the Unknown, Surprise

    Directory of Open Access Journals (Sweden)

    Sean Scanlan


    Full Text Available In this age of globalization, this age of so many ways to know—and so many ways to know things so quickly—it is both satisfying and deeply unnerving to come upon things and events that are really hard to understand, things and events so shocking or strange or mysterious, that they seem Unknown. Perhaps even unknowable. The first note of NANO Issue 2 focuses on an unsolved murder and reveals a mystery that is confounding, creepy, and yet oddly compelling. In “Karr’s Kill Cult: Virtual Cults and Pseudo-Killing in the Digital Age,” Jeremy Biles and Brian Collins explore the edges of where cyber-crime threatens to turn real—and vice versa. In the second note, Jennifer Ballengee compares Oedipus at Colonus with Don DeLillo’s Falling Man.

  19. The Difficulty of Sexing Skeletons from Unknown Populations

    Directory of Open Access Journals (Sweden)

    Ingrid Sierp


    Full Text Available Determination of sex from skeletal remains is performed using a number of methods developed by biological anthropology. They must be evaluated for consistency and for their performance in a forensic setting. Twenty skeletons of varied provenance had their sex determined by 15 existing methods of forensic anthropology (7 metric and 8 morphological. The methods were evaluated for their consistency in determination of sex. No single individual was identified as belonging to one sex exclusively. Ambiguous results were obtained by metric methods for fourteen individuals (70% and by morphological methods for only five individuals (25% (Chi-squared = 4.3, df = 1, P<0.05. Methods which use the size of bones as an indicator of sex perform poorly on skeletal remains of individuals of unknown provenance. Methods which combine morphologic and metric techniques, that is, geometric morphometric analysis, may result in greater levels of consistency.

  20. Modal Parameter Identification from Responses of General Unknown Random Inputs

    DEFF Research Database (Denmark)

    Ibrahim, S. R.; Asmussen, J. C.; Brincker, Rune


    Modal parameter identification from ambient responses due to a general unknown random inputs is investigated. Existing identification techniques which are based on assumptions of white noise and or stationary random inputs are utilized even though the inputs conditions are not satisfied....... This is accomplished via adding. In cascade. A force cascade conversion to the structures system under consideration. The input to the force conversion system is white noise and the output of which is the actual force(s) applied to the structure. The white noise input(s) and the structures responses are then used...... to identify the compined system. Identification results are then sorted as either structural parameters or input force(s) characteristics....

  1. Angiotropic large cell lymphoma presenting as fever of unknown origin. (United States)

    Kuvliev, E; Glamour, T; Shekar, R; West, B C


    Fever has never before been described as the chief complaint and major finding in angiotropic large cell lymphoma (ALCL). ALCL is a rare and usually fatal intravascular tumor characterized by a widespread proliferation of malignant mononuclear cells within vessels of small caliber, causing their blockage. The majority present as high-grade, B-cell lymphomas with a predilection for the central nervous system and the skin. We report a 61-year-old woman who presented with a fever of unknown origin (FUO) that lasted 9 weeks from onset to death. To our knowledge, this is the first case of ALCL to present solely as a FUO, and the second case of ALCL to be diagnosed by muscle biopsy. We suggest that this rare malignancy (ALCL) be considered in the differential diagnosis of FUO.

  2. Obstacle Avoidance for Unmanned Undersea Vehicle in Unknown Unstructured Environment

    Directory of Open Access Journals (Sweden)

    Zheping Yan


    Full Text Available To avoid obstacle in the unknown environment for unmanned undersea vehicle (UUV, an obstacle avoiding system based on improved vector field histogram (VFH is designed. Forward looking sonar is used to detect the environment, and the divisional sonar modal is applied to deal with the measure uncertainty. To adapt to the VFH, rolling occupancy grids are used for the map building, and high accuracy details of local environment are obtained. The threshold is adaptively adjusted by the statistic of obstacles to solve the problem that VFH is sensitive to threshold. To improve the environment adaptability, the hybrid-behaviors strategy is proposed, which selects the optimal avoidance command according to the motion status and environment character. The simulation shows that UUV could avoid the obstacles fast and escape from the U shape obstacles.

  3. Mobile robot navigation in unknown static environments using ANFIS controller

    Directory of Open Access Journals (Sweden)

    Anish Pandey


    Full Text Available Navigation and obstacle avoidance are the most important task for any mobile robots. This article presents the Adaptive Neuro-Fuzzy Inference System (ANFIS controller for mobile robot navigation and obstacle avoidance in the unknown static environments. The different sensors such as ultrasonic range finder sensor and sharp infrared range sensor are used to detect the forward obstacles in the environments. The inputs of the ANFIS controller are obstacle distances obtained from the sensors, and the controller output is a robot steering angle. The primary objective of the present work is to use ANFIS controller to guide the mobile robot in the given environments. Computer simulations are conducted through MATLAB software and implemented in real time by using C/C++ language running Arduino microcontroller based mobile robot. Moreover, the successful experimental results on the actual mobile robot demonstrate the effectiveness and efficiency of the proposed controller.

  4. Blind reconstruction of sparse images with unknown point spread function (United States)

    Herrity, Kyle; Raich, Raviv; Hero, Alfred O., III


    We consider the image reconstruction problem when the original image is assumed to be sparse and when partial knowledge of the point spread function (PSF) is available. In particular, we are interested in recovering the magnetization density given magnetic resonance force microscopy (MRFM) data, and we present an iterative alternating minimization algorithm (AM) to solve this problem. A smoothing penalty is introduced on allowable PSFs to improve the reconstruction. Simulations demonstrate its performance in reconstructing both the image and unknown point spread function. In addition, we develop an optimization transfer approach to solving a total variation (TV) blind deconvolution algorithm presented in a paper by Chan and Wong. We compare the performance of the AM algorithm to the blind TV algorithm as well as to a TV based majorization-minimization algorithm developed by Figueiredo et al.

  5. Cancer of unknown primary origin: a case report

    Directory of Open Access Journals (Sweden)

    Elisa De Carlo


    Full Text Available Carcinoma of unknown primary origin (CUP accounts for 2-10% of all malignancies. The apparent absence of the primary tumour, the development of early, uncommon systemic metastases and the resistance to therapy and poor prognosis are hallmarks of this heterogeneous clinical entity and are a challenge for physicians. The diagnostic workup of patients with CUP includes a large amount of histopathological examination, as well as the use of imaging techniques that often fail to identify the primary tumour. Therefore, the optimal workup and treatment for these patients remains to be determined. Molecular diagnostic tools, such as DNA microarray analysis, could help in the search for "lost" CUP origin and guide the further treatment approach. We report the case of a 66-year-old man, with mediastinal lymph nodes metastasis of carcinoma and neurological syndrome with diplopia and balance disorders, in which many exams have been performed without finding the primary tumour.

  6. Smooth extrapolation of unknown anatomy via statistical shape models (United States)

    Grupp, R. B.; Chiang, H.; Otake, Y.; Murphy, R. J.; Gordon, C. R.; Armand, M.; Taylor, R. H.


    Several methods to perform extrapolation of unknown anatomy were evaluated. The primary application is to enhance surgical procedures that may use partial medical images or medical images of incomplete anatomy. Le Fort-based, face-jaw-teeth transplant is one such procedure. From CT data of 36 skulls and 21 mandibles separate Statistical Shape Models of the anatomical surfaces were created. Using the Statistical Shape Models, incomplete surfaces were projected to obtain complete surface estimates. The surface estimates exhibit non-zero error in regions where the true surface is known; it is desirable to keep the true surface and seamlessly merge the estimated unknown surface. Existing extrapolation techniques produce non-smooth transitions from the true surface to the estimated surface, resulting in additional error and a less aesthetically pleasing result. The three extrapolation techniques evaluated were: copying and pasting of the surface estimate (non-smooth baseline), a feathering between the patient surface and surface estimate, and an estimate generated via a Thin Plate Spline trained from displacements between the surface estimate and corresponding vertices of the known patient surface. Feathering and Thin Plate Spline approaches both yielded smooth transitions. However, feathering corrupted known vertex values. Leave-one-out analyses were conducted, with 5% to 50% of known anatomy removed from the left-out patient and estimated via the proposed approaches. The Thin Plate Spline approach yielded smaller errors than the other two approaches, with an average vertex error improvement of 1.46 mm and 1.38 mm for the skull and mandible respectively, over the baseline approach.

  7. Twelve previously unknown phage genera are ubiquitous in global oceans. (United States)

    Holmfeldt, Karin; Solonenko, Natalie; Shah, Manesh; Corrier, Kristen; Riemann, Lasse; Verberkmoes, Nathan C; Sullivan, Matthew B


    Viruses are fundamental to ecosystems ranging from oceans to humans, yet our ability to study them is bottlenecked by the lack of ecologically relevant isolates, resulting in "unknowns" dominating culture-independent surveys. Here we present genomes from 31 phages infecting multiple strains of the aquatic bacterium Cellulophaga baltica (Bacteroidetes) to provide data for an underrepresented and environmentally abundant bacterial lineage. Comparative genomics delineated 12 phage groups that (i) each represent a new genus, and (ii) represent one novel and four well-known viral families. This diversity contrasts the few well-studied marine phage systems, but parallels the diversity of phages infecting human-associated bacteria. Although all 12 Cellulophaga phages represent new genera, the podoviruses and icosahedral, nontailed ssDNA phages were exceptional, with genomes up to twice as large as those previously observed for each phage type. Structural novelty was also substantial, requiring experimental phage proteomics to identify 83% of the structural proteins. The presence of uncommon nucleotide metabolism genes in four genera likely underscores the importance of scavenging nutrient-rich molecules as previously seen for phages in marine environments. Metagenomic recruitment analyses suggest that these particular Cellulophaga phages are rare and may represent a first glimpse into the phage side of the rare biosphere. However, these analyses also revealed that these phage genera are widespread, occurring in 94% of 137 investigated metagenomes. Together, this diverse and novel collection of phages identifies a small but ubiquitous fraction of unknown marine viral diversity and provides numerous environmentally relevant phage-host systems for experimental hypothesis testing.

  8. Altamira cave Paleolithic paintings harbor partly unknown bacterial communities. (United States)

    Schabereiter-Gurtner, Claudia; Saiz-Jimenez, Cesareo; Piñar, Guadalupe; Lubitz, Werner; Rölleke, Sabine


    Since it has been reported that microorganisms can affect painting pigments, Paleolithic painting microbiology deserves attention. The present study is the first report on the bacterial colonization of the valuable Paleolithic paintings in the famous Altamira cave (Spain). One sample taken from a painting area in the Polychromes Hall was analyzed culture-independently. This was the first time microbiologists were allowed to take sample material directly from Altamira paintings. Identification methods included PCR amplification of 16S rRNA genes (16S rDNA) and community fingerprinting by denaturing gradient gel electrophoresis (DGGE). The applied approach gave insight into a great bacterial taxonomic diversity, and allowed the detection of unexpected and unknown bacteria with potential effects on the conservation of the painting. Regarding the number of 29 visible DGGE bands in the community fingerprint, the numbers of analyzed clones described about 72% of the phylogenetic diversity present in the sample. Thirty-eight percent of the sequences analyzed were phylogenetically most closely related to cultivated bacteria, while the majority (62%) were most closely related to environmental 16S rDNA clones. Bacteria identified in Altamira were related with sequence similarities between 84.8 and 99.4% to members of the cosmopolitan Proteobacteria (52.3%), to members of the Acidobacterium division (23.8%), Cytophaga/Flexibacter/Bacteroides phylum (9.5%), green non-sulfur bacteria (4.8%), Planctomycetales (4.8%) and Actinobacteria (4.8%). The high number of clones most closely related to environmental 16S rDNA clones showed the broad spectrum of unknown and yet to be cultivated bacteria in Altamira cave.

  9. The Science of Mission Assurance

    Directory of Open Access Journals (Sweden)

    Kamal Jabbour


    Full Text Available The intent of this article is to describe—and prescribe—a scientific framework for assuring mission essential functions in a contested cyber environment. Such a framework has profound national security implications as the American military increasingly depends on cyberspace to execute critical mission sets. In setting forth this prescribed course of action, the article will first decompose information systems into atomic processes that manipulate information at all six phases of the information lifecycle, then systematically define the mathematical rules that govern mission assurance.

  10. Letters to the editors. On the subject of the technical note ''irradiation of unknown pregnancy: review of 17 cases - N. Chahed, A. Mhiri, A.; Gaiigi, S.; Mtimet, S.'' published in radioprotection 35 (4), 519-527 (in French); Lettre a la redaction. A propos de la note technique ''irradiation d'une grossesse meconnue: revue a court terme de 17 cas - Chahed, N.; Mhiri, A.; Gaigi, S.; Mtimet, S.'' parue dans radioprotection 35(4), 519-527

    Energy Technology Data Exchange (ETDEWEB)

    Cordoliani, Y.S. [Hopital Val de Grace, Service Radiologique, 75 - Paris (France)


    The I.C.R.P. gives for a malformation risk after irradiation the threshold dose not before 100 m Grays. The radiological examinations that can occur during an unknown pregnancy are broadly smaller than 100 m Grays. It seems that some pregnancy termination have been recommended for examinations with a radiation dose under this threshold. The author recommends to read the document of the French Society of radiology relative to pregnancy and diagnostic irradiation that summarizes the principal situations and the lines to take in the case of an unknown pregnancy irradiation. (N.C.)

  11. 75 FR 6178 - Mission Statement (United States)


    .... companies that are experienced exporters enter Indonesia for the first time in support of creating green... significant resource potential and its desire to invest in cutting-edge clean energy technologies. Mission...

  12. Mission Level Autonomy for USSV (United States)

    Huntsberger, Terry; Stirb, Robert C.; Brizzolara, Robert


    On-water demonstration of a wide range of mission-proven, advanced technologies at TRL 5+ that provide a total integrated, modular approach to effectively address the majority of the key needs for full mission-level autonomous, cross-platform control of USV s. Wide baseline stereo system mounted on the ONR USSV was shown to be an effective sensing modality for tracking of dynamic contacts as a first step to automated retrieval operations. CASPER onboard planner/replanner successfully demonstrated realtime, on-water resource-based analysis for mission-level goal achievement and on-the-fly opportunistic replanning. Full mixed mode autonomy was demonstrated on-water with a seamless transition between operator over-ride and return to current mission plan. Autonomous cooperative operations for fixed asset protection and High Value Unit escort using 2 USVs (AMN1 & 14m RHIB) were demonstrated during Trident Warrior 2010 in JUN 2010

  13. Introduction to mission data system (United States)

    Krasner, S.; Rasmussen, R.


    MDS state-based architecture. A system compromises project assets in the context of some external environments that influences them. The function of mission software is to monitor and control a system to meet operators' intents.

  14. Mission Critical: Preventing Antibiotic Resistance (United States)

    ... this? Submit Button Past Emails Mission Critical: Preventing Antibiotic Resistance Recommend on Facebook Tweet Share Compartir Can you ... spp. So, what can we do to prevent antibiotic resistance in healthcare settings? Patients, healthcare providers, healthcare facility ...

  15. Lunam 2000 (Lunar Atmosphere Mission) (United States)

    Barbieri, Cesare; Fornasier, Sonia; Lazzarin, Monica; Marchi, Simone; Rampazzi, Francesca; Verani, Stefano; Cremonese, Gabriele; Ragazzoni, Roberto; Dolci, Mauro; Benn, Chris R.; Mendillo, Michael; Baumgardner, Jeff; Chakrabarti, Supriya; Wilson, Jody

    LUNAM 2000 is a small mission dedicated to the coronagraphic imaging in the Na yellow doublet and to UV spectroscopy in the range 2800-3400 Å of the lunar atmosphere. These studies are possible only from Space. The scientific return of LUNAM 2000 has a wider appeal for the study of transient atmospheres of other celestial bodies, in particular of Mercury. The mission is in low Earth-orbit (about 350 km); a sun-synchronous or other orbits are under investigation. The payload has very small weight, dimensions and power requests, and is essentially made with off-the-shelf components. It can be built and launched in less than 3 years from the approval. This time frame nicely overlaps that of the European technological Mission SMART 1 and can greatly add to its scientific return. Furthermore, LUNAM 2000 can give very important information to define a mission to Mercury such as Bepi Colombo.

  16. Aeromobile forces in missions abroa

    Directory of Open Access Journals (Sweden)



    Full Text Available This article shows the role of Aeromobile forces during missions abroad. Firstly it will be explained how to understand the concept of “Aeromobile forces”. After that a short classification of missions abroad will be shown. Part I which is the main part of the article will introduce the using of helicopters Mi-17 and Mi-24 through the example from three different missions in Ethiopia, Chad and Afghanistan by showing their main tasks. Analysis included in this article should help with estimating capability of old types of helicopters. This chapter will raise an issue concern method for dealing with resistance. Last part will involve some costs explanation connected to helicopter operating costs. The conclusions contain the lessons learned from all missions mentioned in the article and some prospective possible solutions.

  17. Mission Readiness Measurement Aid (MIRMAID)

    National Research Council Canada - National Science Library

    Bowden, Tim


    .... The tool we have designed is intended to combine automated and observed measures of performance to provide the Commanding Officer feedback regarding the readiness of his unit to perform key missions...

  18. General Mission Analysis Tool (GMAT) (United States)

    Hughes, Steven P. (Compiler)


    This is a software tutorial and presentation demonstrating the application of the General Mission Analysis Tool (GMAT) to the critical design phase of NASA missions. The demonstration discusses GMAT basics, then presents a detailed example of GMAT application to the Transiting Exoplanet Survey Satellite (TESS) mission. Other examples include OSIRIS-Rex. This talk is a combination of existing presentations; a GMAT basics and overview, and technical presentations from the TESS and OSIRIS-REx projects on their application of GMAT to critical mission design. The GMAT basics slides are taken from the open source training material. The OSIRIS-REx slides are from a previous conference presentation. The TESS slides are a streamlined version of the CDR package provided by the project with SBU and ITAR data removed by the TESS project.

  19. Starshade Rendezvous Mission Probe Concept (United States)

    Seager, Sara; Kasdin, Jeremy; Starshade Rendezvous Probe Team


    The Starshade Rendezvous Mission Concept Prove is a Starshade that works with the WFIRST Mission, but is built and launched separately, with a rendezvous on orbit. A 2015 Exo-S report first detailed the mission concept. In the current study we develop a new scientific vision for WFIRST exoplanet discovery and characterization, using the complementary coronagraph and starshade to execute the most sensitive and thorough direct imaging campaign ever attempted. The overarching goal of our proposal is to carry out the first “deep dive” direct imaging exploration of planetary systems orbiting the nearest sun-like stars in a search for Earth-like planets using only a fraction of the WFIRST telescope time. The study aims to improve on the Exo-S 2015 report with updated study of the key spacecraft and starshade technology development issues, as related to WFIRST design changes since 2015 that make the timely implementation of such a mission possible.

  20. Requirements for Common Bomber Mission Planning Environment

    National Research Council Canada - National Science Library

    White, III, Samuel G


    ...) level mission planning as a whole. Unfortunately, many of these initiatives have fallen short of seamlessly connecting the tactical level mission planning processes with the operational level or providing the unit-level mission...

  1. General Mission Analysis Tool (GMAT) Mathematical Specifications (United States)

    Hughes, Steve


    The General Mission Analysis Tool (GMAT) is a space trajectory optimization and mission analysis system developed by NASA and private industry in the spirit of the NASA Mission. GMAT contains new technology and is a testbed for future technology development.

  2. EOS Terra: Mission Status Constellation MOWG (United States)

    Mantziaras, Dimitrios


    This EOS Terra Mission Status Constellation MOWG will discuss mission summary; spacecraft subsystems summary, recent and planned activities; inclination adjust maneuvers, conjunction history, propellant usage and lifetime estimate; and end of mission plan.

  3. Physiological and psychological stress limits for astronautics Observations during the Skylab I-III missions (United States)

    Burchard, E. C.


    The physiological and psychological factors of manned space flight had a particular significance in the Skylab missions during which astronauts were subjected to a life in a space environment for longer periods of time than on previous space missions. The Skylab missions demonstrated again the great adaptability of human physiology to the environment of man. The results of Skylab have indicated also approaches for enhancing the capability of man to tolerate the physiological and psychological stresses of space flight.

  4. Overview of the Gaia Mission (United States)

    Perryman, M. A. C.


    The overall goals and organisation of the Gaia mission are described: the role of the scientific community in the project; the organisation, structure, and goals of the scientific working groups; their interaction and influence on the satellite and payload design; the overall project schedule; the organisation and overall approach to the challenges of the data analysis; and the mission data products and their estimated release dates. Some of the potential for education and outreach activities are noted.

  5. Urinary albumin in space missions

    DEFF Research Database (Denmark)

    Cirillo, Massimo; De Santo, Natale G; Heer, Martina


    Proteinuria was hypothesized for space mission but research data are missing. Urinary albumin, as index of proteinuria, was analyzed in frozen urine samples collected by astronauts during space missions onboard MIR station and on ground (control). Urinary albumin was measured by a double antibody...... radioimmunoassay. On average, 24h urinary albumin was 27.4% lower in space than on ground; the difference was statistically significant. Low urinary albumin excretion could be another effect of exposure to weightlessness (microgravity)....

  6. Communication to within a fidelity criterion over unknown networks by reduction to reliable communication problems over unknown networks

    CERN Document Server

    Agarwal, Mukul


    Consider a scenerio where various users want to communicate with each other over an unknown network to within a fidelity criterion. Thus, there are various users. Each user has a source that it wants to send to another user to within some distortion level. We abstract this problem as that of universal communication of random sources over networks to within a distortion criterion. We compute ta universally reliably achievable region for a set of networks where networks in the set are defined in terms of end to end distortion that they achieve for transmission of independent signals between various nodes assuming that there is common randomness between sender and corresponding receiver. Using this, we provide results for when communication of independent signals to within particular fidelity criteria is possible in terms of when reliable communication is possible. Using this, we show that when the sources at the various nodes are independent of each other, it is sufficient to consider separation architectures: ...

  7. Social Tagging of Mission Data (United States)

    Norris, Jeffrey S.; Wallick, Michael N.; Joswig, Joseph C.; Powell, Mark W.; Torres, Recaredo J.; Mittman, David S.; Abramyan, Lucy; Crockett, Thomas M.; Shams, Khawaja S.; Fox, Jason M.; hide


    Mars missions will generate a large amount of data in various forms, such as daily plans, images, and scientific information. Often, there is a semantic linkage between images that cannot be captured automatically. Software is needed that will provide a method for creating arbitrary tags for this mission data so that items with a similar tag can be related to each other. The tags should be visible and searchable for all users. A new routine was written to offer a new and more flexible search option over previous applications. This software allows users of the MSLICE program to apply any number of arbitrary tags to a piece of mission data through a MSLICE search interface. The application of tags creates relationships between data that did not previously exist. These tags can be easily removed and changed, and contain enough flexibility to be specifically configured for any mission. This gives users the ability to quickly recall or draw attention to particular pieces of mission data, for example: Give a semantic and meaningful description to mission data; for example, tag all images with a rock in them with the tag "rock." Rapidly recall specific and useful pieces of data; for example, tag a plan as"driving template." Call specific data to a user s attention; for example, tag a plan as "for:User." This software is part of the MSLICE release, which was written in Java. It will run on any current Windows, Macintosh, or Linux system.

  8. Kriging with Unknown Variance Components for Regional Ionospheric Reconstruction

    Directory of Open Access Journals (Sweden)

    Ling Huang


    Full Text Available Ionospheric delay effect is a critical issue that limits the accuracy of precise Global Navigation Satellite System (GNSS positioning and navigation for single-frequency users, especially in mid- and low-latitude regions where variations in the ionosphere are larger. Kriging spatial interpolation techniques have been recently introduced to model the spatial correlation and variability of ionosphere, which intrinsically assume that the ionosphere field is stochastically stationary but does not take the random observational errors into account. In this paper, by treating the spatial statistical information on ionosphere as prior knowledge and based on Total Electron Content (TEC semivariogram analysis, we use Kriging techniques to spatially interpolate TEC values. By assuming that the stochastic models of both the ionospheric signals and measurement errors are only known up to some unknown factors, we propose a new Kriging spatial interpolation method with unknown variance components for both the signals of ionosphere and TEC measurements. Variance component estimation has been integrated with Kriging to reconstruct regional ionospheric delays. The method has been applied to data from the Crustal Movement Observation Network of China (CMONOC and compared with the ordinary Kriging and polynomial interpolations with spherical cap harmonic functions, polynomial functions and low-degree spherical harmonic functions. The statistics of results indicate that the daily ionospheric variations during the experimental period characterized by the proposed approach have good agreement with the other methods, ranging from 10 to 80 TEC Unit (TECU, 1 TECU = 1 × 1016 electrons/m2 with an overall mean of 28.2 TECU. The proposed method can produce more appropriate estimations whose general TEC level is as smooth as the ordinary Kriging but with a smaller standard deviation around 3 TECU than others. The residual results show that the interpolation precision of the

  9. Random neural Q-learning for obstacle avoidance of a mobile robot in unknown environments

    Directory of Open Access Journals (Sweden)

    Jing Yang


    Full Text Available The article presents a random neural Q-learning strategy for the obstacle avoidance problem of an autonomous mobile robot in unknown environments. In the proposed strategy, two independent modules, namely, avoidance without considering the target and goal-seeking without considering obstacles, are first trained using the proposed random neural Q-learning algorithm to obtain their best control policies. Then, the two trained modules are combined based on a switching function to realize the obstacle avoidance in unknown environments. For the proposed random neural Q-learning algorithm, a single-hidden layer feedforward network is used to approximate the Q-function to estimate the Q-value. The parameters of the single-hidden layer feedforward network are modified using the recently proposed neural algorithm named the online sequential version of extreme learning machine, where the parameters of the hidden nodes are assigned randomly and the sample data can come one by one. However, different from the original online sequential version of extreme learning machine algorithm, the initial output weights are estimated subjected to quadratic inequality constraint to improve the convergence speed. Finally, the simulation results demonstrate that the proposed random neural Q-learning strategy can successfully solve the obstacle avoidance problem. Also, the higher learning efficiency and better generalization ability are achieved by the proposed random neural Q-learning algorithm compared with the Q-learning based on the back-propagation method.

  10. Effects of Memory Colour on Colour Constancy for Unknown Coloured Objects

    Directory of Open Access Journals (Sweden)

    Jeroen J M Granzier


    Full Text Available The perception of an object's colour remains constant despite large variations in the chromaticity of the illumination—colour constancy. Hering suggested that memory colours, the typical colours of objects, could help in estimating the illuminant's colour and therefore be an important factor in establishing colour constancy. Here we test whether the presence of objects with diagnostical colours (fruits, vegetables, etc within a scene influence colour constancy for unknown coloured objects in the scene. Subjects matched one of four Munsell papers placed in a scene illuminated under either a reddish or a greenish lamp with the Munsell book of colour illuminated by a neutral lamp. The Munsell papers were embedded in four different scenes—one scene containing diagnostically coloured objects, one scene containing incongruent coloured objects, a third scene with geometrical objects of the same colour as the diagnostically coloured objects, and one scene containing non-diagnostically coloured objects (eg, a yellow coffee mug. All objects were placed against a black background. Colour constancy was on average significantly higher for the scene containing the diagnostically coloured objects compared with the other scenes tested. We conclude that the colours of familiar objects help in obtaining colour constancy for unknown objects.

  11. Effects of memory colour on colour constancy for unknown coloured objects. (United States)

    Granzier, Jeroen J M; Gegenfurtner, Karl R


    The perception of an object's colour remains constant despite large variations in the chromaticity of the illumination-colour constancy. Hering suggested that memory colours, the typical colours of objects, could help in estimating the illuminant's colour and therefore be an important factor in establishing colour constancy. Here we test whether the presence of objects with diagnostical colours (fruits, vegetables, etc) within a scene influence colour constancy for unknown coloured objects in the scene. Subjects matched one of four Munsell papers placed in a scene illuminated under either a reddish or a greenish lamp with the Munsell book of colour illuminated by a neutral lamp. The Munsell papers were embedded in four different scenes-one scene containing diagnostically coloured objects, one scene containing incongruent coloured objects, a third scene with geometrical objects of the same colour as the diagnostically coloured objects, and one scene containing non-diagnostically coloured objects (eg, a yellow coffee mug). All objects were placed against a black background. Colour constancy was on average significantly higher for the scene containing the diagnostically coloured objects compared with the other scenes tested. We conclude that the colours of familiar objects help in obtaining colour constancy for unknown objects.

  12. Effects of memory colour on colour constancy for unknown coloured objects (United States)

    Granzier, Jeroen J M; Gegenfurtner, Karl R


    The perception of an object's colour remains constant despite large variations in the chromaticity of the illumination—colour constancy. Hering suggested that memory colours, the typical colours of objects, could help in estimating the illuminant's colour and therefore be an important factor in establishing colour constancy. Here we test whether the presence of objects with diagnostical colours (fruits, vegetables, etc) within a scene influence colour constancy for unknown coloured objects in the scene. Subjects matched one of four Munsell papers placed in a scene illuminated under either a reddish or a greenish lamp with the Munsell book of colour illuminated by a neutral lamp. The Munsell papers were embedded in four different scenes—one scene containing diagnostically coloured objects, one scene containing incongruent coloured objects, a third scene with geometrical objects of the same colour as the diagnostically coloured objects, and one scene containing non-diagnostically coloured objects (eg, a yellow coffee mug). All objects were placed against a black background. Colour constancy was on average significantly higher for the scene containing the diagnostically coloured objects compared with the other scenes tested. We conclude that the colours of familiar objects help in obtaining colour constancy for unknown objects. PMID:23145282

  13. Sensibility and Subjectivity: Levinas’ Traumatic Subject

    Directory of Open Access Journals (Sweden)

    Rashmika Pandya


    Full Text Available The importance of Levinas’ notions of sensibility and subjectivity are evident in the revision of phenomenological method by current phenomenologists such as Jean-Luc Marion and Michel Henry. The criticisms of key tenants of classical phenomenology, intentionality and reduction, are of a particular note. However, there are problems with Levinas’ characterization of subjectivity as essentially sensible. In “Totality and Infinity” and “Otherwise than Being”, Levinas criticizes and recasts a traditional notion of subjectivity, particularly the notion of the subject as the first and foremost rational subject. The subject in Levinas’ works is characterized more by its sensibility and affectedness than by its capacity to reason or affect its world. Levinas ties rationality to economy and suggests an alternative notion of reason that leads to his analysis of the ethical relation as the face-to-face encounter. The ‘origin’ of the social relation is located not in our capacity to know but rather in a sensibility that is diametrically opposed to the reason understood as economy. I argue that the opposition in Levinas’ thought between reason and sensibility is problematic and essentially leads to a self-conflicted subject. In fact, it would seem that violence characterizes the subject’s self-relation and, thus, is also inscribed at the base of the social relation. Rather than overcoming a problematic tendency to dualistic thought in philosophy Levinas merely reverses traditional hierarchies of reason/emotion, subject/object and self/other. 

  14. Territory: An Unknown Quantity in Debates on Territorial Cohesion

    Directory of Open Access Journals (Sweden)

    Andreas Faludi


    Full Text Available There are complaints about territorial cohesion being a vague concept, but in relevant debates territory, too, figures as an unknown quantity. Thus, is it the fixed property of any state, region or local administrative unit, or is it a malleable social construct; rather than being filled with bounded territories, does space overall contain a dynamic network with fuzzy internal, as well as external boundaries, with implications for territorial cohesion? After all, if the former were to be true, territorial cohesion would refer to qualities of what is inside bounded territories. If it were to be the latter, then the meaning of territorial cohesion would include qualities of the relations within a complex network of socially constructed, sometimes ephemeral constructs. There are implications for the ways subsidiarity and multi-level governance are invoked in EU discourse where there is a similar failure to question the underlying notion of territory. What is relevant here is the distinction between a ‘territorial’ and ‘relational’ geography. Considered opinion suggests that these alternatives can and, in view of the persistence of the principle of territorial representation, must be reconciled. However, though firmly entrenched, some constitutional theorists question the very principle. The debate is far from conclusive but at least it shows that discussion, even of this apparently fundamental principle is possible.

  15. Physics at 13 TeV: CMS - scanning the unknown

    CERN Multimedia

    Antonella Del Rosso


    CMS is getting ready to use its accurate detector to scan the many ripples of the unknown physics that may lie beyond the Standard Model. Foremost in everyone’s mind is the search for signs of the production of dark matter at a man-made machine.   Interestingly, the observation of dark matter or new weakly interacting particles implies detecting that some energy has escaped, i.e. it’s missing from the upcoming proton collisions at the LHC. This is why measuring and understanding “missing energy” will be a very important step in that direction. “A large amount of missing energy is the signature for many processes of physics beyond the Standard Model. However, it’s not the only interesting signature that we will be able to exploit when the new collision energy is available,” explains Luca Malgeri, CMS Physics Coordinator. Among the interesting things not associated with missing energy are high-mass resonanc...

  16. [Tilt test for the evaluation of syncope of unknown origin]. (United States)

    Muratore, C; Rabinovich, R; Valentino, M; Baranchuk, A; Liprandi, A S


    The aim of this study was to evaluate the usefulness of head up tilt testing in patients with syncope of unknown origin. Between January 1994 and September 1995, 93 patients were referred for tilt table assessment due to recurrent syncope of uncertain etiology. There were 42 men (mean age 59 years). Thirty healthy volunteers served as a control group. The specific protocol used involved an initial period of supine rest for 15'. Baseline blood pressure (BP) and heart rate (HR) were recorded. This was followed by a tilt to 80 degrees for 30', BP and HR were measured every minute during the procedure. The test was considered positive when symptoms appeared associated with one of the following responses: systolic BP decreased more than 30 mmHg (vasodepressor), bradicardia or asystolia for up to 3" (cardioinhibitory) or mixed. The tilt test was positive in 31 of 93 patients (33%). Seventeen patients (55%) had a vasodepressor response, 3 patients (9%) a cardioinhibitory response and 11 patients (36%) mixed responses. The clinical manifestations were 62% near syncope, 19% syncope and the other patients presented dypsnea or dizziness. The symptoms disappeared promptly after adopting the supine position. None of the 30 healthy volunteers developed symptoms. We conclude that head up tilt test is a safe and effective method for identifying a neurocardiogenic origin in a syncope of uncertain etiology.

  17. Gravity, strings and particles a journey into the unknown

    CERN Document Server

    Gasperini, Maurizio


    New fundamental forces of Nature? New forms of "dark'' energy? Signals from epochs preceding the Big Bang? Is our space-time unique? Only a joint study of the three topics examined in this book – gravity, strings and particles – may provide answers to these questions. Such a study may also provide the key to solving one of the most fascinating mysteries of modern science, namely: Besides time and the three spatial dimensions, how many other dimensions exist in our universe? The book is primarily addressed to readers who do not necessarily have a specific background in physics but are nevertheless interested in discovering the originality and the possible implications of some of the amazing ideas in modern theoretical physics. The emphasis is on conveying ideas rather than explaining formulas, focusing not on what is known but -- mainly -- on what is still unknown. Many parts of the book are devoted to fundamental theoretical models and results which are potentially highly relevant for a deeper understand...

  18. Chronic kidney disease of unknown etiology in Sri Lanka. (United States)

    Rajapakse, Senaka; Shivanthan, Mitrakrishnan Chrishan; Selvarajah, Mathu


    In the last two decades, chronic kidney disease of unknown etiology (CKDu) has emerged as a significant contributor to the burden of chronic kidney disease (CKD) in rural Sri Lanka. It is characterized by the absence of identified causes for CKD. The prevalence of CKDu is 15.1-22.9% in some Sri Lankan districts, and previous research has found an association with farming occupations. A systematic literature review in Pubmed, Embase, Scopus, and Lilacs databases identified 46 eligible peer-reviewed articles and one conference abstract. Geographical mapping indicates a relationship between CKDu and agricultural irrigation water sources. Health mapping studies, human biological studies, and environment-based studies have explored possible causative agents. Most studies focused on likely causative agents related to agricultural practices, geographical distribution based on the prevalence and incidence of CKDu, and contaminants identified in drinking water. Nonetheless, the link between agrochemicals or heavy metals and CKDu remains to be established. No definitive cause for CKDu has been identified. Evidence to date suggests that the disease is related to one or more environmental agents, however pinpointing a definite cause for CKDu is challenging. It is plausible that CKDu is multifactorial. No specific guidelines or recommendations exist for treatment of CKDu, and standard management protocols for CKD apply. Changes in agricultural practices, provision of safe drinking water, and occupational safety precautions are recommended by the World Health Organization.

  19. Adaptive stochastic resonance for unknown and variable input signals. (United States)

    Krauss, Patrick; Metzner, Claus; Schilling, Achim; Schütz, Christian; Tziridis, Konstantin; Fabry, Ben; Schulze, Holger


    All sensors have a threshold, defined by the smallest signal amplitude that can be detected. The detection of sub-threshold signals, however, is possible by using the principle of stochastic resonance, where noise is added to the input signal so that it randomly exceeds the sensor threshold. The choice of an optimal noise level that maximizes the mutual information between sensor input and output, however, requires knowledge of the input signal, which is not available in most practical applications. Here we demonstrate that the autocorrelation of the sensor output alone is sufficient to find this optimal noise level. Furthermore, we demonstrate numerically and analytically the equivalence of the traditional mutual information approach and our autocorrelation approach for a range of model systems. We furthermore show how the level of added noise can be continuously adapted even to highly variable, unknown input signals via a feedback loop. Finally, we present evidence that adaptive stochastic resonance based on the autocorrelation of the sensor output may be a fundamental principle in neuronal systems.

  20. Fever of unknown origin: subacute thyroiditis versus typhoid fever. (United States)

    Cunha, Burke A; Thermidor, Marjorie; Mohan, Sowjanya; Valsamis, Ageliki S; Johnson, Diane H


    Fever of unknown origin (FUO) is not infrequently a diagnostic dilemma for clinicians. Common infectious causes include endocarditis and abscesses in adults, and noninfectious causes include neoplasms and certain collagen vascular diseases, for example, polymyalgia rheumatica, various vasculitides, and juvenile rheumatoid arthritis (adult Still's disease). Subacute thyroiditis is a rare cause of FUO. Among the infectious causes of FUO, typhoid fever is relatively uncommon. We present a case of FUO in a traveler returning from India whose initial complaints were that of left-sided neck pain and angle of the jaw pain, which initially suggested the diagnosis of subacute thyroiditis. After an extensive FUO workup, when typhoid fever is a likely diagnostic possibility, an empiric trial of anti- Salmonella therapy has diagnostic and therapeutic significance. The presence of relative bradycardia, and response to quinolone therapy, was the basis of the clinical diagnosis of typhoid fever as the explanation for this patients FUO. This case illustrates the diagnostic difficulties in assessing patients with FUO with few diagnostic findings.

  1. Fever of unknown origin responding to steroid therapy. (United States)

    Suzuki, A; Ohosone, Y; Mita, S; Obana, M; Matsuoka, Y; Irimajiri, S


    It is not uncommon to find cases of fever of unknown origin (FUO) in which no final diagnosis is made ever after various examinations. We investigated such cases of undiagnosed FUO, with fever persisting for a long periods and responding to steroid therapy. Among 4,596 patients who were hospitalized over 3-year period from September 1991, 25 met Petersdorf's definition of FUO. Among these 25 patient, six cases were steroid-responsive undiagnosed FUO (SR-FUO). Patients with SR-FUO had the following characteristics: marked inflammatory findings and severe illness; without a definite underlying disease being found despite various examinations; no findings which indicated any known diseases such as adult-onset Still's disease, polymyalgia rheumatica, or other collagen diseases; elderly onset, at 58 to 77 years of age (mean age: 67 years); no improvement with antibiotics, antituberculous agents, or antimycotic drugs; significant improvement of symptoms and signs with steroid therapy; and a relatively good prognosis. SR-FUO, which is not caused by any known disease and is highly responsive to steroids, is included among the FUO cases which we have difficulty in diagnosing and treating.

  2. Kidnapping Detection and Recognition in Previous Unknown Environment

    Directory of Open Access Journals (Sweden)

    Yang Tian


    Full Text Available An unaware event referred to as kidnapping makes the estimation result of localization incorrect. In a previous unknown environment, incorrect localization result causes incorrect mapping result in Simultaneous Localization and Mapping (SLAM by kidnapping. In this situation, the explored area and unexplored area are divided to make the kidnapping recovery difficult. To provide sufficient information on kidnapping, a framework to judge whether kidnapping has occurred and to identify the type of kidnapping with filter-based SLAM is proposed. The framework is called double kidnapping detection and recognition (DKDR by performing two checks before and after the “update” process with different metrics in real time. To explain one of the principles of DKDR, we describe a property of filter-based SLAM that corrects the mapping result of the environment using the current observations after the “update” process. Two classical filter-based SLAM algorithms, Extend Kalman Filter (EKF SLAM and Particle Filter (PF SLAM, are modified to show that DKDR can be simply and widely applied in existing filter-based SLAM algorithms. Furthermore, a technique to determine the adapted thresholds of metrics in real time without previous data is presented. Both simulated and experimental results demonstrate the validity and accuracy of the proposed method.

  3. Crowdsourcing the unknown: the satellite search for Genghis Khan.

    Directory of Open Access Journals (Sweden)

    A Y M Lin

    Full Text Available Massively parallel collaboration and emergent knowledge generation is described through a large scale survey for archaeological anomalies within ultra-high resolution earth-sensing satellite imagery. Over 10K online volunteers contributed 30K hours (3.4 years, examined 6,000 km², and generated 2.3 million feature categorizations. Motivated by the search for Genghis Khan's tomb, participants were tasked with finding an archaeological enigma that lacks any historical description of its potential visual appearance. Without a pre-existing reference for validation we turn towards consensus, defined by kernel density estimation, to pool human perception for "out of the ordinary" features across a vast landscape. This consensus served as the training mechanism within a self-evolving feedback loop between a participant and the crowd, essential driving a collective reasoning engine for anomaly detection. The resulting map led a National Geographic expedition to confirm 55 archaeological sites across a vast landscape. A increased ground-truthed accuracy was observed in those participants exposed to the peer feedback loop over those whom worked in isolation, suggesting collective reasoning can emerge within networked groups to outperform the aggregate independent ability of individuals to define the unknown.

  4. Ultrastructural mitochondrial alterations in equine myopathies of unknown origin. (United States)

    Van Driessche, K; Ducatelle, R; Chiers, K; Van Coster, R; van der Kolk, J H; van der Kolk, H


    Very few mitochondrial myopathies have been described in horses. To examine the ultrastructure of muscle mitochondria in equine cases of myopathy of unknown origin. Biopsies of vastus lateralis of the Musculus quadriceps femoris were taken predominantly immediately post mortem and processed for transmission electron microscopy. As a result, electron micrographs of 90 horses in total were available for analysis comprising 4 control horses, 16 horses suffering from myopathy and 70 otherwise diseased horses. Following a thorough clinical and laboratory work-up, four out of five patients that did not fit into the usual algorithm to detect known causes of myopathy showed ultrastructural mitochondrial alterations. Small mitochondria with zones with complete disruption of cristae associated with lactic acidemia were detected in a 17-year-old pony mare, extremely long and slender mitochondria with longitudinal cristae in a 5-year-old Quarter horse stallion, a mixture of irregular extremely large mitochondria (measuring 2500 by 800 nm) next to smaller ones in an 8-year-old Hanoverian mare and round mitochondria with only few cristae in a 11-year-old pony gelding. It remains uncertain whether the subsarcolemmal mitochondrial accumulations observed in the fifth patient have any pathological significance. Ultrastructural alterations in mitochondria were detected in at least four horses. To conclude that these are due to mitochondrial dysfuntions, biochemical tests should be performed. The possibility of a mitochondrial myopathy should be included in the differential diagnosis of muscle weakness.

  5. Anaerobic oxidation of methane: progress with an unknown process. (United States)

    Knittel, Katrin; Boetius, Antje


    Methane is the most abundant hydrocarbon in the atmosphere, and it is an important greenhouse gas, which has so far contributed an estimated 20% of postindustrial global warming. A great deal of biogeochemical research has focused on the causes and effects of the variation in global fluxes of methane throughout earth's history, but the underlying microbial processes and their key agents remain poorly understood. This is a disturbing knowledge gap because 85% of the annual global methane production and about 60% of its consumption are based on microbial processes. Only three key functional groups of microorganisms of limited diversity regulate the fluxes of methane on earth, namely the aerobic methanotrophic bacteria, the methanogenic archaea, and their close relatives, the anaerobic methanotrophic archaea (ANME). The ANME represent special lines of descent within the Euryarchaeota and appear to gain energy exclusively from the anaerobic oxidation of methane (AOM), with sulfate as the final electron acceptor according to the net reaction: CH(4) + SO(42-) ---> HCO(3-) + HS(-) + H(2)O. This review summarizes what is known and unknown about AOM on earth and its key catalysts, the ANME clades and their bacterial partners.

  6. Challenges of the Unknown: Clinical Application of Microbial Metagenomics

    Directory of Open Access Journals (Sweden)

    Graham Rose


    Full Text Available Availability of fast, high throughput and low cost whole genome sequencing holds great promise within public health microbiology, with applications ranging from outbreak detection and tracking transmission events to understanding the role played by microbial communities in health and disease. Within clinical metagenomics, identifying microorganisms from a complex and host enriched background remains a central computational challenge. As proof of principle, we sequenced two metagenomic samples, a known viral mixture of 25 human pathogens and an unknown complex biological model using benchtop technology. The datasets were then analysed using a bioinformatic pipeline developed around recent fast classification methods. A targeted approach was able to detect 20 of the viruses against a background of host contamination from multiple sources and bacterial contamination. An alternative untargeted identification method was highly correlated with these classifications, and over 1,600 species were identified when applied to the complex biological model, including several species captured at over 50% genome coverage. In summary, this study demonstrates the great potential of applying metagenomics within the clinical laboratory setting and that this can be achieved using infrastructure available to nondedicated sequencing centres.

  7. Navy-NGO Coordination for Health-Related HCA Missions: A Suggested Planning Framework (United States)


    tooth extractions, fillings, sealants, and fluoride applications • Pediatric checkups and basic medical evaluations 12 For more information about...based HRHCA missions. 15. SUBJECT TERMS BUMED, NGO, Coordination, HCA, Humanitarian, Civic Assistance, Hospital Ship, Medical , Barriers 16...Humanitarian and civic assistance (HCA) missions are military mis- sions that deliver medical , dental, and other services to underserved populations

  8. The Asteroid Redirect Mission (ARM) (United States)

    Abell, Paul; Gates, Michele; Johnson, Lindley; Chodas, Paul; Mazanek, Dan; Reeves, David; Ticker, Ronald


    To achieve its long-term goal of sending humans to Mars, the National Aeronautics and Space Administration (NASA) plans to proceed in a series of incrementally more complex human spaceflight missions. Today, human flight experience extends only to Low-Earth Orbit (LEO), and should problems arise during a mission, the crew can return to Earth in a matter of minutes to hours. The next logical step for human spaceflight is to gain flight experience in the vicinity of the Moon. These cis-lunar missions provide a "proving ground" for the testing of systems and operations while still accommodating an emergency return path to the Earth that would last only several days. Cis-lunar mission experience will be essential for more ambitious human missions beyond the Earth-Moon system, which will require weeks, months, or even years of transit time. In addition, NASA has been given a Grand Challenge to find all asteroid threats to human populations and know what to do about them. Obtaining knowledge of asteroid physical properties combined with performing technology demonstrations for planetary defense provide much needed information to address the issue of future asteroid impacts on Earth. Hence the combined objectives of human exploration and planetary defense give a rationale for the Asteroid Re-direct Mission (ARM). Mission Description: NASA's ARM consists of two mission segments: 1) the Asteroid Redirect Robotic Mission (ARRM), the first robotic mission to visit a large (greater than ~100 m diameter) near-Earth asteroid (NEA), collect a multi-ton boulder from its surface along with regolith samples, demonstrate a planetary defense technique, and return the asteroidal material to a stable orbit around the Moon; and 2) the Asteroid Redirect Crewed Mission (ARCM), in which astronauts will take the Orion capsule to rendezvous and dock with the robotic vehicle, conduct multiple extravehicular activities to explore the boulder, and return to Earth with samples. NASA's proposed

  9. A mission planning concept and mission planning system for future manned space missions (United States)

    Wickler, Martin


    The international character of future manned space missions will compel the involvement of several international space agencies in mission planning tasks. Additionally, the community of users requires a higher degree of freedom for experiment planning. Both of these problems can be solved by a decentralized mission planning concept using the so-called 'envelope method,' by which resources are allocated to users by distributing resource profiles ('envelopes') which define resource availabilities at specified times. The users are essentially free to plan their activities independently of each other, provided that they stay within their envelopes. The new developments were aimed at refining the existing vague envelope concept into a practical method for decentralized planning. Selected critical functions were exercised by planning an example, founded on experience acquired by the MSCC during the Spacelab missions D-1 and D-2. The main activity regarding future mission planning tasks was to improve the existing MSCC mission planning system, using new techniques. An electronic interface was developed to collect all formalized user inputs more effectively, along with an 'envelope generator' for generation and manipulation of the resource envelopes. The existing scheduler and its data base were successfully replaced by an artificial intelligence scheduler. This scheduler is not only capable of handling resource envelopes, but also uses a new technology based on neuronal networks. Therefore, it is very well suited to solve the future scheduling problems more efficiently. This prototype mission planning system was used to gain new practical experience with decentralized mission planning, using the envelope method. In future steps, software tools will be optimized, and all data management planning activities will be embedded into the scheduler.

  10. Human interactions during Shuttle/Mir space missions (United States)

    Kanas, Nick; Salnitskiy, Vyacheslav; Grund, Ellen M.; Weiss, Daniel S.; Gushin, Vadim; Kozerenko, Olga; Sled, Alexander; Marmar, Charles R.


    To improve the interpersonal climate of crewmembers involved with long-duration space missions, it is important to understand the factors affecting their interactions with each other and with members of mission control. This paper will present findings from a recently completed NASA-funded study during the Shuttle/Mir program which evaluated in-group/out-group displacement of negative emotions; changes in tension, cohesion, and leader support over time; and cultural differences. In-flight data were collected from 5 astronauts, 8 cosmonauts, and 42 American and 16 Russian mission control personnel who signed informed consent. Subjects completed a weekly questionnaire that assessed their mood and perception of their work group's interpersonal climate using questions from well-known, standardized measures (Profile of Mood States, Group and Work Environment Scales) and a critical incident log. There was strong evidence for the displacement of tension and dysphoric emotions from crewmembers to mission control personnel and from mission control personnel to management. There was a perceived decrease in commander support during the 2 nd half of the missions, and for American crewmembers a novelty effect was found on several subscales during the first few months on-orbit. There were a number of differences between American and Russian responses which suggested that the former were less happy with their interpersonal environment than the latter. Mission control personnel reported more tension and dysphoria than crewmembers, although both groups scored better than other work groups on Earth. Nearly all reported critical incidents came from ground subjects, with Americans and Russians showing important differences in response frequencies.

  11. Mission and system concepts for Mars robotic precursor missions (United States)

    Scoon, George E. N.; Hechler, Martin


    Mission and system design concepts reflecting the status at about the midpoint of the Marsnet phase A study are reported. The objective of Marsnet is to place three to four small stations (approximately 80 kg) on the surface of Mars to perform scientific measurements in the areas of geophysics (seismology), geology, geochemistry, mineralogy, meteorology, and exobiology. The ESA Landers will constitute part of a global network to which NASA is planning to contribute up to 16 other stations. The Mars Global Network may be seen as a precursor to the exploration of Mars by mobile vehicles in terms of its scientific measurements. But, also, some aspects of mission and system design addressed may be applicable to more complex robotic missions to Mars, for example, the development and testing of feasible probe delivery concepts; the design of low mass, low power components, and solar arrays suited for the Mars environment; and the development of a low complexity mobile instrument deployment device.

  12. Rover Traverse Planning to Support a Lunar Polar Volatiles Mission (United States)

    Heldmann, J.L.; Colaprete, A.C.; Elphic, R. C.; Bussey, B.; McGovern, A.; Beyer, R.; Lees, D.; Deans, M. C.; Otten, N.; Jones, H.; hide


    Studies of lunar polar volatile depositsare of interest for scientific purposes to understandthe nature and evolution of the volatiles, and alsofor exploration reasons as a possible in situ resource toenable long term exploration and settlement of theMoon. Both theoretical and observational studies havesuggested that significant quantities of volatiles exist inthe polar regions, although the lateral and horizontaldistribution remains unknown at the km scale and finerresolution. A lunar polar rover mission is required tofurther characterize the distribution, quantity, andcharacter of lunar polar volatile deposits at thesehigher spatial resolutions. Here we present two casestudies for NASA’s Resource Prospector (RP) missionconcept for a lunar polar rover and utilize this missionarchitecture and associated constraints to evaluatewhether a suitable landing site exists to support an RPflight mission.

  13. Flora: A Proposed Hyperspectral Mission (United States)

    Ungar, Stephen; Asner, Gregory; Green, Robert; Knox, Robert


    In early 2004, one of the authors (Stephen Ungar, NASA GSFC) presented a mission concept called "Spectrasat" at the AVIRIS Workshop in Pasadena, CA. This mission concept grew out of the lessons learned from the Earth Observing-One (EO-1) Hyperion Imaging Spectrometer and was structured to more effectively accomplish the types of studies conducted with Hyperion. The Spectrasat concept represented an evolution of the technologies and operation strategies employed on EO-I. The Spectrasat concept had been preceded by two community-based missions proposed by Susan Ustin, UC Davis and Robert Green, NASA JPL. As a result of community participation, starting at this AVIRIS Workshop, the Spectrasat proposal evolved into the Flora concept which now represents the combined visions of Gregory Asner (Carnegie Institute), Stephen Ungar, Robert Green and Robert Knox, NASA GSFC. Flora is a proposed imaging spectrometer mission, designed to address global carbon cycle science issues. This mission centers on measuring ecological disturbance for purposes of ascertaining changes in global carbon stocks and draws heavily on experience gained through AVIRIS airborne flights and Hyperion space born flights. The observing strategy exploits the improved ability of imaging spectrometers, as compared with multi-spectral observing systems, to identify vegetation functional groups, detect ecosystem response to disturbance and assess the related discovery. Flora will be placed in a sun synchronous orbit, with a 45 meter pixel size, a 90 km swath width and a 31 day repeat cycle. It covers the spectral range from 0.4 to 2.5 micrometers with a spectral sampling interval of 10 nm. These specifications meet the needs of the Flora science team under the leadership of Gregory Asner. Robert Green, has introduced a spectrometer design for Flora which is expected to have a SNR of 600: 1 in the VNIR and 450: 1 in the SWIR. The mission team at NASA GSFC is designing an Intelligent Payload Module (IPM

  14. Known unknowns: indirect energy effects of information and communication technology (United States)

    Horner, Nathaniel C.; Shehabi, Arman; Azevedo, Inês L.


    Background. There has been sustained and growing interest in characterizing the net energy impact of information and communication technology (ICT), which results from indirect effects offsetting (or amplifying) the energy directly consumed by ICT equipment. These indirect effects may be either positive or negative, and there is considerable disagreement as to the direction of this sign as well as the effect magnitude. Literature in this area ranges from studies focused on a single service (such as e-commerce versus traditional retail) to macroeconomic studies attempting to characterize the overall impact of ICT. Methods. We review the literature on the indirect energy effect of ICT found via Google Scholar, our own research, and input from other researchers in the field. The various studies are linked to an effect taxonomy, which is synthesized from several different hierarchies present in the literature. References are further grouped according to ICT service (e.g., e-commerce, telework) and summarized by scope, method, and quantitative and qualitative findings. Review results. Uncertainty persists in understanding the net energy effects of ICT. Results of indirect energy effect studies are highly sensitive to scoping decisions and assumptions made by the analyst. Uncertainty increases as the impact scope broadens, due to complex and interconnected effects. However, there is general agreement that ICT has large energy savings potential, but that the realization of this potential is highly dependent on deployment details and user behavior. Discussion. While the overall net effect of ICT is likely to remain unknown, this review suggests several guidelines for improving research quality in this area, including increased data collection, enhancing traditional modeling studies with sensitivity analysis, greater care in scoping, less confidence in characterizing aggregate impacts, more effort on understanding user behavior, and more contextual integration across the

  15. Treatment of Regional Metastatic Melanoma of Unknown Primary Origin

    Directory of Open Access Journals (Sweden)

    Elke J. A. H. van Beek


    Full Text Available (1 Background: The purpose of this retrospective study was to evaluate the recurrence and survival rates of metastatic melanoma of unknown primary origin (MUP, in order to further refine current recommendations for the surgical treatment; (2 Methods: Medical data of all MUP patients registered between 2000 and 2011, were analyzed. Seventy-eight patients were categorized in either lymph node (axilla, groin, head-and neck or subcutaneous MUP. Axillary node MUPs were generally treated with dissections of levels I-III, inguinal node MUPs with combined superficial and deep groin dissections, and head-and-neck node MUPs with neck dissections to various extents, based on lymph drainage patterns. Subcutaneous lesions were excised with 1–2 cm margins. The primary outcome was treatment outcomes in terms of (locoregional recurrence and survival rates; (3 Results: Lymph node MUP recurred regionally in 11% of patients, with an overall recurrence rate of 45%. In contrast, subcutaneous MUP recurred locally in 65% of patients with an overall recurrence rate of 78%. This latter group had a significantly shorter disease-free interval than patients with lymph node MUP (p = 0.000. In the entire study population, 5-year and 10-year overall survival rates were 56% and 47% respectively, with no differences observed between the various subgroups; (4 Conclusion: The relatively low regional recurrence rate after regional lymph node dissection (11% supports its current status as standard surgical treatment for lymph node MUP. Subcutaneous MUP, on the contrary, appears to recur both locally (65% and overall (78% at a significantly higher rate, suggesting a different biological behavior. However, wide local excision remains the best available option for this specific group.

  16. Popular Music in Jia Zhangke’s Unknown Pleasures

    Directory of Open Access Journals (Sweden)

    Jie Zhang


    Full Text Available With his documentary-style films reflecting upon China’s unprecedented transformation from a state-controlled to a market-driven economy, Jia Zhangke has risen from within the movement of independent Chinese cinema that began to flourish in the late 1990s to become one of the most recognized filmmakers of contemporary China. Born in 1970 and raised in the underdeveloped Shanxi Province, Jia studied film theory at Beijing Film Academy and was first noticed for his controversial “Hometown Trilogy”—'Pickpocket '('Xiao Wu', 1997, 'Platform '('Zhantai', 1999, and 'Unknown Pleasures '('Ren xiao yao', 2002. These three films, shot with handheld video camera on the streets of his hometown province, focus on the reckless changes that China’s aggressive economic growth and globalization have brought to socially marginalized groups. Like other independently made films—films that are produced with capital from outside the state-sponsored avenues and without the approval of film censorship, and that are not allowed to be shown in China’s public theaters—Jia’s first three films reach domestic audiences only through unofficial DVD copies and small-scaled screenings at universities, film bars, and art salons. His limited domestic influence sharply contrasts with the critical acclaim that he receives from international film festival audiences, who are searching for alternative film culture from China after the Fifth Generation directors. By the late 1990s, Jia had become a spokesperson for an ever-increasing group of aspiring Chinese independent filmmakers, particularly through writings and interviews that theorize independent Chinese cinema’s practice.

  17. Identification of unknown waste sites using MIVIS hyperspectral images

    Energy Technology Data Exchange (ETDEWEB)

    Gomarasca, M.A.; Strobelt, S. [National Research Council, Milano (Italy)


    This paper presents the results on the individuation of known and unknown (illegal) waste sites using Landsat TM satellite imagery and airborne MIVIS (Multispectral Infrared and Visible Imaging Spectrometer) data for detailed analysis in Italy. Previous results with Landsat TM imagery were partially positive for large waste site identification and negative for small sites. Information acquired by the MIVIS hyperspectral system presents three main characteristics: local scale study, possibility to plan the proper period based on the objectives of the study, high number of spectral bands with high spectral and geometrical resolution. MIVIS airborne shootings were carried out on 7 July 1994 at noon with 4x4 m pixel resolution. The MIVIS 102 bands` sensors can distinguish even objects with similar spectral behavior, thanks to its high spectral resolution. Identification of degraded sites is obtained using traditional spectral and statistical operators (NDVI, Principal Component Analysis, Maximum Likelihood classifier) and innovative combination of filtered band ratios realized to extract specific waste elements (acid slimes or contaminated soils). One of the aims that concerns with this study is the definition of an operative program for the characterization, identification and classification of defined categories of waste disposal sites. The best schedule for the data collection by airborne MIVIS oriented to this target is defined. The planning of the proper flight, based on the waste sites features, is important to optimize this technology. One of the most efficient methods for detecting hidden waste sites is the thermal inertia so two images are necessary: one during low sun load and one with high sun load. The results obtained are operationally useful and winning. This instrument, supported by correct analysis techniques, may offer new interesting prospects in territorial management and environmental monitoring. 5 refs., 5 figs., 1 tab.

  18. Adaptive vison aided integrated navigation for dynamic unknown enviroments (United States)

    Nematallah, Heba

    In this research, a novel method for visual odometry (VO) and the integration with multi-sensors navigation systems for vehicular platforms is proposed. The proposed method partitions the field of single camera view into regions of interests where each region likely contains different types of visual features. By applying computer vision processing techniques, ambiguous pose estimation is calculated up to a scale factor. The proposed method uses aiding measurements from vehicle's odometer to adaptively resolve the scale factor ambiguity problem in monocular camera systems. Unlike some state-of-art approaches, this work does not depend on offline pre-processing or predefined landmarks or visual maps. In addition, this work addresses unknown uncontrolled environments where moving objects likely exist. Innovative odometer-aided Local Bundle Adjustment (LBA) along with a fuzzy C-mean clustering mechanism is proposed to reject outliers corresponding to moving objects. A Gaussian Mixture approach is also applied to detect visual background regions during stationary periods which enables further rejection of moving objects. Finally, an empirical scoring method is applied to calculate a matching score of the different visual features and to use this score in a Kalman filter as measurement covariance noise to integrate VOestimated pose changes within a larger multi-sensors integrated navigation system. Experimental work was performed with a physical vehicular platform equipped by MEMS inertial sensors, GPS, speed measurements and GPS-enabled camera. The experimental work includes three testing vehicular trajectories in downtown Toronto and the surrounding areas. The experimental work showed significant navigation improvements during long GPS outages where only VO is fused with inertial sensors and the vehicle's speed measurements.

  19. The story of a largely unknown evolution - Germ theory hoax. (United States)

    Wainwright, Milton; Alharbi, Sulaiman Ali


    The Piltdown Man debacle provides us with the most infamous forgery in science. However, another equally intriguing story exists concerning a document by a Bostonian called George Sleeper, which purported to be a pre-Darwin-Wallace anticipation of evolution and an equally convincing account of the germ theory published before Louis Pasteur's famous studies on this subject. The story involves two giants in the world of evolutionary theory, Alfred Russel Wallace and E.B. Poulton. While Wallace was convinced that the Sleeper document was genuine, Poulton's detailed investigations showed that it was a fake and a hoax. Despite this conclusion, doubts still exist about the authenticity of the Sleeper document.

  20. Probabilistic Assessment of Cancer Risk for Astronauts on Lunar Missions (United States)

    Kim, Myung-Hee Y.; Cucinotta, Francis A.


    During future lunar missions, exposure to solar particle events (SPEs) is a major safety concern for crew members during extra-vehicular activities (EVAs) on the lunar surface or Earth-to-moon transit. NASA s new lunar program anticipates that up to 15% of crew time may be on EVA, with minimal radiation shielding. For the operational challenge to respond to events of unknown size and duration, a probabilistic risk assessment approach is essential for mission planning and design. Using the historical database of proton measurements during the past 5 solar cycles, a typical hazard function for SPE occurrence was defined using a non-homogeneous Poisson model as a function of time within a non-specific future solar cycle of 4000 days duration. Distributions ranging from the 5th to 95th percentile of particle fluences for a specified mission period were simulated. Organ doses corresponding to particle fluences at the median and at the 95th percentile for a specified mission period were assessed using NASA s baryon transport model, BRYNTRN. The cancer fatality risk for astronauts as functions of age, gender, and solar cycle activity were then analyzed. The probability of exceeding the NASA 30- day limit of blood forming organ (BFO) dose inside a typical spacecraft was calculated. Future work will involve using this probabilistic risk assessment approach to SPE forecasting, combined with a probabilistic approach to the radiobiological factors that contribute to the uncertainties in projecting cancer risks.

  1. ERDA energy information data base subject thesaurus

    Energy Technology Data Exchange (ETDEWEB)


    The technical staff of the ERDA Technical Information Center, during its subject indexing activities, develops and structures a vocabulary that allows consistent machine storage and retrieval of information necessary to the accomplishment of the ERDA mission. This thesaurus incorporates that structured vocabulary. Terms in the thesaurus are listed alphabetically; each alphabetic entry is accompanied by a ''word block'' containing all the terms associated with the entry. (RWR)

  2. Moon Age and Regolith Explorer (MARE) Mission Design and Performance (United States)

    Condon, Gerald L.; Lee, David E.; Carson, John M., III


    On December 11, 1972, Apollo 17 marked the last controlled U.S. lunar landing and was followed by an absence of methodical in-situ investigation of the lunar surface. The Moon Age and Regolith Explorer (MARE) proposal provides scientific measurement of the age and composition of a relatively young portion of the lunar surface near Aristarchus Plateau and the first post-Apollo U.S. soft lunar landing. It includes the first demonstration of a crew survivability-enhancing autonomous hazard detection and avoidance system. This report focuses on the mission design and performance associated with the MARE robotic lunar landing subject to mission and trajectory constraints.

  3. The Space Mission Design Example Using LEO Bolos

    Directory of Open Access Journals (Sweden)

    Oleg Nizhnik


    Full Text Available Four sample space launch missions were designed using rotating momentum transfer tethers (bolos within low Earth orbit and a previously unknown phenomenon of “aerospinning” was identified and simulated. The momentum transfer tethers were found to be only marginally more efficient than the use of chemical rocket boosters. Insufficient power density of modern spacecrafts was identified as the principal inhibitory factor for tether usage as a means of launch-assistance, with power densities at least 10 W/kg required for effective bolos operation.

  4. Extended mission life support systems (United States)

    Quattrone, P. D.


    Extended manned space missions which include interplanetary missions require regenerative life support systems. Manned mission life support considerations are placed in perspective and previous manned space life support system technology, activities and accomplishments in current supporting research and technology (SR&T) programs are reviewed. The life support subsystem/system technologies required for an enhanced duration orbiter (EDO) and a space operations center (SOC), regenerative life support functions and technology required for manned interplanetary flight vehicles, and future development requirements are outlined. The Space Shuttle Orbiters (space transportation system) is space cabin atmosphere is maintained at Earth ambient pressure of 14.7 psia (20% O2 and 80% N2). The early Shuttle flights will be seven-day flights, and the life support system flight hardware will still utilize expendables.


    African Journals Online (AJOL)

    The author discusses whether the issue of mission among the Jews deals with the basic question of mission or whether it is the core of the Christian faith. Although both Jews and Christians reject the idea and (more so) mission among the Jews, the author strongly argues for its need, for mission is not the expansion of ideas ...

  6. Charting the Unknown: A Hunt in the Dark (United States)

    Mohlabeng, Gopolang Mokoka

    Astrophysical and cosmological observations have pointed strongly to the existence of dark matter in the Universe, yet its nature remains elusive. It may be hidden in a vast unknown parameter space in which exhaustively searching for a signal is not feasible. We are, therefore, compelled to consider a robust program based on a wide range of new theoretical ideas and complementary strategies for detection. The aim of this dissertation is to investigate the phenomenology of diverse dark sectors with the objective of understanding and characterizing dark matter. We do so by exploring dark matter phenomenology under three main frameworks of study: (I) the model dependent approach, (II) model independent approach and (III) considering simplified models. In each framework we focus on unexplored and well motivated dark matter scenarios as well as their prospects of detection at current and future experiments. First, we concentrate on the model dependent method where we consider minimal dark matter in the form of mixed fermionic stable states in a gauge extension of the standard model. In particular, we incorporate the fermion mixings governed by gauge invariant interactions with the heavier degrees of freedom. We find that the manner of mixing has an impact on the detectability of the dark matter at experiments. Pursuing this model dependent direction, we explore a space-time extension of the standard model which houses a vector dark matter candidate. We incorporate boundary terms arising from the topology of the model and find that these control the way dark matter may interact with baryonic matter. Next we investigate the model independent approach in which we examine a non-minimal dark sector in the form of boosted dark matter. In this study, we consider an effective field theory involving two stable fermionic states. We probe the sensitivity of this type of dark matter coming from the galactic center and the center of the Sun, and investigate its detection prospects

  7. The Asteroid Impact Mission (AIM) (United States)

    Küppers, M.; Carnelli, I.; Galvez, A.; Mellab, K.; Michel, P.; AIM Team


    The Asteroid Impact Mission (AIM) is ESA's contribution to an international cooperation targeting the demonstration of deflection of a hazardous nearearth asteroid as well as the first in-depth investigation of a binary asteroid. After launch in 2020, AIM will rendezvous the binary near-Earth asteroid (65803) Didymos in 2022 and observe the system before, during, and after the impact of NASA's Double Asteroid Redirection Test (DART) spacecraft. The AIM mission will test new technologies like optical telecommunications by laser and Cubesats with nano-payloads and will perform scientific measurements at the asteroid system.

  8. Information in Repeated Ultimatum Game with Unknown Pie Size

    Directory of Open Access Journals (Sweden)

    Ching Chyi Lee


    Full Text Available Within existing literature, it is well known that people’s behavior in ultimatum game experiments cannot be explained by perfect rationality model. There is, however, evidence showing that people are boundedly rational. In this paper, we studied repeated ultimatum game experiments in which the pie size is only known to the proposer (player 1, but the transaction history is made known to both players. We found that subject’s behavior can be very well explained by the history-consistent-rationality model (HCR model of Lee and Ferguson (2010, which suggests that people’s behavior is affected by what they observed in the past. The HCR model is able to yield point predictions whose errors are on average within 5% of the total pie size. The experimental results provide evidence that subjects' behavior is boundedly rational with respect to the transaction history.

  9. Demographic window to aging in the wild: constructing life tables and estimating survival functions from marked individuals of unknown age. (United States)

    Müller, Hans-Georg; Wang, Jane-Ling; Carey, James R; Caswell-Chen, Edward P; Chen, Carl; Papadopoulos, Nikos; Yao, Fang


    Summary We address the problem of establishing a survival schedule for wild populations. A demographic key identity is established, leading to a method whereby age-specific survival and mortality can be deduced from a marked cohort life table established for individuals that are randomly sampled at unknown age and marked, with subsequent recording of time-to-death. This identity permits the construction of life tables from data where the birth date of subjects is unknown. An analogous key identity is established for the continuous case in which the survival schedule of the wild population is related to the density of the survival distribution in the marked cohort. These identities are explored for both life tables and continuous lifetime data. For the continuous case, they are implemented with statistical methods using non-parametric density estimation methods to obtain flexible estimates for the unknown survival distribution of the wild population. The analytical model provided here serves as a starting point to develop more complex models for residual demography, i.e. models for estimating survival of wild populations in which age-at-entry is unknown and using remaining information in randomly encountered individuals. This is a first step towards a broad new concept of 'expressed demographic information content of marked or captured individuals'. Copyright 2004 Blackwell Publishing Ltd.

  10. Key Gaps for Enabling Plant Growth in Future Missions (United States)

    Anderson, Molly S.; Barta, Daniel; Douglas, Grace; Fritsche, Ralph; Massa, Gioia; Wheeler, Ray; Quincy, Charles; Romeyn, Matthew; Motil, Brian; Hanford, Anthony


    Growing plants to provide food or psychological benefits to crewmembers is a common vision for the future of human spaceflight, often represented both in media and in serious concept studies. The complexity of controlled environment agriculture and of plant growth in microgravity have and continue to be the subject of dedicated scientific research. However, actually implementing these systems in a way that will be cost effective, efficient, and sustainable for future space missions is a complex, multi-disciplinary problem. Key questions exist in many areas: human research in nutrition and psychology, horticulture, plant physiology and microbiology, multi-phase microgravity fluid physics, hardware design and technology development, and system design, operations and mission planning. The criticality of the research, and the ideal solution, will vary depending on the mission and type of system implementation being considered.

  11. NASA Facts, The Viking Mission. (United States)

    National Aeronautics and Space Administration, Washington, DC. Educational Programs Div.

    Presented is one of a series of publications of National Aeronautics and Space Administration (NASA) facts about the exploration of Mars. The Viking mission to Mars, consisting of two unmanned NASA spacecraft launched in August and September, 1975, is described. A description of the spacecraft and their paths is given. A diagram identifying the…

  12. Gravitational-wave Mission Study (United States)

    Mcnamara, Paul; Jennrich, Oliver; Stebbins, Robin T.


    In November 2013, ESA selected the science theme, the "Gravitational Universe," for its third large mission opportunity, known as L3, under its Cosmic Vision Programme. The planned launch date is 2034. ESA is considering a 20% participation by an international partner, and NASA's Astrophysics Division has indicated an interest in participating. We have studied the design consequences of a NASA contribution, evaluated the science benefits and identified the technology requirements for hardware that could be delivered by NASA. The European community proposed a strawman mission concept, called eLISA, having two measurement arms, derived from the well studied LISA (Laser Interferometer Space Antenna) concept. The US community is promoting a mission concept known as SGO Mid (Space-based Gravitational-wave Observatory Mid-sized), a three arm LISA-like concept. If NASA were to partner with ESA, the eLISA concept could be transformed to SGO Mid by the addition of a third arm, augmenting science, reducing risk and reducing non-recurring engineering costs. The characteristics of the mission concepts and the relative science performance of eLISA, SGO Mid and LISA are described. Note that all results are based on models, methods and assumptions used in NASA studies

  13. The Europa Ocean Discovery mission

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, B.C. [Los Alamos National Lab., NM (United States); Chyba, C.F. [Univ. of Arizona, Tucson, AZ (United States); Abshire, J.B. [National Aeronautics and Space Administration, Greenbelt, MD (United States). Goddard Space Flight Center] [and others


    Since it was first proposed that tidal heating of Europa by Jupiter might lead to liquid water oceans below Europa`s ice cover, there has been speculation over the possible exobiological implications of such an ocean. Liquid water is the essential ingredient for life as it is known, and the existence of a second water ocean in the Solar System would be of paramount importance for seeking the origin and existence of life beyond Earth. The authors present here a Discovery-class mission concept (Europa Ocean Discovery) to determine the existence of a liquid water ocean on Europa and to characterize Europa`s surface structure. The technical goal of the Europa Ocean Discovery mission is to study Europa with an orbiting spacecraft. This goal is challenging but entirely feasible within the Discovery envelope. There are four key challenges: entering Europan orbit, generating power, surviving long enough in the radiation environment to return valuable science, and complete the mission within the Discovery program`s launch vehicle and budget constraints. The authors will present here a viable mission that meets these challenges.

  14. Modelling of the MICROSCOPE Mission (United States)

    Bremer, Stefanie; List, Meike


    The French space mission MICROSCOPE aims at testing the Equivalence Principle (EP) up to an accuracy of 10-15. The experiment will be carried out on a satellite which is developed and produced within the CNES Myriade series. The measuring accuracy will be achieved by means of two high-precision capacitive differential accelerometers that are built by the French institute ONERA, see Touboul and Rodrigues (Class. Quantum Gravity 18:2487-2498, 2001). At ZARM, which is a member of the science team, the data evaluation process is prepared. Therefore, a comprehensive simulation of the real system including the science signal and all error sources is built for the development and testing of data reduction and data analysis algorithms to extract the EP violation signal. Currently, the ZARM Drag-Free simulator, a tool to support mission modelling, is adapted for the MICROSCOPE mission in order to simulate test mass and satellite dynamics. Models of environmental disturbances like solar radiation pressure are considered, also. Additionally, detailed modelling of the on-board capacitive sensors is done. The actual status of the mission modelling will be presented. Particularly, the modelling of disturbances forces will be discussed in detail.

  15. Mission and ethics in Galatians

    African Journals Online (AJOL)



    Sep 30, 2010 ... 10.4102/hts.v67i1.896. In this article, it is investigated how the concepts identity, ethics and ethos interrelate, and ... who speak of mission in Galatians, should speak about the role of identity, ethics and ethos in the letter. ...... the perspective of speech act theory, it could be argued that Paul not only spoke.

  16. SpinSat Mission Overview (United States)


    of surface treatments. The exterior of each spacecraft has on it a beach ball type pattern consisting of gold irridite and black anodize type 2 class...cargo allotment on the SpaceX Dragon spacecraft launched by the SpaceX Falcon 9 two stage to orbit launch vehicle during the SPX-4 resupply mission

  17. The Europa Clipper Mission Concept (United States)

    Pappalardo, Robert; Goldstein, Barry; Magner, Thomas; Prockter, Louise; Senske, David; Paczkowski, Brian; Cooke, Brian; Vance, Steve; Wes Patterson, G.; Craft, Kate


    A NASA-appointed Science Definition Team (SDT), working closely with a technical team from the Jet Propulsion Laboratory (JPL) and the Applied Physics Laboratory (APL), recently considered options for a future strategic mission to Europa, with the stated science goal: Explore Europa to investigate its habitability. The group considered several mission options, which were fully technically developed, then costed and reviewed by technical review boards and planetary science community groups. There was strong convergence on a favored architecture consisting of a spacecraft in Jupiter orbit making many close flybys of Europa, concentrating on remote sensing to explore the moon. Innovative mission design would use gravitational perturbations of the spacecraft trajectory to permit flybys at a wide variety of latitudes and longitudes, enabling globally distributed regional coverage of the moon's surface, with nominally 45 close flybys at altitudes from 25 to 100 km. We will present the science and reconnaissance goals and objectives, a mission design overview, and the notional spacecraft for this concept, which has become known as the Europa Clipper. The Europa Clipper concept provides a cost-efficient means to explore Europa and investigate its habitability, through understanding the satellite's ice and ocean, composition, and geology. The set of investigations derived from the Europa Clipper science objectives traces to a notional payload for science, consisting of: Ice Penetrating Radar (for sounding of ice-water interfaces within and beneath the ice shell), Topographical Imager (for stereo imaging of the surface), ShortWave Infrared Spectrometer (for surface composition), Neutral Mass Spectrometer (for atmospheric composition), Magnetometer and Langmuir Probes (for inferring the satellite's induction field to characterize an ocean), and Gravity Science (to confirm an ocean).The mission would also include the capability to perform reconnaissance for a future lander

  18. The EXIST Mission Concept Study (United States)

    Fishman, Gerald J.; Grindlay, J.; Hong, J.


    EXIST is a mission designed to find and study black holes (BHs) over a wide range of environments and masses, including: 1) BHs accreting from binary companions or dense molecular clouds throughout our Galaxy and the Local Group, 2) supermassive black holes (SMBHs) lying dormant in galaxies that reveal their existence by disrupting passing stars, and 3) SMBHs that are hidden from our view at lower energies due to obscuration by the gas that they accrete. 4) the birth of stellar mass BHs which is accompanied by long cosmic gamma-ray bursts (GRBs) which are seen several times a day and may be associated with the earliest stars to form in the Universe. EXIST will provide an order of magnitude increase in sensitivity and angular resolution as well as greater spectral resolution and bandwidth compared with earlier hard X-ray survey telescopes. With an onboard optical-infra red (IR) telescope, EXIST will measure the spectra and redshifts of GRBs and their utility as cosmological probes of the highest z universe and epoch of reionization. The mission would retain its primary goal of being the Black Hole Finder Probe in the Beyond Einstein Program. However, the new design for EXIST proposed to be studied here represents a significant advance from its previous incarnation as presented to BEPAC. The mission is now less than half the total mass, would be launched on the smallest EELV available (Atlas V-401) for a Medium Class mission, and most importantly includes a two-telescope complement that is ideally suited for the study of both obscured and very distant BHs. EXIST retains its very wide field hard X-ray imaging High Energy Telescope (HET) as the primary instrument, now with improved angular and spectral resolution, and in a more compact payload that allows occasional rapid slews for immediate optical/IR imaging and spectra of GRBs and AGN as well as enhanced hard X-ray spectra and timing with pointed observations. The mission would conduct a 2 year full sky survey in

  19. Organizational conditions for dealing with the unknown unknown : illustrated by how a Dutch water management authority is preparing for climate change

    NARCIS (Netherlands)

    Termeer, C.J.A.M.; Brink, van den M.A.


    The central question of this article is the extent to which organizations, governmental authorities in particular, are able to deal with the unknown unknown. Drawing on Weick’s work on sensemaking, we introduce seven organizational conditions that can facilitate organizations to be reliable under

  20. Organizational Conditions for Dealing with The Unknown Unknown Illustrated by how a Dutch water management authority is preparing for climate change

    NARCIS (Netherlands)

    Termeer, Catrien J. A. M.; van den Brink, Margo A.


    The central question of this article is the extent to which organizations, governmental authorities in particular, are able to deal with the unknown unknown. Drawing on Weick's work on sensemaking, we introduce seven organizational conditions that can facilitate organizations to be reliable under

  1. IntroductionThe Cluster mission

    Directory of Open Access Journals (Sweden)

    C. P. Escoubet


    Full Text Available The Cluster mission, ESA’s first cornerstone project, together with the SOHO mission, dating back to the first proposals in 1982, was finally launched in the summer of 2000. On 16 July and 9 August, respectively, two Russian Soyuz rockets blasted off from the Russian cosmodrome in Baikonour to deliver two Cluster spacecraft, each into their proper orbit. By the end of August 2000, the four Cluster satellites had reached their final tetrahedral constellation. The commissioning of 44 instruments, both individually and as an ensemble of complementary tools, was completed five months later to ensure the optimal use of their combined observational potential. On 1 February 2001, the mission was declared operational. The main goal of the Cluster mission is to study the small-scale plasma structures in three dimensions in key plasma regions, such as the solar wind, bow shock, magnetopause, polar cusps, magnetotail and the auroral zones. With its unique capabilities of three-dimensional spatial resolution, Cluster plays a major role in the International Solar Terrestrial Program (ISTP, where Cluster and the Solar and Heliospheric Observatory (SOHO are the European contributions. Cluster’s payload consists of state-of-the-art plasma instrumentation to measure electric and magnetic fields from the quasi-static up to high frequencies, and electron and ion distribution functions from energies of nearly 0 eV to a few MeV. The science operations are coordinated by the Joint Science Operations Centre (JSOC, at the Rutherford Appleton Laboratory (UK, and implemented by the European Space Operations Centre (ESOC, in Darmstadt, Germany. A network of eight national data centres has been set up for raw data processing, for the production of physical parameters, and their distribution to end users all over the world. The latest information on the Cluster mission can be found at

  2. Essentials for Team Based Rehearsals and the Differences Between Earth Orbiting and Deep Space Missions (United States)

    Gomez-Rosa, Carlos; Cifuentes, Juan; Wasiak, Francis; Alfonzo, Agustin


    The mission readiness environment is where spacecraft and ground systems converge to form the entire as built flight system for the final phase of operationally-themed testing. For most space missions, this phase starts between nine to twelve months prior to the planned launch. In the mission readiness environment, the goal is to perform sufficient testing to exercise the flight teams and systems through all mission phases in order to demonstrate that all elements are ready to support. As part of the maturation process, a mission rehearsal program is introduced to focus on team processes within the final flight system, in a more realistic operational environment. The overall goal for a mission rehearsal program is to: 1) ensure all flight system elements are able to meet mission objectives as a cohesive team; 2) reduce the risk in space based operations due to deficiencies in people, processes, procedures, or systems; and 3) instill confidence in the teams that will execute these first time flight activities. A good rehearsal program ensures critical events are exercised, discovers team or flight system nuances whose impact were previously unknown, and provides a real-time environment in which to interact with the various teams and systems. For flight team members, the rehearsal program provides experience and training in the event of planned (or unplanned) flight contingencies. To preserve the essence for team based rehearsals, this paper will explore the important elements necessary for a successful rehearsal program, document differences driven by Earth Orbiting (Aqua, Aura, Suomi-National Polar-orbiting Partnership (NPP)) and Deep Space missions (New Horizons, Mars Atmosphere and Volatile EvolutioN (MAVEN)) and discuss common challenges to both mission types. In addition, large scale program considerations and enhancements or additional steps for developing a rehearsal program will also be considered. For NASA missions, the mission rehearsal phase is a key

  3. A subjective scheduler for subjective dedicated networks (United States)

    Suherman; Fakhrizal, Said Reza; Al-Akaidi, Marwan


    Multiple access technique is one of important techniques within medium access layer in TCP/IP protocol stack. Each network technology implements the selected access method. Priority can be implemented in those methods to differentiate services. Some internet networks are dedicated for specific purpose. Education browsing or tutorial video accesses are preferred in a library hotspot, while entertainment and sport contents could be subjects of limitation. Current solution may use IP address filter or access list. This paper proposes subjective properties of users or applications are used for priority determination in multiple access techniques. The NS-2 simulator is employed to evaluate the method. A video surveillance network using WiMAX is chosen as the object. Subjective priority is implemented on WiMAX scheduler based on traffic properties. Three different traffic sources from monitoring video: palace, park, and market are evaluated. The proposed subjective scheduler prioritizes palace monitoring video that results better quality, xx dB than the later monitoring spots.

  4. Direct-seismogram inversion for receiver-side structure with unknown source-time functions (United States)

    Dettmer, J.; Dosso, S. E.; Bodin, T.; Stipcevic, J.; Cummins, P. R.


    This work presents direct-seismogram inversion for receiver-side structure which treats the source signal incident from below (the effective source-time function, STF) as a vector of unknown parameters in a Bayesian framework. As a result, direct-seismogram inversion does not require deconvolution by observed seismogram components as typically applied in receiver-function inversion, and avoids the problematic issue of choosing subjective tuning parameters in the deconvolution. This results in more meaningful inversion results and uncertainty estimation (compared to classic receiver function inversion). A rigorous likelihood function is derived for unbiased inversion results and the STF is efficiently inferred by a maximum-likelihood closed form expression that does not require deconvolution by noisy waveforms. Rather, deconvolution is only by predicted impulse responses for the unknown environment. For a given realization of the parameter vector which describes the medium below the station, data predictions are computed as the convolution of the impulse response and the maximum-likelihood source estimate for that medium. Therefore, the assumption of a Gaussian pulse with specified parameters, typical for the prediction of receiver functions, is not required. Directly inverting seismogram components has important consequences for the noise on the data. Since the signal processing does not require filtering and deconvolution, data errors (including measurement and theory errors) appear to be less correlated and more straightforward to model than those for receiver functions. The direct-seismogram inversion is demonstrated for simulated waveforms and applied to teleseismic data recorded for station Hyderabad on the Indian craton.

  5. Can pluralistic approaches based upon unknown languages enhance learner engagement and lead to active social inclusion? (United States)

    Dahm, Rebecca


    One way to foster active social inclusion is to enable students to develop a positive attitude to "foreignness". Creating a situation where mainstream students are less wary of foreign languages and cultures, and where newcomers feel their linguistic background is being valued, provides favourable conditions for the inclusion of these newcomers in the classroom and in society. However, language classrooms in French schools rarely take any previously acquired linguistic knowledge into account, thus unconsciously contributing to the rift between multilingual learners (e.g. 1st- and 2nd-generation immigrant children, refugees, children of parents with different mother tongues) and French learners. Native French learners' first experience of learning another language is usually when English is added as a subject to their curriculum in primary school. In some schools in France, English lessons now include the simulation of multilingual situations, designed in particular for the French "quasi-monolingual" students to lose their fear of unknown languages and "foreignness" in general. But the overall aim is to help both groups of learners become aware of the positive impact of multilingualism on cognitive abilities. However, to achieve long-term effects, this awareness-raising needs to be accompanied by maximum engagement on the part of the students. This article explores an instructional strategy termed Pluralistic Approaches based upon Unknown Languages (PAUL), which was designed to develop learning strategies of quasi-monolingual students in particular and to increase learner engagement more generally. The results of a small-scale PAUL study discussed by the author seem to confirm an increase in learner engagement leading to an enhancement of learning outcomes. Moreover, PAUL seems indeed suitable for helping to prepare the ground for social inclusion.

  6. Risk of cancer of unknown primary after hospitalization for autoimmune diseases. (United States)

    Hemminki, Kari; Sundquist, Kristina; Sundquist, Jan; Ji, Jianguang


    Cancer of unknown primary (CUP) is a heterogeneous syndrome diagnosed at metastatic sites. The etiology is unknown but immune dysfunction may be a contributing factor. Patients with autoimmune diseases were identified from the Swedish Hospital Discharge Register and linked to the Swedish Cancer Registry. Standardized incidence ratios (SIRs) were calculated for subsequent CUP and compared with subjects without autoimmune diseases. A total of 789,681 patients were hospitalized for any of 32 autoimmune diseases during years 1964-2012; 2,658 developed subsequent CUP, giving an overall SIR of 1.27. A total of 16 autoimmune diseases were associated with an increased risk for CUP; polymyositis/dermatomyositis showed the highest SIR of 3.51, followed by primary biliary cirrhosis (1.81) and Addison's disease (1.77). CUP risk is known to be reduced in long-time users of pain-relieving nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin. For patients with ankylosing spondylitis and with some other autoimmune diseases, with assumed chronic medication by NSAIDSs, CUP risks decreased in long-term follow-up. The overall risk of CUP was increased among patients diagnosed with autoimmune diseases, which call for clinical attention and suggest a possible role of immune dysfunction in CUP. The associations with many autoimmune diseases were weak which may imply that autoimmunity may not synergize with CUP-related immune dysfunction. However, long-term NSAID medication probably helped to curtail risks in some autoimmune diseases and CUP risks were generally higher in autoimmune diseases for which NSAIDs are not used and for these CUP appears to be a serious side effect. © 2015 UICC.

  7. Mars sample return mission architectures utilizing low thrust propulsion (United States)

    Derz, Uwe; Seboldt, Wolfgang


    The Mars sample return mission is a flagship mission within ESA's Aurora program and envisioned to take place in the timeframe of 2020-2025. Previous studies developed a mission architecture consisting of two elements, an orbiter and a lander, each utilizing chemical propulsion and a heavy launcher like Ariane 5 ECA. The lander transports an ascent vehicle to the surface of Mars. The orbiter performs a separate impulsive transfer to Mars, conducts a rendezvous in Mars orbit with the sample container, delivered by the ascent vehicle, and returns the samples back to Earth in a small Earth entry capsule. Because the launch of the heavy orbiter by Ariane 5 ECA makes an Earth swing by mandatory for the trans-Mars injection, its total mission time amounts to about 1460 days. The present study takes a fresh look at the subject and conducts a more general mission and system analysis of the space transportation elements including electric propulsion for the transfer. Therefore, detailed spacecraft models for orbiters, landers and ascent vehicles are developed. Based on that, trajectory calculations and optimizations of interplanetary transfers, Mars entries, descents and landings as well as Mars ascents are carried out. The results of the system analysis identified electric propulsion for the orbiter as most beneficial in terms of launch mass, leading to a reduction of launch vehicle requirements and enabling a launch by a Soyuz-Fregat into GTO. Such a sample return mission could be conducted within 1150-1250 days. Concerning the lander, a separate launch in combination with electric propulsion leads to a significant reduction of launch vehicle requirements, but also requires a large number of engines and correspondingly a large power system. Therefore, a lander performing a separate chemical transfer could possibly be more advantageous. Alternatively, a second possible mission architecture has been developed, requiring only one heavy launch vehicle (e.g., Proton). In that

  8. Homicidal violence during foreign military missions - prevention and legal issues

    Directory of Open Access Journals (Sweden)

    G T Okulate


    Full Text Available Objectives. The study involved Nigerian soldiers engaged in peacekeeping missions in Liberia and Yugoslavia. Using case illustrations, the study sought to describe patterns of homicidal violence among soldiers from the same country or soldiers from allied forces, and to suggest possible reasons for the attacks. Design and setting. Nigeria was actively involved in peacekeeping missions in Liberia between 1990 and 1996. During this period, intentional homicidal attacks occurred among the Nigerian military personnel. Post- homicidal interviews conducted among the perpetrators were combined with evidence obtained at military courts to produce the case studies. Subjects. Six Nigerian military personnel who attacked other Nigerians or soldiers from allied forces, with homicidal intent. Results. Possible predisposing and precipitating factors for these attacks were highlighted. The possibility of recognising these factors before embarking on overseas missions was discussed, so that preventive measures could be instituted as far as possible. Finally, medico-legal implications of homicide in the military were discussed. Conclusions. A certain degree of pre-combat selection is essential to exclude soldiers with definite severe psychopathology. A clearly defined length of duty in the mission areas and adequate communication with home could reduce maladjustment. Health personnel deployed to mission areas should be very conversant with mental health issues so that early recognition of psychological maladjustment is possible.

  9. Probabilistic Fatigue Damage Localization at Unknown Temperatures Using Guided Wave Methods (United States)

    Hensberry, Kevin

    This research examines the current challenges of using Lamb wave interrogation methods to localize fatigue crack damage in a complex metallic structural component subjected to unknown temperatures. The goal of this work is to improve damage localization results for a structural component interrogated at an unknown temperature, by developing a probabilistic and reference-free framework for estimating Lamb wave velocities and the damage location. The methodology for damage localization at unknown temperatures includes the following key elements: i) a model that can describe the change in Lamb wave velocities with temperature; ii) the extension of an advanced time-frequency based signal processing technique for enhanced time-of-flight feature extraction from a dispersive signal; iii) the development of a Bayesian damage localization framework incorporating data association and sensor fusion. The technique requires no additional transducers to be installed on a structure, and allows for the estimation of both the temperature and the wave velocity in the component. Additionally, the framework of the algorithm allows it to function completely in an unsupervised manner by probabilistically accounting for all measurement origin uncertainty. The novel algorithm was experimentally validated using an aluminum lug joint with a growing fatigue crack. The lug joint was interrogated using piezoelectric transducers at multiple fatigue crack lengths, and at temperatures between 20°C and 80°C. The results showed that the algorithm could accurately predict the temperature and wave speed of the lug joint. The localization results for the fatigue damage were found to correlate well with the true locations at long crack lengths, but loss of accuracy was observed in localizing small cracks due to time-of-flight measurement errors. To validate the algorithm across a wider range of temperatures the electromechanically coupled LISA/SIM model was used to simulate the effects of

  10. File list: ALL.YSt.20.AllAg.Unknown [Chip-atlas[Archive

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  18. File list: InP.YSt.10.AllAg.Unknown [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.YSt.10.AllAg.Unknown sacCer3 Input control Yeast strain Unknown SRX423150,SRX38...1248,SRX390617,SRX390619 ...

  19. An Analog Rover Exploration Mission for Education and Outreach (United States)

    Moores, John; Campbell, Charissa L.; Smith, Christina L.; Cooper, Brittney A.


    This abstract describes an analog rover exploration mission designed as an outreach program for high school and undergraduate students. This program is used to teach them about basic mission control operations, how to manage a rover as if it were on another planetary body, and employing the rover remotely to complete mission objectives. One iteration of this program has been completed and another is underway. In both trials, participants were shown the different operation processes involved in a real-life mission. Modifications were made to these processes to decrease complexity and better simulate a mission control environment in a short time period (three 20-minute-long mission “days”). In the first run of the program, participants selected a landing site, what instruments would be on the rover - subject to cost, size, and weight limitations - and were randomly assigned one of six different mission operations roles, each with specific responsibilities. For example, a Science Planner/Integrator (SPI) would plan science activities whilst a Rover Engineer (RE) would keep on top of rover constraints. Planning consisted of a series of four meetings to develop and verify the current plan, pre-plan the next day's activities and uplink the activities to the “rover” (a human colleague). Participants were required to attend certain meetings depending upon their assigned role. To conclude the mission, students viewed the site to understand any differences between remote viewing and reality in relation to the rover. Another mission is currently in progress with revisions from the earlier run to improve the experience. This includes broader roles and meetings and pre-selecting the landing site and rover. The new roles are: Mission Lead, Rover Engineer and Science Planner. The SPI role was previously popular so most of the students were placed in this category. The meetings were reduced to three but extended in length. We are also planning to integrate this program

  20. Bomber Deterrence Missions: Criteria To Evaluate Mission Effectiveness (United States)


    International Relations from Brigham Young University and a Master of Science degree in Aviation Safety Management from the University of Central...Africa.2 The next year, General LeMay sent “twenty one B-47 wings on practice missions over the North Pole : eight million combat-capable miles made...effective way to persuade the enemy into believing an attack will be unsuccessful. A review of two case studies, North Korea in 2013 and Russia’s

  1. Emirates Mars Mission (EMM) Overview (United States)

    Sharaf, Omran; Amiri, Sarah; AlMheiri, Suhail; Alrais, Adnan; Wali, Mohammad; AlShamsi, Zakareyya; AlQasim, Ibrahim; AlHarmoodi, Khuloud; AlTeneiji, Nour; Almatroushi, Hessa; AlShamsi, Maryam; AlAwadhi, Mohsen; McGrath, Michael; Withnell, Pete; Ferrington, Nicolas; Reed, Heather; Landin, Brett; Ryan, Sean; Pramann, Brian


    United Arab Emirates (UAE) has entered the space exploration race with the announcement of Emirates Mars Mission (EMM), the first Arab Islamic mission to another planet, in 2014. Through this mission, UAE is to send an unmanned probe, called Hope probe, to be launched in summer 2020 and reach Mars by 2021 to coincide with UAE's 50th anniversary. Through a sequence of subsequent maneuvers, the spacecraft will enter a large science orbit that has a periapsis altitude of 20,000 km, an apoapsis altitude of 43,000 km, and an inclination of 25 degrees. The mission is designed to (1) characterize the state of the Martian lower atmosphere on global scales and its geographic, diurnal and seasonal variability, (2) correlate rates of thermal and photochemical atmospheric escape with conditions in the collisional Martian atmosphere, and (3) characterize the spatial structure and variability of key constituents in the Martian exosphere. These objectives will be met by four investigations with diurnal variability on sub-seasonal timescales which are (1) determining the three-dimensional thermal state of the lower atmosphere, (2) determining the geographic and diurnal distribution of key constituents in the lower atmosphere, (3) determining the abundance and spatial variability of key neutral species in the thermosphere, and (4) determining the three-dimensional structure and variability of key species in the exosphere. EMM will collect these information about the Mars atmospheric circulation and connections through a combination of three distinct instruments that image Mars in the visible, thermal infrared and ultraviolet wavelengths and they are the Emirates eXploration Imager (EXI), the Emirates Mars InfraRed Spectrometer (EMIRS), and the EMM Mars Ultraviolet Spectrometer (EMUS). EMM has passed its Mission Concept Review (MCR), System Requirements Review (SRR), System Design Review (SDR), and Preliminary Design Review (PDR) phases. The mission is led by Emiratis from Mohammed

  2. ESA's GOCE gravity gradiometer mission (United States)

    Touboul, Pierre


    In the present decade, three space gravity missions, CHAMP, GRACE and GOCE provide unique information about mass and mass redistribution in the Earth system with a wide range of scientific returns like global ocean circulation, ice mass balance, glacial isostatic adjustment, continental ground water storage. On board the four satellites of these missions, similar electrostatic space inertial sensors deliver continuously, during quite nine years for the older, the accurate acceleration data needed for the missions. The sensor operation remains on the six axes electrostatic suspension of one solid metallic mass, which is servo-controlled motionless at the centre of the highly stable set of gold coated silica electrode plates. All degrees of freedom are measured with very sensitive capacitive sensors down to a few pico-m and the applied electrostatic forces to pico-N. With similar sensor design and technologies, full scale range and resolution can be adjusted according to the satellite environment and the mission requirements. The CHAMP and GRACE accelerometers have demonstrated their in orbit performance. They provides measurements of the satellite non gravitational surface forces like the atmospheric drag and radiation pressures in order to extract from the satellite measured orbital position and velocity fluctuations, the effects of gravity anomalies. The six GOCE accelerometers compose the three axes gradiometer, combined to the SST-high-low GPS tracking to provide higher precision and resolution of the Earth static field. They contribute also to the satellite attitude control and drag compensation system, allowing the heliosynchronous orbit at the very low 260 km altitude. So, the accelerometers are designed to exhibit a full range of 6.5 10-6 ms-2 and a resolution of 2 10-12 ms-2 Hz-1/2. Since the gradiometer switch on in April 09, they deliver data leading to the components of the gravity gradient tensor. The main characteristics of the GOCE accelerometers and

  3. White Label Space GLXP Mission (United States)

    Barton, A.


    This poster presents a lunar surface mission concept and corresponding financing approach developed by the White Label Space team, an official competitor in the Google Lunar X PRIZE. The White Label Space team's origins were in the European Space Agency's ESTEC facility in the Netherlands. Accordingly the team's technical headquarters are located just outside ESTEC in the Space Business Park. The team has active partners in Europe, Japan and Australia. The team's goal is to provide a unique publicity opportunity for global brands to land on the moon and win the prestigious Google Lunar X PRIZE. The poster presents the main steps to achieve this goal, the cost estimates for the mission, describes the benefits to the potential sponsors and supporters, and details the progress achieved to date.

  4. Java Mission Evaluation Workstation System (United States)

    Pettinger, Ross; Watlington, Tim; Ryley, Richard; Harbour, Jeff


    The Java Mission Evaluation Workstation System (JMEWS) is a collection of applications designed to retrieve, display, and analyze both real-time and recorded telemetry data. This software is currently being used by both the Space Shuttle Program (SSP) and the International Space Station (ISS) program. JMEWS was written in the Java programming language to satisfy the requirement of platform independence. An object-oriented design was used to satisfy additional requirements and to make the software easily extendable. By virtue of its platform independence, JMEWS can be used on the UNIX workstations in the Mission Control Center (MCC) and on office computers. JMEWS includes an interactive editor that allows users to easily develop displays that meet their specific needs. The displays can be developed and modified while viewing data. By simply selecting a data source, the user can view real-time, recorded, or test data.

  5. Mission-Aware Medium Access Control in Random Access Networks


    Park, Jaeok; Van Der Schaar, Mihaela


    We study mission-critical networking in wireless communication networks, where network users are subject to critical events such as emergencies and crises. If a critical event occurs to a user, the user needs to send necessary information for help as early as possible. However, most existing medium access control (MAC) protocols are not adequate to meet the urgent need for information transmission by users in a critical situation. In this paer, we propose a novel class of MAC protocols that u...

  6. LISA Pathfinder: mission and status

    Energy Technology Data Exchange (ETDEWEB)

    Antonucci, F; Cavalleri, A; Congedo, G [Dipartimento di Fisica, Universita di Trento and INFN, Gruppo Collegato di Trento, 38050 Povo, Trento (Italy); Armano, M [European Space Astronomy Centre, European Space Agency, Villanueva de la Canada, 28692 Madrid (Spain); Audley, H; Bogenstahl, J; Danzmann, K [Albert-Einstein-Institut, Max-Planck-Institut fuer Gravitationsphysik und Universitaet Hannover, 30167 Hannover (Germany); Auger, G; Binetruy, P [APC UMR7164, Universite Paris Diderot, Paris (France); Benedetti, M [Dipartimento di Ingegneria dei Materiali e Tecnologie Industriali, Universita di Trento and INFN, Gruppo Collegato di Trento, Mesiano, Trento (Italy); Boatella, C [CNES, DCT/AQ/EC, 18 Avenue Edouard Belin, 31401 Toulouse, Cedex 9 (France); Bortoluzzi, D; Bosetti, P; Cristofolini, I [Dipartimento di Ingegneria Meccanica e Strutturale, Universita di Trento and INFN, Gruppo Collegato di Trento, Mesiano, Trento (Italy); Caleno, M; Cesa, M [European Space Technology Centre, European Space Agency, Keplerlaan 1, 2200 AG Noordwijk (Netherlands); Chmeissani, M [IFAE, Universitat Autonoma de Barcelona, E-08193 Bellaterra, Barcelona (Spain); Ciani, G [Department of Physics, University of Florida, Gainesville, FL 32611-8440 (United States); Conchillo, A [ICE-CSIC/IEEC, Facultat de Ciencies, E-08193 Bellaterra, Barcelona (Spain); Cruise, M, E-mail: [Department of Physics and Astronomy, University of Birmingham, Birmingham (United Kingdom)


    LISA Pathfinder, the second of the European Space Agency's Small Missions for Advanced Research in Technology (SMART), is a dedicated technology demonstrator for the joint ESA/NASA Laser Interferometer Space Antenna (LISA) mission. The technologies required for LISA are many and extremely challenging. This coupled with the fact that some flight hardware cannot be fully tested on ground due to Earth-induced noise led to the implementation of the LISA Pathfinder mission to test the critical LISA technologies in a flight environment. LISA Pathfinder essentially mimics one arm of the LISA constellation by shrinking the 5 million kilometre armlength down to a few tens of centimetres, giving up the sensitivity to gravitational waves, but keeping the measurement technology: the distance between the two test masses is measured using a laser interferometric technique similar to one aspect of the LISA interferometry system. The scientific objective of the LISA Pathfinder mission consists then of the first in-flight test of low frequency gravitational wave detection metrology. LISA Pathfinder is due to be launched in 2013 on-board a dedicated small launch vehicle (VEGA). After a series of apogee raising manoeuvres using an expendable propulsion module, LISA Pathfinder will enter a transfer orbit towards the first Sun-Earth Lagrange point (L1). After separation from the propulsion module, the LPF spacecraft will be stabilized using the micro-Newton thrusters, entering a 500 000 km by 800 000 km Lissajous orbit around L1. Science results will be available approximately 2 months after launch.

  7. Corot, une mission bien remplie (United States)

    Baglin, Annie; Belkacem, Kevin; Chaintreuil, Sylviane; Deleuil, Magali; Lam-Trong, Thien


    The CoRoT mission developped since 1993 was dedicated to the observation of ultra high precision measurements of the variations of stellar fluxed on long and continuous durations. His two major objectives were the detection of stellar oscillations and of extrasolar planets. A a pionnier mission, it had to invent several methods and to built the successive steps of the data treatment. They are rapidly described. The low cost 'CNES Petites Missions" programme imposed severe contraints on the instrument concept (Organisation and management, choice of the detectors, of the orbit, reduction of all parasite lights) which have been and will be guides for new generation projects. Some scientific highlights are then presented on both programmes, as for instance the use of the seismic tool as an indicator of the structure and evolution of the Galaxy, the first detection of a super-Earth, and the first precise characterisation of a brown dwarf . CoRoT has opened several avenues in instrumentation as well as science. It is shown how some aspects of this heritage have been used in the design and development of its two major heiress: CHEOPS to be launched in 2018 and the more ambitious PLATO, to be launched in 2025.

  8. The Van Allen Probes mission

    CERN Document Server

    Burch, James


    This collection of articles provides broad and detailed information about NASA’s Van Allen Probes (formerly known as the Radiation Belt Storm Probes) twin-spacecraft Earth-orbiting mission. The mission has the objective of achieving predictive understanding of the dynamic, intense, energetic, dangerous, and presently unpredictable belts of energetic particles that are magnetically trapped in Earth’s space environment above the atmosphere. It documents the science of the radiation belts and the societal benefits of achieving predictive understanding. Detailed information is provided about the Van Allen Probes mission design, the spacecraft, the science investigations, and the onboard instrumentation that must all work together to make unprecedented measurements within a most unforgiving environment, the core of Earth’s most intense radiation regions.
 This volume is aimed at graduate students and researchers active in space science, solar-terrestrial interactions and studies of the up...

  9. Subjective recovery time after exhausting muscular activity in postpolio and control subjects. (United States)

    Agre, J C; Rodriquez, A A; Franke, T M


    The purpose of this study was to determine whether the time to subjectively fully recover after the performance of exhausting muscular exercise was greater in unstable postpolio as compared with stable postpolio or control subjects. Twenty-five unstable (those complaining of declining muscle strength) postpolio, 16 stable (those denying declining muscle strength) postpolio, and 25 control subjects performed an isometric contraction of the knee extensor (quadriceps femoris) musculature at 40% of maximal torque until they were no longer able to do so. Five-second maximal effort contractions were made every 30 s through 2 min after the time of failure was reached and then at 1-min intervals through 10 min after failure was reached. Subjects reported the duration of time required to subjectively fully recover from this activity. Choices of "less than 1 day," "1 day," "2 days," etc., up to "greater than 2 wk" were given to the subjects for their response. Analysis was by nonparametric ANOVA and appropriate post hoc comparison procedures. Unstable postpolio subjects reported a greater recovery time than either the stable postpolio or control subjects (mean +/- SD of 2.6 +/- 3.0 days, 0.6 +/- 1.0 days, and 0.7 +/- 1.1 days, respectively, P postpolio subjects than stable postpolio or control subjects. The cause for this finding is unknown and requires further investigation.

  10. Cultural differences in crewmembers and mission control personnel during two space station programs. (United States)

    Boyd, Jennifer E; Kanas, Nick A; Salnitskiy, Vyacheslav P; Gushin, Vadim I; Saylor, Stephanie A; Weiss, Daniel S; Marmar, Charles R


    Cultural differences among crewmembers and mission control personnel can affect long-duration space missions. We examine three cultural contrasts: national (American vs. Russian); occupational (crewmembers vs. mission control personnel); and organizational [Mir space station vs. International Space Station (ISS)]. The Mir sample included 5 American astronauts, 8 Russian cosmonauts, and 42 American and 16 Russian mission control personnel. The ISS sample included 8 astronauts, 9 cosmonauts, and 108 American and 20 Russian mission control personnel. Subjects responded to mood and group climate questions on a weekly basis. The ISS sample also completed a culture and language questionnaire. Crewmembers had higher scores on cultural sophistication than mission control personnel, especially American mission control. Cultural sophistication was not related to mood or social climate. Russian subjects reported greater language flexibility than Americans. Crewmembers reported better mood states than mission control, but both were in the healthy range. There were several Russian-American differences in social climate, with the most robust being higher work pressure among Americans. Russian-American social climate differences were also found in analyses of crew only. Analyses showed Mir-ISS differences in social climate among crew but not in the full sample. We found evidence for national, occupational, and organizational cultural differences. The findings from the Mir space station were essentially replicated on the ISS. Alterations to the ISS to make it a more user-friendly environment have still not resolved the issue of high levels of work pressure among the American crew.


    African Journals Online (AJOL)


    Jan 30, 2010 ... 75 Elveram Street,. Lynnwood Glen, Pretoria. 0081, South Africa. Keywords: Acts; Bevansand Schroeder; contextualisation; discernment; globalisation; hospitality to strangers; inclusivity; missio Dei; missional church; missional listening; prophetic dialogue; resolving conflict. Dates: Received: 26 Aug. 2009.

  12. Low Energy Mission Planning Toolbox Project (United States)

    National Aeronautics and Space Administration — The Low Energy Mission Planning Toolbox is designed to significantly reduce the resources and time spent on designing missions in multi-body gravitational...

  13. Apollo 13 Facts [Post Mission Honorary Ceremony (United States)


    The Apollo 13 astronauts, James Lovell, Jr., John Swigert, Jr., and Fred Haise, Jr., are seen during this post mission honorary ceremony, led by President Richard Nixon. Lovell is shown during an interview, answering questions about the mission.

  14. UAV Mission Planning: From Robust to Agile

    NARCIS (Netherlands)

    Evers, L.; Barros, A.I.; Monsuur, H.; Wagelmans, A.


    Unmanned Aerial Vehicles (UAVs) are important assets for information gathering in Intelligence Surveillance and Reconnaissance (ISR) missions. Depending on the uncertainty in the planning parameters, the complexity of the mission and its constraints and requirements, different planning methods might

  15. Risk Assessment of Bone Fracture During Space Exploration Missions to the Moon and Mars (United States)

    Lewandowski, Beth E.; Myers, Jerry G.; Nelson, Emily S.; Griffin, Devon


    The possibility of a traumatic bone fracture in space is a concern due to the observed decrease in astronaut bone mineral density (BMD) during spaceflight and because of the physical demands of the mission. The Bone Fracture Risk Module (BFxRM) was developed to quantify the probability of fracture at the femoral neck and lumbar spine during space exploration missions. The BFxRM is scenario-based, providing predictions for specific activities or events during a particular space mission. The key elements of the BFxRM are the mission parameters, the biomechanical loading models, the bone loss and fracture models and the incidence rate of the activity or event. Uncertainties in the model parameters arise due to variations within the population and unknowns associated with the effects of the space environment. Consequently, parameter distributions were used in Monte Carlo simulations to obtain an estimate of fracture probability under real mission scenarios. The model predicts an increase in the probability of fracture as the mission length increases and fracture is more likely in the higher gravitational field of Mars than on the moon. The resulting probability predictions and sensitivity analyses of the BFxRM can be used as an engineering tool for mission operation and resource planning in order to mitigate the risk of bone fracture in space.

  16. SWARM - An earth Observation Mission investigating Geospace

    DEFF Research Database (Denmark)

    Friis-Christensen, Eigil; Lühr, H.; Knudsen, D.


    The Swarm mission was selected as the 5th mission in ESA's Earth Explorer Programme in 2004. This mission aims at measuring the Earth's magnetic field with unprecedented accuracy. This will be done by a constellation of three satellites, where two will fly at lower altitude, measuring the gradient...... of the Swarm science objectives, the mission concept, the scientific instrumentation, and the expected contribution to the ILWS programme will be summarized. (C) 2007 Published by Elsevier Ltd on behalf of COSPAR....

  17. CHEOPS: A transit photometry mission for ESA's small mission programme

    Directory of Open Access Journals (Sweden)

    Queloz D.


    Full Text Available Ground based radial velocity (RV searches continue to discover exoplanets below Neptune mass down to Earth mass. Furthermore, ground based transit searches now reach milli-mag photometric precision and can discover Neptune size planets around bright stars. These searches will find exoplanets around bright stars anywhere on the sky, their discoveries representing prime science targets for further study due to the proximity and brightness of their host stars. A mission for transit follow-up measurements of these prime targets is currently lacking. The first ESA S-class mission CHEOPS (CHaracterizing ExoPlanet Satellite will fill this gap. It will perform ultra-high precision photometric monitoring of selected bright target stars almost anywhere on the sky with sufficient precision to detect Earth sized transits. It will be able to detect transits of RV-planets by photometric monitoring if the geometric configuration results in a transit. For Hot Neptunes discovered from the ground, CHEOPS will be able to improve the transit light curve so that the radius can be determined precisely. Because of the host stars' brightness, high precision RV measurements will be possible for all targets. All planets observed in transit by CHEOPS will be validated and their masses will be known. This will provide valuable data for constraining the mass-radius relation of exoplanets, especially in the Neptune-mass regime. During the planned 3.5 year mission, about 500 targets will be observed. There will be 20% of open time available for the community to develop new science programmes.

  18. Biodiversity and global health—hubris, humility and the unknown (United States)

    Stephens, Carolyn


    biodiversity and well-being; and the links of biodiversity to the green economy in the context of sustainable development and poverty alleviation. References [1] Schuiteman A et al 2011 Nocturne for an unknown pollinator: first description of a night-flowering orchid (Bulbophyllum nocturnum) Bot. J. Linean Soc. 167 344-50 [2] Kinver M and Gill V 2011 Botanists discover 'remarkable' night-flowering orchid BBC News Science and Environment ( [3] Rudd M A 2011 Scientists' opinions on the global status and management of biological diversity Conserv. Biol. 25 1165-75 [4] Bottrill M C et al 2008 Is conservation triage just smart decision making? Trends Ecol. Evol. 23 649-54 [5] Parr M J et al 2009 Why we should aim for zero extinction Trends Ecol. Evol. 24 181 Bottrill M C et al 2009 Finite conservation funds mean triage is unavoidable Trends Ecol. Evol. 24 183-4 [6] Pushpangadan P and Behl H M 2005 Environment & Biodiversity: Agenda for Future (Lucknow: International Society of Environmental Botanists) ( [7] Alves R and Rosa I 2007 Biodiversity, traditional medicine and public health: where do they meet? J. Ethnobiol. Ethnomed. 3 14 [8] Center for Biodiversity and Conservation 1997 Biodiversity and Human Health: A Guide for Policymakers (New York: American Museum of Natural History) [9] Chivian E 1997 Global environmental degradation and biodiversity loss: implications for human health Biodiversity and Human Health ed F Grifo and J Rosenthal (Washington, DC: Island) pp 7-38 [10] UNEP-WCMC 2011 Health and Well Being of Communities Directly Dependent on Ecosystem Goods and Services: An Indicator for the Convention on Biological Diversity (Cambridge: UNEP-World Conservation Monitoring Centre) [11] Nettleton C, Stephens C and Bristow F 2007 Utz Wachil: a study of indigenous perceptions of health and environment in five countries Ecohealth 4 461-772 [12] Jones G P et al 2004 Coral decline

  19. Military Space Mission Design and Analysis in a Multi-Body Environment: An Investigation of High-Altitude Orbits as Alternative Transfer Paths, Parking Orbits for Reconstitution, and Unconventional Mission Orbits (United States)



  20. Telecentre Network Startup : Bangladesh - Mission 2011 | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The second generation of telecentres has seen the emergence of national-level networks in various parts of the word including the Ugandan Telecentre Network, Mission 2007 in India and Mission Swaabhimaan in Nepal. Telecentre stakeholders in Bangladesh would like to replicate the methodology used in Mission 2007, ...

  1. Kepler's Third Law and NASA's "Kepler Mission" (United States)

    Gould, Alan; Komatsu, Toshi; DeVore, Edna; Harman, Pamela; Koch, David


    NASA's "Kepler Mission" has been wildly successful in discovering exoplanets. This paper summarizes the mission goals, briefly explains the transit method of finding exoplanets and design of the mission, provides some key findings, and describes useful education materials available at the "Kepler" website.

  2. Telecentre Network Startup : Bangladesh - Mission 2011 | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The second generation of telecentres has seen the emergence of national-level networks in various parts of the word including the Ugandan Telecentre Network, Mission 2007 in India and Mission Swaabhimaan in Nepal. Telecentre stakeholders in Bangladesh would like to replicate the methodology used in Mission 2007, ...

  3. Estimating Subjective Probabilities

    DEFF Research Database (Denmark)

    Andersen, Steffen; Fountain, John; Harrison, Glenn W.

    Subjective probabilities play a central role in many economic decisions, and act as an immediate confound of inferences about behavior, unless controlled for. Several procedures to recover subjective probabilities have been proposed, but in order to recover the correct latent probability one must...

  4. Estimating Subjective Probabilities

    DEFF Research Database (Denmark)

    Andersen, Steffen; Fountain, John; Harrison, Glenn W.


    Subjective probabilities play a central role in many economic decisions and act as an immediate confound of inferences about behavior, unless controlled for. Several procedures to recover subjective probabilities have been proposed, but in order to recover the correct latent probability one must ...

  5. Subjective meaning: an introduction

    NARCIS (Netherlands)

    van Wijnbergen-Huitink, Janneke; van Wijbergen-Huitink, Janneke; Meier, Cécile

    This introductory chapter traces some of the considerations on the basis of which relativistic approaches to subjective meaning became en vogue. In doing so, the chapter provides an overview of the relevant linguistic and philosophical issues when developing a treatment of subjectivity. In addition,

  6. Subjective safety in traffic.

    NARCIS (Netherlands)


    The term ‘subjective safety in traffic’ refers to people feeling unsafe in traffic or, more generally, to anxiety regarding being unsafe in traffic for oneself and/or others. Subjective safety in traffic can lead to road users limiting their mobility and social activities, which is one of the

  7. Subjective poverty line definitions

    NARCIS (Netherlands)

    J. Flik; B.M.S. van Praag (Bernard)


    textabstractIn this paper we will deal with definitions of subjective poverty lines. To measure a poverty threshold value in terms of household income, which separates the poor from the non-poor, we take into account the opinions of all people in society. Three subjective methods will be discussed

  8. Automated Classification of Variable Stars in the Asteroseismology Program of the Kepler Space Mission

    DEFF Research Database (Denmark)

    Blomme, J.; Debosscher, J.; De Ridder, J.


    We present the first results of the application of supervised classification methods to the Kepler Q1 long-cadence light curves of a subsample of 2288 stars measured in the asteroseismology program of the mission. The methods, originally developed in the framework of the CoRoT and Gaia space...... missions, are capable of identifying the most common types of stellar variability in a reliable way. Many new variables have been discovered, among which a large fraction are eclipsing/ellipsoidal binaries unknown prior to launch. A comparison is made between our classification from the Kepler data...

  9. Chronic kidney disease of unknown aetiology in Sri Lanka: is cadmium a likely cause?

    Directory of Open Access Journals (Sweden)

    Peiris-John Roshini J


    Full Text Available Abstract Background The rising prevalence of chronic kidney disease (CKD and subsequent end stage renal failure necessitating renal replacement therapy has profound consequences for affected individuals and health care resources. This community based study was conducted to identify potential predictors of microalbuminuria in a randomly selected sample of adults from the North Central Province (NCP of Sri Lanka, where the burden of CKD is pronounced and the underlying cause still unknown. Methods Exposures to possible risk factors were determined in randomly recruited subjects (425 females and 461 males from selected areas of the NCP of Sri Lanka using an interviewer administered questionnaire. Sulphosalicylic acid and the Light Dependent Resister microalbumin gel filtration method was used for initial screening for microalbuminuria and reconfirmed by the Micral strip test. Results Microalbumnuria was detected in 6.1% of the females and 8.5% of the males. Smoking (p Conclusions Hypertension, diabetes mellitus, UTI, and smoking are known risk factors for microalbuminuria. The association between microalbuminuria and consumption of well water suggests an environmental aetiology to CKD in NCP. The causative agent is yet to be identified. Investigations for cadmium as a potential causative agent needs to be initiated.

  10. N-grams Based Supervised Machine Learning Model for Mobile Agent Platform Protection against Unknown Malicious Mobile Agents

    Directory of Open Access Journals (Sweden)

    Pallavi Bagga


    Full Text Available From many past years, the detection of unknown malicious mobile agents before they invade the Mobile Agent Platform has been the subject of much challenging activity. The ever-growing threat of malicious agents calls for techniques for automated malicious agent detection. In this context, the machine learning (ML methods are acknowledged more effective than the Signature-based and Behavior-based detection methods. Therefore, in this paper, the prime contribution has been made to detect the unknown malicious mobile agents based on n-gram features and supervised ML approach, which has not been done so far in the sphere of the Mobile Agents System (MAS security. To carry out the study, the n-grams ranging from 3 to 9 are extracted from a dataset containing 40 malicious and 40 non-malicious mobile agents. Subsequently, the classification is performed using different classifiers. A nested 5-fold cross validation scheme is employed in order to avoid the biasing in the selection of optimal parameters of classifier. The observations of extensive experiments demonstrate that the work done in this paper is suitable for the task of unknown malicious mobile agent detection in a Mobile Agent Environment, and also adds the ML in the interest list of researchers dealing with MAS security.

  11. Organochlorine pesticide level in patients with chronic kidney disease of unknown etiology and its association with renal function. (United States)

    Ghosh, Rishila; Siddarth, Manushi; Singh, Neeru; Tyagi, Vipin; Kare, Pawan Kumar; Banerjee, Basu Dev; Kalra, Om Prakash; Tripathi, Ashok Kumar


    Involvement of agrochemicals have been suggested in the development of chronic kidney disease of unknown etiology (CKDu). The association between CKDu and blood level of organochlorine pesticides (OCPs) in CKDu patients has been examined in the present study. All the recruited study subjects (n = 300) were divided in three groups, namely, healthy control (n = 100), patients with chronic kidney disease of unknown etiology (n = 100), and patients with chronic kidney disease of known etiology (CKDk) (n = 100). Blood OCP levels of all three study groups were analyzed by gas chromatography. Increased level of OCPs, namely α-HCH, aldrin, and β-endosulfan, were observed in CKDu patients as compared to healthy control and CKD patients of known etiology. The levels of these pesticides significantly correlated negatively with the estimated glomerular filtration rate (eGFR) and positively with urinary albumin of CKD patients. Logistic regression analysis revealed association of γ-HCH, p, p'-DDE, and β-endosulfan with CKDu on adjustment of age, sex, BMI, and total lipid content. Increased blood level of certain organochlorine pesticides is associated with the development of chronic kidney disease of unknown etiology.

  12. The Ionospheric Connection Explorer Mission: Mission Goals and Design (United States)

    Immel, T. J.; England, S. L.; Mende, S. B.; Heelis, R. A.; Englert, C. R.; Edelstein, J.; Frey, H. U.; Korpela, E. J.; Taylor, E. R.; Craig, W. W.; Harris, S. E.; Bester, M.; Bust, G. S.; Crowley, G.; Forbes, J. M.; Gérard, J.-C.; Harlander, J. M.; Huba, J. D.; Hubert, B.; Kamalabadi, F.; Makela, J. J.; Maute, A. I.; Meier, R. R.; Raftery, C.; Rochus, P.; Siegmund, O. H. W.; Stephan, A. W.; Swenson, G. R.; Frey, S.; Hysell, D. L.; Saito, A.; Rider, K. A.; Sirk, M. M.


    The Ionospheric Connection Explorer, or ICON, is a new NASA Explorer mission that will explore the boundary between Earth and space to understand the physical connection between our world and our space environment. This connection is made in the ionosphere, which has long been known to exhibit variability associated with the sun and solar wind. However, it has been recognized in the 21st century that equally significant changes in ionospheric conditions are apparently associated with energy and momentum propagating upward from our own atmosphere. ICON's goal is to weigh the competing impacts of these two drivers as they influence our space environment. Here we describe the specific science objectives that address this goal, as well as the means by which they will be achieved. The instruments selected, the overall performance requirements of the science payload and the operational requirements are also described. ICON's development began in 2013 and the mission is on track for launch in 2018. ICON is developed and managed by the Space Sciences Laboratory at the University of California, Berkeley, with key contributions from several partner institutions.

  13. Magnetospheric Multiscale (MMS) Mission Status (United States)

    Moore, T. E.; Black, R.; Burch, J. L.; Hesse, M.; Robertson, B. P.; Spidaliere, P. D.; Pope, S.; Tooley, C. R.; Torbert, R. B.


    The MMS mission, with its four fully instrumented reconnection probes, is manifested for launch in March 2015 from Kennedy Space Center (KSC). The initial orbits will be 12 RE geocentric radius by 1200 km altitude at 28˚ inclination, maneuvered into a resizable tetrahedral formation that will pass through the persistent sites of magnetic reconnection nearest to Earth. The Observatories, each with suite of instruments, underwent thermal vacuum testing serially beginning in late Nov 2013, with the final testing completed in July 2014. Pre-Shipment Review was held in late October 2014 prior to shipment of stacked pairs of Observatories to the launch processing site at KSC (Astrotech). They are now being processed in stacked pairs, pending full stacking as a constellation and installation on the Atlas V - Series 421 launch vehicle that will carry them into orbit. Final propulsion functional testing and launch rehearsal operations will be conducted this month. The Science and Engineering Team is preparing for commissioning and early operations immediately after launch by executing Mission Readiness Tests (MRTs) to exercise all systems including the "Scientist In The Loop" or SITL system that will provide human oversight of the prioritization of high resolution data segments for downloading to the ground. The Theory and Modeling team and three Interdisciplinary Science teams continue to develop virtual spacecraft data sets and displays as an aid to identification of features of interest during operations. Phase 1 operations will probe the dayside low latitude reconnection features, beginning in August 2015, as the constellation moves into the afternoon local time sector. More information is available at,, and other linked sites.

  14. Mission Design of the Dutch-Chinese FAST Micro-Satellite Mission

    NARCIS (Netherlands)

    Maessen, D.C.; Guo, J.; Gill, E.; Laan, E.; Moon, S.; Zheng, G.T.


    The paper treats the mission design for the Dutch-Chinese FAST (Formation for Atmospheric Science and Technology demonstration) mission. The space segment of the 2.5 year mission consists out of two formation flying micro-satellites. During the mission, new technologies will be demonstrated and,

  15. Unifying Subjectivity and Objectivity

    Directory of Open Access Journals (Sweden)

    Murugesan Chandrasekaran


    Full Text Available The contribution of modern science to the progress of civilization is immeasurable. Even its tendency toward exclusive concentration on the objective world has had salutary effects of great value. Modern science has wiped away much that was merely superstitious or speculative. Its rejection of unfounded opinions and prejudices has helped the thinking mind question conventional beliefs, shed preferences and prejudices, and challenge established authority. But modern systems thinking inherited from natural science is the suppression of the subjective dimension of reality. Many complex systems are an attempt to define and represent all subjective experience in physical terms. The modern man has a bias towards objectivity. The powerful influence of sense impressions on his mind and thinking makes him ignore the subjective experience and consider only objective facts as a valid, legitimate and representation of reality. Observing objective factors that are physical is easier than observing subjective factors that are subtle. The mechanistic view of reality has led to the rejection of the role of the individual in social development as insignificant. The individuals determine the development of society. Their social power has its roots both in subjective factors and objective factors. Economy, politics, society, and culture are inseparable dimensions of a single integrated reality. Subject and object constitute an integrated whole. The mind sees them as separate and independent. Or it views one as completely subordinate to the other. Unbiased approach to the study of all human experiences may prove that subject and object are interdependent dimensions or elements of reality.

  16. Kepler planet-detection mission

    DEFF Research Database (Denmark)

    Borucki...[], William J.; Koch, David; Buchhave, Lars C. Astrup


    The Kepler mission was designed to determine the frequency of Earth-sized planets in and near the habitable zone of Sun-like stars. The habitable zone is the region where planetary temperatures are suitable for water to exist on a planet’s surface. During the first 6 weeks of observations, Kepler...... is one of the lowest-density planets (~0.17 gram per cubic centimeter) yet detected. Kepler-5b, -6b, and -8b confirm the existence of planets with densities lower than those predicted for gas giant planets....

  17. The GeoCarb Mission (United States)

    Moore, B., III; Crowell, S.


    This paper presents a space mission (geoCARB) that would provide measurements of atmospheric carbon dioxide (CO2), methane (CH4), and carbon monoxide (CO) from geostationary orbit. The geoCARB mission would deliver multiple daily maps of column integrated mixing ratios of CO2, CH4, and CO over the observed landmasses at a spatial resolution of roughly 5 x 8 km., which will establish the scientific basis for CO2 and CH4 flux determination at the unprecedented time and space scale. This determination would produce a fundamental change in our scientific understanding of the terrestrial source/sink dynamics of carbon cycle as well as produce the kind of flux information that would be needed to support international agreements on greenhouse gas emission reductions. The instrument would exploit four spectral regions: The Oxygen A-band for pressure and aerosols, the weak and strong bands of CO2 near 1.61 and 2.06 microns, and a region near 2.32 microns for CO and CH4. The O2 and CO2 band selection are very similar to the instrument aboard OCO-2, and so we envision OCO-2 in geostationary orbit with the addition of a fourth channel to measure CO and CH4, but without an oceanic capability. The O2 A-band also provides for retrieval of Solar Induced Fluoresce (SIF). The geoCARB Mission's persistent fine-scale mapping-like measurements, multiple times a day under changing conditions, enable significant advances on an important range of CO2 issues: CO2 fertilization, change in primary production because of nitrogen deposition, and the influence of climatic patterns on terrestrial sources and sinks. Similarly, the mission's high space- and time-measurements of CH4 enable important analyses of human impacts via agriculture and industry vs. natural phenomena on methane sources. The geoCARB measurements of CO concentrations and SIF provide essential information for CO2 and CH4 source attribution. For example, CO helps distinguish between biotic fluxes of CO2 and CH4 from fluxes

  18. NASA CYGNSS Tropical Cyclone Mission (United States)

    Ruf, Chris; Atlas, Robert; Majumdar, Sharan; Ettammal, Suhas; Waliser, Duane


    The NASA Cyclone Global Navigation Satellite System (CYGNSS) mission consists of a constellation of eight microsatellites that were launched into low-Earth orbit on 15 December 2016. Each observatory carries a four-channel bistatic scatterometer receiver to measure near surface wind speed over the ocean. The transmitter half of the scatterometer is the constellation of GPS satellites. CYGNSS is designed to address the inadequacy in observations of the inner core of tropical cyclones (TCs) that result from two causes: 1) much of the TC inner core is obscured from conventional remote sensing instruments by intense precipitation in the eye wall and inner rain bands; and 2) the rapidly evolving (genesis and intensification) stages of the TC life cycle are poorly sampled in time by conventional polar-orbiting, wide-swath surface wind imagers. The retrieval of wind speed by CYGNSS in the presence of heavy precipitation is possible due to the long operating wavelength used by GPS (19 cm), at which scattering and attenuation by rain are negligible. Improved temporal sampling by CYGNSS is possible due to the use of eight spacecraft with 4 scatterometer channels on each one. Median and mean revisit times everywhere in the tropics are 3 and 7 hours, respectively. Wind speed referenced to 10m height above the ocean surface is retrieved from CYGNSS measurements of bistatic radar cross section in a manner roughly analogous to that of conventional ocean wind scatterometers. The technique has been demonstrated previously from space by the UK-DMC and UK-TDS missions. Wind speed is retrieved with 25 km spatial resolution and an uncertainty of 2 m/s at low wind speeds and 10% at wind speeds above 20 m/s. Extensive simulation studies conducted prior to launch indicate that there will be a significant positive impact on TC forecast skill for both track and intensity with CYGNSS measurements assimilated into HWRF numerical forecasts. Simulations of CYGNSS spatial and temporal sampling

  19. Asteroseismology with NASA's Kepler Mission

    DEFF Research Database (Denmark)

    Huber, Daniel; Chaplin, W. J.; Christensen-Dalsgaard, J.


    The measurement of stellar oscillations - also called asteroseismology - is among the most powerful observational tools to study the structure and evolution of stars. The high precision photometry collected by the Kepler space telescope has revolutionized asteroseismology over the past few years...... by boosting the number of stars with detected oscillations by nearly two orders of magnitude over ground-based efforts, and delivering data with unprecedented signal-to-noise. In this talk I will highlight some of the recent breakthrough discoveries by the Kepler Mission, focusing in particular...

  20. Bion 11 mission: primate experiments (United States)

    Ilyin, E. A.; Korolkov, V. I.; Skidmore, M. G.; Viso, M.; Kozlovskaya, I. B.; Grindeland, R. E.; Lapin, B. A.; Gordeev, Y. V.; Krotov, V. P.; Fanton, J. W.; hide


    A summary is provided of the major operations required to conduct the wide range of primate experiments on the Bion 11 mission, which flew for 14 days beginning December 24, 1996. Information is given on preflight preparations, including flight candidate selection and training; attachment and implantation of bioinstrumentation; flight and ground experiment designs; onboard life support and test systems; ground and flight health monitoring; flight monkey selection and transport to the launch site; inflight procedures and data collection; postflight examinations and experiments; and assessment of results.

  1. Magnetic Satellite Missions and Data

    DEFF Research Database (Denmark)

    Olsen, Nils; Kotsiaros, Stavros


    Although the first satellite observations of the Earth’s magnetic field were already taken more than 50 years ago, continuous geomagnetic measurements from space are only available since 1999. The unprecedented time-space coverage of this recent data set opened revolutionary new possibilities...... for exploring the Earth’s magnetic field from space. In this chapter we discuss characteristics of satellites measuring the geomagnetic field and report on past, present and upcoming magnetic satellite missions. We conclude with some basics about space magnetic gradiometry as a possible path for future...... exploration of Earth’s magnetic field with satellites....


    Directory of Open Access Journals (Sweden)

    D.N. Bakhrakh


    Full Text Available The question about the subjects of law branches is concerning the number of most important and difficult in law science. Its right decision influences on the subject of law regulation, precise definition of addressees of law norms, the volume of their rights and duties, the limits of action of norms of Main part of the branch, its principles. Scientific investigations, dedicated to law subjects system, promote the development of recommendations for the legislative and law applying activity; they are needed for scientific work organization and student training, for preparing qualified lawyers.

  3. Subjective Straight Ahead Orientation in Microgravity (United States)

    Clement, G.; Reschke, M. F.; Wood, S. J.


    This joint ESA NASA study will address adaptive changes in spatial orientation related to the subjective straight ahead and the use of a vibrotactile sensory aid to reduce perceptual errors. The study will be conducted before and after long-duration expeditions to the International Space Station (ISS) to examine how spatial processing of target location is altered following exposure to microgravity. This study addresses the sensorimotor research gap to "determine the changes in sensorimotor function over the course of a mission and during recovery after landing."

  4. Crew Transportation System Design Reference Missions (United States)

    Mango, Edward J.


    Contains summaries of potential design reference mission goals for systems to transport humans to andfrom low Earth orbit (LEO) for the Commercial Crew Program. The purpose of this document is to describe Design Reference Missions (DRMs) representative of the end-to-end Crew Transportation System (CTS) framework envisioned to successfully execute commercial crew transportation to orbital destinations. The initial CTS architecture will likely be optimized to support NASA crew and NASA-sponsored crew rotation missions to the ISS, but consideration may be given in this design phase to allow for modifications in order to accomplish other commercial missions in the future. With the exception of NASA’s mission to the ISS, the remaining commercial DRMs are notional. Any decision to design or scar the CTS for these additional non-NASA missions is completely up to the Commercial Provider. As NASA’s mission needs evolve over time, this document will be periodically updated to reflect those needs.

  5. Mission design of a Pioneer Jupiter Orbiter (United States)

    Friedman, L. D.; Nunamaker, R. R.


    The Mission analysis and design work performed in order to define a Pioneer mission to orbit Jupiter is described. This work arose from the interaction with a science advisory 'Mission Definition' team and led to the present mission concept. Building on the previous Jupiter Orbiter-Satellite Tour development at JPL a magnetospheric survey mission concept is developed. The geometric control of orbits which then provide extensive local time coverage of the Jovian system is analyzed and merged with the various science and program objectives. The result is a 'flower-orbit' mission design, yielding three large apoapse excursions at various local times and many interior orbits whose shape and orientation is under continual modification. This orbit design, together with a first orbit defined by delivery of an atmospheric probe, yields a mission of high scientific interest.

  6. Astronaut Brian Duffy, mission commander for the STS-72 mission, prepares to ascend stairs to the (United States)


    STS-72 TRAINING VIEW --- Astronaut Brian Duffy, mission commander for the STS-72 mission, prepares to ascend stairs to the flight deck of the fixed base Shuttle Mission Simulator (SMS) at the Johnson Space Center (JSC). Duffy will be joined by four other NASA astronauts and an international mission specialist aboard the Space Shuttle Endeavour for a scheduled nine-day mission, now set for the winter of this year.

  7. Astronaut Leroy Chiao, assigned as mission specialist for the mission, prepares to ascend stairs to (United States)


    STS-72 TRAINING VIEW --- Astronaut Leroy Chiao, assigned as mission specialist for the mission, prepares to ascend stairs to the flight deck of the fixed base Shuttle Mission Simulator (SMS) at the Johnson Space Center (JSC). Chiao will join an international mission specialist and four other NASA astronauts aboard the Space Shuttle Endeavour for a scheduled nine-day mission, now set for the winter of this year.

  8. The BIOMASS mission — An ESA Earth Explorer candidate to measure the BIOMASS of the earth's forests

    DEFF Research Database (Denmark)

    Scipal, K.; Arcioni, M.; Chave, J.


    The European Space Agency (ESA) released a Call for Proposals for the next Earth Explorer Core Mission in March 2005, with the aim to select the 7th Earth Explorer (EE-7) mission for launch in the next decade. Twenty-four proposals were received and subject to scientific and technical assessment...

  9. ESA's Future Earth Explorer: new candidate mission concepts (United States)

    Drinkwater, M.; Ingmann, P.; Kern, M.; Langen, J.; Drusch, M.; Davidson, M.; Bensi, P.; Carnicero, B.; Thompson, A.; Silvestrin, P.; Lin, C.; Heliere, F.; Bezy, J.; Durand, Y.; Aguirre, M.; Haagmans, R.


    The European Space Agency has released the call for the next Earth Explorer Core Mission Ideas in March 2005 with the aim to select the 7th Earth Explorer mission to be launched in the 2014 timeframe. Twenty-four proposals were received and subject to detailed scientific and technical assessment. Six proposals have been selected to be further investigated in a detailed scientific and technical assessment study, after which a down-selection will be made. The six candidate missions selected are: A-SCOPE - (Advanced Space Carbon and Climate Observation of Planet Earth): Improving the understanding of the global carbon cycle and regional carbon dioxide fluxes, BIOMASS - global measurements of forest biomass and extent, CoReH2O - (Cold Regions Hydrology High-resolution Observatory): Detailed observations of key snow, ice and water cycle characteristics, FLEX - (FLuorescence EXplorer): Observation of global photosynthesis through the measurement of fluorescence, PREMIER - (PRocess Exploration through Measurements of Infrared and millimetre- wave Emitted Radiation): Understanding the processes that link trace gases, radiation, chemistry and climate in the atmosphere and TRAQ - (TRopospheric composition and Air Quality) - Air quality monitoring and long-range transport of air pollutants. This paper will give an overview of the science objectives and preliminary requirement specifications for each candidate mission. A user concultation meeting will be held at the Congress Centre of the Belém Cultural Centre in Lisbon, Portugal, on 20-21 January 2009 to proceed with selected ones in feasibility study.

  10. Updated Heliostorm Warning Mission: Enhancements Based on New Technology (United States)

    Young, Roy M.


    The Heliostorm (also referred to as Geostorm) mission has been regarded as the best choice for the first application of solar sail technology. The objective of Heliostorm is to obtain data from an orbit station slightly displaced from the ecliptic at or nearer to the Sun than 0.98 AU, which places it twice as close to the sun as Earth's natural L1 point at 0.993 AU. Heliostorm has been the subject of several mission studies over the past decade, with the most complete study conducted in 1999 in conjunction with a proposed New Millennium Program (NMP) Space Technology 5 (ST-5) flight opportunity. Recently, over a two and one-half year period dating from 2002 through 2005, NASA s In-Space Propulsion Technology Program (ISTP) matured solar sail technology from laboratory components to fully integrated systems, demonstrated in as relevant a space environment as could feasibly be simulated on the ground. Work under this program has yielded promising results for enhanced Heliostorm mission performance. This paper will present the preliminary results of an updated Heliostorm mission design study including the enhancements incorporated during the design, development, analysis and testing of the system ground demonstrator.

  11. Shuttle Radar Topography Mission (SRTM) (United States)



    Under an agreement with the National Aeronautics and Space Administration (NASA) and the Department of Defense's National Geospatial-Intelligence Agency (NGA), the U.S. Geological Survey (USGS) is distributing elevation data from the Shuttle Radar Topography Mission (SRTM). The SRTM is a joint project of NASA and NGA to map the Earth's land surface in three dimensions at an unprecedented level of detail. As part of space shuttle Endeavour's flight during February 11-22, 2000, the SRTM successfully collected data over 80 percent of the Earth's land surface for most of the area between latitudes 60 degrees north and 56 degrees south. The SRTM hardware included the Spaceborne Imaging Radar-C (SIR-C) and X-band Synthetic Aperture Radar (X-SAR) systems that had flown twice previously on other space shuttle missions. The SRTM data were collected with a technique known as interferometry that allows image data from dual radar antennas to be processed for the extraction of ground heights.

  12. FUSE Mission Overview and Status (United States)

    Sonneborn, G.

    The Far Ultraviolet Spectroscopic Explorer satellite observes light in the 905-1187 Å region with high spectral resolution (λ/Δλ ~ 20,000). FUSE was launched on 24 June 1999 and the early observations have yielded significant results in several areas of galactic and extragalactic astronomy. The sensitivity is sufficient to examine reddened lines of sight within the Milky Way as well as active galactic nuclei and QSOs for absorption line studies of both Milky Way and extragalactic gas clouds. This spectral region contains a number of important scientific diagnostics, including O VI, H I, D I, and the strong electronic transitions of the H2 and HD molecules. The instrument has four coaligned prime-focus telescopes and Rowland spectrographs with microchannel plate detectors. Two channels use Al:LiF coatings for optimum reflectivity from ~ 1000 to 1187 Å and the other two use SiC coatings for optimized throughput between 905 and 1105 Å. The gratings were holographically ruled to largely correct for astigmatism and to minimize scattered light. The detectors have KBr photocathodes and use photon counting to achieve good quantum efficiency with low background signal. The primary mission duration is three years; an extended mission phase is planned. A majority of the observing time is allocated to guest observers. (

  13. The Cassini-Huygens mission

    CERN Document Server

    The joint NASA-ESA Cassini-Huygens mission promises to return four (and possibly more) years of unparalleled scientific data from the solar system’s most exotic planet, the ringed, gas giant, Saturn. Larger than Galileo with a much greater communication bandwidth, Cassini can accomplish in a single flyby what Galileo returned in a series of passes. Cassini explores the Saturn environment in three dimensions, using gravity assists to climb out of the equatorial plane to look down on the rings from above, to image the aurora and to study polar magnetospheric processes such as field-aligned currents. Since the radiation belt particle fluxes are much more benign than those at Jupiter, Cassini can more safely explore the inner regions of the magnetosphere. The spacecraft approaches the planet closer than Galileo could, and explores the inner moons and the rings much more thoroughly than was possible at Jupiter. This book is the second volume, in a three volume set, that describes the Cassini/Huygens mission. Thi...


    Directory of Open Access Journals (Sweden)

    F. Gandor


    Full Text Available This paper presents a development of an open-source flight planning tool for Remotely Piloted Aircraft Systems (RPAS that is dedicated to high-precision photogrammetric mapping. This tool contains planning functions that are usually available in professional mapping systems for manned aircrafts as well as new features related to GPS signal masking in complex (e.g. mountainous terrain. The application is based on the open-source Java SDK (Software Development Kit World Wind from NASA that contains the main geospatial components facilitating the development itself. Besides standard planning functions known from other mission planners, we mainly focus on additional features dealing with safety and accuracy, such as GPS quality assessment. The need for the development came as a response for unifying mission planning across different platforms (e.g. rotary or fixed wing operating over terrain of different complexity. A special attention is given to the user interface, that is intuitive to use and cost-effective with respect to computer resources.

  15. The Data Subject

    DEFF Research Database (Denmark)

    Blume, Peter


    This article considers whether it is fortunate that data protection rules, as a starting point, apply to all physical persons as data subjects, or whether it would be better to differentiate between kinds of persons on grounds of their ability to act as a data subject. In order to protect all...... persons, it is argued that a principle of care should be part of data protection law....

  16. Governing the Entrepreneurial Mindset: Business Students' Constructions of Entrepreneurial Subjectivity (United States)

    Laalo, Hanna; Heinonen, Jarna


    Promoting entrepreneurship education to develop the entrepreneurial competences and mindsets of citizens has become an important mission on the supranational educational policy agenda. This endeavour constructs the ideal of a self-guided entrepreneurial subject who is active, adaptable and capable of tolerating uncertainty. Using the theorizations…

  17. Mission objectives and scientific rationale for the magnetometer mission. (United States)

    Langel, R. A.


    Based on a review of the characteristics of the geomagnetic field, objectives for the magnetic portion of the ARISTOTELES mission are: (1) To derive a description of the main magnetic field and its secular variation. (2) To investigate the correlation between the geomagnetic field and variations in the length of day. (3) To study properties of the fluid core. (4) To study the conductivity of the mantle. (5) To model the state and evolution of the crust and upper lithosphere. (6) To measure and characterize field aligned currents and ionospheric currents and to understand their generation mechanisms and their role in energy coupling in the interplanetary-magnetospheric-ionospheric systems. Procedures for these investigations are outlined.

  18. Autonomous Reactive Mission Scheduling and Task-Path Planning Architecture for Autonomous Underwater Vehicle


    Zadeh, Somaiyeh Mahmoud


    An Autonomous Underwater Vehicle (AUV) should carry out complex tasks in a limited time interval. Since existing AUVs have limited battery capacity and restricted endurance, they should autonomously manage mission time and the resources to perform effective persistent deployment in longer missions. Task assignment requires making decisions subject to resource constraints, while tasks are assigned with costs and/or values that are budgeted in advance. Tasks are distributed in a particular oper...

  19. Spacelab Mission Implementation Cost Assessment (SMICA) (United States)

    Guynes, Buddy V.


    Concern by top NASA management in late 1982 that the cost to accomplish Spacelab Payload Integration and Operations appeared excessive and not well understood, led to the initiation of the Spacelab Mission Implementation Cost Assessment (SMICA) study. SMICA was chartered to a "bottoms up study" to define an accurate cost model for a reference mission, and to develop an implementation plan for reducing these costs. All phases of this Spacelab mission were considered including payload mission management, experiment and mission peculiar equipment development, mission integration and ground and flight operations, and science/engineering data evaluation. Excluded were the functions and costs for the Shuttle, Spacelab Data Processing Facility, and the Tracking and Data Relay Satellite System (TDRSS). The study did establish a baseline mission cost for reference. The base-line mission payload included five new instruments and four reflight instruments. SMICA showed that a total savings of approximately 20% could be attained if the following were accomplished: 1. Compress the mission management and ground processing schedules. 2. Revise the approach to equipping, staffing, and operating the Payload Operations Control Center. 3. Change the methods of working with the experiment developers (science community). The operating philosophies and procedures recommended can serve as generic guidelines to other Spacelab mission/payload managers in reducing overall cost/manpower requirements. Attainment of maximum benefit from the assessment entails the addition of some risk, and this will be discussed briefly in the report.

  20. Space Launch System Mission Flexibility Assessment (United States)

    Monk, Timothy; Holladay, Jon; Sanders, Terry; Hampton, Bryan


    The Space Launch System (SLS) is envisioned as a heavy lift vehicle that will provide the foundation for future beyond low Earth orbit (LEO) missions. While multiple assessments have been performed to determine the optimal configuration for the SLS, this effort was undertaken to evaluate the flexibility of various concepts for the range of missions that may be required of this system. These mission scenarios include single launch crew and/or cargo delivery to LEO, single launch cargo delivery missions to LEO in support of multi-launch mission campaigns, and single launch beyond LEO missions. Specifically, we assessed options for the single launch beyond LEO mission scenario using a variety of in-space stages and vehicle staging criteria. This was performed to determine the most flexible (and perhaps optimal) method of designing this particular type of mission. A specific mission opportunity to the Jovian system was further assessed to determine potential solutions that may meet currently envisioned mission objectives. This application sought to significantly reduce mission cost by allowing for a direct, faster transfer from Earth to Jupiter and to determine the order-of-magnitude mass margin that would be made available from utilization of the SLS. In general, smaller, existing stages provided comparable performance to larger, new stage developments when the mission scenario allowed for optimal LEO dropoff orbits (e.g. highly elliptical staging orbits). Initial results using this method with early SLS configurations and existing Upper Stages showed the potential of capturing Lunar flyby missions as well as providing significant mass delivery to a Jupiter transfer orbit.

  1. Space Shuttle Mission 41-C Official crew photo (United States)


    Space Shuttle Mission 41-C Official crew photo. From left to right: Robert Crippen, crew commander; Terry Hart, mission specialist; James van Hoften, mission specialist; George Nelson, mission specialist; and Francis (Dick) Scobee, pilot.

  2. Space Mission : Y3K (United States)


    ESA and the APME are hosting a contest for 10 - 15 year olds in nine European countries (Austria, Belgium, France, Germany, Italy, the Netherlands, Spain, Sweden and the United Kingdom). The contest is based on an interactive CD ROM, called Space Mission: Y3K, which explores space technology and shows some concrete uses of that technology in enhancing the quality of life on Earth. The CD ROM invites kids to join animated character Space Ranger Pete on an action-packed, colourful journey through space. Space Ranger Pete begins on Earth: the user navigates around a 'locker room' to learn about synthetic materials used in rocket boosters, heat shields, space suits and helmets, and how these materials have now become indispensable to everyday life. From Earth he flies into space and the user follows him from the control room in the spacecraft to a planet, satellites and finally to the International Space Station. Along the way, the user jots down clues that he or she discovers in this exploration, designing an imaginary space community and putting together a submission for the contest. The lucky winners will spend a weekend training as "junior astronauts" at the European Space Centre in Belgium (20-22 April 2001). They will be put through their astronaut paces, learning the art of space walking, running their own space mission, piloting a space capsule and re-entering the Earth's atmosphere. The competition features in various youth media channels across Europe. In the UK, popular BBC Saturday morning TV show, Live & Kicking, will be launching the competition and will invite viewers to submit their space community designs to win a weekend at ESC. In Germany, high circulation children's magazine Geolino will feature the competition in the January issue and on their internet site. And youth magazine ZoZitDat will feature the competition in the Netherlands throughout February. Space Mission: Y3K is part of an on-going partnership between the ESA's Technology Transfer

  3. Bone Metabolism on ISS Missions (United States)

    Smith, S. M.; Heer, M. A.; Shackelford, L. C.; Zwart, S. R.


    Spaceflight-induced bone loss is associated with increased bone resorption (1, 2), and either unchanged or decreased rates of bone formation. Resistive exercise had been proposed as a countermeasure, and data from bed rest supported this concept (3). An interim resistive exercise device (iRED) was flown for early ISS crews. Unfortunately, the iRED provided no greater bone protection than on missions where only aerobic and muscular endurance exercises were available (4, 5). In 2008, the Advanced Resistive Exercise Device (ARED), a more robust device with much greater resistance capability, (6, 7) was launched to the ISS. Astronauts who had access to ARED, coupled with adequate energy intake and vitamin D status, returned from ISS missions with bone mineral densities virtually unchanged from preflight (7). Bone biochemical markers showed that while the resistive exercise and adequate energy consumption did not mitigate the increased bone resorption, bone formation was increased (7, 8). The typical drop in circulating parathyroid hormone did not occur in ARED crewmembers. In 2014, an updated look at the densitometry data was published. This study confirmed the initial findings with a much larger set of data. In 42 astronauts (33 male, 9 female), the bone mineral density response to flight was the same for men and women (9), and those with access to the ARED did not have the typical decrease in bone mineral density that was observed in early ISS crewmembers with access to the iRED (Figure 1) (7). Biochemical markers of bone formation and resorption responded similarly in men and women. These data are encouraging, and represent the first in-flight evidence in the history of human space flight that diet and exercise can maintain bone mineral density on long-duration missions. However, the maintenance of bone mineral density through bone remodeling, that is, increases in both resorption and formation, may yield a bone with strength characteristics different from those

  4. Austere Human Missions to Mars (United States)

    Price, Hoppy; Hawkins, Alisa M.; Tadcliffe, Torrey O.


    The Design Reference Architecture 5 (DRA 5) is the most recent concept developed by NASA to send humans to Mars in the 2030 time frame using Constellation Program elements. DRA 5 is optimized to meet a specific set of requirements that would provide for a robust exploration program to deliver a new six-person crew at each biennial Mars opportunity and provide for power and infrastructure to maintain a highly capable continuing human presence on Mars. This paper examines an alternate architecture that is scaled back from DRA 5 and might offer lower development cost, lower flight cost, and lower development risk. It is recognized that a mission set using this approach would not meet all the current Constellation Mars mission requirements; however, this 'austere' architecture may represent a minimum mission set that would be acceptable from a science and exploration standpoint. The austere approach is driven by a philosophy of minimizing high risk or high cost technology development and maximizing development and production commonality in order to achieve a program that could be sustained in a flat-funded budget environment. Key features that would enable a lower technology implementation are as follows: using a blunt-body entry vehicle having no deployable decelerators, utilizing aerobraking rather than aerocapture for placing the crewed element into low Mars orbit, avoiding the use of liquid hydrogen with its low temperature and large volume issues, using standard bipropellant propulsion for the landers and ascent vehicle, and using radioisotope surface power systems rather than a nuclear reactor or large area deployable solar arrays. Flat funding within the expected NASA budget for a sustained program could be facilitated by alternating cargo and crew launches for the biennial Mars opportunities. This would result in two assembled vehicles leaving Earth orbit for Mars per Mars opportunity. The first opportunity would send two cargo landers to the Mars surface to

  5. Human rhinovirus infections in symptomatic and asymptomatic subjects

    Directory of Open Access Journals (Sweden)

    C.N. Camargo


    Full Text Available The role of rhinovirus asymptomatic infections in the transmission among close contacts subjects is unknown. We tested health care workers, a pair of one child and a family member and immunocompromised patients (n =191. HRV were detected on 22.9% symptomatic and 3.6% asymptomatic cases suggesting lower transmission among contacts.

  6. Hepatitis B immunisation in persons not previously exposed to hepatitis B or with unknown exposure status

    DEFF Research Database (Denmark)

    Mathew, Joseph L; El Dib, Regina; Mathew, Preethy J


    The benefits and harms of hepatitis B vaccination in persons not previously exposed to hepatitis B infection or with unknown exposure status have not been established.......The benefits and harms of hepatitis B vaccination in persons not previously exposed to hepatitis B infection or with unknown exposure status have not been established....

  7. Detection of unknown primary head and neck tumors by positron emission tomography

    NARCIS (Netherlands)

    Braams, JW; Pruim, J; Kole, AC; Nikkels, PGJ; Vaalburg, W; Vermey, A; Roodenburg, JLN

    The purpose of this study was to investigate the potential of using positron emission tomography (PET) with F-18-labeled fluoro-2-deoxy-D-glucose (FDG) to detect unknown primary tumors of cervical metastases. Thirteen patients with various histologic types of cervical metastases of unknown primary

  8. Fast grasping of unknown objects using cylinder searching on a single point cloud

    NARCIS (Netherlands)

    Lei, Q.; Wisse, M.; Verikas, Antanas; Radeva, Petia; Nikolaev, Dmitry P.; Zhang, Wei; Zhou, Jianhong


    Grasping of unknown objects with neither appearance data nor object models given in advance is very important for robots that work in an unfamiliar environment. The goal of this paper is to quickly synthesize an executable grasp for one unknown object by using cylinder searching on a single point

  9. Grand Challenge Problems in Real-Time Mission Control Systems for NASA's 21st Century Missions (United States)

    Pfarr, Barbara B.; Donohue, John T.; Hughes, Peter M.


    Space missions of the 21st Century will be characterized by constellations of distributed spacecraft, miniaturized sensors and satellites, increased levels of automation, intelligent onboard processing, and mission autonomy. Programmatically, these missions will be noted for dramatically decreased budgets and mission development lifecycles. Current progress towards flexible, scaleable, low-cost, reusable mission control systems must accelerate given the current mission deployment schedule, and new technology will need to be infused to achieve desired levels of autonomy and processing capability. This paper will discuss current and future missions being managed at NASA's Goddard Space Flight Center in Greenbelt, MD. It will describe the current state of mission control systems and the problems they need to overcome to support the missions of the 21st Century.

  10. Aquarius/SAC-D mission (United States)

    Sen, Amit; Caruso, Daniel; Lagerloef, Gary; Torrusio, Sandra; Durham, David; Falcon, Carlos


    Sea Surface Salinity (SSS) is a key parameter in the global water cycle but it is not yet monitored from space. Conventional in situ SSS sampling is too sparse to give the global view of salinity variability that a remote sensing satellite can provide. The Aquarius/SAC-D Mission will make pioneering space-based measurements of global SSS with the precision, resolution, and coverage needed to characterize salinity variations (spatial and temporal), investigate the linkage between ocean circulation, the Earth's water cycle, and climate variability. It is being jointly developed by NASA and the Space Agency of Argentina, the Comision Nacional de Actividades Espaciales (CONAE). The Project is currently in implementation phase with the flight Aquarius Instrument undergoing environmental testing at NASA-JPL/Caltech in California, USA and the SAC-D instruments and spacecraft development undergoing at CONAE/INVAP facilities in Argentina. Aquarius/SAC-D launch is scheduled for May 2010.

  11. Job Orders (Ordres de mission)

    CERN Document Server

    Organisation & Procedures, FI Department, Tel. 73905


    Please note that individual job orders and continuous job orders (valid for one calendar year, i.e. from 1st January to 31st December) must henceforth be completed via EDH and approved by the Department Leader concerned (or the person appointed by him via EDHAdmin). Once approved, the form must be printed and kept for the duration of the mission by the driver to whom the job order is issued. You will find the icon for this document on the EDH Desktop, as well as on-line help on how to use it. In emergencies, paper copies of individual job orders (SCEM may be issued outside normal working hours by the Fire Brigade (Meyrin Site, Building 65). Organisation & Procedures, FI Department, Tel. 73905 Relations with the Host States Service, Tel. 72848

  12. The Global Precipitation Measurement Mission (United States)

    Jackson, Gail


    The Global Precipitation Measurement (GPM) mission's Core satellite, scheduled for launch at the end of February 2014, is well designed estimate precipitation from 0.2 to 110 mm/hr and to detect falling snow. Knowing where and how much rain and snow falls globally is vital to understanding how weather and climate impact both our environment and Earth's water and energy cycles, including effects on agriculture, fresh water availability, and responses to natural disasters. The design of the GPM Core Observatory is an advancement of the Tropical Rainfall Measuring Mission (TRMM)'s highly successful rain-sensing package [3]. The cornerstone of the GPM mission is the deployment of a Core Observatory in a unique 65o non-Sun-synchronous orbit to serve as a physics observatory and a calibration reference to improve precipitation measurements by a constellation of 8 or more dedicated and operational, U.S. and international passive microwave sensors. The Core Observatory will carry a Ku/Ka-band Dual-frequency Precipitation Radar (DPR) and a multi-channel (10-183 GHz) GPM Microwave Radiometer (GMI). The DPR will provide measurements of 3-D precipitation structures and microphysical properties, which are key to achieving a better understanding of precipitation processes and improving retrieval algorithms for passive microwave radiometers. The combined use of DPR and GMI measurements will place greater constraints on possible solutions to radiometer retrievals to improve the accuracy and consistency of precipitation retrievals from all constellation radiometers. Furthermore, since light rain and falling snow account for a significant fraction of precipitation occurrence in middle and high latitudes, the GPM instruments extend the capabilities of the TRMM sensors to detect falling snow, measure light rain, and provide, for the first time, quantitative estimates of microphysical properties of precipitation particles. The GPM Core Observatory was developed and tested at NASA

  13. The SSETI-express Mission

    DEFF Research Database (Denmark)

    Alminde, Lars; Bisgaard, Morten; Melville, N.

    provides a description of the organisation behind the project and the mission of the satellite. Further it provides a technical overview of both the space segment and the ground segment together with key lessons learnt from the process of building a student satellite with widely distributed teams.......In January 2004 a group of students met at the European Space Technology and Research Centre (ESTEC) in Holland to discuss the feasibility of building a micro-satellite, dubbed SSETI-Express, from parts derived from other student satellite projects and launch it within one and a half year....... The project is an initiative under the ESA Education Department and the Student Space Exploration and Technology Initiative (SSETI)[3], an European student organisation. The satellite is currently scheduled for launch on the 30th of June 2005 atop a "Cosmos" launch vehicle from Plesetsk in Russia. This paper...

  14. The SSETI-Express Mission

    DEFF Research Database (Denmark)

    Alminde, Lars; Bisgaard, Morten; Melville, Neil


    provides a description of the organisation behind the project and the mission of the satellite. Further it provides a technical overview of both the space segment and the ground segment together with key lessons learnt from the process of building a student satellite with widely distributed teams.......In January 2004 a group of students met at the European Space Technology and Research Centre (ESTEC) in Holland to discuss the feasibility of building a micro-satellite, dubbed SSETI-Express, from parts derived from other student satellite projects and launch it within one and a half year....... The project is an initiative under the ESA Education Department and the Student Space Exploration and Technology Initiative (SSETI)[3], an European student organisation. The satellite is currently scheduled for launch on the 30th of June 2005 atop a "Cosmos" launch vehicle from Plesetsk in Russia. This paper...

  15. Challenges of Space Mission Interoperability (United States)

    Martin, Warren L.; Hooke, Adrian J.


    This viewgraph presentation reviews some of the international challenges to space mission interoperability. Interoperability is the technical capability of two or more systems or components to exchange information and to use the information that has been exchanged. One of the challenges that is addressed is the problem of spectrum bandwidth, and interference. The key to interoperability is the standardization of space communications services and protocols. Various levels of international cross support are reviewed: harmony, cooperation cross support and confederation cross support. The various international bodies charged with implementing cross support are reviewed. The goal of the Interagency Operations Advisory Group (IOAG) is to achieve plug-and-play operations where all that is required is for each of the systems to use an agreed communications medium, after which the systems configure each other for the purpose of exchanging information and subsequently effect such exchange automatically.

  16. LISA Pathfinder: A Mission Status (United States)

    Hewitson, Martin; LISA Pathfinder Team Team


    On December 3rd at 04:04 UTC, The European Space Agency launched the LISA Pathfinder satellite on board a VEGA rocket from Kourou in French Guiana. After a series of orbit raising manoeuvres and a 2 month long transfer orbit, LISA Pathfinder arrived at L1. Following a period of commissioning, the science operations commenced at the start of March, beginning the demonstration of technologies and methodologies which pave the way for a future large-scale gravitational wave observatory in space. This talk will present the scientific goals of the mission, discuss the technologies being tested, elucidate the link to a future space-based observatory, such as LISA, and present preliminary results from the in-orbit operations and experiments.


    Directory of Open Access Journals (Sweden)

    Mario Bertaina


    Full Text Available The JEM-EUSO mission explores the origin of the extreme energy cosmic rays (EECRs above 50EeV and explores the limits of the fundamental physics, through the observations of their arrival directions and energies. It is designed to open a new particle astronomy channel. This superwide-field (60 degrees telescope with a diameter of about 2.5m looks down from space onto the night sky to detect near UV photons (330 ÷ 400nm, both fluorescent and Cherenkov photons emitted from the giant air showers produced by EECRs. The arrival direction map with more than five hundred events will tell us the origin of the EECRs and allow us to identify the nearest EECR sources with known astronomical objects. It will allow them to be examined in other astronomical channels. This is likely to lead to an  nderstanding of the acceleration mechanisms perhaps producing discoveries in astrophysics and/or fundamental physics. The comparison of the energy spectra among the spatially resolved individual sources will help to clarify the acceleration/emission mechanism, and also finally confirm the Greisen–Zatsepin–Kuz’min process for the validation of Lorentz invariance up to γ ~ 1011. Neutral components (neutrinos and gamma rays can also be detected as well, if their fluxes are high enough. The JEM-EUSO mission is planned to be launched by a H2B rocket about 2017 and transferred to ISS by H2 Transfer Vehicle (HTV. It will be attached to the Exposed Facility external experiment platform of “KIBO”.

  18. The Shuttle Radar Topography Mission (United States)

    Farr, T. G.; Kobrick, M.


    The Shuttle Radar Topography Mission (SRTM), which flew successfully aboard Endeavour in February 2000, is a cooperative project between NASA, the National Imagery and Mapping Agency, and the German and Italian Space Agencies. The mission was designed to use a single-pass radar interferometer to produce a digital elevation model of the Earth's land surface between about 60 degrees north and 56 degrees south latitude. The DEM will have 30 m horizontal resolution and better than 15 m vertical errors. Two ortho-rectified C-band image mosaics are also planned. Data processing will be completed by the end of 2002. SRTM used a modification of the radar instrument that comprised the Spaceborne Radar Laboratory that flew twice on the Shuttle Endeavour in 1994. To collect the interferometric data, a 60 m mast, additional C-band antenna, and improved tracking and navigation devices were added. A second X-band antenna was also added by the German Space Agency, and produced higher resolution topographic measurements in strips nested within the full, C-band coverage. First results indicate that the radars and ancillary instruments worked very well. Data played back to the ground during the flight were processed to DEMs and products released hours after acquisition. An extensive program for calibration and verification of the SRTM data is now underway. When complete later this year, systematic processing of the data will begin, with final products emerging a continent at a time. Products will be transferred to the US Geological Survey's EROS Data Center for civilian archive and distribution. NIMA will handle Department of Defense distribution. * Work performed under contract to NASA.

  19. Subject (of documents)

    DEFF Research Database (Denmark)

    Hjørland, Birger


    such as concepts, aboutness, topic, isness and ofness are also briefly presented. The conclusion is that the most fruitful way of defining “subject” (of a document) is the documents informative or epistemological potentials, that is, the documents potentials of informing users and advance the development......This article presents and discuss the concept “subject” or subject matter (of documents) as it has been examined in library and information science (LIS) for more than 100 years. Different theoretical positions are outlined and it is found that the most important distinction is between document......-oriented views versus request-oriented views. The document-oriented view conceive subject as something inherent in documents, whereas the request-oriented view (or the policy based view) understand subject as an attribution made to documents in order to facilitate certain uses of them. Related concepts...

  20. The Quest for a European Space Mission in Stellar Seismology and Planet Finding (United States)

    Roxburgh, Ian W.


    The idea of a space mission for stellar activity and seismology was conceived in France 1981-2 and underwent a series of developments leading to the EVRIS experiment as a passenger experiment on Mars96. Modified versions of EVRIS were proposed for other missions including SOHO, and it was eventually launched on Mars96 and immediately lost when Mars96 failed. In parallel more ambitious and larger missions were proposed to ESA including PRISMA, STARS and Eddington. CoRoT was originally conceived as a follow up mission to EVRIS but has matured into the present CNES/International project that is the subject of this volume. Initially these missions were devoted to stellar seismology and activity, but were expanded to incorporate searching for planets. The Eddington mission was initially selected by ESA in 2000 with reserve status, then fully approved in 2002, but withdrawn from the ESA programme in 2004, as part of the programme reduction needed to solve the financial problems of ESA's Science Programme. The small Danish seismology mission MONS was approved in 2002 but also subsequently cancelled, whereas the Canadian microsatellite mission MOST was proposed in 1997, successfully launched in 2003 and is currently collecting data.

  1. Science of the subjective. (United States)

    Jahn, R G; Dunne, B J


    Over the greater portion of its long scholarly history, the particular form of human observation, reasoning, and technical deployment we properly term "science" has relied at least as much on subjective experience and inspiration as it has on objective experiments and theories. Only over the past few centuries has subjectivity been progressively excluded from the practice of science, leaving an essentially secular analytical paradigm. Quite recently, however, a compounding constellation of newly inexplicable physical evidence, coupled with a growing scholarly interest in the nature and capability of human consciousness, are beginning to suggest that this sterilization of science may have been excessive and could ultimately limit its epistemological reach and cultural relevance. In particular, an array of demonstrable consciousness-related anomalous physical phenomena, a persistent pattern of biological and medical anomalies, systematic studies of mind/brain relationships and the mechanics of human creativity, and a burgeoning catalogue of human factors effects within contemporary information processing technologies, all display empirical correlations with subjective aspects that greatly complicate, and in many cases preclude, their comprehension on strictly objective grounds. However, any disciplined re-admission of subjective elements into rigorous scientific methodology will hinge on the precision with which they can be defined, measured, and represented, and on the resilience of established scientific techniques to their inclusion. For example, any neo-subjective science, while retaining the logical rigor, empirical/theoretical dialogue, and cultural purpose of its rigidly objective predecessor, would have the following requirements: acknowledgment of a proactive role for human consciousness; more explicit and profound use of interdisciplinary metaphors; more generous interpretations of measurability, replicability, and resonance; a reduction of ontological

  2. Agile: From Software to Mission System (United States)

    Trimble, Jay; Shirley, Mark H.; Hobart, Sarah Groves


    The Resource Prospector (RP) is an in-situ resource utilization (ISRU) technology demonstration mission, designed to search for volatiles at the Lunar South Pole. This is NASA's first near real time tele-operated rover on the Moon. The primary objective is to search for volatiles at one of the Lunar Poles. The combination of short mission duration, a solar powered rover, and the requirement to explore shadowed regions makes for an operationally challenging mission. To maximize efficiency and flexibility in Mission System design and thus to improve the performance and reliability of the resulting Mission System, we are tailoring Agile principles that we have used effectively in ground data system software development and applying those principles to the design of elements of the mission operations system.

  3. The first Spacelab mission. [payload management functions (United States)

    Pace, R. E., Jr.


    The purpose of Spacelab, an Orbiter-mounted NASA/ESA laboratory, is to include in the Space Transportation System (STS) a payload carrier with maximum flexibility to accommodate multidisciplinary scientific payloads. The major Spacelab configurations obtained by combination of two basic elements, the module and pallet, are described along with the anticipated program of experiments and payloads, and mission management general concept. The first Spacelab 7-day mission is scheduled for flight in the second half of 1980, with the primary objective being to verify system performance capabilities. Detailed attention is given to the payload mission management responsibilities for the first flight, including program control, science management, payload interfaces, integrated payload mission planning, integration requirements, payload specialist training, payload integration, launch site integration, payload flight/mission operations, and postmission activities. The Spacelab configuration (including the long module and one pallet) and the overall schedule for this mission are presented.

  4. The Subjectivity of Participation

    DEFF Research Database (Denmark)

    Nissen, Morten

    What is a 'we' – a collective – and how can we use such communal self-knowledge to help people? This book is about collectivity, participation, and subjectivity – and about the social theories that may help us understand these matters. It also seeks to learn from the innovative practices and ideas...... practices. Through this dialogue, it develops an original trans-disciplinary critical theory and practice of collective subjectivity for which the ongoing construction and overcoming of common sense, or ideology, is central. It also points to ways of relating discourse with agency, and fertilizing insights...... from interactionism and ideology theories in a cultural-historical framework....

  5. The usage of fasting glucose and glycated hemoglobin for the identification of unknown type 2 diabetes in high risk patients with morbid obesity. (United States)

    Valderhaug, Tone G; Sharma, Archana; Kravdal, Gunnhild; Rønningen, Reidun; Nermoen, Ingrid


    In spite of increased vigilance of undiagnosed type 2 diabetes (DM2), the prevalence of unknown DM2 in subjects with morbid obesity is not known. To assess the prevalence of undiagnosed DM2 and compare the performance of glycated A1c (HbA1c) and fasting glucose (FG) for the diagnosis of DM2 and prediabetes (preDM) in patients with morbid obesity. We measured fasting glucose and HbA1c in 537 consecutive patients with morbid obesity without previously known DM2. A total of 49 (9%) patients with morbid obesity had unknown DM2 out of which 16 (33%) fulfilled both the criteria for HbA1c and FG. Out of 284 (53%) subjects with preDM, 133 (47%) fulfilled both the criteria for HbA1c and FG. Measurements of agreement for FG and HbA1c were moderate for DM2 (κ = 0.461, p DM2 were 0.970 (95% CI 0.942, 0.998) and 0.894 (95% CI 0.837, 0.951) respectively. The optimal thresholds to identify unknown DM2 were FG ≥6.6 mmol/L and HbA1c ≥ 6.1% (43 mmol/mol). The prevalence of DM2 remains high and both FG and HbA1c identify patients with unknown DM2. FG was slightly superior to HbA1c in predicting and separating patients with unknown DM2 from patients without DM2. We suggest that an FG ≥6.6 mmol/L or an HbA1c ≥6.1% (43 mmol/mol) may be used as primary cut points for the identification of unknown DM2 among patients with morbid obesity.

  6. Sleep, Circadian Rhythms, and Performance During Space Shuttle Missions (United States)

    Neri, David F.; Czeisler, Charles A.; Dijk, Derk-Jan; Wyatt, James K.; Ronda, Joseph M.; Hughes, Rod J.


    Sleep and circadian rhythms may be disturbed during spaceflight, and these disturbances can affect crewmembers' performance during waking hours. The mechanisms underlying sleep and circadian rhythm disturbances in space are not well understood, and effective countermeasures are not yet available. We investigated sleep, circadian rhythms, cognitive performance, and light-dark cycles in five astronauts prior to, during, and after the 16-day STS-90 mission and the IO-day STS-95 mission. The efficacy of low-dose, alternative-night, oral melatonin administration as a countermeasure for sleep disturbances was evaluated. During these missions, scheduled rest activity cycles were 20-35 minutes shorter than 24 hours. Light levels on the middeck and in the Spacelab were very low; whereas on the flight deck (which has several windows), they were highly variable. Circadian rhythm abnormalities were observed. During the second half of the missions, the rhythm of urinary cortisol appeared to be delayed relative to the sleep-wake schedule. Performance during wakefulness was impaired. Astronauts slept only about 6.5 hours per day, and subjective sleep quality was lower in space. No beneficial effects of melatonin (0.3 mg administered prior to sleep episodes on alternate nights) were observed. A surprising finding was a marked increase in rapid eye movement (REM) sleep upon return to Earth. We conclude that these Space Shuttle missions were associated with circadian rhythm disturbances, sleep loss, decrements in neurobehavioral performance, and alterations in REM sleep homeostasis. Shorter than 24-hour rest-activity schedules and exposure to light-dark cycles inadequate for optimal circadian synchronization may have contributed to these disturbances.

  7. Prevalence of detecting unknown cerebral metastases in fluorodeoxyglucose positron emission tomography/computed tomography and its potential clinical impact. (United States)

    Kung, Boom Ting; Auyong, T K; Tong, C M


    To determine the prevalence of incidental finding of unknown cerebral metastases and explore the clinical impact of detecting unknown brain metastases among individuals underwent whole body fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) with brain included in field of view. A retrospective review of 1876 patients who underwent whole body PET/CT examination in our clinical PET center for oncological evaluation from January 2009 to September 2009 was performed. The total number and prevalence of unknown brain metastases detected by PET/CT were calculated. Patients diagnosed with cerebral metastases by PET/CT were further analyzed via the electronic patient record system for relevant clinical and radiological findings. Positive predictive value of PET/CT for the diagnosis of cerebral metastases was calculated with reference to contrast enhanced magnetic resonance imaging (MRI) or contrast enhanced CT. Of the 1876 subjects, 71 patients (3.8%) were diagnosed with cerebral metastases by PET/CT. 31 patients were already diagnosed with brain metastases before PET/CT. Among the 40 patients with unknown brain metastasis, 24 (60.0%) underwent either MRI (n = 5) or CT (n = 19) after PET/CT, of which 17 patients were confirmed with cerebral metastases. The true positive rate was 70.8% (17/24), while the false positive rate of PET/CT was 29.2% (7/24). Nearly 94.1% (16/17) patients with confirmed cerebral metastases on MRI or CT had subsequent change in management. Among the remaining 16 patients with positive findings of cerebral metastases without further radiological correlation, 43.8% (7/16) patients had change in management after PET/CT. A total of 57.5% (23/40) patients had change in management after PET/CT. The point prevalence of detecting unknown cerebral metastases by PET/CT was 2.1% (40/1876). 94.1% patients with newly diagnosed brain metastases confirmed with either MRI or CT received immediate treatment for cerebral

  8. Key Gaps for Enabling Plant Growth in Future Missions (United States)

    Anderson, Molly; Motil, Brian; Barta, Dan; Fritsche, Ralph; Massa, Gioia; Quincy, Charlie; Romeyn, Matthew; Wheeler, Ray; Hanford, Anthony


    Growing plants to provide food or psychological benefits to crewmembers is a common vision for the future of human spaceflight, often represented in media and in serious concept studies. The complexity of controlled environment agriculture, and plant growth in microgravity have and continue to be the subject of dedicated scientific research. However, actually implementing these systems in a way that will be cost effective, efficient, and sustainable for future space missions is a complex, multi-disciplinary problem. Key questions exist in many areas: human medical research in nutrition and psychology, horticulture, plant physiology and microbiology, multi-phase microgravity fluid physics, hardware design and technology development, and system design, operations and mission planning. This paper describes key knowledge gaps identified by a multi-disciplinary working group within the National Aeronautics and Space Administration (NASA). It also begins to identify solutions to the simpler questions identified by the group based on work initiated in 2017. Growing plants to provide food or psychological benefits to crewmembers is a common vision for the future of human spaceflight, often represented in media and in serious concept studies. The complexity of controlled environment agriculture, and plant growth in microgravity have and continue to be the subject of dedicated scientific research. However, actually implementing these systems in a way that will be cost effective, efficient, and sustainable for future space missions is a complex, multi-disciplinary problem. Key questions exist in many areas: human medical research in nutrition and psychology, horticulture, plant physiology and microbiology, multi-phase microgravity fluid physics, hardware design and technology development, and system design, operations and mission planning. This paper describes key knowledge gaps identified by a multi-disciplinary working group within the National Aeronautics and Space

  9. Mission Power and Firm Financial Performance


    Téllez, Diego; Godoy, Jésus


    We estimate the effect from mission statement on firm financial performance in a sample of Colombian companies. The mission power, a latent variable defined by using tools from word content analysis, is included in a structural equation model to compute its impact across two channels: the profit margin and the assets turnover. Our estimates show that the no-significant impact of mission statement, which is documented in the literature, may be caused by the opposite effect that sales amount in...

  10. Agile: From Software to Mission Systems (United States)

    Trimble, Jay; Shirley, Mark; Hobart, Sarah


    To maximize efficiency and flexibility in Mission Operations System (MOS) design, we are evolving principles from agile and lean methods for software, to the complete mission system. This allows for reduced operational risk at reduced cost, and achieves a more effective design through early integration of operations into mission system engineering and flight system design. The core principles are assessment of capability through demonstration, risk reduction through targeted experiments, early test and deployment, and maturation of processes and tools through use.

  11. GSFC Safety and Mission Assurance Organization (United States)

    Kelly, Michael P.


    This viewgraph presentation reviews NASA Goddard Space Flight Center's approach to safety and mission assurance. The contents include: 1) NASA GSFC Background; 2) Safety and Mission Assurance Directorate; 3) The Role of SMA-D and the Technical Authority; 4) GSFC Mission assurance Requirements; 5) GSFC Systems Review Office (SRO); 6) GSFC Supply Chain Management Program; and 7) GSFC ISO9001/AS9100 Status Brief.

  12. Autolanding for Sample Return Missions Project (United States)

    National Aeronautics and Space Administration — Future NASA and commercial missions will increasingly target destinations with challenging topography and limited communication including unmapped asteroids, comets,...

  13. ESPA for Lunar and Science Missions Project (United States)

    National Aeronautics and Space Administration — NASA mission planning in the next decade includes small spacecraft and secondary flight opportunities on Evolved Expendable Launch Vehicles (EELVs), specifically...

  14. Rapid Automated Mission Planning System Project (United States)

    National Aeronautics and Space Administration — The proposed innovation is an automated UAS mission planning system that will rapidly identify emergency (contingency) landing sites, manage contingency routing, and...

  15. Sustainable, Reliable Mission-Systems Architecture (United States)

    O'Neil, Graham; Orr, James K.; Watson, Steve


    A mission-systems architecture, based on a highly modular infrastructure utilizing: open-standards hardware and software interfaces as the enabling technology is essential for affordable and sustainable space exploration programs. This mission-systems architecture requires (a) robust communication between heterogeneous system, (b) high reliability, (c) minimal mission-to-mission reconfiguration, (d) affordable development, system integration, and verification of systems, and (e) minimal sustaining engineering. This paper proposes such an architecture. Lessons learned from the Space Shuttle program and Earthbound complex engineered system are applied to define the model. Technology projections reaching out 5 years are mde to refine model details.

  16. Space Mission Human Reliability Analysis (HRA) Project (United States)

    Boyer, Roger


    The purpose of the Space Mission Human Reliability Analysis (HRA) Project is to extend current ground-based HRA risk prediction techniques to a long-duration, space-based tool. Ground-based HRA methodology has been shown to be a reasonable tool for short-duration space missions, such as Space Shuttle and lunar fly-bys. However, longer-duration deep-space missions, such as asteroid and Mars missions, will require the crew to be in space for as long as 400 to 900 day missions with periods of extended autonomy and self-sufficiency. Current indications show higher risk due to fatigue, physiological effects due to extended low gravity environments, and others, may impact HRA predictions. For this project, Safety & Mission Assurance (S&MA) will work with Human Health & Performance (HH&P) to establish what is currently used to assess human reliabiilty for human space programs, identify human performance factors that may be sensitive to long duration space flight, collect available historical data, and update current tools to account for performance shaping factors believed to be important to such missions. This effort will also contribute data to the Human Performance Data Repository and influence the Space Human Factors Engineering research risks and gaps (part of the HRP Program). An accurate risk predictor mitigates Loss of Crew (LOC) and Loss of Mission (LOM).The end result will be an updated HRA model that can effectively predict risk on long-duration missions.

  17. Tank waste remediation system (TWRS) mission analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rieck, R.H.


    The Tank Waste Remediation System Mission Analysis provides program level requirements and identifies system boundaries and interfaces. Measures of success appropriate to program level accomplishments are also identified.

  18. Paying Hypertension Research Subjects (United States)

    Casarett, David; Karlawish, Jason; Asch, David A


    CONTEXT Cash payments are often used to compensate subjects who participate in research. However, ethicists have argued that these payments might constitute an undue inducement. OBJECTIVES To determine whether potential subjects agree with theoretical arguments that a payment could be an undue inducement. DESIGN/SETTING/PARTICIPANTS Survey of 350 prospective jurors. MAIN OUTCOME MEASURES Belief that a $500 payment for research participation would impair their own, and others' ability to think carefully about the risks and benefits of a clinical trial. RESULTS Two hundred sixty-one jurors (74.6%) believed that a $500 payment would impair subjects' ability to think carefully about the risks and benefits of research. Ninety-six of 120 (80%) expressed this concern about subjects with a low income ($50,000). In contrast, only 69 (19.7%) of jurors believed that a $500 payment would influence them. Jurors who believed that this payment would influence them reported lower incomes and less education. CONCLUSION Members of the general public share ethical concerns about the influence of payments for research, although they believe that these concerns are more applicable to others than to themselves.

  19. Subjects, Models, Languages, Transformations

    NARCIS (Netherlands)

    Rensink, Arend; Bézivin, J.; Heckel, R.


    Discussions about model-driven approaches tend to be hampered by terminological confusion. This is at least partially caused by a lack of formal precision in defining the basic concepts, including that of "model" and "thing being modelled" - which we call subject in this paper. We propose a minimal

  20. Subjective Duration and Psychophysics (United States)

    Eisler, Hannes


    Three models are proposed to describe the strategy applied by a subject when he is confronted with two successive time intervals and is required to deal with some relation between them, for example, by telling which was the longer by adjusting the second to match the first. (Author)

  1. Barron's SAT subject test

    CERN Document Server

    Jansen, MA, Robert


    Includes one diagnostic test and three complete tests, all questions answered and explained, self-assessment guides, and subject reviews. Also features test strategies, QR codes to short instructional videos, and a detailed appendix with equations, physical constants, and a basic math review.

  2. SLS launched missions concept studies for LUVOIR mission (United States)

    Stahl, H. Philip; Hopkins, Randall C.


    NASA's "Enduring Quests Daring Visions" report calls for an 8- to 16-m Large UV-Optical-IR (LUVOIR) Surveyor mission to enable ultra-high-contrast spectroscopy and coronagraphy. AURA's "From Cosmic Birth to Living Earth" report calls for a 12-m class High-Definition Space Telescope to pursue transformational scientific discoveries. The multi-center ATLAST Team is working to meet these needs. The MSFC Team is examining potential concepts that leverage the advantages of the SLS (Space Launch System). A key challenge is how to affordably get a large telescope into space. The JWST design was severely constrained by the mass and volume capacities of its launch vehicle. This problem is solved by using an SLS Block II-B rocket with its 10-m diameter x 30-m tall fairing and estimated 45 mt payload to SE-L2. Previously, two development study cycles produced a detailed concept called ATLAST-8. Using ATLAST-8 as a point of departure, this paper reports on a new ATLAST-12 concept. ATLAST-12 is a 12-m class segmented aperture LUVOIR with an 8-m class center segment. Thus, ATLAST-8 is now a de-scope option.

  3. Designing an optimal, universal, programmable, and unambiguous discriminator for N unknown qubits (United States)

    Jafarizadeh, M. A.; Mahmoudi, P.; Akhgar, D.; Faizi, E.


    The universal programmable discriminator is a device for discrimination between unknown quantum states. It has two kinds of registers: the program register and the data register. The states that are stored in registers are all unknown. It is assured that the data state is identical with one of the program states with the certain probability. The aim is to optimally identify the state stored in the data register with one of the program states that it is done by discriminating between unknown states of the combined system contains program and data registers. We design an optimal universal unambiguous programmable discriminator that has N qubit systems in the program register, to unambiguously identify the qubit state of data with one of N program qubit states. All unknown qubit states are pure and ND copies of the data state are available. We determine the optimal positive-operator valued measure (POVM) elements in two different ways. First, we find optimal POVMs that maximize the average of the overall success probability of discrimination between N unknown pure states of the combined system. In another way, the problem of discrimination between N unknown pure states of the combined system is reduced to discrimination between N known average mixed states. It is shown that theses two different ways lead to the same results. We show that at least N -1 copies of the data state are necessary for discriminating between N unknown states of the combined system.

  4. Impact of Accurate 30-Day Status on Operative Mortality: Wanted Dead or Alive, Not Unknown. (United States)

    Ring, W Steves; Edgerton, James R; Herbert, Morley; Prince, Syma; Knoff, Cathy; Jenkins, Kristin M; Jessen, Michael E; Hamman, Baron L


    Risk-adjusted operative mortality is the most important quality metric in cardiac surgery for determining The Society of Thoracic Surgeons (STS) Composite Score for star ratings. Accurate 30-day status is required to determine STS operative mortality. The goal of this study was to determine the effect of unknown or missing 30-day status on risk-adjusted operative mortality in a regional STS Adult Cardiac Surgery Database cooperative and demonstrate the ability to correct these deficiencies by matching with an administrative database. STS Adult Cardiac Surgery Database data were submitted by 27 hospitals from five hospital systems to the Texas Quality Initiative (TQI), a regional quality collaborative. TQI data were matched with a regional hospital claims database to resolve unknown 30-day status. The risk-adjusted operative mortality observed-to-expected (O/E) ratio was determined before and after matching to determine the effect of unknown status on the operative mortality O/E. TQI found an excessive (22%) unknown 30-day status for STS isolated coronary artery bypass grafting cases. Matching the TQI data to the administrative claims database reduced the unknowns to 7%. The STS process of imputing unknown 30-day status as alive underestimates the true operative mortality O/E (1.27 before vs 1.30 after match), while excluding unknowns overestimates the operative mortality O/E (1.57 before vs 1.37 after match) for isolated coronary artery bypass grafting. The current STS algorithm of imputing unknown 30-day status as alive and a strategy of excluding cases with unknown 30-day status both result in erroneous calculation of operative mortality and operative mortality O/E. However, external validation by matching with an administrative database can improve the accuracy of clinical databases such as the STS Adult Cardiac Surgery Database. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  5. IMPERA: Integrated Mission Planning for Multi-Robot Systems

    Directory of Open Access Journals (Sweden)

    Daniel Saur


    Full Text Available This paper presents the results of the project IMPERA (Integrated Mission Planning for Distributed Robot Systems. The goal of IMPERA was to realize an extraterrestrial exploration scenario using a heterogeneous multi-robot system. The main challenge was the development of a multi-robot planning and plan execution architecture. The robot team consists of three heterogeneous robots, which have to explore an unknown environment and collect lunar drill samples. The team activities are described using the language ALICA (A Language for Interactive Agents. Furthermore, we use the mission planning system pRoPhEt MAS (Reactive Planning Engine for Multi-Agent Systems to provide an intuitive interface to generate team activities. Therefore, we define the basic skills of our team with ALICA and define the desired goal states by using a logic description. Based on the skills, pRoPhEt MAS creates a valid ALICA plan, which will be executed by the team. The paper describes the basic components for communication, coordinated exploration, perception and object transportation. Finally, we evaluate the planning engine pRoPhEt MAS in the IMPERA scenario. In addition, we present further evaluation of pRoPhEt MAS in more dynamic environments.

  6. 75 FR 9578 - Executive-Led Trade Mission to Colombia and Panama; Change to Mission Dates (United States)


    ... and safety equipment; telecommunications equipment; and travel and tourism services. Mission Scenario... trade mission Referrals from political organizations and any documents containing references to partisan political activities (including political contributions) will be removed from an applicant's submission and...

  7. Linking Knowledge and Skills to Mission Essential Competency-Based Syllabus Development for Distributed Mission Operations

    National Research Council Canada - National Science Library

    Symons, Steve; France, Michael; Bell, Jeffrey; Bennett, Jr, Winston


    ... of Mission Essential Competencies (MECs). MECs are defined as the higher order individual, team, and inter-team competencies that a fully prepared pilot, crew, or flight requires for successful mission completion under adverse conditions...

  8. Composable Mission Framework for Rapid End-to-End Mission Design and Simulation Project (United States)

    National Aeronautics and Space Administration — The innovation proposed here is the Composable Mission Framework (CMF)?a model-based software framework that shall enable seamless continuity of mission design and...

  9. Row Reduced Echelon Form for Solving Fully Fuzzy System with Unknown Coefficients

    Directory of Open Access Journals (Sweden)

    Ghassan Malkawi


    Full Text Available This study proposes a new method for finding a feasible fuzzy solution in positive Fully Fuzzy Linear System (FFLS, where the coefficients are unknown. The fully fuzzy system is transferred to linear system in order to obtain the solution using row reduced echelon form, thereafter; the crisp solution is restricted in obtaining the positive fuzzy solution. The fuzzy solution of FFLS is included crisp intervals, to assign alternative values of unknown entries of fuzzy numbers. To illustrate the proposed method, numerical examples are solved, where the entries of coefficients are unknown in right or left hand side, to demonstrate the contributions in this study.

  10. Learning Innovative Routes for Mobile Robots in Dynamic Partially Unknown Environments

    Directory of Open Access Journals (Sweden)

    Maarja Kruusmaa


    Full Text Available This paper examines path planning strategies in partially unknown dynamic environemnts and introduces an approach to learning innovative routes. The approach is verified against shortest path planning with a distance transform algorithm, local and global replanning and suboptimal route following in unknown, partially unknown, static and dynamic environments. We show that the learned routes are more reliable and when traversed repeatedly the robot?s behaviour becomes more predictable. The test results also suggest that the knowledge about the environemnt but not about the path planning strategy used.

  11. [Subjective cognition in schizophrenia]. (United States)

    Potvin, S; Aubin, G; Stip, E


    Given the extent, magnitude and functional significance of the neurocognitive deficits of schizophrenia, growing attention has been paid recently to patients' self-awareness of their own deficits. Thus far, the literature has shown either that patients fail to recognize their cognitive deficits or that the association between subjective and objective cognition is weak in schizophrenia. The reasons for this lack of consistency remain unexplained but may have to do, among others, with the influence of potential confounding clinical variables and the choice of the scale used to measure self-awareness of cognitive deficits. In the current study, we sought to examine the relationships between subjective and objective cognitive performance in schizophrenia, while controlling for the influence of sociodemographic and psychiatric variables. Eighty-two patients with a schizophrenia-spectrum disorder (DSM-IV criteria) were recruited. Patients' subjective cognitive complaints were evaluated with the Subjective Scale to Investigate Cognition in Schizophrenia (SSTICS), the most frequently used scale to measure self-awareness of cognitive deficits in schizophrenia. Neurocognition was evaluated with working memory, planning and visual learning tasks taken from Cambridge Neuropsychological Tests Automated Battery. The Stroop Color-Word test was also administered. Psychiatric symptoms were evaluated with the Positive and Negative Syndrome Scale and the Calgary Depression Scale for Schizophrenia. The relationships between subjective and objective cognition were evaluated with multivariate hierarchic linear regression analyses, taking into consideration potential confounders such as sociodemographic and psychiatric variables. Finally, a factor analysis of the SSTICS was performed. For the SSTICS total score, the regression analysis produced a model including two predictors, namely visual learning and Stoop interference performance, explaining a moderate portion of the variance

  12. Interaction, transference, and subjectivity

    DEFF Research Database (Denmark)

    Lundgaard Andersen, Linda


    Fieldwork is one of the important methods in educational, social, and organisational research. In fieldwork, the researcher takes residence for a shorter or longer period amongst the subjects and settings to be studied. The aim of this is to study the culture of people: how people seem to make...... sense of their lives and which moral, professional, and ethical values seem to guide their behaviour and attitudes. In fieldwork, the researcher has to balance participation and observation in her attempts at representation. Consequently, the researcher’s academic and life-historical subjectivity...... are important filters for fieldwork. In general, fieldwork can be understood as processes where field reports and field analysis are determined by how the researcher interacts with and experiences the field, the events and informants in it, and how she subsequently develops an ethnography. However, fieldwork...

  13. Writing and the 'Subject'

    DEFF Research Database (Denmark)

    Greve, Charlotte

    /reading subject) manifests itself in the material mark on the page. The study shows how this indexical reference to a ‘subject’ is manipulated and used as a mask through which a writer/painter can perform a certain ‘subject’. Through analyses of the various levels on which the ‘subject’ is represented...... in the early as well as the contemporary avant-garde, it becomes clear that the ‘subject’ is an unstable category that can be exposed to manipulation and play. Handwriting is performing as a signature (as an index), but is at the same time similar to the signature of a subject (an icon) and a verbal construct...

  14. Migrants, mission and theological education

    Directory of Open Access Journals (Sweden)

    Hayes, Stephen


    Full Text Available The Christian Church has faced problems of mission and migrancy from its inception. This paper, however, is limited to southern Africa in the last fifty years, using examples from the Anglican and Orthodox Churches, based mainly on the personal experiences of the author. It begins with the story of a migratory cattle herder in northwestern Namibia who became an evangelist and was trying to plant a church among a nomadic people. There have been other patterns of migration in Southern Africa, including migratory labour, forced removals, refugees, and immigration, both legal and illegal. Theological Education by Extension (TEE, which developed about 40-50 years ago, had the potential to meet some of these needs, though emphasis was often put in the wrong places, so that it did not fulfil the promise of meeting the needs of migrant ministries as well as had been hoped. Materials and resources often had to be improvised, but in many ways much has been achieved.

  15. New Technology Lunar Astronomy Mission (United States)

    Chen, P. C.; Oliversen, R. J.; Barry, R. K.; Romeo, R.; Pitts, R.; Ma, K. B.


    A scientifically productive Moon-based observatory can be established in the near term (3-5 years) by robotic spacecraft. Such a project is affordable even taking into account NASA's currently very tight budget. In fact the estimated cost of a lunar telescope is sufficiently low that it can be financed by private industry, foundations, or wealthy individuals. The key factor is imaginative use of new technologies and new materials. Since the Apollo era, many new areas of space technology have been developed in the US by NASA, the military, academic and industry sectors, ESA, Japan, and others. These include ultralite optics, radiation tolerant detectors, precision telescope drives incorporating high temperature superconductors, smart materials, active optics, dust and thermal control structures, subminiature spectrometers, tiny radio transmitters and receivers, small rockets, innovative fuel saving trajectories, and small precision landers. The combination of these elements makes possible a lunar observatory capable of front line astrophysical research in UV-Vis-IR imaging, spectrometry, and optical interferometry, at a per unit cost comparable to that of Small Explorer (SMEX) class missions. We describe work in progress at NASA GSFC and elsewhere, applications to other space projects, and spinoff benefits to ground-based astronomy, industry, and education.

  16. The LUVOIR Large Mission Concept (United States)

    O'Meara, John; LUVOIR Science and Technology Definition Team


    LUVOIR is one of four large mission concepts for which the NASA Astrophysics Division has commissioned studies by Science and Technology Definition Teams (STDTs) drawn from the astronomical community. We are currently developing two architectures: Architecture A with a 15.1 meter segmented primary mirror, and Architecture B with a 9.2 meter segmented primary mirror. Our focus in this presentation is the Architecture A LUVOIR. LUVOIR will operate at the Sun-Earth L2 point. It will be designed to support a broad range of astrophysics and exoplanet studies. The initial instruments developed for LUVOIR Architecture A include 1) a high-performance optical/NIR coronagraph with imaging and spectroscopic capability, 2) a UV imager and spectrograph with high spectral resolution and multi-object capability, 3) a high-definition wide-field optical/NIR camera, and 4) a high resolution UV/optical spectropolarimeter. LUVOIR will be designed for extreme stability to support unprecedented spatial resolution and coronagraphy. It is intended to be a long-lifetime facility that is both serviceable, upgradable, and primarily driven by guest observer science programs. In this presentation, we will describe the observatory, its instruments, and survey the transformative science LUVOIR can accomplish.

  17. The ADM-Aeolus mission (United States)

    Endemann, Martin


    The Atmospheric Dynamics Mission ADM-Aeolus will make direct measurements of global wind-fields. The aim is to provide global observations of wind profiles with a vertical resolution that will satisfy the requirements of the World Meteorological Organization. The only payload is the Atmospheric Laser Doppler Instrument (ALADIN), a direct detection Doppler lidar operating in the UV. It will determine the wind velocity component normal to the satellite velocity vector. These wind profile measurements will be assimilated into numerical forecasting models to improve the quality of the global three-dimensional wind fields. To make full use of the data, the global wind profile data must be made available to the weather prediction centers in near real time. EADS-Astrium (UK and France) and their subcontractors develop Aeolus and ALADIN. Most subsystems have been completed, and the assembly of the Flight Model is well under way, and proceeding to a launch envisaged in late 2008. Details of ALADIN and several of its subsystems are reported in various papers of this conference.

  18. Peer-to-Peer Planning for Space Mission Control (United States)

    Barreiro, Javier; Jones, Grailing, Jr.; Schaffer, Steve


    Planning and scheduling for space operations entails the development of applications that embed intimate domain knowledge of distinct areas of mission control, while allowing for significant collaboration among them. The separation is useful because of differences in the planning problem, solution methods, and frequencies of replanning that arise in the different disciplines. For example, planning the activities of human spaceflight crews requires some reasoning about all spacecraft resources at timescales of minutes or seconds, and is subject to considerable volatility. Detailed power planning requires managing the complex interplay of power consumption and production, involves very different classes of constraints and preferences, but once plans are generated they are relatively stable.

  19. Evaluating Mission Drift in Microfinance: Lessons for Programs with Social Mission (United States)

    Hishigsuren, Gaamaa


    The article contributes to a better understanding of implications of scaling up on the social mission of microfinance programs. It proposes a methodology to measure the extent, if any, to which a microfinance program with a poverty alleviation mission drifts away from its mission during rapid scaling up and presents findings from a field research…

  20. Evolution of Orion Mission Design for Exploration Mission 1 and 2 (United States)

    Gutkowski, Jeffrey P.; Dawn, Timothy F.; Jedrey, Richard M.


    The evolving mission design and concepts of NASA’s next steps have shaped Orion into the spacecraft that it is today. Since the initial inception of Orion, through the Constellation Program, and now in the Exploration Mission frame-work with the Space Launch System (SLS), each mission design concept and pro-gram goal have left Orion with a set of capabilities that can be utilized in many different mission types. Exploration Missions 1 and 2 (EM-1 and EM-2) have now been at the forefront of the mission design focus for the last several years. During that time, different Design Reference Missions (DRMs) were built, analyzed, and modified to solve or mitigate enterprise level design trades to ensure a viable mission from launch to landing. The resulting DRMs for EM-1 and EM-2 were then expanded into multi-year trajectory scans to characterize vehicle performance as affected by variations in Earth-Moon geometry. This provides Orion’s subsystems with stressing reference trajectories to help design their system. Now that Orion has progressed through the Preliminary and Critical Design Reviews (PDR and CDR), there is a general shift in the focus of mission design from aiding the vehicle design to providing mission specific products needed for pre-flight and real time operations. Some of the mission specific products needed include, large quantities of nominal trajectories for multiple monthly launch periods and abort options at any point in the mission for each valid trajectory in the launch window.

  1. The growth of partnership in mission in global mission history during ...

    African Journals Online (AJOL)


    structures and attitudes which controlled missions for too long and promoted .... dependence, denominational training and, above all, loyalty to their spiritual fathers, now keep ..... Therefore, it involves transformation, vulnerability and risk and is, .... mission structures; it questioned the traditional one-way approach to mission.

  2. Flexible Photovoltaics: Mission Power from the Sun (United States)


    UNCLASSIFIED Flexible Photovoltaics: Mission Power from the Sun NSRDEC Project Officer: Steven Tucker Senior Engineer, EE COMM 508-233-6962 DSN 256...NOV 2009 2. REPORT TYPE 3. DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE Flexible Photovoltaics: Mission Power from the Sun 5a

  3. A mission planner for an autonomous tractor

    DEFF Research Database (Denmark)

    Bochtis, Dionysis; Vougioukas, S.G.; Griepentrog, Hans W.


    In this article, a mission planner of field coverage operations for an autonomous agricultural tractor is presented. Missions for a particular autonomous tractor are defined using an XML (extendible markup language) formatted file that can be uploaded to the tractor through the user interface...

  4. Mellem mission og markedsføring

    DEFF Research Database (Denmark)

    Andreasen, Mette Søgaard


    Kandidatspeciale om forholdet mellem mission og markedsføring i Den Danske Folkekirke i slutningen af 2010'erne. Specialets hypotese er, at mission i Den Danske Folkekirke på mange områder bevæger sig ind i en markedsføringsdiskurs....

  5. Mars Telecom Orbiter mission operations concepts (United States)

    Deutsch, Marie-Jose; Komarek, Tom; Lopez, Saturnino; Townes, Steve; Synnott, Steve; Austin, Richard; Guinn, Joe; Varghese, Phil; Edwards, Bernard; Bondurant, Roy; hide


    The Mars Telecom Orbiter (MTO) relay capability enables next decadal missions at Mars, collecting gigabits of data a day to be relayed back at speeds exceeding 4 Mbps and it facilitates small missions whose limited resources do not permit them to have a direct link to Earth.

  6. Multi-mission telecom analysis tool (United States)

    Hanks, D.; Kordon, M.; Baker, J.


    In the early formulation phase of a mission it is critically important to have fast, easy to use, easy to integrate space vehicle subsystem analysis tools so that engineers can rapidly perform trade studies not only by themselves but in coordination with other subsystem engineers as well. The Multi-Mission Telecom Analysis Tool (MMTAT) is designed for just this purpose.

  7. Radiation Hardness Assurance (RHA) for Small Missions (United States)

    Campola, Michael J.


    Varied mission life and complexity is growing for small spacecraft. Small missions benefit from detailed hazard definition and evaluation as done in the past. Requirements need to flow from the system down to the parts level and aid system level radiation tolerance. RHA is highlighted with increasing COTS usage.

  8. Ockham's Razor Applied: It's Mission Clutter. (United States)

    DeCicco, Emily K.; Allison, Jeanette


    Maintains that assigning schools responsibility for solving societal problems results in mission clutter, the root cause of failure in public schools. Discusses how mission clutter occurred and its dangers, focusing on the loss of critical educational focus, impediment to teacher recruitment and retention, occupational stress, and unfair…

  9. The Ballerina experiment on the Romer mission

    DEFF Research Database (Denmark)

    Brandt, Søren Kristian


    The Romer mission has recently been approved as the next mission within the Danish Small Satellite Program. The scientific payload will consist of two separate experiments, the MONS and the Ballerina payloads. The primary objective of Ballerina is to provide accurate, real-time positions relayed...

  10. Space mission Millimetron for terahertz astronomy

    NARCIS (Netherlands)

    Smirnov, A. V.; Baryshev, A. M.; Pilipenko, S. V.; Myshonkova, N. V.; Bulanov, V. B.; Arkhipov, M. Y.; Vinogradov, I. S.; Likhachev, S. F.; Kardashev, N. S.

    We present an overview of the current status of the space mission Millimetron. Millimetron is a large 10-m cooled space telescope optimized for operation in the submillimeter and far infrared wavelengths. This mission will be able to contribute to the solution of several key problems in

  11. Coatings for the NuSTAR mission

    DEFF Research Database (Denmark)

    Christensen, Finn Erland; Jakobsen, Anders Clemen; Brejnholt, Nicolai


    The NuSTAR mission will be the first mission to carry a hard X-ray(5-80 keV) focusing telescope to orbit. The optics are based on the use of multilayer coated thin slumped glass. Two different material combinations were used for the flight optics, namely W/Si and Pt/C. In this paper we describe...

  12. Solar Power for Future NASA Missions (United States)

    Bailey, Sheila G.; Landis, Geoffrey A.


    An overview of NASA missions and technology development efforts are discussed. Future spacecraft will need higher power, higher voltage, and much lower cost solar arrays to enable a variety of missions. One application driving development of these future arrays is solar electric propulsion.

  13. STS-88 Mission Specialist Krikalev checks equipment (United States)


    STS-88 Mission Specialist Sergei Konstantinovich Krikalev, a Russian cosmonaut, looks over equipment inside a module at the Space Station Processing Facility. Betsy Ahearn, with Boeing, is at his right. Mission STS-88 is targeted for launch on Dec. 3, 1998. It is the first U.S. flight for the assembly of the International Space Station and will carry the Unity connecting module.

  14. Implementing Citizen Science in NASA Missions (United States)

    Day, B. H.


    Citizen science marks the intersection of education, public outreach, and science. Certain technologies, mission constructs, and E/PO plans facilitate participation, directly involving students and the public in the science supporting a mission. The benefits from well-implemented citizen science programs extend significantly beyond enabling extensive data collection. Through such programs, students and the public increase their own understanding of the mission's science and technology, increase their appreciation for the mission's relevance, realize that becoming a scientist or engineer is attainable and interesting, and become advocates among their peers. However, implementing a citizen science program that provides real benefits to both the mission science team and participating citizen scientists presents notable challenges. In this talk, we will look at citizen science programs implemented by a number of past, current, and upcoming missions, including the Stardust, LCROSS, LADEE, and LRO missions. We will discuss the successes and challenges associated with these programs and how the lessons learned can be applied to future missions.

  15. Tank waste remediation system mission analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Acree, C.D.


    The Tank Waste Remediation System Mission Analysis Report identifies the initial states of the system and the desired final states of the system. The Mission Analysis Report identifies target measures of success appropriate to program-level accomplishments. It also identifies program-level requirements and major system boundaries and interfaces.

  16. The Kepler Mission and Eclipsing Binaries (United States)


    exoplanets , differential photometry, eclipsing binaries 1. Introduction The Kepler Mission is NASA’s first mission capable of detecting Earth-size and...a star where liquid water can exist on the surface of a 236 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the

  17. Optimal parking orbits for manned Mars missions (United States)

    Cupples, Michael L.; Nordwall, Jill A.

    This paper summarizes a Mars parking orbit optimization effort. This parking orbit study includes the selection of optimal elliptic Mars parking orbits that meet mission constraints and that include pertinent apsidal misalignment losses. Mars missions examined are for the opportunity years of 2014, 2016, and 2018. For these mission opportunities, it is shown that the optimal parking orbits depend on the year that the mission occurs and are coupled with the outbound, Mars stay, and return phases of the mission. Constraints included in the parking orbit optimization process are periapsis lighting angle (related to a daylight landing requirement), periapsis latitude (related to a landing latitude range requirement) and the vehicle Trans-Earth-Injection stage mass. Also, effects of mission abort requirements on optimal parking orbits are investigated. Off-periapsis maneuvers for Mars orbit capture were found to be cost effective in reducing the mission delta-V for the 2016 abort from Mars capture scenario. The total capture and departure delta-V was `split' between the capture maneuver and the departure maneuver to reduce the 2016 Mars departure delta-V to below the level of the corresponding stage of the 2014 baseline mission. Landing results are provided that show Mars landing site access from the optimal elliptic parking orbits for Mars excursion vehicles with low (0.2) and high (1.3 and 1.6) lift to drag ratio.

  18. Trajectory Design Considerations for Exploration Mission 1 (United States)

    Dawn, Timothy F.; Gutkowski, Jeffrey P.; Batcha, Amelia L.; Williams, Jacob; Pedrotty, Samuel M.


    Exploration Mission 1 (EM-1) will be the first mission to send an uncrewed Orion Multi-Purpose Crew Vehicle (MPCV) to cislunar space in the fall of 2019. EM-1 was originally conceived as a lunar free-return mission, but was later changed to a Distant Retrograde Orbit (DRO) mission as a precursor to the Asteroid Redirect Mission. To understand the required mission performance (i.e., propellant requirement), a series of trajectory optimization runs was conducted using JSC's Copernicus spacecraft trajectory optimization tool. In order for the runs to be done in a timely manner, it was necessary to employ a parallelization approach on a computing cluster using a new trajectory scan tool written in Python. Details of the scan tool are provided and how it is used to perform the scans and post-process the results. Initially, a scan of daily due east launched EM-1 DRO missions in 2018 was made. Valid mission opportunities are ones that do not exceed the useable propellant available to perform the required burns. The initial scan data showed the propellant and delta-V performance patterns for each launch period. As questions were raised from different subsystems (e.g., power, thermal, communications, flight operations, etc.), the mission parameters or data that were of interest to them were added to the scan output data file. The additional data includes: (1) local launch and landing times in relation to sunrise and sunset, (2) length of eclipse periods during the in-space portion of the mission, (3) Earth line of sight from cislunar space, (4) Deep Space Network field of view looking towards cislunar space, and (5) variation of the downrange distance from Earth entry interface to splashdown. Mission design trades can also be performed based on the information that the additional data shows. For example, if the landing is in darkness, but the recovery operations team desires a landing in daylight, then an analysis is performed to determine how to change the mission design

  19. Range-based underwater vehicle localization in the presence of unknown ocean currents: Theory and experiments

    Digital Repository Service at National Institute of Oceanography (India)

    Bayat, M.; Crasta, N.; Aguiar, A.P.; Pascoal, A.M.

    This paper addresses the problem of range-based autonomous underwater vehicle (AUV) localization in the presence of unknown ocean currents. In the setup adopted, the AUV is equipped with an attitude and heading reference system, a depth sensor...

  20. Identification of unknown corpses through odontological examination – two case reports

    National Research Council Canada - National Science Library

    Katarzyna Wochna; Anna K. Smędra; Jarosław Berent; Szymon Szustowski


    The presented paper illustrates the significance of dental documentation which played a key role in the process of identification of two unknown male cadavers by means of dental features examination...

  1. Design of a DNA chip for detection of unknown genetically modified organisms (GMOs). (United States)

    Nesvold, Håvard; Kristoffersen, Anja Bråthen; Holst-Jensen, Arne; Berdal, Knut G


    Unknown genetically modified organisms (GMOs) have not undergone a risk evaluation, and hence might pose a danger to health and environment. There are, today, no methods for detecting unknown GMOs. In this paper we propose a novel method intended as a first step in an approach for detecting unknown genetically modified (GM) material in a single plant. A model is designed where biological and combinatorial reduction rules are applied to a set of DNA chip probes containing all possible sequences of uniform length n, creating probes capable of detecting unknown GMOs. The model is theoretically tested for Arabidopsis thaliana Columbia, and the probabilities for detecting inserts and receiving false positives are assessed for various parameters for this organism. From a theoretical standpoint, the model looks very promising but should be tested further in the laboratory. The model and algorithms will be available upon request to the corresponding author.

  2. Robust Control for the Segway with Unknown Control Coefficient and Model Uncertainties. (United States)

    Kim, Byung Woo; Park, Bong Seok


    The Segway, which is a popular vehicle nowadays, is an uncertain nonlinear system and has an unknown time-varying control coefficient. Thus, we should consider the unknown time-varying control coefficient and model uncertainties to design the controller. Motivated by this observation, we propose a robust control for the Segway with unknown control coefficient and model uncertainties. To deal with the time-varying unknown control coefficient, we employ the Nussbaum gain technique. We introduce an auxiliary variable to solve the underactuated problem. Due to the prescribed performance control technique, the proposed controller does not require the adaptive technique, neural network, and fuzzy logic to compensate the uncertainties. Therefore, it can be simple. From the Lyapunov stability theory, we prove that all signals in the closed-loop system are bounded. Finally, we provide the simulation results to demonstrate the effectiveness of the proposed control scheme.

  3. Robust Control for the Segway with Unknown Control Coefficient and Model Uncertainties

    Directory of Open Access Journals (Sweden)

    Byung Woo Kim


    Full Text Available The Segway, which is a popular vehicle nowadays, is an uncertain nonlinear system and has an unknown time-varying control coefficient. Thus, we should consider the unknown time-varying control coefficient and model uncertainties to design the controller. Motivated by this observation, we propose a robust control for the Segway with unknown control coefficient and model uncertainties. To deal with the time-varying unknown control coefficient, we employ the Nussbaum gain technique. We introduce an auxiliary variable to solve the underactuated problem. Due to the prescribed performance control technique, the proposed controller does not require the adaptive technique, neural network, and fuzzy logic to compensate the uncertainties. Therefore, it can be simple. From the Lyapunov stability theory, we prove that all signals in the closed-loop system are bounded. Finally, we provide the simulation results to demonstrate the effectiveness of the proposed control scheme.

  4. Adaptive Projective Synchronization between Two Different Fractional-Order Chaotic Systems with Fully Unknown Parameters

    Directory of Open Access Journals (Sweden)

    Liping Chen


    between the fractional-order chaotic Chen system and the fractional-order chaotic Lü system with unknown parameters is achieved. Theoretical analysis and numerical simulations are presented to demonstrate the validity and feasibility of the proposed method.

  5. Realtime motion planning for a mobile robot in an unknown environment using a neurofuzzy based approach (United States)

    Zheng, Taixiong


    A neuro-fuzzy network based approach for robot motion in an unknown environment was proposed. In order to control the robot motion in an unknown environment, the behavior of the robot was classified into moving to the goal and avoiding obstacles. Then, according to the dynamics of the robot and the behavior character of the robot in an unknown environment, fuzzy control rules were introduced to control the robot motion. At last, a 6-layer neuro-fuzzy network was designed to merge from what the robot sensed to robot motion control. After being trained, the network may be used for robot motion control. Simulation results show that the proposed approach is effective for robot motion control in unknown environment.

  6. WATER TEMPERATURE and Other Data from UNKNOWN from 19630301 to 19650331 (NODC Accession 9500033) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The chorophyll data set was collected from unknown platforms. Data was collected over two year period spanning from March 1, 1963 to March 31, 1965. The data...

  7. Application of the TTC concept to unknown substances found in analysis of foods

    NARCIS (Netherlands)

    Koster, S.; Boobis, A.R.; Cubberley, R.; Hollnagel, H.M.; Richling, E.; Wildemann, T.; Würtzen, G.; Galli, C.L.


    Unknown substances, not previously observed, are frequently detected in foods by quality control laboratories. In many cases, the assessment of these 'new' substances requires additional chemical analysis for their identification prior to assessing risk. This identification procedure can be

  8. ORION: A Supersynchronous Transfer Orbit mission (United States)

    Walters, I. M.; Baker, J. F.; Shurmer, I. M.


    ORION F1 was launched on 29th November 1994 on an Atlas IIA launch vehicle. It was designed, built and delivered in-orbit by Matra Marconi Space Systems Plc and was handed over to ORION Satellite Corporation on 20th January 1995 at its on-station longitude of 37.5 deg W. The mission differed significantly from that of any other geostationary communications satellite in that the Transfer Orbit apogee altitude of 123,507 km was over three times geosynchronous (GEO) altitude and one third of the way to the moon. The SuperSynchronous Transfer Orbit (SSTO) mission is significantly different from the standard Geostationary Transfer Orbit (GTO)mission in a number of ways. This paper discusses the essential features of the mission design through its evolution since 1987 and the details of the highly successful mission itself including a detailed account of the attitude determination achieved using the Galileo Earth and Sun Sensor (ESS).

  9. ORION: A Supersynchronous Transfer Orbit mission (United States)

    Walters, I. M.; Baker, J. F.; Shurmer, I. M.


    ORION F1 was launched on 29th November 1994 on an Atlas IIA launch vehicle. It was designed, built and delivered in-orbit by Matra Marconi Space Systems Plc and was handed over to ORION Satellite Corporation on 20th January 1995 at its on-station longitude of 37.5 deg W. The mission differed significantly from that of any other geostationary communications satellite in that the Transfer Orbit apogee altitude of 123,507 km was over three times geosynchronous (GEO) altitude and one third of the way to the moon. The SuperSynchronous Transfer Orbit (SSTO) mission is significantly different from the standard Geostationary Transfer Orbit (GTO)mission in a number of ways. This paper discusses the essential features of the mission design through its evolution since 1987 and the details of the highly successful mission itself including a detailed account of the attitude determination achieved using the Galileo Earth and Sun Sensor (ESS).

  10. The Economics of NASA Mission Cost Reserves (United States)

    Whitley, Sally; Shinn, Stephen


    Increases in NASA mission costs have led to analysis of the causes and magnitude of historical mission overruns as well as mitigation and prevention attempts. This paper hypothesizes that one cause is that the availability of reserves may reduce incentives to control costs. We draw a comparison to the insurance concept of moral hazard, and we use actuarial techniques to better understand the increase in mission costs due to the availability of reserves. NASA's CADRe database provided the data against which we tested our hypothesis and discovered that there is correlation between the amount of available reserves and project overruns, particularly for mission hardware cost increases. We address the question of how to prevent reserves from increasing mission spending without increasing cost risk to projects.

  11. Super-Resolution of Complex Exponentials from Modulations with Unknown Waveforms


    Yang, Dehui; Tang, Gongguo; Wakin, Michael B.


    Super-resolution is generally referred to as the task of recovering fine details from coarse information. Motivated by applications such as single-molecule imaging, radar imaging, etc., we consider parameter estimation of complex exponentials from their modulations with unknown waveforms, allowing for non-stationary blind super-resolution. This problem, however, is ill-posed since both the parameters associated with the complex exponentials and the modulating waveforms are unknown. To allevia...

  12. Unknown sequence amplification: Application to in vitro genome walking in Chlamydia trachomatis L2

    Energy Technology Data Exchange (ETDEWEB)

    Copley, C.G.; Boot, C.; Bundell, K.; McPheat, W.L. (ICI Diagnostics, Cheshire (United Kingdom))


    A recently described technique, Chemical Genetics' unknown sequence amplification method, which requires only one specific oligonucleotide, has broadened the applicability of the polymerase chain reaction to DNA of unknown sequence. The authors have adapted this technique to the study of the genome of Chlamydia trachomatis, an obligate intracellular bacterium, and describe modifications that significantly improve the utility of this approach. These techniques allow for rapid genomic analysis entirely in vitro, using DNA of limited quantity of purity.

  13. Pattern Recognition Algorithm for High-Sensitivity Odorant Detection in Unknown Environments (United States)

    Duong, Tuan A.


    In a realistic odorant detection application environment, the collected sensory data is a mix of unknown chemicals with unknown concentrations and noise. The identification of the odorants among these mixtures is a challenge in data recognition. In addition, deriving their individual concentrations in the mix is also a challenge. A deterministic analytical model was developed to accurately identify odorants and calculate their concentrations in a mixture with noisy data.

  14. Average Consensus Problems in Networks of Agents with Fixed and Switching Topology and Unknown Control Direction

    Directory of Open Access Journals (Sweden)

    Caixian Sun


    Full Text Available This paper is devoted to the average consensus problems in directed networks of agents with unknown control direction. In this paper, by using Nussbaum function techniques and Laplacian matrix, novel average consensus protocols are designed for multiagent systems with unknown control direction in the cases of directed networks with fixed and switching topology. In the case of switching topology, the disagreement vector is utilized. Finally, simulation is provided to demonstrate the effectiveness of our results.

  15. Concepts For An EO Land Convoy Mission (United States)

    Cutter, M. A.; Eves, S.; Remedios, J.; Humpage, N.; Hall, D.; Regan, A.


    ESA are undertaking three studies investigating possible synergistic satellite missions flying in formation with the operational Copernicus Sentinel missions and/or the METOP satellites. These three studies are focussed on:- a) ocean and ice b) land c) atmosphere Surrey Satellite Technology Ltd (SSTL), the University of Leicester and Astrium Ltd are undertaking the second of these studies into the synergetic observation by missions flying in formation with European operational missions, focusing on the land theme. The aim of the study is to identify and develop, (through systematic analysis), potential innovative Earth science objectives and novel applications and services that could be made possible by flying additional satellites, (possibly of small-class type), in constellation or formation with one or more already deployed or firmly planned European operational missions, with an emphasis on the Sentinel missions, but without excluding other possibilities. In the long-term, the project aims at stimulating the development of novel, (smaller), mission concepts in Europe that may exploit new and existing European operational capacity in order to address in a cost effective manner new scientific objectives and applications. One possible route of exploitation would be via the proposed Small Mission Initiative (SMI) that may be initiated under the ESA Earth Explorer Observation Programme (EOEP). The following ESA science priority areas have been highlighted during the study [1]:- - The water cycle - The carbon cycle - Terrestrial ecosystems - Biodiversity - Land use and land use cover - Human population dynamics The study team have identified the science gaps that might be addressed by a "convoy" mission flying with the Copernicus Sentinel satellites, identified the candidate mission concepts and provided recommendations regarding the most promising concepts from a list of candidates. These recommendations provided the basis of a selection process performed by ESA

  16. Subject Sensitive Invariantism: In Memoriam

    NARCIS (Netherlands)

    Blaauw, M.J.


    Subject sensitive invariantism is the view that whether a subject knows depends on what is at stake for that subject: the truth-value of a knowledge-attribution is sensitive to the subject's practical interests. I argue that subject sensitive invariantism cannot accept a very plausible principle for

  17. Adaptive Fault-Tolerant Control of Uncertain Nonlinear Large-Scale Systems With Unknown Dead Zone. (United States)

    Chen, Mou; Tao, Gang


    In this paper, an adaptive neural fault-tolerant control scheme is proposed and analyzed for a class of uncertain nonlinear large-scale systems with unknown dead zone and external disturbances. To tackle the unknown nonlinear interaction functions in the large-scale system, the radial basis function neural network (RBFNN) is employed to approximate them. To further handle the unknown approximation errors and the effects of the unknown dead zone and external disturbances, integrated as the compounded disturbances, the corresponding disturbance observers are developed for their estimations. Based on the outputs of the RBFNN and the disturbance observer, the adaptive neural fault-tolerant control scheme is designed for uncertain nonlinear large-scale systems by using a decentralized backstepping technique. The closed-loop stability of the adaptive control system is rigorously proved via Lyapunov analysis and the satisfactory tracking performance is achieved under the integrated effects of unknown dead zone, actuator fault, and unknown external disturbances. Simulation results of a mass-spring-damper system are given to illustrate the effectiveness of the proposed adaptive neural fault-tolerant control scheme for uncertain nonlinear large-scale systems.

  18. Evaluation of the prevalence and clinical impact of toxocariasis in patients with eosinophilia of unknown origin. (United States)

    Kim, Hong-Beum; Seo, Jun-Won; Lee, Jun-Hyung; Choi, Byung-Seok; Park, Sang-Gon


    Eosinophilia has numerous diverse causes, and in many patients, it is not possible to establish the cause of eosinophilia. Recently, toxocariasis was introduced as one cause of eosinophilia. The aims of this study were to evaluate the prevalence of toxocariasis and the clinical impact of albendazole treatment for toxocariasis in patients suspected of eosinophilia of unknown origin. We performed a retrospective chart review. After evaluation of cause of eosinophilia, the patients suspected of eosinophilia of unknown origin performed immunoglobulin G antibody specific assay for the Toxocara canis larval antigen by enzyme-linked immunosorbent assay. This study evaluated 113 patients, 69 patients (61%) were suspected of eosinophilia of unknown origin. Among these 69 patients, the frequency of T. canis infection was very high (45 patients, 65.2%), and albendazole treatment for 45 eosinophilia with toxocariasis was highly effective for a cure of eosinophilia than no albendazole group regardless of steroid (82.3%, p = 0.007). Furthermore, among the nonsteroid treated small group (19 patients), albendazole treatment for eosinophilia were more effective than no albendazole group, too (83.3% vs. 28.6 %, p = 0.045). The prevalence of toxocariasis was high among patients suspected of eosinophilia of unknown origin; therefore, evaluation for T. canis infection is recommended for patients with eosinophilia of unknown origin. Furthermore, for patients suspected of eosinophilia of unknown origin who have positive results for T. canis, albendazole treatment may be considered a valuable treatment option.

  19. Cost considerations for interstellar missions (United States)

    Andrews, Dana G.

    This paper examines the technical and economic feasibility of interstellar exploration. Three candidate interstellar propulsion systems are evaluated with respect to technical viability and compared on an estimated cost basis. Two of the systems, the laser-propelled lightsail (LPL) and the particle-beam propelled magsail (PBPM), appear to be technically feasible and capable supporting one-way probes to nearby star systems within the lifetime of the principal investigators, if enough energy is available. The third propulsion system, the antimatter rocket, requires additional proof of concept demonstrations before its feasibility can be evaluated. Computer simulations of the acceleration and deceleration interactions of LPL and PBPM were completed and spacecraft configurations optimized for minimum energy usage are noted. The optimum LPL transfers about ten percent of the laser beam energy into kinetic energy of the spacecraft while the optimum PBPM transfers about thirty percent. Since particle beam generators are roughly twice as energy efficient as large lasers, the PBPM propulsion system requires roughly one-sixth the busbar electrical energy a LPL system would require to launch an identical payload. The total beam energy requirement for an interstellar probe mission is roughly 10 20 joules, which would require the complete fissioning of one thousand tons of Uranium assuming thirty-five percent powerplant efficiency. This is roughly equivalent to a recurring cost per flight of 3.0 Billion dollars in reactor grade enriched uranium using today's prices. Therefore, interstellar flight is an expensive proposition, but not unaffordable, if the nonrecurring costs of building the powerplant can be minimized.

  20. Astronaut Clothing for Exploration Missions (United States)

    Poritz, Darwin H.; Orndoff, Evelyne; Kaspranskiy, Rustem R.; Schesinger, Thilini; Byrne, Vicky


    Astronaut clothes for exploration missions beyond low Earth orbit need to satisfy several challenges not met by the currently-used mostly-cotton clothing. A laundering system is not expected to be available, and thus soiled garments must be trashed. Jettisoning waste does not seem feasible at this time. The cabin oxygen concentration is expected to be higher than standard, and thus fabrics must better resist ignition and burning. Fabrics need to be identified that reduce logistical mass, that can be worn longer before disposal, that are at least as comfortable as cotton, and that resist ignition or that char immediately after ignition. Human factors and psychology indicate that crew well-being and morale require a variety of colors and styles to accommodate personal identity and preferences. Over the past four years, the Logistics Reduction Project under NASA's Advanced Exploration Systems Program has sponsored the Advanced Clothing System Task to conduct several ground studies and one ISS study. These studies have evaluated length of wear and personal preferences of commercially-available exercise- and routine-wear garments made from several fabrics (cotton, polyester, Merino wool, and modacrylic), woven and knitted. Note that Merino wool and modacrylic char like cotton in ambient air, while polyester unacceptably melts. This paper focuses on the two components of an International Space Station study, onboard and on the ground, with astronauts and cosmonauts. Fabrics were randomized to participants. Length of wear was assessed by statistical survival analysis, and preference by exact binomial confidence limits. Merino wool and modacrylic t-shirts were worn longer on average than polyester t-shirts. Interestingly, self-assessed preferences were inconsistent with length-of-wear behavior, as polyester was preferred to Merino wool and modacrylic.