WorldWideScience

Sample records for subject systems analysis

  1. The Subject Analysis of Payment Systems Characteristics

    OpenAIRE

    Korobeynikova Olga Mikhaylovna

    2015-01-01

    The article deals with the analysis of payment systems aimed at identifying the categorical terminological apparatus, proving their specific features and revealing the impact of payment systems on the state of money turnover. On the basis of the subject analysis, the author formulates the definitions of a payment system (characterized by increasing speed of effecting payments, by the reduction of costs, by high degree of payments convenience for subjects of transactions, by security of paymen...

  2. The Subject Analysis of Payment Systems Characteristics

    Directory of Open Access Journals (Sweden)

    Korobeynikova Olga Mikhaylovna

    2015-09-01

    Full Text Available The article deals with the analysis of payment systems aimed at identifying the categorical terminological apparatus, proving their specific features and revealing the impact of payment systems on the state of money turnover. On the basis of the subject analysis, the author formulates the definitions of a payment system (characterized by increasing speed of effecting payments, by the reduction of costs, by high degree of payments convenience for subjects of transactions, by security of payments, by acceptable level of risks and by social efficiency, a national payment system, and a local payment system (characterized by the growth of economic and social efficiency of systems participants, by the process of money turnover optimization on the basis of saving transaction costs and increasing speed of money flows within the local payment systems. According to the economic levels, the payment systems are divided to macrosystems (national payment systems, mezosystems (payment systems localized on the operational and territorial basis, microsystems (payments by individual economic subjects. The establishment of qualitative features of payment systems, which is a basis of the author’s terminological interpretation, gave a possibility to reveal the cause-effect relations of payment systems influence on the state of money turnover in the involved subjects, and on the economy as a whole. The result of the present research consists in revealing the payment systems influence on the state of money turnover which is significant: at the state and regional level – in the optimization of budget and inter-budgetary relations, in acceleration of the money turnover, in deceleration of the money supply and inflation rate, in reduced need in money emission; at the level of economic entities – in accelerating the money turnover and accounts receivable, in the reduction of debit and credit loans, in the growth of profit (turnover; at the household level – in

  3. [Measuring facial paralysis using the three-dimensional dynamic quantitative analysis system of facial motion: correlation with subjective grading systems].

    Science.gov (United States)

    Zhao, Y; Feng, G D; Wu, H Y; Zhuang, Y; Gao, Z Q

    2016-07-07

    The aim of this study was to measure the facial motion of patients with facial paralysis using a three-dimensional dynamic quantitative analysis system of facial motion (3D ASFM) and analyze its correlation with subjective grading systems. We included 30 healthy volunteers and 50 patients with unilateral facial paralysis. After placing landmarks on the faces, the facial motions of the patients were measured using the 3D ASFM. The regional symmetry ratios(SRs) and gross scores of different parameters were calculated. Then a comparison with four subjective grading systems(House-Brackmann, Sunnybrook, Facial Nerve Grading System 2.0, Fisch) was performed. The entire test could be completed within five minutes. The normal range of healthy volunteers were obtained, the gross score of which was 91.9±1.5. The SRs of the maximal moving distance(MMD) were most strongly correlated with regional subjective grading systems, followed by the SRs of the maximal moving velocity (MMV). The SRs of the maximal moving acceleration (MMA) were either poorly correlated or uncorrelated with the subjective grading systems. Moreover, the Spearman coefficients with four subjective grading systems were -0.630(House-Brackmann), -0.728(Facial Nerve Grading System 2.0), 0.697(Sunnybrook), and 0.617(Fisch)respectively(Pfacial paralysis. It not only overcomes the shortcomings of conventional subjective grading systems, but also correlates well with them.

  4. Stochastic analysis model for vehicle-track coupled systems subject to earthquakes and track random irregularities

    Science.gov (United States)

    Xu, Lei; Zhai, Wanming

    2017-10-01

    This paper devotes to develop a computational model for stochastic analysis and reliability assessment of vehicle-track systems subject to earthquakes and track random irregularities. In this model, the earthquake is expressed as non-stationary random process simulated by spectral representation and random function, and the track random irregularities with ergodic properties on amplitudes, wavelengths and probabilities are characterized by a track irregularity probabilistic model, and then the number theoretical method (NTM) is applied to effectively select representative samples of earthquakes and track random irregularities. Furthermore, a vehicle-track coupled model is presented to obtain the dynamic responses of vehicle-track systems due to the earthquakes and track random irregularities at time-domain, and the probability density evolution method (PDEM) is introduced to describe the evolutionary process of probability from excitation input to response output by assuming the vehicle-track system as a probabilistic conservative system, which lays the foundation on reliability assessment of vehicle-track systems. The effectiveness of the proposed model is validated by comparing to the results of Monte-Carlo method from statistical viewpoint. As an illustrative example, the random vibrations of a high-speed railway vehicle running on the track slabs excited by lateral seismic waves and track random irregularities are analyzed, from which some significant conclusions can be drawn, e.g., track irregularities will additionally promote the dynamic influence of earthquakes especially on maximum values and dispersion degree of responses; the characteristic frequencies or frequency ranges respectively governed by earthquakes and track random irregularities are greatly different, moreover, the lateral seismic waves will dominate or even change the characteristic frequencies of system responses of some lateral dynamic indices at low frequency.

  5. Status and subjects of thermal-hydraulic analysis for next-generation LWRs with passive safety systems

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The present status and subjects on thermal-hydraulic analysis for next-generation light water reactors (LWRs) with passive safety systems were summarized based on survey results and discussion by subcommittee on improvement of reactor thermal-hydraulic analysis codes under nuclear code committee in Japan Atomic Energy Research Institute. This survey was performed to promote the research of improvement of reactor thermal-hydraulic analysis codes in future. In the first part of this report, the status and subjects on system analysis and those on evaluation of passive safety system performance are summarized for various types of reactor proposed before. In the second part, the status and subjects on multidimensional two-phase flow analysis are reviewed, since the multidimensional analysis was recognized as one of most important subjects through the investigation in the first part. Besides, databases for bubbly flow and annular dispersed flow were explored, those are needed to assess and verify each multidimensional analytical method. The contents in this report are the forefront of thermal-hydraulic analysis for LWRs and those include current findings for the development of multidimensional two-phase flow analytical method. Thus, we expect that the contents can offer various useful information against the improvement of reactor thermal-hydraulic analysis codes in future. (author)

  6. Biomechanical analysis of running in weightlessness on a treadmill equipped with a subject loading system.

    Science.gov (United States)

    Gosseye, Thierry P; Willems, Patrick A; Heglund, Norman C

    2010-11-01

    One countermeasure used during long-duration spaceflight to maintain bone and muscle mass is a treadmill equipped with a subject loading system (SLS) that simulates gravity. To date, little is known about the biomechanics of running in weightlessness on such a treadmill-SLS system. We have designed an instrumented treadmill/force plate to compare the biomechanics of running in weightlessness to running on Earth. Gravity was simulated by two pneumatic pistons pulling downward on a subject's harness, with a force approximately equal to body weight on Earth. Four transducers, mounted under the treadmill, measured the three components of the reaction force exerted by the tread belt under the foot. A high-speed video camera recorded the movements of limb segments while the electromyography of the four lower limb muscles was registered. Experiments in weightlessness were conducted during the European Space Agency parabolic flight campaigns. Control experiments were performed on the same subjects on Earth. When running on the treadmill with an SLS, the bouncing mechanism of running is preserved. Depending on the speed of progression, the ground reaction forces, contact and aerial times, muscular work and bone stress differed by a maximum of ± 5-15% during running on the treadmill with an SLS, as compared to that on Earth. The movements of the lower limb segments and the EMG patterns of the lower limb muscles were also comparable. Thus, the biomechanics of running on Earth can reasonably be duplicated in weightlessness using a treadmill with an SLS that generates a pull-down force close to body weight on Earth.

  7. Fracture mechanics analysis for a mooring system subjected to tension and out-of-plane bending

    Science.gov (United States)

    Xue, X.; Chen, N.-Z.

    2017-12-01

    A fracture mechanics analysis for the mooring system of a semi-submersible accounting for out-of-plane bending (OPB) is presented in this paper. Stress ranges acting on the mooring chain links are calculated based on tension and OPB of mooring chain links induced by motions of wave frequency (WF) and low frequency (LF). The narrow-banded method is used for predicting the combined mooring loading process. Initial cracks are assumed to propagate from surfaces of chain links and stress intensity factors are then calculated in terms of stress ranges determined by a finite element analysis. The influence of the OPB on the remaining service life of mooring chain links is investigated and the results show that the remaining service life of mooring chain links connecting to fairleads is significantly reduced due to the OPB effects.

  8. Experimental analysis of CO₂ emissions from agricultural soils subjected to five different tillage systems in Lithuania.

    Science.gov (United States)

    Buragienė, Sidona; Šarauskis, Egidijus; Romaneckas, Kęstutis; Sasnauskienė, Jurgita; Masilionytė, Laura; Kriaučiūnienė, Zita

    2015-05-01

    Intensive agricultural production strongly influences the global processes that determine climate change. Thus, tillage can play a very important role in climate change. The intensity of soil carbon dioxide (CO₂) emissions, which contribute to the greenhouse effect, can vary depending on the following factors: the tillage system used, meteorological conditions (which vary in different regions of the world), soil properties, plant residue characteristics and other factors. The main purpose of this research was to analyse and assess the effects of autumn tillage systems with different intensities on CO₂ emissions from soils during different seasons and under the climatic conditions of Central Lithuania. The research was conducted at the Experimental Station of Aleksandras Stulginskis University from 2009 to 2012; and in 2014. The soils at the experimental site were classified as Eutric Endogleyic Planosol (Drainic). The investigations were conducted using five tillage systems with different intensities, typical of the Baltic Region. Deep conventional ploughing was performed at a depth of 230-250 mm, shallow ploughing was conducted at a depth of 120-150 mm, deep loosening was conducted at depths of 250-270 mm, and shallow loosening was conducted at depths of 120-150 mm. The fifth system was a no-tillage system. Overall, autumn tillage resulted in greater CO₂ emissions from the soil over both short- and long-term periods under the climatic conditions of Central Lithuania, regardless of the tillage system applied. The highest soil CO₂ emissions were observed for the conventional deep ploughing tillage system, and the lowest emissions were observed for the no-tillage system. The meteorological conditions greatly influenced the CO₂ emissions from the soil during the spring. Soil CO₂ emissions were enhanced as precipitation and the air and soil temperatures increased. Long-term investigations regarding the dynamics of CO₂ emissions from soils during the maize

  9. Numerical Analysis of a Train-Bridge System Subjected to Earthquake and Running Safety Evaluation of Moving Train

    Directory of Open Access Journals (Sweden)

    Xun Yang

    2016-01-01

    Full Text Available This paper investigates the dynamic response of a train-bridge system subjected to earthquakes, and the running safety indices of the train on the bridge under earthquake are studied. Taking a long span cable-stayed bridge across the Huangpu River as an example, a full three-dimensional finite element model of the train-bridge system was established, in which the soil-bridge and rail-train interactions were considered. Parallel computing based on contact balance was utilized to deal with this large-scale numerical simulation problem. The dynamic nonlinear analysis was performed on a Hummingbird supercomputer using the finite element code LS-DYNA 971. The results show that the acceleration responses of the train subjected to an earthquake are much greater than the ones without earthquake input, and the running safety of a moving train is affected by both the earthquake intensity and the running speed of the train. The running safety of the moving train can be evaluated by the threshold curve between earthquake intensity and train speed. The proposed modeling strategies and the simulated results can give a reference prediction of the dynamic behaviour of the train-bridge subjected to an earthquake.

  10. Modeling and Analysis Tools for Linear and Nonlinear Mechanical Systems Subjected to Extreme Impulsive Loading

    Science.gov (United States)

    2015-03-23

    and seismic motion analysis [3]. In many military and civil applications, nonlinear mechanical wave prop- agation occurs through structural...ture are prepared and performed by using MATLAB . The proposed force iden- tification method is also implemented and studied by using MATLAB and...methods is listed in Table. 3. A Dell desktop with a Intel Core Quad CPU is used for all simulations. The parallel computing toolbox in MATLAB is used to

  11. Picture Exchange Communication System with Individuals with Developmental Disabilities: A Meta-Analysis of Single Subject Studies

    Science.gov (United States)

    Hart, Stephanie L.; Banda, Devender R.

    2010-01-01

    Picture Exchange Communication System (PECS) is a picture-based communication strategy used to teach communication skills to persons with developmental disabilities including autism. This article systematically reviews 13 published single-subject studies to examine the effectiveness of PECS, the effects of PECS on speech and problem behaviors,…

  12. Time-course analysis of stretch reflexes in hemiparetic subjects using an on-line spasticity measurement system.

    Science.gov (United States)

    Ju, M S; Chen, J J; Lee, H M; Lin, T S; Lin, C C; Huang, Y Z

    2000-02-01

    Spasticity after a stroke is usually assessed in a score form by subjectively determining the resistance of a joint to an externally imposed passive movement. This work presents a spasticity measurement system for on-line quantifying the stretch reflex of paretic limbs. Four different constant stretch velocities in a ramp-and-hold mode are used to elicit the stretch reflex of the elbow joint in spastic subjects. The subjects are tested at supine position with the upper limb stretched towards the ground, in contrast with the horizontally stretched movement used in other studies. By subtracting the baseline torque, reflex torque measured at a selected low stretch velocity of 5 deg/sec, the influence of gravity torque and inertial in vertical stretching mode can be minimized. The averaged speed-dependent reflex torque (ASRT), defined as the measured torque deviated from the baseline torque, is used for quantifying the spastic hypertonia. Four subjects having incurred cerebrovascular accident (CVA) are recruited for time-course study in which the measurements are taken at 72 hours, one week, one month, three months, and six months after onset of stroke. During the development of spasticity, the changes of ASRT and velocity sensitivity of ASRT of the involved and the intact elbow joints are discussed.

  13. Dynamic lighting systems in psychogeriatric care facilities in The Netherlands: a quantitative and qualitative analysis of the subjective responses of stakeholders and technology.

    NARCIS (Netherlands)

    M.B.C. Aries; J. van Hoof; J. Straathof; M.P.J. Aarts

    2014-01-01

    Aarts, M.P.J., Aries, M.B.C., Straathof, J., van Hoof, J. (2014) Dynamic lighting systems in psychogeriatric care facilities in The Netherlands: a quantitative and qualitative analysis of the subjective responses of stakeholders and technology. Indoor and Built Environment doi:

  14. Stochastic Analysis of the Efficiency of a Wireless Power Transfer System Subject to Antenna Variability and Position Uncertainties.

    Science.gov (United States)

    Rossi, Marco; Stockman, Gert-Jan; Rogier, Hendrik; Vande Ginste, Dries

    2016-07-19

    The efficiency of a wireless power transfer (WPT) system in the radiative near-field is inevitably affected by the variability in the design parameters of the deployed antennas and by uncertainties in their mutual position. Therefore, we propose a stochastic analysis that combines the generalized polynomial chaos (gPC) theory with an efficient model for the interaction between devices in the radiative near-field. This framework enables us to investigate the impact of random effects on the power transfer efficiency (PTE) of a WPT system. More specifically, the WPT system under study consists of a transmitting horn antenna and a receiving textile antenna operating in the Industrial, Scientific and Medical (ISM) band at 2.45 GHz. First, we model the impact of the textile antenna's variability on the WPT system. Next, we include the position uncertainties of the antennas in the analysis in order to quantify the overall variations in the PTE. The analysis is carried out by means of polynomial-chaos-based macromodels, whereas a Monte Carlo simulation validates the complete technique. It is shown that the proposed approach is very accurate, more flexible and more efficient than a straightforward Monte Carlo analysis, with demonstrated speedup factors up to 2500.

  15. Stochastic Analysis of the Efficiency of a Wireless Power Transfer System Subject to Antenna Variability and Position Uncertainties

    Directory of Open Access Journals (Sweden)

    Marco Rossi

    2016-07-01

    Full Text Available The efficiency of a wireless power transfer (WPT system in the radiative near-field is inevitably affected by the variability in the design parameters of the deployed antennas and by uncertainties in their mutual position. Therefore, we propose a stochastic analysis that combines the generalized polynomial chaos (gPC theory with an efficient model for the interaction between devices in the radiative near-field. This framework enables us to investigate the impact of random effects on the power transfer efficiency (PTE of a WPT system. More specifically, the WPT system under study consists of a transmitting horn antenna and a receiving textile antenna operating in the Industrial, Scientific and Medical (ISM band at 2.45 GHz. First, we model the impact of the textile antenna’s variability on the WPT system. Next, we include the position uncertainties of the antennas in the analysis in order to quantify the overall variations in the PTE. The analysis is carried out by means of polynomial-chaos-based macromodels, whereas a Monte Carlo simulation validates the complete technique. It is shown that the proposed approach is very accurate, more flexible and more efficient than a straightforward Monte Carlo analysis, with demonstrated speedup factors up to 2500.

  16. Reliability of Human Subject - Artificial System Interactions

    Directory of Open Access Journals (Sweden)

    M. Novák

    2002-01-01

    Full Text Available Main problems related to reliability of interaction between human subject and artificial system (namely of the transportation character are discussed. The paper consists of three mayor parts:The first one is devoted to the theoretical backgrounds of the problem from the both theory of system reliability and neurology/psychology views.Second part presents the discussion of relevant methodologies of the classification and prediction of the reliability decline. The methodology based on EEG pattern analysis is chosen as the appropriate one for the presented task. The key phenomenon of "micro-sleep" is discussed in detail.The last part presents some latest experimental results in context of presented knowledge. Proposals for the future studies are presented at the end of the presented article. The special interest should be devoted to the analysis and in-time prediction of fatal attention decreases and to the design and construction of the respective on-board applicable warning system.

  17. Comparative analysis of viral shedding in pediatric and adult subjects with central nervous system-associated enterovirus infections from 2013 to 2015 in Switzerland.

    Science.gov (United States)

    Cordey, S; Schibler, M; L'Huillier, A G; Wagner, N; Gonçalves, A R; Ambrosioni, J; Asner, S; Turin, L; Posfay-Barbe, K M; Kaiser, L

    2017-04-01

    Several enterovirus (EV) genotypes can result in aseptic meningitis, but their routes of access to the central nervous system remain to be elucidated and may differ between the pediatric and adult populations. To assess the pattern of viral shedding in pediatric and adult subjects with acute EV meningitis and to generate EV surveillance data for Switzerland. All pediatric and adult subjects admitted to the University Hospitals of Geneva with a diagnosis of EV meningitis between 2013 and 2015 were enrolled. A quantitative EV real-time reverse transcriptase (rRT)-PCR was performed on the cerebrospinal fluid (CSF), blood, stool, urine and respiratory specimens to assess viral shedding and provide a comparative analysis of pediatric and adult populations. EV genotyping was systematically performed. EV positivity rates differed significantly between pediatric and adult subjects; 62.5% of pediatric cases (no adult case) were EV-positive in stool and blood for subjects for whom these samples were all collected. Similarly, the EV viral load in blood was significantly higher in pediatric subjects. Blood C-reactive protein levels were lower and the number of leucocytes/mm3 in the CSF were higher in non-viremic than in viremic pediatric subjects, respectively. A greater diversity of EV genotypes was observed in pediatric cases, with a predominance of echovirus 30 in children ≥3 years old and adults. In contrast to adults, EV-disseminated infections are predominant in pediatric subjects and show different patterns of EV viral shedding. This observation may be useful for clinicians and contribute to modify current practices of patient care. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  18. Same Noses, Different Nasalance Scores: Data from Normal Subjects and Cleft Palate Speakers for Three Systems for Nasalance Analysis

    Science.gov (United States)

    Bressmann, Tim; Klaiman, Paula; Fischbach, Simone

    2006-01-01

    Nasalance scores from the Nasometer, the NasalView and the OroNasal System were compared. The data was collected from 50 normal participants and 19 hypernasal patients with cleft palate. The Nasometer had the lowest nasalance scores for the non-nasal Zoo Passage and that the OroNasal System had the lowest nasalance scores for the Nasal Sentences.…

  19. Experimental analysis of CO{sub 2} emissions from agricultural soils subjected to five different tillage systems in Lithuania

    Energy Technology Data Exchange (ETDEWEB)

    Buragienė, Sidona [Institute of Agricultural Engineering and Safety, Aleksandras Stulginskis University, Studentu str. 15A, LT-53361 Akademija, Kaunas distr. (Lithuania); Šarauskis, Egidijus, E-mail: egidijus.sarauskis@asu.lt [Institute of Agricultural Engineering and Safety, Aleksandras Stulginskis University, Studentu str. 15A, LT-53361 Akademija, Kaunas distr. (Lithuania); Romaneckas, Kęstutis, E-mail: kestas.romaneckas@asu.lt [Institute of Agroecosystems and Soil Science, Aleksandras Stulginskis University, Studentu str. 11, Akademija LT-53361, Kaunas dist. (Lithuania); Sasnauskienė, Jurgita, E-mail: jurgita.sasnauskiene@asu.lt [Institute of Environment and Ecology, Aleksandras Stulginskis University, Studentu str. 11, Akademija LT-53361, Kaunas dist. (Lithuania); Masilionytė, Laura, E-mail: laura.masilionyte@gmail.com [Joniskelis Experimental Station, Lithuanian Research Centre for Agriculture and Forestry, Joniskelis, LT-39301 Pasvalys distr. (Lithuania); Kriaučiūnienė, Zita, E-mail: zita.kriauciuniene@asu.lt [Experimental Station, Aleksandras Stulginskis University, Rapsu str. 7, LT-53363 Noreikiskes, Kaunas distr. (Lithuania)

    2015-05-01

    Intensive agricultural production strongly influences the global processes that determine climate change. Thus, tillage can play a very important role in climate change. The intensity of soil carbon dioxide (CO{sub 2}) emissions, which contribute to the greenhouse effect, can vary depending on the following factors: the tillage system used, meteorological conditions (which vary in different regions of the world), soil properties, plant residue characteristics and other factors. The main purpose of this research was to analyse and assess the effects of autumn tillage systems with different intensities on CO{sub 2} emissions from soils during different seasons and under the climatic conditions of Central Lithuania. The research was conducted at the Experimental Station of Aleksandras Stulginskis University from 2009 to2012; and in 2014. The soils at the experimental site were classified as Eutric Endogleyic Planosol (Drainic). The investigations were conducted using five tillage systems with different intensities, typical of the Baltic Region. Deep conventional ploughing was performed at a depth of 230–250 mm, shallow ploughing was conducted at a depth of 120–150 mm, deep loosening was conducted at depths of 250–270 mm, and shallow loosening was conducted at depths of 120–150 mm. The fifth system was a no-tillage system. Overall, autumn tillage resulted in greater CO{sub 2} emissions from the soil over both short- and long-term periods under the climatic conditions of Central Lithuania, regardless of the tillage system applied. The highest soil CO{sub 2} emissions were observed for the conventional deep ploughing tillage system, and the lowest emissions were observed for the no-tillage system. The meteorological conditions greatly influenced the CO{sub 2} emissions from the soil during the spring. Soil CO{sub 2} emissions were enhanced as precipitation and the air and soil temperatures increased. Long-term investigations regarding the dynamics of CO{sub 2

  20. Performance of reproductive system of Dichelops melacanthus (Hemiptera: Pentatomidae subjected to buprofezin and pyriproxyfen: morphological analysis of ovarioles and testes

    Directory of Open Access Journals (Sweden)

    Paulo Sérgio Gimenez Cremonez

    2017-08-01

    Full Text Available The use of insecticides known as insect growth regulators, which are considered more selective to natural enemies, may be an alternative to integrated pest management of stink bugs of the main crops in Brazil. The objective of this study was to evaluate histological changes in the reproductive system of Dichelops melacanthus as well as female fecundity and egg fertility after use of growth-regulating insecticides. The insecticides used were buprofezin (a chitin biosynthesis inhibitor at a sublethal concentration (LC30 of 2.99 g L-1 and pyriproxyfen (a juvenile hormone analog at a sublethal concentration (LC30 of 8.35 mL L-1. A completely randomized experimental design was used, with 10 repetitions and 10 insects per experimental unit. Two bioassays were performed: in the first bioassay, fecundity (eggs/female and fertility (nymph eclosion of the insects that survived the insecticides were evaluated; in the second bioassay, morphological alterations of the ovarioles of adult females and of the testes of adult male insects that survived the insecticides were evaluated. Buprofezin and pyriproxyfen did not affect the adult sex ratio or female fecundity. Pyriproxyfen reduced the percentage of ecloded nymphs (71.6% compared with that of the control and buprofezin (96.4 and 90.6%, respectively treatments and had an ovicidal effect, with direct and indirect action on embryogenesis. Morphological changes were observed in both treatments with buprofezin and pyriproxyfen. The alterations observed in female and male reproductive systems may occur by the action of buprofezin and pyriproxyfen on the morphology of both ovarioles and testes.

  1. Reduction of Subjective and Objective System Complexity

    Science.gov (United States)

    Watson, Michael D.

    2015-01-01

    Occam's razor is often used in science to define the minimum criteria to establish a physical or philosophical idea or relationship. Albert Einstein is attributed the saying "everything should be made as simple as possible, but not simpler". These heuristic ideas are based on a belief that there is a minimum state or set of states for a given system or phenomena. In looking at system complexity, these heuristics point us to an idea that complexity can be reduced to a minimum. How then, do we approach a reduction in complexity? Complexity has been described as a subjective concept and an objective measure of a system. Subjective complexity is based on human cognitive comprehension of the functions and inter relationships of a system. Subjective complexity is defined by the ability to fully comprehend the system. Simplifying complexity, in a subjective sense, is thus gaining a deeper understanding of the system. As Apple's Jonathon Ive has stated," It's not just minimalism or the absence of clutter. It involves digging through the depth of complexity. To be truly simple, you have to go really deep". Simplicity is not the absence of complexity but a deeper understanding of complexity. Subjective complexity, based on this human comprehension, cannot then be discerned from the sociological concept of ignorance. The inability to comprehend a system can be either a lack of knowledge, an inability to understand the intricacies of a system, or both. Reduction in this sense is based purely on a cognitive ability to understand the system and no system then may be truly complex. From this view, education and experience seem to be the keys to reduction or eliminating complexity. Objective complexity, is the measure of the systems functions and interrelationships which exist independent of human comprehension. Jonathon Ive's statement does not say that complexity is removed, only that the complexity is understood. From this standpoint, reduction of complexity can be approached

  2. The valuation system: a coordinate-based meta-analysis of BOLD fMRI experiments examining neural correlates of subjective value.

    Science.gov (United States)

    Bartra, Oscar; McGuire, Joseph T; Kable, Joseph W

    2013-08-01

    Numerous experiments have recently sought to identify neural signals associated with the subjective value (SV) of choice alternatives. Theoretically, SV assessment is an intermediate computational step during decision making, in which alternatives are placed on a common scale to facilitate value-maximizing choice. Here we present a quantitative, coordinate-based meta-analysis of 206 published fMRI studies investigating neural correlates of SV. Our results identify two general patterns of SV-correlated brain responses. In one set of regions, both positive and negative effects of SV on BOLD are reported at above-chance rates across the literature. Areas exhibiting this pattern include anterior insula, dorsomedial prefrontal cortex, dorsal and posterior striatum, and thalamus. The mixture of positive and negative effects potentially reflects an underlying U-shaped function, indicative of signal related to arousal or salience. In a second set of areas, including ventromedial prefrontal cortex and anterior ventral striatum, positive effects predominate. Positive effects in the latter regions are seen both when a decision is confronted and when an outcome is delivered, as well as for both monetary and primary rewards. These regions appear to constitute a "valuation system," carrying a domain-general SV signal and potentially contributing to value-based decision making. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. An Industrial Analysis for Integrating Business Subjects.

    Science.gov (United States)

    Kapusinski, Albert T.

    1986-01-01

    Describes the industrial analysis seminar at Caldwell College (New Jersey), which was designed to be a capstone course for undergraduate business majors, allowing them to bring business topics into focus by using all their collected business acumen: accounting, marketing, management, economics, law, etc. (CT)

  4. Subjectivity

    Directory of Open Access Journals (Sweden)

    Jesús Vega Encabo

    2015-11-01

    Full Text Available In this paper, I claim that subjectivity is a way of being that is constituted through a set of practices in which the self is subject to the dangers of fictionalizing and plotting her life and self-image. I examine some ways of becoming subject through narratives and through theatrical performance before others. Through these practices, a real and active subjectivity is revealed, capable of self-knowledge and self-transformation. 

  5. Developing a biomedical expert finding system using medical subject headings.

    Science.gov (United States)

    Singh, Harpreet; Singh, Reema; Malhotra, Arjun; Kaur, Manjit

    2013-12-01

    Efficient identification of subject experts or expert communities is vital for the growth of any organization. Most of the available expert finding systems are based on self-nomination, which can be biased, and are unable to rank experts. Thus, the objective of this work was to develop a robust and unbiased expert finding system which can quantitatively measure expertise. Medical Subject Headings (MeSH) is a controlled vocabulary developed by the National Library of Medicine (NLM) for indexing research publications, articles and books. Using the MeSH terms associated with peer-reviewed articles published from India and indexed in PubMed, we developed a Web-based program which can be used to identify subject experts and subjects associated with an expert. We have extensively tested our system to identify experts from India in various subjects. The system provides a ranked list of experts where known experts rank at the top of the list. The system is general; since it uses information available with the PubMed, it can be implemented for any country. The expert finding system is able to successfully identify subject experts in India. Our system is unique because it allows the quantification of subject expertise, thus enabling the ranking of experts. Our system is based on peer-reviewed information. Use of MeSH terms as subjects has standardized the subject terminology. The system matches requirements of an ideal expert finding system.

  6. The User-Subjective Approach to Personal Information Management Systems.

    Science.gov (United States)

    Bergman, Ofer; Beyth-Marom, Ruth; Nachmias, Rafi

    2003-01-01

    Explains personal information management (PIM) systems and suggests a user-subjective approach to PIM system design. Advocates that PIM systems relate to the subjective value-added attributes that the user gives the stored data so that the user can find information again, recall it when needed, and use it effectively in the next interaction.…

  7. Comparative Genomic Analysis of Nontuberculous Mycobacteria (NTM) and Environmental Isolates Associated with a Simulated Chloraminated Drinking Water Distribution System Subjected to Episodes of Nitrification - poster #2168

    Science.gov (United States)

    Bacterial populations were examined in a simulated chloraminated drinking water distribution system. After six months of continuous operation, coupons were incubated in CDC reactors receiving water from the simulated system to study biofilm development. The distribution system wa...

  8. Comparative Genomic Analysis of Nontuberculous Mycobacteria (NTM) and Environmental isolates associated with a Simulated Chloraminated Drinking Water Distribution System Subjected to Episodes of Nitrification

    Science.gov (United States)

    Bacterial populations were examined in a simulated chloraminated drinking water distribution system. After six months of continuous operation, coupons were incubated in CDC reactors receiving water from the simulated system to study biofilm development. The distribution system ...

  9. Danish Passives and Subject Positions as a Mood System--A Content Analysis; and Paradigmatic Structure, Word Order and Grammaticalization. ROLIG-Papir 54.

    Science.gov (United States)

    Heltoft, Lars; Jakobsen, Lisbeth Falster

    Two papers on linguistic theory are presented. The first examines the relationship between two subsystems of Danish grammar: (1) the morphology and meaning of the two passives (a morphological passive and a periphrastic passive); and (2) the word order rules and meanings attached to indefinite subjects, irrespective of voice. It is claimed that…

  10. A biomechanical analysis of trunk and pelvis motion during gait in subjects with knee osteoarthritis compared to control subjects.

    Science.gov (United States)

    Linley, Heather S; Sled, Elizabeth A; Culham, Elsie G; Deluzio, Kevin J

    2010-12-01

    Trunk lean over the stance limb during gait has been linked to a reduction in the knee adduction moment, which is associated with joint loading. We examined differences in knee adduction moments and frontal plane trunk lean during gait between subjects with knee osteoarthritis and a control group of healthy adults. Gait analysis was performed on 80 subjects (40 osteoarthritis). To define lateral trunk lean two definitions were used. The line connecting the midpoint between two reference points on the pelvis and the midpoint between the acromion processes was projected onto the lab frontal plane and the pelvis frontal plane. Pelvic tilt was also measured in the frontal plane as the angle between the pelvic and lab coordinate systems. Angles were calculated across the stance phase of gait. We analyzed the data, (i) by extracting discrete parameters (mean and peak) waveform values, and (ii) using principal component analysis to extract shape and magnitude differences between the waveforms. Osteoarthritis subjects had a higher knee adduction moment than the control group (α=0.05). Although the discrete parameters for trunk lean did not show differences between groups, principal component analysis did detect characteristic waveform differences between the control and osteoarthritis groups. A thorough biomechanical analysis revealed small differences in the pattern of motion of the pelvis and the trunk between subjects with knee osteoarthritis and control subjects; however these differences were only detectable using principal component analysis. Copyright © 2010 Elsevier Ltd. All rights reserved.

  11. METHODICAL ENSURING ELECTRONIC SUBJECT ANALYSIS OF DOCUMENTS: FEATURES OF EDITING SUBJECT HEADINGS IN ABIS ABSOTHEQUE UNICODE

    Directory of Open Access Journals (Sweden)

    Т. М. Бикова

    2016-03-01

    Full Text Available The purpose of our article is consideration of questions of electronic subject analysis of documents and methodical ensuring editing subject headings in the electronic catalog. The main objective of our article – to show a technique of editing the dictionary of subject headings, to study and apply this technique in work of libraries of higher education institutions. Object of research is the thesaurus of subject headings of the electronic catalog of the Scientific Library of Odessa I. I. Mechnikov National University. To improve the efficiency and quality of the search capabilities of the electronic catalog needs constant work on its optimization, that is, technical editing of subject headings, the opening of new subject headings and subheadings.  In Scientific library the instruction, which regulates a technique of edition of subject headings, was developed and put into practice and establishes rationing of this process. The main finding of the work should be to improve the level of bibliographic service users and rationalization systematizer. The research findings have the practical value for employees of libraries.

  12. System and method for acquisition management of subject position information

    Science.gov (United States)

    Carrender, Curt

    2005-12-13

    A system and method for acquisition management of subject position information that utilizes radio frequency identification (RF ID) to store position information in position tags. Tag programmers receive position information from external positioning systems, such as the Global Positioning System (GPS), from manual inputs, such as keypads, or other tag programmers. The tag programmers program each position tag with the received position information. Both the tag programmers and the position tags can be portable or fixed. Implementations include portable tag programmers and fixed position tags for subject position guidance, and portable tag programmers for collection sample labeling. Other implementations include fixed tag programmers and portable position tags for subject route recordation. Position tags can contain other associated information such as destination address of an affixed subject for subject routing.

  13. System and method for acquisition management of subject position information

    Energy Technology Data Exchange (ETDEWEB)

    Carrender, Curt (Morgan Hill, CA)

    2007-01-23

    A system and method for acquisition management of subject position information that utilizes radio frequency identification (RF ID) to store position information in position tags. Tag programmers receive position information from external positioning systems, such as the Global Positioning System (GPS), from manual inputs, such as keypads, or other tag programmers. The tag programmers program each position tag with the received position information. Both the tag programmers and the position tags can be portable or fixed. Implementations include portable tag programmers and fixed position tags for subject position guidance, and portable tag programmers for collection sample labeling. Other implementations include fixed tag programmers and portable position tags for subject route recordation. Position tags can contain other associated information such as destination address of an affixed subject for subject routing.

  14. Content analysis of subjective experiences in partial epileptic seizures.

    Science.gov (United States)

    Johanson, Mirja; Valli, Katja; Revonsuo, Antti; Wedlund, Jan-Eric

    2008-01-01

    A new content analysis method for systematically describing the phenomenology of subjective experiences in connection with partial epileptic seizures is described. Forty patients provided 262 descriptions of subjective experience relative to their partial epileptic seizures. The results revealed that subjective experiences during seizures consist mostly of sensory and bodily sensations, hallucinatory experiences, and thinking. The majority of subjective experiences during seizures are bizarre and distorted; nevertheless, the patients are able to engage in adequate behavior. To the best of our knowledge, this is the first study for which detailed subjective seizure descriptions were collected immediately after each seizure and the first study in which the content of verbal reports of subjective experiences during seizures, including both the ictal and postictal experiences, has been analyzed in detail.

  15. Integrating Character Education Model With Spiral System In Chemistry Subject

    Science.gov (United States)

    Hartutik; Rusdarti; Sumaryanto; Supartono

    2017-04-01

    Integrating character education is the responsibility of all subject teachers including chemistry teacher. The integration of character education is just administrative requirements so that the character changes are not measurable. The research objective 1) describing the actual conditions giving character education, 2) mapping the character integration of chemistry syllabus with a spiral system, and 3) producing syllabus and guide system integrating character education in chemistry lessons. Of the eighteen value character, each character is mapped to the material chemistry value concepts of class X and repeated the system in class XI and class XII. Spiral system integration means integrating the character values of chemistry subjects in steps from class X to XII repeatedly at different depth levels. Besides developing the syllabus, also made the integration of characters in a learning guide. This research was designed with research and development [3] with the scope of 20 chemistry teachers in Semarang. The focus of the activities is the existence of the current character study, mapping the character values in the syllabus, and assessment of the integration guides of character education. The validity test of Syllabus and Lesson Plans by experts in FGD. The data were taken with questionnaire and interviews, then processed by descriptive analysis. The result shows 1) The factual condition, in general, the teachers designed learning one-time face-to-face with the integration of more than four characters so that behaviour changes and depth of character is poorly controlled, 2) Mapping each character values focused in the syllabus. Meaning, on one or two basic competence in four or five times, face to face, enough integrated with the value of one character. In this way, there are more noticeable changes in students behaviour. Guidance is needed to facilitate the integration of character education for teachers integrating systems. Product syllabus and guidelines

  16. Maintenance Models for Systems subject to Measurable Deterioration

    NARCIS (Netherlands)

    R.P. Nicolai (Robin)

    2008-01-01

    textabstractComplex engineering systems such as bridges, roads, flood defence structures, and power pylons play an important role in our society. Unfortunately such systems are subject to deterioration, meaning that in course of time their condition falls from higher to lower, and possibly even to

  17. Assessment of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in Down's syndrome subjects and systemically healthy subjects: A comparative clinical trial

    OpenAIRE

    Ahmed, Nizar; Parthasarathy, Harinath; Arshad, Mohamed; Victor, Dhayanand John; Mathew, Danny; Sankari, Siva

    2014-01-01

    Objectives: To compare and quantify the presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aac) and Porphyromonas gingivalis (Pg) in Down's syndrome (DS) and systemically healthy subjects with periodontitis and gingivitis. Materials and Methods: Fifty-nine age-matched subjects were categorized into four groups; Group I: DS subjects with gingivitis, Group II: DS subjects with periodontitis, Group III: Systemically healthy subjects with gingivitis and Group IV: Systemicall...

  18. Report of the Racism and Sexism in Subject Analysis Subcommittee to the RTSD/CCS Subject Analysis Committee, Midwinter 1980.

    Science.gov (United States)

    Dickinson, Elizabeth M.; And Others

    Directed toward the eradication of sexual and racial bias in bibliographic systems, the subcommittee reports its progress in the identification of areas of classification systems and subject headings requiring change. A policy statement and six guidelines establish a framework for three categories of projects: (1) the need for changes in Library…

  19. The Research on Coordinated Decision-Making Method Tax System Based on Subject Data

    Directory of Open Access Journals (Sweden)

    Zhaoji Yu

    2015-01-01

    Full Text Available Academically, the research of subject database of tax system aims to set up an efficient, harmonious virtual data application environment. Subject data, in application and management, has been on demand polymerized and autonomously collaborated and has reached a balance between instantaneity and accuracy. This paper defines the connotation and characteristics enterprise informationization, designs a value system of enterprise informationization which is subject database oriented, and builds a model for the import of the subject database of enterprise informationization. Meantime, this paper describes the structure of the subject database based information import model and forges the model’s theoretical basis of subject data import in tax system. Using the model can make an analysis on the information of data warehouse, storage information, and tax information to provide decision support for the tax administrators.

  20. Through the Camera's Eye: A Phenomenological Analysis of Teacher Subjectivity

    Science.gov (United States)

    Greenwalt, Kyle A.

    2008-01-01

    The purpose of this study is to understand how preservice teachers experience a common university assignment: the videotaping and analysis of their own instruction. Using empirical data and the thought of the French philosophers Michel Foucault and Emmanuel Levinas, the study examines the difficulties in transitioning from student subjectivity to…

  1. Status and subjects of thermal-hydraulic analysis for next-generation LWRs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The status and subjects on thermal-hydraulic analysis for next-generation light water reactors (LWRs) with passive safety systems were surveyed through about 5 years until March 1999 by subcommittee on improvement of reactor thermal-hydraulic analysis codes under the nuclear code committee in Japan Atomic Energy Research Institute. Based on the survey results and discussion, the status and subjects on system analysis for various types of proposed reactor were summarized in 1998 and those on multidimensional two-phase flow analysis were also reviewed, since the multidimensional analysis was recognized as one of the most important subjects through the investigation on system analysis. In this report, the status and subjects for the following were summarized from the survey results and discussion in 1998 and 1999; (1) BWR neutronic/thermal-hydraulic coupled analysis, (2) Evaluation of passive safety system performance and (3) Gas-liquid two-phase flow analysis. The contents in this report are the forefront of thermal-hydraulic analysis for LWRs including test results from several large-scale facilities. We expect that the contents can offer a guideline to improve reactor thermal-hydraulic analysis codes in future. (author)

  2. Simuluating quantum many-body systems subject to measurements

    DEFF Research Database (Denmark)

    Gammelmark, Søren

    We demonstrate how to simulate both discrete and continuous stochastic evolutions of a quantum many-body system subject to measurements using matrix product states. A particular, but generally applicable, measurement model is analyzed and a simple representation in terms of matrix product operators...

  3. Simulating quantum many-body systems subject to measurements

    DEFF Research Database (Denmark)

    Gammelmark, Søren

    We demonstrate how to simulate both discrete and continuous stochastic evolutions of a quantum many-body system subject to measurements using matrix product states. A particular, but generally applicable, measurement model is analyzed and a simple representation in terms of matrix product operators...

  4. Inter-individual variability of oscillatory responses to subject's own name. A single-subject analysis.

    Science.gov (United States)

    Höller, Yvonne; Kronbichler, Martin; Bergmann, Jürgen; Crone, Julia Sophia; Schmid, Elisabeth Verena; Golaszewski, Stefan; Ladurner, Gunther

    2011-06-01

    In previous studies event-related potentials and oscillations in response to subject's own name have been analyzed extensively on group-level in healthy subjects and in patients with a disorder of consciousness. Subject's own name as a deviant produces a P3. With equiprobable stimuli, non-phase-locked alpha oscillations are smaller in response to subject's own name compared to other names or subject's own name backwards. However, little is known about replicability on a single-subject level. Seventeen healthy subjects were assessed in an own-name paradigm with equiprobable stimuli of subject's own name, another name, and subject's own name backwards. Event-related potentials and non-phase locked oscillations were analyzed with single-subject, non-parametric statistics. No consistent results were found either for ERPs or for the non-phase locked changes of oscillatory activities. Only 4 subjects showed a robust effect as expected, that is, a lower activity in the alpha-beta range to subject's own name compared to other conditions. Four subjects elicited a higher activity for subject's own name. Thus, analyzing the EEG reactivity in the own-name paradigm with equiprobable stimuli on a single-subject level yields a high variance between subjects. In future research, single-subject statistics should be applied for examining the validity of physiologic measurements in other paradigms and for examining the pattern of reactivity in patients. Copyright © 2011 Elsevier B.V. All rights reserved.

  5. A Semantics-based Communication System for Dysphasic Subjects

    CERN Document Server

    Vaillant, P

    1997-01-01

    Dysphasic subjects do not have complete linguistic abilities and only produce a weakly structured, topicalized language. They are offered artificial symbolic languages to help them communicate in a way more adapted to their linguistic abilities. After a structural analysis of a corpus of utterances from children with cerebral palsy, we define a semantic lexicon for such a symbolic language. We use it as the basis of a semantic analysis process able to retrieve an interpretation of the utterances. This semantic analyser is currently used in an application designed to convert iconic languages into natural language; it might find other uses in the field of language rehabilitation.

  6. Ocular and systemic findings in a survey of aniridia subjects.

    Science.gov (United States)

    Netland, Peter A; Scott, Michele L; Boyle, John W; Lauderdale, James D

    2011-12-01

    To determine the prevalence of ocular and systemic abnormalities in a group of subjects with aniridia. Survey forms developed by Aniridia Foundation International were sent to all members prior to the 2010 AFI member conference. An additional form was provided for completion by physicians caring for patients. Forms were then collected from all members who attended the meeting. A total of 155 surveys were distributed, of which 83 (53%) were completed. The mean age was 25.4 ± 18.4 years, with 65% sporadic and 35% familial cases, and 2.4% with WAGR (Wilms' tumor, aniridia, genitourinary anomalies, and mental retardation) syndrome. Ocular abnormalities included nystagmus (83%), cataract (71%), dry eye (53%), glaucoma (46%), keratopathy (45%), foveal hypoplasia (41%), strabismus (31%), and retinal disease (5%). The mean age at diagnosis of aniridia was 22.1 months (median, 1.5 months) and glaucoma was 13.6 years (median, 8.5 years). Of 38 subjects with aniridia and glaucoma, 76% were treated medically, and 58% had been treated surgically. In subjects with glaucoma, the mean number (± SD) of glaucoma medications was 1.8 ± 1.3, and number of surgical procedures was 1.7 ± 2.0. Developmental delay was reported in 17%. The mean body mass index and the prevalence of obesity in subjects with aniridia was significantly greater (P = 0.003) than in siblings without aniridia. In this study, aniridia was associated with nystagmus and other motility problems, cataract, glaucoma, and keratopathy. Systemic abnormalities included increased average body mass index and obesity, which appeared to occur not only in WAGR syndrome but more broadly in aniridia. Copyright © 2011 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.

  7. Subjective facial analysis and its correlation with dental relationships

    Directory of Open Access Journals (Sweden)

    Gustavo Silva Siécola

    Full Text Available ABSTRACT INTRODUCTION: Subjective facial analysis is a diagnostic method that provides morphological analysis of the face. Thus, the aim of the present study was to compare the facial and dental diagnoses and investigate their relationship. METHODS: This sample consisted of 151 children (7 to 13 years old, without previous orthodontic treatment, analyzed by an orthodontist. Standardized extraoral and intraoral photographs were taken for the subjective facial classification according to Facial Pattern classification and occlusal analyses. It has been researched the occurrence of different Facial Patterns, the relationship between Facial Pattern classification in frontal and profile views, the relationship between Facial Patterns and Angle classification, and between anterior open bite and Long Face Pattern. RESULTS: Facial Pattern I was verified in 64.24% of the children, Pattern II in 21.29%, Pattern III in 6.62%, Long Face Pattern in 5.96% and Short Face Pattern in 1.99%. A substantial strength of agreement of approximately 84% between frontal and profile classification of Facial Pattern was observed (Kappa = 0.69. Agreement between the Angle classification and the Facial Pattern was seen in approximately 63% of the cases (Kappa = 0.27. Long Face Pattern did not present more open bite prevalence. CONCLUSION: Facial Patterns I and II were the most prevalent in children and the less prevalent was the Short Face Pattern. A significant concordance was observed between profile and frontal subjective facial analysis. There was slight concordance between the Facial Pattern and the sagittal dental relationships. The anterior open bite (AOB was not significantly prevalent in any Facial Pattern.

  8. Subjective facial analysis and its correlation with dental relationships

    Science.gov (United States)

    Siécola, Gustavo Silva; Capelozza, Leopoldino; Lorenzoni, Diego Coelho; Janson, Guilherme; Henriques, José Fernando Castanha

    2017-01-01

    ABSTRACT INTRODUCTION: Subjective facial analysis is a diagnostic method that provides morphological analysis of the face. Thus, the aim of the present study was to compare the facial and dental diagnoses and investigate their relationship. METHODS: This sample consisted of 151 children (7 to 13 years old), without previous orthodontic treatment, analyzed by an orthodontist. Standardized extraoral and intraoral photographs were taken for the subjective facial classification according to Facial Pattern classification and occlusal analyses. It has been researched the occurrence of different Facial Patterns, the relationship between Facial Pattern classification in frontal and profile views, the relationship between Facial Patterns and Angle classification, and between anterior open bite and Long Face Pattern. RESULTS: Facial Pattern I was verified in 64.24% of the children, Pattern II in 21.29%, Pattern III in 6.62%, Long Face Pattern in 5.96% and Short Face Pattern in 1.99%. A substantial strength of agreement of approximately 84% between frontal and profile classification of Facial Pattern was observed (Kappa = 0.69). Agreement between the Angle classification and the Facial Pattern was seen in approximately 63% of the cases (Kappa = 0.27). Long Face Pattern did not present more open bite prevalence. CONCLUSION: Facial Patterns I and II were the most prevalent in children and the less prevalent was the Short Face Pattern. A significant concordance was observed between profile and frontal subjective facial analysis. There was slight concordance between the Facial Pattern and the sagittal dental relationships. The anterior open bite (AOB) was not significantly prevalent in any Facial Pattern. PMID:28658360

  9. Analysis of sagittal condyl inclination in subjects with temporomandibular disorders

    Directory of Open Access Journals (Sweden)

    Dodić Slobodan

    2010-01-01

    Full Text Available Bacground/Aim. Disturbances of mandibular border movements is considered to be one of the major signs of temporomandibular disorders (TMD. The purpose of this study was to evaluate the possible association between disturbances of mandibular border movements and the presence of symptoms of TMD in the young. Methods. This study included two groups of volunteers between 18 and 26 years of age. The study group included 30 examineers with signs (symptoms of TMD, and the control group also included 30 persons without any signs (symptoms of TMD. The presence of TMD was confirmed according to the craniomandibular index (Helkimo. The functional analysis of mandibular movements was performed in each subject using the computer pantograph. Results. The results of this study did not confirm any significant differences between the values of the condylar variables/sagittal condylar inclination, length of the sagital condylar guidance, in the control and in the study group. Conclusion. The study did not confirm significant differences in the length and inclination of the protrusive condylar guidance, as well as in the values of the sagittal condylar inclination between the subjects with the signs and symptoms of TMD and the normal asymptomatic subjects.

  10. Perturbation Solutions for Random Linear Structural Systems subject to Random Excitation using Stochastic Differential Equations

    DEFF Research Database (Denmark)

    Köyluoglu, H.U.; Nielsen, Søren R.K.; Cakmak, A.S.

    1994-01-01

    The paper deals with the first and second order statistical moments of the response of linear systems with random parameters subject to random excitation modelled as white-noise multiplied by an envelope function with random parameters. The method of analysis is basically a second order perturbat......The paper deals with the first and second order statistical moments of the response of linear systems with random parameters subject to random excitation modelled as white-noise multiplied by an envelope function with random parameters. The method of analysis is basically a second order...... for multi-degree-of-freedom (MDOF) systems and the method is illustrated for a single-degree-of-freedom (SDOF) oscillator. The results are compared to those of exact results for a random oscillator subject to white noise excitation with random intensity....

  11. On the Optimality of Trust Network Analysis with Subjective Logic

    Directory of Open Access Journals (Sweden)

    PARK, Y.

    2014-08-01

    Full Text Available Building and measuring trust is one of crucial aspects in e-commerce, social networking and computer security. Trust networks are widely used to formalize trust relationships and to conduct formal reasoning of trust values. Diverse trust network analysis methods have been developed so far and one of the most widely used schemes is TNA-SL (Trust Network Analysis with Subjective Logic. Recent papers claimed that TNA-SL always finds the optimal solution by producing the least uncertainty. In this paper, we present some counter-examples, which imply that TNA-SL is not an optimal algorithm. Furthermore, we present a probabilistic algorithm in edge splitting to minimize uncertainty.

  12. The subjective meaning of cognitive architecture: a Marrian analysis.

    Science.gov (United States)

    Varma, Sashank

    2014-01-01

    Marr famously decomposed cognitive theories into three levels. Newell, Pylyshyn, and Anderson offered parallel decompositions of cognitive architectures, which are psychologically plausible computational formalisms for expressing computational models of cognition. These analyses focused on the objective meaning of each level - how it supports computational models that correspond to cognitive phenomena. This paper develops a complementary analysis of the subjective meaning of each level - how it helps cognitive scientists understand cognition. It then argues against calls to eliminatively reduce higher levels to lower levels, for example, in the name of parsimony. Finally, it argues that the failure to attend to the multiple meanings and levels of cognitive architecture contributes to the current, disunified state of theoretical cognitive science.

  13. Bayesian analysis of factors associated with fibromyalgia syndrome subjects

    Science.gov (United States)

    Jayawardana, Veroni; Mondal, Sumona; Russek, Leslie

    2015-01-01

    Factors contributing to movement-related fear were assessed by Russek, et al. 2014 for subjects with Fibromyalgia (FM) based on the collected data by a national internet survey of community-based individuals. The study focused on the variables, Activities-Specific Balance Confidence scale (ABC), Primary Care Post-Traumatic Stress Disorder screen (PC-PTSD), Tampa Scale of Kinesiophobia (TSK), a Joint Hypermobility Syndrome screen (JHS), Vertigo Symptom Scale (VSS-SF), Obsessive-Compulsive Personality Disorder (OCPD), Pain, work status and physical activity dependent from the "Revised Fibromyalgia Impact Questionnaire" (FIQR). The study presented in this paper revisits same data with a Bayesian analysis where appropriate priors were introduced for variables selected in the Russek's paper.

  14. Robust Filtering for Networked Stochastic Systems Subject to Sensor Nonlinearity

    Directory of Open Access Journals (Sweden)

    Guoqiang Wu

    2013-01-01

    Full Text Available The problem of network-based robust filtering for stochastic systems with sensor nonlinearity is investigated in this paper. In the network environment, the effects of the sensor saturation, output quantization, and network-induced delay are taken into simultaneous consideration, and the output measurements received in the filter side are incomplete. The random delays are modeled as a linear function of the stochastic variable described by a Bernoulli random binary distribution. The derived criteria for performance analysis of the filtering-error system and filter design are proposed which can be solved by using convex optimization method. Numerical examples show the effectiveness of the design method.

  15. Descriptive Analysis of Single Subject Research Designs: 1983-2007

    Science.gov (United States)

    Hammond, Diana; Gast, David L.

    2010-01-01

    Single subject research methodology is commonly used and cited in special education courses and journals. This article reviews the types of single subject research designs published in eight refereed journals between 1983 and 2007 used to answer applied research questions. Single subject designs were categorized as withdrawal/reversal, time…

  16. Gait analysis in demented subjects: Interests and perspectives

    Directory of Open Access Journals (Sweden)

    Olivier Beauchet

    2008-03-01

    Full Text Available Olivier Beauchet1, Gilles Allali2, Gilles Berrut3, Caroline Hommet4, Véronique Dubost5, Frédéric Assal21Department of Geriatrics, Angers University Hospital, France; 2Department of Neurology, Geneva University Hospital, France; 3Department of Geriatrics, Nantes University Hospital, France; 4Department of Internal Medicine and Geriatrics, Tours University Hospital, France; 5Department of Geriatrics, Dijon University Hospital, FranceAbstract: Gait disorders are more prevalent in dementia than in normal aging and are related to the severity of cognitive decline. Dementia-related gait changes (DRGC mainly include decrease in walking speed provoked by a decrease in stride length and an increase in support phase. More recently, dual-task related changes in gait were found in Alzheimer’s disease (AD and non-Alzheimer dementia, even at an early stage. An increase in stride-to-stride variability while usual walking and dual-tasking has been shown to be more specific and sensitive than any change in mean value in subjects with dementia. Those data show that DRGC are not only associated to motor disorders but also to problem with central processing of information and highlight that dysfunction of temporal and frontal lobe may in part explain gait impairment among demented subjects. Gait assessment, and more particularly dual-task analysis, is therefore crucial in early diagnosis of dementia and/or related syndromes in the elderly. Moreover, dual-task disturbances could be a specific marker of falling at a pre-dementia stage.Keywords: gait, prediction of dementia, risk of falling, older adult

  17. Dietary pattern analysis: a comparison between matched vegetarian and omnivorous subjects.

    Science.gov (United States)

    Clarys, Peter; Deriemaeker, Peter; Huybrechts, Inge; Hebbelinck, Marcel; Mullie, Patrick

    2013-06-13

    Dietary pattern analysis, based on the concept that foods eaten together are as important as a reductive methodology characterized by a single food or nutrient analysis, has emerged as an alternative approach to study the relation between nutrition and disease. The aim of the present study was to compare nutritional intake and the results of dietary pattern analysis in properly matched vegetarian and omnivorous subjects. Vegetarians (n = 69) were recruited via purposeful sampling and matched non-vegetarians (n = 69) with same age, gender, health and lifestyle characteristics were searched for via convenience sampling. Two dietary pattern analysis methods, the Healthy Eating Index-2010 (HEI-2010) and the Mediterranean Diet Score (MDS) were calculated and analysed in function of the nutrient intake. Mean total energy intake was comparable between vegetarians and omnivorous subjects (p > 0.05). Macronutrient analysis revealed significant differences between the mean values for vegetarians and omnivorous subjects (absolute and relative protein and total fat intake were significantly lower in vegetarians, while carbohydrate and fibre intakes were significantly higher in vegetarians than in omnivorous subjects). The HEI and MDS were significantly higher for the vegetarians (HEI = 53.8.1 ± 11.2; MDS = 4.3 ± 1.3) compared to the omnivorous subjects (HEI = 46.4 ± 15.3; MDS = 3.8 ± 1.4). Our results indicate a more nutrient dense pattern, closer to the current dietary recommendations for the vegetarians compared to the omnivorous subjects. Both indexing systems were able to discriminate between the vegetarians and the non-vegetarians with higher scores for the vegetarian subjects.

  18. Analysis of acoustic emission data for bearings subject to unbalance

    Directory of Open Access Journals (Sweden)

    Rapinder Sawhney

    2013-01-01

    Full Text Available Acoustic Emission (AE is an effective nondestructive method for investigating the behavior of materials under stress. In recent decades, AE applications in structural health monitoring have been extended to other areas such as rotating machineries and cutting tools. This research investigates the application of acoustic emission data for unbalance analysis and detection in rotary systems. The AE parameter of interest in this study is a discrete variable that covers the significance of count, duration and amplitude of AE signals. A statistical model based on Zero-Inflated Poisson (ZIP regression is proposed to handle over-dispersion and excess zeros of the counting data. The ZIP model indicates that faulty bearings can generate more transient wave in the AE waveform. Control charts can easily detect the faulty bearing using the parameters of the ZIP model. Categorical data analysis based on generalized linear models (GLM is also presented. The results demonstrate the significance of the couple unbalance.

  19. Hydroelastic analysis of a rectangular plate subjected to slamming loads

    Science.gov (United States)

    Wang, Shan; Guedes Soares, C.

    2017-12-01

    A hydroelastic analysis of a rectangular plate subjected to slamming loads is presented. An analytical model based on Wagner theory is used for calculations of transient slamming load on the ship plate. A thin isotropic plate theory is considered for determining the vibration of a rectangular plate excited by an external slamming force. The forced vibration of the plate is calculated by the modal expansion method. Analytical results of the transient response of a rectangular plate induced by slamming loads are compared with numerical calculations from finite element method. The theoretical slamming pressure based on Wagner model is applied on the finite element model of a plate. Good agreement is obtained between the analytical and numerical results for the structural deflection of a rectangular plate due to slamming pressure. The effects of plate dimension and wave profile on the structural vibration are discussed as well. The results show that a low impact velocity and a small wetted radial length of wave yield negligible effects of hydroelasticity.

  20. Hydroelastic analysis of a rectangular plate subjected to slamming loads

    Science.gov (United States)

    Wang, Shan; Guedes Soares, C.

    2017-10-01

    A hydroelastic analysis of a rectangular plate subjected to slamming loads is presented. An analytical model based on Wagner theory is used for calculations of transient slamming load on the ship plate. A thin isotropic plate theory is considered for determining the vibration of a rectangular plate excited by an external slamming force. The forced vibration of the plate is calculated by the modal expansion method. Analytical results of the transient response of a rectangular plate induced by slamming loads are compared with numerical calculations from finite element method. The theoretical slamming pressure based on Wagner model is applied on the finite element model of a plate. Good agreement is obtained between the analytical and numerical results for the structural deflection of a rectangular plate due to slamming pressure. The effects of plate dimension and wave profile on the structural vibration are discussed as well. The results show that a low impact velocity and a small wetted radial length of wave yield negligible effects of hydroelasticity.

  1. Systems engineering and analysis

    CERN Document Server

    Blanchard, Benjamin S

    2010-01-01

    For senior-level undergraduate and first and second year graduate systems engineering and related courses. A total life-cycle approach to systems and their analysis. This practical introduction to systems engineering and analysis provides the concepts, methodologies, models, and tools needed to understand and implement a total life-cycle approach to systems and their analysis. The authors focus first on the process of bringing systems into being--beginning with the identification of a need and extending that need through requirements determination, functional analysis and allocation, design synthesis, evaluation, and validation, operation and support, phase-out, and disposal. Next, the authors discuss the improvement of systems currently in being, showing that by employing the iterative process of analysis, evaluation, feedback, and modification, most systems in existence can be improved in their affordability, effectiveness, and stakeholder satisfaction.

  2. Subjective dimension in the analysis of human development

    Directory of Open Access Journals (Sweden)

    LÓPEZ NOVAL, Borja

    2012-06-01

    Full Text Available In recent years subjective evaluations about own quality of life, resumed in levels of life satisfactionor happiness, are gaining importance as indicators of development. Some authors state that subjectivewell-being is a necessary and sufficient condition for human development. In this work the arguments ofthese authors are explained and it is discussed the role subjective evaluations must play on developmentstudies. The main conclusion is that although it is necessary to integrate subjective well-being into humandevelopment studies we cannot identify subjective well-being and development.

  3. Recurrence analysis of the EEG during sleep accurately identifies subjects with mental health symptoms.

    Science.gov (United States)

    McCarty, David E; Punjabi, Naresh M; Kim, Paul Y; Frilot, Clifton; Marino, Andrew A

    2014-12-30

    Analysis of brain recurrence (ABR) is a novel computational method that uses two variables for sleep depth and two for sleep fragmentation to quantify temporal changes in non-random brain electrical activity. We postulated that ABR of the sleep-staged EEG could identify an EEG signature specific for the presence of mental health symptoms. Using the Mental Health Inventory Questionnaire (MHI-5) as ground truth, psychological distress was assessed in a study cohort obtained from the Sleep Heart Health Study. Subjects with MHI-5 50. Sixteen ABR markers derived from the EEG were analyzed using linear discriminant analysis to identify marker combinations that reliably classified individual subjects. A biomarker function computed from 12 of the markers accurately classified the subjects based on their MHI-5 scores (AUROC=82%). Use of additional markers did not improve classification accuracy. Subgroup analysis (20 highest and 20 lowest MHI-5 scores) improved classification accuracy (AUROC=89%). Biomarker values for individual subjects were significantly correlated with MHI-5 score (r=0.36, 0.54 for N=68, 40, respectively). ABR of EEGs obtained during sleep successfully classified subjects with regard to the severity of mental health symptoms, indicating that mood systems were reflected in brain electrical activity. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  4. SIMPLE: System Automatic Essay Assessment for Indonesian Language Subject Examination

    Directory of Open Access Journals (Sweden)

    Anak Agung Ratna

    2010-10-01

    Full Text Available Evaluation of study of a student is a very important aspect of an educational process. Evaluation is aimed at measuring the level of student understanding of the given lecture materials. Measuring student understanding of the course material, using essay-type exam, is generally used as the evaluation tool. In this essay-type exam, the student has to answer questions using sentences, whereby choices of possible answers are not indicated. The student has to answer the questions with his/her sentences. The answers may vary, since it reflects the student's  thoughts of the materials. One of the weaknesses of essay-type exam is the difficulty to grade the answers and it tends to be time consuming. Currently, automatic grading systems that may speed up the grading process, are being developed in many research institutions.The method used to grade, varies zorm one system to another, and one of the popular system is he Latent Semantic Analysis (LSA. LSA is a method of grading essay by extracting words and representing the sentence in the form of mathematical or statistical formulation, from a text with a relatively large number of words. The grade of the essay is determined, by matching the important words to a group of words prepared by the human rater. This paper describes an effort to developed LSA, enhanced with word weighting, word order and the word synonym to improve the accuracy of grading. This system is called SIMPLE. SIMPLE is used to grade answers using bahasa Indonesia. The exam is carried out on-line through the Web. From the experiments conducted, for small classes, the conformity of grade compared to the grade of human rater lies between 69.80 % - 94.64 %, and for medium size classes the conformity lies between 77.18 % - 98.42 % with the human rater. These results are roughly proportional with the result of LSA system, which grade essay given in English.

  5. Differences in subjective well-being within households: An analysis ...

    African Journals Online (AJOL)

    We investigate differences in subjective well-being (life satisfaction) within the household using matched data on co-resident couples drawn from the 2008 National Income Dynamics Study for South Africa. The majority of men and women in co-resident partnerships report different levels of subjective wellbeing. We use ...

  6. Analysis of embedded waste storage tanks subjected to seismic loading

    Energy Technology Data Exchange (ETDEWEB)

    Zaslawsky, M.; Sammaddar, S.; Kennedy, W.N.

    1991-12-31

    At the Savannah River Site, High Activity Wastes are stored in carbon steel tanks that are within reinforced concrete vaults. These soil-embedded tank/vault structures are approximately 80 ft. in diameter and 40 ft. deep. The tanks were studied to determine the essentials of governing variables, to reduce the problem to the least number of governing cases to optimize analysis effort without introducing excessive conservatism. The problem reduced to a limited number of cases of soil-structure interaction and fluid (tank contents) -- structure interaction problems. It was theorized that substantially reduced input would be realized from soil structure interaction (SSI) but that it was also possible that tank-to-tank proximity would result in (re)amplification of the input. To determine the governing seismic input motion, the three dimensional SSI code, SASSI, was used. Significant among the issues relative to waste tanks is to the determination of fluid response and tank behavior as a function of tank contents viscosity. Tank seismic analyses and studies have been based on low viscosity fluids (water) and the behavior is quite well understood. Typical wastes (salts, sludge), which are highly viscous, have not been the subject of studies to understand the effect of viscosity on seismic response. The computer code DYNA3D was used to study how viscosity alters tank wall pressure distribution and tank base shear and overturning moments. A parallel hand calculation was performed using standard procedures. Conclusions based on the study provide insight into the quantification of the reduction of seismic inputs for soil structure interaction for a ``soft`` soil site.

  7. Verb retrieval in brain-damaged subjects: 2. Analysis of errors.

    Science.gov (United States)

    Kemmerer, D; Tranel, D

    2000-07-01

    Verb retrieval for action naming was assessed in 53 brain-damaged subjects by administering a standardized test with 100 items. In a companion paper (Kemmerer & Tranel, 2000), it was shown that impaired and unimpaired subjects did not differ as groups in their sensitivity to a variety of stimulus, lexical, and conceptual factors relevant to the test. For this reason, the main goal of the present study was to determine whether the two groups of subjects manifested theoretically interesting differences in the kinds of errors that they made. All of the subjects' errors were classified according to an error coding system that contains 27 distinct types of errors belonging to five broad categories-verbs, phrases, nouns, adpositional words, and "other" responses. Errors involving the production of verbs that are semantically related to the target were especially prevalent for the unimpaired group, which is similar to the performance of normal control subjects. By contrast, the impaired group had a significantly smaller proportion of errors in the verb category and a significantly larger proportion of errors in each of the nonverb categories. This relationship between error rate and error type is consistent with previous research on both object and action naming errors, and it suggests that subjects with only mild damage to putative lexical systems retain an appreciation of most of the semantic, phonological, and grammatical category features of words, whereas subjects with more severe damage retain a much smaller set of features. At the level of individual subjects, a wide range of "predominant error types" were found, especially among the impaired subjects, which may reflect either different action naming strategies or perhaps different patterns of preservation and impairment of various lexical components. Overall, this study provides a novel addition to the existing literature on the analysis of naming errors made by brain-damaged subjects. Not only does the study

  8. Finite element analysis for dental implants subjected to thermal loads

    Directory of Open Access Journals (Sweden)

    Mohamad Reza Khalili

    2013-10-01

    Full Text Available   Background and Aims: Dental implants have been studied for replacement of missing teeth for many years. Productivity of implants is extremely related to the stability and resistance under applied loads and the minimum stress in jaw bone. The purpose of this study was to study numerically the 3D model of implant under thermal loads.   Materials and Methods: Bone and the ITI implant were modeled in “Solidworks” software. To obtain the exact model, the bone was assumed as a linear orthotropic material. The implant system, including implant, abutment, framework and crown were modeled and located in the bone. After importing the model in Abaqus software, the material properties and boundary conditions and loads were applied and after meshing, the model was analyzed. In this analysis, the loads were applied in two steps. In the first step, the mechanical load was applied as tightening torque to the abutment and the abutment was tightened in the implant with 35 N.cm torque. In the second step, the thermal load originated from drinking cold and hot water was applied as thermal flux on the ceramic crown surface in this model.   Results: Thermal analysis results showed that the thermal gradient in the bone was about 5.5 and 4.9 degrees of centigrade in the case of drinking cold and hot water respectively , although the maximum gradient of the whole system was reduced to 14 degrees, which occurred, in the crown by drinking cold water.   Conclusion Thermal stresses were so small and it was because of the low thermal gradient. Maximum stresses occurred in the abutment were due to the tension preloads which were originated from the tightening torque.

  9. Subjective Analysis and Objective Characterization of Adaptive Bitrate Videos

    DEFF Research Database (Denmark)

    Søgaard, Jacob; Tavakoli, Samira; Brunnström, Kjell

    2016-01-01

    The HTTP Adaptive Streaming (HAS) technology allows video service providers to improve the network utilization and thereby increasing the end-users’ Quality of Experience (QoE).This has made HAS a widely used approach for audiovisual delivery. There are several previous studies aiming to identify...... the factors influencing on subjective QoE of adaptation events.However, adapting the video quality typically lasts in a time scale much longer than what current standardized subjective testing methods are designed for, thus making the full matrix design of the experiment on an event level hard to achieve....... In this study, we investigated the overall subjective QoE of 6 minutes long video sequences containing different sequential adaptation events. This was compared to a data set from our previous work performed to evaluate the individual adaptation events. We could then derive a relationship between the overall...

  10. A Unified Analysis for Subject Topics in Brazilian Portuguese

    Directory of Open Access Journals (Sweden)

    Aroldo de Andrade

    2014-06-01

    Full Text Available In this paper we discuss the phenomenon of subject topics, consisting of the movement of either a genitive or a locative constituent into subject position in Brazilian Portuguese. This construction occurs with different verb classes, shows subject-verb agreement and precludes a resumptive pronoun. The goal of the present text is to account for its distribution. To do so, we argue that the two subclasses of unaccusative verbs found with genitive and locative topics instantiate some sort of secondary predication, and that only specific configurations allow for the movement of a constituent out of the argument structure domain. Finally, we address the comparative issue involved in explaining why the derivation of such a construction is not possible in European Portuguese.

  11. A structural analysis of an ocean going patrol boat subjected to planning loads

    Science.gov (United States)

    Clark, James H.; Lafreniere, Robert; Stoodt, Robert; Wiedenheft, John

    1987-01-01

    A static structural analysis of an ocean going patrol vessel subjected to hydrodynamic planning loads is discussed. The analysis required the development of a detailed model that included hull plating, five structural bulkheads, longitudinal and transverse stiffners, and a coarse representation of the superstructure. The finite element model was developed from fabrication drawings using the Navy computer aided design system. Various stress and displacement contours are shown for the entire hull. Because several critical areas appeared to be overstressed, these areas were remeshed for detail and are presented for completeness.

  12. Automated longitudinal intra-subject analysis (ALISA) for diffusion MRI tractography

    DEFF Research Database (Denmark)

    Aarnink, Saskia H; Vos, Sjoerd B; Leemans, Alexander

    2014-01-01

    the inter-subject and intra-subject automation in this situation are intended for subjects without gross pathology. In this work, we propose such an automated longitudinal intra-subject analysis (dubbed ALISA) approach, and assessed whether ALISA could preserve the same level of reliability as obtained...

  13. A Web Survey Analysis of Subjective Well-being

    NARCIS (Netherlands)

    Guzi, M.; de Pedraza García, P.

    2015-01-01

    Purpose - This paper explores the role of work conditions and job characteristics with respect to three subjective well-being indicators: life satisfaction, job satisfaction and satisfaction with work-life balance. From a methodological point of view, the paper shows how social sciences can benefit

  14. Performance, Pinned Down: A Lacanian Analysis of Subjectivity at Work

    NARCIS (Netherlands)

    C.M.W. Hoedemaekers (Casper)

    2008-01-01

    textabstractThis study seeks to create an account of how the performing subject comes into being within a specific organizational context. It looks at some of the ways in which managerial practices impact upon the selfhood of employees by means of the language in which they are couched. Drawing

  15. Analysis of Idiom Variation in the Framework of Linguistic Subjectivity

    Science.gov (United States)

    Liu, Zhengyuan

    2012-01-01

    Idiom variation is a ubiquitous linguistic phenomenon which has raised a lot of research questions. The past approach was either formal or functional. Both of them did not pay much attention to cognitive factors of language users. By putting idiom variation in the framework of linguistic subjectivity, we have offered a new perspective in the…

  16. Pressure transient analysis of a horizontal well subject to four ...

    African Journals Online (AJOL)

    Reservoir characterization is essential for effective reservoir and wellbore management. But when a horizontal well is subject to constant-pressure external boundaries, the extent of reservoir characterization that is possible depends on the flow regimes that are encountered in a given flow time. In this paper dimensionless ...

  17. Analysis of Subjective Conceptualizations Towards Collective Conceptual Modelling

    DEFF Research Database (Denmark)

    Glückstad, Fumiko Kano; Herlau, Tue; Schmidt, Mikkel Nørgaard

    2013-01-01

    This work is conducted as a preliminary study for a project where individuals' conceptualizations of domain knowledge will thoroughly be analyzed across 150 subjects from 6 countries. The project aims at investigating how humans' conceptualizations differ according to different types of mother la...

  18. Analysis of Subjective Conceptualizations Towards Collective Conceptual Modelling

    DEFF Research Database (Denmark)

    Kano Glückstad, Fumiko; Herlau, Tue; Schmidt, Mikkel N.

    2013-01-01

    This work is conducted as a preliminary study for a project where individuals' conceptualizations of domain knowledge will thoroughly be analyzed across 150 subjects from 6 countries. The project aims at investigating how humans' conceptualizations dier according to dierent types of mother langua...

  19. AN ANALYSIS OF SUBJECT AGREEMENT ERRORS IN ENGLISH ...

    African Journals Online (AJOL)

    Windows User

    however, continuing prevalence of a wide range of errors in students' writing. ... were written before. In English, as in many other languages, one of the grammar rules is that the subjects and the verbs must agree both in number and in person. .... The incorrect sentences which were picked were the ones which had types of.

  20. Teaching innovation system applied in business management subjects.

    Directory of Open Access Journals (Sweden)

    Rafael Rosillo

    2017-06-01

    Blunder offers a fun mobile training. We can know which student learns faster, learns more or learns better a particular topic. If a student plays the subject that the teacher has explained in class the level of learning affects to the final evaluation positively.

  1. Electroretinography in healthy subjects in relation to systemic glucocorticoid intake

    DEFF Research Database (Denmark)

    Kappelgaard, Per; Hansen, Katrine B; Vilsbøll, Tina

    2012-01-01

    This study examined electroretinographic function in healthy subjects before and after prednisolone intake. To separate the effect of prednisolone on the retina from the potentially confounding hyperglycemia-inducing effect of prednisolone, electroretinography was made while fasting and at a pre-...

  2. Systems Analysis Sub site

    Energy Technology Data Exchange (ETDEWEB)

    EERE

    2012-03-16

    Systems analysis provides direction, focus, and support for the development and introduction of hydrogen production, storage, and end-use technologies, and provides a basis for recommendations on a balanced portfolio of activities.

  3. Performatising the knower: On semiotic analysis of subject and knowledge

    Directory of Open Access Journals (Sweden)

    Artuković Kristina

    2013-01-01

    Full Text Available This paper considers epistemological implications of the concept of performative, starting from the elaborate conception provided by Judith Butler’s theories. The primary postulate of this work is that various interpretations of the performative, with their semiotic shifting from the notions of truth-evaluability and the descriptive nature of meaning, form a line of aban­doning traditional epistemological distinction between subject and object. Through other semiotic concepts which will be presented and analysed, this line reveals the key epistemological issues in the light of semiology, while Judith Butler’s concept of performativity is viewed as a possible outcome of this course of semiology of knowledge, resulting in final transcending of the category of subject.

  4. Dynamic Analysis of an Inflatable Dam Subjected to a Flood

    OpenAIRE

    Lowery, Kristen Mary

    1997-01-01

    A dynamic simulation of the response of an inflatable dam subjected to a flood was carried out to determine the survivability envelope of the dam where it can operate without rupture, or overflow. A fully nonlinear free-surface flow was applied in two dimensions using a mixed Eulerian-Lagrangian formulation. An ABAQUS finite element model was used to determine the dynamic structural response of the dam. The problem was solved in the time domain which allows the prediction of a number ...

  5. Applying queueing theory to single machine systems subject to interruptions.

    NARCIS (Netherlands)

    Wu, K.; McGinnis, L.F.; Zwart, A.P.

    2011-01-01

    Queueing models are commonly applied to quantify the performance of production systems. Prior research has usually focused on deriving queueing models for a specific type of interruptions. However, machines generally suffer multiple types of interruptions in practical manufacturing systems. To

  6. INNOVATIVE TEACHING IN ACCOUNTING SUBJECTS: ANALYSIS OF THE FLIPPED CLASSROOM

    Directory of Open Access Journals (Sweden)

    E. Lubbe

    2016-07-01

    Full Text Available Accounting students often have a negative attitude towards the subject andstruggle to understand core concepts of accounting standards. A large percentageof accounting students do not prepare for class and homework is either not doneor neglected. Many factors contributed to students struggling to prepare for classand complete homework assignments. The flipped classroom approach has grownat a rapid pace and was perceived very successful in many subjects. Little researchhas been done on the effectiveness of this approach for accounting students.Videos was created whereby accounting theory was explained and questions withexamples were given and explained. All contact sessions were transformed into anactive learning environment. During contact sessions, students were provided withquestions. Guidance was given with regards to the interpretation of a practicalcase study. Students had to analyze questions before feedback was provided tothem. Contact sessions commenced with easy questions, and progressedto moredifficult questions.Research was conducted in order to determine whether a flipped classroommethod could improve the learning experience of accounting students at a highereducation institution. The study indicated that students watched the videos beforecontact sessions, they felt more positive about their performance in accountingand improved their time management. The majority of students that completed thesurvey preferred the flipped classroom method. It enables students to learn fromtheir own mistakes in class.

  7. Equilibrium states of generic quantum systems subject to periodic driving.

    Science.gov (United States)

    Lazarides, Achilleas; Das, Arnab; Moessner, Roderich

    2014-07-01

    When a closed quantum system is driven periodically with period T, it approaches a periodic state synchronized with the drive in which any local observable measured stroboscopically approaches a steady value. For integrable systems, the resulting behavior is captured by a periodic version of a generalized Gibbs ensemble. By contrast, here we show that for generic nonintegrable interacting systems, local observables become independent of the initial state entirely. Essentially, this happens because Floquet eigenstates of the driven system at quasienergy ω(α) consist of a mixture of the exponentially many eigenstates of the undriven Hamiltonian, which are thus drawn from the entire extensive undriven spectrum. This is a form of equilibration which depends only on the Hilbert space of the undriven system and not on any details of its Hamiltonian.

  8. Model reduction of nonlinear systems subject to input disturbances

    KAUST Repository

    Ndoye, Ibrahima

    2017-07-10

    The method of convex optimization is used as a tool for model reduction of a class of nonlinear systems in the presence of disturbances. It is shown that under some conditions the nonlinear disturbed system can be approximated by a reduced order nonlinear system with similar disturbance-output properties to the original plant. The proposed model reduction strategy preserves the nonlinearity and the input disturbance nature of the model. It guarantees a sufficiently small error between the outputs of the original and the reduced-order systems, and also maintains the properties of input-to-state stability. The matrices of the reduced order system are given in terms of a set of linear matrix inequalities (LMIs). The paper concludes with a demonstration of the proposed approach on model reduction of a nonlinear electronic circuit with additive disturbances.

  9. Harmonic analysis of peripheral pulse for screening subjects at high risk of diabetes.

    Science.gov (United States)

    Jindal, G D; Jain, Rajesh Kumar; Bhat, Sushma N; Pande, Jyoti A; Sawant, Manasi S; Jindal, Sameer K; Deshpande, Alaka K

    2017-08-01

    Power spectral density (PSD) of peripheral pulses in human has been investigated in the past for its clinical applications. Continuing the efforts, data acquired using Peripheral Pulse Analyser in research projects sponsored by Board of Research in Nuclear Sciences in 207 control subjects, 18 descendants of diabetic patients and 22 patients with systemic hypertension have been subjected to PSD analysis for its study of harmonics. Application software, named Pulse Harmonic Analyser specifically developed for this work, selected 131,072 samples from each data file, obtained PSD, derived 52 PHA parameters and saved them in an Excel sheet. Coefficient of variation in control data was reduced significantly by application of Central Limit Theorem, which enabled use of parametric methods for statistical analysis of the observations. Data in hypertensive patients have shown significant difference in comparison to that of controls in eight parameters at low values of α and β. Data in offspring of diabetic patients also have shown significant difference in one parameter indicating its usefulness in screening subjects with genetic disposition of acquiring Type-II Diabetes. PHA analysis has also yielded sub-harmonic components, which are related to combined variability in the heart rate, pulse volume and pulse morphology and has a potential to become method of choice for real time variability monitoring.

  10. Analysis of Subjective Evaluation of User Experience with Headphones

    DEFF Research Database (Denmark)

    Jensen, Rasmus; Lauridsen, Nikolaj; Poulsen, Andreas

    2016-01-01

    The aspects of what provides a good user experience with headphones is initially investigated by an exploratory study (experiment I). Using KJ-Technique, 5 workshop teams of 4-6 participants each provide a number of aspects influencing their experience with headphones. Analysing the aspects...... for uniqueness and relatedness provides 144 aspects of user experience with headphones, arranged in 12 categories. The 144 influencing aspects from experiment I are condensed, and 24 attributes regarding user experience with headphones are selected. These attributes are tested in regard to their correlation...... with and effects on overall evaluation of headphones in a second experiment, thus investigating which attributes are most influential for user experience. Using a within-subject design, eight different headphones are evaluated according to the attributes along with an overall evaluation. The attributes are listed...

  11. Proteomic Analysis of Trypanosoma cruzi Epimastigotes Subjected to Heat Shock

    Directory of Open Access Journals (Sweden)

    Deyanira Pérez-Morales

    2012-01-01

    Full Text Available Trypanosoma cruzi is exposed to sudden temperature changes during its life cycle. Adaptation to these variations is crucial for parasite survival, reproduction, and transmission. Some of these conditions may change the pattern of genetic expression of proteins involved in homeostasis in the course of stress treatment. In the present study, the proteome of T. cruzi epimastigotes subjected to heat shock and epimastigotes grow normally was compared by two-dimensional gel electrophoresis followed by mass spectrometry for protein identification. Twenty-four spots differing in abundance were identified. Of the twenty-four changed spots, nineteen showed a greater intensity and five a lower intensity relative to the control. Several functional categories of the identified proteins were determined: metabolism, cell defense, hypothetical proteins, protein fate, protein synthesis, cellular transport, and cell cycle. Proteins involved in the interaction with the cellular environment were also identified, and the implications of these changes are discussed.

  12. Electroretinography in healthy subjects in relation to systemic glucocorticoid intake

    DEFF Research Database (Denmark)

    Kappelgaard, Per; Hansen, Katrine B; Vilsbøll, Tina

    2012-01-01

    to clamped hyperglycemia, neither before, nor after prednisolone (P > 0.05). The stability of ffERG performance in the face of shifting glycemia levels, which differs from what has been found in diabetes, was not influenced by the mild diabetogenic effect of the intervention on insulin resistance (P = 0......-caloric diet and by the reduction of physical activity. Full-field electroretinography (ffERG) demonstrated no significant change (P ....011) and post-prandial glycemia (P = 0.023). We conclude that prednisolone had no detectable effect on the ffERG in healthy lean men in this study. Retinal function may be less sensitive to changes in glycemia in healthy subjects than in people with diabetes, a characteristic that was unchanged by a short...

  13. Effect Size Measure and Analysis of Single Subject Designs

    Science.gov (United States)

    Society for Research on Educational Effectiveness, 2013

    2013-01-01

    One of the vexing problems in the analysis of SSD is in the assessment of the effect of intervention. Serial dependence notwithstanding, the linear model approach that has been advanced involves, in general, the fitting of regression lines (or curves) to the set of observations within each phase of the design and comparing the parameters of these…

  14. Comparative analysis of actigraphy performance in healthy young subjects

    Directory of Open Access Journals (Sweden)

    Giannina J. Bellone

    2016-10-01

    Although data accessibility and ease of use was very different for the diverse devices, there were no significant differences for sleep onset, total sleep time and sleep efficiency recordings, where applicable. In conclusion, depending on the type of study and analysis desired (as well as cost and compliance of use, we propose some relative advantages for the different actigraphy/temperature recording devices.

  15. Positive Periodic Solutions of a Periodic Discrete Competitive System Subject to Feedback Controls

    Directory of Open Access Journals (Sweden)

    Ronghua Tan

    2014-01-01

    Full Text Available Species living in a fluctuating medium and human exploitation activities might result in the duration of continuous changes. Such changes can be well-approximated as feedback controls. In this contribution a periodic discrete competitive system subject to feedback controls is proposed. By using the methods of discrete inequality, fixed point theorem, and analysis techniques, a good understanding of the existence and global asymptotic stability of positive periodic solutions is obtained. Some numerical investigations are provided to verify our analytical results.

  16. Maternal subjective well-being and preventive health care system in Japan and Finland.

    Science.gov (United States)

    Yokoyama, Yoshie; Hakulinen, Tuovi; Sugimoto, Masako; Silventoinen, Karri; Kalland, Mirjam

    2017-12-19

    Maternal well-being is an important issue not only for mothers but also for their offspring and whole families. This study aims to clarify differences in subjective well-being for mothers with infants and associated factors by comparing Japanese and Finnish mothers. In Finland, 101 mothers with infants who received health check-ups at child's age 4 months participated in the study. In Japan, 505 mothers with infants who should receive health check-ups at child's age 4 months and, whose age, age of the infant and number of children matched with the Finnish mothers were selected. The factors associated with maternal subjective well-being were explored by the linear regression analysis. All Finnish mothers had individual infant health check-ups by nurses in Child Health Clinics nearly monthly. The same nurse was responsible for following up the family throughout the years. All Japanese participants received group health check-up once at child's age 3 to 4 months, and a nurse did not cover same child and their mother. Finnish mothers showed significantly better subjective well-being compared with Japanese mothers. Whereas 85% of Finnish mothers responded that they had obtained childcare information from public health nurses, significantly fewer Japanese mothers indicated the same response (8%). Linear regression analyses disclosed that mothers' subjective well-being was associated with country, mothers' stress and age. Finnish mothers had better subjective well-being than Japanese mothers. Our results may indicate that the Finnish health care system supports mothers better than the Japanese health care system does.

  17. Finite Element Analysis of Saferooms Subjected to Tornado Impact Loads

    Science.gov (United States)

    Parfilko, Y.; Amaral de Arruda, F.; Varela, B.

    2017-10-01

    A Tornado is one of the most dreadful and unpredictable events in nature. Unfortunately, weather and geographic conditions make a large portion of the United States prone to this phenomenon. Tornado saferooms are monolithic reinforced concrete protective structures engineered to guard against these natural disasters. Saferooms must withstand impacts and wind loads from EF-5 tornadoes – where the wind speed reaches up to 150 m/s (300 mph) and airborne projectiles can reach up to 50 m/s (100 mph). The objective of this work is to evaluate the performance of a saferoom under impact from tornado-generated debris and tornado-dragged vehicles. Numerical simulations were performed to model the impact problem using explicit dynamics and energy methods. Finite element models of the saferoom, windborne debris, and vehicle models were studied using the LS-DYNA software. RHT concrete material was used to model the saferoom and vehicle models from NCAC were used to characterize damage from impacts at various speeds. Simulation results indicate good performance of the saferoom structure at vehicle impact speeds up to 25 meters per second. Damage is more significant and increases nonlinearly starting at impact velocities of 35 m/s (78 mph). Results of this study give valuable insight into the dynamic response of saferooms subjected to projectile impacts, and provide design considerations for civilian protective structures. Further work is being done to validate the models with experimental measurements.

  18. Distributed Piezoelectric Sensor System for Damage Identification in Structures Subjected to Temperature Changes.

    Science.gov (United States)

    Vitola, Jaime; Pozo, Francesc; Tibaduiza, Diego A; Anaya, Maribel

    2017-05-31

    Structural health monitoring (SHM) is a very important area in a wide spectrum of fields and engineering applications. With an SHM system, it is possible to reduce the number of non-necessary inspection tasks, the associated risk and the maintenance cost in a wide range of structures during their lifetime. One of the problems in the detection and classification of damage are the constant changes in the operational and environmental conditions. Small changes of these conditions can be considered by the SHM system as damage even though the structure is healthy. Several applications for monitoring of structures have been developed and reported in the literature, and some of them include temperature compensation techniques. In real applications, however, digital processing technologies have proven their value by: (i) offering a very interesting way to acquire information from the structures under test; (ii) applying methodologies to provide a robust analysis; and (iii) performing a damage identification with a practical useful accuracy. This work shows the implementation of an SHM system based on the use of piezoelectric (PZT) sensors for inspecting a structure subjected to temperature changes. The methodology includes the use of multivariate analysis, sensor data fusion and machine learning approaches. The methodology is tested and evaluated with aluminum and composite structures that are subjected to temperature variations. Results show that damage can be detected and classified in all of the cases in spite of the temperature changes.

  19. Maximising water supply system yield subject to multiple reliability ...

    African Journals Online (AJOL)

    The realistic incorporation of reliability into the optimisation of reservoir system design and operation remains a particularly difficult task after decades of research. While most of this research has worked with methods based on linear or dynamic programming, little has been done to find out how well the problem could be ...

  20. Design and calibration of an acoustic telemetry system subject to ...

    African Journals Online (AJOL)

    It was demonstrated that the hexagonal configuration of VR2s is optimal during isothermal conditions but inadequate during stratified conditions when acoustic dead zones of 350 m between VR2 receivers can occur. Keywords: acoustic telemetry; isothermal; system saturation; thermocline; transmitter range. African Journal ...

  1. Analysis the Competences and Contents of "Mathematics and Environmental Exploration" Subject Syllabus for Preparatory Grade

    Science.gov (United States)

    Dulama, Maria Eliza; Magda?, Ioana

    2014-01-01

    In this paper, we analyze some aspects related to "Mathematics and Environmental Exploration" subject syllabus for preparatory grade approved by Minister of National Education of Romania. The analysis aim the place of the subject syllabus into the Framework Plan; the syllabus structure and the argumentation of studying this subject; the…

  2. 47 CFR 76.905 - Standards for identification of cable systems subject to effective competition.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Standards for identification of cable systems... Regulation § 76.905 Standards for identification of cable systems subject to effective competition. (a) Only the rates of cable systems that are not subject to effective competition may be regulated. (b) A cable...

  3. URBAN EDUCATION SYSTEMS ANALYSIS.

    Science.gov (United States)

    CLARK, STEPHEN C.; AND OTHERS

    ANALYSIS OF URBAN EDUCATIONAL SYSTEMS MAY BE ACHIEVED BY USE OF AN ANALYTICAL MODEL. THE MODEL MAY BE USED IN DECISION-MAKING REGARDING SCHOOL LOCATION, ENROLLMENT, FACILITIES, ORGANIZATION, PROGRAMS AND COSTS. KNOWN DATA SUCH AS MONIES AVAILABLE, STAFF ALLOCATION, AND CURRENT SCHOOL PLANT ARE INTRODUCED INTO THE MODEL. IN THE STRUCTURE OF THE…

  4. Analysis of the cephalometric pattern of Brazilian achondroplastic adult subjects

    Directory of Open Access Journals (Sweden)

    Renato Cardoso

    2012-12-01

    Full Text Available OBJECTIVE: The aim of this study was to assess the position of the cranial base, maxilla, and mandible of Brazilian achondroplastic adult subjects through cephalometric measurements of the cranio-dento-facial complex, and to compare the results to normal patterns established in literature. METHODS: Fourteen achondroplastic adult subjects were evaluated based on their radiographic cephalometric measurements, which were obtained using the tracings proposed by Downs, Steinner, Bjork, Ricketts and McNamara. Statistical comparison of the means was performed with Student's t test. RESULTS: When compared to normal patterns, the cranial base presented a smaller size in both its anterior and posterior portions, the cranial base angle was acute and there was an anterior projection of the porion; the maxilla was found to be smaller in size in both the anteroposterior and transversal directions, it was inclined anteriorly with anterior vertical excess, and retropositioned in relation to the cranial base and to the mandible; the mandible presented a normal-sized ramus, a decreased body and transverse dimension, a tendency towards vertical growth and clockwise rotation, and it was slightly protruded in relation to the cranial base and maxilla. CONCLUSION: Although we observed wide individual variation in some parameters, it was possible to identify significant differences responsible for the phenotypical characteristics of achondroplastic patients.OBJETIVO: avaliar o tamanho e o posicionamento da base do crânio, da maxila e da mandíbula de indivíduos acondroplásicos brasileiros adultos, a partir de medidas cefalométricas do complexo dentoesqueletofacial. Confrontar os dados obtidos aos padrões de normalidade estabelecidos na literatura. MÉTODOS: foram avaliados 14 indivíduos acondroplásicos adultos, utilizando algumas grandezas cefalométricas radiográficas obtidas a partir dos traçados preconizados por Downs, Steinner, Björk, Ricketts e Mc

  5. Nonlinear Analysis of Frame Structures Subjected to Blast Overpressures

    Science.gov (United States)

    1977-05-01

    inv thaersecondarysframinge ofeua shockn font praessur asd therbatost wav traersesontheystructure plan of the roof and walls from one framing bay to... treatment of f’mese second order effects would sig- nificantly increase the compiexity of the frame analysis. How- ever, both of these effects can be...elastic restraint at (B): A- Aa) + (l/2)(AyB - Am) ABB =0 Case 5 - Yield at (A); pin at (B): ABA AyA- A / A6B = 0 Case 6- Elastic restraint at (A); yield at

  6. Neptune Aerocapture Systems Analysis

    Science.gov (United States)

    Lockwood, Mary Kae

    2004-01-01

    A Neptune Aerocapture Systems Analysis is completed to determine the feasibility, benefit and risk of an aeroshell aerocapture system for Neptune and to identify technology gaps and technology performance goals. The high fidelity systems analysis is completed by a five center NASA team and includes the following disciplines and analyses: science; mission design; aeroshell configuration screening and definition; interplanetary navigation analyses; atmosphere modeling; computational fluid dynamics for aerodynamic performance and database definition; initial stability analyses; guidance development; atmospheric flight simulation; computational fluid dynamics and radiation analyses for aeroheating environment definition; thermal protection system design, concepts and sizing; mass properties; structures; spacecraft design and packaging; and mass sensitivities. Results show that aerocapture can deliver 1.4 times more mass to Neptune orbit than an all-propulsive system for the same launch vehicle. In addition aerocapture results in a 3-4 year reduction in trip time compared to all-propulsive systems. Aerocapture is feasible and performance is adequate for the Neptune aerocapture mission. Monte Carlo simulation results show 100% successful capture for all cases including conservative assumptions on atmosphere and navigation. Enabling technologies for this mission include TPS manufacturing; and aerothermodynamic methods and validation for determining coupled 3-D convection, radiation and ablation aeroheating rates and loads, and the effects on surface recession.

  7. Seismic Response of Power Transmission Tower-Line System Subjected to Spatially Varying Ground Motions

    Directory of Open Access Journals (Sweden)

    Li Tian

    2010-01-01

    Full Text Available The behavior of power transmission tower-line system subjected to spatially varying base excitations is studied in this paper. The transmission towers are modeled by beam elements while the transmission lines are modeled by cable elements that account for the nonlinear geometry of the cables. The real multistation data from SMART-1 are used to analyze the system response subjected to spatially varying ground motions. The seismic input waves for vertical and horizontal ground motions are also generated based on the Code for Design of Seismic of Electrical Installations. Both the incoherency of seismic waves and wave travel effects are accounted for. The nonlinear time history analytical method is used in the analysis. The effects of boundary conditions, ground motion spatial variations, the incident angle of the seismic wave, coherency loss, and wave travel on the system are investigated. The results show that the uniform ground motion at all supports of system does not provide the most critical case for the response calculations.

  8. DOMAIN-DRIVEN DESIGN APPLICATION AND IMPLEMENTATION OF INFORMATION SYSTEMS FOR CLIENTS QUEUING SUBJECT AREAS

    Directory of Open Access Journals (Sweden)

    P. P. Oleynik

    2015-11-01

    Full Text Available The paper deals with domain-driven design applicability of information systems for client queuing subject areas. The following optimality criteria were put forward for the final implementation: the possibility of automation with a single system both for small institution and a whole network of institutions; advanced graphical interface with support for sensor screens; implementation of multi-users account of orders from clients; flexible application architecture with the ability of future enhancement; ability of integration with a variety of peripherals. The necessity of each criterion definition is shown. For implementability estimation, test information system was designed, automating the queuing system. Unified modeling language UML is used. Description of each class functionality is given and the association with other classes as well. Attention is paid to the design of tree (hierarchical structures and selection procedure of base classes based on the analysis of existing common attributes. For the system implementation, its own development environment SharpArchitect RAD Studio is used, offering MDA approach for implementation of systems based on standardized meta object system. A graphical view of order form developed prototype is presented, composition and structure are described, and notation developed by the author is given simplifying the prototyping process. Approaches to differentiation of access rights for different user roles are shown. Conformity of the received implementation to each selected optimality criterion is determined. Recommendations for further system development are given.

  9. Vibration Effects of Nonclassically Damped Building-Piping Systems Subjected to Extreme Loads

    Directory of Open Access Journals (Sweden)

    YongHee Ryu

    2016-01-01

    Full Text Available Piping leakage can occur at T-joint, elbows, valves, or nozzles in nuclear power plants and nonnuclear power plants such as petrochemical plants when subjected to extreme loads and such leakage of piping systems can also lead to fire or explosion. For example, leakage of sodium, toxic gases, or nitrogen in hospitals can cause man-made hazards. The primary objective of this research is to understand the vibration effects due to classical/nonclassical damping with building-piping systems under extreme loads. The current evaluation employed finite-element analysis to calculate the effects of the responses of classically and nonclassically damped building-piping systems. Classical and nonclassical damping matrices for a coupled primary-secondary system were developed based on the Rayleigh equation. A total of 10 selected ground motions were applied to single degree of freedom (SDOF primary-SDOF secondary (2-DOF coupled systems in which the ratios of the natural frequencies between the primary and secondary systems ranged between 0.9 and 1.1. It revealed that the vibration effect of nonclassical damping was significant where the natural frequencies of the two systems were nearly tuned. For piping-material nonlinearity, the effects of nonclassical damping on the result forces of piping systems were not significantly different from those of classical damping.

  10. Analysis of Subjective Evaluation of User Experience with Headphones

    DEFF Research Database (Denmark)

    Jensen, Rasmus; Lauridsen, Nikolaj; Poulsen, Andreas

    2016-01-01

    in the following categories: sound quality, comfort, build quality, design and brand. A factor analysis shows that the categories fit the attributes. Furthermore, some attributes show high correlations with the overall evaluation, suggesting that these attributes are important for user experience with headphones......The aspects of what provides a good user experience with headphones is initially investigated by an exploratory study (experiment I). Using KJ-Technique, 5 workshop teams of 4-6 participants each provide a number of aspects influencing their experience with headphones. Analysing the aspects...... for uniqueness and relatedness provides 144 aspects of user experience with headphones, arranged in 12 categories. The 144 influencing aspects from experiment I are condensed, and 24 attributes regarding user experience with headphones are selected. These attributes are tested in regard to their correlation...

  11. Subjective experience analysis in women with breast cancer

    Directory of Open Access Journals (Sweden)

    Miriam Belber-Gómez

    2018-01-01

    Full Text Available In this article the psychological experience and needs shown in the discourse of women diagnosed with breast cancer in a psychological group intervention was analyzed. The sessions are transcribed and a discourse analysis is performed, selecting the most prevailing topics. The main psychological difficulties perceived by the participants are the following: body identity change, sexuality changes, new quality of interpersonal relationships, implications of positive thinking culture, fear of recurrence, the relationship with the hospital staff and change after diagnosis. The aspects of the group considered to be helpful are also addressed, i.e. feeling understood by the others, seeing the rest of participants as coping models, changing their relationship with the illness. Several clinical implications are highlighted in order to improve a comprehensive care.

  12. Psalm 151 of the Septuagint: a Subject Analysis

    Directory of Open Access Journals (Sweden)

    Veviurko Il'ia

    2016-01-01

    Full Text Available By its location in the Septuagint canon, Psalm 151 takes up a place of a certain epilogue of the whole Psalter. Due to its isolation in the Greek text and non-canonicity from the masoretic point of view, as well as to its apparent simplicity and triviality, the Psalm was not often attracting attention of the biblical scholars. Only after discovering of a longer Hebrew version of the Psalm in Qumran the situation began to change. Now the Greek Ps 151 has being engaged into comparative study, but generally remaining in the shadow of the Qumran text. This article deals principally with Septuagint version of the Psalm, that underlies the Slavonic and others recensions adopted in the Christian tradition. A through thematical analysis, beginning with the presumption of the texts meaningfulness, will allow then to compare it with the longer Qumran version, the latter to be found poetical interpretation of the former. The analysis reveals David of the Ps 151 to be very much archetypical than historical personality. This is enough to explain the almost complete withdrawal of the emotional «colours», though not depriving the Psalm of its poetical expressiveness. The hero of Ps 151 is a silhouette with some trates of the Anoited One that cometh. This conclusion leads us to the proper estimation of the significance of the Psalm in the history of religious ideas: by the examination of this text we can determine more exactly, what kind of characteristics of the Psalters David collected in its ‘epilogue’ were perceived by the readers as protomessianic: the stainless moral purity, the unfamiliarity to the world, the mysterious conversation with God, the natural possession of power as a mode of the direct divine activity, and the readiness to became a ransomer for the people.

  13. Network systems security analysis

    Science.gov (United States)

    Yilmaz, Ä.°smail

    2015-05-01

    Network Systems Security Analysis has utmost importance in today's world. Many companies, like banks which give priority to data management, test their own data security systems with "Penetration Tests" by time to time. In this context, companies must also test their own network/server systems and take precautions, as the data security draws attention. Based on this idea, the study cyber-attacks are researched throughoutly and Penetration Test technics are examined. With these information on, classification is made for the cyber-attacks and later network systems' security is tested systematically. After the testing period, all data is reported and filed for future reference. Consequently, it is found out that human beings are the weakest circle of the chain and simple mistakes may unintentionally cause huge problems. Thus, it is clear that some precautions must be taken to avoid such threats like updating the security software.

  14. A System Analysis Tool

    Energy Technology Data Exchange (ETDEWEB)

    CAMPBELL,PHILIP L.; ESPINOZA,JUAN

    2000-06-01

    In this paper we describe a tool for analyzing systems. The analysis is based on program slicing. It answers the following question for the software: if the value of a particular variable changes, what other variable values also change, and what is the path in between? program slicing was developed based on intra-procedure control and data flow. It has been expanded commercially to inter-procedure flow. However, we extend slicing to collections of programs and non-program entities, which we term multi-domain systems. The value of our tool is that an analyst can model the entirety of a system, not just the software, and we believe that this makes for a significant increase in power. We are building a prototype system.

  15. Automated document analysis system

    Science.gov (United States)

    Black, Jeffrey D.; Dietzel, Robert; Hartnett, David

    2002-08-01

    A software application has been developed to aid law enforcement and government intelligence gathering organizations in the translation and analysis of foreign language documents with potential intelligence content. The Automated Document Analysis System (ADAS) provides the capability to search (data or text mine) documents in English and the most commonly encountered foreign languages, including Arabic. Hardcopy documents are scanned by a high-speed scanner and are optical character recognized (OCR). Documents obtained in an electronic format bypass the OCR and are copied directly to a working directory. For translation and analysis, the script and the language of the documents are first determined. If the document is not in English, the document is machine translated to English. The documents are searched for keywords and key features in either the native language or translated English. The user can quickly review the document to determine if it has any intelligence content and whether detailed, verbatim human translation is required. The documents and document content are cataloged for potential future analysis. The system allows non-linguists to evaluate foreign language documents and allows for the quick analysis of a large quantity of documents. All document processing can be performed manually or automatically on a single document or a batch of documents.

  16. EMOTIONAL AND VOLITIONAL RELIABILITY AS A SUBJECT OF SCIENTIFIC ANALYSIS

    Directory of Open Access Journals (Sweden)

    Xia Juan

    2016-11-01

    Full Text Available The article analyses the scientists’ views on the phenomenon of “reliability”. The author pays special attention to the fact that the concept “reliability” is considered by the scientists as the systematic characteristic, which is characterized by the specific number of professional, psychological, physiological qualities and functions at the different levels of a person’s activity. This activity provides stable and reliable work. It is found out that scientists think the quality is the most important property which provides definiteness to any phenomenon. Personal qualities that affect the maturity of emotional and volitional reliability are established. Scientific interpretation of the concept of “reliability” and the main features of performing reliability is revealed. The analysis of pedagogical and psychological literature proves that the emotional qualities are being formed throughout the life according to the person’s environmental and genetic conditions. Emotional irritability, emotional stability, emotional tone, emotional reactions, emotional stability are the qualities which depend upon a type of a person’s higher nervous activity. The person’s activity, especially music one, can’t exist without involving emotions and feelings. Music plays an important role; due to it emotions become conscious processes. Thanks to music the person’s higher emotions (moral, intellectual, esthetic are formed. It is noticed that individual differences in demonstration of emotions depend on a person’s volitional qualities. Volition is considered to be a person’s psychological activity that determines purposefulness of actions. The author concluded that the maturity level of emotional and volitional reliability depends on direction and resistance of socially significant motives (needs, interests, values, attitudes; personality’s psychophysical traits (abilities, capacities, which provide the required level and effectiveness

  17. A general symplectic method for the response analysis of infinitely periodic structures subjected to random excitations

    Directory of Open Access Journals (Sweden)

    You-Wei Zhang

    Full Text Available A general symplectic method for the random response analysis of infinitely periodic structures subjected to stationary/non-stationary random excitations is developed using symplectic mathematics in conjunction with variable separation and the pseudo-excitation method (PEM. Starting from the equation of motion for a single loaded substructure, symplectic analysis is firstly used to eliminate the dependent degrees of the freedom through condensation. A Fourier expansion of the condensed equation of motion is then applied to separate the variables of time and wave number, thus enabling the necessary recurrence scheme to be developed. The random response is finally determined by implementing PEM. The proposed method is justified by comparison with results available in the literature and is then applied to a more complicated time-dependent coupled system.

  18. Online Search + Logic Programming = Subject Bibliography: An Expert Systems Approach to Bibliographic Processing.

    Science.gov (United States)

    Lirov, Yuval; Lirov, Viktor

    1990-01-01

    Describes the development of a knowledge-based system, REX, that creates subject bibliographies by downloading reference material from an online bibliographic service. The expert systems architecture is explained, use of Prolog is described, and creation of the subject knowledge base and an author index are discussed. (10 references) (LRW)

  19. Running interfacial waves in a two-layer fluid system subject to longitudinal vibrations.

    Science.gov (United States)

    Goldobin, D S; Pimenova, A V; Kovalevskaya, K V; Lyubimov, D V; Lyubimova, T P

    2015-05-01

    We study the waves at the interface between two thin horizontal layers of immiscible fluids subject to high-frequency horizontal vibrations. Previously, the variational principle for energy functional, which can be adopted for treatment of quasistationary states of free interface in fluid dynamical systems subject to vibrations, revealed the existence of standing periodic waves and solitons in this system. However, this approach does not provide regular means for dealing with evolutionary problems: neither stability problems nor ones associated with propagating waves. In this work, we rigorously derive the evolution equations for long waves in the system, which turn out to be identical to the plus (or good) Boussinesq equation. With these equations one can find all the time-independent-profile solitary waves (standing solitons are a specific case of these propagating waves), which exist below the linear instability threshold; the standing and slow solitons are always unstable while fast solitons are stable. Depending on initial perturbations, unstable solitons either grow in an explosive manner, which means layer rupture in a finite time, or falls apart into stable solitons. The results are derived within the long-wave approximation as the linear stability analysis for the flat-interface state [D.V. Lyubimov and A.A. Cherepanov, Fluid Dynamics 21, 849 (1986)] reveals the instabilities of thin layers to be long wavelength.

  20. An intelligent recovery progress evaluation system for ACL reconstructed subjects using integrated 3-D kinematics and EMG features.

    Science.gov (United States)

    Malik, Owais A; Senanayake, S M N Arosha; Zaheer, Dansih

    2015-03-01

    An intelligent recovery evaluation system is presented for objective assessment and performance monitoring of anterior cruciate ligament reconstructed (ACL-R) subjects. The system acquires 3-D kinematics of tibiofemoral joint and electromyography (EMG) data from surrounding muscles during various ambulatory and balance testing activities through wireless body-mounted inertial and EMG sensors, respectively. An integrated feature set is generated based on different features extracted from data collected for each activity. The fuzzy clustering and adaptive neuro-fuzzy inference techniques are applied to these integrated feature sets in order to provide different recovery progress assessment indicators (e.g., current stage of recovery, percentage of recovery progress as compared to healthy group, etc.) for ACL-R subjects. The system was trained and tested on data collected from a group of healthy and ACL-R subjects. For recovery stage identification, the average testing accuracy of the system was found above 95% (95-99%) for ambulatory activities and above 80% (80-84%) for balance testing activities. The overall recovery evaluation performed by the proposed system was found consistent with the assessment made by the physiotherapists using standard subjective/objective scores. The validated system can potentially be used as a decision supporting tool by physiatrists, physiotherapists, and clinicians for quantitative rehabilitation analysis of ACL-R subjects in conjunction with the existing recovery monitoring systems.

  1. Risk analysis of computer system designs

    Science.gov (United States)

    Vallone, A.

    1981-01-01

    Adverse events during implementation can affect final capabilities, schedule and cost of a computer system even though the system was accurately designed and evaluated. Risk analysis enables the manager to forecast the impact of those events and to timely ask for design revisions or contingency plans before making any decision. This paper presents a structured procedure for an effective risk analysis. The procedure identifies the required activities, separates subjective assessments from objective evaluations, and defines a risk measure to determine the analysis results. The procedure is consistent with the system design evaluation and enables a meaningful comparison among alternative designs.

  2. Hanford Environmental Information System (HEIS). Volume 3, Subject Area reference manual

    Energy Technology Data Exchange (ETDEWEB)

    Schreck, R.I.

    1994-01-14

    The Hanford Environmental Information System (HEIS) Subject Area manuals are designed as reference guides, that is, each chapter provides the information needed to make best use of each subject area, its tables, and reporting capabilities. Each subject area is documented in a chapter in one of the subject area manuals. Because these are reference manuals, most of the information is also available in the online help system as well. See Section 5.4.2 of the HEIS User`s Guide (DOE-RL 1994a) for a detailed description of the online help.

  3. The effects of the Mulligan Sustained Natural Apophyseal Glide (SNAG mobilisation in the lumbar flexion range of asymptomatic subjects as measured by the Zebris CMS20 3-D motion analysis system

    Directory of Open Access Journals (Sweden)

    Strimpakos Nikolaos

    2008-10-01

    Full Text Available Abstract Background Mulligan's mobilisation techniques are thought to increase the range of movement (ROM in patients with low back pain. The primary aim of this study was to investigate the application of the Mulligan's Sustained Natural Apophyseal Glide (SNAG technique on lumbar flexion ROM. The secondary aim was to measure the intra- and inter-day reliability of lumbar ROM employing the same procedure. Methods 49 asymptomatic volunteers participated in this double-blinded study. Subjects were randomly assigned to receive either SNAG mobilisation (n = 25, or a sham mobilisation (n = 24. The SNAG technique was applied at the L3and L4 spinal levels with active flexion in sitting by an experienced manual therapist. Three sets of 10 repetitions at each of the two spinal levels were performed. The sham mobilisation was similar to the SNAG but did not apply the appropriate direction or force. Lumbar ROM was measured by a three dimensional electronic goniometer (Zebris CMS20, before and after each technique. For the reliability, five measurements in two different days (one week apart were performed in 20 healthy subjects. Results When both interventions were compared, independent t tests yielded no statistically significant results in ROM between groups (p = 0.673. Furthermore no significant within group differences were observed: SNAG (p = 0.842, sham (p = 0.169. Intra- and inter-day reliability of flexion measurements was high (ICC1,1 > 0.82, SEM Conclusion While the Zebris proved to be a reliable device for measuring lumbar flexion ROM, SNAG mobilisation did not demonstrate significant differences in flexion ROM when compared to sham mobilisation. Trial registration Current Controlled Trials NCT00678093.

  4. A Wearable System for Gait Training in Subjects with Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Filippo Casamassima

    2014-03-01

    Full Text Available In this paper, a system for gait training and rehabilitation for Parkinson’s disease (PD patients in a daily life setting is presented. It is based on a wearable architecture aimed at the provision of real-time auditory feedback. Recent studies have, in fact, shown that PD patients can receive benefit from a motor therapy based on auditory cueing and feedback, as happens in traditional rehabilitation contexts with verbal instructions given by clinical operators. To this extent, a system based on a wireless body sensor network and a smartphone has been developed. The system enables real-time extraction of gait spatio-temporal features and their comparison with a patient’s reference walking parameters captured in the lab under clinical operator supervision. Feedback is returned to the user in form of vocal messages, encouraging the user to keep her/his walking behavior or to correct it. This paper describes the overall concept, the proposed usage scenario and the parameters estimated for the gait analysis. It also presents, in detail, the hardware-software architecture of the system and the evaluation of system reliability by testing it on a few subjects.

  5. Performance Evaluation on Transmission Tower-Line System with Passive Friction Dampers Subjected to Wind Excitations

    Directory of Open Access Journals (Sweden)

    Bo Chen

    2015-01-01

    Full Text Available The vibration control and performance evaluation on a transmission-tower line system by using friction dampers subjected to wind excitations are carried out in this study. The three-dimensional finite element (FE model of a transmission tower is firstly constructed. A two-dimensional lumped mass model of a transmission tower is developed for dynamic analysis. The analytical model of transmission tower-line system is proposed by taking the dynamic interaction between the tower and the transmission lines into consideration. The mechanical model of passive friction damper is presented by involving the effects of damper axial stiffness. The equation of motion of the transmission tower-line system incorporated with the friction dampers disturbed by wind excitations is established. A real transmission tower-line system is taken as an example to examine the feasibility and reliability of the proposed control approach. An extensive parameter study is carried out to find the optimal parameters of friction damper and to assess the effects of slipping force axial stiffness and hysteresis loop on control performance. The work on an example structure indicates that the application of friction dampers with optimal parameters could significantly reduce wind-induced responses of the transmission tower-line system.

  6. Subject analysis during the cataloging process: the case of academic libraries

    Directory of Open Access Journals (Sweden)

    Jelka Kos

    2011-01-01

    Full Text Available Purpose: The study tried to answer how catalogers determine the subject of a document.The aim of the research is to understand: (1 which parts of document are most important in the subject analysis process, (2 which approaches in the subject determination are involved, (3 which features of document are most significant, (4 which stages and cognitive processes are present, and, (5 if and how the subject analysis process of catalogers at Slovenian academic libraries differ from conceptions described in textbooks and ISO 5963 standard.Methodology/approach: Ten catalogers from nine Slovenian academic libraries were included into the qualitative research. Observation, think-aloud procedures, diaries and follow up discussions (non-structured interviews were used for collecting the data.Results: Regarding the parts of the document, the participants mostly examine the title,the table of contents, the introduction/preface, they also check the entire document.The document-oriented approach to subject determination was predominant. There were four stages in the process noted: the data input, data processing, text reduction and assignment of subject headings. Based on the results two general models of the subject analysis process were constructed.Research limitation: The small and convenient sample limits the generalization of findings.Originality/practical implications: It is a rare empirical study with qualitative approach in researching the subject analysis in Slovenia.

  7. All Night Spectral Analysis of EEG Sleep in Young Adult and Middle-Aged Male Subjects

    NARCIS (Netherlands)

    Dijk, Derk Jan; Beersma, Domien G.M.; Hoofdakker, Rutger H. van den

    1989-01-01

    The sleep EEGs of 9 young adult males (age 20-28 years) and 8 middle-aged males (42-56 years) were analyzed by visual scoring and spectral analysis. In the middle-aged subjects power density in the delta, theta and sigma frequencies were attenuated as compared to the young subjects. In both age

  8. Systems, Subjects, Sessions: To What Extent Do These Factors Influence EEG Data?

    Science.gov (United States)

    Melnik, Andrew; Legkov, Petr; Izdebski, Krzysztof; Kärcher, Silke M.; Hairston, W. David; Ferris, Daniel P.; König, Peter

    2017-01-01

    Lab-based electroencephalography (EEG) techniques have matured over decades of research and can produce high-quality scientific data. It is often assumed that the specific choice of EEG system has limited impact on the data and does not add variance to the results. However, many low cost and mobile EEG systems are now available, and there is some doubt as to the how EEG data vary across these newer systems. We sought to determine how variance across systems compares to variance across subjects or repeated sessions. We tested four EEG systems: two standard research-grade systems, one system designed for mobile use with dry electrodes, and an affordable mobile system with a lower channel count. We recorded four subjects three times with each of the four EEG systems. This setup allowed us to assess the influence of all three factors on the variance of data. Subjects performed a battery of six short standard EEG paradigms based on event-related potentials (ERPs) and steady-state visually evoked potential (SSVEP). Results demonstrated that subjects account for 32% of the variance, systems for 9% of the variance, and repeated sessions for each subject-system combination for 1% of the variance. In most lab-based EEG research, the number of subjects per study typically ranges from 10 to 20, and error of uncertainty in estimates of the mean (like ERP) will improve by the square root of the number of subjects. As a result, the variance due to EEG system (9%) is of the same order of magnitude as variance due to subjects (32%/sqrt(16) = 8%) with a pool of 16 subjects. The two standard research-grade EEG systems had no significantly different means from each other across all paradigms. However, the two other EEG systems demonstrated different mean values from one or both of the two standard research-grade EEG systems in at least half of the paradigms. In addition to providing specific estimates of the variability across EEG systems, subjects, and repeated sessions, we also

  9. Systems, Subjects, Sessions: To What Extent Do These Factors Influence EEG Data?

    Science.gov (United States)

    Melnik, Andrew; Legkov, Petr; Izdebski, Krzysztof; Kärcher, Silke M; Hairston, W David; Ferris, Daniel P; König, Peter

    2017-01-01

    Lab-based electroencephalography (EEG) techniques have matured over decades of research and can produce high-quality scientific data. It is often assumed that the specific choice of EEG system has limited impact on the data and does not add variance to the results. However, many low cost and mobile EEG systems are now available, and there is some doubt as to the how EEG data vary across these newer systems. We sought to determine how variance across systems compares to variance across subjects or repeated sessions. We tested four EEG systems: two standard research-grade systems, one system designed for mobile use with dry electrodes, and an affordable mobile system with a lower channel count. We recorded four subjects three times with each of the four EEG systems. This setup allowed us to assess the influence of all three factors on the variance of data. Subjects performed a battery of six short standard EEG paradigms based on event-related potentials (ERPs) and steady-state visually evoked potential (SSVEP). Results demonstrated that subjects account for 32% of the variance, systems for 9% of the variance, and repeated sessions for each subject-system combination for 1% of the variance. In most lab-based EEG research, the number of subjects per study typically ranges from 10 to 20, and error of uncertainty in estimates of the mean (like ERP) will improve by the square root of the number of subjects. As a result, the variance due to EEG system (9%) is of the same order of magnitude as variance due to subjects (32%/sqrt(16) = 8%) with a pool of 16 subjects. The two standard research-grade EEG systems had no significantly different means from each other across all paradigms. However, the two other EEG systems demonstrated different mean values from one or both of the two standard research-grade EEG systems in at least half of the paradigms. In addition to providing specific estimates of the variability across EEG systems, subjects, and repeated sessions, we also

  10. Are Young People Subjects of Rights or…without rights? Changes in the Contravention System (Cordoba, Argentina

    Directory of Open Access Journals (Sweden)

    Mariana Jesica Lerchundi

    2017-01-01

    Full Text Available This text wants to compare the main differences between the Faults Code and Coexistence Code of the Province of Córdoba (Argentina taking young people as empirical subjects of reflection, which are the most affected by the regulations. From the content analysis and critical discourse analysis, the differences between the two standards were found. Here are detailed only some of them that allow us to infer changes in the penal system maintaining the violation of rights of young people.

  11. Analysis of stresses on buried pipeline subjected to landslide based on numerical simulation and regression analysis

    Energy Technology Data Exchange (ETDEWEB)

    Han, Bing; Jing, Hongyuan; Liu, Jianping; Wu, Zhangzhong [PetroChina Pipeline RandD Center, Langfang, Hebei (China); Hao, Jianbin [School of Petroleum Engineering, Southwest Petroleum University, Chengdu, Sichuan (China)

    2010-07-01

    Landslides have a serious impact on the integrity of oil and gas pipelines in the tough terrain of Western China. This paper introduces a solving method of axial stress, which uses numerical simulation and regression analysis for the pipelines subjected to landslides. Numerical simulation is performed to analyze the change regularity of pipe stresses for the five vulnerability assessment indexes, which are: the distance between pipeline and landslide tail; the thickness of landslide; the inclination angle of landslide; the pipeline length passing through landslide; and the buried depth of pipeline. A pipeline passing through a certain landslide in southwest China was selected as an example to verify the feasibility and effectiveness of this method. This method has practical applicability, but it would need large numbers of examples to better verify its reliability and should be modified accordingly. Also, it only considers the case where the direction of the pipeline is perpendicular to the primary slip direction of the landslide.

  12. System of systems modeling and analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, James E.; Anderson, Dennis James; Longsine, Dennis E. (Intera, Inc., Austin, TX); Shirah, Donald N.

    2005-01-01

    This report documents the results of an LDRD program entitled 'System of Systems Modeling and Analysis' that was conducted during FY 2003 and FY 2004. Systems that themselves consist of multiple systems (referred to here as System of Systems or SoS) introduce a level of complexity to systems performance analysis and optimization that is not readily addressable by existing capabilities. The objective of the 'System of Systems Modeling and Analysis' project was to develop an integrated modeling and simulation environment that addresses the complex SoS modeling and analysis needs. The approach to meeting this objective involved two key efforts. First, a static analysis approach, called state modeling, has been developed that is useful for analyzing the average performance of systems over defined use conditions. The state modeling capability supports analysis and optimization of multiple systems and multiple performance measures or measures of effectiveness. The second effort involves time simulation which represents every system in the simulation using an encapsulated state model (State Model Object or SMO). The time simulation can analyze any number of systems including cross-platform dependencies and a detailed treatment of the logistics required to support the systems in a defined mission.

  13. Thermal analysis of GFRP-reinforced continuous concrete decks subjected to top fire

    National Research Council Canada - National Science Library

    Hawileh, Rami A; Rasheed, Hayder A

    2017-01-01

    ...) bars subjected to top surface fire. A finite element (FE) model is developed and a detailed transient thermal analysis is performed on a continuous concrete bridge deck under the effect of various fire curves...

  14. Bounding the Failure Probability Range of Polynomial Systems Subject to P-box Uncertainties

    Science.gov (United States)

    Crespo, Luis G.; Kenny, Sean P.; Giesy, Daniel P.

    2012-01-01

    This paper proposes a reliability analysis framework for systems subject to multiple design requirements that depend polynomially on the uncertainty. Uncertainty is prescribed by probability boxes, also known as p-boxes, whose distribution functions have free or fixed functional forms. An approach based on the Bernstein expansion of polynomials and optimization is proposed. In particular, we search for the elements of a multi-dimensional p-box that minimize (i.e., the best-case) and maximize (i.e., the worst-case) the probability of inner and outer bounding sets of the failure domain. This technique yields intervals that bound the range of failure probabilities. The offset between this bounding interval and the actual failure probability range can be made arbitrarily tight with additional computational effort.

  15. A subject-specific framework for in vivo myeloarchitectonic analysis using high resolution quantitative MRI.

    Science.gov (United States)

    Waehnert, Miriam D; Dinse, Juliane; Schäfer, Andreas; Geyer, Stefan; Bazin, Pierre-Louis; Turner, Robert; Tardif, Christine Lucas

    2016-01-15

    Structural magnetic resonance imaging can now resolve laminar features within the cerebral cortex in vivo. A variety of intracortical contrasts have been used to study the cortical myeloarchitecture with the purpose of mapping cortical areas in individual subjects. In this article, we first briefly review recent advances in MRI analysis of cortical microstructure to portray the potential and limitations of the current state-of-the-art. We then present an integrated framework for the analysis of intracortical structure, composed of novel image processing tools designed for high resolution cortical images. The main features of our framework are the segmentation of quantitative T1 maps to delineate the cortical boundaries (Bazin et al., 2014), and the use of an equivolume layering model to define an intracortical coordinate system that follows the anatomical layers of the cortex (Waehnert et al., 2014). We evaluate the framework with 150μm isotropic post mortem T2(∗)-weighted images and 0.5mm isotropic in vivo T1 maps, a quantitative index of myelin content. We study the laminar structure of the primary visual cortex (Brodmann area 17) in the post mortem and in vivo data, as well as the central sulcus region in vivo, in particular Brodmann areas 1, 3b and 4. We also investigate the impact of the layering models on the relationship between T1 and cortical curvature. Our experiments demonstrate that the equivolume intracortical surfaces and transcortical profiles best reflect the laminar structure of the cortex in areas of curvature in comparison to the state-of-the-art equidistant and Laplace implementations. This framework generates a subject specific intracortical coordinate system, the basis for subsequent architectonic analyses of the cortex. Any structural or functional contrast co-registered to the T1 maps, used to segment the cortex, can be sampled on the curved grid for analysis. This work represents an important step towards in vivo structural brain mapping

  16. Logical analysis of biological systems

    DEFF Research Database (Denmark)

    Mardare, Radu Iulian

    2005-01-01

    R. Mardare, Logical analysis of biological systems. Fundamenta Informaticae, N 64:271-285, 2005.......R. Mardare, Logical analysis of biological systems. Fundamenta Informaticae, N 64:271-285, 2005....

  17. The Subject Component of the System of Prevention of Children’s Addictive Behavior

    Directory of Open Access Journals (Sweden)

    Hanna D. Zolotova

    2014-06-01

    Full Text Available The subjects of the system of prevention of children’s addictive behavior include leading, accompanying, and mediated subjects. The macrolevel subjects are gromadas (units of local government and their leadership, institutions of higher learning that prepare social pedagogues, institutes of post-diploma education, the Center of Social Services for Families, Children, and Youth, and social service non-governmental organizations. The mesolevel subjects are institutions of learning and out-of-school and specialized institutions. The microlevel subjects are social pedagogues, form masters, curators, instructors, social workers, and children volunteers. The leading subject of social-pedagogical influence is the social pedagogue, who must act as a conscientious carrier of the idea of renouncing addictions.

  18. Directional migration and transcriptional analysis of oligodendrocyte precursors subjected to stimulation of electrical signal.

    Science.gov (United States)

    Li, Yongchao; Wang, Xinkun; Yao, Li

    2015-10-15

    Loss of oligodendrocytes as the result of central nervous system disease causes demyelination that impairs axon function. Effective directional migration of endogenous or grafted oligodendrocyte precursor cells (OPCs) to a lesion is crucial in the neural remyelination process. In this study, the migration of OPCs in electric fields (EFs) was investigated. We found that OPCs migrated anodally in applied EFs, and the directedness and displacement of anodal migration increased significantly when the EF strength increased from 50 to 200 mV/mm. However, EFs did not significantly affect the cell migration speed. The transcriptome of OPCs subjected to EF stimulation (100 and 200 mV/mm) was analyzed using RNA sequencing (RNA-Seq), and results were verified by the reverse transcription quantitative polymerase chain reaction. A Kyoto Encyclopedia of Genes and Genomes pathway analysis revealed that the mitogen-activated protein kinase pathway that signals cell migration was significantly upregulated in cells treated with an EF of 200 mV/mm compared with control cells. Gene ontology enrichment analysis showed the downregulation of differentially expressed genes in chemotaxis. This study suggests that an applied EF is an effective cue to guiding OPC migration in neural regeneration and that transcriptional analysis contributes to the understanding of the mechanism of EF-guided cell migration. Copyright © 2015 the American Physiological Society.

  19. Generalized Accelerated Failure Time Frailty Model for Systems Subject to Imperfect Preventive Maintenance

    Directory of Open Access Journals (Sweden)

    Huilin Yin

    2015-01-01

    Full Text Available Imperfect preventive maintenance (PM activities are very common in industrial systems. For condition-based maintenance (CBM, it is necessary to model the failure likelihood of systems subject to imperfect PM activities. In this paper, the models in the field of survival analysis are introduced into CBM. Namely, the generalized accelerated failure time (AFT frailty model is investigated to model the failure likelihood of industrial systems. Further, on the basis of the traditional maximum likelihood (ML estimation and expectation maximization (EM algorithm, the hybrid ML-EM algorithm is investigated for the estimation of parameters. The hybrid iterative estimation procedure is analyzed in detail. In the evaluation experiment, the generated data of a typical degradation model are verified to be appropriate for the real industrial processes with imperfect PM activities. The estimates of the model parameters are calculated using the training data. Then, the performance of the model is analyzed through the prediction of remaining useful life (RUL using the testing data. Finally, comparison between the results of the proposed model and the existing model verifies the effectiveness of the generalized AFT frailty model.

  20. Comparison of multi-subject ICA methods for analysis of fMRI data.

    Science.gov (United States)

    Erhardt, Erik Barry; Rachakonda, Srinivas; Bedrick, Edward J; Allen, Elena A; Adali, Tülay; Calhoun, Vince D

    2011-12-01

    Spatial independent component analysis (ICA) applied to functional magnetic resonance imaging (fMRI) data identifies functionally connected networks by estimating spatially independent patterns from their linearly mixed fMRI signals. Several multi-subject ICA approaches estimating subject-specific time courses (TCs) and spatial maps (SMs) have been developed, however, there has not yet been a full comparison of the implications of their use. Here, we provide extensive comparisons of four multi-subject ICA approaches in combination with data reduction methods for simulated and fMRI task data. For multi-subject ICA, the data first undergo reduction at the subject and group levels using principal component analysis (PCA). Comparisons of subject-specific, spatial concatenation, and group data mean subject-level reduction strategies using PCA and probabilistic PCA (PPCA) show that computationally intensive PPCA is equivalent to PCA, and that subject-specific and group data mean subject-level PCA are preferred because of well-estimated TCs and SMs. Second, aggregate independent components are estimated using either noise-free ICA or probabilistic ICA (PICA). Third, subject-specific SMs and TCs are estimated using back-reconstruction. We compare several direct group ICA (GICA) back-reconstruction approaches (GICA1-GICA3) and an indirect back-reconstruction approach, spatio-temporal regression (STR, or dual regression). Results show the earlier group ICA (GICA1) approximates STR, however STR has contradictory assumptions and may show mixed-component artifacts in estimated SMs. Our evidence-based recommendation is to use GICA3, introduced here, with subject-specific PCA and noise-free ICA, providing the most robust and accurate estimated SMs and TCs in addition to offering an intuitive interpretation. Copyright © 2010 Wiley Periodicals, Inc.

  1. A Subject-Specificity Analysis of Radio Channels in Wireless Body Area Networks

    Directory of Open Access Journals (Sweden)

    Yang Hao

    2011-07-01

    Full Text Available This paper presents an analysis of subject-specific radio channels in wireless body area networks (WBANs using a simulation tool based on the parallel finite-difference time-domain (FDTD technique. This technique is well suited to model radio propagations around complex, inhomogeneous objects such as the human body. The impacts of different subjects varying in size on on-body, inter-body, and off-body radio channels are studied. The analysis demonstrates that the characteristics of on-body radio channels are subject-specific and are associated with human gender, height, and body mass index. On the other hand, when waves propagate away from the body, such as in the inter-body and off-body cases, the impacts of different subjects on the channel characteristics are found to be negligible.

  2. Review Essay: Faltering Forms Go to School. Analysis of the Subject in Connection With Andreas Reckwitz

    Directory of Open Access Journals (Sweden)

    Johannes Twardella

    2009-03-01

    Full Text Available In his book "Subjectivity," Andreas RECKWITZ interprets the work of a series of structuralist and poststructuralist authors in relation to the analysis of subjectivity. In the following article I reconstruct this interpretation and attempt to critically analyze the empirical explanatory power of these authors. An excerpt from the school routine of a German class is used to show how these various "subject-theoretical analysis strategies" may lead to different, interesting, and insightful interpretations. It also becomes clear that the idea of subjectivity, and therefore of education and maturity, cannot be abandoned. Without this idea, the application of pedagogy would be cynical, and the ability to understand it impossible. URN: urn:nbn:de:0114-fqs090222

  3. Decentralized stabilization of linear time invariant systems subject to actuator saturation

    NARCIS (Netherlands)

    Stoorvogel, Antonie Arij; Saberi, Ali; Deliu, Ciprian; Deliu, C.; Sannuti, Peddapullaiah; Tarbouriech, S.; Garcia, G.; Glattfelder, A.H.

    2007-01-01

    We are concerned here with the stabilization of a linear time invariant system subject to actuator saturation via decentralized control while using linear time invariant dynamic controllers. When there exists no actuator saturation, i.e. when we consider just linear time invariant systems, it is

  4. A Framework for Control System Design Subject to Average Data-Rate Constraints

    DEFF Research Database (Denmark)

    Silva, Eduardo; Derpich, Milan; Østergaard, Jan

    2011-01-01

    This paper studies discrete-time control systems subject to average data-rate limits. We focus on a situation where a noisy linear system has been designed assuming transparent feedback and, due to implementation constraints, a source-coding scheme (with unity signal transfer function) has to be ...

  5. Semi-global stabilization of linear systems subject to non-right invertible constraints

    NARCIS (Netherlands)

    Saberi, Ali; Stoorvogel, Antonie Arij; Shi, Guoyong; Sannuti, Peddapullaiah

    Stabilization problems of linear systems with right invertible constraints have mostly been solved for both global and semi-global frameworks. Linear systems subject to non-right invertible constraints have completely different characteristics compared to those with right invertible constraints.

  6. Signals and transforms in linear systems analysis

    CERN Document Server

    Wasylkiwskyj, Wasyl

    2013-01-01

    Signals and Transforms in Linear Systems Analysis covers the subject of signals and transforms, particularly in the context of linear systems theory. Chapter 2 provides the theoretical background for the remainder of the text. Chapter 3 treats Fourier series and integrals. Particular attention is paid to convergence properties at step discontinuities. This includes the Gibbs phenomenon and its amelioration via the Fejer summation techniques. Special topics include modulation and analytic signal representation, Fourier transforms and analytic function theory, time-frequency analysis and frequency dispersion. Fundamentals of linear system theory for LTI analogue systems, with a brief account of time-varying systems, are covered in Chapter 4 . Discrete systems are covered in Chapters 6 and 7.  The Laplace transform treatment in Chapter 5 relies heavily on analytic function theory as does Chapter 8 on Z -transforms. The necessary background on complex variables is provided in Appendix A. This book is intended to...

  7. Comparative analysis of NK cell receptor repertoire in adults and very elderly subjects with cytomegalovirus infection.

    Science.gov (United States)

    Juárez-Vega, Guillermo; Rangel-Ramírez, Velia; Monsiváis-Urenda, Adriana; Niño-Moreno, Perla; Garcia-Sepúlveda, Christian; Noyola, Daniel E; González-Amaro, Roberto

    2017-03-01

    Human cytomegalovirus (HCMV) infection in children and young adults has been associated with changes in the innate immune system. We herein analyzed the possible effect of very long term HCMV infection on the expression of several NK cell receptors. Ninety HCMV-seropositive individuals were included and classified as young adults (n=30), elderly (n=30) and very elderly subjects (n=30). A peripheral blood sample was obtained and the expression of NK cell receptors (NKG2A, NKG2C, ILT2, CD161, KIR2DL1, KIR3DL1, and KIR3DL2) by NK and other lymphocyte subsets was assessed by flow cytometry. In addition, the frequency of the sixteen KIR genes was analyzed by polymerase chain reaction. We found a significant increase in the number of NKG2C+ NK and T cells in elderly individuals compared to young adults accompanied by an opposite trend in the number of NKG2A+ lymphocytes, and ILT2+ cells were also increased in elderly individuals. A significant increase in the levels of CD3-CD56+NKG2C+CD57+ cells was also detected in the elderly groups. Finally, KIR gene analysis revealed that the KIR genotype 2 was significantly less frequent in the elderly individuals. Our results support that long-term infection by HCMV exerts a significant progressive effect on the innate immune system. Copyright © 2017 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

  8. Vibration Analysis and Design of a Structure Subjected to Human Walking Excitations

    Directory of Open Access Journals (Sweden)

    M. Setareh

    2010-01-01

    Full Text Available Annoying building floor vibrations have become a serious serviceability issue. This is mainly due to decrease in the system mass resulting from the use of higher strength materials; use of computer-assisted design and the Load and Resistance Factor Design Method to optimize the structure based on the strength requirements; fewer partitions and more innovative designs by architects achieving long, column free spans resulting in a reduction in the natural frequency and damping. This paper provides details of the vibration analysis and design of a novel office building. Three-dimensional computer models of the structure were created and various modifications were made to the original structure, designed based on static loads, to reduce the possible excessive floor vibrations when subjected to walking excitations. Tuned mass dampers were also designed as a back-up vibration control system. A series of dynamic tests were conducted on the building floor to identify the dynamic properties of the structure and these were then used to update the original computer model. Finally, various forcing functions representing human walks and the updated computer model of the structure were used to evaluate the accuracy of the walking excitation force models to predict the structural response. Conclusions are made on the validity of each forcing function studied here.

  9. Impedance measures in analysis and characterization of multistable structures subjected to harmonic excitation

    Science.gov (United States)

    Harne, Ryan L.; Goodpaster, Benjamin A.

    2018-01-01

    Structural components susceptible to adverse, post-buckled dynamic behaviors have long challenged the success of applications requiring lightweight, slender curved structures, while researchers have begun to leverage such bistable systems in emerging applications for novel energy attenuation and shape-changing properties. To expedite development and deployment of these built-up platforms containing post-buckled constituents, efficient approaches are required to complement time-consuming full-field models in the prediction of the near- and far-from-equilibrium dynamics. This research meets the need by introducing a semi-analytical model framework to enable the characterization of steady-state responses in multi degree-of-freedom (DOF) and multistable structural systems subjected to harmonic excitation. In so doing, the pathway for assessing impedance measures is created here so as to identify how energy travels and returns within built-up multistable structures. Verified by simulations and qualitatively validated by experiments, the analysis is shown to accurately reproduce both near- and far-from-equilibrium responses including different classes of energetic snap-through dynamics that only exist in such multistable structures. A first look at the impedance measures of different dynamic regimes reveals a connection between damping in multistable structures and the sustainability of far-from-equilibrium oscillations.

  10. Optimal Service Distribution in WSN Service System Subject to Data Security Constraints

    Directory of Open Access Journals (Sweden)

    Zhao Wu

    2014-08-01

    Full Text Available Services composition technology provides a flexible approach to building Wireless Sensor Network (WSN Service Applications (WSA in a service oriented tasking system for WSN. Maintaining the data security of WSA is one of the most important goals in sensor network research. In this paper, we consider a WSN service oriented tasking system in which the WSN Services Broker (WSB, as the resource management center, can map the service request from user into a set of atom-services (AS and send them to some independent sensor nodes (SN for parallel execution. The distribution of ASs among these SNs affects the data security as well as the reliability and performance of WSA because these SNs can be of different and independent specifications. By the optimal service partition into the ASs and their distribution among SNs, the WSB can provide the maximum possible service reliability and/or expected performance subject to data security constraints. This paper proposes an algorithm of optimal service partition and distribution based on the universal generating function (UGF and the genetic algorithm (GA approach. The experimental analysis is presented to demonstrate the feasibility of the suggested algorithm.

  11. Optimal service distribution in WSN service system subject to data security constraints.

    Science.gov (United States)

    Wu, Zhao; Xiong, Naixue; Huang, Yannong; Gu, Qiong

    2014-08-04

    Services composition technology provides a flexible approach to building Wireless Sensor Network (WSN) Service Applications (WSA) in a service oriented tasking system for WSN. Maintaining the data security of WSA is one of the most important goals in sensor network research. In this paper, we consider a WSN service oriented tasking system in which the WSN Services Broker (WSB), as the resource management center, can map the service request from user into a set of atom-services (AS) and send them to some independent sensor nodes (SN) for parallel execution. The distribution of ASs among these SNs affects the data security as well as the reliability and performance of WSA because these SNs can be of different and independent specifications. By the optimal service partition into the ASs and their distribution among SNs, the WSB can provide the maximum possible service reliability and/or expected performance subject to data security constraints. This paper proposes an algorithm of optimal service partition and distribution based on the universal generating function (UGF) and the genetic algorithm (GA) approach. The experimental analysis is presented to demonstrate the feasibility of the suggested algorithm.

  12. Power system health analysis

    Energy Technology Data Exchange (ETDEWEB)

    Billinton, Roy; Fotuhi-Firuzabad, Mahmud; Aboreshaid, Saleh

    1997-01-01

    This paper presents a technique which combines both probabilistic indices and deterministic criteria to reflect the well-being of a power system. This technique permits power system planners, engineers and operators to maximize the probability of healthy operation as well as minimizing the probability of risky operation. The concept of system well-being is illustrated in this paper by application to the areas of operating reserve assessment and composite power system security evaluation.

  13. Objective and subjective whitening response of two self-directed bleaching systems.

    Science.gov (United States)

    Gerlach, Robert W; Barker, Matthew L; Sagel, Paul A

    2002-09-01

    To evaluate objective and subjective whitening responses of two marketed vital bleaching systems under intended use conditions. MATERIALSA ND METHODS: The randomized clinical trial evaluated 50 adults who received either a combination system with a 3% hydrogen peroxide bleaching gel, pre-formed dual arch tray, dentifrice and oral rinse (Rapid White), or 6% hydrogen peroxide whitening strips (Crest Whitestrips). Efficacy was assessed objectively from L*a*b* tooth color at Days 7 & 14, while subjective, first-person whitening perception was measured by questionnaire. A cumulative multinomial probability model was generated to predict subjective responses from objectively measured tooth color. At end-of-treatment, adjusted mean deltab* was -2.05 +/- 0.158 for the whitening strip group compared to -0.69 +/- 0.141 for the combination group, with these groups differing significantly (P color parameter and time point in this study. Relative to the combination system, subjects in the whitening strip group rated that product significantly (P impression. These subjective responses were correlated with objective changes in tooth color measured during treatment. When the deltab* effect was included in a cumulative multinomial probability model, deltaL*, deltaa*, and treatment were non-significant predictors. Odds ratios demonstrate that a subject had 3.3 times (1/0.3003 = 3.33) greater odds of selecting a higher whiteness rating when the value of deltab* was decreased by 1.0 unit (less yellowness). Similar results were noted for whitening satisfaction and overall impression of treatment.

  14. The Applied Behavior Analysis Research Paradigm and Single-Subject Designs in Adapted Physical Activity Research.

    Science.gov (United States)

    Haegele, Justin A; Hodge, Samuel Russell

    2015-10-01

    There are basic philosophical and paradigmatic assumptions that guide scholarly research endeavors, including the methods used and the types of questions asked. Through this article, kinesiology faculty and students with interests in adapted physical activity are encouraged to understand the basic assumptions of applied behavior analysis (ABA) methodology for conducting, analyzing, and presenting research of high quality in this paradigm. The purposes of this viewpoint paper are to present information fundamental to understanding the assumptions undergirding research methodology in ABA, describe key aspects of single-subject research designs, and discuss common research designs and data-analysis strategies used in single-subject studies.

  15. Effect of Metaboreflex on Cardiovascular System in Subjects of Metabolic Syndrome.

    Science.gov (United States)

    Dubey, Pramita; Tiwari, Sunita; Bajpai, Manish; Singh, Kalpana; Jha, Praveen

    2017-07-01

    Metaboreflex is a reflex in which muscle receptors send signals regarding metabolic (metabolites accumulation like lactic acid, potassium, adenosine) conditions of the muscles to nucleus tractus solitarius via afferent III and IV fibres to cause haemodynamic adjustments in order to regulate blood flow on the basis of the status of contracting muscle. Dysregulation in its mechanism in metabolic syndrome is demonstrated. To study the effect of metaboreflex by both isometric and rhythmic handgrip exercise on CVS parameters {Blood Pressure (BP), Cardiac Output (CO) and Systemic Vascular Resistance (SVR)} in subjects of metabolic syndrome. In this study, 27 subjects aged 25 to 45 years were enrolled after ethical clearance and proper consent. They were divided into: a) subjects without metabolic syndrome; and b) subjects with metabolic syndrome. Impedance cardiovasography was done to assess cardiac parameters (systolic and diastolic blood pressure, cardiac output, systemic vascular resistance). Pre-exercise parameters were assessed followed by isometric exercise and post-isometric exercise parameter measurement. Again after rest, rhythmic exercise was followed. Finally post exercise parameters were assessed. Student paired t-test for comparison between pre and post exercise parameters were done. Changes in diastolic BP following exercise were statistically significant in subjects without metabolic syndrome (p-value 0.01 and 0.001 following isometric and rhythmic exercise respectively). In subjects with metabolic syndrome also these changes were significant, but to a lesser extent (p-value 0.1 and 0.01 respectively for isometric and rhythmic exercise). Changes in systolic BP following exercise were statistically significant in subjects without metabolic syndrome (p-value 0.001 and 0.001 following isometric and rhythmic exercise respectively). In subjects with metabolic syndrome also these changes were significant (p-value 0.01 and 0.001 respectively for isometric and

  16. Systems analysis made simple computerbooks

    CERN Document Server

    Antill, Lyn

    1980-01-01

    Systems Analysis: Made Simple Computerbooks introduces the essential elements of information systems analysis and design and teaches basic technical skills required for the tasks involved. The book covers the aspects to the design of an information system; information systems and the organization, including the types of information processing activity and computer-based information systems; the role of the systems analyst; and the human activity system. The text also discusses information modeling, socio-technical design, man-machine interface, and the database design. Software specification

  17. A Subjective Evaluation of the Minimum Audible Channel Separation in Binaural Reproduction Systems Through Loudspeakers

    DEFF Research Database (Denmark)

    Lacouture Parodi, Yesenia; Rubak, Per

    2010-01-01

    To evaluate the performance of crosstalk cancellation systems the channel separation is usually used as parameter.  However, no systematic evaluation of the minimum audible channel separation has been found in the literature known by the authors.  This paper describes a set of subjective experime......To evaluate the performance of crosstalk cancellation systems the channel separation is usually used as parameter.  However, no systematic evaluation of the minimum audible channel separation has been found in the literature known by the authors.  This paper describes a set of subjective...

  18. Simulation and Analysis of Chain Drive Systems

    DEFF Research Database (Denmark)

    Pedersen, Sine Leergaard

    The subject of this thesis is simulation and analysis of large roller chain drive systems, such as e.g. used in marine diesel engines. The aim of developing a chain drive simulation program is to analyse dynamic phenomena of chain drive systems and investigate different design changes...... with a real tooth profile proves superior to other applied models. With this model it is possible to perform a dynamic simulation of large marine engine chain drives. Through the application of this method, it is shown that the interrelated dynamics of the elements in the chain drive system is captured...... systems other phenomena occur and therefore, a specific model of the marine engine chain drive is of interest. The research objective of the work presented in this thesis is to contribute with a novel theoretical basis for the analysis of chain drive systems, by posing and validating different...

  19. Structural behavior of SC panel subjected to impact loading using finite element analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyuk-Kee; Kim, Seung-Eock, E-mail: sekim@sejong.ac.kr

    2015-12-15

    Highlights: • Structural behavior of SC panel subjected to impact loading is evaluated using numerical analysis. • Sensitivity studies according to fracture energy and erosion value are performed. • Analysis results are compared with impact test for SC panel. - Abstract: After the terrorist attack on the World Trade Center using aircraft in New York City in 2001, safety assessments of nuclear power plant (NPP) structures subjected to impact loading have been actively performed. Since impact tests are possible for small-scale structures but not for full-scale structures, finite element (FE) analysis is necessary for a safety assessment of NPP structure. Analysis factors such as the material model of concrete and steel, strain rate effect, concrete fracture energy, and erosion value influence the analysis results. In this paper, the effect of the concrete fracture energy and the erosion in the material model of a steel-plate concrete (SC) panel subjected to the impact loading is evaluated using the commercial software LS-DYNA. The analysis results are compared with the impact test for an SC panel conducted in other research. A quarter model of an SC panel is adopted for impact analysis. The impact force–time history is applied on the SC panel. Sensitivity studies according to the fracture energy and the erosion value are performed in order to evaluate the structural behavior of SC panels.

  20. Population Pharmacokinetic Analysis of Voriconazole from a Pharmacokinetic Study with Immunocompromised Japanese Pediatric Subjects

    Science.gov (United States)

    Shoji, Satoshi; Tomono, Yoshiro; Liu, Ping

    2015-01-01

    A population pharmacokinetic (PK) analysis was conducted to characterize the voriconazole pharmacokinetic profiles in immunocompromised Japanese pediatric subjects and to compare them to those in immunocompromised non-Japanese pediatric subjects. A previously developed two-compartment pharmacokinetic model with first-order absorption and mixed linear and nonlinear elimination adequately described the voriconazole intravenous and oral data from Japanese pediatric subjects with few modifications. Bayesian priors were applied to this analysis by using the NONMEM routine NWPRI, which allowed priors for the fixed-effect parameter vector and variance matrix of the random-effect parameters to be a normal distribution and an inverse Wishart distribution, respectively. Large intersubject variabilities in oral bioavailability and voriconazole exposure were observed in these pediatric subjects. The mean oral bioavailability estimated in Japanese pediatric subjects was 73% (range, 17% to 99%), which is consistent with the reported estimates of 64% in the previous model and less than what was originally estimated for healthy adults—96%. Voriconazole exposures in Japanese pediatric subjects were generally comparable to those in non-Japanese pediatric subjects receiving the same dosing regimens, given the large intersubject variability. Consistent with the previous findings, the CYP2C19 genotyping status did not have a clinically relevant effect on voriconazole exposure in Japanese pediatric subjects, although it was identified as a covariate in the model to help explain the intersubject variability in voriconazole exposure. The CYP2C19 genotyping status alone does not warrant dose adjustment of voriconazole. No other factors besides age and weight were identified to explain the PK variability of voriconazole. PMID:25801557

  1. Systems Engineering Analysis

    Directory of Open Access Journals (Sweden)

    Alexei Serna M.

    2013-07-01

    Full Text Available The challenges proposed by the development of the new computer systems demand new guidance related to engineer´s education, because they will solve these problems. In the XXI century, system engineers must be able to integrate a number of topics and knowledge disciplines that complement that traditionally has been known as Computer Systems Engineering. We have enough software development engineers, today we need professional engineers for software integration, leaders and system architects that make the most of the technological development for the benefit of society, leaders that integrate sciences to the solutions they build and propose. In this article the current situation of Computer Systems Engineering is analyzed and is presented a theory proposing the need for modifying the approach Universities have given to these careers, to achieve the education of leader engineers according to the needs of this century.

  2. The informational subject in the contemporary context. An analysis from the epistemology of informational community identity

    Directory of Open Access Journals (Sweden)

    Miguel Angel Rendón-Rojas

    2012-04-01

    Full Text Available The Epistemology of Informational Community Identity (ECI-I is proposed as a toolbox for the analysis of informational reality within categories as contextual paradigm, informational subject and informational entity, built ex profeso for this theoretical-methodological analysis. The concepts of information user´s and informational subject are distinguished, the latest, to seek an answer from a concrete social enclave within a particular community and its interrelationships with others, to under go a process of self construction, from which specific information needs arise. And the user needs to seek concrete answer after formal questioning many facts occurring in a consumerist, unequal and alienating world. So the emphasis is put on the need for an interdisciplinary approach between social theory and library science in the study of the documentary information world of particular informational subjects, which is often marginalized and excluded

  3. Pharmacokinetic profile of armodafinil in healthy subjects: pooled analysis of data from three randomized studies.

    Science.gov (United States)

    Darwish, Mona; Kirby, Mary; Hellriegel, Edward T; Yang, Ronghua; Robertson, Philmore

    2009-01-01

    Armodafinil (R-modafinil) is the R- and longer-lasting isomer of the racemic compound modafinil, a wakefulness-promoting medication. Armodafinil is eliminated approximately three times more slowly than the S-isomer of racemic modafinil. Published studies have demonstrated the efficacy of armodafinil for treating excessive sleepiness associated with obstructive sleep apnoea, shift work disorder and narcolepsy. The objectives of this study were to describe the pharmacokinetic profile, tolerability and safety of armodafinil in healthy subjects. Pooled pharmacokinetic data from three separate randomized studies in 119 healthy subjects who received single or multiple (once daily for up to 14 days) oral doses of armodafinil ranging between 50 and 400 mg were analysed. The impact of food on the single-dose pharmacokinetic profile of armodafinil was also assessed in subjects following an overnight fast and after the consumption of a standard fatty meal. Armodafinil was readily absorbed and exhibited linear pharmacokinetics over the 50-400 mg dose range. Peak plasma concentrations were reached around 2 hours after administration in the fasted state. Food had no effect on the overall bioavailability of armodafinil; however, the peak concentration was delayed by approximately 2-4 hours. In the multiple-dose study, dose proportionality was confirmed by linear regression analyses of the log-transformed area under the plasma concentration versus time curve (AUC) and maximum plasma concentration (Cmax) values as a function of dose. After reaching the peak, plasma concentrations of armodafinil declined in a monophasic manner, with a mean elimination half-life of approximately 15 hours. Steady state appeared to be reached within 7 days. At steady state, the systemic exposure to armodafinil was 1.8 times that observed after single-dose administration. Armodafinil was generally well tolerated, the most frequent adverse events being headache, dizziness and nausea. In the present

  4. Refining Time-Activity Classification of Human Subjects Using the Global Positioning System.

    Directory of Open Access Journals (Sweden)

    Maogui Hu

    Full Text Available Detailed spatial location information is important in accurately estimating personal exposure to air pollution. Global Position System (GPS has been widely used in tracking personal paths and activities. Previous researchers have developed time-activity classification models based on GPS data, most of them were developed for specific regions. An adaptive model for time-location classification can be widely applied to air pollution studies that use GPS to track individual level time-activity patterns.Time-activity data were collected for seven days using GPS loggers and accelerometers from thirteen adult participants from Southern California under free living conditions. We developed an automated model based on random forests to classify major time-activity patterns (i.e. indoor, outdoor-static, outdoor-walking, and in-vehicle travel. Sensitivity analysis was conducted to examine the contribution of the accelerometer data and the supplemental spatial data (i.e. roadway and tax parcel data to the accuracy of time-activity classification. Our model was evaluated using both leave-one-fold-out and leave-one-subject-out methods.Maximum speeds in averaging time intervals of 7 and 5 minutes, and distance to primary highways with limited access were found to be the three most important variables in the classification model. Leave-one-fold-out cross-validation showed an overall accuracy of 99.71%. Sensitivities varied from 84.62% (outdoor walking to 99.90% (indoor. Specificities varied from 96.33% (indoor to 99.98% (outdoor static. The exclusion of accelerometer and ambient light sensor variables caused a slight loss in sensitivity for outdoor walking, but little loss in overall accuracy. However, leave-one-subject-out cross-validation showed considerable loss in sensitivity for outdoor static and outdoor walking conditions.The random forests classification model can achieve high accuracy for the four major time-activity categories. The model also

  5. Refining Time-Activity Classification of Human Subjects Using the Global Positioning System

    Science.gov (United States)

    Hu, Maogui; Li, Wei; Li, Lianfa; Houston, Douglas; Wu, Jun

    2016-01-01

    Background Detailed spatial location information is important in accurately estimating personal exposure to air pollution. Global Position System (GPS) has been widely used in tracking personal paths and activities. Previous researchers have developed time-activity classification models based on GPS data, most of them were developed for specific regions. An adaptive model for time-location classification can be widely applied to air pollution studies that use GPS to track individual level time-activity patterns. Methods Time-activity data were collected for seven days using GPS loggers and accelerometers from thirteen adult participants from Southern California under free living conditions. We developed an automated model based on random forests to classify major time-activity patterns (i.e. indoor, outdoor-static, outdoor-walking, and in-vehicle travel). Sensitivity analysis was conducted to examine the contribution of the accelerometer data and the supplemental spatial data (i.e. roadway and tax parcel data) to the accuracy of time-activity classification. Our model was evaluated using both leave-one-fold-out and leave-one-subject-out methods. Results Maximum speeds in averaging time intervals of 7 and 5 minutes, and distance to primary highways with limited access were found to be the three most important variables in the classification model. Leave-one-fold-out cross-validation showed an overall accuracy of 99.71%. Sensitivities varied from 84.62% (outdoor walking) to 99.90% (indoor). Specificities varied from 96.33% (indoor) to 99.98% (outdoor static). The exclusion of accelerometer and ambient light sensor variables caused a slight loss in sensitivity for outdoor walking, but little loss in overall accuracy. However, leave-one-subject-out cross-validation showed considerable loss in sensitivity for outdoor static and outdoor walking conditions. Conclusions The random forests classification model can achieve high accuracy for the four major time

  6. MOSI: Multimodal Corpus of Sentiment Intensity and Subjectivity Analysis in Online Opinion Videos

    OpenAIRE

    Zadeh, Amir; Zellers, Rowan; Pincus, Eli; Morency, Louis-Philippe

    2016-01-01

    People are sharing their opinions, stories and reviews through online video sharing websites every day. Studying sentiment and subjectivity in these opinion videos is experiencing a growing attention from academia and industry. While sentiment analysis has been successful for text, it is an understudied research question for videos and multimedia content. The biggest setbacks for studies in this direction are lack of a proper dataset, methodology, baselines and statistical analysis of how inf...

  7. The statistical analysis of single-subject data: a comparative examination.

    Science.gov (United States)

    Nourbakhsh, M R; Ottenbacher, K J

    1994-08-01

    The purposes of this study were to examine whether the use of three different statistical methods for analyzing single-subject data led to similar results and to identify components of graphed data that influence agreement (or disagreement) among the statistical procedures. Forty-two graphs containing single-subject data were examined. Twenty-one were AB charts of hypothetical data. The other 21 graphs appeared in Journal of Applied Behavioral Analysis, Physical Therapy, Journal of the Association for Persons With Severe Handicaps, and Journal of Behavior Therapy and Experimental Psychiatry. Three different statistical tests--the C statistic, the two-standard deviation band method, and the split-middle method of trend estimation--were used to analyze the 42 graphs. A relatively low degree of agreement (38%) was found among the three statistical tests. The highest rate of agreement for any two statistical procedures (71%) was found for the two-standard deviation band method and the C statistic. A logistic regression analysis revealed that overlap in single-subject graphed data was the best predictor of disagreement among the three statistical tests (beta = .49, P < .03). The results indicate that interpretation of data from single-subject research designs is directly influenced by the method of data analysis selected. Variation exists across both visual and statistical methods of data reduction. The advantages and disadvantages of statistical and visual analysis are described.

  8. Social Gerontology--Integrative and Territorial Aspects: A Citation Analysis of Subject Scatter and Database Coverage

    Science.gov (United States)

    Lasda Bergman, Elaine M.

    2011-01-01

    To determine the mix of resources used in social gerontology research, a citation analysis was conducted. A representative sample of citations was selected from three prominent gerontology journals and information was added to determine subject scatter and database coverage for the cited materials. Results indicate that a significant portion of…

  9. Energy Usage Analysis System

    Data.gov (United States)

    General Services Administration — The EUAS application is a web based system which serves Energy Center of Expertise, under the Office of Facilitates Management and Service Programs. EUAS is used for...

  10. Laser rocket system analysis

    Science.gov (United States)

    Jones, W. S.; Forsyth, J. B.; Skratt, J. P.

    1979-01-01

    The laser rocket systems investigated in this study were for orbital transportation using space-based, ground-based and airborne laser transmitters. The propulsion unit of these systems utilizes a continuous wave (CW) laser beam focused into a thrust chamber which initiates a plasma in the hydrogen propellant, thus heating the propellant and providing thrust through a suitably designed nozzle and expansion skirt. The specific impulse is limited only by the ability to adequately cool the thruster and the amount of laser energy entering the engine. The results of the study showed that, with advanced technology, laser rocket systems with either a space- or ground-based laser transmitter could reduce the national budget allocated to space transportation by 10 to 345 billion dollars over a 10-year life cycle when compared to advanced chemical propulsion systems (LO2-LH2) of equal capability. The variation in savings depends upon the projected mission model.

  11. Power Plant Systems Analysis

    Science.gov (United States)

    Williams, J. R.; Yang, Y. Y.

    1973-01-01

    Three basic thermodynamic cycles of advanced nuclear MHD power plant systems are studied. The effect of reactor exit temperature and space radiator temperature on the overall thermal efficiency of a regenerative turbine compressor power plant system is shown. The effect of MHD pressure ratio on plant efficiency is also described, along with the dependence of MHD power output, compressor power requirement, turbine power output, mass flow rate of H2, and overall plant efficiency on the reactor exit temperature for a specific configuration.

  12. Spherical subjective refraction with a novel 3D virtual reality based system.

    Science.gov (United States)

    Pujol, Jaume; Ondategui-Parra, Juan Carlos; Badiella, Llorenç; Otero, Carles; Vilaseca, Meritxell; Aldaba, Mikel

    To conduct a clinical validation of a virtual reality-based experimental system that is able to assess the spherical subjective refraction simplifying the methodology of ocular refraction. For the agreement assessment, spherical refraction measurements were obtained from 104 eyes of 52 subjects using three different methods: subjectively with the experimental prototype (Subj.E) and the classical subjective refraction (Subj.C); and objectively with the WAM-5500 autorefractor (WAM). To evaluate precision (intra- and inter-observer variability) of each refractive tool independently, 26 eyes were measured in four occasions. With regard to agreement, the mean difference (±SD) for the spherical equivalent (M) between the new experimental subjective method (Subj.E) and the classical subjective refraction (Subj.C) was -0.034D (±0.454D). The corresponding 95% Limits of Agreement (LoA) were (-0.856D, 0.924D). In relation to precision, intra-observer mean difference for the M component was 0.034±0.195D for the Subj.C, 0.015±0.177D for the WAM and 0.072±0.197D for the Subj.E. Inter-observer variability showed worse precision values, although still clinically valid (below 0.25D) in all instruments. The spherical equivalent obtained with the new experimental system was precise and in good agreement with the classical subjective routine. The algorithm implemented in this new system and its optical configuration has been shown to be a first valid step for spherical error correction in a semiautomated way. Copyright © 2016 Spanish General Council of Optometry. Published by Elsevier España, S.L.U. All rights reserved.

  13. Novel Method for Automated Analysis of Retinal Images: Results in Subjects with Hypertensive Retinopathy and CADASIL.

    Science.gov (United States)

    Cavallari, Michele; Stamile, Claudio; Umeton, Renato; Calimeri, Francesco; Orzi, Francesco

    2015-01-01

    Morphological analysis of the retinal vessels by fundoscopy provides noninvasive means for detecting and staging systemic microvascular damage. However, full exploitation of fundoscopy in clinical settings is limited by paucity of quantitative, objective information obtainable through the observer-driven evaluations currently employed in routine practice. Here, we report on the development of a semiautomated, computer-based method to assess retinal vessel morphology. The method allows simultaneous and operator-independent quantitative assessment of arteriole-to-venule ratio, tortuosity index, and mean fractal dimension. The method was implemented in two conditions known for being associated with retinal vessel changes: hypertensive retinopathy and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). The results showed that our approach is effective in detecting and quantifying the retinal vessel abnormalities. Arteriole-to-venule ratio, tortuosity index, and mean fractal dimension were altered in the subjects with hypertensive retinopathy or CADASIL with respect to age- and gender-matched controls. The interrater reliability was excellent for all the three indices (intraclass correlation coefficient ≥ 85%). The method represents simple and highly reproducible means for discriminating pathological conditions characterized by morphological changes of retinal vessels. The advantages of our method include simultaneous and operator-independent assessment of different parameters and improved reliability of the measurements.

  14. Novel Method for Automated Analysis of Retinal Images: Results in Subjects with Hypertensive Retinopathy and CADASIL

    Directory of Open Access Journals (Sweden)

    Michele Cavallari

    2015-01-01

    Full Text Available Morphological analysis of the retinal vessels by fundoscopy provides noninvasive means for detecting and staging systemic microvascular damage. However, full exploitation of fundoscopy in clinical settings is limited by paucity of quantitative, objective information obtainable through the observer-driven evaluations currently employed in routine practice. Here, we report on the development of a semiautomated, computer-based method to assess retinal vessel morphology. The method allows simultaneous and operator-independent quantitative assessment of arteriole-to-venule ratio, tortuosity index, and mean fractal dimension. The method was implemented in two conditions known for being associated with retinal vessel changes: hypertensive retinopathy and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL. The results showed that our approach is effective in detecting and quantifying the retinal vessel abnormalities. Arteriole-to-venule ratio, tortuosity index, and mean fractal dimension were altered in the subjects with hypertensive retinopathy or CADASIL with respect to age- and gender-matched controls. The interrater reliability was excellent for all the three indices (intraclass correlation coefficient ≥ 85%. The method represents simple and highly reproducible means for discriminating pathological conditions characterized by morphological changes of retinal vessels. The advantages of our method include simultaneous and operator-independent assessment of different parameters and improved reliability of the measurements.

  15. Photoacoustic physio-chemical analysis of liver conditions in animal and human subjects

    Science.gov (United States)

    Wang, Xueding; Xu, Guan; Tian, Chao; Wan, Shanshan; Welling, Theodore H.; Lok, Anna S. F.; Rubin, Jonathan M.

    2016-03-01

    Non-alcoholic fatty liver disease (NAFLD) is a common liver disease affecting 30% of the population in the United States. Biopsy is the gold standard for diagnosing NAFLD. Liver histology assesses the amount of fat, and determines type and extent of cell injury, inflammation and fibrosis. However, liver biopsy is invasive and is limited by sampling error. Current radiological diagnostic modalities can evaluate the 'physical' morphology in liver by quantifying the backscattered US signals, but cannot interrogate the 'histochemical' components forming these backscatterers. For example, ultrasound (US) imaging can detect the presence of fat but cannot differentiate steatosis alone from steatohepatitis. Our previous study of photoacoustic physiochemical analysis (PAPCA) has demonstrated that this method can characterize the histological changes in livers during the progression of NAFLD in animal models. In this study, we will further validate PAPCA with human livers. Ex vivo human liver samples with steatosis, fibrosis and cirrhosis will be scanned using optical illumination at wavelengths of 680-1700 nm and compared to histology results. In vivo study on human subjects with confirmed steatosis is planned using our PA-ultrasound (US) parallel imaging system based on Verasonic US imaging flatform with an L7-4 probe. 10 mJ/cm2 per pulse optical energy at 755 nm will be delivered to the skin surface, which is under the safety limit of American National Standard Institute. Preliminary study with ex vivo human tissue has demonstrated the potential of the proposed approach in differentiating human liver conditions.

  16. Two energy system analysis - cases

    DEFF Research Database (Denmark)

    Lund, Henrik; Antonoff, Jayson; Andersen, Anders N.

    2004-01-01

    The chapter presents tow cases of energy system analysis, illustrating the types of tools and methodologies presently being used for these studies in Denamrk and elsewhere.......The chapter presents tow cases of energy system analysis, illustrating the types of tools and methodologies presently being used for these studies in Denamrk and elsewhere....

  17. Exergy Analysis for Energy Systems

    Science.gov (United States)

    2006-09-01

    AFRL-VA-WP-TM-2007-3095 EXERGY ANALYSIS FOR ENERGY SYSTEMS Dr. Rama S.R. Gorla Gorla Consultants, Inc. SEPTEMBER 2006 Final...IN-HOUSE 5b. GRANT NUMBER 4. TITLE AND SUBTITLE EXERGY ANALYSIS FOR ENERGY SYSTEMS 5c. PROGRAM ELEMENT NUMBER 0602201 5d. PROJECT NUMBER

  18. Altered intestinal functions and increased local inflammation in insulin-resistant obese subjects: a gene-expression profile analysis.

    Science.gov (United States)

    Veilleux, Alain; Mayeur, Sylvain; Bérubé, Jean-Christophe; Beaulieu, Jean-François; Tremblay, Eric; Hould, Frédéric-Simon; Bossé, Yohan; Richard, Denis; Levy, Emile

    2015-09-16

    Metabolic alterations relevant to postprandial dyslipidemia were previously identified in the intestine of obese insulin-resistant subjects. The aim of the study was to identify the genes deregulated by systemic insulin resistance in the intestine of severely obese subjects. Transcripts from duodenal samples of insulin-sensitive (HOMA-IR insulin-resistant (HOMA-IR > 7, n = 9) obese subjects were assayed by microarray (Illumina HumanHT-12). A total of 195 annotated genes were identified as differentially expressed between these two groups (Fold change > 1.2). Of these genes, 36 were found to be directly involved in known intestinal functions, including digestion, extracellular matrix, endocrine system, immunity and cholesterol metabolism. Interestingly, all differentially expressed genes (n = 8) implicated in inflammation and oxidative stress were found to be upregulated in the intestine of insulin-resistant compared to insulin-sensitive subjects. Metabolic pathway analysis revealed that several signaling pathways involved in immunity and inflammation were significantly enriched in differently expressed genes and were predicted to be activated in the intestine of insulin-resistant subjects. Using stringent criteria (Fold change > 1.5; FDR insulin-resistant compared to insulin-sensitive subjects: the transcripts of the insulinotropic glucose-dependant peptide (GIP) and of the β-microseminoprotein (MSMB) were significantly reduced, but that of the humanin like-1 (MTRNR2L1) was significantly increased. These results underline that systemic insulin resistance is associated with remodeling of key intestinal functions. Moreover, these data indicate that small intestine metabolic dysfunction is accompanied with a local amplification of low-grade inflammatory process implicating several pathways. Genes identified in this study are potentially triggered throughout the development of intestinal metabolic abnormalities, which could contribute to

  19. Medication adherence interventions that target subjects with adherence problems: Systematic review and meta-analysis.

    Science.gov (United States)

    Conn, Vicki S; Ruppar, Todd M; Enriquez, Maithe; Cooper, Pam

    2016-01-01

    Inadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication adherence have targeted adults with adherence problems. No previous reviews have synthesized the effectiveness of medication adherence interventions focused on subjects with medication adherence difficulties. This systematic review and meta-analysis synthesized findings from medication adherence intervention studies conducted among adults with medication adherence difficulties. Primary research studies were eligible for inclusion if they tested an intervention designed to increase medication adherence among adults with documented adherence difficulties and reported medication adherence behavior outcomes. Comprehensive search strategies of 13 computerized databases, author and ancestry searches, and hand searches of 57 journals were used to locate eligible primary research. Participant demographics, intervention characteristics, and methodological features were reliably coded from reports along with medication adherence outcomes. Effect sizes for outcomes were calculated as standardized mean differences, and random effects models were used to estimate overall mean effects. Exploratory dichotomous and continuous variable moderator analyses were employed to examine potential associations between medication adherence effect size and sample, intervention, and methodological characteristics. Data were extracted from 53 reports of studies involving 8243 individual primary study participants. The overall standardized mean difference effect size for treatment vs. control subjects was 0.301. For treatment pre- vs. post-intervention comparisons, the overall effect size was 0.533. Significantly larger effect sizes were associated with interventions incorporating prompts to take medications than interventions lacking medication prompts (0.497 vs. 0.234). Larger effect sizes were also found for interventions that linked

  20. Medication Adherence Interventions That Target Subjects with Adherence Problems: Systematic Review and Meta-analysis

    Science.gov (United States)

    Conn, Vicki S.; Ruppar, Todd M.; Enriquez, Maithe; Cooper, Pam

    2015-01-01

    Background Inadequate medication adherence is a pervasive, under-recognized cause of poor health outcomes. Many intervention trials designed to improve medication adherence have targeted adults with adherence problems. No previous reviews have synthesized the effectiveness of medication adherence interventions focused on subjects with medication adherence difficulties. Objective This systematic review and meta-analysis synthesized findings from medication adherence intervention studies conducted among adults with medication adherence difficulties. Methods Primary research studies were eligible for inclusion if they tested an intervention designed to increase medication adherence among adults with documented adherence difficulties and reported medication adherence behavior outcomes. Comprehensive search strategies of 13 computerized databases, author and ancestry searches, and hand searches of 57 journals were used to locate eligible primary research. Participant demographics, intervention characteristics, and methodological features were reliably coded from reports along with medication adherence outcomes. Effect sizes for outcomes were calculated as standardized mean differences, and random effects models were used to estimate overall mean effects. Exploratory dichotomous and continuous variable moderator analyses were employed to examine potential associations between medication adherence effect size and sample, intervention, and methodological characteristics. Results Data were extracted from 53 reports of studies involving 8,243 individual primary study participants. The overall standardized mean difference effect size for treatment vs. control subjects was 0.301. For treatment pre- vs. post-intervention comparisons, the overall effect size was 0.533. Significantly larger effect sizes were associated with interventions incorporating prompts to take medications than interventions lacking medication prompts (0.497 vs. 0.234). Larger effect sizes were also found

  1. INNOVATIVE ACTIVITY OF BANK SYSTEM SUBJECTS AS A FORM OF REALIZATION OF ECONOMIC INTERESTS

    Directory of Open Access Journals (Sweden)

    T. Ya. Krasnoperova

    2013-01-01

    Full Text Available The article deals with the actual problem for innovative development of the Russian Federation banking system as form of economic interests realization.Ways of innovative activity stirring up by coordination of economic interests for bank activity subjects are offered.

  2. Semi-global stabilization of linear systems subject to non-right invertible constraints

    NARCIS (Netherlands)

    Saberi, Ali; Stoorvogel, Antonie Arij; Shi, Guoyong; Sannuti, Peddapullaiah

    Much progress has been made for the stabilization of linear systems subject to constraints. This paper summarizes the results established along the line of constraints modeled by a constrained output. Stabilization results established earlier for right invertible constraints are reviewed. New

  3. State-Feedback Control for Fractional-Order Nonlinear Systems Subject to Input Saturation

    Directory of Open Access Journals (Sweden)

    Junhai Luo

    2014-01-01

    Full Text Available We give a state-feedback control method for fractional-order nonlinear systems subject to input saturation. First, a sufficient condition is derived for the asymptotical stability of a class of fractional-order nonlinear systems. Then based on Gronwall-Bellman lemma and a sector bounded condition of the saturation function, a linear state-feed back controller is designed. Finally, two simulation examples are presented to show the validity of the proposed method.

  4. Resistance of Concrete Masonry Walls With Membrane Catcher Systems Subjected to Blast Loading

    Science.gov (United States)

    2010-12-01

    are made. sandwich panel, prestressed concrete , composite, test, explosive load U U U UU 22 Paul Sheppard Reset 1 Resistance of...AFRL-RX-TY-TP-2010-0090 RESISTANCE OF CONCRETE MASONRY WALLS WITH MEMBRANE CATCHER SYSTEMS SUBJECTED TO BLAST LOADING...Include area code) 29-DEC-2010 Refereed Journal Article 01-OCT-2008 -- 31-DEC-2009 Resistance of Concrete Masonry Walls With Membrane Catcher Systems

  5. Integrated system reliability analysis

    DEFF Research Database (Denmark)

    Gintautas, Tomas; Sørensen, John Dalsgaard

    Specific targets: 1) The report shall describe the state of the art of reliability and risk-based assessment of wind turbine components. 2) Development of methodology for reliability and risk-based assessment of the wind turbine at system level. 3) Describe quantitative and qualitative measures...... (indicators) that can be used to assess the reliability of innovations and new technologies....

  6. Multilevel meta-analysis of single-subject experimental designs: a simulation study.

    Science.gov (United States)

    Ugille, Maaike; Moeyaert, Mariola; Beretvas, S Natasha; Ferron, John; Van den Noortgate, Wim

    2012-12-01

    One way to combine data from single-subject experimental design studies is by performing a multilevel meta-analysis, with unstandardized or standardized regression coefficients as the effect size metrics. This study evaluates the performance of this approach. The results indicate that a multilevel meta-analysis of unstandardized effect sizes results in good estimates of the effect. The multilevel meta-analysis of standardized effect sizes, on the other hand, is suitable only when the number of measurement occasions for each subject is 20 or more. The effect of the treatment on the intercept is estimated with enough power when the studies are homogeneous or when the number of studies is large; the power of the effect on the slope is estimated with enough power only when the number of studies and the number of measurement occasions are large.

  7. The response of endocrine system to stress loads during space flight in human subject

    Science.gov (United States)

    Macho, L.; Koška, J.; Kšinantová, L.; Pacak, K.; Hoff, T.; Noskov, V. B.; Grigoriev, A. I.; Vigaš, M.; Kvetňanský, R.

    The responses of endocrine system to the exposure to stress-work load and hormonal changes during oral glucose tolerance tests were studied in the Slovak astronaut before (three weeks before flight), during (on the 4th and the 6th days of space flight), and after space flight (1-3 days and 15-17 days after space flight) on board of space station MIR. Blood samples during the tests were collected via cannula inserted into cubital vein, centrifuged in the special appliance Plasma-03, frozen in Kryogem-03, and at the end of the 8-day space flight transforred to Earth in special container for hormonal analysis. Preflight workload produced an increase of plasma norepinephrine and a moderate elevation of epinephrine levels. Plasma levels of insulin, growth hormone, prolactin and cortisol were not markedly changed immediately or 10 min after the end of work load. The higher increases of plasma growth hormone, prolactin and catecholamine levels were noted after workload during space flight as compared to preflight response. The higher plasma glucose and insulin levels were noted during the oral glucose tolerance test in space flight and also in the post flight period. Plasma epinephrine levels were slightly decreasing during glucose tolerance test; however, plasma norepinephrine levels were not changed. The similar patterns of catecholamine levels during glucose tolerance test were found when compared the preflight, in-flight and post flight values. These data demonstrate the changes of the dynamic responses of endocrine system to stress-work and metabolic loads during space flight in human subject.

  8. Multichannel SQUID system for measurement of spinal cord evoked magnetic field for supine subjects

    Energy Technology Data Exchange (ETDEWEB)

    Adachi, Y; Kawai, J; Miyamoto, M; Uehara, G; Ogata, H [Applied Electronics Laboratory, Kanazawa Institute of Technology, 3 Amaike, Kanazawa, Ishikawa, 920-1331 (Japan); Kawabata, S [Section of Orthopaedic and Spinal Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519 (Japan)

    2008-02-01

    A SQUID biomagnetometer system for cervical spinal cord evoked field (SCEF) was developed to investigate a non-invasive diagnosis of function of the spinal cord. The measurement system was characterized by a uniquely shaped cryostat designed for supine subjects. The cryostat has a vertical cylindrical main body whose dimensions are 500 mm in diameter and 940 mm in height and a horizontal protrusion from the side surface with 390 mm of length. The sensor array of 35 LTS-SQUID vector gradiometers directed vertically upward is installed in the end of the protruded part. Subjects lie on a bed in supine position with the head running off the edge of the bed and the back of the neck supported on the upper surface of the protruded part of the cryostat standing beside the bed. This structure readily enables the sensor array to approach close to the neck of the supine subject. The subjects can keep their posture stable during the measurement. We demonstrated the cervical SCEF was successfully detected from a healthy subject who was given electric stimulation to the median nerve at the wrist. The intensity of the evoked magnetic field was 40-70 fT in amplitude. The neural signal propagating along the spinal cord was magnetically observed from the investigation of the transition of the magnetic field distribution.

  9. Performance evaluation method of electric energy data acquire system based on combination of subjective and objective weights

    Science.gov (United States)

    Gao, Chen; Ding, Zhongan; Deng, Bofa; Yan, Shengteng

    2017-10-01

    According to the characteristics of electric energy data acquire system (EEDAS), considering the availability of each index data and the connection between the index integrity, establishing the performance evaluation index system of electric energy data acquire system from three aspects as master station system, communication channel, terminal equipment. To determine the comprehensive weight of each index based on triangular fuzzy number analytic hierarchy process with entropy weight method, and both subjective preference and objective attribute are taken into consideration, thus realize the performance comprehensive evaluation more reasonable and reliable. Example analysis shows that, by combination with analytic hierarchy process (AHP) and triangle fuzzy numbers (TFN) to establish comprehensive index evaluation system based on entropy method, the evaluation results not only convenient and practical, but also more objective and accurate.

  10. Joint fMRI analysis and subject clustering using sparse dictionary learning

    Science.gov (United States)

    Kim, Seung-Jun; Dontaraju, Krishna K.

    2017-08-01

    Multi-subject fMRI data analysis methods based on sparse dictionary learning are proposed. In addition to identifying the component spatial maps by exploiting the sparsity of the maps, clusters of the subjects are learned by postulating that the fMRI volumes admit a subspace clustering structure. Furthermore, in order to tune the associated hyper-parameters systematically, a cross-validation strategy is developed based on entry-wise sampling of the fMRI dataset. Efficient algorithms for solving the proposed constrained dictionary learning formulations are developed. Numerical tests performed on synthetic fMRI data show promising results and provides insights into the proposed technique.

  11. Non-linear canonical correlation for joint analysis of MEG signals from two subjects

    Directory of Open Access Journals (Sweden)

    Cristina eCampi

    2013-06-01

    Full Text Available We consider the problem of analysing magnetoencephalography (MEG data measured from two persons undergoing the same experiment, and we propose a method that searches for sources with maximally correlated energies. Our method is based on canonical correlation analysis (CCA, which provides linear transformations, one for each subject, such that the correlation between the transformed MEG signals is maximized. Here, we present a nonlinear version of CCA which measures the correlation of energies. Furthermore, we introduce a delay parameter in the modelto analyse, e.g., leader-follower changes in experiments where the two subjects are engaged in social interaction.

  12. Exergy Analysis of Rocket Systems

    Science.gov (United States)

    Gilbert, Andrew; Mesmer, Bryan; Watson, Michael D.

    2015-01-01

    Exergy is defined as the useful work available from a system in a specified environment. Exergy analysis allows for comparison between different system designs, and allows for comparison of subsystem efficiencies within system designs. The proposed paper explores the relationship between the fundamental rocket equation and an exergy balance equation. A previously derived exergy equation related to rocket systems is investigated, and a higher fidelity analysis will be derived. The exergy assessments will enable informed, value-based decision making when comparing alternative rocket system designs, and will allow the most efficient configuration among candidate configurations to be determined.

  13. Estimation of first excursion probability for mechanical appendage system subjected to nonstationary earthquake excitation

    Energy Technology Data Exchange (ETDEWEB)

    Aoki, Shigeru; Suzuki, Kohei (Tokyo Metropolitan Univ. (Japan))

    1984-06-01

    An estimation technique whereby the first excursion probability of the mechanical appendage system subjected to the nonstationary seismic excitation can be conventionally calculated is proposed. The first excursion probability of the appendage system is estimated by using this method and the following results are obtained. (1) The probability from this technique is more convervative than that from a simulation technique taking artificial time histories compatible to the design spectrum as input excitation. (2) The first excursion probability is practically independent of the natural period of the appendage system when the tolerable barrier level is normalized by the response amplification factor given by the design spectrum. (3) The first excursion probability decreases as the damping ratio of the appendage system increases. It also decreases as the mass ratio of the appendage system to the supporting system increases. (4) For the inelastic appendage system, the first excursion probability is reduced, if an appropriate elongation is permitted.

  14. Arctic Climate Systems Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ivey, Mark D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Robinson, David G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Boslough, Mark B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Backus, George A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Peterson, Kara J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); van Bloemen Waanders, Bart G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Swiler, Laura Painton [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Desilets, Darin Maurice [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Reinert, Rhonda Karen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-01

    This study began with a challenge from program area managers at Sandia National Laboratories to technical staff in the energy, climate, and infrastructure security areas: apply a systems-level perspective to existing science and technology program areas in order to determine technology gaps, identify new technical capabilities at Sandia that could be applied to these areas, and identify opportunities for innovation. The Arctic was selected as one of these areas for systems level analyses, and this report documents the results. In this study, an emphasis was placed on the arctic atmosphere since Sandia has been active in atmospheric research in the Arctic since 1997. This study begins with a discussion of the challenges and benefits of analyzing the Arctic as a system. It goes on to discuss current and future needs of the defense, scientific, energy, and intelligence communities for more comprehensive data products related to the Arctic; assess the current state of atmospheric measurement resources available for the Arctic; and explain how the capabilities at Sandia National Laboratories can be used to address the identified technological, data, and modeling needs of the defense, scientific, energy, and intelligence communities for Arctic support.

  15. Safety Analysis of Dual Purpose Metal Cask Subjected to Impulsive Loads due to Aircraft Engine Crash

    Science.gov (United States)

    Shirai, Koji; Namba, Kosuke; Saegusa, Toshiari

    In Japan, the first Interim Storage Facility of spent nuclear fuel away from reactor site is being planned to start its commercial operation around 2010, in use of dual-purpose metal cask in the northern part of Main Japan Island. Business License Examination for safety design approval has started since March, 2007. To demonstrate the more scientific and rational performance of safety regulation activities on each phase for the first license procedure, CREPEI has executed demonstration tests with full scale casks, such as drop tests onto real targets without impact limiters(1) and seismic tests subjected to strong earthquake motions(2). Moreover, it is important to develop the knowledge for the inherent security of metal casks under extreme mechanical-impact conditions, especially for increasing interest since the terrorist attacks from 11th September 2001(3)-(6). This paper presents dynamic mechanical behavior of the metal cask lid closure system caused by direct aircraft engine crash and describes calculated results (especially, leak tightness based on relative dynamic displacements between metallic seals). Firstly, the local penetration damage of the interim storage facility building by a big passenger aircraft engine crash (diameter 2.7m, length 4.3m, weight 4.4ton, impact velocity 90m/s) has been examined. The reduced velocity is calculated by the local damage formula for concrete structure with its thickness of 70cm. The load vs. time function for this reduced velocity (60m/s) is estimated by the impact analysis using Finite Element code LS-DYNA with the full scale engine model onto a hypothetically rigid target. Secondly, as the most critical scenarios for the metal cask, two impact scenarios (horizontal impact hitting the cask and vertical impact onto the lid metallic seal system) are chosen. To consider the geometry of all bolts for two lids, the gasket reaction forces and the inner pressure of the cask cavity, the detailed three dimensional FEM models are

  16. Comparative Analysis of the Reliability of Steel Structure with Pinned and Rigid Nodes Subjected to Fire

    Science.gov (United States)

    Kubicka, Katarzyna; Radoń, Urszula; Szaniec, Waldemar; Pawlak, Urszula

    2017-10-01

    The paper concerns the reliability analysis of steel structures subjected to high temperatures of fire gases. Two types of spatial structures were analysed, namely with pinned and rigid nodes. The fire analysis was carried out according to prescriptions of Eurocode. The static-strength analysis was conducted using the finite element method (FEM). The MES3D program, developed by Szaniec (Kielce University of Technology, Poland), was used for this purpose. The results received from MES3D made it possible to carry out the reliability analysis using the Numpress Explore program that was developed at the Institute of Fundamental Technological Research of the Polish Academy of Sciences [9]. The measurement of reliability of structures is the Hasofer-Lind reliability index (β). The reliability analysis was carried out according to approximation (FORM, SORM) and simulation (Importance Sampling, Monte Carlo) methods. As the fire progresses, the value of reliability index decreases. The analysis conducted for the study made it possible to evaluate the impact of node types on those changes. In real structures, it is often difficult to define correctly types of nodes, so some simplifications are made. The presented analysis contributes to the recognition of consequences of such assumptions for the safety of structures, subjected to fire.

  17. The impact of different 18FDG PET healthy subject scans for comparison with single patient in SPM analysis.

    Science.gov (United States)

    Gallivanone, Francesca; Della Rosa, Pasquale A; Perani, Daniela; Gilardi, Maria C; Castiglioni, Isabella

    2017-03-01

    Statistical Parametric Mapping (SPM) has been applied for single-subject evaluation of [18F]FDG uptake in Alzheimer Disease (AD). In a single-subject framework, the patient is compared to a dataset of [18F]FDG PET images from healthy subjects (HS) evaluating brain metabolic abnormalities. No studies exist that assess the effects on SPM analysis of HS [18F]FDG PET datasets acquired from different subjects and using different PET scanners including the same or different PET scanners than those used for patients. This work aims to elucidate this issue from a methodological perspective. We considered six different [18F]FDG PET datasets, from different HS populations, acquired by different PET scanners. We applied SPM5 procedures for single-subject comparison with each of the six HS datasets in 10 probable AD patients showing the typical [18F]FDG pattern. We also implemented the same comparison in 3 probable AD patients and in 7 patients with a clinical diagnosis of Mild Cognitive Impariment (MCI), showing subtle changes on visual inspection of [18F]FDG distribution. Considering the 10 patients with the typical [18F]FDG pattern, the results were comparable for all the SPM maps. In the 3 probable AD patients with subtle changes in [18F]FDG distribution, no significant AD pattern emerged when a small number (50) HS image set was used. In the 7 considered MCI patients the use of a large (>50) HS image set allowed to assess significant hypometabolic patterns related to a probable neurodegenerative pathology. The use of large HS datasets of PET scans (>50) is recommended for single-subject SPM analysis. On condition that appropriate preprocessing steps are provided, large HS datasets can include HS images acquired with different PET systems, not including images from the same scanner of that used for patients.

  18. Optimizing preprocessing and analysis pipelines for single-subject fMRI: 2. Interactions with ICA, PCA, task contrast and inter-subject heterogeneity.

    Science.gov (United States)

    Churchill, Nathan W; Yourganov, Grigori; Oder, Anita; Tam, Fred; Graham, Simon J; Strother, Stephen C

    2012-01-01

    A variety of preprocessing techniques are available to correct subject-dependant artifacts in fMRI, caused by head motion and physiological noise. Although it has been established that the chosen preprocessing steps (or "pipeline") may significantly affect fMRI results, it is not well understood how preprocessing choices interact with other parts of the fMRI experimental design. In this study, we examine how two experimental factors interact with preprocessing: between-subject heterogeneity, and strength of task contrast. Two levels of cognitive contrast were examined in an fMRI adaptation of the Trail-Making Test, with data from young, healthy adults. The importance of standard preprocessing with motion correction, physiological noise correction, motion parameter regression and temporal detrending were examined for the two task contrasts. We also tested subspace estimation using Principal Component Analysis (PCA), and Independent Component Analysis (ICA). Results were obtained for Penalized Discriminant Analysis, and model performance quantified with reproducibility (R) and prediction metrics (P). Simulation methods were also used to test for potential biases from individual-subject optimization. Our results demonstrate that (1) individual pipeline optimization is not significantly more biased than fixed preprocessing. In addition, (2) when applying a fixed pipeline across all subjects, the task contrast significantly affects pipeline performance; in particular, the effects of PCA and ICA models vary with contrast, and are not by themselves optimal preprocessing steps. Also, (3) selecting the optimal pipeline for each subject improves within-subject (P,R) and between-subject overlap, with the weaker cognitive contrast being more sensitive to pipeline optimization. These results demonstrate that sensitivity of fMRI results is influenced not only by preprocessing choices, but also by interactions with other experimental design factors. This paper outlines a

  19. Systems analysis-independent analysis and verification

    Energy Technology Data Exchange (ETDEWEB)

    Badin, J.S.; DiPietro, J.P. [Energetics, Inc., Columbia, MD (United States)

    1995-09-01

    The DOE Hydrogen Program is supporting research, development, and demonstration activities to overcome the barriers to the integration of hydrogen into the Nation`s energy infrastructure. Much work is required to gain acceptance of hydrogen energy system concepts and to develop them for implementation. A systems analysis database has been created that includes a formal documentation of technology characterization profiles and cost and performance information. Through a systematic and quantitative approach, system developers can understand and address important issues and thereby assure effective and timely commercial implementation. This project builds upon and expands the previously developed and tested pathway model and provides the basis for a consistent and objective analysis of all hydrogen energy concepts considered by the DOE Hydrogen Program Manager. This project can greatly accelerate the development of a system by minimizing the risk of costly design evolutions, and by stimulating discussions, feedback, and coordination of key players and allows them to assess the analysis, evaluate the trade-offs, and to address any emerging problem areas. Specific analytical studies will result in the validation of the competitive feasibility of the proposed system and identify system development needs. Systems that are investigated include hydrogen bromine electrolysis, municipal solid waste gasification, electro-farming (biomass gasifier and PEM fuel cell), wind/hydrogen hybrid system for remote sites, home electrolysis and alternate infrastructure options, renewable-based electrolysis to fuel PEM fuel cell vehicle fleet, and geothermal energy used to produce hydrogen. These systems are compared to conventional and benchmark technologies. Interim results and findings are presented. Independent analyses emphasize quality, integrity, objectivity, a long-term perspective, corporate memory, and the merging of technical, economic, operational, and programmatic expertise.

  20. Energy-Systems Economic Analysis

    Science.gov (United States)

    Doane, J.; Slonski, M. L.; Borden, C. S.

    1982-01-01

    Energy Systems Economic Analysis (ESEA) program is flexible analytical tool for rank ordering of alternative energy systems. Basic ESEA approach derives an estimate of those costs incurred as result of purchasing, installing and operating an energy system. These costs, suitably aggregated into yearly costs over lifetime of system, are divided by expected yearly energy output to determine busbar energy costs. ESEA, developed in 1979, is written in FORTRAN IV for batch execution.

  1. Revision of the Wayne State University Medical Library subject catalog using the 1966 Medical Subject Heading system.

    Science.gov (United States)

    Pings, V M; Ferrario, J A

    1967-01-01

    Wayne State University Medical Library (WSUML) revised its monograph subject catalog in 1961 utilizing the 1960 edition of MeSH as an authority list. With the introduction of MEDLARS in 1963 by NLM, all topical subheadings were omitted from MeSH. Inasmuch as this omission could not accommodate the needs of WSUML, the 1960 edition of MeSH was retained as a guideline. In January 1966, when MeSH resumed the incorporation of topical subheadings, WSUML was faced with a decision whether to continue the current policy or to adopt the form as presented in the latest edition of MeSH. This report describes the methodology employed in adopting a new policy, the findings which resulted from the change, and an evaluation of this reorganization.

  2. Sleep quality and obesity in young subjects: a meta-analysis.

    Science.gov (United States)

    Fatima, Y; Doi, S A R; Mamun, A A

    2016-11-01

    To assess the effect of poor sleep quality on Overweight/Obesity (Ow/Ob) in young subjects, and explore if this association is independent of sleep duration. Pubmed, EMBASE, and MEDLINE databases were searched for papers on sleep quality and overweight/obesity, focusing on children, adolescents, and young adults. Studies based on subjects with medical/psychological problems or published in languages other than English were excluded. Quality effects model was used to pool studies for meta-analysis. Findings from the systematic review suggest a link between poor sleep quality and Ow/Ob in young subjects. Pooled estimate (from 26,553 subjects) suggest a role of inadequate sleep (including both short duration and poor quality) in Ow/Ob (OR: 1.27 95% CI: 1.05-1.53). Sub-group-analyses suggest considerably higher odds of Ow/Ob (OR = 1.46, 95% CI: 1.24-1.72) in young subjects with poor sleep quality (independent of duration). Poor sleep quality seems to be associated with Ow/Ob, and some studies indicate this association to be independent of duration. Therefore, considering only sleep duration might not help in disentangling sleep-obesity association. However, this review is mostly composed of cross-sectional studies. Therefore, a causal link or the stability of the sleep quality and Ow/Ob association could not be established. © 2016 World Obesity.

  3. Experimental and numerical analysis of aramid fiber laminates with DCPD resin matrix subjected to impact tests

    Directory of Open Access Journals (Sweden)

    Bocian Miroslaw

    2017-01-01

    Full Text Available Research for innovative composite material solutions for impact absorbers is focused on the analysis of their ability to absorb impact energy. For this purpose, aramid fiber laminate with DCPD resin matrix was prepared. Laminate samples were tested on the drop test and were subjected to ballistic loads. The laminate structure was modeled with ABAQUS software with the objective to optimize and estimate the ability to absorb impact energy in the range of high speeds (350m/s.

  4. Experimental and numerical analysis of aramid fiber laminates with DCPD resin matrix subjected to impact tests

    OpenAIRE

    Bocian Miroslaw; Pach Joanna; Jamroziak Krzysztof; Kosobudzki Mariusz; Polak Slawomir; Pyka Dariusz; Kurzawa Adam; Kurowski Janusz

    2017-01-01

    Research for innovative composite material solutions for impact absorbers is focused on the analysis of their ability to absorb impact energy. For this purpose, aramid fiber laminate with DCPD resin matrix was prepared. Laminate samples were tested on the drop test and were subjected to ballistic loads. The laminate structure was modeled with ABAQUS software with the objective to optimize and estimate the ability to absorb impact energy in the range of high speeds (350m/s).

  5. Multi-modal analysis of genetically-related subjects using SIFT descriptors in brain MRI

    OpenAIRE

    Kumar, Kuldeep; Chauvin, Laurent; Toews, Mathew; Colliot, Olivier; Desrosiers, Christian

    2017-01-01

    International audience; So far, fingerprinting studies have focused on identifying features from single-modality MRI data, which capture individual characteristics in terms of brain structure, function, or white matter microstruc-ture. However, due to the lack of a framework for comparing across multiple modalities, studies based on multi-modal data remain elusive. This paper presents a multi-modal analysis of genetically-related subjects to compare and contrast the information provided by va...

  6. Proceedings of the 4th Workshop on Computational Approaches to Subjectivity, Sentiment and Social Media Analysis

    OpenAIRE

    BALAHUR DOBRESCU ALEXANDRA; VAN DER GOOT Erik

    2013-01-01

    Research in automatic Subjectivity and Sentiment Analysis, as subtasks in Affective Computing within the Artificial Intelligence field of Natural Language Processing (NLP), has flourished in the past years. The growth in interest in these tasks was motivated by the birth and rapid expansion of the Social Web that made it possible for people all over the world to share, comment or consult content on any given topic. In this context, opinions, sentiments and emotions expressed in Social Medi...

  7. Supporting Space Systems Design via Systems Dependency Analysis Methodology

    Science.gov (United States)

    Guariniello, Cesare

    The increasing size and complexity of space systems and space missions pose severe challenges to space systems engineers. When complex systems and Systems-of-Systems are involved, the behavior of the whole entity is not only due to that of the individual systems involved but also to the interactions and dependencies between the systems. Dependencies can be varied and complex, and designers usually do not perform analysis of the impact of dependencies at the level of complex systems, or this analysis involves excessive computational cost, or occurs at a later stage of the design process, after designers have already set detailed requirements, following a bottom-up approach. While classical systems engineering attempts to integrate the perspectives involved across the variety of engineering disciplines and the objectives of multiple stakeholders, there is still a need for more effective tools and methods capable to identify, analyze and quantify properties of the complex system as a whole and to model explicitly the effect of some of the features that characterize complex systems. This research describes the development and usage of Systems Operational Dependency Analysis and Systems Developmental Dependency Analysis, two methods based on parametric models of the behavior of complex systems, one in the operational domain and one in the developmental domain. The parameters of the developed models have intuitive meaning, are usable with subjective and quantitative data alike, and give direct insight into the causes of observed, and possibly emergent, behavior. The approach proposed in this dissertation combines models of one-to-one dependencies among systems and between systems and capabilities, to analyze and evaluate the impact of failures or delays on the outcome of the whole complex system. The analysis accounts for cascading effects, partial operational failures, multiple failures or delays, and partial developmental dependencies. The user of these methods can

  8. Uric acid levels in subjects with bipolar disorder: A comparative meta-analysis.

    Science.gov (United States)

    Bartoli, Francesco; Crocamo, Cristina; Mazza, Mario Gennaro; Clerici, Massimo; Carrà, Giuseppe

    2016-10-01

    Previous research has hypothesised increased uric acid levels, possibly because of an amplified purinergic metabolism and a reduced adenosine activity, in subjects with bipolar disorder. This systematic review and meta-analysis aimed at estimating if individuals with bipolar disorder had uric acid levels higher than both healthy controls and subjects with major depression (trait marker hypothesis). It also tested if uric acid levels could differ in different phases of bipolar disorder (state marker hypothesis). Meta-analyses were carried out generating pooled standardized mean differences (SMDs), using random-effects models. Heterogeneity between studies was estimated using the I(2) index. Relevant sensitivity and meta-regression analyses were conducted. We searched main Electronic Databases, identifying twelve studies that met our inclusion criteria. Meta-analyses showed increased uric acid levels in individuals with bipolar disorder as compared with both healthy controls (SMD = 0.65, p uric acid levels were higher in manic/mixed phases as compared with depressive ones (SMD = 0.34; p = 0.04, I(2) = 58.8%), a sensitivity analysis did not confirm the association. In sum, our meta-analysis shows that subjects with bipolar disorder have uric acid levels higher than healthy controls. The potential role of factors that might clarify the nature of this association deserves additional research. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Favored subjects and psychosocial needs in music therapy in terminally ill cancer patients: a content analysis.

    Science.gov (United States)

    Preissler, Pia; Kordovan, Sarah; Ullrich, Anneke; Bokemeyer, Carsten; Oechsle, Karin

    2016-05-12

    Research has shown positive effects of music therapy on the physical and mental well-being of terminally ill patients. This study aimed to identify favored subjects and psychosocial needs of terminally ill cancer patients during music therapy and associated factors. Forty-one Patients receiving specialized inpatient palliative care prospectively performed a music therapy intervention consisting of at least two sessions (total number of sessions: 166; per patient average: 4, range, 2-10). Applied music therapy methods and content were not pre-determined. Therapeutic subjects and psychosocial needs addressed in music therapy sessions were identified from prospective semi-structured "field notes" using qualitative content analysis. Patient- and treatment-related characteristics as well as factors related to music and music therapy were assessed by questionnaire or retrieved from medical records. Seven main categories of subjects were identified: "condition, treatment, further care", "coping with palliative situation", "emotions and feelings", "music and music therapy", "biography", "social environment", and "death, dying, and spiritual topics". Patients addressed an average of 4.7 different subjects (range, 1-7). Some subjects were associated with gender (p = .022) and prior impact of music in patients' life (p = .012). The number of subjects per session was lower when receptive music therapy methods were used (p = .040). Psychosocial needs were categorized into nine main dimensions: "relaxing and finding comfort", "communication and dialogue", "coping and activation of internal resources", "activity and vitality", "finding expression", "sense of self and reflection", "finding emotional response", "defocusing and diversion", and "structure and hold". Patients expressed an average of 4.9 psychosocial needs (range, 1-8). Needs were associated with age, parallel art therapy (p = .010), role of music in patient's life (p = .021), and the applied music

  10. Space radiator simulation system analysis

    Science.gov (United States)

    Black, W. Z.; Wulff, W.

    1972-01-01

    A transient heat transfer analysis was carried out on a space radiator heat rejection system exposed to an arbitrarily prescribed combination of aerodynamic heating, solar, albedo, and planetary radiation. A rigorous analysis was carried out for the radiation panel and tubes lying in one plane and an approximate analysis was used to extend the rigorous analysis to the case of a curved panel. The analysis permits the consideration of both gaseous and liquid coolant fluids, including liquid metals, under prescribed, time dependent inlet conditions. The analysis provided a method for predicting: (1) transient and steady-state, two dimensional temperature profiles, (2) local and total heat rejection rates, (3) coolant flow pressure in the flow channel, and (4) total system weight and protection layer thickness.

  11. Data Analysis of Complex Systems

    Science.gov (United States)

    2011-06-01

    perspectives. A mill study by Cason claims that the system provides great insight into what drives costs, causes of paper machine web breaks, and what...analysis tool). Cason , J. s.l. : Papermakers Conference, 2006. 87. Sutanto. E., Warwick, K. Multivariable cluster analysis for high speed industrial

  12. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation

    Directory of Open Access Journals (Sweden)

    Martinez Fernando J

    2010-03-01

    Full Text Available Abstract Background Numerous studies have demonstrated associations between genetic markers and COPD, but results have been inconsistent. One reason may be heterogeneity in disease definition. Unsupervised learning approaches may assist in understanding disease heterogeneity. Methods We selected 31 phenotypic variables and 12 SNPs from five candidate genes in 308 subjects in the National Emphysema Treatment Trial (NETT Genetics Ancillary Study cohort. We used factor analysis to select a subset of phenotypic variables, and then used cluster analysis to identify subtypes of severe emphysema. We examined the phenotypic and genotypic characteristics of each cluster. Results We identified six factors accounting for 75% of the shared variability among our initial phenotypic variables. We selected four phenotypic variables from these factors for cluster analysis: 1 post-bronchodilator FEV1 percent predicted, 2 percent bronchodilator responsiveness, and quantitative CT measurements of 3 apical emphysema and 4 airway wall thickness. K-means cluster analysis revealed four clusters, though separation between clusters was modest: 1 emphysema predominant, 2 bronchodilator responsive, with higher FEV1; 3 discordant, with a lower FEV1 despite less severe emphysema and lower airway wall thickness, and 4 airway predominant. Of the genotypes examined, membership in cluster 1 (emphysema-predominant was associated with TGFB1 SNP rs1800470. Conclusions Cluster analysis may identify meaningful disease subtypes and/or groups of related phenotypic variables even in a highly selected group of severe emphysema subjects, and may be useful for genetic association studies.

  13. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation.

    Science.gov (United States)

    Cho, Michael H; Washko, George R; Hoffmann, Thomas J; Criner, Gerard J; Hoffman, Eric A; Martinez, Fernando J; Laird, Nan; Reilly, John J; Silverman, Edwin K

    2010-03-16

    Numerous studies have demonstrated associations between genetic markers and COPD, but results have been inconsistent. One reason may be heterogeneity in disease definition. Unsupervised learning approaches may assist in understanding disease heterogeneity. We selected 31 phenotypic variables and 12 SNPs from five candidate genes in 308 subjects in the National Emphysema Treatment Trial (NETT) Genetics Ancillary Study cohort. We used factor analysis to select a subset of phenotypic variables, and then used cluster analysis to identify subtypes of severe emphysema. We examined the phenotypic and genotypic characteristics of each cluster. We identified six factors accounting for 75% of the shared variability among our initial phenotypic variables. We selected four phenotypic variables from these factors for cluster analysis: 1) post-bronchodilator FEV1 percent predicted, 2) percent bronchodilator responsiveness, and quantitative CT measurements of 3) apical emphysema and 4) airway wall thickness. K-means cluster analysis revealed four clusters, though separation between clusters was modest: 1) emphysema predominant, 2) bronchodilator responsive, with higher FEV1; 3) discordant, with a lower FEV1 despite less severe emphysema and lower airway wall thickness, and 4) airway predominant. Of the genotypes examined, membership in cluster 1 (emphysema-predominant) was associated with TGFB1 SNP rs1800470. Cluster analysis may identify meaningful disease subtypes and/or groups of related phenotypic variables even in a highly selected group of severe emphysema subjects, and may be useful for genetic association studies.

  14. Fluid-structure interaction analysis for pressurizer surge line subjected to thermal stratification

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dong Gu [Korea Institute of Nuclear Safety, 19 Guseong-dong, Yuseong-gu, Daejeon 305-338 (Korea, Republic of); Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Jhung, Myung Jo, E-mail: mjj@kins.re.k [Korea Institute of Nuclear Safety, 19 Guseong-dong, Yuseong-gu, Daejeon 305-338 (Korea, Republic of); Chang, Soon Heung [Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701 (Korea, Republic of)

    2011-01-15

    Research highlights: Temperature of surge line due to stratified flow is defined using CFD analysis. Fluid-structure interaction analysis is performed to investigate the response characteristics due to thermal stress. Fatigue usage factors due to thermal stratification are relatively low. Simplifying temperature distribution in surge line is not always conservative. - Abstract: Serious mechanical damages such as cracks and plastic deformations due to excessive thermal stress caused by thermal stratification have been experienced in several nuclear power plants. In particular, the thermal stratification in the pressurizer surge line has been addressed as one of the significant safety and technical issues. In this study, a detailed unsteady computational fluid dynamics (CFD) analysis involving conjugate heat transfer analysis is performed to obtain the transient temperature distributions in the wall of the pressurizer surge line subjected to stratified internal flows either during out-surge or in-surge operation. The thermal loads from CFD calculations are transferred to the structural analysis code which is employed for the thermal stress analysis to investigate the response characteristics, and the fatigue analysis is ultimately performed. In addition, the thermal stress and fatigue analysis results obtained by applying the realistic temperature distributions from CFD calculations are compared with those by assuming the simplified temperature distributions to identify some requirements for a realistic and conservative thermal stress analysis from a safety point of view.

  15. Amputee Subject Testing Protocol, Results, and Analysis of a Powered Transtibial Prosthetic Device

    OpenAIRE

    Sun, Jinming; Fritz, Jessica M.; Del Toro, David R.; Voglewede, Philip A.

    2014-01-01

    A powered ankle-foot prothesis and its control system were previously designed and built. To evaluate this prosthesis, amputee subject testing was performed. The testing results are analyzed and compared between the powered prosthesis, passive prosthesis, and able-bodied gait. Qualitative comparison showed the prosthesis achieved the design objectives. During stance phase, active ankle moment was generated in the powered prosthesis before push-off to help the amputee walk more naturally. Duri...

  16. Robust Synchronization of Fractional-Order Hyperchaotic Systems Subjected to Input Nonlinearity and Unmatched External Perturbations

    Directory of Open Access Journals (Sweden)

    Teh-Lu Liao

    2014-01-01

    Full Text Available This paper investigates the robust synchronization problem for a class of fractional-order hyperchaotic systems subjected to unmatched uncertainties and input nonlinearity. Based on the sliding mode control (SMC technique, this approach only uses a single controller to achieve chaos synchronization, which reduces the cost and complexity for synchronization control implementation. As expected, the error states can be driven to zero or into predictable bounds for matched and unmatched perturbations, respectively, even with input nonlinearity.

  17. Static Analysis for Systems Biology

    DEFF Research Database (Denmark)

    Nielson, Flemming; Nielson, Hanne Riis; Rosa, D. Schuch da

    2004-01-01

    This paper shows how static analysis techniques can help understanding biological systems. Based on a simple example we illustrate the outcome of performing three different analyses extracting information of increasing precision. We conclude by reporting on the potential impact and exploitation o...... of these techniques in systems biology....

  18. Tracking Systems for Virtual Rehabilitation: Objective Performance vs. Subjective Experience. A Practical Scenario

    Directory of Open Access Journals (Sweden)

    Roberto Lloréns

    2015-03-01

    Full Text Available Motion tracking systems are commonly used in virtual reality-based interventions to detect movements in the real world and transfer them to the virtual environment. There are different tracking solutions based on different physical principles, which mainly define their performance parameters. However, special requirements have to be considered for rehabilitation purposes. This paper studies and compares the accuracy and jitter of three tracking solutions (optical, electromagnetic, and skeleton tracking in a practical scenario and analyzes the subjective perceptions of 19 healthy subjects, 22 stroke survivors, and 14 physical therapists. The optical tracking system provided the best accuracy (1.074 ± 0.417 cm while the electromagnetic device provided the most inaccurate results (11.027 ± 2.364 cm. However, this tracking solution provided the best jitter values (0.324 ± 0.093 cm, in contrast to the skeleton tracking, which had the worst results (1.522 ± 0.858 cm. Healthy individuals and professionals preferred the skeleton tracking solution rather than the optical and electromagnetic solution (in that order. Individuals with stroke chose the optical solution over the other options. Our results show that subjective perceptions and preferences are far from being constant among different populations, thus suggesting that these considerations, together with the performance parameters, should be also taken into account when designing a rehabilitation system.

  19. System of Indicators of the Level of Costs of Financing an Economic Subject

    Directory of Open Access Journals (Sweden)

    Laktionova Aleksandra A.

    2013-11-01

    Full Text Available The article offers a system of indicators of the level of costs of financing economic subjects, in the basis of which there is a function of formation of recommendations or identification of directions and priorities in the part of selection of one or another source of financing, its urgency and specific features of attraction of resources, on the basis of information on the level of agent’s costs, information asymmetry costs, financial instability, transaction and market indicators of cost of financial resources. The article pays a special attention to a significant structure forming factor of the ownership structure, which identifies the volume and logic of interconnection of all costs of financing and determining incentives and risks in the system of management of financial activity of an economic subject from the point of view of all participants. It exerts especially big influence upon formation of such implicit costs of financing as agent’s costs and information asymmetry costs. The system of factors of stimulants and de-stimulants of costs of financing includes factors of external environment (macro-economic and market indicators of cost and institutional provision and internal environment (ownership structure, characteristic of investment activity and financing an economic subject, organisation of business and corporate management.

  20. Fiberprint: A subject fingerprint based on sparse code pooling for white matter fiber analysis.

    Science.gov (United States)

    Kumar, Kuldeep; Desrosiers, Christian; Siddiqi, Kaleem; Colliot, Olivier; Toews, Matthew

    2017-09-01

    White matter characterization studies use the information provided by diffusion magnetic resonance imaging (dMRI) to draw cross-population inferences. However, the structure, function, and white matter geometry vary across individuals. Here, we propose a subject fingerprint, called Fiberprint, to quantify the individual uniqueness in white matter geometry using fiber trajectories. We learn a sparse coding representation for fiber trajectories by mapping them to a common space defined by a dictionary. A subject fingerprint is then generated by applying a pooling function for each bundle, thus providing a vector of bundle-wise features describing a particular subject's white matter geometry. These features encode unique properties of fiber trajectories, such as their density along prominent bundles. An analysis of data from 861 Human Connectome Project subjects reveals that a fingerprint based on approximately 3000 fiber trajectories can uniquely identify exemplars from the same individual. We also use fingerprints for twin/sibling identification, our observations consistent with the twin data studies of white matter integrity. Our results demonstrate that the proposed Fiberprint can effectively capture the variability in white matter fiber geometry across individuals, using a compact feature vector (dimension of 50), making this framework particularly attractive for handling large datasets. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Reflexivity and the "Acting Subject": Conceptualizing the Unit of Analysis in Qualitative Health Research.

    Science.gov (United States)

    Shaw, James A

    2016-07-06

    The ways in which social scientists conceptualize the "reflexive" human subject have important consequences for how we go about our research. Whether and how we understand human subjects to be the authors of our own actions helps to structure what we say about health, health care, and the many other topics addressed in qualitative health research. In this article, I critically discuss assumptions of human reflexivity that are built into qualitative social science of health and medicine. I describe three alternative ways of understanding reflexive thought and human action derived from the theoretical works of Pierre Bourdieu, Bruno Latour, and George Lakoff and Mark Johnson, respectively. I then apply these three different ways of thinking about reflexivity and the acting subject to the analysis of an excerpt of participant observation data from a health services research study of transitions from hospital to home, illuminating the different kinds of analyses that arise from each perspective. I conclude with a call for social scientists to commit to the search for better ways of understanding the human subject, resisting the temptation to "settle" on theoretical statements that close down the path to more sophisticated conceptualizations of human thought and action. © The Author(s) 2016.

  2. Subjective Signs Of The State Off-Budget Funds Inappropriate Expenditure Legal Analysis

    Directory of Open Access Journals (Sweden)

    Oleg G. Solovev

    2015-03-01

    Full Text Available In the present article, author discusses controversial issues of the criminal law assessment of subjective symptoms of improper spending of state budget funds, offered legal solutions to separate problems. In particular, analysis of the disposition of Art. 285.2 of the Criminal Code allowed the author to come to the conclusion that in this case we are talking about the even narrower subject, than the official - of the state extra-budgetary fund official. Author notes that the weak point of the technical legal rules, the subjects of the crime cannot be persons, performing managerial functions in the company management, which under the Federal Law of July 24, 2002 No. 111-FL "On the Investment of Funds for Financing funded part of labor pensions in the Russian Federation" pension savings of insured claims transferred to the trust. However, in the case of misuse of these funds, these persons may be held in the presence of all other grounds of criminal responsibility under Art. 201 of the Criminal Code. The subjective aspect of the act is characterized by the acts of guilt in the form of direct intent, when a perpetrator (official understands that spending budget funds illegally and wants them to spend. This purpose of committing crime has no legal significance and do not affect characterization of the offense. Motives of the official (falsely understood interests of the Fund, careerist considerations, greed, and other personal motives, do not affect qualification of his actions, but may be considered in the individualization of responsibility.

  3. Digitized analysis of handwriting and drawing movements in healthy subjects: methods, results and perspectives.

    Science.gov (United States)

    Mergl, R; Tigges, P; Schröter, A; Möller, H J; Hegerl, U

    1999-08-15

    The diagnosis of movement disorders and the distinction between their possible generation by drug-treatment or illness can be done more objectively by using digitized analyses of hand movements. The aim of this study was to define this method, that is to identify its reliability and the influence of several covariables upon measurements, in healthy subjects. Simple writing and drawing tests were administered, using a digitizing tablet, transmitting signals to a computer for processing. The kinematic parameters identified in this way provided objective, reliable and valid measures for the dynamics and the degree of automation of hand movements. Analysis of the data showed that younger subjects write faster and with a higher degree of automation than older subjects. Other moderating variables, such as verbal intelligence and customary motor activity in everyday life (motoric practice) could be identified, whereas personality and gender were found to have little influence. There were no significant differences between left-handers and right-handers in hand movements. The movement parameters had a high test retest stability. The results of this study in healthy subjects indicate that age, verbal intelligence and motor practice should be considered when evaluating the effects of drug-treatment or psychiatric illness upon hand-movement in patients.

  4. The ALICE analysis train system

    CERN Document Server

    Zimmermann, Markus

    2015-01-01

    In the ALICE experiment hundreds of users are analyzing big datasets on a Grid system. High throughput and short turn-around times are achieved by a centralized system called the LEGO trains. This system combines analysis from different users in so-called analysis trains which are then executed within the same Grid jobs thereby reducing the number of times the data needs to be read from the storage systems. The centralized trains improve the performance, the usability for users and the bookkeeping in comparison to single user analysis. The train system builds upon the already existing ALICE tools, i.e. the analysis framework as well as the Grid submission and monitoring infrastructure. The entry point to the train system is a web interface which is used to configure the analysis and the desired datasets as well as to test and submit the train. Several measures have been implemented to reduce the time a train needs to finish and to increase the CPU efficiency.

  5. Assessment of the cardiovascular regulation during robotic assisted locomotion in normal subjects: autoregressive spectral analysis vs empirical mode decomposition.

    Science.gov (United States)

    Magagnin, V; Caiani, E G; Fusini, L; Turiel, M; Licari, V; Bo, I; Cerutti, S; Porta, A

    2008-01-01

    Robotic assisted locomotion systems are recently gaining appreciation as methods to rehabilitate individuals with lost sensory motor function. In the present study we compare autoregressive power spectral analysis and empirical mode decomposition (EMD) applied to the analysis of short-term heart period variability regarding their ability to typify autonomic response during a robotic assisted locomotion session consisting in the following phases: 1) sitting position; 2) standing position; 3) suspension during subject instrumentation; 4) robotic assisted treadmill locomotion with partial body weight support; 5) standing recovery after exercise. Results showed a significant tachycardia during the suspension phase, but no significant changes of spectral indexes. On the contrary, when spectral indexes were derived according to EMD, changes were evidenced during the suspension and walking phases. The EMD method is more powerful than autoregressive spectral analysis in detecting variations of parasympathetic and sympathetic modulations elicited by a robotic-assisted locomotion protocol.

  6. Respiratory system impedance with impulse oscillometry in healthy and COPD subjects: ECLIPSE baseline results.

    Science.gov (United States)

    Crim, Courtney; Celli, Bartolome; Edwards, Lisa D; Wouters, Emiel; Coxson, Harvey O; Tal-Singer, Ruth; Calverley, Peter M A

    2011-07-01

    Current assessment of COPD relies extensively on the use of spirometry, an effort-dependent maneuver. Impulse oscillometry (IOS) is a non-volitional way to measure respiratory system mechanics, but its relationship to structural and functional measurements in large groups of patients with COPD is not clear. We evaluated the ability of IOS to detect and stage COPD severity in the prospective ECLIPSE cohort of COPD patients defined spirometrically, and contrasted with smoking and non-smoking healthy subjects. Additionally, we assessed whether IOS relates to extent of CT-defined emphysema. We measured lung impedance with IOS in healthy non-smokers (n = 233), healthy former smokers (n = 322) or patients with COPD (n = 2054) and related these parameters with spirometry and areas of low attenuation in lung CT. In healthy control subjects, IOS demonstrated good repeatability over 3 months. In the COPD group, respiratory system impedance was worse compared with controls as was frequency dependence of resistance, which related to GOLD stage. However, 29-86% of the COPD subjects had values that fell within the 90% confidence interval of several parameters of the healthy non-smokers. Although mean values for impedance parameters and CT indices worsened as GOLD severity increased, actual correlations between them were poor (r ≤ 0.16). IOS can be reliably used in large cohorts of subjects to assess respiratory system impedance. Cross-sectional data suggest that it may have limited usefulness in evaluating the degree of pathologic disease, whereas its role in assessing disease progression in COPD currently remains undefined. Copyright © 2011. Published by Elsevier Ltd.

  7. Single-subject analysis reveals variation in knee mechanics during step landing.

    Science.gov (United States)

    Scholes, Corey J; McDonald, Michael D; Parker, Anthony W

    2012-08-09

    Evidence concerning the alteration of knee function during landing suffers from a lack of consensus. This uncertainty can be attributed to methodological flaws, particularly in relation to the statistical analysis of variable human movement data. The aim of this study was to compare single-subject and group analyses in detecting changes in knee stiffness and coordination during step landing that occur independent of an experimental intervention. A group of healthy men (N=12) stepped-down from a knee-high platform for 60 consecutive trials, each trial separated by a 1-minute rest. The magnitude and within-participant variability of sagittal stiffness and coordination of the landing knee were evaluated with both group and single-subject analyses. The group analysis detected significant changes in knee coordination. However, the single-subject analyses detected changes in all dependent variables, which included increases in variability with task repetition. Between-individual variation was also present in the timing, size and direction of alterations. The results have important implications for the interpretation of existing information regarding the adaptation of knee mechanics to interventions such as fatigue, footwear or landing height. It is proposed that a participant's natural variation in knee mechanics should be analysed prior to an intervention in future experiments. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Cross Time-Frequency Analysis of Gastrocnemius Electromyographic Signals in Hypertensive and Nonhypertensive Subjects

    Science.gov (United States)

    Mitchell, Patrick; Krotish, Debra; Shin, Yong-June; Hirth, Victor

    2010-12-01

    The effects of hypertension are chronic and continuous; it affects gait, balance, and fall risk. Therefore, it is desirable to assess gait health across hypertensive and nonhypertensive subjects in order to prevent or reduce the risk of falls. Analysis of electromyography (EMG) signals can identify age related changes of neuromuscular activation due to various neuropathies and myopathies, but it is difficult to translate these medical changes to clinical diagnosis. To examine and compare geriatrics patients with these gait-altering diseases, we acquire EMG muscle activation signals, and by use of a timesynchronized mat capable of recording pressure information, we localize the EMG data to the gait cycle, ensuring identical comparison across subjects. Using time-frequency analysis on the EMG signal, in conjunction with several parameters obtained from the time-frequency analyses, we can determine the statistical discrepancy between diseases. We base these parameters on physiological manifestations caused by hypertension, as well as other comorbities that affect the geriatrics community. Using these metrics in a small population, we identify a statistical discrepancy between a control group and subjects with hypertension, neuropathy, diabetes, osteoporosis, arthritis, and several other common diseases which severely affect the geriatrics community.

  9. Subjective acceptability of various regular twelve-tone tuning systems in two-part musical fragments.

    Science.gov (United States)

    Vos, J

    1988-06-01

    Musically trained subjects rated the overall acceptability of the performance of two-part musical fragments. With the help of a computer these fragments were produced with intonations according to various regular 12-tone tuning systems: Pythagorean tuning (tempering T of the fifths equal to 0.0 cent), equal temperament (T = -2.0 cents), Silbermann (T = -3.9 cents), mean-tone (T = -5.4 cents), and Salinas tuning (T = -7.2 cents). In experiment 1, two systems in which T = 2.0 or T = -10.0 cents were also included. In both the lower and the higher parts of the fragments we used complex tones with a spectral-envelope slope of -6 dB/oct. Mean acceptability ratings were about the same for -5.4 less than or equal to T less than or equal to 0.0 cent, whereas for T greater than 0.0 and T less than -5.4 cents the ratings strongly decreased. This effect of tuning system was also found when acceptability was determined by means of the method of paired comparisons. The specific effect of tuning system was not affected by the tempo of the fragments. The perception of beats in the harmonic intervals was manipulated in experiment 2 by varying the spectral content of the tones. The condition in which the interference of the nearly coinciding harmonics was canceled resulted in higher acceptability. The effect of tuning system was the same as in experiment 1. In both experiments overall acceptability could be accurately predicted from a linear combination of the purity ratings of the isolated harmonic fifths and major thirds. It is not precluded, however, that for T greater than 0.0 and T less than -5.4 cents, the subjects based their acceptability ratings partly on the subjective purity of the melodic intervals.

  10. An analysis of university subjects from the field of adapted physical activity in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Ladislav Baloun

    2014-01-01

    Full Text Available BACKGROUND: The inclusion of students with special educational needs is a process, which faces many challenges. An essential condition for the success of inclusion is the competence of physical educators. We suggest that it is necessary to establish courses focused on adapted physical activity as part of the university education for physical education (PE teachers. OBJECTIVES: The aim of this study is to analyze courses focused on adapted physical activity within teacher preparation programs. METHODS: We conducted quantitative and qualitative content analysis of subjects which was focused on adapted physical activity at selected public universities in the Czech Republic. In total, subjects from the six faculties met the conditions. RESULTS: The results show the lack of emphasis for this area in the current PE teacher preparations programs, which is one of basic requirements for success of the inclusion process.

  11. Quantitative analysis of iris changes following mydriasis in subjects with different mechanisms of angle closure.

    Science.gov (United States)

    Zhang, Ye; Li, Si Zhen; Li, Lei; He, Ming Guang; Thomas, Ravi; Wang, Ning Li

    2015-01-08

    We estimate and compare change in iris cross-sectional area (IA) after physiologic and pharmacologic mydriasis in subjects with different dominant mechanisms for primary angle closure. Anterior segment optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were obtained on primary angle closure suspects (PACS), primary angle closure (PAC), and primary angle closure glaucoma (PACG) examined during the 5-year follow-up of the Handan Eye Study. Subjects were categorized into three subgroups according to their dominant angle closure (AC) mechanisms as determined by AS-OCT: pupillary block (PB), plateau iris configuration (PIC), and thick peripheral iris roll (TPIR). The IA and other biometric parameters measured using the Zhongshan Angle Assessment Program in the right eyes of all subjects were analyzed. A total of 364 right eyes of subjects with PACS (333), and PAC/PACG (31) was included in the analysis. Significant differences in the change of IAs (P = 0.030), IA loss per mm pupil diameter (PD) increase (P = 0.001) in light versus pharmacologic dilation, and IA loss per mm PD increase (P = 0.011) from dark versus pharmacologic dilation were observed among the three groups. The smallest decrease occurred in the PB group. There are significant differences in IA and IA loss per mm of pupil change following physiologic or pharmacologic mydriasis in Chinese subjects with dissimilar dominant mechanisms for AC. Dynamic iris change may have a more important role in angle closure where PB is the dominant mechanism. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.

  12. Principal components analysis of an evaluation of the hemiplegic subject based on the Bobath approach.

    Science.gov (United States)

    Corriveau, H; Arsenault, A B; Dutil, E; Lepage, Y

    1992-01-01

    An evaluation based on the Bobath approach to treatment has previously been developed and partially validated. The purpose of the present study was to verify the content validity of this evaluation with the use of a statistical approach known as principal components analysis. Thirty-eight hemiplegic subjects participated in the study. Analysis of the scores on each of six parameters (sensorium, active movements, muscle tone, reflex activity, postural reactions, and pain) was evaluated on three occasions across a 2-month period. Each time this produced three factors that contained 70% of the variation in the data set. The first component mainly reflected variations in mobility, the second mainly variations in muscle tone, and the third mainly variations in sensorium and pain. The results of such exploratory analysis highlight the fact that some of the parameters are not only important but also interrelated. These results seem to partially support the conceptual framework substantiating the Bobath approach to treatment.

  13. Coupling system dynamics and contact behaviour: Modelling bearings subjected to environmental induced vibrations and ‘false brinelling’ degradation

    Science.gov (United States)

    Massi, Francesco; Rocchi, J.; Culla, A.; Berthier, Y.

    2010-05-01

    During the last decades the increase in power of mechanical systems and the demand for increasing service life leads mechanical components of a system to work in extreme conditions. Moreover, actual mechanical systems include surfaces in sliding contact that are subjected to wear if exposed to high vibration. In fact, the vibration of components in contact results in large oscillations of the local contact stresses, due to the local deformation of the components at the contact interfaces. To approach correctly tribological problems, the coupling between the scale of the mechanism (system dynamics) and the scale of the contact needs to be accounted for. This paper presents an analysis concerning the influence of the vibrations induced by aircraft engines on the contact stresses of rolling bearings of the bleed system valves. To study the wear, resulting from false brinelling at the contact surfaces between balls and races of the bearings, it is then necessary to determine the forces due to the system vibrations and acting at the bearing connections with the structure. In order to perform a numerical transient analysis of the system dynamics a nonlinear simplified model of the valve (mechanism scale) is developed. The model is validated by comparing the numerical results with experimental tests. The time behaviour of the global forces on the bearings, and the respective displacements between the contact surfaces, are then used as inputs for a finite element model of the bearings (contact scale). The model is used to calculate and analyze the behaviour in time of the local contact constraints between race and balls. This analysis, developed in the framework of a European project, is an example of the proposed general approach to contact problems, by coupling the analysis of the mechanism and contact scales.

  14. Types of adaptation of the system of enterprise economic security to the impact of subjects of tax regulation

    Directory of Open Access Journals (Sweden)

    Pohorelov Yurii S.

    2014-01-01

    Full Text Available The article offers the authors’ approach to identification of types of adaptation of the system of enterprise economic security to negative influence of subjects of tax regulation. It determines composition of these subjects and, separately, regulation subjects that form fundamental grounds of the tax sphere and subjects of effective influence, which directly interact with entrepreneurial structures and realise tax regulation of their activity in practice. As regards direct adaptation of the system of enterprise economic security, the article offers to mark out its individual types with respect to the set goal, essence of changes in the system of economic security, degree of its manageability and nature of accumulated changes. Moreover, the article offers a list of catalysts and inhibitors of adaptation of the system of enterprise economic security to impact of subjects of tax regulation. It also marks out adaptation parameters of the system of enterprise economic security to the impact of subjects of tax regulation and provides their gradations.

  15. Distribution system modeling and analysis

    CERN Document Server

    Kersting, William H

    2002-01-01

    For decades, distribution engineers did not have the sophisticated tools developed for analyzing transmission systems-often they had only their instincts. Things have changed, and we now have computer programs that allow engineers to simulate, analyze, and optimize distribution systems. Powerful as these programs are, however, without a real understanding of the operating characteristics of a distribution system, engineers using the programs can easily make serious errors in their designs and operating procedures.Distribution System Modeling and Analysis helps prevent those errors. It gives re

  16. Quantitative electroencephalogram (QEEG Spectrum Analysis of Patients with Schizoaffective Disorder Compared to Normal Subjects.

    Directory of Open Access Journals (Sweden)

    Mahdi Moeini

    2014-12-01

    Full Text Available The aim of this study was to achieve a better understanding of schizoaffective disorder. Therefore, we obtained electroencephalogram (EEG signals from patients with schizoaffective disorder and analyzed them in comparison to normal subjects.Forty patients with schizoaffective disorder and 40 normal subjects were selected randomly and their electroencephalogram signals were recorded based on 10-20 international system by 23 electrodes in open- and closed-eyes while they were sitting on a chair comfortably. After preprocessing for noise removal and artifact reduction, we took 60- second segments from each recorded signals. Then, the absolute and relative powers of these segments were evaluated in all channels and in 4 frequency bands (i.e., delta, theta, alpha and beta waves. Finally, Data were analyzed by independent t-test using SPSS software.A significant decrease in relative power in the alpha band, a significant decrease in power spectra in the alpha band and a significant increase in power spectra in the beta band were found in patients compared to normal subjects (P < 0.05. The predominant wave in the centro-parietal region was the beta wave in patients, but it was the alpha band in normal subjects (P = 0.048. Also, the predominant wave of the occipital region in patients was the delta wave, while it was the alpha wave in normal subjects (P = 0.038.Considering the findings, particularly based on the significant decrease of the alpha waves in schizoaffective patients, it can be concluded that schizoaffective disorder can be seen in schizophrenia spectrum.

  17. Dynamic interactions of an integrated vehicle-electromagnetic energy harvester-tire system subject to uneven road excitations

    Science.gov (United States)

    Xing, Jing Tang; Sun, Zhe; Zhou, Sulian; Tan, Mingyi

    2017-04-01

    An investigation is undertaken of an integrated mechanical-electromagnetic coupling system consisting of a rigid vehicle with heave, roll, and pitch motions, four electromagnetic energy harvesters and four tires subject to uneven road excitations in order to improve the passengers' riding comfort and harvest the lost engine energy due to uneven roads. Following the derived mathematical formulations and the proposed solution approaches, the numerical simulations of this interaction system subject to a continuous sinusoidal road excitation and a single ramp impact are completed. The simulation results are presented as the dynamic response curves in the forms of the frequency spectrum and the time history, which reveals the complex interaction characteristics of the system for vibration reductions and energy harvesting performance. It has addressed the coupling effects on the dynamic characteristics of the integrated system caused by: (1) the natural modes and frequencies of the vehicle; (2) the vehicle rolling and pitching motions; (3) different road excitations on four wheels; (4) the time delay of a road ramp to impact both the front and rear wheels, etc., which cannot be tackled by an often used quarter vehicle model. The guidelines for engineering applications are given. The developed coupling model and the revealed concept provide a means with analysis idea to investigate the details of four energy harvester motions for electromagnetic suspension designs in order to replace the current passive vehicle isolators and to harvest the lost engine energy. Potential further research directions are suggested for readers to consider in the future.

  18. Performance of Purunã beef calves subjected to different weaning systems

    Directory of Open Access Journals (Sweden)

    Fernando Kuss

    2014-09-01

    Full Text Available The study was developed at Fazenda Modelo an Experimental Station belonged to the Instituto Agronômico do Paraná - IAPAR, in the city of Ponta Grossa, PR, from June to November 2011. The objective was to evaluate the performance of calves subjected to different weaning systems. 161 calves crossbred Purunã were divided into three groups: calves subjected to early weaning (DP, weaned at an average of 75 days old; calves subjected to controlled nursing system (AC with 75 days of age, exposed to suck only once a day during the duration of the breeding season (85 days and; the control group, calves submitted to the system of conventional weaning (DC, were kept together with cow, without interfering in breastfeeding until the end of the breeding season (85 days. Calves fed the DP had lower mean (P<0.05 average daily gain (0.56 kg during the experimental group compared to the AC and DC (0.95 kg and 0.88 kg, respectively which did not differ (P<0.05. Thus, the DP had calves at the end of the breeding season, 32.36 kg and 26.48 kg unless the AC group (167.44 kg and DC (161.56 kg, respectively. The system controlled breastfeeding does not provid damage on the performance of calves at 150 days of age. Already early weaning at 75 days cause decrease of 19.6% in weight of calves at 150 days of age compared to suckler calves.

  19. Double coupling: modeling subjectivity and asymmetric organization in social-ecological systems

    Directory of Open Access Journals (Sweden)

    David Manuel-Navarrete

    2015-09-01

    Full Text Available Social-ecological organization is a multidimensional phenomenon that combines material and symbolic processes. However, the coupling between social and ecological subsystem is often conceptualized as purely material, thus reducing the symbolic dimension to its behavioral and actionable expressions. In this paper I conceptualize social-ecological systems as doubly coupled. On the one hand, material expressions of socio-cultural processes affect and are affected by ecological dynamics. On the other hand, coupled social-ecological material dynamics are concurrently coupled with subjective dynamics via coding, decoding, personal experience, and human agency. This second coupling operates across two organizationally heterogeneous dimensions: material and symbolic. Although resilience thinking builds on the recognition of organizational asymmetry between living and nonliving systems, it has overlooked the equivalent asymmetry between ecological and socio-cultural subsystems. Three guiding concepts are proposed to formalize double coupling. The first one, social-ecological asymmetry, expands on past seminal work on ecological self-organization to incorporate reflexivity and subjectivity in social-ecological modeling. Organizational asymmetry is based in the distinction between social rules, which are symbolically produced and changed through human agents' reflexivity and purpose, and biophysical rules, which are determined by functional relations between ecological components. The second guiding concept, conscious power, brings to the fore human agents' distinctive capacity to produce our own subjective identity and the consequences of this capacity for social-ecological organization. The third concept, congruence between subjective and objective dynamics, redefines sustainability as contingent on congruent relations between material and symbolic processes. Social-ecological theories and analyses based on these three guiding concepts would support the

  20. The effect of sleep deprivation on pain perception in healthy subjects: a meta-analysis.

    Science.gov (United States)

    Schrimpf, Marlene; Liegl, Gregor; Boeckle, Markus; Leitner, Anton; Geisler, Peter; Pieh, Christoph

    2015-11-01

    There is strong evidence indicating an interaction between sleep and pain. However, the size of this effect, as well as the clinical relevance, is unclear. Therefore, this meta-analysis was conducted to quantify the effect of sleep deprivation on pain perception. A systematic literature search was conducted using the electronic databases PubMed, Cochrane, Psyndex, Psycinfo, and Scopus. By conducting a random-effect model, the pooled standardized mean differences (SMDs) of sleep deprivation on pain perception was calculated. Studies that investigated any kind of sleep deprivation in conjunction with a pain measurement were included. In cases of several pain measurements within a study, the average effect size of all measures was calculated. Five eligible studies (N = 190) for the between-group analysis and ten studies (N = 266) for the within-group analysis were identified. Sleep deprivation showed a medium effect in the between-group analysis (SMD = 0.62; CI95: 0.12, 1.12; z = 2.43; p = 0.015) and a large effect in the within-group analysis (SMD = 1.49; CI95: 0.82, 2.17; z = 4.35; p sleep deprivation on pain perception. As this meta-analysis is based on experimental studies in healthy subjects, the clinical relevance should be clarified. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Fuzzy Stabilization for Nonlinear Discrete Ship Steering Stochastic Systems Subject to State Variance and Passivity Constraints

    Directory of Open Access Journals (Sweden)

    Wen-Jer Chang

    2014-01-01

    Full Text Available For nonlinear discrete-time stochastic systems, a fuzzy controller design methodology is developed in this paper subject to state variance constraint and passivity constraint. According to fuzzy model based control technique, the nonlinear discrete-time stochastic systems considered in this paper are represented by the discrete-time Takagi-Sugeno fuzzy models with multiplicative noise. Employing Lyapunov stability theory, upper bound covariance control theory, and passivity theory, some sufficient conditions are derived to find parallel distributed compensation based fuzzy controllers. In order to solve these sufficient conditions, an iterative linear matrix inequality algorithm is applied based on the linear matrix inequality technique. Finally, the fuzzy stabilization problem for nonlinear discrete ship steering stochastic systems is investigated in the numerical example to illustrate the feasibility and validity of proposed fuzzy controller design method.

  2. On the thermal stability of a radiating plasma subject to nonlocal thermal conduction. I - Linear analysis

    Science.gov (United States)

    Chun, E.; Rosner, R.

    1993-01-01

    We study the linear stability of an optically thin uniform radiating plasma subject to nonlocal heat transport. We derive the dispersion relation appropriate to this problem, and the marginal wavenumbers for instability. Our analysis indicates that nonlocal heat transport acts to reduce the stabilizing influence of thermal conduction, and that there are critical values for the electron mean free path such that the plasma is always unstable. Our results may be applied to a number of astrophysical plasmas, one such example being the halos of clusters of galaxies.

  3. A finite element large deflection random response analysis of beams and plates subjected to acoustic loading

    Science.gov (United States)

    Mei, Chuh; Chiang, C. K.

    1987-01-01

    A finite element formulation is presented for the analysis of beams and rectangular plates undergoing large deflections subjected to Gaussian white noise excitations. Single-mode response is assumed in the present formulation. Root-mean-square (RMS) maximum deflections for simply supported and clamped beams and plates at various sound spectrum levels are obtained and compared with solutions using the Fokker-Planck-Kolmogorov equation and the equivalent linearization methods. RMS maximum stains and equivalent linear frequencies are compared with the equivalent linearization results for assessment of the accuracy of the finite element method.

  4. Nonparametric and Semiparametric Analysis of Current Status Data Subject to Outcome Misclassification.

    Science.gov (United States)

    Sal Y Rosas, Victor G; Hughes, James P

    2010-04-21

    In this article, we present nonparametric and semiparametric methods to analyze current status data subject to outcome misclassification. Our methods use nonparametric maximum likelihood estimation (NPMLE) to estimate the distribution function of the failure time when sensitivity and specificity are known and may vary among subgroups. A nonparametric test is proposed for the two sample hypothesis testing. In regression analysis, we apply the Cox proportional hazard model and likelihood ratio based confidence intervals for the regression coefficients are proposed. Our methods are motivated and demonstrated by data collected from an infectious disease study in Seattle, WA.

  5. Distribution system modeling and analysis

    CERN Document Server

    Kersting, William H

    2001-01-01

    For decades, distribution engineers did not have the sophisticated tools developed for analyzing transmission systems-often they had only their instincts. Things have changed, and we now have computer programs that allow engineers to simulate, analyze, and optimize distribution systems. Powerful as these programs are, however, without a real understanding of the operating characteristics of a distribution system, engineers using the programs can easily make serious errors in their designs and operating procedures. Distribution System Modeling and Analysis helps prevent those errors. It gives readers a basic understanding of the modeling and operating characteristics of the major components of a distribution system. One by one, the author develops and analyzes each component as a stand-alone element, then puts them all together to analyze a distribution system comprising the various shunt and series devices for power-flow and short-circuit studies. He includes the derivation of all models and includes many num...

  6. Requirements analysis and system design

    CERN Document Server

    Maciaszek, Leszek A

    2007-01-01

    An examination of the methods and techniques used in the analysis and design phases of Information System development. Emphasis is placed upon the application of object technology in enterprise information systems (EIS) with UML being used throughout. Through its excellent balance of practical explanation and theoretical insight the book manages to avoid unnecessary, complicating details without sacrificing rigor. Examples of real-world scenarios are used throughout, giving the reader an understanding of what really goes on within the field of Software Engineering.

  7. Experimental gingivitis induces systemic inflammatory markers in young healthy individuals: a single-subject interventional study.

    Science.gov (United States)

    Eberhard, Jörg; Grote, Karsten; Luchtefeld, Maren; Heuer, Wieland; Schuett, Harald; Divchev, Dimitar; Scherer, Ralph; Schmitz-Streit, Ruth; Langfeldt, Daniela; Stumpp, Nico; Staufenbiel, Ingmar; Schieffer, Bernhard; Stiesch, Meike

    2013-01-01

    We here investigated whether experimental gingivitis enhances systemic markers of inflammation which are also known as surrogate markers of atherosclerotic plaque development. Gingivitis is a low-level oral infection induced by bacterial deposits with a high prevalence within Western populations. A potential link between the more severe oral disease periodontitis and cardiovascular disease has already been shown. 37 non-smoking young volunteers with no inflammatory disease or any cardiovascular risk factors participated in this single-subject interventional study with an intra-individual control. Intentionally experimental oral inflammation was induced by the interruption of oral hygiene for 21 days, followed by a 21-days resolving phase after reinitiation of oral hygiene. Primary outcome measures at baseline, day 21 and 42 were concentrations of hsCRP, IL-6, and MCP-1, as well as adhesion capacity and oxLDL uptake of isolated blood monocytes. The partial cessation of oral hygiene procedures was followed by the significant increase of gingival bleeding (34.0%, Pgingivitis. Bacterial-induced gingival low-level inflammation induced a systemic increase in inflammatory markers. Dental hygiene almost completely reversed this experimental inflammatory process, suggesting that appropriate dental prophylaxis may also limit systemic markers of inflammation in subjects with natural gingivitis. International Clinical Trials Register Platform of the World Health Organization, registry number: DRKS00003366, URL: http://apps.who.int/trialsearch/Default.aspx.

  8. Automated Loads Analysis System (ATLAS)

    Science.gov (United States)

    Gardner, Stephen; Frere, Scot; O’Reilly, Patrick

    2013-01-01

    ATLAS is a generalized solution that can be used for launch vehicles. ATLAS is used to produce modal transient analysis and quasi-static analysis results (i.e., accelerations, displacements, and forces) for the payload math models on a specific Shuttle Transport System (STS) flight using the shuttle math model and associated forcing functions. This innovation solves the problem of coupling of payload math models into a shuttle math model. It performs a transient loads analysis simulating liftoff, landing, and all flight events between liftoff and landing. ATLAS utilizes efficient and numerically stable algorithms available in MSC/NASTRAN.

  9. Amputee Subject Testing Protocol, Results, and Analysis of a Powered Transtibial Prosthetic Device.

    Science.gov (United States)

    Sun, Jinming; Fritz, Jessica M; Del Toro, David R; Voglewede, Philip A

    2014-12-01

    A powered ankle-foot prothesis and its control system were previously designed and built. To evaluate this prosthesis, amputee subject testing was performed. The testing results are analyzed and compared between the powered prosthesis, passive prosthesis, and able-bodied gait. Qualitative comparison showed the prosthesis achieved the design objectives. During stance phase, active ankle moment was generated in the powered prosthesis before push-off to help the amputee walk more naturally. During swing phase, the powered prosthesis was able to move to natural position to achieve foot clearance. However, the prosthesis is slightly under powered compared with the able-bodied ankle.

  10. Hemispheric lateralization in an analysis of speech sounds. Left hemisphere dominance replicated in Japanese subjects.

    Science.gov (United States)

    Koyama, S; Gunji, A; Yabe, H; Oiwa, S; Akahane-Yamada, R; Kakigi, R; Näätänen, R

    2000-09-01

    Evoked magnetic responses to speech sounds [R. Näätänen, A. Lehtokoski, M. Lennes, M. Cheour, M. Huotilainen, A. Iivonen, M. Vainio, P. Alku, R.J. Ilmoniemi, A. Luuk, J. Allik, J. Sinkkonen and K. Alho, Language-specific phoneme representations revealed by electric and magnetic brain responses. Nature, 385 (1997) 432-434.] were recorded from 13 Japanese subjects (right-handed). Infrequently presented vowels ([o]) among repetitive vowels ([e]) elicited the magnetic counterpart of mismatch negativity, MMNm (Bilateral, nine subjects; Left hemisphere alone, three subjects; Right hemisphere alone, one subject). The estimated source of the MMNm was stronger in the left than in the right auditory cortex. The sources were located posteriorly in the left than in the right auditory cortex. These findings are consistent with the results obtained in Finnish [R. Näätänen, A. Lehtokoski, M. Lennes, M. Cheour, M. Huotilainen, A. Iivonen, M.Vainio, P.Alku, R.J. Ilmoniemi, A. Luuk, J. Allik, J. Sinkkonen and K. Alho, Language-specific phoneme representations revealed by electric and magnetic brain responses. Nature, 385 (1997) 432-434.][T. Rinne, K. Alho, P. Alku, M. Holi, J. Sinkkonen, J. Virtanen, O. Bertrand and R. Näätänen, Analysis of speech sounds is left-hemisphere predominant at 100-150 ms after sound onset. Neuroreport, 10 (1999) 1113-1117.] and English [K. Alho, J.F. Connolly, M. Cheour, A. Lehtokoski, M. Huotilainen, J. Virtanen, R. Aulanko and R.J. Ilmoniemi, Hemispheric lateralization in preattentive processing of speech sounds. Neurosci. Lett., 258 (1998) 9-12.] subjects. Instead of the P1m observed in Finnish [M. Tervaniemi, A. Kujala, K. Alho, J. Virtanen, R.J. Ilmoniemi and R. Näätänen, Functional specialization of the human auditory cortex in processing phonetic and musical sounds: A magnetoencephalographic (MEG) study. Neuroimage, 9 (1999) 330-336.] and English [K. Alho, J. F. Connolly, M. Cheour, A. Lehtokoski, M. Huotilainen, J. Virtanen, R. Aulanko

  11. Effective brain network analysis with resting-state EEG data: a comparison between heroin abstinent and non-addicted subjects

    Science.gov (United States)

    Hu, Bin; Dong, Qunxi; Hao, Yanrong; Zhao, Qinglin; Shen, Jian; Zheng, Fang

    2017-08-01

    Objective. Neuro-electrophysiological tools have been widely used in heroin addiction studies. Previous studies indicated that chronic heroin abuse would result in abnormal functional organization of the brain, while few heroin addiction studies have applied the effective connectivity tool to analyze the brain functional system (BFS) alterations induced by heroin abuse. The present study aims to identify the abnormality of resting-state heroin abstinent BFS using source decomposition and effective connectivity tools. Approach. The resting-state electroencephalograph (EEG) signals were acquired from 15 male heroin abstinent (HA) subjects and 14 male non-addicted (NA) controls. Multivariate autoregressive models combined independent component analysis (MVARICA) was applied for blind source decomposition. Generalized partial directed coherence (GPDC) was applied for effective brain connectivity analysis. Effective brain networks of both HA and NA groups were constructed. The two groups of effective cortical networks were compared by the bootstrap method. Abnormal causal interactions between decomposed source regions were estimated in the 1-45 Hz frequency domain. Main results. This work suggested: (a) there were clear effective network alterations in heroin abstinent subject groups; (b) the parietal region was a dominant hub of the abnormally weaker causal pathways, and the left occipital region was a dominant hub of the abnormally stronger causal pathways. Significance. These findings provide direct evidence that chronic heroin abuse induces brain functional abnormalities. The potential value of combining effective connectivity analysis and brain source decomposition methods in exploring brain alterations of heroin addicts is also implied.

  12. Quantitative electroencephalogram (QEEG) Spectrum Analysis of Patients with Schizoaffective Disorder Compared to Normal Subjects.

    Science.gov (United States)

    Moeini, Mahdi; Khaleghi, Ali; Amiri, Nasrin; Niknam, Zahra

    2014-10-01

    The aim of this study was to achieve a better understanding of schizoaffective disorder. Therefore, we obtained electroencephalogram (EEG) signals from patients with schizoaffective disorder and analyzed them in comparison to normal subjects. Forty patients with schizoaffective disorder and 40 normal subjects were selected randomly and their electroencephalogram signals were recorded based on 10-20 international system by 23 electrodes in open- and closed-eyes while they were sitting on a chair comfortably. After preprocessing for noise removal and artifact reduction, we took 60- second segments from each recorded signals. Then, the absolute and relative powers of these segments were evaluated in all channels and in 4 frequency bands (i.e., delta, theta, alpha and beta waves). Finally, Data were analyzed by independent t-test using SPSS software. A significant decrease in relative power in the alpha band, a significant decrease in power spectra in the alpha band and a significant increase in power spectra in the beta band were found in patients compared to normal subjects (P schizoaffective patients, it can be concluded that schizoaffective disorder can be seen in schizophrenia spectrum.

  13. A Nonimmunosuppressant Approach on Asia Psoriasis Subjects: 5-Year Followup and 11-Year Data Analysis

    Directory of Open Access Journals (Sweden)

    Tony Yuqi Tang

    2012-01-01

    Full Text Available Mono- or combine immunosuppressants are commonly used for psoriasis; however the side effect caused by potent systemic immunosuppressants frequently incurred; moreover the inflammation flares up shortly after immunosuppressants are discontinued. An alternative nonimmunosuppressive therapy was introduced to psoriasis subjects. A retrospective observational study consisted of 1583 psoriasis patients who were treated with Herose Psoria capsule 1440 mg three times daily at two clinical centres, one in China, the other in Singapore, from 1 January 2000 to 1 January 2011. Psoriasis lesion evolution was photographed at monthly visit, and efficacy and safety were assessed using psoriasis area severity index PASI score grading, renal and liver function testing, and adverse event reporting and supplemented by information obtained during targeted telephone interviews. The effectiveness of Herose on psoriasis was inversely associated to prior immunosuppressants exposure (r=0.9154, significant improvements occurred in non-immunosuppressants subjects, and complete clearance was achieved in 8 months (87.5%, 14 of 16; the wavelike evolution of psoriatic lesion appeared in prior immunosuppressants subjects.

  14. Sizing Analysis for Aircraft Utilizing Hybrid-Electric Propulsion Systems

    Science.gov (United States)

    2011-03-18

    Lithium-Ion Batteries for Hybrid Electric Vehicles," Mitsubishi Motor Corporation, Japan, Technical Review 15, 2003. [40] Hiroaki et al Yoshida...SIZING ANALYSIS FOR AIRCRAFT UTILIZING HYBRID- ELECTRIC PROPULSION SYSTEMS THESIS Matthew D...of the U.S. Government and is not subject to copyright protection in the United States. AFIT/GAE/ENY/11-M26 SIZING ANALYSIS FOR AIRCRAFT

  15. Systems analysis - independent analysis and verification

    Energy Technology Data Exchange (ETDEWEB)

    DiPietro, J.P.; Skolnik, E.G.; Badin, J.S. [Energetics, Inc., Columbia, MD (United States)

    1996-10-01

    The Hydrogen Program of the U.S. Department of Energy (DOE) funds a portfolio of activities ranging from conceptual research to pilot plant testing. The long-term research projects support DOE`s goal of a sustainable, domestically based energy system, and the development activities are focused on hydrogen-based energy systems that can be commercially viable in the near-term. Energetics develops analytic products that enable the Hydrogen Program Manager to assess the potential for near- and long-term R&D activities to satisfy DOE and energy market criteria. This work is based on a pathway analysis methodology. The authors consider an energy component (e.g., hydrogen production from biomass gasification, hybrid hydrogen internal combustion engine (ICE) vehicle) within a complete energy system. The work involves close interaction with the principal investigators to ensure accurate representation of the component technology. Comparisons are made with the current cost and performance of fossil-based and alternative renewable energy systems, and sensitivity analyses are conducted to determine the effect of changes in cost and performance parameters on the projects` viability.

  16. Stability Criterion of Linear Stochastic Systems Subject to Mixed H2/Passivity Performance

    Directory of Open Access Journals (Sweden)

    Cheung-Chieh Ku

    2015-01-01

    Full Text Available The H2 control scheme and passivity theory are applied to investigate the stability criterion of continuous-time linear stochastic system subject to mixed performance. Based on the stochastic differential equation, the stochastic behaviors can be described as multiplicative noise terms. For the considered system, the H2 control scheme is applied to deal with the problem on minimizing output energy. And the asymptotical stability of the system can be guaranteed under desired initial conditions. Besides, the passivity theory is employed to constrain the effect of external disturbance on the system. Moreover, the Itô formula and Lyapunov function are used to derive the sufficient conditions which are converted into linear matrix inequality (LMI form for applying convex optimization algorithm. Via solving the sufficient conditions, the state feedback controller can be established such that the asymptotical stability and mixed performance of the system are achieved in the mean square. Finally, the synchronous generator system is used to verify the effectiveness and applicability of the proposed design method.

  17. Compositional analysis for linear systems

    NARCIS (Netherlands)

    Kerber, Florian; Schaft, Arjan van der

    2010-01-01

    Compositional analysis techniques such as assume-guarantee reasoning are frequently used in computer science to validate the design of complex process models. Since many engineering systems are built modularly from interconnections of components, the resulting mathematical models can be arbitrarily

  18. Preserving Subject Variability in Group fMRI Analysis: Performance Evaluation of GICA versus IVA

    Directory of Open Access Journals (Sweden)

    Andrew eMichael

    2014-06-01

    Full Text Available Independent component analysis (ICA is a widely applied technique to derive functionally connected brain networks from fMRI data. Group ICA (GICA and Independent Vector Analysis (IVA are extensions of ICA that enable users to perform group fMRI analyses; however a full comparison of the performance limits of GICA and IVA has not been investigated. Recent interest in resting state fMRI data with potentially higher degree of subject variability makes the evaluation of the above techniques important. In this paper we compare component estimation accuracies of GICA and an improved version of IVA using simulated fMRI datasets. We systematically change the degree of component spatial variability and evaluate estimation accuracy over all spatial maps (SMs and time courses (TCs of the decomposition. Our results indicate the following: (1 at low levels of SM variability or when just one SM is varied, both GICA and IVA perform well, (2 at higher levels of SM variability or when more than one SMs are varied, IVA continues to perform well but GICA yields SM estimates that are composites of other SMs with errors in TCs, (3 both GICA and IVA remove spatial correlations of overlapping SMs and introduce artificial correlations in their TCs, (4 if number of SMs is over estimated, IVA continues to perform well but GICA introduces artifacts in the varying and extra SMs with artificial correlations in the TCs of extra components, and (5 in the absence or presence of SMs unique to one subject, GICA produces errors in TCs and IVA estimates are accurate. In summary, our simulation experiments (both simplistic and realistic and our holistic analyses approach indicate that IVA produces results that are closer to ground truth and thereby better preserves subject variability. The improved version of IVA is now packaged into the GIFT toolbox (http://mialab.mrn.org/software/gift.

  19. Slipping and holding minds: A psychosocial analysis of maternal subjectivity in relation to childhood disability.

    Science.gov (United States)

    Young, Lisa Saville; Berry, Jessie

    2016-01-01

    This paper elucidates a methodological approach to interview text that tries to acknowledge the psychosocial nature of disability and thereby ensuring that empirical work in disability studies complements theoretical arguments already developed. The aim of this study is to outline a psychosocial conceptualisation of maternal subjectivity in relation to childhood disability and to apply this conceptualisation as an analytic tool to segments of an interview with a mother of a child with physical and developmental disabilities. Drawing on psychoanalysis and attachment literature alongside critical social psychology we take readers through the analysis of an interview extract with a particular mother. Through a fine grained analysis, we demonstrate the value of attending to the affective processes in and around the text rooted in the particular intersubjective exchange ('here and how') of the interview and the particular socio-historical context ('there and then') in which the mother, child and researcher are located. The reading draws attention to discourses that position this particular mother and her children in particular ways while also pointing to investments in these discourses such that these discourses are not purely social but play affective functions. This paper demonstrates the value of using multiple lenses to read the text, seeking to understand what is going on from within each lens (discursive/social, interpersonal, intrapsychic), while also seeking to disrupt this understanding as we take up the position of a different lens. This approach enables us to hold onto the complexity and locatedness of maternal subjectivity for mothers of children with disabilities.

  20. Hyperthyrotropinaemia in untreated subjects with Down's syndrome aged 6 months to 64 years: a comparative analysis.

    Science.gov (United States)

    Meyerovitch, Joseph; Antebi, Felice; Greenberg-Dotan, Sari; Bar-Tal, Ornit; Hochberg, Ze'ev

    2012-07-01

    To determine whether an altered hypothalamic-pituitary-thyroid axis is inherent to Down's syndrome or if a high level of thyroid-stimulating hormone (TSH) is a feature in a subset of patients with Down's syndrome. Comparative analysis. Major health maintenance organisation (3.8 million insured). A data warehouse search identified all subjects with Down's syndrome who attended Clalit Health Services in 2006 and were tested for TSH and free thyroxine (T4) level on the day of diagnosis (intention-to-treat population). The study group consisted of patients who were not diagnosed with thyroid disease or did not receive thyroid-modulating medication (n=428). Their findings were compared with a control group of healthy age- and sex-matched subjects who were randomly selected from the general population. Distribution of free T4, TSH and total T3 levels. The distribution plot for TSH showed a significant shift of the curve to higher values in the study group compared with the controls (p≤0.0001). This finding held true on further analysis of the whole intention-to-treat population (p95th centile in the presence of normal-range free T4 levels.

  1. Pet Bottle Design, Correlation Analysis Of Pet Bottle Characteristics Subjective Judgment

    Directory of Open Access Journals (Sweden)

    Darko Avramović

    2012-06-01

    Full Text Available Ability to predict consumer’s reaction to particular design solution of the product is very important. Gathering andanalysis of subjective judgments of particular characteristics, based on which the aesthetic of the product is judged,is one of predicting the consumer’s reaction in the future. Knowledge gathered this manner can serve as a referencefor further studies of determining factors for aesthetic results and design quality. There are two opposed opinionsregarding prediction of aesthetic impression. One opinion is that taste of individual cannot be discussed because itis extremely variable and the possibility of meaningful analysis of aesthetic impression is rejected. Other opinionstates that there is a consistent preference of certain aesthetic characteristics despite individual and group differences.Main goal of this paper is to examine the correlation between subjective judgments of certain PET bottlecharacteristics. Analysis showed meaningful correlation between some of the PET bottle characteristics while othercharacteristics showed less correlation. It can be concluded that not all of the characteristics have the same influenceon the aesthetics and design quality of the PET bottle form. Emphasizing the characteristics relative to aesthetics ofthe product can produce better market results, taking in to account that consumer’s buy the product they consider tobe more attractive if other parameters of the product are similar.

  2. Non-linear dynamic instability analysis of thin-walled stiffener beam subjected to uniform harmonic in-plane loading

    Science.gov (United States)

    Yadav, Amit; Panda, Sarat Kumar; Dey, Tanish

    2017-11-01

    Present analysis deals with nonlinear flexural-torsional vibration and dynamic instability of thin-walled stiffener beam with open section subjected to harmonic in-plane loading. The static and dynamic components of the applied harmonic in-plane loading are assumed to vary uniformly. A set of nonlinear partial differential equations (PDEs) describing the vibration of system is derived. Using Galerkin's method, these partial differential equations are reduced into coupled Mathieu equations. The steady state response of the system is determined by solving the condition for a non-trivial solution. The principal regions of parametric resonance are determined using the method suggested by Bolotin. The numerical results are presented to investigate the effect of aspect ratios, boundary conditions and static load factor on the frequency-amplitude responses and instability regions.

  3. A traffic situation analysis system

    Science.gov (United States)

    Sidla, Oliver; Rosner, Marcin

    2011-01-01

    The observation and monitoring of traffic with smart visions systems for the purpose of improving traffic safety has a big potential. For example embedded vision systems built into vehicles can be used as early warning systems, or stationary camera systems can modify the switching frequency of signals at intersections. Today the automated analysis of traffic situations is still in its infancy - the patterns of vehicle motion and pedestrian flow in an urban environment are too complex to be fully understood by a vision system. We present steps towards such a traffic monitoring system which is designed to detect potentially dangerous traffic situations, especially incidents in which the interaction of pedestrians and vehicles might develop into safety critical encounters. The proposed system is field-tested at a real pedestrian crossing in the City of Vienna for the duration of one year. It consists of a cluster of 3 smart cameras, each of which is built from a very compact PC hardware system in an outdoor capable housing. Two cameras run vehicle detection software including license plate detection and recognition, one camera runs a complex pedestrian detection and tracking module based on the HOG detection principle. As a supplement, all 3 cameras use additional optical flow computation in a low-resolution video stream in order to estimate the motion path and speed of objects. This work describes the foundation for all 3 different object detection modalities (pedestrians, vehi1cles, license plates), and explains the system setup and its design.

  4. Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects

    DEFF Research Database (Denmark)

    Andreasen, Anne Sofie; Larsen, Nadja; Pedersen-Skovsgaard, Theis

    2010-01-01

    According to animal studies, intake of probiotic bacteria may improve glucose homeostasis. We hypothesised that probiotic bacteria improve insulin sensitivity by attenuating systemic inflammation. Therefore, the effects of oral supplementation with the probiotic bacterium Lactobacillus acidophilus...... course with either L. acidophilus NCFM or placebo. L. acidophilus was detected in stool samples by denaturating gradient gel electrophoresis and real-time PCR. Separated by the 4-week intervention period, two hyperinsulinaemic-euglycaemic clamps were performed to estimate insulin sensitivity. Furthermore......, the systemic inflammatory response was evaluated by subjecting the participants to Escherichia coli lipopolysaccharide injection (0·3 ng/kg) before and after the treatment course. L. acidophilus NCFM was detected in 75 % of the faecal samples after treatment with the probiotic bacterium. Insulin sensitivity...

  5. Nonlinear dynamic modeling of a simple flexible rotor system subjected to time-variable base motions

    Science.gov (United States)

    Chen, Liqiang; Wang, Jianjun; Han, Qinkai; Chu, Fulei

    2017-09-01

    Rotor systems carried in transportation system or under seismic excitations are considered to have a moving base. To study the dynamic behavior of flexible rotor systems subjected to time-variable base motions, a general model is developed based on finite element method and Lagrange's equation. Two groups of Euler angles are defined to describe the rotation of the rotor with respect to the base and that of the base with respect to the ground. It is found that the base rotations would cause nonlinearities in the model. To verify the proposed model, a novel test rig which could simulate the base angular-movement is designed. Dynamic experiments on a flexible rotor-bearing system with base angular motions are carried out. Based upon these, numerical simulations are conducted to further study the dynamic response of the flexible rotor under harmonic angular base motions. The effects of base angular amplitude, rotating speed and base frequency on response behaviors are discussed by means of FFT, waterfall, frequency response curve and orbits of the rotor. The FFT and waterfall plots of the disk horizontal and vertical vibrations are marked with multiplications of the base frequency and sum and difference tones of the rotating frequency and the base frequency. Their amplitudes will increase remarkably when they meet the whirling frequencies of the rotor system.

  6. Morphometric Analysis of the Mandible in Subjects with Class III Malocclusion

    Directory of Open Access Journals (Sweden)

    Jin-Yun Pan

    2006-07-01

    Full Text Available This study evaluated the deformations that contribute to Class III mandibular configuration, employing geometric morphometric analysis. Lateral cephalograms of male and female groups of 100 young adults and 70 children with Class III malocclusion were compared to those of counterparts with normal occlusion. The sample included an equal number of both genders. The cephalographs were traced, and 12 homologous landmarks were identified and digitized. Average mandibular geometries were generated by means of Procrustes analysis. Thin-plate spline analysis was then applied to mandibular configurations to determine local form differences in male and female groups of adults and children with normal occlusion and Class III malocclusion. The mandibular morphology was significantly different between these two groups of male and female adults, and children (p < 0.0001. This spline analysis revealed an anteroposterior elongation of the mandible along the condylion-gnathion axis, showing an extension in the regions of the mandibular condyle and ramus, and of the anteroinferior portion of the mandibular symphysis in Class III groups. More extension was evident in Class III adults. The deformations in subjects with Class III malocclusion may represent a developmental elongation of the mandible anteroposteriorly, which leads to the appearance of a prognathic mandibular profile.

  7. Subject-enabled analytics model on measurement statistics in health risk expert system for public health informatics.

    Science.gov (United States)

    Chung, Chi-Jung; Kuo, Yu-Chen; Hsieh, Yun-Yu; Li, Tsai-Chung; Lin, Cheng-Chieh; Liang, Wen-Miin; Liao, Li-Na; Li, Chia-Ing; Lin, Hsueh-Chun

    2017-11-01

    This study applied open source technology to establish a subject-enabled analytics model that can enhance measurement statistics of case studies with the public health data in cloud computing. The infrastructure of the proposed model comprises three domains: 1) the health measurement data warehouse (HMDW) for the case study repository, 2) the self-developed modules of online health risk information statistics (HRIStat) for cloud computing, and 3) the prototype of a Web-based process automation system in statistics (PASIS) for the health risk assessment of case studies with subject-enabled evaluation. The system design employed freeware including Java applications, MySQL, and R packages to drive a health risk expert system (HRES). In the design, the HRIStat modules enforce the typical analytics methods for biomedical statistics, and the PASIS interfaces enable process automation of the HRES for cloud computing. The Web-based model supports both modes, step-by-step analysis and auto-computing process, respectively for preliminary evaluation and real time computation. The proposed model was evaluated by computing prior researches in relation to the epidemiological measurement of diseases that were caused by either heavy metal exposures in the environment or clinical complications in hospital. The simulation validity was approved by the commercial statistics software. The model was installed in a stand-alone computer and in a cloud-server workstation to verify computing performance for a data amount of more than 230K sets. Both setups reached efficiency of about 105 sets per second. The Web-based PASIS interface can be used for cloud computing, and the HRIStat module can be flexibly expanded with advanced subjects for measurement statistics. The analytics procedure of the HRES prototype is capable of providing assessment criteria prior to estimating the potential risk to public health. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Analysis of inflammatory cells and mediators in skin wound biopsies to determine wound age in living subjects in forensic medicine.

    Science.gov (United States)

    Fronczek, Judith; Lulf, Ronald; Korkmaz, H Ibrahim; Witte, Birgit I; van de Goot, Franklin R W; Begieneman, Mark P V; Schalkwijk, C G; Krijnen, Paul A J; Rozendaal, Lawrence; Niessen, Hans W M; Reijnders, Udo J L

    2015-02-01

    In forensic medicine it is important to determine the age of skin wounds in living subjects. The aim of this study was to assess whether analysis of inflammatory cells and inflammatory mediators in skin biopsies of wounds from living subjects could improve wound age determination. Biopsies (n=101), representing the superficial border area of a skin wound, were taken from skin injuries of known wound age (range: 4.5 hours to 25 days) of living subjects. All biopsies were analyzed for 3 inflammatory cell markers (MPO, CD45 and CD68) and 4 inflammatory mediators (MIP-1, IL-8, CML and vitronectin). For quantification, biopsies were subdivided in 4 different timeframes: 0.2-2 days, 2-4 days, 4-10 days and 10-25 days old wounds. Subsequently, a probability scoring system was developed. MPO, CD45, MIP-1, IL-8 (inflammatory cell markers) and N(epsilon)-(carboxymethyl)lysine (CML) positivity were maximal in wounds of 0.2-2 days old and then decreased in time. Remarkably, CD45, CD68 and CML showed a minor but non-significant increase again in 10-25 days old wounds. MPO and CD68 positivity was significantly lower in 4-25 days old wounds compared to 0.2-4 days old wounds. MPO positivity was also significantly lower in 10-25 days old wounds compared to 0.2-10 days old wounds. For CD45, MIP-1, IL-8 and CML no significant differences between the age groups were found. In case of vitronectin positivity in the extravasate or when the number of MIP-1 or IL-8-positive cells was more than 10 cells/mm(2) the probability that a wound was more than 10 days old was 0%. A probability scoring system of all analyzed markers can be used to calculate individual wound age probabilities in biopsies of skin wounds of living subjects. We have developed a probability scoring system of inflammatory cells and mediators that can be used to determine wound age in skin biopsies of living subjects. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  9. Doubly Fed Induction Generator Wind Turbine Systems Subject to Recurring Symmetrical Grid Faults

    DEFF Research Database (Denmark)

    Chen, Wenjie; Blaabjerg, Frede; Zhu, Nan

    2016-01-01

    New grid codes demand the wind turbine systems to ride through recurring grid faults. In this paper, the performance of the doubly Ffed induction generator (DFIG) wind turbine system under recurring symmetrical grid faults is analyzed. The mathematical model of the DFIG under recurring symmetrical...... grid faults is established. The analysis is based on the DFIG wind turbine system with the typical low-voltage ride-through strategy-with rotor-side crowbar. The stator natural flux produced by the voltage recovery after the first grid fault may be superposed on the stator natural flux produced...... model of the DFIG under recurring grid faults is verified by simulations on a 1.5-MW DFIG wind turbine system model and experiments on a 30-kW reduced scale DFIG test system....

  10. Study about the subject analysis in children’s literature published in Spain dealing with Physical Education and Sport

    Directory of Open Access Journals (Sweden)

    Rafael Guimarães Botelho

    2012-04-01

    Full Text Available This paper has the aim to investigate the subject of children’s books published in Spain dealing with Physical Education and Sport. To develop the paper, the subject analysis technique was employed. The corpus of analysis, 60 children’s books collected, can be found in the doctoral thesis Physical Education and children’s literature: applications in the scholastic environment (Botelho, 2010. The results obtained in this paper indicated that: (a 30 subjects were identified in the 60 children’s books analysed; (b the subject football presented the great incidence, with 13,33% (eight books; (c the second subject with great incidence is games, with 10,00% (six children’s books; (d the subjects ballet and running had, each one, 8,33% (five books; (e the other subjects registered an inferior incidence of 8% (with 4 or less books; (f the majority of subjects presented an incidence of 1,67% (only one children’s book. The conclusions obtained in this article indicate that: (1 from the 30 subjects identified in the 60 children’s books, the subject football had the great incidence; (2 the majority of subjects presented only one incidence.

  11. Estimation of localization and dipole moment of alpha- and theta-rhythm sources by cluster analysis in healthy subjects and schizophrenics

    NARCIS (Netherlands)

    Verkhlyutov, VM; Shchuchkin, YV; Ushakov, VL; Strelets, VB; Pirogov, YA

    2006-01-01

    In 12 healthy subjects and 9 schizophrenic patients in the background conditions (with eyes closed) EEG was recorded from 16 standard derivations (10-20 system) during 3 min. The record underwent the spectral analysis detecting alpha- and theta-frequency bands. After the preliminary narrow band

  12. (Im) Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis

    NARCIS (Netherlands)

    He, F.; Fromion, V.; Westerhoff, H.V.

    2013-01-01

    Background: Metabolic control analysis (MCA) and supply-demand theory have led to appreciable understanding of the systems properties of metabolic networks that are subject exclusively to metabolic regulation. Supply-demand theory has not yet considered gene-expression regulation explicitly whilst a

  13. Systemic lupus erythematosus patients contain significantly less igm against mono-methylated lysine than healthy subjects.

    Science.gov (United States)

    Guo, Sha; Liu, Ying; Ma, Younan; Zhao, Qing; Zhu, Liping; Shao, Yuehu; Gao, Fengying; Wu, Fengqi; Gao, Ruitong; Zhang, Wei

    2013-01-01

    Post-translational modifications on proteins are important in biological processes but may create neo-epitopes that induce autoimmune responses. In this study, we measured the serum IgG and IgM response to a set of non-modified or acetyl- and methyl-modified peptides corresponding to residues 1-19 of the histone 3 N-terminal tail in systemic lupus erythematosus (SLE) patients and healthy subjects. Our results indicated that the SLE patients and healthy subjects produced antibodies (Abs) to the peptides, but the two groups had different Ab isotype and epitope preferences. Abs to the non-modified form, H31-19, were of the IgG isotype and produced by SLE patients. They could not recognize the scrambled H31-19, which contained the same amino acid composition but a different sequence as H31-19. In comparison, healthy subjects in general did not produce IgG against H31-19. However, about 70% of the healthy subjects produced IgM Abs against mono-methylated K9 of H31-19 (H31-19K9me). Our further studies revealed that ε-amine mono-methylated lysine could completely inhibit the IgM binding to H31-19K9me, but lysine had no inhibitory effect. In addition, the IgM Abs could bind peptides containing a mono-methylated lysine residue but with totally different sequences. Thus, mono-methylated lysine was the sole epitope for the IgM. Interestingly, SLE patients had much lower levels of this type of IgM. There was no obvious correlation between the IgM levels and disease activity and the decreased IgM was unlikely caused by medical treatments.We also found that the IgM Abs were not polyreactive to dsDNA, ssDNA, lipopolysaccharide (LPS) or insulin and they did not exist in umbilical cord serum, implying that they were not natural Abs. The IgM Abs against mono-methylated lysine are present in healthy subjects but are significantly lower in SLE patients, suggesting a distinct origin of production and special physiological functions.

  14. VIBRATION ISOLATION SYSTEM PROBABILITY ANALYSIS

    Directory of Open Access Journals (Sweden)

    Smirnov Vladimir Alexandrovich

    2012-10-01

    Full Text Available The article deals with the probability analysis for a vibration isolation system of high-precision equipment, which is extremely sensitive to low-frequency oscillations even of submicron amplitude. The external sources of low-frequency vibrations may include the natural city background or internal low-frequency sources inside buildings (pedestrian activity, HVAC. Taking Gauss distribution into account, the author estimates the probability of the relative displacement of the isolated mass being still lower than the vibration criteria. This problem is being solved in the three dimensional space, evolved by the system parameters, including damping and natural frequency. According to this probability distribution, the chance of exceeding the vibration criteria for a vibration isolation system is evaluated. Optimal system parameters - damping and natural frequency - are being developed, thus the possibility of exceeding vibration criteria VC-E and VC-D is assumed to be less than 0.04.

  15. A System of Systems Interface Hazard Analysis Technique

    Science.gov (United States)

    2007-03-01

    16 Table 2. HAZOP Process ................................................................................. 21...Table 3. HAZOP Guide Words for Software or System Interface Analysis....... 22 Table 4. Example System of Systems Architecture Table...analysis techniques.28 c. Hazards and Operability Analysis Hazards and Operability ( HAZOP ) Analysis applies a systematic exploration of system

  16. Temperature measurement and control system for transtibial prostheses: Single subject clinical evaluation.

    Science.gov (United States)

    Ghoseiri, Kamiar; Zheng, Yong Ping; Leung, Aaron K L; Rahgozar, Mehdi; Aminian, Gholamreza; Masoumi, Mehdi; Safari, Mohammad Reza

    2017-01-05

    The snug fit of a prosthetic socket over the residual limb can disturb thermal balance and put skin integrity in jeopardy by providing an unpleasant and infectious environment. The prototype of a temperature measurement and control (TM&C) system was previously introduced to resolve thermal problems related to prostheses. This study evaluates its clinical application in a setting with reversal, single subject design. The TM&C system was installed on a fabricated prosthetic socket of a man with unilateral transtibial amputation. Skin temperature of the residual limb without prosthesis at baseline and with prosthesis during rest and walking was evaluated. The thermal sense and thermal comfort of the participant were also evaluated. The results showed different skin temperature around the residual limb with a temperature decrease tendency from proximal to distal. The TM&C system decreased skin temperature rise after prosthesis wearing. The same situation occurred during walking, but the thermal power of the TM&C system was insufficient to overcome heat build-up in some regions of the residual limb. The participant reported no significant change of thermal sense and thermal comfort. Further investigations are warranted to examine thermography pattern of the residual limb, thermal sense, and thermal comfort in people with amputation.

  17. Charging power optimization for nonlinear vibration energy harvesting systems subjected to arbitrary, persistent base excitations

    Science.gov (United States)

    Dai, Quanqi; Harne, Ryan L.

    2018-01-01

    The vibrations of mechanical systems and structures are often a combination of periodic and random motions. Emerging interest to exploit nonlinearities in vibration energy harvesting systems for charging microelectronics may be challenged by such reality due to the potential to transition between favorable and unfavorable dynamic regimes for DC power delivery. Therefore, a need exists to devise an optimization method whereby charging power from nonlinear energy harvesters remains maximized when excitation conditions are neither purely harmonic nor purely random, which have been the attention of past research. This study meets the need by building from an analytical approach that characterizes the dynamic response of nonlinear energy harvesting platforms subjected to combined harmonic and stochastic base accelerations. Here, analytical expressions are formulated and validated to optimize charging power while the influences of the relative proportions of excitation types are concurrently assessed. It is found that about a 2 times deviation in optimal resistive loads can reduce the charging power by 20% when the system is more prominently driven by harmonic base accelerations, whereas a greater proportion of stochastic excitation results in a 11% reduction in power for the same resistance deviation. In addition, the results reveal that when the frequency of a predominantly harmonic excitation deviates by 50% from optimal conditions the charging power reduces by 70%, whereas the same frequency deviation for a more stochastically dominated excitation reduce total DC power by only 20%. These results underscore the need for maximizing direct current power delivery for nonlinear energy harvesting systems in practical operating environments.

  18. Launch vehicle systems design analysis

    Science.gov (United States)

    Ryan, Robert; Verderaime, V.

    1993-01-01

    Current launch vehicle design emphasis is on low life-cycle cost. This paper applies total quality management (TQM) principles to a conventional systems design analysis process to provide low-cost, high-reliability designs. Suggested TQM techniques include Steward's systems information flow matrix method, quality leverage principle, quality through robustness and function deployment, Pareto's principle, Pugh's selection and enhancement criteria, and other design process procedures. TQM quality performance at least-cost can be realized through competent concurrent engineering teams and brilliance of their technical leadership.

  19. A Human Body Analysis System

    Directory of Open Access Journals (Sweden)

    Girondel Vincent

    2006-01-01

    Full Text Available This paper describes a system for human body analysis (segmentation, tracking, face/hands localisation, posture recognition from a single view that is fast and completely automatic. The system first extracts low-level data and uses part of the data for high-level interpretation. It can detect and track several persons even if they merge or are completely occluded by another person from the camera's point of view. For the high-level interpretation step, static posture recognition is performed using a belief theory-based classifier. The belief theory is considered here as a new approach for performing posture recognition and classification using imprecise and/or conflicting data. Four different static postures are considered: standing, sitting, squatting, and lying. The aim of this paper is to give a global view and an evaluation of the performances of the entire system and to describe in detail each of its processing steps, whereas our previous publications focused on a single part of the system. The efficiency and the limits of the system have been highlighted on a database of more than fifty video sequences where a dozen different individuals appear. This system allows real-time processing and aims at monitoring elderly people in video surveillance applications or at the mixing of real and virtual worlds in ambient intelligence systems.

  20. Cytochrome P450 2D6 genotype affects the pharmacokinetics of controlled-release paroxetine in healthy Chinese subjects: comparison of traditional phenotype and activity score systems.

    Science.gov (United States)

    Chen, Rui; Wang, Haotian; Shi, Jun; Shen, Kai; Hu, Pei

    2015-07-01

    This study evaluated the effects of cytochrome P450 (CYP) 2D6 polymorphisms on the pharmacokinetics of controlled-release paroxetine in healthy Chinese subjects and used paroxetine as a tool drug to compare the performance of traditional phenotype and activity score systems. Pharmacokinetic data were evaluated in 24 subjects who received a single oral dose of 25 mg controlled-release paroxetine. Plasma paroxetine concentrations were measured by LC-MS/MS. CYP2D6 genotypes were tested by PCR and direct DNA sequencing. Subjects were classified by two systems of phenotype prediction. In the traditional phenotype system, subjects were classified as extensive metabolizers or intermediate metabolizers; in the activity score system, subjects were divided into four activity groups. Analysis of variance testing was applied to estimate the effects of CYP2D6 polymorphisms on the pharmacokinetics of paroxetine. With the traditional phenotype system, significant differences were observed in the following pharmacokinetic parameters of paroxetine: t 1/2, C max, AUC0-t, AUC0-inf, Vz/F, and CL/F (all P paroxetine was about 3.5-fold higher in the intermediate metabolizer group than in the extensive metabolizer group. With the activity score system, significant differences were observed in the t 1/2, C max, AUC0-t, AUC0-inf, Vz/F, and CL/F among the four different activity score groups (all P paroxetine decreased by around one half as the activity score increased by 0.5. The pharmacokinetics of controlled-release paroxetine after a single administration was affected by CYP2D6 polymorphisms. Both the traditional phenotype and the activity score systems performed well and distinguished subjects with different drug exposures. The activity score system provided a more detailed classification for the subjects.

  1. Factor Analysis of Subjective Psychological Experiences and States of Football Referees

    Directory of Open Access Journals (Sweden)

    Tomáš ZEMAN

    2014-06-01

    Full Text Available Correlations between values of components of subjective psychological experiences and states in 26 male football referees before the match and after the match were explored using factor analysis. For evaluation of subjective psychological experiences and states the standardized questionnaire SUPSO was used. The questionnaire was filled in twice by refer ees: before the match and immediately after the match. Four most important factors were described and named. The first factor was called "tendency to discomfort". It relates to referee ́s current mental state being probably a reflection of long - term negativ e circumstances in referee ́s life. It is neither related to the completed match, nor referee ́s temperament . The second factor was called "depression from failure" and it is connected directly to the completed match. It is probably determined by current ref eree ́s physical and mental conditions . The third and fourth factors proved to be consequences of temperament of referees. In conclusion, the two most important factors of current mental state of football referee during the game can probably be influenced b y a systematic psychological preparation . Psychological preparation should therefore become an effective part of the pre - match preparation of football referees.

  2. Objective analysis versus subjective assessment of vowels pronounced by deaf and normal-hearing children.

    Science.gov (United States)

    Bakkum, M J; Plomp, R; Pols, L W

    1995-08-01

    Objective whole-spectrum and formant analyses have been performed on all 15 Dutch vowels pronounced in /C1VC2/ words by 24 deaf and 24 normal-hearing children, in order to develop a model of pronunciation quality for evaluating (deaf) speech; the results as obtained for adult males by Bakkum et al. [J. Acoust. Soc. Am. 94, 1989-2004 (1993)] have been verified and extended. Spectral representations of the vowels were created by determining the output levels of a bank of 16 filters (90-7200 Hz), with 1/3-oct bandwidths and logarithmic spacing of their center frequencies. Spectral differences agree well with subjective differences in pronunciation quality obtained from magnitude estimation and identification experiments. Spectral differences not related to pronunciation quality judgments arise as a consequence of physiological interspeaker differences and variation in fundamental frequency, but these differences can be compensated for by speaker-normalization and F0-compensation procedures. Using principal components analysis (PCA), the vowel spectra can be described by a limited number of dimensions, without losing much information; a description in a two-dimensional PCA subspace still agrees well with the subjective judgments and it also agrees with a description by the first two formants. The whole-spectrum approach provides a determinate, readily interpretable model of pronunciation quality for evaluating vowels. As a practical advantage, its computational requirements are modest and, in conjunction with PCA, the vowel dynamics can be visualized, which makes the approach suitable for vowel training and diagnostics.

  3. Effect of propofol on the medial temporal lobe emotional memory system: a functional magnetic resonance imaging study in human subjects.

    Science.gov (United States)

    Pryor, K O; Root, J C; Mehta, M; Stern, E; Pan, H; Veselis, R A; Silbersweig, D A

    2015-07-01

    Subclinical doses of propofol produce anterograde amnesia, characterized by an early failure of memory consolidation. It is unknown how propofol affects the amygdala-dependent emotional memory system, which modulates consolidation in the hippocampus in response to emotional arousal and neurohumoral stress. We present an event-related functional magnetic resonance imaging study of the effects of propofol on the emotional memory system in human subjects. Thirty-five healthy subjects were randomized to receive propofol, at an estimated brain concentration of 0.90 μg ml(-1), or placebo. During drug infusion, emotionally arousing and neutral images were presented in a continuous recognition task, while blood-oxygen-level-dependent activation responses were acquired. After a drug-free interval of 2 h, subsequent memory for successfully encoded items was assessed. Imaging analysis was performed using statistical parametric mapping and behavioural analysis using signal detection models. Propofol had no effect on the stereotypical amygdalar response to emotional arousal, but caused marked suppression of the hippocampal response. Propofol caused memory performance to become uncoupled from amygdalar activation, but it remained correlated with activation in the posterior hippocampus, which decreased in proportion to amnesia. Propofol is relatively ineffective at suppressing amygdalar activation at sedative doses, but abolishes emotional modulation and causes amnesia via mechanisms that commonly involve hyporesponsiveness of the hippocampus. These findings raise the possibility that amygdala-dependent fear systems may remain intact even when a patient has diminished memory of events. This may be of clinical importance in the perioperative development of fear-based psychopathologies, such as post-traumatic stress disorder. NCT00504894. © The Author 2015. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions

  4. Evaluation of Subjective and Objective Performance Metrics for Haptically Controlled Robotic Systems

    Directory of Open Access Journals (Sweden)

    Cong Dung Pham

    2014-07-01

    Full Text Available This paper studies in detail how different evaluation methods perform when it comes to describing the performance of haptically controlled mobile manipulators. Particularly, we investigate how well subjective metrics perform compared to objective metrics. To find the best metrics to describe the performance of a control scheme is challenging when human operators are involved; how the user perceives the performance of the controller does not necessarily correspond to the directly measurable metrics normally used in controller evaluation. It is therefore important to study whether there is any correspondence between how the user perceives the performance of a controller, and how it performs in terms of directly measurable metrics such as the time used to perform a task, number of errors, accuracy, and so on. To perform these tests we choose a system that consists of a mobile manipulator that is controlled by an operator through a haptic device. This is a good system for studying different performance metrics as the performance can be determined by subjective metrics based on feedback from the users, and also as objective and directly measurable metrics. The system consists of a robotic arm which provides for interaction and manipulation, which is mounted on a mobile base which extends the workspace of the arm. The operator thus needs to perform both interaction and locomotion using a single haptic device. While the position of the on-board camera is determined by the base motion, the principal control objective is the motion of the manipulator arm. This calls for intelligent control allocation between the base and the manipulator arm in order to obtain intuitive control of both the camera and the arm. We implement three different approaches to the control allocation problem, i.e., whether the vehicle or manipulator arm actuation is applied to generate the desired motion. The performance of the different control schemes is evaluated, and our

  5. “White spots” of the generational analysis: Objective and subjective meaning of the age

    Directory of Open Access Journals (Sweden)

    I V Trotsuk

    2015-12-01

    Full Text Available As a rule, it goes without saying that the generational analysis is one of the major tasks of sociology, which aims to diagnose the state and trends of the social development by comparing value priorities, attitudes and behavioral patterns of the age subgroups that constitute the society. Despite the lack of a common definition of ‘generation’ in the scientific discourse and the differences in its interdisciplinary interpretations researchers agree that in sociology we define ‘generation’ not so much as a demographic group of the same age, but as a certain symbolic community whose members were raised in the similar social conditions. Unfortunately, the Russian sociology adheres to the fragmented version of generational analysis focusing mainly on the youth (less often on the working population as a whole and ‘forgets’ about the elderly and children due to several reasons, but the main ones are evident in both cases - the older generations are largely ignored, and for the youngest it is difficult to choose an adequate methodological approach. The article indicates the thematic priorities of generational analysis in its sociological format (focus on the social status and symbolic features of generations rather than on the culture of childhood, which is the subject of historical research, identifies its key concepts (generation and cohort and problems, summarized the differences of the methodological approaches (primarily quantitative and qualitative and research orientations especially in the study of older ages.

  6. Second-Order Nonlinear Analysis of Steel Tapered Beams Subjected to Span Loading

    Directory of Open Access Journals (Sweden)

    Ali Hadidi

    2014-03-01

    Full Text Available A second-order elastic analysis of tapered steel members with I-shaped sections subjected to span distributed and concentrated loadings is developed. Fixed end forces and moments as well as exact stiffness matrix of tapered Timoshenko-Euler beam are obtained with exact geometrical properties of sections. The simultaneous action of bending moment, shear, and axial force including P−δ effects is also considered in the analysis. A computer code has been developed in MATLAB software using a power series method to solve governing second-order differential equation of equilibrium with variable coefficients for beams with distributed span loading. A generalized matrix condensation technique is then utilized for analysis of beams with concentrated span loadings. The accuracy and efficiency of the results of the proposed method are verified through comparing them to those obtained from other approaches such as finite element methods, which indicates the robustness and time saving of this method even for large scale frames with tapered members.

  7. Empirical Analysis of the Subjective Impressions and Objective Measures of Domain Scientists’ Analytical Judgment Using Visualizations

    Energy Technology Data Exchange (ETDEWEB)

    Dasgupta, Aritra; Burrows, Susannah M.; Han, Kyungsik; Rasch, Philip J.

    2017-04-15

    Scientists working in a particular domain often adhere to conventional data analysis and presentation methods and this leads to familiarity with these methods over time. But does high familiarity always lead to better analytical judgment? This question is especially relevant when visualizations are used in scientific tasks, as there can be discrepancies between visualization best practices and domain conventions. However, there is little empirical evidence of the relationships between scientists’ subjective impressions about familiar and unfamiliar visualizations and objective measures of their effect on scientific judgment. To address this gap and to study these factors, we focus on the climate science domain, specifically on visualizations used for comparison of model performance. We present a comprehensive user study with 47 climate scientists where we explored the following factors: i) relationships between scientists’ familiarity, their perceived levels of com- fort, confidence, accuracy, and objective measures of accuracy, and ii) relationships among domain experience, visualization familiarity, and post-study preference.

  8. Slipping and holding minds: A psychosocial analysis of maternal subjectivity in relation to childhood disability

    Science.gov (United States)

    Berry, Jessie

    2016-01-01

    Background This paper elucidates a methodological approach to interview text that tries to acknowledge the psychosocial nature of disability and thereby ensuring that empirical work in disability studies complements theoretical arguments already developed. Objectives The aim of this study is to outline a psychosocial conceptualisation of maternal subjectivity in relation to childhood disability and to apply this conceptualisation as an analytic tool to segments of an interview with a mother of a child with physical and developmental disabilities. Method Drawing on psychoanalysis and attachment literature alongside critical social psychology we take readers through the analysis of an interview extract with a particular mother. Through a fine grained analysis, we demonstrate the value of attending to the affective processes in and around the text rooted in the particular intersubjective exchange (‘here and how’) of the interview and the particular socio-historical context (‘there and then’) in which the mother, child and researcher are located. Findings The reading draws attention to discourses that position this particular mother and her children in particular ways while also pointing to investments in these discourses such that these discourses are not purely social but play affective functions. Conclusion This paper demonstrates the value of using multiple lenses to read the text, seeking to understand what is going on from within each lens (discursive/social, interpersonal, intrapsychic), while also seeking to disrupt this understanding as we take up the position of a different lens. This approach enables us to hold onto the complexity and locatedness of maternal subjectivity for mothers of children with disabilities. PMID:28730059

  9. Analysis of prototypical narratives produced by aphasic individuals and cognitively healthy subjects

    Directory of Open Access Journals (Sweden)

    Gabriela Silveira

    Full Text Available Aphasia can globally or selectively affect comprehension and production of verbal and written language. Discourse analysis can aid language assessment and diagnosis.Objective:[1] To explore narratives that produce a number of valid indicators for diagnosing aphasia in speakers of Brazilian Portuguese. [2] To analyze the macrostructural aspects of the discourse of normal individuals. [3] To analyze the macrostructural aspects of the discourse of aphasic individuals.Methods:The macrostructural aspects of three narratives produced by aphasic individuals and cognitively healthy subjects were analyzed.Results:A total of 30 volunteers were examined comprising 10 aphasic individuals (AG and 20 healthy controls (CG. The CG included 5 males. The CG had a mean age of 38.9 years (SD=15.61 and mean schooling of 13 years (SD=2.67 whereas the AG had a mean age of 51.7 years (SD=17.3 and mean schooling of 9.1 years (SD=3.69. Participants were asked to narrate three fairy tales as a basis for analyzing the macrostructure of discourse. Comparison of the three narratives revealed no statistically significant difference in number of propositions produced by the groups. A significant negative correlation was found between age and number of propositions produced. Also, statistically significant differences were observed in the number of propositions produced by the individuals in the CG and the AG for the three tales.Conclusion:It was concluded that the three tales are applicable for discourse assessment, containing a similar number of propositions and differentiating aphasic individuals and cognitively healthy subjects based on analysis of the macrostructure of discourse.

  10. Slipping and holding minds: A psychosocial analysis of maternal subjectivity in relation to childhood disability

    Directory of Open Access Journals (Sweden)

    Lisa Saville Young

    2016-02-01

    Full Text Available Background: This paper elucidates a methodological approach to interview text that tries to acknowledge the psychosocial nature of disability and thereby ensuring that empirical work in disability studies complements theoretical arguments already developed.Objectives: The aim of this study is to outline a psychosocial conceptualisation of maternal subjectivity in relation to childhood disability and to apply this conceptualisation as an analytic tool to segments of an interview with a mother of a child with physical and developmental disabilities.Method: Drawing on psychoanalysis and attachment literature alongside critical social psychology we take readers through the analysis of an interview extract with a particular mother. Through a fine grained analysis, we demonstrate the value of attending to the affective processes in and around the text rooted in the particular intersubjective exchange (‘here and how’ of the interview and the particular socio-historical context (‘there and then’ in which the mother, child and researcher are located.Findings: The reading draws attention to discourses that position this particular mother and her children in particular ways while also pointing to investments in these discourses such that these discourses are not purely social but play affective functions.Conclusion: This paper demonstrates the value of using multiple lenses to read the text, seeking to understand what is going on from within each lens (discursive/social, interpersonal, intrapsychic, while also seeking to disrupt this understanding as we take up the position of a different lens. This approach enables us to hold onto the complexity and locatedness of maternal subjectivity for mothers of children with disabilities.

  11. Subjective benefit after BAHA system application in patients with congenital unilateral conductive hearing impairment.

    Science.gov (United States)

    Kunst, Sylvia J W; Hol, Myrthe K S; Mylanus, Emmanuel A M; Leijendeckers, Joop M; Snik, Ad F M; Cremers, Cor W R J

    2008-04-01

    To study whether unilateral Bone-anchored Hearing Aid (BAHA) fitting led to subjective hearing benefit in patients with congenital unilateral conductive hearing impairment. Prospective evaluation on 20 patients. Tertiary referral center. Ten adults and 10 children with congenital unilateral conductive hearing impairment, with a mean air-bone gap of 50 dB, were included. Subjective bilateral hearing benefit after BAHA fitting was measured using 2 disability-specific questionnaires: Chung and Stephens and the Speech, Spatial and Qualities of hearing profile (children's version in the patients aged BAHA fitting. Chung and Stephens' questionnaire showed an overall preference for the BAHA in several specific hearing situations. The Glasgow children's benefit inventory demonstrated an overall mean improvement of +34, which was the most prominent in the learning domain. The 10 adults showed an already good score on the Speech, Spatial and Qualities of hearing scale in the unaided situation. The BAHA was well accepted by most of the patients with congenital unilateral conductive hearing impairment. A preoperative trial of the BAHA system with the BAHA on a headband is part of the preoperative procedure. In children with unilateral conductive hearing loss, with regard to possible childs' development and communication difficulties, intervention with BAHA can be considered as an option.

  12. Markers of sympathetic nervous system activity associate with complex plasma lipids in metabolic syndrome subjects.

    Science.gov (United States)

    Nestel, Paul J; Khan, Anmar A; Straznicky, Nora E; Mellett, Natalie A; Jayawardana, Kaushala; Mundra, Piyushkumar A; Lambert, Gavin W; Meikle, Peter J

    2017-01-01

    Plasma sphingolipids including ceramides, and gangliosides are associated with insulin resistance (IR) through effects on insulin signalling and glucose metabolism. Our studies of subjects with metabolic syndrome (MetS) showed close relationships between IR and sympathetic nervous system (SNS) activity including arterial norepinephrine (NE). We have therefore investigated possible associations of IR and SNS activity with complex lipids that are involved in both insulin sensitivity and neurotransmission. We performed a cross-sectional assessment of 23 lipid classes/subclasses (total 339 lipid species) by tandem mass spectrometry in 94 overweight untreated subjects with IR (quantified by HOMA-IR, Matsuda index and plasma insulin). Independently of IR parameters, several circulating complex lipids associated significantly with arterial NE and NEFA (non-esterified fatty acids) and marginally with heart rate (HR). After accounting for BMI, HOMA-IR, systolic BP, age, gender, and correction for multiple comparisons, these associations were significant (p 0.05) with ceramide, GM3 ganglioside, sphingomyelin, lysophosphatidylcholine, phosphatidylinositol, lysophosphatidylinositol and free cholesterol. Multiple subspecies of these lipids significantly associated with NE and NEFA. None of the IR biomarkers associated significantly with lipid classes/subclasses after correction for multiple comparisons. This is the first demonstration that arterial norepinephrine and NEFA, that reflect both SNS activity and IR, associate significantly with circulating complex lipids independently of IR, suggesting a role for such lipids in neural mechanisms operating in MetS. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  13. Dynamic analysis of an axially moving beam subject to inner pressure using finite element method

    Energy Technology Data Exchange (ETDEWEB)

    Hua, Hongliang; Qiu, Ming; Liao, Zhenqiang [Nanjing University of Science and Technology, Nanjing (China)

    2017-06-15

    A dynamic model of an axially moving flexible beam subject to an inner pressure is present. The coupling principle between a flexible beam and inner pressure is analyzed first, and the potential energy of the inner pressure due to the beam bending is derived using the principle of virtual work. A 1D hollow beam element contain inner pressure is established. The finite element method and Lagrange’s equation are used to derive the motion equations of the axially moving system. The dynamic responses are analyzed by Newmark-β time integration method. Based on the computed dynamic responses, the effects of inner pressure on beam dynamics are discussed. Some interesting phenomenon is observed.

  14. A feedback control system for vibration of magnetostrictive plate subjected to follower force using sinusoidal shear

    Directory of Open Access Journals (Sweden)

    A. Ghorbanpour Arani

    2016-03-01

    Full Text Available In this research, the vibrational behavior of magnetostrictive plate (MsP as a smart component is studied. The plate is subjected to an external follower force and a magnetic field in which the vibration response of MsP has been investigated for both loading combinations. The velocity feedback gain parameter is evaluated to study the effect of magnetic field which is generated by the coil. Sinusoidal shear deformation theory is utilized due to its accuracy of polynomial function with respect to other plate theories. Equations of motion are derived using Hamilton’s principle and solved by differential quadrature method (DQM considering general boundary conditions. The effects of aspect ratio, thickness ratio, follower force and velocity feedback gain are investigated on the frequency response of MsP. Results indicate that magneto-mechanical coupling in MsM helps to control vibrational behaviors of systems such as electro-hydraulic actuator, wireless linear Motors and sensors.

  15. Film analysis systems and applications

    Energy Technology Data Exchange (ETDEWEB)

    Yonekura, Y.; Brill, A.B.

    1981-01-01

    The different components that can be used in modern film analysis systems are reviewed. TV camera and charge-coupled device sensors coupled to computers provide low cost systems for applications such as those described. The autoradiography (ARG) method provides an important tool for medical research and is especially useful for the development of new radiopharmaceutical compounds. Biodistribution information is needed for estimation of radiation dose, and for interpretation of the significance of observed patterns. The need for such precise information is heightened when one seeks to elucidate physiological principles/factors in normal and experimental models of disease. The poor spatial resolution achieved with current PET-imaging systems limits the information on radioreceptor mapping, neutrotransmitter, and neuroleptic drug distribution that can be achieved from patient studies. The artful use of ARG in carefully-controlled animal studies will be required to provide the additional information needed to fully understand results obtained with this new important research tool. (ERB)

  16. Efficient cyclic system to yield ectoine using Brevibacterium sp. JCM 6894 subjected to osmotic downshock.

    Science.gov (United States)

    Nagata, Shinichi; Wang, Yaoqiang; Oshima, Akinobu; Zhang, Linghua; Miyake, Hideyoshi; Sasaki, Hideaki; Ishida, Akio

    2008-03-01

    Brevibacterium sp. JCM 6894 cells grown in the presence of 1.5-2.5 M NaCl for 24 h at 30 degrees C were subjected to the osmotic downshock. Downshocked cells after ectoine release were grown for further 24 h in the fresh medium with same salinity as before shock. When this cyclic system was applied to the strain JCM 6894, the amount of ectoine in the cells increased with an increase of incubation time, which indicates that the cells manipulated by the present conditions were enough active to survive and synthesize ectoine after several times of osmotic downshock. In the presence of 2 M NaCl, the highest yield of ectoine released was achieved in this cyclic system, more than 2.4 g/L during 7 days of incubation. (1)H and (13)C-NMR analyses of solutes released from the cells by the osmotic downshock showed the presence of only ectoine with high purity. Release of ectoine from the cells was carried out within 5 min and its rates were increased by the dilution in the downshock treatment. For the convenience of operations, non-sterilized medium containing 2 M NaCl was examined for the cell growth in the present system, in which almost same level of ectoine yield, release rates, and cell viability were observed as those of sterilized medium. Copyright 2007 Wiley Periodicals, Inc.

  17. A wearable multi-channel fNIRS system for brain imaging in freely moving subjects.

    Science.gov (United States)

    Piper, Sophie K; Krueger, Arne; Koch, Stefan P; Mehnert, Jan; Habermehl, Christina; Steinbrink, Jens; Obrig, Hellmuth; Schmitz, Christoph H

    2014-01-15

    Functional near infrared spectroscopy (fNIRS) is a versatile neuroimaging tool with an increasing acceptance in the neuroimaging community. While often lauded for its portability, most of the fNIRS setups employed in neuroscientific research still impose usage in a laboratory environment. We present a wearable, multi-channel fNIRS imaging system for functional brain imaging in unrestrained settings. The system operates without optical fiber bundles, using eight dual wavelength light emitting diodes and eight electro-optical sensors, which can be placed freely on the subject's head for direct illumination and detection. Its performance is tested on N=8 subjects in a motor execution paradigm performed under three different exercising conditions: (i) during outdoor bicycle riding, (ii) while pedaling on a stationary training bicycle, and (iii) sitting still on the training bicycle. Following left hand gripping, we observe a significant decrease in the deoxyhemoglobin concentration over the contralateral motor cortex in all three conditions. A significant task-related ΔHbO2 increase was seen for the non-pedaling condition. Although the gross movements involved in pedaling and steering a bike induced more motion artifacts than carrying out the same task while sitting still, we found no significant differences in the shape or amplitude of the HbR time courses for outdoor or indoor cycling and sitting still. We demonstrate the general feasibility of using wearable multi-channel NIRS during strenuous exercise in natural, unrestrained settings and discuss the origins and effects of data artifacts. We provide quantitative guidelines for taking condition-dependent signal quality into account to allow the comparison of data across various levels of physical exercise. To the best of our knowledge, this is the first demonstration of functional NIRS brain imaging during an outdoor activity in a real life situation in humans. © 2013.

  18. An Evaluation of a Computer-Based Training on the Visual Analysis of Single-Subject Data

    Science.gov (United States)

    Snyder, Katie

    2013-01-01

    Visual analysis is the primary method of analyzing data in single-subject methodology, which is the predominant research method used in the fields of applied behavior analysis and special education. Previous research on the reliability of visual analysis suggests that judges often disagree about what constitutes an intervention effect. Considering…

  19. Simulation modelling analysis for small sets of single-subject data collected over time.

    Science.gov (United States)

    Borckardt, Jeffrey J; Nash, Michael R

    2014-01-01

    The behavioural data yielded by single subjects in naturalistic and controlled settings likely contain valuable information to scientists and practitioners alike. Although some of the properties unique to this data complicate statistical analysis, progress has been made in developing specialised techniques for rigorous data evaluation. There are no perfect tests currently available to analyse short autocorrelated data streams, but there are some promising approaches that warrant further development. Although many approaches have been proposed, and some appear better than others, they all have some limitations. When data sets are large enough (∼30 data points per phase), the researcher has a reasonably rich pallet of statistical tools from which to choose. However, when the data set is sparse, the analytical options dwindle. Simulation modelling analysis (SMA; described in this article) is a relatively new technique that appears to offer acceptable Type-I and Type-II error rate control with short streams of autocorrelated data. However, at this point, it is probably too early to endorse any specific statistical approaches for short, autocorrelated time-series data streams. While SMA shows promise, more work is needed to verify that it is capable of reliable Type-I and Type-II error performance with short serially dependent streams of data.

  20. Research and Development on Automatic Information Organization and Subject Analysis in Recent Decades

    Directory of Open Access Journals (Sweden)

    Yuen-Hsien Tseng

    2014-10-01

    Full Text Available Information organization and subject analysis (IOSA is an important issue in the field of library and information science(LIS.As the fast advance in information technology, more and more digital documents are emerging in a pace such that automated IOSA become inevitable. This article firstly introduces the development of related automatic techniques in recent decades and promotes a tranditional viewpoint based on the workflow of:(1 data collection and aggregation, (2 cataloguing, (3 regulation, (4 archving, and (5 usage,to regulate the whole process when applying automated techniques to any IOSA task.Some application examples are then described to let the readers have a feel of the feasibility of these techniques; specifically the applications of keyword extraction, association analysis, document clustering, and topic categorization are mentioned.We conclude that the related techniques and applications are still developing in a quick pace such that only a few percentages of them can be mentioned.This article is intended to promote the mutual cooperation among the LIS and other fields.

  1. Cultural, social and personal ways of experiencing love - an analysis of the perception of subjectivity.

    Science.gov (United States)

    Gori, Claudia

    2011-11-01

    This article is based on analysis of 4 couple's personal and public documents, in order to integrate personal choices, values and ideas with cultural representations and social attitudes. Moreover, being based on Italian sources from the nineteenth century, the study offers an historical insight on the Italian nation-building process and its political and social foundations. This study is based on archival and printed primary sources from: Gianna Maffei and Ercole Trotti Mosti (Museo Centrale del Risorgimento - Roma - MCRR); Augusto Pierantoni and Grazia Mancini (Museo Centrale del Risorgimento - Roma); Luigi Majno and Ersilia Bronzini (Archivio Unione Femminile Nazionale - Milano); Angiolo Orvieto and Laura Cantoni (Archivio Contemporaneo Bonsanti del Gabinetto Vieuesseux - Firenze - ACGV). This study reflects on love as a political and moral issue, by linking the personal sphere of subjectivity to the public dimension of the political community. An extensive understanding of the role played by the perception and the expression of sentiments can be considered as the central issue of this analysis.

  2. Cultural, social and personal ways of experiencing love – an analysis of the perception of subjectivity

    Science.gov (United States)

    Gori, Claudia

    2011-01-01

    Summary This article is based on analysis of 4 couple’s personal and public documents, in order to integrate personal choices, values and ideas with cultural representations and social attitudes. Moreover, being based on Italian sources from the nineteenth century, the study offers an historical insight on the Italian nation-building process and its political and social foundations. This study is based on archival and printed primary sources from: Gianna Maffei and Ercole Trotti Mosti (Museo Centrale del Risorgimento – Roma – MCRR); Augusto Pierantoni and Grazia Mancini (Museo Centrale del Risorgimento – Roma); Luigi Majno and Ersilia Bronzini (Archivio Unione Femminile Nazionale – Milano); Angiolo Orvieto and Laura Cantoni (Archivio Contemporaneo Bonsanti del Gabinetto Vieuesseux – Firenze – ACGV). This study reflects on love as a political and moral issue, by linking the personal sphere of subjectivity to the public dimension of the political community. An extensive understanding of the role played by the perception and the expression of sentiments can be considered as the central issue of this analysis. PMID:22037756

  3. Automation for System Safety Analysis

    Science.gov (United States)

    Malin, Jane T.; Fleming, Land; Throop, David; Thronesbery, Carroll; Flores, Joshua; Bennett, Ted; Wennberg, Paul

    2009-01-01

    This presentation describes work to integrate a set of tools to support early model-based analysis of failures and hazards due to system-software interactions. The tools perform and assist analysts in the following tasks: 1) extract model parts from text for architecture and safety/hazard models; 2) combine the parts with library information to develop the models for visualization and analysis; 3) perform graph analysis and simulation to identify and evaluate possible paths from hazard sources to vulnerable entities and functions, in nominal and anomalous system-software configurations and scenarios; and 4) identify resulting candidate scenarios for software integration testing. There has been significant technical progress in model extraction from Orion program text sources, architecture model derivation (components and connections) and documentation of extraction sources. Models have been derived from Internal Interface Requirements Documents (IIRDs) and FMEA documents. Linguistic text processing is used to extract model parts and relationships, and the Aerospace Ontology also aids automated model development from the extracted information. Visualizations of these models assist analysts in requirements overview and in checking consistency and completeness.

  4. Large-scale international validation of the ADO index in subjects with COPD: an individual subject data analysis of 10 cohorts

    Science.gov (United States)

    Puhan, Milo A; Hansel, Nadia N; Sobradillo, Patricia; Enright, Paul; Lange, Peter; Hickson, DeMarc; Menezes, Ana M; ter Riet, Gerben; Held, Ulrike; Domingo-Salvany, Antonia; Mosenifar, Zab; Antó, Josep M; Moons, Karel G M; Kessels, Alphons; Garcia-Aymerich, Judith

    2012-01-01

    Background Little evidence on the validity of simple and widely applicable tools to predict mortality in patients with chronic obstructive pulmonary disease (COPD) exists. Objective To conduct a large international study to validate the ADO index that uses age, dyspnoea and FEV1 to predict 3-year mortality and to update it in order to make prediction of mortality in COPD patients as generalisable as possible. Design Individual subject data analysis of 10 European and American cohorts (n=13 914). Setting Population-based, primary, secondary and tertiary care. Patients COPD GOLD stages I–IV. Measurements We validated the original ADO index. We then obtained an updated ADO index in half of our cohorts to improve its predictive accuracy, which in turn was validated comprehensively in the remaining cohorts using discrimination, calibration and decision curve analysis and a number of sensitivity analyses. Results 1350 (9.7%) of all subjects with COPD (60% male, mean age 61 years, mean FEV1 66% predicted) had died at 3 years. The original ADO index showed high discrimination but poor calibration (p<0.001 for difference between predicted and observed risk). The updated ADO index (scores from 0 to 14) preserved excellent discrimination (area under curve 0.81, 95% CI 0.80 to 0.82) but showed much improved calibration with predicted 3-year risks from 0.7% (95% CI 0.6% to 0.9%, score of 0) to 64.5% (61.2% to 67.7%, score of 14). The ADO index showed higher net benefit in subjects at low-to-moderate risk of 3-year mortality than FEV1 alone. Interpretation The updated 15-point ADO index accurately predicts 3-year mortality across the COPD severity spectrum and can be used to inform patients about their prognosis, clinical trial study design or benefit harm assessment of medical interventions. PMID:23242246

  5. Biomechanical analysis and modeling of different vertebral growth patterns in adolescent idiopathic scoliosis and healthy subjects

    Directory of Open Access Journals (Sweden)

    Driscoll Mark

    2011-05-01

    Full Text Available Abstract Background The etiology of AIS remains unclear, thus various hypotheses concerning its pathomechanism have been proposed. To date, biomechanical modeling has not been used to thoroughly study the influence of the abnormal growth profile (i.e., the growth rate of the vertebral body during the growth period on the pathomechanism of curve progression in AIS. This study investigated the hypothesis that AIS progression is associated with the abnormal growth profiles of the anterior column of the spine. Methods A finite element model of the spinal column including growth dynamics was utilized. The initial geometric models were constructed from the bi-planar radiographs of a normal subject. Based on this model, five other geometric models were generated to emulate different coronal and sagittal curves. The detailed modeling integrated vertebral body growth plates and growth modulation spinal biomechanics. Ten years of spinal growth was simulated using AIS and normal growth profiles. Sequential measures of spinal alignments were compared. Results (1 Given the initial lateral deformity, the AIS growth profile induced a significant Cobb angle increase, which was roughly between three to five times larger compared to measures utilizing a normal growth profile. (2 Lateral deformities were absent in the models containing no initial coronal curvature. (3 The presence of a smaller kyphosis did not produce an increase lateral deformity on its own. (4 Significant reduction of the kyphosis was found in simulation results of AIS but not when using the growth profile of normal subjects. Conclusion Results from this analysis suggest that accelerated growth profiles may encourage supplementary scoliotic progression and, thus, may pose as a progressive risk factor.

  6. Diagnosis and Classification of 17 Diseases from 1404 Subjects via Pattern Analysis of Exhaled Molecules.

    Science.gov (United States)

    Nakhleh, Morad K; Amal, Haitham; Jeries, Raneen; Broza, Yoav Y; Aboud, Manal; Gharra, Alaa; Ivgi, Hodaya; Khatib, Salam; Badarneh, Shifaa; Har-Shai, Lior; Glass-Marmor, Lea; Lejbkowicz, Izabella; Miller, Ariel; Badarny, Samih; Winer, Raz; Finberg, John; Cohen-Kaminsky, Sylvia; Perros, Frédéric; Montani, David; Girerd, Barbara; Garcia, Gilles; Simonneau, Gérald; Nakhoul, Farid; Baram, Shira; Salim, Raed; Hakim, Marwan; Gruber, Maayan; Ronen, Ohad; Marshak, Tal; Doweck, Ilana; Nativ, Ofer; Bahouth, Zaher; Shi, Da-You; Zhang, Wei; Hua, Qing-Ling; Pan, Yue-Yin; Tao, Li; Liu, Hu; Karban, Amir; Koifman, Eduard; Rainis, Tova; Skapars, Roberts; Sivins, Armands; Ancans, Guntis; Liepniece-Karele, Inta; Kikuste, Ilze; Lasina, Ieva; Tolmanis, Ivars; Johnson, Douglas; Millstone, Stuart Z; Fulton, Jennifer; Wells, John W; Wilf, Larry H; Humbert, Marc; Leja, Marcis; Peled, Nir; Haick, Hossam

    2017-01-24

    We report on an artificially intelligent nanoarray based on molecularly modified gold nanoparticles and a random network of single-walled carbon nanotubes for noninvasive diagnosis and classification of a number of diseases from exhaled breath. The performance of this artificially intelligent nanoarray was clinically assessed on breath samples collected from 1404 subjects having one of 17 different disease conditions included in the study or having no evidence of any disease (healthy controls). Blind experiments showed that 86% accuracy could be achieved with the artificially intelligent nanoarray, allowing both detection and discrimination between the different disease conditions examined. Analysis of the artificially intelligent nanoarray also showed that each disease has its own unique breathprint, and that the presence of one disease would not screen out others. Cluster analysis showed a reasonable classification power of diseases from the same categories. The effect of confounding clinical and environmental factors on the performance of the nanoarray did not significantly alter the obtained results. The diagnosis and classification power of the nanoarray was also validated by an independent analytical technique, i.e., gas chromatography linked with mass spectrometry. This analysis found that 13 exhaled chemical species, called volatile organic compounds, are associated with certain diseases, and the composition of this assembly of volatile organic compounds differs from one disease to another. Overall, these findings could contribute to one of the most important criteria for successful health intervention in the modern era, viz. easy-to-use, inexpensive (affordable), and miniaturized tools that could also be used for personalized screening, diagnosis, and follow-up of a number of diseases, which can clearly be extended by further development.

  7. The ATLAS distributed analysis system

    Science.gov (United States)

    Legger, F.; Atlas Collaboration

    2014-06-01

    In the LHC operations era, analysis of the multi-petabyte ATLAS data sample by globally distributed physicists is a challenging task. To attain the required scale the ATLAS Computing Model was designed around the concept of Grid computing, realized in the Worldwide LHC Computing Grid (WLCG), the largest distributed computational resource existing in the sciences. The ATLAS experiment currently stores over 140 PB of data and runs about 140,000 concurrent jobs continuously at WLCG sites. During the first run of the LHC, the ATLAS Distributed Analysis (DA) service has operated stably and scaled as planned. More than 1600 users submitted jobs in 2012, with 2 million or more analysis jobs per week, peaking at about a million jobs per day. The system dynamically distributes popular data to expedite processing and maximally utilize resources. The reliability of the DA service is high and steadily improving; Grid sites are continually validated against a set of standard tests, and a dedicated team of expert shifters provides user support and communicates user problems to the sites. Both the user support techniques and the direct feedback of users have been effective in improving the success rate and user experience when utilizing the distributed computing environment. In this contribution a description of the main components, activities and achievements of ATLAS distributed analysis is given. Several future improvements being undertaken will be described.

  8. Validation of analysis methods for assessing flawed piping subjected to dynamic loading

    Energy Technology Data Exchange (ETDEWEB)

    Olson, R.J.; Wolterman, R.L.; Wilkowski, G.M. [Battelle, Columbus, OH (United States); Kot, C.A. [Argonne National Lab., IL (United States)

    1994-08-01

    Argonne National Laboratory and Battelle have jointly conducted a research program for the USNRC to evaluate the ability of current engineering analysis methods and one state-of-the-art analysis method to predict the behavior of circumferentially surface-cracked pipe system water-hammer experiment. The experimental data used in the evaluation were from the HDR Test Group E31 series conducted by the Kernforschungszentrum Karlsruhe (KfK) in Germany. The incentive for this evaluation was that simplified engineering methods, as well as newer ``state-of-the-art`` fracture analysis methods, have been typically validated only with static experimental data. Hence, these dynamic experiments were of high interest. High-rate dynamic loading can be classified as either repeating, e.g., seismic, or nonrepeating, e.g., water hammer. Development of experimental data and validation of cracked pipe analyses under seismic loading (repeating dynamic loads) are being pursued separately within the NRC`s International Piping Integrity Research Group (IPIRG) program. This report describes developmental and validation efforts to predict crack stability under water hammer loading, as well as comparisons using currently used analysis procedures. Current fracture analysis methods use the elastic stress analysis loads decoupled from the fracture mechanics analysis, while state-of-the-art methods employ nonlinear cracked-pipe time-history finite element analyses. The results showed that the current decoupled methods were conservative in their predictions, whereas the cracked pipe finite element analyses were more accurate, yet slightly conservative. The nonlinear time-history cracked-pipe finite element analyses conducted in this program were also attractive in that they were done on a small Apollo DN5500 workstation, whereas other cracked-pipe dynamic analyses conducted in Europe on the same experiments required the use of a CRAY2 supercomputer, and were less accurate.

  9. Analysis of oil-pipeline distribution of multiple products subject to delivery time-windows

    Science.gov (United States)

    Jittamai, Phongchai

    This dissertation defines the operational problems of, and develops solution methodologies for, a distribution of multiple products into oil pipeline subject to delivery time-windows constraints. A multiple-product oil pipeline is a pipeline system composing of pipes, pumps, valves and storage facilities used to transport different types of liquids. Typically, products delivered by pipelines are petroleum of different grades moving either from production facilities to refineries or from refineries to distributors. Time-windows, which are generally used in logistics and scheduling areas, are incorporated in this study. The distribution of multiple products into oil pipeline subject to delivery time-windows is modeled as multicommodity network flow structure and mathematically formulated. The main focus of this dissertation is the investigation of operating issues and problem complexity of single-source pipeline problems and also providing solution methodology to compute input schedule that yields minimum total time violation from due delivery time-windows. The problem is proved to be NP-complete. The heuristic approach, a reversed-flow algorithm, is developed based on pipeline flow reversibility to compute input schedule for the pipeline problem. This algorithm is implemented in no longer than O(T·E) time. This dissertation also extends the study to examine some operating attributes and problem complexity of multiple-source pipelines. The multiple-source pipeline problem is also NP-complete. A heuristic algorithm modified from the one used in single-source pipeline problems is introduced. This algorithm can also be implemented in no longer than O(T·E) time. Computational results are presented for both methodologies on randomly generated problem sets. The computational experience indicates that reversed-flow algorithms provide good solutions in comparison with the optimal solutions. Only 25% of the problems tested were more than 30% greater than optimal values and

  10. Regulation of lipolysis by the sympathetic nervous system: a microdialysis study in normal and spinal cord-injured subjects.

    Science.gov (United States)

    Karlsson, A K; Elam, M; Friberg, P; Biering-Sörensen, F; Sullivan, L; Lönnroth, P

    1997-04-01

    To evaluate the regulation of lipolysis by the sympathetic nervous system, eight spinal cord-injured (SCI) subjects with a lesion above T5 resulting in a decentralization of the lower-body sympathetic nervous system and adrenal medulla (age, 36 +/- 2 years; weight, 82 +/- 5 kg; body fat mass, 26.8 +/- 3.0 kg; all mean +/- SE) and nine control subjects (age, 33 +/- 2; weight, 80 +/- 3; NS; body fat mass, 16.1 +/- 1.5 kg; P exercise. SCI subjects had an increased body fat mass, hyperinsulinemia, and an elevated lipolytic rate at rest compared with control subjects. ATBF and lipolysis were activated to a normal extent following mental stress and isometric handgrip exercise in the umbilical region in control subjects. ATBF was increased in tissue above but not below the lesion level in SCI subjects following mental stress. Glycerol release was not different between groups in either tissue region despite significantly lower noradrenaline and adrenaline levels in SCI subjects. This finding argues against a significant adrenergic control of the lipolytic rate at rest. Furthermore, the small differences in stimulated glycerol release between groups, as well as the increased plasma glycerol levels in SCI subjects, cast doubt on the view that interruption of adrenergic activity below the lesion is the sole mechanism underlying the increased body fat mass in SCI subjects.

  11. Stability analysis of nonlinear systems

    CERN Document Server

    Lakshmikantham, Vangipuram; Martynyuk, Anatoly A

    2015-01-01

    The book investigates stability theory in terms of two different measure, exhibiting the advantage of employing families of Lyapunov functions and treats the theory of a variety of inequalities, clearly bringing out the underlying theme. It also demonstrates manifestations of the general Lyapunov method, showing how this technique can be adapted to various apparently diverse nonlinear problems. Furthermore it discusses the application of theoretical results to several different models chosen from real world phenomena, furnishing data that is particularly relevant for practitioners. Stability Analysis of Nonlinear Systems is an invaluable single-sourse reference for industrial and applied mathematicians, statisticians, engineers, researchers in the applied sciences, and graduate students studying differential equations.

  12. Validation of subject-specific cardiovascular system models from porcine measurements.

    Science.gov (United States)

    Revie, James A; Stevenson, David J; Chase, J Geoffrey; Hann, Christopher E; Lambermont, Bernard C; Ghuysen, Alexandre; Kolh, Philippe; Shaw, Geoffrey M; Heldmann, Stefan; Desaive, Thomas

    2013-02-01

    A previously validated mathematical model of the cardiovascular system (CVS) is made subject-specific using an iterative, proportional gain-based identification method. Prior works utilised a complete set of experimentally measured data that is not clinically typical or applicable. In this paper, parameters are identified using proportional gain-based control and a minimal, clinically available set of measurements. The new method makes use of several intermediary steps through identification of smaller compartmental models of CVS to reduce the number of parameters identified simultaneously and increase the convergence stability of the method. This new, clinically relevant, minimal measurement approach is validated using a porcine model of acute pulmonary embolism (APE). Trials were performed on five pigs, each inserted with three autologous blood clots of decreasing size over a period of four to five hours. All experiments were reviewed and approved by the Ethics Committee of the Medical Faculty at the University of Liege, Belgium. Continuous aortic and pulmonary artery pressures (P(ao), P(pa)) were measured along with left and right ventricle pressure and volume waveforms. Subject-specific CVS models were identified from global end diastolic volume (GEDV), stroke volume (SV), P(ao), and P(pa) measurements, with the mean volumes and maximum pressures of the left and right ventricles used to verify the accuracy of the fitted models. The inputs (GEDV, SV, P(ao), P(pa)) used in the identification process were matched by the CVS model to errors pressures not used to fit the model compared experimental measurements to median absolute errors of 4.3% and 4.4%, which are equivalent to the measurement errors of currently used monitoring devices in the ICU (∼5-10%). These results validate the potential for implementing this approach in the intensive care unit. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  13. Discourse, Subject, and Agency. Linking Discourse Analysis and Biographical Research with the Help of the Concept of Articulation

    Directory of Open Access Journals (Sweden)

    Tina Spies

    2009-04-01

    Full Text Available For a significant period of time biographical research did not focus on the influence of discourses on biographical narratives. In contrast, discourse analysis often disregarded the subject-constituting impact of discourses. This article deals with the theoretical question of how to work with both: discourse and subject. Therefore, I will introduce Stuart HALL's concept of articulation. Since the early 1990's HALL has been working on questions of (cultural identity. In this context he developed an understanding of subjects that enables them not only to be seen as effects of discourses, but also allows focusing on discourses in subject conceptions. Neither biographical research nor discourse analysis In German speaking countries have embraced the work of HALL. But his concept of articulation could link biographical research and discourse analysis, and could also be used for further empirical work. URN: urn:nbn:de:0114-fqs0902369

  14. Does Whole-Body Vibration Improve the Functional Exercise Capacity of Subjects With COPD? A Meta-Analysis.

    Science.gov (United States)

    Cardim, Adriane B; Marinho, Patrícia Em; Nascimento, Jasiel F; Fuzari, Helen Kb; Dornelas de Andrade, Armèle

    2016-11-01

    Whole-body vibration (WBV) is considered a type of physical activity based on the assumption that it results in an increase in muscle strength and performance and, therefore, may be a promising way to exercise patients with COPD. A comprehensive database search (PubMed/MEDLINE, LILACS, CINAHL, Web of Science, Scopus, and COCHRANE Library) for randomized trials, including original articles, that compared WBV groups versus control groups was conducted and studies were selected for comparison. The effect of WBV treatment was compared for minimum clinically important differences. The statistical heterogeneity among the studies was assessed using the I2 statistic; the results are expressed as percentages. Inconsistencies of up to 25% were considered low, those between 50 and 75% were considerate moderate, and those > 75% were considered high. Risk of bias was classified based on the Cochrane Collaboration tool, the meta-analysis was conducted using RevMan 5.3 software, and the level of evidence was assessed using the GRADE system. The primary outcome was functional exercise capacity. Secondary outcomes were quality of life, performance in activities of daily living, muscle strength of the lower limbs, and possible adverse effects assessed clinically or by subject reports. We included 4 articles involving 185 subjects for analysis. All subjects in the groups undergoing WBV showed improvement in distance walked in the 6-min walk test compared with the control group (57.85 m, 95% CI 16.36-99.33 m). Regarding the secondary end points, just one article reported improved quality of life and activities of daily living. The only article that assessed muscle strength found no difference between the groups. The quality of evidence for functional exercise capacity outcome was considered moderate. WBV seems to benefit subjects with COPD by improving their functional exercise capacity, without producing adverse effects. The quality of evidence is moderate, but the degree of

  15. Glucosamine-containing supplement improves locomotor functions in subjects with knee pain – a pilot study of gait analysis

    Directory of Open Access Journals (Sweden)

    Kanzaki N

    2016-06-01

    Full Text Available Noriyuki Kanzaki,1 Yuta Otsuka,1 Takayuki Izumo,1 Hiroshi Shibata,1 Hideyuki Nagao,2 Keita Ogawara,3 Hiroshi Yamada,3 Seiji Miyazaki,3 Yutaka Nakamura3 1Institute for Health Care Science, Suntory Wellness Ltd, Seika-cho, Soraku-gun, Kyoto, Japan; 2Research Institute of Sports Medical Science, Tokai University, Hiratsuka, Kanagawa, Japan; 3School of Physical Education, Tokai University, Hiratsuka, Kanagawa, Japan Background: Previously, we demonstrated that glucosamine-containing supplementation was effective for improving locomotor functions, especially walking speed. However, the biomechanical mechanism of efficacy has not been elucidated. This study aimed to address this challenge in subjects with knee pain, using a motion capture system. Methods: An open label study was conducted in 30 Japanese subjects with knee pain. The subjects were administered a daily supplement containing 1,200 mg of glucosamine hydrochloride, 60 mg of chondroitin sulfate, 45 mg of type II collagen peptides, 90 mg of quercetin glycosides, 10 mg of imidazole peptides, 1 mg of proteoglycan, and 5 µg of vitamin D (GCQID. The intervention continued for 16 weeks. Efficacy for locomotor functions involving the knee joint was evaluated mainly using the Japanese Knee Osteoarthritis Measure (JKOM and the 5-question Geriatric Locomotive Function Scale (GLFS-5. To examine the biomechanical mechanism of efficacy for locomotor functions, motions of subjects in a normal walking state were captured. Gait analysis was conducted and efficacy for gait parameters such as normal walking speed, stride length, cadence, and angle of soles was evaluated. Results: GCQID significantly improved total scores on the JKOM and GLFS-5. In gait analysis, normal walking speed, stride length, and angle of soles at the end of the stance phase were all significantly increased, but cadence did not change significantly during the intervention period. There were significant intercorrelations of changes in

  16. Fluid-Structure Interaction Analysis for Pressurizer Surge Line subjected to Thermal Stratification

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dong Gu; Jhung, Myung Jo; Yang, Chae Yong [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2012-05-15

    Fluid-Structure Interactions (FSIs) occurring inevitably in operating reactor component systems can cause excessive force or stress to the structures resulting in mechanical damages that may eventually threaten the structural integrity of components. To solve FSI problems, results from one field (fluid-thermal) analysis are applied as loads in other fields (structural) analysis. If two media with different densities flow inside a pipe, thermal stratification can occur. Warm water is lighter than cool water and therefore tends to float on top of the cooler and heavier water, resulting in the upper portion of the pipe being hotter than the lower portion. Under these conditions, differential thermal expansion of the pipe metal can cause the pipe to deflect significantly. Unexpected piping movements are highly undesirable because of potential high piping stress that may exceed design limits for fatigue and stress. In PWRs, there are great possibilities of occurrence of thermal stratification at the feed water lines of the steam generator, at the pressurizer surge line and at the injection pipes of the emergency core cooling systems. The most affected pipe by the thermal stratification is reported to be the pressurizer surge line. Therefore in this study, a thermal-stress simulation is performed using ANSYS FSI. For the pressurizer surge line, thermal loads are transferred from ANSYS CFX to ANSYS Multiphysics in order to determine the heat transfer between the fluid and the solid body. From this information, stresses are determined and ultimately a fatigue analysis is performed

  17. SUBJECT INDEX

    Indian Academy of Sciences (India)

    Subject Index. Variation of surface electric field during geomagnetic disturbed period at Maitri, Antarctica. 1721. Geomorphology. A simple depression-filling method for raster and irregular elevation datasets. 1653. Decision Support System integrated with Geographic. Information System to target restoration actions in water-.

  18. LTP-like plasticity in the visual system and in the motor system appear related in young and healthy subjects

    Directory of Open Access Journals (Sweden)

    Stefan eKlöppel

    2015-09-01

    Full Text Available LTP-like plasticity measured by visual evoked potentials (VEP can be induced in the intact human brain by presenting checkerboard reversals. Also associated with LTP-like plasticity, around two third of participants respond to transcranial magnetic stimulation with a paired-associate stimulation (PAS protocol with a potentiation of their motor evoked potentials. LTP-like processes are also required for verbal and motor learning tasks. We compared effect sizes, responder rates and intercorrelations as well as the potential influence of attention between these four assessments in a group of 37 young and healthy volunteers. We observed a potentiation effect of the N75 and P100 VEP component which positively correlated with plasticity induced by PAS. Subjects with a better subjective alertness were more likely to show PAS and VEP potentiation. No correlation was found between the other assessments. Effect sizes and responder rates of VEP potentiation were higher compared to PAS. Our results indicate a high variability of LTP-like effects and no evidence for a system-specific nature. As a consequence, studies wishing to assess individual levels of LTP-like plasticity should employ a combination of multiple assessments.

  19. A Statistical Method and Tool to Account for Indirect Calorimetry Differential Measurement Error in a Single-Subject Analysis.

    Science.gov (United States)

    Tenan, Matthew S

    2016-01-01

    Indirect calorimetry and oxygen consumption (VO2) are accepted tools in human physiology research. It has been shown that indirect calorimetry systems exhibit differential measurement error, where the error of a device is systematically different depending on the volume of gas flow. Moreover, systems commonly report multiple decimal places of precision, giving the clinician a false sense of device accuracy. The purpose of this manuscript is to demonstrate the use of a novel statistical tool which models the reliability of two specific indirect calorimetry systems, Douglas bag and Parvomedics 2400 TrueOne, as univariate normal distributions and implements the distribution overlapping coefficient to determine the likelihood that two VO2 measures are the same. A command line implementation of the tool is available for the R programming language as well as a web-based graphical user interface (GUI). This tool is valuable for clinicians performing a single-subject analysis as well as researchers interested in determining if their observed differences exceed the error of the device.

  20. Fatigue Analysis of a Point Absorber WEC subjected to Passive and Reactive Control

    DEFF Research Database (Denmark)

    Zurkinden, Andrew Stephen; Lambertsen, Søren Heide; Damkilde, Lars

    2015-01-01

    and generic toolbox which can be applied to any other global response model of a WEC device combined with a control system. The stress responses due to the stochastic wave loads are computed by a FEM model using the frequency-domain approach. The fatigue damage is calculated based on the spectral......-based fatigue analysis in which the fatigue is described by the given spectral moments of the stress response. The question will be discussed, which control case is more favorable regarding the trade off between fatigue damage reduction and increased power production....

  1. Rethinking the process of operational research & systems analysis

    CERN Document Server

    Tomlinson, R

    1984-01-01

    Invited contributions from distinguished practitioners and methodologists of operational research and applied systems analysis which represent a true state-of-the-art and which provide, perhaps for the first time, a coherent, interlocking, set of ideas which may be considered the foundations of the subject as a science in its own right.

  2. Intelligent Tutoring Systems and Learning Outcomes: A Meta-Analysis

    Science.gov (United States)

    Ma, Wenting; Adesope, Olusola O.; Nesbit, John C.; Liu, Qing

    2014-01-01

    Intelligent Tutoring Systems (ITS) are computer programs that model learners' psychological states to provide individualized instruction. They have been developed for diverse subject areas (e.g., algebra, medicine, law, reading) to help learners acquire domain-specific, cognitive and metacognitive knowledge. A meta-analysis was conducted on…

  3. The ATLAS Distributed Analysis System

    CERN Document Server

    Legger, F; The ATLAS collaboration; Pacheco Pages, A; Stradling, A

    2013-01-01

    In the LHC operations era, analysis of the multi-petabyte ATLAS data sample by globally distributed physicists is a challenging task. To attain the required scale the ATLAS Computing Model was designed around the concept of grid computing, realized in the Worldwide LHC Computing Grid (WLCG), the largest distributed computational resource existing in the sciences. The ATLAS experiment currently stores over 140 PB of data and runs about 140,000 concurrent jobs continuously at WLCG sites. During the first run of the LHC, the ATLAS Distributed Analysis (DA) service has operated stably and scaled as planned. More than 1600 users submitted jobs in 2012, with 2 million or more analysis jobs per week, peaking at about a million jobs per day. The system dynamically distributes popular data to expedite processing and maximally utilize resources. The reliability of the DA service is high but steadily improving; grid sites are continually validated against a set of standard tests, and a dedicated team of expert shifters ...

  4. The ATLAS Distributed Analysis System

    CERN Document Server

    Legger, F; The ATLAS collaboration

    2014-01-01

    In the LHC operations era, analysis of the multi-petabyte ATLAS data sample by globally distributed physicists is a challenging task. To attain the required scale the ATLAS Computing Model was designed around the concept of grid computing, realized in the Worldwide LHC Computing Grid (WLCG), the largest distributed computational resource existing in the sciences. The ATLAS experiment currently stores over 140 PB of data and runs about 140,000 concurrent jobs continuously at WLCG sites. During the first run of the LHC, the ATLAS Distributed Analysis (DA) service has operated stably and scaled as planned. More than 1600 users submitted jobs in 2012, with 2 million or more analysis jobs per week, peaking at about a million jobs per day. The system dynamically distributes popular data to expedite processing and maximally utilize resources. The reliability of the DA service is high but steadily improving; grid sites are continually validated against a set of standard tests, and a dedicated team of expert shifters ...

  5. Comparison between nutritional risk tools and parameters derived from bioelectrical impedance analysis with subjective global assessment.

    Science.gov (United States)

    Meireles, Marion Schneider; Wazlawik, Elisabeth; Bastos, João Luiz; Garcia, Monique Ferreira

    2012-10-01

    Nutritional risk and malnutrition are highly prevalent among hospitalized patients. As a result, several methods have been developed to produce an adequate nutritional diagnosis. We aimed to assess the relationship between nutritional risk tools and parameters derived from bioelectrical impedance analysis with a Subjective Global Assessment (SGA). A cross-sectional study was conducted from April to September 2010. The study included 124 patients admitted to the Surgical Clinic I, University Hospital, Federal University of Santa Catarina, Florianópolis, Brazil, to undergo elective surgery. We utilized SGA and Nutritional Risk Screening 2002 (NRS 2002), Nutritional Risk Index (NRI), Fat-Free Mass Index (FFMI), Fat Mass Index (FMI), body cell mass as a percentage of the total weight (%BCM), and standardized phase angle (SPA). The agreement was tested by κ coefficient, while bivariate associations were tested by Mann-Whitney U test. Prevalence of nutritional risk by NRS 2002 and NRI or malnutrition by SGA, FFMI, FMI, %BCM, and SPA was 19.3%, 69.5%, 35.5%, 12.9%, 8.1%, 46.8%, and 4.8%, respectively. The best agreement was between SGA and NRS 2002 (κ=.490), possibly because they constitute similar instruments. Patients identified as malnourished by SGA (B+C) showed considerably lower values of FFMI, FMI, BCM, and SPA. The results suggest that the NRS 2002 and parameters derived from bioelectrical impedance analysis identify patients with impaired nutritional status. Copyright © 2012 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  6. On dynamic analysis of variable thickness disks and complex rotors subjected to thermal and mechanical prestresses

    Science.gov (United States)

    Entezari, A.; Filippi, M.; Carrera, E.

    2017-09-01

    This paper is focused on the analysis of complex rotating structures subjected to plausible operating conditions. Effects of the temperature gradient and the centrifugal stiffening contribution have been evaluated. In particular, the analyses have been performed considering disks with constant and variable thicknesses, which have been assumed either clamped at the bore or supported by a deformable shaft. The prestress contributions have been obtained through the integration of the three-dimensional stress state, which is generated by centrifugal and thermal loads, multiplied by the non-linear terms of the strain field. The weak form of the governing equations has been solved using the Finite Element method. High-fidelity one-dimensional elements have been developed according to the Carrera Unified Formulation. The comparisons between the current results and those obtained from solid finite element solutions have demonstrated that the proposed methodology can represent a valuable alternative to the three-dimensional modelling technique by ensuring a comparable accuracy with a lower computational effort.

  7. Finite Element Analysis of Aluminum Honeycombs Subjected to Dynamic Indentation and Compression Loads

    Directory of Open Access Journals (Sweden)

    A.S.M. Ayman Ashab

    2016-03-01

    Full Text Available The mechanical behavior of aluminum hexagonal honeycombs subjected to out-of-plane dynamic indentation and compression loads has been investigated numerically using ANSYS/LS-DYNA in this paper. The finite element (FE models have been verified by previous experimental results in terms of deformation pattern, stress-strain curve, and energy dissipation. The verified FE models have then been used in comprehensive numerical analysis of different aluminum honeycombs. Plateau stress, σpl, and dissipated energy (EI for indentation and EC for compression have been calculated at different strain rates ranging from 102 to 104 s−1. The effects of strain rate and t/l ratio on the plateau stress, dissipated energy, and tearing energy have been discussed. An empirical formula is proposed to describe the relationship between the tearing energy per unit fracture area, relative density, and strain rate for honeycombs. Moreover, it has been found that a generic formula can be used to describe the relationship between tearing energy per unit fracture area and relative density for both aluminum honeycombs and foams.

  8. Thermal analysis of GFRP-reinforced continuous concrete decks subjected to top fire

    Science.gov (United States)

    Hawileh, Rami A.; Rasheed, Hayder A.

    2017-09-01

    This paper presents a numerical study that investigates the behavior of continuous concrete decks doubly reinforced with top and bottom glass fiber reinforced polymer (GFRP) bars subjected to top surface fire. A finite element (FE) model is developed and a detailed transient thermal analysis is performed on a continuous concrete bridge deck under the effect of various fire curves. A parametric study is performed to examine the top cover thickness and the critical fire exposure curve needed to fully degrade the top GFRP bars while achieving certain fire ratings for the deck considered. Accordingly, design tables are prepared for each fire curve to guide the engineer to properly size the top concrete cover and maintain the temperature in the GFRP bars below critical design values in order to control the full top GFRP degradation. It is notable to indicate that degradation of top GFRP bars do not pose a collapse hazard but rather a serviceability concern since cracks in the negative moment region widen resulting in simply supported spans.

  9. Oral reading fluency analysis in patients with Alzheimer disease and asymptomatic control subjects.

    Science.gov (United States)

    Martínez-Sánchez, F; Meilán, J J G; García-Sevilla, J; Carro, J; Arana, J M

    2013-01-01

    Many studies highlight that an impaired ability to communicate is one of the key clinical features of Alzheimer disease (AD). To study temporal organisation of speech in an oral reading task in patients with AD and in matched healthy controls using a semi-automatic method, and evaluate that method's ability to discriminate between the 2 groups. A test with an oral reading task was administered to 70 subjects, comprising 35 AD patients and 35 controls. Before speech samples were recorded, participants completed a battery of neuropsychological tests. There were no differences between groups with regard to age, sex, or educational level. All of the study variables showed impairment in the AD group. According to the results, AD patients' oral reading was marked by reduced speech and articulation rates, low effectiveness of phonation time, and increases in the number and proportion of pauses. Signal processing algorithms applied to reading fluency recordings were shown to be capable of differentiating between AD patients and controls with an accuracy of 80% (specificity 74.2%, sensitivity 77.1%) based on speech rate. Analysis of oral reading fluency may be useful as a tool for the objective study and quantification of speech deficits in AD. Copyright © 2012 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  10. Differences between surface EMG in male and female subjects evidenced by automatic analysis.

    Science.gov (United States)

    Cioni, R; Giannini, F; Paradiso, C; Battistini, N; Denoth, F; Navona, C; Starita, A

    1988-10-01

    40 healthy volunteers (20 males and 20 females) have been studied by an automatic analysis of their surface EMG. The power density spectrum (PDS) of the electromyographic signal, derived from the tibialis anterior muscle, was used to evaluate the RMS values of the EMG developed during maximal voluntary (Vc) and evoked (Vm) contractions. The ratios between Vc, calculated over each of 5 frequency bands (5-15, 20-40, 45-70, 75-110, 115-160 Hz), and the total Vc have also been calculated. No significant differences emerge in the Vm values for males and females, whereas the Vc values for female subjects are found to be significantly reduced (P less than 0.001) with respect to the corresponding values for males. Significant differences have also been found concerning the percentage distribution of power in the above mentioned frequency bands for men and women (P less than 0.001). It can thus, be hypothesized that there are two different modalities of motor unit recruitment and that different sociological and cultural traditions may be more important in producing these differences than sexually determined physiological differences.

  11. Analysis of the strain induced martensitic transformation in austenitic steel subjected to dynamic perforation

    Directory of Open Access Journals (Sweden)

    Zaera R.

    2012-08-01

    Full Text Available An experimental and numerical analysis on the martensitic transformation in AISI 304 steel sheets subjected to perforation by conical and hemispherical projectiles is reported. Two target thicknesses are considered, 0.5 and 1.0 mm, and impact velocities range from 35 to 200 m/s. The perforation mechanisms are identified and the effect of the projectile nose-shape on the ability of the target for energy absorption is evaluated. Martensite has been detected in all the impacted samples and the role played by the projectile nose-shape on the transformation is highlighted. A 3D model implemented in ABAQUS/Explicit allowed to simulate the perforation tests. The material is defined through a constitutive description developed by the authors to describe the strain induced martensitic transformation taking place in metastable austenitic steels at high strain rates. The numerical results are compared with the experimental evidence and satisfactory matching is obtained. The numerical model succeeds in describing the perforation mechanisms associated to each projectile-target configuration analysed.

  12. Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis.

    Science.gov (United States)

    Shi, Xiuqin; Xue, Wenhua; Liang, Shuhong; Zhao, Jie; Zhang, Xiaojian

    2016-12-28

    According to previous meta-analyses, coffee consumption reduces the risk of type 2 diabetes mellitus. However, the underlying mechanism remains unknown. Whether caffeine, the key ingredient in coffee, has a beneficial effect on the glycemic homeostasis and the anti-diabetic effect is particularly controversial. The aim of this study was to summarize the effect of acute caffeine ingestion on insulin sensitivity in healthy men. A comprehensive literature search for papers published before April 2016 was conducted in EMBASE, PubMed, and Cochrane Library databases. Randomized controlled trials (RCTs) that investigated the effect of caffeine on insulin sensitivity in healthy humans without diabetes were included. A random effects meta-analysis was conducted using Review Manager 5.3. The search yielded 7 RCTs in which caffeine intake was the single variant. Compared with placebo, caffeine intake significantly decreased the insulin sensitivity index, with a standardized mean difference of -2.06 (95% confidence interval -2.67 to -1.44, I2 = 49%, P for heterogeneity = 0.06). Acute caffeine ingestion reduces insulin sensitivity in healthy subjects. Thus, in the short term, caffeine might shift glycemic homeostasis toward hyperglycemia. Long-term trials investigating the role of caffeine in the anti-diabetic effect of coffee are needed.

  13. A corpus-based lexical analysis of subject-specific university textbooks for English majors

    Directory of Open Access Journals (Sweden)

    Konul Hajiyeva

    2015-01-01

    Full Text Available This study is a corpus-based lexical analysis of subject-specific university textbooks which purports to explore lexical text coverage and frequency distribution of words from the Academic Word List and the British National Corpus frequency-based word families. For this study a 508,802-word corpus was created, the findings of which reflect that the Academic Word List word families constitute only a small coverage (6.5% of the words in the entire corpus, whereas the first two thousand high-frequency word families give the coverage of 88.92%. In terms of the text coverage, the results reveal that if 98% coverage of a text is needed for unassisted comprehension, then a vocabulary size of 9000 word families is required. The results also substantiate the claims that the Academic Word List is not as general an academic vocabulary as it was initially intended to be and, more importantly, supports the assumption that students need a more restricted core academic vocabulary. It is therefore argued that 127 academic word families which are relatively frequent in the overall university textbook corpus can be used as a part of the university word list for second-year English majors who have to read and comprehend university textbooks.

  14. Thermal analysis of GFRP-reinforced continuous concrete decks subjected to top fire

    Science.gov (United States)

    Hawileh, Rami A.; Rasheed, Hayder A.

    2017-12-01

    This paper presents a numerical study that investigates the behavior of continuous concrete decks doubly reinforced with top and bottom glass fiber reinforced polymer (GFRP) bars subjected to top surface fire. A finite element (FE) model is developed and a detailed transient thermal analysis is performed on a continuous concrete bridge deck under the effect of various fire curves. A parametric study is performed to examine the top cover thickness and the critical fire exposure curve needed to fully degrade the top GFRP bars while achieving certain fire ratings for the deck considered. Accordingly, design tables are prepared for each fire curve to guide the engineer to properly size the top concrete cover and maintain the temperature in the GFRP bars below critical design values in order to control the full top GFRP degradation. It is notable to indicate that degradation of top GFRP bars do not pose a collapse hazard but rather a serviceability concern since cracks in the negative moment region widen resulting in simply supported spans.

  15. Philosophic-educational intelligence analysis as a subject of marketing Management

    Directory of Open Access Journals (Sweden)

    N. V. Litvinenko

    2014-12-01

    Full Text Available The highest value for the philosophical problems of education should consider introducing within the philosophical foundations of marketing management methodology for systematic consideration of education as a social subject­object process, which is based on needs. Philosophy of Education in the face of marketing philosophy and management philosophy got a good theoretical and methodological framework for the synthesis of market interpretations educational development and the development of fundamental issues about the role of education in post­industrial society as a generator of social development. The main aspect of marketing regulation of educational realm of the public institutions today is to improve the quality of education as a basis for the growth of human potential. In determining the directions of philosophical and educational analysis of marketing management in education must be taken into account and general methodological integrative relations philosophy, philosophy of education, philosophy, management and marketing philosophy and substantive features of marketing management, by socio­cultural specificity of the educational sphere. Paradigmatic status of philosophy of education in relation to marketing management in education programming it appears in forms of social activities are implemented through educational transformation in determining the paradigmatic foundations of strategic management of education, and many other determining influence.

  16. Safety analysis of nuclear containment vessels subjected to strong earthquakes and subsequent tsunamis

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Feng; Li, Hong Zhi [Dept. Structural Engineering, Tongji University, Shanghai (China)

    2017-08-15

    Nuclear power plants under expansion and under construction in China are mostly located in coastal areas, which means they are at risk of suffering strong earthquakes and subsequent tsunamis. This paper presents a safety analysis for a new reinforced concrete containment vessel in such events. A finite element method-based model was built, verified, and first used to understand the seismic performance of the containment vessel under earthquakes with increased intensities. Then, the model was used to assess the safety performance of the containment vessel subject to an earthquake with peak ground acceleration (PGA) of 0.56g and subsequent tsunamis with increased inundation depths, similar to the 2011 Great East earthquake and tsunami in Japan. Results indicated that the containment vessel reached Limit State I (concrete cracking) and Limit State II (concrete crushing) when the PGAs were in a range of 0.8–1.1g and 1.2–1.7g, respectively. The containment vessel reached Limit State I with a tsunami inundation depth of 10 m after suffering an earthquake with a PGA of 0.56g. A site-specific hazard assessment was conducted to consider the likelihood of tsunami sources.

  17. Systems Analysis of Thrombus Formation.

    Science.gov (United States)

    Diamond, Scott L

    2016-04-29

    The systems analysis of thrombosis seeks to quantitatively predict blood function in a given vascular wall and hemodynamic context. Relevant to both venous and arterial thrombosis, a Blood Systems Biology approach should provide metrics for rate and molecular mechanisms of clot growth, thrombotic risk, pharmacological response, and utility of new therapeutic targets. As a rapidly created multicellular aggregate with a polymerized fibrin matrix, blood clots result from hundreds of unique reactions within and around platelets propagating in space and time under hemodynamic conditions. Coronary artery thrombosis is dominated by atherosclerotic plaque rupture, complex pulsatile flows through stenotic regions producing high wall shear stresses, and plaque-derived tissue factor driving thrombin production. In contrast, venous thrombosis is dominated by stasis or depressed flows, endothelial inflammation, white blood cell-derived tissue factor, and ample red blood cell incorporation. By imaging vessels, patient-specific assessment using computational fluid dynamics provides an estimate of local hemodynamics and fractional flow reserve. High-dimensional ex vivo phenotyping of platelet and coagulation can now power multiscale computer simulations at the subcellular to cellular to whole vessel scale of heart attacks or strokes. In addition, an integrated systems biology approach can rank safety and efficacy metrics of various pharmacological interventions or clinical trial designs. © 2016 American Heart Association, Inc.

  18. Tank waste remediation system (TWRS) mission analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rieck, R.H.

    1996-10-03

    The Tank Waste Remediation System Mission Analysis provides program level requirements and identifies system boundaries and interfaces. Measures of success appropriate to program level accomplishments are also identified.

  19. Citation analysis with medical subject Headings (MeSH) using the Web of Knowledge: A new routine

    NARCIS (Netherlands)

    Leydesdorff, L.; Opthof, T.

    2013-01-01

    Citation analysis of documents retrieved from the Medline database (at the Web of Knowledge) has been possible only on a case-by-case basis. A technique is presented here for citation analysis in batch mode using both Medical Subject Headings (MeSH) at the Web of Knowledge and the Science Citation

  20. An operational system for subject switching between controlled vocabularies: A computational linguistics approach

    Science.gov (United States)

    Silvester, J. P.; Newton, R.; Klingbiel, P. H.

    1984-01-01

    The NASA Lexical Dictionary (NLD), a system that automatically translates input subject terms to those of NASA, was developed in four phases. Phase One provided Phrase Matching, a context sensitive word-matching process that matches input phrase words with any NASA Thesaurus posting (i.e., index) term or Use reference. Other Use references have been added to enable the matching of synonyms, variant spellings, and some words with the same root. Phase Two provided the capability of translating any individual DTIC term to one or more NASA terms having the same meaning. Phase Three provided NASA terms having equivalent concepts for two or more DTIC terms, i.e., coordinations of DTIC terms. Phase Four was concerned with indexer feedback and maintenance. Although the original NLD construction involved much manual data entry, ways were found to automate nearly all but the intellectual decision-making processes. In addition to finding improved ways to construct a lexical dictionary, applications for the NLD have been found and are being developed.

  1. Absorption spectrum of a two-level system subjected to a periodic pulse sequence

    Science.gov (United States)

    Fotso, H. F.; Dobrovitski, V. V.

    2017-06-01

    We investigate how the quantum control of a two-level system (TLS) coupled to photons can modify and tune the TLS's photon absorption spectrum. Tuning and controlling the emission and the absorption are of great interest, e.g., for the development of efficient interfaces between stationary and flying qubits in modern architectures for quantum computation and quantum communication. We consider periodic pulse control, where the TLS is subjected to a periodic sequence of the near-resonant Rabi driving pulses, each pulse implementing a 180∘ rotation. For small interpulse delays, the absorption spectrum features a pronounced peak of stimulated emission at the pulse frequency, similar satellite peaks with smaller spectral weights, and the net absorption peaks on the sides. As long as the detuning between the carrier frequency of the driving and the TLS transition frequency remains moderate, this spectral shape shows little change. Therefore, the pulse control allows shifting the absorption peak to a desired position and locks the overall absorption spectrum to the carrier frequency of the driving pulses. A detailed description of the spectrum and its evolution as a function time, the interpulse spacing, and the detuning is presented.

  2. Stochastic resonance in a tumor-immune system subject to bounded noises and time delay

    Science.gov (United States)

    Guo, Wei; Mei, Dong-Cheng

    2014-12-01

    Immunotherapy is one of the most recent approaches in cancer therapy. A mathematical model of tumor-immune interaction, subject to a periodic immunotherapy treatment (imitated by a periodic signal), correlative and bounded stochastic fluctuations and time delays, is investigated by numerical simulations for its signal power amplification (SPA). Within the tailored parameter regime, the synchronous response of tumor growth to the immunotherapy, stochastic resonance (SR), versus both the noises and delays is obtained. The details are as follows (i) the peak values of SPA versus the noise intensity (A) in the proliferation term of tumor cells decrease as the frequency of periodic signal increases, i.e. an increase of the frequency restrains the SR; (ii) an increase of the amplitude of periodic signal restrains the SR versus A, but boosts up the SR versus the noise intensity B in the immune term; (iii) there is an optimum cross-correlated degree between the two bounded noises, at which the system exhibits the strongest SR versus the delay time τα(the reaction time of tumor cell population to their surrounding environment constraints); (iv) upon increasing the delay time τα, double SR versus the delay time τβ (the time taken by both the tumor antigen identification and tumor-stimulated proliferation of effectors) emerges. These results may be helpful for an immunotherapy treatment for the sufferer.

  3. Mapping of medical acronyms and initialisms to Medical Subject Headings (MeSH) across selected systems.

    Science.gov (United States)

    Shultz, Mary

    2006-10-01

    Given the common use of acronyms and initialisms in the health sciences, searchers may be entering these abbreviated terms rather than full phrases when searching online systems. The purpose of this study is to evaluate how various MEDLINE Medical Subject Headings (MeSH) interfaces map acronyms and initialisms to the MeSH vocabulary. The interfaces used in this study were: the PubMed MeSH database, the PubMed Automatic Term Mapping feature, the NLM Gateway Term Finder, and Ovid MEDLINE. Acronyms and initialisms were randomly selected from 2 print sources. The test data set included 415 randomly selected acronyms and initialisms whose related meanings were found to be MeSH terms. Each acronym and initialism was entered into each MEDLINE MeSH interface to determine if it mapped to the corresponding MeSH term. Separately, 46 commonly used acronyms and initialisms were tested. While performance differed widely, the success rates were low across all interfaces for the randomly selected terms. The common acronyms and initialisms tested at higher success rates across the interfaces, but the differences between the interfaces remained. Online interfaces do not always map medical acronyms and initialisms to their corresponding MeSH phrases. This may lead to inaccurate results and missed information if acronyms and initialisms are used in search strategies.

  4. Evaluation of a smartphone-based assessment system in subjects with chronic ankle instability.

    Science.gov (United States)

    Chiu, Ya-Lan; Tsai, Yi-Ju; Lin, Chueh-Ho; Hou, You-Ruei; Sung, Wen-Hsu

    2017-02-01

    Ankle sprain is the most common sports-related injury, and approximately 80% of patients studied suffered recurrent sprains. These repeated ankle injuries could cause chronic ankle instability, a decrease in sports performance, and a decrease in postural control ability. At the present time, smartphones have become very popular and powerful devices, and smartphone applications (apps) that have been shown to have good validity have been designed to measure human body motion. However, the app focusing on ankle function assessment and rehabilitation is still not widely used and has very limited functions. The purpose of this study is to evaluate the feasibility of smartphone-based systems in the assessment of postural control ability for patients with chronic ankle instability. Fifteen physically active adults (6 male, 9 female; aged = 23.4 ± 5.28 years; height = 167.13 ± 7.3 cm; weight = 62.06 ± 10.82 kg; BMI = 22.08 ± 2.57 kg/ m2) were recruited, and these participants had at least one leg that was evaluated as scoring lower than 27 points according to the Cumberland Ankle Instability Tool (CAIT). The smartphone used in the study was ASUS Zenfone 2, and an app developed using MIT App Inventor was used to record built-in accelerometer data during the assessment process. Subjects were asked to perform single leg stance for 20 s in eyes-open and eyes-closed conditions with each leg. The smartphone was fixed in an upright position on the middle of the shin, using an exercise armband, with the screen facing forward. The average of recorded acceleration data was used to represent the postural control performance, and higher values indicated more instability. Data were analyzed with a paired t-test with SPSS 17.0, and the statistical significance was set as alpha smartphone software can be used to discriminate between the different performances of the healthier leg and injured leg, and also between eyes-open and eyes

  5. Characteristics of Vocal Fold Vibrations in Vocally Healthy Subjects: Analysis with Multi-Line Kymography

    Science.gov (United States)

    Yamauchi, Akihito; Imagawa, Hiroshi; Sakakibara, Ken-Ichi; Yokonishi, Hisayuki; Nito, Takaharu; Yamasoba, Tatsuya; Tayama, Niro

    2014-01-01

    Purpose: In this study, the authors aimed to analyze longitudinal data from high-speed digital images in normative subjects using multi-line kymography. Method: Vocally healthy subjects were divided into young (9 men and 17 women; M[subscript age] = 27 years) and older groups (8 men and 12 women; M[subscript age] = 73 years). From high-speed…

  6. Analysis of Subjects' Vulnerability in a Touch Screen Game Using Behavioral Metrics.

    Science.gov (United States)

    Parsinejad, Payam; Sipahi, Rifat

    2017-12-01

    In this article, we report results on an experimental study conducted with volunteer subjects playing a touch-screen game with two unique difficulty levels. Subjects have knowledge about the rules of both game levels, but only sufficient playing experience with the easy level of the game, making them vulnerable with the difficult level. Several behavioral metrics associated with subjects' playing the game are studied in order to assess subjects' mental-workload changes induced by their vulnerability. Specifically, these metrics are calculated based on subjects' finger kinematics and decision making times, which are then compared with baseline metrics, namely, performance metrics pertaining to how well the game is played and a physiological metric called pnn50 extracted from heart rate measurements. In balanced experiments and supported by comparisons with baseline metrics, it is found that some of the studied behavioral metrics have the potential to be used to infer subjects' mental workload changes through different levels of the game. These metrics, which are decoupled from task specifics, relate to subjects' ability to develop strategies to play the game, and hence have the advantage of offering insight into subjects' task-load and vulnerability assessment across various experimental settings.

  7. Morphometric connectivity analysis to distinguish normal, mild cognitive impaired, and Alzheimer subjects based on brain MRI

    DEFF Research Database (Denmark)

    Erleben, Lene Lillemark; Sørensen, Lauge; Mysling, Peter

    2013-01-01

    This work investigates a novel way of looking at the regions in the brain and their relationship as possible markers to classify normal control (NC), mild cognitive impaired (MCI), and Alzheimer Disease (AD) subjects. MRI scans from a subset of 101 subjects from the ADNI study at baseline was used...

  8. First Lapses to Smoking: Within-Subjects Analysis of Real-Time Reports.

    Science.gov (United States)

    Shiffman, Saul; And Others

    1996-01-01

    Studies of smoking relapse and temptation have relied on retrospective recall and confounded between- and within-subject variability. Real-time data on temptations and lapses to smoke were gathered using palm-top computers in 108 ex-smokers. Made within-subject comparisons of initial lapse, a temptation episode, and base rate data obtained through…

  9. Assessing the efficiency and the criticality of the elements belonging to a complex territorial system subject to natural hazards

    Directory of Open Access Journals (Sweden)

    R. Minciardi

    2006-01-01

    Full Text Available The effects of natural hazards can be mitigated by the use of proper 'pre-event' interventions on 'key' elements of the territory, that is on elements that are mostly vulnerable to a given catastrophic scenario and whose loss of functionality can cause damages on people, property and environment. In this respect, methodologies and tools should be studied to support decision makers in the analysis of a territory, in order to point out such elements. In this work, vulnerability is taken into account under two aspects: 'physical vulnerability', which measures the propensity of a territorial element to suffer damage when subject to an external stress corresponding to the occurrence of a natural phenomenon; 'functional vulnerability', which measures the propensity of a territorial element to suffer loss in functionality, even when that is caused by the loss of functionality of other territorial elements. In the proposed modeling approach, vulnerability is represented through the use of a graph-based formalization. A territorial system is represented as a complex set of elements or sub-systems. Such elements have differentiated and dedicated functions, and they may be functionally interconnected among them. In addition, vulnerability is defined through the use of two different variables, namely the criticality and the efficiency. Focusing the attention on the temporal phases corresponding to the occurrence of a calamitous event, the first one measures the service demand of an element, whereas the efficiency is a measure of the service that can be offered by such an element. The approach presented is largely independent from the natural risk considered. Besides, the tools introduced for the vulnerability analysis of the territorial system can also be used to formalize decision problems relevant to the location of the available resources for emergency management. A specific case study pertaining to the hydrological risk in the Val di Vara area (Italy is

  10. Wavelet coherence analysis of spontaneous oscillations in cerebral tissue oxyhemoglobin concentrations and arterial blood pressure in elderly subjects.

    Science.gov (United States)

    Cui, Ruofei; Zhang, Ming; Li, Zengyong; Xin, Qing; Lu, Liqian; Zhou, Weiei; Han, Qingyu; Gao, Yuanjin

    2014-05-01

    This study aims to assess the relationship between spontaneous oscillations in changes in cerebral tissue oxyhemoglobin concentrations (Delta [HbO2]) and arterial blood pressure (ABP) signals in healthy elderly subjects during the resting state using wavelet coherence analysis. Continuous recordings of near-infrared spectroscopy (NIRS) and ABP signals were obtained from simultaneous measurements in 33 healthy elderly subjects (age: 70.7±7.9 years) and 27 young subjects (age: 25.2±3.7 years) during the resting state. The coherence between Delta [HbO2] and ABP oscillations in six frequency intervals (I, 0.4-2 Hz; II, 0.15-0.4 Hz; III, 0.05-0.15 Hz; IV, 0.02-0.05 Hz, V, 0.005-0.0095 Hz and VI, 0.005-0.0095 Hz) was analyzed using wavelet coherence analysis. In elderly subjects, the Delta [HbO2] and ABP oscillations were significantly wavelet coherent in interval I, and wavelet phase coherent in intervals I, II and IV. The wavelet coherence in interval I was significantly higher (p=0.040), in elderly subjects than in young subjects whereas that in interval V significantly lower (p=0.015). In addition, the wavelet phase coherence in interval IV was significantly higher in elderly subjects than in young subjects (p=0.028). The difference in the wavelet coherence of the elderly subjects and the young subjects indicates an altered cerebral autoregulation caused by aging. This study provides new insight into the dynamics of Delta [HbO2] and ABP oscillations and may be useful in identifying the risk for dynamic cerebral autoregulation processes. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Non-linear modal analysis of structural components subjected to unilateral constraints

    Science.gov (United States)

    Attar, M.; Karrech, A.; Regenauer-Lieb, K.

    2017-02-01

    In this paper, we present a detailed numerical study of the non-linear dynamics in structural components under unilateral contact constraints. Here, the unilateral term characterises the constitutive law of the restoring force in the constraints as they only sustain elastic reactions in one direction, either compressive or tensile. Thus, the non-differentiability of the contact law at the discontinuity point is the only source of non-linearity. In our approach, the discrete lattice method (DLM) is used to treat the continuous system as a piecewise linear model. Thus, the trajectory of each node in the discrete model would be a sequence of smooth solutions with the switching times between them. The application of the one-step integration scheme allows us to detect the occurrence of contact (i.e. the instants that the lattice nodes cross the discontinuity boundary) and consequently update the active constraints. We also consider embedding the bisection algorithm into the time integration procedure to localise the instants at which the nodes cross the boundary and minimise the accumulative error. Subsequently, the resulting unconditionally stable integration scheme is utilised as the modelling tool in combination with the shooting technique to perform a novel non-smooth modal analysis. In analogy with the smooth non-linear systems, the evolution of non-smooth periodic motions is presented in the frequency-stiffness plots. We apply our method to obtain non-linear normal modes (NNMs) for a number of representative problems, including a bar-obstacle system, a beam-substrate system and a granular chain with tensionless interactions. These numerical examples demonstrate the efficiency of the solution procedure to trace the family of energy-independent non-linear modes across the range of contact stiffnesses. Moreover, the stability analysis of the modes on the plot backbone reveal that they may become unstable due to the interaction with the higher modes or bifurcation of

  12. Markovian queue optimisation analysis with an unreliable server subject to working breakdowns and impatient customers

    Science.gov (United States)

    Liou, Cheng-Dar

    2015-09-01

    This study investigates an infinite capacity Markovian queue with a single unreliable service station, in which the customers may balk (do not enter) and renege (leave the queue after entering). The unreliable service station can be working breakdowns even if no customers are in the system. The matrix-analytic method is used to compute the steady-state probabilities for the number of customers, rate matrix and stability condition in the system. The single-objective model for cost and bi-objective model for cost and expected waiting time are derived in the system to fit in with practical applications. The particle swarm optimisation algorithm is implemented to find the optimal combinations of parameters in the pursuit of minimum cost. Two different approaches are used to identify the Pareto optimal set and compared: the epsilon-constraint method and non-dominate sorting genetic algorithm. Compared results allow using the traditional optimisation approach epsilon-constraint method, which is computationally faster and permits a direct sensitivity analysis of the solution under constraint or parameter perturbation. The Pareto front and non-dominated solutions set are obtained and illustrated. The decision makers can use these to improve their decision-making quality.

  13. Power electronic systems Walsh analysis with Matlab

    CERN Document Server

    Deb, Anish

    2014-01-01

    A Totally Different Outlook on Power Electronic System AnalysisPower Electronic Systems: Walsh Analysis with MATLAB® builds a case for Walsh analysis as a powerful tool in the study of power electronic systems. It considers the application of Walsh functions in analyzing power electronic systems, and the advantages offered by Walsh domain analysis of power electronic systems. Solves Power Electronic Systems in an Unconventional WayThis book successfully integrates power electronics as well as systems and control. Incorporating a complete orthonormal function set very much unlike the sine-cosin

  14. Paranoid Ideation and Violence: Meta-analysis of Individual Subject Data of 7 Population Surveys

    Science.gov (United States)

    Coid, Jeremy W.; Ullrich, Simone; Bebbington, Paul; Fazel, Seena; Keers, Robert

    2016-01-01

    There is controversy whether associations between psychosis and violence are due to coexisting substance misuse and factors increasing risk in nonpsychotic persons. Recent studies in clinical samples have implicated independent effects of paranoid delusions. Research findings suggest that individual psychotic-like-experiences on the psychosis continuum in the general population are associated with violence; it remains unclear whether this association is due to psychiatric comorbidity. We pooled data from 7 UK general population surveys (n = 23 444) and conducted a meta-analysis of individual subject data. Further meta-analyses were performed to identify heterogeneity. Main exposure variables: 5 psychotic-like-experiences and a categorical measure of psychosis. Comorbidity was established through standardized self-report instruments. Information was collected on violence, severity, victims. Paranoid ideation was associated with violence (AOR 2.26, 95% CI 1.75–2.91), severity and frequency, even when controlling for effects of other psychotic-like-experiences. Associations were not explained by comorbid conditions, including substance dependence. Psychotic disorder was associated with violence and injury to the perpetrator but associations were explained by paranoid ideation. Individual associations between hypomania, thought insertion, hallucinations, and violence were nonsignificant after adjustments, and significantly associated only when comorbid with antisocial personality disorder. Strange experiences were only associated with intimate partner violence. Paranoid ideation on a psychosis-continuum in the general population was associated with violence. All other associations were explained by comorbidity. Further investigation should determine whether paranoid ideation among persons in the community require preventive interventions, similar to those presenting to mental health services. Nevertheless, risks are considerably increased for psychotic

  15. Prospective analysis of splinting the first carpometacarpal joint: an objective, subjective, and radiographic assessment.

    Science.gov (United States)

    Weiss, S; LaStayo, P; Mills, A; Bramlet, D

    2000-01-01

    Predisposing factors contributing to the development of first carpometacarpal (CMC) osteoarthritis include an inherent laxity or incongruency of this joint, a shallow trapezium saddle, and heavy stresses placed on the joint with pinching and grasping. Splinting is a common mode of conservative treatment for CMC osteoarthritis. This study assessed the objective and subjective responses of patients with CMC osteoarthritis who wore short and long opponens splints, as well as radiographic changes associated with wearing of the splints. The study evaluated 26 hands. Each patient was assigned at random to wear the long or the short splint first. Patients wore the splints for one week. They then documented function in their splints (on 22 activities of daily living) and rated splint satisfaction and pain levels on visual analog scales. One week after application of the first splint, the second splint was applied and worn for one week, and all measures were repeated. On the final visit, tip pinches were evaluated and x-rays were taken to assess subluxation. One-way repeated-measure analysis and paired comparison were used to analyze the pinch, pain, radiographic, and splint-rating measures. Descriptive statistics were used to assess activity-of-daily-living function and splint preference. Both splints appear to reduce subluxation at the first CMC joint in patients with grades 1 and 2 osteoarthritis. The majority of the patients picked the short splint when asked at the end of the study which splint they preferred. The splints do not appear to increase pinch strength or affect pain levels associated with the performance of pinch strength measurements. This study supports anecdotal evidence that patients with CMC osteoarthritis get pain relief with splinting.

  16. Rhinoplasty and facial asymmetry: Analysis of subjective and anthropometric factors in the Caucasian nose

    Directory of Open Access Journals (Sweden)

    Carvalho, Bettina

    2012-01-01

    Full Text Available Introduction: Anthropometric proportions and symmetry are considered determinants of beauty. These parameters have significant importance in facial plastic surgery, particularly in rhinoplasty. As the central organ of the face, the nose is especially important in determining facial symmetry, both through the perception of a crooked nose and through the determination of facial growth. The evaluation of the presence of facial asymmetry has great relevance preoperatively, both for surgical planning and counseling. Aim/Objective: To evaluate and document the presence of facial asymmetry in patients during rhinoplasty planning and to correlate the anthropometric measures with the perception of facial symmetry or asymmetry, assessing whether there is a higher prevalence of facial asymmetry in these patients compared to volunteers without nasal complaints. Methods: This prospective study was performed by comparing photographs of patients with rhinoplasty planning and volunteers (controls, n = 201, and by evaluating of anthropometric measurements taken from a line passing through the center of the face, until tragus, medial canthus, corner side wing margin, and oral commissure of each side, by statistical analysis (Z test and odds ratio. Results: None of the patients or volunteers had completely symmetric values. Subjectively, 59% of patients were perceived as asymmetric, against 54% of volunteers. Objectively, more than 89% of respondents had asymmetrical measures. Patients had greater RLMTr (MidLine Tragus Ratio asymmetry than volunteers, which was statistically significant. Discussion/Conclusion: Facial asymmetries are very common in patients seeking rhinoplasty, and special attention should be paid to these aspects both for surgical planning and for counseling of patients.

  17. Reliability analysis and updating of deteriorating systems with subset simulation

    DEFF Research Database (Denmark)

    Schneider, Ronald; Thöns, Sebastian; Straub, Daniel

    2017-01-01

    An efficient approach to reliability analysis of deteriorating structural systems is presented, which considers stochastic dependence among element deterioration. Information on a deteriorating structure obtained through inspection or monitoring is included in the reliability assessment through B...... is an efficient and robust sampling-based algorithm suitable for such analyses. The approach is demonstrated in two case studies considering a steel frame structure and a Daniels system subjected to high-cycle fatigue....

  18. Is Subjective Social Status a Unique Correlate of Physical Health? A Meta-Analysis.

    Science.gov (United States)

    Cundiff, Jenny M; Matthews, Karen A

    2017-07-20

    Both social stratification (e.g., social rank) as well as economic resources (e.g., income) are thought to contribute to socioeconomic health disparities. It has been proposed that subjective socioeconomic status (an individual's perception of his or her hierarchical rank) provides increased predictive utility for physical health over and above more traditional, well-researched socioeconomic constructs such as education, occupation, and income. PsycINFO and PubMed databases were systematically searched for studies examining the association of subjective socioeconomic status (SES) and physical health adjusting for at least 1 measure of objective SES. The final sample included 31 studies and 99 unique effects. Meta-analyses were performed to: (a) estimate the overlap among subjective and objective indicators of SES and (b) estimate the cumulative association of subjective SES with physical health adjusting for objective SES. Potential moderators such as race and type of health indicator assessed (global self-reports vs. more specific and biologically based indicators) were also examined. Across samples, subjective SES shows moderate overlap with objective indicators of SES, but associations are much stronger in Whites than Blacks. Subjective SES evidenced a unique cumulative association with physical health in adults, above and beyond traditional objective indicators of SES (Z = .07, SE = .01, p Subjective SES may provide unique information relevant to understanding disparities in health, especially self-rated health. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. Validation of subject-specific automated p-FE analysis of the proximal femur.

    Science.gov (United States)

    Trabelsi, Nir; Yosibash, Zohar; Milgrom, Charles

    2009-02-09

    The use of subject-specific finite element (FE) models in clinical practice requires a high level of automation and validation. In Yosibash et al. [2007a. Reliable simulations of the human proximal femur by high-order finite element analysis validated by experimental observations. J. Biomechanics 40, 3688-3699] a novel method for generating high-order finite element (p-FE) models from CT scans was presented and validated by experimental observations on two fresh frozen femurs (harvested from a 30 year old male and 21 year old female). Herein, we substantiate the validation process by enlarging the experimental database (54 year old female femur), improving the method and examine its robustness under different CT scan conditions. A fresh frozen femur of a 54 year old female was scanned under two different environments: in air and immersed in water (dry and wet CT). Thereafter, the proximal femur was quasi-statically loaded in vitro by a 1000N load. The two QCT scans were manipulated to generate p-FE models that mimic the experimental conditions. We compared p-FE displacements and strains of the wet CT model to the dry CT model and to the experimental results. In addition, the material assignment strategy was reinvestigated. The inhomogeneous Young's modulus was represented in the FE model using two different methods, directly extracted from the CT data and using continuous spatial functions as in Yosibash et al. [2007a. Reliable simulations of the human proximal femur by high-order finite element analysis validated by experimental observations. J. Biomechanics 40, 3688-3699]. Excellent agreement between dry and wet FE models was found for both displacements and strains, i.e. the method is insensitive to CT conditions and may be used in vivo. Good agreement was also found between FE results and experimental observations. The spatial functions representing Young's modulus are local and do not influence strains and displacements prediction. Finally, the p-FE results of

  20. Tank waste remediation system mission analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Acree, C.D.

    1998-01-06

    The Tank Waste Remediation System Mission Analysis Report identifies the initial states of the system and the desired final states of the system. The Mission Analysis Report identifies target measures of success appropriate to program-level accomplishments. It also identifies program-level requirements and major system boundaries and interfaces.

  1. PERFORMANCE-RELIABILITY – THE MAIN SUBJECT OF THE BANKING ANALYSIS OF THE CREDITED SOCIETIES

    Directory of Open Access Journals (Sweden)

    AVRAM (BOITOŞ CAMELIA

    2013-12-01

    Full Text Available Since the crediting activity occupies the primary role in any banking institution, the necessity of study and its analysis is required by following some steps both at a microeconomic level and at a macroeconomic one. Going over the theme, which aims at the importance of a thorough study of the clients' reliability for highlighting the existing risks in the banking activity in general, and particularly in the crediting activity, becomes as more interesting as their approach at the level of the member states of the European Union tends towards a common theme. Starting from these premises, we have considered as being extremely important the selection of a research theme which aims at the risks in the crediting activity, emphasizing the analysis of the clients' reliability both in the decision of crediting in order to assume the risk of credit and in determining the financial and banking performances. Being given the complexity of the existing risks in the banking activity in general and particularly of the credit risk, the clients' reliability represents an extremely important field, of research and application, bearing in mind both the actual stage of developing the Romanian banking system and the attempts of its alignment to the requirements imposed by the European Union.

  2. A computational analysis subject to thermophysical aspects of Sisko fluid flow over a cylindrical surface

    Science.gov (United States)

    Awais, M.; Khalil-Ur-Rehman; Malik, M. Y.; Hussain, Arif; Salahuddin, T.

    2017-09-01

    The present analysis is devoted to probing the salient features of the mixed convection and non-linear thermal radiation effects on non-Newtonian Sisko fluid flow over a linearly stretching cylindrical surface. Properties of heat transfer are outlined via variable thermal conductivity and convective boundary conditions. The boundary layer approach is implemented to construct the mathematical model in the form of partial differential equations. Then, the requisite PDEs are transmuted into a complex ordinary differential system by invoking appropriate dimensionless variables. Solution of subsequent ODEs is obtained by utilizing the Runge-Kutta algorithm (fifth order) along with the shooting scheme. The graphical illustrations are presented to interpret the features of the involved pertinent flow parameters on concerning profiles. For a better description of the fluid flow, numerical variations in local skin friction coefficient and local Nusselt number are scrutinized in tables. From thorough analysis, it is inferred that the mixed convection parameter and the curvature parameter increase the velocity while temperature shows a different behavior. Additionally, both momentum and thermal distribution of fluid flow decrease with increasing values of the non-linearity index. Furthermore, variable thermal parameter and heat generation/absorption parameter amplify the temperature significantly. The skin friction is an increasing function of all momentum controlling parameters. The local Nusselt number also shows a similar behavior against heat radiation parameter and variable thermal conductivity parameter while it shows a dual nature for the heat generation/absorption parameter. Finally, the obtained results are validated by comparison with the existing literature and hence the correctness of the analysis is proved.

  3. Sleep quality and obesity in young subjects: a meta-analysis

    OpenAIRE

    Fatima, Y.; Doi, S.A.R.; Mamun, A. A.

    2016-01-01

    To assess the effect of poor sleep quality on Overweight/Obesity (Ow/Ob) in young subjects, and explore if this association is independent of sleep duration. Pubmed, EMBASE, and MEDLINE databases were searched for papers on sleep quality and overweight/obesity, focusing on children, adolescents, and young adults. Studies based on subjects with medical/psychological problems or published in languages other than English were excluded. Quality effects model was used to pool studies for meta-anal...

  4. [Clinical analysis of normal subjects and dizzy patients with postural sway test].

    Science.gov (United States)

    Wen, Yan-hua; Jiang, Zi-Dong; Zhang, Yan; Zhang, Lian-Shan; Gao, Zhi-Qiang

    2008-12-01

    To study the characteristics of the normal subjects with postural sway test and discuss the value of postural sway test in the diagnosis of dizzy patients. Totally 112 normal subjects, 72 patients with peripheral vertigo, and 30 patients with central vertigo were examined using a stabilometer (EAB-100, Anima Co., Japan). Items include patterns, length of locus, envelope area, deflection average center displacement, and romberg rate were recorded and compared. The postural sway was classified into the following five patterns: centripetal, forward and backward, right and left, diffuse, and multicentric. Centripetal pattern was the most prominent figure pattern in the normal subjects, while diffuse pattern was the most prominent figure pattern in the patients with central vertigo. When the normal subjects closed their eyes, age was linearly correlated with the length of locus, envelope area, rectangel area, and unit area path length (P < 0.05). Sex was not correlated to all of these parameters. The length of locus and envelope area in the patient groups were significantly increased when compared with the normal subjects (P < 0.0167). Romberg rate was not significantly different between the patients and the normal subjects. The pattern of postural sway is useful for the diagnosis of vertigo. Age is an important factor that affects the balance function. Sex seems has no influence. Visual input plays an important role in maintaining postural balance. Stabilometer is a useful tool for evaluating balance function, and postural sway test may be a valuable assistant examination.

  5. Up-regulation of the complement system in subcutaneous adipocytes from nonobese, hypertriglyceridemic subjects is associated with adipocyte insulin resistance.

    Science.gov (United States)

    van Greevenbroek, M M J; Ghosh, S; van der Kallen, C J H; Brouwers, M C G J; Schalkwijk, C G; Stehouwer, C D A

    2012-12-01

    Dysfunctional adipose tissue plays an important role in the etiology of the metabolic syndrome, type 2 diabetes, and dyslipidemia. However, the molecular mechanisms underlying adipocyte dysfunction are incompletely understood. The aim of the study was to identify differentially regulated pathways in sc adipocytes of dyslipidemic subjects. Whole-genome expression profiling was conducted on sc adipocytes from a discovery group of nine marginally overweight subjects with familial combined hyperlipidemia (FCHL) and nine controls of comparable body sizes as well as two independent confirmation groups. In this study, FCHL served as a model of familial insulin resistance and dyslipidemia, in the absence of frank obesity. Functional analyses and gene set enrichment analysis using the Kyoto Encyclopedia of Genes and Genomes or a custom pathway database identified the complement system and complement regulators as one of the top up-regulated pathways in FCHL [false discovery rate (FDR) complement expression in FCHL was confirmed in the appropriate confirmation group. Higher complement gene expression was associated with lower adipocyte insulin receptor substrate-1 expression as marker of adipocyte insulin resistance, independent of age, sex, or disease status, and this association was corroborated in the two confirmation groups. Additionally, complement gene expression was associated with triglycerides in the discovery set and with triglycerides and/or waist circumference in the confirmation groups. Complement pathway up-regulation did not appear to be driven by hypertriglyceridemia because a 40% pharmacological reduction in triglycerides did not affect complement expression. These findings point to an up-regulation of a complement-related transcriptome in sc adipocytes under metabolically stressed conditions, even in the absence of overt obesity. Such up-regulation may subsequently influence downstream processes, including macrophage infiltration into adipose tissue and

  6. Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies.

    Science.gov (United States)

    Studerus, Erich; Kometer, Michael; Hasler, Felix; Vollenweider, Franz X

    2011-11-01

    Psilocybin and related hallucinogenic compounds are increasingly used in human research. However, due to limited information about potential subjective side effects, the controlled medical use of these compounds has remained controversial. We therefore analysed acute, short- and long-term subjective effects of psilocybin in healthy humans by pooling raw data from eight double-blind placebo-controlled experimental studies conducted between 1999 and 2008. The analysis included 110 healthy subjects who had received 1-4 oral doses of psilocybin (45-315 µg/kg body weight). Although psilocybin dose-dependently induced profound changes in mood, perception, thought and self-experience, most subjects described the experience as pleasurable, enriching and non-threatening. Acute adverse drug reactions, characterized by strong dysphoria and/or anxiety/panic, occurred only in the two highest dose conditions in a relatively small proportion of subjects. All acute adverse drug reactions were successfully managed by providing interpersonal support and did not need psychopharmacological intervention. Follow-up questionnaires indicated no subsequent drug abuse, persisting perception disorders, prolonged psychosis or other long-term impairment of functioning in any of our subjects. The results suggest that the administration of moderate doses of psilocybin to healthy, high-functioning and well-prepared subjects in the context of a carefully monitored research environment is associated with an acceptable level of risk.

  7. Temporal dynamics of the face familiarity effect: bootstrap analysis of single-subject event-related potential data.

    Science.gov (United States)

    Alonso-Prieto, Esther; Pancaroglu, Raika; Dalrymple, Kirsten A; Handy, Todd; Barton, Jason J S; Oruc, Ipek

    2015-01-01

    Prior event-related potential studies using group statistics within a priori selected time windows have yielded conflicting results about familiarity effects in face processing. Our goal was to evaluate the temporal dynamics of the familiarity effect at all time points at the single-subject level. Ten subjects were shown faces of anonymous people or celebrities. Individual results were analysed using a point-by-point bootstrap analysis. While familiarity effects were less consistent at later epochs, all subjects showed them between 130 and 195 ms in occipitotemporal electrodes. However, the relation between the time course of familiarity effects and the peak latency of the N170 was variable. We concluded that familiarity effects between 130 and 195 ms are robust and can be shown in single subjects. The variability of their relation to the timing of the N170 potential may lead to underestimation of familiarity effects in studies that use group-based statistics.

  8. Electrostatic analysis of nanoelectromechanical systems

    Science.gov (United States)

    Xu, Yang

    We present a multiscale method, seamlessly combining semiclassical, effective-mass Schrodinger (EMS), and tight-binding (TB) theories proposed for electrostatic analysis of silicon nanoelectromechanical systems (NEMS). By using appropriate criteria, we identify the physical models that are accurate in each local region. If the local physical model is semiclassical, the charge density is directly computed by the semiclassical theory. If the local physical model is quantum-mechanical (EMS or TB model), the charge density is calculated by using the theory of local density of states (LDOS). The LDOS is efficiently calculated from Green's function by using Haydock's recursion method where the Green's function is expressed as a continued fraction based on the local Hamiltonian. Once the charge density is determined, a Poisson equation is solved self-consistently to determine the electronic properties. The accuracy and efficiency of the multiscale method are demonstrated by considering several NEMS examples. The multiscale method can be used to compute the effect of surface and interior defects such as vacancies and broken bonds on the performance of microelectromechanical systems (MEMS). By combining multiscale electrostatic analysis with mechanical analysis, we compute the capacitance-voltage and pull-in/pull-out voltages of MEMS switches in the presence of defects in the dielectric oxide layer. Our results indicate that both surface and interior defects can change the pull-in/pull-out voltages significantly. These voltage offsets can lead to an eventual failure of the MEMS switches. The self-consistent TB method is used to investigate carbon nanotube (CNT)-based sensors. We compute the screening effects of semiconducting and metallic single-wall carbon nanotubes (SWNTs) when water molecules and various ions pass through the nanotubes. The trajectories of ions and water molecules are obtained from molecular dynamics (MD) simulations. It is shown that metallic SWNTs have

  9. Adaptive thresholding for reliable topological inference in single subject fMRI analysis.

    Science.gov (United States)

    Gorgolewski, Krzysztof J; Storkey, Amos J; Bastin, Mark E; Pernet, Cyril R

    2012-01-01

    Single subject fMRI has proved to be a useful tool for mapping functional areas in clinical procedures such as tumor resection. Using fMRI data, clinicians assess the risk, plan and execute such procedures based on thresholded statistical maps. However, because current thresholding methods were developed mainly in the context of cognitive neuroscience group studies, most single subject fMRI maps are thresholded manually to satisfy specific criteria related to single subject analyzes. Here, we propose a new adaptive thresholding method which combines Gamma-Gaussian mixture modeling with topological thresholding to improve cluster delineation. In a series of simulations we show that by adapting to the signal and noise properties, the new method performs well in terms of total number of errors but also in terms of the trade-off between false negative and positive cluster error rates. Similarly, simulations show that adaptive thresholding performs better than fixed thresholding in terms of over and underestimation of the true activation border (i.e., higher spatial accuracy). Finally, through simulations and a motor test-retest study on 10 volunteer subjects, we show that adaptive thresholding improves reliability, mainly by accounting for the global signal variance. This in turn increases the likelihood that the true activation pattern can be determined offering an automatic yet flexible way to threshold single subject fMRI maps.

  10. Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

    Directory of Open Access Journals (Sweden)

    van Eijk Kristel R

    2012-11-01

    Full Text Available Abstract Background The predominant model for regulation of gene expression through DNA methylation is an inverse association in which increased methylation results in decreased gene expression levels. However, recent studies suggest that the relationship between genetic variation, DNA methylation and expression is more complex. Results Systems genetic approaches for examining relationships between gene expression and methylation array data were used to find both negative and positive associations between these levels. A weighted correlation network analysis revealed that i both transcriptome and methylome are organized in modules, ii co-expression modules are generally not preserved in the methylation data and vice-versa, and iii highly significant correlations exist between co-expression and co-methylation modules, suggesting the existence of factors that affect expression and methylation of different modules (i.e., trans effects at the level of modules. We observed that methylation probes associated with expression in cis were more likely to be located outside CpG islands, whereas specificity for CpG island shores was present when methylation, associated with expression, was under local genetic control. A structural equation model based analysis found strong support in particular for a traditional causal model in which gene expression is regulated by genetic variation via DNA methylation instead of gene expression affecting DNA methylation levels. Conclusions Our results provide new insights into the complex mechanisms between genetic markers, epigenetic mechanisms and gene expression. We find strong support for the classical model of genetic variants regulating methylation, which in turn regulates gene expression. Moreover we show that, although the methylation and expression modules differ, they are highly correlated.

  11. Dynamic transcriptional signatures and network responses for clinical symptoms in influenza-infected human subjects using systems biology approaches.

    Science.gov (United States)

    Linel, Patrice; Wu, Shuang; Deng, Nan; Wu, Hulin

    2014-10-01

    Recent studies demonstrate that human blood transcriptional signatures may be used to support diagnosis and clinical decisions for acute respiratory viral infections such as influenza. In this article, we propose to use a newly developed systems biology approach for time course gene expression data to identify significant dynamically response genes and dynamic gene network responses to viral infection. We illustrate the methodological pipeline by reanalyzing the time course gene expression data from a study with healthy human subjects challenged by live influenza virus. We observed clear differences in the number of significant dynamic response genes (DRGs) between the symptomatic and asymptomatic subjects and also identified DRG signatures for symptomatic subjects with influenza infection. The 505 common DRGs shared by the symptomatic subjects have high consistency with the signature genes for predicting viral infection identified in previous works. The temporal response patterns and network response features were carefully analyzed and investigated.

  12. Preferences and Beliefs in a Sequential Social Dilemma: A Within-Subjects Analysis

    DEFF Research Database (Denmark)

    Blanco, Mariana; Engelmann, Dirk; Koch, Alexander

    Within-subject data from sequential social dilemma experiments reveal a correlation of first and second-mover decisions for which two channels may be responsible, that our experiment allows to separate: i) a direct, preference-based channel that influences both first- and second-mover decisions; ii......) an indirect channel, where second-mover decisions influence beliefs via a consensus effect, and the first-mover decision is a best response to these beliefs. We find strong evidence for the indirect channel: beliefs about second-mover cooperation are biased toward own second-mover behavior, and most subjects...... best respond to stated beliefs. But when first movers know the true probability of second-mover cooperation, subjects' own second moves still have predictive power regarding their first moves, suggesting that the direct channel also plays a role....

  13. Walking speed of normal subjects and amputees: aspects of validity of gait analysis.

    Science.gov (United States)

    Boonstra, A M; Fidler, V; Eisma, W H

    1993-08-01

    This study investigated some aspects of the validity of walking speed recording in 15 normal subjects, 16 trans-femoral amputees and 8 knee disarticulation amputees. The variability and test-retest reliability of walking speed and the influence of simultaneous recording of EMG and goniometry on comfortable and fast walking speeds were studied. The variability between sessions was mainly determined by the variance within each session. The variance of speed within sessions while walking with fast speed, was higher when walking without equipment than when walking with equipment. The variances of speed within sessions of the normal subjects were higher than those for both amputee groups. The test-retest reliability, expressed by the intra-class correlation coefficient, was good: between 0.83 and 0.98. The speed when walking without equipment was significantly higher both in normal subjects and amputees than the speed when walking with equipment.

  14. Evaluation of Subjective Measurement Systems with Focus on Workmanship Scratches and Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Fitzgerald, Jesse

    2011-02-24

    The presence of workmanship defects at the Kansas City Plant (KCP) is not a new problem nor is it an easy one to remedy. The lack of well defined parameters, subjective evaluations, and operator dependency makes this problem difficult to analyze. At the time of project assignment, workmanship defects comprised approximately 50% of all non-conformance reports for internally produced products. Not all of these non-conformances result in product rejections, thus inferring that inconsistency in evaluations were present. The purpose of this study was to identify a method for evaluating an operator’s ability to properly characterize subjective defects. Since the scope of the project was limited to no funding, scratch depth was selected as the only criteria to evaluate. It was determined that the introduction of a reference standard coupled with a predefined gate-sorting technique approved by the customer can statistically improve an operators ability to perform subjective evaluations.

  15. A Meta-Analysis of Single-Subject Research on Behavioral Momentum to Enhance Success in Students with Autism

    Science.gov (United States)

    Cowan, Richard J.; Abel, Leah; Candel, Lindsay

    2017-01-01

    We conducted a meta-analysis of single-subject research studies investigating the effectiveness of antecedent strategies grounded in behavioral momentum for improving compliance and on-task performance for students with autism. First, we assessed the research rigor of those studies meeting our inclusionary criteria. Next, in order to apply a…

  16. A Comparative Analysis of the Colour Subject between Canada Saskatchewan State and Visual Arts Education Curriculum in Turkey

    Science.gov (United States)

    Dabancal, Meral Per

    2015-01-01

    A deeper analysis of the art education curriculums applied in developed countries and treating specific subjects within these curriculums holds vital importance in allowing the production of alternative solution methods by providing the educators multiple perspectives in the face of problems concerning art education. In present paper colour…

  17. Correlation between two-dimensional video analysis and subjective assessment in evaluating knee control among elite female team handball players

    DEFF Research Database (Denmark)

    Stensrud, Silje; Myklebust, Grethe; Kristianslund, Eirik

    2011-01-01

    . The present study investigated the correlation between a two-dimensional (2D) video analysis and subjective assessment performed by one physiotherapist in evaluating knee control. We also tested the correlation between three simple clinical tests using both methods. A cohort of 186 female elite team handball...

  18. Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects: Implications for Analysis of Late HIV Diagnosis

    NARCIS (Netherlands)

    Sobrino-Vegas, Paz; Pérez-Hoyos, Santiago; Geskus, Ronald; Padilla, Belén; Segura, Ferrán; Rubio, Rafael; del Romero, Jorge; Santos, Jesus; Moreno, Santiago; del Amo, Julia

    2012-01-01

    Objectives. Since subjects may have been diagnosed before cohort entry, analysis of late HIV diagnosis (LD) is usually restricted to the newly diagnosed. We estimate the magnitude and risk factors of LD in a cohort of seroprevalent individuals by imputing seroconversion dates. Methods. Multicenter

  19. Bibliometric Analysis of Anatolia Turizm Araştırmaları Dergisi: An Analysis of Research Subjects and Institutional Collabration through Social Network Analysis

    Directory of Open Access Journals (Sweden)

    Deniz Karagöz

    2014-03-01

    Full Text Available Research subjects and collaboration between universities are important knowledge fields about forms of knowledge networks structures in a scientific community and flow of knowledge traffic. The aims of this study revealed to tourism knowledge network structure and institutional collaboration and examined to the roles of research subjects and collaboration into tourism network structure based on published articles in Anatolia Turizm Araştırmaları Dergisi. The data was collected from refereed articles in Anatolia Turizm Araştırmaları Dergisi between years of 1997-2010. Social Network Analysis is used to define network structure and to examine links between structures. For that purpose, UCINET and Netdraw programs were utilized. At the end of this study, tourism knowledge structure generally has central structure rather than interdisciplinary structure. Management, marketing, economy, education, accounting-finance, health and transportation research subjects are to be linked with each other rather than other research subjects. In this research, institutional collaborations are determined in low degree. In addition important roles are determined of University of Dokuz Eylül, University of Gazi and University of Mersin at institutional collaboration and separation of knowledge to other universities.

  20. Mu opioid mediated discriminative-stimulus effects of tramadol: an individual subjects analysis.

    Science.gov (United States)

    Strickland, Justin C; Rush, Craig R; Stoops, William W

    2015-03-01

    Drug discrimination procedures use dose-dependent generalization, substitution, and pretreatment with selective agonists and antagonists to evaluate receptor systems mediating interoceptive effects of drugs. Despite the extensive use of these techniques in the nonhuman animal literature, few studies have used human participants. Specifically, human studies have not routinely used antagonist administration as a pharmacological tool to elucidate the mechanisms mediating the discriminative stimulus effects of drugs. This study evaluated the discriminative-stimulus effects of tramadol, an atypical analgesic with monoamine and mu opioid activity. Three human participants first learned to discriminate 100 mg tramadol from placebo. A range of tramadol doses (25 to 150 mg) and hydromorphone (4 mg) with and without naltrexone pretreatment (50 mg) were then administered to participants after they acquired the discrimination. Tramadol produced dose-dependent increases in drug-appropriate responding and hydromorphone partially or fully substituted for tramadol in all participants. These effects were attenuated by naltrexone. Individual participant records indicated a relationship between mu opioid activity (i.e., miosis) and drug discrimination performance. Our findings indicate that mu opioid activity may mediate the discriminative-stimulus effects of tramadol in humans. The correspondence of generalization, substitution, and pretreatment findings with the animal literature supports the neuropharmacological specificity of the drug discrimination procedure. © Society for the Experimental Analysis of Behavior.

  1. Systems Analysis and Design: Know Your Audience

    Science.gov (United States)

    Reinicke, Bryan A.

    2012-01-01

    Systems analysis and design (SAD) classes are required in both Information Systems and Accounting programs, but these audiences have very different needs for these skills. This article will review the requirements for SAD within each of these disciplines and compare and contrast the different requirements for teaching systems analysis and design…

  2. Minimum Entropy Active Fault Tolerant Control of the Non-Gaussian Stochastic Distribution System Subjected to Mean Constraint

    Directory of Open Access Journals (Sweden)

    Haokun Jin

    2017-05-01

    Full Text Available Stochastic distribution control (SDC systems are a group of systems where the outputs considered is the measured probability density function (PDF of the system output whilst subjected to a normal crisp input. The purpose of the active fault tolerant control of such systems is to use the fault estimation information and other measured information to make the output PDF still track the given distribution when the objective PDF is known. However, if the target PDF is unavailable, the PDF tracking operation will be impossible. Minimum entropy control of the system output can be considered as an alternative strategy. The mean represents the center location of the stochastic variable, and it is reasonable that the minimum entropy fault tolerant controller can be designed subjected to mean constraint. In this paper, using the rational square-root B-spline model for the shape control of the system output probability density function (PDF, a nonlinear adaptive observer based fault diagnosis algorithm is proposed to diagnose the fault. Through the controller reconfiguration, the system entropy subjected to mean restriction can still be minimized when fault occurs. An illustrative example is utilized to demonstrate the use of the minimum entropy fault tolerant control algorithms.

  3. Subjective study of thermal acceptability of novel enhanced displacement ventilation system and implication of occupants' personal control

    DEFF Research Database (Denmark)

    Sun, Weimeng; Cheong, K.W.D.; Melikov, Arsen Krikor

    2012-01-01

    A novel air distribution principle of cooler air near the floor level being propelled upward via four fans mounted at each corner of a chair was developed to enhance the performance of conventional displacement ventilation (DV) system. Experiments were conducted in a well-controlled climate chamber...... with DV and constant heat load at different supply air temperatures, namely 20, 22, and 24 °C and room air temperatures, 22, 24, and 26 °C. Subjective assessments were carried out with 32 tropically-acclimatized college students who were given the choice to adjust the fan speed. Subjects' thermal comfort...... of 22 and 24 °C when the fans were in operation. It was also found that the Whole Body Thermal Sensation (WBTS) reported by the subjects was correlated with the Local Thermal Sensation (LTS) at the waist, the arms, the calf and the feet when the novel DV system was employed. An expression which allows...

  4. An analysis of subject agreement errors in English: the case of third ...

    African Journals Online (AJOL)

    For the incorrect sentences they were to underline the error and give the correct answer. The main findings of the study were: subject-verb agreement errors are prominent in simple sentence constructions and in complex linguistic environments. The study also found that performance errors appear frequently in simple ...

  5. Hierarchical Linear Modeling Meta-Analysis of Single-Subject Design Research

    Science.gov (United States)

    Gage, Nicholas A.; Lewis, Timothy J.

    2014-01-01

    The identification of evidence-based practices continues to provoke issues of disagreement across multiple fields. One area of contention is the role of single-subject design (SSD) research in providing scientific evidence. The debate about SSD's utility centers on three issues: sample size, effect size, and serial dependence. One potential…

  6. Critical Discourse Analysis and Science Education Texts: Employing Foucauldian Notions of Discourse and Subjectivity

    Science.gov (United States)

    Bazzul, Jesse

    2014-01-01

    This article supports critical, social justice oriented science education research by providing a theoretical and methodological basis for examining how subjectivities may be constituted through discourses found in science education texts. Such research explores how discourses orient teachers and students to the world, others, and themselves, as…

  7. Subband analysis and synthesis of real-world textures for objective and subjective determination of roughness

    NARCIS (Netherlands)

    Van Egmond, R.; Pappas, T.N.; De Ridder, H.

    2010-01-01

    In a previous study we investigated the roughness of real world textures taken from the CUReT database. We showed that people could systematically judge the subjective roughness of these textures. However, we did not determine which objective factors relate to these perceptual judgments of

  8. Entangled ontologies: a sociophilosophical analysis of technological artefacts, subjects, and bodies

    OpenAIRE

    Schyfter, Pablo

    2009-01-01

    Social studies of technology and particularly the sociology of technology have long explored the reticulations between technology and social life. More specifically, the sociology of technology has contributed numerous studies addressing the relationship between technological artefacts and the social order. Following this tradition, feminist studies of technology have developed robust analyses of technology and subjectivity, with particular attention given to questions of gender i...

  9. Ascertaining Activities in a Subject Area Through Bibliometric Analysis; Application to "Library Literature"

    Science.gov (United States)

    Saracevic, Tefko; Perk, Lawrence J.

    1973-01-01

    A combination of quantitative and qualitative techniques were used to analize the journal articles indexed in one volume of Library Literature.'' This approach, merging bibliometrics and classification, yielded results in such areas as dispersion of articles among journals, frequency of article type and types of subjects covered. (16 references)…

  10. WALKING SPEED OF NORMAL SUBJECTS AND AMPUTEES - ASPECTS OF VALIDITY OF GAIT ANALYSIS

    NARCIS (Netherlands)

    BOONSTRA, AM; FIDLER, [No Value; EISMA, WH

    This study investigated some aspects of the validity of walking speed recording in 15 normal subjects. 16 trans-femoral empathics and 8 knee disarticulation amputees. The variability and test-retest reliability of walking speed and the influence of simultaneous recording of EMG and goniometry on

  11. Subjective benefit after BAHA system application in patients with congenital unilateral conductive hearing impairment.

    NARCIS (Netherlands)

    Kunst, S.J.W.; Hol, M.K.S.; Mylanus, E.A.M.; Leijendeckers, J.M.; Snik, A.F.M.; Cremers, C.W.R.J.

    2008-01-01

    OBJECTIVE: To study whether unilateral Bone-anchored Hearing Aid (BAHA) fitting led to subjective hearing benefit in patients with congenital unilateral conductive hearing impairment. STUDY DESIGN: Prospective evaluation on 20 patients. SETTING: Tertiary referral center. PATIENTS: Ten adults and 10

  12. THE SYSTEM OF STATISTICAL OBJECTIVE AND SUBJECTIVE INDICATORS OF MEASURING QUALITY OF LIFE

    OpenAIRE

    I. Romaniuk

    2015-01-01

    This article examines approaches to defining and measuring quality of life. Each approach to measuring the quality of life contains information that is not contained in the other measures. It describes the economic, subjective and social indicators. The strengths and weaknesses of those indicators are also analyzed.

  13. Identification of hidden failures in process control systems through function-oriented system analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jalashgar, A.

    1997-05-01

    The main subject of this thesis is to identify hidden failures in process control systems by developing and using a function-oriented system analysis method. Qualitative failure analysis and the characteristics of the classical failure analysis methods and function-oriented modelling methods are covered. The general limitations of the methods in connection with the identification and representation of hidden failures are discussed. The discussion has led to the justification of developing and using a function-oriented system analysis method to identify and represent the capabilities of the system components, which realize different sets of functions in connection with different sets of goals that the system must achieve. A terminology is introduced to define the basic aspects of technical systems including goals, functions, capabilities and physical structure. A function-oriented system analysis method using this terminology and a tailored combination of the two function-oriented modelling approaches, is also introduced. It is then explained how the method can be applied in the identification and representation of hidden failures. The building blocks of a knowledge-oriented system to perform the diagnosis on the basis of the developed method are equally described. A prototype of the knowledge-based system is developed to demonstrate the applicability of the function-oriented system analysis method and the knowledge-based system. The prototype is implemented within the object-oriented software environment G2. (au) 65 ills., 32 refs.

  14. Two energy system analysis - tools

    DEFF Research Database (Denmark)

    Lund, Henrik; Andersen, Anders N.; Antonoff, Jayson

    2004-01-01

    The chapter illustrates some of the different types of problems that must be solved when analysing energy systems.......The chapter illustrates some of the different types of problems that must be solved when analysing energy systems....

  15. Stochastic Reachability Analysis of Hybrid Systems

    CERN Document Server

    Bujorianu, Luminita Manuela

    2012-01-01

    Stochastic reachability analysis (SRA) is a method of analyzing the behavior of control systems which mix discrete and continuous dynamics. For probabilistic discrete systems it has been shown to be a practical verification method but for stochastic hybrid systems it can be rather more. As a verification technique SRA can assess the safety and performance of, for example, autonomous systems, robot and aircraft path planning and multi-agent coordination but it can also be used for the adaptive control of such systems. Stochastic Reachability Analysis of Hybrid Systems is a self-contained and accessible introduction to this novel topic in the analysis and development of stochastic hybrid systems. Beginning with the relevant aspects of Markov models and introducing stochastic hybrid systems, the book then moves on to coverage of reachability analysis for stochastic hybrid systems. Following this build up, the core of the text first formally defines the concept of reachability in the stochastic framework and then...

  16. Smart hydroponic system growth analysis

    OpenAIRE

    Dolenc, Peter

    2017-01-01

    Hydroponic approach to growing plants has many benefits over conventional approach, such as: plants grow faster on smaller area and require less water. Hydroponic system usage in industry is quite well established, however, these systems are usually very specialized and complex. Home users can therefore mostly choose between oversimplified suboptimal or overly demanding hydroponic systems. As a solution to this problem a hydroponic system was designed which has all the capabilities of the com...

  17. Intraocular pressure following 18 hours of systemic dehydration in ocular normotensive healthy subjects

    Directory of Open Access Journals (Sweden)

    Faustina K. Idu

    2015-03-01

    Full Text Available Aim: To investigate the effect of dehydration on intraocular pressure (IOP. Subjects: The study population comprised 50 subjects (27 men and 23 women with a mean age of 42.84 ± 2.64 years.Method: The subjects dehydrated for 18 hours. IOP was assessed in both eyes using the Perkins handheld applanation tonometer. Baseline measurement of IOP was taken before the subjects dehydrated for 18 hours and repeated after dehydration. Blood samples were taken before and after dehydration for the determination of plasma osmolality and plasma antidiuretic hormone (ADH concentrations.Results: A statistically significant (p < 0.001 reduction in the mean weight of subjects occurred after dehydration. There was a significant reduction in IOP from 16.68 mmHg ± 0.32 mmHg to 13.08 mmHg ± 0.31 mmHg after dehydration (p < 0.001. Mean plasma osmolality showed a statistically significant increase (p < 0.05 from baseline of 290.02 mOsmol/kg ± 1.25 mOsmol/kg to 294.96 mOsmol/kg ± 1.33 mOsmol/kg after dehydration. There was also a significant increase (p < 0.05 in mean plasma ADH concentration from 5.36 pg/mL ± 0.21 pg/mL to 6.40 pg/mL ± 0.20 pg/mL after dehydration. There were no significant differences in both systolic and diastolic blood pressures before and after dehydration.Conclusion: Dehydration decreases IOP in healthy humans; this decrease probably results from an increase in plasma osmolality and plasma ADH concentrations.

  18. Temporal Patterns of Subjective Experiences and Self-Regulation during Ramadan Fasting among Elite Archers: A Qualitative Analysis.

    Science.gov (United States)

    Roy, Jolly; Hamidan, Shazarina; Singh, Rabindarjeet

    2011-09-01

    Some major competitions (e.g. London Olympics, 2012) are scheduled during the Ramadan fasting month. Little attention has been given to explore the archers' performance related subjective experiences with a qualitative method. Therefore, this study addressed individual archers' subjective experiences within the framework of self-regulation during Ramadan. Eleven elite Malaysian Muslim fasting archers volunteered to participate in the study. Grounded theory was the qualitative approach used to examine the subjective experiences of athletes during Ramadan. Interviews were conducted and inductive content analysis was adopted to identify the temporal patterns of self-regulation of subjective experiences across the fasting period. Inductive content analysis identified (a) physical, (b) mental,(c) emotional, (d) behavioral, and (e) spiritual experiences. Overall patterns revealed that experiences associated with physical, emotional, behavioral, and spiritual dimensions dominated in the first phase of fasting, while the mental dimension surfaced increasingly in the latter phase of fasting. The trend showed changes in the patterns of experiences among the major domains across the temporal dimension. Athletes reported increased subjective experiences in mental factors toward the latter half of the fasting period. Practitioners should emphasize on mental aspects of training, as these appear to be salient in archery performance.

  19. Properties of recoverable region and semi-global stabilization in recoverable region for linear systems subject to constraints

    NARCIS (Netherlands)

    Stoorvogel, Antonie Arij; Saberi, Ali; Shi, Guoyong

    This paper investigates time-invariant linear systems subject to input and state constraints. It is shown that the recoverable region (which is the largest domain of attraction that is theoretically achievable) can be semiglobally stabilized by continuous nonlinear feedbacks while satisfying the

  20. Properties of recoverable region and semi-global stabilization in recoverable region for linear systems subject to constraints

    NARCIS (Netherlands)

    Stoorvogel, Antonie Arij; Saberi, Ali; Shi, Guoyong

    This paper investigates linear systems subject to input and state constraints. It is shown that the recoverable region (which is the largest domain of attraction that is theoretically achievable) can be semiglobally stabilized by continuous nonlinear feedbacks while satisfying the constraints.

  1. The active disturbance rejection control approach to stabilisation of coupled heat and ODE system subject to boundary control matched disturbance

    Science.gov (United States)

    Guo, Bao-Zhu; Liu, Jun-Jun; AL-Fhaid, A. S.; Younas, Arshad Mahmood M.; Asiri, Asim

    2015-08-01

    We consider stabilisation for a linear ordinary differential equation system with input dynamics governed by a heat equation, subject to boundary control matched disturbance. The active disturbance rejection control approach is applied to estimate, in real time, the disturbance with both constant high gain and time-varying high gain. The disturbance is cancelled in the feedback loop. The closed-loop systems with constant high gain and time-varying high gain are shown, respectively, to be practically stable and asymptotically stable.

  2. Subjective thermal sensation and human body exergy consumption rate: analysis and correlation

    DEFF Research Database (Denmark)

    Simone, Angela; Dovjak, M.; Kolarik, Jakub

    2011-01-01

    , it is reasonable to consider both the exergy flows in building and those within the human body. There is a need to verify the human-body exergy model with the Thermal-Sensation (TS) response of subjects exposed to different combinations of indoor climate parameters (temperature, humidity, etc.). First results...... available on the relation between human-body exergy consumption rates and subjectively assessed thermal sensation showed that the minimum human body exergy consumption rate is associated with thermal sensation votes close to thermal neutrality, tending to slightly cool side of thermal sensation. By applying...... the exergy concept to the built indoor environment, additional results are going to be explored. By using the data available so far of operative temperature (to), the human body exergy consumption rates increase as to increases above 24°C or decreases below 22°C at relative humidity (RH) lower than 50...

  3. Laparoscopic Sacropexy: A Retrospective Analysis of the Subjective Outcome in 310 Cases

    Directory of Open Access Journals (Sweden)

    B. Bojahr

    2012-01-01

    Full Text Available Background and Objective. The aim of this study was to assess the subjective outcome following laparoscopic sacropexy. Methods. We performed a retrospective cohort study among women treated for descensus with laparoscopic sacropexy between January 2000 and December 2007. 310 patients received questionnaires during followup assessing major pre- and postoperative symptoms and overall satisfaction. Results. 214 (69% patients responded to the questionnaire. Mean followup was 24.5 months. The number of patients with back or lower abdominal pain, foreign body sensation in the vagina and prolapse-related symptoms, urinary symptoms, vaginal and bladder infections, and the need for pessary usage decreased significantly postsurgically. Bowel symptoms increased slightly but not significantly. Two years after surgery, nearly 2 thirds of the women were satisfied or very satisfied with the outcome. Conclusion. Laparoscopic sacropexy is an effective treatment of descensus, with favorable or satisfactory subjective outcomes.

  4. A token economy for exercise adherence in pediatric cystic fibrosis: a single-subject analysis.

    Science.gov (United States)

    Bernard, Rebecca S; Cohen, Lindsey L; Moffett, Kathryn

    2009-05-01

    In cystic fibrosis (CF), adherence to airway clearance techniques (e.g., chest physiotherapy and exercise) is poor. Exercise is important because pulmonary difficulties are associated with the highest mortality rate. Despite this, very little research has focused on exercise adherence in CF. This study examined a token economy for increasing exercise in children with CF. An ABAB single-subject design evaluated a token economy for increasing and maintaining exercise in three children with CF. Patient report, parent report, and physiological measures were used to assess treatment integrity, medical stability, and changes in exercise. Measures suggested that treatment integrity was strong. Results indicated strong treatment effects for all participants without negative medical side effects. Follow-up of 1 and 3 months supported continued exercise for all participants. A token economy effectively increased exercise in children with CF, and the single-subject design highlighted some of the intricacies of individualized treatment of adherence. Implications and recommendations for further research are discussed.

  5. Two sustainable energy system analysis models

    DEFF Research Database (Denmark)

    Lund, Henrik; Goran Krajacic, Neven Duic; da Graca Carvalho, Maria

    2005-01-01

    This paper presents a comparative study of two energy system analysis models both designed with the purpose of analysing electricity systems with a substantial share of fluctuating renewable energy....

  6. New Tools in Nonlinear System Analysis

    National Research Council Canada - National Science Library

    Megretski, Alexandre

    2003-01-01

    This project was aimed at developing novel theories for the analysis and design of systems exhibiting essentially nonlinear behavior, such as systems utilizing quantized decision making, periodic orbits, switching, etc...

  7. Risk and safety analysis of nuclear systems

    National Research Council Canada - National Science Library

    Lee, John C; McCormick, Norman J

    2011-01-01

    ...), and failure modes of systems. All of this material is general enough that it could be used in non-nuclear applications, although there is an emphasis placed on the analysis of nuclear systems...

  8. Subjective Evaluation of the Microenvironment Generated by a Hospital Bed with Localized Ventilation System

    DEFF Research Database (Denmark)

    Kehayova, Nushka; Bolashikov, Zhecho Dimitrov; Melikov, Arsen Krikor

    2016-01-01

    A novel method for local hospital bed ventilation, called HBIVCU (Hospital Bed with Integrated Ventilation and Cleansing Unit), was studied in a human subject experiment. The goal of this study was to identify human response to the microenvironment generated by a hospital bed with installed HBIVCU...... and to compare with human response to the micro-environment at a hospital bed without local ventilation. 32 participants took part in two experimental conditions - hospital bed with and without installed HBIVCU. Subject’s votes on the bed microenvironment were collected via standardized questionnaires....... The subjects evaluated the perceived air quality in the ventilated bed as better compared to that in the non-ventilated bed. The whole body thermal sensation (WTS) and acceptability votes were decreasing over time for the non-ventilated bed condition. Significant differences in the local thermal sensation LTS...

  9. Analysis of the Precautionary Saving Motive Based on a Subjective Measure : (SAVE 2005-2007)

    OpenAIRE

    Ziegelmeyer, Michael

    2009-01-01

    The importance of the precautionary saving motive for households’ saving behaviour is unquestioned in the literature of the last two decades. However, the magnitude of precautionary savings and its influencing factors could not be satisfactorily determined. A subjective measure of the desired amount of precautionary savings in the German SAVE study 2005-2007 allows for the evaluation of these questions on a new basis without relying on a specific definition of wealth. This study supports the ...

  10. Favored subjects and psychosocial needs in music therapy in terminally ill cancer patients: a content analysis

    OpenAIRE

    Preissler, Pia; Kordovan, Sarah; Ullrich, Anneke; Bokemeyer, Carsten; Oechsle, Karin

    2016-01-01

    Background Research has shown positive effects of music therapy on the physical and mental well-being of terminally ill patients. This study aimed to identify favored subjects and psychosocial needs of terminally ill cancer patients during music therapy and associated factors. Methods Forty-one Patients receiving specialized inpatient palliative care prospectively performed a music therapy intervention consisting of at least two sessions (total number of sessions: 166; per patient average: 4,...

  11. Analysis of spatial mobility in subjects from a Dengue endemic urban locality in Morelos State, Mexico.

    Science.gov (United States)

    Falcón-Lezama, Jorge Abelardo; Santos-Luna, René; Román-Pérez, Susana; Martínez-Vega, Ruth Aralí; Herrera-Valdez, Marco Arieli; Kuri-Morales, Ángel Fernando; Adams, Ben; Kuri-Morales, Pablo Antonio; López-Cervantes, Malaquías; Ramos-Castañeda, José

    2017-01-01

    Mathematical models and field data suggest that human mobility is an important driver for Dengue virus transmission. Nonetheless little is known on this matter due the lack of instruments for precise mobility quantification and study design difficulties. We carried out a cohort-nested, case-control study with 126 individuals (42 cases, 42 intradomestic controls and 42 population controls) with the goal of describing human mobility patterns of recently Dengue virus-infected subjects, and comparing them with those of non-infected subjects living in an urban endemic locality. Mobility was quantified using a GPS-data logger registering waypoints at 60-second intervals for a minimum of 15 natural days. Although absolute displacement was highly biased towards the intradomestic and peridomestic areas, occasional displacements exceeding a 100-Km radius from the center of the studied locality were recorded for all three study groups and individual displacements were recorded traveling across six states from central Mexico. Additionally, cases had a larger number of visits out of the municipality´s administrative limits when compared to intradomestic controls (cases: 10.4 versus intradomestic controls: 2.9, p = 0.0282). We were able to identify extradomestic places within and out of the locality that were independently visited by apparently non-related infected subjects, consistent with houses, working and leisure places. Results of this study show that human mobility in a small urban setting exceeded that considered by local health authority's administrative limits, and was different between recently infected and non-infected subjects living in the same household. These observations provide important insights about the role that human mobility may have in Dengue virus transmission and persistence across endemic geographic areas that need to be taken into account when planning preventive and control measures. Finally, these results are a valuable reference when setting the

  12. Designing oversight for nanomedicine research in human subjects: systematic analysis of exceptional oversight for emerging technologies

    Science.gov (United States)

    Wolf, Susan M.; Jones, Cortney M.

    2011-04-01

    The basic procedures and rules for oversight of U.S. human subjects research have been in place since 1981. Certain types of human subjects research, however, have provoked creation of additional mechanisms and rules beyond the Department of Health & Human Services (DHHS) Common Rule and Food and Drug Administration (FDA) equivalent. Now another emerging domain of human subjects research—nanomedicine—is prompting calls for extra oversight. However, in 30 years of overseeing research on human beings, we have yet to specify what makes a domain of scientific research warrant extra oversight. This failure to systematically evaluate the need for extra measures, the type of extra measures appropriate for different challenges, and the usefulness of those measures hampers efforts to respond appropriately to emerging science such as nanomedicine. This article evaluates the history of extra oversight, extracting lessons for oversight of nanomedicine research in human beings. We argue that a confluence of factors supports the need for extra oversight, including heightened uncertainty regarding risks, fast-evolving science yielding complex and increasingly active materials, likelihood of research on vulnerable participants including cancer patients, and potential risks to others beyond the research participant. We suggest the essential elements of the extra oversight needed.

  13. Designing Oversight for Nanomedicine Research in Human Subjects: Systematic Analysis of Exceptional Oversight for Emerging Technologies

    Science.gov (United States)

    Wolf, Susan M.; Jones, Cortney

    2012-01-01

    The basic procedures and rules for oversight of U.S. human subjects research have been in place since 1981. Certain types of human subjects research, however, have provoked creation of additional mechanisms and rules beyond the Department of Health & Human Services (DHHS) Common Rule and Food and Drug Administration (FDA) equivalent. Now another emerging domain of human subjects research—nanomedicine—is prompting calls for extra oversight. However, in 30 years of overseeing research on human beings, we have yet to specify what makes a domain of scientific research warrant extra oversight. This failure to systematically evaluate the need for extra measures, the type of extra measures appropriate for different challenges, and the usefulness of those measures hampers efforts to respond appropriately to emerging science such as nanomedicine. This article evaluates the history of extra oversight, extracting lessons for oversight of nanomedicine research in human beings. We argue that a confluence of factors supports the need for extra oversight, including heightened uncertainty regarding risks, fast-evolving science yielding complex and increasingly active materials, likelihood of research on vulnerable participants including cancer patients, and potential risks to others beyond the research participant. We suggest the essential elements of the extra oversight needed. PMID:23226969

  14. Power system stability modelling, analysis and control

    CERN Document Server

    Sallam, Abdelhay A

    2015-01-01

    This book provides a comprehensive treatment of the subject from both a physical and mathematical perspective and covers a range of topics including modelling, computation of load flow in the transmission grid, stability analysis under both steady-state and disturbed conditions, and appropriate controls to enhance stability.

  15. Communication Systems Analysis Laboratory (CSAL)

    Data.gov (United States)

    Federal Laboratory Consortium — CSAL conducts electronic warfare investigations of radio frequency communication systems with respect to current and emerging electronic warfare threats. CSAL uses...

  16. Identification systems subject to plan cybersecurity; Identificacion de sistemas sujetos al plan de Ciberseguridad

    Energy Technology Data Exchange (ETDEWEB)

    Guerrero Sanz, J.; Perez Alcaniz, T.; Garcia Garcia, I.

    2012-07-01

    The implementation of a Plan Cybersecurity ensures that systems and communications networks that perform functions related to both physical security such emergency action and their support systems, and interfaces that may affect them, are protected with an effective system against cyber attacks.

  17. Transient Analysis of Manufacturing Systems Performance

    OpenAIRE

    Narahari, Y.; Viswanadham, N

    1994-01-01

    Studies in performance evaluation of automated manufacturing systems, using simulation or analytical models,have always emphasized steady-state or equilibrium performance in preference to transient performance. In this study, we present several situations in manufacturing systems where transient analysis is very important. Manufacturing systems and models in which such situations arise include: systems with failure states and deadlocks, unstable queueing systems, and systems with fluctuating ...

  18. EBT data acquisition and analysis system

    Energy Technology Data Exchange (ETDEWEB)

    Burris, R.D.; Greenwood, D.E.; Stanton, J.S.; Geoffroy, K.A.

    1980-10-01

    This document describes the design and implementation of a data acquisition and analysis system for the EBT fusion experiment. The system includes data acquisition on five computers, automatic transmission of that data to a large, central data base, and a powerful data retrieval system. The system is flexible and easy to use, and it provides a fully documented record of the experiments.

  19. Analysis of MTHFR and MTRR Gene Polymorphisms in Iranian Ventricular Septal Defect Subjects

    Directory of Open Access Journals (Sweden)

    Ali Etemad

    2013-01-01

    Full Text Available Ventricular septal defect (VSD is one of the most common types of congenital heart defects (CHD. There are vivid multifactorial causes for VSD in which both genetic and environmental risk factors are consequential in the development of CHD. Methionine synthase reductase (MTRR and methylenetetrahydrofolate reductase (MTHFR are two of the key regulatory enzymes involved in the metabolic pathway of homocysteine. Genes involved in homocysteine/folate metabolism may play an important role in CHDs. In this study; we determined the association of A66G and C524T polymorphisms of the MTRR gene and C677T polymorphism of the MTHFR gene in Iranian VSD subjects. A total of 123 children with VSDs and 125 healthy children were included in this study. Genomic DNA was extracted from the buccal cells of all the subjects. The restriction fragment length polymorphism polymerase chain reaction (PCR-RFLP method was carried out to amplify the A66G and C524T polymorphism of MTRR and C677T polymorphism of MTHFR genes digested with Hinf1, Xho1 and Nde1 enzymes, respectively. The genotype frequencies of CC, CT and TT of MTRR gene among the studied cases were 43.1%, 40.7% and 16.3%, respectively, compared to 52.8%, 43.2% and 4.0%, respectively among the controls. For the MTRR A66G gene polymorphism, the genotypes frequencies of AA, AG and GG among the cases were 33.3%, 43.9% and 22.8%, respectively, while the frequencies were 49.6%, 42.4% and 8.0%, respectively, among control subjects. The frequencies for CC and CT genotypes of the MTHFR gene were 51.2% and 48.8%, respectively, in VSD patients compared to 56.8% and 43.2% respectively, in control subjects. Apart from MTHFR C677T polymorphism, significant differences were noticed (p < 0.05 in C524T and A66G polymorphisms of the MTRR gene between cases and control subjects.

  20. Simulation and Analysis of Roller Chain Drive Systems

    DEFF Research Database (Denmark)

    Pedersen, Sine Leergaard

    The subject of this thesis is simulation and analysis of large roller chain drive systems, such as e.g. used in marine diesel engines. The aim of developing a chain drive simulation program is to analyse dynamic phenomena of chain drive systems and investigate different design changes...... with a real tooth profile proves superior to other applied models. With this model it is possible to perform a dynamic simulation of large marine engine chain drives. Through the application of this method, it is shown that the interrelated dynamics of the elements in the chain drive system is captured...... systems other phenomena occur and therefore, a specific model of the marine engine chain drive is of interest. The research objective of the work presented in this thesis is to contribute with a novel theoretical basis for the analysis of chain drive systems, by posing and validating different...

  1. Systemic Analysis Approaches for Air Transportation

    Science.gov (United States)

    Conway, Sheila

    2005-01-01

    Air transportation system designers have had only limited success using traditional operations research and parametric modeling approaches in their analyses of innovations. They need a systemic methodology for modeling of safety-critical infrastructure that is comprehensive, objective, and sufficiently concrete, yet simple enough to be used with reasonable investment. The methodology must also be amenable to quantitative analysis so issues of system safety and stability can be rigorously addressed. However, air transportation has proven itself an extensive, complex system whose behavior is difficult to describe, no less predict. There is a wide range of system analysis techniques available, but some are more appropriate for certain applications than others. Specifically in the area of complex system analysis, the literature suggests that both agent-based models and network analysis techniques may be useful. This paper discusses the theoretical basis for each approach in these applications, and explores their historic and potential further use for air transportation analysis.

  2. Sleep in children with attention-deficit/hyperactivity disorder: meta-analysis of subjective and objective studies.

    Science.gov (United States)

    Cortese, Samuele; Faraone, Stephen V; Konofal, Eric; Lecendreux, Michel

    2009-09-01

    To perform a meta-analysis of subjective (i.e., based on questionnaires) and objective (i.e., using polysomnography or actigraphy) studies comparing sleep in children with attention-deficit/hyperactivity disorder (ADHD) versus controls. We searched for subjective and objective sleep studies (1987-2008) in children with ADHD (diagnosed according to standardized criteria). Studies including subjects pharmacologically treated or with comorbid anxiety/depressive disorders were excluded. Sixteen studies, providing 9 subjective and 15 objective parameters and including a total pooled sample of 722 children with ADHD versus 638 controls, were retained. With regard to subjective items, the meta-analysis indicated that children with ADHD had significantly higher bedtime resistance (z = 6.94, p breathing (z = 2.05, p =.040), and daytime sleepiness (z = 1.96, p =.050) compared with the controls. As for objective parameters, sleep onset latency (on actigraphy), the number of stage shifts/hour sleep, and the apnea-hypopnea index were significantly higher in the children with ADHD compared with the controls (z = 3.44, p =.001; z = 2.43, p =.015; z = 3.47, p =.001, respectively). The children with ADHD also had significantly lower sleep efficiency on polysomnography (z = 2.26, p =.024), true sleep time on actigraphy (z = 2.85, p =.004), and average times to fall asleep for the Multiple Sleep Latency Test (z = 6.37, p children with ADHD are significantly more impaired than the controls in most of the subjective and some of the objective sleep measures. These results lay the groundwork for future evidence-based guidelines on the management of sleep disturbances in children with ADHD.

  3. Achilles tendon stress is more sensitive to subject-specific geometry than subject-specific material properties: A finite element analysis.

    Science.gov (United States)

    Hansen, Wencke; Shim, Vickie B; Obst, Steven; Lloyd, David G; Newsham-West, Richard; Barrett, Rod S

    2017-05-03

    This study used subject-specific measures of three-dimensional (3D) free Achilles tendon geometry in conjunction with a finite element method to investigate the effect of variation in subject-specific geometry and subject-specific material properties on tendon stress during submaximal isometric loading. Achilles tendons of eight participants (Aged 25-35years) were scanned with freehand 3D ultrasound at rest and during a 70% maximum voluntary isometric contraction. Ultrasound images were segmented, volume rendered and transformed into subject-specific 3D finite element meshes. The mean (±SD) lengths, volumes and cross-sectional areas of the tendons at rest were 62±13mm, 3617±984mm3 and 58±11mm2 respectively. The measured tendon strain at 70% MVIC was 5.9±1.3%. Subject-specific material properties were obtained using an optimisation approach that minimised the difference between measured and modelled longitudinal free tendon strain. Generic geometry was represented by the average mesh and generic material properties were taken from the literature. Local stresses were subsequently computed for combinations of subject-specific and generic geometry and material properties. For a given geometry, changing from generic to subject-specific material properties had little effect on the stress distribution in the tendon. In contrast, changing from generic to subject-specific geometry had a 26-fold greater effect on tendon stress distribution. Overall, these findings indicate that the stress distribution experienced by the living free Achilles tendon of a young and healthy population during voluntary loading are more sensitive to variation in tendon geometry than variation in tendon material properties. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. The influence of subjective norm on intention to use of learning management system among Malaysian higher education students

    Science.gov (United States)

    Baleghi-Zadeh, Sousan; Ayub, Ahmad Fauzi Mohd; Mahmud, Rosnaini; Daud, Shaffe Mohd

    2014-12-01

    In recent years, the use of learning management system by universities has been increasingly growing. However, the results of several studies have revealed that students do not fully use the information systems. The present study proposes a model which investigates the influence of three constructs of perceived ease of use, perceived usefulness, and subjective norm on behavior intention to use of learning management system. The sample size was 216 Malaysian undergraduate students. The results of the study revealed that the proposed model accounts for 31.1 % variance of behavior intention to use.

  5. The Effects of the Disturbance of the Vestibular System on the Dynamic Balance of Idiopathic Scoliotic Subjects with and Without Exercise Therapy Compared to Healthy Subjects

    Directory of Open Access Journals (Sweden)

    N. Farahpour

    2004-01-01

    Full Text Available The mechanism of the neuromuscular system’s disorders in Adolescent Idiopathic Scoliosis (AIS are not well known. The objectives of this study were to assess the dynamic balance of the AIS patients and the influence of exercise therapy on patients' dynamic balance. Eleven teenager scoliotic subjects after three months exercise therapy, nine similar patients without therapy and 13 healthy age matched subjects as control group were studied. Using dynamic stability platform, the deviation of COG of subjects in different positions, including up right standing, standing with head flexion and standing with head hyper extension were measured. The tests were repeated in both lose and stable condition of the foot platform. Results showed that the stability of the foot platform resulted in COG's deviation by 1.13 0.08 in all subjects. Dynamic balance of scoliotic patients without treatment was similar to that of the normal subjects. While, exercised patients had less COG deviation than the other groups. The change in head position increased the COG deviation by 2.5 times in control and non-exercised patients and 1.5 times in exercised patients. The dynamic balance in scoliosis was not affected. Exercise improved the dynamic balance in scoliotic subjects. Exercise therapy is recommended to improve the proprioceptives function.

  6. Wavelet cross-correlation and phase analysis of a free cantilever subjected to band excitation

    Directory of Open Access Journals (Sweden)

    Francesco Banfi

    2012-03-01

    Full Text Available This work introduces the concept of time–frequency map of the phase difference between the cantilever response signal and the driving signal, calculated with a wavelet cross-correlation technique. The wavelet cross-correlation quantifies the common power and the relative phase between the response of the cantilever and the exciting driver, yielding “instantaneous” information on the driver-response phase delay as a function of frequency. These concepts are introduced through the calculation of the response of a free cantilever subjected to continuous and impulsive excitation over a frequency band.

  7. Meta-analysis of subjective complaints of vertigo and vestibular tests after cochlear implantation.

    Science.gov (United States)

    Hänsel, Toni; Gauger, Ulrich; Bernhard, Nikolai; Behzadi, Nina; Romo Ventura, Maria Eugenia; Hofmann, Veit; Olze, Heidi; Knopke, Steffen; Todt, Ingo; Coordes, Annekatrin

    2018-01-04

    Postoperative vertigo is a common complaint after cochlear implantation, but published incidence rates differ vastly. The aim of the present study was to investigate both subjective complaints of vertigo before and after cochlear implantation and related vestibular diagnostic tests on cochlear implant candidates. We performed a systematic literature search according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement in PubMed, Cochrane Register, and EMBASE. We presented 116 eligible studies investigating subjective complaints of vertigo after cochlear implantation and/or related vestibular diagnostic tests. We conducted three meta-analyses of 46 eligible studies with matched pre- and postoperative data to calculate the odds ratio of new vertigo onset, as well as the impairment of vestibular receptors measured by nystagmography and cervical vestibular evoked myogenic potentials (cVEMP). Postoperative vertigo was calculated from 95 studies and further subdivided by mean age with pooled data. We observed a significant increase in postoperative vertigo and significant impairment of nystagmography and cVEMP detection. Vertigo after cochlear implantation was reported in 9.3% of the patients with a continuous increase in patient age at surgery. In a subgroup of studies, new onset of vertigo was found in 17.4% of the patients. In addition, 7.2% of the patients had persisting vertigo complaints, whereas 11.6% described an altered vertigo quality and 7.7% had their preoperative complaints resolved. A comparison of round window approach and cochleostomy revealed significantly increased vertigo after cochleostomy. Both insertion methods showed similar effects in nystagmography and cVEMP testing. Cochlear implantation has a significant impact on subjective vertigo and vestibular receptor function. This is affected by the patient's age at the time of surgery. The surgical technique (round window or cochleostomy) may influence the outcome, but

  8. Imputation of the Date of HIV Seroconversion in a Cohort of Seroprevalent Subjects: Implications for Analysis of Late HIV Diagnosis

    Directory of Open Access Journals (Sweden)

    Paz Sobrino-Vegas

    2012-01-01

    Full Text Available Objectives. Since subjects may have been diagnosed before cohort entry, analysis of late HIV diagnosis (LD is usually restricted to the newly diagnosed. We estimate the magnitude and risk factors of LD in a cohort of seroprevalent individuals by imputing seroconversion dates. Methods. Multicenter cohort of HIV-positive subjects who were treatment naive at entry, in Spain, 2004–2008. Multiple-imputation techniques were used. Subjects with times to HIV diagnosis longer than 4.19 years were considered LD. Results. Median time to HIV diagnosis was 2.8 years in the whole cohort of 3,667 subjects. Factors significantly associated with LD were: male sex; Sub-Saharan African, Latin-American origin compared to Spaniards; and older age. In 2,928 newly diagnosed subjects, median time to diagnosis was 3.3 years, and LD was more common in injecting drug users. Conclusions. Estimates of the magnitude and risk factors of LD for the whole cohort differ from those obtained for new HIV diagnoses.

  9. Low cost real time interactive analysis system

    Science.gov (United States)

    Stetina, F.

    1988-01-01

    Efforts continue to develop a low cost real time interactive analysis system for the reception of satellite data. A multi-purpose ingest hardware software frame formatter was demonstrated for GOES and TIROS data and work is proceeding on extending the capability to receive GMS data. A similar system was proposed as an archival and analysis system for use with INSAT data and studies are underway to modify the system to receive the planned SeaWiFS (ocean color) data. This system was proposed as the core of a number of international programs in support of U.S. AID activities. Systems delivered or nearing final testing are listed.

  10. Single-subject independent component analysis-based intensity normalization in non-quantitative multi-modal structural MRI.

    Science.gov (United States)

    Papazoglou, Sebastian; Würfel, Jens; Paul, Friedemann; Brandt, Alexander U; Scheel, Michael

    2017-04-22

    Non-quantitative MRI is prone to intersubject intensity variation rendering signal intensity level based analyses limited. Here, we propose a method that fuses non-quantitative routine T1-weighted (T1w), T2w, and T2w fluid-saturated inversion recovery sequences using independent component analysis and validate it on age and sex matched healthy controls. The proposed method leads to consistent and independent components with a significantly reduced coefficient-of-variation across subjects, suggesting potential to serve as automatic intensity normalization and thus to enhance the power of intensity based statistical analyses. To exemplify this, we show that voxelwise statistical testing on single-subject independent components reveals in particular a widespread sex difference in white matter, which was previously shown using, for example, diffusion tensor imaging but unobservable in the native MRI contrasts. In conclusion, our study shows that single-subject independent component analysis can be applied to routine sequences, thereby enhancing comparability in-between subjects. Unlike quantitative MRI, which requires specific sequences during acquisition, our method is applicable to existing MRI data. Hum Brain Mapp, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  11. Geographic Information System Data Analysis

    Science.gov (United States)

    Billings, Chad; Casad, Christopher; Floriano, Luis G.; Hill, Tracie; Johnson, Rashida K.; Locklear, J. Mark; Penn, Stephen; Rhoulac, Tori; Shay, Adam H.; Taylor, Antone; hide

    1995-01-01

    Data was collected in order to further NASA Langley Research Center's Geographic Information System(GIS). Information on LaRC's communication, electrical, and facility configurations was collected. Existing data was corrected through verification, resulting in more accurate databases. In addition, Global Positioning System(GPS) points were used in order to accurately impose buildings on digitized images. Overall, this project will help the Imaging and CADD Technology Team (ICTT) prove GIS to be a valuable resource for LaRC.

  12. Analysis of morphological characteristics and expression levels of extracellular matrix proteins in skin wounds to determine wound age in living subjects in forensic medicine.

    Science.gov (United States)

    Fronczek, Judith; Lulf, Ronald; Korkmaz, H Ibrahim; Witte, Birgit I; van de Goot, Franklin R W; Begieneman, Mark P V; Krijnen, Paul A J; Rozendaal, Lawrence; Niessen, Hans W M; Reijnders, Udo J L

    2015-01-01

    Wound age determination in living subjects is important in routine diagnostics in forensic medicine. Macroscopical description of a wound to determine wound age however is inadequate. The aim of this study was to assess whether it would be feasible to determine wound age via analysis of morphological characteristics and extracellular matrix proteins in skin biopsies of living subjects referred to a forensic outpatient clinic. Skin biopsies (n=101), representing the border area of the wound, were taken from skin injuries of known wound age (range: 4.5h-25 days) in living subjects. All biopsies were analyzed for 3 morphological features (ulceration, parakeratosis and hemorrhage) and 3 extracellular matrix markers (collagen III, collagen IV and α-SMA). For quantification, biopsies were subdivided in 4 different timeframes: 0.2-2 days, 2-4 days, 4-10 days and 10-25 days old wounds. Subsequently, a probability scoring system was developed. For hemorrhage, collagen III, collagen IV and α-SMA expression no relation with wound age was found. Ulceration was only found in wounds of 0.2-2, 2-4 and 4-10 days old, implying that the probability that a wound was more than 10 days old in case of ulceration is equal to 0%. Also parakeratosis was almost exclusively found in wounds of 0.2-2, 2-4 and 4-10 days old, except for one case with a wound age of 15 days old. The probability scoring system of all analyzed markers, as depicted above, however can be used to calculate individual wound age probabilities in biopsies of skin wounds of living subjects. We have developed a probability scoring system, analysing morphological characteristics and extracellular matrix proteins in superficial skin biopsies of wounds in living subjects that can be applied in forensic medicine for wound age determination. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  13. Probabilistic sensitivity analysis of biochemical reaction systems.

    Science.gov (United States)

    Zhang, Hong-Xuan; Dempsey, William P; Goutsias, John

    2009-09-07

    Sensitivity analysis is an indispensable tool for studying the robustness and fragility properties of biochemical reaction systems as well as for designing optimal approaches for selective perturbation and intervention. Deterministic sensitivity analysis techniques, using derivatives of the system response, have been extensively used in the literature. However, these techniques suffer from several drawbacks, which must be carefully considered before using them in problems of systems biology. We develop here a probabilistic approach to sensitivity analysis of biochemical reaction systems. The proposed technique employs a biophysically derived model for parameter fluctuations and, by using a recently suggested variance-based approach to sensitivity analysis [Saltelli et al., Chem. Rev. (Washington, D.C.) 105, 2811 (2005)], it leads to a powerful sensitivity analysis methodology for biochemical reaction systems. The approach presented in this paper addresses many problems associated with derivative-based sensitivity analysis techniques. Most importantly, it produces thermodynamically consistent sensitivity analysis results, can easily accommodate appreciable parameter variations, and allows for systematic investigation of high-order interaction effects. By employing a computational model of the mitogen-activated protein kinase signaling cascade, we demonstrate that our approach is well suited for sensitivity analysis of biochemical reaction systems and can produce a wealth of information about the sensitivity properties of such systems. The price to be paid, however, is a substantial increase in computational complexity over derivative-based techniques, which must be effectively addressed in order to make the proposed approach to sensitivity analysis more practical.

  14. Modal analysis of human body vibration model for Indian subjects under sitting posture.

    Science.gov (United States)

    Singh, Ishbir; Nigam, S P; Saran, V H

    2015-01-01

    Need and importance of modelling in human body vibration research studies are well established. The study of biodynamic responses of human beings can be classified into experimental and analytical methods. In the past few decades, plenty of mathematical models have been developed based on the diverse field measurements to describe the biodynamic responses of human beings. In this paper, a complete study on lumped parameter model derived from 50th percentile anthropometric data for a seated 54- kg Indian male subject without backrest support under free un-damped conditions has been carried out considering human body segments to be of ellipsoidal shape. Conventional lumped parameter modelling considers the human body as several rigid masses interconnected by springs and dampers. In this study, concept of mass of interconnecting springs has been incorporated and eigenvalues thus obtained are found to be closer to the values reported in the literature. Results obtained clearly establish decoupling of vertical and fore-and-aft oscillations. The mathematical modelling of human body vibration studies help in validating the experimental investigations for ride comfort of a sitting subject. This study clearly establishes the decoupling of vertical and fore-and-aft vibrations and helps in better understanding of possible human response to single and multi-axial excitations.

  15. Accelerometer based analysis of gait initiation failure in advanced juvenile parkinsonism: a single subject study.

    Science.gov (United States)

    Ishii, Mitsuaki; Mashimo, Hideaki

    2016-11-01

    [Purpose] This study used an accelerometer placed close to the center of gravity to quantitatively investigate whether unexpected gait initiation aggravates start hesitation (freezing of gait in gait initiation). [Subject and Methods] The subject was a 53-year-old female who had been suffering from juvenile parkinsonism since she was aged 21 years. An alternating-treatment design was used to compare acceleration characteristics under two gait initiation conditions, which were 1) deliberate gait initiation and 2) gait initiation on a sudden "go" verbal command (sudden gait initiation), in the "on" state of the medication cycle. [Results] In six out of eight sessions, a combination of reduced peak positive anterior accelerations and large power percentage in the high frequency band was consistently observed in the sudden gait initiation compared with deliberate gait initiation. In the other two sessions, although a large acceleration just after the "go" signal was observed, subsequent acceleration signals were blocked by sudden gait initiation. [Conclusion] The results suggest that, even in the "on" state, start hesitation is apparent without increased reliance on frontal cortical attentional mechanisms to compensate for impaired automaticity. In advanced juvenile parkinsonism, sudden gait initiation may be an effective paradigm as a provoking test for start hesitation.

  16. The outcome of tuberculosis treatment in subjects with chronic kidney disease in Brazil: a multinomial analysis

    Directory of Open Access Journals (Sweden)

    Barbara Reis-Santos

    2013-09-01

    Full Text Available OBJECTIVE: To analyze the association between clinical/epidemiological characteristics and outcomes of tuberculosis treatment in patients with concomitant tuberculosis and chronic kidney disease (CKD in Brazil. METHODS: We used the Brazilian Ministry of Health National Case Registry Database to identify patients with tuberculosis and CKD, treated between 2007 and 2011. The tuberculosis treatment outcomes were compared with epidemiological and clinical characteristics of the subjects using a hierarchical multinomial logistic regression model, in which cure was the reference outcome. RESULTS: The prevalence of CKD among patients with tuberculosis was 0.4% (95% CI: 0.37-0.42%. The sample comprised 1,077 subjects. The outcomes were cure, in 58%; treatment abandonment, in 7%; death from tuberculosis, in 13%; and death from other causes, in 22%. The characteristics that differentiated the ORs for treatment abandonment or death were age; alcoholism; AIDS; previous noncompliance with treatment; transfer to another facility; suspected tuberculosis on chest X-ray; positive results in the first smear microscopy; and indications for/use of directly observed treatment, short-course strategy. CONCLUSIONS: Our data indicate the importance of sociodemographic characteristics for the diagnosis of tuberculosis in patients with CKD and underscore the need for tuberculosis control strategies targeting patients with chronic noncommunicable diseases, such as CKD.

  17. Introducing axonal myelination in connectomics: A preliminary analysis of g-ratio distribution in healthy subjects.

    Science.gov (United States)

    Mancini, Matteo; Giulietti, Giovanni; Dowell, Nicholas; Spanò, Barbara; Harrison, Neil; Bozzali, Marco; Cercignani, Mara

    2017-09-14

    Microstructural imaging and connectomics are two research areas that hold great potential for investigating brain structure and function. Combining these two approaches can lead to a better and more complete characterization of the brain as a network. The aim of this work is characterizing the connectome from a novel perspective using the myelination measure given by the g-ratio. The g-ratio is the ratio of the inner to the outer diameters of a myelinated axon, whose aggregated value can now be estimated in vivo using MRI. In two different datasets of healthy subjects, we reconstructed the structural connectome and then used the g-ratio estimated from diffusion and magnetization transfer data to characterize the network structure. Significant characteristics of g-ratio weighted graphs emerged. First, the g-ratio distribution across the edges of the graph did not show the power-law distribution observed using the number of streamlines as a weight. Second, connections involving regions related to motor and sensory functions were the highest in myelin content. We also observed significant differences in terms of the hub structure and the rich-club organization suggesting that connections involving hub regions present higher myelination than peripheral connections. Taken together, these findings offer a characterization of g-ratio distribution across the connectome in healthy subjects and lay the foundations for further investigating plasticity and pathology using a similar approach. Copyright © 2017. Published by Elsevier Inc.

  18. Systems Analysis Department. Annual Report 2000

    Energy Technology Data Exchange (ETDEWEB)

    Duijm, N.J.; Jensen, E.; Larsen, H.; Olsson, C.

    2001-05-01

    This report describes the work of the Systems Analysis Department at Risoe National Laboratory during 2000. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning - UNEP Centre, Safety, Reliability and Human Factors, and Technology Scenarios. The report includes summary statistics and lists of publications, committees and staff members. (au)

  19. System Analysis Department. Annual Report 2002

    Energy Technology Data Exchange (ETDEWEB)

    Duijm, N.J.; Jensen, E.; Larsen, H.; Skipper, S. (eds.)

    2002-04-01

    This report describes the work of the Systems Analysis Department at Risoe National Laboratory during 2001. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning - UNEP Centre, Safety, Reliability and Human Factors, and Technology Scenarios. The report includes summary statistics and lists of publications, committees and staff members. (au)

  20. Systems Analysis department. Annual progress report 1997

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Hans; Olsson, Charlotte; Petersen, Kurt E.

    1998-03-01

    The report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1997. The department is undertaking research within Energy systems Analysis, Integrated Energy, Environment and Development Planning - UNEP Centre, Industrial Safety and Reliability and Man/Machine Interaction. The report includes lists of publications lectures, committees and staff members. (au) 110 refs.

  1. Systems Analysis Department annual progress report 1999

    DEFF Research Database (Denmark)

    2000-01-01

    This report describes the work of the Systems Analysis Department at Risø National Laboratory during 1999. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning - UNEP Centre, Safety,Realiability and Human Factors, and Technology...

  2. Systems Analysis Department annual progress report 1998

    DEFF Research Database (Denmark)

    1999-01-01

    The report describes the work of the Systems Analysis Department at Risø National Laboratory during 1998. The department undertakes research within Energy Systems Analysis, Integrated Energy, Environment and Development Planning - UNEP Centre, IndustrialSafety and Reliability, Man/Machine Interac....../Machine Interaction, and Technology Scenarios. The report includes lists of publications, lectures, committees and staff members....

  3. Systems Analysis Department. Annual Report 2001

    Energy Technology Data Exchange (ETDEWEB)

    Duijm, N.J.; Jensen, E.; Larsen, H.; Skipper, S. (eds.)

    2002-04-01

    This report describes the work of the Systems Analysis Department at Risoe National Laboratory during 2001. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning - UNEP Centre, Safety, Reliability and Human Factors, and Technology Scenarios. The report includes summary statistics and lists of publications, committees and staff members. (au)

  4. Energy system analysis. Proceedings; Energiesystemanalyse. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Moest, Dominik [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (DE). Inst. fuer Technikfolgen-Abschaetzung und Systemanalyse (ITAS); Fichtner, Wolf; Grunwald, Armin (eds.) [Karlsruhe Univ. (T.H.) (Germany). Inst. fuer Industriebetriebslehre und Industrielle Produktion

    2009-07-01

    The proceedings on energy system analysis include the following contributions: energy system analysis in the KIT (Karlsruhe Institute of Technology) center energy; introduction energy system analysis; comparison of future energy - but how? models and scenarios - the scientific practice of energy system analysis; development of energy markets until 2050 - an overview on selected scenarios; system dynamics model of the German electricity market - model development and application in the company's practice; energy scenarios for megacities - concept and first results of the HGF project ''risk habitat megacity''; optimization of urban energy systems; agent-based simulation for market power measurement - an analysis for the German electricity market; study of the use of agent-based models for decentralized energy system simulation for the case of Guadeloupe; on the analysis of effects of fuel-dependent benchmarks of electricity generation costs and investment decisions in electric power industry; cost potential curves for on-shore wind power generation in the EU based on a geographic information system; straw and forest residues - results of a site analysis for the bioliq concept; consequential LCA (life cycle analysis) - a necessary development of LCA? - case discussion concerning lignocellulose-based bioethanol.

  5. Systems Analysis Department annual progress report 1998

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Hans; Olsson, Charlotte; Loevborg, Leif [eds.

    1999-03-01

    The report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1998. The department undertakes research within Energy Systems Analysis, Integrated Energy, Environment and Development Planning - UNEP Centre, Industrial Safety and Reliability, Man/Machine Interaction and Technology Scenarios. The report includes lists of publications, lectures, committees and staff members. (au) 111 refs.

  6. Types and concept analysis for legacy systems

    NARCIS (Netherlands)

    T. Kuipers (Tobias); L.M.F. Moonen (Leon)

    2000-01-01

    textabstractWe combine type inference and concept analysis in order to gain insight into legacy software systems. Type inference for Cobol yields the types for variables and program parameters. These types are used to perform mathematical concept analysis on legacy systems. We have developed

  7. Systems Analysis Department annual report 2001

    DEFF Research Database (Denmark)

    2002-01-01

    This report describes the work of the Systems Analysis Department at Risø National Laboratory during 2001. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning - UNEP Centre, Safety,Reliability and Human Factors, and Technology...

  8. Systems Analysis Department annual report 2003

    DEFF Research Database (Denmark)

    2004-01-01

    This report describes the work of the Systems Analysis Department at Risø National Laboratory during 2003. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning – UNEP Centre, Safety,Reliability and Human Factors, and Technology...

  9. Systems Analysis Department annual report 2002

    DEFF Research Database (Denmark)

    2003-01-01

    This report describes the work of the Systems Analysis Department at Risø National Laboratory during 2002. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning – UNEP Centre, Safety,Reliability and Human Factors, and Technology...

  10. Systems Analysis Department annual report 2000

    DEFF Research Database (Denmark)

    2001-01-01

    This report describes the work of the Systems Analysis Department at Risø National Laboratory during 2000. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning - UNEP Centre, Safety,Reliability and Human Factors, and Technology...

  11. Reliability analysis of flood defence systems

    NARCIS (Netherlands)

    Steenbergen, H.M.G.M.; Lassing, B.L.; Vrouwenvelder, A.C.W.M.; Waarts, P.H.

    2004-01-01

    In recent years an advanced program for the reliability analysis of flood defence systems has been under development. This paper describes the global data requirements for the application and the setup of the models. The analysis generates the probability of system failure and the contribution of

  12. Systems Analysis Department. Annual Report 2003

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, H.; Olsson, C. (eds.)

    2004-04-01

    This report describes the work of the Systems Analysis Department at Risoe National Laboratory during 2003. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning UNEP Centre, Safety, Reliability and Human Factors, and Technology Scenarios. The report includes summary statistics and list of staff members. (au)

  13. Systems Analysis Department. Annual Progress Report 1999

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Hans; Olsson, Charlotte; Loevborg, Leif [eds.

    2000-03-01

    This report describes the work of the Systems Analysis Department at Risoe National Laboratory during 1999. The department is undertaking research within Energy Systems Analysis, Energy, Environment and Development Planning-UNEP Centre, Safety, Reliability and Human Factors, and Technology Scenarios. The report includes summary statistics and lists of publications, committees and staff members. (au)

  14. a computer program for short circuit analysis of electric power systems

    African Journals Online (AJOL)

    ES Obe

    1981-03-01

    Mar 1, 1981 ... system. Specifically in short circuit studies, the power system network is subjected to postulated fault conditions and the resulting faulted network is solved to determine the phase (and sequence) voltages, currents and power of any bus or transmission line of the system. From this analysis, the power system.

  15. Doubly fed induction generator based wind turbine systems subject to recurring grid faults

    DEFF Research Database (Denmark)

    Chen, Wenjie; Blaabjerg, Frede; Zhu, Nan

    2014-01-01

    New grid codes demand the wind turbine systems to ride through recurring grid faults. In this paper, the performance of the Doubly Fed Induction Generator wind turbine system under recurring grid faults is analyzed. The stator natural flux produced by the voltage recovery after the first grid fault...

  16. Territory and place : Potential for analysis of political subjects' constitution: The case of an unemployed movement in Argentina

    Directory of Open Access Journals (Sweden)

    Fernanda Torres

    2011-01-01

    Full Text Available This paper aims at introducing the debate about the concepts of "space", "territory", "territoriality", "place" and their possible responsibility in the analysis of political subjects, especially in connection with an Argentine unemployment movement: the CTD Aníbal Verón. First of all, we deal with the debate about whether the space can be thought of as a political constituting dimensión or whether it is enough for it to be considered a conflict manifestation, limit demarcation and access control; the space built being understood as territory. Secondly, we also carry out an analysis of the relation between subjects and space, their appropriation and the meaning they give it, involving identity relations which are often analyzed through the category of place. Attention will be paid to two of the various practices which construct places [in terms of identity] in the territories built/appropriated by the organization: the neighborhood and the picket

  17. Non-cycloplegic spherical equivalent refraction in adults: comparison of the double-pass system, retinoscopy, subjective refraction and a table-mounted autorefractor.

    Science.gov (United States)

    Vilaseca, Meritxell; Arjona, Montserrat; Pujol, Jaume; Peris, Elvira; Martínez, Vanessa

    2013-01-01

    To evaluate the accuracy of spherical equivalent (SE) estimates of a double-pass system and to compare it with retinoscopy, subjective refraction and a table-mounted autorefractor. Non-cycloplegic refraction was performed on 125 eyes of 65 healthy adults (age 23.5±3.0 years) from October 2010 to January 2011 using retinoscopy, subjective refraction, autorefraction (Auto kerato-refractometer TOPCON KR-8100, Japan) and a double-pass system (Optical Quality Analysis System, OQAS, Visiometrics S.L., Spain). Nine consecutive measurements with the double-pass system were performed on a subgroup of 22 eyes to assess repeatability. To evaluate the trueness of the OQAS instrument, the SE laboratory bias between the double-pass system and the other techniques was calculated. The SE mean coefficient of repeatability obtained was 0.22D. Significant correlations could be established between the OQAS and the SE obtained with retinoscopy (r=0.956, Prefraction (r=0.955, Prefraction -0.23±0.50D; More myopic values were achieved by means of autorefraction 0.24±0.49D. The double-pass system provides accurate and reliable estimates of the SE that can be used for clinical studies. This technique can determine the correct focus position to assess the ocular optical quality. However, it has a relatively small measuring range in comparison with autorefractors (-8.00 to +5.00D), and requires prior information on the refractive state of the patient.

  18. Reachability Analysis of Probabilistic Systems

    DEFF Research Database (Denmark)

    D'Argenio, P. R.; Jeanett, B.; Jensen, Henrik Ejersbo

    2001-01-01

    than the original model, and may safely refute or accept the required property. Otherwise, the abstraction is refined and the process repeated. As the numerical analysis involved in settling the validity of the property is more costly than the refinement process, the method profits from applying...... such numerical analysis on smaller state spaces. The method is significantly enhanced by a number of novel strategies: a strategy for reducing the size of the numerical problems to be analyzed by identification of so-called {essential states}, and heuristic strategies for guiding the refinement process....

  19. Elastic-plastic behavior analysis for a flexible FOWT subjected to blade pitch control malfunction

    National Research Council Canada - National Science Library

    Srinivasamurthy, Sharath; Iijima, Kazuhiro; Fujikubo, Masahiko; Nihei, Yasunori

    2016-01-01

    Elastic-plastic behavior analysis methodology for a flexible FOWT is developed adopting a coupled simulation code which considers the flexibility of the floater and malfunction of blade pitch control...

  20. SUBJECTIVE CRITERIA OF SELF-ACTIVITY CONTROL OF THE RUSSIAN AND SLOVENIAN MANAGERS: COMPARATIVE ANALYSIS OF PROFESSIONAL COMPETENCE

    OpenAIRE

    E. Boštjančič; Ismagilova, F. S.; G. S. Miroljubova; N. Jansha

    2016-01-01

    Aim. The results of the first stage of the Russian-Slovenian crosscultural research are provided in the present article; the purpose is identification of the key factors that have an impact on the choice of control criteria of a management activity by the Russian and Slovenian leaders.Methods. Empirical information acquisition was made on the basis of the questionnaire «Subjective criteria of monitoring of activities performance» by G. Miroljubova and F. Ismagilova. The correlation analysis u...

  1. Operations Research/Systems Analysis.

    Science.gov (United States)

    1969-06-01

    weapons . 22. Non—military operations researc h has old management consulting j firms that had already clone time and motion studies in 1920 and analysis of...l building and solution that probably has mo re glamour than some of t h i - others is mathemati cal programming (see fig. 10) , whe re the re are

  2. Enhanced Decision Analysis Support System.

    Science.gov (United States)

    1981-03-01

    the types of "what if" questions can be both infinite in number and estremely difficult in soupleaity. However, two additional "what if" areas were...rigure 9). GRAPWICAL - The graphical representation of the analysis with the two estremes of the sensitivity Interval along the T-Aols and the volue

  3. Dynamic Response Analysis of Storage Cask Lid Structure Subjected to Lateral Impact Load of Aircraft Engine Crash

    Energy Technology Data Exchange (ETDEWEB)

    Almomania, Belal; Kang, Hyun Gook [KAIST, Daejeon (Korea, Republic of); Lee, Sanghoon [Keimyung Univ., Daegu (Korea, Republic of)

    2015-10-15

    Several numerical methods and tests have been carried out to measure the capability of storage cask to withstand extreme impact loads. Testing methods are often constrained by cost, and difficulty in preparation for several impact conditions with different applied loads, and areas of impact. Instead, analytic method is an acceptable process that can easily apply different impact conditions for the evaluation of cask integrity. The aircraft engine impact is considered as one of the most critical impact accidents on the storage cask that significantly affects onto the lid closure system and may cause a considerable release of radioactive materials. This paper presents a method for evaluating the dynamic responses of one upper metal cask lid closure without impact limiters subjected to lateral impact of an aircraft engine with respect to variation of the impact velocity. An assessment method to predict damage response due to the lateral engine impact onto metal storage cask has been studied by using computer code LS-DYNA. The dynamic behavior of the lid movements was successfully calculated by utilizing a simplified finite element cask model, which showed a good agreement with the previous research. The simulation analyses results showed that no significant plastic deformation for bolts, lid, and the cask body. In this study, the lid opening and sliding displacements are considered as the major factors in initiating the leakage path. This analysis may be useful for evaluating the instantaneous leakage rates in a connection with the sliding and opening displacements between the lid and the flange to ensure that the radiological consequences caused by an aircraft engine crash accident during the storage phase are within the permissible level.

  4. Adaptive Fuzzy Control for Uncertain Fractional-Order Financial Chaotic Systems Subjected to Input Saturation.

    Science.gov (United States)

    Wang, Chenhui

    2016-01-01

    In this paper, control of uncertain fractional-order financial chaotic system with input saturation and external disturbance is investigated. The unknown part of the input saturation as well as the system's unknown nonlinear function is approximated by a fuzzy logic system. To handle the fuzzy approximation error and the estimation error of the unknown upper bound of the external disturbance, fractional-order adaptation laws are constructed. Based on fractional Lyapunov stability theorem, an adaptive fuzzy controller is designed, and the asymptotical stability can be guaranteed. Finally, simulation studies are given to indicate the effectiveness of the proposed method.

  5. Adaptive Fuzzy Control for Uncertain Fractional-Order Financial Chaotic Systems Subjected to Input Saturation.

    Directory of Open Access Journals (Sweden)

    Chenhui Wang

    Full Text Available In this paper, control of uncertain fractional-order financial chaotic system with input saturation and external disturbance is investigated. The unknown part of the input saturation as well as the system's unknown nonlinear function is approximated by a fuzzy logic system. To handle the fuzzy approximation error and the estimation error of the unknown upper bound of the external disturbance, fractional-order adaptation laws are constructed. Based on fractional Lyapunov stability theorem, an adaptive fuzzy controller is designed, and the asymptotical stability can be guaranteed. Finally, simulation studies are given to indicate the effectiveness of the proposed method.

  6. Analyzing Brain Functions by Subject Classification of Functional Near-Infrared Spectroscopy Data Using Convolutional Neural Networks Analysis

    Directory of Open Access Journals (Sweden)

    Satoru Hiwa

    2016-01-01

    Full Text Available Functional near-infrared spectroscopy (fNIRS is suitable for noninvasive mapping of relative changes in regional cortical activity but is limited for quantitative comparisons among cortical sites, subjects, and populations. We have developed a convolutional neural network (CNN analysis method that learns feature vectors for accurate identification of group differences in fNIRS responses. In this study, subject gender was classified using CNN analysis of fNIRS data. fNIRS data were acquired from male and female subjects during a visual number memory task performed in a white noise environment because previous studies had revealed that the pattern of cortical blood flow during the task differed between males and females. A learned classifier accurately distinguished males from females based on distinct fNIRS signals from regions of interest (ROI including the inferior frontal gyrus and premotor areas that were identified by the learning algorithm. These cortical regions are associated with memory storage, attention, and task motor response. The accuracy of the classifier suggests stable gender-based differences in cerebral blood flow during this task. The proposed CNN analysis method can objectively identify ROIs using fNIRS time series data for machine learning to distinguish features between groups.

  7. Effects of mixing alcohol with caffeinated beverages on subjective intoxication: a systematic review and meta-analysis.

    Science.gov (United States)

    Benson, Sarah; Verster, Joris C; Alford, Chris; Scholey, Andrew

    2014-11-01

    It has been suggested that mixing alcohol with energy drinks or other caffeinated beverages may alter the awareness of (or 'mask') intoxication. The proposed reduction in subjective intoxication may have serious consequences by increasing the likelihood of engaging in potentially dangerous activities while intoxicated. A literature search was conducted to collect all studies measuring subjective intoxication after administration of alcohol with energy drinks, or with other caffeinated alcoholic drinks compared with alcohol alone. The studies were critically reviewed and, where possible, included in a meta-analysis in order to determine whether masking exists after mixing alcohol with caffeinated beverages. Sixteen articles were identified, of which nine could be used for the meta-analysis. When including the higher caffeine dose studies, the meta-analysis revealed no significant masking effect (p=0.404). Similarly, when including the lower caffeine dose studies, no significant masking effect was found (p=0.406). Despite the large range of caffeine doses (2.0-5.5 mg/kg resulting in absolute levels of 46-383 mg) and alcohol levels 0.29-1.068 g/kg (resulting in blood alcohol concentration (BAC) from 0.032 to 0.12%) investigated, caffeine had no effect on the judgement of subjective intoxication. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Analysis of an adhesively bonded single lap joint subjected to eccentric loading

    DEFF Research Database (Denmark)

    Anyfantis, Konstantinos; Tsouvalis, N. G.

    2013-01-01

    is benchmarking of computational tools. The test is based on a Single Lap Joint subjected to Eccentric Loading (SLJ-EL). The basic concept that lies behind this configuration is that the applied in-plane tensile load leads the adhesive layer to develop normal stresses, in-plane and out-of-plane shear stresses......A new experimental test is proposed, which allows the contribution of Mode I, II and III fracture modes to the failure of the adhesive layer of bonded joints aiming at achieving the realistic conditions often occurring during loading of practical joints. The main objective of this test......, which correspond to Mode I, II and III loading and fracture. These tests were designed so that the metal substrates do not enter plasticity and the adhesive achieves a mode mixity ratio between Mode II and Mode III not lower than 0.5. The experiments were simulated in a 3-dimensional finite element...

  9. Nonlinear Analysis and Scaling Laws for Noncircular Composite Structures Subjected to Combined Loads

    Science.gov (United States)

    Hilburger, Mark W.; Rose, Cheryl A.; Starnes, James H., Jr.

    2001-01-01

    Results from an analytical study of the response of a built-up, multi-cell noncircular composite structure subjected to combined internal pressure and mechanical loads are presented. Nondimensional parameters and scaling laws based on a first-order shear-deformation plate theory are derived for this noncircular composite structure. The scaling laws are used to design sub-scale structural models for predicting the structural response of a full-scale structure representative of a portion of a blended-wing-body transport aircraft. Because of the complexity of the full-scale structure, some of the similitude conditions are relaxed for the sub-scale structural models. Results from a systematic parametric study are used to determine the effects of relaxing selected similitude conditions on the sensitivity of the effectiveness of using the sub-scale structural model response characteristics for predicting the full-scale structure response characteristics.

  10. Morphological Analysis (SEM) of the Surface of a Non-Noble Dental Alloy Subjected to Electrocorrosion

    Science.gov (United States)

    Baciu, E. R.; Grădinaru, I.; Baciu, M.; Vasluianu, R. I.; Cimpoesu, R.; Baciu, C.; Bejinariu, C.

    2017-06-01

    Corrosion consists in the degradation of a material under the chemical or electrochemical action of the environment where it is placed. The investigations carried out aimed to show the structural modifications produced in Co-Cr-Mo alloy, Robur 400 (Eisenbacher Dental - Waren ED GmbH, Germany) subjected to electrocorrosion in Fusayama-Mayer artificial saliva. The specimens prepared by mechanical polishing were analysed structurally by using a scanning electron microscope. During the tests run we could notice a general corrosion of the surfaces of the specimens made from Robur alloy. Through 2D and 3D microscopy and qualitative determinations of the luminous variation we could notice the effects of electrocorrosion tests on the surface of the metal material.

  11. Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Mathias Baumert

    2014-12-01

    Full Text Available Autonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms. We recorded short-term ECG in 11 normal subjects during an experimental protocol that involved head-up tilt and mental arithmetic stress and computed sample entropy, cross-sample entropy and causal interactions based on conditional entropy from RR and QT interval time series. Head-up tilt resulted in a significant reduction in sample entropy of RR intervals and cross-sample entropy, while mental arithmetic stress resulted in a significant reduction in coupling directed from RR to QT. In conclusion, measures of entropy are suitable to detect changes in neural outflow to the heart and decoupling of repolarisation variability from heart rate variability elicited by orthostatic or mental arithmetic stress.

  12. Impact of Resistance Training in Subjects With COPD: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Liao, Wen-Hua; Chen, Jin-Wu; Chen, Xin; Lin, Lin; Yan, Hai-Yan; Zhou, Yu-Qi; Chen, Rui

    2015-08-01

    The goal of this study was to evaluate the effects of resistance training on subjects with COPD. We performed a systematic search in MEDLINE, PubMed, Embase, CINAHL, Elsevier ScienceDirect, EBM Reviews, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov and also of leading respiratory journals for randomized controlled trials on COPD treatment for ≥ 4 weeks with resistance training compared with non-exercise control or with combined resistance and endurance training compared with endurance training alone. Data from these studies were pooled to calculate odds ratio and weighted mean differences (WMDs) with 95% CI. Eighteen trials with 750 subjects with advanced COPD met the inclusion criteria. There were 2 primary and 5 secondary outcomes. Compared with non-exercise control, resistance training led to significant improvements in the dyspnea domain of the Chronic Respiratory Disease Questionnaire (WMD of 0.59, 95% CI 0.26-0.93, I2 = 0%, P < .001), skeletal muscle strength, and percent-of-predicted FEV1 (WMD of 6.88%, 95% CI 0.41-13.35%, I2 = 0%, P = .04). The combination of resistance and endurance training significantly improved the St George Respiratory Questionnaire total score (WMD of -7.44, 95% CI -12.62 to -2.25, I2 = 0%, P = .005), each domain score, and skeletal muscle strength. There were no significant differences in 6-min walk distance, 6-min pegboard and ring test, maximum exercise work load, and maximum oxygen consumption between the 2 groups. There were no reports of adverse events related to resistance-training intervention. Resistance training can be successfully performed alone or in conjunction with endurance training without increased adverse events during pulmonary rehabilitation in COPD. Copyright © 2015 by Daedalus Enterprises.

  13. Production Facility System Reliability Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Dale, Crystal Buchanan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Klein, Steven Karl [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-06

    This document describes the reliability, maintainability, and availability (RMA) modeling of the Los Alamos National Laboratory (LANL) design for the Closed Loop Helium Cooling System (CLHCS) planned for the NorthStar accelerator-based 99Mo production facility. The current analysis incorporates a conceptual helium recovery system, beam diagnostics, and prototype control system into the reliability analysis. The results from the 1000 hr blower test are addressed.

  14. Environmental systems analysis of pig production

    OpenAIRE

    Strid Eriksson, Ingrid

    2004-01-01

    The aim of this thesis was to develop the SALSA models (Systems AnaLysis for Sustainable Agriculture), and to apply them to studies for the benefit of more sustainable pig production. Within the framework of environmental systems analysis, the SALSA models were constructed as substance and energy flow models using life cycle assessment methodology for impact assessment and scope definition. The pig production system studied included rearing of growing-finishing pigs (SALSA-pig model) and prod...

  15. [Comparative analysis of the glycemic response and glycemic index of instant mashed potatoes in subjects undergoing laparoscopic sleeve gastrectomy and control subjects].

    Science.gov (United States)

    Fuentes Valdes, Gabriel; del Valle Flores, Miguel; Vega Soto, Claudia

    2014-12-01

    The laparoscopic sleeve gastrectomy (LSG) is a successful surgical procedure for morbid obesity. However, post surgery weight regain is usual, thus applying the glycemic index could promote good weight control. To compare the glycemic index (GI) and glycemic response (GR) obtained of instant mashed potatoes in individuals subjected to LSG versus control subjects. GI and GR were assessed in 10 LSG subjects and compared with 10 controls. GI methodology proposed by FAO/WHO was used; instant mashed potatoes as test food and white bread as standard food (50g available CHO). Capillary blood sample 0 (fasting), 30, 60, 90 and 120 minutes. The GI was determined by trapezoidal method. ANOVA was used to compare a factor between RG and IG groups; t-student to compare RG between foods. Statistical significance pglycemic responses in LSG group, and its consumption possibly favoring weight regain. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  16. Analysis of streaming media systems

    NARCIS (Netherlands)

    Lu, Y.

    2010-01-01

    Multimedia services have been popping up at tremendous speed in recent years. A large number of these multimedia streaming systems are introduced to the consumer market. Internet Service Providers, Telecommunications Operators, Service/Content Providers, and end users are interested in the

  17. Distribution system analysis and automation

    CERN Document Server

    Gers, Juan

    2013-01-01

    A comprehensive guide to techniques that allow engineers to simulate, analyse and optimise power distribution systems which combined with automation, underpin the emerging concept of the "smart grid". This book is supported by theoretical concepts with real-world applications and MATLAB exercises.

  18. Observer Design for One-Sided Lipschitz Nonlinear Systems Subject to Measurement Delays

    Directory of Open Access Journals (Sweden)

    Sohaira Ahmad

    2015-01-01

    Full Text Available This paper presents a novel nonlinear observer-design approach to one-sided Lipschitz nonlinear systems in the presence of output delays. The crux of the approach is to overcome the practical consequences of time delays, encountered due to distant sensor position and time lag in measurement, for estimation of physical and engineering nonlinear system states. A Lyapunov-Krasovskii functional is employed, the time derivative of which is solved using Jensen’s inequality, one-sided Lipschitz condition, and quadratic inner-boundedness, and, accordingly, design conditions for delay-range-dependent nonlinear observer for delayed one-sided Lipschitz systems are derived. Further, novel solutions to the problems of delay-dependent observer synthesis of one-sided Lipschitz models and delay-range-dependent state estimation of linear and Lipschitz nonlinear systems are deduced from the present delay-range-dependent technique. An observer formulation methodology for retrieval of one-sided Lipschitz nonlinear-system states, which is robust against L2 norm-bounded perturbations, is devised. The resultant design conditions, in contrast to the conventional procedures, can be solved via less conservative linear matrix inequality- (LMI- based routines that succeed by virtue of additional LMI variables, meaningful transformations, and cone complementary linearization algorithm. Numerical examples are worked out to illustrate the effectiveness of the proposed observer-synthesis approach for delayed one-sided Lipschitz systems.

  19. Incidence of atrial fibrillation is associated with age and gender in subjects practicing physical exercise: A meta-analysis and meta-regression analysis.

    Science.gov (United States)

    Brunetti, Natale Daniele; Santoro, Francesco; Correale, Michele; De Gennaro, Luisa; Conte, Giusy; Di Biase, Matteo

    2016-10-15

    The link between physical activity and the risk of atrial fibrillation (AF) remains controversial. We therefore sought to further assess by a meta-analysis whether increased levels of physical activity may increase the risk of AF. In October 2015, a PubMed research was conducted for studies that investigated this topic. We identified 11 relevant studies with a total of 81,787 participants. The pooled analysis did not show an increased risk of AF in subjects practicing physical activity (odds ratio (OR)=0.92, 95% C.I.=0.84-1.01, p=0.077, I(2)=90%). However, given the observed large heterogeneity among studies, a subgroup analysis was performed in order to identify possible variables influencing the risk of AF. Significantly higher risk of AF in subjects with reported physical activity was found in studies enrolling exclusively male participants (OR=7.49, 95% C.I.=3.12-19.01, pmeta-regression analysis between age and OR of AF (p=0.047). In conclusion, in our meta-analysis, there is a non-significant trend toward lower risk of AF in subjects practicing physical activity. The risk seems higher in male subjects. A reverse correlation between age and risk of AF seems to be evident. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  20. NONLINEAR ANALYSIS OF CFRP- PRESTRESSED CONCRETE BEAMS SUBJECTED TO INCREMENTAL STATIC LOADING BY FINITE ELEMENTS

    Directory of Open Access Journals (Sweden)

    Husain M. Husain

    2013-05-01

    Full Text Available In this work a program is developed to carry out the nonlinear analysis (material nonlinearity of prestressed concrete beams using tendons of carbon fiber reinforced polymer (CFRP instead of steel. The properties of this material include high strength, light weight, and insusceptibility to corrosion and magnetism. This material is still under investigation, therefore it needs continuous work to make it beneficial in concrete design. Four beams which are tested experimentally by Yan et al. are examined by the developed computer program to reach a certain analytical approach of the design and analysis of such beams because there is no available restrictions or recommendations covering this material in the codes. The program uses the finite element analysis by dividing the beams into isoparametric 20-noded brick elements. The results obtained are good in comparison with experimental results.

  1. Requirement analysis for autonomous systems and intelligent ...

    African Journals Online (AJOL)

    user

    degree in computer science and and an M.Sc degree in Artificial Intelligence from Blekinge Institute of Technology Karlskrona, Sweden in 2003 and 2007 respectively. His research interests are intelligent systems applications to power system, power system analysis and distributed control. Morten Lind is Professor of ...

  2. An Effective Distributed Model for Power System Transient Stability Analysis

    Directory of Open Access Journals (Sweden)

    MUTHU, B. M.

    2011-08-01

    Full Text Available The modern power systems consist of many interconnected synchronous generators having different inertia constants, connected with large transmission network and ever increasing demand for power exchange. The size of the power system grows exponentially due to increase in power demand. The data required for various power system applications have been stored in different formats in a heterogeneous environment. The power system applications themselves have been developed and deployed in different platforms and language paradigms. Interoperability between power system applications becomes a major issue because of the heterogeneous nature. The main aim of the paper is to develop a generalized distributed model for carrying out power system stability analysis. The more flexible and loosely coupled JAX-RPC model has been developed for representing transient stability analysis in large interconnected power systems. The proposed model includes Pre-Fault, During-Fault, Post-Fault and Swing Curve services which are accessible to the remote power system clients when the system is subjected to large disturbances. A generalized XML based model for data representation has also been proposed for exchanging data in order to enhance the interoperability between legacy power system applications. The performance measure, Round Trip Time (RTT is estimated for different power systems using the proposed JAX-RPC model and compared with the results obtained using traditional client-server and Java RMI models.

  3. Motion planning of mobile multi-limb robotic systems subject to force and friction constraints

    Science.gov (United States)

    Madhani, Akhil; Dubowsky, Steven

    1992-01-01

    A method is presented to generate motions for a class of multilimb robotic systems enabling them to apply large static forces over large ranges of motion without saturating actuator effort limits, system-environment friction constraints, kinematic joint limits, or geometric workspace obstacles. The approach, termed the force-workspace (FW) approach, maps these constraints into the system C-space to form constraint obstacles using a recursive subdivision process. To generate motions along which actuator efforts can be specified without violating system constraints, paths are planned that avoid these constraint obstacles. The method permits the shape of the paths to be controlled using any configuration-dependent performance criterion. The FW approach was applied to a proposed three-limb planar climbing robot whose task is to climb upwards between two vertical walls by pushing outwards to generate frictional support. Motions were planned automatically within the system FW, enabling it to lift itself upwards using two limbs at a time, and a gait was planned to enable it to switch limbs and climb continuously.

  4. Receiver System Analysis and Optimization

    Science.gov (United States)

    2013-01-01

    for several devices from the IBM SiGe 8HP process design kit (the manufacturing process used for the MDREX project): bipolar transistor ( BJT ), spiral...of the project. Most significantly, a transistor -level simulation algorithm compatible with the system level simulation algorithm was developed. This... transistor -level simulation program simultaneously and synchronizing them at time intervals. Since the new capability allows the simulation of the entire

  5. VISION 21 SYSTEMS ANALYSIS METHODOLOGIES

    Energy Technology Data Exchange (ETDEWEB)

    G.S. Samuelsen; A. Rao; F. Robson; B. Washom

    2003-08-11

    Under the sponsorship of the U.S. Department of Energy/National Energy Technology Laboratory, a multi-disciplinary team led by the Advanced Power and Energy Program of the University of California at Irvine is defining the system engineering issues associated with the integration of key components and subsystems into power plant systems that meet performance and emission goals of the Vision 21 program. The study efforts have narrowed down the myriad of fuel processing, power generation, and emission control technologies to selected scenarios that identify those combinations having the potential to achieve the Vision 21 program goals of high efficiency and minimized environmental impact while using fossil fuels. The technology levels considered are based on projected technical and manufacturing advances being made in industry and on advances identified in current and future government supported research. Included in these advanced systems are solid oxide fuel cells and advanced cycle gas turbines. The results of this investigation will serve as a guide for the U. S. Department of Energy in identifying the research areas and technologies that warrant further support.

  6. A Meta-Analysis of Single Subject Design Writing Intervention Research

    Science.gov (United States)

    Rogers, Leslie Ann; Graham, Steve

    2008-01-01

    There is considerable concern that students do not develop the writing skills needed for school, occupational, or personal success. A frequent explanation for this is that schools do not do a good job of teaching this complex skill. A recent meta-analysis of true- and quasi-experimental writing intervention research (S. Graham & D. Perin,…

  7. Analysis and categorization of information sources in the subject field of cynology

    OpenAIRE

    Bušková, Markéta

    2015-01-01

    The aim of this bachelor thesis, titled "Analysis and Categorization of Information Sources for the Field of Dog-breeding", is to map and analyze information sources relating to the field of dog-breeding, introduce dog-breeding as a field, compile an overview of current information sources for this field and focus on particularly defined groups of information sources.

  8. Analysis of Students Attrition in the Sciences Subjects Areas in Ambrose Alli University, Ekpoma

    Science.gov (United States)

    Olusi, F. I.; Akahomen, D. O.; Otete, C. O.

    2013-01-01

    The study, analysis of student's attrition in Ambrose Alli University (AAU) Ekpoma Nigeria was carried out to determine the exact number of students who attrite from selected faculties of the university. The study employed the descriptive survey design. Three hypotheses were stated and tested. On the hypothesis which tested the general attrition…

  9. Youth Development as Subjectified Subjectivity – a Dialectical-Ecological Model of Analysis

    DEFF Research Database (Denmark)

    Pedersen, Sofie; Bang, Jytte

    2016-01-01

    school, we carry out an analysis of a 16-year old high school student and how her approach to beer, to beer drinking as a part of Danish high school life-style, and to herself changes over time. We suggest a dialectical-ecological model to analyze the dialectical and synthetic movements over time...

  10. Improving Treatment Plan Implementation in Schools: A Meta-Analysis of Single Subject Design Studies

    Science.gov (United States)

    Noell, George H.; Gansle, Kristin A.; Mevers, Joanna Lomas; Knox, R. Maria; Mintz, Joslyn Cynkus; Dahir, Amanda

    2014-01-01

    Twenty-nine peer-reviewed journal articles that analyzed intervention implementation in schools using single-case experimental designs were meta-analyzed. These studies reported 171 separate data paths and provided 3,991 data points. The meta-analysis was accomplished by fitting data extracted from graphs in mixed linear growth models. This…

  11. Differences in Pre and Post Vascular Patterning of Retinas from ISS Crew Members and HDT Subjects by VESGEN Analysis

    Science.gov (United States)

    Murray, M. C.; Vizzeri, G.; Taibbi, G.; Mason, S. S.; Young, M. H.; Zanello, S. B.; Parsons-Wingerter, P. A.

    2018-01-01

    Accelerated research by NASA [1] has investigated the significant risks for visual and ocular impairments Spaceflight Associated Neuro-Ocular Syndrome /Visual Impairment/Intracranial Pressure (SANS/VIIP) incurred by microgravity spaceflight, especially long-duration missions. Our study investigates the role of blood vessels in the incidence and etiology of SANS/VIIP within the retinas of Astronaut crewmembers pre-and post-flight to the International Space Station (ISS) by NASA's VESsel GENeration Analysis (VESGEN). The response of retinal vessels in crewmembers to microgravity was compared to that of retinal vessels to Head-Down Tilt (HDT) in subjects undergoing 70-Day Bed Rest. The study tests the proposed hypothesis that cephalad fluid shifts missions, resulting in ocular and visual impairments, are necessarily mediated in part by retinal blood vessels, and are therefore accompanied by significant remodeling of retinal vasculature.Vascular patterns in the retinas of crew members and HDTBR subjects extracted from 30° infrared (IR) Heidelberg Spectralis® images collected pre/postflight and pre/post HDTBR, respectively, were analyzed by VESGEN (patent pending). a mature, automated software developed as a research discovery tool for progressive vascular diseases in the retina and other tissues [2]. The weighted, multi-parametric VESGEN analysis generates maps of branching arterial and venous trees and quantification by parameters such as the fractal dimension (Df, a modern measure of vascular space-filling capacity), vessel diameters, and densities of vessel length and number classified into specific branching generations by vascular physiological branching rules [2,3]. The retrospective study approved by NASA’s Institutional Review Board included six HDT subjects (NASA Flight Analogs Research Unit [FARU] Campaign 11; for example, [4]) and eight ISS crewmembers monitored by routine occupational surveillance who provided their study consents to NASA’s Lifetime

  12. Stabilization of ODE-Schrodinger cascaded systems subject to boundary control matched disturbance

    Directory of Open Access Journals (Sweden)

    Ya-Ping Guo

    2015-09-01

    Full Text Available In this article, we consider the state feedback stabilization of ODE-Schrodinger cascaded systems with the external disturbance. We use the backstepping transformation to handle the unstable part of the ODE, then design a feedback control which is used to cope with the disturbance and stabilize the Schrodinger part. By active disturbance rejection control (ADRC approach, the disturbance is estimated by a constant high gain estimator, then the feedback control law can be designed. Next, we show that the resulting closed-loop system is practical stable, where the peaking value appears in the initial stage and the stabilized result requires that the derivative of disturbance be uniformly bounded. To avoid the peak phenomenon and to relax the restriction on the disturbance, a time varying high gain estimator is presented and asymptotical stabilization of the corresponding closed-loop system is proved. Finally, the effectiveness of the proposed control is verified by numerical simulations.

  13. Tract Orientation and Angular Dispersion Deviation Indicator (TOADDI): A framework for single-subject analysis in diffusion tensor imaging.

    Science.gov (United States)

    Koay, Cheng Guan; Yeh, Ping-Hong; Ollinger, John M; İrfanoğlu, M Okan; Pierpaoli, Carlo; Basser, Peter J; Oakes, Terrence R; Riedy, Gerard

    2016-02-01

    The purpose of this work is to develop a framework for single-subject analysis of diffusion tensor imaging (DTI) data. This framework is termed Tract Orientation and Angular Dispersion Deviation Indicator (TOADDI) because it is capable of testing whether an individual tract as represented by the major eigenvector of the diffusion tensor and its corresponding angular dispersion are significantly different from a group of tracts on a voxel-by-voxel basis. This work develops two complementary statistical tests based on the elliptical cone of uncertainty, which is a model of uncertainty or dispersion of the major eigenvector of the diffusion tensor. The orientation deviation test examines whether the major eigenvector from a single subject is within the average elliptical cone of uncertainty formed by a collection of elliptical cones of uncertainty. The shape deviation test is based on the two-tailed Wilcoxon-Mann-Whitney two-sample test between the normalized shape measures (area and circumference) of the elliptical cones of uncertainty of the single subject against a group of controls. The False Discovery Rate (FDR) and False Non-discovery Rate (FNR) were incorporated in the orientation deviation test. The shape deviation test uses FDR only. TOADDI was found to be numerically accurate and statistically effective. Clinical data from two Traumatic Brain Injury (TBI) patients and one non-TBI subject were tested against the data obtained from a group of 45 non-TBI controls to illustrate the application of the proposed framework in single-subject analysis. The frontal portion of the superior longitudinal fasciculus seemed to be implicated in both tests (orientation and shape) as significantly different from that of the control group. The TBI patients and the single non-TBI subject were well separated under the shape deviation test at the chosen FDR level of 0.0005. TOADDI is a simple but novel geometrically based statistical framework for analyzing DTI data. TOADDI may be

  14. Do subjective cognitive complaints correlate with cognitive impairment in systemic lupus erythematosus? A Danish outpatient study

    DEFF Research Database (Denmark)

    Vogel, A; Bhattacharya, S; Larsen, J L

    2011-01-01

    This study examined the prevalence of cognitive impairment and its association with depressive symptoms and self-reported cognitive complaints in Danish outpatients with systemic lupus erythematosus (SLE). Fifty-seven consecutive female SLE-outpatients were examined with a comprehensive neuropsyc......This study examined the prevalence of cognitive impairment and its association with depressive symptoms and self-reported cognitive complaints in Danish outpatients with systemic lupus erythematosus (SLE). Fifty-seven consecutive female SLE-outpatients were examined with a comprehensive...

  15. Spatial aspects of sound quality - and by multichannel systems subjective assessment of sound reproduced by stereo

    DEFF Research Database (Denmark)

    Choisel, Sylvain

    The reproduction of sound by stereo and by multichannel systems is affected by many factors which will give rise to various complex sensations in listeners, and thereby influence the perceived overall quality. In this Ph.D. thesis, the perceptual changes associated with different reproduction...... on the perceived direction of panned sources. The second part of the thesis addresses the identification of auditory attributes which play a role in the perception of sound reproduced by multichannel systems. Short musical excerpts were presented in mono, stereo and several multichannel formats to evoke various...

  16. Automation of Methods for the Subjective Measuring of Factors in the Operation of Automated Information Systems by Means of VBA

    Directory of Open Access Journals (Sweden)

    Lyudmila V. Gorbatova

    2015-01-01

    Full Text Available This article describes the process of assessing the effectiveness of the operation of automated information systems in colleges using the method of pairwise comparison and discusses numerical representations used with the above method. The author lists methods for the subjective measuring of the effective operation of automated information systems. The article proposes a way to automate the methods that makes it possible to simplify performing calculations and reduce the amount of time it takes to determine the outcome of a specific task. The author provides an algorithm with the results of work carried out.

  17. Analysis of Risks and Factors of Formation of the Structure of Financial Capital of Subject of Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Rubaha Mariya V.

    2013-11-01

    Full Text Available The article is devoted to analysis of the structure of sources of financing economic subjects, study of commercial and financial risks of formation of the structure of financial capital of subjects of entrepreneurship. The article pays significant attention to calculation of the weighted average cost of capital, degrees of financial and operational leverages and also to assessment of their mutual influence upon results of financial and economic activity of an enterprise. It studies impact of factors of external environment on the structure of sources of financing subjects of entrepreneurship, these factors include specific features of operational activity, quality and liquidity of assets, concentration of own capital, stages of the life cycle, level of profitability of operational activity, credit history of a borrower and a necessity to ensure the prospective repayment capacity, and financial mentality of owners and managers of an enterprise. The article also analyses factors of external environment of an enterprise (cost of attraction of financing from different sources, commodity and financial markets situations, state regulation and control over business processes, level of taxation of profit of enterprises and also income of physical persons and legal entities – investors from owning securities that influence the possibilities to attract financial capital and, consequently, prospects of efficient functioning of a subject of entrepreneurship in a long-term prospect.

  18. Development of an Analysis System for Low Voltage Distribution System

    Science.gov (United States)

    Matsuda, Katsuhiro; Wada, Masaru; Hirano, Shinichiro; Hirai, Yoshihiro; Tsuboe, Yasuhiro; Watanabe, Masahiro; Furukawa, Toshiyuki

    In recent years, distributed resources such as photovoltaic power generation system or wind-turbine generator system are increased, therefore the distributed resources which connect to distribution networks are increased gradually. Under the situation there are several problems such as expansion of the voltage fluctuation, increase of the short circuit current, increase of harmonics phenomenon which we have to consider, and the problems make us difficult to examine the effect of interconnection and to design the distribution system. However, analysis support system to evaluate the influence to connect distributed resources to low voltage distribution system has not developed. Therefore We have developed the analysis system for low voltage for low voltage distribution systems. We can evaluate the influence of distributed resources accurately, examine the interconnection and design the configuration of distribution networks by using the analysis system. In this paper, the concept of the analysis system, the load flow method for unbalanced V-connection 3-phase 4-line distribution system and the calculation method for the connectable capacity of distributed resources. Outline of the man/machine interface and examples of calculation results for sample network are also described.

  19. ANALYSIS OF NON-CIRCULAR MEMBERS SUBJECTED TO TWISTING LOADS: A FINITE DIFFERENCE APPROACH

    Directory of Open Access Journals (Sweden)

    Chaitanya Goteti

    2015-09-01

    Full Text Available Abstract Many torque carrying members have circular sections such as shafts. However, there are certain structural members like automotive chassis frames, cross members and machine frames which are often subjected to twisting loads and their cross sections are non circular. several methods were developed to analyze such sections such as Saint Venant’s semi inverse method, Prandtl’s elastic membrane analogy...etc. In this paper, the second order partial differential stress function equation for non-circular torsional members is applied on a rectangular section for different b/h (height /width of section values and the solutions for maximum torsional shear stress are found by employing second order finite difference method. The results are compared to the results obtained from commercial finite element software (ANSYS 10 and by direct solution of the stress function equation using analytical correlations available for rectangular sections. The results obtained by different approaches are in close congruence with a percentage deviation of only 3.22. It is observed that, in implementing second order finite difference scheme, the error in estimating stress is proportional to S2. Where “S” is the grid size.   Keywords: Non-Circular Section, Prandtl’s stress function, Finite difference scheme, Grid size

  20. Estimation of spinopelvic muscles' volumes in young asymptomatic subjects: a quantitative analysis.

    Science.gov (United States)

    Amabile, Celia; Moal, Bertrand; Chtara, Oussama Arous; Pillet, Helene; Raya, Jose G; Iannessi, Antoine; Skalli, Wafa; Lafage, Virginie; Bronsard, Nicolas

    2017-04-01

    Muscles have been proved to be a major component in postural regulation during pathological evolution or aging. Particularly, spinopelvic muscles are recruited for compensatory mechanisms such as pelvic retroversion, or knee flexion. Change in muscles' volume could, therefore, be a marker of greater postural degradation. Yet, it is difficult to interpret spinopelvic muscular degradation as there are few reported values for young asymptomatic adults to compare to. The objective was to provide such reference values on spinopelvic muscles. A model predicting the muscular volume from reduced set of MRI segmented images was investigated. A total of 23 asymptomatic subjects younger than 24 years old underwent an MRI acquisition from T12 to the knee. Spinopelvic muscles were segmented to obtain an accurate 3D reconstruction, allowing precise computation of muscle's volume. A model computing the volume of muscular groups from less than six MRI segmented slices was investigated. Baseline values have been reported in tables. For all muscles, invariance was found for the shape factor [ratio of volume over (area times length): SD muscles' values for a reference population have been reported. A new model predicting the muscles' volumes from a reduced set of MRI slices is proposed. While this model still needs to be validated on other populations, the current study appears promising for clinical use to determine, quantitatively, the muscular degradation.