WorldWideScience

Sample records for subject reading level

  1. Reading comprehension levels in scholars.

    Science.gov (United States)

    Carvalho, Carolina Alves Ferreira de; Avila, Clara Regina Brandão de; Chiari, Brasília Maria

    2009-01-01

    important reading performance measurements are related to how and to what extent a child understands a written text. to study the performance of primary school (Ensino Fundamental) students in reading comprehension tasks according to the variables grade and type of school. 160 students from the 3rd to the 6th grades were screened and later evaluated based on the retelling and question answering about a given text. students of the 5th and 6th grades of private schools presented a better performance on issues related to implicit information when compared to students of public schools. The overall analysis of the educational level revealed, through the retelling task, a better performance of the 6th grade students in terms of the number of present macro propositions and a low performance of the 5th grade students in terms of the achieved comprehension level, in both types of school. When answering text-derived questions, the 4th, 5th and 6th grade students performed better than the 3rd grade students regarding explicit questions. When considering implicit questions, the 4th grade students performed better than all the other grades, in both types of school. These results gave evidence to the influence of the different texts used in each grade. the 5th and 6th grades from private schools were the only grades that performed better when compared to public schools in general, regarding answering implicit knowledge questions. All students achieved some level of reading comprehension.

  2. Prestige Factors Influencing Evaluative Level Reading.

    Science.gov (United States)

    Johnson, Linda L.

    Prestige-suggestion, the effect that the prestige or reputation of a source has on a receiver, is the subject of this paper. Three research studies which have been done recently by researchers in reading are reported. These studies asked the following questions: If consumers evaluate products by means of reading store advertisements, will they be…

  3. Normal movement reading in Asperger subjects.

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    Avikainen, S; Kulomäki, T; Hari, R

    1999-11-26

    Patients with autism and Asperger syndrome (AS) are impaired in mindreading and imitation skills. One possibility would be that their 'mirror neuron' system, which matches action execution and observation, does not function properly. To test this hypothesis we compared action-viewing related motor cortex functions in an AS group (one autistic and four AS subjects) and eight control subjects. In both groups viewing hand actions modified the neuromagnetic approximately 20 Hz oscillatory activity in the primary motor cortex to the same extent. Thus impaired mindreading and imitation skills found in AS and autism do not seem to result from dysfunction of the motor cortex part of the action execution/observation system.

  4. Impact of the Reading Buddies Program on Reading Level and Attitude Towards Reading

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    Hayley Dolman

    2013-03-01

    Full Text Available Objective – This research examines the Reading Buddies program at the Grande Prairie Public Library, which took place in July and August of 2011 and 2012. The Reading Buddies program pairs lower elementary students with teen volunteers for reading practice over the summer. The aim of the study was to discover how much impact the program would have on participating children’s reading levels and attitudes towards reading.Methods – During the first and last sessions of the Reading Buddies program, the participants completed the Elementary Reading Attitudes Survey (ERAS and the Graded Word Recognition Lists from the Bader Reading and Language Inventory (6th ed., 2008.Participants were also asked for their grade and sex, and the program coordinator kept track of attendance. Results – There were 37 Reading Buddies participants who completed both the pre- and post-tests for the study. On average, the program had a small positive effect on participants’ reading levels and a small negative effect on their attitudes towards reading. There was a larger range of changes to the ERAS scores than to the reading test scores, but most participants’ scores did not change dramatically on either measure.Conclusions – Although findings are limited by the small size of the data-set, results indicate that many of the Reading Buddies participants maintained their reading level over the summer and had a similar attitude towards reading at the end of the program. On average, reading levels increased slightly and attitudes towards reading were slightly more negative. Many factors could not be taken into account during the study (e.g., the amount of reading done at home. A study with a control group that did not participate in the program could help to assess whether the program helped to combat summer learning loss.

  5. The Relationship between Reading Self-Efficacy Beliefs, Reading Strategy Use and Reading Comprehension Level of Iranian EFL Learners

    Science.gov (United States)

    Naseri, Mahdieh; Zaferanieh, Elaheh

    2012-01-01

    This co-relational study explored the relationship between reading self-efficacy beliefs, reading strategies use and reading comprehension level of Iranian EFL learners. In this study, Michigan reading comprehension test, a self-reported Reading Strategy Use Questionnaire, and a Reading Self-efficacy Questionnaire were administered to eighty…

  6. Oral Reading Fluency as a Predictor of Silent Reading Fluency at Secondary and Postsecondary Levels

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    Seok, Soonhwa; DaCosta, Boaventura

    2014-01-01

    This research investigated oral reading fluency as a predictor of silent reading fluency at the secondary and postsecondary levels. Several measures were used, including the Gray Oral Reading Test, the Test of Silent Word Reading Fluency, the Test of Silent Contextual Reading Fluency, and the Reading Observation Scale. A total of 223 students…

  7. Lip-reading abilities in a subject with congenital prosopagnosia.

    Science.gov (United States)

    Wathour, J; Decat, M; Vander Linden, F; Deggouj, N

    2015-01-01

    We present the case of an individual with congenital prosopagnosia or "face blindness", a disorder where the ability to recognize faces is impaired. We studied the lip-reading ability and audiovisual perception of this subject using a DVD with four conditions (audiovisual congruent, auditory, visual, and audiovisual incongruent) and compared results with a normal patient cohort. The patient had no correct responses in the visual lip-reading task; whereas, he improved in the audiovisual congruent task. In the audiovisual incongruent task, the patient provided one response; thus, he was able to lip-read. (He was able to use lip-reading/to use labial informations) This patient perceived only global dynamic facial movements, not the fine ones. He had a sufficient complementary use of lip-reading in audiovisual tasks, but not visual ones. These data are consistent with abnormal development of the pathways used for visual speech perception and associated with second-order face processing disorders and normal development of the audiovisual network for speech perception.

  8. Thinking and Reading for Entry Level Workers.

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    Allentown Literacy Council, PA.

    A pilot project demonstrated that cooperative training programs are effective and cost efficient for small businesses. Common entry-level reading and thinking tasks were identified in a variety of occupational areas. Five growing occupational areas were identified: industrial/machine operator; health care; food preparation; hotel/hospitality; and…

  9. Comparison of Reading Levels of Pharmacy Students and Reading Level of Primary Literature

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    Cathy H Ficzere

    2016-09-01

    Full Text Available Objectives: The project purpose was to evaluate pharmacy students’ reading levels using the Nelson-Denney Reading Test (NDRT and compare these results with the reading level of primary literature to investigate incongruities between student’s comprehension ability and the readability level of assigned reading in the curriculum. Methods: The NDRT was administered to first- through third-year student pharmacists to determine grade equivalents (GE for vocabulary and reading comprehension. Twenty articles previously identified as Patient-Oriented Evidence that Matters (POEMs were analyzed to determine the Flesch-Kincaid Grade Level and Gunning-Fog Score. Student demographics, information regarding language spoken, and reading habits, were also assessed. Pearson product moment correlations, t-tests, ANOVA, and descriptive statistics were used to assess relationships between demographic data and NDRT scores. Results: One hundred students participated. The mean NDRT total grade equivalent (±SD was 16.95 ± 2.1 (median = 17.3. NDRT grade equivalents were statistically different for students with different racial or ethnic backgrounds (t(98=3.74, p=0.026, English as a second language (ESL students (t(98=5.19, p=0.021, and students that read works of fiction for pleasure (t(98=4.31, p=0.002. The average Gunning-Fog Score for all primary literature articles was 11.48, with the introduction section being the most complex. The average Flesch-Kincaid Grade Level was 17.04, with the results section scoring the lowest average grade level. Implications: While the overall reading grade level of our pharmacy students suggests that they are capable of comprehending reading assigned in the pharmacy curriculum, minority students and students for whom English is a second language may struggle with comprehending complex text. Conflict of Interest We declare no conflicts of interest or financial interests that the authors or members of their immediate families have

  10. The Relation of Word Reading Fluency Initial Level and Gains with Reading Outcomes

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    Smith, Jean Louise M.; Cummings, Kelli D.; Nese, Joseph F. T.; Alonzo, Julie; Fien, Hank; Baker, Scott K.

    2014-01-01

    The purpose of this research brief is to present results from a study investigating the relation between word reading fluency (both initial level and fall-winter gain scores), passage reading fluency, and reading comprehension. Word reading fluency data were collected in the fall and winter; outcome measures were administered in the spring of…

  11. Home readings of blood pressure in assessment of hypertensive subjects

    DEFF Research Database (Denmark)

    Nielsen, P.E.; Myschetzky, P; Andersen, A R

    1986-01-01

    Out-patient clinic blood pressure (OPC-BP) was compared to home blood pressure (Home-BP) measured three times daily during a two week period in 122 consecutively referred hypertensive subjects. A semi-automatic device (TM-101) including a microphone for detection of Korotkoff-sounds, self......-deflation of cuff pressure and digital display of blood pressure was used. Mean difference between OPC-BP and Home-BP was systolic +13 mm Hg (range -21 - +100 mg Hg) and diastolic +5 mm Hg (range -27 - +36 mm Hg). Although a significant correlation could be demonstrated between Home-BP and OPC-BP, the inter......-individual scatter was pronounced and unpredictable from the hypertensive organ damages. It is argued, that home readings should be used to greater extent in the evaluation of patients with hypertension....

  12. Assessing the relationship between Vocabulary Level Test (VLT and reading comprehension

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    Alpino Susanto

    2017-09-01

    Full Text Available It has been considered crucial about how vocabulary knowledge in relation with reading comprehension. This research was conducted to explore the link of Indonesian students Vocabulary Level Test (VLT performance and their reading textbook on reading subject. Through this pilot research, it can describe the implications profile in English teaching process especially in reading. Furthermore it can give more information in how to measure the reading textbook reference for reading subject or other similar subject that involve reading activities. There were 30 undergraduate students in Universitas Putera Batam that participated in the VLT. Their English textbook (Mosaic 1 was profiled to measure the lexical vocabulary level. The results indicated that only 1% of the participants had mastered the 2000-word level which means the vocabulary textbook-level is still far from students vocabulary knowledge. From the level of comparison theoretically they would have difficulties to comprehend the reading textbook, and some additional activities would be recommended, before, during and after the reading subject.

  13. Accuracy of student performance while reading leveled books rated at their instructional level by a reading inventory.

    Science.gov (United States)

    Burns, Matthew K; Pulles, Sandra M; Maki, Kathrin E; Kanive, Rebecca; Hodgson, Jennifer; Helman, Lori A; McComas, Jennifer J; Preast, June L

    2015-12-01

    Identifying a student's instructional level is necessary to ensure that students are appropriately challenged in reading. Informal reading inventories (IRIs) purport to assess the highest reading level at which a student can accurately decode and comprehend text. However, the use of IRIs in determining a student's instructional level has been questioned because of a lack of research. The current study examined the percentage of words read correctly with 64 second- and third-grade students while reading from texts at their instructional level as determined by an IRI. Students read for 1 min from three leveled texts that corresponded to their instructional level as measured by an IRI, and the percentage of words read correctly was recorded. The percentage read correctly correlated across the three books from r=.47 to r=.68 and instructional level categories correlated from tau=.59 to tau=.65. Percent agreement calculations showed that the categorical scores (frustration, instructional, and independent) for the three readings agreed approximately 67% to 70% of the time, which resulted in a kappa estimate of less than .50. Kappa coefficients of .70 are considered strong indicators of agreement. Moreover, more than half of the students with the lowest reading skills read at a frustration level when attempting to read books rated at their instructional level by an IRI. The current study questions how reliably and accurately IRIs identify students' instructional level for reading. Copyright © 2015 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

  14. The Effects of Extensive Reading via E-Books on Tertiary Level EFL Students' Reading Attitude, Reading Comprehension, and Vocabulary

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    Chen, Chin-Neng; Chen, Shu-Chu; Chen, Shu-Hui Eileen; Wey, Shyh-Chyi

    2013-01-01

    This study investigates the effects of extensive reading of e-books on tertiary level EFL students' English reading attitude, reading comprehension and vocabulary. Eighty-nine participants were assigned in two groups, with 46 students in the experimental group and the other 43 students in the control group. In addition to a traditional curriculum…

  15. Reading Ground Water Levels with a Smartphone

    Science.gov (United States)

    van Overloop, Peter-Jules

    2015-04-01

    Most ground water levels in the world are measured manually. It requires employees of water management organizations to visit sites in the field and execute a measurement procedure that requires special tools and training. Once the measurement is done, the value is jotted down in a notebook and later, at the office, entered in a computer system. This procedure is slow and prone to human errors. A new development is the introduction of modern Information and Communication Technology to support this task and make it more efficient. Two innovations are introduced to measure and immediately store ground water levels. The first method is a measuring tape that gives a sound and light when it just touches the water in combination with an app on a smartphone with which a picture needs to be taken from the measuring tape. Using dedicated pattern recognition algorithms, the depth is read on the tape and it is verified if the light is on. The second method estimates the depth using a sound from the smartphone that is sent into the borehole and records the reflecting waves in the pipe. Both methods use gps-localization of the smartphone to store the depths in the right location in the central database, making the monitoring of ground water levels a real-time process that eliminates human errors.

  16. Reading Strategies Employed by University Business English Majors with Different Levels of Reading Proficiency

    Science.gov (United States)

    Chen, Jun; Intaraprasert, Channarong

    2014-01-01

    The purpose of this study was to investigate the use of reading strategies by the university Business English majors in relation to their levels of reading proficiency. The participants were 926 university Business English majors from 6 universities in southwest China. The Strategy Questionnaire for Business English Reading (SQBER) and the…

  17. Beyond ORF: Student-Level Predictors of Reading Achievement

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    Canto, Angela I.; Proctor, Briley E.

    2013-01-01

    This study explored student-level predictors of reading achievement among third grade regular education students. Predictors included student demographics (sex and socioeconomic status (SES), using free and reduced lunch as proxy for SES), direct observations of reading skills (oral reading fluency (ORF) and word decoding skill (nonsense word…

  18. Oral reading fluency analysis in patients with Alzheimer disease and asymptomatic control subjects.

    Science.gov (United States)

    Martínez-Sánchez, F; Meilán, J J G; García-Sevilla, J; Carro, J; Arana, J M

    2013-01-01

    Many studies highlight that an impaired ability to communicate is one of the key clinical features of Alzheimer disease (AD). To study temporal organisation of speech in an oral reading task in patients with AD and in matched healthy controls using a semi-automatic method, and evaluate that method's ability to discriminate between the 2 groups. A test with an oral reading task was administered to 70 subjects, comprising 35 AD patients and 35 controls. Before speech samples were recorded, participants completed a battery of neuropsychological tests. There were no differences between groups with regard to age, sex, or educational level. All of the study variables showed impairment in the AD group. According to the results, AD patients' oral reading was marked by reduced speech and articulation rates, low effectiveness of phonation time, and increases in the number and proportion of pauses. Signal processing algorithms applied to reading fluency recordings were shown to be capable of differentiating between AD patients and controls with an accuracy of 80% (specificity 74.2%, sensitivity 77.1%) based on speech rate. Analysis of oral reading fluency may be useful as a tool for the objective study and quantification of speech deficits in AD. Copyright © 2012 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  19. Monocular and binocular reading performance in subjects with normal binocular vision.

    Science.gov (United States)

    Johansson, Jan; Pansell, Tony; Ygge, Jan; Seimyr, Gustaf Öqvist

    2014-07-01

    It is well known that problems with binocular vision can cause issues for reading; less known is to what extent binocular vision improves reading performance. The purpose of this study was to explore the role of binocularity by directly comparing monocular and binocular reading in subjects with typical reading skills and normal binocular vision. A secondary purpose was to assess any asymmetry in monocular performance and its association with the sighting dominant eye. In a balanced repeated measures experiment, 18 subjects read paragraphs of text under monocular and binocular conditions. All subjects went through an optometric examination before inclusion. Reading speed and eye movements were recorded with an eye tracker. The mean difference in reading speed (2.1 per cent) between monocular (dominant and non-dominant eye averaged) and binocular reading speed was not significant. A significant difference in reading speed was found between binocular and the non-dominant eye, as determined by the far sighting test (p = 0.03). Monocular reading showed significantly increased (8.9 per cent) fixation duration (p binocular vision, there is no marked enhancement in reading performance by binocular vision when reading paragraphs of text. Furthermore, the monocular reading performance appears to be close to equal and any small differences in performance appear not to be strongly associated with ocular dominance. © 2014 The Authors. Clinical and Experimental Optometry © 2014 Optometrists Association Australia.

  20. Relative Contributions of Caregivers' Level of Education, Role Definition and Average Household Income to Caregiver Involvement in Children's Emergent Reading

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    Wambiri, Gladwell N.; Ndani, Mary N.

    2015-01-01

    Recent studies have consistently reported low reading achievement levels among primary school children in Kenya. Reading is a very critical component of children's development. Many aspects of learning at school revolve around this skill. Being the media via which other subjects are taught and learnt, reading is very significant and could…

  1. Reading level of Overeaters Anonymous primary educational material.

    Science.gov (United States)

    Walfish, Steven; Pinholster, Katherine

    2008-01-01

    Educational materials are often a key component of recovery in a mutual-help group. However, in order to be helpful to a maximum number of members, these materials must be presented at a reading level that is comprehensible. Two measures of readability, The Flesch Reading Ease score and the Flesch-Kincaid Grade-Level score were applied to 20 random paragraphs chosen from The Twelve Steps and Twelve Traditions of Overeaters Anonymous. Results indicate that the average paragraph is written just below the tenth grade level and close to an optimum level of reading ease. However, due to variability, almost half (45%) of the paragraphs fell in the category of Difficult Reading Ease and half were found to be at a tenth grade reading level or beyond. In order to maximize the utility of this educational text, it is recommended that future editions take into consideration principles of readability.

  2. Comprehension after Oral and Silent Reading: Does Grade Level Matter?

    Science.gov (United States)

    Prior, Suzanne M.; Fenwick, Kimberley D.; Saunders, Katie S.; Ouellette, Rachel; O'Quinn, Chantell; Harvey, Shannon

    2011-01-01

    The study examines comprehension after oral and silent reading in elementary- and middle-school students. It investigates whether and when one mode is superior to the other for comprehension as children develop, independent of reading ability levels. One hundred and seventy three children in first through seventh grades orally and silently read…

  3. Reading in schizophrenic subjects and their nonsymptomatic first-degree relatives.

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    Roberts, Eryl O; Proudlock, Frank A; Martin, Kate; Reveley, Michael A; Al-Uzri, Mohammed; Gottlob, Irene

    2013-07-01

    Previous studies have demonstrated eye movement abnormalities during smooth pursuit and antisaccadic tasks in schizophrenia. However, eye movements have not been investigated during reading. The purpose of this study was to determine whether schizophrenic subjects and their nonsymptomatic first-degree relatives show eye movement abnormalities during reading. Reading rate, number of saccades per line, amplitudes of saccades, percentage regressions (reverse saccades), and fixation durations were measured using an eye tracker (EyeLink, SensoMotoric Instruments, Germany) in 38 schizophrenic volunteers, 14 nonaffected first-degree relatives, and 57 control volunteers matched for age and National Adult Reading Test scores. Parameters were examined when volunteers read full pages of text and text was limited to progressively smaller viewing areas around the point of fixation using a gaze-contingent window. Schizophrenic volunteers showed significantly slower reading rates (P = .004), increase in total number of saccades (P ≤ .001), and a decrease in saccadic amplitude (P = .025) while reading. Relatives showed a significant increase in total number of saccades (P = .013) and decrease in saccadic amplitude (P = .020). Limitation of parafoveal information by reducing the amount of visible characters did not change the reading rate of schizophrenics but controls showed a significant decrease in reading rate with reduced parafoveal information (P reading of schizophrenic volunteers and their first-degree relatives suggest that visual integration of foveal and parafoveal information may be reduced in schizophrenia. Reading abnormalities in relatives suggest a genetic influence in reading ability in schizophrenia and rule out confounding effects of medication.

  4. The Impact of Vocabulary Knowledge Level on EFL Reading Comprehension

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    Shima Kameli

    2013-01-01

    Full Text Available The present study examined the impact of vocabulary knowledge level on reading comprehension performance among EFL language learners. The ultimate intention was to determine the association between levels of vocabulary knowledge and to clarify the relationship among vocabulary knowledge on reading comprehension performance of EFL Iranian students on subtest of VLT and IELTS. Quantitative data were collected from 220 EFL Iranian adult students at the beginning of second semester of 2011 in private English language institute (BAHAR, Shiraz, Iran. The Vocabulary Levels Test (VLT and Reading Comprehension Test (IELTS were performed in one session as research instruments. The findings indicated that there were positive relationships among different levels of vocabulary test and also test scores on vocabulary size/breadth of vocabulary knowledge, and reading comprehension.

  5. Analysis of Reading Comprehension Levels of Fifth Grade Students Who Learned to Read and Write with the Sentence Method

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    Sagirli, Muhittin

    2016-01-01

    The purpose of this study is the determination of reading comprehension levels of fifth grade's students who learned to read and write with the sentence method. With the program of 2005, it has been amended in the first reading and writing method. In the teaching of first reading and writing, it was passed to the sentence method instead of sound…

  6. Reading Intervention: The Effectiveness of Leveled Literacy Intervention

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    Burton-Archie, Sonya H.

    2014-01-01

    Reading challenges are still evident for more than 90 million adults in the United States who are functioning at the lowest levels of literacy (United States Department of Education, 2004). Leveled Literacy Intervention (LLI) is one program designed to address these educational needs. The purpose of this quantitative study was to investigate the…

  7. Analyzing the Reading Skills and Visual Perception Levels of First Grade Students

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    Çayir, Aybala

    2017-01-01

    The purpose of this study was to analyze primary school first grade students' reading levels and correlate their visual perception skills. For this purpose, students' reading speed, reading comprehension and reading errors were determined using The Informal Reading Inventory. Students' visual perception levels were also analyzed using…

  8. Listening and Reading Proficiency Levels of College Students

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    Tschirner, Erwin

    2016-01-01

    This article examines listening and reading proficiency levels of U.S. college foreign language students at major milestones throughout their undergraduate career. Data were collected from more than 3,000 participants studying seven languages at 21 universities and colleges across the United States. The results show that while listening…

  9. University Level Second Language Readers' Online Reading and Comprehension Strategies

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    Park, Jaehan; Yang, Jaeseok; Hsieh, Yi Chin

    2014-01-01

    With the growing prevalence of Web 2.0 technologies and use of online resources in their classrooms, language learners have increasing exposure to online texts. In this study we attempted to understand how university level second language (L2) readers construct meaning when reading online. We investigated L2 readers' information-seeking strategies…

  10. Braille Reading Is Less Efficient Than Visual Reading.

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    Williamson, Leon E.; And Others

    The reading performances of fifteen blind readers and fifteen sighted readers were compared by evaluating the reading performances of each reader reading at instructional level from Lippincott's "Basic Reading Series" and from Form A of the "Gray Oral Reading Test." Nine matched pairs of subjects read at grade one first reader level and six pairs…

  11. Soluble serum Klotho levels in healthy subjects

    DEFF Research Database (Denmark)

    Pedersen, Lise Mariager; Pedersen, Susanne Møller; Brasen, Claus Lohman

    2013-01-01

    Klotho concentrations were determined in 120 healthy adults aged 19-66years. Blood samples were collected, and stored sera were assayed for Klotho according to age and gender. In addition several other clinical and laboratory characteristics were determined in the cohort and compared to the levels......OBJECTIVE: Soluble serum Klotho, is a new biomarker linked to chronic kidney disease, cardiovascular disease and diabetes. This study describes the evaluation and comparison of two different immunoassays and establishment of assay specific reference intervals in adults. Design and methods Serum...... of serum Klotho. RESULTS: Serum Klotho levels were significantly higher in time-resolved fluorescence immunoassay (TRF) compared to an ELISA (IBL) and no correlation were found between the assays. No signal was obtained in either assay when the standard curve was switched between the two different...

  12. Pathway evidence of how musical perception predicts word-level reading ability in children with reading difficulties.

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    Cogo-Moreira, Hugo; Brandão de Ávila, Clara Regina; Ploubidis, George B; de Jesus Mari, Jair

    2013-01-01

    To investigate whether specific domains of musical perception (temporal and melodic domains) predict the word-level reading skills of eight- to ten-year-old children (n = 235) with reading difficulties, normal quotient of intelligence, and no previous exposure to music education classes. A general-specific solution of the Montreal Battery of Evaluation of Amusia (MBEA), which underlies a musical perception construct and is constituted by three latent factors (the general, temporal, and the melodic domain), was regressed on word-level reading skills (rate of correct isolated words/non-words read per minute). General and melodic latent domains predicted word-level reading skills.

  13. The Influence of Psychophysiological Variables on Aged Subjects' Functional Reading Achievement.

    Science.gov (United States)

    Lovelace, Terry

    A study investigated the effects of selected psychophysiological factors known to affect cognitive functioning on the reading achievement of older adults. The subjects, 34 noninstitutionalized adults ranging in age from 50 to 88 years, completed measures of (1) self-reported mental and physical health, (2) nonverbal intelligence, (3) reading…

  14. The Role of Reading Comprehension in Large-Scale Subject-Matter Assessments

    Science.gov (United States)

    Zhang, Ting

    2013-01-01

    This study was designed with the overall goal of understanding how difficulties in reading comprehension are associated with early adolescents' performance in large-scale assessments in subject domains including science and civic-related social studies. The current study extended previous research by taking a cognition-centered approach based on…

  15. The Relationship of Reading Comprehension Success with Metacognitive Awareness, Motivation, and Reading Levels of Fifth Grade Students

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    Memis, Aysel; Bozkurt, Metin

    2013-01-01

    This research aims to investigate the relationship between metacognitive awareness, reading motivations, reading levels and reading comprehension success of fifth grade students using comparative relative scan model. There were 577 students. In the result of the research, in which data were collected with four scales, it was concluded that reading…

  16. Using the TOEFL to measure the reading proficiency levels of deaf college applicants.

    Science.gov (United States)

    LoMaglio, L J

    1991-07-01

    The TOEFL is widely used by colleges and universities in the United States and Canada to measure the English language proficiency levels of hearing international applicants. At the National Technical Institute for the Deaf, a faculty committee recommended that this popular test instrument be used to measure the English reading skills of deaf international applicants to the National Technical Institute for the Deaf. This study examined the merits of using the TOEFL to measure the English reading ability of hearing post-secondary international students seeking admission to English-based colleges and universities. Forty-one hearing foreign students were tested in the fall of 1989 at the English Language Institute at SUNY Buffalo. The instruments chosen were both the TOEFL and the California Achievement Test of reading ability. The majority of the research subjects who scored between 400 and 500 on the TOEFL achieved a grade level of less than 8.0 on the California Achievement Test.

  17. Congenital vs acquired deafness: differences in reading and mathematics levels.

    Science.gov (United States)

    DeLeon, B; Berg, R A; Battin, R R

    1979-04-01

    Measures of reading ability and math skills were taken in 22 adults who were either congenitally deaf or had acquired deafness in the second or third year of life. Both groups were equivalent with respect to I.Q., education level and degree of loss. The following tests were administered: (1) the performance scale of the Weschler Adult Intelligence Scale, (2) the math section of the Wide Range Achievement Test, (3) the Reading Comprehension subtest of the Peabody Individual Achievement Test, and (4) the Raven Test of Progressive Matrices. There were no significant differences between the two groups on reading level, but a significantly higher math level was found in the congenital group. It was suggested that the pathology in the acquired group may have affected other neural centers in addition to the auditory, or that the acquired group may have been handicapped by the possibility of switching from one coding system (auditory) to another (visual), while in the congenital group the coding remained confined to the visual mode.

  18. The interpupillary distance in adult Caucasian subjects, with reference to 'readymade' reading spectacle centration.

    Science.gov (United States)

    Pointer, Jonathan S

    2012-07-01

    The magnitude of the far interpupillary distance (FIPD) has recognized significance within and beyond clinical optometry. Quantitative information regarding the lesser-reported near parameter (NIPD) would similarly be of interest, and could be of relevance with regard to the visual comfort obtained with 'readymade' reading spectacles. Mensuration statistics relating to the FIPD and NIPD are presented, as collated from the spectacle dispensing records of n = 1354 healthy Caucasian presbyopic subjects. The FIPD data were partitioned across 4 age bands (by decade, 41-80 years of age): the NIPD data were distributed across seven nominal reading powers (in 0.50 D steps, +1.00 to +4.00 D). The results of these analyses are considered here, along with their potential application. Consistent gender (male > female) and classification (far > near) differences in IPD (both of approximately 3 mm) were confirmed throughout these data. The magnitude of the adult FIPD is in accord with previously published results; this dimension is now supplemented by NIPD values, whose relationship with total near power is also described. This new anthropometric survey indicates that inter- and intra-gender interocular facial measurement stability is a characteristic of presbyopic subjects. It is suggested that across the anticipated range of age and total reading power requirement of Caucasian (White Northern European) wearers of 'readymade' reading spectacles, adoption of a standard optical centration distance of 61 mm would be universally appropriate. Ophthalmic & Physiological Optics © 2012 The College of Optometrists.

  19. Effects of Different Text Difficulty Levels on EFL Learners' Foreign Language Reading Anxiety and Reading Comprehension

    Science.gov (United States)

    Bahmani, Roghayeh; Farvardin, Mohammad Taghi

    2017-01-01

    This study aimed to examine the effects of different text difficulty levels on foreign language reading anxiety (FLRA) and reading comprehension of English as a Foreign Language (EFL) learners. To this end, 50 elementary EFL learners were selected from two intact classes (n = 25 each). Each class was assigned to a text difficulty level (i.e.,…

  20. Do changes in socialization lead to decline in reading level? How parents, literary education, and popular culture affect the level of books read

    NARCIS (Netherlands)

    Verboord, Marc; Rees, Kees van

    2003-01-01

    The influence of reading socialization on the level of books read in adult life was investigated for birth cohorts who finished secondary education between 1975 and 1998. Three forms of reading socialization were taken into account: socialization in the parental home, literary socialization at

  1. Item response theory at subject- and group-level

    NARCIS (Netherlands)

    Tobi, Hilde

    1990-01-01

    This paper reviews the literature about item response models for the subject level and aggregated level (group level). Group-level item response models (IRMs) are used in the United States in large-scale assessment programs such as the National Assessment of Educational Progress and the California

  2. Inter-subject variability in the use of two different neuronal networks for reading aloud familiar words.

    Science.gov (United States)

    Seghier, M L; Lee, H L; Schofield, T; Ellis, C L; Price, C J

    2008-09-01

    Cognitive models of reading predict that high frequency regular words can be read in more than one way. We investigated this hypothesis using functional MRI and covariance analysis in 43 healthy skilled readers. Our results dissociated two sets of regions that were differentially engaged across subjects who were reading the same familiar words. Some subjects showed more activation in left inferior frontal and anterior occipito-temporal regions while other subjects showed more activation in right inferior parietal and left posterior occipito-temporal regions. To explore the behavioural correlates of these systems, we measured the difference between reading speed for irregularly spelled words relative to pseudowords outside the scanner in fifteen of our subjects and correlated this measure with fMRI activation for reading familiar words. The faster the lexical reading the greater the activation in left posterior occipito-temporal and right inferior parietal regions. Conversely, the slower the lexical reading the greater the activation in left anterior occipito-temporal and left ventral inferior frontal regions. Thus, the double dissociation in irregular and pseudoword reading behaviour predicted the double dissociation in neuronal activation for reading familiar words. We discuss the implications of these results which may be important for understanding how reading is learnt in childhood or re-learnt following brain damage in adulthood.

  3. Adapting Self-Selected Reading Practices for College-Level Developmental Reading Courses

    Science.gov (United States)

    Flink, Patrick J.

    2017-01-01

    Reading comprehension and fluency issues are the most significant challenges facing adult, developmental reading students in community colleges. While a great deal of focus has been on improving developmental reading instruction, there is a lack of attention, and research, on how to best improve students' actual reading. Self-selected reading…

  4. Promoting Different Reading Comprehension Levels through Online Annotations

    Science.gov (United States)

    Tseng, Sheng-Shiang; Yeh, Hui-Chin; Yang, Shih-hsien

    2015-01-01

    Previous studies have evaluated reading comprehension as the general understanding of reading texts. However, this broad and generic assessment of reading comprehension overlooks the specific aspects and processes that students need to develop. This study adopted Kintsch's Construction-Integration model to tap into reading comprehension at…

  5. Serum alphafetoprotein levels in subjects infected with hepatitis B virus.

    Science.gov (United States)

    Kitau, M J; Grint, P C; Heath, R B; Chard, T

    1988-12-01

    Serum alphafetoprotein (AFP) levels were measured using a sensitive radioimmunoassay in 108 hepatitis B surface antigen (HBsAg)-positive subjects and 695 controls. The concentrations were significantly higher in the HBsAg-positives. Within this group, the highest levels were found in those with active HBV infection. In those without evidence of acute infection, the levels were higher in the high-risk than in the low-risk subjects. It is concluded: 1) that measurement of serum AFP might be a useful additional index of infectivity and prognosis in HBsAg-positive subjects; and 2) that in the light of the association between chronic HBV infection, hepatocellular carcinoma, and raised AFP in non-European populations, consideration should be given to regular monitoring of AFP levels in HBsAg-positive subjects in the United Kingdom.

  6. Relative effectiveness of reading practice or word-level instruction in supplemental tutoring: how text matters.

    Science.gov (United States)

    Vadasy, Patricia F; Sanders, Elizabeth A; Peyton, Julia A

    2005-01-01

    In this quasi-experimental study, which is part of a series of investigations on supplemental reading tutoring variations, the relative effectiveness of more intense decoding instruction or text reading practice was examined. Fifty-seven first-grade students scoring in the lowest quartile for reading skills received either classroom reading instruction or one of two treatments: tutoring in word study with text reading practice, or word study tutoring alone. Individual instruction was provided by trained paraprofessional tutors. At the end of first grade, treatment students significantly outperformed their nontutored peers on measures of reading accuracy, reading comprehension, reading efficiency, passage reading fluency, and spelling. Differential treatment effects on passage reading fluency are examined, taking into consideration pretest skill levels and text reading practice characteristics.

  7. Pathway evidence of how musical perception predicts word-level reading ability in children with reading difficulties.

    Directory of Open Access Journals (Sweden)

    Hugo Cogo-Moreira

    Full Text Available OBJECTIVE: To investigate whether specific domains of musical perception (temporal and melodic domains predict the word-level reading skills of eight- to ten-year-old children (n = 235 with reading difficulties, normal quotient of intelligence, and no previous exposure to music education classes. METHOD: A general-specific solution of the Montreal Battery of Evaluation of Amusia (MBEA, which underlies a musical perception construct and is constituted by three latent factors (the general, temporal, and the melodic domain, was regressed on word-level reading skills (rate of correct isolated words/non-words read per minute. RESULTS: General and melodic latent domains predicted word-level reading skills.

  8. The Effects of Reading from the Screen on the Reading Motivation Levels of Elementary 5th Graders

    Science.gov (United States)

    Aydemir, Zeynep; Ozturk, Ergun

    2012-01-01

    This study aims to explore the effects of reading from the screen on elementary 5th grade students' reading motivation levels. It used the randomized control-group pretest-posttest model, which is a true experimental design. The study group consisted of 60 students, 30 experimental and 30 control, who were attending the 5th grade of a public…

  9. Boosting Reading Fluency: An Intervention Case Study at Subword Level

    Science.gov (United States)

    Kairaluoma, Leila; Ahonen, Timo; Aro, Mikko; Holopainen, Leena

    2007-01-01

    This study is an intervention case study of fluency in Finnish-speaking children with dyslexia. Two 7-year-old children, a girl and a boy, were selected from the Jyvaskyla Longitudinal Study of Dyslexia. The intervention emphasised syllables as reading units, and proceeded from reading syllables to reading words and text. Letter knowledge, reading…

  10. Waterford Early Reading Level One[TM]. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2007

    2007-01-01

    "Waterford Early Reading Level One"[TM] is an emergent literacy curriculum that uses computer-based technology to prepare children for reading. It begins with a tutorial to familiarize the child with the computer and mouse and a reading placement evaluation to assess and determine whether a child should work on "Level One"…

  11. DISGNOSIS BABEL AND SCHOOL INCLUSION OF SUBJECTS WITH AUTISM AND CHILD PSYCHOSIS: ACTS OF A READING

    Directory of Open Access Journals (Sweden)

    Carla Vasques

    2009-06-01

    Full Text Available This text addresses the schooling of children and adolescents with serious developmental impairment or with atypical structuring, such as autism or psychosis. That field is vast and complex, the perspective adopted builds on Freud-lacanian psychoanalysis, philosophical-hermeneutics, special education and inclusive processes. Specifically, a reflection is posed on the place the diagnosis has in the construction of (impossibilities within school based on the analysis of academic and scientific production on the issue for the past 28 years. The proposition is that diagnosis in central in the establishment of educational pathways for such subjects. Diagnosis is often identified as an act of unveiling and/or decoding. From another perspective, it is defended that the relationship diagnosis-schooling implies the construction of a reading, the invention of possibilities. As it is not possible to determine the veracity of diverse theories, a schooling process includes constitutive unknowing. As there is no path pre-established guaranteed and anticipated bythe diagnosis, teachers and school are responsible for their choices aiming their students school experience. Thus, the basis of their action is ethics, not a method or technique. As a metaphor of the interpretative work. I present the image of a library that is constructed, offers, inscribes and subscribes to the meeting between text and reader. Placing the library as a privileged space of such argumentation implies in taking language and reading as the center of discussions. It is a displacement of the focus of attention of the subject with autism or psychosis to the teacher, the other, who reads, interprets and builds schooling (inpossibilities. Key words: Autism; Child psychosis; Diagnosis; School inclusion.

  12. Subjective impressions do not mirror online reading effort: concurrent EEG-eyetracking evidence from the reading of books and digital media.

    Directory of Open Access Journals (Sweden)

    Franziska Kretzschmar

    Full Text Available In the rapidly changing circumstances of our increasingly digital world, reading is also becoming an increasingly digital experience: electronic books (e-books are now outselling print books in the United States and the United Kingdom. Nevertheless, many readers still view e-books as less readable than print books. The present study thus used combined EEG and eyetracking measures in order to test whether reading from digital media requires higher cognitive effort than reading conventional books. Young and elderly adults read short texts on three different reading devices: a paper page, an e-reader and a tablet computer and answered comprehension questions about them while their eye movements and EEG were recorded. The results of a debriefing questionnaire replicated previous findings in that participants overwhelmingly chose the paper page over the two electronic devices as their preferred reading medium. Online measures, by contrast, showed shorter mean fixation durations and lower EEG theta band voltage density--known to covary with memory encoding and retrieval--for the older adults when reading from a tablet computer in comparison to the other two devices. Young adults showed comparable fixation durations and theta activity for all three devices. Comprehension accuracy did not differ across the three media for either group. We argue that these results can be explained in terms of the better text discriminability (higher contrast produced by the backlit display of the tablet computer. Contrast sensitivity decreases with age and degraded contrast conditions lead to longer reading times, thus supporting the conclusion that older readers may benefit particularly from the enhanced contrast of the tablet. Our findings thus indicate that people's subjective evaluation of digital reading media must be dissociated from the cognitive and neural effort expended in online information processing while reading from such devices.

  13. Subjective impressions do not mirror online reading effort: concurrent EEG-eyetracking evidence from the reading of books and digital media.

    Science.gov (United States)

    Kretzschmar, Franziska; Pleimling, Dominique; Hosemann, Jana; Füssel, Stephan; Bornkessel-Schlesewsky, Ina; Schlesewsky, Matthias

    2013-01-01

    In the rapidly changing circumstances of our increasingly digital world, reading is also becoming an increasingly digital experience: electronic books (e-books) are now outselling print books in the United States and the United Kingdom. Nevertheless, many readers still view e-books as less readable than print books. The present study thus used combined EEG and eyetracking measures in order to test whether reading from digital media requires higher cognitive effort than reading conventional books. Young and elderly adults read short texts on three different reading devices: a paper page, an e-reader and a tablet computer and answered comprehension questions about them while their eye movements and EEG were recorded. The results of a debriefing questionnaire replicated previous findings in that participants overwhelmingly chose the paper page over the two electronic devices as their preferred reading medium. Online measures, by contrast, showed shorter mean fixation durations and lower EEG theta band voltage density--known to covary with memory encoding and retrieval--for the older adults when reading from a tablet computer in comparison to the other two devices. Young adults showed comparable fixation durations and theta activity for all three devices. Comprehension accuracy did not differ across the three media for either group. We argue that these results can be explained in terms of the better text discriminability (higher contrast) produced by the backlit display of the tablet computer. Contrast sensitivity decreases with age and degraded contrast conditions lead to longer reading times, thus supporting the conclusion that older readers may benefit particularly from the enhanced contrast of the tablet. Our findings thus indicate that people's subjective evaluation of digital reading media must be dissociated from the cognitive and neural effort expended in online information processing while reading from such devices.

  14. Meeting the Needs of Struggling Readers: Using Reading Assessments in a Graduate-Level Reading Course

    Science.gov (United States)

    Oslick, Mary Ellen; Lane, Hannah

    2014-01-01

    The purpose of this research is to share the reading assessments that graduate students selected for their clinical practice with struggling readers. After a careful look at assessments, their place in the recent shift to Response to Intervention (RTI), specifically regarding reading instruction and the preparation of reading…

  15. Investigating the Relationship between Connectives and Readers' Reading Comprehension Level

    Science.gov (United States)

    Gençer, Yusuf; ÇetiInkaya, Gökhan

    2015-01-01

    The purpose of this study is to investigate the relationship between connectives in Turkish texts and readers' reading comprehension. Research was conducted with a total of 50 teachers. In the study group, readers' reading comprehension was determined through 10 descriptive texts by using open-ended questions. The results of the analysis revealed…

  16. The Impact of Metacognition Strategies on Reading Comprehension Levels of Nonproficient High School Students

    Science.gov (United States)

    Manderville, Tonya Butler

    2012-01-01

    At one high school, the goal for nonproficient reading students was to score at or above the 50th percentile to meet adequate yearly progress objectives. In 2010, the performance levels of nonproficient reading students tested with the state reading test in Grades 9 and 10 declined from the 47th to the 46th percentile. The purpose of this research…

  17. Metabolic rate and cardiorespiratory response during hybrid cycling versus handcycling at equal subjective exercise intensity levels in people with spinal cord injury

    NARCIS (Netherlands)

    Bakkum, Arjan J. T.; de Groot, Sonja; Onderwater, Mark Q.; de Jong, Jelle; Janssen, Thomas W. J.

    2014-01-01

    Objective: To compare the metabolic rate and cardiorespiratory response during hybrid cycling versus handcycling at equal subjective exercise intensity levels in people with spinal cord injury (SCI). Design: Cross-sectional study. Setting: Amsterdam Rehabilitation Research Centre vertical bar Reade,

  18. Different alternative splicing patterns are subject to opposite selection pressure for protein reading frame preservation

    Directory of Open Access Journals (Sweden)

    Chuang Trees-Juen

    2007-09-01

    Full Text Available Abstract Background Alternative splicing (AS has been regarded capable of altering selection pressure on protein subsequences. Particularly, the frequency of reading frame preservation (FRFP, as a measure of selection pressure, has been reported to be higher in alternatively spliced exons (ASEs than in constitutively spliced exons (CSEs. However, recently it has been reported that different ASE types – simple and complex ASEs – may be subject to opposite selection forces. Therefore, it is necessary to re-evaluate the evolutionary effects of such splicing patterns on frame preservation. Results Here we show that simple and complex ASEs, respectively, have higher and lower FRFPs than CSEs. Since complex ASEs may alter the ends of their flanking exons, the selection pressure on frame preservation is likely relaxed in this ASE type. Furthermore, conservation of the ASE/CSE splicing pattern increases the FRFPs of simple ASEs but decreases those of complex ASEs. Contrary to the well-recognized concept of strong selection pressure on conserved ASEs for protein reading frame preservation, our results show that conserved complex ASEs are relaxed from such pressure and the frame-disrupting effect caused by the insertion of complex ASEs can be offset by compensatory changes in their flanking exons. Conclusion In this study, we find that simple and complex ASEs undergo opposite selection pressure for protein reading frame preservation, with CSEs in-between. Simple ASEs have much higher FRFPs than complex ones. We further find that the FRFPs of complex ASEs coupled with flanking exons are close to those of simple ASEs, indicating that neighboring exons of an ASE may evolve in a coordinated way to avoid protein dysfunction. Therefore, we suggest that evolutionary analyses of AS should take into consideration the effects of different splicing patterns and the joint effects of multiple AS events.

  19. SYNTACTIC COMPLEXITY IN THE READING MATERIALS OF ENGLISH FOR ACADEMIC PURPOSES LEVELS 1 – 3

    Directory of Open Access Journals (Sweden)

    Widdy Wijanti

    2017-10-01

    Full Text Available LLT Journal: A Journal on Language and Language Teaching Open Journal Systems LLT Journal ISSNs: e-ISSN: 2579-9533 (electronic p-ISSN: 1410-7201 (print User Username Password Remember me Journal Content Search Search Scope Browse By Issue By Author By Title Other Journals Font Size Make font size smaller Make font size default Make font size larger LLT Journal Barcode TOOLS FULL PAPER GUIDELINES Article Tools Print this article Indexing metadata How to cite item Email this article (Login required Email the author (Login required About The Author Widdy Wijanti Sampoerna University, Jakarta Indonesia OUR CONTACT LLT Journal English Language Education Sanata Dharma University Yogyakarta, Indonesia For more details, please visit: LLT Journal Contact Address Home About Login Register Search Current Archives Author Guidelines Editorial Team Focus and Scope Publication Ethics Author Index Originality Screening Indexing and Abstracting Review Process Article Processing Charges Article Submission Charges Publishing Rights Peer Reviewers Home > Vol 20, No 2 (2017 > Wijanti SYNTACTIC COMPLEXITY IN THE READING MATERIALS OF ENGLISH FOR ACADEMIC PURPOSES LEVELS 1 – 3 Widdy Wijanti Abstract In Indonesia, English is still considered as a foreign language and has become a crucial subject of study especially in the university level. For this reason, English for Academic Purposes has been conducted in the first year of college level for many years. Unfortunately, although many Asian countries including Indonesia have run the EAP course, the output is that there are still many Indonesian students who do not meet the vocabulary size and syntactic complexity that are expected while their learning process in the university. This results lower grades that they have in their assignments. Therefore, the recent study is aimed at evaluating the reading materials of EAP, especially in measuring the syntactic complexity containing in the texts as it is strongly believed in

  20. Reading virtual slide using web viewers: results of subjective experience with three different solutions.

    Science.gov (United States)

    Rojo, Marcial García; Gallardo, Antonio J; González, Lucía; Peces, Carlos; Murillo, Cristina; González, Jesús; Sacristán, Jose

    2008-07-15

    Virtual slides are viewed using interactive software that enables the user to simulate the behaviour of a conventional optical microscope, like adjusting magnifications and navigating to any portion of the image. Nowadays, information about the performance and features of web-based solutions for reading slides in real environments is still scarce. The objective of this study is analyzing the subjective experience of pathologists with virtual slides, comparing the time needed to read slides using different web viewers and different network connections. Eight slides were randomly selected (4 biopsies and 2 cytologies) from Hospital General de Ciudad Real (HGCR) archives. Three different virtual slide web-viewing solutions were analyzed: Aperio web server, Olympus NetImage Server, and Aurora mScope. Five pathologists studied to time needed to access images of each virtual slide, selecting a panoramic view, 10 low magnification fields, and 20 high magnification fields. Aperio viewer is very efficient in overview images. Aurora viewer is especially efficient in lower magnifications (10x). For larger magnifications (20x and 40x) no significant differences were found between different vendors. Olympus was found to be the most user-friendly interface. When comparing Internet with intranet connections, despite being slower, users also felt comfortable using virtual slides through Internet connection. Available web solutions for virtual slides have different advantages, mainly in functionalities and optimization for different magnifications. Pathologists should select the solutions adapted to their needs.

  1. Sleep enhances nocturnal plasma ghrelin levels in healthy subjects.

    Science.gov (United States)

    Dzaja, Andrea; Dalal, Mira A; Himmerich, Hubertus; Uhr, Manfred; Pollmächer, Thomas; Schuld, Andreas

    2004-06-01

    Ghrelin, an endogenous ligand of the growth hormone secretagogue receptor, has been shown to promote slow-wave sleep (SWS, non-REM sleep stages 3 and 4). Plasma levels of ghrelin are dependent on food intake and increase in sleeping subjects during the early part of the night. It is unknown whether sleep itself affects ghrelin levels or whether circadian networks are involved. Therefore, we studied the effect of sleep deprivation on nocturnal ghrelin secretion. In healthy male volunteers, plasma levels of ghrelin, cortisol, and human growth hormone (hGH) were measured during two experimental sessions of 24 h each: once when the subjects were allowed to sleep between 2300 and 0700 and once when they were kept awake throughout the night. During sleep, ghrelin levels increased during the early part of the night and decreased in the morning. This nocturnal increase was blunted during sleep deprivation, and ghrelin levels increased only slightly until the early morning. Ghrelin secretion during the first hours of sleep correlated positively with peak hGH concentrations. We conclude that the nocturnal increase in ghrelin levels is more likely to be caused by sleep-associated processes than by circadian influences. During the first hours of sleep, ghrelin might promote sleep-associated hGH secretion and contribute to the promotion of SWS.

  2. Online Test Tool to Determine the CEFR Reading Comprehension Level of Text

    NARCIS (Netherlands)

    Velleman, Eric Martin; van der Geest, Thea

    2014-01-01

    On the Common European Framework of Reference for Languages (CEFR) scale, the average reading comprehension level of the Dutch population is B1 and the average level of text provided by Dutch government organisations requires a considerably higher reading skills level (C1). This means that part of

  3. Discourse level reading comprehension interventions following acquired brain injury: a systematic review.

    Science.gov (United States)

    Watter, Kerrin; Copley, Anna; Finch, Emma

    2017-02-01

    Purpose Reading comprehension can change following acquired brain injury (ABI), impacting independence and participation. This review aims to identify and evaluate the interventions used for rehabilitation of discourse level reading in adults with ABI. Methods A systematic review was conducted of published journal articles. Methodological quality of studies was reviewed using formal and informal rating scales. Inclusion criteria involved adults with non-progressive ABI who experienced discourse level reading deficits related to aphasia or cognitive-communication disorders. Results A total of 23 studies were identified; these included randomized controlled trials, cohort and case studies. Six different types of reading interventions were found, overall results of these interventions were mixed. Reading deficits were reportedly related to language (aphasia) and/or cognitive deficits, with assessment processes varying. Questions arose regarding comparability of assessment methods and diagnostic issues across the studies. Conclusions Interventions for discourse level reading comprehension can make positive changes to reading function. However, no intervention was identified as a gold standard. A trend toward strategy-based reading was found, with these offering a potential for (comparatively) cost-effective lower-dosage reading treatments with positive-trend results. Cognitive and language features should be considered for assessment and intervention planning for discourse reading in ABI. Implications for Rehabilitation Six different types of discourse reading comprehension interventions for people with ABI were identified, with mixed evidence for each intervention. Clinicians need to consider both the linguistic and cognitive features of reading for assessment and intervention planning for discourse level reading. There is a research trend toward strategy-based reading interventions, which use a lower treatment dosage.

  4. Subject oriented and problem based text materials as a subject of flexible foreign language reading in research projects

    OpenAIRE

    SEROVA TAMARA S.; PIPCHENKO ELENA L.

    2014-01-01

    The article introduces the academic research work of students within the competence based approach, the models of academic problem based research projects taken up as a means to develop flexible foreign language reading skills. The authors reveal selection principles and corpus didactic design of text materials in the form of a macrotext, hypertext, and video course.

  5. The Analysis of Reading Skills and Visual Perception Levels of First Grade Turkish Students

    Science.gov (United States)

    Memis, Aysel; Sivri, Diler Ayvaz

    2016-01-01

    In this study, primary school first grade students' reading skills and visual perception levels were investigated. Sample of the study, which was designed with relational scanning model, consisted of 168 first grade students studying at three public primary schools in Kozlu, Zonguldak, in 2013-2014 education year. Students' reading level, reading…

  6. The Effects of Control for Ability Level on EFL Reading of Graded Readers

    Science.gov (United States)

    Wan-a-rom, Udorn

    2012-01-01

    The study was aimed to examine how EFL learners of English reacted to graded readers in terms of reading strategy use, comprehension, speed, and attitude as well as motivation when control for ability level was determined. Eighty Thai high school students placed into their own reading level of graded readers by the scores gained from the graded…

  7. Designing EAP Reading Courses at the University Level.

    Science.gov (United States)

    Spector-Cohen, E.; Kirschner, M.; Wexler, C.

    2001-01-01

    Presents the complementary Pyramid Syllabus Design (CPSD), developed at the Division of Foreign Languages, Tel Aviv University, Israel. The CPSD is a principled four-pronged approach to an English for Academic purposes reading course design employing elements of a Type A syllabus, one that focuses on the discrete elements of language. (Author/VWL)

  8. Libro de Lectura. Nivel A. (Reading Book. Level A.).

    Science.gov (United States)

    Yeats, Alid; And Others

    This is the first in a series of four reading books written in Spanish and designed for use in elementary bilingual education programs. The stories are divided into two main sections, Estudios Sociales (Social Studies) and La Naturaleza (Nature). The five stories in the first section deal with such topics as the home, school, and cleaning. The…

  9. Libro de Lectura. Nivel C. (Reading Book. Level C.).

    Science.gov (United States)

    Yeats, Alid

    This is the third in a series of four reading books written in Spanish and designed for use in elementary bilingual education programs. The reader contains nine stories, most of which deal with some aspect of nature study, such as plants or insects. Each story is followed by a list of new vocabulary and enrichment exercises and activities in the…

  10. Libro de Lectura. Nivel B. (Reading Book. Level B.).

    Science.gov (United States)

    Yeats, Alid; And Others

    This is the second in a series of four reading books written in Spanish and designed for use in elementary bilingual education programs. The stories are divided into two main sections, Estudios Sociales (Social Studies), and La Comunidad (The Community). The stories in the first section have to do with activities in the home, particularly chores…

  11. Cytokine and chemokine levels in tears from healthy subjects.

    Science.gov (United States)

    Carreño, Ester; Enríquez-de-Salamanca, Amalia; Tesón, Marisa; García-Vázquez, Carmen; Stern, Michael E; Whitcup, Scott M; Calonge, Margarita

    2010-11-01

    There is growing evidence for the existence of an 'immune tone' in normal tears. The aim of this study was to determine the levels of a large panel of cytokines and chemokines in tears obtained from healthy subjects. These levels can then serve as baseline values for comparison with patients suffering from ocular surface diseases. Nine healthy subjects participated in this study, and normal ocular surface health was documented by the results of a dry eye questionnaire, Schirmer strip wetting, and vital staining of the cornea. Four microliters of tears were collected from each eye and analysed separately with multiplex bead-based assays for the concentration of 30 cytokines and chemokines. Twenty-five cytokines/chemokines were detected. CCL11/Eotaxin1, GM-CSF, G-CSF, IFN-γ, IL-2, IL-3, IL-4, IL-5, IL-10, IL-13, IL-12p70, IL-15, CX3CL1/Fractalkine, TNF-α, epidermal growth factor, and CCL4/MIP-1β were present at 5-100 pg/ml. IL-1β, IL-6, IL-7A, CXCL8/IL-8, and CCL2/MCP-1 were present at 100-400 pg/ml. IL-1Ra, CXCL10/IP-10 and vascular endothelial growth factor were present at more than 1000 pg/ml. Multiplex bead-based assays are convenient for cytokine/chemokine detection in tears. Fracktalkine has been detected in human healthy tears for the first time. The knowledge of cytokine/chemokine concentrations in tears from normal subjects is an important reference for further comparison with patients suffering from ocular surface diseases. Variability in their levels can reflect a phenomenon of potential importance for the understanding of the ocular surface cytokine pattern. © 2010 The Authors. Journal compilation © 2010 Acta Ophthalmol.

  12. Factors Affecting Result in Chinese Proficiency Test (HSK Level 6: Reading Section and Preparation Strategies

    Directory of Open Access Journals (Sweden)

    Sri Haryanti

    2013-11-01

    Full Text Available Chinese Proficiency Test (HSK is an internationally standardized exam which tests and rates Chinese language proficiency. The highest level in this test is level 6. The writing part of the test consists of 3 (three parts, namely, (1 listening, (2 reading, (3 writing. Furthermore, the reading part is made of 4 components. Level 6 of this test implies a high degree of difficulty. This paper specifically looked on how to prepare effectively for participants to be able to work on the reading part in order to achieve best result. This article used the methods of literature review and observational study as well as field research and would also incorporate the author’s personal experience in taking the test into recommending strategies for doing the reading part in a level 6 HSK test. Finally, research suggested several techniques and tips that might assist participants in achieving maximum scores in handling the reading part of level 6 HSK test.

  13. Description of Cognitive and Competence Processes Involved in the Levels of Reading Comprehension in College Students

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    Charles Romel Yáñez Botello

    2013-12-01

    Full Text Available This is a descriptive research whose main objective was to describe the cognitive processes involved in reading and its relation to different levels of reading comprehension. For doing so, it was chosen a sample of 124 college students of Bogotá city. Participants- men and women between 16 and 30 years old- were studying first semester of psychology. The Evaluation Test for Reading Comprehension by Arenas (2007 was applied in order to describe cognitive operations. Moreover, results related to comprehension levels were analyzed through the Rasch Model. Besides, the Angof Methodology was used to specify the competence levels. It was concluded that there are five levels of reading comprehension. It must be said that most of the students were classified in the literal and inferential reading levels. Finally, the findings and limitations of the research were discussed.

  14. Circulating Levels of Irisin in Hypopituitary and Normal Subjects.

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    Lara Pena-Bello

    Full Text Available The recently identified myokine irisin conveys some of the benefits of exercise. Hypopituitarism with adult growth hormone deficiency (HP is a situation characterized by decreased GH secretion and an altered body composition.Our aim was to study the skeletal muscle hormone irisin in HP, and compare the results with a similar group of normal subjects.Seventeen HP patients and fifty-one normal subjects of similar age and sex were studied. The diagnosis of GH deficiency was confirmed by the presence of pituitary disease and a peak GH secretion below 3 μg/L after an insulin tolerance test. The patients were adequately treated for all pituitary hormone deficits, except for GH. Fasting serum irisin was measured with an enzyme immunoassay, and HOMA-IR, QUICKI and HOMA-β were calculated.Fasting irisin levels (ng/ml were similar in normal [208.42 (168.44-249.23] and HP patients [195.13 (178.44-241.44]. In the control group there were moderate significant positive correlations between irisin and BMI, waist circumference, leptin, fasting insulin, HOMA-IR, HOMA-β, triglycerides, and cholesterol. In the control group there were moderate significant negative correlations between irisin and IGF-I and QUICKI. In the hypopituitary group there were moderate significant positive correlations between irisin and body fat and HOMA-β.We found similar irisin levels in GH deficiency hypopituitary patients when compared with normal subjects. The correlation between irisin and adiposity related factors suggests that that in the case of this clinical model, irisin is regulated by adiposity and not by GH.

  15. Levels of Phonology Related to Reading and Writing in Middle Childhood.

    Science.gov (United States)

    Del Campo, Roxana; Buchanan, William R; Abbott, Robert D; Berninger, Virginia W

    2015-02-01

    The relationships of different levels of phonological processing (sounds in heard and spoken words for whole words, syllables, phonemes, and rimes) to multi-leveled functional reading or writing systems were studied. Participants in this cross-sectional study were students in fourth- grade (n=119, mean age 116.5 months) and sixth- grade (n=105, mean age 139.7 months). Multiple Indicators and Multiple Causes (MIMIC) modeling was used to analyze whether different levels of sound processing in heard and spoken words were correlated with each other and with multi-leveled reading or writing systems, and if so, which phonological skills explained unique variance in the reading or writing system. The models fit well at both grade levels for both reading and writing. All four phonological skills studied correlated significantly with each other and the latent factor for reading or writing. For reading, phonology for whole words and phonemes explained unique variance in fourth and sixth graders. For writing, at the fourth grade, only phonemes explained unique variance, but at the sixth grade level, syllables, phonemes, and rimes explained unique variance. Thus, the relationships between levels of phonology and reading were stable across grades 4 and 6, but developmental differences were observed in the relationships between levels of phonology and the leveled writing construct.

  16. Cytokine Levels in the Serum of Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Giulio Kleiner

    2013-01-01

    Full Text Available Growing knowledge about the cytokine network response has led to a better comprehension of mechanisms of pathologies and to the development of new treatments with biological drugs, able to block specific molecules of the immune response. Indeed, when the cytokine production is deregulated, diseases often occur. The understanding of the physiological mechanism of the cytokine network would be useful to better comprehend pathological conditions. Moreover, since the immune system and response change their properties with development, differences in patients' age should be taken into account, both in physiological and in pathological conditions. In this study, we analyzed the profile of 48 cytokines and chemokines in the serum of healthy subjects, comparing adults (≥18 years with young children and children (1–6 and 7–17 years. We found that a certain number of cytokines were not being produced in healthy subjects; others showed a constant serum level amongst the groups. Certain cytokines exhibited a downward or an upward trend with increasing age. The remaining cytokines were up- or downregulated in the group of the children with respect to the other groups. In conclusion, we drew some kinds of guidelines about the physiological production of cytokines and chemokines, underling the difference caused by aging.

  17. Deaf College Students' Mathematical Skills Relative to Morphological Knowledge, Reading Level, and Language Proficiency

    Science.gov (United States)

    Kelly, Ronald R.; Gaustad, Martha G.

    2007-01-01

    This study of deaf college students examined specific relationships between their mathematics performance and their assessed skills in reading, language, and English morphology. Simple regression analyses showed that deaf college students' language proficiency scores, reading grade level, and morphological knowledge regarding word segmentation and…

  18. Teacher cognition and the teaching of EFL reading at the Norwegian intermediate level

    OpenAIRE

    Gilje, Trine Mathiesen

    2011-01-01

    Master's thesis in Literacy studies The development of reading skills in English as a Foreign Language classrooms at the elementary level, the way in which teachers of English implement the LK06 learning objectives in reading, and the influence of teachers´attitudes, beliefs, and knowledge on their classroom practices and decisions.

  19. A Study on the Development of Reading Skills of the Students Having Difficulty in Reading: Enrichment Reading Program

    OpenAIRE

    Hayati AKYOL; Ahmet ÇAKIROĞLU; Hayriye Gül KURUYER

    2014-01-01

    The aim of this study is to improve the reading skills of the students having difficulty in reading through an enrichment reading program. The current study was conducted by means of one-subject research technique and between-subjects multiple-starting levels model belonging to this technique. The study was carried out with three participants from fifth grade. In order to collect data for the study, word recognition test, reading texts, Ekwall and Shanker reading inventory and reading compreh...

  20. [Reading poems to oneself affects emotional state and level of distraction].

    Science.gov (United States)

    Morita, Haruka; Sugamura, Genji

    2014-12-01

    Bibliotherapy has occasionally been used as a counseling technique. However, most reports are basically single-case studies and the psychological effect of this approach remains unclear. Two experiments using 96 healthy college volunteers were conducted to determine how the reading of emotionally positive, negative, or neutral passages affect one's mood and level of distraction. Study 1 revealed that participants felt more relaxed after reading positive poems with either personal or social content than after reading negativie ones, and they felt least refreshed and calm after reading negative poems with personal content. Study 2 showed that participants reported less depressed feelings, both after reading an excerpt from an explanatory leaflet and after a controlled rest period. These results were discussed in terms of the mood congruence effect. Future research may evaluate the effects of reading novels, manga, and life teachings on self-narratives and views of life in normal and clinical populations.

  1. The Effect of Reading from Screen on the 5th Grade Elementary Students' Level of Reading Comprehension on Informative and Narrative Type of Texts

    Science.gov (United States)

    Aydemir, Zeynep; Öztürk, Ergün; Horzum, M. Baris

    2013-01-01

    Digital medias that become popular through the development of technology have given a different functionality to read write experiences. The new conceptions such as reading from screen, e-literacy, digital text etc. have gained currency. The aim of the research was determined as the effect of reading from screen upon the levels of reading…

  2. Expanding the environment: gene × school-level SES interaction on reading comprehension.

    Science.gov (United States)

    Hart, Sara A; Soden, Brooke; Johnson, Wendy; Schatschneider, Christopher; Taylor, Jeanette

    2013-10-01

    Influential work has explored the role of family socioeconomic status (SES) as an environmental moderator of genetic and environmental influences on cognitive outcomes. This work has provided evidence that socioeconomic circumstances differentially impact the heritability of cognitive abilities, generally supporting the bioecological model in that genetic influences are greater at higher levels of family SES. The present work expanded consideration of the environment, using school-level SES as a moderator of reading comprehension. The sample included 577 pairs of twins from the Florida Twin Project on Reading, Behavior and Environment. Reading comprehension was measured by the Florida Comprehensive Achievement Test (FCAT) Reading in third or fourth grade. School-level SES was measured by the mean Free and Reduced Lunch Status (FRLS) of the schoolmates of the twins. The best-fitting univariate G × E moderation model indicated greater genetic influences on reading comprehension when fewer schoolmates qualified for FRLS (i.e., 'higher' school-level SES). There was also an indication of moderation of the shared environment; there were greater shared environmental influences on reading comprehension at higher school-level SES. The results supported the bioecological model; greater genetic variance was found in school environments in which student populations experienced less poverty. In general, 'higher' school-level SES allowed genetic and probably shared environmental variance to contribute as sources of individual differences in reading comprehension outcomes. Poverty suppresses these influences. © 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.

  3. Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations

    DEFF Research Database (Denmark)

    Hansen, Tine W; Thijs, Lutgarde; Li, Yan

    2010-01-01

    In previous studies, of which several were underpowered, the relation between cardiovascular outcome and blood pressure (BP) variability was inconsistent. We followed health outcomes in 8938 subjects (mean age: 53.0 years; 46.8% women) randomly recruited from 11 populations. At baseline, we asses...

  4. Reading problems in chronic aphasia.

    Science.gov (United States)

    Webb, W G; Love, R J

    1983-05-01

    Thirty-five aphasic subjects who were 1 year or longer post onset of brain injury were given a battery of reading tests which was composed of recognition and oral reading tests for letters, words, sentences, and paragraphs, and comprehension tests for sentences and paragraphs. Results indicated a residual reading disorder or alexia in all subjects, with comprehension tests producing the highest error rate, oral reading tests second, and then recognition tests. Reading ability was found to be related to overall language skill, level of education, and oral reading ability. Results are discussed in light of current theories of reading and future research needs.

  5. A Workshop Approach to Reading and Writing: Why Does It Work for Middle Level Learners?

    Science.gov (United States)

    Pollak, Judy P.

    1994-01-01

    Discusses the elements and activities in the workshop approach that motivate middle level students to begin to love to read and write. Examines the basic needs of students--survival, belonging, power, freedom, and fun. (RS)

  6. The reading grade level of common measures in child and adolescent clinical psychology.

    Science.gov (United States)

    Jensen, Scott A; Fabiano, Gregory A; Lopez-Williams, Andy; Chacko, Anil

    2006-09-01

    The purpose of this article is to provide easily accessible readability information for 49 parent- and 35 child- and adolescent-report measures commonly used by clinicians and researchers. There is a great deal of variability in reading ability required across measures. The majority of parent-report measures (65%) required reading ability above the 8th grade level. The average child-/adolescent-report measure required reading ability above the 6th grade level. Given the potential contribution of readability to a measure's reliability, validity, and overall utility, examining and accounting for readability should be a more common practice in test construction and administration.

  7. On the Accuracy of Iranian EFL Students' Reading Self-assessment and their Level of Reading Proficiency

    Directory of Open Access Journals (Sweden)

    Moein Shokr

    2015-10-01

    Full Text Available Reviewing the literature on self-assessment as an alternative method of assessment we find advocates claiming for the accuracy of the students’ self-assessments in general with little focus on their level of proficiency. With an eye on the students’ level of reading proficiency, the present study aimed at investigating the relationship between students’ reading self-assessment (as a formative and alternative method of assessment on the one hand, and teacher assessment (as a formative type of assessment as well as students’ final examination scores (as a summative and traditional method of assessment on the other. To this end, 65 students of Islamic Azad University- Tehran South Branch were selected to participate in this study. Initially, participants received PET test as pretest for assigning them into different levels of reading proficiency. Based upon the results of the pretest, participants were assigned to elementary and intermediate levels. Throughout the whole semester self-assessment questionnaire was employed for five times. Descriptive statistics and Pearson correlation were the data analysis techniques performed. The results of the study revealed a significant relationship between the intermediate learners’ self-ratings and teacher assessments; however, the results indicated no significant relationship between elementary learners’ self-assessments and teacher assessments. Also, the correlations between students’ self-assessments and their final examination scores were not significant for both levels. Therefore, given the teacher assessment as the yardstick, the accuracy of the intermediate levels and the inaccuracy of the elementary learners’ self-assessments could be concluded. Finally, the low correlation between the learners’ self-assessments and their scores on traditional final examination led the researcher to attribute it to the different nature of these two assessment types.

  8. Long-term language levels and reading skills in mandarin-speaking prelingually deaf children with cochlear implants.

    Science.gov (United States)

    Wu, Che-Ming; Chen, Yen-An; Chan, Kai-Chieh; Lee, Li-Ang; Hsu, Kuang-Hung; Lin, Bao-Guey; Liu, Tien-Chen

    2011-01-01

    The aim of this study was to document receptive and expressive language levels and reading skills achieved by Mandarin-speaking children who had received cochlear implants (CIs) and used them for 4.75-7.42 years. The effects of possible associated factors were also analyzed. Standardized Mandarin language and reading tests were administered to 39 prelingually deaf children with Nucleus 24 devices. The Mandarin Chinese version of the Peabody Picture Vocabulary Test was used to assess their receptive vocabulary knowledge and the Revised Primary School Language Assessment Test for their receptive and expressive language skills. The Graded Chinese Character Recognition Test was used to test their written word recognition ability and the Reading Comprehension Test for their reading comprehension ability. Raw scores from both language and reading measurements were compared to normative data of nor- mal-hearing children to obtain standard scores. The results showed that the mean standard score for receptive vocabulary measurement and the mean T scores for the receptive language, expressive language and total language measurement were all in the low-average range in comparison to the normative sample. In contrast, the mean T scores for word and text reading comprehension were almost the same as for their age-matched hearing counterparts. Among all children with CIs, 75.7% scored within or above the normal range of their age-matched hearing peers on receptive vocabulary measurement. For total language, Chinese word recognition and reading scores, 71.8, 77 and 82% of children with CIs were age appropriate, respectively. A strong correlation was found between language and reading skills. Age at implantation and sentence perception scores account for 37% of variance for total language outcome. Sentence perception scores and preimplantation residual hearing were revealed to be associated with the outcome of reading comprehension. We concluded that by using standard tests, the

  9. The Effects of Promoting Educational Level on the Development of Reading Comprehension Levels in Hearing-Impaired Students

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Sarmadi

    2011-09-01

    Full Text Available Background and Aim: Hearing-impaired students have some delays in learning language skills such as reading because of hearing loss. To study the effect of promoting educational level on the development of reading comprehension, the students of the 4th grade of elementary and last year guidance school were compared based on international test of reading literacy.Methods: The project was cross-sectional and the tool used was the international standard booklet of PIRLS 2001. Thirty-six students selected with moderately severe and severe hearing loss from the 4th grade of elementary and last year guidance school from Shahriar, Robatkarim, Karaj and Hashtgerd, Iran, exceptional schools. Comparative statistical analysis was performed using t-test.Results: The first level (focus on and retrieve explicity information showed a meaningful difference between the last year guidance school and the 4th grade of elementary students (p<0.05, but there were no significant differences in other levels, make straightforward information-interpret and integrate ideas-examine and evaluate content, (p> 0.05.Conclusion: Hearing-impaired students have difficulties in understanding in deep levels of reading despite promoting educational level. Thus, in making policies for special trainings, continuing the rehabilitation in guidance and high school levels to promote the complex levels of comprehension should be taken more into consideration.

  10. Neurobiological bases of reading comprehension: Insights from neuroimaging studies of word level and text level processing in skilled and impaired readers.

    Science.gov (United States)

    Landi, Nicole; Frost, Stephen J; Menc, W Einar; Sandak, Rebecca; Pugh, Kenneth R

    2013-04-01

    For accurate reading comprehension, readers must first learn to map letters to their corresponding speech sounds and meaning and then they must string the meanings of many words together to form a representation of the text. Furthermore, readers must master the complexities involved in parsing the relevant syntactic and pragmatic information necessary for accurate interpretation. Failure in this process can occur at multiple levels and cognitive neuroscience has been helpful in identifying the underlying causes of success and failure in reading single words and in reading comprehension. In general, neurobiological studies of skilled reading comprehension indicate a highly overlapping language circuit for single word reading, reading comprehension and listening comprehension with largely quantitative differences in a number of reading and language related areas. This paper reviews relevant research from studies employing neuroimaging techniques to study reading with a focus on the relationship between reading skill, single word reading, and text comprehension.

  11. Student's Readiness Level towards Implementation of paper 3 Subject History

    Directory of Open Access Journals (Sweden)

    Siti Aishah Suhaimi

    2017-11-01

    Full Text Available This study focuses on the student towards paper implementation 3 subject of history. This study use where survey research design as many as 50 from respondent 4 in School orchid, Cheras, chosen by gregarious sample and use instrument in obtaining quantitative data. This research using Social learning theory Albert Bandura, theory of constructivism and also Bloom's Taxonomy model. Data analyzed by using Excel Microsoft software 2010 (Statistic pack 2.0 (SPSS. Finding of correlation analysis show there is a significant relationship between student attitude approach with students’ knowledge towards paper of 3 history subject (r, =.846=, n=50, p<.0.5. Therefore, the paper 3 subject of history is seen as platform that is able to increase the understanding and performance of students in the general history often associated with subjects that are boring and hard to get better performance by students in examinations due to lack of interest, learning techniques are obsolete and inadequate learning.

  12. Assessing reading levels of health information: uses and limitations of flesch formula.

    Science.gov (United States)

    Jindal, Pranay; MacDermid, Joy C

    2017-01-01

    Written health information is commonly used by health-care professionals (HCPs) to inform and assess patients in clinical practice. With growing self-management of many health conditions and increased information seeking behavior among patients, there is a greater stress on HCPs and researchers to develop and implement readable and understandable health information. Readability formulas such as Flesch Reading Ease (FRE) and Flesch-Kincaid Reading Grade Level (FKRGL) are commonly used by researchers and HCPs to assess if health information is reading grade appropriate for patients. In this article, we critically analyze the role and credibility of Flesch formula in assessing the reading level of written health information. FRE and FKRGL assign a grade level by measuring semantic and syntactic difficulty. They serve as a simple tool that provides some information about the potential literacy difficulty of written health information. However, health information documents often involve complex medical words and may incorporate pictures and tables to improve the legibility. In their assessments, FRE and FKRGL do not take into account (1) document factors (layout, pictures and charts, color, font, spacing, legibility, and grammar), (2) person factors (education level, comprehension, health literacy, motivation, prior knowledge, information needs, anxiety levels), and (3) style of writing (cultural sensitivity, comprehensiveness, and appropriateness), and thus, inadequately assess reading level. New readability measures incorporate pictures and use complex algorithms to assess reading level but are only moderately used in health-care research and not in clinical practice. Future research needs to develop generic and disease-specific readability measures to evaluate comprehension of a written document based on individuals' literacy levels, cultural background, and knowledge of disease.

  13. A Definition of One Level of Achievement in the Reading and Writing of Spanish. Final Report.

    Science.gov (United States)

    Shawl, James Robert

    An operational definition of the standard for learner achievement at Level 2, with respect to the skills of reading and writing, was proposed for Spanish as one aspect of a research project. The method described, serving as the basis for articulation of level achievement, deals with general procedures, proposed operational definition of reading…

  14. An Analysis of the Text Complexity of Leveled Passages in Four Popular Classroom Reading Assessments

    Science.gov (United States)

    Toyama, Yukie; Hiebert, Elfrieda H.; Pearson, P. David

    2017-01-01

    This study investigated the complexity of leveled passages used in four classroom reading assessments. A total of 167 passages leveled for Grades 1-6 from these assessments were analyzed using four analytical tools of text complexity. More traditional, two-factor measures of text complexity found a general trend of fairly consistent across-grade…

  15. Subjectivity and Ideological Interpellation: An Althusserian Reading of Bozorg Alavi’s Her Eyes

    Directory of Open Access Journals (Sweden)

    Baktiar Sadjadi

    2017-12-01

    Full Text Available The present study seeks to critically investigate Bozorg Alavi’s celebrated Persian novel, Čašmhāyaš (Her Eyes, in terms of Louis Althusser’s concepts of ideology, interpellation and, most significantly, the subject/Subject model. Althusser developed the notion of ‘interpellation,’ that is the procedure through which individuals become subjects by what he called Ideological State Apparatuses. Accordingly, there exist ‘subjects’ and ‘the Subject’ at work precisely in the way ‘ideologies’ and ‘Ideology’ are present in the process of subjectivization. The subject is the individual who turns into being interpellated whereas the Subject is required by ideology. Bozorg Alavi’s Her Eyes, considered as chef-d’oeuvre in the realm of modern Persian realist fiction, portrays a protagonist who is wholeheartedly attached to his ideological Cause, a character who dedicated his whole life to socialist ideals. Alavi’s masterful depiction of the protagonist, Master Makan, and other major characters including Farangis in particular, demonstrates the way individuals are both consciously and unconsciously recruited by ideology, a process through which the subjects attempt to impersonate the Subject. Structurally, the ideological devotion in the protagonist, here to the communist Tudeh Party, entangles the subjects with a closed domain in a destructive manner that leads to their downfall.

  16. Developmental Relations between Reading and Writing at the Word, Sentence and Text Levels: A Latent Change Score Analysis.

    Science.gov (United States)

    Ahmed, Yusra; Wagner, Richard K; Lopez, Danielle

    2014-05-01

    Relations between reading and writing have been studied extensively but the less is known about the developmental nature of their interrelations. This study applied latent change score modeling to investigate longitudinal relations between reading and writing skills at the word, sentence and text levels. Latent change score models were used to compare unidirectional pathways (reading-to-writing and writing-to-reading) and bidirectional pathways in a test of nested models. Participants included 316 boys and girls who were assessed annually in grades 1 through 4. Measures of reading included pseudo-word decoding, sentence reading efficiency, oral reading fluency and passage comprehension. Measures of writing included spelling, a sentence combining task and writing prompts. Findings suggest that a reading-to-writing model better described the data for the word and text levels of language, but a bidirectional model best fit the data at the sentence level.

  17. Developmental Relations between Reading and Writing at the Word, Sentence and Text Levels: A Latent Change Score Analysis

    Science.gov (United States)

    Ahmed, Yusra; Wagner, Richard K.; Lopez, Danielle

    2013-01-01

    Relations between reading and writing have been studied extensively but the less is known about the developmental nature of their interrelations. This study applied latent change score modeling to investigate longitudinal relations between reading and writing skills at the word, sentence and text levels. Latent change score models were used to compare unidirectional pathways (reading-to-writing and writing-to-reading) and bidirectional pathways in a test of nested models. Participants included 316 boys and girls who were assessed annually in grades 1 through 4. Measures of reading included pseudo-word decoding, sentence reading efficiency, oral reading fluency and passage comprehension. Measures of writing included spelling, a sentence combining task and writing prompts. Findings suggest that a reading-to-writing model better described the data for the word and text levels of language, but a bidirectional model best fit the data at the sentence level. PMID:24954951

  18. Reading Ability and Reading Engagement in Older Adults With Glaucoma

    Science.gov (United States)

    Nguyen, Angeline M.; van Landingham, Suzanne W.; Massof, Robert W.; Rubin, Gary S.; Ramulu, Pradeep Y.

    2014-01-01

    Purpose. We evaluated the impact of glaucoma-related vision loss on reading ability and reading engagement in 10 reading activities. Methods. A total of 63 glaucoma patients and 59 glaucoma suspect controls self-rated their level of reading difficulty for 10 reading items, and responses were analyzed using Rasch analysis to determine reading ability. Reading engagement was assessed by asking subjects to report the number of days per week they engaged in each reading activity. Reading restriction was determined as a decrement in engagement. Results. Glaucoma subjects more often described greater reading difficulty than controls for all tasks except puzzles (P reading tasks involved puzzles, books, and finances, while the least difficult reading tasks involved notes, bills, and mail. In multivariable weighted least squares regression models of Rasch-estimated person measures of reading ability, less reading ability was found for glaucoma patients compared to controls (β = −1.60 logits, P reading ability was associated with more severe visual field (VF) loss (β = −0.68 logits per 5-dB decrement in better-eye VF mean deviation [MD], P reading on 18% fewer days (P = 0.003) and newspaper reading on 10% fewer days (P = 0.008). No statistically significant reading restriction was observed for other reading activities (P > 0.05). Conclusions. Glaucoma patients have less reading ability and engage less in a variety of different reading activities, particularly those requiring sustained reading. Future work should evaluate the mechanisms underlying reading disability in glaucoma to determine how patients can maintain reading ability and engagement. PMID:25052992

  19. Subjectivity

    Directory of Open Access Journals (Sweden)

    Jesús Vega Encabo

    2015-11-01

    Full Text Available In this paper, I claim that subjectivity is a way of being that is constituted through a set of practices in which the self is subject to the dangers of fictionalizing and plotting her life and self-image. I examine some ways of becoming subject through narratives and through theatrical performance before others. Through these practices, a real and active subjectivity is revealed, capable of self-knowledge and self-transformation. 

  20. Predicting Growth in Word Level Reading Skills in Children With Developmental Dyslexia Using an Object Rhyming Functional Neuroimaging Task.

    Science.gov (United States)

    Farris, Emily A; Ring, Jeremiah; Black, Jeffrey; Lyon, G Reid; Odegard, Timothy N

    2016-04-01

    An object rhyming task that does not require text reading and is suitable for younger children was used to predict gains in word level reading skills following an intensive 2-year reading intervention for children with developmental dyslexia. The task evoked activation in bilateral inferior frontal regions. Growth in untimed pseudoword reading was associated with increased pre-intervention activation of the left inferior frontal gyrus, and growth in timed word reading was associated with pre-intervention activation of the left and right inferior frontal gyri. These analyses help identify pre-intervention factors that facilitate reading skill improvements in children with developmental dyslexia.

  1. The Prediction of Reading Levels between Second and Third Grade Limited English Proficient Students in a Bilingual Program

    Science.gov (United States)

    Moses, Britani Creel

    2010-01-01

    The purpose of this study was to predict the third grade English reading TAKS scores while considering the same students' native language, Spanish, reading level as assessed by a state-approved reading assessment, the Evaluacion del desarrollo de la lectura (EDL), from the end of the second grade year. In addition, this study was been designed to…

  2. A read-out buffer prototype for ATLAS high level triggers

    CERN Document Server

    Calvet, D; Huet, M; Le Dû, P; Mandjavidze, I D; Mur, M

    2000-01-01

    Read-Out Buffers are critical components in the dataflow chain of the ATLAS Trigger/DAQ system. At up to 75 kHz, after each Level-1 trigger accept signal, these devices receive and store digitized data from groups of front-end electronic channels. Several Read-Out Buffers are grouped to form a Read-Out Buffer Complex that acts as a data server for the High Level Triggers selection algorithms and for the final data collection system. This paper describes a functional prototype of a Read-Out Buffer based on a custom made PCI mezzanine card that is designed to accept input data at up to 160 MB/s, to store up to 8 MB of data and to distribute data chunks at the desired request rate. We describe the hardware of the card that is based on an Intel I960 processor and CPLDs. We present the integration of several of these cards in a Read-Out Buffer Complex. We measure various performance figures and we discuss to which extent these can fulfill ATLAS needs. 5 Refs.

  3. Subjective impressions do not mirror online reading effort: concurrent EEG-eyetracking evidence from the reading of books and digital media

    National Research Council Canada - National Science Library

    Kretzschmar, Franziska; Pleimling, Dominique; Hosemann, Jana; Füssel, Stephan; Bornkessel-Schlesewsky, Ina; Schlesewsky, Matthias

    2013-01-01

    .... Young and elderly adults read short texts on three different reading devices: a paper page, an e-reader and a tablet computer and answered comprehension questions about them while their eye movements and EEG were recorded...

  4. Most American Academy of Orthopaedic Surgeons' online patient education material exceeds average patient reading level.

    Science.gov (United States)

    Eltorai, Adam E M; Sharma, Pranav; Wang, Jing; Daniels, Alan H

    2015-04-01

    Advancing health literacy has the potential to improve patient outcomes. The American Academy of Orthopaedic Surgeons' (AAOS) online patient education materials serve as a tool to improve health literacy for orthopaedic patients; however, it is unknown whether the materials currently meet the National Institutes of Health/American Medical Association's recommended sixth grade readability guidelines for health information or the mean US adult reading level of eighth grade. The purposes of this study were (1) to evaluate the mean grade level readability of online AAOS patient education materials; and (2) to determine what proportion of the online materials exceeded recommended (sixth grade) and mean US (eighth grade) reading level. Reading grade levels for 99.6% (260 of 261) of the online patient education entries from the AAOS were analyzed using the Flesch-Kincaid formula built into Microsoft Word software. Mean grade level readability of the AAOS patient education materials was 9.2 (SD ± 1.6). Two hundred fifty-one of the 260 articles (97%) had a readability score above the sixth grade level. The readability of the AAOS articles exceeded the sixth grade level by an average of 3.2 grade levels. Of the 260 articles, 210 (81%) had a readability score above the eighth grade level, which is the average reading level of US adults. Most of the online patient education materials from the AAOS had readability levels that are far too advanced for many patients to comprehend. Efforts to adjust the readability of online education materials to the needs of the audience may improve the health literacy of orthopaedic patients. Patient education materials can be made more comprehensible through use of simpler terms, shorter sentences, and the addition of pictures. More broadly, all health websites, not just those of the AAOS, should aspire to be comprehensible to the typical reader.

  5. A Study on the Development of Reading Skills of the Students Having Difficulty in Reading: Enrichment Reading Program

    Science.gov (United States)

    Akyol, Hayati; Çakiroglu, Ahmet; Kuruyer, Hayriye Gül

    2014-01-01

    The aim of this study is to improve the reading skills of the students having difficulty in reading through an enrichment reading program. The current study was conducted by means of one-subject research technique and between-subjects multiple-baseline levels model belonging to this technique. The study was carried out with three participants from…

  6. Using the Instructional Level as a Criterion to Target Reading Interventions

    Science.gov (United States)

    Parker, David C.; Burns, Matthew K.

    2014-01-01

    The instructional hierarchy offers a useful framework for targeting academic interventions. Within this framework, the accuracy with which a student reads might function as an indicator that the student should receive an intervention that focuses either on accuracy or on fluency. The current study examined whether the instructional level for…

  7. Lee y trabaja: Libro de lectura 2, nivel 1 (Read and Work: Reader 2, Level 1).

    Science.gov (United States)

    Martinez, Emiliano; and Others

    This reading textbook, the second of a series, is an anthology of stories designed to relate to the natural interest of the elementary school child. On this level the number of words to memorize is increased (on the average, four per unit) while at the same time, the study of word variants is introduced to begin analysis exercises based on the…

  8. Chitinase levels in the tears of subjects with ocular allergies.

    Science.gov (United States)

    Musumeci, Maria; Bellin, Milena; Maltese, Adriana; Aragona, Pasquale; Bucolo, Claudio; Musumeci, Salvatore

    2008-02-01

    Chitin is abundant in the structural coatings of fungi, insects, and parasitic nematodes. The host defense against chitin-containing pathogens includes production of chitinases. An acidic mammalian chitinase (AMCase) is produced in human epithelial cells of lower airways through a TH2-specific, interleukin-13-dependent pathway and appears to be associated with allergic asthma. The role of AMCase in allergic ocular pathologies has never been studied previously. Six patients with vernal keratoconjunctivitis (VKC), 7 patients with season allergic conjunctivitis (SAC), and 8 healthy controls (4 children and 4 adults) were enrolled in this study. AMCase activity was measured in tears, RNA was extracted from epithelial cells of the conjunctiva, and AMCase mRNA expression was evaluated by real-time polymerase chain reaction. AMCase activity was increased in patients affected by VKC (33.7 +/- 10.8 nmol/mL/h) and SAC (7.3 +/- 4.1 nmol/mL/h) compared with healthy controls (1.6 +/- 0.2 nmol/mL/h), and AMCase activity was higher in subjects with VKC (P = 0.0001). Receiver operating characteristic analysis showed that the sensitivity and specificity were 100%, addressing the use of AMCase assay in the biochemical diagnosis of VKC and SAC. AMCase mRNA was detected in epithelial cells of the conjunctiva, and the expression was significantly higher in VKC and SAC. AMCase may be an important mediator in the pathogenesis of TH2 inflammation eye diseases, suggesting a potential diagnostic and therapeutic target in these pathologies.

  9. Evaluation of reading performance in students from 3rd to 7th grade levels, with different text types.

    Science.gov (United States)

    Dellisa, Paula Roberta Rocha; Navas, Ana Luiza Gomes Pinto

    2013-01-01

    This study aimed to develop a reading profile of children from the third to seventh grade levels of elementary school. Fifty five children, between seven and 14 years of age, participated in the study. Four texts were previously developed by the researcher for reading evaluation - one composed of short words, another with long words, a third syntactically simple, and a syntactically complex text, which were read orally by the participants. After an evaluation of the results, the data were computed and the appropriate statistical analysis was applied. There was a gradual decrease in the mean time necessary for reading according to the participant's school grade level and a longer time for reading text containing long words in relation to texts containing short words. The same occurred for the reading of the syntactically complex text compared to the simple one, in all grade levels. It could be observed the higher rate of reading with the evolution of the grade levels, for each text, as well as a higher rate of reading for the text composed of short words in relation to the one with long words and for the syntactically simple text compared to the complex one. There was, in general, an increase in the percentage of words read correctly according to schooling. As for comprehension, very similar results were found, indicating good overall index of comprehension. It is important to develop reading instruments in relation to psycholinguistic parameters and cognitive demands, to better estimate the success in reading.

  10. Relationship of word- and sentence-level working memory to reading and writing in second, fourth, and sixth grade.

    Science.gov (United States)

    Berninger, Virginia W; Abbott, Robert D; Swanson, H Lee; Lovitt, Dan; Trivedi, Pam; Lin, Shin-Ju Cindy; Gould, Laura; Youngstrom, Marci; Shimada, Shirley; Amtmann, Dagmar

    2010-04-01

    The purpose of this study was to evaluate the contribution of working memory at the word and sentence levels of language to reading and writing outcomes. Measures of working memory at the word and sentence levels, reading and writing, were administered to 2nd (N = 122), 4th (N = 222), and 6th (N = 105) graders. Structural equation modeling was used to evaluate whether the 2 predictor working memory factors contributed unique variance beyond their shared covariance to each of 5 outcome factors: handwriting, spelling, composing, word reading, and reading comprehension. At each grade level, except for handwriting and composing in 6th grade, the word-level working memory factor contributed unique variance to each reading and writing outcome. The text-level working memory factor contributed unique variance to reading comprehension in 4th and 6th grade. The clinical significance of these findings for assessment and intervention is discussed.

  11. Levels of Phonology Related to Reading and Writing in Middle Childhood

    Science.gov (United States)

    Del Campo, Roxana; Buchanan, William R.; Abbott, Robert D.; Berninger, Virginia W.

    2015-01-01

    The relationships of different levels of phonological processing (sounds in heard and spoken words for whole words, syllables, phonemes, and rimes) to multi-leveled functional reading or writing systems were studied. Participants in this cross-sectional study were students in fourth-grade (n = 119, mean age 116.5 months) and sixth-grade (n = 105,…

  12. READING THEORIES AND READING COMPREHENSION

    OpenAIRE

    Maria Novary Ngabut

    2015-01-01

    In this article several reading theories in their relations to reading comprehension teachers and lecturers of English need to know are reviewed. At the theory level, three other Models of Reading, namely Bottom-Up, Top-Down, and Interactive are previously discussed to the Schema Theory. In reviewing the reading comprehension, the history of reading instruction, types and purposes of reading, and cognitive reading skills are discussed. Finally, it reviews six variables involved in the compreh...

  13. Qualitative descriptions of error recovery patterns across reading level and sentence type: an eye movement analysis.

    Science.gov (United States)

    Fletcher, J

    1991-11-01

    Purposes of the present study included describing a variety of error recovery patterns based on eye movement (EM) measures of sentence parsing across reading level and error type. A qualitative pattern analysis of EM mappings was completed for students with reading disabilities (n = 10) and nondisabled students (n = 10) who were parsing control and erred sentences. Independent variables included error type (syntactically ambiguous, semantically anomalous, and control sentences) and reading proficiency level. Dependent variables consisted of seven eye movement measures. Chi-square analyses were performed to examine group differences across frequencies per pattern. Results suggest that the error recovery strategies deployed by both groups were similar in pattern and frequency; patterns were largely organized, strategic, and efficient, as predicted. Evidence for seven newly defined strategies was found, with indications of multiple strategies within sentences by both groups. Strategies tended to be error "reanalysis" (vs. "recovery") heuristics, in that readers from both groups used regressions to reanalyze regions of inconsistency rather than regions of disambiguation. Earlier conclusions regarding disorganized processing and individual differences among adolescents with reading disabilities are discussed.

  14. Subjectively homogeneous noise over written text as a tool to investigate the perceptual mechanisms involved in reading.

    Science.gov (United States)

    Poirier, Frédéric J A M; Gosselin, Frédéric; Arguin, Martin

    2013-09-24

    In an effort to understand the factors influencing text legibility in natural reading, we adapted the visual spread method (Poirier, Gosselin, & Arguin, 2008) to natural text. Stimuli were sentences conforming to MNREAD standards (Legge, Ross, Luebker, & LaMay 1989) mixed with dynamic probabilistic noise-i.e., each pixel in the image is associated with a probability that its polarity is inverted on a given refresh cycle of the display screen. Noise level varied continuously over the image as initially determined by Gaussian-filtered noise. Participants adjusted noise levels in the text using the mouse until the text appeared homogenously noisy. We assume that participants increased (or decreased) noise at locations where stimulus features were easy (or difficult) to encode and thus that local noise settings correlate with legibility. Data from 11 participants and 30 sentences revealed interesting effects, demonstrating the validity of the method for assessing the impact of various factors on noise resistance in natural text. For example, participants increased noise over (a) spaces and adjacent letters, (b) the second half of words, (c) words with more orthographic neighbors but fewer phonological neighbors, (d) less useful word types, (e) less complex letters, and (f) diagnostic letters (a novel metric). Our observations also offer significant insights on constraints acting upon letter identification as well as on higher-level processes that are involved in reading.

  15. Longitudinal Relationships of Levels of Language in Writing and between Writing and Reading in Grades 1 to 7

    Science.gov (United States)

    Abbott, Robert D.; Berninger, Virginia W.; Fayol, Michel

    2010-01-01

    Longitudinal structural equation modeling was used to evaluate longitudinal relationships across adjacent grade levels 1 to 7 for levels of language in writing (Model 1, subword letter writing, word spelling, and text composing) or writing and reading (Model 2, subword letter writing and word spelling and reading; Model 3, word spelling and…

  16. Do the Low Levels of Reading Course Material Continue? An Examination in a Forensic Psychology Graduate Program

    Science.gov (United States)

    Clump, Michael A.; Doll, Jason

    2007-01-01

    Clump, Bauer, and Bradley (2004) and Burchfield and Sappington (2000) previously found extremely low levels of reading in undergraduate psychology courses. The current study investigated whether these low levels of reading are also found with graduate students, or if this value is altered by only investigating individuals who show continued…

  17. Relationship of Word- and Sentence-Level Working Memory to Reading and Writing in Second, Fourth, and Sixth Grade

    Science.gov (United States)

    Berninger, Virginia W.; Abbott, Robert D.; Swanson, H. Lee; Lovitt, Dan; Trivedi, Pam; Lin, Shin-Ju; Gould, Laura; Youngstrom, Marci; Shimada, Shirley; Amtmann, Dagmar

    2010-01-01

    Purpose: The purpose of this study was to evaluate the contribution of working memory at the word and sentence levels of language to reading and writing outcomes. Method: Measures of working memory at the word and sentence levels, reading and writing, were administered to 2nd (N = 122), 4th (N = 222), and 6th (N = 105) graders. Structural equation…

  18. Understanding the Relative Contributions of Lower-Level Word Processes, Higher-Level Processes, and Working Memory to Reading Comprehension Performance in Proficient Adult Readers

    Science.gov (United States)

    Hannon, Brenda

    2012-01-01

    Although a considerable amount of evidence has been amassed regarding the contributions of lower-level word processes, higher-level processes, and working memory to reading comprehension, little is known about the relationships among these sources of individual differences or their relative contributions to reading comprehension performance. This…

  19. Polish Adult Reading Test (PART) - construction of Polish test for estimating the level of premorbid intelligence in schizophrenia.

    Science.gov (United States)

    Karakuła-Juchnowicz, Hanna; Stecka, Mariola

    2017-08-29

    In view of unavailability in Poland of the standardized methods to measure PIQ, the aim of the work was to develop a Polish test to assess the premorbid level of intelligence - PART(Polish AdultReading Test) and to measureits psychometric properties, such as validity, reliability as well as standardization in the group of schizophrenia patients. The principles of PART construction were based on the idea of popular worldwide National Adult Reading Test by Hazel Nelson. The research comprised a group of 122 subjects (65 schizophrenia patients and 57 healthy people), aged 18-60 years, matched for age and gender. PART appears to be a method with high internal consistency and reliability measured by test-retest, inter-rater reliability, and the method with acceptable diagnostic and prognostic validity. The standardized procedures of PART have been investigated and described. Considering the psychometric values of PART and a short time of its performance, the test may be a useful diagnostic instrument in the assessment of premorbid level of intelligence in a group of schizophrenic patients.

  20. An Analysis of the Critical Reading Levels of Pre-Service Turkish and Literature Teachers

    Science.gov (United States)

    Maltepe, Sadet

    2016-01-01

    Problem Statement: Critical reading refers to individuals' thinking about what they read, assessing what they have read, and using their own judgment about what they have read. In order to teach critical reading skills to students, a teacher is expected to have knowledge about text selection, use of appropriate methods, preparation of functional…

  1. Quantifying hemodynamic refractory bold effects in normal subjects at the single-subject level using an inverse logit fitting procedure.

    Science.gov (United States)

    Descamps, Benedicte; Vandemaele, Pieter; Reyngoudt, Harmen; Deblaere, Karel; Leybaert, Luc; Paemeleire, Koen; Achten, Eric

    2012-03-01

    To evaluate whether hemodynamic refractory effects provoked by repeated visual stimulation can be detected and quantified at the single-subject level using a recently described hemodynamic response function (HRF) fitting algorithm. Hemodynamic refractory effects were induced with an easily applicable functional MRI (fMRI) paradigm. A fitting method with inverse logit (IL) functions was applied to quantify net HRFs at the single-subject level with three interstimulus intervals (ISI; 1, 2, and 6 s). The model yielded amplitude, latencies, and width for each HRF. HRF fitting was possible in 44 of 51 healthy volunteers, with excellent goodness-of-fit (R(2) = 0.9745 ± 0.0241). Refractory effects were most pronounced for the 1-s ISI (P < 0.001) and had nearly disappeared for the 6-s ISI. Quantifying refractory effects in individuals was possible in 86.3% of normal subjects using the IL fitting algorithm. This setup may be suitable to explore such effects in individual patients. Copyright © 2011 Wiley Periodicals, Inc.

  2. Reading Comprehension, Working Memory and Higher-Level Language Skills in Children with SLI and/or Dyslexia

    Science.gov (United States)

    Wong, Anita M.-Y.; Ho, Connie S.-H.; Au, Terry K.-F.; McBride, Catherine; Ng, Ashley K.-H.; Yip, Lesley P.-W.; Lam, Catherine C.-C.

    2017-01-01

    This study examined (1) whether working memory and higher-level languages skills--inferencing and comprehension monitoring--accounted for individual differences among Chinese children in Chinese reading comprehension, after controlling for age, Chinese word reading and oral language skills, and (2) whether children with specific language…

  3. Effect of Posttraumatic Stress on Study Time in a Task Measuring Four Component Processes Underlying Text-Level Reading

    Science.gov (United States)

    Sullivan, Michael P.; Griffiths, Gina G.; Sohlberg, Mckay Moore

    2014-01-01

    Purpose: To investigate the effect of combat-related posttraumatic stress disorder (PTSD) on 4 components underlying text-level reading comprehension. Method: A group of 17 veterans with PTSD and 17 matched control participants took part. An experimental task required participants to read and study 3-sentence paragraphs describing semantic…

  4. Factors in the development of higher levels of reading literacy: Argumentation skills in educational practice

    Directory of Open Access Journals (Sweden)

    Branković Marija

    2013-01-01

    Full Text Available The highest levels of reading literacy, as defined within PISA study, include the ability to use various cognitive skills, with argumentative skills being one of the most important among them. In the present study our goal was to reveal some of the factors that influence the development of argumentative skills in Serbian schools. We investigated the extent to which argumentative skills are required in PISA reading literacy tasks, as well as the specific difficulties our students have faced on these tasks, through an analysis of student performance. We also conducted an analysis of the educational practice - by doing in-depth interviews with teachers and content analysis of students' textbooks. The results revealed that: 1 Argumentations skills are an important requirement within PISA tasks; 2 Serbian students are mostly successful at basic tasks of recognizing arguments or providing arguments for the given position; they face difficulties answering the tasks which require precise formulation of relevant arguments as well as those demanding meta-cognitive skills (e.g. recognizing persuasive strategies in the given text. Their performance is particularly poor on tasks requiring the combination of information from different sources or information presented in different formats (text, tables, or graphs; 3 There is a significant gap between the requirements for argumentation skills our students usually encounter and PISA reading literacy tasks. In this paper we discuss some of the difficulties and obstacles to encouraging the development of argumentative thinking.

  5. An efficient and scalable graph modeling approach for capturing information at different levels in next generation sequencing reads.

    Science.gov (United States)

    Warnke, Julia D; Ali, Hesham H

    2013-01-01

    Next generation sequencing technologies have greatly advanced many research areas of the biomedical sciences through their capability to generate massive amounts of genetic information at unprecedented rates. The advent of next generation sequencing has led to the development of numerous computational tools to analyze and assemble the millions to billions of short sequencing reads produced by these technologies. While these tools filled an important gap, current approaches for storing, processing, and analyzing short read datasets generally have remained simple and lack the complexity needed to efficiently model the produced reads and assemble them correctly. Previously, we presented an overlap graph coarsening scheme for modeling read overlap relationships on multiple levels. Most current read assembly and analysis approaches use a single graph or set of clusters to represent the relationships among a read dataset. Instead, we use a series of graphs to represent the reads and their overlap relationships across a spectrum of information granularity. At each information level our algorithm is capable of generating clusters of reads from the reduced graph, forming an integrated graph modeling and clustering approach for read analysis and assembly. Previously we applied our algorithm to simulated and real 454 datasets to assess its ability to efficiently model and cluster next generation sequencing data. In this paper we extend our algorithm to large simulated and real Illumina datasets to demonstrate that our algorithm is practical for both sequencing technologies. Our overlap graph theoretic algorithm is able to model next generation sequencing reads at various levels of granularity through the process of graph coarsening. Additionally, our model allows for efficient representation of the read overlap relationships, is scalable for large datasets, and is practical for both Illumina and 454 sequencing technologies.

  6. Negotiation between peers: strategic device for a reading and writing program at the university level

    Directory of Open Access Journals (Sweden)

    Estela Ines Moyano

    2016-09-01

    Full Text Available The following paper focuses on the description and exemplification of a device which is the core of the Academic Reading and Writing Program (PROLEA, for its acronym in Spanish conducting at University of Flores (UFLO: the “negotiation between peers” or “negotiation between teaching partners”. The Program design is based on the Sydney School's developments in Systemic Functional Linguistics. The negotiation between peers comprises the work between a professor on academic and professional literacies, who is a member of the Program, and the professors of each of the specific subjects involved. In order to successfully implement this modality, the realization of the negotiation between peers is necessary. This device entails a series of agreements between the professors involved about the teaching of the curricula contents through reading and writing tasks. First in this paper, the negotiation between peers is characterized, and its function and value in the Program are highlighted; second, two scenarios of application are presented in order to show the device contribution as well as its difficulties and the way of resolution of the problems found.

  7. Negotiation between peers: strategic device for a reading and writing program at the university level

    Directory of Open Access Journals (Sweden)

    Estela Ines Moyano

    2016-09-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2016v69n3p157 The following paper focuses on the description and exemplification of a device which is the core of the Academic Reading and Writing Program (PROLEA, for its acronym in Spanish conducting at University of Flores (UFLO: the “negotiation between peers” or “negotiation between teaching partners”. The Program design is based on the Sydney School's developments in Systemic Functional Linguistics. The negotiation between peers comprises the work between a professor on academic and professional literacies, who is a member of the Program, and the professors of each of the specific subjects involved. In order to successfully implement this modality, the realization of the negotiation between peers is necessary. This device entails a series of agreements between the professors involved about the teaching of the curricula contents through reading and writing tasks. First in this paper, the negotiation between peers is characterized, and its function and value in the Program are highlighted; second, two scenarios of application are presented in order to show the device contribution as well as its difficulties and the way of resolution of the problems found.

  8. Muon Identification with the ATLAS Tile Calorimeter Read-Out Driver for Level-2 Trigger Purposes

    CERN Document Server

    Ruiz-Martinez, A

    2008-01-01

    The Hadronic Tile Calorimeter (TileCal) at the ATLAS experiment is a detector made out of iron as passive medium and plastic scintillating tiles as active medium. The light produced by the particles is converted to electrical signals which are digitized in the front-end electronics and sent to the back-end system. The main element of the back-end electronics are the VME 9U Read-Out Driver (ROD) boards, responsible of data management, processing and transmission. A total of 32 ROD boards, placed in the data acquisition chain between Level-1 and Level-2 trigger, are needed to read out the whole calorimeter. They are equipped with fixed-point Digital Signal Processors (DSPs) that apply online algorithms on the incoming raw data. Although the main purpose of TileCal is to measure the energy and direction of the hadronic jets, taking advantage of its projective segmentation soft muons not triggered at Level-1 (with pT<5 GeV) can be recovered. A TileCal standalone muon identification algorithm is presented and i...

  9. Fasting Lipoprotein Lipase Protein Levels Can Predict a Postmeal Increment of Triglyceride Levels in Fasting Normohypertriglyceridemic Subjects.

    Science.gov (United States)

    Tsuzaki, Kokoro; Kotani, Kazuhiko; Yamada, Kazunori; Sakane, Naoki

    2016-09-01

    Although a postprandial increment in triglyceride (TG) levels is considered to be a risk factor for atherogenesis, tests (e.g., fat load) to assess postprandial changes in TG levels cannot be easily applied to clinical practice. Therefore, fasting markers that predict postprandial TG states are needed to be developed. One current candidate is lipoprotein lipase (LPL) protein, a molecule that hydrides TGs. This study investigated whether fasting LPL levels could predict postprandial TG levels. A total of 17 subjects (11 men, 6 women, mean age 52 ± 11 years) with normotriglyceridemia during fasting underwent the meal test. Several fasting parameters, including LPL, were measured for the area under the curve of postprandial TGs (AUC-TG). The subjects' mean fasting TG level was 1.30 mmol/l, and their mean LPL level was 41.6 ng/ml. The subjects' TG levels increased after loading (they peaked after two postprandial hours). Stepwise multiple regression analysis demonstrated that fasting TG levels were a predictor of the AUC-TG. In addition, fasting LPL mass levels were found to be a predictor of the AUC-TG (β = 0.65, P fasting TG levels. Fasting LPL levels may be useful to predict postprandial TG increment in this population. © 2015 Wiley Periodicals, Inc.

  10. Serum lipid resistance to oxidation and uric acid levels in subjects with Down's syndrome.

    Science.gov (United States)

    Nagyová, A; Sustrová, M; Raslová, K

    2000-01-01

    In subjects with Down's syndrome (DS) increased oxidative stress and consequent oxidative cell damage have been reported. The aim of this study was to assess whether the excessive production of free oxygen radicals in these subjects can affect the copper-induced lipid oxidation resistance measured in fresh whole serum. Since a significant elevation of serum uric acid levels, which is an efficient hydrophilic antioxidant, has been repeatedly reported in subjects with DS, we studied the association between increased serum uric acid levels and lipid resistance to oxidation measured directly in serum samples by monitoring the change in absorbance at 234 nm. The group of subjects with Down's syndrome consisted of 25 individuals (aged 18+/-5 years). Control group included brothers and sisters of subjects with DS (n = 25, aged 17+/-7 years). In subjects with DS, the serum lipid resistance to oxidation (lag time) was significantly higher than in controls (puric acid levels was observed (puric acid concentration was found in subjects with DS (r = 0.48, puric acid levels repeatedly observed in subjects with DS may be associated with an enhanced resistance of serum lipids to oxidation which is thought to play an important role in the atherogenic process.

  11. Comics as a Literary-Didactic Method and Their Use for Reducing Gender Differences in Reading Literacy at the Primary Level of Education

    Science.gov (United States)

    Kerneža, Maja; Košir, Katja

    2016-01-01

    The aim of the present study was to examine the effect of the systematic use of comics as a literary-didactic method to reduce gender differences in reading literacy and reading motivation at the primary level of education. It was assumed that the use of comics would have a positive effect on pupils' reading literacy and reading motivation, while…

  12. Good/Bad Girls Read Together: Pre-Adolescent Girls' Co-Authorship of Feminine Subject Positions during a Shared Reading Event.

    Science.gov (United States)

    Enciso, Patricia E.

    1998-01-01

    Discusses reading with pre-teens Francine Pascal's "Sweet Valley Twins: Best Friends," one of a series of pre-romance novels featuring identical twin sisters. Interviews six girls using the Symbolic Representation Interview (SRI) about the good girl/bad girl dichotomy in novels and other media. Provides comments by Tom Romano and Diana Mitchell.…

  13. Desempenhos em leitura nas séries finais de ciclo = Performance in reading in the final grades of the primary level schooling

    Directory of Open Access Journals (Sweden)

    Cristiane Malinoski Pianaro Angelo

    2008-07-01

    Full Text Available O artigo discute as práticas leitoras no ensino fundamental, tendo-se como pressuposto a concepção interacionista-discursiva de leitura. Objetiva-se apresentar diagnóstico da competência leitora de alunos em séries finais de ciclo, atendidos no município de Irati, Estado do Paraná, a fim de contribuir com uma reflexão crítica acerca daqualidade de leitura desses alunos. Para tanto, descrevem-se e analisam-se questionários de leitura aplicados a alunos de 4ª e 8ª séries do ensino fundamental. Os resultados apontam que a maioria dos alunos, principalmente os de classes sociais menos favorecidas, nãoapresenta bom desempenho na leitura. A constatação dessa realidade é preocupante, pois o mau desempenho na leitura interfere em todas as atividades curriculares, comprometendo a produção textual e o estabelecimento de relações entre os conteúdos aprendidos.Current research discusses reading practices in primary education through the discursive and interaction concept of reading. A diagnosis of reading competence of students in the final grades of the primary level schooling, in the municipality of Irati,Paraná State, Brazil, is provided so that a critical reflection on the students’ reading quality may be undertaken. Questionnaires on reading applied to students enrolled in the fourth and in the eight grade of primary education are described and analyzed. Results show that most students, mainly those from the lower social classes, do not achieve good performance in reading. This finding is the object of deep concern since bad performance in reading interferes in all curricular activities, impairs textual production and the establishment of relations between the contents of the subject matters.

  14. The Influence of Subject Knowledge and Second Language Proficiency on the Reading Comprehension of Scientific and Technical Discourse.

    Science.gov (United States)

    Chung, Tim; Berry, Vivien

    2000-01-01

    Examined the effect of background knowledge and second language proficiency in relation to two sets of specific reading materials. One came from an IELTS reading module related to science and technology; the other was from a highly-specific popular science text. Results showed that both language proficiency and background knowledge predicted…

  15. Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype.

    Directory of Open Access Journals (Sweden)

    Kirsten B Holven

    Full Text Available Epidemiological studies have shown that low plasma levels of high-density lipoprotein (HDL cholesterol are associated with increased risk of cardiovascular disease, but the mechanisms for the possible atheroprotective effects of HDL cholesterol have still not been fully clarified, in particular in relation to clinical studies.To examine the inflammatory, anti-oxidative and metabolic phenotype of subjects with low plasma HDL cholesterol levels.Fifteen subjects with low HDL cholesterol levels (eleven males and four females and 19 subjects with high HDL (three males and 16 females were recruited. Low HDL cholesterol was defined as ≤10th age/sex specific percentile and high HDL-C was defined as ≥90 age/sex specific percentile. Inflammatory markers in circulation and PBMC gene expression of cholesterol efflux mediators were measured. Our main findings were: (i subjects with low plasma HDL cholesterol levels were characterized by increased plasma levels of CRP, MMP-9, neopterin, CXCL16 and ICAM-1 as well as low plasma levels of adiponectin, suggesting an inflammatory phenotype; (ii these individuals also had reduced paraoxonase (PON1 activity in plasma and PON2 gene expression in peripheral blood mononuclear cells (PBMC accompanied by increased plasma levels of oxidized LDL suggesting decreased anti-oxidative capacity; and (iii PBMC from low HDL subjects also had decreased mRNA levels of ABCA1 and ABCG1, suggesting impaired reverse cholesterol transport.Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype that could contribute to the increased risk of atherosclerotic disorders in these subjects with low HDL levels.

  16. The Impact of Task-based Activities on the Reading Skill of Iranian EFL Young Learners at the Beginner Level

    Directory of Open Access Journals (Sweden)

    Arshya Keyvanfar

    2009-05-01

    Full Text Available Task-based learning and teaching in the realm of teaching young learners is still considered an adventure since very few experimental studies to date have tackled its applicability in that age group. The present research was an attempt to find out whether using task-based reading activities has any impact on the development of text comprehension in Iranian young learners studying English as a foreign language at the beginner level. Two groups of 25 students, aged 11 to 13, were the participants of the study. Through a reading pretest, it was ensured that the two groups were at the same level and belonged to the same population in terms of the reading skill. Having instructed the experimental group with four task types and the control group with classical reading activities, the researcher compared the reading performance of the two groups through a t-test which, not surprisingly, manifested the better performance of the experimental group. A follow-up reading test also showed that the experimental group still enjoyed a higher level of reading skill after one month. Furthermore, the scores gained from the four task types were compared and it was concluded that the students performed better in tasks which involved creativity and gave them the experience of playing.

  17. Subjective and Objective Assessment of Mathematics Anxiety Levels among College Students

    OpenAIRE

    Baloğlu, Mustafa

    2018-01-01

    The study investigated the relationship between college students’ subjective and objective assessment of mathematics anxiety levels. Students rated their general and current mathematics anxiety levels, mathematical ability levels, and confidence in doing mathematics. The Revised Mathematics Anxiety Rating Scale was used as an objective measure of their mathematics anxiety levels. Participants were 559 students, 406 (72.6%) women and 151 (27.0%) men. Results showed that perceived general mathe...

  18. Elevated blood lead levels and reading readiness at the start of kindergarten.

    Science.gov (United States)

    McLaine, Pat; Navas-Acien, Ana; Lee, Rebecca; Simon, Peter; Diener-West, Marie; Agnew, Jacqueline

    2013-06-01

    To evaluate the relationship between blood lead levels (BLLs) and reading readiness at kindergarten entry, an early marker of school performance, in a diverse urban school population. Kindergarten reading readiness test scores for children attending public kindergarten in Providence, Rhode Island, were linked to state health department records of blood lead testing by using individual identifiers. The study population (N = 3406) was 59% Hispanic. For each child, the geometric mean BLL was estimated by using all previously reported BLLs. Analyses were adjusted for gender, age, year enrolled, race, child language, and free/reduced lunch status as a measure of socioeconomic status. The median geometric mean BLL was 4.2 µg/dL; 20% of children had at least 1 venous BLL ≥10 µg/dL. Compared with children with BLLs readiness were 1.21 (1.19 to 1.23) and 1.56 (1.51 to 1.60) for children with BLLs of 5 to 9 and ≥10 µg/dL, respectively. On average, reading readiness scores decreased by 4.5 (95% CI: -2.9 to -6.2) and 10.0 (95% CI: -7.0 to -13.3) points for children with BLLs of 5 to 9 and ≥10 µg/dL, respectively, compared with BLLs readiness at kindergarten entry. The high prevalence of elevated BLLs warrants additional investigation in other high-risk US populations. Results suggest benefits from additional collaboration between public health, public education, and community data providers.

  19. An Examination of Student- and Across-Level Mediation Mechanisms Accounting for Gender Differences in Reading Performance: A Multilevel Analysis of Reading Engagement

    Science.gov (United States)

    Mak, Soi-kei; Cheung, Kwok-cheung; Soh, Kaycheng; Sit, Pou-seong; Ieong, Man-kai

    2017-01-01

    Enjoyment of reading, diversity of reading and metacognitive awareness of reading strategies are cognitive and affective variables pertaining to three facets of reading engagement for students to read happily, widely and skilfully. These have been found to be related to effectiveness in reading instruction. They together form a focus for this…

  20. Integration of parafoveal orthographic information during foveal word reading: beyond the sub-lexical level?

    Science.gov (United States)

    Snell, Joshua; Vitu, Françoise; Grainger, Jonathan

    2017-10-01

    Prior research has shown that processing of a given target word is facilitated by the simultaneous presentation of orthographically related stimuli in the parafovea. Here we investigate the nature of such spatial integration processes by presenting orthographic neighbours of target words in the parafovea, considering that neighbours have been shown to inhibit, rather than facilitate, recognition of target words in foveal masked priming research. In Experiment 1, we used the gaze-contingent boundary paradigm to manipulate the parafoveal information subjects received while they fixated a target word within a sentence. In Experiment 2, we used the Flanking Letters Lexical Decision paradigm to manipulate parafoveal information while subjects read isolated words. Parafoveal words were either a higher-frequency orthographic neighbour of targets words (e.g., blue-blur) or a high-frequency unrelated word (e.g., hand-blur). We found that parafoveal orthographic neighbours facilitated, rather than inhibited, processing of the target. Thus, the present findings provide further evidence that orthographic information is integrated across multiple words and suggest that either the integration process does not enable simultaneous access to those words' lexical representations, or that lexical representations activated by spatially distinct stimuli do not compete for recognition.

  1. Planning of questions for various level of reading of textbooks for early grade students

    Directory of Open Access Journals (Sweden)

    Edita Haxhijaha

    2015-07-01

    Full Text Available During the entire history of education, questioning has been one of the usual techniques of teaching. Despite all the changes in the education theory and technology, this technique continues to be usual, because it is an efficient tool to increase learning. Questioning is an interactive relation, which enlivens the conversation, by giving continuity to the finding of final result. Questioning should be assessed as a technique, which gives high results, when it is managed successfully and with attention towards the teacher, playing meanwhile an important role during the learning of students. Through various planed activities, I tried to influence teachers in order to plan as many questions as possible, for the development of student’s critical thinking. Taking into account the development of further activities I focused in the results extracted from the data gained from the observation of teachers, target group, consultations with teachers, and took into consideration various literature which considered this issue. This research included five teachers that teach in classes 1-5, in the ELSS “Emin Duraku” in Prizren/Kosovo. Observation consisted of two periods. Results of the first period of observation showed that while preparing the teaching work, specifically planning of questions I noticed that a big number were direct questions with a low level of thinking. The research continued by maintaining the target group focused where important discussions were held about the importance of planning the questions of different levels that helped students to understand what they read and also contributed to the increasing of their interest for reading-understanding of various school texts. Then the second period of observation was conducted. Results showed that there were differences in the planning of questions by teachers, compared to the results of the first period of observation. Conclusions of this operational research showed that students can

  2. Haplotypes of vitamin D receptor modulate the circulating levels of lead in exposed subjects

    Energy Technology Data Exchange (ETDEWEB)

    Rezende, Vania B. [State University of Campinas, Department of Pharmacology, Faculty of Medical Sciences, Campinas, SP (Brazil); Barbosa, Fernando [University of Sao Paulo, Department of Clinical, Toxicological and Food Science Analysis, Faculty of Pharmaceutical Sciences of Ribeirao Preto, Ribeirao Preto, SP (Brazil); Montenegro, Marcelo F.; Sandrim, Valeria C.; Tanus-Santos, Jose E. [University of Sao Paulo, Ribeirao Preto, Department of Pharmacology, Faculty of Medicine of Ribeirao Preto, Ribeirao Preto, SP (Brazil); Gerlach, Raquel F. [University of Sao Paulo, Department of Morphology, Estomatology and Physiology, Dental School of Ribeirao Preto, Ribeirao Preto, SP (Brazil)

    2008-01-15

    Genetic factors influence whole blood lead (Pb-B) concentrations in lead exposed subjects. This study aimed at examining the combined effects (haplotype analysis) of three polymorphisms (BsmI, ApaI and FokI) in vitamin D receptor (VDR) gene on Pb-B and on the concentrations of lead in plasma (Pb-P), which is more relevant to lead toxicity, in 150 environmentally exposed subjects. Genotypes were determined by RFLP, and Pb-P and Pb-B were determined by inductively coupled plasma mass spectrometry and by graphite furnace atomic absorption spectrometry, respectively. Subjects with the bb (BsmI polymorphism) or ff (FokI polymorphism) genotypes have lower B-Pb than subjects in the other genotype groups. Subjects with the aa (ApaI polymorphism) or ff genotypes have lower P-Pb than subjects in the other genotype groups. Lower Pb-P, Pb-B, and %Pb-P/Pb-B levels were found in subjects with the haplotype combining the a, b, and f alleles for the ApaI, BsmI, and FokI polymorphisms, respectively, compared with the other haplotype groups, thus suggesting that VDR haplotypes modulate the circulating levels of lead in exposed subjects. (orig.)

  3. Evaluation of the Level of ICT Integration in Sciences Subjects at the ...

    African Journals Online (AJOL)

    Evaluation of the Level of ICT Integration in Sciences Subjects at the Namibian College of Open Learning. ... and an observation schedule were used to collect data and then analysed by coding and classifying the data into meaningful themes and categories as per the levels of Rogers's theory of diffusion of innovation.

  4. Short- versus long-term prediction of dementia among subjects with low and high educational levels.

    Science.gov (United States)

    Chary, Emilie; Amieva, Hélène; Pérès, Karine; Orgogozo, Jean-Marc; Dartigues, Jean-François; Jacqmin-Gadda, Hélène

    2013-09-01

    Using simple measures of cognition and disability in a prospective community-living cohort of normal elderly persons, the main objectives of our study were to distinguish short- and long-term predictors for dementia according to educational level and to propose a tool for early detection of subjects at high risk of dementia. Data derived from the French cohort study Paquid (Personnes Agées QUID), which included 3777 subjects, older than 65 years of age, who were followed for a 20-year period. The risk of dementia at 3 years and 10 years was estimated by logistic regression for repeated measures combining data from all the 3- and 10-year windows throughout the follow-up. Predictors included disability assessed by the number of dependent items among four instrumental activities of daily living (IADLs), four neuropsychological tests, five Mini-Mental State Examination (MMSE) subtests, and four items of subjective memory complaints. Of the 2882 included subjects, the number of IADLs remained a predictor of short- and long-term conversion to dementia for those with low educational level (combined with only one cognitive test) whereas the best predictors for more educated subjects combined subjective memory complaints and memory and executive function tests. The episodic memory subtest was the only predictive MMSE subtest. In the high-education-level group, the areas under the receiver-operating characteristic curve of the selected models were 0.85 for 3-year prediction and 0.78 for 10-year prediction. Early predictors of dementia are different according to educational level. Among subjects reaching the secondary school level, early detection of those at high risk of dementia is possible with good predictive performance, with a few simple objective and subjective cognitive evaluations. Copyright © 2013 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

  5. Does E-Reading Enhance Reading Fluency?

    Science.gov (United States)

    Akbar, Rahima S.; Taqi, Hanan A.; Dashti, Abdulmohsin A.; Sadeq, Taiba M.

    2015-01-01

    Extensive reading is reading as much as possible, for one's own pleasure, at a difficulty level at which one can read smoothly and quickly. In the domain of reading, this paper investigates the effect of extensive reading from e-books, through utilizing a number of downloadable reading application programs on the students' e-devices, as opposed to…

  6. Increased prolactin levels are associated with impaired processing speed in subjects with early psychosis.

    Directory of Open Access Journals (Sweden)

    Itziar Montalvo

    Full Text Available Hyperprolactinaemia, a common side effect of some antipsychotic drugs, is also present in drug-naïve psychotic patients and subjects at risk for psychosis. Recent studies in non-psychiatric populations suggest that increased prolactin may have negative effects on cognition. The aim of our study was to explore whether high plasma prolactin levels are associated with poorer cognitive functioning in subjects with early psychoses. We studied 107 participants: 29 healthy subjects and 78 subjects with an early psychosis (55 psychotic disorders with <3 years of illness, 23 high-risk subjects. Cognitive assessment was performed with the MATRICS Cognitive Consensus Cognitive Battery, and prolactin levels were determined as well as total cortisol levels in plasma. Psychopathological status was assessed and the use of psychopharmacological treatments (antipsychotics, antidepressants, benzodiazepines recorded. Prolactin levels were negatively associated with cognitive performance in processing speed, in patients with a psychotic disorder and high-risk subjects. In the latter group, increased prolactin levels were also associated with impaired reasoning and problem solving and poorer general cognition. In a multiple linear regression analysis conducted in both high-risk and psychotic patients, controlling for potential confounders, prolactin and benzodiazepines were independently related to poorer cognitive performance in the speed of processing domain. A mediation analysis showed that both prolactin and benzodiazepine treatment act as mediators of the relationship between risperidone/paliperidone treatment and speed of processing. These results suggest that increased prolactin levels are associated with impaired processing speed in early psychosis. If these results are confirmed in future studies, strategies targeting reduction of prolactin levels may improve cognition in this population.

  7. Pyrethroid insecticide exposure and reproductive hormone levels in healthy Japanese male subjects

    DEFF Research Database (Denmark)

    Yoshinaga, J; Imai, K; Shiraishi, H

    2014-01-01

    )] were explored in 322 male university students in suburban Tokyo. The subjects constituted part of a large cross-sectional survey on the reference value of semen quality of Japanese men. Urinary 3-PBA was detectable in 91% of the subjects demonstrating ubiquitous exposure among the general population...... students who were not aware of their own fertility, whereas the previous study subjects were infertility patients. However, the multiple regression models could explain only a limited fraction of total variance in serum levels of hormones. Identification of other contributors is warranted....

  8. Motivational reading on education, meaningful reading realisation

    Directory of Open Access Journals (Sweden)

    Adriana Qafa

    2017-07-01

    Full Text Available In this study I will present some ideas on today’s educational practice for motivation, the realization of the meaningful reading. There is a special place for the methodical ranking of the reading process, starting in school. Main requests of this reading, consist of the deep meaning of the subject, exploration of the idea, and other elements of the subject, implementation of the technique’s rules of the expressive reading, such as breathing, voice, diction, intonation, spelling, stoppages, logical emphasizes, emotional expressions, temper, timber, gesticulations, and mimic. There is also highlighted the fact that the used method comes from the pupils’ results and depends on the capability and level of the teacher, from the programming’s scale, the tools that are put into disposition, the age and the level of the pupils, and from the environment that the teacher creates during courses. At the end there are some practical guidelines for the realization of the expressive reading in the literature subject.

  9. CBM Reading, Mathematics, and Written Expression at the Secondary Level: Examining Latent Composite Relations Among Indices and Unique Predictions With a State Achievement Test.

    Science.gov (United States)

    Codding, Robin S; Petscher, Yaacov; Truckenmiller, Adrea

    2015-05-01

    A paucity of research has examined the utility of curriculum-based measurement (CBM) for data-based decision making at the secondary level. As schools move to multitiered systems of service delivery, it is conceivable that multiple screening measures will be used that address various academic subject areas. The value of including different CBM indices measures is not well understood. The purpose of this study was to (a) examine the relationship among a variety of reading, writing, and mathematics CBM indices administered to 249 seventh-grade students; (b) investigate amount and patterns of growth; and (c) examine predictive validity to a high-stakes state test using latent factor analysis and multiple indicator growth models. Results indicated strong correspondence among CBM types for fall static scores but weak relationships among slopes. Different patterns of growth were yielded for CBM writing than for CBM reading and mathematics. Findings from this study suggested that although reading, mathematics, and writing CBM were independently and moderately related to both English Language Arts and Math test scores, reading was the strongest predictor when all 3 CBM constructs were considered jointly.

  10. CBM Reading, Mathematics, and Written Expression at the Secondary Level: Examining Latent Composite Relations Among Indices and Unique Predictions With a State Achievement Test

    Science.gov (United States)

    Codding, Robin S.; Petscher, Yaacov; Truckenmiller, Adrea

    2015-01-01

    A paucity of research has examined the utility of curriculum-based measurement (CBM) for data-based decision making at the secondary level. As schools move to multitiered systems of service delivery, it is conceivable that multiple screening measures will be used that address various academic subject areas. The value of including different CBM indices measures is not well understood. The purpose of this study was to (a) examine the relationship among a variety of reading, writing, and mathematics CBM indices administered to 249 seventh-grade students; (b) investigate amount and patterns of growth; and (c) examine predictive validity to a high-stakes state test using latent factor analysis and multiple indicator growth models. Results indicated strong correspondence among CBM types for fall static scores but weak relationships among slopes. Different patterns of growth were yielded for CBM writing than for CBM reading and mathematics. Findings from this study suggested that although reading, mathematics, and writing CBM were independently and moderately related to both English Language Arts and Math test scores, reading was the strongest predictor when all 3 CBM constructs were considered jointly. PMID:26347201

  11. Subjective memory complaints in aging are associated with elevated cortisol levels.

    Science.gov (United States)

    Wolf, Oliver T; Dziobek, Isabel; McHugh, Pauline; Sweat, Victoria; de Leon, Mony J; Javier, Elizabeth; Convit, Antonio

    2005-01-01

    The origin and clinical significance of subjective memory complaints among middle aged and older individuals is not well understood. Associations with objective memory impairments, personality traits or mood disturbances have been reported. Elevated cortisol levels occur in aging and depression and causal links to cognitive or emotional problems have been suggested. The goal of this study was to investigate the associations between basal and feedback indices of cortisol regulation and subjective memory impairment in a sample of healthy middle aged and older subjects (mean age 61.8 years) with (n=27) and without (n=19) subjective memory complaints. Participants with memory complaints had both higher basal cortisol levels and higher cortisol levels after dexamethasone. There was a significant group by gender interaction for basal cortisol levels, where women without memory complaints showed significantly lower cortisol levels, whereas no such difference was found for the men. All effects were not due to slight differences in depression scores. Differences in personality traits or in stress susceptibility might underlie the present findings. Future studies of memory complaints should take a comprehensive approach including relevant endocrine parameters.

  12. The Relations between Lower and Higher Level Comprehension Skills and Their Role in Prediction of Early Reading Comprehension

    Science.gov (United States)

    Silva, Macarena; Cain, Kate

    2015-01-01

    This study of 4- to 6-year-olds had 2 aims: first, to determine how lower level comprehension skills (receptive vocabulary and grammar) and verbal memory support early higher level comprehension skills (inference and literal story comprehension), and second, to establish the predictive power of these skills on subsequent reading comprehension.…

  13. Increased Selenoprotein P Levels in Subjects with Visceral Obesity and Nonalcoholic Fatty Liver Disease

    Directory of Open Access Journals (Sweden)

    Hae Yoon Choi

    2013-02-01

    Full Text Available BackgroundSelenoprotein P (SeP has recently been reported as a novel hepatokine that regulates insulin resistance and systemic energy metabolism in rodents and humans. We explored the associations among SeP, visceral obesity, and nonalcoholic fatty liver disease (NAFLD.MethodsWe examined serum SeP concentrations in subjects with increased visceral fat area (VFA or liver fat accumulation measured with computed tomography. Our study subjects included 120 nondiabetic individuals selected from participants of the Korean Sarcopenic Obesity Study. In addition, we evaluated the relationship between SeP and cardiometabolic risk factors, including homeostasis model of insulin resistance (HOMA-IR, high sensitivity C-reactive protein (hsCRP, adiponectin values, and brachial-ankle pulse wave velocity (baPWV.ResultsSubjects with NAFLD showed increased levels of HOMA-IR, hsCRP, VFA, and several components of metabolic syndrome and decreased levels of adiponectin and high density lipoprotein cholesterol than those of controls. Serum SeP levels were positively correlated with VFA, hsCRP, and baPWV and negatively correlated with the liver attenuation index. Not only subjects with visceral obesity but also those with NAFLD exhibited significantly increased SeP levels (P<0.001. In multiple logistic regression analysis, the subjects in the highest SeP tertile showed a higher risk for NAFLD than those in the lowest SeP tertile, even after adjusting for potential confounding factors (odds ratio, 7.48; 95% confidence interval, 1.72 to 32.60; P=0.007.ConclusionCirculating SeP levels were increased in subjects with NAFLD as well as in those with visceral obesity and may be a novel biomarker for NAFLD.

  14. Subject-level differences in reported locations of cutaneous tactile and nociceptive stimuli

    Directory of Open Access Journals (Sweden)

    Peter eSteenbergen

    2012-11-01

    Full Text Available Recent theoretical advances on the topic of body representations have raised the question whether spatial perception of touch and nociception involve the same representations. Various authors have established that subjective localizations of touch and nociception are displaced in a systematic manner. The relation between veridical stimulus locations and localizations can be described in the form of a perceptual map; these maps differ between subjects. Recently, evidence was found for a common set of body representations to underlie spatial perception of touch and slow and fast pain, which receive information from modality specific primary representations. There are neurophysiological clues that the various cutaneous senses may not share the same primary representation. If this is the case, then differences in primary representations between touch and nociception may cause subject-dependent differences in perceptual maps of these modalities. We studied localization of tactile and nociceptive sensations on the forearm using electrocutaneous stimulation. The perceptual maps of these modalities differed at the group level. When assessed for individual subjects, the differences localization varied in nature between subjects. The agreement of perceptual maps of the two modalities was moderate. These findings are consistent with a common internal body representation underlying spatial perception of touch and nociception. The subject level differences suggest that in addition to these representations other aspects, possibly differences in primary representation and/or the influence of stimulus parameters, lead to differences in perceptual maps in individuals.

  15. Comparative analysis of performance in reading and writing of children exposed and not exposed to high sound pressure levels.

    Science.gov (United States)

    Santos, Juliana Feitosa dos; Souza, Ana Paula Ramos de; Seligman, Lilian

    2013-01-01

    To analyze the possible relationships between high sound pressure levels in the classroom and performance in the use of lexical and phonological routes in reading and writing. This consisted on a quantitative and exploratory study. The following measures were carried out: acoustic measurement, using the dosimeter, visual inspection of the external auditory canal, tonal audiometry thresholds, speech recognition tests and acoustic immittance; instrument for evaluation of reading and writing of isolated words. The non-parametric χ² test and Fisher's exact test were used for data analysis. The results of acoustic measurements in 4 schools in Santa Maria divided the sample of 87 children of third and fourth years of primary school, aged 8 to 10 years, in 2 groups. The 1st group was exposed to sound levels higher than 80 dB(A) (Study group) and the 2nd group at levels lower than 80 dB(A) (Control group). Higher prevalence of correct answers in reading and writing of nonwords, reading irregular words and frequency effect were observed. Predominance of correct answers in the writing of irregular words was observed in the Control group. For the Study group, a higher number of type errors neologism in reading and writing were observed, especially regarding the writing of nonwords and the extension effect; fewer errors of lexicalization type and verbal paragraphy in writing were observed. In assessing the reading and writing skills, children in the Study group exposed to high noise levels had poorer performance in the use of lexical and phonological routes, both in reading and in writing.

  16. Beyond reading level: a systematic review of the suitability of cancer education print and Web-based materials.

    Science.gov (United States)

    Finnie, Ramona K C; Felder, Tisha M; Linder, Suzanne Kneuper; Mullen, Patricia Dolan

    2010-12-01

    Consideration of categories related to reading comprehension--beyond reading level--is imperative to reach low literacy populations effectively. "Suitability" has been proposed as a term to encompass six categories of such factors: content, literacy demand graphics, layout/typography, learning stimulation, and cultural appropriateness. Our purpose was to describe instruments used to evaluate categories of suitability in cancer education materials in published reports and their findings. We searched databases and reference lists for evaluations of print and Web-based cancer education materials to identify and describe measures of these categories. Studies had to evaluate reading level and at least one category of suitability. Eleven studies met our criteria. Seven studies reported inter-rater reliability. Cultural appropriateness was most often assessed; four instruments assessed only surface aspects of cultural appropriateness. Only two of seven instruments used, the suitability assessment of materials (SAM) and the comprehensibility assessment of materials (SAM + CAM), were described as having any evidence of validity. Studies using Simplified Measure of Goobledygook (SMOG) and Fry reported higher average reading level scores than those using Flesh-Kincaid. Most materials failed criteria for reading level and cultural appropriateness. We recommend more emphasis on the categories of suitability for those developing cancer education materials and more study of these categories and reliability and validity testing of instruments.

  17. The Impact of Intensive Reading Intervention on Level of Attention in Middle School Students.

    Science.gov (United States)

    Roberts, Greg; Rane, Shruti; Fall, Anna-Mária; Denton, Carolyn A; Fletcher, Jack M; Vaughn, Sharon

    2015-01-01

    The purpose of the study was to estimate the impact of reading intervention on ratings of student attention over time. We used extant data from a longitudinal randomized study of a response-based reading intervention to fit a multiple-indicator, multilevel growth model. The sample at randomization was 54% male, 18% limited English proficient, 85% eligible for free or reduced-price lunch, 58% African American, and 32% Hispanic. Reading ability was measured by using the Woodcock-Johnson III Tests of Achievement. Attention was measured by using the Strengths and Weaknesses of ADHD Symptoms and Normal Behavior Scale. Findings indicate that intensive, response-based reading intervention over 3 years improved reading achievement and behavioral attention in middle school struggling readers, with treatment directly affecting reading, which in turn influenced attention. In the business-as-usual condition, there was no relation between improved reading and attention. The results are consistent with a correlated liabilities model of comorbidity. The results do not align with the inattention-as-cause hypothesis, which predicts that reading intervention should not affect attention. The findings do not support, but do not necessarily preclude, the phenocopy hypothesis. The results are especially pertinent for older students who may be inattentive partly because of years of struggling with reading.

  18. Fluency and reading comprehension in students with reading difficulties.

    Science.gov (United States)

    Nascimento, Tânia Augusto; Carvalho, Carolina Alves Ferreira de; Kida, Adriana de Souza Batista; Avila, Clara Regina Brandão de

    2011-12-01

    To characterize the performance of students with reading difficulties in decoding and reading comprehension tasks as well as to investigate the possible correlations between them. Sixty students (29 girls) from 3rd to 5th grades of public Elementary Schools were evaluated. Thirty students (Research Group - RG), ten from each grade, were nominated by their teachers as presenting evidences of learning disabilities. The other thirty students were indicated as good readers, and were matched by gender, age and grade to the RG, composing the Comparison Group (CG). All subjects were assessed regarding the parameters of reading fluency (rate and accuracy in words, pseudowords and text reading) and reading comprehension (reading level, number and type of ideas identified, and correct responses on multiple choice questions). The RG presented significantly lower scores than the CG in fluency and reading comprehension. Different patterns of positive and negative correlations, from weak to excellent, among the decoding and comprehension parameters were found in both groups. In the RG, low values of reading rate and accuracy were observed, which were correlated to low scores in comprehension and improvement in decoding, but not in comprehension, with grade increase. In CG, correlation was found between different fluency parameters, but none of them was correlated to the reading comprehension variables. Students with reading and writing difficulties show lower values of reading fluency and comprehension than good readers. Fluency and comprehension are correlated in the group with difficulties, showing that deficits in decoding influence reading comprehension, which does not improve with age increase.

  19. Subject oriented and problem based text materials as an object of a flexible foreign language reading in research projects

    OpenAIRE

    SEROVA TAMARA S.; PIPCHENKO ELENA L.

    2015-01-01

    The article introduces the academic research work of students within competence based approach, the models of academic problem based research projects taken up as means to develop flexible foreign language reading skills; reveals selection principles and corpus didactic design of text materials in a form of a macrotext, hypertext, and video course.

  20. Serum hormonal levels in HIV/AIDS infected male subjects on ...

    African Journals Online (AJOL)

    This study was designed to assess the serum hormonal levels (Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), Testosterone, Estrogen, Progesterone, Prolactin and Cortisol) in symptomatic HIV/AIDS male subjects on ART. A total of 411 participants aged between 17 and 58 (43 ±10) years were randomly ...

  1. Levels of plasma fibrinogen and D-dimer in subjects with subclinical hyperthyroidism.

    Science.gov (United States)

    Coban, Erkan; Aydemir, Mustafa

    2008-01-01

    During the last 15 years, several risk markers for atherosclerosis, such as fibrinogen and D-dimer, have been identified. The role of elevated fibrinogen levels as an independent risk factor for coronary, cerebral, and peripheral vascular disease is well established on the basis of clinical and epidemiological studies. Increased D-dimer levels are associated with increased risk of future myocardial infarction, stroke, and peripheral vascular disease. The aim of this study was to evaluate the alterations in fibrinogen and D-dimer, which indicates overall thrombotic activity, in subjects with subclinical hyperthyroidism. Thirty-six subclinical hyperthyroidic subjects and 36 euthyroidic control subjects matched for age, gender, and body mass index were selected. The levels of plasma fibrinogen and D-dimer in all subjects were measured. The level of fibrinogen was significantly higher in the subclinical hyperthyroidic group than in the euthyroidic group (296.9+/-74.3 mg/dl vs. 255.0+/-41.7 mg/dl, psubclinical hyperthyroidic group than in the euthyroidic group (261.9+/-47.8 mg/dl vs. 216.4+/-32.1 mg/dl, psubclinical hyperthyroidism present a relatively hypercoagulable state. This state could contribute to increased thromboembolic risk in subclinical hyperthyroidism.

  2. High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects.

    Science.gov (United States)

    Korsten, M A; Matsuzaki, S; Feinman, L; Lieber, C S

    1975-02-20

    Blood actaldehyde and ethanol levels were measured in 11 subjects, six with chronic alcholoism and five nonalcholic controls, after alcohol had been given intravenously. Despite a progressive fall in blood ethanol over a range of 54 to 33 mM/acetaldehyde did not decrease in any of the 11 subjects. The mean acetaldehyde plateau level was significantly (p less than 0.001) higher in alcoholic (42.7 plus or minus 1.2 mum) than in nonalcoholic (26.5 plus or minus 1.5 mum) subjects. When the mean blood ethanol concentration reached 24 mM,the acetaldehyde plateau ended abruptly in each subject. The ethanol concentration at which this fall of blood acetaldehyde occurred suggests desaturation of an ethanol oxidizing system other than alcohol dehydrogenase and indicates that at high ethanol blood levels, such a system contributes to ethanol oxidation. The highet acetaldehyde levels in alcholism may result from both greater activity of this system and mitochondrial damage, and could contribut to the neurologic, hepatic and cardiac complications of alcoholism.

  3. Perceptions of Classroom Assessment Tasks: An Interplay of Gender, Subject Area, and Grade Level

    Science.gov (United States)

    Alkharusi, Hussain Ali; Al-Hosni, Salim

    2015-01-01

    This study investigates students' perceptions of classroom assessment tasks as a function of gender, subject area, and grade level. Data from 2753 students on Dorman and Knightley's (2006) Perceptions of Assessment Tasks Inventory (PATI) were analyzed in a MANOVA design. Results showed that students tended to hold positive perceptions of their…

  4. Decreased levels of stem cell factor in subjects with incident coronary events.

    Science.gov (United States)

    Wigren, M; Rattik, S; Hultman, K; Björkbacka, H; Nordin-Fredrikson, G; Bengtsson, E; Hedblad, B; Siegbahn, A; Gonçalves, I; Nilsson, J

    2016-02-01

    It has been proposed that vascular progenitor cells play an important role in vascular repair, but their possible clinical importance in cardiovascular disease has not been fully characterized. Vascular endothelial growth factor A, placental growth factor and stem cell factor (SCF) are three growth factors that are important in recruiting vascular progenitor cells. In this study, we investigated the association between the plasma levels of these growth factors and incident coronary events (CEs). Levels of the three growth factors were measured using the proximity extension assay technique in baseline plasma samples from 384 subjects with a first CE (mean follow-up 14.0 ± 4.3 years) and 409 event-free control subjects matched by sex and age, as well as in homogenates from 201 endarterectomy specimens. After controlling for known cardiovascular disease risk factors in a Cox regression model, subjects in the lowest SCF tertile had a hazard ratio of 1.70 (95% confidence interval 1.14-2.54) compared with subjects in the highest SCF tertile. Lower SCF levels were also associated with more severe carotid disease, less fibrous atherosclerotic plaques and an increased incidence of heart failure. Expression of the SCF receptor c-kit was demonstrated in the subendothelial layer and fibrous cap of human atherosclerotic plaques. Smokers and subjects with diabetes had decreased levels of SCF compared with control subjects. To our knowledge, this is the first clinical study to provide evidence to support a key role for SCF and progenitor cells in vascular repair. We suggest that the SCF-c-kit pathway may be a promising biomarker and therapeutic target in cardiovascular disease. © 2015 The Association for the Publication of the Journal of Internal Medicine.

  5. Uric acid levels in subjects with bipolar disorder: A comparative meta-analysis.

    Science.gov (United States)

    Bartoli, Francesco; Crocamo, Cristina; Mazza, Mario Gennaro; Clerici, Massimo; Carrà, Giuseppe

    2016-10-01

    Previous research has hypothesised increased uric acid levels, possibly because of an amplified purinergic metabolism and a reduced adenosine activity, in subjects with bipolar disorder. This systematic review and meta-analysis aimed at estimating if individuals with bipolar disorder had uric acid levels higher than both healthy controls and subjects with major depression (trait marker hypothesis). It also tested if uric acid levels could differ in different phases of bipolar disorder (state marker hypothesis). Meta-analyses were carried out generating pooled standardized mean differences (SMDs), using random-effects models. Heterogeneity between studies was estimated using the I(2) index. Relevant sensitivity and meta-regression analyses were conducted. We searched main Electronic Databases, identifying twelve studies that met our inclusion criteria. Meta-analyses showed increased uric acid levels in individuals with bipolar disorder as compared with both healthy controls (SMD = 0.65, p uric acid levels were higher in manic/mixed phases as compared with depressive ones (SMD = 0.34; p = 0.04, I(2) = 58.8%), a sensitivity analysis did not confirm the association. In sum, our meta-analysis shows that subjects with bipolar disorder have uric acid levels higher than healthy controls. The potential role of factors that might clarify the nature of this association deserves additional research. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims.

    Science.gov (United States)

    Rafalo-Ulinska, Anna; Piotrowska, Joanna; Kryczyk, Agata; Opoka, Włodzimierz; Sowa-Kucma, Magdalena; Misztak, Paulina; Rajkowska, Grazyna; Stockmeier, Craig A; Datka, Wojciech; Nowak, Gabriel; Szewczyk, Bernadeta

    2016-12-01

    Major depressive disorder (MDD) is a serious psychiatric illness, associated with an increasing rate of suicide. The pathogenesis of depression may be associated with the disruption of zinc (Zn) homeostasis. In the brain, several proteins that regulate Zn homeostasis are present, including Zn transporters (ZnTs) which remove Zn from the cytosol. The present study was designed to investigate whether depression and suicide are associated with alterations in the expression of the ZnTs protein. Protein levels of ZnT1, ZnT3, ZnT4, ZnT5 and ZnT6 were measured in postmortem brain tissue from two different cohorts. Cohort A contained 10 subjects diagnosed with MDD (7 were suicide victims) and 10 psychiatrically-normal control subjects and cohort B contained 11 non-diagnosed suicide victims and 8 sudden-death control subjects. Moreover, in cohort A we measured protein level of NMDA (GluN2A subunit), AMPA (GluA1 subunit) and 5-HT1A receptors and PSD-95. Proteins were measured in the prefrontal cortex (PFC) using Western blotting. In addition, Zn concentration was measured using a voltammetric method. There was a significant increase in protein levels of ZnT1, ZnT4, ZnT5 in the PFC in MDD, relative to control subjects, while ZnT3 protein level was decreased in MDD. There was no significant difference in the Zn concentration in the PFC between control and MDD subjects. Similarly, in the PFC of suicide victims (non-diagnosed), an increase in protein levels of ZnT1, ZnT4, ZnT5 and ZnT6 was observed. Conversely, protein levels of ZnT3 were decreased in both suicide victims and subjects with MDD, in comparison with control subjects. There was also a significant decrease in the protein level of GluA1, GluN2A, PSD-95 and 5-HT1A in MDD. Our studies suggest that alterations in Zn transport proteins are associated with the pathophysiology of MDD and suicide. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Comparison of Different Levels of Reading Comprehension between Hearing-Impaired Loss and Normal-Hearing Students

    Directory of Open Access Journals (Sweden)

    Azam Sharifi

    2011-12-01

    Full Text Available Background and Aim: Reading skill is one of the most important necessities of students' learning in everyday life. This skill is referred to the ability of comprehension, comment and conclusion from texts and receiving the meaning of the massage which is composed. Educational development in any student has a direct relation with the ability of the comprehension. This study is designed to investigate the effects of hearing loss on reading comprehension in hearing-impaired students compared to normal-hearing ones.Methods: Seventeen hearing-impaired students in 4th year of primary exceptional schools in Karaj, Robatkarim and Shahriyar, Iran, were enrolled in this cross-sectional study. Seventeen normal-hearing students were randomly selected from ordinary schools next to exceptional ones as control group. They were compared for different levels of reading comprehension using the international standard booklet (PIRLS 2001. Results: There was a significant difference in performance between hearing-impaired and normal- hearing students in different levels of reading comprehension (p<0.05.Conclusion: Hearing loss has negative effects on different levels of reading comprehension, so in exceptional centers, reconsideration in educational planning in order to direct education from memorizing to comprehension and deeper layers of learning seems necessary.

  8. Effect of external classroom noise on schoolchildren's reading and mathematics performance: correlation of noise levels and gender.

    Science.gov (United States)

    Papanikolaou, M; Skenteris, N; Piperakis, S M

    2015-02-01

    The present study investigated the effect of low, medium, and high traffic road noise as well as irrelevant background speech noise on primary school children's reading and mathematical performance. A total of 676 participants (324 boys, 47.9% and 352 girls, 52.1%) of the 4th and 5th elementary classes participated in the project. The participants were enrolled in public primary schools from urban areas and had ages ranging from 9 to 10 years and from. Schools were selected on the basis of increasing levels of exposure to road traffic noise and then classified into three categories (Low noise: 55-66 dB, Medium noise: 67-77 dB, and High noise: 72-80 dB). We measured reading comprehension and mathematical skills in accordance with the national guidelines for elementary education, using a test designed specifically for the purpose of this study. On the one hand, children in low-level noise schools showed statistically significant differences from children in medium- and high-level noise schools in reading performance (pschools differed significantly from children in high-level noise schools but only in mathematics performance (p=0.001). Girls in general did better in reading score than boys, especially in schools with medium- and high-level noise. Finally the levels of noise and gender were found to be two independent factors.

  9. Endotoxin levels correlate positively with a sedentary lifestyle and negatively with highly trained subjects

    Directory of Open Access Journals (Sweden)

    Oyama Lila M

    2010-08-01

    Full Text Available Abstract Introduction A sedentary lifestyle increases the risk of developing cardiovascular disease, obesity, and diabetes. This phenomenon is supported by recent studies suggesting a chronic, low-grade inflammation status. Endotoxin derived from gut flora may be key to the development of inflammation by stimulating the secretion of inflammatory factors. This study aimed to examine plasma inflammatory markers and endotoxin levels in individuals with a sedentary lifestyle and/or in highly trained subjects at rest. Methods: Fourteen male subjects (sedentary lifestyle n = 7; highly trained subjects n = 7 were recruited. Blood samples were collected after an overnight fast (~12 h. The plasmatic endotoxin, plasminogen activator inhibitor type-1 (PAI-1, monocyte chemotactic protein-1 (MCP1, ICAM/CD54, VCAM/CD106 and lipid profile levels were determined. Results Endotoxinemia was lower in the highly trained subject group relative to the sedentary subjects (p Conclusion These results indicate that a lifestyle associated with high-intensity and high-volume exercise induces favorable changes in chronic low-grade inflammation markers and may reduce the risk for diseases such as obesity, diabetes and cardiovascular diseases.

  10. Single-subject research design: recommendations for levels of evidence and quality rating.

    Science.gov (United States)

    Romeiser Logan, Lynne; Hickman, Robbin R; Harris, Susan R; Heriza, Carolyn B

    2008-02-01

    The aim of this article is to present a set of evidence levels, accompanied by 14 quality or rigor questions, to foster a critical review of published single-subject research articles. In developing these guidelines, we reviewed levels of evidence and quality/rigor criteria that are in wide use for group research designs, e.g. randomized controlled trials, such as those developed by the Treatment Outcomes Committee of the American Academy for Cerebral Palsy and Developmental Medicine. We also reviewed methodological articles on how to conduct and critically evaluate single-subject research designs (SSRDs). We then subjected the quality questions to interrater agreement testing and refined them until acceptable agreement was reached. We recommend that these guidelines be implemented by clinical researchers who plan to conduct single-subject research or who incorporate SSRD studies into systematic reviews, and by clinicians who aim to practise evidence-based medicine and who wish to critically review pediatric single-subject research.

  11. Why Some Students Are Less Motivated in Reading Classes at Tertiary Level in Bangladesh

    Science.gov (United States)

    Ullah, Md. Mohib; Fatema, Sayeda

    2013-01-01

    The universal importance of reading, a receptive skill, is enormous. It encompasses a major part of learning and teaching a language. Reading ameliorates language competence of learners and it has an all-inclusive effect on their acquisition of second language. But some students are not found appropriately motivated or found demotivated in reading…

  12. Reading Images in Graphic Novels: Taking Students to a "Greater Thinking Level"

    Science.gov (United States)

    Pantaleo, Sylvia

    2014-01-01

    During a classroom-based study that explored the teaching and learning of visual elements of art and design, Grade 7 students had the opportunity to read four graphic novels. Theoretically, the research was informed by social semiotics, visual literacy, sociocultural theory, and Rosenblatt's transactional theory of reading. The instructional unit…

  13. Color Your Classroom IV: A Reading Guide on the Secondary Level.

    Science.gov (United States)

    Mississippi Materials & Resource Center, Gulfport.

    This curriculum guide, designed for use with secondary migrant students, contains activities in the reading areas of structural analysis, literal comprehension, inferential comprehension, vocabulary, and reading in the content areas. Within these four broad areas, activities are presented in the following specific skill areas: (1) hearing…

  14. Teachers' and Students' Perceptions of Gender-Differentiated Reading Instruction at the High School Level

    Science.gov (United States)

    Taylor, Luke N., III

    2014-01-01

    In a rural Alabama school district, 38.46% of the students failed the reading portion of the high school graduation examination. While the teachers in the school district were trained to differentiate instruction according to ability and gender, the impact of gender-differentiated reading instruction was unknown. The purpose of this case study was…

  15. Glycoalkaloid and calystegine levels in table potato cultivars subjected to wounding, light, and heat treatments.

    Science.gov (United States)

    Petersson, Erik V; Arif, Usman; Schulzova, Vera; Krtková, Veronika; Hajšlová, Jana; Meijer, Johan; Andersson, Hans Christer; Jonsson, Lisbeth; Sitbon, Folke

    2013-06-19

    Potato tubers naturally contain a number of defense substances, some of which are of major concern for food safety. Among these substances are the glycoalkaloids and calystegines. We have here analyzed levels of glycoalkaloids (α-chaconine and α-solanine) and calystegines (A₃, B₂, and B₄) in potato tubers subjected to mechanical wounding, light exposure, or elevated temperature: stress treatments that are known or anticipated to induce glycoalkaloid levels. Basal glycoalkaloid levels in tubers varied between potato cultivars. Wounding and light exposure, but not heat, increased tuber glycoalkaloid levels, and the relative response differed among the cultivars. Also, calystegine levels varied between cultivars, with calystegine B4 showing the most marked variation. However, the total calystegine level was not affected by wounding or light exposure. The results demonstrate a strong variation among potato cultivars with regard to postharvest glycoalkaloid increases, and they suggest that the biosynthesis of glycoalkaloids and calystegines occurs independently of each other.

  16. Relationship between salivary cortisol levels and regional cerebral glucose metabolism in nondemented elderly subjects

    Energy Technology Data Exchange (ETDEWEB)

    Kwak, Young Bin; Cho, Sang Soo; Lee, Sung Ha; Chey, Jean Yung; Kim, Sang Eun [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2004-07-01

    Cortisol is a primary stress hormone for flight-or-fight response in human. Increased levels of cortisol have been associated with memory and learning impairments. However, little is known about the role of cortisol on brain/cognitive functions in older adults. We compared regional cerebral glucose metabolism between elderly subjects with high and low cortisol levels using FDG PET. Salivary cortisol levels were measured four times during a day, and an average of the four measurements was used as the standard cortisol level for the analyses. From a population of 120 nondemented elderly subjects, 19 (mean age, 70.1{+-}4.9 y: 2 males and 17 females) were identified as the high (> mean + 1 SD of the total population) cortisol subjects (mean cortisol, 0.69{+-}0.09 {mu} g/dL), while 14 (mean age, 67.2{+-}4.5 y: all females) as the low (< mean 1 SD) cortisol (mean cortisol, 0.27{+-}0.03 {mu} g/dL). A voxel-wise comparison of FDG PET images from the high and low cortisol subjects was performed using SPM99. When compared with the low cortisol group, the high cortisol group had significant hypometabolism in the right middle temporal gyrus, left precuneus, right parahippocampal gyrus, right inferior temporal and superior temporal gyri (P < 0.01 uncorrected, k = 100). There was no significant increase of glucose metabolism in the high cortisol group compared with the low cortisol group (P < 0.01 uncorrected, k = 100). The high cortisol elderly subjects had hypometabolism in the parahippocampal and temporal gyri and precuneus, regions involved in memory and other cognitive functions. This may represent the preclinical metabolic correlates of forthcoming cognitive dysfunction associated with stress in the elderly. Longitudinal studies of brain metabolism and cognitive function are warranted.

  17. Effects of a Whole-Class Reading Program Designed for Different Reading Levels and the Learning Needs of L1 and L2 Children

    Science.gov (United States)

    Seifert, Susanne; Schwab, Susanne; Gasteiger-Klicpera, Barbara

    2016-01-01

    This article aims to evaluate the whole-class reading program Language And Reading Skills (LARS) and its effects on the decoding, reading comprehension, and language abilities of 1st-language (L1) and 2nd-language (L2) German 2nd graders. The program consisted of teacher training and differentiated reading materials adapted to the needs of both L1…

  18. The Use of a Computer-Based Reading Rate Development Program on Pre-University Intermediate Level ESL Learners' Reading Speeds

    Science.gov (United States)

    Haupt, John

    2015-01-01

    Improving L2 learners reading fluency has been identified by leading L2 reading researchers as an important aspect of L2 reading instruction (Grabe, 2004, 2009; Nation, 2009). A number of studies have been conducted on the use of paper-based fluency development methods on ESL and EFL students reading speeds and showed positive results (Al-Homoud…

  19. The Unique Relation of Silent Reading Fluency to End-of-Year Reading Comprehension: Understanding Individual Differences at the Student, Classroom, School, and District Levels

    Science.gov (United States)

    Kim, Young-Suk; Petscher, Yaacov; Foorman, Barbara

    2015-01-01

    Despite many previous studies on reading fluency (measured by a maze task) as a screening measure, our understanding is limited about the utility of silent reading fluency in predicting later reading comprehension and contextual influences (e.g., schools and districts) on reading comprehension achievement. In the present study we examined: (1) How…

  20. Long-term endurance training increases serum cathepsin S levels in healthy female subjects.

    Science.gov (United States)

    Sponder, M; Minichsdorfer, C; Campean, I-A; Emich, M; Fritzer-Szekeres, M; Litschauer, B; Strametz-Juranek, J

    2017-11-27

    Circulating cathepsin S (CS) has been associated with a lower risk for breast cancer in a large Swedish cohort. Long-term physical activity has been shown to have beneficial effects on the development of various cancer subtypes, in particular breast and colorectal cancers. The aim of this study was to investigate the effect of long-term endurance sport on CS levels in females. Thirty-six of 40 subjects completed the study. Subjects were told to increase their activity pensum for 8 months reaching 150 min/week moderate or 75 min/week intense exercise. Ergometries were performed at the beginning and the end of the study to prove/quantify the performance gain. Blood samples were drawn at baseline and every 2 months. Serum CS levels were measured by ELISA. To analyse the change and the progression of CS, Wilcoxon rank sum and Friedman tests were used. The sportive group (performance gain by > 4.9%) showed a significant increase of CS levels from 3.32/2.73/4.09 to 4.00/3.09/5.04 ng/ml (p = 0.008) corresponding to an increase of 20.5%. We could show a significant increase of circulating CS levels in healthy female subjects induced by long-term physical activity. CS, occurring in the tumour microenvironment, is well-known to promote tumour growth, e.g. by ameliorating angiogenesis. However, the role of circulating CS in cancer growth is not clear. As physical activity is known as preventive intervention, in particular concerning breast and colorectal cancers, and long-term physical activity leads to an increase of CS levels in female subjects, circulating CS might even be involved in this protective effect. Clinical trial registration: NCT02097199.

  1. Tooth element levels indicating exposure profiles in diabetic and hypertensive subjects from Mysore, India.

    Science.gov (United States)

    Nagaraj, G; Sukumar, A; Nandlal, B; Vellaichamy, S; Thanasekaran, K; Ramanathan, A L

    2009-12-01

    Element contents of teeth elucidate exposure nature, but less is known about association of tooth element concentrations of diabetics and hypertensives with exposure profile. Present study aims to estimate copper, chromium, iron, zinc, nickel, and lead concentrations in the permanent teeth of control, diabetic, and hypertensive subjects from Mysore. The results show that lead levels of teeth (Pb-T) are higher in the hypertensives and diabetics, whereas copper levels of teeth (Cu-T) are lower in the hypertensives and users of stainless steel utensils than that of controls and users of mixed utensils. The elevated Cu-T levels found in the users of mixed utensils that being made of several metals are ascribed to leaching effect of sour and spicy food of Indian cuisine. The element levels were influenced by diet (Zn-T), place of living, sex and income (Pb-T) of the subjects, but not by age, drinking water from different sources, and certain habits viz., smoking, alcohol consumption, chewing betel, and nut. Thus, it is evident that high Pb-T and low Cu-T levels may be related with diabetes and hypertension and high Pb-T and Cu-T levels, respectively, in the urbanites, and the users of mixed utensils may show different exposure profiles from environment and utensils.

  2. Comparison of Antioxidant Status and Vitamin D Levels between Multiple Sclerosis Patients and Healthy Matched Subjects

    Directory of Open Access Journals (Sweden)

    Ehsan Hejazi

    2014-01-01

    Full Text Available Objective. The aim of the present study was to compare the serum levels of total antioxidant status (TAS and 25(OH D3 and dietary intake of multiple sclerosis (MS patients with those of normal subjects. Method. Thirty-seven MS patients (31 women and the same number of healthy matched controls were compared for their serum levels and dietary intake of 25(OH D3 and TAS. Sun exposure and the intake of antioxidants and vitamin D rich foods were estimated through face-to-face interview and food frequency questionnaire. Results. Dietary intake of antioxidants and vitamin D rich foods, vitamin C, vitamin A, and folate was not significantly different between the two groups. There were also no significant differences in the mean levels of 25(OH D3 and TAS between the study groups. Both groups had low serum levels of 25(OH D3 and total antioxidants. Conclusion. No significant differences were detected in serum levels and dietary intake of vitamin D and antioxidants between MS patients and healthy controls. All subjects had low antioxidant status and vitamin D levels.

  3. Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects.

    Science.gov (United States)

    Banni, Sebastiano; Carta, Gianfranca; Murru, Elisabetta; Cordeddu, Lina; Giordano, Elena; Sirigu, Anna Rita; Berge, Kjetil; Vik, Hogne; Maki, Kevin C; Di Marzo, Vincenzo; Griinari, Mikko

    2011-01-30

    We have previously shown that krill oil (KO), more efficiently than fish oil, was able to downregulate the endocannabinoid system in different tissues of obese zucker rats.We therefore aimed at investigating whether an intake of 2 g/d of either KO or menhaden oil (MO), which provides 309 mg/d of EPA/DHA 2:1 and 390 mg/d of EPA/DHA 1:1 respectively, or olive oil (OO) for four weeks, is able to modify plasma endocannabinoids in overweight and obese subjects.The results confirmed data in the literature describing increased levels of endocannabinoids in overweight and obese with respect to normo-weight subjects. KO, but not MO or OO, was able to significantly decrease 2-arachidonoylglycerol (2-AG), although only in obese subjects. In addition, the decrease of 2-AG was correlated to the plasma n-6/n-3 phospholipid long chain polyunsaturated fatty acid (LCPUFA) ratio. These data show for the first time in humans that relatively low doses of LCPUFA n-3 as KO can significantly decrease plasma 2-AG levels in obese subjects in relation to decrease of plasma phospholipid n-6/n-3 LCPUFA ratio. This effect is not linked to changes of metabolic syndrome parameters but is most likely due to a decrease of 2-AG biosynthesis caused by the replacement of 2-AG ultimate precursor, arachidonic acid, with n-3 PUFAs, as previously described in obese Zucker rats.

  4. Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects

    Directory of Open Access Journals (Sweden)

    Giordano Elena

    2011-01-01

    Full Text Available Abstract We have previously shown that krill oil (KO, more efficiently than fish oil, was able to downregulate the endocannabinoid system in different tissues of obese zucker rats. We therefore aimed at investigating whether an intake of 2 g/d of either KO or menhaden oil (MO, which provides 309 mg/d of EPA/DHA 2:1 and 390 mg/d of EPA/DHA 1:1 respectively, or olive oil (OO for four weeks, is able to modify plasma endocannabinoids in overweight and obese subjects. The results confirmed data in the literature describing increased levels of endocannabinoids in overweight and obese with respect to normo-weight subjects. KO, but not MO or OO, was able to significantly decrease 2-arachidonoylglycerol (2-AG, although only in obese subjects. In addition, the decrease of 2-AG was correlated to the plasma n-6/n-3 phospholipid long chain polyunsaturated fatty acid (LCPUFA ratio. These data show for the first time in humans that relatively low doses of LCPUFA n-3 as KO can significantly decrease plasma 2-AG levels in obese subjects in relation to decrease of plasma phospholipid n-6/n-3 LCPUFA ratio. This effect is not linked to changes of metabolic syndrome parameters but is most likely due to a decrease of 2-AG biosynthesis caused by the replacement of 2-AG ultimate precursor, arachidonic acid, with n-3 PUFAs, as previously described in obese Zucker rats.

  5. Investigation of Plasma Conjugated Linoleic Acid Levels in Obese and Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Hümeyra Yerlikaya

    2012-04-01

    Full Text Available Aim: Obesity is very widespread health problem especially in developed countries. It occurs due to more body fat accumulation than normal levels, it implicates with many factors in the etiology and it needs to treatment. Conjugated linoleic acid (CLA refers to a class of positional and geometric conjugated isomers of the omega-6 essential fatty acid, linoleic acid. An array of purposed beneficial effects of CLA, such as capability of reducing or eliminating cancer, preventing heart disease and improving immune function on human healthy have been reported. This study has aimed to investigate biologically active isomers of CLA (10-trans, 12-cis CLA and 9-cis,11-trans CLA in obese and healthy subjects. Material and Method: The study was performed on 105 obese people (22M, 83F aged 18-70 years and 80 control subjects (20M,60F aged 18-70 years. Body mass index of the obese subjects was more than 35 kg/m2 and that of healthy controls was less than 25 kg/m2. Plasma 10-trans, 12-cis CLA (t10,c12 CLA and 9-cis,11-trans CLA (c9,t11 CLA levels were measured by GS-MS technique. Results: t10,c12 and c9,t11 isomers of CLA levels of the obese subjects were found as follows: 13.423.94 and 9.23 5.61 mg/L respectively. The same parameters of the controls were as follows: 13.153.67 and 9.80 5.06 mg/L respectively. Discussion: The differences between plasma CLA isomers levels of obese and control subjects were not significant. But, isomers of CLA negatively correlated with waist-to-hip ratio, which accepted as a good indicator of body fat distribution, in obese subjects. These findings suggest that the levels of t10,c12 CLA and c9,t11 CLA isomers inversely associated with body fat mass in obesity.

  6. Metacognitive Reading Strategies in Learning Disability: Relations between Usage Level, Academic Self-Efficacy and Self-Concept

    Science.gov (United States)

    Girli, Alev; Öztürk, Halil

    2017-01-01

    The purpose of this study is to investigate the relationship between the usage levels of metacognitive reading strategies by students diagnosed with specific learning disability (SLD), academic self-efficacy and the concept of self, in comparison to their typically developing (TD) peers. The data to be used in the study were collected using the…

  7. State-of-the-Art Article: The Role and Importance of Lower-Level Processes in Second Language Reading

    Science.gov (United States)

    Nassaji, Hossein

    2014-01-01

    This article examines current research on the role and importance of lower-level processes in second language (L2) reading. The focus is on word recognition and its subcomponent processes, including various phonological and orthographic processes. Issues related to syntactic and semantic processes and their relationship with word recognition are…

  8. Fifth-Grade Turkish Elementary School Students' Listening and Reading Comprehension Levels with Regard to Text Types

    Science.gov (United States)

    Yildirim, Kasim; Yildiz, Mustafa; Ates, Seyit; Rasinski, Timothy

    2010-01-01

    The aim of this study was to examine fifth grade elementary school students' listening and reading comprehension levels with regard to text types. This study was conducted on 180 fifth grade elementary school students in Sincan-Ankara in the spring semester of the academic year 2008-2009. The comprehension test was administered to students. The…

  9. Dimensions of Discourse Level Oral Language Skills and Their Relation to Reading Comprehension and Written Composition: An Exploratory Study

    Science.gov (United States)

    Kim, Young-Suk Grace; Park, Cheahyung; Park, Younghee

    2015-01-01

    We examined the relations of discourse-level oral language skills [i.e., listening comprehension, and oral retell and production of narrative texts (oral retell and production hereafter)] to reading comprehension and written composition. Korean-speaking first grade students (N = 97) were assessed on listening comprehension, oral retell and…

  10. Examining the Relationship between Course Length and Academic Performance in College-Level Psychology with an Investigation into Reading Proficiency

    Science.gov (United States)

    Valenti, Elizabeth C.

    2013-01-01

    College dropout is a complex problem resulting in an array of negative repercussions for students, universities, and society. The study explored the impact of reading proficiency on academic success in a college-level introductory psychology course offered in both traditional and accelerated formats. A quantitative, quasi-experimental design was…

  11. An Event-Level Examination of Sex Differences and Subjective Intoxication in Alcohol-Related Aggression

    OpenAIRE

    Quinn, Patrick D.; Stappenbeck, Cynthia A.; Fromme, Kim

    2013-01-01

    Laboratory-based experimental research has demonstrated that the pharmacological effects of alcohol can increase aggressive responding. Given mixed findings and concerns regarding task validity, however, it remains uncertain whether this effect holds constant across men and women and whether variability in subjective alcohol intoxication contributes to alcohol-related aggression. In the present investigation, we used four years of event-level data in a sample of 1,775 college students (140,61...

  12. The Structure of the Subjective Economic Well-being Depending on Its Level

    Directory of Open Access Journals (Sweden)

    V A Hashchenko

    2008-06-01

    Full Text Available The article contains the new approach to studying the psychology of the economic well-being, i.e. structural-level. From its position the subjective economic well-being is revealed as polyphenomenological formation, the contents and specificity of which are defined by the natural organization of the system of its structural formations. The new data are submitted, allowing to establish and explain a number of features and laws of the organization of SEW.

  13. Sedentary subjects have higher PAI-1 and lipoproteins levels than highly trained athletes

    Directory of Open Access Journals (Sweden)

    Lira Fabio S

    2010-01-01

    Full Text Available Abstract Physical exercise protects against the development of cardiovascular disease, partly by lowering plasmatic total cholesterol, LDL-cholesterol and increased HDL-cholesterol levels. In addition, it is now established that reduction plasmatic adiponectin and increased C-reactive protein (CRP and plasminogen activator inhibitor-1 (PAI-1 levels play a role in the maintenance of an inflammatory state and in the development of cardiovascular disease. This study aimed to examine plasma lipid profile and inflammatory markers levels in individual with sedentary lifestyle and/or highly trained athletes at rest. Methods: Fourteen male subjects (sedentary lifestyle n = 7 and highly trained athletes n = 7 were recruited. Blood samples were collected after an overnight fast (~12 h. The plasmatic lipid profile (Triglycerides, HDL-cholesterol, LDL-cholesterol, total cholesterol, LDL-oxidized and total cholesterol/HDL-c ratio, glucose, adiponectin, C - reactive protein and PAI-1 levels were determined. Results: Total cholesterol, LDL-cholesterol, TG and PAI-1 levels were lower in highly trained athletes group in relation to sedentary subjects (p

  14. Predicting Levels of Reading and Writing Achievement in Typically Developing, English-Speaking 2nd and 5th Graders

    Science.gov (United States)

    Jones, Jasmin Niedo; Abbott, Robert D.; Berninger, Virginia W.

    2014-01-01

    Human traits tend to fall along normal distributions. The aim of this research was to evaluate an evidence-based conceptual framework for predicting expected individual differences in reading and writing achievement outcomes for typically developing readers and writers in early and middle childhood from Verbal Reasoning with or without Working Memory Components (phonological, orthographic, and morphological word storage and processing units, phonological and orthographic loops, and rapid switching attention for cross-code integration). Verbal Reasoning (reconceptualized as Bidirectional Cognitive-Linguistic Translation) plus the Working Memory Components (reconceptualized as a language learning system) accounted for more variance than Verbal Reasoning alone, except for handwriting for which Working Memory Components alone were better predictors. Which predictors explained unique variance varied within and across reading (oral real word and pseudoword accuracy and rate, reading comprehension) and writing (handwriting, spelling, composing) skills and grade levels (second and fifth) in this longitudinal study. Educational applications are illustrated and theoretical and practical significance discussed. PMID:24948868

  15. Definition of a focus of reading and writing teaching in the process from preparatory to primary level at school

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    Rudy Doria Correa

    2014-08-01

    Full Text Available This paper shows the results of a research exercise in order to define an approach of reading and writing’s teaching and learning in the process from preparatory to primary education in Asodesi’s school in the city of Monteria - Córdoba. This experience is a part of the investigation “classroom projects: an experience of action research in language teaching at school”, theoretically oriented from the study of various approaches about teaching reading and writing early, with a qualitative methodology (IA, by forming a study group work (SGW, within which teachers reflect on their teaching practices, in order to improve and transform them. The main results are: the definition of a comprehensive approach of teaching reading and writing, linked to the goals of training offered in classroom projects in primary and secondary levels and the development of skills incomprehension and textual production. 

  16. Predicting Levels of Reading and Writing Achievement in Typically Developing, English-Speaking 2nd and 5th Graders.

    Science.gov (United States)

    Jones, Jasmin Niedo; Abbott, Robert D; Berninger, Virginia W

    2014-05-01

    Human traits tend to fall along normal distributions. The aim of this research was to evaluate an evidence-based conceptual framework for predicting expected individual differences in reading and writing achievement outcomes for typically developing readers and writers in early and middle childhood from Verbal Reasoning with or without Working Memory Components (phonological, orthographic, and morphological word storage and processing units, phonological and orthographic loops, and rapid switching attention for cross-code integration). Verbal Reasoning (reconceptualized as Bidirectional Cognitive-Linguistic Translation) plus the Working Memory Components (reconceptualized as a language learning system) accounted for more variance than Verbal Reasoning alone, except for handwriting for which Working Memory Components alone were better predictors. Which predictors explained unique variance varied within and across reading (oral real word and pseudoword accuracy and rate, reading comprehension) and writing (handwriting, spelling, composing) skills and grade levels (second and fifth) in this longitudinal study. Educational applications are illustrated and theoretical and practical significance discussed.

  17. How Much Will the Sea Level Rise? Outcome Selection and Subjective Probability in Climate Change Predictions.

    Science.gov (United States)

    Juanchich, Marie; Sirota, Miroslav

    2017-08-17

    We tested whether people focus on extreme outcomes to predict climate change and assessed the gap between the frequency of the predicted outcome and its perceived probability while controlling for climate change beliefs. We also tested 2 cost-effective interventions to reduce the preference for extreme outcomes and the frequency-probability gap by manipulating the probabilistic format: numerical or dual-verbal-numerical. In 4 experiments, participants read a scenario featuring a distribution of sea level rises, selected a sea rise to complete a prediction (e.g., "It is 'unlikely' that the sea level will rise . . . inches") and judged the likelihood of this sea rise occurring. Results showed that people have a preference for predicting extreme climate change outcomes in verbal predictions (59% in Experiments 1-4) and that this preference was not predicted by climate change beliefs. Results also showed an important gap between the predicted outcome frequency and participants' perception of the probability that it would occur. The dual-format reduced the preference for extreme outcomes for low and medium probability predictions but not for high ones, and none of the formats consistently reduced the frequency-probability gap. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  18. The relations between lower and higher level comprehension skills and their role in prediction of early reading comprehension

    OpenAIRE

    Silva, Macarena; Cain, Kate

    2015-01-01

    This study of 4- to 6-year-olds had two aims. First to determine how lower-level comprehension skills (receptive vocabulary and grammar) and verbal memory support early higher-level comprehension skills (inference and literal story comprehension). Second to establish the predictive power of these skills on subsequent reading comprehension. Eighty-two children completed assessments of nonverbal ability, receptive vocabulary and grammar, verbal short-term memory, and inferential and literal com...

  19. Effect of Low-Level Laser Stimulation on EEG Power in Normal Subjects with Closed Eyes

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    Jih-Huah Wu

    2013-01-01

    Full Text Available In a previous study, we found that the low-level laser (LLL stimulation at the palm with a frequency of 10 Hz was able to induce significant brain activation in normal subjects with opened eyes. However, the electroencephalography (EEG changes to LLL stimulation in subjects with closed eyes have not been studied. In the present study, the laser array stimulator was applied to deliver insensible laser stimulations to the palm of the tested subjects with closed eyes (the laser group. The EEG activities before, during, and after the laser stimulation were collected. The EEG amplitude powers of each EEG frequency band at 19 locations were calculated. These power data were then analyzed by SPSS software using repeated-measure ANOVAs and appropriate posthoc tests. We found a pronounced decrease in the EEG power in alpha-bandwidth during laser simulation and then less decrease in the EEG power in delta-bandwidth in normal subjects with laser stimulation. The EEG power in beta-bandwidth in the right occipital area also decreased significantly in the laser group. We suggest that LLL stimulation might be conducive to falling into sleep in patients with sleep problems.

  20. Caries-free subjects have high levels of urease and arginine deiminase activity

    Directory of Open Access Journals (Sweden)

    Evelyn REYES

    2014-06-01

    Full Text Available Objectives: This study investigated the relationship between urease and arginine deiminase system (ADS activities and dental caries through a cross-sectional study. Material and Methods: Urease and ADS activities were measured in saliva and plaque samples from 10 caries-free subjects and 13 caries-active. Urease activity was obtained from the ammonia produced by incubation of plaque and saliva samples in urea. ADS activity was obtained from the ammonia generated by the arginine-HCl and Tris-maleate buffer. Specific activity was defined as micromoles of ammonia per minute per milligram of protein. Shapiro-Wilk statistical test was used to analyze the distribution of the data, and Mann-Whitney test was used to determine the significance of the data. Results: The specific urease activity in saliva and plaque was significantly higher in individuals with low DMFT scores. ADS activity in saliva (6.050 vs 1.350, p=0.0154 and plaque (8.830 vs 1.210, p=0.025 was also higher in individuals with low DMFT scores. Conclusions: Caries-free subjects had a higher ammonia generation activity by urease and arginine deiminase system for both saliva and plaque samples than low caries-active subjects. High levels of alkali production in oral environment were related to caries-free subjects.

  1. Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects.

    Science.gov (United States)

    Hsia, Chien-Hsun; Shen, Ming-Ching; Lin, Jen-Shiou; Wen, Yao-Ke; Hwang, Kai-Lin; Cham, Thau-Ming; Yang, Nae-Cherng

    2009-03-01

    Nattokinase, a serine proteinase from Bacillus subtilis, is considered to be one of the most active functional ingredients found in natto. In this study, we hypothesized that nattokinase could reduce certain factors of blood clotting and lipids that are associated with an increase risk for cardiovascular disease (CVD). Thus, an open-label, self-controlled clinical trial was conducted on subjects of the following groups: healthy volunteers (Healthy Group), patients with cardiovascular risk factors (Cardiovascular Group), and patients undergoing dialysis (Dialysis Group). All subjects ingested 2 capsules of nattokinase (2000 fibrinolysis units per capsule) daily orally for 2 months. The laboratory measurements were performed on the screening visit and, subsequently, regularly after the initiation of the study. The intent-to-treat analysis was performed on all 45 enrolled subjects. By use of mixed model analysis, a significant time effect, but not group effect, was observed in the change from baseline of fibrinogen (P = .003), factor VII (P nattokinase. No significant changes of uric acid or notable adverse events were observed in any of the subjects. In summary, this study showed that oral administration of nattokinase could be considered as a CVD nutraceutical by decreasing plasma levels of fibrinogen, factor VII, and factor VIII.

  2. Plasma nociceptin/orphanin FQ levels in response to the hyperventilation test in healthy subjects.

    Science.gov (United States)

    Fontana, Fiorella; Pizzi, Carmine; Bernardi, Pasquale; Pich, Emilio Merlo; Bedini, Andrea; Spampinato, Santi

    2010-04-01

    In vitro and in vivo studies demonstrated that nociceptin/orphanin FQ inhibits norepinephrine release, while the effects of norepinephrine on nociceptin/orphanin FQ release remain unknown. Previous studies in healthy and hypertensive subjects showed that prolonged and forced hyperventilation induces different blood pressure (BP) responses depending on changes in plasma catecholamine levels. We investigated whether the effects of hyperventilation on the sympatho-adrenergic system involve nociceptin/orphanin FQ release. Fifty-six healthy subjects (26 females, mean age 63+/-2 and 30 males, mean age 63+/-3) underwent the hyperventilation test. A hierarchical cluster analysis based on BP response to hyperventilation identified three groups of subjects: group 1 (n=20) with a decrease in BP, norepinephrine (1311.1+/-45.5 fmol/ml versus 900.0+/-55.3 fmol/ml, Phyperventilation in groups 1 and 3 were directly (Phyperventilation changes plasma nociceptin/orphanin FQ levels due to the direct effects of hypocapnic alkalosis or to different sympatho-adrenergic system responses. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  3. System of Indicators of the Level of Costs of Financing an Economic Subject

    Directory of Open Access Journals (Sweden)

    Laktionova Aleksandra A.

    2013-11-01

    Full Text Available The article offers a system of indicators of the level of costs of financing economic subjects, in the basis of which there is a function of formation of recommendations or identification of directions and priorities in the part of selection of one or another source of financing, its urgency and specific features of attraction of resources, on the basis of information on the level of agent’s costs, information asymmetry costs, financial instability, transaction and market indicators of cost of financial resources. The article pays a special attention to a significant structure forming factor of the ownership structure, which identifies the volume and logic of interconnection of all costs of financing and determining incentives and risks in the system of management of financial activity of an economic subject from the point of view of all participants. It exerts especially big influence upon formation of such implicit costs of financing as agent’s costs and information asymmetry costs. The system of factors of stimulants and de-stimulants of costs of financing includes factors of external environment (macro-economic and market indicators of cost and institutional provision and internal environment (ownership structure, characteristic of investment activity and financing an economic subject, organisation of business and corporate management.

  4. Measuring the degradation level of polymer films subjected to partial discharges

    Energy Technology Data Exchange (ETDEWEB)

    Bozzo, R.; Gemme, C.; Guastavino, F. [Univ. of Genoa (Italy). Electrical Engineering Dept.; Tiemblo, P. [Inst. de Ciencia y Tecnologia de Polimeros, Madrid (Spain)

    1996-12-31

    Polymer films have been subjected to partial discharge (PD) aging. It is shown that statistical quantities derived from partial discharges patterns can be related to test conditions, film characteristics and degradation level. PDs have been measured by means of a digital system. Several resulting PD patterns have been elaborated and about 50 derived and statistical quantities have been obtained for each pattern. The effects of the test conditions on the derived quantities has been studied with relevance to the following items: To recognize the kind of film under test; to correlate the value of quantities with the degradation level of the film (i.e., to focus at the quantities which change with time); to find a link between the quantities values and the test ambient conditions (i.e., relative humidity); to determine the influence of the film thickness; and to evidence the effect of the voltage level.

  5. Vinegar intake reduces body weight, body fat mass, and serum triglyceride levels in obese Japanese subjects.

    Science.gov (United States)

    Kondo, Tomoo; Kishi, Mikiya; Fushimi, Takashi; Ugajin, Shinobu; Kaga, Takayuki

    2009-08-01

    Acetic acid (AcOH), a main component of vinegar, recently was found to suppress body fat accumulation in animal studies. Hence we investigated the effects of vinegar intake on the reduction of body fat mass in obese Japanese in a double-blind trial. The subjects were randomly assigned to three groups of similar body weight, body mass index (BMI), and waist circumference. During the 12-week treatment period, the subjects in each group ingested 500 ml daily of a beverage containing either 15 ml of vinegar (750 mg AcOH), 30 ml of vinegar (1,500 mg AcOH), or 0 ml of vinegar (0 mg AcOH, placebo). Body weight, BMI, visceral fat area, waist circumference, and serum triglyceride levels were significantly lower in both vinegar intake groups than in the placebo group. In conclusion, daily intake of vinegar might be useful in the prevention of metabolic syndrome by reducing obesity.

  6. The reliability of side to side measurements of upper extremity activity levels in healthy subjects

    Directory of Open Access Journals (Sweden)

    Amasay Tal

    2010-07-01

    Full Text Available Abstract Background In both clinical and occupational settings, ambulatory sensors are becoming common for assessing all day measurements of arm motion. In order for the motion of a healthy, contralateral side to be used as a control for the involved side, the inherent side to side differences in arm usage must be minimal. The goal of the present study was to determine the reliability of side to side measurements of upper extremity activity levels in healthy subjects. Methods Thirty two subjects with no upper extremity pathologies were studied. Each subject wore a triaxial accelerometer on both arms for three and a half hours. Motion was assessed using parameters previously reported in the literature. Side to side differences were compared with the intraclass correlation coefficient, standard error of the mean, minimal detectable change scores and a projected sample size analysis. Results The variables were ranked based on their percentage of minimal detectable change scores and sample sizes needed for paired t-tests. The order of these rankings was found to be identical and the top ranked parameters were activity counts per hour (MDC% = 9.5, n = 5, jerk time (MDC% = 15.8, n = 8 and percent time above 30 degrees (MDC% = 34.7, n = 9. Conclusions In general, the mean activity levels during daily activities were very similar between dominant and non-dominant arms. Specifically, activity counts per hour, jerk time, and percent time above 30 degrees were found to be the variables most likely to reveal significant difference or changes in both individuals and groups of subjects. The use of ambulatory measurements of upper extremity activity has very broad uses for occupational assessments, musculoskeletal injuries of the shoulder, elbow, wrist and hand as well as neurological pathologies.

  7. Comics as a Literary-Didactic Method and Their Use for Reducing Gender Differences in Reading Literacy at the Primary Level of Education

    Directory of Open Access Journals (Sweden)

    Maja Kerneža

    2016-06-01

    Full Text Available The aim of the present study was to examine the effect of the systematic use of comics as a literary-didactic method to reduce gender differences in reading literacy and reading motivation at the primary level of education. It was assumed that the use of comics would have a positive effect on pupils’ reading literacy and reading motivation, while also reducing the aforementioned differences between boys and girls. The dimensions of reading literacy and reading motivation were examined in experimental and control groups, before and after the intervention, by means of questionnaires and tests for pupils. The sample consisted of 143 pupils from second to fifth grade from two Slovenian primary schools in a rural environment, of which 73 pupils participated in the experimental group and 70 pupils represented the control group. Effects of the use of comics as a literary-didactic method were not found: using comics as a literary-didactic method did not have a statistically significant effect on pupils’ reading literacy and reading motivation. However, when the four-way structure of the research (taking into account the age and gender of the pupils was considered, some subgroups showed a statistically significant increase in reading interest and attitude towards reading. No reduction of gender differences in reading literacy and reading motivation was found. Based on the results, guidelines for further research are established and suggestions are offered for teachers’ work.

  8. Substance Dependency's Effect on Reading Decoding and Comprehension: Reading Decoding and Comprehension Levels as Indicators of Brain Dysfunctioning with Ramifications for Traditional Rehabilitation Programming.

    Science.gov (United States)

    Schadler, Debbie E.

    This paper discusses the outcomes of a study that investigated the effects of substance dependency on the reading decoding and comprehension of 497 adolescents (ages 12-18) involved in an inpatient drug and alcohol rehabilitation program. The first part of the study involved the formal assessment of reading decoding and reading comprehension…

  9. An event-level examination of sex differences and subjective intoxication in alcohol-related aggression.

    Science.gov (United States)

    Quinn, Patrick D; Stappenbeck, Cynthia A; Fromme, Kim

    2013-04-01

    Laboratory-based experimental research has demonstrated that the pharmacological effects of alcohol can increase aggressive responding. Given mixed findings and concerns regarding task validity, however, it remains uncertain whether this effect holds constant across men and women and whether variability in subjective alcohol intoxication contributes to alcohol-related aggression. In this investigation, the authors used 4 years of event-level data in a sample of 1,775 college students (140,618 total observations) to provide a test of laboratory-derived findings on the link between alcohol and aggression in an alternative methodology. They found support for several such findings: (a) Within-person increases in alcohol intoxication, as assessed by estimated blood alcohol concentrations (eBACs), were associated with increases in the probability of aggression at the drinking-episode level; (b) this association was significantly stronger among men than among women; and (c) within-person variability and between-persons individual differences in levels of subjective alcohol intoxication were associated with aggression over and beyond eBACs. Cross-methodological replication can reduce the impact of constraints specific to experimental studies on conclusions regarding alcohol's relation with aggression.

  10. LEVELING CHARACTERISTICS INTERCONNECTION BETWEEN PERSONALITY COMPETITIVENESS AND SUBJECTIVE WELL-BEING OF HIGH SCHOOL STUDENTS

    Directory of Open Access Journals (Sweden)

    E E Bocharova

    2016-12-01

    Full Text Available The paper presents the theoretical and empirical study of the relationship of personality characteristics of level of competitiveness and subjective well-being. The study was performed on a sample of high school students ( N = 70, female and male; 16-17 years old, differing in the level of personal competitiveness, with psycho-diagnostic tools, “Express-diagnostics of personal competitiveness”(G.M. Manuilov, “Express-diagnostics of the level of social frustration (L. Wasserman”, “The scale of subjective well-being” (M.V. Sokolova, “My self-regulation of behavior and activity” (V.I. Morosanova. It is shown that the ability for self-education, self-improvement, self-planning and modeling their prospects, achieving the goal on the background of their satisfaction with relations with the immediate environment acts as a basic capacity for personality competition in adolescents. The applied aspect of the research problem can be implemented in the development of programs of psycho- pedagogical support of the formation and development of personal competitiveness of students.

  11. An Event-Level Examination of Sex Differences and Subjective Intoxication in Alcohol-Related Aggression

    Science.gov (United States)

    Quinn, Patrick D.; Stappenbeck, Cynthia A.; Fromme, Kim

    2013-01-01

    Laboratory-based experimental research has demonstrated that the pharmacological effects of alcohol can increase aggressive responding. Given mixed findings and concerns regarding task validity, however, it remains uncertain whether this effect holds constant across men and women and whether variability in subjective alcohol intoxication contributes to alcohol-related aggression. In the present investigation, we used four years of event-level data in a sample of 1,775 college students (140,618 total observations) to provide a test of laboratory-derived findings on the link between alcohol and aggression in an alternative methodology. We found support for several such findings: 1) Within-person increases in alcohol intoxication, as assessed by estimated blood alcohol concentrations (eBACs), were associated with increases in the probability of aggression at the drinking-episode level; 2) This association was significantly stronger among men than among women; and 3) Within-person variability and between-persons individual differences in levels of subjective alcohol intoxication were associated with aggression over and beyond eBACs. Cross-methodological replication can reduce the impact of constraints specific to experimental studies on conclusions regarding alcohol’s relation with aggression. PMID:23421356

  12. Fetuin-A serum levels are not correlated to kidney function in long-lived subjects.

    Science.gov (United States)

    Bellia, Chiara; Tomaiuolo, Rossella; Caruso, Antonietta; Sasso, Bruna Lo; Zarrilli, Federica; Carru, Ciriaco; Deiana, Maria; Zinellu, Angelo; Pinna, Sara; Castaldo, Giuseppe; Deiana, Luca; Ciaccio, Marcello

    2012-06-01

    Serum Fetuin A has been identified as an inhibitor of ectopic calcification. It is reduced in subjects with chronic kidney disease (CKD) and it has been proposed as a potential link between CKD and the higher prevalence of arterial calcification observed in these patients. During aging both the stiffening of arterial wall due to calcification and a decline in kidney function are frequent. The aim of the study is to investigate if Fetuin A serum levels are associated with aging and with AHSG T256S polymorphism. Moreover, we aim at investigate whether serum Fetuin A is correlated to kidney function in this setting of senescence. 256 health long-lived subjects (age 92 [81-100]) were recruited for the study. Serum Fetuin A was evaluated by ELISA, Cystatin C by immune-nephelometry. AHSG T256S was determinated by PCR-RFLP. Serum Fetuin A shows a significant correlation with age (r=0.20; P=0.0048). AHSG TS and SS genotypes are associated to lower levels of serum protein (0.27 [0.19-0.29] g/L vs 0.42 [0.32-0.49] g/L; PAHSG polymorphism have lower levels of the circulating protein. No correlation with kidney function decline was observed. Other mechanisms should be investigated to explain the increase of Fetuin A with age. Copyright © 2012 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  13. Serving the army as secretaries: intersectionality, multi-level contract and subjective experience of citizenship.

    Science.gov (United States)

    Lomsky-Feder, Edna; Sasson-Levy, Orna

    2015-03-01

    With the growing elusiveness of the state apparatus in late modernity, military service is one of the last institutions to be clearly identified with the state, its ideologies and its policies. Therefore, negotiations between the military and its recruits produce acting subjects of citizenship with long-lasting consequences. Arguing that these negotiations are regulated by multi-level (civic, group, and individual) contracts, we explore the various meanings that these contracts obtain at the intersectionality of gender, class, and ethnicity; and examine how they shape the subjective experience of soldierhood and citizenship. More particularly, we analyse the meaning of military service in the retrospective life stories of Israeli Jewish women from various ethno-class backgrounds who served as army secretaries - a low-status, feminine gender-typed occupation within a hyper-masculine organization. Findings reveal that for women of the lower class, the organizing cultural schema of the multi-level contract is that of achieving respectability through military service, which means being included in the national collective. Conversely, for middle-class women, it is the sense of entitlement that shapes their contract with the military, which they expect to signify and maintain their privileged status. Thus, while for the lower class, the multi-level contract is about inclusion within the boundaries of the national collective, for the dominant groups, this contract is about reproducing social class hierarchies within national boundaries. © London School of Economics and Political Science 2014.

  14. Reading for Pleasure: A Reading Resource Room.

    Science.gov (United States)

    Battles, Jane; Tambuscio, Colleen

    1991-01-01

    A reading resource room was developed for 59 deaf and hard-of-hearing secondary-level students, to improve vocabulary and reading skills and encourage reading for pleasure. Books of interest to teenagers with limited reading levels were located from several publishing companies and were arranged in a space with shelves and comfortable seating.…

  15. Brain and Behavioral Assessment of Executive Functions for Self-Regulating Levels of Language in Reading Brain.

    Science.gov (United States)

    Berninger, Virginia W; Richards, Todd L; Abbott, Robert D

    2017-11-01

    This brief research report examines brain-behavioral relationships specific to levels of language in the complex reading brain. The first specific aim was to examine prior findings for significant fMRI connectivity from four seeds (left precuneus, left occipital temporal, left supramarginal, left inferior frontal) for each of four levels of language-subword, word (word-specific spelling or affixed words), syntax (with and without homonym foils or affix foils), and multi-sentence text to identify significant fMRI connectivity (a) unique to the lower level of language when compared to the immediately higher adjacent level of language across subword-word, word-syntax, and syntax-text comparisons; and (b) involving a brain region associated with executive functions. The second specific aim was to correlate the magnitude of that connectivity with standard scores on tests of Focused Attention (D-K EFS Color Word Form Inhibition) and Switching Attention (Wolf & Denckla Rapid Automatic Switching). Seven correlations were significant. Focused Attention was significantly correlated with the word level (word-specific spellings of real words) fMRI task in left cingulum from left inferior frontal seed. Switching Attention was significantly correlated with the (a) subword level (grapheme-phoneme correspondence) fMRI task in left and right Cerebellum V from left supramarginal seed; (b) the word level (word-specific spelling) fMRI task in right Cerebellum V from left precuneus seed; (c) the syntax level (with and without homonym foils) fMRI task in right Cerebellum V from left precuneus seed and from left supramarginal seed; and (d) syntax level (with and without affix foils) fMRI task in right Cerebellum V from left precuneus seed. Results are discussed in reference to neuropsychological assessment of supervisory attention (focused and switching) for specific levels of language related to reading acquisition in students with and without language-related specific learning

  16. Psilocybin links binocular rivalry switch rate to attention and subjective arousal levels in humans.

    Science.gov (United States)

    Carter, Olivia L; Hasler, Felix; Pettigrew, John D; Wallis, Guy M; Liu, Guang B; Vollenweider, Franz X

    2007-12-01

    Binocular rivalry occurs when different images are simultaneously presented to each eye. During continual viewing of this stimulus, the observer will experience repeated switches between visual awareness of the two images. Previous studies have suggested that a slow rate of perceptual switching may be associated with clinical and drug-induced psychosis. The objective of the study was to explore the proposed relationship between binocular rivalry switch rate and subjective changes in psychological state associated with 5-HT2A receptor activation. This study used psilocybin, the hallucinogen found naturally in Psilocybe mushrooms that had previously been found to induce psychosis-like symptoms via the 5-HT2A receptor. The effects of psilocybin (215 microg/kg) were considered alone and after pretreatment with the selective 5-HT2A antagonist ketanserin (50 mg) in ten healthy human subjects. Psilocybin significantly reduced the rate of binocular rivalry switching and increased the proportion of transitional/mixed percept experience. Pretreatment with ketanserin blocked the majority of psilocybin's "positive" psychosis-like hallucinogenic symptoms. However, ketanserin had no influence on either the psilocybin-induced slowing of binocular rivalry or the drug's "negative-type symptoms" associated with reduced arousal and vigilance. Together, these findings link changes in binocular rivalry switching rate to subjective levels of arousal and attention. In addition, it suggests that psilocybin's effect on binocular rivalry is unlikely to be mediated by the 5-HT2A receptor.

  17. Evaluation of Salivary Leptin Levels in Healthy Subjects and Patients with Advanced Periodontitis

    Directory of Open Access Journals (Sweden)

    Afshin Khorsand

    2016-08-01

    Full Text Available Objectives: Leptin is a hormone-like protein produced by the adipose tissue. It plays an important role in protection of host against inflammation and infection. Some studies have reported changes in leptin levels in the gingival crevicular fluid (GCF, saliva and blood serum of patients with periodontal disease compared to healthy individuals. The aim of the present study was to compare the salivary leptin levels in patients with advanced periodontitis and healthy individuals.Materials and Methods: In this case-control study, the salivary samples of healthy individuals and patients with advanced periodontitis with clinical attachment loss >5mm were obtained using a standardized method and the leptin levels were measured in the salivary samples by means of ELISA. The effects of the periodontal status and sex on the salivary leptin levels of both groups were statistically analyzed by two-way ANOVA.Results: The means ± standard deviation (SD of salivary leptin levels in healthy subjects and patients with advanced periodontitis were 34.27±6.88 and 17.87±5.89 pg/mL, respectively. Statistical analysis showed that the effect of sex on the salivary leptin levels was not significant (P=0.91, while the effect of advanced periodontitis on the salivary leptin levels was significant compared to healthy individuals (P<0.0001.Conclusions: In patients with advanced periodontitis, the salivary leptin levels were significantly lower compared to healthy individuals. Thus, assessment of salivary leptin can be done as a non-invasive and simple method to determine the susceptibility of patients to advanced periodontitis.

  18. Spelling and Reading Development: The Effect of Teaching Children Multiple Levels of Representation in Their Orthography

    Science.gov (United States)

    Devonshire, Victoria; Morris, Paul; Fluck, Michael

    2013-01-01

    A novel intervention was developed to teach reading and spelling literacy to 5 to 7 year-old students using explicit instruction of morphology, etymology, phonology, and form rules. We examined the effects of the intervention compared to a phonics-based condition using a cross-over design with a baseline measure. One hundred and twenty children…

  19. Mira y lee: Libro de lectura 1, nivel 1 (Look and Read: Reader 1, Level 1).

    Science.gov (United States)

    Martinez, Emiliano; And Others

    This reading textbook contains a series of stories designed to relate to the natural interest of the school child. Students learn about a Puerto Rican family living in New York. New vocabulary is introduced gradually for the student to memorize. Included are exercises in oral expression and comprehension, auditory discrimination, intonation,…

  20. Polychlorinated biphenyl serum levels in subjects with hepatocellular carcinoma as compared with the general population

    Directory of Open Access Journals (Sweden)

    Claudia Zani

    2014-11-01

    Full Text Available Background. Polychlorinated biphenyls (PCBs have been recognized as human carcinogens and cause liver cancer in animal experimental studies. However, no study investigated their association with hepatocellular carcinoma (HCC so far.  This study aimed to evaluate the serum PCB concentration in HCC patients and in healthy subjects of the general population living in Brescia, North Italy, a highly industrialized area with heavy PCB environmental pollution due to the presence of a PCB producing factory. Methods. Lipid-adjusted PCB concentrations, computed as the sum of 24 congeners, were measured in the serum of 101 HCC patients and in 101 healthy subjects of the same age and gender.Results. Hepatitis B and C virus infection and history of heavy alcohol intake were found, alone and combined, in 87% of HCC patients. No difference was found in PCB serum concentration of HCC patients with and without, and according to, the major risk factors for liver disease. No significant difference was observed in serum total PCB concentration between HCC patients (median: 1081; range: 287.0-3182.0 ng/g lipid and healthy subjects (median: 1199.3; range: 225.7-22825 ng/g lipid. PCB congeners 118, 138, 153, 156, 180 and 194 were the only ones found over the detection limit in at least 30% of HCC patients. The serum level of PCB 118, but not that of other congeners, was higher in HCC patients than in healthy subjects.Conclusion. These findings  do not support the hypothesis that PCBs play an important role in HCC development, although a contribution by some specific congeners cannot be ruled out. 

  1. The level of job satisfaction and its relation to midwives' subjective quality of life

    Directory of Open Access Journals (Sweden)

    Beata Babiarczyk

    2014-02-01

    Full Text Available Background: According to the so called Transactional Model of Quality of Life, job satisfaction is a part of subjective well-being. The aim of this study was to explore the relationships between professional commitment, expressed as job satisfaction or dissatisfaction, consideration of leaving the profession or/and workplace, and subjective assessment of well-being among midwives working at hospitals. Materials and Methods: The study was a part of the international research project, coordinated by the University of Ostrava. The group of respondents consisted of 176 midwives working at selected hospitals in the Silesian region. The study was conducted using the method of diagnostic survey, questionnaire techniques and standardized research tools, such as McCloskey/Mueller Satisfaction Scale (MMSS, Personal Wellbeing Index-Adult (PWI-A and Subjective Emotional Habitual Wellbeing Scale (SEHP. Results: The overall midwives' job satisfaction was found to be at a medium level. Respondents less satisfied with various aspects of work (interaction, co-workers, professional opportunities, praise/recognition, control/responsibility and life (standard of living and achievements in life were significantly more often considering changing their jobs. Dissatisfaction with the extrinsic rewards (salary, vacation, benefits package had additionally influenced the frequency of considering changing the profession. The respondents were characterized by much lower sense of present and future security than that observed in Western countries, as well as by low satisfaction with standard of living and feeling part of the society. Conclusions: Job satisfaction and subjective well-being remain in strong relationship, and although it is difficult to determine the direction of these relationships, they seem to have a significant impact on each other. Med Pr 2014;65(1:99–108

  2. Insulin resistance is accompanied by increased von Willebrand factor levels in nondiabetic women: a study of offspring of type 2 diabetic subjects compared to offspring of nondiabetic subjects

    DEFF Research Database (Denmark)

    Foss, Anne-Catherine; Vestbo, Else; Frøland, Anders

    2002-01-01

    : We compared vWF, fibrinogen and fibronectin in 88 nondiabetic offspring of type 2 diabetic subjects (relatives) and 103 offspring of nondiabetic subjects (controls). Other measurements included urinary albumin excretion rate, blood pressure, lipid profile and insulin resistance using homeostasis......OBJECTIVES: To examine whether levels of von Willebrand factor (vWF), fibrinogen and fibronectin are related to a parental history of type 2 diabetes and to determine possible explanatory factors for high versus low vWF and fibrinogen. DESIGN: Cross-sectional study. SUBJECTS, MAIN OUTCOME MEASURES...

  3. Investigating statistical differences in connectivity patterns properties at single subject level: a new resampling approach.

    Science.gov (United States)

    Toppi, J; Anzolin, A; Petti, M; Cincotti, F; Mattia, D; Salinari, S; Babiloni, F; Astolfi, L

    2014-01-01

    Methods based on the multivariate autoregressive (MVAR) approach are commonly used for effective connectivity estimation as they allow to include all available sources into a unique model. To ensure high levels of accuracy for high model dimensions, all the observations are used to provide a unique estimation of the model, and thus of the network and its properties. The unavailability of a distribution of connectivity values for a single experimental condition prevents to perform statistical comparisons between different conditions at a single subject level. This is a major limitation, especially when dealing with the heterogeneity of clinical conditions presented by patients. In the present paper we proposed a novel approach to the construction of a distribution of connectivity in a single subject case. The proposed approach is based on small perturbations of the networks properties and allows to assess significant changes in brain connectivity indexes derived from graph theory. Its feasibility and applicability were investigated by means of a simulation study and an application to real EEG data.

  4. Fasting plasma glucose levels and coronary artery calcification in subjects with impaired fasting glucose.

    Science.gov (United States)

    Eun, Young-Mi; Kang, Sung-Goo; Song, Sang-Wook

    2016-01-01

    Prediabetes is associated with an increased risk of cardiovascular disease (CVD). While the association of impaired glucose tolerance with CVD has been shown in many studies, the relationship between impaired fasting glucose (IFG) and CVD remains unclear. The purpose of this study was to compare the coronary artery calcium (CAC) scores of participants with normal fasting glucose versus those with IFG, according to fasting plasma glucose (FPG) levels, and to assess whether differences in CAC scores were independent of important confounders. Retrospective study. Health Promotion Center of the University Hospital (Gyeonggi-do, South Korea), during the period 2010-2014. Participants were enrolled from the general population who visited for a medical check-up. CAC was assessed in asymptomatic individuals by multidetector computed tomography. Anthropometric parameters and metabolic profiles were also recorded. Subjects were divided into four fasting glucose groups. Participants with a history of CVD or diabetes mellitus were excluded. Correlation between FPG and CAC scores, CAC score categories, and association between CAC score and FPG categories. Of 1112 participants, 346 (34.2%) had a CAC score > 0. FPG values in the IFG patients were positively but weakly correlated with CAC scores (r=0.099, P=.001). The incidence of CAC differed according to FPG level (P =110 mg/dL had a significantly higher risk of CAC than did subjects with normal fasting glucose (110.

  5. Prediction of the difficulty level in a standardized reading comprehension test: contributions from cognitive psychology and psychometrics.

    Directory of Open Access Journals (Sweden)

    Brizuela, Armel

    2013-07-01

    Full Text Available This research seeks to identify possible predictors of the difficulty level of reading comprehension items used in a standardized psychometric test for university admission. Several potential predictors of difficulty were proposed, namely, propositional density, negations, grammatical structure, vocabulary difficulty, presence of enhancement elements (words highlighted typographically, item abstraction level and degree of similarity between correct option and relevant text to resolve the item. By Linear Logistic Test Model (Fisher, 1973 it was found that the number of propositions, the syntactic structure, and fundamentally, the presence of difficult words contributed to the prediction of the item difficulty level.

  6. What Subject Matter Knowledge Do Second-Level Teachers Need to Know to Teach Trigonometry? An Exploration and Case Study

    Science.gov (United States)

    Walsh, Richard; Fitzmaurice, Olivia; O'Donoghue, John

    2017-01-01

    This study reports on the level of trigonometry Subject Matter Knowledge (SMK) of third and final-year pre-service second-level mathematics teachers () at an Irish third-level institution. The aim of the study was to determine if this sample of prospective teachers has an appropriate level of SMK to teach second-level trigonometric concepts. The…

  7. Teachers Sourcebook for Extensive Reading

    Science.gov (United States)

    Jacobs, George; Farrell, Thomas S. C.

    2012-01-01

    The best way for students to learn to read and to come to love reading is--surprise, surprise--by reading in quantity. Unfortunately, many of today's students read far too little. This lack of time spent reading is particularly unfortunate, as reading constitutes a bedrock skill, essential in all subject areas. Thus, we teachers need to devote…

  8. Metacognitive reading strategies in learning disability: Relations between usage level, academic self-efficacy and self-concept

    Directory of Open Access Journals (Sweden)

    Alev Girli

    2017-09-01

    Full Text Available The purpose of this study is to investigate the relationship between the usage levels of metacognitive reading strategies by students diagnosed with specific learning disability (SLD, academic self-efficacy and the concept of self, in comparison to their typically developing (TD peers. The data to be used in the study were collected using the Metacognitive Awareness of Reading Strategies Inventory, the Academic Self-efficacy Scale, the Piers-Harris Children’s Self-concept Scale and the Demographics Information Form. The study was conducted among a total of 119 students in the fifth,sixth, seventh and eighth grades in İzmir Province, including 59 students diagnosed with SLD and 60 TD students. Considering the results of the study, in comparison to TD students, students diagnosed with SLD were significantly inadequate in terms of the usage levels of metacognitive reading strategies, levels of academic self-efficacy, and the intelligence/school subdimensions of the concept of self.

  9. Associations between subjective symptoms and serum immunoglobulin E levels during Asian dust events.

    Science.gov (United States)

    Otani, Shinji; Onishi, Kazunari; Mu, Haosheng; Hosoda, Takenobu; Kurozawa, Youichi; Ikeguchi, Masahide

    2014-07-29

    Asian dust is a seasonal meteorological phenomenon caused by the displacement of atmospheric pollutants from the Mongolian and Chinese deserts. Although the frequency of Asian dust events and atmospheric dust levels have steadily increased in the eastern Asia region, the effects on human health remain poorly understood. In the present study, the impact of Asian dust on human health was determined in terms of allergic reactions. A total of 25 healthy volunteers were tested for a relationship between serum immunoglobulin E (IgE) levels and subjective symptoms during a 3-day Asian dust event recorded in April 2012. They filled daily questionnaires on the severity of nasal, pharyngeal, ocular, respiratory, and skin symptoms by a self-administered visual analog scale. Serum levels of non-specific IgE and 33 allergen-specific IgE molecules were analyzed. Spearman rank-correlation analysis revealed significant positive associations between nasal symptom scores and 2 microbial-specific IgE levels (Penicillium and Cladosporium). Microbes migrate vast distances during Asian dust events by attaching themselves to dust particles. Therefore, some of these symptoms may be associated with type 1 allergic reactions to certain type of microbes.

  10. Serum uric acid level and its association with cardiometabolic risk factors in prediabetic subjects

    Directory of Open Access Journals (Sweden)

    Bijan Iraj

    2014-01-01

    Full Text Available Background: Excess serum uric acid (UA accumulation can lead to various diseases. Increasing evidences reveal that UA may have a key role in the pathogenesis of metabolic syndrome. Little is known about the associations of UA levels with cardiometabolic risk factors in prediabetic individuals. This study was designed to evaluate the association between UA and cardiometabolic risk factors in prediabetic subjects with family history of diabetes compared with those with normal glucose tolerance (NGT. Materials and Methods: In a cross-sectional setting, a sample containing 643 (302 prediabetic subjects and 341 normal of the first-degree relatives of diabetic patients aged 35-55-years old were investigated. Samples were assessed in prediabetic and normal groups using glucose tolerance categories. Prediabetes was defined based on American Diabetes Association (ADA criteria. Body weight and height, systolic and diastolic blood pressure (SBP and DBP, UA, creatinine (Cr, albumin (Alb, fasting blood glucose (FBG, hemoglobin A1c (HbA1c, and lipid profiles were measured and compared between two groups. Results: Prediabetic persons were older and obese than normal persons. Also, prediabetic persons (5.2 ± 1.3 mg/dl had significantly higher UA than normal persons (4.9 ± 1.4 mg/dl (P 1, P < 0.05 associated with glucose tolerance categories. This association remained statistically significant after adjusting the effects of age and BMI. Also, the association between glucose tolerance categories and UA were positively significant in both genders. Conclusion: High UA level was associated with some cardiometabolic risk factors in prediabetic individuals compared with normal person. UA level was also a significant predictor for prediabetes condition.

  11. Write/erase stress relaxation effect on data-retention and read-disturb errors in triple-level cell NAND flash memory with round-robin wear-leveling

    Science.gov (United States)

    Deguchi, Yoshiaki; Kobayashi, Atsuro; Takeuchi, Ken

    2017-04-01

    This study analyzes the influence of the interval of time (t S-P) between write/erase endurance stress and programming the final data for the data-retention and read-disturb error evaluations in 1X nm triple-level cell (TLC) NAND flash memories. During the interval of time after the write/erase endurance stresses, electrons are de-trapped from the tunnel dielectric. Eventually, the data-retention error decreases in read-“cold” data which is infrequently read. By introducing long t S-P, e.g., 3 h, with round-robin wear-leveling, the bit error rate (BER) of the read-cold data can be decreased by 47%. Moreover, in read-“hot” data which is frequently read, the BER decreases because V TH-down errors are decreased by introducing long t S-P in over 600 read cycles, while the BER does not decrease in case of the smaller read cycles (<600) because V TH-up errors increase during the read operations. This work introduces the mechanism of the V TH-down error in read-“hot” data. The measured BER of the read-hot data decreases by 74% by introducing optimal t S-P with round-robin wear-leveling.

  12. Invariance levels across language versions of the PISA 2009 reading comprehension tests in Spain.

    Science.gov (United States)

    Elosua Oliden, Paula; Mujika Lizaso, Josu

    2013-01-01

    The PISA project provides the basis for studying curriculum design and for comparing factors associated with school effectiveness. These studies are only valid if the different language versions are equivalent to each other. In Spain, the application of PISA in autonomous regions with their own languages means that equivalency must also be extended to the Spanish, Galician, Catalan and Basque versions of the test. The aim of this work was to analyse the equivalence among the four language versions of the Reading Comprehension Test (PISA 2009). After defining the testlet as the unit of analysis, equivalence among the language versions was analysed using two invariance testing procedures: multiple-group mean and covariance structure analyses for ordinal data and ordinal logistic regression. The procedures yielded concordant results supporting metric equivalence across all four language versions: Spanish, Basque, Galician and Catalan. The equivalence supports the estimated reading literacy score comparability among the language versions used in Spain.

  13. Relationship between high normal TSH levels and metabolic syndrome components in type 2 diabetic subjects with euthyroidism

    Directory of Open Access Journals (Sweden)

    Lilit Petrosyan

    2015-09-01

    Conclusion: In type 2 diabetic subjects with biochemical euthyroidism we found significant association between high normal TSH levels and components of metabolic syndrome. High normal TSH levels were associated with more number of subjects with glycemic goal (HbA1c >7%.

  14. Bilingual Reading.

    Science.gov (United States)

    Garganta, Soledad; Ramirez, Inez

    This report discusses the importance of bilingual reading instruction for limited English speaking ability (LESA) students, and careful testing of their language dominance and reading levels. Bilingual students, and English- and Spanish-dominant students from the Fabens Independent School District, Grades K-13, were tested for the data reported…

  15. Coenzyme Q10, carotenoid, tocopherol, and retinol levels in cord plasma from multiethnic subjects in Hawaii

    Science.gov (United States)

    Franke, AA; Lai, J.F.; Morrison, C.M.; Pagano, I.; Li, X; Halm, B.M.; Soon, R.; Custer, L.J.

    2015-01-01

    Coenzyme Q10 (Q10), carotenoids, tocopherols, and retinol are the major circulating lipid-phase micronutrients (LPM) known to help mitigate oxidative damage and prevent chronic diseases. However, the functions of these compounds in newborns are little understood. This is due, in part, to the paucity of studies reporting their concentrations in this population. We measured Q10, carotenoids, tocopherols, and retinol in cord plasma from 100 multiethnic subjects living in Hawaii using HPLC with diode array and electrochemical detection. Appropriate internal standards were used including, for the first time, custom designed oxidized (UN10) and reduced (UL10) Q10 analogues. These compounds reflected the oxidation of UL10 to UN10 that occurred during sample processing and analysis and thus permitted accurate adjustments of natively circulating Q10 levels. All LPM measured were much lower in cord than in peripheral plasma. Cord plasma levels of total carotenoids, tocopherols, and retinol were approximately 10-fold, 3- to 5-fold and 1.5- to 3-fold lower than those in children or women. Cord plasma levels of total Q10 (TQ10; median, 113 ng/mL) were approximately 2-fold or 7- to 9-fold lower than peripheral plasma levels of neonates or children and adults, respectively. In contrast, the UN10/TQ10 ratio was substantially higher in cord (24%) than in peripheral plasma of children (3 – 4%) or adults (9%). Among the 5 ethnic groups in our cohort, no differences were observed in the levels of UN10, UL10, or TQ10. However, significant differences in many of the LPM were observed between ethnicities. More research is needed to explain these phenomena. PMID:23829202

  16. Coenzyme Q10, carotenoid, tocopherol, and retinol levels in cord plasma from multiethnic subjects in Hawaii.

    Science.gov (United States)

    Franke, A A; Lai, J F; Morrison, C M; Pagano, I; Li, X; Halm, B M; Soon, R; Custer, L J

    2013-09-01

    Coenzyme Q10 (Q10), carotenoids, tocopherols, and retinol are the major circulating lipid-phase micronutrients (LPM) known to help mitigate oxidative damage and prevent chronic diseases. However, the functions of these compounds in newborns are little understood. This is due, in part, to the paucity of studies reporting their concentrations in this population. We measured Q10, carotenoids, tocopherols, and retinol in cord plasma from 100 multiethnic subjects living in Hawaii using HPLC with diode array and electrochemical detection. Appropriate internal standards were used including, for the first time, custom designed oxidized (UN10) and reduced (UL10) Q10 analogues. These compounds reflected the oxidation of UL10 to UN10 that occurred during sample processing and analysis and thus permitted accurate adjustments of natively circulating Q10 levels. All LPM measured were much lower in cord than in peripheral plasma. Cord plasma levels of total carotenoids, tocopherols, and retinol were approximately 10-fold, 3- to 5-fold and 1.5- to 3-fold lower than those in children or women. Cord plasma levels of total Q10 (TQ10; median, 113 ng/mL) were approximately 2-fold or 7- to 9-fold lower than peripheral plasma levels of neonates or children and adults, respectively. In contrast, the UN10/TQ10 ratio was substantially higher in cord (24%) than in peripheral plasma of children (3-4%) or adults (9%). Among the 5 ethnic groups in our cohort, no differences were observed in the levels of UN10, UL10, or TQ10. However, significant differences in many of the LPM were observed between ethnicities. More research is needed to explain these phenomena.

  17. Does the Motor Level of the Paretic Extremities Affect Balance in Poststroke Subjects?

    Directory of Open Access Journals (Sweden)

    Kamal Narayan Arya

    2014-01-01

    Full Text Available Background. Poststroke impairment may lead to fall and unsafe functional performance. The underlying mechanism for the balance dysfunction is unclear. Objective. To analyze the relation between the motor level of the affected limbs and balance in poststroke subjects. Method. A prospective, cross-sectional, and nonexperimental design was conducted in a rehabilitation institute. A convenience sample of 44 patients was assessed for motor level using Brunnstrom recovery stage (BRS and Fugl-Meyer Assessment: upper (FMA-UE and lower extremities (FMA-LE. The balance was measured by Berg Balance Scale (BBS, Postural Assessment Scale for Stroke Patients (PASS, and Functional Reach Test (FRT. Results. BRS showed moderate correlation with BBS (ρ=0.54 to 0.60; P<0.001, PASS (r=0.48 to 0.64; P<0.001 and FRT (ρ=0.48 to 0.59; P<0.001. FMA-UE also exhibited moderate correlation with BBS (ρ=0.59; P<0.001 and PASS (ρ=0.60; P<0.001. FMA-LE showed fair correlation with BBS (ρ=0.50; P=0.001 and PASS (ρ=0.50; P=0.001. Conclusion. Motor control of the affected limbs plays an important role in balance. There is a moderate relation between the motor level of the upper and lower extremities and balance. The findings of the present study may be applied in poststroke rehabilitation.

  18. Self-Concept Predicts Academic Achievement Across Levels of the Achievement Distribution: Domain Specificity for Math and Reading.

    Science.gov (United States)

    Susperreguy, Maria Ines; Davis-Kean, Pamela E; Duckworth, Kathryn; Chen, Meichu

    2017-09-18

    This study examines whether self-concept of ability in math and reading predicts later math and reading attainment across different levels of achievement. Data from three large-scale longitudinal data sets, the Avon Longitudinal Study of Parents and Children, National Institute of Child Health and Human Development-Study of Early Child Care and Youth Development, and Panel Study of Income Dynamics-Child Development Supplement, were used to answer this question by employing quantile regression analyses. After controlling for demographic variables, child characteristics, and early ability, the findings indicate that self-concept of ability in math and reading predicts later achievement in each respective domain across all quantile levels of achievement. These results were replicated across the three data sets representing different populations and provide robust evidence for the role of self-concept of ability in understanding achievement from early childhood to adolescence across the spectrum of performance (low to high). © 2017 The Authors. Child Development © 2017 Society for Research in Child Development, Inc.

  19. A Continuous Learning and Developmental Reading Program. Elementary Curriculum Guide.

    Science.gov (United States)

    Hedlund, Sue; And Others

    GRADES OR AGES: Grades K-6. SUBJECT MATTER: Reading. ORGANIZATION AND PHYSICAL APPEARANCE: This guide is organized according to grade levels. Materials for K-6 have been organized under four broad color-coded topics: Kindergarten, Word Attack Skills, Comprehension, and Research Reading Levels. Each topic for each grade level is divided into…

  20. Behaviour of the buccal crestal bone levels after immediate placement of implants subjected to immediate loading.

    Science.gov (United States)

    Lemes, H deP; Sartori, I A deM; Cardoso, L C; Ponzoni, D

    2015-03-01

    The aim of this study was to measure changes in buccal alveolar crestal bone levels after immediate placement and loading of dental implants with Morse taper prosthetic abutments after tooth extraction. This study followed the STROBE guidelines regarding prospective cohort studies. The sample comprised 12 patients with a mean age of 45 years, in whom a central or upper lateral incisor was indicated for extraction. Prior to extraction, computed tomography (CT) analysis was carried out to assess the presence of the buccal bone crest. CT scans were performed at 24 h and at 6 months after immediate implant placement and immediate loading. The distance from the most apical point of the implant platform to the buccal bone crest was assessed at the two time points. The buccal bone crest height was evaluated at three points in the mesio-distal direction: (1) the centre point of the alveolus, (2) 1mm mesial to the centre point, and (3) 1 mm distal to the centre point. The values obtained were subjected to statistical analysis, comparing the distances from the bone crest to the implant platform for the two time points. After 6 months there was a statistically significant, non-uniform reduction in height at the level of the crest of the buccal bone in the cervical direction. It is concluded that the buccal bone crest of the immediate implants that replaced the maxillary incisors underwent apical resorption when subjected to immediate loading. Copyright © 2014 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  1. Effects of a fibre-enriched milk drink on insulin and glucose levels in healthy subjects

    Directory of Open Access Journals (Sweden)

    Pilvi Taru K

    2009-10-01

    Full Text Available Abstract Background The glycaemic response to foods is dependent on the quality and content of carbohydrates. Carbohydrates in the form of dietary fibre have favourable effects on insulin and glucose metabolism and may help to control energy intake. Dairy products have a relatively low carbohydrate content, and most of the carbohydrate is in the form of lactose which causes gastrointestinal symptoms in part of the population. In order to avoid these symptoms, dairy products can be replaced with lactose-free dairy products which are on the market in many parts of the world. However, the effects of lactose-free products on insulin and glucose metabolism have not been studied. Methods In the present study, we investigated the effects of 1 a lactose-free milk drink, 2 a novel fibre-enriched, fat- and lactose-free milk drink and 3 normal fat-free milk on serum glucose and insulin levels and satiety using a randomized block design. Following an overnight fast, 26 healthy volunteers ingested 200 ml of one of these drinks on three non-consecutive days. Insulin and glucose levels and subjective satiety ratings were measured before the ingestion of the milk product and 20, 40, 60, 120 and 180 minutes after ingestion. The responses were calculated as the area under the curve subtracted by the baseline value (AUC minus baseline. Results The insulin response was significantly lower for the fibre-enriched milk drink than it was for the other milk products (AUC, P = 0.007. There were no differences in the response for glucose or in the AUC for the subjective satiety ratings between the studied milk products. Conclusion The present results suggest that this novel milk drink could have positive effects on insulin response.

  2. Subjective assessment of cochlear implant users' signal-to-noise ratio requirements for different levels of wireless device usability.

    Science.gov (United States)

    Julstrom, Stephen; Kozma-Spytek, Linda

    2014-01-01

    In order to better inform the development and revision of the American National Standards Institute C63.19 and American National Standards Institute/Telecommunications Industry Association-1083 hearing aid compatibility standards, a previous study examined the signal strength and signal (speech)-to-noise (interference) ratio needs of hearing aid users when using wireless and cordless phones in the telecoil coupling mode. This study expands that examination to cochlear implant (CI) users, in both telecoil and microphone modes of use. The purpose of this study was to evaluate the magnetic and acoustic signal levels needed by CI users for comfortable telephone communication and the users' tolerance relative to the speech levels of various interfering wireless communication-related noise types. Design was a descriptive and correlational study. Simulated telephone speech and eight interfering noise types presented as continuous signals were linearly combined and were presented together either acoustically or magnetically to the participants' CIs. The participants could adjust the loudness of the telephone speech and the interfering noises based on several assigned criteria. The 21 test participants ranged in age from 23-81 yr. All used wireless phones with their CIs, and 15 also used cordless phones at home. There were 12 participants who normally used the telecoil mode for telephone communication, whereas 9 used the implant's microphone; all were tested accordingly. A guided-intake questionnaire yielded general background information for each participant. A custom-built test control box fed by prepared speech-and-noise files enabled the tester or test participant, as appropriate, to switch between the various test signals and to precisely control the speech-and-noise levels independently. The tester, but not the test participant, could read and record the selected levels. Subsequent analysis revealed the preferred speech levels, speech (signal)-to-noise ratios, and the

  3. Pleasure Reading and Reading Rate Gains

    Science.gov (United States)

    Beglar, David; Hunt, Alan

    2014-01-01

    This study investigated the effects of (a) the amount of pleasure reading completed, (b) the type of texts read (i.e., simplified or unsimplified books), and (c) the level of simplified texts read by 14 Japanese university students who made the largest reading rate gains over one academic year. The findings indicated that the participants who made…

  4. ¿Leen en forma voluntaria y recreativa los niños que logran un buen nivel de Comprensión Lectora? Do children who achieve a high level of Reading Comprehension read voluntarily and for recreation?

    Directory of Open Access Journals (Sweden)

    Mónica Valdés

    2013-11-01

    Full Text Available This study aims at determining the reading habits of 4th Grade students (4th Primary who reach an advanced level of reading comprehension. They were evaluated in the 2011 SIMCE test, in Chile. A survey about reading behaviors was conducted in a sample of 107 students from two schools in Talca, Maule region. In this study were items were evaluated: various behaviors associated with reading such as reading habits, defined as behaviors linked with the number of books read voluntarily and the taste for reading; frequency of use of the library and the priority of reading within the student’s free time; type of support utilized for reading and the role of parents in motivating their children to read. The results show that reaching a good level of reading comprehension does not ensure good reading habits or the enjoyment and pleasure of reading. The study also shows that students rarely use the school library and the low reading motivation they get from their parents.Este estudio tiene como objetivo conocer los hábitos lectores de los alumnos de 4° Básico (4° de Primaria que alcanzan un nivel de comprensión lectora avanzado, evaluado en la prueba Sistema de Medición de la Calidad de la Educación (SIMCE en Chile, en 2011. El estudio se realizó con una muestra de 107 alumnos que respondieron una encuesta y que pertenecen a dos colegios de la comuna de Talca, región del Maule. Fueron evaluadas distintas conductas asociadas a la lectura como el hábito lector, definido como las conductas asociadas a cantidad de libros leídos en forma voluntaria, el gusto por la lectura, la frecuencia en el uso de la biblioteca, el lugar que ocupa la lectura dentro del tiempo libre, el tipo de soporte utilizado para leer y el rol de los padres en la motivación por la lectura de sus hijos. Los resultados muestran que el hecho de alcanzarun buen nivel de comprensión lectora no asegura los buenos hábitos lectores, el gusto por la lectura y el leer por placer. Se

  5. The Effects of Visual Art Integration on Reading at the Elementary Level. A Review of Literature

    Science.gov (United States)

    McCarty, Kristine A.

    2007-01-01

    Although visual art is considered a subject deemed by the federal government as part of the core curriculum, many elementary schools do not include this subject into the current core curriculum of studies. This review of literature provides insight through current qualitative and quantitative studies on the effectiveness of including visual art…

  6. Reading Comprehension Level and Development in Native and Language Minority Adolescent Low Achievers: Roles of Linguistic and Metacognitive Knowledge and Fluency

    Science.gov (United States)

    Trapman, Mirjam; van Gelderen, Amos; van Schooten, Erik; Hulstijn, Jan

    2017-01-01

    In a longitudinal design, we measured 50 low-achieving adolescents' reading comprehension development from Grades 7 to 9. There were 24 native Dutch and 26 language minority students. In addition, we assessed the roles of (a) linguistic knowledge, (b) metacognitive knowledge, and (c) reading fluency in predicting both the level and growth of…

  7. Using Eye Tracking to Observe Differential Effects of Repeated Readings for Second-grade Students as a Function of Achievement Level

    Science.gov (United States)

    Zawoyski, Andrea M.; Ardoin, Scott P.; Binder, Katherine S.

    2015-01-01

    Repeated readings (RR) is an evidence-based instructional technique in which students read the same text multiple times. Currently, little is known about how effects of RR may differ based on students' achievement levels. Eye tracking provides a means for closely examining instructional effects because it permits measurement of subtle changes that…

  8. Venous plasma levels of endothelin-1 are not altered immediately after nitroglycerin infusion in healthy subjects

    DEFF Research Database (Denmark)

    Thomsen, L L; Iversen, Helle Klingenberg; Emmeluth, C

    1995-01-01

    before and immediately (5-30 s) after 80 min infusion of NTG (glyceryl trinitrate) or saline in 12 healthy subjects. On two different days separated by at least 1 week, NTG in four different doses, 0.015, 0.25, 1.0, and 2.0 micrograms. kg-1. min-1, or placebo (isotonic saline) was infused successively...... for 20 min each dose. During the infusion blood pressure and heart rate were measured. NTG infusion significantly decreased systolic blood pressure from 112.4 to 103.4 mmHg and pulse pressure from 39.3 to 29.5 mmHg. Heart rate increased from 62.7 to 73.1 beats. min-1. No changes in endothelin-1 plasma...... levels were induced by NTG infusion (2.4 pg.ml-1 before NTG vs. 2.7 pg.ml-1 after NTG) and placebo infusion also did not affect plasma endothelin-1. It is concluded that venous plasma levels of endothelin-1 are not altered immediately after NTG infusion....

  9. [The biopolitical production "impaired" subjects within the scope of "Action T4" - a re-reading of "I accuse"].

    Science.gov (United States)

    Offermann, Stefan

    2013-01-01

    The history of the Nazi "euthanasia programme" named "Aktion T4" has been examined from a biopolitical perspective for some time. However, these studies have not focused on the analytics of biopolitical practices of subjectivization as an essential element of the Foucaultian concept. The use of such a theoretical approach can be used in combination with new and substantial empirical research results. The Heidelberg DFG research programme evaluated the "T4" medical records statistically in order to conclusively determine which features had significant importance for selection by the "T4" experts. The inability to work or having an incurable mental illness were the criteria by which psychiatrists and "T4" experts subjectivized patients as "lives not worth living". Considering these new results and a biopolitical approach as starting point, it is time to reconsider the Nazi "euthanasia" propaganda movie "Ich klage an" ("I Accuse", 1941). When scholars began to study the production process of the movie in the 1980s, they looked at the narrative and the movie characters from an instrumental perspective. In other words, they examined how the "T4" protagonists and filmmakers sought to create a film which affected the viewers' opinion in a specific way intentionally influenced by them. According to that line of thought, the character Hanna was neglected because she was considered to be the morally inoffensive disguise of the intended propaganda massage. However, two works from the 1990s which were gender history-oriented finally focused on Hanna and the way the film narrative turns her into a subject "not worth living". Based on these considerations, this article states its thesis. The criteria of the film to subjectivize Hanna share many basic characteristics with those of the subjectivization process of the "T4" victims. To prove this statement, the analytics of the movie are combined with the results of the DFG project. Through the combination of both types of sources

  10. Changes in endotoxin levels in T2DM subjects on anti-diabetic therapies

    Directory of Open Access Journals (Sweden)

    Kumar Sudhesh

    2009-04-01

    Full Text Available Abstract Introduction Chronic low-grade inflammation is a significant factor in the development of obesity associated diabetes. This is supported by recent studies suggesting endotoxin, derived from gut flora, may be key to the development of inflammation by stimulating the secretion of an adverse cytokine profile from adipose tissue. Aims The study investigated the relationship between endotoxin and various metabolic parameters of diabetic patients to determine if anti-diabetic therapies exerted a significant effect on endotoxin levels and adipocytokine profiles. Methods Fasting blood samples were collected from consenting Saudi Arabian patients (BMI: 30.2 ± (SD5.6 kg/m2, n = 413, consisting of non-diabetics (ND: n = 67 and T2DM subjects (n = 346. The diabetics were divided into 5 subgroups based on their 1 year treatment regimes: diet-controlled (n = 36, metformin (n = 141, rosiglitazone (RSG: n = 22, a combined fixed dose of metformin/rosiglitazone (met/RSG n = 100 and insulin (n = 47. Lipid profiles, fasting plasma glucose, insulin, adiponectin, resistin, TNF-α, leptin, C-reactive protein (CRP and endotoxin concentrations were determined. Results Regression analyses revealed significant correlations between endotoxin levels and triglycerides (R2 = 0.42; p 2 = 0.10; p 2 = 0.076; p 2 = 0.032; p 2 = 0.055; p Conclusion We conclude that sub-clinical inflammation in T2DM may, in part, be mediated by circulating endotoxin. Furthermore, that whilst the endotoxin and adipocytokine profiles of diabetic patients treated with different therapies were comparable, the RSG group demonstrated significant differences in both adiponectin and endotoxin levels. We confirm an association between endotoxin and serum insulin and triglycerides and an inverse relationship with HDL. Lower endotoxin and higher adiponectin in the groups treated with RSG may be related and indicate another mechanism for the effect of RSG on insulin sensitivity.

  11. Acute effects of traditional Japanese alcohol beverages on blood glucose and polysomnography levels in healthy subjects

    Directory of Open Access Journals (Sweden)

    Megumi Kido

    2016-04-01

    Full Text Available Background. Alcohol consumption is a lifestyle factor associated with type 2 diabetes. This relationship is reportedly different depending on the type of alcohol beverage. The purpose of this study was to examine the acute effects of traditional Japanese alcohol beverages on biochemical parameters, physical and emotional state, and sleep patterns. Methods. Six healthy subjects (three men and three women; age, 28.8 ± 9.5 years; body mass index, 21.4 ± 1.6 kg/m2 consumed three different types of alcohol beverages (beer, shochu, and sake, each with 40 g ethanol or mineral water with dinner on different days in the hospital. Blood samples were collected before and 1, 2, and 12 h after drinking each beverage, and assessments of physical and emotional state were administered at the same time. In addition, sleep patterns and brain waves were examined using polysomnography. Results. Blood glucose levels at 1 h and the 12-h area under the curve (AUC value after drinking shochu were significantly lower than that with water and beer. The 12-h blood insulin AUC value after drinking shochu was significantly lower than that with beer. Blood glucose × insulin level at 1 h and the 2-h blood glucose × insulin AUC value with shochu were significantly lower than that with beer. The insulinogenic indexes at 2 h with beer and sake, but not shochu, were significantly higher than that with water. The visual analogue scale scores of physical and emotional state showed that the tipsiness levels with beer, shochu, and sake at 1 h were significantly higher than that with water. These tipsiness levels were maintained at 2 h. The polysomnography showed that the rapid eye movement (REM sleep latency with shochu and sake were shorter than that with water and beer. Conclusions. Acute consumption of alcohol beverages with a meal resulted in different responses in postprandial glucose and insulin levels as well as REM sleep latency. Alcohol beverage type should be taken into

  12. Acute effects of traditional Japanese alcohol beverages on blood glucose and polysomnography levels in healthy subjects.

    Science.gov (United States)

    Kido, Megumi; Asakawa, Akihiro; Koyama, Ken-Ichiro K; Takaoka, Toshio; Tajima, Aya; Takaoka, Shigeru; Yoshizaki, Yumiko; Okutsu, Kayu; Takamine, Kazunori T; Sameshima, Yoshihiro; Inui, Akio

    2016-01-01

    Background. Alcohol consumption is a lifestyle factor associated with type 2 diabetes. This relationship is reportedly different depending on the type of alcohol beverage. The purpose of this study was to examine the acute effects of traditional Japanese alcohol beverages on biochemical parameters, physical and emotional state, and sleep patterns. Methods. Six healthy subjects (three men and three women; age, 28.8 ± 9.5 years; body mass index, 21.4 ± 1.6 kg/m(2)) consumed three different types of alcohol beverages (beer, shochu, and sake, each with 40 g ethanol) or mineral water with dinner on different days in the hospital. Blood samples were collected before and 1, 2, and 12 h after drinking each beverage, and assessments of physical and emotional state were administered at the same time. In addition, sleep patterns and brain waves were examined using polysomnography. Results. Blood glucose levels at 1 h and the 12-h area under the curve (AUC) value after drinking shochu were significantly lower than that with water and beer. The 12-h blood insulin AUC value after drinking shochu was significantly lower than that with beer. Blood glucose × insulin level at 1 h and the 2-h blood glucose × insulin AUC value with shochu were significantly lower than that with beer. The insulinogenic indexes at 2 h with beer and sake, but not shochu, were significantly higher than that with water. The visual analogue scale scores of physical and emotional state showed that the tipsiness levels with beer, shochu, and sake at 1 h were significantly higher than that with water. These tipsiness levels were maintained at 2 h. The polysomnography showed that the rapid eye movement (REM) sleep latency with shochu and sake were shorter than that with water and beer. Conclusions. Acute consumption of alcohol beverages with a meal resulted in different responses in postprandial glucose and insulin levels as well as REM sleep latency. Alcohol beverage type should be taken into consideration

  13. An Exploration of Academic Reading Proficiency at the University Level: A Cross-Sectional Study of 848 Undergraduates

    Science.gov (United States)

    Gorzycki, Meg; Howard, Pamela; Allen, Diane; Desa, Geoffrey; Rosegard, Erik

    2016-01-01

    Academic reading proficiently is characterized by the ability to perform cognitive tasks associated with interpreting text. Researchers developed an externally validated Informal Academic Reading Proficiency Test to gauge undergraduates' academic reading proficiency. A cross-sectional study of 23 classes completed the reading test in 2014. This…

  14. The Effects of an Extensive Reading Program on Improving English as Foreign Language Proficiency in University Level Education

    Science.gov (United States)

    Alzu'bi, Mohammad Akram

    2014-01-01

    This study aimed at investigating the impact of extensive reading on improving reading proficiency. The study tried to find the effect of ER on EFL student's reading, vocabulary and grammar. The researcher designed two instruments; a program based on the extensive reading strategy and general test. Forty-one university students who study English…

  15. Cooccurrence of problems in activity level, attention, psychosocial adjustment, reading and writing in children with developmental coordination disorder.

    Science.gov (United States)

    Tseng, Mei-Hui; Howe, Tsu-Hsin; Chuang, I-Ching; Hsieh, Ching-Lin

    2007-12-01

    The purpose of this paper was to investigate the cooccurrence of problems in activity level, attention, reading, writing and psychosocial adjustment of children with developmental coordination disorder (DCD). A parent-report questionnaire, the Developmental Coordination Disorder Questionnaire - Chinese version (DCDQ-C), was used to screen first to third graders from 13 mainstream schools in Taipei. Two standardized motor tests were then administered to those who scored below 10% on the DCDQ-C. Tests of activity level, attention, reading, writing and psychosocial adjustment were then administered to this sample. Thirty-eight children identified as DCD, 32 as suspect for DCD and 82 as normal comparison were included in the final sample. Multivariate analysis of variance comparing the three groups (DCD, suspect DCD, and comparison) revealed that both children with DCD and suspect for DCD obtained significantly poorer scores on measures of attention and reading, and were more hyperactive than comparison children. Children with DCD and suspect for DCD were also reported to have more internalizing and social problems than children without motor problems. No significant differences, however, were noted between children with different degree of motor coordination problems (categorized as DCD and suspect for DCD) on any measure. Furthermore, a high percentage of children in both the DCD and suspect groups fell in the clinical range of attention, activity level and psychosocial adjustment problems. The results revealed a high risk for these problems in nonreferred children with motor coordination problems. The high percentage of clinical range behavioral problems warrants attention of clinicians who work with children with motor coordination difficulties to the need to promote early identification and referral.

  16. Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects.

    Science.gov (United States)

    Strajhar, P; Schmid, Y; Liakoni, E; Dolder, P C; Rentsch, K M; Kratschmar, D V; Odermatt, A; Liechti, M E

    2016-03-01

    Lysergic acid diethylamide (LSD) is a serotonin 5-hydroxytryptamine-2A (5-HT2A ) receptor agonist that is used recreationally worldwide. Interest in LSD research in humans waned after the 1970s, although the use of LSD in psychiatric research and practice has recently gained increasing attention. LSD produces pronounced acute psychedelic effects, although its influence on plasma steroid levels over time has not yet been characterised in humans. The effects of LSD (200 μg) or placebo on plasma steroid levels were investigated in 16 healthy subjects using a randomised, double-blind, placebo-controlled, cross-over study design. Plasma concentration-time profiles were determined for 15 steroids using liquid-chromatography tandem mass-spectrometry. LSD increased plasma concentrations of the glucocorticoids cortisol, cortisone, corticosterone and 11-dehydrocorticosterone compared to placebo. The mean maximum concentration of LSD was reached at 1.7 h. Mean peak psychedelic effects were reached at 2.4 h, with significant alterations in mental state from 0.5 h to > 10 h. Mean maximal concentrations of cortisol and corticosterone were reached at 2.5 h and 1.9 h, and significant elevations were observed 1.5-6 h and 1-3 h after drug administration, respectively. LSD also significantly increased plasma concentrations of the androgen dehydroepiandrosterone but not other androgens, progestogens or mineralocorticoids compared to placebo. A close relationship was found between plasma LSD concentrations and changes in plasma cortisol and corticosterone and the psychotropic response to LSD, and no clockwise hysteresis was observed. In conclusion, LSD produces significant acute effects on circulating steroids, especially glucocorticoids. LSD-induced changes in circulating glucocorticoids were associated with plasma LSD concentrations over time and showed no acute pharmacological tolerance. © 2016 British Society for Neuroendocrinology.

  17. Plasma levels and urinary excretion of amino acids by subjects with renal calculi.

    Science.gov (United States)

    Atanassova, Stoyanka Slavcheva; Panchev, P; Ivanova, M

    2010-05-01

    Plasma levels and urinary amino acid excretions were estimated by high-performance liquid chromatography in 15 control subjects and 36 stone formers (SFs) classified according to the stone type: (1) 22 cases with calcium oxalate stones; (2) four cases with pure uric acid stones; (3) 10 cases with magnesium-ammonium phosphate stones, either pure or mixed with apatite. Some types of stones (namely oxalate and uric acid calculi) are mainly formed as a result of a metabolic deficiency that may affect the amino acid metabolism, and thus may be reflected in the urinary amino acid pattern. Data demonstrated clearly that there is a general tendency towards decreased amino acid excretions in all SFs with all types of stones. As a whole, one can observe a higher percentage of patients with calcium oxalate and phosphate calculosis, who have low urine excretions of amino acids; about 50% are the SFs with lower urine excretion of serine, glycine, taurine and i-leucine; the high percentage of patients with CaOX calculi shows lower urine excretions of tyrosine and ornithine.

  18. Serum antioxidant capacity and peroxide level of seven healthy subjects after consumption of different foods

    Directory of Open Access Journals (Sweden)

    Maura N. Laus

    2016-12-01

    Full Text Available This article reports experimental data related to the research article entitled “Different effectiveness of two pastas supplemented with either lipophilic or hydrophilic/phenolic antioxidants in affecting serum as evaluated by the novel Antioxidant/Oxidant Balance approach” (M.N. Laus, M. Soccio, M. Alfarano, A. Pasqualone, M.S. Lenucci, G. Di Miceli, D. Pastore, 2016 [1]. Antioxidant status of blood serum of seven healthy subjects was evaluated during four hours after consumption of two functional pastas, supplemented with either bran oleoresin or bran water extract obtained from durum wheat. For comparison, the effect of a non-supplemented reference pasta was also evaluated, as well as the effects of glucose, of the wheat grain dietary supplement Lisosan G, and of the reference pasta consumed together with Lisosan G. Serum antioxidant status was evaluated by measuring both the serum antioxidant capacity, using LOX-FL, ORAC and TEAC methods, and the serum oxidant status, assessed as peroxide level.

  19. Absorption spectrum of a two-level system subjected to a periodic pulse sequence

    Science.gov (United States)

    Fotso, H. F.; Dobrovitski, V. V.

    2017-06-01

    We investigate how the quantum control of a two-level system (TLS) coupled to photons can modify and tune the TLS's photon absorption spectrum. Tuning and controlling the emission and the absorption are of great interest, e.g., for the development of efficient interfaces between stationary and flying qubits in modern architectures for quantum computation and quantum communication. We consider periodic pulse control, where the TLS is subjected to a periodic sequence of the near-resonant Rabi driving pulses, each pulse implementing a 180∘ rotation. For small interpulse delays, the absorption spectrum features a pronounced peak of stimulated emission at the pulse frequency, similar satellite peaks with smaller spectral weights, and the net absorption peaks on the sides. As long as the detuning between the carrier frequency of the driving and the TLS transition frequency remains moderate, this spectral shape shows little change. Therefore, the pulse control allows shifting the absorption peak to a desired position and locks the overall absorption spectrum to the carrier frequency of the driving pulses. A detailed description of the spectrum and its evolution as a function time, the interpulse spacing, and the detuning is presented.

  20. Fasting Ghrelin Levels Are Decreased in Obese Subjects and Are Significantly Related With Insulin Resistance and Body Mass Index

    Directory of Open Access Journals (Sweden)

    Dimitrios Papandreou

    2017-10-01

    CONCLUSION: Obese subjects have low fasting ghrelin levels that they are significantly related to insulin resistance and body mass index. More prospective studies are needed to establish the role of ghrelin in the pathogenesis of human obesity.

  1. The Feeling Dimension in Reading.

    Science.gov (United States)

    Ediger, Marlow

    The feeling dimension of students cannot be ignored in teaching and learning situations. Feelings are there and must not be ignored. Reading stresses word recognition, comprehension of subject matter at diverse levels of complexity, and application of what has been learned. A major ingredient so frequently left out is student appreciation of the…

  2. Reading Logs: Integrating Extensive Reading with Writing Tasks

    Science.gov (United States)

    Lyutaya, Tatiana

    2011-01-01

    Extensive reading motivates learners to read a large number of texts on a wide range of topics because the students themselves select the reading material based upon its relevance to their interests, knowledge, and experience. Students read texts that match their language level, and they choose the time and place to read. Extensive reading "is…

  3. Leptin Levels and Nutritional Status of Indigenous Tepehuán and Mestizo Subjects in Durango, Mexico

    Science.gov (United States)

    Delgadillo Guzmán, Dealmy; Marchat Marchau, Laurence Annie; Reyes, José L.; Loera Castañeda, Verónica; Sosa Macías, Martha; García Vivas, Jessica; Asseff, Ismael Lares

    2014-01-01

    The aim of this study was to assess differences in nutritional status and their association with circulating leptin levels in the indigenous Tepehuán people of Mezquital Durango and Mestizo populations of Durango City, Mexico. A group of 128 volunteers aged 18 through 59 years were recruited for the study: 60 indigenous Tepehuán from Mezquital and 68 Mestizo individuals from Durango City. The classification of nutritional status was through body mass index (BMI). Clinical evaluations, including anthropometry and lipid profiles, were performed to ascertain the health of the participants. Circulating leptin levels were determined in blood samples after at 08 hours of fasting. The healthy subjects were classified according to BMI: 32 Tepehuán and 30 Mestizo subjects were of normal weight (NW), and 28 Tepehuán and 38 Mestizo subjects were overweight or obese (OW/O). Both NW and OW/O Tepehuán subjects showed lower leptin concentrations than the comparable Mestizo subjects. Statistical analysis showed a negative Pearson's correlation (r = −0.5; P < 0.05) between BMI and leptin levels in NW Tepehuán subjects, but no significant correlation was found in other groups. The differences found in Tepehuán compared with Mestizo subjects might be explained by poor nutritional status, which leads to scarce adipose tissue and low levels of leptin synthesis. Leptin concentration and its relationship to BMI are associated with ethnicity. PMID:24825928

  4. How Are Researching and Reading Interwieved during Retrieval from Hierarchically Structured Documents?

    DEFF Research Database (Denmark)

    Hertzum, Morten; Lalmas, M.; Frøkjær, Erik

    2001-01-01

    in the structure. Based on an experiment where 83 subjects solved 20 tasks each, we find that the subjects spend at least one third of their time reading, irrespective of whether the system they use offers browsing and/or querying. The subjects prefer reading the text in chunks that span multiple levels...

  5. Modifications of sleep structure induced by increasing levels of acoustic perturbation in normal subjects.

    Science.gov (United States)

    Terzano, M G; Parrino, L; Fioriti, G; Orofiamma, B; Depoortere, H

    1990-07-01

    In each non-REM (NREM) sleep stage, the aggregation of the arousal-related phasic events permits identification of periods of arousal fluctuation (cyclic alternating pattern or CAP) and periods of long-lasting arousal stability (non-CAP or NCAP). As the ratio CAP time to NREM sleep time (CAP/NREM) measures the instability of arousal during sleep, any perturbing event determines an increase of CAP/NREM. On the basis of these premises, 6 healthy volunteers underwent 5 sleep recordings at increasing intensities of sound pressure level (basal condition followed by continuous white noise at 45 dBA, 55 dBA, 65 dBA and 75 dBA, respectively). Besides a remarkable enhancement of CAP/NREM (P less than 0.00001), acoustic perturbation induced a significant linear increase of waking time after sleep onset, stage 2, NREM sleep, stage shifts and a significant linear decrease of stage 4, deep sleep, REM sleep and total sleep time. At each step of environmental disturbance, the values of the CAP ratio were consistent with the gradual changes of sleep organization. Although the Multiple Sleep Latency Test was unremarkable during the day following the sleep recording, CAP/NREM was significantly correlated with the personal evaluation of sleep quality (P less than 0.01). Through this model of transient situational insomnia it was possible to outline different degrees of subjective complaint depending on 3 ranges of CAP/NREM. A crucial role of CAP in the pathophysiological mechanisms of clinical insomnia is hypothesized.

  6. Estimation of physical activity levels using cell phone questionnaires: a comparison with accelerometry for evaluation of between-subject and within-subject variations.

    Science.gov (United States)

    Bexelius, Christin; Sandin, Sven; Trolle Lagerros, Ylva; Litton, Jan-Eric; Löf, Marie

    2011-09-25

    Physical activity promotes health and longevity. Further elaboration of the role of physical activity for human health in epidemiological studies on large samples requires accurate methods that are easy to use, cheap, and possible to repeat. The use of telecommunication technologies such as cell phones is highly interesting in this respect. In an earlier report, we showed that physical activity level (PAL) assessed using a cell phone procedure agreed well with corresponding estimates obtained using the doubly labeled water method. However, our earlier study indicated high within-subject variation in relation to between-subject variations in PAL using cell phones, but we could not assess if this was a true variation of PAL or an artifact of the cell phone technique. Our objective was to compare within- and between-subject variations in PAL by means of cell phones with corresponding estimates using an accelerometer. In addition, we compared the agreement of daily PAL values obtained using the cell phone questionnaire with corresponding data obtained using an accelerometer. PAL was measured both with the cell phone questionnaire and with a triaxial accelerometer daily during a 2-week study period in 21 healthy Swedish women (20 to 45 years of age and BMI from 17.7 kg/m² to 33.6 kg/m²). The results were evaluated by fitting linear mixed effect models and descriptive statistics and graphs. With the accelerometer, 57% (95% confidence interval [CI] 40%-66%) of the variation was within subjects, while with the cell phone, within-subject variation was 76% (95% CI 59%-83%). The day-to-day variations in PAL observed using the cell phone questions agreed well with the corresponding accelerometer results. Both the cell phone questionnaire and the accelerometer showed high within-subject variations. Furthermore, day-to-day variations in PAL within subjects assessed using the cell phone agreed well with corresponding accelerometer values. Consequently, our cell phone

  7. Communication subjective assessments of patients undergoing compulsory treatment with the severity of negative symptoms and cognitive functioning level

    Directory of Open Access Journals (Sweden)

    Kabanov T.N.

    2015-04-01

    Full Text Available The article presents the results of studies on the relationship of subjective assessments of the mentally ill with the severity of negative symptoms and cognitive functioning level. The features of patients perception of various aspects of compulsory treatment and subjective satisfaction with treatment. In a study of 94 male patients with a diagnosis of organic mental disorder and schizophrenia was used diagnostic system, consisting of patopsihologicheskogo study, formal survey map, the scale of assessment of negative symptoms SANS, questionnaire symptom levels SCL-90, self-existing problems, as well as - in Test authoring tool sheet to treatment and hospital stay (VG Bulygin, Kabanov, TN, 2011. The differences in subjective assessments of aspects of compulsory treatment and social functioning of patients with varying degrees of severity of negative symptoms and dependence of subjective assessments of the level of cognitive functioning.

  8. Vitamin D levels in subjects with or without chronic kidney disease among Veterans with diabetes in North East United States

    Science.gov (United States)

    Yaturu, Subhashini; Youngberg, Barbara; Zdunek, Sonya

    2017-01-01

    AIM To evaluate the prevalence of vitamin D deficiency and its relation to diabetes and kidney disease in Veterans residing in the North East United States (VISN 2). METHODS In this retrospective study, we used data from the computerized patient record system at Stratton Veterans Administration Medical Center at Albany, NY (VHA) for those patients who had 25-hydroxyvitamin D levels and 1,25 (OH) vitamin D levels measured between 2007 and 2010. We collected demographic information including age, sex, body mass index and race; clinical data including diabetes, hypertension and CAD; and laboratory data including calcium, creatinine and parathyroid hormone (PTH) (intact). Vitamin D deficiency is defined as a serum 25-hydroxyvitamin D level of less than 20 ng/mL (50 nmol/L), and insufficiency is defined as a serum 25-hydroxyvitamin D level of 20 to 30 ng/mL (50 to 75 nmol/L). RESULTS Data was available for approximately 68000 subjects. We identified 64144 subjects for analysis after exclusion of duplicates. Among them, 27098 had diabetes. The mean age of subjects with diabetes was 68 ± 11 with a mean body mass index (BMI) of 32 ± 7 and duration of diabetes of 5.6 ± 3.2 years. The mean 25 (OH) vitamin D level among subjects with diabetes was 27 ± 11.6. There was no significant difference in 25 (OH) vitamin D levels between subjects with diabetes and glomerular filtration rate (e-GFR) < 60 compared to those with e-GFR ≥ 60. As expected, subjects with e-GFR < 60 had significantly lower 1,25 (OH) vitamin D levels and significantly elevated PTH-intact. Of the 64144 subjects, 580 had end-stage renal disease. Of those, 407 had diabetes and 173 did not. Vitamin D levels in both groups were in the insufficiency range and there was no significant difference irrespective of presence or absence of diabetes. Subjects with vitamin D levels less than 20 ng/mL had a higher BMI and elevated PTH, and higher HbA1C levels compared to those with vitamin D levels more than 20 ng

  9. Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding.

    Directory of Open Access Journals (Sweden)

    Shubha Vij

    2016-04-01

    Full Text Available We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer, a tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical and genetic mapping along with shared synteny from closely related fish species to derive a chromosome-level assembly with a contig N50 size over 1 Mb and scaffold N50 size over 25 Mb that span ~90% of the genome. The population structure of L. calcarifer species complex was analyzed by re-sequencing 61 individuals representing various regions across the species' native range. SNP analyses identified high levels of genetic diversity and confirmed earlier indications of a population stratification comprising three clades with signs of admixture apparent in the South-East Asian population. The quality of the Asian seabass genome assembly far exceeds that of any other fish species, and will serve as a new standard for fish genomics.

  10. Texting, Reading, and Other Daily Habits Associated with Adolescents' Literacy Levels

    Science.gov (United States)

    Zebroff, Dmitri; Kaufman, David

    2017-01-01

    The level of functional illiteracy in the North American context, among others, appears to be reaching epidemic levels. The necessary linguistic and intellectual tools required to adequately function in our complex, highly-literate societies are not being sufficiently developed in many of our homes or schools. The findings from the present study…

  11. The Danish version of the Radner Reading Chart: design and empirical testing of sentence optotypes in subjects of varying educational background.

    Science.gov (United States)

    Munch, Inger Christine; Jørgensen, Astrid-Helene Ravn; Radner, Wolfgang

    2016-03-01

    To develop 28 short texts to be used as sentence optotypes in a Danish version of the Radner Reading Chart for the measurement of reading acuity and speed. Forty-six short texts of comparable lexical and grammatical difficulty were constructed. The short texts were tested together with two longer reference texts in 100 persons with visual acuity 6/6, of which 50 were university students (age: 24.7 ± 3.1 years, 36% males) and 50 were blue-collar workers (37.2 ± 13.4 years, 54% males). Study parameters were mean reading speed and error rate per participant, and mean reading time, variance and number of errors per short text. The students read the short texts faster than the blue-collar workers (184 ± 21.4 words per minute (wpm) versus 163 ± 26.3 wpm, p errors was eight. Twenty-eight short texts were selected for sentence optotypes with mean reading times between 4.6 s and 5.2 s, a mean standard deviation of 1.2 s or less and a number of errors of 17 per 100 persons or less. Reading time uniformity in the Danish version of the Radner Reading Chart was comparable to that of the original German version. Education had an influence on reading performance that may warrant stratification for this parameter when reading tests are used in clinical trials. © 2015 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  12. A teaching intervention for reading laboratory experiments in college-level introductory chemistry

    Science.gov (United States)

    Kirk, Maria Kristine

    The purpose of this study was to determine the effects that a pre-laboratory guide, conceptualized as a "scientific story grammar," has on college chemistry students' learning when they read an introductory chemistry laboratory manual and perform the experiments in the chemistry laboratory. The participants (N = 56) were students enrolled in four existing general chemistry laboratory sections taught by two instructors at a women's liberal arts college. The pre-laboratory guide consisted of eight questions about the experiment, including the purpose, chemical species, variables, chemical method, procedure, and hypothesis. The effects of the intervention were compared with those of the traditional pre-laboratory assignment for the eight chemistry experiments. Measures included quizzes, tests, chemistry achievement test, science process skills test, laboratory reports, laboratory average, and semester grade. The covariates were mathematical aptitude and prior knowledge of chemistry and science processes, on which the groups differed significantly. The study captured students' perceptions of their experience in general chemistry through a survey and interviews with eight students. The only significant differences in the treatment group's performance were in some subscores on lecture items and laboratory items on the quizzes. An apparent induction period was noted, in that significant measures occurred in mid-semester. Voluntary study with the pre-laboratory guide by control students precluded significant differences on measures given later in the semester. The groups' responses to the survey were similar. Significant instructor effects on three survey items were corroborated by the interviews. The researcher's students were more positive about their pre-laboratory tasks, enjoyed the laboratory sessions more, and were more confident about doing chemistry experiments than the laboratory instructor's groups due to differences in scaffolding by the instructors.

  13. Subject-level differences in reported locations of cutaneous tactile and nociceptive stimuli

    NARCIS (Netherlands)

    Steenbergen, P.; Buitenweg, Jan R.; Trojan, J.; Klaassen, Bart; Veltink, Petrus H.

    2012-01-01

    Recent theoretical advances on the topic of body representations have raised the question whether spatial perception of touch and nociception involve the same representations. Various authors have established that subjective localizations of touch and nociception are displaced in a systematic

  14. Evaluation of serum C-reactive protein levels in subjects with aggressive and chronic periodontitis and comparison with healthy controls

    Directory of Open Access Journals (Sweden)

    Aruna Kanaparthy

    2012-01-01

    Results : Overall, the mean CRP levels were high in subjects with generalized aggressive and chronic periodontitis compared with controls. This was found to be statistically significant. A statistically significant difference (P = 0.012 was found in the CRP level between groups I and II and between groups II and III, and between groups I and III. Conclusion: The results of the present study indicated an increase in serum CRP levels in subjects with generalized aggressive periodontitis and chronic periodontitis as compared with the controls.

  15. Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects.

    Science.gov (United States)

    Wu, Dong-Feng; Yin, Rui-Xing; Aung, Lynn Htet Htet; Li, Qing; Yan, Ting-Ting; Zeng, Xiao-Na; Huang, Ke-Ke; Huang, Ping; Wu, Jin-Zhen; Pan, Shang-Ling

    2012-01-13

    Acyl-CoA:cholesterol acyltransferase (ACAT) is a key enzyme in cellular cholesterol homeostasis and in atherosclerosis. The cellular cholesterol efflux correlated with serum high-density lipoprotein cholesterol (HDL-C) concentrations has shown to be impaired in hyperlipidemic mice. The present study was carried out to clarify the association of ACAT-1 rs1044925 single nucleotide polymorphism (SNP) and serum lipid levels in the hyperlipidemic subjects. A total of 821 unrelated subjects (hyperlipidemia, 476; normolipidemia, 345) aged 15-80 were included in the study. Genotyping of the ACAT-1 rs1044925 SNP was performed by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis, and then confirmed by direct sequencing. There was no significant difference in the genotypic and allelic frequencies of ACAT-1 rs1044925 SNP between the normolipidemic and hyperlipidemic subjects. The levels of total cholesterol (TC), HDL-C and apolipoprotein (Apo) AI in hyperlipidemic subjects were different between the AA and AC/CC genotypes in male but not in female (P ACAT-1 rs1044925 SNP in male hyperlipidemic subjects had higher serum TC, HDL-C and ApoAI levels than the C allele noncarriers. There is a sex (male)-specific association of ACAT-1 rs1044925 SNP and serum HDL-C and ApoAI levels in the hypercholesterolemic subjects.

  16. Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects

    Directory of Open Access Journals (Sweden)

    Wu Dong-Feng

    2012-01-01

    Full Text Available Abstract Background Acyl-CoA:cholesterol acyltransferase (ACAT is a key enzyme in cellular cholesterol homeostasis and in atherosclerosis. The cellular cholesterol efflux correlated with serum high-density lipoprotein cholesterol (HDL-C concentrations has shown to be impaired in hyperlipidemic mice. The present study was carried out to clarify the association of ACAT-1 rs1044925 single nucleotide polymorphism (SNP and serum lipid levels in the hyperlipidemic subjects. Methods A total of 821 unrelated subjects (hyperlipidemia, 476; normolipidemia, 345 aged 15-80 were included in the study. Genotyping of the ACAT-1 rs1044925 SNP was performed by polymerase chain reaction and restriction fragment length polymorphism combined with gel electrophoresis, and then confirmed by direct sequencing. Results There was no significant difference in the genotypic and allelic frequencies of ACAT-1 rs1044925 SNP between the normolipidemic and hyperlipidemic subjects. The levels of total cholesterol (TC, HDL-C and apolipoprotein (Apo AI in hyperlipidemic subjects were different between the AA and AC/CC genotypes in male but not in female (P Conclusions The present study shows that the C allele carriers of ACAT-1 rs1044925 SNP in male hyperlipidemic subjects had higher serum TC, HDL-C and ApoAI levels than the C allele noncarriers. There is a sex (male-specific association of ACAT-1 rs1044925 SNP and serum HDL-C and ApoAI levels in the hypercholesterolemic subjects.

  17. Primary School Pre-Service Teachers' Self-Assessed Competency Level of Teaching How to Read in Turkey

    Science.gov (United States)

    Çayir, Aybala

    2017-01-01

    Learning to read is an important step for a child's academic and social success. Meaningful and fluent reading skills are linked to children's progress in their thinking and criticizing abilities. The knowledge and skills required for effective reading are initially taught in primary schools. The main responsibility of primary school teachers' is…

  18. Predictors and Outcomes of Variability in Subjective Alcohol Intoxication among College Students: An Event-Level Analysis across Four Years

    Science.gov (United States)

    Quinn, Patrick D.; Fromme, Kim

    2010-01-01

    Background Individual differences in subjective alcohol intoxication, as measured by laboratory-based alcohol challenge, have been identified as a phenotypic risk factor for alcohol use disorders. Further, recent evidence indicates that subjective alcohol response is also associated with event-level physiological consequences among college students, including blackouts and hangovers. Methods The current investigation tested predictors of and outcomes associated with subjective intoxication in the natural drinking environment. In a preliminary laboratory alcohol-challenge study (N = 53), we developed a brief measure of subjective alcohol intoxication for use in event level research. Participating students in the principal study (N = 1,867; 63% female; 54% Caucasian) completed 30 days of Web-based self-monitoring in each of the four college years. Results In the principal study, Generalized Estimating Equation analyses revealed that both lighter drinking and a family history of alcohol problems predicted greater subjective intoxication after accounting for estimated blood alcohol concentration (eBAC). Moreover, greater subjective intoxication during a given drinking episode was associated with negative alcohol-related consequences, illicit drug use, and unsafe sex, and at higher eBACs, was associated with aggression, sex, and property crime. Students who on average experienced greater subjective intoxication were also more likely to experience negative consequences and engage in illicit drug use, sex, unsafe sex, and aggression. Conclusions These findings suggest that both within-person variability and between-person individual differences in subjective intoxication may be risk factors for adverse drinking outcomes at the event level. Intervention efforts aimed at reducing problems associated with collegiate drinking may benefit from consideration both of who experiences greater subjective intoxication and of the situations in which they are more likely to do so

  19. Reading Journal as A Way to Improve Students’ Comprehension toward A Textbook Reading Material

    Directory of Open Access Journals (Sweden)

    Menik Winiharti

    2014-11-01

    Full Text Available Reading journal is one way to record students’ independent learning based on text they read. This study was conducted to find out the students’ level of reading comprehension through some notes written in the reading journal, the extent to which the activity of writing reading journals improved students’ reading comprehension, whether the students got benefit from reading journal. There were 104 respondents coming from four different departments in Bina Nusantara University were asked to read a text related to the subject they learned in a certain session. Then they were assigned to write a journal that records the things they had read. When this task was finished, the lecturer ran a quiz containing related questions to check whether they really understood the content of the text. Afterwards, students were to fill in a questionnaire regarding their opinion on the impact of the reading journal toward their reading comprehension. The findings indicate that more than half of the participants appear to understand the material well, and the task plays a certain role in improving students’ understanding. The most crucial thing is that most students think they get benefit by writing the reading journal.

  20. Using Language-Experience to Teach Diagnostically at the Reading Readiness Level.

    Science.gov (United States)

    Christensen, K. Eleanor

    When used diagnostically at the readiness level, language-experience becomes an effective way to meet individual differences and to differentiate instruction in a group setting. For a 5- or 6-year old, school should be an exciting, happy, purposeful place, and language-experience lends itself well to such a setting. The first steps are to…

  1. Circulating CD36 and oxLDL levels are associated with cardiovascular risk factors in young subjects.

    Science.gov (United States)

    Ramos-Arellano, Luz E; Muñoz-Valle, José F; De la Cruz-Mosso, Ulises; Salgado-Bernabé, Aralia B; Castro-Alarcón, Natividad; Parra-Rojas, Isela

    2014-04-28

    Cardiovascular disease (CVD) results from a combination of abnormalities in lipoprotein metabolism, oxidative stress, chronic inflammation, and susceptibility to thrombosis. Atherosclerosis is the major cause of CVD. CD36 has been shown to play a critical role in the development of atherosclerotic lesions by its capacity to bind and promote endocytosis of oxidized low-density lipoprotein (oxLDL) and is implicated in the formation of foam cells. The purpose of this research was to evaluate whether there is an association of sCD36 and oxLDL levels with cardiovascular risk factors in young subjects. A total of 188 subjects, 18 to 25 years old, 133 normal-weight and 55 obese subjects from the state of Guerrero, Mexico were recruited in the study. The lipid profile and glucose levels were measured by enzymatic colorimetric assays. Enzyme-linked immunosorbant assays (ELISA) for oxLDL and sCD36 were performed. Statistical analyses of data were performed with Wilcoxon- Mann Whitney and chi-square tests as well as with multinomial regression. TC, LDL-C, TG, oxLDL and sCD36 levels were higher in obese subjects than in normal-weight controls, as well as, monocyte and platelet counts (P Obese subjects had 5.8 times higher risk of sCD36 in the third tertil (>97.8 ng/mL) than normal-weight controls (P = 0.014), and 7.4 times higher risk of oxLDL levels in third tertile (>48 U/L) than control group. The subjects with hypercholesterolemia, hypertriglyceridemia, fasting impaired LDL-C had a higher risk of oxLDL levels in the third tertile (>48 U/L) than the control group (P cardiovascular risk factors in young subjects and may be potential early markers for cardiovascular disease (CVD).

  2. Is fear perception special? Evidence at the level of decision-making and subjective confidence

    OpenAIRE

    Koizumi, Ai; Mobbs, Dean; Lau, Hakwan

    2016-01-01

    Fearful faces are believed to be prioritized in visual perception. However, it is unclear whether the processing of low-level facial features alone can facilitate such prioritization or whether higher-level mechanisms also contribute. We examined potential biases for fearful face perception at the levels of perceptual decision-making and perceptual confidence. We controlled for lower-level visual processing capacity by titrating luminance contrasts of backward masks, and the emotional intensi...

  3. The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels: a randomised controlled study

    Science.gov (United States)

    2013-01-01

    Background Previous animal studies have shown that Curcuma longa (turmeric) improves liver function. Turmeric may thus be a promising ingredient in functional foods aimed at improving liver function. The purpose of the study is to investigate the hepatoprotective effect of fermented turmeric powder (FTP) on liver function in subjects with elevated alanine transaminase (ALT) levels. Methods A randomised, double-blind, placebo-controlled trial was conducted between November 2010 and April 2012 at the clinical trial center for functional foods of the Chonbuk National University Hospital. The trial included 60 subjects, 20 years old and above, who were diagnosed mild to moderate elevated ALT levels between 40 IU/L and 200 IU/L. Sixty subjects were randomised to receive FTP 3.0 g per day or placebo 3.0 g per day for 12 weeks. The treatment group received two capsules of FTP three times a day after meals, for 12 weeks. The primary efficacy endpoint was change in the ALT levels in the two groups. The secondary efficacy endpoints included its effect on aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), total bilirubin (TB), and lipid profiles. Safety was assessed throughout the study using ongoing laboratory tests. Adverse events (AEs) were also recorded. Results Sixty subjects were randomised in the study (30 into the FTP group, 30 into the placebo group), and among them, twelve subjects were excluded from the analysis for protocol violation, adverse events or consent withdrawal. The two groups did not differ in baseline characteristics. After 12 weeks of treatment, 48 subjects were evaluated. Of the 48 subjects, 26 randomly received FTP capsules and 22 received placebo. The FTP group showed a significant reduction in ALT levels after 12 weeks of treatment compared with the placebo group (p = 0.019). There was also observed that the serum AST levels were significantly reduce in the FTP group than placebo group (p = 0.02). The GGT levels

  4. Regional Hippocampal Atrophy and Higher Levels of Plasma Amyloid-Beta Are Associated With Subjective Memory Complaints in Nondemented Elderly Subjects

    DEFF Research Database (Denmark)

    Cantero, Jose L; Iglesias, Juan E.; Van Leemput, Koen

    2016-01-01

    Background: Evidence suggests a link between the presence of subjective memory complaints (SMC) and lower volume of the hippocampus, one of the first regions to show neuropathological lesions in Alzheimer's disease. However, it remains unknown whether this pattern of hippocampal atrophy is region......Background: Evidence suggests a link between the presence of subjective memory complaints (SMC) and lower volume of the hippocampus, one of the first regions to show neuropathological lesions in Alzheimer's disease. However, it remains unknown whether this pattern of hippocampal atrophy...... volume differences in hippocampal subregions were further correlated with plasma Aβ levels and with objective memory performance. Results: Individuals with SMC exhibited significantly higher Aβ1-42 concentrations and lower volumes of CA1, CA4, dentate gyrus, and molecular layer compared with SMC......(-) participants. Regression analyses further showed significant associations between lower volume of the dentate gyrus and both poorer memory performance and higher plasma Aβ1-42 levels in SMC(+) participants. Conclusions: The presence of SMC, lower volumes of specific hippocampal regions, and higher plasma Aβ1...

  5. Relationship of plasma apolipoprotein M with proprotein convertase subtilisin-kexin type 9 levels in non-diabetic subjects

    DEFF Research Database (Denmark)

    Kappelle, Paul J W H; Lambert, Gilles; Dahlbäck, Björn

    2011-01-01

    PURPOSE: Apolipoprotein M (apoM) retards atherosclerosis development in murine models, and may be regulated by pathways involved in LDL metabolism. Proprotein convertase subtilisin-kexin type 9 (PCSK9) plays a key role in LDL receptor processing. We determined the extent to which plasma apo......M is related to PCSK9 levels in subjects with varying degrees of obesity. METHODS: We sought correlations between plasma apoM and PCSK9, measured using recently developed ELISAs, in 79 non-diabetic subjects. RESULTS: ApoM and PCSK9 levels were both correlated positively with total cholesterol, non-HDL...

  6. Teaching Reading

    Science.gov (United States)

    Day, Richard R.

    2013-01-01

    "Teaching Reading" uncovers the interactive processes that happen when people learn to read and translates them into a comprehensive easy-to-follow guide on how to teach reading. Richard Day's revelations on the nature of reading, reading strategies, reading fluency, reading comprehension, and reading objectives make fascinating…

  7. Effect of Salt Intake on Serum Glucagon-Like Peptide-1 Levels in Normotensive Salt-Sensitive Subjects

    Directory of Open Access Journals (Sweden)

    Wen-Ling Zheng

    2017-10-01

    Full Text Available Background/Aims: Excess dietary salt is a critical risk factor of salt-sensitive hypertension. Glucagon-like peptide-1 (GLP-1 , a gut incretin hormone, conferring benefits for blood pressure by natriuresis and diuresis. We implemented a randomized trial to verify the effect of altered salt intake on serum GLP-1 level in human beings. Methods: The 38 subjects were recruited from a rural community of Northern China. All subjects were sequentially maintained a baseline diet period for 3 days, a low-salt diet period for 7 days (3.0g/day of NaCl , and a high-salt diet period for additional 7 days (18.0g/day of NaCl. Results: Serum GLP-1 level increased significantly with the change from the baseline period to the low-salt diet period and decreased with the change from the low-salt to high-salt diet in normotensive salt-sensitive (SS but not salt-resistant (SR individuals. There was a significant inverse correlation between the serum GLP-1 level and the MAP in SS subjects. Inverse correlation between the serum GLP-1 level and 24-h urinary sodium excretion was also found among different dietary interventions in SS subjects. Conclusions: Our study indicates that variations in dietary salt intake affect the serum GLP-1 level in normotensive salt-sensitive Chinese adults.

  8. Similar to adiponectin, serum levels of osteoprotegerin are associated with obesity in healthy subjects.

    LENUS (Irish Health Repository)

    Ashley, David T

    2011-07-01

    An increase in serum osteoprotegerin (OPG) is associated with type 2 diabetes mellitus, the severity of vascular calcification, and coronary artery disease. Obesity is a risk factor for diabetes and cardiovascular disease, but little is known about the relationship between OPG and obesity. The purpose of this study was to determine if changes in body mass index (BMI) and insulin sensitivity influence circulating OPG in healthy subjects. A total of 100 subjects (36 lean, 41 overweight, and 23 obese) with normal glucose tolerance, blood pressure, and electrocardiogram stress test result volunteered for this study. Insulin sensitivity was estimated using a 2-hour oral glucose tolerance test with oral glucose insulin sensitivity analysis. Osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL),soluble receptor activator of nuclear factor-κβ ligand (sRANKL), and adiponectin were analyzed using commercially available enzyme-linked immunosorbent assays. Osteoprotegerin (P < .01) and adiponectin (P < .001) were significantly decreased in the obese compared with lean subjects. There was no significant difference between BMI categories for TRAIL or sRANKL. Controlling for age and sex, there was a significant correlation between OPG and adiponectin (r = 0.391, P < .001), BMI (r = -0.331, P < .001), waist circumference (r = -0.268, P < .01), homeostasis model assessment of insulin resistance (r = -0.222, P < .05), and oral glucose insulin sensitivity (r = 0.221, P < .05). Both OPG and adiponectin were negatively correlated with body weight, BMI, waist circumference, and fasting plasma insulin while being positively correlated with insulin sensitivity (P < .05). Controlling for age, sex, and BMI, TRAIL was positively related to fat mass (r = 0.373, P < .001) and waist circumference (r = 0.257, P < .05). In contrast to patients with type 2 diabetes mellitus, circulating OPG is lower in obese, but otherwise healthy subjects and is positively correlated

  9. Serum testosterone levels of HbSS (sickle cell disease male subjects in Lagos, Nigeria

    Directory of Open Access Journals (Sweden)

    Adediran Adewumi

    2011-08-01

    Full Text Available Abstract Background Infertility is a major problem in sickle cell disease patients, especially in males. In addition to low serum testosterone, other abnormalities involving the accessory sex organs, such as the seminal vesicles and the prostate gland, as well as marked decrease in ejaculate volume may be observed in male HbSS patients. Hence, the need to study the role of sex hormones as a cause of infertility in male HbSS patients. Methods An unmatched case-control study was performed using seventy-five consenting subjects from Lagos University Teaching Hospital. These included 47 patients with haemoglobin phenotype SS from the Sickle cell clinic and 28 volunteered medical students and members of staff with haemoglobin phenotype AA. Demographic data were obtained using a self-administered questionnaire. A total of 5 mls of blood was collected from each subject between 9.00 am & 11.am, and assayed for serum testosterone concentration. Results The concentrations of serum testosterone in HbSS patients ranged from 0.2 to 4.3 ng/ml with a mean of 1.28 ± 0.72 ng/ml whilst the values in HbAA controls ranged from 1.2 to 6.9 ng/ml with a mean of 2.63 ± 1.04 ng/ml. Seven (25.0% of the 28 controls had serum testosterone concentration lower than the quoted reference (normal range whereas 44 (93.6% of the 47 HbSS subjects had serum testosterone concentration lower than the reference range. Conclusion Overall, subjects with HbSS have significantly lower mean serum testosterone than HbAA controls.

  10. Correlation of Anxiety Levels between Temporomandibular Disorder Patients and Normal Subjects

    OpenAIRE

    Subhash Vasudeva; Asha Iyengar; Nagesh Seetaramaiah

    2014-01-01

    Background. Temporomandibular disorders (TMDs) are among the common musculoskeletal conditions affecting the individual. Anxiety plays an important role in the pathogenesis of TMD. Modern lifestyle and work environment bring to focus the role of anxiety in everyday life which is changing the demographics of diseases like TMD. This study compared the anxiety scores between TMD patients and normal subjects. Material and Methods. 505 individuals were included in the study who were divided into g...

  11. The Relationship Between the Serum Level of Vitamin D and Vitiligo: A Controlled Study on 300 Subjects.

    Science.gov (United States)

    Khurrum, Huma; AlGhamdi, Khalid M

    2016-01-01

    Low vitamin D levels have been associated with several autoimmune diseases. Vitiligo could be associated with low vitamin D levels. To determine the level of serum vitamin D in vitiligo patients compared to controls and reveal the possible association of vitamin levels with the pathogenesis of vitiligo. A case-controlled study was conducted. After excluding factors that may affect serum vitamin D levels, blood samples were taken from vitiligo patients and controls. The association between vitamin D levels and various vitiligo subgroups (duration of vitiligo, site of onset, age, etc) was measured and correlated. A total of 150 vitiligo patients, 90 (60%) males with a mean age of 30.6 ± 11.4 years, were recruited. The study also had 150 age- and gender-matched vitiligo-free control subjects. There was no significant difference in median serum vitamin D levels between the cases and the controls (P = .25). The serum levels of vitamin D of the vitiligo patients were found to be lower in males (P = .01), the younger age group (P = .01), and patients not treated with ultraviolet (UV) treatment (P = .01). There is no difference between the vitamin D levels of the vitiligo patients and the control subjects. However, deficiency of 25(OH)D levels within the vitiligo subgroups may be linked to younger age, male gender, short duration of vitiligo, and non-use of phototherapy. © The Author(s) 2015.

  12. The role of visual representation type, spatial ability, and reading comprehension in word problem solving: An item-level analysis in elementary school children

    NARCIS (Netherlands)

    Boonen, A.J.H.; van Wesel, F.; Jolles, J.; van der Schoot, M.

    2014-01-01

    This study examined the role of visual representation type, spatial ability, and reading comprehension in word problem solving in 128 sixth-grade students by using primarily an item-level approach rather than a test-level approach. We revealed that compared to students who did not make a visual

  13. Do Absence and Mobility (Transience Affect Reading Literacy Achievement?

    Directory of Open Access Journals (Sweden)

    Ratna Rintaningrum

    2015-06-01

    Full Text Available Reading literacy has been regarded as an important subject taught at the primary school level as it is the foundation for learning across all subject. Australia, as a developed country, has placed great emphasis on the importance of reading literacy in primary schools by establishing various educational policies and undertaking various programs, both for teachers and students, to improve the teaching of reading literacy in school. However, different students have different levels of skill in acquiring reading comprehension. The findings of some studies suggest that there are a number of reasons why some children perform better in reading literacy than others do. Absence and mobility are two factors that are considered to have effect on reading achievement. Both Australia, America and International studies have shown that there is negative relationship between absence, mobility and school achievement.

  14. Using competing speech to estimate articulatory automatization in children: the possible effect of masking level and subject grade.

    Science.gov (United States)

    Manning, W H; Scheer, B R

    1978-09-01

    In order to study the possible influence of masking level and subject grade on a procedure for determining a child's articulatory automatization (Manning et al., 1976) 47 first and second grade and 49 third and fourth grade children were administered the McDonald Deep Test of Articulation under one of five conditions of auditory masking (earphones only, or presentation of competing speech at 50, 60, 70, or 80 dB SPL). Results indicated no significant difference in subject performance across the factors of masking level and subject grade. The findings suggest that these factors do not appear to be critical in the clinical application of the suggested procedure for estimating children's automatization of newly acquired phonemes.

  15. Correlation of salivary cortisol level with obstructive sleep apnea syndrome in pediatric subjects.

    Science.gov (United States)

    Park, Chan-Soon; Guilleminault, Christian; Hwang, Se-Hwan; Jeong, Jong-Hyun; Park, Dong-Sun; Maeng, Jae-Hwan

    2013-10-01

    Obstructive sleep apnea syndrome (OSAS) is associated with stress system activation involving the hypothalamic-pituitary-adrenocortical (HPA) axis. The relationships among salivary cortisol, a measure of the HPA axis, and objective parameters of polysomnography (PSG) and subjective sleep symptoms were examined. Our prospective study enrolled 80 children who had a physical examination, underwent overnight PSG, and completed the Korean version of the modified pediatric Epworth sleepiness scale (KMPESS) and OSA-18 (KOSA-18) questionnaires. Saliva was collected at night before PSG and in the early morning after PSG. Subjects (N=80) were divided into control (n=32, apnea-hypopnea index [AHI] or =1) groups; the OSAS group was subdivided into mild (1 or =5) groups. Although salivary cortisol before PSG (n-sCor) did not show a significant change with OSAS severity, salivary cortisol after PSG (m-sCor) significantly decreased with OSAS severity. This decrease resulted in a salivary cortisol ratio (r-sCor) that was significantly different between the control group and the two OSAS subgroups. The m-sCor and sub-sCor of the total group as well as the m-sCor, sub-sCor, and r-sCor of the OSAS group were negatively related to the oxygen desaturation index (ODI). The m-sCor and r-sCor in the OSAS group also were related to subjective sleep symptoms (quality of life [QOL] by KOSA-18). Among the four salivary cortisol parameters, r-sCor was negatively associated with OSAS severity, ODI, and QOL (KOSA-18), which may indicate a chronically stressed HPA axis. These results demonstrate that salivary cortisol may be a useful biomarker of OSAS. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Information and Choice of A-Level Subjects: A Cluster Randomised Controlled Trial with Linked Administrative Data

    Science.gov (United States)

    Davies, Peter; Davies, Neil M.; Qiu, Tian

    2017-01-01

    We estimated the effects of an intervention which provided information about graduate wages to 5593 students in England, using a blinded cluster randomised controlled trial in 50 schools (registration: AEARCTR-0000468). Our primary outcome was students' choice of A-level subjects at age 16. We also recorded the students' expectations of future…

  17. Reflective Pedagogy: The Integration of Methodology and Subject-Matter Content in a Graduate-Level Course

    Science.gov (United States)

    Jakeman, Rick C.; Henderson, Markesha M.; Howard, Lionel C.

    2017-01-01

    This article presents a critical reflection on how we, instructors of a graduate-level course in higher education administration, sought to integrate theoretical and subject-matter content and research methodology. Our reflection, guided by autoethnography and teacher reflection, challenged both our assumptions about curriculum design and our…

  18. Explaining participation differentials in Dutch higher education : the impact of subjective success probabilities on level choice and field choice

    NARCIS (Netherlands)

    Tolsma, J.; Need, A.; Jong, U. de

    2010-01-01

    In this article we examine whether subjective estimates of success probabilities explain the effect of social origin, sex, and ethnicity on students’ choices between different school tracks in Dutch higher education. The educational options analysed differ in level (i.e. university versus

  19. Using E-Z reader to model the effects of higher level language processing on eye movements during reading

    National Research Council Canada - National Science Library

    Reichle, Erik D; Warren, Tessa; McConnell, Kerry

    2009-01-01

    Although computational models of eye-movement control during reading have been used to explain how saccadic programming, visual constraints, attention allocation, and lexical processing jointly affect...

  20. Reading charts in ophthalmology.

    Science.gov (United States)

    Radner, W

    2017-08-01

    A new generation of logarithmic reading charts has sparked interest in standardized reading performance analyses. Such reading charts have been developed according to the standards of the International Council of Ophthalmology. The print size progression in these calibrated charts is in accordance with the mathematical background of EN ISO 8596. These reading charts are: the Bailey-Lovie Word Reading Chart, the Colenbrander English Continuous Text Near Vision Cards, the Oculus Reading Probe II, the MNREAD Charts, the SKread Charts, and the RADNER Reading Charts. The test items used for these reading charts differ among the charts and are standardized to various extents. The Bailey-Lovie Charts, MNREAD Charts, SKread Charts, and RADNER Charts are also meant to measure reading speed and allow determination of further reading parameters such as reading acuity, reading speed based on reading acuity, critical print size, reading score, and logMAR/logRAD ratio. Such calibrated reading charts have already provided valuable insights into the reading performance of patients in many research studies. They are available in many languages and thus facilitate international communication about near visual performance. In the present review article, the backgrounds of these modern reading charts are presented, and their different levels of test-item standardization are discussed. Clinical research studies are mentioned, and a discussion about the immoderately high number of reading acuity notations is included. Using the logReading Acuity Determination ([logRAD] = reading acuity equivalent of logMAR) measure for research purposes would give reading acuity its own identity as a standardized reading parameter in ophthalmology.

  1. SUBJECT «NUMBER SYSTEMS» IN TWO-LEVELED FORMAT PREPARATION TEACHERS OF MATHEMATICS

    Directory of Open Access Journals (Sweden)

    V. I. Igoshin

    2017-01-01

    Full Text Available The aim of this article is to analyze the format of a two-leveled training – bachelor and master – future teachers of mathematics from the point of view of the content of mathematical material, which is to develop prospective teachers of mathematics at those two levels, shaping their professional competence.Methods. The study involves the theoretical methods: the analysis of pedagogical and methodical literature, normative documents; historical, comparative and logical analysis of the content of pedagogical mathematical education; forecasting, planning and designing of two-leveled methodical system of training of future teachers of mathematics.Results and scientific novelty. The level differentiation of the higher education system requires developing the appropriate curricula for undergraduate and graduate programs. The fundamental principle must be the principle of continuity – the magister must continue to deepen and broaden knowledge and skills, along with competences acquired, developed and formed on the undergraduate level. From these positions, this paper examines the course «Number Systems» – the most important in terms of methodology course for future mathematics teachers, and shows what content should be filled with this course at the undergraduate level and the graduate level. At the undergraduate level it is proposed to study classical number systems – natural, integer, rational, real and complex. Further extensions of the number systems are studied at the graduate level. The theory of numeric systems is presented as a theory of algebraic systems, arising at the intersection of algebra and mathematical logic. Here we study algebras over a field, division algebra over a field, an alternative algebra with division over the field, Jordan algebra, Lie algebra. Comprehension of bases of the theory of algebras by the master of the «mathematical education» profile will promote more conscious

  2. Controls on valley spacing in landscapes subject to rapid base-level fall

    Science.gov (United States)

    McGuire, Luke; Pelletier, John D.

    2015-01-01

    What controls the architecture of drainage networks is a fundamental question in geomorphology. Recent work has elucidated the mechanisms of drainage network development in steadily uplifting landscapes, but the controls on drainage-network morphology in transient landscapes are relatively unknown. In this paper we exploit natural experiments in drainage network development in incised Plio-Quaternary alluvial fan surfaces in order to understand and quantify drainage network development in highly transient landscapes, i.e. initially unincised low-relief surfaces that experience a pulse of rapid base-level drop followed by relative base-level stasis. Parallel drainage networks formed on incised alluvial-fan surfaces tend to have a drainage spacing that is approximately proportional to the magnitude of the base-level drop. Numerical experiments suggest that this observed relationship between the magnitude of base-level drop and mean drainage spacing is the result of feedbacks among the depth of valley incision, mass wasting and nonlinear increases in the rate of colluvial sediment transport with slope gradient on steep valley side slopes that lead to increasingly wide valleys in cases of larger base-level drop. We identify a threshold magnitude of base-level drop above which side slopes lengthen sufficiently to promote increases in contributing area and fluvial incision rates that lead to branching and encourage drainage networks to transition from systems of first-order valleys to systems of higher-order, branching valleys. The headward growth of these branching tributaries prevents the development of adjacent, ephemeral drainages and promotes a higher mean valley spacing relative to cases in which tributaries do not form. Model results offer additional insights into the response of initially unincised landscapes to rapid base-level drop and provide a preliminary basis for understanding how varying amounts of base-level change influence valley network morphology.

  3. Promoting the Reading Culture Towards Human Capital and Global Development

    Science.gov (United States)

    Olasehinde, M. O.; Akanmode, O. A.; Alaiyemola, A. T.; Babatunde, O. T.

    2015-01-01

    It is commonly agreed that a country cannot be fully developed without large-scale investment in her educational scheme since the breakthrough of a country is directly proportional to her educational level. Since the acquisition of effective reading skills has a positive effect on all school subjects, then reading is sine-qua-non for human capital…

  4. Developing Teachers' Capacity for Teaching Pupils' Initial Reading ...

    African Journals Online (AJOL)

    DrNneka

    Primary school teachers that teach English language /mother tongue were not equipped with the knowledge and skills to teach initial reading in these languages. ▫ Reading is not taught as a subject in the primary education system, particularly the state public schools. ▫ Teachers in the lower basic level lack knowledge of ...

  5. The Three-Level Synthesis of Standardized Single-Subject Experimental Data: A Monte Carlo Simulation Study.

    Science.gov (United States)

    Moeyaert, Mariola; Ugille, Maaike; Ferron, John M; Beretvas, S Natasha; Van den Noortgate, Wim

    2013-09-01

    Previous research indicates that three-level modeling is a valid statistical method to make inferences from unstandardized data from a set of single-subject experimental studies, especially when a homogeneous set of at least 30 studies are included ( Moeyaert, Ugille, Ferron, Beretvas, & Van den Noortgate, 2013a ). When single-subject data from multiple studies are combined, however, it often occurs that the dependent variable is measured on a different scale, requiring standardization of the data before combining them over studies. One approach is to divide the dependent variable by the residual standard deviation. In this study we use Monte Carlo methods to evaluate this approach. We examine how well the fixed effects (e.g., immediate treatment effect and treatment effect on the time trend) and the variance components (the between- and within-subject variance) are estimated under a number of realistic conditions. The three-level synthesis of standardized single-subject data is found appropriate for the estimation of the treatment effects, especially when many studies (30 or more) and many measurement occasions within subjects (20 or more) are included and when the studies are rather homogeneous (with small between-study variance). The estimates of the variance components are less accurate.

  6. Baseline cardiac troponin t levels are elevated in subjects with untreated diabetes mellitus

    DEFF Research Database (Denmark)

    Pareek, M; Nielsen, M L; Leósdóttir, M

    2015-01-01

    Objective: Cardiac troponins are biomarkers of myocardial injury and serve both diagnostic and prognostic purposes. Even mild elevations represent subclinical myocardial damage in the general population. The objective of this study was to investigate the relationship between glucometabolic status...... and cardiac troponin T in middle-aged or older apparently healthy subjects. Design and method: We examined cross-sectional associations between highsensitivity cardiac troponin T (hsTnT) and FPG categorized as normal fasting glucose (NFG: FPG/=7.0mmol/L), in 535 men and 226 women aged 56-79 years without.......26). After adjusting for age and sex, FPG category remained significantly predictive of hsTnT (B = 1.08 [95% confidence interval (CI), 0.56-1.59]; p hypertrophy (LVH...

  7. Event-level associations between objective and subjective alcohol intoxication and driving after drinking across the college years.

    Science.gov (United States)

    Quinn, Patrick D; Fromme, Kim

    2012-09-01

    Heavy episodic drinking is strongly associated with driving after drinking, yet there has been mixed evidence regarding whether the disinhibiting effects of alcohol intoxication contribute to the decision to drive after drinking. This investigation tested whether greater alcohol intoxication increased the probability of driving after drinking particularly during drinking episodes in which students experienced reduced subjective feelings of intoxication. A sample of 1,350 college students completed up to 30 days of web-based daily diary monitoring in each of 4 consecutive years. Participants reported daily on their alcohol consumption, subjective intoxication, and whether they drove after drinking on the previous day or night. In generalized estimating equation models, daily estimated blood alcohol concentration (eBAC) was more strongly associated with driving after drinking during episodes in which subjective intoxication was lower. That is, students were most likely to drive after drinking when they were objectively more intoxicated but perceived themselves as less intoxicated. These event-level associations did not change over time nor did they differ as a function of gender. Further, the effects persisted when predicting driving at eBACs above the legal limit for operating a motor vehicle. Greater subjective intoxication may serve to inhibit driving after drinking, particularly when students are objectively more intoxicated. In the absence of subjective intoxication, however, other salient pressures might impel driving after drinking. Prevention efforts should incorporate the importance of variability in subjective intoxication. PsycINFO Database Record (c) 2012 APA, all rights reserved.

  8. A Comparative Study of Vitamin D Levels in Persons with Hair Loss and Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Gh. Eshghi

    2015-04-01

    Full Text Available Introduction & Objectives: Alopecia or hair loss is defined as the loss of hair on the head or body. Despite the benign prognosis of hair loss, it has a clear impact on the quality of life of the patients who are involved. There are many reasons to explain the pathophysiology of hair loss. Among many nutritional factors, vitamin D deficiency may play a role in hair loss too. Active vitamin D or 1, 25 dihydroxy vitamin D has an effect on the expression of some genes in normal differentiation of epidermal cells and hair follicles. The purpose of this study was to determine the level of vitamin D in patients with hair loss compared with healthy controls. Materials & Methods: From 2014 to 2015, 70 patients were enrolled in this case-control study. Including 40 women and 30 men, the mean age was 31.2 ± 0.82 years in the case group, 33.8 ± 0.92 years in the control group. Groups were matched by sex, age and season of review. In the both groups, there were 20 women (57.1% and 15 men (42.5%. After the clinical diagno-sis of hair loss by the physician, patient's blood samples were sent for testing vitamin D levels by kits of a laboratory center. Results: Patients, compared with controls, had lower levels of vitamin D and there was signifi-cant relationship between hair loss and low levels of vitamin D (16.188±6.91 vs 20.37±7.47, and P=0.04. Female patients had lower levels of vitamin D, compared with controls and there was significant relationship between hair loss and low levels of vitamin D (14.14±5.8 vs 18.74±7.08 and P=0.03. The group of male patients had lower levels of vitamin D, but in comparison with the control group, no significant relationship was found. Conclusion: This study showed that, there is a relationship between vitamin D levels and hair loss in women. (Sci J Hamadan Univ Med Sci 2015; 22 (1:71-75

  9. Reflections on the development of an EFL reading programme for middle school students of varied levels of English

    Directory of Open Access Journals (Sweden)

    Barfield Randall

    2003-08-01

    Full Text Available This personal-experience article attempts to share with the reader an EFL reading and grammar programme that was designed in 2002 for a group of 12 to 14-year olds (6th and 7th graders whose English levels varied from almost nil to semiconversational. Multi-levels of English in any given group present a considerable challenge to either the EFL or ESL teacher, needless to say. More than one of these students exhibited evidence of a learning disability, not only in L2 but in L1 as well. For instance, transposition of letters (b instead of d and vice versa in both languages, poor spelling in L1 and L2, and in L2, writing on the level of a second or third- grade native speaker. A considerable number of these students had been forced to leave other, larger schools for academic and/or disciplinary reasons. So, this teacher swallowed then rolled up his sleeves to go to work (in fear of what the year would bring?. In other words, the teacher accepted the challenge. Key words: English-Teaching High School-Programs, Reading-Teaching-Programs, Books and Reading for Children-Teaching High School-Programs Este artículo de experiencia personal tiene como objetivo dar a conocer al lector un programa de EFL sobre lectura y gramática que fue diseñado en 2002 para un grupo de niños entre los 12 y 14 años de edad (grados 6 y 7, los cuales tenían niveles de inglés que variaban entre cero conocimiento del idioma y semi-conversacional. Los multi-niveles en inglés en cualquier grupo presentan un desafío considerable para el profesor de EFL o ESL. Adicionalmente, más de un estudiante demostró tener problemas de aprendizaje no sólo en L2 sino en L1. Por ejemplo, la transposición de letras (b en vez de d o viceversa en ambos idiomas, pobre ortografía en L1 y L2 y en L2 la escritura en un nivel igual al de un estudiante nativo que cursa segundo o tercero de primaria. Un número considerable de estudiantes han sido obligados a abandonar otros colegios

  10. Association of lipoprotein levels with mortality in subjects aged 50 + without previous diabetes or cardiovascular disease

    DEFF Research Database (Denmark)

    Bathum, Lise; Depont Christensen, René; Engers Pedersen, Lars

    2013-01-01

    This study aimed to investigate the association of lipoprotein and triglyceride levels with all-cause mortality in a population free from diabetes and cardiovascular disease (CVD) at baseline. The European Guidelines on cardiovascular disease prevention state that in general total cholesterol (TC...

  11. Thyroid peroxidase antibodies, levels of thyroid stimulating hormone and development of hypothyroidism in euthyroid subjects

    NARCIS (Netherlands)

    Roos, A.; Links, T.P.; de Jong-van den Berg, L.T.; Gans, R.O.; Wolffenbuttel, B.H.; Bakker, S.J.

    2010-01-01

    Objective: Thyroid peroxidase antibodies (TPOAbs) have been found to be related to the levels of thyroid stimulating hormone (TSH) and to predict future development of thyroid failure in selected populations. We investigated these relations in a euthyroid general population. Design: Cross-sectional

  12. Comparison of plasma endothelin levels between osteoporotic, osteopenic and normal subjects

    Directory of Open Access Journals (Sweden)

    Biçimoğlu Ali

    2005-09-01

    Full Text Available Abstract Background It has been demonstrated that endothelins (ET have significant roles in bone remodeling, metabolism and physiopathology of several bone diseases. We aimed to investigate if there was any difference between the plasma ET levels of osteoporotic patients and normals. Methods 86 patients (70 women and 16 men with a mean age of 62.6 (ranges: 51–90 years were included in this study. Patients were divided into groups of osteoporosis, osteopenia and normal regarding reported T scores of DEXA evaluation according to the suggestions of World Health Organization. According to these criteria 19, 43 and 24 were normal, osteopenic and osteoporotic respectively. Then total plasma level of ET was measured in all patients with monoclonal antibody based sandwich immunoassay (EIA method. One-way analysis of variance test was used to compare endothelin values between normals, osteopenics and osteoporotics. Results Endothelin total plasma level in patients was a mean of 98.36 ± 63.96, 100.92 ± 47.2 and 99.56 ± 56.6 pg/ml in osteoporotic, osteopenic and normal groups respectively. The difference between groups was not significant (p > 0.05. Conclusion No significant differences in plasma ET levels among three groups of study participants could be detected in this study.

  13. Is fear perception special? Evidence at the level of decision-making and subjective confidence.

    Science.gov (United States)

    Koizumi, Ai; Mobbs, Dean; Lau, Hakwan

    2016-11-01

    Fearful faces are believed to be prioritized in visual perception. However, it is unclear whether the processing of low-level facial features alone can facilitate such prioritization or whether higher-level mechanisms also contribute. We examined potential biases for fearful face perception at the levels of perceptual decision-making and perceptual confidence. We controlled for lower-level visual processing capacity by titrating luminance contrasts of backward masks, and the emotional intensity of fearful, angry and happy faces. Under these conditions, participants showed liberal biases in perceiving a fearful face, in both detection and discrimination tasks. This effect was stronger among individuals with reduced density in dorsolateral prefrontal cortex, a region linked to perceptual decision-making. Moreover, participants reported higher confidence when they accurately perceived a fearful face, suggesting that fearful faces may have privileged access to consciousness. Together, the results suggest that mechanisms in the prefrontal cortex contribute to making fearful face perception special. © The Author (2016). Published by Oxford University Press.

  14. Higher circulating levels of IGF-1 are associated with longer leukocyte telomere length in healthy subjects

    DEFF Research Database (Denmark)

    Barbieri, Michelangela; Paolisso, Giuseppe; Kimura, Masayuki

    2009-01-01

    Mutations that inhibit the insulin-like growth factor-1 (IGF-1) extend the lifespan of worms, flies and mice. However, it appears that relatively low circulating levels of IGF-1 in humans are associated with aging-related diseases and diminished longevity. As leukocyte telomere length (LTL) is os...

  15. Word-level reading achievement and behavioral inattention: exploring their overlap and relations with naming speed and phonemic awareness in a community sample of children.

    Science.gov (United States)

    Martinussen, Rhonda; Grimbos, Teresa; Ferrari, Julia L S

    2014-11-01

    This study investigated the contribution of naming speed and phonemic awareness to teacher inattention ratings and word-level reading proficiency in 79 first grade children (43 boys, 36 girls). Participants completed the cognitive and reading measures midway through the school year. Teacher ratings of inattention were obtained for each child at the same time point. A path analysis revealed that behavioral inattention had a significant direct effect on word reading proficiency as well as significant indirect effects through phonemic awareness and naming speed. For pseudoword reading proficiency, the effects of inattention were indirect only through phonemic awareness and naming speed. A regression analysis indicated that naming speed, but not phonemic awareness, was significantly associated with teacher inattention ratings controlling for word reading proficiency. The findings highlight the need to better understand the role of behavioral inattention in the development of emergent literacy skills and reading proficiency. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

    Directory of Open Access Journals (Sweden)

    van Eijk Kristel R

    2012-11-01

    Full Text Available Abstract Background The predominant model for regulation of gene expression through DNA methylation is an inverse association in which increased methylation results in decreased gene expression levels. However, recent studies suggest that the relationship between genetic variation, DNA methylation and expression is more complex. Results Systems genetic approaches for examining relationships between gene expression and methylation array data were used to find both negative and positive associations between these levels. A weighted correlation network analysis revealed that i both transcriptome and methylome are organized in modules, ii co-expression modules are generally not preserved in the methylation data and vice-versa, and iii highly significant correlations exist between co-expression and co-methylation modules, suggesting the existence of factors that affect expression and methylation of different modules (i.e., trans effects at the level of modules. We observed that methylation probes associated with expression in cis were more likely to be located outside CpG islands, whereas specificity for CpG island shores was present when methylation, associated with expression, was under local genetic control. A structural equation model based analysis found strong support in particular for a traditional causal model in which gene expression is regulated by genetic variation via DNA methylation instead of gene expression affecting DNA methylation levels. Conclusions Our results provide new insights into the complex mechanisms between genetic markers, epigenetic mechanisms and gene expression. We find strong support for the classical model of genetic variants regulating methylation, which in turn regulates gene expression. Moreover we show that, although the methylation and expression modules differ, they are highly correlated.

  17. Relationship Between Self-Injurious Behaviors and Levels of Aggression in Children and Adolescents Who Were Subject to Medicolegal Examination.

    Science.gov (United States)

    Ozsoy, Sait; Kara, Koray; Teke, Hacer Y; Turker, Turker; Congologlu, Mehmet A; Sezigen, Sermet; Renklidag, Tulay; Karapirli, Mustafa; Javan, Gulnaz T

    2016-03-01

    Aggression, which is defined as a behavior causing harm or pain, is a behavioral pattern typically expected in children and adolescents who are involved in criminal activities. The aim of this study was to examine the relationship between aggression and self-injurious behavior (SIB) in children and adolescents. The study was performed in 295 cases which were sent for medicolegal examination. The mean age of the subjects was 14.27 ± 1.05 years (age range 10-18 years). The aggression levels of the subjects were determined using the Aggression Questionnaire (AQ), which is an updated form of the Buss-Durkee Hostility Inventory. The mean total AQ score of the subjects with and without SIB was 78.04 ± 21.0 and 62.75 ± 18.05, respectively (p aggression increased in children and adolescents who were involved in criminal activities when the SIBs increased. © 2016 American Academy of Forensic Sciences.

  18. Consumption of sucrose-sweetened soft drinks increases plasma levels of uric acid in overweight and obese subjects

    DEFF Research Database (Denmark)

    Bruun, J M; Maersk, M; Belza, A

    2015-01-01

    insulin resistance and low-grade inflammation, suggesting that UA may have a causal role in the development of metabolic complications. The objective of this study is to investigate the long-term effects of consuming SSSDs on circulating levels of UA in overweight and obese subjects. SUBJECTS...... milk, diet cola and water. Thus, a high daily intake of SSSDs in overweight and obese subjects without overt diabetes may increase the risk of developing metabolic complications through the elevation of UA. This trial is registered at ClinicalTrials.gov as NCT00777647.European Journal of Clinical......BACKGROUND/OBJECTIVES: Sucrose-sweetened soft drinks (SSSDs) are associated with the development of metabolic disorders. Fructose is a major component of SSSDs and is demonstrated to induce uric acid (UA) production and stimulate fat accumulation independent of excess caloric intake. UA induce...

  19. Lactobacillus gasseri SBT2055 reduces postprandial and fasting serum non-esterified fatty acid levels in Japanese hypertriacylglycerolemic subjects.

    Science.gov (United States)

    Ogawa, Akihiro; Kadooka, Yukio; Kato, Ken; Shirouchi, Bungo; Sato, Masao

    2014-02-19

    Lactobacillus gasseri SBT2055 (LG2055) inhibits dietary fat absorption in rats and exerts preventive effects on abdominal adiposity in rats and humans. The present study aimed to evaluate the effects of LG2055 on postprandial serum lipid responses in Japanese subjects with hypertriacylglycerolemia after the intake of oral fat-loading test (OFLT) meals. We conducted a single-blind, placebo-controlled, within-subject, repeated-measure intervention trial. Twenty subjects initially ingested the fermented milk (FM) without LG2055 for 4 weeks (control FM period), followed by a 4-week washout period, and then consumed FM containing LG2055 for 4 weeks (active FM period). The subjects were asked to consume FM at 200 g/day. At the end of each 4-week period, an 8-h OFLT was conducted. Blood samples were collected at fasting and every hour for 8 h after OFLT meal intake. Thereafter, postprandial serum non-esterified fatty acid (NEFA) and triacylglycerol (TAG) levels and fasting blood parameters were measured. The OFLT showed that the postprandial serum NEFA levels from 120 to 480 min and the postprandial serum TAG level at 120 min in the active FM period were significantly (P < 0.05) lower than those in the control FM period. The fasting serum NEFA level in the active FM period significantly (P < 0.001) decreased at week 4 from the initial period compared with the control FM period. The consumption of probiotic LG2055 reduced postprandial and fasting serum NEFA levels, suggesting its possible contribution to the reduction of the risk for obesity and type 2 diabetes mellitus. UMIN000011605.

  20. How Do Adolescents Increase Their Subjective Well-Being Level by Means of Relationships With Their Environment?

    Directory of Open Access Journals (Sweden)

    Ali Eryilmaz

    2012-08-01

    Full Text Available Purpose: In this study, investigating of how adolescents increase their subjective well-being level by means of relationships with their environment is aimed. Method: This study is carried out following the scanning model. The primarily participants of the study include a total of 360 adolescents (202 male and 158 female. The ages of them range between 14 and 17. Main study group include a total of 90 adolescents (45 male and 45 female. The data of the study were obtained through the use of the Adolescents’ Subjective Well-Being Increasing Scale and open ended questions. The data were analyzed through using of content analysis method with respect to sentences. Results: The findings obtained indicate that adolescents increase their subjective well-being levels with receiving positive reaction from an environment by means of such sub-strategies to get responses to the environment to be considered important and valuable, to receive social support, to receive responses which protect trust in relationships, to receive responses which increase perceived control, to receive responses which support the autonomy, to receive responses which increase the subjective well-being directly, and also to receive responses to be liked, to be understood, to be loved. In addition to these, adolescents increase their subjective well-being levels with reacting positively to an environment by means of such sub-strategies to show behaviors which increase the subjective well-being directly, to give social support, to establish positive relationship, to control yourself in relationship, to give a gift, to behave altruistically, to have optimistic taught, to give responses which protect trust in relationships, and also to pay compliments. Discussion and Conclusions: The findings of the study suggest that there are nine factors for reacting positively to an environment and also receiving positive reaction from an environment. Results of this study may be used for

  1. CO2 sequestration in two mediterranean dune areas subjected to a different level of anthropogenic disturbance

    Science.gov (United States)

    Bonito, Andrea; Ricotta, Carlo; Iberite, Mauro; Gratani, Loretta; Varone, Laura

    2017-09-01

    Coastal sand dunes are among the most threatened habitats, especially in the Mediterranean Basin, where the high levels of human pressure impair the presence of plant species, putting at risk the maintenance of the ecosystem services, such as CO2 sequestration provided by these habitats. The aim of this study was to analyze how disturbance-induced changes in plant species abundance patterns account for variations in annual CO2 sequestration flow (CS) of Mediterranean sand dune areas. Two sites characterized by a high (site HAD) and a lower (site LAD) anthropogenic disturbance level were selected. At both sites, plant species number, cover, height and CS based on net photosynthesis measurements were sampled. At the plant species level, our results highlighted that Ammophila arenaria and Pancratium maritimum, had a key role in CS. Moreover, the results revealed a patchy species assemblage in both sites. In particular, HAD was characterized by a higher extension of the anthropogenic aphytoic zone (64% of the total transect length) than LAD. In spite of the observed differences in plant species composition, there were not significant differences between HAD and LAD in structural and functional traits, such as plant height and net photosynthesis. As a consequence, HAD and LAD had a similar CS (443 and 421 Mg CO2 ha-1 y-1, respectively). From a monetary point of view, our estimates based on the social costs of carbon revealed that the flow of sequestered CO2 valued on an average 3181 ± 114 ha-1 year-1 (mean value for the two sites). However, considering also the value of the CO2 negative flow related to loss of vegetated area, the annual net benefit arising from CO2 sequestration amounted to 1641 and 1772 for HAD and LAD, respectively. Overall, the results highlighted the importance to maximize the efforts to preserve dune habitats by applying an effective management policy, which could allow maintaining also a regulatory ecosystem service such as CO2 sequestration.

  2. Association of Parkinson's disease with altered serum levels of lead and transition metals among South Indian subjects.

    Science.gov (United States)

    Kumudini, Nadella; Uma, Addepally; Devi, Yalavarthy Prameela; Naushad, Shaik Mohammad; Mridula, Rukmini; Borgohain, Rupam; Kutala, Vijay Kumar

    2014-04-01

    Several epidemiologic studies have suggested an association between the Parkinson's disease (PD) and exposure to heavy metals, such as lead, iron, copper, manganese, etc. A growing body of evidence suggests that heavy metals stimulate free radical formation in the brain and can lead to neurodegeneration. In the present study, we investigated whether such association exists in PD cases from rural and urban areas in our study population. The plasma levels of copper, iron, manganese and lead in PD cases (n = 150) and controls (n = 170) were determined by inductively coupled plasma mass spectrometry (ICP-MS) and correlated with the oxidative stress markers like malondialdehyde (MDA), protein carbonyl and total glutathione. Results indicated significant increase in the levels of copper (17.73 +/- 4.48 vs. 13.0 + 3.22 ng/ml) and iron (554.4 +/- 123.8 vs. 421.7 +/- 126.1 ng/ml) in PD cases compared to controls, whereas no significant differences in the levels of manganese and lead were observed. Further, the data based on urban or rural residence showed that plasma copper, iron, manganese levels were comparatively higher in rural subjects, whereas plasma lead levels were significantly higher in urban subjects. Increased plasma iron showed positive correlation with marker of lipid peroxidation (MDA), suggesting that increased iron levels induced oxidative stress in PD. These results substantiated the earlier observations about the role of environmental exposure and metal-induced oxidative stress in the etiology of PD.

  3. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory

    Science.gov (United States)

    Lawton, Teri; Shelley-Tremblay, John

    2017-01-01

    The purpose of this study was to determine whether neurotraining to discriminate a moving test pattern relative to a stationary background, figure-ground discrimination, improves vision and cognitive functioning in dyslexics, as well as typically-developing normal students. We predict that improving the speed and sensitivity of figure-ground movement discrimination (PATH to Reading neurotraining) acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed, reading fluency, and the executive control functions of attention and working memory in both dyslexic and normal students who had PATH neurotraining more than in those students who had no neurotraining. This prediction was evaluated by measuring whether dyslexic and normal students improved on standardized tests of cognitive skills following neurotraining exercises, more than following computer-based guided reading (Raz-Kids (RK)). The neurotraining used in this study was visually-based training designed to improve magnocellular function at both low and high levels in the dorsal stream: the input to the executive control networks coding working memory and attention. This approach represents a paradigm shift from the phonologically-based treatment for dyslexia, which concentrates on high-level speech and reading areas. This randomized controlled-validation study was conducted by training the entire second and third grade classrooms (42 students) for 30 min twice a week before guided reading. Standardized tests were administered at the beginning and end of 12-weeks of intervention training to evaluate improvements in academic skills. Only movement-discrimination training remediated both low-level visual timing deficits and high-level cognitive functioning, including selective and sustained attention, reading fluency and working memory for both dyslexic and normal students. Remediating visual timing deficits in the dorsal stream revealed the causal role of visual movement

  4. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory.

    Science.gov (United States)

    Lawton, Teri; Shelley-Tremblay, John

    2017-01-01

    The purpose of this study was to determine whether neurotraining to discriminate a moving test pattern relative to a stationary background, figure-ground discrimination, improves vision and cognitive functioning in dyslexics, as well as typically-developing normal students. We predict that improving the speed and sensitivity of figure-ground movement discrimination (PATH to Reading neurotraining) acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed, reading fluency, and the executive control functions of attention and working memory in both dyslexic and normal students who had PATH neurotraining more than in those students who had no neurotraining. This prediction was evaluated by measuring whether dyslexic and normal students improved on standardized tests of cognitive skills following neurotraining exercises, more than following computer-based guided reading (Raz-Kids (RK)). The neurotraining used in this study was visually-based training designed to improve magnocellular function at both low and high levels in the dorsal stream: the input to the executive control networks coding working memory and attention. This approach represents a paradigm shift from the phonologically-based treatment for dyslexia, which concentrates on high-level speech and reading areas. This randomized controlled-validation study was conducted by training the entire second and third grade classrooms (42 students) for 30 min twice a week before guided reading. Standardized tests were administered at the beginning and end of 12-weeks of intervention training to evaluate improvements in academic skills. Only movement-discrimination training remediated both low-level visual timing deficits and high-level cognitive functioning, including selective and sustained attention, reading fluency and working memory for both dyslexic and normal students. Remediating visual timing deficits in the dorsal stream revealed the causal role of visual movement

  5. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory

    Directory of Open Access Journals (Sweden)

    Teri Lawton

    2017-05-01

    Full Text Available The purpose of this study was to determine whether neurotraining to discriminate a moving test pattern relative to a stationary background, figure-ground discrimination, improves vision and cognitive functioning in dyslexics, as well as typically-developing normal students. We predict that improving the speed and sensitivity of figure-ground movement discrimination (PATH to Reading neurotraining acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed, reading fluency, and the executive control functions of attention and working memory in both dyslexic and normal students who had PATH neurotraining more than in those students who had no neurotraining. This prediction was evaluated by measuring whether dyslexic and normal students improved on standardized tests of cognitive skills following neurotraining exercises, more than following computer-based guided reading (Raz-Kids (RK. The neurotraining used in this study was visually-based training designed to improve magnocellular function at both low and high levels in the dorsal stream: the input to the executive control networks coding working memory and attention. This approach represents a paradigm shift from the phonologically-based treatment for dyslexia, which concentrates on high-level speech and reading areas. This randomized controlled-validation study was conducted by training the entire second and third grade classrooms (42 students for 30 min twice a week before guided reading. Standardized tests were administered at the beginning and end of 12-weeks of intervention training to evaluate improvements in academic skills. Only movement-discrimination training remediated both low-level visual timing deficits and high-level cognitive functioning, including selective and sustained attention, reading fluency and working memory for both dyslexic and normal students. Remediating visual timing deficits in the dorsal stream revealed the causal role of visual

  6. Contributions of morphological awareness skills to word-level reading and spelling in first-grade children with and without speech sound disorder.

    Science.gov (United States)

    Apel, Kenn; Lawrence, Jessika

    2011-10-01

    In this study, the authors compared the morphological awareness abilities of children with speech sound disorder (SSD) and children with typical speech skills and examined how morphological awareness ability predicted word-level reading and spelling performance above other known contributors to literacy development. Eighty-eight first-grade students--44 students with SSD and no known history of language deficiencies, and 44 students with typical speech and language skills--completed an assessment battery designed to measure speech sound production, morphological awareness, phonemic awareness, letter-name knowledge, receptive vocabulary, word-level reading, and spelling abilities. The children with SSD scored significantly lower than did their counterparts on the morphological awareness measures as well as on phonemic awareness, word-level reading, and spelling tasks. Regression analyses suggested that morphological awareness predicted significant unique variance on the spelling measure for both groups and on the word-level reading measure for the children with typical skills. These results suggest that children with SSD may present with a general linguistic awareness insufficiency, which puts them at risk for difficulties with literacy and literacy-related tasks.

  7. Levels of Reading Comprehension across Text Types: A Comparison of Literal and Inferential Comprehension of Expository and Narrative Texts in Iranian EFL Learners

    Science.gov (United States)

    Saadatnia, Mahmood; Ketabi, Saeed; Tavakoli, Mansoor

    2017-01-01

    The purpose of this study was to investigate two levels of reading comprehension, namely literal and inferential, of two text types of narration and exposition in Iranian EFL learners. The elicitation instruments were four expository texts and four narrative ones. One hundred eighty upper-intermediate EFL learners were assigned the reading…

  8. Braille Reading Accuracy of Students Who Are Visually Impaired: The Effects of Gender, Age at Vision Loss, and Level of Education

    Science.gov (United States)

    Argyropoulos, Vassilis; Papadimitriou, Vassilios

    2015-01-01

    Introduction: The present study assesses the performance of students who are visually impaired (that is, those who are blind or have low vision) in braille reading accuracy and examines potential correlations among the error categories on the basis of gender, age at loss of vision, and level of education. Methods: Twenty-one visually impaired…

  9. The Effects of Computer-Assisted Instruction Based on Top-Level Structure Method in English Reading and Writing Abilities of Thai EFL Students

    Science.gov (United States)

    Jinajai, Nattapong; Rattanavich, Saowalak

    2015-01-01

    This research aims to study the development of ninth grade students' reading and writing abilities and interests in learning English taught through computer-assisted instruction (CAI) based on the top-level structure (TLS) method. An experimental group time series design was used, and the data was analyzed by multivariate analysis of variance…

  10. Contributions of Morphological Awareness Skills to Word-Level Reading and Spelling in First-Grade Children with and without Speech Sound Disorder

    Science.gov (United States)

    Apel, Kenn; Lawrence, Jessika

    2011-01-01

    Purpose: In this study, the authors compared the morphological awareness abilities of children with speech sound disorder (SSD) and children with typical speech skills and examined how morphological awareness ability predicted word-level reading and spelling performance above other known contributors to literacy development. Method: Eighty-eight…

  11. Effects of the Helping Early Literacy with Practice Strategies (HELPS) on Reading Fluency with Secondary Level Students Attending an Alternative Education Program

    Science.gov (United States)

    Breault, Holly

    2017-01-01

    The purpose of this study was to investigate the effect of the HELPS Program on the reading fluency skills of secondary level students attending an alternative education program using single case design methodology. Participants in this study included one 8th grade student and two 9th grade students attending an alternative education program in…

  12. Risk Analysis of a Two-Level Supply Chain Subject to Misplaced Inventory

    Directory of Open Access Journals (Sweden)

    Lijing Zhu

    2017-06-01

    Full Text Available Misplaced inventory is prevalent in retail stores and may lead to the overall poor performance of the supply chain. We explore the impact of misplaced inventory on a two-level supply chain, which consists of a risk-neutral supplier and a risk-averse retailer. The supplier decides the wholesale price to maximize her profit, whereas the retailer decides the order quantity to maximize his utility. Under the Conditional Value-at-Risk (CVaR criterion, we formulate the problem as a Stackelberg game model and obtain the equilibrium solutions in three cases: (i information asymmetry about inventory errors exists; (ii the retailer shares information about inventory errors with the supplier; and (iii in order to reduce misplaced inventory, the supply chain deploys Radio-Frequency Identification (RFID technology. The benefits of information sharing and RFID implementation are explored. A revenue and cost sharing contract is proposed to coordinate the supply chain and to allocate the cost savings from RFID implementation among supply chain participants. Finally, we provide managerial insights for risk-averse decision makers that are considering investing in the RFID technology.

  13. Calcium and magnesium uptake by oat cultivars subjected to aluminum toxicity levels

    Directory of Open Access Journals (Sweden)

    José Antonio Gonzalez da Silva

    2013-12-01

    Full Text Available Acid soils with high aluminum (Al concentrations affect the productivity of oats and many crops. The toxicity of this cation, besides reducing root growth, interferes on the uptake, transport and use of nutrients such as magnesium (Mg and calcium (Ca. The objective of this work was to evaluate the Ca and Mg uptake ability by measuring their content in the leaf tissues of white oat cultivars. Tolerant and sensitive cultivars were tested under hydroponic culture to verify if the genotypes with greater uptake ability of Ca and Mg do represent those with a tolerant response. In the study, two experiments were performed, one to validate the tolerance groups based on root regrowth and another aiming to reach plant dry masses large enough to determine Ca and Mg. In both situations, the experimental design was completely random at a 3 x 6 factorial for dose and genotype with three replications. The uptake of Ca and Mg are affected by the addition of Al to the hydroponic solution, with tolerant cultivars showing higher concentrations on the leaf tissues than sensitive ones in the absence and presence of Al. Therefore, there is a link between the tolerance levels with the Al uptake, representing a variable to be employed on the selection of more efficient genotypes.

  14. Medical students' subjective ratings of stress levels and awareness of student support services about mental health.

    Science.gov (United States)

    Walter, Garry; Soh, Nerissa Li-Wey; Norgren Jaconelli, Sanna; Lampe, Lisa; Malhi, Gin S; Hunt, Glenn

    2013-06-01

    To descriptively assess medical students' concerns for their mental and emotional state, perceived need to conceal mental problems, perceived level of support at university, knowledge and use of student support services, and experience of stresses of daily life. From March to September 2011, medical students at an Australian university were invited to complete an anonymous online survey. 475 responses were received. Students rated study and examinations (48.9%), financial concerns (38.1%), isolation (19.4%) and relationship concerns (19.2%) as very or extremely stressful issues. Knowledge of available support services was high, with 90.8% indicating they were aware of the university's medical centre. Treatment rates were modest (31.7%). Students' concerns about their mental state were generally low, but one in five strongly felt they needed to conceal their emotional problems. Despite widespread awareness of appropriate support services, a large proportion of students felt they needed to conceal mental and emotional problems. Overall treatment rates for students who were greatly concerned about their mental and emotional state appeared modest, and, although comparable with those of similarly aged community populations, may reflect undertreatment. It would be appropriate for universities to address stressors identified by students. Strategies for encouraging distressed students to obtain appropriate assessment and treatment should also be explored. Those students who do seek healthcare are most likely to see a primary care physician, suggesting an important screening role for these health professionals.

  15. Reading, but Not Reading Well--Reading Skills at Level 3. A Report from the Survey of Literacy Skills Used in Daily Activities = Capables de Lire, mais pas Tres Bien--Les Lectueurs de Niveau 3. Un rapport de l'enquete sur les capacites de lecture et d'ecriture utilisees quotidiennement.

    Science.gov (United States)

    Jones, Stan

    Research on adult literacy in Canada showed the need for another category of adult reader--Level 3. Canadians at Level 3 can use reading materials in a variety of situations, provided the material is simple and clearly laid out, and the tasks involved are not too complicated. Although these people generally do not see themselves as having…

  16. The effectiveness of audio books on the reading comprehension of selected texts by university EFL students at different proficiency levels

    OpenAIRE

    Türker, Sami

    2010-01-01

    Ankara : The Department of Teaching English as a Foreign Language, Bilkent University, 2010. Thesis (Master's) -- Bilkent University, 2010. Includes bibliographical references leaves 79-83. This study mainly investigated the effectiveness of audio books on the reading comprehension of selected texts by university EFL students. This study also aimed to find out whether a difference in students‘ reading comprehension as a result of exposure to audio books emerges based on thei...

  17. Energy utilization of light and heavy weaned piglets subjected to different dietary energy levels

    Directory of Open Access Journals (Sweden)

    Andréa Machado Leal Ribeiro

    Full Text Available ABSTRACT This study was conducted to evaluate the effects of dietary metabolisable energy (ME: 3.25, 3.40, 3.55, or 3.70 Mcal kg−1 and weaning weight (WW: light 4.0±0.7 kg, and heavy: 6.3±0.6 kg on productive response and energy utilization of weaned piglets. Sixty-four male piglets were housed in 32 metabolic cages (two animals per cage during the first 14 d postweaning. At day 15, only one animal per cage was kept until day 28. Body composition, energy, and nutrient deposition rates and energy utilization efficiency were measured through a comparative slaughter procedure. Piglets with light WW had a poorer feed conversion ratio and lower weight gain and feed intake when expressed per live weight. Increased ME led to greater daily fat deposition in the empty bodies (defined as weighted mean of the carcass + organs + blood, no intestinal content, while light WW piglets had a reduced protein deposition. Light WW piglets increased heat production with increased ME, but no effect was seen for the heavy WW piglets. By contrast, heavy WW piglets increased empty body gross energy as ME increased, while no influence was observed on light WW piglets. Increasing dietary energy levels did not contribute to the subsequent growth performance of piglets that were lighter at weaning. The lack of interaction between weaning weight and dietary ME content on growth performance does not support the hypothesis that light piglets at weaning do not exhibit compensatory growth because of limitations in energy intake.

  18. A Special Chinese Reading Acceleration Training Paradigm: To Enhance the Reading Fluency and Comprehension of Chinese Children with Reading Disabilities

    Directory of Open Access Journals (Sweden)

    Li Dai

    2016-12-01

    Full Text Available According to a number of studies, use of a Reading Acceleration Program as reading intervention training has been demonstrated to improve reading speed and comprehension level effectively in most languages and countries. The objective of the current study was to provide further evidence of the effectiveness of a Reading Acceleration Program for Chinese children with reading disabilities using a distinctive Chinese reading acceleration training paradigm. The reading acceleration training paradigm is divided into a non-accelerated reading paradigm, a Character-accelerated reading paradigm and a Words-accelerated reading paradigm. The results of training Chinese children with reading disabilities indicate that the acceleration reading paradigm applies to children with Chinese-reading disabilities. In addition, compared with other reading acceleration paradigms, Words- accelerated reading training is more effective in helping children with reading disabilities read at a high speed while maintaining superior comprehension levels.

  19. Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.

    Directory of Open Access Journals (Sweden)

    Xiaobo Yang

    2012-09-01

    Full Text Available Complement C3 and C4 play key roles in the main physiological activities of complement system, and their deficiencies or over-expression are associated with many clinical infectious or immunity diseases. A two-stage genome-wide association study (GWAS was performed for serum levels of C3 and C4. The first stage was conducted in 1,999 healthy Chinese men, and the second stage was performed in an additional 1,496 subjects. We identified two SNPs, rs3753394 in CFH gene and rs3745567 in C3 gene, that are significantly associated with serum C3 levels at a genome-wide significance level (P = 7.33 × 10(-11 and P = 1.83 × 10(-9, respectively. For C4, one large genomic region on chromosome 6p21.3 is significantly associated with serum C4 levels. Two SNPs (rs1052693 and rs11575839 were located in the MHC class I area that include HLA-A, HLA-C, and HLA-B genes. Two SNPs (rs2075799 and rs2857009 were located 5' and 3' of C4 gene. The other four SNPs, rs2071278, rs3763317, rs9276606, and rs241428, were located in the MHC class II region that includes HLA-DRA, HLA-DRB, and HLA-DQB genes. The combined P-values for those eight SNPs ranged from 3.19 × 10(-22 to 5.62 × 10(-97. HBsAg-positive subjects have significantly lower C3 and C4 protein concentrations compared with HBsAg-negative subjects (P<0.05. Our study is the first GWAS report which shows genetic components influence the levels of complement C3 and C4. Our significant findings provide novel insights of their related autoimmune, infectious diseases, and molecular mechanisms.

  20. Reading and the Slow Learner.

    Science.gov (United States)

    Ediger, Marlow

    Advocates of high standards and expectations usually believe that gaps in reading achievement can be eliminated with good teaching, but slow readers need a specially designed reading curriculum. The teacher first needs to use an informal reading inventory to determine the student's reading level. Functioning generally on a higher level than…

  1. Impact of layover length on sleep, subjective fatigue levels, and sustained attention of long-haul airline pilots.

    Science.gov (United States)

    Roach, Gregory D; Petrilli, Renée M A; Dawson, Drew; Lamond, Nicole

    2012-06-01

    Long-haul airline pilots often experience elevated levels of fatigue due to extended work hours and circadian misalignment of sleep and wake periods. During long-haul trips, pilots are typically given 1-3 d off between flights (i.e., layover) to recover from, and prepare for, duty. Anecdotally, some pilots prefer long layovers because it maximizes the time available for recovery and preparation, but others prefer short layovers because it minimizes both the length of the trip, and the degree to which the body clock changes from "home time" to the layover time zone. The aim of this study was to examine the impact of layover length on the sleep, subjective fatigue levels, and capacity to sustain attention of long-haul pilots. Participants were 19 male pilots (10 Captains, 9 First Officers) working for an international airline. Data were collected during an 11- or 12-d international trip. The trips involved (i) 4 d at home prior to the trip; (ii) an eastward flight of 13.5 h across seven time zones; (iii) a layover of either 39 h (i.e., short, n = 9) or 62 h (i.e., long, n = 10); (iv) a return westward flight of 14.3 h across seven time zones; and (v) 4 d off at home after the trip. Sleep was recorded using a self-report sleep diary and wrist activity monitor; subjective fatigue level was measured using the Samn-Perelli Fatigue Checklist; and sustained attention was assessed using the psychomotor vigilance task for a personal digital assistant (PalmPVT). Mixed-model regression analyses were used to determine the effects of layover length (short, long) on the amount of sleep that pilots obtained during the trip, and on the pilots' subjective fatigue levels and capacity to sustain attention. There was no main effect of layover length on ground-based sleep or in-flight sleep, but pilots who had a short layover at the midpoint of their trip had higher subjective fatigue levels and poorer sustained attention than pilots who had a long layover. The results of this study

  2. Lipoprotein-Associated Phospholipase A2 Mass Level Is Increased in Elderly Subjects with Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    J. Fortunato

    2014-01-01

    Full Text Available Objective. Lipoprotein-associated phospholipase A2 (Lp-PLA2 is extensively expressed by advanced atherosclerotic lesions and may play a role in plaque instability. We selected a group of elderly subjects that underwent transcatheter aortic valve implantation (TAVI or balloon angioplasty (BA and separated them into two groups, diabetic and nondiabetic, to compare the level of Lp-PLA2 mass between them. Methods. 44 patients aged 79.6±5.6 years with symptomatic severe aortic valve stenosis underwent TAVI (n=35 or BA (n=9. 21 subjects had confirmed type 2 diabetes mellitus. Lp-PLA2 mass was measured using an enzyme-linked immunosorbent assay kit (USCN Life Science, China before and 3 days after the procedure. Results. Lp-PLA2 mass was significantly elevated in this population (1296±358 ng/mL before TAVI; 1413±268 ng/mL before BA and further increased after TAVI (1604±437 ng/mL, P<0.01 or BA (1808±303 ng/mL, P<0.01. Lp-PLA2 mass was significantly increased on the diabetic group before these interventions. Conclusion. Lp-PLA2 may be a novel biomarker for the presence of rupture-prone atherosclerotic lesions in elderly patients. Levels of Lp-PLA2 in diabetic patients may accompany the higher amount of small dense LDL particles seen in these subjects.

  3. Haemoglobin F, A2, and S levels in subjects with or without sickle cell trait in south-eastern Gabon.

    Science.gov (United States)

    Mombo, Landry-Erik; Mabioko-Mbembo, Gaël; Kassa-Kassa, Roland-Fabrice; Ontsitsagui, Emmanuel; Mboui-Ondo, Statiana; Nzé-Kamsi, Leatitia; Nkoghé, Dieudonné; Elion, Jacques

    2017-09-01

    Infant mortality due to sickle cell disease in sub-Saharan Africa is high, necessitating a better understanding of the modulating factors of the disease in this region. We assessed the hereditary persistence of foetal haemoglobin and α-thalassemia. We diagnosed 787 subjects, with or without sickle cell trait, by capillary electrophoresis in the Medical Diagnostic Laboratory of the CIRMF (Franceville, Gabon). Heterocellular and pancellular forms of hereditary persistence of foetal haemoglobin occurred at low rates of 10.9 and 2.3%, respectively. The distribution of HbS levels in individuals with sickle cell trait was trimodal, showing a high percentage (52.4%) of heterozygous subjects with α-thalassemia. The distribution of HbA2 levels was bimodal in individuals without sickle cell trait, estimated to be comprised of 12 and 15% of α and β-thalassemic heterozygous subjects, respectively. In sub-Saharan Africa, α-thalassemia is a far more prevalent modulating factor than hereditary persistence of foetal haemoglobin. Our study highlights the need for further investigation of thalassemia, haemoglobinopathies that are neglected in sub-Saharan Africa.

  4. Neural activations correlated with reading speed during reading novels.

    Science.gov (United States)

    Fujimaki, Norio; Munetsuna, Shinji; Sasaki, Toyofumi; Hayakawa, Tomoe; Ihara, Aya; Wei, Qiang; Terazono, Yasushi; Murata, Tsutomu

    2009-12-01

    Functional magnetic resonance imaging was used to measure neural activations in subjects instructed to silently read novels at ordinary and rapid speeds. Among the 19 subjects, 8 were experts in a rapid reading technique. Subjects pressed a button to turn pages during reading, and the interval between turning pages was recorded to evaluate the reading speed. For each subject, we evaluated activations in 14 areas and at 2 instructed reading speeds. Neural activations decreased with increasing reading speed in the left middle and posterior superior temporal area, left inferior frontal area, left precentral area, and the anterior temporal areas of both hemispheres, which have been reported to be active for linguistic processes, while neural activation increased with increasing reading speed in the right intraparietal sulcus, which is considered to reflect visuo-spatial processes. Despite the considerable reading speed differences, correlation analysis showed no significant difference in activation dependence on reading speed with respect to the subject groups and instructed reading speeds. The activation reduction with speed increase in language-related areas was opposite to the previous reports for low reading speeds. The present results suggest that subjects reduced linguistic processes with reading speed increase from ordinary to rapid speed.

  5. Cuff pressure pain detection is associated with both sex and physical activity level in nonathletic healthy subjects

    DEFF Research Database (Denmark)

    Lemming, Dag; Börsbo, Björn; Sjörs, Anna

    2017-01-01

    analogue scale (VAS). The pain detection threshold (PDT) was defined as when the pressure was perceived as painful, and pain tolerance (PTT) was when the subject terminated the cuff inflation. For PTT, the corresponding VAS score was recorded (VAS-PTT). The protocol was repeated with two chambers inflated......PURPOSE : The aim of this study was to evaluate pressure pain sensitivity on leg and arm in 98 healthy persons (50 women) using cuff algometry. Furthermore, associations with sex and physical activity level were investigated. METHOD:  Normal physical activity level was defined as Godin Leisure......-Time Exercise Questionnaire (GLTEQ) score ≤ 45 and high activity level as GLTEQ > 45. A pneumatic double-chamber cuff was placed around the arm or leg where a single chamber was inflated. The cuff inflation rate (1 kPa/s) was constant, and pain intensity was registered continuously on a 10 cm electronic visual...

  6. Plasma hormone levels in human subject during stress loads in microgravity and at readaptation to Earth's gravity.

    Science.gov (United States)

    Macho, L; Koska, J; Ksinantova, L; Vigas, M; Noskov, V B; Grigoriev, A I; Kvetnansky, R

    2001-07-01

    In great part of the investigations of endocrine system functions in astronauts during space flights the plasma levels of hormones and metabolites were determined only in resting conditions, usually from one blood sample collection. Such levels reflected the psychical and physical state and new hormonal homeostasis of organism at the time of blood collection, however, the functional capacity of neuroendocrine system to respond to various stress stimuli during space flight remained unknown. The aim of present investigations was to study dynamic changes of hormone levels during the stress and metabolic loads (insulin induced hypoglycemia, physical exercise and oral glucose tolerance test) at the exposure of human subject to microgravity on the space station MIR. The responses of sympatico-adrenomedullary system to these stress and workloads were presented by Kvetnansky et al.

  7. Comparison of fractional exhaled nitric oxide levels in chronic obstructive pulmonary disease, bronchial asthma and healthy subjects of Nepal.

    Science.gov (United States)

    Shrestha, Sanjeet Krishna; Shrestha, Sanjeev; Sharma, Lucky; Pant, Subash; Neopane, Arpana

    2017-09-13

    Fractional exhaled nitric oxide levels in exhaled breath can indicate ongoing eosinophilic airway inflammation, specifically in asthma. But its utility is being explored for central airway inflammations, including chronic obstructive pulmonary disease. Normal levels of fractional exhaled nitric oxide (FENO50) have been defined in different studies but not in Nepal. This study compares FENO50 levels in normal subjects, asthma and chronic obstructive pulmonary disease. Single breath estimation of FENO50 was measured by a handheld electrochemical sensor-based device in normal non-smoking adults (n = 106), clinically controlled asthma (n = 106) and stable chronic obstructive pulmonary disease (n = 106). The geometric mean for FENO50 was 14 parts per billion (ppb) with a median of 16 ppb, first quartile at 11 ppb and third quartile at 20 ppb in normal non-smoking adults. The values were 31 ppb (geometric mean), 34 ppb (median), 17 ppb (first quartile) and 79 ppb (third quartile) in clinically controlled asthma. Similarly the values were 10 ppb (geometric mean), 11 ppb (median), 6 ppb (first quartile) and 17 ppb (third quartile) in stable chronic obstructive airway disease. The log-transformed data showed significantly higher FENO50 levels in the asthma group compared with the normal (p chronic obstructive airway disease (p chronic obstructive airway disease groups (p = 0.08). FENO50 levels were higher in bronchial asthma (despite disease control) than in normal non-smoking adults and subjects with stable chronic obstructive pulmonary disease. Levels of FENO50 were similar between the chronic obstructive airway disease and normal groups.

  8. Glycoprotein YKL-40 Levels in Plasma Are Associated with Fibrotic Changes on HRCT in Asbestos-Exposed Subjects

    Directory of Open Access Journals (Sweden)

    Tuija Väänänen

    2017-01-01

    Full Text Available YKL-40 is a chitinase-like glycoprotein produced by alternatively activated macrophages that are associated with wound healing and fibrosis. Asbestosis is a chronic asbestos-induced lung disease, in which injury of epithelial cells and activation of alveolar macrophages lead to enhanced collagen production and fibrosis. We studied if YKL-40 is related to inflammation, fibrosis, and/or lung function in subjects exposed to asbestosis. Venous blood samples were collected from 85 men with moderate or heavy occupational asbestos exposure and from 28 healthy, age-matched controls. Levels of plasma YKL-40, CRP, IL-6, adipsin, and MMP-9 were measured with enzyme-linked immunosorbent assay (ELISA. Plasma YKL-40 levels were significantly higher in subjects with asbestosis (n=19 than in those with no fibrotic findings in HRCT following asbestos exposure (n=66 or in unexposed healthy controls. In asbestos-exposed subjects, plasma YKL-40 correlated negatively with lung function capacity parameters FVC (Pearson’s r −0.259, p=0.018 and FEV1 (Pearson’s r −0.240, p=0.028 and positively with CRP (Spearman’s rho 0.371, p<0.001, IL-6 (Spearman’s rho 0.314, p=0.003, adipsin (Spearman’s rho 0.459, p<0.001, and MMP-9 (Spearman’s rho 0.243, p=0.025. The present finding suggests YKL-40 as a biomarker associated with fibrosis and inflammation in asbestos-exposed subjects.

  9. Individual cortical connectivity changes after stroke: a resampling approach to enable statistical assessment at single-subject level.

    Science.gov (United States)

    Petti, M; Pichiorri, F; Toppi, J; Cincotti, F; Salinari, S; Babiloni, F; Mattia, D; Astolfi, L

    2014-01-01

    One of the main limitations commonly encountered when dealing with the estimation of brain connectivity is the difficulty to perform a statistical assessment of significant changes in brain networks at a single-subject level. This is mainly due to the lack of information about the distribution of the connectivity estimators at different conditions. While group analysis is commonly adopted to perform a statistical comparison between conditions, it may impose major limitations when dealing with the heterogeneity expressed by a given clinical condition in patients. This holds true particularly for stroke when seeking for quantitative measurements of the efficacy of any rehabilitative intervention promoting recovery of function. The need is then evident of an assessment which may account for individual pathological network configuration associated with different level of patients' response to treatment; such network configuration is highly related to the effect that a given brain lesion has on neural networks. In this study we propose a resampling-based approach to the assessment of statistically significant changes in cortical connectivity networks at a single subject level. First, we provide the results of a simulation study testing the performances of the proposed approach under different conditions. Then, to show the sensitivity of the method, we describe its application to electroencephalographic (EEG) data recorded from two post-stroke patients who showed different clinical recovery after a rehabilitative intervention.

  10. Influence of food restriction on lipid profile and spontaneous glucose levels in male rats subjected to paradoxical sleep deprivation

    Directory of Open Access Journals (Sweden)

    Tathiana Aparecida Alvarenga

    2012-01-01

    Full Text Available OBJECTIVES: The purpose of this study was to determine the paired consequences of food restriction and paradoxical sleep deprivation on lipid profile and spontaneous glucose levels in male rats. METHOD: Food restriction began at weaning, with 6 g of food being provided per day, which was subsequently increased by 1 g per week until reaching 15 g per day by the eighth week. At adulthood, both rats subjected to food restriction and those fed ad libitum were exposed to paradoxical sleep deprivation for 96 h or were maintained in their home-cage groups. RESULTS: Animals subjected to food restriction exhibited a significant increase in high-density lipoprotein levels compared to animals that were given free access to food. After the paradoxical sleep deprivation period, the foodrestricted animals demonstrated reduced concentrations of high-density lipoprotein relative to their respective controls, although the values for the food-restricted animals after sleep deprivation were still higher than those for the ad libitum group. The concentration of low-density lipoproteins was significantly increased in sleep-deprived animals fed the ad libitum diet. The levels of triglycerides, very low-density lipoproteins, and glucose in foodrestricted animals were each decreased compared to both ad libitum groups. CONCLUSION: These results may help to illustrate the mechanisms underlying the relationship between sleep curtailment and metabolism and may suggest that, regardless of sleep deprivation, dietary restriction can minimize alterations in parameters related to cardiovascular risk.

  11. Relationship between the Finnish Diabetes Risk Score (FINDRISC), vitamin D levels, and insulin resistance in obese subjects.

    Science.gov (United States)

    Lima-Martínez, Marcos M; Arrau, Carlos; Jerez, Saimar; Paoli, Mariela; González-Rivas, Juan P; Nieto-Martínez, Ramfis; Iacobellis, Gianluca

    2017-02-01

    To assess the relationship between 25-hydroxyvitamin D [25(OH)D] blood concentrations in subjects with obesity and type 2 diabetes mellitus (T2D) risk according to the Finnish Diabetes Risk Score (FINDRISC) modified for Latin America (LA-FINDRISC). This study was conducted in Ciudad Bolívar, Venezuela. Eighty two women and 20 men (53 obese and 49 nonobese), with an average age of 42.6±12.30 years were enrolled. Weight, height, body mass index (BMI), waist circumference (WC), fasting glucose, basal insulin, plasma lipids, Homeostasis Model Assessment-Insulin Resistance (HOMA-IR), and 25(OH)D levels were measured. FINDRISC with WC cutoff points modified for Latin America was applied. No difference in 25(OH)D levels between obese and nonobese subjects was found. When anthropometric, clinical, and biochemical variables according to the 25(OH)D status were compared, the only difference detected was higher LA-FINDRISC in the insufficient/low 25(OH)D group compared to normal 25(OH)D levels group (12.75±6.62; vs 10.15±5.21; p=0.031). LA-FINDRISC was negatively correlated with plasma 25(OH)D levels (r=-0.302; p=0.002) and positively correlated with the HOMA-IR index (r=0.637; p=0.0001). The LA-FINDRISC significantly correlated with both 25(OH)D levels and insulin resistance markers in this group of patients. Copyright © 2016 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

  12. How Knowledge Powers Reading

    Science.gov (United States)

    Lemov, Doug

    2017-01-01

    Recent research shows that reading comprehension relies heavily on prior knowledge. Far more than generic "reading skills" like drawing inferences, making predictions, and knowing the function of subheads, how well students learn from a nonfiction text depends on their background knowledge of the text's subject matter. And in a cyclical…

  13. Comparison of salivary epidermal growth factor levels in patients with gingivitis and advanced periodontitis and healthy subjects.

    Directory of Open Access Journals (Sweden)

    Mahvash Moosavijazi

    2014-10-01

    Full Text Available Epidermal growth factor (EGF is a polypeptide molecule, with important functions in epithelial growth and wound repair. It exerts its effects on cells by binding to receptors on the cell surface. The aim of this study was to evaluate and compare salivary EGF levels in patients with gingivitis and advanced periodontitis as well as in healthy controls.Unstimulated salivary samples were collected from patients with gingivitis and advanced periodontitis and healthy individuals. The clinical parameters of plaque index (PI, bleeding on probing (BOP, probing pocket depth (PPD and clinical attachment level (CAL were measured and recorded using a Williams probe. The enzyme-linked immunosorbent assay (ELISA was used to determine salivary levels of EGF. One-way ANOVA was used for data analysis.The mean salivary level of EGF in healthy individuals (99.27 was significantly higher than that in patients with gingivitis (61.53. This value in patients with gingivitis (61.53 was also significantly higher than that in subjects with periodontitis (36.14 (P<0.001.The reduction in salivary level of EGF in patients with periodontal disease may be related to the pathogenesis of periodontitis.

  14. Effects of itopride hydrochloride on plasma gut-regulatory peptide and stress-related hormone levels in healthy human subjects.

    Science.gov (United States)

    Katagiri, Fumihiko; Shiga, Toru; Inoue, Shin; Sato, Yuhki; Itoh, Hiroki; Takeyama, Masaharu

    2006-01-01

    Itopride hydrochloride (itopride), a gastrokinetic drug, has recently been evaluated for its clinical usefulness in functional dyspepsia. We investigated effects of itopride on human plasma gastrin-, somatostatin-, motilin-, and cholecystokinin (CCK)-like immunoreactive substances (IS); adrenocorticotropic hormone (ACTH)-immunoreactive substances (IS), and cortisol under stress conditions in healthy subjects. A single administration of itopride caused significant increases in plasma somatostatin- and motilin-IS levels compared to placebo. Itopride significantly decreased plasma CCK-IS, and suppressed the ACTH-IS level compared to placebo. We hypothesize that itopride may have an accelerating gastric emptying effect, and a modulatory effect on the hypothalamo-pituitary-adrenal axis and autonomic nervous functions. These effects might be beneficial in stress-related diseases, suggesting that itopride has clinicopharmacological activities.

  15. Gingival Crevicular Fluid and Salivary Periostin Levels in Non-Smoker Subjects With Chronic and Aggressive Periodontitis : Periostin Levels in Chronic and Aggressive Periodontitis.

    Science.gov (United States)

    Aral, Cüneyt A; Köseoğlu, Serhat; Sağlam, Mehmet; Pekbağrıyanık, Tuğba; Savran, Levent

    2016-06-01

    Periostin, an extracellular matrix protein functioning as an important structural mediator and adhesion molecule, has been shown to be an important regulator of connective tissue integrity. This study aimed to evaluate the levels of periostin in chronic periodontitis (CP) and aggressive periodontitis (AgP) compared to non-periodontitis (NP). Individuals were submitted to gingival crevicular fluid (GCF) and saliva sampling. Periodontal examination consisted of plaque index (PI), gingival index (GI), probing depth (PD), bleeding on probing (BOP), and clinical attachment level (CAL) measurements. Assays for periostin were performed by an enzyme-linked immunosorbent assay. Periodontitis patients presented more severe clinical indices compared to the NP group (p aggressive periodontitis. The results suggest that subjects with CP and AgP exhibit a different periostin profile. Periostin in GCF may have a protective role against periodontal disease. Furthermore, salivary periostin concentrations may have a promising diagnostic potential for the aggressive forms of periodontal disease.

  16. Discrepancies between self-reported years of education and estimated reading level among elderly community-dwelling African-Americans: Analysis of the MOAANS data.

    Science.gov (United States)

    O'Bryant, Sid E; Lucas, John A; Willis, Floyd B; Smith, Glenn E; Graff-Radford, Neill R; Ivnik, Robert J

    2007-03-01

    The influence of education on cognition has received a great deal of attention in the literature. Although there is general consensus regarding the importance of education on cognitive functioning, the extent to which self-reported level of education corresponds to true educational attainment remains unclear, especially in ethnic minority populations where equal access to education has not always been available. Several investigators have suggested that reading skill may serve as a quantitative estimate of true education experience. Among African-Americans, however, research has shown that self-reported educational level consistently over predicts estimated reading level. The current study analyzed the discrepancy between self-reported years of education completed and estimated reading level in a sample of community-dwelling, elderly African-Americans participating in Mayo's Older African Americans Normative Studies (MOAANS) (Lucas, J.A., Ivnik, R.J., Willis, F.B., Ferman, T.J., Smith, G.E., Parfitt, F.C., Petersen, R.C., & Graff-Radford, N.R. (2005). Mayo's Older African Americans Normative Studies: Normative data for commonly used clinical neuropsychological measures. The Clinical Neuropsychologist, 19, 162-183). In this sample, 29% of the participants read at a level that was 3 or more years below what would be expected based on self-report of education attained. This study also sought to evaluate the extent to which this discrepancy fluctuated as a function of demographic variables such as location of schooling (urban, suburban, rural; North vs. South), parental education and literacy, and percentage of segregation in schooling. Implications of these results are discussed, as are areas for further inquiry.

  17. Evaluation and optimization of fMRI single-subject processing pipelines with NPAIRS and second-level CVA.

    Science.gov (United States)

    Zhang, Jing; Anderson, Jon R; Liang, Lichen; Pulapura, Sujit K; Gatewood, Lael; Rottenberg, David A; Strother, Stephen C

    2009-02-01

    In functional magnetic resonance imaging (fMRI) analysis, although the univariate general linear model (GLM) is currently the dominant approach to brain activation detection, there is growing interest in multivariate approaches such as principal component analysis, canonical variate analysis (CVA), independent component analysis and cluster analysis, which have the potential to reveal neural networks and functional connectivity in the brain. To understand the effect of processing options on performance of multivariate model-based fMRI processing pipelines with real fMRI data, we investigated the impact of commonly used fMRI preprocessing steps and optimized the associated multivariate CVA-based, single-subject processing pipelines with the NPAIRS (nonparametric prediction, activation, influence and reproducibility resampling) performance metrics [prediction accuracy and statistical parametric image (SPI) reproducibility] on the Fiswidgets platform. We also compared the single-subject SPIs of univariate GLM with multivariate CVA-based processing pipelines from SPM, FSL.FEAT, NPAIRS.GLM and NPAIRS.CVA software packages (or modules) using a novel second-level CVA. We found that for the block-design data, (a) slice timing correction and global intensity normalization have little consistent impact on the fMRI processing pipeline, but spatial smoothing, temporal detrending or high-pass filtering, and motion correction significantly improved pipeline performance across all subjects; (b) the combined optimization of spatial smoothing, temporal detrending and CVA model parameters on average improved between-subject reproducibility; and (c) the most important pipeline choices include univariate or multivariate statistical models and spatial smoothing. This study suggests that considering options other than simply using GLM with a fixed spatial filter may be of critical importance in determining activation patterns in BOLD fMRI studies.

  18. Haptoglobin 2-2 Genotype Is Associated with TNF-α and IL-6 Levels in Subjects with Obesity

    Directory of Open Access Journals (Sweden)

    Brissia Lazalde

    2014-01-01

    Full Text Available Objective. To evaluate the association between Haptoglobin (HP gene polymorphisms with inflammatory status in obese subjects. Materials and Methods. A cross-sectional study was carried out. A total of 276 apparently healthy men and nonpregnant obese women were enrolled and allocated according to the HP genotype into the HP1/HP1, HP2/HP1, and HP2/HP2 groups. Distribution of HP genotypes was 49, 87, and 140 for the HP1/HP1, HP2/HP1, and HP2/HP2, respectively. The HP genotype was determined using the polymerase chain reaction method. A multiple linear regression analysis adjusted by age, sex, waist circumference, and total body fat was used to determine the association between HP genotypes with TNF-α, IL-6, and high-sensitivity C-reactive protein (hsCRP levels. Results. A multiple linear regression analysis adjusted by sex, waist circumference, and total body fat was performed showing a significant association between the HP2/HP2 genotype and TNF-α (β = 0.180; 95% CI 14.41–159.64, P = 0.01 and IL-6 (β = 0.188; 95% CI 1.53–12.72, P = 0.01 levels, but not with hsCRP (β = −0.008; 95% CI −1.64–1.47, P = 0.914 levels, whereas the HP2/HP1 genotype showed no association compared with the HP1/HP1 genotype (control group. Conclusion. Results of our study show that the HP2/HP2 genotype is associated with elevated TNF-α and IL-6, but not with hsCRP, levels in obese subjects.

  19. Do Students Using Electronic Books Display Different Reading Comprehension and Motivation Levels than Students Using Traditional Print Books?

    Science.gov (United States)

    Wells, Casey L.

    2012-01-01

    The effect of electronic books on the reading comprehension of middle and high school students was examined using an experimental posttest-only control-group design. A convenience sample of 140 randomly assigned middle and high school English students at an independent school in eastern North Carolina participated. Half of the students used…

  20. General Education Teachers' Ratings of the Academic Engagement Level of Students Who Read Braille: A Comparison with Sighted Peers

    Science.gov (United States)

    Bardin, Julie A.; Lewis, Sandra

    2011-01-01

    English and language arts teachers of braille-reading students in general education classes rated these students' academic engagement and the academic achievement of low- and average-achieving sighted students in the same classrooms. The braille readers were found to be statistically similar to the low-achieving students with regard to effort,…

  1. [Strength training improves insulin sensitivity and plasma lipid levels without altering body composition in overweight and obese subjects].

    Science.gov (United States)

    Hernán Jiménez, Oscar; Ramírez-Vélez, Robinson

    2011-04-01

    To assess the effect of long-term strength training on insulin sensitivity, lipid profile, and body composition in overweight and obese subjects. A prospective, randomized, interventional study in 16 overweight or obese subjects aged 18-35years who were investigated before and at the end of 8weeks of strength training. The experimental group (n=8) followed a strength training program consisting of 4 sessions per week at 50% to 80% of repetition maximum (RM), estimated through the 1RM test. The control group (n=8) did not perform the training program. Glucose, insulin, total cholesterol, triglycerides, HDL-C, VLDL-C, and LDL-C levels and arterial index were determined. Insulin sensitivity was measured by calculating HOMA-IR (Homeostatic Model Assessment-Insulin Resistance). Indicators of body composition included weight, height, waist circumference, body fat, fat weight, muscle mass, somatotype chart and distance. At the end of intervention, the experimental group showed a decrease of insulin sensitivity (3.5±0.9 vs. 2.9±1.2; p=0.04), LDL-C (106.9±20.8 vs. 95.5±14.2; p=0.03), and arterial index (4.0±0.6 vs. 3.5±0.5; p=0.01), as well as an increase in HDL-C levels (43.7±8.8 vs. 46.9±5.6; p=0.04), while the control group remained stable. There were no significant differences between groups in body composition, somatotype chart and distance after training. In overweight and obese subjects, strength training for eight weeks improved insulin sensitivity and lipid profile without altering body composition. Copyright © 2011 SEEN. Published by Elsevier Espana. All rights reserved.

  2. Reading Faster

    Science.gov (United States)

    Nation, Paul

    2009-01-01

    This article describes the visual nature of the reading process as it relates to reading speed. It points out that there is a physical limit on normal reading speed and beyond this limit the reading process will be different from normal reading where almost every word is attended to. The article describes a range of activities for developing…

  3. Antibody and cytokine serum levels in patients subjected to anti-rabies prophylaxis with serum-vaccination

    Directory of Open Access Journals (Sweden)

    J. A. Ayres

    2006-01-01

    Full Text Available Rabies is considered a fatal disease once clinical symptoms have developed. The aim of this study was to evaluate epidemiological aspects and immune response in patients attacked by domestic and wild animals and subjected to post-exposure rabies treatment with equine serum and associated vaccine. Thirty-three patients were evaluated; they were between 13 and 65 years old, 75.8% were male and 24.2% female, and from the Botucatu neighborhood. Twenty healthy control individuals with the same age range were also studied. Specific antibodies to equine immunoglobulins and IFN-gamma, IL-2, IL-4, and IL-10 production were evaluated by ELISA. IgM, IgE, IgG and subclasses, and rabies virus antibodies serum levels were determined by nephelometry and seroneutralization methods, respectively. No anaphylactic or serum sickness allergic reactions were observed in patients after treatment. Anti-equine IgG levels were significantly higher than those of IgM after 14 and 28 days of treatment. Protective antibodies to rabies virus > 0.5 UI/ml were detected in 84.6% and 75% of patients at days 14 and 28, respectively. IFN-gamma, IL-2 and IL-10 levels in patients before and 48h after treatment were significantly higher than in controls suggesting that both Th1 and Th2 cells were activated in the patients. Serum IgM levels were higher at day 14, and IgG2 and IgE levels were higher at day 28 of treatment. These results suggest that post-exposure rabies treatment in humans induces significant alterations in patient immune response characterized by increased levels of cytokines, serum levels of specific rabies virus antibodies, and the equine serum components employed in the treatment.

  4. CONSIDERATIONS ABOUT READING COMPREHENSION IN THE SUBJECT ENGLISH FOR ACADEMIC PURPOSES / CONSIDERACIONES SOBRE LA COMPRENSIÓN LECTORA EN LA ASIGNATURA INGLÉS CON FINES GENERALES

    Directory of Open Access Journals (Sweden)

    Graciela Feliciana Mayo Castro

    2013-12-01

    Full Text Available Reading comprehension is one of the general abilities of English language in the teaching-learning process. This skill constitutes a cultural and a work device, and it is the basis that helps to acquire of a great amount of knowledge. This methodological suggestion facilitates the development of reading comprehension due to that it is a system of exercises which are organized in a hierarchical way that leads the students to better decode the message expressed in a text. Reading comprehension ability makes easier to decode a message not only in English language but in Spanish language as well. LA COMPRENSIÓN LECTORA EN LA ASIGNATURA INGLÉS CON FINES GENERALES AUTORAS: DIRECCIÓN PARA CORRESPONDENCIA: Departamento de Idiomas. Universidad de Las Tunas, Cuba. E-mail graciela@ult.edu.cu Fecha de recepción: 21\t-\t08\t-\t2013 Fecha de aceptación:\t30\t-\t11\t-\t2013 RESUMEN La comprensión lectora es una de las habilidades generales en el proceso de enseñanza-aprendizaje del idioma inglés, esta constituye un instrumento de trabajo y de cultura y es la base que facilita el aprendizaje de un gran cúmulo de conocimientos. La presente alternativa metodológica facilita el desarrollo de la habilidad de comprensión lectora pues parte de un sistema de ejercicios jerárquicamente organizados, lo que conllevan al estudiante a una decodificación más acertada del mensaje expresado en los textos. El desarrollo de esta habilidad les permite la decodificación de información tanto en la lengua inglesa como en la lengua materna.

  5. Neurobiological Bases of Reading Comprehension: Insights from Neuroimaging Studies of Word-Level and Text-Level Processing in Skilled and Impaired Readers

    Science.gov (United States)

    Landi, Nicole; Frost, Stephen J.; Mencl, W. Einar; Sandak, Rebecca; Pugh, Kenneth R.

    2013-01-01

    For accurate reading comprehension, readers must first learn to map letters to their corresponding speech sounds and meaning, and then they must string the meanings of many words together to form a representation of the text. Furthermore, readers must master the complexities involved in parsing the relevant syntactic and pragmatic information…

  6. Impact Of Using Joint Productive Activity Approach On Second Language Learners’ Performance In Reading Comprehension At The Basic Education Level In Nigeria

    Directory of Open Access Journals (Sweden)

    HANNA ONYI YUSUF

    2013-01-01

    Full Text Available This study investigated the impact of using joint productive activity on the performance of second language learners in reading comprehension at the basic education level in Nigeria. A sample of forty (40 Junior Secondary II students from Kaduna North and South were used for the study. The study was quasi experimental. Government Junior Secondary School Doka was used as the experimental group while Government Junior Secondary School Makera was used as the control group. Both groups were assessed after six weeks of teaching using two reading comprehension tests. T-test was used to test the hypothesis raised in the study. The findings revealed significant differences in the performance of students taught reading comprehension using joint productive activity. Based on the findings teachers are encouraged to use joint productive activities in teaching reading comprehension. This is a positive deviation from the traditional practice in Nigeria where a teacher is regarded as the sole custodian of knowledge and students are empty tabula rasa who should be passive during class teaching. Teachers need to exploit this new approach by designing teaching comprehension activities that will require second language learners’ collaboration and active participation in accomplishing tasks jointly in class with the teacher.

  7. Dietary Intake of Antioxidants and Serum Levels of Total Antioxidant Status (TAS in MS Patients with that of Normal Subjects

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    ehsan Hejazi

    2007-10-01

    Full Text Available Hejazi E1, Amaani R2, Sharafodin-zadeh N3 1. M.sc Student of Nutritional Sciences, Department of Nutritional, Faculty of Para-Medicine, Jondi-shapour University of Medical Sciences 2. Associate Professor, Department of Nutritional, Faculty of Para-Medicine, Jondi-shapour University of Medical Sciences 3. Assistant Professor, Department of Neurology, Faculty of Medicine, Jondi-shapour University of Medical Sciences Abstract Background: Multiple Sclerosis (MS is a chronic, immune-mediated inflammatory and neurodegenerative disease of the Central Nervous System (CNS, with an etiology that is not yet fully understood. Increasing evidence shows that oxidative stress plays an important role in the pathogenesis of MS. The aim of this study was to compare dietary intake of antioxidants and serum levels of Total Antioxidant Status (TAS in MS patients with that of normal subjects. Materials and methods: Serum levels of TAS and dietary intake of the main antioxidants of twenty one MS patients (16 women were compared with age and gender matched healthy controls. Serum samples were collected and frozen for further spectrophotometer analysis. Food frequency questionnaires and 24-hour dietary recalls for 3 days of all subjects were obtained. Results: There was no significant difference in serum levels of TAS between the two groups. No significant difference was seen in consumption of dietary antioxidant sources between them. Additionally, daily intake of vitamin C, vitamin E, vitamin A, folate and dietary fiber were not significantly different between groups. Conclusion: There is a lack of evidence on the possible relationship and benefits of dietary antioxidant in MS patients. More research is required to assess the effectiveness of diet interventions on antioxidant status in MS patients.

  8. The Effects of the Allain Reading System on Reading Achievement.

    Science.gov (United States)

    Allain, Althea Saizan

    Five hundred second-grade pupils participated in a study of the effect of the Allain Color Pack reading system on reading achievement. Subjects were divided into equal treatment and control groups; each group was stratified according to low, average, and high reading ability determined on the basis of pretests of vocabulary and comprehension. The…

  9. Effect of vitamin supplementation on serum oxidized low-density lipoprotein levels in male subjects with cardiovascular disease risk factors.

    Science.gov (United States)

    Najafpour Boushehri, Saeid; Yusof, Rokiah Mohammad; Nasir Mohammad Taib, Mohammad; Mirzaei, Kamran; Yazdekhasti, Narges; Akbarzadeh, Samad

    2012-07-01

    Oxidized low-density lipoproteins (ox-LDLs) appear to play a significant role in atherogenesis. In fact, circulating ox-LDL concentrations have been recognized as a risk factor for cardiovascular disease (CVD). The main objectives of this study were to assess the effects of antioxidant vitamins on ox-LDL as a biomarker of CVD in male subjects with CVD risk factors. The effect of antioxidant vitamins on ox-LDL as a biomarker of CVD in male subjects with CVD in male subjects with CVD risk factors at baseline and after 12 weeks of supplementation with vitamin E (400 IU), C (500 mg), ß-carotene (15 mg), and the combined supplements (E, C, and ß-carotene) respectively defined as group E, C, B and control group was considered as group P. The mean values for ox-LDL at the baseline were 86.93 ± 26.30 U/l in group C, 94.52 ± 38.40 U/l in group E, 79.73±2.07 U/l in group B, 85.97±23.07 U/l in combined group, and 84.90± 14.66 U/l in group P. After 12 weeks of intervention the percentage of changes for group C, group E, group B, COM group, and group P were (-18.32), (-2286), (-17.31), (-19.01) and (-2.0), respectively. Using Wilcoxon method, significant differences were detected in the mean ox-LDL concentrations of baseline and after intervention, values in the C, E, B and combined groups (PLDL levels.

  10. An investigation into the strength of the association and agreement levels between subjective and objective sleep duration in adolescents.

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    Teresa Arora

    Full Text Available STUDY OBJECTIVES: The majority of adolescent sleep research has utilized self-reported sleep duration and some have based information on a solitary question. Whilst some have claimed to have validated sleep survey data with objective actigraphy measures in adolescents, the statistical approach applied only demonstrates the strength of the association between subjective and objective sleep duration data and does not reflect if these different methods actually agree. METHODS: Data were collected as part of the Midlands Adolescents Schools Sleep Education Study (MASSES. Adolescents (n=225 aged 11-13 years provided estimates for weekday, weekend and combined sleep duration based on self-reported survey data, a 7-day sleep diary, and wrist-worn actigraphy. RESULTS: We assessed the strength of the relationship as well as agreement levels between subjective and objectively determined sleep duration (weekday, weekend and combined. Subjective diary sleep duration was significantly correlated with actigraphy estimates for weekday and weekend sleep duration r=0.30, p ≤ 0.001 and r=0.31, p ≤ 0.001 respectively. Pitman's test demonstrated no significant difference in the variance between weekend sleep duration (r=0.09, p=0.16 and combined sleep duration (r=0.12, p=0.08 indicating acceptable agreement between actigraphy and sleep diary sleep duration only. Self-reported sleep duration estimates (weekday, weekend and combined did not agree with actigraphy determined sleep duration. CONCLUSIONS: Sleep diaries are a cost-effective alternative to survey/questionnaire data. Self-reported measures of sleep duration in adolescents do not agree with actigraphy measures and should be avoided where possible. Previous adolescent sleep studies that have utilized self-reported survey data may not provide a complete representation of sleep on the outcome measure of interest.

  11. Circulating obestatin levels in normal subjects and in patients with impaired glucose regulation and type 2 diabetes mellitus.

    Science.gov (United States)

    Qi, Xiaoya; Li, Ling; Yang, Gangyi; Liu, Jianlei; Li, Ke; Tang, Yi; Liou, Hua; Boden, Guenther

    2007-04-01

    Obestatin is a novel hormone that is encoded by the Ghrelin gene and produced in the gut. Ghrelin is profoundly orexogenic and adipogenic, increasing food intake and body weight. This new ghrelin-associated peptide behaves as a physiological opponent of ghrelin in rodent animals, but its pathophysiological role in humans remains unknown In this study we investigate whether plasma obestatin level is different in patients with impaired glucose regulation (IGR) and type 2 diabetes mellitus (T2DM). Forty-seven patients with T2DMu, 30 subjects with IGR, and 38 sex- and age-matched normal controls participated in the study. Plasma obestatin levels were measured with a radioimmunoassay. The relationship between plasma obestatin levels and anthropometric and metabolic parameters was also analysed. Plasma obestatin levels were lower in patients with T2DM and IGR than in controls (37.5 +/- 9.2 ng/l and 39.2 +/- 9.7 ng/l vs. 43.8 +/- 8.0 ng/l, P = 0.002 and P = 0.039, respectively). Decreasing concentrations of obestatin were independently and significantly associated with IGR and T2DM. Multiple logistic regression analysis revealed obestatin to be independently associated with IGR and T2DM. In a multiple linear regression analysis, only waist-to-hip ratio and homeostasis model assessment of insulin resistance (HOMA-IR) were independently associated with plasma obestatin level. Our results suggest that obestatin may play a role in appetite regulation in patients with IGR and T2DM.

  12. Correlation of lithium levels between drinking water obtained from different sources and scalp hair samples of adult male subjects.

    Science.gov (United States)

    Baloch, Shahnawaz; Kazi, Tasneem Gul; Afridi, Hassan Imran; Baig, Jameel Ahmed; Talpur, Farah Naz; Arain, Muhammad Balal

    2017-10-01

    There is some evidence that natural levels of lithium (Li) in drinking water may have a protective effect on neurological health. In present study, we evaluate the Li levels in drinking water of different origin and bottled mineral water. To evaluate the association between lithium levels in drinking water with human health, the scalp hair samples of male subjects (25-45 years) consumed drinking water obtained from ground water (GW), municipal treated water (MTW) and bottled mineral water (BMW) from rural and urban areas of Sindh, Pakistan were selected. The water samples were pre-concentrated five to tenfold at 60 °C using temperature-controlled electric hot plate. While scalp hair samples were oxidized by acid in a microwave oven, prior to determined by flame atomic absorption spectrometry. The Li content in different types of drinking water, GW, MTW and BMW was found in the range of 5.12-22.6, 4.2-16.7 and 0.0-16.3 µg/L, respectively. It was observed that Li concentration in the scalp hair samples of adult males consuming ground water was found to be higher, ranged as 292-393 μg/kg, than those who are drinking municipal treated and bottle mineral water (212-268 and 145-208 μg/kg), respectively.

  13. A computer-based reading test for use as an index of premorbid general intellectual level in North American English-speaking adults.

    Science.gov (United States)

    Letz, Richard; DiIorio, Colleen K; Shafer, Patricia O; Yeager, Katherine A; Henry, Thomas R; Schomer, Donald L

    2003-08-01

    Brief tests of vocabulary or reading ability are often used as an index of general intellectual level to hypothesize deficits in patients, to establish comparability of comparison groups, and as a covariate of performance on other neuropsychological tests. We evaluated a new variant of a reading test for potential use in estimating premorbid general intellectual ability and implementation as a computerized-adaptive test. A total of 319 outpatients who participated in an epilepsy self-management study were tested on three occasions, completing the Wide-Range Achievement Test-3 (WRAT-3) Reading test at baseline and the NES3 Adult Reading Test (ART) at the 3-month follow-up. At the 6-month follow-up, some participants completed the ART and some the NES2 Vocabulary test. ART and WRAT-3 Reading scores obtained 3 months apart were highly correlated (r=0.87, n=179), while ART and NES2 Vocabulary scores were somewhat less correlated (r=0.80, n=61). The ART test-retest correlation was high (r=0.95, n=79). The ART distribution was spread out more evenly at the high end than that of the WRAT-3 Reading. ART score was significantly related to education, race, income, and examiner category, but was unrelated to age category and depression status. Non-significant gender differences were observed. An item-response theory (Rasch model) analysis showed good fit of the model to the observed data and yielded an improved ranking of the ART items in order of difficulty. The NES3 ART exhibited high reliability and strong association with WRAT-3 Reading. These results suggest that the NES3-ART may be useful as an index of general intellectual ability for comparison of groups and for use as a covariate in data analyses among English-speaking, North American adults. The Rasch model analysis provides a basis for implementing the ART as a computerized-adaptive test, which should improve its time efficiency and reduce participant burden in taking the test.

  14. The estimation of premorbid intelligence levels among Portuguese speakers: the Irregular Word Reading Test (TeLPI).

    Science.gov (United States)

    Alves, Lara; Simões, Mário R; Martins, Cristina

    2012-01-01

    Information regarding cognitive abilities in earlier stages of life is essential to ascertain if and to what extent these may have declined. When unavailable, clinicians rely on estimate methods. One of the contemporary methods used worldwide combines performance on irregular word reading test with demographics since it has shown to provide reliable estimates of premorbid ability. Hence, a reading test portuguese irregular word reading test (TeLPI) was developed, filling an important gap in the neuropsychological evaluation of Portuguese speakers. Using 46 irregular, infrequent Portuguese words, TeLPI was validated against Wechsler Adult Intelligence Scale (WAIS)-III (N = 124), and regression-based equations were determined to estimate premorbid IQ considering TeLPI scores and demographic variables. TeLPI scores accounted for 63% of the variance of WAIS-III Full-Scale IQ, 62% of Verbal IQ, and 47% of Performance IQ and thus were considered valid for premorbid intelligence estimation. © The Author 2011. Published by Oxford University Press. All rights reserved.

  15. Severity of spine malalignment on center of pressure progression during level walking in subjects with adolescent idiopathic scoliosis.

    Science.gov (United States)

    Chern, Jen-Suh; Kao, Chia-Chi; Lai, Po-Lian; Lung, Chi-Wen; Chen, Wen-Jer

    2014-01-01

    Center of pressure (CoP) progression during level walking in subjects with Adolescents Idiopathic Scoliosis (AIS) was measured. Participants were divided into three groups according to scoliosis severity. CoP progression among groups was compared quantitatively and qualitatively. The results showed that scoliosis severity affects CoP progression significantly in the hind-foot and forefoot areas. This result indicated that spine alignment might affect the control of heel, ankle and toe rockers in the ankle-foot complex. The effects of scoliosis severity is mainly on the CoP of right foot plantar surface, indicating asymmetrical influence of IS on bilateral lower limb coordination during walking. These results might contribute to musculoskeletal complains over the apparatus within trunk-foot in the later lives of this population.

  16. Magnetic resonance imaging determined visceral fat reduction associates with enhanced IL-10 plasma levels in calorie restricted obese subjects.

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    Gloria Formoso

    Full Text Available BACKGROUND: Obesity is characterized by a low grade chronic inflammation state. Indeed circulating pro-inflammatory cytokines, such as TNF-α and IL-6, are elevated in obese subjects, while anti-inflammatory cytokines, such as IL-10, appear to be reduced. Cytokines profile improves after weight loss, but how visceral or subcutaneous fat loss respectively affect pro- or anti-inflammatory cytokines plasma levels has not been precisely assessed. Therefore in the present study we correlated changes in circulating cytokine profile with quantitative changes in visceral and subcutaneous adipose tissue depots measured by an ad hoc Magnetic Resonance Imaging (MRI protocol before and after weight loss. MATERIALS AND METHODS: In 14 obese subjects, MRI determination of visceral and subcutaneous fat and plasma glucose, insulin, TNF-α IL-6, and IL-10 measurements were performed before and after a caloric restriction induced weight loss of at least 5% of the original body weight. RESULTS: Weight loss improved insulin sensitivity (QUICKI Index: 0.35±0.03 vs 0.37±0.04; P<0.05, increased IL-10 (3.4±1.9 vs 4.6±1.0 pg/mL; P<0.03, and reduced TNF-α and IL-6 plasma levels (2.5±1.3 vs 1.6±1.5 pg/mL, P<0.0015, 2.3±0.4 vs 1.6±0.6 pg/mL, P<0.02 respectively. A significant correlation was observed between the amount of visceral fat loss and the percentage reduction in both TNF-α (r = 0.56, p<0.05 and IL-6 (r = 0.19 p<0.05 plasma levels. In a multiple regression analysis, the amount of visceral fat loss independently correlated with the increase in IL-10 plasma levels. CONCLUSION: The reduction in visceral adipose tissue is the main driver of the improved inflammatory profile induced by weight loss.

  17. Red Cloud Reading Test: American Indian Form of the Test of Individual Needs in Reading, a Competency Based Test of Reading Skills [and] Instructor's Manual.

    Science.gov (United States)

    Gilliland, Hap

    The oral Red Cloud Reading Test provides a complete analysis of reading level and skills for American Indian students in grades 1-7 or for high school and adult students reading at or below high school levels. The test determines the basic and recreational reading levels, identifies reading problems, determines reading speeds, and analyzes the…

  18. Writing and the 'Subject'

    DEFF Research Database (Denmark)

    Greve, Charlotte

    /reading subject) manifests itself in the material mark on the page. The study shows how this indexical reference to a ‘subject’ is manipulated and used as a mask through which a writer/painter can perform a certain ‘subject’. Through analyses of the various levels on which the ‘subject’ is represented...... in the early as well as the contemporary avant-garde, it becomes clear that the ‘subject’ is an unstable category that can be exposed to manipulation and play. Handwriting is performing as a signature (as an index), but is at the same time similar to the signature of a subject (an icon) and a verbal construct...

  19. Towards the identification of imaging biomarkers in schizophrenia, using multivariate pattern classification at a single-subject level.

    Science.gov (United States)

    Zarogianni, Eleni; Moorhead, Thomas W J; Lawrie, Stephen M

    2013-01-01

    Standard univariate analyses of brain imaging data have revealed a host of structural and functional brain alterations in schizophrenia. However, these analyses typically involve examining each voxel separately and making inferences at group-level, thus limiting clinical translation of their findings. Taking into account the fact that brain alterations in schizophrenia expand over a widely distributed network of brain regions, univariate analysis methods may not be the most suited choice for imaging data analysis. To address these limitations, the neuroimaging community has turned to machine learning methods both because of their ability to examine voxels jointly and their potential for making inferences at a single-subject level. This article provides a critical overview of the current and foreseeable applications of machine learning, in identifying imaging-based biomarkers that could be used for the diagnosis, early detection and treatment response of schizophrenia, and could, thus, be of high clinical relevance. We discuss promising future research directions and the main difficulties facing machine learning researchers as far as their potential translation into clinical practice is concerned.

  20. Effect of Weight Reduction Following Bariatric Surgery on Serum Visfatin and Adiponectin Levels in Morbidly Obese Subjects

    Directory of Open Access Journals (Sweden)

    Mohammad Javad Hosseinzadeh-Attar

    2013-04-01

    Full Text Available Objective: Adipokines are signaling and mediator proteins secreted from adipose tissue. A novel adipokine, visfatin, was reported as a protein which was mainly expressed in visceral adipose tissue. Controversial results have been shown regarding the changes of adipokines following weight reduction. So we investigated the effects of weight reduction on serum concentrations of adiponectin and visfatin in morbidly obese subjects. Methods: 35 severely obese patients (26 females and 9 males, aged 15-58 years, were studied. Anthropometric parameters and biochemical parameters as well as adiponectin and visfatin were analyzed before and 6 weeks after weight reduction. Results: Anthropometric indices decreased significantly. Blood levels of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglyceride were reduced significantly. The reduction of visfatin and the elevation of adiponectin were significant as well. However, other parameters like fasting glucose and insulin did not change. Moreover, we could not find any significant correlation between the change of serum visfatin and that of adiponectin. Conclusions: 6-week weight reduction after bariatric surgery resulted in decreased serum visfatin and increased adiponectin levels. However, we cannot find any significant correlation between changes of adiponectin, visfatin, BMI, waist circumference, and insulin resistance. Further studies with different design are suggested to clarify these associations.

  1. Musical emotions: predicting second-by-second subjective feelings of emotion from low-level psychoacoustic features and physiological measurements.

    Science.gov (United States)

    Coutinho, Eduardo; Cangelosi, Angelo

    2011-08-01

    We sustain that the structure of affect elicited by music is largely dependent on dynamic temporal patterns in low-level music structural parameters. In support of this claim, we have previously provided evidence that spatiotemporal dynamics in psychoacoustic features resonate with two psychological dimensions of affect underlying judgments of subjective feelings: arousal and valence. In this article we extend our previous investigations in two aspects. First, we focus on the emotions experienced rather than perceived while listening to music. Second, we evaluate the extent to which peripheral feedback in music can account for the predicted emotional responses, that is, the role of physiological arousal in determining the intensity and valence of musical emotions. Akin to our previous findings, we will show that a significant part of the listeners' reported emotions can be predicted from a set of six psychoacoustic features--loudness, pitch level, pitch contour, tempo, texture, and sharpness. Furthermore, the accuracy of those predictions is improved with the inclusion of physiological cues--skin conductance and heart rate. The interdisciplinary work presented here provides a new methodology to the field of music and emotion research based on the combination of computational and experimental work, which aid the analysis of the emotional responses to music, while offering a platform for the abstract representation of those complex relationships. Future developments may aid specific areas, such as, psychology and music therapy, by providing coherent descriptions of the emotional effects of specific music stimuli. 2011 APA, all rights reserved

  2. Reading Comics

    Science.gov (United States)

    Tilley, Carol L.

    2008-01-01

    Many adults, even librarians who willingly add comics to their collections, often dismiss the importance of comics. Compared to reading "real" books, reading comics appears to be a simple task and compared to reading no books, reading comics might be preferable. After all, comics do have words, but the plentiful pictures seem to carry most of the…

  3. The Effects of Abstract Reasoning Ability, Degree of Bidialectism, and Grade Level on the Performance of Black, Inner-City Children on Equivalent Reading Tasks Presented in Standard English, Black English Standard Orthography, and Black English Nonstandard Orthography.

    Science.gov (United States)

    Harber, Jean Rosner

    This research studied the effects of abstract-reasoning ability, degree of bidialectism, and grade level on listening comprehension tasks presented in both Standard English and Black English and on oral reading and oral-reading comprehension tasks presented in Standard English, Black English standard orthography, and Black English nonstandard…

  4. Device for improving quantification of reading acuity and reading speed.

    Science.gov (United States)

    Dexl, Alois K; Schlögel, Horst; Wolfbauer, Michael; Grabner, Günther

    2010-09-01

    To present a new device, the Salzburg Reading Desk (SRD), for the standardized testing of reading acuity and reading speed at a subjectively convenient reading distance (best distance). First, in a systematic experimental setup, testing for validity and reliability was performed at 450 simulated reading distances (90 different test situations, each repeated 5 times) between 16 and 70 cm. The distance read-outs by the SRD software were correlated to the distances measured with a meter ruler. Second, reading distance and reading speed of 27 naturally emmetropic and presbyopic patients were evaluated using the log-scaled Radner Reading Charts implemented in the SRD. In the experimental setup, an overall mean difference of the SRD distance read-out-compared to a standard distance measurement with a meter ruler-of 0.08±0.13 cm was observed. In the presbyopic patients, overall mean reading distance was 49.74±4.43 cm. Patients were able to read with their own subjectively convenient reading distance. A constant mean reading speed of sentences with bigger typeface (between 152.4±22.6 words/minute [wpm] and 157.3±15.8 wpm) was found, but reading speed gradually diminished over time when reading sentences with smaller typeface. The SRD seems to be a valid and reliable device for testing reading acuity at the best reading distance in an experimental setup as well as in clinical use in presbyopic patients. The SRD may be used whenever a detailed comparison of different methods for correcting presbyopia is required. Copyright 2010, SLACK Incorporated.

  5. Different FDG-PET metabolic patterns at single-subject level in the behavioral variant of fronto-temporal dementia.

    Science.gov (United States)

    Cerami, Chiara; Dodich, Alessandra; Lettieri, Giada; Iannaccone, Sandro; Magnani, Giuseppe; Marcone, Alessandra; Gianolli, Luigi; Cappa, Stefano F; Perani, Daniela

    2016-10-01

    The diagnosis of probable behavioral variant of fronto-temporal dementia (bvFTD) according to current criteria requires the imaging evidence of frontal and/or anterior temporal atrophy or hypoperfusion/hypometabolism. Different variants of this pattern of brain involvement may, however, be found in individual cases, supporting the presence of heterogeneous phenotypes. We examined in a case-by-case approach the FDG-PET metabolic patterns of patients fulfilling clinical criteria for probable bvFTD, assessing the presence and frequency of specific FDG-PET features. Fifty two FDG-PET scans of probable bvFTD patients were retrospectively analyzed together with clinical and neuropsychological data. Neuroimaging experts rated the FDG-PET hypometabolism maps obtained at the single-subject level with optimized voxel-based Statistical Parametric Mapping (SPM). The functional metabolic heterogeneity was further tested by hierarchical cluster analysis and principal component analysis (PCA). Both the SPM maps and cluster analysis identified two major variants of cerebral hypometabolism, namely the "frontal" and the "temporo-limbic", which were correlated with different cognitive profiles. Executive and language deficits were the cognitive hallmark in the "frontal" subgroup, while poor encoding and recall on long-term memory tasks was typical of the "temporo-limbic" subgroup. SPM single-subject analysis indicates distinct patterns of brain dysfunction in bvFTD, coupled with specific clinical features, suggesting different profiles of neurodegenerative vulnerability. These findings have important implications for the early diagnosis of bvFTD and for the application of the recent international consensus criteria. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. The Influence of Gender, Grade Level and Favourite Subject on Czech Lower Secondary School Pupils' Perception of Geography

    Science.gov (United States)

    Kubiatko, Milan; Janko, Tomas; Mrazkova, Katerina

    2012-01-01

    Geography is an important school subject that brings pupils' description and explanation of social, economic and/or political aspects of the changing world. It has been affirmed that the interest in a subject depends on the attitude to this subject. This study investigates Czech lower secondary school pupils' perception of geography. The research…

  7. THE ROLE OF GENDER IN READING COMPREHENSION: AN ANALYSIS OF COLLEGE-LEVEL EFL STUDENTS’ COMPREHENSION OF DIFFERENT GENRES

    Directory of Open Access Journals (Sweden)

    Didem Koban Koç

    2016-07-01

    Full Text Available The purpose of the present study is to examine the effects of gender on comprehending different types of genre. The study involved 60 first year college students (30 males and 30 females who were taking an advanced reading course at a government university in Turkey. The students were given three reading passages of different genres such as historical fiction, essay and fantasy and were asked to answer comprehension questions related to the passages. Descriptives statistics, one-way ANOVA and repeated measures ANOVA were employed to analyse the relationship between gender and the test scores for each text type. The results showed that (1 the participants, in general, were significantly better at understanding the essay than historical fiction and fantasy (2 there was not a statistically significant difference between males and females regarding comprehending the different types of genres (3 both the male and female participants were significantly better at understanding the essay than historical fiction and fantasy. The study offers suggestions regarding incorporating different types of genre in the classroom.

  8. Improve your reading

    CERN Document Server

    Fry, Ron

    2012-01-01

    Help your students discover the practical solution to their reading frustrations, with Improve Your Reading. Written by bestselling author and education advocate Ron Fry, this book avoids gimmicks and tricks in favor of proven strategies that will help your students better retain and comprehend what they've read in any textbook, in any course, at any academic level. Endlessly adaptable to each student's individual learning needs, the text focuses on fundamental skills students can carry beyond the classroom.

  9. Reading Journal as a Way to Improve Students' Comprehension Toward a Textbook Reading Material

    OpenAIRE

    Winiharti, Menik; Herawati, Agnes; Rahayu, Esti

    2014-01-01

    Reading journal is one way to record students' independent learning based on text they read. This study was conducted to find out the students' level of reading comprehension through some notes written in the reading journal, the extent to which the activity of writing reading journals improved students' reading comprehension, whether the students got benefit from reading journal. There were 104 respondents coming from four different departments in Bina Nusantara University were asked to read...

  10. READING JOURNAL AS A WAY TO IMPROVE STUDENTS’ COMPREHENSION TOWARD A TEXTBOOK READING MATERIAL

    OpenAIRE

    Menik Winiharti; Agnes Herawati; Esti Rahayu

    2014-01-01

    Reading journal is one way to record students’ independent learning based on text they read. This study was conducted to find out the students’ level of reading comprehension through some notes written in the reading journal, the extent to which the activity of writing reading journals improved students’ reading comprehension, whether the students got benefit from reading journal. There were 104 respondents coming from four different departments in Bina Nusantara University were asked to read...

  11. The Effect of College Students' Self-Generated Computerized Mind Mapping on Their Reading Achievement

    Science.gov (United States)

    Sabbah, Sabah Salman

    2015-01-01

    This study explored the potential effect of college students' self-generated computerized mind maps on their reading comprehension. It also investigated the subjects' attitudes toward generating computerized mind maps for reading comprehension. The study was conducted in response to the inability of the foundation-level students, who were learning…

  12. The Impact of Training Metacognitive Strategies on Reading Comprehension among ESL Learner's

    Science.gov (United States)

    Habibian, Maryam

    2015-01-01

    The present study investigates the impact of training metacognitive strategies in reading comprehension and has been conducted among students from University Putra Malaysia. Forty eight subjects majoring in English including both males and females participated in the study. They have been chosen from first level of reading and divided into two…

  13. The effects of phytosterol in low fat milk on serum lipid levels among mild-moderately hypercholesterolemic subjects

    Directory of Open Access Journals (Sweden)

    Sri Sukmaniah

    2008-03-01

    Full Text Available One of the most important risk factors for CHD is dyslipidemia, among others hypercholesterolemia or high LDL-cholesterol. Plant-sterols or phytosterols (PS are among dietary factors known to lower blood cholesterol as part of therapeutic life-style changes diet. This study was aimed to evaluate the effect of PS properly solubilized in a-partly vegetable oil-filled low fat milk, on serum lipid levels in mild-moderate hypercholesterolemic subjects. Randomized, two-arm parallel control group trial was conducted at Department of Nutrition-University of Indonesia in Jakarta from June to November 2006. Each subject was randomly assigned to receive dietary life-style changes counseling plus 1.2 g phytosterol/day in low-fat milk (PS-group or control group receiving the counseling alone for six weeks period. There were no significant changes of serum total and LDL-cholesterol of control group after a six week of dietary counseling (respectively 218.3 ± 18.6 mg/dL to 219.6 ± 24.3 mg/dL and 164.7±21.8 mg/dL to 160.0±26.4 mg/dL. There were a significant decreases of serum total and LDL-cholesterol (respectively p=0.01 and p=0.004 among subjects receiving PS after a six weeks observation period (respectively 233.5±24.6 mg/dL to 211.2±30.3 mg/dL and 176.9±24.7 mg/dL to 154.5±24.3 mg/dL. There was a significant difference in the LDL-lowering effects (p=0.024 among the PS-group after a six weeks (22.4±27.9 mg/dL as compared to the control group (4.7±17.2 mg/dL. No significant changes were found on serum HDL-cholesterol and triglyceride levels in both groups. Although there was no significant difference found in daily nutrients intake between the-2 groups, however, significant reductions in body weight, body mass index and waist circumference were found only in the PS group (p=0.000; 0.000; 0.003, respectively. It is concluded that the lowering of total and LDL-cholesterol in those receiving life-style changes counseling plus 1.2 g PS daily for six

  14. Integrin α(IIb)β₃ exists in an activated state in subjects with elevated plasma homocysteine levels.

    LENUS (Irish Health Repository)

    McGarrigle, Sarah A

    2011-01-01

    Elevated levels of plasma homocysteine (Hcy) are an independent risk factor for cardiovascular disease and thrombosis. The molecular basis for this phenomenon is not known but may relate to modification of cell surface thiols. The platelet specific integrin α(IIb)β₃ is a cysteine-rich cell adhesion molecule that plays a critical role in platelet aggregation and adhesion in haemostasis and thrombosis. In this study, we looked for evidence of a homocysteine-induced modification of α(IIb)β₃ using a fluorescently labeled PAC-1 antibody that recognizes the activated conformation of the integrin on the platelet surface. We show that exogenous Hcy (10-100 µM) and homocysteine thiolactone (HcyTL) (10-100 µM) increased PAC-1 binding to platelets in a concentration dependent manner in vitro. In parallel, we show subjects with clinical hyperhomocysteinemia exhibit a greater degree of activation of α(IIb)β₃ compared to age-matched controls. These findings demonstrate that circulating Hcy can modulate the activation state of the platelet integrin α(IIb)β₃, a key player in platelet aggregation and thrombosis.

  15. Loosely coupled level sets for retinal layers and drusen segmentation in subjects with dry age-related macular degeneration

    Science.gov (United States)

    Novosel, Jelena; Wang, Ziyuan; de Jong, Henk; Vermeer, Koenraad A.; van Vliet, Lucas J.

    2016-03-01

    Optical coherence tomography (OCT) is used to produce high-resolution three-dimensional images of the retina, which permit the investigation of retinal irregularities. In dry age-related macular degeneration (AMD), a chronic eye disease that causes central vision loss, disruptions such as drusen and changes in retinal layer thicknesses occur which could be used as biomarkers for disease monitoring and diagnosis. Due to the topology disrupting pathology, existing segmentation methods often fail. Here, we present a solution for the segmentation of retinal layers in dry AMD subjects by extending our previously presented loosely coupled level sets framework which operates on attenuation coefficients. In eyes affected by AMD, Bruch's membrane becomes visible only below the drusen and our segmentation framework is adapted to delineate such a partially discernible interface. Furthermore, the initialization stage, which tentatively segments five interfaces, is modified to accommodate the appearance of drusen. This stage is based on Dijkstra's algorithm and combines prior knowledge on the shape of the interface, gradient and attenuation coefficient in the newly proposed cost function. This prior knowledge is incorporated by varying the weights for horizontal, diagonal and vertical edges. Finally, quantitative evaluation of the accuracy shows a good agreement between manual and automated segmentation.

  16. Behavioral, autonomic, and subjective reactions to low- and moderate-level simulated sonic booms : a report of two experiments and a general evaluation of sonic boom startle effects.

    Science.gov (United States)

    1974-09-01

    Two separate studies are reported. The first attempted to determine a sonic boom exposure level below which startle reactions would not occur. Subjects were exposed indoors to six simulated sonic booms having various outside overpressures. In the sec...

  17. Ways students read texts

    Science.gov (United States)

    Wandersee, James H.

    College students responding to the Preferred Method of Study (PMOS) questionnaire explained how they approach reading a new textbook chapter for comprehension. Results indicated that a significant positive correlation exists between the number of passes a student makes at new textbook material and his/her college grade-point average. Women showed a significant preference for adopting a single method of study. Less than half of the students queried construct organizational tools such as outlines or diagrams as they study a textbook. Students said they would alter their textbook strategies in response to the type of test they expected significantly more often than they would for the type of subject matter being studied. Only 6% of the students said they make a conscious effort to link the new concepts in the text to prior knowledge. There was no discernable relationship between the study strategies undergraduate college students employ and their college grade level (freshman through senior).

  18. SUBJECTIVE AND OBJECTIVE ESTIMATION OF THE LEVEL OF PHYSICAL EDUCATION IN SERVICE OF CONSERVING HEALTH STATUS IMPROVEMENT

    Directory of Open Access Journals (Sweden)

    Dragan Krivokapić

    2014-06-01

    . One of the most important publications in which this connection is emphasized is the report of the American Ministry of Health, called Physical activity and health (1996, which gives a number of useful effects on health status of people who participated in some form of physical activity. Exact minimal volume and intensity of physical activity enough to cause positive effects on health status is still unknown, so the estimation of elements of physical form related to health became important for many institutions occupied with health of people. Discussion: For each of the above mentioned elements of physical form related to health, there were different subjective and objective procedures established that can be used for their estimation. Carpensen CJ. Powell KE, Cristenson GM Besides (1985, it is very important to take into account a clear aim for which a certain estimation is done, because it enables implementation of the most appropriate protocol for estimation of each element of physical form. In that sense, subjective and objective estimation of the level of physical activity of an individual is essential for preservation and improvement of their health status. References: American College for Sports Medicine, Guildelines for exericise testing and Prescription.8th ed. Philadelphia: 2009 Lippincott Williams&Wilkins, 248-52. Carpensen CJ, Powell KE, Cristenson GM (1985. Physical activity , ehercise, and physical fitness: definitions and distinctions for healt-related research. Public Health Rep., 100(2, 126-31. U.S. Department of Healt and Human Services and Centers for DiseaseControl and Prevention. Physical Activity and health: A report of the Surgeon General. Atlanta (GA: 1996 National Center for Chronic Disease Prevention and Health Promotion, 89-90.

  19. A reading enrichment program for gifted adolescent

    Directory of Open Access Journals (Sweden)

    Silvia Morales Silva

    2008-06-01

    Full Text Available This descriptive research examines the performance on reading comprehension of four gifted adolescents participating in a reading enrichment program. This performance is related to the variables associated to the gifted performance following the model developed by Mönks: motivation, creativity, high ability, school, peers and family. Results showed that school does not satisfy the cognitive needs of these students and it does not offer the required social support either. The family provides the main social support. The motivation, creativity, the high level of language and concentration of the participants facilitate learning. The reading program is described by the participants as motivating due to the subject-matters and methodology; furthermore, due to the opportunity to deal with peers who have a similar cognitive level.

  20. Novel Reading Maturity Scale.

    Science.gov (United States)

    Reich, Carol

    Designed to assess the maturity level of the novels which students read, the Novel Reading Maturity Scale (NRMS) is based on the notion that fiction of high quality is characterized by a number of themes or topics. The list of 22 topics in NRMS came from a survey of several guides on books for teenagers. To explore the reliability of the scale,…

  1. Scientific Versus Humanistic Approaches to Reading.

    Science.gov (United States)

    Thompson, Mark E.

    The scientific approach with humans is usually subject to many human and environmental variables that are difficult to control. Reading behavior and reading disability are two of the most researched topics in education and psychology, yet reading research continues to abound with contradictions. Standardized tests, speed reading, and computer…

  2. Subjective quality of videos displayed with local backlight dimming at different peak white and ambient light levels

    DEFF Research Database (Denmark)

    Mantel, Claire; Korhonen, Jari; Forchhammer, Søren

    2015-01-01

    In this paper the influence of ambient light and peak white (maximum brightness) of a display on the subjective quality of videos shown with local backlight dimming is examined. A subjective experiment investigating those factors is set-up using high contrast test sequences. The results are firstly...

  3. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects

    DEFF Research Database (Denmark)

    Rasmussen, M H; Hvidberg, A; Juul, A

    1995-01-01

    In the present study, we 1) determined whether the impaired spontaneous 24-h GH secretion as well as the blunted GH response to provocative testing in obese subjects are persistent disorders or transient defects reversed with weight loss and 2) investigated 24-h urinary GH excretion and basal...... levels of insulin-like growth factor-I (IGF-I), IGF-binding protein-3 (IGFBP-3), as well as insulin in obese subjects before and after a massive weight loss. We studied 18 obese subjects (age, 26 +/- 1 yr; body mass index, 40.9 +/- 1.1 kg/m2); 18 normal age-, and sex-matched control subjects; and 9...... reversible defects in 24-h spontaneous GH release profiles, basal IGF-I levels, and the IGF-I/IGFBP-3 molar ratio in obese subjects. The recovery of the 24-h GH release points to an acquired transient defect rather than a persistent preexisting disorder....

  4. Spinal loads and trunk muscles forces during level walking - A combined in vivo and in silico study on six subjects.

    Science.gov (United States)

    Arshad, Rizwan; Angelini, Lorenza; Zander, Thomas; Di Puccio, Francesca; El-Rich, Marwan; Schmidt, Hendrik

    2017-08-26

    During level walking, lumbar spine is subjected to cyclic movements and intricate loading of the spinal discs and trunk musculature. This study aimed to estimate the spinal loads (T12-S1) and trunk muscles forces during a complete gait cycle. Six men, 24-33years walk barefoot at self-selected speed (4-5km/h). 3D kinematics and ground reaction forces were recorded using a motion capturing system and two force plates, implemented in an inverse dynamic musculoskeletal model to predict the spinal loads and trunk muscles forces. Additionally, the sensitivity of the intra-abdominal pressure and lumbar segment rotational stiffness was investigated. Peak spinal loads and trunk muscle forces were between the gait instances of heel strike and toe off. In L4-L5 segment, sensitivity analysis showed that average peak compressive, antero-posterior and medio-lateral shear forces were 130-179%, 2-15% and 1-6%, with max standard deviation (±STD) of 40%, 6% and 3% of the body weight. Average peak global muscles forces were 24-55% (longissimus thoracis), 11-23% (iliocostalis thoracis), 12-16% (external oblique), 17-25% (internal oblique) and 0-8% (rectus abdominus) of body weight whereas, the average peak local muscles forces were 11-19% (longissimus lumborum), 14-31% (iliocostalis lumborum) and 12-17% (multifidus). Maximum±STD of the global and local muscles forces were 13% and 8% of the body weight. Large inter-individual differences were found in peak compressive and trunk muscles forces whereas the sensitivity analysis also showed a substantial variation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Non-coding RNA identification based on topology secondary structure and reading frame in organelle genome level.

    Science.gov (United States)

    Wu, Cheng-Yan; Li, Qian-Zhong; Feng, Zhen-Xing

    2016-01-01

    Non-coding RNA (ncRNA) genes make transcripts as same as the encoding genes, and ncRNAs directly function as RNAs rather than serve as blueprints for proteins. As the function of ncRNA is closely related to organelle genomes, it is desirable to explore ncRNA function by confirming its provenance. In this paper, the topology secondary structure, motif and the triplets under three reading frames are considered as parameters of ncRNAs. A method of SVM combining the increment of diversity (ID) algorithm is applied to construct the classifier. When the method is applied to the ncRNA dataset less than 80% sequence identity, the overall accuracies reach 95.57%, 96.40% in the five-fold cross-validation and the jackknife test, respectively. Further, for the independent testing dataset, the average prediction success rate of our method achieved 93.24%. The higher predictive success rates indicate that our method is very helpful for distinguishing ncRNAs from various organelle genomes. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Developing Reading Ability in the Content Fields.

    Science.gov (United States)

    Karlin, Robert

    Subject-area teachers are not expected to be reading experts, but they can help students overcome reading difficulties. Students often fail to meet the subject-matter demands due to lack of purpose in reading content, unfamiliarity with technical vocabulary, and the heavy concept load and idea density in the material. Teachers can use reading…

  7. The Relationship between Reading Comprehension Strategies and Reading Attitudes

    Science.gov (United States)

    Kirmizi, Fatma Susar

    2011-01-01

    The aim of this study is to determine the relationship between levels of reading comprehension strategy use, reading attitudes, and the amount of reading per year among elementary school students. The study was conducted with 1316 students (649 girls and 667 boys) attending the fourth and fifth grades of 15 elementary schools in Denizli, Turkey.…

  8. Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects

    DEFF Research Database (Denmark)

    Vestergaard, H; Weinreb, J E; Rosen, A S

    1995-01-01

    A major pathological feature of noninsulin-dependent diabetes (NIDDM) is defective insulin-stimulated glucose transport in skeletal muscle. When NIDDM subjects are assessed as a group, GLUT4 gene expression in skeletal muscle varies widely and is not different from that in controls. Thus, longitu......A major pathological feature of noninsulin-dependent diabetes (NIDDM) is defective insulin-stimulated glucose transport in skeletal muscle. When NIDDM subjects are assessed as a group, GLUT4 gene expression in skeletal muscle varies widely and is not different from that in controls. Thus......, longitudinal studies are needed to assess whether changes in GLUT4 expression in muscle of NIDDM subjects could be responsible for changes in glucose disposal. The question is timely because recent studies in transgenic mice show that increasing GLUT4 expression can increase insulin-stimulated glucose uptake...... in vivo and in vitro. Here we use a longitudinal design to investigate the effects of 8 weeks of therapy with the sulfonylurea gliclazide on glycemic control, glucose tolerance, insulin-stimulated glucose disposal, and GLUT4 expression in muscle of 10 obese NIDDM subjects. Subjects were on a weight...

  9. Reading comprehension in Parkinson's disease.

    Science.gov (United States)

    Murray, Laura L; Rutledge, Stefanie

    2014-05-01

    Although individuals with Parkinson's disease (PD) self-report reading problems and experience difficulties in cognitive-linguistic functions that support discourse-level reading, prior research has primarily focused on sentence-level processing and auditory comprehension. Accordingly, the authors investigated the presence and nature of reading comprehension in PD, hypothesizing that (a) individuals with PD would display impaired accuracy and/or speed on reading comprehension tests and (b) reading performances would be correlated with cognitive test results. Eleven adults with PD and 9 age- and education-matched control participants completed tests that evaluated reading comprehension; general language and cognitive abilities; and aspects of attention, memory, and executive functioning. The PD group obtained significantly lower scores on several, but not all, reading comprehension, language, and cognitive measures. Memory, language, and disease severity were significantly correlated with reading comprehension for the PD group. Individuals in the early stages of PD without dementia or broad cognitive deficits can display reading comprehension difficulties, particularly for high- versus basic-level reading tasks. These reading difficulties are most closely related to memory, high-level language, and PD symptom severity status. The findings warrant additional research to delineate further the types and nature of reading comprehension impairments experienced by individuals with PD.

  10. VOCABULARY CONSTRAINT ON READING MATERIALS

    Directory of Open Access Journals (Sweden)

    Cucu Sutarsyah

    2016-02-01

    Full Text Available The aim of the study is to identify and describe the vocabulary in reading materials and to seek if the texts are useful for reading skill development. A descriptive qualitative design was applied to obtain the data. Some available computer programs were used to find the description of vocabulary in the texts. It was found that the texts are dominated by low frequency words which compose 16.97% of the words in the texts. In terms of high frequency words occurring in the texts, function words dominate the texts. In the case of word levels, it was found that the texts being used have very limited number of words from GSL (West, 1953. The proportion of the first 1,000 words of GSL only comprises 44.6%. The data also show that the texts contain too large proportion of words which are not in the three levels (the first 2,000 and UWL. These words constitute account for 26.44% of the running words in the texts.  It is believed that the constraints are due to the selection of the texts which are made of a series of short-unrelated texts. This kind of text is subject to the accumulation of low frequency words especially those of content words and limited of words from GSL. It could also impede the development of students' reading skills and vocabulary enrichment.

  11. Which Book and Why: Using Book Bands and Book Levels for Guided Reading in Key Stage 1 [Includes CD-ROM

    Science.gov (United States)

    Bodman, Sue, Ed.; Franklin, Glen, Ed.

    2014-01-01

    We want all children to love reading, and Which Book and Why demonstrates how effective guided reading for children in Foundation Stage and Key Stage 1 can help teachers make this happen. Balancing theory and practice, this book explores how schools and teachers can implement guided reading more confidently and more effectively. Which Book and Why…

  12. Assessment of torque-steadiness reliability at the ankle level in healthy young subjects: implications for cerebral palsy

    DEFF Research Database (Denmark)

    Bandholm, Thomas; Rose, Martin Høyer; Sonne-Holm, Stig

    2008-01-01

    muscle activity (EMG) data. Eighteen young subjects (12.8 +/- 3.1 years, mean +/- 1 SD) were examined twice. At each visit, fluctuations in exerted torque (torque steadiness) and muscle activity from the tibialis anterior, gastrocnemius and soleus muscles were determined during submaximal isometric dorsi...... and plantarflexions. The relative reliability of the torque steadiness variables was substantial (0.80 muscle activity data was generally moderate (0.51 ...It was the primary objective of this study to investigate whether quantifying fluctuations in dorsi and plantarflexor torque during submaximal isometric contractions is a reliable measurement in young healthy subjects. A secondary objective was to investigate the reliability of the associated...

  13. Performance Levels in Science and Other Subjects for Jamaican Adolescents Attending Single-Sex and Co-Educational High Schools.

    Science.gov (United States)

    Hamilton, Marlene A.

    1985-01-01

    Examination results from 1146 Jamaican high school students in single-sex and coeducational schools indicated students from coeducational schools had lower performance on all measures. A subsample provided more information on sex differences, performance in individual subjects, and students receiving grades of A or B. (DH)

  14. The effect of laserpuncture at the LI4 Hegu point on the plasma levels of β-endorphin in healthy subjects

    Science.gov (United States)

    Mihardja, H.; Srilestari, A.; Budianto, S. A.

    2017-08-01

    Laserpuncture is an acupuncture method for pain management. The goal of this study was to determine the effect of laserpuncture at the LI4 Hegu point on the plasma levels of β-endorphin in healthy subjects. A randomized, double-blind, controlled trial with placebo controls was conducted on 29 healthy subjects. Subjects were allocated into the laserpuncture group (n = 15) and the laserpuncture placebo group (n = 14). The plasma levels of β-endorphin were used to measure the output of the study assessed both before treatment and posttreatment. There are statistically significant differences in the mean plasma levels of β-endorphin before and after treatment in the laserpuncture group: changes in mean value from 0.22±0.06 ng/ml to 0.29±0.07 ng/ml with a p value = 0.005 (p placebo group: changes in mean value from 0.22±0.06 ng/ml to 0.26±0.09 ng/ml with p value = 0.195 (p > 0.05). Between groups, there was not a statistically significant difference in the baseline mean plasma levels of β-endorphin (p = 0.183, p > 0.05). The conclusion of this study is that laserpuncture can affect the plasma levels of β-endorphin in healthy subjects when there is no statistically significant difference in the mean plasma levels of β-endorphin between groups.

  15. Comparison of reading speed with 3 different log-scaled reading charts.

    Science.gov (United States)

    Buari, Noor Halilah; Chen, Ai-Hong; Musa, Nuraini

    2014-01-01

    A reading chart that resembles real reading conditions is important to evaluate the quality of life in terms of reading performance. The purpose of this study was to compare the reading speed of UiTM Malay related words (UiTM-Mrw) reading chart with MNread Acuity Chart and Colenbrander Reading Chart. Fifty subjects with normal sight were randomly recruited through randomized sampling in this study (mean age=22.98±1.65 years). Subjects were asked to read three different near charts aloud and as quickly as possible at random sequence. The charts were the UiTM-Mrw Reading Chart, MNread Acuity Chart and Colenbrander Reading Chart, respectively. The time taken to read each chart was recorded and any errors while reading were noted. Reading performance was quantified in terms of reading speed as words per minute (wpm). The mean reading speed for UiTM-Mrw Reading Chart, MNread Acuity Chart and Colenbrander Reading Chart was 200±30wpm, 196±28wpm and 194±31wpm, respectively. Comparison of reading speed between UiTM-Mrw Reading Chart and MNread Acuity Chart showed no significant difference (t=-0.73, p=0.72). The same happened with the reading speed between UiTM-Mrw Reading Chart and Colenbrander Reading Chart (t=-0.97, p=0.55). Bland and Altman plot showed good agreement between reading speed of UiTM-Mrw Reading Chart with MNread Acuity Chart with the Colenbrander Reading Chart. UiTM-Mrw Reading Chart in Malay language is highly comparable with standardized charts and can be used for evaluating reading speed. Copyright © 2013 Spanish General Council of Optometry. Published by Elsevier Espana. All rights reserved.

  16. Combination of benzoyl peroxide 5% gel with liquid cleanser and moisturizer SPF 30 in acne treatment results in high levels of subject satisfaction, good adherence and favorable tolerability.

    Science.gov (United States)

    Kim, Mi-Ran; Kerrouche, Nabil

    2017-07-05

    Skin care products (cleansers and moisturizers) to complement benzoyl peroxide (BPO) in the treatment of acne may improve treatment tolerability and adherence. Evaluate subject satisfaction after use of BPO 5% gel in combination with liquid cleanser and moisturizer SPF 30. Open-label study including subjects aged ≥12 years with mild-to-moderate facial acne; ClinicalTrials.gov Identifier: NCT02589405. Once daily BPO 5% gel, twice daily liquid cleanser and once daily moisturizer SPF 30 were applied for 12 weeks. Assessments included a subject satisfaction questionnaire, investigator global assessment of improvement, lesion counts, the presence of Propionibacterium acnes, and safety. Fifty subjects were enrolled. Most subjects were overall satisfied with the three-part regimen (87%) and felt better about themselves (94%). Subjects indicated the skin care products helped prepare the skin for treatment (85%), relieve itchy skin (81%) and reduce irritation (87%). Most subjects considered that the liquid cleanser (80%) and moisturizer SPF 30 (84%) were a necessary part of acne treatment. BPO reduced P. acnes load by 89% at week 1. The treatment was well tolerated. The combination of BPO 5% gel with liquid cleanser and moisturizer SPF 30 resulted in high levels of subject satisfaction, good tolerability and treatment adherence.

  17. Sweet Temptations: How Does Reading a Fotonovela About Diabetes Affect Dutch Adults with Different Levels of Literacy?

    NARCIS (Netherlands)

    Koops van 't Jagt, Ruth; Hoeks, Jacobus; Duizer, E.; Baron, M.; Molina, G. B.; Unger, J. B.; Jansen, C. J. M.

    2017-01-01

    Recent studies suggest that health-related fotonovelas—booklets that portray a dramatic story using photographs and captions—may be effective health communication tools, especially for readers with a low level of literacy. In this experiment, effects on knowledge and behavioral intentions were

  18. Impact of Serum Triglyceride and High Density Lipoprotein Cholesterol Levels on Early-Phase Insulin Secretion in Normoglycemic and Prediabetic Subjects

    Directory of Open Access Journals (Sweden)

    Masanori Shimodaira

    2014-08-01

    Full Text Available BackgroundIncreased triglycerides (TGs and decreased high density lipoprotein cholesterol (HDL-C levels are established as diabetic risks for nondiabetic subjects. The aim of this study was to investigate the relationship among TG, HDL-C, TG/HDL-C ratio, and early-phase insulin secretion in normoglycemic and prediabetic subjects.MethodsWe evaluated 663 Japanese subjects who underwent the 75-g oral glucose tolerance test. On the basis of these results, the subjects were divided into four groups: those with normal glucose tolerance (NGT; n=341, isolated impaired fasting glucose (i-IFG; n=211, isolated impaired glucose tolerance (i-IGT; n=71, and combined IFG and IGT (IFG+IGT; n=40. Insulin secretion was estimated by the insulinogenic index (IGI (Δinsulin/Δglucose [30 to 0 minutes] and disposition index (DI (IGI/homeostasis model assessment of insulin resistance.ResultsIn prediabetic subjects (i-IFG, i-IGT, and IFG+IGT, linear regression analyses revealed that IGI and DI were positively correlated with HDL-C levels. Moreover, in subjects with i-IGT and (IFG+IGT, but not with i-IFG, the indices of insulin secretion were negatively correlated with the log-transformed TG and TG/HDL-C ratio. In both the subjects with i-IGT, multivariate linear regression analyses revealed that DI was positively correlated with HDL-C and negatively with log-transformed TG and TG/HDL-C ratio. On the other hand, in subjects with NGT, there was no association between insulin secretion and lipid profiles.ConclusionThese results revealed that serum TG and HDL-C levels have different impacts on early-phase insulin secretion on the basis of their glucose tolerance status.

  19. Reading Attitude as a Mediator between Contextual Factors and Reading Behavior

    Science.gov (United States)

    Lim, Hyo Jin; Bong, Mimi; Woo, Yeon-Kyung

    2015-01-01

    Background: Among the factors known to influence reading development and performance, attitude toward reading is shown to be particularly critical for developing learners. Reading attitude (McKenna, 1994; McKenna et al., 1995) enhances independent reading, levels of engagement in classroom reading activities, and the amount and variety of topics…

  20. The Contributions of Oral and Silent Reading Fluency to Reading Comprehension

    Science.gov (United States)

    Price, Katherine W.; Meisinger, Elizabeth B.; Louwerse, Max M.; D'Mello, Sidney

    2016-01-01

    Silent reading fluency has received limited attention in the school-based literatures across the past decade. We fill this gap by examining both oral and silent reading fluency and their relation to overall abilities in reading comprehension in fourth-grade students. Lower-level reading skills (word reading, rapid automatic naming) and vocabulary…

  1. Teaching Reading in High School: Improving Reading in Content Areas. Third Edition.

    Science.gov (United States)

    Karlin, Robert

    Designed for prospective and practicing secondary school teachers, this volume examines several aspects of reading in the content areas: the general reading problem in high schools, the development of programs for reading in specific subject areas, the psychology of reading instruction in the content areas, the improvement of diagnostic teaching,…

  2. IURead: a new computer-based reading test.

    Science.gov (United States)

    Xu, Renfeng; Bradley, Arthur

    2015-09-01

    To develop a computer-based single sentence reading test especially designed for clinical research enabling multiple repeat trials without reusing the same sentences. We initially developed 422 sentences, with an average of 60 characters and 12 words. Presentation controls were improved by employing computer-based testing and the oral reading was recorded by visual inspection of digital audio recordings. Variability in reading speed of normally sighted adults between sentences, between charts, between subjects, between formats, and between display devices was quantified. The impact of display size and pixel resolution on test geometry was assessed, and the impact of reduced retinal image quality and retinal illuminance were compared for reading and standard letter acuities. Eleven visually normal subjects (age: 18-60 years) participated in this study. Stopwatch timing of sentences reliably underestimated reading times by about 0.3 s, and exhibited coefficients of repeatability 17 times larger than those estimated from visual inspection of digital recordings. A slight relaxing of the lexical content constraints had no effect on reading speed; neither did sentence format (single vs three lines) or display size or distance. Within subject standard deviations of reading speed for different sentences were small (between 6% and 9% of the mean speed) requiring only small samples sizes to achieve typical statistical reliability and power when comparing conditions within individual subjects. The greater variability associated with stopwatch timing necessitates larger sample sizes. As defocus and light level were varied, reading acuity and standard letter acuity were highly correlated (r(2)  = 0.99), and reading acuity was slightly better. A computer-based IURead reading test provides a useful reading speed and reading acuity tool for clinical research involving multiple conditions and repeat testing of individual subjects. Ready to use IURead files for use with a

  3. Effect of ingestion of raw garlic on serum cholesterol level, clotting time and fibrinolytic activity in normal subjects.

    Directory of Open Access Journals (Sweden)

    Gadkari J

    1991-07-01

    Full Text Available The effect of raw garlic on serum cholesterol, fibrinolytic activity and clotting time was studied in 50 medical students of the age group of 17 to 22 years before and after feeding raw garlic. All pre-experimental values ranged within normal limits. The volunteers were then divided into experimental and control groups. The subjects of the experimental group were given 10 gm of raw garlic daily after breakfast for two months. Fasting blood samples of all the subjects were investigated after two months. In the control group, there was no significant change in any of the above parameters. In the experimental group, there was a significant decrease in serum cholesterol and an increase in clotting time and fibrinolytic activity. Hence, garlic may be an useful agent in prevention of thromboembolic phenomenon.

  4. Using Anticipatory Reading Guides to Improve Elementary Students’ Comprehension

    Directory of Open Access Journals (Sweden)

    Evan Ortlieb

    2013-07-01

    Full Text Available One of the greatest challenges of an elementary school teacher is equipping students with comprehension strategies that transfer to all content areas. With stable levels of reading achievement over the last two decades in the United States, it is necessary that further research be conducted on methods of increasing students’ comprehension proficiencies. This experimental research study explores the use of an anticipatory reading guide with third grade struggling readers across multiple subject areas. Findings indicate that the experimental treatment group outperformed the control group by a statistically significant rate on both reading and content area measures, indicating that when struggling readers practice and use strategies to explicitly think what will be asked of them after reading the passage they perform at higher levels.

  5. Comparison of subjective symptoms associated with exposure to low levels of formaldehyde between students enrolled and not enrolled in a gross anatomy course.

    Science.gov (United States)

    Mori, Mihoko; Matsumoto, Yuuki; Kushino, Nanae; Morimatsu, Yoshitaka; Hoshiko, Michiko; Saga, Tsuyoshi; Yamaki, Koh-ichi; Ishitake, Tatsuya

    2016-01-01

    This study aimed to evaluate students' subjective symptoms associated with exposure to low levels of formaldehyde (FA) during a gross anatomy course and to survey how the risk of subjective symptoms was affected by exposure to FA. We conducted three questionnaire surveys of 125 students enrolled in an anatomy course (FA exposure group) and 124 students not enrolled in the course (FA nonexposure group) before, during, and 6 months after the course. The questionnaire included questions inquiring about subjective symptoms, sex, age, and allergies. We analyzed differences in the prevalence of subjective symptoms in distinct survey periods. Furthermore, we analyzed the relationship between the subjective symptoms and exposure to FA after adjusting for allergy, sex, and age using multiple logistic regression analysis. The prevalence of some of the ocular, nasal, and nonspecific symptoms in the FA exposure group was low before the course, increased during the course and decreased 6 months after the course. A significant positive relationship was observed between exposure to FA and some symptoms after adjusting for allergy, sex, and age. We identified some concrete symptoms associated with exposure to FA. We suggest that the exposure to low levels of FA influences students' subjective symptoms.

  6. Strategies for Improving Reading Skills among ELL College Students

    Science.gov (United States)

    Lei, Simon A.; Berger, Adam M.; Allen, Brigita M.; Plummer, Chad V.; Rosenberg, Worka

    2010-01-01

    In order to successfully complete any college-level courses, English Language Learner (ELL) students must be able to read and comprehend a large volume of academic information. However, many instructors are completely overwhelmed in teaching their respective subject areas and are academically unprepared to teach ELL students appropriate reading…

  7. A short-term evaluation of the relationship between plasma ascorbic acid levels and periodontal disease in systemically healthy and type 2 diabetes mellitus subjects.

    Science.gov (United States)

    Gokhale, Neeraja H; Acharya, Anirudh B; Patil, Vidya S; Trivedi, Dheeraj J; Thakur, Srinath L

    2013-06-01

    Deficient ascorbic acid levels (AALs) and Type 2 diabetes mellitus (T2DM) are associated with periodontal disease. This study evaluated the relationship between plasma AAL and periodontitis in systemically healthy and T2DM subjects, which to the best of our knowledge is being reported for the first time. One hundred twenty subjects were categorized into four groups of 30 each as group 1: without periodontal disease; group 2: chronic gingivitis; group 3: chronic periodontitis, and group 4: chronic periodontitis and freshly diagnosed T2DM. Plaque index (PlI), sulcus bleeding index (SBI), and probing pocket depths (PPDs) were evaluated. Venous blood was evaluated for plasma AAL spectrophotometrically. Randomized subjects were subgrouped within groups 2-4, to receive either scaling and root planing (SRP) with dietary supplementation (450 mg) of ascorbic acid (AA) for two weeks or only SRP. After two weeks, the clinical parameters were reassessed. Tukey's multiple post hoc procedures and paired t test were used with the level of statistical significance adjusted to p ≤ .05. AAL plasma levels were significantly greater in group 1 than in group 2 (p = .0007) and in group 4 (p = .0003). A significant reduction in the SBI was seen in the subgroups that received dietary supplementation of vitamin C within group 2 (p = .0012) and group 4 (p = .036). Plasma AAL is below the normal range in systemically healthy subjects with gingivitis and diabetics with periodontitis. Dietary AA supplementation with SRP improves the SBI in subjects with gingivitis and diabetics with periodontitis.

  8. Pseudo-synesthesia through reading books with colored letters.

    Science.gov (United States)

    Colizoli, Olympia; Murre, Jaap M J; Rouw, Romke

    2012-01-01

    Synesthesia is a phenomenon where a stimulus produces consistent extraordinary subjective experiences. A relatively common type of synesthesia involves perception of color when viewing letters (e.g. the letter 'a' always appears as light blue). In this study, we examine whether traits typically regarded as markers of synesthesia can be acquired by simply reading in color. Non-synesthetes were given specially prepared colored books to read. A modified Stroop task was administered before and after reading. A perceptual crowding task was administered after reading. Reading one book (>49,000 words) was sufficient to induce effects regarded as behavioral markers for synesthesia. The results of the Stroop tasks indicate that it is possible to learn letter-color associations through reading in color (F(1, 14) = 5.85, p = .030). Furthermore, Stroop effects correlated with subjective reports about experiencing letters in color (r(13) = 0.51, p = .05). The frequency of viewing letters is related to the level of association as seen by the difference in the Stroop effect size between upper- and lower-case letters (t(14) = 2.79, p = .014) and in a subgroup of participants whose Stroop effects increased as they continued to read in color. Readers did not show significant performance advantages on the crowding task compared to controls. Acknowledging the many differences between trainees and synesthetes, results suggest that it may be possible to acquire a subset of synesthetic behavioral traits in adulthood through training. To our knowledge, this is the first evidence of acquiring letter-color associations through reading in color. Reading in color appears to be a promising avenue in which we may explore the differences and similarities between synesthetes and non-synesthetes. Additionally, reading in color is a plausible method for a long-term 'synesthetic' training program.

  9. Pseudo-Synesthesia through Reading Books with Colored Letters

    Science.gov (United States)

    Colizoli, Olympia; Murre, Jaap M. J.; Rouw, Romke

    2012-01-01

    Background Synesthesia is a phenomenon where a stimulus produces consistent extraordinary subjective experiences. A relatively common type of synesthesia involves perception of color when viewing letters (e.g. the letter ‘a’ always appears as light blue). In this study, we examine whether traits typically regarded as markers of synesthesia can be acquired by simply reading in color. Methodology/Principal Findings Non-synesthetes were given specially prepared colored books to read. A modified Stroop task was administered before and after reading. A perceptual crowding task was administered after reading. Reading one book (>49,000 words) was sufficient to induce effects regarded as behavioral markers for synesthesia. The results of the Stroop tasks indicate that it is possible to learn letter-color associations through reading in color (F(1, 14) = 5.85, p = .030). Furthermore, Stroop effects correlated with subjective reports about experiencing letters in color (r(13) = 0.51, p = .05). The frequency of viewing letters is related to the level of association as seen by the difference in the Stroop effect size between upper- and lower-case letters (t(14) = 2.79, p = .014) and in a subgroup of participants whose Stroop effects increased as they continued to read in color. Readers did not show significant performance advantages on the crowding task compared to controls. Acknowledging the many differences between trainees and synesthetes, results suggest that it may be possible to acquire a subset of synesthetic behavioral traits in adulthood through training. Conclusion/Significance To our knowledge, this is the first evidence of acquiring letter-color associations through reading in color. Reading in color appears to be a promising avenue in which we may explore the differences and similarities between synesthetes and non-synesthetes. Additionally, reading in color is a plausible method for a long-term ‘synesthetic’ training program. PMID

  10. Pseudo-synesthesia through reading books with colored letters.

    Directory of Open Access Journals (Sweden)

    Olympia Colizoli

    Full Text Available BACKGROUND: Synesthesia is a phenomenon where a stimulus produces consistent extraordinary subjective experiences. A relatively common type of synesthesia involves perception of color when viewing letters (e.g. the letter 'a' always appears as light blue. In this study, we examine whether traits typically regarded as markers of synesthesia can be acquired by simply reading in color. METHODOLOGY/PRINCIPAL FINDINGS: Non-synesthetes were given specially prepared colored books to read. A modified Stroop task was administered before and after reading. A perceptual crowding task was administered after reading. Reading one book (>49,000 words was sufficient to induce effects regarded as behavioral markers for synesthesia. The results of the Stroop tasks indicate that it is possible to learn letter-color associations through reading in color (F(1, 14 = 5.85, p = .030. Furthermore, Stroop effects correlated with subjective reports about experiencing letters in color (r(13 = 0.51, p = .05. The frequency of viewing letters is related to the level of association as seen by the difference in the Stroop effect size between upper- and lower-case letters (t(14 = 2.79, p = .014 and in a subgroup of participants whose Stroop effects increased as they continued to read in color. Readers did not show significant performance advantages on the crowding task compared to controls. Acknowledging the many differences between trainees and synesthetes, results suggest that it may be possible to acquire a subset of synesthetic behavioral traits in adulthood through training. CONCLUSION/SIGNIFICANCE: To our knowledge, this is the first evidence of acquiring letter-color associations through reading in color. Reading in color appears to be a promising avenue in which we may explore the differences and similarities between synesthetes and non-synesthetes. Additionally, reading in color is a plausible method for a long-term 'synesthetic' training program.

  11. Ghrelin system in alcohol-dependent subjects: role of plasma ghrelin levels in alcohol drinking and craving

    OpenAIRE

    Leggio, Lorenzo; Ferrulli, Anna; Cardone, Silvia; Nesci, Antonio; Miceli, Antonio; Malandrino, Noemi; Capristo, Esmeralda; Canestrelli, Benedetta; Monteleone, Palmiero; Kenna, George A.; Swift, Robert M.; Addolorato, Giovanni

    2011-01-01

    Animal studies suggest that the gut-brain peptide ghrelin plays an important role in the neurobiology of alcohol dependence (AD). Human studies show an effect of alcohol on ghrelin levels and a correlation between ghrelin levels and alcohol craving in alcoholics.

  12. The Relationship between Phonological Features in Oral Reading and Reading Comprehension of Black West Indians.

    Science.gov (United States)

    Sundre, Donna; Karlin, Andrea

    A study investigated the relationship between phonological features in the oral reading of black West Indians and their reading comprehension. Subjects were 54 college students at the College of the Virgin Islands, St. Thomas. Each subject was recorded reading two passages and completed two cloze tests. The tapes then were analyzed for nine…

  13. Alcohol Levels Do Not Accurately Predict Physical or Mental Impairment in Ethanol-Tolerant Subjects: Relevance to Emergency Medicine and Dram Shop Laws

    OpenAIRE

    Roberts, James R.; Dollard, Denis

    2010-01-01

    The human body and the central nervous system can develop tremendous tolerance to ethanol. Mental and physical dysfunctions from ethanol, in an alcohol-tolerant individual, do not consistently correlate with ethanol levels traditionally used to define intoxication, or even lethality, in a nontolerant subject. Attempting to relate observed signs of alcohol intoxication or impairment, or to evaluate sobriety, by quantifying blood alcohol levels can be misleading, if not impossible. We report a ...

  14. Do I really feel it? The contributions of subjective fluency and compatibility in low-level effects on aesthetic appreciation.

    Science.gov (United States)

    Forster, Michael; Fabi, Wolfgang; Leder, Helmut

    2015-01-01

    The causes for the liking of objects are multifaceted. According to the processing fluency account, the ease with which an object is processed leads to a subjective feeling of fluency. This subjective feeling is then interpreted as a positive reaction toward the object resulting higher liking. However, evidence regarding the processes underlying this relation is scarce. To show that the subjective feeling can indeed be responsible for liking, we experimentally manipulated processing ease by providing false physiological feedback (varying skin conductance indicated varying feelings of fluency) and by varying presentation times between 100 and 400 ms while participants viewed line drawings of objects and rated them for liking. A first experiment showed that both false physiological feedback and presentation duration influenced liking. Stimuli primed with a (fake) visualization of a physiological correlate of high ease of processing were liked more than stimuli primed with a low ease of processing. Liking ratings in a no-feedback condition fell between the high and low feedback conditions. To explore possible compatibility effects of coupling visual feedback to the fluency interpretation, in a second experiment we reversed the feedback interpretation-visualization of high skin conductance now indicated low ease of processing. The results show a similar pattern, though the effect was subtler. This indicates that when the coupling of feedback to fluency is less apparent or less compatible, the feeling is less strongly linked to liking. Our results support the claim that variations in the feeling of fluency affect the appreciation of objects in terms of liking. Together, the experiments suggest the contributions of processing ease as well as compatibility to the experience of liking.

  15. Robustness of parameter and standard error estimates against ignoring a contextual effect of a subject level covariate in cluster randomized trials

    NARCIS (Netherlands)

    Korendijk, E.J.H.; Hox, J.; Moerbeek, M.

    2011-01-01

    In experimental research, it is not uncommon to assign clusters to conditions.When analysing the data of such cluster-randomized trials, a multilevel analysis should be applied in order to take into account the dependency of firstlevel units (i.e., subjects) within a second-level unit (i.e., a

  16. Reduction in 24-Hour Plasma Testosterone Levels in Subjects Who Showered 15 or 30 Minutes After Application of Testosterone Gel

    NARCIS (Netherlands)

    de Ronde, W.; Vogel, S.; Bui, H.N.; Heijboer, A.C.

    2011-01-01

    Study Objective. To investigate whether showering, to prevent the involuntary transfer of testosterone to others through skin contact, either 15 or 30 minutes after application of testosterone gel would significantly affect plasma testosterone levels. Design. Prospective 3-way crossover trial.

  17. Elevated leptin levels in subjects with familial combined hyperlipidemia are associated with the increased risk for CVD.

    NARCIS (Netherlands)

    Vleuten, G.M. van der; Veerkamp, M.J.; Tits, L.J.H. van; Toenhake, H.; Heijer, M. den; Stalenhoef, A.F.H.; Graaf, J. de

    2005-01-01

    Familial combined hyperlipidemia (FCH) is characterized by hypercholesterolemia and/or hypertriglyceridemia and is associated with premature cardiovascular disease (CVD). Other features of FCH are obesity and insulin resistance. Serum leptin levels have been associated with obesity, insulin

  18. Definition of reference ranges for free T4, TSH, and thyroglobulin levels in healthy subjects of the Jaén Health District.

    Science.gov (United States)

    Olmedo Carrillo, Pablo; Santiago Fernández, Piedad; García Fuentes, Eduardo; Ureña Fernández, Tomás; Gutiérrez Alcántara, Carmen; Sánchez-Malo, Carolina; Gassó Campos, Manuela; Martínez Ramírez, María José

    2017-10-01

    The treatment guidelines for thyroid dysfunction recommend defining reference ranges for thyroid hormones in each area through assessment of local population data considering the iodine nutritional status. The aim of this study was to define the reference ranges of free thyroxine (FT4), TSH, and thyroglobulin levels in a general population from Jaen, an area of southern Spain with an adequate iodine nutritional status, and whether they were associated with urinary iodine levels. A cross-sectional study was conducted in 1,003 subjects of the general population of the Jaen Health District. Levels of urinary iodine, FT4, TSH, thyroglobulin, and thyroid peroxidase (TPO) antibodies were measured according to age and sex. Median and mean urinary iodine levels were 110.59μg/L and 130.11μg/L respectively. Median TSH level was 1.83μIU/mL (p2.5=0.56μIU/mL, p97.5=4.66μIU/mL). Median FT4 level was 0.84ng/dL (p2.5=0.62ng/dL, p97.5=1.18ng/dL). TPO antibodies were detected in 5.7% of subjects. There was no correlation between urinary iodine levels and FT4, TSH or TPO antibodies. Subjects with positive TPO antibodies had higher TSH levels (3.34μIU/L versus 2.14μIU/mL, P=.001; odds ratio=2.42). Urinary iodine levels in Jaen are optimal according to World Health Organization standards. Reference ranges of FT4, TSH, and thyroglobulin do not differ from those reported in the literature and are no associated to urinary iodine levels. The prevalence of positive TPO antibodies was similar to that reported in other Spanish areas. Copyright © 2017 SEEN y SED. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory

    National Research Council Canada - National Science Library

    Teri Lawton; John Shelley-Tremblay

    2017-01-01

    ... (PATH to Reading neurotraining) acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed, reading fluency, and the executive control functions of attention and working memory...

  20. A Case for Improved Reading Instruction for Academic English Reading Proficiency

    Directory of Open Access Journals (Sweden)

    Glenn Ole Hellekjær

    2008-06-01

    Full Text Available This article presents a study of the academic reading proficiency in English of 217 senior level Norwegian upper secondary school students who upon graduation are considered qualified for higher education. Testing with an International English Language Testing System (IELTS Academic Reading Module revealed that two thirds of the 178 respondents with ordinary EFL courses did not achieve the equivalent of the IELTS Band 6 score minimum that is usually required for admission to British and Australian universities. In comparison, two thirds of a sample of 39 respondents with a single, sheltered Content and Language Integrated Learning (CLIL subject achieved a Band 6 score or better. Closer analysis indicates that the poor test scores can be attributed to weaknesses in current English as a Foreign Language (EFL instruction where reading is neglected, where students do not learn to adjust how they read to reading purpose, and where they do not learn how to handle unfamiliar words to avoid disrupting the reading process. The article ends with suggestions on how to improve EFL instruction, in Norway and elsewhere.

  1. L2 Japanese Learners' Responses to Translation, Speed Reading, and "Pleasure Reading" as a Form of Extensive Reading

    Science.gov (United States)

    Tabata-Sandom, Mitsue

    2017-01-01

    Fluency development instruction lacks in reading in Japanese as a foreign language instruction. This study examined how 34 upper-intermediate level learners of Japanese responded when they first experienced pleasure reading and speed reading. The participants also engaged in intensive reading, the main component of which was translation. Survey…

  2. Association between the Postprandial Glucose Levels and Arterial Stiffness Measured According to the Cardio-ankle Vascular Index in Non-diabetic Subjects.

    Science.gov (United States)

    Tsuboi, Atsuko; Ito, Chikako; Fujikawa, Rumi; Yamamoto, Hideya; Kihara, Yasuki

    2015-01-01

    Although a relationship between post-challenge hyperglycemia and arterial stiffness has been reported, the relationship between the postprandial glucose levels and cardio-ankle vascular index (CAVI) in non-diabetic subjects is not clear. This study thus evaluated the association between the postprandial glucose levels after a composite meal and the degree of arterial stiffness measured according to CAVI in non-diabetic subjects. The subjects included 1,291 individuals (655 men and 636 women; mean age, 48.6 years; range, 23-85 years) who underwent medical examinations, including blood tests and CAVI assessments, between October 2005 and April 2012. The 1-hour postprandial glucose levels were determined after a 600-kcal traditional Japanese meal. The CAVI values were significantly higher in the subjects with higher 1-hour postprandial glucose levels (≥140 mg/dL in men; ≥158 mg/dL in women). A simple regression analysis indicated that the CAVI values were significantly correlated with the 1-hour postprandial glucose levels in men (r=0.286, pblood pressure, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, 1-hour postprandial glucose, homeostatis model assessment of insulin resistance, estimated glemerular filtration rate, and high sensitive C-reactive protein, stepwise multiple regression analysis demonstrated that the 1-hour postprandial glucose level was an independent predictor associated with the CAVI in men (p=0.003) and older women 50 years of age or older (p=0.003). This study demonstrated that the 1-hour postprandial glucose levels are associated with increased CAVI values in non-diabetic men and older women 50 years of age or older.

  3. Upgrading short-read animal genome assemblies to chromosome level using comparative genomics and a universal probe set.

    Science.gov (United States)

    Damas, Joana; O'Connor, Rebecca; Farré, Marta; Lenis, Vasileios Panagiotis E; Martell, Henry J; Mandawala, Anjali; Fowler, Katie; Joseph, Sunitha; Swain, Martin T; Griffin, Darren K; Larkin, Denis M

    2017-05-01

    Most recent initiatives to sequence and assemble new species' genomes de novo fail to achieve the ultimate endpoint to produce contigs, each representing one whole chromosome. Even the best-assembled genomes (using contemporary technologies) consist of subchromosomal-sized scaffolds. To circumvent this problem, we developed a novel approach that combines computational algorithms to merge scaffolds into chromosomal fragments, PCR-based scaffold verification, and physical mapping to chromosomes. Multigenome-alignment-guided probe selection led to the development of a set of universal avian BAC clones that permit rapid anchoring of multiple scaffolds to chromosomes on all avian genomes. As proof of principle, we assembled genomes of the pigeon (Columbia livia) and peregrine falcon (Falco peregrinus) to chromosome levels comparable, in continuity, to avian reference genomes. Both species are of interest for breeding, cultural, food, and/or environmental reasons. Pigeon has a typical avian karyotype (2n = 80), while falcon (2n = 50) is highly rearranged compared to the avian ancestor. By using chromosome breakpoint data, we established that avian interchromosomal breakpoints appear in the regions of low density of conserved noncoding elements (CNEs) and that the chromosomal fission sites are further limited to long CNE "deserts." This corresponds with fission being the rarest type of rearrangement in avian genome evolution. High-throughput multiple hybridization and rapid capture strategies using the current BAC set provide the basis for assembling numerous avian (and possibly other reptilian) species, while the overall strategy for scaffold assembly and mapping provides the basis for an approach that (provided metaphases can be generated) could be applied to any animal genome. © 2017 Damas et al.; Published by Cold Spring Harbor Laboratory Press.

  4. Effect of Training Exercise on Urinary Brain-derived Neurotrophic Factor Levels and Cognitive Performances in Overweight and Obese Subjects.

    Science.gov (United States)

    Russo, Angelo; Buratta, Livia; Pippi, Roberto; Aiello, Cristina; Ranucci, Claudia; Reginato, Elisa; Santangelo, Valerio; DeFeo, Pierpaolo; Mazzeschi, Claudia

    2017-02-01

    Exercise-mediated, brain-derived neurotrophic factor induction benefits health and cognitive functions. The multifaceted interplay between physical activity, urinary brain-derived neurotrophic factor levels and cognitive functioning has been largely neglected in previous literature. In this pilot study, two bouts of training exercise (65% and 70% of heart rate reserve) influenced urinary brain-derived neurotrophic factor levels and cognitive performances in 12 overweight and obese participants. Percent heart rate reserve, expenditure energy, brain-derived neurotrophic factor urinary levels and cognitive performances were measured before and after the exercise. No significant variations in energy expenditure were observed, while differences of heart rate reserve between two groups were maintained. Both bouts of training exercise induced a similar reduction in urinary brain-derived neurotrophic factor levels. Only visuo-spatial working memory capacity at 65% of heart rate reserve showed a significant increase. These findings indicate a consistent effect of training exercise on urinary brain-derived neurotrophic factor levels and cognitive factors in overweight and obese participants.

  5. Basic conditions for radioimmunoassay of erythropoietin, and plasma levels of erythropoietin in normal subjects and anemic patients

    Energy Technology Data Exchange (ETDEWEB)

    Mizoguchi, Hideaki; Ohta, Kazuo; Suzuki, Toshiaki; Murakami, Akihiko; Ueda, Masatsugu; Sasaki, Ryuzou; Chiba, Hideo

    1987-02-01

    We have developed a specific and sensitive radioimmunoassay for erythropoietin. The sensitivity of our assay is 0.5 mU or 5 mU/ml and is sufficient to detect normal plasma erythropoietin levels. The mean plasma erythropoietin titer of normal Japanese with our radioimmunoassay was found to be 21.9 +- 12.0 mU/ml (n = 199). The validity of the method was further confirmed by the observations that the plasma erythropoietin titers were inversely related to hemoglobin levels in patients with nonuremic anemias, lower in uremic patients than in patients with nonuremic anemias with similar hemoglobin levels, markedly elevated in patients with aplastic anemia and pure red cell aplasia, and in a low normal range in patients with polycythemia vera.

  6. Allergen-induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Subjects with Asthma.

    Science.gov (United States)

    Chen, Ruchong; Smith, Steven G; Salter, Brittany; El-Gammal, Amani; Oliveria, John Paul; Obminski, Caitlin; Watson, Rick; O'Byrne, Paul M; Gauvreau, Gail M; Sehmi, Roma

    2017-09-15

    Group 2 innate lymphoid cells (ILC2), a major source of type 2 cytokines, initiate eosinophilic inflammatory responses in murine models of asthma. To investigate the role of ILC2 in allergen-induced airway eosinophilic responses in subjects with atopy and asthma. Using a diluent-controlled allergen challenge crossover study, where all subjects (n = 10) developed allergen-induced early and late responses, airway eosinophilia, and increased methacholine airway responsiveness, bone marrow, blood, and sputum samples were collected before and after inhalation challenge. ILC2 (lin - FcεRI - CD45 + CD127 + ST2 + ) and CD4 + T lymphocytes were enumerated by flow cytometry, as well as intracellular IL-5 and IL-13 expression. Steroid sensitivity of ILC2 and CD4 + T cells was investigated in vitro. A significant increase in total, IL-5 + , IL-13 + , and CRTH2 + ILC2 was found in sputum, 24 hours after allergen, coincident with a significant decrease in blood ILC2. Total, IL-5 + , and IL-13 + , but not CRTH2 + , CD4 + T cells significantly increased at 24 and 48 hours after allergen in sputum. In blood and bone marrow, only CD4 + cells demonstrated increased activation after allergen. Airway eosinophilia correlated with IL-5 + ILC2 at all time points and allergen-induced changes in IL-5 + CD4 + cells at 48 hours after allergen. Dexamethasone significantly attenuated IL-2- and IL-33-stimulated IL-5 and IL-13 production by both cell types. Innate and adaptive immune cells are increased in the airways associated with allergic asthmatic responses. Total and type 2 cytokine-positive ILC2 are increased only within the airways, whereas CD4 + T lymphocytes demonstrated local and systemic increases. Steroid sensitivity of both cells may explain effectiveness of this therapy in those with mild asthma.

  7. The relationship between serum asymmetric dimethylarginine levels and subjective sleep quality in normotensive patients with type 2 diabetes mellitus.

    Science.gov (United States)

    Aribas, Alpay; Kayrak, Mehmet; Tekinalp, Mehmet; Akilli, Hakan; Alibasic, Hayrudin; Yildirim, Serkan; Gunduz, Mehmet; Taner, Alpaslan; Unlu, Ali

    2015-05-01

    Poor sleep quality (SQ) is associated with increased cardiovascular mortality and morbidity. Additionally, asymmetric dimethylarginine (ADMA) is an independent predictor of cardiovascular mortality and morbidity. However, no sufficient data regarding the relationship between ADMA levels and SQ have been reported. The goal of the current study was to evaluate the association between SQ and ADMA levels in normotensive patients with type 2 diabetes mellitus. The study participants consisted of 78 normotensive type 2 diabetics. The SQ of all participants was assessed using the Pittsburgh Sleep Quality Index (PSQI). Patients with a global PSQI score > 5 were defined as "poor sleepers." Factors associated with poor SQ were analyzed using a multiple regression model. Serum ADMA levels were measured using high performance liquid chromatography. The median ADMA levels of the poor sleepers were increased compared with patients defined as good sleepers (5.5 [4.2 to 6.6] vs. 4.4 [2.9 to 5.4], p poor sleepers (p sleep latency (p sleep efficiency (p = 0.01). Logistic regression analysis showed that ADMA levels (odds ratio [OR], 1.68; 95% confidence interval [CI], 1.16 to 2.44; p = 0.01) and body mass index (OR, 1.15; 95% CI, 1.01 to 1.31; p = 0.04) were associated with poor SQ independently of glomerular filtration rate, sex, age, duration of diabetes, hemoglobin A1c, total cholesterol, and systolic blood pressure. Self-reported SQ was independently associated with ADMA levels in normotensive patients with diabetes mellitus.

  8. Thyrotropin levels are associated with chronic kidney disease among healthy subjects in cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

    Science.gov (United States)

    Peixoto de Miranda, Érique José F; Bittencourt, Márcio Sommer; Goulart, Alessandra C; Santos, Itamar S; de Oliveira Titan, Silvia Maria; Ladeira, Roberto Marini; Barreto, Sandhi Maria; Lotufo, Paulo A; Benseñor, Isabela Judith Martins

    2017-12-01

    Few studies have evaluated a possible relationship between thyrotropin levels and glomerular filtration rate (GFR) and albumin/creatinine ratio in euthyroid subjects. We aimed to analyze this association using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Cross-sectionally, we included subjects with normal thyroid function and with subclinical hypothyroidism (SCH). We excluded individuals using medications that affect thyroid function. Linear and logistic regression models evaluated GFR estimated by Chronic Kidney Disease Epidemiology Collaboration (CKD-Epi) and albuminuria/creatinine ratio as dependent variables and thyrotropin quartiles in individuals with euthyroidism and SCH as independent variables, adjusted for demographical characteristics and diseases related to CKD. We included 13,193 subjects with a median age of 51 years [interquartile range, (IQR): 45-58], 6840 (51.8%) women, 12,416 (94.1%) euthyroid, and 777 (5.9%) with SCH. SCH subjects were characterized by higher age, triglycerides, frequency of white race, cardiovascular disease, CKD, and former smokers. In adjusted models, log-transformed TSH in euthyroid subjects was inversely and strongly associated with CKD (β = -2.181, 95% CI -2.714 to -1.648), P < 0.0001 for glomerular filtration rate and 4.528 (1.190-7.865) for albuminuria/creatinine ratio. Multivariate logistic models for euthyroid subjects showed an OR of 1.45 (95% CI 1.15-1.83) for GFR and of 1.95 (95% CI 1.08-3.54) for albuminuria/creatinine ratio in the fourth quartile of TSH using the first as the reference. Thyrotropin levels are independently associated with CKD in euthyroid subjects.

  9. Vitamin B-6 vitamer levels in plasma and related symptoms in hemodialysis subjects taking low- and high-dose renal multivitamin supplements.

    Science.gov (United States)

    Clement, Louise; Boylan, Mallory; Miller, Virginia; Driskell, Judy; Giraud, David; Subih, Hadil

    2012-04-01

    The purpose of this study was to evaluate the B-6 vitamers in plasma and related symptoms in hemodialysis subjects taking high- or low-dose vitamins. A total of 24 hemodialysis (HD) subjects were divided into two groups. Twelve subjects received a high-dose vitamin supplement [50 mg pyridoxine hydrochloride (PN-HCl) /tablet] and 12 received a low-dose vitamin supplements containing (10 mg PN-HCl/tablet) for 6+ months. Plasma B-6 vitamers were analyzed using HPLC. Other data were obtained from subjects' medical records. Subjects were assessed for vitamin B-6 related symptoms. Cluster analysis was used to form symptom groups. Student t-tests and analysis of variance were used to determine differences (p < 0.05) in group means. The mean ± SD plasma B-6 vitamer and 4-pyridoxic acid concentrations (nmol/L) were as follows in the 10-mg and 50-mg PN-HCl groups, respectively: pyridoxal- 5'-phosphate (PLP) 10 ± 3 and 16 ± 8 (p = 0.04); pyridoxal (PL) 50 ± 96 and 68 ± 06; pyridoxine (PN) 26 ± 50 and 191 ± 107; and 4-pyridoxic acid (4-PA) 43 ± 64 and 99 ± 361. The cluster group with a significantly higher (p = 0.04) plasma 4-PA concentration of 167 ± 697 nmol/L reported more tingling hands, tachycardia, and diarrhea. Plasma PLP levels and symptoms related to B-6 in HD subjects are impacted by dose of PN-HCl.

  10. Sleep Deprivation in Young and Healthy Subjects Is More Sensitively Identified by Higher Frequencies of Electrodermal Activity than by Skin Conductance Level Evaluated in the Time Domain

    Directory of Open Access Journals (Sweden)

    Hugo F. Posada-Quintero

    2017-06-01

    Full Text Available We analyzed multiple measures of the autonomic nervous system (ANS based on electrodermal activity (EDA and heart rate variability (HRV for young healthy subjects undergoing 24-h sleep deprivation. In this study, we have utilized the error awareness test (EAT every 2 h (13 runs total, to evaluate the deterioration of performance. EAT consists of trials where the subject is presented words representing colors. Subjects are instructed to press a button (“Go” trials or withhold the response if the word presented and the color of the word mismatch (“Stroop No-Go” trial, or the screen is repeated (“Repeat No-Go” trials. We measured subjects' (N = 10 reaction time to the “Go” trials, and accuracy to the “Stroop No-Go” and “Repeat No-Go” trials. Simultaneously, changes in EDA and HRV indices were evaluated. Furthermore, the relationship between reactiveness and vigilance measures and indices of sympathetic control based on HRV were analyzed. We found the performance improved to a stable level from 6 through 16 h of deprivation, with a subsequently sustained impairment after 18 h. Indices of higher frequencies of EDA related more to vigilance measures, whereas lower frequencies index (skin conductance leve, SCL measured the reactiveness of the subject. We conclude that indices of EDA, including those of the higher frequencies, termed TVSymp, EDASymp, and NSSCRs, provide information to better understand the effect of sleep deprivation on subjects' autonomic response and performance.

  11. Evaluation of the use of salivary lead levels as a surrogate of blood lead or plasma lead levels in lead exposed subjects

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, Fernando [Universidade de Sao Paulo, Departamento de Analises Clinicas, Toxicologicas e Bromatologicas, Faculdade de Ciencias Farmaceuticas de Ribeirao Preto, Ribeirao Preto, SP (Brazil); Correa Rodrigues, Maria H.; Buzalaf, Maria R. [Universidade de Sao Paulo, Departamento de Ciencias Biologicas/Bioquimica, Faculdade de Odontologia de Bauru, Bauru, SP (Brazil); Krug, Francisco J. [Universidade de Sao Paulo, Centro de Energia Nuclear na Agricultura, Piracicaba, SP (Brazil); Gerlach, Raquel F. [Universidade de Sao Paulo, Departamento de Morfologia, Estomatologia e Fisiologia, Faculdade de Odontologia de Ribeirao Preto, Ribeirao Preto, SP (Brazil); Tanus-Santos, Jose E. [Universidade de Sao Paulo, Departamento de Farmacologia, Faculdade de Medicina de Ribeirao Preto, Ribeirao Preto, SP (Brazil)

    2006-10-15

    We conducted a study to evaluate the use of parotid salivary lead (Pb-saliva) levels as a surrogate of the blood lead (Pb-B) or plasma lead levels (Pb-P) to diagnose lead exposure. The relationship between these biomarkers was assessed in a lead exposed population. Pb-saliva and Pb-P were determined by inductively coupled plasma mass spectrometry, while in whole blood lead was determined by graphite furnace atomic absorption spectrometry. We studied 88 adults (31 men and 57 women) from 18 to 60 years old. Pb-saliva levels varied from 0.05 to 4.4 {mu}g/l, with a mean of 0.85 {mu}g/l. Blood lead levels varied from 32.0 to 428.0 {mu}g/l in men (mean 112.3 {mu}g/l) and from 25.0 to 263.0 {mu}g/l (mean 63.5 {mu}g/l) in women. Corresponding Pb-Ps were 0.02-2.50 {mu}g/l (mean 0.77 {mu}g/l) and 0.03-1.6 {mu}g/l (mean 0.42 {mu}g/l) in men and women, respectively. A weak correlation was found between Log Pb-saliva and Log Pb-B (r=0.277, P<0.008), and between Log Pb-saliva and Log Pb-P (r=0.280, P=0.006). The Pb-saliva/Pb-P ratio ranged from 0.20 to 18.0. Age or gender does not affect Pb-saliva levels or Pb-saliva/Pb-P ratio. Taken together, these results suggest that salivary lead may not be used as a biomarker to diagnose lead exposure nor as a surrogate of plasma lead levels at least for low to moderately lead exposed population. (orig.)

  12. Polymorphism rs1761667 in the CD36 Gene Is Associated to Changes in Fatty Acid Metabolism and Circulating Endocannabinoid Levels Distinctively in Normal Weight and Obese Subjects

    Directory of Open Access Journals (Sweden)

    Melania Melis

    2017-12-01

    Full Text Available The multifunctional CD36 scavenger receptor facilitates fatty acid (FA uptake and oxidation and it has been involved in the pathophysiology related to dysfunctional FA metabolism. The common variant in the CD36 gene, rs1761667 (A/G, whose allele A is characterized by a reduced protein expression, has been associated with taste sensitivity to and preference for fat. We therefore aimed at evaluating whether the CD36 polymorphism may influence fatty acid metabolism and endocannabinoid biosynthesis in normal weight (NW and obese (OB subjects. Red blood cell (RBC fatty acid composition, and plasma endocannabinoid levels were determined. In NW subjects with AA genotype was found a marked reduction of RBC saturated fatty acids and palmitic/linoleic ratio (PA/LA, considered as de novo lipogenesis (DNL biomarkers. Remarkably, to the reduction of DNL biomarkers corresponded an increase of omega-6 index, an indirect marker of the impact on fatty acid metabolism of dietary omega-6 fatty acids, endocannabinoid levels and a higher waist/hip ratio. The presence of the G allele was instead associated with increased endocannabinoid plasma levels and a trend for increased waist/hip ratio in obese subjects, even though exhibited decreased BMI with respect to those with AA genotype. These data indicate that the CD36 polymorphism, rs1761667, leads to a distinct metabolic pattern in NW and in OB subjects. Therefore, their determination may be crucial in developing personalized therapeutic strategies for ameliorating dyslipidemia and other metabolic disorders.

  13. Why should I read? - A cross-cultural investigation into adolescents' reading socialisation and reading attitude

    Science.gov (United States)

    Broeder, Peter; Stokmans, Mia

    2013-06-01

    While reading behaviour of adolescents is a frequent object of research, most studies in this field are restricted to a single country. This study investigates reading as a leisure-time activity across social groups from three regions differing in reading tradition as well as in the facilities available for reading. The authors analyse the reading behaviour of a total of 2,173 adolescents in the Netherlands, in Beijing (China), and in Cape Town (South Africa). Taking Icek Ajzen's Theory of Planned Behaviour as a starting point, the authors adjusted it to model the three most important determinants of reading behaviour, namely (1) reading attitude; (2) subjective norms (implicit and explicit social pressure to read); and (3) perceived behavioural control, which includes reading proficiency and appropriateness of the available books (book supply). While they found the adjusted model to fit the Dutch and Beijing situation quite well, it appeared to be inappropriate for the Cape Town situation. Despite considerable cultural and situational differences between the Netherlands and Beijing, the results show a similar pattern for these two environments. The most important determinants turn out to be: the hedonic reading attitude, the implicit norm of family and friends, the attractiveness of the available choice of books, and the perceived reading proficiency.

  14. Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects

    NARCIS (Netherlands)

    Bucci, L.; Yani, S.L.; Fabbri, C.; Bijlsma, A.Y.; Maier, A.B.; Meskers, C.G.; Narici, M.V.; Jones, D.A.; McPhee, J.S.; Seppet, E.; Gapeyeva, H.; Paasuke, M.; Sipila, S.; Kovanen, V.; Stenroth, L.; Musaro, A.; Hogrel, J.Y.; Barnouin, Y.; Butler-Browne, G.; Capri, M.; Franceschi, C.; Salvioli, S.

    2013-01-01

    It is known that adipose tissue mass increases with age, and that a number of hormones, collectively called adipokines, are produced by adipose tissue. For most of them it is not known whether their plasmatic levels change with age. Moreover, it is known that adipose tissue infiltration in skeletal

  15. Effects of cimetidine and ranitidine on interdigestive and postprandial lower esophageal sphincter pressures and plasma gastrin levels in normal subjects

    NARCIS (Netherlands)

    Smout, A. J.; Bogaard, J. W.; van Hattum, J.; Akkermans, L. M.

    1985-01-01

    The purpose of this study was to investigate the effects of cimetidine and ranitidine on human lower esophageal sphincter pressure (LESP) and plasma levels of gastrin in all phases of the interdigestive motor complex and after a test meal. In a random, double-blind manner, placebo, cimetidine (1.0

  16. The effects of motor rehabilitation training on clinical symptoms and serum BDNF levels in Parkinson's disease subjects.

    Science.gov (United States)

    Angelucci, Francesco; Piermaria, Jacopo; Gelfo, Francesca; Shofany, Jacob; Tramontano, Marco; Fiore, Marco; Caltagirone, Carlo; Peppe, Antonella

    2016-04-01

    Increasing evidence suggests that motor rehabilitation may delay Parkinson's disease (PD) progression. Moreover, parallel treatments in animals up-regulate brain-derived neurotrophic factor (BDNF). Thus, we investigated the effect of a motor rehabilitation protocol on PD symptoms and BDNF serum levels. Motor rehabilitation training consisted of a cycle of 20 days/month of physiotherapy divided in 3 daily sessions. Clinical data were collected at the beginning, at the end, and at 90 days follow-up. BDNF serum levels were detected by ELISA at 0, 7, 14, 21, 30, and 90 days. The follow-up period had a duration of 60 days (T30-T90). The results showed that at the end of the treatment (day 30), an improvement in extrapyramidal signs (UPDRS III; UPDRS III - Gait and Balance items), motor (6 Minute Walking Test), and daily living activities (UPDRS II; PDQ-39) was observed. BDNF levels were increased at day 7 as compared with baseline. After that, no changes in BDNF were observed during the treatment and in the successive follow-up. This study demonstrates that motor rehabilitation training is able to ameliorate PD symptoms and to increase temporarily BDNF serum levels. The latter effect may potentially contribute to the therapeutic action.

  17. Macro-level determinants of young people's subjective health and health inequalities : A multilevel analysis in 27 welfare states

    NARCIS (Netherlands)

    Rathmann, Katharina; Ottova, Veronika; Hurrelmann, Klaus; de Looze, Margarethe; Levin, Kate; Molcho, Michal; Elgar, Frank; Gabhainn, Saoirse Nic; van Dijk, Jitse P.; Richter, Matthias

    Objectives: Cross-national studies have rarely focused on young people. The aim of this study is to investigate whether macro-level determinants are associated with health and socioeconomic inequalities in young people's health. Study design: Data were collected from the Health Behaviour in

  18. Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects.

    NARCIS (Netherlands)

    Mensink, R.P.; Katan, M.B.

    1990-01-01

    BACKGROUND. Fatty acids that contain a trans double bond are consumed in large amounts as hydrogenated oils, but their effects on serum lipoprotein levels are unknown. METHODS. We placed 34 women (mean age, 26 years) and 25 men (mean age, 25 years) on three mixed natural diets of identical nutrient

  19. Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet.

    Science.gov (United States)

    Sebeková, K; Krajcoviová-Kudlácková, M; Schinzel, R; Faist, V; Klvanová, J; Heidland, A

    2001-12-01

    Evidence indicates that food-derived Maillard's reaction products are absorbed and yet can be detected in the circulation. We postulated that consumption of the heat-treated food by omnivores could be reflected by higher plasma levels of advanced glycation end products (AGEs) in comparison with vegetarians, who in cooking (by keeping away from meat) use lower temperatures and less time for heating. Plasma fluorescent AGEs (350/450 nm) and N(epsilon)-(carboxymethyl)lysine (CML, competitive ELISA) levels were investigated in 3 groups of healthy vegetarians (9 vegans-V, 19 lactoovo-vegetarians--VLO and 14 semi-vegetarians--VS) and compared with those of age-matched omnivores (O, n=19). Mean duration of vegetarian diet was V: 7.2 +/- 1.0,VLO: 8.2 +/- 0.8 and VS: 7.9 +/- 1.1 years. Both fluorescent AGE (O: 9.9 +/- 0.5; V: 10.8 +/- 0.7, LO: 13.1 +/- 0.8* and SV: 11.6 +/- 1.2 x 10(3) AU), and CML levels (O: 427.1 +/- 15.0,V: 514.8 +/- 24.6*, LO: 525.7 +/- 29.5**, SV: 492.6 +/- 18.0* ng/ml) were significantly lower in omnivores than in vegetarians. Plasma glucose, parameters of renal function (plasma concentration of creatinine and cystatin C, calculated glomerular filtration rate--GFR) as well as C-reactive protein levels were within the normal range and did not differ significantly between the groups. Thus, neither decline of kidney function nor inflammatory processes contributed to the rise in plasma AGEs. Enhanced plasma AGE levels in vegetarians in comparison to omnivores are herein presented for the first time. Mechanisms of AGE elevation and potential pathophysiological relevance of this finding are to be elucidated in prospective studies.

  20. From Expressive Reading to Rapid Reading: The Rise in Reading Rate During the Efficiency Movement (1910-1925)

    Science.gov (United States)

    Taylor, Laura A.

    2015-01-01

    Reading rate, a component of reading not closely attended to by educators and researchers prior to the 20th century, quickly became the subject of considerable research shortly after the turn of the century. This article uses historical content analysis to examine primary source documents from that period (1910-1925) to explore why reading rate…

  1. Changes of serum omentin-1 levels in normal subjects, type 2 diabetes and type 2 diabetes with overweight and obesity in Chinese adults.

    Science.gov (United States)

    Zhang, Qiang; Zhu, Lei; Zheng, Min; Fan, Chaohua; Li, Yunhao; Zhang, Dan; He, Yanming; Yang, Hongjie

    2014-07-01

    Omentin-1 has been identified as interesting novel adipokines that may modulate insulin action. Its exact biological function is unclear. The aim of this study is to assay the levels of serum omentin-1 in normal subjects and type 2 diabetes mellitus (T2DM) with normal weight, overweight and obesity and to analyze the relationship between serum omentin-1 levels with body mass index (BMI), waist to hip ratio (WHR), glycosylated hemoglobin (HbA1c), plasma glucose, insulin resistance index (HOMA-IR) and serum lipid levels. There are eighty newly diagnosed type 2 diabetes patients, thirty-five type 2 diabetes patients with normal weight, twenty-nine type 2 diabetes patients with overweight, sixteen type 2 diabetes patients with obesity, and forty healthy control subjects were enrolled in this study. The levels of plasma glucose at fasting and 2-hour postprandial blood glucose and fasting serum levels of insulin, omentin-1and HbA1c were measured. HOMA-IR was calculated. Serum omentin-1 levels were found to be significantly decreased in type 2 diabetes patients with normal weight (821.16 ± 312.50 ng/L), in type 2 diabetes patients with overweight (748.00±322.51 ng/L), and in type 2 diabetes patients with obesity (530.44±357.35 ng/L) compared with healthy control subjects (994.71±435.90 ng/L) at Pinsulin (FINS), fasting plasma glucose (FPG), 2-hour postprandial blood glucose (2HPG), triglycerides (TG), and positively correlated to high-density lipoprotein (HDL). BMI was independent related factor that influenced the levels of serum omentin-1. Decreased omentin-1 levels may contribute to the development of insulin resistance, T2DM and particularly to obesity in Chinese adults, however, its role in these diseases needs to be fully elucidated. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  2. Reading Comprehension Level and Development in Native and Language Minority Adolescent Low Achievers: Roles of Linguistic and Metacognitive Knowledge and Fluency

    NARCIS (Netherlands)

    M. Trapman; Dr. A.J.S. van Gelderen; J. Hulstijn; Dr E.J. van Schooten

    2016-01-01

    In a longitudinal design, we measured 50 low-achieving adolescents’ reading comprehension development from Grades 7 to 9. There were 24 native Dutch and 26 language minority students. In addition, we assessed the roles of (a) linguistic knowledge, (b) metacognitive knowledge, and (c) reading fluency

  3. Comparison of reading comprehension and working memory in hearing-impaired and normal-hearing children

    Directory of Open Access Journals (Sweden)

    Mohammad Rezaei

    2013-03-01

    Full Text Available Background and Aim: Reading is the most important human need for learning. In normal-hearing people working memory is a predictor of reading comprehension. In this study the relationship between working memory and reading comprehension skills was studied in hearing-impaired children, and then compared with the normal-hearing group.Methods: This was a descriptive-analytic study. The working memory and reading comprehension skills of 18 (8 male, 10 female sever hearing-impaired children in year five of exceptional schools were compared by means of a reading test with 18 hearing children as control group. The subjects in the control group were of the same gender and educational level of the sample group.Results: The children with hearing loss performed similarly to the normal-hearing children in tasks related to auditory-verbal memory of sounds (reverse, visual-verbal memory of letters, and visual-verbal memory of pictures. However, they showed lower levels of performance in reading comprehension (p<0.001. Moreover, no significant relationship was observed between working memory and reading comprehension skills.Conclusion: Findings indicated that children with hearing loss have a significant impairment in the reading comprehension skill. Impairment in language knowledge and vocabulary may be the main cause of poor reading comprehension in these children. In hearing-impaired children working memory is not a strong predictor of reading comprehension.

  4. Impact of UGT1A1 gene variants on total bilirubin levels in Gilbert syndrome patients and in healthy subjects.

    Science.gov (United States)

    Rodrigues, Carina; Vieira, Emília; Santos, Rosário; de Carvalho, João; Santos-Silva, Alice; Costa, Elísio; Bronze-da-Rocha, Elsa

    2012-03-15

    The Gilbert syndrome is a benign form of unconjugated hyperbilirubinemia, mainly associated with alterations in UGT1A1 gene. This work investigated the effect of UGT1A1 variants on total bilirubin levels in Gilbert patients (n=45) and healthy controls (n=161). Total bilirubin levels were determined using a colorimetric method; molecular analysis of exons 1-5 and two UGT1A1 promoter regions were performed by direct sequencing and automatic analysis of fragments. Five in silico methods predicted the effect of new identified variants. A significant different allelic distribution, in Gilbert patients and in controls, was found for two promoter polymorphisms. Among patients, 82.2% were homozygous and 17.8% heterozygous for the c.-41_-40dupTA allele; in control group, 9.9% were homozygous and 43.5% heterozygous for this promoter variant, while 46.6% (n=75) presented the [A(TA)6TAA]. For the T>G transition at c.-3279 promoter region, in patients, 86.7% were homozygous and 13.3% heterozygous; in control group, 33.5% were homozygous for the wild type allele, 44.1% were heterozygous and 22.4% homozygous for the mutated allele. The two polymorphisms were in Hardy-Weinberg equilibrium in both groups. Sequencing of UGT1A1 coding region identified nine novel variants, five in patients and four in controls. In silico analysis of these amino acids replacements predicted four of them as benign and three as damaging. In conclusion, we demonstrated that total bilirubin levels are mainly determined by the TA duplication in the TATA-box promoter and by the c.-3279T>G variant. Alterations in the UGT1A1 coding region seem to be associated with increased bilirubin levels, and, therefore, with Gilbert syndrome. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Can elevated CO2 modify regeneration from seed banks of floating freshwater marshes subjected to rising sea-level?

    Science.gov (United States)

    Middleton, Beth A.; McKee, Karen L.

    2012-01-01

    Higher atmospheric concentrations of CO2 can offset the negative effects of flooding or salinity on plant species, but previous studies have focused on mature, rather than regenerating vegetation. This study examined how interacting environments of CO2, water regime, and salinity affect seed germination and seedling biomass of floating freshwater marshes in the Mississippi River Delta, which are dominated by C3 grasses, sedges, and forbs. Germination density and seedling growth of the dominant species depended on multifactor interactions of CO2 (385 and 720 μl l-1) with flooding (drained, +8-cm depth, +8-cm depth-gradual) and salinity (0, 6% seawater) levels. Of the three factors tested, salinity was the most important determinant of seedling response patterns. Species richness (total = 19) was insensitive to CO2. Our findings suggest that for freshwater marsh communities, seedling response to CO2 is species-specific and secondary to salinity and flooding effects. Elevated CO2 did not ameliorate flooding or salinity stress. Consequently, climate-related changes in sea level or human-caused alterations in hydrology may override atmospheric CO2 concentrations in driving shifts in this plant community. The results of this study suggest caution in making extrapolations from species-specific responses to community-level predictions without detailed attention to the nuances of multifactor responses.

  6. Comparison of high-sensitivity C-reactive protein and fetuin-A levels before and after treatment for subjects with subclinical hyperthyroidism.

    Science.gov (United States)

    Bilgir, Oktay; Bilgir, Ferda; Topcuoglu, Tuba; Calan, Mehmet; Calan, Ozlem

    2014-03-01

    This study was designed to show the effect of propylthiouracil treatment on sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels on subjects with subclinical hyperthyroidism. After checking sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels of 35 patients with subclinical hyperthyroidism, each was given 50 mg tablets of propylthiouracil three times daily. After 3 months, sCD40L, high-sensitivity C-reactive protein, and fetuin-A levels were then compared to the levels before treatment. Although high-sensitivity C-reactive protein and sCD40L levels were normal in the subclinical hyperthyroidism patients compared to the healthy controls, fetuin-A levels were statistically significantly higher (*p = 0.022). After treatment, fetuin-A levels of subclinical hyperthyroidism patients decreased statistically significantly compared to the levels before treatment (**p = 0.026). sCD40L and high-sensitivity C-reactive protein levels did not have a statistically significant difference compared to the control group and post-propylthiouracil treatment. In subclinical hyperthyroidism patients, high fetuin-A levels before propylthiouracil treatment and decreases in these levels after treatment in cases with subclinical hyperthyroidism indicated the possibility of preventing long-term cardiac complications with propylthiouracil treatment.

  7. A cognitive perspective on Singaporean primary school pupils' use of reading strategies in learning to read in English.

    Science.gov (United States)

    Zhang, Lawrence Jun; Gu, Peter Yongqi; Hu, Guangwei

    2008-06-01

    This study is conducted in Singapore, where learning to read in English is regarded as essential because it is offered as a First Language (L1) subject in the curriculum and is stipulated as the medium of instruction in the education system, and the mother tongues are offered as Second Language (L2) subjects, although the majority still learn English as an L2. The paper reports on the reading strategies used by Singaporean primary school pupils from a cognitive perspective, which is part of a larger study that aims to investigate these pupils' language learning strategies. The participants were 18 pupils from three neighbourhood primary schools, in grades Primary 4, 5 and 6. The data were collected from high- and low-proficiency pupils at each of the three grades in each school, who read two texts at each level. Grounded in an information-processing theory and based on successful experiences of scholars using think-aloud for data collection, we asked the pupils to read and report what they were thinking about while reading. The think-aloud protocols were recorded, transcribed verbatim, coded and analysed. The results suggest that participants' flexible and appropriate use of reading strategies varies according to language proficiency and grade level, with the high-proficiency group outperforming its lower-proficiency counterpart and the high-graders outnumbering the lower-graders in terms of the number of strategies that they used. These differences were also exemplified with qualitative findings from case studies. The use of reading strategies differs according to proficiency levels, and the quality of pupils' strategy-use patterns has more significant implications for understanding efficient reading among primary school pupils.

  8. Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study

    Directory of Open Access Journals (Sweden)

    Anne Huotari

    2010-01-01

    Full Text Available Depression is an independent risk factor for cardiovascular diseases and is associated with metabolic syndrome (MetS. Levels of plasminogen activator inhibitor-1 (PAI-1, an inhibitor of tissue-type and urokinase-type plasminogen activators, are associated with MetS. To clarify the role of PAI-1 in subjects with long-term adverse mental symptomatology (LMS; including depression and MetS, we measured circulating PAI-1 levels in controls (n=111, in subjects with MetS and free of mental symptoms (n=42, and in subjects with both MetS and long-term mental symptoms (n=70. PAI-1 increased linearly across the three groups in men. In logistic regression analysis, men with PAI-1 levels above the median had a 3.4-fold increased likelihood of suffering from the comorbidity of long-term adverse mental symptoms and MetS, while no such associations were detected in women. In conclusion, our results suggest that in men high PAI-1 levels are independently associated with long-term mental symptomatology.

  9. Levels of serum retinol binding protein 4 before and after non-surgical periodontal treatment in lean and obese subjects: an interventional study.

    Science.gov (United States)

    Martínez-Herrera, Mayte; Silvestre, Francisco Javier; Silvestre-Rangil, Javier; López-Domènech, Sandra; Bañuls, Celia; Rocha, Milagros

    2017-11-18

    We aimed to evaluate serum RBP4 levels before and after periodontal therapy in lean and obese subjects with chronic periodontitis (CP) in order to determine its possible association with periodontitis. This is an interventional study for which a total of 112 lean and 119 obese subjects were recruited. Patients with CP were evaluated before and after three months of non-surgical periodontal treatment. Periodontal, anthropometric, biochemical parameters and serum levels of TNFα, IL-6, hsCRP and RBP4 were assessed. Serum RBP4 levels were associated with an increased probability of periodontitis (OR= 1.60; 95% CI: 1.02-2.50), showing patients with CP to have higher RBP4 levels than those without CP in both lean and obese populations (3.35 vs 3.06 and 3.74 vs 3.21, respectively). Following periodontal treatment, RBP4 and TNFα decreased and all periodontal parameters improved to the same extent in both groups, except for number of teeth with probing depth (PD) ≥4 mm, which improved to a less extent in obese than in lean subjects. In the multivariable regression model, number of teeth with PD ≥4 mm was independently associated with RBP4 (β=0.192). RBP4 was associated with chronic periodontitis before and after non-surgical periodontal treatment. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  10. Does Computer Screen Color Affect Reading Rate?

    Science.gov (United States)

    Clausing, Carolyn S.; Schmitt, Dorren R.

    A study investigated differences in reading rate and comprehension scores of 8th grade students on a cloze reading exercise involving the reading of a cloze passage from 10 different modes of text presentation (8 different computer screen formats and 2 different paper formats). Subjects, 300 students in computer literacy classes from 7 schools in…

  11. Impact of bariatric surgery on apolipoprotein C-III levels and lipoprotein distribution in obese human subjects.

    Science.gov (United States)

    Maraninchi, Marie; Padilla, Nadège; Béliard, Sophie; Berthet, Bruno; Nogueira, Juan-Patricio; Dupont-Roussel, Jeanine; Mancini, Julien; Bégu-Le Corroller, Audrey; Dubois, Noémie; Grangeot, Rachel; Mattei, Catherine; Monclar, Marion; Calabrese, Anastasia; Guérin, Carole; Desmarchelier, Charles; Nicolay, Alain; Xiao, Changting; Borel, Patrick; Lewis, Gary F; Valéro, René

    Elevated apolipoprotein C-III (apoC-III) has been postulated to contribute to the atherogenic dyslipidemia seen in obesity and insulin-resistant states, mainly by impairing plasma triglyceride-rich lipoprotein (TRL) metabolism. Bariatric surgery is associated with improvements of several obesity-associated metabolic abnormalities, including a reduction in plasma triglycerides (TGs) and an increase in plasma high-density lipoprotein cholesterol (HDL-C). We investigated the specific effect of bariatric surgery on apoC-III concentrations in plasma, non-HDL, and HDL fractions in relation to lipid profile parameters evolution. A total of 132 obese subjects undergoing bariatric surgery, gastric bypass (n = 61) or sleeve gastrectomy (n = 71), were studied 1 month before surgery and 6 and 12 months after surgery. Plasma apoC-III, non-HDL-apoC-III, and HDL-apoC-III concentrations were markedly reduced after surgery and strongly associated with reduction in plasma TG. This decrease was accompanied by a redistribution of apoC-III from TRL to HDL fractions. In multivariate analysis, plasma apoC-III was the strongest predictor of TG reduction after surgery, and the increase of HDL-C was positively associated with plasma adiponectin and negatively with body mass index. Marked reduction of apoC-III and changes in its distribution between TRL and HDL consistent with a better lipid profile are achieved in obese patients after bariatric surgery. These apoC-III beneficial modifications may have implications in dyslipidemia improvement and contribute to cardiovascular risk reduction after surgery. Copyright © 2017 National Lipid Association. Published by Elsevier Inc. All rights reserved.

  12. C-type natriuretic peptide plasma levels are elevated in subjects with achondroplasia, hypochondroplasia, and thanatophoric dysplasia.

    Science.gov (United States)

    Olney, Robert C; Prickett, Timothy C R; Espiner, Eric A; Mackenzie, William G; Duker, Angela L; Ditro, Colleen; Zabel, Bernhard; Hasegawa, Tomonobu; Kitoh, Hiroshi; Aylsworth, Arthur S; Bober, Michael B

    2015-02-01

    C-type natriuretic peptide (CNP) is a crucial regulator of endochondral bone growth. In a previous report of a child with acromesomelic dysplasia, Maroteaux type (AMDM), caused by loss-of-function of the CNP receptor (natriuretic peptide receptor-B [NPR-B]), plasma levels of CNP were elevated. In vitro studies have shown that activation of the MAPK kinase (MEK)/ERK MAPK pathway causes functional inhibition of NPR-B. Achondroplasia, hypochondroplasia, and thanatophoric dysplasia are syndromes of short-limbed dwarfism caused by activating mutations of fibroblast growth factor receptor-3, which result in overactivation of the MEK/ERK MAPK pathway. The purpose of this study was to determine whether these syndromes exhibit evidence of CNP resistance as reflected by increases in plasma CNP and its amino-terminal propeptide (NTproCNP). This was a prospective, observational study. Participants were 63 children and 20 adults with achondroplasia, 6 children with hypochondroplasia, 2 children with thanatophoric dysplasia, and 4 children and 1 adult with AMDM. Plasma levels of CNP and NTproCNP were higher in children with achondroplasia with CNP SD scores (SDSs) of 1.0 (0.3-1.4) (median [interquartile range]) and NTproCNP SDSs of 1.4 (0.4-1.8; P achondroplasia (CNP SDSs of 1.5 [0.7-2.1] and NTproCNP SDSs of 0.5 [0.1-1.0], P < .005). In children with hypochondroplasia, CNP SDSs were 1.3 (0.7-1.5) (P = .08) and NTproCNP SDSs were 1.9 (1.8-2.3) (P < .05). In children with AMDM, CNP SDSs were 1.6 (1.4-3.3) and NTproCNP SDSs were 4.2 (2.7-6.2) (P < .01). In these skeletal dysplasias, elevated plasma levels of proCNP products suggest the presence of tissue resistance to CNP.

  13. Quantitative and qualitative carcass characteristics of feedlot ewes subjected to increasing levels of concentrate in the diet

    Directory of Open Access Journals (Sweden)

    R.A.S. Cacere

    2014-10-01

    Full Text Available The aim of this study was to evaluate the effect of increasing levels of concentrate on the quantitative and qualitative carcass characteristics of feedlot ewes. Twenty-four crossbred ewes were randomly distributed in four treatments: (1 diet with 20%; (2 40%; (3 60%; and (4 80% of concentrate. Animals were slaughtered when those receiving the diet with 80% of concentrate reached adult weight, at around 50kg LW. The data were analyzed by means of variance and regression analyses and correlations. The levels of concentrate increased live weight at slaughter linearly. Height at the withers and rump presented medium to high correlation (0.86. The correlation of loin eye area measured on the carcass and by ultrasound examination was 0.81, whereas for back fat thickness it was 0.85. The increase in the use of concentrate in the diets promotes heavier carcasses with better yields and fat cover. Some measures obtained in vivo presented high correlation with those measured on the carcass. The use of ultrasound can be a way to predict the in vivo loin eye area. The use of concentrate improves the meat quality in variables' color and appearance.

  14. Dynamic Response of Cable-Supported Façades Subjected to High-Level Air Blast Loads: Numerical Simulations and Mitigation Techniques

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    Claudio Amadio

    2012-01-01

    Full Text Available A glazing façade subjected to blast loads has a structural behaviour that strongly differs from the typical response of a glazing system subjected to ordinary loads. Consequently, sophisticated modelling techniques are required to identify correctly its criticalities. The paper investigates the behaviour of a cable-supported façade subjected to high-level blast loading. Nonlinear dynamic analyses are performed in ABAQUS/Explicit using a sophisticated FE-model (M01, calibrated to dynamic experimental and numerical results. The structural effects of the total design blast impulse, as well as only its positive phase, are analyzed. At the same time, the possible cracking of glass panels is taken into account, since this phenomenon could modify the response of the entire façade. Finally, deep investigations are dedicated to the bearing cables, since subjecting them to elevated axial forces and their collapse could compromise the integrity of the cladding wall. Based on results of previous studies, frictional devices differently applied at their ends are presented to improve the response of the façade under the impact of a high-level explosion. Structural effects of various solutions are highlighted through dynamic simulations. Single vertical devices, if appropriately calibrated, allow reducing significantly the axial forces in cables, and lightly the tensile stresses in glass panes.

  15. Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects

    DEFF Research Database (Denmark)

    Rasmussen, M H; Hvidberg, A; Juul, A

    1995-01-01

    In the present study, we 1) determined whether the impaired spontaneous 24-h GH secretion as well as the blunted GH response to provocative testing in obese subjects are persistent disorders or transient defects reversed with weight loss and 2) investigated 24-h urinary GH excretion and basal...... levels of insulin-like growth factor-I (IGF-I), IGF-binding protein-3 (IGFBP-3), as well as insulin in obese subjects before and after a massive weight loss. We studied 18 obese subjects (age, 26 +/- 1 yr; body mass index, 40.9 +/- 1.1 kg/m2); 18 normal age-, and sex-matched control subjects; and 9...... reduced weight obese subjects after a diet-induced average weight loss of 30.3 +/- 4.6 kg. Twenty-four-hour spontaneous GH secretion was estimated by obtaining 3240 integrated 20-min blood samples using a constant blood withdrawal technique and computerized algorithms. Body composition was determined...

  16. The Benefits of Graded Reading

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    Mustafa Albay

    2017-06-01

    Full Text Available Doing large amounts of extensive reading at suitable levels of understanding is a productive tool to increase reading rate, vocabulary, motivation, attitude and general language proficiency. The amount of vocabulary and grammar learners has determines their language proficiency. Extensive reading enables learners to attain competencies in language skills. Graded readers are essential materials for doing extensive reading. They are particularly designed to enable learners practice reading skills and provide an opportunity to reinforce known vocabulary. Through multiple exposures learners become familiar with grammatical structures and vocabulary. Moreover, learners experience how they function in texts and they are motivated to use the vocabulary and structures they have learnt in their communication. Graded readers motivate learners, help them gain reading fluency, enhance their vocabulary and grammar knowledge development. This article defines extensive reading, emphasizes its contributions to language proficiency development and finally stresses out the role of grader readers in language learning.

  17. Abnormal auditory mismatch response in tinnitus sufferers with high-frequency hearing loss is associated with subjective distress level

    Directory of Open Access Journals (Sweden)

    Berg Patrick

    2004-03-01

    Full Text Available Abstract Background Tinnitus is an auditory sensation frequently following hearing loss. After cochlear injury, deafferented neurons become sensitive to neighbouring intact edge-frequencies, guiding an enhanced central representation of these frequencies. As psychoacoustical data 123 indicate enhanced frequency discrimination ability for edge-frequencies that may be related to a reorganization within the auditory cortex, the aim of the present study was twofold: 1 to search for abnormal auditory mismatch responses in tinnitus sufferers and 2 relate these to subjective indicators of tinnitus. Results Using EEG-mismatch negativity, we demonstrate abnormalities (N = 15 in tinnitus sufferers that are specific to frequencies located at the audiometrically normal lesion-edge as compared to normal hearing controls (N = 15. Groups also differed with respect to the cortical locations of mismatch responsiveness. Sources in the 90–135 ms latency window were generated in more anterior brain regions in the tinnitus group. Both measures of abnormality correlated with emotional-cognitive distress related to tinnitus (r ~ .76. While these two physiological variables were uncorrelated in the control group, they were correlated in the tinnitus group (r = .72. Concerning relationships with parameters of hearing loss (depth and slope, slope turned out to be an important variable. Generally, the steeper the hearing loss is the less distress related to tinnitus was reported. The associations between slope and the relevant neurophysiological variables are in agreement with this finding. Conclusions The present study is the first to show near-to-complete separation of tinnitus sufferers from a normal hearing control group based on neurophysiological variables. The finding of lesion-edge specific effects and associations with slope of hearing loss corroborates the assumption that hearing loss is the basis for tinnitus development. It is likely that some central

  18. An investigation of Chinese university EFL learner’s foreign language reading anxiety, reading strategy use and reading comprehension performance

    OpenAIRE

    Zhongshe Lu; Meihua Liu

    2015-01-01

    The present study explored the interrelations between foreign language (FL) reading anxiety, FL reading strategy use and their interactive effect on FL reading comprehension performance at the tertiary level in China. Analyses of the survey data collected from 1702 university students yielded the following results: (a) Both Foreign Language Reading Anxiety Scale (FLRAS) and Foreign Language Reading Strategy Use Scale (FLRSUS) had important subcomponents, (b) more than half of the students gen...

  19. Copper and zinc level in biological samples from healthy subjects of vegetarian food habit in reference to community environment

    Energy Technology Data Exchange (ETDEWEB)

    Bhattacharya, R.D.; Patel, T.S.; Pandya, C.B.

    1985-04-01

    Many epidemiologists have found a correlation between copper and zinc in the community environment and diseases, such as myocardial and vascular pathologies, and diabetes. The purpose of this study was to investigate the total daily intake of these two metals in cooked food, drinking water and air and their respective levels in blood and urine. A chronobiological methodology has been adopted to establish the reference values of these two metals in biological samples. It has been observed that the daily intake of copper is within the recommended value, whereas its urinary excretion is high. The daily intake of zinc is below the recommended value and its urinary excretion is also high. Both the metals showed a temporal oscillation pattern in blood and urine. A possible chronic zinc deficiency has been anticipated in this particular ethnic group of vegetarian food habit.

  20. Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, improves apolipoprotein levels in non-diabetic subjects with insulin resistance

    DEFF Research Database (Denmark)

    Schuster, H.; Fagerberg, B.; Edwards, S.

    2008-01-01

    Aim: To determine the effects of the peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist tesaglitazar on serum levels of apolipoprotein (apo) A-I, apoB, and apoCIII in non-diabetic insulin-resistant subjects. Methods: This randomized, double-blind, multicentre, placebo...... associated with insulin resistance. (C) 2007 Elsevier Ireland Ltd. All rights reserved Udgivelsesdato: 2008/3...

  1. Basic Concepts of Reading Instruction

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    Gökhan ARI

    2017-12-01

    Full Text Available Reading act is performed by connected physiological, psychological and cognitive processes. The operations taking place in these processes are expected to continue for life by being developed with certain strategies. A lot of information is gained with reading skill in education life. Therefore, basic concepts that constitute reading education in teaching and improving reading are important for teachers. The aim of this study is to submit information compiled from the literature about reading education process and which basic concepts are used in reading education. While teaching reading from part to whole, from whole to part and interactional approaches are used. From part to whole approach is at the forefront. Then with interactional approach strategies, both code solving and making sense is improved. Teachers should know the characteristics of bouncing, stopping, turning back, and scanning movements of the eye both in code solving and making sense. The teacher should configure the teaching for the students to gain fluid reading elements by making use of reading out and reading silently. After reading act is acquired; good reader characteristics should be gained by improving asking questions, guessing, summarizing, interpretation skills in integrated readings. Reading skill is improved by studies on the text. Therefore, the students should come across texts that are suitable to their levels, textuality and readability criteria. The vocabulary of children should be improved in a planned way with text-based word and meaning studies. Fluid reading, making sense and interpretation skills of children should be pursued with different evaluation types. In the long term, work should be done to make reading a habit for them.

  2. Blood Pressure Is the Determinant for the Increased Risk for Intracranial Arterial Stenosis in Subjects with Elevated Glycated Hemoglobin Levels: The Kangbuk Samsung Health Study.

    Science.gov (United States)

    Oh, Hyung-Geun; Rhee, Eun-Jung

    2016-11-01

    Ischemic stroke is known to be an important vascular complication of diabetes. Intracranial arterial stenosis (ICAS) is considered as an important cause of stroke in Asians. We aimed to analyze the risk for ICAS assessed by transcranial Doppler (TCD) ultrasonography in different groups of young Korean subjects divided by glycated hemoglobin (HbA1c) levels. This study included 10,437 participants without history of cardiovascular diseases (81.3% men, mean age 43 years) from a health screening program, in whom TCD ultrasonography was used to detect greater than 50% ICAS based on criteria modified from the SONIA (Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis) trial. The subjects were divided into 3 groups according to HbA1c levels: HbA1c < 5.7%, 5.7 ≤ HbA1c < 6.5%, and HbA1c ≥ 6.5% or under medication for diabetes. Among the participants, 3.0% of the subjects had ICAS. The subjects with ICAS tended to have higher mean HbA1c level compared with those without ICAS (5.8 ± .8 versus 5.7 ± .6, P = .063). The proportion of subjects with ICAS significantly increased as the HbA1c increased from the first to the third group (2.8%, 3.0%, 4.6%, P for linear trend = .022). In logistic regression analysis with ICAS as the dependent variable, the group with HbA1c ≥ 6.5% showed significantly increased odds ratio for ICAS with subjects with HbA1c < 5.7% as the reference after adjustment for confounding variables (1.575, 95% confidence interval 1.056-2.347). However, this significance disappeared with inclusion of presence of hypertension in the model. The risk for ICAS assessed by TCD was increased in young Korean subjects with HbA1c ≥ 6.5%. However, this significance was attenuated after adjustment for presence of hypertension, suggesting the importance of hypertension in ICAS. Copyright © 2016 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  3. Changes in the activity levels of glutamine synthetase, glutaminase and glycogen synthetase in rats subjected to hypoxic stress

    Science.gov (United States)

    Vats, P.; Mukherjee, A. K.; Kumria, M. M. L.; Singh, S. N.; Patil, S. K. B.; Rangnathan, S.; Sridharan, K.

    Exposure to high altitude causes loss of body mass and alterations in metabolic processes, especially carbohydrate and protein metabolism. The present study was conducted to elucidate the role of glutamine synthetase, glutaminase and glycogen synthetase under conditions of chronic intermittent hypoxia. Four groups, each consisting of 12 male albino rats (Wistar strain), were exposed to a simulated altitude of 7620 m in a hypobaric chamber for 6 h per day for 1, 7, 14 and 21 days, respectively. Blood haemoglobin, blood glucose, protein levels in the liver, muscle and plasma, glycogen content, and glutaminase, glutamine synthetase and glycogen synthetase activities in liver and muscle were determined in all groups of exposed and in a group of unexposed animals. Food intake and changes in body mass were also monitored. There was a significant reduction in body mass (28-30%) in hypoxia-exposed groups as compared to controls, with a corresponding decrease in food intake. There was rise in blood haemoglobin and plasma protein in response to acclimatisation. Over a three-fold increase in liver glycogen content was observed following 1 day of hypoxic exposure (4.76+/-0.78 mg.g-1 wet tissue in normal unexposed rats; 15.82+/-2.30 mg.g-1 wet tissue in rats exposed to hypoxia for 1 day). This returned to normal in later stages of exposure. However, there was no change in glycogen synthetase activity except for a decrease in the 21-days hypoxia-exposed group. There was a slight increase in muscle glycogen content in the 1-day exposed group which declined significantly by 56.5, 50.6 and 42% following 7, 14, and 21 days of exposure, respectively. Muscle glycogen synthetase activity was also decreased following 21 days of exposure. There was an increase in glutaminase activity in the liver and muscle in the 7-, 14- and 21-day exposed groups. Glutamine synthetase activity was higher in the liver in 7- and 14-day exposed groups; this returned to normal following 21 days of exposure

  4. AP1000 Shield Building Dynamic Response for Different Water Levels of PCCWST Subjected to Seismic Loading considering FSI

    Directory of Open Access Journals (Sweden)

    Daogang Lu

    2015-01-01

    Full Text Available Huge water storage tank on the top of many buildings may affect the safety of the structure caused by fluid-structure interaction (FSI under the earthquake. AP1000 passive containment cooling system water storage tank (PCCWST placed at the top of shield building is a key component to ensure the safety of nuclear facilities. Under seismic loading, water will impact the wall of PCCWST, which may pose a threat to the integrity of the shield building. In the present study, an FE model of AP1000 shield building is built for the modal and transient seismic analysis considering the FSI. Six different water levels in PCCWST were discussed by comparing the modal frequency, seismic acceleration response, and von Mises stress distribution. The results show the maximum von Mises stress emerges at the joint of shield building roof and water around the air inlet. However, the maximum von Mises stress is below the yield strength of reinforced concrete. The results may provide a reference for design of the AP1000 and CAP1400 in the future.

  5. A relationship between vitamin D, parathyroid hormone, calcium levels and lactose intolerance in type 2 diabetic patients and healthy subjects.

    Science.gov (United States)

    Rana, SatyaVati; Morya, Rajesh Kumar; Malik, Aastha; Bhadada, Sanjay Kumar; Sachdeva, Naresh; Sharma, Gaurav

    2016-11-01

    Type 2 diabetes mellitus is chronic metabolic disorder. Common gastrointestinal symptoms in type 2 diabetic patients are flatulence, constipation and/or diarrhea. Reason for these may be lactose intolerance leading to change in vitamin D, Calcium and parathyroid hormone which further regulate bone mineralization. To measure lactose intolerance, vitamin D, calcium and parathyroid hormone in type 2 diabetic patients. 150 type 2 diabetic patients attending Endocrinology Clinic in PGI, Chandigarh and 150 age and sex matched healthy controls were enrolled. Lactose intolerance was measured using non-invasive lactose breath test. 25-hydroxyvitamin D (total) and Parathyroid hormone were measured in plasma using immunoassay. Serum calcium was measured using auto analyzer. T score was recorded from DXA scan for bone mineral density measurement. Lactose intolerance was observed significantly higher (pintolerant diabetic patients than lactose tolerant patients. Sixty seven percent (67%) of diabetic patients suffered from osteoporosis and 20% of controls. Eighty percent (80%) diabetic patients and 16% controls with osteoporosis suffered from lactose intolerance. From this study we can conclude that measurement of lactose intolerance using non-invasive lactose breath test is suggested for type 2 diabetic patients along with timely measurement of 25-OH vitamin D (total), calcium and parathyroid hormone levels. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Reading Habits and Attitudes of UMSKAL Undergraduates

    OpenAIRE

    Shameem Ahmed

    2016-01-01

    Effective reading is essential for success in acquiring a foreign language (Mikulecky 2008). Students have to read a wide range of textbooks and related materials at the tertiary level. Lack of adequate reading habit is, therefore, bound to impede students’ progress towards mastery of a foreign language. This study investigated reading habits and attitudes on reading of the undergraduate students attending ESL courses at a public university in Malaysia. For data collection, a 35 item question...

  7. Examining School-Level Reading and Math Proficiency Trends and Changes in Achievement Gaps for Grades 3-8 in Florida, Mississippi, and North Carolina. REL 2017-235

    Science.gov (United States)

    Herrera, Sarah; Zhou, Chengfu; Petscher, Yaacov

    2017-01-01

    The 2001 authorization of the No Child Left Behind Act and its standards and accountability requirements generated interest among state education agencies in Florida, Mississippi, and North Carolina, which are served by the Regional Educational Laboratory Southeast, in monitoring changes in student reading and math proficiency at the school level.…

  8. Omega-3 fatty acids status in human subjects estimated using a food frequency questionnaire and plasma phospholipids levels

    Directory of Open Access Journals (Sweden)

    Garneau Véronique

    2012-07-01

    Full Text Available Abstract Background Intakes of omega-3 (n-3 fatty acids (FA are associated with several health benefits. The aim of this study was to verify whether intakes of n-3 FA estimated from a food frequency questionnaire (FFQ correlate with n-3 FA levels measured in plasma phospholipids (PL. Methods The study sample consisted of 200 French-Canadians men and women aged between 18 to 55 years. Dietary data were collected using a validated FFQ. Fasting blood samples were collected and the plasma PL FA profile was measured by gas chromatography. Results Low intakes of n-3 long-chain FA together with low percentages of n-3 long-chain FA in plasma PL were found in French-Canadian population. Daily intakes of eicosapentaenoic acid (EPA, docosapentaenoic acid (DPA and docosahexaenoic acid (DHA were similar between men and women. Yet, alpha-linolenic acid (ALA and total n-3 FA intakes were significantly higher in men compared to women (ALA: 2.28 g and 1.69 g, p n-3 FA: 2.57 g and 1.99 g, p n-3 FA (men: r = 0.47, p  Conclusion Estimated n-3 long-chain FA intake among this young and well-educated French-Canadian population is lower than the recommendations. Further, FFQ data is comparable to plasma PL results to estimate DHA and total n-3 FA status in healthy individuals as well as to evaluate the EPA and DPA status in women. Overall, this FFQ could be used as a simple, low-cost tool in future studies to rank n-3 FA status of individuals.

  9. Reading Amount as a Mediator of the Effects of Intrinsic and Extrinsic Reading Motivation on Reading Comprehension

    Science.gov (United States)

    Schaffner, Ellen; Schiefele, Ulrich; Ulferts, Hannah

    2013-01-01

    This study examined the role of reading amount as a mediator of the effects of intrinsic and extrinsic reading motivation on higher order reading comprehension (comprised of paragraph-and passage-level comprehension) in a sample of 159 fifth-grade elementary students. A positive association between intrinsic reading motivation and reading amount…

  10. Reading motivation in elementary school students

    Directory of Open Access Journals (Sweden)

    Sonja Pečjak

    2005-02-01

    Full Text Available Reading motivation is one of the crucial factors of reading and consequently also learning efficiency of students. The purpose of the contribution is to establish the connection between dimensions of reading motivation and reading achievement in elementary school students. Participating in the study were 1073 third-grade and 1282 seventh-grade students. We used the questionnaire of reading motivation which consists of two factors: the reading competence factor and the interest and perceived reading importance factor. The findings of the study are the following: third-graders are more competent and more interested in reading compared to seventh-graders. The same is true for girls in both educational levels. Reading competence , interest and perceived reading importance reflect also in the actual reading behaviour of students – students who are more competent and more interested in reading read more frequently, for longer periods and more often autonomously decide to read compared to their less motivated peers. Higher reading motivation has implications also for higher reading efficiency. Namely, good readers are more competent, show higher interest and perceive reading as more important compared to average and bad readers.

  11. How Reading Volume Affects Both Reading Fluency and Reading Achievement

    Science.gov (United States)

    Allington, Richard L.

    2014-01-01

    Long overlooked, reading volume is actually central to the development of reading proficiencies, especially in the development of fluent reading proficiency. Generally no one in schools monitors the actual volume of reading that children engage in. We know that the commonly used commercial core reading programs provide only material that requires…

  12. Braille in the Sighted: Teaching Tactile Reading to Sighted Adults.

    Directory of Open Access Journals (Sweden)

    Łukasz Bola

    Full Text Available Blind people are known to have superior perceptual abilities in their remaining senses. Several studies suggest that these enhancements are dependent on the specific experience of blind individuals, who use those remaining senses more than sighted subjects. In line with this view, sighted subjects, when trained, are able to significantly progress in relatively simple tactile tasks. However, the case of complex tactile tasks is less obvious, as some studies suggest that visual deprivation itself could confer large advantages in learning them. It remains unclear to what extent those complex skills, such as braille reading, can be learnt by sighted subjects. Here we enrolled twenty-nine sighted adults, mostly braille teachers and educators, in a 9-month braille reading course. At the beginning of the course, all subjects were naive in tactile braille reading. After the course, almost all were able to read whole braille words at a mean speed of 6 words-per-minute. Subjects with low tactile acuity did not differ significantly in braille reading speed from the rest of the group, indicating that low tactile acuity is not a limiting factor for learning braille, at least at this early stage of learning. Our study shows that most sighted adults can learn whole-word braille reading, given the right method and a considerable amount of motivation. The adult sensorimotor system can thus adapt, to some level, to very complex tactile tasks without visual deprivation. The pace of learning in our group was comparable to congenitally and early blind children learning braille in primary school, which suggests that the blind's mastery of complex tactile tasks can, to a large extent, be explained by experience-dependent mechanisms.

  13. Braille in the Sighted: Teaching Tactile Reading to Sighted Adults.

    Science.gov (United States)

    Bola, Łukasz; Siuda-Krzywicka, Katarzyna; Paplińska, Małgorzata; Sumera, Ewa; Hańczur, Paweł; Szwed, Marcin

    2016-01-01

    Blind people are known to have superior perceptual abilities in their remaining senses. Several studies suggest that these enhancements are dependent on the specific experience of blind individuals, who use those remaining senses more than sighted subjects. In line with this view, sighted subjects, when trained, are able to significantly progress in relatively simple tactile tasks. However, the case of complex tactile tasks is less obvious, as some studies suggest that visual deprivation itself could confer large advantages in learning them. It remains unclear to what extent those complex skills, such as braille reading, can be learnt by sighted subjects. Here we enrolled twenty-nine sighted adults, mostly braille teachers and educators, in a 9-month braille reading course. At the beginning of the course, all subjects were naive in tactile braille reading. After the course, almost all were able to read whole braille words at a mean speed of 6 words-per-minute. Subjects with low tactile acuity did not differ significantly in braille reading speed from the rest of the group, indicating that low tactile acuity is not a limiting factor for learning braille, at least at this early stage of learning. Our study shows that most sighted adults can learn whole-word braille reading, given the right method and a considerable amount of motivation. The adult sensorimotor system can thus adapt, to some level, to very complex tactile tasks without visual deprivation. The pace of learning in our group was comparable to congenitally and early blind children learning braille in primary school, which suggests that the blind's mastery of complex tactile tasks can, to a large extent, be explained by experience-dependent mechanisms.

  14. The relative effects of reading interventions on reading and understanding from science text for high school students with learning disabilities

    Science.gov (United States)

    Seifert, Kathleen Louise

    High school teachers require their students to gain information independently from text; however, up to 40% of high school students are unable to do so. Therefore, it is necessary to examine the need for teaching reading at the secondary level. Twenty tenth-graders with learning disabilities participated in this study. The independent variable was the type of reading intervention: text reading, vocabulary learning, a combination or text reading and vocabulary learning, and no intervention. The dependent variables were reading fluency, vocabulary knowledge, and science knowledge. Student participants were assigned to conditions in a counter-balanced order using a within-subject design, and passages were coupled with intervention so that each passage appeared equally across interventions. Instructional reading passages were taken from a standard biology text, and treatment was conducted on these passages only. Two weeks following treatment, measures on generalization passages were taken. Data were analyzed using repeated measures ANOVA. Results from this study could have implications in furthering the body of research for teaching reading to adolescents.

  15. Sex based levels of C-reactive protein and white blood cell count in subjects with metabolic syndrome: Isfahan Healthy Heart Program

    Directory of Open Access Journals (Sweden)

    Mojgan Gharipour

    2013-01-01

    Full Text Available Background: C-reactive protein (CRP and white blood cell (WBC are proinflammatory markers. They are major pathophysiological for the development of metabolic syndrome (MetS. This study aimed to address the independent associations between MetS and WBC counts and serum CRP levels and evaluation of their magnitude in relation to the MetS, based on the sex in the Iranian adults. Materials and Methods: In this cross-sectional study, subjects who met the MetS criteria, based on the Adult Treatment Panel III were selected from the Isfahan Healthy Heart Program database. A questionnaire containing the demographic data, weight, height, waist, and hip circumference of the respondents was completed for each person. Blood pressure was measured and the anthropometric measurements were done, and fasting blood samples were taken for 2 h postload plasma glucose (2 hpp. Serum [total, high-density lipoprotein (HDL, and low-density lipoprotein] levels of cholesterol, triglyceride, and CRP as well as WBC counts were determined. The univariate analyses were carried out to assess the relation between the CRP levels, WBC counts with the MetS in both sexes the. Results: In men with the abdominal obesity, the higher levels of WBC count, high serum triglyceride and blood glucose levels, a low serum HDL level, and raised systolic and diastolic blood pressure were observed. However, the higher serum CRP levels were only observed in those with the low serum HDL-cholesterol levels. The mean values of the WBC counts were statistically different between the men with and without MetS, but the mean values of the CRP levels were similar between the two groups. In women, the mean values of WBC count and CRP levels were statistically different in the subjects with and without a MetS components (except for the low serum HDL levels and high diastolic blood pressure for the WBC measures and abdominal obesity for the CRP measures and for those with and without MetS. The age and

  16. A babel diagnóstica e a escolarização de sujeitos com autismo e psicose infantil: atos de uma leitura / Disgnosis babel and school inclusion of subjects with autism and child psychosis: acts of a reading

    Directory of Open Access Journals (Sweden)

    Carla K. Vasques

    2009-01-01

    and complex, the perspective adopted builds on Freud-lacanian psychoanalysis, philosophical-hermeneutics, special education and inclusive processes. Specifically, a reflection is posed on the place the diagnosis has in the construction of (impossibilitieswithin school based on the analysis of academic and scientific production on the issue for the past 28 years. The proposition is that diagnosis in central in the establishment of educationalpathways for such subjects. Diagnosis is often identified as an act of unveiling and/or decoding. From another perspective, it is defended that the relationship diagnosis-schoolingimplies the construction of a reading, the invention of possibilities. As it is not possible to determine the veracity of diverse theories, a schooling process includes constitutive unknowing. As there is no path pre-established guaranteed and anticipated by the diagnosis, teachers and school are responsible for their choices aiming their students school experience. Thus, the basis of their action is ethics, not a method or technique. As a metaphor of the interpretative work. I present the image of a library that is constructed, offers, inscribes and subscribes to the meeting between text and reader. Placing the library as a privileged space of such argumentation implies in taking language and reading as the center of discussions. It is a displacement of the focus of attention of the subject with autism or psychosis to the teacher, the other, who reads, interprets and builds schooling(inpossibilities.

  17. Reading Disorders:

    Science.gov (United States)

    Seaber, Emma

    2016-01-01

    This article explores the relationship between eating disorders and reading behaviors, arguing that there is a meaningful difference in a minority of readers' approach to and understanding of anorexia life-writing, and of literary texts more broadly. To illuminate this distinction, this article begins by considering the reported deleterious influence of Marya Hornbacher’s anorexia memoir, Wasted, elaborating the ways Hornbacher offers a positive presentation of anorexia nervosa that may, intentionally or not, induce certain readers to “try it” themselves. This is followed by an exploration of how Hornbacher’s own reading praxis is implicated in a discursive feedback loop around anorexia narratives. It concludes with a discussion of disordered reading attitudes in relation to the emergence of the “pro-anorexia” phenomenon. PMID:28569728

  18. Bidirectional Relations between Text Reading Prosody and Reading Comprehension in the Upper Primary School Grades: A Longitudinal Perspective.

    Science.gov (United States)

    Veenendaal, Nathalie J; Groen, Margriet A; Verhoeven, Ludo

    The purpose of this study was to examine the directionality of the relationship between text reading prosody and reading comprehension in the upper grades of primary school. We compared three theoretical possibilities: Two unidirectional relations from text reading prosody to reading comprehension and from reading comprehension to text reading prosody and a bidirectional relation between text reading prosody and reading comprehension. Further, we controlled for autoregressive effects and included decoding efficiency as a measure of general reading skill. Participants were 99 Dutch children, followed longitudinally, from fourth- to sixth-grade. Structural equation modeling showed that the bidirectional relation provided the best fitting model. In fifth-grade, text reading prosody was related to prior decoding and reading comprehension, whereas in sixth-grade, reading comprehension was related to prior text reading prosody. As such, the results suggest that the relation between text reading prosody and reading comprehension is reciprocal, but dependent on grade level.

  19. An investigation of Chinese university EFL learner’s foreign language reading anxiety, reading strategy use and reading comprehension performance

    Directory of Open Access Journals (Sweden)

    Zhongshe Lu

    2015-01-01

    Full Text Available The present study explored the interrelations between foreign language (FL reading anxiety, FL reading strategy use and their interactive effect on FL reading comprehension performance at the tertiary level in China. Analyses of the survey data collected from 1702 university students yielded the following results: (a Both Foreign Language Reading Anxiety Scale (FLRAS and Foreign Language Reading Strategy Use Scale (FLRSUS had important subcomponents, (b more than half of the students generally did not feel anxious when reading English, and were confident in and satisfied with their English reading proficiency. Meanwhile, (c more than half of them moderately used different types of reading strategies such as planning, checking and confirming, predicting and assessing, when reading English, (d compared with their female peers, male students felt significantly more anxious when facing reading activities, less satisfied with their English reading proficiency, and used specific analyzing and planning strategies significantly less often during a reading activity, (e FLRAS was significantly inversely related to FLRSUS, and both were significantly correlated with the students’ FL reading comprehension performance, and (f FLRAS (overall FL reading anxiety, FLRAS1 (general anxiety about FL reading, and FLRSUS2 (predicting strategies were good predictors of FL reading comprehension performance. Based on the findings, some implications are discussed.

  20. Dataset of mRNA levels for dopaminergic receptors, adrenoceptors and tyrosine hydroxylase in lymphocytes from subjects with clinically isolated syndromes

    Directory of Open Access Journals (Sweden)

    Marco Cosentino

    2016-12-01

    Full Text Available This data article presents a dataset of mRNA levels for dopaminergic receptors, adrenoceptors and for tyrosine hydoxylase, the rate-limiting enzyme in the synthesis of catecholamines, in peripheral blood mononuclear cells as well as in CD4+ T effector and regulatory cells from subjects with clinically isolated syndromes (CIS, which is a first episode of neurological disturbance(s suggestive of multiple sclerosis. CIS subjects are divided into two groups according to their eventual progression, after 12 months from CIS, to clinically established multiple sclerosis. The data reported are related to the article entitled "Dopaminergic receptors and adrenoceptors in circulating lymphocytes as putative biomarkers for the early onset and progression of multiple sclerosis" (M. Cosentino, M. Zaffaroni, M. Legnaro, R. Bombelli, L. Schembri, D. Baroncini, A. Bianchi, R. Clerici, M. Guidotti, P. Banfi, G. Bono, F. Marino, 2016 [1].