WorldWideScience

Sample records for subject matter included

  1. Changes in Dictionary Subject Matter

    DEFF Research Database (Denmark)

    Nielsen, Sandro

    2003-01-01

    The general content of the three editions of the Duden dictionary has undergone few changes. The most substantial changes are the addition of syllabification and the deletion of antonomy in respect of lemmata in the second and third editions. The concept of dictionary subject matter is questioned...

  2. Including subjectivity in the teaching of Psychopathology

    Directory of Open Access Journals (Sweden)

    Octavio Domont de Serpa Junior

    2007-01-01

    Full Text Available Current psychopathology studies have often been presented in their descriptive dimension. This perspective is important for teaching because it helps the students to recognize and identify the symptomatology of each psychopathology case. However, subjectivity, the experience of suffering and interpersonal aspects are all lost in this perspective. Coming from another psychopathology tradition - existential anthropology - this paper presents practical psychopathology teaching experience which considers such dimensions as being relevant to the understanding of mental suffering. The features and limitations of such traditions are briefly reviewed to support this teaching experience. Two new modalities of practical teaching, used in the discipline of "Special Psychopathology I" offered by the Department of Psychiatry and Forensic Medicine at the medical school of the Federal University of Rio de Janeiro for students of psychology, will be presented according to descriptive case study methodology. With these activities we also expect to change the practice of teaching. Traditionally, interviewing of in-patients by a large group of students who observe passively what is happening is the center of this kind of education. We intend to develop a model of teaching which is closer to the proposal of the Brazilian Psychiatric Reform which views mental illness as a complex phenomenon, always involving the relationship that the subject establishes with the world.

  3. Foodservice. Subject Matter Update 1986-87.

    Science.gov (United States)

    Oregon State Dept. of Education, Salem. Div. of Vocational Education.

    This publication recognizes the constantly changing requirements of the food service industry and varying conditions for employment opportunities. It addresses the goal of relevance in education by enabling the educator to make timely adjustments in the subject matter of the food service curriculum. There are six sections in this publication, each…

  4. 45 CFR 703.3 - Scope of subject matter.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which the...

  5. 49 CFR 1108.3 - Matters subject to arbitration.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Matters subject to arbitration. 1108.3 Section... BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE ARBITRATION OF CERTAIN DISPUTES SUBJECT TO THE STATUTORY JURISDICTION OF THE SURFACE TRANSPORTATION BOARD § 1108.3 Matters subject to arbitration. (a) Any...

  6. Conditioning audience patronage using subject matters in ...

    African Journals Online (AJOL)

    Films are subject-based and when producers set out to communicate their viewpoints, some do it flamboyantly while others take the subtle path. Unlike live theatre before it, the possibility of a virile spiral regarding the themes treated in movies can be as much repugnant as they can be fascinating. In this case, the audience ...

  7. Cortex Parcellation Associated Whole White Matter Parcellation in Individual Subjects

    Directory of Open Access Journals (Sweden)

    Patrick Schiffler

    2017-07-01

    Full Text Available The investigation of specific white matter areas is a growing field in neurological research and is typically achieved through the use of atlases. However, the definition of anatomically based regions remains challenging for the white matter and thus hinders region-specific analysis in individual subjects. In this article, we focus on creating a whole white matter parcellation method for individual subjects where these areas can be associated to cortex regions. This is done by combining cortex parcellation and fiber tracking data. By tracking fibers out of each cortex region and labeling the fibers according to their origin, we populate a candidate image. We then derive the white matter parcellation by classifying each white matter voxel according to the distribution of labels in the corresponding voxel from the candidate image. The parcellation of the white matter with the presented method is highly reliable and is not as dependent on registration as with white matter atlases. This method allows for the parcellation of the whole white matter into individual cortex region associated areas and, therefore, associates white matter alterations to cortex regions. In addition, we compare the results from the presented method to existing atlases. The areas generated by the presented method are not as sharply defined as the areas in most existing atlases; however, they are computed directly in the DWI space of the subject and, therefore, do not suffer from distortion caused by registration. The presented approach might be a promising tool for clinical and basic research to investigate modalities or system specific micro structural alterations of white matter areas in a quantitative manner.

  8. GP teachers' subject matter knowledge in the context of a tutorial: the preparation and delivery compared.

    Science.gov (United States)

    Cantillon, Peter; de Grave, Willem

    2012-05-01

    Clinical teachers use several different types of knowledge in the act of teaching. These include content knowledge (subject matter), knowledge of how to teach (pedagogy) and knowledge of learners (context). Most attention in faculty development has been on how to teach rather than what is taught. The quality of a teacher's subject matter knowledge is likely to be a critical determinant of how well a subject is presented, communicated and learned. We therefore set out to examine teachers' subject matter knowledge in the context of a general practice tutorial on grade 1 hypertension. This study is part of a larger study that employed a mixed method approach (concept mapping, phenomenological interviews and video-stimulated recall) to examine differences between clinical educators in subject matter knowledge, pedagogical knowledge and knowledge of the learning environment in the context of general practice education. This paper presents the concept map data findings from the larger study as well as the parts of the phenomenological interviews that relate to subject matter knowledge and beliefs. We found that there were marked differences in the quality and elaborative structure of GP teachers' knowledge in the concept maps completed prior to the tutorials. These differences were also predictive of differences in the content presented to learners in tutorials. Teachers' beliefs about subject matter were also likely to have affected what they chose to teach about and how they presented it. Subject matter knowledge varies considerably between GP teachers in the context of a common and relatively simple tutorial. Differences in the quality of subject matter knowledge matter because they have a profound effect on what is learned and how it is learned. Faculty development for clinical educators needs to pay heed to the quality of subject matter knowledge in addition to its more common pedagogical focus.

  9. Student Motivation in Science Subjects in Tanzania, Including Students' Voices

    Science.gov (United States)

    Mkimbili, Selina Thomas; Ødegaard, Marianne

    2017-12-01

    Fostering and maintaining students' interest in science is an important aspect of improving science learning. The focus of this paper is to listen to and reflect on students' voices regarding the sources of motivation for science subjects among students in community secondary schools with contextual challenges in Tanzania. We conducted a group-interview study of 46 Form 3 and Form 4 Tanzanian secondary school students. The study findings reveal that the major contextual challenges to student motivation for science in the studied schools are limited resources and students' insufficient competence in the language of instruction. Our results also reveal ways to enhance student motivation for science in schools with contextual challenges; these techniques include the use of questioning techniques and discourse, students' investigations and practical work using locally available materials, study tours, more integration of classroom science into students' daily lives and the use of real-life examples in science teaching. Also we noted that students' contemporary life, culture and familiar language can be utilised as a useful resource in facilitating meaningful learning in science in the school. Students suggested that, to make science interesting to a majority of students in a Tanzanian context, science education needs to be inclusive of students' experiences, culture and contemporary daily lives. Also, science teaching and learning in the classroom need to involve learners' voices.

  10. 22 CFR 61.6 - Consultation with subject matter specialists.

    Science.gov (United States)

    2010-04-01

    ... FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The... assisting the Department in its determination of whether materials for which export certification or import... determine eligibility of material for certification or authentication based in part on the opinions obtained...

  11. students' perception of teacher's knowledge of subject matter and ...

    African Journals Online (AJOL)

    ALEXANDER E. TIMOTHY

    The study used the ex post facto design to find out the influence of student's perception of teacher's knowledge of the subject matter on the Senior Secondary Three (SS 3) students' performance in reading comprehension. Questionnaires reading comprehension test were used in eliciting data. The data were subsequently ...

  12. Does tutor subject-matter expertise influence student achievement in ...

    African Journals Online (AJOL)

    Objective. To establish whether or not tutor subject-matter expertise influences student achievement in content-based examinations in the problem-based learning (PBL) curriculum at the University of Transkei (UNITRA) Medical School. Design. A retrospective study of MB ChB III student achievement in end-of-block ...

  13. Global anthropogenic emissions of particulate matter including black carbon

    Science.gov (United States)

    Klimont, Zbigniew; Kupiainen, Kaarle; Heyes, Chris; Purohit, Pallav; Cofala, Janusz; Rafaj, Peter; Borken-Kleefeld, Jens; Schöpp, Wolfgang

    2017-07-01

    This paper presents a comprehensive assessment of historical (1990-2010) global anthropogenic particulate matter (PM) emissions including the consistent and harmonized calculation of mass-based size distribution (PM1, PM2. 5, PM10), as well as primary carbonaceous aerosols including black carbon (BC) and organic carbon (OC). The estimates were developed with the integrated assessment model GAINS, where source- and region-specific technology characteristics are explicitly included. This assessment includes a number of previously unaccounted or often misallocated emission sources, i.e. kerosene lamps, gas flaring, diesel generators, refuse burning; some of them were reported in the past for selected regions or in the context of a particular pollutant or sector but not included as part of a total estimate. Spatially, emissions were calculated for 172 source regions (as well as international shipping), presented for 25 global regions, and allocated to 0.5° × 0.5° longitude-latitude grids. No independent estimates of emissions from forest fires and savannah burning are provided and neither windblown dust nor unpaved roads emissions are included. We estimate that global emissions of PM have not changed significantly between 1990 and 2010, showing a strong decoupling from the global increase in energy consumption and, consequently, CO2 emissions, but there are significantly different regional trends, with a particularly strong increase in East Asia and Africa and a strong decline in Europe, North America, and the Pacific region. This in turn resulted in important changes in the spatial pattern of PM burden, e.g. European, North American, and Pacific contributions to global emissions dropped from nearly 30 % in 1990 to well below 15 % in 2010, while Asia's contribution grew from just over 50 % to nearly two-thirds of the global total in 2010. For all PM species considered, Asian sources represented over 60 % of the global anthropogenic total, and residential combustion

  14. Global anthropogenic emissions of particulate matter including black carbon

    Directory of Open Access Journals (Sweden)

    Z. Klimont

    2017-07-01

    Full Text Available This paper presents a comprehensive assessment of historical (1990–2010 global anthropogenic particulate matter (PM emissions including the consistent and harmonized calculation of mass-based size distribution (PM1, PM2. 5, PM10, as well as primary carbonaceous aerosols including black carbon (BC and organic carbon (OC. The estimates were developed with the integrated assessment model GAINS, where source- and region-specific technology characteristics are explicitly included. This assessment includes a number of previously unaccounted or often misallocated emission sources, i.e. kerosene lamps, gas flaring, diesel generators, refuse burning; some of them were reported in the past for selected regions or in the context of a particular pollutant or sector but not included as part of a total estimate. Spatially, emissions were calculated for 172 source regions (as well as international shipping, presented for 25 global regions, and allocated to 0.5°  ×  0.5° longitude–latitude grids. No independent estimates of emissions from forest fires and savannah burning are provided and neither windblown dust nor unpaved roads emissions are included. We estimate that global emissions of PM have not changed significantly between 1990 and 2010, showing a strong decoupling from the global increase in energy consumption and, consequently, CO2 emissions, but there are significantly different regional trends, with a particularly strong increase in East Asia and Africa and a strong decline in Europe, North America, and the Pacific region. This in turn resulted in important changes in the spatial pattern of PM burden, e.g. European, North American, and Pacific contributions to global emissions dropped from nearly 30 % in 1990 to well below 15 % in 2010, while Asia's contribution grew from just over 50 % to nearly two-thirds of the global total in 2010. For all PM species considered, Asian sources represented over 60 % of the global

  15. Teachers mathematical communication profile in explaining subject matter

    Science.gov (United States)

    Umami, Rohmatul; Budayasa, I. Ketut; Suwarsono, St.

    2017-12-01

    This study aimed to see a teachers mathematical communication profile in explaining a subject matter. It is a qualitative research. A high-school junior teacher (i.e., a teacher with 1- to 5-year experience) teaching mathematics at X-Social Class was selected as the subject of this study. The data was collected by observing the teachers mathematical communication in explaining a given material (i.e., the rule of sine) in class and an in-depth interview would be organized respectively. The result showed that the junior teacher explained the subject matter in systematic, complete, fluent, and centered manner. In this case, she began with reminding students on the previous material related to the current material to be learned, informing the current learning objectives, and finally delivering the subject matter. To support her explanation, the teacher also provided some related information, led the students attention into the given material by asking them particular related questions, and did not use any confusing terms. However, the study found that some of high-school teachers still used less appropriate language in explaining materials.

  16. Including chemical-related impact categories in LCA on printed matter does it matter?

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Hansen, Morten Søes; Hauschild, Michael Zwicky

    2004-01-01

    global warming, acidification and nutrification. The studies focus on energy consumption including the emissions and impact categories related to energy. The chemical-related impact categories comprising ecotoxicity and human toxicity are not included at all or only to a limited degree. In this paper we...... environmental impacts and consumption of resources along the life cycle of a generic printed matter produced on a fictitious sheet feed offset printing industry in Europe. The results are to be used for developing ecolabelling criteria. Main activities at all stages in the life cycle are covered. However...

  17. Nuclear matter EoS including few-nucleon correlations

    Science.gov (United States)

    Röpke, G.

    2017-11-01

    Improving a mean-field approach to the nuclear matter equation of state (EoS), few-nucleon correlations are investigated. The contribution of clusters to the thermodynamic properties is suppressed at increasing density because of Pauli blocking. Continuum correlations are implemented. Applications to heavy-ion collisions (HIC) are discussed.

  18. One Health in food safety and security education: Subject matter outline for a curricular framework

    Directory of Open Access Journals (Sweden)

    John A. Angelos

    2017-06-01

    Full Text Available Educating students in the range of subjects encompassing food safety and security as approached from a One Health perspective requires consideration of a variety of different disciplines and the interrelationships among disciplines. The Western Institute for Food Safety and Security developed a subject matter outline to accompany a previously published One Health in food safety and security curricular framework. The subject matter covered in this outline encompasses a variety of topics and disciplines related to food safety and security including effects of food production on the environment. This subject matter outline should help guide curriculum development and education in One Health in food safety and security and provides useful information for educators, researchers, students, and public policy-makers facing the inherent challenges of maintaining and/or developing safe and secure food supplies without destroying Earth's natural resources.

  19. Trends in the journal of nematology, 1969-2009: authors, States, nematodes, and subject matter.

    Science.gov (United States)

    McSorley, R

    2011-06-01

    Issues of the Journal of Nematology from 1969-2009 were examined to determine trends in authorship and subject matter. Data were collected on authors, affiliations, locations, funding, nematodes, and nematological subject matter, and then compared among the 4 decades involved. Some of the more prominent changes noted included: a decrease (P Journal of Nematology in the 1990s and 2000s from a peak in the 1980s; an increase (P Journal of Nematology from 1969-2009. The greatest changes in subject matter were increases in papers on biological control and resistance in the 1990s and 2000s compared to the 1970s and 1980s. Additional trends and subjects are discussed, and data are provided comparing differences among the 4 decades for various aspects of nematology.

  20. One Health in food safety and security education: Subject matter outline for a curricular framework.

    Science.gov (United States)

    Angelos, John A; Arens, Amanda L; Johnson, Heather A; Cadriel, Jessica L; Osburn, Bennie I

    2017-06-01

    Educating students in the range of subjects encompassing food safety and security as approached from a One Health perspective requires consideration of a variety of different disciplines and the interrelationships among disciplines. The Western Institute for Food Safety and Security developed a subject matter outline to accompany a previously published One Health in food safety and security curricular framework. The subject matter covered in this outline encompasses a variety of topics and disciplines related to food safety and security including effects of food production on the environment. This subject matter outline should help guide curriculum development and education in One Health in food safety and security and provides useful information for educators, researchers, students, and public policy-makers facing the inherent challenges of maintaining and/or developing safe and secure food supplies without destroying Earth's natural resources.

  1. Trends in the Journal of Nematology, 1969-2009: Authors, States, Nematodes, and Subject Matter

    OpenAIRE

    McSorley, R.

    2011-01-01

    Issues of the Journal of Nematology from 1969-2009 were examined to determine trends in authorship and subject matter. Data were collected on authors, affiliations, locations, funding, nematodes, and nematological subject matter, and then compared among the 4 decades involved. Some of the more prominent changes noted included: a decrease (P < 0.05) in the number of papers published in the Journal of Nematology in the 1990s and 2000s from a peak in the 1980s; an increase (P < 0.05) in number o...

  2. Learning, knowledge building, and subject matter knowledge in school science

    Science.gov (United States)

    van Aalst, Jan Cornelis Wouterus

    Following a theoretical analysis of constructivist approaches to collaborative learning, a curriculum development model, the Learning to Knowledge Building Model, is proposed. Two empirical studies of student work with Computer Supported Intentional Learning Environment (CSILE) are then presented; these lend support to the model and explicate in detail the nature and extent of the knowledge developed by elementary school students. The first study is a content analysis of a database developed by a combined Grade 5/6 class as part of a unit on heat and matter, conducted after the children completed their work; the analysis assumes the point of view of a subject matter specialist in the field of the students' inquiry. The second study was conducted while the students' investigation was in progress, and takes the point of view of curriculum coverage; it involved a teacher who used a different model of database use, as well as different subject matter. The proposed LKB model is based on a distinction Bereiter and Scardamalia (1996a) have made between learning and knowledge building (i.e., progressive collaborative problem solving); its aim is to support the design and planning of curriculum units and classroom practices in which knowledge building is central. An important feature of the model is the attention given to ensuring that students learn to evaluate their knowledge and to ask the questions that can advance shared knowledge. Among the findings of the first study are: (a) students who wrote more notes that explicated their commonsense knowledge early in the unit, by means of mixed framework notes, tended to write more notes of high scientific merit later; (b) some of the students in this category tried out their ideas in diverse problem contexts; and (c) they tended to dominate the discussions they started. The second study provides additional insight into the role of the teacher, and the potential role of subject matter specialists, in knowledge building; it

  3. Single-subject grey matter graphs in Alzheimer's disease.

    Science.gov (United States)

    Tijms, Betty M; Möller, Christiane; Vrenken, Hugo; Wink, Alle Meije; de Haan, Willem; van der Flier, Wiesje M; Stam, Cornelis J; Scheltens, Philip; Barkhof, Frederik

    2013-01-01

    Coordinated patterns of cortical morphology have been described as structural graphs and previous research has demonstrated that properties of such graphs are altered in Alzheimer's disease (AD). However, it remains unknown how these alterations are related to cognitive deficits in individuals, as such graphs are restricted to group-level analysis. In the present study we investigated this question in single-subject grey matter networks. This new method extracts large-scale structural graphs where nodes represent small cortical regions that are connected by edges when they show statistical similarity. Using this method, unweighted and undirected networks were extracted from T1 weighted structural magnetic resonance imaging scans of 38 AD patients (19 female, average age 72±4 years) and 38 controls (19 females, average age 72±4 years). Group comparisons of standard graph properties were performed after correcting for grey matter volumetric measurements and were correlated to scores of general cognitive functioning. AD networks were characterised by a more random topology as indicated by a decreased small world coefficient (p = 3.53×10(-5)), decreased normalized clustering coefficient (p = 7.25×10(-6)) and decreased normalized path length (p = 1.91×10(-7)). Reduced normalized path length explained significantly (p = 0.004) more variance in measurements of general cognitive decline (32%) in comparison to volumetric measurements (9%). Altered path length of the parahippocampal gyrus, hippocampus, fusiform gyrus and precuneus showed the strongest relationship with cognitive decline. The present results suggest that single-subject grey matter graphs provide a concise quantification of cortical structure that has clinical value, which might be of particular importance for disease prognosis. These findings contribute to a better understanding of structural alterations and cognitive dysfunction in AD.

  4. Search for BSM physics including dark matter at ATLAS

    CERN Document Server

    Ju, Xiangyang; The ATLAS collaboration

    2016-01-01

    The increased centre-of-mass energy of the proton-proton collisions of the LHC run 2 gives a unique opportunity to extend the sensitivity to the production of particles not foreseen by the Standard Model. This talk summarises recent ATLAS results on BSM searches. Although the focus is on searches for production of DM particles, results include searches for heavy resonances in many final states and for production of supersymmetric particles.

  5. Landscape History and Theory: from Subject Matter to Analytical Tool

    Directory of Open Access Journals (Sweden)

    Jan Birksted

    2003-10-01

    Full Text Available This essay explores how landscape history can engage methodologically with the adjacent disciplines of art history and visual/cultural studies. Central to the methodological problem is the mapping of the beholder - spatially, temporally and phenomenologically. In this mapping process, landscape history is transformed from subject matter to analytical tool. As a result, landscape history no longer simply imports and applies ideas from other disciplines but develops its own methodologies to engage and influence them. Landscape history, like art history, thereby takes on a creative cultural presence. Through that process, landscape architecture and garden design regains the cultural power now carried by the arts and museum studies, and has an effect on the innovative capabilities of contemporary landscape design.

  6. What Do Subject Matter Experts Have to Say about Participating in Education and Outreach?

    Science.gov (United States)

    Manning, Colleen; NASA's Universe of Learning Team

    2018-01-01

    NASA’s Universe of Learning partners wish to actively engage with Subject Matter Experts (scientists and engineers) throughout the design, development, and delivery of products, programs, and professional development. In order to ensure these engagement efforts aligned with the needs of Subject Matter Experts, the external evaluators conducted an online survey. The subject pool included the scientists and engineers employed at the partner organizations as well as other scientists and engineers affiliated with NASA’s Astrophysics missions and research programs. This presentation will describe scientists’/engineers’ interest in various types of education/outreach, their availability to participate in education/outreach, factors that would encourage their participation in education/outreach, and the preparation and support they have for participation in education/outreach.

  7. 76 FR 34101 - In the Matter of Certain Integrated Circuits, Chipsets, and Products Containing Same Including...

    Science.gov (United States)

    2011-06-10

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION In the Matter of Certain Integrated Circuits, Chipsets, and Products Containing Same Including... integrated circuits, chipsets, and products containing same including televisions, media players, and cameras...

  8. On indexes and subject matter of “global competitiveness”

    Directory of Open Access Journals (Sweden)

    A. V. Korotkov

    2017-01-01

    Full Text Available The aim of the research is to analyze the subject matter of a country’s competitiveness and to characterize statistical indexes of competitiveness known in the international practice from the perspective of a more elaborated theory of market competition. This aim follows from the identified problems. First, there are no generally accepted interpretation and joint understanding of competition and competitiveness at country level. Even the international organizations giving estimations of global competitiveness disagree on definitions of competitiveness. Secondly, there is no relation to the theory of market competition in the available source materials on competitiveness of the country without original methodology. Thirdly, well-known statistical indexes of global competitiveness do not have enough theoretical justification and differ in sets of factors. All this highlights the incompleteness of the methodology and methodological support of studying competitiveness at country level.Materials and methods. The research is based on the methodology of statistics, economic theory and marketing. The authors followed the basic principle of statistical methodology – requirement of continuous combination of qualitative and quantitative analysis, when the research begins and ends with qualitative analysis. A most important section of statistical methodology is widely used – construction of statistical indexes. In the course of the analysis, a method of statistical classifications is applied. A significant role in the present research is given to the method of generalizing and analogue method, realizing that related terms should mean similar and almost similar contents. Modeling of competition and competitiveness is widely used in the present research, which made it possible to develop a logical model of competition following from the competition theory.Results. Based on the definitions’ survey the analysis of the subject matter of global

  9. The interrelationship between subject matter and school gardens

    DEFF Research Database (Denmark)

    Christensen, Jacob Højgaard; Wistoft, Karen

    2018-01-01

    This article maps out existing research regarding the effectiveness of integrated teaching in school gardens, i.e. including the math, languages and science subjects with their related objectives and curricula in school garden teaching and vice versa. The article is based on a literature review...... a standard garden curriculum is essential to planning, carrying out and evaluating effective school garden teaching in math, languages and science. Experiential learning and hands-on activities are teaching methods that immediately come to mind because they make the subject content less abstract, activate...... that concludes that school gardens have a predominantly positive influence on students’ learning outcome. However, there are a few school garden programmes that have the same or even a less beneficial influence on students’ learning outcome than traditional teaching. Thus, school gardens do not have...

  10. Cerebral white matter lesions and subjective cognitive dysfunction - The Rotterdam Scan Study

    NARCIS (Netherlands)

    de Groot, J.C.; de Leeuw, FE; Oudkerk, M; Hofman, A; Jolles, J; Breteler, MMB

    2001-01-01

    Objective: To determine the relationship between cerebral white matter lesions (WML) and subjective cognitive dysfunction. Background: Subjective cognitive dysfunction is present when a person perceives failures of cognitive function. When annoying enough, these failures will be expressed as

  11. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Filing of Patent... Text of Provisions and Clauses 52.227-10 Filing of Patent Applications—Classified Subject Matter. As prescribed at 27.203-2, insert the following clause: Filing of Patent Applications—Classified Subject Matter...

  12. Beyond "Either-Or" Thinking: John Dewey and Confucius on Subject Matter and the Learner

    Science.gov (United States)

    Tan, Charlene

    2016-01-01

    This article compares the educational thought of John Dewey and Confucius on the nature of and relationship between subject matter and the learner. There is a common perception in the existing literature and discourse that Dewey advocates child- or learner-centred education whereas Confucius privileges subject matter via textual transmission.…

  13. Florida Master Teacher Program: Testing Teacher Subject Matter Knowledge.

    Science.gov (United States)

    Lavely, Carolyn; And Others

    1986-01-01

    The efforts of the Florida Institute for Instructional Research and Practice in designing, developing, and analyzing the subject area knowledge tests of the Florida Master Teacher Program are described. A total of 13 subject area examinations was developed in 1984-85, and 5 additional tests were developed the following year. For each subject area…

  14. 76 FR 24051 - In the Matter of Certain Electronic Devices, Including Mobile Phones, Mobile Tablets, Portable...

    Science.gov (United States)

    2011-04-29

    ... COMMISSION In the Matter of Certain Electronic Devices, Including Mobile Phones, Mobile Tablets, Portable... within the United States after importation of certain electronic devices, including mobile phones, mobile... importation of certain electronic devices, including mobile phones, mobile tablets, portable music players...

  15. 75 FR 10502 - In the Matter of Certain Electronic Devices, Including Handheld Wireless Communications Devices...

    Science.gov (United States)

    2010-03-08

    ... COMMISSION In the Matter of Certain Electronic Devices, Including Handheld Wireless Communications Devices...-TA-667 and 337-TA-673, Certain Electronic Devices Including Handheld Wireless Communications Devices... electronic devices, including handheld wireless communications devices by reason of infringement of certain...

  16. 75 FR 36678 - In the Matter of Certain Authentication Systems, Including Software and Handheld Electronic...

    Science.gov (United States)

    2010-06-28

    ... COMMISSION In the Matter of Certain Authentication Systems, Including Software and Handheld Electronic..., and the sale within the United States after importation of certain authentication systems, including software and handheld electronic devices, by reason of infringement of certain claims of U.S. Patent No. 7...

  17. 75 FR 4583 - In the Matter of: Certain Electronic Devices, Including Mobile Phones, Portable Music Players...

    Science.gov (United States)

    2010-01-28

    ... COMMISSION In the Matter of: Certain Electronic Devices, Including Mobile Phones, Portable Music Players, and... electronic devices, including mobile phones, portable music players, and computers, by reason of infringement... mobile phones, portable music players, or computers that infringe one or more of claims 1-12 of U.S...

  18. 76 FR 45860 - In the Matter of Certain Electronic Devices, Including Wireless Communication Devices, Portable...

    Science.gov (United States)

    2011-08-01

    ... communication devices, portable music and data processing devices, and tablet computers by reason of... communication devices, portable music and data processing devices, and tablet computers that infringe one or... COMMISSION In the Matter of Certain Electronic Devices, Including Wireless Communication Devices, Portable...

  19. Generating a non-English subjectivity lexicon: relations that matter

    NARCIS (Netherlands)

    Jijkoun, V.; Hofmann, K.

    2009-01-01

    We describe a method for creating a non-English subjectivity lexicon based on an English lexicon, an online translation service and a general purpose thesaurus: Wordnet. We use a PageRank-like algorithm to bootstrap from the translation of the English lexicon and rank the words in the thesaurus by

  20. Preservice History Teachers' Perceptions of Subject Matter Competency

    Science.gov (United States)

    Yildirim, Tercan; Yazici, Fatih

    2017-01-01

    Teachers should be able to understand conceptual constructs, viewpoints, and principles related to their field and organize teaching process accordingly. This is valid also for history teachers. They are expected to comprehend the basic conceptions related to subject areas and reflect them on classroom practices. The association between subject…

  1. Didactic Matters in Teaching Subjects of Economics at the College

    Directory of Open Access Journals (Sweden)

    Rita Strazdienė

    2011-04-01

    Full Text Available It has been stated in Lithuania‘s National School Concept that the primary goal of the education of Lithuania is to secure the best possible comprehensive development of physical, psychological and spiritual human powers, to create conditions for the unfolding of the personal individuality. The subject of my teaching is economic theory. We face economic questions every day and in all areas of life. Therefore, my purpose is to acquaint college students, who do not study economics, with economic basics, to develop economic thinking and literacy. Greatest attention is paid to describe economic concepts and to use them in practice. Economics can not be learned through observing, one must work, analyse, solve practical exercises, search for correct answers. The purpose of the article is to assess the students‘ approach to the relevance of the subjects of economics. It is sought to identify the possibilities of applying new methods for teaching economic subjects and of selecting a teaching method in accordance with the students‘ level of preparation. The assessment of the research carried out enables to conclude that teaching economics forms students‘ capacities of a wide range, stimulates their self-expression, prepares young people to work in market conditions. The following methods of the research have been employed: pedagogic observation, questionnaire (survey, analysis of scientific literature and generalization.

  2. Subjectivity and Objectivity: A Matter of Life and Death?

    Directory of Open Access Journals (Sweden)

    Gertrudis Van de Vijver

    2008-10-01

    Full Text Available In this paper, it is argued that the question ldquo;What is life?rdquo; time and again emergesmdash;and within the confines of an objectivistic/subjectivistic frame of thought has to emergemdash;as a symptom, a non-deciphered, cryptic message that insists on being interpreted. br /Our hypothesis is that the failure to measure up the living to the standards of objectification has been taken too frequently from an objectivistic angle, leading to a simple postponement of an objective treatment of the living, and meanwhile confining it to the domain of the subjective, the relative and the metaphorical. As a consequence, the truly important question of the co-constitutive relation between objectivity and subjectivity is thereby evaded. A critical, transcendental account can be relevant in this regard, not only because of the fact that objectivity and subjectivity are seen as co-constitutive, but also because it addresses the question of the embeddedness of objectivity and subjectivity from within the living dynamics.br /This hypothesis will be articulated on the basis of Erwin Schrouml;dingerrsquo;s famous little book on ldquo;What is life?rdquo;, in dialogue with Robert Rosenrsquo;s critical reading of it. It appears that Schrouml;dinger considered the living as a genuine challenge for classical objectification procedures. However, it is doubtful whether this brought him to a critical reading of objectivity or to the acknowledgment of a constitutive role of subjectivity in relation to objectivity. We argue that his viewpoint has the merit ofnbsp; expressing the difficulty of the living within the field of the physical sciences, but does not really transcend the objectivism/subjectivism opposition. At this point, Rosenrsquo;s relational account takes up the challenge more radically by acknowledging the need for a new epistemology and a new metaphysics in relation to living systems, and by attributing a place to classical objectivity from within this

  3. 37 CFR 1.110 - Inventorship and date of invention of the subject matter of individual claims.

    Science.gov (United States)

    2010-07-01

    ... invention of the subject matter of individual claims. 1.110 Section 1.110 Patents, Trademarks, and... invention of the subject matter of individual claims. When more than one inventor is named in an application... claim in the application or patent. Where appropriate, the invention dates of the subject matter of each...

  4. OntoBrowser: a collaborative tool for curation of ontologies by subject matter experts.

    Science.gov (United States)

    Ravagli, Carlo; Pognan, Francois; Marc, Philippe

    2017-01-01

    The lack of controlled terminology and ontology usage leads to incomplete search results and poor interoperability between databases. One of the major underlying challenges of data integration is curating data to adhere to controlled terminologies and/or ontologies. Finding subject matter experts with the time and skills required to perform data curation is often problematic. In addition, existing tools are not designed for continuous data integration and collaborative curation. This results in time-consuming curation workflows that often become unsustainable. The primary objective of OntoBrowser is to provide an easy-to-use online collaborative solution for subject matter experts to map reported terms to preferred ontology (or code list) terms and facilitate ontology evolution. Additional features include web service access to data, visualization of ontologies in hierarchical/graph format and a peer review/approval workflow with alerting. The source code is freely available under the Apache v2.0 license. Source code and installation instructions are available at http://opensource.nibr.com This software is designed to run on a Java EE application server and store data in a relational database. philippe.marc@novartis.com. © The Author 2016. Published by Oxford University Press.

  5. Experiential Learning of Electronics Subject Matter in Middle School Robotics Courses

    Science.gov (United States)

    Rihtaršic, David; Avsec, Stanislav; Kocijancic, Slavko

    2016-01-01

    The purpose of this paper is to investigate whether the experiential learning of electronics subject matter is effective in the middle school open learning of robotics. Electronics is often ignored in robotics courses. Since robotics courses are typically comprised of computer-related subjects, and mechanical and electrical engineering, these…

  6. Fiberprint: A subject fingerprint based on sparse code pooling for white matter fiber analysis.

    Science.gov (United States)

    Kumar, Kuldeep; Desrosiers, Christian; Siddiqi, Kaleem; Colliot, Olivier; Toews, Matthew

    2017-09-01

    White matter characterization studies use the information provided by diffusion magnetic resonance imaging (dMRI) to draw cross-population inferences. However, the structure, function, and white matter geometry vary across individuals. Here, we propose a subject fingerprint, called Fiberprint, to quantify the individual uniqueness in white matter geometry using fiber trajectories. We learn a sparse coding representation for fiber trajectories by mapping them to a common space defined by a dictionary. A subject fingerprint is then generated by applying a pooling function for each bundle, thus providing a vector of bundle-wise features describing a particular subject's white matter geometry. These features encode unique properties of fiber trajectories, such as their density along prominent bundles. An analysis of data from 861 Human Connectome Project subjects reveals that a fingerprint based on approximately 3000 fiber trajectories can uniquely identify exemplars from the same individual. We also use fingerprints for twin/sibling identification, our observations consistent with the twin data studies of white matter integrity. Our results demonstrate that the proposed Fiberprint can effectively capture the variability in white matter fiber geometry across individuals, using a compact feature vector (dimension of 50), making this framework particularly attractive for handling large datasets. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Subjective matters: from image quality to image psychology

    Science.gov (United States)

    Fedorovskaya, Elena A.; De Ridder, Huib

    2013-03-01

    From the advent of digital imaging through several decades of studies, the human vision research community systematically focused on perceived image quality and digital artifacts due to resolution, compression, gamma, dynamic range, capture and reproduction noise, blur, etc., to help overcome existing technological challenges and shortcomings. Technological advances made digital images and digital multimedia nearly flawless in quality, and ubiquitous and pervasive in usage, provide us with the exciting but at the same time demanding possibility to turn to the domain of human experience including higher psychological functions, such as cognition, emotion, awareness, social interaction, consciousness and Self. In this paper we will outline the evolution of human centered multidisciplinary studies related to imaging and propose steps and potential foci of future research.

  8. Engaging Students with Subject Matter Experts and Science Content Through Classroom Connection Webinars

    Science.gov (United States)

    Graff, P. V.; Rampe, E.; Stefanov, W. L.; Vanderbloemen, L.; Higgins, M.

    2015-01-01

    Connecting students and teachers in classrooms with science, technology, engineering, and mathematics (STEM) experts provides an invaluable opportunity. Subject matter experts can share exciting science and science-related events as well as help to "translate" science being conducted by professionals. The Expedition Earth and Beyond (EEAB) Program, facilitated by the Astromaterials Research and Exploration Science (ARES) Division at the NASA Johnson Space Center, has been providing virtual access to subject matter experts through classroom connection webinars for the last five years. Each year, the reach of these events has grown considerably, especially over the last nine months. These virtual connections not only help engage students with role models, but are also designed to help teachers address concepts and content standards they are required to teach. These events also enable scientists and subject matter experts to help "translate" current science in an engaging and understandable manner while actively involving classrooms in the journey of science and exploration.

  9. Being in a romantic relationship is associated with reduced gray matter density in striatum and increased subjective happiness

    Directory of Open Access Journals (Sweden)

    Hiroaki Kawamichi

    2016-11-01

    Full Text Available Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that romantic relationship is associated with structural differences in the striatum related to the positive subjective experience of being in a romantic relationship. Because intimate romantic relationships contribute to perceived subjective happiness, this subjective enhancement of happiness might be accompanied by the experience of positive events related to being in a romantic relationship. To test this hypothesis and elucidate the structure involved, we compared subjective happiness, an indirect measure of the existence of positive experiences caused by being in a romantic relationship, of participants with or without romantic partners (N = 68. Furthermore, we also conducted a voxel-based morphometry (VBM study of the effects of being in a romantic relationship (N = 113. Being in a romantic relationship was associated with greater subjective happiness and reduced gray matter density within the right dorsal striatum. These results suggest that being in a romantic relationship enhances perceived subjective happiness via positive experiences. Furthermore, the observed reduction in gray matter density in the right dorsal striatum may reflect an increase in saliency of social reward within a romantic relationship. Thus, being in a romantic relationship is associated with positive experiences and a reduction of gray matter density in the right dorsal striatum, representing a modulation of social reward.

  10. Being in a Romantic Relationship Is Associated with Reduced Gray Matter Density in Striatum and Increased Subjective Happiness.

    Science.gov (United States)

    Kawamichi, Hiroaki; Sugawara, Sho K; Hamano, Yuki H; Makita, Kai; Matsunaga, Masahiro; Tanabe, Hiroki C; Ogino, Yuichi; Saito, Shigeru; Sadato, Norihiro

    2016-01-01

    Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that romantic relationship is associated with structural differences in the striatum related to the positive subjective experience of being in a romantic relationship. Because intimate romantic relationships contribute to perceived subjective happiness, this subjective enhancement of happiness might be accompanied by the experience of positive events related to being in a romantic relationship. To test this hypothesis and elucidate the structure involved, we compared subjective happiness, an indirect measure of the existence of positive experiences caused by being in a romantic relationship, of participants with or without romantic partners (N = 68). Furthermore, we also conducted a voxel-based morphometry study of the effects of being in a romantic relationship (N = 113). Being in a romantic relationship was associated with greater subjective happiness and reduced gray matter density within the right dorsal striatum. These results suggest that being in a romantic relationship enhances perceived subjective happiness via positive experiences. Furthermore, the observed reduction in gray matter density in the right dorsal striatum may reflect an increase in saliency of social reward within a romantic relationship. Thus, being in a romantic relationship is associated with positive experiences and a reduction of gray matter density in the right dorsal striatum, representing a modulation of social reward.

  11. The Effects of CLIL Education on the Subject Matter (Mathematics) and the Target Language (English)

    Science.gov (United States)

    Ouazizi, Khalid

    2016-01-01

    This paper investigates the effects of Content and Language Integrated Learning, CLIL for short, on both the attainment of the subject matter, mathematics in our case, hence the content aspect of CLIL. The second axes of research focuses on the effect of CLIL on the learners' proficiency vis-à-vis the language of instruction, epitomized here by…

  12. On the Importance of Subject Matter in Mathematics Education: A Conversation with Erich Christian Wittmann

    Science.gov (United States)

    Akinwunmi, Kathrin; Höveler, Karina; Schnell, Susanne

    2014-01-01

    Erich Christian Wittmann is one of the primary founders of mathematics education research as an autonomous field of work and research in Germany. The interview presented here reflects on his role in promoting mathematics education as a design science. The interview addresses the following topics: (1) The importance of subject matter in…

  13. The Structure of Subject Matter Content and Its Instructional Design Implications

    Science.gov (United States)

    Reigeluth, Charles M.; And Others

    1978-01-01

    Four types of fundamental structures are briefly described and illustrated: the learning hierarchy, the procedural hierarchy, the taxonomy, and the model. Then a theoretical framework is presented for classifying types of subject matter content, and some implications of these content classifications are discussed. (VT)

  14. Pre-Service Geography Teachers' Confidence in Geographical Subject Matter Knowledge and Teaching Geographical Skills

    Science.gov (United States)

    Harte, Wendy; Reitano, Paul

    2015-01-01

    This research tracked the confidence of 16 undergraduate and postgraduate pre-service geography teachers as they completed a single semester, senior phase geography curriculum course. The study focused specifically on the pre-service teachers' confidence in geographical subject matter knowledge and their confidence in teaching geographical skills.…

  15. The Designer-by-Assignment in Practice: Instructional Design Thinking of Subject Matter Experts

    Science.gov (United States)

    Pesce, Sandra V.

    2012-01-01

    Designers-by-assignment, or subject matter experts (SMEs) who are pressed into training service, have become common in the workplace. A review of more than 24 studies on expert and novice instructional designers, however, revealed that little is known about how designers-by-assignment think about design and make design decisions in the field. A…

  16. The Dialectical Nature of Writing and Its Implications for Learning Subject Matter Courses.

    Science.gov (United States)

    Males, Terry

    1997-01-01

    Looks at writing as a dialectical affair--"dialectic" refers both to the dialogical nature of writing and the opportunity it opens up for the writer in coming to a new understanding of the subject matter. Uses H. Gadamer's philosophical hermeneutics as a starting point for developing writing as a dialectical process. (PA)

  17. Reclaiming the Subject Matter as a Guide to Mutual Understanding: Effectiveness and Ethics in Interpersonal Interaction.

    Science.gov (United States)

    Deetz, Stanley

    1990-01-01

    Presents H. G. Gadamer's ontology of understanding as a developmental foundation for interpersonal system ethics. Conceptualizes interaction in terms of demand that the subject matter places on openly formed mutual understanding. Shows unethical interactions as practices which prohibit this development. Provides examples of processes by which…

  18. John Dewey on theory of learning and inquiry: The scientific method and subject matter

    Science.gov (United States)

    Chen, Po-Nien

    This study examines the educational debate between Dewey and some of his critics on the merits of learning the scientific method. Four of Dewey's critics---Hutchins, Hirsch, Hirst, and Scheffler criticize Dewey for over-emphasizing the importance of the scientific method and under-emphasizing the importance of subject matter in education. This dissertation argues that these critics misunderstand Dewey's use of the scientific method and its importance in education. It argues that Dewey conceives of the scientific method in two different ways: first as an attitude and second as a tool. It also argues that, by failing to understand this critical distinction, these critics misunderstand the role of the scientific method in education. The dissertation concludes by showing that, educationally, Dewey's ideas of the scientific method have different meanings in different context. It analyzes the scientific method as empirical method, critical thinking, cooperative learning, and creative thinking, and shows the place of subject matter in each of them.

  19. White Matter Hyperintensity Associations with Cerebral Blood Flow in Elderly Subjects Stratified by Cerebrovascular Risk.

    Science.gov (United States)

    Bahrani, Ahmed A; Powell, David K; Yu, Guoquiang; Johnson, Eleanor S; Jicha, Gregory A; Smith, Charles D

    2017-04-01

    This study aims to add clarity to the relationship between deep and periventricular brain white matter hyperintensities (WMHs), cerebral blood flow (CBF), and cerebrovascular risk in older persons. Deep white matter hyperintensity (dWMH) and periventricular white matter hyperintensity (pWMH) and regional gray matter (GM) and white matter (WM) blood flow from arterial spin labeling were quantified from magnetic resonance imaging scans of 26 cognitively normal elderly subjects stratified by cerebrovascular disease (CVD) risk. Fluid-attenuated inversion recovery images were acquired using a high-resolution 3-dimensional (3-D) sequence that reduced partial volume effects seen with slice-based techniques. dWMHs but not pWMHs were increased in patients at high risk of CVD; pWMHs but not dWMHs were associated with decreased regional cortical (GM) blood flow. We also found that blood flow in WM is decreased in regions of both pWMH and dWMH, with a greater degree of decrease in pWMH areas. WMHs are usefully divided into dWMH and pWMH regions because they demonstrate differential effects. 3-D regional WMH volume is a potentially valuable marker for CVD based on associations with cortical CBF and WM CBF. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  20. Problems Faced By Elementary School Second Grade English Subject Matter Teachers

    Directory of Open Access Journals (Sweden)

    Belgin Bal Incebacak

    2017-11-01

    Full Text Available The objective of thisstudy isto determine the problems experienced by subject matter teachers while instructing English lessons in the second grade of elementary school. What are the problemsfaced by English subject matter teachers when they instruct in 2nd grade lessons? In this research the descriptive modeling, which is one of the qualitative research methods, was employed. In accordance with this objective, we worked with 8 subject matter teachers from 5 different schoolsinAtakum and Ilkadim districtslocated in downtown Samsun, through easily accessible case sampling. The semi-structured “English Course Interview Form’’was applied to the teachers. In the study, descriptive survey model was employed, since it was aimed to reveal the current status of qualitative research methods.According to the results obtained from the research, the content was configured and presented under 5 themes. They were categorized as: 1. the problems experienced in classroom management, 2. the problems in physical and cognitive readiness, 3. the problems experienced in the learning and teacher process, 4. the problems seen in counseling, 5. the problems experienced in assessment and evaluation. In conclusion, the teachers stated that they had problems with managing the classroom, especially with the second grade students, whom are younger than others. It is observed that the change for teaching English at a younger age has been appropriate. Our teachersstated that they required in-service training so as to adapt to this aforementioned change.

  1. Subjective Response to Foot-Fall Noise, Including Localization of the Source Position

    DEFF Research Database (Denmark)

    Brunskog, Jonas; Hwang, Ha Dong; Jeong, Cheol-Ho

    2011-01-01

    Although an impact noise level is objectively evaluated the same according to current standards, a lightweight floor structure is often subjectively judged more annoying than a heavy homogeneous structure. The hypothesis of the present investigation is that the subjective judgment of impact noise...

  2. Rhetorical meta-language to promote the development of students' writing skills and subject matter understanding

    Science.gov (United States)

    Pelger, Susanne; Sigrell, Anders

    2016-01-01

    students' understanding of their subject matter.

  3. Girl Scouts and Subject Matter Experts: What’s the Connection?

    Science.gov (United States)

    Harman, Pamela; Girls Scouts of Northern California, Girl Scouts USA, Astronomical Society of the Pacifica, Univeristy of Arizona, and ARIES Scientific.

    2018-01-01

    Reaching for the Stars: NASA Science for Girl Scouts (Girl Scout Stars) fosters interaction between Girl Scouts and NASA Subject Matter Experts (SMEs), disseminates NASA STEM education-related resources, and engages Girl Scouts in NASA science and programs through space science badges and summer camps.A space science badge is in development for each of the six levels of Girl Scouts: Daisies, Grades K – 1; Brownies, Grades 2 -3; Juniors, Grades 4 -5; Cadettes, Grades 6 -8; Seniors, Grades 9 -10; and Ambassadors, Grades 11 -12. Indirectly, SMEs will reach tens of thousands of girls through the badges. SETI Institute SMEs Institute and SME Co-Is located at ARIES Scientific, Astronomical Society of the Pacific, University of Arizona, and Girl Scouts of Northern California developed and modified astronomy activities for the Girl Scouts USA badge writers to finesse into the Girl Scout formats. Revisions are reviewed by SMEs for accuracy. Each badge includes a step option that encourages girls to connect with SMEs, and recommendations for volunteers.A total of 127 girls from 31 states and the District of Columbia attendedTotal Eclipse Destination Camps at three locations. SMEs led activities and tours, inspiring girls to consider STEM careers. University of Arizona (U of A) SMEs lead Astronomy Camp for Volunteers, enabling volunteers to lead and inspire Girl Scouts in their respective Girl Scout Councils. A Destination Camp for Girl Scouts was also held at U of A. Girls experience authentic astronomy, learning how to collect and analyze data.Eleven teams comprised of two Girl Scouts, a volunteer or Council Staff, and an amateur astronomer attended Astronomy Club Camp, held at NASA GSFC. SMEs delivered science content. The girls will lead the formation of astronomy clubs in their councils, and will train their successors. SMEs will present and coach the clubs during monthly webinars.This presentation will highlight success and discuss lessons learned that are applicable

  4. Ab initio calculations on nuclear matter properties including the effects of three-nucleons interaction

    Science.gov (United States)

    Lovato, Alessandro

    2012-10-01

    In this thesis, the ground state properties of nuclear matter, namely the energy per particle and the response to weak probes, are computed, studying the effects of three nucleon interactions. Both the variational approach, based on the formalism of correlated basis function, and the auxiliary field diffusion Monte Carlo method have been used. A scheme suitable to construct a density-dependent two-nucleon potential in correlated basis approach is discussed. The density dependent potential resulting from UIX three-nucleon force has been employed in auxiliary field diffusion Monte Carlo calculations that turned out to be in very good agreement with correlated basis variational results. Hence, the underbinding of symmetric nuclear matter has to be ascribed to deficiencies of the UXI potential. A comparative analysis of the equations of state of both pure neutron matter and symmetric nuclear matter obtained using a new generation of "chiral inspired" local three-body potentials has been performed. These potentials provide an excellent description of the properties of light nuclei, as well as of the neutron-deuteron doublet scattering length. The weak response of symmetric nuclear matter has been computed at three-body cluster level. Two-body effective interactions and one-body effective operators have been derived within the formalism of correlated basis functions. The inclusion of the three-body cluster term in the effective interaction allowed for a direct inclusion of the UIX three-nucleon potential. Moreover, the sizable unphysical dependence of the effective weak operator is removed once the three-body cluster term is taken into account.

  5. 76 FR 58840 - In the Matter of Certain Display Devices, Including Digital Televisions and Monitors II; Notice...

    Science.gov (United States)

    2011-09-22

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION In the Matter of Certain Display Devices, Including Digital Televisions and Monitors II; Notice of... display devices, including digital televisions and monitors by reason of infringement of various claims of...

  6. 76 FR 13432 - In the Matter of Certain Display Devices, Including Digital Televisions and Monitors II; Notice...

    Science.gov (United States)

    2011-03-11

    ... COMMISSION In the Matter of Certain Display Devices, Including Digital Televisions and Monitors II; Notice of... United States after importation of certain display devices, including digital televisions and monitors by... digital televisions and monitors that infringe one or more of claims 41-44 of the `468 patent; claims 1-4...

  7. 76 FR 40930 - In the Matter of Certain Electronic Devices, Including Mobile Phones, Portable Music Players, and...

    Science.gov (United States)

    2011-07-12

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION In the Matter of Certain Electronic Devices, Including Mobile Phones, Portable Music Players, and... electronic devices, including mobile phones, portable music players, and computers by reason of infringement...

  8. Planetary Exploration Education: As Seen From the Point of View of Subject Matter Experts

    Science.gov (United States)

    Milazzo, M. P.; Anderson, R. B.; Gaither, T. A.; Vaughan, R. G.

    2016-12-01

    Planetary Learning that Advances the Nexus of Engineering, Technology, and Science (PLANETS) was selected as one of 27 new projects to support the NASA Science Mission Directorate's Science Education Cooperative Agreement Notice. Our goal is to develop and disseminate out-of-school time (OST) curricular and related educator professional development modules that integrate planetary science, technology, and engineering. We are a partnership between planetary science Subject Matter Experts (SMEs), curriculum developers, science and engineering teacher professional development experts and OST teacher networks. The PLANETS team includes the Center for Science Teaching and Learning (CSTL) at Northern Arizona University (NAU); the U.S. Geological Survey (USGS) Astrogeology Science Center (Astrogeology), and the Boston Museum of Science (MOS). Here, we present the work and approach by the SMEs at Astrogeology. As part of this overarching project, we will create a model for improved integration of SMEs, curriculum developers, professional development experts, and educators. For the 2016 and 2017 Fiscal Years, our focus is on creating science material for two OST modules designed for middle school students. We will begin development of a third module for elementary school students in the latter part of FY2017. The first module focuses on water conservation and treatment as applied on Earth, the International Space Station, and at a fictional Mars base. This unit involves the science and engineering of finding accessible water, evaluating it for quality, treating it for impurities (i.e., dissolved and suspended), initial use, a cycle of greywater treatment and re-use, and final treatment of blackwater. The second module involves the science and engineering of remote sensing as it is related to Earth and planetary exploration. This includes discussion and activities related to the electromagnetic spectrum, spectroscopy and various remote sensing systems and techniques. In

  9. The Examination of Secondary Education Chemistry Curricula Published between 1957-2007 in Terms of the Dimensions of Rationale, Goals, and Subject-Matter

    Science.gov (United States)

    Pekdag, Bulent; Erol, Hilal

    2013-01-01

    Fifteen secondary education chemistry curricula published from 1957 until 2007 were examined based on the dimensions of rationale, goals, and subject matter. An examination of documents in the scope of qualitative research was carried out in the study. The goals included in the examined chemistry curricula were analyzed according to the cognitive,…

  10. NPY mRNA Expression in the Prefrontal Cortex: Selective Reduction in the Superficial White Matter of Subjects with Schizoaffective Disorder

    Science.gov (United States)

    Morris, Harvey M.; Stopczynski, Rachelle E.; Lewis, David A.

    2009-01-01

    Background Alterations in the inhibitory circuitry of the dorsolateral prefrontal cortex (DLPFC) in schizophrenia include reduced expression of the messenger RNA (mRNA) for somatostatin (SST), a neuropeptide present in a subpopulation of γ-aminobutyric acid (GABA) neurons. Neuropeptide Y (NPY) is expressed in a subset of SST-containing interneurons and lower levels of NPY mRNA have also been reported in schizophrenia spectrum disorders. However, whether the alterations in these two transcripts identify the same, particularly vulnerable, subset of GABA neurons has not been examined. Methods We used in situ hybridization to quantify NPY mRNA levels in DLPFC gray and white matter from 23 pairs of subjects with schizophrenia or schizoaffective disorder and matched normal control subjects; results were compared to those from a previous study of SST mRNA expression in the same subjects. Results In contrast to SST mRNA, NPY mRNA levels were not significantly lower in the gray matter of subjects with schizophrenia or schizoaffective disorder. However, NPY, but not SST, mRNA expression was significantly lower in the superficial white matter of subjects with schizoaffective disorder. Conclusion These findings suggest that the alterations in SST-containing interneurons in schizophrenia and schizoaffective disorder are selective for the subset that do not express NPY mRNA, and that lower NPY mRNA expression in the superficial white matter may distinguish subjects with schizoaffective disorder from those with schizophrenia. PMID:19804960

  11. Habitual sleep durations and subjective sleep quality predict white matter differences in the human brain

    Directory of Open Access Journals (Sweden)

    Sakh Khalsa

    2017-06-01

    Full Text Available Self-imposed short sleep durations are increasingly commonplace in society, and have considerable health and performance implications for individuals. Reduced sleep duration over multiple nights has similar behavioural effects to those observed following acute total sleep deprivation, suggesting that lack of sleep affects brain function cumulatively. A link between habitual sleep patterns and functional connectivity has previously been observed, and the effect of sleep duration on the brain's intrinsic functional architecture may provide a link between sleep status and cognition. However, it is currently not known whether differences in habitual sleep patterns across individuals are related to changes in the brain's white matter, which underlies structural connectivity. In the present study we use diffusion–weighted imaging and a group comparison application of tract based spatial statistics (TBSS to investigate changes to fractional anisotropy (FA and mean diffusivity (MD in relation to sleep duration and quality, hypothesising that white matter metrics would be positively associated with sleep duration and quality. Diffusion weighted imaging data was acquired from a final cohort of 33 (23–29 years, 10 female, mean 25.4 years participants. Sleep patterns were assessed for a 14 day period using wrist actigraphs and sleep diaries, and subjective sleep quality with the Pittsburgh Sleep Quality Index (PSQI. Median splits based on total sleep time and PSQI were used to create groups of shorter/longer and poorer/better sleepers, whose imaging data was compared using TBSS followed by post-hoc correlation analysis in regions identified as significantly different between the groups. There were significant positive correlations between sleep duration and FA in the left orbito-frontal region and the right superior corona radiata, and significant negative correlations between sleep duration and MD in right orbito-frontal white matter and the right

  12. Verifying the attenuation of earplugs in situ: method validation on human subjects including individualized numerical simulations.

    Science.gov (United States)

    Bockstael, Annelies; Van Renterghem, Timothy; Botteldooren, Dick; D'Haenens, Wendy; Keppler, Hannah; Maes, Leen; Philips, Birgit; Swinnen, Freya; Vinck, Bart

    2009-03-01

    The microphone in real ear (MIRE) protocol allows the assessment of hearing protector's (HPD) attenuation in situ by measuring the difference between the sound pressure outside and inside the ear canal behind the HPD. Custom-made earplugs have been designed with an inner bore to insert the MIRE probe containing two microphones, the reference microphone measuring the sound pressure outside and the measurement microphone registering the sound pressure behind the HPD. Previous research on a head and torso simulator reveals a distinct difference, henceforth called transfer function, between the sound pressure at the MIRE measurement microphone and the sound pressure of interest at the eardrum. In the current study, similar measurements are carried out on humans with an extra microphone to measure the sound pressure at the eardrum. The resulting transfer functions confirm the global frequency dependency found earlier, but also show substantial variability between the ears with respect to the exact frequency and amplitude of the transfer functions' extrema. In addition, finite-difference time-domain numerical models of an ear canal with earplug are developed for each individual ear by including its specific geometrical parameters. This approach leads to a good resemblance between the simulations and their corresponding measurements.

  13. The Effects of Verbal Rewards and Punishment on Subject-Matter Growth of Culturally Disadvantaged First Grade Children.

    Science.gov (United States)

    Honeycutt, Joan K.; Soar, Robert S.

    The purpose of this study was to extend a relationship between teacher verbal rewarding and punishing behavior and subject matter growth previously obtained with middle-class postprimary children, with a different population; namely, first-grade, lower-class children. The subjects were 366 children and 20 teachers from first-grade classes…

  14. Knot numbers used as labels for identifying subject matter of a khipu

    Directory of Open Access Journals (Sweden)

    Alberto Saez-Rodriguez

    2013-03-01

    Full Text Available This investigation presents a new way to look at the numerical khipu, a knotted-string recording device from Pachacamac (Peru, and the types of information it contains. In addition to celestial coordinates, khipu knots apparently pertain to an early form of double-entry accounting. This study hypothesizes that the khipu sample has the recording capacity needed to register double-entry-like accounts. After the identification of its subject matter, the khipu sample was studied in an attempt to ascertain whether the knot values could represent instructions from the Inca state administration to a local accounting center. The results indicate that the numerical information in the pairing quadrants (determined by the distribution of S- and Z-knots should be read from top to bottom along the full length of the string and can then provide certain complementary details regarding the projected corn stocks of the Inca stat

  15. Subject matter knowledge, classroom management, and instructional practices in middle school science classrooms

    Science.gov (United States)

    Lee, Okhee

    This study examined the interrelationships among three major components of classroom teaching: subject matter content knowledge, classroom management, and instructional practices. The study involved two middle school science classes of different achievement levels taught by the same female teacher. The teacher held an undergraduate degree with a major in social studies and a minor in mathematics and science from an elementary teacher education program. The findings indicated that the teacher's limited knowledge of science content and her strict classroom order resulted in heavy dependence on the textbook and students' individual activities (e.g., seatwork) and avoidance of whole-class activities (e.g., discussion) similarly in both classes. Implications for educational practices and further research are discussed.

  16. 75 FR 448 - In the Matter of: Certain Authentication Systems, Including Software and Handheld Electronic...

    Science.gov (United States)

    2010-01-05

    ... Authentication Systems, Including Software and Handheld Electronic Devices; Notice of Investigation AGENCY: U.S... the sale within the United States after importation of certain authentication systems, including software and handheld electronic devices, by reason of infringement of certain claims of U.S. Patent No 7...

  17. The Role of Reading Comprehension in Large-Scale Subject-Matter Assessments

    Science.gov (United States)

    Zhang, Ting

    2013-01-01

    This study was designed with the overall goal of understanding how difficulties in reading comprehension are associated with early adolescents' performance in large-scale assessments in subject domains including science and civic-related social studies. The current study extended previous research by taking a cognition-centered approach based on…

  18. Grey-Matter Metabolism in Relation with White-Matter Lesions in Older Hypertensive Patients with Subjective Memory Complaints: A Pilot Voxel-Based Analysis Study.

    Science.gov (United States)

    Verger, Antoine; Hossu, Gabriela; Kearney-Schwartz, Anna; Bracard, Serge; Roch, Veronique; Van der Gucht, Axel; Fay, Renaud; Benetos, Athanase; Marie, Pierre-Yves; Joly, Laure

    2016-01-01

    This study aimed at assessing the changes in brain metabolism related to white-matter magnetic resonance (MR) hyperintensities of presumed vascular origin, with a voxel-based quantitative analysis of (18F)-fluorodesoxyglucose positron emission tomography (FDG-PET) imaging. Sixty older hypertensive patients with subjective memory complaints (75 ± 5 years, 34 women) were prospectively referred to FDG-PET and MRI brain imaging. The Statistical Parametric Mapping software was used to assess the correlation between brain distribution of FDG and white-matter hyperintensities assessed by the Fazekas score on MRI images. The Fazekas score was inversely related to FDG uptake, independently of age and gender, within 14 Brodmann areas located mainly in the frontal lobe but also in certain limbic, insular and temporal areas. This relationship was also found to be largely independent of the volume of grey matter expressed in percentage of cranial volume, an index of atrophy. White-matter MR hyperintensities of presumed vascular origin are cross-sectionally associated with a lower grey-matter metabolism, mainly but not only within frontal areas and independently of age, gender and grey-matter atrophy. © 2016 S. Karger AG, Basel.

  19. Subjective cognitive complaints included in diagnostic evaluation of dementia helps accurate diagnosis in a mixed memory clinic cohort

    DEFF Research Database (Denmark)

    Salem, L C; Vogel, Asmus Mejling; Ebstrup, J

    2015-01-01

    functions were assessed with the Mini-mental state examination (MMSE) and Addenbrooke's cognitive examination (ACE), and symptoms of depression were rated with Major Depression Inventory (MDI). All interviews and the diagnostic conclusion were blinded to the SMC score. RESULTS: We found that young patients......OBJECTIVE: Our objective was to examine the quantity and profile of subjective cognitive complaints in young patients as compared with elderly patients referred to a memory clinic. METHODS: Patients were consecutively recruited from the Copenhagen University Hospital Memory Clinic at Rigshospitalet....... In total, 307 patients and 149 age-matched healthy controls were included. Patients were classified in 4 diagnostic groups: dementia, mild cognitive impairment, affective disorders and no cognitive impairment. Subjective memory was assessed with subjective memory complaints (SMC) scale. Global cognitive...

  20. 'The body does matter': Women as embodied social subjects in Angela Carter's Nights at the Circus

    Directory of Open Access Journals (Sweden)

    Milosavljević Tatjana B.

    2017-01-01

    Full Text Available Postmodernism posed a crucial ontological challenge to reality, questioning what constitutes the real world, simultaneously interrogating the horizon of representation of this unstable reality in fiction. Feminism on the other hand equipped us with critical tools for interpreting the reality of being in the world in a gendered body, as well as with a conceptual apparatus for interpreting the manifold institutional and private oppressions of women's bodies that play out in women's daily lives and in the discourses that shape them, literary discourse being one of them. This paper argues that Angela Carter's 1984 novel Nights at the Circus, which is widely held as a postfeminist text due to its narrative commitment to transcending gender binaries, essentially uses the strategies of postmodern storytelling and characterization in order to explore women's embodied potentialities of agency i.e. their construction of subjectivity through body. We will argue that the hybrid magic realist narrative constructs Fevvers' body as a titillating postmodern performance, ontologically illusive and elusive, yet it grounds that same body in various socially effected predicaments and experiences that serve to show that even in the midst of a play of signifiers, in Patricia Waugh's words, 'the body does matter, at least to what has been the dominant perspective within British female fiction' (Waugh, 2006, p. 196. In other words, it may be argued that Carter's novel is invested in traditional second-wave feminist politics to the extent that it shows that a woman's body is an indispensable medium of being in the world with material consequences that bear on the formation of her subjectivity and possibility of agency, and through which she acts out her relationships to others and is acted upon.

  1. NASA's Universe of Learning: The Integral Role of Research Astronomers and Other Subject Matter Experts

    Science.gov (United States)

    Lee, Janice; Universe of Learning Team

    2018-01-01

    Astronomy seeks to understand the workings of the Universe on its largest scales, and to answer fundamental questions about the story of our origins. The science of astronomy thus naturally lends itself to informal education and public outreach activities, as it broadly captures the human imagination. There are at least three overall goals for investment of resources in Astronomy E/PO: to interest students in pursuing STEM education and careers; to develop Astronomy as context for teaching more basic physical and computer science in service of US National Education Goals; to help motivate continued public support of federally funded Astronomy research and technology development. Providing a full spectrum of opportunities for the public to learn about recent Astronomy discoveries is key to achieving these societal goals. Thus, the E/PO professional community must have an understanding of recent scientific/technological results, and engage with the researchers who are creating new knowledge to explicate that knowledge to the public. It stands to reason that researchers (or “subject matter experts, SMEs”) must be involved in and remain connected to the E/PO endeavor. In this talk, I will describe how research astronomers and other SMEs play an integral role in a full range of informal education programming developed by the NASA Universe of Learning collaboration, and opportunities to get involved.

  2. Cognitive Control and White Matter Callosal Microstructure in Methamphetamine Dependent Subjects: A DTI Study

    Science.gov (United States)

    Salo, Ruth; Nordahl, Thomas E; Buonocore, Michael H; Natsuaki, Yutaka; Waters, Christy; Moore, Charles D; Galloway, Gantt P; Leamon, Martin H

    2009-01-01

    Background Methamphetamine (MA) abuse causes damage to structures within the human cerebrum, with particular susceptibility to white matter (WM). Abnormalities have been reported in anterior regions with less evidence of changes in posterior regions. MA abusers have also shown deficits on attention tests that measure response conflict and cognitive control. Methods We examined cognitive control using a computerized measure of the Stroop selective attention task and indices of WM microstructure obtained from diffusion tensor imaging (DTI) in the callosal genu and splenium of 37 currently abstinent MA abusers and 17 non-substance abusing controls. Measurements of Fractional Anisotropy (FA), apparent diffusion coefficient (ADC) of callosal fibers and diffusion tensor eigenvalues were obtained in all subjects. Results The MA abusers exhibited greater Stroop reaction time interference (i.e., reduced cognitive control) [p=.04] compared to controls. After correcting for multiple comparisons, FA within the genu correlated significantly with measures of cognitive control in the MA abusers [p=.04, bonferroni corrected] but not in controls [p=.26]. Group differences in genu, but not splenium, FA were trend significant [p=.09]. Conclusions MA abuse appears to alter anterior callosal WM microstructure with less evidence of change within posterior callosal WM microstructure. DTI indices within the genu, but not splenium, correlated with measures of cognitive control in chronic MA abusers. PMID:18814867

  3. Subjectivity

    Directory of Open Access Journals (Sweden)

    Jesús Vega Encabo

    2015-11-01

    Full Text Available In this paper, I claim that subjectivity is a way of being that is constituted through a set of practices in which the self is subject to the dangers of fictionalizing and plotting her life and self-image. I examine some ways of becoming subject through narratives and through theatrical performance before others. Through these practices, a real and active subjectivity is revealed, capable of self-knowledge and self-transformation. 

  4. What Subject Matter Knowledge Do Second-Level Teachers Need to Know to Teach Trigonometry? An Exploration and Case Study

    Science.gov (United States)

    Walsh, Richard; Fitzmaurice, Olivia; O'Donoghue, John

    2017-01-01

    This study reports on the level of trigonometry Subject Matter Knowledge (SMK) of third and final-year pre-service second-level mathematics teachers () at an Irish third-level institution. The aim of the study was to determine if this sample of prospective teachers has an appropriate level of SMK to teach second-level trigonometric concepts. The…

  5. A Methodology for Investigating the Interactions of Individual Differences and Subject Matter Characteristics with Instructional Methods. ; Report 67.

    Science.gov (United States)

    Reigeluth, Charles M.

    This paper presents a general model for conceptualizing and testing the interactions of individual differences and subject-matter characteristics with instructional methods. The model postulates certain ways of classifying the variables of interest in such investigations and of conceptualizing the cause-and-effect relationships among those classes…

  6. Which One Is Better? Jigsaw II versus Jigsaw IV on the Subject of the Building Blocks of Matter and Atom

    Science.gov (United States)

    Turkmen, Hakan; Buyukaltay, Didem

    2015-01-01

    In this study, the effect of using Jigsaw II and Jigsaw IV techniques on the subject of "Atoms-The Basic Unit of Matter" in science course of 6th grade on academic achievement was examined. Pre-test post-test control group research was used in the study. Study population is all secondary schools in Turgutlu district of Manisa province…

  7. "Frustrated" or "Surprised?" An Examination of the Perspectives of Spanish Teacher Candidates regarding the Praxis II Subject-Matter Tests

    Science.gov (United States)

    Moser, Kelly

    2012-01-01

    Researchers (Sandarg & Schomber, 2009; Wilkerson, Schomber, & Sandarg, 2004) have urged the profession to develop a new subject-matter licensure test to reflect the best practices in the foreign language classroom. In October 2010, the Praxis II: World Language Test joined the Praxis Series. Given that this standards-driven test differs…

  8. Reflective Pedagogy: The Integration of Methodology and Subject-Matter Content in a Graduate-Level Course

    Science.gov (United States)

    Jakeman, Rick C.; Henderson, Markesha M.; Howard, Lionel C.

    2017-01-01

    This article presents a critical reflection on how we, instructors of a graduate-level course in higher education administration, sought to integrate theoretical and subject-matter content and research methodology. Our reflection, guided by autoethnography and teacher reflection, challenged both our assumptions about curriculum design and our…

  9. The Knowledge Base of Subject Matter Experts in Teaching: A Case Study of a Professional Scientist as a Beginning Teacher

    Science.gov (United States)

    Diezmann, Carmel M.; Watters, James J.

    2015-01-01

    One method of addressing the shortage of science and mathematics teachers is to train scientists and other science-related professionals to become teachers. Advocates argue that as discipline experts these career changers can relate the subject matter knowledge to various contexts and applications in teaching. In this paper, through interviews and…

  10. Shared Knowledge among Graphic Designers, Instructional Designers and Subject Matter Experts in Designing Multimedia-Based Instructional Media

    Science.gov (United States)

    Razak, Rafiza Abdul

    2013-01-01

    The research identified and explored the shared knowledge among the instructional multimedia design and development experts comprising of subject matter expert, graphic designer and instructional designer. The knowledge shared by the team was categorized into three groups of multimedia design principles encompasses of basic principles, authoring…

  11. The Impact of Self-Perceived Subject Matter Knowledge on Pedagogical Decisions in EFL Grammar Teaching Practices

    Science.gov (United States)

    Sanchez, Hugo Santiago

    2014-01-01

    Recent developments in language teacher cognition research highlight the need to explore subject matter knowledge in relation to classroom practice. This study examines the impact of two foreign language teachers' knowledge about grammar upon their pedagogical decisions. The primary database consisted of classroom observations and post-lesson…

  12. The Effect of Applying Elements of Instructional Design on Teaching Material for the Subject of Classification of Matter

    Science.gov (United States)

    Ozdilek, Zehra; Ozkan, Muhlis

    2009-01-01

    The aim of this study was to examine the effect of instructional materials for the subject of classification of matter as solids, liquids and gases that were developed using a holistic instructional design model on student achievement. In the study a pre-test/post-test with control group experimental design was used. The study was conducted in the…

  13. Resting state cortical electroencephalographic rhythms are related to gray matter volume in subjects with mild cognitive impairment and Alzheimer's disease.

    Science.gov (United States)

    Babiloni, Claudio; Carducci, Filippo; Lizio, Roberta; Vecchio, Fabrizio; Baglieri, Annalisa; Bernardini, Silvia; Cavedo, Enrica; Bozzao, Alessandro; Buttinelli, Carla; Esposito, Fabrizio; Giubilei, Franco; Guizzaro, Antonio; Marino, Silvia; Montella, Patrizia; Quattrocchi, Carlo C; Redolfi, Alberto; Soricelli, Andrea; Tedeschi, Gioacchino; Ferri, Raffaele; Rossi-Fedele, Giancarlo; Ursini, Francesca; Scrascia, Federica; Vernieri, Fabrizio; Pedersen, Torleif Jan; Hardemark, Hans-Goran; Rossini, Paolo M; Frisoni, Giovanni B

    2013-06-01

    Cortical gray matter volume and resting state cortical electroencephalographic rhythms are typically abnormal in subjects with amnesic mild cognitive impairment (MCI) and Alzheimer's disease (AD). Here we tested the hypothesis that in amnesic MCI and AD subjects, abnormalities of EEG rhythms are a functional reflection of cortical atrophy across the disease. Eyes-closed resting state EEG data were recorded in 57 healthy elderly (Nold), 102 amnesic MCI, and 108 AD patients. Cortical gray matter volume was indexed by magnetic resonance imaging recorded in the MCI and AD subjects according to Alzheimer's disease neuroimaging initiative project (http://www.adni-info.org/). EEG rhythms of interest were delta (2-4 Hz), theta (4-8 Hz), alpha1 (8-10.5 Hz), alpha2 (10.5-13 Hz), beta1 (13-20 Hz), beta2 (20-30 Hz), and gamma (30-40 Hz). These rhythms were indexed by LORETA. Compared with the Nold, the MCI showed a decrease in amplitude of alpha 1 sources. With respect to the Nold and MCI, the AD showed an amplitude increase of delta sources, along with a strong amplitude reduction of alpha 1 sources. In the MCI and AD subjects as a whole group, the lower the cortical gray matter volume, the higher the delta sources, the lower the alpha 1 sources. The better the score to cognitive tests the higher the gray matter volume, the lower the pathological delta sources, and the higher the alpha sources. These results suggest that in amnesic MCI and AD subjects, abnormalities of resting state cortical EEG rhythms are not epiphenomena but are strictly related to neurodegeneration (atrophy of cortical gray matter) and cognition. Copyright © 2011 Wiley Periodicals, Inc.

  14. Method for contamination control and barrier apparatus with filter for containing waste materials that include dangerous particulate matter

    Science.gov (United States)

    Pinson, Paul A.

    1998-01-01

    A container for hazardous waste materials that includes air or other gas carrying dangerous particulate matter has incorporated in barrier material, preferably in the form of a flexible sheet, one or more filters for the dangerous particulate matter sealably attached to such barrier material. The filter is preferably a HEPA type filter and is preferably chemically bonded to the barrier materials. The filter or filters are preferably flexibly bonded to the barrier material marginally and peripherally of the filter or marginally and peripherally of air or other gas outlet openings in the barrier material, which may be a plastic bag. The filter may be provided with a backing panel of barrier material having an opening or openings for the passage of air or other gas into the filter or filters. Such backing panel is bonded marginally and peripherally thereof to the barrier material or to both it and the filter or filters. A coupling or couplings for deflating and inflating the container may be incorporated. Confining a hazardous waste material in such a container, rapidly deflating the container and disposing of the container, constitutes one aspect of the method of the invention. The chemical bonding procedure for producing the container constitutes another aspect of the method of the invention.

  15. Methods to model particulate matter clarification of unit operations subject to unsteady loadings.

    Science.gov (United States)

    Spelman, David; Sansalone, John J

    2017-05-15

    Stormwater, and also wastewater unit operations (UOs) to a much lower extent, are subject to unsteady hydrodynamic and particulate matter (PM) fluxes. Simulating fully transient clarification of hetero-disperse PM requires much greater computational expense compared to steady simulations. An alternative to fully unsteady methods are stepwise steady (SS) methods which use stepwise steady flow transport and fate to approximate unsteady PM clarification of a UO during transient hydraulic loadings such as rainfall-runoff. The rationale is reduced computational effort for computational fluid dynamics (CFD) compared to simulating continuous unsteadiness of such events. An implicit solution stepwise steady (IS3) method is one approach which builds upon previous SS methods. The IS3 method computes steady flows that are representative of unsteady PM transport throughout an unsteady loading. This method departs from some previous SS methods that assume PM fate can be simulated with an instantaneous clarifier (basin) influent flowrate coupled with a PM input. In this study, various SS methods were tested for basins of varying size and residence time to examine PM fate. Differences between SS methods were a function of turnover fraction indicating the role of unsteady flowrates on PM transport for larger basins of longer residence times. The breakpoint turnover fraction was between two and three. The IS3 method best approximated unsteady behavior of larger basins. These methods identified limitations when utilizing standard event-based loading analysis for larger basins. For basins with a turnover fraction less than two, the majority of effluent PM did not originate from the event-based flow; originating from previous event loadings or existing storage. Inter- and multiple event processes and interactions, that are dependent on this inflow turnover fraction, are not accounted for by single event-based inflow models. Results suggest the use of long-term continuous modeling

  16. DNA as patentable subject matter and a narrow framework for addressing the perceived problems caused by gene patents.

    Science.gov (United States)

    Schilling, Stephen H

    2011-12-01

    Concerns about the alleged harmful effects of gene patents--including hindered research and innovation and impeded patient access to high-quality genetic diagnostic tests--have resulted in overreactions from the public and throughout the legal profession. These overreactions are exemplified by Association for Molecular Pathology v. U.S. Patent and Trademark Office, a 2010 case in the Southern District of New York that held that isolated DNA is unpatentable subject matter under 35 U.S.C. § 101. The problem with these responses is that they fail to adequately consider the role that gene patents and patents on similar biomolecules play in facilitating investment in the costly and risky developmental processes required to transform the underlying inventions into marketable products. Accordingly, a more precisely refined solution is advisable. This Note proposes a narrowly tailored set of solutions to address the concerns about gene patents without destroying the incentives for companies to create and commercialize inventions derived from these and similar patents.

  17. Developing Pedagogical Content Knowledge for Teaching a New Topic: More Than Teaching Experience and Subject Matter Knowledge

    Science.gov (United States)

    Chan, Kennedy Kam Ho; Yung, Benny Hin Wai

    2017-03-01

    Teaching experience has been identified as an important factor in pedagogical content knowledge (PCK) development. However, little is known about how experienced teachers may draw on their previous experience to facilitate their PCK development. This study examined how two experienced high school biology teachers approached the teaching of a newly introduced topic in the curriculum, polymerase chain reaction and their PCK development from the pre-lesson planning phase through the interactive phase to the post-lesson reflection phase. Multiple data sources included classroom observations, field notes, semi-structured interviews and classroom artefacts. It was found that the teachers' previous experience informed their planning for teaching the new topic, but in qualitatively different ways. This, in turn, had a bearing on their new PCK development. Subject matter knowledge (SMK) can not only facilitate but may also hinder this development. Our findings identify two types of experienced teachers: those who can capitalise on their previous teaching experiences and SMK to develop new PCK and those who do not. The critical difference is whether in the lesson planning stage, the teacher shows the disposition to draw on a generalised mental framework that enables the teacher to capitalise on his existing SMK to develop new PCK. Helping teachers to acquire this disposition should be a focus for teacher training in light of continuous curriculum changes.

  18. Integrating Multicultural Subject Matters into Teaching Strategies of Elementary School Teachers (The U.S. State of Kansas

    Directory of Open Access Journals (Sweden)

    Stanka Lunder Verlič

    2014-12-01

    Full Text Available The following academic article is based on a PhD thesis that is currently being completed, titled Education and Qualifications of Elementary School Teachers in the U.S. State of Kansas and Slovenia for teaching in classes with immigrant children. The research study titled Integrating Multicultural Subject Matters into Teaching Strategies of Elementary School Teachers (The U.S. State of Kansas, conducted in 2007 based on a sample of 89 elementary school teachers in the U.S. State of Kansas, represents one aspect of assessing the adequacy of undergraduate education regarding multicultural subject matters for elementary school teachers in Slovenia and the U.S. (State of Kansas as well as the qualifications of elementary school teachers of both countries for working with immigrant children. Despite the long-standing tradition of multicultural education in western countries, the research results for Kansas elementary school teachers showed a presence of significant discrepancies between the actual and optimal integration of multicultural subject matters. These results indicate that future undergraduate study programs will have to invest more time in developing multicultural skills and providing practical experiences for working in a diverse environment.

  19. Subject Matter Expert Evaluation of Multi-Flight Common Route Advisories

    Science.gov (United States)

    Bilimoria, Karl D.; Hayashi, Miwa; Sheth, Kapil

    2017-01-01

    manager finds the advisory to be operationally appropriate, he or she would coordinate with the Area Supervisor(s) of the sectors that currently control the flights in the advisory. When the traffic manager accepts the MFCR advisory via the user interface, the corresponding flight plan amendments would be sent to the displays of the appropriate sector controllers, using the Airborne Re-Routing (ABRR) capability which is scheduled for nationwide operation in 2017. The sector controllers would then offer this time-saving route modification to the pilots of the affected flights via datalink (or voice), and implement the corresponding flight plan amendment if the pilots accept it. MFCR is implemented as an application in the software environment of the Future Air traffic management Concepts Evaluation Tool (FACET). This paper focuses on an initial subject matter expert (SME) evaluation of MFCR. The evaluation covers MFCRs operational concept, algorithm, and user interface.

  20. Variations in some environmental characteristics including C and N stable isotopic composition of suspended organic matter in the Mandovi estuary

    Digital Repository Service at National Institute of Oceanography (India)

    Maya, M.V.; Soares, M.A.; Agnihotri, R.; Pratihary, A.K.; Karapurkar, S.; Naik, H.; Naqvi, S.W.A.

    ) of suspended organic matter produced/transported during the monsoon and post-monsoon seasons of year 2007 provides a baseline dataset for future isotopic studies in such type of tropical estuaries...

  1. CosmoQuest: Supporting Subject Matter Experts in Broadening the Impacts of their Work beyond their Institutional Walls.

    Science.gov (United States)

    Noel-Storr, J.; Buxner, S.; Grier, J.; Gay, P.

    2016-12-01

    CosmoQuest is a virtual research facility, which, like its physical counterparts, provides tools for scientists to acquire reduced data products (thanks to our cadre of citizen scientists working to analyze images and produce results online), and also to participate in education and outreach activities either directly through CosmoQuest activities (such as CosmoAcademy and the Educators' Zone) or with the support of CosmoQuest. Here, we present our strategies to inspire, engage and support Subject Matter Experts (SMEs - Scientists, Engineers, Technologists and Mathematicians) in activities outside of their institutions, and beyond college classroom teaching. We provide support for SMEs who are interested in increasing the impacts of their science knowledge and expertise by interacting with people online, or in other venues outside of their normal work environment. This includes a broad spectrum of opportunities for those interested in hosting webinars; running short courses for the public; using Facebook, Twitter or other social media to communicate science; or other diverse activities such as supporting an open house, science fair, or star party. As noted by Katheryn Woods-Townsend and colleagues, "...face-to-face interactions with scientists allowed students to view scientists as approachable and normal people, and to begin to understand the range of scientific areas and careers that exist. Scientists viewed the scientist-student interactions as a vehicle for science communication" (2015). As CosmoQuest fosters these relationships, it We present a framework for SMEs which combine opportunities for continuing professional development (virtually and in person at conferences) with ongoing online support, creating a dynamic professional learning network. The goal of this is to deepen SME capacity-knowledge, attitudes and behaviors-both encouraging and empowering them to connect to broader audiences in new ways.

  2. Bromatological composition and dry matter digestibility of millet cultivars subjected to nitrogen doses

    Directory of Open Access Journals (Sweden)

    W.H.D. Buso

    2014-06-01

    Full Text Available The bromatological composition and in vitro dry matter digestibility of millet cultivars were assessed for different nitrogen doses and two sowing seasons in the Ceres municipality of Goiás state, Brazil. The treatments consisted of three millet cultivars (ADR-7010, ADR-500 and BRS-1501, four nitrogen (N doses (0, 50, 100 and 200kg ha-1 of N and two sowing seasons. Three replicates and a randomised block design with a 3 x 4 x 2 factorial scheme were used. Two cuttings were performed in each season when plants reached an average height of 0.70 cm. No significant interactions were observed between or among cultivars for N doses and dry matter (DM, crude protein (CP, neutral detergent fibre (NDF and acid detergent fibre (ADF contents. The DM, CP, NDF and ADF contents were significantly different between N doses. The DM and CP contents increased as the N dose increased to 100kg ha-1. The maximum DM and CP contents were 11.14 and 22.53%, respectively. The NDF and ADF contents were higher in the control treatment (60.11 and 30.01%, respectively. In addition, the lowest ADF and NDF concentrations occurred at an N dose of 50kg ha-1 (56.33 and 30.23%, respectively. The DM contents were higher for the February sowing, with an average of 10.59%. The highest CP and ADF contents were found for the December sowing (22.46 and 31.58%, respectively. No significant differences were found for millet cultivars, N doses or sowing seasons. A significant interaction was found between sowing season and millet cultivar. The BRS-1501 cultivar had a higher in vitro dry matter digestibility in the December/2010 sowing (73.88%.

  3. Individualized Gaussian process-based prediction and detection of local and global gray matter abnormalities in elderly subjects.

    Science.gov (United States)

    Ziegler, G; Ridgway, G R; Dahnke, R; Gaser, C

    2014-08-15

    Structural imaging based on MRI is an integral component of the clinical assessment of patients with potential dementia. We here propose an individualized Gaussian process-based inference scheme for clinical decision support in healthy and pathological aging elderly subjects using MRI. The approach aims at quantitative and transparent support for clinicians who aim to detect structural abnormalities in patients at risk of Alzheimer's disease or other types of dementia. Firstly, we introduce a generative model incorporating our knowledge about normative decline of local and global gray matter volume across the brain in elderly. By supposing smooth structural trajectories the models account for the general course of age-related structural decline as well as late-life accelerated loss. Considering healthy subjects' demography and global brain parameters as informative about normal brain aging variability affords individualized predictions in single cases. Using Gaussian process models as a normative reference, we predict new subjects' brain scans and quantify the local gray matter abnormalities in terms of Normative Probability Maps (NPM) and global z-scores. By integrating the observed expectation error and the predictive uncertainty, the local maps and global scores exploit the advantages of Bayesian inference for clinical decisions and provide a valuable extension of diagnostic information about pathological aging. We validate the approach in simulated data and real MRI data. We train the GP framework using 1238 healthy subjects with ages 18-94 years, and predict in 415 independent test subjects diagnosed as healthy controls, Mild Cognitive Impairment and Alzheimer's disease. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  4. Constraints from Ly-α forests on non-thermal dark matter including resonantly-produced sterile neutrinos

    Science.gov (United States)

    Baur, Julien; Palanque-Delabrouille, Nathalie; Yèche, Christophe; Boyarsky, Alexey; Ruchayskiy, Oleg; Armengaud, Éric; Lesgourgues, Julien

    2017-12-01

    We use the large BOSS DR9 sample of quasar spectra to constrain two cases of non-thermal dark matter models: cold-plus-warm dark matter (C+WDM) where the warm component is a thermal relic, and sterile neutrinos resonantly produced in the presence of a lepton asymmetry (RPSN). We establish constraints on the thermal relic mass mx and its relative abundance Fwdm=Ωwdm/Ωdm using a suite of cosmological hydrodynamical simulations in 28 C+WDM configurations. We find that the 3σ bounds in the mx - Fwdm parameter space approximately follow Fwdm ~ 0.35 (keV/mx)-1.37 from BOSS data alone. We also establish constraints on sterile neutrino mass and mixing angle by further producing the non-linear flux power spectrum of 8 RPSN models, where the input linear power spectrum is computed directly from the particles distribution functions. We find values of lepton asymmetries for which sterile neutrinos as light as ~ 6.5 keV (resp. 3.5 keV) are consistent with BOSS data at the 2σ (resp. 3σ) level. These limits tighten by close to a factor of 2 for values of lepton asymmetries departing from those yielding the coolest distribution functions. Our Lyman-α forest bounds can be additionally strengthened if we include higher-resolution data from XQ-100, HIRES and MIKE that allow us to probe smaller scales. At these scales, the measured flux power spectrum exhibits a suppression that can be due to Doppler broadening, IGM pressure smoothing or free-streaming of WDM particles. In order to distinguish between these mechanisms, thermal history at redshifts z >= 5 should be determined. In the current work, we show that if one extrapolates temperatures from lower redshifts via broken power laws in T0 and γ, then our 3σ C+WDM {bounds strengthen to Fwdm ~ 0.20 (keV/mx)-1.37, and the lightest resonantly-produced sterile neutrinos consistent with our extended data set have masses of ~ 7.0 keV at the 3σ level. In particular, using dedicated hydrodynamical simulations, we show that} a

  5. A common NTRK2 variant is associated with emotional arousal and brain white-matter integrity in healthy young subjects

    Science.gov (United States)

    Spalek, K; Coynel, D; Freytag, V; Hartmann, F; Heck, A; Milnik, A; de Quervain, D; Papassotiropoulos, A

    2016-01-01

    Dysregulation of emotional arousal is observed in many psychiatric diseases such as schizophrenia, mood and anxiety disorders. The neurotrophic tyrosine kinase receptor type 2 gene (NTRK2) has been associated with these disorders. Here we investigated the relation between genetic variability of NTRK2 and emotional arousal in healthy young subjects in two independent samples (n1=1171; n2=707). In addition, diffusion tensor imaging (DTI) data in a subgroup of 342 participants were used to identify NTRK2-related white-matter structure differences. After correction for multiple testing, we identified a NTRK2 single nucleotide polymorphism associated with emotional arousal in both samples (n1: Pnominal=0.0003, Pcorrected=0.048; n2: Pnominal=0.0141, Pcorrected=0.036). DTI revealed significant, whole-brain corrected correlations between emotional arousal and brain white-matter mean diffusivity (MD), as well as significant, whole-brain corrected NTRK2 genotype-related differences in MD (PFWE<0.05). Our study demonstrates that genetic variability of NTRK2, a susceptibility gene for psychiatric disorders, is related to emotional arousal and—independently—to brain white-matter properties in healthy individuals. PMID:26978740

  6. A common NTRK2 variant is associated with emotional arousal and brain white-matter integrity in healthy young subjects.

    Science.gov (United States)

    Spalek, K; Coynel, D; Freytag, V; Hartmann, F; Heck, A; Milnik, A; de Quervain, D; Papassotiropoulos, A

    2016-03-15

    Dysregulation of emotional arousal is observed in many psychiatric diseases such as schizophrenia, mood and anxiety disorders. The neurotrophic tyrosine kinase receptor type 2 gene (NTRK2) has been associated with these disorders. Here we investigated the relation between genetic variability of NTRK2 and emotional arousal in healthy young subjects in two independent samples (n1=1171; n2=707). In addition, diffusion tensor imaging (DTI) data in a subgroup of 342 participants were used to identify NTRK2-related white-matter structure differences. After correction for multiple testing, we identified a NTRK2 single nucleotide polymorphism associated with emotional arousal in both samples (n1: Pnominal=0.0003, Pcorrected=0.048; n2: Pnominal=0.0141, Pcorrected=0.036). DTI revealed significant, whole-brain corrected correlations between emotional arousal and brain white-matter mean diffusivity (MD), as well as significant, whole-brain corrected NTRK2 genotype-related differences in MD (PFWEemotional arousal and-independently-to brain white-matter properties in healthy individuals.

  7. Relationship between mathematics teacher subject matter knowledge, pedagogical content knowledge and professional development needs

    Science.gov (United States)

    Tajudin, Nor'ain Mohd; Chinnappan, Mohan; Saad, Noor Shah

    2017-05-01

    Two key variables emerged from the literature review is that Specific Matter Knowledge [SMK] and Pedagogical Content Knowledge [PCK] can influence the mathematics teachers' Professional Development [PD] needs. However, the key variables of SMK and PCK that were being investigated were not defined clearly. Empirical evidence that support relationship between SMK and PD and PCK and PD were not verified. In addition, how does PCK mediate SMK and PD is not clear and somewhat lacking. Therefore, the purpose of this paper was to examine the relationship between primary mathematics teacher's SMK, PCK and PD needs. Results of path analysis with SmartPLS indicated that the direct effect of SMK on PD was mediated via PCK. This data provide support for the claim that PD programs for future teachers of primary mathematics should be driven by a more nuanced understanding of the link between SMK and PCK.

  8. Subjective Evaluations of Alcohol-Related Consequences among College Students: Experience with Consequences Matters

    Science.gov (United States)

    Leavens, Eleanor L.; Leffingwell, Thad R.; Miller, Mary Beth; Brett, Emma I.; Lombardi, Nathaniel

    2017-01-01

    Objective: Research suggests college students rate some alcohol-related consequences less negatively than others, yet it is unclear how or when these differences in perception develop. The current study compared college students' subjective evaluations of alcohol-related consequences that they had and had not experienced in order to test the…

  9. Being in a romantic relationship is associated with reduced gray matter density in striatum and increased subjective happiness

    OpenAIRE

    Hiroaki Kawamichi; Sugawara, Sho K.; Hamano, Yuki H.; Kai Makita; Masahiro Matsunaga; Tanabe, Hiroki C.; Yuichi Ogino; Shigeru Saito; Norihiro Sadato

    2016-01-01

    Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that ro...

  10. Being in a Romantic Relationship Is Associated with Reduced Gray Matter Density in Striatum and Increased Subjective Happiness

    OpenAIRE

    Kawamichi, Hiroaki; Sugawara, Sho K.; Hamano, Yuki H.; Makita, Kai; Matsunaga, Masahiro; Tanabe, Hiroki C.; Ogino, Yuichi; Saito, Shigeru; Sadato, Norihiro

    2016-01-01

    Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that ro...

  11. Relative activity of cerebral subcortical gray matter in varying states of attention and awareness in normal subjects and patient studies

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, M.; Chen, C.T.; Levy, J.; Wagner, N.; Spire, J.P.; Jacobsen, J.; Meltzer, H.; Metz, J.; Beck, R.N.

    1985-05-01

    An important aspect of the study of brain function involves measurement of the relationships; between activities in the subcortical gray matter of the caudate and of the thalamus; and between these structures and functional cortical areas. The authors have studied these relationships in 22 subjects under different conditions of activation, sleep and sensory deprivation using a PET VI system and F-18-2DG to determine regional cerebral metabolism. Subject activating conditions were maintained throughout the period of equilibration of F-18-2DG and E.E.G.'s were monitored. Multiple tomographic slices of 1-2 million counts were obtained simultaneously with slice separation of 14mm and each plane parallel to the cantho-meatal line. In activated and non-activated awake conditions for normal subjects, left and right thalmus-to-caudate ratios were similar and greater than unity. This relationship was maintained in non-REM sleep, but was reversed and divergent in REM sleep and sensory deprivation; this was also evident in 3/4 narcoleptics awake and asleep in non-REM and REM and 2/3 schizophrenics and affective disorder, subjects. This approach appears to have potential for characterizating normal and disordered regional cerebral function.

  12. Concentration dynamics and biodegradability of dissolved organic matter in wetland soils subjected to experimental warming.

    Science.gov (United States)

    Wang, Hang; Holden, Joseph; Zhang, Zhijian; Li, Meng; Li, Xia

    2014-02-01

    Dissolved organic matter (DOM) is the most bioavailable soil organic pool. Understanding how DOM responds to elevated temperature is important for forecasting soil carbon (C) dynamics under climate warming. Here a 4.5-year field microcosm experiment was carried out to examine temporal DOM concentration dynamics in soil pore-water from six different subtropical wetlands. Results are compared between control (ambient temperature) and warmed (+5°C) treatments. UV-visible and fluorescence spectroscopy was performed to reveal DOM structural complexity at the end of the warming incubation. Elevated temperature resulted in initially (1 to 2.5 years) high pore-water DOM concentrations in warmed samples. These effects gradually diminished over longer time periods. Of the spectral indices, specific UV absorbance at 280 nm and humification index were significantly higher, while the signal intensity ratio of the fulvic-like to humic-like fluorescence peak was lower in warmed samples, compared to the control. Fluorescence regional integration analysis further suggested that warming enhanced the contribution of humic-like substances to DOM composition for all tested wetlands. These spectral fingerprints implied a declined fraction of readily available substrates in DOM allocated to microbial utilization in response to 4.5 years of warming. As a negative feedback, decreased DOM biodegradability may have the potential to counteract initial DOM increases and alleviate C loss in water-saturated wetland soils. © 2013.

  13. Comorbid subjective health complaints in patients with sciatica: a prospective study including comparison with the general population.

    Science.gov (United States)

    Grøvle, Lars; Haugen, Anne J; Ihlebaek, Camilla M; Keller, Anne; Natvig, Bård; Brox, Jens I; Grotle, Margreth

    2011-06-01

    Chronic nonspecific low back pain is accompanied by high rates of comorbid mental and physical conditions. The aims of this study were to investigate if patients with specific back pain, that is, sciatica caused by lumbar herniation, report higher rates of subjective health complaints (SHCs) than the general population and if there is an association between change in sciatica symptoms and change in SHCs over a 12-month period. A multicenter cohort study of 466 sciatica patients was conducted with follow-up at 3 months and 1 year. Comorbid SHCs were measured by 27 items of the SHC inventory. Odds ratios (ORs) for each SHC were calculated with comparison to a general population sample (n=928) by logistic regression. The SHC number was calculated by summing all complaints present. At baseline, the ORs for reporting SHCs for the sciatica patients were significantly elevated in 15 of the 27 items with a mean (S.D.) SHC number of 7.5 (4.4), compared to 5.2 (4.4) in the general population (Psciatica, the SHC number was reduced to normal levels. Among those with persisting or worsening sciatica, the number increased to a level almost double that of the general population. Compared to the general population, the prevalence of subjective health complaints in sciatica is increased. During follow-up, the number of health complaints increased in patients with persisting or worsening sciatica. Copyright © 2010 Elsevier Inc. All rights reserved.

  14. How to foster student-student learning of science? The student, the teacher and the subject matter

    Science.gov (United States)

    Bianchini, Julie A.

    2011-12-01

    In this response to Konstantinos Alexakos, Jayson K. Jones, and Victor H. Rodriguez's study, I discuss ways attending to student membership in groups can both inform research on equity and diversity in science education and improve the teaching of science to all students. My comments are organized into three sections: how underrepresented students' experiences in science classrooms are shaped by their peers; how science teachers can help students listen to and learn from one another; and how the subject matter can invite or discourage student participation in science. More specifically, I underscore the need for teachers and students to listen to one another to promote student learning of science. I also highlight the importance of science education researchers and science teachers viewing students both as individuals and as members of multiple groups; women of color, for example, should be understood as similar to and different from each other, from European American women and from ethnic minorities in general.

  15. Using Folk Dance and Geography to Teach Interdisciplinary, Multicultural Subject Matter: A School-Based Study

    Science.gov (United States)

    Rovegno, Inez; Gregg, Madeleine

    2007-01-01

    Background: Many scholars have called for physical education to be part of interdisciplinary units at the elementary level. The study of Native American cultures is required in most North American elementary schools. Folk dance, however, has traditionally included Western European folk dances, square dance, and, more recently, line dancing. In our…

  16. Insight on AV-45 binding in white and grey matter from histogram analysis: a study on early Alzheimer's disease patients and healthy subjects

    Energy Technology Data Exchange (ETDEWEB)

    Nemmi, Federico; Saint-Aubert, Laure; Peran, Patrice [Inserm, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse (France); Universite de Toulouse, UPS, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse, Toulouse (France); Adel, Djilali; Salabert, Anne-Sophie; Payoux, Pierre [Inserm, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse (France); Universite de Toulouse, UPS, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse, Toulouse (France); Centre Hospitalier Universitaire de Toulouse, Service de Medecine Nucleaire, Pole Imagerie, Toulouse (France); Pariente, Jeremie [Inserm, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse (France); Universite de Toulouse, UPS, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse, Toulouse (France); Centre Hospitalier Universitaire de Toulouse, Service de Neurologie, Pole Neurosciences, Toulouse (France); Barbeau, Emmanuel J. [Centre Hospitalier Universitaire de Toulouse, Service de Neurologie, Pole Neurosciences, Toulouse (France); Universite de Toulouse, UPS, Centre de Recherche Cerveau et Cognition, CNRS, CerCo, Toulouse (France)

    2014-07-15

    AV-45 amyloid biomarker is known to show uptake in white matter in patients with Alzheimer's disease (AD), but also in the healthy population. This binding, thought to be of a non-specific lipophilic nature, has not yet been investigated. The aim of this study was to determine the differential pattern of AV-45 binding in white matter in healthy and pathological populations. We recruited 24 patients presenting with AD at an early stage and 17 matched, healthy subjects. We used an optimized positron emission tomography-magnetic resonance imaging (PET-MRI) registration method and an approach based on an intensity histogram using several indices. We compared the results of the intensity histogram analyses with a more canonical approach based on target-to-cerebellum Standard Uptake Value (SUVr) in white and grey matter using MANOVA and discriminant analyses. A cluster analysis on white and grey matter histograms was also performed. White matter histogram analysis revealed significant differences between AD and healthy subjects, which were not revealed by SUVr analysis. However, white matter histograms were not decisive to discriminate groups, and indices based on grey matter only showed better discriminative power than SUVr. The cluster analysis divided our sample into two clusters, showing different uptakes in grey, but also in white matter. These results demonstrate that AV-45 binding in white matter conveys subtle information not detectable using the SUVr approach. Although it is not more efficient than standard SUVr in discriminating AD patients from healthy subjects, this information could reveal white matter modifications. (orig.)

  17. Elevated leukocyte count in asymptomatic subjects is associated with a higher risk for cerebral white matter lesions.

    Science.gov (United States)

    Kim, Chi Kyung; Lee, Seung-Hoon; Kim, Beom Joon; Ryu, Wi-Sun; Choi, Seung Ho; Oh, Byung-Hee; Yoon, Byung-Woo

    2011-04-01

    Cerebral white matter lesions (WMLs) are radiologic markers of small vessel disease in brain, and inflammatory processes were related to WMLs. We propose to determine if elevated leukocyte count was associated with a higher risk of WMLs. 1586 asymptomatic subjects who visited our hospital for a routine health check-up were enrolled. Leukocyte counts were measured and the presence of moderate to severe WMLs was determined by brain MRI. Thirty (1.9%) had moderate to severe WMLs, and a significant greater proportion (4.1%) of subjects in the highest leukocyte count quartile had moderate to severe WMLs. After adjusting by C-reactive protein, aspirin use and cardiovascular risk factors, the highest quartile of leukocyte count (≥6.7×10⁹/L) was significantly associated with moderate to severe WMLs compared with the lowest quartile [adjusted odds ratio, 4.03; 95% confidence interval, 1.05-15.5]. The authors report for the first time that an elevated leukocyte count is independently associated with moderate to severe WMLs. Copyright © 2010. Published by Elsevier B.V.

  18. Importance to include the term superficial musculoaponeurotic system in medical subject headings and in the international anatomical nomenclature.

    Science.gov (United States)

    Ferreira, Lydia Massako; Locali, Rafael Fagionato; Lapin, Guilherme Abbud Franco; Hochman, Bernardo

    2011-06-01

    To investigate the relevance of the term superficial musculoaponeurotic system (SMAS) and demonstrate that this term is important enough to be added to the MeSH database and listed in International Anatomical Nomenclature. Terms related to SMAS were selected from original articles retrieved from the ISI Web of Science and MEDLINE (PubMed) databases. Groups of terms were created to define a search strategy with high-sensitivity and restricted to scientific periodicals devoted to plastic surgery. This study included articles between January 1996 and May 2009, whose titles, abstracts, and keywords were searched for SMAS-related terms and all occurrences were recorded. A total of 126 original articles were retrieved from the main periodicals related to plastic surgery in the referred databases. Of these articles, 51.6% had SMAS-related terms in the abstract only, and 25.4% had SMAS-related terms in both the title and abstract. The term 'superficial musculoaponeurotic system' was present as a keyword in 19.8% of the articles. The most frequent terms were 'SMAS' (71.4%) and superficial musculoaponeurotic system (62.7%). The term SMAS refers to a structure relevant enough to start a discussion about indexing it as a keyword and as an official term in Terminologia Anatomica: International Anatomical Terminology.

  19. The Subject's Matter

    DEFF Research Database (Denmark)

    in the significance of the body in our mental life. The sixteen specially commissioned essays in this book reflect the advances in these fields. The book is divided into three parts, each part covering a topic central to an explanation of bodily self-awareness: representation of the body; the sense of bodily......The body may be the object we know the best. It is the only object from which we constantly receive a flow of information through sight and touch; and it is the only object we can experience from the inside, through our proprioceptive, vestibular, and visceral senses. Yet there have been very few...... books that have attempted to consolidate our understanding of the body as it figures in our experience and self-awareness. This volume offers an interdisciplinary and comprehensive treatment of bodily self-awareness, the first book to do so since the landmark 1995 collection The Body and the Self...

  20. Is welfare all that matters? A discussion of what should be included in policy-making regarding animals

    DEFF Research Database (Denmark)

    Yeates, J.W.; Röcklinsberg, H.; Gjerris, Mickey

    2011-01-01

    Policy-making concerned with animals often includes human interests, such as economy, trade, environmental protection, disease control, species conservation etc. When it comes to the interests of the animals, such policy-making often makes use of the results of animal welfare science to provide...... to animals. This can be considered as a problem of what is included in welfare science, or of what is included in policy. This suggests two possible solutions: expanding animal welfare science to address all ethical concerns about animals’ interests or widening the perspective considered in policy...... assessments of ethically relevant concerns for animals. This has provided a scientific rigour that has helped to overcome controversies and allowed debates to move forward according to generally agreed methodologies. However, this focus can lead to policies leaving out other important issues relevant...

  1. It matters how old you feel: Antecedents and performance consequences of average relative subjective age in organizations.

    Science.gov (United States)

    Kunze, Florian; Raes, Anneloes M L; Bruch, Heike

    2015-09-01

    This article extends the conceptual knowledge of average relative subjective age in organizations by exploring organizational-level antecedents and consequences of employees, on average, feeling younger than their chronological age. We draw from the theories of selection-optimization-compensation and socioemotional selectivity to build a theoretical framework for relative subjective age in organizations. We hypothesize that companies in which employees, on average, perceive themselves to be younger than they actually are have a higher average individual goal accomplishment and, in turn, experience higher company performance. We further hypothesize that employees' average experience of high work-related meaning relates to a lower subjective age in organizations. In addition, we assess the role of environmental dynamism and age-inclusive human resource management as moderators in this theoretical model. Through empirically testing this model in a multisource dataset, including 107 companies with 15,164 participating employees, we received support for the hypothesized relationships. Our results contribute to current debates in the scientific literature on age and have important practical implications in light of the demographic changes faced by many companies. This research indicates to both researchers and practitioners that it is not employees' chronological age but their subjective age, a factor that can be influenced, which drives organizational performance outcomes. (c) 2015 APA, all rights reserved).

  2. The effect of productive classroom talk and metacommunication on young children's oral communicative competence and subject matter knowledge: An intervention study in early childhood education

    NARCIS (Netherlands)

    van der Veen, C.; de Mey, J.R.P.B.; van Kruistum, C.J.; van Oers, B.

    The aim of the present study was to investigate the effect of productive classroom talk and metacommunication on the development of young children's oral communicative competence and subject matter knowledge. This study can be characterized as a quasi-experimental study with a

  3. A Case Study of Beginning Science Teachers' Subject Matter (SMK) and Pedagogical Content Knowledge (PCK) of Teaching Chemical Reaction in Turkey

    Science.gov (United States)

    Usak, Muhammet; Ozden, Mustafa; Eilks, Ingo

    2011-01-01

    This paper describes a case study focusing on the subject matter knowledge, pedagogical content knowledge, and beliefs about science teaching of student teachers in Turkey at the start of their university education. The topic of interest was that of teaching chemical reactions in secondary chemistry education. A written test was developed which…

  4. Exploring the Relationship between Secondary Science Teachers' Subject Matter Knowledge and Knowledge of Student Conceptions While Teaching Evolution by Natural Selection

    Science.gov (United States)

    Lucero, Margaret M.; Petrosino, Anthony J.; Delgado, Cesar

    2017-01-01

    The fundamental scientific concept of evolution occurring by natural selection is home to many deeply held alternative conceptions and considered difficult to teach. Science teachers' subject matter knowledge (SMK) and the pedagogical content knowledge (PCK) component of knowledge of students' conceptions (KOSC) can be valuable resources for…

  5. Is Practical Subject Matter Knowledge Still Important? Examining the Siedentopian Perspective on the Role of Content Knowledge in Physical Education Teacher Education

    Science.gov (United States)

    Herold, Frank; Waring, Michael

    2017-01-01

    Background: The role that content knowledge, an important component of practical subject matter knowledge, plays for pre-service teachers (PSTs) in physical education teacher education (PETE) remains contested and unclear. Whilst some researchers emphasise the facilitative nature of such knowledge, others criticise that too much focus on content…

  6. Does Variation in the Extent of Generalized Trust, Individual Education and Extensiveness of Social Security Policies Matter for Maximization of Subjective Well-Being?

    Science.gov (United States)

    Valeeva, Rania F.

    2016-01-01

    In this paper, I examine whether generalized trust and education, as well as social security policies of welfare state institutions matter for cross-national differences in subjective well-being (SWB), because knowledge on this issue is still lacking. For this purpose I integrated the insights of two sociological theories: Social Function…

  7. The lifetime prevalence, health services utilization and risk of suicide of bipolar spectrum subjects, including subthreshold categories in the São Paulo ECA study.

    Science.gov (United States)

    Moreno, Doris Hupfeld; Andrade, Laura Helena

    2005-08-01

    Identifying the bipolar (BP) spectrum, including the classic Bipolar I subtype (BP-I), Bipolar II (BP-II) and subthreshold bipolar disorders not meeting DSM-IV diagnostic criteria has raised growing interest, as these softer expressions of bipolar spectrum have been underdiagnosed in spite of clinical consequences. Data are from the Sao Paulo Epidemiological Catchment Area Study (N=1464). Non-affective controls were compared to BP spectrum groups, based on DSM-IIIR and on the "clinical significance" criteria: Subsyndromal Hypomania (SSH) and Manic Symptoms (MS). The lifetime prevalence of BP subgroups was 8.3% (N=122). All BP-I and -II and around 75% of SSH and MS subjects had a lifetime depressive syndrome. Compared to controls and MS subjects, BP-I, BP-II and SSH groups searched more medical help and mental health services. SSH group displayed higher rates of clinical significance than BP-I subjects, and suicidality was higher in BP groups compared to controls. Even the softer MS group had higher rate of suicide attempts than SSH subjects. This is a cross-sectional study and interviews were conducted by lay personnel. Replication in bigger community samples using a mood spectrum approach is necessary to confirm these findings. However, our findings were very similar to those obtained by other authors. Softer expressions of BP disorders appear in 6.6% of this community sample and have serious clinical consequences, which supports the importance of including these categories in the BP spectrum.

  8. Location of lacunar infarcts correlates with cognition in a sample of non-disabled subjects with age-related white-matter changes: the LADIS study

    DEFF Research Database (Denmark)

    Benisty, S; Gouw, A A; Porcher, R

    2009-01-01

    in the following areas: lobar white matter, putamen/pallidum, thalamus, caudate nucleus, internal/external capsule, infratentorial areas. An analysis of covariance was performed after adjustment for possible confounders. RESULTS: Among 633 subjects, 47% had at least one lacune (31% at least one within basal...... a significant negative association between the presence of lacunes in putamen/pallidum and the memory compound Z score (beta = -0.13; p = 0.038). By contrast, no significant negative association was found between cognitive parameters and the presence of lacunes in internal capsule, lobar white matter...

  9. Evaluation of P300 components for emotion-loaded visual event-related potential in elderly subjects, including those with dementia.

    Science.gov (United States)

    Asaumi, Yasue; Morita, Kiichiro; Nakashima, Youko; Muraoka, Akemi; Uchimura, Naohisa

    2014-07-01

    In the present study, the P300 component of the emotion-loaded visual event-related potential in response to photographs of babies crying or smiling was measured to evaluate cognitive function in elderly subjects, including those with dementia. The subjects were 48 elderly people who consulted a memory disorder clinic. The visual event-related potential was measured using oddball tasks. Brain waves were recorded from four sites. We analyzed the P300 amplitude and latency. Subjects were divided into three groups (the dementia with Alzheimer's disease group [ADG]; the intermediate group [MG], and the healthy group [HG]) based on the Revised Hasegawa Dementia Scale, Mini-mental State Examination scores and the Clinical Dementia Rating. For all subjects, there was a significant positive correlation between P300 latency and Z-score of voxel-based specific regional analysis for Alzheimer's disease for crying or smiling faces. There was a negative correlation between P300 amplitude and Z-score for the crying face. MG subjects were divided into two groups (high risk: HRMG, low risk: LRMG) based on Z-scores (HRMG ≥ 2.0). The P300 amplitude of ADG was significantly smaller than that of HG, and the P300 latency of ADG was significantly longer than those of other groups for crying or smiling faces. The P300 latency of HRMG was significantly longer than that of LRMG for the smiling face. Furthermore, the P300 latency for the crying face was significantly shorter than that for the smiling face in HG and ADG. These findings suggest that analysis of P300 components of the emotion-loaded visual event-related potential may be a useful neuropsychological index for the diagnosis of Alzheimer's disease and high-risk subjects. © 2014 The Authors. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology.

  10. Perfection of methods of training to the technics of throws and catching of gymnastic subject matters at a stage of special base preparation.

    Directory of Open Access Journals (Sweden)

    Andreeva N.O.

    2011-08-01

    Full Text Available The analysis of performances gymnasts at competitions of a different level shows, that the system of training in rhythmic gymnastics at a stage of special-purpose base preparation requires entering of the corrective amendments which have been directed on perfection of its forms and procedures. One of such innovations may be use in training process of innovative methods of perfection of work on gymnastic subject matters. In article initial theoretical positions and ways of perfection of process of training to throws and catching of a ball and other subject matters as basic means of progress at gymnasts impellent qualities and the skills necessary for achievement of high results in competitive activity are considered.

  11. Assessing blood brain barrier dynamics or identifying or measuring selected substances, including ethanol or toxins, in a subject by analyzing Raman spectrum signals

    Science.gov (United States)

    Lambert, James L. (Inventor); Borchert, Mark S. (Inventor)

    2008-01-01

    A non-invasive method for analyzing the blood-brain barrier includes obtaining a Raman spectrum of a selected portion of the eye and monitoring the Raman spectrum to ascertain a change to the dynamics of the blood brain barrier.Also, non-invasive methods for determining the brain or blood level of an analyte of interest, such as glucose, drugs, alcohol, poisons, and the like, comprises: generating an excitation laser beam at a selected wavelength (e.g., at a wavelength of about 400 to 900 nanometers); focusing the excitation laser beam into the anterior chamber of an eye of the subject so that aqueous humor, vitreous humor, or one or more conjunctiva vessels in the eye is illuminated; detecting (preferably confocally detecting) a Raman spectrum from the illuminated portion of the eye; and then determining the blood level or brain level (intracranial or cerebral spinal fluid level) of an analyte of interest for the subject from the Raman spectrum. In certain embodiments, the detecting step may be followed by the step of subtracting a confounding fluorescence spectrum from the Raman spectrum to produce a difference spectrum; and determining the blood level and/or brain level of the analyte of interest for the subject from that difference spectrum, preferably using linear or nonlinear multivariate analysis such as partial least squares analysis. Apparatus for carrying out the foregoing methods are also disclosed.

  12. Small Ubiquitin-Like Modifier 4 (SUMO4 Gene M55V Polymorphism and Type 2 Diabetes Mellitus: A Meta-analysis Including 6,823 Subjects

    Directory of Open Access Journals (Sweden)

    Yan-yan Li

    2017-11-01

    Full Text Available BackgroundMany studies suggest that the small ubiquitin-like modifier 4 (SUMO4 M55V gene polymorphism (rs237025 may be associated with an increased risk of type 2 diabetes mellitus (T2DM. However, due to other conflicting results, a clear consensus is lacking in the matter.Objective and methodsA meta-analysis consisting of 6,823 subjects from 10 studies was conducted to elucidate relationship between the SUMO4 M55V gene polymorphism and T2DM. Depending on the heterogeneity of the data, either a fixed or random-effects model would be used to assess the combined odds ratio (ORs and their corresponding 95% confidence interval (CI.ResultsSUMO4 gene M55V polymorphism was significantly associated with T2DM in the whole population under allelic (OR: 1.18, 95% CI: 1.10–1.28, P = 1.63 × 10−5, recessive (OR: 1.59, 95% CI: 1.14–2.23, P = 0.006, dominant (OR: 0.815, 95% CI: 0.737–0.901, P = 6.89 × 10−5, homozygous (OR: 1.415, 95% CI: 1.170–1.710, P = 0.0003, heterozygous (OR: 1.191, 95% CI: 1.072–1.323, P = 0.001, and additive genetic models (OR: 1.184, 95% CI: 1.097–1.279, P = 1.63 × 10−5. In our subgroup analysis, a significant association was found again in the Chinese population, but not in Japanese or Iranian population.ConclusionSUMO4 gene M55V polymorphism may correlate with increased T2DM risk. Chinese carriers of the V allele of the SUMO4 gene M55V polymorphism may be predisposed to developing T2DM.

  13. Effect of dimethyl fumarate on gray and white matter pathology in subjects with relapsing multiple sclerosis: a longitudinal study.

    Science.gov (United States)

    Zivadinov, R; Hagemeier, J; Bergsland, N; Tavazzi, E; Weinstock-Guttman, B

    2018-03-01

    Dimethyl fumarate (DMF) is an oral treatment for relapsing-remitting multiple sclerosis (MS) with anti-inflammatory and possible neuroprotective properties. Its effect on white matter and gray matter pathology is still not fully understood. The aim of the study was to characterize the effect of DMF on normal-appearing white matter (NAWM) and thalamic pathology longitudinally. In this observational, longitudinal, 24-month magnetic resonance imaging study, 75 patients with relapsing-remitting MS treated with DMF and 40 age- and sex-matched healthy individuals were enrolled. Regional diffusion tensor imaging metrics and tract-based spatial statistics analyses were used to assess differences between groups. Mean diffusivity, axial diffusivity, radial diffusivity and fractional anisotropy were measured in the thalamus and NAWM. Baseline differences and changes over time were evaluated within and between study groups. At baseline, patients with MS showed significantly increased diffusivity and decreased fractional anisotropy in the thalamus (P < 0.001 for mean diffusivity, axial diffusivity and radial diffusivity) and NAWM (all P < 0.016) compared with healthy individuals. No significant within-group difference was found in diffusion tensor imaging measures over 24 months in either group. Healthy individuals showed a significantly greater rate of increased diffusivity parameters in the thalamus and NAWM compared with patients with MS, over 24 months (P < 0.05). The lack of changes in diffusion tensor imaging metrics in patients with MS over 24 months possibly indicates a neuroprotective role of DMF. These findings provide additional evidence of the beneficial effect of DMF on MS-related pathology. © 2018 EAN.

  14. Assessment of five different guideline indication criteria for spirometry, including modified GOLD criteria, in order to detect COPD: data from 5,315 subjects in the PLATINO study.

    Science.gov (United States)

    Luize, Ana P; Menezes, Ana Maria B; Perez-Padilla, Rogelio; Muiño, Adriana; López, Maria Victorina; Valdivia, Gonzalo; Lisboa, Carmem; Montes de Oca, Maria; Tálamo, Carlos; Celli, Bartolomé; Nascimento, Oliver A; Gazzotti, Mariana R; Jardim, José R

    2014-10-30

    Spirometry is the gold standard for diagnosing chronic obstructive pulmonary disease (COPD). Although there are a number of different guideline criteria for deciding who should be selected for spirometric screening, to date it is not known which criteria are the best based on sensitivity and specificity. Firstly, to evaluate the proportion of subjects in the PLATINO Study that would be recommended for spirometry testing according to Global initiative for Obstructive Lung Disease (GOLD)-modified, American College of Chest Physicians (ACCP), National Lung Health Education Program (NLHEP), GOLD and American Thoracic Society/European Respiratory Society (ATS/ERS) criteria. Secondly, we aimed to compare the sensitivity, specificity, and positive predictive and negative predictive values, of these five different criteria. Data from the PLATINO study included information on respiratory symptoms, smoking and previous spirometry testing. The GOLD-modified spirometry indication criteria are based on three positive answers out of five questions: the presence of cough, phlegm in the morning, dyspnoea, age over 40 years and smoking status. Data from 5,315 subjects were reviewed. Fewer people had an indication for spirometry (41.3%) according to the GOLD-modified criteria, and more people had an indication for spirometry (80.4%) by the GOLD and ATS/ERS criteria. A low percentage had previously had spirometry performed: GOLD-modified (14.5%); ACCP (13.2%); NLHEP (12.6%); and GOLD and ATS/ERS (12.3%). The GOLD-modified criteria showed the least sensitivity (54.9) and the highest specificity (61.0) for detecting COPD, whereas GOLD and ATS/ERS criteria showed the highest sensitivity (87.9) and the least specificity (20.8). There is a considerable difference in the indication for spirometry according to the five different guideline criteria. The GOLD-modified criteria recruit less people with the greatest sum of sensitivity and specificity.

  15. Molecular and structural characterization of dissolved organic matter from the deep ocean by FTICR-MS, including hydrophilic nitrogenous organic molecules

    Science.gov (United States)

    Reemtsma, T.; These, A.; Linscheid, M.; Leenheer, J.; Spitzy, A.

    2008-01-01

    Dissolved organic matter isolated from the deep Atlantic Ocean and fractionated into a so-called hydrophobic (HPO) fraction and a very hydrophilic (HPI) fraction was analyzed for the first time by Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS) to resolve the molecular species, to determine their exact masses, and to calculate their molecular formulas. The elemental composition of about 300 molecules was identified. Those in the HPO fraction (14C age of 5100 year) are very similar to much younger freshwater fulvic acids, but less aromatic and more oxygenated molecules are more frequent. This trend continues toward the HPI fraction and may indicate biotic and abiotic aging processes that this material experienced since its primary production thousands of years ago. In the HPI fraction series of nitrogenous molecules containing one, two, or three nitrogens were identified by FTICR-MS. Product ion spectra of the nitrogenous molecules suggest that the nitrogen atoms in these molecules are included in the (alicyclic) backbone of these molecules, possibly in reduced form. These mass spectrometric data suggest that a large set of stable fulvic acids is ubiquitous in all aquatic compartments. Although sources may differ, their actual composition and structure appears to be quite similar and largely independent from their source, because they are the remainder of intensive oxidative degradation processes. ?? 2008 American Chemical Society.

  16. Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS Study

    DEFF Research Database (Denmark)

    Jokinen, Hanna; Ryberg, Charlotte; Kalska, Hely

    2007-01-01

    , attention and executive functions in subjects with age-related white matter hyperintensities (WMH). METHODS: In the Leukoaraiosis and Disability Study, 567 subjects with age-related WMH were examined with a detailed neuropsychological assessment and quantitative magnetic resonance imaging. The relationships...... processing--namely, trail making A and Stroop test parts I and II. Anterior, but not posterior, corpus callosum atrophy was associated with deficits of attention and executive functions as reflected by the symbol digit modalities and digit cancellation tests, as well as by the subtraction scores in the trail...... is related to the frontal-lobe-mediated executive functions and attention, whereas overall corpus callosum atrophy is associated with the slowing of processing speed. Udgivelsesdato: 2007-May...

  17. Single-subject gray matter graph properties and their relationship with cognitive impairment in early- and late-onset Alzheimer's disease.

    Science.gov (United States)

    Tijms, Betty M; Yeung, Hiu M; Sikkes, Sietske A M; Möller, Christiane; Smits, Lieke L; Stam, Cornelis J; Scheltens, Philip; van der Flier, Wiesje M; Barkhof, Frederik

    2014-06-01

    Abstract We investigated the relationships between gray matter graph properties and cognitive impairment in a sample of 215 patients with Alzheimer's disease (AD) and also whether age of disease onset modifies such relationships. We expected that more severe cognitive impairment in AD would be related to more random graph topologies. Single-subject gray matter graphs were constructed from T1-weighted magnetic resonance imaging scans. The following global and local graph properties were calculated: betweenness centrality, normalized clustering coefficient γ, and normalized path length λ. Local clustering, path length, and betweenness centrality measures were determined for 90 anatomically defined areas. Regression models with as interaction term age of onset (i.e., early onset when patients were ≤65 years old and late onset when they were >65 years old at the time of diagnosis)×graph property were used to assess the relationships between cognitive functioning in five domains (memory, language, visuospatial, attention, and executive). Worse cognitive impairment was associated with more random graphs, as indicated by low γ, λ, and betweenness centrality values. Three interaction effects for age of onset×global graph property were found: Low γ and λ values more strongly related to memory impairment in early-onset patients; low beta values were significantly related to impaired visuospatial functioning in late-onset patients. For the local graph properties, language impairment showed the strongest relationship with decreased clustering coefficient in the left superior temporal gyrus across the entire sample. Our study shows that single-subject gray matter graph properties are associated with individual differences in cognitive impairment.

  18. Computer-Based Instruction: Effect of Cognitive Style, Instructional Format, and Subject-Matter Content on Learning

    Science.gov (United States)

    1990-04-01

    for this study. The test consists of 10 pairs of words (see Appendix B), ranked from easy to hard, selected from the Weschler Paired Associate Learning...facts and opinions on a current affairs topic. The decision-making task involved a maze problem. Subjects were tested immediately after training, 2...Screening Measures for Cognitive Style ........................ 5 The 4-Mat Test ......................................... 5 The Lateral Preference Test

  19. Investigation of Psychophysiological and Subjective Effects of Long Working Hours – Do Age and Hearing Impairment Matter?

    Directory of Open Access Journals (Sweden)

    Verena Wagner-Hartl

    2018-01-01

    Full Text Available Following current prognosis, demographic development raises expectations of an aging of the working population. Therefore, keeping employees healthy and strengthening their ability to work, becomes more and more important. When employees become older, dealing with age-related impairments of sensory functions, such as hearing impairment, is a central issue. Recent evidence suggests that negative effects that are associated with reduced hearing can have a strong impact at work. Especially under exhausting working situations such as working overtime hours, age and hearing impairment might influence employees’ well-being. Until now, neither the problem of aged workers and long working hours, nor the problem of hearing impairment and prolonged working time has been addressed explicitly. Therefore, a laboratory study was examined to answer the research question: Do age and hearing impairment have an impact on psychophysiological and subjective effects of long working hours. In total, 51 white-collar workers, aged between 24 and 63 years, participated in the laboratory study. The results show no significant effects for age and hearing impairment on the intensity of subjective consequences (perceived recovery and fatigue, subjective emotional well-being and physical symptoms of long working hours. However, the psychophysiological response (the saliva cortisol level to long working hours differs significantly between hearing impaired and normal hearing employees. Interestingly, the results suggest that from a psychophysiological point of view long working hours were more demanding for normal hearing employees.

  20. Measurement of area and personal breathing zone concentrations of diesel particulate matter (DPM) during oil and gas extraction operations, including hydraulic fracturing.

    Science.gov (United States)

    Esswein, Eric J; Alexander-Scott, Marissa; Snawder, John; Breitenstein, Michael

    2018-01-01

    Diesel engines serve many purposes in modern oil and gas extraction activities. Diesel particulate matter (DPM) emitted from diesel engines is a complex aerosol that may cause adverse health effects depending on exposure dose and duration. This study reports on personal breathing zone (PBZ) and area measurements for DPM (expressed as elemental carbon) during oil and gas extraction operations including drilling, completions (which includes hydraulic fracturing), and servicing work. Researchers at the National Institute for Occupational Safety and Health (NIOSH) collected 104 full-shift air samples (49 PBZ and 55 area) in Colorado, North Dakota, Texas, and New Mexico during a four-year period from 2008-2012. The arithmetic mean (AM) of the full shift TWA PBZ samples was 10 µg/m3; measurements ranged from 0.1-52 µg/m3. The geometric mean (GM) for the PBZ samples was 7 µg/m3. The AM of the TWA area measurements was 17 µg/m3 and ranged from 0.1-68 µg/m3. The GM for the area measurements was 9.5 µg/m3. Differences between the GMs of the PBZ samples and area samples were not statistically different (P > 0.05). Neither the Occupational Safety and Health Administration (OSHA), NIOSH, nor the American Conference of Governmental Industrial Hygienists (ACGIH) have established occupational exposure limits (OEL) for DPM. However, the State of California, Department of Health Services lists a time-weighted average (TWA) OEL for DPM as elemental carbon (EC) exposure of 20 µg/m3. Five of 49 (10.2%) PBZ TWA measurements exceeded the 20 µg/m3 EC criterion. These measurements were collected on Sandmover and Transfer Belt (T-belt) Operators, Blender and Chemical Truck Operators, and Water Transfer Operators during hydraulic fracturing operations. Recommendations to minimize DPM exposures include elimination (locating diesel-driven pumps away from well sites), substitution, (use of alternative fuels), engineering controls using advanced emission control technologies

  1. Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with Adult Treatment Panel III criteria in nonobese nondiabetic subjects

    National Research Council Canada - National Science Library

    Musso, Giovanni; Gambino, Roberto; Bo, Simona; Uberti, Barbara; Biroli, Giampaolo; Pagano, Gianfranco; Cassader, Maurizio

    2008-01-01

    The ability of the Adult Treatment Panel III (ATP III) criteria of metabolic syndrome to identify insulin-resistant subjects at increased cardiovascular risk is suboptimal, especially in the absence of obesity and diabetes...

  2. Prevention of urinary tract infections with vitamin D supplementation 20,000 IU per week for five years. Results from an RCT including 511 subjects.

    Science.gov (United States)

    Jorde, Rolf; Sollid, Stina T; Svartberg, Johan; Joakimsen, Ragnar M; Grimnes, Guri; Hutchinson, Moira Y S

    2016-01-01

    In observational studies vitamin D deficiency is associated with increased risk of infections, whereas the effect of vitamin D supplementation in randomized controlled trials is non-conclusive. Five hundred and eleven subjects with prediabetes were randomized to vitamin D3 (20,000 IU per week) versus placebo for five years. Every sixth month, a questionnaire on respiratory tract infections (RTI) (common cold, bronchitis, influenza) and urinary tract infection (UTI) was filled in. Mean baseline serum 25-hydroxyvitamin D (25(OH)D) level was 60 nmol/L. Two hundred and fifty-six subjects received vitamin D and 255 placebo. One hundred and sixteen subjects in the vitamin D and 111 in the placebo group completed the five-year study. Eighteen subjects in the vitamin D group and 34 subjects in the placebo group reported UTI during the study (p vitamin D on UTI was unrelated to baseline serum 25(OH)D level. Supplementation with vitamin D might prevent UTI, but confirmatory studies are needed.

  3. Solid Matter

    CERN Document Server

    Angelo, Joseph A

    2011-01-01

    Supported by a generous quantity of full-color illustrations and interesting sidebars, Solid Matter introduces the basic characteristics and properties of solid matter. It briefly describes the cosmic connection of the elements, leading readers through several key events in human pre-history that resulted in more advanced uses of matter in the solid state. Chapters include:. -Solid Matter: An Initial Perspective. -Physical Behavior of Matter. -The Gravity of Matter. -Fundamentals of Materials Science. -Rocks and Minerals. -Metals. -Building Materials. -Carbon Earth's Most Versatile Element. -S

  4. Should nonalcoholic fatty liver disease be included in the definition of metabolic syndrome? A cross-sectional comparison with Adult Treatment Panel III criteria in nonobese nondiabetic subjects.

    Science.gov (United States)

    Musso, Giovanni; Gambino, Roberto; Bo, Simona; Uberti, Barbara; Biroli, Giampaolo; Pagano, Gianfranco; Cassader, Maurizio

    2008-03-01

    The ability of the Adult Treatment Panel III (ATP III) criteria of metabolic syndrome to identify insulin-resistant subjects at increased cardiovascular risk is suboptimal, especially in the absence of obesity and diabetes. Nonalcoholic fatty liver disease (NAFLD) is associated with insulin resistance and is emerging as an independent cardiovascular risk factor. We compared the strength of the associations of ATP III criteria and of NAFLD to insulin resistance, oxidative stress, and endothelial dysfunction in nonobese nondiabetic subjects. Homeostasis model assessment of insulin resistance (HOMA-IR) >2, oxidative stress (nitrotyrosine), soluble adhesion molecules (intracellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin), and circulating adipokines (tumor necrosis factor-alpha, leptin, adiponectin, and resistin) were cross-sectionally correlated to ATP III criteria and to NAFLD in 197 unselected nonobese nondiabetic subjects. NAFLD more accurately predicted insulin resistance than ATP III criteria: sensitivity 73 vs. 38% (P = 0.0001); positive predictive value: 81 vs. 62% (P = 0.035); negative predictive value 87 vs. 74% (P = 0.012); positive likelihood ratio 4.39 vs. 1.64 (P = 0.0001); and negative likelihood ratio 0.14 vs. 0.35 (P = 0.0001). Adding NAFLD to ATP III criteria significantly improved their diagnostic accuracy for insulin resistance. Furthermore, NAFLD independently predicted HOMA-IR, nitrotyrosine, and soluble adhesion molecules on logistic regression analysis; the presence of NAFLD entailed more severe oxidative stress and endothelial dysfunction, independent of adiposity or any feature of the metabolic syndrome in insulin-resistant subjects. NAFLD is more tightly associated with insulin resistance and with markers of oxidative stress and endothelial dysfunction than with ATP III criteria in nonobese nondiabetic subjects and may help identify individuals with increased cardiometabolic risk in this population.

  5. Use of a multi-isotope and multi-tracer approach including organic matter isotopes for quantifying nutrient contributions from agricultural vs wastewater sources

    Science.gov (United States)

    Kendall, C.; Silva, S. R.; Young, M. B.

    2013-12-01

    While nutrient isotopes are a well-established tool for quantifying nutrients inputs from agricultural vs wastewater treatment plant (WWTP) sources, we have found that combining nutrient isotopes with the C, N, and S isotopic compositions of dissolved and particulate organic matter, as part of a comprehensive multi-isotope and multi-tracer approach, is a much more diagnostic approach. The main reasons why organic matter C-N-S isotopes are a useful adjunct to studies of nutrient sources and biogeochemical processes are that the dissolved and particulate organic matter associated with (1) different kinds of animals (e.g., humans vs cows) often have distinctive isotopic compositions reflecting the different diets of the animals, and (2) the different processes associated with the different land uses (e.g., in the WWTP or associated with different crop types) often result in significant differences in the isotopic compositions of the organics. The analysis of the δ34S of particulate organic matter (POM) and dissolved organic matter (DOM) has been found to be especially useful for distinguishing and quantifying water, nutrient, and organic contributions from different land uses in aquatic systems where much of the organic matter is aquatic in origin. In such environments, the bacteria and algae incorporate S from sulfate and sulfide that is isotopically labeled by the different processes associated with different land uses. We have found that there is ~35 permil range in δ34S of POM along the river-estuary continuum in the San Joaquin/Sacramento River basin, with low values associated with sulfate reduction in the upstream wetlands and high values associated with tidal inputs of marine water into the estuary. Furthermore, rice agriculture results in relatively low δ34S values whereas WWTP effluent in the Sacramento River produces distinctly higher values than upstream of the WWTP, presumably because SO2 is used to treat chlorinated effluent. The fish living

  6. Chern-Simons Theories with Fundamental Matter: A Brief Review of Large N Results Including Fermi-Bose Duality and the S-matrix

    Science.gov (United States)

    Wadia, Spenta R.

    We begin with a few words about Salam's contribution to the growth of String Theory in India. In the technical talk we review results in SU(N) Chern-Simons plus vector matter theories in 2+1 dim in the large N limit. The dressing of charged matter by Chern-Simons gauge fields leads to anyons that interpolate between fermions and bosons and lead to a duality symmetry between fermionic and bosonic theories. The S-matrix (defined in the large N limit) besides exhibiting this duality, also exhibits novel properties due to the presence of anyons. The S-matrix is not analytic, like in Aharonov-Bohm scattering, and satisfies modified crossing symmetry relations.

  7. Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast

    DEFF Research Database (Denmark)

    Nilsson, Anne C; Ostman, Elin M; Holst, Jens Juul

    2008-01-01

    tolerance and related variables after a subsequent standardized breakfast in healthy subjects (n = 15). At breakfast, blood was sampled for 3 h for analysis of blood glucose, serum insulin, serum FFA, serum triacylglycerides, plasma glucagon, plasma gastric-inhibitory peptide, plasma glucagon-like peptide-1...... (GLP-1), serum interleukin (IL)-6, serum IL-8, and plasma adiponectin. Satiety was subjectively rated after breakfast and the gastric emptying rate (GER) was determined using paracetamol as a marker. Breath hydrogen was measured as an indicator of colonic fermentation. Evening meals with barley kernel......-kernel bread compared with WWB. Breath hydrogen correlated positively with satiety (r = 0.27; P metabolic risk variables at breakfast...

  8. Predictive Utility of Marketed Volumetric Software Tools in Subjects at Risk for Alzheimer Disease: Do Regions Outside the Hippocampus Matter?

    Science.gov (United States)

    Tanpitukpongse, T P; Mazurowski, M A; Ikhena, J; Petrella, J R

    2017-03-01

    Alzheimer disease is a prevalent neurodegenerative disease. Computer assessment of brain atrophy patterns can help predict conversion to Alzheimer disease. Our aim was to assess the prognostic efficacy of individual-versus-combined regional volumetrics in 2 commercially available brain volumetric software packages for predicting conversion of patients with mild cognitive impairment to Alzheimer disease. Data were obtained through the Alzheimer's Disease Neuroimaging Initiative. One hundred ninety-two subjects (mean age, 74.8 years; 39% female) diagnosed with mild cognitive impairment at baseline were studied. All had T1-weighted MR imaging sequences at baseline and 3-year clinical follow-up. Analysis was performed with NeuroQuant and Neuroreader. Receiver operating characteristic curves assessing the prognostic efficacy of each software package were generated by using a univariable approach using individual regional brain volumes and 2 multivariable approaches (multiple regression and random forest), combining multiple volumes. On univariable analysis of 11 NeuroQuant and 11 Neuroreader regional volumes, hippocampal volume had the highest area under the curve for both software packages (0.69, NeuroQuant; 0.68, Neuroreader) and was not significantly different ( P > .05) between packages. Multivariable analysis did not increase the area under the curve for either package (0.63, logistic regression; 0.60, random forest NeuroQuant; 0.65, logistic regression; 0.62, random forest Neuroreader). Of the multiple regional volume measures available in FDA-cleared brain volumetric software packages, hippocampal volume remains the best single predictor of conversion of mild cognitive impairment to Alzheimer disease at 3-year follow-up. Combining volumetrics did not add additional prognostic efficacy. Therefore, future prognostic studies in mild cognitive impairment, combining such tools with demographic and other biomarker measures, are justified in using hippocampal volume as

  9. Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast.

    Science.gov (United States)

    Nilsson, Anne C; Ostman, Elin M; Holst, Jens J; Björck, Inger M E

    2008-04-01

    Low-glycemic index (GI) foods and foods rich in whole grain are associated with reduced risk of type 2 diabetes and cardiovascular disease. We studied the effect of cereal-based bread evening meals (50 g available starch), varying in GI and content of indigestible carbohydrates, on glucose tolerance and related variables after a subsequent standardized breakfast in healthy subjects (n = 15). At breakfast, blood was sampled for 3 h for analysis of blood glucose, serum insulin, serum FFA, serum triacylglycerides, plasma glucagon, plasma gastric-inhibitory peptide, plasma glucagon-like peptide-1 (GLP-1), serum interleukin (IL)-6, serum IL-8, and plasma adiponectin. Satiety was subjectively rated after breakfast and the gastric emptying rate (GER) was determined using paracetamol as a marker. Breath hydrogen was measured as an indicator of colonic fermentation. Evening meals with barley kernel based bread (ordinary, high-amylose- or beta-glucan-rich genotypes) or an evening meal with white wheat flour bread (WWB) enriched with a mixture of barley fiber and resistant starch improved glucose tolerance at the subsequent breakfast compared with unsupplemented WWB (P carbohydrates of the evening meal may affect glycemic excursions and related metabolic risk variables at breakfast through a mechanism involving colonic fermentation. The results provide evidence for a link between gut microbial metabolism and key factors associated with insulin resistance.

  10. Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study.

    Science.gov (United States)

    Hartvigsen, M L; Lærke, H N; Overgaard, A; Holst, J J; Bach Knudsen, K E; Hermansen, K

    2014-05-01

    Prospective studies have shown an inverse relationship between whole grain consumption and the risk of type 2 diabetes, where short chain fatty acids (SCFA) may be involved. Our objective was to determine the effect of isolated arabinoxylan alone or in combination with whole grain rye kernels on postprandial glucose, insulin, free fatty acids (FFA), gut hormones, SCFA and appetite in subjects with the metabolic syndrome (MetS). Fifteen subjects with MetS participated in this acute, randomised, cross-over study. The test meals each providing 50 g of digestible carbohydrate were as follows: semolina porridge added concentrated arabinoxylan (AX), rye kernels (RK) or concentrated arabinoxylan combined with rye kernels (AXRK) and semolina porridge as control (SE). A standard lunch was served 4 h after the test meals. Blood samples were drawn during a 6-h period, and appetite scores and breath hydrogen were assessed every 30 min. The AXRK meal reduced the acute glucose (P=0.005) and insulin responses (P<0.001) and the feeling of hunger (P=0.005; 0-360 min) compared with the control meal. The AX and AXRK meals increased butyrate and acetate concentrations after 6 h. No significant differences were found for the second meal responses of glucose, insulin, FFA, glucagon-like peptide-1 or ghrelin. Our results indicate a stimulatory effect of arabinoxylan on butyrate and acetate production, however, with no detectable effect on the second meal glucose response. It remains to be tested in a long-term study if a beneficial effect on the glucose response of the isolated arabinoxylan will be related to the SCFA production.

  11. Dark matter in galaxies

    OpenAIRE

    Zasov, A. V.; Saburova, A. S.; Khoperskov, A. V.; Khoperskov, S. A.

    2017-01-01

    Dark matter in galaxies, its abundance, and its distribution remain a subject of long-standing discussion, especially in view of the fact that neither dark matter particles nor dark matter bodies have yet been found. Experts' opinions range from a very large number of completely dark galaxies exist to nonbaryonic dark matter does not exist at all in any significant amounts. We discuss astronomical evidence for the existence of dark matter and its connection with visible matter and examine att...

  12. Train, teach; taught? How the content of specific science subject matter knowledge sessions impacts on trainee teachers’ classroom practice and children’s learning

    Directory of Open Access Journals (Sweden)

    Vanessa Kind

    2008-11-01

    Full Text Available The impact science sessions for trainee science teachers have on 11-14 year olds’ learning of science was assessed using questionnaires and a “Video-Interview (trainee –Interview (pupils” (V-I-I technique devised for this study. V-I-I involved: video-recording trainee-taught lessons; and two interviews – with a pupil group to probe learning occurring in the lesson and with the trainee.Eighty UK-based trainees taking a one-year postgraduate teacher education course completed the questionnaire probing perceptions about university- and school-based training sessions designed to develop science subject matter knowledge (SMK and pedagogical content knowledge (PCK. Six trainees participated in V-I-I.Most trainees saw all sessions as SMK-based, regardless of teacher educators’ intended purposes. Lesson videos revealed ”describing” activities, task completion and good behaviour as main focii. Explanation of key science ideas and use of materials and /ideas from training sessions were largely absent. Trainee interviews revealed contrasts: most perceived a lesson as “successful” when children completed tasks quietly. Other trainees realised their understanding impacted on pupils’ learning science concepts. Pupil interviews showed positive attitudes towards science and learning difficult ideas, but little specific learning of topics taught.

  13. A tale of three blind men on the proper subject matter of clinical science and practice: commentary on Plaud's behaviorism vs. Ilardi and Feldman's cognitive neuroscience.

    Science.gov (United States)

    Forsyth, J P; Kelly, M M

    2001-09-01

    Plaud (J Clin Psychol 57, 1089-1102, 1109-1111, 1119-1120) and Ilardi and Feldman (J Clin Psychol 57, 1067-1088, 1103-1107, 1113-1117, 1121-1124) argue for two very different approaches to clinical science and practice (i.e., behavior analysis and cognitive neuroscience, respectively). We comment on the assets and liabilities of both perspectives as presented and attempt to achieve some semblance of balance between the three protagonists embroiled in this current debate. The vision of clinical science we articulate is more ecumenical and evolutionary, rather than paradigmatic and revolutionary. As we see it, the problem clinical psychology faces is much larger than the authors let on; namely, how best to make clinical science meaningful and relevant to practitioners, consumers, the general public, and the behavioral health-care community. Clinical psychology's immediate internal problem is not pluralism with regard to subject matter, worldview, methodology, or school of thought, but pluralism in clinical psychologists' adherence to a scientific epistemology as the only legitimate form of clinical psychology. On this latter point, we still have a very long way to go. Copyright 2001 John Wiley & Sons, Inc.

  14. Benefits of multi-modal fusion analysis on a large-scale dataset: life-span patterns of inter-subject variability in cortical morphometry and white matter microstructure.

    Science.gov (United States)

    Groves, Adrian R; Smith, Stephen M; Fjell, Anders M; Tamnes, Christian K; Walhovd, Kristine B; Douaud, Gwenaëlle; Woolrich, Mark W; Westlye, Lars T

    2012-10-15

    Neuroimaging studies have become increasingly multimodal in recent years, with researchers typically acquiring several different types of MRI data and processing them along separate pipelines that provide a set of complementary windows into each subject's brain. However, few attempts have been made to integrate the various modalities in the same analysis. Linked ICA is a robust data fusion model that takes multi-modal data and characterizes inter-subject variability in terms of a set of multi-modal components. This paper examines the types of components found when running Linked ICA on a large magnetic resonance imaging (MRI) morphometric and diffusion tensor imaging (DTI) data set comprising 484 healthy subjects ranging from 8 to 85 years of age. We find several strong global features related to age, sex, and intracranial volume; in particular, one component predicts age to a high accuracy (r=0.95). Most of the remaining components describe spatially localized modes of variability in white or gray matter, with many components including both tissue types. The multimodal components tend to be located in anatomically-related brain areas, suggesting a morphological and possibly functional relationship. The local components show relationships between surface-based cortical thickness and arealization, voxel-based morphometry (VBM), and between three different DTI measures. Further, we report components related to artifacts (e.g. scanner software upgrades) which would be expected in a dataset of this size. Most of the 100 extracted components showed interpretable spatial patterns and were found to be reliable using split-half validation. This work provides novel information about normal inter-subject variability in brain structure, and demonstrates the potential of Linked ICA as a feature-extracting data fusion approach across modalities. This exploratory approach automatically generates models to explain structure in the data, and may prove especially powerful for large

  15. Condensed matter physics

    CERN Document Server

    Isihara, A

    2007-01-01

    More than a graduate text and advanced research guide on condensed matter physics, this volume is useful to plasma physicists and polymer chemists, and their students. It emphasizes applications of statistical mechanics to a variety of systems in condensed matter physics rather than theoretical derivations of the principles of statistical mechanics and techniques. Isihara addresses a dozen different subjects in separate chapters, each designed to be directly accessible and used independently of previous chapters. Topics include simple liquids, electron systems and correlations, two-dimensional

  16. When Matter Matters

    CERN Document Server

    Easson, Damien A.; Vikman, Alexander

    2013-07-10

    We study a recently proposed scenario for the early universe: Subluminal Galilean Genesis. We prove that without any other matter present in the spatially flat Friedmann universe, the perturbations of the Galileon scalar field propagate with a speed at most equal to the speed of light. This proof applies to all cosmological solutions -- to the whole phase space. However, in a more realistic situation, when one includes any matter which is not directly coupled to the Galileon, there always exists a region of phase space where these perturbations propagate superluminally, indeed with arbitrarily high speed. We illustrate our analytic proof with numerical computations. We discuss the implications of this result for the possible UV completion of the model.

  17. Gaseous Matter

    CERN Document Server

    Angelo, Joseph A

    2011-01-01

    aseous Matter focuses on the many important discoveries that led to the scientific interpretation of matter in the gaseous state. This new, full-color resource describes the basic characteristics and properties of several important gases, including air, hydrogen, helium, oxygen, and nitrogen. The nature and scope of the science of fluids is discussed in great detail, highlighting the most important scientific principles upon which the field is based. Chapters include:. Gaseous Matter An Initial Perspective. Physical Characteristics of Gases. The Rise of the Science of Gases. Kinetic Theory of

  18. The Role of Teachers' Pedagogical and Subject-Matter Knowledge in Planning and Enacting Science-Inquiry Instruction, and in Assessing Students' Science-Inquiry Learning

    Science.gov (United States)

    Birlean, Camelia

    This study explored the relation between pedagogical knowledge and subject-matter knowledge, in the context of inquiry-driven science instruction, and their relation to instructors' performance in the instructional process. This multiple case study focused on three distinct categories of teachers--Novice in Inquiry and in Science, Novice in Inquiry and Expert in Science, and Expert in Inquiry and in Science--and examined the commonalities and differences among them by exploring the cognitive processes these teachers used when planning and enacting an inquiry instructional situation, as well as when assessing students' learning resulting from this specific instructional event. Inquiry instruction varied across cases from largely structured to largely open. The Novice-Novice's science instruction, predominantly traditional in the approach, differed greatly from that of the Expert-Expert and of the Novice-Expert. The latter two emphasized--to various extents structured, guided, and open--inquiry strategy as part of their ongoing instruction. The open inquiry was an approach embraced solely by the Expert-Expert teacher throughout the Advanced Science Research instruction, emphasizing the creative aspect of problem generation. Edward teacher also distinguished himself from the other two participants in his view of planning and terminology used to describe it, both of which emphasized the dynamic and flexible feature of this instructional process. The Expert-Expert identified occasional planning, planning of specific skills and content critical to students' learning process during their independent inquiry. The observed teaching performance of the three participants partly reflected their planning; the alignment was least frequent for the Novice-Novice. The assessment of inquiry-based projects varied greatly across participants. Each teacher participant evaluated a set of three inquiry-based science projects that differed in their quality, and this variation increased

  19. Statistical physics including applications to condensed matter

    CERN Document Server

    Hermann, Claudine

    2005-01-01

    Statistical Physics bridges the properties of a macroscopic system and the microscopic behavior of its constituting particles, otherwise impossible due to the giant magnitude of Avogadro's number. Numerous systems of today's key technologies -- as e.g. semiconductors or lasers -- are macroscopic quantum objects; only statistical physics allows for understanding their fundamentals. Therefore, this graduate text also focuses on particular applications such as the properties of electrons in solids with applications, and radiation thermodynamics and the greenhouse effect.

  20. Dirac matter

    CERN Document Server

    Rivasseau, Vincent; Fuchs, Jean-Nöel

    2017-01-01

    This fifteenth volume of the Poincare Seminar Series, Dirac Matter, describes the surprising resurgence, as a low-energy effective theory of conducting electrons in many condensed matter systems, including graphene and topological insulators, of the famous equation originally invented by P.A.M. Dirac for relativistic quantum mechanics. In five highly pedagogical articles, as befits their origin in lectures to a broad scientific audience, this book explains why Dirac matters. Highlights include the detailed "Graphene and Relativistic Quantum Physics", written by the experimental pioneer, Philip Kim, and devoted to graphene, a form of carbon crystallized in a two-dimensional hexagonal lattice, from its discovery in 2004-2005 by the future Nobel prize winners Kostya Novoselov and Andre Geim to the so-called relativistic quantum Hall effect; the review entitled "Dirac Fermions in Condensed Matter and Beyond", written by two prominent theoreticians, Mark Goerbig and Gilles Montambaux, who consider many other mater...

  1. Solid-state 13C nuclear magnetic resonance spectroscopic characterization of soil organic matter fractions in a forest ecosystem subjected to prescribed burning and thinning

    Science.gov (United States)

    Prescribed burning and thinning are gaining popularity as low-cost forest protection measures. Such field management practices could alter the chemical properties of soil organic matter (SOM), especially humic substances. In this work, we collected surface soil samples from the Bankhead National For...

  2. Correlation between white matter damage and gray matter lesions in multiple sclerosis patients.

    Science.gov (United States)

    Han, Xue-Mei; Tian, Hong-Ji; Han, Zheng; Zhang, Ce; Liu, Ying; Gu, Jie-Bing; Bakshi, Rohit; Cao, Xia

    2017-05-01

    We observed the characteristics of white matter fibers and gray matter in multiple sclerosis patients, to identify changes in diffusion tensor imaging fractional anisotropy values following white matter fiber injury. We analyzed the correlation between fractional anisotropy values and changes in whole-brain gray matter volume. The participants included 20 patients with relapsing-remitting multiple sclerosis and 20 healthy volunteers as controls. All subjects underwent head magnetic resonance imaging and diffusion tensor imaging. Our results revealed that fractional anisotropy values decreased and gray matter volumes were reduced in the genu and splenium of corpus callosum, left anterior thalamic radiation, hippocampus, uncinate fasciculus, right corticospinal tract, bilateral cingulate gyri, and inferior longitudinal fasciculus in multiple sclerosis patients. Gray matter volumes were significantly different between the two groups in the right frontal lobe (superior frontal, middle frontal, precentral, and orbital gyri), right parietal lobe (postcentral and inferior parietal gyri), right temporal lobe (caudate nucleus), right occipital lobe (middle occipital gyrus), right insula, right parahippocampal gyrus, and left cingulate gyrus. The voxel sizes of atrophic gray matter positively correlated with fractional anisotropy values in white matter association fibers in the patient group. These findings suggest that white matter fiber bundles are extensively injured in multiple sclerosis patients. The main areas of gray matter atrophy in multiple sclerosis are the frontal lobe, parietal lobe, caudate nucleus, parahippocampal gyrus, and cingulate gyrus. Gray matter atrophy is strongly associated with white matter injury in multiple sclerosis patients, particularly with injury to association fibers.

  3. Gray and white matter changes in subjective cognitive impairment, amnestic mild cognitive impairment and Alzheimer's disease: a voxel-based analysis study.

    Directory of Open Access Journals (Sweden)

    Kuniaki Kiuchi

    Full Text Available Subjective cognitive impairment may be a very early at-risk period of the continuum of dementia. However, it is difficult to discriminate at-risk states from normal aging. Thus, detection of the early pathological changes in the subjective cognitive impairment period is needed. To elucidate these changes, we employed diffusion tensor imaging and volumetry analysis, and compared subjective cognitive impairment with normal, mild cognitive impairment and Alzheimer's disease. The subjects in this study were 39 Alzheimer's disease, 43 mild cognitive impairment, 28 subjective cognitive impairment and 41 normal controls. There were no statistically significant differences between the normal control and subjective cognitive impairment groups in all measures. Alzheimer's disease and mild cognitive impairment had the same extent of brain atrophy and diffusion changes. These results are consistent with the hypothetical model of the dynamic biomarkers of Alzheimer's disease.

  4. Low episodic memory performance in cognitively normal elderly subjects is associated with increased posterior cingulate gray matter N-acetylaspartate: a1H MRSI study at 7 Tesla.

    Science.gov (United States)

    Schreiner, Simon J; Kirchner, Thomas; Wyss, Michael; Van Bergen, Jiri M G; Quevenco, Frances C; Steininger, Stefanie C; Griffith, Erica Y; Meier, Irene; Michels, Lars; Gietl, Anton F; Leh, Sandra E; Brickman, Adam M; Hock, Christoph; Nitsch, Roger M; Pruessmann, Klaas P; Henning, Anke; Unschuld, Paul G

    2016-12-01

    Low episodic memory performance characterizes elderly subjects at increased risk for Alzheimer's disease (AD) and may reflect neuronal dysfunction within the posterior cingulate cortex and precuneus (PCP) region. To investigate a potential association between cerebral neurometabolism and low episodic memory in the absence of cognitive impairment, tissue-specific magnetic resonance spectroscopic imaging at ultrahigh field strength of 7 Tesla was used to investigate the PCP region in a healthy elderly study population (n = 30, age 70 ± 5.7 years, Mini-Mental State Examination 29.4 ± 4.1). The Verbal Learning and Memory Test (VLMT) was administered as part of a neuropsychological battery for assessment of episodic memory performance. Significant differences between PCP gray and white matter could be observed for glutamate-glutamine (p = 0.001), choline (p = 0.01), and myo-inositol (p = 0.02). Low Verbal Learning and Memory Test performance was associated with high N-acetylaspartate in PCP gray matter (p = 0.01) but not in PCP white matter. Our data suggest that subtle decreases in episodic memory performance in the elderly may be associated with increased levels of N-acetylaspartate as a reflection of increased mitochondrial energy capacity in PCP gray matter. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Respiratory effects of particulate matter air pollution: studies on diesel exhaust, road tunnel, subway and wood smoke exposure in human subjects

    Energy Technology Data Exchange (ETDEWEB)

    Sehlstedt, Maria

    2011-07-01

    Background: Ambient air pollution is associated with adverse health effects, but the sources and components, which cause these effects is still incompletely understood. The aim of this thesis was to investigate the pulmonary effects of a variety of common air pollutants, including diesel exhaust, biomass smoke, and road tunnel and subway station environments. Healthy non-smoking volunteers were exposed in random order to the specific air pollutants and air/control, during intermittent exercise, followed by bronchoscopy. Methods and results: In study I, exposures were performed with diesel exhaust (DE) generated at transient engine load and air for 1 hour with bronchoscopy at 6 hours post-exposure. Immunohistochemical analyses of bronchial mucosal biopsies showed that DE exposure significantly increased the endothelial adhesion molecule expression of p-selectin and VCAM-1, together with increased bronchoalveolar lavage (BAL) eosinophils. In study II, the subjects were exposed for 1 hour to DE generated during idling with bronchoscopy at 6 hours. The bronchial mucosal biopsies showed significant increases in neutrophils, mast cells and lymphocytes together with bronchial wash neutrophils. Additionally, DE exposure significantly increased the nuclear translocation of the aryl hydrocarbon receptor (AhR) and phosphorylated c-jun in the bronchial epithelium. In contrast, the phase II enzyme NAD(P)H-quinone oxidoreductase 1 (NQO1) decreased after DE. In study III, the 2-hour exposures took place in a road tunnel with bronchoscopy 14 hours later. The road tunnel exposure significantly increased the total numbers of lymphocytes and alveolar macrophages in BAL, whereas NK cell and CD56+/T cell numbers significantly decreased. Additionally, the nuclear expression of phosphorylated c-jun in the bronchial epithelium was significantly increased after road tunnel exposure. In study IV, the subjects were exposed to metal-rich particulate aerosol for 2 hours at a subway station

  6. New light on a dark subject: On the use of fluorescence data to deduce redox states of natural organic matter (NOM)

    Science.gov (United States)

    Macalady, Donald L.; Walton-Day, Katherine

    2009-01-01

    This paper reports the use of excitation-emission matrix fluorescence spectroscopy (EEMS), parallel factor statistical analysis (PARAFAC), and oxidation-reduction experiments to examine the effect of redox conditions on PARAFAC model results for aqueous samples rich in natural organic matter. Fifty-four aqueous samples from 11 different geographic locations and two plant extracts were analyzed untreated and after chemical treatments or irradiation were used in attempts to change the redox status of the natural organic matter. The EEMS spectra were generated and modeled using a PARAFAC package developed by Cory and McKnight (2005). The PARAFAC model output was examined for consistency with previously reported relations and with changes expected to occur upon experimental oxidation and reduction of aqueous samples. Results indicate the implied fraction of total sample fluorescence attributed to quinone-like moieties was consistent (0.64 to 0.78) and greater than that observed by Cory and McKnight (2005). The fraction of the quinone-like moieties that was reduced (the reducing index, RI) showed relatively little variation (0.46 to 0.71) despite attempts to alter the redox status of the natural organic matter. The RI changed little after reducing samples using zinc metal, oxidizing at high pH with air, or irradiating with a Xenon lamp. Our results, however, are consistent with the correlations between the fluorescence indices (FI) of samples and the ratio of PARAFAC fitting parameters suggested by Cory and McKnight (2005), though we used samples with a much narrower range of FI values.

  7. Interaction of radiation with matter

    CERN Document Server

    Nikjoo, Hooshang; Emfietzoglou, Dimitris

    2012-01-01

    Written for students approaching the subject for the first time, this text provides a solid grounding in the physics of the interactions of photons and particles with matter, which is the basis of radiological physics and radiation dosimetry. The authors first present the relevant atomic physics and then describe the interactions, emphasizing practical applications in health/medical physics and radiation biology. They cover such important topics as microdosimetry, interaction of photons with matter, electron energy loss, and dielectric response. Each chapter includes exercises and a summary.

  8. The white matter query language: a novel approach for describing human white matter anatomy.

    Science.gov (United States)

    Wassermann, Demian; Makris, Nikos; Rathi, Yogesh; Shenton, Martha; Kikinis, Ron; Kubicki, Marek; Westin, Carl-Fredrik

    2016-12-01

    We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method simplifies the quantification and statistical analysis of white matter tracts on large diffusion MRI databases. This work reflects the careful syntactical definition of major white matter fiber tracts in the human brain based on a neuroanatomist's expert knowledge. The framework is based on a novel query language with a near-to-English textual syntax. This query language makes it possible to construct a dictionary of anatomical definitions that describe white matter tracts. The definitions include adjacent gray and white matter regions, and rules for spatial relations. This novel method makes it possible to automatically label white matter anatomy across subjects. After describing this method, we provide an example of its implementation where we encode anatomical knowledge in human white matter for ten association and 15 projection tracts per hemisphere, along with seven commissural tracts. Importantly, this novel method is comparable in accuracy to manual labeling. Finally, we present results applying this method to create a white matter atlas from 77 healthy subjects, and we use this atlas in a small proof-of-concept study to detect changes in association tracts that characterize schizophrenia.

  9. Age, Cumulative Trauma and Stressful Life Events, and Post-Traumatic Stress Symptoms among Older Adults in Prison: Do Subjective Impressions Matter?

    Science.gov (United States)

    Maschi, Tina; Morgen, Keith; Zgoba, Kristen; Courtney, Deborah; Ristow, Jennifer

    2011-01-01

    Background: The aging prison population in the United States presents a significant public health challenge with high rates of trauma and mental health issues that the correctional system alone is ill-prepared to address. The purpose of this study was to examine the relationship of age, objective, and subjective measures of trauma and stressful…

  10. Using Academic Journals to Help Students Learn Subject Matter Content, Develop and Practice Critical Reasoning Skills, and Reflect on Personal Values in Food Science and Human Nutrition Classes

    Science.gov (United States)

    Iwaoka, Wayne T.; Crosetti, Lea M.

    2008-01-01

    It has been reported that students learn best when they use a wide variety of techniques to understand the information of the discipline, be it visual, auditory, discussion with others, metacognition, hands-on activities, or writing about the subject. We report in this article the use of academic journals not only as an aid for students to learn…

  11. A Structural Equation Model Analyzing the Relationship of Student Achievement Motivations and Personality Factors in a Range of Academic Subject-Matter Areas

    Science.gov (United States)

    Tempelaar, Dirk T.; Gijselaers, Wim H.; Schim van der Loeff, Sybrand; Nijhuis, Jan F. H.

    2007-01-01

    The question of subject-specificity of achievement motivations is important, both for educational psychology, as well as for educational policy. This study contributes to the investigation of the heterogeneity in achievement motivations in the context of the expectancy-value model. Whereas existing research deals with middle and high school…

  12. Evidence for Functional Networks within the Human Brain's White Matter.

    Science.gov (United States)

    Peer, Michael; Nitzan, Mor; Bick, Atira S; Levin, Netta; Arzy, Shahar

    2017-07-05

    Investigation of the functional macro-scale organization of the human cortex is fundamental in modern neuroscience. Although numerous studies have identified networks of interacting functional modules in the gray-matter, limited research was directed to the functional organization of the white-matter. Recent studies have demonstrated that the white-matter exhibits blood oxygen level-dependent signal fluctuations similar to those of the gray-matter. Here we used these signal fluctuations to investigate whether the white-matter is organized as functional networks by applying a clustering analysis on resting-state functional MRI (RSfMRI) data from white-matter voxels, in 176 subjects (of both sexes). This analysis indicated the existence of 12 symmetrical white-matter functional networks, corresponding to combinations of white-matter tracts identified by diffusion tensor imaging. Six of the networks included interhemispheric commissural bridges traversing the corpus callosum. Signals in white-matter networks correlated with signals from functional gray-matter networks, providing missing knowledge on how these distributed networks communicate across large distances. These findings were replicated in an independent subject group and were corroborated by seed-based analysis in small groups and individual subjects. The identified white-matter functional atlases and analysis codes are available at http://mind.huji.ac.il/white-matter.aspx Our results demonstrate that the white-matter manifests an intrinsic functional organization as interacting networks of functional modules, similarly to the gray-matter, which can be investigated using RSfMRI. The discovery of functional networks within the white-matter may open new avenues of research in cognitive neuroscience and clinical neuropsychiatry.SIGNIFICANCE STATEMENT In recent years, functional MRI (fMRI) has revolutionized all fields of neuroscience, enabling identifications of functional modules and networks in the human

  13. White matter organization in relation to upper limb motor control in healthy subjects: exploring the added value of diffusion kurtosis imaging.

    Science.gov (United States)

    Gooijers, J; Leemans, A; Van Cauter, S; Sunaert, S; Swinnen, S P; Caeyenberghs, K

    2014-09-01

    Diffusion tensor imaging (DTI) characterizes white matter (WM) microstructure. In many brain regions, however, the assumption that the diffusion probability distribution is Gaussian may be invalid, even at low b values. Recently, diffusion kurtosis imaging (DKI) was suggested to more accurately estimate this distribution. We explored the added value of DKI in studying the relation between WM microstructure and upper limb coordination in healthy controls (N = 24). Performance on a complex bimanual tracking task was studied with respect to the conventional DTI measures (DKI or DTI derived) and kurtosis metrics of WM tracts/regions carrying efferent (motor) output from the brain, corpus callosum (CC) substructures and whole brain WM. For both estimation models, motor performance was associated with fractional anisotropy (FA) of the CC-genu, CC-body, the anterior limb of the internal capsule, and whole brain WM (r s range 0.42-0.63). Although DKI revealed higher mean, radial and axial diffusivity and lower FA than DTI (p motor performance was associated with increased mean and radial kurtosis and kurtosis anisotropy (r s range 0.43-0.55). In conclusion, DKI provided additional information, but did not show increased sensitivity to detect relations between WM microstructure and bimanual performance in healthy controls.

  14. Dark matter an introduction

    CERN Document Server

    Majumdar, Debasish

    2015-01-01

    Dark Matter: An Introduction tackles the rather recent but fast-growing subject of astroparticle physics, encompassing three main areas of fundamental physics: cosmology, particle physics, and astrophysics. Accordingly, the book discusses symmetries, conservation laws, relativity, and cosmological parameters and measurements, as well as the astrophysical behaviors of galaxies and galaxy clusters that indicate the presence of dark matter and the possible nature of dark matter distribution.

  15. Do CS-US pairings actually matter? A within-subject comparison of instructed fear conditioning with and without actual CS-US pairings.

    Directory of Open Access Journals (Sweden)

    An K Raes

    Full Text Available Previous research showed that instructions about CS-US pairings can lead to fear of the CS even when the pairings are never presented. In the present study, we examined whether the experience of CS-US pairings adds to the effect of instructions by comparing instructed conditioning with and without actual CS-US pairings in a within-subject design. Thirty-two participants saw three fractals as CSs (CS(+1, CS(+2, CS(- and received electric shocks as USs. Before the start of a so-called training phase, participants were instructed that both CS(+1 and CS(+2 would be followed by the US, but only CS(+1 was actually paired with the US. The absence of the US after CS(+2 was explained in such a way that participants would not doubt the instructions about the CS(+2-US relation. After the training phase, a test phase was carried out. In this phase, participants expected the US after both CS(+s but none of the CS(+s was actually paired with the US. During test, self-reported fear was initially higher for CS(+1 than for CS(+2, which indicates that the experience of actual CS-US pairings adds to instructions about these pairings. On the other hand, the CS(+s elicited similar skin conductance responses and US expectancies. Theoretical and clinical implications are discussed.

  16. Increased white matter metabolic rates in autism spectrum disorder and schizophrenia.

    Science.gov (United States)

    Mitelman, Serge A; Buchsbaum, Monte S; Young, Derek S; Haznedar, M Mehmet; Hollander, Eric; Shihabuddin, Lina; Hazlett, Erin A; Bralet, Marie-Cecile

    2017-11-22

    Both autism spectrum disorder (ASD) and schizophrenia are often characterized as disorders of white matter integrity. Multimodal investigations have reported elevated metabolic rates, cerebral perfusion and basal activity in various white matter regions in schizophrenia, but none of these functions has previously been studied in ASD. We used 18fluorodeoxyglucose positron emission tomography to compare white matter metabolic rates in subjects with ASD (n = 25) to those with schizophrenia (n = 41) and healthy controls (n = 55) across a wide range of stereotaxically placed regions-of-interest. Both subjects with ASD and schizophrenia showed increased metabolic rates across the white matter regions assessed, including internal capsule, corpus callosum, and white matter in the frontal and temporal lobes. These increases were more pronounced, more widespread and more asymmetrical in subjects with ASD than in those with schizophrenia. The highest metabolic increases in both disorders were seen in the prefrontal white matter and anterior limb of the internal capsule. Compared to normal controls, differences in gray matter metabolism were less prominent and differences in adjacent white matter metabolism were more prominent in subjects with ASD than in those with schizophrenia. Autism spectrum disorder and schizophrenia are associated with heightened metabolic activity throughout the white matter. Unlike in the gray matter, the vector of white matter metabolic abnormalities appears to be similar in ASD and schizophrenia, may reflect inefficient functional connectivity with compensatory hypermetabolism, and may be a common feature of neurodevelopmental disorders.

  17. Front matter: Volume 10385

    Science.gov (United States)

    Assoufid, Lahsen; Ohashi, Haruhiko; Asundi, Anand K.

    2017-09-01

    This PDF file contains the front matter associated with SPIE Proceedings Volume 10385, including the Title Page, Copyright information, Table of Contents, Introduction, and Conference Committee listing.

  18. The effect of the 4MAT learning model on the achievement and motivation of 7th grade students on the subject of particulate nature of matter and an examination of student opinions on the model

    Science.gov (United States)

    Aktas, İdris; Bılgın, İbrahim

    2015-01-01

    Background:Many researchers agree that students, especially primary students, have learning difficulties on the 'Particulate Nature of Matter' unit. One reason for this difficulty is not considering individual differences for teaching science. In 4MAT model learning, environment is arranged according to individual differences. Purpose:The purpose of this study is to examine (1) the effects of the 4MAT learning model on the7th grade students' academic achievement and motivation on the 'Particulate Nature of Matter' unit and (2) identify student opinions on the 4MAT model. Sample:The sample consists of 235 students (115 experimental, 120 control) in Turkey. Design and methods:Experimental groups were instructed with the 4MAT model while control groups were instructed with a traditional method. Achievement Test (AchToM) and Motivation Scale (MotScl) were administered to students as pre- and post-tests. Moreover, the opinions of students in the experimental groups on the 4MAT model were ascertained through open-ended questions after the application. Results:According to independent t-test results, statistical difference in favour of the experimental groups was detected between the post-AchToM (ES = 1.43; p motivation and participation in the lesson, lessons are more amusing and enjoyable, and the self-confidence of the students increases. Besides these positive opinions, however, a few students stated that the method took too much time, they were not motivated and it did not help them in understanding the subject. Conclusions:The 4MAT model is more effective than traditional method in terms of increasing achievement and motivation. The model takes all learners into account. Thus, the teacher or educator should use the 4MAT model to ensure all students' learning in their classroom.

  19. Cosmetology. Subject Matters, Volume 3, No. 3.

    Science.gov (United States)

    Reese, Susan

    2001-01-01

    "The Beauty of Cosmetology" discusses the employment outlook for cosmetologists. "High School Cosmetology with Great Style" describes the academic and career cosmetology curriculum at Great Oaks Institute of Technology and Career Development (Ohio). "More than Skin Deep" explores the job shadowing program at the American Academy of Hair Design.…

  20. Digital Literacy and Subject Matter Learning

    DEFF Research Database (Denmark)

    Levinsen, Karin; Sørensen, Birgitte Holm

    2015-01-01

    It is generally agreed that learners need to acquire digital literacy in order to be able to act as citizens, employees and entrepreneurs in an increasingly digitalized environment. It is also generally agreed that the educational system has to be responsible for educating towards digital literacy....... However, there is no shared conception of the scope and meaning of digital literacy. The overall picture shows two main approaches: The first aims at digital literacy in the sense of Buildung (general education) while the second addresses a wide range of specific skills and competences: From basic...... computer skills over multimodal analysis to social conventions for behavior in online environments. Consequently designs for teaching and learning that aim at learners acquiring digital literacy and the related learning objectives appear as weak defined. According to the Danish Ministry of Education Shared...

  1. Language and Composition: Does the Subject Matter?

    Science.gov (United States)

    Alexis, Gerhard T.

    1968-01-01

    Attempts to combine language and composition in the freshman English course at Gustavus Adolphus College (St. Peter, Minnesota) should interest all teachers of English. One project utilized a single key word for several assignments. Students were asked to (1) think through the meaning of the word for a week and write definitions and associations,…

  2. Meeting the Challenge: Teaching Sensitive Subject Matter

    Science.gov (United States)

    Crosby, Dorian B.

    2012-01-01

    When teaching diversity courses that discuss sensitive issues, such as racial, gender, sexuality, religious, and ethnic discrimination, it is possible to encounter student resistance, which can subsequently prevent students from comprehending the content. While teaching an introductory course on African American history in a Black Studies…

  3. Active matter

    Science.gov (United States)

    Ramaswamy, Sriram

    2017-05-01

    The study of systems with sustained energy uptake and dissipation at the scale of the constituent particles is an area of central interest in nonequilibrium statistical physics. Identifying such systems as a distinct category—Active matter—unifies our understanding of autonomous collective movement in the living world and in some surprising inanimate imitations. In this article I present the active matter framework, briefly recall some early work, review our recent results on single-particle and collective behaviour, including experiments on active granular monolayers, and discuss new directions for the future.

  4. Language matters: an introduction.

    Science.gov (United States)

    Leap, William L; Provencher, Denis M

    2011-01-01

    That language and sexuality are closely connected is one of the enduring themes in human sexuality research. The articles in this special issue of the Journal of Homosexuality explore some of these language-centered insights as they apply to same-sex related desires, identities, and practices and to other dimensions of non-normative sexual experiences. The articles address language use over a range of geographic and social locations. The linguistic practices discussed are diverse, including the language associated with Santería, comments viewers make about gay pornography, homophobic discourse, coming out stories, stories where declarations of sexual identity are tacitly withheld, sexual messages in Black hip hop culture, assessments of urban AIDS ministries, and policies that limit transgender subjects' access to urban space. Taken together, these articles demonstrate that language matters in the everyday experience of sexual sameness and they model some of the approaches that are now being explored in language and sexuality studies.

  5. Speech Matters

    DEFF Research Database (Denmark)

    Hasse Jørgensen, Stina

    2011-01-01

    About Speech Matters - Katarina Gregos, the Greek curator's exhibition at the Danish Pavillion, the Venice Biannual 2011.......About Speech Matters - Katarina Gregos, the Greek curator's exhibition at the Danish Pavillion, the Venice Biannual 2011....

  6. Dark Matter

    Indian Academy of Sciences (India)

    matter and that it must be of some exotic type. Before we discuss the evidences for dark matter in clusters of galaxies, let us point out that it is not just spiral galaxies which are thought to contain dark matter, although the evidences from them are the strongest. Other types of galaxies, like elliptical galaxies, are often seen to ...

  7. White matter abnormalities of microstructure and physiological noise in schizophrenia.

    Science.gov (United States)

    Cheng, Hu; Newman, Sharlene D; Kent, Jerillyn S; Bolbecker, Amanda; Klaunig, Mallory J; O'Donnell, Brian F; Puce, Aina; Hetrick, William P

    2015-12-01

    White matter abnormalities in schizophrenia have been revealed by many imaging techniques and analysis methods. One of the findings by diffusion tensor imaging is a decrease in fractional anisotropy (FA), which is an indicator of white matter integrity. On the other hand, elevation of metabolic rate in white matter was observed from positron emission tomography (PET) studies. In this report, we aim to compare the two structural and functional effects on the same subjects. Our comparison is based on the hypothesis that signal fluctuation in white matter is associated with white matter functional activity. We examined the variance of the signal in resting state fMRI and found significant differences between individuals with schizophrenia and non-psychiatric controls specifically in white matter tissue. Controls showed higher temporal signal-to-noise ratios clustered in regions including temporal, frontal, and parietal lobes, cerebellum, corpus callosum, superior longitudinal fasciculus, and other major white matter tracts. These regions with higher temporal signal-to-noise ratio agree well with those showing higher metabolic activity reported by studies using PET. The results suggest that individuals with schizophrenia tend to have higher functional activity in white matter in certain brain regions relative to healthy controls. Despite some overlaps, the distinct regions for physiological noise are different from those for FA derived from diffusion tensor imaging, and therefore provide a unique angle to explore potential mechanisms to white matter abnormality.

  8. The Subjectivity of Participation

    DEFF Research Database (Denmark)

    Nissen, Morten

    What is a 'we' – a collective – and how can we use such communal self-knowledge to help people? This book is about collectivity, participation, and subjectivity – and about the social theories that may help us understand these matters. It also seeks to learn from the innovative practices and ideas...... practices. Through this dialogue, it develops an original trans-disciplinary critical theory and practice of collective subjectivity for which the ongoing construction and overcoming of common sense, or ideology, is central. It also points to ways of relating discourse with agency, and fertilizing insights...... from interactionism and ideology theories in a cultural-historical framework....

  9. A voxel-based morphometric magnetic resonance imaging study of the brain detects age-related gray matter volume changes in healthy subjects of 21–45 years old

    Science.gov (United States)

    El-Beltagi, Ahmed; Cherian, Jigi; Gejo, Grace; Al-Jazzaf, Abrar; Ismail, Mohammad

    2015-01-01

    Previous and more recent work of analyzing structural changes in the brain suggest that certain brain regions such as the frontal lobe are among the brain regions profoundly affected by the aging process across males and females. Also, a unified model of structural changes in a normally aging brain is still lacking. The present study investigated age-related structural brain changes in gray matter from young to early middle-age adulthood for males and females. Magnetic resonance images of 215 normal and healthy participants between the ages of 21–45 years were acquired. Changes in gray matter were assessed using voxel-based morphometry and gray matter volumetric analysis. The results showed significant decrease in gray matter volume between the youngest and oldest groups in the following brain regions: frontal, temporal, and parietal lobes. Grey matter loss in the frontal lobe was among the most widespread of all brain regions across the comparison groups that showed significant age-related changes in grey matter for both males and females. This work provides a unique pattern of age-related decline of normal and healthy adult males and females that can aid in the future development of a unified model of normal brain aging. PMID:26306927

  10. A voxel-based morphometric magnetic resonance imaging study of the brain detects age-related gray matter volume changes in healthy subjects of 21-45 years old.

    Science.gov (United States)

    Bourisly, Ali K; El-Beltagi, Ahmed; Cherian, Jigi; Gejo, Grace; Al-Jazzaf, Abrar; Ismail, Mohammad

    2015-10-01

    Previous and more recent work of analyzing structural changes in the brain suggest that certain brain regions such as the frontal lobe are among the brain regions profoundly affected by the aging process across males and females. Also, a unified model of structural changes in a normally aging brain is still lacking. The present study investigated age-related structural brain changes in gray matter from young to early middle-age adulthood for males and females. Magnetic resonance images of 215 normal and healthy participants between the ages of 21-45 years were acquired. Changes in gray matter were assessed using voxel-based morphometry and gray matter volumetric analysis. The results showed significant decrease in gray matter volume between the youngest and oldest groups in the following brain regions: frontal, temporal, and parietal lobes. Grey matter loss in the frontal lobe was among the most widespread of all brain regions across the comparison groups that showed significant age-related changes in grey matter for both males and females. This work provides a unique pattern of age-related decline of normal and healthy adult males and females that can aid in the future development of a unified model of normal brain aging. © The Author(s) 2015.

  11. Macro Dark Matter

    CERN Document Server

    Jacobs, David M; Lynn, Bryan W.

    2015-01-01

    Dark matter is a vital component of the current best model of our universe, $\\Lambda$CDM. There are leading candidates for what the dark matter could be (e.g. weakly-interacting massive particles, or axions), but no compelling observational or experimental evidence exists to support these particular candidates, nor any beyond-the-Standard-Model physics that might produce such candidates. This suggests that other dark matter candidates, including ones that might arise in the Standard Model, should receive increased attention. Here we consider a general class of dark matter candidates with characteristic masses and interaction cross-sections characterized in units of grams and cm$^2$, respectively -- we therefore dub these macroscopic objects as Macros. Such dark matter candidates could potentially be assembled out of Standard Model particles (quarks and leptons) in the early universe. A combination of earth-based, astrophysical, and cosmological observations constrain a portion of the Macro parameter space; ho...

  12. Expanding subjectivities

    DEFF Research Database (Denmark)

    Lundgaard Andersen, Linda; Soldz, Stephen

    2012-01-01

    A major theme in recent psychoanalytic thinking concerns the use of therapist subjectivity, especially “countertransference,” in understanding patients. This thinking converges with and expands developments in qualitative research regarding the use of researcher subjectivity as a tool to understa...

  13. Dark Matter

    Indian Academy of Sciences (India)

    In Part 11 of this article we learnt that there are compelling evidences from dynamics of spiral galaxies, like our own, that there must be non-luminous matter in them. In this second part we will see that even clusters of galaxies must harbour dark matter. As if this was not enough, it turns out that if our knowledge of the ...

  14. Describing Matter

    Science.gov (United States)

    Adams, Krista; Feagin, Shannon

    2017-01-01

    This article presents a lesson that was designed to explore the scientific descriptions of matter through both the intensive and extensive properties that students successfully added to their vocabulary. Students' examples demonstrated that there were places where their reasoning about matter faltered as related to how the material is the same…

  15. The brain subcortical white matter and aging: A quantitative fractional anisotropy analysis

    Directory of Open Access Journals (Sweden)

    Eliasz Engelhardt

    Full Text Available Abstract To study the integrity of hemispheric subcortical white matter by comparing normal young and elderly subjects using quantitative fractional anisotropy (DTI-FA. Methods: Subjects of two different age groups (young=12, elderly=12 were included. MR - GE Signa Horizon - 1.5T scans were performed. Cases with Fazekas scores £3 were assessed on FLAIR sequence. Standard parameters for DTI-FA were used. ROIs were placed at various sites of the subcortical white matter, and the genu and splenium of the midline corpus callosum. Analysis was performed using Functool. Statistics for anterior and posterior white matter, as well as the genu and splenium were compared between the groups. The study was approved by the Ethics Committee of IPUB-UFRJ and informed consent obtained. Results: DTI-FA showed lower anisotropy values in the anterior region (subcortical white matter and genu, but not in the posterior region (subcortical white matter and splenium, in elderly normal subjects compared to young subjects. Conclusion: The results may represent loss of integrity of anterior (frontal white matter fibers in the elderly subjects. These fibers constitute important intra- and inter-hemispheric tracts, components of neural networks that provide cognitive, behavioral, motor and sensory integration. The loss of integrity of the anterior segments of the studied fiber systems with ageing, represents a disconnection process that may underlie clinical manifestations found in elderly subjects such as executive dysfunction.

  16. Physics of condensed matter

    CERN Document Server

    Misra, Prasanta K

    2012-01-01

    Physics of Condensed Matter is designed for a two-semester graduate course on condensed matter physics for students in physics and materials science. While the book offers fundamental ideas and topic areas of condensed matter physics, it also includes many recent topics of interest on which graduate students may choose to do further research. The text can also be used as a one-semester course for advanced undergraduate majors in physics, materials science, solid state chemistry, and electrical engineering, because it offers a breadth of topics applicable to these majors. The book be

  17. Subject (of documents)

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2017-01-01

    such as concepts, aboutness, topic, isness and ofness are also briefly presented. The conclusion is that the most fruitful way of defining “subject” (of a document) is the documents informative or epistemological potentials, that is, the documents potentials of informing users and advance the development......This article presents and discuss the concept “subject” or subject matter (of documents) as it has been examined in library and information science (LIS) for more than 100 years. Different theoretical positions are outlined and it is found that the most important distinction is between document......-oriented views versus request-oriented views. The document-oriented view conceive subject as something inherent in documents, whereas the request-oriented view (or the policy based view) understand subject as an attribution made to documents in order to facilitate certain uses of them. Related concepts...

  18. Dark matter universe.

    Science.gov (United States)

    Bahcall, Neta A

    2015-10-06

    Most of the mass in the universe is in the form of dark matter--a new type of nonbaryonic particle not yet detected in the laboratory or in other detection experiments. The evidence for the existence of dark matter through its gravitational impact is clear in astronomical observations--from the early observations of the large motions of galaxies in clusters and the motions of stars and gas in galaxies, to observations of the large-scale structure in the universe, gravitational lensing, and the cosmic microwave background. The extensive data consistently show the dominance of dark matter and quantify its amount and distribution, assuming general relativity is valid. The data inform us that the dark matter is nonbaryonic, is "cold" (i.e., moves nonrelativistically in the early universe), and interacts only weakly with matter other than by gravity. The current Lambda cold dark matter cosmology--a simple (but strange) flat cold dark matter model dominated by a cosmological constant Lambda, with only six basic parameters (including the density of matter and of baryons, the initial mass fluctuations amplitude and its scale dependence, and the age of the universe and of the first stars)--fits remarkably well all the accumulated data. However, what is the dark matter? This is one of the most fundamental open questions in cosmology and particle physics. Its existence requires an extension of our current understanding of particle physics or otherwise point to a modification of gravity on cosmological scales. The exploration and ultimate detection of dark matter are led by experiments for direct and indirect detection of this yet mysterious particle.

  19. Dynamics of Soft Matter

    CERN Document Server

    García Sakai, Victoria; Chen, Sow-Hsin

    2012-01-01

    Dynamics of Soft Matter: Neutron Applications provides an overview of neutron scattering techniques that measure temporal and spatial correlations simultaneously, at the microscopic and/or mesoscopic scale. These techniques offer answers to new questions arising at the interface of physics, chemistry, and biology. Knowledge of the dynamics at these levels is crucial to understanding the soft matter field, which includes colloids, polymers, membranes, biological macromolecules, foams, emulsions towards biological & biomimetic systems, and phenomena involving wetting, friction, adhesion, or micr

  20. The Relationship between Dry Matter Increase of Seed and Shoot during the Seed-Filling Period in Three Kinds of Soybeans with Different Growth Habits Subjected to Shading and Thinning

    National Research Council Canada - National Science Library

    Kakiuchi, Jin; Kobata, Tohru

    2006-01-01

    The ratio of dry-matter increase in seed (S) to that in shoot (W), referred to as RS/W, during the seed-filling period may reflect the balance between the assimilate supply and the sink capacity of harvest organs...

  1. Antimatter Matters

    CERN Multimedia

    CERN

    2016-01-01

    This video is a teaser-introduction to the Antimatter Matters exhibtion at the Royal Society's Summer Science exhibition July 4-10 2016. The exhibition is jointly organised and hosted by UK members of the ALPHA and LHCb collaborations.

  2. Dark matter universe

    Science.gov (United States)

    Bahcall, Neta A.

    2015-01-01

    Most of the mass in the universe is in the form of dark matter—a new type of nonbaryonic particle not yet detected in the laboratory or in other detection experiments. The evidence for the existence of dark matter through its gravitational impact is clear in astronomical observations—from the early observations of the large motions of galaxies in clusters and the motions of stars and gas in galaxies, to observations of the large-scale structure in the universe, gravitational lensing, and the cosmic microwave background. The extensive data consistently show the dominance of dark matter and quantify its amount and distribution, assuming general relativity is valid. The data inform us that the dark matter is nonbaryonic, is “cold” (i.e., moves nonrelativistically in the early universe), and interacts only weakly with matter other than by gravity. The current Lambda cold dark matter cosmology—a simple (but strange) flat cold dark matter model dominated by a cosmological constant Lambda, with only six basic parameters (including the density of matter and of baryons, the initial mass fluctuations amplitude and its scale dependence, and the age of the universe and of the first stars)—fits remarkably well all the accumulated data. However, what is the dark matter? This is one of the most fundamental open questions in cosmology and particle physics. Its existence requires an extension of our current understanding of particle physics or otherwise point to a modification of gravity on cosmological scales. The exploration and ultimate detection of dark matter are led by experiments for direct and indirect detection of this yet mysterious particle. PMID:26417091

  3. Inflatable Dark Matter.

    Science.gov (United States)

    Davoudiasl, Hooman; Hooper, Dan; McDermott, Samuel D

    2016-01-22

    We describe a general scenario, dubbed "inflatable dark matter," in which the density of dark matter particles can be reduced through a short period of late-time inflation in the early Universe. The overproduction of dark matter that is predicted within many, otherwise, well-motivated models of new physics can be elegantly remedied within this context. Thermal relics that would, otherwise, be disfavored can easily be accommodated within this class of scenarios, including dark matter candidates that are very heavy or very light. Furthermore, the nonthermal abundance of grand unified theory or Planck scale axions can be brought to acceptable levels without invoking anthropic tuning of initial conditions. A period of late-time inflation could have occurred over a wide range of scales from ∼MeV to the weak scale or above, and could have been triggered by physics within a hidden sector, with small but not necessarily negligible couplings to the standard model.

  4. Neutrino Propagation in Matter

    Directory of Open Access Journals (Sweden)

    Mattias Blennow

    2013-01-01

    Full Text Available We describe the effects of neutrino propagation in the matter of the Earth relevant to experiments with atmospheric and accelerator neutrinos and aimed at the determination of the neutrino mass hierarchy and CP violation. These include (i the resonance enhancement of neutrino oscillations in matter with constant or nearly constant density, (ii adiabatic conversion in matter with slowly changing density, (iii parametric enhancement of oscillations in a multilayer medium, and (iv oscillations in thin layers of matter. We present the results of semianalytic descriptions of flavor transitions for the cases of small density perturbations, in the limit of large densities and for small density widths. Neutrino oscillograms of the Earth and their structure after determination of the 1–3 mixing are described. A possibility to identify the neutrino mass hierarchy with the atmospheric neutrinos and multimegaton scale detectors having low energy thresholds is explored. The potential of future accelerator experiments to establish the hierarchy is outlined.

  5. 34 CFR 303.15 - Include; including.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Include; including. 303.15 Section 303.15 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EARLY INTERVENTION PROGRAM FOR INFANTS AND TODDLERS WITH...

  6. SUBJECT INDEX

    Indian Academy of Sciences (India)

    Subject Index. Variation of surface electric field during geomagnetic disturbed period at Maitri, Antarctica. 1721. Geomorphology. A simple depression-filling method for raster and irregular elevation datasets. 1653. Decision Support System integrated with Geographic. Information System to target restoration actions in water-.

  7. A voxel-based morphometric magnetic resonance imaging study of the brain detects age-related gray matter volume changes in healthy subjects of 21–45 years old

    OpenAIRE

    Bourisly, Ali K; El-Beltagi, Ahmed; Cherian, Jigi; Gejo, Grace; Al-Jazzaf, Abrar; Ismail, Mohammad

    2015-01-01

    Previous and more recent work of analyzing structural changes in the brain suggest that certain brain regions such as the frontal lobe are among the brain regions profoundly affected by the aging process across males and females. Also, a unified model of structural changes in a normally aging brain is still lacking. The present study investigated age-related structural brain changes in gray matter from young to early middle-age adulthood for males and females. Magnetic resonance images of 215...

  8. Sirius Matters

    CERN Document Server

    Brosch, Noah

    2008-01-01

    Since very early times Sirius was a point of attraction in the night sky. It served to synchronize calendars in antiquity and was the subject of many myths and legends, including some modern ones. It was perceived as a red star for more than 400 years, but such reports were relegated to the Mediterranean region. Astronomically, Sirius is a very bright star. This, and its present close distance to us, argues in favor of it being the target of detailed studies of stellar structure and evolution. Its binary nature, with a companion that is one of the more massive white dwarfs, is an additional reason for such studies. This book collects the published information on Sirius in an attempt to derive a coherent picture of how this system came to look as it does.

  9. Children's Differentiation between Beliefs about Matters of Fact and Matters of Opinion

    Science.gov (United States)

    Banerjee, Robin; Yuill, Nicola; Larson, Christina; Easton, Kate; Robinson, Elizabeth; Rowley, Martin

    2007-01-01

    Two experiments investigated children's implicit and explicit differentiation between beliefs about matters of fact and matters of opinion. In Experiment 1, 8- to 9-year-olds' (n = 88) explicit understanding of the subjectivity of opinions was found to be limited, but their conformity to others' judgments on a matter of opinion was considerably…

  10. Cold Quark Matter

    CERN Document Server

    Kurkela, Aleksi; Vuorinen, Aleksi

    2010-01-01

    We perform an O(alpha_s^2) perturbative calculation of the equation of state of cold but dense QCD matter with two massless and one massive quark flavor, finding that perturbation theory converges reasonably well for quark chemical potentials above 1 GeV. Using a running coupling constant and strange quark mass, and allowing for further non-perturbative effects, our results point to a narrow range where absolutely stable strange quark matter may exist. Absent stable strange quark matter, our findings suggest that quark matter in compact star cores becomes confined to hadrons only slightly above the density of atomic nuclei. Finally, we show that equations of state including quark matter lead to hybrid star masses up to M~2M_solar, in agreement with current observations. For strange stars, we find maximal masses of M~2.75M_solar and conclude that confirmed observations of compact stars with M>2M_solar would strongly favor the existence of stable strange quark matter.

  11. Interchange Instability and Transport in Matter-Antimatter Plasmas.

    Science.gov (United States)

    Kendl, Alexander; Danler, Gregor; Wiesenberger, Matthias; Held, Markus

    2017-06-09

    Symmetric electron-positron plasmas in inhomogeneous magnetic fields are intrinsically subject to interchange instability and transport. Scaling relations for the propagation velocity of density perturbations relevant to transport in isothermal magnetically confined electron-positron plasmas are deduced, including damping effects when Debye lengths are large compared to Larmor radii. The relations are verified by nonlinear full-F gyrofluid computations. Results are analyzed with respect to planned magnetically confined electron-positron plasma experiments. The model is generalized to other matter-antimatter plasmas. Magnetized electron-positron-proton-antiproton plasmas are susceptible to interchange-driven local matter-antimatter separation, which can impede sustained laboratory magnetic confinement.

  12. Bootstrapping white matter segmentation, Eve++

    Science.gov (United States)

    Plassard, Andrew; Hinton, Kendra E.; Venkatraman, Vijay; Gonzalez, Christopher; Resnick, Susan M.; Landman, Bennett A.

    2015-03-01

    Multi-atlas labeling has come in wide spread use for whole brain labeling on magnetic resonance imaging. Recent challenges have shown that leading techniques are near (or at) human expert reproducibility for cortical gray matter labels. However, these approaches tend to treat white matter as essentially homogeneous (as white matter exhibits isointense signal on structural MRI). The state-of-the-art for white matter atlas is the single-subject Johns Hopkins Eve atlas. Numerous approaches have attempted to use tractography and/or orientation information to identify homologous white matter structures across subjects. Despite success with large tracts, these approaches have been plagued by difficulties in with subtle differences in course, low signal to noise, and complex structural relationships for smaller tracts. Here, we investigate use of atlas-based labeling to propagate the Eve atlas to unlabeled datasets. We evaluate single atlas labeling and multi-atlas labeling using synthetic atlases derived from the single manually labeled atlas. On 5 representative tracts for 10 subjects, we demonstrate that (1) single atlas labeling generally provides segmentations within 2mm mean surface distance, (2) morphologically constraining DTI labels within structural MRI white matter reduces variability, and (3) multi-atlas labeling did not improve accuracy. These efforts present a preliminary indication that single atlas labels with correction is reasonable, but caution should be applied. To purse multi-atlas labeling and more fully characterize overall performance, more labeled datasets would be necessary.

  13. Matter and memory

    CERN Document Server

    Bergson, Henri

    1991-01-01

    Since the end of the last century," Walter Benjamin wrote, "philosophy has made a series of attempts to lay hold of the 'true' experience as opposed to the kind that manifests itself in the standardized, denatured life of the civilized masses. It is customary to classify these efforts under the heading of a philosophy of life. Towering above this literature is Henri Bergson's early monumental work, Matter and Memory."Along with Husserl's Ideas and Heidegger's Being and Time, Bergson's work represents one of the great twentieth-century investigations into perception and memory, movement and time, matter and mind. Arguably Bergson's most significant book, Matter and Memory is essential to an understanding of his philosophy and its legacy.This new edition includes an annotated bibliography prepared by Bruno Paradis.Henri Bergson (1859-1941) was awarded the Nobel Prize in 1927. His works include Time and Free Will, An Introduction to Metaphysics, Creative Evolution, and The Creative Mind.

  14. Dark Matter

    Indian Academy of Sciences (India)

    The study of gas clouds orbiting in the outer regions of spiral galaxies has revealed that their gravitational at- traction is much larger than the stars alone can provide. Over the last twenty years, astronomers have been forced to postulate the presence of large quantities of 'dark matter' to explain their observations. They are ...

  15. Molecule Matters

    Indian Academy of Sciences (India)

    Fluorescence usually originates from the lowest excited electronic state (singlet) irrespective of the excitation and hence, the fluorescence spectrum of a molecule is characterized by a single band. However, what makes DMABN a very special molecule is that it exhibits dual fluorescence (i.e. emission of. Molecule Matters.

  16. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 14; Issue 4. Molecule Matters – van der Waals Molecules - History and Some Perspectives on Intermolecular Forces. E Arunan. Feature Article Volume 14 Issue 4 April 2009 pp 346-356 ...

  17. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 9. Molecule Matters - A Chromium Compound with a Quintuple Bond. K C Kumara Swamy. Feature Article Volume 11 Issue 9 September 2006 pp 72-75. Fulltext. Click here to view fulltext PDF. Permanent link:

  18. Science Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 2. Science Matters A Book for Curious Minds. Rohini Godbole. Book Review Volume 2 Issue 2 February 1997 pp 94-95. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/002/02/0094-0095 ...

  19. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 5. Molecule Matters - N-Heterocyclic Carbenes - The Stable Form of R2 C: Anil J Elias. Feature Article Volume 13 Issue 5 May 2008 pp 456-467. Fulltext. Click here to view fulltext PDF. Permanent link:

  20. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 11. Molecule Matters - Carbon Dioxide: Molecular States and Beyond. T P Radhakrishnan. Feature Article Volume 11 Issue 11 November 2006 pp 88-92. Fulltext. Click here to view fulltext PDF. Permanent link:

  1. Condensed Matter Field Theory

    Science.gov (United States)

    Altland, Alexander; Simons, Ben

    2006-06-01

    Over the past few decades, in concert with ground-breaking experimental advances, condensed matter theory has drawn increasingly from the language of low-energy quantum field theory. This primer is aimed at elevating graduate students of condensed matter theory to a level where they can engage in independent research. It emphasizes the development of modern methods of classical and quantum field theory with applications oriented around condensed matter physics. Topics covered include second quantization, path and functional field integration, mean-field theory and collective phenomena, the renormalization group, and topology. Conceptual aspects and formal methodology are emphasized, but the discussion is rooted firmly in practical experimental application. As well as routine exercises, the text includes extended and challenging problems, with fully worked solutions, designed to provide a bridge between formal manipulations and research-oriented thinking. This book will complement graduate level courses on theoretical quantum condensed matter physics. Spans the field of modern condensed matter theory focusing on field theory techniques Written to facilitate learning, with numerous challenging exercises, with fully worked solutions, aimed at physicists starting graduate-level courses The theoretical methods are firmly set in concrete experimental applications

  2. Resident Assistant Mattering: Do Placement and Community Size Matter?

    Science.gov (United States)

    Stoner, James C.; Zhang, Yi

    2017-01-01

    A sense of mattering among college students has been found to have positive outcomes, including lower levels of anxiety and depression as well as increased self-esteem, wellness, happiness, and job satisfaction. However, the feeling of mattering among Resident Assistants (RAs) has received little attention in literature. This quantitative study…

  3. Superficial white matter damage in anti-NMDA receptor encephalitis.

    Science.gov (United States)

    Phillips, Owen Robert; Joshi, Shantanu H; Narr, Katherine L; Shattuck, David W; Singh, Manpreet; Di Paola, Margherita; Ploner, Christoph J; Prüss, Harald; Paul, Friedemann; Finke, Carsten

    2017-11-03

    Clinical brain MRI is normal in the majority of patients with anti- N -methyl-D-aspartate receptor (NMDAR) encephalitis. However, extensive deep white matter damage wasrecently identifiedin these patients using diffusion weighted imaging. Here, our aim was to study a particularly vulnerable brain compartment, the late myelinating superficial white matter. Forty-six patients with anti-NMDAR encephalitis were included. Ten out of these were considered neurologically recovered (modified Rankin scale of zero), while 36 patients were non-recovered. In addition, 30 healthy controls were studied. MRI data were collected from all subjects and superficial white matter mean diffusivity derived from diffusion tensor imaging was compared between groups in whole brain, lobar and vertex-based analyses. Patients underwent comprehensive cognitive testing, and correlation analyses were performed between cognitive performance and superficial white matter integrity. Non-recovered patients showed widespread superficial white matter damage in comparison to recovered patients and healthy controls. Vertex-based analyses revealed that damage predominated in frontal and temporal lobes. In contrast, the superficial white matter was intact in recovered patients. Importantly, persistent cognitive impairments in working memory, verbal memory, visuospatial memory and attention significantly correlated with damage of the superficial white matter in patients. Anti-NMDAR encephalitis is associated with extensive superficial white matter damage in patients with incomplete recovery. The strong association with impairment in several cognitive domains highlights the clinical relevance of white matter damage in this disorder and warrants investigations of the underlying pathophysiological mechanisms. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  4. Altered White Matter Integrity in the Congenital and Late Blind People

    Directory of Open Access Journals (Sweden)

    Dawei Wang

    2013-01-01

    Full Text Available The blind subjects have experienced a series of brain structural and functional alterations due to the visual deprivation. It remains unclear as to whether white matter changes differ between blind subjects with visual deprivation before and after a critical developmental period. The present study offered a direct comparison in changes of white matter fractional anisotropy (FA between congenital blind (CB and late blind (LB individuals. Twenty CB, 21 LB (blindness onset after 18 years old, and 40 sight control (SC subjects were recruited. Both the tract-based spatial statistics (TBSS and voxel-based analysis (VBA showed lower FA in the bilateral optic radiations in both blind groups, suggesting that the loss of white matter integrity was the prominent hallmark in the blind people. The LB group showed more extensive white matter impairment than the CB group, indicating the mechanisms of white matter FA changes are different between the CB and LB groups. Using a loose threshold, a trend of an increased FA was found in the bilateral corticospinal tracts in the LB but with a smaller spatial extent relative to the CB. These results suggest that white matter FA changes in the blind subjects are the reflection of multiple mechanisms, including the axonal degeneration, deafferentation, and plasticity.

  5. An elusive vector dark matter

    Directory of Open Access Journals (Sweden)

    Chuan-Ren Chen

    2015-02-01

    Full Text Available Even though the sensitivity of direct dark matter search experiments reaches the level of about 10−45 cm2, no confident signal of dark matter has been observed. We point out that, if dark matter is a vector boson, the null result in direct dark matter search experiments may be due to the destructive effects in dark-matter–nucleon elastic scattering. We illustrate the scenario using a modified Higgs portal model that includes exotic quarks. The significant cancellation can occur for a certain mass gap between new heavy quark and dark matter. As a result, the spin-independent dark-matter–nucleon elastic scattering is so suppressed that the future direct search experiments will hardly observe the signal of dark matter.

  6. Education Matters, January 2008

    Science.gov (United States)

    Beckner, Gary, Ed.

    2008-01-01

    "Education Matters" is the monthly newsletter of the Association of American Educators (AAE), an organization dedicated to advancing the American teaching profession through personal growth, professional development, teacher advocacy and protection. This issue of the newsletter includes: (1) Agents of Change: Why So Many Teachers Are…

  7. Education Matters, May 2011

    Science.gov (United States)

    Beckner, Gary, Ed.

    2011-01-01

    "Education Matters" is the monthly newsletter of the Association of American Educators (AAE), an organization dedicated to advancing the American teaching profession through personal growth, professional development, teacher advocacy and protection. This issue of the newsletter includes: (1) Balancing Act: Achieving a Harmony between…

  8. Education Matters, May 2010

    Science.gov (United States)

    Beckner, Gary, Ed.

    2010-01-01

    "Education Matters" is the monthly newsletter of the Association of American Educators (AAE), an organization dedicated to advancing the American teaching profession through personal growth, professional development, teacher advocacy and protection. This issue of the newsletter includes: (1) Who Me? Yes, You Can Use Technology to Individualize…

  9. Education Matters, May 2008

    Science.gov (United States)

    Beckner, Gary, Ed.

    2008-01-01

    "Education Matters" is the monthly newsletter of the Association of American Educators (AAE), an organization dedicated to advancing the American teaching profession through personal growth, professional development, teacher advocacy and protection. This issue of the newsletter includes: (1) Is She Your Competition? Are India's Students…

  10. Education Matters, April 2010

    Science.gov (United States)

    Beckner, Gary, Ed.

    2010-01-01

    "Education Matters" is the monthly newsletter of the Association of American Educators (AAE), an organization dedicated to advancing the American teaching profession through personal growth, professional development, teacher advocacy and protection. This issue of the newsletter includes: (1) Teaching as Leadership: 6 Traits of Highly…

  11. Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy

    Energy Technology Data Exchange (ETDEWEB)

    Yu Aihong [Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053 (China); Li Kuncheng [Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053 (China)], E-mail: Likuncheng@vip.sina.com; Li Lin; Shan Baoci [Institute of High Energy Physics, Chinese Academy of Sciences (China); Wang Yuping; Xue Sufang [Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences (China)

    2008-01-15

    Purpose: The purpose of this study was to analyze whole-brain white matter changes in medial temporal lobe epilepsy (MTLE). Materials and methods: We studied 23 patients with MTLE and 13 age- and sex-matched healthy control subjects using voxel-based morphometry (VBM) on T1-weighted 3D datasets. The seizure focus was right sided in 11 patients and left sided in 12. The data were collected on a 1.5 T MR system and analyzed by SPM 99 to generate white matter density maps. Results: Voxel-based morphometry revealed diffusively reduced white matter in MTLE prominently including bilateral frontal lobes, bilateral temporal lobes and corpus callosum. White matter reduction was also found in the bilateral cerebellar hemispheres in the left MTLE group. Conclusion: VBM is a simple and automated approach that is able to identify diffuse whole-brain white matter reduction in MTLE.

  12. Correlating Cognitive Decline with White Matter Lesion and Brain Atrophy Magnetic Resonance Imaging Measurements in Alzheimer's Disease.

    Science.gov (United States)

    Bilello, Michel; Doshi, Jimit; Nabavizadeh, S Ali; Toledo, Jon B; Erus, Guray; Xie, Sharon X; Trojanowski, John Q; Han, Xiaoyan; Davatzikos, Christos

    2015-01-01

    Vascular risk factors are increasingly recognized as risks factors for Alzheimer's disease (AD) and early conversion from mild cognitive impairment (MCI) to dementia. While neuroimaging research in AD has focused on brain atrophy, metabolic function, or amyloid deposition, little attention has been paid to the effect of cerebrovascular disease to cognitive decline. To investigate the correlation of brain atrophy and white matter lesions with cognitive decline in AD, MCI, and control subjects. Patients with AD and MCI, and healthy subjects were included in this study. Subjects had a baseline MRI scan, and baseline and follow-up neuropsychological battery (CERAD). Regional volumes were measured, and white matter lesion segmentation was performed. Correlations between rate of CERAD score decline and white matter lesion load and brain structure volume were evaluated. In addition, voxel-based correlations between baseline CERAD scores and atrophy and white matter lesion measures were computed. CERAD rate of decline was most significantly associated with lesion loads located in the fornices. Several temporal lobe ROI volumes were significantly associated with CERAD decline. Voxel-based analysis demonstrated strong correlation between baseline CERAD scores and atrophy measures in the anterior temporal lobes. Correlation of baseline CERAD scores with white matter lesion volumes achieved significance in multilobar subcortical white matter. Both baseline and declines in CERAD scores correlate with white matter lesion load and gray matter atrophy. Results of this study highlight the dominant effect of volume loss, and underscore the importance of small vessel disease as a contributor to cognitive decline in the elderly.

  13. Voxelwise meta-analysis of gray matter abnormalities in bipolar disorder.

    Science.gov (United States)

    Bora, Emre; Fornito, Alex; Yücel, Murat; Pantelis, Christos

    2010-06-01

    We conducted a meta-analysis of gray matter abnormalities in bipolar disorder (BD) using voxel-based morphometry studies to help clarify the structural abnormalities underpinning this condition. A systematic review was conducted for voxel-based morphometry studies of patients with BD. Meta-analyses of gray matter differences between BD and control subjects were undertaken using "signed differential mapping," a novel method that, in contrast to previously used techniques, allows inclusion of negative findings and ensures that single studies do not exert undue influence on the results. Meta-regression and subgroup analyses were used to examine the effect of moderator variables on gray matter abnormalities. A total of 21 studies comparing gray matter volumes of 660 BD patients and 770 healthy control subjects were included. Gray matter reduction in left rostral anterior cingulate cortex (ACC) and right fronto-insular cortex was associated with BD. Fronto-insular cortex abnormality was not evident in early phases of the illness. In chronic patients, longer duration of illness was associated with increased gray matter in a cluster that included basal ganglia, subgenual ACC, and amygdala. Lithium treatment was associated with enlargement of ACC gray matter volumes, which overlapped with the region where gray matter was reduced in BD. The most robust gray matter reductions in BD occur in anterior limbic regions, which may be related to the executive control and emotional processing abnormalities seen in this patient population. Clinical factors such as illness duration and lithium treatment also impact on case-control comparisons of gray matter volume. Copyright 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  14. Extent of altered white matter in unilateral and bilateral periventricular white matter lesions in children with unilateral cerebral palsy.

    Science.gov (United States)

    Scheck, Simon M; Fripp, Jurgen; Reid, Lee; Pannek, Kerstin; Fiori, Simona; Boyd, Roslyn N; Rose, Stephen E

    2016-08-01

    To investigate the extent of white matter damage in children with unilateral cerebral palsy (UCP) caused by periventricular white matter lesions comparing between unilateral and bilateral lesions; and to investigate a relationship between white matter microstructure and hand function. Diffusion MRI images from 46 children with UCP and 18 children with typical development (CTD) were included. Subjects were grouped by side of hemiparesis and unilateral or bilateral lesions. A voxel-wise white matter analysis was performed to identify regions where fractional anisotropy (FA) was significantly different between UCP groups and CTD; and where FA correlated with either dominant or impaired hand function (using Jebsen Taylor Hand Function Test). Children with unilateral lesions had reduced FA in the corticospinal tract of the affected hemisphere. Children with bilateral lesions had widespread reduced FA extending into all lobes. In children with left hemiparesis, impaired hand function correlated with FA in the contralateral corticospinal tract. Dominant hand function correlated with FA in the posterior thalamic radiations as well as multiple other regions in both left and right hemiparesis groups. Periventricular white matter lesions consist of focal and diffuse components. Focal lesions may cause direct motor fibre insult resulting in motor impairment. Diffuse white matter injury is heterogeneous, and may contribute to more global dysfunction. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Exploring the mirror matter interpretation of the DAMA experiment: Has the dark matter problem been solved?

    OpenAIRE

    Foot, R.

    2004-01-01

    The self consistency between the impressive DAMA annual modulation signal and the differential energy spectrum is an important test for dark matter candidates.Mirror matter-type dark matter passes this test while other dark matter candidates, including standard (spin-independent) WIMPs and mini-electric charged particle dark matter, do not do so well.We argue that the unique properties of mirror matter-type dark matter seem to be just those required to fully explain the data, suggesting that ...

  16. Gray matter and white matter abnormalities in online game addiction

    Energy Technology Data Exchange (ETDEWEB)

    Weng, Chuan-Bo, E-mail: send007@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); School of Neurosurgery, Anhui Medical University, 81 Meishang Road, Hefei, Anhui Province 230032 (China); Qian, Ruo-Bing, E-mail: rehomail@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China); Fu, Xian-Ming, E-mail: 506537677@qq.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China); Lin, Bin, E-mail: 274722758@qq.com [School of Neurosurgery, Anhui Medical University, 81 Meishang Road, Hefei, Anhui Province 230032 (China); Han, Xiao-Peng, E-mail: hanxiaopeng@163.com [Department of Psychology, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Niu, Chao-Shi, E-mail: niuchaoshi@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China); Wang, Ye-Han, E-mail: wangyehan@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China)

    2013-08-15

    Online game addiction (OGA) has attracted greater attention as a serious public mental health issue. However, there are only a few brain magnetic resonance imaging studies on brain structure about OGA. In the current study, we used voxel-based morphometry (VBM) analysis and tract-based spatial statistics (TBSS) to investigate the microstructural changes in OGA and assessed the relationship between these morphology changes and the Young's Internet Addiction Scale (YIAS) scores within the OGA group. Compared with healthy subjects, OGA individuals showed significant gray matter atrophy in the right orbitofrontal cortex, bilateral insula, and right supplementary motor area. According to TBSS analysis, OGA subjects had significantly reduced FA in the right genu of corpus callosum, bilateral frontal lobe white matter, and right external capsule. Gray matter volumes (GMV) of the right orbitofrontal cortex, bilateral insula and FA values of the right external capsule were significantly positively correlated with the YIAS scores in the OGA subjects. Our findings suggested that microstructure abnormalities of gray and white matter were present in OGA subjects. This finding may provide more insights into the understanding of the underlying neural mechanisms of OGA.

  17. Gray matter and white matter abnormalities in online game addiction.

    Science.gov (United States)

    Weng, Chuan-Bo; Qian, Ruo-Bing; Fu, Xian-Ming; Lin, Bin; Han, Xiao-Peng; Niu, Chao-Shi; Wang, Ye-Han

    2013-08-01

    Online game addiction (OGA) has attracted greater attention as a serious public mental health issue. However, there are only a few brain magnetic resonance imaging studies on brain structure about OGA. In the current study, we used voxel-based morphometry (VBM) analysis and tract-based spatial statistics (TBSS) to investigate the microstructural changes in OGA and assessed the relationship between these morphology changes and the Young's Internet Addiction Scale (YIAS) scores within the OGA group. Compared with healthy subjects, OGA individuals showed significant gray matter atrophy in the right orbitofrontal cortex, bilateral insula, and right supplementary motor area. According to TBSS analysis, OGA subjects had significantly reduced FA in the right genu of corpus callosum, bilateral frontal lobe white matter, and right external capsule. Gray matter volumes (GMV) of the right orbitofrontal cortex, bilateral insula and FA values of the right external capsule were significantly positively correlated with the YIAS scores in the OGA subjects. Our findings suggested that microstructure abnormalities of gray and white matter were present in OGA subjects. This finding may provide more insights into the understanding of the underlying neural mechanisms of OGA. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  18. Effective Field Theory of Majorana Dark Matter

    OpenAIRE

    Han, Huayong; WU, HONGYAN; Zheng, Sibo

    2017-01-01

    Thermal Majorana dark matter is explored from the viewpoint of effective field theory. Completely analytic result for dark matter annihilation into standard model background is derived in order to account relic density. The parameter space subject to the latest LUX, PandaX-II and Xenon-1T limits is shown in a model-independent way. For illustration, applications to singlet-doublet and neutralino dark matter are work out.

  19. Condensed Matter Physics

    Science.gov (United States)

    Marder, Michael P.

    2000-01-01

    A modern, unified treatment of condensed matter physics This new work presents for the first time in decades a sweeping review of the whole field of condensed matter physics. It consolidates new and classic topics from disparate sources, teaching "not only about the effective masses of electrons in semiconductor crystals and band theory, but also about quasicrystals, dynamics of phase separation, why rubber is more floppy than steel, electron interference in nanometer-sized channels, and the quantum Hall effect." Six major areas are covered---atomic structure, electronic structure, mechanical properties, electron transport, optical properties, and magnetism. But rather than defining the field in terms of particular materials, the author focuses on the way condensed matter physicists approach physical problems, combining phenomenology and microscopic arguments with information from experiments. For graduate students and professionals, researchers and engineers, applied mathematicians and materials scientists, Condensed Matter Physics provides: * An exciting collection of new topics from the past two decades. * A thorough treatment of classic topics, including band theory, transport theory, and semiconductor physics. * Over 300 figures, incorporating many images from experiments. * Frequent comparison of theory and experiment, both when they agree and when problems are still unsolved. * More than 50 tables of data and a detailed index. * Ample end-of-chapter problems, including computational exercises. * Over 1000 references, both recent and historically significant.

  20. Play Matters

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    ? In Play Matters, Miguel Sicart argues that to play is to be in the world; playing is a form of understanding what surrounds us and a way of engaging with others. Play goes beyond games; it is a mode of being human. We play games, but we also play with toys, on playgrounds, with technologies and design......, but not necessarily fun. Play can be dangerous, addictive, and destructive. Along the way, Sicart considers playfulness, the capacity to use play outside the context of play; toys, the materialization of play--instruments but also play pals; playgrounds, play spaces that enable all kinds of play; beauty...

  1. Particle Dark Matter (1/4)

    CERN Document Server

    CERN. Geneva

    2011-01-01

    I review the phenomenology of particle dark matter, including the process of thermal freeze-out in the early universe, and the direct and indirect detection of WIMPs. I also describe some of the most popular particle candidates for dark matter and summarize the current status of the quest to discover dark matter's particle identity.

  2. 40 CFR 1508.19 - Matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Matter. 1508.19 Section 1508.19 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.19 Matter. Matter includes for purposes of part 1504: (a) With respect to the Environmental Protection Agency, any proposed...

  3. Teaching Evolution: Do State Standards Matter?

    Science.gov (United States)

    Moore, Randy

    2002-01-01

    Explores the relationship of state standards for the teaching of evolution to the actual teaching of that subject. Compares a grading of states for their performance and discusses the question of whether state standards matter. (MM)

  4. Magnetisation transfer measurements of the subcortical grey and white matter in Parkinson's disease with and without dementia and in progressive supranuclear palsy

    Energy Technology Data Exchange (ETDEWEB)

    Hanyu, H.; Asano, T.; Sakurai, H.; Takasaki, M. [Dept. of Geriatric Medicine, Tokyo Medical University (Japan); Shindo, H.; Abe, K. [Dept. of Radiology, Tokyo Medical University (Japan)

    2001-07-01

    We measured the magnetisation transfer ratio (MTR) in the subcortical grey and white matter of 11 patients with idiopathic Parkinson's disease (PD) without dementia, six with PD with dementia (PDD), six with progressive supranuclear palsy (PSP), and 12 elderly control subjects to assess regional differences in structural brain damage. There were no significant differences in MTR in any region between PD and controls. However, patients with PDD had significantly lower MTR in the subcortical white matter, including the frontal white matter and the genu of the corpus callosum than the controls, whereas PSP had significantly lower MTR in the subcortical grey matter, including the putamen, globus pallidus and thalamus, in addition to the subcortical white matter. This suggests that regional patterns of structural brain damage can be detected using the magnetisation transfer technique. Measurement of MTR in the subcortical grey and white matter may be useful in differential diagnosis. (orig.)

  5. Communication About Sexual Matters With Women Attending a Danish Fertility Clinic: A Descriptive Study

    DEFF Research Database (Denmark)

    Fiil Eldridge, Katrine; Giraldi, Annamaria

    2017-01-01

    in their sexual life. Aim: To investigate how women at a fertility clinic desire and experience communication about sexual matters with doctors and to investigate the sexual function of these women. Methods: A cross-sectional self-administered questionnaire survey of women attending a Danish fertility clinic over...... 4 months was performed. Descriptive statistics were calculated and presented as frequencies. Main Outcome Measure: Communication about sexual matters with doctors included the women’s comfort, preferred and actual frequency of discussion, and initiation of the conversation. Sexual function included...... for discussing sexual matters, and greater communication on this subject needs to be clinically implemented. Eldridge KE, Giraldi A. Communication About Sexual Matters With Women Attending a Danish Fertility Clinic. A Descriptive Study. Sex Med 2017;5:e196ee202....

  6. Directly detecting Isospin-Violating Dark Matter

    OpenAIRE

    Kelso, Chris; Kumar, Jason; Marfatia, Danny; Sandick, Pearl

    2017-01-01

    We consider the prospects for multiple dark matter direct detection experiments to determine if the interactions of a dark matter candidate are isospin-violating. We focus on theoretically well-motivated examples of isospin-violating dark matter (IVDM), including models in which dark matter interactions with nuclei are mediated by a dark photon, a Z, or a squark. We determine that the best prospects for distinguishing IVDM from the isospin-invariant scenario arise in the cases of dark photon-...

  7. Mimicking Dark Matter

    OpenAIRE

    Bel, Lluís

    2017-01-01

    I show that a very simple model in the context of Newtonian physics promoted to a first approximation of general relativity can mimic Dark matter and explain most of its intriguing properties. Namely: i) Dark matter is a halo associated to ordinary matter; ii) Dark matter does not interact with ordinary matter nor with itself; iii) Its influence grows with the size of the aggregate of ordinary matter that is considered, and iv) Dark matter influences the propagation of light.

  8. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  9. Soft Matter Characterization

    CERN Document Server

    Borsali, Redouane

    2008-01-01

    Progress in basic soft matter research is driven largely by the experimental techniques available. Much of the work is concerned with understanding them at the microscopic level, especially at the nanometer length scales that give soft matter studies a wide overlap with nanotechnology. This 2 volume reference work, split into 4 parts, presents detailed discussions of many of the major techniques commonly used as well as some of those in current development for studying and manipulating soft matter. The articles are intended to be accessible to the interdisciplinary audience (at the graduate student level and above) that is or will be engaged in soft matter studies or those in other disciplines who wish to view some of the research methods in this fascinating field. Part 1 contains articles with a largely (but, in most cases, not exclusively) theoretical content and/or that cover material relevant to more than one of the techniques covered in subsequent volumes. It includes an introductory chapter on some of t...

  10. Chromatin as active matter

    Science.gov (United States)

    Agrawal, Ankit; Ganai, Nirmalendu; Sengupta, Surajit; Menon, Gautam I.

    2017-01-01

    Active matter models describe a number of biophysical phenomena at the cell and tissue scale. Such models explore the macroscopic consequences of driving specific soft condensed matter systems of biological relevance out of equilibrium through ‘active’ processes. Here, we describe how active matter models can be used to study the large-scale properties of chromosomes contained within the nuclei of human cells in interphase. We show that polymer models for chromosomes that incorporate inhomogeneous activity reproduce many general, yet little understood, features of large-scale nuclear architecture. These include: (i) the spatial separation of gene-rich, low-density euchromatin, predominantly found towards the centre of the nucleus, vis a vis. gene-poor, denser heterochromatin, typically enriched in proximity to the nuclear periphery, (ii) the differential positioning of individual gene-rich and gene-poor chromosomes, (iii) the formation of chromosome territories, as well as (iv), the weak size-dependence of the positions of individual chromosome centres-of-mass relative to the nuclear centre that is seen in some cell types. Such structuring is induced purely by the combination of activity and confinement and is absent in thermal equilibrium. We systematically explore active matter models for chromosomes, discussing how our model can be generalized to study variations in chromosome positioning across different cell types. The approach and model we outline here represent a preliminary attempt towards a quantitative, first-principles description of the large-scale architecture of the cell nucleus.

  11. Visual Impairment, Including Blindness

    Science.gov (United States)

    ... Who Knows What? (log-in required) Select Page Visual Impairment, Including Blindness Mar 31, 2017 Links updated, ... doesn’t wear his glasses. Back to top Visual Impairments in Children Vision is one of our ...

  12. Play Matters

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    What do we think about when we think about play? A pastime? Games? Childish activities? The opposite of work? Think again: If we are happy and well rested, we may approach even our daily tasks in a playful way, taking the attitude of play without the activity of play. So what, then, is play......, but not necessarily fun. Play can be dangerous, addictive, and destructive. Along the way, Sicart considers playfulness, the capacity to use play outside the context of play; toys, the materialization of play--instruments but also play pals; playgrounds, play spaces that enable all kinds of play; beauty......? In Play Matters, Miguel Sicart argues that to play is to be in the world; playing is a form of understanding what surrounds us and a way of engaging with others. Play goes beyond games; it is a mode of being human. We play games, but we also play with toys, on playgrounds, with technologies and design...

  13. Maxwell Matters

    CERN Document Server

    Eisenberg, Bob

    2016-01-01

    Charges are everywhere because most atoms are charged. Chemical bonds are formed by electrons with their charge. Charges move and interact according to Maxwell's equations in space and in atoms where the equations of electrodynamics are embedded in Schroedinger's equation as the potential. Maxwell's equations are universal, valid inside atoms and between stars from times much shorter than those of atomic motion (0.1 femtoseconds) to years (32 mega-seconds). Maxwell's equations enforce the conservation of current. Analysis shows that the electric field can take on whatever value is needed to ensure conservation of current. The properties of matter rearrange themselves to satisfy Maxwell's equations and conservation of current. Conservation of current is as universal as Maxwell's equations themselves. Yet equations of electrodynamics find little place in the literature of material physics, chemistry, or biochemistry. Kinetic models of chemistry and Markov treatments of atomic motion are ordinary differential eq...

  14. Play Matters

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    What do we think about when we think about play? A pastime? Games? Childish activities? The opposite of work? Think again: If we are happy and well rested, we may approach even our daily tasks in a playful way, taking the attitude of play without the activity of play. So what, then, is play......? In Play Matters, Miguel Sicart argues that to play is to be in the world; playing is a form of understanding what surrounds us and a way of engaging with others. Play goes beyond games; it is a mode of being human. We play games, but we also play with toys, on playgrounds, with technologies and design......, but not necessarily fun. Play can be dangerous, addictive, and destructive. Along the way, Sicart considers playfulness, the capacity to use play outside the context of play; toys, the materialization of play--instruments but also play pals; playgrounds, play spaces that enable all kinds of play; beauty...

  15. Subjects, Models, Languages, Transformations

    NARCIS (Netherlands)

    Rensink, Arend; Bézivin, J.; Heckel, R.

    2005-01-01

    Discussions about model-driven approaches tend to be hampered by terminological confusion. This is at least partially caused by a lack of formal precision in defining the basic concepts, including that of "model" and "thing being modelled" - which we call subject in this paper. We propose a minimal

  16. Barron's SAT subject test

    CERN Document Server

    Jansen, MA, Robert

    2016-01-01

    Includes one diagnostic test and three complete tests, all questions answered and explained, self-assessment guides, and subject reviews. Also features test strategies, QR codes to short instructional videos, and a detailed appendix with equations, physical constants, and a basic math review.

  17. Why Networking matters?

    Directory of Open Access Journals (Sweden)

    Romulus OPRICA

    2012-01-01

    Full Text Available The business bureaucracy, in general, makes the majority of the managers (both top and middle management neglect a key matter of success (both personal and businesslike: networking. The present paper wishes to raise a series of questions regarding Herminia Ibarra’s theory referring to the networking styles of managers on the basis of her own research on a series of managers included in the „100 top young managers” catalogue of Business Magazin.

  18. Why Networking matters?

    OpenAIRE

    Romulus OPRICA

    2012-01-01

    The business bureaucracy, in general, makes the majority of the managers (both top and middle management) neglect a key matter of success (both personal and businesslike): networking. The present paper wishes to raise a series of questions regarding Herminia Ibarra’s theory referring to the networking styles of managers on the basis of her own research on a series of managers included in the „100 top young managers” catalogue of Business Magazin.

  19. Crime and Criminal Law as a Theme in Education. Paper on the Starting Points, Objectives, and Teaching Matter of a Series of Lessons Called "Crime and Criminal Law," as a Theme for the School Subject of Social and Political Studies.

    Science.gov (United States)

    Hooghoff, Hans

    This series of lessons is intended to help high school students in the Netherlands consider how they look at, react to, and judge criminal events. The first part of the publication discusses different teaching approaches used in the lessons. These include: (1) a business analysis--study of the organization and structure of the criminal…

  20. Listening to Include

    Science.gov (United States)

    Veck, Wayne

    2009-01-01

    This paper attempts to make important connections between listening and inclusive education and the refusal to listen and exclusion. Two lines of argument are advanced. First, if educators and learners are to include each other within their educational institutions as unique individuals, then they will need to listen attentively to each other.…

  1. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  2. Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease?

    Science.gov (United States)

    Duncan, Gordon W; Firbank, Michael J; Yarnall, Alison J; Khoo, Tien K; Brooks, David J; Barker, Roger A; Burn, David J; O'Brien, John T

    2016-01-01

    The aim of this work was to investigate the cortical and white matter changes that underlie cognitive impairment in patients with incident Parkinson's disease (PD) disease using voxel-based morphometry and diffusion tensor imaging. Newly diagnosed nondemented PD (n = 125) and control subjects (n = 50) were recruited from the Incidence of Cognitive Impairment in Cohorts with Longitudinal Evaluation in Parkinson's Disease Study and completed cognitive assessments and 3T structural and diffusion tensor MR imaging. Voxel-based morphometry was performed to investigate the relationship between gray matter volume and cognitive ability. Microstructural white matter changes were assessed with diffusion tensor imaging measures of fractional anisotropy and mean diffusivity using tract-based spatial statistics. Increased mean diffusivity was observed bilaterally in subjects with PD, relative to controls (P = 0.019). Increased mean diffusivity was associated with performance on the semantic fluency and Tower of London tasks in frontal and parietal white matter tracts, including the cingulum, superior longitudinal fasciculus, inferior longitudinal fasciculus, and inferior fronto-occipital fasciculus. There was no difference in total gray matter volume between groups; however, bilateral reductions in frontal and parietal gray matter volume were associated with reduced performance on measures of executive function in PD subjects. At the earliest stages of PD, regionally specific increases in central white matter mean diffusivity are present and suggest early axonal damage. Such changes are not accompanied by significant gray matter volume loss and are consistent with proposed models of pathological progression of the disease. Structural MRI, especially diffusion tensor imaging analysis, offers potential as a noninvasive biomarker reflecting cognitive impairment in PD. © 2015 International Parkinson and Movement Disorder Society.

  3. Culture Matters

    Directory of Open Access Journals (Sweden)

    Gillian Warner-Søderholm

    2012-12-01

    Full Text Available Whether managers are concerned with financial issues, marketing, or human resource management (HRM, cultural values and practices do matter. The purpose of this article is to understand Norwegian managers’ cultural values within the cross-cultural landscape of her neighbors in the “Scandinavian cluster.” Clearly, subtle but disturbing differences may surface even when representatives from similar cultures work together. As a follow on from the GLOBE project, data based on the GLOBE instrument were collected on culture and communication values in Norway from 710 Norwegian middle managers for this present study. Although the Scandinavian cultures appear ostensibly similar, the results illustrate that research can reveal subtle but important cultural differences in nations that are similar yet dissimilar. All three Scandinavian societies appear intrinsically egalitarian; they appear to value low Power Distance, directness, and consensus in decision making and to promote Gender Egalitarianism. Nevertheless, there are significant differences in the degrees of commitment to these values by each individual Scandinavian partner. These differences need to be understood and appreciated to avoid misunderstandings.

  4. Rigid particulate matter sensor

    Science.gov (United States)

    Hall, Matthew [Austin, TX

    2011-02-22

    A sensor to detect particulate matter. The sensor includes a first rigid tube, a second rigid tube, a detection surface electrode, and a bias surface electrode. The second rigid tube is mounted substantially parallel to the first rigid tube. The detection surface electrode is disposed on an outer surface of the first rigid tube. The detection surface electrode is disposed to face the second rigid tube. The bias surface electrode is disposed on an outer surface of the second rigid tube. The bias surface electrode is disposed to face the detection surface electrode on the first rigid tube. An air gap exists between the detection surface electrode and the bias surface electrode to allow particulate matter within an exhaust stream to flow between the detection and bias surface electrodes.

  5. Light, Matter, and Geometry

    DEFF Research Database (Denmark)

    Frisvad, Jeppe Revall

    2008-01-01

    This thesis is about physically-based modelling of the appearance of materials. When a material is graphically rendered, its appearance is computed by considering the interaction of light and matter at a macroscopic level. In particular, the shape and the macroscopic optical properties...... of the material determine how it will interact with incident illumination. In this thesis the macroscopic optical properties are connected to the microscopic physical theories of light and matter. This enables prediction of the macroscopic optical properties of materials, and, consequently, also prediction...... of appearance based on the contents and the physical conditions of the materials. Physically-based appearance models have many potential input and output parameters. There are many choices that must be made: How many material components to include in the model, how many physical conditions to take into account...

  6. Functional renormalization group approach to neutron matter

    Directory of Open Access Journals (Sweden)

    Matthias Drews

    2014-11-01

    Full Text Available The chiral nucleon-meson model, previously applied to systems with equal number of neutrons and protons, is extended to asymmetric nuclear matter. Fluctuations are included in the framework of the functional renormalization group. The equation of state for pure neutron matter is studied and compared to recent advanced many-body calculations. The chiral condensate in neutron matter is computed as a function of baryon density. It is found that, once fluctuations are incorporated, the chiral restoration transition for pure neutron matter is shifted to high densities, much beyond three times the density of normal nuclear matter.

  7. Superconducting Detectors for Superlight Dark Matter.

    Science.gov (United States)

    Hochberg, Yonit; Zhao, Yue; Zurek, Kathryn M

    2016-01-08

    We propose and study a new class of superconducting detectors that are sensitive to O(meV) electron recoils from dark matter-electron scattering. Such devices could detect dark matter as light as the warm dark-matter limit, m(X)≳1  keV. We compute the rate of dark-matter scattering off of free electrons in a (superconducting) metal, including the relevant Pauli blocking factors. We demonstrate that classes of dark matter consistent with terrestrial and cosmological or astrophysical constraints could be detected by such detectors with a moderate size exposure.

  8. Being Included and Excluded

    DEFF Research Database (Denmark)

    Korzenevica, Marina

    2016-01-01

    Following the civil war of 1996–2006, there was a dramatic increase in the labor mobility of young men and the inclusion of young women in formal education, which led to the transformation of the political landscape of rural Nepal. Mobility and schooling represent a level of prestige that rural...... politics. It analyzes how formal education and mobility either challenge or reinforce traditional gendered norms which dictate a lowly position for young married women in the household and their absence from community politics. The article concludes that women are simultaneously excluded and included from...... people regard as a prerequisite for participating in local community politics. Based on a fieldwork in two villages of Panchthar district in eastern Nepal, this article explores how these changes strengthen or weaken women’s political agency and how this is reflected in their participation in community...

  9. Phases of cannibal dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Farina, Marco [New High Energy Theory Center, Department of Physics, Rutgers University,136 Frelinghuisen Road, Piscataway, NJ 08854 (United States); Pappadopulo, Duccio; Ruderman, Joshua T.; Trevisan, Gabriele [Center for Cosmology and Particle Physics, Department of Physics, New York University,New York, NY 10003 (United States)

    2016-12-13

    A hidden sector with a mass gap undergoes an epoch of cannibalism if number changing interactions are active when the temperature drops below the mass of the lightest hidden particle. During cannibalism, the hidden sector temperature decreases only logarithmically with the scale factor. We consider the possibility that dark matter resides in a hidden sector that underwent cannibalism, and has relic density set by the freeze-out of two-to-two annihilations. We identify three novel phases, depending on the behavior of the hidden sector when dark matter freezes out. During the cannibal phase, dark matter annihilations decouple while the hidden sector is cannibalizing. During the chemical phase, only two-to-two interactions are active and the total number of hidden particles is conserved. During the one way phase, the dark matter annihilation products decay out of equilibrium, suppressing the production of dark matter from inverse annihilations. We map out the distinct phenomenology of each phase, which includes a boosted dark matter annihilation rate, new relativistic degrees of freedom, warm dark matter, and observable distortions to the spectrum of the cosmic microwave background.

  10. Phases of cannibal dark matter

    Science.gov (United States)

    Farina, Marco; Pappadopulo, Duccio; Ruderman, Joshua T.; Trevisan, Gabriele

    2016-12-01

    A hidden sector with a mass gap undergoes an epoch of cannibalism if number changing interactions are active when the temperature drops below the mass of the lightest hidden particle. During cannibalism, the hidden sector temperature decreases only logarithmically with the scale factor. We consider the possibility that dark matter resides in a hidden sector that underwent cannibalism, and has relic density set by the freeze-out of two-to-two annihilations. We identify three novel phases, depending on the behavior of the hidden sector when dark matter freezes out. During the cannibal phase, dark matter annihilations decouple while the hidden sector is cannibalizing. During the chemical phase, only two-to-two interactions are active and the total number of hidden particles is conserved. During the one way phase, the dark matter annihilation products decay out of equilibrium, suppressing the production of dark matter from inverse annihilations. We map out the distinct phenomenology of each phase, which includes a boosted dark matter annihilation rate, new relativistic degrees of freedom, warm dark matter, and observable distortions to the spectrum of the cosmic microwave background.

  11. Introduction. Cosmology meets condensed matter.

    Science.gov (United States)

    Kibble, T W B; Pickett, G R

    2008-08-28

    At first sight, low-temperature condensed-matter physics and early Universe cosmology seem worlds apart. Yet, in the last few years a remarkable synergy has developed between the two. It has emerged that, in terms of their mathematical description, there are surprisingly close parallels between them. This interplay has been the subject of a very successful European Science Foundation (ESF) programme entitled COSLAB ('Cosmology in the Laboratory') that ran from 2001 to 2006, itself built on an earlier ESF network called TOPDEF ('Topological Defects: Non-equilibrium Field Theory in Particle Physics, Condensed Matter and Cosmology'). The articles presented in this issue of Philosophical Transactions A are based on talks given at the Royal Society Discussion Meeting 'Cosmology meets condensed matter', held on 28 and 29 January 2008. Many of the speakers had participated earlier in the COSLAB programme, but the strength of the field is illustrated by the presence also of quite a few new participants.

  12. INTERNATIONAL CONFERENCE ON ULTRASHORT HIGH-ENERGY RADIATION AND MATTER

    Energy Technology Data Exchange (ETDEWEB)

    Wootton, A J

    2004-01-15

    The workshop is intended as a forum to discuss the latest experimental, theoretical and computational results related to the interaction of high energy radiation with matter. High energy is intended to mean soft x-ray and beyond, but important new results from visible systems will be incorporated. The workshop will be interdisciplinary amongst scientists from many fields, including: plasma physics; x-ray physics and optics; solid state physics and material science; biology ; quantum optics. Topics will include, among other subjects: understanding damage thresholds for x-ray interactions with matter developing {approx} 5 keV x-ray sources to investigate damage; developing {approx} 100 keV Thomsom sources for material studies; developing short pulse (100 fs and less) x-ray diagnostics; developing novel X-ray optics; and developing models for the response of biological samples to ultra intense, sub ps x-rays high-energy radiation.

  13. Equilibrium Statistical Physics Phases of Matter and Phase Transitions

    CERN Document Server

    Baus, Marc

    2008-01-01

    This is a textbook which gradually introduces the student to the statistical mechanical study of the different phases of matter and to the phase transitions between them. Throughout, only simple models of both ordinary and soft matter are used but these are studied in full detail. The subject is developed in a pedagogical manner, starting from the basics, going from the simple ideal systems to the interacting systems, and ending with the more modern topics. The latter include the renormalisation group approach to critical phenomena, the density functional theory of interfaces, the topological defects of nematic liquid crystals and the kinematic aspects of the phase transformation process. This textbook provides the student with a complete overview, intentionally at an introductory level, of the theory of phase transitions. References include suggestions for more detailed treatments and four appendices supply overviews of the mathematical tools employed in the text.

  14. Matter, dark matter, and anti-matter in search of the hidden universe

    CERN Document Server

    Mazure, Alain

    2012-01-01

    For over ten years, the dark side of the universe has been headline news. Detailed studies of the rotation of spiral galaxies, and 'mirages' created by clusters of galaxies bending the light from very remote objects, have convinced astronomers of the presence of large quantities of dark (unseen) matter in the cosmos. Moreover, in the 1990s, it was discovered that some four to five billion years ago the expansion of the universe entered a phase of acceleration. This implies the existence of dark energy. The nature of these 'dark; ingredients remains a mystery, but they seem to comprise about 95 percent of the matter/energy content of the universe. As for ordinary matter, although we are immersed in a sea of dark particles, including primordial neutrinos and photons from 'fossil' cosmological radiation, both we and our environment are made of ordinary, baryonic matter. Strangely, even if 15-20 percent of matter is baryonic matter, this represents only 4-5 percent of the total matter/energy content of the cosmos...

  15. Industry Matters

    DEFF Research Database (Denmark)

    Tran, Angie Ngoc; Jeppesen, Søren

    2018-01-01

    regulation and greater industry pressure with regard to quality and safety of products than to labour standards in both sectors. Most factories in the TGF sector assembled products for global supply chains and were under pressure by industry norms, while most companies in the FBP sector produced......This chapter draws on a study investigating what corporate social responsibility (CSR) means to Vietnam’s small- and medium-size enterprise (SME) owner/managers and workers, using Scott’s three-pillar (norms, regulation, cognition) institutional framework. The findings are based on factory visits...... for the domestic market and were subjected to greater state regulation. Moreover, contributing critical perspectives to Scott’s framework, we found an overlap between the normative and the regulatory, and between the cognitive and the industry norms, which reveals how institutional and cultural pressures...

  16. The Dark Matter of Biology.

    Science.gov (United States)

    Ross, Jennifer L

    2016-09-06

    The inside of the cell is full of important, yet invisible species of molecules and proteins that interact weakly but couple together to have huge and important effects in many biological processes. Such "dark matter" inside cells remains mostly hidden, because our tools were developed to investigate strongly interacting species and folded proteins. Example dark-matter species include intrinsically disordered proteins, posttranslational states, ion species, and rare, transient, and weak interactions undetectable by biochemical assays. The dark matter of biology is likely to have multiple, vital roles to regulate signaling, rates of reactions, water structure and viscosity, crowding, and other cellular activities. We need to create new tools to image, detect, and understand these dark-matter species if we are to truly understand fundamental physical principles of biology. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  17. Physics matters

    CERN Document Server

    Natarajan, Vasant

    2017-01-01

    This is a collection of essays on physics topics. It is written as a textbook for non-physics science and arts students, at the undergraduate level. Topics covered include cellphone radiation, lasers, the twin paradox, and more.

  18. Media matters.

    Science.gov (United States)

    Martinez, L M

    1995-01-01

    The impact of the mass media on woman's status was addressed at two 1995 conferences: the Fourth World Conference on Women, held in Beijing, China, and the Congress of the World Association for Christian Communication, held in Puebla, Mexico. The globalization process facilitated by the mass media has served to increase the power of patriarchy, with no advantages to the cause of women's rights. Coverage of popular movements has been suppressed out of deference to male-controlled governments. Coverage of the Beijing Conference highlighted celebrities and personal stories, to the exclusion of the economic and political issues under debate. Television has commodified women, reinforcing their oppression. On the other hand, the alternative media, which tend to be decentralized, democratic, low-cost, and low in technology, are presenting women as subjects rather than objects and deconstructing gender stereotypes. Of concern, however, is the tendency of computer technology to widen the gap between social classes and developed and developing countries. Women must use information networks to disseminate information on women's rights and strengthen the links between women throughout the world.

  19. Thermodynamics of cosmological matter creation

    Science.gov (United States)

    Prigogine, I.; Geheniau, J.; Gunzig, E.; Nardone, P.

    1988-01-01

    A type of cosmological history that includes large-scale entropy production is proposed. These cosmologies are based on reinterpretation of the matter-energy stress tensor in Einstein's equations. This modifies the usual adiabatic energy conservation laws, thereby including irreversible matter creation. This creation corresponds to an irreversible energy flow from the gravitational field to the created matter constituents. This point of view results from consideration of the thermodynamics of open systems in the framework of cosmology. It is shown that the second law of thermodynamics requires that space-time transforms into matter, while the inverse transformation is forbidden. It appears that the usual initial singularity associated with the big bang is structurally unstable with respect to irreversible matter creation. The corresponding cosmological history therefore starts from an instability of the vacuum rather than from a singularity. This is exemplified in the framework of a simple phenomenological model that leads to a three-stage cosmology: the first drives the cosmological system from the initial instability to a de Sitter regime, and the last connects with the usual matter-radiation Robertson-Walker universe. Matter as well as entropy creation occurs during the first two stages, while the third involves the traditional cosmological evolution. A remarkable fact is that the de Sitter stage appears to be an attractor independent of the initial fluctuation. This is also the case for all the physical predictions involving the present Robertson-Walker universe. Most results obtained previously, in the framework of quantum field theory, can now be obtained on a macroscopic basis. It is shown that this description leads quite naturally to the introduction of primeval black holes as the intermediate stage between the Minkowski vacuum and the present matter-radiation universe. The instability at the origin of the universe is the result of fluctuations of the

  20. Thermodynamics of cosmological matter creation.

    Science.gov (United States)

    Prigogine, I; Geheniau, J; Gunzig, E; Nardone, P

    1988-10-01

    A type of cosmological history that includes large-scale entropy production is proposed. These cosmologies are based on reinterpretation of the matter-energy stress tensor in Einstein's equations. This modifies the usual adiabatic energy conservation laws, thereby including irreversible matter creation. This creation corresponds to an irreversible energy flow from the gravitational field to the created matter constituents. This point of view results from consideration of the thermodynamics of open systems in the framework of cosmology. It is shown that the second law of thermodynamics requires that space-time transforms into matter, while the inverse transformation is forbidden. It appears that the usual initial singularity associated with the big bang is structurally unstable with respect to irreversible matter creation. The corresponding cosmological history therefore starts from an instability of the vacuum rather than from a singularity. This is exemplified in the framework of a simple phenomenological model that leads to a three-stage cosmology: the first drives the cosmological system from the initial instability to a de Sitter regime, and the last connects with the usual matter-radiation Robertson-Walker universe. Matter as well as entropy creation occurs during the first two stages, while the third involves the traditional cosmological evolution. A remarkable fact is that the de Sitter stage appears to be an attractor independent of the initial fluctuation. This is also the case for all the physical predictions involving the present Robertson-Walker universe. Most results obtained previously, in the framework of quantum field theory, can now be obtained on a macroscopic basis. It is shown that this description leads quite naturally to the introduction of primeval black holes as the intermediate stage between the Minkowski vacuum and the present matter-radiation universe. The instability at the origin of the universe is the result of fluctuations of the

  1. This data set represents the estimated percentage of the 1-km grid cell that is covered by or subject to the agricultural conservation practice (CPIS04), Stream, Lagoon or Other Waste Waster (not including tailwater recovery) as an Irrigation Source (LWWIS) on agricultural land by county (nri_is04)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set represents the estimated percentage of the 1-km grid cell that is covered by or subject to the agricultural conservation practice (CPIS04), Stream,...

  2. Malaria Matters

    Centers for Disease Control (CDC) Podcasts

    2008-04-18

    This podcast gives an overview of malaria, including prevention and treatment, and what CDC is doing to help control and prevent malaria globally.  Created: 4/18/2008 by National Center for Zoonotic, Vector-Borne, and Enteric Diseases (NCZVED).   Date Released: 4/18/2008.

  3. ADAPTIVE OUTPUT CONTROL: SUBJECT MATTER, APPLICATION TASKS AND SOLUTIONS

    Directory of Open Access Journals (Sweden)

    Alexey A. Bobtsov

    2013-01-01

    Full Text Available The problem of adaptive output control for parametric and functionally uncertain plants is considered. Application examples illustrating the practical use of the discussed theory are given along with the mathematical formulation of the problem. A brief review of adaptive output control methods, by both linear and non-linear systems, is presented and an extensive bibliography, in which the reader will find a detailed description of the specific algorithms and their properties, is represented. A new approach to the output control problem - a method of consecutive compensator - is considered in detail.

  4. K-Means Subject Matter Expert Refined Topic Model Methodology

    Science.gov (United States)

    2017-01-01

    implementations for Case 4 only. The accuracy results for all of the SMERT/KSMERT implantations are similar due to the user employing domain knowledge to...truck. 5 The supplier welded and misdimensioned the titanium offsite. 6 The inspector drilled plastic and overheated it at station2. 7 It was...drilled and overheated. 8 It was drilled and overheated. 9 The engineer and the manager at station3 and on the truck. 10 The welded titanium was

  5. Applying Subject Matter Expertise (SME) Elicitation Techniques to TRAC Studies

    Science.gov (United States)

    2014-09-30

    in different ways. In the first case, CPR Analisys , we use the measures as way to derive effectiveness and uncertainty. In the second approach...means by which to overcome these capability gaps through the implementation of solutions, e.g., changes to doctrine, organizational structure , training...controlled through good elicitation practices, especially good question structuring , which we discuss in section C. (2) Modeling bias. This type of bias

  6. Writing for professional publication. Part 2: Subject matter.

    Science.gov (United States)

    Fowler, John

    Motivation is the first step in writing for professional publication: the next question is, what should you write about? Whatever your area of practice or level of experience, your writing will be suitable for one of the wealth of journals covering all aspects of healthcare and nursing. In this second part of a series of articles, John Fowler, an experienced nursing lecturer and author, presents some tips and suggestions to inspire you as you take your first steps on the road to writing for professional publication.

  7. Classification of educational subject matter: the case of Home ...

    African Journals Online (AJOL)

    Although it represents an individual view, this article was submitted to the Department of Education by the Cape Higher Education Consortium (CHEC) as an outcome of the review of the field of Home Economics in the Western Cape region. By presenting some history, it argues that the category of Home Economics is no ...

  8. RAn Enlarged Conception of the Subject Matter of Logic

    Directory of Open Access Journals (Sweden)

    John T. Kearns

    2004-01-01

    Full Text Available Una concepción ampliada del objeto de estudio de la lógica: El ensayo es una introducción a la lógica ilocucionaria, es decir a la lógica de los actos de habla. El autor propone una aproximación distinta a este campo de investigación con respecto al que han propuesto John Searle y Daniel Vanderveken. Ellos conciben la lógica ilocucionaria como un suplemento o un apéndice a la lógica estándar, la lógica de los enunciados, y se concentran en el estudio de leyes y principios muy generales que caracterizan todo tipo de actos ilocucionarios. Kearns, en cambio, concibe la lógica ilocucionaria como una disciplina muy comprensiva, con muchos subsistemas, que cobija a la lógica estándar como parte suya. El escrito describe brevemente el uso de los operadores ilocucionarios (de aseveración, de negación, de suposición de verdad o falsedad, explica la manera como se expande la concepción semántica en términos de condiciones de verdad para incluir los compromisos racionales del hablante y presenta un sistema de deducción para esta lógica. Como un ejemplo de lo que esta lógica puede hacer se ofrece una solución a la paradoja de Moore contenida en la aseveración “Está lloviendo, pero no lo creo”

  9. Occupational Listings Arranged by Cluster and Subject Matter Areas.

    Science.gov (United States)

    Schwarz, Otto

    Approximately 850 occupations are listed under 27 occupational clusters. The Dictionary of Occupational Title (DOT) number is specified for occupations in the clusters of business training and distributive education, chemistry, general shop and industrial arts, home economics, foreign language, music, social studies, art, agriculture, physics, and…

  10. Instructional Design: Impact of Subject Matter and Cognitive Styles.

    Science.gov (United States)

    1987-02-01

    processing, and the integration/synthesis of component parts. The haptic individual uses " bodily " perceptions, and is kinesthetically oriented. An...microcomputers, and the introduction of artificial intelligence techniques into training has permitted more effective use of computer-based instruction...instruction, the advent of more powerful and inexpensive microcomputers, and the introduction of artificial intelligence techniques into training, has permitted

  11. Does tutor subject-matter expertise influence student achievement in ...

    African Journals Online (AJOL)

    The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

  12. The role of subject-matter analysis in science didactics

    DEFF Research Database (Denmark)

    Chaiklin, Seth

    to problems within science education. STEM education research can be reduced (roughly) to four major problem areas: curriculum, empirical evaluation of existing practices and conditions, didactics, and professional development, where each of these categories can be concretised further according to grade...... paper is primarily on the didactics category, and slightly on the professional development category. The purpose of this paper is to outline three significant points that have been developed within the cultural-historical tradition that have consequences for these two categories: (a) the relation...

  13. Blending critical thinking skills with the teaching of subject matter ...

    African Journals Online (AJOL)

    The study draws on Piaget and Vygotsky's theory of (social) constructivism to advance approaches and practices that teachers can employ to promote critical thinking in learners. We develop a lesson plan that incorporates critical thinking skills and show how teachers can correct egocentric and sociocentric tendencies that ...

  14. Cosmology and Dark Matter

    CERN Document Server

    Tkachev, Igor

    2017-01-01

    This lecture course covers cosmology from the particle physicist perspective. Therefore, the emphasis will be on the evidence for the new physics in cosmological and astrophysical data together with minimal theoretical frameworks needed to understand and appreciate the evidence. I review the case for non-baryonic dark matter and describe popular models which incorporate it. In parallel, the story of dark energy will be developed, which includes accelerated expansion of the Universe today, the Universe origin in the Big Bang, and support for the Inflationary theory in CMBR data.

  15. Management does matter

    DEFF Research Database (Denmark)

    Kroustrup, Jonas

    The positivist and managerialist approaches to project management research has historically defined practice as a ‘technical’ discipline. This has recently been challenged by critical project management studies, who advocates for an opening of the field research to also include the social...... studies approach the paper acknowledges that management and project management technologies does matter, but comes in many shapes, and is performed differently in various socio-technical settings. The field of STS offers a new ground for a participatory and practice oriented approach to the development...

  16. 42 CFR 1008.15 - Facts subject to advisory opinions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Facts subject to advisory opinions. 1008.15 Section... Requesting Party § 1008.15 Facts subject to advisory opinions. (a) The OIG will consider requests from a requesting party for advisory opinions regarding the application of specific facts to the subject matters set...

  17. Academic Training: The World of Quantum Matter

    CERN Multimedia

    Françoise Benz

    2006-01-01

    2005-2006 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 23, 24, 25, 26 January 2006 from 11:00 to 12:00 - Main Auditorium, bldg. 500 The World of Quantum Matter M. WEIDEMUELLER / Albert-Ludwigs-Universität Freiburg In my lecture series, I will present the recent spectacular advances in the field of quantum gases and macroscopic quantum physics. A variety of subjects will be covered including Bose condensates and degenerate Fermi gases, ultracold molecules and chemistry near absolute zero, Rydberg gases, single-atom manipulation, quantum information processing, as well as applications of cold atoms as precision targets. The topics of the lectures are: Physics near absolute zero Bose condensation and Fermi degeneracy Molecules, Rydberg gases and other exotic species Single-atom manipulation, quantum information processing and ultracold atoms as targets in storage rings. ENSEIGNEMENT ACADEMIQUE ACADEMIC TRAINING Françoise Benz 73127 academic.training@cern.ch If you wish to participate in one of the f...

  18. Multiple sclerosis: white and gray matter damage associated with balance deficit detected at static posturography.

    Science.gov (United States)

    Prosperini, Luca; Sbardella, Emilia; Raz, Eytan; Cercignani, Mara; Tona, Francesca; Bozzali, Marco; Petsas, Nikolaos; Pozzilli, Carlo; Pantano, Patrizia

    2013-07-01

    To combine two unbiased (ie, without any a priori hypothesis) magnetic resonance (MR) imaging processing approaches, tract-based spatial statistics and voxel-based morphometry, to investigate the relationship between white matter and gray matter damage and computer-based measures of balance impairment assessed at static posturography in patients with multiple sclerosis (MS). Institutional review board approval and written informed consent were obtained. Forty-five ambulatory patients with MS (34 women, 11 men) and 25 sex- and age-matched healthy control subjects were assessed by using a force platform to compute the displacement (in millimeters) of the body center of pressure in 30 seconds. In a separate session, patients underwent MR imaging at 3 T, including a dual-echo fast spin-echo sequence, a T1-weighted volume sequence, and a diffusion-tensor imaging sequence. T2 lesion volumes were assessed by using a semiautomated technique. Tract-based spatial statistics and voxel-based morphometry were used for the white and gray matter analyses, respectively, to correlate force platform measures with diffusion-tensor imaging parameters and regional gray matter volumes, adjusting for the patients' sex, age, disease duration, and lesion volume. Patients with MS had worse postural stability, widespread alterations in most white matter bundles, and gray matter atrophy in several brain regions compared with control subjects. In patients with MS, balance impairment was correlated with worse diffusion-tensor imaging parameters along the cerebellar connections and supratentorial associative white matter bundles (P matter atrophy of the superior lobules of the cerebellum (IV, V, VI), and lobules VIII also correlated with worse posturometric values (P < .05, family-wise error corrected). Imbalance due to MS appears to be related to the disconnection between the spinal cord, cerebellum, and cerebral cortex, which in turn produces atrophy of the sensory motor cerebellar regions

  19. Soft Condensed Matter

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Richard A L

    2002-11-20

    phenomenologically and formulated through the current percolation model and the Flory-Stockmayer model. The next two chapters consider the molecular order in soft condensed matter. The rich complexity of liquid crystals is emphasized and the Frederiks transition is described in relation to liquid crystal displays. The crystallinity in polymers is discussed and its usual semi-crystallinity presented as a consequence of entanglement and timescales. The next chapter describes the self-assembly of phases and the great importance of the self-assembly phenomenon in solutions of amphiphilic molecules is largely discussed in several specific phenomena. The book ends with a chapter devoted to the description of soft matter realizations in nature. Special attention is paid to the components and structure of life: nucleic acids, proteins, polysaccharides and membranes. There are two appendixes recalling the basic concepts of thermodynamics and statistical mechanics. In each chapter, several problems are included, and solutions to a selection of them are given. The bibliography proposed is pertinent and each chapter gives details of further reading, mostly addressed to known books on the topic. The presentation of the book is good. Throughout the book, the relevant, basic or new concepts of each topic are typed in bold characters and succinctly defined. The figures are abundant and adequately illustrate the text either by plots of experimental data or by computed predictions from models. Many schematic representations of structures, molecular distributions or arrangements are also included. In summary, the author has succeeded in producing a scientifically rigorous book of affordable size (around 200 pages) that is well illustrated (about 120 figures) and written in a fluent style that describes the many different physical phenomena involved in soft condensed matter. (book review)

  20. Enlightening Students about Dark Matter

    Science.gov (United States)

    Hamilton, Kathleen; Barr, Alex; Eidelman, Dave

    2018-01-01

    Dark matter pervades the universe. While it is invisible to us, we can detect its influence on matter we can see. To illuminate this concept, we have created an interactive javascript program illustrating predictions made by six different models for dark matter distributions in galaxies. Students are able to match the predicted data with actual experimental results, drawn from several astronomy papers discussing dark matter’s impact on galactic rotation curves. Programming each new model requires integration of density equations with parameters determined by nonlinear curve-fitting using MATLAB scripts we developed. Using our javascript simulation, students can determine the most plausible dark matter models as well as the average percentage of dark matter lurking in galaxies, areas where the scientific community is still continuing to research. In that light, we strive to use the most up-to-date and accepted concepts: two of our dark matter models are the pseudo-isothermal halo and Navarro-Frenk-White, and we integrate out to each galaxy’s virial radius. Currently, our simulation includes NGC3198, NGC2403, and our own Milky Way.

  1. Pedogenesis evolution of mine technosols: focus onto organic matter implication

    Science.gov (United States)

    Grégoire, Pascaud; Marilyne, Soubrand; Laurent, Lemee; Husseini Amelène, El-Mufleh Al; Marion, Rabiet; Emmanuel, Joussein

    2014-05-01

    Keywords: Mine technosols, pedogenesis, organic matter, environmental impact, pyr-GC-MS Technosols include soils subject to strong anthropogenic pressure and particularly to soil influenced by human transformed materials. In this context, abandoned mine sites contain a large amount of transformed waste materials often enriched with metals and/or metalloids. The natural evolution of technosols (pedogenesis) may induces the change in contaminants behaviour in term of stability of bearing phases, modification of pH oxydo-reduction conditions, organic matter turnover, change in permeability, or influence of vegetation cover. The fate of these elements in the soil can induce major environmental problems (contamination of biosphere and water resource). This will contribute to a limited potential use of these soils, which represent yet a large area around the world. The initial contamination of the parental material suggests that the pedological cover would stabilize the soil; however, the chemical reactivity must be taken in consideration particularly with respect to potential metal leachings. In this case, it is quite important to understand the development of soil in this specific context. Consequently, the global aims of this study are to understand the functioning of mine Technosols focusing onto the organic matter implication in their pedogenesis. Indeed, soil organic matter constitutes an heterogeneous fraction of organic compounds that plays an important role in the fate and the transport of metals and metalloids in soils. Three different soil profiles were collected representative to various mining context (contamination, time, climat), respectively to Pb-Ag, Sn and Au exploitations. Several pedological parameters were determined like CEC, pH, %Corg, %Ntot, C/N ratio, grain size distribution and chemical composition. The evolution of the nature of organic matter in Technosol was studied by elemental analyses and thermochemolysis was realized on the total and

  2. Behavior matters.

    Science.gov (United States)

    Fisher, Edwin B; Fitzgibbon, Marian L; Glasgow, Russell E; Haire-Joshu, Debra; Hayman, Laura L; Kaplan, Robert M; Nanney, Marilyn S; Ockene, Judith K

    2011-05-01

    Behavior has a broad and central role in health. Behavioral interventions can be effectively used to prevent disease, improve management of existing disease, increase quality of life, and reduce healthcare costs. A summary is presented of evidence for these conclusions in cardiovascular disease/diabetes, cancer, and HIV/AIDS as well as with key risk factors: tobacco use, poor diet, physical inactivity, and excessive alcohol consumption. For each, documentation is made of (1) moderation of genetic and other fundamental biological influences by behaviors and social-environmental factors; (2) impacts of behaviors on health; (3) success of behavioral interventions in prevention; (4) disease management; (5) quality of life, and (6) improvements in the health of populations through behavioral health promotion programs. Evidence indicates the cost effectiveness and value of behavioral interventions, especially relative to other common health services as well as the value they add in terms of quality of life. Pertinent to clinicians and their patients as well as to health policy and population health, the benefits of behavioral interventions extend beyond impacts on a particular disease or risk factor. Rather, they include broad effects and benefits on prevention, disease management, and well-being across the life span. Among priorities for dissemination research, the application of behavioral approaches is challenged by diverse barriers, including socioeconomic barriers linked to health disparities. However, behavioral approaches including those emphasizing community and social influences appear to be useful in addressing such challenges. In sum, behavioral approaches should have a central place in prevention and health care of the 21st century. Copyright © 2011 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  3. Family Matters

    Directory of Open Access Journals (Sweden)

    Isabel de Riquer

    2011-04-01

    Full Text Available The scene is at the court of James I of Aragon in the mid-13th c., the place is the royal palace of Barcelona or any of the crown's other possessions, and the dramatis personae include the heir to the throne, prince Peire (future king Peire the Great, and the court's most famous troubadour, Cerverí de Girona (fl. 1259-85. Author of the largest corpus of any Occitan troubadour (114 poems, Cerverì distinguishes himself by the surprises and challenges he presents to his audience: an alba (the most openly erotic genre to the Virgin Mary, the Cobla in sis lengatges (Cobla in Six Languages, the apparently nonsensical Vers estrayn. Cerverì borrows equally from the folk-inspired Galician-Portuguese poetry and from the French tradition, including the chanson de malmariée, where a young woman bemoans being sold off by her family to an old man (gilos, "Jealous" and separated from her youthful doulz amis, some even praying for the death of their husband. Both within that tradition and among Cerverì's three chansons de malmariée, the Gelosesca stands out as "especially determined" to lose her husband, using every "solution" (prayer, black magic, potion or experimenta.

  4. White matter microstructure correlates of mathematical giftedness and intelligence quotient.

    Science.gov (United States)

    Navas-Sánchez, Francisco J; Alemán-Gómez, Yasser; Sánchez-Gonzalez, Javier; Guzmán-De-Villoria, Juan A; Franco, Carolina; Robles, Olalla; Arango, Celso; Desco, Manuel

    2014-06-01

    Recent functional neuroimaging studies have shown differences in brain activation between mathematically gifted adolescents and controls. The aim of this study was to investigate the relationship between mathematical giftedness, intelligent quotient (IQ), and the microstructure of white matter tracts in a sample composed of math-gifted adolescents and aged-matched controls. Math-gifted subjects were selected through a national program based on detecting enhanced visuospatial abilities and creative thinking. We used diffusion tensor imaging to assess white matter microstructure in neuroanatomical connectivity. The processing included voxel-wise and region of interest-based analyses of the fractional anisotropy (FA), a parameter which is purportedly related to white matter microstructure. In a whole-sample analysis, IQ showed a significant positive correlation with FA, mainly in the corpus callosum, supporting the idea that efficient information transfer between hemispheres is crucial for higher intellectual capabilities. In addition, math-gifted adolescents showed increased FA (adjusted for IQ) in white matter tracts connecting frontal lobes with basal ganglia and parietal regions. The enhanced anatomical connectivity observed in the forceps minor and splenium may underlie the greater fluid reasoning, visuospatial working memory, and creative capabilities of these children. © 2013 Wiley Periodicals, Inc.

  5. Abiotic Bromination of Soil Organic Matter

    Energy Technology Data Exchange (ETDEWEB)

    Leri, Alessandra C.; Ravel, Bruce

    2015-11-17

    Biogeochemical transformations of plant-derived soil organic matter (SOM) involve complex abiotic and microbially mediated reactions. One such reaction is halogenation, which occurs naturally in the soil environment and has been associated with enzymatic activity of decomposer organisms. Building on a recent finding that naturally produced organobromine is ubiquitous in SOM, we hypothesized that inorganic bromide could be subject to abiotic oxidations resulting in bromination of SOM. Through lab-based degradation treatments of plant material and soil humus, we have shown that abiotic bromination of particulate organic matter occurs in the presence of a range of inorganic oxidants, including hydrogen peroxide and assorted forms of ferric iron, producing both aliphatic and aromatic forms of organobromine. Bromination of oak and pine litter is limited primarily by bromide concentration. Fresh plant material is more susceptible to bromination than decayed litter and soil humus, due to a labile pool of mainly aliphatic compounds that break down during early stages of SOM formation. As the first evidence of abiotic bromination of particulate SOM, this study identifies a mechanistic source of the natural organobromine in humic substances and the soil organic horizon. Formation of organobromine through oxidative treatments of plant material also provides insights into the relative stability of aromatic and aliphatic components of SOM.

  6. The structural neural substrate of subjective happiness.

    Science.gov (United States)

    Sato, Wataru; Kochiyama, Takanori; Uono, Shota; Kubota, Yasutaka; Sawada, Reiko; Yoshimura, Sayaka; Toichi, Motomi

    2015-11-20

    Happiness is a subjective experience that is an ultimate goal for humans. Psychological studies have shown that subjective happiness can be measured reliably and consists of emotional and cognitive components. However, the neural substrates of subjective happiness remain unclear. To investigate this issue, we used structural magnetic resonance imaging and questionnaires that assessed subjective happiness, the intensity of positive and negative emotional experiences, and purpose in life. We found a positive relationship between the subjective happiness score and gray matter volume in the right precuneus. Moreover, the same region showed an association with the combined positive and negative emotional intensity and purpose in life scores. Our findings suggest that the precuneus mediates subjective happiness by integrating the emotional and cognitive components of happiness.

  7. The structural neural substrate of subjective happiness

    Science.gov (United States)

    Sato, Wataru; Kochiyama, Takanori; Uono, Shota; Kubota, Yasutaka; Sawada, Reiko; Yoshimura, Sayaka; Toichi, Motomi

    2015-01-01

    Happiness is a subjective experience that is an ultimate goal for humans. Psychological studies have shown that subjective happiness can be measured reliably and consists of emotional and cognitive components. However, the neural substrates of subjective happiness remain unclear. To investigate this issue, we used structural magnetic resonance imaging and questionnaires that assessed subjective happiness, the intensity of positive and negative emotional experiences, and purpose in life. We found a positive relationship between the subjective happiness score and gray matter volume in the right precuneus. Moreover, the same region showed an association with the combined positive and negative emotional intensity and purpose in life scores. Our findings suggest that the precuneus mediates subjective happiness by integrating the emotional and cognitive components of happiness. PMID:26586449

  8. [Subjective cognition in schizophrenia].

    Science.gov (United States)

    Potvin, S; Aubin, G; Stip, E

    2017-02-01

    Given the extent, magnitude and functional significance of the neurocognitive deficits of schizophrenia, growing attention has been paid recently to patients' self-awareness of their own deficits. Thus far, the literature has shown either that patients fail to recognize their cognitive deficits or that the association between subjective and objective cognition is weak in schizophrenia. The reasons for this lack of consistency remain unexplained but may have to do, among others, with the influence of potential confounding clinical variables and the choice of the scale used to measure self-awareness of cognitive deficits. In the current study, we sought to examine the relationships between subjective and objective cognitive performance in schizophrenia, while controlling for the influence of sociodemographic and psychiatric variables. Eighty-two patients with a schizophrenia-spectrum disorder (DSM-IV criteria) were recruited. Patients' subjective cognitive complaints were evaluated with the Subjective Scale to Investigate Cognition in Schizophrenia (SSTICS), the most frequently used scale to measure self-awareness of cognitive deficits in schizophrenia. Neurocognition was evaluated with working memory, planning and visual learning tasks taken from Cambridge Neuropsychological Tests Automated Battery. The Stroop Color-Word test was also administered. Psychiatric symptoms were evaluated with the Positive and Negative Syndrome Scale and the Calgary Depression Scale for Schizophrenia. The relationships between subjective and objective cognition were evaluated with multivariate hierarchic linear regression analyses, taking into consideration potential confounders such as sociodemographic and psychiatric variables. Finally, a factor analysis of the SSTICS was performed. For the SSTICS total score, the regression analysis produced a model including two predictors, namely visual learning and Stoop interference performance, explaining a moderate portion of the variance

  9. White matter injury detection in neonatal MRI

    Science.gov (United States)

    Cheng, Irene; Hajari, Nasim; Firouzmanesh, Amirhossein; Shen, Rui; Miller, Steven; Poskitt, Ken; Basu, Anup

    2013-02-01

    Early detection of white matter injury in premature newborns can facilitate timely clinical treatments reducing the potential risk of later developmental deficits. It was reported that there were more than 5% premature newborns in British Columbia, Canada, among which 5-10% exhibited major motor deficits and 25-50% exhibited significant developmental and visual deficits. With the advancement of computer assisted detection systems, it is possible to automatically identify white matter injuries, which are found inside the grey matter region of the brain. Atlas registration has been suggested in the literature to distinguish grey matter from the soft tissues inside the skull. However, our subjects are premature newborns delivered at 24 to 32 weeks of gestation. During this period, the grey matter undergoes rapid changes and differs significantly from one to another. Besides, not all detected white spots represent injuries. Additional neighborhood information and expert input are required for verification. In this paper, we propose a white matter feature identification system for premature newborns, which is composed of several steps: (1) Candidate white matter segmentation; (2) Feature extraction from candidates; (3) Validation with data obtained at a later stage on the children; and (4) Feature confirmation for automated detection. The main challenge of this work lies in segmenting white matter injuries from noisy and low resolution data. Our approach integrates image fusion and contrast enhancement together with a fuzzy segmentation technique to achieve promising results. Other applications, such as brain tumor and intra-ventricular haemorrhage detection can also benefit from our approach.

  10. Phases of dense matter with holographic instantons

    Directory of Open Access Journals (Sweden)

    Preis Florian

    2017-01-01

    Full Text Available We discuss nuclear matter and the transition to quark matter in the decompactified limit of the Sakai-Sugimoto model. Nuclear matter is included through instantons on the flavor branes of the model. Our approximation is based on the flat-space solution, but we allow for a dynamical instanton width and deformation and compute the energetically preferred number of instanton layers in the bulk as a function of the baryon chemical potential. We determine the regions in parameter space where the binding energy of nuclear matter is like in QCD, and compute the phase diagram in the plane of temperature and chemical potential.

  11. Gray matter atrophy in narcolepsy: An activation likelihood estimation meta-analysis.

    Science.gov (United States)

    Weng, Hsu-Huei; Chen, Chih-Feng; Tsai, Yuan-Hsiung; Wu, Chih-Ying; Lee, Meng; Lin, Yu-Ching; Yang, Cheng-Ta; Tsai, Ying-Huang; Yang, Chun-Yuh

    2015-12-01

    The authors reviewed the literature on the use of voxel-based morphometry (VBM) in narcolepsy magnetic resonance imaging (MRI) studies via the use of a meta-analysis of neuroimaging to identify concordant and specific structural deficits in patients with narcolepsy as compared with healthy subjects. We used PubMed to retrieve articles published between January 2000 and March 2014. The authors included all VBM research on narcolepsy and compared the findings of the studies by using gray matter volume (GMV) or gray matter concentration (GMC) to index differences in gray matter. Stereotactic data were extracted from 8 VBM studies of 149 narcoleptic patients and 162 control subjects. We applied activation likelihood estimation (ALE) technique and found significant regional gray matter reduction in the bilateral hypothalamus, thalamus, globus pallidus, extending to nucleus accumbens (NAcc) and anterior cingulate cortex (ACC), left mid orbital and rectal gyri (BAs 10 and 11), right inferior frontal gyrus (BA 47), and the right superior temporal gyrus (BA 41) in patients with narcolepsy. The significant gray matter deficits in narcoleptic patients occurred in the bilateral hypothalamus and frontotemporal regions, which may be related to the emotional processing abnormalities and orexin/hypocretin pathway common among populations of patients with narcolepsy. Copyright © 2015. Published by Elsevier Ltd.

  12. Vanishing White Matter Disease

    Science.gov (United States)

    ... In Memory Of Obituaries Contact Us Donate Vanishing White Matter Disease What is Vanishing White Matter Disease? ... of the genetic basis of VWM was a great step forward. First of all, it allows genetic ...

  13. Particulate Matter (PM) Pollution

    Science.gov (United States)

    ... Environmental Protection Agency Search Search Particulate Matter (PM) Pollution Contact Us Share Most PM particles form in ... and cause serious health effects. Particulate Matter (PM) Pollution PM Basics What is PM, and how does ...

  14. Mind Over Matter: Cocaine

    Science.gov (United States)

    ... Term(s): Teachers / NIDA Teaching Guide / Mind Over Matter Teaching Guide and Series / Cocaine Mind Over Matter: Cocaine Print Order Free Publication in: English Spanish Download PDF 806.08 KB Cocaine is ...

  15. Mind Over Matter: Methamphetamine

    Science.gov (United States)

    ... Term(s): Teachers / NIDA Teaching Guide / Mind Over Matter Teaching Guide and Series / Methamphetamine Mind Over Matter: Methamphetamine (Meth) Print Order Free Publication in: English Spanish Download PDF 739.54 KB Methamphetamine comes ...

  16. BARYONIC DARK MATTER ?

    OpenAIRE

    Rees, M J

    1986-01-01

    In the first two of these lectures, I present the evidence for baryonic dark matter and describe possible forms that it may take. The final lecture discusses formation of baryonic dark matter, and sets the cosmological context.

  17. In vivo characterization of cortical and white matter neuroaxonal pathology in early multiple sclerosis.

    Science.gov (United States)

    Granberg, Tobias; Fan, Qiuyun; Treaba, Constantina Andrada; Ouellette, Russell; Herranz, Elena; Mangeat, Gabriel; Louapre, Céline; Cohen-Adad, Julien; Klawiter, Eric C; Sloane, Jacob A; Mainero, Caterina

    2017-11-01

    Neuroaxonal pathology is a main determinant of disease progression in multiple sclerosis; however, its underlying pathophysiological mechanisms, including its link to inflammatory demyelination and temporal occurrence in the disease course are still unknown. We used ultra-high field (7 T), ultra-high gradient strength diffusion and T1/T2-weighted myelin-sensitive magnetic resonance imaging to characterize microstructural changes in myelin and neuroaxonal integrity in the cortex and white matter in early stage multiple sclerosis, their distribution in lesional and normal-appearing tissue, and their correlations with neurological disability. Twenty-six early stage multiple sclerosis subjects (disease duration ≤5 years) and 24 age-matched healthy controls underwent 7 T T2*-weighted imaging for cortical lesion segmentation and 3 T T1/T2-weighted myelin-sensitive imaging and neurite orientation dispersion and density imaging for assessing microstructural myelin, axonal and dendrite integrity in lesional and normal-appearing tissue of the cortex and the white matter. Conventional mean diffusivity and fractional anisotropy metrics were also assessed for comparison. Cortical lesions were identified in 92% of early multiple sclerosis subjects and they were characterized by lower intracellular volume fraction (P = 0.015 by paired t-test), lower myelin-sensitive contrast (P = 0.030 by related-samples Wilcoxon signed-rank test) and higher mean diffusivity (P = 0.022 by related-samples Wilcoxon signed-rank test) relative to the contralateral normal-appearing cortex. Similar findings were observed in white matter lesions relative to normal-appearing white matter (all P multiple sclerosis subjects had diffusely lower intracellular volume fractions than the white matter in controls (P = 0.029 by unpaired t-test). Cortical thickness did not differ significantly between multiple sclerosis subjects and controls. Higher orientation dispersion in the left primary motor

  18. Nanomedicine a soft matter perspective

    CERN Document Server

    Pan, Dipanjan

    2014-01-01

    This book provides a broad introduction to soft matters for nanomedicinal applications, with a deeper discussion of the individual modalities for molecular imaging. It includes a general introduction to the opportunities provided by this technology in chemistry, materials, biology and nanomedicine. It is designed and written with the perspective that anyone, with or without previous knowledge of nanotechnology, would benefit.

  19. Community Assessment Tool for Public Health Emergencies Including Pandemic Influenza

    Energy Technology Data Exchange (ETDEWEB)

    ORAU' s Oak Ridge Institute for Science Education (HCTT-CHE)

    2011-04-14

    The Community Assessment Tool (CAT) for Public Health Emergencies Including Pandemic Influenza (hereafter referred to as the CAT) was developed as a result of feedback received from several communities. These communities participated in workshops focused on influenza pandemic planning and response. The 2008 through 2011 workshops were sponsored by the Centers for Disease Control and Prevention (CDC). Feedback during those workshops indicated the need for a tool that a community can use to assess its readiness for a disaster - readiness from a total healthcare perspective, not just hospitals, but the whole healthcare system. The CAT intends to do just that - help strengthen existing preparedness plans by allowing the healthcare system and other agencies to work together during an influenza pandemic. It helps reveal each core agency partners (sectors) capabilities and resources, and highlights cases of the same vendors being used for resource supplies (e.g., personal protective equipment [PPE] and oxygen) by the partners (e.g., public health departments, clinics, or hospitals). The CAT also addresses gaps in the community's capabilities or potential shortages in resources. This tool has been reviewed by a variety of key subject matter experts from federal, state, and local agencies and organizations. It also has been piloted with various communities that consist of different population sizes, to include large urban to small rural communities.

  20. Gauged matter coupling in N = 4 supergravity

    NARCIS (Netherlands)

    Roo, M. de; Wagemans, P.

    1985-01-01

    Gauged N = 4 supergravity with an arbitrary number of matter multiplets is constructed from a superconformal starting point. It includes both the SO(4) and SU(4) symmetric N = 4 supergravity theories, and all their gaugings. Noncompact Yang-Mills symmetries may mix the matter and supergravity vector

  1. Dark Matter Effective Theory

    DEFF Research Database (Denmark)

    Del Nobile, Eugenio; Sannino, Francesco

    2012-01-01

    We organize the effective (self)interaction terms for complex scalar dark matter candidates which are either an isosinglet, isodoublet or an isotriplet with respect to the weak interactions. The classification has been performed ordering the operators in inverse powers of the dark matter cutoff...... scale. We assume Lorentz invariance, color and charge neutrality. We also introduce potentially interesting dark matter induced flavor-changing operators. Our general framework allows for model independent investigations of dark matter properties....

  2. Dence Cold Matter

    Directory of Open Access Journals (Sweden)

    Stavinskiy Alexey

    2014-04-01

    Full Text Available Possible way to create dense cold baryonic matter in the laboratory is discussed. The density of this matter is comparable or even larger than the density of neutron star core. The properties of this matter can be controlled by trigger conditions. Experimental program for the study of properties of dense cold matter for light and heavy ion collisions at initial energy range √sNN~2-3GeV is proposed..

  3. Sensibility and Subjectivity: Levinas’ Traumatic Subject

    Directory of Open Access Journals (Sweden)

    Rashmika Pandya

    2011-02-01

    Full Text Available The importance of Levinas’ notions of sensibility and subjectivity are evident in the revision of phenomenological method by current phenomenologists such as Jean-Luc Marion and Michel Henry. The criticisms of key tenants of classical phenomenology, intentionality and reduction, are of a particular note. However, there are problems with Levinas’ characterization of subjectivity as essentially sensible. In “Totality and Infinity” and “Otherwise than Being”, Levinas criticizes and recasts a traditional notion of subjectivity, particularly the notion of the subject as the first and foremost rational subject. The subject in Levinas’ works is characterized more by its sensibility and affectedness than by its capacity to reason or affect its world. Levinas ties rationality to economy and suggests an alternative notion of reason that leads to his analysis of the ethical relation as the face-to-face encounter. The ‘origin’ of the social relation is located not in our capacity to know but rather in a sensibility that is diametrically opposed to the reason understood as economy. I argue that the opposition in Levinas’ thought between reason and sensibility is problematic and essentially leads to a self-conflicted subject. In fact, it would seem that violence characterizes the subject’s self-relation and, thus, is also inscribed at the base of the social relation. Rather than overcoming a problematic tendency to dualistic thought in philosophy Levinas merely reverses traditional hierarchies of reason/emotion, subject/object and self/other. 

  4. Early thermalization of quark-gluon matter initially created in high-energy nucleus-nucleus collisions

    OpenAIRE

    Xu, Xiao-Ming

    2013-01-01

    Elastic parton-parton-parton scattering is briefly reviewed and is included in transport equations of quark-gluon matter. We solve the transport equations and get thermal states from initially produced quark-gluon matter. Both gluon matter and quark matter take early thermalization, but gloun matter has a shorter thermalization time than quark matter.

  5. States of Matter

    Indian Academy of Sciences (India)

    states of matter in school. Are these the only states of matter? What distinguishes different ... can be classified based on color, or electrical properties, or whether they are organic or inorganic, or conductors .... school textbooks continue to preach that there are three states of matter. Thus, I have reduced my problem from ...

  6. Matter and Energy

    CERN Document Server

    Karam, P Andrew

    2011-01-01

    In Matter and Energy, readers will learn about the many forms of energy, the wide variety of particles in nature, and Albert Einstein's world-changing realization of how matter can be changed into pure energy. The book also examines the recent discoveries of dark matter and dark energy and the future of the universe.

  7. Nonthermal Supermassive Dark Matter

    Science.gov (United States)

    Chung, Daniel J. H.; Kolb, Edward W.; Riotto, Antonio

    1999-01-01

    We discuss several cosmological production mechanisms for nonthermal supermassive dark matter and argue that dark matter may he elementary particles of mass much greater than the weak scale. Searches for dark matter should ma be limited to weakly interacting particles with mass of the order of the weak scale, but should extend into the supermassive range as well.

  8. Dissipative dark matter explains rotation curves

    Science.gov (United States)

    Foot, R.

    2015-06-01

    Dissipative dark matter, where dark matter particles interact with a massless (or very light) boson, is studied. Such dark matter can arise in simple hidden sector gauge models, including those featuring an unbroken U (1 )' gauge symmetry, leading to a dark photon. Previous work has shown that such models can not only explain the large scale structure and cosmic microwave background, but potentially also dark matter phenomena on small scales, such as the inferred cored structure of dark matter halos. In this picture, dark matter halos of disk galaxies not only cool via dissipative interactions but are also heated via ordinary supernovae (facilitated by an assumed photon-dark photon kinetic mixing interaction). This interaction between the dark matter halo and ordinary baryons, a very special feature of these types of models, plays a critical role in governing the physical properties of the dark matter halo. Here, we further study the implications of this type of dissipative dark matter for disk galaxies. Building on earlier work, we develop a simple formalism which aims to describe the effects of dissipative dark matter in a fairly model independent way. This formalism is then applied to generic disk galaxies. We also consider specific examples, including NGC 1560 and a sample of dwarf galaxies from the LITTLE THINGS survey. We find that dissipative dark matter, as developed here, does a fairly good job accounting for the rotation curves of the galaxies considered. Not only does dissipative dark matter explain the linear rise of the rotational velocity of dwarf galaxies at small radii, but it can also explain the observed wiggles in rotation curves which are known to be correlated with corresponding features in the disk gas distribution.

  9. The destruction of organic matter

    CERN Document Server

    Gorsuch, T T

    1970-01-01

    International Series of Monographs in Analytical Chemistry, Volume 39: The Destruction of Organic Matter focuses on the identification of trace elements in organic compounds. The monograph first offers information on the processes involved in the determination of trace elements in organic matters, as well as the methods not involving complete destruction of these elements. The text surveys the sources of errors in the processes responsible in pinpointing elements in organic compounds. These processes include sampling, disruption of the samples, manipulation, and measurements. The book

  10. Vestibular loss and balance training cause similar changes in human cerebral white matter fractional anisotropy.

    Directory of Open Access Journals (Sweden)

    Nadine Hummel

    Full Text Available Patients with bilateral vestibular loss suffer from severe balance deficits during normal everyday movements. Ballet dancers, figure skaters, or slackliners, in contrast, are extraordinarily well trained in maintaining balance for the extreme balance situations that they are exposed to. Both training and disease can lead to changes in the diffusion properties of white matter that are related to skill level or disease progression respectively. In this study, we used diffusion tensor imaging (DTI to compare white matter diffusivity between these two study groups and their age- and sex-matched controls. We found that vestibular patients and balance-trained subjects show a reduction of fractional anisotropy in similar white matter tracts, due to a relative increase in radial diffusivity (perpendicular to the main diffusion direction. Reduced fractional anisotropy was not only found in sensory and motor areas, but in a widespread network including long-range connections, limbic and association pathways. The reduced fractional anisotropy did not correlate with any cognitive, disease-related or skill-related factors. The similarity in FA between the two study groups, together with the absence of a relationship between skill or disease factors and white matter changes, suggests a common mechanism for these white matter differences. We propose that both study groups must exert increased effort to meet their respective usual balance requirements. Since balance training has been shown to effectively reduce the symptoms of vestibular failure, the changes in white matter shown here may represent a neuronal mechanism for rehabilitation.

  11. Vestibular loss and balance training cause similar changes in human cerebral white matter fractional anisotropy.

    Science.gov (United States)

    Hummel, Nadine; Hüfner, Katharina; Stephan, Thomas; Linn, Jennifer; Kremmyda, Olympia; Brandt, Thomas; Flanagin, Virginia L

    2014-01-01

    Patients with bilateral vestibular loss suffer from severe balance deficits during normal everyday movements. Ballet dancers, figure skaters, or slackliners, in contrast, are extraordinarily well trained in maintaining balance for the extreme balance situations that they are exposed to. Both training and disease can lead to changes in the diffusion properties of white matter that are related to skill level or disease progression respectively. In this study, we used diffusion tensor imaging (DTI) to compare white matter diffusivity between these two study groups and their age- and sex-matched controls. We found that vestibular patients and balance-trained subjects show a reduction of fractional anisotropy in similar white matter tracts, due to a relative increase in radial diffusivity (perpendicular to the main diffusion direction). Reduced fractional anisotropy was not only found in sensory and motor areas, but in a widespread network including long-range connections, limbic and association pathways. The reduced fractional anisotropy did not correlate with any cognitive, disease-related or skill-related factors. The similarity in FA between the two study groups, together with the absence of a relationship between skill or disease factors and white matter changes, suggests a common mechanism for these white matter differences. We propose that both study groups must exert increased effort to meet their respective usual balance requirements. Since balance training has been shown to effectively reduce the symptoms of vestibular failure, the changes in white matter shown here may represent a neuronal mechanism for rehabilitation.

  12. Detection of white matter lesions in cerebral small vessel disease

    Science.gov (United States)

    Riad, Medhat M.; Platel, Bram; de Leeuw, Frank-Erik; Karssemeijer, Nico

    2013-02-01

    White matter lesions (WML) are diffuse white matter abnormalities commonly found in older subjects and are important indicators of stroke, multiple sclerosis, dementia and other disorders. We present an automated WML detection method and evaluate it on a dataset of small vessel disease (SVD) patients. In early SVD, small WMLs are expected to be of importance for the prediction of disease progression. Commonly used WML segmentation methods tend to ignore small WMLs and are mostly validated on the basis of total lesion load or a Dice coefficient for all detected WMLs. Therefore, in this paper, we present a method that is designed to detect individual lesions, large or small, and we validate the detection performance of our system with FROC (free-response ROC) analysis. For the automated detection, we use supervised classification making use of multimodal voxel based features from different magnetic resonance imaging (MRI) sequences, including intensities, tissue probabilities, voxel locations and distances, neighborhood textures and others. After preprocessing, including co-registration, brain extraction, bias correction, intensity normalization, and nonlinear registration, ventricle segmentation is performed and features are calculated for each brain voxel. A gentle-boost classifier is trained using these features from 50 manually annotated subjects to give each voxel a probability of being a lesion voxel. We perform ROC analysis to illustrate the benefits of using additional features to the commonly used voxel intensities; significantly increasing the area under the curve (Az) from 0.81 to 0.96 (p<0.05). We perform the FROC analysis by testing our classifier on 50 previously unseen subjects and compare the results with manual annotations performed by two experts. Using the first annotator results as our reference, the second annotator performs at a sensitivity of 0.90 with an average of 41 false positives per subject while our automated method reached the same

  13. Levitating dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Kaloper, Nemanja [Department of Physics, University of California, Davis, CA 95616 (United States); Padilla, Antonio, E-mail: kaloper@physics.ucdavis.edu, E-mail: antonio.padilla@nottingham.ac.uk [School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD (United Kingdom)

    2009-10-01

    A sizable fraction of the total energy density of the universe may be in heavy particles with a net dark U(1)' charge comparable to its mass. When the charges have the same sign the cancellation between their gravitational and gauge forces may lead to a mismatch between different measures of masses in the universe. Measuring galactic masses by orbits of normal matter, such as galaxy rotation curves or lensing, will give the total mass, while the flows of dark matter agglomerates may yield smaller values if the gauge repulsion is not accounted for. If distant galaxies which house light beacons like SNe Ia contain such dark particles, the observations of their cosmic recession may mistake the weaker forces for an extra 'antigravity', and infer an effective dark energy equation of state smaller than the real one. In some cases, including that of a cosmological constant, these effects can mimic w < −1. They can also lead to a local variation of galaxy-galaxy forces, yielding a larger 'Hubble Flow' in those regions of space that could be taken for a dynamical dark energy, or superhorizon effects.

  14. Levitating dark matter

    Science.gov (United States)

    Kaloper, Nemanja; Padilla, Antonio

    2009-10-01

    A sizable fraction of the total energy density of the universe may be in heavy particles with a net dark U(1)' charge comparable to its mass. When the charges have the same sign the cancellation between their gravitational and gauge forces may lead to a mismatch between different measures of masses in the universe. Measuring galactic masses by orbits of normal matter, such as galaxy rotation curves or lensing, will give the total mass, while the flows of dark matter agglomerates may yield smaller values if the gauge repulsion is not accounted for. If distant galaxies which house light beacons like SNe Ia contain such dark particles, the observations of their cosmic recession may mistake the weaker forces for an extra `antigravity', and infer an effective dark energy equation of state smaller than the real one. In some cases, including that of a cosmological constant, these effects can mimic w < -1. They can also lead to a local variation of galaxy-galaxy forces, yielding a larger `Hubble Flow' in those regions of space that could be taken for a dynamical dark energy, or superhorizon effects.

  15. Dark Matter in the Universe

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    The question “What is the Universe made of?” is the longest outstanding problem in all of physics. Ordinary atoms only constitute 5% of the total, while the rest is of unknown composition. Already in 1933 Fritz Zwicky observed that the rapid motions of objects within clusters of galaxies were unexplained by the gravitation pull of luminous matter, and he postulated the existence of Dunkle Materie, or dark matter. A variety of dark matter candidates exist, including new fundamental particles already postulated in particle theories: axions and WIMPs (weakly interacting massive particles). Over the past 25 years, there has been a three pronged approach to WIMP detection: creating them at particle accelerators; searched for detection of astrophysical WIMPs scattering off of nuclei in underground detectors; and “indirect detection” of WIMP annihilation products (neutrinos, positrons, or photons). As yet the LHC has only placed bounds rather than finding discovery. For 13 years the DAMA experiment has proc...

  16. Cold dark matter heats up.

    Science.gov (United States)

    Pontzen, Andrew; Governato, Fabio

    2014-02-13

    A principal discovery in modern cosmology is that standard model particles comprise only 5 per cent of the mass-energy budget of the Universe. In the ΛCDM paradigm, the remaining 95 per cent consists of dark energy (Λ) and cold dark matter. ΛCDM is being challenged by its apparent inability to explain the low-density 'cores' of dark matter measured at the centre of galaxies, where centrally concentrated high-density 'cusps' were predicted. But before drawing conclusions, it is necessary to include the effect of gas and stars, historically seen as passive components of galaxies. We now understand that these can inject heat energy into the cold dark matter through a coupling based on rapid gravitational potential fluctuations, explaining the observed low central densities.

  17. Distinguishing medication-free subjects with unipolar disorder from subjects with bipolar disorder : state matters

    NARCIS (Netherlands)

    Rive, Maria M.; Redlich, Ronny; Schmaal, Lianne; Marquand, Andre F.; Dannlowski, Udo; Grotegerd, Dominik; Veltman, Dick J.; Schene, Aart H.; Ruhe, Henricus G.

    2016-01-01

    Objectives: Recent studies have indicated that pattern recognition techniques of functional magnetic resonance imaging (fMRI) data for individual classification may be valuable for distinguishing between major depressive disorder (MDD) and bipolar disorder (BD). Importantly, medication may have

  18. Distinguishing medication-free subjects with unipolar disorder from subjects with bipolar disorder: state matters

    NARCIS (Netherlands)

    Rive, M.M.; Redlich, R.; Schmaal, L.; Marquand, A.F.; Dannlowski, U.; Grotegerd, D.; Veltman, D.J.; Schene, A.H.; Ruhe, H.G.

    2016-01-01

    OBJECTIVES: Recent studies have indicated that pattern recognition techniques of functional magnetic resonance imaging (fMRI) data for individual classification may be valuable for distinguishing between major depressive disorder (MDD) and bipolar disorder (BD). Importantly, medication may have

  19. Impeded Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Kopp, Joachim; Liu, Jia [PRISMA Cluster of Excellence & Mainz Institute for Theoretical Physics,Johannes Gutenberg University,Staudingerweg 7, 55099 Mainz (Germany); Slatyer, Tracy R. [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States); Wang, Xiao-Ping [PRISMA Cluster of Excellence & Mainz Institute for Theoretical Physics,Johannes Gutenberg University,Staudingerweg 7, 55099 Mainz (Germany); Xue, Wei [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States)

    2016-12-12

    We consider dark matter models in which the mass splitting between the dark matter particles and their annihilation products is tiny. Compared to the previously proposed Forbidden Dark Matter scenario, the mass splittings we consider are much smaller, and are allowed to be either positive or negative. To emphasize this modification, we dub our scenario “Impeded Dark Matter”. We demonstrate that Impeded Dark Matter can be easily realized without requiring tuning of model parameters. For negative mass splitting, we demonstrate that the annihilation cross-section for Impeded Dark Matter depends linearly on the dark matter velocity or may even be kinematically forbidden, making this scenario almost insensitive to constraints from the cosmic microwave background and from observations of dwarf galaxies. Accordingly, it may be possible for Impeded Dark Matter to yield observable signals in clusters or the Galactic center, with no corresponding signal in dwarfs. For positive mass splitting, we show that the annihilation cross-section is suppressed by the small mass splitting, which helps light dark matter to survive increasingly stringent constraints from indirect searches. As specific realizations for Impeded Dark Matter, we introduce a model of vector dark matter from a hidden SU(2) sector, and a composite dark matter scenario based on a QCD-like dark sector.

  20. Subjective memory complaints and personality traits in normal elderly subjects.

    Science.gov (United States)

    Hänninen, T; Reinikainen, K J; Helkala, E L; Koivisto, K; Mykkänen, L; Laakso, M; Pyörälä, K; Riekkinen, P J

    1994-01-01

    To evaluate the relationship between objectively measured memory functions and subjective complaints of memory disturbance and whether subjective complaints are affected by some personality traits or affective states. Cross-sectional two-group comparison. The city of Kuopio in Eastern Finland, considered representative of the urban elderly population of Finland. Originally 403 subjects aged 67-78 years from the random sample and then two matched study groups initially including eighteen subjects but only ten in the final analysis. Screening and follow-up examinations of subjects with and without subjective memory complaints: (1) Memory functions: Benton's visual retention test and the paired-associated learning subtest of Wechsler Memory Scale. (2) Memory complaints: Memory Complaint Questionnaire. (3) Personality traits and affective state: Two subscales from Minnesota Multiphasic Personality Inventory and Geriatric Depression Scale. Complaints of memory loss did not correlate with the actual memory performance in the tests. However, those subjects who most emphatically complained of memory disturbance had greater tendencies toward somatic complaining, higher feelings of anxiety about their physical health, and more negative feelings of their own competence and capabilities than those who did not complain of memory deterioration associated with aging. The study suggests that subjective feelings of memory impairment are more closely associated with personality traits than with actual memory performance in normal elderly people.

  1. Collapsed Dark Matter Structures

    Science.gov (United States)

    Buckley, Matthew R.; DiFranzo, Anthony

    2018-02-01

    The distributions of dark matter and baryons in the Universe are known to be very different: The dark matter resides in extended halos, while a significant fraction of the baryons have radiated away much of their initial energy and fallen deep into the potential wells. This difference in morphology leads to the widely held conclusion that dark matter cannot cool and collapse on any scale. We revisit this assumption and show that a simple model where dark matter is charged under a "dark electromagnetism" can allow dark matter to form gravitationally collapsed objects with characteristic mass scales much smaller than that of a Milky-Way-type galaxy. Though the majority of the dark matter in spiral galaxies would remain in the halo, such a model opens the possibility that galaxies and their associated dark matter play host to a significant number of collapsed substructures. The observational signatures of such structures are not well explored but potentially interesting.

  2. Collapsed Dark Matter Structures.

    Science.gov (United States)

    Buckley, Matthew R; DiFranzo, Anthony

    2018-02-02

    The distributions of dark matter and baryons in the Universe are known to be very different: The dark matter resides in extended halos, while a significant fraction of the baryons have radiated away much of their initial energy and fallen deep into the potential wells. This difference in morphology leads to the widely held conclusion that dark matter cannot cool and collapse on any scale. We revisit this assumption and show that a simple model where dark matter is charged under a "dark electromagnetism" can allow dark matter to form gravitationally collapsed objects with characteristic mass scales much smaller than that of a Milky-Way-type galaxy. Though the majority of the dark matter in spiral galaxies would remain in the halo, such a model opens the possibility that galaxies and their associated dark matter play host to a significant number of collapsed substructures. The observational signatures of such structures are not well explored but potentially interesting.

  3. How dark matter came to matter

    Science.gov (United States)

    de Swart, J. G.; Bertone, G.; van Dongen, J.

    2017-03-01

    The history of the dark matter problem can be traced back to at least the 1930s, but it was not until the early 1970s that the issue of 'missing matter' was widely recognized as problematic. In the latter period, previously separate issues involving missing mass were brought together in a single anomaly. We argue that reference to a straightforward accumulation of evidence alone is inadequate to comprehend this episode. Rather, the rise of cosmological research, the accompanying renewed interest in the theory of relativity and changes in the manpower division of astronomy in the 1960s are key to understanding how dark matter came to matter. At the same time, this story may also enlighten us on the methodological dimensions of past practices of physics and cosmology.

  4. 商業方法軟體專利之標的適格性研究 ― 以比較法之研究為中心 The Patentable Subject Matter of Business Method Patents: An Analysis from a Perspective on Comparative Law

    Directory of Open Access Journals (Sweden)

    吉玉成 Yuh-Cherng Jyi

    2004-06-01

    Full Text Available 本文於第2 部分先就商業方法軟體依軟體系統之架構予以定義,以觀察其特殊性,並作為發明專利標的適格分析之基礎。第3 部分則概述商業方法軟體之施以專利保護,對產業與專利審查實務所造成之影響。第4 部分係探討商業方法軟體是否得為發明專利之標的,而依次簡介美國法之規定與實務見解、日本特許法之規定與特許廳之態度、歐洲專利公約與專利局之立場,並由我國專利法之規定,論述絕大多數之商業方法軟體專利,其發明專利之標的適格性乃有欠缺;另就我國智慧財產局所公布之「電腦軟體相關發明專利審查基準」加以探討,及提出個人淺見,並就智慧財產局已核准商業方法軟體專利之實例,予以個案分析。第5 部分則提出個人對商業方法軟體專利之淺見及對我國未來專利保護方向之芻議,以為結 論。 This thesis first in Chapter II defines and identifies business method software under modern computer software architecture so as to form the foundation on which the patentable subject matter of business method software can be further analyzed. In Chapter III follows an overview of how patenting business method software impacts on industry and patent examination practice. Chapter IV analyzes whether business method software qualifies as patentable subject matter from a perspective on comparative legal research in American laws, Japanese laws and the European Patent Convention, and explicates that most of the business method patents granted are unqualified under the interpretation of current ROC Patent Law; this Chapter also reviews the “Examination Guidelines for Computer- Related Software Inventions” promulgated by the Intellectual Property Office from a different perspective and illustrates thereof with a business method patent granted by the Intellectual Property Office. Chapter V concludes this

  5. Organic matter in the universe

    CERN Document Server

    Kwok, Sun

    2012-01-01

    Authored by an experienced writer and a well-known researcher of stellar evolution, interstellar matter and spectroscopy, this unique treatise on the formation and observation of organic compounds in space includes a spectroscopy refresher, as well as links to geological findings and finishes with the outlook for future astronomical facilities and solar system exploration missions. A whole section on laboratory simulations includes the Miller-Urey experiment and the ultraviolet photolysis of ices.

  6. Distributive outcomes matter

    DEFF Research Database (Denmark)

    Svenningsen, Lea Skræp

    This study examines whether people have distributional preferences for the impacts of climate policy when making donations towards such policies. In an online choice experiment, using a real donation mechanism, a representative sample of 95 members of the Danish public are provided 27€ and asked...... to make 16 donation choices among different climate policy options. The climate policies are described in terms of two main outcome variables, including future effects on income in 2100 and present co-benefits from mitigation action. Both outcomes are described for three specific regions of the world...... Adaptation Fund. A random parameter logit model shows that distributional concerns matter for people when they donate to climate policy and that elements of both inequity aversion and general altruism influence the choice of climate policy. The results underscore the importance of considering preferences...

  7. Supersymmetric Dark Matter Candidates

    CERN Document Server

    Ellis, John

    2010-01-01

    After reviewing the theoretical, phenomenological and experimental motivations for supersymmetric extensions of the Standard Model, we recall that supersymmetric relics from the Big Bang are expected in models that conserve R parity. We then discuss possible supersymmetric dark matter candidates, focusing on the lightest neutralino and the gravitino. In the latter case, the next-to-lightest supersymmetric particle is expected to be long-lived, and possible candidates include spartners of the tau lepton, top quark and neutrino. We then discuss the roles of the renormalization-group equations and electroweak symmetry breaking in delimiting the supersymmetric parameter space. We discuss in particular the constrained minimal extension of the Standard Model (CMSSM), in which the supersymmetry-breaking parameters are assumed to be universal at the grand unification scale, presenting predictions from a frequentist analysis of its parameter space. We also discuss astrophysical and cosmological constraints on gravitin...

  8. Dark matter and LHC: Complementarities and limitations arXiv

    CERN Document Server

    Robbins, G.; Arbey, A.; Boudaud, M.

    It is well known that dark matter density measurements, indirect and direct detection experiments, importantly complement the LHC in setting strong constraints on new physics scenarios. Yet, dark matter searches are subject to limitations which need to be considered for realistic analyses. For illustration, we explore the parameter space of the phenomenological MSSM and discuss the interplay of the constraints from dark matter searches and the LHC, and analyse the impact of the astrophysical uncertainties in some detail.

  9. Motives matter: a cultural historical approach to IT mediated subject matter teaching

    DEFF Research Database (Denmark)

    Stenild, Kåre; Iversen, Ole Sejer

    2011-01-01

    The contributors to this collection employ the analytic resources of cultural-historical theory to examine the relationship between childhood and children's development under different societal conditions. In particular they attend to relationships between development, emotions, motives and ident......The contributors to this collection employ the analytic resources of cultural-historical theory to examine the relationship between childhood and children's development under different societal conditions. In particular they attend to relationships between development, emotions, motives...

  10. Relativistic mean-field hadronic models under nuclear matter constraints

    Science.gov (United States)

    Dutra, M.; Lourenço, O.; Avancini, S. S.; Carlson, B. V.; Delfino, A.; Menezes, D. P.; Providência, C.; Typel, S.; Stone, J. R.

    2014-11-01

    Background: The microscopic composition and properties of infinite hadronic matter at a wide range of densities and temperatures have been subjects of intense investigation for decades. The equation of state (EoS) relating pressure, energy density, and temperature at a given particle number density is essential for modeling compact astrophysical objects such as neutron stars, core-collapse supernovae, and related phenomena, including the creation of chemical elements in the universe. The EoS depends not only on the particles present in the matter, but, more importantly, also on the forces acting among them. Because a realistic and quantitative description of infinite hadronic matter and nuclei from first principles in not available at present, a large variety of phenomenological models has been developed in the past several decades, but the scarcity of experimental and observational data does not allow a unique determination of the adjustable parameters. Purpose: It is essential for further development of the field to determine the most realistic parameter sets and to use them consistently. Recently, a set of constraints on properties of nuclear matter was formed and the performance of 240 nonrelativistic Skyrme parametrizations was assessed [M. Dutra et al., Phys. Rev. C 85, 035201 (2012), 10.1103/PhysRevC.85.035201] in describing nuclear matter up to about three times nuclear saturation density. In the present work we examine 263 relativistic-mean-field (RMF) models in a comparable approach. These models have been widely used because of several important aspects not always present in nonrelativistic models, such as intrinsic Lorentz covariance, automatic inclusion of spin, appropriate saturation mechanism for nuclear matter, causality, and, therefore, no problems related to superluminal speed of sound in medium. Method: Three different sets of constraints related to symmetric nuclear matter, pure neutron matter, symmetry energy, and its derivatives were used. The

  11. 46 CFR 289.2 - Vessels included.

    Science.gov (United States)

    2010-10-01

    ... CONSTRUCTION-DIFFERENTIAL SUBSIDY VESSELS, OPERATING-DIFFERENTIAL SUBSIDY VESSELS AND OF VESSELS SOLD OR ADJUSTED UNDER THE MERCHANT SHIP SALES ACT 1946 § 289.2 Vessels included. Vessels subject to the provisions of this part are: (a) All vessels which may in the future be constructed or sold with construction...

  12. Matters of Life and Longing

    DEFF Research Database (Denmark)

    Dalsgaard, Anne Line

    of the ways that phenomenology can be used as a tool of critical social analysis. The book focuses on lived experience and subjective meaning within a life-world dominated by poverty and violence. Through a focus on the basic human need for recognition Dalsgaard describes women’s desire to be valuable...... from simplistic dichotomies of mind/body, history/biography in an effort to grasp human experience in its complexity. “Matters of Life and Longing” is a lucid and accessible work which will be of interest to a wide and varied audience with interest in Latin America, reproductive health, gender studies...

  13. Spatial patterns of whole brain grey and white matter injury in patients with occult spastic diplegic cerebral palsy.

    Science.gov (United States)

    Mu, Xuetao; Nie, Binbin; Wang, Hong; Duan, Shaofeng; Zhang, Zan; Dai, Guanghui; Ma, Qiaozhi; Shan, Baoci; Ma, Lin

    2014-01-01

    Spastic diplegic cerebral palsy (SDCP) is a common type of cerebral palsy (CP), which presents as a group of motor-impairment syndromes. Previous conventional MRI studies have reported abnormal structural changes in SDCP, such as periventricular leucomalacia. However, there are roughly 27.8% SDCP patients presenting normal appearance in conventional MRI, which were considered as occult SDCP. In this study, sixteen patients with occult SDCP and 16 age- and sex-matched healthy control subjects were collected and the data were acquired on a 3T MR system. We applied voxel-based morphometry (VBM) and tract-based spatial statistics (TBSS) analysis to investigate whole brain grey and white matter injury in occult SDCP. By using VBM method, the grey matter volume reduction was revealed in the bilateral basal ganglia regions, thalamus, insula, and left cerebral peduncle, whereas the white matter atrophy was found to be located in the posterior part of corpus callosum and right posterior corona radiata in the occult SDCP patients. By using TBSS, reduced fractional anisotropy (FA) values were detected in multiple white matter regions, including bilateral white matter tracts in prefrontal lobe, temporal lobe, internal and external capsule, corpus callosum, cingulum, thalamus, brainstem and cerebellum. Additionally, several regions of white matter tracts injury were found to be significantly correlated with motor dysfunction. These results collectively revealed the spatial patterns of whole brain grey and white matter injury in occult SDCP.

  14. Dark Matter searches at ATLAS

    CERN Document Server

    Schramm, S; The ATLAS collaboration

    2014-01-01

    Numerous independent astrophysical experiments have observed and measured the influence of the phenomenon named Dark Matter, but its nature is still unknown. If the assumption that Dark Matter is a particle which has a weak coupling to the Standard Model is valid, then collider searches have the ability to search for the production of this new Weakly Interacting Massive Particle (WIMP). Any Dark Matter particles produced in collisions would escape the detector without being observed. Signatures which include an initial-state radiated particle balancing a large amount of Missing Transverse Momentum, known as mono-X topologies, provide a generic means of conducting Dark Matter searches. ATLAS has conducted several mono-X searches, including recoiling jets, photons, W/Z bosons which decay hadronically, and Z bosons which decay leptonically. Searches were carried out with centre of mass energies of both 7 and 8 TeV, and with up to 20/fb of data. No evidence for physics beyond the Standard Model is observed, and t...

  15. Cortical gray matter changes in primary blepharospasm: a voxel-based morphometry study.

    Science.gov (United States)

    Martino, Davide; Di Giorgio, Annabella; D'Ambrosio, Enrico; Popolizio, Teresa; Macerollo, Antonella; Livrea, Paolo; Bertolino, Alessandro; Defazio, Giovanni

    2011-08-15

    Previous voxel-based morphometry studies of patients with primary blepharospasm documented gray matter volumetric differences of the striatum, cerebellum, thalamus, and parietal lobe areas. However, these results were inconsistent across studies, which recruited relatively small samples and did not always provide detailed clinical information on patients with blepharospasm. The objective of this study was to analyze whole-brain gray matter volume in a larger sample of patients with blepharospasm and to expand on previous works by evaluating whether clinical features of blepharospasm correlate to whole-brain gray matter changes. Voxel-based morphometry was performed on 25 patients with primary adult-onset blepharospasm and 24 healthy subjects (controls) matched for age, sex, and handedness. Clinical data were collected through a standardized interview. Severity of blepharospasm was measured using the Jankovic Rating Scale. Patients with blepharospasm had greater gray matter volume than controls in the right middle frontal gyrus, whereas patients with blepharospasm had smaller gray matter volume than controls in the left postcentral gyrus and left superior temporal gyrus. Spearman correlation analysis with Bonferroni correction failed to show significant correlations between gray matter volume and the explored clinical variables, comprising age at onset, disease duration, blepharospasm severity, presence of an effective geste antagoniste, and dose and duration of botulinum toxin treatment. Patients with blepharospasm exhibited gray matter volume differences exclusively in cortical regions highly relevant to sensory processing and cognitive modulation of motor behavior. Gray matter changes in the primary sensory cortex may represent a common trait of primary dystonias, including blepharospasm. Copyright © 2011 Movement Disorder Society.

  16. Increased number of white matter lesions in patients with familial cerebral cavernous malformations.

    Science.gov (United States)

    Golden, M J; Morrison, L A; Kim, H; Hart, B L

    2015-05-01

    Familial cerebral cavernous malformations, an autosomal dominant disorder, result in excess morbidity and mortality in affected patients. The disorder is most prevalent in the Southwest United States, where the affected families are most often carriers of the CCM1-KRIT1 Common Hispanic Mutation. The brain and spinal cord parenchyma in these individuals is usually affected by multiple cavernous malformations. Previous studies have shown abnormalities of endothelial cell junctions and the blood-brain barrier in cerebral cavernous malformations. Endothelial cell abnormalities have also been described in pathologic studies of white matter hyperintensities. We compared the prevalence of white matter hyperintensities in a population with known familial cerebral cavernous malformations. We examined 191 subjects with familial cerebral cavernous malformations who were enrolled into an institutional review board-approved study. All carry the same Common Hispanic Mutation in the CCM1 gene. Each subject underwent 3T MR imaging, including gradient recalled-echo, SWI, and FLAIR sequences. The number of cavernous malformations and the number of nonhemorrhagic white matter hyperintensities were counted. Subjects older than 60 years of age were excluded due to the high prevalence of white matter lesions in this population, and children younger than 6 were excluded due to potential sedation requirements. Logistic regression analysis was performed to determine the prevalence of abnormal white matter hyperintensities in those with familial cerebral cavernous malformations compared with healthy controls or those with sporadic cerebral cavernous malformation within the familial cerebral cavernous malformations group; it was also performed to evaluate the associations between abnormal white matter hyperintensities and age, sex, headaches, thyroid disease, diabetes, hypertension, hyperlipidemia, seizure history, or modified Rankin Scale score. Familial CCM1 carriers have a higher

  17. Diesel Particulate Matter Polygons, Arizona, 2005, NATA

    Data.gov (United States)

    U.S. Environmental Protection Agency — The national-scale assessment includes 177 air pollutants (a subset of the air toxics on the Clean Air Act's list of 187 air toxics plus diesel particulate matter...

  18. Diesel Particulate Matter Polygons, Hawaii, 2005, NATA

    Data.gov (United States)

    U.S. Environmental Protection Agency — The national-scale assessment includes 177 air pollutants (a subset of the air toxics on the Clean Air Act's list of 187 air toxics plus diesel particulate matter...

  19. Diesel Particulate Matter Polygons, Nevada, 2005, NATA

    Data.gov (United States)

    U.S. Environmental Protection Agency — The national-scale assessment includes 177 air pollutants (a subset of the air toxics on the Clean Air Act's list of 187 air toxics plus diesel particulate matter...

  20. Diesel Particulate Matter Polygons, California, 2005, NATA

    Data.gov (United States)

    U.S. Environmental Protection Agency — The national-scale assessment includes 177 air pollutants (a subset of the air toxics on the Clean Air Act's list of 187 air toxics plus diesel particulate matter...

  1. Silage quality, dry matter intake and digestibility by West African ...

    African Journals Online (AJOL)

    Grass mixtures were subjected to silage for 42 days. Quality and chemical composition of the silage was assessed. Silage was also fed to WAD sheep to determine the dry matter intake (DMI) and dry matter digestibility (DMD). Crude protein for 4WGG was 17.5% higher than that of 12WGG. Silage colour was normal except ...

  2. Understanding Physical Educators' Perceptions of Mattering Questionnaire--Physical Education

    Science.gov (United States)

    Richards, K. Andrew R.; Gaudreault, Karen Lux; Woods, Amelia Mays

    2017-01-01

    Previous research has illustrated that physical educators feel their subject is valued less than others in the context of schools. However, to date, no instruments have been developed to measure physical education teachers' perceptions of mattering. This study sought to propose and validate the Perceived Mattering Questionnaire--Physical Education…

  3. Atopic asthmatic subjects but not atopic subjects without ...

    Science.gov (United States)

    BACKGROUND: Asthma is a known risk factor for acute ozone-associated respiratory disease. Ozone causes an immediate decrease in lung function and increased airway inflammation. The role of atopy and asthma in modulation of ozone-induced inflammation has not been determined. OBJECTIVE: We sought to determine whether atopic status modulates ozone response phenotypes in human subjects. METHODS: Fifty volunteers (25 healthy volunteers, 14 atopic nonasthmatic subjects, and 11 atopic asthmatic subjects not requiring maintenance therapy) underwent a 0.4-ppm ozone exposure protocol. Ozone response was determined based on changes in lung function and induced sputum composition, including airway inflammatory cell concentration, cell-surface markers, and cytokine and hyaluronic acid concentrations. RESULTS: All cohorts experienced similar decreases in lung function after ozone. Atopic and atopic asthmatic subjects had increased sputum neutrophil numbers and IL-8 levels after ozone exposure; values did not significantly change in healthy volunteers. After ozone exposure, atopic asthmatic subjects had significantly increased sputum IL-6 and IL-1beta levels and airway macrophage Toll-like receptor 4, Fc(epsilon)RI, and CD23 expression; values in healthy volunteers and atopic nonasthmatic subjects showed no significant change. Atopic asthmatic subjects had significantly decreased IL-10 levels at baseline compared with healthy volunteers; IL-10 levels did not significa

  4. Codecaying Dark Matter.

    Science.gov (United States)

    Dror, Jeff Asaf; Kuflik, Eric; Ng, Wee Hao

    2016-11-18

    We propose a new mechanism for thermal dark matter freeze-out, called codecaying dark matter. Multicomponent dark sectors with degenerate particles and out-of-equilibrium decays can codecay to obtain the observed relic density. The dark matter density is exponentially depleted through the decay of nearly degenerate particles rather than from Boltzmann suppression. The relic abundance is set by the dark matter annihilation cross section, which is predicted to be boosted, and the decay rate of the dark sector particles. The mechanism is viable in a broad range of dark matter parameter space, with a robust prediction of an enhanced indirect detection signal. Finally, we present a simple model that realizes codecaying dark matter.

  5. White matter hyperintensities and changes in white matter integrity in patients with Alzheimer's disease

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Liya; Mao, Hui [Emory University School of Medicine, Department of Radiology, Atlanta, GA (United States); Emory University School of Medicine, Center for Systems Imaging, Atlanta, GA (United States); Goldstein, Felicia C.; Levey, Allan I.; Lah, James J. [Emory University School of Medicine, Department of Neurology, Atlanta, GA (United States); Meltzer, Carolyn C. [Emory University School of Medicine, Department of Radiology, Atlanta, GA (United States); Emory University School of Medicine, Center for Systems Imaging, Atlanta, GA (United States); Emory University School of Medicine, Department of Neurology, Atlanta, GA (United States); Emory University School of Medicine, Department of Psychiatry and Behavior Sciences, Atlanta, GA (United States); Holder, Chad A. [Emory University School of Medicine, Department of Radiology, Atlanta, GA (United States)

    2011-05-15

    White matter hyperintensities (WMHs) are a risk factor for Alzheimer's disease (AD). This study investigated the relationship between WMHs and white matter changes in AD using diffusion tensor imaging (DTI) and the sensitivity of each DTI index in distinguishing AD with WMHs. Forty-four subjects with WMHs were included. Subjects were classified into three groups based on the Scheltens rating scale: 15 AD patients with mild WMHs, 12 AD patients with severe WMHs, and 17 controls with mild WMHs. Fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (D{sub R}), and axial diffusivity (D{sub A}) were analyzed using the region of interest and tract-based spatial statistics methods. Sensitivity and specificity of DTI indices in distinguishing AD groups from the controls were evaluated. AD patients with mild WMHs exhibited differences from control subjects in most DTI indices in the medial temporal and frontal areas; however, differences in DTI indices from AD patients with mild WMHs and AD patients with severe WMHs were found in the parietal and occipital areas. FA and D{sub R} were more sensitive measurements than MD and D{sub A} in differentiating AD patients from controls, while MD was a more sensitive measurement in distinguishing AD patients with severe WMHs from those with mild WMHs. WMHs may contribute to the white matter changes in AD brains, specifically in temporal and frontal areas. Changes in parietal and occipital lobes may be related to the severity of WMHs. D{sub R} may serve as an imaging marker of myelin deficits associated with AD. (orig.)

  6. Dark Matter Indirect Signatures

    OpenAIRE

    Lavalle, Julien; Salati, Pierre

    2012-01-01

    The astronomical dark matter could be made of weakly interacting and massive particles. If so, these species would be abundant inside the Milky Way, where they would continuously annihilate and produce cosmic rays. Those annihilation products are potentially detectable at the Earth, and could provide indirect clues for the presence of dark matter species within the Galaxy. We will review here the various cosmic radiations which the dark matter can produce. We will examine how they propagate t...

  7. Clumpy cold dark matter

    Science.gov (United States)

    Silk, Joseph; Stebbins, Albert

    1993-01-01

    A study is conducted of cold dark matter (CDM) models in which clumpiness will inhere, using cosmic strings and textures suited to galaxy formation. CDM clumps of 10 million solar mass/cu pc density are generated at about z(eq) redshift, with a sizable fraction surviving. Observable implications encompass dark matter cores in globular clusters and in galactic nuclei. Results from terrestrial dark matter detection experiments may be affected by clumpiness in the Galactic halo.

  8. Soft matter physics

    CERN Document Server

    Doi, Masao

    2013-01-01

    Soft matter (polymers, colloids, surfactants and liquid crystals) are an important class of materials in modern technology. They also form the basis of many future technologies, for example in medical and environmental applications. Soft matter shows complex behaviour between fluids and solids, and used to be a synonym of complex materials. Due to the developments of the past two decades, soft condensed matter can now be discussed on the same sound physical basis as solid condensedmatter. The purpose of this book is to provide an overview of soft matter for undergraduate and graduate students

  9. Searches for dark matter

    CERN Document Server

    Feinstein, Fabrice

    2000-01-01

    The fact that the mass of the visible stars could not account for the gravitational cohesion of the galaxies was the first sign of non-visible (i.e. dark) matter in the Universe. Since then, many observational evidences tell us that most of the matter is indeed dark. The nature of this dark matter is still unknown. There are good reasons to think that most of it is not composed of normal matter. These lectures will review the experimental methods, which have been developed to unravel this mystery and will compare their results with theoretical predictions.

  10. An introduction to particle dark matter

    CERN Document Server

    Profumo, Stefano

    2017-01-01

    What is the dark matter that fills the Universe and binds together galaxies? How was it produced? What are its interactions and particle properties?The paradigm of dark matter is one of the key developments at the interface of cosmology and elementary particle physics. It is also one of the foundations of the standard cosmological model. This book presents the state of the art in building and testing particle models for dark matter. Each chapter gives an analysis of questions, research directions, and methods within the field. More than 200 problems are included to challenge and stimulate the reader's knowledge and provide guidance in the practical implementation of the numerous 'tools of the trade' presented. Appendices summarize the basics of cosmology and particle physics needed for any quantitative understanding of particle models for dark matter.This interdisciplinary textbook is essential reading for anyone interested in the microscopic nature of dark matter as it manifests itself in particle physics ex...

  11. Concepts of matter in science education

    CERN Document Server

    Sevian, Hannah

    2013-01-01

    Bringing together a wide collection of ideas, reviews, analyses and new research on particulate and structural concepts of matter, Concepts of Matter in Science Education informs practice from pre-school through graduate school learning and teaching and aims to inspire progress in science education. The expert contributors offer a range of reviews and critical analyses of related literature and in-depth analysis of specific issues, as well as new research. Among the themes covered are learning progressions for teaching a particle model of matter, the mental models of both students and teachers of the particulate nature of matter, educational technology, chemical reactions and chemical phenomena, chemical structure and bonding, quantum chemistry and the history and philosophy of science relating to the particulate nature of matter. The book will benefit a wide audience including classroom practitioners and student teachers at every educational level, teacher educators and researchers in science education.

  12. Traumatic white matter injury and toxic leukoencephalopathies.

    Science.gov (United States)

    Al-Hasani, Omer Hussain; Smith, Colin

    2011-09-01

    White matter injury may be secondary to a range of neurodegenerative disorders, such as the common dementing disorders of the elderly, or may be a consequence of specific white matter disorders, such as multiple sclerosis and the rare leukodystrophies. This article will focus on two relatively common primary groups of disorders of the white matter, traumatic white matter injury and toxic leukoencephalopathies. Traumatic axonal injury may be focal or diffuse, and is associated with a clinical spectrum ranging from concussion through to coma and death. The molecular mechanisms underlying axonal degeneration secondary to traumatic axonal degeneration are being elucidated and may give an insight into potential therapeutic targets. Toxic leukoencephalopathy may be secondary to exposure to a wide range of compounds, including chemotherapeutic drugs. These toxins may produce white matter injury through a range of mechanisms, and the potential toxic effects of compounds need to be considered when assessing a patient with a nonspecific leukoencephalopathy.

  13. A subjective scheduler for subjective dedicated networks

    Science.gov (United States)

    Suherman; Fakhrizal, Said Reza; Al-Akaidi, Marwan

    2017-09-01

    Multiple access technique is one of important techniques within medium access layer in TCP/IP protocol stack. Each network technology implements the selected access method. Priority can be implemented in those methods to differentiate services. Some internet networks are dedicated for specific purpose. Education browsing or tutorial video accesses are preferred in a library hotspot, while entertainment and sport contents could be subjects of limitation. Current solution may use IP address filter or access list. This paper proposes subjective properties of users or applications are used for priority determination in multiple access techniques. The NS-2 simulator is employed to evaluate the method. A video surveillance network using WiMAX is chosen as the object. Subjective priority is implemented on WiMAX scheduler based on traffic properties. Three different traffic sources from monitoring video: palace, park, and market are evaluated. The proposed subjective scheduler prioritizes palace monitoring video that results better quality, xx dB than the later monitoring spots.

  14. [Age-related white matter lesions (leukoaraiosis): an update].

    Science.gov (United States)

    Miki, Yukio; Sakamoto, Shinichi

    2013-07-01

    Leukoaraiosis (age-related white matter hyperintensities) is the most frequently seen lesion on brain magnetic resonance (MR) images. This lesion is a subject of much current interest, because a number of multicenter studies have revealed that it is associated with various disturbances and poor prognoses. Leukoaraiosis corresponds to various pathologies, including demyelination, apoptosis, edema, dilated perivascular spaces, axonal damage, gliosis, and infarcts. Also noted in leukoaraiosis are changes in small vessels, such as fibrohyalinosis and venous collagenosis. The main cause of leukoaraiosis is thought to be chronic ischemia; other causes include edema and breakdown of the blood-brain barrier. Major risk factors for leukoaraiosis are age and hypertension. Disturbances that are related to leukoaraiosis include stroke, dementia, cognitive impairment, gait disturbance, fall, and depression. Leukoaraiosis is also a risk factor for death. Technologies, such as automatic volumetry, tissue segmentation, diffusion tensor imaging, magnetization tensor imaging, diffusion kurtosis imaging, and ultra-high field MR imaging may provide further insights into leukoaraiosis.

  15. Ratcheting Up The Search for Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    McDermott, Samuel Dylan [Univ. of Michigan, Ann Arbor, MI (United States)

    2014-01-01

    The last several years have included remarkable advances in two of the primary areas of fundamental particle physics: the search for dark matter and the discovery of the Higgs boson. This dissertation will highlight some contributions made on the forefront of these exciting fields. Although the circumstantial evidence supporting the dark matter hypothesis is now almost undeniably significant, indisputable direct proof is still lacking. As the direct searches for dark matter continue, we can maximize our prospects of discovery by using theoretical techniques complementary to the observational searches to rule out additional, otherwise accessible parameter space. In this dissertation, I report bounds on a wide range of dark matter theories. The models considered here cover the spectrum from the canonical case of self-conjugate dark matter with weak-scale interactions, to electrically charged dark matter, to non-annihilating, non-fermionic dark matter. These bounds are obtained from considerations of astrophysical and cosmological data, including, respectively: diffuse gamma ray photon observations; structure formation considerations, along with an explication of the novel local dark matter structure due to galactic astrophysics; and the existence of old pulsars in dark-matter-rich environments. I also consider the prospects for a model of neutrino dark matter which has been motivated by a wide set of seemingly contradictory experimental results. In addition, I include a study that provides the tools to begin solving the speculative ``inverse'' problem of extracting dark matter properties solely from hypothetical nuclear energy spectra, which we may face if dark matter is discovered with multiple direct detection experiments. In contrast to the null searches for dark matter, we have the example of the recent discovery of the Higgs boson. The Higgs boson is the first fundamental scalar particle ever observed, and precision measurements of the production and

  16. EDITORIAL: Focus on Dark Matter and Particle Physics

    Science.gov (United States)

    Aprile, Elena; Profumo, Stefano

    2009-10-01

    The quest for the nature of dark matter has reached a historical point in time, with several different and complementary experiments on the verge of conclusively exploring large portions of the parameter space of the most theoretically compelling particle dark matter models. This focus issue on dark matter and particle physics brings together a broad selection of invited articles from the leading experimental and theoretical groups in the field. The leitmotif of the collection is the need for a multi-faceted search strategy that includes complementary experimental and theoretical techniques with the common goal of a sound understanding of the fundamental particle physical nature of dark matter. These include theoretical modelling, high-energy colliders and direct and indirect searches. We are confident that the works collected here present the state of the art of this rapidly changing field and will be of interest to both experts in the topic of dark matter as well as to those new to this exciting field. Focus on Dark Matter and Particle Physics Contents DARK MATTER AND ASTROPHYSICS Scintillator-based detectors for dark matter searches I S K Kim, H J Kim and Y D Kim Cosmology: small-scale issues Joel R Primack Big Bang nucleosynthesis and particle dark matter Karsten Jedamzik and Maxim Pospelov Particle models and the small-scale structure of dark matter Torsten Bringmann DARK MATTER AND COLLIDERS Dark matter in the MSSM R C Cotta, J S Gainer, J L Hewett and T G Rizzo The role of an e+e- linear collider in the study of cosmic dark matter M Battaglia Collider, direct and indirect detection of supersymmetric dark matter Howard Baer, Eun-Kyung Park and Xerxes Tata INDIRECT PARTICLE DARK MATTER SEARCHES:EXPERIMENTS PAMELA and indirect dark matter searches M Boezio et al An indirect search for dark matter using antideuterons: the GAPS experiment C J Hailey Perspectives for indirect dark matter search with AMS-2 using cosmic-ray electrons and positrons B Beischer, P von

  17. Flavored dark matter beyond Minimal Flavor Violation

    CERN Document Server

    Agrawal, Prateek; Gemmler, Katrin

    2014-10-13

    We study the interplay of flavor and dark matter phenomenology for models of flavored dark matter interacting with quarks. We allow an arbitrary flavor structure in the coupling of dark matter with quarks. This coupling is assumed to be the only new source of violation of the Standard Model flavor symmetry extended by a $U(3)_\\chi$ associated with the dark matter. We call this ansatz Dark Minimal Flavor Violation (DMFV) and highlight its various implications, including an unbroken discrete symmetry that can stabilize the dark matter. As an illustration we study a Dirac fermionic dark matter $\\chi$ which transforms as triplet under $U(3)_\\chi$, and is a singlet under the Standard Model. The dark matter couples to right-handed down-type quarks via a colored scalar mediator $\\phi$ with a coupling $\\lambda$. We identify a number of "flavor-safe" scenarios for the structure of $\\lambda$ which are beyond Minimal Flavor Violation. For dark matter and collider phenomenology we focus on the well-motivated case of $b$-...

  18. Do Social Networks Improve Chinese Adults' Subjective Well-being?

    Science.gov (United States)

    Lei, Xiaoyan; Shen, Yan; Smith, James P; Zhou, Guangsu

    2015-12-01

    This paper studies relationships between social networks, health and subjective well-being (SWB) using nationally representative data of the Chinese Population-the Chinese Family Panel Studies (CFPS). Our data contain SWB indicators in two widely used variants-happiness and life-satisfaction. Social network variables used include kinship relationships measured by marital status, family size, and having a genealogy; ties with friends/relatives/neighbors measured by holiday visitation, frequency of contacts, and whether and value gifts given and received; total number and time spent in social activities, and engagement in organizations including the communist party, religious groups, and other types. We find that giving and receiving gifts has a larger impact on SWB than either just giving or receiving them. Similarly the number of friends is more important than number of relatives, and marriage is associated with higher levels of SWB. Time spent in social activities and varieties of activities both matter for SWB but varieties matter more. Participation in organizations is associated with higher SWB across such diverse groups as being a member of the communist party or a religious organization. China represents an interesting test since it is simultaneously a traditional society with long-established norms about appropriate social networks and a rapidly changing society due to substantial economic and demographic changes. We find that it is better to both give and receive, to engage in more types of social activities, and that participation in groups all improve well-being of Chinese people.

  19. Disability, participation, and subjective wellbeing among older couples.

    Science.gov (United States)

    Freedman, Vicki A; Stafford, Frank; Schwarz, Norbert; Conrad, Frederick; Cornman, Jennifer C

    2012-02-01

    This paper investigates the link between disability and subjective wellbeing, using data from the 2009 Disability and Use of Time supplement to the Panel Study of Income Dynamics, the longest running national panel study in the United States. Disability is construed broadly to include both the presence of any physical, cognitive, or sensory impairment or activity limitation and also the severity of underlying impairments. Subjective wellbeing is measured using two distinct approaches: reports of life satisfaction and of moment-to-moment wellbeing-both positive and negative-on the previous day. The latter, collected through 24-h time diaries, also offers for the first time the ability to explore the role of participation in particular kinds of activities linking disability to subjective wellbeing. The analytic sample included married persons ages 60 and older and their spouses (n = 751 married individuals) who completed 1498 diaries. Several new findings emerged: no matter what the measure of wellbeing, older married adults with disability report worse subjective wellbeing than those without, and neither different demographic and socioeconomic profiles nor differences in participation fully account for these disparities. Influences of disability on global life satisfaction and episodic reports of happiness were relatively small and of comparable size. However, notably sizeable differences were identified in the cumulative number of pleasant minutes experienced yesterday by disability status - on the order of 71 fewer minutes on average for those with a disability of average severity. Differences appear to be more strongly linked to somatic symptoms of pain and feeling tired than to differential intensity of experiencing happiness, sadness, frustration, or worry. We also found limited support for the notion that participation partially mediates the relationship between disability and global, but not episodic, subjective wellbeing. Copyright © 2011 Elsevier Ltd. All

  20. Subjective wellbeing and income: Empirical patterns in the rural developing world

    Science.gov (United States)

    Reyes-García, Victoria; Babigumira, Ronnie; Pyhälä, Aili; Wunder, Sven; Zorondo-Rodríguez, Francisco; Angelsen, Arild

    2016-01-01

    A commonality in the economics of happiness literature is that absolute income matters more for the subjective wellbeing of people at low income levels. In this article, we use a large sample of people in rural areas of developing countries with relatively low income levels to test whether subjective wellbeing an increasing function of absolute income in our sample, and to analyze the existence of adaptation and social comparison effects on subjective wellbeing. Our sample includes 6973 rural households in 23 countries throughout Asia, Africa, and Latin America. The average total income per adult equivalent in our sample was US$1555, whereas levels of subjective wellbeing resembled levels found in previous research using cross-country data. We find that, despite low levels of absolute income, levels of subjective wellbeing of our respondents resemble levels found in previous research using cross-country data. We also find remarkable similarities in many of the determinants of subjective wellbeing previously tested. Our data show that absolute income covariates with subjective wellbeing, but -as for richer samples- the magnitude of the association is lower once we control for adaptation and social comparison. Finally, our results suggest that social comparison has a stronger effect than adaptation in explaining the subjective wellbeing of our sample. Our findings highlight the importance of adaptation and social comparison even at low levels of absolute income. PMID:27642259

  1. Association between exercise habits and subcortical gray matter volumes in healthy elderly people: A population-based study in Japan

    Directory of Open Access Journals (Sweden)

    Mikie Yamamoto

    2017-06-01

    Conclusion: Subjects with exercise habits show larger subcortical gray matter volumes than subjects without exercise habits in community-dwelling elderly subjects in Japan. Specifically, the volume of the nucleus accumbens correlates with both exercise habits and cognitive preservation.

  2. White matter integrity, creativity, and psychopathology: disentangling constructs with diffusion tensor imaging.

    Directory of Open Access Journals (Sweden)

    Rex E Jung

    Full Text Available That creativity and psychopathology are somehow linked remains a popular but controversial idea in neuroscience research. Brain regions implicated in both psychosis-proneness and creative cognition include frontal projection zones and association fibers. In normal subjects, we have previously demonstrated that a composite measure of divergent thinking (DT ability exhibited significant inverse relationships in frontal lobe areas with both cortical thickness and metabolite concentration of N-acetyl-aspartate (NAA. These findings support the idea that creativity may reside upon a continuum with psychopathology. Here we examine whether white matter integrity, assessed by Fractional Anisotropy (FA, is related to two measures of creativity (Divergent Thinking and Openness to Experience. Based on previous findings, we hypothesize inverse correlations within fronto-striatal circuits. Seventy-two healthy, young adult (18-29 years subjects were scanned on a 3 Tesla scanner with Diffusion Tensor Imaging. DT measures were scored by four raters (alpha = .81 using the Consensual Assessment Technique, from which a composite creativity index (CCI was derived. We found that the CCI was significantly inversely related to FA within the left inferior frontal white matter (t = 5.36, p = .01, and Openness was inversely related to FA within the right inferior frontal white matter (t = 4.61, p = .04. These findings demonstrate an apparent overlap in specific white matter architecture underlying the normal variance of divergent thinking, openness, and psychotic-spectrum traits, consistent with the idea of a continuum.

  3. White matter integrity, creativity, and psychopathology: disentangling constructs with diffusion tensor imaging.

    Science.gov (United States)

    Jung, Rex E; Grazioplene, Rachael; Caprihan, Arvind; Chavez, Robert S; Haier, Richard J

    2010-03-22

    That creativity and psychopathology are somehow linked remains a popular but controversial idea in neuroscience research. Brain regions implicated in both psychosis-proneness and creative cognition include frontal projection zones and association fibers. In normal subjects, we have previously demonstrated that a composite measure of divergent thinking (DT) ability exhibited significant inverse relationships in frontal lobe areas with both cortical thickness and metabolite concentration of N-acetyl-aspartate (NAA). These findings support the idea that creativity may reside upon a continuum with psychopathology. Here we examine whether white matter integrity, assessed by Fractional Anisotropy (FA), is related to two measures of creativity (Divergent Thinking and Openness to Experience). Based on previous findings, we hypothesize inverse correlations within fronto-striatal circuits. Seventy-two healthy, young adult (18-29 years) subjects were scanned on a 3 Tesla scanner with Diffusion Tensor Imaging. DT measures were scored by four raters (alpha = .81) using the Consensual Assessment Technique, from which a composite creativity index (CCI) was derived. We found that the CCI was significantly inversely related to FA within the left inferior frontal white matter (t = 5.36, p = .01), and Openness was inversely related to FA within the right inferior frontal white matter (t = 4.61, p = .04). These findings demonstrate an apparent overlap in specific white matter architecture underlying the normal variance of divergent thinking, openness, and psychotic-spectrum traits, consistent with the idea of a continuum.

  4. Asymptotically Safe Dark Matter

    DEFF Research Database (Denmark)

    Sannino, Francesco; Shoemaker, Ian M.

    2015-01-01

    We introduce a new paradigm for dark matter (DM) interactions in which the interaction strength is asymptotically safe. In models of this type, the coupling strength is small at low energies but increases at higher energies, and asymptotically approaches a finite constant value. The resulting...... searches are the primary ways to constrain or discover asymptotically safe dark matter....

  5. Dark Matter Day

    CERN Document Server

    CERN. Geneva

    2017-01-01

    Wessel Valkenburg, Research Fellow at the Theory Department at CERN will explain the how and why research is carried out on dark matter. The event will be in English with simultaneous interpretation into French. Dark Matter Day falls on Hallow...

  6. CORRELATION BETWEEN PARTICULATE MATTER ...

    African Journals Online (AJOL)

    BIG TIMMY

    2017-03-21

    Mar 21, 2017 ... Measurement of atmospheric particulate matter was carried out with a view to establish the potential influence of meteorological parameters such as wind speed, wind direction, air temperature, rainfall, relative humidity and global radiation on the mass concentration. Particulate matter (PM) in two size ...

  7. Dark matter and cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Schramm, D.N.

    1992-03-01

    The cosmological dark matter problem is reviewed. The Big Bang Nucleosynthesis constraints on the baryon density are compared with the densities implied by visible matter, dark halos, dynamics of clusters, gravitational lenses, large-scale velocity flows, and the {Omega} = 1 flatness/inflation argument. It is shown that (1) the majority of baryons are dark; and (2) non-baryonic dark matter is probably required on large scales. It is also noted that halo dark matter could be either baryonic or non-baryonic. Descrimination between cold'' and hot'' non-baryonic candidates is shown to depend on the assumed seeds'' that stimulate structure formation. Gaussian density fluctuations, such as those induced by quantum fluctuations, favor cold dark matter, whereas topological defects such as strings, textures or domain walls may work equally or better with hot dark matter. A possible connection between cold dark matter, globular cluster ages and the Hubble constant is mentioned. Recent large-scale structure measurements, coupled with microwave anisotropy limits, are shown to raise some questions for the previously favored density fluctuation picture. Accelerator and underground limits on dark matter candidates are also reviewed.

  8. Dark matter and cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Schramm, D.N.

    1992-03-01

    The cosmological dark matter problem is reviewed. The Big Bang Nucleosynthesis constraints on the baryon density are compared with the densities implied by visible matter, dark halos, dynamics of clusters, gravitational lenses, large-scale velocity flows, and the {Omega} = 1 flatness/inflation argument. It is shown that (1) the majority of baryons are dark; and (2) non-baryonic dark matter is probably required on large scales. It is also noted that halo dark matter could be either baryonic or non-baryonic. Descrimination between ``cold`` and ``hot`` non-baryonic candidates is shown to depend on the assumed ``seeds`` that stimulate structure formation. Gaussian density fluctuations, such as those induced by quantum fluctuations, favor cold dark matter, whereas topological defects such as strings, textures or domain walls may work equally or better with hot dark matter. A possible connection between cold dark matter, globular cluster ages and the Hubble constant is mentioned. Recent large-scale structure measurements, coupled with microwave anisotropy limits, are shown to raise some questions for the previously favored density fluctuation picture. Accelerator and underground limits on dark matter candidates are also reviewed.

  9. Enabling forbidden dark matter

    Science.gov (United States)

    Cline, James M.; Liu, Hongwan; Slatyer, Tracy R.; Xue, Wei

    2017-10-01

    The thermal relic density of dark matter is conventionally set by two-body annihilations. We point out that in many simple models, 3 →2 annihilations can play an important role in determining the relic density over a broad range of model parameters. This occurs when the two-body annihilation is kinematically forbidden, but the 3 →2 process is allowed; we call this scenario not-forbidden dark matter. We illustrate this mechanism for a vector-portal dark matter model, showing that for a dark matter mass of mχ˜MeV -10 GeV , 3 →2 processes not only lead to the observed relic density, but also imply a self-interaction cross section that can solve the cusp/core problem. This can be accomplished while remaining consistent with stringent CMB constraints on light dark matter, and can potentially be discovered at future direct detection experiments.

  10. Imperfect Dark Matter

    CERN Document Server

    Mirzagholi, Leila

    2014-01-01

    We consider cosmology of the recently introduced mimetic matter with higher derivatives (HD). Without HD this system describes irrotational dust - Dark Matter (DM) as we see it on cosmologically large scales. DM particles correspond to the shift-charges - Noether charges of the shifts in the field space. Higher derivative corrections usually describe a deviation from the thermodynamical equilibrium in the relativistic hydrodynamics. Thus we show that mimetic matter with HD corresponds to an imperfect DM which: i) renormalises the Newton's constant in the Friedmann equations, ii) has zero pressure when there is no extra matter in the universe, iii) survives the inflationary expansion which puts the system on a dynamical attractor with a vanishing shift-charge, iv) perfectly tracks any external matter on this attractor, v) can become the main (and possibly the only) source of DM, provided the shift-symmetry in the HD terms is broken during some small time interval in the radiation domination era. In the second ...

  11. White matter involvement in sporadic Creutzfeldt-Jakob disease.

    Science.gov (United States)

    Caverzasi, Eduardo; Mandelli, Maria Luisa; DeArmond, Stephen J; Hess, Christopher P; Vitali, Paolo; Papinutto, Nico; Oehler, Abby; Miller, Bruce L; Lobach, Irina V; Bastianello, Stefano; Geschwind, Michael D; Henry, Roland G

    2014-12-01

    Sporadic Creutzfeldt-Jakob disease is considered primarily a disease of grey matter, although the extent of white matter involvement has not been well described. We used diffusion tensor imaging to study the white matter in sporadic Creutzfeldt-Jakob disease compared to healthy control subjects and to correlated magnetic resonance imaging findings with histopathology. Twenty-six patients with sporadic Creutzfeldt-Jakob disease and nine age- and gender-matched healthy control subjects underwent volumetric T1-weighted and diffusion tensor imaging. Six patients had post-mortem brain analysis available for assessment of neuropathological findings associated with prion disease. Parcellation of the subcortical white matter was performed on 3D T1-weighted volumes using Freesurfer. Diffusion tensor imaging maps were calculated and transformed to the 3D-T1 space; the average value for each diffusion metric was calculated in the total white matter and in regional volumes of interest. Tract-based spatial statistics analysis was also performed to investigate the deeper white matter tracts. There was a significant reduction of mean (P=0.002), axial (P=0.0003) and radial (P=0.0134) diffusivities in the total white matter in sporadic Creutzfeldt-Jakob disease. Mean diffusivity was significantly lower in most white matter volumes of interest (Pchanges in white matter anisotropy. Tract-based spatial statistics analysis showed significant reductions of mean diffusivity within the white matter of patients with sporadic Creutzfeldt-Jakob disease, mainly in the left hemisphere, with a strong trend (P=0.06) towards reduced mean diffusivity in most of the white matter bilaterally. In contrast, by visual assessment there was no white matter abnormality either on T2-weighted or diffusion-weighted images. Widespread reduction in white matter mean diffusivity, however, was apparent visibly on the quantitative attenuation coefficient maps compared to healthy control subjects

  12. Condensation of galactic cold dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Visinelli, Luca [Nordita, KTH Royal Institute of Technology and Stockholm University,SE-106 91 Stockholm (Sweden)

    2016-07-07

    We consider the steady-state regime describing the density profile of a dark matter halo, if dark matter is treated as a Bose-Einstein condensate. We first solve the fluid equation for “canonical” cold dark matter, obtaining a class of density profiles which includes the Navarro-Frenk-White profile, and which diverge at the halo core. We then solve numerically the equation obtained when an additional “quantum pressure” term is included in the computation of the density profile. The solution to this latter case is finite at the halo core, possibly avoiding the “cuspy halo problem” present in some cold dark matter theories. Within the model proposed, we predict the mass of the cold dark matter particle to be of the order of M{sub χ}c{sup 2}≈10{sup −24} eV, which is of the same order of magnitude as that predicted in ultra-light scalar cold dark matter models. Finally, we derive the differential equation describing perturbations in the density and the pressure of the dark matter fluid.

  13. Condensation of galactic cold dark matter

    Science.gov (United States)

    Visinelli, Luca

    2016-07-01

    We consider the steady-state regime describing the density profile of a dark matter halo, if dark matter is treated as a Bose-Einstein condensate. We first solve the fluid equation for ``canonical'' cold dark matter, obtaining a class of density profiles which includes the Navarro-Frenk-White profile, and which diverge at the halo core. We then solve numerically the equation obtained when an additional ``quantum pressure'' term is included in the computation of the density profile. The solution to this latter case is finite at the halo core, possibly avoiding the ``cuspy halo problem'' present in some cold dark matter theories. Within the model proposed, we predict the mass of the cold dark matter particle to be of the order of Mχ c2 ≈ 10-24 eV, which is of the same order of magnitude as that predicted in ultra-light scalar cold dark matter models. Finally, we derive the differential equation describing perturbations in the density and the pressure of the dark matter fluid.

  14. Dark matter in the universe

    Energy Technology Data Exchange (ETDEWEB)

    Turner, M.S. (Fermi National Accelerator Lab., Batavia, IL (USA) Chicago Univ., IL (USA). Enrico Fermi Inst.)

    1990-11-01

    What is the quantity and composition of material in the Universe This is one of the most fundamental questions we can ask about the Universe, and its answer bears on a number of important issues including the formation of structure in the Universe, and the ultimate fate and the earliest history of the Universe. Moreover, answering this question could lead to the discovery of new particles, as well as shedding light on the nature of the fundamental interactions. At present, only a partial answer is at hand: Most of the material in the Universe does not give off detectable radiation, i.e., is dark;'' the dark matter associated with bright galaxies contributes somewhere between 10% and 30% of the critical density (by comparison luminous matter contributes less than 1%); baryonic matter contributes between 1.1% and 12% of critical. The case for the spatially-flat, Einstein-de Sitter model is supported by three compelling theoretical arguments--structure formation, the temporal Copernican principle, and inflation--and by some observational data. If {Omega} is indeed unity--or even just significantly greater than 0.1--then there is a strong case for a Universe comprised of nonbaryonic matter. There are three well motivated particle dark-matter candidates: an axion of mass 10{sup {minus}6} eV to 10{sup {minus}4} eV; a neutralino of mass 10 GeV to about 3 TeV; or a neutrino of mass 20 eV to 90 eV. All three possibilities can be tested by experiments that are either being planned or are underway. 63 refs.

  15. Dark matter in the Universe

    Energy Technology Data Exchange (ETDEWEB)

    Turner, M.S. (Fermi National Accelerator Lab., Batavia, IL (USA) Chicago Univ., IL (USA). Enrico Fermi Inst.)

    1991-03-01

    What is the quantity and composition of material in the universe This is one of the most fundamental questions we can ask about the universe, and its answer bears on a number of important issues including the formation of structure in the universe, and the ultimate fate and the earliest history of the universe. Moreover, answering this question could lead to the discovery of new particles, as well as shedding light on the nature of the fundamental interactions. At present, only a partial answer is at hand: most of the material in the universe does not give off detectable radiation, i.e., is dark;'' the dark matter associated with bright galaxies contributes somewhere between 10% and 30% of the critical density (by comparison luminous matter contributes less than 1%); baryonic matter contributes between 1.1% and 12% of critical. The case for the spatially-flat, Einstein-de Sitter model is supported by three compelling theoretical arguments -- structure formation, the temporal Copernican principle, and inflation -- and by some observational data. If {Omega} is indeed unity--or even just significantly greater than 0.1--then there is a strong case for a universe comprised of nonbaryonic matter. There are three well motivated particle dark-matter candidates: an axion of mass 10{sup {minus}6} eV to 10{sup {minus}4} eV; a neutralino of mass 10 GeV to about 3 TeV; or a neutrino of mass 20 eV to 90 eV. All three possibilities can be tested by experiments that are either being planned or are underway. 71 refs., 6 figs.

  16. The Subjective Dimension of Nazism

    NARCIS (Netherlands)

    Föllmer, M.

    2013-01-01

    The present historiographical review discusses the subjective dimension of Nazism, an ideology and regime that needed translation into self-definitions, gender roles, and bodily practices to implant itself in German society and mobilize it for racial war. These studies include biographies of some of

  17. Updated galactic radio constraints on Dark Matter

    Science.gov (United States)

    Cirelli, Marco; Taoso, Marco

    2016-07-01

    We perform a detailed analysis of the synchrotron signals produced by dark matter annihilations and decays. We consider different set-ups for the propagation of electrons and positrons, the galactic magnetic field and dark matter properties. We then confront these signals with radio and microwave maps, including Planck measurements, from a frequency of 22 MHz up to 70 GHz. We derive two sets of constraints: conservative and progressive, the latter based on a modeling of the astrophysical emission. Radio and microwave constraints are complementary to those obtained with other indirect detection methods, especially for dark matter annihilating into leptonic channels.

  18. Updated galactic radio constraints on Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Cirelli, Marco [Laboratoire de Physique Théorique et Hautes Energies (LPTHE),UMR 7589 CNRS & UPMC, 4 Place Jussieu, Paris, F-75252 (France); Taoso, Marco [Instituto de Física Teórica (IFT) UAM/CSIC,calle Nicolás Cabrera 13-15, Cantoblanco, Madrid, 28049 (Spain)

    2016-07-25

    We perform a detailed analysis of the synchrotron signals produced by dark matter annihilations and decays. We consider different set-ups for the propagation of electrons and positrons, the galactic magnetic field and dark matter properties. We then confront these signals with radio and microwave maps, including PLANCK measurements, from a frequency of 22 MHz up to 70 GHz. We derive two sets of constraints: conservative and progressive, the latter based on a modeling of the astrophysical emission. Radio and microwave constraints are complementary to those obtained with other indirect detection methods, especially for dark matter annihilating into leptonic channels.

  19. Models of Supersymmetry for Dark Matter

    Directory of Open Access Journals (Sweden)

    Muñoz Carlos

    2017-01-01

    Full Text Available A brief review of supersymmetric models and their candidates for dark matter is carried out. The neutralino is a WIMP candidate in the MSSM where R-parity is conserved, but this model has the μ problem. There are natural solutions to this problem that necessarily introduce new structure beyond the MSSM, including new candidates for dark matter. In particular, in an extension of the NMSSM, the right-handed sneutrino can be used for this job. In R-parity violating models such as the μvSSM, the gravitino can be the dark matter, and could be detected by its decay products in gamma-ray experiments.

  20. Hidden photons in connection to dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Andreas, Sarah; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Goodsell, Mark D. [CPhT, Ecole Polytechnique, Palaiseau (France)

    2013-06-15

    Light extra U(1) gauge bosons, so called hidden photons, which reside in a hidden sector have attracted much attention since they are a well motivated feature of many scenarios beyond the Standard Model and furthermore could mediate the interaction with hidden sector dark matter.We review limits on hidden photons from past electron beam dump experiments including two new limits from such experiments at KEK and Orsay. In addition, we study the possibility of having dark matter in the hidden sector. A simple toy model and different supersymmetric realisations are shown to provide viable dark matter candidates in the hidden sector that are in agreement with recent direct detection limits.

  1. Communication About Sexual Matters With Women Attending a Danish Fertility Clinic: A Descriptive Study.

    Science.gov (United States)

    Eldridge, Katrine Fiil; Giraldi, Annamaria

    2017-09-01

    Several studies have shown that sexuality is an important aspect of life. Nevertheless, sexual matters are only rarely discussed between patients and doctors. Other studies have suggested that women undergoing fertility treatment compose a group of patients with low satisfaction in their sexual life. To investigate how women at a fertility clinic desire and experience communication about sexual matters with doctors and to investigate the sexual function of these women. A cross-sectional self-administered questionnaire survey of women attending a Danish fertility clinic over 4 months was performed. Descriptive statistics were calculated and presented as frequencies. Communication about sexual matters with doctors included the women's comfort, preferred and actual frequency of discussion, and initiation of the conversation. Sexual function included participants' sexuality during the past year including certain sexual difficulties. Of the 201 participating women in the survey, most felt comfortable discussing sexual matters with doctors and preferred gynecologists for such discussions. There was a greater desire for communication than what was actually experienced by the women, and most wanted to initiate the conversation themselves. The women were less satisfied with their sexual life compared with a national control group, and they experienced sexual difficulties more often. There is an unmet desire of women in fertility treatment for discussing sexual matters, and greater communication on this subject needs to be clinically implemented. Eldridge KE, Giraldi A. Communication About Sexual Matters With Women Attending a Danish Fertility Clinic. A Descriptive Study. Sex Med 2017;5:e196-e202. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  2. Ribcage compressibility in living subjects.

    Science.gov (United States)

    Lee, M; Hill, S; Scullin, J

    1994-11-01

    The purpose of this study was to examine the responses of normal living subjects to the application of anteroposterior forces to the ribcage. Seventeen subjects aged between 25 and 37 years were tested during slow oscillatory loading while breath-holding at the end of a normal expiration. The mean stiffness coefficient was found to be 9.4 N mm(-1) (SD 2.9) and the mean gradient of the force-strain relation was 1888 N (SD 646). Comparison with previously published cadaver data indicates that the embalmed cadaver ribcage stiffness is in the order of three times stiffer than living subjects, while fresh cadavers showed comparable stiffness to living subjects. A number of studies have used models to predict and understand the behaviour of the thoracic spine. Validation of the behaviour of models which include the thoracic spine and ribcage depends on comparison of model response predictions with observed responses of human subjects. The present study provides data on the anteroposterior compressibility of the ribcage of living subjects which may be suitable for use in model validation studies. Copyright © 1994. Published by Elsevier Ltd.

  3. International Energy: Subject Thesaurus

    Energy Technology Data Exchange (ETDEWEB)

    Raridon, M.H. (ed.)

    1990-01-01

    The International Energy Subject Thesaurus contains the standard vocabulary to indexing terms (descriptors) developed and structured to build and maintain energy information databases. Involved in this cooperative task are (1) the technical staff of the USDOE Office of Scientific and Technical Information (OSTI) in cooperation with the member countries of the Energy Technology Data Exchange (ETDE) and (2) the International Nuclear Information System (INIS) staff representing the more than ninety countries and organizations recording and indexing information for the international nuclear information community. ETDE member countries are also members of the International Nuclear Information System (INIS). Nuclear information indexed and recorded for INIS by these ETDE member countries is also included in the ETDE Energy Data Base, and indexing terminology is therefore cooperatively standardized for use in both information systems. This structured vocabulary reflects the scope of international energy research, development, and technological programs and encompasses terminology derived not only from the basic sciences but also from the areas of energy resources, conservation, safety, environmental impact, and regulation.

  4. To the Issue of the Subject Definition of Pedagogic Acmeology

    Directory of Open Access Journals (Sweden)

    N. K. Tchapayev

    2012-01-01

    Full Text Available The paper investigates the subject of pedagogic acmeology as an evolving phenomenon integrating a complex set of pedagogic, psychological, anthropological and socially significant characteristics. The methodology framework is based on dialectics – «the only method that can grasp a living reality on the whole» (A. F. Losev. As the result, the author comes up with his own definition of pedagogic acmeology as a science dealing with the conformities and ways of developing the human potential and aimed at the positive personal achievements in educational process; wherein the man is regarded as the human subject, individual and individuality - i.e. a holistic multidimensional personality. The significant conclusion of the study involves the idea that pedagogic acmeology should not be confined to teacher’s professional activities, as it was previously stated, but should include the activities of a learner as a growing and developing human being. In other words, pedagogic acmeology should overcome the age restrictions confining its subject matters to the adult’s activities. 

  5. To the Issue of the Subject Definition of Pedagogic Acmeology

    Directory of Open Access Journals (Sweden)

    N. K. Tchapayev

    2015-02-01

    Full Text Available The paper investigates the subject of pedagogic acmeology as an evolving phenomenon integrating a complex set of pedagogic, psychological, anthropological and socially significant characteristics. The methodology framework is based on dialectics – «the only method that can grasp a living reality on the whole» (A. F. Losev. As the result, the author comes up with his own definition of pedagogic acmeology as a science dealing with the conformities and ways of developing the human potential and aimed at the positive personal achievements in educational process; wherein the man is regarded as the human subject, individual and individuality - i.e. a holistic multidimensional personality. The significant conclusion of the study involves the idea that pedagogic acmeology should not be confined to teacher’s professional activities, as it was previously stated, but should include the activities of a learner as a growing and developing human being. In other words, pedagogic acmeology should overcome the age restrictions confining its subject matters to the adult’s activities. 

  6. Estimating Subjective Probabilities

    DEFF Research Database (Denmark)

    Andersen, Steffen; Fountain, John; Harrison, Glenn W.

    Subjective probabilities play a central role in many economic decisions, and act as an immediate confound of inferences about behavior, unless controlled for. Several procedures to recover subjective probabilities have been proposed, but in order to recover the correct latent probability one must...

  7. Estimating Subjective Probabilities

    DEFF Research Database (Denmark)

    Andersen, Steffen; Fountain, John; Harrison, Glenn W.

    2014-01-01

    Subjective probabilities play a central role in many economic decisions and act as an immediate confound of inferences about behavior, unless controlled for. Several procedures to recover subjective probabilities have been proposed, but in order to recover the correct latent probability one must ...

  8. Subjective meaning: an introduction

    NARCIS (Netherlands)

    van Wijnbergen-Huitink, Janneke; van Wijbergen-Huitink, Janneke; Meier, Cécile

    This introductory chapter traces some of the considerations on the basis of which relativistic approaches to subjective meaning became en vogue. In doing so, the chapter provides an overview of the relevant linguistic and philosophical issues when developing a treatment of subjectivity. In addition,

  9. Subjective safety in traffic.

    NARCIS (Netherlands)

    2012-01-01

    The term ‘subjective safety in traffic’ refers to people feeling unsafe in traffic or, more generally, to anxiety regarding being unsafe in traffic for oneself and/or others. Subjective safety in traffic can lead to road users limiting their mobility and social activities, which is one of the

  10. Subjective poverty line definitions

    NARCIS (Netherlands)

    J. Flik; B.M.S. van Praag (Bernard)

    1991-01-01

    textabstractIn this paper we will deal with definitions of subjective poverty lines. To measure a poverty threshold value in terms of household income, which separates the poor from the non-poor, we take into account the opinions of all people in society. Three subjective methods will be discussed

  11. D-Matter

    OpenAIRE

    Shiu, Gary; Wang, Lian-Tao

    2003-01-01

    We study the properties and phenomenology of particle-like states originating from D-branes whose spatial dimensions are all compactified. They are non-perturbative states in string theory and we refer to them as D-matter. In contrast to other non-perturbative objects such as 't Hooft-Polyakov monopoles, D-matter states could have perturbative couplings among themselves and with ordinary matter. The lightest D-particle (LDP) could be stable because it is the lightest state carrying certain (i...

  12. Unifying Subjectivity and Objectivity

    Directory of Open Access Journals (Sweden)

    Murugesan Chandrasekaran

    2016-10-01

    Full Text Available The contribution of modern science to the progress of civilization is immeasurable. Even its tendency toward exclusive concentration on the objective world has had salutary effects of great value. Modern science has wiped away much that was merely superstitious or speculative. Its rejection of unfounded opinions and prejudices has helped the thinking mind question conventional beliefs, shed preferences and prejudices, and challenge established authority. But modern systems thinking inherited from natural science is the suppression of the subjective dimension of reality. Many complex systems are an attempt to define and represent all subjective experience in physical terms. The modern man has a bias towards objectivity. The powerful influence of sense impressions on his mind and thinking makes him ignore the subjective experience and consider only objective facts as a valid, legitimate and representation of reality. Observing objective factors that are physical is easier than observing subjective factors that are subtle. The mechanistic view of reality has led to the rejection of the role of the individual in social development as insignificant. The individuals determine the development of society. Their social power has its roots both in subjective factors and objective factors. Economy, politics, society, and culture are inseparable dimensions of a single integrated reality. Subject and object constitute an integrated whole. The mind sees them as separate and independent. Or it views one as completely subordinate to the other. Unbiased approach to the study of all human experiences may prove that subject and object are interdependent dimensions or elements of reality.

  13. Coupled-cluster calculations of nucleonic matter

    Science.gov (United States)

    Hagen, G.; Papenbrock, T.; Ekström, A.; Wendt, K. A.; Baardsen, G.; Gandolfi, S.; Hjorth-Jensen, M.; Horowitz, C. J.

    2014-01-01

    considerably improved convergence than their local cousins. We are unable to find values for the parameters of the short-range part of the local 3NF that simultaneously yield acceptable values for the saturation point in symmetric nuclear matter and the binding energies of light nuclei. Conclusions: Coupled-cluster calculations with nuclear interactions from chiral EFT yield nonperturbative results for the EoS of nucleonic matter. Finite-size effects and effects of truncations can be controlled. For the optimization of chiral forces, it might be useful to include the saturation point of symmetric nuclear matter.

  14. Energy data base: subject thesaurus

    Energy Technology Data Exchange (ETDEWEB)

    Redford, J.S. (ed.)

    1981-10-01

    The technical staff of the DOE Technical Information Center, during its subject indexing activities, develops and structures a vocabulary that allows consistent machine storage and retrieval of information necessary to the accomplishment of the DOE mission. This thesaurus incorporates that structured vocabulary. The terminology of this thesaurus is used for the subject control of information announced in DOE Energy Research Abstracts, Energy Abstracts for Policy Analysis, and various update journals and bulletins in specialized areas. This terminology also facilitates subject searching of the DOE Energy Data Base on the DOE/RECON on-line retrieval system and on other commercial retrieval systems. The rapid expansion of the DOE's activities will result in a commitant thesaurus expansion as information relating to new activities is indexed. Only the terms used in the indexing of documents at the Technical Information Center to date are included. (JSR)

  15. Cleaning up dark matter

    CERN Multimedia

    Bignami, Giovanni Fabrizio

    2006-01-01

    "An experiment in Italy has found tantalizing but puzzling evidence for axions, one if the leading candidates for dark matter. The authors explain how a pair of spinning neutron stars should settle the issue once and for all." (3 pages)

  16. Boiling Primordial Matter: 1968

    CERN Document Server

    Hagedorn, Rolf

    2016-01-01

    This introductory article presents in popular language how the view of the early Universe was evolving through 1968 under the influence of than new and recent insights about the thermodynamic properties of strongly interacting matter (by JR, editor).

  17. Dark matter warms up

    CERN Multimedia

    Peplow, Mark

    2006-01-01

    "Unseen mass looks to be more "tepid" than thought. Astronomers have measured the temperature of dark matter for the first time. The discovery should help particle hunters to identify exactly what this mysterious substance is made of" (1 page)

  18. Matter Tracking Information System -

    Data.gov (United States)

    Department of Transportation — The Matter Tracking Information System (MTIS) principle function is to streamline and integrate the workload and work activity generated or addressed by our 300 plus...

  19. Little composite dark matter.

    Science.gov (United States)

    Balkin, Reuven; Perez, Gilad; Weiler, Andreas

    2018-01-01

    We examine the dark matter phenomenology of a composite electroweak singlet state. This singlet belongs to the Goldstone sector of a well-motivated extension of the Littlest Higgs with T -parity. A viable parameter space, consistent with the observed dark matter relic abundance as well as with the various collider, electroweak precision and dark matter direct detection experimental constraints is found for this scenario. T -parity implies a rich LHC phenomenology, which forms an interesting interplay between conventional natural SUSY type of signals involving third generation quarks and missing energy, from stop-like particle production and decay, and composite Higgs type of signals involving third generation quarks associated with Higgs and electroweak gauge boson, from vector-like top-partners production and decay. The composite features of the dark matter phenomenology allows the composite singlet to produce the correct relic abundance while interacting weakly with the Higgs via the usual Higgs portal coupling [Formula: see text], thus evading direct detection.

  20. RUSSIAN LAW SUBJECTS

    Directory of Open Access Journals (Sweden)

    D.N. Bakhrakh

    2006-03-01

    Full Text Available The question about the subjects of law branches is concerning the number of most important and difficult in law science. Its right decision influences on the subject of law regulation, precise definition of addressees of law norms, the volume of their rights and duties, the limits of action of norms of Main part of the branch, its principles. Scientific investigations, dedicated to law subjects system, promote the development of recommendations for the legislative and law applying activity; they are needed for scientific work organization and student training, for preparing qualified lawyers.

  1. White matter changes and diabetes predict cognitive decline in the elderly: the LADIS study

    DEFF Research Database (Denmark)

    Verdelho, A; Madureira, S; Moleiro, C

    2010-01-01

    We aimed to study if age-related white matter changes (WMC) and vascular risk factors were predictors of cognitive decline in elderly subjects with WMC living independently.......We aimed to study if age-related white matter changes (WMC) and vascular risk factors were predictors of cognitive decline in elderly subjects with WMC living independently....

  2. Breakfast staple types affect brain gray matter volume and cognitive function in healthy children.

    Science.gov (United States)

    Taki, Yasuyuki; Hashizume, Hiroshi; Sassa, Yuko; Takeuchi, Hikaru; Asano, Michiko; Asano, Kohei; Kawashima, Ryuta

    2010-12-08

    Childhood diet is important for brain development. Furthermore, the quality of breakfast is thought to affect the cognitive functioning of well-nourished children. To analyze the relationship among breakfast staple type, gray matter volume, and intelligence quotient (IQ) in 290 healthy children, we used magnetic resonance images and applied voxel-based morphometry. We divided subjects into rice, bread, and both groups according to their breakfast staple. We showed that the rice group had a significantly larger gray matter ratio (gray matter volume percentage divided by intracranial volume) and significantly larger regional gray matter volumes of several regions, including the left superior temporal gyrus. The bread group had significantly larger regional gray and white matter volumes of several regions, including the right frontoparietal region. The perceptual organization index (POI; IQ subcomponent) of the rice group was significantly higher than that of the bread group. All analyses were adjusted for age, gender, intracranial volume, socioeconomic status, average weekly frequency of having breakfast, and number of side dishes eaten for breakfast. Although several factors may have affected the results, one possible mechanism underlying the difference between the bread and the rice groups may be the difference in the glycemic index (GI) of these two substances; foods with a low GI are associated with less blood-glucose fluctuation than are those with a high GI. Our study suggests that breakfast staple type affects brain gray and white matter volumes and cognitive function in healthy children; therefore, a diet of optimal nutrition is important for brain maturation during childhood and adolescence.

  3. Breakfast staple types affect brain gray matter volume and cognitive function in healthy children.

    Directory of Open Access Journals (Sweden)

    Yasuyuki Taki

    Full Text Available Childhood diet is important for brain development. Furthermore, the quality of breakfast is thought to affect the cognitive functioning of well-nourished children. To analyze the relationship among breakfast staple type, gray matter volume, and intelligence quotient (IQ in 290 healthy children, we used magnetic resonance images and applied voxel-based morphometry. We divided subjects into rice, bread, and both groups according to their breakfast staple. We showed that the rice group had a significantly larger gray matter ratio (gray matter volume percentage divided by intracranial volume and significantly larger regional gray matter volumes of several regions, including the left superior temporal gyrus. The bread group had significantly larger regional gray and white matter volumes of several regions, including the right frontoparietal region. The perceptual organization index (POI; IQ subcomponent of the rice group was significantly higher than that of the bread group. All analyses were adjusted for age, gender, intracranial volume, socioeconomic status, average weekly frequency of having breakfast, and number of side dishes eaten for breakfast. Although several factors may have affected the results, one possible mechanism underlying the difference between the bread and the rice groups may be the difference in the glycemic index (GI of these two substances; foods with a low GI are associated with less blood-glucose fluctuation than are those with a high GI. Our study suggests that breakfast staple type affects brain gray and white matter volumes and cognitive function in healthy children; therefore, a diet of optimal nutrition is important for brain maturation during childhood and adolescence.

  4. Development of Web Based Learning Material in Physics Subject for Kalor and Temperature Material

    Directory of Open Access Journals (Sweden)

    Fatwa Aji Kurniawan

    2015-12-01

    Full Text Available It has been done, the research which aims to develop a web-based teaching materials on the subjects of physics subject with subject mater of temperature and heat. This study using a modified model of the 4D development by eliminating the deployment phase. The validation of product development conducted by validator media experts and experts matter of physics, whereas small-scale trials conducted by physics teacher and 10 students. Validator review results stating that the quality of the product development were included in the category very well with the average percentage rating of 83.93%. The percentage value assigned by media expert by 75% in the good category and the percentage of the value provided by a matter expert 92.85% were in the very good category. Experiments by physics teacher to obtain result of equal to 94.44% were in the very good category and the average percentage of the test results by the students of 90.5% were in the very good category. The characteristics of the products developed include material composition using the curriculum in 2013, there was a recording facility and the results of evaluation of students' activities, there were feedback evaluation results were immediately known by the students and there were some links related to the material either youtube or other learning website.

  5. Dense cold matter

    Directory of Open Access Journals (Sweden)

    Stavinskiy Alexey

    2016-01-01

    Full Text Available The possibility to study cold nuclear matter with the density of neutron star core and even larger in the laboratory experiment is discussed. Special rare kinematical trigger for relativistic ion-ion collisions is proposed for such study. Expected properties of the matter in such unusual conditions and experimental program for its study is discussed. Possible experimental setup and R&D results for position sensitive neutron detector are presented.

  6. Matter-antimatter Cosmology

    Science.gov (United States)

    Omnes, R.

    1973-01-01

    The possible existence of antimatter on a large scale in the universe is evaluated. As a starting point, an attempt was made to understand the origin of matter as being essentially analogous to the origin of backgound thermal radiation. Several theories and models are examined, with particular emphasis on nucleon-antinucleon interactions at intermediate energies. Data also cover annihilation interaction with the matter-antimatter boundary to produce the essential fluid motion known as coalesence.

  7. Does size really matter?

    DEFF Research Database (Denmark)

    Hansen, Maj; Hyland, Philip; Karstoft, Karen-Inge

    2017-01-01

    words, does the size of PTSD really matter? Methods: The aim was investigated by examining differences in diagnostic rates between the two diagnostic systems and independently examining the model fit of the competing DSM-5 and ICD-11 models of PTSD across three trauma samples: university students (N...... diagnostic criteria only the ICD-11 model can reflect the configuration of symptoms satisfactorily. Thus, size does matter when assessing PTSD....

  8. Charming dark matter

    OpenAIRE

    Jubb, Thomas; Kirk, Matthew; Lenz, Alexander

    2017-01-01

    We have considered a model of Dark Minimal Flavour Violation (DMFV), in which a triplet of dark matter particles couple to right-handed up-type quarks via a heavy colour-charged scalar mediator. By studying a large spectrum of possible constraints, and assessing the entire parameter space using a Markov Chain Monte Carlo (MCMC), we can place strong restrictions on the allowed parameter space for dark matter models of this type.

  9. Experimental Implications of Mirror Matter-Type Dark Matter

    Science.gov (United States)

    Foot, Robert

    Mirror matter-type dark matter is one dark matter candidate which is particularly well motivated from high energy physics. The theoretical motivation and experimental evidence are pedagogically reviewed, with emphasis on the implications of recent orthopositronium experiments, the DAMA/NaI dark matter search, anomalous meteorite events etc.

  10. Subjectivity and severe psychiatric disorders.

    Science.gov (United States)

    Strauss, John

    2011-01-01

    To have a complete human science in the mental health field it is essential to give adequate attention to both the objective and the subjective data related to people with psychiatric disorders. The tendency in the past has been to ignore or discount one or the other of these data sources. Subjective data are particularly neglected, sometimes considered (only) part of the "art" of medicine since the usual methodologies of the physical sciences in themselves are not adequate to reflect the nature, elusiveness, and complexity of human subjective experience. The complete experience of hallucinated voices, for instance, often includes not only the voices themselves but also terrible anguish and terrifying inability to concentrate. But even such descriptors fall unnecessarily short of reflecting the data of the experience, thus leaving research, theory, and treatment with incomplete information. To represent adequately the subjective data it is essential to recognize that besides the usual discursive knowledge and methods of traditional physical science, a second kind of knowledge and method is required to reflect the depth of human experience. To accomplish this, we must employ approaches to narrative and the arts that are uniquely capable of capturing the nature of these experiences. Only by attending seriously in our research, training, theory, and practice to the unique nature of subjective data is it possible to have a true human science for our field.

  11. [Reproducibility of subjective refraction measurement].

    Science.gov (United States)

    Grein, H-J; Schmidt, O; Ritsche, A

    2014-11-01

    Reproducibility of subjective refraction measurement is limited by various factors. The main factors affecting reproducibility include the characteristics of the measurement method and of the subject and the examiner. This article presents the results of a study on this topic, focusing on the reproducibility of subjective refraction measurement in healthy eyes. The results of previous studies are not all presented in the same way by the respective authors and cannot be fully standardized without consulting the original scientific data. To the extent that they are comparable, the results of our study largely correspond largely with those of previous investigations: During repeated subjective refraction measurement, 95% of the deviation from the mean value was approximately ±0.2 D to ±0.65 D for the spherical equivalent and cylindrical power. The reproducibility of subjective refraction measurement in healthy eyes is limited, even under ideal conditions. Correct assessment of refraction results is only feasible after identifying individual variability. Several measurements are required. Refraction cannot be measured without a tolerance range. The English full-text version of this article is available at SpringerLink (under supplemental).

  12. The Specific Heat of Matter at Low Temperatures

    CERN Document Server

    Tari, A

    2003-01-01

    Recent discoveries of new materials and improvements in calorimetric techniques have given new impetus to the subject of specific heat. Nevertheless, there is a serious lack of literature on the subject. This invaluable book, which goes some way towards remedying that, is concerned mainly with the specific heat of matter at ordinary temperatures. It discusses the principles that underlie the theory of specific heat and considers a number of theoretical models in some detail. The subject matter ranges from traditional materials to those recently discovered - heavy fermion compounds, high temper

  13. Danish emission inventory for particular matter (PM)

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, M.; Winther, M.; Illerup, J.B.; Hjort Mikkelsen, M.

    2003-11-01

    The first Danish emission inventory that was reported in 2002 was a provisional-estimate based on data presently available. This report documents methodology, emission factors and references used for an improved Danish emission inventory for particulate matter. Further results of the improved emission inventory for the year 2000 are shown. The particulate matter emission inventory includes TSP, PM,, and PM, The report covers emission inventories for transport and stationary combustion. An appendix covering emissions from agriculture is also included. For the transport sector, both exhaust and non-exhaust emission such as tyre and break wear and road abrasion are included. (au)

  14. The Data Subject

    DEFF Research Database (Denmark)

    Blume, Peter

    2015-01-01

    This article considers whether it is fortunate that data protection rules, as a starting point, apply to all physical persons as data subjects, or whether it would be better to differentiate between kinds of persons on grounds of their ability to act as a data subject. In order to protect all...... persons, it is argued that a principle of care should be part of data protection law....

  15. Field theories of condensed matter physics

    CERN Document Server

    Fradkin, Eduardo

    2013-01-01

    Presenting the physics of the most challenging problems in condensed matter using the conceptual framework of quantum field theory, this book is of great interest to physicists in condensed matter and high energy and string theorists, as well as mathematicians. Revised and updated, this second edition features new chapters on the renormalization group, the Luttinger liquid, gauge theory, topological fluids, topological insulators and quantum entanglement. The book begins with the basic concepts and tools, developing them gradually to bring readers to the issues currently faced at the frontiers of research, such as topological phases of matter, quantum and classical critical phenomena, quantum Hall effects and superconductors. Other topics covered include one-dimensional strongly correlated systems, quantum ordered and disordered phases, topological structures in condensed matter and in field theory and fractional statistics.

  16. Aging of cerebral white matter.

    Science.gov (United States)

    Liu, Huan; Yang, Yuanyuan; Xia, Yuguo; Zhu, Wen; Leak, Rehana K; Wei, Zhishuo; Wang, Jianyi; Hu, Xiaoming

    2017-03-01

    White matter (WM) occupies a large volume of the human cerebrum and is mainly composed of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are the structural foundation for efficient neurotransmission between cortical and subcortical areas. Similar to neuron-enriched gray matter areas, WM undergoes a series of changes during the process of aging. WM malfunction can induce serious neurobehavioral and cognitive impairments. Thus, age-related changes in WM may contribute to the functional decline observed in the elderly. In addition, aged WM becomes more susceptible to neurological disorders, such as stroke, traumatic brain injury (TBI), and neurodegeneration. In this review, we summarize the structural and functional alterations of WM in natural aging and speculate on the underlying mechanisms. We also discuss how age-related WM changes influence the progression of various brain disorders, including ischemic and hemorrhagic stroke, TBI, Alzheimer's disease, and Parkinson's disease. Although the physiology of WM is still poorly understood relative to gray matter, WM is a rational therapeutic target for a number of neurological and psychiatric conditions. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. Subjective response to foot-fall noise, including localization of the source position

    DEFF Research Database (Denmark)

    Brunskog, Jonas; Hwang, Ha Dong; Jeong, Cheol-Ho

    2011-01-01

    annoyance, using simulated binaural room impulse responses, with sources being a moving point source or a non-moving surface source, and rooms being a room with a reverberation time of 0.5 s or an anechoic room. The paper concludes that no strong effect of the source localization on the annoyance can...

  18. Aciduric microbial taxa including Scardovia wiggsiae and Bifidobacterium spp. in caries and caries free subjects.

    Science.gov (United States)

    Henne, Karsten; Rheinberg, Anke; Melzer-Krick, Beate; Conrads, Georg

    2015-10-01

    Actinobacteria came into focus of being potential caries-associated pathogens and could, together with the established Streptococcus mutans and lactobacilli thus function as caries indicator species. Here we analyzed the role and diagnostic predictive value of the acidogenic-aciduric species Scardovia wiggsiae and Bifidobacterium dentium together with S. mutans, lactobacilli and bifidobacteria in biofilm of non-cavitated (n = 20) and cavitated (n = 6) caries lesions versus controls (n = 30). For the genus Bifidobacterium and for B. dentium new sets of primers were designed. Based on real-time quantitative PCR and confirmed by DNA sequencing we found a higher prevalence (61.5%) of S. wiggsiae in caries lesions than in controls (40%). However, among the controls we found three individuals with both the highest absolute and relative S. wiggsiae numbers. Testing for S. mutans revealed the same prevalence as S. wiggsiae in caries lesions (61.5%) but in controls its prevalence was only 10%. B. dentium was never found in healthy plaque but in 30.8% of clinical cases, with the highest numbers in cavitated lesions. The Bifidobacterium-genus specific PCR had less discriminative power as more control samples were positive. We calculated the relative abundances and applied receiver operating characteristic analyses. The top results of specificity (93% and 87%) and sensitivity (100% and 88%) were found when the constraint set was "Lactobacillus relative abundance ≥0.02%" and "two aciduric species with a relative abundance of each ≥0.007%". Combinatory measurement of several aciduric taxa may be useful to reveal caries activity or even to predict caries progression. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Voice, Post-Structural Representation and the Subjectivity of "Included" Students

    Science.gov (United States)

    Whitburn, Ben

    2016-01-01

    Aligned with the broader movement from structuralism to the post-structuralisms [Lather, P. 2013. "Methodology-21: What Do We Do in the Afterward?" "International Journal of Qualitative Studies in Education" 26 (6): 634-645; St. Pierre, E. A. 2009. "Afterword: Decentering Voice in Qualitative Inquiry." In "Voice…

  20. [Can men be included in the population subjected to puerperal psychosis? A case report].

    Science.gov (United States)

    Colombel, M; Rebillard, C; Nathou, C; Dollfus, S

    2016-08-01

    Puerperal psychosis (PP) is a psychiatric disorder that occurs in 1 out of 1000 pregnancies. Well known since antiquity, its symptoms have often been described in mothers, but few studies have successfully investigated a related disorder in fathers. The characteristic of this pathology is more related to its appearance than to its semiological description which is why its nosographic place is always discussed. The objective here is to focus on the definition of PP and to suggest an entity for both genders. Our case report focused on the clinical description of an eighteen-year-old man suffering from an acute psychosis episode that occurred around the birth of his first child. Delusion followed a sudden decline in mood that lasted for a short period of time during the course of the third trimester of his wife's pregnancy. The delirium was rich with auditory and cenesthesic hallucinations, pregnancy and birth denial, feeling movements and hearing voices in his stomach. The symptoms disappeared after one month of treatment via an antipsychotic drug, risperidone. We can confirm that the symptomatic description of the disorder in this patient fits the classical descriptions of PP. Two elements make the PP different from other acute psychoses: the context of pregnancy and delirium focused on the child which can lead to a child murder. The absence of a framework precisely defining the PP does not improve its prevention and can lead to legal attitudes rather than medical care. Men suffering from acute psychosis in a context of pregnancy are submitted to the same risks as women. It is necessary to emphasize descriptions of PP in men to redefine the disease and consider that this entity involves both men and women. Copyright © 2016 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  1. A score including ADAM17 substrates correlates to recurring cardiovascular event in subjects with atherosclerosis.

    Science.gov (United States)

    Rizza, Stefano; Copetti, Massimiliano; Cardellini, Marina; Menghini, Rossella; Pecchioli, Chiara; Luzi, Alessio; Di Cola, Giovanni; Porzio, Ottavia; Ippoliti, Arnaldo; Romeo, Franco; Pellegrini, Fabio; Federici, Massimo

    2015-04-01

    Atherosclerosis disease is a leading cause for mortality and morbidity. The narrowing/rupture of a vulnerable atherosclerotic plaque is accountable for acute cardiovascular events. However, despite of an intensive research, a reliable clinical method which may disclose a vulnerable patient is still unavailable. We tested the association of ADAM17 (A Disintegrin and Metallo Protease Domain 17) circulating substrates (sICAM-1, sVCAM-1, sIL6R and sTNFR1) with a second major cardiovascular events [MACEs] (cardiovascular death, peripheral artery surgeries, non-fatal myocardial infarction and non-fatal stroke) in 298 patients belonging to the Vascular Diabetes (AVD) study. To evaluate ADAM17 activity we create ADAM17 score through a RECPAM model. Finally we tested the discrimination ability and the reclassification of clinical models. At follow-up (mean 47 months, range 1-118 months), 55 MACEs occurred (14 nonfatal MI, 14 nonfatal strokes, 17 peripheral artery procedures and 10 cardiovascular deaths) (incidence = 7.8% person-years). An increased risk for incident events was observed among the high ADAM17 score individuals both in univariable (HR 19.20, 95% CI 15.82-63.36, p atherosclerosis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  2. Correlated electrons in quantum matter

    CERN Document Server

    Fulde, Peter

    2012-01-01

    An understanding of the effects of electronic correlations in quantum systems is one of the most challenging problems in physics, partly due to the relevance in modern high technology. Yet there exist hardly any books on the subject which try to give a comprehensive overview on the field covering insulators, semiconductors, as well as metals. The present book tries to fill that gap. It intends to provide graduate students and researchers a comprehensive survey of electron correlations, weak and strong, in insulators, semiconductors and metals. This topic is a central one in condensed matter and beyond that in theoretical physics. The reader will have a better understanding of the great progress which has been made in the field over the past few decades.

  3. Dark matter in the universe

    Science.gov (United States)

    Turner, Michael S.

    1991-01-01

    What is the quantity and composition of material in the Universe? This is one of the most fundamental questions we can ask about the Universe, and its answer bears on a number of important issues including the formation of structure in the Universe, and the ultimate fate and the earliest history of the Universe. Moreover, answering this question could lead to the discovery of new particles, as well as shedding light on the nature of the fundamental interactions. At present, only a partial answer is at hand. Most of the radiation in the Universe does not give off detectable radiation; it is dark. The dark matter associated with bright galaxies contributes somewhere between 10 and 30 percent of the critical density; baryonic matter contributes between 1.1 and 12 percent of the critical. The case for the spatially flat, Einstein-de Sitter model is supported by three compelling theoretical arguments - structure formation, the temporal Copernican principle, and inflation - and by some observational data. If Omega is indeed unity, or even just significantly greater than 0.1, then there is a strong case for a Universe comprised of nonbaryonic matter. There are three well motivated particle dark matter candidates: an axion of mass 10 (exp -6) eV to 10 (exp -4) eV; a neutrino of mass 10 GeV to about 3 TeV; or a neutrino of mass 20 eV to 90 eV. All three possibilities can be tested by experiments that are either planned or are underway.

  4. Accelerated Gray and White Matter Deterioration With Age in Schizophrenia.

    Science.gov (United States)

    Cropley, Vanessa L; Klauser, Paul; Lenroot, Rhoshel K; Bruggemann, Jason; Sundram, Suresh; Bousman, Chad; Pereira, Avril; Di Biase, Maria A; Weickert, Thomas W; Weickert, Cynthia Shannon; Pantelis, Christos; Zalesky, Andrew

    2017-03-01

    Although brain changes in schizophrenia have been proposed to mirror those found with advancing age, the trajectory of gray matter and white matter changes during the disease course remains unclear. The authors sought to measure whether these changes in individuals with schizophrenia remain stable, are accelerated, or are diminished with age. Gray matter volume and fractional anisotropy were mapped in 326 individuals diagnosed with schizophrenia or schizoaffective disorder and in 197 healthy comparison subjects aged 20-65 years. Polynomial regression was used to model the influence of age on gray matter volume and fractional anisotropy at a whole-brain and voxel level. Between-group differences in gray matter volume and fractional anisotropy were regionally localized across the lifespan using permutation testing and cluster-based inference. Significant loss of gray matter volume was evident in schizophrenia, progressively worsening with age to a maximal loss of 8% in the seventh decade of life. The inferred rate of gray matter volume loss was significantly accelerated in schizophrenia up to middle age and plateaued thereafter. In contrast, significant reductions in fractional anisotropy emerged in schizophrenia only after age 35, and the rate of fractional anisotropy deterioration with age was constant and best modeled with a straight line. The slope of this line was 60% steeper in schizophrenia relative to comparison subjects, indicating a significantly faster rate of white matter deterioration with age. The rates of reduction of gray matter volume and fractional anisotropy were significantly faster in males than in females, but an interaction between sex and diagnosis was not evident. The findings suggest that schizophrenia is characterized by an initial, rapid rate of gray matter loss that slows in middle life, followed by the emergence of a deficit in white matter that progressively worsens with age at a constant rate.

  5. Use of ultracold neutrons for condensed-matter studies

    Energy Technology Data Exchange (ETDEWEB)

    Michaudon, A.

    1997-05-01

    Ultracold neutrons have such low velocities that they are reflected by most materials at all incident angles and can be stored in material bottles for long periods of time during which their intrinsic properties can be studied in great detail. These features have been mainly used for fundamental-physics studies including the detection of a possible neutron electric dipole moment and the precise determination of neutron-decay properties. Ultracold neutrons can also play a role in condensed-matter studies with the help of high-resolution spectrometers that use gravity as a strongly dispersive medium for low-velocity neutrons. Such studies have so far been limited by the low intensity of existing ultracold-neutron sources but could be reconsidered with more intense sources, which are now envisaged. This report provides a broad survey of the properties of ultracold neutrons (including their reflectivity by different types of samples), of ultracold-neutron spectrometers that are compared with other high-resolution instruments, of results obtained in the field of condensed matter with these instruments, and of neutron microscopes. All these subjects are illustrated by numerous examples.

  6. Neuronal pathology in deep grey matter structures: a multimodal imaging analysis combining PET and MRI

    Energy Technology Data Exchange (ETDEWEB)

    Bosque-Freeman, L.; Leroy, C.; Galanaud, D.; Sureau, F.; Assouad, R.; Tourbah, A.; Papeix, C.; Comtat, C.; Trebossen, R.; Lubetzki, C.; Delforge, J.; Bottlaender, M.; Stankoff, B. [Serv. Hosp. Frederic Joliot, Orsay (France)

    2009-07-01

    Objective: To assess neuronal damage in deep gray matter structures by positron emission tomography (PET) using [{sup 11}C]-flumazenil (FMZ), a specific central benzodiazepine receptor antagonist, and [{sup 18}F]-fluorodeoxyglucose (FDG), which reflects neuronal metabolism. To compare results obtained by PET and those with multimodal magnetic resonance imaging (MRI). Background: It is now accepted that neuronal injury plays a crucial role in the occurrence and progression of neurological disability in multiple sclerosis (MS). To date, available MRI techniques do not specifically assess neuronal damage, but early abnormalities, such as iron deposition or atrophy, have been described in deep gray matter structures. Whether those MRI modifications correspond to neuronal damage remains to be further investigated. Materials and methods: Nine healthy volunteers were compared to 10 progressive and 9 relapsing remitting (RR) MS patients. Each subject performed two PET examinations with [{sup 11}C]-FMZ and [{sup 18}F]-FDG, on a high resolution research tomograph dedicated to brain imaging (Siemens Medical Solution, spatial resolution of 2.5 mm). Deep gray matter regions were manually segmented on T1-weighted MR images with the mutual information algorithm (www.brainvisa.info), and co-registered with PET images. A multimodal MRI including T1 pre and post gadolinium, T2-proton density sequences, magnetization transfer, diffusion tensor, and protonic spectroscopy was also performed for each subject. Results: On PET with [{sup 11}C]-FMZ, there was a pronounced decrease in receptor density for RR patients in all deep gray matter structures investigated, whereas the density was unchanged or even increased in the same regions for progressive patients. Whether the different patterns between RR and progressive patients reflect distinct pathogenic mechanisms is currently investigated by comparing PET and multimodal MRI results. Conclusion: Combination of PET and multimodal MR imaging

  7. Haplotypes of catechol-O-methyltransferase modulate intelligence-related brain white matter integrity.

    Science.gov (United States)

    Liu, Bing; Li, Jun; Yu, Chunshui; Li, Yonghui; Liu, Yong; Song, Ming; Fan, Ming; Li, Kuncheng; Jiang, Tianzi

    2010-03-01

    Twin studies have indicated a common genetic origin for intelligence and for variations in brain morphology. Our previous diffusion tensor imaging studies found an association between intelligence and white matter integrity of specific brain regions or tracts. However, specific genetic determinants of the white matter integrity of these brain regions and tracts are still unclear. In this study, we assess whether and how catechol-O-methyltransferase (COMT) gene polymorphisms affect brain white matter integrity. We genotyped twelve single nucleotide polymorphisms (SNPs) within the COMT gene and performed haplotype analyses on data from 79 healthy subjects. Our subjects had the same three major COMT haplotypes (termed the HPS, APS and LPS haplotypes) as previous studies have reported as regulating significantly different levels of enzymatic activity and dopamine. We used the mean fractional anisotropy (FA) values from four regions and five tracts of interest to assess the effect of COMT polymorphisms, including the well-studied val158met SNP and the three main haplotypes that we had identified, on intelligence-related white matter integrity. We identified an association between the mean FA values of two regions in the bilateral prefrontal lobes and the COMT haplotypes, rather than between them and val158met. The haplotype-FA value associations modulated nonlinearly and fit an inverted U-model. Our findings suggest that COMT haplotypes can nonlinearly modulate the intelligence-related white matter integrity of the prefrontal lobes by more significantly influencing prefrontal dopamine variations than does val158met. Copyright (c) 2009 Elsevier Inc. All rights reserved.

  8. Asymmetric condensed dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Aguirre, Anthony; Diez-Tejedor, Alberto, E-mail: aguirre@scipp.ucsc.edu, E-mail: alberto.diez@fisica.ugto.mx [Santa Cruz Institute for Particle Physics and Department of Physics, University of California, Santa Cruz, CA, 95064 (United States)

    2016-04-01

    We explore the viability of a boson dark matter candidate with an asymmetry between the number densities of particles and antiparticles. A simple thermal field theory analysis confirms that, under certain general conditions, this component would develop a Bose-Einstein condensate in the early universe that, for appropriate model parameters, could survive the ensuing cosmological evolution until now. The condensation of a dark matter component in equilibrium with the thermal plasma is a relativistic process, hence the amount of matter dictated by the charge asymmetry is complemented by a hot relic density frozen out at the time of decoupling. Contrary to the case of ordinary WIMPs, dark matter particles in a condensate must be lighter than a few tens of eV so that the density from thermal relics is not too large. Big-Bang nucleosynthesis constrains the temperature of decoupling to the scale of the QCD phase transition or above. This requires large dark matter-to-photon ratios and very weak interactions with standard model particles.

  9. Entropy, matter, and cosmology.

    Science.gov (United States)

    Prigogine, I; Géhéniau, J

    1986-09-01

    The role of irreversible processes corresponding to creation of matter in general relativity is investigated. The use of Landau-Lifshitz pseudotensors together with conformal (Minkowski) coordinates suggests that this creation took place in the early universe at the stage of the variation of the conformal factor. The entropy production in this creation process is calculated. It is shown that these dissipative processes lead to the possibility of cosmological models that start from empty conditions and gradually build up matter and entropy. Gravitational entropy takes a simple meaning as associated to the entropy that is necessary to produce matter. This leads to an extension of the third law of thermodynamics, as now the zero point of entropy becomes the space-time structure out of which matter is generated. The theory can be put into a convenient form using a supplementary "C" field in Einstein's field equations. The role of the C field is to express the coupling between gravitation and matter leading to irreversible entropy production.

  10. Theory including future not excluded

    DEFF Research Database (Denmark)

    Nagao, K.; Nielsen, H.B.

    2013-01-01

    We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time T and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation......, Ehrenfest's theorem, and the conserved probability current density. In addition,we showthat the expectation value at the present time t of a future-included theory for large T - t and large t - T corresponds to that of a future-not-included theory with a proper inner product for large t - T. Hence, the CAT...

  11. Science of the subjective.

    Science.gov (United States)

    Jahn, R G; Dunne, B J

    2007-01-01

    Over the greater portion of its long scholarly history, the particular form of human observation, reasoning, and technical deployment we properly term "science" has relied at least as much on subjective experience and inspiration as it has on objective experiments and theories. Only over the past few centuries has subjectivity been progressively excluded from the practice of science, leaving an essentially secular analytical paradigm. Quite recently, however, a compounding constellation of newly inexplicable physical evidence, coupled with a growing scholarly interest in the nature and capability of human consciousness, are beginning to suggest that this sterilization of science may have been excessive and could ultimately limit its epistemological reach and cultural relevance. In particular, an array of demonstrable consciousness-related anomalous physical phenomena, a persistent pattern of biological and medical anomalies, systematic studies of mind/brain relationships and the mechanics of human creativity, and a burgeoning catalogue of human factors effects within contemporary information processing technologies, all display empirical correlations with subjective aspects that greatly complicate, and in many cases preclude, their comprehension on strictly objective grounds. However, any disciplined re-admission of subjective elements into rigorous scientific methodology will hinge on the precision with which they can be defined, measured, and represented, and on the resilience of established scientific techniques to their inclusion. For example, any neo-subjective science, while retaining the logical rigor, empirical/theoretical dialogue, and cultural purpose of its rigidly objective predecessor, would have the following requirements: acknowledgment of a proactive role for human consciousness; more explicit and profound use of interdisciplinary metaphors; more generous interpretations of measurability, replicability, and resonance; a reduction of ontological

  12. Dark matter searches in ATLAS

    CERN Document Server

    Diehl, Edward; The ATLAS collaboration

    2016-01-01

    Dark matter particles may be produced at the LHC in combination with other particles, typically from initial state radiation. We present results from the ATLAS experiment from searches for phenomena with jets, photons, heavy quarks, electroweak gauge bosons, or Higgs bosons recoiling against large missing transverse momentum. The measurements are interpreted using several theoretical frameworks including simplified models with pair production of Weakly Interacting Massive Particles, effective field theories, and other beyond the Standard Model scenarios. Constraints from dijet searches are compared with results from the “Mono-X” searches to provide a combined interpretation in the context of simplified models.

  13. WISPy cold dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Arias, Paola [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Pontificia Univ. Catolica de Chile, Santiago (Chile). Facultad de Fisica; Cadamuro, Davide; Redondo, Javier [Max-Planck-Institut fuer Physik, Muenchen (Germany); Goodsell, Mark [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); European Organization for Nuclear Research (CERN), Geneva (Switzerland); Jaeckel, Joerg [Durham Univ. (United Kingdom). Inst. for Particle Physics Phenomenology; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2012-01-15

    Very weakly interacting slim particles (WISPs), such as axion-like particles (ALPs) or hidden photons (HPs), may be non-thermally produced via the misalignment mechanism in the early universe and survive as a cold dark matter population until today. We find that, both for ALPs and HPs whose dominant interactions with the standard model arise from couplings to photons, a huge region in the parameter spaces spanned by photon coupling and ALP or HP mass can give rise to the observed cold dark matter. Remarkably, a large region of this parameter space coincides with that predicted in well motivated models of fundamental physics. A wide range of experimental searches - exploiting haloscopes (direct dark matter searches exploiting microwave cavities), helioscopes (searches for solar ALPs or HPs), or light-shining-through-a-wall techniques - can probe large parts of this parameter space in the foreseeable future. (orig.)

  14. Dark matter from unification

    DEFF Research Database (Denmark)

    Kainulainen, Kimmo; Tuominen, Kimmo; Virkajärvi, Jussi Tuomas

    2013-01-01

    We consider a minimal extension of the Standard Model (SM), which leads to unification of the SM coupling constants, breaks electroweak symmetry dynamically by a new strongly coupled sector and leads to novel dark matter candidates. In this model, the coupling constant unification requires...... eigenstates of this sector and determine the resulting relic density. The results are constrained by available data from colliders and direct and indirect dark matter experiments. We find the model viable and outline briefly future research directions....... the existence of electroweak triplet and doublet fermions singlet under QCD and new strong dynamics underlying the Higgs sector. Among these new matter fields and a new right handed neutrino, we consider the mass and mixing patterns of the neutral states. We argue for a symmetry stabilizing the lightest mass...

  15. Baryonic dark matter

    CERN Document Server

    Rebolo, R

    2002-01-01

    Recent determinations of baryonic density using the angular power spectrum of the Cosmic Microwave Background are very close to the classical estimate from Big Bang Nucleosynthesis. This reinforces the case for dark baryons in the Universe and for a large component of exotic cold dark matter. Present-day baryons can be hidden in substellar objects, stellar remnants, cold gas clouds, hot diffuse ionized gas in various astrophysical environments. Direct detection searches and microlensing experiments provide estimates of the Galactic mass budget in massive compact objects concluding that the bulk of the dark matter in the halo of the Galaxy cannot be associated to MACHOs. Baryons in high redshift Lyman-alpha systems can account for the cosmic baryonic density. However, the dominant form of present-day baryons and, in particular, the nature of the halo dark matter remains a mystery.

  16. Light, Matter, and Geometry

    DEFF Research Database (Denmark)

    Frisvad, Jeppe Revall

    Interaction of light and matter produces the appearance of materials. To deal with the immense complexity of nature, light and matter is modelled at a macroscopic level in computer graphics. This work is the first to provide the link between the microscopic physical theories of light and matter...... and the macroscopic process of rendering realistic images. This enables prediction of appearance based on the contents and the physical conditions of a material. The idea is to take the contents declaration for a material and use it to predict what the material looks like. Or conversely, to take a picture...... of a material and determine the contents of the material. The book is in four parts. Part I provides the link between microscopic and macroscopic theories of light. Part II describes how to use the properties of microscopic particles to compute the macroscopic properties of materials. Part III illustrates...

  17. WISPy Cold Dark Matter

    CERN Document Server

    Arias, Paola; Goodsell, Mark; Jaeckel, Joerg; Redondo, Javier; Ringwald, Andreas

    2012-01-01

    Very weakly interacting slim particles (WISPs), such as axion-like particles (ALPs) or hidden photons (HPs), may be non-thermally produced via the misalignment mechanism in the early universe and survive as a cold dark matter population until today. We find that, both for ALPs and HPs whose dominant interactions with the standard model arise from couplings to photons, a huge region in the parameter spaces spanned by photon coupling and ALP or HP mass can give rise to the observed cold dark matter. Remarkably, a large region of this parameter space coincides with that predicted in well motivated models of fundamental physics. A wide range of experimental searches -- exploiting haloscopes (direct dark matter searches exploiting microwave cavities), helioscopes (searches for solar ALPs or HPs), or light-shining-through-a-wall techniques -- can probe large parts of this parameter space in the foreseeable future.

  18. Natural minimal dark matter

    CERN Document Server

    Fabbrichesi, Marco

    2016-01-01

    We show how the Higgs boson mass is protected from the potentially large corrections due to the introduction of minimal dark matter if the new physics sector is made supersymmetric. The fermionic dark matter candidate (a 5-plet of $SU(2)_L$) is accompanied by a scalar state. The weak gauge sector is made supersymmetric and the Higgs boson is embedded in a supersymmetric multiplet. The remaining standard model states are non-supersymmetric. Non vanishing corrections to the Higgs boson mass only appear at three-loop level and the model is natural for dark matter masses up to 15 TeV--a value larger than the one required by the cosmological relic density. The construction presented stands as an example of a general approach to naturalness that solves the little hierarchy problem which arises when new physics is added beyond the standard model at an energy scale around 10 TeV.

  19. Dark matter searches

    Science.gov (United States)

    Bettini, Alessandro

    These lectures begin with a brief survey of the astrophysical and cosmological evidence for dark matter. We then consider the three principal theoretically motivated types of dark matter, sterile neutrinos, axions and SUSY WIMPs. In chapter 4 we discuss the motivations for the so-called neutrino minimal standard model, nuMSM, an extension of the SM with three sterile neutrinos with masses similar to the charged fermions. In chapter 5 we briefly recall the strong CP problem of the SM and the solution proposed by Peccei and Quinn leading to the prediction of axions and of their characteristics. We then discuss the experimental status and perspectives. In chapter 6 we assume that the reader to be acquainted with the theoretical motivations for SUSY and move directly to the direct search for dark matter and the description of the principal detector techniques: scintillators, noble fluids and bolometers. We conclude with an outlook on the future perspectives.

  20. Radiative light dark matter

    Science.gov (United States)

    Dedes, A.; Karamitros, D.; Pilaftsis, A.

    2017-06-01

    We present a Peccei-Quinn (PQ)-symmetric two-Higgs doublet model that naturally predicts a fermionic singlet dark matter in the mass range 10 keV-1 GeV. The origin of the smallness of the mass of this light singlet fermion arises predominantly at the one-loop level, upon soft or spontaneous breakdown of the PQ symmetry via a complex scalar field in a fashion similar to the so-called Dine-Fischler-Sredniki-Zhitnitsky axion model. The mass generation of this fermionic radiative light dark matter (RLDM) requires the existence of two heavy vectorlike SU(2) isodoublets, which are not charged under the PQ symmetry. We show how the RLDM can be produced via the freeze-in mechanism, thus accounting for the missing matter in the Universe. Finally, we briefly discuss possible theoretical and phenomenological implications of the RLDM model for the strong C P problem and the CERN Large Hadron Collider (LHC).

  1. Subjective Vitality as Mediator and Moderator of the Relationship between Life Satisfaction and Subjective Happiness

    Science.gov (United States)

    Uysal, Recep; Satici, Seydi Ahmet; Satici, Begüm; Akin, Ahmet

    2014-01-01

    In this study, the mediator and moderator effects of subjective vitality on the relationship between life satisfaction and subjective happiness were investigated. The participants were 378 university students who completed a questionnaire package that included the Subjective Vitality Scale, the Satisfaction with Life Scale, and the Subjective…

  2. Nanostructured Soft Matter Experiment, Theory, Simulation and Perspectives

    CERN Document Server

    Zvelindovsky, Andrei V

    2007-01-01

    This book provides an interdisciplinary overview of a new and broad class of materials under the unifying name Nanostructured Soft Matter. It covers materials ranging from short amphiphilic molecules to block copolymers, proteins, colloids and their composites, microemulsions and bio-inspired systems such as vesicles. The book considers several fundamental questions, including: how self-assembly of various soft materials with internal structure at the nanoscale can be understood, controlled and in future used in the newly emerging field of soft nanotechnology. The book offers readers a view on the subject from different perspectives, combining modern experimental approaches from physical chemistry and physics with various theoretical techniques from physics, mathematics and the most advanced computer modelling. It is the first book of this sort in the field. All chapters are written by leading international experts, bringing together experience from Canada, Germany, Great Britain, Japan, the Netherlands, Russ...

  3. Automated measurement of local white matter lesion volume

    DEFF Research Database (Denmark)

    van der Lijn, Fedde; Verhaaren, Benjamin F. J.; Ikram, M. Arfan

    2012-01-01

    It has been hypothesized that white matter lesions at different locations may have different etiology and clinical consequences. Several approaches for the quantification of local white matter lesion load have been proposed in the literature, most of which rely on a distinction between lesions...... in a periventricular region close to the ventricles and a subcortical zone further away. In this work we present a novel automated method for local white matter lesion volume quantification in magnetic resonance images. The method segments and measures the white matter lesion volume in 43 regions defined...... by orientation and distance to the ventricles, which allows a more spatially detailed study of lesion load. The potential of the method was demonstrated by analyzing the effect of blood pressure on the regional white matter lesion volume in 490 elderly subjects taken from a longitudinal population study...

  4. Yes, research matters.

    Directory of Open Access Journals (Sweden)

    Mari L Shinohara

    2017-08-01

    Full Text Available My father was diagnosed with stomach cancer recently. Luckily, it was still at an early stage, and endoscopic surgery successfully took care of it. My father was fortunate; since people with stomach cancer do not show clear symptoms in the early stages, the disease is often not diagnosed until it becomes advanced. In his case, the diagnosis started from a suggestion by his doctor to check whether he had a gastric infection with Helicobacter pylori, a bacterial species found in the digestive tract. In Japan, where he lives, a majority of gastric cancer patients (more than 99% have been infected with H. pylori [1], and the causative role of this bacterial species in promoting gastric cancer is very well established. Now, scientific understanding connecting gastric cancer to H. pylori is saving the lives of many people, including my father. Thinking about this recent personal experience, I wonder if the connection between bacteria and cancer might have been considered a crazy idea decades ago. Research makes it possible to connect seemingly unrelated matters. My laboratory works on seemingly unrelated research topics, such as fungal infections and autoimmunity. However, my question is the same whatever the topic: How do leukocytes elicit and regulate inflammation when they detect infections or endogenous signals? In fact, host receptors detecting pathogens can induce autoimmunity, and autoimmunity alters host sensitivity to pathogens due to the imbalance in the immune system. We are beginning to gain some insight into this question, as revealed by some of our recent studies. For example, the NLR family, pyrin domain containing 3 (NLRP3 inflammasome, which is known to sense a wide variety of pathogens, can also change the course of experimental autoimmune encephalomyelitis (EAE, an animal model of multiple sclerosis (MS. In particular, our study suggested that disease treatment approaches need to be changed based on the activation status of the NLRP

  5. Yes, research matters.

    Science.gov (United States)

    Shinohara, Mari L

    2017-08-01

    My father was diagnosed with stomach cancer recently. Luckily, it was still at an early stage, and endoscopic surgery successfully took care of it. My father was fortunate; since people with stomach cancer do not show clear symptoms in the early stages, the disease is often not diagnosed until it becomes advanced. In his case, the diagnosis started from a suggestion by his doctor to check whether he had a gastric infection with Helicobacter pylori, a bacterial species found in the digestive tract. In Japan, where he lives, a majority of gastric cancer patients (more than 99%) have been infected with H. pylori [1], and the causative role of this bacterial species in promoting gastric cancer is very well established. Now, scientific understanding connecting gastric cancer to H. pylori is saving the lives of many people, including my father. Thinking about this recent personal experience, I wonder if the connection between bacteria and cancer might have been considered a crazy idea decades ago. Research makes it possible to connect seemingly unrelated matters. My laboratory works on seemingly unrelated research topics, such as fungal infections and autoimmunity. However, my question is the same whatever the topic: How do leukocytes elicit and regulate inflammation when they detect infections or endogenous signals? In fact, host receptors detecting pathogens can induce autoimmunity, and autoimmunity alters host sensitivity to pathogens due to the imbalance in the immune system. We are beginning to gain some insight into this question, as revealed by some of our recent studies. For example, the NLR family, pyrin domain containing 3 (NLRP3) inflammasome, which is known to sense a wide variety of pathogens, can also change the course of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). In particular, our study suggested that disease treatment approaches need to be changed based on the activation status of the NLRP3 inflammasome

  6. Paying Hypertension Research Subjects

    Science.gov (United States)

    Casarett, David; Karlawish, Jason; Asch, David A

    2002-01-01

    CONTEXT Cash payments are often used to compensate subjects who participate in research. However, ethicists have argued that these payments might constitute an undue inducement. OBJECTIVES To determine whether potential subjects agree with theoretical arguments that a payment could be an undue inducement. DESIGN/SETTING/PARTICIPANTS Survey of 350 prospective jurors. MAIN OUTCOME MEASURES Belief that a $500 payment for research participation would impair their own, and others' ability to think carefully about the risks and benefits of a clinical trial. RESULTS Two hundred sixty-one jurors (74.6%) believed that a $500 payment would impair subjects' ability to think carefully about the risks and benefits of research. Ninety-six of 120 (80%) expressed this concern about subjects with a low income ($50,000). In contrast, only 69 (19.7%) of jurors believed that a $500 payment would influence them. Jurors who believed that this payment would influence them reported lower incomes and less education. CONCLUSION Members of the general public share ethical concerns about the influence of payments for research, although they believe that these concerns are more applicable to others than to themselves.

  7. Subjective Duration and Psychophysics

    Science.gov (United States)

    Eisler, Hannes

    1975-01-01

    Three models are proposed to describe the strategy applied by a subject when he is confronted with two successive time intervals and is required to deal with some relation between them, for example, by telling which was the longer by adjusting the second to match the first. (Author)

  8. Vector SIMP dark matter

    Science.gov (United States)

    Choi, Soo-Min; Hochberg, Yonit; Kuflik, Eric; Lee, Hyun Min; Mambrini, Yann; Murayama, Hitoshi; Pierre, Mathias

    2017-10-01

    Strongly Interacting Massive Particles (SIMPs) have recently been proposed as light thermal dark matter relics. Here we consider an explicit realization of the SIMP mechanism in the form of vector SIMPs arising from an SU(2) X hidden gauge theory, where the accidental custodial symmetry protects the stability of the dark matter. We propose several ways of equilibrating the dark and visible sectors in this setup. In particular, we show that a light dark Higgs portal can maintain thermal equilibrium between the two sectors, as can a massive dark vector portal with its generalized Chern-Simons couplings to the vector SIMPs, all while remaining consistent with experimental constraints.

  9. 40 CFR 60.1400 - What must I include in my initial report?

    Science.gov (United States)

    2010-07-01

    ... particulate matter control device. (b) The results of the initial stack tests for eight pollutants or.... (3) Lead. (4) Mercury. (5) Opacity. (6) Particulate matter. (7) Hydrogen chloride. (8) Fugitive ash. (c) The test report that documents the initial stack tests including supporting calculations. (d) The...

  10. Thin films of soft matter

    CERN Document Server

    Kalliadasis, Serafim

    2007-01-01

    A detailed overview and comprehensive analysis of the main theoretical and experimental advances on free surface thin film and jet flows of soft matter is given. At the theoretical front the book outlines the basic equations and boundary conditions and the derivation of low-dimensional models for the evolution of the free surface. Such models include long-wave expansions and equations of the boundary layer type and are analyzed via linear stability analysis, weakly nonlinear theories and strongly nonlinear analysis including construction of stationary periodic and solitary wave and similarity solutions. At the experimental front a variety of very recent experimental developments is outlined and the link between theory and experiments is illustrated. Such experiments include spreading drops and bubbles, imbibitions, singularity formation at interfaces and experimental characterization of thin films using atomic force microscopy, ellipsometry and contact angle measurements and analysis of patterns using Minkows...

  11. A smartphone application for earthquakes that matter!

    Science.gov (United States)

    Bossu, Rémy; Etivant, Caroline; Roussel, Fréderic; Mazet-Roux, Gilles; Steed, Robert

    2014-05-01

    level of shaking intensity with empirical models of fatality losses calibrated on past earthquakes in each country. Non-seismic detections and macroseismic questionnaires collected online are combined to identify as many as possible of the felt earthquakes regardless their magnitude. Non seismic detections include Twitter earthquake detections, developed by the US Geological Survey, where the number of tweets containing the keyword "earthquake" is monitored in real time and flashsourcing, developed by the EMSC, which detect traffic surges on its rapid earthquake information website caused by the natural convergence of eyewitnesses who rush to the Internet to investigate the cause of the shaking that they have just felt. All together, we estimate that the number of detected felt earthquakes is around 1 000 per year, compared with the 35 000 earthquakes annually reported by the EMSC! Felt events are already the subject of the web page "Latest significant earthquakes" on EMSC website (http://www.emsc-csem.org/Earthquake/significant_earthquakes.php) and of a dedicated Twitter service @LastQuake. We will present the identification process of the earthquakes that matter, the smartphone application itself (to be released in May) and its future evolutions.

  12. TASI Lectures on Indirect Detection of Dark Matter

    OpenAIRE

    Slatyer, Tracy R.

    2017-01-01

    These lectures, presented at TASI 2016: Anticipating the Next Discoveries in Particle Physics, provide an introduction to some key methods and tools of indirect dark matter searches. Topics covered include estimation of dark matter signals, thermal freezeout and related scenarios, potential effects of dark matter annihilation on the early universe, modeling photon signals from annihilation or decay, and a brief and qualitative introduction to diffusive propagation of cosmic rays. The second h...

  13. Many-body theory of nuclear and neutron star matter

    Energy Technology Data Exchange (ETDEWEB)

    Pandharipande, V.R.; Akmal, A.; Ravenhall, D.G. [Dept. of Physics, Univ. of Illinois at Urbana-Champaign, Urbana, IL (United States)

    1998-06-01

    We present results obtained for nuclei, nuclear and neutron star matter, and neutron star structure obtained with the recent Argonne v{sub 18} two- nucleon and Urbana IX three-nucleon interactions including relativistic boost corrections. These interactions predict that matter will undergo a transition to a spin layered phase with neutral pion condensation. We also consider the possibility of a transition to quark matter. (orig.)

  14. White Matter Development in Adolescence: A DTI Study

    OpenAIRE

    Asato, M. R.; Terwilliger, R.; Woo, J.; B. Luna

    2010-01-01

    Adolescence is a unique period of physical and cognitive development that includes concurrent pubertal changes and sex-based vulnerabilities. While diffusion tensor imaging (DTI) studies show white matter maturation throughout the lifespan, the state of white matter integrity specific to adolescence is not well understood as are the contributions of puberty and sex. We performed whole-brain DTI studies of 114 children, adolescents, and adults to identify age-related changes in white matter in...

  15. Towards the next generation of simplified Dark Matter models

    Science.gov (United States)

    Albert, Andreas; Bauer, Martin; Brooke, Jim; Buchmueller, Oliver; Cerdeño, David G.; Citron, Matthew; Davies, Gavin; de Cosa, Annapaola; De Roeck, Albert; De Simone, Andrea; Du Pree, Tristan; Flaecher, Henning; Fairbairn, Malcolm; Ellis, John; Grohsjean, Alexander; Hahn, Kristian; Haisch, Ulrich; Harris, Philip C.; Khoze, Valentin V.; Landsberg, Greg; McCabe, Christopher; Penning, Bjoern; Sanz, Veronica; Schwanenberger, Christian; Scott, Pat; Wardle, Nicholas

    2017-06-01

    This White Paper is an input to the ongoing discussion about the extension and refinement of simplified Dark Matter (DM) models. It is not intended as a comprehensive review of the discussed subjects, but instead summarises ideas and concepts arising from a brainstorming workshop that can be useful when defining the next generation of simplified DM models (SDMM). In this spirit, based on two concrete examples, we show how existing SDMM can be extended to provide a more accurate and comprehensive framework to interpret and characterise collider searches. In the first example we extend the canonical SDMM with a scalar mediator to include mixing with the Higgs boson. We show that this approach not only provides a better description of the underlying kinematic properties that a complete model would possess, but also offers the option of using this more realistic class of scalar mixing models to compare and combine consistently searches based on different experimental signatures. The second example outlines how a new physics signal observed in a visible channel can be connected to DM by extending a simplified model including effective couplings. In the next part of the White Paper we outline other interesting options for SDMM that could be studied in more detail in the future. Finally, we review important aspects of supersymmetric models for DM and use them to propose how to develop more complete SDMMs. This White Paper is a summary of the brainstorming meeting ;Next generation of simplified Dark Matter models; that took place at Imperial College, London on May 6, 2016, and corresponding follow-up studies on selected subjects.

  16. An Optimized Clustering Approach for Automated Detection of White Matter Lesions in MRI Brain Images

    Directory of Open Access Journals (Sweden)

    M. Anitha

    2012-04-01

    Full Text Available Settings White Matter lesions (WMLs are small areas of dead cells found in parts of the brain. In general, it is difficult for medical experts to accurately quantify the WMLs due to decreased contrast between White Matter (WM and Grey Matter (GM. The aim of this paper is to
    automatically detect the White Matter Lesions which is present in the brains of elderly people. WML detection process includes the following stages: 1. Image preprocessing, 2. Clustering (Fuzzy c-means clustering, Geostatistical Possibilistic clustering and Geostatistical Fuzzy clustering and 3.Optimization using Particle Swarm Optimization (PSO. The proposed system is tested on a database of 208 MRI images. GFCM yields high sensitivity of 89%, specificity of 94% and overall accuracy of 93% over FCM and GPC. The clustered brain images are then subjected to Particle Swarm Optimization (PSO. The optimized result obtained from GFCM-PSO provides sensitivity of 90%, specificity of 94% and accuracy of 95%. The detection results reveals that GFCM and GFCMPSO better localizes the large regions of lesions and gives less false positive rate when compared to GPC and GPC-PSO which captures the largest loads of WMLs only in the upper ventral horns of the brain.

  17. Sex differences in white matter development during adolescence: a DTI study.

    Science.gov (United States)

    Wang, Yingying; Adamson, Chris; Yuan, Weihong; Altaye, Mekibib; Rajagopal, Akila; Byars, Anna W; Holland, Scott K

    2012-10-10

    Adolescence is a complex transitional period in human development, composing physical maturation, cognitive and social behavioral changes. The objective of this study is to investigate sex differences in white matter development and the associations between intelligence and white matter microstructure in the adolescent brain using diffusion tensor imaging (DTI) and tract-based spatial statistics (TBSS). In a cohort of 16 typically-developing adolescents aged 13 to 17 years, longitudinal DTI data were recorded from each subject at two time points that were one year apart. We used TBSS to analyze the diffusion indices including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD). Our results suggest that boys (13-18 years) continued to demonstrate white matter maturation, whereas girls appeared to reach mature levels earlier. In addition, we identified significant positive correlations between FA and full-scale intelligence quotient (IQ) in the right inferior fronto-occipital fasciculus when both sexes were looked at together. Only girls showed significant positive correlations between FA and verbal IQ in the left cortico-spinal tract and superior longitudinal fasciculus. The preliminary evidence presented in this study supports that boys and girls have different developmental trajectories in white matter microstructure. Copyright © 2012 Elsevier B.V. All rights reserved.

  18. Gray Matter Concentration Abnormality in Brains of Narcolepsy Patients

    Energy Technology Data Exchange (ETDEWEB)

    Joo, Eun Yeon; Tae, Woo Suk; Kim, Sung Tae; Hong, Seung Bong [Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2009-12-15

    To investigate gray matter concentration changes in the brains of narcoleptic patients. Twenty-nine narcoleptic patient with cataplexy and 29 age and sex-matched normal subjects (mean age, 31 years old) underwent volumetric MRIs. The MRIs were spatially normalized to a standard T1 template and subdivided into gray matter, white matter, and cerebrospinal fluid (CSF). These segmented images were then smoothed using a 12-mm full width at half maximum (FWHM) isotropic Gaussian kernel. An optimized voxel-based morphometry protocol was used to analyze brain tissue concentrations using SPM2 (statistical parametric mapping). A one-way analysis of variance was applied to the concentration analysis of gray matter images. Narcoleptics with cataplexy showed reduced gray matter concentration in bilateral thalami, left gyrus rectus, bilateral frontopolar gyri, bilateral short insular gyri, bilateral superior frontal gyri, and right superior temporal and left inferior temporal gyri compared to normal subjects (uncorrected p < 0.001). Furthermore, small volume correction revealed gray matter concentration reduction in bilateral nuclei accumbens, hypothalami, and thalami (false discovery rate corrected p < 0.05). Gray matter concentration reductions were observed in brain regions related to excessive daytime sleepiness, cognition, attention, and memory in narcoleptics with cataplexy

  19. Strongly interacting matter in magnetic fields

    CERN Document Server

    Landsteiner, Karl; Schmitt, Andreas; Yee, Ho-Ung

    2013-01-01

    The physics of strongly interacting matter in an external magnetic field is presently emerging as a topic of great cross-disciplinary interest for particle, nuclear, astro- and condensed matter physicists. It is known that strong magnetic fields are created in heavy ion collisions, an insight that has made it possible to study a variety of surprising and intriguing phenomena that emerge from the interplay of quantum anomalies, the topology of non-Abelian gauge fields, and the magnetic field. In particular, the non-trivial topological configurations of the gluon field induce a non-dissipative electric current in the presence of a magnetic field. These phenomena have led to an extended formulation of relativistic hydrodynamics, called chiral magnetohydrodynamics. Hitherto unexpected applications in condensed matter physics include graphene and topological insulators. Other fields of application include astrophysics, where strong magnetic fields exist in magnetars and pulsars. Last but not least, an important ne...

  20. Native language influence on the distributive effect in producing second language subject-verb agreement.

    Science.gov (United States)

    Wei, Xiaoyan; Chen, Baoguo; Liang, Lijuan; Dunlap, Susan

    2015-01-01

    Three experiments were conducted to investigate the distributive effect when producing subject-verb agreement in English as a second language (L2) when the participant's first language either does or does not require subject-verb agreement. Both Chinese-English and Uygur-English bilinguals were included in Experiment 1. Chinese has no required subject-verb agreement, whereas Uygur does. Results showed that the distributive effect was observed in Uygur-English bilinguals but not in Chinese-English bilinguals, indicating that this particular first language (L1) syntactic feature is one significant factor affecting the distributive effect in the production of subject-verb agreement in L2. Experiment 2 further investigated the matter by choosing Chinese-English participants with higher L2 proficiency. Still, no distributive effect was observed, suggesting that the absence of distributive effect in Chinese-English bilinguals in Experiment 1 was not due to low proficiency in the target language. Experiment 3 changed the way the stimuli were presented, highlighting the singular or distributive nature of the subject noun phrases, and the distributive effect was observed in Chinese-English bilinguals. Altogether, the results show that the L1 syntactic feature of subject-verb agreement is one significant factor affecting the distributive effect in the production of subject-verb agreement in L2. More specifically, distributive effects rarely occur in L2 when L1 has no requirement on subject-verb agreement, whereas distributive effects are more likely to occur in L2 when the L1 also has required subject-verb agreement.

  1. Objective and subjective sleep quality

    DEFF Research Database (Denmark)

    Baandrup, Lone; Glenthøj, Birte Yding; Jennum, Poul Jørgen

    2016-01-01

    and subjective sleep quality during benzodiazepine discontinuation and whether sleep variables were associated with benzodiazepine withdrawal. Eligible patients included adults with a diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder and long-term use of benzodiazepines in combination...... with antipsychotics. All participants gradually tapered the use of benzodiazepines after randomization to add-on treatment with melatonin versus placebo. Here we report a subsample of 23 patients undergoing sleep recordings (one-night polysomnography) and 55 patients participating in subjective sleep quality ratings....... Melatonin had no effect on objective sleep efficiency, but significantly improved self-reported sleep quality. Reduced benzodiazepine dosage at the 24-week follow-up was associated with a significantly decreased proportion of stage 2 sleep. These results indicate that prolonged-release melatonin has some...

  2. Electrons in Condensed Matter

    Indian Academy of Sciences (India)

    entire liquid or solid. The variety of electronic behaviour which ... sity of electronic behaviour in condensed matter, ego ferro- ..... a big dog? We do not know the reasons yet. As it turns out for many fundamentally interesting phenomena, colossal magneto- resistance may also find applications, this time in magnetic recording.

  3. Dichromatic dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Bai, Yang; Su, Meng; Zhao, Yue

    2013-02-01

    Both the robust INTEGRAL 511 keV gamma-ray line and the recent tentative hint of the 135 GeV gamma-ray line from Fermi-LAT have similar signal morphologies, and may be produced from the same dark matter annihilation. Motivated by this observation, we construct a dark matter model to explain both signals and to accommodate the two required annihilation cross sections that are different by more than six orders of magnitude. In our model, to generate the low-energy positrons for INTEGRAL, dark matter particles annihilate into a complex scalar that couples to photon via a charge-radius operator. The complex scalar contains an excited state decaying into the ground state plus an off-shell photon to generate a pair of positron and electron. Two charged particles with non-degenerate masses are necessary for generating this charge-radius operator. One charged particle is predicted to be long-lived and have a mass around 3.8 TeV to explain the dark matter thermal relic abundance from its late decay. The other charged particle is predicted to have a mass below 1 TeV given the ratio of the two signal cross sections. The 14 TeV LHC will concretely test the main parameter space of this lighter charged particle.

  4. Electrons in Condensed Matter

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 12. Electrons in Condensed Matter. T V Ramakrishnan. General Article Volume 2 Issue 12 December 1997 pp 17-32. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/002/12/0017-0032 ...

  5. Anti-matter factory

    CERN Document Server

    Michaut, C

    2003-01-01

    In 1928 Paul Dirac predicted the existence of anti-matter as a consequence of his theory. The first experimental fact that supported this idea was the discovery of the positron in 1932. Anti-protons were produced in 1955 at the Bevatron facility in Berkeley and anti-neutrons the following year. Since 1964 scientists know that matter and anti-matter differ not only from their electrical charge but also from their behaviour concerning weak interaction. In 2002 the CERN announced the production of more than 50.000 atoms of anti-hydrogen which was a breakthrough because the last attempt in 1995 ended with the creation of only 9 atoms of anti-hydrogen whose speed neared the velocity of light while the speed of the last ones created is 100.000 times smaller. The next step is to carry out experiments in order to measure the spectra of anti-hydrogen in a very accurate manner and to test the effect of gravity on anti-matter. (A.C.)

  6. Template Composite Dark Matter

    DEFF Research Database (Denmark)

    Drach, Vincent; Hietanen, Ari; Pica, Claudio

    2015-01-01

    We present a non perturbative study of SU(2) gauge theory with two fundamental Dirac flavours. We discuss how the model can be used as a template for composite Dark Matter (DM). We estimate one particular interaction of the DM candidate with the Standard Model : the interaction through photon...

  7. The Dark Matter Problem

    NARCIS (Netherlands)

    Sanders, Robert H.

    1. Introduction; 2. Early history of the dark matter hypothesis; 3. The stability of disk galaxies: the dark halo solutions; 4. Direct evidence: extended rotation curves of spiral galaxies; 5. The maximum disk: light traces mass; 6. Cosmology and the birth of astroparticle physics; 7. Clusters

  8. Solitons in nuclear matter

    Energy Technology Data Exchange (ETDEWEB)

    Kurilkin, N.N.; Mishustin, I.N.; Khodel' , V.A.

    1979-10-05

    The propagation of finite-amplitude waves in cold nuclear matter is investigated. It is shown that by taking into account the nonlinear terms in the equations for the Fermi-liquid theory, we obtain elongated wave-soliton-type solutions.

  9. A triangle that matters

    CERN Multimedia

    Gershon, Tim

    2007-01-01

    "Physicists at "B-factories" in the US and Japan are closing in on an abstract diagram called the unitarity triangle in the quest to explain the difference between matter and antimatter. But such measurements could also point the way to the discovery of new fundamental particles." (5 pages)

  10. The Birth of Matter

    CERN Multimedia

    2005-01-01

    To mark the World Year of Physics, the Physics Section of the University of Geneva is organising a series of lectures for the uninitiated. Each lecture will begin with a demonstration in the auditorium of the detection of cosmic rays and, in collaboration with Professor E. Ellberger of the Conservatoire de Musique de Genève, of how these signals from the farthest reaches of the Universe can be used to create "cosmic music". The fourth lecture in the series, entitled "The Birth of Matter", will take place on Tuesday 3 May 2005 and will be given by CERN's theoretical physicist, John Ellis. Where does matter come from? Where do the structures that surround us, such as galaxies, come from? Are we living in a world of invisible matter? Why is the universe so old and so big? John Ellis will show how elementary particle physics and, in particular, the LHC under construction at CERN, can answer these questions. The Birth of Matter Professor John Ellis Tuesday 3 May, starting 8.00 p.m. Main Audito...

  11. The Birth of Matter

    CERN Multimedia

    2005-01-01

    To mark the World Year of Physics, the Physics Section of the University of Geneva is organising a series of lectures for the uninitiated. Each lecture will begin with a demonstration in the auditorium of the detection of cosmic rays and, in collaboration with Professor E. Ellberger of the Conservatoire de Musique de Genève, of how these signals from the farthest reaches of the Universe can be used to create 'cosmic music'. The fourth lecture in the series, entitled 'The Birth of Matter', will take place on Tuesday 3 May 2005 and will be given by CERN's theoretical physicist, John Ellis. Where does matter come from? Where do the structures that surround us, such as galaxies, come from? Are we living in a world of invisible matter? Why is the universe so old and so big? John Ellis will show how elementary particle physics and, in particular, the LHC under construction at CERN, can answer these questions. The Birth of Matter Professor John Ellis Tuesday 3 May, starting 8.00 p.m. Main Auditorium...

  12. White matter lesion progression

    DEFF Research Database (Denmark)

    Hofer, Edith; Cavalieri, Margherita; Bis, Joshua C

    2015-01-01

    BACKGROUND AND PURPOSE: White matter lesion (WML) progression on magnetic resonance imaging is related to cognitive decline and stroke, but its determinants besides baseline WML burden are largely unknown. Here, we estimated heritability of WML progression, and sought common genetic variants asso...

  13. Energy Matters - Spring 2002

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-03-01

    Quarterly newsletter from DOE's Industrial Technologies Program to promote the use of energy-efficient industrial systems. The focus of the Spring 2002 Issue of Energy Matters focuses on premium energy efficiency systems, with articles on new gas technologies, steam efficiency, the Augusta Newsprint Showcase, and more.

  14. Condensed-Matter Physics.

    Science.gov (United States)

    Hirsch, Jorge E.; Scalapino, Douglas J.

    1983-01-01

    Discusses ways computers are being used in condensed-matter physics by experimenters and theorists. Experimenters use them to control experiments and to gather and analyze data. Theorists use them for detailed predictions based on realistic models and for studies on systems not realizable in practice. (JN)

  15. Exotic nuclear matter

    Directory of Open Access Journals (Sweden)

    Lenske H.

    2016-01-01

    Full Text Available Recent developments of nuclear structure theory for exotic nuclei are addressed. The inclusion of hyperons and nucleon resonances is discussed. Nuclear multipole response functions, hyperon interactions in infinite matter and in neutron stars and theoretical aspects of excitations of nucleon resonances in nuclei are discussed.

  16. States of Matter

    Indian Academy of Sciences (India)

    if the matter being taught is correct or incorrect. And if it is correct, to what .... 2, in some units. This will be an unnatural and artificial definition. (Why this value?). Artificial and unnatural definitions are not useful, as there is a good chance somebody else will choose a ... you make an arbitrary definition, it is unlikely to be use-.

  17. Matter: the fundamental particles

    CERN Multimedia

    Landua, Rolf

    2007-01-01

    "The largest particle physics centre in the world is located in Europe. It straddles the Franco-Swiss border, near Geneva. At CERN - the European Organisation for Nuclear Research , which is focused on the science of nuclear matter rather than on the exploitation of atomic energy - there are over 6 500 scientists." (1 page)

  18. Hot nuclear matter

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, Scott [Univ. of California, Berkeley, CA (United States)

    1992-11-01

    The goal in this thesis is thus twofold: The first is to investigate the feasibility of using heavy ion collisions to create conditions in the laboratory which are ripe for the formation of a quark-gluon plasma. The second is to develop a technique for studying some of the many non-perturbative features of this novel phase of matter.

  19. Resources: Money Matters.

    Science.gov (United States)

    Woodard, Dudley B., Jr.; Love, Patrick; Komives, Susan R.

    2000-01-01

    Fiscal concerns continue to challenge institutions of higher learning and will affect the financing of student services initiatives. By being aware of current fiscal trends, critiquing thinking about financial matters, and attempting to find new sources of revenue for the future, student affairs practitioners will be able to anticipate and address…

  20. Exceptional composite dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Ballesteros, Guillermo [Universite Paris Saclay, CEA, CNRS, Institut de Physique Theorique, Gif-sur-Yvette (France); Carmona, Adrian [CERN, Theoretical Physics Department, Geneva (Switzerland); Chala, Mikael [Universitat de Valencia y IFIC, Universitat de Valencia-CSIC, Departament de Fisica Teorica, Burjassot, Valencia (Spain)

    2017-07-15

    We study the dark matter phenomenology of non-minimal composite Higgs models with SO(7) broken to the exceptional group G{sub 2}. In addition to the Higgs, three pseudo-Nambu-Goldstone bosons arise, one of which is electrically neutral. A parity symmetry is enough to ensure this resonance is stable. In fact, if the breaking of the Goldstone symmetry is driven by the fermion sector, this Z{sub 2} symmetry is automatically unbroken in the electroweak phase. In this case, the relic density, as well as the expected indirect, direct and collider signals are then uniquely determined by the value of the compositeness scale, f. Current experimental bounds allow one to account for a large fraction of the dark matter of the Universe if the dark matter particle is part of an electroweak triplet. The totality of the relic abundance can be accommodated if instead this particle is a composite singlet. In both cases, the scale f and the dark matter mass are of the order of a few TeV. (orig.)