Better Renal Resistive Index Profile in Subjects with Beta Thalassemia Minor .

Science.gov (United States)

Basut, Fahrettin; Keşkek, Şakir Özgür; Gülek, Bozkurt

2018-05-03

Beta thalassaemia minor is a common genetic disorder without any characteristic symptoms except mild anemia. It is found to be associated with some cardiovascular risk factors such as insulin resistance and diabetes mellitus. The renal resistive index (RRI) is a measure of renal arterial resistance to blood flow. The aim of this study was to evaluate the renal resistive index in subjects with beta thalassaemia minor (BTM). A total of 253 subjects were included in this cross-sectional study. The study group consisted of 148 subjects with BTM and the control group consisted of 105 healthy subjects. Beta thalassaemia minor was diagnosed by complete blood count and hemoglobin electrophoresis. Blood pressure measurement and biochemical tests were performed. Renal resistive index of all subjects was measured using renal Doppler ultrasonography. Subjects with beta thalassemia minor had lower renal resistive indices compared to healthy subjects (0.58 ± 0.04 vs. 0.60 ± 0.06, p = 0.0016). Additionally, the RRI levels of subjects with BTM were correlated with systolic blood pressure (p = 0.017, r = 0.194). In this study, lower renal resistive index was found in subjects with BTM. This may be associated with decreased vascular resistance and blood viscosity in these subjects. ©2018The Author(s). Published by S. Karger AG, Basel.

The Lp_3561 and Lp_3562 enzymes support a functional divergence process in the lipase/esterase toolkit from Lactobacillus plantarum

Directory of Open Access Journals (Sweden)

Maria Esteban-Torres

2016-07-01

Full Text Available Lactobacillus plantarum species is a good source of esterases since both lipolytic and esterase activities have been described for strains of this species. No fundamental biochemical difference exists among esterases and lipases since both share a common catalytic mechanism. L. plantarum WCFS1 possesses a protein, Lp_3561, which is 44% identical to a previously described lipase, Lp_3562. In contrast to Lp_3562, Lp_3561 was unable to degrade esters possessing a chain length higher than C4 and the triglyceride tributyrin. As in other L. plantarum esterases, the electrostatic potential surface around the active site in Lp_3561 is predicted to be basic, whereas it is essentially neutral in the Lp_3562 lipase. The fact that the genes encoding both proteins were located contiguously in the L. plantarum WCFS1 genome, suggests that they originated by tandem duplication, and therefore are paralogs as new functions have arisen during evolution. The presence of the contiguous lp_3561 and lp_3562 genes was studied among L. plantarum strains. They are located in a 8,903 bp DNA fragment that encodes proteins involved in the catabolism of sialic acid and are predicted to increase bacterial adaptability under certain growth conditions.

78 FR 21491 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption...

Science.gov (United States)

2013-04-10

... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0662, 02/02-0661] DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P. and DeltaPoint...

A spinach O-acetylserine(thiollyase homologue, SoCSaseLP, suppresses cysteine biosynthesis catalysed by other enzyme isoforms

Directory of Open Access Journals (Sweden)

Miki Noda

2016-06-01

Full Text Available An enzyme, O-acetylserine(thiollyase (OASTL, also known as O-acetylserine sulfhydrylase or cysteine synthase (CSase, catalyses the incorporation of sulfide into O-acetylserine and produces cysteine. We previously identified a cDNA encoding an OASTL-like protein from Spinacia oleracea, (SoCSaseLP, but a recombinant SoCSaseLP produced in Escherichia coli did not show OASTL activity. The exon-intron structure of the SoCSaseLP gene shared conserved structures with other spinach OASTL genes. The SoCSaseLP and a Beta vulgaris homologue protein, KMT13462, comprise a unique clade in the phylogenetic tree of the OASTL family. Interestingly, when the SoCSaseLP gene was expressed in tobacco plants, total OASTL activity in tobacco leaves was reduced. This reduction in total OASTL activity was most likely caused by interference by SoCSaseLP with cytosolic OASTL. To investigate the possible interaction of SoCSaseLP with a spinach cytosolic OASTL isoform SoCSaseA, a pull-down assay was carried out. The recombinant glutathione S-transferase (GST-SoCSaseLP fusion protein was expressed in E. coli together with the histidine-tagged SoCSaseA protein, and the protein extract was subjected to glutathione affinity chromatography. The histidine-tagged SoCSaseA was co-purified with the GST-SoCSaseLP fusion protein, indicating the binding of SoCSaseLP to SoCSaseA. Consistent with this interaction, the OASTL activity of the co-purified SoCSaseA was reduced compared with the activity of SoCSaseA that was purified on its own. These results strongly suggest that SoCSaseLP negatively regulates the activity of other cytosolic OASTL family members by direct interaction.

West Africa LP gas market development study

International Nuclear Information System (INIS)

2001-01-01

Jointly sponsored with the World Bank, this essential study explores the opportunity for greatly expanded LP Gas use in the West Africa region. LP Gas supply in the area is increasing rapidly, This offers the opportunity for bringing modern energy to millions without current access, protects forests the only current source of energy for many, and encourages governments to adopt proactive policies that will reap benefits of the increasing availability of LP Gas. (author)

Chemical evolution and the origin of life: cumulative keyword subject index 1970-1986

Science.gov (United States)

Roy, A. C.; Powers, J. V.; Rummel, J. D. (Principal Investigator)

1990-01-01

This cumulative subject index encompasses the subject indexes of the bibliographies on Chemical Evolution and the Origin of Life that were first published in 1970 and have continued through publication of the 1986 bibliography supplement. Early bibliographies focused on experimental and theoretical material dealing directly with the concepts of chemical evolution and the origin of life, excluding the broader areas of exobiology, biological evolution, and geochemistry. In recent years, these broader subject areas have also been incorporated as they appear in literature searches relating to chemical evolution and the origin of life, although direct attempts have not been made to compile all of the citations in these broad areas. The keyword subject indexes have also undergone an analogous change in scope. Compilers of earlier bibliographies used the most specific term available in producing the subject index. Compilers of recent bibliographies have used a number of broad terms relating to the overall subject content of each citation and specific terms where appropriate. The subject indexes of these 17 bibliographies have, in general, been cumulatively compiled exactly as they originally appeared. However, some changes have been made in an attempt to correct errors, combine terms, and provide more meaningful terms.

Device orientation of a leadless pacemaker and subcutaneous implantable cardioverter-defibrillator in canine and human subjects and the effect on intrabody communication.

Science.gov (United States)

Quast, Anne-Floor B E; Tjong, Fleur V Y; Koop, Brendan E; Wilde, Arthur A M; Knops, Reinoud E; Burke, Martin C

2018-02-14

The development of communicating modular cardiac rhythm management systems relies on effective intrabody communication between a subcutaneous implantable cardioverter-defibrillator (S-ICD) and a leadless pacemaker (LP), using conducted communication. Communication success is affected by the LP and S-ICD orientation. This study is designed to evaluate the orientation of the LP and S-ICD in canine subjects and measure success and threshold of intrabody communication. To gain more human insights, we will explore device orientation in LP and S-ICD patients. Canine subjects implanted with a prototype S-ICD and LP (both Boston Scientific, MA, USA) with anterior-posterior fluoroscopy images were included in this analysis. For comparison, a retrospective analysis of human S-ICD and LP patients was performed. The angle of the long axis of the LP towards the vertical axis of 0°, and distance between the coil and LP were measured. Twenty-three canine subjects were analysed. Median angle of the LP was 29° and median distance of the S-ICD coil to LP was 0.8 cm. All canine subjects had successful communication. The median communicating threshold was 2.5 V. In the human retrospective analysis, 72 LP patients and 100 S-ICD patients were included. The mean angle of the LP was 56° and the median distance between the S-ICD coil and LP was 4.6 cm. Despite the less favourable LP orientation in canine subjects, all communication attempts were successful. In the human subjects, we observed a greater and in theory more favourable LP angle towards the communication vector. These data suggests suitability of human anatomy for conductive intrabody communication.

View of the LP gas supply/demand in Asia and a survey of the Middle East trend; Asia no LP gas jukyu tenbo to Chuto doko chosa

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-09-01

A study was made on the LP gas supply/demand in Asia including an outlook for 2000. Eleven countries in Asia including NIES countries, ASEAN countries, China and India have been continuing their rapid growth of economy and have rapidly been increasing their energy consumption. There, LP gas spreads as a home use fuel, and countries excluding some LP gas producing countries depend considerably upon the import from the Middle East. The LP gas consumption quantity is steadily increasing in China and India having huge population, etc., and dependence of LP gas is increasing upon LP gas producing countries of the Middle East. Nevertheless, in the Middle East, the domestic consumption of LP gas, mostly butane, is increasing. Namely, butane is used as raw material of MTBE, and LP gas as that of petroleum chemicals. The Middle East has a lot of plant projects of a sizable size in the future, which predicts that LP gas export from LP gas producing countries of the Middle East is decreasing. 2 refs., 62 figs., 57 tabs.

Research Studies Index. Authors and Subjects. Volume 1 through Volume 43 (1929-1975).

Science.gov (United States)

Drazan, Joseph, Comp.; Scott, Paula, Comp.

This volume contains author and subject indexes for volumes 1 through 43 (1929-1975) of "Research Studies," a scholarly, multi-disciplinary quarterly published at Washington State University. Each author index entry includes the title, volume, and inclusive pagination of the article. The subject index is a keyword-out-of-context…

LP formulation of asymmetric zero-sum stochastic games

KAUST Repository

Li, Lichun

2014-12-15

This paper provides an efficient linear programming (LP) formulation of asymmetric two player zero-sum stochastic games with finite horizon. In these stochastic games, only one player is informed of the state at each stage, and the transition law is only controlled by the informed player. Compared with the LP formulation of extensive stochastic games whose size grows polynomially with respect to the size of the state and the size of the uninformed player\\'s actions, our proposed LP formulation has its size to be linear with respect to the size of the state and the size of the uninformed player, and hence greatly reduces the computational complexity. A travelling inspector problem is used to demonstrate the efficiency of the proposed LP formulation.

LP formulation of asymmetric zero-sum stochastic games

KAUST Repository

Li, Lichun; Shamma, Jeff S.

2014-01-01

This paper provides an efficient linear programming (LP) formulation of asymmetric two player zero-sum stochastic games with finite horizon. In these stochastic games, only one player is informed of the state at each stage, and the transition law is only controlled by the informed player. Compared with the LP formulation of extensive stochastic games whose size grows polynomially with respect to the size of the state and the size of the uninformed player's actions, our proposed LP formulation has its size to be linear with respect to the size of the state and the size of the uninformed player, and hence greatly reduces the computational complexity. A travelling inspector problem is used to demonstrate the efficiency of the proposed LP formulation.

Flygtninge på langvarig starthjælp

DEFF Research Database (Denmark)

Johansen, Adam; Højland, Marianne; Hansen, Henning

Spørgeskema-, fokusgruppe- og interviewbaseret undersøgelse af personlige og sociale konsekvenser af familiers forsørgelse på starthjælp. Kvalitativ og kvantitativ undersøgelse af starthjælpens konsekvenser for flygtningefamilier med mere end 1 år på starthjælp...

Trigonometric bases for matrix weighted Lp-spaces

DEFF Research Database (Denmark)

Nielsen, Morten

2010-01-01

We give a complete characterization of 2π-periodic matrix weights W for which the vector-valued trigonometric system forms a Schauder basis for the matrix weighted space Lp(T;W). Then trigonometric quasi-greedy bases for Lp(T;W) are considered. Quasi-greedy bases are systems for which the simple...

Lysosomal enlargement and lysosomal membrane destabilisation in mussel digestive cells measured by an integrative index

International Nuclear Information System (INIS)

Izagirre, Urtzi; Marigomez, Ionan

2009-01-01

Lysosomal responses (enlargement and membrane destabilisation) in mussel digestive cells are well-known environmental stress biomarkers in pollution effects monitoring in marine ecosystems. Presently, in laboratory and field studies, both responses were measured separately (in terms of lysosomal volume density - Vv - and labilisation period -LP) and combined (lysosomal response index - LRI) in order to contribute to their understanding and to develop an index useful for decisions makers. LRI integrates Vv and LP, which are not necessarily dependent lysosomal responses. It is unbiased and more sensitive than Vv and LP alone and diminishes background due to confounding factors. LRI provides a simple numerical index (consensus reference = 0; critical threshold = 1) directly related to the pollution impact degree. Moreover, LRI can be represented in a way that allows the interpretation of lysosomal responses, which is useful for environmental scientists. - Lysosomal responses to pollutants measured by an integrative index.

S¯adhan¯a Vol. 28, 2003 Subject Index

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

Porous carbon. 335. Active-R ... Aluminium oxide. Controlled wear of vitrified abrasive materials .... Machining and metrology systems for free- form laser printer ... Subject Index. Flow and fracture ... Grain/interphase boundary sliding. Thermally ...

Anti-soluble liver antigen/liver-pancreas (SLA/LP) antibodies in pediatric patients with autoimmune hepatitis.

Science.gov (United States)

Vitozzi, Susana; Djilali-Saiah, Idriss; Lapierre, Pascal; Alvarez, Fernando

2002-12-01

Antibodies against soluble liver antigen/liver-pancreas (SLA/LP) have been associated with severe autoimmune hepatitis (AIH) and poor outcome, but most of these reports have focused on adult patients. The aim of this study was to assess the prevalence and clinical significance of anti-SLA/LP antibodies in a pediatric population with AIH. We developed a quantitative enzyme-linked immunoassay (ELISA), a Western blot (WB) and an immunoprecipitation assay (IPA) based on recombinant cDNA from activated Jurkat cells. The specificity of these tests was validated by testing 200 serum samples from healthy subjects, and from patients with liver and non-liver diseases. Anti-SLA/LP antibodies were found in patients with type 1 and type 2 AIH. The prevalence of these antibodies in patients with type 1 AIH was: 42% when tested by ELISA, 15% by WB and 50% by IPA. In patients with type 2 AIH, the prevalence rates were 42% by ELISA, 18% by WB and 44% by IPA. The mean titer values for anti-SLA/LP antibodies was significantly higher in type 2 AIH (1:1,300 +/- 339) than in type 1 AIH (1:600 +/- 71; p LKM1) and anti-liver cytosol type 1 (LC1) antibodies in sera. The presence of anti-SLA/LP showed a significant female preponderance in type 1 and 2 AIH patients (p = 0.0003 and p = 0.003, respectively), and was significantly correlated with a lower age at diagnosis (p = 0.05) in type 1 AIH patients. In conclusion, anti-SLA/LP antibodies in pediatric patients are associated with both type 1 and 2 AIH.

Meningococcal Serogroup B Bivalent rLP2086 Vaccine Elicits Broad and Robust Serum Bactericidal Responses in Healthy Adolescents

DEFF Research Database (Denmark)

Vesikari, Timo; Østergaard, Lars Jørgen; Diez-Domingo, Javier

2015-01-01

BACKGROUND: Neisseria meningitidis serogroup B (MnB) is a leading cause of invasive meningococcal disease in adolescents and young adults. A recombinant factor H binding protein (fHBP) vaccine (Trumenba(®); bivalent rLP2086) was recently approved in the United States in individuals aged 10-25 years....... Immunogenicity and safety of 2- or 3-dose schedules of bivalent rLP2086 were assessed in adolescents. METHODS: Healthy adolescents (11 to ... bactericidal antibody assay using human complement (hSBA). Safety assessments included local and systemic reactions and adverse events. RESULTS: Bivalent rLP2086 was immunogenic when administered as 2 or 3 doses; the most robust hSBA responses occurred with 3 doses. The proportion of subjects with hSBA titers...

Genetic invalidation of Lp-PLA2 as a therapeutic target

DEFF Research Database (Denmark)

Gregson, John M; Freitag, Daniel F; Surendran, Praveen

2017-01-01

AIMS: Darapladib, a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), has not reduced risk of cardiovascular disease outcomes in recent randomized trials. We aimed to test whether Lp-PLA2 enzyme activity is causally relevant to coronary heart disease. METHODS: In 72...... (Val379Ala (rs1051931)) in PLA2G7, the gene encoding Lp-PLA2. We supplemented de-novo genotyping with information on a further 45,823 coronary heart disease patients and 88,680 controls in publicly available databases and other previous studies. We conducted a systematic review of randomized trials...... to compare effects of darapladib treatment on soluble Lp-PLA2 activity, conventional cardiovascular risk factors, and coronary heart disease risk with corresponding effects of Lp-PLA2-lowering alleles. RESULTS: Lp-PLA2 activity was decreased by 64% (p = 2.4 × 10(-25)) with carriage of any of the four loss...

A randomized, phase 1/2 trial of the safety, tolerability, and immunogenicity of bivalent rLP2086 meningococcal B vaccine in healthy infants.

Science.gov (United States)

Martinon-Torres, Federico; Gimenez-Sanchez, Francisco; Bernaola-Iturbe, Enrique; Diez-Domingo, Javier; Jiang, Qin; Perez, John L

2014-09-08

Neisseria meningitidis serogroup B (MnB) is a major cause of invasive meningococcal disease in infants. A conserved, surface-exposed lipoprotein, LP2086 (a factor H-binding protein [fHBP]), is a promising MnB vaccine target. A bivalent, recombinant vaccine targeting the fHBP (rLP2086) of MnB was developed. This phase 1/2 clinical study was designed to assess the immunogenicity, safety, and tolerability of a 4-dose series of the rLP2086 vaccine at 20-, 60-, 120-, or 200-μg dose levels in vaccine-naive infants when given with routine childhood vaccines. The study was to consist of two phases: a single-blind sentinel phase and an open-label full enrollment phase. During the sentinel phase, randomization of subjects to the next higher dose was delayed pending a 14-day safety review of dose 1 of the preceding dose cohort. The full enrollment phase was to occur after completion of the sentinel phase. Local reactions were generally mild and adverse events infrequent; however, after only 46 infants were randomized into the study, fever rates were 64% and 90% in subjects receiving one 20- or 60-μg rLP2086 dose, respectively. Most fevers were group and 1 subject in the 60-μg group experienced fevers >39.0°C; no fevers were >40.0°C. Due to these high fever rates, the study was terminated early. No immunogenicity data were collected. This report discusses the safety and acceptability of rLP2086 in infants after one 20- or 60-μg dose. Due to the high fever rate experienced in the 20- and 60-μg groups, rLP2086 in the current formulation may not be acceptable for infants. Copyright © 2014. Published by Elsevier Ltd.

Lp-dual affine surface area forms of Busemann–Petty type problems

Indian Academy of Sciences (India)

Associated with the notion of Lp-intersection body which was defined ... Lp-dual affine surface area; Lp-intersection body; Busemann–Petty ..... [11] Schneider R, Convex Bodies: The Brunn–Minkowski Theory (1993) (Cambridge: Cam-.

Effects of inhibition of interleukin-6 signalling on insulin sensitivity and lipoprotein (a levels in human subjects with rheumatoid diseases.

Directory of Open Access Journals (Sweden)

Olaf Schultz

2010-12-01

Full Text Available Interleukin-6 (IL-6 is a pro-inflammatory cytokine that has been found to be increased in type 2 diabetic subjects. However, it still remains unclear if these elevated IL-6 levels are co-incidental or if this cytokine is causally related to the development of insulin resistance and type 2 diabetes in humans. Therefore, in the present study we examined insulin sensitivity, serum adipokine levels and lipid parameters in human subjects before and after treatment with the IL-6 receptor antibody Tocilizumab.11 non-diabetic patients with rheumatoid disease were included in the study. HOMA-IR was calculated and serum levels for leptin, adiponectin, triglycerides, LDL-cholesterol, HDL-cholesterol and lipoprotein (a (Lp (a were measured before as well as one and three months after Tocilizumab treatment. The HOMA index for insulin resistance decreased significantly. While leptin concentrations were not altered by inhibition of IL-6 signalling, adiponectin concentrations significantly increased. Thus the leptin to adiponectin ratio, a novel marker for insulin resistance, exhibited a significant decrease. Serum triglycerides, LDL-cholesterol and HDL-cholesterol tended to be increased whereas Lp (a levels significantly decreased.Inhibition of IL-6 signalling improves insulin sensitivity in humans with immunological disease suggesting that elevated IL-6 levels in type 2 diabetic subjects might be causally involved in the pathogenesis of insulin resistance. Furthermore, our data indicate that inhibition of IL-6 signalling decreases Lp (a serum levels, which might reduce the cardiovascular risk of human subjects.

LpMab-19 Recognizes Sialylated O-Glycan on Thr76 of Human Podoplanin.

Science.gov (United States)

Ogasawara, Satoshi; Kaneko, Mika K; Kato, Yukinari

2016-08-26

Human podoplanin (hPDPN) is expressed in lymphatic vessels, pulmonary type-I alveolar cells, and renal glomerulus. The hPDPN/C-type lectin-like receptor-2 (CLEC-2) interaction is involved in platelet aggregation and cancer metastasis. High expression of hPDPN in cancer cells or cancer-associated fibroblasts (CAFs) leads to a poor prognosis for cancer patients. In our previous research, we reported on several anti-hPDPN monoclonal antibodies (mAbs), including LpMab-2, LpMab-3, LpMab-7, LpMab-9, LpMab-12, LpMab-13, and LpMab-17 of mouse IgG 1 subclass, which were produced using CasMab technology. Here we produced a novel anti-hPDPN mAb LpMab-19 of mouse IgG 2b subclass. Flow cytometry revealed that the epitope of LpMab-19 includes O-glycan, which is attached to Thr76 of hPDPN. We further identified the minimum epitope of LpMab-19 as Thr76-Arg79 of hPDPN. Immunohistochemistry revealed that LpMab-19 is useful for detecting not only normal cells, including lymphatic vessels, but also glioblastoma and oral squamous cell carcinoma cells. LpMab-19 could be useful for investigating the physiological function of O-glycosylated hPDPN.

The relationship between oxidized lipoprotein(a and carotid atherosclerosis in asymptomatic subjects: A comparison with native lipoprotein(a

Directory of Open Access Journals (Sweden)

Taniguchi Nobuyuki

2011-10-01

Full Text Available Abstract Background Oxidized lipoprotein(a (oxLp(a can be a more potent marker of atherogenesis than native Lp(a, although Lp(a is considered to be a risk factor for atherosclerotic diseases. Limited clinical data are available regarding the significance of oxLp(a in atherosclerotic manifestations. This study aimed to investigate the association between the serum oxLp(a and carotid artery intima-media thickness (CIMT, in comparison to the serum Lp(a levels, among asymptomatic subjects. Methods The atheroscrerosis-related variables including Lp(a and oxLp(a were measured in 136 cardiovascular disease-free subjects (61 males and 75 females, mean age of 64 years. The serum oxLp(a level was quantified using a sandwich ELISA system. The CIMT level was ultrasonographically measured on bilateral carotid arteries. Results The median level of Lp(a was 120 μmol/L, oxLp(a was 0.06 nmol/L, and CIMT was 0.7 mm, respectively. A simple correlation test showed that the CIMT was significantly and positively correlated with age, systolic blood pressure and oxLp(a (r = 0.208, P Conclusions These results suggest that oxLp(a may be more closely associated with accelerated carotid atherosclerosis, in comparison to Lp(a, in this population. This finding can be important for obtaining a better understanding of the different atherogenic roles played by oxLp(a in comparison to Lp(a.

Genome-wide association study of Lp-PLA(2 activity and mass in the Framingham Heart Study.

Directory of Open Access Journals (Sweden)

Sunil Suchindran

2010-04-01

Full Text Available Lipoprotein-associated phospholipase A(2 (Lp-PLA(2 is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants have not been explored in a systematic, genome-wide fashion. We carried out a genome-wide association study of Lp-PLA(2 activity and mass in 6,668 Caucasian subjects from the population-based Framingham Heart Study. Clinical data and genotypes from the Affymetrix 550K SNP array were obtained from the open-access Framingham SHARe project. Each polymorphism that passed quality control was tested for associations with Lp-PLA(2 activity and mass using linear mixed models implemented in the R statistical package, accounting for familial correlations, and controlling for age, sex, smoking, lipid-lowering-medication use, and cohort. For Lp-PLA(2 activity, polymorphisms at four independent loci reached genome-wide significance, including the APOE/APOC1 region on chromosome 19 (p = 6 x 10(-24; CELSR2/PSRC1 on chromosome 1 (p = 3 x 10(-15; SCARB1 on chromosome 12 (p = 1x10(-8 and ZNF259/BUD13 in the APOA5/APOA1 gene region on chromosome 11 (p = 4 x 10(-8. All of these remained significant after accounting for associations with LDL cholesterol, HDL cholesterol, or triglycerides. For Lp-PLA(2 mass, 12 SNPs achieved genome-wide significance, all clustering in a region on chromosome 6p12.3 near the PLA2G7 gene. Our analyses demonstrate that genetic polymorphisms may contribute to inter-individual variation in Lp-PLA(2 activity and mass.

LEP dominates LP-HEP

Energy Technology Data Exchange (ETDEWEB)

Fraser, Gordon

1991-09-15

CERN's LEP electron-positron collider was the star of this year's major physics meeting - the Joint International Lepton-Photon Symposium and Europhysics Conference on High Energy Physics (LP-HEP) - held in Geneva from 25 July - 1 August.

78 FR 45592 - DeltaPoint Capital IV, LP;

Science.gov (United States)

2013-07-29

..., Suite 160, Pittsford, NY 14534. The financing was contemplated for working capital. The financing is... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0662] DeltaPoint Capital IV, LP; Notice Seeking... given that DeltaPoint Capital IV, L.P., 45 East Avenue, 6th Floor, Rochester, NY 14604, Federal...

Sparse Adaptive Channel Estimation Based on lp-Norm-Penalized Affine Projection Algorithm

Directory of Open Access Journals (Sweden)

Yingsong Li

2014-01-01

Full Text Available We propose an lp-norm-penalized affine projection algorithm (LP-APA for broadband multipath adaptive channel estimations. The proposed LP-APA is realized by incorporating an lp-norm into the cost function of the conventional affine projection algorithm (APA to exploit the sparsity property of the broadband wireless multipath channel, by which the convergence speed and steady-state performance of the APA are significantly improved. The implementation of the LP-APA is equivalent to adding a zero attractor to its iterations. The simulation results, which are obtained from a sparse channel estimation, demonstrate that the proposed LP-APA can efficiently improve channel estimation performance in terms of both the convergence speed and steady-state performance when the channel is exactly sparse.

LEP dominates LP-HEP

International Nuclear Information System (INIS)

Fraser, Gordon

1991-01-01

CERN's LEP electron-positron collider was the star of this year's major physics meeting - the Joint International Lepton-Photon Symposium and Europhysics Conference on High Energy Physics (LP-HEP) - held in Geneva from 25 July - 1 August

PuLP/XtraPuLP : Partitioning Tools for Extreme-Scale Graphs

Energy Technology Data Exchange (ETDEWEB)

2017-09-21

PuLP/XtraPulp is software for partitioning graphs from several real-world problems. Graphs occur in several places in real world from road networks, social networks and scientific simulations. For efficient parallel processing these graphs have to be partitioned (split) with respect to metrics such as computation and communication costs. Our software allows such partitioning for massive graphs.

CORN, LP Goldfield Approval

Science.gov (United States)

This November 19, 2015 letter from EPA approves the petition from CORN, LP, Goldfield facility, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS pro

Lp(a-cholesterol is associated with HDL-cholesterol in overweight and obese African American children and is not an independent risk factor for CVD

Directory of Open Access Journals (Sweden)

Sharma Sushma

2012-01-01

Full Text Available Abstract Background The role of Lipoprotein (a cholesterol {Lp(a-C}as an additional and/or independent risk factor for cardiovascular disease (CVD is not clear. We evaluated the associations between Lp(a-C and other CVD risk factors including plasma lipoprotein concentrations and body fatness in overweight and obese African American children. Methods A cross-sectional analysis was carried out using data from a sample of 121 African American children aged 9-11 years with Body Mass Index (BMI's greater than the 85th percentile. Body height, weight and waist circumference (WC were measured. Fasting plasma concentrations of Lp(a-C, Total cholesterol (TC, High density lipoprotein cholesterol (HDL-C, Very low density lipoprotein cholesterol (VLDL-C, Intermediate density lipoprotein cholesterol (IDL-C, Low density lipoprotein cholesterol (LDL-C, and Triacylglycerides (TAG were analyzed using the vertical auto profile (VAP cholesterol method. Results After adjusting for child age, gender, and pubertal status, Lp(a-C was positively associated with both HDL-C and TC, and negatively associated with VLDL-C and TAG. Including BMIz and WC as additional covariates did not alter the direction of the relationships between Lp(a-C and the other lipoproteins. Finally, after adjusting for the other plasma lipoproteins, Lp(a-C remained strongly associated with HDL-C, whereas the associations of Lp(a-C with the other lipoproteins were not significant when HDL-C was simultaneously included in the regression models. Conclusions Lp(a-C was positively associated with HDL-C and this association is not influenced by other lipoprotein subclasses or by the degree of obesity. We conclude that Lp(a cholesterol is not an independent risk factor for CVD in African American children.

Insulin Secretion and Risk for Future Diabetes in Subjects with a Nonpositive Insulinogenic Index

Directory of Open Access Journals (Sweden)

Daisuke Aono

2018-01-01

Full Text Available Aim. To characterize subjects with a nonpositive insulinogenic index and longitudinally observe changes in their glucose tolerance. Subjects and Methods. A historical cohort study was conducted using data from the medical checkups of public school workers. Indices of insulin secretion and insulin sensitivity derived from oral glucose tolerance test (OGTT and the incidences of diabetes and impaired glucose tolerance (IGT were compared among subgroups of subjects with different insulinogenic index (change in insulin/change in glucose over the first 30 min on the OGTT. Results. Of the 1464 nondiabetic subjects at baseline, 72 (4.9% subjects had a nonpositive insulinogenic index: 42 of those subjects had a nonpositive glucose response (ΔGlu0–30 ≤ 0 and 30 had a nonpositive insulin response (ΔIns0–30 ≤ 0. Compared with subjects who had normal glucose tolerance (NGT with insulinogenic index ≥ 0.4, subjects with a nonpositive glucose response had a higher first-phase Stumvoll and lower incidences of diabetes and IGT based on a log-rank test (p<0.05, whereas subjects with a nonpositive insulin response had lower indices of insulin secretion and a higher incidence of diabetes (p<0.05. Conclusions. These results demonstrate that in the first 30 min on the OGTT, subjects with a nonpositive insulinogenic index due to a nonpositive glucose response (ΔGlu0–30 ≤ 0 had a lower risk for future diabetes and that subjects with nonpositive insulin response (ΔIns0–30 ≤ 0 had a higher risk for future one.

75 FR 38514 - Application to Export Electric Energy; Brookfield Energy Marketing LP

Science.gov (United States)

2010-07-02

... Energy Marketing LP AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Brookfield Energy Marketing LP (BEM LP) has applied for authority to transmit electric... surplus energy purchased from electric utilities, Federal power marketing agencies and other entities...

The Smaller Alignment Index (SALI) applied in a study of stellar orbits in barred galaxies potential models using the LP-VIcode

Science.gov (United States)

Caritá, Lucas Antonio; Rodrigues, Irapuan; Puerari, Ivânio; Schiavo, Luiz Eduardo Camargo Aranha

2018-04-01

The Smaller Alignment Index (SALI) is a mathematical tool, not yet conventional, for chaos detection in the phase space of Hamiltonian Dynamical Systems. The SALI values has temporal behaviors very specific to ordered or chaotic motions, what makes the distinction between order and chaos easily observable in these systems. In this paper, this method will be applied to the stability study of stellar orbits immersed in gravitational potential of barred galaxies, since the motion of a test particle in a rotating barred galaxy model is given by a Hamiltonian function. Extracting four parameter sets from the Manos and Athanassoula (2011) work and elaborating a different initial conditions set for each case, we were able to introduce another point of view of their stability study for two degrees of freedom. We have also introduced two new extreme models that corroborates with the conclusions that more axisymmetric bars create an environment with less chaos and that more massive bars create an environment with more chaos. Separate studies were carried out for prograde and retrograde orbits that showed that the retrograde orbits seem more conducive to chaos. To perform all the orbits integrations we used the LP-VIcode program.

Online lektiehjælp

DEFF Research Database (Denmark)

Hansen, Jens Jørgen; Remvig, Kirstin

2016-01-01

vejledningsdidaktik, herunder metoder, modeller og materialer for lektievejledning i regi af Lektier Online. Lektier Online er en organisation ved Statsbiblioteket i Århus, der tilbyder en online lektiecafe, hvor bl.a. gymnasie-elever kan få hjælp af frivillige universitetsstuderende. Dette didaktiske de-sign er et...

Bragg grating induced cladding mode coupling due to asymmetrical index modulation in depressed cladding fibers

DEFF Research Database (Denmark)

Berendt, Martin Ole; Grüne-Nielsen, Lars; Soccolich, C.F.

1998-01-01

to reduce this problem. None of these designs seems to give complete solutions. In particular, the otherwise promising depressed cladding design gives a pronounced coupling to one LP01 mode, this has been referred to as a Ghost grating. To find the modes of the fiber we have established a numerical mode......UV-written Bragg gratings find wide spread use as wavelength selective components. In reflection high extinction ratios are routinely obtained. However, coupling to cladding modes gives excess loss on the short wavelength side of the main reflection. Different fiber-designs have been proposed......-solver based on the staircase-approximation method. The Bragg grating causes coupling between the fundamental LP01 mode and higher order LP1p modes that satisfy phase-matching. The coupling strength is determined by the overlap integral of the LP01, the LP1p mode, and the UV-induced index perturbation. For LP0...

2-LP mode few-mode fiber amplifier employing ring-core erbium-doped fiber.

Science.gov (United States)

Ono, Hirotaka; Hosokawa, Tsukasa; Ichii, Kentaro; Matsuo, Shoichiro; Nasu, Hitoshi; Yamada, Makoto

2015-10-19

A fiber amplifier supporting 2 LP modes that employs a ring-core erbium-doped fiber (RC-EDF) is investigated to reduce differential modal gain (DMG). The inner and outer radii of the ring-core of the RC-EDF are clarified for 2-LP mode operation of the amplifier, and are optimized to reduce the DMG. It is shown that using the overlap integral between the erbium-doped core area and the signal power mode distribution is a good way to optimize the inner and outer radii of the ring-core of the RC-EDF and thus minimize the DMG. A fabricated RC-EDF and a constructed 2-LP mode EDFA are described and a small DMG of around 1 dB is realized for LP01, LP11 and LP21 pumping.

LpMab-23: A Cancer-Specific Monoclonal Antibody Against Human Podoplanin.

Science.gov (United States)

Yamada, Shinji; Ogasawara, Satoshi; Kaneko, Mika K; Kato, Yukinari

2017-04-01

Human podoplanin (hPDPN), the ligand of C-type lectin-like receptor-2, is involved in cancer metastasis. Until now, many monoclonal antibodies (mAbs) have been established against hPDPN. However, it is still difficult to develop a cancer-specific mAb (CasMab) against hPDPN because the protein sequence of hPDPN expressed in cancer cells is the same as that in normal cells. Herein, we report LpMab-23 of the mouse IgG 1 subclass, a novel CasMab against hPDPN. In an immunohistochemical analysis, LpMab-23 reacted with tumor cells of human oral cancer, but did not react with normal cells such as lymphatic endothelial cells (LECs). In contrast, LpMab-17, another anti-hPDPN mAb, reacted with both tumor cells and LECs. Furthermore, flow cytometric analysis revealed that LpMab-23 reacted with hPDPN-expressing cancer cell lines (LN319, RERF-LC-AI/hPDPN, Y-MESO-14/hPDPN, and HSC3/hPDPN) but showed little reaction with normal cells (LECs and HEK-293T), although another anti-hPDPN mAb, LpMab-7, reacted with both hPDPN-expressing cancer cells and normal cells, indicating that LpMab-23 is a CasMab against hPDPN.

LP-THAE induced tumor cell apoptosis of rabbit VX2 liver carcinoma

International Nuclear Information System (INIS)

Chen Shengli; Quan Yi; Huang Zicheng; Chen Guodong; Zhu Dongliang

2007-01-01

Objective: To research tumor cell apoptosis induced by Lp-THAE of rabbit VX2 liver implanted tumor. Methods: 27 New Zealand white rabbits implanted with VX2 tumor at left middle lobe of the liver divided into three groups: Group A(n= 9) Lp-THAE: treated through transhepatic artery catheterization; Group B(n=9) THAI and Group C(n=9) as control. The rabbits were executed at second to fifth day after treatment. HE dye microscopy was taken for counting the typical apoptosis cells and calculating apoptosis index (ApI). FITC-AnnexinV/PI assay was used for measuring apoptosis by flow cytometry. Results: The ApI of tumor central area and marginal area were (17.769±2.417)%, (4.129±1.172)%, P<0.01. The percentages of tumor cell apoptosis and tumor cell necrosis were (16.483±1.404)%, (9.478±0.964)%, P<0.01 and (43.559±5.053)%, (33.460±1.840)%, P=0.093. The total percentages of tumor cell apoptosis and necrosis were (60.042±13.979)%, (42.938±8.979)%, P< 0.01, at tumor center and marginal area in THAE group respectively. The ApI, percentages of tumor cell apoptosis and necrosis in THAE group were significantly higher than those of THAI group (P<0.01). The percentages of tumor cell apoptosis at tumor center area in THAE group were significantly higher than those of tumor marginal area(P<0.01). Conclusion: Induced tumor cell apoptosis and necrosis are two mechanisms of action for Lp-THAE treatment of liver carcinoma. (authors)

On indexes and subject matter of “global competitiveness”

Directory of Open Access Journals (Sweden)

A. V. Korotkov

2017-01-01

Full Text Available The aim of the research is to analyze the subject matter of a country’s competitiveness and to characterize statistical indexes of competitiveness known in the international practice from the perspective of a more elaborated theory of market competition. This aim follows from the identified problems. First, there are no generally accepted interpretation and joint understanding of competition and competitiveness at country level. Even the international organizations giving estimations of global competitiveness disagree on definitions of competitiveness. Secondly, there is no relation to the theory of market competition in the available source materials on competitiveness of the country without original methodology. Thirdly, well-known statistical indexes of global competitiveness do not have enough theoretical justification and differ in sets of factors. All this highlights the incompleteness of the methodology and methodological support of studying competitiveness at country level.Materials and methods. The research is based on the methodology of statistics, economic theory and marketing. The authors followed the basic principle of statistical methodology – requirement of continuous combination of qualitative and quantitative analysis, when the research begins and ends with qualitative analysis. A most important section of statistical methodology is widely used – construction of statistical indexes. In the course of the analysis, a method of statistical classifications is applied. A significant role in the present research is given to the method of generalizing and analogue method, realizing that related terms should mean similar and almost similar contents. Modeling of competition and competitiveness is widely used in the present research, which made it possible to develop a logical model of competition following from the competition theory.Results. Based on the definitions’ survey the analysis of the subject matter of global

LibraryH3lp: A New Flexible Chat Reference System

Directory of Open Access Journals (Sweden)

Pam Sessoms

2008-09-01

Full Text Available LibraryH3lp is an integrated IM and web chat system designed specifically for Virtual Reference services in libraries. The software was designed for, and is currently used by, a night-time chat reference collaboraton between several large academic libraries. LibraryH3lp is designed for the workflow of chat reference, supporting multiple simultaneous operators and routing to queues of operators in a particular service area. It also supports web page embeddable chat 'widgets', as well as simultaneous gateways to multiple IM protocols. This article discusses the motivation for the development of the software, and provides an overview of LibraryH3lp's features and technical architecture. Parts of LibraryH3lp are available as open source. The complete application is available as a low-cost hosted service, and will eventually be available to be licensed for local hosting.

Lipoprotein-Associated Phospholipase A2 Mass Level Is Increased in Elderly Subjects with Type 2 Diabetes Mellitus

Directory of Open Access Journals (Sweden)

J. Fortunato

2014-01-01

Full Text Available Objective. Lipoprotein-associated phospholipase A2 (Lp-PLA2 is extensively expressed by advanced atherosclerotic lesions and may play a role in plaque instability. We selected a group of elderly subjects that underwent transcatheter aortic valve implantation (TAVI or balloon angioplasty (BA and separated them into two groups, diabetic and nondiabetic, to compare the level of Lp-PLA2 mass between them. Methods. 44 patients aged 79.6±5.6 years with symptomatic severe aortic valve stenosis underwent TAVI (n=35 or BA (n=9. 21 subjects had confirmed type 2 diabetes mellitus. Lp-PLA2 mass was measured using an enzyme-linked immunosorbent assay kit (USCN Life Science, China before and 3 days after the procedure. Results. Lp-PLA2 mass was significantly elevated in this population (1296±358 ng/mL before TAVI; 1413±268 ng/mL before BA and further increased after TAVI (1604±437 ng/mL, P<0.01 or BA (1808±303 ng/mL, P<0.01. Lp-PLA2 mass was significantly increased on the diabetic group before these interventions. Conclusion. Lp-PLA2 may be a novel biomarker for the presence of rupture-prone atherosclerotic lesions in elderly patients. Levels of Lp-PLA2 in diabetic patients may accompany the higher amount of small dense LDL particles seen in these subjects.

76 FR 49760 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2011-08-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-524-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on July 29, 2011, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056-5310, filed with the Federal Energy...

76 FR 7833 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2011-02-11

...] Texas Eastern Transmission, LP; Notice of Application Take notice that on January 25, 2011, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in the above... TEAM 2012 Project. Specifically, Texas Eastern requests: (i) Authorization under NGA sections 7(b) and...

New low pressure (LP) turbines for NE Krsko

International Nuclear Information System (INIS)

Nemcic, K.; Novsak, M.

2004-01-01

During the evaluation of possible future maintenance strategies on steam turbine in very short period of time, engineering decision was made by NE Krsko in agreement with Owners to replace the existing two Low Pressure (LP) Turbines with new upgrading LP Turbines. This decision is presented with review of the various steam turbine problems as: SCC on turbine discs; blades cracking; erosion-corrosion with comparison of various maintenance options and efforts undertaken by the NE Krsko to improve performance of the original low pressure turbines. This paper presents the NEK approach to solve the possible future problems with steam turbine operation in NE Krsko as pro-active engineering and maintenance activities on the steam turbine. This paper also presents improvements involving retrofits, confined to the main steam turbine path, with major differences between original and new LP Turbines as beneficial replacement because of turbine MWe upgrading and return capital expenditures.(author)

The role of LP gas in eradicating energy poverty

Energy Technology Data Exchange (ETDEWEB)

Kelly, Michael; Behuria, Sarthak

2010-09-15

LP Gas is an ideal solution for dealing with energy poverty. Clean burning, low carbon, extremely efficient, requiring minimal infrastructure or R and D investment and with plentiful long term global supply, LP Gas can be quickly introduced to play an important role in eradicating energy poverty and steering both industrialised and developing countries onto more sustainable energy development paths.

78 FR 43874 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2013-07-22

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP13-514-000] Texas Eastern Transmission, LP; Notice of Application On July 2, 2013, Texas Eastern Transmission, LP (Texas Eastern) filed... natural gas facilities no longer in service. As described more fully in the Application, Texas Eastern...

76 FR 38381 - Texas Eastern Transmission, LP; Notice of Amendment

Science.gov (United States)

2011-06-30

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-67-001] Texas Eastern Transmission, LP; Notice of Amendment Take notice that on June 13, 2011, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in the above referenced docket an amendment...

77 FR 20015 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2012-04-03

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-88-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on March 19, 2012, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056-5310, filed an application in Docket No...

77 FR 12045 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2012-02-28

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-68-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on February 16, 2012, Texas Eastern Transmission, LP (Texas Eastern), PO Box 1642, Houston, Texas 77056 filed an application in the above referenced docket...

78 FR 32294 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P., License No. 02/02-0662,02/02...

Science.gov (United States)

2013-05-29

... Small Business Investment Act of 1958, as amended (``the Act''), in connection with the financing of a... SMALL BUSINESS ADMINISTRATION DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P., License No. 02/02-0662,02/02-0661; Notice Seeking Exemption Under Section 312 of the Small Business...

78 FR 66352 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2013-11-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP14-9-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on October 17, 2013, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed an application in Docket No. CP14-9...

78 FR 79687 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2013-12-31

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP14-29-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on December 10, 2013 Texas Eastern Transmission, LP (Texas Eastern), at 5400 Westheimer Court, Houston, Texas 77056, filed an application in Docket No. CP14...

77 FR 26534 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2012-05-04

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-164-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on April 19, 2012, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in Docket No. CP12-164-000, a request...

Influence of fruit drinks with or without lactobacillus Lp299v on the gastrointestinal uptake of paracetamol in man

DEFF Research Database (Denmark)

Akerman, Ulrika; Edvinsson, Lars

2009-01-01

subjects consuming 200 ml of water, Rose hip drink or Proviva together with 1.5 gram of paracetamol. FINDINGS: The concentration of paracetamol in plasma increased rapidly when the paracetamol-containing tablets were consumed together with water and after 30 minutes a median level of 90 mumol/l was reached...... concentration and in time to maximal paracetamol concentration. The median maximal paracetamol concentration was 147 mumol/l for water, which is significantly higher than the median for rosehip drink with Lp299v,113.5 mumol/l, and than the median for rosehip-drink without Lp299v, 106.5 mumol/l (p = 0.002, and p...

Significance of Lipiodol-CT in the evaluation of therapeutic effects of Lp-TAE for hepatocellular carcinoma

International Nuclear Information System (INIS)

Jinno, Kenji; Tokuyama, Katuyuki; Yumoto, Yasuhiro

1988-01-01

In 20 lesions of 17 patients treated with arterial infusion of SMANCS dissolved in lipiodol (Lp) and transcatheter arterial embolization (TAE) for hepatocellular carcinoma (HCC), Lp deposition within the tumor were depicted on CT (Lp-CT). The findings of Lp-CT were compared with those of macroscopic, soft X-ray, and histologic examinations for resected specimens. Lp-CT appearance of HCC fell into four types: (I) complete type - round and homogeneous high density area (HDA) - in which Lp was deposited over the whole area; (II) defective type - inhomogeneous HDA - in which Lp was deposited in part of the tumor; (III) aggregated type - aggregation of small HDA; (IV) deficient type - no HDA - in which little or no Lp was deposited. Type I was found in 20 % of the lesions, type II in 25 %, type III in 20 %, and type IV in 35 %. In type I, HCC was of macroscopically nodular form with expansive growth and pseudocapsule and of histologically trabecular form with broad blood spaces and inviable cancer cells. In the other types, similar findings were seen in the necrotic area in which Lp was deposited, whereas scirrhous or compact type of HCC was histologically seen in the area containing viable cancer cells in which no Lp was deposited. The presence or not of Lp deposition, as depicted on CT, was closely correlated with histologic findings, which has significant implications for the evaluation of therapeutic efficacy of TAE with Lp. (Namekawa, K.)

Bivalent rLP2086 Vaccine (Trumenba(®)): A Review in Active Immunization Against Invasive Meningococcal Group B Disease in Individuals Aged 10-25 Years.

Science.gov (United States)

Shirley, Matt; Dhillon, Sohita

2015-10-01

Bivalent rLP2086 vaccine (Trumenba(®)) [hereafter referred to as rLP2086] is a Neisseria meningitidis serogroup B (MenB) vaccine recently licensed in the USA for active immunization to prevent invasive disease caused by MenB in individuals 10-25 years of age. rLP2086, which contains two variants of the meningococcal surface protein factor H-binding protein (fHBP), was approved by the FDA under the accelerated approval pathway after the immunogenicity of the vaccine was demonstrated in several phase II trials. This article reviews the immunogenicity and reactogenicity of rLP2086 as demonstrated in the trials with a focus on the US setting and on use of the vaccine as per FDA-approved labeling. rLP2086 is approved in the USA as a three-dose series administered in a 0-, 2-, and 6-month schedule. In the phase II trials, rLP2086 elicited a robust immune response against a panel of MenB test strains. A strong immune response was evident in a marked proportion of subjects after two vaccine doses, with a further increase after a third dose. The four primary test strains used were selected to be representative of MenB strains prevalent in the USA, with each expressing an fHBP variant heterologous to the vaccine antigens. rLP2086 was generally well tolerated in the trials, with most adverse reactions being mild to moderate in severity. Although some questions remain, including the duration of the protective response, rLP2086 vaccine has the potential to be a valuable tool for the prevention of invasive MenB disease.

78 FR 11567 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2013-02-19

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39...

76 FR 70040 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2011-11-10

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Aerospace LP (type certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and... new AD: 2011-23-07 Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft...

Numerical investigation of a dual-loop EGR split strategy using a split index and multi-objective Pareto optimization

International Nuclear Information System (INIS)

Park, Jungsoo; Song, Soonho; Lee, Kyo Seung

2015-01-01

Highlights: • Model-based control of dual-loop EGR system is performed. • EGR split index is developed to provide non-dimensional index for optimization. • EGR rates are calibrated using EGR split index at specific operating conditions. • Multi-objective Pareto optimization is performed to minimize NO X and BSFC. • Optimum split strategies are suggested with LP-rich dual-loop EGR at high load. - Abstract: A proposed dual-loop exhaust-gas recirculation (EGR) system that combines the features of high-pressure (HP) and low-pressure (LP) systems is considered a key technology for improving the combustion behavior of diesel engines. The fraction of HP and LP flows, known as the EGR split, for a given dual-loop EGR rate play an important role in determining the engine performance and emission characteristics. Therefore, identifying the proper EGR split is important for the engine optimization and calibration processes, which affect the EGR response and deNO X efficiencies. The objective of this research was to develop a dual-loop EGR split strategy using numerical analysis and one-dimensional (1D) cycle simulation. A control system was modeled by coupling the 1D cycle simulation and the control logic. An EGR split index was developed to investigate the HP/LP split effects on the engine performance and emissions. Using the model-based control system, a multi-objective Pareto (MOP) analysis was used to minimize the NO X formation and fuel consumption through optimized engine operating parameters. The MOP analysis was performed using a response surface model extracted from Latin hypercube sampling as a fractional factorial design of experiment. By using an LP rich dual-loop EGR, a high EGR rate was attained at low, medium, and high engine speeds, increasing the applicable load ranges compared to base conditions

SUBJECT AND AUTHOR INDEXS

Directory of Open Access Journals (Sweden)

IJBE Volume 1

2015-09-01

Full Text Available SUBJECT INDEX IJBE VOLUME 1EPA, 1Agrotourism, 148AHP, 148balance scorecard, 63batik tulis Rolla Junior, 23Broiler, 90business model canvas, 137business performance,32capital structure, 81cashew industry,158CHAID,106CLI,42coal transportation service,63company’s characteristics, 81competitive advantage, 12competitive strategy, 127consumer satisfaction, 51CSI, 42customer loyalty, 42customer satisfaction,42decision of visitors, 72development strategy, 23development,158entrepreneurship, 32Feasibility studies, 90FEM, 81gap analysis, 1Indonesia Stock Exchange, 177Indosat, 137investor,177Kawah Putih, 72kedai sop durian lodaya (KSDL,51klassen typology, 96leading sector, 96less cash society, 137liquidity ratio, 165location quotient, 96logistic regression, 115market, 177marketing development strategy, 148Marketing mix, 72mobile payment, 137modern and Traditional cage, 90multiple regression analyse,165multiple regression, 177net working capital, 165organic tofu product, 115Padang, 106paired comparison, 63partnership, 1, 32Pecking Order Theory, 81PLS, 81Portfolio, 96power, 32product quality, 51profitability ratio, 165Prol Tape Primadona, 127purchase decision, 115purchase intention, 51purchasing interest,115QSPM, 23, 127refilled drinking water, 106seed,1segmentation, 106SEM, 42, 51service quality, 51SMEs, 96specialty coffee, 12stock,177strategic diagnosis,137strategy, 158Sukorambi Botanic Garden, 148SWOT, 23, 127, 148, 158SWOT-AHP, 12tourists,72UD. Primadona, 127value chain, 12VRIO,12 AUTHOR INDEX IJBE VOLUME 1Adiningsih, Kartika Puspitasari,42Aknesia, Vharessa,12Amalia, Firda Rachma,90Andati, Trias, 177Anggraeni, Lukytawati,23Asriani,158Daryanto, Arief,12, 90Djamaludin, MD., 42Djohar, Setiadi,96Fachrodji, Achmad,72Fahmi, Idqan,1, 63, 127Fasyni, Awisal,106Hubeis, Musa,148Iskandar, Dodi,51Juanda, Bambang, 165Kirbrandoko, 12, 106, 115Lumbantoruan, Dewi Margareth,96Maulana, TB Nur Ahmad,81Muksin, 148Mukti Soleh, Cecep,63Najib, Mukhamad,106Noor, Tajudin,81

On $L_p$ Affine Surface Area and Curvature Measures

OpenAIRE

Zhao, Yiming

2015-01-01

The relationship between $L_p$ affine surface area and curvature measures is investigated. As a result, a new representation of the existing notion of $L_p$ affine surface area depending only on curvature measures is derived. Direct proofs of the equivalence between this new representation and those previously known are provided. The proofs show that the new representation is, in a sense, "polar" to that of Lutwak's and "dual" to that of Sch\\"utt & Werner's.

A New Algorithm for Detecting Cloud Height using OMPS/LP Measurements

Science.gov (United States)

Chen, Zhong; DeLand, Matthew; Bhartia, Pawan K.

2016-01-01

The Ozone Mapping and Profiler Suite Limb Profiler (OMPS/LP) ozone product requires the determination of cloud height for each event to establish the lower boundary of the profile for the retrieval algorithm. We have created a revised cloud detection algorithm for LP measurements that uses the spectral dependence of the vertical gradient in radiance between two wavelengths in the visible and near-IR spectral regions. This approach provides better discrimination between clouds and aerosols than results obtained using a single wavelength. Observed LP cloud height values show good agreement with coincident Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) measurements.

Amplitude and Recurrence Time of LP activity at Mt. Etna, Italy

Science.gov (United States)

Cauchie, Léna; Saccorotti, Gilberto; Bean, Christopher

2013-04-01

The manifestation of Long-Period (LP) activity is attested on many volcanoes worldwide and is thought to be associated with the resonant oscillations of subsurface, fluid-filled, cracks and conduits. Nonetheless the actual source mechanism that originates the resonance is still unclear. Different models have been proposed so far, including (i) fluid flow instabilities as periodic degassing and (ii) brittle failure in viscous magmas. Since LP activity usually precedes and accompanies volcanic eruption, the understanding of these sources is crucial for the hazard assessment and eruption early warning. The work is aimed at improving the understanding of the LP source mechanism through a statistical analysis of detailed LP catalogues. The behaviour of LP activity is compared with the empirical laws governing earthquakes recurrence (e.g., Gutenberg-Richter [GR] and Gamma-law distributions), in order to understand what relationships, if any, exist between these two apparently different earthquake classes. In particular, about 13000 events were detected on Mount Etna in August 2005 through a STA/LTA method. For this given period, the volcano does not present particular sign of unrest. The manifestation of the LP events is sustained in time over all the period of analysis. From the analysis of the directional properties, it turns out that the events of this first catalog propagate from 2 distinct sources . Furthermore, the events exhibit a high degree of waveform similarity, and provide a criterion for classification/source separation. The events were then grouped into families of comparable waveforms, resulting also in a separation for their source locations. We then used template signals of each family for a Matched-Filtering of the continuous data streams, in order to discriminate small-amplitude events previously undetected by the STA/LTA triggering method. This procedure allowed for a significant enrichment of the catalogues. The retrieved amplitude distributions

78 FR 69078 - Houston Pipe Line Company LP; Notice of Application

Science.gov (United States)

2013-11-18

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP14-13-000] Houston Pipe Line Company LP; Notice of Application Take notice that on October 28, 2013, Houston Pipe Line Company LP (HPL), 1300 Main Street, Houston, Texas 77002, filed an application in Docket No. CP14-13-000...

Influence of fruit drinks with or without lactobacillus Lp299v on the gastrointestinal uptake of paracetamol in man

Directory of Open Access Journals (Sweden)

Edvinsson Lars

2009-03-01

Full Text Available Abstract Background Clinical observations have revealed that patients throw up undigested paracetamol tablets several hours following intake of rosehip drink with Lp299v (Proviva. The purpose of this study was to demonstrate if this translates into altered plasma levels of paracetamol in nineteen healthy subjects consuming 200 ml of water, Rose hip drink or Proviva together with 1.5 gram of paracetamol. Findings The concentration of paracetamol in plasma increased rapidly when the paracetamol-containing tablets were consumed together with water and after 30 minutes a median level of 90 μmol/l was reached (a 95% confidence interval of 57,161. The corresponding 30 minutes values of paracetamol levels in the presence of rosehip with or without Lp299v were 0 μmol/l (95% confidence intervals contain only zero for both rosehip treatments. There were significant differences in AUC, maximal paracetamol concentration and in time to maximal paracetamol concentration. The median maximal paracetamol concentration was 147 μmol/l for water, which is significantly higher than the median for rosehip drink with Lp299v,113.5 μmol/l, and than the median for rosehip-drink without Lp299v, 106.5 μmol/l (p = 0.002, and p = 0.003; there were no significant difference between rosehip drink with or without Lp299v (p > 0.3. Conclusion We have demonstrated an interaction between the uptake of paracetamol and the solvent in rosehip drink/Provia which mainly consists of long chain carbohydrates. This may in the clinic translate to the use of more drug than it is necessary.

Arterial stiffness evaluation by cardio-ankle vascular index in hypertension and diabetes mellitus subjects.

Science.gov (United States)

Wang, Hongyu; Liu, Jinbo; Zhao, Hongwei; Fu, Xiaobao; Shang, Guangyun; Zhou, Yingyan; Yu, Xiaolan; Zhao, Xujing; Wang, Guang; Shi, Hongyan

2013-01-01

Arterial stiffness is an independent predictor for vascular diseases. Cardio-ankle vascular index (CAVI) is a new index of arterial stiffness. In the present study, we investigated the possible risk factors involving CAVI in hypertension and diabetes mellitus (DM) subjects. One thousand sixty-three subjects (M/F 533/530) from Shougang Corporation Examination Center were divided into four groups: healthy group (n = 639); hypertension group (n = 312); DM group (n = 58); and hypertension with DM group (n = 54). CAVI was measured by VS-1000 apparatus. Our results showed that CAVI was significantly higher in hypertension subjects with DM than in healthy and hypertension group, respectively (8.59 ± 1.08 vs 7.23 ± 1.10; 8.59 ± 1.08 vs 7.94 ± 1.33; both P hypertension subjects with DM compared with healthy and hypertension groups. Copyright © 2013 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.

Analysis of error floor of LDPC codes under LP decoding over the BSC

Energy Technology Data Exchange (ETDEWEB)

Chertkov, Michael [Los Alamos National Laboratory; Chilappagari, Shashi [UNIV OF AZ; Vasic, Bane [UNIV OF AZ; Stepanov, Mikhail [UNIV OF AZ

2009-01-01

We consider linear programming (LP) decoding of a fixed low-density parity-check (LDPC) code over the binary symmetric channel (BSC). The LP decoder fails when it outputs a pseudo-codeword which is not a codeword. We propose an efficient algorithm termed the instanton search algorithm (ISA) which, given a random input, generates a set of flips called the BSC-instanton and prove that: (a) the LP decoder fails for any set of flips with support vector including an instanton; (b) for any input, the algorithm outputs an instanton in the number of steps upper-bounded by twice the number of flips in the input. We obtain the number of unique instantons of different sizes by running the ISA sufficient number of times. We then use the instanton statistics to predict the performance of the LP decoding over the BSC in the error floor region. We also propose an efficient semi-analytical method to predict the performance of LP decoding over a large range of transition probabilities of the BSC.

Plasma Lp-PLA2 mass and apoB-lipoproteins that carry Lp-PLA2 decrease after sodium

NARCIS (Netherlands)

Constantinides, Alexander; Kerstens, Michiel N.; Dikkeschei, Bert D.; van Pelt, L. Joost; Tellis, Constantinos C.; Tselepis, Alexandros D.; Dullaart, Robin P. F.

2012-01-01

Eur J Clin Invest 2012; 42 (11): 12351243 Abstract Background Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a novel cardiovascular risk marker, which is predominantly complexed to apolipoprotein (apo) B-containing lipoproteins in human plasma. As increasing dietary sodium intake may decrease

Convex Hypersurfaces and $L^p$ Estimates for Schr\\"odinger Equations

OpenAIRE

Zheng, Quan; Yao, Xiaohua; Fan, Da

2004-01-01

This paper is concerned with Schr\\"odinger equations whose principal operators are homogeneous elliptic. When the corresponding level hypersurface is convex, we show the $L^p$-$L^q$ estimate of solution operator in free case. This estimate, combining with the results of fractionally integrated groups, allows us to further obtain the $L^p$ estimate of solutions for the initial data belonging to a dense subset of $L^p$ in the case of integrable potentials.

Comparison between metalloproteinases-2 and -9 in healthy subjects, diabetics, and subjects with acute coronary syndrome.

Science.gov (United States)

Derosa, Giuseppe; D'Angelo, Angela; Scalise, Filippo; Avanzini, Maria A; Tinelli, Carmine; Peros, Emmanouil; Fogari, Elena; Cicero, Arrigo F G

2007-11-01

We hypothesized that matrix metalloproteinase (MMP)-2, -9, and tissue inhibitor metalloproteinase-1, -2 (TIMP-1, -2) would be abnormal in diabetes and in acute coronary syndromes (ACS). We measured MMP-2, -9, and TIMP-1, -2 plasma levels in healthy subjects (controls), in type 2 diabetic patients, in nondiabetic patients with ACS (ACS) and in diabetic patients with ACS (DACS). We enrolled 165 controls, 181 diabetic patients, 78 ACS, and 46 DACS. We measured also BMI (body mass index), HbA(1c) (glycated hemoglobin) FPG (fasting plasma glucosa), FPI (fasting plasma insulin), HOMA index (homeostasis model assessment index), SBP (systolic blood pressure), DBP (diastolic blood pressure), TC (total cholesterol), LDL-C (low density lipoprotein cholesterol), HDL-C (high-density lipoprotein cholesterol), Tg (triglycerides), Lp(a) (lipoprotein(a)) PAI-1 (plasminogen activator inhibitor-1), Hct (homocysteine), Fg (fibrinogen), and hs-CRP (high-sensitivity C-reactive protein). A significant increase of BMI was observed in the diabetic group, in ACS and DACS patients compared to controls. A significant increase of SBP and DBP resulted in the diabetic and DACS groups, while only SBP improvement was present in ACS patients with respect to controls. A decrease in SBP and DBP was observed in the ACS group, while SBP variation was present in DACS patients compared to diabetics, and DBP increase was obtained in the DACS group with respect to ACS patients. TC, LDL-C, Tg, and Lp(a) increase was present in diabetics, while TC, Tg, and Lp(a) improvement was present in ACS and DACS patients with a significant decrease of HDL-C levels in diabetic, ACS, and DACS groups compared to controls. A decrease in LDL-C was obtained in ACS and DACS groups, while HDL-C increase was observed in these patients with respect to diabetics. Tg levels were higher in the DACS group compared to diabetics and ACS patients, respectively. Increases in PAI-1, Hct, Fg, and hs-CRP were present in diabetic and DACS

Fatty Liver Index and Lipid Accumulation Product Can Predict Metabolic Syndrome in Subjects without Fatty Liver Disease

Directory of Open Access Journals (Sweden)

Yuan-Lung Cheng

2017-01-01

Full Text Available Background. Fatty liver index (FLI and lipid accumulation product (LAP are indexes originally designed to assess the risk of fatty liver and cardiovascular disease, respectively. Both indexes have been proven to be reliable markers of subsequent metabolic syndrome; however, their ability to predict metabolic syndrome in subjects without fatty liver disease has not been clarified. Methods. We enrolled consecutive subjects who received health check-up services at Taipei Veterans General Hospital from 2002 to 2009. Fatty liver disease was diagnosed by abdominal ultrasonography. The ability of the FLI and LAP to predict metabolic syndrome was assessed by analyzing the area under the receiver operating characteristic (AUROC curve. Results. Male sex was strongly associated with metabolic syndrome, and the LAP and FLI were better than other variables to predict metabolic syndrome among the 29,797 subjects. Both indexes were also better than other variables to detect metabolic syndrome in subjects without fatty liver disease (AUROC: 0.871 and 0.879, resp., and the predictive power was greater among women. Conclusion. Metabolic syndrome increases the cardiovascular disease risk. The FLI and LAP could be used to recognize the syndrome in both subjects with and without fatty liver disease who require lifestyle modifications and counseling.

SUBJECT AND AUTHOR INDEXS

Directory of Open Access Journals (Sweden)

IJBE Volume 2

2016-09-01

Full Text Available SUBJECT INDEX IJBE VOLUME 2access credit, 93acquisition, 177AHP, 61, 82, 165arena simulation,43BMC, 69Bojonegoro, 69brand choice, 208brand image, 208brand positioning, 208bullwhip effect, 43burger buns, 1business synergy and financial reports, 177capital structure, 130cluster, 151coal reserves, 130coffee plantation, 93competitiveness, 82consumer behaviour, 33consumer complaint behavior, 101cooking spices, 1crackers, 1cross sectional analytical, 139crosstab, 101CSI, 12direct selling, 122discriminant analysis, 33economic value added, 130, 187employee motivation, 112employee performance, 112employees, 139EOQ, 23farmer decisions, 93farmer group, 52financial performance evaluation, 187financial performance, 52, 177financial ratio, 187financial report, 187fiva food, 23food crops, 151horticulture, 151imports, 151improved capital structure, 177IPA, 12leading sector, 151life insurance, 165LotteMart, 43main product, 61marketing mix, 33, 165matrix SWOT, 69MPE, 61multiple linear regression, 122muslim clothing, 197Ogun, 139Pangasius fillet, 82Pati, 93pearson correlation, 101perceived value, 208performance suppy chain, 23PLS, 208POQ, 23portfolio analyzing, 1product, 101PT SKP, 122pulp and papers, 187purchase decision, 165purchase intention, 33remuneration, 112re-purchasing decisions, 197sales performance, 122sawmill, 52SCOR, 23sekolah peternakan rakyat, 69SEM, 112SERVQUAL, 12Sido Makmur farmer groups, 93SI-PUHH Online, 12small and medium industries (IKM, 61socio-demographic, 139sport drink, 208stress, 139supply chain, 43SWOT, 82the mix marketing, 197Tobin’s Q, 130trade partnership, 52uleg chili sauce, 1 AUTHOR INDEX IJBE VOLUME 2Achsani, Noer Azam, 177Andati, Trias, 52, 177Andihka, Galih, 208Arkeman, Yandra, 43Baga, Lukman M, 69Cahyanugroho, Aldi, 112Daryanto, Arief, 12David, Ajibade, 139Djoni, 122Fahmi, Idqan, 1Fattah, Muhammad Unggul Abdul, 61Hakim, Dedi Budiman, 187Harianto, 93Hartoyo, 101Homisah, 1Hubeis, Musa, 112Hutagaol, M. Parulian, 93Jaya, Stevana

Bibliography, subject index, and author index of the literature examined by the Radiation Shielding Information Center. Volume 7

Energy Technology Data Exchange (ETDEWEB)

Trubey, D.K.; Roussin, R.W.; Gustin, A.B.

1983-08-01

An indexed bibliography of open literature selected by the Radiation Shielding Information Center since the previous volume was published in 1980 is presented in the area of radiation transport and shielding against radiation from nuclear reactors (fission and fusion), x-ray machines, radioisotopes, nuclear weapons (including fallout, and low energy accelerators (e.g., neutron generators). The bibliography was typeset from computer files constituting the RSIC Storage and Retrieval Information System. In addition to lists of literature titles by subject categories (accessions 6201-10156), an author index is given. Most of the literature selected for Volume VII was published in the years 1977 to 1981.

Bibliography, subject index, and author index of the literature examined by the Radiation Shielding Information Center. Volume 7

International Nuclear Information System (INIS)

Trubey, D.K.; Roussin, R.W.; Gustin, A.B.

1983-08-01

An indexed bibliography of open literature selected by the Radiation Shielding Information Center since the previous volume was published in 1980 is presented in the area of radiation transport and shielding against radiation from nuclear reactors (fission and fusion), x-ray machines, radioisotopes, nuclear weapons (including fallout, and low energy accelerators (e.g., neutron generators). The bibliography was typeset from computer files constituting the RSIC Storage and Retrieval Information System. In addition to lists of literature titles by subject categories (accessions 6201-10156), an author index is given. Most of the literature selected for Volume VII was published in the years 1977 to 1981

Triglyceride glucose-body mass index is effective in identifying nonalcoholic fatty liver disease in nonobese subjects.

Science.gov (United States)

Zhang, Shujun; Du, Tingting; Li, Mengni; Jia, Jing; Lu, Huiming; Lin, Xuan; Yu, Xuefeng

2017-06-01

Nonalcoholic fatty liver disease (NAFLD) is an increasingly common condition that is highly correlated with obesity; however, it is not uncommon among nonobese individuals. Triglyceride (TG) and glucose index combined with body mass index (TyG-BMI) has been proposed as a favorable marker of insulin resistance. We sought to investigate the effectiveness of TyG-BMI in identifying NAFLD in nonobese subjects.We conducted a cross-sectional study in a nonobese (BMI glucose, for identifying nonobese subjects at risk for NAFLD.In this study, the prevalence of NAFLD was over one-fifth in the nonobese population. TyG-BMI was an effective marker to detect NAFLD in nonobese subjects.

LP (a) levels and apo (a) phenotypes in urban black South African ...

African Journals Online (AJOL)

300 U/I), intermediate (300 - 700 UII) and high (> 700 UII) plasma Lp (a) ... Tygerberg Hospital, Tygerberg, W Cape ... up to 200-fold difference in Lp (a) concentrations.' In addition, ethnic .... An interesting observation was the large number of phenotypes, Le. ... sample of black Americans with a high-resolution SOS- agarose ...

LP 543-25: A Rare Low-mass Runaway Disk Star

Science.gov (United States)

de la Fuente Marcos, Raúl; de la Fuente Marcos, Carlos

2018-05-01

LP 543-25 or PSS 544-7 is a high proper-motion star located 458 pc from the Sun in the constellation of Canis Minor; it has been argued that it could be a candidate cannonball star ejected by a star cluster. Here, we revisit the issue of the kinematics of this interesting star using Gaia DR2. The heliocentric Galactic velocity components are (U, V, W) = (206, -289, 30) km/s; the corresponding Galactocentric Galactic velocity components show that LP 543-25 is moving in the Galactic plane and away from the Galactic Center at a rate of nearly 200 km/s, which is compatible with an origin in one of the multiple star clusters that inhabit the inner regions of the Milky Way. LP 543-25 appears to be a member of an elusive class of stars, the low-mass runaway stars. It is perhaps one of the closest and less massive runaway stars identified so far.

65 nm LP/GP mix low cost platform for multi-media wireless and consumer applications

Science.gov (United States)

Tavel, B.; Duriez, B.; Gwoziecki, R.; Basso, M. T.; Julien, C.; Ortolland, C.; Laplanche, Y.; Fox, R.; Sabouret, E.; Detcheverry, C.; Boeuf, F.; Morin, P.; Barge, D.; Bidaud, M.; Biénacel, J.; Garnier, P.; Cooper, K.; Chapon, J. D.; Trouiller, Y.; Belledent, J.; Broekaart, M.; Gouraud, P.; Denais, M.; Huard, V.; Rochereau, K.; Difrenza, R.; Planes, N.; Marin, M.; Boret, S.; Gloria, D.; Vanbergue, S.; Abramowitz, P.; Vishnubhotla, L.; Reber, D.; Stolk, P.; Woo, M.; Arnaud, F.

2006-04-01

A complete 65 nm CMOS platform, called LP/GP Mix, has been developed employing thick oxide transistor (IO), Low Power (LP) and General Purpose (GP) devices on the same chip. Dedicated to wireless multi-media and consumer applications, this new triple gate oxide platform is low cost (+1mask only) and saves over 35% of dynamic power with the use of the low operating voltage GP. The LP/GP mix shows competitive digital performance with a ring oscillator (FO = 1) speed equal to 7 ps per stage (GP) and 6T-SRAM static power lower than 10 pA/cell (LP). Compatible with mixed-signal design requirements, transistors show high voltage gain, low mismatch factor and low flicker noise. Moreover, to address mobile phone demands, excellent RF performance has been achieved with FT = 160 GHz for LP and 280 GHz for GP nMOS transistors.

Capped Lp approximations for the composite L0 regularization problem

OpenAIRE

Li, Qia; Zhang, Na

2017-01-01

The composite L0 function serves as a sparse regularizer in many applications. The algorithmic difficulty caused by the composite L0 regularization (the L0 norm composed with a linear mapping) is usually bypassed through approximating the L0 norm. We consider in this paper capped Lp approximations with $p>0$ for the composite L0 regularization problem. For each $p>0$, the capped Lp function converges to the L0 norm pointwisely as the approximation parameter tends to infinity. We point out tha...

Survival associated pathway identification with group Lp penalized global AUC maximization

Directory of Open Access Journals (Sweden)

Liu Zhenqiu

2010-08-01

Full Text Available Abstract It has been demonstrated that genes in a cell do not act independently. They interact with one another to complete certain biological processes or to implement certain molecular functions. How to incorporate biological pathways or functional groups into the model and identify survival associated gene pathways is still a challenging problem. In this paper, we propose a novel iterative gradient based method for survival analysis with group Lp penalized global AUC summary maximization. Unlike LASSO, Lp (p 1. We first extend Lp for individual gene identification to group Lp penalty for pathway selection, and then develop a novel iterative gradient algorithm for penalized global AUC summary maximization (IGGAUCS. This method incorporates the genetic pathways into global AUC summary maximization and identifies survival associated pathways instead of individual genes. The tuning parameters are determined using 10-fold cross validation with training data only. The prediction performance is evaluated using test data. We apply the proposed method to survival outcome analysis with gene expression profile and identify multiple pathways simultaneously. Experimental results with simulation and gene expression data demonstrate that the proposed procedures can be used for identifying important biological pathways that are related to survival phenotype and for building a parsimonious model for predicting the survival times.

State of the Art in LP-WAN Solutions for Industrial IoT Services.

Science.gov (United States)

Sanchez-Iborra, Ramon; Cano, Maria-Dolores

2016-05-17

The emergence of low-cost connected devices is enabling a new wave of sensorization services. These services can be highly leveraged in industrial applications. However, the technologies employed so far for managing this kind of system do not fully cover the strict requirements of industrial networks, especially those regarding energy efficiency. In this article a novel paradigm, called Low-Power Wide Area Networking (LP-WAN), is explored. By means of a cellular-type architecture, LP-WAN-based solutions aim at fulfilling the reliability and efficiency challenges posed by long-term industrial networks. Thus, the most prominent LP-WAN solutions are reviewed, identifying and discussing the pros and cons of each of them. The focus is also on examining the current deployment state of these platforms in Spain. Although LP-WAN systems are at early stages of development, they represent a promising alternative for boosting future industrial IIoT (Industrial Internet of Things) networks and services.

State of the Art in LP-WAN Solutions for Industrial IoT Services

Directory of Open Access Journals (Sweden)

Ramon Sanchez-Iborra

2016-05-01

Full Text Available The emergence of low-cost connected devices is enabling a new wave of sensorization services. These services can be highly leveraged in industrial applications. However, the technologies employed so far for managing this kind of system do not fully cover the strict requirements of industrial networks, especially those regarding energy efficiency. In this article a novel paradigm, called Low-Power Wide Area Networking (LP-WAN, is explored. By means of a cellular-type architecture, LP-WAN–based solutions aim at fulfilling the reliability and efficiency challenges posed by long-term industrial networks. Thus, the most prominent LP-WAN solutions are reviewed, identifying and discussing the pros and cons of each of them. The focus is also on examining the current deployment state of these platforms in Spain. Although LP-WAN systems are at early stages of development, they represent a promising alternative for boosting future industrial IIoT (Industrial Internet of Things networks and services.

Safety and immunogenicity of a meningococcal B bivalent rLP2086 vaccine in healthy toddlers aged 18-36 months: a phase 1 randomized-controlled clinical trial.

Science.gov (United States)

Marshall, Helen S; Richmond, Peter C; Nissen, Michael D; Jiang, Qin; Anderson, Annaliesa S; Jansen, Kathrin U; Reynolds, Graham; Ziegler, John B; Harris, Shannon L; Jones, Thomas R; Perez, John L

2012-10-01

A bivalent, recombinant, factor H-binding protein (rLP2086) vaccine was developed to protect against invasive Neisseria meningitidis serogroup B (MnB) in children and adolescents. Healthy toddlers (N = 99) were enrolled to 3 ascending dose-level cohorts (20, 60 or 200 μg). Within each cohort (n = 33), subjects were randomized to receive an initial formulation of the bivalent rLP2086 vaccine at 0, 1 and 6 months or hepatitis A vaccine/placebo control (2:1 ratio). Reactogenicity was assessed by parental reporting of local and systemic reactions using electronic diaries and reports of unsolicited adverse events. Immunogenicity was assessed by serum bactericidal activity assay using human complement and rLP2086-specific IgG binding. The vaccine was considered to be well tolerated. Tenderness was the most frequently reported local reaction. Upper respiratory tract infection was the most commonly reported adverse event and occurred more frequently in the control group. Three cases (200 μg dose) of severe erythema that did not interfere with limb movement were reported. Four toddlers developed fever >40.0°C, 3 in the 200 μg group and 1 in the 60 μg group. Postdose 3, seroconversion (serum bactericidal activity assay using human complement ≥4-fold rise from baseline) was observed in 61.1-88.9% of participants against MnB strains expressing LP2086 variants homologous or nearly homologous to vaccine antigens and 11.1-44.4% against MnB strains expressing heterologous LP2086 variants. Seroconversion was observed in 77.8-100% of participants against additional, exploratory MnB strains expressing vaccine-homologous or heterologous LP2086 variants. This study shows that the bivalent rLP2086 vaccine is well tolerated and immunogenic in toddlers.

Circulating and PBMC Lp-PLA2 associate differently with oxidative stress and subclinical inflammation in nonobese women (menopausal status.

Directory of Open Access Journals (Sweden)

Jean Kyung Paik

Full Text Available BACKGROUND: This study aimed to determine the association of lipoprotein-associated phospholipase A(2 (Lp-PLA(2 activity in circulation and peripheral blood mononuclear cells (PBMCs with inflammatory and oxidative stress markers in nonobese women and according to menopausal status. Lp-PLA(2 activity, a marker for cardiovascular risk is associated with inflammation and oxidative stress. METHODOLOGY/PRINCIPAL FINDINGS: Eighty postmenopausal women (53.0±4.05 yr and 96 premenopausal women (39.7±9.25 yr participated in this study. Lp-PLA(2 activities, interleukin (IL-6, tumor necrosis factor (TNF-α, and IL-1β in plasma as well as in PBMCs were measured. Plasma ox-LDL was also measured. Postmenopausal women demonstrated higher circulating levels of ox-LDL and IL-6, as well as IL-6, TNF-α, and IL-1β in PBMCs, than premenopausal women. In both groups, plasma Lp-PLA(2 activity positively correlated with Lp-PLA(2 activity in PBMCs and plasma ox-LDL. In premenopausal women, Lp-PLA(2 activities in plasma and PBMCs positively correlated with IL-6, TNF-α, and IL-1β in PBMCs. In postmenopausal women, plasma ox-LDL positively correlated with PBMC cytokine production. In subgroup analysis of postmenopausal women according to plasma ox-LDL level (median level: 48.715 U/L, a significant increase in Lp-PLA(2 activity in the plasma but not the PBMCs was found in the high ox-LDL subgroup. Plasma Lp-PLA(2 activity positively correlated with unstimulated PBMC Lp-PLA(2 activity in the low ox-LDL subgroup (r = 0.627, P<0.001, whereas in the high ox-LDL circulating Lp-PLA(2 activity positively correlated with plasma ox-LDL (r = 0.390, P = 0.014 but not with Lp-PLA(2 activity in PBMCs. CONCLUSIONS/SIGNIFICANCE: The lack of relation between circulating Lp-PLA(2 activity and Lp-PLA(2 activity in PBMCs was found in postmenopausal women with high ox-LDL. This may indicate other sources of circulating Lp-PLA(2 activity except PBMC in postmenopausal women

An LP-based heuristic for the fixed charge transportation problem

DEFF Research Database (Denmark)

Klose, Andreas

2007-01-01

The fixed charge transportation problem consists in finding a minimum cost network flow from a set of suppliers to a set of customers. Beside costs proportional to quantities transported, transportation costs also include a fixed charge. The paper describes a linear programming based heuristic...... approach for computing lower and upper bounds on the minimal cost. To this end, the LP relaxation is iteratively strengthened by means of adding cuts; in each iteration the current LP solution is then used to guide a local search heuristic. In addition to standard polyhedral cuts as lifted cover...

78 FR 62614 - Guttman Energy, Inc., PBF Holding Company LLC v. Buckeye Pipe Line Company, L.P., Laurel Pipe...

Science.gov (United States)

2013-10-22

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR14-4-000] Guttman Energy, Inc., PBF Holding Company LLC v. Buckeye Pipe Line Company, L.P., Laurel Pipe Line Company, L.P... complaint against Buckeye Pipe Line Company L.P. and Laurel Pipe Line Company L.P. (Respondents) challenging...

Influence of fruit drinks with or without lactobacillus Lp299v on the gastrointestinal uptake of paracetamol in man

DEFF Research Database (Denmark)

Akerman, Ulrika; Edvinsson, Lars

2009-01-01

BACKGROUND: Clinical observations have revealed that patients throw up undigested paracetamol tablets several hours following intake of rosehip drink with Lp299v (Proviva). The purpose of this study was to demonstrate if this translates into altered plasma levels of paracetamol in nineteen healthy...... subjects consuming 200 ml of water, Rose hip drink or Proviva together with 1.5 gram of paracetamol. FINDINGS: The concentration of paracetamol in plasma increased rapidly when the paracetamol-containing tablets were consumed together with water and after 30 minutes a median level of 90 mumol/l was reached...... (a 95% confidence interval of 57,161). The corresponding 30 minutes values of paracetamol levels in the presence of rosehip with or without Lp299v were 0 mumol/l (95% confidence intervals contain only zero for both rosehip treatments). There were significant differences in AUC, maximal paracetamol...

76 FR 29234 - Texas Eastern Transmission, LP; Notice of Request Under Blanket Authorization

Science.gov (United States)

2011-05-20

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-477-000] Texas Eastern Transmission, LP; Notice of Request Under Blanket Authorization Take notice that on May 10, 2011 Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in Docket No. CP11-477-000...

Advanced LP turbine installation at 1300 MW nuclear power station Unterweser

International Nuclear Information System (INIS)

Jacobsen, G.; Oeynhausen, H.; Termuehlen, H.

1991-01-01

This paper reports on Preussen Elektra AG's Unterweser power plant. The steam turbine-generator features a disk-type LP turbine rotor design developed in the late 1960's to early 1970's. This rotor design has been installed in 19 nuclear power plants. The 47 rotors in these plants have been in operation for an average of almost 10 years. The design of the 1970 vintage nuclear LP turbine rotors was based on extensive experience gained with disk-type rotors of fossil turbines built in the 1950's. When EPRI reported about corrosion cracking in nuclear LP turbines, a program was initiated by Siemens/KWU as original steam turbine supplier to ultrasonically inspect all their disk-type rotors in nuclear power plats. Indications on one rotor disk in the Unterweser plant was found. This single event was the only one found out of 310 disks inspected in nuclear power plants

77 FR 64767 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2012-10-23

... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... airworthiness directive (AD) for certain Gulfstream Aerospace LP (Type Certificate previously held by Israel... Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200 airplanes...

78 FR 47546 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2013-08-06

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model... Aviation Authority of Israel (CAAI), which is the aviation authority for Israel, has issued Israeli...

Bibliography, subject index, and author index of the literature examined by the Radiation Shielding Information Center (Reactor and Weapons Radiation Shielding)

International Nuclear Information System (INIS)

1978-01-01

An indexed bibliography is presented of literature selected by the Radiation Shielding Information Center since the previous volume was published in 1974 in the area of radiation transport and shielding against radiation from nuclear reactors, x-ray machines, radioisotopes, nuclear weapons (including fallout), and low-energy accelerators (e.g., neutron generators). In addition to lists of literature titles by subject categories (accessions 3501-4950), author and keyword indexes are given. Most of the literature selected for Vol. V was published in the years 1973 to 1976

Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a levels in African Americans.

Directory of Open Access Journals (Sweden)

Rahul C Deo

2011-01-01

Full Text Available Lipoprotein(a (Lp(a is an important causal cardiovascular risk factor, with serum Lp(a levels predicting atherosclerotic heart disease and genetic determinants of Lp(a levels showing association with myocardial infarction. Lp(a levels vary widely between populations, with African-derived populations having nearly 2-fold higher Lp(a levels than European Americans. We investigated the genetic basis of this difference in 4464 African Americans from the Jackson Heart Study (JHS using a panel of up to 1447 ancestry informative markers, allowing us to accurately estimate the African ancestry proportion of each individual at each position in the genome. In an unbiased genome-wide admixture scan for frequency-differentiated genetic determinants of Lp(a level, we found a convincing peak (LOD = 13.6 at 6q25.3, which spans the LPA locus. Dense fine-mapping of the LPA locus identified a number of strongly associated, common biallelic SNPs, a subset of which can account for up to 7% of the variation in Lp(a level, as well as >70% of the African-European population differences in Lp(a level. We replicated the association of the most strongly associated SNP, rs9457951 (p = 6 × 10(-22, 27% change in Lp(a per allele, ∼5% of Lp(a variance explained in JHS, in 1,726 African Americans from the Dallas Heart Study and found an even stronger association after adjustment for the kringle(IV repeat copy number. Despite the strong association with Lp(a levels, we find no association of any LPA SNP with incident coronary heart disease in 3,225 African Americans from the Atherosclerosis Risk in Communities Study.

75 FR 28485 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2010-05-21

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39... previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream 100 airplanes; and Model Astra SPX and...

Smell of danger: an analysis of LP-gas odorization

Energy Technology Data Exchange (ETDEWEB)

Cain, W.S.; Turk, A.

1985-03-01

LP-gas derives warning properties from the odorants ethyl mercaptan or thiophane. Laboratory tests have implied that the average person has the ability to smell the odors before leaking LP-gas reaches one-fifth its lower limit of flammability. Generally, however, laboratory tests ignore or discard persons with a poor sense of smell, especially the elderly and persons with certain types of hyposmia. Some persons who apparently can smell the warning agents when directed may otherwise fail to notice or identify them. Elderly men seem particularly vulnerable to instances of incidental anosmia and olfactory agnosia. Psychophysical testing of the warning agents has been rather unsophisticated. There exists neither a standard protocol for testing nor adequate specification of the perceptual properties that might make one warning agent better than another. Without such developments, improvement in warning agents will fail to occur. Possible improvements include increases in concentration, the use of blends to insure more uniform delivery of agent and, to decrease the perceptual vulnerability of relatively insensitive people, use of agents with favorable psychophysical (stimulus-response) functions and use of agents with favorable adaptation characteristics. Even without a change in existing products, it seems advisable to learn more about the vulnerability of LP-gas users and to employ educational means to reduce risks.

Comparative genome analysis of Lactobacillus plantarum GB-LP3 provides candidates of survival-related genetic factors.

Science.gov (United States)

Jeon, Soomin; Jung, Jaehoon; Kim, Kwondo; Yoo, DongAhn; Lee, Chanho; Kang, Jungsun; Cho, Kyungjin; Kang, Dae-Kyung; Kwak, Woori; Yoon, Sook Hee; Kim, Heebal; Cho, Seoae

2017-09-01

Lactobacillus plantarum is found in various environmental niches such as in the gastrointestinal tract of an animal host or a fermented food. This species isolated from a certain environment is known to possess a variety of properties according to inhabited environment's adaptation. However, a causal relationship of a genetic factor and phenotype affected by a specific environment has not been systematically comprehended. L. plantarum GB-LP3 strain was isolated from Korean traditional fermented vegetable and the whole genome of GB-LP3 was sequenced. Comparative genome analysis of GB-LP3, with other 14 L. plantarum strains, was conducted. In addition, genomic island regions were investigated. The assembled whole GB-LP3 genome contained a single circular chromosome of 3,206,111bp with the GC content of 44.7%. In the phylogenetic tree analysis, GB-LP3 was in the closest distance from ZJ316. The genomes of GB-LP3 and ZJ316 have the high level of synteny. Functional genes that are related to prophage, bacteriocin, and quorum sensing were found through comparative genomic analysis with ZJ316 and investigation of genomic islands. dN/dS analysis identified that the gene coding for phosphonate ABC transporter ATP-binding protein is evolutionarily accelerated in GB-LP3. Our study found that potential candidate genes that are affected by environmental adaptation in Korea traditional fermented vegetable. Copyright © 2017. Published by Elsevier B.V.

A new LP formulation of the admission control problem modelled as an MDP under average reward criterion

Science.gov (United States)

Pietrabissa, Antonio

2011-12-01

The admission control problem can be modelled as a Markov decision process (MDP) under the average cost criterion and formulated as a linear programming (LP) problem. The LP formulation is attractive in the present and future communication networks, which support an increasing number of classes of service, since it can be used to explicitly control class-level requirements, such as class blocking probabilities. On the other hand, the LP formulation suffers from scalability problems as the number C of classes increases. This article proposes a new LP formulation, which, even if it does not introduce any approximation, is much more scalable: the problem size reduction with respect to the standard LP formulation is O((C + 1)2/2 C ). Theoretical and numerical simulation results prove the effectiveness of the proposed approach.

Long Period (LP) volcanic earthquake source location at Merapi volcano by using dense array technics

Science.gov (United States)

Metaxian, Jean Philippe; Budi Santoso, Agus; Laurin, Antoine; Subandriyo, Subandriyo; Widyoyudo, Wiku; Arshab, Ghofar

2015-04-01

Since 2010, Merapi shows unusual activity compared to last decades. Powerful phreatic explosions are observed; some of them are preceded by LP signals. In the literature, LP seismicity is thought to be originated within the fluid, and therefore to be representative of the pressurization state of the volcano plumbing system. Another model suggests that LP events are caused by slow, quasi-brittle, low stress-drop failure driven by transient upper-edifice deformations. Knowledge of the spatial distribution of LP events is fundamental for better understanding the physical processes occurring in the conduit, as well as for the monitoring and the improvement of eruption forecasting. LP events recorded at Merapi have a spectral content dominated by frequencies between 0.8 and 3 Hz. To locate the source of these events, we installed a seismic antenna composed of 4 broadband CMG-6TD Güralp stations. This network has an aperture of 300 m. It is located on the site of Pasarbubar, between 500 and 800 m from the crater rim. Two multi-parameter stations (seismic, tiltmeter, S-P) located in the same area, equipped with broadband CMG-40T Güralp sensors may also be used to complete the data of the antenna. The source of LP events is located by using different approaches. In the first one, we used a method based on the measurement of the time delays between the early beginnings of LP events for each array receiver. The observed differences of time delays obtained for each pair of receivers are compared to theoretical values calculated from the travel times computed between grid nodes, which are positioned in the structure, and each receiver. In a second approach, we estimate the slowness vector by using MUSIC algorithm applied to 3-components data. From the slowness vector, we deduce the back-azimuth and the incident angle, which give an estimation of LP source depth in the conduit. This work is part of the Domerapi project funded by French Agence Nationale de la Recherche (https

77 FR 44113 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2012-07-27

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Aerospace LP (Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150... to the manufacturer. This action was prompted by a report from the Civil Aviation Authority of Israel...

Lr-Lp Stability of the Incompressible Flows with Nonzero Far-Field Velocity

Directory of Open Access Journals (Sweden)

Jaiok Roh

2011-01-01

Full Text Available We consider the stability of stationary solutions w for the exterior Navier-Stokes flows with a nonzero constant velocity u∞ at infinity. For u∞=0 with nonzero stationary solution w, Chen (1993, Kozono and Ogawa (1994, and Borchers and Miyakawa (1995 have studied the temporal stability in Lp spaces for 11 and obtain Lr-Lp stability as Kozono and Ogawa and Borchers and Miyakawa obtained for u∞=0.

75 FR 8921 - Grant of Authority for Subzone Status; Brightpoint North America L.P. (Cell Phone Kitting and...

Science.gov (United States)

2010-02-26

... Status; Brightpoint North America L.P. (Cell Phone Kitting and Distribution) Indianapolis, IN Pursuant to... the cell phone kitting and distribution facilities of Brightpoint North America L.P., located in... cell phones at the facilities of Brightpoint North America L.P., located in Plainfield, Indiana...

ChLpMab-23: Cancer-Specific Human-Mouse Chimeric Anti-Podoplanin Antibody Exhibits Antitumor Activity via Antibody-Dependent Cellular Cytotoxicity.

Science.gov (United States)

Kaneko, Mika K; Nakamura, Takuro; Kunita, Akiko; Fukayama, Masashi; Abe, Shinji; Nishioka, Yasuhiko; Yamada, Shinji; Yanaka, Miyuki; Saidoh, Noriko; Yoshida, Kanae; Fujii, Yuki; Ogasawara, Satoshi; Kato, Yukinari

2017-06-01

Podoplanin is expressed in many cancers, including oral cancers and brain tumors. The interaction between podoplanin and its receptor C-type lectin-like receptor 2 (CLEC-2) has been reported to be involved in cancer metastasis and tumor malignancy. We previously established many monoclonal antibodies (mAbs) against human podoplanin using the cancer-specific mAb (CasMab) technology. LpMab-23 (IgG 1 , kappa), one of the mouse anti-podoplanin mAbs, was shown to be a CasMab. However, we have not shown the usefulness of LpMab-23 for antibody therapy against podoplanin-expressing cancers. In this study, we first determined the minimum epitope of LpMab-23 and revealed that Gly54-Leu64 peptide, especially Gly54, Thr55, Ser56, Glu57, Asp58, Arg59, Tyr60, and Leu64 of podoplanin, is a critical epitope of LpMab-23. We further produced human-mouse chimeric LpMab-23 (chLpMab-23) and investigated whether chLpMab-23 exerts antibody-dependent cellular cytotoxicity (ADCC) and antitumor activity. In flow cytometry, chLpMab-23 showed high sensitivity against a podoplanin-expressing glioblastoma cell line, LN319, and an oral cancer cell line, HSC-2. chLpMab-23 also showed ADCC activity against podoplanin-expressing CHO cells (CHO/podoplanin). In xenograft models with HSC-2 and CHO/podoplanin, chLpMab-23 exerts antitumor activity using human natural killer cells, indicating that chLpMab-23 could be useful for antibody therapy against podoplanin-expressing cancers.

List of U.S. Army Research Institute Research and Technical Publications for Public Release/Unlimited Distribution. Fiscal Year 2007 (October 1, 2006 to September 30, 2007) With Author Index and Report Titles and Subject Terms Index

Science.gov (United States)

2008-04-01

Year 2007 October 1, 2006 to September 30, 2007 With Author Index and Report Titles and Subject Terms Index United States Army Research Institute for...Fiscal Year 2007 October 1, 2006 to September 30, 2007 With Author Index and Report Titles and Subject Terms Index CONTENTS Page Introduction...39 Author Index .................................................................................................................. 39

Estimating the Population Impact of Lp(a) Lowering on the Incidence of Myocardial Infarction and Aortic Stenosis

DEFF Research Database (Denmark)

Afshar, Mehdi; Kamstrup, Pia R; Williams, Ken

2016-01-01

OBJECTIVE: High lipoprotein(a) (Lp[a]) is the most common genetic dyslipidemia and is a causal factor for myocardial infarction (MI) and aortic stenosis (AS). We sought to estimate the population impact of Lp(a) lowering that could be achieved in primary prevention using the therapies in developm......OBJECTIVE: High lipoprotein(a) (Lp[a]) is the most common genetic dyslipidemia and is a causal factor for myocardial infarction (MI) and aortic stenosis (AS). We sought to estimate the population impact of Lp(a) lowering that could be achieved in primary prevention using the therapies...... as measures of the population impact. For MI, the event rate was 4.0% versus 2.8% for high versus low Lp(a) (relative risk, 1.46; 95% confidence interval [CI], 1.45-1.46). The attributable risk was 1.26% (95% CI, 1.24-1.27), corresponding to 31.3% (95% CI, 31.0-31.7) of the excess MI risk in those with high...... and 7.8% for AS. CONCLUSIONS: Lp(a) lowering among the top 20% of the population distribution for Lp(a) could prevent 1 in 14 cases of MI and 1 in 7 cases of AS, suggesting a major impact on reducing the burden of cardiovascular disease. Targeting the top 10% could prevent 1 in 20 MI cases and 1 in 12...

78 FR 11639 - Houston Pipe Line Company LP; Notice of Petition for Rate Approval

Science.gov (United States)

2013-02-19

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR13-31-000] Houston Pipe Line Company LP; Notice of Petition for Rate Approval Take notice that on February 1, 2013, Houston Pipe Line Company LP (HPL) filed for approval of rates for transportation service pursuant to section...

TRAC-PF1 code assessment using OECD LOFT LP-FP-1 experiment

International Nuclear Information System (INIS)

Barbero, F.J.

1992-04-01

This report assesses thermal-hydraulic aspects of LOFT LP-FP-1 experiment making use of TRAC-PF1/MOD1. LP-FP-1 experiment studies the system thermal-hydraulic and core thermal response for initial and boundary conditions similar to a large-break design basis LOCA leading to fission product release from the fuel cladding gap region. It also assesses the fission product retention effectiveness of the PWR-ECCS in best estimate conditions

THE RUNAWAY WHITE DWARF LP400-22 HAS A COMPANION

International Nuclear Information System (INIS)

Kilic, Mukremin; Brown, Warren R.; Kenyon, S. J.; Allende Prieto, Carlos; Swift, B.; Liebert, J.; Agueeros, M. A.

2009-01-01

We report the detection of a radial velocity companion to the extremely low-mass white dwarf (WD) LP400-22. The radial velocity of the WD shows variations with a semiamplitude of 119 km s -1 and a 0.98776 day period, which implies a companion mass of M ≥ 0.37 M sun . The optical photometry rules out a main-sequence companion. Thus the invisible companion is another WD or a neutron star. Using proper-motion measurements and the radial velocity of the binary system, we find that it has an unusual Galactic orbit. LP400-22 is moving away from the Galactic center with a velocity of 396 ± 43 km s -1 , which is very difficult to explain by supernova runaway ejection mechanisms. Dynamical interactions with a massive black hole like that in the Galactic center can in principle explain its peculiar velocity, if the progenitor was a triple star system comprised of a close binary and a distant tertiary companion. Until better proper motions become available, we consider LP400-22 to be most likely a halo star with a very unusual orbit.

LP-tee pikeneb Tartust Pärnuni / Sirje Pärismaa

Index Scriptorium Estoniae

Pärismaa, Sirje, 1958-

2015-01-01

Norrast pärit tõenduspõhist koostöökultuuri arendava LP-mudeliga (learning environment and pedagogical analysis) on liitumas seitse kooli Pärnust, Viljandist, Puhjast, Tartust ning kolm lasteaeda

Cytoarchitecture of the human lateral occipital cortex: mapping of two extrastriate areas hOc4la and hOc4lp.

Science.gov (United States)

Malikovic, Aleksandar; Amunts, Katrin; Schleicher, Axel; Mohlberg, Hartmut; Kujovic, Milenko; Palomero-Gallagher, Nicola; Eickhoff, Simon B; Zilles, Karl

2016-05-01

The microstructural correlates of the functional segregation of the human lateral occipital cortex are largely unknown. Therefore, we analyzed the cytoarchitecture of this region in ten human post-mortem brains using an observer-independent and statistically testable parcellation method to define the position and extent of areas in the lateral occipital cortex. Two new cytoarchitectonic areas were found: an anterior area hOc4la and a posterior area hOc4lp. hOc4la was located behind the anterior occipital sulcus in rostral and ventral portions of this region where it occupies the anterior third of the middle and inferior lateral occipital gyri. hOc4lp was found in caudal and dorsal portions of this region where it extends along the superior and middle lateral occipital gyri. The cytoarchitectonic areas were registered to 3D reconstructions of the corresponding brains, which were subsequently spatially normalized to the Montreal Neurological Institute reference space. Continuous probabilistic maps of both areas based on the analysis of ten brains were generated to characterize their inter-subject variability in location and size. The maps of hOc4la and hOc4lp were then used as seeds for meta-analytic connectivity modeling and quantitative functional decoding to identify their co-activation patterns and assignment to functional domains. Convergent evidence from their location, topography, size, functional domains and connectivity indicates that hOc4la and hOc4lp are the potential anatomical correlates of the functionally defined lateral occipital areas LO-1 and LO-2.

75 FR 14644 - Gemini Investors IV, L.P., Notice Seeking Exemption Under Section 312 of the Small Business...

Science.gov (United States)

2010-03-26

... SMALL BUSINESS ADMINISTRATION [License No. 01/01-0410] Gemini Investors IV, L.P., Notice Seeking... given that Gemini Investors IV, L.P., 20 William Street, Wellesley, MA 02481, a Federal Licensee under... Regulations (13 CFR 107.730). Gemini Investors IV, L.P. proposes to provide equity and debt financing to...

Lithium in LP944-20

Science.gov (United States)

Pavlenko, Ya. V.; Jones, H. R. A.; Martín, E. L.; Guenther, E.; Kenworthy, M. A.; Zapatero Osorio, M. R.

2007-09-01

We present a new estimate of the lithium abundance in the atmosphere of the brown dwarf LP944-20. Our analysis is based on a self-consistent analysis of low-, intermediate- and high-resolution optical and near-infrared spectra. We obtain logN(Li) = 3.25 +/- 0.25 using fits of our synthetic spectra to the LiI resonance line doublet profiles observed with Very Large Telescope/Ultraviolet-Visual Echelle Spectrograph (VLT/UVES) and Anglo-Australian Telescope/Segmented Pupil/Image Reformatting Array of Lenslets (AAT/SPIRAL). This lithium abundance is over two orders of magnitude larger than previous estimates in the literature. In order to obtain good fits of the resonance lines of KI and RbI and better fits to the TiO molecular absorption around the LiI resonance line, we invoke a semi-empirical model atmosphere with the dusty clouds located above the photosphere. The lithium abundance, however, is not changed by the effects of the dusty clouds. We discuss the implications of our estimate of the lithium abundance in LP944-20 for the understanding of the properties of this benchmark brown dwarf. Based on observations obtained on the European Southern Observatory at Cerro Paranal, Chile, in programs 68.C-0063(A) and 072.C-0110(B), the Anglo-Australian Telescope at Siding Springs Observatory during commissioning observations for SPIRAL (Segmented Pupil/Image Reformatting Array of Lenslets) instrument and the Keck Observatory in Mauna Kea, Hawaii. E-mail: yp@mao.kiev.ua

76 FR 41041 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane, Interaction of Systems...

Science.gov (United States)

2011-07-13

... Conditions No. 25-439-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane, Interaction... special conditions are issued for the Gulfstream Aerospace LP (GALP) Model G250 airplane. This airplane...

The lysine-peptoid hybrid LP5 maintain activity under physiological conditions and affects virulence gene expression in Staphylococcus aureus

DEFF Research Database (Denmark)

Gottschalk, Sanne; Ingmer, Hanne; Thomsen, Line E.

2016-01-01

The antimicrobial peptide, LP5, is a lysine-peptoid hybrid, with antimicrobial activity against clinically relevant bacteria. Here, we investigated how various environmental conditions affect the antimicrobial activity of LP5 against Staphylococcus aureus (S. aureus). We found that LP5 maintained...

Statistical Review of Global LP Gas 2002

International Nuclear Information System (INIS)

2002-01-01

This review provides essential production and consumption data from 1991 through 2001. A detailed breakdown of supply and sector demand is given for the year 2001 and historic data on international trade, shipping and pricing is also shown. Statistics pertaining to auto-gas are also included in this edition of Statistical Review of Global LP Gas 2001. (author)

Statistical review of global LP gas 2001

International Nuclear Information System (INIS)

2001-01-01

This review provides essential production and consumption data from 1990 through 2000. A more detailed breakdown of supply and sector demand is given for the year 2000 and historic data on international trade, shipping and pricing is also shown. Statistics pertaining to auto-gas are also included in this edition of Statistical Review of Global LP Gas 2001. (author)

Novel Monoclonal Antibody LpMab-17 Developed by CasMab Technology Distinguishes Human Podoplanin from Monkey Podoplanin.

Science.gov (United States)

Kato, Yukinari; Ogasawara, Satoshi; Oki, Hiroharu; Honma, Ryusuke; Takagi, Michiaki; Fujii, Yuki; Nakamura, Takuro; Saidoh, Noriko; Kanno, Hazuki; Umetsu, Mitsuo; Kamata, Satoshi; Kubo, Hiroshi; Yamada, Mitsuhiro; Sawa, Yoshihiko; Morita, Kei-Ichi; Harada, Hiroyuki; Suzuki, Hiroyoshi; Kaneko, Mika Kato

2016-04-01

Podoplanin (PDPN) is a type-I transmembrane sialoglycoprotein, which possesses a platelet aggregation-stimulating (PLAG) domain in its N-terminus. Among the three PLAG domains, O-glycan on Thr52 of PLAG3 is critical for the binding with C-type lectin-like receptor-2 (CLEC-2) and is essential for platelet-aggregating activity of PDPN. Although many anti-PDPN monoclonal antibodies (mAbs) have been established, almost all mAbs bind to PLAG domains. We recently established CasMab technology to produce mAbs against membranous proteins. Using CasMab technology, we produced a novel anti-PDPN mAb, LpMab-17, which binds to non-PLAG domains. LpMab-17 clearly detected endogenous PDPN of cancer cells and normal cells in Western-blot, flow cytometry, and immunohistochemistry. LpMab-17 recognized glycan-deficient PDPN in flow cytometry, indicating that the interaction between LpMab-17 and PDPN is independent of its glycosylation. The minimum epitope of LpMab-17 was identified as Gly77-Asp82 of PDPN using enzyme-linked immunosorbent assay. Of interest, LpMab-17 did not bind to monkey PDPN, whereas the homology is 94% between human PDPN and monkey PDPN, indicating that the epitope of LpMab-17 is unique compared with the other anti-PDPN mAbs. The combination of different epitope-possessing mAbs could be advantageous for the PDPN-targeting diagnosis or therapy.

75 FR 51451 - Erie Boulevard Hydropower, L.P.; Notice of Intent To File License Application, Filing of Pre...

Science.gov (United States)

2010-08-20

... Hydropower, L.P.; Notice of Intent To File License Application, Filing of Pre-Application Document, and.... Project No.: 7320-040. c. Dated Filed: June 29, 2010. d. Submitted By: Erie Boulevard Hydropower, L.P. e...: John Mudre at (202) 502-8902; or e-mail at [email protected] . j. Erie Boulevard Hydropower, L.P...

Poly-(R)-3-hydroxybutyrates (PHB) are Atherogenic Components of Lipoprotein Lp(a).

Science.gov (United States)

Reusch, Rosetta N

2015-12-01

The hypothesis is that poly-(R)-3-hydroxybutyrates (PHB), linear polymers of the ketone body, R-3-hydroxybutyrate (R-3HB), are atherogenic components of lipoprotein Lp(a). PHB are universal constituents of biological cells and are thus components of all foods. Medium chain-length PHB (PHB (PHB are highly insoluble in water, but soluble in lipids in which they exhibit a high intrinsic viscosity. They have a higher density than other cellular lipids and they are very adhesive, i.e. they engage in multiple noncovalent interactions with other molecules and salts via hydrogen, hydrophobic and coordinate bonds, thus producing insoluble deposits. Following digestive processes, PHB enter the circulation in chylomicrons and very low density lipoproteins (VLDL). The majority of the PHB (>70%) are absorbed by albumin, which transports them to the liver for disposal. When the amount of PHB in the diet exceed the capacity of albumin to safely remove them from the circulation, the excess PHB remain in the lipid core of LDL particles that become constituents of lipoprotein Lp(a), and contribute to the formation of arterial deposits. In summary, the presence of PHB – water-insoluble, dense, viscous, adhesive polymers – in the lipid cores of the LDL moieties of Lp(a) particles supports the hypothesis that PHB are atherogenic components of Lp(a).

Bibliography, subject index, and author index of the literature examined by the radiation shielding information center. Volume 6. Reactor and weapons radiation shielding

International Nuclear Information System (INIS)

1980-05-01

An indexed bibliography is presented of literature selected by the Radiation Shielding Information Center since the previous volume was published in 1978 in the area of radiation transport and shielding against radiation from nuclear reactors, x-ray machines, radioisotopes, nuclear weapons (including fallout), and low energy accelerators (e.g., neutron generators). The bibliography was typeset from data processed by computer from magnetic tape files. In addition to lists of literature titles by subject categories (accessions 4951-6200), an author index is given

Univariate Lp and ɭ p Averaging, 0 < p < 1, in Polynomial Time by Utilization of Statistical Structure

Directory of Open Access Journals (Sweden)

John E. Lavery

2012-10-01

Full Text Available We present evidence that one can calculate generically combinatorially expensive Lp and lp averages, 0 < p < 1, in polynomial time by restricting the data to come from a wide class of statistical distributions. Our approach differs from the approaches in the previous literature, which are based on a priori sparsity requirements or on accepting a local minimum as a replacement for a global minimum. The functionals by which Lp averages are calculated are not convex but are radially monotonic and the functionals by which lp averages are calculated are nearly so, which are the keys to solvability in polynomial time. Analytical results for symmetric, radially monotonic univariate distributions are presented. An algorithm for univariate lp averaging is presented. Computational results for a Gaussian distribution, a class of symmetric heavy-tailed distributions and a class of asymmetric heavy-tailed distributions are presented. Many phenomena in human-based areas are increasingly known to be represented by data that have large numbers of outliers and belong to very heavy-tailed distributions. When tails of distributions are so heavy that even medians (L1 and l1 averages do not exist, one needs to consider using lp minimization principles with 0 < p < 1.

76 FR 2432 - Bancshares Capital, L.P.; Notice of Surrender Under 13 CFR 107.1900

Science.gov (United States)

2011-01-13

... SMALL BUSINESS ADMINISTRATION [License No. 10/10-0194] Bancshares Capital, L.P.; Notice of Surrender Under 13 CFR 107.1900 Pursuant to the authority granted to the United States Small Business... 107.1900 of the Small Business Administration Rules and Regulations Bancshares Capital, L.P., 16118...

75 FR 35017 - Brookfield Energy Marketing LP; Supplemental Notice That Initial Market-Based Rate Filing...

Science.gov (United States)

2010-06-21

... Energy Marketing LP; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... proceeding of Brookfield Energy Marketing LP's application for market-based rate authority, with an... protests and interventions in lieu of paper, using the FERC Online links at http://www.ferc.gov . To...

Validation of ozone profile retrievals derived from the OMPS LP version 2.5 algorithm against correlative satellite measurements

Science.gov (United States)

Kramarova, Natalya A.; Bhartia, Pawan K.; Jaross, Glen; Moy, Leslie; Xu, Philippe; Chen, Zhong; DeLand, Matthew; Froidevaux, Lucien; Livesey, Nathaniel; Degenstein, Douglas; Bourassa, Adam; Walker, Kaley A.; Sheese, Patrick

2018-05-01

The Limb Profiler (LP) is a part of the Ozone Mapping and Profiler Suite launched on board of the Suomi NPP satellite in October 2011. The LP measures solar radiation scattered from the atmospheric limb in ultraviolet and visible spectral ranges between the surface and 80 km. These measurements of scattered solar radiances allow for the retrieval of ozone profiles from cloud tops up to 55 km. The LP started operational observations in April 2012. In this study we evaluate more than 5.5 years of ozone profile measurements from the OMPS LP processed with the new NASA GSFC version 2.5 retrieval algorithm. We provide a brief description of the key changes that had been implemented in this new algorithm, including a pointing correction, new cloud height detection, explicit aerosol correction and a reduction of the number of wavelengths used in the retrievals. The OMPS LP ozone retrievals have been compared with independent satellite profile measurements obtained from the Aura Microwave Limb Sounder (MLS), Atmospheric Chemistry Experiment Fourier Transform Spectrometer (ACE-FTS) and Odin Optical Spectrograph and InfraRed Imaging System (OSIRIS). We document observed biases and seasonal differences and evaluate the stability of the version 2.5 ozone record over 5.5 years. Our analysis indicates that the mean differences between LP and correlative measurements are well within required ±10 % between 18 and 42 km. In the upper stratosphere and lower mesosphere (> 43 km) LP tends to have a negative bias. We find larger biases in the lower stratosphere and upper troposphere, but LP ozone retrievals have significantly improved in version 2.5 compared to version 2 due to the implemented aerosol correction. In the northern high latitudes we observe larger biases between 20 and 32 km due to the remaining thermal sensitivity issue. Our analysis shows that LP ozone retrievals agree well with the correlative satellite observations in characterizing vertical, spatial and temporal

Comparison of a lightweight polypropylene mesh (Optilene® LP) and a large-pore knitted PTFE mesh (GORE® INFINIT® mesh)--Biocompatibility in a standardized endoscopic extraperitoneal hernia model.

Science.gov (United States)

Jacob, Dietmar A; Schug-Pass, Christine; Sommerer, Florian; Tannapfel, Andrea; Lippert, Hans; Köckerling, Ferdinand

2012-02-01

The use of a mesh with good biocompatibility properties is of decisive importance for the avoidance of recurrences and chronic pain in endoscopic hernia repair surgery. As we know from numerous experiments and clinical experience, large-pore, lightweight polypropylene meshes possess the best biocompatibility. However, large-pore meshes of different polymers may be used as well and might be an alternative solution. Utilizing a totally extraperitoneal technique in an established animal model, 20 domestic pigs were implanted with either a lightweight large-pore polypropylene (PP) mesh (Optilene® LP) or a medium-weight large-pore knitted polytetrafluorethylene (PTFE) mesh (GORE® INFINIT® mesh). After 94 days, the pigs were sacrificed and postmortem diagnostic laparoscopy was performed, followed by explantation of the specimens for macroscopic, histological and immunohistochemical evaluation. The mean mesh shrinkage rate was 14.2% for Optilene® LP vs. 24.7% for INFINIT® mesh (p = 0.017). The partial volume of the inflammatory cells was 11.2% for Optilene® LP vs. 13.9% for INFINIT (n.s.). CD68 was significantly higher for INFINIT (11.8% vs. 5.6%, p = 0.007). The markers of cell turnover, namely Ki67 and the apoptotic index, were comparable at 6.4% vs. 12.4% (n.s.) and 1.6% vs. 2.0% (n.s.). In the extracellular matrix, TGF-β was 35.4% for Optilene® LP and 31.0% for INFINIT® (n.s.). Collagen I (pos/300 μm) deposits were 117.8 and 114.9, respectively. In our experimental examinations, Optilene® LP and INFINIT® showed a comparable biocompatibility in terms of chronic inflammatory reaction; however, the shrinkage rate was significantly higher for INFINIT® after 3 months. The higher shrinkage rate of INFINIT® should be taken into account when choosing the mesh size for an adequate hernia overlap.

Modulation of gut barrier function in patients with obstructive jaundice using probiotic LP299v.

Science.gov (United States)

Jones, Claire; Badger, Stephen A; Regan, Mark; Clements, Barry W; Diamond, Tom; Parks, Rowan W; Taylor, Mark A

2013-12-01

This study aimed to determine the effect of LP229v on intestinal permeability and tumour necrosis factor (TNF) p55 receptor concentrations in patients with obstructive jaundice undergoing biliary drainage. Patients undergoing biliary drainage were recruited and randomized into three groups to receive Lactobacillus plantarum 299v (LP299v), inactivated LP299v (placebo) or water. These were administered daily at noon until 7 days after biliary drainage. Intestinal permeability was measured using the lactulose/mannitol (L/M) dual sugar absorption test on admission, the day before biliary drainage and on days 1 and 7 after biliary drainage. Blood and urine were collected to determine the L/M ratio and the TNF p55 receptor levels at each time point. A total of 25 patients were recruited; 12 had choledocholithiasis and nine had a periampullary tumour. Open surgical biliary drainage was performed in nine patients, endoscopic retrograde cholangiopancreatography in 12 and percutaneous transhepatic cholangiography in two. Five patients received LP299v, five received placebo and seven, water. The median L/M ratio was 0.035 (0.018-0.065) at baseline. No difference existed between the groups on admission, before drainage and on day 7 after drainage (P=0.59, 0.175 and 0.61, respectively). The L/M ratio was lower in the LP299v group on day 1 after drainage [0.01 (0.01) vs. 0.18 (0.03-0.3) and 0.11 (0.07-0.14); P=0.37]. Although the TNF p55 receptor levels were lower on day 1 after drainage in the LP299v group (15.3 vs. 30.9 vs. 82.7 ng/ml; P=0.43), the concentration at the four time points was similar (P=0.24, 0.96, 0.43 and 0.68). Pretreatment with probiotic LP299v improves intestinal permeability after biliary drainage and attenuates the inflammatory response. However, a larger multicentre trial is required to determine the effect on clinical outcome.

Who's who in the LP-Gas industry

International Nuclear Information System (INIS)

Anon.

1997-01-01

All pertinent information about the most important North American companies in the LP-Gas industry are listed alphabetically in an easy-to-use directory. A total of 395 listings are included. Besides company names and addresses, other information such as key personnel and products produced and marketed to affiliated companies, and a list of other services offered by each company are also provided

Dødshjælp, drabsforbud og deontologi

DEFF Research Database (Denmark)

Dige, Morten

2008-01-01

Et velkendt argument imod aktiv dødshjælp har det deontologiske forbud mod drab eller pligten til ikke at slå ihjel som en central præmis. Sådanne deontologiske argumenter spiller en fremtrædende rolle i nylige publikationer fra Det Etiske Råd. For at gælde ukvalificeret, må disse argumenter imid...

76 FR 12103 - Erie Boulevard Hydropower, L.P; Notice of Settlement Agreement and Soliciting Comments

Science.gov (United States)

2011-03-04

... Hydropower, L.P; Notice of Settlement Agreement and Soliciting Comments Take notice that the following... Boulevard Hydropower, L.P. e. Location: The existing multi-development project is located on the Oswegatchie... 791 (a)-825(r) h. Applicant Contact: Daniel Daoust, Erie Boulevard Hydropower, 33 West 1st Street...

Bibliography, subject index, and author index of the literature examined by the Radiation Shielding Information Center (Reactor and Weapons Radiation Shielding). [1973--1976

Energy Technology Data Exchange (ETDEWEB)

1978-01-01

An indexed bibliography is presented of literature selected by the Radiation Shielding Information Center since the previous volume was published in 1974 in the area of radiation transport and shielding against radiation from nuclear reactors, x-ray machines, radioisotopes, nuclear weapons (including fallout), and low-energy accelerators (e.g., neutron generators). In addition to lists of literature titles by subject categories (accessions 3501-4950), author and keyword indexes are given. Most of the literature selected for Vol. V was published in the years 1973 to 1976.

Differences in time-domain and spectral indexes of skin-surface laser-Doppler signals between controls and breast-cancer subjects.

Science.gov (United States)

Hsiu, Hsin; Chen, Chao-Tsung; Hung, Shuo-Hui; Chen, Guan-Zhang; Huang, Yu-Ling

2018-04-13

There is an urgent need to improve the early diagnosis of breast cancer. The present study applied spectral and beat-to-beat analyses to laser-Doppler (LDF) data sequences measured on the skin surface on the back of the right hands, with the aim of comparing the different peripheral microcirculatory-blood-flow (MBF) perfusion condition between breast-cancer and control subjects. ECG and LDF signals were obtained simultaneously and noninvasively from 23 breast-cancer patients and 23 age-matched control subjects. Time-domain beat-to-beat indexes and their variability parameters were calculated. Spectral indexes were calculated using the Morlet wavelet transform. The beat-to-beat LDF pulse width and its variability were significantly smaller in cancer patients than in the controls. The energy contributions of endothelial-, neural-, and myogenic-related frequency bands were also significantly smaller in cancer patients. The present study has revealed significant differences in the beat-to-beat and spectral indexes of skin-surface-acquired LDF signals between control subjects and breast-cancer patients. This illustrates that LDF indexes may be useful for monitoring the changes in the MBF perfusion condition induced by breast cancer. Since the breast-cancer patients were at TNM stages 0- 2, the present findings may aid the development of indexes for detecting breast cancer.

Increase in Multicast OFDM Data Rate in PLC Network using Adaptive LP-OFDM

OpenAIRE

Maiga , Ali; Baudais , Jean-Yves; Hélard , Jean-François

2009-01-01

ISBN: 978-1-4244-3523-4; International audience; Linear precoding (LP) technique applied to OFDM systems has already proved its ability to significantly increase the system throughput in a powerline communication (PLC) context. In this paper, we propose resource allocation algorithms based on the LP technique to increase the multicast OFDM systems bit rate. The conventional multicast capacity is limited by the user which experiences the worst channel conditions. To increase the multicast bit ...

77 FR 71585 - Brookfield Energy Marketing LP v. ISO New England Inc.; Notice of Complaint

Science.gov (United States)

2012-12-03

... Energy Marketing LP v. ISO New England Inc.; Notice of Complaint Take notice that on November 21, 2012...), Brookfield Energy Marketing LP (Complainant) filed a formal complaint against ISO New England Inc... notification when a document is added to a subscribed docket(s). For assistance with any FERC Online service...

76 FR 45247 - Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint

Science.gov (United States)

2011-07-28

... Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint Take notice that on July 20, 2011... Marketing Company (Complainant) filed a formal complaint against SFPP L.P. (SFPP or Respondent) alleging... with any FERC Online service, please e-mail [email protected] , or call (866) 208-3676 (toll...

Sunoco Pipeline, L.P. Clean Water Act Settlement - 2017

Science.gov (United States)

EPA, and the U.S. Department of Justice announced that Sunoco Pipeline, L.P. (Sunoco) has agreed to pay a civil penalty for alleged violation of the Clean Water Act stemming from a 2012 gasoline discharge near Wellington, Ohio.

Modulation of phosducin-like protein 3 (PhLP3 levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner.

Directory of Open Access Journals (Sweden)

Nandini V L Hayes

Full Text Available Phosducin-like protein 3 (PhLP3 forms a ternary complex with the ATP-dependent molecular chaperone CCT and its folding client tubulin. In vitro studies suggest PhLP3 plays an inhibitory role in β-tubulin folding while conversely in vivo genetic studies suggest PhLP3 is required for the correct folding of β-tubulin. We have a particular interest in the cytoskeleton, its chaperones and their role in determining cellular phenotypes associated with high level recombinant protein expression from mammalian cell expression systems.As studies into PhLP3 function have been largely carried out in non mammalian systems, we examined the effect of human PhLP3 over-expression and siRNA silencing using a single murine siRNA on both tubulin and actin systems in mammalian Chinese hamster ovary (CHO cell lines. We show that over-expression of PhLP3 promotes an imbalance of α and β tubulin subunits, microtubule disassembly and cell death. In contrast, β-actin levels are not obviously perturbed. On-the-other-hand, RNA silencing of PhLP3 increases RhoA-dependent actin filament formation and focal adhesion formation and promotes a dramatic elongated fibroblast-like change in morphology. This was accompanied by an increase in phosphorylated MAPK which has been associated with promoting focal adhesion assembly and maturation. Transient overexpression of PhLP3 in knockdown experiments rescues cells from the morphological change observed during PhLP3 silencing but mitosis is perturbed, probably reflecting a tipping back of the balance of PhLP3 levels towards the overexpression state.Our results support the hypothesis that PhLP3 is important for the maintenance of β-tubulin levels in mammalian cells but also that its modulation can promote actin-based cytoskeletal remodelling by a mechanism linked with MAPK phosphorylation and RhoA-dependent changes. PhLP3 levels in mammalian cells are thus finely poised and represents a novel target for engineering industrially

76 FR 45246 - Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint

Science.gov (United States)

2011-07-28

... and Marketing Company v. SFPP, L.P.; Notice of Complaint Take notice that on July 20, 2011, pursuant...), Tesoro Refining and Marketing Company (Tesoro) filed a formal complaint against SFPP, L.P. (SFPP). Tesoro... notification when a document is added to a subscribed docket(s). For assistance with any FERC Online service...

77 FR 28375 - Eagle Rock Desoto Pipeline, L.P.; Notice of Petition for Rate Approval

Science.gov (United States)

2012-05-14

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR12-25-000] Eagle Rock Desoto Pipeline, L.P.; Notice of Petition for Rate Approval Take notice that on May 1, 2012, Eagle Rock Desoto Pipeline, L.P. (Desoto) filed a Rate Election pursuant to 284.123(b)(1) of the Commissions...

Triglyceride glucose index, a marker of insulin resistance, is associated with coronary artery stenosis in asymptomatic subjects with type 2 diabetes.

Science.gov (United States)

Lee, Eun Young; Yang, Hae Kyung; Lee, Joonyub; Kang, Borami; Yang, Yeoree; Lee, Seung-Hwan; Ko, Seung-Hyun; Ahn, Yu-Bae; Cha, Bong Yun; Yoon, Kun-Ho; Cho, Jae Hyoung

2016-09-15

Insulin resistance is one of the most important contributing factors to cardiovascular disease. This study aimed to investigate the association between coronary artery stenosis (CAS) and triglyceride glucose index (TyG index), a simple insulin resistance marker, in asymptomatic subjects with type 2 diabetes. We recruited asymptomatic adults with type 2 diabetes but without previous history of coronary heart disease (n = 888). Significant CAS was defined as maximum intraluminal stenosis ≥70 % by coronary CT angiography. TyG index was calculated as log [fasting triglycerides (mg/dl) x fasting glucose (mg/dl)/2]. Mean age was 63.8 ± 9.5 and 58.9 % of the subjects were men. We analyzed the participants according to the tertile of TyG index. The TyG index was correlated with HOMA-IR (r = 0.397, P index were younger but showed worse clinical and metabolic parameters. The prevalence of CAS was higher in subjects with higher tertile of TyG compared with those with lower tertile of TyG (14 % vs. 7.8 %, P = 0.022). On multiple regression analysis, the highest tertile of TyG index was an independent risk factor for CAS after adjustment for other confounders (odds ratio, 3.19 [95 % CI, 1.371-7.424]). Subgroup analysis showed that TyG index showed more significant association with CAS in patients with risk factors such as old age, longer duration of diabetes, poor glycemic control, no statin use, and male gender. Higher TyG index is associated with increased risk of CAS in asymptomatic subjects with type 2 diabetes, particularly when they have risk factors for cardiovascular disease. This study was retrospectively registered in ClinicalTrials. gov with the registration number of NCT02070926 in Feb 23, 2014.

State of the Art in LP-WAN Solutions for Industrial IoT Services

OpenAIRE

Sanchez-Iborra, Ramon; Cano, Maria-Dolores

2016-01-01

The emergence of low-cost connected devices is enabling a new wave of sensorization services. These services can be highly leveraged in industrial applications. However, the technologies employed so far for managing this kind of system do not fully cover the strict requirements of industrial networks, especially those regarding energy efficiency. In this article a novel paradigm, called Low-Power Wide Area Networking (LP-WAN), is explored. By means of a cellular-type architecture, LP-WAN–base...

78 FR 48205 - Ranger Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application

Science.gov (United States)

2013-08-07

... Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application August 1, 2013. AGENCY... Management, L.P. (``Ranger'') and Ranger Funds Investment Trust (the ``Trust''). Summary of Application... (e) certain registered management investment companies and unit investment trusts outside of the same...

76 FR 66710 - Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing, Soliciting Comments...

Science.gov (United States)

2011-10-27

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 5984-063] Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing, Soliciting Comments, Motions To Intervene, and....: 5984-063. c. Date Filed: May 10, 2011. d. Applicant: Erie Boulevard Hydropower, L.P. (dba Brookfield...

Reliability of levator scapulae index in subjects with and without scapular downward rotation syndrome.

Science.gov (United States)

Lee, Ji-Hyun; Cynn, Heon-Seock; Choi, Woo-Jeong; Jeong, Hyo-Jung; Yoon, Tae-Lim

2016-05-01

The objective of this study was to introduce levator scapulae (LS) measurement using a caliper and the levator scapulae index (LSI) and to investigate intra- and interrater reliability of the LSI in subjects with and without scapular downward rotation syndrome (SDRS). Two raters measured LS length twice in 38 subjects (19 with SDRS and 19 without SDRS). For reliability testing, intraclass correlation coefficients (ICCs), standard error of measurement (SEM), and minimal detectable change (MDC) were calculated. Intrarater reliability analysis resulted with ICCs ranging from 0.94 to 0.98 in subjects with SDRS and 0.96 to 0.98 in subjects without SDRS. These results represented that intrarater reliability in both groups were excellent for measuring LS length with the LSI. Interrater reliability was good (ICC: 0.82) in subjects with SDRS; however, interrater reliability was moderate (ICC: 0.75) in subjects without SDRS. Additionally, SEM and MDC were 0.13% and 0.36% in subjects with SDRS and 0.35% and 0.97% in subjects without SDRS. In subjects with SDRS, low dispersion of the measurement errors and MDC were shown. This study suggested that the LSI is a reliable method to measure LS length and is more reliable for subjects with SDRS. Copyright © 2015 Elsevier Ltd. All rights reserved.

Validation of ozone profile retrievals derived from the OMPS LP version 2.5 algorithm against correlative satellite measurements

Directory of Open Access Journals (Sweden)

N. A. Kramarova

2018-05-01

Full Text Available The Limb Profiler (LP is a part of the Ozone Mapping and Profiler Suite launched on board of the Suomi NPP satellite in October 2011. The LP measures solar radiation scattered from the atmospheric limb in ultraviolet and visible spectral ranges between the surface and 80 km. These measurements of scattered solar radiances allow for the retrieval of ozone profiles from cloud tops up to 55 km. The LP started operational observations in April 2012. In this study we evaluate more than 5.5 years of ozone profile measurements from the OMPS LP processed with the new NASA GSFC version 2.5 retrieval algorithm. We provide a brief description of the key changes that had been implemented in this new algorithm, including a pointing correction, new cloud height detection, explicit aerosol correction and a reduction of the number of wavelengths used in the retrievals. The OMPS LP ozone retrievals have been compared with independent satellite profile measurements obtained from the Aura Microwave Limb Sounder (MLS, Atmospheric Chemistry Experiment Fourier Transform Spectrometer (ACE-FTS and Odin Optical Spectrograph and InfraRed Imaging System (OSIRIS. We document observed biases and seasonal differences and evaluate the stability of the version 2.5 ozone record over 5.5 years. Our analysis indicates that the mean differences between LP and correlative measurements are well within required ±10 % between 18 and 42 km. In the upper stratosphere and lower mesosphere (> 43 km LP tends to have a negative bias. We find larger biases in the lower stratosphere and upper troposphere, but LP ozone retrievals have significantly improved in version 2.5 compared to version 2 due to the implemented aerosol correction. In the northern high latitudes we observe larger biases between 20 and 32 km due to the remaining thermal sensitivity issue. Our analysis shows that LP ozone retrievals agree well with the correlative satellite observations in characterizing

Serum Lp-PLA2: as a novel viewpoint in periodontal treatment of hyperlipidaemics.

Science.gov (United States)

Fentoğlu, Özlem; Kirzioğlu, Fatma Yeşim; Tözüm Bulut, Memduha; Kurgan, Şivge; Koçak, Havva; Sütcü, Recep; Kale Köroğlu, Banu; Günhan, Meral

2015-01-01

To evaluate the effects of periodontal treatment on serum lipoprotein-associated phospholipase A2 (Lp-PLA2) and C-reactive protein (CRP) levels in hyperlipidaemic patients with periodontitis. The study included 52 hyperlipidaemics and 28 systemically healthy controls (C) with periodontitis. Of the 52 hyperlipidaemics, 29 received a suggested diet (HD), and 23 of them were prescribed statin (HS). Clinical periodontal parameters, serum lipids, Lp-PLA2, and CRP levels were assessed at the baseline and 2 months after the completion of the nonsurgical periodontal treatment (2MPT). Serum parameters were also evaluated 1 week following the periodontal treatment (1WPT). At the baseline, patients in the HS group had a higher percentage of bleeding on probing than those in the C and HD groups. Hyperlipidaemics had higher serum triglyceride levels than the control group at 2MPT compared to the baseline. At 2MPT, the levels of Lp-PLA2 in the HS group were significantly higher compared to the baseline and 1WPT. There were no statistically significant differences in CRP levels between study periods for all groups. The periodontal treatment may affect the inflammatory control of hyperlipidaemic patients with periodontitis via increased Lp-PLA2 levels and severity of the impaired lipid metabolism. These findings may be important regarding the therapeutic strategies for hyperlipidaemics with periodontitis.

76 FR 81360 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Operation Without Normal...

Science.gov (United States)

2011-12-28

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. FAA-2011-1172: Special Conditions No. 25-453-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280... Aerospace LP (GALP) Model G280 airplane. This airplane will have a novel or unusual design feature...

Lp-PLA2 activity is associated with increased risk of diabetic retinopathy: a longitudinal disease progression study.

Science.gov (United States)

Siddiqui, Moneeza K; Kennedy, Gwen; Carr, Fiona; Doney, Alexander S F; Pearson, Ewan R; Morris, Andrew D; Johnson, Toby; McLaughlin, Megan M; Williams, Rachel E; Palmer, Colin N A

2018-06-01

The aim of the study was to examine the association between lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) activity levels and incident diabetic retinopathy and change in retinopathy grade. This was a cohort study of diabetic participants with serum collected at baseline and routinely collected diabetic retinal screening data. Participants with type 2 diabetes from the GoDARTS (Genetics of Diabetes Audit and Research in Tayside Scotland) cohort were used. This cohort is composed of individuals of white Scottish ancestry from the Tayside region of Scotland. Survival analysis accounting for informative censoring by modelling death as a competing risk was performed for the development of incident diabetic retinopathy from a disease-free state in a 3 year follow-up period (n = 1364) by stratified Lp-PLA 2 activity levels (in quartiles). The same analysis was performed for transitions to more severe grades. The hazard of developing incident diabetic retinopathy was 2.08 times higher (95% CI 1.64, 2.63) for the highest quartile of Lp-PLA 2 activity compared with the lowest. Higher Lp-PLA 2 activity levels were associated with a significantly increased risk for transitions to all grades. The hazards of developing observable (or more severe) and referable (or more severe) retinopathy were 2.82 (95% CI 1.71, 4.65) and 1.87 (95% CI 1.26, 2.77) times higher for the highest quartile of Lp-PLA 2 activity compared with the lowest, respectively. Higher Lp-PLA 2 levels are associated with increased risk of death and the development of incident diabetic retinopathy, as well as transitions to more severe grades of diabetic retinopathy. These associations are independent of calculated LDL-cholesterol and other traditional risk factors. Further, this biomarker study shows that the association is temporally sensitive to the proximity of the event to measurement of Lp-PLA 2.

76 FR 25229 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane, Dynamic Test Requirements...

Science.gov (United States)

2011-05-04

... Memorandum ``Side-Facing Seats on Transport Category Airplanes'' and draft Issue Paper ``Dynamic Test...; Special Conditions No. 25-425-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane... are issued for the Gulfstream Aerospace LP (GALP) model G250 airplane. This airplane will have a novel...

77 FR 71680 - Buckeye East Chicago Railroad, LLC-Acquisition and Operation Exemption-Buckeye Partners, L.P.

Science.gov (United States)

2012-12-03

... Chicago Railroad, LLC--Acquisition and Operation Exemption--Buckeye Partners, L.P. Buckeye East Chicago... acquire from Buckeye Partners, L.P., a noncarrier, and to operate approximately 7,065 feet (1.34 miles) of..., 2012. By the Board, Rachel D. Campbell, Director, Office of Proceedings. Jeffrey Herzig, Clearance Unit...

76 FR 66660 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Operation Without Normal...

Science.gov (United States)

2011-10-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. FAA-2011-1172: Notice No. 25-11-17-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane... Aerospace LP (GALP) Model G280 airplane. This airplane will have a novel or unusual design feature...

Antitumor activity of chLpMab-2, a human-mouse chimeric cancer-specific antihuman podoplanin antibody, via antibody-dependent cellular cytotoxicity.

Science.gov (United States)

Kaneko, Mika K; Yamada, Shinji; Nakamura, Takuro; Abe, Shinji; Nishioka, Yasuhiko; Kunita, Akiko; Fukayama, Masashi; Fujii, Yuki; Ogasawara, Satoshi; Kato, Yukinari

2017-04-01

Human podoplanin (hPDPN), a platelet aggregation-inducing transmembrane glycoprotein, is expressed in different types of tumors, and it binds to C-type lectin-like receptor 2 (CLEC-2). The overexpression of hPDPN is involved in invasion and metastasis. Anti-hPDPN monoclonal antibodies (mAbs) such as NZ-1 have shown antitumor and antimetastatic activities by binding to the platelet aggregation-stimulating (PLAG) domain of hPDPN. Recently, we developed a novel mouse anti-hPDPN mAb, LpMab-2, using the cancer-specific mAb (CasMab) technology. In this study we developed chLpMab-2, a human-mouse chimeric anti-hPDPN antibody, derived from LpMab-2. chLpMab-2 was produced using fucosyltransferase 8-knockout (KO) Chinese hamster ovary (CHO)-S cell lines. By flow cytometry, chLpMab-2 reacted with hPDPN-expressing cancer cell lines including glioblastomas, mesotheliomas, and lung cancers. However, it showed low reaction with normal cell lines such as lymphatic endothelial and renal epithelial cells. Moreover, chLpMab-2 exhibited high antibody-dependent cellular cytotoxicity (ADCC) against PDPN-expressing cells, despite its low complement-dependent cytotoxicity. Furthermore, treatment with chLpMab-2 abolished tumor growth in xenograft models of CHO/hPDPN, indicating that chLpMab-2 suppressed tumor development via ADCC. In conclusion, chLpMab-2 could be useful as a novel antibody-based therapy against hPDPN-expressing tumors. © 2017 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

The Rorschach Egocentricity Index in subjects with intellectual disability: a study on the incidence of different psychological pathologies.

Science.gov (United States)

Colucci, G; Pellicciotta, A; Buono, S; Di Nuovo, S F

1998-10-01

The aims of the present research were to assess the level of self-concern in people with intellectual disability using the Rorschach Egocentricity Index, to correlate the Index with other Rorschach and IQ variables, and to study the effect of associated psychological pathology. The Rorschach Inkblot Test and the Wechsler Intelligence Scale were administered to a group of 75 subjects with intellectual disability, aged between 18 and 38 years, who were divided into subgroups according to their additional diagnosis (i.e. personality disorders, psychosis and depression). A fourth subgroup was composed of people with intellectual disability but without other pathologies. The Egocentricity Index was very low in the subjects with intellectual disability and differences were a result of the effects of additional psychological pathologies. The meaning of the measurement of egocentricity in people with intellectual disability is discussed.

Learning to perceive and recognize a second language: the L2LP model revised.

Science.gov (United States)

van Leussen, Jan-Willem; Escudero, Paola

2015-01-01

We present a test of a revised version of the Second Language Linguistic Perception (L2LP) model, a computational model of the acquisition of second language (L2) speech perception and recognition. The model draws on phonetic, phonological, and psycholinguistic constructs to explain a number of L2 learning scenarios. However, a recent computational implementation failed to validate a theoretical proposal for a learning scenario where the L2 has less phonemic categories than the native language (L1) along a given acoustic continuum. According to the L2LP, learners faced with this learning scenario must not only shift their old L1 phoneme boundaries but also reduce the number of categories employed in perception. Our proposed revision to L2LP successfully accounts for this updating in the number of perceptual categories as a process driven by the meaning of lexical items, rather than by the learners' awareness of the number and type of phonemes that are relevant in their new language, as the previous version of L2LP assumed. Results of our simulations show that meaning-driven learning correctly predicts the developmental path of L2 phoneme perception seen in empirical studies. Additionally, and to contribute to a long-standing debate in psycholinguistics, we test two versions of the model, with the stages of phonemic perception and lexical recognition being either sequential or interactive. Both versions succeed in learning to recognize minimal pairs in the new L2, but make diverging predictions on learners' resulting phonological representations. In sum, the proposed revision to the L2LP model contributes to our understanding of L2 acquisition, with implications for speech processing in general.

77 FR 77122 - Pyxis Capital, L.P., et al.;

Science.gov (United States)

2012-12-31

... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30316; 812-13489-01] Pyxis Capital, L.P., et al.; Notice of Application December 21, 2012. AGENCY: Securities and Exchange Commission (the ``Commission''). ACTION: Notice of an application for an order under section 6(c) of the...

Association between subjective actual sleep duration, subjective sleep need, age, body mass index, and gender in a large sample of young adults.

Science.gov (United States)

Kalak, Nadeem; Brand, Serge; Beck, Johannes; Holsboer-Trachsler, Edith; Wollmer, M Axel

2015-01-01

Poor sleep is a major health concern, and there is evidence that young adults are at increased risk of suffering from poor sleep. There is also evidence that sleep duration can vary as a function of gender and body mass index (BMI). We sought to replicate these findings in a large sample of young adults, and also tested the hypothesis that a smaller gap between subjective sleep duration and subjective sleep need is associated with a greater feeling of being restored. A total of 2,929 university students (mean age 23.24±3.13 years, 69.1% female) took part in an Internet-based survey. They answered questions related to demographics and subjective sleep patterns. We found no gender differences in subjective sleep duration, subjective sleep need, BMI, age, or feeling of being restored. Nonlinear associations were observed between subjective sleep duration, BMI, and feeling of being restored. Moreover, a larger discrepancy between subjective actual sleep duration and subjective sleep need was associated with a lower feeling of being restored. The present pattern of results from a large sample of young adults suggests that males and females do not differ with respect to subjective sleep duration, BMI, or feeling of being restored. Moreover, nonlinear correlations seemed to provide a more accurate reflection of the relationship between subjective sleep and demographic variables.

Continuous and Lp estimates for the complex Monge-Ampère equation on bounded domains in ℂn

Directory of Open Access Journals (Sweden)

Patrick W. Darko

2002-01-01

Full Text Available Continuous solutions with continuous data and Lp solutions with Lp data are obtained for the complex Monge-Ampère equation on bounded domains, without requiring any smoothness of the domains.

The glycaemic index values of foods containing fructose are affected by metabolic differences between subjects.

Science.gov (United States)

Wolever, T M S; Jenkins, A L; Vuksan, V; Campbell, J

2009-09-01

Glycaemic responses are influenced by carbohydrate absorption rate, type of monosaccharide absorbed and the presence of fat; the effect of some of these factors may be modulated by metabolic differences between subjects. We hypothesized that glycaemic index (GI) values are affected by the metabolic differences between subjects for foods containing fructose or fat, but not for starchy foods. The GI values of white bread (WB), fruit leather (FL) and chocolate-chip cookies (CCC) (representing starch, fructose and fat, respectively) were determined in subjects (n=77) recruited to represent all 16 possible combinations of age (40 years), sex (male, female), ethnicity (Caucasian, non-Caucasian) and body mass index (BMI) (25 kg/m2) using glucose as the reference. At screening, fasting insulin, lipids, c-reactive protein (CRP), aspartate transaminase (AST) and waist circumference (WC) were measured. There were no significant main effects of age, sex, BMI or ethnicity on GI, but there were several food x subject-factor interactions. Different factors affected each food's area under the curve (AUC) and GI. The AUC after oral glucose was related to ethnicity, age and triglycerides (r 2=0.27); after WB to ethnicity, age, triglycerides, sex and CRP (r 2=0.43); after CCC to age and weight (r 2=0.18); and after FL to age and CRP (r 2=0.12). GI of WB was related to ethnicity (r 2=0.12) and of FL to AST, insulin and WC (r 2=0.23); but there were no significant correlations for CCC. The GI values of foods containing fructose might be influenced by metabolic differences between -subjects, whereas the GI of starchy foods might be affected by ethnicity. However, the proportion of variation explained by subject factors is small.

78 FR 28273 - Alpine Investors IV SBIC, LP; Notice Seeking Exemption Under Section 312 of the Small Business...

Science.gov (United States)

2013-05-14

... SMALL BUSINESS ADMINISTRATION [License No. 09/09-0461] Alpine Investors IV SBIC, LP; Notice... hereby given that Alpine Investors IV SBIC, LP, 3 Embarcadero Center, Suite 2330, San Francisco, CA, a...'') Rules and [[Page 28274

78 FR 68044 - Erie Boulevard Hydropower, L.P.; Notice of Scoping Meetings and Environmental Site Review and...

Science.gov (United States)

2013-11-13

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 7320-042] Erie Boulevard Hydropower, L.P.; Notice of Scoping Meetings and Environmental Site Review and Soliciting Scoping Comments.... Date filed: July 1, 2013. d. Applicant: Erie Boulevard Hydropower, L.P. e. Name of Project: Chasm...

The importance of age and statin therapy in the interpretation of Lp-PLA(2) in ACS patients, and relation to CRP.

Science.gov (United States)

Franeková, J; Kettner, J; Kubíček, Z; Jabor, A

2015-01-01

C-reactive protein (CRP) is a marker of arterial inflammation while lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is related to plaque instability. The aim of this study was to evaluate the correlation between the risk of unstable plaque presenting as acute coronary syndrome (ACS) and Lp-PLA(2), and to assess the influence of statins on interpretation of Lp-PLA(2). A total of 362 consecutive patients presenting to the emergency department (ED) with acute chest pain suggestive of ACS were evaluated by cardiologists as STEMI, NSTEMI, or unstable angina, and non-ACS. Serum biomarkers measured on admission: troponin I, C-reactive protein (Abbott), and Lp-PLA(2) (DiaDexus). Four groups were defined according to the final diagnosis and history of statin medication: ACS/statin-; ACS/statin+; non-ACS/statin-; non-ACS/statin+. Lp-PLA(2) was highest in ACS/statin- group; statins decreased Lp-PLA(2) both in ACS and non-ACS of about 20 %. Lp-PLA(2) was higher in ACS patients in comparison with non-ACS patients group without respect to statin therapy (pPLA(2) predicted worse outcome (in terms of acute coronary syndrome) effectively in patients up to 62 years; limited prediction was found in older patients. C-reactive protein (CRP) failed to discriminate four groups of patients. Statin therapy and age should be taken into consideration while interpreting Lp-PLA(2) concentrations and lower cut-off values should be used for statin-treated persons.

LP 400-22, A Very Low Mass and High-Velocity White Dwarf

Science.gov (United States)

Kawka, Adela; Vennes, Stephane; Oswalt, Terry D.; Smith, J. Allyn; Silvestri, Nicole M.

2006-01-01

We report the identification of LP 400-22 (WD 2234+222) as a very low mass and high-velocity white dwarf. The ultraviolet GALEX and optical photometric colors and a spectral line analysis of LP 400-22 show this star to have an effective temperature of 11,080+/-140 K and a surface gravity of log g = 6.32 +/-0.08. Therefore, this is a helium-core white dwarf with a mass of 0.17 M,. The tangential velocity of this white dwarf is 414+/-43 km/s, making it one of the fastest moving white dwarfs known. We discuss probable evolutionary scenarios for this remarkable object.

77 FR 20871 - Praesidian Capital Opportunity Fund III, LP; License No. 02/02-0647; Notice Seeking Exemption...

Science.gov (United States)

2012-04-06

... contemplated to fund working capital and capital expenditures. The financing is brought within the purview of... SMALL BUSINESS ADMINISTRATION Praesidian Capital Opportunity Fund III, LP; License No. 02/02- 0647... given that Praesidian Capital Opportunity Fund III, LP, 419 Park Avenue South, New York, NY 10016, a...

75 FR 6414 - Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

Science.gov (United States)

2010-02-09

... SMALL BUSINESS ADMINISTRATION [License No. 05/75-0257] Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Cardinal Growth, L.P., 311 South Wacker Driver, Suite 5500, Chicago, IL 60606, a Federal...

78 FR 77770 - Ironwood Equity Fund, LP; Notice Seeking Exemption Under Section 312 of the Small Business...

Science.gov (United States)

2013-12-24

... proposes to Finance a small business in which its Associate Ironwood Mezzanine Fund II, LP has an equity... SMALL BUSINESS ADMINISTRATION [ License No. 01171-0406] Ironwood Equity Fund, LP; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby...

78 FR 62348 - Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing and Soliciting Motions...

Science.gov (United States)

2013-10-18

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 7320-042] Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing and Soliciting Motions To Intervene and Protests.... Date filed: July 1, 2013. d. Applicant: Erie Boulevard Hydropower, L.P. e. Name of Project: Chasm...

Geometric phase due to orbit-orbit interaction: rotating LP11 modes in a two-mode fiber

Science.gov (United States)

Pradeep Chakravarthy, T.; Naik, Dinesh N.; Viswanathan, Nirmal K.

2017-10-01

Accumulation of geometric phase due to non-coplanar propagation of higher-order modes in an optical fiber is experimentally demonstrated. Vertically-polarized LP11 fiber mode, excited in a horizontally-held, torsion-free, step-index, two-mode optical fiber, rotates due to asymmetry in the propagating k-vectors, arising due to off-centered beam location at the fiber input. Perceiving the process as due to rotation of the fiber about the off-axis launch position, the orbital Berry phase accumulation upon scanning the launch position in a closed-loop around the fiber axis manifests as rotational Doppler effect, a consequence of orbit-orbit interaction. The anticipated phase accumulation as a function of the input launch position, observed through interferometry is connected to the mode rotation angle, quantified using the autocorrelation method.

Sparse filtering with the generalized lp/lq norm and its applications to the condition monitoring of rotating machinery

Science.gov (United States)

Jia, Xiaodong; Zhao, Ming; Di, Yuan; Li, Pin; Lee, Jay

2018-03-01

Sparsity is becoming a more and more important topic in the area of machine learning and signal processing recently. One big family of sparse measures in current literature is the generalized lp /lq norm, which is scale invariant and is widely regarded as normalized lp norm. However, the characteristics of the generalized lp /lq norm are still less discussed and its application to the condition monitoring of rotating devices has been still unexplored. In this study, we firstly discuss the characteristics of the generalized lp /lq norm for sparse optimization and then propose a method of sparse filtering with the generalized lp /lq norm for the purpose of impulsive signature enhancement. Further driven by the trend of industrial big data and the need of reducing maintenance cost for industrial equipment, the proposed sparse filter is customized for vibration signal processing and also implemented on bearing and gearbox for the purpose of condition monitoring. Based on the results from the industrial implementations in this paper, the proposed method has been found to be a promising tool for impulsive feature enhancement, and the superiority of the proposed method over previous methods is also demonstrated.

Variation in LPA is associated with Lp(a levels in three populations from the Third National Health and Nutrition Examination Survey.

Directory of Open Access Journals (Sweden)

Logan Dumitrescu

2011-01-01

Full Text Available The distribution of lipoprotein(a [Lp(a] levels can differ dramatically across diverse racial/ethnic populations. The extent to which genetic variation in LPA can explain these differences is not fully understood. To explore this, 19 LPA tagSNPs were genotyped in 7,159 participants from the Third National Health and Nutrition Examination Survey (NHANES III. NHANES III is a diverse population-based survey with DNA samples linked to hundreds of quantitative traits, including serum Lp(a. Tests of association between LPA variants and transformed Lp(a levels were performed across the three different NHANES subpopulations (non-Hispanic whites, non-Hispanic blacks, and Mexican Americans. At a significance threshold of p<0.0001, 15 of the 19 SNPs tested were strongly associated with Lp(a levels in at least one subpopulation, six in at least two subpopulations, and none in all three subpopulations. In non-Hispanic whites, three variants were associated with Lp(a levels, including previously known rs6919246 (p = 1.18 × 10(-30. Additionally, 12 and 6 variants had significant associations in non-Hispanic blacks and Mexican Americans, respectively. The additive effects of these associated alleles explained up to 11% of the variance observed for Lp(a levels in the different racial/ethnic populations. The findings reported here replicate previous candidate gene and genome-wide association studies for Lp(a levels in European-descent populations and extend these findings to other populations. While we demonstrate that LPA is an important contributor to Lp(a levels regardless of race/ethnicity, the lack of generalization of associations across all subpopulations suggests that specific LPA variants may be contributing to the observed Lp(a between-population variance.

The effect of an inhibitor of gut serotonin (LP533401) during the induction of periodontal disease.

Science.gov (United States)

Lima, G M G; Corazza, B J M; Moraes, R M; de Oliveira, F E; de Oliveira, L D; Franco, G C N; Perrien, D S; Elefteriou, F; Anbinder, A L

2016-10-01

LP533401 is an inhibitor of tryptophan hydroxylase 1, which regulates serotonin production in the gut. Previous work indicates that LP533401 has an anabolic effect in bone. Thus, we hypothesized that inhibition of gut serotonin production may modulate the host response in periodontal disease. In this study, we aimed to analyze the effects of LP533401 in a rat periodontitis model to evaluate the role of gut serotonin in periodontitis pathophysiology. Twenty-four rats were divided into three groups: treated group (T: ligature-induced periodontal disease and LP533401, 25 mg/kg/d) by gavage; ligature group (L: ligature-induced periodontal disease only); and control group (C: without ligature-induced periodontal disease). After 28 d, radiographic alveolar bone support was measured on digital radiographs, and alveolar bone volume fraction, tissue mineral density and trabeculae characteristics were quantified by microcomputed tomography in the right hemi-mandible. Left hemi-mandibles were decalcified and alveolar bone loss, attachment loss and area of collagen in the gingiva were histologically analyzed. Significant difference between the L and C groups was found, confirming that periodontal disease was induced. We observed no difference between the T and L groups regarding alveolar bone destruction and area of collagen. LP533401 (25 mg/kg/d) for 28 d does not prevent bone loss and does not modulate host response in a rat model of induced periodontal disease. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

78 FR 48177 - Purdue Pharma L.P.; Withdrawal of Approval of a New Drug Application for Oxycontin

Science.gov (United States)

2013-08-07

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0883] Purdue Pharma L.P.; Withdrawal of Approval of a New Drug Application for Oxycontin AGENCY: Food and Drug... Purdue Pharma L.P. (Purdue), One Stamford Forum, Stamford, CT 06901-3431. Purdue has voluntarily...

77 FR 11618 - Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

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2012-02-27

... SMALL BUSINESS ADMINISTRATION [License No. 03/03-0247] Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Solutions Capital I, L.P., 1100 Wilson Blvd., Suite 3000, Arlington, VA 22209, a Federal Licensee under the...

76 FR 18210 - Texas Eastern Transmission, LP; Notice of Application

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2011-04-01

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-138-000] Texas Eastern Transmission, LP; Notice of Application On March 15, 2011, Texas Eastern Transmission Corporation (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056-5310, filed with the Federal Energy Regulatory...

Prenatal exposure to a maternal LP diet decreases BDNF expression in the brains of the neonatal offspring

Science.gov (United States)

Maternal low protein (LP) diets during gestation cause learning and mernmy impai1ment as well as cognitive deficits in the neonatal and adult offsp1ing. The cellular and molecular mechanism that mediate the deleterious effects of prenatal exposure to a maternal LP diet on cognitive function is egreg...

78 FR 338 - Buckeye Hammond Railroad, L.L.C.; Acquisition and Operation Exemption; Buckeye Partners, L.P.

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2013-01-03

... Railroad, L.L.C.; Acquisition and Operation Exemption; Buckeye Partners, L.P. Buckeye Hammond Railroad, L.L... acquire from Buckeye Partners, L.P., a noncarrier, and to operate approximately 6,797 feet (1.29 miles) of...: December 26, 2012. By the Board, Rachel D. Campbell, Director, Office of Proceedings. Jeffrey Herzig...

78 FR 4842 - Linden VFT, LLC v. Brookfield Energy Marketing, LP, Cargill Power Markets, LLC; Notice of Complaint

Science.gov (United States)

2013-01-23

... v. Brookfield Energy Marketing, LP, Cargill Power Markets, LLC; Notice of Complaint Take notice that... Brookfield Energy Marketing, LP and Cargill Power Markets, LLC (Respondents) alleging that, Respondents... subscribed docket(s). For assistance with any FERC Online service, please email [email protected

RANS simulation of the thermal mixing in HTTF LP during normal operation conditions – High Temperature Test Facility at Oregon State University

International Nuclear Information System (INIS)

Gradecka, Malwina J.; Woods, Brian

2014-01-01

Since High Temperature Gas-cooled Reactors are being considered as the most promising design of upcoming IV Gen reactors, key research areas were identified to address safety aspects of this design. A number of simulations and experiments need to be conducted in this field. In this paper, thermal-hydraulics aspects of coolant flow through Lower Plenum (LP) of HTGR were considered, specifically flow characteristics to identify the risk of temperature stratification in LP and hot spotting on LP floor. Local temperature gradients can cause material degradation. As the power profile is non-uniform across the core, jets of coolant exit the core region at different temperatures and enter the LP impinging on LP floor causing hot spots at LP structure and temperature stratification. To address those issues numerical simulation and an experiment are being developed. The numerical simulation provides coolant flow velocity and temperature fields. The purpose of this study is to investigate the mixing phenomenon in the LP due to risk of the hot streaking and thermal stratification phenomena during normal operation of HTTF. The following aspect are being examined: identification of gas flow behavior in lower plenum of HTTF based on CFD simulations, identification of hot streaking issue in the HTTF lower plenum using CFD tools, and computational investigation of gas mixing efficiency. This paper includes a description of experimental setup of HTTF, guidance for LP CFD modeling, and the results and analysis of CFD simulation. (author)

Subjective and psychophysiological indexes of listening effort in a competing-talker task.

Science.gov (United States)

Mackersie, Carol L; Cones, Heather

2011-02-01

The effects of noise and other competing backgrounds on speech recognition performance are well documented. There is less information, however, on listening effort and stress experienced by listeners during a speech-recognition task that requires inhibition of competing sounds. The purpose was (a) to determine if psychophysiological indexes of listening effort were more sensitive than performance measures (percentage correct) obtained near ceiling level during a competing speech task, (b) to determine the relative sensitivity of four psychophysiological measures to changes in task demand, and (c) to determine the relationships between changes in psychophysiological measures and changes in subjective ratings of stress and workload. A repeated-measures experimental design was used to examine changes in performance, psychophysiological measures, and subjective ratings in response to increasing task demand. Fifteen adults with normal hearing participated in the study. The mean age of the participants was 27 (range: 24-54). Psychophysiological recordings of heart rate, skin conductance, skin temperature, and electromyographic (EMG) activity were obtained during listening tasks of varying demand. Materials from the Dichotic Digits Test were used to modulate task demand. The three levels of task demand were single digits presented to one ear (low-demand reference condition), single digits presented simultaneously to both ears (medium demand), and a series of two digits presented simultaneously to both ears (high demand). Participants were asked to repeat all the digits they heard, while psychophysiological activity was recorded simultaneously. Subjective ratings of task load were obtained after each condition using the National Aeronautics and Space Administration Task Load Index questionnaire. Repeated-measures analyses of variance were completed for each measure using task demand and session as factors. Mean performance was higher than 96% for all listening tasks. There

Norra LP-mudel ajab Eestis juuri / intervjueerinud Sirje Pärismaa

Index Scriptorium Estoniae

2016-01-01

Teaduspõhise LP-mudeli (Learning environment and pedagogical analysis) - abivahendi koolikultuuri parandamiseks ja süsteemsemaks lähenemiseks tekkinud probleemidele - on kasutusele võtnud 10 kooli ja 3 lasteaeda. Norra hariduseksperdid Janne Stoen ja Hanna Jahnsen vastasid Õpetajate Lehe küsimustele

78 FR 64933 - Texas Eastern Transmission, LP; Notice of Application

Science.gov (United States)

2013-10-30

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP14-4-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on October 10, 2013, Texas Eastern Transmission, (Texas Eastern), having its principal place of business at 5400 Westheimer Court, Houston, Texas, 77056...

75 FR 79065 - Emergence Capital Partners SBIC, L.P. License No. 09/79-0454; Notice Seeking Exemption Under...

Science.gov (United States)

2010-12-17

... 95113. The financing is contemplated for working capital and general operating purposes. The financing... SMALL BUSINESS ADMINISTRATION Emergence Capital Partners SBIC, L.P. License No. 09/79-0454; Notice... hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo, CA 94402...

75 FR 39588 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

Science.gov (United States)

2010-07-09

..., San Jose, California 95113. The financing is contemplated for working capital and general operating... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P... Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

76 FR 76474 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

Science.gov (United States)

2011-12-07

..., Emeryville, CA 94608 (``Lithium''). The financing is contemplated for working capital and general operating... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P... Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

76 FR 1491 - Emergence Capital Partners SBIC, L.P. License No. 09/79-0454; Notice Seeking Exemption Under...

Science.gov (United States)

2011-01-10

... financing is contemplated for working capital and general operating purposes. The financing is brought... SMALL BUSINESS ADMINISTRATION Emergence Capital Partners SBIC, L.P. License No. 09/79-0454; Notice... hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo, CA 94402...

76 FR 28843 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

Science.gov (United States)

2011-05-18

... 94404. The financing is contemplated for working capital and general operating purposes. The financing... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P... Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

75 FR 32230 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

Science.gov (United States)

2010-06-07

... is contemplated for working capital and general operating purposes. The financing is brought within... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P... Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

Relationship of body mass index, ankle dorsiflexion, and foot pronation on plantar fascia thickness in healthy, asymptomatic subjects.

Science.gov (United States)

Pascual Huerta, Javier; García, Juan Maria Alarcón; Matamoros, Eva Cosin; Matamoros, Julia Cosin; Martínez, Teresa Díaz

2008-01-01

We sought to investigate the thickness of plantar fascia, measured by means of ultrasonographic evaluation in healthy, asymptomatic subjects, and its relationship to body mass index, ankle joint dorsiflexion range of motion, and foot pronation in static stance. One hundred two feet of 51 healthy volunteers were examined. Sonographic evaluation with a 10-MHz linear array transducer was performed 1 and 2 cm distal to its insertion. Physical examination was also performed to assess body mass index, ankle joint dorsiflexion, and degree of foot pronation in static stance. Both examinations were performed in a blinded manner. Body mass index showed moderate correlation with plantar fascia thickness at the 1- and 2-cm locations. Ankle dorsiflexion range of motion showed no correlation at either location. Foot pronation showed an inverse correlation with plantar fascia thickness at the 2-cm location and no correlation at the 1-cm location. Body mass index and foot supination at the subtalar joint are related to increased thickness at the plantar fascia in healthy, asymptomatic subjects. Although the changes in thickness were small compared with those in patients with symptomatic plantar fasciitis, they could play a role in the mechanical properties of plantar fascia and in the development of plantar fasciitis.

75 FR 32230 - Solutions Capital I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

Science.gov (United States)

2010-06-07

... working capital and general corporate purposes. The financing is brought within the purview of Sec. 107... SMALL BUSINESS ADMINISTRATION [License No. 03/03-0247] Solutions Capital I, L.P.; Notice Seeking... given that Solutions Capital I, L.P., 1100 Wilson Blvd., Suite 3000, Arlington, VA 22209, a Federal...

78 FR 78350 - Houston Pipe Line Company, LP; Notice of Intent to Prepare an Environmental Assessment for the...

Science.gov (United States)

2013-12-26

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP14-13-000] Houston Pipe Line Company, LP; Notice of Intent to Prepare an Environmental Assessment for the Proposed 24-Inch... Hidalgo County, Texas by Houston Pipe Line Company, LP (HPL). The Commission will use this EA in its...

75 FR 3502 - KLH Capital, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act...

Science.gov (United States)

2010-01-21

... SMALL BUSINESS ADMINISTRATION [License No. 04/04-0296] KLH Capital, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that KLH Capital, L.P., 101 East Kennedy Boulevard, Suite 3925, Tampa, Florida 33602, a Federal Licensee under the...

The obesity and fatty liver are reduced by plant-derived Pediococcus pentosaceus LP28 in high fat diet-induced obese mice.

Directory of Open Access Journals (Sweden)

Xingrong Zhao

Full Text Available We evaluated the effect of an oral administration of a plant-derived lactic acid bacterium, Pediococcus pentosaceus LP28 (LP28, on metabolic syndrome by using high fat diet-induced obese mice. The obese mice were divided into 2 groups and fed either a high fat or regular diet for 8 weeks. Each group was further divided into 3 groups, which took LP28, another plant-derived Lactobacillus plantarum SN13T (SN13T or no lactic acid bacteria (LAB. The lean control mice were fed a regular diet without inducing obesity prior to the experiment. LP28 reduced body weight gain and liver lipid contents (triglyceride and cholesterol, in mice fed a high fat diet for 8 weeks (40%, 54%, and 70% less than those of the control group without LAB, and P = 0.018, P<0.001, and P = 0.021, respectively, whereas SN13T and the heat treated LP28 at 121°C for 15 min were ineffective. Abdominal visceral fat in the high fat diet mice fed with LP28 was also lower than that without LAB by 44%, although it was not significant but borderline (P = 0.076. The sizes of the adipocytes and the lipid droplets in the livers were obviously decreased. A real-time PCR analyses showed that lipid metabolism-related genes, such as CD36 (P = 0.013, SCD1 encoding stearoyl-CoA desaturase 1 (not significant but borderline, P = 0.066, and PPARγ encoding peroxisome proliferator-activated receptor gamma (P = 0.039, were down-regulated by taking LP28 continuously, when compared with those of the control group. In conclusion, LP28 may be a useful LAB strain for the prevention and reduction of the metabolic syndrome.

IS30-related transposon mediated insertional inactivation of bile salt hydrolase (bsh1) gene of Lactobacillus plantarum strain Lp20.

Science.gov (United States)

Kumar, Rajesh; Grover, Sunita; Kaushik, Jai K; Batish, Virender Kumar

2014-01-01

Lactobacillus plantarum is a flexible and versatile microorganism that inhabits a variety of niches, and its genome may express up to four bsh genes to maximize its survival in the mammalian gut. However, the ecological significance of multiple bsh genes in L. plantarum is still not clearly understood. Hence, this study demonstrated the disruption of bile salt hydrolase (bsh1) gene due to the insertion of a transposable element in L. plantarum Lp20 - a wild strain of human fecal origin. Surprisingly, L. plantarum strain Lp20 produced a ∼2.0 kb bsh1 amplicon against the normal size (∼1.0 kb) bsh1 amplicon of Bsh(+)L. plantarum Lp21. Strain Lp20 exhibited minimal Bsh activity in spite of having intact bsh2, bsh3 and bsh4 genes in its genome and hence had a Bsh(-) phenotype. Cloning and sequence characterization of Lp20 bsh1 gene predicted four individual open reading frames (ORFs) within this region. BLAST analysis of ORF1 and ORF2 revealed significant sequence similarity to the L. plantarum bsh1 gene while ORF3 and ORF4 showed high sequence homology to IS30-family transposases. Since, IS30-related transposon element was inserted within Lp20 bsh1 gene in reverse orientation (3'-5'), it introduced several stop codons and disrupted the protein reading frames of both Bsh1 and transposase. Inverted terminal repeats (GGCAGATTG) of transposon, mediated its insertion at 255-263 nt and 1301-1309 nt positions of Lp20 bsh1 gene. In conclusion, insertion of IS30 related-transposon within the bsh1 gene sequence of L. plantarum strain Lp20 demolished the integrity and functionality of Bsh1 enzyme. Additionally, this transposon DNA sequence remains active among various Lactobacillus spp. and hence harbors the potential to be explored in the development of efficient insertion mutagenesis system. Copyright © 2013 Elsevier GmbH. All rights reserved.

75 FR 28657 - Dell Products LP-Parmer North Location, a Subsidiary of Dell, Inc., Including On-Site Leased...

Science.gov (United States)

2010-05-21

... Spherion Corporation; Round Rock, TX; Dell Products LP--Parmer North One; Austin, TX; Amended Certification... Products LP--Parmer North Location, a Subsidiary of Dell, Inc., Including On-Site Leased Workers From... Act of 1974, as amended (``Act''), 19 U.S.C. 2273, the Department of Labor issued a Certification of...

76 FR 36910 - Astoria Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas...

Science.gov (United States)

2011-06-23

... Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas Turbine Power LLC... Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas Turbine Power [[Page... subscribed docket(s). For assistance with any FERC Online service, please e-mail [email protected

Development of a methodology for conducting an integrated HRA/PRA --. Task 1, An assessment of human reliability influences during LP&S conditions PWRs

Energy Technology Data Exchange (ETDEWEB)

Luckas, W.J.; Barriere, M.T.; Brown, W.S. [Brookhaven National Lab., Upton, NY (United States); Wreathall, J. [Wreathall (John) and Co., Dublin, OH (United States); Cooper, S.E. [Science Applications International Corp., McLean, VA (United States)

1993-06-01

During Low Power and Shutdown (LP&S) conditions in a nuclear power plant (i.e., when the reactor is subcritical or at less than 10--15% power), human interactions with the plant`s systems will be more frequent and more direct. Control is typically not mediated by automation, and there are fewer protective systems available. Therefore, an assessment of LP&S related risk should include a greater emphasis on human reliability than such an assessment made for power operation conditions. In order to properly account for the increase in human interaction and thus be able to perform a probabilistic risk assessment (PRA) applicable to operations during LP&S, it is important that a comprehensive human reliability assessment (HRA) methodology be developed and integrated into the LP&S PRA. The tasks comprising the comprehensive HRA methodology development are as follows: (1) identification of the human reliability related influences and associated human actions during LP&S, (2) identification of potentially important LP&S related human actions and appropriate HRA framework and quantification methods, and (3) incorporation and coordination of methodology development with other integrated PRA/HRA efforts. This paper describes the first task, i.e., the assessment of human reliability influences and any associated human actions during LP&S conditions for a pressurized water reactor (PWR).

Antiglycopeptide Mouse Monoclonal Antibody LpMab-21 Exerts Antitumor Activity Against Human Podoplanin Through Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity.

Science.gov (United States)

Kato, Yukinari; Kunita, Akiko; Fukayama, Masashi; Abe, Shinji; Nishioka, Yasuhiko; Uchida, Hiroaki; Tahara, Hideaki; Yamada, Shinji; Yanaka, Miyuki; Nakamura, Takuro; Saidoh, Noriko; Yoshida, Kanae; Fujii, Yuki; Honma, Ryusuke; Takagi, Michiaki; Ogasawara, Satoshi; Murata, Takeshi; Kaneko, Mika K

2017-02-01

The interaction between podoplanin (PDPN) and C-type lectin-like receptor 2 (CLEC-2) is involved in tumor malignancy. We have established many monoclonal antibodies (mAbs) against human podoplanin using the cancer-specific mAb (CasMab) technology. LpMab-21, one of the mouse antipodoplanin mAbs, is of the IgG 2a subclass, and its minimum epitope was determined to be Thr76-Arg79 of the human podoplanin. Importantly, sialic acid is linked to Thr76; therefore, LpMab-21 is an antiglycopeptide mAb (GpMab). In this study, we investigated whether LpMab-21 shows antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) against human podoplanin-expressing cancer cell lines in vitro and also studied its antitumor activities using a xenograft model. LpMab-21 showed high ADCC and CDC activities against not only podoplanin-expressing Chinese hamster ovary cells but also LN319 glioblastoma cells and PC-10 lung cancer cells, both of which endogenously express podoplanin. Furthermore, LpMab-21 decreased tumor growth in vivo, indicating that LpMab-21 could be useful for antibody therapy against human podoplanin-expressing cancers.

76 FR 34692 - Astoria Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas...

Science.gov (United States)

2011-06-14

... Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas Turbine Power LLC... Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas Turbine Power LLC... notification when a document is added to a subscribed docket(s). For assistance with any FERC Online service...

The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus

DEFF Research Database (Denmark)

Gottschalk, Sanne; Ifrah, Dan; Lerche, Sandra

2013-01-01

the growth of S. aureus without ATP leakage. Instead, LP5 bound DNA and inhibited macromolecular synthesis. The binding to DNA also led to inhibition of DNA gyrase and topoisomerase IV and caused induction of the SOS response. CONCLUSIONS: Our data demonstrate that LP5 may have a dual mode of action against...

Relative expression of bacterial and host specific genes associated with probiotic survival and viability in the mice gut fed with Lactobacillus plantarum Lp91.

Science.gov (United States)

Chandran, Archana; Duary, Raj Kumar; Grover, Sunita; Batish, Virender Kumar

2013-11-07

The present investigation was aimed at studying the relative expression of atpD (a key part of F1F0-ATPase operon), bsh (bile salt hydrolase), mub (mucus-binding protein) and MUC2 (mucin) genes in mouse model for establishing the in vivo functional efficacy of Lactobacillus plantarum Lp91 (MTCC5690) by reverse transcription-quantitative PCR (RT-qPCR). The atpD gene was significantly up-regulated to 2.0, 2.4 and 3.2 folds in Lp91 after 15, 30 and 60 min transit in the stomach of mice. The maximal significant (Pstrain Lp5276 after seven days of mice feeding. Simultaneously, mub gene expression increased to 12.8 and 22.7 fold in both Lp91 and Lp5276, respectively. The expression level of MUC2 was at the level of 1.6 and 2.1 fold in the host colon on administration with Lp91 and Lp5276 feeding, respectively. Hence, the expression of atpD, bsh, mub, MUC2 could be considered as prospective and potential biomarkers for screening of novel probiotic lactobacillus strains for optimal functionality in the gut. Copyright © 2013 Elsevier GmbH. All rights reserved.

Liquid-phase problems in steam turbine LP stages

International Nuclear Information System (INIS)

Blanc-Feraud, P.

1978-01-01

Wet steam formation owing to incipient condensation in final steam turbine pressure stages results in a loss of efficiency and possible rotor blading erosion. The effects of erosion are now clearly understood and quite easily counteracted, but loss of thermodynamics, mechanical and aerodynamic efficiency is still a problem. Only the final LP stages of conventional power station plant operate with wet steam, whereas nuclear plant turbines use it to produce most of their total output [fr

75 FR 45611 - Texas Eastern Transmission LP; Notice of Application

Science.gov (United States)

2010-08-03

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP10-471-000] Texas Eastern Transmission LP; Notice of Application July 27, 2010. Take notice that on July 15, 2010, Texas Eastern Transmission (Texas Eastern), P.O. Box 1642, Houston, Texas 77251-1642, filed in Docket No. CP10-471-000, an...

Characterizing the Resolved M6 Dwarf Twin LP 318-218AB

Science.gov (United States)

Moreno Hilario, Elizabeth; Burgasser, Adam J.; Bardalez Gagliuffi, Daniella; Tamiya, Tomoki

2017-01-01

The lowest-mass stars and brown dwarfs are among the most common objects in the Milky Way Galaxy, but theories of their formation and evolution remain poorly constrained. Binary systems are important for understanding the formation of these objects and for making direct orbit and mass measurements to validate evolutionary theories. We report the discovery of LP 318-218, a high proper motion late M dwarf, as a near equal-brightness binary system with a separation of 0.72 arcseconds. Resolved near-infrared spectroscopy confirms the components as nearly identical M6 twins. We using our resolved photometry and spectroscopy to estimate the distance, projected separation and tangential velocity of the system, and confirm common proper motion. We also perform atmosphere model fits to the resolved spectra to assess their physical properties. We place LP 318-218 in context with other widely-separated late M dwarf binaries.

Safety analysis report: packages. LP-12 tritium package (packaging of fissile and other radioactive materials). Final report

International Nuclear Information System (INIS)

Gates, A.A.; McCarthy, P.G.; Edl, J.W.

1975-05-01

Elemental tritium is shipped at low pressure in a stainless steel container (LP-12) within an aluminum vessel and surrounded by 3.9 in.-thick Celotex insulation in a steel drum. Information is presented on the packaging design, evaluation of the structural, thermal, containment, shielding, and criticality characteristics of the package, procedures for loading, unloading, transporting, and testing the LP-12, and quality assurance requirements. (U.S.)

Safety and efficacy of a Labisia pumila var alata water extract on ...

African Journals Online (AJOL)

kgk-002

2014-02-05

Feb 5, 2014 ... Future research should focus on older subjects that are sexually ... large population-based study on adults ranging from ages ... Abbreviations: LP, Labisia pumila; FSFI, female sexual function index; AEs, adverse events; ALT, ...

Developing an Index of Deprivation Which Integrates Objective and Subjective Dimensions: Extending the Work of Townsend, Mack and Lansley, and Hallerod

Science.gov (United States)

Eroglu, Sebnem

2007-01-01

This article presents a new approach to index development, extending the methods used by Townsend, Mack and Lansley and Hallerod to measure deprivation in the developed world. The index combines three "objective" dimensions of deprivation (i.e. monetary, consumption and work-related), and weighs them according to subjective perceptions…

LP DAAC MEaSUREs Project Artifact Tracking Via the NASA Earthdata Collaboration Environment

Science.gov (United States)

Bennett, S. D.

2015-12-01

The Land Processes Distributed Active Archive Center (LP DAAC) is a NASA Earth Observing System (EOS) Data and Information System (EOSDIS) DAAC that supports selected EOS Community non-standard data products such as the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) Global Emissivity Database (GED), and also supports NASA Earth Science programs such as Making Earth System Data Records for Use in Research Environments (MEaSUREs) to contribute in providing long-term, consistent, and mature data products. As described in The LP DAAC Project Lifecycle Plan (Daucsavage, J.; Bennett, S., 2014), key elements within the Project Inception Phase fuse knowledge between NASA stakeholders, data producers, and NASA data providers. To support and deliver excellence for NASA data stewardship, and to accommodate long-tail data preservation with Community and MEaSUREs products, the LP DAAC is utilizing NASA's own Earthdata Collaboration Environment to bridge stakeholder communication divides. By leveraging a NASA supported platform, this poster describes how the Atlassian Confluence software combined with a NASA URS/Earthdata support can maintain each project's members, status, documentation, and artifact checklist. Furthermore, this solution provides a gateway for project communities to become familiar with NASA clients, as well as educating the project's NASA DAAC Scientists for NASA client distribution.

75 FR 76037 - HAVI Logistics, North America a Subsidiary of HAVI Group, LP Including On-Site Leased Workers of...

Science.gov (United States)

2010-12-07

... Logistics, North America a Subsidiary of HAVI Group, LP Including On-Site Leased Workers of Express Personnel Services and the La Salle Network, Bloomingdale, IL; Havi Logistics, North America, Lisle, IL..., applicable to workers of HAVI Logistics, North America, a subsidiary of HAVI Group, LP, including on-site...

77 FR 42353 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

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2012-07-18

... Regulations because Escalate Capital Partners SBIC I, L.P. proposes to Finance a small business in which its... SMALL BUSINESS ADMINISTRATION [License No. 06/06-0335] Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest...

76 FR 17180 - KLH Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment...

Science.gov (United States)

2011-03-28

... SMALL BUSINESS ADMINISTRATION [License No. 04/04-0296] KLH Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that KLH Capital, L.P., 101 East Kennedy Boulevard, Suite 3925, Tampa, FL, 33602 a Federal...

Scenario logic and probabilistic management of risk in business and engineering

CERN Document Server

Solojentsev, Evgueni D

2009-01-01

The book proposes a uniform logic and probabilistic (LP) approach to risk estimation and analysis in engineering and economics. It covers the methodological and theoretical basis of risk management at the design, test, and operation stages of economic, banking, and engineering systems with groups of incompatible events (GIE). It considers the risk LP-models in classification, investment, management of companies, bribes and corruption, analysis of risk and efficiency of social and economical processes, and management of development. Key features of this Second Edition: -Five new chapters -Treatment of the basic principles of the modern risk LP theory (the LP-calculus, the LP-methods and the risk LP-theory with GIE) using uniform methodology and terminology with a practical orientation towards both engineering and economics, for the first time in book form -Clear definitions and notations, revised sections and chapters, an extended list of references, and a new subject index -More than a hundred illustrations a...

Effect of Pitavastatin Treatment on ApoB-48 and Lp-PLA₂ in Patients with Metabolic Syndrome: Substudy of PROspective Comparative Clinical Study Evaluating the Efficacy and Safety of PITavastatin in Patients with Metabolic Syndrome.

Science.gov (United States)

Lee, Hyo Sun; Jung, Chang Hee; Kim, Sung Rae; Jang, Hak Chul; Park, Cheol Young

2016-03-01

Apolipoprotein (Apo) B-48 is an intestinally derived lipoprotein that is expected to be a marker for cardiovascular disease (CVD). Lipoprotein-associated phospholipase A₂ (Lp-PLA₂) is a vascular-specific inflammatory marker and important risk predictor of CVD. The aim of this study was to explore the effect of pitavastatin treatment and life style modification (LSM) on ApoB-48 and Lp-PLA₂ levels in metabolic syndrome (MS) patients at relatively low risk for CVD, as a sub-analysis of a previous multi-center prospective study. We enrolled 75 patients with MS from the PROPIT study and randomized them into two treatment groups: 2 mg pitavastatin daily+intensive LSM or intensive LSM only. We measured the change of lipid profiles, ApoB-48 and Lp-PLA₂ for 48 weeks. Total cholesterol, low density lipoprotein cholesterol, non-high density lipoprotein cholesterol, and ApoB-100/A1 ratio were significantly improved in the pitavastatin+LSM group compared to the LSM only group (P≤0.001). Pitavastatin+LSM did not change the level of ApoB-48 in subjects overall, but the level of ApoB-48 was significantly lower in the higher mean baseline value group of ApoB-48. The change in Lp-PLA₂ was not significant after intervention in either group after treatment with pitavastatin for 1 year. Pitavastatin treatment and LSM significantly improved lipid profiles, ApoB-100/A1 ratio, and reduced ApoB-48 levels in the higher mean baseline value group of ApoB-48, but did not significantly alter the Lp-PLA₂ levels.

Study on the mechanism and efficiency of simulated annealing using an LP optimization benchmark problem - 113

International Nuclear Information System (INIS)

Qianqian, Li; Xiaofeng, Jiang; Shaohong, Zhang

2010-01-01

Simulated Annealing Algorithm (SAA) for solving combinatorial optimization problems is a popular method for loading pattern optimization. The main purpose of this paper is to understand the underlying search mechanism of SAA and to study its efficiency. In this study, a general SAA that employs random pair exchange of fuel assemblies to search for the optimum fuel Loading Pattern (LP) is applied to an exhaustively searched LP optimization benchmark problem. All the possible LPs of the benchmark problem have been enumerated and evaluated via the use of the very fast and accurate Hybrid Harmonics and Linear Perturbation (HHLP) method, such that the mechanism of SA for LP optimization can be explicitly analyzed and its search efficiency evaluated. The generic core geometry itself dictates that only a small number LPs can be generated by performing random single pair exchanges and that the LPs are necessarily mostly similar to the initial LP. This phase space effect turns out to be the basic mechanism in SAA that can explain its efficiency and good local search ability. A measure of search efficiency is introduced which shows that the stochastic nature of SAA greatly influences the variability of its search efficiency. It is also found that using fuel assembly k-infinity distribution as a technique to filter the LPs can significantly enhance the SAA search efficiency. (authors)

78 FR 32294 - Escalate Capital Partners SBIC I, L.P., License No. 06/06-0335; Notice Seeking Exemption Under...

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2013-05-29

..., Suite 309, Austin, TX 78730. The financing is contemplated to provide working capital. The financing is... SMALL BUSINESS ADMINISTRATION Escalate Capital Partners SBIC I, L.P., License No. 06/06-0335... Notice is hereby given that Escalate Capital Partners, SBIC I, L.P., 300 W. 6th Street, Suite 2250...

76 FR 68803 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

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2011-11-07

... Courtyard Drive, Suite 309, Austin, TX 78730. The financing is contemplated to provide working capital and... SMALL BUSINESS ADMINISTRATION [License No. 06/06-0335] Escalate Capital Partners SBIC I, L.P... Notice is hereby given that Escalate Capital Partners, SBIC I, L.P., 300 W. 6th Street, Suite 2250...

Lipoprotein (a): a potential biological marker for unruptured intracranial aneurysms.

Science.gov (United States)

Phillips, J; Roberts, G; Bolger, C; el Baghdady, A; Bouchier-Hayes, D; Farrell, M; Collins, P

1997-05-01

The diagnosis and treatment of intracranial aneurysms (IAs) prior to rupture reduces the high morbidity and mortality associated with their occurrence. Elevated serum lipoprotein (a) [Lp(a)] level, an independent risk factor for atherogenesis, has been demonstrated in sporadic IA disease (1). The purpose of this study was to assess the degree of correlation between elevated Lp(a) levels and the occurrence of IAs in asymptomatic first degree relatives of index cases from three families exhibiting a familial tendency towards IA development. 25 family members and 41 healthy controls were screened by random serum Lp(a) sampling. All family members received 4-vessel cerebral angiography. Eleven family members were found on angiography to harbour asymptomatic aneurysms and all were successfully treated by surgery. Of these 11, ten had significantly raised serum Lp(a) levels (> 30 mg%). Fourteen family members had negative angiograms. Eight of this latter group, mean age 43.6 +/- 3.8 years, had serum Lp(a) levels above the normal range. Mean Lp(a) levels were 53.7 +/- 1.2 mg% in subjects with aneurysms compared with 22.1 +/- 1.45 mg% in subjects without demonstrable aneurysms and 10.5 +/- 0.48 mg% in the control population. The prevalence of elevated Lp(a) levels in these families and the high degree of association of raised Lp(a) levels with the presence of IAs in several family members warrants follow up of angiographically negative young subjects. We require a case-control study to establish whether particular polymorphisms at the apoprotein (a) gene level are associated with the occurrence of IAs in these families.

77 FR 22773 - Texas Eastern Transmission, L.P.; Notice of Response

Science.gov (United States)

2012-04-17

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [ Docket No. RP12-318-001] Texas Eastern... order of the Federal Energy Regulatory Commission in the above- captioned proceeding Texas Eastern Transmission, LP (Texas Eastern) submits its response to show cause why it should not be required to file...

TRAC-PF1 MOD1 post test calculations of the OECD LOFT Experiment LP-SB-1

International Nuclear Information System (INIS)

Allen, E.J.

1990-04-01

Analysis of the small, hot leg break, OECD LOFT Experiment LP-SB-1. using the ''best-estimate'' computer code TRAC-PF1/MOD1 is presented. Descriptions of the LOFT facility and the LP-SB-1 experiment are given and development of the TRAC-PF1/MOD1 input model is detailed. The calculations performed in achieving the steady state conditions, from which the experiment was initiated, and the specification of experimental boundary conditions are outlined. 24 refs., 66 figs., 12 tabs

Håndbog i praktisk hjælp eBog

DEFF Research Database (Denmark)

René, Michael

Håndbog i praktisk hjælp er en opslagsbog med masser af nyttig viden om rengøring, hygiejne og opbevaring af fødevarer. Bogen indeholder afsnit om forskellige rengøringsmidler, om rengøring af forskellige materialer og om fjernelse af pletter, og der er en beskrivelse af forholdsregler i forbinde......://michaelrene.com/forfatter/ Anmeldelse: http://www.michaelrene.com/Munksgaard/AnmeldelseHaandbogIpraktiskhjaelp.png...

Håndbog i praktisk hjælp iBog

DEFF Research Database (Denmark)

René, Michael

Håndbog i praktisk hjælp er en opslagsbog med masser af nyttig viden om rengøring, hygiejne og opbevaring af fødevarer. Bogen indeholder afsnit om forskellige rengøringsmidler, om rengøring af forskellige materialer og om fjernelse af pletter, og der er en beskrivelse af forholdsregler i forbinde......://michaelrene.com/forfatter/ Anmeldelse: http://www.michaelrene.com/Munksgaard/AnmeldelseHaandbogIpraktiskhjaelp.png...

The Leptospiral Antigen Lp49 is a Two-Domain Protein with Putative Protein Binding Function

Energy Technology Data Exchange (ETDEWEB)

Oliveira Giuseppe,P.; Oliveira Neves, F.; Nascimento, A.; Gomes Guimaraes, B.

2008-01-01

Pathogenic Leptospira is the etiological agent of leptospirosis, a life-threatening disease that affects populations worldwide. Currently available vaccines have limited effectiveness and therapeutic interventions are complicated by the difficulty in making an early diagnosis of leptospirosis. The genome of Leptospira interrogans was recently sequenced and comparative genomic analysis contributed to the identification of surface antigens, potential candidates for development of new vaccines and serodiagnosis. Lp49 is a membrane-associated protein recognized by antibodies present in sera from early and convalescent phases of leptospirosis patients. Its crystal structure was determined by single-wavelength anomalous diffraction using selenomethionine-labelled crystals and refined at 2.0 Angstroms resolution. Lp49 is composed of two domains and belongs to the all-beta-proteins class. The N-terminal domain folds in an immunoglobulin-like beta-sandwich structure, whereas the C-terminal domain presents a seven-bladed beta-propeller fold. Structural analysis of Lp49 indicates putative protein-protein binding sites, suggesting a role in Leptospira-host interaction. This is the first crystal structure of a leptospiral antigen described to date.

Estimating EQ-5D values from the Oswestry Disability Index and numeric rating scales for back and leg pain.

Science.gov (United States)

Carreon, Leah Y; Bratcher, Kelly R; Das, Nandita; Nienhuis, Jacob B; Glassman, Steven D

2014-04-15

Cross-sectional cohort. The purpose of this study is to determine whether the EuroQOL-5D (EQ-5D) can be derived from commonly available low back disease-specific health-related quality of life measures. The Oswestry Disability Index (ODI) and numeric rating scales (0-10) for back pain (BP) and leg pain (LP) are widely used disease-specific measures in patients with lumbar degenerative disorders. Increasingly, the EQ-5D is being used as a measure of utility due to ease of administration and scoring. The EQ-5D, ODI, BP, and LP were prospectively collected in 14,544 patients seen in clinic for lumbar degenerative disorders. Pearson correlation coefficients for paired observations from multiple time points between ODI, BP, LP, and EQ-5D were determined. Regression modeling was done to compute the EQ-5D score from the ODI, BP, and LP. The mean age was 53.3 ± 16.4 years and 41% were male. Correlations between the EQ-5D and the ODI, BP, and LP were statistically significant (P < 0.0001) with correlation coefficients of -0.77, -0.50, and -0.57, respectively. The regression equation: [0.97711 + (-0.00687 × ODI) + (-0.01488 × LP) + (-0.01008 × BP)] to predict EQ-5D, had an R2 of 0.61 and a root mean square error of 0.149. The model using ODI alone had an R2 of 0.57 and a root mean square error of 0.156. The model using the individual ODI items had an R2 of 0.64 and a root mean square error of 0.143. The correlation coefficient between the observed and estimated EQ-5D score was 0.78. There was no statistically significant difference between the actual EQ-5D (0.553 ± 0.238) and the estimated EQ-5D score (0.553 ± 0.186) using the ODI, BP, and LP regression model. However, rounding off the coefficients to less than 5 decimal places produced less accurate results. Unlike previous studies showing a robust relationship between low back-specific measures and the Short Form-6D, a similar relationship was not seen between the ODI, BP, LP, and the EQ-5D. Thus, the EQ-5D cannot be

Safety analysis report: packages. LP-50 tritium package (packaging of fissile and other radioactive materials). Final report

International Nuclear Information System (INIS)

Gates, A.A.; McCarthy, P.G.; Edl, J.W.

1975-04-01

Elemental tritium is shipped at low pressure in a stainless steel container (LP-50) sealed within an aluminum vessel and surrounded by a minimum of 4-in. thick Celotex insulation in a steel drum. The structural, thermal, containment, shielding, and criticality safety aspects of this package are evaluated. Procedures for loading and unloading, empty cask transport, acceptance testing and maintenance, and quality assurance requirements for the LP-50 package are described in detail. (U.S.)

Training Lp norm multiple kernel learning in the primal.

Science.gov (United States)

Liang, Zhizheng; Xia, Shixiong; Zhou, Yong; Zhang, Lei

2013-10-01

Some multiple kernel learning (MKL) models are usually solved by utilizing the alternating optimization method where one alternately solves SVMs in the dual and updates kernel weights. Since the dual and primal optimization can achieve the same aim, it is valuable in exploring how to perform Lp norm MKL in the primal. In this paper, we propose an Lp norm multiple kernel learning algorithm in the primal where we resort to the alternating optimization method: one cycle for solving SVMs in the primal by using the preconditioned conjugate gradient method and other cycle for learning the kernel weights. It is interesting to note that the kernel weights in our method can obtain analytical solutions. Most importantly, the proposed method is well suited for the manifold regularization framework in the primal since solving LapSVMs in the primal is much more effective than solving LapSVMs in the dual. In addition, we also carry out theoretical analysis for multiple kernel learning in the primal in terms of the empirical Rademacher complexity. It is found that optimizing the empirical Rademacher complexity may obtain a type of kernel weights. The experiments on some datasets are carried out to demonstrate the feasibility and effectiveness of the proposed method. Copyright © 2013 Elsevier Ltd. All rights reserved.

Spatiotemporal profiles of receptive fields of neurons in the lateral posterior nucleus of the cat LP-pulvinar complex.

Science.gov (United States)

Piché, Marilyse; Thomas, Sébastien; Casanova, Christian

2015-10-01

The pulvinar is the largest extrageniculate thalamic visual nucleus in mammals. It establishes reciprocal connections with virtually all visual cortexes and likely plays a role in transthalamic cortico-cortical communication. In cats, the lateral posterior nucleus (LP) of the LP-pulvinar complex can be subdivided in two subregions, the lateral (LPl) and medial (LPm) parts, which receive a predominant input from the striate cortex and the superior colliculus, respectively. Here, we revisit the receptive field structure of LPl and LPm cells in anesthetized cats by determining their first-order spatiotemporal profiles through reverse correlation analysis following sparse noise stimulation. Our data reveal the existence of previously unidentified receptive field profiles in the LP nucleus both in space and time domains. While some cells responded to only one stimulus polarity, the majority of neurons had receptive fields comprised of bright and dark responsive subfields. For these neurons, dark subfields' size was larger than that of bright subfields. A variety of receptive field spatial organization types were identified, ranging from totally overlapped to segregated bright and dark subfields. In the time domain, a large spectrum of activity overlap was found, from cells with temporally coinciding subfield activity to neurons with distinct, time-dissociated subfield peak activity windows. We also found LP neurons with space-time inseparable receptive fields and neurons with multiple activity periods. Finally, a substantial degree of homology was found between LPl and LPm first-order receptive field spatiotemporal profiles, suggesting a high integration of cortical and subcortical inputs within the LP-pulvinar complex. Copyright © 2015 the American Physiological Society.

LP turbine retrofit modernization: Improvements in performance and operation

International Nuclear Information System (INIS)

Groenedaal, J.C.; Fowls, L.G.; Subbiah, R.; Maxwell, B.P.; Persson, B.

1996-01-01

Westinghouse Electric Corporation retrofitted six low pressure (LP) nuclear turbine rotors and associated blade path components at Ringhals 1, a 1960's vintage English Electric (GEC) unit located near Varobacka, Sweden, and operated by Vattenfall AB. This achieved significant performance improvements and provided improved mechanical features over the original equipment. This paper, discusses design, manufacture, installation, operation and project coordination. The retrofit processes employed for these units can be applied to any potential customers units

A comparison of P-3 and LP-3 distribution of peak floods at guddu barrage on indus river

International Nuclear Information System (INIS)

Memon, A.G.

2007-01-01

In this paper P-3 (Pearson-3) and LP-3 (Log-Pearson-3) distributions are fitted on the data of flood peaks at Guddu, for 38 years (1962-1999), Using three methods of estimation namely MOM (Method Of Moments), KLM (Maximum Likelihood Method) and PWM (Power weighted moment). LP-3 distribution appears to be appropriate for modeling the flood data on the basis of i-test, S-K (Simirnov- Kolmogrov) test, Cs (Coefficient of Skewness), RMSE (Root Mean Square Errors), PPCC (Probability Plot Correlation Coefficient) and L-Moment Ratios. MLM is found to be the efficient method. 1.52 million cusecs flood is expected to arrive at Guddu barrage, during next 100 years, when LP-3 distribution is fitted by MLM, i.e. 37% more than its designed capacity of 1.1 million cusecs. (author)

LpMab-12 Established by CasMab Technology Specifically Detects Sialylated O-Glycan on Thr52 of Platelet Aggregation-Stimulating Domain of Human Podoplanin.

Directory of Open Access Journals (Sweden)

Yukinari Kato

Full Text Available Podoplanin (PDPN, also known as Aggrus, possesses three tandem repeat of platelet aggregation-stimulating (PLAG domains in its N-terminus. Among the PLAG domains, sialylated O-glycan on Thr52 of PLAG3 is essential for the binding to C-type lectin-like receptor-2 (CLEC-2 and the platelet-aggregating activity of human PDPN (hPDPN. Although various anti-hPDPN monoclonal antibodies (mAbs have been generated, no specific mAb has been reported to target the epitope containing glycosylated Thr52. We recently established CasMab technology to develop mAbs against glycosylated membrane proteins. Herein, we report the development of a novel anti-glycopeptide mAb (GpMab, LpMab-12. LpMab-12 detected endogenous hPDPN by flow cytometry. Immunohistochemical analyses also showed that hPDPN-expressing lymphatic endothelial and cancer cells were clearly labeled by LpMab-12. The minimal epitope of LpMab-12 was identified as Asp49-Pro53 of hPDPN. Furthermore, LpMab-12 reacted with the synthetic glycopeptide of hPDPN, corresponding to 38-54 amino acids (hpp3854: 38-EGGVAMPGAEDDVVTPG-54, which carries α2-6 sialylated N-acetyl-D-galactosamine (GalNAc on Thr52. LpMab-12 did not recognize non-sialylated GalNAc-attached glycopeptide, indicating that sialylated GalNAc on Thr52 is necessary for the binding of LpMab-12 to hPDPN. Thus, LpMab-12 could serve as a new diagnostic tool for determining whether hPDPN possesses the sialylation on Thr52, a site-specific post-translational modification critical for the hPDPN association with CLEC-2.

Fasting Ghrelin Levels Are Decreased in Obese Subjects and Are Significantly Related With Insulin Resistance and Body Mass Index

Directory of Open Access Journals (Sweden)

Dimitrios Papandreou

2017-10-01

CONCLUSION: Obese subjects have low fasting ghrelin levels that they are significantly related to insulin resistance and body mass index. More prospective studies are needed to establish the role of ghrelin in the pathogenesis of human obesity.

76 FR 17180 - C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment...

Science.gov (United States)

2011-03-28

... SMALL BUSINESS ADMINISTRATION [License No. 07/07-0113] C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that C3 Capital Partners IT, L.P., 4520 Main Street, Suite 1600, Kansas City, Missouri, 64111-7700...

77 FR 5613 - C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment...

Science.gov (United States)

2012-02-03

... SMALL BUSINESS ADMINISTRATION [License No. 07/07-0113] C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that C3 Capital Partners II, L.P., 4520 Main Street, Suite 1600, Kansas City, Missouri 64111-7700...

Serum LP(A) levels in randomized healthy men from different European countries

NARCIS (Netherlands)

Cigolini, M; Seidell, J C; Zenti, M G; Bonadonna, G; Zambelli, L; Deslypere, J P; Contaldo, F; Cruz, A.; Charzewska, J; Targher, G

Serum lipoprotein(a) [Lp(a)], blood lipids, serum insulin and anthropometric parameters were determined in randomized samples of 38-year-old men living in six European cities: Ede (The Netherlands), Deinze (Belgium), Warsaw (Poland), Lumiar (Portugal), Verona and Naples (respectively in northern and

On Some Isomorphisms between Bounded Linear Maps and Non-Commutative Lp-Spaces

Directory of Open Access Journals (Sweden)

E. J. Atto

2014-04-01

Full Text Available We define a particular space of bounded linear maps using a Von Neumann algebra and some operator spaces. By this, we prove some isomorphisms, and using interpolation in some particular cases, we get analogue of non-commutative Lp spaces.

Directory of Book Trade and Related Organizations. Books Trade Associations, United States and Canada; International and Foreign Book Trade Associations; National Information Standards Organization (NISO) Standards; Calendar, 2003-2012; Acronyms; Index of Organizations; Subject Index.

Science.gov (United States)

Bowker Annual Library and Book Trade Almanac, 2003

2003-01-01

Includes two lists: one of book trade associations in the United States and Canada, and one of international and foreign book trade associations. Concludes with National Information Standards Organization (NISO) standards; calendar, 2003-2012; acronyms; index of organizations; and subject index. (LRW)

Composition of The Knee Index, a novel three-dimensional biomechanical index for knee joint load, in subjects with mild to moderate knee osteoarthritis

DEFF Research Database (Denmark)

Clausen, Brian; Andriacchi, Tom; Nielsen, Dennis Brandborg

Background Knee joint load is an important factor associated with progression of knee osteoarthritis. To provide an overall understanding of knee joint loading, the Knee Index (KI) has been developed to include moments from all three planes (frontal, sagittal and transversal). However, before KI...... index of joint load for the knee, in patients with mild to moderate knee osteoarthritis. Methods The contribution of frontal, sagittal and transversal plane knee moments to KI was investigated in 24 subjects (13 women, age: 58 ± 7.6 years, BMI: 27.1 ± 3.0) with clinically diagnosed mild to moderate knee...... kinematics (i.e. the knee adduction moment), and secondarily the sagittal plane kinematics (i.e. the knee flexion moment). This holds promise for using KI in clinical trials since both frontal and sagittal knee joint moments have been suggested to be associated with the knee osteoarthritis disease...

Leg joint power output during progressive resistance FES-LCE cycling in SCI subjects: developing an index of fatigue

Directory of Open Access Journals (Sweden)

Faghri Pouran D

2008-04-01

Full Text Available Abstract Background The purpose of this study was to investigate the biomechanics of the hip, knee and ankle during a progressive resistance cycling protocol in an effort to detect and measure the presence of muscle fatigue. It was hypothesized that knee power output can be used as an indicator of fatigue in order to assess the cycling performance of SCI subjects. Methods Six spinal cord injured subjects (2 incomplete, 4 complete between the ages of twenty and fifty years old and possessing either a complete or incomplete spinal cord injury at or below the fourth cervical vertebra participated in this study. Kinematic data and pedal forces were recorded during cycling at increasing levels of resistance. Ankle, knee and hip power outputs and resultant pedal force were calculated. Ergometer cadence and muscle stimulation intensity were also recorded. Results The main findings of this study were: (a ankle and knee power outputs decreased, whereas hip power output increased with increasing resistance, (b cadence, stimulation intensity and resultant pedal force in that combined order were significant predictors of knee power output and (c knowing the value of these combined predictors at 10 rpm, an index of fatigue can be developed, quantitatively expressing the power capacity of the knee joint with respect to a baseline power level defined as fatigue. Conclusion An index of fatigue was successfully developed, proportionalizing knee power capacity during cycling to a predetermined value of fatigue. The fatigue index value at 0/8th kp, measured 90 seconds into active, unassisted pedaling was 1.6. This indicates initial power capacity at the knee to be 1.6 times greater than fatigue. The fatigue index decreased to 1.1 at 2/8th kp, representing approximately a 30% decrease in the knee's power capacity within a 4 minute timespan. These findings suggest that the present cycling protocol is not sufficient for a rider to gain the benefits of FES and thus

Leg joint power output during progressive resistance FES-LCE cycling in SCI subjects: developing an index of fatigue.

Science.gov (United States)

Haapala, Stephenie A; Faghri, Pouran D; Adams, Douglas J

2008-04-26

The purpose of this study was to investigate the biomechanics of the hip, knee and ankle during a progressive resistance cycling protocol in an effort to detect and measure the presence of muscle fatigue. It was hypothesized that knee power output can be used as an indicator of fatigue in order to assess the cycling performance of SCI subjects. Six spinal cord injured subjects (2 incomplete, 4 complete) between the ages of twenty and fifty years old and possessing either a complete or incomplete spinal cord injury at or below the fourth cervical vertebra participated in this study. Kinematic data and pedal forces were recorded during cycling at increasing levels of resistance. Ankle, knee and hip power outputs and resultant pedal force were calculated. Ergometer cadence and muscle stimulation intensity were also recorded. The main findings of this study were: (a) ankle and knee power outputs decreased, whereas hip power output increased with increasing resistance, (b) cadence, stimulation intensity and resultant pedal force in that combined order were significant predictors of knee power output and (c) knowing the value of these combined predictors at 10 rpm, an index of fatigue can be developed, quantitatively expressing the power capacity of the knee joint with respect to a baseline power level defined as fatigue. An index of fatigue was successfully developed, proportionalizing knee power capacity during cycling to a predetermined value of fatigue. The fatigue index value at 0/8th kp, measured 90 seconds into active, unassisted pedaling was 1.6. This indicates initial power capacity at the knee to be 1.6 times greater than fatigue. The fatigue index decreased to 1.1 at 2/8th kp, representing approximately a 30% decrease in the knee's power capacity within a 4 minute timespan. These findings suggest that the present cycling protocol is not sufficient for a rider to gain the benefits of FES and thus raises speculation as to whether or not progressive resistance

Comparison of Lp(a) concentrations and some potential effects in hemodialysis, CAPD, transplantation, and control groups, and review of the literature.

Science.gov (United States)

Gault, M H; Longerich, L L; Purchase, L; Harnett, J; Breckenridge, C

1995-01-01

Apolipoprotein (a)-Lp(a)-is reported to be an independent risk factor for coronary artery disease and for hemodialysis (HD) access occlusion. Homology with plasminogen may predispose to thrombosis. High concentrations usually have been reported in patients on HD and on continuous ambulatory peritoneal dialysis (CAPD), but near-normal values in many kidney transplants (TP). We used Pharmacia immunoradiometric assay in 52 patients on HD, 58 on CAPD, 94 after TP, and 56 controls. The Lp(a) mean levels for CAPD, HD, TP, and control groups were 738, 647, 348, and 368 U/l and the medians were 542, 537, 96 and 143 U/l, respectively. The means and medians for CAPD and HD were significantly greater than those for TP and controls (p fall 77%). The dominant Apo(a) isoform in 10 of 13 patients on CAPD or HD with high Lp(a) values was the equivalent of S2 (Utermann). Lp(a) in HD or CAPD is often elevated and regulated by both genetic and renal failure factors, but falls after TP with return of renal function and mainly genetic regulation. Lp(a) was not a risk factor for coronary artery disease in HD or CAPD patients and did not fall significantly with two drugs or diet.

Design of cladding rods-assisted depressed-core few-mode fibers with improved modal spacing

Science.gov (United States)

Han, Jiawei; Zhang, Jie

2018-03-01

This paper investigates the design details of cladding rods-assisted (CRA) depressed-core (DC) few-mode fibers (FMFs) that feature more equally spaced linearly polarized (LP) modal effective indices, suitable for high-spatial-density weakly-coupled mode-division multiplexing systems. The influences of the index profile of cladding rods on LP mode-resolved effective index, bending sensitivity, and effective area Aeff, are numerically described. Based on the design considerations of LP modal Aeff-dependent spatial efficiency and LP modal bending loss-dependent robustness, the small LP21-LP02 and LP22-LP03 modal spacing limitations, encountered in state-of-the-art weakly-coupled step-index FMFs, have been substantially improved by at least 25%. In addition, the proposed CRA DC FMFs also show sufficiently large effective areas (in excess of 110 μm2) for all guided LP modes, which are expected to exhibit good nonlinear performance.

Prospects for CW and LP operation of the European XFEL in hard X-ray regime

International Nuclear Information System (INIS)

Brinkmann, R.; Schneidmiller, E.A.; Sekutowicz, J.; Yurkov, M.V.

2014-03-01

The European XFEL will operate nominally at 17.5 GeV in SP (short pulse) mode with 0.65 ms long bunch train and 10 Hz repetition rate. A possible upgrade of the linac to CW (continuous wave) or LP (long pulse) modes with a corresponding reduction of electron beam energy is under discussion since many years. Recent successes in the dedicated R and D program allow to forecast a technical feasibility of such an upgrade in the foreseeable future. One of the challenges is to provide sub-Aangstrom FEL operation in CW and LP modes. In this paper we perform a preliminary analysis of a possible operation of the European XFEL in the hard X-ray regime in CW and LP modes with the energies of 7 GeV and 10 GeV, respectively. We consider lasing in the baseline XFEL undulator as well as in a new undulator with a reduced period. We show that, with reasonable requirements on electron beam quality, lasing on the fundamental will be possible in sub-Aangstrom regime. As an option for generation of brilliant photon beams at short wavelengths we also consider harmonic lasing that has recently attracted a significant attention.

Comparative Genomic Analysis of Lactobacillus plantarum GB-LP1 Isolated from Traditional Korean Fermented Food.

Science.gov (United States)

Yu, Jihyun; Ahn, Sojin; Kim, Kwondo; Caetano-Anolles, Kelsey; Lee, Chanho; Kang, Jungsun; Cho, Kyungjin; Yoon, Sook Hee; Kang, Dae-Kyung; Kim, Heebal

2017-08-28

As probiotics play an important role in maintaining a healthy gut flora environment through antitoxin activity and inhibition of pathogen colonization, they have been of interest to the medical research community for quite some time now. Probiotic bacteria such as Lactobacillus plantarum , which can be found in fermented food, are of particular interest given their easy accessibility. We performed whole-genome sequencing and genomic analysis on a GB-LP1 strain of L. plantarum isolated from Korean traditional fermented food; this strain is well known for its functions in immune response, suppression of pathogen growth, and antitoxin effects. The complete genome sequence of GB-LP1 is a single chromosome of 3,040,388 bp with 2,899 predicted open reading frames. Genomic analysis of GB-LP1 revealed two CRISPR regions and genes showing accelerated evolution, which may have antibiotic and antitoxin functions. The aim of the present study was to predict strain specific-genomic characteristics and assess the potential of this new strain as lactic acid bacteria at the genomic level using in silico analysis. These results provide insight into the L. plantarum species as well as confirm the possibility of its utility as a candidate probiotic.

Prospects for CW and LP operation of the European XFEL in hard X-ray regime

Energy Technology Data Exchange (ETDEWEB)

Brinkmann, R.; Schneidmiller, E.A.; Sekutowicz, J.; Yurkov, M.V.

2014-03-15

The European XFEL will operate nominally at 17.5 GeV in SP (short pulse) mode with 0.65 ms long bunch train and 10 Hz repetition rate. A possible upgrade of the linac to CW (continuous wave) or LP (long pulse) modes with a corresponding reduction of electron beam energy is under discussion since many years. Recent successes in the dedicated R and D program allow to forecast a technical feasibility of such an upgrade in the foreseeable future. One of the challenges is to provide sub-Aangstrom FEL operation in CW and LP modes. In this paper we perform a preliminary analysis of a possible operation of the European XFEL in the hard X-ray regime in CW and LP modes with the energies of 7 GeV and 10 GeV, respectively. We consider lasing in the baseline XFEL undulator as well as in a new undulator with a reduced period. We show that, with reasonable requirements on electron beam quality, lasing on the fundamental will be possible in sub-Aangstrom regime. As an option for generation of brilliant photon beams at short wavelengths we also consider harmonic lasing that has recently attracted a significant attention.

Quality of pharmacy-specific Medical Subject Headings (MeSH) assignment in pharmacy journals indexed in MEDLINE.

Science.gov (United States)

Minguet, Fernando; Salgado, Teresa M; van den Boogerd, Lucienne; Fernandez-Llimos, Fernando

2015-01-01

The Medical Subject Headings (MeSH) is the National Library of Medicine (NLM) controlled vocabulary for indexing articles. Inaccuracies in the MeSH thesaurus have been reported for several areas including pharmacy. To assess the quality of pharmacy-specific MeSH assignment to articles indexed in pharmacy journals. The 10 journals containing the highest number of articles published in 2012 indexed under the MeSH 'Pharmacists' were identified. All articles published over a 5-year period (2008-2012) in the 10 previously selected journals were retrieved from PubMed. MeSH terms used to index these articles were extracted and pharmacy-specific MeSH terms were identified. The frequency of use of pharmacy-specific MeSH terms was calculated across journals. A total of 6989 articles were retrieved from the 10 pharmacy journals, of which 328 (4.7%) were articles not fully indexed and therefore did not contain any MeSH terms assigned. Among the 6661 articles fully indexed, the mean number of MeSH terms was 10.1 (SD = 4.0), being 1.0 (SD = 1.3) considered as Major MeSH. Both values significantly varied across journals. The mean number of pharmacy-specific MeSH terms per article was 0.9 (SD = 1.2). A total of 3490 (52.4%) of the 6661 articles were indexed in pharmacy journals without a single pharmacy-specific MeSH. Of the total 67193 MeSH terms assigned to articles, on average 10.5% (SD = 13.9) were pharmacy-specific MeSH. A statistically significant different pattern of pharmacy-specific MeSH assignment was identified across journals (Kruskal-Wallis P journals can be improved to further enhance evidence gathering in pharmacy. Over half of the articles published in the top-10 journals publishing pharmacy literature were indexed without a single pharmacy-specific MeSH. Copyright © 2015 Elsevier Inc. All rights reserved.

75 FR 6200 - Equitrans, L.P.; Notice of Request Under Blanket Authorization

Science.gov (United States)

2010-02-08

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP10-46-000] Equitrans, L.P..., Monongalia, and Wetzel Counties, West Virginia and to make certain modifications to compressor engines at [email protected] or call toll-free, (866) 208-3676 or TTY, (202) 502-8659. Specifically, Equitrans...

76 FR 61682 - Panhandle Eastern Pipe Line Company, LP; Notice of Application

Science.gov (United States)

2011-10-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-546-000] Panhandle Eastern Pipe Line Company, LP; Notice of Application On September 16, 2011, Panhandle Eastern Pipe Line... free). For TTY, call (202) 502-8659. Comment Date: 5 p.m. Eastern Time on October 19, 2011. Dated...

Detailed phase matching characterization of inter-modal four-wave mixing in a two-mode fiber

DEFF Research Database (Denmark)

Friis, Søren Michael Mørk; Jung, Y.; Begleris, I.

2016-01-01

We experimentally characterize the phase matching properties of two inter-modal four-wave mixing processes in a graded index fiber guiding the LP01 and LP11 mode-groups.......We experimentally characterize the phase matching properties of two inter-modal four-wave mixing processes in a graded index fiber guiding the LP01 and LP11 mode-groups....

Optimal design for crosstalk analysis in 12-core 5-LP mode homogeneous multicore fiber for different lattice structure

Science.gov (United States)

Kumar, Dablu; Ranjan, Rakesh

2018-03-01

12-Core 5-LP mode homogeneous multicore fibers have been proposed for analysis of inter-core crosstalk and dispersion, with four different lattice structures (circular, 2-ring, square lattice, and triangular lattice) having cladding diameter of 200 μm and a fixed cladding thickness of 35 μm. The core-to-core crosstalk impact has been studied numerically with respect to bending radius, core pitch, transmission distance, wavelength, and core diameter for all 5-LP modes. In anticipation of further reduction in crosstalk levels, the trench-assisted cores have been incorporated for all respective designs. Ultra-low crosstalk (-138 dB/100 km) has been achieved through the triangular lattice arrangement, with trench depth Δ2 = -1.40% for fundamental (LP01) mode. It has been noted that the impact of mode polarization on crosstalk behavior is minor, with difference in crosstalk levels between two polarized spatial modes as ≤0.2 dB. Moreover, the optimized cladding diameter has been obtained for all 5-LP modes for a target value of crosstalk of -50 dB/100 km, with all the core arrangements. The dispersion characteristic has also been analyzed with respect to wavelength, which is nearly 2.5 ps/nm km at operating wavelength 1550 nm. The relative core multiplicity factor (RCMF) for the proposed design is obtained as 64.

Server scheduling in the Lp norm: A rising tide lifts all boat

NARCIS (Netherlands)

Bansal, N.; Pruhs, K.R.

2003-01-01

Often server systems do not implement the best known algorithms for optimizing average Quality of Service (QoS) out of concern of that these algorithms may be insufficiently fair to individual jobs. The standard method for balancing average QoS and fairness is optimize the Lp metric, 1

Dewey Decimal Classification Online Project: Evaluation of a Library Schedule and Index Integrated into the Subject Searching Capabilities of an Online Catalog. Final Report.

Science.gov (United States)

Markey, Karen; Demeyer, Anh N.

In this research project, subject terms from the Dewey Decimal Classification (DDC) Schedules and Relative Index were incorporated into an online catalog as searcher's tools for subject access, browsing, and display. Four features of the DDC were employed to help searchers browse for and match their own subject terms with the online catalog's…

76 FR 14387 - Texas Eastern Transmission, LP; Notice of Request Under Blanket Authorization

Science.gov (United States)

2011-03-16

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-118-000] Texas Eastern... Eastern Transmission, LP (Texas Eastern), Post Office Box 1642, Houston, Texas 77251-1642, filed in Docket... West Cameron Blocks 566, 565, and 548, offshore Louisiana, under Texas Eastern's blanket certificate...

Immunogenicity, Safety, and Tolerability of Bivalent rLP2086 Meningococcal Group B Vaccine Administered Concomitantly With Diphtheria, Tetanus, and Acellular Pertussis and Inactivated Poliomyelitis Vaccines to Healthy Adolescents.

Science.gov (United States)

Vesikari, Timo; Wysocki, Jacek; Beeslaar, Johannes; Eiden, Joseph; Jiang, Qin; Jansen, Kathrin U; Jones, Thomas R; Harris, Shannon L; O'Neill, Robert E; York, Laura J; Perez, John L

2016-06-01

Concomitant administration of bivalent rLP2086 (Trumenba [Pfizer, Inc] and diphtheria, tetanus, and acellular pertussis and inactivated poliovirus vaccine (DTaP/IPV) was immunologically noninferior to DTaP/IPV and saline and was safe and well tolerated. Bivalent rLP2086 elicited robust and broad bactericidal antibody responses to diverse Neisseria meningitidis serogroup B strains expressing antigens heterologous to vaccine antigens after 2 and 3 vaccinations. Bivalent rLP2086, a Neisseria meningitidis serogroup B (MnB) vaccine (Trumenba [Pfizer, Inc]) recently approved in the United States to prevent invasive MnB disease in individuals aged 10-25 years, contains recombinant subfamily A and B factor H binding proteins (fHBPs). This study evaluated the coadministration of Repevax (diphtheria, tetanus, and acellular pertussis and inactivated poliovirus vaccine [DTaP/IPV]) (Sanofi Pasteur MSD, Ltd) and bivalent rLP2086. Healthy adolescents aged ≥11 to B proteins different from the vaccine antigens. Participants were randomly assigned to receive bivalent rLP2086 + DTaP/IPV (n = 373) or saline + DTaP/IPV (n = 376). Immune responses to DTaP/IPV in participants who received bivalent rLP2086 + DTaP/IPV were noninferior to those in participants who received saline + DTaP/IPV.The proportions of bivalent rLP2086 + DTaP/IPV recipients with prespecified seroprotective hSBA titers to the 4 MnB test strains were 55.5%-97.3% after vaccination 2 and 81.5%-100% after vaccination 3. The administration of bivalent rLP2086 was well tolerated and resulted in few serious adverse events. Immune responses to DTaP/IPV administered with bivalent rLP2086 to adolescents were noninferior to DTaP/IPV administered alone. Bivalent rLP2086 was well tolerated and elicited substantial and broad bactericidal responses to diverse MnB strains in a high proportion of recipients after 2 vaccinations, and these responses were further enhanced after 3 vaccinations.ClinicalTrials.gov identifier NCT01323270

76 FR 57087 - Stone Harbor Investment Partners LP, et al.; Notice of Application

Science.gov (United States)

2011-09-15

... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 29784; File No. 812-13931] Stone Harbor Investment Partners LP, et al.; Notice of Application September 7, 2011. AGENCY: Securities..., or cause more than 10% of the acquired company's voting stock to be owned by investment companies and...

76 FR 65507 - Notice of Petition for Rate Approval; Eagle Ford Midstream, LP

Science.gov (United States)

2011-10-21

... Petition for Rate Approval; Eagle Ford Midstream, LP Take notice that on October 11, 2011, (Eagle Ford..., and its initial baseline Statement of Operating Conditions. Eagle Ford states that it is an existing..., currently providing intrastate services to its customers. Eagle Ford proposed rates for Section 311...

Evaluation of Protective Immune Responses Induced by Recombinant TrxLp and ENO2 Proteins against Toxoplasma gondii Infection in BALB/c Mice

Directory of Open Access Journals (Sweden)

Meng Wang

2016-01-01

Full Text Available Toxoplasma gondii is an obligate intracellular parasitic protozoan that can infect almost all species of warm-blooded animals. As any chemical-based drugs could not act against the tissue cyst stage of T. gondii, vaccination may be one of the ideal control strategies. In the present study, two new vaccine candidates, named TgENO2 and TgTrxLp, were purified from Escherichia coli with pET-30a(+ expression system and then were injected into BALB/c mice to evaluate the protective efficacy against acute and chronic toxoplasmosis. The results showed that both the recombinant proteins, either alone or in combination, could elicit strong humoral and cellular immune responses with a higher level of IgG antibodies, IFN-γ, IL-2, CD4+, and CD8+ T cells as compared to those in mice from control groups. After acute challenge with tachyzoites of the GJS strain, mice immunized with rTgTrxLp (8±2.77 d, rTgENO2 (7.4±1.81 d, and rTgTrxLp + rTgENO2 (8.38±4.57 d proteins showed significantly longer survival time than those that received Freund’s adjuvant (6.78±2.08 d and PBS (6.38±4.65 d (χ2 = 9.687, df = 4, P=0.046. The protective immunity of rTgTrxLp, rTgENO2, and rTgTrxLp + rTgENO2 proteins against chronic T. gondii infection showed 69.77%, 58.14%, and 20.93% brain cyst reduction as compared to mice that received PBS. The present study suggested that both TgENO2 and TgTrxLp were potential candidates for the development of multicomponent vaccines against toxoplasmosis.

The phosducin-like protein PhLP1 impacts regulation of glycoside hydrolases and light response in Trichoderma reesei

Directory of Open Access Journals (Sweden)

Tisch Doris

2011-12-01

Full Text Available Abstract Background In the biotechnological workhorse Trichoderma reesei (Hypocrea jecorina transcription of cellulase genes as well as efficiency of the secreted cellulase mixture are modulated by light. Components of the heterotrimeric G-protein pathway interact with light-dependent signals, rendering this pathway a key regulator of cellulase gene expression. Results As regulators of heterotrimeric G-protein signaling, class I phosducin-like proteins, are assumed to act as co-chaperones for G-protein beta-gamma folding and exert their function in response to light in higher eukaryotes. Our results revealed light responsive transcription of the T. reesei class I phosducin-like protein gene phlp1 and indicate a light dependent function of PhLP1 also in fungi. We showed the functions of PhLP1, GNB1 and GNG1 in the same pathway, with one major output being the regulation of transcription of glycoside hydrolase genes including cellulase genes in T. reesei. We found no direct correlation between the growth rate and global regulation of glycoside hydrolases, which suggests that regulation of growth does not occur only at the level of substrate degradation efficiency. Additionally, PhLP1, GNB1 and GNG1 are all important for proper regulation of light responsiveness during long term exposure. In their absence, the amount of light regulated genes increased from 2.7% in wild type to 14% in Δphlp1. Besides from the regulation of degradative enzymes, PhLP1 was also found to impact on the transcription of genes involved in sexual development, which was in accordance with decreased efficiency of fruiting body formation in Δphlp1. The lack of GNB1 drastically diminished ascospore discharge in T. reesei. Conclusions The heterotrimeric G-protein pathway is crucial for the interconnection of nutrient signaling and light response of T. reesei, with the class I phosducin-like protein PhLP1, GNB1 and GNG1 acting as important nodes, which influence light

75 FR 57844 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2010-09-23

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39-16438. Docket No. FAA-2010-0555... (Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200...

76 FR 65717 - Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment

Science.gov (United States)

2011-10-24

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2713-082-New York] Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment In accordance with the National Environmental Policy Act of 1969 and the Federal Energy Regulatory Commission's (Commission...

Efficacy and safety of the probiotic Lactobacillus paracasei LP-33 in allergic rhinitis

DEFF Research Database (Denmark)

Costa, D J; Marteau, P; Amouyal, M

2014-01-01

BACKGROUND/OBJECTIVES: An imbalance between Th1 and Th2 cells is involved in allergic rhinitis (AR) that may be improved by probiotics. To test the efficacy of the probiotic Lactobacillus paracasei subsp. paracasei LP-33, a double-blind, placebo-controlled, randomized trial was carried out in pat...

76 FR 25330 - Texas Eastern Transmission, LP; Notice of Request Under Blanket Authorization

Science.gov (United States)

2011-05-04

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-216-000] Texas Eastern... Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in Docket No... in the termination of any services to Texas Eastern's customers, all as more fully set forth in the...

76 FR 46287 - Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment

Science.gov (United States)

2011-08-02

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2047-049] Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment In accordance with the National Environmental Policy Act of 1969 and the Federal Energy Regulatory Commission's (Commission or FERC) regulations...

77 FR 58323 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2012-09-20

... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150 airplanes. This proposed AD was.... Discussion The Civil Aviation Authority of Israel (CAAI), which is the aviation authority for Israel, has...

77 FR 32069 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2012-05-31

... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200 airplanes. This proposed... receive about this proposed AD. Discussion The Civil Aviation Authority of Israel (CAAI), which is the...

Effect of nicotine on melanogenesis and antioxidant status in HEMn-LP melanocytes

International Nuclear Information System (INIS)

Delijewski, Marcin; Beberok, Artur; Otręba, Michał; Wrześniok, Dorota; Rok, Jakub; Buszman, Ewa

2014-01-01

Nicotine is a natural ingredient of tobacco plants and is responsible for the addictive properties of tobacco. Nowadays nicotine is also commonly used as a form of smoking cessation therapy. It is suggested that nicotine may be accumulated in human tissues containing melanin. This may in turn affect biochemical processes in human cells producing melanin. The aim of this study was to examine the effect of nicotine on melanogenesis and antioxidant status in cultured normal human melanocytes HEMn-LP. Nicotine induced concentration-dependent loss in melanocytes viability. The value of EC 50 was determined to be 7.43 mM. Nicotine inhibited a melanization process in human light pigmented melanocytes and caused alterations of antioxidant defense system. Significant changes in cellular antioxidant enzymes: superoxide dismutase and catalase activities and in hydrogen peroxide content were stated. The obtained results may explain a potential influence of nicotine on biochemical processes in melanocytes in vivo during long term exposition to nicotine. - Graphical abstract: Nicotine inhibits melanogenesis and induces oxidative stress in HEMn-LP melanocytes. - Highlights: • Nicotine induces concentration-dependent loss in melanocytes viability. • Nicotine in non-cytotoxic concentrations inhibits melanogenesis. • Nicotine in higher concentrations induces oxidative stress

Effect of nicotine on melanogenesis and antioxidant status in HEMn-LP melanocytes

Energy Technology Data Exchange (ETDEWEB)

Delijewski, Marcin; Beberok, Artur; Otręba, Michał; Wrześniok, Dorota; Rok, Jakub; Buszman, Ewa, E-mail: ebuszman@sum.edu.pl

2014-10-15

Nicotine is a natural ingredient of tobacco plants and is responsible for the addictive properties of tobacco. Nowadays nicotine is also commonly used as a form of smoking cessation therapy. It is suggested that nicotine may be accumulated in human tissues containing melanin. This may in turn affect biochemical processes in human cells producing melanin. The aim of this study was to examine the effect of nicotine on melanogenesis and antioxidant status in cultured normal human melanocytes HEMn-LP. Nicotine induced concentration-dependent loss in melanocytes viability. The value of EC{sub 50} was determined to be 7.43 mM. Nicotine inhibited a melanization process in human light pigmented melanocytes and caused alterations of antioxidant defense system. Significant changes in cellular antioxidant enzymes: superoxide dismutase and catalase activities and in hydrogen peroxide content were stated. The obtained results may explain a potential influence of nicotine on biochemical processes in melanocytes in vivo during long term exposition to nicotine. - Graphical abstract: Nicotine inhibits melanogenesis and induces oxidative stress in HEMn-LP melanocytes. - Highlights: • Nicotine induces concentration-dependent loss in melanocytes viability. • Nicotine in non-cytotoxic concentrations inhibits melanogenesis. • Nicotine in higher concentrations induces oxidative stress.

Strain and temperature characteristics of the LP11 mode based on a few-mode fiber Bragg grating and core-offset splicing

Science.gov (United States)

Jin, Wenxing; Xu, Yao; Jiang, Youchao; Wu, Yue; Yao, Shuzhi; Xiao, Shiying; Qi, Yanhui; Ren, Wenhua; Jian, Shuisheng

2018-02-01

We propose and demonstrate a ring fiber laser based on a few-mode fiber Bragg grating for strain and temperature sensing using only the LP11 mode. The core-offset splicing method is used to ensure effective coupling from the fundamental mode to the LP11 mode. A stable erbium-doped fiber laser operating as a single LP11 mode with a 3 dB linewidth of about 0.02 nm and an optical signal-to-noise ratio over 42 dB is achieved by appropriately adjusting the polarization controller between the optical circulator and the few-mode fiber Bragg grating. A high axial strain sensitivity of 0.8778 pm μ\\varepsilon-1 and a temperature sensitivity of 9.9214 pm °C-1 are achieved with the advantages of all-fiber, simple construction and easy control.

Indexes to Nuclear Regulatory Commission issuances, July--December 1992

International Nuclear Information System (INIS)

1993-06-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index; Digests and Legal Citations Index, Subject Index, and Facility Index. Subject words and/or phrases arranged alphabetically, indicate the issues and subjects covered in the issuances. The subject headings are followed by phrases that give specific information about the subject, as discussed in the issuances being indexed. These phrases are followed by the issuance number and the full text reference

76 FR 41432 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2011-07-14

... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Galaxy, Gulfstream... proposed AD. Discussion The Civil Aviation Authority (CAA), which is the aviation authority for Israel, has... Held by Israel Aircraft Industries, Ltd.): Docket No. FAA-2011-0716; Directorate Identifier 2011-NM-013...

75 FR 36296 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2010-06-25

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... contact we receive about this proposed AD. Discussion The Civil Aviation Authority of Israel (CAAI), which is the aviation authority for Israel, has issued Israeli Airworthiness Directive 01-10-01-07R1, dated...

The Effects of Curcuma longa L., Purple Sweet Potato, and Mixtures of the Two on Immunomodulation in C57BL/6J Mice Infected with LP-BM5 Murine Leukemia Retrovirus.

Science.gov (United States)

Park, Soo-Jeung; Lee, Dasom; Lee, Minhee; Kwon, Han-Ol; Kim, Hyesook; Park, Jeongjin; Jeon, Woojin; Cha, Minseok; Jun, Suhwa; Park, Kwangjin; Lee, Jeongmin

2018-06-04

The immune response is stimulated to protect the body from external antigens and is controlled by several types of immune cells. In the present study, the immunomodulatory effects of Curcuma longa L., purple sweet potato, and mixtures of the two (CPM) were investigated in C57BL/6 mice infected with LP-BM5 murine leukemia virus (MuLV). Mice were divided into seven groups as follows: normal control, infected control (LP-BM5 MuLV infection), positive control (LP-BM5 MuLV infection+dietary supplement of red ginseng 300 mg/kg body weight), the original powder of C. longa L. (C; LP-BM5 MuLV infection+dietary supplement of C 189 mg/kg body weight), the original powder of purple sweet potato (P; LP-BM5 MuLV infection+dietary supplement of P 1811 mg/kg body weight), CPM Low (CPL; LP-BM5 MuLV infection+CPM 2 g/kg body weight), and CPM High (CPH; LP-BM5 MuLV infection+CPM 5 g/kg body weight). Dietary supplementation lasted for 12 weeks. Dietary supplementation of CPM inhibited LP-BM5 MuLV-induced lymphadenopathy and splenomegaly and inhibited reduction of messenger RNA (mRNA) expression of major histocompatibility complex (MHC) I and II. Moreover, CPM reduced the decrease in T- and B cell proliferation, reduced the population of CD4(+)/CD8(+) T cells, and remedied the unbalanced production of T helper-1 (Th1)/T helper-2 (Th2) cytokines in LP-BM5 MuLV-infected mice. In addition, CPM inhibited reduction of phagocytosis in peritoneal macrophages and decreased serum levels of immunoglobulin A (IgA), immunoglobulin E (IgE), and immunoglobulin G (IgG). These results suggest that CPM had a positive effect on immunomodulation in C57BL/6 mice induced by LP-BM5 leukemia retrovirus infection.

Increased hepatic cholesterol esterification with essential fatty acid deficiency (EFAD): relationship to plasma lipoprotein (LP) cholesterol content

International Nuclear Information System (INIS)

Ney, D.M.; Ziboh, V.A.; Schneeman, B.O.

1986-01-01

EFAD in the rat is associated with hepatic accumulation of esterified cholesterol and altered distribution of cholesterol between plasma and hepatic tissue. Little is known regarding the impact of EFAD on LP composition. To determine the relationship between hepatic cholesterol esterification and plasma lP composition in control (C) and EFAD male Wistar rats, the authors induced EFAD with continuous intragastric (IG) infusion of EFA-free solutions containing 3.5% of calories as triolein for 7 and 14 days. C animals received IG infusion of solutions containing 3.5% of calories as linoleic acid. Data in the EFAD groups reveal: (i) marked decreases in hepatic EFAs and increases in monoenoic acids; (ii) progressive increases in hepatic content of triglyceride and esterified cholesterol with 7 and 14 days of feeding; (iii) assay of acyl CoA:cholesterol acyltransferase activity in hepatic tissue using 14 C-cholesterol demonstrates an increase in hepatic cholesterol esterification when compared to C animals. Increased hepatic cholesterol esterification correlates with elevated levels of esterified cholesterol in plasma VLDL and HDL particles. These data indicate that the elevated levels of cholesterol esters in LP particles is due, at least in part, to increased hepatic cholesterol esterification with EFAD

76 FR 70438 - Enterprise Intrastate L.P., Enterprise Texas Pipeline LLC; Notice of Filing

Science.gov (United States)

2011-11-14

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR12-4-000; Docket No. PR12-5-000; Not Consolidated] Enterprise Intrastate L.P., Enterprise Texas Pipeline LLC; Notice of Filing Take notice that on November 1, 2011, the applicants listed above filed a revised Statement of...

Concomitant effects of Ramadan fasting and time-of-day on apolipoprotein AI, B, Lp-a and homocysteine responses during aerobic exercise in Tunisian soccer players.

Directory of Open Access Journals (Sweden)

Omar Hammouda

Full Text Available OBJECTIVE: To examine the time-of-day and Ramadan fasting (RF effects on serum apolipoprotein-AI (Apo-AI and B (Apo-B, lipoprotein particles-a (Lp-a, high-sensitive C-reactive-protein (hs-CRP, and homocysteine (Hcy during the Yo-Yo intermittent recovery test (YYIRT. DESIGN: Performance and biochemical measures were completed at two times-of-day (07:00 and 17:00 h, 1-week before RF (BR, the second week of RF (SWR, and the fourth week of RF (ER. SETTING: For each session, subjects performed the YYIRT, and blood samples were taken before and 3-min after the test for biochemical measures. PARTICIPANTS: Fifteen soccer players. MAIN OUTCOME MEASURES: Total distance during the YYIRT, core temperature, body composition, dietary intakes, lipid (HDL-C, LDL-C, Apo-AI, B and Lp-a and inflammatory (hs-CRP and Hcy profiles. RESULTS: Performances during the YYIRT were higher in the evening than the morning BR (P < 0.05, but this fluctuation was not observed during RF. Moreover, LDL-C, ApoB, and Lp-a were stable throughout the daytime BR. However, during RF, they decreased at 17:00 h (P < 0.05. Likewise, HDL-C and Apo-AI increased after the exercise and were higher at 17:00 h BR (P < 0.001. Moreover, these parameters increased during RF (P < 0.01. Furthermore, Hcy and hs-CRP increased during the exercise (P < 0.01 with higher evening levels BR. During ER, the diurnal pattern of Hcy was inversed (P < 0.001. CONCLUSIONS: This study concluded that caloric restriction induced by RF seems to ameliorate lipid and inflammatory markers of cardiovascular health during intermittent exercise performed in the evening.

Remarks on the Phragmen-Lindelof theorem for Lp-viscosity solutions of fully nonlinear PDEs with unbounded ingredients

Directory of Open Access Journals (Sweden)

Kazushige Nakagawa

2009-11-01

Full Text Available The Phragmen-Lindelof theorem for Lp-viscosity solutions of fully nonlinear second order elliptic partial differential equations with unbounded coefficients and inhomogeneous terms is established.

On- and off-response ERGs elicited by sawtooth stimuli in normal subjects and glaucoma patients.

Science.gov (United States)

Pangeni, Gobinda; Lämmer, Robert; Tornow, Ralf P; Horn, Folkert K; Kremers, Jan

2012-06-01

The aim of this study is to measure the on- and off-responses and their response asymmetries elicited by sawtooth stimuli in normal subjects and glaucoma patients. Furthermore, the correlation between the ERGs and other functional and structural parameters are investigated. Full-field stimuli were produced using a Ganzfeld bowl with Light Emitting Diodes (LEDs) as light sources. On- and off-response ERGs were recorded from 17 healthy subjects, 12 pre-perimetric and 15 perimetric glaucoma patients using 4-Hz luminance rapid-on and rapid-off sawtooth stimuli (white light; mean luminance 55 cd/m(2)) at 100% contrast. The on- and off-responses were added to study response asymmetries. In addition, flash ERGs were elicited by red stimuli (200 cd/m(2)) on a blue background (10 cd/m(2)). The mean deviations (MD) of the visual field defects were obtained by standard automated perimetry. The retinal nerve fibre layer thickness (RNFLT) was measured with Spectral Domain Optical Coherence Tomography (SOCT). We studied the correlation between ERG response amplitudes, visual field mean deviation (MDs) and RNFLT values. The on-responses showed an initial negative (N-on) followed by a positive (P-on), a late positive (LP-on) and a late negative responses (LN-on). The off-responses showed an initial positive (P-off) a late positive (LP-off) and a late negative response (LN-off). The addition of on- and off-responses revealed an initial positive (P-add) and a late negative response (LN-add). The on-response components (N-on, P-on and LN-on) in the glaucoma patients were relatively similar to those of the control subjects. However, the LP-on was significantly elevated (p = 0.03) in perimetric patients. The LP-off was significantly elevated (p < 0.001), and the amplitude of LN-off was significantly reduced in perimetric patients (p = 0.02). The LN-add amplitude was significantly reduced (p < 0.001) and delayed (p = 0.03) in perimetric patients. The amplitudes of the LN-off and LN

Indexes to Nuclear Regulatory Commission issuances, January-June 1986. Volume 23, Index 2

International Nuclear Information System (INIS)

1986-01-01

Digests and indexes for issuances of the Commission, the Atomic Safety and Licensing Appeal Panel, the Atomic Safety and Licensing Board Panel, the Administrative Law Judge, the Directors' Decisions, and the Denials of Petitions of Rulemaking are presented in this document. The information elements are displayed in one or more of five separate formats. These formats are case name index, digests and headers, legal citations index, subject index, and facility index

47 CFR 74.1204 - Protection of FM broadcast, FM Translator and LP100 stations.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Protection of FM broadcast, FM Translator and... SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1204 Protection of FM broadcast, FM Translator and LP100 stations. (a) An application for an FM translator station will not be...

Manual for subject analysis

International Nuclear Information System (INIS)

2002-01-01

This document is one in a series of publications known as the ETDE/INIS Joint Reference Series and also constitutes a part of the ETDE Procedures Manual. It presents the rules, guidelines and procedures to be adopted by centers submitting input to the International Nuclear Information System (INIS) or the Energy Technology Data Exchange (ETDE). It is a manual for the subject analysis part of input preparation, meaning the selection, subject classification, abstracting and subject indexing of relevant publications, and is to be used in conjunction with the Thesauruses, Subject Categories documents and the documents providing guidelines for the preparation of abstracts. The concept and structure of the new manual are intended to describe in a logical and efficient sequence all the steps comprising the subject analysis of documents to be reported to INIS or ETDE. The manual includes new chapters on preparatory analysis, subject classification, abstracting and subject indexing, as well as rules, guidelines, procedures, examples and a special chapter on guidelines and examples for subject analysis in particular subject fields. (g.t.; a.n.)

Sensitivity analysis for CORSOR models simulating fission product release in LOFT-LP-FP-2 severe accident experiment

Energy Technology Data Exchange (ETDEWEB)

Hoseyni, Seyed Mohsen [Islamic Azad Univ., Tehran (Iran, Islamic Republic of). Dept. of Basic Sciences; Islamic Azad Univ., Tehran (Iran, Islamic Republic of). Young Researchers and Elite Club; Pourgol-Mohammad, Mohammad [Sahand Univ. of Technology, Tabriz (Iran, Islamic Republic of). Dept. of Mechanical Engineering; Yousefpour, Faramarz [Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of)

2017-03-15

This paper deals with simulation, sensitivity and uncertainty analysis of LP-FP-2 experiment of LOFT test facility. The test facility simulates the major components and system response of a pressurized water reactor during a LOCA. MELCOR code is used for predicting the fission product release from the core fuel elements in LOFT LP-FP-2 experiment. Moreover, sensitivity and uncertainty analysis is performed for different CORSOR models simulating release of fission products in severe accident calculations for nuclear power plants. The calculated values for the fission product release are compared under different modeling options to the experimental data available from the experiment. In conclusion, the performance of 8 CORSOR modeling options is assessed for available modeling alternatives in the code structure.

Complete cumulative index (1963-1983)

International Nuclear Information System (INIS)

1983-01-01

This complete cumulative index covers all regular and special issues and supplements published by Atomic Energy Review (AER) during its lifetime (1963-1983). The complete cumulative index consists of six Indexes: the Index of Abstracts, the Subject Index, the Title Index, the Author Index, the Country Index and the Table of Elements Index. The complete cumulative index supersedes the Cumulative Indexes for Volumes 1-7: 1963-1969 (1970), and for Volumes 1-10: 1963-1972 (1972); this Index also finalizes Atomic Energy Review, the publication of which has recently been terminated by the IAEA

Indexes to Nuclear Regulatory Commission issuances, January--June 1995. Volume 41, Index 2

International Nuclear Information System (INIS)

1995-09-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the directors' Decisions (DD), and the Denials of Petitions for rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. The information elements are displayed in one or more of five separate formats arranged as follows: Case name index; digests and headers; legal citations index; subject index; and facility index

Indexes to Nuclear Regulatory Commission issuances, January-March 1984. Volume 19, Index 1

International Nuclear Information System (INIS)

1984-01-01

Digests and indexes for issuances of the Commission, the Atomic Safety and Licensing Appeal Panel, the Atomic Safety and Licensing Board Panel, the Administrative Law Judge, the Directors' Decisions, and the Denials of Petitions of Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements are displayed in one or more of five separate formats: Case Name Index, Digests and Headers, Legal Citations Index, Subject Index, and Facility Index

Indexes to Nuclear Regulatory Commission Issuances, July--December 1993. Volume 38, Index 2

Energy Technology Data Exchange (ETDEWEB)

1994-04-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors` Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index; Digests and Headers; Legal Citations Index; Subject Index, and Facility Index.

Indexes to Nuclear Regulatory Commission issuances, January--June 1995. Volume 41, Index 2

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-09-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the directors` Decisions (DD), and the Denials of Petitions for rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. The information elements are displayed in one or more of five separate formats arranged as follows: Case name index; digests and headers; legal citations index; subject index; and facility index.

Indexes to Nuclear Regulatory Commission issuances, January-June 1984. Vol. 19, Index 2

International Nuclear Information System (INIS)

1984-11-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions of Rulemaking are presented in this document. The information elements are displayed in one or more of five separate formats: case name index, digests and headers, legal citations index, subject index, and facility index

The physiological cost index of walking with a powered knee-ankle-foot orthosis in subjects with poliomyelitis: A pilot study.

Science.gov (United States)

Arazpour, Mokhtar; Ahmadi Bani, Monireh; Samadian, Mohammad; Mousavi, Mohammad E; Hutchins, Stephen W; Bahramizadeh, Mahmood; Curran, Sarah; Mardani, Mohammad A

2016-08-01

A powered knee-ankle-foot orthosis was developed to provide restriction of knee flexion during stance phase and active flexion and extension of the knee during swing phase of gait. The purpose of this study was to determine its effect on the physiological cost index, walking speed and the distance walked in people with poliomyelitis compared to when walking with a knee-ankle-foot orthosis with drop lock knee joints. Quasi experimental study. Seven subjects with poliomyelitis volunteered for the study and undertook gait analysis with both types of knee-ankle-foot orthosis. Walking with the powered knee-ankle-foot orthosis significantly reduced walking speed (p = 0.015) and the distance walked (p = 0.004), and also, it did not improve physiological cost index values (p = 0.009) compared to walking with the locked knee-ankle-foot orthosis. Using a powered knee-ankle-foot orthosis did not significantly improve any of the primary outcome measures during walking for poliomyelitis subjects. This powered knee-ankle-foot orthosis design did not improve the physiological cost index of walking for people with poliomyelitis when compared to walking with a knee-ankle-foot orthosis with drop lock knee joints. This may have been due to the short training period used or the bulky design and additional weight of the powered orthosis. Further research is therefore warranted. © The International Society for Prosthetics and Orthotics 2015.

77 FR 73089 - Cambria Investment Management, L.P. and Cambria ETF Trust; Notice of Application

Science.gov (United States)

2012-12-07

... Investment Management, L.P. and Cambria ETF Trust; Notice of Application November 30, 2012. AGENCY... (e) certain registered management investment companies and unit investment trusts outside of the same... Jennifer L. Sawin, Branch Chief, at (202) 551-6821 (Division of Investment Management, Office of Investment...

77 FR 74884 - Cambria Investment Management, L.P. and Cambria ETF Trust; Notice of Application

Science.gov (United States)

2012-12-18

... Investment Management, L.P. and Cambria ETF Trust; Notice of Application December 12, 2012. AGENCY... request an order that permits: (a) Actively-managed series of certain open-end management investment... registered management investment companies and unit investment trusts outside of the same group of investment...

Writing and the 'Subject'

DEFF Research Database (Denmark)

Greve, Charlotte

/page. It is, moreover, an index pointing to the painting/writing subject; it is a special deictic mode of painting/writing. The handwriting of the Russian avant-garde books, the poetics of handwriting, and the way handwriting is represented in poetry emphasize the way the subject (the speaking and the viewing...... in the early as well as the contemporary avant-garde, it becomes clear that the ‘subject’ is an unstable category that can be exposed to manipulation and play. Handwriting is performing as a signature (as an index), but is at the same time similar to the signature of a subject (an icon) and a verbal construct...

77 FR 66651 - Salient Advisors, L.P. and MarketShares ETF Trust; Notice of Application

Science.gov (United States)

2012-11-06

... Advisors, L.P. and MarketShares ETF Trust; Notice of Application October 31, 2012 AGENCY: Securities and... ETF Trust (the ``Trust''). Summary of Application: Applicants request an order that permits: (a... statutory trust. The Trust will initially offer one series, the Salient MLP and Energy Infrastructure ETF...

75 FR 65467 - Enterprise Alabama Intrastate, LLC; Enterprise Intrastate L.P; Notice of Baseline Filings

Science.gov (United States)

2010-10-25

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR11-4-000; Docket No. PR11-5-000; Not Consolidated] Enterprise Alabama Intrastate, LLC; Enterprise Intrastate L.P; Notice of Baseline Filings October 18, 2010. Take notice that on October 15, 2010, the applicants listed above...

Implementing and analyzing the multi-threaded LP-inference

Science.gov (United States)

Bolotova, S. Yu; Trofimenko, E. V.; Leschinskaya, M. V.

2018-03-01

The logical production equations provide new possibilities for the backward inference optimization in intelligent production-type systems. The strategy of a relevant backward inference is aimed at minimization of a number of queries to external information source (either to a database or an interactive user). The idea of the method is based on the computing of initial preimages set and searching for the true preimage. The execution of each stage can be organized independently and in parallel and the actual work at a given stage can also be distributed between parallel computers. This paper is devoted to the parallel algorithms of the relevant inference based on the advanced scheme of the parallel computations “pipeline” which allows to increase the degree of parallelism. The author also provides some details of the LP-structures implementation.

The lipid- and lipoprotein- [LDL-Lp(a)] apheresis techniques. Updating.

Science.gov (United States)

Stefanutti, C; Morozzi, C; Perrone, G; Di Giacomo, S; Vivenzio, A; D'Alessandri, G

2012-01-01

Therapeutic plasmapheresis allows the extracorporeal removal of plasmatic lipoproteins (Lipid-apheresis) (LA). It can be non selective (non specific), semi - selective or selective low density lipoprotein-lipoprotein(a) (specific [LDL- Lp(a)] apheresis) (Lipoprotein apheresis, LDLa). The LDL removal rate is a perfect parameter to assess the system efficiency. Plasma-Exchange (PEX) cannot be considered either specific nor, selective. In PEX the whole blood is separated into plasma and its corpuscular components usually through centrifugation or rather filtration. The corpuscular components mixed with albumin solution plus saline (NaCl 0.9%) solution at 20%-25%, are then reinfused to the patient, to substitute the plasma formerly removed. PEX eliminates atherogenic lipoproteins, but also other essential plasma proteins, such as albumin, immunoglobulins, and hemocoagulatory mediators. Cascade filtration (CF) is a method based on plasma separation and removal of plasma proteins through double filtration. During the CF two hollow-fiber filters with pores of different diameter are used to eliminate the plasma components of different weight and molecular diameter. A CF system uses a first polypropylene filter with 0.55 µm diameter pores and a second one of diacetate of cellulose with 0.02 µm pores. The first filter separates the whole blood, and the plasma is then perfused through a second filter which allows the recovery of molecules with a diameter lower than 0.02 µm, and the removal of molecules larger in diameter as apoB100-containing lipoproteins. Since both albumin and immunoglobulins are not removed, or to a negligible extent, plasma-expanders, substitution fluids, and in particular albumin, as occurs in PEX are not needed. CF however, is characterized by lower selectivity since removes also high density lipoprotein (HDL) particles which have an antiatherogenic activity. In the 80's, a variation of Lipid-apheresis has been developed which allows the LDL

78 FR 42889 - Pipeline Safety: Reminder of Requirements for Utility LP-Gas and LPG Pipeline Systems

Science.gov (United States)

2013-07-18

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 192 [Docket No. PHMSA-2013-0097] Pipeline Safety: Reminder of Requirements for Utility LP-Gas and LPG Pipeline Systems AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION...

76 FR 71014 - Idaho Power Company, IDACORP Energy, L.P., IDACORP, Inc.; Notice of Petition

Science.gov (United States)

2011-11-16

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. IN03-9-000] Idaho Power Company, IDACORP Energy, L.P., IDACORP, Inc.; Notice of Petition Take notice that on September 9, 2011..., 2003,\\1\\ filed a petition to terminate Appendix B, Appendix C, and Appendix E to the Settlement...

77 FR 30589 - SteelRiver Infrastructure Partners LP, SteelRiver Infrastructure Associates LLC, SteelRiver...

Science.gov (United States)

2012-05-23

... will acquire all of the common stock of Patriot from Patriot Rail Holdings LLC, and thereby indirect... America LP, and Patriot Funding LLC--Control Exemption--Patriot Rail Corp., et al. SteelRiver... notice of exemption to acquire control of Patriot Rail Corp. (Patriot) and its rail carrier subsidiaries...

Postirradiation examination results from the LP-FP-2 center fuel module

International Nuclear Information System (INIS)

Jensen, S.M.; Akers, D.W.

1990-01-01

The LP-FP-2 experiment was conducted on July 9, 1985 in the Loss of Fluid Test (LOFT) facility located at the Idaho National Engineering Laboratory (INEL). The primary purpose of this experiment was to provide information of the release, transport, and deposition of fission products and aerosols during a sever core damage event performed in a large scale nuclear reactor facility. Postirradiation nondestructive and destructive examinations of the fuel bundle provided information to assist in achieving this objective, as well as providing information on the material behavior and interactions that occurred within the fuel bundle during this sever core damage experiment. This was a large-scale integral test, incorporating an 11 x 11 array of fuel rods, control rods, and instrumentation tubes, with an active core length of 1.68 m. Peak temperatures in the fuel bundle exceeded 2100 K or approximately 4.5 min, with localized peak temperatures exceeding the melting point of the UO 2 fuel (3120 K). Large amounts of zircaloy oxidation and material relocation occurred during the experiment. The transient phase was terminated by a rapid reflood of cooling water, which resulted in significant oxidation and hydrogen generation. Zircaloy oxidation during the reflood period caused a rapid temperature excursion to occur in the upper two-thirds of the fuel bundle. This article summarizes the data and analysis from the postirradiation examinations of the LP-FP-2 fuel bundle. 12 refs., 39 figs., 8 tabs

Listening to people to cure people: the LpCp - tool, an instrument to evaluate hospital humanization.

Science.gov (United States)

Buffoli, M; Bellini, E; Bellagarda, A; Di Noia, M; Nickolova, M; Capolongo, S

2014-01-01

In the healthcare environment, nowadays, only a few among the available evaluation systems pay enough attention to certain social sustainability aspects. Among these, humanization plays a key role in an environment, like hospitals, where the mental and physical well-being of patients and healthcare operators is crucial. Our research project, known as 'SustHealth', is focused on the deficiencies of the evaluation methodology and aims at developing an assessment system related to a questionnaire-based investigation capable of revealing the most influential conditions and dynamics in people's hospital experience, while also recommending areas in hospitals where efforts can be made to sustain improvement strategies. The humanization of healthcare structures began with a significant investigation to assess all the major evaluation tools in both hospitals - to better understand the physical and emotional interactions in the structure-user ratio - and other areas. This helped understand the strengths and criticalities of the systems that were examined. This first step also allowed to shed light on the most important aspects to keep in mind when developing an evaluation system. During the operational steps an all-new LpCp - tool (Listening to people to Cure people) was created, which includes a questionnaire-based investigation and processing software, and its application for beta-testing in a 600-bed hospital in Milan. The LpCp - tool proved to be effective and capable of finding the deficiencies and potential in the examined hospital. Considering different themes through alternative viewpoints (staff, patients/visitors, technicians, etc.), the tool has allowed underlining different perceptions of the same place and also provided sound information to guide healthcare management in taking informed decisions about specific problems or users. Former interesting results show an inadequate appraisal about e.g. on-site facilities or recreational activities and a lack of

Objective and Subjective Attractiveness and Early Adolescent Adjustment.

Science.gov (United States)

Jovanovic, Jasna; And Others

1989-01-01

Used data from Pennsylvania Early Adolescent Transitions Study to assess how objective physical attractiveness (PA), indexed by appraisals from others, and subjective PA, indexed by self-appraisals, related to each other and to early adolescent adjustment. Findings indicated low relationship between objective and subjective PA; only subjective PA…

78 FR 69147 - Ranger Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application

Science.gov (United States)

2013-11-18

...] Ranger Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application November 12... Application: Applicants request an order that would permit (a) certain open-end management investment... Units; and (e) certain registered management investment companies and unit investment trusts outside of...

Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome.

Science.gov (United States)

Szymula, Agnieszka; Palermo, Richard D; Bayoumy, Amr; Groves, Ian J; Ba Abdullah, Mohammed; Holder, Beth; White, Robert E

2018-02-01

The Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) is the first viral latency-associated protein produced after EBV infection of resting B cells. Its role in B cell transformation is poorly defined, but it has been reported to enhance gene activation by the EBV protein EBNA2 in vitro. We generated EBNA-LP knockout (LPKO) EBVs containing a STOP codon within each repeat unit of internal repeat 1 (IR1). EBNA-LP-mutant EBVs established lymphoblastoid cell lines (LCLs) from adult B cells at reduced efficiency, but not from umbilical cord B cells, which died approximately two weeks after infection. Adult B cells only established EBNA-LP-null LCLs with a memory (CD27+) phenotype. Quantitative PCR analysis of virus gene expression after infection identified both an altered ratio of the EBNA genes, and a dramatic reduction in transcript levels of both EBNA2-regulated virus genes (LMP1 and LMP2) and the EBNA2-independent EBER genes in the first 2 weeks. By 30 days post infection, LPKO transcription was the same as wild-type EBV. In contrast, EBNA2-regulated cellular genes were induced efficiently by LPKO viruses. Chromatin immunoprecipitation revealed that EBNA2 and the host transcription factors EBF1 and RBPJ were delayed in their recruitment to all viral latency promoters tested, whereas these same factors were recruited efficiently to several host genes, which exhibited increased EBNA2 recruitment. We conclude that EBNA-LP does not simply co-operate with EBNA2 in activating gene transcription, but rather facilitates the recruitment of several transcription factors to the viral genome, to enable transcription of virus latency genes. Additionally, our findings suggest that EBNA-LP is essential for the survival of EBV-infected naïve B cells.

Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome

Science.gov (United States)

Szymula, Agnieszka; Palermo, Richard D.; Bayoumy, Amr; Groves, Ian J.

2018-01-01

The Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) is the first viral latency-associated protein produced after EBV infection of resting B cells. Its role in B cell transformation is poorly defined, but it has been reported to enhance gene activation by the EBV protein EBNA2 in vitro. We generated EBNA-LP knockout (LPKO) EBVs containing a STOP codon within each repeat unit of internal repeat 1 (IR1). EBNA-LP-mutant EBVs established lymphoblastoid cell lines (LCLs) from adult B cells at reduced efficiency, but not from umbilical cord B cells, which died approximately two weeks after infection. Adult B cells only established EBNA-LP-null LCLs with a memory (CD27+) phenotype. Quantitative PCR analysis of virus gene expression after infection identified both an altered ratio of the EBNA genes, and a dramatic reduction in transcript levels of both EBNA2-regulated virus genes (LMP1 and LMP2) and the EBNA2-independent EBER genes in the first 2 weeks. By 30 days post infection, LPKO transcription was the same as wild-type EBV. In contrast, EBNA2-regulated cellular genes were induced efficiently by LPKO viruses. Chromatin immunoprecipitation revealed that EBNA2 and the host transcription factors EBF1 and RBPJ were delayed in their recruitment to all viral latency promoters tested, whereas these same factors were recruited efficiently to several host genes, which exhibited increased EBNA2 recruitment. We conclude that EBNA-LP does not simply co-operate with EBNA2 in activating gene transcription, but rather facilitates the recruitment of several transcription factors to the viral genome, to enable transcription of virus latency genes. Additionally, our findings suggest that EBNA-LP is essential for the survival of EBV-infected naïve B cells. PMID:29462212

Energy data base: subject thesaurus

International Nuclear Information System (INIS)

Redford, J.S.

1981-10-01

The technical staff of the DOE Technical Information Center, during its subject indexing activities, develops and structures a vocabulary that allows consistent machine storage and retrieval of information necessary to the accomplishment of the DOE mission. This thesaurus incorporates that structured vocabulary. The terminology of this thesaurus is used for the subject control of information announced in DOE Energy Research Abstracts, Energy Abstracts for Policy Analysis, and various update journals and bulletins in specialized areas. This terminology also facilitates subject searching of the DOE Energy Data Base on the DOE/RECON on-line retrieval system and on other commercial retrieval systems. The rapid expansion of the DOE's activities will result in a commitant thesaurus expansion as information relating to new activities is indexed. Only the terms used in the indexing of documents at the Technical Information Center to date are included

Large-scale international validation of the ADO index in subjects with COPD

DEFF Research Database (Denmark)

Puhan, Milo A; Hansel, Nadia N; Sobradillo, Patricia

2012-01-01

BACKGROUND: Little evidence on the validity of simple and widely applicable tools to predict mortality in patients with chronic obstructive pulmonary disease (COPD) exists. OBJECTIVE: To conduct a large international study to validate the ADO index that uses age, dyspnoea and FEV(1) to predict 3......-IV. MEASUREMENTS: We validated the original ADO index. We then obtained an updated ADO index in half of our cohorts to improve its predictive accuracy, which in turn was validated comprehensively in the remaining cohorts using discrimination, calibration and decision curve analysis and a number of sensitivity......-to-moderate risk of 3-year mortality than FEV(1) alone. INTERPRETATION: The updated 15-point ADO index accurately predicts 3-year mortality across the COPD severity spectrum and can be used to inform patients about their prognosis, clinical trial study design or benefit harm assessment of medical interventions....

Spatiotemporal changes of normalized difference vegetation index (NDVI) and response to climate extremes and ecological restoration in the Loess Plateau, China

Science.gov (United States)

Zhao, Anzhou; Zhang, Anbing; Liu, Xianfeng; Cao, Sen

2018-04-01

Extreme drought, precipitation, and other extreme climatic events often have impacts on vegetation. Based on meteorological data from 52 stations in the Loess Plateau (LP) and a satellite-derived normalized difference vegetation index (NDVI) from the third-generation Global Inventory Modeling and Mapping Studies (GIMMS3g) dataset, this study investigated the relationship between vegetation change and climatic extremes from 1982 to 2013. Our results showed that the vegetation coverage increased significantly, with a linear rate of 0.025/10a ( P NDVI revealed an increasing trend from the northwest to the southeast, with about 61.79% of the LP exhibiting a significant increasing trend ( P NDVI at the yearly time scale ( P NDVI during the spring and autumn ( P NDVI and RX1day, TMAXmean, TXn, and TXx was insignificant in summer. Vegetation exhibited a significant negative relationship with precipitation extremes in winter ( P NDVI in Yan'an and Yulin during 1998-2013, r = 0.859 and 0.85, n = 16, P < 0.001.

78 FR 17389 - Texas Eastern Transmission, LP; Notice of Application for Certificate of Public Convenience and...

Science.gov (United States)

2013-03-21

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket Nos. CP13-84-000; PF12-19-000] Texas Eastern Transmission, LP; Notice of Application for Certificate of Public Convenience and Necessity and Authorization for Abandonment Take notice that on February 27, 2013, Texas Eastern...

78 FR 66892 - BASF Plant Science LP; Availability of Plant Pest Risk Assessment and Environmental Assessment...

Science.gov (United States)

2013-11-07

.... Kevin Shea, Administrator, Animal and Plant Health Inspection Service. [FR Doc. 2013-26701 Filed 11-6-13... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2012-0028] BASF Plant Science LP; Availability of Plant Pest Risk Assessment and Environmental Assessment for...

75 FR 71122 - Erie Boulevard Hydropower L.P.; Notice of Scoping Meetings and Environmental Site Review

Science.gov (United States)

2010-11-22

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 7518-012--New York] Erie Boulevard Hydropower L.P.; Notice of Scoping Meetings and Environmental Site Review November 15, 2010. Commission staff will be conducting two public scoping meetings and an environmental site review in support...

Evaluation of smoothing in an iterative lp-norm minimization algorithm for surface-based source localization of MEG

Science.gov (United States)

Han, Jooman; Sic Kim, June; Chung, Chun Kee; Park, Kwang Suk

2007-08-01

The imaging of neural sources of magnetoencephalographic data based on distributed source models requires additional constraints on the source distribution in order to overcome ill-posedness and obtain a plausible solution. The minimum lp norm (0 temporal gyrus.

75 FR 13755 - Freeport LNG Development, L.P.; Application To Amend Blanket Authorization To Export Liquefied...

Science.gov (United States)

2010-03-23

... Delaware limited partnership with one general partner, Freeport LNG-GP, Inc., a Delaware corporation, which...). Freeport LNG's limited partners are: (1) Freeport LNG Investments, LLLP, a Delaware limited liability limited partnership, which owns a 45% limited partnership interest in Freeport LNG; (2) Cheniere FLNG, L.P...

Influence of Peripheral Artery Disease and Statin Therapy on Apolipoprotein Profiles

Directory of Open Access Journals (Sweden)

Andrew W. Gardner

2013-01-01

Full Text Available Apolipoprotein B is a stronger predictor of myocardial infarction than LDL cholesterol, and it is inversely related to physical activity and modifiable with exercise training. As such, apolipoprotein measures may be of particular relevance for subjects with PAD and claudication. We compared plasma apolipoprotein profiles in 29 subjects with peripheral artery disease (PAD and intermittent claudication and in 39 control subjects. Furthermore, we compared the plasma apolipoprotein profiles of subjects with PAD either treated (n=17 or untreated (n=12 with statin medications. For the apolipoprotein subparticle analyses, subjects with PAD had higher age-adjusted Lp-B:C (P<0.05 and lower values of Lp-A-I:A-II (P<0.05 than controls. The PAD group taking statins had lower age-adjusted values for apoB (P<0.05, Lp-A-II:B:C:D:E (P<0.05, Lp-B:E + Lp-B:C:E (P<0.05, Lp-B:C (P<0.05, and Lp-A-I (P<0.05 than the untreated PAD group. Subjects with PAD have impaired apolipoprotein profiles than controls, characterized by Lp-B:C and Lp-A-I:A-II. Furthermore, subjects with PAD on statin medications have a more favorable risk profile, particularly noted in multiple apolipoprotein subparticles. The efficacy of statin therapy to improve cardiovascular risk appears more evident in the apolipoprotein sub-particle profile than in the more traditional lipid profile of subjects with PAD and claudication. This trial is registered with ClinicalTrials.gov NCT00618670.

76 FR 63918 - Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint

Science.gov (United States)

2011-10-14

... and Marketing Company v. SFPP, L.P.; Notice of Complaint Take notice that on October 5, 2011, pursuant... section 1(13) of the Interstate Commerce Act (ICA), 49 U.S.C. App. 13(1), Tesoro Refining and Marketing... document is added to a subscribed docket(s). For assistance with any FERC Online service, please e-mail...

Coupled-Flow Simulation of HP-LP Turbines Has Resulted in Significant Fuel Savings

Science.gov (United States)

Veres, Joseph P.

2001-01-01

Our objective was to create a high-fidelity Navier-Stokes computer simulation of the flow through the turbines of a modern high-bypass-ratio turbofan engine. The simulation would have to capture the aerodynamic interactions between closely coupled high- and low-pressure turbines. A computer simulation of the flow in the GE90 turbofan engine's high-pressure (HP) and low-pressure (LP) turbines was created at GE Aircraft Engines under contract with the NASA Glenn Research Center. The three-dimensional steady-state computer simulation was performed using Glenn's average-passage approach named APNASA. The areas upstream and downstream of each blade row mutually interact with each other during engine operation. The embedded blade row operating conditions are modeled since the average passage equations in APNASA actively include the effects of the adjacent blade rows. The turbine airfoils, platforms, and casing are actively cooled by compressor bleed air. Hot gas leaks around the tips of rotors through labyrinth seals. The flow exiting the high work HP turbines is partially transonic and, therefore, has a strong shock system in the transition region. The simulation was done using 121 processors of a Silicon Graphics Origin 2000 (NAS 02K) cluster at the NASA Ames Research Center, with a parallel efficiency of 87 percent in 15 hr. The typical average-passage analysis mesh size per blade row was 280 by 45 by 55, or approx.700,000 grid points. The total number of blade rows was 18 for a combined HP and LP turbine system including the struts in the transition duct and exit guide vane, which contain 12.6 million grid points. Design cycle turnaround time requirements ran typically from 24 to 48 hr of wall clock time. The number of iterations for convergence was 10,000 at 8.03x10(exp -5) sec/iteration/grid point (NAS O2K). Parallel processing by up to 40 processors is required to meet the design cycle time constraints. This is the first-ever flow simulation of an HP and LP

Influence of body mass index on short-term subjective improvement and risk of reoperation after mid-urethral sling surgery

DEFF Research Database (Denmark)

Weltz, Vibeke; Guldberg, Rikke; Larsen, Michael D.

2018-01-01

Introduction and hypothesis: The objective was to evaluate the impact of body mass index (BMI) on the subjective improvement and risk of reoperation after first-time mid-urethral sling surgery. Methods: Data were retrieved from the national Danish Urogynaecological Database, including women...... was defined as any new surgical procedure for stress urinary incontinence performed within the study period. Results: During the study period, 6,414 mid-urethral sling procedures were performed; 80.0% of these women filled out both pre- and post-surgical International Consultation on Incontinence...

Indexes to Nuclear Regulatory Commission issuance, July-December 1980. Index of Volume 12, Number 4

International Nuclear Information System (INIS)

1980-01-01

Issuances of the Atomic Safety and Licensing Board (ASLB), the Atomic Safety and Licensing Appeal Boards (ALAB), the Administrative Law Judge (ALJ), regulatory issuances of the Commission (CLI), the Directors Denial (DD), and the Denials of Petitions for Rulemaking for the period July through December 1980 appear in Nuclear Regulatory Commission Issuances, 12 NRC No. 1, Pages 1-136, through 12 NRC No. 6, Pages 607-742. Digests and indexes for these issuances are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements common to the cases heard and ruled upon are: Case name (owners of facility); Name of facility, docket number; Type of hearing (for construction permit, operating licenses, etc.); Issues raised by appellants; Issuance number; Type of issuance (memorandum, order, decision, etc.); Issuance pagination; Legal citations (cases, regulations, and statutes); and Subject matter of issues and/or rulings. These information elements are displayed in one or more of five separate formats arranged as follows: Case name index; Digests and headers; Legal citation index; Subject index; and Facility index

77 FR 52018 - Oxy Midstream Strategic Development, LLC, Magellan Midstream Partners, L.P.; Notice of Petition...

Science.gov (United States)

2012-08-28

... Strategic Development, LLC, Magellan Midstream Partners, L.P.; Notice of Petition for Declaratory Order Take... will transport crude oil from the Permian Basin, which is sourced in West Texas and New Mexico, to the... available for review in the Commission's Public Reference Room in Washington, DC. There is an eSubscription...

Responsiveness and minimum important change of the Oswestry Disability Index in Italian subjects with symptomatic lumbar spondylolisthesis.

Science.gov (United States)

Vanti, Carla; Ferrari, Silvano; Villafañe, Jorge Hugo; Berjano, Pedro; Monticone, Marco

2017-06-01

This study aims to investigate the responsiveness and the minimum important change of the Italian version of the Oswestry Disability Index (ODI-I) in subjects with symptomatic specific low back pain associated with lumbar spondylolisthesis (SPL). One hundred and fifty-one patients with symptomatic SPL completed the ODI-I, a 0-100 numerical rating scale (NRS), and performed the prone and supine bridge tests. The global perception of effectiveness was measured with a 7-point Likert scale. Responsiveness was assessed by distribution methods (minimum detectable change [MDC], effect size [ES], standardized response mean [SRM]) and anchor-based methods (ROC curves). The MDC was 4.23, the ES was 0.95 and the SRM was 1.25. ROC analysis revealed an area under the curve of 0.76 indicating moderate discriminating capacity. The best cut-off point for the dichotomous outcome was 7.5 (sensitivity 90.3%, specificity 56.7%). . The ODI-I proved to be responsive in detecting changes after conservative treatment in subjects with lumbar SPL. II.

Significant decrease of saturation index in erythrocytes membrane from subjects with non-alcoholic fatty liver disease (NAFLD).

Science.gov (United States)

Notarnicola, Maria; Caruso, Maria Gabriella; Tutino, Valeria; Bonfiglio, Caterina; Cozzolongo, Raffaele; Giannuzzi, Vito; De Nunzio, Valentina; De Leonardis, Giampiero; Abbrescia, Daniela I; Franco, Isabella; Intini, Vincenza; Mirizzi, Antonella; Osella, Alberto R

2017-08-23

The lipidomic profiling of erythrocyte membranes is expected to provide a peculiar scenario at molecular level of metabolic and nutritional pathways which may influence the lipid balance and the adaptation and homeostasis of the organism. Considering that lipid accumulation in the cell is important in promoting tissue inflammation, the purpose of this study is to analyze the fatty acid profile in red blood cell membranes of patients with Non-Alcoholic Fatty Liver Disease (NAFLD), in order to identify and validate membrane profiles possibly associated with the degree of hepatic damage. This work presents data obtained at baseline from 101 subjects that participated to a nutritional trial (registration number: NCT02347696) enrolling consecutive subjects with NAFLD. Diagnosis of liver steatosis was performed by using vibration-controlled elastography implemented on FibroScan. Fatty acids, extracted from phospholipids of erythrocyte membranes, were quantified by gas chromatography method. The subjects with severe NAFLD showed a significant decrease of the ratio of stearic acid to oleic acid (saturation index, SI) compared to controls, 1.281 ± 0.31 vs 1.5 ± 0.29, respectively. Low levels of SI in red blood cell membranes, inversely associated with degree of liver damage, suggest that an impairment of circulating cell membrane structure can reflect modifications that take place in the liver. Subjects with severe NAFLDalso showed higher levels of elongase 5 enzymatic activity, evaluated as vaccenic acid to palmitoleic acid ratio. Starting from these evidences, our findings show the importance of lipidomic approach in the diagnosis and the staging of NAFLD.

Nonlinear optics in the LP(02) higher-order mode of a fiber.

Science.gov (United States)

Chen, Y; Chen, Z; Wadsworth, W J; Birks, T A

2013-07-29

The distinct disperion properties of higher-order modes in optical fibers permit the nonlinear generation of radiation deeper into the ultraviolet than is possible with the fundamental mode. This is exploited using adiabatic, broadband mode convertors to couple light efficiently from an input fundamental mode and also to return the generated light to an output fundamental mode over a broad spectral range. For example, we generate visible and UV supercontinuum light in the LP(02) mode of a photonic crystal fiber from sub-ns pulses with a wavelength of 532 nm.

Automatic inference of indexing rules for MEDLINE

Directory of Open Access Journals (Sweden)

Shooshan Sonya E

2008-11-01

Full Text Available Abstract Background: Indexing is a crucial step in any information retrieval system. In MEDLINE, a widely used database of the biomedical literature, the indexing process involves the selection of Medical Subject Headings in order to describe the subject matter of articles. The need for automatic tools to assist MEDLINE indexers in this task is growing with the increasing number of publications being added to MEDLINE. Methods: In this paper, we describe the use and the customization of Inductive Logic Programming (ILP to infer indexing rules that may be used to produce automatic indexing recommendations for MEDLINE indexers. Results: Our results show that this original ILP-based approach outperforms manual rules when they exist. In addition, the use of ILP rules also improves the overall performance of the Medical Text Indexer (MTI, a system producing automatic indexing recommendations for MEDLINE. Conclusion: We expect the sets of ILP rules obtained in this experiment to be integrated into MTI.

Stakeholder participation for the legacy ponds and legacy silos (LP and LS) facility at Sellafield, Cumbria. UK: the nature and effectiveness of the dialogue - 16030

International Nuclear Information System (INIS)

Whitton, John

2009-01-01

The Legacy Ponds and Silos (LP and S) facilities are part of the UK nuclear legacy located at the Sellafield Site, Cumbria. There are four individual facilities containing nuclear wastes that have accumulated over a period of approximately 50 years. Waste retrieval and conditioning, in preparation for decommissioning, is currently being carried out by the site operator. LP and S have recently proposed a re-engagement with stakeholders following the initial engagement in December 2005. This paper reviews this earlier engagement in terms of the nature of dialogue that was carried out when compared against definitions of deliberation provided in the literature. The aim of this paper is to provide those planning future engagement with a better understanding of how the nature of dialogue can vary and uses participation and deliberation as indicators of effective engagement. A concern of those working towards a programme of effective stakeholder participation in 2005 was how to ensure genuine dialogue and stakeholder representation in such a strictly controlled and regulated environment with a technical complexity that challenges technical specialist and lay person alike. LP and S recognised that effective dialogue with stakeholders on the available technical options and their associated societal impacts would form a significant part of this process if options were to prove resilient. However, the challenge presented to LP and S was how to engage stakeholders on a variety of projects, whilst ensuring the output could be used by the projects as part of their technical decision making. Initial contact was made with stakeholders in December 2005, as part of a 'Baseline' Best Practicable Environmental Option (BPEO) study. A BPEO study leads to decisions on waste management based on an integrated assessment of alternative options, on the basis of factors such as the occupational and environmental risks, the environmental impacts, costs and social implications of the options

7 CFR 1770.3 - Index of records.

Science.gov (United States)

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Index of records. 1770.3 Section 1770.3 Agriculture... Index of records. (a) Each borrower shall maintain a master index of records. The master index shall... maintained. The master index shall be subject to review by RUS and RUS shall reserve the right to add records...

Indexes to Nuclear Regulatory Commission Issuances

International Nuclear Information System (INIS)

1996-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and licensing Board Panel (LBP), the Administrative Law Judges (ALJ) the Directors' Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index; Headers and Digests; Legal Citations Index; Subject Index; and Facility Index

Indexes to Nuclear Regulatory Commission Issuances

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and licensing Board Panel (LBP), the Administrative Law Judges (ALJ) the Directors` Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index; Headers and Digests; Legal Citations Index; Subject Index; and Facility Index.

78 FR 77770 - Aldine Capital Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

Science.gov (United States)

2013-12-24

... financing to Koontz-Wagner Maintenance Services, LLC., 3801 Voorde Drive, South Bend, IN 46628. The....P. is an Associate of Aldine Capital Fund II, L.P. and owns more than ten percent of Koontz- Wagner...

'LDL-C' = LDL-C + Lp(a)-C: implications of achieved ultra-low LDL-C levels in the proprotein convertase subtilisin/kexin type 9 era of potent LDL-C lowering.

Science.gov (United States)

Yeang, Calvin; Witztum, Joseph L; Tsimikas, Sotirios

2015-06-01

The measurement that is termed 'LDL-cholesterol' (LDL-C) includes the cholesterol content of lipoprotein(a) [Lp(a)-C], which can contribute approximately 30-45% to measured LDL-C levels as a percentage of its mass. We review the implications of achieved very low LDL-C levels in patients treated with potent LDL-C-lowering agents in the context of varying Lp(a) levels. Combination therapy with statins, ezetimibe, and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors can lower LDL-C to unprecedentedly low levels. Recent PCSK9 trials have shown that routine achievement of mean LDL-C less than 50 mg/dl is feasible, along with the modest reductions in Lp(a). Many patients will achieve LDL-C less than 25 mg/dl with concomitantly elevated Lp(a) levels that contribute substantially to the measured 'LDL-C'. Therefore, it is possible that some of these patients may have little to no circulating LDL-C. As the new era of ultralow LDL-C levels ensues, it is imperative to understand the contribution of Lp(a)-C to measured LDL-C and the consequences of achieving ultralow or potentially absent LDL-C in the setting of elevated Lp(a) levels and possibly free apo(a). We review this concept and suggest avenues of research, including analyses of existing datasets in current clinical trials and new research studies, to understand its pathophysiological and clinical significance.

Assessment of core damage models in SCDAP/RELAP5 during OECD LOFT LP-FP-2

International Nuclear Information System (INIS)

Coryell, E.W.

1991-01-01

The US Nuclear Regulatory Commission has sponsored a program to apply the SCDAP/RELAP5 code to analysis of the transient and reflood phases of the OECD LOFT LP-FP-2 Experiment. The principal objectives of the LP-FP-2 experiment were to determine the fission product release from the fuel during the early phases of a severe fuel damage scenario and to examine the phenomena controlling fission product transport in a vapor/aerosol environment. Calculations with the SCDAP/RELAP5 code, developed at the INEL with NRC support, have been performed to (1) examine the phenomena controlling the progression of both transient and reflood phases of the experiment, (2) enhance our understanding of the phenomena occurring during reflood and add credence to the postulated phenomenological sequence, (3) assess the ability of SCDAP/RELAP5 to examine severe fuel damage issues and phenomena, and (4) identify code strengths and deficiencies with the intent of prioritizing code improvements. Results indicate that the code is able to analyze the early phases of severe fuel damage reasonably well, with potential deficiencies in modelling interaction between molten control rod material and intact fuel

Fatty acid composition of adipose tissue triglycerides after weight loss and weight maintenance

DEFF Research Database (Denmark)

Kunešová, M; Hlavatý, P; Tvrzická, E

2012-01-01

Fatty acid composition of adipose tissue changes with weight loss. Palmitoleic acid as a possible marker of endogenous lipogenesis or its functions as a lipokine are under debate. Objective was to assess the predictive role of adipose triglycerides fatty acids in weight maintenance in participants...... of the DIOGENES dietary intervention study. After an 8-week low calorie diet (LCD) subjects with > 8 % weight loss were randomized to 5 ad libitum weight maintenance diets for 6 months: low protein (P)/low glycemic index (GI) (LP/LGI), low P/high GI (LP/HGI), high P/low GI (HP/LGI), high P/high GI (HP....../HGI), and a control diet. Fatty acid composition in adipose tissue triglycerides was determined by gas chromatography in 195 subjects before the LCD (baseline), after LCD and weight maintenance. Weight change after the maintenance phase was positively correlated with baseline adipose palmitoleic (16:1n-7...

75 FR 39244 - Arizona Public Service Company, Sequent Energy Management, L.P.; Notice of Joint Petition for...

Science.gov (United States)

2010-07-08

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-45-000] Arizona Public Service Company, Sequent Energy Management, L.P.; Notice of Joint Petition for Clarification, or in the Alternative, Request for Limited Waiver June 30, 2010. Take notice that on June 25, 2010, Arizona Public...

76 FR 59682 - Erie Boulevard Hydropower L.P.; Notice of Dispute Resolution Panel Meeting and Technical Conference

Science.gov (United States)

2011-09-27

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 7518-012] Erie Boulevard Hydropower L.P.; Notice of Dispute Resolution Panel Meeting and Technical Conference On September 16, 2011, Commission staff, in response to the filing of notice of study dispute by the New York State Department of...

Methods for semi-automated indexing for high precision information retrieval

Science.gov (United States)

Berrios, Daniel C.; Cucina, Russell J.; Fagan, Lawrence M.

2002-01-01

OBJECTIVE: To evaluate a new system, ISAID (Internet-based Semi-automated Indexing of Documents), and to generate textbook indexes that are more detailed and more useful to readers. DESIGN: Pilot evaluation: simple, nonrandomized trial comparing ISAID with manual indexing methods. Methods evaluation: randomized, cross-over trial comparing three versions of ISAID and usability survey. PARTICIPANTS: Pilot evaluation: two physicians. Methods evaluation: twelve physicians, each of whom used three different versions of the system for a total of 36 indexing sessions. MEASUREMENTS: Total index term tuples generated per document per minute (TPM), with and without adjustment for concordance with other subjects; inter-indexer consistency; ratings of the usability of the ISAID indexing system. RESULTS: Compared with manual methods, ISAID decreased indexing times greatly. Using three versions of ISAID, inter-indexer consistency ranged from 15% to 65% with a mean of 41%, 31%, and 40% for each of three documents. Subjects using the full version of ISAID were faster (average TPM: 5.6) and had higher rates of concordant index generation. There were substantial learning effects, despite our use of a training/run-in phase. Subjects using the full version of ISAID were much faster by the third indexing session (average TPM: 9.1). There was a statistically significant increase in three-subject concordant indexing rate using the full version of ISAID during the second indexing session (p < 0.05). SUMMARY: Users of the ISAID indexing system create complex, precise, and accurate indexing for full-text documents much faster than users of manual methods. Furthermore, the natural language processing methods that ISAID uses to suggest indexes contributes substantially to increased indexing speed and accuracy.

Bureau of Radiological Health publications index

International Nuclear Information System (INIS)

1979-08-01

The Key Word in Context (KWIC) index to the publications of the Bureau of Radiological Health was prepared to aid in the retrieval and identification of publications originated or authored by Bureau staff or published by the Bureau. These publications include journal articles, government publications and technical reports, selected staff papers, and Bureau news releases issued by HEW. For convenience, the document is divided into four sections, KWIC Index, Author Index, Bibliography Index, and BRH Publications Subject Index

Occupation as a factor of personality subjective wellbeing.

Directory of Open Access Journals (Sweden)

Karapetyan L.V.

2015-06-01

Full Text Available This article examines personality subjective well-being and describes its psychological structure, general components and characteristics. An overview of foreign theories and studies on subjective well-being is presented. Correlations among related concepts such as happiness, life satisfaction and subjective well-being are also described. Subjective well-being is seen as a multivariate construction of a stable nature in mobile equilibrium. It is argued that a type of professional activity can have great importance and a positive impact on an individual’s social life, health, identity shaping and psychological wellness. This article’s findings are substantiated by the survey administered to 2229 respondents divided into groups according to their area of business: students, psychologists, doctors, teachers, engineering and technical staff, representatives of service industries, workers, military men, and prisoners. The descriptors identified two types of natures: positive, directed to a person’s inner world (happy, lucky, optimistic and to the outer world (trustworthy, competent, successful, and negative (pessimistic, unhappy, envious. This division of nature type was categorized according to the participants’ subjective well-being index. Empirical evidence has shown that occupational specificity influences a person’s subjective well-being. A substantial difference was found in subjective well-being index of the respondents. A higher index is typical of students and military men. Educators and industrial intelligentsia also demonstrate an increased level of subjective well-being, whereas prisoners tend to have a low level of subjective well-being. The same low index is characteristic of servicing trade representatives and psychologists.

78 FR 54886 - Texas Eastern Transmission, LP; Notice of Intent To Prepare an Environmental Assessment for the...

Science.gov (United States)

2013-09-06

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PF13-15-000] Texas Eastern Transmission, LP; Notice of Intent To Prepare an Environmental Assessment for the Planned Ohio Pipeline Energy Network Project, Request for Comments on Environmental Issues, and Notice of Public Scoping Meetings The staff of the Federal Energy...

76 FR 77583 - Vantage Pipeline US LP; Notice of Intent To Prepare an Environmental Assessment and Request for...

Science.gov (United States)

2011-12-13

... DEPARTMENT OF STATE [Public Notice 7728] Vantage Pipeline US LP; Notice of Intent To Prepare an... Section 106 of the National Historic Preservation Act for the Proposed Vantage Pipeline Project December 9... (EA) that will discuss the environmental impacts of the Vantage Pipeline Project involving...

The impact of active stakeholder involvement on recruitment, retention and engagement of schools, children and their families in the cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP): a school-based intervention to prevent obesity.

Science.gov (United States)

Lloyd, J; McHugh, C; Minton, J; Eke, H; Wyatt, K

2017-08-14

Recruitment and retention of participants is crucial for statistical power and internal and external validity and participant engagement is essential for behaviour change. However, many school-based interventions focus on programme content rather than the building of supportive relationships with all participants and tend to employ specific standalone strategies, such as incentives, to improve retention. We believe that actively involving stakeholders in both intervention and trial design improves recruitment and retention and increases the chances of creating an effective intervention. The Healthy Lifestyles Programme, HeLP (an obesity prevention programme for children 9-10 years old) was developed using intervention mapping and involved extensive stakeholder involvement in both the design of the trial and the intervention to ensure that: (i) delivery methods were suitably engaging, (ii) deliverers had the necessary skills and qualities to build relationships and (iii) the intervention dovetailed with the National Curriculum. HeLP was a year-long intervention consisting of 4 multi-component phases using a range of delivery methods. We recruited 1324 children from 32 schools from the South West of England to a cluster-randomised controlled trial to determine the effectiveness of HeLP in preventing obesity. The primary outcome was change in body mass index standard deviation score (BMI SDS) at 24 months post randomisation. Secondary outcomes included additional anthropometric and behavioural (physical activity and diet) measures at 18 and 24 months. Anthropometric and behavioural measures were taken in 99%, 96% and 94% of children at baseline, 18 and 24 months, respectively, with no differential follow up between the control and intervention groups at each time point. All children participated in the programme and 92% of children and 77% of parents across the socio-economic spectrum were considered to have actively engaged with HeLP. We attribute our excellent

Dynamics of inflammatory markers in post-acute stroke patients undergoing rehabilitation.

Science.gov (United States)

Manolescu, Bogdan Nicolae; Berteanu, Mihai; Dumitru, Luminița; Dinu, Horațiu; Iliescu, Alina; Fărcășanu, Ileana Cornelia; Oprea, Eliza; Vlădoiu, Suzana; Popa, Oana; Ianăș, Olga

2011-12-01

Stroke is a pathological condition associated with an enhanced inflammatory response that has a multifactorial etiology. We evaluated the dynamic of plasma concentrations of IL-1α, IL-6, IL-8, TNF-α, soluble form of intercellular adhesion molecule 1, and lipoprotein (a) [Lp(a)] during the rehabilitation of post-acute stroke patients (n = 20), in parallel with control subjects (n = 24). Stroke patients had significantly increased concentrations of IL-6, TNF-α, and Lp(a) when compared to healthy controls. It was found that the changes in the IL-6, IL-8, and TNF-α concentrations associated with the pathological condition were statistically significant (χ2 = 4.81, p = 0.028, χ2 = 10.40, p = 0.005 and χ2 = 6.73, p = 0.034, respectively). The decrease of Lp(a) during the rehabilitation had statistical significance (p = 0.043), while the decrease of IL-1α had marginal significance (p = 0.071). IL-1α, TNF-α, and Lp(a) concentrations were significantly negatively correlated with the Barthel index values, suggesting that the decrease of these inflammatory markers was beneficial for patients' recovery.

L_p- and S_{p,q}^rB-discrepancy of (order 2) digital nets

OpenAIRE

Markhasin, Lev

2014-01-01

Dick proved that all order $2$ digital nets satisfy optimal upper bounds of the $L_2$-discrepancy. We give an alternative proof for this fact using Haar bases. Furthermore, we prove that all digital nets satisfy optimal upper bounds of the $S_{p,q}^r B$-discrepancy for a certain parameter range and enlarge that range for order $2$ digitals nets. $L_p$-, $S_{p,q}^r F$- and $S_p^r H$-discrepancy is considered as well.

Integrating theory and data to create an online self-management programme for adults with type 2 diabetes: HeLP-Diabetes

Directory of Open Access Journals (Sweden)

Kingshuk Pal

2015-10-01

This protocol demonstrates a multi-disciplinary approach to combining evidence from multiple sources to create ’HeLP-Diabetes’: a theory and evidence based online self-management intervention for adults with type 2 diabetes.

Composite Estimation for Single-Index Models with Responses Subject to Detection Limits

KAUST Repository

Tang, Yanlin; Wang, Huixia Judy; Liang, Hua

2017-01-01

We propose a semiparametric estimator for single-index models with censored responses due to detection limits. In the presence of left censoring, the mean function cannot be identified without any parametric distributional assumptions, but the quantile function is still identifiable at upper quantile levels. To avoid parametric distributional assumption, we propose to fit censored quantile regression and combine information across quantile levels to estimate the unknown smooth link function and the index parameter. Under some regularity conditions, we show that the estimated link function achieves the non-parametric optimal convergence rate, and the estimated index parameter is asymptotically normal. The simulation study shows that the proposed estimator is competitive with the omniscient least squares estimator based on the latent uncensored responses for data with normal errors but much more efficient for heavy-tailed data under light and moderate censoring. The practical value of the proposed method is demonstrated through the analysis of a human immunodeficiency virus antibody data set.

Composite Estimation for Single-Index Models with Responses Subject to Detection Limits

KAUST Repository

Tang, Yanlin

2017-11-03

We propose a semiparametric estimator for single-index models with censored responses due to detection limits. In the presence of left censoring, the mean function cannot be identified without any parametric distributional assumptions, but the quantile function is still identifiable at upper quantile levels. To avoid parametric distributional assumption, we propose to fit censored quantile regression and combine information across quantile levels to estimate the unknown smooth link function and the index parameter. Under some regularity conditions, we show that the estimated link function achieves the non-parametric optimal convergence rate, and the estimated index parameter is asymptotically normal. The simulation study shows that the proposed estimator is competitive with the omniscient least squares estimator based on the latent uncensored responses for data with normal errors but much more efficient for heavy-tailed data under light and moderate censoring. The practical value of the proposed method is demonstrated through the analysis of a human immunodeficiency virus antibody data set.

76 FR 77580 - Contemporary Healthcare Senior Lien Fund I, LP; Notice Seeking Exemption Under Section 312 of the...

Science.gov (United States)

2011-12-13

... closing costs and for working capital purposes. The financing is brought within the purview of Sec. 107... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0649] Contemporary Healthcare Senior Lien Fund I, LP; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of...

78 FR 57444 - Eagle Fund III-A, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

Science.gov (United States)

2013-09-18

... the Small Business Investment Act of 1958, as amended (the ``Act''), in connection with the financing..., Financings which Constitute Conflicts of Interest, of the Small Business Administration (``SBA'') Rules and... SMALL BUSINESS ADMINISTRATION [License No. 07/07-0117] Eagle Fund III-A, L.P.; Notice Seeking...

DETERMINATION OF LEVEL OF FOOD ADDITIVES IN Labisia pumila (LP) BEVERAGES CONSUMED IN KUANTAN, MALAYSIA

OpenAIRE

Iwansyah, Ade Chandra; Yusoff, Masithah Mohammad; Kormin, Faridah

2013-01-01

The content levels of several food additives (gallic acid, benzoic acid and caffeine) in commercial Labisia pumila (LP) beverage samples in Kuantan, Malaysia were determined by high performances liquid chromatography (HPLC). These analytical measurements were undertaken primarily to assess the compliance of content levels of the investigated food additives and their daily intake doses with permissible levels. The results obtained from this study indicated that the average levels of GA, caffei...

Bedre ældrepleje - ved hjælp af Marte Meo metoden

DEFF Research Database (Denmark)

Meyer, Helle; Schjoldager, Helle Højbo

Projektet (forløb efteråret 2008 - foråret 2009) havde til formål at give personalet ved boformer for borgere med demens indsigt i og redskaber til at kommunikere med borgeren på en for begge parter anerkendende måde - ved hjælp af Marte Meo metoden. Det konkluderes at implementering af Marte Meo...... metoden har medført, at personalet har udviklet deres samspil og kommunikation med borgerne på en måde, der synes at fremme borgerens trivsel, værdighed og livsglæde og dermed bidrage til en øget livskvalitet. En række faktorer der henholdsvis fremmer og hæmmer implementeringen af Marte Meo metoden...

78 FR 57444 - Eagle Fund III, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts...

Science.gov (United States)

2013-09-18

... Small Business Investment Act of 1958, as amended (the ``Act''), in connection with the financing of a... SMALL BUSINESS ADMINISTRATION [License No. 07/07-0116] Eagle Fund III, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle...

LP-LPA: A link influence-based label propagation algorithm for discovering community structures in networks

Science.gov (United States)

Berahmand, Kamal; Bouyer, Asgarali

2018-03-01

Community detection is an essential approach for analyzing the structural and functional properties of complex networks. Although many community detection algorithms have been recently presented, most of them are weak and limited in different ways. Label Propagation Algorithm (LPA) is a well-known and efficient community detection technique which is characterized by the merits of nearly-linear running time and easy implementation. However, LPA has some significant problems such as instability, randomness, and monster community detection. In this paper, an algorithm, namely node’s label influence policy for label propagation algorithm (LP-LPA) was proposed for detecting efficient community structures. LP-LPA measures link strength value for edges and nodes’ label influence value for nodes in a new label propagation strategy with preference on link strength and for initial nodes selection, avoid of random behavior in tiebreak states, and efficient updating order and rule update. These procedures can sort out the randomness issue in an original LPA and stabilize the discovered communities in all runs of the same network. Experiments on synthetic networks and a wide range of real-world social networks indicated that the proposed method achieves significant accuracy and high stability. Indeed, it can obviously solve monster community problem with regard to detecting communities in networks.

Indexing from thesauri to the semantic web

CERN Document Server

de Keyser, Piet

2012-01-01

Indexing consists of both novel and more traditional techniques. Cutting-edge indexing techniques, such as automatic indexing, ontologies, and topic maps, were developed independently of older techniques such as thesauri, but it is now recognized that these older methods also hold expertise. Indexing describes various traditional and novel indexing techniques, giving information professionals and students of library and information sciences a broad and comprehensible introduction to indexing. This title consists of twelve chapters: an Introduction to subject readings and theasauri; Automatic i

Indexes to Nuclear Regulatory Commission Issuances, January--June 1997

International Nuclear Information System (INIS)

1997-01-01

This report indexes the issuances heard and ruled upon from January through June 1997. Issuances are from the Commission, the Atomic Safety and Licensing Boards, the Administrative Law Judges, the Directors' Decisions, and the Decisions on Petitions for Rulemaking. Information provided for each case includes the case name, full test reference, issuance number, issues raised by appellants, legal citations, facility name and docket number, subject matter of issues and/or rulings, type of hearing, and type of issuance. Each issuance is displayed in one or more of five separate formats: (1) case name index, (2) headers and digests, (3) legal citations index, (4) subject index, and (5) facility index

Indexes to Nuclear Regulatory Commission Issuances, January--June 1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-10-01

This report indexes the issuances heard and ruled upon from January through June 1997. Issuances are from the Commission, the Atomic Safety and Licensing Boards, the Administrative Law Judges, the Directors` Decisions, and the Decisions on Petitions for Rulemaking. Information provided for each case includes the case name, full test reference, issuance number, issues raised by appellants, legal citations, facility name and docket number, subject matter of issues and/or rulings, type of hearing, and type of issuance. Each issuance is displayed in one or more of five separate formats: (1) case name index, (2) headers and digests, (3) legal citations index, (4) subject index, and (5) facility index.

Regulatory and technical reports (abstract index journal)

International Nuclear Information System (INIS)

1994-03-01

This compilation consists of bibliographic data and abstracts for the formal regulatory and technical reports issued by the US Nuclear Regulatory Commission staff and its contractors. There are four types of reports included: staff reports, conference reports, contractor reports, and international agreement reports. In addition to the main citations with abstracts, the following are also included: Secondary report number index; Personal author index; Subject index; NRC originating organization indices for staff reports and international agreement reports; NRC contract sponsor index; Contractor index; International organization index; and Licensed facility index

RELAP5/MOD2 post-test calculation of the OECD LOFT experiment LP-SB-2

International Nuclear Information System (INIS)

Perez, J.; Mendizabal, R.

1992-04-01

This document presents the analysis of the OECD LOFT LP-SB-2 Experiment performed by the Consejo de Seguridad Nuclear of Spain working group making use of RELAP5/MOD2 in the frame of the Spanish LOFT Project. LB-SB-2 experiment studies the effect of a delayed pump trip in a small break LOCA scenario with a 3-inch equivalent diameter break in the hot leg of a commercial PWR

77 FR 70429 - Gulf South Pipeline Company, LP; Notice of Intent To Prepare an Environmental Assessment for the...

Science.gov (United States)

2012-11-26

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PF12-21-000] Gulf South Pipeline Company, LP; Notice of Intent To Prepare an Environmental Assessment for the Planned Southeast Market Expansion Project, Request for Comments on Environmental Issues, and Notice of Public Scoping Meetings The staff of the Federal Energy...

76 FR 36914 - Astoria Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas...

Science.gov (United States)

2011-06-23

... Generating Company, L.P., NRG Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas Turbine Power LLC... Power Marketing LLC, Arthur Kill Power LLC, Astoria Gas Turbine Power LLC, Dunkirk Power LLC, Huntley... when a document is added to a subscribed docket(s). For assistance with any FERC Online service, please...

75 FR 45178 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

Science.gov (United States)

2010-08-02

..., Financings which Constitute Conflicts of Interest of the Small Business Administration (``SBA'') Rules and... contemplated to fund the ongoing operating needs of the business. The financing is brought within the purview... SMALL BUSINESS ADMINISTRATION Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption...

Strategic planning for minimizing CO2 emissions using LP model based on forecasted energy demand by PSO Algorithm and ANN

Energy Technology Data Exchange (ETDEWEB)

Yousefi, M.; Omid, M.; Rafiee, Sh. [Department of Agricultural Machinery Engineering, University of Tehran, Karaj (Iran, Islamic Republic of); Ghaderi, S. F. [Department of Industrial Engineering, University of Tehran, Tehran (Iran, Islamic Republic of)

2013-07-01

Iran's primary energy consumption (PEC) was modeled as a linear function of five socioeconomic and meteorological explanatory variables using particle swarm optimization (PSO) and artificial neural networks (ANNs) techniques. Results revealed that ANN outperforms PSO model to predict test data. However, PSO technique is simple and provided us with a closed form expression to forecast PEC. Energy demand was forecasted by PSO and ANN using represented scenario. Finally, adapting about 10% renewable energy revealed that based on the developed linear programming (LP) model under minimum CO2 emissions, Iran will emit about 2520 million metric tons CO2 in 2025. The LP model indicated that maximum possible development of hydropower, geothermal and wind energy resources will satisfy the aim of minimization of CO2 emissions. Therefore, the main strategic policy in order to reduce CO2 emissions would be exploitation of these resources.

Supplement to the Proceedings of the Annual Symposium on Frequency Control (42nd) Held in Baltimore, Maryland on 1-3 June 1988. Subject and Author Index for the Proceedings for the 10th to 42nd Symposia on Frequency Control and Symposium Historical Information, 1946-1988

Science.gov (United States)

1988-01-01

Supplement to the Proceedings of the 42nd Annual Symposium on Frequency Control 1988 Subject and Author Index for the Proceedings of the 10th to 42nd...nsducers . ............................... 71 14/ Other Topics ............................................. 727V" Author / Index ....................................................... 740...John R. Vig, US Army Electronics Technology and Devices Laboratory (LABCOM) This index consists of a subject index and an author index . Each paper

Infimal Convolution Regularisation Functionals of BV and Lp Spaces

KAUST Repository

Burger, Martin

2016-02-03

We study a general class of infimal convolution type regularisation functionals suitable for applications in image processing. These functionals incorporate a combination of the total variation seminorm and Lp norms. A unified well-posedness analysis is presented and a detailed study of the one-dimensional model is performed, by computing exact solutions for the corresponding denoising problem and the case p=2. Furthermore, the dependency of the regularisation properties of this infimal convolution approach to the choice of p is studied. It turns out that in the case p=2 this regulariser is equivalent to the Huber-type variant of total variation regularisation. We provide numerical examples for image decomposition as well as for image denoising. We show that our model is capable of eliminating the staircasing effect, a well-known disadvantage of total variation regularisation. Moreover as p increases we obtain almost piecewise affine reconstructions, leading also to a better preservation of hat-like structures.

Paranormal belief, schizotypy, and Body Mass Index.

Science.gov (United States)

Hergovich, Andreas; Willinger, Ulrike; Arendasy, Martin

2005-06-01

There are indications that subjects with schizotypal personality have a lower Body Mass Index. Also schizotypal personality is linked to a higher incidence of paranormal belief. In this study we examined whether low Body Mass Index is also linked to paranormal belief. In a pilot study 48 students of psychology (85.4% women) between the ages of 20 and 27 years were administered a questionnaire assessing weight, height, and paranormal belief. Analysis suggested an association between belief in paranormal phenomena and low Body Mass Index. In a follow-up study with 300 subjects and equal sex distribution, the relationship was examined under control of schizotypy. The results for Body Mass Index could not be confirmed; however, paranormal belief was heavily associated with the cognitive-perceptual component of schizotypy.

Energy information data base: subject thesaurus

International Nuclear Information System (INIS)

1979-10-01

The technical staff of the DOE Technical Information Center, during its subject indexing activities, develops and structures a vocabulary that allows consistent machine storage and retrieval of information necessary to the accomplishment of the DOE mission. This thesaurus incorporates that structured vocabulary. The terminology of this thesaurus is used for the subject control of information announced in DOE Energy Research Abstracts, Energy Abstracts for Policy Analysis, Solar Energy Update, Geothermal Energy Update, Fossil Energy Update, Fusion Energy Update, and Energy Conservation Update. This terminology also facilitates subject searching of the DOE energy information data base, a research in progress data base, a general and practical energy information data base, power reactor docket information data base, nuclear science abstracts data base, and the federal energy information data base on the DOE on-line retrieval system, RECON. The rapid expansion of the DOE's activities will result in a concomitant thesaurus expansion as information relating to new activities is indexed. Only the terms used in the indexing of documents at the Technical Information Center to date are included

Coronary heart disease index based on longitudinal electrocardiography

Science.gov (United States)

Townsend, J. C.; Cronin, J. P.

1977-01-01

A coronary heart disease index was developed from longitudinal ECG (LCG) tracings to serve as a cardiac health measure in studies of working and, essentially, asymptomatic populations, such as pilots and executives. For a given subject, the index consisted of a composite score based on the presence of LCG aberrations and weighted values previously assigned to them. The index was validated by correlating it with the known presence or absence of CHD as determined by a complete physical examination, including treadmill, resting ECG, and risk factor information. The validating sample consisted of 111 subjects drawn by a stratified-random procedure from 5000 available case histories. The CHD index was found to be significantly more valid as a sole indicator of CHD than the LCG without the use of the index. The index consistently produced higher validity coefficients in identifying CHD than did treadmill testing, resting ECG, or risk factor analysis.

Effect of dissolved oxygen on SCC of LP turbine steel

International Nuclear Information System (INIS)

Maeng, W. Y.; Lee, J. H.; Kim, W. C.

2002-01-01

Slow Strain Rate Tests (SSRT) were carried out to investigate the effect of dissolved oxygen on Stress Corrosion Cracking (SCC) susceptibility of 3.5NiCrMoV steels used in discs of Low-Pressure (LP) steam turbines in electric power generating plants. The influence of dissolved oxygen on cracking in water was studied; for this purpose, specimens were strained to fracture at 150 .deg. C in water environments with various amounts of dissolved oxygen. The maximum elongation of the turbine steel decreased with increasing dissolved oxygen. Dissolved oxygen significantly affected the SCC susceptibility of turbine steel in water. The increase of the SCC susceptibility of the turbine steel in a higher dissolved oxygen environment is due to the non protectiveness of the oxide layer of the turbine steel surface and the increase of corrosion current

76 FR 54758 - Alliance Pipeline L.P.; Notice of Intent To Prepare an Environmental Assessment for the Planned...

Science.gov (United States)

2011-09-02

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PF11-7-000] Alliance Pipeline L.P.; Notice of Intent To Prepare an Environmental Assessment for the Planned Tioga Lateral Project, Request for Comments on Environmental Issues, and Notice of Public Scoping Meeting The staff of the Federal Energy Regulatory Commission (FERC or...

77 FR 13117 - Excelerate Energy L.P.; Notice of Intent To Prepare an Environmental Impact Statement for the...

Science.gov (United States)

2012-03-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PF12-4-000] Excelerate Energy L.P.; Notice of Intent To Prepare an Environmental Impact Statement for the Planned Aguirre Offshore Gasport Project, Request for Comments on Environmental Issues, and Notice of Public Scoping Meetings The staff of the Federal Energy Regulatory...

77 FR 59601 - Dominion Cove Point LNG, LP; Notice of Intent To Prepare an Environmental Assessment for the...

Science.gov (United States)

2012-09-28

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PF12-16-000] Dominion Cove Point LNG, LP; Notice of Intent To Prepare an Environmental Assessment for the Planned Cove Point Liquefaction Project, Request for Comments on Environmental Issues, Notice of On- Site Environmental Review, and Notice of Public Scoping Meetings The...

75 FR 56089 - Equitrans, L.P.; Notice of Intent To Prepare an Environmental Assessment for the Planned Sunrise...

Science.gov (United States)

2010-09-15

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PF10-19-000] Equitrans, L.P.; Notice of Intent To Prepare an Environmental Assessment for the Planned Sunrise Pipeline Project, Request for Comments on Environmental Issues, and Notice of Public Scoping Meeting September 3, 2010. The staff of the Federal Energy Regulatory...

75 FR 56093 - Eagle Rock Desoto Pipeline, LP; Notice of Motion for Extension of Rate Case Filing Deadline

Science.gov (United States)

2010-09-15

... pipelines to extend the cycle for such reviews from three to five years.\\1\\ Therefore, Eagle Rock requests... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR09-1-002] Eagle Rock... notice that on September 8, 2010, Eagle Rock Desoto Pipeline, L.P. (Eagle Rock) filed a request to extend...

The two errors of using the within-subject standard deviation (WSD) as the standard error of a reliable change index.

Science.gov (United States)

Maassen, Gerard H

2010-08-01

In this Journal, Lewis and colleagues introduced a new Reliable Change Index (RCI(WSD)), which incorporated the within-subject standard deviation (WSD) of a repeated measurement design as the standard error. In this note, two opposite errors in using WSD this way are demonstrated. First, being the standard error of measurement of only a single assessment makes WSD too small when practice effects are absent. Then, too many individuals will be designated reliably changed. Second, WSD can grow unlimitedly to the extent that differential practice effects occur. This can even make RCI(WSD) unable to detect any reliable change.

Lidocaine patches reduce pain in trauma patients with rib fractures.

Science.gov (United States)

Zink, Karen A; Mayberry, John C; Peck, Ellen G; Schreiber, Martin A

2011-04-01

Rib fracture pain is notoriously difficult to manage. The lidocaine patch is effective in other pain scenarios with an excellent safety profile. This study assesses the efficacy of lidocaine patches for treating rib fracture pain. A prospectively gathered cohort of patients with rib fracture was retrospectively analyzed for use of lidocaine patches. Patients treated with lidocaine patches were matched to control subjects treated without patches. Subjective pain reports and narcotic use before and after patch placement, or equivalent time points for control subjects, were gathered from the chart. All patients underwent long-term follow-up, including a McGill Pain Questionnaire (MPQ). Twenty-nine patients with lidocaine patches (LP) and 29 matched control subjects (C) were analyzed. During the 24 hours before patch placement, pain scores and narcotic use were similar (LP 5.3, C 4.6, P = 0.19 and LP 51, C 32 mg morphine, P = 0.17). In the 24 hours after patch placement, LP patients had a greater decrease in pain scores (LP 1.2, C 0.0, P = 0.01) with no change in narcotic use (LP -8.4, C 0.5-mg change in morphine, P = 0.25). At 60 days, LP patients had a lower MPQ pain score (LP 7.7, C 12.2, P rib fracture pain. Lidocaine patches resulted in a sustained reduction in pain, outlasting the duration of therapy.

Can body mass index, waist circumference, waist-hip ratio and waist-height ratio predict the presence of multiple metabolic risk factors in Chinese subjects?

Directory of Open Access Journals (Sweden)

Lu Liping

2011-01-01

Full Text Available Abstract Background Obesity is associated with metabolic risk factors. Body mass index (BMI, waist circumference, waist-hip ratio (WHR and waist-height ratio (WHtR are used to predict the risk of obesity related diseases. However, it has not been examined whether these four indicators can detect the clustering of metabolic risk factors in Chinese subjects. Methods There are 772 Chinese subjects in the present study. Metabolic risk factors including high blood pressure, dyslipidemia, and glucose intolerance were identified according to the criteria from WHO. All statistical analyses were performed separately according to sex by using the SPSS 12.0. Results BMI, waist circumference and WHtR values were all significantly associated with blood pressure, glucose, triglyceride and also with the number of metabolic risk factors in both male and female subjects (all of P Conclusion The BMI, waist circumference and WHtR values can similarly predict the presence of multiple metabolic risk factors in Chinese subjects.

Assessment of oxLDL, anti-oxLDL antibodies and lipoprotein-associated phospholipase A2 as cardiovascular risk markers in obese adolescents with and without T1DM

Directory of Open Access Journals (Sweden)

Nesreen N. Omar

2017-12-01

Full Text Available Background: Oxidized low density lipoprotein (oxLDL, anti-oxLDL antibodies (oxLDL Ab and lipoprotein-associated phospholipase A2 (Lp-PLA2 are the sequel of lipoprotein oxidation and were not studied contemporarily in obese adolescents with and without type 1 diabetes (T1DM. Subjects and methods: The current study enrolled seventy-five adolescents with T1DM who were selected as having hyperglycemia and seventy-five matched control subjects. Both the diabetic and the control groups were further divided into obese, normal weight and underweight subgroups according to body mass index (BMI. The following tests were performed: fasting plasma glucose (FG glycated hemoglobin (HbA1c, insulin, apolipoprotein AI (apo AI, apolipoprotein B (apo B, oxLDL, oxLDL Ab and Lp-PLA2 mass. The diabetic subgroups were selected as having hyperglycemia. Results: Obese diabetic subgroup had higher insulin level and HOMA value than underweight and normal weight diabetic subgroups. oxLDL, oxLDL Ab and Lp-PLA2 showed higher concentrations in patients with T1DM than in control subjects (118.48 ± 23.7, 1231.8 ± 940 and 401.26 ± 97.2 vs. 58.1 ± 17.9, 424.9 ± 290.0 and 315.7 ± 70; p < 0.001.. In patients with T1DM, direct correlations were found between oxLDL, oxLDL Ab and Lp-PLA2 and cardiometabolic markers represented by apo B/apo AI ratio, FG and BMI. Conclusion: The current data provide evidence that oxLDL, its retroactive enzyme and antibody are present in circulation early in childhood when primed by obesity and hyperglycemia in T1DM and suggests that they could be useful markers for cardiovascular diseases (CVD. Keywords: OxLDL, OxLDL Ab, Lp-PLA2, Cardiometabolic markers, Obese, Diabetes

18 CFR 341.9 - Index of tariffs.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Index of tariffs. 341.9... SUBJECT TO SECTION 6 OF THE INTERSTATE COMMERCE ACT § 341.9 Index of tariffs. (a) In general. Each carrier must publish as a separate tariff publication under its FERC Tariff numbering system, a complete index...

78 FR 73915 - Solutions Capital I, L.P., License No. 03/03-0247; Notice Seeking Exemption Under Section 312 of...

Science.gov (United States)

2013-12-09

..., Financings which Constitute Conflicts of Interest of the Small Business Administration (``SBA'') Rules and... Business Holdings, Inc., 30775 Barrington, Suite 100, Madison Heights, MI 48071 (``Dorsey''). The financing... SMALL BUSINESS ADMINISTRATION Solutions Capital I, L.P., License No. 03/03-0247; Notice Seeking...

78 FR 2313 - CapitalSpring SBIC, L.P., License No. 09/79-0454, Notice Seeking Exemption Under the Small...

Science.gov (United States)

2013-01-10

... Business Investment Act of 1958, as amended (``the Act''), in connection with the financing of a small... SMALL BUSINESS ADMINISTRATION CapitalSpring SBIC, L.P., License No. 09/79-0454, Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Capital...

76 FR 59767 - Plexus Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment...

Science.gov (United States)

2011-09-27

..., Financings which Constitute Conflicts of Interest of the Small Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). Plexus II, L.P., proposes to provide debt security financing to Project Empire... the Small Business Investment Act of 1958, as amended (``the Act''), in connection with the financing...

Strategic planning for minimizing CO2 emissions using LP model based on forecasted energy demand by PSO Algorithm and ANN

Energy Technology Data Exchange (ETDEWEB)

Yousefi, M.; Omid, M.; Rafiee, Sh. [Department of Agricultural Machinery Engineering, University of Tehran, Karaj (Iran, Islamic Republic of); Ghaderi, S.F. [Department of Industrial Engineering, University of Tehran, Tehran (Iran, Islamic Republic of)

2013-07-01

Iran's primary energy consumption (PEC) was modeled as a linear function of five socioeconomic and meteorological explanatory variables using particle swarm optimization (PSO) and artificial neural networks (ANNs) techniques. Results revealed that ANN outperforms PSO model to predict test data. However, PSO technique is simple and provided us with a closed form expression to forecast PEC. Energy demand was forecasted by PSO and ANN using represented scenario. Finally, adapting about 10% renewable energy revealed that based on the developed linear programming (LP) model under minimum CO2 emissions, Iran will emit about 2520 million metric tons CO2 in 2025. The LP model indicated that maximum possible development of hydropower, geothermal and wind energy resources will satisfy the aim of minimization of CO2 emissions. Therefore, the main strategic policy in order to reduce CO2 emissions would be exploitation of these resources.

Oxidative stress in hepatitis C infected end-stage renal disease subjects.

Science.gov (United States)

Horoz, Mehmet; Bolukbas, Cengiz; Bolukbas, Filiz F; Aslan, Mehmet; Koylu, Ahmet O; Selek, Sahbettin; Erel, Ozcan

2006-07-14

Both uremia and hepatitis C infection is associated with increased oxidative stress. In the present study, we aimed to find out whether hepatitis C infection has any impact on oxidative stress in hemodialysis subjects. Sixteen hepatitis C (+) hemodialysis subjects, 24 hepatitis C negative hemodialysis subjects and 24 healthy subjects were included. Total antioxidant capacity, total peroxide level and oxidative stress index were determined in all subjects. Total antioxidant capacity was significantly higher in controls than hemodialysis subjects with or without hepatitis C infection (all p total peroxide level and oxidative stress index were significantly lower (all p total antioxidant capacity compared to hepatitis C (+) hemodialysis subjects (all p Total peroxide level and oxidative stress index was comparable between hemodialysis subjects with or without hepatitis C infection (p > 0.05/3). Oxidative stress is increased in both hepatitis C (+) and hepatitis C (-) hemodialysis subjects. However, hepatitis C infection seems to not cause any additional increase in oxidative stress in hemodialysis subjects and it may be partly due to protective effect of dialysis treatment on hepatitis C infection.

LOFT/LP-LB-1, Loss of Fluid Test, Large-Break LOCA Experiment

International Nuclear Information System (INIS)

1989-01-01

1 - Description of test facility: The LOFT Integral Test Facility is a scale model of a LPWR. The intent of the facility is to model the nuclear, Thermal-hydraulic phenomena which would take place in a LPWR during a LOCA. The general philosophy in scaling coolant volumes and flow areas in LOFT was to use the ratio of the LOFT core [50 MW(t)] to a typical LPWR core [3000 MW(t)]. For some components, this factor is not applied; however, it is used as extensively as practical. In general, components used in LOFT are similar in design to those of a LPWR. Because of scaling and component design, the LOFT LOCE is expected to closely model a LPWR LOCA. 2 - Description of test: Experiment LP-LB-1 was conducted on 3 February 1984 in the Loss-of-Fluid Test (LOFT) facility at the Idaho National Engineering Laboratory under the auspices of the Organization for Economic Cooperation and Development. The primary objectives of Experiment LP-LB-1 were to determine system transient characteristics and to assess code predictive capabilities for design basis large-break loss-of-coolant accidents in pressurized water reactors (PWRs). This experiment simulated a double-ended offset shear of one inlet pipe in a four-loop PWR and was initiated from conditions representative of licensing limits in a PWR. Other boundary conditions for the simulation were loss of offsite power, rapid primary coolant pump coast down, and United Kingdom minimum safeguard emergency core coolant injection rates. The nuclear fuel rods were not pressurized. The transient was initiated by opening the quick-opening blowdown valves in the broken loop hot and cold legs. 3 - Experimental limitations or shortcomings: Short core and steam generator, excessive core bypass, other scaling compromises, and lack of adequate measurements in certain areas

SUBJECT INDEX

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

granulite belt, India: structural and petrochemical evidences attesting to their relict nature. 337. Earth systems. Earth support systems: Threatened? Why? What can we do? 269. Earthquake source. Earthquake source model using strong motion dis- placement as response of finite elastic media. 9. Eastern Dharwar Craton.

SUBJECT INDEX

Indian Academy of Sciences (India)

ages: Lower Narmada basin, western India. 413. Advective heat transfer. Advective heat transfer and fabric development in a shallow crustal intrusive granite – the case of Pro- terozoic Vellaturu granite, south India. 433. Andaman Islands. Improved bathymetric datasets for the shallow water regions in the Indian Ocean. 261.

SUBJECT INDEX

Indian Academy of Sciences (India)

Northern Central Indian Ridge and their geodynamic implications. 659 ... during winter over a tropical inland station –. Kharagpur .... potential water harvesting sites in the Kali Water- shed, Mahi .... late organic carbon (POC) in the Northeastern Gulf of Mexico. 1 ... Quasi-periodic VLF emissions observed during daytime at a ...

SUBJECT INDEX

Indian Academy of Sciences (India)

Carbon. The influence of Indian Ocean Dipole (IOD) on biogeochemistry of carbon in the Arabian Sea during. 1997–1998. 433 ... Coupled equations for transient water flow, heat flow, ... Penang Island, Malaysia. 661 .... Methane emission.

Subject Index

Indian Academy of Sciences (India)

user1

Multi-Wavelength Studies on H2O Maser Host Galaxies (J. S. Zhang & J. .... N(HI) and Jet Power/Emission in AGNs (Zhongzu Wu, Minfeng Gu & Ming Zhu), 319 .... Emanuela Orrù, David Rafferty, Huub Röttgering, Anna Scaife, Aleksandar ...

SUBJECT INDEX

Indian Academy of Sciences (India)

western India with reference to climate change: Fossil wood evidences. 1373 .... Influence of epicentral distance on local seismic response in Kolkata City, India. 321 .... ture distribution of the deep convective clouds. 1195. Analysis of ...

SUBJECT INDEX

Indian Academy of Sciences (India)

Administrator

2- and 4-mercaptopyridines and their application as corrosion ... ring: Synthesis, structures, stability and utility. 23. Amide ..... HPLC. Isolation and characterization of higher metallo- fullerenes Ca@C92 and Ca@C94. 297 .... m-aminophenol.

SUBJECT INDEX

Indian Academy of Sciences (India)

presence of different types of clouds. 249. Alkaline ... 19. Antarctica. Influence of climatic teleconnections on the temporal ... coastal Dronning Maud Land, East Antarctica. 41 ... On the modeling of electrical boundary layer (elec- trode layer) ...

SUBJECT INDEX

Indian Academy of Sciences (India)

to climate change in the 10 CMIP5 models. 395. Chemical. Influence of nutrient input on the trophic state of a tropical brackish ... Variability of surface ozone with cloud coverage over Kolkata, India ... due to solid earth tides. 603. Investigation ...

SUBJECT INDEX

Indian Academy of Sciences (India)

R.Narasimhan(krishtel emaging)1461 1996 Oct 15 13:05:22

bian Pacific Ocean and its relationship with the wind field using .... Electron spin resonance dating of fault gouge from ... impact. Assimilation of IRS-P4 (MSMR) meteorological data in the NCMRWF global data ... mobile auroral current systems.

SUBJECT INDEX

Indian Academy of Sciences (India)

Unknown

Electrochemical behaviour of alkaline copper complexes. 543 ... Kinetic investigation of the oxidation of N- alkyl anilines by ... Catalytic combustion of methane. A method for increasing ... Cobalt(III), nickel(II) and ruthenium(II) complexes of 1 ...

SUBJECT INDEX

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

alkaline mafic dykes from Swangkre-Rongmil,. East Garo Hills, Shillong plateau, northeast. India. 683. Basalts. Chemical evolution, petrogenesis, and regional chem- ical correlations of the flood basalt sequence in the central Deccan Traps, India.

SUBJECT INDEX

Indian Academy of Sciences (India)

Unknown

Activation energy of viscous flow. Density and viscosity of magnesium sulphate formamide + ethylene glycol mixed solvents ... high average power TEA CO2 laser. 659. Carpaine ... organic sulphides 2,2′-bipyridinium chlo- rochromate. 137.

SUBJECT INDEX

Indian Academy of Sciences (India)

Unknown

dodecyl sulphate (SDS) complex. 299. Acid catalysts ... Synthesis of gold nanoparticles stabilised by metal-chelator and the ... 83. a3Co1+xIr1–xO6. Structural and magnetic anomalies among ..... Direct hydrothermal synthesis of metal inter-.

SUBJECT INDEX

Indian Academy of Sciences (India)

Unknown

Alkylcobaloximes. Equilibria and kinetics of pH-dependent axial ... Bile acid. A new bile acid-derived lariat-ether: Design, synthesis and cation binding properties 607 .... acetone and p-anisidine and their anti- ... Experimental electron density.

SUBJECT INDEX

Indian Academy of Sciences (India)

M. Senthilkumar (Newgen Imaging) 1461 1996 Oct 15 13:05:22

2.5D Simulation of basin-edge effects on the ground ... sity, anomalous resistivity and parallel electric field .... Late Quaternary sea level and environmental ... Energy. Statistical parameters of Bhuj earthquake sequence of January 26th, 2001.

SUBJECT INDEX

Indian Academy of Sciences (India)

Chitosan-based Schiff base-metal complexes (Mn, Cu, Co) as heterogeneous ... Acid concentration dependence ... Adsorption ..... Polymer supported nickel complex: Synthesis, structure ... Eco-friendly kinetic separation of trans-limonene and.

SUBJECT INDEX

Indian Academy of Sciences (India)

Exploring deep potential aquifer in water scarce crystalline ... Behaviour of REEs in a tropical estuary and adjacent continental shelf ... Bengal: Implication for petrogenetic process and tectonic setting. 793 ..... information based approach. 1011.

Subject Index

Indian Academy of Sciences (India)

BetiCiciJoan

Nayak, M. Jamil, L. P. Singh & R. Myrzakulov) 97. Gravitational ... (Solution by the Second Perturbation Method) (Lin-Sen Li) 189. FAST Maser .... γ-Ray Emission from the Extreme Blazar 1ES 0229 + 200 (J. Lie, T. Kang & Y. G.. Zheng) 341 .... C. Eiland, T. C. Salzillo, B. H. Hokr, J. L. Highland, W. D. Mayfield & B. M. Wyatt) ...

SUBJECT INDEX

Indian Academy of Sciences (India)

Unknown

Self-assembly of a Co(II) dimer through H-bonding of water molecules to a 3D ... A density functional theory-based chemical potential equalisation approach to .... Electrochemical determination of hydrogen peroxide using o-dianisidine as ...

Subject Index

Indian Academy of Sciences (India)

user1

Generation of a Near Infra-Red Guide Star Catalog for Thirty-Meter Telescope. Observations (Smitha Subramanian, Annapurni Subramaniam, Luc Simard,. Kim Gillies, A. N. Ramaprakash, G. C. Anupama, C. S. Stalin, Swara. Ravindranath & B. Eswar Reddy), 175. Devasthal Fast Optical Telescope Observations of ...

SUBJECT INDEX

Indian Academy of Sciences (India)

Metal-catalysed organic transformations in water: From bromination to polymerisation ... Sulphur-bridged ruthenium–molybdenum complexes: ..... to ethylene in the presence of CO2 with or without limited O2 ..... Red light laser. Photocleavage ...

SUBJECT INDEX

Indian Academy of Sciences (India)

Selective adsorbent for the extraction and detection of gold(III) 327. Austenitic steel .... Ru3+): catalytic effects for the reduction of 2- or 4-nitroanilines in water. 1651 ...... Leakage current transport mechanisms of La0.67Sr0.33MnO3/.

SUBJECT INDEX

Indian Academy of Sciences (India)

(Afyon-Sandıklı) geothermal systems, SW Turkey 1081. Microtremor measurements ... Analysis of carbon dioxide, water vapour and energy fluxes over an Indian ... Petrological and geochemical characteristics of Paleo- proterozoic ultramafic ...

SUBJECT INDEX

Indian Academy of Sciences (India)

supported on titania catalysts for oxidation reactions 467. 1,2,4-triazoles. Analysis of ... MCM-41 nanocomposites in the gas phase. 989 .... Green oxidation of alkenes in ionic liquid solvent by hydrogen ..... Engineering reactors for catalytic reactions. 341. Catalyst .... Design of non-molecular coordination solids from aqueous ...

SUBJECT INDEX

Indian Academy of Sciences (India)

Great Barrier Reef. Effect of intraband variability on stable isotope and density time series obtained from banded corals. 145. Groundwater. Factors controlling the ... Monsoon depression. Synoptic weather conditions during the pilot study of. Bay of Bengal and Monsoon Experiment (BOBMEX). 211. Nd and Sr isotopes.

Subject Index

Indian Academy of Sciences (India)

Seismic Study of Magnetic Field in the Solar Interior (H. M. Antia), 85 ... Hα Intensity Oscillations in Large Flares (Ram Ajor Maurya & Ashok Ambastha), 249 .... Utilization of GPS Satellites for Precise Irradiation Measurement and Monitoring.

Subject Index

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

Cygnus X-3. X-ray Spectroscopy of Cygnus X-3 (M. Choudhury & A. R. Rao), 39. Eta carinae. High Energy Phenomena in Eta Carinae (R. F. Viotti, L. A. Antonelli, S. Rebecchi &. C. Rossi), 19. Galaxy, active. The Multiwavelength Study of Two Unique Radio Galaxies (N. A. B. Gizani, M. A. Gar- rett & J. P. Leahy), 89. 261 ...

Indexing it all the subject in the age of documentation, information, and data

CERN Document Server

Day, Ronald E

2014-01-01

In this book, Ronald Day offers a critical history of the modern tradition of documentation. Focusing on the documentary index (understood as a mode of social positioning), and drawing on the work of the French documentalist Suzanne Briet, Day explores the understanding and uses of indexicality. He examines the transition as indexes went from being explicit professional structures that mediated users and documents to being implicit infrastructural devices used in everyday information and communication acts. Doing so, he also traces three epistemic eras in the representation of individuals and groups, first in the forms of documents, then information, then data. Day investigates five cases from the modern tradition of documentation. He considers the socio-technical instrumentalism of Paul Otlet, "the father of European documentation" (contrasting it to the hermeneutic perspective of Martin Heidegger); the shift from documentation to information science and the accompanying transformation of persons and texts i...

The Problem of Subject Access to Visual Materials

Directory of Open Access Journals (Sweden)

Heather P. Jespersen

2004-09-01

Full Text Available This article discusses the problem of giving subject access to works of art. We survey both concept-based and content-based access by computers and by indexers/catalogers respectively, as well as issues of interoperability, database and indexer consistency, and cataloging standards. The authors, both of whom are trained art historians, question attempts to mystify fine art subject matter by the creation of clever library science systems that are executed by the naive. Only when trained art historians and knowledgeable catalogers are finally responsible for providing subject access to works of art, will true interoperability and consistency happen.

Estimation of Physiological Cost Index as an Energy Expenditure Index using MacGregor’s Equation

Directory of Open Access Journals (Sweden)

Binaya SJB Rana

2015-09-01

Full Text Available Introduction: Physical activity and energy expenditure can be quantified by measuring heart rate, oxygen uptake and respiratory quotient. The Physiological Cost Index (PCI proposed by MacGregor is a simple and straightforward method to estimate the energy expenditure index. Here, we aim to estimate the energy expenditure among young Asian population using MacGregor’s equation. Methods: A total of 50 young randomly selected healthy females performed 50m, 100m and 150m walking test at their self-selected preferred speed. The physiological cost index values for 100 m walk at speeds slower and faster than the preferred speed were also obtained. The physiological cost index during exercise was calculated using MacGregor’s equation considering heart rate and speed of walking over the varying distances. Results: The PCI values on three different distances are consistent during self selected preferred speed. The PCI estimation on second and third tests for all three distances walked consistently reproducible. However for each distance walked, the first test the PCI was significantly higher than the second and third test values. The PCI values increased significantly when subjects walked either slower (p = 0.02 or faster (p = 0.001 than their normal preferred speed. Conclusion: The physiological cost index values were similar for varying distances walks. The PCI was the least at the preferred speed of walking and increased when the subjects either walked slower or faster than the preferred speed. The first estimation was higher than subsequent estimations. Keywords: energy expenditure index; exercise; physiological cost index. | PubMed

Indexes to Nuclear Regulatory Commission issuances, July-December 1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-05-01

Digests and indexes for issuances of the Commission, the Atomic Safety and Licensing Board Panel, the Administrative Law Judges, the Directors` Decisions, and the Decisions on Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements common to the cases heard and ruled upon are: Case name (owner(s) of facility); Full text reference (volume and pagination); Issuance number Issues raised by appellants; Legal citations (cases, regulations, and statutes); Name of facility, Docket number; Subject matter of issues and/or rulings; Type of hearing (operating license, operating license amendment, etc); Type of issuance (memorandum, order, decision, etc.). These information elements are displayed in one or more of five separate formats: Case Name Index, Headers and Digests, Legal Citations Index, Subject Index, and Facility Index.

Indexes to Nuclear Regulatory Commission issuances, July-December 1997

International Nuclear Information System (INIS)

1998-01-01

Digests and indexes for issuances of the Commission, the Atomic Safety and Licensing Board Panel, the Administrative Law Judges, the Directors' Decisions, and the Decisions on Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements common to the cases heard and ruled upon are: Case name (owner(s) of facility); Full text reference (volume and pagination); Issuance number Issues raised by appellants; Legal citations (cases, regulations, and statutes); Name of facility, Docket number; Subject matter of issues and/or rulings; Type of hearing (operating license, operating license amendment, etc); Type of issuance (memorandum, order, decision, etc.). These information elements are displayed in one or more of five separate formats: Case Name Index, Headers and Digests, Legal Citations Index, Subject Index, and Facility Index

EIA data index: an abstract journal

International Nuclear Information System (INIS)

1980-12-01

The individual tables, graphs, and formatted data presented in the statistical publications of the Energy Information Administration (EIA) are abstracted and indexed. Included are a complete subject index and a report number listing for all EIA publications as well as complete ordering information for these publications. The abstracts of the tables and graphs are arranged by broad subject categories (e.g., coal, petroleum, natural gas, energy analysis and modeling) with further division occurring by subcategories (e.g., reserves, drilling and production, processing). Included here are those publications and their statistical contents which were released by the EIA from its formation in October 1977 through approximately the first half of 1980. Updates will be on a semiannual basis. The EIA Data Index is a companion volume to the EIA Publications Directory: A User's Guide (DOE/EIA-0149), which provides abstracts and indexes to all EIA publications at the document level. Both of these publications are generated from the Federal Energy Data Index (FEDEX) data base which has been developed by the EIA in cooperation with the Technical Information Center of the US Department of Energy

WLPGA: the World LP Gas Association in Berlin; the WLPGA 2004 Action Plan; change of direction; WLPGA: la WLPGA a Berlin; le Plan d'Actions 2004 de la WLPGA; reorientation

Energy Technology Data Exchange (ETDEWEB)

Anon.

2004-07-15

After Bangkok in 2002 and Santiago de Chile in 2003, the World Forum of the World LP Gas Association (WLPGA) is returning to Europe for two and a half days of exhibition and two days of conferences from 29 September to 1 October at the Hotel lnterContinental in Berlin. As a Europe of 25 is now a reality, the Forum will obviously focus on this situation and the prospects for LP Gas in the new group without, however, neglecting the global issues which are why it exists. The WLPGA has a new Managing Director, James Rockall, since 2 August. He previously held the post of Director of Market Development for the Association from july 2003. The 2004 action plan of the World LP Gas Association forms part of the strategic decisions taken at the end of 2001 for the period 2002-2006. Its structure remains identical to that of the previous plan but with the continuous rise in 'the good industrial practices', there is one programme more than in 2003. There is particular emphasis on the programme for developing LP Gas markets in rural areas, at the core of which is the LP Gas Rural Energy Challenge launched 2 years ago in the framework of a partnership with the UNPD. Moreover, the WLPGA contribution to the preparation of the World Energy Outlook of the LEA is testimony to the reinforcement of relations with this agency, and the Association also took part in the World Energy Congress in Sydney. The other programmes are also progressing: GAIN, GLOTEC, without forgetting the preparation of the annual forum and the services provided directly to WLPGA members. Having decided on a change of direction in his career, Emmanuel Chantelot left the WLPGA and the LP Gas industry on 31 July 2004. He should be attending the Members' Dinner at the Berlin Forum. Emmanuel Chantelot has led the World Association for just over 7 years as Managing Director. (authors)

Variations of Lipoprotein(a Levels in the Metabolic Syndrome: A Report from the Maracaibo City Metabolic Syndrome Prevalence Study

Directory of Open Access Journals (Sweden)

Valmore Bermúdez

2013-01-01

Full Text Available Background. Lipoprotein(a [Lp(a] is a known risk factor for cardiovascular disease, yet its influence on metabolic syndrome (MS is still controversial. The purpose of this study was to assess the impact generated by this diagnosis in serum Lp(a concentrations. Materials and Methods. A total of 1807 subjects of both genders (55.3% women and 44.7% men belonging to the Maracaibo City Metabolic Syndrome Prevalence Study were evaluated. Results were expressed as Mean ± SD, determining differences through Student’s t-test and One-Way ANOVA test. Multiple logistic regression models were utilized for analyzing factors associated with elevated serum Lp(a levels and MS. Total cholesterol and LDL-C were corrected according to Lp(a-Cholesterol when necessary. Results. No differences were found in Lp(a values between genders; P=0,292. The association between MS and the classification of Lp(a was statistically significant (χ2=28.33; P<0,0001, with greater levels in subjects with this diagnosis. In the univariate analysis, subjects with each of the separate diagnostic criteria showed higher serum Lp(a concentrations, except for hyperglycemia. Conclusions. Lp(a values exhibit important variations regarding MS and each of its components. Impaired fasting glucose appeared as a protecting factor against elevated Lp(a concentrations, whereas its association with LDL-C and hs-CRP suggests a potential pro-inflammatory role.

Indexes to Volume 75

Indian Academy of Sciences (India)

SUBJECT INDEX. Mathematical .... A 10-Hz terawatt class Ti:sapphire laser system: Development and ... Indigenous development of a 2 kW RF-excited fast axial flow CO2 .... Polarized spectral features of human breast tissues through wavelet.

Plaque Index in Multi-Bracket Fixed Appliances

International Nuclear Information System (INIS)

Rahim, Z.H.; Shaikh, S.; Razak, F.A.

2014-01-01

To compare the plaque index in patients receiving multi-bracket fixed orthodontic treatment for various factors like age, gender, socio-economic status, brushing practices, meal habits, types of brackets, types of ligations, use of mouthwash and duration of treatment. Study Design: Cross-sectional analytical study. Place and Duration of Study: Orthodontics Clinic, The Aga Khan University Hospital, from September to November 2011. Methodology: Socio-demographic and clinical modalities were defined and recorded for 131 patients having multi-bracket fixed appliances. The plaque index of subjects were recorded according to the Silness and Loe plaque index method. Independent sample t-test was used to see difference in plaque index in factors having two variables. One way ANOVA and Post-Hoc Tukey tests were used to see difference in plaque index in factors having three variables. Kappa statistics was used to assess inter examiner reliability. P-value 0.05 was taken to be significant. Results: The sample comprised of 37% males (n = 48) and 63% females (n = 83). The plaque index had statistically significant association with practice of brushing i.e., timing of brushing (p=0.001), method of brushing (p=0.08), type of ligatures (p=0.05) and frequency of visits (p=0.01). Conclusion: The plaque accumulation is significantly decreased in subjects who brush the teeth twice or more than twice a day and those who brush their teeth after breakfast. The use of interdental brush and stainless steel ligatures had significantly low plaque. Subjects presenting with more frequent appointments of short-period had significantly less plaque. (author)

Indexes to Nuclear Regulatory Commission issuances, January--June 1993

International Nuclear Information System (INIS)

1993-11-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements common to the cases heard and ruled upon are: Case name (owner(s) of facility); Full text reference (volume and pagination); Issuance number; Issues raised by appellants; Legal citations (cases, regulations, and statutes); Name of facility, Docket number; Subject matter of issues and/or rulings; Type of hearing (for construction permit, operating license, etc.); Type of issuance (memorandum, order, decision, etc.). These information elements are displayed in one or more of five separate formats arranged as follows: (1) Case Name Index; (2) Digests and Headers; (3) Legal Citations Index; (4) Subject Index; (5) Facility Index

Body mass index is a poor predictor of malnutrition in hospitalized ...

African Journals Online (AJOL)

Objective: Comparison between Subjective Global Assessment and Body Mass Index to determine the nutritional status in patients admitted in an Internal Medicine Service. Methods: Prospective, longitudinal,observational study of a population of 152 patients,using the Subjective Global Assessment and Body Mass Index.

Interpreting weightings of the peer assessment rating index and the discrepancy index across contexts on Chinese patients.

Science.gov (United States)

Liu, Siqi; Oh, Heesoo; Chambers, David William; Xu, Tianmin; Baumrind, Sheldon

2018-04-06

Determine optimal weightings of Peer Assessment Rating (PAR) index and Discrepancy Index (DI) for malocclusion severity assessment in Chinese orthodontic patients. Sixty-nine Chinese orthodontists assessed a full set of pre-treatment records from a stratified random sample of 120 subjects gathered from six university orthodontic centres. Using professional judgment as the outcome variable, multiple regression analyses were performed to derive customized weighting systems for the PAR index and DI, for all subjects and each Angle classification subgroup. Professional judgment was consistent, with an Intraclass Correlation Coefficient (ICC) of 0.995. The PAR index or DI can be reliably measured, with ICC = 0.959 and 0.990, respectively. The predictive accuracy of PAR index was greatly improved by the Chinese weighting process (from r = 0.431 to r = 0.788) with almost equal distribution in each Angle classification subgroup. The Chinese-weighted DI showed a higher predictive accuracy, at P = 0.01, compared with the PAR index (r = 0.851 versus r = 0.788). A better performance was found in the Class II group (r = 0.890) when compared to Class I (r = 0.736) and III (r = 0.785) groups. The Chinese-weighted PAR index and DI were capable of predicting 62 per cent and 73 per cent of total variance in the professional judgment of malocclusion severity in Chinese patients. Differential prediction across Angle classifications merits attention since different weighting formulas were found.

75 FR 12230 - Black Oak Energy, L.L.C., EPIC Merchant Energy, LP, SESCO Enterprises, LLC v. PJM Interconnection...

Science.gov (United States)

2010-03-15

... Energy, L.L.C., EPIC Merchant Energy, LP, SESCO Enterprises, LLC v. PJM Interconnection, L.L.C.; Notice of Filing March 8, 2010. Take notice that on March 1, 2010, PJM Interconnection, L.L.C. filed a..., Order Accepting Compliance filing issued in this proceeding, Black Oak Energy, L.L.C., et al. v. PJM...

77 FR 76586 - GC SBIC IV, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act...

Science.gov (United States)

2012-12-28

... Small Business Investment Act of 1958, as amended (``the Act''), in connection with the financing of two... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0644] GC SBIC IV, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given...

78 FR 69516 - DeltaPoint Capital IV, L.P.; License No. 02/02-0662; Notice Seeking Exemption Under the Small...

Science.gov (United States)

2013-11-19

... Business Investment Act of 1958, as amended (``the Act''), in connection with the financing of a small... SMALL BUSINESS ADMINISTRATION DeltaPoint Capital IV, L.P.; License No. 02/02-0662; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Delta...

Glycaemic index values and physicochemical properties of five brown rice varieties cooked by different domestic cooking methods

Directory of Open Access Journals (Sweden)

Madan Kumar Chapagai

2016-08-01

Full Text Available Background: The prevalence of diabetes has increased dramatically in recent decades in the regions where people excessively consume white rice. Due to higher nutritional values and bioactive components, low to medium glycaemic index (GI brown rice could be a potential alternative to white rice in these regions. Methods: Five varieties, Chiang (CH, Sungyod (SY, Lepnok (LP from Thailand, Long grain specialty 1 (LS 1 and Long grain specialty 2 (LS 2 from Malaysia were tested for GI. Ten test foods were prepared from 5 varieties by 2 cooking techniques (pressure cooker, PC and rice cooker, RC. Overnight fasted 10 healthy subjects were fed with 25 g glucose as a reference food (RF on 3 occasions and amount equivalent to 25 g available carbohydrate portion of test food (TF on 1 occasion in separate days. Fasting and post-prandial capillary blood glucose was measured via finger-prick methods at 0, 15, 30, 45, 60, 90 and 120 min, and the incremental area under curve (iAUC was determined. The GI of each TF was calculated as percentage of incremental area under curve (iAUC of TF over RF. Results: The mean GI values of SY (72 – 81, high, CH and LP (59 – 65, medium and LS 1 and LS 2 (64 – 73, medium to high for cooking were discovered by PC and RC methods. The GI did not vary significantly (p>0.05 among varieties as well as between cooking methods. GI showed a significant negative correlation with the amylose content (r = –0.70, p<0.05 and significant positive correlation with cold peak viscosity (r = 0.80, p<0.01. Conclusions: All five rice varieties irrespectively of the cooking method used are classified as medium to high GI foods. Medium GI varieties could have potential of being used in diabetic diet. Cooking methods did not significantly alter the glycaemic characteristics of the studied varieties. Amylose content and pasting properties can be used for predicting GI of brown rice. It is urgent to explore low GI brown rice varieties in these

Development of safety function assessment trees for pressurized heavy water reactor LP/SD operations

International Nuclear Information System (INIS)

Yang, Hui Chang; Chung, Chang Hyun; Kim, Ki Yong; Jee, Moon Hak; Sung, Chang Kyoung

2003-01-01

The objective of Configuration Risk Management Program(CRMP) is to maintain the safety level by assuring the defense-in-depth of nuclear power plant while the configurations are changed during plant operations, especially for the LP/SD. Such a safety purpose can be achieved by establishing the risk monitoring programs with both quantitative and qualitative features. Generally, the quantitative risk evaluation models, i.e., PRA models are used for the risk evaluation during full power operation, and the qualitative risk evaluation models such as safety function assessment trees are used. Through this study, safety function assessment trees were developed

Indexes to Nuclear Regulatory Commission issuances, January--June 1992

International Nuclear Information System (INIS)

1992-09-01

Digests and indexes for insurances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These information elements are displayed in one or more of five separate formats arranged as follows: Case name index; digests and headers; legal citations index; subject index; and facility index

Indexes to Nuclear Regulatory Commission issuances, January--June 1989

International Nuclear Information System (INIS)

1989-09-01

Digests and indexes for issuances of the Commission, the Atomic Safety and Licensing Appeal Panel, the Atomic Safety and Licensing Board Panel, the Administrative Law Judge, the Directors' Decisions, and the Denials of Petitions of Rulemaking are presented in this document. The information elements are displayed in one or more of five separate formats. These formats are case named index digests and headers, legal citations index, subject index, and facility index

78 FR 32293 - VPC SBIC I, LP, License No. 05/05 0308; Notice Seeking Exemption Under Section 312 of the Small...

Science.gov (United States)

2013-05-29

... the Small Business Investment Act of 1958, as amended (``the Act''), in connection with the financing..., Financings which Constitute Conflicts of Interest of the Small Business Administration (``SBA'') Rules and... SMALL BUSINESS ADMINISTRATION VPC SBIC I, LP, License No. 05/05 0308; Notice Seeking Exemption...

The tell-tale heart: heart rate fluctuations index objective and subjective events during a game of chess.

Science.gov (United States)

Leone, María J; Petroni, Agustín; Fernandez Slezak, Diego; Sigman, Mariano

2012-01-01

During a decision-making process, the body changes. These somatic changes have been related to specific cognitive events and also have been postulated to assist decision-making indexing possible outcomes of different options. We used chess to analyze heart rate (HR) modulations on specific cognitive events. In a chess game, players have a limited time-budget to make about 40 moves (decisions) that can be objectively evaluated and retrospectively assigned to specific subjectively perceived events, such as setting a goal and the process to reach a known goal. We show that HR signals events: it predicts the conception of a plan, the concrete analysis of variations or the likelihood to blunder by fluctuations before to the move, and it reflects reactions, such as a blunder made by the opponent, by fluctuations subsequent to the move. Our data demonstrate that even if HR constitutes a relatively broad marker integrating a myriad of physiological variables, its dynamic is rich enough to reveal relevant episodes of inner thought.

Indexes to Nuclear Regulatory Commission Issuances, January-June 1981

International Nuclear Information System (INIS)

1982-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions of Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements common to the cases heard and ruled upon are: Case name (owners of facility); Full text reference (volume and pagination); Issuance number; Issues raised by appellants; Legal citations (cases, regulations, and statutes); Name of facility, Docket number; Subject matter of issues and/or rulings; Type of hearing (for construction permit, operating license, etc.); and Type of issuance (memorandum, order, decision, etc.). These information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index, Digests and Headers, Legal Citations Index, Subject Index, and Facility Index

Indexes to Nuclear Regulatory Commission Issuances, January--March 1990

International Nuclear Information System (INIS)

1990-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements common to the cases heard and ruled upon are: case name (owner(s) of facility); full text reference (volume and pagination); issuance number; issues raised by appellants; legal citations (cases, regulations, and statutes); name of facility, Docket number; subject matter of issues and/or rulings; type of hearing (for construction permit, operating license, etc.); and type of issuance (memorandum, order, decision, etc.). These information elements are displayed in one or more of five separate formats arranged as follows: case name index; digests and headers; legal citations index; subject index; and facility index

Effect of Obesity on Arch Index in Young Adults

Directory of Open Access Journals (Sweden)

Sneha Sameer Ganu

2013-01-01

Full Text Available Background: Excessive increases in weight bearing forces caused by obesity may negatively affect the lower limbs and feet but minimal research has examined the long-term loading effects of obesity on the musculoskeletal system, particularly in reference to the feet. Objectives: The purpose of the study was to investigate the effect of obesity on medial longitudinal arch of foot in young adults. Method: 60 subjects, 30 obese & 30 non obese were assessed for height & weight using standard technique. Radiographic images under static condition were used for calculating the arch index. Result: The arch index of obese subjects was significantly lower than the non obese subjects & there is a negative correlation between the BMI & the arch index. Conclusion: These results suggests that obesity lowers the medial longitudinal arch of foot.

76 FR 55720 - BB&T Capital Partners Mezzanine Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the...

Science.gov (United States)

2011-09-08

... approval under section 312 of the Act and Section 107.730 (a)(4), Provide Financing to a Small Business to... SMALL BUSINESS ADMINISTRATION [License No. 04/04-0311] BB&T Capital Partners Mezzanine Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of...

Cormic Index Profile of Children with Sickle Cell Anaemia in Lagos, Nigeria

Directory of Open Access Journals (Sweden)

Samuel Olufemi Akodu

2014-01-01

Full Text Available Background. Sickle cell disorders are known to have a negative effect on linear growth. This could potentially affect proportional growth and, hence, Cormic Index. Objective. To determine the Cormic Index in the sickle cell anaemia population in Lagos. Methodology. A consecutive sample of 100 children with haemoglobin genotype SS, aged eight months to 15 years, and 100 age and sex matched controls (haemoglobin genotype AA was studied. Sitting height (upper segment and full length or height were measured. Sitting height was then expressed as a percentage of full length/height (Cormic Index. Results. The mean Cormic Index decreased with age among primary subjects (SS and AA controls. The overall mean Cormic Index among primary subjects was comparable to that of controls (55.0±4.6% versus 54.5±5.2%; 54.8±4.5% versus 53.6±4.9% in boys and girls, respectively. In comparison with AA controls, female children with sickle cell anaemia who were older than 10 years had a significantly lower mean Cormic Index. Conclusion. There was a significant negative relationship between Cormic Index and height in subjects and controls irrespective of gender. Similarly, a significant negative correlation existed between age, sitting height, subischial leg length, weight, and Cormic Index in both subjects and controls.

L p -Dual geominimal surface area

Directory of Open Access Journals (Sweden)

Weidong Wang

2011-01-01

Full Text Available Abstract Lutwak proposed the notion of Lp -geominimal surface area according to the Lp -mixed volume. In this article, associated with the Lp -dual mixed volume, we introduce the Lp -dual geominimal surface area and prove some inequalities for this notion. 2000 Mathematics Subject Classification: 52A20 52A40.

Pattern reversal visual evoked potentials in migraine subjects without aura

Directory of Open Access Journals (Sweden)

Pedro F. Moreira Filho

1994-12-01

Full Text Available Twenty seven patients with migraine without aura were investigated. The age was between 12 and 54 years; 5 were men and 22 women. The diagnosis of migraine was made according to the classification proposed by the International Headache Society. The method of visual evoked potential was performed with pattern reversal (VEP-PR, with monocular stimulation. The stimulation was performed with pattern reversal with 4x4 cm black and white and red and green squared screen placed 1 meter from the nasion at stimulus frequency 1/s; 128 individual trials were analysed. The VEP-PR with black/white and red/green study showed a significant increase of value of the P-100 latency in 10 migraine patients. In 8 cases the LP100 in VEP-PR black/white was normal but in VEP-PR red/green the LP100 showed increase. Specifically in 1 of our cases, LP100 were normal in VEP-PR black/white but in the red/green there were no reproductice waves. On basis of these observations we consider that the method of VEP-PR is an useful instrument for investigation of migraine patients without aura.

Precision Index in the Multivariate Context

Czech Academy of Sciences Publication Activity Database

Šiman, Miroslav

2014-01-01

Roč. 43, č. 2 (2014), s. 377-387 ISSN 0361-0926 R&D Projects: GA MŠk(CZ) 1M06047 Institutional support: RVO:67985556 Keywords : data depth * multivariate quantile * process capability index * precision index * regression quantile Subject RIV: BA - General Mathematics Impact factor: 0.274, year: 2014 http://library.utia.cas.cz/separaty/2014/SI/siman-0425059.pdf

Indexes to Nuclear Regulatory Commission Issuances, July--December 1993

International Nuclear Information System (INIS)

1994-04-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index; Digests and Headers; Legal Citations Index; Subject Index, and Facility Index

Indexes to Nuclear Regulatory Commission issuances, July--September 1993

International Nuclear Information System (INIS)

1994-01-01

Digest and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. these digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case name index; digests and headers; legal citations index; subject index, and facility index

Indexes to Nuclear Regulatory Commission issuances, July--December, 1991

International Nuclear Information System (INIS)

1991-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index; Digests and Headers; Legal Citations Index; Subject Index; and Facility Index

Indexes to Nuclear Regulatory Commission issuances, January--March 1993

International Nuclear Information System (INIS)

1993-07-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case name index; digests and headers; legal citations index; subject index; and facility index

Indexes to Nuclear Regulatory Commission issuances, January--March 1992

International Nuclear Information System (INIS)

1992-06-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case name index; Digests and headers; Legal citations index; subject index; and facility index

Safety analysis report; packages LP-50 tritium package. (Packaging of fissile and other radioactive materials). Final report

International Nuclear Information System (INIS)

Gates, A.A.; McCarthy, P.G.; Edl, J.W.; Chalfant, G.G.

1975-05-01

Elemental tritium is shipped at low pressure in a stainless steel container (LP-50) surrounded by an aluminum vessel and Celotex insulation at least 4 in. thick in a steel drum. The total weight of the package is 260 lbs maximum. The various components that constitute the package are described and are shown in 7 figures. The safety analysis includes: structural evaluations; thermal evaluations; containment; operating procedures; acceptance tests and maintenance program; and design review

75 FR 42436 - Houston Pipe Line Company LP-Bammel Storage, Docket No. PR10-51-000, et. al.; Notice of Baseline...

Science.gov (United States)

2010-07-21

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Houston Pipe Line Company LP--Bammel Storage, Docket No. PR10-51- 000, et. al.; Notice of Baseline Filings July 14, 2010. Houston Pipe Line..., 2010, respectively the applicants listed above submitted their baseline filing of its Statement of...

Seeing the Wood for the Trees: Enhancing Metadata Subject Elements with Weights

Directory of Open Access Journals (Sweden)

Hong Zhang

2011-06-01

Full Text Available Subject indexing has been conducted in a dichotomous way in terms of what the information object is primarily about/of or not, corresponding to the presence or absence of a particular subject term, respectively. With more subject terms brought into information systems via social tagging, manual cataloging, or automated indexing, many more partially relevant results can be retrieved. Using examples from digital image collections and online library catalog systems, we explore the problem and advocate for adding a weighting mechanism to subject indexing and tagging to make web search and navigation more effective and efficient. We argue that the weighting of subject terms is more important than ever in today’s world of growing collections, more federated searching, and expansion of social tagging. Such a weighting mechanism needs to be considered and applied not only by indexers, catalogers, and taggers, but also needs to be incorporated into system functionality and metadata schemas.

ANTHROPOMETRIC STUDY OF NASAL INDEX OF EGYPTIANS

OpenAIRE

Abdelmonem Awad Hegazy

2014-01-01

Background: The nasal index determination is one of the most commonly used anthropometric parameters in classifying human races. There are few reports in medical literature concerning nasal index that specifically address particular Egyptian populations. The objective of this study was to determine the normal parameters of external nose (width, height and nasal index) in Egyptians. Methods: The study was conducted randomly on healthy Egyptian subjects of both sexes. Nasal height and width ...

Computer-assisted indexing for the INIS database

International Nuclear Information System (INIS)

Nevyjel, A.

2006-01-01

INIS has identified computer-assisted indexing as areas where information technology could assist best in maintaining database quality and indexing consistency, while containing production costs. Subject analysis is a very important but also very expensive process in the production of the INIS database. Given the current necessity to process an increased number of records, including subject analysis, without additional staff, INIS as well as the member states need improvements in their processing efficiency. Computer assisted subject analysis is a promising way to achieve this. The quality of the INIS database is defined by its inputting rules. The Thesaurus is a terminological control device used in translating from the natural language of documents, indexers or users into a more constrained system language. It is a controlled and dynamic vocabulary of semantically and generically related terms. It is the essential tool for subject analysis as well as for advanced search engines. To support the identification of descriptors in the free text (title, abstract, free keywords) 'hidden terms' have been introduced as extension of the Thesaurus, which identify phrases or character strings of free text and point to the valid descriptor, which should be suggested. In the process of computer-assisted subject analysis the bibliographic records (including title and abstract) are analyzed by the software, resulting in a list of suggested descriptors. Within the working platform (graphical user interface) the suggested descriptors are sorted by importance (by their relevance for the content of the document) and the subject specialist clearly sees the highlighted context from which the terms were selected. The system allows the subject specialist to accept or reject descriptors from the suggested list and to assign additional descriptors when necessary. First experiences show that a performance enhancement of about 80-100% can be achieved in the subject analysis process. (author)

Lipoprotein(a Serum Levels in Diabetic Patients with Retinopathy

Directory of Open Access Journals (Sweden)

Giulia Malaguarnera

2013-01-01

Full Text Available Background. Atherogenic lipoproteins, such as total cholesterol, LDL cholesterol, oxidized low density lipoprotein, and triglycerides, are associated with progression of retinopathy. Aim. To evaluate the relationship between lipoprotein(a and retinopathy in patients with type 2 diabetes mellitus. Materials and Methods. We enrolled 145 diabetic consecutive patients (82 females, 63 males; mean age 66.8±12 years, mean duration of diabetes 9.4±6.8 years. Presence and severity of retinopathy were evaluated. Serum lipid profile, including Lp(a level, was assessed. Results. High Lp(a levels have been observed in 54 (78.3% subjects and normal levels in 13 (18.85% subjects as regards diabetic patients with retinopathy. Lp(a levels were high in 15 subjects (21.75% and normal in 63 subjects (91.35% as regards patients without retinopathy. Conclusions. Lp(a levels are increased in a significant percentage of patients with retinopathy compared to diabetic patients without retinopathy. The impact of Lp(a levels on diabetic retinopathy needs to be further investigated.

Index of French nuclear literature: IBM 360 programmes for preparing the permuted index of French titles

International Nuclear Information System (INIS)

Chonez, Nicole

1968-12-01

This report contains the assembly list, the flow chart and some comments about each of the IBM 360 assembler language programmes used for preparing one of the subject indexes contained in the bibliographical bulletin entitled: 'Index de la Litterature nucleaire francaise'; this bulletin has been produced by the French C.E.A. since 1968. Only the processing phases from the magnetic tape file of the bibliographical references, assumed correct, to the printing out of the permuted index obtained with the French titles of the documents on the tape are considered here. This permuted index has the peculiarity of automatically regrouping synonyms and certain grammatical variations of the words. (author) [fr

An LP-model to analyse economic and ecological sustainability on Dutch dairy farms: model presentation and application for experimental farm "de Marke"

NARCIS (Netherlands)

Calker, van K.J.; Berentsen, P.B.M.; Boer, de I.J.M.; Giesen, G.W.J.; Huirne, R.B.M.

2004-01-01

Farm level modelling can be used to determine how farm management adjustments and environmental policy affect different sustainability indicators. In this paper indicators were included in a dairy farm LP (linear programming)-model to analyse the effects of environmental policy and management

Indexes to Nuclear Regulatory Commission issuances, July--December 1988

International Nuclear Information System (INIS)

1989-04-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions of Rulemaking are presented in this document. These information elements are displayed in one or more of five separate formats arranged as follows: case name index, digests and headers, legal citations index, subject index, and facility index

Indexes to Nuclear Regulatory Commission issuances, July--September 1988

International Nuclear Information System (INIS)

1989-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions of Rulemaking are presented in this document. These information elements are displayed in one or more of five separate formats. These formats are case name index, digests and headers, legal citations index, subject index and facility index

Indexes to Nuclear Regulatory Commission issuances, July--September 1992

International Nuclear Information System (INIS)

1993-04-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judges (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: 1. Case Name Index: The case name index is an alphabetical arrangement of the case names of the issuances. Each case name is followed by the type of hearing, the type of issuance, docket number, issuance number, and full text reference. 2. Digests and Headers: The headers and digests are presented in issuance number order as follows: the Commission (CLI), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM). The header identifies the issuance by issuance number, case name, facility name, docket number, type of hearing, date of issuance, and type of issuance. 3. Legal Citations Index: This index is divided into four parts and consists of alphabetical or alpha-numerical arrangements of Cases, Regulations, Statutes, and Others. These citations are listed as given in the issuances. Changes in regulations and statutes may have occurred to cause changes in the number or name and/or applicability of the citation. It is therefore important to consider the date of the issuance. 4. Subject Index: Subject words and/or phrases, arranged alphabetically, indicate the issues and subjects covered in the issuances. 5. Facility Index: The index consists of an alphabetical arrangement of facility names from the issuance. The name is followed by docket number, type of hearing, data, type of issuance, issuance number, and full text reference

The Association of Unintentional Changes in Weight, Body Composition, and Homeostasis Model Assessment Index with Glycemic Progression in Non-Diabetic Healthy Subjects

Directory of Open Access Journals (Sweden)

Eun-Jung Rhee

2011-04-01

Full Text Available BackgroundWe performed a retrospective longitudinal study on the effects of changes in weight, body composition, and homeostasis model assessment (HOMA indices on glycemic progression in subjects without diabetes during a four-year follow-up period in a community cohort without intentional intervention.MethodsFrom 28,440 non-diabetic subjects who participated in a medical check-up program in 2004, data on anthropometric and metabolic parameters were obtained after four years in 2008. Body composition analyses were performed with a bioelectrical impedance analyzer. Skeletal muscle index (SMI, % was calculated with lean mass/weight×100. Subjects were divided into three groups according to weight change status in four years: weight loss (≤-5.0%, stable weight (-5.0 to 5.0%, weight gain (≥5.0%. Progressors were defined as the subjects who progressed to impaired fasting glucose or diabetes.ResultsProgressors showed worse baseline metabolic profiles compared with non-progressors. In logistic regression analyses, the increase in changes of HOMA-insulin resistance (HOMA-IR in four years presented higher odds ratios for glycemic progression compared with other changes during that period. Among the components of body composition, a change in waist-hip ratio was the strongest predictor, and SMI change in four years was a significant negative predictor for glycemic progression. Changes in HOMA β-cell function in four years was a negative predictor for glycemic progression.ConclusionIncreased interval changes in HOMA-IR, weight gain and waist-hip ratio was associated with glycemic progression during a four-year period without intentional intervention in non-diabetic Korean subjects.

Indexes to Nuclear Regulatory Commission issuances, July-December 1981

International Nuclear Information System (INIS)

1981-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions of Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: case name index; digests and headers; legal citations index; subject index; and facility index

Indexes to Nuclear Regulatory Commission issuances, January--June 1991

International Nuclear Information System (INIS)

1991-10-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: Case name index, digest and headers, legal citations index, subject index, and facility index

Indexes to Nuclear Regulatory Commission issuances, January--March 1991

International Nuclear Information System (INIS)

1991-06-01

Digests and indexes for Issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: case name index, digests and headers, logical citations index, subject index and facility index

Indexes to Nuclear Regulatory Commission issuances, January-March 1982

International Nuclear Information System (INIS)

1982-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions of Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. This information is displayed in one or more of five separate formats arranged as follows: case name index; digests and headers; legal citations index; subject index; and facility index

Indexes to Nuclear Regulatory Commission issuances, January--June 1990

International Nuclear Information System (INIS)

1990-01-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALI), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: case name index, digests and headers, legal citations index, subject index, and facility index

Indexes to Nuclear Regulatory Commission issuances, July--September 1997

International Nuclear Information System (INIS)

1998-01-01

This digest and index lists the Nuclear Regulatory Commission (NRC) issuances for July to September 1997. Issuances are from the Commission, the Atomic Safety and Licensing Boards, the Administrative Law Judges, the Directors' Decisions, and the Decisions on Petitions for Rulemaking. There are five sections to this index: (1) case name index, (2) headers and digests, (3) legal citations index, (4) subject index, and (5) facility index. The digest provides a brief narrative of the issue, including the resolution of the issue and any legal references used for resolution

Indexes to Nuclear Regulatory Commission issuances, July--September 1990

International Nuclear Information System (INIS)

1990-12-01

Digests and indexes for issuances of the commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. The information elements are displayed in one or more of five separate formats arranged as follows: case name index, digests and headers, legal citations index, subject index, and facility index

Indexes to Nuclear Regulatory Commission issuances, July--December 1990

International Nuclear Information System (INIS)

1991-03-01

Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and Licensing Appeal Panel (ALAB), the Atomic Safety and Licensing Board Panel (LBP), the Administrative Law Judge (ALJ), the Directors' Decisions (DD), and the Denials of Petitions for Rulemaking are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. These information elements are displayed in one or more of five separate formats arranged as follows: case name index, digests and headers legal citations index, subject index, and facility index

The Healthy Lifestyles Programme (HeLP)--an overview of and recommendations arising from the conceptualisation and development of an innovative approach to promoting healthy lifestyles for children and their families.

Science.gov (United States)

Lloyd, Jenny; Wyatt, Katrina

2015-01-20

Despite the rise in childhood obesity, there remains a paucity of evidence for effective interventions that engage children and parents sufficiently to make and sustain lifestyle behaviour change. The Healthy Lifestyles Programme (HeLP) is a school-located obesity prevention programme, which has been developed with teachers, families and healthcare professionals. The underpinning assumption in the development of HeLP was to take a relational approach to changing behaviour, building relationships with the schools, children and their families to create supportive environments for healthy lifestyle choices. Thus, HeLP was conceptualised as a complex intervention within a complex system and developed as a dynamic, evolving set of processes to support and motivate children towards healthy behaviours. The delivery methods used are highly interactive and encourage identification with and ownership of the healthy lifestyle messages so that the children are motivated to take them home to their parents and effect change within the family. We have good evidence that HeLP engages schools and children such that they want to participate in the Programme. Results from an exploratory trial showed that the Programme is feasible and acceptable and has the potential to change behaviours and affect weight status. This paper presents an overview of and recommendations arising from the conceptualization; development and evaluation of the Healthy Lifestyles Programme as part of a special issue focusing on novel approaches to the global problem of childhood obesity.

Glycaemic index of different coconut (Cocos nucifera)-flour products in normal and diabetic subjects.

Science.gov (United States)

Trinidad, Trinidad P; Valdez, Divinagracia H; Loyola, Anacleta S; Mallillin, Aida C; Askali, Faridah C; Castillo, Joan C; Masa, Dina B

2003-09-01

The glycaemic index (GI) of commonly consumed bakery products supplemented with increasing levels of coconut (Cocos nucifera) flour was determined in ten normal and ten diabetic subjects. Using a randomized crossover design, the control and test foods were fed in random order on separate occasions after an overnight fast. Blood samples were collected through finger prick before and after feeding and were analysed for glucose levels using a clinical chemistry analyser. The significantly low-GI (cake (GI 51.8 (sem 3.3)), with 200-250 g coconut flour/kg (Pflour/kg had GI ranging from 61.3 to 71.4. Among the test foods, pan de sal (GI 87.2 (sem 5.5)) and multigrain loaf (GI 85.2 (sem 6.8)) gave significantly higher GI with 50 and 100 g coconut flour/kg respectively (Pflour/kg respectively gave a GI ranging from 62.7 to 71.6 and did not differ significantly from the test foods with 150 g coconut flour/kg (Pflour. In conclusion, the GI of coconut flour-supplemented foods decreased with increasing levels of coconut flour and this may be due to its high dietary fibre content. The results of the present study may form a scientific basis for the development of coconut flour as a functional food. However, the fat content of coconut flour-supplemented food should always be considered to optimize the functionality of coconut fibre in the proper control and management of diabetes mellitus.

KWIC Index to Government Publications

Directory of Open Access Journals (Sweden)

Margaret Norden

2013-05-01

Full Text Available United States and United Nations publications were not efficiently proc- essed nor readily available to the reader at Brandeis University Library. Data processing equipment was used to make a list of this material which could be referred to by a computer produced KWIC index. Currency and availability to the user, and time and cost efficiencies for the library were given precedence over detailed subject access. United States and United Nations classification schemes> and existing bibliographies and indexes were used extensively.

Gradient-Index Optics

Science.gov (United States)

2010-03-31

nonimaging design capabilities to incorporate 1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND SUBTITLE 12-04-2011 13. SUPPLEMENTARY NOTES The views, opinions...Box 12211 Research Triangle Park, NC 27709-2211 15. SUBJECT TERMS Imaging Optics, Nonimaging Optics, Gradient Index Optics, Camera, Concentrator...imaging and nonimaging design capabilities to incorporate manufacturable GRIN lenses can provide imaging lens systems that are compact and

INDEXABILITY AND OPTIMAL INDEX POLICIES FOR A CLASS OF REINITIALISING RESTLESS BANDITS.

Science.gov (United States)

Villar, Sofía S

2016-01-01

Motivated by a class of Partially Observable Markov Decision Processes with application in surveillance systems in which a set of imperfectly observed state processes is to be inferred from a subset of available observations through a Bayesian approach, we formulate and analyze a special family of multi-armed restless bandit problems. We consider the problem of finding an optimal policy for observing the processes that maximizes the total expected net rewards over an infinite time horizon subject to the resource availability. From the Lagrangian relaxation of the original problem, an index policy can be derived, as long as the existence of the Whittle index is ensured. We demonstrate that such a class of reinitializing bandits in which the projects' state deteriorates while active and resets to its initial state when passive until its completion possesses the structural property of indexability and we further show how to compute the index in closed form. In general, the Whittle index rule for restless bandit problems does not achieve optimality. However, we show that the proposed Whittle index rule is optimal for the problem under study in the case of stochastically heterogenous arms under the expected total criterion, and it is further recovered by a simple tractable rule referred to as the 1-limited Round Robin rule. Moreover, we illustrate the significant suboptimality of other widely used heuristic: the Myopic index rule, by computing in closed form its suboptimality gap. We present numerical studies which illustrate for the more general instances the performance advantages of the Whittle index rule over other simple heuristics.

Indexes to Nuclear Regulatory Commission Issuances, January 1996--June 1996

International Nuclear Information System (INIS)

1996-09-01

Digests and indexes for issuances of the Commission, the Atomic Safety and Licensing Board Panel, The Administrative Law Judges, the Director's Decisions, and the Decisions on Petitions for Rulemaking are presented in this document. The digests and indexes are intended to serve as a guide to the issuances. Information elements common the cases hear and ruled upon are displayed in one or more of five formats: case name index, headers and digests, legal citations index, subject index, and facility index

Indexes to Nuclear Regulatory Commission Issuances, January 1996--June 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-09-01

Digests and indexes for issuances of the Commission, the Atomic Safety and Licensing Board Panel, The Administrative Law Judges, the Director`s Decisions, and the Decisions on Petitions for Rulemaking are presented in this document. The digests and indexes are intended to serve as a guide to the issuances. Information elements common the cases hear and ruled upon are displayed in one or more of five formats: case name index, headers and digests, legal citations index, subject index, and facility index.

Relationship of visfatin level to pancreatic endocrine hormone level, HOMA-IR index, and HOMA β-cell index in overweight women who performed hydraulic resistance exercise.

Science.gov (United States)

Ha, Chang Ho; Swearingin, Brenda; Jeon, Yong Kyun

2015-09-01

[Purpose] This study aimed to examine the correlation of visfatin level to pancreatic endocrine hormone level, homeostasis model assessment of insulin resistance (HOMA-IR) index, and HOMA β-cell index in hydraulic resistance exercise. Furthermore, it investigated the relationship between visfatin level and other variables affected by exercise in overweight women. [Subjects and Methods] The exercise group trained for 12 weeks, 70 minutes/day, 5 days/week. Visfatin level, pancreatic endocrine hormone level, HOMA-IR index, and HOMA β-cell index were measured before and after the intervention. Based on the blood insulin and glucose concentrations, HOMA-IR index, the indicator of insulin resistance, and HOMA β-cell index, the indicator of insulin secretion level, were assessed. [Results] Interaction effects on visfatin level, insulin level, HOMA-IR index, and HOMA β-cell index were observed. Interaction effects on glucagon and glucose levels were not observed between the intervention groups. The correlations of visfatin level to insulin, glucagon, and glucose levels, and HOMA-IR and HOMA β-cell indexes were not significant for any of the subjects. [Conclusion] Therefore, the 12-week resistance exercise affected body composition, visfatin level, insulin level, HOMA-IR index, and HOMA β-cell index. Finally, visfatin was not related to insulin, glucagon, and glucose levels, and HOMA-IR and HOMA β-cell indexes.

Progade PT path, prograde fluid flow, metasomatism and hydrous melting in the Osor high-grade HT-LP complex (Catalan Coastal Ranges-CCR, NE Iberia).

Science.gov (United States)

Reche, Joan; Martínez, Francisco; Leoz, Gisela

2015-04-01

Fast thermal pulses related to HT-LP metamorphism may imply dehydration reaction overstepping, higher than normal fluid production rates, quick local increases in Pfluid and common situations of Pfluid >> Plitostatic and surpassing locally the tensile stresses. This ambient would be favorable to transient hydrofracturing and fluid flow even if the ongoing HT-LP event develops on dominantly ductile crustal levels. In inner zones where temperatures are high enough, hydrous melting and melt migration would be favored as well. Such movement of fluids and melts would tend to be sustained if non-hydrostatic stresses are active during heating, and would be favored in high strain domains such high-T shear zones or along foliation planes. In such scenario, local metasomatic processes and mass-transfer phenomena are expected to occur along these high strain zones and so distributed along tectonic anisotropies. A variety of features found in high T Garnet - biotite-sillimanite±cordierite±plagioclase±K-feldspar±quartz metapelitic gneisses from the Osor Complex (Guilleries massif, CCR), testify from this kind of processes operating in the lower crustal section, at the amphibolite to granulite transition zone during a prograde Variscan HT-LP thermal pulse. Such features include: syn-D2 quartz veining, leucogranitoid (leucotonalite, trondhjemitic) lenses sub parallel to S2 dominant foliation, fibrolite-rich foliation planes and prograde sub-idiomorphic garnet developing preferentially near fluid migration channels (quartz veins) or near melt lenses.

Study on the transfer factor of plant available form of zinc

International Nuclear Information System (INIS)

Ohmomo, Yoichiro; Uchida, Shigeo; Yokosuka, Setsuko; Honma, Yoshifumi

1989-01-01

Method for the determination of labile pool Zn (Lp Zn), which was presented by Lauer, was examined to adapt it for that of another labile pool element (Lp E). It was suggested that the Lp E should be more accurately obtained by correcting error due to aging of the relevant radioisotope added to soil. A modified equation is given as following; Lp E = (net Lp * E)/(specific activity in extract) The net Lp * E is calculated as product after subtracting radioactivity not extracted by 0.1 M HCl from that initially added to soil. It was also suggested that substantial extracting reagent and conditions, by which nearly whole quantity of an element in labile pool was extracted, could be found out using thus obtained Lp E as an index. Transfer coefficients and those based on plant available form of Zn were experimentally obtained for several kinds of crops. (author)

[Effects of Two Placement Ways for Storage of Blood Bag on Biochemical Indexes of Leukodepleted Red Blood Cells].

Science.gov (United States)

Zhang, Rui-Jun; Duan, Bing-Zheng; Ju, Chun-Mei; Sui, Su-Qin; Bai, Yan; Cao, Huan

2016-04-01

To investigate the effects of 2 different ways of storage bag placement on some biochemical indexes of leukodepleted red blood cells (LD-RBC) to as to ensure the efficacy and safety of clinical blood transfusion. The whole blood samples of 20 donors (400 ml/donor) were selected for preparating the LP-RBC, which were divided evenly into 10 bags. The 10 bags were randomly divided into 2 groups; the bags in 1 group were placed uprightly, while the bags in another group were placed horizontally. The bags of 2 groups were stored in the same conditions. One storage bag from each group was taken randomly on day 7, 14, 21, 28, 35 respectively, and then the biochemical indexes of samples were detected and analyzed. The values of K(+) and LAC on day 14, the value of LDH on day 28 in the uprightly placed group were higher than those in the horizontally placed group (P value of Na(+) on day 28, and the value of Glu on day 35 in the uprightly placed group were lower than those in horizontally placed group (P 0.05). The storage bags placed by different ways during the storage show different influence on some biochemical indexes of LD-RBC in the storage period.

The Healthy Lifestyles Programme (HeLP — An Overview of and Recommendations Arising from the Conceptualisation and Development of an Innovative Approach to Promoting Healthy Lifestyles for Children and Their Families

Directory of Open Access Journals (Sweden)

Jenny Lloyd

2015-01-01

Full Text Available Despite the rise in childhood obesity, there remains a paucity of evidence for effective interventions that engage children and parents sufficiently to make and sustain lifestyle behaviour change. The Healthy Lifestyles Programme (HeLP is a school-located obesity prevention programme, which has been developed with teachers, families and healthcare professionals. The underpinning assumption in the development of HeLP was to take a relational approach to changing behaviour, building relationships with the schools, children and their families to create supportive environments for healthy lifestyle choices. Thus, HeLP was conceptualised as a complex intervention within a complex system and developed as a dynamic, evolving set of processes to support and motivate children towards healthy behaviours. The delivery methods used are highly interactive and encourage identification with and ownership of the healthy lifestyle messages so that the children are motivated to take them home to their parents and effect change within the family. We have good evidence that HeLP engages schools and children such that they want to participate in the Programme. Results from an exploratory trial showed that the Programme is feasible and acceptable and has the potential to change behaviours and affect weight status. This paper presents an overview of and recommendations arising from the conceptualization; development and evaluation of the Healthy Lifestyles Programme as part of a special issue focusing on novel approaches to the global problem of childhood obesity.

Association between investigator-measured body-mass index and colorectal adenoma: a systematic review and meta-analysis of 168,201 subjects.

Science.gov (United States)

Wong, Martin Chi-Sang; Chan, Chun-Hei; Cheung, Wilson; Fung, Din-Hei; Liang, Miaoyin; Huang, Jason Li-Wen; Wang, Yan-Hong; Jiang, Johnny Yu; Yu, Chun-Pong; Wang, Harry Haoxiang; Wu, Justin Che-Yuen; Chan, Francis Ka-Leung; Sung, Joseph Jao-Yiu

2018-01-01

The objective of this meta-analysis is to evaluate the odds of colorectal adenoma (CRA) in colorectal cancer screening participants with different body mass index (BMI) levels, and examine if this association was different according to gender and ethnicity. The EMBASE and MEDLINE were searched to enroll high quality observational studies that examined the association between investigator-measured BMI and colonoscopy-diagnosed CRA. Data were independently extracted by two reviewers. A random-effects meta-analysis was conducted to estimate the summary odds ratio (SOR) for the association between BMI and CRA. The Cochran's Q statistic and I 2 analyses were used to assess the heterogeneity. A total of 17 studies (168,201 subjects) were included. When compared with subjects having BMI CRA (SOR 1.44, 95% CI 1.30-1.61; I 2  = 43.0%). Subjects with BMI ≥ 30 had similarly higher risk of CRA (SOR 1.42, 95% CI 1.24-1.63; I 2  = 18.5%). The heterogeneity was mild to moderate among studies. The associations were significantly higher than estimates by previous meta-analyses. There was no publication bias detected (Egger's regression test, p = 0.584). Subgroup analysis showed that the magnitude of association was significantly higher in female than male subjects (SOR 1.43, 95% CI 1.30-1.58 vs. SOR 1.16, 95% CI 1.07-1.24; different among different ethnic groups (SOR 1.72, 1.44 and 0.88 in White, Asians and Africans, respectively) being insignificant in Africans; and no difference exists among different study designs. In summary, the risk conferred by BMI for CRA was significantly higher than that reported previously. These findings bear implications in CRA risk estimation.

The role of natural organic matter in nitrite formation by LP-UV/H2O2 treatment of nitrate-rich water.