Sample records for subgrid-scale landscape discontinuities

  1. Sub-grid scale models for discontinuous Galerkin methods based on the Mori-Zwanzig formalism (United States)

    Parish, Eric; Duraisamy, Karthk


    The optimal prediction framework of Chorin et al., which is a reformulation of the Mori-Zwanzig (M-Z) formalism of non-equilibrium statistical mechanics, provides a framework for the development of mathematically-derived closure models. The M-Z formalism provides a methodology to reformulate a high-dimensional Markovian dynamical system as a lower-dimensional, non-Markovian (non-local) system. In this lower-dimensional system, the effects of the unresolved scales on the resolved scales are non-local and appear as a convolution integral. The non-Markovian system is an exact statement of the original dynamics and is used as a starting point for model development. In this work, we investigate the development of M-Z-based closures model within the context of the Variational Multiscale Method (VMS). The method relies on a decomposition of the solution space into two orthogonal subspaces. The impact of the unresolved subspace on the resolved subspace is shown to be non-local in time and is modeled through the M-Z-formalism. The models are applied to hierarchical discontinuous Galerkin discretizations. Commonalities between the M-Z closures and conventional flux schemes are explored. This work was supported in part by AFOSR under the project ''LES Modeling of Non-local effects using Statistical Coarse-graining'' with Dr. Jean-Luc Cambier as the technical monitor.

  2. Sub-Grid Scale Plume Modeling

    Directory of Open Access Journals (Sweden)

    Greg Yarwood


    Full Text Available Multi-pollutant chemical transport models (CTMs are being routinely used to predict the impacts of emission controls on the concentrations and deposition of primary and secondary pollutants. While these models have a fairly comprehensive treatment of the governing atmospheric processes, they are unable to correctly represent processes that occur at very fine scales, such as the near-source transport and chemistry of emissions from elevated point sources, because of their relatively coarse horizontal resolution. Several different approaches have been used to address this limitation, such as using fine grids, adaptive grids, hybrid modeling, or an embedded sub-grid scale plume model, i.e., plume-in-grid (PinG modeling. In this paper, we first discuss the relative merits of these various approaches used to resolve sub-grid scale effects in grid models, and then focus on PinG modeling which has been very effective in addressing the problems listed above. We start with a history and review of PinG modeling from its initial applications for ozone modeling in the Urban Airshed Model (UAM in the early 1980s using a relatively simple plume model, to more sophisticated and state-of-the-science plume models, that include a full treatment of gas-phase, aerosol, and cloud chemistry, embedded in contemporary models such as CMAQ, CAMx, and WRF-Chem. We present examples of some typical results from PinG modeling for a variety of applications, discuss the implications of PinG on model predictions of source attribution, and discuss possible future developments and applications for PinG modeling.

  3. Simple subgrid scale stresses models for homogeneous isotropic turbulence (United States)

    Aupoix, B.; Cousteix, J.

    Large eddy simulations employing the filtering of Navier-Stokes equations highlight stresses, related to the interaction between large scales below the cut and small scales above it, which have been designated 'subgrid scale stresses'. Their effects include both the energy flux through the cut and a component of viscous diffusion. The eddy viscosity introduced in the subgrid scale models which give the correct energy flux through the cut by comparison with spectral closures is shown to depend only on the small scales. The Smagorinsky (1963) model can only be obtained if the cut lies in the middle of the inertial range. A novel model which takes the small scales into account statistically, and includes the effects of viscosity, is proposed and compared with classical models for the Comte-Bellot and Corrsin (1971) experiment.

  4. Statistical dynamical subgrid-scale parameterizations for geophysical flows

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    O' Kane, T J; Frederiksen, J S [Centre for Australian Weather and Climate Research, Bureau of Meteorology, 700 Collins St, Docklands, Melbourne, VIC (Australia) and CSIRO Marine and Atmospheric Research, Aspendale, VIC (Australia)], E-mail:


    Simulations of both atmospheric and oceanic circulations at given finite resolutions are strongly dependent on the form and strengths of the dynamical subgrid-scale parameterizations (SSPs) and in particular are sensitive to subgrid-scale transient eddies interacting with the retained scale topography and the mean flow. In this paper, we present numerical results for SSPs of the eddy-topographic force, stochastic backscatter, eddy viscosity and eddy-mean field interaction using an inhomogeneous statistical turbulence model based on a quasi-diagonal direct interaction approximation (QDIA). Although the theoretical description on which our model is based is for general barotropic flows, we specifically focus on global atmospheric flows where large-scale Rossby waves are present. We compare and contrast the closure-based results with an important earlier heuristic SSP of the eddy-topographic force, based on maximum entropy or statistical canonical equilibrium arguments, developed specifically for general ocean circulation models (Holloway 1992 J. Phys. Oceanogr. 22 1033-46). Our results demonstrate that where strong zonal flows and Rossby waves are present, such as in the atmosphere, maximum entropy arguments are insufficient to accurately parameterize the subgrid contributions due to eddy-eddy, eddy-topographic and eddy-mean field interactions. We contrast our atmospheric results with findings for the oceans. Our study identifies subgrid-scale interactions that are currently not parameterized in numerical atmospheric climate models, which may lead to systematic defects in the simulated circulations.

  5. Modeling Subgrid Scale Droplet Deposition in Multiphase-CFD (United States)

    Agostinelli, Giulia; Baglietto, Emilio


    The development of first-principle-based constitutive equations for the Eulerian-Eulerian CFD modeling of annular flow is a major priority to extend the applicability of multiphase CFD (M-CFD) across all two-phase flow regimes. Two key mechanisms need to be incorporated in the M-CFD framework, the entrainment of droplets from the liquid film, and their deposition. Here we focus first on the aspect of deposition leveraging a separate effects approach. Current two-field methods in M-CFD do not include appropriate local closures to describe the deposition of droplets in annular flow conditions. As many integral correlations for deposition have been proposed for lumped parameters methods applications, few attempts exist in literature to extend their applicability to CFD simulations. The integral nature of the approach limits its applicability to fully developed flow conditions, without geometrical or flow variations, therefore negating the scope of CFD application. A new approach is proposed here that leverages local quantities to predict the subgrid-scale deposition rate. The methodology is first tested into a three-field approach CFD model.

  6. Subgrid-scale turbulence in shock-boundary layer flows (United States)

    Jammalamadaka, Avinash; Jaberi, Farhad


    Data generated by direct numerical simulation (DNS) for a Mach 2.75 zero-pressure gradient turbulent boundary layer interacting with shocks of different intensities are used for a priori analysis of subgrid-scale (SGS) turbulence and various terms in the compressible filtered Navier-Stokes equations. The numerical method used for DNS is based on a hybrid scheme that uses a non-dissipative central scheme in the shock-free turbulent regions and a robust monotonicity-preserving scheme in the shock regions. The behavior of SGS stresses and their components, namely Leonard, Cross and Reynolds components, is examined in various regions of the flow for different shock intensities and filter widths. The backscatter in various regions of the flow is found to be significant only instantaneously, while the ensemble-averaged statistics indicate no significant backscatter. The budgets for the SGS kinetic energy equation are examined for a better understanding of shock-tubulence interactions at the subgrid level and also with the aim of providing useful information for one-equation LES models. A term-by-term analysis of SGS terms in the filtered total energy equation indicate that while each term in this equation is significant by itself, the net contribution by all of them is relatively small. This observation is consistent with our a posteriori analysis.

  7. A priori study of subgrid-scale flux of a passive scalar in isotropic homogeneous turbulence

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    Chumakov, Sergei [Los Alamos National Laboratory


    We perform a direct numerical simulation (DNS) of forced homogeneous isotropic turbulence with a passive scalar that is forced by mean gradient. The DNS data are used to study the properties of subgrid-scale flux of a passive scalar in the framework of large eddy simulation (LES), such as alignment trends between the flux, resolved, and subgrid-scale flow structures. It is shown that the direction of the flux is strongly coupled with the subgrid-scale stress axes rather than the resolved flow quantities such as strain, vorticity, or scalar gradient. We derive an approximate transport equation for the subgrid-scale flux of a scalar and look at the relative importance of the terms in the transport equation. A particular form of LES tensor-viscosity model for the scalar flux is investigated, which includes the subgrid-scale stress. Effect of different models for the subgrid-scale stress on the model for the subgrid-scale flux is studied.

  8. The subgrid-scale scalar variance under supercritical pressure conditions (United States)

    Masi, Enrica; Bellan, Josette


    To model the subgrid-scale (SGS) scalar variance under supercritical-pressure conditions, an equation is first derived for it. This equation is considerably more complex than its equivalent for atmospheric-pressure conditions. Using a previously created direct numerical simulation (DNS) database of transitional states obtained for binary-species systems in the context of temporal mixing layers, the activity of terms in this equation is evaluated, and it is found that some of these new terms have magnitude comparable to that of governing terms in the classical equation. Most prominent among these new terms are those expressing the variation of diffusivity with thermodynamic variables and Soret terms having dissipative effects. Since models are not available for these new terms that would enable solving the SGS scalar variance equation, the adopted strategy is to directly model the SGS scalar variance. Two models are investigated for this quantity, both developed in the context of compressible flows. The first one is based on an approximate deconvolution approach and the second one is a gradient-like model which relies on a dynamic procedure using the Leonard term expansion. Both models are successful in reproducing the SGS scalar variance extracted from the filtered DNS database, and moreover, when used in the framework of a probability density function (PDF) approach in conjunction with the β-PDF, they excellently reproduce a filtered quantity which is a function of the scalar. For the dynamic model, the proportionality coefficient spans a small range of values through the layer cross-stream coordinate, boding well for the stability of large eddy simulations using this model.

  9. Physical consistency of subgrid-scale models for large-eddy simulation of incompressible turbulent flows

    CERN Document Server

    Silvis, Maurits H; Verstappen, Roel


    We study the construction of subgrid-scale models for large-eddy simulation of incompressible turbulent flows. In particular, we aim to consolidate a systematic approach of constructing subgrid-scale models, based on the idea that it is desirable that subgrid-scale models are consistent with the properties of the Navier-Stokes equations and the turbulent stresses. To that end, we first discuss in detail the symmetries of the Navier-Stokes equations, and the near-wall scaling behavior, realizability and dissipation properties of the turbulent stresses. We furthermore summarize the requirements that subgrid-scale models have to satisfy in order to preserve these important mathematical and physical properties. In this fashion, a framework of model constraints arises that we apply to analyze the behavior of a number of existing subgrid-scale models that are based on the local velocity gradient. We show that these subgrid-scale models do not satisfy all the desired properties, after which we explain that this is p...

  10. Evapotranspiration and cloud variability at regional sub-grid scales (United States)

    Vila-Guerau de Arellano, Jordi; Sikma, Martin; Pedruzo-Bagazgoitia, Xabier; van Heerwaarden, Chiel; Hartogensis, Oscar; Ouwersloot, Huug


    In regional and global models uncertainties arise due to our incomplete understanding of the coupling between biochemical and physical processes. Representing their impact depends on our ability to calculate these processes using physically sound parameterizations, since they are unresolved at scales smaller than the grid size. More specifically over land, the coupling between evapotranspiration, turbulent transport of heat and moisture, and clouds lacks a combined representation to take these sub-grid scales interactions into account. Our approach is based on understanding how radiation, surface exchange, turbulent transport and moist convection are interacting from the leaf- to the cloud scale. We therefore place special emphasis on plant stomatal aperture as the main regulator of CO2-assimilation and water transpiration, a key source of moisture source to the atmosphere. Plant functionality is critically modulated by interactions with atmospheric conditions occurring at very short spatiotemporal scales such as cloud radiation perturbations or water vapour turbulent fluctuations. By explicitly resolving these processes, the LES (large-eddy simulation) technique is enabling us to characterize and better understand the interactions between canopies and the local atmosphere. This includes the adaption time of vegetation to rapid changes in atmospheric conditions driven by turbulence or the presence of cumulus clouds. Our LES experiments are based on explicitly coupling the diurnal atmospheric dynamics to a plant physiology model. Our general hypothesis is that different partitioning of direct and diffuse radiation leads to different responses of the vegetation. As a result there are changes in the water use efficiencies and shifts in the partitioning of sensible and latent heat fluxes under the presence of clouds. Our presentation is as follows. First, we discuss the ability of LES to reproduce the surface energy balance including photosynthesis and CO2 soil respiration coupled to the dynamics of a convective boundary layer. LES results are compared with a complete set of surface and upper-air meteorological and carbon-dioxide observations gathered during a representative day at the 213-meter meteorological tall tower at Cabauw. Second, we perform systematic numerical experiments under a wide range of background wind conditions and stomatal aperture response time. Our analysis unravel how thin clouds, characterized by lower values of the cloud optical depth, have a different impact on evapotranspiration compared to thick clouds due to differences in the partitioning between direct and diffuse radiation at canopy level. Related to this detailed simulation, we discuss how new instrumental techniques, e.g. scintillometery, enable us to obtain new observational insight of the coupling between clouds and vegetation. We will close the presentation with open questions regarding the need to include parameterizations for these interactions at short spatiotemporal scales in regional or climate models.

  11. Exploring nonlinear subgrid-scale models and new characteristic length scales for large-eddy simulation

    NARCIS (Netherlands)

    Silvis, Maurits H.; Trias, F. Xavier; Abkar, M.; Bae, H.J.; Lozano-Duran, A.; Verstappen, R.W.C.P.; Moin, Parviz; Urzay, Javier


    We study subgrid-scale modeling for large-eddy simulation of anisotropic turbulent flows on anisotropic grids. In particular, we show how the addition of a velocity-gradient-based nonlinear model term to an eddy viscosity model provides a better representation of energy transfer. This is shown to

  12. Multifractal subgrid-scale modeling within a variational multiscale method for large-eddy simulation of turbulent flow (United States)

    Rasthofer, U.; Gravemeier, V.


    Multifractal subgrid-scale modeling within a variational multiscale method is proposed for large-eddy simulation of turbulent flow. In the multifractal subgrid-scale modeling approach, the subgrid-scale velocity is evaluated from a multifractal description of the subgrid-scale vorticity, which is based on the multifractal scale similarity of gradient fields in turbulent flow. The multifractal subgrid-scale modeling approach is integrated into a variational multiscale formulation, which constitutes a new application of the variational multiscale concept. A focus of this study is on the application of the multifractal subgrid-scale modeling approach to wall-bounded turbulent flow. Therefore, a near-wall limit of the multifractal subgrid-scale modeling approach is derived in this work. The novel computational approach of multifractal subgrid-scale modeling within a variational multiscale formulation is applied to turbulent channel flow at various Reynolds numbers, turbulent flow over a backward-facing step and turbulent flow past a square-section cylinder, which are three of the most important and widely-used benchmark examples for wall-bounded turbulent flow. All results presented in this study confirm a very good performance of the proposed method. Compared to a dynamic Smagorinsky model and a residual-based variational multiscale method, improved results are obtained. Moreover, it is demonstrated that the subgrid-scale energy transfer incorporated by the proposed method very well approximates the expected energy transfer as obtained from appropriately filtered direct numerical simulation data. The computational cost is notably reduced compared to a dynamic Smagorinsky model and only marginally increased compared to a residual-based variational multiscale method.

  13. Stochastic fields method for sub-grid scale emission heterogeneity in mesoscale atmospheric dispersion models


    M. Cassiani; Vinuesa, J.F.; Galmarini, S.; Denby, B


    The stochastic fields method for turbulent reacting flows has been applied to the issue of sub-grid scale emission heterogeneity in a mesoscale model. This method is a solution technique for the probability density function (PDF) transport equation and can be seen as a straightforward extension of currently used mesoscale dispersion models. It has been implemented in an existing mesoscale model and the results are compared with Large-Eddy Simulation (LES) data devised to test specifically the...

  14. Subgrid-scale models for large-eddy simulation of rotating turbulent channel flows (United States)

    Silvis, Maurits H.; Bae, Hyunji Jane; Trias, F. Xavier; Abkar, Mahdi; Moin, Parviz; Verstappen, Roel


    We aim to design subgrid-scale models for large-eddy simulation of rotating turbulent flows. Rotating turbulent flows form a challenging test case for large-eddy simulation due to the presence of the Coriolis force. The Coriolis force conserves the total kinetic energy while transporting it from small to large scales of motion, leading to the formation of large-scale anisotropic flow structures. The Coriolis force may also cause partial flow laminarization and the occurrence of turbulent bursts. Many subgrid-scale models for large-eddy simulation are, however, primarily designed to parametrize the dissipative nature of turbulent flows, ignoring the specific characteristics of transport processes. We, therefore, propose a new subgrid-scale model that, in addition to the usual dissipative eddy viscosity term, contains a nondissipative nonlinear model term designed to capture transport processes, such as those due to rotation. We show that the addition of this nonlinear model term leads to improved predictions of the energy spectra of rotating homogeneous isotropic turbulence as well as of the Reynolds stress anisotropy in spanwise-rotating plane-channel flows. This work is financed by the Netherlands Organisation for Scientific Research (NWO) under Project Number 613.001.212.

  15. Stochastic fields method for sub-grid scale emission heterogeneity in mesoscale atmospheric dispersion models

    Directory of Open Access Journals (Sweden)

    M. Cassiani


    Full Text Available The stochastic fields method for turbulent reacting flows has been applied to the issue of sub-grid scale emission heterogeneity in a mesoscale model. This method is a solution technique for the probability density function (PDF transport equation and can be seen as a straightforward extension of currently used mesoscale dispersion models. It has been implemented in an existing mesoscale model and the results are compared with Large-Eddy Simulation (LES data devised to test specifically the effect of sub-grid scale emission heterogeneity on boundary layer concentration fluctuations. The sub-grid scale emission variability is assimilated in the model as a PDF of the emissions. The stochastic fields method shows excellent agreement with the LES data without adjustment of the constants used in the mesoscale model. The stochastic fields method is a stochastic solution of the transport equations for the concentration PDF of dispersing scalars, therefore it possesses the ability to handle chemistry of any complexity without the need to introduce additional closures for the high order statistics of chemical species. This study shows for the first time the feasibility of applying this method to mesoscale chemical transport models.

  16. Importance of subgrid-scale parameterization in numerical simulations of lake circulation (United States)

    Wang, Yongqi

    Two subgrid-scale modeling techniques--Smagorinsky's postulation for the horizontal eddy viscosity and the Mellor-Yamada level-2 model for the vertical eddy viscosity--are applied as turbulence closure conditions to numerical simulations of resolved-scale baroclinic lake circulations. The use of the total variation diminishing (TVD) technique in the numerical treatment of the advection terms in the governing equations depresses numerical diffusion to an acceptably low level and makes stable numerical performances possible with small eddy viscosities resulting from the turbulence closure parameterizations. The results show that, with regard to the effect of an external wind stress, the vertical turbulent mixing is mainly restricted to the topmost epilimnion with the order of magnitude for the vertical eddy viscosity of 10 -3 m 2 s -1, whilst the horizontal turbulent mixing may reach a somewhat deeper zone with an order of magnitude for the horizontal eddy viscosity of 0.1-1 m 2 s -1. Their spatial and temporal variations and influences on numerical results are significant. A comparison with prescribed constant eddy viscosities clearly shows the importance of subgrid-scale closures on resolved-scale flows in the lake circulation simulation. A predetermination of the eddy viscosities is inappropriate and should be abandoned. Their values must be determined by suitable subgrid-scale closure techniques.

  17. Lagrangian scheme to model subgrid-scale mixing and spreading in heterogeneous porous media (United States)

    Herrera, P. A.; Cortínez, J. M.; Valocchi, A. J.


    Small-scale heterogeneity of permeability controls spreading, dilution, and mixing of solute plumes at large scale. However, conventional numerical simulations of solute transport are unable to resolve scales of heterogeneity below the grid scale. We propose a Lagrangian numerical approach to implement closure models to account for subgrid-scale spreading and mixing in Darcy-scale numerical simulations of solute transport in mildly heterogeneous porous media. The novelty of the proposed approach is that it considers two different dispersion coefficients to account for advective spreading mechanisms and local-scale dispersion. Using results of benchmark numerical simulations, we demonstrate that the proposed approach is able to model subgrid-scale spreading and mixing provided there is a correct choice of block-scale dispersion coefficient. We also demonstrate that for short travel times it is only possible to account for spreading or mixing using a single block-scale dispersion coefficient. Moreover, we show that it is necessary to use time-dependent dispersion coefficients to obtain correct mixing rates. On the contrary, for travel times that are large in comparison to the typical dispersive time scale, it is possible to use a single expression to compute the block-dispersion coefficient, which is equal to the asymptotic limit of the block-scale macrodispersion coefficient proposed by Rubin et al. (1999). Our approach provides a flexible and efficient way to model subgrid-scale mixing in numerical models of large-scale solute transport in heterogeneous aquifers. We expect that these findings will help to better understand the applicability of the advection-dispersion-equation (ADE) to simulate solute transport at the Darcy scale in heterogeneous porous media.

  18. Improving sub-grid scale accuracy of boundary features in regional finite-difference models (United States)

    Panday, Sorab; Langevin, Christian D.


    As an alternative to grid refinement, the concept of a ghost node, which was developed for nested grid applications, has been extended towards improving sub-grid scale accuracy of flow to conduits, wells, rivers or other boundary features that interact with a finite-difference groundwater flow model. The formulation is presented for correcting the regular finite-difference groundwater flow equations for confined and unconfined cases, with or without Newton Raphson linearization of the nonlinearities, to include the Ghost Node Correction (GNC) for location displacement. The correction may be applied on the right-hand side vector for a symmetric finite-difference Picard implementation, or on the left-hand side matrix for an implicit but asymmetric implementation. The finite-difference matrix connectivity structure may be maintained for an implicit implementation by only selecting contributing nodes that are a part of the finite-difference connectivity. Proof of concept example problems are provided to demonstrate the improved accuracy that may be achieved through sub-grid scale corrections using the GNC schemes.

  19. Large eddy simulation of flow over a wall-mounted cube: Comparison of different semi dynamic subgrid scale models

    Directory of Open Access Journals (Sweden)

    M Nooroullahi


    Full Text Available In this paper the ability of different semi dynamic subgrid scale models for large eddy simulation was studied in a challenging test case. The semi dynamic subgrid scale models were examined in this investigation is Selective Structure model, Coherent structure model, Wall Adaptive Large Eddy model. The test case is a simulation of flow over a wall-mounted cube in a channel. The results of these models were compared to structure function model, dynamic models and experimental data at Reynolds number 40000. Results show that these semi dynamic models could improve the ability of numerical simulation in comparison with other models which use a constant coefficient for simulation of subgrid scale viscosity. In addition, these models don't have the instability problems of dynamic models.

  20. Effects of Implementing Subgrid-Scale Cloud-Radiation Interactions in a Regional Climate Model (United States)

    Herwehe, J. A.; Alapaty, K.; Otte, T.; Nolte, C. G.


    Interactions between atmospheric radiation, clouds, and aerosols are the most important processes that determine the climate and its variability. In regional scale models, when used at relatively coarse spatial resolutions (e.g., larger than 1 km), convective cumulus clouds need to be parameterized as subgrid-scale clouds. Like many groups, our regional climate modeling group at the EPA uses the Weather Research & Forecasting model (WRF) as a regional climate model (RCM). One of the findings from our RCM studies is that the summertime convective systems simulated by the WRF model are highly energetic, leading to excessive surface precipitation. We also found that the WRF model does not consider the interactions between convective clouds and radiation, thereby omitting an important process that drives the climate. Thus, the subgrid-scale cloudiness associated with convective clouds (from shallow cumuli to thunderstorms) does not exist and radiation passes through the atmosphere nearly unimpeded, potentially leading to overly energetic convection. This also has implications for air quality modeling systems that are dependent upon cloud properties from the WRF model, as the failure to account for subgrid-scale cloudiness can lead to problems such as the underrepresentation of aqueous chemistry processes within clouds and the overprediction of ozone from overactive photolysis. In an effort to advance the climate science of the cloud-aerosol-radiation (CAR) interactions in RCM systems, as a first step we have focused on linking the cumulus clouds with the radiation processes. To this end, our research group has implemented into WRF's Kain-Fritsch (KF) cumulus parameterization a cloudiness formulation that is widely used in global earth system models (e.g., CESM/CAM5). Estimated grid-scale cloudiness and associated condensate are adjusted to account for the subgrid clouds and then passed to WRF's Rapid Radiative Transfer Model - Global (RRTMG) radiation schemes to affect

  1. Evaluation of Subgrid-Scale Transport of Hydrometeors in a PDF-based Scheme using High-Resolution CRM Simulations (United States)

    Wong, M.; Ovchinnikov, M.; Wang, M.; Larson, V. E.


    In current climate models, the model resolution is too coarse to explicitly resolve deep convective systems. Parameterization schemes are therefore needed to represent the physical processes at the sub-grid scale. Recently, an approach based on assumed probability density functions (PDFs) has been developed to help unify the various parameterization schemes used in current global models. In particular, a unified parameterization scheme called the Cloud Layers Unified By Binormals (CLUBB) scheme has been developed and tested successfully for shallow boundary-layer clouds. CLUBB's implementation in the Community Atmosphere Model, version 5 (CAM5) is also being extended to treat deep convection cases, but parameterizing subgrid-scale vertical transport of hydrometeors remains a challenge. To investigate the roots of the problem and possible solutions, we generate a high-resolution benchmark simulation of a deep convection case using a cloud-resolving model (CRM) called System for Atmospheric Modeling (SAM). We use the high-resolution 3D CRM results to assess the prognostic and diagnostic higher-order moments in CLUBB that are in relation to the subgrid-scale transport of hydrometeors. We also analyze the heat and moisture budgets in terms of CLUBB variables from the SAM benchmark simulation. The results from this study will be used to devise a better representation of vertical subgrid-scale transport of hydrometeors by utilizing the sub-grid variability information from CLUBB.

  2. Subgrid-scale stresses and scalar fluxes constructed by the multi-scale turnover Lagrangian map (United States)

    AL-Bairmani, Sukaina; Li, Yi; Rosales, Carlos; Xie, Zheng-tong


    The multi-scale turnover Lagrangian map (MTLM) [C. Rosales and C. Meneveau, "Anomalous scaling and intermittency in three-dimensional synthetic turbulence," Phys. Rev. E 78, 016313 (2008)] uses nested multi-scale Lagrangian advection of fluid particles to distort a Gaussian velocity field and, as a result, generate non-Gaussian synthetic velocity fields. Passive scalar fields can be generated with the procedure when the fluid particles carry a scalar property [C. Rosales, "Synthetic three-dimensional turbulent passive scalar fields via the minimal Lagrangian map," Phys. Fluids 23, 075106 (2011)]. The synthetic fields have been shown to possess highly realistic statistics characterizing small scale intermittency, geometrical structures, and vortex dynamics. In this paper, we present a study of the synthetic fields using the filtering approach. This approach, which has not been pursued so far, provides insights on the potential applications of the synthetic fields in large eddy simulations and subgrid-scale (SGS) modelling. The MTLM method is first generalized to model scalar fields produced by an imposed linear mean profile. We then calculate the subgrid-scale stress, SGS scalar flux, SGS scalar variance, as well as related quantities from the synthetic fields. Comparison with direct numerical simulations (DNSs) shows that the synthetic fields reproduce the probability distributions of the SGS energy and scalar dissipation rather well. Related geometrical statistics also display close agreement with DNS results. The synthetic fields slightly under-estimate the mean SGS energy dissipation and slightly over-predict the mean SGS scalar variance dissipation. In general, the synthetic fields tend to slightly under-estimate the probability of large fluctuations for most quantities we have examined. Small scale anisotropy in the scalar field originated from the imposed mean gradient is captured. The sensitivity of the synthetic fields on the input spectra is assessed by

  3. Numerical dissipation vs. subgrid-scale modelling for large eddy simulation (United States)

    Dairay, Thibault; Lamballais, Eric; Laizet, Sylvain; Vassilicos, John Christos


    This study presents an alternative way to perform large eddy simulation based on a targeted numerical dissipation introduced by the discretization of the viscous term. It is shown that this regularisation technique is equivalent to the use of spectral vanishing viscosity. The flexibility of the method ensures high-order accuracy while controlling the level and spectral features of this purely numerical viscosity. A Pao-like spectral closure based on physical arguments is used to scale this numerical viscosity a priori. It is shown that this way of approaching large eddy simulation is more efficient and accurate than the use of the very popular Smagorinsky model in standard as well as in dynamic version. The main strength of being able to correctly calibrate numerical dissipation is the possibility to regularise the solution at the mesh scale. Thanks to this property, it is shown that the solution can be seen as numerically converged. Conversely, the two versions of the Smagorinsky model are found unable to ensure regularisation while showing a strong sensitivity to numerical errors. The originality of the present approach is that it can be viewed as implicit large eddy simulation, in the sense that the numerical error is the source of artificial dissipation, but also as explicit subgrid-scale modelling, because of the equivalence with spectral viscosity prescribed on a physical basis.

  4. A nonlinear structural subgrid-scale closure for compressible MHD. I. Derivation and energy dissipation properties

    Energy Technology Data Exchange (ETDEWEB)

    Vlaykov, Dimitar G., E-mail: [Institut für Astrophysik, Universität Göttingen, Friedrich-Hund-Platz 1, D-37077 Göttingen (Germany); Max-Planck-Institut für Dynamik und Selbstorganisation, Am Faßberg 17, D-37077 Göttingen (Germany); Grete, Philipp [Institut für Astrophysik, Universität Göttingen, Friedrich-Hund-Platz 1, D-37077 Göttingen (Germany); Max-Planck-Institut für Sonnensystemforschung, Justus-von-Liebig-Weg 3, D-37077 Göttingen (Germany); Schmidt, Wolfram [Hamburger Sternwarte, Universität Hamburg, Gojenbergsweg 112, D-21029 Hamburg (Germany); Schleicher, Dominik R. G. [Departamento de Astronomía, Facultad Ciencias Físicas y Matemáticas, Universidad de Concepción, Av. Esteban Iturra s/n Barrio Universitario, Casilla 160-C (Chile)


    Compressible magnetohydrodynamic (MHD) turbulence is ubiquitous in astrophysical phenomena ranging from the intergalactic to the stellar scales. In studying them, numerical simulations are nearly inescapable, due to the large degree of nonlinearity involved. However, the dynamical ranges of these phenomena are much larger than what is computationally accessible. In large eddy simulations (LESs), the resulting limited resolution effects are addressed explicitly by introducing to the equations of motion additional terms associated with the unresolved, subgrid-scale dynamics. This renders the system unclosed. We derive a set of nonlinear structural closures for the ideal MHD LES equations with particular emphasis on the effects of compressibility. The closures are based on a gradient expansion of the finite-resolution operator [W. K. Yeo (CUP, 1993)] and require no assumptions about the nature of the flow or magnetic field. Thus, the scope of their applicability ranges from the sub- to the hyper-sonic and -Alfvénic regimes. The closures support spectral energy cascades both up and down-scale, as well as direct transfer between kinetic and magnetic resolved and unresolved energy budgets. They implicitly take into account the local geometry, and in particular, the anisotropy of the flow. Their properties are a priori validated in Paper II [P. Grete et al., Phys. Plasmas 23, 062317 (2016)] against alternative closures available in the literature with respect to a wide range of simulation data of homogeneous and isotropic turbulence.

  5. A priori study of subgrid-scale features in turbulent Rayleigh-Bénard convection (United States)

    Dabbagh, F.; Trias, F. X.; Gorobets, A.; Oliva, A.


    At the crossroad between flow topology analysis and turbulence modeling, a priori studies are a reliable tool to understand the underlying physics of the subgrid-scale (SGS) motions in turbulent flows. In this paper, properties of the SGS features in the framework of a large-eddy simulation are studied for a turbulent Rayleigh-Bénard convection (RBC). To do so, data from direct numerical simulation (DNS) of a turbulent air-filled RBC in a rectangular cavity of aspect ratio unity and π spanwise open-ended distance are used at two Rayleigh numbers R a ∈{1 08,1 010 } [Dabbagh et al., "On the evolution of flow topology in turbulent Rayleigh-Bénard convection," Phys. Fluids 28, 115105 (2016)]. First, DNS at Ra = 108 is used to assess the performance of eddy-viscosity models such as QR, Wall-Adapting Local Eddy-viscosity (WALE), and the recent S3PQR-models proposed by Trias et al. ["Building proper invariants for eddy-viscosity subgrid-scale models," Phys. Fluids 27, 065103 (2015)]. The outcomes imply that the eddy-viscosity modeling smoothes the coarse-grained viscous straining and retrieves fairly well the effect of the kinetic unfiltered scales in order to reproduce the coherent large scales. However, these models fail to approach the exact evolution of the SGS heat flux and are incapable to reproduce well the further dominant rotational enstrophy pertaining to the buoyant production. Afterwards, the key ingredients of eddy-viscosity, νt, and eddy-diffusivity, κt, are calculated a priori and revealed positive prevalent values to maintain a turbulent wind essentially driven by the mean buoyant force at the sidewalls. The topological analysis suggests that the effective turbulent diffusion paradigm and the hypothesis of a constant turbulent Prandtl number are only applicable in the large-scale strain-dominated areas in the bulk. It is shown that the bulk-dominated rotational structures of vortex-stretching (and its synchronous viscous dissipative structures) hold

  6. Convective kinetic energy equation under the mass-flux subgrid-scale parameterization (United States)

    Yano, Jun-Ichi


    The present paper originally derives the convective kinetic energy equation under mass-flux subgrid-scale parameterization in a formal manner based on the segmentally-constant approximation (SCA). Though this equation is long since presented by Arakawa and Schubert (1974), a formal derivation is not known in the literature. The derivation of this formulation is of increasing interests in recent years due to the fact that it can explain basic aspects of the convective dynamics such as discharge-recharge and transition from shallow to deep convection. The derivation is presented in two manners: (i) for the case that only the vertical component of the velocity is considered and (ii) the case that both the horizontal and vertical components are considered. The equation reduces to the same form as originally presented by Arakwa and Schubert in both cases, but with the energy dissipation term defined differently. In both cases, nevertheless, the energy "dissipation" (loss) term consists of the three principal contributions: (i) entrainment-detrainment, (ii) outflow from top of convection, and (iii) pressure effects. Additionally, inflow from the bottom of convection contributing to a growth of convection is also formally counted as a part of the dissipation term. The eddy dissipation is also included for a completeness. The order-of-magnitude analysis shows that the convective kinetic energy "dissipation" is dominated by the pressure effects, and it may be approximately described by Rayleigh damping with a constant time scale of the order of 102-103 s. The conclusion is also supported by a supplementary analysis of a cloud-resolving model (CRM) simulation. The Appendix discusses how the loss term ("dissipation") of the convective kinetic energy is qualitatively different from the conventional eddy-dissipation process found in turbulent flows.

  7. A dynamic subgrid scale model for Large Eddy Simulations based on the Mori-Zwanzig formalism (United States)

    Parish, Eric J.; Duraisamy, Karthik


    The development of reduced models for complex multiscale problems remains one of the principal challenges in computational physics. The optimal prediction framework of Chorin et al. [1], which is a reformulation of the Mori-Zwanzig (M-Z) formalism of non-equilibrium statistical mechanics, provides a framework for the development of mathematically-derived reduced models of dynamical systems. Several promising models have emerged from the optimal prediction community and have found application in molecular dynamics and turbulent flows. In this work, a new M-Z-based closure model that addresses some of the deficiencies of existing methods is developed. The model is constructed by exploiting similarities between two levels of coarse-graining via the Germano identity of fluid mechanics and by assuming that memory effects have a finite temporal support. The appeal of the proposed model, which will be referred to as the 'dynamic-MZ-τ' model, is that it is parameter-free and has a structural form imposed by the mathematics of the coarse-graining process (rather than the phenomenological assumptions made by the modeler, such as in classical subgrid scale models). To promote the applicability of M-Z models in general, two procedures are presented to compute the resulting model form, helping to bypass the tedious error-prone algebra that has proven to be a hindrance to the construction of M-Z-based models for complex dynamical systems. While the new formulation is applicable to the solution of general partial differential equations, demonstrations are presented in the context of Large Eddy Simulation closures for the Burgers equation, decaying homogeneous turbulence, and turbulent channel flow. The performance of the model and validity of the underlying assumptions are investigated in detail.

  8. Free energy landscape of protein-like chains with discontinuous potentials (United States)

    Movahed, Hanif Bayat; van Zon, Ramses; Schofield, Jeremy


    In this article the configurational space of two simple protein models consisting of polymers composed of a periodic sequence of four different kinds of monomers is studied as a function of temperature. In the protein models, hydrogen bond interactions, electrostatic repulsion, and covalent bond vibrations are modeled by discontinuous step, shoulder, and square-well potentials, respectively. The protein-like chains exhibit a secondary alpha helix structure in their folded states at low temperatures, and allow a natural definition of a configuration by considering which beads are bonded. Free energies and entropies of configurations are computed using the parallel tempering method in combination with hybrid Monte Carlo sampling of the canonical ensemble of the discontinuous potential system. The probability of observing the most common configuration is used to analyze the nature of the free energy landscape, and it is found that the model with the least number of possible bonds exhibits a funnel-like free energy landscape at low enough temperature for chains with fewer than 30 beads. For longer proteins, the free landscape consists of several minima, where the configuration with the lowest free energy changes significantly by lowering the temperature and the probability of observing the most common configuration never approaches one due to the degeneracy of the lowest accessible potential energy.

  9. A nonlinear structural subgrid-scale closure for compressible MHD Part I: derivation and energy dissipation properties

    CERN Document Server

    Vlaykov, Dimitar G; Schmidt, Wolfram; Schleicher, Dominik R G


    Compressible magnetohydrodynamic (MHD) turbulence is ubiquitous in astrophysical phenomena ranging from the intergalactic to the stellar scales. In studying them, numerical simulations are nearly inescapable, due to the large degree of nonlinearity involved. However the dynamical ranges of these phenomena are much larger than what is computationally accessible. In large eddy simulations (LES), the resulting limited resolution effects are addressed explicitly by introducing to the equations of motion additional terms associated with the unresolved, subgrid-scale (SGS) dynamics. This renders the system unclosed. We derive a set of nonlinear structural closures for the ideal MHD LES equations with particular emphasis on the effects of compressibility. The closures are based on a gradient expansion of the finite-resolution operator (W.K. Yeo CUP 1993, ed. Galperin & Orszag) and require no assumptions about the nature of the flow or magnetic field. Thus the scope of their applicability ranges from the sub- to ...

  10. A nonlinear structural subgrid-scale closure for compressible MHD Part II: a priori comparison on turbulence simulation data

    CERN Document Server

    Grete, P; Schmidt, W; Schleicher, D R G


    Even though compressible plasma turbulence is encountered in many astrophysical phenomena, its effect is often not well understood. Furthermore, direct numerical simulations are typically not able to reach the extreme parameters of these processes. For this reason, large-eddy simulations (LES), which only simulate large and intermediate scales directly, are employed. The smallest, unresolved scales and the interactions between small and large scales are introduced by means of a subgrid-scale (SGS) model. We propose and verify a new set of nonlinear SGS closures for future application as an SGS model in LES of compressible magnetohydrodynamics (MHD). We use 15 simulations (without explicit SGS model) of forced, isotropic, homogeneous turbulence with varying sonic Mach number $\\mathrm{M_s} = 0.2$ to $20$ as reference data for the most extensive \\textit{a priori} tests performed so far in literature. In these tests we explicitly filter the reference data and compare the performance of the new closures against th...

  11. One-equation sub-grid scale (SGS) modelling for Euler-Euler large eddy simulation (EELES) of dispersed bubbly flow

    NARCIS (Netherlands)

    Niceno, B.; Dhotre, M.T.; Deen, N.G.


    In this work, we have presented a one-equation model for sub-grid scale (SGS) kinetic energy and applied it for an Euler-Euler large eddy simulation (EELES) of a bubble column reactor. The one-equation model for SGS kinetic energy shows improved predictions over the state-of-the-art dynamic

  12. Large Eddy Simulation of an SD7003 Airfoil: Effects of Reynolds number and Subgrid-scale modeling (United States)

    Sarlak, Hamid


    This paper presents results of a series of numerical simulations in order to study aerodynamic characteristics of the low Reynolds number Selig-Donovan airfoil, SD7003. Large Eddy Simulation (LES) technique is used for all computations at chord-based Reynolds numbers 10,000, 24,000 and 60,000 and simulations have been performed to primarily investigate the role of sub-grid scale (SGS) modeling on the dynamics of flow generated over the airfoil, which has not been dealt with in great detail in the past. It is seen that simulations are increasingly getting influenced by SGS modeling with increasing the Reynolds number, and the effect is visible even at a relatively low chord-Reynolds number of 60,000. Among the tested models, the dynamic Smagorinsky gives the poorest predictions of the flow, with overprediction of lift and a larger separation on airfoils suction side. Among various models, the implicit LES offers closest pressure distribution predictions compared with literature.

  13. A new mixed subgrid-scale model for large eddy simulation of turbulent drag-reducing flows of viscoelastic fluids (United States)

    Li, Feng-Chen; Wang, Lu; Cai, Wei-Hua


    A mixed subgrid-scale (SGS) model based on coherent structures and temporal approximate deconvolution (MCT) is proposed for turbulent drag-reducing flows of viscoelastic fluids. The main idea of the MCT SGS model is to perform spatial filtering for the momentum equation and temporal filtering for the conformation tensor transport equation of turbulent flow of viscoelastic fluid, respectively. The MCT model is suitable for large eddy simulation (LES) of turbulent drag-reducing flows of viscoelastic fluids in engineering applications since the model parameters can be easily obtained. The LES of forced homogeneous isotropic turbulence (FHIT) with polymer additives and turbulent channel flow with surfactant additives based on MCT SGS model shows excellent agreements with direct numerical simulation (DNS) results. Compared with the LES results using the temporal approximate deconvolution model (TADM) for FHIT with polymer additives, this mixed SGS model MCT behaves better, regarding the enhancement of calculating parameters such as the Reynolds number. For scientific and engineering research, turbulent flows at high Reynolds numbers are expected, so the MCT model can be a more suitable model for the LES of turbulent drag-reducing flows of viscoelastic fluid with polymer or surfactant additives. Project supported by the China Postdoctoral Science Foundation (Grant No. 2011M500652), the National Natural Science Foundation of China (Grant Nos. 51276046 and 51206033), and the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20112302110020).

  14. Assessment of sub-grid scale dispersion closure with regularized deconvolution method in a particle-laden turbulent jet (United States)

    Wang, Qing; Zhao, Xinyu; Ihme, Matthias


    Particle-laden turbulent flows are important in numerous industrial applications, such as spray combustion engines, solar energy collectors etc. It is of interests to study this type of flows numerically, especially using large-eddy simulations (LES). However, capturing the turbulence-particle interaction in LES remains challenging due to the insufficient representation of the effect of sub-grid scale (SGS) dispersion. In the present work, a closure technique for the SGS dispersion using regularized deconvolution method (RDM) is assessed. RDM was proposed as the closure for the SGS dispersion in a counterflow spray that is studied numerically using finite difference method on a structured mesh. A presumed form of LES filter is used in the simulations. In the present study, this technique has been extended to finite volume method with an unstructured mesh, where no presumption on the filter form is required. The method is applied to a series of particle-laden turbulent jets. Parametric analyses of the model performance are conducted for flows with different Stokes numbers and Reynolds numbers. The results from LES will be compared against experiments and direct numerical simulations (DNS).

  15. A Physically Based Horizontal Subgrid-scale Turbulent Mixing Parameterization for the Convective Boundary Layer in Mesoscale Models (United States)

    Zhou, Bowen; Xue, Ming; Zhu, Kefeng


    Compared to the representation of vertical turbulent mixing through various PBL schemes, the treatment of horizontal turbulence mixing in the boundary layer within mesoscale models, with O(10) km horizontal grid spacing, has received much less attention. In mesoscale models, subgrid-scale horizontal fluxes most often adopt the gradient-diffusion assumption. The horizontal mixing coefficients are usually set to a constant, or through the 2D Smagorinsky formulation, or in some cases based on the 1.5-order turbulence kinetic energy (TKE) closure. In this work, horizontal turbulent mixing parameterizations using physically based characteristic velocity and length scales are proposed for the convective boundary layer based on analysis of a well-resolved, wide-domain large-eddy simulation (LES). The proposed schemes involve different levels of sophistication. The first two schemes can be used together with first-order PBL schemes, while the third uses TKE to define its characteristic velocity scale and can be used together with TKE-based higher-order PBL schemes. The current horizontal mixing formulations are also assessed a priori through the filtered LES results to illustrate their limitations. The proposed parameterizations are tested a posteriori in idealized simulations of turbulent dispersion of a passive scalar. Comparisons show improved horizontal dispersion by the proposed schemes, and further demonstrate the weakness of the current schemes.

  16. Exploring the Limits of the Dynamic Procedure for Modeling Subgrid-Scale Stresses in LES of Inhomogeneous Flows. (United States)

    Le, A.-T.; Kim, J.; Coleman, G.


    One of the primary reasons dynamic subgrid-scale (SGS) models are more successful than those that are `hand-tuned' is thought to be their insensitivity to numerical and modeling parameters. Jiménez has recently demonstrated that large-eddy simulations (LES) of decaying isotropic turbulence using a dynamic Smagorinsky model yield correct decay rates -- even when the model is subjected to a range of artificial perturbations. The objective of the present study is to determine to what extent this `self-adjusting' feature of dynamic SGS models is found in LES of inhomogeneous flows. The effects of numerical and modeling parameters on the accuracy of LES solutions of fully developed and developing turbulent channel flow are studied, using a spectral code and various dynamic models (including those of Lilly et al. and Meneveau et al.); other modeling parameters tested include the filter-width ratio and the effective magnitude of the Smagorinsky coefficient. Numerical parameters include the form of the convective term and the type of test filter (sharp-cutoff versus tophat). The resulting LES statistics are found to be surprisingly sensitive to the various parameter choices, which implies that more care than is needed for homogeneous-flow simulations must be exercised when performing LES of inhomogeneous flows.

  17. Final Report. Evaluating the Climate Sensitivity of Dissipative Subgrid-Scale Mixing Processes and Variable Resolution in NCAR's Community Earth System Model

    Energy Technology Data Exchange (ETDEWEB)

    Jablonowski, Christiane [Univ. of Michigan, Ann Arbor, MI (United States)


    The goals of this project were to (1) assess and quantify the sensitivity and scale-dependency of unresolved subgrid-scale mixing processes in NCAR’s Community Earth System Model (CESM), and (2) to improve the accuracy and skill of forthcoming CESM configurations on modern cubed-sphere and variable-resolution computational grids. The research thereby contributed to the description and quantification of uncertainties in CESM’s dynamical cores and their physics-dynamics interactions.

  18. Resolution-dependent behavior of subgrid-scale vertical transport in the Zhang-McFarlane convection parameterization (United States)

    Xiao, Heng; Gustafson, William I.; Hagos, Samson M.; Wu, Chien-Ming; Wan, Hui


    To better understand the behavior of quasi-equilibrium-based convection parameterizations at higher resolution, we use a diagnostic framework to examine the resolution-dependence of subgrid-scale vertical transport of moist static energy as parameterized by the Zhang-McFarlane convection parameterization (ZM). Grid-scale input to ZM is supplied by coarsening output from cloud-resolving model (CRM) simulations onto subdomains ranging in size from 8 × 8 to 256 × 256 km2. Then the ZM-based parameterization of vertical transport of moist static energy for scales smaller than the subdomain size (w'h'>¯ZM) are compared to those directly calculated from the CRM simulations (w'h'>¯CRM) for different subdomain sizes. The ensemble mean w'h'>¯CRM decreases by more than half as the subdomain size decreases from 128 to 8 km across while w'h'>¯ZM decreases with subdomain size only for strong convection cases and increases for weaker cases. The resolution dependence of w'h'>¯ZM is determined by the positive-definite grid-scale tendency of convective available potential energy (CAPE) in the convective quasi-equilibrium (QE) closure. Further analysis shows the actual grid-scale tendency of CAPE (before taking the positive definite value) and w'h'>¯CRM behave very similarly as the subdomain size changes because they are both tied to grid-scale advective tendencies. We can improve the resolution dependence of w'h'>¯ZM significantly by averaging the grid-scale tendency of CAPE over an appropriately large area surrounding each subdomain before taking its positive definite value. Even though the ensemble mean w'h'>¯CRM decreases with increasing resolution, its variability increases dramatically. w'h'>¯ZM cannot capture such increase in the variability, suggesting the need for stochastic treatment of convection at relatively high spatial resolution (8 or 16 km).

  19. Simple lattice Boltzmann subgrid-scale model for convectional flows with high Rayleigh numbers within an enclosed circular annular cavity (United States)

    Chen, Sheng; Tölke, Jonas; Krafczyk, Manfred


    Natural convection within an enclosed circular annular cavity formed by two concentric vertical cylinders is of fundamental interest and practical importance. Generally, the assumption of axisymmetric thermal flow is adopted for simulating such natural convections and the validity of the assumption of axisymmetric thermal flow is still held even for some turbulent convection. Usually the Rayleigh numbers (Ra) of realistic flows are very high. However, the work to design suitable and efficient lattice Boltzmann (LB) models on such flows is quite rare. To bridge the gap, in this paper a simple LB subgrid-scale (SGS) model, which is based on our recent work [S. Chen, J. Tölke, and M. Krafczyk, Phys. Rev. E 79, 016704 (2009); S. Chen, J. Tölke, S. Geller, and M. Krafczyk, Phys. Rev. E 78, 046703 (2008)], is proposed for simulating convectional flow with high Ra within an enclosed circular annular cavity. The key parameter for the SGS model can be quite easily and efficiently evaluated by the present model. The numerical experiments demonstrate that the present model works well for a large range of Ra and Prandtl number (Pr). Though in the present study a popularly used static Smagorinsky turbulence model is adopted to demonstrate how to develop a LB SGS model for simulating axisymmetric thermal flows with high Ra, other state-of-the-art turbulence models can be incorporated into the present model in the same way. In addition, the present model can be extended straightforwardly to simulate other axisymmetric convectional flows with high Ra, for example, turbulent convection with internal volumetric heat generation in a vertical cylinder, which is an important simplified representation of a nuclear reactor.

  20. Stable carbon isotopic signature of methane from high-emitting wetland sites in discontinuous permafrost landscape (United States)

    Marushchak, Maija; Liimatainen, Maarit; Lind, Saara; Biasi, Christina; Martikainen, Pertti


    The rising methane concentration in the atmosphere during the past years has been associated with a concurrent change in the carbon isotopic signature: The atmospheric methane is getting more and more depleted in the heavy carbon isotope. The decreasing 13C/12C ratio indicates an increasing contribution of methane from biogenic sources, most importantly wetlands and inland waters, whose global emissions are still poorly constrained. From the climate change perspective, arctic and subarctic wetlands are particularly interesting due to the strong warming and permafrost thaw predicted for these regions that will cause changes in the methane dynamics. Coupling methane flux inventories with determination of the stable isotopic signature can provide useful information about the pathways of methane production, consumption and transport in these ecosystems. Here, we present data on the emissions and carbon isotopic composition of methane from subarctic tundra wetlands at the Seida study site, Northeast European Russia. In this landscape, underlain by discontinuous permafrost, waterlogged fens represent sites of high carbon turnover and high methane release. Despite they cover less than 15% of the region, their methane emissions comprise 98% of the regional mean (± SD) release of 6.7 (± 1.8) g CH4 m-2 y-1 (Marushchak et al. 2016). The methane emission from the studied fens was clearly depleted in 13C compared to the pore water methane. The bulk mean δ13CH4 (± SD) over the growing season was -68.2 (± 2.0) ‰ which is similar to the relatively few values previously reported from tundra wetlands. We explain the depleted methane emissions by the high importance of passive transport via aerenchymous plants, a process that discriminates against the heavier isotopes. This idea is supported by the strong positive correlation observed between the methane emission and the vascular leaf area index (LAI), and the inverse relationship between the δ13CH4 of emitted methane and LAI

  1. Effect of Considering Sub-Grid Scale Uncertainties on the Forecasts of a High-Resolution Limited Area Ensemble Prediction System (United States)

    Kim, SeHyun; Kim, Hyun Mee


    The ensemble prediction system (EPS) is widely used in research and at operation center because it can represent the uncertainty of predicted atmospheric state and provide information of probabilities. The high-resolution (so-called "convection-permitting") limited area EPS can represent the convection and turbulence related to precipitation phenomena in more detail, but it is also much sensitive to small-scale or sub-grid scale processes. The convection and turbulence are represented using physical processes in the model and model errors occur due to sub-grid scale processes that were not resolved. This study examined the effect of considering sub-grid scale uncertainties using the high-resolution limited area EPS of the Korea Meteorological Administration (KMA). The developed EPS has horizontal resolution of 3 km and 12 ensemble members. The initial and boundary conditions were provided by the global model. The Random Parameters (RP) scheme was used to represent sub-grid scale uncertainties. The EPSs with and without the RP scheme were developed and the results were compared. During the one month period of July, 2013, a significant difference was shown in the spread of 1.5 m temperature and the Root Mean Square Error and spread of 10 m zonal wind due to application of the RP scheme. For precipitation forecast, the precipitation tended to be overestimated relative to the observation when the RP scheme was applied. Moreover, the forecast became more accurate for heavy precipitations and the longer forecast lead times. For two heavy rainfall cases occurred during the research period, the higher Equitable Threat Score was observed for heavy precipitations in the system with the RP scheme compared to the one without, demonstrating consistency with the statistical results for the research period. Therefore, the predictability for heavy precipitation phenomena that affected the Korean Peninsula increases if the RP scheme is used to consider sub-grid scale uncertainties in forecasting precipitation phenomena using the high-resolution limited area EPS of KMA.

  2. Sub-grid scale representation of vegetation in global land surface schemes: implications for estimation of the terrestrial carbon sink

    Directory of Open Access Journals (Sweden)

    J. R. Melton


    Full Text Available Terrestrial ecosystem models commonly represent vegetation in terms of plant functional types (PFTs and use their vegetation attributes in calculations of the energy and water balance as well as to investigate the terrestrial carbon cycle. Sub-grid scale variability of PFTs in these models is represented using different approaches with the "composite" and "mosaic" approaches being the two end-members. The impact of these two approaches on the global carbon balance has been investigated with the Canadian Terrestrial Ecosystem Model (CTEM v 1.2 coupled to the Canadian Land Surface Scheme (CLASS v 3.6. In the composite (single-tile approach, the vegetation attributes of different PFTs present in a grid cell are aggregated and used in calculations to determine the resulting physical environmental conditions (soil moisture, soil temperature, etc. that are common to all PFTs. In the mosaic (multi-tile approach, energy and water balance calculations are performed separately for each PFT tile and each tile's physical land surface environmental conditions evolve independently. Pre-industrial equilibrium CLASS-CTEM simulations yield global totals of vegetation biomass, net primary productivity, and soil carbon that compare reasonably well with observation-based estimates and differ by less than 5% between the mosaic and composite configurations. However, on a regional scale the two approaches can differ by > 30%, especially in areas with high heterogeneity in land cover. Simulations over the historical period (1959–2005 show different responses to evolving climate and carbon dioxide concentrations from the two approaches. The cumulative global terrestrial carbon sink estimated over the 1959–2005 period (excluding land use change (LUC effects differs by around 5% between the two approaches (96.3 and 101.3 Pg, for the mosaic and composite approaches, respectively and compares well with the observation-based estimate of 82.2 ± 35 Pg C over the same period. Inclusion of LUC causes the estimates of the terrestrial C sink to differ by 15.2 Pg C (16% with values of 95.1 and 79.9 Pg C for the mosaic and composite approaches, respectively. Spatial differences in simulated vegetation and soil carbon and the manner in which terrestrial carbon balance evolves in response to LUC, in the two approaches, yields a substantially different estimate of the global land carbon sink. These results demonstrate that the spatial representation of vegetation has an important impact on the model response to changing climate, atmospheric CO2 concentrations, and land cover.

  3. Stratigraphical discontinuities, tropical landscape evolution and soil distribution relationships in a case study in SE-Brazil

    Directory of Open Access Journals (Sweden)

    M. Cooper


    Full Text Available On a regional summit surface in the county of Piracicaba (SP within the Peripheric Depression of São Paulo, formed of discontinued flattened tops, there is an abrupt transition between a Typic Hapludox and a Kandiudalfic Eutrudox, together with two stoneline layers. Using stratigraphical, mineralogical, and cartographic studies, this transition and the soil distribution of this surface were studied, correlating them with the different parent materials and the morphoclimatic model of landscape evolution in Southeastern Brazil. The Typic Hapludox was formed on a sandy Cenozoic deposit (Q that overlies a pellitic deposit of the Iratí formation (Pi, representing a regional erosive discordance. Westwards to the Piracicaba River, this sequence is interrupted by a diabase sill overlain by a red clayey material which gave origin to the Kandiudalfic Eutrudox. Two post-Permian depositional events were identified by the two stonelines and stratigraphical discontinuities. The first event generated the deposition of a sandy sediment in the form of levelled alveoluses on regional barriers, most of these formed by dikes and diabase sills, probably during a drier phase. The second depositional event, leading to the deposition of the red clay was probably the dissection of the previously formed pediplane during a humid climate, followed by another pedimentation process during a later, drier period.

  4. Assessment of subgrid-scale models with a large-eddy simulation-dedicated experimental database: The pulsatile impinging jet in turbulent cross-flow (United States)

    Baya Toda, Hubert; Cabrit, Olivier; Truffin, Karine; Bruneaux, Gilles; Nicoud, Franck


    Large-Eddy Simulation (LES) in complex geometries and industrial applications like piston engines, gas turbines, or aircraft engines requires the use of advanced subgrid-scale (SGS) models able to take into account the main flow features and the turbulence anisotropy. Keeping this goal in mind, this paper reports a LES-dedicated experiment of a pulsatile hot-jet impinging a flat-plate in the presence of a cold turbulent cross-flow. Unlike commonly used academic test cases, this configuration involves different flow features encountered in complex configurations: shear/rotating regions, stagnation point, wall-turbulence, and the propagation of a vortex ring along the wall. This experiment was also designed with the aim to use quantitative and nonintrusive optical diagnostics such as Particle Image Velocimetry, and to easily perform a LES involving a relatively simple geometry and well-controlled boundary conditions. Hence, two eddy-viscosity-based SGS models are investigated: the dynamic Smagorinsky model [M. Germano, U. Piomelli, P. Moin, and W. Cabot, "A dynamic subgrid-scale eddy viscosity model," Phys. Fluids A 3(7), 1760-1765 (1991)] and the σ-model [F. Nicoud, H. B. Toda, O. Cabrit, S. Bose, and J. Lee, "Using singular values to build a subgrid-scale model for large eddy simulations," Phys. Fluids 23(8), 085106 (2011)]. Both models give similar results during the first phase of the experiment. However, it was found that the dynamic Smagorinsky model could not accurately predict the vortex-ring propagation, while the σ-model provides a better agreement with the experimental measurements. Setting aside the implementation of the dynamic procedure (implemented here in its simplest form, i.e., without averaging over homogeneous directions and with clipping of negative values to ensure numerical stability), it is suggested that the mitigated predictions of the dynamic Smagorinsky model are due to the dynamic constant, which strongly depends on the mesh resolution

  5. An explicit relaxation filtering framework based upon Perona-Malik anisotropic diffusion for shock capturing and subgrid scale modeling of Burgers turbulence

    CERN Document Server

    Maulik, Romit


    In this paper, we introduce a relaxation filtering closure approach to account for subgrid scale effects in explicitly filtered large eddy simulations using the concept of anisotropic diffusion. We utilize the Perona-Malik diffusion model and demonstrate its shock capturing ability and spectral performance for solving the Burgers turbulence problem, which is a simplified prototype for more realistic turbulent flows showing the same quadratic nonlinearity. Our numerical assessments present the behavior of various diffusivity functions in conjunction with a detailed sensitivity analysis with respect to the free modeling parameters. In comparison to direct numerical simulation (DNS) and under-resolved DNS results, we find that the proposed closure model is efficient in the prevention of energy accumulation at grid cut-off and is also adept at preventing any possible spurious numerical oscillations due to shock formation under the optimal parameter choices. In contrast to other relaxation filtering approaches, it...

  6. Numerical Simulation of Atmospheric Boundary Layer Flow Over Battlefield-scale Complex Terrain: Surface Fluxes From Resolved and Subgrid Scales (United States)


    Grimmond, 2015: Proc. 9th International Conference on Urban Climate , Paris, France. Anderson W, Li Q, Bou-Zeid E, 2014: Proc. of American...represen- tative information is known about the macroscale attributes of these coher- ent motions, we have developed a sim- ple, semi -empirical model to...dust from arid landscapes on the Llano Estacado in west Texas and eastern New Mexico. • Under Review: National Science Foundation, Fluid Dynamics Program

  7. Continuity and Discontinuity in the Cultural Landscape of the Capital City: Paris and Skopje

    Directory of Open Access Journals (Sweden)

    Maciej Falski


    It appears that the most important agent in the capital landscape is the state. It is the bureaucracy of the state, appearing in the role of executor of the national will, deciding on the shape of the image of the city, reinforcing those values that seem to be desirable from the perspective of the represented group. The lack of that factor leads, as in the case of Skopje, to the preservation of the local past and/or to a haphazardly implemented publicly sponsored construction. In both cases discussed above, the map and the landmarks mirror the most important categories of national narrative. The shape of this narrative depends largely upon the central authorities of the nation. Ciągłość i nieciągłość w przestrzeni miasta stołecznego: Paryż i Skopje Przedmiotem niniejszego artykułu jest zagadnienie tworzenia wizji ciągłości dziejowej, a więc usensowionej narracji o przeszłości, w przestrzeni miasta. Miasto bowiem jawi się jako przestrzeń kulturowa par excellence i ono właśnie stwarza najlepsze możliwości wpływu na interpretację poprzez tworzenie specyficznego układu odniesień symbolicznych i obrazów, pobudzających grę interpretacji. Miasto zamieszkiwane jest przez wiele jednostek i różnorakich grup, co zmusza je do negocjacji znaczeń. Przedmiotem przedstawionych tu badań są stolice. Stolica państwa to bowiem miasto szczególne, co zazwyczaj podkreśla sam status prawny ośrodka stołecznego regulowany przez specjalną ustawę, staje się niezwykle ważną przestrzenią symboliczną, miejscem pokazu państwowej i narodowej siły, eksponowania i utwierdzania tożsamości, prezentowania wizerunku obcym oraz kształtowania pożądanego wizerunku na użytek obywateli – członków swojej grupy. Na przykładzie Paryża i Skopja, miast o odmiennej kontekstowo historii, chciałbym pokazać specyficzne dla przestrzeni miejskiej sposoby indukowania interpretacji, albowiem mimo oczywistych różnic oba miasta pozwalają dostrzec historyczny

  8. Large Eddy Simulations of a Premixed Jet Combustor Using Flamelet-Generated Manifolds: Effects of Heat Loss and Subgrid-Scale Models

    KAUST Repository

    Hernandez Perez, Francisco E.


    Large eddy simulations of a turbulent premixed jet flame in a confined chamber were conducted using the flamelet-generated manifold technique for chemistry tabulation. The configuration is characterized by an off-center nozzle having an inner diameter of 10 mm, supplying a lean methane-air mixture with an equivalence ratio of 0.71 and a mean velocity of 90 m/s, at 573 K and atmospheric pressure. Conductive heat loss is accounted for in the manifold via burner-stabilized flamelets and the subgrid-scale (SGS) turbulencechemistry interaction is modeled via presumed probability density functions. Comparisons between numerical results and measured data show that a considerable improvement in the prediction of temperature is achieved when heat losses are included in the manifold, as compared to the adiabatic one. Additional improvement in the temperature predictions is obtained by incorporating radiative heat losses. Moreover, further enhancements in the LES predictions are achieved by employing SGS models based on transport equations, such as the SGS turbulence kinetic energy equation with dynamic coefficients. While the numerical results display good agreement up to a distance of 4 nozzle diameters downstream of the nozzle exit, the results become less satisfactory along the downstream, suggesting that further improvements in the modeling are required, among which a more accurate model for the SGS variance of progress variable can be relevant.

  9. Advanced subgrid-scale modeling for convection-dominated species transport at fluid interfaces with application to mass transfer from rising bubbles (United States)

    Weiner, Andre; Bothe, Dieter


    This paper presents a novel subgrid scale (SGS) model for simulating convection-dominated species transport at deformable fluid interfaces. One possible application is the Direct Numerical Simulation (DNS) of mass transfer from rising bubbles. The transport of a dissolving gas along the bubble-liquid interface is determined by two transport phenomena: convection in streamwise direction and diffusion in interface normal direction. The convective transport for technical bubble sizes is several orders of magnitude higher, leading to a thin concentration boundary layer around the bubble. A true DNS, fully resolving hydrodynamic and mass transfer length scales results in infeasible computational costs. Our approach is therefore a DNS of the flow field combined with a SGS model to compute the mass transfer between bubble and liquid. An appropriate model-function is used to compute the numerical fluxes on all cell faces of an interface cell. This allows to predict the mass transfer correctly even if the concentration boundary layer is fully contained in a single cell layer around the interface. We show that the SGS-model reduces the resolution requirements at the interface by a factor of ten and more. The integral flux correction is also applicable to other thin boundary layer problems. Two flow regimes are investigated to validate the model. A semi-analytical solution for creeping flow is used to assess local and global mass transfer quantities. For higher Reynolds numbers ranging from Re = 100 to Re = 460 and Péclet numbers between Pe =104 and Pe = 4 ṡ106 we compare the global Sherwood number against correlations from literature. In terms of accuracy, the predicted mass transfer never deviates more than 4% from the reference values.

  10. Impact of an additional radiative CO2 cooling induced by subgrid-scale gravity waves in the middle and upper atmosphere (United States)

    Medvedev, A. S.; Yigit, E.; Kutepov, A.; Feofilov, A.


    Atmospheric fluctuations produced by GWs are a substantial source of momentum and energy in the thermosphere (Yigit et al., 2009). These fluctuations also affect radiative transfer and, ultimately, the radiative heating/cooling rates. Recently, Kutepov et al. (2007) developed a methodology to account for radiative effects of subgrid-scale GWs not captured by general circulation models (GCMs). It has been extended by Kutepov et al (2011) to account not only for wave-induced variations of temperature, but also of CO2 and atomic oxygen. It was shown that these GWs can cause additional cooling of up to 3 K/day around mesopause. A key parameter for calculating the additional cooling is the temperature variance associated with GWs, which is a subproduct of conventional GW schemes. In this study, the parameterization of Kutepov et al. (2011) has been implemented into a 3-D comprehensive GCM that incorporates the effects of unresolved GWs via the extended nonlinear scheme of Yigit et al. (2008). Simulated net effects of the additional radiative CO2 cooling on the temperature and wind in the mesosphere and lower thermosphere are presented and discussed for solstice conditions. 1. Kutepov, A. A, A. G. Feofilov, A. S. Medvedev, A. W. A. Pauldrach, and P. Hartogh (2007), Geophys. Res. Lett. 34, L24807, doi:10.1029/2007GL032392. 2. Kutepov, A. A., A. G. Feofilov, A. S. Medvedev, U. Berger, and M. Kaufmann (2011), submitted to Geophys. Res. Letts. 3. Yigit, E., A. D. Aylward, and A. S. Medvedev (2008), J. Geophys. Res., 113, D19106, doi:10.1029/2008JD010135. 4. Yigit, E., A. S. Medvedev, A. D. Aylward, P. Hartogh, and M. J. Harris (2009), J. Geophys. Res., 114, D07101, doi:10.1029/2008JD011132.

  11. Intercomparison of different subgrid-scale models for the Large Eddy Simulation of the diurnal evolution of the atmospheric boundary layer during the Wangara experiment (United States)

    Dall'Ozzo, C.; Carissimo, B.; Musson-Genon, L.; Dupont, E.; Milliez, M.


    The study of a whole diurnal cycle of the atmospheric boundary layer evolving through unstable, neutral and stable states is essential to test a model applicable to the dispersion of pollutants. Consequently a LES of a diurnal cycle is performed and compared to observations from the Wangara experiment (Day 33-34). All simulations are done with Code_Saturne [1] an open source CFD code. The synthetic eddy method (SEM) [2] is implemented to initialize turbulence at the beginning of the simulation. Two different subgrid-scale (SGS) models are tested: the Smagorinsky model [3],[4] and the dynamical Wong and Lilly model [5]. The first one, the most classical, uses a Smagorinsky constant Cs to parameterize the dynamical turbulent viscosity while the second one relies on a variable C. Cs remains insensitive to the atmospheric stability level in contrary to the parameter C determined by the Wong and Lilly model. It is based on the error minimization of the difference between the tensors of the resolved turbulent stress (Lij) and the difference of the SGS stress tensors at two different filter scales (Mij). Furthermore, the thermal eddy diffusivity, as opposed to the Smagorinsky model, is calculated with a dynamical Prandtl number determination. The results are confronted to previous simulations from Basu et al. (2008) [6], using a locally averaged scale-dependent dynamic (LASDD) SGS model, and to previous RANS simulations. The accuracy in reproducing the experimental atmospheric conditions is discussed, especially regarding the night time low-level jet formation. In addition, the benefit of the utilization of a coupled radiative model is discussed.

  12. Early discontinuation

    DEFF Research Database (Denmark)

    Hansen, Dorte Gilså; Felde, Lina; Gichangi, Anthony


    Introduction Discontinuation of medical drug treatment is a serious problem in primary care. The need for a better understanding of the processes, including physician-specific mechanisms, is apparent. The aim of this study was to analyse the association between general practitioners' prescribing....... There was a positive association between the prevalence of prescribing for the specific drugs studied (antidepressants, antidiabetics, drugs against osteoporosis and lipid-lowering drugs) and early discontinuation (r = 0.29 -0.44), but not for anti-hypertensive drugs. The analysis of the association between prevalence...... of all drugs and drug-specific early discontinuation showed some degree of positive association - strongest for anti-hypertensive drugs (r = 0.62) and antidepressants (r = 0.43). Conclusion This study confirmed our hypothesis that general practitioners with high levels of prescribing attain higher rates...

  13. Organising medication discontinuation

    DEFF Research Database (Denmark)

    Nixon, Michael; Kousgaard, Marius Brostrøm


    Background: Discontinuing medications is a complex decision making process and an important medical practice. It is a tool in reducing polypharmacy, reducing health system expenditure and improving patient quality of life. Few studies have looked at how general practitioners (GPs) discontinue...... a medication, in agreement with the patients, from a professional perspective. Three research questions were examined in this study: when does medication discontinuation occur in general practice, how is discontinuing medication handled in the GP’s practice and how do GPs make decisions about discontinuing...... medication? Methods: Twenty four GPs were interviewed using a maximum variation sample strategy. Participant observations were done in three general practices, for one day each, totalling approximately 30 consultations. Results: The results show that different discontinuation cues (related to the type...

  14. Excursions in fluvial (dis)continuity (United States)

    Grant, Gordon E.; O'Connor, James E.; Safran, Elizabeth


    Lurking below the twin concepts of connectivity and disconnectivity are their first, and in some ways, richer cousins: continuity and discontinuity. In this paper we explore how continuity and discontinuity represent fundamental and complementary perspectives in fluvial geomorphology, and how these perspectives inform and underlie our conceptions of connectivity in landscapes and rivers. We examine the historical roots of continuum and discontinuum thinking, and how much of our understanding of geomorphology rests on contrasting views of continuity and discontinuity. By continuum thinking we refer to a conception of geomorphic processes as well as geomorphic features that are expressed along continuous gradients without abrupt changes, transitions, or thresholds. Balance of forces, graded streams, and hydraulic geometry are all examples of this perspective. The continuum view has played a prominent role in diverse disciplinary fields, including ecology, paleontology, and evolutionary biology, in large part because it allows us to treat complex phenomena as orderly progressions and invoke or assume equilibrium processes that introduce order and prediction into our sciences.In contrast the discontinuous view is a distinct though complementary conceptual framework that incorporates non-uniform, non-progressive, and non-equilibrium thinking into understanding geomorphic processes and landscapes. We distinguish and discuss examples of three different ways in which discontinuous thinking can be expressed: 1) discontinuous spatial arrangements or singular events; 2) specific process domains generally associated with thresholds, either intrinsic or extrinsic; and 3) physical dynamics or changes in state, again often threshold-linked. In moving beyond the continuous perspective, a fertile set of ideas comes into focus: thresholds, non-equilibrium states, heterogeneity, catastrophe. The range of phenomena that is thereby opened up to scientific exploration similarly expands

  15. The Lehmann discontinuity


    Anderson, D. L.; Bolt, B. A.; Morse, S. A.


    Recent reflections by Inge Lehmann on her discovery of the inner core (Eos, January 20, 1987, p. 33; see also Bolt [1987, 1982]) remind us that this outstanding Earth scientist is now in her 100th year. The inner core boundary (ICB) is one of the three great seismic-compositional discontinuities that divide Earth into crust, mantle, core, and inner core. The other two discontinuities are well known by names honoring their discoverers, Andrija Mohorovicic and Beno Gutenberg. In this tradition,...

  16. Free discontinuity problems

    CERN Document Server

    Pratelli, Aldo


    This book presents a series of lectures on three of the best known examples of free discontinuity problems: the Mumford-Shah model for image segmentation, a variational model for the epitaxial growth of thin films, and the sharp interface limit of the Ohta-Kawasaki model for pattern formation in dyblock copolymers.

  17. Modern Regression Discontinuity Analysis (United States)

    Bloom, Howard S.


    This article provides a detailed discussion of the theory and practice of modern regression discontinuity (RD) analysis for estimating the effects of interventions or treatments. Part 1 briefly chronicles the history of RD analysis and summarizes its past applications. Part 2 explains how in theory an RD analysis can identify an average effect of…

  18. [Drug discontinuation in depression]. (United States)

    Vanelle, J M; Féline, A


    Before stopping or starting medications in depression, the first step is a through assessment of the patient's mood disorder: past medical general and psychiatric history, psychological profile, past specific treatment history... Today some data are well demonstrated: antidepressant or lithium or carbamazepine discontinuation should be done gradually (over weeks or months) and with an intensive medical follow-up; after the acute treatment of the index depressive episode, a full therapeutic dose of the antidepressant agent should be continued for at least 4 to 6 months; antipsychotic drugs and minor tranquilizers use should be limited: combination of a neuroleptic and an antidepressant in depression with psychotic features, combination of a minor tranquilizer in depression with anxiety during the first three weeks if necessary. A contario the timing and the method of discontinuing maintenance treatment (lithium or antidepressant) have not been well studied. Literature data are discussed: frequency of recurrence during treatment discontinuation, even after long-term euthymia; possible risk for developing rapid-cycles or non response after lithium discontinuation. More precise clinical guidelines are necessary.

  19. Hamiltonian systems with discontinuities


    Tulczyjew, Wlodzimierz M.


    Standandard Hamiltonian mechanics in its homogeneous formulation is applied to the study of discontinuities representing rapid changes of Hamiltonians. Different formulations of Hamiltonian mechanics are reviewed. An original representation of a positive homogeneous Hamiltonian system by an outer oriented coisotropic submanifold of the phase space is proposed.

  20. Error-landscape-based multiobjective calibration of the Smagorinsky eddy-viscosity using high-Reynolds-number decaying turbulence data (United States)

    Meyers, Johan; Meneveau, Charles; Geurts, Bernard J.


    A suite of large-eddy simulations (LESs) of decaying homogeneous isotropic turbulence at high Reynolds numbers is performed and compared to wind-tunnel experiments in the tradition of Comte-Bellot and Corrsin. The error-landscape approach is used for the evaluation of the Smagorinsky model, and the results are used to identify an optimal combination of model parameter and resolution in a statistically robust fashion. The use of experimental reference data in the error-landscape approach allows to evaluate the optimal Smagorinsky coefficient at high Reynolds numbers and to perform detailed comparisons with analytical predictions. We demonstrate, using a pseudospectral discretization, that the optimal so-called Smagorinsky trajectory obtained from the error-landscape analysis converges at high simulation resolutions to the high-Re theoretical Lilly prediction for the Smagorinsky coefficient. Using modified wavenumbers in the same spectral code, the current study also presents error-landscape results based on LES with "second-order" discretization errors. By slightly revising Lilly's analysis, we show that including the effect of numerical discretization when evaluating the strain-rate tensor needed in the subgrid-scale model leads to a good prediction of the optimal Smagorinsky parameter obtained from the corresponding error-landscape. Using similar analytical tools, we further demonstrate that the dynamic procedure can also be adapted to better account for the effects of discretization and test-filter shape.


    Directory of Open Access Journals (Sweden)



    Full Text Available Gaston Bachelard’s position toward the philosophy of Henri Bergson is most interesting. In La Dialectique de la durée (1936, Bachelard claims that “of Bergsonism we accept everything but continuity” and that the rest of his book will be an attempt to show the possibility of a “discontinuous Bergsonism”. In this paper, I focus on the reaction of Bachelard to works of Bergson such as the Essai sur les données immédiates de la conscience (1889, L’Evolution créatrice (1907, and Durée et simultanéité: à propos de la théorie d’Einstein (1922 and demonstrate that even though the conditions necessary for the possibility of a discontinuous Bergsonism are not the same ones which Bachelard had in mind when he accepted most of Bergsonism, their phenomenologies of the scientific spirit were analogous.

  2. Explicit filtering in large eddy simulation using a discontinuous Galerkin method (United States)

    Brazell, Matthew J.

    The discontinuous Galerkin (DG) method is a formulation of the finite element method (FEM). DG provides the ability for a high order of accuracy in complex geometries, and allows for highly efficient parallelization algorithms. These attributes make the DG method attractive for solving the Navier-Stokes equations for large eddy simulation (LES). The main goal of this work is to investigate the feasibility of adopting an explicit filter in the numerical solution of the Navier-Stokes equations with DG. Explicit filtering has been shown to increase the numerical stability of under-resolved simulations and is needed for LES with dynamic sub-grid scale (SGS) models. The explicit filter takes advantage of DG's framework where the solution is approximated using a polyno- mial basis where the higher modes of the solution correspond to a higher order polynomial basis. By removing high order modes, the filtered solution contains low order frequency content much like an explicit low pass filter. The explicit filter implementation is tested on a simple 1-D solver with an initial condi- tion that has some similarity to turbulent flows. The explicit filter does restrict the resolution as well as remove accumulated energy in the higher modes from aliasing. However, the ex- plicit filter is unable to remove numerical errors causing numerical dissipation. A second test case solves the 3-D Navier-Stokes equations of the Taylor-Green vortex flow (TGV). The TGV is useful for SGS model testing because it is initially laminar and transitions into a fully turbulent flow. The SGS models investigated include the constant coefficient Smagorinsky model, dynamic Smagorinsky model, and dynamic Heinz model. The constant coefficient Smagorinsky model is over dissipative, this is generally not desirable however it does add stability. The dynamic Smagorinsky model generally performs better, especially during the laminar-turbulent transition region as expected. The dynamic Heinz model which is

  3. System dynamics with interaction discontinuity

    CERN Document Server

    Luo, Albert C J


    This book describes system dynamics with discontinuity caused by system interactions and presents the theory of flow singularity and switchability at the boundary in discontinuous dynamical systems. Based on such a theory, the authors address dynamics and motion mechanism of engineering discontinuous systems due to interaction. Stability and bifurcations of fixed points in nonlinear discrete dynamical systems are presented, and mapping dynamics are developed for analytical predictions of periodic motions in engineering discontinuous dynamical systems. Ultimately, the book provides an alternative way to discuss the periodic and chaotic behaviors in discontinuous dynamical systems.

  4. Landscape Studio

    DEFF Research Database (Denmark)

    Hansen, Peter Lundsgaard


    Landscape studio documents is the biography of the method 'design conversation' and contributes to the way we work with landscapes. The blog communicates renewed landscape didactics and leads to the innovation of design practices.......Landscape studio documents is the biography of the method 'design conversation' and contributes to the way we work with landscapes. The blog communicates renewed landscape didactics and leads to the innovation of design practices....

  5. Benzodiazepine dependence: management of discontinuation. (United States)

    Rickels, K; Case, W G; Schweizer, E; Garcia-Espana, F; Fridman, R


    This article discusses the management of benzodiazepine (BZ) withdrawal in patients who are chronically benzodiazepine dependent. Gradual benzodiazepine discontinuation is preferable to abrupt discontinuation, particularly for patients on short half-life benzodiazepines. For a small number of patients, replacement of short half-life with long half-life benzodiazepines may also be helpful. Finally, we present new preliminary data from a controlled, double-blind study that suggest that adjunctive use of such drugs as carbamazepine, imipramine, and buspirone may be helpful in managing gradual benzodiazepine discontinuation. Initiating adjunctive medication prior to, and continuing it during and after benzodiazepine discontinuation led to significantly higher discontinuation success rates for carbamazepine (91%), buspirone (85%), and imipramine (79%) than for placebo (58%) (p less than .05). Careful followup for an extended period of time is needed after benzodiazepine discontinuation because, frequently, emerging psychiatric symptoms may again necessitate psychiatric intervention.

  6. Testing discontinuities in nonparametric regression

    KAUST Repository

    Dai, Wenlin


    In nonparametric regression, it is often needed to detect whether there are jump discontinuities in the mean function. In this paper, we revisit the difference-based method in [13 H.-G. Müller and U. Stadtmüller, Discontinuous versus smooth regression, Ann. Stat. 27 (1999), pp. 299–337. doi: 10.1214/aos/1018031100


    Directory of Open Access Journals (Sweden)

    Silviu COSTACHIE


    Full Text Available This paper analyzes the evolution of rural tourism since the early '70s, the time of onset, and indicates the discontinuity recorded especially after 1989 until the brink of the preparation for Romania's joining the European Union and the present state, one far behind the countries with extremely high degree of urbanization and industrialization, probably as a result of a lack of strategy for this form of tourism in which the beneficiary is the Ministry of Tourism, as the health tourism and ecotourism have recently had. The location of many villages in areas of outstanding natural landscapes, the richness and variety of cultural heritage that endows them, are issues related to an increased tourism potential that can be capitalized and those unique tourism products that can not be seen, admired and offered by other countries.

  8. Threshold loss of discontinuous permafrost and landscape evolution. (United States)

    Chasmer, Laura; Hopkinson, Chris


    This study demonstrates linkages between the 1997/1998 El Niño/Southern Oscillation index and a threshold shift to increased permafrost loss within a southern Taiga Plains watershed, Northwest Territories, Canada. Three-dimensional contraction of permafrost plateaus and changes in vegetation structural characteristics are determined from multitemporal airborne Light Detection And Ranging (LiDAR) surveys in 2008, 2011 and 2015. Morphological changes in permafrost cover are compared with optical image analogues from 1970, 1977, 2000 and 2008 and time-series hydro-climate data. Results demonstrate that significant changes in air temperature, precipitation, runoff and a shortening of the snow-covered season by 35 days (1998-2014) and 50 days (1998 only) occurred after 1997. The albedo reduction associated with 35 and 50 days less snow cover leads to increases in shortwave energy receipt during the active thaw period of ~12% (3% annually) and ~16% (5% annually), respectively. From 2000 to 2015, sporadic permafrost loss accelerated from 0.19% (of total basin area) per year between 1970 and 2000 to 0.58% per year from 2000 to 2015, with a projected total loss of permafrost by ~2044. From ~1997 to 2011, we observe a corresponding shift to increased runoff ratio. However, observed increases in the proportion of snow precipitation and the volumetric contribution of permafrost loss to runoff post-1997 (0.6-6.4% per year) cannot fully explain this shift. This suggests increases in drainage efficiency and possible losses from long-term groundwater storage as a result of subtle terrain morphological and soil zone hydraulic conductivity changes. These hydrological changes appear coincident with high vegetation mortality at plateau margins combined with succession-related canopy growth in some bog and fen areas, which are presumed to be drying. Similar changes in runoff response were observed at adjacent Birch, Trout and Jean Marie River watersheds indicating that observations are representative of northern Boreal sporadic permafrost/wetland watersheds in the Taiga Plains. © 2016 John Wiley & Sons Ltd.

  9. Landscape Ecology

    DEFF Research Database (Denmark)

    Christensen, Andreas Aagaard; Brandt, Jesper; Svenningsen, Stig Roar


    Landscape ecology is an interdisciplinary field of research and practice that deals with the mutual association between the spatial configuration and ecological functioning of landscapes, exploring and describing processes involved in the differentiation of spaces within landscapes......, and the ecological significance of the patterns which are generated by such processes. In landscape ecology, perspectives drawn from existing academic disciplines are integrated based on a common, spatially explicit mode of analysis developed from classical holistic geography, emphasizing spatial and landscape...... pattern analysis and ecological interaction of land units. The landscape is seen as a holon: an assemblage of interrelated phenomena, both cultural and biophysical, that together form a complex whole. Enduring challenges to landscape ecology include the need to develop a systematic approach able...

  10. Landscape relatedness

    DEFF Research Database (Denmark)

    Norman, Anita J; Strønen, Astrid Vik; Fuglstad, Geir-Arne


    Context Methods for detecting contemporary, fine-scale population genetic structure in continuous populations are scarce. Yet such methods are vital for ecological and conservation studies, particularly under a changing landscape. Objectives Here we present a novel, spatially explicit method...... that we call landscape relatedness (LandRel). With this method, we aim to detect contemporary, fine-scale population structure that is sensitive to spatial and temporal changes in the landscape. Methods We interpolate spatially determined relatedness values based on SNP genotypes across the landscape...

  11. Management applications of discontinuity theory (United States)

    Angeler, David G.; Allen, Craig R.; Barichievy, Chris; Eason, Tarsha; Garmestani, Ahjond S.; Graham, Nicholas A.J.; Granholm, Dean; Gunderson, Lance H.; Knutson, Melinda; Nash, Kirsty L.; Nelson, R. John; Nystrom, Magnus; Spanbauer, Trisha; Stow, Craig A.; Sundstrom, Shana M.


    Human impacts on the environment are multifaceted and can occur across distinct spatiotemporal scales. Ecological responses to environmental change are therefore difficult to predict, and entail large degrees of uncertainty. Such uncertainty requires robust tools for management to sustain ecosystem goods and services and maintain resilient ecosystems.We propose an approach based on discontinuity theory that accounts for patterns and processes at distinct spatial and temporal scales, an inherent property of ecological systems. Discontinuity theory has not been applied in natural resource management and could therefore improve ecosystem management because it explicitly accounts for ecological complexity.Synthesis and applications. We highlight the application of discontinuity approaches for meeting management goals. Specifically, discontinuity approaches have significant potential to measure and thus understand the resilience of ecosystems, to objectively identify critical scales of space and time in ecological systems at which human impact might be most severe, to provide warning indicators of regime change, to help predict and understand biological invasions and extinctions and to focus monitoring efforts. Discontinuity theory can complement current approaches, providing a broader paradigm for ecological management and conservation.

  12. Nordic Landscape

    DEFF Research Database (Denmark)

    Hjortshøj, Rasmus


    This Box Set NORDIC LANDSCAPE presents Nordic Territories, a project by Rasmus Hjortshøj, exploring the man-made landscapes of the coastal territories and the entanglement of society and nature in times where it is no longer merely mankind subjected to nature, but where nature is equally being...

  13. Industrious Landscaping

    DEFF Research Database (Denmark)

    Brichet, Nathalia Sofie; Hastrup, Frida


    This article offers a history of landscaping at Søby brown coal beds – a former mining site in western Denmark. Exploring this industrial landscape through a series of projects that have made different natural resources appear, we argue that what is even recognized as resources shifts over time...... according to radically different and unpredictable agendas. Natural resources emerge as feats of particular political and historical landscape configurations, rather than fixed dormant sediments waiting to be exploited. This indicates that the Søby landscape is fundamentally volatile, as its resourcefulness...... has been seen interchangeably to rest with brown coal business, inexpensive estates for do-it-yourself people, pasture for grazing, and recreational forest, among other things. We discuss these rifts in landscaping, motivated by what we refer to as industriousness, to show that in an industrial site...

  14. Industrious Landscaping

    DEFF Research Database (Denmark)

    Brichet, Nathalia Sofie; Hastrup, Frida


    has been seen interchangeably to rest with brown coal business, inexpensive estates for do-it-yourself people, pasture for grazing, and recreational forest, among other things. We discuss these rifts in landscaping, motivated by what we refer to as industriousness, to show that in an industrial site...... analysis of shifting landscape projects and has an essential methodological corollary, namely that fieldwork must be improvisational, situated, and humble. Rather than finding the ‘right’ field materials for a canonical landscape history of Søby, we develop a method of ‘dustballing’ – being blown here...

  15. Fitness in animals correlates with proximity to discontinuities in body mass distributions. (United States)

    Angeler, David G.; Allen, Craig R.; Vila-Gispert, Anna; Almeida, David


    Discontinuous structure in landscapes may cause discontinuous, aggregated species body-mass patterns, reflecting the scales of structure available to animal communities within a landscape. Empirical analyses have shown that the location of species within body mass aggregations, which reflect this scale-specific organization, is non-random with regard to several ecological phenomena, including species extinctions. The propensity of declining species to have body masses proximate to discontinuities suggests that transition zones between scaling regimes ultimately decreases the ecological fitness for some species. We test this proposition using vulnerable and unthreatened fish species in Mediterranean streams with differing levels of human impact. We show that the proximity to discontinuities in body mass aggregations (“distance-to-edge”) of more vs. less fit individuals within vulnerable and unthreatened populations differs. Specifically, regression analysis between the scaled mass index, a proxy of animal fitness, and distance-to-edge reveals negative and positive relationships for vulnerable and unthreatened species, respectively. That is, fitness is higher close to discontinuities in vulnerable populations and toward the center of body mass aggregation groups in unthreatened populations. Our results demonstrate the suitability of the discontinuity framework for scrutinizing non-random patterns of environmental impact in populations. Further exploration of the usefulness of this method across other ecosystems and organism groups is warranted.

  16. A Dynamic Eddy Viscosity Model for the Shallow Water Equations Solved by Spectral Element and Discontinuous Galerkin Methods (United States)

    Marras, Simone; Suckale, Jenny; Giraldo, Francis X.; Constantinescu, Emil


    We present the solution of the viscous shallow water equations where viscosity is built as a residual-based subgrid scale model originally designed for large eddy simulation of compressible [1] and stratified flows [2]. The necessity of viscosity for a shallow water model not only finds motivation from mathematical analysis [3], but is supported by physical reasoning as can be seen by an analysis of the energetics of the solution. We simulated the flow of an idealized wave as it hits a set of obstacles. The kinetic energy spectrum of this flow shows that, although the inviscid Galerkin solutions -by spectral elements and discontinuous Galerkin [4]- preserve numerical stability in spite of the spurious oscillations in the proximity of the wave fronts, the slope of the energy cascade deviates from the theoretically expected values. We show that only a sufficiently small amount of dynamically adaptive viscosity removes the unwanted high-frequency modes while preserving the overall sharpness of the solution. In addition, it yields a physically plausible energy decay. This work is motivated by a larger interest in the application of a shallow water model to the solution of tsunami triggered coastal flows. In particular, coastal flows in regions around the world where coastal parks made of mitigation hills of different sizes and configurations are considered as a means to deviate the power of the incoming wave. References [1] M. Nazarov and J. Hoffman (2013) "Residual-based artificial viscosity for simulation of turbulent compressible flow using adaptive finite element methods" Int. J. Numer. Methods Fluids, 71:339-357 [2] S. Marras, M. Nazarov, F. X. Giraldo (2015) "Stabilized high-order Galerkin methods based on a parameter-free dynamic SGS model for LES" J. Comput. Phys. 301:77-101 [3] J. F. Gerbeau and B. Perthame (2001) "Derivation of the viscous Saint-Venant system for laminar shallow water; numerical validation" Discrete Contin. Dyn. Syst. Ser. B, 1:89?102 [4] F

  17. Electromagnetic Landscape

    DEFF Research Database (Denmark)

    Cermak, Daniel; Okutsu, Ayaka; Jørgensen, Stina Marie Hasse


    Daniel Cermak-Sassenrath, Ayaka Okutsu, Stina Hasse. Electromagnetic Landscape - In-between Signal, Noise and Environment. Installation and artist talk. 21th International Symposium on Electronic Art (ISEA) 2015, Vancouver, CAN, Aug 14-18, 2015.......Daniel Cermak-Sassenrath, Ayaka Okutsu, Stina Hasse. Electromagnetic Landscape - In-between Signal, Noise and Environment. Installation and artist talk. 21th International Symposium on Electronic Art (ISEA) 2015, Vancouver, CAN, Aug 14-18, 2015....

  18. A generalized discrete strong discontinuity approach

    NARCIS (Netherlands)

    Dias-da-Costa, D.; Alfaiate, J.; Sluys, L.J.; Julio, E.


    Several local embedded discontinuity formulations have already been developed, in which constant strain triangles and constant jumps are adopted. However, these formulations lead to jump and traction discontinuity across element boundaries and stress locking effects. Herein, a new contribution to

  19. Strategies for discontinuation of proton pump inhibitors

    DEFF Research Database (Denmark)

    Haastrup, Peter; Paulsen, Maja S; Begtrup, Luise M


    and ongoing studies. A total of 371 abstracts were scrutinized to determine relevancy. RESULTS: The thorough search resulted in six clinical studies on strategies for discontinuation of PPIs. All discontinuation regimens used in the studies differed, and several interventions have been tested in order...... to decrease use of PPIs. Discontinuations were reported across all studies ranging from 14% to 64% without deteriorating symptom control. Tapering seems to be a more effective discontinuation strategy than abrupt discontinuation. CONCLUSION: Discontinuation of PPIs is feasible in a clinical setting......PURPOSE: Proton pump inhibitors (PPIs) are considered to be overprescribed. Consensus on how to attempt discontinuation is, however, lacking. We therefore conducted a systematic review of clinical studies on discontinuation of PPIs. METHODS: Systematic review based on clinical studies investigating...

  20. Factors affecting IUCD discontinuation in Nepal

    DEFF Research Database (Denmark)

    Thapa, Subash; Paudel, Ishwari Sharma; Bhattarai, Sailesh


    Information related to contraception discontinuation, especially in the context of Nepal is very limited. A nested case-control study was carried out to determine the factors affecting discontinuation of intrauterine contraceptive devices (IUCDs). A total of 115 cases (IUCD discontinuers) and 115...

  1. Farmers\\' Discontinuance Decision Behaviours Of Yam Minisett ...

    African Journals Online (AJOL)

    Farmers' discontinuance decision behaviours of technologies is attributed to certain reasons and it is governed by certain socio-economic variables. This study identified and analyzed the rate of discontinuance of yam minisett technology, reasons for discontinuance and the socio-economic determinants of the ...

  2. Recent Developments on Discontinuous Precipitation

    Directory of Open Access Journals (Sweden)

    Zięba P.


    Full Text Available The discontinuous precipitation (DP belongs to a group of diffusive solid state phase transformations during which the formation of a new phase is heterogeneous and limited to a migrating reaction front (RF. The use of analytical electron microscopy provided reliable information that there is no differences in the diffusion rate at the stationary grain boundary and moving RF of DP reaction. On the other hand, the use of “in situ” transmission electron microscopy observations indicated the importance of stop-go motion or oscillatory movement of the RF.

  3. Electromagnetic Landscape

    DEFF Research Database (Denmark)

    Cermak, Daniel; Okutsu, Ayaka; Hasse, Stina


    Electromagnetic Landscape demonstrates in direct, tangible and immediate ways effects of the disruption of the familiar. An ubiquitous technological medium, FM radio, is turned into an alien and unfamiliar one. Audience participation, the environment, radio signals and noise create a site...

  4. General practitioners’ decisions about discontinuation of medication

    DEFF Research Database (Denmark)

    Nixon, Michael Simon; Vendelø, Morten Thanning


    Purpose – The purpose of this paper is to investigate how general practitioners’ (GPs) decisions about discontinuation of medication are influenced by their institutional context. Design/methodology/approach – In total, 24 GPs were interviewed, three practices were observed and documents were...... collected. The Gioia methodology was used to analyse data, drawing on a theoretical framework that integrate the sensemaking perspective and institutional theory. Findings – Most GPs, who actively consider discontinuation, are reluctant to discontinue medication, because the safest course of action for GPs...... is to continue prescriptions, rather than discontinue them. The authors conclude that this is in part due to the ambiguity about the appropriateness of discontinuing medication, experienced by the GPs, and in part because the clinical guidelines do not encourage discontinuation of medication, as they offer GPs...

  5. Discontinuation of Preventive Drugs in General Practice

    DEFF Research Database (Denmark)

    Andersen, John Sahl; Lindberg, Laura Maria Glahder; Nixon, Michael Simon

    the most preventive drugs are prescribed in general practice. Special considerations exist in relation to medication of elderly patients. The prevalence of polypharmacy and the subsequent increased risk of side effects and drug interactions is high. Drug-related problems represent the fifth leading cause...... of preventive drugs. Qualitative interviews with patients experiencing discontinuation of preventive drugs addressing: Which attitudes do the patients have towards preventive drugs? Which thoughts do the patients have in relation to discontinuation of the drugs? How do they understand their own and the GP......’s role in the process of discontinuation? 2. Doctors’ views upon discontinuation of preventive drugs. Qualitative interviews with GPs and register studies addressing: How do GPs understand discontinuation of preventive medicine as a concept? What do GPs perceive to be the barriers to discontinuation...

  6. Contemporary Danish landscape research

    DEFF Research Database (Denmark)

    Vejre, Henrik; Brandt, Jesper


    Danish landscape research blossomed during the 1990’ies thanks to several transdisciplinary research programmes involving several institutions. The main themes of the programmes encompassed Landscape change, landscape and biological diversity, nature and landscape management, use and monitoring o...... of the countryside. The values of the Danish landscape pertain mainly to the coastal landscapes. The threats include the industrilization of the agricultural landsclaes and,in places urban sprawl.......Danish landscape research blossomed during the 1990’ies thanks to several transdisciplinary research programmes involving several institutions. The main themes of the programmes encompassed Landscape change, landscape and biological diversity, nature and landscape management, use and monitoring...

  7. Withdrawal symptoms after gabapentin discontinuation. (United States)

    Hellwig, Thaddaus R; Hammerquist, Rhonda; Termaat, Jill


    A case of apparent gabapentin withdrawal symptoms after discontinuation of gabapentin therapy is reported. A 53-year-old woman had coffee ground emesis, a two-day history of black tarry stools, and abdominal pain. The patient did have an elevated ethanol concentration (323 mg/dL), with the last reported ingestion of ethanol about 12 hours before admission. Her medical history included liver cirrhosis secondary to ethanol abuse, ascites, portal hypertension, esophageal varices (with previous band ligation three weeks prior), anemia, gastroesophageal reflux disease, neuropathic pain, and depression. Her home medications included spironolactone, nadolol, lactulose, ursodiol, ferrous sulfate, omeprazole, gabapentin, citalopram, and trazodone. She was admitted to the intensive care unit, and upper gastrointestinal endoscopy was performed, with 12 band ligations applied. After the procedure, she ingested nothing orally, including home medications, for the first two days. On day 3 of hospitalization, she developed restlessness, disorientation, confusion, agitation, and anxiety. She was presumed to be suffering from ethanol withdrawal and was treated with benzodiazepines but had no improvement in symptoms. During days 4 and 5, the patient became increasingly confused, agitated, and anxious, with complaints of headache, light sensitivity, and increasing nervousness. On day 5, gabapentin was reinitiated, and the patient's confusion and agitation improved that evening. The next morning, the patient was calm, alert, and cooperative. Her symptoms resolved, and she was discharged on hospital day 7. A patient developed apparent withdrawal symptoms beginning two days after gabapentin therapy was discontinued. The symptoms were unresponsive to treatment with benzodiazepines but completely resolved with the reinitiation of gabapentin therapy.

  8. Ezogabine skin discoloration is reversible after discontinuation. (United States)

    Mathias, Sally V; Abou-Khalil, Bassel W


    There is concern that bluish skin discoloration associated with ezogabine treatment could be permanent. We present a case of ezogabine-induced skin discoloration that resolved completely after discontinuation. A 55-year-old woman started ezogabine 400 mg three times a day at age 41. Bluish pigmentation over the toe nails, finger nails, around eyes and over and around lips was first noted after 5 years of treatment. Ezogabine was discontinued eight years after initiation. Skin discoloration improved within 6 months and completely resolved within 6 years of discontinuation. This case suggests that ezogabine-induced discoloration is reversible after discontinuation of treatment.

  9. Organising medication discontinuation: a qualitative study exploring the views of general practitioners toward discontinuing statins. (United States)

    Nixon, Michael; Kousgaard, Marius Brostrøm


    Discontinuing medications is a complex decision making process and an important medical practice. It is a tool in reducing polypharmacy, reducing health system expenditure and improving patient quality of life. Few studies have looked at how general practitioners (GPs) discontinue a medication, in agreement with the patients, from a professional perspective. Three research questions were examined in this study: when does medication discontinuation occur in general practice, how is discontinuing medication handled in the GP's practice and how do GPs make decisions about discontinuing medication? Twenty four GPs were interviewed using a maximum variation sample strategy. Participant observations were done in three general practices, for one day each, totalling approximately 30 consultations. The results show that different discontinuation cues (related to the type of consultation, medical records and the patient) create situations of dissonance that can lead to the GP considering the option of discontinuation. We also show that there is a lot of ambiguity in situations of discontinuing and that some GPs trialled discontinuing as means of generating more information that could be used to deal with the ambiguity. We conclude that the practice of discontinuation should be conceptualised as a continually evaluative process and one that requires sustained reflection through a culture of systematically scheduled check-ups, routinely eliciting the patient's experience of taking drugs and trialling discontinuation. Some policy recommendations are offered including supporting GPs with lists or handbooks that directly address discontinuation and by developing more person centred clinical guidelines that discuss discontinuation more explicitly.

  10. Fire Regime along Latitudinal Gradients of Continuous to Discontinuous Coniferous Boreal Forests in Eastern Canada


    Jeanne Portier; Sylvie Gauthier; Alain Leduc; Dominique Arseneault; Yves Bergeron


    Fire is the main disturbance in North American coniferous boreal forests. In Northern Quebec, Canada, where forest management is not allowed, the landscape is gradually constituted of more opened lichen woodlands. Those forests are discontinuous and show a low regeneration potential resulting from the cumulative effects of harsh climatic conditions and very short fire intervals. In a climate change context, and because the forest industry is interested in opening new territories to forest man...

  11. [Review on landscape heterogeneity]. (United States)

    Zhao, Yutao; Yu, Xinxiao; Guang, Wenbin


    On the base of precedent studies, the occurring mechanism, classification, measurement methods, and the important role of landscape heterogeneity in landscape ecology were reviewed. The inner and outer uncertain factors result in landscape heterogeneity. Landscape heterogeneity has close relations with landscape stability, landscape design, architecture, management and disturbance, scale and ecological diversity in ecology. Complexity of landscape heterogeneity research, non-system of measurement indices and methods, difficulties and limitations of landscape heterogeneity modelling were all discussed respectively. In addition, it is suggested that the theory and methods of ecological complexity should be used to improve landscape heterogeneity research.

  12. 40 CFR 159.167 - Discontinued studies. (United States)


    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Discontinued studies. 159.167 Section 159.167 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS STATEMENTS OF POLICIES AND INTERPRETATIONS Reporting Requirements for Risk/Benefit Information § 159.167 Discontinued studies. The fact that a study has...

  13. Discontinuities during UV writing of waveguides

    DEFF Research Database (Denmark)

    Svalgaard, Mikael; Harpøth, Anders; Andersen, Marc


    UV writing of waveguides can be hampered by discontinuities where the index change process suddenly shuts down. We show that thermal effects may account for this behaviour.......UV writing of waveguides can be hampered by discontinuities where the index change process suddenly shuts down. We show that thermal effects may account for this behaviour....

  14. A note on weakly discontinuous dynamical transitions. (United States)

    Franz, Silvio; Parisi, Giorgio; Ricci-Tersenghi, Federico; Rizzo, Tommaso; Urbani, Pierfrancesco


    We analyze mode coupling discontinuous transition in the limit of vanishing discontinuity, approaching the so called "A(3)" point. In these conditions structural relaxation and fluctuations appear to have universal form independent from the details of the system. The analysis of this limiting case suggests new ways for looking at the mode coupling equations in the general case.

  15. Changing Landscape

    DEFF Research Database (Denmark)

    Tunby Gulbrandsen, Ib; Kamstrup, Andreas; Koed Madsen, Anders

    to production, cooperation and communication. Following, we have witnessed a growing number of calls for attention to the effects of new ICT’s on the concept of strategic management and strategizing. Despite the numerous calls, few have answered. In this article we aim at providing a possible response beginning...... with an analysis of the changing organizational landscape created by new ICT’s like Google, Facebook, Wikipedia, iPods, smart phones and Wi-Fi. Based on five netno- and ethno-graphic investigations of the intertwinement of ICT’s and organizational work, we point to three features that have changed the scene: new...

  16. Cuban Landscapes

    DEFF Research Database (Denmark)

    Scarpaci, Joseph L.; Portela, Armando

    This accessible book offers a vivid geographic portrait of Cuba, exploring the island’s streetscapes, sugar cane fields, beaches, and rural settlements; its billboards, government buildings, and national landmarks. The authors illuminate how natural and built landscapes have shaped Cuban identity...... (cubanidad), and vice versa. They provide a unique perspective on Cuba’s distinct historical periods and political economies, from the colonial period through republicanism and today’s socialist era. Compelling topics include the legacies of slavery and the sugar industry, the past and future of urban...

  17. Vertebral Fractures After Discontinuation of Denosumab

    DEFF Research Database (Denmark)

    Cummings, Steven R; Ferrari, Serge; Eastell, Richard


    Denosumab reduces bone resorption and vertebral and nonvertebral fracture risk. Denosumab discontinuation increases bone turnover markers 3 months after a scheduled dose is omitted, reaching above-baseline levels by 6 months, and decreases bone mineral density (BMD) to baseline levels by 12 months....... We analyzed the risk of new or worsening vertebral fractures, especially multiple vertebral fractures, in participants who discontinued denosumab during the FREEDOM study or its Extension. Participants received ≥2 doses of denosumab or placebo Q6M, discontinued treatment, and stayed in the study ≥7...... months after the last dose. Of 1001 participants who discontinued denosumab during FREEDOM or Extension, the vertebral fracture rate increased from 1.2 per 100 participant-years during the on-treatment period to 7.1, similar to participants who received and then discontinued placebo (n = 470; 8.5 per 100...

  18. Historical transformation and epistemological discontinuity

    Directory of Open Access Journals (Sweden)

    Močnik Rastko


    Full Text Available Starting from recent formulas of EU bureaucracy for subordinating scientific and educational apparatuses to the needs of the capital and to the requests of its political representatives, the article analyses the interconnection between the historical transformation of the ideological state apparatuses (universities, higher education institutions, research institutes etc. and the epistemological discontinuity provoked by the triumph of technosciences. The hypothesis to be tested is the following: While the crisis of West European-North American capitalism requires an ever tighter submission of ideological state apparatuses, and especially of scientific and academic apparatuses to the needs of the capital, theoretical practices in the humanities and social sciences have come to the point where they entered into an open conflict with the domination of the capital and have, as a consequence, started to subvert their own institutional supports in the ideological apparatuses of the capitalist state. For this purpose, the article reconsiders social sciences as a compromise formation and, eventually, reassesses the historical materialism as a non-Cartesian modern science.

  19. PESP Landscaping Initiative (United States)

    Landscaping practices can positively or negatively affect local environments and human health. The Landscaping Initiative seeks to enhance benefits of landscaping while reducing need for pesticides, fertilizers, etc., by working with partners.

  20. Numerical Dissipation and Subgrid Scale Modeling for Separated Flows at Moderate Reynolds Numbers (United States)

    Cadieux, Francois; Domaradzki, Julian Andrzej


    Flows in rotating machinery, for unmanned and micro aerial vehicles, wind turbines, and propellers consist of different flow regimes. First, a laminar boundary layer is followed by a laminar separation bubble with a shear layer on top of it that experiences transition to turbulence. The separated turbulent flow then reattaches and evolves downstream from a nonequilibrium turbulent boundary layer to an equilibrium one. In previous work, the capability of LES to reduce the resolution requirements down to 1 % of DNS resolution for such flows was demonstrated (Cadieux et al., JFE 136-6). However, under-resolved DNS agreed better with the benchmark DNS than simulations with explicit SGS modeling because numerical dissipation and filtering alone acted as a surrogate SGS dissipation. In the present work numerical viscosity is quantified using a new method proposed recently by Schranner et al. and its effects are analyzed and compared to turbulent eddy viscosities of explicit SGS models. The effect of different SGS models on a simulation of the same flow using a non-dissipative code is also explored. Supported by NSF.

  1. Accounting for subgrid scale topographic variations in flood propagation modeling using MODFLOW

    DEFF Research Database (Denmark)

    Milzow, Christian; Kinzelbach, W.


    To be computationally viable, grid-based spatially distributed hydrological models of large wetlands or floodplains must be set up using relatively large cells (order of hundreds of meters to kilometers). Computational costs are especially high when considering the numerous model runs or model time...

  2. A Dynamic Subgrid Scale Model for Large Eddy Simulations Based on the Mori-Zwanzig Formalism

    CERN Document Server

    Parish, Eric J


    The development of reduced models for complex systems that lack scale separation remains one of the principal challenges in computational physics. The optimal prediction framework of Chorin et al., which is a reformulation of the Mori-Zwanzig (M-Z) formalism of non-equilibrium statistical mechanics, provides a methodology for the development of mathematically-derived reduced models of dynamical systems. Several promising models have emerged from the optimal prediction community and have found application in molecular dynamics and turbulent flows. In this work, a novel M-Z-based closure model that addresses some of the deficiencies of existing methods is developed. The model is constructed by exploiting similarities between two levels of coarse-graining via the Germano identity of fluid mechanics and by assuming that memory effects have a finite temporal support. The appeal of the proposed model, which will be referred to as the `dynamic-$\\tau$' model, is that it is parameter-free and has a structural form imp...

  3. On the Effect of an Anisotropy-Resolving Subgrid-Scale Model on Turbulent Vortex Motions (United States)


    expression coincides with the modified Leonard stress proposed by Ger- mano et al. (1991). In this model, the SGS turbulence energy kSGS may be evaluated as... mano subgridscale closure method. Phys. Fluids A, Vol. 4, pp. 633-635. Morinishi, Y. and Vasilyev, O.V. (2001), A recommended modification to the

  4. Parameterization for subgrid-scale motion of ice-shelf calving fronts

    Directory of Open Access Journals (Sweden)

    T. Albrecht


    Full Text Available A parameterization for the motion of ice-shelf fronts on a Cartesian grid in finite-difference land-ice models is presented. The scheme prevents artificial thinning of the ice shelf at its edge, which occurs due to the finite resolution of the model. The intuitive numerical implementation diminishes numerical dispersion at the ice front and enables the application of physical boundary conditions to improve the calculation of stress and velocity fields throughout the ice-sheet-shelf system. Numerical properties of this subgrid modification are assessed in the Potsdam Parallel Ice Sheet Model (PISM-PIK for different geometries in one and two horizontal dimensions and are verified against an analytical solution in a flow-line setup.

  5. Final Report: Systematic Development of a Subgrid Scaling Framework to Improve Land Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Dickinson, Robert Earl [Univ. of Texas, Austin, TX (United States)


    We carried out research to development improvements of the land component of climate models and to understand the role of land in climate variability and change. A highlight was the development of a 3D canopy radiation model. More than a dozen publications resulted.

  6. Discontinuance of ADHD Treatment in Adolescents

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap


    Full Text Available Prevalence of ADHD drug discontinuance in adolescents and young adults was studied in the UK by using the General Practice Database for patients aged 15-21 years from 1999 to 2006.

  7. Neural networks with discontinuous/impact activations

    CERN Document Server

    Akhmet, Marat


    This book presents as its main subject new models in mathematical neuroscience. A wide range of neural networks models with discontinuities are discussed, including impulsive differential equations, differential equations with piecewise constant arguments, and models of mixed type. These models involve discontinuities, which are natural because huge velocities and short distances are usually observed in devices modeling the networks. A discussion of the models, appropriate for the proposed applications, is also provided. This book also: Explores questions related to the biological underpinning for models of neural networks\\ Considers neural networks modeling using differential equations with impulsive and piecewise constant argument discontinuities Provides all necessary mathematical basics for application to the theory of neural networks Neural Networks with Discontinuous/Impact Activations is an ideal book for researchers and professionals in the field of engineering mathematics that have an interest in app...

  8. Ezogabine skin discoloration is reversible after discontinuation

    Directory of Open Access Journals (Sweden)

    Sally V. Mathias


    Full Text Available There is concern that bluish skin discoloration associated with ezogabine treatment could be permanent. We present a case of ezogabine-induced skin discoloration that resolved completely after discontinuation. A 55-year-old woman started ezogabine 400 mg three times a day at age 41. Bluish pigmentation over the toe nails, finger nails, around eyes and over and around lips was first noted after 5 years of treatment. Ezogabine was discontinued eight years after initiation. Skin discoloration improved within 6 months and completely resolved within 6 years of discontinuation. This case suggests that ezogabine-induced discoloration is reversible after discontinuation of treatment.

  9. Discontinuous Galerkin for the Radiative Transport Equation

    KAUST Repository

    Guermond, Jean-Luc


    This note presents some recent results regarding the approximation of the linear radiative transfer equation using discontinuous Galerkin methods. The locking effect occurring in the diffusion limit with the upwind numerical flux is investigated and a correction technique is proposed.

  10. Management applications of discontinuity theory | Science ... (United States)

    1.Human impacts on the environment are multifaceted and can occur across distinct spatiotemporal scales. Ecological responses to environmental change are therefore difficult to predict, and entail large degrees of uncertainty. Such uncertainty requires robust tools for management to sustain ecosystem goods and services and maintain resilient ecosystems. 2.We propose an approach based on discontinuity theory that accounts for patterns and processes at distinct spatial and temporal scales, an inherent property of ecological systems. Discontinuity theory has not been applied in natural resource management and could therefore improve ecosystem management because it explicitly accounts for ecological complexity. 3.Synthesis and applications. We highlight the application of discontinuity approaches for meeting management goals. Specifically, discontinuity approaches have significant potential to measure and thus understand the resilience of ecosystems, to objectively identify critical scales of space and time in ecological systems at which human impact might be most severe, to provide warning indicators of regime change, to help predict and understand biological invasions and extinctions and to focus monitoring efforts. Discontinuity theory can complement current approaches, providing a broader paradigm for ecological management and conservation This manuscript provides insight on using discontinuity approaches to aid in managing complex ecological systems. In part

  11. Landscaping for energy efficiency

    Energy Technology Data Exchange (ETDEWEB)



    This publication by the National Renewable Energy Laboratory addresses the use of landscaping for energy efficiency. The topics of the publication include minimizing energy expenses; landscaping for a cleaner environment; climate, site, and design considerations; planning landscape; and selecting and planting trees and shrubs. A source list for more information on landscaping for energy efficiency and a reading list are included.

  12. Exploring the Visual Landscape

    NARCIS (Netherlands)

    Nijhuis, S.; Van Lammeren, R.; Van der Hoeven, F.


    Exploring the Visual Landscape is about the combination of landscape research and planning, visual perception and Geographic Information Science. It showcases possible ways of getting a grip on themes like: landscape openness, cluttering of the rural landscape, high-rise buildings in relation to

  13. Discontinuation Decision in Assisted Reproductive Techniques

    Directory of Open Access Journals (Sweden)

    Ashraf Moini


    Full Text Available Background: In vitro fertilization (IVF and intra cytoplasmic sperm injection (ICSI are recognizedas established and increasingly successful forms of treatment for infertility, yet significant numbersof couples discontinue treatment without achieving a live birth. This study aims to identify majorfactors that influence the decision to discontinue IVF/ICSI treatments.Materials and Methods: We studied the data of 338 couples who discontinued their infertilitytreatments after three cycles; based on medical records and phone contact. The main measure wasthe reason for stopping their treatments.Results: Economical problems were cited by 212 couples (62.7%, as their mean income wassignificantly less than other couples (p<0.0001. Lack of success was reported as a reason by229 (67.8%, from whom 165 (72% also had economical problems. Achieving independent-ART pregnancy was the reason for discontinuation in 20 (5.9% couples. Psychological stress,depression and anxiety were reported as other cessation factors by 169 (50%, 148 (43.8% and 182(53.8% couples, respectively.Conclusion: This survey suggests that the most common reasons for assisted reproductivetechnique (ART discontinuation after three cycles are: prior unsuccessful cycles, economicaland psychological problems. Therefore, the substantial proportion of couples could benefit frompsychological intervention, increasing awareness of ART outcomes and health funding to copemore adequately with failed treatments.

  14. Effect of benzodiazepine discontinuation on dementia risk. (United States)

    Wu, Chi-Shin; Ting, Te-Tien; Wang, Sheng-Chang; Chang, I-Shou; Lin, Keh-Ming


    This study aimed to examine whether benzodiazepine (BZD) discontinuation would decrease the risk of dementia. A population-based nested case-control study of dementia was used. All subjects aged 45 years or older and enrolled in the National Health Insurance Research Database in Taiwan between 1997 and 2007 were randomly selected. A total of 8,434 cases had been identified with dementia at least three times in ambulatory claims or with one record in inpatient claims. They were individually matched with two comparison subjects (N = 16,706) by age, gender, and index date. The lengths of discontinuation, cumulative BZD dose, and potential confounding factors, including medical and psychiatric disorders, were measured and used for further analysis. Compared with nonusers, current users had an increased risk of dementia (adjusted odds ratio [aOR] = 2.71; 95% confidence interval [CI], 2.46-2.99). The dementia risk for former users was reduced as the duration of discontinuation lengthened (3 years aOR = 1.08, 95% CI, 0.98-1.20). The decreasing trend was significant (p discontinuation lengthened. Further investigations are needed to replicate this association and explore the underlying mechanism that links long-term BZD use, BZD discontinuation, and the pathogenesis of neurocognitive dysfunction.

  15. Discontinuous Galerkin Method for Hyperbolic Conservation Laws

    KAUST Repository

    Mousikou, Ioanna


    Hyperbolic conservation laws form a special class of partial differential equations. They describe phenomena that involve conserved quantities and their solutions show discontinuities which reflect the formation of shock waves. We consider one-dimensional systems of hyperbolic conservation laws and produce approximations using finite difference, finite volume and finite element methods. Due to stability issues of classical finite element methods for hyperbolic conservation laws, we study the discontinuous Galerkin method, which was recently introduced. The method involves completely discontinuous basis functions across each element and it can be considered as a combination of finite volume and finite element methods. We illustrate the implementation of discontinuous Galerkin method using Legendre polynomials, in case of scalar equations and in case of quasi-linear systems, and we review important theoretical results about stability and convergence of the method. The applications of finite volume and discontinuous Galerkin methods to linear and non-linear scalar equations, as well as to the system of elastodynamics, are exhibited.

  16. Social inequalities in early antidepressant discontinuation. (United States)

    Bocquier, Aurélie; Cortaredona, Sébastien; Verdoux, Hélène; Casanova, Ludovic; Sciortino, Vincent; Nauleau, Stève; Verger, Pierre


    This study aimed to test for social disparities in early discontinuation of antidepressant treatment and to explore associations with type of drug and composition of prescriber's clientele. The cohort was 14,518 Marseille residents (ages 18-64 years) covered by the National Health Insurance Fund who had a new episode of antidepressant treatment (specifically, no prescription claim in the six months before the index claim) prescribed by a private general practitioner in 2008 or 2009. Factors associated with early discontinuation (prescription filled or refilled fewer than four times in the six months after the index claim) were analyzed with multilevel models that were adjusted for patient morbidity and number of consultations with private general practitioners and psychiatrists. Sensitivity analyses were conducted with different definitions of new treatment and early discontinuation. Low income, type of antidepressant (tricyclics versus selective serotonin reuptake inhibitors), and prescribers' clientele composition (specifically, a high proportion of socioeconomically disadvantaged patients) were independently associated with an increased risk of early antidepressant discontinuation. A significant interaction was found between low income and gender. Low-income patients were more likely than other patients to receive tricyclic antidepressants. These results add further evidence of inequalities in care for major depression and suggest that women are at greater disadvantage than men. Educational programs for general practitioners should focus on the risks of antidepressant discontinuation among disadvantaged patients. Enhancing therapeutic education of low-income patients may improve their treatment adherence.

  17. 27 CFR 478.57 - Discontinuance of business. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Discontinuance of business... Licenses § 478.57 Discontinuance of business. (a) Where a firearm or ammunition business is either discontinued or succeeded by a new owner, the owner of the business discontinued or succeeded shall within 30...

  18. 27 CFR 555.128 - Discontinuance of business. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Discontinuance of business... Discontinuance of business. Where an explosive materials business or operations is discontinued and succeeded by... such facts and shall be delivered to the successor. Where discontinuance of the business or operations...

  19. Biodiversity and landscape (United States)

    Bridgewater, P. B.


    Biodiversity and landscape pattern and process are inextricably linked. Maximum biodiversity occurs where landscape patterns and processes are most heterogeneous. Human use of landscapes in Australia and New Zealand has changed biodiversity patterns. European settlement introduced many species from Europe, America, Africa and Asia to the landscapes of Australia and New Zealand. These species have caused a decline in native biodiversity of much greater significance than their addition to the biodiversity. Future landscape management should seek to maintain maximum landscape heterogeneity, thereby ensuring the maximum persistence of biodiversity.

  20. Identification of discontinuities in plasma plume evolution

    CERN Document Server

    Gojani, Ardian B; Obayashi, Shigeru


    The ejection of material during laser ablation gives rise to the development of discontinuities in the ambient gas. Several of these discontinuities are observed and characterized, including externally and internally propagating shock waves, contact surface, and the ionization front. Qualitative experimental observations and analysis of these discontinuities is presented. Results from shadowgraphy enabled determination of an irradiance threshold between two different ablation mechanisms, and determination of several stages of plasma plume evolution. Consideration of the refractive index as a dynamic sum of the contributions from gas and electrons led to separate identification of ionization front from the contact surface. Furthermore, ionization front was observed to lead the shock wave at the earlier stage of the ablation.

  1. Pharmacologic strategies for discontinuing benzodiazepine treatment. (United States)

    Rickels, K; DeMartinis, N; Rynn, M; Mandos, L


    Benzodiazepines have been shown to have broad-spectrum activity, rapid onset of action, and a wide therapeutic window compared with other anxiolytic medications. Yet the use of benzodiazepines has been limited by concern regarding dependence, withdrawal, and abuse. Agents such as antidepressants, serotonergic anxiolytics, anticonvulsants, and beta-blockers have been used with varying degrees of success to help facilitate the tapering of benzodiazepines. Carbamazepine, imipramine, valproate, and trazodone have been beneficial in the management of benzodiazepine discontinuation, but not in decreasing the severity of benzodiazepine withdrawal. A stepwise approach to discontinuing benzodiazepines is offered.

  2. Measures of discontinuities for crystal damaging (United States)

    Zubko, I. Yu.


    Single crystal equilibrium states with discontinuities have been obtained under uniaxial stretching using discrete atomistic simulation. These states may contain different numbers of defects depending on the applied mechanical energy. The increase of the applied energy via specimen elongation leads to bifurcations of the internal material degree of freedom. Each bifurcation is accompanied with a jump of the internal energy and formation of a new discontinuity. Several parameters were considered as the applicants to be a measure of the defect structure (internal degree of freedom). The averaged gradient of the local material density logarithm was chosen as one of the most appropriate variants.

  3. Computers and the landscape (United States)

    Gary H. Elsner


    Computers can analyze and help to plan the visual aspects of large wildland landscapes. This paper categorizes and explains current computer methods available. It also contains a futuristic dialogue between a landscape architect and a computer.

  4. Characterizing European cultural landscapes

    DEFF Research Database (Denmark)

    Tieskens, Koen F.; Schulp, Catharina J E; Levers, Christian


    Almost all rural areas in Europe have been shaped or altered by humans and can be considered cultural landscapes, many of which now are considered to entail valuable cultural heritage. Current dynamics in land management have put cultural landscapes under a huge pressure of agricultural...... intensification and land abandonment. To prevent the loss of cultural landscapes, knowledge on the location of different types of cultural landscapes is needed. In this paper, we present a characterization of European cultural landscapes based on the prevalence of three key dimensions of cultural landscapes......: landscape structure, management intensity, and value and meaning. We mapped these dimensions across Europe at a 1-km resolution by combining proxies on management intensity and landscape structure with new indicators such as social media usage and registered traditional food products. We integrated...

  5. Orthokeratology vs. spectacles: adverse events and discontinuations. (United States)

    Santodomingo-Rubido, Jacinto; Villa-Collar, César; Gilmartin, Bernard; Gutiérrez-Ortega, Ramón


    To assess the relative clinical success of orthokeratology contact lenses (OK) and distance single-vision spectacles (SV) in children in terms of incidences of adverse events and discontinuations over a 2-year period. Sixty-one subjects 6 to 12 years of age with myopia of - 0.75 to - 4.00DS and astigmatism ≤1.00DC were prospectively allocated OK or SV correction. Subjects were followed at 6-month intervals and advised to report to the clinic immediately should adverse events occur. Adverse events were categorized into serious, significant, and non-significant. Discontinuation was defined as cessation of lens wear for the remainder of the study. Thirty-one children were corrected with OK and 30 with SV. A higher incidence of adverse events was found with OK compared with SV (p < 0.001). Nine OK subjects experienced 16 adverse events (7 significant and 9 non-significant). No adverse events were found in the SV group. Most adverse events were found between 6 and 12 months of lens wear, with 11 solely attributable to OK wear. Significantly more discontinuations were found with SV in comparison with OK (p < 0.05). The relatively low incidence of adverse events and discontinuations with OK is conducive for the correction of myopia in children with OK contact lenses.

  6. Discontinuous precipitation in copper base alloys

    Indian Academy of Sciences (India)


    Abstract. Discontinuous precipitation (DP) is associated with grain boundary migration in the wake of which alternate plates of the precipitate and the depleted matrix form. Some copper base alloys show DP while others do not. In this paper the misfit strain parameter, η, has been calculated and predicted that if.

  7. Forecasting Technological Discontinuities in the ICT Industry

    DEFF Research Database (Denmark)

    Hoisl, Karin; Stelzer, Tobias; Biala, Stefanie


    in the ICT industry. The conjoint approach allows for a simulation of the forecasting process and considers utility trade-offs. The results show that for both types of experts the perceived benefit of users most highly contributes to predicting technological discontinuities. Internal experts assign more...

  8. 38 CFR 21.4135 - Discontinuance dates. (United States)


    ...(g), 3532(e)) (n) Fugitive felons: veterans eligible under 38 U.S.C. chapter 32. VA will not award..., during which the veteran is a fugitive felon. The date of discontinuance of an award of educational assistance allowance to a veteran who is a fugitive felon is the later of— (1) The date of the warrant for...

  9. 38 CFR 21.7135 - Discontinuance dates. (United States)


    ..., 3676, 3680A(a)) (aa) Fugitive felons. (1) VA will not award educational assistance allowance to an... felon. The date of discontinuance of an award of educational assistance allowance to a veteran who is a fugitive felon is the later of— (i) The date of the warrant for the arrest of the felon; or (ii) December...

  10. Discontinuous Galerkin finite element discretization for steady ...

    African Journals Online (AJOL)

    ... means of a generalization of the Babuska-Brezzi theory for mixed problems. Finally, a priori error estimates using energy norm for both the velocity and pressure are obtained. Keywords: Stokes equations, slip boundary condition, variational inequality, discontinuous Galerkin method, a priori error estimate, convergence


    African Journals Online (AJOL)


    Jun 30, 2014 ... In the vicinity of the interface, we observe a kind of discontinuity in the evolution of the electric field intensity. This one becomes greater than the value obtained in the case of gaps with homogeneous plane earth. Key words: breakdown voltage; electric field; distributed capacity. Author Correspondence ...

  12. 38 CFR 21.7635 - Discontinuance dates. (United States)


    ...) VOCATIONAL REHABILITATION AND EDUCATION Educational Assistance for Members of the Selected Reserve Payments...) In all other cases if the reservist dies while pursuing a program of education, the discontinuance... practices of the institution of higher learning. (Authority: 10 U.S.C. 16136(b), 38 U.S.C. 3680(a); Pub. L...

  13. Factors Influencing Contraceptive Choice and Discontinuation ...

    African Journals Online (AJOL)

    Some women indicated that their HIV status dictated contraceptive decisions, particularly with regard to abstinence. Women reported method discontinuation because of side effects, having met desired parity, and menstrual changes. Findings suggested that perceptions about side effects, opinions of the male partner, and ...

  14. Effect of grain boundary misorientation on discontinuous ...

    Indian Academy of Sciences (India)


    showed that the discontinuous precipitation (DP) reaction rate was dependent on the geometry of the grain boundary in ... 80% thickness reduction) had no effect on the frequency of special-grain boundaries. Keywords. AZ91 alloy .... increasing solute concentration, the influence of the ener- getics and kinetics is diminished ...

  15. Discontinuous precipitation in copper base alloys

    Indian Academy of Sciences (India)

    Discontinuous precipitation (DP) is associated with grain boundary migration in the wake of which alternate plates of the precipitate and the depleted matrix form. Some copper base alloys show DP while others do not. In this paper the misfit strain parameter, , has been calculated and predicted that if 100 > ± 0.1, DP is ...

  16. Problems with Discontinuous Diffusion/Dispersion Coefficients

    Directory of Open Access Journals (Sweden)

    Stefano Ferraris


    accurate on smooth solutions and based on a special numerical treatment of the diffusion/dispersion coefficients that makes its application possible also when such coefficients are discontinuous. Numerical experiments confirm the convergence of the numerical approximation and show a good behavior on a set of benchmark problems in two space dimensions.

  17. Reasons for (not) discontinuing antipsychotics in dementia

    NARCIS (Netherlands)

    Janus, Sarah; van Manen, Jeanette Gabrielle; Zuidema, Sytse U.; Snijder, Carina; Drossaert, Constance H.C.; IJzerman, Maarten Joost


    Background The gap between high antipsychotic prescription rates for patients with dementia and the guidelines’ advice to prescribe cautiously indicates that barriers to discontinuation exist. This exploratory study used the theory of planned behaviour to give a first overview of the factors that

  18. An equilibrium closure result for discontinuous games

    NARCIS (Netherlands)

    Balder, E.J.


    For games with discontinuous payoffs Simon and Zame (1990) introduced payoff indeterminacy, in the form of endogenous sharing rules, which are measurable selections of a certain payoff correspondence. Their main result concerns the existence of a mixed Nash equilibrium and an associated sharing

  19. Contraceptive Discontinuation and Switching Among Ghanaian ...

    African Journals Online (AJOL)

    This study identifies factors associated with contraceptive discontinuation and switching among Ghanaian women of reproductive age, using data from 1,378 female respondents of the 2008 Ghana Demographic and Health Survey. Logistic regression models were used to determine relationships between key ...

  20. Flowscapes : Infrastructure as landscape, landscape as infrastructure. Graduation Lab Landscape Architecture 2012/2013

    NARCIS (Netherlands)

    Nijhuis, S.; Jauslin, D.; De Vries, C.


    Flowscapes explores infrastructure as a type of landscape and landscape as a type of infrastructure, and is focused on landscape architectonic design of transportation-, green- and water infrastructures. These landscape infrastructures are considered armatures for urban and rural development. With

  1. Thresholds for soil cover and weathering in mountainous landscapes (United States)

    Dixon, Jean; Benjaram, Sarah


    The patterns of soil formation, weathering, and erosion shape terrestrial landscapes, forming the foundation on which ecosystems and human civilizations are built. Several fundamental questions remain regarding how soils evolve, especially in mountainous landscapes where tectonics and climate exert complex forcings on erosion and weathering. In these systems, quantifying weathering is made difficult by the fact that soil cover is discontinuous and heterogeneous. Therefore, studies that attempt to measure soil weathering in such systems face a difficult bias in measurements towards more weathered portions of the landscape. Here, we explore current understanding of erosion-weathering feedbacks, and present new data from mountain systems in Western Montana. Using field mapping, analysis of LiDAR and remotely sensed land-cover data, and soil chemical analyses, we measure soil cover and surface weathering intensity across multiple spatial scales, from the individual soil profile to a landscape perspective. Our data suggest that local emergence of bedrock cover at the surface marks a landscape transition from supply to kinetic weathering regimes in these systems, and highlights the importance of characterizing complex critical zone architecture in mountain landscapes. This work provides new insight into how landscape morphology and erosion may drive important thresholds for soil cover and weathering.

  2. Creep Strength of Discontinuous Fibre Composites

    DEFF Research Database (Denmark)

    Pedersen, Ole Bøcker


    A unidirectional, discontinuous fibre composite is considered under conditions of steady state creep in the direction of reinforcement. The composite consists of noncreeping, discontinuous, perfectly aligned, uniformly distributed fibres which are perfectly bonded to a matrix obeying a power...... relation between stress and strain rate. Expressions for the interface stress, the creep velocity profile adjacent to the fibres and the creep strength of the composite are derived. Previous results for the creep strength, sc = aVfs0 ( \\frac[( Î )\\dot] [( Î )\\dot] 0 )1/nr1 + 1/n c=Vf001n1+1n in which[( Î...... )\\dot] is the composite creep rate,V f is the fibre volume fraction,sgr 0,epsi 0 andn are the constants in the matrix creep law. The creep strength coefficient agr is found to be very weakly dependent onV f and practically independent ofn whenn is greater than about 6....

  3. Mantle heterogeneity and the D" discontinuity (United States)

    Grocholski, B.; Catalli, K.; Shim, S.


    The observation of the D'' discontinuity, especially in regions of high shear-wave velocity, has been attributed to the thermal response of the perovskite (Pv) to post-perovskite (PPv) transition. This interpretation requires a large and positive Clapeyron slope in addition to a narrow two-phase region to be seismically detectable. Mineral physics experiments of this system have been evolving to investigate both chemical and mineralogical variations possible for the D'' region of the mantle. This has come with some surprises, including two-phase regions that would span hundreds of km depth in aluminum (Tateno et al., 2005), iron (Catalli et al., 2009), and mantle-relevant aluminum-iron bearing systems (Catalli et al., 2009, Andrault et al., 2010). Our most recent experimental results suggest that other minerals play an important role in partitioning iron and aluminum to decrease the thickness of the mixed phase region such that the transition will be seismically detectable. In particular, aluminum stabilizing Pv makes it challenging for the PPv transition to be detectable in a homogeneous (pyrolitic) mantle. However, subduction of oceanic lithosphere injects heterogeneous rock types (basaltic, harzburgitic) that are more likely to have seismically detectable transitions. Therefore, the mantle heterogeneities originated from recycled oceanic lithosphere may be responsible for the D'' discontinuity. Enriched, basalt-like compositions would be expected to have a discontinuity ˜400 km above the core-mantle boundary (CMB) possibly controlled by the appearance of a PbO2-like structured silica capable of dissolving large amounts of aluminum. Depleted, harzburgite-like mantle compositions are likely to have a transition ˜100 km above the CMB, which is sharp due to iron partitioning into ferropericlase combined with a low aluminum content. This picture of heterogeneity in the lowermost mantle not only helps explains the seismic results on the D'' discontinuity itself, but

  4. Recent landscape research in Hungary


    Csorba, Péter; Lóczy, Dénes; Mezosi, Gábor


    Both the study of landscape types and investigations of the interactions between landscape factors have a long tradition in Hungarian landscape geography. Major achievements in landscape synthesis were the two-volume Inventory of microregions in Hungary. In the various schools of landscape geography fundamental research is directed at investigations of landscape pattern, landscape sensitivity, geo-ecological mapping and urban ecology. The major trends in applied research are the optimisation ...

  5. Field Discontinuities and the Memory Effect (United States)

    Tolish, Alexander; Wald, Robert


    The ``memory effect,'' a permanent change in the separation of test particles after the passage of a pulse of gravitational radiation, is a well-defined and fairly well-understood phenomenon in spacetimes with a notion of null infinity. However, many valid questions remain unanswered. For example, how do we define memory in the absence of null infinity? Or, does memory depend on the precise details of the radiation source or just on the source's asymptotic behavior? We believe that such questions are best answered using a simplified, distributional model of memory. If we consider linearized gravity on fixed background spacetimes, we can study the scattering of point particles, which radiate metric perturbations with sharp, step-function wave fronts. These steps correspond to derivative-of-delta-function discontinuities in the curvature, and according to the geodesic deviation equation, it is these discontinuities (and these alone) that contribute to permanent, finite changes in test particle separation-i.e., memory. Using this analysis of field discontinuities (as well as scalar and electromagnetic analogues of gravitational memory) we can isolate the physics of the memory effect from other, background phenomena.

  6. 27 CFR 478.127 - Discontinuance of business. (United States)


    ... business was located: Provided, however, Where State law or local ordinance requires the delivery of... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Discontinuance of business... Records § 478.127 Discontinuance of business. Where a licensed business is discontinued and succeeded by a...

  7. 14 CFR 221.300 - Discontinuation of electronic tariff system. (United States)


    ... of electronic tariff system. In the event that the electronic tariff system is discontinued, or the source of the data is changed, or a filer discontinues its business, all electronic data records prior to... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Discontinuation of electronic tariff system...

  8. 25 CFR 175.21 - Discontinuance of service. (United States)


    ... Utility Service Administration § 175.21 Discontinuance of service. Failure of customer(s) to comply with... 25 Indians 1 2010-04-01 2010-04-01 false Discontinuance of service. 175.21 Section 175.21 Indians... service. The procedure(s) for discontinuance of service shall be set forth in the operations manual. ...

  9. Seismic wave propagation in fractured media: A discontinuous Galerkin approach

    KAUST Repository

    De Basabe, Jonás D.


    We formulate and implement a discontinuous Galekin method for elastic wave propagation that allows for discontinuities in the displacement field to simulate fractures or faults using the linear- slip model. We show numerical results using a 2D model with one linear- slip discontinuity and different frequencies. The results show a good agreement with analytic solutions. © 2011 Society of Exploration Geophysicists.

  10. Extreme interplanetary rotational discontinuities at 1 AU (United States)

    Lepping, R. P.; Wu, C.-C.


    This study is concerned with the identification and description of a special subset of four Wind interplanetary rotational discontinuities (from an earlier study of 134 directional discontinuities by Lepping et al. (2003)) with some "extreme" characteristics, in the sense that every case has (1) an almost planar current sheet surface, (2) a very large discontinuity angle (ω), (3) at least moderately strong normal field components (>0.8 nT), and (4) the overall set has a very broad range of transition layer thicknesses, with one being as thick as 50 RE and another at the other extreme being 1.6 RE, most being much thicker than are usually studied. Each example has a well-determined surface normal (n) according to minimum variance analysis and corroborated via time delay checking of the discontinuity with observations at IMP 8 by employing the local surface planarity. From the variance analyses, most of these cases had unusually large ratios of intermediate-to-minimum eigenvalues (λI/λmin), being on average 32 for three cases (with a fourth being much larger), indicating compact current sheet transition zones, another (the fifth) extreme property. For many years there has been a controversy as to the relative distribution of rotational (RDs) to tangential discontinuities (TDs) in the solar wind at 1 AU (and elsewhere, such as between the Sun and Earth), even to the point where some authors have suggested that RDs with large ∣Bn∣s are probably not generated or, if generated, are unstable and therefore very rare. Some of this disagreement apparently has been due to the different selection criteria used, e.g., some allowed eigenvalue ratios (λI/λmin) to be almost an order of magnitude lower than 32 in estimating n, usually introducing unacceptable error in n and therefore also in ∣Bn∣. However, we suggest that RDs may not be so rare at 1 AU, but good quality cases (where ∣Bn∣ confidently exceeds the error in ∣Bn∣) appear to be uncommon, and further

  11. Why do patients discontinue fertility treatment? A systematic review of reasons and predictors of discontinuation in fertility treatment

    NARCIS (Netherlands)

    Gameiro, S.; Boivin, J.; Peronace, L.; Verhaak, C.M.


    BACKGROUND Chances of achieving parenthood are high for couples who undergo fertility treatment. However, many choose to discontinue before conceiving. A systematic review was conducted to investigate patients' stated reasons for and predictors of discontinuation at five fertility treatment stages.

  12. Lines of landscape organisation

    DEFF Research Database (Denmark)

    Løvschal, Mette


    This paper offers a landscape analysis of the earliest linear landscape boundaries on Skovbjerg Moraine, Denmark, during the first millennium BC. Using Delaunay triangulation as well as classic distribution analyses, it demonstrates that landscape boundaries articulated already established use......-patterns close to roads, but also intercepted the central lines of movement and conflicted with previous ways of organizing the landscape. This development is interpreted as a different form of large-scale landholding, in which livestock possibly played a dominant role and boundaries were used to confiscate land...... in the zones bordering suitable pastures. This situation shows obvious parallels with southern Britain centuries earlier. It is discussed how the study of these physical boundaries provides new insights into the organization of pre-Roman landscapes, not only demonstrating a continuing engagement with landscape...

  13. Genomic Energy Landscapes. (United States)

    Zhang, Bin; Wolynes, Peter G


    Energy landscape theory, developed in the context of protein folding, provides, to our knowledge, a new perspective on chromosome architecture. We review what has been learned concerning the topology and structure of both the interphase and mitotic chromosomes from effective energy landscapes constructed using Hi-C data. Energy landscape thinking raises new questions about the nonequilibrium dynamics of the chromosome and gene regulation. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  14. Dartmoor: A Landscape Study


    Klemen, P. K.


    At the heart of Devon in the southwest of England lies Dartmoor, a large expanse of high moorland and rocky tors. Anyone who has visited Dartmoor or seen photographs and read about it will have their own personal images and feelings for the place, which will be as varied as the landscape. Over recent years landscape approaches have adopted strategies to understand how people experience and perceive the landscape that surrounds them (Ingold 2000, Thomas 1999, Tilley 1994). Phenomenology attemp...

  15. Landscape Ecology and problems of European cultural landscapes

    DEFF Research Database (Denmark)

    Brandt, Jesper


    Parallel to a growing global cooperation among landscape ecologists, different regional trends within landscape ecology seems to arise, related to different geographical and historical conditions. Modern landscape ecology in Europe has developed as an interdisciplinary activity inspired by practi...

  16. Landscape agronomy : a new field for addressing agricultural landscape dynamics


    Marraccini, Élisa; Moonen, Anna Camilla; Galli, Mariassunta; Lardon, Sylvie; Rapey, Hélène; Thenail, Claudine; Bonari, Enrico


    Landscape dynamics increasingly challenge agronomists to explain how and why agricultural landscapes are designed and managed by farmers. Nevertheless, agronomy is rarely included in the wide range of disciplines involved in landscape research. In this paper, we describe how landscape agronomy can help explain the relationship between farming systems and agricultural landscape dynamics. For this, we propose a conceptual model of agricultural landscape dynamics that illustrates the specific co...

  17. Lorazepam discontinuation promotes 'inverse agonist' effects of benzodiazepines. (United States)

    Schatzki, A.; Lopez, F.; Greenblatt, D. J.; Shader, R. I.; Miller, L. G.


    1. The effects of lorazepam discontinuation on responses to benzodiazepine agonists and antagonists were studied in mice. 2. The convulsant dose of pentylenetetrazol was decreased after an acute dose of lorazepam (0.5 mg kg-1) at 4 days after drug discontinuation, compared to 1 or 7 days after discontinuation or to vehicle treatment. 3. The percentage of mice undergoing convulsions after an acute dose of FG 7142 (40 mg kg-1) was increased at 4 days after lorazepam discontinuation, compared to 1 or 7 days after discontinuation or to vehicle treatment. 4. After an acute dose (0.5 mg kg-1), lorazepam concentrations in cortex tended to be greater in lorazepam-treated compared to vehicle-treated mice at 4 days after discontinuation compared to 1 and 7 days. 5. These data indicate a shift toward reduced agonist sensitivity and increased inverse agonist sensitivity in mice 4 days after lorazepam discontinuation. PMID:2573401

  18. Discontinuous Deformation Analysis Coupling with Discontinuous Galerkin Finite Element Methods for Contact Simulations

    Directory of Open Access Journals (Sweden)

    Yue Sun


    Full Text Available A novel coupling scheme is presented to combine the discontinuous deformation analysis (DDA and the interior penalty Galerkin (IPG method for the modeling of contacts. The simultaneous equilibrium equations are assembled in a mixed strategy, where the entries are derived from both discontinuous Galerkin variational formulations and the strain energies of DDA contact springs. The contact algorithms of the DDA are generalized for element contacts, including contact detection criteria, open-close iteration, and contact submatrices. Three representative numerical examples on contact problems are conducted. Comparative investigations on the results obtained by our coupling scheme, ANSYS, and analytical theories demonstrate the accuracy and effectiveness of the proposed method.

  19. Energy Landscapes and the Landscape of Fear. (United States)

    Gallagher, Austin J; Creel, Scott; Wilson, Rory P; Cooke, Steven J


    Animals are not distributed randomly in space and time because their movement ecology is influenced by a variety of factors. Energy landscapes and the landscape of fear have recently emerged as largely independent paradigms, both reshaping our perspectives and thinking relating to the spatial ecology of animals across heterogeneous landscapes. We argue that these paradigms are not distinct but rather complementary, collectively providing a better mechanistic basis for understanding the spatial ecology and decision-making of wild animals. We discuss the theoretical underpinnings of each paradigm and illuminate their complementary nature through case studies, then integrate these concepts quantitatively by constructing quantitative pathways of movement modulated by energy and fear to elucidate the mechanisms underlying the spatial ecology of wild animals. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Discontinuation of the Bulletin's menu page

    CERN Multimedia

    Publications Section


    The menus of the various CERN restaurants will no longer be published in the Bulletin as of Monday 4 April (issue No. 14/2005). The menu pages are being discontinued both as a savings measure and due to the low level of interest in this section of the Bulletin. The most recent survey of Bulletin readers showed that only 13% of the people questioned regularly read the menu section, compared to between 40% and 85% in the case of the other sections. Publications Section SG/CO Tel. 79971

  1. Discontinuation of the Bulletin's menu page

    CERN Multimedia

    Publications Section


    The menus of the various CERN restaurants will no longer be published in the Bulletin as of Monday 4 April (issue No. 14/2005). The menu pages are being discontinued both as a savings measure and due to the low level of interest in this section of the Bulletin. The most recent survey of Bulletin readers showed that only 13% of the people questioned regularly read the menu section, compared to between 40% and 85% in the case of the other sections. Publications Section DSU-CO Tel. 79971

  2. Diffusion piecewise homogenization via flux discontinuity factors

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, Richard; Zmijarevic, Igor, E-mail:, E-mail: [Commissariat a l' Energie Atomique et aux Energies Alternatives, Service d' Etudes de Reacteurs et de Mathematiques Appliquees, Gif-sur-Yvette cedex (France)


    We analyze the calculation of flux discontinuity factors (FDFs) for use with piecewise subdomain assembly homogenization. These coefficients depend on the numerical mesh used to compute the diffusion problem. When the mesh has a single degree of freedom on subdomain interfaces the solution is unique and can be computed independently per subdomain. For all other cases we have implemented an iterative calculation for the FDFs. Our numerical results show that there is no solution to this nonlinear problem but that the iterative algorithm converges towards FDFs values that reproduce subdomains reaction rates with a relatively high precision. In our test we have included both the GET and black-box FDFs. (author)

  3. Singularity and dynamics on discontinuous vector fields

    CERN Document Server

    Luo, Albert CJ


    This book discussed fundamental problems in dynamics, which extensively exist in engineering, natural and social sciences. The book presented a basic theory for the interactions among many dynamical systems and for a system whose motions are constrained naturally or artificially. The methodology and techniques presented in this book are applicable to discontinuous dynamical systems in physics, engineering and control. In addition, they may provide useful tools to solve non-traditional dynamics in biology, stock market and internet network et al, which cannot be easily solved by the traditional

  4. Principles of landscape architecture

    NARCIS (Netherlands)

    Nijhuis, S.


    The Department of Urbanism at the Faculty of Architecture and Built Environment, TU Delft considers urbanism as a planning and design oriented activity towards urban and rural landscapes. It aims to enhance, restore or create landscapes from a perspective of sustainable development, so as to guide,

  5. The Value of Landscaping


    Relf, Diane


    Landscaping is one of the most cost effective tools for improving and sustaining the quality of life, whether in the city, the suburbs, or the country. Landscaping is an integral part of our culture and plays an essential role in the quality of our environment, affecting our economic well-being and our physical and psychological health.

  6. Glossary on agricultural landscapes.

    NARCIS (Netherlands)

    Kruse, A.; Centeri, C.; Renes, J.; Roth, M.; Printsman, A.; Palang, H.; Benito Jorda, M.-D.; Verlarde, M.D.; Kruckenberg, H.


    T he following glossary of terms related to the European agricultural landscape shall serve as a common basis for all parties, working in or on agricultural landscapes. Some of the terms are quite common and sometimes used in our every day language, but they often have different meanings in

  7. Retrospective landscape analysis

    DEFF Research Database (Denmark)

    Fritzbøger, Bo


    On the basis of maps from the 18th and 19th centuries, a retrospective analysis was carried out of documentary settlement and landscape data extending back to the Middle Ages with the intention of identifying and dating general structural and dynamic features of the cultural landscape in a selected...

  8. Urban Landscape Perspectives

    Directory of Open Access Journals (Sweden)

    Frederick Steiner


    Full Text Available Cities present significant opportunities for new landscape perspectives that can help inform conservation and development decisions. Early in the twenty-first century, the majority of the planet’s population became urban as more people lived in city-regions for the first time in our history. As the global population increases, so does this urbanization. The environmental challenges of population and urban growth are profound. Landscapes represent a synthesis of natural and cultural processes. Cities are certainly cultural phenomena. Historically, cities provided refuge from nature. The expanding field of urban ecology, coupled with landscape ecology, can enhance how the dual natural and cultural dimensions of landscapes in cities are understood. Furthermore, concepts such as ecosystem services and green infrastructure are proving useful for urban landscape planning and design. Examples from Dayton, Ohio; Brooklyn, New York; and Austin, Texas are presented.

  9. Medication Discontinuation in Patients After Discharge From a Psychiatric Hospital. (United States)

    Abdullah-Koolmees, Heshu; Gardarsdottir, Helga; Yazir, Dilek; Stoker, Lennart J; Vuyk, Judith; Egberts, Toine C G; Heerdink, Eibert R


    Patients discharged from psychiatric hospitals may be at risk for intentional or unintentional discontinuation of their medication. To describe and assess the discontinuation of, and changes to, psychiatric and/or somatic medication in patients after discharge from psychiatric hospitals. A retrospective follow-up study was conducted in patients discharged from 4 psychiatric hospitals in The Netherlands between 2006 and 2009. Patients' medication use during the last 2 days of hospitalization was compared with medication dispensed during the 3 months following discharge. Changes in psychiatric and somatic medication were investigated and defined as medication discontinuation, start, or switch. Patients were classified as continuing users, when there were no changes to the medication after discharge. Relative risks with 95% confidence intervals to measure differences in discontinuation were estimated using Cox regression analysis. This study included 1324 patients, 69.8% of whom discontinued medication, and 9.7% switched one or more medications. Nearly half (47.4%) of all patients started a medication other than that dispensed during the last 2 days of hospitalization, and 13.7% of all patients experienced no changes to their medication regimen. Approximately 40% of the patients discontinued one or more medications for chronic conditions. From these, 68% discontinued psychiatric medications and 49.4% discontinued somatic medications. A quarter (25.2%) of the 644 patients discontinued using antipsychotics. More than a quarter (28.4%) of the 292 patients using medications for cardiovascular problems discontinued. Patients using as-needed medication prior to discharge were more likely to discontinue their medication (relative risk = 1.85; 95% confidence interval = 1.55-2.20). Discharge from a psychiatric hospital led to medication discontinuation in approximately 70% of all patients. Approximately 40% of the patients discontinued medications for chronic conditions

  10. Rock discontinuity surface roughness variation with scale (United States)

    Bitenc, Maja; Kieffer, D. Scott; Khoshelham, Kourosh


    ABSTRACT: Rock discontinuity surface roughness refers to local departures of the discontinuity surface from planarity and is an important factor influencing the shear resistance. In practice, the Joint Roughness Coefficient (JRC) roughness parameter is commonly relied upon and input to a shear strength criterion such as developed by Barton and Choubey [1977]. The estimation of roughness by JRC is hindered firstly by the subjective nature of visually comparing the joint profile to the ten standard profiles. Secondly, when correlating the standard JRC values and other objective measures of roughness, the roughness idealization is limited to a 2D profile of 10 cm length. With the advance of measuring technologies that provide accurate and high resolution 3D data of surface topography on different scales, new 3D roughness parameters have been developed. A desirable parameter is one that describes rock surface geometry as well as the direction and scale dependency of roughness. In this research a 3D roughness parameter developed by Grasselli [2001] and adapted by Tatone and Grasselli [2009] is adopted. It characterizes surface topography as the cumulative distribution of local apparent inclination of asperities with respect to the shear strength (analysis) direction. Thus, the 3D roughness parameter describes the roughness amplitude and anisotropy (direction dependency), but does not capture the scale properties. In different studies the roughness scale-dependency has been attributed to data resolution or size of the surface joint (see a summary of researches in [Tatone and Grasselli, 2012]). Clearly, the lower resolution results in lower roughness. On the other hand, have the investigations of surface size effect produced conflicting results. While some studies have shown a decrease in roughness with increasing discontinuity size (negative scale effect), others have shown the existence of positive scale effects, or both positive and negative scale effects. We

  11. Investigation of Soil and Vegetation Characteristics in Discontinuous Permafrost Landscapes Near Fairbanks, Alaska (United States)


    nation’s public good. Find out more at To search for other technical reports published by ERDC, visit the ERDC online library at...Lichvar et al. 2014). The current report uses common names, but the appendices contain scien - tific names, references, and wetland plant indicator

  12. Quantitative identification of technological discontinuities using simulation modeling

    CERN Document Server

    Park, Hyunseok


    The aim of this paper is to develop and test metrics to quantitatively identify technological discontinuities in a knowledge network. We developed five metrics based on innovation theories and tested the metrics by a simulation model-based knowledge network and hypothetically designed discontinuity. The designed discontinuity is modeled as a node which combines two different knowledge streams and whose knowledge is dominantly persistent in the knowledge network. The performances of the proposed metrics were evaluated by how well the metrics can distinguish the designed discontinuity from other nodes on the knowledge network. The simulation results show that the persistence times # of converging main paths provides the best performance in identifying the designed discontinuity: the designed discontinuity was identified as one of the top 3 patents with 96~99% probability by Metric 5 and it is, according to the size of a domain, 12~34% better than the performance of the second best metric. Beyond the simulation ...

  13. Welfare Landscape and Communities

    DEFF Research Database (Denmark)

    Braae, Ellen Marie


    Danish housing developments of the post-war era were a cornerstone in the implementation of the welfare vision and the overall urban and landscape planning in the post-war period. The new city was a horizontal city and – as it will be my primary ambition to show – a green and landscape-like city....... The landscape came, in Denmark, to play a prominent role and became synonymous with ‘The Good Life’, but it also presented a number of moral imperatives. The article concerns how communities and community feelings found their expression in the Danish ‘welfare landscapes’....

  14. Discontinuity minimization for omnidirectional video projections (United States)

    Alshina, Elena; Zakharchenko, Vladyslav


    Advances in display technologies both for head mounted devices and television panels demand resolution increase beyond 4K for source signal in virtual reality video streaming applications. This poses a problem of content delivery trough a bandwidth limited distribution networks. Considering a fact that source signal covers entire surrounding space investigation reviled that compression efficiency may fluctuate 40% in average depending on origin selection at the conversion stage from 3D space to 2D projection. Based on these knowledge the origin selection algorithm for video compression applications has been proposed. Using discontinuity entropy minimization function projection origin rotation may be defined to provide optimal compression results. Outcome of this research may be applied across various video compression solutions for omnidirectional content.

  15. Discontinuity and complexity in nonlinear physical systems

    CERN Document Server

    Baleanu, Dumitru; Luo, Albert


    This unique book explores recent developments in experimental research in this broad field, organized in four distinct sections. Part I introduces the reader to the fractional dynamics and Lie group analysis for nonlinear partial differential equations. Part II covers chaos and complexity in nonlinear Hamiltonian systems, important to understand the resonance interactions in nonlinear dynamical systems, such as Tsunami waves and wildfire propagations; as well as Lev flights in chaotic trajectories, dynamical system synchronization and DNA information complexity analysis. Part III examines chaos and periodic motions in discontinuous dynamical systems, extensively present in a range of systems, including piecewise linear systems, vibro-impact systems and drilling systems in engineering. And in Part IV, engineering and financial nonlinearity are discussed. The mechanism of shock wave with saddle-node bifurcation and rotating disk stability will be presented, and the financial nonlinear models will be discussed....

  16. A physician's guide to discontinuing benzodiazepine therapy. (United States)

    DuPont, R L


    Practicing physicians need to have practical techniques to help patients who want to stop using benzodiazepines. I have developed three approaches that usually work. The first, and most widely applicable, is gradually reducing the dose without adding any other medicine. Failing this, use one of the following two approaches, occasionally combining them: switch to a longer-acting, cross-tolerant medication (usually clonazepam or phenobarbital) or use medications to suppress the withdrawal symptoms, usually carbamazepine, propranolol, or clonidine. If this fails, use inpatient detoxification. Chemically dependent patients, including those abusing alcohol and taking higher than recommended doses of sedative-hypnotics, require special care during discontinuation. Aftercare is important for all long-term benzodiazepine users if they are to remain drug-free and live relatively comfortable lives. PMID:1971976

  17. A physician's guide to discontinuing benzodiazepine therapy. (United States)

    DuPont, R L


    Practicing physicians need to have practical techniques to help patients who want to stop using benzodiazepines. I have developed three approaches that usually work. The first, and most widely applicable, is gradually reducing the dose without adding any other medicine. Failing this, use one of the following two approaches, occasionally combining them: switch to a longer-acting, cross-tolerant medication (usually clonazepam or phenobarbital) or use medications to suppress the withdrawal symptoms, usually carbamazepine, propranolol, or clonidine. If this fails, use inpatient detoxification. Chemically dependent patients, including those abusing alcohol and taking higher than recommended doses of sedative-hypnotics, require special care during discontinuation. Aftercare is important for all long-term benzodiazepine users if they are to remain drug-free and live relatively comfortable lives.

  18. Discontinuation of denosumab and associated fracture incidence

    DEFF Research Database (Denmark)

    Brown, Jacques P; Roux, Christian; Törring, Ove


    Osteoporosis is a chronic disease and requires long-term treatment with pharmacologic therapy to ensure sustained anti-fracture benefit. Denosumab reduced the risk for new vertebral, nonvertebral, and hip fractures over 36 months in the FREEDOM trial. While discontinuation of denosumab has been...... associated with transient increases in bone remodeling and declines in bone mineral density (BMD), the effect on fracture risk during treatment cessation is not as well characterized. To understand the fracture incidence between treatment groups after cessation of investigational product, we evaluated...... of 797 subjects (470 placebo, 327 denosumab), who were evaluable during the off-treatment period, showed similar baseline characteristics for age, prevalent fracture, and lumbar spine and total hip BMD T-scores. During treatment, more placebo-treated subjects as compared with denosumab-treated subjects...

  19. Bayesian methods for discontinuity detection in climate model predictions.

    Energy Technology Data Exchange (ETDEWEB)

    Safta, Cosmin; Debusschere, Bert J.; Najm, Habib N.; Sargsyan, Khachik


    Discontinuity detection is an important component in many fields: Image recognition, Digital signal processing, and Climate change research. Current methods shortcomings are: Restricted to one- or two-dimensional setting, Require uniformly spaced and/or dense input data, and Give deterministic answers without quantifying the uncertainty. Spectral methods for Uncertainty Quantification with global, smooth bases are challenged by discontinuities in model simulation results. Domain decomposition reduces the impact of nonlinearities and discontinuities. However, while gaining more smoothness in each subdomain, the current domain refinement methods require prohibitively many simulations. Therefore, detecting discontinuities up front and refining accordingly provides huge improvement to the current methodologies.

  20. Analysis of Waveguide Junction Discontinuities Using Finite Element Method (United States)

    Deshpande, Manohar D.


    A Finite Element Method (FEM) is presented to determine reflection and transmission coefficients of rectangular waveguide junction discontinuities. An H-plane discontinuity, an E-plane ridge discontinuity, and a step discontinuity in a concentric rectangular waveguide junction are analyzed using the FEM procedure. Also, reflection and transmission coefficients due to presence of a gap between two sections of a rectangular waveguide are determined using the FEM. The numerical results obtained by the present method are in excellent agreement with the earlier published results. The numerical results obtained by the FEM are compared with the numerical results obtained using the Mode Matching Method (MMM) and also with the measured data.

  1. Landscape metrics, scales of resolution (United States)

    Samuel A. Cushman; Kevin McGarigal


    Effective implementation of the "multiple path" approach to managing green landscapes depends fundamentally on rigorous quantification of the composition and structure of the landscapes of concern at present, modelling landscape structure trajectories under alternative management paths, and monitoring landscape structure into the future to confirm...

  2. Landscape genetics and limiting factors (United States)

    Samuel A. Cushman; Andrew J. Shirk; Erin L. Landguth


    Population connectivity is mediated by the movement of organisms or propagules through landscapes. However, little is known about how variation in the pattern of landscape mosaics affects the detectability of landscape genetic relationships. The goal of this paper is to explore the impacts of limiting factors on landscape genetic processes using simulation...

  3. Science of landscape restoration

    CSIR Research Space (South Africa)

    De Wet, Benita


    Full Text Available or email bdewet@ The science of landscape restoration Over the last two decades the ecological restoration of industrial land has developed into a specialist science combined with highly sophisticated management activities. A prime...

  4. Enhancement Through Landscaping. (United States)

    Lindley, Charles


    Landscaping can make the school environment more attractive, thus encouraging students' intellectual, emotional, and physical development. Guidelines are offered for comprehensive site planning, tree and plant selection, and grounds maintenance. (MLF)

  5. The Anti-Landscape

    DEFF Research Database (Denmark)

    There have always been some uninhabitable places, but in the last century human beings have produced many more of them. These anti-landscapes have proliferated to include the sandy wastes of what was once the Aral Sea, severely polluted irrigated lands, open pit mines, blighted nuclear zones......, coastal areas inundated by rising seas, and many others. The Anti-Landscape examines the emergence of such sites, how they have been understood, and how some of them have been recovered for habitation. The anti-landscape refers both to artistic and literary representations and to specific places...... humanities. The Anti-Landscape provides an interdisciplinary approach that moves beyond the false duality of nature vs. culture, and beyond diagnosis and complaint to the recuperation of damaged sites into our complex heritage. Collection of essays based on a conference held at SDU in 2011....

  6. Landscape Water Budget Tool (United States)

    WaterSense created the Water Budget Tool as one option to help builders, landscape professionals, and irrigation professionals certified by a WaterSense labeled program meet the criteria specified in the WaterSense New Home Specification.

  7. Eco-Landscape Design

    National Research Council Canada - National Science Library

    Flannery, John A; Smith, Karen M


    .... The effects of drought, melting polar ice and increased incidences of extreme weather events will impact on the diverse landscapes of the earth and a human population predicted to be 9 billion...

  8. Condensed landscape experience

    DEFF Research Database (Denmark)

    Earon, Ofri


    ‘Re-thinking interaction between landscape and urban buildings’ participates in an interdisciplinary discourse about the theoretical and practical advantages of openly juxtaposing landscape and architecture without having one more advanced in importance. Recently, the greenification of buildings...... is becoming a standard in contemporary architecture. Merging architecture and landscape has turned into a principle for an ecological / sustainable architecture. Yet, my aspiration is to achieve a wider interaction involving an application of a wider range of perspectives, such as: urban identity, social...... demands, quality of space, mixture of functions, urban complexity, public life and cultural heritage. In order to launch such an approach, an understanding of the spatial, social and environmental significance of a radical re-thinking of relationships between architecture and landscape is necessary...

  9. PNW Hydrologic Landscape Class (United States)

    U.S. Environmental Protection Agency — Work has been done to expand the hydrologic landscapes (HLs) concept and to develop an approach for using it to address streamflow vulnerability from climate change....

  10. Principles of landscape architecture


    Nijhuis, S.


    The Department of Urbanism at the Faculty of Architecture and Built Environment, TU Delft considers urbanism as a planning and design oriented activity towards urban and rural landscapes. It aims to enhance, restore or create landscapes from a perspective of sustainable development, so as to guide, harmonise and shape changes which are brought about by social, economic and environmental processes. In this respect we can consider urbanism as an object or goal-oriented interdisciplinary approac...

  11. Villages in landscapes

    DEFF Research Database (Denmark)

    Møller, Jørgen


    , and the physical appearance of many villages and detached farms can at best be characterized as shockingly inferior. It can be argued that the Danish society has grossly omitted to take care of the largest and most important part of its cultural heritage in the Danish landscape; 6-7,000 large and small villages...... dispersed in the Danish cultural landscape.These villages are crucial to the future of rural areas and are normally neglected....

  12. Discontinuation of Buprenorphine Maintenance Therapy: Perspectives and Outcomes (United States)

    Bentzley, Brandon S.; Barth, Kelly S.; Back, Sudie E.; Book, Sarah W.


    Buprenorphine maintenance therapy (BMT) is increasingly the preferred opioid maintenance agent due to its reduced toxicity and availability in an office-based setting in the United States. Although BMT has been shown to be highly efficacious, it is often discontinued soon after initiation. No current systematic review has yet investigated providers’ or patients’ reasons for BMT discontinuation or the outcomes that follow. Hence, provider and patient perspectives associated with BMT discontinuation after a period of stable buprenorphine maintenance and the resultant outcomes were systematically reviewed with specific emphasis on pre-buprenorphine-taper parameters predictive of relapse following BMT discontinuation. Few identified studies address provider or patient perspectives associated with buprenorphine discontinuation. Within the studies reviewed providers with residency training in BMT were more likely to favor long term BMT instead of detoxification, and providers were likely to consider BMT discontinuation in the face of medication misuse. Patients often desired to remain on BMT because of fear of relapse to illicit opioid use if they were to discontinue BMT. The majority of patients who discontinued BMT did so involuntarily, often due to failure to follow strict program requirements, and 1 month following discontinuation, rates of relapse to illicit opioid use exceeded 50% in every study reviewed. Only lower buprenorphine maintenance dose, which may be a marker for attenuated addiction severity, predicted better outcomes across studies. Relaxed BMT program requirements and frequent counsel on the high probability of relapse if BMT is discontinued may improve retention in treatment and prevent the relapse to illicit opioid use that is likely to follow BMT discontinuation. PMID:25601365

  13. A nonlinear filter for high order discontinuous Galerkin discretizations with discontinuity resolution within the cell (United States)

    Panourgias, Konstantinos T.; Ekaterinaris, John A.


    The nonlinear filter introduced by Yee et al. (1999) [27] and extensively used in the development of low dissipative well-balanced high order accurate finite-difference schemes is adapted to the finite element context of discontinuous Galerkin (DG) discretizations. The filter operator is constructed in the canonical computational domain for the standard cubical element where it is applied to the computed conservative variables in a direction per direction basis. Filtering becomes possible for all element types in unstructured meshes using collapsed coordinate transformations. The performance of the proposed nonlinear filter for DG discretizations is demonstrated and evaluated for different orders of expansions for one-dimensional and multidimensional problems with exact solutions. It is shown that for higher order discretizations discontinuity resolution within the cell is achieved and the design order of accuracy is preserved. The filter is applied for a number of standard inviscid flow test problems including strong shocks interactions to demonstrate that the proposed dissipative mechanism for DG discretizations yields superior results compared to the results obtained with the total variation bounded (TVB) limiter and high-order hierarchical limiting. The proposed approach is suitable for p-adaptivity in order to locally enhance resolution of three-dimensional flow simulations that include discontinuities and complex flow features.

  14. Discontinuation of statins among patients with type 2 diabetes

    NARCIS (Netherlands)

    Lamberts, E.J.F.; Nijpels, G.; Welschen, L.M.C.; Hugtenburg, J.G.; Dekker, J.M.; Souverein, P.C.; Bouvy, M.L.


    Background: Statins play an important role in the prevention of cardiovascular disease in type 2 diabetes. Several studies have reported low adherence with statins among patients with type 2 diabetes. Studies comparing discontinuation of statins compared with discontinuation of oral anti-diabetics

  15. 27 CFR 44.161 - Discontinuance of operations. (United States)


    ... Operations § 44.161 Discontinuance of operations. Every export warehouse proprietor who desires to discontinue operations and close out his warehouse shall dispose of all cigars, cigarettes, and cigarette... operations. 44.161 Section 44.161 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE...

  16. Discontinuities in Early Development of the Understanding of Physical Causality (United States)

    Aschersleben, Gisa; Henning, Anne; Daum, Moritz M.


    Research on early physical reasoning has shown surprising discontinuities in developmental trajectories. Infants possess some skills that seem to disappear and then re-emerge in childhood. It has been suggested that prediction skills required in search tasks might cause these discontinuities (Keen, 2003). We tested 3.5- to 5-year-olds'…

  17. Enacting discontinuity-what's useful and what's cumbersome

    NARCIS (Netherlands)

    Stegmaier, Peter


    In this paper, I will review various empirical and theoretical sets of conditions and strategies under which active and purposeful discontinuity appears accomplishable. More abrupt and more incremental processes of discontinuation will be distinguished, as well as how they are linked to different

  18. 38 CFR 8.17 - Discontinuance of premium waiver. (United States)


    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Discontinuance of premium waiver. 8.17 Section 8.17 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS NATIONAL SERVICE LIFE INSURANCE Premium Waivers and Total Disability § 8.17 Discontinuance of premium waiver. (a) The Secretary may require proof of...

  19. Double discontinuities at the magnetotail plasma sheet-lobe boundary

    Directory of Open Access Journals (Sweden)

    Y. C. Whang

    Full Text Available A double discontinuity is a compound structure composed of a slow shock layer and an adjoining rotational discontinuity layer on the postshock side. We use high-resolution data from Geotail and Wind spacecraft to examine the interior structure within the finite thickness of the discontinuity at the plasma sheet-lobe boundary and found that recognizable MHD structures at the boundary can be stand-alone slow shocks or double discontinuities. The plasma density increases significantly and the magnetic field intensity decreases significantly across the interior of the slow shock layer. Through the rotational layer, the magnetic field rotates about the normal direction of the shock surface, as the plasma density and the magnetic field intensity remain nearly unchanged. The rotational angle can vary over a wide range. We notice that the observations of double discontinuities are no less frequent than the observations of stand-alone slow shocks. Identification of slow shocks and double discontinuities infers that plasma and magnetic field lines continuously move across the boundary surface from the lobe into the plasma sheet, and there is a conversion of magnetic field energy into plasma thermal energy through the slow shock layer. The double discontinuities also allows for a rapid rotation of the postshock magnetic field lines immediately behind the shock layer to accommodate the environment of the MHD flow in the plasma sheet region.

    Key words. Magnetospheric physics (plasma sheet Space plasma physics (discontinuities; shock waves

  20. 27 CFR 21.3 - Stocks of discontinued formulas. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Stocks of discontinued..., DEPARTMENT OF THE TREASURY LIQUORS FORMULAS FOR DENATURED ALCOHOL AND RUM General Provisions § 21.3 Stocks of discontinued formulas. Denaturers, or specially denatured spirits dealers or users, having on hand stocks of...

  1. Discontinuous pn-heterojunction for organic thin film transistors

    NARCIS (Netherlands)

    Cho, B.; Yu, S.H.; Kim, M.; Lee, M.H.; Huh, W.; Lee, J.; Kim, J.; Cho, J.H.; Lee, J.Y.; Song, Y.J.; Kang, M.S.


    Utilization of discontinuous pn-oragnic heterojunction is introduced as a versatile method to improve charge transport in organic thin film transistors (OTFTs). The method is demonstrated by depositing n-type dioctyl perylene tetracarboxylic diimide (PTCDI-C8) discontinuously onto base p-type

  2. [Treatment methods for discontinuation of long-term benzodiazepine use

    NARCIS (Netherlands)

    Oude Voshaar, R.C.; Gorgels, W.J.M.J.; Mol, A.J.J.; Couvée, J.E.; Balkom, A.J.L.M. van; Zitman, F.G.


    Treatment strategies for discontinuing long-term benzodiazepine usage can be divided into minimal interventions and gradual discontinuation programs. Minimal interventions invite patients to quit their long-term benzodiazepine usage on their own by making them aware of the adverse effects. This type

  3. Semiotics in landscape design

    Directory of Open Access Journals (Sweden)

    Karsten Jorgensen


    Full Text Available This paper claims that concepts of language can help us create better and more relevant landscape design. It is based on research undertaken by Karsten Jørgensen (1989, and subsequent studies carried out at the department of Land Use and Landscape Planning at the Agricultural University in Norway. The 'signs' that constitute the design language are categorised using the analytical vocabulary of landscape design; for example, elements, materials, effects and shapes. Studies of these signs are based on elements of semiotics and cognitive science, especially the Umwelt-theories developed by Jakob von Uexküll (Hoffmeyer 1994. We are constantly exposed to numerous signs of different kinds. Everywhere in society we see signs around us; for example, traffic signs, advertising signs and logos. It is therefore relevant to introduce the term 'semiosphere' in order to focus on the significance of semiosis at all levels of activity in the world, from cellular activities, to complex systems of development such as those found in a population. This study focuses on the semantic aspects of landscape architecture. In explaining the meaning of a statement, it is useful to have a set of rules or 'codes' to correlate a specific expression with a specific interpretation. These codes may be based on conventions, or on similarity between or stylisation of objects, such as natural or cultural landscapes. In any case, they are based on the interpreter's language and 'mind-structure'. At a general level, it is only possible to study sign content. To analyse meaning in landscape design you have to look at the context; for example, the overall composition of a garden or park and the situation, which includes the interpreter's cultural background, their experiences and so on. In other words, you have to analyse a specific case to be able to speak reasonably about meaning in landscape (designs.

  4. New infrastructures, new landscapes

    Directory of Open Access Journals (Sweden)

    Chiara Nifosì


    Full Text Available New infrastructures, new landscapes AbstractThe paper will discuss one recent Italian project that share a common background: the relevance of the existing maritime landscape as a non negotiable value. The studies will be discussed in details a feasibility study for the new port in Monfalcone. National infrastructural policies emphasize competitiveness and connection as a central issue incultural, economic and political development of communities . Based on networks and system development along passageways that make up the European infrastructural armor; the two are considered at the meantime as cause and effect of "territorialisation”. These two views are obviously mutually dependent. It's hard to think about a strong attractiveness out of the network, and to be part of the latter encourages competitiveness. Nonetheless this has proved to be conflictual when landscape values and the related attractiveness are considered.The presented case study project, is pursuing the ambition to promote a new approach in realizing large infrastructures; its double role is to improve connectivity and to generate lasting and positive impact on the local regions. It deal with issues of inter-modality and the construction of nodes and lines which connects Europe, and its markets.Reverting the usual approach which consider landscape project as as a way to mitigate or to compensate for the infrastructure, the goal is to succeed in realizing large infrastructural works by conceiving them as an occasion to reinterpret a region or, as extraordinary opportunities, to build new landscapes.The strategy proposed consists in achieving structural images based on the reinforcement of the environmental and historical-landscape systems. Starting from the reinterpretation of local maritime context and resources it is possible not just to preserve the attractiveness of a specific landscape but also to conceive infrastructure in a more efficient way. 

  5. European landscape architecture and territorial strategies for water landscapes

    DEFF Research Database (Denmark)

    Diedrich, Lisa Babette


    This article sums up the author’s lecture at the 2009 Sydney Resilient Water Landscapes Symposium and presents a series of realized or planned European landscape architectural and urbanistic projects on water landscapes taken from the recently published book On Site/ Landscape Architecture Europe...... and accompanying reflections. The hypothesis is that further scientific research can help defining weaknesses and strengths of the existing water landscape designs in terms of resilience, extract principles and tools, improve the weak ones and communicate the strong ones and develop general quality criteria...... and tools for future resilient water landscapes....

  6. Geomorpho-Landscapes (United States)

    Farabollini, Piero; Lugeri, Francesca; Amadio, Vittorio


    Landscape is the object of human perceptions, being the image of spatial organization of elements and structures: mankind lives the first approach with the environment, viewing and feeling the landscape. Many definitions of landscape have been given over time: in this case we refer to the Landscape defined as the result of interaction among physical, biotic and anthropic phenomena acting in a different spatial-temporal scale (Foreman & Godron) Following an Aristotelic approach in studying nature, we can assert that " Shape is synthesis": so it is possible to read the land features as the expression of the endogenous and exogenous processes that mould earth surfaces; moreover, Landscape is the result of the interaction of natural and cultural components, and conditions the spatial-temporal development of a region. The study of the Landscape offers results useful in order to promote sustainable development, ecotourism, enhancement of natural and cultural heritage, popularization of the scientific knowledge. In Italy, a very important GIS-based tool to represent the territory is the "Carta della Natura" ("Map of Nature", presently coordinated by the ISPRA) that aims at assessing the state of the whole Italian territory, analyzing Landscape. The methodology follows a holistic approach, taking into consideration all the components of a landscape and then integrating the information. Each individual landscape, studied at different scales, shows distinctive elements: structural, which depend on physical form and specific spatial organization; functional, which depend on relationships created between biotic and abiotic elements, and dynamic, which depend on the successive evolution of the structure. The identification of the landscape units, recognized at different scales of analysis, allows an evaluation of the state of the land, referring to the dual risk/resource which characterizes the Italian country. An interesting opportunity is to discover those areas of unusual

  7. Discontinuous Galerkin algorithms for fully kinetic plasmas (United States)

    Juno, J.; Hakim, A.; TenBarge, J.; Shi, E.; Dorland, W.


    We present a new algorithm for the discretization of the non-relativistic Vlasov-Maxwell system of equations for the study of plasmas in the kinetic regime. Using the discontinuous Galerkin finite element method for the spatial discretization, we obtain a high order accurate solution for the plasma's distribution function. Time stepping for the distribution function is done explicitly with a third order strong-stability preserving Runge-Kutta method. Since the Vlasov equation in the Vlasov-Maxwell system is a high dimensional transport equation, up to six dimensions plus time, we take special care to note various features we have implemented to reduce the cost while maintaining the integrity of the solution, including the use of a reduced high-order basis set. A series of benchmarks, from simple wave and shock calculations, to a five dimensional turbulence simulation, are presented to verify the efficacy of our set of numerical methods, as well as demonstrate the power of the implemented features.

  8. Airborne electromagnetic imaging of discontinuous permafrost (United States)

    Minsley, B.J.; Abraham, J.D.; Smith, B.D.; Cannia, J.C.; Voss, C.I.; Jorgenson, M.T.; Walvoord, Michelle Ann; Wylie, B.K.; Anderson, L.; Ball, L.B.; Deszcz-Pan, M.; Wellman, T.P.; Ager, T.A.


    The evolution of permafrost in cold regions is inextricably connected to hydrogeologic processes, climate, and ecosystems. Permafrost thawing has been linked to changes in wetland and lake areas, alteration of the groundwater contribution to streamflow, carbon release, and increased fire frequency. But detailed knowledge about the dynamic state of permafrost in relation to surface and groundwater systems remains an enigma. Here, we present the results of a pioneering ∼1,800 line-kilometer airborne electromagnetic survey that shows sediments deposited over the past ∼4 million years and the configuration of permafrost to depths of ∼100 meters in the Yukon Flats area near Fort Yukon, Alaska. The Yukon Flats is near the boundary between continuous permafrost to the north and discontinuous permafrost to the south, making it an important location for examining permafrost dynamics. Our results not only provide a detailed snapshot of the present-day configuration of permafrost, but they also expose previously unseen details about potential surface – groundwater connections and the thermal legacy of surface water features that has been recorded in the permafrost over the past ∼1,000 years. This work will be a critical baseline for future permafrost studies aimed at exploring the connections between hydrogeologic, climatic, and ecological processes, and has significant implications for the stewardship of Arctic environments.

  9. Discontinuous college enrollment: associations with substance use and mental health. (United States)

    Arria, Amelia M; Caldeira, Kimberly M; Vincent, Kathryn B; Winick, Emily R; Baron, Rebecca A; O'Grady, Kevin E


    This study examined the prospective relationship of substance use and mental health problems with risk of discontinuous enrollment in college. Participants were 1,145 students at a large public university who were interviewed annually for four years beginning at college entry in 2004 (year 1). Discontinuous enrollment was defined as a gap in enrollment of one or more semesters during the first two years (early discontinuity) or the second two years (late discontinuity) versus continuous enrollment throughout all four years. Explanatory variables measured in year 1 were scores on the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory, childhood conduct problems, cannabis use, number of illicit drugs used, and alcohol consumption. In years 3 and 4, participants reported lifetime history of clinically diagnosed attention-deficit hyperactivity disorder, depression, and anxiety, including age at diagnosis. Multinomial logistic regression models were developed to evaluate the association between the independent variables and discontinuous enrollment while holding constant background characteristics. Higher BDI scores predicted early discontinuity but not late discontinuity, whereas cannabis and alcohol use predicted only late discontinuity. Receiving a depression diagnosis during college was associated with both early and late discontinuity. Self-reported precollege diagnoses were not related to discontinuous enrollment once background characteristics were taken into account. Students who experience depressive symptoms or seek treatment for depression during college might be at risk of interruptions in their college enrollment. Cannabis use and heavy drinking appear to add to this risk. Students entering college with preexisting psychiatric diagnoses are not necessarily at risk of enrollment interruptions.

  10. High-Resolution Global Modeling of the Effects of Subgrid-Scale Clouds and Turbulence on Precipitating Cloud Systems

    Energy Technology Data Exchange (ETDEWEB)

    Bogenschutz, Peter [National Center for Atmospheric Research, Boulder, CO (United States); Moeng, Chin-Hoh [National Center for Atmospheric Research, Boulder, CO (United States)


    The PI’s at the National Center for Atmospheric Research (NCAR), Chin-Hoh Moeng and Peter Bogenschutz, have primarily focused their time on the implementation of the Simplified-Higher Order Turbulence Closure (SHOC; Bogenschutz and Krueger 2013) to the Multi-scale Modeling Framework (MMF) global model and testing of SHOC on deep convective cloud regimes.

  11. Large Eddy Simulation of an SD7003 Airfoil: Effects of Reynolds number and Subgrid-scale modeling

    DEFF Research Database (Denmark)

    Sarlak Chivaee, Hamid


    This paper presents results of a series of numerical simulations in order to study aerodynamic characteristics of the low Reynolds number Selig-Donovan airfoil, SD7003. Large Eddy Simulation (LES) technique is used for all computations at chord-based Reynolds numbers 10,000, 24,000 and 60...

  12. Effect of reactions in small eddies on biomass gasification with eddy dissipation concept - Sub-grid scale reaction model. (United States)

    Chen, Juhui; Yin, Weijie; Wang, Shuai; Meng, Cheng; Li, Jiuru; Qin, Bai; Yu, Guangbin


    Large-eddy simulation (LES) approach is used for gas turbulence, and eddy dissipation concept (EDC)-sub-grid scale (SGS) reaction model is employed for reactions in small eddies. The simulated gas molar fractions are in better agreement with experimental data with EDC-SGS reaction model. The effect of reactions in small eddies on biomass gasification is emphatically analyzed with EDC-SGS reaction model. The distributions of the SGS reaction rates which represent the reactions in small eddies with particles concentration and temperature are analyzed. The distributions of SGS reaction rates have the similar trend with those of total reactions rates and the values account for about 15% of the total reactions rates. The heterogeneous reaction rates with EDC-SGS reaction model are also improved during the biomass gasification process in bubbling fluidized bed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Modeling lightning-NOx chemistry on a sub-grid scale in a global chemical transport model

    Directory of Open Access Journals (Sweden)

    A. Gressent


    Full Text Available For the first time, a plume-in-grid approach is implemented in a chemical transport model (CTM to parameterize the effects of the nonlinear reactions occurring within high concentrated NOx plumes from lightning NOx emissions (LNOx in the upper troposphere. It is characterized by a set of parameters including the plume lifetime, the effective reaction rate constant related to NOx–O3 chemical interactions, and the fractions of NOx conversion into HNO3 within the plume. Parameter estimates were made using the Dynamical Simple Model of Atmospheric Chemical Complexity (DSMACC box model, simple plume dispersion simulations, and the 3-D Meso-NH (non-hydrostatic mesoscale atmospheric model. In order to assess the impact of the LNOx plume approach on the NOx and O3 distributions on a large scale, simulations for the year 2006 were performed using the GEOS-Chem global model with a horizontal resolution of 2° × 2.5°. The implementation of the LNOx parameterization implies an NOx and O3 decrease on a large scale over the region characterized by a strong lightning activity (up to 25 and 8 %, respectively, over central Africa in July and a relative increase downwind of LNOx emissions (up to 18 and 2 % for NOx and O3, respectively, in July. The calculated variability in NOx and O3 mixing ratios around the mean value according to the known uncertainties in the parameter estimates is at a maximum over continental tropical regions with ΔNOx [−33.1, +29.7] ppt and ΔO3 [−1.56, +2.16] ppb, in January, and ΔNOx [−14.3, +21] ppt and ΔO3 [−1.18, +1.93] ppb, in July, mainly depending on the determination of the diffusion properties of the atmosphere and the initial NO mixing ratio injected by lightning. This approach allows us (i to reproduce a more realistic lightning NOx chemistry leading to better NOx and O3 distributions on the large scale and (ii to focus on other improvements to reduce remaining uncertainties from processes related to NOx chemistry in CTM.

  14. Sampling scheme on genetic structure of tree species in fragmented tropical dry forest: an evaluation from landscape genetic simulations (United States)

    Yessica Rico; Marie-Stephanie. Samain


    Investigating how genetic variation is distributed across the landscape is fundamental to inform forest conservation and restoration. Detecting spatial genetic discontinuities has value for defining management units, germplasm collection, and target sites for reforestation; however, inappropriate sampling schemes can misidentify patterns of genetic structure....

  15. Memorial landscape. Resilience through time and landscape


    Zhang, Hang


    The project is based on 2011 Tohoku earthquake and tsunami in Japan, and aims at building a landscape that evokes the memory of the past in Rikuzentakata area, and contributes to delaying the unpredictable tsunami in the future. The water: The proposal introduces a strategy of “changeable landscape” structure that move with water dynamics, using water itself as a design element to shape different memory gardens. The memory: The art of memory is in relation to the art of garden. The land’s mem...

  16. Multifunctional landscape practice and accessibility in manorial landscapes

    DEFF Research Database (Denmark)

    Brandt, Jesper; Svenningsen, Stig Roar; Christensen, Andreas Aagaard

    Structural development of modern productivistic agriculture characterized by marked specialization and increasing size of holdings are in general considered one of the main reasons behind a declining accessibility of landscape values within agricultural landscapes in most developed countries...... the trends at the other big modern specialized holdings. A historical tradition for access to the manorial landscape as an integrated part of the pre-capitalist way of landscape management at the manorial estates might play a certain role, but it is anticipated that this is being of less importance than...... the multifunctional landscape strategy supporting a certain public access. A study of this thesis is presented based on an analysis of multifunctionality, landscape development and accessibility in Danish Manorial landscapes and eventual linkages between their multifunctional landscape strategy, their history...

  17. Exploring biomolecular energy landscapes. (United States)

    Joseph, Jerelle A; Röder, Konstantin; Chakraborty, Debayan; Mantell, Rosemary G; Wales, David J


    The potential energy landscape perspective provides both a conceptual and a computational framework for predicting, understanding and designing molecular properties. In this Feature Article, we highlight some recent advances that greatly facilitate structure prediction and analysis of global thermodynamics and kinetics in proteins and nucleic acids. The geometry optimisation procedures, on which these calculations are based, can be accelerated significantly using local rigidification of selected degrees of freedom, and through implementations on graphics processing units. Results of progressive local rigidification are first summarised for trpzip1, including a systematic analysis of the heat capacity and rearrangement rates. Benchmarks for all the essential optimisation procedures are then provided for a variety of proteins. Applications are then illustrated from a study of how mutation affects the energy landscape for a coiled-coil protein, and for transitions in helix morphology for a DNA duplex. Both systems exhibit an intrinsically multifunnel landscape, with the potential to act as biomolecular switches.

  18. Landscapes of the Anthropocene

    DEFF Research Database (Denmark)

    Pawson, Eric; Christensen, Andreas Aagaard


    The purpose of this chapter is to explore the dramatic increase in the power of human agency over the environment through an analysis of landscape change. It discusses the processes that have shaped new landscapes in the capitalist world before focusing on one place that is characteristic...... since the 1840s, when indigenous forests were transformed into improved landscapes of sown grass. The chapter is shaped by a broad question. What can be learned from this place about the ways in which people have exercised and are coming to terms with what Gibson-Graham and Roelvink describe as our...... ‘gargantuan agency’ and ‘almost unbearable level of responsibility’ in the Anthropocene (2009, 321)? It concludes with a discussion of the concept of ‘middle landscapes’ as one means by which the planetary dominion of humanity might be tempered with a realization of its dependence on terrestrial ecosystems...

  19. Qualifying Urban Landscapes

    DEFF Research Database (Denmark)

    Clemmensen, Thomas Juel; Nielsen, Tom; Daugaard, Morten


    The article presents an attempt to develop alternatives to the dominant planning and design principles used in building and rebuilding the contemporary urban landscape. The basic idea is that the ‘forces of modernisation’ driving current development might result in a broader and more interesting...... for contemporary urban landscape design practice....... to the task of constructing and improving things. With this goal, a set of objectives based in important insights from recent urban theory are formulated constituting the normative spine of the analysis of a number of found situations as basis for formulating eight generic concepts of qualification...

  20. Digital landscapes of imagination

    Directory of Open Access Journals (Sweden)

    Starlight Vattano


    Full Text Available Urban landscapes that exist in the expression of an imaginative sequence define their shape through the digital representation. These hyperreal dimensions, combine imagination and representation as constituents a new reality, which follows the utopian, suprematist and constructivist theories, where the two-dimensional dynamics is transformed into an infinite space in which the imagination creates new forms. Although interpretations of the urban landscape film, put in place a correspondence between reality and virtuality, into the modeling of spatial movements, from which do not arise contraries, but only interdependencies. It is a particular type of representation that takes shape via the digital in motion and provides new tools for urban representation.

  1. Imagine A Collective Landscape

    Directory of Open Access Journals (Sweden)

    Manuela Silvia Campanini


    Full Text Available Iceland plays a key role in the circumpolar context. The research investigates the fields of both the icelandic cultural landscape perception and the icelandic cultural identity. It considers the book Ultima thule; or, a summer in Iceland and Ólafur Elíasson art works as two sides of a same medal: the Iceland on the brain concept (F. Burton. The transition from a cultural identity to a collective landscape identity is investigated analysing Imagine J. Lennon's song which inspired Yõko Ono's work art titled Imagine Peace Tower.

  2. Adaptive Finite Element Methods for Elliptic Problems with Discontinuous Coefficients

    KAUST Repository

    Bonito, Andrea


    Elliptic PDEs with discontinuous diffusion coefficients occur in application domains such as diffusions through porous media, electromagnetic field propagation on heterogeneous media, and diffusion processes on rough surfaces. The standard approach to numerically treating such problems using finite element methods is to assume that the discontinuities lie on the boundaries of the cells in the initial triangulation. However, this does not match applications where discontinuities occur on curves, surfaces, or manifolds, and could even be unknown beforehand. One of the obstacles to treating such discontinuity problems is that the usual perturbation theory for elliptic PDEs assumes bounds for the distortion of the coefficients in the L∞ norm and this in turn requires that the discontinuities are matched exactly when the coefficients are approximated. We present a new approach based on distortion of the coefficients in an Lq norm with q < ∞ which therefore does not require the exact matching of the discontinuities. We then use this new distortion theory to formulate new adaptive finite element methods (AFEMs) for such discontinuity problems. We show that such AFEMs are optimal in the sense of distortion versus number of computations, and report insightful numerical results supporting our analysis. © 2013 Societ y for Industrial and Applied Mathematics.

  3. Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib. (United States)

    Jain, Preetesh; Keating, Michael; Wierda, William; Estrov, Zeev; Ferrajoli, Alessandra; Jain, Nitin; George, Binsah; James, Danelle; Kantarjian, Hagop; Burger, Jan; O'Brien, Susan


    Ibrutinib is a Bruton tyrosine kinase inhibitor approved for the treatment of patients with relapsed refractory chronic lymphocytic leukemia (RR-CLL). We describe the characteristics, causes of discontinuation, and outcomes in patients who discontinued treatment with ibrutinib. One hundred twenty-seven patients were enrolled in various clinical trials of ibrutinib, with or without rituximab, at our center. Thirty-three (26%) patients have discontinued ibrutinib to date. The majority of those patients had high-risk features: 94% with unmutated immunoglobulin heavy chain variable gene rearrangement, 58% with del(17p) by fluorescence in situ hybridization, and 54% with a complex karyotype. Causes of discontinuation were disease transformation (7), progressive CLL (7), stem cell transplantation (3), adverse events (11), serious adverse events/deaths (3), and miscellaneous reasons (2). Twenty five patients (76%) died after discontinuing ibrutinib; the median overall survival was 3.1 months after discontinuation. Most patients with RR-CLL who discontinued ibrutinib early were difficult to treat and had poor outcomes. © 2015 by The American Society of Hematology.

  4. Predictors of premature discontinuation of treatment in multiple disease states

    Directory of Open Access Journals (Sweden)

    Eric Nantz


    Full Text Available Eric Nantz1, Hong Liu-Seifert2, Vladimir Skljarevski21Department of Statistics, Western Michigan University, Kalamazoo, MI, USA; 2Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USABackground: Premature discontinuation of treatment impacts outcomes of clinical practice. The traditional perception has been patient discontinuation is mainly driven by unwanted side effects. Systematic analysis of data from clinical trials across several disease states was performed to identify predictors of premature discontinuation during clinical interventions.Methods: A post hoc analysis was conducted on 22 randomized, double-blind, placebo-controlled clinical trials for treatment of fibromyalgia, diabetic peripheral neuropathic pain, major depressive disorder, and generalized anxiety disorder. Analyses were conducted on pooled data within each disease state.Results: Lack of early therapeutic response was a significant predictor of patient discontinuation in each disease state. Visit-wise changes in therapeutic response and severity of adverse events were also significant risk factors, with change in therapeutic response having a higher significance level in three disease states. Patients who discontinued due to adverse events had similar therapeutic responses as patients completing treatment.Conclusion: Contrary to the conventional belief that premature treatment discontinuation is primarily related to adverse events, our findings suggest lack of therapeutic response also plays a significant role in patient attrition. This research highlights the importance of systematic monitoring of therapeutic response in clinical practice as a measure to prevent patients’ discontinuation from pharmacological treatments.Keywords: attrition, depression, generalized anxiety disorder, fibromyalgia, therapeutic response, adverse event

  5. [Discontinuation of immunosuppressive and immunomodulatory drugs in connective tissue diseases]. (United States)

    Targońska-Stępniak, Bożena


    Remission in connective tissue diseases became a realistic goal of therapy nowadays. However, there is lack of recommendations on the management after achieving a remission. Chronic exposure to immunosuppressive or immunomodulatory drugs may be associated with adverse events, that is why temporal withdrawal or discontinuation of treatment is advisable. In patients with rheumatoid arthritis (RA) who achieve sustained remission lasting for 6-12 months, an attempt to withdraw biological disease modifying antirheumatic drugs (bDMARDs) may be considered. In most patients with established RA discontinuation of bDMARDs is accompanied by a disease flare, butthe risk of loss of good therapeutic response is lower in case of slowly tapering by expanding the interval between doses or reducing the dose of bDMARDs. Patients with early RA are more likely to have successful discontinuation of therapy. Discontinuation of conventional DMARDs (cDMARDs) is usually associated with a disease flare, that is why tapering of doses is advised rather than stopping cDMARDs. DMARDs free remission occurs relatively rare, more often in patients with seronegative RA and with early onset of modifying treatment. In lupus nephritis (LN) patients with persistent, long-term remission, progressive tapering of doses of immunosuppressive drugs and glucocorticoids is recommended, with treatment discontinuation as a goal. An attempt of treatment withdrawal may be taken in patients remaining in LN complete remission as a consequence of maintenance therapy for 3 years.The process of slow tapering of doses preceding discontinuation of drugs, may last several months. The therapy with antimalarial drugs may be helpful to maintain remission after the treatment discontinuation. There is few data on treatment discontinuation in patients with systemic lupus erythematosus (SLE) without kidney involvement. Immunosuppressive drugs withdrawal is usually performed in patients with stable serological and clinically

  6. Hydrologic landscape regions of Nevada (United States)

    U.S. Geological Survey, Department of the Interior — Hydrologic landscape regions group areas according to their similarity in landscape and climate characteristics. These characteristics represent variables assumed to...

  7. Landscape infrastructure : urbanism beyond engineering

    NARCIS (Netherlands)

    Bélanger, P.


    As ecology becomes the new engineering, the project of Landscape Infrastructure - a contemporary, synthetic alignment of the disciplines of landscape architecture, civil engineering and urban planning - is proposed here. Predominant challenges facing urban regions today are addressed, including

  8. Large sliding contact along branched discontinuities with X-FEM (United States)

    Siavelis, Maximilien; Guiton, Martin L. E.; Massin, Patrick; Moës, Nicolas


    The extended finite element method (X-FEM) has been developed to minimize requirements on the mesh in a problem with a displacement discontinuity. We present the development carried out to take advantage of the X-FEM approach in simplifying the meshing of complex 3D networks of discontinuities with junctions. Contact with large sliding along the branched discontinuities is discussed. Solutions are proposed and discussed to solve some matrix conditioning issues. Several examples are presented in this paper in order to prove the efficiency of the proposed approach.

  9. Mitochondrial DNA structure in North Africa reveals a genetic discontinuity in the Nile Valley. (United States)

    Fadhlaoui-Zid, Karima; Rodríguez-Botigué, Laura; Naoui, Nejib; Benammar-Elgaaied, Amel; Calafell, Francesc; Comas, David


    Human population movements in North Africa have been mostly restricted to an east-west direction due to the geographical barriers imposed by the Sahara Desert and the Mediterranean Sea. Although these barriers have not completely impeded human migrations, genetic studies have shown that an east-west genetic gradient exists. However, the lack of genetic information of certain geographical areas and the focus of some studies in parts of the North African landscape have limited the global view of the genetic pool of North African populations. To provide a global view of the North African genetic landscape and population structure, we have analyzed ∼2,300 North African mitochondrial DNA lineages (including 269 new sequences from Libya, in the first mtDNA study of the general Libyan population). Our results show a clinal distribution of certain haplogroups, some of them more frequent in Western (H, HV0, L1b, L3b, U6) or Eastern populations (L0a, R0a, N1b, I, J) that might be the result of human migrations from the Middle East, sub-Saharan Africa, and Europe. Despite this clinal pattern, a genetic discontinuity is found in the Libyan/Egyptian border, suggesting a differential gene flow in the Nile River Valley. Finally, frequency of the post-LGM subclades H1 and H3 is predominant in Libya within the H sequences, highlighting the magnitude of the LGM expansion in North Africa. Copyright © 2011 Wiley-Liss, Inc.

  10. A landscape analysis plan (United States)

    Nancy E. Fleenor


    A Landscape Analysis Plan (LAP) sets out broad guidelines for project development within boundaries of the Kings River Sustainable Forest Ecosystems Project. The plan must be a dynamic, living document, subject to change as new information arises over the course of this very long-term project (several decades). Two watersheds, each of 32,000 acres, were dedicated to...

  11. Landscape Designs for Schools. (United States)

    Taylor, Patricia

    This annotated bibliography includes summaries of 15 books and articles dealing with the topic of school landscape design, as well as a brief introduction that comments on recent trends in the field. Most of the publications cited are fairly recent; about two-thirds of them were published after 1970. Annotations range from approximately 125 to 250…

  12. Landscape as World Picture

    DEFF Research Database (Denmark)

    Wamberg, Jacob

    are taken as a testimony to how cosmos splits into a chaotic Mother Earth and an indestructible masculine heaven. Finally, Volume I demonstrates that the ancient landscape images' exclusion of traces of cultivation (e.g. fields, roads, hedges, fences) is the result of work-shyness, a longing for the Golden...

  13. Landscape Planning of Schoolyards (United States)

    Kopeva, A.; Khrapko, O.; Ivanova, O.


    The optimal landscape architecture planning of schoolyards allows for creation of favorable conditions for children personal development and physical fitness. The key principles of schoolyard landscape planning, same as for other areas intended for children, are as follows: establishment of a favorable microclimate, safety, aesthetic and educational environment. Green spaces play an essential role in this respect as they are essential to sanitary, hygienic, structural, and spatial planning performing decorative, artistic, cognitive, and educational functions in these areas. Various types of landscape plantings are used in school areas: borders, lawns, beds, vines, ornamental arrangements, and various potted plants. Children’s safety is the key principle when selecting a landscape design type and the plants’ range. Any allergenic, poisonous, thorny, strong-smelling or life-threatening plants are excluded. Plants on school grounds can serve as visual aids for studies. Drought-resistant, attractive, colorful, abundantly blooming plants with variable leaf texture are preferred. Ornamental trees and shrubs as well as perennials and annuals provide a broad plant range for school grounds.

  14. Diversity in Riparian Landscapes (United States)

    Thomas R. Crow; Matthew E. Baker; Burton V. Barnes


    Therefore, in this chapter we focus on ecosystem diversity, defined as the number, kind, and pattern of landscape and waterscape ecosystems in a specified area and the ecological processes that are associated with these patterns (Lapin and Barnes 1995). One can then characterize eeosysterns as to their composition, structure, and function -- the attributes Of...

  15. Qualifying Urban Landscapes

    DEFF Research Database (Denmark)

    Juel Clemmensen, Thomas; Daugaard, Morten; Nielsen, Tom

    This paper is based on a research project aimed at contributing to the qualification of the aesthetical value of the contemporary urban landscape. We see our work as part of a tradition within the architectural profession of making explorative projects, which combines analysis of the contemporary...

  16. Reprogramming the chromatin landscape

    DEFF Research Database (Denmark)

    Miranda, Tina B; Voss, Ty C; Sung, Myong-Hee


    , mechanistic details defining the cellular interactions between ER and GR are poorly understood. We investigated genome-wide binding profiles for ER and GR upon coactivation and characterized the status of the chromatin landscape. We describe a novel mechanism dictating the molecular interplay between ER...

  17. Complexity and valued landscapes (United States)

    Michael M. McCarthy


    The variable "complexity," or "diversity," has received a great deal of attention in recent research efforts concerned with visual resource management, including the identification of complexity as one of the primary evaluation measures. This paper describes research efforts that support the hypothesis that the landscapes we value are those with...

  18. Landscapes. Artists' Workshop Series. (United States)

    King, Penny; Roundhill, Clare

    This instructional resource, designed to be used by and with elementary level students, provides inspiration for landscape painting by presenting the work of six different artists. These include: "Fuji in Clear Weather" (Katsushika Hokusai, 1823-29); "The Tree of Life" (Gustav Klimt, c. 1905-1909); "The Waterlily…

  19. Landscape genetics [Chapter 17 (United States)

    Kevin S. McKelvey; Samuel A. Cushman; Michael K. Schwartz


    In reading this book, you have observed that the spatial data used in landscape ecology come from many sources and in many forms. For many organisms, these data take the form of presence or absence at a location, or numbers of individuals at that same location. For species such as trees, where huge size differences exist between individuals, indices such as basal area...

  20. Descriptive approaches to landscape analysis (United States)

    R. Burton Litton Jr.


    Descriptive landscape analyses include various procedures used to document visual/scenic resources. Historic and regional examples of landscape description represent desirable insight for contemporary professional inventory work. Routed and areal landscape inventories are discussed as basic tools. From them, qualitative and quantitative evaluations can be developed...

  1. Firewise Landscaping for Woodland Homes


    Close, David


    A home in a woodland setting is surrounded by flammable vegetation. Firewise landscaping can help you create a defensible space or buffer zone around your home. This publication details landscaping zones which should be used when planning for fire protections and rates common landscaping plants by flammability.

  2. Why do patients discontinue fertility treatment? A systematic review of reasons and predictors of discontinuation in fertility treatment (United States)

    Gameiro, S.; Boivin, J.; Peronace, L.; Verhaak, C.M.


    BACKGROUND Chances of achieving parenthood are high for couples who undergo fertility treatment. However, many choose to discontinue before conceiving. A systematic review was conducted to investigate patients' stated reasons for and predictors of discontinuation at five fertility treatment stages. METHODS Six databases were systematically searched. Search-terms referred to fertility treatment and discontinuation. Studies reporting on patients' stated reasons for or predictors of treatment discontinuation were included. A list of all reasons for discontinuation presented in each study was made, different categories of reasons were defined and the percentage of selections of each category was calculated. For each predictor, it was noted how many studies investigated it and how many found a positive and/or negative association with discontinuation. RESULTS The review included 22 studies that sampled 21 453 patients from eight countries. The most selected reasons for discontinuation were: postponement of treatment (39.18%, postponement of treatment or unknown 19.17%), physical and psychological burden (19.07%, psychological burden 14%, physical burden 6.32%), relational and personal problems (16.67%, personal reasons 9.27%, relational problems 8.83%), treatment rejection (13.23%) and organizational (11.68%) and clinic (7.71%) problems. Some reasons were common across stages (e.g. psychological burden). Others were stage-specific (e.g. treatment rejection during workup). None of the predictors reported were consistently associated with discontinuation. CONCLUSIONS Much longitudinal and theory led research is required to explain discontinuation. Meanwhile, treatment burden should be addressed by better care organization and support for patients. Patients should be well informed, have the opportunity to discuss values and worries about treatment and receive advice to decide about continuing treatment. PMID:22869759

  3. Geomorphology of anthropogenic landscapes (United States)

    Sofia, Giulia; Tarolli, Paolo


    The construction of urban areas and the development of road networks leave a significant signature on the Earth surface, providing a geomorphological evidence to support the idea that humans are nowadays a geomorphic agent having deep effects on the morphological organization of the landscape. The reconstruction or identification of anthropogenic topographies, therefore, provides a mechanism for quantifying anthropogenic changes to the landscape systems in the Anthropocene. Following this research line, the present study tests the effectiveness of a recently published topographic index, the Slope Local Length of Autocorrelation (SLLAC, Sofia et al. 2014) to portrait anthropogenic geomorphology, focusing in particular on road network density, and urban complexity (UCI). At first, the research considers the increasing of anthropic structures and the resulting changes in the SLLAC and in two derived parameters (mean SLLAC per km2 and SLLAC roughness, or Surface Peak Curvature -Spc). As a second step, considering the SLLAC derived indices, the anthropogenic geomorphology is automatically depicted using a k-means clustering algorithm. In general, the increasing of road network density or of the UCI is positively correlated to the mean SLLAC per km2, while the Spc is negatively correlated to the increasing of the anthropic structures. Areas presenting different road network organization are effectively captured considering multiple combinations of the defined parameters. Landscapes with small scattered towns, and a network with long roads in a dendritic shape (with hierarchical branching) are characterized simultaneously by high mean SLLAC and low Spc. Large and complex urban areas served by rectilinear networks with numerous short straight lines and right angles, have either a maximized mean SLLAC or a minimized Spc or both. In all cases, the anthropogenic landscape identified by the procedure is comparable to the ones identified manually from orthophoto, with the

  4. 23 CFR 752.4 - Landscape development. (United States)


    ... ROADSIDE DEVELOPMENT § 752.4 Landscape development. (a) Landscape development, which includes landscaping... landscaping and environmental design. (b) Landscape development should have provisions for plant establishment..., such as junkyard screening or urban landscaping projects. (c) In urban areas new and major...

  5. Prolonged effect of Rosiglitazone one year after discontinuation

    DEFF Research Database (Denmark)

    Gram-Kampmann, Eva-Marie; Olesen, Thomas Bastholm; Olsen, Michael Hecht


    Hypotese og formål: Rosiglitazone is a PPARγ-receptor agonist. It enhances glycemic control by increasing insulin sensitivity in fat- and muscle cells. This study addresses what to expect when discontinuing Rosiglitazone in type 2-diabetic patients who are also treated with insulin. Metoder......, Rosiglitazone and placebo-group had a significant weighloss after discontinuation of Rosiglitazone compared to the insulin, metformin and placebo-group (-3,9kg vs 0,1kg, pweight loss was also observed in the group treated with insulin, metformin and Rosiglitazone compared with the insulin......, metformin and placebo-group after discontinuation of Rosiglitazone (-1,6kg vs 0,1kg, p=0,034). Konklusion: A prolonged benficial effect in insulin sensitivity and a significant weight loss can be expected at least a year after discontinuation of Rosiglitazon in combination with insulin....

  6. The Audiometric and Mechanical Effects of Partial Ossicular Discontinuity (United States)

    Farahmand, Rosemary B.; Merchant, Gabrielle R.; Lookabaugh, Sarah A.; Röösli, Christof; Ulku, Cagatay H.; McKenna, Michael J.; de Venecia, Ronald K.; Halpin, Christopher F.; Rosowski, John J.; Nakajima, Hideko H.


    Objectives Ossicular discontinuity may be complete, with no contact between the disconnected ends, or partial, where normal contact at an ossicular joint or along a continuous bony segment of an ossicle is replaced by soft tissue or simply by contact of opposing bones. Complete ossicular discontinuity typically results in an audiometric pattern of a large, flat conductive hearing loss. In contrast, in cases where otomicroscopy reveals a normal external ear canal and tympanic membrane, high frequency conductive hearing loss has been proposed as an indicator of partial ossicular discontinuity. Nevertheless, the diagnostic utility of high-frequency conductive hearing loss has been limited due to gaps in previous research on the subject, and clinicians often assume that an audiogram showing high-frequency conductive hearing loss is flawed. This study aims to improve the diagnostic utility of high-frequency conductive hearing loss in cases of partial ossicular discontinuity by: (1) making use of a control population against which to compare the audiometry of partial ossicular discontinuity patients, and (2) examining the correlation between high-frequency conductive hearing loss and partial ossicular discontinuity under controlled experimental conditions on fresh cadaveric temporal bones. Furthermore, ear-canal measurements of umbo velocity and wideband acoustic immittance measurements were investigated to determine usefulness regarding diagnosis of ossicular discontinuity. Design We analyzed audiograms from 66 patients with either form of surgically-confirmed ossicular discontinuity and no confounding pathologies. We also analyzed umbo velocity (n=29) and power reflectance (n=12) measurements from a subset of these patients. Finally, we performed experiments on 6 fresh temporal bone specimens to study the differing mechanical effects of complete and partial discontinuity. The mechanical effects of these lesions were assessed via laser Doppler measurements of stapes

  7. Discontinuities, cross-scale patterns, and the organization of ecosystems (United States)

    Nash, Kirsty L.; Allen, Craig R.; Angeler, David G.; Barichievy, Chris; Eason, Tarsha; Garmestani, Ahjond S.; Graham, Nicholas A.J.; Granholm, Dean; Knutson, Melinda; Nelson, R. John; Nystrom, Magnus; Stow, Craig A.; Sandstrom, Shana M.


    Ecological structures and processes occur at specific spatiotemporal scales, and interactions that occur across multiple scales mediate scale-specific (e.g., individual, community, local, or regional) responses to disturbance. Despite the importance of scale, explicitly incorporating a multi-scale perspective into research and management actions remains a challenge. The discontinuity hypothesis provides a fertile avenue for addressing this problem by linking measureable proxies to inherent scales of structure within ecosystems. Here we outline the conceptual framework underlying discontinuities and review the evidence supporting the discontinuity hypothesis in ecological systems. Next we explore the utility of this approach for understanding cross-scale patterns and the organization of ecosystems by describing recent advances for examining nonlinear responses to disturbance and phenomena such as extinctions, invasions, and resilience. To stimulate new research, we present methods for performing discontinuity analysis, detail outstanding knowledge gaps, and discuss potential approaches for addressing these gaps.

  8. Discontinuous type of splenogonadal fusion syndrome with limb defects. (United States)

    Patre, Vivek; Netam, Satyabhuwan; Luka, Pankaj; Mandle, Hulesh


    Splenogonadal fusion is a rare congenital anomaly. We report a case of discontinuous type of splenogonadal fusion with congenital malformation. We focused here to avoid unnecessary orchidectomy by cementing the base of preoperative scrotal ultrasonography, for paratesticular masses.

  9. Discontinuous type of splenogonadal fusion syndrome with limb defects


    Vivek Patre; Satyabhuwan Netam; Pankaj Luka; Hulesh Mandle


    Splenogonadal fusion is a rare congenital anomaly. We report a case of discontinuous type of splenogonadal fusion with congenital malformation. We focused here to avoid unnecessary orchidectomy by cementing the base of preoperative scrotal ultrasonography, for paratesticular masses.

  10. Father's Labour Migration and Children's School Discontinuation in Rural Mozambique. (United States)

    Yabiku, Scott T; Agadjanian, Victor


    We examine how the discontinuation of schooling among left-behind children is related to multiple dimensions of male labor migration: the accumulation of migration experience, the timing of these migration experiences in the child's life course, and the economic success of the migration. Our setting is rural southern Mozambique, an impoverished area with massive male labor out-migration. Results show that fathers' economically successful labor migration is more beneficial for children's schooling than unsuccessful migration or non-migration. There are large differences, however, by gender: compared to sons of non-migrants, sons of migrant fathers (regardless of migration success) have lower rates of school discontinuation, while daughters of migrant fathers have rates of school discontinuation no different than daughters of non-migrants. Furthermore, accumulated labor migration across the child's life course is beneficial for boys' schooling, but not girls'. Remittances sent in the past year reduce the rate of discontinuation for sons, but not daughters.

  11. The derivative discontinuity of the exchange-correlation functional

    CERN Document Server

    Mori-Sánchez, Paula


    The derivative discontinuity is a key concept in electronic structure theory in general and density functional theory in particular. The electronic energy of a quantum system exhibits derivative discontinuities with respect to different degrees of freedom that are a consequence of the integer nature of electrons. The classical understanding refers to the derivative discontinuity of the total energy as a function of the total number of electrons ($N$), but it can also manifest at constant $N$. Examples are shown in models including several Hydrogen systems with varying numbers of electrons or nuclear charge ($Z$), as well as the 1-dimensional Hubbard model (1DHM). Two sides of the problem are investigated: first, the failure of currently used approximate exchange-correlation functionals in DFT and, second, the importance of the derivative discontinuity in the exact electronic structure of molecules, as revealed by full configuration interaction (FCI). Currently, all approximate functionals miss the derivative ...

  12. Clopidogrel discontinuation after myocardial infarction and risk of thrombosis

    DEFF Research Database (Denmark)

    Charlot, Mette; Nielsen, Lars Hougaard; Lindhardsen, Jesper


    The benefit of extending clopidogrel treatment beyond the 12-month period recommended in current guidelines after myocardial infarction (MI) is debated. We analysed the risk of adverse cardiovascular outcomes after discontinuation of 12 months of clopidogrel treatment....

  13. The Audiometric and Mechanical Effects of Partial Ossicular Discontinuity. (United States)

    Farahmand, Rosemary B; Merchant, Gabrielle R; Lookabaugh, Sarah A; Röösli, Christof; Ulku, Cagatay H; McKenna, Michael J; de Venecia, Ronald K; Halpin, Christopher F; Rosowski, John J; Nakajima, Hideko H


    Ossicular discontinuity may be complete, with no contact between the disconnected ends, or partial, where normal contact at an ossicular joint or along a continuous bony segment of an ossicle is replaced by soft tissue or simply by contact of opposing bones. Complete ossicular discontinuity typically results in an audiometric pattern of a large, flat conductive hearing loss. In contrast, in cases where otomicroscopy reveals a normal external ear canal and tympanic membrane, high-frequency conductive hearing loss has been proposed as an indicator of partial ossicular discontinuity. Nevertheless, the diagnostic utility of high-frequency conductive hearing loss has been limited due to gaps in previous research on the subject, and clinicians often assume that an audiogram showing high-frequency conductive hearing loss is flawed. This study aims to improve the diagnostic utility of high-frequency conductive hearing loss in cases of partial ossicular discontinuity by (1) making use of a control population against which to compare the audiometry of partial ossicular discontinuity patients and (2) examining the correlation between high-frequency conductive hearing loss and partial ossicular discontinuity under controlled experimental conditions on fresh cadaveric temporal bones. Furthermore, ear-canal measurements of umbo velocity and wideband acoustic immittance measurements were investigated to determine the usefulness regarding diagnosis of ossicular discontinuity. The authors analyzed audiograms from 66 patients with either form of surgically confirmed ossicular discontinuity and no confounding pathologies. The authors also analyzed umbo velocity (n = 29) and power reflectance (n = 12) measurements from a subset of these patients. Finally, the authors performed experiments on six fresh temporal bone specimens to study the differing mechanical effects of complete and partial discontinuity. The mechanical effects of these lesions were assessed via laser Doppler

  14. Calculation of Accurate Hexagonal Discontinuity Factors for PARCS

    Energy Technology Data Exchange (ETDEWEB)

    Pounders. J., Bandini, B. R. , Xu, Y, and Downar, T. J.


    In this study we derive a methodology for calculating discontinuity factors consistent with the Triangle-based Polynomial Expansion Nodal (TPEN) method implemented in PARCS for hexagonal reactor geometries. The accuracy of coarse-mesh nodal methods is greatly enhanced by permitting flux discontinuities at node boundaries, but the practice of calculating discontinuity factors from infinite-medium (zero-current) single bundle calculations may not be sufficiently accurate for more challenging problems in which there is a large amount of internodal neutron streaming. The authors therefore derive a TPEN-based method for calculating discontinuity factors that are exact with respect to generalized equivalence theory. The method is validated by reproducing the reference solution for a small hexagonal core.

  15. Continued versus discontinued oxytocin stimulation, protocol of an rct

    DEFF Research Database (Denmark)

    Boie, Sidsel; Glavind, Julie; Uldbjerg, Niels

    outcome Caesarean delivery Secondary outcomes Postpartum haemorrhage Duration of labour Instrumental delivery Neonatal morbidity Birth experience Breastfeeding Results: Results are expected in 2018. Conclusions: This is the first double-blind RCT on discontinuation or continuation of oxytocin stimulation...

  16. Modelling discontinuous well log signal to identify lithological ...

    Indian Academy of Sciences (India)

    Identification of sharp and discontinuous lithological boundaries from well log signal stemming fromheterogeneous subsurface structures assumes a special significance in geo-exploration studies. Well logdata acquired from various geological settings generally display nonstationary/nonlinear characteristicswith varying ...

  17. Adjunctive treatment of benzodiazepine discontinuation syndromes: a review. (United States)

    Roy-Byrne, P P; Sullivan, M D; Cowley, D S; Ries, R K


    The variety of pharmacologic and psychotherapeutic approaches to facilitate benzodiazepine discontinuation are reviewed. Strategies to attenuate physiologic withdrawal with clonidine, propranolol and carbamazepine have been inconsistently effective. Strategies to prevent relapse by substituting medications that could later be discontinued more easily (i.e., antidepressants and azapirones) appear more useful but have been less well studied. Psychotherapeutic approaches appear to work, but specific therapeutic components are unclear and non-specific "placebo" effects may play an important role.

  18. Severe spontaneous vertebral fractures after denosumab discontinuation: three case reports. (United States)

    Aubry-Rozier, B; Gonzalez-Rodriguez, E; Stoll, D; Lamy, O


    Osteoporosis treatments are usually given for a limited period of time in order to balance benefits and risks. We report three cases of postmenopausal women without any previous fragility fracture who presented severe spontaneous vertebral fractures after denosumab discontinuation. We think that the occurrence of these fractures could be explained by the severe rebound effect observed after denosumab discontinuation and that a consensus regarding the end of treatment with denosumab has to be defined.

  19. Reasons for phosphate binder discontinuation vary by binder type. (United States)

    Wang, Steven; Anum, Emmanuel A; Ramakrishnan, Karthik; Alfieri, Thomas; Braunhofer, Peter; Newsome, Britt


    Nonadherence to phosphate binder regimen is common among end-stage renal disease patients and contributes to elevated phosphorus levels. Pill burden, side effects, complex regimens, and cost all contribute to nonadherence. We retrospectively analyzed reasons for discontinuation in hemodialysis patients receiving treatment at a large U.S. dialysis organization to better understand the drivers of nonadherence for particular phosphate binders. Patient electronic medical records were reviewed to identify phosphate binder prescriptions and reasons for discontinuation. Reasons for discontinuation were categorized and the percentage of patients on each type of phosphate binder was calculated within categories. Medicare patients of age ≥18 years, receiving in-center hemodialysis treatment between July 1, 2009, and June 30, 2011, were included in the analysis. We classified 30,933 patient records with a stated reason for phosphate binder discontinuation for this study. Of these records, 50.1% cited that the patient discontinued the phosphate binder but contained no additional information; "lab results" were cited for 27.4% of the reasons for discontinuation and "patient-reported side effects" for 10.8%. Although patients on lanthanum carbonate accounted for 14% of the total number reasons for discontinuation assessed, they comprised 40% of the "patient-reported side effects" category and were similarly overrepresented in 4 of the 5 subcategories. The high percentage of patient-reported side effects resulting in discontinuation identifies an unmet need for improved phosphate binders. A disproportionate percentage of patients prescribed lanthanum carbonate reported side effects, however further work is needed to identify the relative tolerability of phosphate binders and potential explanations. Copyright © 2014 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

  20. Search for seismic discontinuities in the lower mantle (United States)

    Vinnik, Lev; Kato, Mamoru; Kawakatsu, Hitoshi


    Indications of lower mantle discontinuities have been debated for decades, but still little is known about their properties, and their origins are enigmatic. In our study broad-band recordings of deep events are examined for the presence of signals from the lower-mantle discontinuities with a novel technique. We deconvolve vertical component of the P-wave coda in the period range around 10s by the S waveform and stack many deconvolved traces with moveout time corrections. In synthetic seismograms for an earth model without lower mantle discontinuities, the strongest signal thus detected in the time window of interest is often s`410'P phase (generated as S and reflected as P from the `410km' discontinuity above the source). In actual seismograms there are other phases that can be interpreted as converted from S to P at discontinuities in the lower mantle beneath the seismic source. We summarize the results of processing the seismograms (1) of deep events in Sunda arc at seismograph stations in east Asia, (2) deep Kermadec-Fiji-Tonga events at the J-array and FREESIA networks in Japan and stations in east Asia, and (3) deep events in the northwest Pacific region (Mariana, Izu-Bonin and the Japan arc) recorded at stations in north America. In our data there are indications of discontinuities near 860-880, 1010-1120, 1170-1250 and 1670-1800km depths. The clearest signals are obtained from the discontinuity at a depth of 1200km. We argue that the `900', `1200' and `1700km' discontinuities are global, but laterally variable in both depth and strength. Seismic stratification of the lower mantle may have bearings on the patterns of subduction, as revealed by tomographic models.

  1. A Nonparametric Bayesian Methodology for Regression Discontinuity Designs


    Branson, Zach; Rischard, Maxime; Bornn, Luke; Miratrix, Luke


    One of the most popular methodologies for estimating the average treatment effect at the threshold in a regression discontinuity design is local linear regression (LLR), which places larger weight on units closer to the threshold. We propose a Gaussian process regression method that acts as a Bayesian analog to LLR for sharp regression discontinuity designs. Our Gaussian process regression method provides a flexible fit for treatment and control responses by placing a general prior on the mea...

  2. Corporate Entrepreneurship in SMEs during the Search for Discontinuous Innovations

    DEFF Research Database (Denmark)

    van Geenhuizen, Maurits; Middel, Rick; Lassen, Astrid Heidemann


    The present paper illustrates, through three Danish/Dutch case studies, how several of the characteristics connected with SMEs entail significant reasons to make use of corporate entrepreneurship as a search strategy for discontinuous innovation. Characteristic dimensions of corporate entrepreneu......The present paper illustrates, through three Danish/Dutch case studies, how several of the characteristics connected with SMEs entail significant reasons to make use of corporate entrepreneurship as a search strategy for discontinuous innovation. Characteristic dimensions of corporate...

  3. Research progress on criteria for discontinuation of EGFR inhibitor therapy

    Directory of Open Access Journals (Sweden)

    Zhuang HQ


    Full Text Available Hong-qing Zhuang, Zhi-yong Yuan, Jun Wang, Ping Wang, Lu-jun Zhao, Bai-lin ZhangDepartment of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Lung Cancer Center, Tianjin, People's Republic of ChinaAbstract: The clinical success of the epidermal growth factor receptor (EGFR tyrosine kinase inhibitors (TKI as therapeutic agents has prompted great interest in their further development and clinical testing for a wide variety of malignancies. However, most studies have focused on the efficacy of TKI, and few studies have been done on the criteria for their discontinuation. The current standard for drug discontinuation is “until progression”, based on change in tumor size. However, tumor size is not related to the gene expression which determines the efficacy of TKI in the final analysis, and it is also difficult to make a thorough and correct prediction based on tumor size when the TKI is discontinued. Nevertheless, clinical evaluation of the criteria for TKI discontinuation is still in its early days. Some promising findings have started to emerge. With the improving knowledge of EGFR and its inhibitors, it is expected that the criteria for discontinuation of EGFR inhibitor therapy will become clearer.Keywords: epidermal growth factor receptor, drug discontinuation, acquired drug-resistance

  4. The risk of suicide after clozapine discontinuation: Cause for concern (United States)

    Patchan, Kathleen M.; Richardson, Charles; Vyas, Gopal; Kelly, Deanna L.


    BACKGROUND Clozapine is a second-generation antipsychotic that has been shown to reduce suicidal ideation and suicidal behaviors in patients with schizophrenia. However, it is underutilized because of its serious side effects. METHODS We describe 3 patients with a history of suicide ideation and attempts who were successfully treated and maintained in the community without suicidal tendencies while taking clozapine. All 3 patients, men in their 20s, discontinued clozapine because of side effects and subsequently committed suicide. We also review the literature on clozapine’s effects on suicidality. RESULTS In these 3 cases, suicide followed abrupt discontinuation of clozapine or transition to another antipsychotic. CONCLUSIONS This case series is the first of its kind to document the risk of suicide when clozapine is discontinued. The decision to discontinue clozapine should be made carefully, especially because clozapine is considered the treatment of last resort for patients with treatment-resistant schizophrenia and suicidal ideation. We stress the importance of minimizing the risk of abrupt clozapine discontinuation and recommend further evaluation of suicide ideation and attempts when clozapine is discontinued. PMID:26554366

  5. A Discontinuous Galerkin Chimera Overset Solver (United States)

    Galbraith, Marshall Christopher

    This work summarizes the development of an accurate, efficient, and flexible Computational Fluid Dynamics computer code that is an improvement relative to the state of the art. The improved accuracy and efficiency is obtained by using a high-order discontinuous Galerkin (DG) discretization scheme. In order to maximize the computational efficiency, quadrature-free integration and numerical integration optimized as matrix-vector multiplications is employed and implemented through a pre-processor (PyDG). Using the PyDG pre-processor, a C++ polynomial library has been developed that uses overloaded operators to design an efficient Domain Specific Language (DSL) that allows expressions involving polynomials to be written as if they are scalars. The DSL, which makes the syntax of computer code legible and intuitive, promotes maintainability of the software and simplifies the development of additional capabilities. The flexibility of the code is achieved by combining the DG scheme with the Chimera overset method. The Chimera overset method produces solutions on a set of overlapping grids that communicate through an exchange of data on grid boundaries (known as artificial boundaries). Finite volume and finite difference discretizations use fringe points, which are layers of points on the artificial boundaries, to maintain the interior stencil on artificial boundaries. The fringe points receive solution values interpolated from overset grids. Proper interpolation requires fringe points to be contained in overset grids. Insufficient overlap must be corrected by modifying the grid system. The Chimera scheme can also exclude regions of grids that lie outside the computational domain; a process commonly known as hole cutting. The Chimera overset method has traditionally enabled the use of high-order finite difference and finite volume approaches such as WENO and compact differencing schemes, which require structured meshes, for modeling fluid flow associated with complex

  6. Wildfire and landscape change (United States)

    Santi, P.; Cannon, S.; DeGraff, J.


    Wildfire is a worldwide phenomenon that is expected to increase in extent and severity in the future, due to fuel accumulations, shifting land management practices, and climate change. It immediately affects the landscape by removing vegetation, depositing ash, influencing water-repellent soil formation, and physically weathering boulders and bedrock. These changes typically lead to increased erosion through sheetwash, rilling, dry ravel, and increased mass movement in the form of floods, debris flow, rockfall, and landslides. These process changes bring about landform changes as hillslopes are lowered and stream channels aggrade or incise at increased rates. Furthermore, development of alluvial fans, debris fans, and talus cones are enhanced. The window of disturbance to the landscape caused by wildfire is typically on the order of three to four years, with some effects persisting up to 30 years.

  7. Conceiving Landscape through Film

    DEFF Research Database (Denmark)

    Farsø, Mads; Munck Petersen, Rikke


    This article shows how the media of film can be integrated, explored and can add value to architectural design studios and practice. It elucidates how film may offer an alternative position in architecture, where landscapes and cities are thought, planned and developed in closer relation...... to their spatial and sensory effects on humans. It underscores that the film camera can work as a kind of amplifier of how we, with our bodies, perceive space and project space. In the “Landscape Film” Studio at University of Copenhagen the film medium was tested as a combined registration and design tool...... for a new Nature Park south of Copenhagen. The final studio films and designs show how resonate recordings of sound, time and a bodily presence may simulate an Einfühling that inspires an alternative architecture of relations: the ambient, the changeable and the volatile. They also emphasize that an ability...

  8. Driving the Landscape (United States)

    Haff, P. K.


    Technological modification of the earth's surface (e.g., agriculture, urbanization) is an old story in human history, but what about the future? The future of landscape in an accelerating technological world, beyond a relatively short time horizon, lies hidden behind an impenetrable veil of complexity. Sufficiently complex dynamics generates not only the trajectory of a variable of interest (e.g., vegetation cover) but also the environment in which that variable evolves (e.g., background climate). There is no way to anticipate what variables will define that environment—the dynamics creates its own variables. We are always open to surprise by a change of conditions we thought or assumed were fixed or by the appearance of new phenomena of whose possible existence we had been unaware or thought unlikely. This is especially true under the influence of technology, where novelty is the rule. Lack of direct long-term predictability of landscape change does not, however, mean we cannot say anything about its future. The presence of persistence (finite time scales) in a system means that prediction by a calibrated numerical model should be good for a limited period of time barring bad luck or faulty implementation. Short-term prediction, despite its limitations, provides an option for dealing with the longer-term future. If a computer-controlled car tries to drive itself from New York to Los Angeles, no conceivable (or possible) stand-alone software can be constructed to predict a priori the space-time trajectory of the vehicle. Yet the drive is normally completed easily by most drivers. The trip is successfully completed because each in a series of very short (linear) steps can be "corrected" on the fly by the driver, who takes her cues from the environment to keep the car on the road and headed toward its destination. This metaphor differs in a fundamental way from the usual notion of predicting geomorphic change, because it involves a goal—to reach a desired

  9. Data anonymization patent landscape


    Mirjana Pejić Bach; Jasmina Pivar; Ksenija Dumičić


    The omnipresent, unstoppable increase in digital data has led to a greater understanding of the importance of data privacy. Different approaches are used to implement data privacy. The goal of this paper is to develop a data anonymization patent landscape, by determining the following: (i) the trend in data anonymization patenting, (ii) the type of technical content protected in data anonymization, (iii) the organizations and countries most active in patenting data anonymization know-how; and...

  10. Patent Landscape for Nanotechnology


    Alexey Streletskiy; Vladimir Zabavnikov; Emil Aslanov; Dmitriy Kotlov


    This paper investigates the methodological aspects of nanotechnology patent landscaping. The authors suggest that nanotechnologies take precedence over other technological trends, an assertion that is confirmed by current assessments and forecasts regarding the size of the nanotechnology product market. In this paper the authors analyse patent activity within the Russian Federation and globally by building a patent map of nanotechnology and the associated field of metallurgy. Using this as a ...

  11. Landscape evolution of Antarctica (United States)

    Jamieson, S.S.R.; Sugden, D.E.


    The relative roles of fluvial versus glacial processes in shaping the landscape of Antarctica have been debated since the expeditions of Robert Scott and Ernest Shackleton in the early years of the 20th century. Here we build a synthesis of Antarctic landscape evolution based on the geomorphology of passive continental margins and former northern mid-latitude Pleistocene ice sheets. What makes Antarctica so interesting is that the terrestrial landscape retains elements of a record of change that extends back to the Oligocene. Thus there is the potential to link conditions on land with those in the oceans and atmosphere as the world switched from a greenhouse to a glacial world and the Antarctic ice sheet evolved to its present state. In common with other continental fragments of Gondwana there is a fluvial signature to the landscape in the form of the coastal erosion surfaces and escarpments, incised river valleys, and a continent-wide network of river basins. A selective superimposed glacial signature reflects the presence or absence of ice at the pressure melting point. Earliest continental-scale ice sheets formed around 34 Ma, growing from local ice caps centered on mountain massifs, and featured phases of ice-sheet expansion and contraction. These ice masses were most likely cold-based over uplands and warm-based across lowlands and near their margins. For 20 million years ice sheets fluctuated on Croll-Milankovitch frequencies. At ~14 Ma the ice sheet expanded to its maximum and deepened a preexisting radial array of troughs selectively through the coastal mountains and eroded the continental

  12. Survival after dialysis discontinuation and hospice enrollment for ESRD. (United States)

    O'Connor, Nina R; Dougherty, Meredith; Harris, Pamela S; Casarett, David J


    Textbooks report that patients with ESRD survive for 7-10 days after discontinuation of dialysis. Studies describing actual survival are limited, however, and research has not defined patient characteristics that may be associated with longer or shorter survival times. The goals of this study were to determine the mean life expectancy of patients admitted to hospice after discontinuation of dialysis, and to identify independent predictors of survival time. Data for demographics, clinical characteristics, and survival were obtained from 10 hospices for patients with ESRD who discontinued dialysis before hospice admission. Data were collected for patients admitted between January 1, 2008 and May 15, 2012. All hospices were members of the Coalition of Hospices Organized to Investigate Comparative Effectiveness network, which obtains de-identified data from an electronic medical record. Of 1947 patients who discontinued dialysis, the mean survival after hospice enrollment was 7.4 days (range, 0-40 days). Patients who discontinued dialysis had significantly shorter survival compared with other patients (n=124,673) with nonrenal hospice diagnoses (mean survival 54.4 days; hazard ratio, 2.96; 95% confidence interval, 2.82 to 3.09; P<0.001). A Cox proportional hazards model identified seven independent predictors of earlier mortality after dialysis discontinuation, including male sex, referral from a hospital, lower functional status (Palliative Performance Scale score), and the presence of peripheral edema. Patients who discontinue dialysis have significantly shorter survival than other hospice patients. Individual survival time varies greatly, but several variables can be used to predict survival and tailor a patient's care plan based on estimated prognosis.

  13. Discontinuous insurance coverage predicts prolonged hospital stay after pediatric adenotonsillectomy. (United States)

    Tumin, Dmitry; King, Adele; Walia, Hina; Tobias, Joseph D; Raman, Vidya T


    Changes in health insurance coverage have been implicated in limiting access to care and increasing morbidity risk. The consequences of insurance discontinuity for surgical outcomes are unclear. In this study, we explored whether recent insurance discontinuity was associated with prolonged inpatient hospitalization after adenotonsillectomy in children. We retrospectively evaluated single-center data on children aged 2-18 y undergoing adenotonsillectomy with overnight stay in 2009-2014. Insurance coverage at surgery and over the preceding year was categorized as (1) continuous private, (2) continuous Medicaid, or (3) discontinuous (changes or gaps in coverage). The association between insurance discontinuity and prolonged hospitalization (≥2 d) was evaluated using multivariable logistic regression. The study included 1013 girls and 983 boys (aged 4.5 ± 2.9 y), of whom 205 (10%) required prolonged hospitalization. Insurance was continuous private for 749 patients (38%), continuous Medicaid for 1121 patients (56%), and discontinuous for 126 patients (6%). Prolonged stay was most common with discontinuous insurance (23/126, 18%), followed by continuous Medicaid (117/1,121, 10%), and continuous private insurance (65/749, 9%; P = 0.004). In multivariable analysis, discontinuous insurance remained associated with prolonged hospital stay, compared with continuous private insurance (odds ratio = 1.88; 95% confidence interval: 1.06-3.33; P = 0.031), and compared with continuous Medicaid (odds ratio = 1.86; 95% confidence interval: 1.09-3.19; P = 0.023). This study demonstrates greater odds of prolonged hospitalization after adenotonsillectomy among children with recent gaps or changes in insurance coverage and illustrates the feasibility of studying influences of health insurance change on surgical outcomes using existing data in hospital electronic records. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Identification Of Minangkabau Landscape Characters (United States)

    Asrina, M.; Gunawan, A.; Aris, Munandar


    Minangkabau is one of cultures in indonesia which occupies landscape intact. Landscape of Minangkabau have a very close relationship with the culture of the people. Uniqueness of Minangkabau culture and landscape forming an inseparable characterunity. The landscape is necessarily identified to know the inherent landscape characters. The objective of this study was to identify the character of the Minangkabau landscape characterizes its uniqueness. The study was conducted by using descriptive method comprised literature review and field observasion. Observed the landscape characters comprised two main features, they were major and minor features. Indetification of the features was conducted in two original areas (darek) of the Minangkabau traditional society. The research results showed that major features or natural features of the landscape were predominantly landform, landcover, and hidrology. All luhak (districts) of Minangkabau showed similar main features such as hill, canyon, lake, valley, and forest. The existence of natural features such as hills, canyon and valleys characterizes the nature of minangkabau landscape. Minor features formed by Minangkabau cultural society were agricultural land and settlement. Rumah gadang (big house) is one of famous minor features characterizes the Minangkabau culture. In addition, several historical artefacts of building and others structure may strengthen uniqueness of the Minangkabau landscape character, such as The royal palace, inscription, and tunnels.

  15. Incorporating Bioenergy in Sustainable Landscape Designs Workshop Two: Agricultural Landscapes

    Energy Technology Data Exchange (ETDEWEB)



    The Bioenergy Technologies Office hosted two workshops on Incorporating Bioenergy in Sustainable Landscape Designs with Oak Ridge and Argonne National Laboratories in 2014. The second workshop focused on agricultural landscapes and took place in Argonne, IL from June 24—26, 2014. The workshop brought together experts to discuss how landscape design can contribute to the deployment and assessment of sustainable bioenergy. This report summarizes the discussions that occurred at this particular workshop.

  16. Hospital Factors Associated With Care Discontinuity Following Emergency General Surgery. (United States)

    Havens, Joaquim M; Olufajo, Olubode A; Tsai, Thomas C; Jiang, Wei; Columbus, Alexandra B; Nitzschke, Stephanie L; Cooper, Zara; Salim, Ali


    Although there is evidence that changes in clinicians during the continuum of care (care discontinuity) are associated with higher mortality and complications among surgical patients, little is known regarding the drivers of care discontinuity among emergency general surgery (EGS) patients. To identify hospital factors associated with care discontinuity among EGS patients. We performed a retrospective analysis of the 100% Medicare inpatient claims file, from January 1, 2008, to November 30, 2011, and matched patient details to hospital information in the 2011 American Hospital Association Annual Survey database. We selected patients aged 65 years and older who had the most common procedures associated with the previously defined American Association for the Surgery of Trauma EGS diagnosis categories and survived to hospital discharge across the United States. The current analysis was conducted from February 1, 2016, to March 24, 2016. Care discontinuity defined as readmission within 30 days to nonindex hospitals. There were 109 443 EGS patients readmitted within 30 days of discharge and 20 396 (18.6%) were readmitted to nonindex hospitals. Of the readmitted patients, 61 340 (56%) were female. Care discontinuity was higher among patients who were male (19.5% vs 18.0%), those younger than 85 years old (19.0% vs 16.6%), and those who lived 12.8 km (8 miles) or more away from the index hospitals (23.7% vs 14.8%) (all P < .001). Care discontinuity was independently associated with mortality (adjusted odds ratio [aOR], 1.16; 95% CI, 1.08-1.25). Hospital factors associated with care discontinuity included bed size of 200 or more (aOR, 1.45; 95% CI, 1.36-1.54), safety-net status (aOR, 1.35; 95% CI, 1.27-1.43), and teaching status (aOR, 1.18; 95% CI, 1.09-1.28). Care discontinuity was significantly lower among designated trauma centers (aOR, 0.89; 95% CI, 0.83-0.94) and highest among hospitals in the Midwest (aOR, 1.15; 95% CI, 1.05-1.26). Nearly 1 in 5 older EGS

  17. The effect of mechanical discontinuities on the growth of faults (United States)

    Bonini, Lorenzo; Basili, Roberto; Bonanno, Emanuele; Toscani, Giovanni; Burrato, Pierfrancesco; Seno, Silvio; Valensise, Gianluca


    The growth of natural faults is controlled by several factors, including the nature of host rocks, the strain rate, the temperature, and the presence of fluids. In this work we focus on the mechanical characteristics of host rocks, and in particular on the role played by thin mechanical discontinuities on the upward propagation of faults and on associated secondary effects such as folding and fracturing. Our approach uses scaled, analogue models where natural rocks are simulated by wet clay (kaolin). A clay cake is placed above two rigid blocks in a hanging wall/footwall configuration on either side of a planar fault. Fault activity is simulated by motor-controlled movements of the hanging wall. We reproduce three types of faults: a 45°-dipping normal fault, a 45°-dipping reverse fault and a 30°-dipping reverse fault. These angles are selected as representative of most natural dip-slip faults. The analogues of the mechanical discontinuities are obtained by precutting the wet clay cake before starting the hanging wall movement. We monitor the experiments with high-resolution cameras and then obtain most of the data through the Digital Image Correlation method (D.I.C.). This technique accurately tracks the trajectories of the particles of the analogue material during the deformation process: this allows us to extract displacement field vectors plus the strain and shear rate distributions on the lateral side of the clay block, where the growth of new faults is best seen. Initially we run a series of isotropic experiments, i.e. experiments without discontinuities, to generate a reference model: then we introduce the discontinuities. For the extensional models they are cut at different dip angles, from horizontal to 45°-dipping, both synthetic and antithetic with respect to the master fault, whereas only horizontal discontinuities are introduced in the contractional models. Our experiments show that such discontinuities control: 1) the propagation rate of faults

  18. Understanding patchy landscape dynamics: towards a landscape language.

    Directory of Open Access Journals (Sweden)

    Cédric Gaucherel

    Full Text Available Patchy landscapes driven by human decisions and/or natural forces are still a challenge to be understood and modelled. No attempt has been made up to now to describe them by a coherent framework and to formalize landscape changing rules. Overcoming this lacuna was our first objective here, and this was largely based on the notion of Rewriting Systems, also called Formal Grammars. We used complicated scenarios of agricultural dynamics to model landscapes and to write their corresponding driving rule equations. Our second objective was to illustrate the relevance of this landscape language concept for landscape modelling through various grassland managements, with the final aim to assess their respective impacts on biological conservation. For this purpose, we made the assumptions that a higher grassland appearance frequency and higher land cover connectivity are favourable to species conservation. Ecological results revealed that dairy and beef livestock production systems are more favourable to wild species than is hog farming, although in different ways. Methodological results allowed us to efficiently model and formalize these landscape dynamics. This study demonstrates the applicability of the Rewriting System framework to the modelling of agricultural landscapes and, hopefully, to other patchy landscapes. The newly defined grammar is able to explain changes that are neither necessarily local nor Markovian, and opens a way to analytical modelling of landscape dynamics.

  19. The role of landscape planning in European landscape convention implementation

    Directory of Open Access Journals (Sweden)

    Vasiljević Nevena


    Full Text Available The most important recent policy initiative concerning quality and diversity, as well as natural and cultural landscape's values within all Europe is European Landscape Convention. The Convention was adopted by Council of Europe's Community of Ministers on 20th October 2000., in Firenze, Italy. The main goal of the Convention is protection, planning and management of the landscape as important part of the quality of life for people living everywhere: in urban areas and in countryside, in degraded areas as well as in the areas with high quality and those recognized as being of outstanding beauty. Serbia has singed Convention on 21 of September 2007. Diversity and quality, the cultural and natural values linked to European landscapes are part of Europe's common heritage, and it is important to co-operate towards its protection, management and planning According to explored international experiences, landscape plan, with its known methodology, is recognized as the most suitable tool in the most Countries which have already implemented European Landscape Convention. As to situation in Serbia, landscape planning is not treated in adequate or appropriate way within system of spatial planning. On the basis of the recent European experiences regarding The European Landscape Convention, the paper will underline the inevitability of landscape planning integration into the spatial planning system at the national, regional and city level, in Serbia.

  20. Model for vortex turbulence with discontinuities in the solar wind

    Directory of Open Access Journals (Sweden)

    O. P. Verkhoglyadova


    Full Text Available A model of vortex with embedded discontinuities in plasma flow is developed in the framework of ideal MHD in a low b plasma. Vortex structures are considered as a result of 2-D evolution of nonlinear shear Alfvén waves in the heliosphere. Physical properties of the solutions and vector fields are analyzed and the observational aspects of the model are discussed. The ratio of normal components to the discontinuity Br /Vr can be close to -2. The alignment between velocity and magnetic field vectors takes place. Spacecraft crossing such vortices will typically observe a pair of discontinuities, but with dissimilar properties. Occurrence rate for different discontinuity types is estimated and agrees with observations in high-speed solar wind stream. Discontinuity crossing provides a backward rotation of magnetic field vector and can be observed as part of a backward arc. The Ulysses magnetometer data obtained in the fast solar wind are compared with the results of theoretical modelling.

  1. An analysis of B-cell epitope discontinuity. (United States)

    Sivalingam, Ganesh N; Shepherd, Adrian J


    Although it is widely acknowledged that most B-cell epitopes are discontinuous, the degree of discontinuity is poorly understood. For example, given that an antigen having a single epitope that has been chopped into peptides of a specific length, what is the likelihood that one of the peptides will span all the residues belonging to that epitope? Or, alternatively, what is the largest proportion of the epitope's residues that any peptide is likely to contain? These and similar questions are of direct relevance both to computational methods that aim to predict the location of epitopes from sequence (linear B-cell epitope prediction methods) and window-based experimental methods that aim to locate epitopes by assessing the strength of antibody binding to synthetic peptides on a chip. In this paper we present an analysis of the degree of B-cell epitope discontinuity, both in terms of the structural epitopes defined by a set of antigen-antibody complexes in the Protein Data Bank, and with respect to the distribution of key residues that form functional epitopes. We show that, taking a strict definition of discontinuity, all the epitopes in our data set are discontinuous. More significantly, we provide explicit guidance about the choice of peptide length when using window-based B-cell epitope prediction and mapping techniques based on a detailed analysis of the likely effectiveness of different lengths. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. The impact of contemporary contact lenses on contact lens discontinuation. (United States)

    Dumbleton, Kathy; Woods, Craig A; Jones, Lyndon W; Fonn, Desmond


    Discontinuation or "dropout" from contact lens (CL) wear continues to afflict the CL industry. This study was conducted to determine whether the advent of new CL materials and designs has impacted the dropout rate and the reasons for discontinuation. Current and lapsed CL wearers residing in Canada were recruited using Facebook to take part in an on line survey investigating CL wearing experiences during 2008 to 2010 and to establish the percentage of participants who temporarily and permanently discontinued CL wear during the period surveyed. Four thousand two hundred seven eligible surveys were received (64% female; median age 27 years). Forty percent had lapsed from lens wear for at least 4 months; however, 62% of the lapsed wearers (LWs) resumed wear. There were no differences between LWs and nonlapsed wearers (NLWs) with respect to gender; however, LWs were older, started lens wear when older, and had not worn lenses for as long as NLWs (all Plenses and hydrogel CLs (24% vs. 19% and 22% vs. 18%, respectively, P≤0.001). Primary reasons for discontinuation were discomfort (24%), dryness (20%), red eyes (7%), and expense (7%). Compliance with lens replacement was no different between LWs and NLWs (48% vs. 45%). About 23% of those surveyed had discontinued CL wear permanently. The primary reasons for dropping out continue to be discomfort and dryness. Dropout rates were lower in silicone hydrogel wearers.

  3. Integrated landscape initiatives in Europe

    DEFF Research Database (Denmark)

    García-Martín, María; Bieling, Claudia; Hart, Abigail


    Landscapes are linked to human well-being in a multitude of ways, some of which are challenged by global market forces and traditional management approaches. In response to this situation there has been a rise in local initiatives to sustain the values of landscape. The aim of this paper...... is to provide a systematic analysis of the spectrum of these initiatives in Europe in terms of patterns of organisation, participants, resources, problems, and landscape values addressed. This review collects examples of integrated landscape initiatives from all over Europe through systematic internet key word...... searches and canvassing of European umbrella organisations; followed by an online survey of representatives from the identified initiatives (n??=??71). Our results show that the most relevant characteristics of integrated landscape initiatives in Europe are: a holistic approach to landscape management...

  4. Landscape Architecture in Contemporary Danish Suburban Development

    DEFF Research Database (Denmark)

    Roden, Tina Maria


    it became a theory, landscape urbanism has been common practice in European design projects. This implies that the urban challenges have been in the centre of landscape thought and practice for so long that Danish landscape architecture already includes urbanism. In order to recover momentum in Danish urban...... design, it is argued that the current discourse of landscape urbanism needs to define itself more clearly in relation to the Danish landscape architecture tradition and more actively consider amenity and aesthetics. Via the discourse of landscape urbanism, landscape architecture in Danish suburban...... the indeterminacy of the future. KEYWORDS: Suburban development, landscape urbanism, landscape architecture, sustainability...

  5. GIS-based landscape design research : Stourhead landscape garden as a case study

    NARCIS (Netherlands)

    Nijhuis, S.


    Landscape design research is important for cultivating spatial intelligence in landscape architecture. This study explores GIS (geographic information systems) as a tool for landscape design research – investigating landscape designs to understand them as architectonic compositions and to acquire

  6. Analysis of HTTR Core with Different Hexagonal Discontinuity Factors

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Chang Joon; Lee, Hyun Chul; Jo, Chang Keun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)


    In the nodal diffusion calculation, few group equivalent constants are generated by multi-group neutron transport theory. Especially, in the nodal calculation, not only a homogenized group constants but discontinuity factors are needed. In this study, whole core transport calculation is performed by DeCART code to generate equivalent group constant and assembly discontinuity factor (ADF). Then the nodal diffusion calculations are carried out by CAPP code with the generated parameters and ADF. In this study, the calculations are applied to the High Temperature Engineering Test Reactor (HTTR) core. The diffusion nodal calculations with different ADF option have been applied to the HTTR 2-D core analysis. From the calculation results, the discontinuity factor calculation option 1 shows small difference in k-effective. Also, the difference in the relative power distribution is small with case 1 option.

  7. Actor Bonds in Situations of Discontinuous Business Activities

    DEFF Research Database (Denmark)

    Skaates, Maria Anne


    . Furthermore the governance structure of markets characterized by discontinuous business activities is either that of the "socially constructed market" (Skaates, 2000) or that of the (socially constructed) network (Håkansson and Johanson, 1993). Additionally relationships and actor bonds vary substantially...... in situations of discontinuity. Therefore an analysis and comparison of relevant concepts that capture the key generative features of actor bonds in both socially constructed networks and socially constructed markets is undertaken. These concepts include the "milieu" of project marketing (Cova et al., 1996......) and the institutional concept of the "field". Finally this paper introduces the concept of "social capital" (Bourdieu, 1983) and discusses whether it can be used to conceptualize the dynamic features of actor bonds in situations of discontinuity....

  8. Occupy the Financial Niche – Saturation and Crisis (discontinuous decisions

    Directory of Open Access Journals (Sweden)

    Ionut PURICA


    Full Text Available The model presented is proposing an approach that could verify the nonlinear behaviour during a crisis, such that to quantify and predict potential discontinuous behaviour. In this case, the crisis behaviour associated with financial funds reallocation among various credit instruments, described as memes with the sense of Dawkins, is shown to be of discontinuous nature stemming from a logistic penetration in the financial behaviour niche. Actually the logistic penetration is typical in creating cyclic behaviour of economic structures as shown by Marchetti and others from IIASA. A Fokker-Planck equation description results in a stationary solution having a bifurcation like solution with evolution trajectories on a ‘cusp’ type catastrophe that may describe discontinuous decision behaviour

  9. Soil conservation service landscape resource management (United States)

    Sally Schauman; Carolyn Adams


    SCS Landscape Resource Management (LRM) is the application of landscape architecture to SCS conservation activities. LRM includes but is not limited to visual resource management. LRM can be summarized in three principles: (1) SCS landscape architecture considers the landscape as a composite of ecological, social and visual resources; (2) SCS landscapes exist in the...

  10. Energy landscape Allgaeu; Energielandschaft Allgaeu

    Energy Technology Data Exchange (ETDEWEB)



    In tandems with questions on the energy policy turnaround, the topics cultural landscape history, morphology, actual land use, tourism, settlement development or infrastructure are summarized in regional concepts and designs to a consistent landscape. Thus, a true integration of renewable energies in the landscape enhances existing or creates completely new landscape qualities. Energy supply shall be understood as a component of the every day life world. The energy supply shall not be hidden any more, but it rather should be communicated as the brand 'Allgaeu'.

  11. Marc Treib: Representing Landscape Architecture

    DEFF Research Database (Denmark)

    Braae, Ellen Marie


    The editor of Representing Landscape Architecture, Marc Treib, argues that there is good reason to evaluate the standard practices of representation that landscape architects have been using for so long. In the rush to the promised land of computer design these practices are now in danger of being...... left by the wayside. The 14 often both fitting and well crafted contributions of this publication offer an approach to how landscape architecture has been and is currently represented; in the design study, in presentation, in criticism, and in the creation of landscape architecture....

  12. Activation of diffuse discontinuities and folding of sedimentary layers (United States)

    Guiton, Martin L. E.; Leroy, Yves M.; Sassi, William


    Folding of sedimentary layers is often accommodated by the opening or sliding of inherited and new discontinuities which are assumed here to be diffuse so that a continuum description applies at the fold scale. The rock rheology is then described with an elastoplasticity model for which the permanent deformation is of simple shear (sliding) or dilation (opening) with respect to specific orientations of the new or inherited diffuse discontinuities. To illustrate the relation between folding and activation of diffuse discontinuities, a three-dimensional layer under compression in the two horizontal directions and sustaining the overburden lithostatic pressure is studied. Cylindrical buckling occurs either before (elastic) or after the diffuse discontinuities have been activated. If buckling is elastic, inherited vertical discontinuities, striking obliquely to the fold geometrical axes, are activated in a sliding mode in the outer arc, leading to a rotation of the principal stress directions. Opening is then detected across new vertical planes striking obliquely to the fold axis. The activation of inherited or new vertical discontinuities can be suppressed if sliding takes place along weak bedding interfaces. Alternatively, early and homogeneous layer-parallel shortening, marked by a reverse fault mode, drastically reduces the critical buckling load compared to the Euler load and modifies the final geometry of buckling which is then more of a circular dome shape. The switching in buckling mode results in the fold limbs in a change from the early reverse fault to a strike-slip fault sliding and to opening across diffuse planes oriented consistently with the final circular structure.

  13. A Broad Depressed 410-km Discontinuity beneath Northeast Asia (United States)

    Li, J.; Guo, G.; WANG, X.


    The topography of the upper mantle discontinuities is important for good understanding of the thermal structure, composition of the mantle, and scales of mantle circulation as well. We applied both receiver function analysis and multiple-ScS reverberations to seismic waveforms recorded by stations beneath land and ocean, respectively. We obtained a complete image of the upper mantle discontinuities beneath northeast Asia, covering from the Okhotsk Sea, far east Russia, Japan Sea and northeast China. Results with different resolutions from different methods are compared in detail, and the comparison shows that long-period ScS reverberation signals is effective in extracting the robust features of the upper mantle discontinuities. Through the integrated depth undulation map covering both sea and land, we detected an obvious depression of the 410-km discontinuity with value 8-25 km, anticorrelated with a wide range of depressed 660-km discontinuity. The depression of the 660 can be explained by the temperature anomaly associated to the subducting Pacific slab. The landward extension of the depressed 410, however, is of large scale with a lateral range of at least 800-1000 km. Mechanism invoking chemical heterogeneity in the mantle transition zone was explored to explain the observation. We speculate that the broadly depressed 410 beneath west Japan Sea, part of Okhotsk Sea, and northeast China might be caused by high water content at the top of the mantle transition zone. The significant trench rollback motion of the subducting Pacific slab from the Miocene might explain the widespread distribution of the depression of the 410. The west edge of observed depressed 410-km discontinuity might pin the initial location where the Pacific subducting slab had been furthest before the occurrence of trench retreating.

  14. Associations Between Patient and Anthropometric Characteristics and Aromatase Inhibitor Discontinuation. (United States)

    Henry, N Lynn; Speth, Kelly; Lintermans, Anneleen; Kidwell, Kelley M; Carlson, Rachel; Hayes, Daniel F; Neven, Patrick


    Toxicity can lead to noncontinuation of adjuvant endocrine therapy. We hypothesized that endocrine therapy-induced changes in grip strength would predict for early discontinuation of therapy because of musculoskeletal toxicity and would be associated with a patient's body mass index. Postmenopausal women with breast cancer starting a new adjuvant endocrine therapy were enrolled in the present study. The patients were monitored for 12 months to assess their symptoms, endocrine therapy adherence and change in grip strength and baseline body mass index. The association between the change in grip strength and interval to discontinuation was assessed using a joint longitudinal and survival model. Of the 93 aromatase inhibitor (AI)-treated and 22 tamoxifen-treated patients, 40.9% and 9% discontinued endocrine therapy within 12 months because of toxicity, respectively (P = .019). A trend was seen toward a greater decrease in grip strength in the AI-treated patients over time (P = .055); however, the decrease was not significantly associated with the interval to discontinuation (P = .96). Receipt of an AI (hazard ratio, 5.49; P = .019) and baseline pain (hazard ratio, 1.19; P = .004) significantly decreased the interval to discontinuation. In contrast with the findings from previous reports, the change in grip strength in our study was not associated with the interval to discontinuation of AI therapy. Future research should focus on proactive treatment of patients at increased risk of AI intolerance, such as those with high levels of pre-existing pain. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Stonehenge and its Landscape (United States)

    Ruggles, Clive L. N.

    In the 1960s and 1970s, Stonehenge polarized academic opinion between those (mainly astronomers) who claimed it demonstrated great astronomical sophistication and those (mainly archaeologists) who denied it had anything to do with astronomy apart from the solstitial alignment of its main axis. Now, several decades later, links to the annual passage of the sun are generally recognized as an essential part of the function and meaning not only of Stonehenge but also of several other nearby monuments, giving us important insights into beliefs and actions relating to the seasonal cycle by the prehistoric communities who populated this chalkland landscape in the third millennium BC Links to the moon remain more debatable.

  16. Becoming an English language teacher: Continuities and Discontinuities

    Directory of Open Access Journals (Sweden)

    Werbińska Dorota


    Full Text Available The aim of the paper is to report a three-year phenomenographic study conducted on seven EFL Polish teachers with the focus on presenting how they experience different aspects of language teaching at three crucial stages: 1 the time of ELT theory studying, 2 the time of school placement, 3 the time of first-year working as professional teachers. Each stage of the study is presented from the perspective of affordances standing for the respondents’ expectations (continuities as well as constraints (discontinuities. The article concludes that discontinuities, rather than continuities, can prove invaluable in language teacher identity development.

  17. Strong discontinuity with cam clay under large deformations

    DEFF Research Database (Denmark)

    Katic, Natasa; Hededal, Ole


    The work shows simultaneous implementation of Strong discontinuity approach (SDA) by means of Enhanced Assumed Strain (EAS) and Critical State Soil Mechanics CSSM) in large strain regime. The numerical model is based on an additive decomposition of the displacement gradient into a conforming and ...... and an enhanced part. The localized deformations are approximated by means of a discontinuous displacement field. The applied algorithm leads to a predictor/corrector procedure which is formally identical to the returnmapping algorithm of classical (local and continuous) Cam clay model....

  18. Straight to the point: how people encode linear discontinuations

    Directory of Open Access Journals (Sweden)

    Rodrigo I. Mora


    Full Text Available Spatial discontinuations, as those found in cities and buildings, are everyday events. But, how do we encode and classify such misalignments? This is the topic of this paper. Twenty participants were asked to classify a total of 51 icons showing an upward-moving line being misaligned to the right, left and straight down. The results show that subjects were very sensitive to slight discontinuations occurring to vertical lines and that there was not exact symmetry between the left and right axis, meaning that the pieces slightly misaligned to the left were encoded differently than those misaligned to the right

  19. Discontinuous Sturm-Liouville Problems and Associated Sampling Theories

    Directory of Open Access Journals (Sweden)

    M. M. Tharwat


    Full Text Available This paper investigates the sampling analysis associated with discontinuous Sturm-Liouville problems with eigenvalue parameters in two boundary conditions and with transmission conditions at the point of discontinuity. We closely follow the analysis derived by Fulton (1977 to establish the needed relations for the derivations of the sampling theorems including the construction of Green's function as well as the eigenfunction expansion theorem. We derive sampling representations for transforms whose kernels are either solutions or Green's functions. In the special case, when our problem is continuous, the obtained results coincide with the corresponding results in the work of Annaby and Tharwat (2006.

  20. Malignant hyperthermia resolving with discontinuation of sevoflurane alone

    Directory of Open Access Journals (Sweden)

    Abdullah Abolkhair


    Full Text Available An otherwise healthy 13 year old developed hypercarbia and increased temperature during anesthesia with sevoflurane. Discontinuation of sevoflurane, surface cooling, and hyperventilation resulted in prompt resolution. However, hyperkalemia continued to raise the suspicion for malignant hyperthermia, which was ultimately confirmed by ryanodine receptor gene sequencing. The case underlines the importance of intraoperative monitoring of end-tidal CO2 and temperature and the potential benefits of early discontinuation of inhalational anesthetics in the presence of signs and symptoms suspicious for malignant hyperthermia. The severe hyperkalemia suggests that standard guidelines for diagnosis and treatment of malignant hyperthermia, including dantrolene treatment, should be followed whenever malignant hyperthermia is suspected.

  1. Discontinuous Galerkin finite element methods for gradient plasticity.

    Energy Technology Data Exchange (ETDEWEB)

    Garikipati, Krishna. (University of Michigan, Ann Arbor, MI); Ostien, Jakob T.


    In this report we apply discontinuous Galerkin finite element methods to the equations of an incompatibility based formulation of gradient plasticity. The presentation is motivated with a brief overview of the description of dislocations within a crystal lattice. A tensor representing a measure of the incompatibility with the lattice is used in the formulation of a gradient plasticity model. This model is cast in a variational formulation, and discontinuous Galerkin machinery is employed to implement the formulation into a finite element code. Finally numerical examples of the model are shown.


    Directory of Open Access Journals (Sweden)

    P. V. Bulat


    Full Text Available We consider numerical simulation of shock wave refraction on plane contact discontinuity, separating two gases with different density. Discretization of Euler equations is based on finite volume method and WENO finite difference schemes, implemented on unstructured meshes. Integration over time is performed with the use of the third-order Runge–Kutta stepping procedure. The procedure of identification and classification of gas dynamic discontinuities based on conditions of dynamic consistency and image processing methods is applied to visualize and interpret the results of numerical calculations. The flow structure and its quantitative characteristics are defined. The results of numerical and experimental visualization (shadowgraphs, schlieren images, and interferograms are compared.

  3. An Online Landscape Object Library to Support Interactive Landscape Planning

    Directory of Open Access Journals (Sweden)

    Pang Chan


    Full Text Available Using landscape objects with geo-visualisation tools to create 3D virtual environments is becoming one of the most prominent communication techniques to understand landscape form, function and processes. Geo-visualisation tools can also provide useful participatory planning support systems to explore current and future environmental issues such as biodiversity loss, crop failure, competing pressures on water availability and land degradation. These issues can be addressed by understanding them in the context of their locality. In this paper we discuss some of the technologies which facilitate our work on the issues of sustainability and productivity, and ultimately support for planning and decision-making. We demonstrate an online Landscape Object Library application with a suite of geo-visualisation tools to support landscape planning. This suite includes: a GIS based Landscape Constructor tool, a modified version of a 3D game engine SIEVE (Spatial Information Exploration and Visualisation Environment and an interactive touch table display. By integrating the Landscape Object Library with this suite of geo-visualisation tools, we believe we developed a tool that can support a diversity of landscape planning activities. This is illustrated by trial case studies in biolink design, whole farm planning and renewable energy planning. We conclude the paper with an evaluation of our Landscape Object Library and the suite of geographical tools, and outline some further research directions.

  4. Editorial: Mapping the Intellectual Landscape of Landscape and Urban Planning (United States)

    Paul H. Gobster; Wei-Ning. Xiang


    Maps are central to our understanding of landscapes. When this Editorship began to revise the journal's Aims and Scope for presentation in a forthcoming editorial, we sought ways in which we could identify the core knowledge base and boundaries, however permeable, of what the journal community considers to be Landscape and Urban Planning (LAND). Strategically, we...

  5. Landscape Painting in Evaluation of Changes in Landscape

    Czech Academy of Sciences Publication Activity Database

    Lacina, Jan; Halas, Petr


    Roč. 8, č. 2 (2015), s. 60-68 ISSN 1803-2427 Institutional support: RVO:68145535 Keywords : landscape painting * landscape ecology * land-use changes * biodiversity Subject RIV: DE - Earth Magnetism, Geodesy, Geography xml

  6. Fire Regime along Latitudinal Gradients of Continuous to Discontinuous Coniferous Boreal Forests in Eastern Canada

    Directory of Open Access Journals (Sweden)

    Jeanne Portier


    Full Text Available Fire is the main disturbance in North American coniferous boreal forests. In Northern Quebec, Canada, where forest management is not allowed, the landscape is gradually constituted of more opened lichen woodlands. Those forests are discontinuous and show a low regeneration potential resulting from the cumulative effects of harsh climatic conditions and very short fire intervals. In a climate change context, and because the forest industry is interested in opening new territories to forest management in the north, it is crucial to better understand how and why fire risk varies from the north to the south at the transition between the discontinuous and continuous boreal forest. We used time-since-fire (TSF data from fire archives as well as a broad field campaign in Quebec’s coniferous boreal forests along four north-south transects in order to reconstruct the fire history of the past 150 to 300 years. We performed survival analyses in each transect in order to (1 determine if climate influences the fire risk along the latitudinal gradient; (2 fractionate the transects into different fire risk zones; and (3 quantify the fire cycle—defined as the time required to burn an area equivalent to the size of the study area—of each zone and compare its estimated value with current fire activity. Results suggest that drought conditions are moderately to highly responsible for the increasing fire risk from south to north in the three westernmost transects. No climate influence was observed in the last one, possibly because of its complex physical environment. Fire cycles are shortening from south to north, and from east to west. Limits between high and low fire risk zones are consistent with the limit between discontinuous and continuous forests, established based on recent fire activity. Compared to the last 40 years, fire cycles of the last 150–300 years are shorter. Our results suggest that as drought episodes are expected to become more frequent

  7. Intrinsically Disordered Energy Landscapes (United States)

    Chebaro, Yassmine; Ballard, Andrew J.; Chakraborty, Debayan; Wales, David J.


    Analysis of an intrinsically disordered protein (IDP) reveals an underlying multifunnel structure for the energy landscape. We suggest that such ‘intrinsically disordered’ landscapes, with a number of very different competing low-energy structures, are likely to characterise IDPs, and provide a useful way to address their properties. In particular, IDPs are present in many cellular protein interaction networks, and several questions arise regarding how they bind to partners. Are conformations resembling the bound structure selected for binding, or does further folding occur on binding the partner in a induced-fit fashion? We focus on the p53 upregulated modulator of apoptosis (PUMA) protein, which adopts an -helical conformation when bound to its partner, and is involved in the activation of apoptosis. Recent experimental evidence shows that folding is not necessary for binding, and supports an induced-fit mechanism. Using a variety of computational approaches we deduce the molecular mechanism behind the instability of the PUMA peptide as a helix in isolation. We find significant barriers between partially folded states and the helix. Our results show that the favoured conformations are molten-globule like, stabilised by charged and hydrophobic contacts, with structures resembling the bound state relatively unpopulated in equilibrium.

  8. Urban landscape as palimpsest

    Directory of Open Access Journals (Sweden)

    Daniel-Gabriel Vâlceanu


    Full Text Available The current urban morphology and the identity building of the city construction can be designed as a palimpsest; the spatial development stages of urban systems represent the result of their evolution over time. The characteristics of urban palimpsest depend mainly on the emergent factors that influenced the territorial dynamics and the configuration of urban bodies. Urban life and its quality are directly influenced by spatial and temporal factors of the city evolution. For this reason the study aims to achieve a research to explain the concept of urban palimpsest and the current morphology of urban tissue because they are products of landscape transformations along the history. The current knowledge on urban palimpsest characteristics is very important and useful to plan the current and future evolution of urban systems. The case study presents a vast view on the history of spatial development and urban system as well as a dynamics of the landscape interconditioned by the elements of such development in the context of reference historical eras.

  9. Urban landscape as palimpsest

    Directory of Open Access Journals (Sweden)

    Daniel-Gabriel Vâlceanu


    Full Text Available The current urban morphology and the identity building of the city construction can be designed as a palimpsest; the spatial development stages of urban systems represent the result of their evolution over time. The characteristics of urban palimpsest depend mainly on the emergent factors that influenced the territorial dynamics and the configuration of urban bodies. Urban life and its quality are directly influenced by spatial and temporal factors of the city evolution. For this reason the study aims to achieve a research to explain the concept of urban palimpsest and the current morphology of urban tissue because they are products of landscape transformations along the history. The current knowledge on urban palimpsest characteristics is very important and useful to plan the current and future evolution of urban systems. The case study presents a vast view on the history of spatial development and urban system as well as a dynamics of the landscape interconditioned by the elements of such development in the context of reference historical eras

  10. Cultural Landscape and Migration

    Directory of Open Access Journals (Sweden)

    Gunnar Haaland


    Full Text Available This paper focus on the way Nepalese migrants in Myanmar use features of the natural environment in their homeland in metaphoric constructions of a cultural landscape expressing ethnic identity. It is through such "symbolic work" that perceptions of "ethnoscapes" are shaped and indoctrinated. Although the appeal is to symbols that can serve to foster the importance of Nepaliness as a basis for belonging to an imagined community, this does not mean that the caste/ethnicity interaction boundaries are broken down. It does mean however that sectors of activities where such boundaries are made relevant have been changed and so has the cultural content organized through such interaction boundaries. Ethnoscapes do not exist by themselves from a 'primordial' past; they require ongoing expression and confirmation. Features of a natural environment most migrants have never seen is used as sources for spinning compelling webs of significance extolling the values of belonging to a group that shares a common past in that environment. I shall here present material of an ethnoscape very different from what is experienced in Nepal, namely Nepalese multi-caste/ethnic communities among Kachins, Shans, Burmese, Indian and Chinese traders in the Kachin state of Northern Myanmar. Keywords: Nepali migrants; Myanmar; ethnic identity; cultural landscape DOI: 10.3126/dsaj.v4i0.4515 Dhaulagiri Journal of Sociology and Anthropology Vol.4 2010 pp.99-110

  11. Sustainability, Smart Growth, and Landscape Architecture (United States)

    Sustainability, Smart Growth, and Landscape Architecture is an overview course for landscape architecture students interested in sustainability in landscape architecture and how it might apply to smart growth principles in urban, suburban, and rural areas

  12. Landscape ecology and forest management (United States)

    Thomas R. Crow


    Almost all forest management activities affect landscape pattern to some extent. Among the most obvious impacts are those associated with forest harvesting and road building. These activities profoundly affect the size, shape, and configuration of patches in the landscape matrix. Even-age management such as clearcutting has been applied in blocks of uniform size, shape...

  13. Future landscapes: opportunities and challenges (United States)

    John Stanturf


    The global magnitude of degraded and deforested areas is best approached by restoring landscapes. Heightened international perception of the importance of forests and trees outside forests (e.g., woodlands, on farms) demands new approaches to future landscapes. The current need for forest restoration is two billion ha; most opportunities are mosaic restoration in the...

  14. Maintenance Sourcebook: Landscaping and Grounds. (United States)

    Macht, Carol; Gomulka, Ken; Harper, Wayne; Conry, Terry


    Asserts that facility managers need continual education in many subjects to keep their campuses in excellent condition, highlighting four areas related to landscaping and maintenance: landscaping care; athletic field care; grounds care; and equipment care. Lists of relevant professional organizations are included. (SM)

  15. Landscaping With Maintenance in Mind. (United States)

    Sorensen, Randy


    Examines school ground landscape design that enhances attractive of the school and provides for easier maintenance. Landscape design issues discussed include choice of grass, trees, and shrubs; irrigation; and safety and access. Other considerations for lessening maintenance problems for facility managers are also highlighted. (GR)

  16. The task of landscape ecology

    NARCIS (Netherlands)

    Barendregt, A.; Jongman, R.H.G.; Smidt, de J.; Wassen, M.


    This final chapter is a personal reflection of the authors on this book. To find an answer to the question what the task is of landscape ecology, we split the question in two parts. The first past of the question is about science for society: what is the task of landscape ecology in a changing

  17. Caribbean landscapes and their biodiversity (United States)

    A. E. Lugo; E. H. Helmer; E. Santiago Valentín


    Both the biodiversity and the landscapes of the Caribbean have been greatly modified as a consequence of human activity. In this essay we provide an overview of the natural landscapes and biodiversity of the Caribbean and discuss how human activity has affected both. Our Caribbean geographic focus is on the insular Caribbean and the biodiversity focus is on the flora,...

  18. Ervin Zube and landscape architecture (United States)

    Paul H. Gobster


    As he grew in his knowledge about the landscape through his involvemment in it as a person, student, practitioner, teacher, program director, and researcher, Ervin Zube's ideas about what landscape architecture is and should be continually evolved. He was a prolific writer whose publications span a broad range of audiences, and his contributions to ...

  19. The integrated landscape assessment project (United States)

    Miles A. Hemstrom; Janine Salwasser; Joshua Halofsky; Jimmy Kagan; Cyndi Comfort


    The Integrated Landscape Assessment Project (ILAP) is a three-year effort that produces information, models, data, and tools to help land managers, policymakers, and others examine mid- to broad-scale (e.g., watersheds to states and larger areas) prioritization of land management actions, perform landscape assessments, and estimate potential effects of management...

  20. Contingent Diversity on Anthropic Landscapes

    Directory of Open Access Journals (Sweden)

    William Balée


    Full Text Available Behaviorally modern human beings have lived in Amazonia for thousands of years. Significant dynamics in species turnovers due to human-mediated disturbance were associated with the ultimate emergence and expansion of agrarian technologies in prehistory. Such disturbances initiated primary and secondary landscape transformations in various locales of the Amazon region. Diversity in these locales can be understood by accepting the initial premise of contingency, expressed as unprecedented human agency and human history. These effects can be accessed through the archaeological record and in the study of living languages. In addition, landscape transformation can be demonstrated in the study of traditional knowledge (TK. One way of elucidating TK distinctions between anthropic and nonanthropic landscapes concerns elicitation of differential labeling of these landscapes and more significantly, elicitation of the specific contents, such as trees, occurring in these landscapes. Freelisting is a method which can be used to distinguish the differential species compositions of landscapes resulting from human-mediated disturbance vs. those which do not evince records of human agency and history. The TK of the Ka’apor Indians of Amazonian Brazil as revealed in freelisting exercises shows differentiation of anthropogenic from high forests as well as a recognition of diversity in the anthropogenic forests. This suggests that the agents of human-mediated disturbance and landscape transformation in traditional Amazonia encode diversity and contingency into their TK, which encoding reflects past cultural influence on landscape and society over time.

  1. Landscape habitat suitability index software (United States)

    William D. Dijak; Chadwick D. Rittenhouse; Michael A. Larson; Frank R. III Thompson; Joshua J. Millspaugh


    Habitat suitability index (HSI) models are traditionally used to evaluate habitat quality for wildlife at a local scale. Rarely have such models incorporated spatial relationships of habitat components. We introduce Landscape HSImodels, a new Microsoft Windowst (Microsoft, Redmond, WA)-based program that incorporates local habitat as well as landscape-scale attributes...

  2. Historic Landscape Survey, Randolph AFB, Texas (United States)


    etc. in landscape architecture or landscape gardening. 3.2 Site and layout In historic landscape studies, the term “ landscape characteristic” has...tarian spaces were located at the edges of the cantonment and featured less decoration in both landscaping and architectural ornamentation. This spatial...level of planning and attention to architectural detailing that characterized the construction of Randolph Field was also extended to the landscape

  3. Historic Landscape Survey, Maxwell AFB, Alabama (United States)


    trend, event, etc. in landscape architecture or landscape gardening. 3.2 Site and layout In historic landscape studies, the term “ landscape ...TR-13-12 97 The circular layout and modern architecture of Area 1400 was complemented by an extensive landscape plan. Figure 91 is a vegetation...significant alteration) and applies to activities as diverse as community planning, engineering, architecture , and landscape architecture . Design

  4. Continuities and Discontinuities in Psychopathology between Childhood and Adult Life (United States)

    Rutter, Michael; Kim-Cohen, Julia; Maughan, Barbara


    The possible mechanisms involved in continuities and discontinuities in psychopathology between childhood and adult life are considered in relation to the findings from systematic, prospective, long-term longitudinal studies. Findings on schizophrenia, neurodevelopmental disorders, emotional disturbances, antisocial behaviour and substance abuse…

  5. Continuities and Discontinuities in Family Members' Relationships with Alzheimer's Patients. (United States)

    Chesla, Catherine; And Others


    Asked 30 families who cared for family member with Alzheimer's disease to provide narratives of daily care over 18 months. Found that different family members experienced their relationship with Alzheimer's disease patient to be continuous, continuous but transformed, or radically discontinuous with their relationship prior to the disease.…

  6. The Age of Discontinuity; Guidelines to Our Changing Society. (United States)

    Drucker, Peter F.

    Concentrating on the social dimension of human experience and existence, this book probes certain profound changes occurring in contemporary technology, economy, society, politics, and education. The author discusses four major discontinuities: (1) the impact of the new technology on the industrial structure; (2) the shift from an "international…

  7. Predictors of benzodiazepine discontinuation in subjects manifesting complicated dependence. (United States)

    Vorma, Helena; Naukkarinen, Hannu H; Sarna, Seppo J; Kuoppasalmi, Kimmo I


    We described characteristics of subjects with benzodiazepine dependence that was typically complicated by harmful and hazardous alcohol use or high benzodiazepine doses, and assessed predictors of successful discontinuation of benzodiazepines for this group. Seventy-six patients who participated in a randomized clinical trial of two different gradual withdrawal treatment approaches were assessed. The trial was conducted between February 1995 and July 1999. The mean age +/- SD of subjects was 40.0 +/- 9.6 years, 55% were male, 38% were married or cohabiting, and 70% had received more than nine years of education. The median benzodiazepine dose was 35 mg/day (range 2.5-180) in diazepam equivalents. The median duration of benzodiazepine use was 84 (range 8-360) months. Subjects with lower benzodiazepine doses and no previous withdrawal attempts were more successful at benzodiazepine discontinuation. Cluster B personality/borderline personality disorder was associated with an inability to stop benzodiazepine use and with "dropping out" of treatment. Alcohol use-related disorders or other psychiatric diagnoses were not associated with outcome. Further studies on predictors of successful benzodiazepine discontinuation in different populations are required. Patients manifesting cluster B personality/borderline personality disorder and benzodiazepine dependence may need concomitant treatment for their personality disorders to benefit from benzodiazepine discontinuation treatment.

  8. Continuities and discontinuities in colonial West Africa: economic ...

    African Journals Online (AJOL)

    Continuities and discontinuities in colonial West Africa: economic activity in Dikwa division, 1922-1960. R Anthony Goodridge. Abstract. No Abstract. African Studies Monographs Serial No VII, 2006: 1-62. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  9. Space-time discontinuous Galerkin method for compressible flow

    NARCIS (Netherlands)

    Klaij, C.M.


    The space-time discontinuous Galerkin method allows the simulation of compressible flow in complex aerodynamical applications requiring moving, deforming and locally refined meshes. This thesis contains the space-time discretization of the physical model, a fully explicit solver for the resulting

  10. Premature Discontinuation in Adult Psychotherapy: A Meta-Analysis (United States)

    Swift, Joshua K.; Greenberg, Roger P.


    Objective: Premature discontinuation from therapy is a widespread problem that impedes the delivery of otherwise effective psychological interventions. The most recent comprehensive review found an average dropout rate of 47% across 125 studies (Wierzbicki & Pekarik, 1993); however, given a number of changes in the field over the past 2 decades,…

  11. Traces of an Early Learned Second Language in Discontinued Bilingualism (United States)

    Sadat, Jasmin; Pureza, Rita; Alario, F.-Xavier


    Can an early learned second language influence speech production after living many years in an exclusively monolingual environment? To address this issue, we investigated the consequences of discontinued early bilingualism in heritage speakers who moved abroad and switched language dominance from the second to the primary learned language. We used…

  12. Interface controlled growth of nanostructures in discontinuous Ag ...

    Indian Academy of Sciences (India)

    The first set of film–substrate interfaces consisted of Ag and Au films grown on borosilicate glass and carbon coated Cu grids used as substrates. ... Ion beam sputter deposition; discontinuous thin films; Ag; Au; film–substrate interface. 1. Introduction ..... Precise control of the film–substrate interactions leads to a very large ...

  13. Effects of discontinuous magnetic permeability on magnetodynamic problems

    KAUST Repository

    Guermond, J.-L.


    A novel approximation technique using Lagrange finite elements is proposed to solve magneto-dynamics problems involving discontinuous magnetic permeability and non-smooth interfaces. The algorithm is validated on benchmark problems and is used for kinematic studies of the Cadarache von Kármán Sodium 2 (VKS2) experimental fluid dynamo. © 2011 Elsevier Inc.

  14. Discontinuous type of splenogonadal fusion syndrome with limb defects

    Directory of Open Access Journals (Sweden)

    Vivek Patre


    Full Text Available Splenogonadal fusion is a rare congenital anomaly. We report a case of discontinuous type of splenogonadal fusion with congenital malformation. We focused here to avoid unnecessary orchidectomy by cementing the base of preoperative scrotal ultrasonography, for paratesticular masses.

  15. Discontinuous Galerkin error estimation for linear symmetrizable hyperbolic systems

    NARCIS (Netherlands)

    Adjerid, Slimane; Weinhart, Thomas


    We present an a posteriori error analysis for the discontinuous Galerkin discretization error of first-order linear symmetrizable hyperbolic systems of partial differential equations with smooth solutions. We perform a local error analysis by writing the local error as a series and showing that its

  16. Dialogic Reverberations: Police, Domestic Abuse, and the Discontinuance of Cases (United States)

    Lea, Susan J.; Lynn, Nick


    This study investigated the social construction of domestic abuse by police officers, specifically in the context of arguments presented to the prosecutor for a decision on whether to proceed with or discontinue the case. Nineteen police files were examined with a particular focus on the MG3, the "Report to Crown Prosecutors for Charging…

  17. Active postoperative acromegaly: sustained remission after discontinuation of somatostatin analogues

    Directory of Open Access Journals (Sweden)

    Cristina Alvarez-Escola


    Full Text Available In patients with active acromegaly after pituitary surgery, somatostatin analogues are effective in controlling the disease and can even be curative in some cases. After treatment discontinuation, the likelihood of disease recurrence is high. However, a small subset of patients remains symptom-free after discontinuation, with normalized growth hormone (GH and insulin-like growth factor (IGF1 levels. The characteristics of patients most likely to achieve sustained remission after treatment discontinuation are not well understood, although limited evidence suggests that sustained remission is more likely in patients with lower GH and IGF1 levels before treatment withdrawal, in those who respond well to low-dose treatment, in those without evidence of adenoma on an MRI scan and/or in patients who receive long-term treatment. In this report, we describe the case of a 56-year-old female patient treated with lanreotide Autogel for 11 years. Treatment was successfully discontinued, and the patient is currently disease-free on all relevant parameters (clinical, biochemical and tumour status. The successful outcome in this case adds to the small body of literature suggesting that some well-selected patients who receive long-term treatment with somatostatin analogues may achieve sustained remission.

  18. Local discontinuous Galerkin methods for phase transition problems

    NARCIS (Netherlands)

    Tian, Lulu


    In this thesis we develop a local discontinuous Galerkin (LDG) finite element method to solve mathematical models for phase transitions in solids and fluids. The first model we study is called a viscosity-capillarity (VC) system associated with phase transitions in elastic bars and Van der Waals

  19. Apnoea of prematurity – discontinuation of methylxanthines in a ...

    African Journals Online (AJOL)

    Background. Methylxanthines such as caffeine have been proven to reduce apnoea of prematurity and are often discontinued at 35 weeks' corrected gestational age (GA). Objective. To ascertain whether a caffeine protocol based on international guidelines is applicable in our setting, where GA is often uncertain. Methods.

  20. Boston Naming Test Discontinuation Rule: "Rigorous" versus "Lenient" Interpretations. (United States)

    Ferman, Tanis J.; Ivnik, Robert J.; Lucas, John A.


    Two interpretations of the Boston Naming Test (BNT) (E. Kaplan, H. Goodglass, and S. Weintraub, 1983) discontinuation rule of six consecutive failures were found in BNT use with 655 normal older adults and 140 people with Alzheimer's disease. Differences between lenient and rigorous interpretations of responses could have impact on…

  1. Consequence of Schooling: Cultural Discontinuity amongst the Inuit. (United States)

    Williamson, Karla Jessen


    Discusses factors related to cultural discontinuity (concept of human existence, souls and naming practices, importance of children) and their effects on the school system. Emphasizes importance of school authorities to understand the total Inuit traditional culture to make education more relevant to Inuit youth. (NEC)

  2. Continuity and discontinuity in the Inuit culture of Greenland

    NARCIS (Netherlands)

    Kylstra, Hans P.


    In november 1976 the Arctic Centre of the University of Gronlngen organized its third symposium. The third symposium was a Dutch-Danish one on the Greenlandic Inuit: 'Continuity and Discontinuity In Greenlandic Arctic Culture'. As on the two previous occasions, an exhibition was organized.

  3. 39 CFR 241.3 - Discontinuance of post offices. (United States)


    ....3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION ESTABLISHMENT... to the discontinued post office. (ii) If the ZIP Code is changed and the parent post office covers... Service Headquarters library. (g) Implementation of final determination—(1) Notice of final determination...

  4. 27 CFR 72.37 - Discontinuance of administrative proceedings. (United States)


    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Discontinuance of administrative proceedings. 72.37 Section 72.37 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... proceedings. If the petition is filed prior to administrative sale or retention for official use, proceedings...

  5. The Analysis of the Regression-Discontinuity Design in R (United States)

    Thoemmes, Felix; Liao, Wang; Jin, Ze


    This article describes the analysis of regression-discontinuity designs (RDDs) using the R packages rdd, rdrobust, and rddtools. We discuss similarities and differences between these packages and provide directions on how to use them effectively. We use real data from the Carolina Abecedarian Project to show how an analysis of an RDD can be…

  6. Discontinuous conduction mode analysis of phase-modulated series ...

    Indian Academy of Sciences (India)

    Utsab Kundu

    Discontinuous conduction mode (DCM); phase modulation; series resonant converter (SRC); time domain analysis; frequency domain ... tank energy is dissipated in MOSFET on resistances and effective series resistance (ESR) of tank ... quency square/quasi-square wave to excite the resonant tank. The tank comprises two ...

  7. An implicit discontinuous Galerkin finite element model for water waves

    NARCIS (Netherlands)

    van der Vegt, Jacobus J.W.; Ambati, V.R.; Bokhove, Onno


    We discuss a new higher order accurate discontinuous Galerkin finite element method for non-linear free surface gravity waves. The algorithm is based on an arbitrary Lagrangian Eulerian description of the flow field using deforming elements and a moving mesh, which makes it possible to represent

  8. Role of diffusional coherency strain theory in the discontinuous ...

    Indian Academy of Sciences (India)


    Role of diffusional coherency strain theory in the discontinuous precipitation in Mg–Al alloy. K T KASHYAP*, C RAMACHANDRA, M SUJATHA and B CHATTERJI. Central Materials and Processes Laboratory, Foundry & Forge Division, Hindustan Aeronautics Ltd., Bangalore 560 017,. India. MS received 24 August 1999; ...

  9. Data-oriented parsing with discontinuous constituents and function tags

    Directory of Open Access Journals (Sweden)

    Andreas van Cranenburgh


    Full Text Available Statistical parsers are e ective but are typically limited to producing projective dependencies or constituents. On the other hand, linguisti- cally rich parsers recognize non-local relations and analyze both form and function phenomena but rely on extensive manual grammar development. We combine advantages of the two by building a statistical parser that produces richer analyses. We investigate new techniques to implement treebank-based parsers that allow for discontinuous constituents. We present two systems. One system is based on a string-rewriting Linear Context-Free Rewriting System (LCFRS, while using a Probabilistic Discontinuous Tree Substitution Grammar (PDTSG to improve disambiguation performance. Another system encodes the discontinuities in the labels of phrase structure trees, allowing for efficient context-free grammar parsing.The two systems demonstrate that tree fragments as used in tree-substitution grammar improve disambiguation performance while capturing non-local relations on an as-needed basis. Additionally, we present results of models that produce function tags, resulting in a more linguistically adequate model of the data. We report substantial accuracy improvements in discontinuous parsing for German, English, and Dutch, including results on spoken Dutch.

  10. Continuity and Discontinuity in Early Christian Apologetics, Preface

    DEFF Research Database (Denmark)

    Jacobsen, Anders-Christian


    Continuity and Discontinuity in Early Christian Apologetics indeholder bidrag til en workshop om apologetik i den tidlige kristendom, der blev afholdt i Oxford i sommeren 2007. Her deltog forskere fra Tyskland, Finland og Danmark med det formål at præsentere og diskutere nogle af de resultater og...

  11. AED discontinuation may be dangerous for seizure-free patients. (United States)

    Schmidt, Dieter


    Despite its benefits, stopping antiepileptic drugs (AEDs) in seizure-free patients is associated with several risks. AED discontinuation doubles the risk of seizure recurrence for up to 2 years compared with continued treatment. On average, one in three patients has a seizure recurrence, though the range can go up to 66% (34%, range 12-66%, 95% CI: 27-43). Furthermore, the outcome of treating a seizure recurrence in patients who have been seizure-free for years is surprisingly poor in some patients. Although the long-term prognosis is not worsened by drug discontinuation, one in five patients does not re-enter remission and for some patients, it may take several years to become seizure-free again. The risk of seizure recurrence is particularly high for those with juvenile myoclonic epilepsy and symptomatic focal epilepsy, the most frequent epilepsies in adults. Seizure-recurrence may have devastating, medical, psychological and social consequences for the individual, for example injury, loss of self-esteem, unemployment and losing a driver's license. Discontinuation should be avoided in patients with a high risk of seizure recurrence. Given these risks, patients will ultimately have to decide themselves whether they wish to discontinue drug treatment after full informed consent.

  12. A Note on Stress Function Discontinuities in Plane Plastic Bending ...

    African Journals Online (AJOL)

    The variational and differential equation formulations of the stress function problem for combined plane bending and torsion of a fully plastic material are discussed. The nature of discontinuities to be expected as well as the actual degree of correspondence between the two formulations is determined. A modification of the ...

  13. Phase discontinuity predictions using a machine-learning trained kernel

    NARCIS (Netherlands)

    Sawaf, F.; Groves, R.M.


    Phase unwrapping is one of the key steps of interferogram analysis, and its accuracy relies primarily on the correct identification of phase discontinuities. This can be especially challenging for inherently noisy phase fields, such as those produced through shearography and other speckle-based


    Directory of Open Access Journals (Sweden)

    Trubitsyna Natalja Anatolevna


    Full Text Available The article discusses the interaction between the wind regime and the landscape. Examples of objects of landscape architecture in high-tech and science-intensive spheres, such as the launch pad of a spacecraft, are given. Wind protection is represented as a result of work on wind power engineering and a means of increasing bioclimatic comfort. The terms of landscape architecture are disclosed and mutual influence on the climate and impact on woody-shrub vegetation and field crops are analyzed. The phenomenon of air permeability for optimal operation of windproof structures and orientations of geoplastics and dendroplastics is described. In this paper, a classification of terrain types is described with a description of their elemental composition, as well as various categories of landscape. The proposal to consider the landscape as a territorial complex, and landscape buildings, landscape-architectural structures as objects of landscape architecture possessing properties of wind protection and air permeability was introduced. Thus, the concept of a landscape-architectural complex as a single group of landscape-architectural objects located on the territory and connected by a common system of communications, functions, technical elements and a visual image is formulated. Further research is based on the rationale for the use of the term ensemble in relation to the objects of the landscape and architectural complex and the identification of their design and planning features that can affect the parameters of wind protection and air permeability. The paper concludes that frequent coincidence of favorable for the fauna wind regime and mimicry of landscape architecture objects. The combination in the landscape of functions for wind protection and aesthetics is analyzed with analysis of such elements of landscape architecture as hedges and windproof properties of green plantations. In the work examples of wind engineering small architectural forms are

  15. Fitness Landscapes of Functional RNAs

    Directory of Open Access Journals (Sweden)

    Ádám Kun


    Full Text Available The notion of fitness landscapes, a map between genotype and fitness, was proposed more than 80 years ago. For most of this time data was only available for a few alleles, and thus we had only a restricted view of the whole fitness landscape. Recently, advances in genetics and molecular biology allow a more detailed view of them. Here we review experimental and theoretical studies of fitness landscapes of functional RNAs, especially aptamers and ribozymes. We find that RNA structures can be divided into critical structures, connecting structures, neutral structures and forbidden structures. Such characterisation, coupled with theoretical sequence-to-structure predictions, allows us to construct the whole fitness landscape. Fitness landscapes then can be used to study evolution, and in our case the development of the RNA world.

  16. Evaluation principles in Landscape Projects

    Directory of Open Access Journals (Sweden)

    Saverio Miccoli


    Full Text Available Landscape is a crucial component of the world heritage. Landscape projects play a vital role in the development of sustainable scenarios. The assessment of a project plays a dual role: it is a procedure to pass judgements on both “values” and “choices”. From a strictly economic perspective, the community’s appreciation of Landscape Projects may be ascertained through its “total economic value”. The value of a Landscape Project may be ascertained also through a multidimensional approach, based on the analysis of different project attributes whose outcome is calculated in non-monetary terms. This paper illustrates the cultural foundations and theoretical-methodological principles to assess Landscape Projects.

  17. Evaluation principles in Landscape Projects

    Directory of Open Access Journals (Sweden)

    Saverio Miccoli


    Full Text Available Landscape is a crucial component of the world heri- tage. Landscape projects play a vital role in the development of sustainable scenarios. The assessment of a project plays a dual role: it is a procedure to pass judgements on both “values” and “choices”. From a strictly economic perspective, the community’s appreciation of Landscape Projects may be ascertained through its “total economic value”. The value of a Landscape Project may be ascertained also through a multidimensional approach, based on the analysis of different project attributes whose outcome is calculated in non-monetary terms. This paper illustrates the cultural foundations and theoretical-methodological principles to assess Landscape Projects.

  18. Research Methods in Landscape Perception and Experience

    NARCIS (Netherlands)

    Karmanov, D.Y.


    Experiencing nature, landscape and heritage, first chapter. Karmanov provides a general overview of methods of studying landscape perceptions, illustrated by a wide variety of mainly experimental psychological research.

  19. Error Analysis for Discontinuous Galerkin Method for Parabolic Problems (United States)

    Kaneko, Hideaki


    In the proposal, the following three objectives are stated: (1) A p-version of the discontinuous Galerkin method for a one dimensional parabolic problem will be established. It should be recalled that the h-version in space was used for the discontinuous Galerkin method. An a priori error estimate as well as a posteriori estimate of this p-finite element discontinuous Galerkin method will be given. (2) The parameter alpha that describes the behavior double vertical line u(sub t)(t) double vertical line 2 was computed exactly. This was made feasible because of the explicitly specified initial condition. For practical heat transfer problems, the initial condition may have to be approximated. Also, if the parabolic problem is proposed on a multi-dimensional region, the parameter alpha, for most cases, would be difficult to compute exactly even in the case that the initial condition is known exactly. The second objective of this proposed research is to establish a method to estimate this parameter. This will be done by computing two discontinuous Galerkin approximate solutions at two different time steps starting from the initial time and use them to derive alpha. (3) The third objective is to consider the heat transfer problem over a two dimensional thin plate. The technique developed by Vogelius and Babuska will be used to establish a discontinuous Galerkin method in which the p-element will be used for through thickness approximation. This h-p finite element approach, that results in a dimensional reduction method, was used for elliptic problems, but the application appears new for the parabolic problem. The dimension reduction method will be discussed together with the time discretization method.

  20. Clopidogrel discontinuation and platelet reactivity following coronary stenting

    LENUS (Irish Health Repository)


    Summary. Aims: Antiplatelet therapy with aspirin and clopidogrel is recommended for 1 year after drug-eluting stent (DES) implantation or myocardial infarction. However, the discontinuation of antiplatelet therapy has become an important issue as recent studies have suggested a clustering of ischemic events within 90 days of clopidogrel withdrawal. The objective of this investigation was to explore the hypothesis that there is a transient ‘rebound’ increase in platelet reactivity within 3 months of clopidogrel discontinuation. Methods and Results: In this prospective study, platelet function was assessed in patients taking aspirin and clopidogrel for at least 1 year following DES implantation. Platelet aggregation was measured using a modification of light transmission aggregometry in response to multiple concentrations of adenosine diphosphate (ADP), epinephrine, arachidonic acid, thrombin receptor activating peptide and collagen. Clopidogrel was stopped and platelet function was reassessed 1 week, 1 month and 3 months later. Thirty-two patients on dual antiplatelet therapy were recruited. Discontinuation of clopidogrel increased platelet aggregation to all agonists, except arachidonic acid. Platelet aggregation in response to ADP (2.5, 5, 10, and 20 μm) and epinephrine (5 and 20 μm) was significantly increased at 1 month compared with 3 months following clopidogrel withdrawal. Thus, a transient period of increased platelet reactivity to both ADP and epinephrine was observed 1 month after clopidogrel discontinuation. Conclusions: This study demonstrates a transient increase in platelet reactivity 1 month after clopidogrel withdrawal. This phenomenon may, in part, explain the known clustering of thrombotic events observed after clopidogrel discontinuation. This observation requires confirmation in larger populations.

  1. Reasons given by mothers for discontinuing breastfeeding in Iran

    Directory of Open Access Journals (Sweden)

    Olang Beheshteh


    Full Text Available Abstract Background We have previously shown that in Iran, only 28% of infants were exclusively breastfed at six months, despite a high prevalence of breastfeeding at two years of age. The primary aim of this study was to investigate the reasons women discontinued exclusive breastfeeding. Method This retrospective study was based on questionnaires and interviews with 63,071 mothers of infants up to 24 months of age, divided into two populations: infants younger than six months and six months or older. The data were collected in 2005–2006 from all 30 provinces of Iran. Results Only 5.3% of infants less than six months of age stopped breastfeeding (mean age of 3.2 months; more commonly in urban than rural areas. The most frequently cited reasons mothers gave for discontinuing exclusive breastfeeding were physicians’ recommendation (54% and insufficient breast milk (self-perceived or true, 28%. Breastfeeding was common after six months of age: only 11% of infants discontinued breastfeeding, at a mean of 13.8 months. The most common reason for discontinuation at this age was insufficient breast milk (self-perceived or true, 45%. Maternal illness or medication (10%, infant illness (6%, and return to work (3% were uncommon causes. Use of a pacifier was correlated with breastfeeding discontinuation. Maternal age and education was not associated with duration of breastfeeding. Multivariate analysis showed that using a pacifier and formula or other bottle feeding increased the risk of early cessation of breastfeeding. Conclusions Physicians and other health professionals have an important role to play in encouraging and supporting mothers to maintain breastfeeding.

  2. A Classification of Landscape Services to Support Local Landscape Planning

    Directory of Open Access Journals (Sweden)

    María Vallés-Planells


    Full Text Available The ecosystem services approach has been proven successful to measure the contributions of nature and greenery to human well-being. Ecosystems have an effect on quality of life, but landscapes also, as a broader concept, may contribute to people's well-being. The concept of landscape services, compared to ecosystem services, involves the social dimension of landscape and the spatial pattern resulting from both natural and human processes in the provision of benefits for human-well being. Our aim is to develop a classification for landscape services. The proposed typology of services is built on the Common International Classification of Ecosystem Services (CICES and on a critical review of existing literature on human well-being dimensions, existing ecosystem service classifications, and landscape perception. Three themes of landscape services are defined, each divided into several groups: provisioning, regulation and maintenance, cultural and social life fulfillment, with the latter focusing on health, enjoyment, and personal and social fulfillment. A special emphasis is made on cultural services, which are especially important when applied to landscape and which have received less attention.

  3. Buildings Interoperability Landscape

    Energy Technology Data Exchange (ETDEWEB)

    Hardin, Dave [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Stephan, Eric G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wang, Weimin [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Corbin, Charles D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Widergren, Steven E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)


    Through its Building Technologies Office (BTO), the United States Department of Energy’s Office of Energy Efficiency and Renewable Energy (DOE-EERE) is sponsoring an effort to advance interoperability for the integration of intelligent buildings equipment and automation systems, understanding the importance of integration frameworks and product ecosystems to this cause. This is important to BTO’s mission to enhance energy efficiency and save energy for economic and environmental purposes. For connected buildings ecosystems of products and services from various manufacturers to flourish, the ICT aspects of the equipment need to integrate and operate simply and reliably. Within the concepts of interoperability lie the specification, development, and certification of equipment with standards-based interfaces that connect and work. Beyond this, a healthy community of stakeholders that contribute to and use interoperability work products must be developed. On May 1, 2014, the DOE convened a technical meeting to take stock of the current state of interoperability of connected equipment and systems in buildings. Several insights from that meeting helped facilitate a draft description of the landscape of interoperability for connected buildings, which focuses mainly on small and medium commercial buildings. This document revises the February 2015 landscape document to address reviewer comments, incorporate important insights from the Buildings Interoperability Vision technical meeting, and capture thoughts from that meeting about the topics to be addressed in a buildings interoperability vision. In particular, greater attention is paid to the state of information modeling in buildings and the great potential for near-term benefits in this area from progress and community alignment.

  4. Data anonymization patent landscape

    Directory of Open Access Journals (Sweden)

    Mirjana Pejić Bach


    Full Text Available The omnipresent, unstoppable increase in digital data has led to a greater understanding of the importance of data privacy. Different approaches are used to implement data privacy. The goal of this paper is to develop a data anonymization patent landscape, by determining the following: (i the trend in data anonymization patenting, (ii the type of technical content protected in data anonymization, (iii the organizations and countries most active in patenting data anonymization know-how; and (iv the topics emerging most often in patent titles. Patents from the PatSeer database relating to data anonymization from 2001 to 2015 were analyzed. We used the longitudinal approach in combination with text mining techniques to develop a data anonymization patent landscape. The results indicated the following. The number of single patent families is growing with a high increase after 2010, thus indicating a positive trend in the area of patenting data anonymization solutions. The majority of patenting activities relate to the G Physics section. Organizations from the USA and Japan assigned the majority of patents related to data anonymization. The results of text mining indicate that the most often used word in titles of data anonymization patents are “anonym*, “method”, “data” and “system”. Several additional words that indicated the most frequent topics related to data anonymization were: “equipment”, “software”, “protection”, “identification”, or “encryption”, and specific topics such as “community”, “medical”, or “service”.

  5. Tracing Landscape Evolution of the Sila Massif using 10Be (United States)

    Raab, Gerald; Ruppli, Annina; Brandová, Dagmar; Scarciglia, Fabio; Norton, Kevin; Christl, Marcus; Egli, Markus


    Erosion distinctly shapes earth's surface and therefore influences landscape and, in particular, also soils. The evolution of landscapes and soils are known to evolve in discontinuous ways over thousands of years. Several studies have tried to compare erosion rates over different time periods, thereby trying to derive a chronology of process rates. These studies, however, often had a catchment-wide approach and, thus, basically lack in a distinction of soil erosion from erosion as a general landscape process. To decipher soil erosion rates over millennia time-scales, new approaches are therefore needed. Landscapes affected by intense erosion and denudation may be characterised by boulder fields or "tor" landforms, i.e. tower-like or dome-shaped, often castellated, residual rock boulders (resistant to erosion) "growing" from gentle landforms. Determining the speed of boulder exhumation, soil erosion rates over different time periods can be deduced. The Sila Massif upland plateau in Calabria (Italy) exhibits boulder fields that seemed to be exhumed over time. 10Be-dating along vertical profiles of such granitic boulders was now used as a new approach to unravel long-term erosional phases and to reconstruct the lowering of the surface. The results cover a time span of the last 140 ka and revealed several phases of their exhumation. The different trends could be connected to specific climate conditions, yet a major tectonic influence could be excluded, as the main uplift ended about 400 ka ago. This new approach provides a new insight into soil erosion and denudation rates during the Pleistocene and Holocene.

  6. Arroyo channel head evolution in a flash-flood-dominated discontinuous ephemeral stream system (United States)

    DeLong, Stephen B.; Johnson, Joel P.L.; Whipple, Kelin X.


    We study whether arroyo channel head retreat in dryland discontinuous ephemeral streams is driven by surface runoff, seepage erosion, mass wasting, or some combination of these hydrogeomorphic processes. We monitored precipitation, overland flow, soil moisture, and headcut migration over several seasonal cycles at two adjacent rangeland channel heads in southern Arizona. Erosion occurred by headward retreat of vertical to overhanging faces, driven dominantly by surface runoff. No evidence exists for erosion caused by shallow-groundwater–related processes, even though similar theater-headed morphologies are sometimes attributed to seepage erosion by emerging groundwater. At our field site, vertical variation in soil shear strength influenced the persistence of the characteristic theater-head form. The dominant processes of erosion included removal of grains and soil aggregates during even very shallow (1–3 cm) overland flow events by runoff on vertical to overhanging channel headwalls, plunge-pool erosion during higher-discharge runoff events, immediate postrunoff wet mass wasting, and minor intra-event dry mass wasting on soil tension fractures developing subparallel to the headwall. Multiple stepwise linear regression indicates that the migration rate is most strongly correlated with flow duration and total precipitation and is poorly correlated with peak flow depth or time-integrated flow depth. The studied channel heads migrated upslope with a self-similar morphologic form under a wide range of hydrological conditions, and the most powerful flash floods were not always responsible for the largest changes in landscape form in this environment. 

  7. Continuing Discontinuities: Local and State Perspectives on Cattle Production and Water Management in Botswana

    Directory of Open Access Journals (Sweden)

    Emmanuel Manzungu


    Full Text Available From 1885 when the modern state of Botswana was founded until the discovery of significant mineral deposits in 1967, one year after independence, the livestock industry, particularly cattle production, played a significant role in the country’s economy. Today there are concerns about how the livestock industry, because of its importance to many rural households, and its potential to diversify the mineral-dominated economy, can be revived. In recognition of the country’s semi-arid climate, the government has promoted a policy of developing water sources for livestock watering. The state has acknowledged the policy has largely been ineffective, but continues to implement it. This paper attempts to explain this paradox by examining state and local perspectives in the management of water and related resources in the Botswana part of the Limpopo river basin. The discontinuities between the local inhabitants and state practitioners are analyzed within the wider physical social, political, and economic landscape. We ascribe the continued implementation of an ineffective policy to modernisation claims.

  8. Species Composition at the Sub-Meter Level in Discontinuous Permafrost in Subarctic Sweden (United States)

    Anderson, S. M.; Palace, M. W.; Layne, M.; Varner, R. K.; Crill, P. M.


    Northern latitudes are experiencing rapid warming. Wetlands underlain by permafrost are particularly vulnerable to warming which results in changes in vegetative cover. Specific species have been associated with greenhouse gas emissions therefore knowledge of species compositional shift allows for the systematic change and quantification of emissions and changes in such emissions. Species composition varies on the sub-meter scale based on topography and other microsite environmental parameters. This complexity and the need to scale vegetation to the landscape level proves vital in our estimation of carbon dioxide (CO2) and methane (CH4) emissions and dynamics. Stordalen Mire (68°21'N, 18°49'E) in Abisko and is located at the edge of discontinuous permafrost zone. This provides a unique opportunity to analyze multiple vegetation communities in a close proximity. To do this, we randomly selected 25 1x1 meter plots that were representative of five major cover types: Semi-wet, wet, hummock, tall graminoid, and tall shrub. We used a quadrat with 64 sub plots and measured areal percent cover for 24 species. We collected ground based remote sensing (RS) at each plot to determine species composition using an ADC-lite (near infrared, red, green) and GoPro (red, blue, green). We normalized each image based on a Teflon white chip placed in each image. Textural analysis was conducted on each image for entropy, angular second momentum, and lacunarity. A logistic regression was developed to examine vegetation cover types and remote sensing parameters. We used a multiple linear regression using forwards stepwise variable selection. We found statistical difference in species composition and diversity indices between vegetation cover types. In addition, we were able to build regression model to significantly estimate vegetation cover type as well as percent cover for specific key vegetative species. This ground-based remote sensing allows for quick quantification of vegetation

  9. Landscape characterization and biodiversity research

    Energy Technology Data Exchange (ETDEWEB)

    Dale, V.H. [Oak Ridge National Lab., TN (United States); Offerman, H. [Univ. of Maryland, College Park, MD (United States). Geography Dept.; Frohn, R. [Univ. of California, Santa Barbara, CA (United States); Gardner, R.H. [Appalachian Environmental Lab., Frostburg, MD (United States)


    Rapid deforestation often produces landscape-level changes in forest characteristics and structure, including area, distribution, and forest habitat types. Changes in landscape pattern through fragmentation or aggregation of natural habitats can alter patterns of abundance for single species and entire communities. Examples of single-species effects include increased predation along the forest edge, the decline in the number of species with poor dispersal mechanisms, and the spread of exotic species that have deleterious effects (e.g., gypsy moth). A decrease in the size and number of natural habitat patches increases the probability of local extirpation and loss of diversity of native species, whereas a decline in connectivity between habitat patches can negatively affect species persistence. Thus, there is empirical justification for managing entire landscapes, not just individual habitat types, in order to insure that native plant and animal diversity is maintained. A landscape is defined as an area composed of a mosaic of interacting ecosystems, or patches, with the heterogeneity among the patches significantly affecting biotic and abiotic processes in the landscape. Patches comprising a landscape are usually composed of discrete areas of relatively homogeneous environmental conditions and must be defined in terms of the organisms of interest. A large body of theoretical work in landscape ecology has provided a wealth of methods for quantifying spatial characteristics of landscapes. Recent advances in remote sensing and geographic information systems allow these methods to be applied over large areas. The objectives of this paper are to present a brief overview of common measures of landscape characteristics, to explore the new technology available for their calculation, to provide examples of their application, and to call attention to the need for collection of spatially-explicit field data.

  10. Beyond Landscape MacArchitecture: new languages, new landscapes

    Directory of Open Access Journals (Sweden)

    Simon Rackham


    Full Text Available The sine qua non of landscape architecture is respect for the genius loci, but even in the landscape, as in architecture and society more generally, a process of cultural homogenisation has been taking place. Against this process, a resurgence of interest in minority languages in Europe can be seen as an assertion of pride, and a desire to preserve difference. In Scotland, landscape architects are attempting to reinterpret Scottish and northern European urban design influences and materials: in effect to develop a new regional dialect for the new landscapes. Rooted in sound design principles and materials which respond to and reflect the climate, way of life and traditions of the place, design languages can communicate effectively about cultural values and differences.

  11. Decision Making on Fitness Landscapes

    DEFF Research Database (Denmark)

    Arthur, Rudy; Sibani, Paolo


    We discuss fitness landscapes and how they can be modified to account for co-evolution. We are interested in using the landscape as a way to model rational decision making in a toy economic system. We develop a model very similar to the Tangled Nature Model of Christensen et. al. that we call...... the Tangled Decision Model. This is a natural setting for our discussion of co-evolutionary fitness landscapes. We use a Monte Carlo step to simulate decision making and investigate two different decision making procedures....

  12. Stability Landscape of Shell Buckling (United States)

    Virot, Emmanuel; Kreilos, Tobias; Schneider, Tobias M.; Rubinstein, Shmuel M.


    We measure the response of cylindrical shells to poking and identify a stability landscape, which fully characterizes the stability of perfect shells and imperfect ones in the case where a single defect dominates. We show that the landscape of stability is independent of the loading protocol and the poker geometry. Our results suggest that the complex stability of shells reduces to a low dimensional description. Tracking ridges and valleys of this landscape defines a natural phase-space coordinates for describing the stability of shells.

  13. Studying landscape architecture in Denmark

    DEFF Research Database (Denmark)

    Braae, Ellen Marie; Hare, Richard Andrew


    Landscape architecture is a well-established profession in Denmark. From the early 20th Century the profession developed steadily. However, it was 1960 before a separate education was established. This proved timely as the immense physical development of the Danish welfare state of the 1970s and 80......s demanded large numbers of landscape architects. Today landscape architecture education addresses current challenges of climate change and the need for sustainable development where an understanding of natural systems is seen as essential for future urbanisation processes in evermore innovative...

  14. Decision making on fitness landscapes (United States)

    Arthur, R.; Sibani, P.


    We discuss fitness landscapes and how they can be modified to account for co-evolution. We are interested in using the landscape as a way to model rational decision making in a toy economic system. We develop a model very similar to the Tangled Nature Model of Christensen et al. that we call the Tangled Decision Model. This is a natural setting for our discussion of co-evolutionary fitness landscapes. We use a Monte Carlo step to simulate decision making and investigate two different decision making procedures.

  15. Descision Making on Fitness Landscapes

    CERN Document Server

    Arthur, Rudy


    We discuss fitness landscapes and how they can be modified to account for co-evolution. We are interested in using the landscape as a way to model rational decision making in a toy economic system. We develop a model very similar to the Tangled Nature Model of Christensen et. al. that we call the Tangled Decision Model. This is a natural setting for our discussion of co-evolutionary fitness landscapes. We use a Monte Carlo step to simulate decision making and investigate two different decision making procedures.

  16. Connecting Brabant's cover sand landscapes through landscape history (United States)

    Heskes, Erik; van den Ancker, Hanneke; Jungerius, Pieter Dirk; Harthoorn, Jaap; Maes, Bert; Leenders, Karel; de Jongh, Piet; Kluiving, Sjoerd; van den Oetelaar, Ger


    Noord-Brabant has the largest variety of cover sand landscapes in The Netherlands, and probably in Western Europe. During the Last Ice Age the area was not covered by land ice and a polar desert developed in which sand dunes buried the existing river landscapes. Some of these polar dune landscapes experienced a geomorphological and soil development that remained virtually untouched up to the present day, such as the low parabolic dunes of the Strabrechtse Heide or the later and higher dunes of the Oisterwijkse Vennen. As Noord-Brabant lies on the fringe of a tectonic basin, the thickness of cover sand deposits in the Centrale Slenk, part of a rift through Europe, amounts up to 20 metres. Cover sand deposits along the fault lines cause the special phenomenon of 'wijst' to develop, in which the higher grounds are wetter than the boarding lower grounds. Since 4000 BC humans settled in these cover sand landscapes and made use of its small-scale variety. An example are the prehistoric finds on the flanks and the historic towns on top of the 'donken' in northwest Noord-Brabant, where the cover sand landscapes are buried by river and marine deposits and only the peaks of the dunes protrude as donken. Or the church of Handel that is built beside a 'wijst' source and a site of pilgrimage since living memory. Or the 'essen' and plaggen agriculture that developed along the stream valleys of Noord-Brabant from 1300 AD onwards, giving rise to geomorphological features as 'randwallen' and plaggen soils of more than a metre thickness. Each region of Brabant each has its own approach in attracting tourists and has not yet used this common landscape history to connect, manage and promote their territories. We propose a landscape-historical approach to develop a national or European Geopark Brabants' cover sand landscapes, in which each region focuses on a specific part of the landscape history of Brabant, that stretches from the Late Weichselian polar desert when the dune


    Directory of Open Access Journals (Sweden)

    Leonid Rudenko


    Full Text Available The paper presents the results of the first, in Ukraine; project on landscape planning widely accepted in European countries. Under the project implemented in 2010–2013, a landscape-planning program has been developed for the Cherkassy oblast. This is the first document of this kind in Ukraine. The program is mainly based on the experience of the German and Russian schools of landscape planning and on research and assessment conducted by the authors, which allowed identifying approaches to landscape planning, principles of the national policy, and characteristics and potential of environmentally friendly planning in Ukraine. The paper discusses the main phases of the work on the development of the landscape program for the oblast. It also identifies the main stages and key concepts and principles of landscape planning. The paper presents the results of integrated research on the identification and classification of conflicts in land use and the integral concept of the developmental goals for the oblast. The results can be the foundation for adopting management decisions and development of action plans for the lower hierarchal branches.

  18. Perspectives on landscape identity, a conceptual challenge

    NARCIS (Netherlands)

    Stobbelaar, D.J.; Pedroli, B.


    The concept of landscape identity is often referred to in landscape policy and planning. A clear definition of the concept is lacking however. This is problematic because the term ‘landscape identity’ can have many different meanings and thus easily lead to confusion. We define landscape identity as

  19. Bipolarity and Ambivalence in Landscape Architecture

    NARCIS (Netherlands)

    Koh, J.


    Our discipline of landscape architecture contains bipolarity, not only in terms of landscape and architecture but also because the idea of landscape is both aesthetic and scientific. Furthermore, within landscape architecture there is a gap between design (as implied by architecture) and planning

  20. Perspectives on landscape identity : a conceptual challenge

    NARCIS (Netherlands)

    Stobbelaar, D.J.; Pedroli, B.


    The concept of landscape identity is often referred to in landscape policy and planning. A clear definition of the concept is lacking however. This is problematic because the term ‘landscape identity’ can have many different meanings and thus easily lead to confusion. We define landscape identity as

  1. Identification of scenically preferred forest landscapes (United States)

    Roberta C. Patey; Richard M. Evans


    This study identified manipulated forest landscapes with a low understory shrub density as being esthetic-ally preferred over non-manipulated, dense understory landscapes. This landscape pattern was identified both qualitatively, by preference ratings of respondents, and quantitatively, by measuring the physical components of each landscape. Forest sites were selected...

  2. Landscape genomics: A brief perspective [Chapter 9 (United States)

    Michael K. Schwartz; Gordon Luikart; Kevin S. McKelvey; Samuel A. Cushman


    Landscape genetics is the amalgamation of population genetics and landscape ecology (see Manel et al. 2003; Storfer et al. 2007). In Chapter 17, we discuss landscape genetics and provide two examples of applications in the area of modeling population connectivity and inferring fragmentation. These examples, like virtually all extant landscape genetic analyses, were...

  3. Constitutive model of discontinuous plastic flow at cryogenic temperatures

    CERN Document Server

    Skoczen, B; Bielski, J; Marcinek, D


    FCC metals and alloys are frequently used in cryogenic applications, nearly down to the temperature of absolute zero, because of their excellent physical and mechanical properties including ductility. Some of these materials, often characterized by the low stacking fault energy (LSFE), undergo at low temperatures three distinct phenomena: dynamic strain ageing (DSA), plastic strain induced transformation from the parent phase (gamma) to the secondary phase (alpha) and evolution of micro-damage. The constitutive model presented in the paper is focused on the discontinuous plastic flow (serrated yielding) and takes into account the relevant thermodynamic background. The discontinuous plastic flow reflecting the DSA effect is described by the mechanism of local catastrophic failure of Lomer-Cottrell (LC) locks under the stress fields related to the accumulating edge dislocations (below the transition temperature from the screw dislocations to the edge dislocations mode T-1). The failure of LC locks leads to mass...

  4. The Gutenberg Discontinuity: Melt at the Lithosphere-Asthenosphere Boundary (United States)

    Schmerr, Nicholas


    The lithosphere-asthenosphere boundary (LAB) beneath ocean basins separates the upper thermal boundary layer of rigid, conductively cooling plates from the underlying ductile, convecting mantle. The origin of a seismic discontinuity associated with this interface, known as the Gutenberg discontinuity (G), remains enigmatic. High-frequency SS precursors sampling below the Pacific plate intermittently detect the G as a sharp, negative velocity contrast at 40- to 75-kilometer depth. These observations lie near the depth of the LAB in regions associated with recent surface volcanism and mantle melt production and are consistent with an intermittent layer of asthenospheric partial melt residing at the lithospheric base. I propose that the G reflectivity is regionally enhanced by dynamical processes that produce melt, including hot mantle upwellings, small-scale convection, and fluid release during subduction.

  5. Discontinuity Detection in the Shield Metal Arc Welding Process. (United States)

    Cocota, José Alberto Naves; Garcia, Gabriel Carvalho; da Costa, Adilson Rodrigues; de Lima, Milton Sérgio Fernandes; Rocha, Filipe Augusto Santos; Freitas, Gustavo Medeiros


    This work proposes a new methodology for the detection of discontinuities in the weld bead applied in Shielded Metal Arc Welding (SMAW) processes. The detection system is based on two sensors-a microphone and piezoelectric-that acquire acoustic emissions generated during the welding. The feature vectors extracted from the sensor dataset are used to construct classifier models. The approaches based on Artificial Neural Network (ANN) and Support Vector Machine (SVM) classifiers are able to identify with a high accuracy the three proposed weld bead classes: desirable weld bead, shrinkage cavity and burn through discontinuities. Experimental results illustrate the system's high accuracy, greater than 90% for each class. A novel Hierarchical Support Vector Machine (HSVM) structure is proposed to make feasible the use of this system in industrial environments. This approach presented 96.6% overall accuracy. Given the simplicity of the equipment involved, this system can be applied in the metal transformation industries.

  6. Reactive oxygen species production and discontinuous gas exchange in insects. (United States)

    Boardman, Leigh; Terblanche, John S; Hetz, Stefan K; Marais, Elrike; Chown, Steven L


    While biochemical mechanisms are typically used by animals to reduce oxidative damage, insects are suspected to employ a higher organizational level, discontinuous gas exchange mechanism to do so. Using a combination of real-time, flow-through respirometry and live-cell fluorescence microscopy, we show that spiracular control associated with the discontinuous gas exchange cycle (DGC) in Samia cynthia pupae is related to reactive oxygen species (ROS). Hyperoxia fails to increase mean ROS production, although minima are elevated above normoxic levels. Furthermore, a negative relationship between mean and mean ROS production indicates that higher ROS production is generally associated with lower . Our results, therefore, suggest a possible signalling role for ROS in DGC, rather than supporting the idea that DGC acts to reduce oxidative damage by regulating ROS production.

  7. Continuous and Discontinuous Modelling of Fracture in Concrete Using FEM

    CERN Document Server

    Tejchman, Jacek


    The book analyzes a quasi-static fracture process in concrete and reinforced concrete by means of constitutive models formulated within continuum mechanics. A continuous and discontinuous modelling approach was used. Using a continuous approach, numerical analyses were performed using a finite element method and three different enhanced continuum models: isotropic elasto-plastic, isotropic damage and anisotropic smeared crack one. The models were equipped with a characteristic length of micro-structure by means of a non-local and a second-gradient theory. So they could properly describe the formation of localized zones with a certain thickness and spacing and a related deterministic size effect. Using a discontinuous FE approach, numerical results of cracks using a cohesive crack model and XFEM were presented which were also properly regularized. Finite element analyses were performed with concrete elements under monotonic uniaxial compression, uniaxial tension, bending and shear-extension. Concrete beams un...

  8. Limit cycles for discontinuous generalized Lienard polynomial differential equations

    Directory of Open Access Journals (Sweden)

    Jaume Llibre


    Full Text Available We divide $\\mathbb{R}^2$ into sectors $S_1,\\dots ,S_l$, with $l>1$ even, and define a discontinuous differential system such that in each sector, we have a smooth generalized Lienard polynomial differential equation $\\ddot{x}+f_i(x\\dot{x} +g_i(x=0$, $i=1, 2$ alternatively, where $f_i$ and $g_i$ are polynomials of degree n-1 and m respectively. Then we apply the averaging theory for first-order discontinuous differential systems to show that for any $n$ and $m$ there are non-smooth Lienard polynomial equations having at least max{n,m} limit cycles. Note that this number is independent of the number of sectors.

  9. Mathematical properties of a discontinuous Cournot-Stackelberg model

    Energy Technology Data Exchange (ETDEWEB)

    Tramontana, Fabio, E-mail: [Universita degli Studi di Urbino, Department of Economics and Quantitative Methods, Via Saffi 42, 61029 Urbino (Italy); Gardini, Laura, E-mail: laura.gardini@uniurb.i [Universita degli Studi di Urbino, Department of Economics and Quantitative Methods, Via Saffi 42, 61029 Urbino (Italy); Puu, Toenu, E-mail: tonu.puu@econ.umu.s [CERUM, Umea University, SE-90187 Umea (Sweden)


    Research highlights: We analyze the global properties of a discontinuous two-dimensional map. We explain the occurring border collision bifurcations. We combine in a dynamic setting Cournot and Stackelberg duopoly models. - Abstract: The object of this work is to perform the global analysis of a recent duopoly model which couples the two points of view of Cournot and Stackelberg . The Cournot model is assumed with isoelastic demand function and unit costs. The coupling leads to discontinuous reaction functions, whose bifurcations, mainly border collision bifurcations, are investigated as well as the global structure of the basins of attraction. In particular, new properties are shown, associated with the introduction of horizontal branches, which differ significantly when the constant value is zero or positive and small. The good behavior of the model with positive constant is proved, leading to stable cycles of any period.

  10. A Streaming Language Implementation of the Discontinuous Galerkin Method (United States)

    Barth, Timothy; Knight, Timothy


    We present a Brook streaming language implementation of the 3-D discontinuous Galerkin method for compressible fluid flow on tetrahedral meshes. Efficient implementation of the discontinuous Galerkin method using the streaming model of computation introduces several algorithmic design challenges. Using a cycle-accurate simulator, performance characteristics have been obtained for the Stanford Merrimac stream processor. The current Merrimac design achieves 128 Gflops per chip and the desktop board is populated with 16 chips yielding a peak performance of 2 Teraflops. Total parts cost for the desktop board is less than $20K. Current cycle-accurate simulations for discretizations of the 3-D compressible flow equations yield approximately 40-50% of the peak performance of the Merrimac streaming processor chip. Ongoing work includes the assessment of the performance of the same algorithm on the 2 Teraflop desktop board with a target goal of achieving 1 Teraflop performance.

  11. Inverse Sturm-Liouville problem with discontinuity conditions

    Directory of Open Access Journals (Sweden)

    Mohammad Shahriari


    Full Text Available This paper deals with the boundary value problem involving the dierential equation ly := -y''+qy = λy, subject to the standard boundary conditions along with the following discontinuity conditions at a point a ε(0,π y(a + 0 = a1y(a - 0, y'(a + 0 = a1-1y'(a - 0 + a2y(a - 0, where q(x, a1,a2 are real, q ε L2(0,π and λ is a parameter independent of x. We develop the Hochestadt's result based on the transformation operator for inverse Sturm-Liouville problem when there are discontinuous conditions. Furthermore, we establish a formula for q(x - q~(x in the nite interval where q(x and q~(x are analogous functions.

  12. Application of Discontinuous PWM Modulation in Active Power Filters

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Asiminoaei, Lucian; Rodriguez, Pedro


    Classical discontinuous pulsewidth modulations (DPWMs) may not be efficiently applied in active power filters (APFs), because it is hard to predict the peak values of the inverter current, and consequently it is difficult to calculate the position of the clamped interval, that minimizes the switc......Classical discontinuous pulsewidth modulations (DPWMs) may not be efficiently applied in active power filters (APFs), because it is hard to predict the peak values of the inverter current, and consequently it is difficult to calculate the position of the clamped interval, that minimizes...... the switching losses in any operating point. This paper proposes a new DPWM strategy applied to shunt APFs. The proposed modulation strategy detects the current vector position relative to the inverter voltage reference and determines instantaneously the optimum clamped duration on each phase. It achieves...... on a three-phase voltage source inverter, rated at 7 kVA 400 V, controlled as an APF....

  13. Discontinuous Skeletal Gradient Discretisation methods on polytopal meshes (United States)

    Di Pietro, Daniele A.; Droniou, Jérôme; Manzini, Gianmarco


    In this work we develop arbitrary-order Discontinuous Skeletal Gradient Discretisations (DSGD) on general polytopal meshes. Discontinuous Skeletal refers to the fact that the globally coupled unknowns are broken polynomials on the mesh skeleton. The key ingredient is a high-order gradient reconstruction composed of two terms: (i) a consistent contribution obtained mimicking an integration by parts formula inside each element and (ii) a stabilising term for which sufficient design conditions are provided. An example of stabilisation that satisfies the design conditions is proposed based on a local lifting of high-order residuals on a Raviart-Thomas-Nédélec subspace. We prove that the novel DSGDs satisfy coercivity, consistency, limit-conformity, and compactness requirements that ensure convergence for a variety of elliptic and parabolic problems. Links with Hybrid High-Order, non-conforming Mimetic Finite Difference and non-conforming Virtual Element methods are also studied. Numerical examples complete the exposition.

  14. Forced-air warming discontinued: periprosthetic joint infection rates drop

    Directory of Open Access Journals (Sweden)

    Scott D. Augustine


    Full Text Available Several studies have shown that the waste heat from forced-air warming (FAW escapes near the floor and warms the contaminated air resident near the floor. The waste heat then forms into convection currents that rise up and contaminate the sterile field above the surgical table. It has been shown that a single airborne bacterium can cause a periprosthetic joint infection (PJI following joint replacement surgery. We retrospectively compared PJI rates during a period of FAW to a period of air-free conductive fabric electric warming (CFW at three hospitals. Surgical and antibiotic protocols were held constant. The pooled multicenter data showed a decreased PJI rate of 78% following the discontinuation of FAW and a switch to air-free CFW (n=2034; P=0.002. The 78% reduction in joint implant infections observed when FAW was discontinued suggests that there is a link between the waste FAW heat and PJIs.

  15. Finite element and discontinuous Galerkin methods for transient wave equations

    CERN Document Server

    Cohen, Gary


    This monograph presents numerical methods for solving transient wave equations (i.e. in time domain). More precisely, it provides an overview of continuous and discontinuous finite element methods for these equations, including their implementation in physical models, an extensive description of 2D and 3D elements with different shapes, such as prisms or pyramids, an analysis of the accuracy of the methods and the study of the Maxwell’s system and the important problem of its spurious free approximations. After recalling the classical models, i.e. acoustics, linear elastodynamics and electromagnetism and their variational formulations, the authors present a wide variety of finite elements of different shapes useful for the numerical resolution of wave equations. Then, they focus on the construction of efficient continuous and discontinuous Galerkin methods and study their accuracy by plane wave techniques and a priori error estimates. A chapter is devoted to the Maxwell’s system and the important problem ...

  16. First Episode Mania Probably Associated with Discontinuation of Paroxetine Treatment

    Directory of Open Access Journals (Sweden)

    Birmay Cam


    Full Text Available Antidepressant-induced mania have been reported with all major antidepressant classes in a subgroup of about 20-40% of bipolar patients. Mania/hypomania due to antidepressant withdrawal is rarely reported in the literature as case report. Mania/hypomania due to antidepressant withdrawal is reported to be associated with tricyclic antidepressants as well as selective serotonin reuptake inhibitors. This article offered mania occurring after discontinuation of treatment with paroxetine male patient. Mania associated with antidepressant discontinuation of the differential diagnosis, possible mechanisms, the treatment has been discussed in the literature. Clinicians should be cautious mania/hypomania associated with antidepressant withdrawal. To do follow-up studies and case reports will help to clarify this table. [Cukurova Med J 2015; 40(Suppl 1: 12-17

  17. Consequences of a benzodiazepine discontinuation programme in family practice on psychotropic medication prescription to the participants.

    NARCIS (Netherlands)

    Gorgels, W.J.M.J.; Oude Voshaar, R.C.; Mol, A.J.J.; Lisdonk, E.H. van de; Mulder, J.; Hoogen, H.J.M. van den; Balkom, A.J.L.M. van; Breteler, M.H.M.; Zitman, F.G.


    BACKGROUND: Whether long-term benzodiazepine users who participate in a family practice-based benzodiazepine discontinuation programme substitute benzodiazepines by other psychotropics is not clear. OBJECTIVE: To evaluate the impact of a benzodiazepine discontinuation programme on non-benzodiazepine

  18. Extended displacement discontinuity method for analysis of cracks in 2D thermal piezoelectric semiconductors (United States)

    Zhao, MingHao; Pan, YiBo; Fan, CuiYing; Xu, GuangTao


    The extended displacement discontinuities method has previously been used for crack analysis of elastic materials, piezoelectric media, magneto-electro-elastic media and piezoelectric semiconductors. Here, this method is extended to study cracks in two-dimensional n-type thermal piezoelectric semiconductors. The extended displacement discontinuities include the conventional displacement discontinuity, electric potential discontinuity, carrier density discontinuity, as well as temperature discontinuity across crack faces; correspondingly, the extended stresses represent conventional stress, electric displacement, electric current, and heat flux. Employing a Fourier transform, the fundamental solutions for a line crack under uniformly distributed extended displacement discontinuities on the crack faces are derived under mechanical, electrical, and heat loading. Based on the obtained fundamental solutions, an extended displacement discontinuity boundary element method is developed. The stress and heat flux intensity factors at the crack tip are calculated under different combined loadings.

  19. Regression Discontinuity Design: Simulation and Application in Two Cardiovascular Trials with Continuous Outcomes

    NARCIS (Netherlands)

    van Leeuwen, Nikki; Lingsma, Hester F.; de Craen, Anton J. M.; Nieboer, Daan; Mooijaart, Simon P.; Richard, Edo; Steyerberg, Ewout W.


    In epidemiology, the regression discontinuity design has received increasing attention recently and might be an alternative to randomized controlled trials (RCTs) to evaluate treatment effects. In regression discontinuity, treatment is assigned above a certain threshold of an assignment variable for

  20. 76 FR 43898 - Post Office Organization and Administration: Establishment, Classification, and Discontinuance... (United States)


    ... 241 Post Office Organization and Administration: Establishment, Classification, and Discontinuance... 241--RETAIL ORGANIZATION AND ADMINISTRATION: ESTABLISHMENT, CLASSIFICATION, AND DISCONTINUANCE 0 1... Service published an amendment to the rules concerning the establishment, classification, and...

  1. 76 FR 66184 - Post Office Organization and Administration: Establishment, Classification, and Discontinuance (United States)


    ... 241 Post Office Organization and Administration: Establishment, Classification, and Discontinuance... ORGANIZATION AND ADMINISTRATION: ESTABLISHMENT, CLASSIFICATION, AND DISCONTINUANCE 0 1. The authority citation... (``Commission'' or ``PRC''), five state legislators, three postmasters' and postal supervisors' organizations...


    Directory of Open Access Journals (Sweden)

    Biljana kovačević-Zelić


    Full Text Available The paper deals with the problem of discontinuous ruck material modelling within the framework of theory of plasticity. The applicability of two models, i.e. Mohr-Coulomb's ideal plasticity and plastic anisotropy (ubiquitous joint model, is examined. Numerical analyses were performed with FLAC - finite difference code. The comparision of above mentioned constitutive models is made through the demonstrated mechanical behaviour in the direct shear test (the paper is published in Croatian.

  3. Multigrid method for elliptic equations with anisotropic discontinuous coefficients (United States)

    Zhukov, V. T.; Novikova, N. D.; Feodoritova, O. B.


    For difference elliptic equations, an algorithm based on Fedorenko's multigrid method is constructed. The algorithm is intended for solving three-dimensional boundary value problems for equations with anisotropic discontinuous coefficients on parallel computers. Numerical results confirming the performance and parallel efficiency of the multigrid algorithm are presented. These qualities are ensured by using, as a multigrid triad, the standard Chebyshev iteration for coarsest grid equations, Chebyshev-type smoothing explicit iterative procedures, and intergrid transfer operators in problem-dependent form.

  4. Stability Analysis of Discontinuous Galerkin Approximations to the Elastodynamics Problem

    KAUST Repository

    Antonietti, Paola F.


    We consider semi-discrete discontinuous Galerkin approximations of both displacement and displacement-stress formulations of the elastodynamics problem. We prove the stability analysis in the natural energy norm and derive optimal a-priori error estimates. For the displacement-stress formulation, schemes preserving the total energy of the system are introduced and discussed. We verify our theoretical estimates on two and three dimensions test problems.

  5. Adaptive discontinuous Galerkin methods for nonlinear parabolic problems


    Metcalfe, Stephen Arthur


    This work is devoted to the study of a posteriori error estimation and adaptivity in parabolic problems with a particular focus on spatial discontinuous Galerkin (dG) discretisations. We begin by deriving an a posteriori error estimator for a linear non-stationary convection-diffusion problem that is discretised with a backward Euler dG method. An adaptive algorithm is then proposed to utilise the error estimator. The effectiveness of both the error estimator and the proposed algorithm is sho...

  6. Discontinuous Galerkin Finite Element Method for Parabolic Problems (United States)

    Kaneko, Hideaki; Bey, Kim S.; Hou, Gene J. W.


    In this paper, we develop a time and its corresponding spatial discretization scheme, based upon the assumption of a certain weak singularity of parallel ut(t) parallel Lz(omega) = parallel ut parallel2, for the discontinuous Galerkin finite element method for one-dimensional parabolic problems. Optimal convergence rates in both time and spatial variables are obtained. A discussion of automatic time-step control method is also included.

  7. GH administration and discontinuation in healthy elderly men

    DEFF Research Database (Denmark)

    Lange, K H; Isaksson, F; Rasmussen, M H


    GH administration results in increased lean body mass (LBM), decreased fat mass (FM) and increased energy expenditure (EE). GH therapy may therefore have potential benefits, especially in the elderly, who are known to have decreased function of the GH/IGF-I axis. Several studies have focused on e...... discontinuation on body composition, resting oxygen uptake (VO2), resting heart rate (HR) and GH related serum markers in healthy elderly men....

  8. State and data techniques for control of discontinuous systems

    Energy Technology Data Exchange (ETDEWEB)

    Kisner, R.A.


    This paper describes a technique for structured analysis and design of automated control systems. The technique integrates control of continuous and discontinuous nuclear power plant subsystems and components. A hierarchical control system with distributed intelligence follows from applying the technique. Further, it can be applied to all phases of control system design. For simplicity, the example used in the paper is limited to phase 1 design (basic automatic control action), in which no maintenance, testing, or contingency capability is attempted. 11 figs.

  9. Energy landscapes for machine learning (United States)

    Ballard, Andrew J.; Das, Ritankar; Martiniani, Stefano; Mehta, Dhagash; Sagun, Levent; Stevenson, Jacob D.; Wales, David J.

    Machine learning techniques are being increasingly used as flexible non-linear fitting and prediction tools in the physical sciences. Fitting functions that exhibit multiple solutions as local minima can be analysed in terms of the corresponding machine learning landscape. Methods to explore and visualise molecular potential energy landscapes can be applied to these machine learning landscapes to gain new insight into the solution space involved in training and the nature of the corresponding predictions. In particular, we can define quantities analogous to molecular structure, thermodynamics, and kinetics, and relate these emergent properties to the structure of the underlying landscape. This Perspective aims to describe these analogies with examples from recent applications, and suggest avenues for new interdisciplinary research.

  10. Greenhouse warming and landscape care (United States)

    Kevin T. Smith


    Climate change is one of the few truly planetary processes that influence the assessments and actions of governments and of everyday citizens. Principles and practices of ecological landscaping fit well with concern about hte effects of climate change.

  11. Magical Landscapes and Designed Cities

    DEFF Research Database (Denmark)

    Raahauge, Kirsten Marie


    from the point of view of the city, where order, design, planning and commerce are important cityscape qualities. The article deals with the way in which these two parts of the city, landscape and brandscape are complementary parts of the city-web. Analytical points made by Mauss, Lévi......Abstract  Based on anthropological fieldwork conducted in Skåde Bakker and Fedet, two well-off neighbourhoods in the outskirts of Århus, Denmark, this article focusses on how landscapes are perceived. Local residents describe and use the landscapes of Skåde Bakker and Fedet as endowed...... with “something special,” a feel-good, (almost spiritual) healing power (just moments away from the bustling city). In Melanesia, such a spiritual force goes by the name of “mana”. Århus’ mana landscapes are only invested with this huge, floating quality because they are near the city. Furthermore, they are seen...

  12. Qualified Health Plan (QHP) Landscape (United States)

    U.S. Department of Health & Human Services — QHP Landscape Files present basic information about certified Qualified Health Plans and Stand-alone Dental Plans for individuals-families and small businesses...

  13. Landscape Studies in the University (United States)

    Park, Richard


    The form and structure of cultural space--the landscape--is in a constant process of change. The designer must understand the symbolic content and the cultural forces that compose the process of structural evolution. (Author/LBH)

  14. GDOT historic landscape mitigation evaluation. (United States)


    Historic Landscapes are our nations finger prints of the past. They provide us a glimpse into the way people worked, lived, and admired : the land. As the earths population continues to grow, so does the need for infrastructure improvements suc...

  15. Flowscapes : Designing infrastructure as landscape

    NARCIS (Netherlands)

    Nijhuis, S.; Jauslin, D.T.; Van der Hoeven, F.D.


    Social, cultural and technological developments of our society are demanding a fundamental review of the planning and design of its landscapes and infrastructures, in particular in relation to environmental issues and sustainability. Transportation, green and water infrastructures are important

  16. The farmer as a landscape steward

    DEFF Research Database (Denmark)

    Raymond, Christopher M.; Bieling, Claudia; Fagerholm, Nora


    We develop a landscape stewardship classification which distinguishes between farmers’ understanding of landscape stewardship, their landscape values, and land management actions. Forty semi-structured interviews were conducted with small-holder (... production assets; (3) a holistic frame focusing on farmers’ role as a conservationist, primary producer, and manager of a range of landscape values, and; (4) an instrumental frame focusing on the financial benefits associated with compliance with agri-environmental schemes. We compare the landscape values...... and land management actions that emerged across stewardship types, and discuss the global implications of the landscape stewardship classification for the engagement of farmers in landscape management....

  17. Simulating historical landscape dynamics using the landscape fire succession model LANDSUM version 4.0 (United States)

    Robert E. Keane; Lisa M. Holsinger; Sarah D. Pratt


    The range and variation of historical landscape dynamics could provide a useful reference for designing fuel treatments on today's landscapes. Simulation modeling is a vehicle that can be used to estimate the range of conditions experienced on historical landscapes. A landscape fire succession model called LANDSUMv4 (LANDscape SUccession Model version 4.0) is...

  18. Why do couples discontinue unlimited free IVF treatments? (United States)

    Lande, Yechezkel; Seidman, Daniel S; Maman, Ettie; Baum, Micha; Hourvitz, Ariel


    Worldwide, IVF is often discontinued before a live birth is achieved due to high costs. Even when partial financial coverage is provided, often medical providers advise treatment discontinuation. In Israel, unlimited IVF is offered free of charge for a couples' first two children. Our objective was to assess the reasons couples discontinue IVF treatments before achieving two children in a completely unlimited cost-free environment. This cohort study included all primary infertile women, IVF cycle to Sheba IVF unit between 2001 and 2002. Patients were followed until February 2012. Those who ceased treatments for 12 months were interviewed to assess the main reason they ceased treatments. Of the 134 couples included, only 46 ceased IVF treatments without achieving two children, after performing an average of 6.2 IVF cycles to achieve their first birth. The reasons given were: lost hope of success (13), psychological burden (18), divorce (6), medical staff recommendation (5), bureaucratic difficulties (3) and general medical condition (1). The main reasons for "drop out" in our cost-free environment were as follows: psychological burden and lost hope of success. Due to high availability of treatments, medical staff recommendation was a less significant factor in our study.

  19. Pregabalin in the discontinuation of long-term benzodiazepines' use. (United States)

    Oulis, Panagiotis; Konstantakopoulos, George; Kouzoupis, Anastasios V; Masdrakis, Vasilios G; Karakatsanis, Nikolaos A; Karapoulios, Evangelos; Kontoangelos, Konstantinos A; Papadimitriou, George N


    Tolerance, dependence, and adverse effects on cognitive functions are well-known consequences of long-term use of benzodiazepines (BDZ), especially at high doses, raising thorny therapeutic problems in their discontinuation. One promising pharmacological agent in BDZ discontinuation might be the newer anti-epileptic pregabalin, already successfully tested in the treatment of anxiety disorders. We report on a sample of 15 patients with long-term, mostly high-dose dependence from BDZ, treated with pregabalin in an open-label study at doses 225-900 mg. All patients discontinued successfully BDZ in 3-14 weeks, moreover with a significant reduction of their previous anxiety levels under BDZ. In addition, patients showed also a significant amelioration in their cognitive functioning. Pregabalin's side-effects were mild and transient, lasting only during the first 2 weeks of treatment. Although preliminary, our findings suggest that pregabalin may be one new promising agent in the treatment of BDZ dependence. (c) 2008 John Wiley & Sons, Ltd.

  20. Discontinued students in nursing education - Who and why? (United States)

    Kukkonen, Pia; Suhonen, Riitta; Salminen, Leena


    There has been increasing interest in student nurse attrition due to the high level of attrition rates in many countries. Studies about nursing education and attrition have been conducted internationally, but only a few have explored attrition from the perspective of the students' own experiences. The purpose of this study was to describe who is a discontinued student in nursing education and the students' own experiences of reasons for leaving a nursing school. A descriptive design and qualitative approach was used. 25 nursing students were interviewed at two different universities of applied sciences in Finland. Four different types of discontinued nursing students were identified: those who moved to another school, those who faced a life crisis, those who made the wrong career choice and those who lived 'busy years'. The results show that the nursing student population is diverse, which has an effect on the students' career intentions, their learning and their ability to cope with studies. In nursing education, it is important to identify students who are at risk of discontinue their studies and develop individual support systems to help nursing students complete their studies and enter into the workforce. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Improvement of discontinuity factor for strong absorber region

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Jiong, E-mail:; Li, Fu, E-mail:; Zhang, Han; Zhou, Xiafeng; Fan, Kai; Wang, Lidong; Lu, Jianan


    At Institute of Nuclear and New Energy Technology (INET) the discontinuity factor corrected diffusion method with the homogenization technology was developed and applied in the control rod worth calculation of the pebble bed high temperature gas cooled reactor. But the result with the normal procedure is not accurate enough for a strong absorber. The numerical analysis shows that the strong absorber still has great influence on the flux distribution in the nearby graphite region, so that the flux distribution obtained by the normal diffusion method does not agree with the transport result. Thus, two improvements were proposed in this paper. First, instead of the neutron flux in the middle of the fine mesh, the surface flux of the absorber region was calculated through the net current in the boundary of the region; and then, while the discontinuity factor of the homogenized absorber region should be calculated, the discontinuity factor of the neighboring graphite region on the other side of the interface should also be calculated to eliminate the influence of the strong absorber. The numerical results demonstrate that, based on the improved method, the accuracy of heterogeneous transport calculation can be achieved by a diffusion calculation.

  2. Priapism Followed by Discontinuation of Methadone: A rare Case Report

    Directory of Open Access Journals (Sweden)

    Seyed-Ali Mostafavi


    Full Text Available Objective: Priapism is defined by persistent, painful penile erection which occurs without sexual stimulation. Methadone is used as an analgesic and is also used in detoxification and maintenance protocol for opioid dependence treatment. Here we will report a case of a male with priapism after rapid discontinuation doses of methadone.Case presentation: The case was a young married male who referred to a psychiatry clinic due to long-time spontaneous erections. The patient had no history of mental disorders, trauma or sickle cell anemia. He used to smoke opium for five years and used methadone for four years at a dose of 17 cc daily, which he abruptly discontinued. Then he often experienced spontaneous and painful erections without physical or mental stimulation that caused him shame and embarrassment .Conclusion: In this case, chronology indicates that rapid discontinuation of methadone was possibly responsible for the occurrence of priapism. This may have happened due to a compensatory reaction to methadone side effect of erectile dysfunction, followed by its rapid withdrawal.

  3. Effects of discontinuities of the derivatives of the inflaton potential

    Energy Technology Data Exchange (ETDEWEB)

    Gallego Cadavid, Alexander [Universidad de Antioquia, Instituto de Fisica, Medellin (Colombia); Kyoto University, Yukawa Institute for Theoretical Physics, Kyoto (Japan); Enea Romano, Antonio [Universidad de Antioquia, Instituto de Fisica, Medellin (Colombia); Kyoto University, Yukawa Institute for Theoretical Physics, Kyoto (Japan); University of Crete, Department of Physics, Heraklion (Greece)


    We study the effects of a class of features of the inflaton potential, corresponding to discontinuities in its derivatives. We perform fully numerical calculations and derive analytical approximations for the curvature perturbations spectrum and the bispectrum which are in good agreement with the numerical results. The spectrum of primordial perturbations has oscillations around the scale k{sub 0} which leaves the horizon at the time τ{sub 0} when the feature occurs, with the amplitude and phase of the oscillations determined by the size and the order of the discontinuity. The large scale bispectrum in the squeezed and equilateral limits have a very similar form and are linearly suppressed. Both in the squeezed and the equilateral small scale limit the bispectrum has an oscillatory behavior whose phase depends on the parameters determining the discontinuity, and whose amplitude is inversely proportional to the scale. Given the generality of this class of features they could be used to model or classify phenomenologically different types of non-Gaussian features encountered in observational data such as the cosmic microwave background radiation or large scale structure. (orig.)

  4. Effects of discontinuities of the derivatives of the inflaton potential

    Energy Technology Data Exchange (ETDEWEB)

    Cadavid, Alexander Gallego [Instituto de Fisica, Universidad de Antioquia, A.A.1226, Medellin (Colombia); Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto (Japan); Romano, Antonio Enea, E-mail: [Instituto de Fisica, Universidad de Antioquia, A.A.1226, Medellin (Colombia); Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto (Japan); Department of Physics, University of Crete, 71003, Heraklion (Greece)


    We study the effects of a class of features of the inflaton potential, corresponding to discontinuities in its derivatives. We perform fully numerical calculations and derive analytical approximations for the curvature perturbations spectrum and the bispectrum which are in good agreement with the numerical results. The spectrum of primordial perturbations has oscillations around the scale k{sub 0} which leaves the horizon at the time τ{sub 0} when the feature occurs, with the amplitude and phase of the oscillations determined by the size and the order of the discontinuity. The large scale bispectrum in the squeezed and equilateral limits have a very similar form and are linearly suppressed. Both in the squeezed and the equilateral small scale limit the bispectrum has an oscillatory behavior whose phase depends on the parameters determining the discontinuity, and whose amplitude is inversely proportional to the scale. Given the generality of this class of features they could be used to model or classify phenomenologically different types of non-Gaussian features encountered in observational data such as the cosmic microwave background radiation or large scale structure.

  5. Dynamics in a discontinuous field: The smooth Fermi piston. (United States)

    Worrell, G. A.; Matulich, A.; Miller, B. N.


    In this paper we examine a version of the Fermi piston with a discontinuous, but nonimpulsive, periodic driving force. The dynamics of a particle moving in one spatial dimension are studied using a combination of numerical and analytical techniques. The configuration space of the particle is divided into two regions of constant acceleration that are of equal magnitude and opposite direction. The point of discontinuity F(t) dividing the regions changes periodically in time. The method of surface-of-section is used to study the phase space (phi(n), v(n)), where phi(n) is the phase of the driving function and v(n) is the velocity of the particle at the nth encounter between the particle and boundary. We show that it is not possible to stochastically drive up the energy indefinitely except for the cases where F is discontinuous, or dF/dt is not finite everywhere. In addition, we find a new mechanism, other than KAM tori, for segmenting the phase space. As in the KAM picture, the central cause of the new behavior is resonance between the natural period of the particle and the period of the driving force. The boundaries to diffusion for continuous driving functions result from parabolic fixed points that span the entire phase range.

  6. When is it safe to discontinue AED treatment? (United States)

    Camfield, Peter; Camfield, Carol


    When people with epilepsy become seizure-free with daily antiepileptic drug (AED) management, there is a very individual decision to be made about discontinuing this treatment. After 1-6 years of seizure-freedom, it is estimated that 69% of children and 61% of adults remain seizure-free when AEDs are tapered and stopped. The length of time that a patient is seizure-free does not influence the success rate in children but may in adults. The epilepsy syndrome does not seem to influence the chance of success in 75% of children; however, several prediction schemes based on risk factors for recurrence may be useful. There are two major risks in discontinuing treatment--a tiny risk that the epilepsy will not be controlled again and a tiny risk of death during a recurrence. Children who have had 1-2 years seizure-free deserve a chance to discontinue their AED treatment, whereas in adults this decision probably should wait until there have been at least 4 years of seizure-freedom.

  7. Phase discontinuity predictions using a machine-learning trained kernel. (United States)

    Sawaf, Firas; Groves, Roger M


    Phase unwrapping is one of the key steps of interferogram analysis, and its accuracy relies primarily on the correct identification of phase discontinuities. This can be especially challenging for inherently noisy phase fields, such as those produced through shearography and other speckle-based interferometry techniques. We showed in a recent work how a relatively small 10×10 pixel kernel was trained, through machine learning methods, for predicting the locations of phase discontinuities within noisy wrapped phase maps. We describe here how this kernel can be applied in a sliding-window fashion, such that each pixel undergoes 100 phase-discontinuity examinations--one test for each of its possible positions relative to its neighbors within the kernel's extent. We explore how the resulting predictions can be accumulated, and aggregated through a voting system, and demonstrate that the reliability of this method outperforms processing the image by segmenting it into more conventional 10×10 nonoverlapping tiles. When used in this way, we demonstrate that our 10×10 pixel kernel is large enough for effective processing of full-field interferograms. Avoiding, thus, the need for substantially more formidable computational resources which otherwise would have been necessary for training a kernel of a significantly larger size.

  8. Saddleworth, Responding to a Landscape


    Murray, Matthew


    Matthew Murray's Landscape publication Saddleworth, Responding To A Landscape. Forward by Martin Barnes Senior Curator of Photographs at The Victoria and Albert Museum, London, Artist Richard Billingham and Maartje van den Heuvel Curator Photography and Media Culture -Leiden Institute. \\ud \\ud ‘Every trip I have taken to Saddleworth Moor over four years has encapsulated each season, weather and cloud pattern, rain, sunshine, snow, early morning clear skies and the sense of the bitter cold of ...

  9. Landscapes of the Digital Baroque. (United States)

    Singh, Gary


    Alvaro Ocampo traversed many landscapes to arrive at his current space in the digital art landscape. Eventually, the artist then made his way to the digital world, where he is no longer subjected to the tyranny of the one-off. He believes digital art is the new version of traditional etching in the way that it eliminates the idea of the one original piece of art.

  10. The landscapes of tourism space


    Włodarczyk, Bogdan


    The author attempts to define the term ‘tourism landscape’. It is treated as an important attribute of tourism space therefore, apart from its definition, the author presents its characteristic features and various types of such spaces with differing tourism landscapes. The landscapes of tourism space are treated not only as tourism assets or attractions, but also as the consequences of tourism activity on the natural and cultural environment.

  11. Nanofiber patent landscape. (United States)

    Ngiam, Michelle; Ramakrishna, Seeram; Raghunath, Michael; Chan, Casey K


    Despite the large number of publications in peer review literature in the field of nanofibers, there is still uncertainty as to what aspects of these research results have commercial applications. In an effort to better understand the technological progress made in the field of nanofibers, we surveyed the patents issued in the United States from 1976 up to end 2006. The present review will provide an overall view of the current patent landscape including trends and key applications. Key assignees and key inventors were identified and their contributions were discussed. Patents were identified using keywords such as nanofibers, ultrafine, and electrospinning. After patents were downloaded, we reviewed each patent for relevancy and identified 100 patents to be related to nanofibers. 75% of the current issued patents on nanofibers are directed at either fabrication methods or the use of nanofibers in filtration systems. The patent data indicates that medical applications and medical products using nanofibers appear to be the emerging application for nanofibers. We anticipate a growing number of patents on novel applications for nanofiber would originate from academic centers in the future.


    Energy Technology Data Exchange (ETDEWEB)

    CHERTKOV, MICHAEL [Los Alamos National Laboratory; STEPANOV, MIKHAIL [Los Alamos National Laboratory


    The authors discuss performance of Low-Density-Parity-Check (LDPC) codes decoded by Linear Programming (LP) decoding at moderate and large Signal-to-Noise-Ratios (SNR). Frame-Error-Rate (FER) dependence on SNR and the noise space landscape of the coding/decoding scheme are analyzed by a combination of the previously introduced instanton/pseudo-codeword-search method and a new 'dendro' trick. To reduce complexity of the LP decoding for a code with high-degree checks, {ge} 5, they introduce its dendro-LDPC counterpart, that is the code performing identifically to the original one under Maximum-A-Posteriori (MAP) decoding but having reduced (down to three) check connectivity degree. Analyzing number of popular LDPC codes and their dendro versions performing over the Additive-White-Gaussian-Noise (AWGN) channel, they observed two qualitatively different regimes: (i) error-floor sets early, at relatively low SNR, and (ii) FER decays with SNR increase faster at moderate SNR than at the largest SNR. They explain these regimes in terms of the pseudo-codeword spectra of the codes.

  13. Landscapes and molecular evolution (United States)

    Schuster, Peter


    Evolution of RNA molecules in vitro is visualized as a hill-climbing process on a fitness landscape that can be derived from molecular properties and functions. The optimization process is shaped by a high degree of redundance in sequence-to-structure mappings: there are many more sequences than structures and sequences folding into the same structure are (almost) randomly distributed in sequence space. Two consequences of this redundance are important for evolution: shape space covering by small connected regions in sequence space and the existence of extended neutral networks. Both results together explain how nature can fast and efficiently find solutions to complex optimization problems by trial and error while the number of possible genotypes exceeds all imagination. In the presence of neutral networks populations avoid being caught in evolutionary traps and eventually reach the global optimum through a composite dynamics of adaptive walks and random drift. Results derived from mathematical analysis are confronted with the results of computer simulation and available experimental data.

  14. Titan Polar Landscape Evolution (United States)

    Moore, Jeffrey M.


    With the ongoing Cassini-era observations and studies of Titan it is clear that the intensity and distribution of surface processes (particularly fluvial erosion by methane and Aeolian transport) has changed through time. Currently however, alternate hypotheses substantially differ among specific scenarios with respect to the effects of atmospheric evolution, seasonal changes, and endogenic processes. We have studied the evolution of Titan's polar region through a combination of analysis of imaging, elevation data, and geomorphic mapping, spatially explicit simulations of landform evolution, and quantitative comparison of the simulated landscapes with corresponding Titan morphology. We have quantitatively evaluated alternate scenarios for the landform evolution of Titan's polar terrain. The investigations have been guided by recent geomorphic mapping and topographic characterization of the polar regions that are used to frame hypotheses of process interactions, which have been evaluated using simulation modeling. Topographic information about Titan's polar region is be based on SAR-Topography and altimetry archived on PDS, SAR-based stereo radar-grammetry, radar-sounding lake depth measurements, and superposition relationships between geomorphologic map units, which we will use to create a generalized topographic map.

  15. 41 CFR 109-39.105 - Discontinuance or curtailment of service. (United States)


    ... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 109-39.105 Discontinuance or... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Discontinuance or...

  16. Numerical Simulations of Shock Wave Refraction at Inclined Gas Contact Discontinuity (United States)

    Bulat, Pavel V.; Volkov, Konstantin N.


    When a shock wave interacts with a contact discontinuity, there may appear a reflected rarefaction wave, a deflected contact discontinuity and a refracted supersonic shock. The numerical simulation of shock wave refraction at a plane contact discontinuity separating gases with different densities is performed. Euler equations describing inviscid…

  17. Predictors of discontinuation of benzodiazepine prescription after sending a letter to long-term benzodiazepine users in family practice.

    NARCIS (Netherlands)

    Gorgels, W.J.M.J.; Oude Voshaar, R.C.; Mol, A.J.J.; Lisdonk, E.H. van de; Balkom, A.J.L.M. van; Breteler, M.H.M.; Hoogen, H.J.M. van den; Mulder, J.; Zitman, F.G.


    BACKGROUND: Predictors of benzodiazepine discontinuation after sending a discontinuation letter by the family practitioner have not been established sufficiently. OBJECTIVE: To identify predictors of short- and long-term discontinuation of benzodiazepine use and relapse in use after a minimal

  18. The shifting beverage landscape. (United States)

    Storey, Maureen


    STOREY, M.L. The shifting beverage landscape. PHYSIOL BEHAV, 2010. - Simultaneous lifestyle changes have occurred in the last few decades, creating an imbalance in energy intake and energy expenditure that has led to overweight and obesity. Trends in the food supply show that total daily calories available per capita increased 28% since 1970. Total energy intake among men and women has also increased dramatically since that time. Some have suggested that intake of beverages has had a disproportional impact on obesity. Data collected by the Beverage Marketing Corporation between 1988-2008 demonstrate that, in reality, fewer calories per ounce are being produced by the beverage industry. Moreover, data from the National Cancer Institute show that soft drink intake represents 5.5% of daily calories. Data from NHANES 1999-2003 vs. 2003-06 may demonstrate a shift in beverage consumption for age/gender groups, ages 6 to>60years. The beverages provided in schools have significantly changed since 2006 when the beverage industry implemented School Beverage Guidelines. This voluntary action has removed full-calorie soft drinks from participating schools across the country. This shift to lower-calorie and smaller-portion beverages in school has led to a significant decrease in total beverage calories in schools. These data support the concept that to prevent and treat obesity, public health efforts should focus on energy balance and that a narrow focus on sweetened beverages is unlikely to have any meaningful impact on this complex problem. Copyright 2010 Elsevier Inc. All rights reserved.

  19. The Effect of Melatonin on Benzodiazepine Discontinuation and Sleep Quality in Adults Attempting to Discontinue Benzodiazepines: A Systematic Review and Meta-Analysis. (United States)

    Wright, Angela; Diebold, Jacqueline; Otal, Jaskiran; Stoneman, Carly; Wong, Jonathan; Wallace, Christine; Duffett, Mark


    Abrupt discontinuation of benzodiazepines often results in side effects including anxiety and insomnia, which can be barriers to discontinuation among long-term users. Melatonin improves the onset, duration, and quality of sleep. By preventing insomnia in those attempting to discontinue benzodiazepines, melatonin may facilitate benzodiazepine discontinuation. The primary objective was to determine the effect of melatonin compared with placebo on benzodiazepine discontinuation in adults attempting to discontinue benzodiazepines. The secondary objective was to determine the effect of melatonin on sleep quality in this population. We searched PubMed, MEDLINE, EMBASE, PsychINFO, and from inception to November 2014. We included randomized controlled trials published in English comparing melatonin with placebo that reported benzodiazepine discontinuation or sleep quality. Two reviewers independently screened trials, extracted data, and assessed the risk of bias. We included six trials randomizing 322 participants. The mean age of participants was approximately 64 years. The trials used varied tapering strategies to discontinue benzodiazepines over 4-10 weeks while using melatonin. Melatonin had no effect on the odds of successfully discontinuing benzodiazepines (odds ratio 0.72, 95% confidence interval 0.21-2.41, p = 0.59). There was important heterogeneity among the trials (I (2) = 76%). The effect of melatonin on sleep quality was inconsistent. Melatonin had no effect on benzodiazepine discontinuation while the effect of melatonin on sleep quality was inconsistent. We cannot rule out a role of melatonin in improving benzodiazepine discontinuation or sleep quality owing to imprecise effect estimates. Larger, well-designed, and reported randomized controlled trials may provide more valid and precise estimates of the effect of melatonin on these outcomes.

  20. Persistent sexual dysfunction after discontinuation of selective serotonin reuptake inhibitors. (United States)

    Csoka, Antonei B; Csoka, A; Bahrick, Audrey; Mehtonen, Olli-Pekka


    Sexual dysfunctions such as low libido, anorgasmia, genital anesthesia, and erectile dysfunction are very common in patients taking selective serotonin reuptake inhibitors (SSRIs). It has been assumed that these side effects always resolve after discontinuing treatment, but recently, four cases were presented in which sexual function did not return to baseline. Here, we describe three more cases. Case #1: A 29-year-old with apparently permanent erectile dysfunction after taking fluoxetine 20 mg once daily for a 4-month period in 1996. Case #2: A 44-year-old male with persistent loss of libido, genital anesthesia, ejaculatory anhedonia, and erectile dysfunction after taking 20-mg once daily citalopram for 18 months. Case #3: A 28-year-old male with persistent loss of libido, genital anesthesia, and ejaculatory anhedonia since taking several different SSRIs over a 2-year period from 2003-2005. No psychological issues related to sexuality were found in any of the three cases, and all common causes of sexual dysfunction such as decreased testosterone, increased prolactin or diabetes were ruled out. Erectile capacity is temporarily restored for Case #1 with injectable alprostadil, and for Case #2 with oral sildenafil, but their other symptoms remain. Case #3 has had some reversal of symptoms with extended-release methylphenidate, although it is not yet known if these prosexual effects will persist when the drug is discontinued. SSRIs can cause long-term effects on all aspects of the sexual response cycle that may persist after they are discontinued. Mechanistic hypotheses including persistent endocrine and epigenetic gene expression alterations were briefly discussed.

  1. Integrating Landscape Ecology into Natural Resource Management (United States)

    Liu, Jianguo; Taylor, William W.


    To achieve sustainable resource management, it is essential to obtain insightful guidance from emerging disciplines such as landscape ecology. This text addresses the links between landscape ecology and natural resource management, discussing these links in the context of various landscape types, diverse sets of resources, and broad ranges of management issues. A large number of landscape ecology concepts, principles, and methods are introduced. Critical reviews of past management practices and a number of case studies are presented. The text provides many guidelines for managing natural resources from a landscape perspective and offers useful suggestions for landscape ecologists to carry out research relevant to natural resource management.

  2. Level set method for solving Poisson's equation with discontinuous nonlinearities

    Directory of Open Access Journals (Sweden)

    Joseph Kolibal


    Full Text Available We study semi-linear elliptic free boundary problems in which the forcing term is discontinuous; i.e., a Poisson's equation where the forcing term is the Heaviside function applied to the unknown minus a constant. This approach uses level sets to construct a monotonic sequence of iterates which converge to a class of solutions to the free boundary problem. The monotonicity of the construction based on nested sets provides insight into the connectivity of the free boundary sets associated with the solutions.

  3. A Discontinuous Galerkin Model for Fluorescence Loss in Photobleaching

    DEFF Research Database (Denmark)

    Hansen, Christian Valdemar; Schroll, Achim; Wüstner, Daniel


    Fluorescence loss in photobleaching (FLIP) is a modern microscopy method for visualization of transport processes in living cells. This paper presents the simulation of FLIP sequences based on a calibrated reaction–di usion system de ned on segmented cell images. By the use of a discontinuous...... of the nuclear membrane for GFP passage, directly from the FLIP image series. Thus, we present for the rst time, to our knowledge, a quantitative computational FLIP method for inferring several molecular transport parameters in parallel from FLIP image data acquired at commercial microscope systems....

  4. [Reversible catatonia after the abrupt discontinuation of clozapine: Case report]. (United States)

    Jaafari, M; Bout, A; Rammouz, I; Aalouane, R


    In this paper, we report the case of a patient, aged 26, with schizophrenia who was admitted to psychiatric emergencies for catatonia, one week after abrupt discontinuation of clozapine. An improvement was seen after only two days of the reintroduction of clozapine alone. This catatonia is reversible and it responds magnificently to the reintroduction of clozapine. And we conclude that patients and their caregivers need to be educated about the effects of abrupt cessation of clozapine administration. Copyright © 2016 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  5. A Level Set Discontinuous Galerkin Method for Free Surface Flows

    DEFF Research Database (Denmark)

    Grooss, Jesper; Hesthaven, Jan


    We present a discontinuous Galerkin method on a fully unstructured grid for the modeling of unsteady incompressible fluid flows with free surfaces. The surface is modeled by embedding and represented by a levelset. We discuss the discretization of the flow equations and the level set equation...... as well a various ways of advancing the equations in time using velocity projection techniques. The efficacy of the method for the representation of the levelset and its reinitialization is discussed and several numerical tests confirm the robustness and versatility of the proposed scheme....

  6. A discontinuous Galerkin method for Vlasov - like systems (United States)

    Gamba, I. M.; Cheng, Yingda; Morrison, P. J.


    The discontinuous Galerkin (DG) method developed by some of us for integrating the Vlasov-Poisson system is described and generalized. Higher order polynomials on basis elements are used and extensive error analyses, including recurrence properties, are discussed. The method is conservative and preserves positivity of the distribution function. Several linear and nonlinear examples are treated that elucidate the DG methods ability to resolve filamentation and obtain high resolution BGK states. PJM was upported by U.S. Dept. of Energy Contract # DE-FG05-80ET-53088.

  7. Cryogenic thermal storage system for discontinuous industrial vacuum processes (United States)

    Bruzzi, M.; Chesi, A.; Baldi, A.; Tarani, F.; Mori, R.; Scaringella, M.; Carnevale, E.


    Phase Change Materials are proposed for refrigerating systems in discontinuous industrial vacuum processes where temperatures as low as -140 ÷ -100°C are necessary within time-frames representing 10÷20% of total operating time. An application is proposed for cooling systems used in a Physical Vapour Deposition (PVD) apparatus. A prototype has been manufactured which couples a cryopump with a reservoir filled with MethylCycloPentane (MCP-C6H12) and a distribution line where nitrogen in the gaseous state is flowing. Preliminary tests show that temperatures of about -120°C are actually achieved within time windows compatible with PVD applications.

  8. The influence of Discontinuous Transmission on RXQUAL statistics in GSM

    DEFF Research Database (Denmark)

    Wigard, Jeroen; Nielsen, Thomas Toftegaard; Skjærris, Søren


    Discontinuous transmission (DTX) is a feature which has been reported to give about 2.5 dB gain in C/I performance. However in real life, network operators, who switch on DTX, often experience a loss in performance. They measure the performance by the RXQUAL distribution. RXQUAL is a quality...... inaccuracies, is studied in this paper. It is also explained why the quality in a network, where DTX is turned on, seems to decrease. Real life measurements and simulation results are shown...

  9. [Selection of landscape metrics for urban forest based on simulated landscapes]. (United States)

    Liu, Chang-Fu; Li, Jing-Ze; Li, Xiao-Ma; He, Xing-Yuan; Chen, Wei


    Based on the existing urban forest landscape of Shenyang, four landscape pattern gradients were simulated, and one existing landscape pattern gradient in accordance with the trend of these gradients was selected. By analyzing the responses of 28 landscape metrics for landscape fragmentation and patch shape complexity to various landscape pattern gradients, preference landscape metrics were selected for describing the degree of the two landscape pattern characteristics. The results showed that patch density (PD) and mean patch area (AREA_MN) regularly responded to the change of landscape fragmentation. The increase of landscape fragmentation resulted in an increase of PD value while a decrease of AREA_MN value. Patch shape complexity of area weighted mean perimeter area ratio (PARA_AM) coincided with the gradients of landscape pattern. PARA AM value increased with increasing patch shape complexity, which precisely characterized the degree of patch shape complexity.

  10. Biography of an Industrial Landscape

    DEFF Research Database (Denmark)

    Riesto, Svava

    Biography of an Industrial Landscape tells the story of one of the most significant urban redevelopment projects in northern Europe at the turn of the century. Examining the reinvention of the Carlsberg brewery site in Copenhagen as a city district, Svava Riesto unpacks the deeper assumptions about...... value that lie behind contemporary design, spatial planning and heritage praxis. In particular, Riesto examines ways of valuing a vital yet seldom explicitly discussed feature of industrial landscapes: open space. Carlsberg’s industrial open spaces were largely disregarded during the redevelopment...... to landscape research, the Carlsberg site’s open spaces are presented anew as an interplay of materials, practices and the imagination – shaped and reshaped by water, yeast, industrial working routines and conflicting ideas about the urban future....

  11. Changing wind-power landscapes

    DEFF Research Database (Denmark)

    Möller, Bernd


    of determining the likely visual-impact on landscapes and population, taking into account that there is no clear threshold for perceived adverse visual-impact. A geographical information system (GIS) has been used to build a regional landscape model for Northern Jutland County, which is used to assess visibility...... more stringent. One of the factors inhibiting development seems to be uncertainty in planning about the future impact on landscapes. Visual impact has rarely been an issue so far, but ever-increasing turbine size and less local involvement may change this. This paper presents a deterministic approach...... of turbines in the period of 1990 to 2010, based on historical and planning data. Multiple viewsheds are calculated for various thresholds of visual impact and overlaid with population and land-use data. The results show that a decrease in the number of turbines by about 40% and an increase in installed...

  12. International Documents on Landscape Restoration

    Directory of Open Access Journals (Sweden)

    Olga Pouperová


    Full Text Available In the theory and practice of cultural monuments protection, including garden art monuments and landscape protection, it has been often referred to international conventions and other international documents relating to this protection. Necessary condition for these documents to be adequately used in the practice is the precise understanding of their legal nature and a question arising therefrom, if and to what extent and to whom are those documents binding.The aim of this paper is to provide an analysis of the international documents relating to the landscape restoration. Following the analysis, the authors explore the scope and way of transposition of these documents and obligation arising therefrom into the Czech legal order. In the general part the authors analyse knowledge of the current jurisprudence on treaties and other international documents. They focus on the issue of the legal force of such documents, both on the international and national level. In the following part the authors deal with international documents on landscape restoration, explain legal nature of those documents and explicate whether the documents are formally legally binding or whether they may have other practical effects. The legally binding international treaties on the landscape protection include in particular the Convention on the Protection of the World Cultural and Natural Heritage (Paris, 1972 and the European Landscape Convention (Florence, 2000. As regard legally non-binding acts of international non-governmental organizations, the paper discusses the charters of the International Council on Monuments and Sites (ICOMOS, the Venice Charter of 1964 and the Florence Charter of 1981. Mentioned is also the Athens Charter (1933, respectively the New Athens Charter of 1998 dealing with the landscape in terms of the principles of urban planning.

  13. Predictability of evolutionary trajectories in fitness landscapes.

    Directory of Open Access Journals (Sweden)

    Alexander E Lobkovsky


    Full Text Available Experimental studies on enzyme evolution show that only a small fraction of all possible mutation trajectories are accessible to evolution. However, these experiments deal with individual enzymes and explore a tiny part of the fitness landscape. We report an exhaustive analysis of fitness landscapes constructed with an off-lattice model of protein folding where fitness is equated with robustness to misfolding. This model mimics the essential features of the interactions between amino acids, is consistent with the key paradigms of protein folding and reproduces the universal distribution of evolutionary rates among orthologous proteins. We introduce mean path divergence as a quantitative measure of the degree to which the starting and ending points determine the path of evolution in fitness landscapes. Global measures of landscape roughness are good predictors of path divergence in all studied landscapes: the mean path divergence is greater in smooth landscapes than in rough ones. The model-derived and experimental landscapes are significantly smoother than random landscapes and resemble additive landscapes perturbed with moderate amounts of noise; thus, these landscapes are substantially robust to mutation. The model landscapes show a deficit of suboptimal peaks even compared with noisy additive landscapes with similar overall roughness. We suggest that smoothness and the substantial deficit of peaks in the fitness landscapes of protein evolution are fundamental consequences of the physics of protein folding.

  14. Predictability of evolutionary trajectories in fitness landscapes. (United States)

    Lobkovsky, Alexander E; Wolf, Yuri I; Koonin, Eugene V


    Experimental studies on enzyme evolution show that only a small fraction of all possible mutation trajectories are accessible to evolution. However, these experiments deal with individual enzymes and explore a tiny part of the fitness landscape. We report an exhaustive analysis of fitness landscapes constructed with an off-lattice model of protein folding where fitness is equated with robustness to misfolding. This model mimics the essential features of the interactions between amino acids, is consistent with the key paradigms of protein folding and reproduces the universal distribution of evolutionary rates among orthologous proteins. We introduce mean path divergence as a quantitative measure of the degree to which the starting and ending points determine the path of evolution in fitness landscapes. Global measures of landscape roughness are good predictors of path divergence in all studied landscapes: the mean path divergence is greater in smooth landscapes than in rough ones. The model-derived and experimental landscapes are significantly smoother than random landscapes and resemble additive landscapes perturbed with moderate amounts of noise; thus, these landscapes are substantially robust to mutation. The model landscapes show a deficit of suboptimal peaks even compared with noisy additive landscapes with similar overall roughness. We suggest that smoothness and the substantial deficit of peaks in the fitness landscapes of protein evolution are fundamental consequences of the physics of protein folding.

  15. Energy Landscape of Social Balance (United States)

    Marvel, Seth A.; Strogatz, Steven H.; Kleinberg, Jon M.


    We model a close-knit community of friends and enemies as a fully connected network with positive and negative signs on its edges. Theories from social psychology suggest that certain sign patterns are more stable than others. This notion of social “balance” allows us to define an energy landscape for such networks. Its structure is complex: numerical experiments reveal a landscape dimpled with local minima of widely varying energy levels. We derive rigorous bounds on the energies of these local minima and prove that they have a modular structure that can be used to classify them.

  16. Rapa Nui Landscapes of Construction

    Directory of Open Access Journals (Sweden)

    Sue Hamilton


    Full Text Available Rapa Nui (Easter Island is the most remote inhabited spot in the world. It is famous for its gigantic stone statues, which have been the focus of much archaeological study. The new Rapa Nui Landscapes of Construction Project, described in this article, adopts a more holistic approach, aiming to place the statues and associated monumental structures in the context of the wider landscape of settlement and cultivation. It also concentrates on the processes of construction as much as the final products, with an emphasis on quarries and other places of construction, approached through multiple methods of field exploration.

  17. Landscape: between Loss and History


    Besse, Jean-Marc


    The discovery of landscape, according to Georg Simmel, was above all the experience of a twofold separation: separation of subject and world, on the one hand, and separation of landscape and nature, on the other. Double separation or double extraction, typically modern, which reflects a movement towards the individualization of forms of interior and exterior life. It is in the withdrawal of the human being from his/her worldly involvements, and in his/her capacity to regard the world, so to s...

  18. Landscape genetics: combining landscape ecology and population genetics (United States)

    Stephanie Manel; Michael K. Schwartz; Gordon Luikart; Pierre Taberlet


    Understanding the processes and patterns of gene flow and local adaptation requires a detailed knowledge of how landscape characteristics structure populations. This understanding is crucial, not only for improving ecological knowledge, but also for managing properly the genetic diversity of threatened and endangered populations. For nearly 80 years, population...

  19. Landscape practise and key concepts for landscape sustainability

    DEFF Research Database (Denmark)

    Brandt, Jesper; Christensen, Andreas Aagaard; Svenningsen, Stig Roar


    time, the practice behind such conceptual frameworks has survived in many land use systems, being a fundamental source of inspiration for the modern challenge of landscape sustainability. Here, the concept and practice of carrying capacity is used as an example. We provide a modern interpretation...

  20. New Landscapes in the City, or Learning from Landscape

    Directory of Open Access Journals (Sweden)

    Barbara Engel


    Full Text Available The article considers new forms of relationship between city and landscape. It also reveals one of the major challenges for planning and urban governance: to use the creative potential which is formed in different pioneering or temporary uses and activities of people for sustainable development of the urban environment.

  1. Tubes of discontinuous solutions of dynamical systems and their stability (United States)

    Sesekin, A. N.; Zhelonkina, N. I.


    The article is devoted to investigation of nonlinear dynamical systems which applies the generalized effect. The generalized effect (or impulses) is the result of the presence on the right part of the system a generalized derivative of the function of bounded variation. Such system contains incorrect operation of multiplication of discontinuous function on the generalized function from the point of view of the theory of distributions. This incorrectness is overcome by the approximation of the generalized functions in the right part of system by the sequence of smooth approximations of the generalized influences by analogy with sequential approach of the theory of the generalized functions. This sequence generates a sequence of smooth solutions. Then limit of a sequence of smooth solutions is considered. If such limit exists it is offered to be used as a solution. The solution is understood as partial pointwise limit of such sequence if a sequence of smooth solutions does not converge. Such partial limits constitute a tube of solutions. The sufficient conditions are received for stability of tubes of discontinuous solutions.

  2. Discontinuity of Breastfeeding Care: "There's No Captain of the Ship". (United States)

    Garner, Christine D; Ratcliff, Stephannie L; Thornburg, Loralei L; Wethington, Elaine; Howard, Cynthia R; Rasmussen, Kathleen M


    Breastfeeding rates in the United States are suboptimal. Health professionals (HPs) have a unique opportunity to support breastfeeding because of the frequency and timing of their visits with mothers and infants as well as their call by professional organizations to do so. The objective of this study was to understand HPs' perceived roles and experiences with providing breastfeeding-related care. In-depth qualitative interviews were conducted with 34 HPs (obstetricians, midwives, pediatricians, nurses, and lactation consultants) who care for pregnant or lactating women. Interviews were audio-recorded, transcribed, and verified for accuracy; content analysis was used to identify themes using a grounded theory approach. The overarching theme was discontinuity in breastfeeding care across the continuum. Most HPs relied on other HPs to provide breastfeeding care, which resulted from and contributed to problematic gaps in care that were reported. A minority of HPs attempted to bridge gaps in breastfeeding care or improve continuity. Contributing to the discontinuity were a lack of time, lack of skills, inconsistent messages, and low communication across stages of care. HPs were unsure whether their help was effective and whether required follow-up was completed. Despite HPs' recognition of breastfeeding as the best choice for infant feeding, breastfeeding care may be disjointed and a barrier to achieving breastfeeding recommendations. These problems should be investigated and systemically addressed in future research so that maternal-infant dyad breastfeeding care can be improved.

  3. A coupled electro-thermal Discontinuous Galerkin method (United States)

    Homsi, L.; Geuzaine, C.; Noels, L.


    This paper presents a Discontinuous Galerkin scheme in order to solve the nonlinear elliptic partial differential equations of coupled electro-thermal problems. In this paper we discuss the fundamental equations for the transport of electricity and heat, in terms of macroscopic variables such as temperature and electric potential. A fully coupled nonlinear weak formulation for electro-thermal problems is developed based on continuum mechanics equations expressed in terms of energetically conjugated pair of fluxes and fields gradients. The weak form can thus be formulated as a Discontinuous Galerkin method. The existence and uniqueness of the weak form solution are proved. The numerical properties of the nonlinear elliptic problems i.e., consistency and stability, are demonstrated under specific conditions, i.e. use of high enough stabilization parameter and at least quadratic polynomial approximations. Moreover the prior error estimates in the H1-norm and in the L2-norm are shown to be optimal in the mesh size with the polynomial approximation degree.

  4. Discontinuation of mechanical ventilation in patients with amyotrophic lateral sclerosis. (United States)

    Borasio, G D; Voltz, R


    Mechanical ventilation, both invasive and non-invasive, may be an effective means of improving the quality of life and prolonging the survival of patients suffering from amyotrophic lateral sclerosis (ALS). However, the attitude towards this palliative measure varies greatly between different centres and countries. One of the arguments cited against this procedure is the fear that a patient might request the physician to discontinue life support. We believe that the question of withdrawal of mechanical ventilation can only be meaningfully addressed in the general context of palliative care. Here, we review possible modes of action in response to a patient's request for life support withdrawal and their medical, legal and ethical implications. We propose that the following goals should be pursued: (1) prevention of unwanted ventilation by early, open discussion with patient and relatives, (2) delivery of optimal palliative care by the caring team, (3) recognition of the patient's right to withdraw his/her consent to an invasive medical procedure. If these goals have been met, it may be medically, legally and ethically justified for the physician to take all necessary steps to ensure a peaceful death after discontinuation of life support.

  5. Bifurcation in autonomous and nonautonomous differential equations with discontinuities

    CERN Document Server

    Akhmet, Marat


    This book is devoted to bifurcation theory for autonomous and nonautonomous differential equations with discontinuities of different types. That is, those with jumps present either in the right-hand-side or in trajectories or in the arguments of solutions of equations. The results obtained in this book can be applied to various fields such as neural networks, brain dynamics, mechanical systems, weather phenomena, population dynamics, etc. Without any doubt, bifurcation theory should be further developed to different types of differential equations. In this sense, the present book will be a leading one in this field. The reader will benefit from the recent results of the theory and will learn in the very concrete way how to apply this theory to differential equations with various types of discontinuity. Moreover, the reader will learn new ways to analyze nonautonomous bifurcation scenarios in these equations. The book will be of a big interest both for beginners and experts in the field. For the former group o...

  6. Facilitated synchronization of complex networks through a discontinuous coupling strategy (United States)

    Chen, L.; Qiu, C.; Huang, H. B.; Qi, G. X.; Wang, H. J.


    Synchronization stability in complex networks is a topic of theoretical interest and practical importance. Increasing effort has been devoted to the enhancement of synchronizability of networks, or more specifically, the design of synchronizable networks. However, most previous attempts turn the coupling weight/gradient or change the topological interactions, which sometimes is not manageable. In this paper, by adopting a simple kind of discontinuous coupling strategy: the uniform on-off coupling scheme, with on-off period being comparable to the timescale of node dynamics, the problem is solved within the framework of the master stability function. The results show that, this strategy can greatly increase the stable region of synchronization, which means the size of synchronizable networks can be much larger than the traditional case, without any changes of their connections. Furthermore, the synchronization speed can be accelerated considerably, which is even higher than the previous optimal case. The mechanism of the facilitation is revealed and shows that the continuous coupling in fact is one of the worst choices for synchronization in the view of discontinuous coupling strategy. The coupling cost required for synchronization is also examined, which is approximately the same as the continuous coupling.

  7. Martian Landscapes in Motion (United States)

    Mattson, Sarah; McEwen, Alfred; Kirk, Randolph; Howington-Kraus, Elpitha; Chojnacki, Matthew; Runyon, Kirby; Cremonese, Gabriele; Re, Cristina


    RISE orthorectified image sequences makes it possible to conduct accurate change detection studies of active processes on Mars. Some examples of studies of active landscapes on Mars using HiRISE DTMs and orthoimage sequences include: dune and ripple motion (Bridges et al., 2012, Nature), recurring slope lineae (RSL) (McEwen et al., 2011, Science; McEwen et al., 2013, Nature Geoscience), gully activity (Dundas et al., 2012, Icarus), and polar processes (Hansen et al., 2011, Science; Portyankina et al. 2013, Icarus,). These studies encompass images from multiple Mars years and seasons. Sequences of orthoimages make it possible to generate animated gifs or movies to visualize temporal changes ( They can also be brought into geospatial software to quantitatively map and record changes. The ability to monitor the surface of Mars at high spatial resolution with frequent repeat images has opened up our insight into seasonal and interannual changes, further increasing our understanding of Mars as an active planet.

  8. Land classification based on hydrological landscape units

    NARCIS (Netherlands)

    Gharari, S.; Fenicia, F.; Hrachowitz, M.; Savenije, H.H.G.


    This paper presents a new type of hydrological landscape classification based on dominant runoff mechanisms. Three landscape classes are distinguished: wetland, hillslope and plateau, corresponding to three dominant hydrological regimes: saturation excess overland flow, storage excess sub-surface

  9. Clarifying integrative research concepts in landscape ecology

    NARCIS (Netherlands)

    Tress, G.; Tress, B.; Fry, G.


    Integrative research approaches are intensely discussed in landscape ecology, in academia and in research policy. However, confusion over the terminology hampers communication. Many current landscape ecological research projects have difficulties to agree on a common understanding of the core

  10. Landscaping of highway medians at intersections : summary. (United States)


    The most obvious benefit of landscaped medians is highway beautification, but they have also been found to enhance safety. Landscaping helps define turn lanes and crosswalks, adding to roadway safety. : Placement and specifications of highway landsca...

  11. Benefits and Risks Associated with Landscapes (United States)

    To fully reap the benefits that lawns and landscapes can provide our urban and suburban communities, these green spaces must be well-maintained. The landscaping initiative helps manage the benefits and risks associated with lawn care.

  12. Sustainable multifunctional landscapes: a review to implementation

    CSIR Research Space (South Africa)

    O'Farrell, PJ


    Full Text Available Historic land use practices have dramatically altered landscapes across all scales, homogenising them and restricting opportunities for humans and wildlife. The need for multifunctional landscapes which simultaneously provide food security...

  13. Bipolarity and Ambivalence in Landscape Architecture


    Koh, J.


    Our discipline of landscape architecture contains bipolarity, not only in terms of landscape and architecture but also because the idea of landscape is both aesthetic and scientific. Furthermore, within landscape architecture there is a gap between design (as implied by architecture) and planning (implying land-use plan and policy orientation) on one hand, and a similar gap between design (associated with artistic activity, concerned with aesthetics as well as science) and research (considere...


    Directory of Open Access Journals (Sweden)

    Stanisław Jacek Bacior


    Full Text Available Landscape evaluation process requires access to particular information resources making it possible to regionalize (divide into zones the area under investigation. Thus, the starting point is landscape assessment and evaluation followed by regionalization. As a result of this step, we determine certain areas that are homogenous with regards to their landscape assets Keywords: assessing landscape, structure of rural areas, spatial planning of rural areas.

  15. Evidence and opportunities for integrating landscape ecology into natural resource planning across multiple-use landscapes (United States)

    Trammel, E. Jamie; Carter, Sarah; Haby, Travis S.; Taylor, Jason J.


    Enhancing natural resource management has been a focus of landscape ecology since its inception, but numerous authors argue that landscape ecology has not yet been effective in achieving the underlying goal of planning and designing sustainable landscapes. We developed nine questions reflecting the application of fundamental research topics in landscape ecology to the landscape planning process and reviewed two recent landscape-scale plans in western North America for evidence of these concepts in plan decisions. Both plans considered multiple resources, uses, and values, including energy development, recreation, conservation, and protection of cultural and historic resources. We found that land use change and multiscale perspectives of resource uses and values were very often apparent in planning decisions. Pattern-process relationships, connectivity and fragmentation, ecosystem services, landscape history, and climate change were reflected less frequently. Landscape sustainability was considered only once in the 295 decisions reviewed, and outputs of landscape models were not referenced. We suggest six actionable opportunities for further integrating landscape ecology concepts into landscape planning efforts: 1) use landscape sustainability as an overarching goal, 2) adopt a broad ecosystem services framework, 3) explore the role of landscape history more comprehensively, 4) regularly consider and accommodate potential effects of climate change, 5) use landscape models to support plan decisions, and 6) promote a greater presence of landscape ecologists within agencies that manage large land bases and encourage active involvement in agency planning efforts. Together these actions may improve the defensibility, durability, and sustainability of landscape plan decisions.

  16. Landscape Builder: software for the creation of initial landscapes for LANDIS from FIA data (United States)

    William. Dijak


    I developed Landscape Builder to create spatially explicit landscapes as starting conditions for LANDIS Pro 7.0 and LANDIS II landscape forest simulation models from classified satellite imagery and Forest Inventory and Analysis (FIA) data collected over multiple years. LANDIS Pro and LANDIS II models project future landscapes by simulating tree growth, tree species...

  17. Interacting effects of landscape context and habitat quality on flower visiting insects in agricultural landscapes

    NARCIS (Netherlands)

    Kleijn, D.; Langevelde, van F.


    Landscape context and habitat quality may have pronounced effects on the diversity of flower visiting insects. We investigated whether the effects of landscape context and habitat quality on flower visiting insects interact in agricultural landscapes in the Netherlands. Landscape context was

  18. Experimental evidence of landscape reorganization under changing external forcing: implications to climate-driven knickpoints (United States)

    Singh, Arvind; Tejedor, Alejandro; Grimaud, Jean-Louis; Foufoula-Georgiou, Efi


    Understanding and quantifying geomorphic and topologic re-organization of landscape in response to changing climatic or tectonic forcing is of scientific and practical interest. Although several studies have addressed the large-scale response (e.g., change in mean relief), studies on the smaller-scale drainage pattern re-organization and quantification of landscape vulnerability to the timing, magnitude, and frequency of changing forcing are lacking. To that goal, a series of controlled laboratory experiments were conducted to study the effect of changing precipitation patterns on landscape evolution at the short and long-time scales. High resolution digital elevation (DEM) both in space and time were measured for a range of rainfall patterns and uplift rates. Results from our study show a distinct signature of the precipitation increase on the probabilistic and geometrical structure of landscape features, evident in widening and deepening of channels and valleys, change in drainage patterns within sub-basins and change in the space-time structure of erosional and depositional events. A spatially explicit analysis of the locus of these erosional and depositional events show an acceleration of erosion in the hillslopes when the rainfall intensity is increased, while the incision in fluvial channels is slowed down exhibiting a sediment-flux dependent behavior. Finally, we document the changes in the longitudinal river profiles with increasing precipitation intensity, revealing the formation of knickpoints at certain confluences where large discontinuities in the ratio Qs/Qw are observed.

  19. Axion landscape and natural inflation

    Energy Technology Data Exchange (ETDEWEB)

    Higaki, Tetsutaro, E-mail: [Theory Center, KEK, 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Takahashi, Fuminobu, E-mail: [Department of Physics, Tohoku University, Sendai 980-8578 (Japan); Kavli Institute for the Physics and Mathematics of the Universe (WPI), Todai Institutes for Advanced Study, University of Tokyo, Kashiwa 277-8583 (Japan)


    Multiple axions form a landscape in the presence of various shift symmetry breaking terms. Eternal inflation populates the axion landscape, continuously creating new universes by bubble nucleation. Slow-roll inflation takes place after the tunneling event, if a very flat direction with a super-Planckian decay constant arises due to the alignment mechanism. We study the vacuum structure as well as possible inflationary dynamics in the axion landscape scenario, and find that the inflaton dynamics is given by either natural or multi-natural inflation. In the limit of large decay constant, it is approximated by the quadratic chaotic inflation, which however is disfavored if there is a pressure toward shorter duration of inflation. Therefore, if the spectral index and the tensor-to-scalar ratio turn out to be different from the quadratic chaotic inflation, there might be observable traces of the bubble nucleation. Also, the existence of small modulations to the inflaton potential is a common feature in the axion landscape, which generates a sizable and almost constant running of the scalar spectral index over CMB scales. Non-Gaussianity of equilateral type can also be generated if some of the axions are coupled to massless gauge fields.

  20. Surface fluxes in heterogeneous landscape

    Energy Technology Data Exchange (ETDEWEB)

    Bay Hasager, C.


    The surface fluxes in homogeneous landscapes are calculated by similarity scaling principles. The methodology is well establish. In heterogeneous landscapes with spatial changes in the micro scale range, i e from 100 m to 10 km, advective effects are significant. The present work focus on these effects in an agricultural countryside typical for the midlatitudes. Meteorological and satellite data from a highly heterogeneous landscape in the Rhine Valley, Germany was collected in the large-scale field experiment TRACT (Transport of pollutants over complex terrain) in 1992. Classified satellite images, Landsat TM and ERS SAR, are used as basis for roughness maps. The roughnesses were measured at meteorological masts in the various cover classes and assigned pixel by pixel to the images. The roughness maps are aggregated, i e spatially averaged, into so-called effective roughness lengths. This calculation is performed by a micro scale aggregation model. The model solves the linearized atmospheric flow equations by a numerical (Fast Fourier Transform) method. This model also calculate maps of friction velocity and momentum flux pixel wise in heterogeneous landscapes. It is indicated how the aggregation methodology can be used to calculate the heat fluxes based on the relevant satellite data i e temperature and soil moisture information. (au) 10 tabs., 49 ills., 223 refs.

  1. Ecological networks in urban landscapes

    NARCIS (Netherlands)

    Cook, E.A.


    This research focuses on the topic of ecological networks in urban landscapes. Analysis and planning of ecological networks is a relatively new phenomenon and is a response to fragmentation and deterioration of quality of natural systems. In agricultural areas and with existing nature




  3. Renewable energy from urban landscapes (United States)

    Utilizing biomass from urban landscapes could significantly contribute to the nation’s renewable energy needs. In 2007, an experiment was begun to evaluate the biomass potential from a bermudagrass, Cynodon dactylon var. dactylon (L.) Pers., lawn in Woodward, OK and to estimate the potential biomas...

  4. Fisher population and landscape genetics (United States)

    Michael Schwartz; Joel Saunder; Kristine L. Pilgrim; Ray Vinkey; Michael K. Lucid; Sean Parks; Nathan Albrecht


    This talk provides a population and landscape genetic overview of fishers in Idaho and Montana. We start by discussing some of our initial findings using mitochondrial DNA (Vinkey et al. 2006, Schwartz 2007, Knaus et al. 2011). On balance these results demonstrate the uniqueness of a native haplotype that persisted in the Bitterroot-Selway Ecosystem. They also show the...

  5. A heuristic for landscape management (United States)

    Martín Alfonso B. Mendoza; Jesús S. Zepeta; Juan José A. Fajardo


    The development of landscape ecology has stressed out the importance of spatial and sequential relationships as explanations to forest stand dynamics, and for other natural ambiences. This presentation offers a specific design that introduces spatial considerations into forest planning with the idea of regulating fragmentation and connectivity in commercial forest...

  6. Landscape design methods in architecture

    NARCIS (Netherlands)

    Jauslin, D.T.


    Landscape has been used as a metaphor or conceptual reference for an increasing amount of excellent architectural projects in the last two decades. The phenomenon seems to be a substantial innovation of architecture with an interesting potential for artistic, social and ecological gains. To be able

  7. Water-wise Landscaping: Practical Turfgrass Areas


    Kopp, Kelly; Johnson, Paul


    Of the seven guiding principles of water-wise landscaping (a.k.a. Xeriscaping™), the most controversial involves the use of turfgrass in the landscape. At times it has seemed that water-wise landscaping might not allow for the use of turfgrasses at all.

  8. Introduction to Landscaping (Adult). Instructor Guide. (United States)

    Harris, Clark Richard; Feilner, Veronica, Ed.

    This module, intended for adult instruction, is an introduction to landscaping designed to help students become familiar with landscaping terminology and concepts. The material is planned for six 2-hour classes. The first three lessons aid students in interpreting landscape plans and understanding some of the reasons for plant placement and…

  9. The Wadden area, a multiple landscape?

    NARCIS (Netherlands)

    Boomars, E.A.M.


    The concept ‘multiple landscapes’ implies that one particular landscape can entail different landscapes. Various social groups can ascribe different meanings to the same physical landscape. In this paper the Dutch Wadden area (Lancewad project) is analysed and described as a case of a multiple

  10. Ecosystem services in changing landscapes: An introduction (United States)

    Louis Iverson; Cristian Echeverria; Laura Nahuelhual; Sandra. Luque


    The concept of ecosystem services from landscapes is rapidly gaining momentum as a language to communicate values and benefits to scientists and lay alike. Landscape ecology has an enormous contribution to make to this field, and one could argue, uniquely so. Tools developed or adapted for landscape ecology are being increasingly used to assist with the quantification...

  11. Measuring Visible Space to Assess Landscape Openness

    NARCIS (Netherlands)

    Weitkamp, Gerd; Bregt, Arnold; Van Lammeren, Ron


    This paper presents and discusses a procedure for measuring landscape openness, which is an important characteristic of the visual landscape. The procedure aims to ensure the quality of descriptions of landscape openness while being flexible enough to produce descriptions suitable for various

  12. Measuring visible space to assess landscape openness

    NARCIS (Netherlands)

    Weitkamp, S.G.; Bregt, A.K.; Lammeren, van R.J.A.


    This paper presents and discusses a procedure for measuring landscape openness, which is an important characteristic of the visual landscape. The procedure aims to ensure the quality of descriptions of landscape openness while being flexible enough to produce descriptions suitable for various

  13. Sustaining ecosystem services in cultural landscapes

    Directory of Open Access Journals (Sweden)

    Tobias Plieninger


    Full Text Available Classical conservation approaches focus on the man-made degradation of ecosystems and tend to neglect the social-ecological values that human land uses have imprinted on many environments. Throughout the world, ingenious land-use practices have generated unique cultural landscapes, but these are under pressure from agricultural intensification, land abandonment, and urbanization. In recent years, the cultural landscapes concept has been broadly adopted in science, policy, and management. The interest in both outstanding and vernacular landscapes finds expression in the UNESCO World Heritage Convention, the European Landscape Convention, and the IUCN Protected Landscape Approach. These policies promote the protection, management, planning, and governance of cultural landscapes. The ecosystem services approach is a powerful framework to guide such efforts, but has rarely been applied in landscape research and management. With this paper, we introduce a special feature that aims to enhance the theoretical, empirical and practical knowledge of how to safeguard the resilience of ecosystem services in cultural landscapes. It concludes (1 that the usefulness of the ecosystem services approach to the analysis and management of cultural landscapes should be reviewed more critically; (2 that conventional ecosystem services assessment needs to be complemented by socio-cultural valuation; (3 that cultural landscapes are inherently changing, so that a dynamic view on ecosystem services and a focus on drivers of landscape change are needed; and (4 that managing landscapes for ecosystem services provision may benefit from a social-ecological resilience perspective.

  14. Designing landscapes for northern Nevada's arid climate (United States)

    Heidi Kratsch; JoAnne Skelly


    Landscape design is both art and organization. Anyone can plant trees or shrubs in a row, but that isn't a designed landscape. Landscape design is placing plants and structures in ways that organize and enrich an outdoor space to have agreeable and useful relationships with the natural environment. A good design makes the best use of the space available and the...

  15. Contribution of strong discontinuities to the power spectrum of the solar wind. (United States)

    Borovsky, Joseph E


    Eight and a half years of magnetic field measurements (2(22) samples) from the ACE spacecraft in the solar wind at 1 A.U. are analyzed. Strong (large-rotation-angle) discontinuities in the solar wind are collected and measured. An artificial time series is created that preserves the timing and amplitudes of the discontinuities. The power spectral density of the discontinuity series is calculated and compared with the power spectral density of the solar-wind magnetic field. The strong discontinuities produce a power-law spectrum in the "inertial subrange" with a spectral index near the Kolmogorov -5/3 index. The discontinuity spectrum contains about half of the power of the full solar-wind magnetic field over this "inertial subrange." Warnings are issued about the significant contribution of discontinuities to the spectrum of the solar wind, complicating interpretation of spectral power and spectral indices.

  16. Characterization of a Coplanar Waveguide Open Stub-Based Discontinuity for MMICs and Filter Applications

    Directory of Open Access Journals (Sweden)

    Rizwan Masood


    Full Text Available This paper presents the analysis and design of an open stub-based two-port discontinuity in a coplanar waveguide. The discontinuity has a good bandpass response and the required design characteristics were achieved by using the method of moments (MOM and the finite integration technique (FIT. The analysis is found to be computationally efficient which makes the discontinuity suitable for use in complex structure applications. The analysis of the discontinuity is also formulated using the quasi-static finite-difference technique. The proposed discontinuity structure finds applications in RFICs and MMICs. Finally, the application of the discontinuity is supported by the simulated design of a broadband bandpass filter on an MMIC with a relative bandwidth of 96%. The filter is found to have a miniature size and a fairly good stop band rejection.

  17. How can landscape management be enhanced by farming systems ? A landscape agronomy perspective


    Marraccini, Élisa; Lardon, Sylvie; Rapey, Hélène; DEBOLINI, Marta,; Thenail, Claudine; Benoit, Marc


    Agronomists are faced to the multiple stakeholders’ landscape design as a rising issue in the management of farming systems. Furthermore, the European Landscape Convention (ELC) has formally acknowledged the expectations of local stakeholders and decision-makers for a greater support to protect manage and plan the landscapes. A renewed perspective of agronomy on landscape research has recently tried to tackle this challenge. This perspective, called “landscape agronomy” (LA), strives to widen...



    Matisovs, Ivars


    The paper deals with urban landscape individualities in the cities and towns of Latgale region. Also show facilities and methods of integrated assessment of urban landscape quality. Article provides information about specifics of urban landscape and factors, that have influence on landscape quality. The paper presents the results of Daugavpils and Rēzekne urban landscape quality complex assessment, that have been realised in 2003- 2005. This results don’t establish significant disparities bet...

  19. Landscape and landscape ecology as factors in the process of integrated spatial management


    Brandt, Jesper


    During the last years, the landscape definition related to the European Landscape Convention has been more and more recognized among scientists and planners dealing with different aspects of landscapes. Sometimes the definition has been abbreviated to the sentence: ‘ an area, as perceived by people', see, e.g. (Olwig 2005), thus focusing on the mental construction of the landscape concept. Indeed, this perceptional aspect is also crucial to understand the ongoing mental battles on landscape i...

  20. National study of discontinuation of long-term opioid therapy among veterans. (United States)

    Vanderlip, Erik R; Sullivan, Mark D; Edlund, Mark J; Martin, Bradley C; Fortney, John; Austen, Mark; Williams, James S; Hudson, Teresa


    Veterans have high rates of chronic pain and long-term opioid therapy (LTOT). Understanding predictors of discontinuation from LTOT will clarify the risks for prolonged opioid use and dependence among this population. All veterans with at least 90 days of opioid use within a 180-day period were identified using national Veteran's Health Affairs (VHA) data between 2009 and 2011. Discontinuation was defined as 6 months with no opioid prescriptions. We used Cox proportional hazards analysis to determine clinical and demographic correlates for discontinuation. A total of 550,616 veterans met criteria for LTOT. The sample was primarily male (93%) and white (74%), with a mean age of 57.8 years. The median daily morphine equivalent dose was 26 mg, and 7% received high-dose (>100mg MED) therapy. At 1 year after initiation, 7.5% (n=41,197) of the LTOT sample had discontinued opioids. Among those who discontinued (20%, n=108,601), the median time to discontinuation was 317 days. Factors significantly associated with discontinuation included both younger and older age, lower average dosage, and having received less than 90 days of opioids in the previous year. Although tobacco use disorders decreased the likelihood of discontinuation, co-morbid mental illness and substance use disorders increased the likelihood of discontinuation. LTOT is common in the VHA system and is marked by extended duration of use at relatively low daily doses with few discontinuation events. Opioid discontinuation is more likely in veterans with mental health and substance use disorders. Further research is needed to delineate causes and consequences of opioid discontinuation. Published by Elsevier B.V.