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Sample records for subglottic polypoid mass

  1. POLYPOIDAL MASSES IN NOSE: A CLINICO - PATHOLOGICAL CORRELATION STUDY

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    Vijay Peruvaje

    2015-01-01

    Full Text Available INTRODUCTION : A polypoidal mass in the nasal cavity is a condition commonly encountered by the Otorhinolaryngologist. A diverse group of lesions may present themselves as polypoidal masses. A number of benign looking polyps often turn out to be malignant lesions or vice versa. OBJE CTIVES : This study is intended to clinically differentiate the various conditions presenting as nasal polypoidal lesions , to understand their exact nature by histopathological examination and thereby learn the relative incidence of individual conditions en countered. METHODOLOGY : D etailed history , clinical examination and histopathological examination of nasal polypoid masses were done in 73 patients. Incidence , clinical features and histopathological correlation of all the polypoidal masses were ascertained. RESULTS : O f the 73 cases , 53 (72.6% cases were non - neoplastic and 20 (27.4% were neoplastic lesions. The non - neoplastic lesions included nasal polyps , rhinosporidiosis , pyogenic granuloma and mucocoele. Benign neoplasms included inverted papilloma , haemangioma , angiofibroma , neurilemmoma and pleomorphic adenoma. Malignant neoplasms included squamous cell carcinoma , adenoid cystic carcinoma and olfactory neuroblastoma. CONCLUSION : P olypoidal masses in the nose may range from non - n eoplastic lesions to benign and malignant neoplasms with various histopathologic findings. It is impossible to distinguish between such lesions clinically. Hence , it is essential that all polypoidal masses removed should be evaluated histopathologically , t o make a correct diagnosis.

  2. Subglottic cysts and asymmetrical subglottic narrowing on neck radiograph

    International Nuclear Information System (INIS)

    Holinger, L.D.; Torium, D.M.; Anandappa, E.C.

    1988-01-01

    The congenital subglottic hemangioma typically appears as an asymmetric subglottic narrowing or mass on frontal neck radiograph. Therefore, soft tissue neck radiography has been advocated as a definitive non-operative approach for diagnosing these lesions. However, we have noted similar asymmetric subglottic narrowing in patients with acquired subglottic cysts. These retention cysts occur following long-term intubation in the neonate. The mechanism probably involves subglottic fibrosis which obstructs glands with subsequent cyst formation. Acquired subglottic cysts typically appear as an asymmetric narrowing on frontal or lateral soft tissue neck radiographs. These lesions may produce airway compromise but are effectively treated by forceps or laser removal. Acquired subglottic cysts must be included in the differential diagnosis of asymmetric subglottic narrowing. The definitive diagnosis is made by direct laryngoscopy, not soft tissue neck radiograph. (orig.)

  3. Extramedullary Plasmacytoma of the Larynx: A Case Report of Subglottic Localization

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    Jaqueline Ramírez-Anguiano

    2012-01-01

    Full Text Available Extramedullary plasmacytoma (EMP is a rare neoplasm of plasma cells, described in soft tissue outside the bone marrow. EMP of the larynx represents 0.04 to 0.45% of malignant tumors of the larynx. A male of 57 years old presented with hoarseness, dyspnea, and biphasic stridor of 2 months. The indirect laryngoscopy (IL revealed severe edema of the posterior commissure and a polypoid mass in the right posterior lateral subglottic wall. A biopsy of the subglottic mass was performed by a direct laryngoscopy (DL. The histopathologic diagnosis was EMP CD138+, therefore radiotherapy was given at 54 Gy in 30 sessions. The patient had an adequate postoperative clinical course and a new biopsy was performed having tumor-free margins. All laryngeal lesions should be biopsied prior to treatment to determine an accurate diagnosis to guide a proper management of the condition. Radiation therapy to the EMP is considered the treatment of choice, having local control rates of 80% to 100%. The subglottis is the least accessible area of view and the least frequent location of a laryngeal mass, nevertheless the otolaryngologist should always do a complete and systematic exam of the larynx when a tumor is suspected, to detect diagnoses such as a subglottic plasmacytoma.

  4. POLYPOID CYSTITIS: A FINDING AND DIFFERENTIAL DIAGNOSIS

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    D. Yu. Pushkar

    2011-01-01

    Full Text Available Background. Polypoid cystitis may simulate urothelial neoplasias cystoscopically and histologically. The frequency of polypoid cystitis is 0.38%; that among patients undergoing bladder catheterization is 6 %.Subjects and methods. The authors estimated the frequency of polypoid cystitis among chronic cystitis patients admitted to City Clinical Hospital Fifty, a base of the Clinic of Urology, Moscow State University of Medicine and Dentistry, in the period from February 2008 to February 2010. Out of 819 patients followed up, 3 who had diagnosed as having polypoid cystitis complained of pollakiuria, imperative micturate urges, and macrohematuria. They underwent ultrasonography, computed tomography, and cystoscopy; bladder masses measured 1.0, 7.0, and 11.5 cm, respectively; extensive growth was verified in 2 cases. Endoscopic studies identified procumbent rough-villous masses without well-defined outlines with the signs of bullous edema, decay, hemorrhages, and urinary salt encrustations. By taking into account the clinical picture and laboratory and instrumental findings, the authors suspected stage T3bNхMх bladder tumor in 2 patients and T1NхMх stage in 1. According to the European Association of Urology guidelines for management of bladder cancer, the patients underwent transurethral bladder resection. The patients were diagnosed as having polypoid cystitis on the basis of postmortem evidence.Results. In this study the frequency of polypoid cystitis was 37 %. Polypoid cystitis, a benign mass without a risk for malignancy, had signs of invasive transitional cell carcinoma.Conclusion. Such cases that rarely occur in practice are of clinical value and interest to urologists, pathologists, and oncologists.

  5. Ultrasonographic findings of uterine polypoid adenomyomas

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    Lee, Eun Ju [Ajou University School of Medicine, Suwon (Korea, Republic of)

    2002-12-15

    To characterize the ultrasonographic findings of polypoid adenomyoma of the uterus. Ultrasonographic findings of twenty seven patients with histologically confirmed polypoid adenomyoma were retrospectively reviewed. Ultrasonography (US) was performed in all patients while sonohysterography (SH) in fifteen patients and color Doppler sonography (CDS) in thirteen patients were additionally performed. Location, size, growth pattern, surface, margin from the endometrim and underlying myometrium, echogenecity and echotexture, presence and patterns of cystic areas, hemorrhage, and posterior shadowing of the endometrial or submucosal mass on US and SH were evaluated. The presence of blood flow and resistive index (RI) on CDS were also evaluated. On US and SH, the tumor location was the corpus in sixteen cases, fundus in eight, and isthmus in three cases, and the tumor size ranged from 0.5 to 6 cm (mean 3.5 cm). The tumors were polypoid in eighteen cases, sessile in four cases, and pedunculated in five cases, and three of them protruded into endocervical canal while two cases prolapsed through externals os. The surface was smooth in twenty six cases, lobulated in four and irregular in one. Nineteen cases had ill defined margin while eight cases, a well circumscribed margin. The mass was inhomogeneously isoechoic in twelve cases, homogeneously isoechoic in seven cases, homogeneously and inhomogeneously hyperechoic in four cases each, respectively. Cystic areas were seen in twenty cases, and there were three patterns of cystic areas: all solid mass (pattern 1, n=7), solid mass with cystic areas (pattern 2, n=18) and predominantly cystic mass (pattern 3, n=2). Eight cases had hemorrhage and seven had posterior shadowing. CDS showed a blood flow with range of RI from 0.19 to 0.74 (mean 0.47). Other findings included adenomyosis in sixteen cases, leiomyoma in three, and endometrial thickening and mass in one each, respectively. Polypoid adenomyoma can be characterized as a

  6. Giant polypoid gastric heterotopia of jejunum

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    Suresh Ramchandra Shenovi Mandrekar

    2016-01-01

    Full Text Available Heterotopic gastric tissue has been described in various parts of the gastrointestinal tract as an incidental finding. However, its presentation as a mass in the jejunum with obstructive manifestations is a rare event. We report here a rare case of giant polypoid gastric heterotopia in the jejunum that presented with intestinal obstruction in a 22-year-old female, along with a brief review of the literature.

  7. Polypoid cystitis mimicking bladder tumor: a case report

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    Choi, Pil Yeob; Kwon, Oh Jun; Kim, Jong Kuk

    2002-01-01

    Polypoid cystitis without a history of catheterization is rare. We report a case in which the condition occurred in a 16-year-old girl complaining of dysuria, urgency, frequency, and a residual urine sensation. Cystography revealed a large intravesical filling defect with bladder distension, while sonography and CT demonstrated a large, inhomogeneously enhancing solid mass in the urinary bladder

  8. Surgical treatment of gallbladder polypoid lesions

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    Pejić Miljko A.

    2003-01-01

    Full Text Available INTRODUCTION Polypoid lesions of the gallbladder can be divided into benign and malignant categories. Malignant polypoid lesions include carcinomas of the gallbladder, which is the fifth most common malignancy of the gastrointestinal tract and the most common malignancy of the biliary tract. Benign polypoid lesions of the gallbladder are divided into true tumors and pseudotumors. Pseudotumors account for most of polypoid lesions of the gallbladder, and include polyps, hyperplasia, and other miscellaneous lesions. Adenomas are the most common benign neoplasms of the gallbladder. Cholesterol polyps are the most common pseudotumors of the gallbladder. The polyps can be single or multiple, usually less than 10 mm in size. They have no predilection for any particular gallbladder site, and usually are attached to the gallbladder wall by a delicate, narrow pedicle. No malignant potential has been identified for this type of pseudotumor. Adenomas are the most common benign neoplasms of the gallbladder. They have no predilection site in the gallbladder, and may also be associated with gallstones or cholecystitis. The premalignant nature of adenomas remains controversial. Ultrasonography (US has been demonstrated to be significantly better in detecting polypoid lesions of the gallbladder as compared with computed tomography and cholecystography. A mass fixed to the gallbladder wall of normal thickness, without shadowing, is seen in case of gallbladder polyp. Since gallbladder cancers usually present as polypoid lesions, differentiation between benign polypoid lesion and malignant lesion can be very difficult, even with high-resolution imaging techniques. PATIENTS AND METHODS Retrospectively we have analyzed 38 patients with ultrasonographicaly detected gallbladder polyps during the period from January 1995 to December 2000, who were treated at surgical department of Health Centre in Uzice and at Surgical clinic of Clinical Centre in Nis. We have analyzed

  9. Anaesthesia and subglottic airway obstruction | Bulbulia | Southern ...

    African Journals Online (AJOL)

    Stridor was the presenting feature. A good history and careful assessment will reduce the likelihood of erroneous or delayed diagnosis and will improve patient outcome.This case report highlights the use of target-controlled infusions and jet ventilation (high-pressure source ventilation) in the surgical excision of a subglottic ...

  10. Anesthesia for subglottic stenosis in pediatrics

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    Eid Essam

    2009-01-01

    Full Text Available Any site in the upper airway can get obstructed and cause noisy breathing as well as dyspnea. These include nasal causes such as choanal atresia or nasal stenosis; pharyngeal causes including lingual thyroid; laryngeal causes such as laryngomalacia; tracheobronchial causes such as tracheal stenosis; and subglottic stenosis. Lesions in the oropharynx may cause stertor, while lesions in the laryngotracheal tree will cause stridor. Subglottic stenosis is the third leading cause of congenital stridors in the neonate. Subglottic Stenosis presents challenges to the anesthesiologist. Therefore, It is imperative to perform a detailed history, physical examination, and characterization of the extent and severity of stenosis. Rigid endoscopy is essential for the preoperative planning of any of the surgical procedures that can be used for correction. Choice of operation is dependent on the surgeon′s comfort, postoperative capabilities, and severity of disease. For high-grade stenosis, single-stage laryngotracheal resection or cricotracheal resection are the best options. It has to be borne in mind that the goal of surgery is to allow for an adequate airway for normal activity without the need for tracheostomy. Anesthesia for airway surgery could be conducted safely with either sevofl uraneor propofol-based total intravenous anesthesia.

  11. A bronchoscopic approach to benign subglottic stenosis.

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    Raman, Tuhina; Chatterjee, Kshitij; Alzghoul, Bashar N; Innabi, Ayoub A; Tulunay, Ozlem; Bartter, Thaddeus; Meena, Nikhil K

    2017-01-01

    Subglottic stenosis is an abnormal narrowing of the tracheal lumen at the level of subglottis (the area in between the vocal cords and the cricoid cartilage). It can cause significant symptoms due to severe attenuation of airflow. We describe our experience in alleviating symptoms by addressing the stenosis using fibreoptic bronchoscopic methods. We report all concurrent cases performed between September 2015 and July 2016. We use a combination of balloon dilation, electro-surgery knife to dilate and incise stenotic segments followed by steroid injection to modulate healing. We treated 10 patients in the study period, 8 of which were women. A total of 39 procedures were performed on these patients during this period. Gastro-esophageal reflux was the most common comorbidity associated with stenosis. The majority of the patients required more than 2 therapeutic procedures, but none required more than 4 procedures. There were no complications. Tracheal stenosis and in particular subglottic stenosis is a recurrent process and its management requires extensive collaboration amongst treating specialties. Our technique of steroid injection after dilation of the stenosis was effective in symptom control and decreased the number of repeat procedures.

  12. Estimating Subglottal Pressure from Neck-Surface Acceleration during Normal Voice Production

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    Fryd, Amanda S.; Van Stan, Jarrad H.; Hillman, Robert E.; Mehta, Daryush D.

    2016-01-01

    Purpose: The purpose of this study was to evaluate the potential for estimating subglottal air pressure using a neck-surface accelerometer and to compare the accuracy of predicting subglottal air pressure relative to predicting acoustic sound pressure level (SPL). Method: Indirect estimates of subglottal pressure (P[subscript sg]') were obtained…

  13. Type 1 neovascularization with polypoidal lesions complicating dome shaped macula

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    Naysan, Jonathan; Dansingani, Kunal K; Balaratnasingam, Chandrakumar; Freund, K Bailey

    2015-01-01

    Dome-shaped macula is described as an inward bulge of the macula within a posterior staphyloma in highly myopic eyes. Choroidal neovascularization is a known complication that can cause visual loss in dome-shaped macula. Herein, we describe a patient who presented with features of polypoidal choroidal neovascularization that developed on a background of high myopia with dome-shaped macula.

  14. Characteristics of Fundus Autofluorescence in Active Polypoidal Choroidal Vasculopathy

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    Zafer Öztaş

    2016-08-01

    Full Text Available Objectives: To define characteristic fundus autofluorescence (FAF findings in eyes with active polypoidal choroidal vasculopathy (PCV. Materials and Methods: Thirty-five eyes of 29 patients with active PCV who were diagnosed at Ege University Faculty of Medicine, Department of Ophthalmology, Retina Division between January 2012 and November 2014 were included in the study. All the patients underwent a complete ophthalmological examination including fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, FAF photography, and indocyanine green angiography (ICGA. ICGA was used to diagnose active PCV and identify lesion components. FAF findings were described at the retinal site of the corresponding lesions identified and diagnosed using ICGA. Results: The mean age of the 29 study patients (15 men, 14 women was 64.6±7.5 years (range, 54-82 years. ICGA revealed active PCV in 35 eyes, consisting of polypoid lesions in 11 eyes (31.4%, branching vascular networks (BVN in 10 eyes (28.6%, and a combination of polypoid lesions and BVNs in 14 eyes (40%. On FAF images, 4 different patterns were detected at the corresponding retinal sites of 25 polypoid lesions detected by ICGA: confluent hypoautofluorescence with a hyperautofluorescent ring in 18 eyes (72%, hyperautofluorescence with hypoautofluorescent ring in 2 eyes (8%, confluent hypoautofluorescence in 1 eye (4%, and granular hypoautofluorescence in 1 eye (4%. The remaining 3 eyes (12% demonstrated blocked hypoautofluorescence because of the excessive hemorrhaging in the macula. The FAF images showed the granular hypoautofluorescent FAF pattern in all 24 BVNs (100% consistent with the location of the lesions on ICGA. Conclusion: The typical PCV lesions, polypoid lesions and BVNs had characteristic autofluorescent findings on FAF imaging. Non-invasive, quick, and repeatable FAF imaging can be considered a reliable and helpful diagnostic technique for the diagnosis of

  15. Enhanced dual-phase spiral CT features of polypoid ampullary carcinoma

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    Zeng Mengsu; Yan Fuhua; Zhou Kangrong; Chen Huiming; Chen Gang; Chen Jin

    2001-01-01

    Objective: To understand CT features of polypoid ampullary carcinoma by enhanced dual-phase spiral CT. Methods: 15 cases of polypoid ampullary carcinoma (PAC) confirmed by surgical and pathological results were studied with thin slice enhanced dual-phase spiral CT (including arterial and portal phase scanning)with retrospective analysis, the scanning parameters were 5 mm thickness and 1.0 pitch for arterial phase scanning, and 5 mm thickness and 5 mm space for portal phase scanning. Results: All cases could display an enhanced mass as local filling defect at the site of the duodenal Vater's ampulla during arterial and portal phase scanning, the tumors ranged in size from 1 cm to 5 cm with mean of 2.3 cm, all were accompanied with dilated intrahepatic and common bile duct, enlarged gallbladder and dilated pancreatic duct, except one case which had marked atrophy of the pancreatic body and tail. Conclusion: The thin slices enhanced dual-phase spiral CT could not only accurately define the level of obstruction, but also demonstrate an enhanced mass as direct CT sign of the PAC, which is crucial for diagnosis of the PAC

  16. Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma

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    Yumiko Nakano

    2018-01-01

    Full Text Available Purpose: To report a case of polypoidal choroidal vasculopathy associated with optic disc coloboma. Methods: Case report. Results: A 50-year-old woman presented with optic disc coloboma and retinochoroidal coloboma associated with subretinal hemorrhage and serous retinal detachment (SRD in her left eye. Optical coherence tomography (OCT confirmed SRD at the macula and showed a sharply elevated retinal epithelial detachment at the choroidal excavation. OCT also revealed choroidal cavitation along the temporal side of the optic coloboma. Fluorescein angiography showed hyperfluorescent dye leakage and indocyanine green angiography revealed polypoidal lesions. We diagnosed polypoidal choroidal vasculopathy (PCV. PCV was located at the end of the choroidal cavitation. Her left eye was treated with an intraocular injection of the anti-vascular endothelial growth factor aflibercept (2 mg. Photodynamic therapy was performed using the standard protocol 1 week after the intravitreal application of aflibercept. One month after the combined treatment, OCT showed completely resolved SRD and her symptoms disappeared. Her best-corrected visual acuity remained stable and no recurrence was found during a 12-month follow-up period. Conclusion: PCV associated with optic disc coloboma has not been previously reported. The morphological abnormality of choroidal cavitation and choroidal excavation connecting with optic disc coloboma may contribute to the development of PCV in this case.

  17. Cryopreserved irradiated tracheal homograft reconstruction for subglottic-tracheal stenosis

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    Somyos Kunachak; Yongyudh Vajaradul; Boonchu Kulapaditharom

    1999-01-01

    Subglottic-tracheal stenosis is a common clinical entity. Handling on severe case is often problematic. Various tracheal replacement techniques have been used with varying degree of success and dispute. In this study we worked on cryopreserved irradiated tracheal homograft, of which its use in human has not been reported. The tracheas were harvested from donor cadavers within 24 hours of death in a sterile condition. After 1-2 weeks of preservation at -70 degree C, the grafts were irradiated at 25 kGy, then stored at -70 degree C until used. Four patients, 2 males and 2 females (aged 2-40 years, mean 16 years) with severe subglottic-tracheal stenosis underwent segmental tracheal graft reconstruction using this graft. Immunosuppressant was not given in any patient. The follow up period ranged from 11-1 5 months. Three patients were successfully decapulated, 1 patient developed local infection and dislodgement of intraluminal stent with subsequent restenosis. Postoperative tracheal lumen appeared near normal with histologic evidence of normal respiratory epithelium at the grafted site. In conclusion, cryopreserved irradiated tracheal homograft is a valuable alternative for tracheal transplant or reconstruction, without the need of immunosuppression

  18. schistosomiasis presenting as colonic polypoid masses in a nigerian ...

    African Journals Online (AJOL)

    mansoni infection. CASE PRESENTATION. The patient is a 29 year-old civil servant who presented with recurrent diarrhoea of 2 years duration. Stool is watery, mucoid but not ... 6800/mm3 (Neutrophil-48%, Eosinophil- 1%,. Basophil- 1%, Lymphocyte- 43%, Monocyte- 7%),. Platelets - 319,000/mm3. ESR - 50 mm in the 1st ...

  19. Undersedation is a risk factor for the development of subglottic stenosis in intubated children,

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    Cláudia Schweiger

    Full Text Available Abstract Objective: To analyze the level of sedation in intubated children as a risk factor for the development of subglottic stenosis. Methods: All patients between 30 days and 5 years of age who required endotracheal intubation in the pediatric intensive care unit between 2013 and 2014 were included in this prospective study. They were monitored daily and COMFORT-B scores were obtained. Flexible fiber-optic laryngoscopy was performed within eight hours of extubation, and repeated seven to ten days later if the first examination showed moderate to severe laryngeal injuries. If these lesions persisted and/or if the child developed symptoms in the follow-up period, microlaryngoscopy under general anesthesia was performed to evaluate for subglottic stenosis. Results: The study included 36 children. Incidence of subglottic stenosis was 11.1%. Children with subglottic stenosis had a higher percentage of COMFORT-B scores between 23 and 30 (undersedated than those who did not develop subglottic stenosis (15.8% vs. 3.65%, p = 0.004. Conclusion: Children who developed subglottic stenosis were less sedated than children who did not develop subglottic stenosis.

  20. A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment

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    Shahzad Ahmad

    2014-01-01

    Full Text Available Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45 confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.

  1. [ANCA-negative subglottic laryngeal stenosis in childhood].

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    Wittekindt, C; Lüers, J-C; Drebber, U; Guntinas-Lichius, O; Hüttenbrink, K-B

    2007-10-01

    A 15-year-old female, having developed recurrent infections of the upper airway, hoarseness, dyspnea, and nasal congestion, was referred to our department. There was no history of trauma or intubation. The subglottic space was circularly narrowed. The test for c-ANCA was negative. Chest X-ray and renal function were normal. A tracheotomy was performed; the histology showed infiltrating plasma cells, but no signs of vasculitis or granulomatous inflammation. One year later the patient developed acute renal failure. Biopsy of the kidney confirmed Wegener's disease. The laryngeal stenosis completely resolved after therapy with cyclophosphamide. Juvenile Wegener's granulomatosis is extremely rare; the larynx and trachea seem to be involved more frequently in children than in adults. The positive testing of c-ANCA can support the diagnosis; however, even when c-ANCA do not test positive, the disease can never be excluded. Surgical interventions within the larynx or trachea might only be considered after ineffective therapy with immunosuppressive drugs.

  2. Polypoidal Intestinal Metaplasia and Dysplasia of the External Urethral Meatus

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    Mary Mathew

    2012-01-01

    Full Text Available Urethral mucosa with intestinal metaplasia and dysplasia is a rare occurrence. To date only a single case has been reported in a male with long-standing urethral stricture. We present a 33-year-old female with polypoid intestinal metaplasia and dysplasia of the external urethral meatus in the absence of an inciting factor. Intestinal metaplasia of the urethral mucosa may undergo dysplasia, emphasizing the necessity of a high degree of clinical suspicion and vigilant pathological examination of these lesions.

  3. Resection of pulmonary nodule in a patient with subglottic stenosis under modified spontaneous ventilation anesthesia

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    Shen, Jianfei; Chen, Xuewei; Liang, Lixia

    2017-01-01

    . Here we present a case of pulmonary nodule resection in a patient with subglottic stenosis using uniportal thoracoscopy under spontaneous ventilation anesthesia (SVA). Compared with traditional double lumen endotracheal intubation, we believe this modified technique can significantly reduce airway...

  4. [Subglottic stenosis as the initial manifestation of Wegener's granulomatosis in a teenager. Case report].

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    Cuestas, Giselle; Rodríguez, Verónica; Doormann, Flavia; Pringe, Alejandra; Bellia Munzón, Patricio; Bellia Munzón, Gastón; Ortega, Carlos; Álvarez, Rubén

    2017-04-01

    Wegener's granulomatosis is a necrotizing granulomatous vasculitis of autoimmune origin that primarily affects the upper and lower airways and kidneys. It is very rare in children and adolescents. When started at a young age it is often associated with subglottic stenosis. Subglottic stenosis is a potentially fatal manifestation of Wegener's granulomatosis. Its diagnosis requires a high index of suspicion since it might develop in the absence of other signs of activity. Occasionally, subglottic stenosis may present as the initial manifestation of the disease. Diagnosis is confirmed by endoscopic visualization of the lesion. The treatment is complex, and it often requires repeated interventions due to restenosis. We present a 13-year-old patient with subglottic stenosis secondary to Wegener's granulomatosis. We describe the clinical manifestations, diagnosis and treatment of this rare cause of respiratory distress in the pediatric population. Sociedad Argentina de Pediatría.

  5. Sizeable acquired subglottic cyst in a baby with Williams-Beuren syndrome: association or coincidence?

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    Christoforidis, Athanasios; Tsakalides, Christos; Chatziavramidis, Angelos; Karagianni, Paraskevi; Dimitriadou, Meropi; Konstantinidis, Iordanis

    2013-10-15

    We describe a case of an acquired subglottic cyst presented with persistent stridor and voice hoarsening in a baby diagnosed with Williams-Beuren syndrome that was born premature and required intubation during neonatal period. We also comment on whether this is a coincidence or there can be an association between impaired elastogenesis, a feature of patients with the syndrome and the formation of a subglottic cyst. © 2013 Elsevier B.V. All rights reserved.

  6. Results of radiotherapy for primary subglottic squamous cell carcinoma

    International Nuclear Information System (INIS)

    Paisley, Sonya; Warde, Padraig R.; O'Sullivan, Brian; Waldron, John; Gullane, Patrick J.; Payne, David; Liu, F.-F.; Bayley, Andrew; Ringash, Jolie; Cummings, Bernard J.

    2002-01-01

    Purpose: To retrospectively evaluate the outcome after radical radiotherapy (RT) and surgical salvage and assess the risk of late toxicity for patients with primary subglottic squamous cell carcinoma treated at our center. Methods and Materials: Between 1971 and 1996, 43 patients with primary squamous cell carcinoma of the subglottis (35 men, 8 women) were treated with radical RT. All received megavoltage irradiation, most commonly to a dose of 50-52 Gy in 20 fractions during 4 weeks (39 patients). The median follow-up was 4.2 years. Results: Local control was achieved with RT alone in 24 (56%) of the 43 patients: 7 of 11 with T1, 8 of 12 with T2, 4 of 8 with T3, and 5 of 12 with T4. The 5-year actuarial local relapse-free rate was 52%. Subsequent local control was achieved in 11 of the 13 patients with failed RT and attempted surgical salvage, for an ultimate local control rate of 81.4% (35 of 43). The 5-year overall and cause-specific actuarial survival rate was 50.3% and 66.9%, respectively. No patients developed Grade 3 or 4 late radiation morbidity. Conclusion: These data support the use of primary RT in the treatment of patients with primary squamous cell carcinoma of the subglottis as an appropriate treatment approach providing an option for laryngeal conservation

  7. Polypoid endocervical adenomyoma of the uterus: A case report with MR imaging and pathological analyses

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    Ota, Shunichiro [Department of Obstetrics and Gynecology, Kurume University School of Medicine, Asahi-Machi 67, Kurume, Fukuoka, 830-0011 (Japan)], E-mail: otsir@med.kurume-u.ac.jp; Ushijima, Kimio; Nishio, Shin; Takemoto, Shuji; Fujiyoshi, Naoki; Fukui, Akimasa; Terada, Atsumu; Kamura, Toshiharu [Department of Obstetrics and Gynecology, Kurume University School of Medicine, Asahi-Machi 67, Kurume, Fukuoka, 830-0011 (Japan)

    2008-05-15

    A case of polypoid endocervical adenomyoma in the uterine cervix was encountered in a 56-year-old woman. A well-circumscribed polypoid tumour was observed protruding from the uterine cervix. Based on the findings of MR imaging, the patient was assumed to have an adenoma malignum in the uterine cervix. The tumour was composed of a mixture of endocervical type proliferating glands and fascicles of smooth muscle. No distinct nuclear anaplasia, architectural abnormality, or evidence of destructive stromal invasion was observed. In our case, the tumour was a well-circumscribed polypoid lesion, with no cytologic abnormality, thus suggesting polypoid endocervical adenomyoma. The result of ancillary diagnostic modalities should be interpreted with caution and combined with gross and light microscopic findings.

  8. Polypoid endocervical adenomyoma of the uterus: A case report with MR imaging and pathological analyses

    International Nuclear Information System (INIS)

    Ota, Shunichiro; Ushijima, Kimio; Nishio, Shin; Takemoto, Shuji; Fujiyoshi, Naoki; Fukui, Akimasa; Terada, Atsumu; Kamura, Toshiharu

    2008-01-01

    A case of polypoid endocervical adenomyoma in the uterine cervix was encountered in a 56-year-old woman. A well-circumscribed polypoid tumour was observed protruding from the uterine cervix. Based on the findings of MR imaging, the patient was assumed to have an adenoma malignum in the uterine cervix. The tumour was composed of a mixture of endocervical type proliferating glands and fascicles of smooth muscle. No distinct nuclear anaplasia, architectural abnormality, or evidence of destructive stromal invasion was observed. In our case, the tumour was a well-circumscribed polypoid lesion, with no cytologic abnormality, thus suggesting polypoid endocervical adenomyoma. The result of ancillary diagnostic modalities should be interpreted with caution and combined with gross and light microscopic findings

  9. Focal Endometrial Adenocarcinoma in Atypical Polypoid Adenomyoma of Low Malignant Potential

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    Coskun Salman

    2009-12-01

    This report describes a perimenopausal woman with atypical polypoid adenomyoma of low malignant potential with focal adenocarcinoma on endometrial biopsy who subsequently underwent hysterectomy in which no residual malignant lesion was found.

  10. US or MR Imaging Features of Polypoid Endometriosis: A Case Report

    International Nuclear Information System (INIS)

    Park, Jae Il; Cho, Jae Ho; Kim, Geum Rae; Kim, Mi Jin

    2009-01-01

    Polypoid endometriosis is a rare variant of endometriosis that is pathologically similar to an endometrial polyp. This lesion is frequently mistaken for a solid neoplasm in clinical, radiological and pathological examinations. The clinical and pathological features of the lesion have been well described in the English literature. However, its imaging features have not been reported in the Korean literature. We describe ultrasound and magnetic resonance imaging features of pathologically-confirmed polypoid endometriosis

  11. US or MR Imaging Features of Polypoid Endometriosis: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jae Il; Cho, Jae Ho; Kim, Geum Rae; Kim, Mi Jin [Yeungnam University, Gyeongsan (Korea, Republic of)

    2009-12-15

    Polypoid endometriosis is a rare variant of endometriosis that is pathologically similar to an endometrial polyp. This lesion is frequently mistaken for a solid neoplasm in clinical, radiological and pathological examinations. The clinical and pathological features of the lesion have been well described in the English literature. However, its imaging features have not been reported in the Korean literature. We describe ultrasound and magnetic resonance imaging features of pathologically-confirmed polypoid endometriosis.

  12. Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas

    International Nuclear Information System (INIS)

    Voorham, Quirinus JM; Mulder, Chris JJ; Engeland, Manon van; Meijer, Gerrit A; Steenbergen, Renske DM; Carvalho, Beatriz; Janssen, Jerry; Tijssen, Marianne; Snellenberg, Suzanne; Mongera, Sandra; Grieken, Nicole CT van; Grabsch, Heike; Kliment, Martin; Rembacken, Bjorn J

    2013-01-01

    Nonpolypoid adenomas are a subgroup of colorectal adenomas that have been associated with a more aggressive clinical behaviour compared to their polypoid counterparts. A substantial proportion of nonpolypoid and polypoid adenomas lack APC mutations, APC methylation or chromosomal loss of the APC locus on chromosome 5q, suggesting the involvement of other Wnt-pathway genes. The present study investigated promoter methylation of several Wnt-pathway antagonists in both nonpolypoid and polypoid adenomas. Quantitative methylation-specific PCR (qMSP) was used to evaluate methylation of four Wnt-antagonists, SFRP2, WIF-1, DKK3 and SOX17 in 18 normal colorectal mucosa samples, 9 colorectal cancer cell lines, 18 carcinomas, 44 nonpolypoid and 44 polypoid adenomas. Results were integrated with previously obtained data on APC mutation, methylation and chromosome 5q status from the same samples. Increased methylation of all genes was found in the majority of cell lines, adenomas and carcinomas compared to normal controls. WIF-1 and DKK3 showed a significantly lower level of methylation in nonpolypoid compared to polypoid adenomas (p < 0.01). Combining both adenoma types, a positive trend between APC mutation and both WIF-1 and DKK3 methylation was observed (p < 0.05). Methylation of Wnt-pathway antagonists represents an additional mechanism of constitutive Wnt-pathway activation in colorectal adenomas. Current results further substantiate the existence of partially alternative Wnt-pathway disruption mechanisms in nonpolypoid compared to polypoid adenomas, in line with previous observations

  13. Complete subglottic tracheal stenosis managed with rigid bronchoscopy and T-tube placement

    Directory of Open Access Journals (Sweden)

    Kuruswamy Thurai Prasad

    2016-01-01

    Full Text Available Surgery is the preferred treatment modality for benign tracheal stenosis. Interventional bronchoscopy is used as a bridge to surgery or in instances when surgery is not feasible or has failed. Stenosis in the subglottic trachea is particularly a treatment challenge, in view of its proximity to the vocal cords. Herein, we describe a patient with complete tracheal stenosis in the subglottic region, which developed after prolonged intubation and mechanical ventilation. The patient developed recurrent stenosis despite multiple surgical and endoscopic procedures. We were able to manage the patient successfully with rigid bronchoscopy and Montgomery T-tube placement.

  14. Optical Coherence Tomography Angiography for Assessment of the 3-Dimensional Structures of Polypoidal Choroidal Vasculopathy.

    Science.gov (United States)

    Chi, Yu-Tien; Yang, Chang-Hao; Cheng, Cheng-Kuo

    2017-12-01

    Investigating the quantitative 3-dimensional (3-D) anatomy of polypoidal complex is important for a better understanding of the pathogenesis of polypoidal choroidal vasculopathy (PCV). To quantitatively evaluate the 3-D characteristics of polypoidal structures, branching vascular networks (BVNs), and origin of PCV using optical coherence tomography angiography (OCTA) and multiple image systems. A prospective, observational study was conducted in 47 consecutive Taiwanese patients (47 eyes) from May 21, 2015, to April 30, 2017. All participants were scanned with the Optovue-RTVue-XR-Avanti OCTA system. Patients in whom PCV was identified on OCTA were examined to define characteristics and structures of the original spouting vessels (stalks) from the choroid, polypoidal structures, and BVNs on OCTA. Quantitative analysis of 3-D structures of the polypoidal complex. Among the 47 patients, the mean (SD) patient age was 68.9 (8.0) years, and 28 (59.6%) men were included. Clear images of polypoidal structures could be detected in 17 eyes (36.2%, 22 polypoidal structures), BVNs in 26 eyes (55.3%, 26 tufts of BVNs), and stalks of origin from the choroid in 26 eyes (55.3%, 26 stalks) on the en face plane on OCTA. All polypoidal structures were found at a mean (SD) height of 45.3 (36.1) μm above the retinal pigment epithelium (RPE) reference plane that was preset by the machine, while the BVNs were found at a mean (SD) depth of 28.6 (14.2) μm below the RPE reference plane and the choroidal stalks at 80.4 (24.4) μm below RPE reference plane. The mean (SD) thickness of polypoidal structures was 38.4 (15.5) μm and of BVNs, 60.2 (25.0) μm. The polypoidal structures were all above the Bruch membrane within the dome of the RPE detachment, the choroidal stalks were all in the choroid layer. The BVNs could be either above (up to 18 μm), within, or below (up to 28 μm) the Bruch membrane and were in proximity to the double layers of flattened RPE detachment. These results

  15. Polypoidal Choroidal Vasculopathy: Definition, Pathogenesis, Diagnosis, and Management.

    Science.gov (United States)

    Cheung, Chui Ming Gemmy; Lai, Timothy Y Y; Ruamviboonsuk, Paisan; Chen, Shih-Jen; Chen, Youxin; Freund, K Bailey; Gomi, Fomi; Koh, Adrian H; Lee, Won-Ki; Wong, Tien Yin

    2018-05-01

    Polypoidal choroidal vasculopathy (PCV) is an age-related macular degeneration (AMD) subtype and is seen particularly in Asians. Previous studies have suggested disparity in response to intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents between PCV and typical AMD, and thus, the preferred treatment for PCV has remained unclear. Recent research has provided novel insights into the pathogenesis of PCV, and imaging studies based on OCT suggest that PCV belongs to a spectrum of conditions characterized by pachychoroid, in which disturbance in the choroidal circulation seems to be central to its pathogenesis. Advances in imaging, including enhanced depth imaging, swept-source OCT, en face OCT, and OCT angiography, have facilitated the diagnosis of PCV. Importantly, 2 large, multicenter randomized clinical trials evaluating the safety and efficacy of anti-VEGF monotherapy and combination with photodynamic therapy (PDT) recently reported initial first-year outcomes, providing level I evidence to guide clinicians in choosing the most appropriate therapy for PCV. In this review, we summarize the latest updates in the epidemiologic features, pathogenesis, and advances in imaging and treatment trials, with a focus on the most recent key clinical trials. Finally, we propose current management guidelines and recommendations to help clinicians manage patients with PCV. Remaining gaps in current understanding of PCV, such as significance of polyp closure, high recurrence rate, and heterogeneity within PCV, are highlighted where further research is needed. Copyright © 2018 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  16. Groningen Dilatation Tracheoscope in Treatment of Moderate Subglottic and Tracheal Stenosis

    NARCIS (Netherlands)

    Halmos, Gyorgy; van der Laan, Bernard F. A. M.; Dikkers, Frederik G.

    Objectives: We describe our experience with the Groningen Dilatation Tracheoscope (Karl Storz GmbH & Co, Tuttlingen, Germany) in treating benign subglottic and tracheal stenosis. Methods: We performed a retrospective survey from a medical record analysis of 26 patients with different origins of

  17. Tertiary center experience with primary endoscopic laryngoplasty in pediatric acquired subglottic stenosis and literature review

    Directory of Open Access Journals (Sweden)

    Jaber Alshammari

    2017-03-01

    Conclusion: Our study showed that primary endoscopic management was successful in 82.3% of cases of acquired subglottic stenosis including those with high grade stenosis and long segment of more than 12 mm in terms of the craniocaudal length. CO2 laser was an important tool to convert mature hard stenotic segment into a soft one. The latter yielded to the lateral pressure created by balloon dilatation better.

  18. Subglottal pressure, tracheal airflow, and intrinsic laryngeal muscle activity during rat ultrasound vocalization

    Science.gov (United States)

    2011-01-01

    Vocal production requires complex planning and coordination of respiratory, laryngeal, and vocal tract movements, which are incompletely understood in most mammals. Rats produce a variety of whistles in the ultrasonic range that are of communicative relevance and of importance as a model system, but the sources of acoustic variability were mostly unknown. The goal was to identify sources of fundamental frequency variability. Subglottal pressure, tracheal airflow, and electromyographic (EMG) data from two intrinsic laryngeal muscles were measured during 22-kHz and 50-kHz call production in awake, spontaneously behaving adult male rats. During ultrasound vocalization, subglottal pressure ranged between 0.8 and 1.9 kPa. Pressure differences between call types were not significant. The relation between fundamental frequency and subglottal pressure within call types was inconsistent. Experimental manipulations of subglottal pressure had only small effects on fundamental frequency. Tracheal airflow patterns were also inconsistently associated with frequency. Pressure and flow seem to play a small role in regulation of fundamental frequency. Muscle activity, however, is precisely regulated and very sensitive to alterations, presumably because of effects on resonance properties in the vocal tract. EMG activity of cricothyroid and thyroarytenoid muscle was tonic in calls with slow or no fundamental frequency modulations, like 22-kHz and flat 50-kHz calls. Both muscles showed brief high-amplitude, alternating bursts at rates up to 150 Hz during production of frequency-modulated 50-kHz calls. A differentiated and fine regulation of intrinsic laryngeal muscles is critical for normal ultrasound vocalization. Many features of the laryngeal muscle activation pattern during ultrasound vocalization in rats are shared with other mammals. PMID:21832032

  19. Detection of flat colorectal polyps at screening CT colonography in comparison with conventional polypoid lesions

    Energy Technology Data Exchange (ETDEWEB)

    Sakamoto, Takashi; Urata, Joji [Diagnostic Imaging Center, Saiseikai Kumamoto Hospital, Kumamoto (Japan); Mitsuzaki, Katsuhiko; Matsuda, Katsuhiko; Kawakami, Megumi [Medical Examination Center, Saiseikai Kumamoto Hospital, Kumamoto (Japan); Utsunomiya, Daisuke; Yamamura, Sadahiro; Yamashita, Yasuyuki [Diagnostic Radiology, Faculty of Life Sciences, Kumamoto Univ., Kumamoto (Japan)], e-mail: utsunomi@kumamoto-u.ac.jp

    2012-09-15

    Background: Although the screening of small, flat polyps is clinically important, the role of CT colonography (CTC) screening in their detection has not been thoroughly investigated. Purpose: To evaluate the detection capability and usefulness of CTC in the screening of flat and polypoid lesions by comparing CTC with optic colonoscopy findings as the gold standard. Material and Methods: We evaluated the CTC detection capability for flat colorectal polyps with a flat surface and a height not exceeding 3 mm (n = 42) by comparing to conventional polypoid lesions (n = 418) according to the polyp diameter. Four types of reconstruction images including multiplanar reconstruction, volume rendering, virtual gross pathology, and virtual endoscopic images were used for visual analysis. We compared the abilities of the four reconstructions for polyp visualization. Results: Detection sensitivity for flat polyps was 31.3 %, 44.4 %, and 87.5 % for lesions measuring 2-3 mm, 4-5 mm, and {>=}6 mm, respectively; the corresponding sensitivity for polypoid lesions was 47.6 %, 79.0 %, and 91.7 %. The overall sensitivity for flat lesions (47.6%) was significantly lower than polypoid lesions (64.1%). Virtual endoscopic imaging showed best visualization among the four reconstructions. Colon cancers were detected in eight patients by optic colonoscopy, and CTC detected colon cancers in all eight patients. Conclusion: CTC using 64-row multidetector CT is useful for colon cancer screening to detect colorectal polyps while the detection of small, flat lesions is still challenging.

  20. Subglottic stenosis in granulomatosis with polyangiitis (Wegener's granulomatosis): Report of 4 cases.

    Science.gov (United States)

    Horta-Baas, Gabriel; Hernández-Cabrera, María Fernanda; Catana, Rocío; Pérez-Cristóbal, Mario; Barile-Fabris, Leonor Adriana

    2016-01-01

    Subglottic stenosis (SGS) in granulomatosis with polyangiitis (GPA) may result from active disease or from chronic recurrent inflammation. The objective of the study was to describe the clinical features and treatment of patients with subglottic stenosis. We retrospectively reviewed the medical records of all patients with SGS due to GPA diagnosed at Rheumatology deparment between January 2000 and June 2015. We present 4 cases of SGS at our department during a period of 15 years. The interval between the presentation of the GPA and SGS varied between 2 and 144 months. The leading symptoms of SGS were dyspnoea on exertion and stridor. Three patients presented SGS without evidence of systemic activity. Two patients presented SGS grade i and received tracheal dilatation; two recurred and three needed a tracheostomy due to severe airway-limiting stenosis. SGS presents high morbidity. Even though subglottic dilatation provides symptomatic relief, recurrences may present. Severe airway-limiting stenosis often requires tracheostomy. Copyright © 2015 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.

  1. Perinatal subglottic and hepatic hemangiomas as potential emergencies: effect of radiotherapy

    International Nuclear Information System (INIS)

    Bek, V.; Abrahamova, J.; Koutecky, J.; Kolihova, E.

    1980-01-01

    5 cases are analysed of perinatal hemangiomas in internal localizations representing relative or immediate emergencies. Three cases were subglottic proliferating hemangiomas with threatening suffocation, the other two were large hemangiomas of the liver causing significant hepatomegaly. In 3 children there were also hemangiomas of the skin and'or in the oral cavity seen as important signs in the diagnostic reflections on the nature of the urgent clinical pictures. Moreover one child with subglottic hemangioma suffered from hematological disorders characterizing the Kasabach-Merritt syndrome. In all the children transcutaneous radiotherapy was performed (ranging from 12 Gy in two weeks up to an exceptional dose of 25 Gy over 3 months). This resulted in recession of subjective complaints and, eventually, in complete regression of the irradiated angiomatous lesions, both subglottic and hepatic. The disorders of hemocoagulation also disappeared quickly and completely. At present, i.e., after 3 to 21 years, there are no adverse post-irradiattion changes in any of the patients. Nevertheless, in view of possible post-irradiation effects particularly on the thyroid gland, all the patients continue to be regularly followed up at the respective clinical departments. (author)

  2. Perinatal subglottic and hepatic hemangiomas as potential emergencies: effect of radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Bek, V; Abrahamova, J; Koutecky, J; Kolihova, E [Karlova Univ., Prague (Czechoslovakia). Fakulta Vseobecneho Lekarstvi; Fajstavr, J [Oto-rhino-laryngological Clinic, Pediatric Faculty, Charles University, Prague (Czechoslovakia)

    1980-01-01

    5 cases are analysed of perinatal hemangiomas in internal localizations representing relative or immediate emergencies. Three cases were subglottic proliferating hemangiomas with threatening suffocation, the other two were large hemangiomas of the liver causing significant hepatomegaly. In 3 children there were also hemangiomas of the skin and or in the oral cavity seen as important signs in the diagnostic reflections on the nature of the urgent clinical pictures. Moreover one child with subglottic hemangioma suffered from hematological disorders characterizing the Kasabach-Merritt syndrome. In all the children transcutaneous radiotherapy was performed (ranging from 12 Gy in two weeks up to an exceptional dose of 25 Gy over 3 months). This resulted in recession of subjective complaints and, eventually, in complete regression of the irradiated angiomatous lesions, both subglottic and hepatic. The disorders of hemocoagulation also disappeared quickly and completely. At present, i.e., after 3 to 21 years, there are no adverse post-irradiation changes in any of the patients. Nevertheless, in view of possible post-irradiation effects particularly on the thyroid gland, all the patients continue to be regularly followed up at the respective clinical departments.

  3. Undersedation is a risk factor for the development of subglottic stenosis in intubated children

    Directory of Open Access Journals (Sweden)

    Cláudia Schweiger

    2017-07-01

    Full Text Available Objective: To analyze the level of sedation in intubated children as a risk factor for the development of subglottic stenosis. Methods: All patients between 30 days and 5 years of age who required endotracheal intubation in the pediatric intensive care unit between 2013 and 2014 were included in this prospective study. They were monitored daily and COMFORT-B scores were obtained. Flexible fiber-optic laryngoscopy was performed within eight hours of extubation, and repeated seven to ten days later if the first examination showed moderate to severe laryngeal injuries. If these lesions persisted and/or if the child developed symptoms in the follow-up period, microlaryngoscopy under general anesthesia was performed to evaluate for subglottic stenosis. Results: The study included 36 children. Incidence of subglottic stenosis was 11.1%. Children with subglottic stenosis had a higher percentage of COMFORT-B scores between 23 and 30 (undersedated than those who did not develop subglottic stenosis (15.8% vs. 3.65%, p = 0.004. Conclusion: Children who developed subglottic stenosis were less sedated than children who did not develop subglottic stenosis. Resumo: Objetivo: Analisar o nível de sedação em crianças intubadas como um fator de risco para o desenvolvimento de estenose subglótica (ES. Métodos: Todos os pacientes entre 30 dias e 5 anos de idades que necessitaram de intubação endotraqueal na Unidade de Terapia Intensiva Pediátrica entre 2013 e 2014 foram incluídos neste estudo prospectivo. Eles foram monitorados diariamente e foram obtidos os escores da escala COMFORT-B. Foi feita laringoscopia com tubo flexível de fibra óptica em 8 horas da extubação e repetida 7-10 dias depois, caso o primeiro exame tenha mostrado lesões laríngeas moderadas a graves. Caso essas lesões tenham persistido e/ou caso a criança tenha desenvolvido sintomas no período de acompanhamento, foi feita microlaringoscopia sob anestesia geral para avaliar a ES

  4. Intravitreal bevacizumab associated with photodynamic therapy in a case of polypoidal choroidal vasculopathy associated with choroidal nevus: A case report.

    Science.gov (United States)

    Rangel, Carlos M; Villota, Eva; Fernández-Vega González, Álvaro; Sanchez-Avila, Ronald M

    2017-12-01

    Report the clinical findings and management of a case of polypoidal choroidal vasculopathy associated with choroidal nevus which received combination therapy. Decreased visual acuity in a woman with polypoidal choroidal vasculopathy and choroidal nevus. Polypoidal choroidal vasculopathy and choroidal nevus. The initial visual acuity was 0.5. After the first treatment with photodynamic therapy, exudation and bleeding appeared around the lesion. After this, the patient received 3 doses of intravitreal bevacizumab. After treatment with combination therapy, visual acuity, clinical and imaging findings improved, with no recurrence of exudation and bleeding. Intravitreal bevacizumab as an adjunctive treatment after photodynamic therapy is a good option for patients with polypoidal choroidal vasculopathy associated with choroidal nevus. Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.

  5. Laryngeal Chondrosarcoma as a Rare Cause of Subglottic Stenosis

    Directory of Open Access Journals (Sweden)

    Kerem Kökoğlu

    2014-01-01

    Full Text Available Laryngeal chondrosarcoma (CS is a very rare entity. It is usually seen in 50–80-year olds. It is developed from cricoid cartilage largely. Patients have laryngeal CS complaint of respiratuvar distress, dysphonia, and dysphagia generally. A submucous mass is usually seen in physical examination with an intact mucosa. Distant metastasis is rare in CSs. Main treatment is surgical excision. An 82-year-old patient who has respiratuvar distress is presented in this paper and laryngeal CS is reviewed in the light of the literature.

  6. Ileal polypoid lymphangiectasia bleeding diagnosed and treated by double balloon enteroscopy.

    Science.gov (United States)

    Park, Min Seon; Lee, Beom Jae; Gu, Dae Hoe; Pyo, Jeung-Hui; Kim, Kyeong Jin; Lee, Yun Ho; Joo, Moon Kyung; Park, Jong-Jae; Kim, Jae Seon; Bak, Young-Tae

    2013-12-07

    Intestinal lymphangiectasia is a rare disease characterized by focal or diffuse dilated enteric lymphatics with impaired lymph drainage. It causes protein-losing enteropathy and may lead to gastrointestinal bleeding. Commonly, lymphangiectasia presents as whitish spots or specks. To our knowledge, small bowel bleeding resulting from polypoid intestinal lymphangiectasia has not been reported. Here, we report a rare case of active bleeding from the small bowel caused by polypoid lymphangiectasia with a review of the relevant literature. An 80-year-old woman was hospitalized for melena. Esophagogastroduodenoscopy could not identify the source of bleeding. Subsequent colonoscopy showed fresh bloody material gushing from the small bowel. An abdominal-pelvic contrast-enhanced computed tomography scan did not reveal any abnormal findings. Video capsule endoscopy showed evidence of active and recent bleeding in the ileum. To localize the bleeding site, we performed double balloon enteroscopy by the anal approach. A small, bleeding, polypoid lesion was found in the distal ileum and was successfully removed using endoscopic snare electrocautery. © 2013 Baishideng Publishing Group Co., Limited. All rights reserved.

  7. A Very Rare Cause of Subglottic Stenosis: Non-Malignant Intratracheal Thyroid Tissue

    Directory of Open Access Journals (Sweden)

    Ümit Aydogmus

    2014-08-01

    Full Text Available We present a case of subglottic stenosis associated with benign thyroid tissue involvement due to relapse of multinodular goiter despite surgery 14 years ago.The patient had undergone bilateral subtotal thyroidectomy 14 years ago and the pathology report had been multinodular thyroid tissue at the time. The patient recently presented to an emergency service due to sudden development of respiratory distress and was then directed to our center. Cervical tomography showed bilateral thyroid tissue that narrowed the tracheal diameter by 80% by invading the trachea from the left wall at the level of the thyroid gland. The patient required urgent tracheostomy due to serious respiratory trouble. The trachea was incised vertically about 2.5 cm below the cricoid cartilage. A 2 cm endotracheal lesion with margins that could not be distinguished from the left vocal cord was observed and biopsies were taken from both this lesion and the tissue surrounding the trachea. A Montgomery T-tube extending from the subglottic area to the distal section was placed. Pathology evaluation revealed histopathological findings that matched normal thyroid tissue. Although infrequent, tracheal invasion associated with a thyroid cancer is known to occur. We present a case with postoperative intratracheal relapse due to a benign cause and the emergency treatment.

  8. Intermittent subglottic secretion drainage may cause tracheal damage in patients with few oropharyngeal secretions.

    Science.gov (United States)

    Suys, E; Nieboer, K; Stiers, W; De Regt, J; Huyghens, L; Spapen, H

    2013-12-01

    Injurious prolapse of tracheal mucosa into the suction port has been reported in up to 50% of intubated patients receiving continuous aspiration of subglottic secretions. We investigated whether similar injury could be inflicted by automated intermittent aspiration. Six consecutive patients, intubated with the Mallinckrodt TaperGuard Evac™ endotracheal tube, were studied. A flow sensor was placed between the vacuum regulating system and the mucus collector. Intermittent suctioning was performed at a pressure of -125 mmHg with a 25s interval and duration of 15s. After 24h, a CT scan of the tracheal region was performed. Excessive negative suction pressure, a fast drop in aspiration flow to zero, and important "swinging" movements of secretions in the evacuation line were observed in all patients. Oral instillation of antiseptic mouthwash restored normal aspiration flow and secretion mobility. CT imaging showed marked entrapment of tracheal mucosa into the suction port in all patients. In patients with few oropharyngeal secretions, automated intermittent subglottic aspiration may result in significant and potential harmful invagination of tracheal mucosa into the suction lumen. A critical amount of fluid must be present in the oropharynx to assure adequate and safe aspiration. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Efficacy and toxicity of (chemo)radiotherapy for primary subglottic cancer

    Energy Technology Data Exchange (ETDEWEB)

    Hata, M.; Koike, I.; Odagiri, K.; Minagawa, Y.; Inoue, T. [Yokohama City Univ. Graduate School of Medicine, Yokohama (Japan). Dept. of Radiology; Taguchi, T.; Nishimura, G.; Takahashi, M.; Komatsu, M.; Sano, D. [Yokohama City Univ. Graduate School of Medicine, Yokohama (Japan). Dept. of Otorhinolaryngology

    2013-01-15

    Background and purpose: Primary subglottic cancer is a rare malignancy. We investigated the efficacy and toxicity of radiotherapy for subglottic cancer. Patients and methods: Nineteen patients with primary squamous cell carcinoma of the subglottis received radiotherapy, 14 of whom also underwent chemotherapy. Of the 19 patients, 15 received definitive radiotherapy to the gross tumors with total doses of 70-70.2 Gy in 35-39 fractions, and 4 underwent preoperative radiotherapy with total doses of 37.8-55.8 Gy in 21-31 fractions, followed by total laryngectomy. Results: Of the 19 patients, 5 developed local progression and 2 developed distant metastasis at the median follow-up period of 5 years. The 5-year local control and disease-free rates were 74 and 63%, respectively. Three patients died of tumor progression, and the 5-year overall and disease-free survival rates were 80 and 63%, respectively. Regarding acute toxicities, transient mucositis and dermatitis of grade 3 or lower were observed in all patients, but there were no late toxicities of grade 3 or higher. Conclusion: Radiotherapy is a safe and effective treatment for patients with primary squamous cell carcinoma of the subglottis. The use of chemotherapy together with radiotherapy may enhance treatment efficacy and contribute to larynx preservation through good local control. (orig.)

  10. Flow Glottogram and Subglottal Pressure Relationship in Singers and Untrained Voices.

    Science.gov (United States)

    Sundberg, Johan

    2018-01-01

    This article combines results from three earlier investigations of the glottal voice source during phonation at varying degrees of vocal loudness (1) in five classically trained baritone singers (Sundberg et al., 1999), (2) in 15 female and 14 male untrained voices (Sundberg et al., 2005), and (3) in voices rated as hyperfunctional by an expert panel (Millgård et al., 2015). Voice source data were obtained by inverse filtering. Associated subglottal pressures were estimated from oral pressure during the occlusion for the consonant /p/. Five flow glottogram parameters, (1) maximum flow declination rate (MFDR), (2) peak-to-peak pulse amplitude, (3) level difference between the first and the second harmonics of the voice source, (4) closed quotient, and (5) normalized amplitude quotient, were averaged across the singer subjects and related to associated MFDR values. Strong, quantitative relations, expressed as equations, are found between subglottal pressure and MFDR and between MFDR and each of the other flow glottogram parameters. The values for the untrained voices, as well as those for the voices rated as hyperfunctional, deviate systematically from the values derived from the equations. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  11. Evaluation of the Supraglottic and Subglottic Activities Including Acoustic Assessment of the Opera-Chant Singers.

    Science.gov (United States)

    Petekkaya, Emine; Yücel, Ahmet Hilmi; Sürmelioğlu, Özgür

    2017-12-28

    Opera and chant singers learn to effectively use aerodynamic components by breathing exercises during their education. Aerodynamic components, including subglottic air pressure and airflow, deteriorate in voice disorders. This study aimed to evaluate the changes in aerodynamic parameters and supraglottic structures of men and women with different vocal registers who are in an opera and chant education program. Vocal acoustic characteristics, aerodynamic components, and supraglottic structures were evaluated in 40 opera and chant art branch students. The majority of female students were sopranos, and the male students were baritone or tenor vocalists. The acoustic analyses revealed that the mean fundamental frequency was 152.33 Hz in the males and 218.77 Hz in the females. The estimated mean subglottal pressures were similar in females (14.99 cmH 2 O) and in males (14.48 cmH 2 O). Estimated mean airflow rates were also similar in both groups. The supraglottic structure compression analyses revealed partial anterior-posterior compressions in 2 tenors and 2 sopranos, and false vocal fold compression in 2 sopranos. Opera music is sung in high-pitched sounds. Attempts to sing high-pitched notes and frequently using register transitions overstrain the vocal structures. This intense muscular effort eventually traumatizes the vocal structures and causes supraglottic activity. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  12. Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis.

    Science.gov (United States)

    Muscedere, John; Rewa, Oleksa; McKechnie, Kyle; Jiang, Xuran; Laporta, Denny; Heyland, Daren K

    2011-08-01

    Aspiration of secretions containing bacterial pathogens into the lower respiratory tract is the main cause of ventilator-associated pneumonia. Endotracheal tubes with subglottic secretion drainage can potentially reduce this and, therefore, the incidence of ventilator-associated pneumonia. New evidence on subglottic secretion drainage as a preventive measure for ventilator-associated pneumonia has been recently published and to consider the evidence in totality, we conducted an updated systematic review and meta-analysis. We searched computerized databases, reference lists, and personal files. We included randomized clinical trials of mechanically ventilated patients comparing standard endotracheal tubes to those with subglottic secretion drainage and reporting on the occurrence of ventilator-associated pneumonia. Studies were meta-analyzed for the primary outcome of ventilator-associated pneumonia and secondary clinical outcomes. We identified 13 randomized clinical trials that met the inclusion criteria with a total of 2442 randomized patients. Of the 13 studies, 12 reported a reduction in ventilator-associated pneumonia rates in the subglottic secretion drainage arm; in meta-analysis, the overall risk ratio for ventilator-associated pneumonia was 0.55 (95% confidence interval, 0.46-0.66; p drainage was associated with reduced intensive care unit length of stay (-1.52 days; 95% confidence interval, -2.94 to -0.11; p = .03); decreased duration of mechanically ventilated (-1.08 days; 95% confidence interval, -2.04 to -0.12; p = .03), and increased time to first episode of ventilator-associated pneumonia (2.66 days; 95% confidence interval, 1.06-4.26; p = .001). There was no effect on adverse events or on hospital or intensive care unit mortality. In those at risk for ventilator-associated pneumonia, the use of endotracheal tubes with subglottic secretion drainage is effective for the prevention of ventilator-associated pneumonia and may be associated with reduced

  13. Efficacy of intermittent sub-glottic suctioning in prevention of ventilator-associated pneumonia- A preliminary study of 100 patients

    Directory of Open Access Journals (Sweden)

    M N Vijai

    2016-01-01

    Full Text Available Background and Aims: Oropharyngeal colonisation followed by aspiration of contaminated secretions is the major cause for ventilator-associated pneumonia (VAP. Pooled secretions present in the sub-glottic area above inflated endotracheal tube cuff may be aspirated into the lower airways. It was hypothesised that intermittent suctioning of sub-glottic secretions would prevent VAP. Methods: Group I (n = 50 patients were intubated with HiLo Evac™ endotracheal (ET tube with facility for sub-glottic suctioning, and Group II (n = 50 patients were intubated with HiLo Contour™ ET tube without such facility. In the Group I, sub-glottic suctioning was performed every 2 h. Incidence of VAP, mean ventilator days, Intensive Care Unit (ICU stay and mortality were compared. Qualitative variables were reported as percentages and were compared by Chi-square test or unpaired two-tailed, Fisher′s exact test, as appropriate, to analyse the significance of difference between the two groups. Results: The two groups were similar with respect to demographic characteristics. VAP was seen in 6% of patients in Group I and 22% of patients in Group II (P = 0.021. Both early- and late-onset VAPs were significantly reduced in Group I. Both ventilator days (8.0 vs. 6.45; P = 0.001 and ICU stay (8.33 vs. 6.33; P = 0.001 on the day of onset of VAP were significantly more in the Group I. Total ventilator days were significantly less (6.52 vs. 8.32; P = 0.006 with lower incidence of mortality (36% vs. 48%; P = 0.224 in the Group I. Conclusion: Intermittent sub-glottic suctioning reduces the incidence of VAP including late-onset VAP.

  14. Efficacy of intermittent sub-glottic suctioning in prevention of ventilator-associated pneumonia- A preliminary study of 100 patients.

    Science.gov (United States)

    Vijai, M N; Ravi, Parli R; Setlur, Rangaraj; Vardhan, Harsh

    2016-05-01

    Oropharyngeal colonisation followed by aspiration of contaminated secretions is the major cause for ventilator-associated pneumonia (VAP). Pooled secretions present in the sub-glottic area above inflated endotracheal tube cuff may be aspirated into the lower airways. It was hypothesised that intermittent suctioning of sub-glottic secretions would prevent VAP. Group I (n = 50) patients were intubated with HiLo Evac™ endotracheal (ET) tube with facility for sub-glottic suctioning, and Group II (n = 50) patients were intubated with HiLo Contour™ ET tube without such facility. In the Group I, sub-glottic suctioning was performed every 2 h. Incidence of VAP, mean ventilator days, Intensive Care Unit (ICU) stay and mortality were compared. Qualitative variables were reported as percentages and were compared by Chi-square test or unpaired two-tailed, Fisher's exact test, as appropriate, to analyse the significance of difference between the two groups. The two groups were similar with respect to demographic characteristics. VAP was seen in 6% of patients in Group I and 22% of patients in Group II (P = 0.021). Both early- and late-onset VAPs were significantly reduced in Group I. Both ventilator days (8.0 vs. 6.45; P = 0.001) and ICU stay (8.33 vs. 6.33; P = 0.001) on the day of onset of VAP were significantly more in the Group I. Total ventilator days were significantly less (6.52 vs. 8.32; P = 0.006) with lower incidence of mortality (36% vs. 48%; P = 0.224) in the Group I. Intermittent sub-glottic suctioning reduces the incidence of VAP including late-onset VAP.

  15. Warty gastric cancer with polypoid metastases to the gallbladder and urinary bladder

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    Matsuyama M

    2013-09-01

    Full Text Available Mutsushi Matsuyama,1,2 Kazuo Kato,3 Seiichi Goto,4 Suzuko Moritani,5 Kazuhiro Sentani,6 Makoto Kuroda7 1Clinical Laboratory, Hekinan Municipal Hospital, Hekinan, Aichi, 2Department of Cell Biology and Anatomy, Fujita Health University School of Medicine, Toyoake, Aichi, 3Clinical Laboratory, Rousai Hospital, Nagoya, Aichi, 4Department of Internal Medicine, Hekinan Municipal Hospital, Hekinan, Aichi, 5Department of Advanced Diagnosis, Division of Pathology, National Hospital Organization, Nagoya Medical Center, Nagoya, Aichi, 6Department of Molecular Pathology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, 7Department of Diagnostic Pathology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan Abstract: An 80-year-old man had severe lumbago that was diagnosed as multiple myeloma. He was treated with melphalan, prednisone, and zoledronic acid, with a good response. However, he had severe anemia, and endoscopic examination revealed gastric cancer. He died 3 months later. Autopsy revealed verrucous gastric cancer consisting of numerous polypoid mucosal excrescences that had metastasized to the gallbladder and urinary bladder, showing similar polypoid mucosal lesions. The cancer consisted of poorly differentiated cells (about 85% and signet ring cells (15% in the stomach. The cancerous tissue was not associated with a desmoplastic reaction, and the signet ring cells showed a positive reaction to cytokeratin 7 and regenerating islet-derived family member 4 antibodies. The cancer cells had a propensity to proliferate on the mucosal surface of the stomach, gallbladder, and urinary bladder. Keywords: warty gastric cancer, polypoid metastases, signet ring cells, cytokeratin 7, regenerating islet-derived family member 4

  16. Uterine prolapse with endometrial eversion in association with an unusual diffuse, polypoid, fibrosing perimetritis and parametritis in a cat.

    Science.gov (United States)

    Valentine, Matthew J; Porter, Susan; Chapwanya, Aspinas; Callanan, John J

    2016-01-01

    This case describes a young non-pregnant cat that presented with uterine prolapse in association with an unusual diffuse, polypoid, fibrosing perimetritis and parametritis. Following ovariohysterectomy the cat recovered fully. No intra-abdominal complications were seen on ultrasound examination 3 months postsurgery. At the time of writing, the cat remains healthy. Uterine prolapse in the cat is relatively rare and usually associated with the periparturient period. Inflammatory polypoid perimetritis and parametritis have not previously been documented in cats, and in dogs have only been reported in association with the administration of oestrogenic compounds. The polypoid inflammation affecting the uterus and parametrium may have contributed to increased laxity of the uterine ligaments and predisposed to the development of uterine prolapse.

  17. Giant polypoid gastric heterotopia in the small intestine in a boy: A case report and literature review.

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    Cai, Jing; Yu, Haibo

    2017-01-01

    Heterotopic gastric mucosa has been described at various locations of the body; however, the polyp composed of heterotopic gastric mucosa in the small intestine is rare. A 15-year-old boy visited us for investigation of recurrent episodes of melena. Capsule endoscopy (CE) revealed a polypoid tumor in the ileum, with an active nearby hemorrhage. Contrast-enhanced computed tomography (CECT) showed a tumor in the right quadrant of the abdomen, with a diameter of about 18 × 14 mm. The patient was diagnosed with polypoid gastric heterotopia. We performed an operation to resect the lesion. The patient recovered smoothly after surgery and was discharged on postoperative day 7 and followed up for 3 months. He has not experienced gastrointestinal intestinal (GI) symptoms up to now. Giant polypoid gastric heterotopia in the small intestine is extremely rare, which can express as an occasional finding with or without symptoms. Surgical resection is the preferred therapy when symptoms appear.

  18. Idiopathic polypoidal choroidal vasculopathy in Thai patients with clinical and angiographic choroidal neovascularization

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    Bhoomibunchoo C

    2017-02-01

    Full Text Available Chavakij Bhoomibunchoo,1 Yosanan Yospaiboon,1 Somanus Thoongsuwan,2 Duangnate Rojanaporn,3 Nawat Watanachai,4 Pichai Jirarattanasopa,5 Nattapon Wongcumchang,6 Atchara Amphornphruet,7 Sritatath Vongkulsiri,8 Eakkachai Arayangkoon9 1Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 2Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 3Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 4Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 5Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, Songkhla, 6Department of Ophthalmology, Faculty of Medicine, Thammasat University, Pathum Thani, 7Department of Ophthalmology, Rajavithi Hospital, Bangkok, 8Department of Ophthalmology, Phramongkutklao Hospital, Bangkok, 9Department of Ophthalmology, Mettapracharak Hospital, Nakhon Pathom, Thailand Objective: This study aimed to study the prevalence and characteristics of idiopathic polypoidal choroidal vasculopathy (IPCV in Thai patients with clinical and angiographic choroidal neovascularization (CNV.Patients and methods: A consecutive case study of 140 patients presenting with CNV was conducted in nine large referral eye centers throughout Thailand. The demographic data, fundus photographs, fundus fluorescein angiography and indocyanine green angiography of the patients were analyzed.Results: Of 129 patients with clinical and angiographic CNV, IPCV was diagnosed in 100 patients (77.52%, idiopathic CNVs in 16 patients (12.40% and age-related macular degeneration (AMD in 12 patients (9.30%. Of the 107 eyes with IPCV, 90 eyes (84.11% had both branching venous networks (BVNs and polypoidal lesions. Most IPCV patients (93% had unilateral involvement and were at a younger age than AMD patients. In all, 79 eyes (73.83% had lesions found in the macular area, 14 eyes (13.08% in the

  19. Serial office-based steroid injections for treatment of idiopathic subglottic stenosis.

    Science.gov (United States)

    Hoffman, Matthew R; Coughlin, Adam R; Dailey, Seth H

    2017-11-01

    Current treatment options for idiopathic subglottic stenosis include endoscopic interventions, resection, and tracheotomy. Recently, serial office-based steroid injections were proposed as an alternative that may stabilize or induce regression of airway stenosis without the need for repeated operations. Procedure completion rate, pain, complications, effect on stenosis, time since the last operation, and limitations have not been described. Retrospective case series. Retrospective series of 19 patients undergoing serial office-based steroid injection for idiopathic subglottic stenosis. Outcome measures included completion rate, procedure-related pain scores, complications, percentage of airway stenosis, and time since the last operative intervention. Procedure completion rate was 98.8%. Average pain score during the procedure was 2.3 ± 1.7 on a 10-point scale. There were no immediate complications. One patient underwent awake tracheotomy 8 days after her second injection and was later decannulated. Average stenosis decreased from 35% ± 15% to 25% ± 15% (n = 16; P = .086) over the first of three injections and 40% ± 15% to 25% ± 10% to 20% ± 10% (n = 8; P = .002) for those patients completing two sets of three injections. Fourteen of 17 patients undergoing at least three injections have not returned to the operating room since the first injection. Office-based steroid injection represents a promising new treatment pathway for a disease that requires long-term management, offering a purely pharmacologic approach to a disorder that has traditionally been approached from a mechanical perspective. It is safe, well tolerated, and effective. Furthermore, it may help patients and physicians avoid repeated trips to the operating room and the associated risks. 4. Laryngoscope, 127:2475-2481, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  20. Aquamous cell carcinomas of the lung which presented as numerous polypoid nodules in the tracheobronchial tree: A case report

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    Lee, Hyun Gyu; Choi, Yo Won; Yoon, Hyun Jung; Paik, Seung Sam [Hanyang University Hospital, Hanyang University College of Medicine, Seoul (Korea, Republic of)

    2017-03-15

    We report a case of squamous cell carcinomas of the lung, which presented as numerous polypoid nodules in the tracheobronchial tree. They occurred at two years and 7 months after resection of squamous cell carcinoma, which presented as a lung nodule in the left lower lobe, and at 7 months after resection of tracheal squamous cell carcinoma.

  1. Aquamous cell carcinomas of the lung which presented as numerous polypoid nodules in the tracheobronchial tree: A case report

    International Nuclear Information System (INIS)

    Lee, Hyun Gyu; Choi, Yo Won; Yoon, Hyun Jung; Paik, Seung Sam

    2017-01-01

    We report a case of squamous cell carcinomas of the lung, which presented as numerous polypoid nodules in the tracheobronchial tree. They occurred at two years and 7 months after resection of squamous cell carcinoma, which presented as a lung nodule in the left lower lobe, and at 7 months after resection of tracheal squamous cell carcinoma

  2. Prevention of ventilator-associated pneumonia through aspiration of subglottic secretions: a systematic review and meta-analysis.

    Science.gov (United States)

    Leasure, A Renee; Stirlen, Joan; Lu, Shu Hua

    2012-01-01

    Ventilator-associated pneumonia (VAP) is a subset of hospital-acquired pneumonias and is a serious, sometimes fatal, complication in patients who need mechanical ventilation. In addition, pay-for-performance initiative has placed increased emphasis on preventing nosocomial infections including VAP. Facilities may not be reimbursed for costs associated with prevalence infections. This article presents a review and meta-analysis of the prevention of VAP through the aspiration of subglottic secretion.

  3. Surgical solution of subglottic stenosis graded III by Cotton in a child

    International Nuclear Information System (INIS)

    Sebova, I.; Sittel, Ch.

    2017-01-01

    The solution of laryngotracheal (LT) stenoses of a higher degree in children is a serious problem. Sometimes they arise due to iatrogenic trauma caused by long-term intubation through surface pressure of the intubation tube in the ring cartilage area. 50% of inborn LT stenoses are connected with systematic congenital developmental defects. The case history describes a case of a boy 5.5 years old born prematurely as the first one of twins and immediately after birth he had to be intubed due to the breathing problems. His twin had exited. The patient spent 41 days on pulmonary ventilation, survived sepsis, newborn jaundice, anaemia, then bronchopulmonary dysplasia and central hypotonic syndrome were found. The first attempt with extubation after the treatment was unsuccessful. Besides the pulmonary findings subglottic stenosis of insignificant grade was stated and the 3-month-old child underwent planned tracheostomy. Subsequently the child went through surgical treatment of retinopathy in the prematured and scrotal hernia on both sides. In the course of several years he suffered from recurrence of acute respiratory tract inflammation, incl. bronchopneumonia, the respiratory tract was colonised by pathogenic chronic microflora. The child was repeatedly examined with the endoscope, granulations in the area of tracheostomy were removed. Though the finding in the larynx - persisting narrowing - has been considered unimportant for several years, in spite of this some further unsuccessful attempts with decannulation of the child followed. In the meantime the patient was followed up as a long-time cannula patient at DORLK LF UK and DFNsP in Bratislava, his tracheostomy cannulas were exchanged. At the age of 5 surgical treatment of subglottic stenosis graded III by Cotton in the child was proposed. In February 2016 partial cricotracheal resection (PCTR) was performed applying LT Mold at the Clinic for Ear, Nose and Throat Disorders, Plastic Surgery at the City Hospital in

  4. Clinical relevance of aberrant polypoid nodule scar after endoscopic submucosal dissection

    Science.gov (United States)

    Arantes, Vitor; Uedo, Noriya; Pedrosa, Moises Salgado; Tomita, Yasuhiko

    2016-01-01

    AIM To describe a series of patients with aberrant polypoid nodule scar developed after gastric endoscopic submucosal dissection (ESD), and to discuss its pathogenesis and clinical management. METHODS We reviewed retrospectively the endoscopic database of two academic institutions located in Brazil and Japan and searched for all patients that underwent ESD to manage gastric neoplasms from 2003 to 2015. The criteria for admission in the study were: (1) successful en bloc ESD procedure with R0 and curative resection confirmed histologically; (2) postoperative endoscopic examination with identification of a polypoid nodule scar (PNS) at ESD scar; (3) biopsies of the PNS with hyperplastic or regenerative tissue, reviewed by two independent experienced gastrointestinal pathologists, one from each Institution. Data were examined for patient demographics, Helicobacter pylori status, precise neoplastic lesion location in the stomach, tumor size, histopathological assessment of the ESD specimen, and postoperative information including medical management, endoscopic and histological findings, and clinical outcome. RESULTS A total of 14 patients (10 men/4 women) fulfilled the inclusion criteria and were enrolled in this study. One center contributed with 8 cases out of 60 patients (13.3%) from 2008 to 2015. The second center contributed with 6 cases (1.7%) out of 343 patients from 2003 to 2015. Postoperative endoscopic follow-up revealed similar findings in all patients: A protruded polypoid appearing nodule situated in the center of the ESD scar surrounded by convergence of folds. Biopsies samples were taken from PNS, and histological assessment revealed in all cases regenerative and hyperplastic tissue, without recurrent tumor or dysplasia. Primary neoplastic lesions were located in the antrum in 13 patients and in the angle in one patient. PNS did not develop in any patient after ESD undertaken for tumors located in the corpus, fundus or cardia. All patients have been

  5. Primary Signet-Ring Carcinoma in the Bladder Presenting as a Hypervascular Luminal Polypoid Mass

    International Nuclear Information System (INIS)

    Jeong, Min Sun; Choi, Seung A; Jung, Yoon Young; Cho, Young Kwon; Lee, Won Mi; Lee, Seung Wook

    2012-01-01

    Primary signet-ring carcinoma is a very aggressive and rare variant of a primary urinary bladder cancer, accounting for less than 1% of cases. We reported on a 76-year-old patient with primary signet-ring carcinoma who occurred metastatic lymphadenopathy with extranodal invasion causing intraluminal tumor thrombi in the adjacent vein, and pulmonary metastasis over the course of three months. We demonstrated the computed tomography findings of primary signet-ring carcinoma of the bladder and correlated the imaging findings with the pathologic features. We reviewed the distinguishing imaging findings of the primary signet-ring carcinoma compared with urothelial cell carcinoma, the most common subtype of the bladder cancer.

  6. Chorioretinal anastomosis after photodynamic therapy for polypoidal choroidal vasculopathy: CRA after PDT for PCV.

    Science.gov (United States)

    Yodoi, Yuko; Tsujikawa, Akitaka; Otani, Atsushi; Aikawa, Hiroko; Yoshimura, Nagahisa

    2008-08-01

    An 80-year-old woman was treated with photodynamic therapy (PDT) to the left eye for polypoidal choroidal vasculopathy (PCV). About 3 months after PDT, her left eye developed a chorioretinal anastomosis with severe atrophy of the retinal pigment epithelium in the macula; visual acuity in this eye was 20/1000. She received a second session of PDT, plus an intravitreal injection of triamcinolone acetonide. About 3 months after the second treatment, the chorioretinal anastomosis was enlarged and the retinal vessels involved in the anastomosis were more dilated. About 1 year after the first PDT, visual acuity in the left eye had stabilized at 20/400. Development of a chorioretinal anastomosis is a distinct possibility following PDT in eyes with PCV, and can lead to poor visual recovery.

  7. Balloon Dilatation of Pediatric Subglottic Laryngeal Stenosis during the Artificial Apneic Pause: Experience in 5 Children

    Directory of Open Access Journals (Sweden)

    J. Lisý

    2014-01-01

    Full Text Available Introduction. Balloon dilatation is a method of choice for treatment of laryngeal stenosis in children. The aim of procedure in apneic pause is to avoid new insertion of tracheostomy cannula. Patients and Methods. The authors performed balloon dilatation of subglottic laryngeal strictures (SGS in 5 children (3 girls and 2 boys without tracheotomy. Two of them with traumatic and inflammatory SGS had a tracheal cannula removed in the past. The other 3 children with postintubation SGS had never had a tracheostomy before. The need for tracheostomy due to worsening stridor was imminent for all of them. Results. The total of seven laryngeal dilatations by balloon esophagoplasty catheter in apneic pause was performed in the 5 children. The procedure averted the need for tracheostomy placement in 4 of them (80%. Failure of dilatation in girl with traumatic stenosis and concomitant severe obstructive lung disease led to repeated tracheostomy. Conclusion. Balloon dilatation of laryngeal stricture could be done in the absence of tracheostomy in apneic pause. Dilatation averted threatening tracheostomy in all except one case. Early complication after the procedure seems to be a negative prognostic factor for the outcome of balloon dilatation.

  8. Frequent β-catenin gene mutations in atypical polypoid adenomyoma of the uterus.

    Science.gov (United States)

    Takahashi, Hiroyuki; Yoshida, Tsutomu; Matsumoto, Toshihide; Kameda, Yoichi; Takano, Yasuo; Tazo, Yuki; Inoue, Hisako; Saegusa, Makoto

    2014-01-01

    Atypical polypoid adenomyoma (APA) is an uncommon polypoid lesion of the uterus. To clarify the mechanism of its histogenesis, we examined the functional role of β-catenin, with reference to expression of p21(waf1), cyclin D1, cyclin E, CD10, and α-smooth muscle actin (SMA), as well as cell proliferation, in 7 lesions. In the epithelial components, expression of nuclear β-catenin, p21(waf1), and cyclin D1 was increased in a stepwise fashion from normal tissue through complex atypical hyperplasia and adenomyoma to APA lesions, particularly in squamous morular areas, whereas cell proliferation, as well as cyclin E expression, was significantly decreased in the latter. Similar findings were evident in the stromal lesions, with the exception of a case of nuclear β-catenin. In addition, coexpression of CD10 and α-SMA markers was observed in the stromal components in 3 APA cases, in line with the results of normal secretory endometrial and adenomyoma samples, suggesting that cells progress to myofibromatous cells in response to differentiation-promoting events. Finally, β-catenin gene (CTNNB1) mutations were detected in all APA cases, the single nucleotide substitutions being in the epithelial but not the stromal components. These findings suggest that activation of β-catenin signaling, probably secondary to the gene abnormalities, plays an important role in the formation of the complex epithelial architecture in APAs, leading to inhibition of cell proliferation through overexpression of p21(waf1). In contrast, changes in the stromal cell phenotype may occur through a shift from CD10 to α-SMA immunopositivity, independent of CTNNB1 status. © 2013.

  9. A randomized clinical trial of continuous aspiration of subglottic secretions in cardiac surgery patients.

    Science.gov (United States)

    Kollef, M H; Skubas, N J; Sundt, T M

    1999-11-01

    To determine whether the application of continuous aspiration of subglottic secretions (CASS) is associated with a decreased incidence of ventilator-associated pneumonia (VAP). Prospective clinical trial. Cardiothoracic ICU (CTICU) of Barnes-Jewish Hospital, St. Louis, a university-affiliated teaching hospital. Three hundred forty-three patients undergoing cardiac surgery and requiring mechanical ventilation in the CTICU. Patients were assigned to receive either CASS, using a specially designed endotracheal tube (Hi-Lo Evac; Mallinckrodt Inc; Athlone, Ireland), or routine postoperative medical care without CASS. One hundred sixty patients were assigned to receive CASS, and 183 were assigned to receive routine postoperative medical care without CASS. The two groups were similar at the time of randomization with regard to demographic characteristics, surgical procedures performed, and severity of illness. Risk factors for the development of VAP were also similar during the study period for both treatment groups. VAP was seen in 8 patients (5.0%) receiving CASS and in 15 patients (8. 2%) receiving routine postoperative medical care without CASS (relative risk, 0.61%; 95% confidence interval, 0.27 to 1.40; p = 0. 238). Episodes of VAP occurred statistically later among patients receiving CASS ([mean +/- SD] 5.6 +/- 2.3 days) than among patients who did not receive CASS (2.9 +/- 1.2 days); (p = 0.006). No statistically significant differences for hospital mortality, overall duration of mechanical ventilation, lengths of stay in the hospital or CTICU, or acquired organ system derangements were found between the two treatment groups. No complications related to CASS were observed in the intervention group. Our findings suggest that CASS can be safely administered to patients undergoing cardiac surgery. The occurrence of VAP can be significantly delayed among patients undergoing cardiac surgery using this simple-to-apply technique.

  10. Squamous cell carcinoma of the larynx with subglottic extension: is larynx preservation possible

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    Levy, A.; Blanchard, P.; Lusinchi, A.; Daly-Schveitzer, N.; Tao, Y. [Gustave Roussy, Department of Radiotherapy, Villejuif (France); Temam, S.; Maison, M.M.; Janot, F.; Mirghani, H. [Gustave Roussy, Department of Otorhinolaryngology - Head and Neck Surgery, Villejuif (France); Bidault, F. [Gustave Roussy, Department of Diagnostic Radiology, Villejuif (France); Guigay, J. [Gustave Roussy, Department of Medical Oncology, Villejuif (France); Bourhis, J. [Gustave Roussy, Department of Radiotherapy, Villejuif (France); University Hospital Lausanne, Department of Radiation Oncology, Lausanne (Switzerland)

    2014-07-15

    Squamous cell carcinoma of larynx with subglottic extension (sSCC) is a rare location described to carry a poor prognosis. The aim of this study was to analyze outcomes and feasibility of larynx preservation in sSCC patients. Between 1996 and 2012, 197 patients with sSCC were treated at our institution and included in the analysis. Stage III-IV tumors accounted for 76 %. Patients received surgery (62 %), radiotherapy (RT) (18 %), or induction chemotherapy (CT) (20 %) as front-line therapy. The 5-year actuarial overall survival (OS), locoregional control (LRC), and distant control rate were 59 % (95 % CI 51-68), 83 % (95 % CI 77-89), and 88 % (95 % CI 83-93), respectively, with a median follow-up of 54.4 months. There was no difference in OS and LRC according to front-line treatments or between primary subglottic cancer and glottosupraglottic cancers with subglottic extension. In the multivariate analysis, age > 60 years and positive N stage were the only predictors for OS (HR 2, 95 % CI 1.2-3.6; HR1.9, 95 % CI 1-3.5, respectively). A lower LRC was observed for T3 patients receiving a larynx preservation protocol as compared with those receiving a front-line surgery (HR 14.1, 95 % CI 2.5-136.7; p = 0.02); however, no difference of ultimate LRC was observed according to the first therapy when including T3 patients who underwent salvage laryngectomy (p = 0.6). In patients receiving a larynx preservation protocol, the 5-year larynx-preservation rate was 55 % (95 % CI 43-68), with 36 % in T3 patients. The 5-year larynx preservation rate was 81 % (95 % CI 65-96) and 35 % (95 % CI 20-51) for patients who received RT or induction CT as a front-line treatment, respectively. Outcomes of sSCC are comparable with other laryngeal cancers when managed with modern therapeutic options. Larynx-preservation protocols could be a suitable option in T1-T2 (RT or chemo-RT) and selected T3 sSCC patients (induction CT). (orig.) [German] Plattenepithelkarzinome des Larynx mit

  11. Characteristic appearances of fundus autofluorescence in treatment-naive and active polypoidal choroidal vasculopathy: a retrospective study of 170 patients.

    Science.gov (United States)

    Zhao, Xinyu; Xia, Song; Chen, Youxin

    2018-06-01

    To investigate the characteristic appearances of fundus autofluorescence (FAF) in patients with treatment-naive and active polypoidal choroidal vasculopathy (PCV). Cases with the diagnosis of treatment-naive and active PCV from November 2012 to May 2017 at Peking Union Medical College Hospital were retrospectively reviewed. All patients underwent comprehensive ophthalmologic examination. Autofluorescence (AF) findings were described at the retinal sites of the corresponding lesions identified and diagnosed using indocyanine green angiography and spectral-domain optical coherence tomography. One hundred seventy patients with 192 affected eyes were included. The logMAR BCVA of the patients were 0.53 ± 0.28. The six AF patterns of 243 polypoidal lesions were confluent hypo-AF with hyper-AF ring (49.8%), confluent hypo-AF (22.6%), hyper-AF with hypo-AF ring (3.7%), granular hypo-AF (7.0%), blocked hypo-AF due to hemorrhage (8.6%), and polyps without apparent AF changes (8.2%). For 146 branching vascular networks (BVNs), 97.3% were granular hypo-AF, and others were blocked hypo-AF due to hemorrhage. In eyes with treatment-naive and active PCV, the polypoidal lesions and BVNs induce characteristic FAF changes. FAF images provide reliable adjunct reference for the diagnosis of PCV.

  12. Subglottic stenosis in short-statured children: a case for further investigation of airway symptoms in patients with skeletal dysplasias.

    Science.gov (United States)

    Lee, Jonathan H; Ellison, Jay W; Schears, Gregory J; Thompson, Dana M

    2006-01-01

    Clinical evaluation of children with skeletal dysplasias is often concentrated on morphologic and radiographic assessments, but many of these patients also have disease processes of the ear, nose, and throat. We report a case of an 11-month-old girl with an unknown short-limbed dwarfism, similar to acromicric dysplasia, with grade II subglottic stenosis. Laryngotracheoplasty with anterior autologous costal cartilage graft and posterior cricoid split was performed at age 13 months, with subsequent improvement of her airway status. In cases of children with skeletal dysplasias and obstructive airway symptoms, formal otolaryngologic evaluation is warranted for definitive diagnosis and treatment.

  13. Valsalva-Related Subretinal Hemorrhage as a Presenting Symptom of Polypoidal Choroidal Vasculopathy

    Directory of Open Access Journals (Sweden)

    Yousif Subhi

    2017-01-01

    Full Text Available Purpose. To describe a case of Valsalva-related subretinal hemorrhage as a presenting symptom of polypoidal choroidal vasculopathy (PCV. The patient refrained from treatment against our best advice, and thus this is also a rare case of the natural course of an untreated PCV. Methods. Case report. Results. A 66-year-old female with a respiratory infection coughed intensely until exhaustion, after which she developed visual symptoms on the right eye. Primary care ophthalmologist examined the patient on the same day of the onset of symptoms and referred her to our tertiary medical retinal service for detailed retinal diagnosis including fluorescein and indocyanine green angiography. The right eye had a large subretinal hemorrhage and pigment epithelium detachment in the lower temporal arcade with foveal involvement. Against our best advice, the patient refused treatment. In the following 9 months, the BCVA decreased from 68 to 55 ETDRS letters, the subretinal hemorrhage almost regressed, pigment epithelium detachments persisted, and macular edema, intraretinal cysts, and subretinal fibrosis developed. Conclusions. Although classic Valsalva retinopathy with preretinal hemorrhage in most cases can be managed by careful observation and no treatment, this case demonstrates that Valsalva-related subretinal hemorrhage needs different attention and approach.

  14. The association of elastin gene variants with two angiographic subtypes of polypoidal choroidal vasculopathy.

    Directory of Open Access Journals (Sweden)

    Suiho Yanagisawa

    Full Text Available To compare the association of elastin (ELN gene variants between two different angiographic phenotypes of polypoidal choroidal vasculopathy (PCV.We included 411 treatment-naïve PCV patients and 350 controls in the present study. PCV was classified into two phenotypes (152 Type 1 and 259 Type 2 according to the presence or absence of feeding vessels found in indocyanine-green angiography. Single nucleotide polymorphisms (SNPs in the ELN region including rs868005, rs884843, rs2301995, rs13239907 and rs2856728 were genotyped using TaqMan Genotyping Assays.In the allelic association analyses, rs868005 showed the strongest association with Type 2 PCV (allelic odds ratio 1.56; p = 7.4x10(-6, while no SNP was significantly associated with Type 1 PCV. Genotype association analyses revealed the significant association of rs868005 with Type 2 PCV in log additive model and predominant model (odds ratio 1.75; p = 1.5x10(-6 and odds ratio 1.60; p = 0.0044, respectively, but not with Type 1 PCV. These findings were further corroborated by another control group in the literature.There may be significantly different associations in genetic variants of elastin between two angiographic phenotypes of PCV.

  15. Prevalence and risk factors of gallbladder polypoid lesions in Chinese petrochemical employees.

    Science.gov (United States)

    Mao, Yu-Shan; Mai, Yi-Feng; Li, Fu-Jun; Zhang, Yan-Ming; Hu, Ke-Min; Hong, Zhong-Li; Zhu, Zhong-Wei

    2013-07-21

    To investigate the prevalence and risk factors of polypoid lesions of the gallbladder (PLGs) in petrochemical employees in Ningbo, Zhejiang Province, China. All active and retired employees aged 20-90 years (n = 11098) of a refinery and chemical plant in eastern China were requested to participate in a health survey. The participants were subjected to interview, physical examination, laboratory assessments and ultrasonography. All the participants were invited to have a physical examination after a face-to-face interview. Fasting blood samples were obtained from the antecubital vein, and the samples were used for the analysis of biochemical values. Abdominal ultrasonography was conducted. A total of 10461 (7331 men and 3130 women) current and former petrochemical employees attended for screening. The overall prevalence of post-cholecystectomy, gallstones and PLGs was 0.9%, 5.2% and 7.4%, respectively. Compared with the increased prevalence of either gallstones or post-cholecystectomy in older persons, PLGs were more common in the middle-aged, peaking in those aged 40-59 years. Excluding the patients with gallstones, gallstones mixed with PLGs, or those who had undergone cholecystectomy, in the remaining 9828 participants, the prevalence of PLGs in men (8.9%) was significantly higher than that in women (5.5%, P employees. Male gender, HBsAg positivity, and middle age are risk factors for developing PLGs.

  16. Characteristics of polypoid lesions in patients undergoing microsurgery of the larynx

    Directory of Open Access Journals (Sweden)

    Ido Filho, Jorge Massaaki

    2014-01-01

    Full Text Available Introduction: Dysphonia is the main symptom of lesions that affect the vocal tract. Many of those lesions may require surgical treatment. Polyps are one of the most common forms of vocal cord lesions and the most prevalent indication for laryngeal microsurgery. There are different types of polyps, and their different characteristics can indicate different prognosis and treatments. Aim: To conduct a comparative study of polypoid lesions (angiomatous and gelatinous in patients undergoing laryngeal microsurgery via an electronic protocol. Method: We prospectively evaluated 93 patients diagnosed with vocal fold polyps; the polyps were classified as angiomatous or gelatinous. Results: In total, 93 patients undergoing laryngeal microsurgery were diagnosed with vocal fold polyps. Of these, 63 (64.74% had angiomatous and 30 (32.26% gelatinous polyps. Most patients with angiomatous polyps were men; their polyps were frequently of medium size, positioned in the middle third of the vocal fold, and accompanied by minimal structural alterations (MSA. In contrast, the majority of patients with gelatinous polyps were women; their polyps were smaller, positioned in the middle and posterior third of the vocal fold, and were not accompanied by MSA. Both types of polyps were more frequently located on the right vocal fold. Conclusion: Angiomatous polyps were more frequently encountered than gelatinous polyps. In addition, correlations between polyp type and sex, polyp size, position, location, and the presence of MSA were observed. Different surgical techniques were used, but the postoperative results were similar and satisfactory after speech therapy.

  17. Magnitude of Neck-Surface Vibration as an Estimate of Subglottal Pressure during Modulations of Vocal Effort and Intensity in Healthy Speakers

    Science.gov (United States)

    McKenna, Victoria S.; Llico, Andres F.; Mehta, Daryush D.; Perkell, Joseph S.; Stepp, Cara E.

    2017-01-01

    Purpose: This study examined the relationship between the magnitude of neck-surface vibration (NSV[subscript Mag]; transduced with an accelerometer) and intraoral estimates of subglottal pressure (P'[subscript sg]) during variations in vocal effort at 3 intensity levels. Method: Twelve vocally healthy adults produced strings of /p?/ syllables in 3…

  18. Short-term efficacy of intravitreal conbercept in treatment-naive patients with polypoidal choroidal vasculopathy

    Directory of Open Access Journals (Sweden)

    Peng Y

    2018-02-01

    Full Text Available Yuting Peng, Xiongze Zhang, Miaoling Li, Bing Liu, Lan Mi, Chengguo Zuo, Feng Wen State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China Introduction: To evaluate the functional and morphological outcomes of intravitreal conbercept monotherapy in patients with polypoidal choroidal vasculopathy (PCV. Materials and methods: In this retrospective, observational case series study, we reviewed medical records of 48 eyes (48 patients with naive PCV that were treated with a series of 3 monthly intravitreal injections of 0.5 mg of conbercept followed by as-needed injections (3+pro re nata. All patients completed at least 6 months of monthly follow-up. Changes in the best-corrected visual acuity, optical coherence tomography, and indocyanine green angiography were retrospectively evaluated. Results: At 6 months, the mean best-corrected visual acuity significantly improved from 0.89±0.35 (20/160 in Snellen equivalent at baseline to 0.58±0.26 (Snellen equivalent of 20/80; P<0.001, and 60.42% (29/48 of eyes had an improvement of three lines of vision; the mean central retinal thickness significantly decreased from 333.56±171.04 µm at baseline to 187.65±54.46 µm (P<0.001, and 93.75% (45/48 achieved a dry macula. At 3 months, 6 of 32 eyes (18.75% showed partial regression of branching vascular network, 14 of 32 (43.75% patients showed complete resolution of polyps. The mean number of injections was 3.4±0.9 through 6 months. No conbercept-related systemic or ocular adverse effects were observed. Conclusion: Intravitreal injection of conbercept using “3+pro re nata” regimen significantly improved visual acuity and anatomical outcomes in treatment-naive patients with PCV. Keywords: conbercept, intravitreal injection, PCV, short-term efficacy, “3+PRN”

  19. Immunohistochemical characteristics of atypical polypoid adenomyoma with special reference to h-caldesmon.

    Science.gov (United States)

    Horita, Ayako; Kurata, Atsushi; Maeda, Daichi; Fukayama, Masashi; Sakamoto, Atsuhiko

    2011-01-01

    Atypical polypoid adenomyoma (APA) is a relatively rare benign uterine tumor, histologically characterized by proliferation of irregular endometrioid glands accompanied by stromal cells of smooth muscle origin. As the epithelial components of APA usually show cytological atypia, a differential diagnosis between this tumor and endometrioid carcinoma invading myometrium is often difficult, especially in curettage material. This distinction is clinically very important to avoid unnecessary hysterectomy. However, only a few immunohistochemical studies of APA that differentiate it from malignancy have been published. Therefore, we have investigated the expression of several antigens in APA and compared them with those present in myoinvasive carcinoma. Six specimens of APA were studied, along with controls of endometrioid carcinoma invading myometrium. Antibodies to p53, Ki-67, CD10, and h-caldesmon reacted positively using immunohistochemistry. Variable positive expressions of p53 and Ki-67 were observed in both epithelial and stromal components of APA, and in myoinvasive endometrioid carcinoma. CD10 was negative or partially and weakly positive whereas h-caldesmon was completely negative in the stromal cells of all 6 specimens of APA. However, in the myometrium in which endometrioid carcinoma invaded, a fringe-like positive staining pattern was occasionally observed for CD10, whereas a diffuse positive signal was obtained for h-caldesmon. The results of this study indicate that immunohistochemically, p53, and Ki-67 are not reliable markers but that h-caldesmon is useful in distinguishing APA from myoinvasive endometrioid carcinoma. Further, our data suggest that the stromal cells of APA are mainly immature smooth muscle cells, and thus APA may be a mixed tumor.

  20. Subglottic Chondrosarcoma Presenting Only Mild Acute-Onset Dyspnea: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Su-wei Tsai

    2014-01-01

    Full Text Available Chondrosarcoma is categorized as a malignant cartilaginous tumor, which occurs rarely in the craniofacial region. We report the case of a 68-year-old man with chondrosarcoma in the subglottic area. His chief symptoms were hoarseness and mild dysphagia. A computed tomography scan revealed a lesion with expansion of the cricoid cartilage and marked reduction of the airway. After biopsy, histological inspection showed that chondrocytes are multi-nucleus, their size does not differ much and mitosis is not obvious. These are all characteristics of a low-grade chondrosarcoma. We performed an organ-preserving operation by debulking the low-grade malignant tumor in order to keep a patent airway. No further metastasis or airway compromise was evident during the 1-year follow-up visit.

  1. Routine aspiration of subglottic secretions after major heart surgery: impact on the incidence of ventilator-associated pneumonia.

    Science.gov (United States)

    Pérez Granda, M J; Barrio, J M; Hortal, J; Muñoz, P; Rincón, C; Bouza, E

    2013-12-01

    Aspiration of subglottic secretions (ASS) is recommended in patients requiring mechanical ventilation for ≥48h. We assessed the impact of the introduction of ASS routinely in all patients after major heart surgery in an ecological study comparing ventilator-acquired pneumonia (VAP) incidence, days of mechanical ventilation, and cost of antimicrobial agents before and after the implementation of ASS. Before and after the intervention the results (per 1000 days) were: VAP incidence, 23.92 vs 16.46 (P = 0.04); cost of antimicrobials, €71,384 vs €63,446 (P = 0.002); and days of mechanical ventilation, 507.5 vs 377.5 (P = 0.009). From the moment of induction of anaesthesia all patients undergoing major heart surgery should routinely receive ASS. Copyright © 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  2. Color Fundus Photography, Optical Coherence Tomography, and Fluorescein Angiography in Diagnosing Polypoidal Choroidal Vasculopathy.

    Science.gov (United States)

    Chaikitmongkol, Voraporn; Khunsongkiet, Preeyanuch; Patikulsila, Direk; Ratanasukon, Mansing; Watanachai, Nawat; Jumroendararasame, Chaisiri; Mayerle, Catherine B; Han, Ian C; Chen, Connie J; Winaikosol, Pawara; Dejkriengkraikul, Chutikarn; Choovuthayakorn, Janejit; Kunavisarut, Paradee; Bressler, Neil M

    2018-05-10

    To determine sensitivity and specificity of polypoidal choroidal vasculopathy (PCV) diagnosis using color fundus photography (CFP), optical coherence tomography (OCT) and fundus fluorescein angiography (FFA) without indocyanine-green angiography (ICGA). Validity analysis. Treatment-naïve eyes with serous/serosanguinous maculopathy undergoing CFP, OCT, FFA and ICGA imaging before treatment at a university-hospital in Thailand (January 2013 to June 2015) were identified. Images of each subject were categorized into 4 sets (set A: CFP; set B: CFP+OCT; set C: CFP+FFA; set D: CFP+OCT+FFA). Six graders, 3 from Thailand (PCV endemic area) and 3 from U.S. (non-endemic area), individually reviewed each set (without ICG), and determined if the presumed diagnosis was PCV. In parallel, 2 other graders confirmed if each case had PCV or not using EVEREST criteria (including ICGA). Sensitivity and specificity of a PCV diagnosis with each set (without ICGA) were analyzed compared with diagnoses including ICGA. Of 119 study eyes (113 subjects, 57% male, mean age±SD 59.9±13.8), definite PCV diagnosis was 40.3%. Sensitivity of sets A, B, C, D: 0.63 (95%CI: 0.47-0.76), 0.83 (95%CI: 0.69-0.92), 0.54 (95%CI: 0.39-0.68), 0.67 (95%CI: 0.51-0.79). Specificity were 0.93 (95% CI: 0.84-0.97), 0.83 (95%CI: 0.72-0.91), 0.97 (95%CI: 0.89-0.99), 0.92 (95%CI: 0.82-0.97). Accuracies: 0.81 (95%CI: 0.73-0.88), 0.83 (95%CI: 0.76-0.90), 0.79 (95%CI: 0.73-0.87), 0.82 (95%CI: 0.74-0.88). Discrepancies between Thai and US graders existed through sets A, C, and D. These data suggest without ICGA, fundus photography combined with OCT provides high sensitivity and high specificity to diagnosis PCV; adding FFA does not improve accuracy. Copyright © 2018 Elsevier Inc. All rights reserved.

  3. Mass

    International Nuclear Information System (INIS)

    Quigg, Chris

    2007-01-01

    In the classical physics we inherited from Isaac Newton, mass does not arise, it simply is. The mass of a classical object is the sum of the masses of its parts. Albert Einstein showed that the mass of a body is a measure of its energy content, inviting us to consider the origins of mass. The protons we accelerate at Fermilab are prime examples of Einsteinian matter: nearly all of their mass arises from stored energy. Missing mass led to the discovery of the noble gases, and a new form of missing mass leads us to the notion of dark matter. Starting with a brief guided tour of the meanings of mass, the colloquium will explore the multiple origins of mass. We will see how far we have come toward understanding mass, and survey the issues that guide our research today.

  4. Vitreous haemorrhage in massive hemorrhagic polypoidal choroidal vasculopathy: clinical characteristics and surgical outcomes: Vitreous hemorrhage in PCV.

    Science.gov (United States)

    Narayanan, Raja; Mithal, Kopal; Jalali, Subhadra; Chhablani, Jay Kumar; Mathai, Annie; Ali, Md Hasnat

    2015-01-01

    To report the outcomes of vitreous hemorrhage (VH) associated with hemorrhagic polypoidal choroidal vasculopathy (PCV). A retrospective study of 28 eyes of 27 consecutive patients of hemorrhagic PCV with VH, which were managed surgically between January 2003 and December 2011, was performed. All patients underwent pars plana vitrectomy for VH associated with PCV. The main outcome measure was best-corrected visual acuity (BCVA) at baseline, at 1, 3 and 6 months post operatively and at last follow up. The visual acuity measured on early treatment diabetic retinopathy study (ETDRS) chart improved in 16 eyes (57.1 %) by two or more lines, remained unchanged in nine eyes (32.1 %) and decreased in three (10.7 %) after surgery when compared to baseline VA. The mean baseline VA was 2.69 ± 0.57 logMAR units (hemorrhagic PCV have sustained improvement in visual acuity following surgery.

  5. Strategies to prevent ventilation-associated pneumonia: the effect of cuff pressure monitoring techniques and tracheal tube type on aspiration of subglottic secretions: an in-vitro study.

    Science.gov (United States)

    Carter, Eleanor L; Duguid, Alasdair; Ercole, Ari; Matta, Basil; Burnstein, Rowan M; Veenith, Tonny

    2014-03-01

    Ventilation-associated pneumonia (VAP) is the commonest nosocomial infection in intensive care. Implementation of a VAP prevention care bundle is a proven method to reduce its incidence. The UK care bundle recommends maintenance of the tracheal tube cuff pressure at 20 to 30  cmH₂O with 4-hourly pressure checks and use of tracheal tubes with subglottic aspiration ports in patients admitted for more than 72  h. To evaluate the effects of tracheal tube type and cuff pressure monitoring technique on leakage of subglottic secretions past the tracheal tube cuff. Bench-top study. Laboratory. A model adult trachea with simulated subglottic secretions was intubated with a tracheal tube with the cuff inflated to 25  cmH₂O. Experiments were conducted using a Portex Profile Soft Seal tracheal tube with three cuff pressure monitoring strategies and using a Portex SACETT tracheal tube with intermittent cuff pressure checks. Rate of simulated secretion leakage past the tracheal tube cuff. Mean ± SD leakage of fluid past the Profile Soft Seal tracheal tube cuff was 2.25 ± 1.49  ml  min⁻¹ with no monitoring of cuff pressure, 2.98 ± 1.63  ml  min⁻¹ with intermittent cuff pressure monitoring and 3.83 ± 2.17  ml  min⁻¹ with continuous cuff pressure monitoring (P aspiration port and aspirating the simulated secretions prior to intermittent cuff pressure checks reduced the leakage rate to 0.50 ± 0.48  ml  min⁻¹ (P aspiration port. Further evaluation of medical device performance is needed in order to design more effective VAP prevention strategies.

  6. T-cell differentiation and CD56+ levels in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration.

    Science.gov (United States)

    Subhi, Yousif; Nielsen, Marie Krogh; Molbech, Christopher Rue; Oishi, Akio; Singh, Amardeep; Nissen, Mogens Holst; Sørensen, Torben Lykke

    2017-11-20

    Polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (AMD) are prevalent age-related diseases characterized by exudative changes in the macula. Although they share anatomical and clinical similarities, they are also distinctly characterized by their own features, e.g. vascular abnormalities in PCV and drusen-mediated progression in neovascular AMD. PCV remains etiologically uncharacterized, and ongoing discussion is whether PCV and neovascular AMD share the same etiology or constitute two substantially different diseases. In this study, we investigated T-cell differentiation and aging profile in human patients with PCV, patients with neovascular AMD, and age-matched healthy control individuals. Fresh venous blood was prepared for flow cytometry to investigate CD4 + and CD8 + T-cell differentiation (naïve, central memory, effector memory, effector memory CD45ra + ), loss of differentiation markers CD27 and CD28, and expression of aging marker CD56. Patients with PCV were similar to the healthy controls in all aspects. In patients with neovascular AMD we found significantly accelerated T-cell differentiation (more CD28 - CD27 - cells) and aging (more CD56 + cells) in the CD8 + T-cell compartment. These findings suggest that PCV and neovascular AMD are etiologically different in terms of T cell immunity, and that neovascular AMD is associated with T-cell immunosenescence.

  7. Management of embedded metallic stents used in the treatment of grades III and IV subglottic, and upper tracheal stenosis in adults.

    Science.gov (United States)

    Sendi, Khalil; Al-Khatib, Talal; Ahmed, Duha G; Tonkul, Al-Baraa

    2014-11-01

    The aim of this study was to evaluate the post-operative complications of using balloon-expandable metallic stents in treatment of benign, major subglottic and tracheal stenosis in adult patients whom conventional therapy has failed and to demonstrate how to deal with these complications in the long run. A retrospective review of five cases; adlut patiets with benign, major subglottic and upper tracheal stenosis whom were treated with balloon expandable metallic stents at King Abdulaziz University Hospital, in the years between 2008 and 2013. Granulation tissue formed in five of the four cases and restenosis occurred. Other complications encountered were stent infection and dislodgment. The complications were managed by removing the stents surgically via a laryngofissure incision and required the placement of a Montgomery T-tube. Managing the restenosis due to granulation tissue formation around the metallic stents is best achieved by removing the embedded metallic stents surgically via open technique and then by placement of a Montgomery T-tube as a bridging option to successful decannulation. Open surgical procedures remain the mainstay treatment for advanced airway stenosis.

  8. Efficacy of continuous versus intermittent subglottic secretion drainage in preventing ventilator-associated pneumonia in patients requiring mechanical ventilation: A single-center randomized controlled trial.

    Science.gov (United States)

    Fujimoto, Hiroko; Yamaguchi, Osamu; Hayami, Hajime; Shimosaka, Mika; Tsuboi, Sayaka; Sato, Mitsunori; Takebayashi, Shigeo; Morita, Satoshi; Saito, Mari; Goto, Takahisa; Kurahashi, Kiyoyasu

    2018-03-23

    Aspiration of subglottic secretion is a widely used intervention to prevent ventilator-associated pneumonia (VAP). This study aimed to compare the efficacy of continuous and intermittent subglottic secretion drainage (SSD) in preventing VAP. A single-center randomized controlled trial was conducted on adult postoperative patients who were expected to undergo mechanical ventilation for more than 48 hours. Primary outcome measure was incidence of VAP and secondary outcome measures were length of mechanical ventilation and intensive-care unit (ICU) stay. Fifty-nine patients received continuous SSD, while 60 patients received intermittent SSD. Of these 119 patients, 88 (74%) were excluded and 15 and 16 patients were allocated to receive continuous and intermittent SSD, respectively. VAP was detected in 4 (26.7%) and 7 (43.8%) patients in the continuous and intermittent groups, respectively, (p=0.320). The length of mechanical ventilation was significantly shorter (p=0.034) in the continuous group (99.5±47.1 h) than in the intermittent group (159.9±94.5 h). The length of ICU stay was also shorter (p=0.0097) in the continuous group (6.3±2.1 days) than the intermittent group (9.8±4.8 days). Although continuous SSD did not reduce the incidence of VAP, it reduced the length of mechanical ventilation and ICU stay when compared to intermittent SSD.

  9. [Effect of continuous aspiration of subglottic secretions on the prevention of ventilator-associated pneumonia in mechanically ventilated patients: a prospective, randomized, controlled clinical trial].

    Science.gov (United States)

    Yang, Cong-shan; Qiu, Hai-bo; Zhu, Yan-ping; Huang, Ying-zi; Xu, Xiao-ting; Gao, Liang

    2008-08-01

    To evaluate the effect of continuous aspiration of subglottic secretions (CASS) on the prevention of ventilator-associated pneumonia (VAP) in mechanically ventilated patients. Patients ventilated mechanically at the ICU from October, 2004 to April, 2006 were randomly divided into 2 groups: one group received CASS and the other did not (NASS group). CASS was performed immediately after admission for patients in the CASS group. The diagnosis of VAP was made based on clinical presentations, and the evaluation of VAP was done using simplified version of the clinical pulmonary infection score (CPIS). The general status of the patients, days of ventilated treatment, the volume of daily aspirated subglottic secretions, the morbidity and timing of VAP, days of stay in ICU and mortality within 28 days of hospitalization were recorded. One hundred and one patients were included in the study. There were 48 patients in the CASS group who were treated with mechanical ventilation more than 48 hours, and 43 patients in the NASS group. There was no significant difference in the general status of the patients and days of ventilation between 2 groups with the averaged score of APACHE II being 20.8 +/- 6.1. The average of CPIS was of 5.6 +/- 1.0 when VAP was diagnosed. The mean volume of aspirated subglottic secretions within the first 24 hours in the CASS group (n = 48) was (27.2 +/- 21.2) ml. The morbidity of VAP in the CASS and the NASS groups was 25.0% and 46.5% respectively (P = 0.032), and the length of time before the onset of VAP in these 2 groups was (7.3 +/- 4.2) days and (5.1 +/- 3.0) days respectively (P = 0.100). There was a significant increase in the percentage of gram-positive cocci from the lower respiratory tracts in the NASS group compared with that in the CASS group (P = 0.004). In the CASS group, the volume of the first daily aspirated subglottic secretions in patients with VAP was significantly less than that in patients without VAP (P = 0.006). The morbidity of

  10. [A case of polypoid bronchial neurofibroma originating from right B2b successfully treated by bronchoscopic snaring forceps and Nd-YAG laser therapy].

    Science.gov (United States)

    Takiguchi, Y; Uchiyama, T; Sato, K; Tatsumi, K; Kimura, H; Nagao, K; Fujisawa, T; Ohwada, H; Hiroshima, K; Kuriyama, T

    1993-12-01

    A 34-year-old man with persistent cough was admitted to our hospital. Bronchoscopic examination revealed a polypoid tumor with smooth surface which almost completely obstructed the right main bronchus. The tumor was removed by transbronchial snaring forceps and histologically confirmed as neurofibroma. Residual tumor was excised by biopsy forceps and further endoscopic Nd-YAG laser vaporization was performed. This is the first case in our country in which bronchoscopic treatment was performed for bronchial neurofibroma. Bronchoscopic removal might be the preferred treatment in the present case, although long-term follow-up is also required.

  11. Major single nucleotide polymorphisms in polypoidal choroidal vasculopathy: a comparative analysis between Thai and other Asian populations

    Directory of Open Access Journals (Sweden)

    Chantaren P

    2012-03-01

    Full Text Available Patchima Chantaren1, Paisan Ruamviboonsuk1, Mathurose Ponglikitmongkol2, Montip Tiensuwan3, Somying Promso41Department of Ophthalmology, Rajavithi Hospital, Bangkok, 2Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, 3Department of Mathematics, Faculty of Science, Mahidol University, Bangkok, 4Virology and Molecular Microbiology Unit, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandPurpose: To investigate the association in a Thai population between the major age-related macular degeneration (AMD susceptibility loci, Y402H and I62V in the complement factor H (CFH and A69S in the age-related maculopathy susceptibility 2 (ARMS2 genes, and polypoidal choroidal vasculopathy (PCV.Methods: A case-control study included 97 PCV cases and 102 age- and gender-matched controls without any retinopathy. The genotypic profiles of the three polymorphisms were obtained using a real-time polymerase chain reaction assay. The allelic and genotypic association between the polymorphisms and PCV were compared with those from the compiled data of other Asian populations reported previously.Results: Strong associations between the Y402H, I62V, and A69S polymorphisms and PCV were observed in the present study (P = 0.002, 0.003, and 0.0008 respectively and in the compiled data (P < 0.0001 for all three polymorphisms. The risk allele frequencies of the polymorphisms in PCVs and in controls from the present study (15.0% and 5.4% for Y402H, 71.7% and 57.4% for I62V, and 54.1% and 37.3% for A69S respectively were also comparable with the frequencies from the compiled data (10.3% and 6.4% for Y402H, 75.2% and 58.3% for I62V, and 56.8% and 36.8% for A69S respectively. The genotype distribution for each polymorphism was also comparable in both datasets.Conclusion: The findings of this study support a significant genetic association between the major AMD susceptibility genes and PCV across Asian

  12. Continuous aspiration of subglottic secretions in the prevention of ventilator-associated pneumonia in the postoperative period of major heart surgery.

    Science.gov (United States)

    Bouza, Emilio; Pérez, María Jesús; Muñoz, Patricia; Rincón, Cristina; Barrio, José María; Hortal, Javier

    2008-11-01

    Aspiration of endotracheal secretions is a major step in the prevention of ventilator-associated pneumonia (VAP). We compared conventional and continuous aspiration of subglottic secretions (CASS) procedures in ventilated patients after major heart surgery (MHS). Randomized comparison during a 2-year period. A total of 714 patients were randomized (24 patients were excluded from the study; 359 CASS patients; 331 control subjects). The results for CASS patients and control subjects (per protocol and intention-to-treat analysis) were as follows: VAP incidence, 3.6% vs 5.3% (p = 0.2) and 3.8% vs 5.1%, respectively; incidence density, 17.9 vs 27.6 episodes per 1,000 days of mechanical ventilation (MV) [p = 0.18] and 18.9 vs 28.7 episodes per 1,000 days of MV, respectively; hospital antibiotic use in daily defined doses (DDDs), 1,213 vs 1,932 (p 48 h, the comparisons of CASS patients and control subjects were as follows: VAP incidence, 26.7% vs 47.5% (p = 0.04), respectively; incidence density, 31.5 vs 51.6 episodes per 1,000 days of MV, respectively (p = 0.03); median length of ICU stay, 7 vs 16.5 days (p = 0.01), respectively; hospital antibiotic use, 1,206 vs 1,877 DDD (p VAP (relative risk [RR], 6.07; 95% confidence interval [CI], 2.20 to 16.60; p VAP in patients who are at risk. CASS use should be encouraged, at least in patients undergoing MHS.

  13. On the single-mass model of the vocal folds

    International Nuclear Information System (INIS)

    Howe, M S; McGowan, R S

    2010-01-01

    An analysis is made of the fluid-structure interactions necessary to support self-sustained oscillations of a single-mass mechanical model of the vocal folds subject to a nominally steady subglottal overpressure. The single-mass model of Fant and Flanagan is re-examined and an analytical representation of vortex shedding during 'voiced speech' is proposed that promotes cooperative, periodic excitation of the folds by the glottal flow. Positive feedback that sustains glottal oscillations is shown to occur during glottal contraction, when the flow separates from the 'trailing edge' of the glottis producing a low-pressure 'suction' force that tends to pull the folds together. Details are worked out for flow that can be regarded as locally two-dimensional in the glottal region. Predictions of free-streamline theory are used to model the effects of quasi-static variations in the separation point on the glottal wall. Numerical predictions are presented to illustrate the waveform of the sound radiated towards the mouth from the glottis. The theory is easily modified to include feedback on the glottal flow of standing acoustic waves, both in the vocal tract beyond the glottis and in the subglottal region. (invited paper)

  14. The association of age-related maculopathy susceptibility 2 (ARMS2) and complement factor H (CFH) variants with two angiographic subtypes of polypoidal choroidal vasculopathy.

    Science.gov (United States)

    Miki, Akiko; Honda, Shigeru; Kondo, Naoshi; Negi, Akira

    2013-09-01

    To compare the association of age-related maculopathy susceptibility 2 (ARMS2) and complement factor H (CFH) variants between two different angiographic phenotypes of polypoidal choroidal vasculopathy (PCV). We included 175 Japanese patients with PCV and 150 age- and sex-matched controls. PCV was classified into two phenotypes (Type 1 and Type 2) according to the presence or absence of the feeding vessels found in indocyanine-green angiography. The single nucleotide polymorphism (SNP) at rs10490924 (A69S) in ARMS2 and rs800292 (I62V), rs1061170 (Y402H) in the CFH region were genotyped using the TaqMan assay. The minor allele frequency (MAF) of rs10490924 was significantly different between Type 1 PCV (n = 81) and control (p < 0.0001), while no difference was found between Type 2 PCV (n = 94) and control (p = 0.20). The MAF of rs800292 was significantly different between each type of PCV and control (p < 0.0001 and 0.0001 for Type 1 versus control and Type 2 versus control, respectively). The MAF of rs1061170 was not significantly different between either type of PCV and control (p = 0.084 and 0.15, respectively). There may be significantly different associations in the genetic variants of ARMS2 between two angiographic phenotypes of PCV.

  15. Development and clinical use of a software for the analysis of the diagnosis and the features of polypoid lesions of the colon and rectum

    International Nuclear Information System (INIS)

    Bellomi, M.; Pestalozza, M.A.; Bellegotti, L.; Gardani, G.S.; Graziano, M.

    1987-01-01

    Double contrast enema and endoscopy are very important in the diagnosis of adenomas and early cancer of the colon and rectum. These exams can not only detect the presence, but also suggest the histologic diagnosis, of polypoid lesions of the colon. An Olivetti M24 Personal Computer was used to create a software to study the results obtained by double contrast enema, and to compare them with endoscopy and pathology. The data base is formed by 7 files: one anagraphic, 3 collecting the characteristics of the diagnosis - namely the radiologic, the endoscopic and the pathologic one - and 3 multiple files featuring each lesion, as defined by the three diagnostic techniques. The software allows to evaluate the different lesions that can be detected by three techniques in the same patient and to compare the diagnosis of presence to the morphologic features of each lesion. False negatives and false positive of each technique are easily recognized. It is also possible to characterize the single morphological feature leading the radiologist and/or the endoscopist to express an opinion about the histologic diagnosis of each lesion and to compare them with pathological features. The first experience in clinical use of the software, in the analysis of the characters of 336 lesions in 218 patients, is described

  16. Preoperative care of Polypoid exposed mucosal template in bladder exstrophy: the role of high-barrier plastic wraps in reducing inflammation and polyp size.

    Science.gov (United States)

    Sabetkish, Nastaran; Sabetkish, Shabnam; Kajbafzadeh, Abdol-Mohammad

    2018-01-26

    To assess the role of high-barrier plastic wrap in reducing the number and size of polyps, as well as decreasing the inflammation and allergic reactions in exstrophy cases, and to compare the results with the application of low-barrier wrap. Eight patients with bladder exstrophy-epispadias complex (BEEC) that had used a low density polyethylene (LDPE) wrap for coverage of the exposed polypoid bladder in preoperative care management were referred. The main complaint of their parents was increase in size and number of polyps. After a period of 2 months using the same wrap and observing the increasing pattern in size of polyps, these patients were recommended to use a high-barrier wrap which is made of polyvinylidene chloride (PVdC), until closure. Patients were monitored for the number and size of polyps before and after the change of barriers. The incidence of para-exstrophy skin infection/inflammation and skin allergy were assessed. Biopsies were taken from the polyps to identify histopathological characteristics of the exposed polyps. The high barrier wrap was applied for a mean ± SD duration of 12±2.1 months. Polyps' size and number decreased after 12 months. No allergic reaction was detected in patients after the usage of PVdC; three patients suffered from low-grade skin allergy when LDPE was applied. Also, pre-malignant changes were observed in none of the patients in histopathological examination after the application of PVdC. Polyps' size and number and skin allergy may significantly decrease with the use of a high-barrier wrap. Certain PVdC wraps with more integrity and less evaporative permeability may be more "exstrophy-friendly". Copyright® by the International Brazilian Journal of Urology.

  17. Ranibizumab alone or in combination with photodynamic therapy vs photodynamic therapy for polypoidal choroidal vasculopathy: a systematic review and Meta-analysis.

    Science.gov (United States)

    Tang, Kai; Si, Jun-Kang; Guo, Da-Dong; Cui, Yan; Du, Yu-Xiang; Pan, Xue-Mei; Bi, Hong-Sheng

    2015-01-01

    To compare the efficacy of intravitreal ranibizumab (IVR) alone or in combination with photodynamic therapy (PDT) vs PDT in patients with symptomatic polypoidal choroidal vasculopathy (PCV). A systematic search of a wide range of databases (including PubMed, EMBASE, Cochrane Library and Web of Science) was searched to identify relevant studies. Both randomized controlled trials (RCTs) and non-RCT studies were included. Methodological quality of included literatures was evaluated according to the Newcastle-Ottawa Scale. RevMan 5.2.7 software was used to do the Meta-analysis. Three RCTs and 6 retrospective studies were included. The results showed that PDT monotherapy had a significantly higher proportion in patients who achieved complete regression of polyps than IVR monotherapy at months 3, 6, and 12 (All P≤0.01), respectively. However, IVR had a tendency to be more effective in improving vision on the basis of RCTs. The proportion of patients who gained complete regression of polyps revealed that there was no significant difference between the combination treatment and PDT monotherapy. The mean change of best-corrected visual acuity (BCVA) from baseline showed that the combination treatment had significant superiority in improving vision vs PDT monotherapy at months 3, 6 and 24 (All Pcompare with PDT either in stabilizing or in improving vision, although it can hardly promote the regression of polyps. The combination treatment of PDT and IVR can exert a synergistic effect on regressing polyps and on maintaining or improving visual acuity. Thus, it can be the first-line therapy for PCV.

  18. Glottic cancer with subglottic extension

    International Nuclear Information System (INIS)

    Ampil, F.L.; Menezes, C.-A.O.

    1997-01-01

    The outcomes of 27 patients with glottic cancer extending into the subglottis (GCSE) who were treated by surgery and radiation (n=17) or radiation alone (n=10) during a 13-year period were retrospectively reviewed. Since this study was nonrandomized and retrospective, the patient groups were not equally matched with regard to age (p>0.05), gender (p>0.30), or disease stage (p>0.05). The locoregional failure rate was 18±(95% CI) 20% in patients who received combined therapy and 40±31% in persons treated by radiation alone (p=0.20); the corresponding survival rates at two years were 53±24% and 42±31% (p>0.50). These findings suggest that GCSE may be better managed by a combination of surgery and radiotherapy than by the use of radiotherapy alone. (author)

  19. Anaesthesia and subglottic airway obstruction

    African Journals Online (AJOL)

    2009-07-14

    Jul 14, 2009 ... Introduction. Surgery on the upper airway remains challenging for both surgeon and ... from her upper airway obstruction rather than asthma.1 She had made a long ... patient was well oxygenated with oxygen saturation above. 95%. .... Difficulties relate to tidal volume measurement, CO2 detection and the.

  20. SPECTRUM OF SINONASAL MASS AT A TERTIARY LEVEL HOSPITAL

    Directory of Open Access Journals (Sweden)

    Amit Kumar Bhardwaj

    2016-11-01

    Full Text Available BACKGROUND Lesions of the sinonasal region are commonly encountered in clinical practice. These lesions are important from clinical and pathological view as they have a variety of histological spectrum with different managements. MATERIALS AND METHODS Present study included 106 polypoidal lesions of the nasal cavity. The study period constituted from March 2003 to August 2014. All the tissues were fixed in 10% buffered formalin, processed and stained with Haematoxylin and Eosin and studied for various histopathological patterns. RESULTS Among 106 cases, 87 cases (82.07% were nonneoplastic and 19 cases (17.92% were neoplastic. Among the noninflammatory lesion, nasal polyp was found in 76 cases (87.7% and was the commonest lesion. Benign tumours were 11 in number (10.35% and were more frequent than malignant tumours, which were 8 in number (7.54%. Among benign neoplastic lesions, angiofibroma and haemangioma (each 4 in number (36.36% were the commonest lesion. All lesions were common in second and third decades with male predominance in benign, while malignant lesions were more common in female gender. Among the malignant lesions, squamous cell carcinoma and undifferentiated nasopharyngeal carcinoma were the most common malignant lesions, each were three in number. CONCLUSION Categorisation of the sinonasal mass according to their histopathological features and comparing them with the existing data guides the treatment and prognosis of the disease, so far every polypoidal lesions histological examination is advised.

  1. A prospective study of treatment patterns and 1-year outcome of Asian age-related macular degeneration and polypoidal choroidal vasculopathy.

    Directory of Open Access Journals (Sweden)

    Chui Ming Gemmy Cheung

    Full Text Available OBJECTIVE: To study the treatment patterns and visual outcome over one year in Asian patients with choroidal neovascular membrane secondary to age-related macular degeneration (AMD-CNV and polypoidal choroidal vasculopathy (PCV. DESIGN: Prospective cohort, non-interventional study. METHODS: 132 treatment-naïve patients who received treatment for AMD-CNV and PCV were included. All patients underwent standardized examination procedures including retinal imaging at baseline and follow-up. AMD-CNV and PCV were defined on fundus fluorescein angiography and indocyanine green angiography at baseline. Patients were treated according to standard of care.We report the visual acuity (VA and optical coherence tomography (OCT measurements at baseline, month 3 and month 12 The factors influencing month 12 outcomes were analyzed. MAIN OUTCOME MEASURE: Type of treatment, number of Anti-vascular endothelial growth factor (VEGF treatments, visual outcome over one year. RESULTS: Anti-VEGF monotherapy was the initial treatment in 89.1% of AMD-CNV, but only 15.1% of PCV. The mean number of anti-VEGF injections up to month 12 was 3.97 (4.51 AMD-CNV, 3.43 PCV, p = 0.021. Baseline OCT, month 3 OCT and month 3 VA were significant in determining continuation of treatment after month 3. At month 12, mean VA improved from 0.82 (∼20/132 at baseline to 0.68 (∼20/96 at month 12 (mean gain 6.5 ETDRS letters, p = 0.002. 34.2% of eyes (38/113 eyes gained ≥15 ETDRS letters and 14.4% (16/113 eyes lost ≥15 ETDRS letters. There were no significant differences in visual outcome between AMD-CNV and PCV (p = 0.51. Factors predictive of month 12 visual outcome were baseline VA, baseline OCT central macular thickness, month 3 VA and age. CONCLUSIONS: There is significant variation in treatment patterns in Asian eyes with exudative maculopathy. There is significant visual improvement in all treatment groups at one year. These data highlight the need for high quality

  2. Prognostic value of age, subglottic, and anterior commissure involvement for early glottic carcinoma treated with CO2 laser transoral microsurgery: a retrospective, single-center cohort study of 261 patients.

    Science.gov (United States)

    Carta, Filippo; Bandino, Fabrizio; Olla, Aurora Marta; Chuchueva, Natalia; Gerosa, Clara; Puxeddu, Roberto

    2018-05-01

     CO 2 laser transoral microsurgery for glottic carcinoma, when indicated, has the well-established advantages of low morbidity and positive oncological outcomes. The present study aims to determine how patient age, and tumor site could negatively impact prognosis; other variables such as the status of the margins of resection, tobacco and alcohol intake, and the grade of differentiation of the tumors have been evaluated. This was a retrospective analysis on 261 patients with a glottic carcinoma who underwent CO 2 laser transoral microsurgery. The impact of different variables was calculated using univariate and multivariate analyses. The study included 248 males and 13 females. The median follow-up period was 4.3 years. Five-year disease-specific survival, recurrence-free survival, local control with laser alone, overall laryngeal preservation, and overall survival rates were 99.4, 92.2, 93.8, 97.6, and 85.5%, respectively. Equivalent results were observed in young and elderly patients. Patients with positive margins after CO 2 laser transoral microsurgery showed a reduced local control with laser alone. T2 patients with true subglottic spreading and patients with anterior commissure involvement of grade 3 (Rucci's classification) experienced worse local control rates, despite free surgical margins confirmed by histology.  CO 2 laser transoral microsurgery is an effective and reproducible single-stage modality therapy for young and elderly patients with glottic carcinoma. Superficial close margins can be managed by a careful wait-and-see policy, while positive margins should undergo surgical enlargement. In our experience, undifferentiated tumors, true subglottic extension, and anterior commissure involvement of grade 3 were associated with worse outcomes.

  3. Prospective evaluation of subretinal vessel location in polypoidal choroidal vasculopathy (PCV) and response of hemorrhagic and exudative PCV to high-dose antiangiogenic therapy (an American Ophthalmological Society thesis).

    Science.gov (United States)

    Kokame, Gregg T

    2014-07-01

    The purpose of this study was to determine the following: (1) Is polypoidal choroidal vasculopathy (PCV) a subretinal neovascular process, rather than a choroidal vascular anomaly? and (2) Is a higher dose of ranibizumab (2.0 mg/0.05 mL) more effective in treating PCV than the current dose (0.5 mg/0.05 mL) approved for treatment of age-related macular degeneration? Retrospective evaluation of PCV in 104 eyes of 86 patients was accomplished with use of indocyanine green angiography plus optical coherence tomography to localize the branching vascular network and the polyps. Nineteen eyes of 19 patients with active leaking and exudation underwent a prospective open-label trial of monthly high-dose intravitreal ranibizumab (2.0 mg/0.05 mL). The primary outcome was prevention of major vision loss (≤15 ETDRS letters). Secondary outcomes included adverse events, improved vision, and changes in subretinal hemorrhage, subretinal fluid, macular edema, and polypoidal complexes at 6 months. The PCV vessels were localized beneath the retinal pigment epithelium (RPE) and above Bruch's membrane in 103 (99%) of 104 eyes. In the high-dose ranibizumab trial at 6 months, none of the patients lost ≥15 letters in visual acuity, and 5 (26%) of 19 gained ≥15 letters. Decreases were noted in subretinal fluid in 14 (82%) of 17 eyes, subretinal hemorrhage in 12 (100%) of 12, RPE detachment in 14 (88%) of 16, macular edema in 11 (92%) of 12, and polyps in 15 (79%) of 19 eyes. PCV vessels are a subtype of subretinal neovascularization located above Bruch's membrane and below RPE. High-dose ranibizumab (2.0 mg/0.05 mL) decreased exudation and hemorrhage and resulted in significant polyp regression, although branching vascular networks persisted.

  4. Difference between age-related macular degeneration and polypoidal choroidal vasculopathy in the hereditary contribution of the A69S variant of the age-related maculopathy susceptibility 2 gene (ARMS2).

    Science.gov (United States)

    Yanagisawa, Suiho; Kondo, Naoshi; Miki, Akiko; Matsumiya, Wataru; Kusuhara, Sentaro; Tsukahara, Yasutomo; Honda, Shigeru; Negi, Akira

    2011-01-01

    To investigate whether the A69S variant of the age-related maculopathy susceptibility 2 gene (ARMS2) has a different hereditary contribution in neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). We initially conducted a comparative genetic analysis of neovascular AMD and PCV, genotyping the ARMS2 A69S variant in 181 subjects with neovascular AMD, 198 subjects with PCV, and 203 controls in a Japanese population. Genotyping was conducted using TaqMan technology. Results were then integrated into a meta-analysis of previous studies representing an assessment of the association between the ARMS2 A69S variant and neovascular AMD and/or PCV, comprising a total of 3,828 subjects of Asian descent. The Q-statistic test was used to assess between-study heterogeneity. Summary odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using a fixed effects model. The genetic effect of the A69S variant was stronger in neovascular AMD (allelic summary OR=3.09 [95% CI, 2.71-3.51], fixed effects parchitecture of this phenotypically heterogeneous disorder.

  5. Estenose subglótica como manifestação clínica da granulomatose de Wegener em adolescentes: relato de caso e revisão de literatura Subglottic stenosis as a clinical manifestation of Wegener's granulomatosis in adolescents: report of a case and review of literature

    Directory of Open Access Journals (Sweden)

    Márcia C. Machado

    2003-10-01

    Full Text Available A Granulomatose de Wegener é uma patologia caracterizada por vasculite sistêmica e inflamação granulomatosa necrotizante que compromete o trato respiratório alto, pulmões e rins, cujas manifestações iniciais, na maioria das vezes, ocorre em maiores de 20 anos de idade. As queixas clínicas otorrinolaringológicas estão, com freqüência, presentes nas fases iniciais da doença, sendo rinite, sinusopatia de repetição e epistaxe as mais comuns. A estenose subglógica parece estar correlacionada com a Granulomatose de Wegener em adolescentes. Relatamos o caso de uma paciente portadora de Granulomatose de Wegener cujo início dos sintomas foi na infância, tendo evoluído com estenose laríngea durante o curso da doença.Wegener's Granulomatosis is a well-characterized systemic vasculitis and necrotising granulomatous inflammation of the upper, lower respiratory tracts and the kidneys. The initial manifestations of the disease usually occur in patients over than twenty years old. The otolaryngologic symptoms like rhinorrhea, recurrent sinusitis and epistaxis are commonly present in early course of the disease. It seems that subglottic stenosis is correlated to Wegener's granumatosis in adolescents. We describe a case of a patient that developed subglottic stenosis associated with Wegener's granulomatosis in childhood during the course of the disease.

  6. Mass discrimination

    Energy Technology Data Exchange (ETDEWEB)

    Broeckman, A. [Rijksuniversiteit Utrecht (Netherlands)

    1978-12-15

    In thermal ionization mass spectrometry the phenomenon of mass discrimination has led to the use of a correction factor for isotope ratio-measurements. The correction factor is defined as the measured ratio divided by the true or accepted value of this ratio. In fact this factor corrects for systematic errors of the whole procedure; however mass discrimination is often associated just with the mass spectrometer.

  7. Negative mass

    International Nuclear Information System (INIS)

    Hammond, Richard T

    2015-01-01

    Some physical aspects of negative mass are examined. Several unusual properties, such as the ability of negative mass to penetrate any armor, are analysed. Other surprising effects include the bizarre system of negative mass chasing positive mass, naked singularities and the violation of cosmic censorship, wormholes, and quantum mechanical results as well. In addition, a brief look into the implications for strings is given. (paper)

  8. Nominal Mass?

    Science.gov (United States)

    Attygalle, Athula B; Pavlov, Julius

    2017-08-01

    The current IUPAC-recommended definition of the term "nominal mass," based on the most abundant naturally occurring stable isotope of an element, is flawed. We propose that Nominal mass should be defined as the sum of integer masses of protons and neutrons in any chemical species. In this way, all isotopes and isotopologues can be assigned a definitive identifier. Graphical Abstract ᅟ.

  9. NEUTRINO MASS

    OpenAIRE

    Kayser, Boris

    1988-01-01

    This is a review article about the most recent developments on the field of neutrino mass. The first part of the review introduces the idea of neutrino masses and mixing angles, summarizes the most recent experimental data then discusses the experimental prospects and challenges in this area. The second part of the review discusses the implications of these results for particle physics and cosmology, including the origin of neutrino mass, the see-saw mechanism and sequential dominance, and la...

  10. Neutrino mass

    International Nuclear Information System (INIS)

    Robertson, R.G.H.

    1992-01-01

    Despite intensive experimental work since the neutrino's existence was proposed by Pauli 60 years ago, and its first observation by Reines and Cowan almost 40 years ago, the neutrino's fundamental properties remain elusive. Among those properties are the masses of the three known flavors, properties under charge conjugation, parity and time-reversal, and static and dynamic electromagnetic moments. Mass is perhaps the most fundamental, as it constrains the other properties. The present status of the search for neutrino mass is briefly reviewed

  11. Vasculopatia polipoidal idiopática da coróide: aspectos extremos da evolução da doença em um paciente - Relato de caso Idiopathic polypoidal choroidal vasculopathy: its extreme aspects in one patient - Case report

    Directory of Open Access Journals (Sweden)

    Ieda Maria Alexandre Barreira

    2005-04-01

    Full Text Available O artigo descreve um caso de vasculopatia polipoidal idiopática da coróide (VPIC e demonstra o papel relevante da indocianinografia no diagnóstico diferencial com outras causas de neovascularização subretiniana, particularmente degeneração macular relacionada à idade (DMRI, bem como avalia os aspectos extremos na evolução da doença em um único paciente. Paciente de 54 anos, sexo masculino, cor parda, com queixas de baixa de acuidade visual súbita em OD, foi submetido a exame oftalmológico, pelo qual se constatou hemorragia vítrea em OD e, posteriormente, descolamento sero-hemorrágico do epitélio pigmentário da retina em OE. A angiofluoresceinografia e indocianinografia mostraram quadro compatível com vasculopatia polipoidal idiopática da coróide. O paciente foi submetido a vitrectomia via pars plana em OD e foi acompanhado por período de 5 meses, evoluindo com perda de visão secundária a descolamento de retina e cicatriz macular disciforme em OD. No olho contralateral, ocorreu involução da vasculopatia com preservação de acuidade visual 20/25. A vasculopatia polipoidal idiopática da coróide é entidade clínica cujas anormalidades do fundo de olho se sobrepõem às manifestações da degeneração macular relacionada à idade exsudativa. A indocianinografia é de vital importância no diagnóstico diferencial entre as duas doenças que tem evolução e prognóstico distintos. Além disso, consideramos este caso muito ilustrativo pelas diferentes nuances com que a doença se manifestou e evoluiu em um único paciente.To describe a case of idiopathic polypoidal choroidal vasculopathy and the role of indocyanine green angiography findings in the differential diagnosis of exsudative maculopathies, particularly with age-related macular degeneration, and the extreme evolution of idiopathic polypoidal choroidal vasculopathy in one patient. A patient with vitreous hemorrhage was examined and evaluated by fluorescein and

  12. Mass Society

    DEFF Research Database (Denmark)

    Borch, Christian

    2017-01-01

    the negative features usually ascribed by late nineteenth-century crowd psychology to spontaneous crowds, and attributes these to the entire social fabric. However, in contrast to crowd psychology, theorists of mass society often place greater emphasis on how capitalism, technological advances, or demographic......Mass society is a societal diagnosis that emphasizes – usually in a pejorative, modernity critical manner – a series of traits allegedly associated with modern society, such as the leveling of individuality, moral decay, alienation, and isolation. As such, the notion of mass society generalizes...... developments condition such negative features, and some theorists argue that mass society produces a propensity to totalitarianism. Discussions of mass society culminated in the early and mid-twentieth century....

  13. Mass hysteria

    CERN Document Server

    Hellemans, Alexander

    2004-01-01

    Considerable research is being undertaken to identify the Higgs particle that is believed to give things their mass. According to the standard model, what we call mass is really an indication of how strongly particles interact with an invisible syrupy substance called the Higgs field. Quantum mechanics say that the mass-giving field can also be thought of as a sea of electrically neutral Higgs particles that should be dislodged in collisions between subatomic particles with high enough energies. Particle physicists expect the Higgs to exist only for a fleeting moment before decaying into other particles, which are caught in a detector. (Edited abstract).

  14. Neutrino mass?

    International Nuclear Information System (INIS)

    Kayser, B.

    1992-01-01

    After arguing that we should be looking for evidence of neutrino mass, we illustrate the possible consequences of neutrino mass and mixing. We then turn to the question of whether neutrinos are their own antiparticles, and to the process which may answer this question: neutrinoless double beta decay. Next, we review the proposed Mikheyev-Smirnov-Wolfenstein solution to the solar neutrino problem, and discuss models which can generate neutrino electromagnetic moments large enough to play a role in the sun. Finally, we consider how the possible 17 keV neutrino, if real, would fit in with everything we know about neutrinos. (orig.)

  15. Mass metrology

    CERN Document Server

    Gupta, S V

    2012-01-01

    This book presents the practical aspects of mass measurements. Concepts of gravitational, inertial and conventional mass and details of the variation of acceleration of gravity are described. The Metric Convention and International Prototype Kilogram and BIPM standards are described. The effect of change of gravity on the indication of electronic balances is derived with respect of latitude, altitude and earth topography. The classification of weights by OIML is discussed. Maximum permissible errors in different categories of weights prescribed by national and international organizations are p

  16. Mass spectrometry

    DEFF Research Database (Denmark)

    Nyvang Hartmeyer, Gitte; Jensen, Anne Kvistholm; Böcher, Sidsel

    2010-01-01

    Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is currently being introduced for the rapid and accurate identification of bacteria. We describe 2 MALDI-TOF MS identification cases - 1 directly on spinal fluid and 1 on grown bacteria. Rapidly obtained...

  17. Congenital hairy polyp of the oropharynx presenting as an esophageal mass in a neonate, a case report and literature review.

    Science.gov (United States)

    Richter, Amy; Mysore, Krupa; Schady, Deb; Chandy, Binoy

    2016-01-01

    To review the literature of congenital hairy polyps and describe the clinical presentation, operative management, and histologic findings of a congenital hairy polyp arising from the palatopharyngeus muscle in a neonate with recurrent choking episodes. Chart review of a 2-month-old male referred to a tertiary care pediatric hospital. We present a case of a 2-month-old male who presented to the emergency room with recurrent episodes of choking and vomiting. The patient was previously healthy with no prior medical or neonatal history. The parents noted a small fleshy mass in the patient's oropharynx that he would chew on and swallow after several minutes. However, on physical exam, there was no evidence of oropharyngeal mass. The patient did not have respiratory distress. Imaging revealed a 22×7×11mm oblong, fatty mass in the lower cervical and upper thoracic esophagus with a thin stalk extending proximally to the upper collapsed esophagus. Intraoperative recorded laryngoscopy revealed a pedunculated soft palate mass attached to the right superior palatopharyngeus muscle. Histopathology revealed ectodermal and mesodermal elements in a polypoid structure lined by keratinizing squamous epithelium with adnexal structures and central mature adipose tissue, consistent with congenital hairy polyp resembling an accessory tragus of the ear and branchial anomaly. At 6-week follow up, the patient was doing well and gaining weight appropriately with no further choking episodes. There was no evidence of velopharyngeal dysfunction on follow up exam. The surgical site was completely healed and there was no evidence of recurrence. Congenital hairy polyps of the naso- and oropharynx are rare but may present as airway or esophageal masses, causing respiratory distress or choking episodes in a pediatric patient. The pathologic findings of keratinizing squamous epithelium, adnexal structures, adipose and cartilage tissues resemble congenital accessory tragus and may be considered a

  18. Mass Sports

    Directory of Open Access Journals (Sweden)

    Elena Grigoryeva

    2017-03-01

    Fitness has become one of the most popular kinds of the mass sport and has completely replaced the traditional “physical culture”. Dozens of variations of fitness and millions of participants pose a great challenge to contemporary architecture. The articles of our issue show the present and the future of architecture for fitness. We present a topical collection with a wide geographical range, including the Irkutsk Agglomeration, Tomsk, Krasnodar, sports in the Moscow Palace of Young Pioneers, and the anthology of the top foreign sports venues.

  19. Critical Mass

    CERN Multimedia

    AUTHOR|(CDS)2070299

    2017-01-01

    Critical Mass is a cycling event typically held on the last Friday of every month; its purpose is not usually formalized beyond the direct action of meeting at a set location and time and traveling as a group through city or town streets on bikes. The event originated in 1992 in San Francisco; by the end of 2003, the event was being held in over 300 cities around the world. At CERN it is held once a year in conjunction with the national Swiss campaing "Bike to work".

  20. Mass Customization Services

    DEFF Research Database (Denmark)

    Friedrich, Gerhard

    Topics of the IMCM’08 & PETO’08 and this book are: Mass customization in service, mass customizing financial services, mass customization in supply networks, implementation issues in logistics, product life cycle and mass customization. The research field of mass customization is more than 15 years...

  1. Neutrino mass matrix

    International Nuclear Information System (INIS)

    Strobel, E.L.

    1985-01-01

    Given the many conflicting experimental results, examination is made of the neutrino mass matrix in order to determine possible masses and mixings. It is assumed that the Dirac mass matrix for the electron, muon, and tau neutrinos is similar in form to those of the quarks and charged leptons, and that the smallness of the observed neutrino masses results from the Gell-Mann-Ramond-Slansky mechanism. Analysis of masses and mixings for the neutrinos is performed using general structures for the Majorana mass matrix. It is shown that if certain tentative experimental results concerning the neutrino masses and mixing angles are confirmed, significant limitations may be placed on the Majorana mass matrix. The most satisfactory simple assumption concerning the Majorana mass matrix is that it is approximately proportional to the Dirac mass matrix. A very recent experimental neutrino mass result and its implications are discussed. Some general properties of matrices with structure similar to the Dirac mass matrices are discussed

  2. Galaxy Masses : A Review

    NARCIS (Netherlands)

    Courteau, Stephane; Cappellari, Michele; Jong, Roelof S. de; Dutton, Aaron A.; Koopmans, L.V.E.

    2013-01-01

    Galaxy masses play a fundamental role in our understanding of structure formation models. This review addresses the variety and reliability of mass estimators that pertain to stars, gas, and dark matter. The dierent sections on masses from stellar populations, dynamical masses of gas-rich and

  3. The Origin of Mass

    OpenAIRE

    森岡, 達史

    2013-01-01

    The quark-lepton mass problem and the ideas of mass protection are reviewed. The hierarchy problem and suggestions for its resolution, including Little Higgs models, are discussed. The Multiple Point Principle is introduced and used within the Standard Model to predict the top quark and Higgs particle masses. Mass matrix ans\\"{a}tze are considered; in particular we discuss the lightest family mass generation model, in which all the quark mixing angles are successfully expressed in terms of si...

  4. Heavy quark masses

    Science.gov (United States)

    Testa, Massimo

    1990-01-01

    In the large quark mass limit, an argument which identifies the mass of the heavy-light pseudoscalar or scalar bound state with the renormalized mass of the heavy quark is given. The following equation is discussed: m(sub Q) = m(sub B), where m(sub Q) and m(sub B) are respectively the mass of the heavy quark and the mass of the pseudoscalar bound state.

  5. Neutrino masses and oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Smirnov, A Yu

    1996-11-01

    New effects related to refraction of neutrinos in different media are reviewed and implication of the effects to neutrino mass and mixing are discussed. Patterns of neutrino masses and mixing implied by existing hints/bounds are described. Recent results on neutrino mass generation are presented. They include neutrino masses in SO(10) GUT`s and models with anomalous U(1), generation of neutrino mass via neutrino-neutralino mixing, models of sterile neutrino. (author). 95 refs, 9 figs.

  6. Alienation, Mass Society and Mass Culture.

    Science.gov (United States)

    Dam, Hari N.

    This monograph examines the nature of alienation in mass society and mass culture. Conceptually based on the "Gemeinschaft-Gesellschaft" paradigm of sociologist Ferdinand Tonnies, discussion traces the concept of alienation as it appears in the philosophies of Hegel, Marx, Kierkegaard, Sartre, and others. Dwight Macdonald's "A Theory of Mass…

  7. Some mass measurement problems

    International Nuclear Information System (INIS)

    Merritt, J.S.

    1976-01-01

    Concerning the problem of determining the thickness of a target, an uncomplicated approach is to measure its mass and area and take the quotient. This paper examines the mass measurement aspect of such an approach. (author)

  8. Biodiesel Mass Transit Demonstration

    Science.gov (United States)

    2010-04-01

    The Biodiesel Mass Transit Demonstration report is intended for mass transit decision makers and fleet managers considering biodiesel use. This is the final report for the demonstration project implemented by the National Biodiesel Board under a gran...

  9. Mass Customization Measurements Metrics

    DEFF Research Database (Denmark)

    Nielsen, Kjeld; Brunø, Thomas Ditlev; Jørgensen, Kaj Asbjørn

    2014-01-01

    A recent survey has indicated that 17 % of companies have ceased mass customizing less than 1 year after initiating the effort. This paper presents measurement for a company’s mass customization performance, utilizing metrics within the three fundamental capabilities: robust process design, choice...... navigation, and solution space development. A mass customizer when assessing performance with these metrics can identify within which areas improvement would increase competitiveness the most and enable more efficient transition to mass customization....

  10. Radiative Majorana Neutrino Masses

    OpenAIRE

    Hou, Wei-Shu; Wong, Gwo-Guang

    1994-01-01

    We present new radiative mechanisms for generating Majorana neutrino masses, within an extension of the standard model that successfully generates radiative charged lepton masses, order by order, from heavy sequential leptons. Only the new sequential neutral lepton has a right-handed partner, and its Majorana mass provides the seed for Majorana neutrino mass generation. Saturating the cosmological bound of $50$ eV with $m_{\

  11. Asteroids mass determination

    International Nuclear Information System (INIS)

    Hoffmann, M.

    1989-01-01

    Basic methods for asteroid mass determinations and their errors are discussed. New results and some current developments in the astrometric method are reviewed. New methods and techniques, such as electronic imaging, radar ranging and space probes are becoming important for asteroid mass determinations. Mass and density estimations on rotational properties and possible satelites are also discussed

  12. Fourier Transform Mass Spectrometry.

    Science.gov (United States)

    Gross, Michael L.; Rempel, Don L.

    1984-01-01

    Discusses the nature of Fourier transform mass spectrometry and its unique combination of high mass resolution, high upper mass limit, and multichannel advantage. Examines its operation, capabilities and limitations, applications (ion storage, ion manipulation, ion chemistry), and future applications and developments. (JN)

  13. Scalar quarkonium masses

    International Nuclear Information System (INIS)

    Lee, W.; Weingarten, D.

    1996-01-01

    We evaluate the valence approximation to the mass of scalar quarkonium for a range of different parameters. Our results strongly suggest that the infinite volume continuum limit of the mass of ss scalar quarkonium lies well below the mass of f J (1710). The resonance f 0 (1500) appears to the best candidate for ss scalar quarkonium. (orig.)

  14. What masses for Cepheids

    International Nuclear Information System (INIS)

    Davis, C.G.

    To understand the evolution of giant stars, it is important to pin down the masses for Cepheids. The 7- to 10-day bump Cepheids imply lower than evolutionary mass (60%). Recent theoretical work, though, indicates that for Cepheids with periods of 15 to 16 days, the best understanding of the light curves results from using evolutionary masses

  15. On Defining Mass

    Science.gov (United States)

    Hecht, Eugene

    2011-01-01

    Though central to any pedagogical development of physics, the concept of mass is still not well understood. Properly defining mass has proven to be far more daunting than contemporary textbooks would have us believe. And yet today the origin of mass is one of the most aggressively pursued areas of research in all of physics. Much of the excitement surrounding the Large Hadron Collider at CERN is associated with discovering the mechanism responsible for the masses of the elementary particles. This paper will first briefly examine the leading definitions, pointing out their shortcomings. Then, utilizing relativity theory, it will propose—for consideration by the community of physicists—a conceptual definition of mass predicated on the more fundamental concept of energy, more fundamental in that everything that has mass has energy, yet not everything that has energy has mass.

  16. Fourier Transform Mass Spectrometry

    Science.gov (United States)

    Scigelova, Michaela; Hornshaw, Martin; Giannakopulos, Anastassios; Makarov, Alexander

    2011-01-01

    This article provides an introduction to Fourier transform-based mass spectrometry. The key performance characteristics of Fourier transform-based mass spectrometry, mass accuracy and resolution, are presented in the view of how they impact the interpretation of measurements in proteomic applications. The theory and principles of operation of two types of mass analyzer, Fourier transform ion cyclotron resonance and Orbitrap, are described. Major benefits as well as limitations of Fourier transform-based mass spectrometry technology are discussed in the context of practical sample analysis, and illustrated with examples included as figures in this text and in the accompanying slide set. Comparisons highlighting the performance differences between the two mass analyzers are made where deemed useful in assisting the user with choosing the most appropriate technology for an application. Recent developments of these high-performing mass spectrometers are mentioned to provide a future outlook. PMID:21742802

  17. The Point Mass Concept

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2011-04-01

    Full Text Available A point-mass concept has been elaborated from the equations of the gravitational field. One application of these deductions results in a black hole configuration of the Schwarzschild type, having no electric charge and no angular momentum. The critical mass of a gravitational collapse with respect to the nuclear binding energy is found to be in the range of 0.4 to 90 solar masses. A second application is connected with the spec- ulation about an extended symmetric law of gravitation, based on the options of positive and negative mass for a particle at given positive energy. This would make masses of equal polarity attract each other, while masses of opposite polarity repel each other. Matter and antimatter are further proposed to be associated with the states of positive and negative mass. Under fully symmetric conditions this could provide a mechanism for the separation of antimatter from matter at an early stage of the universe.

  18. The Point Mass Concept

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2011-04-01

    Full Text Available A point-mass concept has been elaborated from the equations of the gravitational field. One application of these deductions results in a black hole configuration of the Schwarzschild type, having no electric charge and no angular momentum. The critical mass of a gravitational collapse with respect to the nuclear binding energy is found to be in the range of 0.4 to 90 solar masses. A second application is connected with the speculation about an extended symmetric law of gravitation, based on the options of positive and negative mass for a particle at given positive energy. This would make masses of equal polarity attract each other, while masses of opposite polarity repel each other. Matter and antimatter are further proposed to be associated with the states of positive and negative mass. Under fully symmetric conditions this could provide a mechanism for the separation of antimatter from matter at an early stage of the universe.

  19. Is Mass Customization Sustainable?

    DEFF Research Database (Denmark)

    Petersen, Thomas Ditlev; Jørgensen, Kaj Asbjørn; Nielsen, Kjeld

    2011-01-01

    Mass customizers are like other companies currently experiencing an increasing customer demand for environmentally sustainable products as well as an increasingly strict legislation regarding environmental sustainability. This paper addresses the issue whether the concepts mass customization...... and sustainability are fundamentally compatible by asking the question: can a mass customized product be sustainable? Several factors could indicate that mass customized products are less sustainable than standardized products; however other factors suggest the opposite. This paper explores these factors during...... three life cycle phases for a product: Production, Use and End of Life. It is concluded that there is not an unambiguous causal relationship between mass customization and sustainability; however several factors unique to mass customized products are essential to consider during product and process...

  20. Main sequence mass loss

    International Nuclear Information System (INIS)

    Brunish, W.M.; Guzik, J.A.; Willson, L.A.; Bowen, G.

    1987-01-01

    It has been hypothesized that variable stars may experience mass loss, driven, at least in part, by oscillations. The class of stars we are discussing here are the δ Scuti variables. These are variable stars with masses between about 1.2 and 2.25 M/sub θ/, lying on or very near the main sequence. According to this theory, high rotation rates enhance the rate of mass loss, so main sequence stars born in this mass range would have a range of mass loss rates, depending on their initial rotation velocity and the amplitude of the oscillations. The stars would evolve rapidly down the main sequence until (at about 1.25 M/sub θ/) a surface convection zone began to form. The presence of this convective region would slow the rotation, perhaps allowing magnetic braking to occur, and thus sharply reduce the mass loss rate. 7 refs

  1. MassTRIX: mass translator into pathways.

    Science.gov (United States)

    Suhre, Karsten; Schmitt-Kopplin, Philippe

    2008-07-01

    Recent technical advances in mass spectrometry (MS) have brought the field of metabolomics to a point where large numbers of metabolites from numerous prokaryotic and eukaryotic organisms can now be easily and precisely detected. The challenge today lies in the correct annotation of these metabolites on the basis of their accurate measured masses. Assignment of bulk chemical formula is generally possible, but without consideration of the biological and genomic context, concrete metabolite annotations remain difficult and uncertain. MassTRIX responds to this challenge by providing a hypothesis-driven approach to high precision MS data annotation. It presents the identified chemical compounds in their genomic context as differentially colored objects on KEGG pathway maps. Information on gene transcription or differences in the gene complement (e.g. samples from different bacterial strains) can be easily added. The user can thus interpret the metabolic state of the organism in the context of its potential and, in the case of submitted transcriptomics data, real enzymatic capacities. The MassTRIX web server is freely accessible at http://masstrix.org.

  2. Glycomics using mass spectrometry

    OpenAIRE

    Wuhrer, Manfred

    2013-01-01

    Mass spectrometry plays an increasingly important role in structural glycomics. This review provides an overview on currently used mass spectrometric approaches such as the characterization of glycans, the analysis of glycopeptides obtained by proteolytic cleavage of proteins and the analysis of glycosphingolipids. The given examples are demonstrating the application of mass spectrometry to study glycosylation changes associated with congenital disorders of glycosylation, lysosomal storage di...

  3. Mass spectrometry in oceanography

    International Nuclear Information System (INIS)

    Aggarwal, Suresh K.

    2000-01-01

    Mass spectrometry plays an important role in oceanography for various applications. Different types of inorganic as well as organic mass spectrometric techniques are being exploited world-wide to understand the different aspects of marine science, for palaeogeography, palaeoclimatology and palaeoecology, for isotopic composition and concentrations of different elements as well as for speciation studies. The present paper reviews some of the applications of atomic mass spectrometric techniques in the area of oceanography

  4. Large mass storage facility

    International Nuclear Information System (INIS)

    Peskin, A.M.

    1978-01-01

    The report of a committee to study the questions surrounding possible acquisition of a large mass-storage device is presented. The current computing environment at BNL and justification for an online large mass storage device are briefly discussed. Possible devices to meet the requirements of large mass storage are surveyed, including future devices. The future computing needs of BNL are prognosticated. 2 figures, 4 tables

  5. The origin of mass

    International Nuclear Information System (INIS)

    Cashmore, R.; Sutton, C.

    1992-01-01

    The existence of mass in the Universe remains unexplained but recent high-energy experiments, described in this article, are close to testing the most plausible explanation for the masses of fundamental particles, which may, in turn, lead to a clearer understanding of mass on the macro-scale. The Standard Model includes the concept of the Higgs mechanism which endows particles with mass. Actual evidence for the existence of the postulated particle known as the Higgs boson would lead to confirmation of the theory and efforts to detect it at CERN are complex and determined. (UK)

  6. MassAI

    DEFF Research Database (Denmark)

    2011-01-01

    A software tool for general analysis and data-mining of mass-spectrometric datasets. The program features a strong emphasis on scan-by-scan identification and results-transparency. MassAI also accommodates residue level analysis of labelled runs, e.g. HDX.......A software tool for general analysis and data-mining of mass-spectrometric datasets. The program features a strong emphasis on scan-by-scan identification and results-transparency. MassAI also accommodates residue level analysis of labelled runs, e.g. HDX....

  7. Masses of Cepheids

    International Nuclear Information System (INIS)

    Fox, A.N.

    1980-01-01

    About ten years ago it became apparent that the masses of Cepheids predicted from the theory of stellar evolution were larger than those predicted by pulsation theory. This mass anomaly for the classical Cepheids was displayed by Christy (1968) and Stobie (1969a,b,c) using nonlinear hydrodynamic calculations and by Cogan (1970) using linear theory. Rodgers (1970) has also discussed the several mass anomalies in some detail. These mass anomalies, and some others to be discussed, have not yet been completely resolved, but many of the discrepancies have been alleviated mostly by an increase in the Cepheid luminosities and a decrease in their surface temperatures

  8. Cyclotrons as mass spectrometers

    International Nuclear Information System (INIS)

    Clark, D.J.

    1984-04-01

    The principles and design choices for cyclotrons as mass spectrometers are described. They are illustrated by examples of cyclotrons developed by various groups for this purpose. The use of present high energy cyclotrons for mass spectrometry is also described. 28 references, 12 figures

  9. ABSOLUTE NEUTRINO MASSES

    DEFF Research Database (Denmark)

    Schechter, J.; Shahid, M. N.

    2012-01-01

    We discuss the possibility of using experiments timing the propagation of neutrino beams over large distances to help determine the absolute masses of the three neutrinos.......We discuss the possibility of using experiments timing the propagation of neutrino beams over large distances to help determine the absolute masses of the three neutrinos....

  10. Systematics of quark mass

    International Nuclear Information System (INIS)

    Frampton, P.H.; Jarlskog, C.

    1985-01-01

    It is shown that the quark mass matrices in the Standard Electroweak Model satisfy the empirical relation M = M 1 + Ψ(Λ 2 ), where M(M sp (')) refers to the mass matrix of the charge 2/3(-1/3) quarks normalized to the largest eigenvalue, m sub (t)(m sub (b)), and Λ = V sub (us) = 0.22

  11. Measurements of neutrino mass

    International Nuclear Information System (INIS)

    Robertson, R.G.H.

    1985-01-01

    Direct experimental information of neutrino mass as derived from the study of nuclear and elementary-particle weak decays is reviewed. Topics include tritium beta decay; the 3 He-T mass difference; electron capture decay of 163 Ho and 158 Tb; and limits on massive neutrinos from cosmology. 38 references

  12. The Origin of Mass

    Energy Technology Data Exchange (ETDEWEB)

    Giese, Albrecht

    2010-07-01

    The world of physics presently looks to the LHC (CERN), where many expect the Higgs boson to be found. The Higgs is supposed to (partly) explain the cause of mass. There are indications that neither the Higgs nor Supersymmetric Particles will be found. In order to understand mass, the Higgs is not needed. Inertial mass is caused by a fundamental process. Binding fields propagate at the finite speed of light. An inevitable consequence is that every expanded object has an inertial behaviour, even if the constituents of the object are mass-less. To explain the mass of elementary particles, we have to accept that these particles are expanded. This is on the one hand in conflict with the concept of present physics; on the other hand it is in no conflict with any experiment. And it conforms to the analysis of Schroedinger with respect to the Dirac function of the electron. The corresponding particle model explains particle properties, like the magnetic moment (and therefore also the Bohr Magneton) and the constancy of the spin, correctly without any use of QM. Also the dynamic properties of mass, i.e. the relativistic increase of mass at motion and the mass-energy-relation, follow in a straight way from this concept.

  13. Mass spectrometers in medicine

    International Nuclear Information System (INIS)

    Bushman, J.A.

    1975-01-01

    This paper describes how the mass spectrometer enables true lung function, namely the exchange of gases between the environment and the organism, to be measured. This has greatly improved the understanding of respiratory disease and the latest generation of respiratory mass spectrometers will do much to increase the application of the technique. (author)

  14. Mass of AC Andromedae

    International Nuclear Information System (INIS)

    King, D.S.; Cox, A.N.; Hodson, S.W.

    1975-01-01

    Calculations indicate that AC Andromedae is population I rather than population II. A mass and radius for this star are calculated using a new set of opacities for the Kippenhahn Ia mixture. It is concluded that the mass is too high for an ordinary RR Lyrae star. (BJG)

  15. Mass preserving image registration

    DEFF Research Database (Denmark)

    Gorbunova, Vladlena; Sporring, Jon; Lo, Pechin Chien Pau

    2010-01-01

    The paper presents results the mass preserving image registration method in the Evaluation of Methods for Pulmonary Image Registration 2010 (EMPIRE10) Challenge. The mass preserving image registration algorithm was applied to the 20 image pairs. Registration was evaluated using four different...

  16. Elbow mass flow meter

    Science.gov (United States)

    McFarland, A.R.; Rodgers, J.C.; Ortiz, C.A.; Nelson, D.C.

    1994-08-16

    The present invention includes a combination of an elbow pressure drop generator and a shunt-type mass flow sensor for providing an output which gives the mass flow rate of a gas that is nearly independent of the density of the gas. For air, the output is also approximately independent of humidity. 3 figs.

  17. Miniature mass analyzer

    CERN Document Server

    Cuna, C; Lupsa, N; Cuna, S; Tuzson, B

    2003-01-01

    The paper presents the concept of different mass analyzers that were specifically designed as small dimension instruments able to detect with great sensitivity and accuracy the main environmental pollutants. The mass spectrometers are very suited instrument for chemical and isotopic analysis, needed in environmental surveillance. Usually, this is done by sampling the soil, air or water followed by laboratory analysis. To avoid drawbacks caused by sample alteration during the sampling process and transport, the 'in situ' analysis is preferred. Theoretically, any type of mass analyzer can be miniaturized, but some are more appropriate than others. Quadrupole mass filter and trap, magnetic sector, time-of-flight and ion cyclotron mass analyzers can be successfully shrunk, for each of them some performances being sacrificed but we must know which parameters are necessary to be kept unchanged. To satisfy the miniaturization criteria of the analyzer, it is necessary to use asymmetrical geometries, with ion beam obl...

  18. Proton mass decomposition

    Science.gov (United States)

    Yang, Yi-Bo; Chen, Ying; Draper, Terrence; Liang, Jian; Liu, Keh-Fei

    2018-03-01

    We report the results on the proton mass decomposition and also on the related quark and glue momentum fractions. The results are based on overlap valence fermions on four ensembles of Nf = 2 + 1 DWF configurations with three lattice spacings and volumes, and several pion masses including the physical pion mass. With 1-loop pertur-bative calculation and proper normalization of the glue operator, we find that the u, d, and s quark masses contribute 9(2)% to the proton mass. The quark energy and glue field energy contribute 31(5)% and 37(5)% respectively in the MS scheme at µ = 2 GeV. The trace anomaly gives the remaining 23(1)% contribution. The u, d, s and glue momentum fractions in the MS scheme are consistent with the global analysis at µ = 2 GeV.

  19. Linear mass reflectron

    International Nuclear Information System (INIS)

    Mamyrin, B.A.; Shmikk, D.V.

    1979-01-01

    A description and operating principle of a linear mass reflectron with V-form trajectory of ion motion -a new non-magnetic time-of-flight mass spectrometer with high resolution are presented. The ion-optical system of the device consists of an ion source with ionization by electron shock, of accelerating gaps, reflector gaps, a drift space and ion detector. Ions move in the linear mass refraction along the trajectories parallel to the axis of the analyzer chamber. The results of investigations into the experimental device are given. With an ion drift length of 0.6 m the device resolution is 1200 with respect to the peak width at half-height. Small-sized mass spectrometric transducers with high resolution and sensitivity may be designed on the base of the linear mass reflectron principle

  20. Top Quark Mass

    CERN Document Server

    Mulders, Martijn

    2016-01-01

    Ever since the discovery of the top quark at the Tevatron collider in 1995 the measurement of its mass has been a high priority. As one of the fundamental parameters of the Standard Theory of particle physics, the precise value of the top quark mass together with other inputs provides a test for the self-consistency of the theory, and has consequences for the stability of the Higgs field that permeates the Universe. In this review I will briefly summarize the experimental techniques used at the Tevatron and the LHC experiments throughout the years to measure the top quark mass with ever improving accuracy, and highlight the recent progress in combining all measurements in a single world average combination. As experimental measurements became more precise, the question of their theoretical interpretation has become important. The difficulty of relating the measured quantity to the fundamental top mass parameter has inspired alternative measurement methods that extract the top mass in complementary ways. I wil...

  1. Eosinophilic Angiocentric Fibrosis as a Stenosing Lesion in the Subglottis

    Directory of Open Access Journals (Sweden)

    Ivan Keogh

    2017-01-01

    Full Text Available Subglottic Eosinophilic Angiocentric Fibrosis (EAF is an extremely rare disease of an elusive aetiology. It is chronically progressive benign condition that causes narrowing of the subglottic region leading to dysphonia and airway compromise. The diagnosis is historical and imaging is nonspecific. We report a case xc of 56-year-old lady referred to our institution with globus sensation, hoarseness, and mild stridor. Incidental subglottic mass was found at time of diagnostic microlaryngoscopy and biopsy confirmed subglottic EAF. All laboratory investigations were unremarkable. Lesion was removed with laryngeal microdebrider and three courses of intravenous dexamethasone were administered. Patient’s postoperative period was uneventful and had remained disease free for 1 year. To date, no consensus has been reached on the optimal treatment of subglottic EAF. We recommend regular follow-up to detect early recurrence.

  2. Origins of mass

    Science.gov (United States)

    Wilczek, Frank

    2012-10-01

    Newtonian mechanics posited mass as a primary quality of matter, incapable of further elucidation. We now see Newtonian mass as an emergent property. That mass-concept is tremendously useful in the approximate description of baryon-dominated matter at low energy — that is, the standard "matter" of everyday life, and of most of science and engineering — but it originates in a highly contingent and non-trivial way from more basic concepts. Most of the mass of standard matter, by far, arises dynamically, from back-reaction of the color gluon fields of quantum chromodynamics (QCD). Additional quantitatively small, though physically crucial, contributions come from the intrinsic masses of elementary quanta (electrons and quarks). The equations for massless particles support extra symmetries — specifically scale, chiral, and gauge symmetries. The consistency of the standard model relies on a high degree of underlying gauge and chiral symmetry, so the observed non-zero masses of many elementary particles ( W and Z bosons, quarks, and leptons) requires spontaneous symmetry breaking. Superconductivity is a prototype for spontaneous symmetry breaking and for mass-generation, since photons acquire mass inside superconductors. A conceptually similar but more intricate form of all-pervasive ( i.e. cosmic) superconductivity, in the context of the electroweak standard model, gives us a successful, economical account of W and Z boson masses. It also allows a phenomenologically successful, though profligate, accommodation of quark and lepton masses. The new cosmic superconductivity, when implemented in a straightforward, minimal way, suggests the existence of a remarkable new particle, the so-called Higgs particle. The mass of the Higgs particle itself is not explained in the theory, but appears as a free parameter. Earlier results suggested, and recent observations at the Large Hadron Collider (LHC) may indicate, the actual existence of the Higgs particle, with mass m H

  3. Dynamical Mass Generation.

    Science.gov (United States)

    Mendel Horwitz, Roberto Ruben

    1982-03-01

    In the framework of the Glashow-Weinberg-Salem model without elementary scalar particles, we show that masses for fermions and intermediate vector bosons can be generated dynamically. The mechanism is the formation of fermion-antifermion pseudoscalar bound states of zero total four momentum, which form a condensate in the physical vacuum. The force responsible for the binding is the short distance part of the net Coulomb force due to photon and Z exchange. Fermions and bosons acquire masses through their interaction with this condensate. The neutrinos remain massless because their righthanded components have no interactions. Also the charge -1/3 quarks remain massless because the repulsive force from the Z exchange dominates over the Coulomb force. To correct this, we propose two possible modifications to the theory. One is to cut off the Z exchange at very small distances, so that all fermions except the neutrinos acquire masses, which are then, purely electromagnetic in origin. The other is to introduce an additional gauge boson that couples to all quarks with a pure vector coupling. To make this vector boson unobservable at usual energies, at least two new fermions must couple to it. The vector boson squared masses receive additive contributions from all the fermion squared masses. The photon remains massless and the masses of the Z and W('(+OR -)) bosons are shown to be related through the Weinberg angle in the conventional way. Assuming only three families of fermions, we obtain estimates for the top quark mass.

  4. Probabilistic Mass Growth Uncertainties

    Science.gov (United States)

    Plumer, Eric; Elliott, Darren

    2013-01-01

    Mass has been widely used as a variable input parameter for Cost Estimating Relationships (CER) for space systems. As these space systems progress from early concept studies and drawing boards to the launch pad, their masses tend to grow substantially, hence adversely affecting a primary input to most modeling CERs. Modeling and predicting mass uncertainty, based on historical and analogous data, is therefore critical and is an integral part of modeling cost risk. This paper presents the results of a NASA on-going effort to publish mass growth datasheet for adjusting single-point Technical Baseline Estimates (TBE) of masses of space instruments as well as spacecraft, for both earth orbiting and deep space missions at various stages of a project's lifecycle. This paper will also discusses the long term strategy of NASA Headquarters in publishing similar results, using a variety of cost driving metrics, on an annual basis. This paper provides quantitative results that show decreasing mass growth uncertainties as mass estimate maturity increases. This paper's analysis is based on historical data obtained from the NASA Cost Analysis Data Requirements (CADRe) database.

  5. Top quark mass measurement

    International Nuclear Information System (INIS)

    Maki, Tuula; Helsinki Inst. of Phys.; Helsinki U. of Tech.

    2008-01-01

    The top quark is the heaviest elementary particle. Its mass is one of the fundamental parameters of the standard model of particle physics, and an important input to precision electroweak tests. This thesis describes three measurements of the top-quark mass in the dilepton decay channel. The dilepton events have two neutrinos in the final state; neutrinos are weakly interacting particles that cannot be detected with a multipurpose experiment. Therefore, the signal of dilepton events consists of a large amount of missing energy and momentum carried off by the neutrinos. The top-quark mass is reconstructed for each event by assuming an additional constraint from a top mass independent distribution. Template distributions are constructed from simulated samples of signal and background events, and parameterized to form continuous probability density functions. The final top-quark mass is derived using a likelihood fit to compare the reconstructed top mass distribution from data to the parameterized templates. One of the analyses uses a novel technique to add top mass information from the observed number of events by including a cross-section-constraint in the likelihood function. All measurements use data samples collected by the CDF II detector

  6. Organ mass measurements

    International Nuclear Information System (INIS)

    Kawamura, H.

    1998-01-01

    The term, anatomical measurements, in the context of this Co-ordinated Research Programme refers to measurements of masses of internal organs, although the human body is composed of internal organs and tissues such as skeleton, muscle, skin and adipose. The mass of an organ containing a radionuclide (source organ), and the mass of a target organ which absorbs energy of the radiation, are essential parameters in the ICRP dosimetric model derived from the MIRD method. Twelve specific organs of interest were proposed at the Coordinated Research Programme Project Formulation Meeting (PFM) in 1988. A slightly different set of thirteen organs with potential significance for radiation protection were selected for study at the Research Co-ordination Meeting held at the Bhabha Atomic Research Centre in 1991. The dimensions of the organs could also be useful information, but were considered unimportant for internal dose assessment. Due to the strong concern about the unified method for collecting organ mass data at the PFM, a guide-line was established stressing the need for organ data from subjects that were healthy and normal, at least until shortly before death, or from sudden death cases, following the Japanese experience. In this report, masses of nine to thirteen organs are presented from seven participating countries. Three participants have also reported the organ masses as fractions of the total body mass

  7. Masses of supernova progenitors

    International Nuclear Information System (INIS)

    Tinsley, B.M.

    1977-01-01

    The possible nature and masses of supernovae progenitors, and the bearing of empirical results on some unsolved theoretical problems concerning the origin of supernovae, are discussed. The author concentrates on two main questions: what is the lower mass limit for stars to die explosively and what stars initiate type I supernovae. The evidence considered includes local supernova rates, empirical estimates of msub(w) (the upper mass limit for death as a white dwarf), the distributions of supernovae among stellar populations in galaxies and the colors of supernova producing galaxies. (B.D.)

  8. Photon mass experiment

    International Nuclear Information System (INIS)

    Crandall, R.E.

    1983-01-01

    A Coulomb null experiment is described that enables physics students to obtain rigorous upper bounds on photon mass. The experimenter searches for subnanovolt signals that would escape a closed shell were photon mass to be positive. The approach can be adapted for several college levels. At the simplest level, a ''miniature'' low-cost experiment allows a student to verify the exponent ''-2'' in Coulomb's law to eight or more decimal places. An advanced student given a full-size apparatus (at greater cost) can obtain mass bounds very close to the established laboratory limit

  9. Masses of Formal Philosophy

    DEFF Research Database (Denmark)

    Masses of Formal Philosophy is an outgrowth of Formal Philosophy. That book gathered the responses of some of the most prominent formal philosophers to five relatively open and broad questions initiating a discussion of metaphilosophical themes and problems surrounding the use of formal methods i...... in philosophy. Including contributions from a wide range of philosophers, Masses of Formal Philosophy contains important new responses to the original five questions.......Masses of Formal Philosophy is an outgrowth of Formal Philosophy. That book gathered the responses of some of the most prominent formal philosophers to five relatively open and broad questions initiating a discussion of metaphilosophical themes and problems surrounding the use of formal methods...

  10. Minimum critical mass systems

    International Nuclear Information System (INIS)

    Dam, H. van; Leege, P.F.A. de

    1987-01-01

    An analysis is presented of thermal systems with minimum critical mass, based on the use of materials with optimum neutron moderating and reflecting properties. The optimum fissile material distributions in the systems are obtained by calculations with standard computer codes, extended with a routine for flat fuel importance search. It is shown that in the minimum critical mass configuration a considerable part of the fuel is positioned in the reflector region. For 239 Pu a minimum critical mass of 87 g is found, which is the lowest value reported hitherto. (author)

  11. Neutrino mass experiments

    International Nuclear Information System (INIS)

    Robertson, R.G.H.

    1989-01-01

    The current status of the experimental search for neutrino mass is reviewed, with emphasis on direct kinematic methods. Simpson and Hime report finding new evidence for a 17-keV neutrino in the β decay of 3 H and 35 S. The situation concerning the electron neutrino mass as measured in tritium beta decay has not changed significantly in the last two years. We discuss the ''model independent'' lower limit of 17 eV obtained by the ITEP group in light of existing data on the 3 H-- 3 He mass difference. 42 refs., 1 fig., 1 tab

  12. High mass planets and low mass stars

    International Nuclear Information System (INIS)

    Stevenson, D.J.

    1986-01-01

    The paper on theoretical models of brown dwarf stars was presented to the workshop on ''Astrophysics of brown dwarfs'', Virginia, USA, 1985. The ingredients in the models i.e. equation of state, entropy and the infrared opacity are described. An analytical model is developed which is based on a polytrope (n = 3/4) but which neglects thermonuclear reactions. The model forms the basis of scaling laws for luminosity, mass, opacity and age. Complicating factors in brown dwarf evolution are also discussed. (U.K.)

  13. Very low mass stars

    International Nuclear Information System (INIS)

    Liebert, J.; Probst, R.G.

    1987-01-01

    This paper discusses several theoretical and observational topics involved in discovering and analyzing very low mass stellar objects below about 0.3 M circle, as well as their likely extension into the substellar range. The authors hereafter refer to these two classes of objects as VLM stars and brown dwarfs, respectively; collectively, they are called VLM objects. The authors outline recent theoretical work on low-mass stellar interiors and atmospheres, the determination of the hydrogen-burning mass limit, important dynamical evidence bearing on the expected numbers of such objects, and the expectations for such objects from star-formation theory. They focus on the properties of substellar objects near the stellar mass limit. Observational techniques used to discover and analyze VLM objects are summarized

  14. [Small renal mass].

    Science.gov (United States)

    Prokofiev, D; Kreutzer, N; Kress, A; Wissing, F; Pfeifer, H; Stolzenburg, J-U; Dietel, A; Schwalenberg, T; Do, M; Truß, M C

    2012-10-01

    The frequent application of ultrasound and radiological imaging for non-urological indications in recent years has resulted in an increase in the diagnosis of small renal masses. The treatment options for patients with a small renal mass include active surveillance, surgery (both open and minimally invasive) as well as ablative techniques. As there is a risk for metastatic spread even in small renal masses surgical extirpation remains the treatment of choice in most patients. Ablative procedures, such as cryoablation and radiofrequency ablation are appropriate for old and multi-morbid patients who require active treatment of a small renal mass. Active surveillance is an alternative for high-risk patients. Meticulous patient selection by the urologist and patient preference will determine the choice of treatment option in the future.

  15. Arkitektur & Mass customization

    DEFF Research Database (Denmark)

    Ryborg Jørgensen, Thomas

    2007-01-01

    Publikationens ambition er at udrede og give indblik i produktindustriens seneste udvikling med forretnings- og produktionsstrategien Mass Customization, og dermed en indgang til de muligheder og problemer der knytter sig til implementering af disse eller tilsvarende strategier i byggebranchen, og...

  16. Mass Psychogenic Illness

    Science.gov (United States)

    ... Outbreaks of mass psychogenic illness show us how stress affects us. Think of how stage fright can cause nausea, shortness of breath, headache, dizziness, a racing heart, a stomachache, or diarrhea. ...

  17. Body Mass Index Table

    Science.gov (United States)

    ... Families ( We Can! ) Health Professional Resources Body Mass Index Table 1 for BMI greater than 35, go ... Health Information Email Alerts Jobs and Careers Site Index About NHLBI National Institute of Health Department of ...

  18. Relative feather mass indices: are feather masses needed to ...

    African Journals Online (AJOL)

    Relative feather mass indices: are feather masses needed to estimate the percentage of new feather mass grown for moult regression models? ... As an alternative, it is here tested if feather mass indices may be sufficient replacements for species-specific feather masses. Thirty-five species of birds with known primary ...

  19. Leptogenesis and neutrino masses

    International Nuclear Information System (INIS)

    Pluemacher, M.

    2004-01-01

    Thermal leptogenesis explains the baryon asymmetry of the universe by the out-of-equilibrium decays of heavy right-handed neutrinos. In the minimal seesaw model this leads to interesting implications for light neutrino properties. In particular, quasi-degenerate light neutrino masses are incompatible with leptogenesis. An upper bound on light neutrino masses of 0.1 eV can be derived, which will be tested by forthcoming laboratory experiments and cosmology. (author)

  20. Ion Mass Determination

    DEFF Research Database (Denmark)

    2010-01-01

    An apparatus (100) is described for determining the mass of ions, the apparatus configured to hold a plasma (101 ) having a plasma potential. The apparatus (100) comprises an electrode (102) having a surface extending in a surface plane and an insulator (104) interfacing with the electrode (102......, and a processing unit (108) configured to interpret the detected impact locations in terms of the mass of the impacting ions....

  1. Mass of the photon

    International Nuclear Information System (INIS)

    Goldhaber, A.S.; Nieto, M.M.

    1976-01-01

    Several experiments are discussed for which results are equivalent to the catching and weighing of a photon. It is noted that none of the experiments has proved the rest mass to be zero and that such a proof may be impossible. It is shown by such experiments that the rest mass is less than the limit of accuracy of the experiment. These limits have approached ever closer to zero, and the most recent values are exceedingly small

  2. Forensic Mass Spectrometry

    Science.gov (United States)

    Hoffmann, William D.; Jackson, Glen P.

    2015-07-01

    Developments in forensic mass spectrometry tend to follow, rather than lead, the developments in other disciplines. Examples of techniques having forensic potential born independently of forensic applications include ambient ionization, imaging mass spectrometry, isotope ratio mass spectrometry, portable mass spectrometers, and hyphenated chromatography-mass spectrometry instruments, to name a few. Forensic science has the potential to benefit enormously from developments that are funded by other means, if only the infrastructure and personnel existed to adopt, validate, and implement the new technologies into casework. Perhaps one unique area in which forensic science is at the cutting edge is in the area of chemometrics and the determination of likelihood ratios for the evaluation of the weight of evidence. Such statistical techniques have been developed most extensively for ignitable-liquid residue analyses and isotope ratio analysis. This review attempts to capture the trends, motivating forces, and likely impact of developing areas of forensic mass spectrometry, with the caveat that none of this research is likely to have any real impact in the forensic community unless: (a) The instruments developed are turned into robust black boxes with red and green lights for positives and negatives, respectively, or (b) there are PhD graduates in the workforce who can help adopt these sophisticated techniques.

  3. Substernal Thyroid Masses

    Directory of Open Access Journals (Sweden)

    Mohamed A.H. Regal

    2010-10-01

    Full Text Available A thyroid mass, most often a non toxic colloid goiter or occasionally an adenoma, is not an unusual finding below the level of the thoracic inlet.1 In 1992 Creswell and Wells estimated that these tumors comprise 5.8% of all mediastinal lesions.1 There is no standard definition for thyroid glands extending below the thoracic inlet, but such masses descend from their original cervical location for more than 2 or 3 cm below the thoracic inlet, and are not truly primary tumors of the mediastinum. They preserve the connection between the thoracic and cervical portion and receive their blood supply from the neck.2,3 In 1940, the seminal report of Wakeley and Mulvany divided intrathoracic thyroid masses into 3 types; (1”Small substernal extension” of a mainly cervical mass, (2 “Partial” intrathoracic, in which the major portion of the mass is situated within the thorax, and (3”Complete” in which all of the mass lies within the thoracic cavity.

  4. Greenland Ice Sheet Mass Balance

    Science.gov (United States)

    Reeh, N.

    1984-01-01

    Mass balance equation for glaciers; areal distribution and ice volumes; estimates of actual mass balance; loss by calving of icebergs; hydrological budget for Greenland; and temporal variations of Greenland mass balance are examined.

  5. Fermion masses from dimensional reduction

    International Nuclear Information System (INIS)

    Kapetanakis, D.; Zoupanos, G.

    1990-01-01

    We consider the fermion masses in gauge theories obtained from ten dimensions through dimensional reduction on coset spaces. We calculate the general fermion mass matrix and we apply the mass formula in illustrative examples. (orig.)

  6. Fermion masses from dimensional reduction

    Energy Technology Data Exchange (ETDEWEB)

    Kapetanakis, D. (National Research Centre for the Physical Sciences Democritos, Athens (Greece)); Zoupanos, G. (European Organization for Nuclear Research, Geneva (Switzerland))

    1990-10-11

    We consider the fermion masses in gauge theories obtained from ten dimensions through dimensional reduction on coset spaces. We calculate the general fermion mass matrix and we apply the mass formula in illustrative examples. (orig.).

  7. Neutrino mass from Cosmology

    CERN Document Server

    Lesgourgues, Julien

    2012-01-01

    Neutrinos can play an important role in the evolution of the Universe, modifying some of the cosmological observables. In this contribution we summarize the main aspects of cosmological relic neutrinos and we describe how the precision of present cosmological data can be used to learn about neutrino properties, in particular their mass, providing complementary information to beta decay and neutrinoless double-beta decay experiments. We show how the analysis of current cosmological observations, such as the anisotropies of the cosmic microwave background or the distribution of large-scale structure, provides an upper bound on the sum of neutrino masses of order 1 eV or less, with very good perspectives from future cosmological measurements which are expected to be sensitive to neutrino masses well into the sub-eV range.

  8. Gaugino mass without singlets

    International Nuclear Information System (INIS)

    Giudice, Gian F.; Luty, Markus A.; Murayama, Hitoshi; Rattazzi, Riccardo

    1998-01-01

    In models with dynamical supersymmetry breaking in the hidden sector, the gaugino masses in the observable sector have been believed to be extremely suppressed (below 1 keV), unless there is a gauge singlet in the hidden sector with specific couplings to the observable sector gauge multiplets. We point out that there is a pure supergravity contribution to gaugino masses at the quantum level arising from the superconformal anomaly. Our results are valid to all orders in perturbation theory and are related to the ''exact'' beta functions for soft terms. There is also an anomaly contribution to the A terms proportional to the beta function of the corresponding Yukawa coupling. The gaugino masses are proportional to the corresponding gauge beta functions, and so do not satisfy the usual GUT relations

  9. Diffusion and mass transfer

    CERN Document Server

    Vrentas, James S

    2013-01-01

    The book first covers the five elements necessary to formulate and solve mass transfer problems, that is, conservation laws and field equations, boundary conditions, constitutive equations, parameters in constitutive equations, and mathematical methods that can be used to solve the partial differential equations commonly encountered in mass transfer problems. Jump balances, Green’s function solution methods, and the free-volume theory for the prediction of self-diffusion coefficients for polymer–solvent systems are among the topics covered. The authors then use those elements to analyze a wide variety of mass transfer problems, including bubble dissolution, polymer sorption and desorption, dispersion, impurity migration in plastic containers, and utilization of polymers in drug delivery. The text offers detailed solutions, along with some theoretical aspects, for numerous processes including viscoelastic diffusion, moving boundary problems, diffusion and reaction, membrane transport, wave behavior, sedime...

  10. Keaton and the Masses

    DEFF Research Database (Denmark)

    Schmidt, Ulrik

    This paper explores conflicts between individual and mass and the process of 'massification' (i.e. the becoming of masses) as comic potential in Buster Keaton’s physical comedies. This comic potential is characterized by a person’s formalized and aestheticized de-individualization when confronted...... with tangible, non-human matter. As already indicated by Henri Bergson, de-individualization plays an important role in modern comedy in general. With his intense focus on massification, Keaton is not only one of the first, but also one of the most dedicated investigators of comic de-individualization by purely...... and thematics of the films and down to the comic details of each individual gag. The paper initiates by considering the complex relations in Keaton between gag and narrative with specific regard to the conflict between the individual and the masses. This leads to an exploration of the basic compositional...

  11. Baryogenesis and neutrino masses

    International Nuclear Information System (INIS)

    Peccei, R.D.

    1992-01-01

    The erasure of any preexisting B+L asymmetry in the universe in its late stages suggests that the B asymmetry observed today either originated at the electroweak scale or it arose from an original L asymmetry. For the latter case to be viable either neutrino masses are much below the eV scale or the L asymmetry itself is generated at an intermediate scale. Several features of the generation of a B asymmetry via an L asymmetry are discussed, including the interesting possibility that the present baryon asymmetry in the universe originates as a result of CP violating phases in the neutrino mass matrix

  12. Spontaneously broken mass

    International Nuclear Information System (INIS)

    Endlich, Solomon; Nicolis, Alberto; Penco, Riccardo

    2015-01-01

    The Galilei group involves mass as a central charge. We show that the associated superselection rule is incompatible with the observed phenomenology of superfluid helium 4: this is recovered only under the assumption that mass is spontaneously broken. This remark is somewhat immaterial for the real world, where the correct space-time symmetries are encoded by the Poincaré group, which has no central charge. Yet it provides an explicit example of how superselection rules can be experimentally tested. We elaborate on what conditions must be met for our ideas to be generalizable to the relativistic case of the integer/half-integer angular momentum superselection rule.

  13. Ambient ionization mass spectrometry

    International Nuclear Information System (INIS)

    Lebedev, A T

    2015-01-01

    Ambient ionization mass spectrometry emerged as a new scientific discipline only about ten years ago. A considerable body of information has been reported since that time. Keeping the sensitivity, performance and informativity of classical mass spectrometry methods, the new approach made it possible to eliminate laborious sample preparation procedures and triggered the development of miniaturized instruments to work directly in the field. The review concerns the theoretical foundations and design of ambient ionization methods. Their advantages and drawbacks, as well as prospects for application in chemistry, biology, medicine, environmetal analysis, etc., are discussed. The bibliography includes 194 references

  14. Atomic mass spectrometry

    International Nuclear Information System (INIS)

    Sanz-Medel, A.

    1997-01-01

    The elemental inorganic analysis seems to be dominated today by techniques based on atomic spectrometry. After an evaluation of advantages and limitations of using mass analysers (ion detectors) versus conventional photomultipliers (photon detector) a brief review of the more popular techniques of the emerging Atomic Mass spectrometry is carried out. Their huge potential for inorganic trace analysis is such that in the future we could well witness how this end of the century and millennium marked the fall of the photons empire in Analytical Atomic Spectrometry. (Author)

  15. Fermion masses and multiplicity

    International Nuclear Information System (INIS)

    Ramond, P.

    1986-01-01

    A general survey and analysis of fermion masses is presented in terms of both the known low energy gauge structure and of the simplest GUT structure. The replication of fermion families is discussed in the context of possible family group structures. Sample family gauge groups are presented in the cases of three and four chiral families, using ABJ and Witten anomalies to restrict the maximal gauged family group. The possible relevance of the family group to the fermion mass hierarchy is discussed in the context of various models. (author)

  16. Towards absolute neutrino masses

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, Petr [Kellogg Radiation Laboratory 106-38, Caltech, Pasadena, CA 91125 (United States)

    2007-06-15

    Various ways of determining the absolute neutrino masses are briefly reviewed and their sensitivities compared. The apparent tension between the announced but unconfirmed observation of the 0{nu}{beta}{beta} decay and the neutrino mass upper limit based on observational cosmology is used as an example of what could happen eventually. The possibility of a 'nonstandard' mechanism of the 0{nu}{beta}{beta} decay is stressed and the ways of deciding which of the possible mechanisms is actually operational are described. The importance of the 0{nu}{beta}{beta} nuclear matrix elements is discussed and their uncertainty estimated.

  17. Question of neutrino mass

    International Nuclear Information System (INIS)

    Branco, G.C.; Senjanovic, G.

    1978-01-01

    We investigate the question of neutrino mass in theories in which neutrinos are four-component Dirac particles. Our analysis is done in the framework of left-right--symmetric theories. The requirement of calculability and natural smallness of neutrino mass leads to the following constraints: (i) left and right charged weak currents must be ''orthogonal'' to each other, and (ii) there should be no W/sub L/-W/sub R/ mixing at the three level. Finally, we exhibit a model in which, due to the existence of an unbroken symmetry of the total Lagrangian, the electron and muon neutrinos remain massless to all orders in perturbation theory

  18. Reconstructing Neutrino Mass Spectrum

    OpenAIRE

    Smirnov, A. Yu.

    1999-01-01

    Reconstruction of the neutrino mass spectrum and lepton mixing is one of the fundamental problems of particle physics. In this connection we consider two central topics: (i) the origin of large lepton mixing, (ii) possible existence of new (sterile) neutrino states. We discuss also possible relation between large mixing and existence of sterile neutrinos.

  19. Miniaturization and Mass Spectrometry

    NARCIS (Netherlands)

    le Gac, S.; le Gac, Severine; van den Berg, Albert; van den Berg, A.; Unknown, [Unknown

    2009-01-01

    With this book we want to illustrate how two quickly growing fields of instrumentation and technology, both applied to life sciences, mass spectrometry and microfluidics (or microfabrication) naturally came to meet at the end of the last century and how this marriage impacts on several types of

  20. The Disk Mass Project

    NARCIS (Netherlands)

    Verheijen, Marc A. W.; Bershady, Matthew A.; Swaters, Rob A.; Andersen, David R.; Westfall, Kyle B.; de Jong, Roelof Sybe

    2007-01-01

    Little is known about the content and distribution of dark matter in spiral galaxies. To break the degeneracy in galaxy rotation curve decompositions, which allows a wide range of dark matter halo density profiles, an independent measure of the mass surface density of stellar disks is needed. Here,

  1. Mass of 48K

    International Nuclear Information System (INIS)

    Weisser, D.C.; Zeller, A.F.; Ophel, T.R.; Hebbard, D.F.

    1978-08-01

    The mass excess of 48 K was measured to be -32.117 +or- .027 MeV using the 48 Ca( 7 Li, 7 Be) 48 K reaction at 52 MeV. The result is consistent with predictions and a previous less accurate measurement. There is evidence for an excited state in 48 K at 0.58 MeV

  2. Processes of Mass Communication.

    Science.gov (United States)

    Channey, David

    This sociological treatment of mass communications analysis first discusses the theories of audience behavior, then turns to the organization of media production, and closes with a study of performance. The book covers audience needs and gratifications, the history of British press and broadcasting results of systems of media distribution, the…

  3. Emotions and Mass Atrocity

    DEFF Research Database (Denmark)

    Lang, Johannes

    social and political forces, deeply involved in the history of mass violence. Drawing on recent insights from philosophy, psychology, history, and the social sciences, this volume examines the emotions of perpetrators, victims, and bystanders. Editors Thomas Brudholm and Johannes Lang have brought...

  4. Analytical mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    This 43rd Annual Summer Symposium on Analytical Chemistry was held July 24--27, 1990 at Oak Ridge, TN and contained sessions on the following topics: Fundamentals of Analytical Mass Spectrometry (MS), MS in the National Laboratories, Lasers and Fourier Transform Methods, Future of MS, New Ionization and LC/MS Methods, and an extra session. (WET)

  5. Analytical mass spectrometry. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-31

    This 43rd Annual Summer Symposium on Analytical Chemistry was held July 24--27, 1990 at Oak Ridge, TN and contained sessions on the following topics: Fundamentals of Analytical Mass Spectrometry (MS), MS in the National Laboratories, Lasers and Fourier Transform Methods, Future of MS, New Ionization and LC/MS Methods, and an extra session. (WET)

  6. Direct neutrino mass measurements

    Energy Technology Data Exchange (ETDEWEB)

    Weinheimer, Christian, E-mail: weinheimer@uni-muenster.de [Westfaelische Wilhelms-Universitaet, Institut fuer Kernphysik (Germany)

    2013-03-15

    Direct neutrino mass experiments are complementary to searches for neutrinoless double {beta}-decay and to analyses of cosmological data. The previous tritium beta decay experiments at Mainz and at Troitsk have achieved upper limits on the neutrino mass of about 2 eV/c{sup 2} . The KATRIN experiment under construction will improve the neutrino mass sensitivity down to 200 meV/c{sup 2} by increasing strongly the statistics and-at the same time-reducing the systematic uncertainties. Huge improvements have been made to operate the system extremely stably and at very low background rate. The latter comprises new methods to reject secondary electrons from the walls as well as to avoid and to eject electrons stored in traps. As an alternative to tritium {beta}-decay experiments cryo-bolometers investigating the endpoint region of {sup 187}Re {beta}-decay or the electron capture of {sup 163}Ho are being developed. This article briefly reviews the current status of the direct neutrino mass measurements.

  7. Parametric Mass Reliability Study

    Science.gov (United States)

    Holt, James P.

    2014-01-01

    The International Space Station (ISS) systems are designed based upon having redundant systems with replaceable orbital replacement units (ORUs). These ORUs are designed to be swapped out fairly quickly, but some are very large, and some are made up of many components. When an ORU fails, it is replaced on orbit with a spare; the failed unit is sometimes returned to Earth to be serviced and re-launched. Such a system is not feasible for a 500+ day long-duration mission beyond low Earth orbit. The components that make up these ORUs have mixed reliabilities. Components that make up the most mass-such as computer housings, pump casings, and the silicon board of PCBs-typically are the most reliable. Meanwhile components that tend to fail the earliest-such as seals or gaskets-typically have a small mass. To better understand the problem, my project is to create a parametric model that relates both the mass of ORUs to reliability, as well as the mass of ORU subcomponents to reliability.

  8. Mass spectrometry with accelerators.

    Science.gov (United States)

    Litherland, A E; Zhao, X-L; Kieser, W E

    2011-01-01

    As one in a series of articles on Canadian contributions to mass spectrometry, this review begins with an outline of the history of accelerator mass spectrometry (AMS), noting roles played by researchers at three Canadian AMS laboratories. After a description of the unique features of AMS, three examples, (14)C, (10)Be, and (129)I are given to illustrate the methods. The capabilities of mass spectrometry have been extended by the addition of atomic isobar selection, molecular isobar attenuation, further ion acceleration, followed by ion detection and ion identification at essentially zero dark current or ion flux. This has been accomplished by exploiting the techniques and accelerators of atomic and nuclear physics. In 1939, the first principles of AMS were established using a cyclotron. In 1977 the selection of isobars in the ion source was established when it was shown that the (14)N(-) ion was very unstable, or extremely difficult to create, making a tandem electrostatic accelerator highly suitable for assisting the mass spectrometric measurement of the rare long-lived radioactive isotope (14)C in the environment. This observation, together with the large attenuation of the molecular isobars (13)CH(-) and (12)CH 2(-) during tandem acceleration and the observed very low background contamination from the ion source, was found to facilitate the mass spectrometry of (14)C to at least a level of (14)C/C ~ 6 × 10(-16), the equivalent of a radiocarbon age of 60,000 years. Tandem Accelerator Mass Spectrometry, or AMS, has now made possible the accurate radiocarbon dating of milligram-sized carbon samples by ion counting as well as dating and tracing with many other long-lived radioactive isotopes such as (10)Be, (26)Al, (36)Cl, and (129)I. The difficulty of obtaining large anion currents with low electron affinities and the difficulties of isobar separation, especially for the heavier mass ions, has prompted the use of molecular anions and the search for alternative

  9. On the Mass Distribution of Stellar-Mass Black Holes

    Directory of Open Access Journals (Sweden)

    Malkov O. Yu.

    2014-12-01

    Full Text Available The observational stellar-mass black hole mass distribution exhibits a maximum at about 8 M⊙. It can be explained via the details of the massive star evolution, supernova explosions, or consequent black hole evolution. We propose another explanation, connected with an underestimated influence of the relation between the initial stellar mass and the compact remnant mass. We show that an unimodal observational mass distribution of black holes can be produced by a power-law initial mass function and a monotonic “remnant mass versus initial mass” relation.

  10. Mass spectrometry in clinical chemistry

    International Nuclear Information System (INIS)

    Pettersen, J.E.

    1977-01-01

    A brief description is given of the functional elements of a mass spectrometer and of some currently employed mass spectrometric techniques, such as combined gas chromatography-mass spectrometry, mass chromatography, and selected ion monitoring. Various areas of application of mass spectrometry in clinical chemistry are discussed, such as inborn errors of metabolism and other metabolic disorders, intoxications, quantitative determinations of drugs, hormones, gases, and trace elements, and the use of isotope dilution mass spectrometry as a definitive method for the establishment of true values for concentrations of various compounds in reference sera. It is concluded that mass spectrometry is of great value in clinical chemistry. (Auth.)

  11. The W Boson Mass Measurement

    CERN Document Server

    Kotwal, Ashutosh V

    2016-01-01

    The measurement of the W boson mass has been growing in importance as its precision has improved, along with the precision of other electroweak observables and the top quark mass. Over the last decade, the measurement of the W boson mass has been led at hadron colliders. Combined with the precise measurement of the top quark mass at hadron colliders, the W boson mass helped to pin down the mass of the Standard Model Higgs boson through its induced radiative correction on the W boson mass. With the discovery of the Higgs boson and the measurement of its mass, the electroweak sector of the Standard Model is over-constrained. Increasing the precision of the W boson mass probes new physics at the TeV-scale. We summarize an extensive Tevatron (1984–2011) program to measure the W boson mass at the CDF and Dø experiments. We highlight the recent Tevatron measurements and prospects for the final Tevatron measurements.

  12. Minimalistic Neutrino Mass Model

    CERN Document Server

    De Gouvêa, A; Gouvea, Andre de

    2001-01-01

    We consider the simplest model which solves the solar and atmospheric neutrino puzzles, in the sense that it contains the smallest amount of beyond the Standard Model ingredients. The solar neutrino data is accounted for by Planck-mass effects while the atmospheric neutrino anomaly is due to the existence of a single right-handed neutrino at an intermediate mass scale between 10^9 GeV and 10^14 GeV. Even though the neutrino mixing angles are not exactly predicted, they can be naturally large, which agrees well with the current experimental situation. Furthermore, the amount of lepton asymmetry produced in the early universe by the decay of the right-handed neutrino is very predictive and may be enough to explain the current baryon-to-photon ratio if the right-handed neutrinos are produced out of thermal equilibrium. One definitive test for the model is the search for anomalous seasonal effects at Borexino.

  13. Neutrino mass: Recent results

    International Nuclear Information System (INIS)

    Robertson, R.G.H.

    1989-01-01

    Some recent developments in the experimental search for neutrino mass are discussed. Simpson and Hime report finding new evidence for a 17-keV neutrino in the β decay of 3 H and 35 S. New data from Los Alamos on the electron neutrino mass as measured in tritium beta decay give an upper limit of 13.5 eV at the 95% confidence level. This result is not consistent with the long-standing ITEP result of 26(5) eV within a ''model-independent'' range of 17 to 40 eV. It now appears that the electron neutrino is not sufficiently massive to close the universe by itself. 38 refs., 1 figs., 2 tabs

  14. Coronal Mass Ejections

    CERN Document Server

    Kunow, H; Linker, J. A; Schwenn, R; Steiger, R

    2006-01-01

    It is well known that the Sun gravitationally controls the orbits of planets and minor bodies. Much less known, however, is the domain of plasma fields and charged particles in which the Sun governs a heliosphere out to a distance of about 15 billion kilometers. What forces activates the Sun to maintain this power? Coronal Mass Ejections (CMEs) and their descendants are the troops serving the Sun during high solar activity periods. This volume offers a comprehensive and integrated overview of our present knowledge and understanding of Coronal Mass Ejections (CMEs) and their descendants, Interplanetary CMEs (ICMEs). It results from a series of workshops held between 2000 and 2004. An international team of about sixty experimenters involved e.g. in the SOHO, ULYSSES, VOYAGER, PIONEER, HELIOS, WIND, IMP, and ACE missions, ground observers, and theoreticians worked jointly on interpreting the observations and developing new models for CME initiations, development, and interplanetary propagation. The book provides...

  15. Large mass storage facility

    Energy Technology Data Exchange (ETDEWEB)

    Peskin, Arnold M.

    1978-08-01

    This is the final report of a study group organized to investigate questions surrounding the acquisition of a large mass storage facility. The programatic justification for such a system at Brookhaven is reviewed. Several candidate commercial products are identified and discussed. A draft of a procurement specification is developed. Some thoughts on possible new directions for computing at Brookhaven are also offered, although this topic was addressed outside of the context of the group's deliberations. 2 figures, 3 tables.

  16. Neutrino Masses and Oscillations

    CERN Multimedia

    CERN. Geneva. Audiovisual Unit; Treille, Daniel

    2002-01-01

    This course will not cover its subject in the customary way. The emphasis will be on the simple theoretical concepts (helicity, handedness, chirality, Majorana masses) which are obscure in most of the literature, and on the quantum mechanics of oscillations, that ALL books get wrong. Which, hopefully, will not deter me from discussing some of the most interesting results from the labs and from the cosmos.

  17. Hydrogen Exchange Mass Spectrometry

    Science.gov (United States)

    Mayne, Leland

    2018-01-01

    Hydrogen exchange (HX) methods can reveal much about the structure, energetics, and dynamics of proteins. The addition of mass spectrometry (MS) to an earlier fragmentation-separation HX analysis now extends HX studies to larger proteins at high structural resolution and can provide information not available before. This chapter discusses experimental aspects of HX labeling, especially with respect to the use of MS and the analysis of MS data. PMID:26791986

  18. Gravitational field mass

    International Nuclear Information System (INIS)

    Penrose, R.

    1986-01-01

    The author's definition for the mass-momentum/angular momentum surrounded by a spacelike 2-surface with S/sup 2/ topology is presented. This definition is motivated by some ideas from twistor theory in relation to linearized gravitational theory. The status of this definition is examined in relation to many examples which have been worked out. The reason for introducing a slight modification of the original definition is also presented

  19. Neutrino masses and mixings

    International Nuclear Information System (INIS)

    Wolfenstein, L.

    1991-01-01

    Theoretical prejudices, cosmology, and neutrino oscillation experiments all suggest neutrino mass are far below present direct experimental limits. Four interesting scenarios and their implications are discussed: (1) a 17 keV ν τ , (2) a 30 ev ν τ making up the dark matter, (3) a 10 -3 ev ν μ to solve the solar neutrino problem, and (4) a three-neutrino MSW solution

  20. Handbook of mass measurement

    CERN Document Server

    Jones, Frank E

    2002-01-01

    "How much does it weigh?" seems a simple question. To scientists and engineers, however, the answer is far from simple, and determining the answer demands consideration of an almost overwhelming number of factors.With an intriguing blend of history, fundamentals, and technical details, the Handbook of Mass Measurement sets forth the details of achieving the highest precision in mass measurements. It covers the whole field, from the development, calibration, and maintenance of mass standards to detailed accounts of weighing designs, balances, and uncertainty. It addresses the entire measurement process and provides in-depth examinations of the various factors that introduce error.Much of the material is the authors'' own work and some of it is published here for the first time. Jones and Schoonover are both highly regarded veterans of the U.S. National Institute of Standards and Technology. With this handbook, they have provided a service and resource vital to anyone involved not only in the determination of m...

  1. Masses of noble gases

    CERN Document Server

    Marx, G H; Herfurth, F; Stora, T; Blaum, K; Beck, D; Audi, G; Rosenbusch, M

    The so-called magic numbers, cornerstones of the quantum nuclear ensemble, are now known to lose their supernatural powers far from the protected valley of stability. To complement the well-established (but not yet well-understood) case of N = 20, we propose to examine the erstwhile N = 28 shell closure via a measurement of the important (but unknown) mass of the nuclide $^{48}$Ar. The quenching of a shell closure, a mechanism as mysterious as the reason for magic numbers themselves, also has important consequences in nucleosynthesis. While $^{48}$Ar is not part of the region concerned by the canonical rapid neutro-capture r-process, the question of shell strength is of great importance for heavier nuclides. The location of the r-process path would benefit from extending the succesful ISOTRAP krypton mass measurements beyond the N = 58 sub-shell to $^{96-98}$Kr. Modeling the complementary rapid proton-capture rp- process, putative source of some proton-rich species, requires the mass of $^{70}$Kr, near the e...

  2. Slope of the mass function of low-mass stars

    International Nuclear Information System (INIS)

    Malkov, O.Yu.

    1987-01-01

    It is shown that the modern method of obtaining the initial mass function contains a number of a uncertainties that can have a significant effect on the slope of the function in the low-mass section (m < m**). The influence of changes of the mass-luminosity relation, the scale of bolometric corrections, and the luminosity function on the form of the mass function is considered. The effect of photometrically unresolved binaries is also discussed. Some quantitative estimates are made, and it is shown that the slope of the initial mass function in the low-mass section can vary in wide ranges

  3. Evolutionary effects of mass loss in low-mass stars

    International Nuclear Information System (INIS)

    Renzini, A.

    1981-01-01

    The effects of mass loss on the evolution of low-mass stars (actual mass smaller than 1.4 solar masses) are reviewed. The case of globular cluster stars is discussed in some detail, and it is shown that evolutionary theory sets quite precise limits to the mass-loss rate in population II red giants. The effects of mass loss on the final evolutionary stages of stars producing white dwarfs is also discussed. In particular, the interaction of the wind from the hot central star with the surrounding planetary nebula is considered. Finally, the problem of the origin of hydrogen-deficient stars is briefly discussed. (Auth.)

  4. Charm mass corrections to the bottomonium mass spectrum

    International Nuclear Information System (INIS)

    Ebert, D.; Faustov, R. N.; Galkin, V. O.

    2002-01-01

    The one-loop corrections to the bottomonium mass spectrum due to the finite charm mass are evaluated in the framework of the relativistic quark model. The obtained corrections are compared with the results of perturbative QCD

  5. Static-light meson masses from twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Jansen, Karl; Michael, Chris; Shindler, Andrea; Wagner, Marc

    2008-08-01

    We compute the static-light meson spectrum using two-flavor Wilson twisted mass lattice QCD. We have considered five different values for the light quark mass corresponding to 300 MeV PS S mesons. (orig.)

  6. Body mass in comparative primatology.

    Science.gov (United States)

    Smith, R J; Jungers, W L

    1997-06-01

    Data are presented on adult body mass for 230 of 249 primate species, based on a review of the literature and previously unpublished data. The issues involved in collecting data on adult body mass are discussed, including the definition of adults, the effects of habitat and pregnancy, the strategy for pooling data on single species from multiple studies, and use of an appropriate number of significant figures. An analysis of variability in body mass indicates that the coefficient of variation for body mass increases with increasing species mean mass. Evaluation of several previous body mass reviews reveals a number of shortcomings with data that have been used often in comparative studies.

  7. Twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Shindler, A.

    2007-07-01

    I review the theoretical foundations, properties as well as the simulation results obtained so far of a variant of the Wilson lattice QCD formulation: Wilson twisted mass lattice QCD. Emphasis is put on the discretization errors and on the effects of these discretization errors on the phase structure for Wilson-like fermions in the chiral limit. The possibility to use in lattice simulations different lattice actions for sea and valence quarks to ease the renormalization patterns of phenomenologically relevant local operators, is also discussed. (orig.)

  8. Gas Chromatic Mass Spectrometer

    Science.gov (United States)

    Wey, Chowen

    1995-01-01

    Gas chromatograph/mass spectrometer (GC/MS) used to measure and identify combustion species present in trace concentration. Advanced extractive diagnostic method measures to parts per billion (PPB), as well as differentiates between different types of hydrocarbons. Applicable for petrochemical, waste incinerator, diesel transporation, and electric utility companies in accurately monitoring types of hydrocarbon emissions generated by fuel combustion, in order to meet stricter environmental requirements. Other potential applications include manufacturing processes requiring precise detection of toxic gaseous chemicals, biomedical applications requiring precise identification of accumulative gaseous species, and gas utility operations requiring high-sensitivity leak detection.

  9. Fermion masses from superstrings

    International Nuclear Information System (INIS)

    Tanaka, K.

    1986-01-01

    It is assumed that the E 8 gauge group of the E 8 x E 8 heterotic superstring can be broken into SO(10) x SU(4). The mass relations among fermions m/sub u//m/sub d/ = m/sub c//m/sub s/ = m/sub t//m/sub b/ and m/sub ν e//m/sub e/ = m/sub ν mu//m/sub μ/ = m/sub ν tau//m/sub tau/ are discussed. 18 refs

  10. Triple mode Cepheid masses

    International Nuclear Information System (INIS)

    King, D.S.; Cox, A.N.; Hodson, S.W.

    1978-01-01

    Cepheid wind enrichment from the surface and the instability mixing below the convection zones compete to give much deeper large Y homogeneous and transition layers than previously thought. The theoretical model data and derived masses are presented. It is shown that if the helium enrichment goes to 250,000 K (l-q = 2 x 10 -4 ) with a transition zone to 300,000 K (1-q = 5 x 10 -4 ) for AC And, its periods can be explained. For TU Cas a very unlikely model is required to give the three periods reported previously. 28 references

  11. Photon mass and electrogenesis

    International Nuclear Information System (INIS)

    Dolgov, Alexander; Pelliccia, Diego N.

    2007-01-01

    We show that if the photon possesses a tiny but non-vanishing mass, the universe cannot be electrically neutral. A cosmological electric asymmetry could be generated either at an early stage by the different evaporation rates of the primordial black holes with respect to positively and negatively charged particles or by a predominant capture of protons in comparison to electrons by the heavy galactic black holes in the contemporary universe. An impact of this phenomenon on the generation of large scale magnetic fields and on the acceleration of the universe is considered

  12. Higgs for the masses

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1986-03-15

    The unified theory of electromagnetism and the weak nuclear force, crowned with the discovery at CERN in 1983 of the W and Z bosons which carry the weak nuclear force, is one of the great triumphs of modern physics. But the picture is not yet complete. An essential but still elusive ingredient is the so-called 'Higgs boson' (after Edinburgh theorist Peter Higgs), responsible for the vital symmetry breaking in the theory. This gives the carriers of the weak force mass, while the photon, the carrier of electromagnetism, is massless.

  13. Mass extinctions of Earth

    International Nuclear Information System (INIS)

    Fernandez, B.; Fernandez, P.; Pereira, B.

    2015-01-01

    Throughout the history of our planet, there have been global phenomena which have led to the disappearance of a large number of species: It is what is known as mass or massive extinctions. This article will make a tour of these large events, from the most remote antiquity to the present day. Today we find ourselves immersed in a process unprecedented since we are eyewitnesses and, more important still, an active part in the decision-making process to try to mitigate their effects. (Author)

  14. Twisted mass lattice QCD

    Energy Technology Data Exchange (ETDEWEB)

    Shindler, A. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

    2007-07-15

    I review the theoretical foundations, properties as well as the simulation results obtained so far of a variant of the Wilson lattice QCD formulation: Wilson twisted mass lattice QCD. Emphasis is put on the discretization errors and on the effects of these discretization errors on the phase structure for Wilson-like fermions in the chiral limit. The possibility to use in lattice simulations different lattice actions for sea and valence quarks to ease the renormalization patterns of phenomenologically relevant local operators, is also discussed. (orig.)

  15. ON THE MASS DISTRIBUTION AND BIRTH MASSES OF NEUTRON STARS

    International Nuclear Information System (INIS)

    Özel, Feryal; Psaltis, Dimitrios; Santos Villarreal, Antonio; Narayan, Ramesh

    2012-01-01

    We investigate the distribution of neutron star masses in different populations of binaries, employing Bayesian statistical techniques. In particular, we explore the differences in neutron star masses between sources that have experienced distinct evolutionary paths and accretion episodes. We find that the distribution of neutron star masses in non-recycled eclipsing high-mass binaries as well as of slow pulsars, which are all believed to be near their birth masses, has a mean of 1.28 M ☉ and a dispersion of 0.24 M ☉ . These values are consistent with expectations for neutron star formation in core-collapse supernovae. On the other hand, double neutron stars, which are also believed to be near their birth masses, have a much narrower mass distribution, peaking at 1.33 M ☉ , but with a dispersion of only 0.05 M ☉ . Such a small dispersion cannot easily be understood and perhaps points to a particular and rare formation channel. The mass distribution of neutron stars that have been recycled has a mean of 1.48 M ☉ and a dispersion of 0.2 M ☉ , consistent with the expectation that they have experienced extended mass accretion episodes. The fact that only a very small fraction of recycled neutron stars in the inferred distribution have masses that exceed ∼2 M ☉ suggests that only a few of these neutron stars cross the mass threshold to form low-mass black holes.

  16. The Cepheid mass discrepancy and pulsation-driven mass loss

    NARCIS (Netherlands)

    Neilson, H.R.; Cantiello, M.; Langer, N.

    2011-01-01

    Context. A longstanding challenge for understanding classical Cepheids is the Cepheid mass discrepancy, where theoretical mass estimates using stellar evolution and stellar pulsation calculations have been found to differ by approximately 10−20%. Aims. We study the role of pulsation-driven mass loss

  17. Efficient mass calibration of magnetic sector mass spectrometers

    International Nuclear Information System (INIS)

    Roddick, J.C.

    1996-01-01

    Magnetic sector mass spectrometers used for automatic acquisition of precise isotopic data are usually controlled with Hall probes and software that uses polynomial equations to define and calibrate the mass-field relations required for mass focusing. This procedure requires a number of reference masses and careful tuning to define and maintain an accurate mass calibration. A simplified equation is presented and applied to several different magnetically controlled mass spectrometers. The equation accounts for nonlinearity in typical Hall probe controlled mass-field relations, reduces calibration to a linear fitting procedure, and is sufficiently accurate to permit calibration over a mass range of 2 to 200 amu with only two defining masses. Procedures developed can quickly correct for normal drift in calibrations and compensate for drift during isotopic analysis over a limited mass range such as a single element. The equation is: Field A·Mass 1/2 + B·(Mass) p where A, B, and p are constants. The power value p has a characteristic value for a Hall probe/controller and is insensitive to changing conditions, thus reducing calibration to a linear regression to determine optimum A and B. (author). 1 ref., 1 tab., 6 figs

  18. Efficient mass calibration of magnetic sector mass spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Roddick, J C

    1997-12-31

    Magnetic sector mass spectrometers used for automatic acquisition of precise isotopic data are usually controlled with Hall probes and software that uses polynomial equations to define and calibrate the mass-field relations required for mass focusing. This procedure requires a number of reference masses and careful tuning to define and maintain an accurate mass calibration. A simplified equation is presented and applied to several different magnetically controlled mass spectrometers. The equation accounts for nonlinearity in typical Hall probe controlled mass-field relations, reduces calibration to a linear fitting procedure, and is sufficiently accurate to permit calibration over a mass range of 2 to 200 amu with only two defining masses. Procedures developed can quickly correct for normal drift in calibrations and compensate for drift during isotopic analysis over a limited mass range such as a single element. The equation is: Field A{center_dot}Mass{sup 1/2} + B{center_dot}(Mass){sup p} where A, B, and p are constants. The power value p has a characteristic value for a Hall probe/controller and is insensitive to changing conditions, thus reducing calibration to a linear regression to determine optimum A and B. (author). 1 ref., 1 tab., 6 figs.

  19. Twisted mass lattice QCD with non-degenerate quark masses

    International Nuclear Information System (INIS)

    Muenster, Gernot; Sudmann, Tobias

    2006-01-01

    Quantum Chromodynamics on a lattice with Wilson fermions and a chirally twisted mass term is considered in the framework of chiral perturbation theory. For two and three numbers of quark flavours, respectively, with non-degenerate quark masses the pseudoscalar meson masses and decay constants are calculated in next-to-leading order including lattice effects quadratic in the lattice spacing a

  20. Respiratory mass spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Mostert, J.W. (Pretoria Univ. (South Africa). Dept. of Anesthesiology)

    1983-06-01

    The high degree of technical perfection of the respiratory mass spectrometer has rendered the instrument feasible for routine monitoring of anesthetized patients. It is proposed that the difference between inspired and expired oxygen tension in mm Hg be equated with whole body oxygen consumption in ml/min/M/sup 2/ body-surface area at STPD, by the expedient of multiplying tension-differences by a factor of 2. Years of experience have confirmed the value of promptly recognizing sudden drops in this l/E tension difference below 50 mm Hg indicative of metabolic injury from hypovolemia or respiratory depression. Rises in l/E tension-differences were associated with shivering as well as voluntary muscle activity. Tension differences of less than 25 mm Hg (equated with a whole-body O/sub 2/ consumption of less than 50 ml O/sub 2//min/M/sup 2/) occurred in a patient in the sitting position for posterior fossa exploration without acidosis, hypoxia or hypotension for several hours prior to irreversible cardiac arrest. The value of clinical monitoring by mass spectrometry is especially impressive in open-heart surgery.

  1. The respiratory mass spectrometer

    International Nuclear Information System (INIS)

    Mostert, J.W.

    1983-01-01

    The high degree of technical perfection of the respiratory mass spectrometer has rendered the instrument feasible for routine monitoring of anesthetized patients. It is proposed that the difference between inspired and expired oxygen tension in mm Hg be equated with whole body oxygen consumption in ml/min/M 2 body-surface area at STPD, by the expedient of multiplying tension-differences by a factor of 2. Years of experience have confirmed the value of promptly recognizing sudden drops in this l/E tension difference below 50 mm Hg indicative of metabolic injury from hypovolemia or respiratory depression. Rises in l/E tension-differences were associated with shivering as well as voluntary muscle activity. Tension differences of less than 25 mm Hg (equated with a whole-body O 2 consumption of less than 50 ml O 2 /min/M 2 ) occurred in a patient in the sitting position for posterior fossa exploration without acidosis, hypoxia or hypotension for several hours prior to irreversible cardiac arrest. The value of clinical monitoring by mass spectrometry is especially impressive in open-heart surgery

  2. Added masses of ship structures

    CERN Document Server

    Korotkin, Alexandr I

    2008-01-01

    This essentially self-contained reference book contains data on added masses of ships and various ship and marine engineering structures. Theoretical and experimental methods for determining added masses of these objects are described.

  3. Gas chromatography: mass selective detector

    International Nuclear Information System (INIS)

    Lapinskas, R.

    1988-01-01

    The mechanism of mass spectrometry technique directed for detecting molecular structures is described, with some considerations about its operational features. This mass spectrometer is used as a gas chromatography detector. (author)

  4. Mass of the spirals galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Maupome, L; Pismis, P; Aguilar, L [Universidad Nacional Autonoma de Mexico, Mexico City. Inst. de Astronomia

    1981-01-01

    In an earlier paper we have found that the total mass of galaxies-especially of the spirals-based on values published until 1975, decreased as the Hubble type varied from Sa through Sc and Irregulars. It was also pointed out that masses determined from the hydrogen 21-cm line were higher than the optically determined masses. To investigate the cause of these tendencies we have estimated the masses using an analytic rotation curve of Brandt adjusted to the optical observations in order to include all the mass of a galaxy up to the last observed point. Although the masses computed in this manner were found to be larger, as expected, the decrease of mass with Hubble type found earlier is confirmed. However, there is a discrepancy in the earlier types (Sa, Sab) in that their radio-masses are smaller than the optically determined ones. At present, the cause of this is not clear.

  5. Calculate Your Body Mass Index

    Science.gov (United States)

    ... Can! ) Health Professional Resources Calculate Your Body Mass Index Body mass index (BMI) is a measure of body fat based ... Health Information Email Alerts Jobs and Careers Site Index About NHLBI National Institute of Health Department of ...

  6. THE MASS DISTRIBUTION OF STELLAR-MASS BLACK HOLES

    International Nuclear Information System (INIS)

    Farr, Will M.; Sravan, Niharika; Kalogera, Vicky; Cantrell, Andrew; Kreidberg, Laura; Bailyn, Charles D.; Mandel, Ilya

    2011-01-01

    We perform a Bayesian analysis of the mass distribution of stellar-mass black holes using the observed masses of 15 low-mass X-ray binary systems undergoing Roche lobe overflow and 5 high-mass, wind-fed X-ray binary systems. Using Markov Chain Monte Carlo calculations, we model the mass distribution both parametrically—as a power law, exponential, Gaussian, combination of two Gaussians, or log-normal distribution—and non-parametrically—as histograms with varying numbers of bins. We provide confidence bounds on the shape of the mass distribution in the context of each model and compare the models with each other by calculating their relative Bayesian evidence as supported by the measurements, taking into account the number of degrees of freedom of each model. The mass distribution of the low-mass systems is best fit by a power law, while the distribution of the combined sample is best fit by the exponential model. This difference indicates that the low-mass subsample is not consistent with being drawn from the distribution of the combined population. We examine the existence of a 'gap' between the most massive neutron stars and the least massive black holes by considering the value, M 1% , of the 1% quantile from each black hole mass distribution as the lower bound of black hole masses. Our analysis generates posterior distributions for M 1% ; the best model (the power law) fitted to the low-mass systems has a distribution of lower bounds with M 1% >4.3 M sun with 90% confidence, while the best model (the exponential) fitted to all 20 systems has M 1% >4.5 M sun with 90% confidence. We conclude that our sample of black hole masses provides strong evidence of a gap between the maximum neutron star mass and the lower bound on black hole masses. Our results on the low-mass sample are in qualitative agreement with those of Ozel et al., although our broad model selection analysis more reliably reveals the best-fit quantitative description of the underlying mass

  7. Localizability and the planck mass

    International Nuclear Information System (INIS)

    Ne'eman, Y.; Univ. of Texas, Austin, TX

    1993-06-01

    The author combines the assumption of environmental decoherence, as the mechanism generating the classical (i.e. no quantum interferences) nature of spacetime, with the limit on its other classical feature, point-like continuity, namely Planck length. As a result, quantum extended objects with masses larger than Planck mass have to derive their quantum behavior from long-range correlations; objects with masses smaller than Planck mass cannot display classical behavior

  8. Mass Spectrometry Instrumentation in Proteomics

    DEFF Research Database (Denmark)

    Sprenger, Richard Remko; Roepstorff, Peter

    2012-01-01

    Mass spectrometry has evolved into a crucial technology for the field of proteomics, enabling the comprehensive study of proteins in biological systems. Innovative developments have yielded flexible and versatile mass spectrometric tools, including quadrupole time-of-flight, linear ion trap......, Orbitrap and ion mobility instruments. Together they offer various and complementary capabilities in terms of ionization, sensitivity, speed, resolution, mass accuracy, dynamic range and methods of fragmentation. Mass spectrometers can acquire qualitative and quantitative information on a large scale...

  9. Video Games as Mass Art

    OpenAIRE

    Grant Tavinor

    2011-01-01

    Videogames are one of the most significant developments in the mass arts of recent times. In commercial terms, they are now among the most prominent of the mass arts worldwide. This commercial and cultural success does not exhaust the interest in videogames as a mass art phenomenon because games such as Grand Theft Auto IV and Fallout 3 are structurally radically different from previous forms of mass art. In particular, the ontology of videogames, the nature and identity of their works, and...

  10. Diagonalization of the mass matrices

    International Nuclear Information System (INIS)

    Rhee, S.S.

    1984-01-01

    It is possible to make 20 types of 3x3 mass matrices which are hermitian. We have obtained unitary matrices which could diagonalize each mass matrix. Since the three elements of mass matrix can be expressed in terms of the three eigenvalues, msub(i), we can also express the unitary matrix in terms of msub(i). (Author)

  11. Mass distributions in disk galaxies

    NARCIS (Netherlands)

    Martinsson, Thomas; Verheijen, Marc; Bershady, Matthew; Westfall, Kyle; Andersen, David; Swaters, Rob

    We present results on luminous and dark matter mass distributions in disk galaxies from the DiskMass Survey. As expected for normal disk galaxies, stars dominate the baryonic mass budget in the inner region of the disk; however, at about four optical scale lengths (hR ) the atomic gas starts to

  12. Neutrino mass sum-rule

    Science.gov (United States)

    Damanik, Asan

    2018-03-01

    Neutrino mass sum-rele is a very important research subject from theoretical side because neutrino oscillation experiment only gave us two squared-mass differences and three mixing angles. We review neutrino mass sum-rule in literature that have been reported by many authors and discuss its phenomenological implications.

  13. Mass measurement of radioactive isotopes

    CERN Document Server

    Kluge, H J; Scheidenberger, C

    2004-01-01

    The highest precision in mass measurements on short-lived radionuclides is obtained using trapping and cooling techniques. Here, the experimental storage ring (ESR) at GSI/Darmstadt and the tandem Penning trap mass spectrometer ISOLTRAP at ISOLDE/CERN play an important role. Status and recent results on mass measurements of radioactive nuclides with ESR and ISOLTRAP are summarized.

  14. Instrumentation for mass spectrometry: 1997

    Energy Technology Data Exchange (ETDEWEB)

    McLuckey, S.A.

    1997-08-01

    All mass spectrometry experiments involve the manipulation of material, an interface with the mass spectrometer, ionization, ion manipulation/analysis, detection and data collection/reduction. Each of these elements involve instrumentation. The wide range of species now amenable to mass spectrometry and the diverse areas of physical science in which it plays a role have led to a seemingly unlimited array of instrumental combinations. However, only a limited number of mass analyzers, and their combinations, dominate. The dominant analyzers include time-of-flight, Fourier transform ion cyclotron resonance, the Paul trap, the mass filter, and the sector mass spectrometer. Why there are so few (or so many, depending upon one`s point of view) can be understood upon consideration of a set of mass analyzer figures of merit. These include mass resolution, mass accuracy, mass range, dynamic range, abundance sensitivity, precision, efficiency, speed, MS{sup n} capability, compatibility with the ionizer, cost, and size. The most appropriate form of mass spectrometry is determined by the priorities of the particular measurement placed on the various mass analyzer characteristics and the relative strengths of the analyzers in meeting the requirements. Each of the analyzer types has a unique set of figures of merit that makes it optimally suited for particular applications. This paper discusses these figures of merit, provides data illustrating recent developments for each analyzer type, and gives the figures of merit of each type of analyzer as they stand in 1997. 101 refs., 24 figs.

  15. Mass Transport within Soils

    Energy Technology Data Exchange (ETDEWEB)

    McKone, Thomas E.

    2009-03-01

    Contaminants in soil can impact human health and the environment through a complex web of interactions. Soils exist where the atmosphere, hydrosphere, geosphere, and biosphere converge. Soil is the thin outer zone of the earth's crust that supports rooted plants and is the product of climate and living organisms acting on rock. A true soil is a mixture of air, water, mineral, and organic components. The relative proportions of these components determine the value of the soil for agricultural and for other human uses. These proportions also determine, to a large extent, how a substance added to soil is transported and/or transformed within the soil (Spositio, 2004). In mass-balance models, soil compartments play a major role, functioning both as reservoirs and as the principal media for transport among air, vegetation, surface water, deeper soil, and ground water (Mackay, 2001). Quantifying the mass transport of chemicals within soil and between soil and atmosphere is important for understanding the role soil plays in controlling fate, transport, and exposure to multimedia pollutants. Soils are characteristically heterogeneous. A trench dug into soil typically reveals several horizontal layers having different colors and textures. As illustrated in Figure 1, these multiple layers are often divided into three major horizons: (1) the A horizon, which encompasses the root zone and contains a high concentration of organic matter; (2) the B horizon, which is unsaturated, lies below the roots of most plants, and contains a much lower organic carbon content; and (3) the C horizon, which is the unsaturated zone of weathered parent rock consisting of bedrock, alluvial material, glacial material, and/or soil of an earlier geological period. Below these three horizons lies the saturated zone - a zone that encompasses the area below ground surface in which all interconnected openings within the geologic media are completely filled with water. Similarly to the unsaturated

  16. Heat and mass transfer

    CERN Document Server

    Karwa, Rajendra

    2017-01-01

    This textbook presents the classical treatment of the problems of heat transfer in an exhaustive manner with due emphasis on understanding of the physics of the problems. This emphasis is especially visible in the chapters on convective heat transfer. Emphasis is laid on the solution of steady and unsteady two-dimensional heat conduction problems. Another special feature of the book is a chapter on introduction to design of heat exchangers and their illustrative design problems. A simple and understandable treatment of gaseous radiation has been presented. A special chapter on flat plate solar air heater has been incorporated that covers thermo-hydraulic modeling and simulation. The chapter on mass transfer has been written looking specifically at the needs of the students of mechanical engineering. The book includes a large number and variety of solved problems with supporting line diagrams. The author has avoided duplicating similar problems, while incorporating more application-based examples. All the end-...

  17. Mass transport by groundwater

    International Nuclear Information System (INIS)

    Ledoux, E.; Goblet, P.; Jamet, Ph.; De Marsily, G.; Des Orres, P.E.; Lewi, J.

    1991-01-01

    The first analyses of the safety of radioactive waste disposal published in 1970s were mostly of a generic type using the models of radionuclide migration in the geosphere. These simply constructed models gave way to more sophisticated techniques in order to represent better the complexity and diversity of geological media. In this article, it is attempted to review the various concepts used to quantify radionuclide migration and the evolution of their incorporation into the models. First, it was examined how the type of discontinuity occurring in geological media affects the choice of a representative model. The principle of transport in the subsurface was reviewed, and the effect that coupled processes exert to groundwater flow and mass migration was discussed. The processes that act directly to cause groundwater flow were distinguished. The method of validating such models by comparing the results with the geochemical systems in nature was explained. (K.I.)

  18. Neutrino masses and mixing

    International Nuclear Information System (INIS)

    Fogli, G.

    1998-01-01

    The paper presents an analysis of the solar neutrino problem in terms of both Mikheyev-Smirnov-Wolfenstein (MSW) and vacuum neutrino oscillations, with the inclusion of the data collected by the SuperKamiokande experiment during 306.3 days of operation. In particular, the observed energy spectrum of the recoil electrons from 8 B neutrino scattering is discussed in detail and used to constrain the mass-mixing parameter space. Going to the atmospheric neutrino anomaly, the paper performs both a two- and three-flavor analysis of the most recent SuperKamiokande atmospheric neutrino data. The variations of the zenith distributions of ν events in the presence of flavor oscillations are investigated. It is seen that fits to the SK data, with and without the addition of the CHOOZ constrains, strongly limit the parameter space. Detailed bounds in triangle graphs are reported

  19. The Mass Media

    DEFF Research Database (Denmark)

    Valentini, Chiara; Laursen, Bo

    2012-01-01

    spaces. We postulate that citizens’ levels of awareness and knowledge of EU matters depend on the EU institutions’ ability to reach European citizens directly or indirectly through a wide range of channels, including the mass media. Citizens’ participation in political debates, however, requires more......(s). The EU institutions also need to communicate frames of interpretation around political issues. In this chapter we analyse the EU institutions’ external communication and specifically their media relations efforts, and suggest improvements in view of remedying some of the legitimacy problems that the EU......This chapter deals with the EU institutions’ external communication and how it relates to the European public sphere(s). We argue that one of the preconditions for establishing a well-functioning European public sphere is that the EU institutions’ decision-making and political debates around...

  20. The masses of cataclysmic variables

    International Nuclear Information System (INIS)

    Robinson, E.L.

    1976-01-01

    Masses are derived for the individual components of six cataclysmic variables. There is a considerable spread in the masses of the white dwarf components, which range from 0.73 M/sub sun/ in EM Cyg to 1.26 M/sub sun/ in Z Cam. All of the white dwarfs have masses greater than 0.70 M/sub sun/, but there is no evidence that there is any preferred mass. It is found that the morphology of the eruptions (i.e., nova versus dwarf nova) is independent of the mass of both the white dwarf and the late-type star

  1. Imaging of fetal chest masses

    Energy Technology Data Exchange (ETDEWEB)

    Barth, Richard A. [Lucile Packard Children' s Hospital, Stanford University School of Medicine, Department of Radiology, Stanford, CA (United States)

    2012-01-15

    Prenatal imaging with high-resolution US and rapid acquisition MRI plays a key role in the accurate diagnosis of congenital chest masses. Imaging has enhanced our understanding of the natural history of fetal lung masses, allowing for accurate prediction of outcome, parental counseling, and planning of pregnancy and newborn management. This paper will focus on congenital bronchopulmonary malformations, which account for the vast majority of primary lung masses in the fetus. In addition, anomalies that mimic masses and less common causes of lung masses will be discussed. (orig.)

  2. Sustainability Evaluation of Mass Customization

    DEFF Research Database (Denmark)

    Brunø, Thomas Ditlev; Nielsen, Kjeld; Taps, Stig B.

    2013-01-01

    This paper addresses the issue whether the concepts mass customization and sustainability are fundamentally compatible by asking the question: can a mass customized product be sustainable? Some factors indicate that mass customized products are less sustainable than standardized products; however...... other factors suggest the opposite. This paper explores these factors during three life cycle phases for a product: Production, Use and End of Life. It is concluded that there is not an unambiguous causal relationship between mass customization and sustainability; however several factors unique to mass...... customized products are essential to consider during product development....

  3. Unification and fermion mass structure

    International Nuclear Information System (INIS)

    Ross, Graham G.; Serna, Mario

    2008-01-01

    Grand Unified Theories predict relationships between the GUT-scale quark and lepton masses. Using new data in the context of the MSSM, we update the values and uncertainties of the masses and mixing angles for the three generations at the GUT scale. We also update fits to hierarchical patterns in the GUT-scale Yukawa matrices. The new data shows not all the classic GUT-scale mass relationships remain in quantitative agreement at small to moderate tanβ. However, at large tanβ, these discrepancies can be eliminated by finite, tanβ-enhanced, radiative, threshold corrections if the gluino mass has the opposite sign to the wino mass

  4. Positron effective mass in silicon

    International Nuclear Information System (INIS)

    Panda, B.K.; Shan, Y.Y.; Fung, S.; Beling, C.D.

    1995-01-01

    The positron effective mass in Si is obtained from the first-principles calculations along various crystallographic directions. The effect of electron-positron correlation on the band mass is examined in this work. A positron pseudopotential scheme is worked out to calculate the isotropic band mass without explicitly solving the band energy. The effective mass 1.46m obtained as a sum of band mass and the positron-plasmon interaction compares very well with 1.5m obtained from the positron mobility data

  5. Nucleon and delta masses in twisted mass chiral perturbation theory

    International Nuclear Information System (INIS)

    Walker-Loud, Andre; Wu, Jackson M.S.

    2005-01-01

    We calculate the masses of the nucleons and deltas in twisted mass heavy baryon chiral perturbation theory. We work to quadratic order in a power counting scheme in which we treat the lattice spacing, a, and the quark masses, m q , to be of the same order. We give expressions for the mass and the mass splitting of the nucleons and deltas both in and away from the isospin limit. We give an argument using the chiral Lagrangian treatment that, in the strong isospin limit, the nucleons remain degenerate and the delta multiplet breaks into two degenerate pairs to all orders in chiral perturbation theory. We show that the mass splitting between the degenerate pairs of the deltas first appears at quadratic order in the lattice spacing. We discuss the subtleties in the effective chiral theory that arise from the inclusion of isospin breaking

  6. Boundaries of mass resolution in native mass spectrometry.

    Science.gov (United States)

    Lössl, Philip; Snijder, Joost; Heck, Albert J R

    2014-06-01

    Over the last two decades, native mass spectrometry (MS) has emerged as a valuable tool to study intact proteins and noncovalent protein complexes. Studied experimental systems range from small-molecule (drug)-protein interactions, to nanomachineries such as the proteasome and ribosome, to even virus assembly. In native MS, ions attain high m/z values, requiring special mass analyzers for their detection. Depending on the particular mass analyzer used, instrumental mass resolution does often decrease at higher m/z but can still be above a couple of thousand at m/z 5000. However, the mass resolving power obtained on charge states of protein complexes in this m/z region is experimentally found to remain well below the inherent instrument resolution of the mass analyzers employed. Here, we inquire into reasons for this discrepancy and ask how native MS would benefit from higher instrumental mass resolution. To answer this question, we discuss advantages and shortcomings of mass analyzers used to study intact biomolecules and biomolecular complexes in their native state, and we review which other factors determine mass resolving power in native MS analyses. Recent examples from the literature are given to illustrate the current status and limitations.

  7. Mass: Fortran program for calculating mass-absorption coefficients

    International Nuclear Information System (INIS)

    Nielsen, Aa.; Svane Petersen, T.

    1980-01-01

    Determinations of mass-absorption coefficients in the x-ray analysis of trace elements are an important and time consuming part of the arithmetic calculation. In the course of time different metods have been used. The program MASS calculates the mass-absorption coefficients from a given major element analysis at the x-ray wavelengths normally used in trace element determinations and lists the chemical analysis and the mass-absorption coefficients. The program is coded in FORTRAN IV, and is operational on the IBM 370/165 computer, on the UNIVAC 1110 and on PDP 11/05. (author)

  8. Hierarchical quark mass matrices

    International Nuclear Information System (INIS)

    Rasin, A.

    1998-02-01

    I define a set of conditions that the most general hierarchical Yukawa mass matrices have to satisfy so that the leading rotations in the diagonalization matrix are a pair of (2,3) and (1,2) rotations. In addition to Fritzsch structures, examples of such hierarchical structures include also matrices with (1,3) elements of the same order or even much larger than the (1,2) elements. Such matrices can be obtained in the framework of a flavor theory. To leading order, the values of the angle in the (2,3) plane (s 23 ) and the angle in the (1,2) plane (s 12 ) do not depend on the order in which they are taken when diagonalizing. We find that any of the Cabbibo-Kobayashi-Maskawa matrix parametrizations that consist of at least one (1,2) and one (2,3) rotation may be suitable. In the particular case when the s 13 diagonalization angles are sufficiently small compared to the product s 12 s 23 , two special CKM parametrizations emerge: the R 12 R 23 R 12 parametrization follows with s 23 taken before the s 12 rotation, and vice versa for the R 23 R 12 R 23 parametrization. (author)

  9. Accelerator mass spectrometry.

    Science.gov (United States)

    Hellborg, Ragnar; Skog, Göran

    2008-01-01

    In this overview the technique of accelerator mass spectrometry (AMS) and its use are described. AMS is a highly sensitive method of counting atoms. It is used to detect very low concentrations of natural isotopic abundances (typically in the range between 10(-12) and 10(-16)) of both radionuclides and stable nuclides. The main advantages of AMS compared to conventional radiometric methods are the use of smaller samples (mg and even sub-mg size) and shorter measuring times (less than 1 hr). The equipment used for AMS is almost exclusively based on the electrostatic tandem accelerator, although some of the newest systems are based on a slightly different principle. Dedicated accelerators as well as older "nuclear physics machines" can be found in the 80 or so AMS laboratories in existence today. The most widely used isotope studied with AMS is 14C. Besides radiocarbon dating this isotope is used in climate studies, biomedicine applications and many other fields. More than 100,000 14C samples are measured per year. Other isotopes studied include 10Be, 26Al, 36Cl, 41Ca, 59Ni, 129I, U, and Pu. Although these measurements are important, the number of samples of these other isotopes measured each year is estimated to be less than 10% of the number of 14C samples. Copyright 2008 Wiley Periodicals, Inc.

  10. Holograms for the Masses

    International Nuclear Information System (INIS)

    Newswanger, Craig; Klug, Michael

    2013-01-01

    Traditional holography subject matter has been generally limited to small dead things (SMD). Pulse lasers and the advent of holographic stereography have made it easier to make holograms of scaled objects and those that live (un-SMD), at a cost of single dimensional parallax or monochromaticity. While stunning results have been produced, all of these required access to a lab, expensive lasers and optics, and infinite patience, care and skill to collect and record content. This complexity has generally kept holography out of reach for the masses. The recent introduction of new 3D data sources, free or inexpensive composition and editing software, and fast, consistent print services may make it possible to finally 'democratize' holography, and enable image makers to focus on message rather than medium. This paper will outline several photogrammetry-based methods for producing 3D content for holograms (with a camera and mouse finger), software applications for editing, positioning and lighting, and production means that are usable by anyone, from novice to professional. We will present step-by-step examples and display results depicting various subject matter, from color holographic portraits made from smart phone input to holographic maps made from movies collected with remote control airplanes. The aim is to inspire image making, spontaneity, and maybe even social media-based collaboration to make EVERYONE a holographer.

  11. Lung Mass in Smokers.

    Science.gov (United States)

    Washko, George R; Kinney, Gregory L; Ross, James C; San José Estépar, Raúl; Han, MeiLan K; Dransfield, Mark T; Kim, Victor; Hatabu, Hiroto; Come, Carolyn E; Bowler, Russell P; Silverman, Edwin K; Crapo, James; Lynch, David A; Hokanson, John; Diaz, Alejandro A

    2017-04-01

    Emphysema is characterized by airspace dilation, inflammation, and irregular deposition of elastin and collagen in the interstitium. Computed tomographic studies have reported that lung mass (LM) may be increased in smokers, a finding attributed to inflammatory and parenchymal remodeling processes observed on histopathology. We sought to examine the epidemiologic and clinical associations of LM in smokers. Baseline epidemiologic, clinical, and computed tomography (CT) data (n = 8156) from smokers enrolled into the COPDGene Study were analyzed. LM was calculated from the CT scan. Changes in lung function at 5 years' follow-up were available from 1623 subjects. Regression analysis was performed to assess for associations of LM with forced expiratory volume in 1 second (FEV 1 ) and FEV 1 decline. Subjects with Global Initiative for Chronic Obstructive Lung Disease (GOLD) 1 chronic obstructive pulmonary disease had greater LM than either smokers with normal lung function or those with GOLD 2-4 chronic obstructive pulmonary disease (P smokers: the presence of such nonlinearity must be accounted for in longitudinal computed tomographic studies. Baseline LM predicts the decline in lung function. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  12. Mass media tours Bangladesh.

    Science.gov (United States)

    1998-07-01

    In May 1998, representatives of Japan's mass media toured Bangladesh to learn about the country's reproductive health and population programs. The goal of the visit was for the journalists to spread information about the projects to their peers, to government officials, and parliamentarians responsible for allocations of foreign aid. The 1st stage of the visit involved meetings with program officials and organizers. In the 2nd stage, the journalists toured: 1) Matlab, where the International Center for Diarrhoeal Disease Research has been implementing an intensive family planning (FP) program; 2) the Panchdona IP area, where the Integrated Family Development Project is being conducted with funding from the Japanese government; 3) an FP office and satellite clinic; and 4) a site where voluntary organizations are providing FP/maternal-child health care. The journalists also learned about how micro-credit loans operate. Participating journalists reported that they were very impressed with the people of Bangladesh, and that they had gained a new understanding of the relationship between reproductive health and human rights.

  13. Severe dyspnea due to a giant antrochoanal polyp

    OpenAIRE

    Coloma-Milano M; Gil-Carcedo-Sañudo E; Gil-Carcedo-García LM.; Martín-Batista S; Madrigal-Revuelta M; Vallejo-Valdezate LA

    2012-01-01

    SummaryIntroduction: The antrochoanal polyp is a prevalent pathology in teenagers and young adults. It usually presents with nasal obstruction.Patient and method: Case report: An 80-year-old male with alcoholic encephalopathy, chronic bronchial disease of unknown etiology and polypoid chronic rhinosinusitis came to the emergency service with severe dyspnea without laryngeal features.Anterior rhinoscopy showed a polypoid mass in left nostril that prevented the visualization with nasal endoscop...

  14. Ectopic Thymic Cyst of the Subglottis: Considerations for Diagnosis and Management.

    Science.gov (United States)

    Ahmad, Iram; Kirby, Patricia; Liming, Bryan

    2018-03-01

    To share the diagnostic and management challenges created by an extremely rare airway lesion-the subglottic ectopic thymic cyst. Case report and literature review. We review the presentation, management, and clinical course of an infant who presented with a subglottic mass that was histologically confirmed as a thymic cyst. A brief literature review supplements the case presentation Results: We present the third described case of an ectopic thymic cyst presenting as a subglottic mass. The differential diagnosis of subglottic masses in neonates consists primarily of subglottic hemangioma and mucous retention cysts. Otolaryngologists must be prepared for unexpected findings when dealing with critical airways. We compare the presentation and management of our patient with the 2 previously described cases. We propose an embryologic theory for the origin of these rare lesions. An ectopic thymic cyst is a rare and unexpected cause of neonatal stridor. Management of pediatric airway lesions must allow for unexpected findings at the time of diagnostic and therapeutic endoscopy. The appropriate management of subglottic thymic cysts is poorly defined, but close surveillance for recurrence is mandatory.

  15. Mini ion trap mass spectrometer

    Science.gov (United States)

    Dietrich, D.D.; Keville, R.F.

    1995-09-19

    An ion trap is described which operates in the regime between research ion traps which can detect ions with a mass resolution of better than 1:10{sup 9} and commercial mass spectrometers requiring 10{sup 4} ions with resolutions of a few hundred. The power consumption is kept to a minimum by the use of permanent magnets and a novel electron gun design. By Fourier analyzing the ion cyclotron resonance signals induced in the trap electrodes, a complete mass spectra in a single combined structure can be detected. An attribute of the ion trap mass spectrometer is that overall system size is drastically reduced due to combining a unique electron source and mass analyzer/detector in a single device. This enables portable low power mass spectrometers for the detection of environmental pollutants or illicit substances, as well as sensors for on board diagnostics to monitor engine performance or for active feedback in any process involving exhausting waste products. 10 figs.

  16. Heavy quark hadron mass scale

    International Nuclear Information System (INIS)

    Anderson, J.T.

    1994-01-01

    Without the spin interactions the hardron masses within a multiplet are degenerate. The light quark hadron degenerate mulitplet mass spectrum is extended from the 3 quark ground state multiplets at J P =0 - , 1/2 + , 1 - to include the excited states which follow the spinorial decomposition of SU(2)xSU(2). The mass scales for the 4, 5, 6, .. quark hadrons are obtained from the degenerate multiplet mass m 0 /M=n 2 /α with n=4, 5, 6, .. The 4, 5, 6, .. quark hadron degenerate multiplet masses follow by splitting of the heavy quark mass scales according to the spinorial decomposition of SU(2)xSU(2). (orig.)

  17. Video Games as Mass Art

    Directory of Open Access Journals (Sweden)

    Grant Tavinor

    2011-01-01

    Full Text Available Videogames are one of the most significant developments in the mass arts of recent times. In commercial terms, they are now among the most prominent of the mass arts worldwide. This commercial and cultural success does not exhaust the interest in videogames as a mass art phenomenon because games such as Grand Theft Auto IV and Fallout 3 are structurally radically different from previous forms of mass art. In particular, the ontology of videogames, the nature and identity of their works, and how they are instanced and evaluated is a departure from the familiar mass arts of film and popular music. This paper explores these differences in an attempt to fit videogames into a theory of mass art, but also to provide guidance on the issues of criticism and evaluation that surely follow from their ontological distinctiveness.

  18. Mass loss from S stars

    International Nuclear Information System (INIS)

    Jura, M.

    1988-01-01

    The mass-loss process in S stars is studied using 65 S stars from the listing of Wing and Yorka (1977). The role of pulsations in the mass-loss process is examined. It is detected that stars with larger mass-loss rates have a greater amplitude of pulsations. The dust-to-gas ratio for the S stars is estimated as 0.002 and the average mass-loss rate is about 6 x 10 to the -8th solar masses/yr. Some of the properties of the S stars, such as scale height, surface density, and lifetime, are measured. It is determined that scale height is 200 pc; the total duration of the S star phase is greater than or equal to 30,000 yr; and the stars inject 3 x 10 to the -6th solar masses/sq kpc yr into the interstellar medium. 46 references

  19. The neutron star mass distribution

    Energy Technology Data Exchange (ETDEWEB)

    Kiziltan, Bülent [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Kottas, Athanasios; De Yoreo, Maria [Department of Applied Mathematics and Statistics, University of California, Santa Cruz, CA 95064 (United States); Thorsett, Stephen E., E-mail: bkiziltan@cfa.harvard.edu [Department of Astronomy and Astrophysics, University of California and UCO/Lick Observatory, Santa Cruz, CA 95064 (United States)

    2013-11-20

    In recent years, the number of pulsars with secure mass measurements has increased to a level that allows us to probe the underlying neutron star (NS) mass distribution in detail. We critically review the radio pulsar mass measurements. For the first time, we are able to analyze a sizable population of NSs with a flexible modeling approach that can effectively accommodate a skewed underlying distribution and asymmetric measurement errors. We find that NSs that have evolved through different evolutionary paths reflect distinctive signatures through dissimilar distribution peak and mass cutoff values. NSs in double NS and NS-white dwarf (WD) systems show consistent respective peaks at 1.33 M {sub ☉} and 1.55 M {sub ☉}, suggesting significant mass accretion (Δm ≈ 0.22 M {sub ☉}) has occurred during the spin-up phase. The width of the mass distribution implied by double NS systems is indicative of a tight initial mass function while the inferred mass range is significantly wider for NSs that have gone through recycling. We find a mass cutoff at ∼2.1 M {sub ☉} for NSs with WD companions, which establishes a firm lower bound for the maximum NS mass. This rules out the majority of strange quark and soft equation of state models as viable configurations for NS matter. The lack of truncation close to the maximum mass cutoff along with the skewed nature of the inferred mass distribution both enforce the suggestion that the 2.1 M {sub ☉} limit is set by evolutionary constraints rather than nuclear physics or general relativity, and the existence of rare supermassive NSs is possible.

  20. Cosmological origin of mass scales

    International Nuclear Information System (INIS)

    Terazawa, H.

    1981-01-01

    We discuss the possibility that spontaneous breakdown of conformal invariance due to the very existence of our universe originates all the mass (or length) scales ranging from the Planck mass (approx. 10 19 GeV) to the Hubble constant (approx. 10 -42 GeV) and suggest that the photon may have a curvature-dependent mass which is as small as 10 -42 GeV. We also present a possible clue to Dirac's large number hypothesis. (orig.)

  1. Cosmological origin of mass scales

    International Nuclear Information System (INIS)

    Terazawa, Hidezumi.

    1981-02-01

    We discuss the possibility that spontaneous breakdown of conformal invariance due to the very existence of our universe originates all the mass (or length) scales ranging from the Planck mass (--10 19 GeV) to the Hubble constant (--10 -42 GeV) and suggest that the photon may have a curvature-dependent mass which is as small as 10 -42 GeV. We also present a possible clue to the Dirac's large number hypothesis. (author)

  2. Adnexal mass in tubal pregnancy

    International Nuclear Information System (INIS)

    Lee, Hee Jung; Kim, Jung Sik; Chu, Yang Ku

    1993-01-01

    Off the evaluation of clinical significance and pathologic correlation of echogenic adnexal mass in tubal pregnancy, which is separated from ipsilateral ovary, we performed a retrospective analysis of 15 proved tubal pregnancies. All showed hematosalpinx containing blood coagulum and chorionic villi with intact fallopian tube.The echogenicity of the adnexal mass was considered to represent the nonclotted or clotted blood within the fallopian tube. We conclude that the discrete, echogenic adnexal mass is the suggestive finding of unrupturedtubal pregnancy

  3. Limits on the photon mass

    International Nuclear Information System (INIS)

    Vasseur, G.

    1996-03-01

    Is the photon mass strictly null as it is told in quantum electrodynamics. In fact, a coherent theory can be build with a massive photon. Experiences have been regularly led to try to make obvious an eventual non null photon mass. Superior limits more and more strict have been found. Here is given a general survey of the consequences of a non null photon mass, different methods to measure it and the achieved limits. (author). 30 refs., 1 fig

  4. The magnetic centrifugal mass filter

    International Nuclear Information System (INIS)

    Fetterman, Abraham J.; Fisch, Nathaniel J.

    2011-01-01

    Mass filters using rotating plasmas have been considered for separating nuclear waste and spent nuclear fuel. We propose a new mass filter that utilizes centrifugal and magnetic confinement of ions in a way similar to the asymmetric centrifugal trap. This magnetic centrifugal mass filter is shown to be more proliferation resistant than present technology. This filter is collisional and produces well confined output streams, among other advantages.

  5. The magnetic centrifugal mass filter

    Energy Technology Data Exchange (ETDEWEB)

    Fetterman, Abraham J.; Fisch, Nathaniel J. [Department of Astrophysical Sciences, Princeton University, Princeton, New Jersey 08540 (United States)

    2011-09-15

    Mass filters using rotating plasmas have been considered for separating nuclear waste and spent nuclear fuel. We propose a new mass filter that utilizes centrifugal and magnetic confinement of ions in a way similar to the asymmetric centrifugal trap. This magnetic centrifugal mass filter is shown to be more proliferation resistant than present technology. This filter is collisional and produces well confined output streams, among other advantages.

  6. Luxury for the masses.

    Science.gov (United States)

    Silverstein, Michael J; Fiske, Neil

    2003-04-01

    Increasingly wide income disparities, higher levels of education, and greater awareness of other cultures' ideas of the good life have given rise to a new class of American consumer. And a new category of products and services, including automobiles, apparel, food, wine, and spirits, has sprung into being to cater to it. That category is called new luxury. America's middle-market consumers are trading up to higher levels of quality and taste than ever before. Members of the middle market (those earning $50,000 and above annually) collectively have around $1 trillion of disposable income. And they will pay premiums of 20% to 200% for well-designed, well-engineered, and well-crafted goods that can't be found in the mass middle market and that have the artisanal touches of traditional luxury items. Most important, even when they address basic necessities, such goods evoke and engage consumers' emotions while feeding their aspirations for a better life. Supply-side forces are essential to the rise of new luxury. Like the consumers of their goods, entrepreneurs are better educated and more sophisticated about their customers than ever before. In addition, global sourcing, falling trade barriers and transportation costs, and rising offshore manufacturing standards are making possible the economical production of alluring products of high quality. Unlike old-luxury goods, new-luxury products can generate high sales volumes despite their relatively high prices. As a result, new-luxury companies are achieving levels of profitability and growth beyond the reach of their conventional competitors. Whether the item in question is a $6 Panera sandwich or a $30,000 Mercedes, new luxury is a formula that middle-market companies, facing erosion of their market share by high-end and low-end producers, can ill afford to ignore.

  7. LADEE Neutral Mass Spectrometer Data

    Data.gov (United States)

    National Aeronautics and Space Administration — This bundle contains the data collected by the Neutral Mass Spectrometer (NMS) instrument aboard the Lunar Atmosphere and Dust Environment Explorer (LADEE)...

  8. Mass loss from Eta Carinae

    International Nuclear Information System (INIS)

    Andriesse, C.D.; Viotti, R.

    1979-01-01

    This high luminosity (5x10 6 solar luminosity) star since 1840 is losing mass at the rate of 7.5x10 -2 solar masses per year. The large mass loss could be the result of vibrational instabilities produced in the CNO hydrogen burning phase of a very massive (160 solar masses) star. The presence of high excitation lines in the ultraviolet spectrum of Eta Car suggests the idea of a hot zone excited by dissipation of the supersonic turbulent flow. (Auth.)

  9. Vortex mass in a superfluid

    Science.gov (United States)

    Simula, Tapio

    2018-02-01

    We consider the inertial mass of a vortex in a superfluid. We obtain a vortex mass that is well defined and is determined microscopically and self-consistently by the elementary excitation energy of the kelvon quasiparticle localized within the vortex core. The obtained result for the vortex mass is found to be consistent with experimental observations on superfluid quantum gases and vortex rings in water. We propose a method to measure the inertial rest mass and Berry phase of a vortex in superfluid Bose and Fermi gases.

  10. Review of atomic mass formula

    Energy Technology Data Exchange (ETDEWEB)

    Tachibana, Takahiro [Waseda Univ., Tokyo (Japan). Advanced Research Center for Science and Engineering

    1997-07-01

    Wapstra and Audi`s Table is famous for evaluation of experimental data of atomic nuclear masses (1993/1995 version) which estimated about 2000 kinds of nuclei. The error of atomic mass of formula is 0.3 MeV-0.8 MeV. Four kinds of atomic mass formula: JM (Jaenecke and Masson), TUYY (Tachibana, Uno, Yamada and Yamada), FRDM (Moeller, Nix, Myers and Swiatecki) and ETFSI (Aboussir, Pearson, Dutta and Tondeur) and their properties (number of parameter and error etc.) were explained. An estimation method of theoretical error of mass formula was presented. It was estimated by the theoretical error of other surrounding nuclei. (S.Y.)

  11. Simulating at realistic quark masses. Light quark masses

    International Nuclear Information System (INIS)

    Goeckeler, M.; Streuer, T.

    2006-11-01

    We present new results for light quark masses. The calculations are performed using two flavours of O(a) improved Wilson fermions. We have reached lattice spacings as small as a ∝0.07 fm and pion masses down to m π ∝340 MeV in our simulations. This gives us significantly better control on the chiral and continuum extrapolations. (orig.)

  12. Mass-shell properties of the dynamical quark mass

    International Nuclear Information System (INIS)

    Reinders, L.J.; Stam, K.

    1986-07-01

    We discuss the running dynamical quark mass in the framework of the operator product expansion. It is shown that for vertical strokep 2 vertical stroke>m 2 the quark-condensate part of the quark self energy has no contributions of order m 2 or higher, and is frozen to its mass-shell value for smaller vertical strokep 2 vertical stroke. (orig.)

  13. Atomic masses 1995. The 1995 atomic mass evaluation

    International Nuclear Information System (INIS)

    Audi, G.; Wapstra, A.H.

    1995-01-01

    The 1995 atomic mass evaluation by G. Audi and A.H. Wapstra is documented. The resulting data files containing recommended values of atomic masses, obtained by experiment or systematics, and related data such as reaction and separation energies are described. The data files can be obtained through online services from several nuclear data centers or on magnetic tape, free of charge. (author)

  14. Atomic masses 1993. The 1993 atomic mass evaluation

    International Nuclear Information System (INIS)

    Audi, G.; Wapstra, A.H.

    1993-01-01

    The 1993 atomic mass evaluation by G. Audi and A.H. Wapstra is documented. The resulting data files containing recommended values of atomic masses, obtained by experiment of systematics, and related data such as reaction and separation energies are described. The data files can be obtained through online services from several nuclear data centers or on magnetic tape, free of charge. (author)

  15. Maximally twisted mass lattice QCD at the physical pion mass

    International Nuclear Information System (INIS)

    Kostrzewa, Bartosz

    2016-01-01

    In computer simulations of Lattice Quantum Chromodynamics, the usage of unphysically large quark masses and the subsequent extrapolation of results to the physical value of the quark masses are major sources of systematic uncertainty. In this thesis, the feasibility and practicality of numerical simulations of Quantum Chromodynamics with physically light up and down quarks using the Wilson twisted mass quark discretisation are explored. Working in this regime is complicated firstly by the numerical expense of these simulations and secondly by the presence of potentially large lattice artefacts. The twisted mass discretisation is affected by an unphysical mass difference between the charged and neutral pions, rendering simulations at the physical charged pion mass infeasible if this mass splitting is too large. With the aim of reducing it, the Sheikholeslami-Wohlert term is added to the twisted mass fermion action and simulations with mass degenerate up and down quarks are then performed as a proof of concept. It is demonstrated that these simulations are stable and that the parameters of the lattice theory can be successfully tuned to correspond to the physical charged pion mass. Subsequently, the parameter tuning for simulations with mass degenerate up and down quarks as well as strange and charm quarks is explored and it is shown that it can be carried out in steps. As benchmark observables, the masses and decay constants of pseudoscalar mesons with light, strange and charm valence quarks are calculated and seen to largely reproduce their phenomenological values, even though continuum and infinite volume extrapolations are not performed. Light, strange and charm quark mass estimates are determined based on this data and also seen to coincide with phenomenological and other lattice determinations. In this analysis, a particular emphasis is placed on the systematic error due to the choice of fit range for pseudoscalar correlation functions and a weighting method is

  16. Neutrino mass, a status report

    International Nuclear Information System (INIS)

    Robertson, R.G.H.

    1993-01-01

    Experimental approaches to neutrino mass include kinematic mass measurements, neutrino oscillation searches at rectors and accelerators, solar neutrinos, atmospheric neutrinos, and single and double beta decay. The solar neutrino results yield fairly strong and consistent indications that neutrino oscillations are occurring. Other evidence for new physics is less consistent and convincing

  17. Mass Mentality, Culture Industry, Fascism

    Directory of Open Access Journals (Sweden)

    Saladdin Said Ahmed

    2008-06-01

    Full Text Available Some fashionable leftist movements and populist intellectuals habitually blame the sources of information for public ignorance about the miserable state of the world. It could be argued, however, that the masses are ignorant because they prefer ignorance. A mass individual is politically apathetic and intellectually lazy. As a result, even when huge amounts of information are available, which is the case in this epoch, the masses insist on choosing ignorance. It is true that there is not enough information about what has happened in a place such as Darfur, but the masses choose not to access even the amount of information that is available. The great majority of people in China, Iran, and America, despite the fact that they have varying amounts of access to various types of "knowledge," still tend to be misinformed. It seems that a mass individual is curious only about what directly affects his/her own personal life. I will explore the connection between mass mentality and the culture industry in order to capture the essential role of the former in the latter. I will also argue that a mass individual is the source of fascism although fascism as a phenomenon needs a mass culture in which to flourish.

  18. Preface Miniaturization and Mass Spectrometry

    NARCIS (Netherlands)

    Unknown, [Unknown; le Gac, Severine; le Gac, S.; van den Berg, Albert; van den Berg, A.

    2009-01-01

    Miniaturization and Mass Spectrometry illustrates this trend and focuses on one particular analysis technique, mass spectrometry whose popularity has "dramatically" increased in the last two decades with the explosion of the field of biological analysis and the development of two "soft" ionization

  19. Imaging mass spectrometry statistical analysis.

    Science.gov (United States)

    Jones, Emrys A; Deininger, Sören-Oliver; Hogendoorn, Pancras C W; Deelder, André M; McDonnell, Liam A

    2012-08-30

    Imaging mass spectrometry is increasingly used to identify new candidate biomarkers. This clinical application of imaging mass spectrometry is highly multidisciplinary: expertise in mass spectrometry is necessary to acquire high quality data, histology is required to accurately label the origin of each pixel's mass spectrum, disease biology is necessary to understand the potential meaning of the imaging mass spectrometry results, and statistics to assess the confidence of any findings. Imaging mass spectrometry data analysis is further complicated because of the unique nature of the data (within the mass spectrometry field); several of the assumptions implicit in the analysis of LC-MS/profiling datasets are not applicable to imaging. The very large size of imaging datasets and the reporting of many data analysis routines, combined with inadequate training and accessible reviews, have exacerbated this problem. In this paper we provide an accessible review of the nature of imaging data and the different strategies by which the data may be analyzed. Particular attention is paid to the assumptions of the data analysis routines to ensure that the reader is apprised of their correct usage in imaging mass spectrometry research. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. Maximum stellar iron core mass

    Indian Academy of Sciences (India)

    An analytical method of estimating the mass of a stellar iron core, just prior to core collapse, is described in this paper. The method employed depends, in part, upon an estimate of the true relativistic mass increase experienced by electrons within a highly compressed iron core, just prior to core collapse, and is significantly ...

  1. Mass Notification for Higher Education

    Science.gov (United States)

    Schneider, Tod

    2010-01-01

    Mass notification is a high priority in educational institutions. As the number of electronic communication devices has diversified, so has the complexity of designing an effective mass notification system. Picking the right system, with the right features, support services and price, can be daunting. This publication, updated quarterly due to…

  2. Black-Hole Mass Measurements

    DEFF Research Database (Denmark)

    Vestergaard, Marianne

    2004-01-01

    The applicability and apparent uncertainties of the techniques currently available for measuring or estimating black-hole masses in AGNs are briefly summarized.......The applicability and apparent uncertainties of the techniques currently available for measuring or estimating black-hole masses in AGNs are briefly summarized....

  3. An Empirical Mass Function Distribution

    Science.gov (United States)

    Murray, S. G.; Robotham, A. S. G.; Power, C.

    2018-03-01

    The halo mass function, encoding the comoving number density of dark matter halos of a given mass, plays a key role in understanding the formation and evolution of galaxies. As such, it is a key goal of current and future deep optical surveys to constrain the mass function down to mass scales that typically host {L}\\star galaxies. Motivated by the proven accuracy of Press–Schechter-type mass functions, we introduce a related but purely empirical form consistent with standard formulae to better than 4% in the medium-mass regime, {10}10{--}{10}13 {h}-1 {M}ȯ . In particular, our form consists of four parameters, each of which has a simple interpretation, and can be directly related to parameters of the galaxy distribution, such as {L}\\star . Using this form within a hierarchical Bayesian likelihood model, we show how individual mass-measurement errors can be successfully included in a typical analysis, while accounting for Eddington bias. We apply our form to a question of survey design in the context of a semi-realistic data model, illustrating how it can be used to obtain optimal balance between survey depth and angular coverage for constraints on mass function parameters. Open-source Python and R codes to apply our new form are provided at http://mrpy.readthedocs.org and https://cran.r-project.org/web/packages/tggd/index.html respectively.

  4. Negative chemical ionization mass spectrometry

    International Nuclear Information System (INIS)

    Smit, A.L.C.

    1979-01-01

    This thesis describes some aspects of Negative Chemical Ionization (NCI) mass spectrometry. The reasons for the growing interest in NCI are: (i) to extend the basic knowledge of negative ions and their reactions in the gas phase; (ii) to investigate whether or not this knowledge of negative ions can be used successfully to elucidate the structure of molecules by mass spectrometry. (Auth.)

  5. Longitudinal bulk acoustic mass sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Teva, Jordi; Boisen, Anja

    2009-01-01

    A polycrystalline silicon longitudinal bulk acoustic cantilever is fabricated and operated in air at 51 MHz. A mass sensitivity of 100 Hz/fg (1 fg=10(-15) g) is obtained from the preliminary experiments where a minute mass is deposited on the device by means of focused ion beam. The total noise...

  6. Digital Integration: Towards Mass Customization

    DEFF Research Database (Denmark)

    Schou, Finn

    Mass production in lots of one” is a phrase coined by Oliver Morton in a seminal piece for The Economist (1994). In few words this sentence contains the essence (and schism) of true customization aiming at manufacturing the artifact for the mass. Emerging Nanotechnologies are said to enable...

  7. Laboratory of acceleration mass spectrometry

    International Nuclear Information System (INIS)

    Hybler, P.; Chrapan, J.

    2002-01-01

    In this paper authors describe the principle of the method of acceleration mass spectrometry and the construction plans of this instrument at the Faculty of ecology and environmental sciences in Banska Stiavnica. Using of this instrument for radiocarbon dating is discussed. A review of laboratories with acceleration mass spectrometry is presented

  8. Understanding neutrino masses and mixings

    Indian Academy of Sciences (India)

    various possible oscillation solutions to the solar neutrino puzzle. It seems .... A first hint of this new ingredient came from the observation of Weinberg that if ..... Using the discussion of the above paragraph, the Dirac mass of the neutrino as .... that contributes to charged fermion masses, one can write the quark and lepton.

  9. Cluster secondary ion mass spectrometry microscope mode mass spectrometry imaging.

    Science.gov (United States)

    Kiss, András; Smith, Donald F; Jungmann, Julia H; Heeren, Ron M A

    2013-12-30

    Microscope mode imaging for secondary ion mass spectrometry is a technique with the promise of simultaneous high spatial resolution and high-speed imaging of biomolecules from complex surfaces. Technological developments such as new position-sensitive detectors, in combination with polyatomic primary ion sources, are required to exploit the full potential of microscope mode mass spectrometry imaging, i.e. to efficiently push the limits of ultra-high spatial resolution, sample throughput and sensitivity. In this work, a C60 primary source was combined with a commercial mass microscope for microscope mode secondary ion mass spectrometry imaging. The detector setup is a pixelated detector from the Medipix/Timepix family with high-voltage post-acceleration capabilities. The system's mass spectral and imaging performance is tested with various benchmark samples and thin tissue sections. The high secondary ion yield (with respect to 'traditional' monatomic primary ion sources) of the C60 primary ion source and the increased sensitivity of the high voltage detector setup improve microscope mode secondary ion mass spectrometry imaging. The analysis time and the signal-to-noise ratio are improved compared with other microscope mode imaging systems, all at high spatial resolution. We have demonstrated the unique capabilities of a C60 ion microscope with a Timepix detector for high spatial resolution microscope mode secondary ion mass spectrometry imaging. Copyright © 2013 John Wiley & Sons, Ltd.

  10. Status of neutrino mass experiments

    International Nuclear Information System (INIS)

    Fackler, O.

    1985-01-01

    In 1980 two experiments ignited a fertile field of research - the determination of the neutrino masses. Subsequently, over 35 experiments using a variety of techniques have probed or are probing this question. Primarily the author discuss electron antineutrino (hereafter referred to as neutrino) mass experiments. Section I begins with a discussion of astronomical and terrestrial observations which motivated these experiments. In Section II, the author quote limits from muon and tau mass determinations. These limits are more thoroughly discussed in other paper. The author continues by describing the four approaches used to measure the electron neutrino mass. In Section III, tritium beta decay mass determinations are reviewed. This section includes a general summary of previous experimental results, and discussion of the major ongoing experiments. Section IV offers concluding remarks

  11. Computational force, mass, and energy

    International Nuclear Information System (INIS)

    Numrich, R.W.

    1997-01-01

    This paper describes a correspondence between computational quantities commonly used to report computer performance measurements and mechanical quantities from classical Newtonian mechanics. It defines a set of three fundamental computational quantities that are sufficient to establish a system of computational measurement. From these quantities, it defines derived computational quantities that have analogous physical counterparts. These computational quantities obey three laws of motion in computational space. The solutions to the equations of motion, with appropriate boundary conditions, determine the computational mass of the computer. Computational forces, with magnitudes specific to each instruction and to each computer, overcome the inertia represented by this mass. The paper suggests normalizing the computational mass scale by picking the mass of a register on the CRAY-1 as the standard unit of mass

  12. Status of neutrino mass experiments

    International Nuclear Information System (INIS)

    Fackler, O.

    1985-12-01

    In 1980 two experiments ignited a fertile field of research the determination of the neutrino masses. Subsequently, over 35 experiments using a variety of techniques have probed or are probing this question. Primarily I will discuss electron antineutrino (hereafter referred to as neutrino) mass experiments. However, let me begin in Section I to discuss astronomical and terrestrial observations which motivated these experiments. In Section II, I will quote limits from muon and tau mass determinations. These limits are more thoroughly discussed in other papers. I will continue by describing the four approaches used to measure the electron neutrino mass. In Section III, tritium beta decay mass determinations will be reviewed. This section includes a general summary of previous experimental results, and discussion of the major ongoing experiments. Section IV offers concluding remarks. 24 refs., 24 figs

  13. Mass spectrometry. [in organic chemistry

    Science.gov (United States)

    Burlingame, A. L.; Shackleton, C. H. L.; Howe, I.; Chizhov, O. S.

    1978-01-01

    A review of mass spectrometry in organic chemistry is given, dealing with advances in instrumentation and computer techniques, selected topics in gas-phase ion chemistry, and applications in such fields as biomedicine, natural-product studies, and environmental pollution analysis. Innovative techniques and instrumentation are discussed, along with chromatographic-mass spectrometric on-line computer techniques, mass spectral interpretation and management techniques, and such topics in gas-phase ion chemistry as electron-impact ionization and decomposition, photoionization, field ionization and desorption, high-pressure mass spectrometry, ion cyclotron resonance, and isomerization reactions of organic ions. Applications of mass spectrometry are examined with respect to bio-oligomers and their constituents, biomedically important substances, microbiology, environmental organic analysis, and organic geochemistry.

  14. Conjugate heat and mass transfer in heat mass exchanger ducts

    CERN Document Server

    Zhang, Li-Zhi

    2013-01-01

    Conjugate Heat and Mass Transfer in Heat Mass Exchanger Ducts bridges the gap between fundamentals and recent discoveries, making it a valuable tool for anyone looking to expand their knowledge of heat exchangers. The first book on the market to cover conjugate heat and mass transfer in heat exchangers, author Li-Zhi Zhang goes beyond the basics to cover recent advancements in equipment for energy use and environmental control (such as heat and moisture recovery ventilators, hollow fiber membrane modules for humidification/dehumidification, membrane modules for air purification, desi

  15. Correcting mass shifts: A lock mass-free recalibration procedure for mass spectrometry imaging data

    Czech Academy of Sciences Publication Activity Database

    Kulkarni, P.; Kaftan, F.; Kynast, P.; Svatoš, Aleš; Böcker, S.

    2015-01-01

    Roč. 407, č. 25 (2015), s. 7603-7613 ISSN 1618-2642 Institutional support: RVO:61388963 Keywords : mass spectrometry imaging * recalibration * mass shift correction * data processing Subject RIV: CB - Analytical Chemistry , Separation Impact factor: 3.125, year: 2015

  16. Precise atomic mass measurements by deflection mass spectrometry

    CERN Document Server

    Barber, R C

    2003-01-01

    Since its inception nearly 90 years ago by J.J. Thomson, the precise determination of atomic masses by the classical technique of deflecting charged particles in electric and magnetic fields has provided a large body of data on naturally occurring nuclides. Currently, such measurements on stable nuclides have frequently achieved a precision of better than two parts in 10 sup 9 of the mass. A review of the technique, together with a brief summary of the important historical developments in the field of precise atomic mass measurements, will be given. The more recent contributions to this field by the deflection mass spectrometer at the University of Manitoba will be provided as illustrations of the culmination of the techniques used and the applications that have been studied. A brief comparison between this and newer techniques using Penning traps will be presented.

  17. Dynamics of Variable Mass Systems

    Science.gov (United States)

    Eke, Fidelis O.

    1998-01-01

    This report presents the results of an investigation of the effects of mass loss on the attitude behavior of spinning bodies in flight. The principal goal is to determine whether there are circumstances under which the motion of variable mass systems can become unstable in the sense that their transverse angular velocities become unbounded. Obviously, results from a study of this kind would find immediate application in the aerospace field. The first part of this study features a complete and mathematically rigorous derivation of a set of equations that govern both the translational and rotational motions of general variable mass systems. The remainder of the study is then devoted to the application of the equations obtained to a systematic investigation of the effect of various mass loss scenarios on the dynamics of increasingly complex models of variable mass systems. It is found that mass loss can have a major impact on the dynamics of mechanical systems, including a possible change in the systems stability picture. Factors such as nozzle geometry, combustion chamber geometry, propellant's initial shape, size and relative mass, and propellant location can all have important influences on the system's dynamic behavior. The relative importance of these parameters on-system motion are quantified in a way that is useful for design purposes.

  18. Overview of the mass measurements

    International Nuclear Information System (INIS)

    Shull, L.M.

    1991-01-01

    a three-day mass measurement workshop conference sponsored by the INMM was held April 22-24, 1991, in Atlanta, Georgia. DOE Order 5633.3 requires mass measurement control programs for the measurements of nuclear materials but provides little guidance on details for these programs. Measurement principles used for mass are often applicable to other physical property measurements. Westinghouse Savannah River Site (WSRS) personnel organized the workshop conference to facilitate the transfer of mass measurement technology and establish better communications between the calibration laboratories, manufactures, regulators, and scale and balance users in the mass measurement community. Three different formats were used to present the information: a seminar, individual papers, and workshops. The seminar topic was the Process Measurement Assurance Program (PMAP), developed by EG and G Mound Applied Technologies, for determining and controlling measurement errors in manufacturing processes. Paper and workshop topics included: Mass Measurement Techniques and Programs, Selection of equipment and Standards, Standards and Traceability, and Automation in Mass Measurement. The paper gives an overview of the workshop conference, including purpose, participants, and summaries of the seminar, paper, and workshops

  19. High-Resolution Mass Spectrometers

    Science.gov (United States)

    Marshall, Alan G.; Hendrickson, Christopher L.

    2008-07-01

    Over the past decade, mass spectrometry has been revolutionized by access to instruments of increasingly high mass-resolving power. For small molecules up to ˜400 Da (e.g., drugs, metabolites, and various natural organic mixtures ranging from foods to petroleum), it is possible to determine elemental compositions (CcHhNnOoSsPp…) of thousands of chemical components simultaneously from accurate mass measurements (the same can be done up to 1000 Da if additional information is included). At higher mass, it becomes possible to identify proteins (including posttranslational modifications) from proteolytic peptides, as well as lipids, glycoconjugates, and other biological components. At even higher mass (˜100,000 Da or higher), it is possible to characterize posttranslational modifications of intact proteins and to map the binding surfaces of large biomolecule complexes. Here we review the principles and techniques of the highest-resolution analytical mass spectrometers (time-of-flight and Fourier transform ion cyclotron resonance and orbitrap mass analyzers) and describe some representative high-resolution applications.

  20. Current Direct Neutrino Mass Experiments

    Directory of Open Access Journals (Sweden)

    G. Drexlin

    2013-01-01

    Full Text Available In this contribution, we review the status and perspectives of direct neutrino mass experiments, which investigate the kinematics of β-decays of specific isotopes (3H, 187Re, 163Ho to derive model-independent information on the averaged electron (antineutrino mass. After discussing the kinematics of β-decay and the determination of the neutrino mass, we give a brief overview of past neutrino mass measurements (SN1987a-ToF studies, Mainz and Troitsk experiments for 3H, cryobolometers for 187Re. We then describe the Karlsruhe Tritium Neutrino (KATRIN experiment currently under construction at Karlsruhe Institute of Technology, which will use the MAC-E-Filter principle to push the sensitivity down to a value of 200 meV (90% C.L.. To do so, many technological challenges have to be solved related to source intensity and stability, as well as precision energy analysis and low background rate close to the kinematic endpoint of tritium β-decay at 18.6 keV. We then review new approaches such as the MARE, ECHO, and Project8 experiments, which offer the promise to perform an independent measurement of the neutrino mass in the sub-eV region. Altogether, the novel methods developed in direct neutrino mass experiments will provide vital information on the absolute mass scale of neutrinos.

  1. Simulating at realistic quark masses. Light quark masses

    Energy Technology Data Exchange (ETDEWEB)

    Goeckeler, M. [Regensburg Univ. (Germany). Inst. fuer Physik 1 - Theoretische Physik; Horsley, R.; Zanotti, J.M. [Edinburgh Univ. (United Kingdom). School of Physics; Nakamura, Y.; Pleiter, D. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Dept. of Mathematical Sciences; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC]|[Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Streuer, T. [Kentucky Univ., Lexington, KY (United States). Dept. of Physics and Astronomy; Stueben, H. [Konrad-Zuse-Zentrum fuer Informationstechnik Berlin (ZIB) (Germany)

    2006-11-15

    We present new results for light quark masses. The calculations are performed using two flavours of O(a) improved Wilson fermions. We have reached lattice spacings as small as a {proportional_to}0.07 fm and pion masses down to m{sub {pi}} {proportional_to}340 MeV in our simulations. This gives us significantly better control on the chiral and continuum extrapolations. (orig.)

  2. Mass Properties for Space Systems Standards Development

    Science.gov (United States)

    Beech, Geoffrey

    2013-01-01

    Current Verbiage in S-120 Applies to Dry Mass. Mass Margin is difference between Required Mass and Predicted Mass. Performance Margin is difference between Predicted Performance and Required Performance. Performance estimates and corresponding margin should be based on Predicted Mass (and other inputs). Contractor Mass Margin reserved from Performance Margin. Remaining performance margin allocated according to mass partials. Compliance can be evaluated effectively by comparison of three areas (preferably on a single sheet). Basic and Predicted Mass (including historical trend). Aggregate potential changes (threats and opportunities) which gives Mass Forecast. Mass Maturity by category (Estimated/Calculated/Actual).

  3. Neutrino mass as the probe of intermediate mass scales

    International Nuclear Information System (INIS)

    Senjanovic, G.

    1980-01-01

    A discussion of the calculability of neutrino mass is presented. The possibility of neutrinos being either Dirac or Majorana particles is analyzed in detail. Arguments are offered in favor of the Majorana case: the smallness of neutrino mass is linked to the maximality of parity violation in weak interactions. It is shown how the measured value of neutrino mass would probe the existence of an intermediate mass scale, presumably in the TeV region, at which parity is supposed to become a good symmetry. Experimental consequences of the proposed scheme are discussed, in particular the neutrino-less double β decay, where observation would provide a crucial test of the model, and rare muon decays such as μ → eγ and μ → ee anti e. Finally, the embedding of this model in an O(10) grand unified theory is analyzed, with the emphasis on the implications for intermediate mass scales that it offers. It is concluded that the proposed scheme provides a distinct and testable alternative for understanding the smallness of neutrino mass. 4 figures

  4. Neutrino mass as the probe of intermediate mass scales

    Energy Technology Data Exchange (ETDEWEB)

    Senjanovic, G.

    1980-01-01

    A discussion of the calculability of neutrino mass is presented. The possibility of neutrinos being either Dirac or Majorana particles is analyzed in detail. Arguments are offered in favor of the Majorana case: the smallness of neutrino mass is linked to the maximality of parity violation in weak interactions. It is shown how the measured value of neutrino mass would probe the existence of an intermediate mass scale, presumably in the TeV region, at which parity is supposed to become a good symmetry. Experimental consequences of the proposed scheme are discussed, in particular the neutrino-less double ..beta.. decay, where observation would provide a crucial test of the model, and rare muon decays such as ..mu.. ..-->.. e..gamma.. and ..mu.. ..-->.. ee anti e. Finally, the embedding of this model in an O(10) grand unified theory is analyzed, with the emphasis on the implications for intermediate mass scales that it offers. It is concluded that the proposed scheme provides a distinct and testable alternative for understanding the smallness of neutrino mass. 4 figures.

  5. MASS CUSTOMIZATION and PRODUCT MODELS

    DEFF Research Database (Denmark)

    Svensson, Carsten; Malis, Martin

    2003-01-01

    to the product. Through the application of a mass customization strategy, companies have a unique opportunity to create increased customer satisfaction. In a customized production, knowledge and information have to be easily accessible since every product is a unique combination of information. If the dream...... of a customized alternative instead of a uniform mass-produced product shall become a reality, then the cross-organizational efficiency must be kept at a competitive level. This is the real challenge for mass customization. A radical restructuring of both the internal and the external knowledge management systems...

  6. The mass-lifetime relation

    Science.gov (United States)

    LoPresto, Michael C.

    2018-05-01

    In a recent "AstroNote," I described a simple exercise on the mass-luminosity relation for main sequence stars as an example of exposing students in a general education science course of lower mathematical level to the use of quantitative skills such as collecting and analyzing data. Here I present another attempt at a meaningful experience for such students that again involves both the gathering and analysis of numerical data and comparison with accepted result, this time on the relationship of the mass and lifetimes of main sequence stars. This experiment can stand alone or be used as an extension of the previous mass-luminosity relationship experiment.

  7. Mass loss and cepheid pulsation

    International Nuclear Information System (INIS)

    Davis, C.G. Jr.

    1977-01-01

    Two purposes are served: to discuss the latest improvements in nonlinear pulsation theory indicating the ability to resolve features such as the ''Christy bump'' on the light curves and to show from the results of a bump model and recent observations that mass loss is one of the possible explanations for the mass discrepancy problem between evolutionary and pulsation theories. Recent observations by Sanford and Gow of Los Alamos and Bernat (McDonald Observatory) show that extensive mass loss has occurred in the evolution of the M supergiant α Orionis

  8. Negative mass solitons in gravity

    International Nuclear Information System (INIS)

    Cebeci, Hakan; Sarioglu, Oezguer; Tekin, Bayram

    2006-01-01

    We first reconstruct the conserved (Abbott-Deser) charges in the spin-connection formalism of gravity for asymptotically (Anti)-de Sitter spaces, and then compute the masses of the AdS soliton and the recently found Eguchi-Hanson solitons in generic odd dimensions, unlike the previous result obtained for only five dimensions. These solutions have negative masses compared to the global AdS or AdS/Z p spacetimes. As a separate note, we also compute the masses of the recent even dimensional Taub-NUT-Reissner-Nordstroem metrics

  9. The Politics of Mass Digitization

    DEFF Research Database (Denmark)

    Thylstrup, Nanna Bonde

    Mass-digitization of cultural-heritage archives has become increasingly pervasive. From Google Books to Europeana, bounded material is converted into ephemeral data on an unprecedented scale, promising to provide mankind with readily accessible and enduring reservoirs of knowledge. Interrogating...... this phenomenon, this dissertation asks how mass digitization affects the politics of cultural heritage. Its central argument is that mass digitization of cultural heritage is neither a neutral technical process, nor a transposition of the politics of analog cultural heritage to the digital realm on a 1:1 scale....... Rather, it should be understood as distinct subpolitical processes that bring together a multiplicity of interests and actors hitherto foreign to the field of cultural heritage archives. Mass digitization is thus upheaving the disciplinary enclosures of cultural heritage and gives rise to new territorial...

  10. Mass Media and Political Participation

    Science.gov (United States)

    Lewellen, James R.

    1976-01-01

    Research reviews and statistical analysis of a specific study suggest that the mass media play a direct role in the political socialization of adolescents insofar as overt political behavior is concerned. (Author/AV)

  11. Mass screening in breast cancer

    International Nuclear Information System (INIS)

    Strax, P.

    1977-01-01

    Some questions about mass screening in breast cancer are answered it being concluded that: 1. mass screening for the detection of early breast cancer is the only means with proven potential for lowering the death rate of the disease; 2. mammography is an importante - if not the most important modality in mass screening; 3. new film - screen combinations generally available are capable of producing mammograms of excelent quality with radiation doses down to .1 rad into the body of breast. The risk of malignant changes from such dosage - even when given periodically is negligeable. New equipment, to be available, shortly, will use the new film - screen combinations in an automated manner with must reduce cost in time, filme, personnel and processing - of more than 50%. This would make mass screening more practical. (M.A.) [pt

  12. Mass Spectrometry of Halopyrazolium Salts

    DEFF Research Database (Denmark)

    Larsen, Elfinn; Egsgaard, Helge; Pande, U. C.

    1983-01-01

    Eleven halogen substituted 1-methyl-2-phenylpyrazolium bromides or chlorides were investigated by field desorption, field ionization, and electron impact mass spectrometry. Dealkylation was found to be the predominant thermal decomposition. An exchange between covalent and ionic halogen prior...

  13. Laser sputter neutral mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    King, B V; Clarke, M; Hu, H; Betz, [Newcastle Univ., NSW (Australia). Dept. of Physics

    1994-12-31

    Laser sputter neutral mass spectrometry (LSNMS) is an emerging technique for highly sensitive surface analysis. In this technique a target is bombarded with a pulsed beam of keV ions. The sputtered particles are intercepted by a high intensity pulsed laser beam above the surface and ionised with almost 100% efficiency. The photions may then be mass analysed using a quadrupole or, more commonly, using time of flight (TOF) techniques. In this method photoions are extracted from the ionisation region, accelerated to a known energy E{sub o} and strike a channelplate detector a distance `d` away. The flight time `t` of the photoions is then related to their mass by `d` {radical}m / {radical} 2E{sub o} so measurement of `t` allows mass spectra to be obtained. It is found that LSNMS is an emerging technique of great sensitivity and flexibility, useful for both applied analysis and to investigate basic sputtering processes. 4 refs., 3 figs.

  14. On the hadron mass decomposition

    Science.gov (United States)

    Lorcé, Cédric

    2018-02-01

    We argue that the standard decompositions of the hadron mass overlook pressure effects, and hence should be interpreted with great care. Based on the semiclassical picture, we propose a new decomposition that properly accounts for these pressure effects. Because of Lorentz covariance, we stress that the hadron mass decomposition automatically comes along with a stability constraint, which we discuss for the first time. We show also that if a hadron is seen as made of quarks and gluons, one cannot decompose its mass into more than two contributions without running into trouble with the consistency of the physical interpretation. In particular, the so-called quark mass and trace anomaly contributions appear to be purely conventional. Based on the current phenomenological values, we find that in average quarks exert a repulsive force inside nucleons, balanced exactly by the gluon attractive force.

  15. Mass of the 158Sm

    International Nuclear Information System (INIS)

    Zhao Kui; Guo Jiyu; Lu Xiuqin; Cheng Yehao; Huang Xiaolin; Ma Yong; Li Shuyuan; Ruan Ming; Li Zhichang; Jiang Chenglie

    1997-01-01

    A preliminary result was reported for the experiment to determine the mass of the heavier neutron-rich nucleus 158 Sm using the 160 Gd( 18 O, 20 Ne) two proton transfer reaction in last progress report. The average Q-value of (4.046 +- 0.102) MeV for the 160 Gd( 18 O, 20 Ne) 158 Sm reaction is given. A mass excess for 158 Sm of (-65.738 +- 0.102) MeV was derived. This is the first experimentally measured value of the mass of 158 Sm which is about 450 keV higher than the evaluation value from systematic trends listed in the 1993 atomic mass table. The new prediction shows better agreement with the measured values and a significant improvement over the earlier FRDM (finite-range droplet model) value

  16. Laser sputter neutral mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    King, B.V.; Clarke, M.; Hu, H.; Betz [Newcastle Univ., NSW (Australia). Dept. of Physics

    1993-12-31

    Laser sputter neutral mass spectrometry (LSNMS) is an emerging technique for highly sensitive surface analysis. In this technique a target is bombarded with a pulsed beam of keV ions. The sputtered particles are intercepted by a high intensity pulsed laser beam above the surface and ionised with almost 100% efficiency. The photions may then be mass analysed using a quadrupole or, more commonly, using time of flight (TOF) techniques. In this method photoions are extracted from the ionisation region, accelerated to a known energy E{sub o} and strike a channelplate detector a distance `d` away. The flight time `t` of the photoions is then related to their mass by `d` {radical}m / {radical} 2E{sub o} so measurement of `t` allows mass spectra to be obtained. It is found that LSNMS is an emerging technique of great sensitivity and flexibility, useful for both applied analysis and to investigate basic sputtering processes. 4 refs., 3 figs.

  17. On the hadron mass decomposition

    Energy Technology Data Exchange (ETDEWEB)

    Lorce, Cedric [Universite Paris-Saclay, Centre de Physique Theorique, Ecole Polytechnique, CNRS, Palaiseau (France)

    2018-02-15

    We argue that the standard decompositions of the hadron mass overlook pressure effects, and hence should be interpreted with great care. Based on the semiclassical picture, we propose a new decomposition that properly accounts for these pressure effects. Because of Lorentz covariance, we stress that the hadron mass decomposition automatically comes along with a stability constraint, which we discuss for the first time. We show also that if a hadron is seen as made of quarks and gluons, one cannot decompose its mass into more than two contributions without running into trouble with the consistency of the physical interpretation. In particular, the so-called quark mass and trace anomaly contributions appear to be purely conventional. Based on the current phenomenological values, we find that in average quarks exert a repulsive force inside nucleons, balanced exactly by the gluon attractive force. (orig.)

  18. Ultrasonic prediction of fetal mass

    African Journals Online (AJOL)

    1983-02-19

    Feb 19, 1983 ... Summary. A clinically accurate method for estimating fetal. mass from fetal body parameters is reviewed. The abdominal circumference is first calculated from ... reliable clinical parameter is the impression of uterine volume,.

  19. Food Mass Reduction Trade Study

    Science.gov (United States)

    Perchonok, Michele H.; Stoklosa, Adam M.

    2009-01-01

    Future long duration manned space flights beyond low earth orbit will require the food system to remain safe, acceptable, and nutritious while efficiently balancing appropriate vehicle resources such as mass, volume, power, water, and crewtime. Often, this presents a challenge since maintaining the quality of the food system can result in a higher mass and volume. The Orion vehicle is significantly smaller than the Shuttle vehicle and the International Space Station and the mass and volume available for food is limited. Therefore, the food team has been challenged to reduce the mass of the packaged food from 1.82 kg per person per day to 1.14 kg per person per day. Past work has concentrated on how to reduce the mass of the packaging which contributes to about 15% of the total mass of the packaged food system. Designers have also focused on integrating and optimizing the Orion galley equipment as a system to reduce mass. To date, there has not been a significant effort to determine how to reduce the food itself. The objective of this project is to determine how the mass and volume of the packaged food can be reduced while maintaining caloric and hydration requirements. The following tasks are the key elements to this project: (1) Conduct further analysis of the ISS Standard Menu to determine moisture, protein, carbohydrate, and fat levels. (2) Conduct trade studies to determine how to bring the mass of the food system down. Trade studies may include removing the water of the total food system and/or increasing the fat content. (3) Determine the preferred method for delivery of the new food (e.g. bars, or beverages) and the degree of replacement. (4) Determine whether there are commercially available products that meet the requirements. By the end of this study, an estimate of the mass and volume savings will be provided to the Constellation Program. In addition, if new technologies need to be developed to achieve the mass savings, the technologies, timeline, and

  20. Ion trajectories quadrupole mass filters

    International Nuclear Information System (INIS)

    Ursu, D.; Lupsa, N.; Muntean, F.

    1994-01-01

    The present paper aims at bringing some contributions to the understanding of ion motion in quadrupole mass filters. The theoretical treatment of quadrupole mass filter is intended to be a concise derivation of the important physical relationships using Mathieu functions. A simple iterative method of numerical computation has been used to simulate ion trajectories in an ideal quadrupole field. Finally, some examples of calculation are presented with the aid of computer graphics. (Author) 14 Figs., 1 Tab., 20 Refs

  1. Physics of the neutrino mass

    International Nuclear Information System (INIS)

    Mohapatra, R N

    2004-01-01

    Recent neutrino oscillation experiments have yielded valuable information on the nature of neutrino masses and mixings and qualify as the first evidence for physics beyond the standard model. Even though we are far from a complete understanding of the new physics implied by them, there are many useful hints. As the next precision era in neutrino physics is about to be launched, we review the physics of neutrino mass: what we have learned and what we are going to learn

  2. Mass extinctions and supernova explosions

    OpenAIRE

    Korschinek, Gunther

    2016-01-01

    A nearby supernova (SN) explosion could have negatively influenced life on Earth, maybe even been responsible for mass extinctions. Mass extinction poses a significant extinction of numerous species on Earth, as recorded in the paleontologic, paleoclimatic, and geological record of our planet. Depending on the distance between the Sun and the SN, different types of threats have to be considered, such as ozone depletion on Earth, causing increased exposure to the Sun's ultraviolet radiation, o...

  3. Glueball masses in quantum chromodynamics

    International Nuclear Information System (INIS)

    Luo Xiangqian; Zhongshan Univ., Guangzhou, GD; Zhongshan Univ., Guangzhou; Chen Qizhou; Zhongshan Univ., Guangzhou, GD; Zhongshan Univ., Guangzhou; Guo Shuohong; Zhongshan Univ., Guangzhou, GD; Zhongshan Univ., Guangzhou; Fang Xiyan; Zhongshan Univ., Guangzhou, GD; Zhongshan Univ., Guangzhou; Liu Jinming; Zhongshan Univ., Guangzhou, GD; Zhongshan Univ., Guangzhou

    1996-01-01

    We review the recent glueball mass calculations using an efficient method for solving the Schroedinger equation order by order with a scheme preserving the continuum limit. The reliability of the method is further supported by new accurate results for (1+1)-dimensional σ models and (2+1)-dimensional non-abelian models. We present first and encouraging data for the glueball masses in 3+1 dimensional QCD. (orig.)

  4. Mass storage for microprocessor farms

    International Nuclear Information System (INIS)

    Areti, H.

    1990-01-01

    Experiments in high energy physics require high density and high speed mass storage. Mass storage is needed for data logging during the online data acquisition, data retrieval and storage during the event reconstruction and data manipulation during the physics analysis. This paper examines the storage and speed requirements at the first two stages of the experiments and suggests a possible starting point to deal with the problem. 3 refs., 3 figs

  5. Neutrino Mass and Flavour Models

    International Nuclear Information System (INIS)

    King, Stephen F.

    2010-01-01

    We survey some of the recent promising developments in the search for the theory behind neutrino mass and tri-bimaximal mixing, and indeed all fermion masses and mixing. We focus in particular on models with discrete family symmetry and unification, and show how such models can also solve the SUSY flavour and CP problems. We also discuss the theoretical implications of the measurement of a non-zero reactor angle, as hinted at by recent experimental measurements.

  6. The Sixth Great Mass Extinction

    Science.gov (United States)

    Wagler, Ron

    2012-01-01

    Five past great mass extinctions have occurred during Earth's history. Humanity is currently in the midst of a sixth, human-induced great mass extinction of plant and animal life (e.g., Alroy 2008; Jackson 2008; Lewis 2006; McDaniel and Borton 2002; Rockstrom et al. 2009; Rohr et al. 2008; Steffen, Crutzen, and McNeill 2007; Thomas et al. 2004;…

  7. Masses of Nix and Hydra

    Science.gov (United States)

    Tholen, David J.; Buie, M. W.; Grundy, W.

    2007-05-01

    Two new, small satellites of Pluto were discovered in 2005 using deep images from the Hubble Space Telescope. The IAU has approved the name Hydra for the outermost satellite and the name Nix for the one orbiting at an intermediate distance between Charon and Hydra. We used the two discovery observations of Nix and Hydra from 2005, the two confirmation observations from 2006, and the twelve prediscovery observations from 2001 and 2002, as well as available observations of Charon, to perform a four-body orbit solution for the Pluto system. Mutual perturbations have placed constraints on the masses of each member of the system. Previous work placed useful limits on the masses of Pluto and Charon, as well as their densities, given the known sizes of the bodies based on stellar occultation and mutual event observations, therefore our new work is aimed at placing constraints on the masses of Nix and Hydra. The best-fit GM values for Nix and Hydra are 0.040 and 0.021 km3 sec-2. The uncertainty in the GM of Hydra is large enough to allow for a negligible mass. At the one-sigma level, we can rule out masses near the upper limit of what is physically reasonable (correpsonding to a combination of low albedos and high densities) for both satellites, and in the case of Nix, we can also rule out a mass near the lower limit (corresponding to a high albedo and low density). We have determined empirically that the rate of precession of the line of apsides of Charon's slightly eccentric orbit is proportional to the mass of Nix and Hydra. New HST observations of the satellites are scheduled, which should improve the orbit solution and reduce the uncertainties in the masses. Ultimately, these results will place constraints on models for the formation of the system.

  8. Pulsation, Mass Loss and the Upper Mass Limit

    Science.gov (United States)

    Klapp, J.; Corona-Galindo, M. G.

    1990-11-01

    RESUMEN. La existencia de estrellas con masas en exceso de 100 M0 ha sido cuestionada por mucho tiempo. Lfmites superiores para la masa de 100 M0 han sido obtenidos de teorfas de pulsaci6n y formaci6n estelar. En este trabajo nosotros primero investigamos la estabilidad radial de estrellas masivas utilizando la aproximaci6n clasica cuasiadiabatica de Ledoux, la aproximaci6n cuasiadiabatica de Castor y un calculo completamente no-adiabatico. Hemos encontrado que los tres metodos de calculo dan resultados similares siempre y cuando una pequefia regi6n de las capas externas de la estrella sea despreciada para la aproximaci6n clasica. La masa crftica para estabilidad de estrellas masivas ha sido encontrada en acuerdo a trabajos anteriores. Explicamos Ia discrepancia entre este y trabajos anteriores por uno de los autores. Discunmos calculos no-lineales y perdida de masa con respecto a) lfmite superior de masa. The existence of stars with masses in excess of 100 M0 has been questioned for a very long time. Upper mass limits of 100 Me have been obtained from pulsation and star formation theories. In this work we first investigate the radial stability of massive stars using the classical Ledoux's quasiadiabatic approximation. the Castor quasiadiabatic approximation and a fully nonadiabatic calculation. We have found that the three methods of calculation give similar results provided that a small region in outer layers of the star be neglected for the classical approximation. The critical mass for stability of massive stars is found to be in agreement with previous work. We explain the reason for the discrepancy between this and previous work by one of the authors. We discuss non-linear calculations and mass loss with regard to the upper mass limit. Key words: STARS-MASS FUNCTION - STARS-MASS LOSS - STARS-PULSATION

  9. Stellar Initial Mass Function: Trends With Galaxy Mass And Radius

    Science.gov (United States)

    Parikh, Taniya

    2017-06-01

    There is currently no consensus about the exact shape and, in particular, the universality of the stellar initial mass function (IMF). For massive galaxies, it has been found that near-infrared (NIR) absorption features, which are sensitive to the ratio of dwarf to giant stars, deviate from a Milky Way-like IMF; their modelling seems to require a larger fraction of low mass stars. There are now increasing results looking at whether the IMF varies not only with galaxy mass, but also radially within galaxies. The SDSS-IV/MaNGA integral-field survey will provide spatially resolved spectroscopy for 10,000 galaxies at R 2000 from 360-1000nm. Spectra of early-type galaxies were stacked to achieve high S/N which is particularly important for features in the NIR. Trends with galaxy radius and mass were compared to stellar population models for a range of absorption features in order to separate degeneracies due to changes in stellar population parameters, such as age, metallicity and element abundances, with potential changes in the IMF. Results for 611 galaxies show that we do not require an IMF steeper than Kroupa as a function of galaxy mass or radius based on the NaI index. The Wing-Ford band hints towards a steeper IMF at large radii however we do not have reliable measurements for the most massive galaxies.

  10. MASS-RADIUS RELATIONSHIPS FOR VERY LOW MASS GASEOUS PLANETS

    International Nuclear Information System (INIS)

    Batygin, Konstantin; Stevenson, David J.

    2013-01-01

    Recently, the Kepler spacecraft has detected a sizable aggregate of objects, characterized by giant-planet-like radii and modest levels of stellar irradiation. With the exception of a handful of objects, the physical nature, and specifically the average densities, of these bodies remain unknown. Here, we propose that the detected giant planet radii may partially belong to planets somewhat less massive than Uranus and Neptune. Accordingly, in this work, we seek to identify a physically sound upper limit to planetary radii at low masses and moderate equilibrium temperatures. As a guiding example, we analyze the interior structure of the Neptune-mass planet Kepler-30d and show that it is acutely deficient in heavy elements, especially compared with its solar system counterparts. Subsequently, we perform numerical simulations of planetary thermal evolution and in agreement with previous studies, show that generally, 10-20 M ⊕ , multi-billion year old planets, composed of high density cores and extended H/He envelopes can have radii that firmly reside in the giant planet range. We subject our results to stability criteria based on extreme ultraviolet radiation, as well as Roche-lobe overflow driven mass-loss and construct mass-radius relationships for the considered objects. We conclude by discussing observational avenues that may be used to confirm or repudiate the existence of putative low mass, gas-dominated planets.

  11. ACTOMP - AUTOCAD TO MASS PROPERTIES

    Science.gov (United States)

    Jones, A.

    1994-01-01

    AutoCAD to Mass Properties was developed to facilitate quick mass properties calculations of structures having many simple elements in a complex configuration such as trusses or metal sheet containers. Calculating the mass properties of structures of this type can be a tedious and repetitive process, but ACTOMP helps automate the calculations. The structure can be modelled in AutoCAD or a compatible CAD system in a matter of minutes using the 3-Dimensional elements. This model provides all the geometric data necessary to make a mass properties calculation of the structure. ACTOMP reads the geometric data of a drawing from the Drawing Interchange File (DXF) used in AutoCAD. The geometric entities recognized by ACTOMP include POINTs, 3DLINEs, and 3DFACEs. ACTOMP requests mass, linear density, or area density of the elements for each layer, sums all the elements and calculates the total mass, center of mass (CM) and the mass moments of inertia (MOI). AutoCAD utilizes layers to define separate drawing planes. ACTOMP uses layers to differentiate between multiple types of similar elements. For example if a structure is made of various types of beams, modeled as 3DLINEs, each with a different linear density, the beams can be grouped by linear density and each group placed on a separate layer. The program will request the linear density of 3DLINEs for each new layer it finds as it processes the drawing information. The same is true with POINTs and 3DFACEs. By using layers this way a very complex model can be created. POINTs are used for point masses such as bolts, small machine parts, or small electronic boxes. 3DLINEs are used for beams, bars, rods, cables, and other similarly slender elements. 3DFACEs are used for planar elements. 3DFACEs may be created as 3 or 4 Point faces. Some examples of elements that might be modelled using 3DFACEs are plates, sheet metal, fabric, boxes, large diameter hollow cylinders and evenly distributed masses. ACTOMP was written in Microsoft

  12. Methods for recalibration of mass spectrometry data

    Science.gov (United States)

    Tolmachev, Aleksey V [Richland, WA; Smith, Richard D [Richland, WA

    2009-03-03

    Disclosed are methods for recalibrating mass spectrometry data that provide improvement in both mass accuracy and precision by adjusting for experimental variance in parameters that have a substantial impact on mass measurement accuracy. Optimal coefficients are determined using correlated pairs of mass values compiled by matching sets of measured and putative mass values that minimize overall effective mass error and mass error spread. Coefficients are subsequently used to correct mass values for peaks detected in the measured dataset, providing recalibration thereof. Sub-ppm mass measurement accuracy has been demonstrated on a complex fungal proteome after recalibration, providing improved confidence for peptide identifications.

  13. Mass shooting and mass media : does media coverage of mass shootings inspire copycat crimes?

    OpenAIRE

    Mesoudi, A.

    2013-01-01

    In December 2012, twenty elementary school children and six adult staff members were shot and killed by a single individual at a school in Connecticut. Although this horrific event was met with widespread shock, Americans are sadly all too familiar with such mass shootings. From Columbine in 1999, to Virginia Tech in 2007, to the Colorado cinema shootings earlier in 2012, mass shootings seem to occur with alarming regularity. And although they appear to afflict the United States more than mos...

  14. Top-quark mass from the diphoton mass spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Kawabata, Sayaka [Seoul National University of Science and Technology, Institute of Convergence Fundamental Studies, Seoul (Korea, Republic of); Yokoya, Hiroshi [Quantum Universe Center, KIAS, Seoul (Korea, Republic of)

    2017-05-15

    We calculate the gg → γγ amplitude by including the t anti t bound-state effects near their mass threshold. In terms of the non-relativistic expansion of the amplitude, the LO contribution is an energy-independent term in the one-loop amplitude. We include the NLO contribution described by the non-relativistic Green function and part of the NNLO contribution. Despite a missing NLO piece which can be accomplished with the two-loop-level amplitude via massive quarks, the shape of the diphoton mass spectrum is predicted with a good accuracy. Thanks to the simple and clean nature of the observable, its experimental measurement can be a direct method to determine the short-distance mass of the top quark at hadron colliders. (orig.)

  15. STELLAR MASS DEPENDENT DISK DISPERSAL

    International Nuclear Information System (INIS)

    Kennedy, Grant M.; Kenyon, Scott J.

    2009-01-01

    We use published optical spectral and infrared (IR) excess data from nine young clusters and associations to study the stellar mass dependent dispersal of circumstellar disks. All clusters older than ∼3 Myr show a decrease in disk fraction with increasing stellar mass for solar to higher mass stars. This result is significant at about the 1σ level in each cluster. For the complete set of clusters we reject the null hypothesis-that solar and intermediate-mass stars lose their disks at the same rate-with 95%-99.9% confidence. To interpret this behavior, we investigate the impact of grain growth, binary companions, and photoevaporation on the evolution of disk signatures. Changes in grain growth timescales at fixed disk temperature may explain why early-type stars with IR excesses appear to evolve faster than their later-type counterparts. Little evidence that binary companions affect disk evolution suggests that photoevaporation is the more likely mechanism for disk dispersal. A simple photoevaporation model provides a good fit to the observed disk fractions for solar and intermediate-mass stars. Although the current mass-dependent disk dispersal signal is not strong, larger and more complete samples of clusters with ages of 3-5 Myr can improve the significance and provide better tests of theoretical models. In addition, the orbits of extra-solar planets can constrain models of disk dispersal and migration. We suggest that the signature of stellar mass dependent disk dispersal due to photoevaporation may be present in the orbits of observed extra-solar planets. Planets orbiting hosts more massive than ∼1.6 M sun may have larger orbits because the disks in which they formed were dispersed before they could migrate.

  16. Mass Determination of Entire Amyloid Fibrils by Using Mass Spectrometry.

    Science.gov (United States)

    Doussineau, Tristan; Mathevon, Carole; Altamura, Lucie; Vendrely, Charlotte; Dugourd, Philippe; Forge, Vincent; Antoine, Rodolphe

    2016-02-12

    Amyloid fibrils are self-assembled protein structures with important roles in biology (either pathogenic or physiological), and are attracting increasing interest in nanotechnology. However, because of their high aspect ratio and the presence of some polymorphism, that is, the possibility to adopt various structures, their characterization is challenging and basic information such as their mass is unknown. Here we show that charge-detection mass spectrometry, recently developed for large self-assembled systems such as viruses, provides such information in a straightforward manner. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Light baryon masses with dynamical twisted mass fermions

    Energy Technology Data Exchange (ETDEWEB)

    Alexandrou, C. [Cyprus Univ., Nicosia (Cyprus). Dept. of Physics; Baron, R. [CEA-Saclay, IRFU/Service de Physique Nucleaire, Gif-sur-Yvette (France); Blossier, B. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (DE). John von Neumann-Inst. fuer Computing NIC] (and others)

    2008-03-15

    We present results on the mass of the nucleon and the {delta} using two dynamical degenerate twisted mass quarks. The evaluation is performed at four quark masses corresponding to a pion mass in the range of about 300-600 MeV on lattices of 2.1-2.7 fm. We check for cut-off effects by evaluating these baryon masses on lattices of spatial size 2.1 fm at {beta}=3.9 and {beta}=4.05 and on a lattice of 2.4 fm at {beta}=3.8. The values we find are compatible within our statistical errors. Lattice results are extrapolated to the physical limit using continuum chiral perturbation theory. Performing a combined fit to our lattice data at {beta}=3.9 and {beta}=4.05 we find a nucleon mass of 964{+-}28(stat.){+-}8(syst.) MeV where we used the lattice spacings determined from the pion decay constant to convert to physical units. The systematic error due to the chiral extrapolation is estimated by comparing results obtained at O(p{sup 3}) and O(p{sup 4}) heavy baryon chiral perturbation theory. The nucleon mass at the physical point provides an independent determination of the lattice spacing. Using heavy baryon chiral perturbation theory at O(p{sup 3}) we find a{sub {beta}}{sub =3.9}=0.0890{+-}0.0039(stat.){+-}0.0014(syst.) fm, and a{sub {beta}}{sub =4.05}=0.0691{+-}0.0034(stat.){+-}0.0010(syst.) fm, in good agreement with the values determined from the pion decay constant. Using results from our two smaller lattices spacings at constant r0m we estimate the continuum limit and check consistency with results from the coarser lattice. Results at the continuum limit are chirally extrapolated to the physical point. Isospin violating lattice artifacts in the {delta}-system are found to be compatible with zero for the values of the lattice spacings used in this work. Performing a combined fit to our lattice data at {beta}=3.9 and {beta}=4.05 we find for the masses of the {delta}{sup ++,-} and {delta}{sup +,0} 1316{+-}60(stat.) MeV and 1330{+-}74(stat.) MeV respectively. We confirm

  18. Light baryon masses with dynamical twisted mass fermions

    International Nuclear Information System (INIS)

    Alexandrou, C.; Blossier, B.

    2008-03-01

    We present results on the mass of the nucleon and the Δ using two dynamical degenerate twisted mass quarks. The evaluation is performed at four quark masses corresponding to a pion mass in the range of about 300-600 MeV on lattices of 2.1-2.7 fm. We check for cut-off effects by evaluating these baryon masses on lattices of spatial size 2.1 fm at β=3.9 and β=4.05 and on a lattice of 2.4 fm at β=3.8. The values we find are compatible within our statistical errors. Lattice results are extrapolated to the physical limit using continuum chiral perturbation theory. Performing a combined fit to our lattice data at β=3.9 and β=4.05 we find a nucleon mass of 964±28(stat.)±8(syst.) MeV where we used the lattice spacings determined from the pion decay constant to convert to physical units. The systematic error due to the chiral extrapolation is estimated by comparing results obtained at O(p 3 ) and O(p 4 ) heavy baryon chiral perturbation theory. The nucleon mass at the physical point provides an independent determination of the lattice spacing. Using heavy baryon chiral perturbation theory at O(p 3 ) we find a β=3.9 =0.0890±0.0039(stat.)±0.0014(syst.) fm, and a β=4.05 =0.0691±0.0034(stat.)±0.0010(syst.) fm, in good agreement with the values determined from the pion decay constant. Using results from our two smaller lattices spacings at constant r0m we estimate the continuum limit and check consistency with results from the coarser lattice. Results at the continuum limit are chirally extrapolated to the physical point. Isospin violating lattice artifacts in the Δ-system are found to be compatible with zero for the values of the lattice spacings used in this work. Performing a combined fit to our lattice data at β=3.9 and β=4.05 we find for the masses of the Δ ++,- and Δ +,0 1316±60(stat.) MeV and 1330±74(stat.) MeV respectively. We confirm that in the continuum limit they are also degenerate. (orig.)

  19. Light baryon masses with dynamical twisted mass fermions

    International Nuclear Information System (INIS)

    Alexandrou, C.; Korzec, T.; Koutsou, G.; Baron, R.; Guichon, P.; Blossier, B.; Herdoiza, G.; Jansen, K.; Brinet, M.; Carbonell, J.; Drach, V.; Dimopoulos, P.; Frezzotti, R.; Farchioni, F.; Liu, Z.; Pene, O.; Michael, C.; Shindler, A.; Urbach, C.; Wenger, U.

    2008-01-01

    We present results on the mass of the nucleon and the Δ using two dynamical degenerate twisted mass quarks and the tree-level Symanzik improved gauge action. The evaluation is performed at four quark masses corresponding to a pion mass in the range of about 300-600 MeV on lattices of 2.1-2.7 fm at three lattice spacings less than 0.1 fm. We check for cutoff effects by evaluating these baryon masses on lattices of spatial size 2.1 fm at β=3.9 and β=4.05 and on a lattice of 2.4 fm at β=3.8. The values we find are compatible within our statistical errors. Lattice results are extrapolated to the physical limit using continuum chiral perturbation theory. Performing a combined fit to our lattice data at β=3.9 and β=4.05 we find a nucleon mass of 963±12(stat)±8(syst) MeV where we used the lattice spacings determined from the pion decay constant to convert to physical units. The systematic error due to the chiral extrapolation is estimated by comparing results obtained at O(p 3 ) and O(p 4 ) heavy baryon chiral perturbation theory. The nucleon mass at the physical point provides an independent determination of the lattice spacing. Using heavy baryon chiral perturbation theory at O(p 3 ) we find a β=3.9 =0.0889±0.0012(stat)±0.0014(syst) fm, and a β=4.05 =0.0691±0.0010(stat)±0.0010(syst) fm, in good agreement with the values determined from the pion decay constant. Using results from our two smaller lattices spacings at constant r 0 m π we estimate the continuum limit and check consistency with results from the coarser lattice. Results at the continuum limit are chirally extrapolated to the physical point. Isospin violating lattice artifacts in the Δ-system are found to be compatible with zero for the values of the lattice spacings used in this work. Performing a combined fit to our lattice data at β=3.9 and β=4.05 we find for the masses of the Δ ++,- and Δ +,0 1315±24(stat) MeV and 1329±30(stat) MeV, respectively. We confirm that in the continuum limit

  20. Simultaneous mass detection for direct inlet mass spectrometry

    International Nuclear Information System (INIS)

    Gordon, R.L.

    1979-05-01

    The evolution of analytical techniques for application in trace analysis has led to interest in practical methods for real-time monitoring. Direct inlet mass spectrometry (DIMS) has been the subject of considerable activity in recent years. A DIMS instrument is described which consists of an inlet system designed to permit particles entrained in the inlet air stream to strike a hot, oxidized rhenium filament which serves as a surface ionization source. A mass analyzer and detection system then permits identification of the elemental composition of particulates which strike the filament

  1. Mass psychogenic illness after vaccination.

    Science.gov (United States)

    Clements, C John

    2003-01-01

    When vaccines are administered to groups, the physical reactions of the recipients may be similar, causing a form of mass reaction, the mechanism for which is the same as that for mass reactions from other causes. These phenomena have been categorised as mass psychogenic illness (MPI), and have been defined as the collective occurrence of a constellation of symptoms suggestive of organic illness but without an identified cause in a group of people with shared beliefs about the cause of the symptom(s). A review of the literature shows that such outbreaks have been reported in differing cultural and environmental settings including developing and industrialised countries, in the work place, on public transport, in schools, and the military. The perceived threats have been against agents such as food poisoning, fire and toxic gases. Whatever the place or perceived threat, the response seems to be similar. The symptoms generally included headache, dizziness, weakness, and loss of consciousness. Once under way, MPIs are not easy to stop. Incidents reported in the literature show that they can quickly gather momentum and can be amplified by the press who disseminate information rapidly, escalating the events. Management of such mass events can be extremely difficult. Should the public health official in charge continue to try and determine the cause, or should this person call off the entire investigation? It is suggested here that once vaccines are identified as a probable cause of the phenomenon, a dismissive approach may actually be harmful. Unless the spokesperson has already earned a high level of trust, the public are not likely to be convinced easily that nothing was wrong with the vaccine until it has been tested. An increased awareness of MPIs on the part of organisers of future mass vaccination campaigns seems appropriate. Immunisation managers should be aware that mass immunisation campaigns could generate such mass reactions. It is therefore essential that

  2. Photon and graviton mass limits

    International Nuclear Information System (INIS)

    Goldhaber, Alfred Scharff; Nieto, Michael Martin

    2010-01-01

    Efforts to place limits on deviations from canonical formulations of electromagnetism and gravity have probed length scales increasing dramatically over time. Historically, these studies have passed through three stages: (1) testing the power in the inverse-square laws of Newton and Coulomb, (2) seeking a nonzero value for the rest mass of photon or graviton, and (3) considering more degrees of freedom, allowing mass while preserving explicit gauge or general-coordinate invariance. Since the previous review the lower limit on the photon Compton wavelength has improved by four orders of magnitude, to about one astronomical unit, and rapid current progress in astronomy makes further advance likely. For gravity there have been vigorous debates about even the concept of graviton rest mass. Meanwhile there are striking observations of astronomical motions that do not fit Einstein gravity with visible sources. ''Cold dark matter'' (slow, invisible classical particles) fits well at large scales. ''Modified Newtonian dynamics'' provides the best phenomenology at galactic scales. Satisfying this phenomenology is a requirement if dark matter, perhaps as invisible classical fields, could be correct here too. ''Dark energy''might be explained by a graviton-mass-like effect, with associated Compton wavelength comparable to the radius of the visible universe. Significant mass limits are summarized in a table.

  3. Imaging in cardiac mass lesions

    International Nuclear Information System (INIS)

    Mundinger, A.; Gruber, H.P.; Dinkel, E.; Geibel, A.; Beck, A.; Wimmer, B.; Schlosser, V.

    1992-01-01

    In 26 patients with cardiac mass lesions confirmed by surgery, diagnostic imaging was performed preoperatively by means of two-dimensional echocardiography (26 patients), angiography (12 patients), correlative computed tomography (CT, 8 patients), and magnetic resonance imaging (MRI, 3 patients). Two-dimensional echocardiography correctly identified the cardiac masses in all patients. Angiography missed two of 12 cardiac masses; CT missed one of eight. MRI identified three of three cardiac masses. Although the sensitivity of two-dimensional echocardiography was high (100%), all methods lacked specificity. None of the methods allowed differentiation between myxoma (n=13) and thrombus (n=7). Malignancy of the lesions was successfully predicted by noninvasive imaging methods in all six patients. However, CT and MRI provided additional information concerning cardiac mural infiltration, pericardial involvement, and extracardiac tumor extension, and should be integrated within a preoperative imaging strategy. Thus two-dimensional echocardiography is the method of choice for primary assessment of patients with suspected cardiac masses. Further preoperative imaging by CT or MRI can be limited to patients with malignancies suspected on the grounds of pericardial effusion or other clinical results. (author)

  4. Photon and graviton mass limits

    Science.gov (United States)

    Goldhaber, Alfred Scharff; Nieto, Michael Martin

    2010-01-01

    Efforts to place limits on deviations from canonical formulations of electromagnetism and gravity have probed length scales increasing dramatically over time. Historically, these studies have passed through three stages: (1) testing the power in the inverse-square laws of Newton and Coulomb, (2) seeking a nonzero value for the rest mass of photon or graviton, and (3) considering more degrees of freedom, allowing mass while preserving explicit gauge or general-coordinate invariance. Since the previous review the lower limit on the photon Compton wavelength has improved by four orders of magnitude, to about one astronomical unit, and rapid current progress in astronomy makes further advance likely. For gravity there have been vigorous debates about even the concept of graviton rest mass. Meanwhile there are striking observations of astronomical motions that do not fit Einstein gravity with visible sources. “Cold dark matter” (slow, invisible classical particles) fits well at large scales. “Modified Newtonian dynamics” provides the best phenomenology at galactic scales. Satisfying this phenomenology is a requirement if dark matter, perhaps as invisible classical fields, could be correct here too. “Dark energy” might be explained by a graviton-mass-like effect, with associated Compton wavelength comparable to the radius of the visible universe. Significant mass limits are summarized in a table.

  5. On the relativistic mass conception

    International Nuclear Information System (INIS)

    Kard, P.

    1979-01-01

    Mass of light is generally substantiated with the use of the Einstein known mental experiment with a cylinder displacing under the pressure of light flare emitted at one of its ends and absorbed at the other. This experiment is not rigorous however and involves a logical circle. Another method is presented to substantiate mass of light. The initial conditions are as follows: the law of momentum conservation, evailability of light pulse, momentum parallelism to a velocity, and the general ralativistic formula of velocity transformation. A consideration is given to directed emission of light flux by a body in two internal systems, viz. in the system of initial rest of the body and in the system moving relatively to it with an arbitrary velocity. The law of momentum conservation being used in both systems, as well as formulae for velocity transformation, the formulae are obtained which show that light has mass. The general law of mass conservation is derived as a consequence of the formulae for mass and momentum transformations

  6. Psychosocial considerations for mass decontamination

    International Nuclear Information System (INIS)

    Lemyre, L.; Johnson, C.; Corneil, W.

    2010-01-01

    Mass exposure to explosions, infectious agents, food-borne illnesses, chemicals or radiological materials may require mass decontamination that have critical psychosocial implications for the public and for both traditional and non-traditional responders in terms of impact and of response. Five main issues are common to mass decontamination events: (i) perception, (ii) somatisation, (iii) media role and communication, (iv) information sharing, (v) behavioural guidance and (vi) organisational issues. Empirical evidence is drawn from a number of cases, including Chernobyl; Goiania, Brazil; the sarin gas attack in Tokyo; the anthrax attacks in the USA; Three Mile Island; and by features of the 2003 severe acute respiratory syndrome pandemic. In this paper, a common platform for mass casualty management is explored and suggestions for mass interventions are proposed across the complete event timeline, from pre-event threat and warning stages through to the impact and reconstruction phases. Implication for responders, health care and emergency infrastructure, public behaviour, screening processes, risk communication and media management are described. (authors)

  7. Photon and graviton mass limits

    Energy Technology Data Exchange (ETDEWEB)

    Nieto, Michael [Los Alamos National Laboratory; Goldhaber Scharff, Alfred [SUNY

    2008-01-01

    We review past and current studies of possible long-distance, low-frequency deviations from Maxwell electrodynamics and Einstein gravity. Both have passed through three phases: (1) Testing the inverse-square laws of Newton and Coulomb, (2) Seeking a nonzero value for the rest mass of photon or graviton, and (3) Considering more degrees of freedom, allowing mass while preserving gauge or general-coordinate invariance. For electrodynamics there continues to be no sign of any deviation. Since our previous review the lower limit on the photon Compton wavelength (associated with weakening of electromagnetic fields in vacuum over large distance scale) has improved by four orders of magnitude, to about one astronomical unit. Rapid current progress in astronomical observations makes it likely that there will be further advances. These ultimately could yield a bound exceeding galactic dimensions, as has long been contemplated. Meanwhile, for gravity there have been strong arguments about even the concept of a graviton rest mass. At the same time there are striking observations, commonly labeled 'dark matter' and 'dark energy' that some argue imply modified gravity. This makes the questions for gravity much more interesting. For dark matter, which involves increased attraction at large distances, any explanation by modified gravity would be qualitatively different from graviton mass. Because dark energy is associated with reduced attraction at large distances, it might be explained by a graviton-mass-like effect.

  8. Rare Cause of Dysphagy: Giant Polypoid Esophageal Well-Differentiated Liposarcoma

    Directory of Open Access Journals (Sweden)

    Ladislav Mica

    2007-06-01

    Full Text Available Liposarcoma represents one of the most frequent (10–20% malignant mesenchymal tumors in the adult, affecting mostly the soft tissue of extremities, the trunk or the retroperitoneum. This tumor type occurs exceptionally rarely in the gastrointestinal tract with only few cases described in the literature. In this case we present a 73-year-old male patient who was admitted due to loss of weight, anorexia and postprandial emesis with dysphagy. Gastrographin esophagography failed to make precise diagnostics. CT scan of the upper gastrointestinal tract revealed a large esophageal tumor filling out the whole length of the esophagus. The tumor was removed by parasternocleidomastoidal approach with a stapler. Histopathological examination revealed a well-differentiated liposarcoma (grade I. Well-differentiated liposarcomas are characterised by amplified material of the 12q13–15 chromosomal region, present in the form of giant or ring chromosomes and leading to the overexpression of MDM2 and CDK4 genes. MDM2 and CDK4 proteins can be detected immunhistochemically, which was the case in the reported tumor. Overexpression of these proteins leads to suppression of tumor suppressor genes, leading to increased cell survival.

  9. Long-term outcomes of fertility-sparing treatment of atypical polypoid adenomyoma with medroxyprogesterone acetate.

    Science.gov (United States)

    Nomura, Hidetaka; Sugiyama, Yuko; Tanigawa, Terumi; Matoda, Maki; Kanao, Hiroyuki; Kondo, Eiji; Takeshima, Nobuhiro

    2016-01-01

    Our objective was to analyze the long-term oncologic outcomes of fertility-preserving hormonal treatment with medroxyprogesterone acetate (MPA) in patients with APA. In a retrospective chart review, we identified patients with APA who were treated with MPA for fertility preservation at our hospital between 2001 and 2011. Eighteen patients with histologically diagnosed APA were identified. Clinical data including treatment, obstetrical, and oncologic outcomes were recorded. The mean observation period was 77.6 months (median 73.5, range 22-142), and the mean age was 33.6 years. Four patients also developed well-differentiated endometrial carcinoma. After the treatment, 14 patients (77.8 %) achieved either a complete response or partial response. Eight patients experienced recurrence, while four experienced persistent disease. Ten patients (55.6 %) eventually underwent hysterectomy. The median time to hysterectomy was 40.3 months (range 24-68). Nine patients progressed to endometrial cancer, and one experienced persistent APA. Among younger patients (years of age), four out of five patients who were married could have children. Seven patients (38.9 %) showed no evidence of the disease during the observation period (median 60 months, range 22-117 months). No one died because of the disease during the observation period. MPA yields a high response rate in APA, and if only younger patients are considered, a favorable pregnancy rate can be obtained. However, because recurrence rate is high, long-term follow-up under supervision of a trained gynecologic oncologist is required. To confirm MPA's utility, multi-center collaboration would be warranted.

  10. Polypoid endometriosis mimicking invasive cancer in an obese, postmenopausal tamoxifen user

    Directory of Open Access Journals (Sweden)

    William T. Jaegle

    2017-11-01

    Précis: Endometriosis is a benign estrogen dependent condition rarely problematic in a postmenopausal patient. Tamoxifen use in the setting of an obese patient may contribute to a proliferation of pre-existing endometriosis which resembles an aggressive late-stage gynecological malignancy.

  11. Software for mass spectrometer control

    International Nuclear Information System (INIS)

    Curuia, Marian; Culcer, Mihai; Anghel, Mihai; Iliescu, Mariana; Trancota, Dan; Kaucsar, Martin; Oprea, Cristiana

    2004-01-01

    The paper describes a software application for the MAT 250 mass spectrometer control, which was refurbished. The spectrometer was bring-up-to-date using a hardware structure on its support where the software application for mass spectrometer control was developed . The software application is composed of dedicated modules that perform given operations. The instructions that these modules have to perform are generated by a principal module. This module makes possible the change of information between the modules that compose the software application. The use of a modal structure is useful for adding new functions in the future. The developed application in our institute made possible the transformation of the mass spectrometer MAT 250 into a device endowed with other new generation tools. (authors)

  12. Gauge Trimming of Neutrino Masses

    International Nuclear Information System (INIS)

    Chen, Mu-Chun; de Gouvea, Andre; Dobrescu, Bogdan A.

    2006-01-01

    We show that under a new U(1) gauge symmetry, which is non-anomalous in the presence of one ''right-handed neutrino'' per generation and consistent with the standard model Yukawa couplings, the most general fermion charges are determined in terms of four rational parameters. This generalization of the B-L symmetry with generation-dependent lepton charges leads to neutrino masses induced by operators of high dimensionality. Neutrino masses are thus naturally small without invoking physics at energies above the TeV scale, whether neutrinos are Majorana or Dirac fermions. This ''Leptocratic'' Model predicts the existence of light quasi-sterile neutrinos with consequences for cosmology, and implies that collider experiments may reveal the origin of neutrino masses

  13. Symposium on accelerator mass spectrometry

    International Nuclear Information System (INIS)

    1981-01-01

    The area of accelerator mass spectrometry has expanded considerably over the past few years and established itself as an independent and interdisciplinary research field. Three years have passed since the first meeting was held at Rochester. A Symposium on Accelerator Mass Spectrometry was held at Argonne on May 11-13, 1981. In attendance were 96 scientists of whom 26 were from outside the United States. The present proceedings document the program and excitement of the field. Papers are arranged according to the original program. A few papers not presented at the meeting have been added to complete the information on the status of accelerator mass spectrometry. Individual papers were prepared separately for the data base

  14. Symposium on accelerator mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-01-01

    The area of accelerator mass spectrometry has expanded considerably over the past few years and established itself as an independent and interdisciplinary research field. Three years have passed since the first meeting was held at Rochester. A Symposium on Accelerator Mass Spectrometry was held at Argonne on May 11-13, 1981. In attendance were 96 scientists of whom 26 were from outside the United States. The present proceedings document the program and excitement of the field. Papers are arranged according to the original program. A few papers not presented at the meeting have been added to complete the information on the status of accelerator mass spectrometry. Individual papers were prepared separately for the data base.

  15. Neutrino masses and family replication

    International Nuclear Information System (INIS)

    Hung, P.Q.

    1999-01-01

    The issue of whether or not there is any link between the smallness of the neutrino mass (if present) and the odd or even nature of the number of families is investigated. It is found that, by assuming the existence of right-handed neutrinos (which would imply that neutrinos will have a mass) and a new chiral SU(2) gauge theory, a constraint on the nature of the number of families can be obtained. In addition, a model, based on that extra SU(2), is constructed where it is plausible to have one 'very heavy' fourth neutrino and three almost degenerate light neutrinos whose masses are all of the Dirac type. copyright 1999 The American Physical Society

  16. Coronal Mass Ejections An Introduction

    CERN Document Server

    Howard, Timothy

    2011-01-01

    In times of growing technological sophistication and of our dependence on electronic technology, we are all affected by space weather. In its most extreme form, space weather can disrupt communications, damage and destroy spacecraft and power stations, and increase radiation exposure to astronauts and airline passengers. Major space weather events, called geomagnetic storms, are large disruptions in the Earth’s magnetic field brought about by the arrival of enormous magnetized plasma clouds from the Sun. Coronal mass ejections (CMEs) contain billions of tons of plasma and hurtle through space at speeds of several million miles per hour. Understanding coronal mass ejections and their impact on the Earth is of great interest to both the scientific and technological communities. This book provides an introduction to coronal mass ejections, including a history of their observation and scientific revelations, instruments and theory behind their detection and measurement, and the status quo of theories describing...

  17. First mass measurements at LHCb

    CERN Multimedia

    Bressieux, J

    2011-01-01

    The LHC opens new frontiers in heavy flavour physics through an unprecedented statistical reach for a variety of interesting states produced in pp collisions. The LHCb spectrometer provides a good mass resolution and is suitable for spectroscopy studies. We present first preliminary mass measurements of several $b$ hadrons and of the exotic $X(3872)$ meson, reconstructed in final states containing a $J/\\psi$ using the data collected in 2010 by the LHCb experiment. An important aspect of the analysis is the calibration of the momentum scale using $J/\\psi \\to \\mu^+ \\mu^-$ decays, as well as the control of systematic uncertainties. While the already very competitive mass measurements for the $B^+$, $B^0$ and $B^0_s$ mesons receive similar contributions from systematic and statistical uncertainties, those of the $\\Lambda_b$, $B^+_c$ and $X(3872)$ particles are dominated by statistical uncertainties, and will therefore substantially improve with more data in the future.

  18. Secondary ion mass spectroscopy (SIMS)

    International Nuclear Information System (INIS)

    Naik, P.K.

    1975-01-01

    Secondary Ion Mass Spectrometry (SIMS) which is primarily a method for investigating the chemical composition of the uppermost atomic layer of solid surfaces is explained. In this method, the specimen is bombarded with a primary positive ion beam of small current density monolayer. Positive and negative ions sputtered from the specimen are mass analysed to give the surface chemical composition. The analytical system which consists of a primary ion source, a target manipulator and a mass spectrometer housed in an ultrahigh vacuum system is described. This method can also be used for profile measurements in thin films by using higher current densities of the primary ions. Fields of application such as surface reactions, semiconductors, thin films emission processes, chemistry, metallurgy are touched upon. Various aspects of this method such as the sputtering process, instrumentation, and applications are discussed. (K.B.)

  19. Representative mass reduction in sampling

    DEFF Research Database (Denmark)

    Petersen, Lars; Esbensen, Harry Kim; Dahl, Casper Kierulf

    2004-01-01

    We here present a comprehensive survey of current mass reduction principles and hardware available in the current market. We conduct a rigorous comparison study of the performance of 17 field and/or laboratory instruments or methods which are quantitatively characterized (and ranked) for accuracy...... dividers, the Boerner Divider, the ??spoon method??, alternate/fractional shoveling and grab sampling. Only devices based on riffle splitting principles (static or rotational) passes the ultimate representativity test (with minor, but significant relative differences). Grab sampling, the overwhelmingly...... most often used mass reduction method, performs appallingly?its use must be discontinued (with the singular exception for completely homogenized fine powders). Only proper mass reduction (i.e. carried out in complete compliance with all appropriate design principles, maintenance and cleaning rules) can...

  20. Protein Analysis by Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Cindic, M.

    2008-04-01

    Full Text Available Soft ionization techniques, electrospray (ESI and matrix-assisted laser desorption/ionization (MALDI make the analysis of biomolecules by mass spectrometry (MS possible. MS is used for determination of the molecular weight of peptides and protein, sequence analysis, characterization of protein-ligand interactions etc. The detection limit, resolution and mass accuracy depend on instrument used (Table 1. Impurities (buffers, salts, detergents can reduce the ion intensities or even totally suppress them, so a separation method (chromatography, 2D-gel electrophoresis must be used for purification of the sample.Molecular mass of intact protein can be determined by ESI or MALDI MS. Multiply charged ions are produced by ESI MS, while singly charged ions are predominant in MALDI spectra (Fig. 2.Sequence analysis of proteins by MS can be performed using peptide mass fingerprint. In this method, proteins are separated by 2-D gel electrophoresis and digested with specific protease (Table 2 or digested and then separated by two-dimensional chromatography (Fig. 1. The obtained peptide mixtures are analyzed by MS or MALDI-TOF technique. The masses determined by MS are compared with calculated masses from database entries. Different algorithms have been developed for protein identification. Example of posttranslational modifications (N- and O-glycosylation and protein sequence complex analysis after dual digestion (endoproteinase digestion followed by endoglycosidase digestion is shown in Fig. 3.It is known that detection of peptides by MS is influenced by intrinsic properties like amino acid composition, the basicity of the C-terminal amino acid, hydrophobicity, etc. Arginine-containing peptides dominate in MS spectra of tryptic digest, so the chemical derivatization of lysine terminal residue by O-methilisourea or 2-methoxy-4,5-1H-imidazole was suggested (Fig. 4.The peptide mass fingerprint method can be improved further by peptide fragmentation using tandem

  1. Boundaries of mass resolution in native mass spectrometry

    NARCIS (Netherlands)

    Lössl, Philip|info:eu-repo/dai/nl/371559693; Snijder, Joost|info:eu-repo/dai/nl/338018328; Heck, Albert J R|info:eu-repo/dai/nl/105189332

    Over the last two decades, native mass spectrometry (MS) has emerged as a valuable tool to study intact proteins and noncovalent protein complexes. Studied experimental systems range from small-molecule (drug)-protein interactions, to nanomachineries such as the proteasome and ribosome, to even

  2. Eleventh ISMAS workshop on mass spectrometry

    International Nuclear Information System (INIS)

    Aggarwal, S.K.; Jaison, P.G.

    2004-10-01

    This volume deals with the latest developments in this field, exposing the innumerable applications of mass spectrometry. The topics covered include basic fundamentals of mass spectrometry, qualitative and quantitative aspects and data interpretation, maintenance of mass spectrometers, selection of a mass spectrometer, its applications in various branches of science as well as recent advances in mass spectrometry. Emphasis is also laid on the practical aspects of mass spectrometry. Papers relevant to INIS are indexed separately

  3. Accelerator-based ultrasensitive mass spectrometry

    International Nuclear Information System (INIS)

    Gove, H.E.

    1985-01-01

    This chapter describes a new mass spectrometry technique involving charged particle accelerators normally used for basic research in nuclear science. Topics considered include the limitations of conventional mass spectrometry, the limitations of the direct measurement of radioactive decay, mass spectrometry using a tandem electrostatic accelerator, mass spectrometry using a cyclotron, how accelerator mass spectrometry circumvents the limitations of conventional mass spectrometry, measurements of stable isotopes, nuclear physics and astrophysics applications, modifications to existing accelerators, descriptions of dedicated systems, and future applications

  4. Neutrino mass matrix and hierarchy

    International Nuclear Information System (INIS)

    Kaus, Peter; Meshkov, Sydney

    2003-01-01

    We build a model to describe neutrinos based on strict hierarchy, incorporating as much as possible, the latest known data, for Δsol and Δatm, and for the mixing angles determined from neutrino oscillation experiments, including that from KamLAND. Since the hierarchy assumption is a statement about mass ratios, it lets us obtain all three neutrino masses. We obtain a mass matrix, Mν and a mixing matrix, U, where both Mν and U are given in terms of powers of Λ, the analog of the Cabibbo angle λ in the Wolfenstein representation, and two parameters, ρ and κ, each of order one. The expansion parameter, Λ, is defined by Λ2 = m2/m3 = √(Δsol/Δatm) ≅ 0.16, and ρ expresses our ignorance of the lightest neutrino mass m1, (m1 ρΛ4m3), while κ scales s13 to the experimental upper limit, s13 = κΛ2 ≅ 0.16κ. These matrices are similar in structure to those for the quark and lepton families, but with Λ about 1.6 times larger than the λ for the quarks and charged leptons. The upper limit for the effective neutrino mass in double β-decay experiments is 4 x 10-3eV if s13 = 0 and 6 x 10-3eV if s13 is maximal. The model, which is fairly unique, given the hierarchy assumption and the data, is compared to supersymmetric extension and texture zero models of mass generation

  5. Mass generation in composite models

    International Nuclear Information System (INIS)

    Peccei, R.D.

    1985-10-01

    I discuss aspects of composite models of quarks and leptons connected with the dynamics of how these fermions acquire mass. Several issues related to the protection mechanisms necessary to keep quarks and leptons light are illustrated by means of concrete examples and a critical overview of suggestions for family replications is given. Some old and new ideas of how one may actually be able to generate small quark and lepton masses are examined, along with some of the difficulties they encounter in practice. (orig.)

  6. Leptogenesis. Theory and neutrino masses

    Energy Technology Data Exchange (ETDEWEB)

    Buchmueller, W.

    2012-12-15

    After a brief discussion of baryon and lepton number nonconservation, we review the status of thermal leptogenesis with GUT scale neutrino masses, as well as low scale alternatives with keV neutrinos as dark matter and heavy neutrino masses within the reach of the LHC. Recent progress towards a full quantum mechanical description of leptogenesis is described with resonant leptogenesis as an application. Finally, cosmological B-L breaking after inflation is considered as origin of the hot early universe, generating entropy, baryon asymmetry and dark matter.

  7. Mass Estimation and Its Applications

    Science.gov (United States)

    2012-02-23

    parameters); e.g., the rect- angular kernel function has fixed width or fixed per unit size. But the rectangular function used in mass has no parameter...MassTER is implemented in JAVA , and we use DBSCAN in WEKA [13] and a version of DENCLUE implemented in R (www.r-project.org) in our empirical evaluation...Proceedings of SIGKDD, 2010, 989-998. [13] I.H. Witten and E. Frank, Data Mining: Practical Machine Learning Tools and Techniques with Java Implementations

  8. Mass spectrometry for biomarker development

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Chaochao; Liu, Tao; Baker, Erin Shammel; Rodland, Karin D.; Smith, Richard D.

    2015-06-19

    Biomarkers potentially play a crucial role in early disease diagnosis, prognosis and targeted therapy. In the past decade, mass spectrometry based proteomics has become increasingly important in biomarker development due to large advances in technology and associated methods. This chapter mainly focuses on the application of broad (e.g. shotgun) proteomics in biomarker discovery and the utility of targeted proteomics in biomarker verification and validation. A range of mass spectrometry methodologies are discussed emphasizing their efficacy in the different stages in biomarker development, with a particular emphasis on blood biomarker development.

  9. Mass spectrometry. [review of techniques

    Science.gov (United States)

    Burlingame, A. L.; Kimble, B. J.; Derrick, P. J.

    1976-01-01

    Advances in mass spectrometry (MS) and its applications over the past decade are reviewed in depth, with annotated literature references. New instrumentation and techniques surveyed include: modulated-beam MS, chromatographic MS on-line computer techniques, digital computer-compatible quadrupole MS, selected ion monitoring (mass fragmentography), and computer-aided management of MS data and interpretation. Areas of application surveyed include: organic MS and electron impact MS, field ionization kinetics, appearance potentials, translational energy release, studies of metastable species, photoionization, calculations of molecular orbitals, chemical kinetics, field desorption MS, high pressure MS, ion cyclotron resonance, biochemistry, medical/clinical chemistry, pharmacology, and environmental chemistry and pollution studies.

  10. Quark mass effects in QCD

    International Nuclear Information System (INIS)

    Shirkov, D.V.

    1982-01-01

    In this paper recent studies of invariant QCD coupling anti asub(s)(Qsup(2)) in the 2-loop approximation with account of fermionic mass effects are summarized. The main results are: An explicit expression for anti asub(s)(Qsup(2)) in the 2-loop approximation with accurate account of heavy quark masses. A quantitative analysis on the basis of the above-mentioned expression for anti asub(s)(Qsup(2)) of the energy dependence of the scale QCD parameter ν and the conclusion about its inadequacy in the modern energy range

  11. Functional genomics by mass spectrometry

    DEFF Research Database (Denmark)

    Andersen, Jens S.; Mann, M

    2000-01-01

    Systematic analysis of the function of genes can take place at the oligonucleotide or protein level. The latter has the advantage of being closest to function, since it is proteins that perform most of the reactions necessary for the cell. For most protein based ('proteomic') approaches to gene f...... numbers of intact proteins by mass spectrometry directly. Examples from this laboratory illustrate biological problem solving by modern mass spectrometric techniques. These include the analysis of the structure and function of the nucleolus and the analysis of signaling complexes....

  12. Mass splitting induced by gravitation

    International Nuclear Information System (INIS)

    Maia, M.D.

    1982-08-01

    The exact combination of internal and geometrical symmetries and the associated mass splitting problem is discussed. A 10-parameter geometrical symmetry is defined in a curved space-time in such a way that it is a combination of de Sitter groups. In the flat limit it reproduces the Poincare-group and its Lie algebra has a nilpotent action on the combined symmetry only in that limit. An explicit mass splitting expression is derived and an estimation of the order of magnitude for spin-zero mesons is made. (author)

  13. Quadrupole Time-of-Flight Mass Spectrometer

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: The system generates superior quality mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data from both atmospheric pressure ionization (API) and...

  14. THEORETICAL FOUNDATIONS EFFICIENT MASS VALUATION

    Directory of Open Access Journals (Sweden)

    Koshel A.

    2016-08-01

    Full Text Available In the article the theoretical basis for determining the effectiveness of mass valuation of land in present-day conditions are described. The concept defenitsy effect and effectiveness as economic categories and their classification values for mass valuation of land are presented. The effectiveness of mass valuation of land in the settlements defines the structure of local budget and economic activities undertaken by local authorities on the basis of the results of the mass appraisal of real estate. Mass valuation is regular and it is characterized by high degree of standardization of procedures and a significant increase in the role of statistical methods for processing data related to the use of the most significant factors influencing the parameters of the object to its cost, as well as the need to determine the value of the objective laws change equivalent, which is only possible when using economic and mathematical methods and statistical analysis. Quality control results of mass valuation carried out principally in other ways, as obtained by applying statistical machine results can be checked as soon statistical methods. This shows the relevance of research topic and lack of elaboration for Ukraine problems of efficiency of mass land valuation. Scientific research conducted through the use of the dialectical method and techniques of abstraction, comparative analysis and synthesis, the article various models and methods of valuation of land for taxation purposes are analyzed. In addition, the group explored methods used, comparisons, and more. In economic theory and practice problems and determine the effect of efficiency aimed at profit is quite relevant. Economists consider cost-effectiveness, such as economic efficiency. In this case, the production can be attributed to the activities to conduct and organization of mass valuation of land. This pushes many different positions on criteria and indicators of economic efficiency, the

  15. Quantitative mass spectrometry: an overview

    Science.gov (United States)

    Urban, Pawel L.

    2016-10-01

    Mass spectrometry (MS) is a mainstream chemical analysis technique in the twenty-first century. It has contributed to numerous discoveries in chemistry, physics and biochemistry. Hundreds of research laboratories scattered all over the world use MS every day to investigate fundamental phenomena on the molecular level. MS is also widely used by industry-especially in drug discovery, quality control and food safety protocols. In some cases, mass spectrometers are indispensable and irreplaceable by any other metrological tools. The uniqueness of MS is due to the fact that it enables direct identification of molecules based on the mass-to-charge ratios as well as fragmentation patterns. Thus, for several decades now, MS has been used in qualitative chemical analysis. To address the pressing need for quantitative molecular measurements, a number of laboratories focused on technological and methodological improvements that could render MS a fully quantitative metrological platform. In this theme issue, the experts working for some of those laboratories share their knowledge and enthusiasm about quantitative MS. I hope this theme issue will benefit readers, and foster fundamental and applied research based on quantitative MS measurements. This article is part of the themed issue 'Quantitative mass spectrometry'.

  16. Consumer Preferences for Mass Customization

    NARCIS (Netherlands)

    B.G.C. Dellaert (Benedict); S. Stremersch (Stefan)

    2004-01-01

    textabstractIncreasingly, firms adopt mass customization, which allows consumers to customize products by self-selecting their most preferred composition of the product for a predefined set of modules. For example, PC vendors such as Dell allow customers to customize their PC by choosing the type of

  17. Neutrino masses and neutrino oscillations

    CERN Document Server

    Di Lella, L

    2000-01-01

    These lectures review direct measurements of neutrino masses and the status of neutrino oscillation searches using both natural neutrino sources (the Sun and cosmic rays interacting in the Earth atmosphere) and artificial neutrinos (produced by nuclear reactors and accelerators). Finally, future experiments and plans are presented. (68 refs).

  18. Higgs mass determination in supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Vega, Javier Pardo [Abdus Salam International Centre for Theoretical Physics, Strada Costiera 11, 34151, Trieste (Italy); SISSA International School for Advanced Studies and INFN Trieste, Via Bonomea 265, 34136, Trieste (Italy); Villadoro, Giovanni [Abdus Salam International Centre for Theoretical Physics, Strada Costiera 11, 34151, Trieste (Italy)

    2015-07-29

    We present the state-of-the-art of the effective field theory computation of the MSSM Higgs mass, improving the existing ones by including extra threshold corrections. We show that, with this approach, the theoretical uncertainty is within 1 GeV in most of the relevant parameter space. We confirm the smaller value of the Higgs mass found in the EFT computations, which implies a slightly heavier SUSY scale. We study the large tan β region, finding that sbottom thresholds might relax the upper bound on the scale of SUSY. We present SUSYHD, a fast computer code that computes the Higgs mass and its uncertainty for any SUSY scale, from the TeV to the Planck scale, even in Split SUSY, both in the (DR)-bar and in the on-shell schemes. Finally, we apply our results to derive bounds on some well motivated SUSY models, in particular we show how the value of the Higgs mass allows to determine the complete spectrum in minimal gauge mediation.

  19. Correlations among static quark masses

    International Nuclear Information System (INIS)

    Lewin, K.; Motz, G.B.

    1987-01-01

    Nonrelativistic heavy quarkonia potentials with Coulomb and linearly rising limiting behaviour are correlated additively by Taylor expansion extracting the limiting structure and a constant term. Relations between fit parameters of different potentials including the quark masses m b and m c , are obtained. The known stability of the difference m b -m c , appears as direct consequence of flavour invariance of the potentials

  20. Mass spectrometry in epigenetic research

    DEFF Research Database (Denmark)

    Beck, Hans Christian

    2010-01-01

    cancers has gained tremendous interest in recent years, and many of these inhibitors are currently undergoing clinical trials. Despite intense research, however, the exact molecular mechanisms of action of these molecules remain, to a wide extent, unclear. The recent application of mass spectrometry...

  1. Mass-Selective Laser Photoionization.

    Science.gov (United States)

    Smalley, R. E.

    1982-01-01

    Discusses the nature and applications of mass-selective laser photoionization. The ionization can be done with a single intense laser pulse lasting a few billionths of a second with no molecular fragmentation. Applications focus on: (1) benzene clusters, excimers, and exciplexes; (2) metal clusters; and (3) triplet formation and decay. (Author/JN)

  2. Possible nonvanishing mass of photon

    International Nuclear Information System (INIS)

    Nakazato, Hiromichi; Namiki, Mikio; Yamanaka, Yoshiya; Yokoyama, Kan-ichi.

    1985-05-01

    From phenomenological and field-theoretical considerations on photon mass, we first show that photon is not limitted to being massless at the present stage. Next we illustrate a possibility of formulating a local field theory for massive photons coupled with nonconserved currents, while we cannot do for massless photons. (author)

  3. Health Education and Mass Communications.

    Science.gov (United States)

    Snegroff, Stanley

    1983-01-01

    Health educators should be able to use mass comunications media and should be knowledgeable about the most recent media theories, methods, and technologies. Suggestions for making effective use of television, newspapers, and other media for disseminating health information and for conducting media campaigns are given. (PP)

  4. Determination of the neutron mass

    International Nuclear Information System (INIS)

    Amador V, P.; Chacon R, A.; Arcos P, A.; Rodriguez N, S.; Pinedo S, A.; Vega C, H.R.

    2005-01-01

    The binding energy of the deuteron was measured and it was determined the neutron mass starting from the nuclear reaction, 1 0 n + 1 1 H → 2 1 D + γ. The produced photon is soon a gamma ray that is emitted when the hydrogen captures a thermal neutron. The photon energy was measured using two spectrometric systems for gamma rays. A system with a detector of NaI(TI) of 3'' x 3'' and the other one with a High-purity Germanium detector. The first detector has a bigger efficiency and a smaller resolution in comparison with the second detector. The energy of the measured photon is the binding energy of the deuteron. With the measurement of the photon energy and the masses of the proton and of the deuterium it was determined the neutron mass. The value of the mass obtained with both systems it was compared with the value reported in the literature. The nuclear reaction was induced in a volume of paraffin that it was bombing with a source 239 PuBe whose activity is of 3.7 x 10 10 Bq. (Author)

  5. Gravity and body mass regulation

    Science.gov (United States)

    Warren, L. E.; Horwitz, B. A.; Fuller, C. A.

    1997-01-01

    The effects of altered gravity on body mass, food intake, energy expenditure, and body composition are examined. Metabolic adjustments are reviewed in maintenance of energy balance, neural regulation, and humoral regulation are discussed. Experiments with rats indicate that genetically obese rats respond differently to hypergravity than lean rats.

  6. Theme Issue on Mass Communication.

    Science.gov (United States)

    Anapol, Malthon M., Ed.

    1978-01-01

    Focusing on issues in mass communication, the six articles in this journal issue cover many facets and approaches to the topics. The first article offers a review of recent developments in the field and some comments about its future. The second article reviews feminism in comedies from the 1930s and in a current film, and the third analyzes the…

  7. Secrets of a Mass Grave

    Science.gov (United States)

    Ament, Caitlin Marie; Graham, Theodore J.

    2017-01-01

    This article presents a unit of study in which students examine skeletons and draw conclusions from the evidence they find in a simulated mass grave. The activity involves the foundation of forensic anthropology--interpreting the structure of skeletal remains to determine sex, age, height, and possible cause of death. Working through a series of…

  8. Maximum stellar iron core mass

    Indian Academy of Sciences (India)

    60, No. 3. — journal of. March 2003 physics pp. 415–422. Maximum stellar iron core mass. F W GIACOBBE. Chicago Research Center/American Air Liquide ... iron core compression due to the weight of non-ferrous matter overlying the iron cores within large .... thermal equilibrium velocities will tend to be non-relativistic.

  9. Top mass measurement at CDF

    International Nuclear Information System (INIS)

    Rolli, S.

    1996-06-01

    We present the measurement of the top quark mass using L = 110 pb -1 data sample of pp collisions at √s = 1.8 TeV collected with the Collider Detector at Fermilab (CDF). We show the results for the different channels and discuss with some emphasis the determination of the systematic uncertainties. 7 refs., 10 figs., 5 tabs

  10. Missing mass of the Universe

    International Nuclear Information System (INIS)

    Mazure, A.

    1989-01-01

    The first evidence for missing mass or dark matter comes from the 30's. On one hand, Oort noted that in the solar neighbourhood the mass of the stars (inferred from count numbers) cannot account for their observed velocities. On the other hand, observation on the sky of various galaxy condensations like the Coma cluster let suppose that they are actual bound systems and not only statistical fluctuations. However, with such an assumption, Zwicky concluded that the velocity dispersion of galaxies in Coma required 100 times more mass than contained in galaxies. Since this period, refined observations, analyses and a reevaluation of the cosmic distance scale reduced this factor but the problem is still present. It is particularly striking for spiral galaxies where systematic observations of rotation curves lead to infer the presence of spherical massive halos. These dynamical evidences form the first missing mass problem. The second one appears with the development of Great Unified Theories for which the natural laboratory is the very early Universe. A consequence of these theories is that our Universe could be closed by exotic particles which interact only gravitationally [fr

  11. Mass chest radiography in Greece

    International Nuclear Information System (INIS)

    Papavasiliou, C.

    1987-01-01

    In Greece mass chest radiography has been performed regularly on various population groups as a measure to control tuberculosis. Routine chest radiography is performed in most Greek hospitals on admission. In this report available data-admittedly inadequate-directly or indirectly addressing the problem of benefit versus the risk or cost associated with this examination is presented

  12. Mass spectrometry of large molecules

    International Nuclear Information System (INIS)

    Facchetti, S.

    1985-01-01

    The lectures in this volume were given at a course on mass spectrometry of large molecules, organized within the framework of the Training and Education programme of the Joint Research Centre of the European Communities. Although first presented in 1983, most of the lectures have since been updated by their authors. (orig.)

  13. Mass Customization of process plants

    DEFF Research Database (Denmark)

    Hvam, Lars

    2006-01-01

    This case study describes how F.L.Smidth A/S, a manufacturer of large processing plants for cement production, has applied the principles of mass customisation in the area of highly complex, custom engineered products. The company has based its sales process on a configuration system to achieve...

  14. Mass Customization and Performance Assessment

    DEFF Research Database (Denmark)

    Storbjerg, Simon Haahr; Brunø, Thomas Ditlev; Nielsen, Kjeld

    2014-01-01

    Mass customization (MC) has been introduced as the future of manufacturing, and great results have been proven. Recent research, however, documents a high failure rate for companies trying to adapt to MC as a business strategy. Making this transition is, as highlighted by several scholars...

  15. Competitive Effects of Mass Customization

    OpenAIRE

    Oksana Loginova

    2010-01-01

    Earlier theoretical literature on mass customization maintains that customization reduces product differentiation and intensifies price competition. In contrast, operations management studies argue that customization serves primarily to differentiate a company from its competitors. Interactive involvement of the customer in product design creates an affective relationship with the firm, relaxing price competition. This paper provides a model that incorporates consumer involvement to explain t...

  16. Mass spectrometry with particle accelerator

    International Nuclear Information System (INIS)

    Anon.

    1983-01-01

    The heavy ion accelerator use is renewing the ultrasensitive mass spectrometry in extending the detection limits. These new devices allow the measurement of rare isotope ratio, as 10 Be, 14 C, 26 Al, 36 Cl or 41 Ca, from the earth natural reservoirs [fr

  17. On renormalization-invariant masses

    International Nuclear Information System (INIS)

    Fleming, H.; Furuya, K.

    1978-02-01

    It is shown that spontaneous generation of renormalization invariant mass is possible in infra-red stable theories with more than one coupling constant. If relations among the coupling constants are permitted the effect can be made compatible with pertubation theory

  18. New Results on Cepheid Masses

    Science.gov (United States)

    Evans, N. R.; Bohm-Vitense, E.; Carpenter, K.; Robinson, R.; Beck-Winchatz, B.

    1996-12-01

    Masses for Cepheid variable stars can be measured by combining the orbital velocity amplitude for the Cepheid (from a ground-based orbit) with the orbital velocity amplitude of a hot main sequence companion (observed in the ultraviolet from satellites such as IUE and HST) and the mass of the companion (inferred from from the ultraviolet energy distribution). Observations of 5 binary systems are now completed or in progress with the Goddard High Resolution Spectrograph on the Hubble Space Telescope. Recently completed observations of U Aql lead to a mass of 5.1 +/- 1.1 Msun . We will discuss the results for S Mus, V350 Sgr, U Aql, and Y Car, and the constraints they place on stellar evolution calculations. As would be expected, some of the B companions have high rotational velocities, decreasing the accuracy with which their orbital velocities can be measured. The preliminary conclusion from the 4 HST targets and SU Cyg (mass from IUE observations) is that a weighted mean indicates no convective overshoot but the mode (which reflects the HST results better) agrees with the modest overshoot used in the Geneva evolutionary calculations. Financial Support was provided by a NASA grant GO-4541-01 to EB--V and GO-4541.02 to KGC, a grant from the Natural Sciences and Engineering Council, Canada to NRE, from the AXAF Science Center NASA Contract NAS8-39073.

  19. Systems of neutrinos with mass

    International Nuclear Information System (INIS)

    Groot, S.R. de

    1984-01-01

    From the formalism of relativistic kinetic theory and the weak interaction Lagrangian the volume viscosity of a massive neutrino system is derived. Its value is calculated as a function of the neutrino mass and the temperature. Its role in the way of expanding or contraction of neutrino clouds in the universe is discussed. (Author) [pt

  20. Mass Media in the Classroom.

    Science.gov (United States)

    Firth, Brian

    The teacher is provided with a range of practical suggestions for teaching about mass media. Chapters are devoted to the press, magazines, television, advertising, and film. The author argues that the teacher must start from the place of the various media in the lives of the children and not from a desire to instruct the children as to what they…

  1. Intermediate-Mass Black Holes

    Science.gov (United States)

    Miller, M. Coleman; Colbert, E. J. M.

    2004-01-01

    The mathematical simplicity of black holes, combined with their links to some of the most energetic events in the universe, means that black holes are key objects for fundamental physics and astrophysics. Until recently, it was generally believed that black holes in nature appear in two broad mass ranges: stellar-mass (M~3 20 M⊙), which are produced by the core collapse of massive stars, and supermassive (M~106 1010 M⊙), which are found in the centers of galaxies and are produced by a still uncertain combination of processes. In the last few years, however, evidence has accumulated for an intermediate-mass class of black holes, with M~102 104 M⊙. If such objects exist they have important implications for the dynamics of stellar clusters, the formation of supermassive black holes, and the production and detection of gravitational waves. We review the evidence for intermediate-mass black holes and discuss future observational and theoretical work that will help clarify numerous outstanding questions about these objects.

  2. Mass spectrometric analysis of lithium

    International Nuclear Information System (INIS)

    Chitambar, S.A.; Kavimandan, V.D.; Aggarwal, S.K.; Ramasubramanian, P.A.; Shah, P.M.; Almoula, A.I.; Acharya, S.N.; Parab, A.R.; Jain, H.C.; Mathews, C.K.; Ramaniah, M.V.

    1978-01-01

    The details of investigations carried out on the isotopic analysis of lithium using surface ionisation mass spectrometry are presented. Various parameters affecting the precision in isotopic analysis of lithium are discussed. A precision of 1% is achieved in the relative isotope abundance measurement. (author)

  3. Mass spectrometry and tandem mass spectrometry of citrus limonoids.

    Science.gov (United States)

    Tian, Qingguo; Schwartz, Steven J

    2003-10-15

    Methods for atmospheric pressure chemical ionization tandem mass spectrometry (APCI-MS/MS) of citrus limonoid aglycones and electrospray ionization tandem mass spectrometry (ESI-MS/MS) of limonoid glucosides are reported. The fragmentation patterns of four citrus limonoid aglycones (limonin, nomilin, obacunone, and deacetylnomilin) and six limonoid glucosides, that is, limonin 17-beta-D-glucopyranoside (LG), nomilin 17-beta-D-glucopyranoside (NG), nomilinic acid 17-beta-D-glucopyranoside (NAG), deacetyl nomilinic acid 17-beta-D-glucopyranoside (DNAG), obacunone 17-beta-D-glucopyranoside (OG), and obacunoic acid 17-beta-D-glucopyranoside (OAG) were investigated using a quadruple mass spectrometer in low-energy collisionally activated dissociation (CAD). The four limonoid aglycones and four limonoid glucosides (LG, OG, NAG, and DNAG) were purified from citrus seeds; the other two limonoid glucosides (NG and OAG) were tentatively identified in the crude extract of grapefruit seeds by ESI mass spectrometry in both positive and negative ion analysis. Ammonium hydroxide or acetic acid was added to the mobile phase to facilitate ionization. During positive ion APCI analysis of limonoid aglycones, protonated molecular ion, [M + H]+, or adduct ion, [M + NH3 + H]-, was formed as base peaks when ammonium hydroxide was added to the mobile phase. Molecular anions or adduct ions with acetic acid ([M + HOAc - H] and [M + HOAc]-) or a deprotonated molecular ion were produced during negative ion APCI analysis of limonoid aglycones, depending on the mobile-phase modifier used. Positive ion ESI-MS of limonoid glucosides produced adduct ions of [M + H + NH3]+, [M + Na]+, and [M + K]+ when ammonium hydroxide was added to the mobile phase. After collisionally activated dissociation (CAD) of the limonoid aglycone molecular ions in negative ion APCI analysis, fragment ions indicated structural information of the precursor ions, showing the presence of methyl, carboxyl, and oxygenated ring

  4. Computed tomography of mediastinal masses

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, Seong Tae; Lee, Jae Mun; Bahk, Yong Whee; Kim, Choon Yul [Catholic Medical College, Seoul (Korea, Republic of)

    1984-09-15

    The ability of CT scanning of the mediastinum to distinguish specific tissue densities and to display in a transverse plane often provides unique diagnostic information unobtainable with conventional radiographic methods. We retrospectively analyzed the CT findings of 20 cases of proven mediastinal masses at the Department of Radiology, St. Mary Hospital , Catholic Medical College from February 1982 to June 1984. CT scans were performed with a Siemens Somatom 2 scanner. The technical factors involved were tube voltage 125 kVp, exposure time 5 seconds, 230 mAs, 256 X 256 matrices, and pixel size 1.3 mm. 8 mm slices were obtained at 1 cm interval from the apex of the lung to the diaphragm. If necessary, additional scans at 5 mm interval or magnify scans were obtained. After pre-contrast scan, contrast scans were routinely taken with rapid drip-infusion of contrast media (60% Convey, 150 cc). The results obtained were as follows; 1. Among 20 cases, 11 were tumors, 4 infectious masses and 5 aneurysms of great vessels, tortuous brachiocephalic artery and pericardial fat pad. In each case CT showed accurate location, extent, and nature of the masses. 2. Solid tumors were thymic hyperplasias, thymoma, thymus carcinoid, neurilemmoma and germ cell tumors (seminoma, embryonal cell carcinoma). Internal architecture was homogeneous in thymoma, thymus carcinoid, neurilemmoma, seminoma but inhomogeneous in thymic hyperplasias and embryonal cell carcinoma. CT numbers ranged from 16 to 49 HU and were variably enhanced. 3. Cystic tumors consisted of teratomas, cystic hygroma, and neurilemmoma. Teratomas contained calcium and fat, inhomogeneous mass with strongly enhancing wall. Cystic hygroma was nonenhancing mass with HU of 20. 4. All of germ cell tumors (2 teratomas and one each of seminoma and embryonal cell carcinoma) and one of 2 thymic hyperplasias had calcium deposit. 5. Tuberculous lymphadenopathies presented as a mass in the retrocaval pretracheal space and hilar region

  5. Ultrasound guided aspiration cytology of neck mass except thyroid mass

    International Nuclear Information System (INIS)

    Kim, Myeong Jin; Lee, Jong Tae; Yoo, Hyung Sik; Suh, Jung Ho; Park, Cheong Soo; Lee, Gwang Gil

    1988-01-01

    Results of ultrasound guided aspiration cytology of extrathyroidal neck masses of 73 patients were reviewed. Included cases were 23 malignant lesions; 16 metastatic tumors, 4 lymphomas, 3 salivary gland tumors and 50 benign lesions: 24 tuberculous lymphadenites, 15 abscess, 3 benign lymph node hyperplasias, etc. There were one case of false negative and none of false positive result for malignancy. In two cases of malignancy, insufficient cellular material was obtained. In one case of lymphoma, and a benign lymph node hyperplasia, it was difficult to distinguish between benignancy and malignancy on cytologic smear. For the malignant lesions, sensitivity was 83%, specificity was 98%, and overall accuracy was 93%. There were none who had suffered adverse effect from the procedure. Ultrasound guided aspiration cytology seems to be simple, accurate and safe diagnostic modality for neck masses especially in condition that malignancy can not be excluded

  6. Finding Mass Constraints Through Third Neutrino Mass Eigenstate Decay

    Science.gov (United States)

    Gangolli, Nakul; de Gouvêa, André; Kelly, Kevin

    2018-01-01

    In this paper we aim to constrain the decay parameter for the third neutrino mass utilizing already accepted constraints on the other mixing parameters from the Pontecorvo-Maki-Nakagawa-Sakata matrix (PMNS). The main purpose of this project is to determine the parameters that will allow the Jiangmen Underground Neutrino Observatory (JUNO) to observe a decay parameter with some statistical significance. Another goal is to determine the parameters that JUNO could detect in the case that the third neutrino mass is lighter than the first two neutrino species. We also replicate the results that were found in the JUNO Conceptual Design Report (CDR). By utilizing Χ2-squared analysis constraints have been put on the mixing angles, mass squared differences, and the third neutrino decay parameter. These statistical tests take into account background noise and normalization corrections and thus the finalized bounds are a good approximation for the true bounds that JUNO can detect. If the decay parameter is not included in our models, the 99% confidence interval lies within The bounds 0s to 2.80x10-12s. However, if we account for a decay parameter of 3x10-5 ev2, then 99% confidence interval lies within 8.73x10-12s to 8.73x10-11s.

  7. Neutrino mass models and CP violation

    International Nuclear Information System (INIS)

    Joshipura, Anjan S.

    2011-01-01

    Theoretical ideas on the origin of (a) neutrino masses (b) neutrino mass hierarchies and (c) leptonic mixing angles are reviewed. Topics discussed include (1) symmetries of neutrino mass matrix and their origin (2) ways to understand the observed patterns of leptonic mixing angles and (3)unified description of neutrino masses and mixing angles in grand unified theories.

  8. Neutrino mass and the solar neutrino problem

    International Nuclear Information System (INIS)

    Wolfenstein, L.

    1987-01-01

    Theoretical ideas about neutrino mass based on grand-unified theories are reviewed. These give the see-saw formula in which neutrino mass is inversely proportional to a large mass scale M. For M between 10/sup 11/ and 10/sup 15/ Gev the study of solar neutrinos appears to be the best probe of neutrino masses and mixings

  9. The low-luminosity stellar mass function

    International Nuclear Information System (INIS)

    Kroupa, Pavel; Tout, C.A.; Gilmore, Gerard

    1990-01-01

    The stellar mass function for low-mass stars is constrained using the stellar luminosity function and the slope of the mass-luminosity relation. We investigate the range of mass functions for stars with absolute visual magnitude fainter than M V ≅ +5 which are consistent with both the local luminosity function and the rather poorly determined mass-absolute visual magnitude relation. Points of inflexion in the mass-luminosity relation exist because of the effects of H - , H 2 and of other molecules on the opacity and equation of state. The first two of these correspond to absolute magnitudes M V ≅ +7 and M V ≅ +12, respectively, at which structure is evident in the stellar luminosity function (a flattening and a maximum, respectively). Combining the mass-luminosity relation which shows these inflexion points with a peaked luminosity function, we test smooth mass functions in the mass range 0.9-0.1 the solar mass. (author)

  10. Fermion mass hierarchies in theories of technicolor

    International Nuclear Information System (INIS)

    Peskin, M.E.

    1981-01-01

    Models in which light fermion masses result from dynamical symmetry breaking often produce these masses in a hierarchial pattern. The author exhibits two scenarios for obtaining such hierarchies and illustrates each with a simple model of mass generation. In the first scenario, the light fermion masses are separated by powers of a weak coupling constant; in the second scenario, they are separated by a ratio of large mass scales

  11. Mass loss on the Asymptotic Giant Branch

    OpenAIRE

    Zijlstra, Albert

    2006-01-01

    Mass loss on the Asymptotic Giant Branch provides the origin of planetary nebulae. This paper reviews several relevant aspects of AGB evolution: pulsation properties, mass loss formalisms and time variable mass loss, evidence for asymmetries on the AGB, binarity, ISM interaction, and mass loss at low metallicity. There is growing evidence that mass loss on the AGB is already asymmetric, but with spherically symmetric velocity fields. The origin of the rings may be in pulsational instabilities...

  12. Neutrino mass textures with maximal CP violation

    International Nuclear Information System (INIS)

    Aizawa, Ichiro; Kitabayashi, Teruyuki; Yasue, Masaki

    2005-01-01

    We show three types of neutrino mass textures, which give maximal CP violation as well as maximal atmospheric neutrino mixing. These textures are described by six real mass parameters: one specified by two complex flavor neutrino masses and two constrained ones and the others specified by three complex flavor neutrino masses. In each texture, we calculate mixing angles and masses, which are consistent with observed data, as well as Majorana CP phases

  13. Imaging Mass Spectrometry in Neuroscience

    Science.gov (United States)

    2013-01-01

    Imaging mass spectrometry is an emerging technique of great potential for investigating the chemical architecture in biological matrices. Although the potential for studying neurobiological systems is evident, the relevance of the technique for application in neuroscience is still in its infancy. In the present Review, a principal overview of the different approaches, including matrix assisted laser desorption ionization and secondary ion mass spectrometry, is provided with particular focus on their strengths and limitations for studying different neurochemical species in situ and in vitro. The potential of the various approaches is discussed based on both fundamental and biomedical neuroscience research. This Review aims to serve as a general guide to familiarize the neuroscience community and other biomedical researchers with the technique, highlighting its great potential and suitability for comprehensive and specific chemical imaging. PMID:23530951

  14. Ion detection in mass spectrometry

    International Nuclear Information System (INIS)

    Bolbach, Gerard

    2016-03-01

    This course aims at providing some elements for a better understanding of ion detectors used in mass spectrometers, of their operations, and of their limitations. A first part addresses the functions and properties of an ideal detector, how to detect ions in gas phase, and particle detectors and ion detectors used in mass spectrometry. The second part proposes an overview of currently used detectors with respect to their operation principle: detection from the ion charge (Faraday cylinder), detection by inductive effects (FTICR, Fourier Transform Ion Cyclotron Resonance), and detection by secondary electron emission. The third part discusses the specificities of secondary electron emission. The fourth one addresses operating modes and parameters related to detectors. The sixth part proposes a prospective view on future detectors by addressing the following issues: cryo-detector, inductive effect and charge detectors, ion detection and nano materials

  15. Electromagnetic corrections to baryon masses

    International Nuclear Information System (INIS)

    Durand, Loyal; Ha, Phuoc

    2005-01-01

    We analyze the electromagnetic contributions to the octet and decuplet baryon masses using the heavy-baryon approximation in chiral effective field theory and methods we developed in earlier analyses of the baryon masses and magnetic moments. Our methods connect simply to Morpurgo's general parametrization of the electromagnetic contributions and to semirelativistic quark models. Our calculations are carried out including the one-loop mesonic corrections to the basic electromagnetic interactions, so to two loops overall. We find that to this order in the chiral loop expansion there are no three-body contributions. The Coleman-Glashow relation and other sum rules derived in quark models with only two-body terms therefore continue to hold, and violations involve at least three-loop processes and can be expected to be quite small. We present the complete formal results and some estimates of the matrix elements here. Numerical calculations will be presented separately

  16. A Revolt of the Masses

    DEFF Research Database (Denmark)

    Andersen, Katrine Helene

    2017-01-01

    This article discusses the consolidation of mass culture in early 20th century Spain and analyses the discrepancy between the intellectual debate about Spanish culture and public behaviour. Bullfighting has throughout history been a much debated theme amongst intellectuals, and it has been banned...... by kings and the Church on several occasions. Nevertheless, there has always been an audience. In early 20th century, football entered the scene of popular culture in Spain and gained very quickly in popularity. The article discusses the presence of the two and analyses the contribution of bullfighting...... and football to the process of modernisation and globalisation in Spain. José Ortega y Gasset’s view on culture as a production of value and his idea of the revolt of the masses serves as a prime theoretical backdrop for the study....

  17. Direct measurements of neutrino mass

    International Nuclear Information System (INIS)

    Robertson, R.G.H.

    1991-01-01

    Some recent developments in the experimental search for neutrino mass are discussed. New data from Los Alamos on the electron neutrino mass as measured in tritium beta decay give an upper limit of 9.3 eV at the 95% confidence level. This result is not consistent with the long-standing ITEP result of 26(5) eV within a ''model-independent'' range of 17 to 40 eV. It now appears that the electron neutrino is not sufficiently massive to close the universe by itself. Hime and Jelley report finding new evidence for a 17-keV neutrino in the Β decay of 35 S and 63 Ni. Many other experiments are being reported and the situation is still unresolved. 56 refs., 1 fig., 3 tabs

  18. Midline Craniofacial Masses in Children

    OpenAIRE

    Van Wyhe, Renae D.; Chamata, Edward S.; Hollier, Larry H.

    2016-01-01

    Nasal dermoids, encephaloceles, and gliomas are rare congenital lesions that result from improper embryologic development. The differentiation between them and a firm understanding of their pathology is necessary to avoid unnecessary complications. In view of their potential intracranial connection, prompt diagnosis and treatment are paramount. The authors review the embryology, diagnoses, radiologic work-up, surgical management, and complications of these midline craniofacial masses in child...

  19. Sarcoidosis presenting as penile mass

    Directory of Open Access Journals (Sweden)

    Hüseyin Semiz

    2017-01-01

    Full Text Available Sarcoidosis is an inflammatory disease with unknown cause characterized by noncaseating granuloma formations. It may present with bilateral hilar lymphadenopathy, skin lesions, eye, and musculoskeletal system involvement. Rare involvement of the genital organs (prostate, testis, epididymis has also been reported. However, penile involvement is observed quite rare. In this paper, we report a patient with penile mass who was diagnosed with sarcoidosis on the basis of the laboratory, radiological, and pathological investigations.

  20. Optics of mass separator I

    International Nuclear Information System (INIS)

    Balestrini, S.J.

    1981-07-01

    The ion optics of an existing mass separator are documented. The elctrostatic and magnetic stages are analyzed theoretically, both separately and in combination, by paying particular attention to the ion trajectories, the linear and angular magnifications, and the dispersion. The possibility of converting the magnet into a tunable unit by means of current-carrying elements in the gap is demonstrated. The feasibility of correction coils constructed from printed circuit board is shown

  1. Optics of mass separator I

    Energy Technology Data Exchange (ETDEWEB)

    Balestrini, S.J.

    1981-07-01

    The ion optics of an existing mass separator are documented. The elctrostatic and magnetic stages are analyzed theoretically, both separately and in combination, by paying particular attention to the ion trajectories, the linear and angular magnifications, and the dispersion. The possibility of converting the magnet into a tunable unit by means of current-carrying elements in the gap is demonstrated. The feasibility of correction coils constructed from printed circuit board is shown.

  2. Neutrino masses and family symmetry

    International Nuclear Information System (INIS)

    Grinstein, B.; Preskill, J.; Wise, M.B.

    1985-01-01

    Neutrino masses in the 100 eV-1 MeV range are permitted if there is a spontaneously broken global family symmetry that allows the heavy neutrinos to decay by Goldstone boson emission with a cosmologically acceptable lifetime. The family symmetry may be either abelian or nonabelian; we present models illustrating both possibilities. If the family symmetry is nonabelian, then the decay tau -> μ + Goldstone boson or tau -> e + Goldstone may have an observable rate. (orig.)

  3. Laser-induced mass spectrometry

    International Nuclear Information System (INIS)

    Polanyi, J.C.

    1981-01-01

    This invention provides a method for the spectroscopic analysis of gas. The gas molecules are internally excited by irradiation with laser light having a wavelength which is absorbed by the sample. The gas is then ionized and passed through a mass spectrometer and the amount of the ionized species in the irradiated and ionized sample is compared with that in a similar ionized but not irradiated sample

  4. Mass Spectrometry Applications for Toxicology

    OpenAIRE

    Mbughuni, Michael M.; Jannetto, Paul J.; Langman, Loralie J.

    2016-01-01

    Toxicology is a multidisciplinary study of poisons, aimed to correlate the quantitative and qualitative relationships between poisons and their physiological and behavioural effects in living systems. Other key aspects of toxicology focus on elucidation of the mechanisms of action of poisons and development of remedies and treatment plans for associated toxic effects. In these endeavours, Mass spectrometry (MS) has become a powerful analytical technique with a wide range of application used i...

  5. The Inflaton and its Mass

    OpenAIRE

    Brout, Robert

    2002-01-01

    In the context of the two fluid model of space-time fluctuations proposed to tame the transplanckian problem encountered in black hole physics, it is postulated that the inflaton is the fluctuation of mode density, ``the vapor component'' of the model. The mass of the inflaton is occasioned by the exchange of degrees of freedom between the ``vapor'' and the ``liquid'', the planckian ``soup'' in which usual ``cisplanckian'' fields propagate. This exchange between vacuum fluctuations is modeled...

  6. Schwinger Model Mass Anomalous Dimension

    CERN Document Server

    Keegan, Liam

    2016-06-20

    The mass anomalous dimension for several gauge theories with an infrared fixed point has recently been determined using the mode number of the Dirac operator. In order to better understand the sources of systematic error in this method, we apply it to a simpler model, the massive Schwinger model with two flavours of fermions, where analytical results are available for comparison with the lattice data.

  7. Teaching English through Mass Media

    Science.gov (United States)

    Tafani, Vilma

    2009-01-01

    This article aims at analyzing the importance of using Mass Media in the classroom and finding the ways how to use Printed and Audio-visual Media. It is the result of an in-depth study, surveys and questionnaires thus trying to make the ideas in this article more trustworthy. It is based not only on the literature review but also on long personal…

  8. The Mainz Neutrino Mass Experiment

    Czech Academy of Sciences Publication Activity Database

    Kraus, C.; Bornschein, L.; Bonn, J.; Bornschein, B.; Flatt, B.; Kovalík, Alojz; Müller, B.; Otten, EW; Schall, JP.; Thummler, T.; Weinheimer, C.

    2005-01-01

    Roč. 143, - (2005), s. 143 ISSN 0920-5632. [International Conference on Neutrino Physics and Astrophysics /21./. Paříž, 14.06.2004-19.06.2004] R&D Projects: GA MŠk 1P04LA213 Institutional research plan: CEZ:AV0Z10480505 Keywords : neutrino mass * tritium beta decay Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 0.875, year: 2005

  9. Body Mass Index and Stroke

    DEFF Research Database (Denmark)

    Andersen, Klaus Kaae; Olsen, Tom Skyhøj

    2013-01-01

    Although obesity is associated with excess mortality and morbidity, mortality is lower in obese than in normal weight stroke patients (the obesity paradox). Studies now indicate that obesity is not associated with increased risk of recurrent stroke in the years after first stroke. We studied...... the association between body mass index (BMI) and stroke patient's risk of having a history of previous stroke (recurrent stroke)....

  10. Flavor symmetries and fermion masses

    International Nuclear Information System (INIS)

    Rasin, A.

    1994-04-01

    We introduce several ways in which approximate flavor symmetries act on fermions and which are consistent with observed fermion masses and mixings. Flavor changing interactions mediated by new scalars appear as a consequence of approximate flavor symmetries. We discuss the experimental limits on masses of the new scalars, and show that the masses can easily be of the order of weak scale. Some implications for neutrino physics are also discussed. Such flavor changing interactions would easily erase any primordial baryon asymmetry. We show that this situation can be saved by simply adding a new charged particle with its own asymmetry. The neutrality of the Universe, together with sphaleron processes, then ensures a survival of baryon asymmetry. Several topics on flavor structure of the supersymmetric grand unified theories are discussed. First, we show that the successful predictions for the Kobayashi-Maskawa mixing matrix elements, V ub /V cb = √m u /m c and V td /V ts = √m d /m s , are a consequence of a large class of models, rather than specific properties of a few models. Second, we discuss how the recent observation of the decay β → sγ constrains the parameter space when the ratio of the vacuum expectation values of the two Higgs doublets, tanΒ, is large. Finally, we discuss the flavor structure of proton decay. We observe a surprising enhancement of the branching ratio for the muon mode in SO(10) models compared to the same mode in the SU(5) model

  11. Evaluation of dominant thyroid masses

    International Nuclear Information System (INIS)

    Thomas, C.G. Jr.; Buckwalter, J.A.; Staab, E.V.; Kerr, C.Y.

    1976-01-01

    Controversy exists concerning the management of solitary thyroid nodules because of conflicting information concerning the high clinical incidence of thyroid nodules, the varying incidence of cancer reported in those surgically excised and the infrequency of death from thyroid cancer. During the past several years, a plan for evaluating patients with dominant thyroid masses has evolved. The objective is to avoid unnecessary operations by identifying patients with a high risk of cancer. The criteria which are used are the age and sex of the patient, the duration of the mass, 125 I or /sup 99m/Tc scans, 75 Selenomethionine scans, B-mode ultrasonography and the response of the mass to suppressive therapy. This is a report of the findings in 222 patients who have been studied employing this approach. Thirty percent of the patients were operated upon. Forty percent had neoplasms (well differentiated cancer--28.8 percent, adenoma--12.1 percent), 47.0 percent--nodular goiter, 6.1 percent cysts, and 6.1 percent chronic thyroiditis. The incidence of cancer in the 222 patients was 8.6 percent and adenoma 3.6 percent. Patients at greatest risk of having cancer are those with solid nonfunctioning nodules which fail to regress with suppressive therapy. This study indicates that the approach described above is effective in selecting for surgical excision those individuals at greatest risk of having thyroid cancer

  12. Establishment of peak bone mass.

    Science.gov (United States)

    Mora, Stefano; Gilsanz, Vicente

    2003-03-01

    Among the main areas of progress in osteoporosis research during the last decade or so are the general recognition that this condition, which is the cause of so much pain in the elderly population, has its antecedents in childhood and the identification of the structural basis accounting for much of the differences in bone strength among humans. Nevertheless, current understanding of the bone mineral accrual process is far from complete. The search for genes that regulate bone mass acquisition is ongoing, and current results are not sufficient to identify subjects at risk. However, there is solid evidence that BMD measurements can be helpful for the selection of subjects that presumably would benefit from preventive interventions. The questions regarding the type of preventive interventions, their magnitude, and duration remain unanswered. Carefully designed controlled trials are needed. Nevertheless, previous experience indicates that weight-bearing activity and possibly calcium supplements are beneficial if they are begun during childhood and preferably before the onset of puberty. Modification of unhealthy lifestyles and increments in exercise or calcium assumption are logical interventions that should be implemented to improve bone mass gains in all children and adolescents who are at risk of failing to achieve an optimal peak bone mass.

  13. Charged particle scintillation mass spectrometer

    International Nuclear Information System (INIS)

    Baranov, P.S.; Zhuravlev, E.E.; Nafikov, A.A.; Osadchi , A.I.; Raevskij, V.G.; Smirnov, P.A.; Cherepnya, S.N.; Yanulis, Yu.P.

    1982-01-01

    A scintillation mass-spectrometer for charged particle identification by the measured values of time-of-flight and energy operating on line with the D-116 computer is described. Original time detectors with 100x100x2 mm 3 and 200x2 mm 2 scintillators located on the 1- or 2 m path length are used in the spectrometer. The 200x200x200 mm 3 scintillation unit is used as a E-counter. Time-of-flight spectra of the detected particles on the 2 m path length obtained in spectrometer test in the beam of charged particles escaping from the carbon target at the angle of 130 deg under 1.2 GeV bremsstrahlung beam of the ''Pakhra'' PIAS synchrotron are presented. Proton and deuteron energy spectra as well as mass spectrum of all the particles detected by the spectrometer are given. Mass resolution obtained on the 2 m path length for π-mesons is +-25%, for protons is +-5%, for deuterons is +-3%

  14. Pulmonary mass with renal carcinoma

    International Nuclear Information System (INIS)

    Giraldo Estrada, Horacio

    2003-01-01

    The paper analyzes the case of a 73 year-old patient, masculine sex, obese, with syndrome of obstructive apnoea of the dream, reason why he uses nasal CPAP for 2 at 3 hours in the night for 2 years. It was intervened by renal carcinoma of clear cells at the end of the year 2002. The Rx of thorax preoperative had been informed as normal, but in an abdominal preoperative tomography, the presence of a mass was suggested in the base right lung thorax, reason why Tac is practiced, which demonstrates an irregular nodular image clearly, stuck to the pleura that that suggests unique metastasis of the renal carcinoma. Masses neither mediastinal adenopaties were not evidenced. In the post-operative of their nefrectomy the patient presented dehiscence of the sutures and evisceration, reason why he was re-intervened with primary closing and managed with antibiotics, achieving appropriate scaring. It was programmed for resection of the pulmonary mass. Their evolution and discusses of the case are studied

  15. Mental health in mass gatherings

    Directory of Open Access Journals (Sweden)

    Shahbaz Ali Khan

    2016-01-01

    Full Text Available Background: Hajj pilgrimage, in Saudi Arabia, is one of the world's largest religious mass gatherings. We have similar mass gathering scenarios in India such as the Amarnath Yatra and Kumbh. A unique combination of physical, physiological, and psychological factors makes this pilgrimage a very stressful milieu. We studied the emergence of psychopathology and its determinants, in this adverse environment in mass gathering situation, in Indian pilgrims on Hajj 2016. Materials and Methods: This is a descriptive study analyzing the mental morbidity in 1.36 lakh Indian pilgrims during Hajj 2016, using SPSS software version 19. Results: Totally 182 patients reported psychological problems. Twenty-two patients (12% required admission. Twelve (6.8% pilgrims reported a past history of a mental illness. One hundred and sixty-five (93.2% patients never had any mental symptoms earlier in life. The most common illnesses seen were stress related (45.7% followed by psychosis (9.8%, insomnia (7.3%, and mood disorders (5.6%. The most common symptoms recorded were apprehension (45%, sleep (55%, anxiety (41%, and fear of being lost (27%. Psychotropics were prescribed for 46% of pilgrims. All patients completed their Hajj successfully and returned to India. Conclusions: Cumulative stress causes full spectrum of mental decompensation, and prompt healing is aided by simple nonpharmacological measures including social support and counseling in compatible sociolinguistic milieu.

  16. Mental health in mass gatherings

    Science.gov (United States)

    Khan, Shahbaz Ali; Chauhan, V. S.; Timothy, A.; Kalpana, S.; Khanam, Shagufta

    2016-01-01

    Background: Hajj pilgrimage, in Saudi Arabia, is one of the world's largest religious mass gatherings. We have similar mass gathering scenarios in India such as the Amarnath Yatra and Kumbh. A unique combination of physical, physiological, and psychological factors makes this pilgrimage a very stressful milieu. We studied the emergence of psychopathology and its determinants, in this adverse environment in mass gathering situation, in Indian pilgrims on Hajj 2016. Materials and Methods: This is a descriptive study analyzing the mental morbidity in 1.36 lakh Indian pilgrims during Hajj 2016, using SPSS software version 19. Results: Totally 182 patients reported psychological problems. Twenty-two patients (12%) required admission. Twelve (6.8%) pilgrims reported a past history of a mental illness. One hundred and sixty-five (93.2%) patients never had any mental symptoms earlier in life. The most common illnesses seen were stress related (45.7%) followed by psychosis (9.8%), insomnia (7.3%), and mood disorders (5.6%). The most common symptoms recorded were apprehension (45%), sleep (55%), anxiety (41%), and fear of being lost (27%). Psychotropics were prescribed for 46% of pilgrims. All patients completed their Hajj successfully and returned to India. Conclusions: Cumulative stress causes full spectrum of mental decompensation, and prompt healing is aided by simple nonpharmacological measures including social support and counseling in compatible sociolinguistic milieu. PMID:28659703

  17. GMJ Template 1

    African Journals Online (AJOL)

    USER

    A 39-year-old lady presented in our Ear, Nose and ... The mass was firm, sensitive to touch but did not bleed on contact and appeared to arise from the right lateral nasal wall. The left nasal cavity also had a pale polypoidal mass covered with mucopurulent secretions. The mass was non-sensitive, had no contact bleeding.

  18. Neutrino mass sum rules and symmetries of the mass matrix

    Energy Technology Data Exchange (ETDEWEB)

    Gehrlein, Julia [Karlsruhe Institute of Technology, Institut fuer Theoretische Teilchenphysik, Karlsruhe (Germany); Universidad Autonoma de Madrid, Departamento de Fisica Teorica, Madrid (Spain); Instituto de Fisica Teorica UAM/CSIC, Madrid (Spain); Spinrath, Martin [Karlsruhe Institute of Technology, Institut fuer Theoretische Teilchenphysik, Karlsruhe (Germany); National Center for Theoretical Sciences, Physics Division, Hsinchu (China)

    2017-05-15

    Neutrino mass sum rules have recently gained again more attention as a powerful tool to discriminate and test various flavour models in the near future. A related question which has not yet been discussed fully satisfactorily was the origin of these sum rules and if they are related to any residual or accidental symmetry. We will address this open issue here systematically and find previous statements confirmed. Namely, the sum rules are not related to any enhanced symmetry of the Lagrangian after family symmetry breaking but they are simply the result of a reduction of free parameters due to skillful model building. (orig.)

  19. Position and mass determination of multiple particles using cantilever based mass sensors

    International Nuclear Information System (INIS)

    Dohn, Soeren; Schmid, Silvan; Boisen, Anja; Amiot, Fabien

    2010-01-01

    Resonant microcantilevers are highly sensitive to added masses and have the potential to be used as mass-spectrometers. However, making the detection of individual added masses quantitative requires the position determination for each added mass. We derive expressions relating the position and mass of several added particles to the resonant frequencies of a cantilever, and an identification procedure valid for particles with different masses is proposed. The identification procedure is tested by calculating positions and mass of multiple microparticles with similar mass positioned on individual microcantilevers. Excellent agreement is observed between calculated and measured positions and calculated and theoretical masses.

  20. Black-hole masses of distant quasars

    DEFF Research Database (Denmark)

    Vestergaard, Marianne

    2011-01-01

    A brief overview of the methods commonly used to determine or estimate the black hole mass in quiescent or active galaxies is presented and it is argued that the use of mass-scaling relations is both a reliable and the preferred method to apply to large samples of distant quasars. The method uses...... that the black hole masses are very large, of order 1 to 10 billion solar masses, even at the highest redshifts of 4 to 6. The black holes must build up their mass very fast in the early universe. Yet they do not grow much larger than that: a maximum mass of about 10 billion solar masses is also observed....... Preliminary mass functions of active black holes are presented for several quasar samples, including the Sloan Digital Sky Survey. Finally, common concerns related to the application of the mass scaling relations, especially for high redshift quasars, are briefly discussed....

  1. Zero voltage mass spectrometry probes and systems

    Science.gov (United States)

    Cooks, Robert Graham; Wleklinski, Michael Stanley; Bag, Soumabha; Li, Yafeng

    2017-10-10

    The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous material, and a mass spectrometer (bench-top or miniature mass spectrometer). The system operates without an application of voltage to the probe. In certain embodiments, the probe is oriented such that a distal end faces an inlet of the mass spectrometer. In other embodiments, the distal end of the probe is 5 mm or less from an inlet of the mass spectrometer.

  2. A REVIEW ON MASS SPECTROMETRY DETECTORS

    OpenAIRE

    Khatri Neetu; Gupta Ankit; Taneja Ruchi; Bilandi Ajay; Beniwal Prashant

    2012-01-01

    Mass spectrometry is an analytical technique for "weighing" molecules. Obviously, this is not done with a conventional scale or balance. Instead, mass spectrometry is based upon the principle of the motion of a charged particle that is called an ion, in an electric or magnetic field. The mass to charge ratio (m/z) of the ion affects particles motion. Since the charge of an electron is known, the mass to charge ratio (m/z) is a measurement of mass of an ion. Mass spectrometry research focuses ...

  3. Selling to the moneyed masses.

    Science.gov (United States)

    Nunes, Paul F; Johnson, Brian A; Breene, R Timothy S

    2004-01-01

    Over the past decade, the distribution of household incomes has shifted so much that a much larger proportion of consumers now earn significantly higher-than-average incomes--while still falling short of being truly rich. As a result, what used to be a no-man's-land for new product introductions has in many categories become an extremely profitable "new middle ground." How can marketers capitalize on this new territory? The key, say the authors, is to rethink the positioning and design of offerings and the ways they can be brought to market. Take, for instance, how Procter & Gamble redefined the positioning map for tooth-whitening solutions. A decade ago, dental centers were popularizing expensive bleaching techniques that put the price of a professionally brightened smile in the 400 dollars range. At the low end, consumers also had the choice of whitening toothpastes that cost anywhere from 2 dollars to 8 dollars. P&G wisely positioned itself between the two ends, successfully targeting the new mass market with its 35 dollars Whitestrips. In product categories where it's clear the middle ground has already been populated, it's important for companies to design or redesign offerings to compete. An example is the Polo shirt. How do you sell a man yet another one after he's bought every color he wants? Add some features, and call it a golf shirt. Here, marketers have introduced designs based on the concept of "occasional use" in order to stand out. Finally, companies wishing to reach the "almost rich" can change how they go to market. Perhaps no mass retailer has made a stronger bid for the mass affluent than Target Stores, which has pioneered a focus the company itself characterizes as upscale discount. The strategy has made Target an everyday shopping phenomenon among well-heeled urbanites and prosperous professionals.

  4. Automatic identification of mass spectra

    International Nuclear Information System (INIS)

    Drabloes, F.

    1992-01-01

    Several approaches to preprocessing and comparison of low resolution mass spectra have been evaluated by various test methods related to library search. It is shown that there is a clear correlation between the nature of any contamination of a spectrum, the basic principle of the transformation or distance measure, and the performance of the identification system. The identification of functionality from low resolution spectra has also been evaluated using several classification methods. It is shown that there is an upper limit to the success of this approach, but also that this can be improved significantly by using a very limited amount of additional information. 10 refs

  5. Framework for reactive mass transport

    DEFF Research Database (Denmark)

    Jensen, Mads Mønster; Johannesson, Björn; Geiker, Mette Rica

    2014-01-01

    Reactive transport modeling is applicable for a range of porous materials. Here the modeling framework is focused on cement-based materials, where ion diffusion and migration are described by the Poisson-Nernst-Planck equation system. A two phase vapor/liquid flow model, with a sorption hysteresis...... description is coupled to the system. The mass transport is solved by using the finite element method where the chemical equilibrium is solved explicitly by an operator splitting method. The IPHREEQC library is used as chemical equilibrium solver. The equation system, solved by IPHREEQC, is explained...

  6. Mass chest screening in Luxembourg

    International Nuclear Information System (INIS)

    Kayser, P.

    1987-01-01

    At the present time, all the groups of people examined are not belonging to high risk groups or groups capable of spreading the disease either among colleagues of the profession or users of products or services they are providing. Consequently it will be important to better select in the future the high risk groups. It will be probably necessary to abrogate the examination of future couples. There is presently a project to be adopted in the near future stipulating that mass radiological examinations for prevention of diseases have to be approved by the Ministry of Health, only if they are medically and epidemiologically justified

  7. Agricultural extension and mass media.

    Science.gov (United States)

    Perraton, H

    1983-12-01

    To learn more about the use of the mass media for agricultural extension, the World Bank has considered the efforts of 2 units: INADES-formation in West Africa and the Extension Aids Branch of Malawi. The INADES-formation study focuses on Cameroon but also considers work in Rwanda and the Ivory Coast. Some general conclusions emerge from a comparison of the 2 organizations. Malawi operates an extension service which reaches farmers through extension agents, through farmer training centers, and through mass media. The Extension Aids Branch (EAB) has responsibility for its media work and broadcasts 4 1/2 hours of radio each week. Its 6 regular radio programs include a general program which interviews farmers, a music request program in which the music is interspersed with farming advice, a farming family serial, and a daily broadcast of agricultural news and information. The 17 cinema vans show some agricultural films, made by EAB, some entertainment films, and some government information films from departments other than the ministry of agriculture. EAB also has a well-developed program of research and evaluation of its own work. INADES-formation, the training section of INADES, works towards social and economic development of the population. It teaches peasant farmers and extension agents and does this through running face-to-face seminars, by publishing a magazine, "Agripromo," and through correspondence courses. In 1978-79 INADES-formation enrolled some 4500 farmers and extension agents as students. Both of these organizations work to teach farmers better agriculture techniques, and both were created in response to the fact that agricultural extension agents cannot meet all the farmers in their area. Despite the similarity of objective, there are differences in methods and philosophy. The EAB works in a single country and uses a variety of mass media, with print playing a minor role. INADES-formation is an international and nongovernmental organization and its

  8. Principle of accelerator mass spectrometry

    International Nuclear Information System (INIS)

    Matsuzaki, Hiroyuki

    2007-01-01

    The principle of accelerator mass spectrometry (AMS) is described mainly on technical aspects: hardware construction of AMS, measurement of isotope ratio, sensitivity of measurement (measuring limit), measuring accuracy, and application of data. The content may be summarized as follows: rare isotope (often long-lived radioactive isotope) can be detected by various use of the ion energy obtained by the acceleration of ions, a measurable isotope ratio is one of rare isotope to abundant isotopes, and a measured value of isotope ratio is uncertainty to true one. Such a fact must be kept in mind on the use of AMS data to application research. (M.H.)

  9. Direct measurements of neutrino masses

    Energy Technology Data Exchange (ETDEWEB)

    Holzschuh, E [Zurich Univ. (Switzerland). Inst. fuer Physik

    1996-11-01

    The direct measurements have so far given no indication for a nonzero (positive) mass of any of the three known neutrinos. The experiments measuring the tau and the muon neutrino are good shape. The tritium experiments are in an unfortunate situation. It is unclear to me whether the problems are experimental or theoretical or a combination of both. The electronic final states distribution have been calculated, but the results have never been tested experimentally. The most important question to be answered is about the validity of the sudden approximation. (author) 9 figs., 2 tabs., 16 refs.

  10. Hawaiian hydrogen mass transit system

    International Nuclear Information System (INIS)

    Russell, G.W.; Russell, A.

    1990-01-01

    This paper proposes a joint effort between the scientific and business communities; to create, make and have hydrogen fuel become the primary fuel of the future. Hawaii has abundant, unharnessed renewable resources yet imports almost all of its fuel. Initiating hydrogen production and industrial application in conjunction with a prototype pilot project such as this mass transit system would not only accomplish the joining of science and business but give an environmentally safe energy alternative to the state and people of Hawaii and hopefully the world

  11. Effect of massing on larval growth rate.

    Science.gov (United States)

    Johnson, Aidan P; Wallman, James F

    2014-08-01

    Estimation of minimum postmortem interval commonly relies on predicting the age of blowfly larvae based on their size and an estimate of the temperatures to which they have been exposed throughout their development. The majority of larval growth rate data have been developed using small larval masses in order to avoid excess heat generation. The current study collected growth rate data for larvae at different mass volumes, and assessed the temperature production of these masses, for two forensically important blow fly species, Chrysomya rufifacies and Calliphora vicina. The growth rate of larvae in a small mass, exposed to the higher temperatures equivalent to those experienced by large masses, was also assessed to determine if observed differences were due to the known temperature effects of maggot masses. The results showed that temperature production increased with increasing mass volume, with temperature increases of 11 °C observed in the large Ch. rufifacies masses and increases of 5 °C in the large C. vicina masses. Similarly, the growth rate of the larvae was affected by mass size. The larvae from small masses grown at the higher temperatures experienced by large masses displayed an initial delay in growth, but then grew at a similar rate to those larvae at a constant 23 °C. Since these larvae from masses of equivalent sizes displayed similar patterns of growth rate, despite differing temperatures, and these growth rates differed from larger masses exposed to the same temperatures, it can be concluded that larval growth rate within a mass may be affected by additional factors other than temperature. Overall, this study highlights the importance of understanding the role of massing in larval development and provides initial developmental data for mass sizes of two forensically important blowfly species commonly encountered in Australian forensic casework. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  12. The Use of Gas Chromatography and Mass Spectrometry to Introduce General Chemistry Students to Percent Mass and Atomic Mass Calculations

    Science.gov (United States)

    Pfennig, Brian W.; Schaefer, Amy K.

    2011-01-01

    A general chemistry laboratory experiment is described that introduces students to instrumental analysis using gas chromatography-mass spectrometry (GC-MS), while simultaneously reinforcing the concepts of mass percent and the calculation of atomic mass. Working in small groups, students use the GC to separate and quantify the percent composition…

  13. Building brands without mass media.

    Science.gov (United States)

    Joachimsthaler, E; Aaker, D A

    1997-01-01

    Costs, market fragmentation, and new media channels that let customers bypass advertisements seem to be in league against the old ways of marketing. Relying on mass media campaigns to build strong brands may be a thing of the past. Several companies in Europe, making a virtue of necessity, have come up with alternative brand-building approaches and are blazing a trail in the post-mass-media age. In England, Nestlé's Buitoni brand grew through programs that taught the English how to cook Italian food. The Body Shop garnered loyalty with its support of environmental and social causes. Cadbury funded a theme park tied to its history in the chocolate business. Häagen-Dazs opened posh ice-cream parlors and got itself featured by name on the menus of fine restaurants. Hugo Boss and Swatch backed athletic or cultural events that became associated with their brands. The various campaigns shared characteristics that could serve as guidelines for any company hoping to build a successful brand: senior managers were closely involved with brand-building efforts; the companies recognized the importance of clarifying their core brand identity; and they made sure that all their efforts to gain visibility were tied to that core identity. Studying the methods of companies outside one's own industry and country can be instructive for managers. Pilot testing and the use of a single and continuous measure of brand equity also help managers get the most out of novel approaches in their ever more competitive world.

  14. Mass Extinctions and Supernova Explosions

    Science.gov (United States)

    Korschinek, Gunther

    A nearby supernova (SN) explosion could have negatively influenced life on Earth, maybe even been responsible for mass extinctions. Mass extinction poses a significant extinction of numerous species on Earth, as recorded in the paleontologic, paleoclimatic, and geological record of our planet. Depending on the distance between the Sun and the SN, different types of threats have to be considered, such as ozone depletion on Earth, causing increased exposure to the Sun's ultraviolet radiation or the direct exposure of lethal X-rays. Another indirect effect is cloud formation, induced by cosmic rays in the atmosphere which result in a drop in the Earth's temperature, causing major glaciations of the Earth. The discovery of highly intensive gamma-ray bursts (GRBs), which could be connected to SNe, initiated further discussions on possible life-threatening events in the Earth's history. The probability that GRBs hit the Earth is very low. Nevertheless, a past interaction of Earth with GRBs and/or SNe cannot be excluded and might even have been responsible for past extinction events.

  15. Mass storage technology in networks

    Science.gov (United States)

    Ishii, Katsunori; Takeda, Toru; Itao, Kiyoshi; Kaneko, Reizo

    1990-08-01

    Trends and features of mass storage subsystems in network are surveyed and their key technologies spotlighted. Storage subsystems are becoming increasingly important in new network systems in which communications and data processing are systematically combined. These systems require a new class of high-performance mass-information storage in order to effectively utilize their processing power. The requirements of high transfer rates, high transactional rates and large storage capacities, coupled with high functionality, fault tolerance and flexibility in configuration, are major challenges in storage subsystems. Recent progress in optical disk technology has resulted in improved performance of on-line external memories to optical disk drives, which are competing with mid-range magnetic disks. Optical disks are more effective than magnetic disks in using low-traffic random-access file storing multimedia data that requires large capacity, such as in archive use and in information distribution use by ROM disks. Finally, it demonstrates image coded document file servers for local area network use that employ 130mm rewritable magneto-optical disk subsystems.

  16. Mass Spectrometry Applications for Toxicology.

    Science.gov (United States)

    Mbughuni, Michael M; Jannetto, Paul J; Langman, Loralie J

    2016-12-01

    Toxicology is a multidisciplinary study of poisons, aimed to correlate the quantitative and qualitative relationships between poisons and their physiological and behavioural effects in living systems. Other key aspects of toxicology focus on elucidation of the mechanisms of action of poisons and development of remedies and treatment plans for associated toxic effects. In these endeavours, Mass spectrometry (MS) has become a powerful analytical technique with a wide range of application used in the Toxicological analysis of drugs, poisons, and metabolites of both. To date, MS applications have permeated all fields of toxicology which include; environmental, clinical, and forensic toxicology. While many different analytical applications are used in these fields, MS and its hyphenated applications such as; gas chromatography MS (GC-MS), liquid chromatography MS (LC-MS), inductively coupled plasma ionization MS (ICP-MS), tandem mass spectrometry (MS/MS and MS n ) have emerged as powerful tools used in toxicology laboratories. This review will focus on these hyphenated MS technologies and their applications for toxicology.

  17. Mass Spectrometry Applications for Toxicology

    Science.gov (United States)

    Mbughuni, Michael M.; Jannetto, Paul J.

    2016-01-01

    Toxicology is a multidisciplinary study of poisons, aimed to correlate the quantitative and qualitative relationships between poisons and their physiological and behavioural effects in living systems. Other key aspects of toxicology focus on elucidation of the mechanisms of action of poisons and development of remedies and treatment plans for associated toxic effects. In these endeavours, Mass spectrometry (MS) has become a powerful analytical technique with a wide range of application used in the Toxicological analysis of drugs, poisons, and metabolites of both. To date, MS applications have permeated all fields of toxicology which include; environmental, clinical, and forensic toxicology. While many different analytical applications are used in these fields, MS and its hyphenated applications such as; gas chromatography MS (GC-MS), liquid chromatography MS (LC-MS), inductively coupled plasma ionization MS (ICP-MS), tandem mass spectrometry (MS/MS and MSn) have emerged as powerful tools used in toxicology laboratories. This review will focus on these hyphenated MS technologies and their applications for toxicology. PMID:28149262

  18. Mass-23 nuclei in astrophysics

    International Nuclear Information System (INIS)

    Fraser, P R; Amos, K; Van der Kniff, D; Canton, L; Karataglidis, S; Svenne, J P

    2015-01-01

    The formation of mass-23 nuclei by radiative capture is of great interest in astrophysics. A topical problem associated with these isobars is the so-called 22 Na puzzle of ONe white dwarf novae, where the abundance of 22 Na observed is not as is predicted by current stellar models, indicating there is more to learn about how the distribution of elements in the universe occurred. Another concerns unexplained variations in elements abundance on the surface of aging red giant stars. One method for theoretically studying nuclear scattering is the Multi-Channel Algebraic Scattering (MCAS) formalism. Studies to date have used a simple collective-rotor prescription to model the target states which couple to projectile nucleons. While, in general, the target states considered all belong to the ground state rotor band, for some systems it is necessary to include coupling to states outside of this band. Herein we discuss an extension of MCAS to allow coupling of different strengths between such states and the ground state band. This consideration is essential when studying the scattering of neutrons from 22 Ne, a necessary step in studying the mass-23 nuclei mentioned above. (paper)

  19. Quark mass effects in quark number susceptibilities

    International Nuclear Information System (INIS)

    Graf, Thorben; Petreczky, Peter

    2017-01-01

    The quark degrees of freedom of the QGP with special focus on mass effects are investigated. A next-to-leading-order perturbation theory approach with quark mass dependence is applied and compared to lattice QCD results. (paper)

  20. Numerology of the light particles masses

    International Nuclear Information System (INIS)

    Anoshin, A.I.

    2002-01-01

    The empirical formulae for the masses of light mesons, barions and u-, d-, s-'current' quarks was obtained. The using of calculated 'precise' current quark masses in QCD is given as an example. (author)

  1. Anisotropic dynamic mass density for fluidsolid composites

    KAUST Repository

    Wu, Ying; Mei, Jun; Sheng, Ping

    2012-01-01

    By taking the low frequency limit of multiple-scattering theory, we obtain the dynamic effective mass density of fluidsolid composites with a two-dimensional rectangular lattice structure. The anisotropic mass density can be described by an angle

  2. Pacific Islands Mass Communications; Selected Information Sources.

    Science.gov (United States)

    Richstad, Jim; McMillan, Michael

    1977-01-01

    Presents a bibliography of materials on such area of mass communications in the Pacific Islands as broadcasting, radio and television, cinema, communication research, mass media in education, Honululu Media Council, newspapers and newspapermen, and printing and satellite communication. (JEG)

  3. NICHD Biomedical Mass Spectrometry Core Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The NICHD Biomedical Mass Spectrometry Core Facility was created under the auspices of the Office of the Scientific Director to provide high-end mass-spectrometric...

  4. Mass shifts of charmoniums and electromagnetic signals

    Energy Technology Data Exchange (ETDEWEB)

    Hashimoto, T.; Miyamura, O.; Hirose, K.; Kanki, T.

    1988-04-01

    Mass of psi' below deconfining transition is discussed. It is sensitive to change of string tension. Observations of masses of charmoniums in hot fire ball by electromagnetic probes are considered.

  5. The art of predicting nuclear masses

    International Nuclear Information System (INIS)

    Hirsch, J.G.; Morales, I.; Mendoza-Temis, J.; Frank, A.; Lopez-Vieyra, J.C.; Barea, J.; Pittel, S.; Van Isacker, P.; Velazquez, V.

    2008-01-01

    A review of recent advances in the theoretical analysis of nuclear mass models and their predictive power is presented. After introducing two tests which probe the ability of nuclear mass models to extrapolate, three models are analyzed in detail: the liquid drop model (LDM), the liquid drop model plus empirical shell corrections (LDMM) and the Duflo–Zuker mass formula (DZ). The DZ model is exhibited as the most predictive model. The Garvey–Kelson mass relations are also discussed. It is shown that their fulfillment probes the consistency of the most commonly used mass formulae, and that they can be used in an iterative process to predict nuclear masses in the neighborhood of nuclei with measured masses, offering a simple and reproducible procedure for short range mass predictions. (author)

  6. Know Your Body Mass Index (BMI)

    Science.gov (United States)

    ... Past Issues Special Section Know Your Body Mass Index (BMI) Past Issues / Winter 2007 Table of Contents ... aging, it pays to understand your body mass index (BMI), a measure of body fat based on ...

  7. Atom counting with accelerator mass spectrometry

    International Nuclear Information System (INIS)

    Kutschera, Walter

    1995-01-01

    A brief review of the current status and some recent applications of accelerator mass spectrometry (AMS) are presented. Some connections to resonance ionization mass spectroscopy (RIS) as the alternate atom counting method are discussed

  8. [Mass media consumption in adolescence].

    Science.gov (United States)

    Bercedo Sanz, A; Redondo Figuero, C; Pelayo Alonso, R; Gómez Del Río, Z; Hernández Herrero, M; Cadenas González, N

    2005-12-01

    To describe mass media use in teenagers (television, mobile phones, computers, Internet and video games) and to analyze its influence on teenagers' health and development. We performed a cross sectional study by means of a survey of 884 teenagers aged between 14 and 18 years old who were in the third and fourth years of high school in six towns in Cantabria (Spain) in June 2003. The statistical analysis consisted of uni- and bivariable descriptive statistics. All the teenagers had a television set at home and 24 % of families had four or more television sets. The presence of distinct mass media in teenagers' rooms was 52.5 % for televisions, 57.8 % for computers, 52 % for the Internet and 38.7 % for games consoles. The most frequently found media in teenagers' bedrooms were radio/cassette players and compact disks with 76.8 % and 67.4 %, respectively. Teenagers watched television for an average of 3 hours per day on weekdays and 3.2 hours per day at weekends. They played games consoles for an average of 0.69 hours per day on weekdays (41 min) and an average of 1.09 hours per day (65 min) at weekends and used the Internet on weekdays for an average of 0.83 hours per day (49 min) and an average of 1.15 hours per day (69 min) at weekends. A total of 87.2 % of the teenagers, especially girls, had a mobile phone (91.6 % of girls versus 82.4 % of boys; p chatting and sending e-mails. Sixty-two percent of teenagers had been to a cybercafé and 40.8 % has visited a pornographic web site, especially boys (33.1 % of boys versus 7.7 % of girls; p video console, especially boys (87 % of boys versus 57.2 % of girls; p video games with shooting, fights, sports and driving, while girls preferred adventure video games. Nearly a quarter (22.2 %) spent money on video games and cybercafés (an average of 27.06 3 a month in boys and 16.81 3 a month in girls) with no significant differences between sexes. Society as a whole and especially health professionals should increase health

  9. MPAI (mass probes aided ionization) method for total analysis of biomolecules by mass spectrometry.

    Science.gov (United States)

    Honda, Aki; Hayashi, Shinichiro; Hifumi, Hiroki; Honma, Yuya; Tanji, Noriyuki; Iwasawa, Naoko; Suzuki, Yoshio; Suzuki, Koji

    2007-01-01

    We have designed and synthesized various mass probes, which enable us to effectively ionize various molecules to be detected with mass spectrometry. We call the ionization method using mass probes the "MPAI (mass probes aided ionization)" method. We aim at the sensitive detection of various biological molecules, and also the detection of bio-molecules by a single mass spectrometry serially without changing the mechanical settings. Here, we review mass probes for small molecules with various functional groups and mass probes for proteins. Further, we introduce newly developed mass probes for proteins for highly sensitive detection.

  10. Critical assessment of nuclear mass models

    International Nuclear Information System (INIS)

    Moeller, P.; Nix, J.R.

    1992-01-01

    Some of the physical assumptions underlying various nuclear mass models are discussed. The ability of different mass models to predict new masses that were not taken into account when the models were formulated and their parameters determined is analyzed. The models are also compared with respect to their ability to describe nuclear-structure properties in general. The analysis suggests future directions for mass-model development

  11. On the Origin of Elementary Particle Masses

    OpenAIRE

    Hansson, Johan

    2012-01-01

    The oldest enigma in fundamental particle physics is: Where do the observed masses of elementary particles come from? Inspired by observation of the empirical particle mass spectrum we propose that the masses of elementary parti cles arise solely due to the self-interaction of the fields associated with a particle. We thus assume that the mass is proportional to the strength of the interaction of th e field with itself. A simple application of this idea to the fermi...

  12. Neutrino mass hierarchy and matter effects

    OpenAIRE

    Smirnov, Alexei Yu.

    2013-01-01

    Matter effects modify the mixing and the effective masses of neutrinos in a way which depends on the neutrino mass hierarchy. Consequently, for normal and inverted hierarchies the oscillations and flavor conversion results are different. Sensitivity to the mass hierarchy appears whenever the matter effects on the 1-3 mixing and mass splitting become substantial. This happens in supernovae in wide energy range and in the matter of the Earth. The Earth density profile is a multi-layer medium wh...

  13. Evaluation of Virtual Refrigerant Mass Flow Sensors

    OpenAIRE

    Kim, Woohyun; Braun, James E.

    2012-01-01

    Refrigerant mass flow rate is an important measurement for monitoring equipment performance and enabling fault detection and diagnostics. However, a traditional mass flow meter is expensive to purchase and install. A virtual refrigerant mass flow sensor (VRMF) uses a mathematical model to estimate flow rate using low-cost measurements and can potentially be implemented at low cost. This study evaluates three VRMFs for estimating refrigerant mass flow rate. The first model uses a compressor ma...

  14. 14 CFR 27.659 - Mass balance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Mass balance. 27.659 Section 27.659... STANDARDS: NORMAL CATEGORY ROTORCRAFT Design and Construction Rotors § 27.659 Mass balance. (a) The rotors... flutter at any speed up to the maximum forward speed. (b) The structural integrity of the mass balance...

  15. 14 CFR 29.659 - Mass balance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Mass balance. 29.659 Section 29.659... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Design and Construction Rotors § 29.659 Mass balance. (a) The rotor... flutter at any speed up to the maximum forward speed. (b) The structural integrity of the mass balance...

  16. 14 CFR 23.659 - Mass balance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Mass balance. 23.659 Section 23.659 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Surfaces § 23.659 Mass balance. The supporting structure and the attachment of concentrated mass balance...

  17. The mass of the Milky Way

    NARCIS (Netherlands)

    Kuijken, K; Bender, T; Renzini, A

    2003-01-01

    The Mass distribution of the Galaxy is reasonably well understood. Out to a radius of at least 200kpc, the enclosed mass increases roughly linearly with radius at about 10(10)M(circle dot) per kpc. The inner mass distribution is inconsistent with what we know to be present in stars and gas. Recent

  18. Nutritional interventions to preserve skeletal muscle mass

    NARCIS (Netherlands)

    Backx, Evelien M.P.

    2016-01-01

    Muscle mass is the main predictor for muscle strength and physical function. The amount of muscle mass can decline rapidly during periods of reduced physical activity or during periods of energy intake restriction. For athletes, it is important to maintain muscle mass, since the loss of muscle is

  19. Parsimonious Charge Deconvolution for Native Mass Spectrometry

    Science.gov (United States)

    2018-01-01

    Charge deconvolution infers the mass from mass over charge (m/z) measurements in electrospray ionization mass spectra. When applied over a wide input m/z or broad target mass range, charge-deconvolution algorithms can produce artifacts, such as false masses at one-half or one-third of the correct mass. Indeed, a maximum entropy term in the objective function of MaxEnt, the most commonly used charge deconvolution algorithm, favors a deconvolved spectrum with many peaks over one with fewer peaks. Here we describe a new “parsimonious” charge deconvolution algorithm that produces fewer artifacts. The algorithm is especially well-suited to high-resolution native mass spectrometry of intact glycoproteins and protein complexes. Deconvolution of native mass spectra poses special challenges due to salt and small molecule adducts, multimers, wide mass ranges, and fewer and lower charge states. We demonstrate the performance of the new deconvolution algorithm on a range of samples. On the heavily glycosylated plasma properdin glycoprotein, the new algorithm could deconvolve monomer and dimer simultaneously and, when focused on the m/z range of the monomer, gave accurate and interpretable masses for glycoforms that had previously been analyzed manually using m/z peaks rather than deconvolved masses. On therapeutic antibodies, the new algorithm facilitated the analysis of extensions, truncations, and Fab glycosylation. The algorithm facilitates the use of native mass spectrometry for the qualitative and quantitative analysis of protein and protein assemblies. PMID:29376659

  20. Data recording and processing in mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    McKown, H. [International Atomic Energy Agency, Vienna (Austria)

    1978-12-15

    When a mass spectrometer is going to be obtained, it must be specified to do a particular task. It follows that the data recording system must be designed to work satisfactorily with hardware that produces the ion current or currents. The author describes two systems: the AVCO mass spectrometer and the tandem mass spectrometer.