Source selection for cluster weak lensing measurements in the Hyper Suprime-Cam survey

Science.gov (United States)

Medezinski, Elinor; Oguri, Masamune; Nishizawa, Atsushi J.; Speagle, Joshua S.; Miyatake, Hironao; Umetsu, Keiichi; Leauthaud, Alexie; Murata, Ryoma; Mandelbaum, Rachel; Sifón, Cristóbal; Strauss, Michael A.; Huang, Song; Simet, Melanie; Okabe, Nobuhiro; Tanaka, Masayuki; Komiyama, Yutaka

2018-03-01

We present optimized source galaxy selection schemes for measuring cluster weak lensing (WL) mass profiles unaffected by cluster member dilution from the Subaru Hyper Suprime-Cam Strategic Survey Program (HSC-SSP). The ongoing HSC-SSP survey will uncover thousands of galaxy clusters to z ≲ 1.5. In deriving cluster masses via WL, a critical source of systematics is contamination and dilution of the lensing signal by cluster members, and by foreground galaxies whose photometric redshifts are biased. Using the first-year CAMIRA catalog of ˜900 clusters with richness larger than 20 found in ˜140 deg2 of HSC-SSP data, we devise and compare several source selection methods, including selection in color-color space (CC-cut), and selection of robust photometric redshifts by applying constraints on their cumulative probability distribution function (P-cut). We examine the dependence of the contamination on the chosen limits adopted for each method. Using the proper limits, these methods give mass profiles with minimal dilution in agreement with one another. We find that not adopting either the CC-cut or P-cut methods results in an underestimation of the total cluster mass (13% ± 4%) and the concentration of the profile (24% ± 11%). The level of cluster contamination can reach as high as ˜10% at R ≈ 0.24 Mpc/h for low-z clusters without cuts, while employing either the P-cut or CC-cut results in cluster contamination consistent with zero to within the 0.5% uncertainties. Our robust methods yield a ˜60 σ detection of the stacked CAMIRA surface mass density profile, with a mean mass of M200c = [1.67 ± 0.05(stat)] × 1014 M⊙/h.

Great Optically Luminous Dropout Research Using Subaru HSC (GOLDRUSH). I. UV luminosity functions at z ˜ 4-7 derived with the half-million dropouts on the 100 deg2 sky

Science.gov (United States)

Ono, Yoshiaki; Ouchi, Masami; Harikane, Yuichi; Toshikawa, Jun; Rauch, Michael; Yuma, Suraphong; Sawicki, Marcin; Shibuya, Takatoshi; Shimasaku, Kazuhiro; Oguri, Masamune; Willott, Chris; Akhlaghi, Mohammad; Akiyama, Masayuki; Coupon, Jean; Kashikawa, Nobunari; Komiyama, Yutaka; Konno, Akira; Lin, Lihwai; Matsuoka, Yoshiki; Miyazaki, Satoshi; Nagao, Tohru; Nakajima, Kimihiko; Silverman, John; Tanaka, Masayuki; Taniguchi, Yoshiaki; Wang, Shiang-Yu

2018-01-01

We study the UV luminosity functions (LFs) at z ˜ 4, 5, 6, and 7 based on the deep large-area optical images taken by the Hyper Suprime-Cam (HSC) Subaru Strategic Program (SSP). On the 100 deg2 sky of the HSC SSP data available to date, we take enormous samples consisting of a total of 579565 dropout candidates at z ˜ 4-7 by the standard color selection technique, 358 out of which are spectroscopically confirmed by our follow-up spectroscopy and other studies. We obtain UV LFs at z ˜ 4-7 that span a very wide UV luminosity range of ˜0.002-100 L_UV^\\ast (-26 2 σ significance, and require either double power-law functions or modified Schechter functions that consider a magnification bias due to gravitational lensing.

SPLASH-SXDF Multi-wavelength Photometric Catalog

Science.gov (United States)

Mehta, Vihang; Scarlata, Claudia; Capak, Peter; Davidzon, Iary; Faisst, Andreas; Hsieh, Bau Ching; Ilbert, Olivier; Jarvis, Matt; Laigle, Clotilde; Phillips, John; Silverman, John; Strauss, Michael A.; Tanaka, Masayuki; Bowler, Rebecca; Coupon, Jean; Foucaud, Sébastien; Hemmati, Shoubaneh; Masters, Daniel; McCracken, Henry Joy; Mobasher, Bahram; Ouchi, Masami; Shibuya, Takatoshi; Wang, Wei-Hao

2018-04-01

We present a multi-wavelength catalog in the Subaru/XMM-Newton Deep Field (SXDF) as part of the Spitzer Large Area Survey with Hyper-Suprime-Cam (SPLASH). We include the newly acquired optical data from the Hyper-Suprime-Cam Subaru Strategic Program, accompanied by IRAC coverage from the SPLASH survey. All available optical and near-infrared data is homogenized and resampled on a common astrometric reference frame. Source detection is done using a multi-wavelength detection image including the u-band to recover the bluest objects. We measure multi-wavelength photometry and compute photometric redshifts as well as physical properties for ∼1.17 million objects over ∼4.2 deg2, with ∼800,000 objects in the 2.4 deg2 HSC-Ultra-Deep coverage. Using the available spectroscopic redshifts from various surveys over the range of 0 fraction of 3.2%. The SPLASH-SXDF catalog is a valuable, publicly available resource, perfectly suited for studying galaxies in the early universe and tracing their evolution through cosmic time.

Machine-learning-based real-bogus system for the HSC-SSP moving object detection pipeline

Science.gov (United States)

Lin, Hsing-Wen; Chen, Ying-Tung; Wang, Jen-Hung; Wang, Shiang-Yu; Yoshida, Fumi; Ip, Wing-Huen; Miyazaki, Satoshi; Terai, Tsuyoshi

2018-01-01

Machine-learning techniques are widely applied in many modern optical sky surveys, e.g., Pan-STARRS1, PTF/iPTF, and the Subaru/Hyper Suprime-Cam survey, to reduce human intervention in data verification. In this study, we have established a machine-learning-based real-bogus system to reject false detections in the Subaru/Hyper-Suprime-Cam Strategic Survey Program (HSC-SSP) source catalog. Therefore, the HSC-SSP moving object detection pipeline can operate more effectively due to the reduction of false positives. To train the real-bogus system, we use stationary sources as the real training set and "flagged" data as the bogus set. The training set contains 47 features, most of which are photometric measurements and shape moments generated from the HSC image reduction pipeline (hscPipe). Our system can reach a true positive rate (tpr) ˜96% with a false positive rate (fpr) ˜1% or tpr ˜99% at fpr ˜5%. Therefore, we conclude that stationary sources are decent real training samples, and using photometry measurements and shape moments can reject false positives effectively.

Subaru Weak Lensing Measurements of Four Strong Lensing Clusters: Are Lensing Clusters Over-Concentrated?

Energy Technology Data Exchange (ETDEWEB)

Oguri, Masamune; Hennawi, Joseph F.; Gladders, Michael D.; Dahle, Haakon; Natarajan, Priyamvada; Dalal, Neal; Koester, Benjamin P.; Sharon, Keren; Bayliss, Matthew

2009-01-29

We derive radial mass profiles of four strong lensing selected clusters which show prominent giant arcs (Abell 1703, SDSS J1446+3032, SDSS J1531+3414, and SDSS J2111-0115), by combining detailed strong lens modeling with weak lensing shear measured from deep Subaru Suprime-cam images. Weak lensing signals are detected at high significance for all four clusters, whose redshifts range from z = 0.28 to 0.64. We demonstrate that adding strong lensing information with known arc redshifts significantly improves constraints on the mass density profile, compared to those obtained from weak lensing alone. While the mass profiles are well fitted by the universal form predicted in N-body simulations of the {Lambda}-dominated cold dark matter model, all four clusters appear to be slightly more centrally concentrated (the concentration parameters c{sub vir} {approx} 8) than theoretical predictions, even after accounting for the bias toward higher concentrations inherent in lensing selected samples. Our results are consistent with previous studies which similarly detected a concentration excess, and increases the total number of clusters studied with the combined strong and weak lensing technique to ten. Combining our sample with previous work, we find that clusters with larger Einstein radii are more anomalously concentrated. We also present a detailed model of the lensing cluster Abell 1703 with constraints from multiple image families, and find the dark matter inner density profile to be cuspy with the slope consistent with -1, in agreement with expectations.

The stellar content of the isolated transition dwarf galaxy DDO210

NARCIS (Netherlands)

McConnachie, Alan W.; Arimoto, Nobuo; Irwin, Mike; Tolstoy, Eline

2006-01-01

We use Subaru Suprime-Cam and VLT FORS1 photometry of the dwarf galaxy DDO210 to study the global stellar content and structural properties of a transition-type galaxy (with properties intermediate between dwarf irregular and dwarf spheroidal systems). This galaxy is sufficiently isolated that tidal

NGC 3628-UCD1:A possible $ω$ Cen Analog Embedded in a Stellar Stream

OpenAIRE

Jennings, Zachary G.; Romanowsky, Aaron J.; Brodie, Jean P.; Janz, Joachim; Norris, Mark A.; Forbes, Duncan A.; Martinez-Delgado, David; Fagioli, Martina; Penny, Samantha J.

2015-01-01

Using Subaru/Suprime-Cam wide-field imaging and both Keck/ESI and LBT/MODS spectroscopy, we identify and characterize a compact star cluster, which we term NGC 3628-UCD1, embedded in a stellar stream around the spiral galaxy NGC 3628. The size and luminosity of UCD1 are similar to $\\omega$ Cen, the most luminous Milky Way globular cluster, which has long been suspected to be the stripped remnant of an accreted dwarf galaxy. The object has a magnitude of $i=19.3$ mag (${\\rm L}_{\\rm i}=1.4\\time...

A medium-deep Chandra and Subaru survey of the 13-h XMM/ROSAT deep survey area

Science.gov (United States)

McHardy, I. M.; Gunn, K. F.; Newsam, A. M.; Mason, K. O.; Page, M. J.; Takata, T.; Sekiguchi, K.; Sasseen, T.; Cordova, F.; Jones, L. R.; Loaring, N.

2003-07-01

We present the results of a Chandra ACIS-I survey of a high-latitude region at 13 h +38° which was earlier observed with ROSAT and which has recently been observed by XMM-Newton for 200 ks. XMM-Newton will provide good-quality X-ray spectra for over 200 sources with fluxes around the knee of the log N/ log S, which are responsible for the bulk of the X-ray background. The main aim of the Chandra observations is to provide arcsecond, or better, positions, and hence reliable identifications, for the XMM-Newton sources. The ACIS-I observations were arranged in a mosaic of four 30-ks pointings, covering almost all of the 15-arcmin radius XMM-Newton/ROSAT field. We detect 214 Chandra sources above a Cash likelihood statistic of 25, which approximates to 5σ significance, to a limiting flux of ~1.3 × 10-15 erg cm-2 s-1 (0.5-7 keV). Optical counterparts are derived from a Subaru SuprimeCam image reaching to R~ 27. The very large majority of the Chandra sources have an optical counterpart, with the distribution peaking at 23 high LX/Lopt ratios, implying absorption at moderate redshift. Comparison with the earlier ROSAT survey shows that the accuracy of the ROSAT positions agrees very well with the predictions from simulations by McHardy et al. and that the large majority of the identifications were correct.

Galaxy interactions trigger rapid black hole growth: An unprecedented view from the Hyper Suprime-Cam survey

Science.gov (United States)

Goulding, Andy D.; Greene, Jenny E.; Bezanson, Rachel; Greco, Johnny; Johnson, Sean; Leauthaud, Alexie; Matsuoka, Yoshiki; Medezinski, Elinor; Price-Whelan, Adrian M.

2018-01-01

Collisions and interactions between gas-rich galaxies are thought to be pivotal stages in their formation and evolution, causing the rapid production of new stars, and possibly serving as a mechanism for fueling supermassive black holes (BHs). Harnessing the exquisite spatial resolution (˜0{^''.}5) afforded by the first ˜170 deg2 of the Hyper Suprime-Cam (HSC) survey, we present our new constraints on the importance of galaxy-galaxy major mergers (1 : 4) in growing BHs throughout the last ˜8 Gyr. Utilizing mid-infrared observations in the WISE all-sky survey, we robustly select active galactic nuclei (AGN) and mass-matched control galaxy samples, totaling ˜140000 spectroscopically confirmed systems at i based on our comparison of AGN fractions in mass-matched samples, we determine that the most luminous AGN population (LAGN ≳ 1045 erg s-1) systematically reside in merging systems over non-interacting galaxies. Our findings show that galaxy-galaxy interactions do, on average, trigger luminous AGN activity substantially more often than in secularly evolving non-interacting galaxies, and we further suggest that the BH growth rate may be closely tied to the dynamical time of the merger system.

Individual stellar haloes of massive galaxies measured to 100 kpc at 0.3 < z < 0.5 using Hyper Suprime-Cam

Science.gov (United States)

Huang, Song; Leauthaud, Alexie; Greene, Jenny E.; Bundy, Kevin; Lin, Yen-Ting; Tanaka, Masayuki; Miyazaki, Satoshi; Komiyama, Yutaka

2018-04-01

Massive galaxies display extended light profiles that can reach several hundreds of kiloparsecs. We use data from the Hyper Suprime-Cam (HSC) survey that is simultaneously wide (˜100 deg2) and deep (>28.5 mag arcsec-2 in i band) to study the stellar haloes of a sample of ˜7000 massive galaxies at z ˜ 0.4. The depth of the HSC data enables us to measure surface mass density profiles to 100 kpc for individual galaxies without stacking. As in previous work, we find that more massive galaxies exhibit more extended outer profiles than smaller galaxies. When this extended light is not properly accounted for (because of shallow imaging and/or inadequate profile modelling), the derived stellar mass function can be significantly underestimated at the high-mass end. Across our sample, the ellipticity of outer light profile increases substantially with radius. We show for the first time that these ellipticity gradients steepen dramatically as a function of galaxy mass, but we detect no mass dependence in outer colour gradients. Our results support the two-phase formation scenario for massive galaxies in which outer envelopes are built up at a later time from a series of merging events. We provide surface mass density profiles in a convenient tabulated format to facilitate comparisons with predictions from numerical simulations of galaxy formation.

STAR FORMATION AT 4 < z < 6 FROM THE SPITZER LARGE AREA SURVEY WITH HYPER-SUPRIME-CAM (SPLASH)

Energy Technology Data Exchange (ETDEWEB)

Steinhardt, Charles L.; Capak, Peter; Masters, Dan; Petric, Andreea [Caltech, 1200 E. California Blvd., Pasadena, CA 91125 (United States); Speagle, Josh S.; Silverman, John D. [Kavli IPMU, University of Tokyo, Kashiwanoha 5-1-5, Kashiwa-shi, Chiba 277-8583 (Japan); Carollo, Marcella [ETH Zurich, Wolfgang-Pauli-Strasse 27, 8093 Zurich (Switzerland); Dunlop, James [Institute for Astronomy, University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Hashimoto, Yasuhiro [National Taiwan Normal University, No. 88, Sec. 4, Tingzhou Rd., Taipei 11677, Taiwan R.O.C. (China); Hsieh, Bau-Ching; Lin, Lihwai; Lin, Yen-Ting [ASIAA Sinica, AS/NTU. No. 1, Sec. 4, Roosevelt Rd., Taipei 10617, Taiwan, R.O.C. (China); Ilbert, Olivier; Le Fevre, Olivier [Laboratoire d' Astrophysique de Marseille, 38 rue Frederic Joliot Curie, F-13388 Marseille (France); Le Floc' h, Emeric [Service d' Astrophysique, CEA-Saclay, Orme des Merisiers, Bat. 709, F-91191 Gif-sur-Yvette (France); Lee, Nicholas; Sanders, Dave [Institute for Astronomy, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); McCracken, Henry J. [Institut d' Astrophysique de Paris, 98 bis boulevard Arago, F-75014 Paris (France); Nagao, Tohru [Kyoto University, Kitashirakawa-Oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Salvato, Mara [Max Planck Institute for Extraterrestrial Physics (MPE), Giessenbachstr. 1, D-85748 Garching (Germany); and others

2014-08-20

Using the first 50% of data collected for the Spitzer Large Area Survey with Hyper-Suprime-Cam observations on the 1.8 deg{sup 2} Cosmological Evolution Survey we estimate the masses and star formation rates of 3398 M {sub *} > 10{sup 10} M {sub ☉} star-forming galaxies at 4 < z < 6 with a substantial population up to M {sub *} ≳ 10{sup 11.5} M {sub ☉}. We find that the strong correlation between stellar mass and star formation rate seen at lower redshift (the ''main sequence'' of star-forming galaxies) extends to z ∼ 6. The observed relation and scatter is consistent with a continued increase in star formation rate at fixed mass in line with extrapolations from lower-redshift observations. It is difficult to explain this continued correlation, especially for the most massive systems, unless the most massive galaxies are forming stars near their Eddington-limited rate from their first collapse. Furthermore, we find no evidence for moderate quenching at higher masses, indicating quenching either has not occurred prior to z ∼ 6 or else occurs rapidly, so that few galaxies are visible in transition between star-forming and quenched.

THE SUBARU HIGH-z QUASAR SURVEY: DISCOVERY OF FAINT z ∼ 6 QUASARS

International Nuclear Information System (INIS)

Kashikawa, Nobunari; Furusawa, Hisanori; Niino, Yuu; Ishizaki, Yoshifumi; Onoue, Masafusa; Toshikawa, Jun; Ishikawa, Shogo; Willott, Chris J.; Im, Myungshin; Shimasaku, Kazuhiro; Ouchi, Masami; Hibon, Pascale

2015-01-01

We present the discovery of one or two extremely faint z ∼ 6 quasars in 6.5 deg 2 utilizing a unique capability of the wide-field imaging of the Subaru/Suprime-Cam. The quasar selection was made in (i'-z B ) and (z B -z R ) colors, where z B and z R are bandpasses with central wavelengths of 8842 Å and 9841 Å, respectively. The color selection can effectively isolate quasars at z ∼ 6 from M/L/T dwarfs without the J-band photometry down to z R < 24.0, which is 3.5 mag deeper than the Sloan Digital Sky Survey (SDSS). We have selected 17 promising quasar candidates. The follow-up spectroscopy for seven targets identified one apparent quasar at z = 6.156 with M 1450 = –23.10. We also identified one possible quasar at z = 6.041 with a faint continuum of M 1450 = –22.58 and a narrow Lyα emission with HWHM =427 km s –1 , which cannot be distinguished from Lyman α emitters. We derive the quasar luminosity function at z ∼ 6 by combining our faint quasar sample with the bright quasar samples by SDSS and CFHQS. Including our data points invokes a higher number density in the faintest bin of the quasar luminosity function than the previous estimate employed. This suggests a steeper faint-end slope than lower z, though it is yet uncertain based on a small number of spectroscopically identified faint quasars, and several quasar candidates still remain to be diagnosed. The steepening of the quasar luminosity function at the faint end does increase the expected emission rate of the ionizing photon; however, it only changes by a factor of approximately two to six. This was found to still be insufficient for the required photon budget of reionization at z ∼ 6

SUBARU WEAK-LENSING STUDY OF A2163: BIMODAL MASS STRUCTURE

International Nuclear Information System (INIS)

Okabe, N.; Bourdin, H.; Mazzotta, P.; Maurogordato, S.

2011-01-01

We present a weak-lensing analysis of the merging cluster A2163 using Subaru/Suprime-Cam and CFHT/Mega-Cam data and discuss the dynamics of this cluster merger, based on complementary weak-lensing, X-ray, and optical spectroscopic data sets. From two-dimensional multi-component weak-lensing analysis, we reveal that the cluster mass distribution is well described by three main components including the two-component main cluster A2163-A with mass ratio 1:8, and its cluster satellite A2163-B. The bimodal mass distribution in A2163-A is similar to the galaxy density distribution, but appears as spatially segregated from the brightest X-ray emitting gas region. We discuss the possible origins of this gas-dark-matter offset and suggest the gas core of the A2163-A subcluster has been stripped away by ram pressure from its dark matter component. The survival of this gas core from the tidal forces exerted by the main cluster lets us infer a subcluster accretion with a non-zero impact parameter. Dominated by the most massive component of A2163-A, the mass distribution of A2163 is well described by a universal Navarro-Frenk-White profile as shown by a one-dimensional tangential shear analysis, while the singular-isothermal sphere profile is strongly ruled out. Comparing this cluster mass profile with profiles derived assuming intracluster medium hydrostatic equilibrium (H.E.) in two opposite regions of the cluster atmosphere has allowed us to confirm the prediction of a departure from H.E. in the eastern cluster side, presumably due to shock heating. Yielding a cluster mass estimate of M 500 = 11.18 +1.64 –1.46 × 10 14 h –1 M ☉ , our mass profile confirms the exceptionally high mass of A2163, consistent with previous analyses relying on the cluster dynamical analysis and Y X mass proxy.

Using Gaia as an Astrometric Tool for Deep Ground-based Surveys

Science.gov (United States)

Casetti-Dinescu, Dana I.; Girard, Terrence M.; Schriefer, Michael

2018-04-01

Gaia DR1 positions are used to astrometrically calibrate three epochs' worth of Subaru SuprimeCam images in the fields of globular cluster NGC 2419 and the Sextans dwarf spheroidal galaxy. Distortion-correction ``maps'' are constructed from a combination of offset dithers and reference to Gaia DR1. These are used to derive absolute proper motions in the field of NGC 2419. Notably, we identify the photometrically-detected Monoceros structure in the foreground of NGC 2419 as a kinematically-cold population of stars, distinct from Galactic-field stars. This project demonstrates the feasibility of combining Gaia with deep, ground-based surveys, thus extending high-quality astrometry to magnitudes beyond the limits of Gaia.

The stellar content of the isolated transition dwarf galaxy DDO210

OpenAIRE

McConnachie, Alan W.; Arimoto, Nobuo; Irwin, Mike; Tolstoy, Eline

2006-01-01

We use Subaru Suprime-Cam and VLT FORS1 photometry of the dwarf galaxy DDO210 to study the global stellar content and structural properties of a transition-type galaxy (with properties intermediate between dwarf irregular and dwarf spheroidal systems). This galaxy is sufficiently isolated that tidal interactions are not likely to have affected its evolution in any way. The colour-magnitude diagrams of DDO210 show a red giant branch (RGB) population (with an RGB bump), a bright asymptotic gian...

The bright-star masks for the HSC-SSP survey

Science.gov (United States)

Coupon, Jean; Czakon, Nicole; Bosch, James; Komiyama, Yutaka; Medezinski, Elinor; Miyazaki, Satoshi; Oguri, Masamune

2018-01-01

We present the procedure to build and validate the bright-star masks for the Hyper-Suprime-Cam Strategic Subaru Proposal (HSC-SSP) survey. To identify and mask the saturated stars in the full HSC-SSP footprint, we rely on the Gaia and Tycho-2 star catalogues. We first assemble a pure star catalogue down to GGaia SSP, finding that our star catalogue is 99.2% pure down to GGaia SSP observations at "ftp://obsftp.unige.ch/pub/coupon/brightStarMasks/HSC-SSP/".

VizieR Online Data Catalog: Colour and spectral index from the SLUGGS survey (Usher+, 2015)

Science.gov (United States)

Usher, C.; Forbes, D. A.; Brodie, J. P.; Romanowsky, A. J.; Strader, J.; Conroy, C.; Foster, C.; Pastorello, N.; Pota, V.; Arnold, J. A.

2017-10-01

The SLUGGS survey is an ongoing study of 25 massive, nearby, early-type galaxies and their GC systems using Keck DEIMOS spectroscopy and wide-field imaging from Suprime-Cam (Miyazaki et al. 2002, PASJ, 54, 833) on the Subaru telescope. The spectra were all observed with DEIMOS in multislit mode between 2006 and 2013 with the primary aim of measuring GC radial velocities. Exposure times averaged two hours per slit mask. All observations used a central wavelength of 7800 Å, the 1200 line/mm grating and 1 arcsec slits. This setup yields a resolution of Δλ~1.5 Å and covers the Na I doublet to CaT wavelength region. In roughly half of the slits, Hα is also covered. (3 data files).

A DOZEN NEW GALAXIES CAUGHT IN THE ACT: GAS STRIPPING AND EXTENDED EMISSION LINE REGIONS IN THE COMA CLUSTER

International Nuclear Information System (INIS)

Yagi, Masafumi; Komiyama, Yutaka; Kashikawa, Nobunari; Yoshida, Michitoshi; Furusawa, Hisanori; Okamura, Sadanori; Graham, Alister W.; Miller, Neal A.; Carter, David; Mobasher, Bahram; Jogee, Shardha

2010-01-01

We present images of extended Hα clouds associated with 14 member galaxies in the Coma cluster obtained from deep narrowband imaging observations with the Suprime-Cam at the Subaru Telescope. The parent galaxies of the extended Hα clouds are distributed farther than 0.2 Mpc from the peak of the X-ray emission of the cluster. Most of the galaxies are bluer than g - r ∼ 0.5 and they account for 57% of the blue (g - r < 0.5) bright (r < 17.8 mag) galaxies in the central region of the Coma cluster. They reside near the red- and blueshifted edges of the radial velocity distribution of Coma cluster member galaxies. Our findings suggest that most of the parent galaxies were recently captured by the Coma cluster potential and are now infalling toward the cluster center with their disk gas being stripped off and producing the observed Hα clouds.

Comparative evaluation of RetCam vs. gonioscopy images in congenital glaucoma.

Science.gov (United States)

Azad, Raj V; Chandra, Parijat; Chandra, Anuradha; Gupta, Aparna; Gupta, Viney; Sihota, Ramanjit

2014-02-01

To compare clarity, exposure and quality of anterior chamber angle visualization in congenital glaucoma patients, using RetCam and indirect gonioscopy images. Cross-sectional study Participants. Congenital glaucoma patients over age of 5 years. A prospective consecutive pilot study was done in congenital glaucoma patients who were older than 5 years. Methods used are indirect gonioscopy and RetCam imaging. Clarity of the image, extent of angle visible and details of angle structures seen were graded for both methods, on digitally recorded images, in each eye, by two masked observers. Image clarity, interobserver agreement. 40 eyes of 25 congenital glaucoma patients were studied. RetCam image had excellent clarity in 77.5% of patients versus 47.5% by gonioscopy. The extent of angle seen was similar by both methods. Agreement between RetCam and gonioscopy images regarding details of angle structures was 72.50% by observer 1 and 65.00% by observer 2. There was good agreement between RetCam and indirect gonioscopy images in detecting angle structures of congenital glaucoma patients. However, RetCam provided greater clarity, with better quality, and higher magnification images. RetCam can be a useful alternative to gonioscopy in infants and small children without the need for general anesthesia.

Comparative evaluation of RetCam vs. gonioscopy images in congenital glaucoma

Directory of Open Access Journals (Sweden)

Raj V Azad

2014-01-01

Full Text Available Purpose: To compare clarity, exposure and quality of anterior chamber angle visualization in congenital glaucoma patients, using RetCam and indirect gonioscopy images. Design: Cross-sectional study Participants. Congenital glaucoma patients over age of 5 years. Materials and Methods: A prospective consecutive pilot study was done in congenital glaucoma patients who were older than 5 years. Methods used are indirect gonioscopy and RetCam imaging. Clarity of the image, extent of angle visible and details of angle structures seen were graded for both methods, on digitally recorded images, in each eye, by two masked observers. Outcome Measures: Image clarity, interobserver agreement. Results: 40 eyes of 25 congenital glaucoma patients were studied. RetCam image had excellent clarity in 77.5% of patients versus 47.5% by gonioscopy. The extent of angle seen was similar by both methods. Agreement between RetCam and gonioscopy images regarding details of angle structures was 72.50% by observer 1 and 65.00% by observer 2. Conclusions: There was good agreement between RetCam and indirect gonioscopy images in detecting angle structures of congenital glaucoma patients. However, RetCam provided greater clarity, with better quality, and higher magnification images. RetCam can be a useful alternative to gonioscopy in infants and small children without the need for general anesthesia.

Subaru Weak-lensing Survey of Dark Matter Subhalos in the Coma Cluster: Subhalo Mass Function and Statistical Properties

Science.gov (United States)

Okabe, Nobuhiro; Futamase, Toshifumi; Kajisawa, Masaru; Kuroshima, Risa

2014-04-01

We present a 4 deg2 weak gravitational lensing survey of subhalos in the very nearby Coma cluster using the Subaru/Suprime-Cam. The large apparent size of cluster subhalos allows us to measure the mass of 32 subhalos detected in a model-independent manner, down to the order of 10-3 of the virial mass of the cluster. Weak-lensing mass measurements of these shear-selected subhalos enable us to investigate subhalo properties and the correlation between subhalo masses and galaxy luminosities for the first time. The mean distortion profiles stacked over subhalos show a sharply truncated feature which is well-fitted by a Navarro-Frenk-White (NFW) mass model with the truncation radius, as expected due to tidal destruction by the main cluster. We also found that subhalo masses, truncation radii, and mass-to-light ratios decrease toward the cluster center. The subhalo mass function, dn/dln M sub, in the range of 2 orders of magnitude in mass, is well described by a single power law or a Schechter function. Best-fit power indices of 1.09^{+0.42}_{-0.32} for the former model and 0.99_{-0.23}^{+0.34} for the latter, are in remarkable agreement with slopes of ~0.9-1.0 predicted by the cold dark matter paradigm. The tangential distortion signals in the radial range of 0.02-2 h -1 Mpc from the cluster center show a complex structure which is well described by a composition of three mass components of subhalos, the NFW mass distribution as a smooth component of the main cluster, and a lensing model from a large scale structure behind the cluster. Although the lensing signals are 1 order of magnitude lower than those for clusters at z ~ 0.2, the total signal-to-noise ratio, S/N = 13.3, is comparable, or higher, because the enormous number of background source galaxies compensates for the low lensing efficiency of the nearby cluster. Based on data collected from the Subaru Telescope and obtained from SMOKA, operated by the Astronomy Data Center, National Astronomical Observatory of

SILVERRUSH. V. Census of Lyα, [O III] λ5007, Hα, and [C II] 158 μm Line Emission with ∼1000 LAEs at z = 4.9–7.0 Revealed with Subaru/HSC

Science.gov (United States)

Harikane, Yuichi; Ouchi, Masami; Shibuya, Takatoshi; Kojima, Takashi; Zhang, Haibin; Itoh, Ryohei; Ono, Yoshiaki; Higuchi, Ryo; Inoue, Akio K.; Chevallard, Jacopo; Capak, Peter L.; Nagao, Tohru; Onodera, Masato; Faisst, Andreas L.; Martin, Crystal L.; Rauch, Michael; Bruzual, Gustavo A.; Charlot, Stephane; Davidzon, Iary; Fujimoto, Seiji; Hilmi, Miftahul; Ilbert, Olivier; Lee, Chien-Hsiu; Matsuoka, Yoshiki; Silverman, John D.; Toft, Sune

2018-06-01

We investigate Lyα, [O III] λ5007, Hα, and [C II] 158 μm emission from 1124 galaxies at z = 4.9–7.0. Our sample is composed of 1092 Lyα emitters (LAEs) at z = 4.9, 5.7, 6.6, and 7.0 identified by Subaru/Hyper-Suprime-Cam (HSC) narrowband surveys covered by Spitzer Large Area Survey with Hyper-Suprime-Cam (SPLASH) and 34 galaxies at z = 5.148–7.508 with deep ALMA [C II] 158 μm data in the literature. Fluxes of strong rest-frame optical lines of [O III] and Hα (Hβ) are constrained by significant excesses found in the SPLASH 3.6 and 4.5 μm photometry. At z = 4.9, we find that the rest-frame Hα equivalent width and the Lyα escape fraction f Lyα positively correlate with the rest-frame Lyα equivalent width {EW}}Lyα }0. The {f}Lyα }{--}{EW}}Lyα }0 correlation is similarly found at z ∼ 0–2, suggesting no evolution of the correlation over z ≃ 0–5. The typical ionizing photon production efficiency of LAEs is log(ξ ion/[Hz erg‑1]) ≃ 25.5, significantly (60%–100%) higher than those of LBGs at a given UV magnitude. At z = 5.7–7.0, there exists an interesting turnover trend that the [O III]/Hα flux ratio increases in {EW}}Lyα }0≃ 0{--}30 \\mathringA and then decreases out to {EW}}Lyα }0≃ 130 \\mathringA . We also identify an anticorrelation between a ratio of [C II] luminosity to star formation rate (L [C II]/SFR) and {EW}}Lyα }0 at the >99% confidence level.. We carefully investigate physical origins of the correlations with stellar-synthesis and photoionization models and find that a simple anticorrelation between {EW}}Lyα }0 and metallicity explains self-consistently all of the correlations of Lyα, Hα, [O III]/Hα, and [C II] identified in our study, indicating detections of metal-poor (∼0.03 Z ⊙) galaxies with {EW}}Lyα }0≃ 200 \\mathringA .

Use of EyeCam for imaging the anterior chamber angle.

Science.gov (United States)

Perera, Shamira A; Baskaran, Mani; Friedman, David S; Tun, Tin A; Htoon, Hla M; Kumar, Rajesh S; Aung, Tin

2010-06-01

To compare EyeCam (Clarity Medical Systems, Pleasanton, CA) imaging with gonioscopy for detecting angle closure. In this prospective, hospital-based study, subjects underwent gonioscopy by a single observer and EyeCam imaging by a different operator. EyeCam images were graded by two masked observers. The anterior chamber angle in a quadrant was classified as closed if the trabecular meshwork could not be seen. The eye was classified as having angle closure if two or more quadrants were closed. One hundred fifty-two subjects were studied. The mean age was 57.4 years (SD 12.9) and there were 82 (54%) men. Of the 152 eyes, 21 (13.8%) had angle closure. The EyeCam provided clear images of the angles in 98.8% of subjects. The agreement between the EyeCam and gonioscopy for detecting angle closure in the superior, inferior, nasal, and temporal quadrants based on agreement coefficient (AC1) statistics was 0.73, 0.75, 0.76, and 0.72, respectively. EyeCam detected more closed angles than did gonioscopy in all quadrants (P gonioscopy, 21/152 (13.8%) eyes were diagnosed as angle closure compared to 41 (27.0%) of 152 with EyeCam (P gonioscopy for detecting angle closure. However, it detected more closed angles than did gonioscopy in all quadrants.

The mechanical design of CHARIS: an exoplanet IFS for the Subaru Telescope

Science.gov (United States)

Galvin, Michael B.; Carr, Michael A.; Groff, Tyler D.; Kasdin, N. Jeremy; Fagan, Radford; Hayashi, Masahiko; Takato, Naruhisa

2014-07-01

Princeton University is designing and building an integral field spectrograph (IFS), the Coronagraphic High Angular Resolution Imaging Spectrograph (CHARIS), for integration with the Subaru Corona Extreme Adaptive Optics (SCExAO) system and the AO188 adaptive optics system on the Subaru Telescope. CHARIS and SCExAO will measure spectra of hot, young Jovian planets in a coronagraphic image across J, H, and K bands down to an 80 milliarcsecond inner working angle. Here we present the current status of the mechanical design of the CHARIS instrument.

A Keck/DEIMOS spectroscopic survey of the faint M31 satellites AndIX, AndXI, AndXII and AndXIII†

Science.gov (United States)

Collins, M. L. M.; Chapman, S. C.; Irwin, M. J.; Martin, N. F.; Ibata, R. A.; Zucker, D. B.; Blain, A.; Ferguson, A. M. N.; Lewis, G. F.; McConnachie, A. W.; Peñarrubia, J.

2010-10-01

We present the first spectroscopic analysis of the faint M31 satellite galaxies, AndXI and AndXIII, as well as a re-analysis of existing spectroscopic data for two further faint companions, AndIX (correcting for an error in earlier geometric modelling that caused a misclassification of member stars in previous work) and AndXII. By combining data obtained using the Deep Imaging Multi-Object Spectrograph (DEIMOS) mounted on the Keck II telescope with deep photometry from the Suprime-Cam instrument on Subaru, we have identified the most probable members for each of the satellites based on their radial velocities (precise to several down to i ~ 22), distance from the centre of the dwarf spheroidal galaxies (dSphs) and their photometric [Fe/H]. Using both the photometric and spectroscopic data, we have also calculated global properties for the dwarfs, such as systemic velocities, metallicities and half-light radii. We find each dwarf to be very metal poor ([Fe/H] ~ -2 both photometrically and spectroscopically, from their stacked spectrum), and as such, they continue to follow the luminosity-metallicity relationship established with brighter dwarfs. We are unable to resolve dispersion for AndXI due to small sample size and low signal-to-noise ratio, but we set a 1σ upper limit of σv financial support of the W.M. Keck Foundation. Based in part on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan. ‡ E-mail: mlmc2@ast.cam.ac.uk

JunoCam Images of Jupiter: Science from an Outreach Experiment

Science.gov (United States)

Hansen, C. J.; Orton, G. S.; Caplinger, M. A.; Ravine, M. A.; Rogers, J.; Eichstädt, G.; Jensen, E.; Bolton, S. J.; Momary, T.; Ingersoll, A. P.

2017-12-01

The Juno mission to Jupiter carries a visible imager on its payload primarily for outreach, and also very useful for jovian atmospheric science. Lacking a formal imaging science team, members of the public have volunteered to process JunoCam images. Lightly processed and raw JunoCam data are posted on the JunoCam webpage at https://missionjuno.swri.edu/junocam/processing. Citizen scientists download these images and upload their processed contributions. JunoCam images through broadband red, green and blue filters and a narrowband methane filter centered at 889 nm mounted directly on the detector. JunoCam is a push-frame imager with a 58 deg wide field of view covering a 1600 pixel width, and builds the second dimension of the image as the spacecraft rotates. This design enables capture of the entire pole of Jupiter in a single image at low emission angle when Juno is 1 hour from perijove (closest approach). At perijove the wide field of view images are high-resolution while still capturing entire storms, e.g. the Great Red Spot. Juno's unique polar orbit yields polar perspectives unavailable to earth-based observers or most previous spacecraft. The first discovery was that the familiar belt-zone structure gives way to more chaotic storms, with cyclones grouped around both the north and south poles [1, 2]. Recent time-lapse sequences have enabled measurement of the rotation rates and wind speeds of these circumpolar cyclones [3]. Other topics are being investigated with substantial, in many cases essential, contributions from citizen scientists. These include correlating the high resolution JunoCam images to storms and disruptions of the belts and zones tracked throughout the historical record. A phase function for Jupiter is being developed empirically to allow image brightness to be flattened from the subsolar point to the terminator. We are studying high hazes and the stratigraphy of the upper atmosphere, utilizing the methane filter, structures illuminated

A redshift determination of the host galaxy

Energy Technology Data Exchange (ETDEWEB)

Urata, Y. [RIKEN, Saitama (Japan); Tokyo Institute of Technology, Tokyo (Japan). Department of Physics; Yoshida, A. [Aoyama Garkuin Univ., Kanagawa (Japan). Department of Physics; Yamada, T. [National Astronomical Observatory, Tokyo (Japan)] (and others)

2005-07-15

Using the Suprime-Cam on the Subaru telescope, we carried out deep multi band (V, R, I, z') imaging for the host galaxy of GRB980329, which is one of well studied optically dark gamma- ray bursts. The host galaxy was detected clearly in all bands. Combining these measurements with published near-infrared data, we determined the photometric redshift of the galaxy as z = 3.56 (3.21-3.79 at 90 range). The implied V-band extinction is rather low, typically {approx} 1 mag. At z = 3.56, the isotropic 40-700 keV total energy of GRB980329 is calculated as (2.1 {+-} 0.4) x 10{sup 54} erg. Assuming that this GRB was emitted by a pair of jets with a total energy of 10{sup 51} ergs, their opening angle is calculated as {theta}{sub j} = 2.1. The present results disfavor the high-redshift hypothesis and the high extinction scenario of optically dark bursts.0.

A redshift determination of the host galaxy

International Nuclear Information System (INIS)

Urata, Y.

2005-01-01

Using the Suprime-Cam on the Subaru telescope, we carried out deep multi band (V, R, I, z') imaging for the host galaxy of GRB980329, which is one of well studied optically dark gamma- ray bursts. The host galaxy was detected clearly in all bands. Combining these measurements with published near-infrared data, we determined the photometric redshift of the galaxy as z = 3.56 (3.21-3.79 at 90 range). The implied V-band extinction is rather low, typically ∼ 1 mag. At z = 3.56, the isotropic 40-700 keV total energy of GRB980329 is calculated as (2.1 ± 0.4) x 10 54 erg. Assuming that this GRB was emitted by a pair of jets with a total energy of 10 51 ergs, their opening angle is calculated as θ j = 2.1. The present results disfavor the high-redshift hypothesis and the high extinction scenario of optically dark bursts

H0LiCOW VIII. A weak lensing measurement of the external convergence in the field of the lensed quasar HE 0435-1223

Science.gov (United States)

Tihhonova, O.; Courbin, F.; Harvey, D.; Hilbert, S.; Rusu, C. E.; Fassnacht, C. D.; Bonvin, V.; Marshall, P. J.; Meylan, G.; Sluse, D.; Suyu, S. H.; Treu, T.; Wong, K. C.

2018-04-01

We present a weak gravitational lensing measurement of the external convergence along the line of sight to the quadruply lensed quasar HE 0435-1223. Using deep r-band images from Subaru-Suprime-Cam we observe galaxies down to a 3σ limiting magnitude of ˜26 mags resulting in a source galaxy density of 14 galaxies / arcmin2 after redshift-based cuts. Using an inpainting technique and Multi-Scale Entropy filtering algorithm, we find that the region in close proximity to the lens has an estimated external convergence of κ =-0.012^{+0.020}_{-0.013} and is hence marginally under-dense. We also rule out the presence of any halo with a mass greater than Mvir = 1.6 × 1014h-1M⊙ (68% confidence limit). Our results, consistent with previous studies of this lens, confirm that the intervening mass along the line of sight to HE 0435-1223 does not affect significantly the cosmological results inferred from the time delay measurements of that specific object.

Clustering of quasars in a wide luminosity range at redshift 4 with Subaru Hyper Suprime-Cam Wide-field imaging

Science.gov (United States)

He, Wanqiu; Akiyama, Masayuki; Bosch, James; Enoki, Motohiro; Harikane, Yuichi; Ikeda, Hiroyuki; Kashikawa, Nobunari; Kawaguchi, Toshihiro; Komiyama, Yutaka; Lee, Chien-Hsiu; Matsuoka, Yoshiki; Miyazaki, Satoshi; Nagao, Tohru; Nagashima, Masahiro; Niida, Mana; Nishizawa, Atsushi J.; Oguri, Masamune; Onoue, Masafusa; Oogi, Taira; Ouchi, Masami; Schulze, Andreas; Shirasaki, Yuji; Silverman, John D.; Tanaka, Manobu M.; Tanaka, Masayuki; Toba, Yoshiki; Uchiyama, Hisakazu; Yamashita, Takuji

2018-01-01

We examine the clustering of quasars over a wide luminosity range, by utilizing 901 quasars at \\overline{z}_phot˜ 3.8 with -24.73 Strategic Program (HSC-SSP) S16A Wide2 date release and 342 more luminous quasars at 3.4 Digital Sky Survey that fall in the HSC survey fields. We measure the bias factors of two quasar samples by evaluating the cross-correlation functions (CCFs) between the quasar samples and 25790 bright z ˜ 4 Lyman break galaxies in M1450 < -21.25 photometrically selected from the HSC dataset. Over an angular scale of 10.0" to 1000.0", the bias factors are 5.93+1.34-1.43 and 2.73+2.44-2.55 for the low- and high-luminosity quasars, respectively, indicating no significant luminosity dependence of quasar clustering at z ˜ 4. It is noted that the bias factor of the luminous quasars estimated by the CCF is smaller than that estimated by the auto-correlation function over a similar redshift range, especially on scales below 40.0". Moreover, the bias factor of the less-luminous quasars implies the minimal mass of their host dark matter halos is 0.3-2 × 1012 h-1 M⊙, corresponding to a quasar duty cycle of 0.001-0.06.

GammaCam trademark radiation imaging system

International Nuclear Information System (INIS)

1998-02-01

GammaCam trademark, a gamma-ray imaging system manufactured by AIL System, Inc., would benefit a site that needs to locate radiation sources. It is capable of producing a two-dimensional image of a radiation field superimposed on a black and white visual image. Because the system can be positioned outside the radiologically controlled area, the radiation exposure to personnel is significantly reduced and extensive shielding is not required. This report covers the following topics: technology description; performance; technology applicability and alternatives; cost; regulatory and policy issues; and lessons learned. The demonstration of GammaCam trademark in December 1996 was part of the Large-Scale Demonstration Project (LSDP) whose objective is to select and demonstrate potentially beneficial technologies at the Argonne National Laboratory-East (ANL) Chicago Pile-5 Research Reactor (CP-5). The purpose of the LSDP is to demonstrate that by using innovative and improved decontamination and decommissioning (D and D) technologies from various sources, significant benefits can be achieved when compared to baseline D and D technologies

Discovery of nine extended ionized gas clouds in a z = 0.4 cluster

Energy Technology Data Exchange (ETDEWEB)

Yagi, Masafumi; Koyama, Yusei; Kodama, Tadayuki [Optical and Infrared Astronomy Division, National Astronomical Observatory of Japan, 2-21-1, Osawa, Mitaka, Tokyo, 181-8588 (Japan); Gu, Liyi [Research Center for the Early Universe, School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0011 (Japan); Nakata, Fumiaki; Hattori, Takashi [Subaru Telescope, 650 North A' ohoku Place, Hilo, HI 96720 (United States); Yoshida, Michitoshi, E-mail: YAGI.Masafumi@nao.ac.jp [Hiroshima Astrophysical Science Center, Hiroshima University, 1-3-1, Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8526 (Japan)

2015-02-01

From deep Hα imaging data of Suprime-Cam/Subaru, we discovered nine extended ionized gas clouds (EIG) around galaxies in the Abell 851 cluster (A851) at z = 0.4. We surveyed a 30 × 25 arcmin region, and the EIGs were found only near the cluster center (<2.3 arcmin ∼ 750 kpc). The parent galaxies of the EIGs are star-forming or post-starburst galaxies, all of which are spectroscopically confirmed members of the cluster. Four out of the nine parent galaxies show distortion of stellar distribution in the disk, which can be a sign of recent interaction, and the interaction may have made the EIGs. On the other hand, six parent galaxies (one overlaps those exhibiting distortion) show Hα emission without stars, which implies ram pressure stripping. The spectrum of the brightest parent galaxy shows a post-starburst signature and resembles the Hα stripped galaxies found in the Coma cluster. Meanwhile, two brightest parent galaxies in A851 are more massive than the EIG parent galaxies in the Coma cluster. This is consistent with a “downsizing” of star-forming galaxies, though it is still within the statistical variance. We also analyzed Suprime-Cam data of another z=0.39 cluster, CL0024+17, but found no EIGs. The key difference between A851 and CL0024+17 would be the existence of a subcluster colliding with the main body of A851, in which six or seven out of the nine parent galaxies in A851 exist, and the fraction of EIGs in the subcluster is significantly higher than the main subcluster of A851 and CL0024+17.

Discovery of nine extended ionized gas clouds in a z = 0.4 cluster

International Nuclear Information System (INIS)

Yagi, Masafumi; Koyama, Yusei; Kodama, Tadayuki; Gu, Liyi; Nakata, Fumiaki; Hattori, Takashi; Yoshida, Michitoshi

2015-01-01

From deep Hα imaging data of Suprime-Cam/Subaru, we discovered nine extended ionized gas clouds (EIG) around galaxies in the Abell 851 cluster (A851) at z = 0.4. We surveyed a 30 × 25 arcmin region, and the EIGs were found only near the cluster center (<2.3 arcmin ∼ 750 kpc). The parent galaxies of the EIGs are star-forming or post-starburst galaxies, all of which are spectroscopically confirmed members of the cluster. Four out of the nine parent galaxies show distortion of stellar distribution in the disk, which can be a sign of recent interaction, and the interaction may have made the EIGs. On the other hand, six parent galaxies (one overlaps those exhibiting distortion) show Hα emission without stars, which implies ram pressure stripping. The spectrum of the brightest parent galaxy shows a post-starburst signature and resembles the Hα stripped galaxies found in the Coma cluster. Meanwhile, two brightest parent galaxies in A851 are more massive than the EIG parent galaxies in the Coma cluster. This is consistent with a “downsizing” of star-forming galaxies, though it is still within the statistical variance. We also analyzed Suprime-Cam data of another z=0.39 cluster, CL0024+17, but found no EIGs. The key difference between A851 and CL0024+17 would be the existence of a subcluster colliding with the main body of A851, in which six or seven out of the nine parent galaxies in A851 exist, and the fraction of EIGs in the subcluster is significantly higher than the main subcluster of A851 and CL0024+17.

Comparative evaluation of RetCam vs. gonioscopy images in congenital glaucoma

OpenAIRE

Azad, Raj V; Chandra, Parijat; Chandra, Anuradha; Gupta, Aparna; Gupta, Viney; Sihota, Ramanjit

2014-01-01

Purpose: To compare clarity, exposure and quality of anterior chamber angle visualization in congenital glaucoma patients, using RetCam and indirect gonioscopy images. Design: Cross-sectional study Participants. Congenital glaucoma patients over age of 5 years. Materials and Methods: A prospective consecutive pilot study was done in congenital glaucoma patients who were older than 5 years. Methods used are indirect gonioscopy and RetCam imaging. Clarity of the image, extent of angle visible a...

LARGE AREA SURVEY FOR z = 7 GALAXIES IN SDF AND GOODS-N: IMPLICATIONS FOR GALAXY FORMATION AND COSMIC REIONIZATION

International Nuclear Information System (INIS)

Ouchi, Masami; Mobasher, Bahram; Shimasaku, Kazuhiro; Ono, Yoshiaki; Nakajima, Kimihiko; Okamura, Sadanori; Ferguson, Henry C.; Fall, S. Michael; Kashikawa, Nobunari; Morokuma, Tomoki; Dickinson, Mark; Giavalisco, Mauro; Ohta, Kouji

2009-01-01

We present results of our large area survey for z'-band dropout galaxies at z = 7 in a 1568 arcmin 2 sky area covering the SDF and GOODS-N fields. Combining our ultra-deep Subaru/Suprime-Cam z'- and y-band (λ eff = 1 μm) images with legacy data of Subaru and Hubble Space Telescope, we have identified 22 bright z-dropout galaxies down to y = 26, one of which has a spectroscopic redshift of z = 6.96 determined from Lyα emission. The z = 7 luminosity function yields the best-fit Schechter parameters of φ* = 0.69 +2.62 -0.55 x 10 -3 Mpc -3 , M* UV = -20.10 ± 0.76 mag, and α = -1.72 ± 0.65, and indicates a decrease from z = 6 at a >95% confidence level. This decrease is beyond the cosmic variance in our two fields, which is estimated to be a factor of ∼ 0.2), a lower metallicity, and/or a flatter initial mass function. Our SDF z-dropout galaxies appear to form 60 Mpc long filamentary structures, and the z = 6.96 galaxy with Lyα emission is located at the center of an overdense region consisting of four UV bright dropout candidates, which might suggest an existence of a well-developed ionized bubble at z = 7.

METALLICITY AND AGE OF THE STELLAR STREAM AROUND THE DISK GALAXY NGC 5907

Energy Technology Data Exchange (ETDEWEB)

Laine, Seppo; Grillmair, Carl J.; Capak, Peter [Spitzer Science Center-Caltech, MS 314-6, Pasadena, CA 91125 (United States); Arendt, Richard G. [CRESST/UMBC/NASA GSFC, Code 665, Greenbelt, MD 20771 (United States); Romanowsky, Aaron J. [Department of Physics and Astronomy, San José State University, One Washington Square, San Jose, CA 95192 (United States); Martínez-Delgado, David [Astronomisches Rechen-Institut, Zentrum für Astronomie der Universität Heidelberg, Mönchhofstr. 12-14, D-69120 Heidelberg (Germany); Ashby, Matthew L. N. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Davies, James E. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Majewski, Stephen R. [Department of Astronomy, University of Virginia, P.O. Box 400325, Charlottesville, VA 22904-4325 (United States); Brodie, Jean P.; Arnold, Jacob A. [University of California Observatories and Department of Astronomy and Astrophysics, University of California, 1156 High Street, Santa Cruz, CA 95064 (United States); GaBany, R. Jay, E-mail: seppo@ipac.caltech.edu [Black Bird Observatory, 5660 Brionne Drive, San Jose, CA 95118 (United States)

2016-09-01

Stellar streams have become central to studies of the interaction histories of nearby galaxies. To characterize the most prominent parts of the stellar stream around the well-known nearby ( d  = 17 Mpc) edge-on disk galaxy NGC 5907, we have obtained and analyzed new, deep gri Subaru/Suprime-Cam and 3.6 μ m Spitzer /Infrared Array Camera observations. Combining the near-infrared 3.6 μ m data with visible-light images allows us to use a long wavelength baseline to estimate the metallicity and age of the stellar population along an ∼60 kpc long segment of the stream. We have fitted the stellar spectral energy distribution with a single-burst stellar population synthesis model and we use it to distinguish between the proposed satellite accretion and minor/major merger formation models of the stellar stream around this galaxy. We conclude that a massive minor merger (stellar mass ratio of at least 1:8) can best account for the metallicity of −0.3 inferred along the brightest parts of the stream.

The UV Survey Mission Concept, CETUS

Science.gov (United States)

Heap, Sara; and the CETUS Team

2018-01-01

In March 2017, NASA selected CETUS for study of a Probe-class mission concept. W. Danchi is the CETUS PI, and S. Heap is the Science PI. CETUS is primarily a UV survey telescope to complement survey telescopes of the 2020’s including E-ROSITA, Subaru Hyper Suprime Cam and Prime-Focus Spectrograph, WFIRST, and the Square Kilometer Array. CETUS comprises a 1.5-m wide-field telescope and three science instruments: a wide-field (1045” on a side) far-UV and near-UV camera; a similarly wide-field near-UV multi-object spectrograph utilizing a next-generation micro-shutter array; and a single-object spectrograph with options of spectral region (far-UV or near-UV) and spectral resolving power (2,000 or 40,000). The survey instruments will operate simultaneously thereby producing wide-field images in the near-UV and far-UV and a spectrogram containing near-UV spectra of up to 100 sources free of spectral overlap and astronomical background. ln concert with other survey telescopes, CETUS will focus on understanding galaxy evolution at cosmic noon (z~1-2).

Subaru weak-lensing survey of dark matter subhalos in the Coma cluster: Subhalo mass function and statistical properties

International Nuclear Information System (INIS)

Okabe, Nobuhiro; Futamase, Toshifumi; Kuroshima, Risa; Kajisawa, Masaru

2014-01-01

We present a 4 deg 2 weak gravitational lensing survey of subhalos in the very nearby Coma cluster using the Subaru/Suprime-Cam. The large apparent size of cluster subhalos allows us to measure the mass of 32 subhalos detected in a model-independent manner, down to the order of 10 –3 of the virial mass of the cluster. Weak-lensing mass measurements of these shear-selected subhalos enable us to investigate subhalo properties and the correlation between subhalo masses and galaxy luminosities for the first time. The mean distortion profiles stacked over subhalos show a sharply truncated feature which is well-fitted by a Navarro-Frenk-White (NFW) mass model with the truncation radius, as expected due to tidal destruction by the main cluster. We also found that subhalo masses, truncation radii, and mass-to-light ratios decrease toward the cluster center. The subhalo mass function, dn/dln M sub , in the range of 2 orders of magnitude in mass, is well described by a single power law or a Schechter function. Best-fit power indices of 1.09 −0.32 +0.42 for the former model and 0.99 −0.23 +0.34 for the latter, are in remarkable agreement with slopes of ∼0.9-1.0 predicted by the cold dark matter paradigm. The tangential distortion signals in the radial range of 0.02-2 h –1 Mpc from the cluster center show a complex structure which is well described by a composition of three mass components of subhalos, the NFW mass distribution as a smooth component of the main cluster, and a lensing model from a large scale structure behind the cluster. Although the lensing signals are 1 order of magnitude lower than those for clusters at z ∼ 0.2, the total signal-to-noise ratio, S/N = 13.3, is comparable, or higher, because the enormous number of background source galaxies compensates for the low lensing efficiency of the nearby cluster.

A Comparison of Galaxy Bulge+Disk Decomposition Between Pan-STARRS and SDSS

Science.gov (United States)

Lokken, Martine Elena; McPartland, Conor; Sanders, David B.

2018-01-01

Measurements of the size and shape of bulges in galaxies provide key constraints for models of galaxy evolution. A comprehensive catalog of bulge measurements for Sloan Digital Sky Survey (SDSS) DR7 galaxies is currently available to the public. However, the Pan-STARRS1 (PS1) 3π survey now covers the same region with ~1-2 mag deeper photometry, a ~10-30% smaller PSF, and additional coverage in y-band. To test how much improvement in galaxy parameter measurements (e.g. bulge + disk) can be achieved using the new PS1 data, we make use of ultra-deep imaging data from the Hyper Suprime-Cam (HSC) Subaru Strategic Program (SSP). We fit bulge+disk models to images of 372 bright (mi SSP images shows a tighter correlation between PS1 and SSP measurements for both bulge and disk parameters. Bulge parameters, such as bulge-to-total fraction and bulge radius, show the strongest improvement. However, measurements of all parameters degrade for galaxies with total r-band magnitude below the SDSS spectroscopic limit, mr = 17.7. We plan to use the PS1 3π survey data to produce an updated catalog of bulge+disk decomposition measurements for the entire SDSS DR7 spectroscopic galaxy sample.

The sluggs survey: HST/ACS mosaic imaging of the NGC 3115 globular cluster system

Energy Technology Data Exchange (ETDEWEB)

Jennings, Zachary G.; Romanowsky, Aaron J.; Brodie, Jean P.; Arnold, Jacob A. [University of California Observatories, Santa Cruz, CA 95064 (United States); Strader, Jay [Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan, MI 48824 (United States); Lin, Dacheng; Irwin, Jimmy A.; Wong, Ka-Wah [Department of Physics and Astronomy, University of Alabama, Box 870324, Tuscaloosa, AL 35487 (United States); Sivakoff, Gregory R., E-mail: zgjennin@ucsc.edu [Department of Physics, University of Alberta, Edmonton, Alberta T6G 2E1 (Canada)

2014-08-01

We present Hubble Space Telescope/Advanced Camera for Surveys (HST/ACS) g and z photometry and half-light radii R {sub h} measurements of 360 globular cluster (GC) candidates around the nearby S0 galaxy NGC 3115. We also include Subaru/Suprime-Cam g, r, and i photometry of 421 additional candidates. The well-established color bimodality of the GC system is obvious in the HST/ACS photometry. We find evidence for a 'blue tilt' in the blue GC subpopulation, wherein the GCs in the blue subpopulation get redder as luminosity increases, indicative of a mass-metallicity relationship. We find a color gradient in both the red and blue subpopulations, with each group of clusters becoming bluer at larger distances from NGC 3115. The gradient is of similar strength in both subpopulations, but is monotonic and more significant for the blue clusters. On average, the blue clusters have ∼10% larger R {sub h} than the red clusters. This average difference is less than is typically observed for early-type galaxies but does match that measured in the literature for the Sombrero Galaxy (M104), suggesting that morphology and inclination may affect the measured size difference between the red and blue clusters. However, the scatter on the R {sub h} measurements is large. We also identify 31 clusters more extended than typical GCs, which we term ultra-compact dwarf (UCD) candidates. Many of these objects are actually considerably fainter than typical UCDs. While it is likely that a significant number will be background contaminants, six of these UCD candidates are spectroscopically confirmed as NGC 3115 members. To explore the prevalence of low-mass X-ray binaries in the GC system, we match our ACS and Suprime-Cam detections to corresponding Chandra X-ray sources. We identify 45 X-ray-GC matches: 16 among the blue subpopulation and 29 among the red subpopulation. These X-ray/GC coincidence fractions are larger than is typical for most GC systems, probably due to the increased

Volume phase holographic gratings for the Subaru Prime Focus Spectrograph: performance measurements of the prototype grating set

Science.gov (United States)

Barkhouser, Robert H.; Arns, James; Gunn, James E.

2014-08-01

The Prime Focus Spectrograph (PFS) is a major instrument under development for the 8.2 m Subaru telescope on Mauna Kea. Four identical, fixed spectrograph modules are located in a room above one Nasmyth focus. A 55 m fiber optic cable feeds light into the spectrographs from a robotic fiber positioner mounted at the telescope prime focus, behind the wide field corrector developed for Hyper Suprime-Cam. The positioner contains 2400 fibers and covers a 1.3 degree hexagonal field of view. Each spectrograph module will be capable of simultaneously acquiring 600 spectra. The spectrograph optical design consists of a Schmidt collimator, two dichroic beamsplitters to separate the light into three channels, and for each channel a volume phase holographic (VPH) grating and a dual- corrector, modified Schmidt reimaging camera. This design provides a 275 mm collimated beam diameter, wide simultaneous wavelength coverage from 380 nm to 1.26 µm, and good imaging performance at the fast f/1.1 focal ratio required from the cameras to avoid oversampling the fibers. The three channels are designated as the blue, red, and near-infrared (NIR), and cover the bandpasses 380-650 nm (blue), 630-970 nm (red), and 0.94-1.26 µm (NIR). A mosaic of two Hamamatsu 2k×4k, 15 µm pixel CCDs records the spectra in the blue and red channels, while the NIR channel employs a 4k×4k, substrate-removed HAWAII-4RG array from Teledyne, with 15 µm pixels and a 1.7 µm wavelength cutoff. VPH gratings have become the dispersing element of choice for moderate-resolution astronomical spectro- graphs due their potential for very high diffraction efficiency, low scattered light, and the more compact instru- ment designs offered by transmissive dispersers. High quality VPH gratings are now routinely being produced in the sizes required for instruments on large telescopes. These factors made VPH gratings an obvious choice for PFS. In order to reduce risk to the project, as well as fully exploit the performance

HectoMAPping the Universe. Karl Schwarzschild Award Lecture 2014

Science.gov (United States)

Geller, Margaret J.; Hwang, Ho Seong

2015-06-01

During the last three decades progress in mapping the Universe from an age of 400 000 years to the present has been stunning. Instrument/telescope combinations have naturally determined the sampling of various redshift ranges. Here we outline the impact of the Hectospec on the MMT on exploration of the Universe in the redshift range 0.2 ⪉ z ⪉ 0.8. We focus on dense redshift surveys, SHELS and HectoMAP. SHELS is a complete magnitude limited survey covering 8 square degrees. The HectoMAP survey combines a red-selected dense redshift survey and a weak lensing map covering 50 square degrees. Combining the dense redshift survey with a Subaru HyperSuprimeCam (HSC) weak lensing map will provide a powerful probe of the way galaxies trace the distribution of dark matter on a wide range of physical scales.

A 16 deg2 survey of emission-line galaxies at z SSP Public Data Release 1

Science.gov (United States)

Hayashi, Masao; Tanaka, Masayuki; Shimakawa, Rhythm; Furusawa, Hisanori; Momose, Rieko; Koyama, Yusei; Silverman, John D.; Kodama, Tadayuki; Komiyama, Yutaka; Leauthaud, Alexie; Lin, Yen-Ting; Miyazaki, Satoshi; Nagao, Tohru; Nishizawa, Atsushi J.; Ouchi, Masami; Shibuya, Takatoshi; Tadaki, Ken-ichi; Yabe, Kiyoto

2018-01-01

We present initial results from the Subaru Strategic Program (SSP) with Hyper Suprime-Cam (HSC) on a comprehensive survey of emission-line galaxies at z SSP fields suggests that a survey volume of >5 × 105 Mpc3 is essential to overcome cosmic variance. Since the current data have not reached the full depth expected for the HSC-SSP, the color cut in i - NB816 or z - NB921 induces a bias towards star-forming galaxies with large equivalent widths, primarily seen in the stellar mass functions for the H α emitters at z ≈ 0.25-0.40. Even so, the emission-line galaxies clearly cover a wide range of luminosity, stellar mass, and environment, thus demonstrating the usefulness of the narrowband data from the HSC-SSP for investigating star-forming galaxies at z < 1.5.

LoCuSS: THE MASS DENSITY PROFILE OF MASSIVE GALAXY CLUSTERS AT z = 0.2 {sup ,}

Energy Technology Data Exchange (ETDEWEB)

Okabe, Nobuhiro; Umetsu, Keiichi [Academia Sinica Institute of Astronomy and Astrophysics (ASIAA), P. O. Box 23-141, Taipei 10617, Taiwan (China); Smith, Graham P. [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom); Takada, Masahiro [Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), University of Tokyo, Chiba 277-8582 (Japan); Futamase, Toshifumi, E-mail: okabe@asiaa.sinica.edu.tw, E-mail: gps@star.sr.bham.ac.uk [Astronomical Institute, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578 (Japan)

2013-06-01

We present a stacked weak-lensing analysis of an approximately mass-selected sample of 50 galaxy clusters at 0.15 < z < 0.3, based on observations with Suprime-Cam on the Subaru Telescope. We develop a new method for selecting lensed background galaxies from which we estimate that our sample of red background galaxies suffers just 1% contamination. We detect the stacked tangential shear signal from the full sample of 50 clusters, based on this red sample of background galaxies, at a total signal-to-noise ratio of 32.7. The Navarro-Frenk-White model is an excellent fit to the data, yielding sub-10% statistical precision on mass and concentration: M{sub vir}=7.19{sup +0.53}{sub -0.50} Multiplication-Sign 10{sup 14} h{sup -1} M{sub sun}, c{sub vir}=5.41{sup +0.49}{sub -0.45} (c{sub 200}=4.22{sup +0.40}{sub -0.36}). Tests of a range of possible systematic errors, including shear calibration and stacking-related issues, indicate that they are subdominant to the statistical errors. The concentration parameter obtained from stacking our approximately mass-selected cluster sample is broadly in line with theoretical predictions. Moreover, the uncertainty on our measurement is comparable with the differences between the different predictions in the literature. Overall, our results highlight the potential for stacked weak-lensing methods to probe the mean mass density profile of cluster-scale dark matter halos with upcoming surveys, including Hyper-Suprime-Cam, Dark Energy Survey, and KIDS.

THE FOSSIL RECORD OF TWO-PHASE GALAXY ASSEMBLY: KINEMATICS AND METALLICITIES IN THE NEAREST S0 GALAXY

International Nuclear Information System (INIS)

Arnold, Jacob A.; Romanowsky, Aaron J.; Brodie, Jean P.; Chomiuk, Laura; Strader, Jay; Spitler, Lee R.; Forbes, Duncan A.; Benson, Andrew J.

2011-01-01

We present a global analysis of kinematics and metallicity in the nearest S0 galaxy, NGC 3115, along with implications for its assembly history. The data include high-quality wide-field imaging from Suprime-Cam on the Subaru telescope, and multi-slit spectra of the field stars and globular clusters (GCs) obtained using Keck-DEIMOS/LRIS and Magellan-IMACS. Within two effective radii, the bulge (as traced by the stars and metal-rich GCs) is flattened and rotates rapidly (v/σ ∼> 1.5). At larger radii, the rotation declines dramatically to v/σ ∼ 0.7, but remains well aligned with the inner regions. The radial decrease in characteristic metallicity of both the metal-rich and metal-poor GC subpopulations produces strong gradients with power-law slopes of -0.17 ± 0.04 and -0.38 ± 0.06 dex dex -1 , respectively. We argue that this pattern is not naturally explained by a binary major merger, but instead by a two-phase assembly process where the inner regions have formed in an early violent, dissipative phase, followed by the protracted growth of the outer parts via minor mergers with typical mass ratios of ∼15-20:1.

Gamma Ray Imaging System (GRIS) GammaCam trademark. Final report, January 3, 1994 - May 31, 1996

International Nuclear Information System (INIS)

1996-01-01

This report describes the activities undertaken during the development of the Gamma Ray Imaging System (GRIS) program now referred to as the GammaCam trademark. The purpose of this program is to develop a 2-dimensional imaging system for gamma-ray energy scenes that may be present in nuclear power plants. The report summarizes the overall accomplishments of the program and the most recent GammaCam measurements made at LANL and Estonia. The GammaCam is currently available for sale from AIL Systems as an off-the-shelf instrument

Tools for Generating Useful Time-series Data from PhenoCam Images

Science.gov (United States)

Milliman, T. E.; Friedl, M. A.; Frolking, S.; Hufkens, K.; Klosterman, S.; Richardson, A. D.; Toomey, M. P.

2012-12-01

The PhenoCam project (http://phenocam.unh.edu/) is tasked with acquiring, processing, and archiving digital repeat photography to be used for scientific studies of vegetation phenological processes. Over the past 5 years the PhenoCam project has collected over 2 million time series images for a total over 700 GB of image data. Several papers have been published describing derived "vegetation indices" (such as green-chromatic-coordinate or gcc) which can be compared to standard measures such as NDVI or EVI. Imagery from our archive is available for download but converting series of images for a particular camera into useful scientific data, while simple in principle, is complicated by a variety of factors. Cameras are often exposed to harsh weather conditions (high wind, rain, ice, snow pile up), which result in images where the field of view (FOV) is partially obscured or completely blocked for periods of time. The FOV can also change for other reasons (mount failures, tower maintenance, etc.) Some of the relatively inexpensive cameras that are being used can also temporarily lose color balance or exposure controls resulting in loss of imagery. All these factors negatively influence the automated analysis of the image time series making this a non-trivial task. Here we discuss the challenges of processing PhenoCam image time-series for vegetation monitoring and the associated data management tasks. We describe our current processing framework and a simple standardized output format for the resulting time-series data. The time-series data in this format will be generated for specific "regions of interest" (ROI's) for each of the cameras in the PhenoCam network. This standardized output (which will be updated daily) can be considered 'the pulse' of a particular camera and will provide a default phenological dynamic for said camera. The time-series data can also be viewed as a higher level product which can be used to generate "vegetation indices", like gcc, for

Subaru High-z Exploration of Low-Luminosity Quasars (SHELLQs). III. Star formation properties of the host galaxies at z ≳ 6 studied with ALMA

Science.gov (United States)

Izumi, Takuma; Onoue, Masafusa; Shirakata, Hikari; Nagao, Tohru; Kohno, Kotaro; Matsuoka, Yoshiki; Imanishi, Masatoshi; Strauss, Michael A.; Kashikawa, Nobunari; Schulze, Andreas; Silverman, John D.; Fujimoto, Seiji; Harikane, Yuichi; Toba, Yoshiki; Umehata, Hideki; Nakanishi, Kouichiro; Greene, Jenny E.; Tamura, Yoichi; Taniguchi, Akio; Yamaguchi, Yuki; Goto, Tomotsugu; Hashimoto, Yasuhiro; Ikarashi, Soh; Iono, Daisuke; Iwasawa, Kazushi; Lee, Chien-Hsiu; Makiya, Ryu; Minezaki, Takeo; Tang, Ji-Jia

2018-04-01

We present our ALMA Cycle 4 measurements of the [C II] emission line and the underlying far-infrared (FIR) continuum emission from four optically low-luminosity (M1450 > -25) quasars at z ≳ 6 discovered by the Subaru Hyper Suprime Cam (HSC) survey. The [C II] line and FIR continuum luminosities lie in the ranges L_[C II] = (3.8-10.2)× 108 L_{⊙} and LFIR = (1.2-2.0) × 1011 L_{⊙}, which are at least one order of magnitude smaller than those of optically-luminous quasars at z ≳ 6. We estimate the star formation rates (SFRs) of our targets as ≃ 23-40 M_{⊙} yr-1. Their line and continuum-emitting regions are marginally resolved, and found to be comparable in size to those of optically-luminous quasars, indicating that their SFR or likely gas mass surface densities (key controlling parameter of mass accretion) are accordingly different. The L_[C II]/L_FIR ratios of the hosts, ≃ (2.2-8.7) × 10-3, are fully consistent with local star-forming galaxies. Using the [C II] dynamics, we derived their dynamical masses within a radius of 1.5-2.5 kpc as ≃ (1.4-8.2) × 1010 M_{⊙}. By interpreting these masses as stellar ones, we suggest that these faint quasar hosts are on or even below the star-forming main sequence at z ˜ 6, i.e., they appear to be transforming into quiescent galaxies. This is in contrast to the optically-luminous quasars at those redshifts, which show starburst-like properties. Finally, we find that the ratios of black hole mass to host galaxy dynamical mass of most of the low-luminosity quasars, including the HSC ones, are consistent with the local value. The mass ratios of the HSC quasars can be reproduced by a semi-analytical model that assumes merger-induced black hole host galaxy evolution.

Weak lensing study of 16 DAFT/FADA clusters: Substructures and filaments

Science.gov (United States)

Martinet, Nicolas; Clowe, Douglas; Durret, Florence; Adami, Christophe; Acebrón, Ana; Hernandez-García, Lorena; Márquez, Isabel; Guennou, Loic; Sarron, Florian; Ulmer, Mel

2016-05-01

While our current cosmological model places galaxy clusters at the nodes of a filament network (the cosmic web), we still struggle to detect these filaments at high redshifts. We perform a weak lensing study for a sample of 16 massive, medium-high redshift (0.4 DAFT/FADA survey, which are imaged in at least three optical bands with Subaru/Suprime-Cam or CFHT/MegaCam. We estimate the cluster masses using an NFW fit to the shear profile measured in a KSB-like method, adding our contribution to the calibration of the observable-mass relation required for cluster abundance cosmological studies. We compute convergence maps and select structures within these maps, securing their detection with noise resampling techniques. Taking advantage of the large field of view of our data, we study cluster environment, adding information from galaxy density maps at the cluster redshift and from X-ray images when available. We find that clusters show a large variety of weak lensing maps at large scales and that they may all be embedded in filamentary structures at megaparsec scale. We classify these clusters in three categories according to the smoothness of their weak lensing contours and to the amount of substructures: relaxed (~7%), past mergers (~21.5%), and recent or present mergers (~71.5%). The fraction of clusters undergoing merging events observationally supports the hierarchical scenario of cluster growth, and implies that massive clusters are strongly evolving at the studied redshifts. Finally, we report the detection of unusually elongated structures in CLJ0152, MACSJ0454, MACSJ0717, A851, BMW1226, MACSJ1621, and MS1621. This study is based on observations obtained with MegaCam, a joint project of CFHT and CEA/IRFU, at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii

From science to industrial technology. NewSUBARU's initiative

International Nuclear Information System (INIS)

Ando, A.

2004-01-01

The NewSUBARU synchrotron radiation facility is constructed to enhance domestic industries in Hyogo prefecture with high technology and to develop new light sources. NewSUBARU is now pushing up activities in industrial micro fabrication in the world and will make a breakthrough in commercial mass production with synchrotron radiation. The negative alpha-p operation of the storage ring gives good opportunities not only for new understandings of beam physics but also for coherent mm-wave light by very short electron bunches. (author)

Large Area Survey for z = 7 Galaxies in SDF and GOODS-N: Implications for Galaxy Formation and Cosmic Reionization

Science.gov (United States)

Ouchi, Masami; Mobasher, Bahram; Shimasaku, Kazuhiro; Ferguson, Henry C.; Fall, S. Michael; Ono, Yoshiaki; Kashikawa, Nobunari; Morokuma, Tomoki; Nakajima, Kimihiko; Okamura, Sadanori; Dickinson, Mark; Giavalisco, Mauro; Ohta, Kouji

2009-12-01

We present results of our large area survey for z'-band dropout galaxies at z = 7 in a 1568 arcmin2 sky area covering the SDF and GOODS-N fields. Combining our ultra-deep Subaru/Suprime-Cam z'- and y-band (λeff = 1 μm) images with legacy data of Subaru and Hubble Space Telescope, we have identified 22 bright z-dropout galaxies down to y = 26, one of which has a spectroscopic redshift of z = 6.96 determined from Lyα emission. The z = 7 luminosity function yields the best-fit Schechter parameters of phi* = 0.69+2.62 -0.55 × 10-3 Mpc-3, M*UV = -20.10 ± 0.76 mag, and α = -1.72 ± 0.65, and indicates a decrease from z = 6 at a >95% confidence level. This decrease is beyond the cosmic variance in our two fields, which is estimated to be a factor of lsim2. We have found that the cosmic star formation rate density drops from the peak at z = 2-3 to z = 7 roughly by a factor of ~10 but not larger than ~100. A comparison with the reionization models suggests either that the universe could not be totally ionized by only galaxies at z = 7, or more likely that properties of galaxies at z = 7 are different from those at low redshifts having, e.g., a larger escape fraction (gsim0.2), a lower metallicity, and/or a flatter initial mass function. Our SDF z-dropout galaxies appear to form 60 Mpc long filamentary structures, and the z = 6.96 galaxy with Lyα emission is located at the center of an overdense region consisting of four UV bright dropout candidates, which might suggest an existence of a well-developed ionized bubble at z = 7. Based on data obtained with the Subaru Telescope, the NASA/ESA Hubble Space Telescope (HST), and Spitzer Space Telescope. The Subaru Telescope is operated by the National Astronomical Observatory of Japan. HST is operated by the Association of Universities for Research in Astronomy (AURA), Inc., under NASA contract NAS5-26555. The Spitzer Space Telescope is operated by the Jet Propulsion Laboratory, California Institute of Technology under a

"Baby-Cam" and Researching with Infants: Viewer, Image and (Not) Knowing

Science.gov (United States)

Elwick, Sheena

2015-01-01

This article offers a methodological reflection on how "baby-cam" enhanced ethically reflective attitudes in a large-scale research project that set out to research with infants in Australian early childhood education and care settings. By juxtaposing digital images produced by two different digital-camera technologies and drawing on…

The HectoMAP Cluster Survey. I. redMaPPer Clusters

Science.gov (United States)

Sohn, Jubee; Geller, Margaret J.; Rines, Kenneth J.; Hwang, Ho Seong; Utsumi, Yousuke; Diaferio, Antonaldo

2018-04-01

We use the dense HectoMAP redshift survey to explore the properties of 104 redMaPPer cluster candidates. The redMaPPer systems in HectoMAP cover the full range of richness and redshift (0.08 systems included in the Subaru/Hyper Suprime-Cam public data release are bona fide clusters. The median number of spectroscopic members per cluster is ∼20. We include redshifts of 3547 member candidates listed in the redMaPPer catalog whether they are cluster members or not. We evaluate the redMaPPer membership probability spectroscopically. The purity (number of real systems) in redMaPPer exceeds 90% even at the lowest richness. Three massive galaxy clusters (M ∼ 2 × 1013 M ⊙) associated with X-ray emission in the HectoMAP region are not included in the public redMaPPer catalog with λ rich > 20, because they lie outside the cuts for this catalog.

The star formation history of the Sextans dwarf spheroidal galaxy: a true fossil of the pre-reionization era

Science.gov (United States)

Bettinelli, M.; Hidalgo, S. L.; Cassisi, S.; Aparicio, A.; Piotto, G.

2018-05-01

We present the star formation history (SFH) of the Sextans dwarf spheroidal galaxy based on deep archive B, I photometry taken with Suprime-Cam at Subaru telescope focusing our analysis on the inner region of the galaxy, fully located within the core radius. Within the errors of our SFH, we have not detected any metallicity gradient along the considered radial distance interval. As a main result of this work, we can state that the Sextans dwarf spheroidal stopped forming stars less than ˜1.3 Gyr after big bang in correspondence to the end of the reionization epoch. We have been able to constrain the duration of the main burst of star formation to ˜0.6 Gyr. From the calculation of the mechanical luminosity released from supernovae (SNe) during the brief episode of star formation, there are strong indications that SNe could have played an important role in the fate of Sextans, by removing almost completely the gas component, so preventing a prolonged star formation.

Development in High-Density Cobra Fiber Positioners for the Subaru Telescope's Prime Focus Spectrometer

Science.gov (United States)

Fisher, Charles D.; Braun, David F.; Kaluzny, Joel V.; Seiffert, Mic D.; Dekany, Richard G.; Ellis, Richard S.; Smith, Roger S.

2012-01-01

The Prime Focus Spectrograph (PFS) is a fiber fed multi-object spectrometer for the Subaru Telescope that will conduct a variety of targeted surveys for studies of dark energy, galaxy evolution, and galactic archaeology. The key to the instrument is a high density array of fiber positioners placed at the prime focus of the Subaru Telescope. The system, nicknamed "Cobra", will be capable of rapidly reconfiguring the array of 2394 optical fibers to the image positions of astronomical targets in the focal plane with high accuracy. The system uses 2394 individual "SCARA robot" mechanisms that are 7.7mm in diameter and use 2 piezo-electric rotary motors to individually position each of the optical fibers within its patrol region. Testing demonstrates that the Cobra positioner can be moved to within 5 micrometers of an astronomical target in 6 move iterations with a success rate of 95%. The Cobra system is a key aspect of PFS that will enable its unprecedented combination of high-multiplex factor and observing efficiency on the Subaru telescope. The requirements, design, and prototyping efforts for the fiber positioner system for the PFS are described here as are the plans for modular construction, assembly, integration, functional testing, and performance validation.

Near-Field Cosmology with Resolved Stellar Populations Around Local Volume LMC Stellar-Mass Galaxies

Science.gov (United States)

Carlin, Jeffrey L.; Sand, David J.; Willman, Beth; Brodie, Jean P.; Crnojevic, Denija; Forbes, Duncan; Hargis, Jonathan R.; Peter, Annika; Pucha, Ragadeepika; Romanowsky, Aaron J.; Spekkens, Kristine; Strader, Jay

2018-06-01

We discuss our ongoing observational program to comprehensively map the entire virial volumes of roughly LMC stellar mass galaxies at distances of ~2-4 Mpc. The MADCASH (Magellanic Analog Dwarf Companions And Stellar Halos) survey will deliver the first census of the dwarf satellite populations and stellar halo properties within LMC-like environments in the Local Volume. Our results will inform our understanding of the recent DES discoveries of dwarf satellites tentatively affiliated with the LMC/SMC system. This program has already yielded the discovery of the faintest known dwarf galaxy satellite of an LMC stellar-mass host beyond the Local Group, based on deep Subaru+HyperSuprimeCam imaging reaching ~2 magnitudes below its TRGB, and at least two additional candidate satellites. We will summarize the survey results and status to date, highlighting some challenges encountered and lessons learned as we process the data for this program through a prototype LSST pipeline. Our program will examine whether LMC stellar mass dwarfs have extended stellar halos, allowing us to assess the relative contributions of in-situ stars vs. merger debris to their stellar populations and halo density profiles. We outline the constraints on galaxy formation models that will be provided by our observations of low-mass galaxy halos and their satellites.

The Magellanic Analog Dwarf Companions and Stellar Halos (MADCASH) Survey: Near-Field Cosmology with Resolved Stellar Populations Around Local Volume LMC Stellar-Mass Galaxies

Science.gov (United States)

Carlin, Jeffrey L.; Sand, David J.; Willman, Beth; Brodie, Jean P.; Crnojevic, Denija; Peter, Annika; Price, Paul A.; Romanowsky, Aaron J.; Spekkens, Kristine; Strader, Jay

2017-01-01

We discuss the first results of our observational program to comprehensively map nearly the entire virial volumes of roughly LMC stellar mass galaxies at distances of ~2-4 Mpc. The MADCASH (Magellanic Analog Dwarf Companions And Stellar Halos) survey will deliver the first census of the dwarf satellite populations and stellar halo properties within LMC-like environments in the Local Volume. These will inform our understanding of the recent DES discoveries of dwarf satellites tentatively affiliated with the LMC/SMC system. We will detail our discovery of the faintest known dwarf galaxy satellite of an LMC stellar-mass host beyond the Local Group, based on deep Subaru+HyperSuprimeCam imaging reaching ~2 magnitudes below its TRGB. We will summarize the survey results and status to date, highlighting some challenges encountered and lessons learned as we process the data for this program through a prototype LSST pipeline. Our program will examine whether LMC stellar mass dwarfs have extended stellar halos, allowing us to assess the relative contributions of in-situ stars vs. merger debris to their stellar populations and halo density profiles. We outline the constraints on galaxy formation models that will be provided by our observations of low-mass galaxy halos and their satellites.

Searching for moving objects in HSC-SSP: Pipeline and preliminary results

Science.gov (United States)

Chen, Ying-Tung; Lin, Hsing-Wen; Alexandersen, Mike; Lehner, Matthew J.; Wang, Shiang-Yu; Wang, Jen-Hung; Yoshida, Fumi; Komiyama, Yutaka; Miyazaki, Satoshi

2018-01-01

The Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) is currently the deepest wide-field survey in progress. The 8.2 m aperture of the Subaru telescope is very powerful in detecting faint/small moving objects, including near-Earth objects, asteroids, centaurs and Tran-Neptunian objects (TNOs). However, the cadence and dithering pattern of the HSC-SSP are not designed for detecting moving objects, making it difficult to do so systematically. In this paper, we introduce a new pipeline for detecting moving objects (specifically TNOs) in a non-dedicated survey. The HSC-SSP catalogs are sliced into HEALPix partitions. Then, the stationary detections and false positives are removed with a machine-learning algorithm to produce a list of moving object candidates. An orbit linking algorithm and visual inspections are executed to generate the final list of detected TNOs. The preliminary results of a search for TNOs using this new pipeline on data from the first HSC-SSP data release (2014 March to 2015 November) present 231 TNO/Centaurs candidates. The bright candidates with Hr 5 show that the best-fitting slope of a single power law to absolute magnitude distribution is 0.77. The g - r color distribution of hot HSC-SSP TNOs indicates a bluer peak at g - r = 0.9, which is consistent with the bluer peak of the bimodal color distribution in literature.

SUBARU IMAGING OF ASYMMETRIC FEATURES IN A TRANSITIONAL DISK IN UPPER SCORPIUS

Energy Technology Data Exchange (ETDEWEB)

Mayama, S. [Center for the Promotion of Integrated Sciences, The Graduate University for Advanced Studies (SOKENDAI), Shonan International Village, Hayama-cho, Miura-gun, Kanagawa 240-0193 (Japan); Hashimoto, J.; Kusakabe, N.; Kuzuhara, M.; Takahashi, Y.; Akiyama, E. [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Muto, T. [Division of Liberal Arts, Kogakuin University, 1-24-2, Nishi-Shinjuku, Shinjuku-ku, Tokyo 163-8677 (Japan); Tsukagoshi, T.; Momose, M. [College of Science, Ibaraki University, 2-1-1 Bunkyo, Mito, Ibaraki 310-8512 (Japan); Kudo, T.; Egner, S. [Subaru Telescope, 650 North A' ohoku Place, Hilo, HI 96720 (United States); Dong, R.; Brandt, T. [Department of Astrophysical Sciences, Princeton University, NJ 08544 (United States); Fukagawa, M. [Department of Earth and Space Science, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043 (Japan); Takami, M. [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 106, Taiwan (China); Wisniewski, J. P. [H L Dodge Department of Physics and Astronomy, University of Oklahoma, 440 West Brooks St. Norman, OK 73019 (United States); Follette, K. [Department of Astronomy and Steward Observatory, The University of Arizona, 933 North Cherry Avenue, Rm. N204, Tucson, AZ 85721-0065 (United States); Abe, L. [Laboratoire Hippolyte Fizeau, UMR6525, Universite de Nice Sophia-Antipolis, 28, avenue Valrose, F-06108 Nice Cedex 02 (France); Brandner, W. [Max Planck Institute for Astronomy, Koenigstuhl 17, D-69117 Heidelberg (Germany); Carson, J., E-mail: mayama_satoshi@soken.ac.jp [Department of Physics and Astronomy, College of Charleston, 58 Coming Street, Charleston, SC 29424 (United States); and others

2012-12-01

We report high-resolution (0.07 arcsec) near-infrared polarized intensity images of the circumstellar disk around the star 2MASS J16042165-2130284 obtained with HiCIAO mounted on the Subaru 8.2 m telescope. We present our H-band data, which clearly exhibit a resolved, face-on disk with a large inner hole for the first time at infrared wavelengths. We detect the centrosymmetric polarization pattern in the circumstellar material as has been observed in other disks. Elliptical fitting gives the semimajor axis, semiminor axis, and position angle (P.A.) of the disk as 63 AU, 62 AU, and -14 Degree-Sign , respectively. The disk is asymmetric, with one dip located at P.A.s of {approx}85 Degree-Sign . Our observed disk size agrees well with a previous study of dust and CO emission at submillimeter wavelength with Submillimeter Array. Hence, the near-infrared light is interpreted as scattered light reflected from the inner edge of the disk. Our observations also detect an elongated arc (50 AU) extending over the disk inner hole. It emanates at the inner edge of the western side of the disk, extending inward first, then curving to the northeast. We discuss the possibility that the inner hole, the dip, and the arc that we have observed may be related to the existence of unseen bodies within the disk.

High-Resolution Mid-IR Imaging of Jupiter's Great Red Spot: Comparing Cassini, VLT and Subaru Observations

Science.gov (United States)

Fletcher, Leigh N.; Orton, G. S.; Yanamandra-Fisher, P.; Irwin, P. G. J.; Baines, K. H.; Edkins, E.; Line, M. R.; Mousis, O.; Parrish, P. D.; Vanzi, L.; Fuse, T.; Fujoyoshi, T.

2008-09-01

In the eight years since the Cassini fly-by of Jupiter, the spatial resolution of ground-based observations of Jupiter's giant anticyclonic storm systems (the Great Red Spot, Oval BA and others) using 8m-class telescopes has surpassed the resolution of the Cassini/CIRS maps. We present a time-series of mid-IR imaging of the Great Red Spot (GRS) and its environs from the VISIR instrument on the Very Large Telescope (UT3/Melipal) and the COMICS instrument on the Subaru telescope (Hawaii). The NEMESIS optimal-estimation retrieval algorithm (Irwin et al., 2008) is used to analyse both the 7-25 micron filtered imaging from 2005-2008 and Cassini/CIRS 7-16 micron data from 2000. We demonstrate the ability to map temperatures in the 100-400 mbar range, NH3, aerosol opacity and the para-H2 fraction from the filtered imaging. Furthermore, the Cassini/CIRS spectra are used to map the PH3 mole fraction around the GRS. The thermal field, gaseous composition and aerosol distribution are used as diagnostics for the atmospheric motion associated with the GRS. Changes in the atmospheric state in response to close encounters with Oval BA and other vortices will be assessed. These results will be discussed in light of their implications for the planning of the Europa-Jupiter System Mission.

Systematic Identification of LAEs for Visible Exploration and Reionization Research Using Subaru HSC (SILVERRUSH). I. Program strategy and clustering properties of ˜2000 Lyα emitters at z = 6-7 over the 0.3-0.5 Gpc2 survey area

Science.gov (United States)

Ouchi, Masami; Harikane, Yuichi; Shibuya, Takatoshi; Shimasaku, Kazuhiro; Taniguchi, Yoshiaki; Konno, Akira; Kobayashi, Masakazu; Kajisawa, Masaru; Nagao, Tohru; Ono, Yoshiaki; Inoue, Akio K.; Umemura, Masayuki; Mori, Masao; Hasegawa, Kenji; Higuchi, Ryo; Komiyama, Yutaka; Matsuda, Yuichi; Nakajima, Kimihiko; Saito, Tomoki; Wang, Shiang-Yu

2018-01-01

We present the SILVERRUSH program strategy and clustering properties investigated with ˜2000 Lyα emitters (LAEs) at z = 5.7 and 6.6 found in the early data of the Hyper Suprime-Cam (HSC) Subaru Strategic Program survey exploiting the carefully designed narrow-band filters. We derive angular correlation functions with the unprecedentedly large samples of LAEs at z = 6-7 over the large total area of 14-21 deg2 corresponding to 0.3-0.5 comoving Gpc2. We obtain the average large-scale bias values of bavg = 4.1 ± 0.2 (4.5 ± 0.6) at z = 5.7 (z = 6.6) for ≳ L* LAEs, indicating a weak evolution of LAE clustering from z = 5.7 to 6.6. We compare the LAE clustering results with two independent theoretical models that suggest an increase of an LAE clustering signal by the patchy ionized bubbles at the epoch of reionization (EoR), and estimate the neutral hydrogen fraction to be x_{H I}=0.15^{+0.15}_{-0.15} at z = 6.6. Based on the halo occupation distribution models, we find that the ≳ L* LAEs are hosted by dark-matter halos with an average mass of log ( /M_⊙ ) =11.1^{+0.2}_{-0.4} (10.8^{+0.3}_{-0.5}) at z = 5.7 (6.6) with a Lyα duty cycle of 1% or less, where the results of z = 6.6 LAEs may be slightly biased, due to the increase of the clustering signal at the EoR. Our clustering analysis reveals the low-mass nature of ≳ L* LAEs at z = 6-7, and that these LAEs probably evolve into massive super-L* galaxies in the present-day universe.

Results from the Splash Survey: Spectroscopic and Photometric Landscape of Andromeda's Stellar Halo

Science.gov (United States)

Guhathakurta, Puragra; SPLASH Collaboration

2009-01-01

Detailed studies of nearby galaxies provide vital clues about their formation and evolutionary history. This "fossil record" approach is complementary to direct look-back studies of distant galaxies. Our Galaxy and the Andromeda spiral galaxy (M31) have long been cornerstones in the former category. M31 provides an external perspective on a large galaxy similar to our own and yet is close enough to allow detailed studies of individual stars. In my talk, I will present results from the SPLASH collaboration: Spectroscopic and Photometric Landscape of Andromeda's Stellar Halo. The collective data set from this large international team includes thousands of Keck/DEIMOS spectra of individual red giant branch stars, ground-based deep wide-field imaging and photometry with KPNO/Mosaic, CFHT/MegaCam, and Subaru/Suprime-Cam, and ultra-deep pencil-beam probes with HST/ACS imaging reaching below the main-sequence turnoff. Our recent discovery of an extended stellar halo in M31 (R > 150 kpc) shows that most previous studies of its spheroid have been sampling its inner bulge-like spheroidal component, not its halo. In my talk I will touch upon several related topics related to the general theme of hierarchical galaxy formation including: M31's global structure and subcomponents (halo, bulge/central bar, and disk), stellar dynamics, statistical properties of substructure, detailed chemical abundance measurements, detailed forensic reconstruction of recent collision events, dwarf satellites as tracers and building blocks of larger galaxies, and empirical constraints on the tangential motion of the M31 system. I will also discuss recent results on the chemical abundance of the lowest luminosity Galactic satellites (recently discovered by SDSS) and implications for the formation of the Milky Way halo. This research was supported by funds from the National Science Foundation, NASA, and the Institute for Geophysics and Planetary Physics.

Cloud top structure of Venus revealed by Subaru/COMICS mid-infrared images

Science.gov (United States)

Sato, T. M.; Sagawa, H.; Kouyama, T.; Mitsuyama, K.; Satoh, T.; Ohtsuki, S.; Ueno, M.; Kasaba, Y.; Nakamura, M.; Imamura, T.

2014-11-01

We have investigated the cloud top structure of Venus by analyzing ground-based images taken at the mid-infrared wavelengths of 8.66 μm and 11.34 μm. Venus at a solar phase angle of ∼90°, with the morning terminator in view, was observed by the Cooled Mid-Infrared Camera and Spectrometer (COMICS), mounted on the 8.2-m Subaru Telescope, during the period October 25-29, 2007. The disk-averaged brightness temperatures for the observation period are ∼230 K and ∼238 K at 8.66 μm and 11.34 μm, respectively. The obtained images with good signal-to-noise ratio and with high spatial resolution (∼200 km at the sub-observer point) provide several important findings. First, we present observational evidence, for the first time, of the possibility that the westward rotation of the polar features (the hot polar spots and the surrounding cold collars) is synchronized between the northern and southern hemispheres. Second, after high-pass filtering, the images reveal that streaks and mottled and patchy patterns are distributed over the entire disk, with typical amplitudes of ∼0.5 K, and vary from day to day. The detected features, some of which are similar to those seen in past UV images, result from inhomogeneities of both the temperature and the cloud top altitude. Third, the equatorial center-to-limb variations of brightness temperatures have a systematic day-night asymmetry, except those on October 25, that the dayside brightness temperatures are higher than the nightside brightness temperatures by 0-4 K under the same viewing geometry. Such asymmetry would be caused by the propagation of the migrating semidiurnal tide. Finally, by applying the lapse rates deduced from previous studies, we demonstrate that the equatorial center-to-limb curves in the two spectral channels give access to two parameters: the cloud scale height H and the cloud top altitude zc. The acceptable models for data on October 25 are obtained at H = 2.4-4.3 km and zc = 66-69 km; this supports

Fringing in MonoCam Y4 filter images

International Nuclear Information System (INIS)

Brooks, J.; Nomerotski, A.; Fisher-Levine, M.

2017-01-01

We study the fringing patterns observed in MonoCam, a camera with a single Large Synoptic Survey Telescope (LSST) CCD sensor. Images were taken at the U.S. Naval Observatory in Flagstaff, Arizona (NOFS) employing its 1.3 m telescope and an LSST y 4 filter. Fringing occurs due to the reflection of infrared light (700 nm or larger) from the bottom surface of the CCD which constructively or destructively interferes with the incident light to produce a net ''fringe'' pattern which is superimposed on all images taken. Emission lines from the atmosphere, dominated by hydroxyl (OH) spectra, can change in their relative intensities as the night goes on, producing different fringe patterns in the images taken. We found through several methods that the general shape of the fringe patterns remained constant, though with slight changes in the amplitude and phase of the fringes. We also found that a superposition of fringes from two monochromatic lines taken in the lab offered a reasonable description of the sky data.

The redshift distribution of cosmological samples: a forward modeling approach

Energy Technology Data Exchange (ETDEWEB)

Herbel, Jörg; Kacprzak, Tomasz; Amara, Adam; Refregier, Alexandre; Bruderer, Claudio; Nicola, Andrina, E-mail: joerg.herbel@phys.ethz.ch, E-mail: tomasz.kacprzak@phys.ethz.ch, E-mail: adam.amara@phys.ethz.ch, E-mail: alexandre.refregier@phys.ethz.ch, E-mail: claudio.bruderer@phys.ethz.ch, E-mail: andrina.nicola@phys.ethz.ch [Institute for Astronomy, Department of Physics, ETH Zürich, Wolfgang-Pauli-Strasse 27, 8093 Zürich (Switzerland)

2017-08-01

Determining the redshift distribution n ( z ) of galaxy samples is essential for several cosmological probes including weak lensing. For imaging surveys, this is usually done using photometric redshifts estimated on an object-by-object basis. We present a new approach for directly measuring the global n ( z ) of cosmological galaxy samples, including uncertainties, using forward modeling. Our method relies on image simulations produced using \\textsc(UFig) (Ultra Fast Image Generator) and on ABC (Approximate Bayesian Computation) within the MCCL (Monte-Carlo Control Loops) framework. The galaxy population is modeled using parametric forms for the luminosity functions, spectral energy distributions, sizes and radial profiles of both blue and red galaxies. We apply exactly the same analysis to the real data and to the simulated images, which also include instrumental and observational effects. By adjusting the parameters of the simulations, we derive a set of acceptable models that are statistically consistent with the data. We then apply the same cuts to the simulations that were used to construct the target galaxy sample in the real data. The redshifts of the galaxies in the resulting simulated samples yield a set of n ( z ) distributions for the acceptable models. We demonstrate the method by determining n ( z ) for a cosmic shear like galaxy sample from the 4-band Subaru Suprime-Cam data in the COSMOS field. We also complement this imaging data with a spectroscopic calibration sample from the VVDS survey. We compare our resulting posterior n ( z ) distributions to the one derived from photometric redshifts estimated using 36 photometric bands in COSMOS and find good agreement. This offers good prospects for applying our approach to current and future large imaging surveys.

The redshift distribution of cosmological samples: a forward modeling approach

Science.gov (United States)

Herbel, Jörg; Kacprzak, Tomasz; Amara, Adam; Refregier, Alexandre; Bruderer, Claudio; Nicola, Andrina

2017-08-01

Determining the redshift distribution n(z) of galaxy samples is essential for several cosmological probes including weak lensing. For imaging surveys, this is usually done using photometric redshifts estimated on an object-by-object basis. We present a new approach for directly measuring the global n(z) of cosmological galaxy samples, including uncertainties, using forward modeling. Our method relies on image simulations produced using \\textsc{UFig} (Ultra Fast Image Generator) and on ABC (Approximate Bayesian Computation) within the MCCL (Monte-Carlo Control Loops) framework. The galaxy population is modeled using parametric forms for the luminosity functions, spectral energy distributions, sizes and radial profiles of both blue and red galaxies. We apply exactly the same analysis to the real data and to the simulated images, which also include instrumental and observational effects. By adjusting the parameters of the simulations, we derive a set of acceptable models that are statistically consistent with the data. We then apply the same cuts to the simulations that were used to construct the target galaxy sample in the real data. The redshifts of the galaxies in the resulting simulated samples yield a set of n(z) distributions for the acceptable models. We demonstrate the method by determining n(z) for a cosmic shear like galaxy sample from the 4-band Subaru Suprime-Cam data in the COSMOS field. We also complement this imaging data with a spectroscopic calibration sample from the VVDS survey. We compare our resulting posterior n(z) distributions to the one derived from photometric redshifts estimated using 36 photometric bands in COSMOS and find good agreement. This offers good prospects for applying our approach to current and future large imaging surveys.

The redshift distribution of cosmological samples: a forward modeling approach

International Nuclear Information System (INIS)

Herbel, Jörg; Kacprzak, Tomasz; Amara, Adam; Refregier, Alexandre; Bruderer, Claudio; Nicola, Andrina

2017-01-01

Determining the redshift distribution n ( z ) of galaxy samples is essential for several cosmological probes including weak lensing. For imaging surveys, this is usually done using photometric redshifts estimated on an object-by-object basis. We present a new approach for directly measuring the global n ( z ) of cosmological galaxy samples, including uncertainties, using forward modeling. Our method relies on image simulations produced using \\textsc(UFig) (Ultra Fast Image Generator) and on ABC (Approximate Bayesian Computation) within the MCCL (Monte-Carlo Control Loops) framework. The galaxy population is modeled using parametric forms for the luminosity functions, spectral energy distributions, sizes and radial profiles of both blue and red galaxies. We apply exactly the same analysis to the real data and to the simulated images, which also include instrumental and observational effects. By adjusting the parameters of the simulations, we derive a set of acceptable models that are statistically consistent with the data. We then apply the same cuts to the simulations that were used to construct the target galaxy sample in the real data. The redshifts of the galaxies in the resulting simulated samples yield a set of n ( z ) distributions for the acceptable models. We demonstrate the method by determining n ( z ) for a cosmic shear like galaxy sample from the 4-band Subaru Suprime-Cam data in the COSMOS field. We also complement this imaging data with a spectroscopic calibration sample from the VVDS survey. We compare our resulting posterior n ( z ) distributions to the one derived from photometric redshifts estimated using 36 photometric bands in COSMOS and find good agreement. This offers good prospects for applying our approach to current and future large imaging surveys.

The Double Galaxy Cluster A2465. III. X-Ray and Weak-lensing Observations

Science.gov (United States)

Wegner, Gary A.; Umetsu, Keiichi; Molnar, Sandor M.; Nonino, Mario; Medezinski, Elinor; Andrade-Santos, Felipe; Bogdan, Akos; Lovisari, Lorenzo; Forman, William R.; Jones, Christine

2017-07-01

We report Chandra X-ray observations and optical weak-lensing measurements from Subaru/Suprime-Cam images of the double galaxy cluster A2465 (z = 0.245). The X-ray brightness data are fit to a β model to obtain the radial gas density profiles of the northeast (NE) and southwest (SW) subcomponents, which are seen to differ in structure. We determine core radii, central temperatures, the gas masses within r 500c, and the total masses for the broader NE and sharper SW components assuming hydrostatic equilibrium. There is no large X-ray excess between the two components. The central entropy of the NE subcluster is about two times higher than the SW. Along with its structural properties and an apparent radio halo that is a sign of a merger, this suggests that the NE component has undergone merging on its own. The weak-lensing analysis gives virial masses for each substructure, which compare well with earlier dynamical results. The derived outer mass contours of the SW sub-component from weak lensing are more irregular and extended than those of the NE. Although there is a weak enhancement and small offsets between X-ray gas and mass centers from weak lensing, the lack of large amounts of gas between the two subclusters indicates that A2465 is in a pre-merger state. We discuss star formation enhancement in this system resulting from its dynamics and shock-induced star formation scenarios. A dynamical model that is consistent with the observed cluster data, based on the FLASH program and the radial infall model, is constructed, where the subclusters currently separated by ˜1.2 Mpc are approaching each other at ˜2000 km s-1 and will meet in ˜0.4 Gyr. Based in part on data collected at the Subaru Telescope, which is operated by the National Astronomical Society of Japan.

Lyman Break Galaxies at z ≈ 1.8-2.8: GALEX/NUV Imaging of the Subaru Deep Field

Science.gov (United States)

Ly, Chun; Malkan, Matthew A.; Treu, Tommaso; Woo, Jong-Hak; Currie, Thayne; Hayashi, Masao; Kashikawa, Nobunari; Motohara, Kentaro; Shimasaku, Kazuhiro; Yoshida, Makiko

2009-06-01

A photometric sample of ~8000 V dropouts at 1.5 University of California, and NASA), the Subaru Telescope (operated by the National Astronomical Observatory of Japan), and the MMT Observatory (a joint facility of the University of Arizona and the Smithsonian Institution).

Gender differences in autobiographical memory for everyday events: retrieval elicited by SenseCam images versus verbal cues.

Science.gov (United States)

St Jacques, Peggy L; Conway, Martin A; Cabeza, Roberto

2011-10-01

Gender differences are frequently observed in autobiographical memory (AM). However, few studies have investigated the neural basis of potential gender differences in AM. In the present functional MRI (fMRI) study we investigated gender differences in AMs elicited using dynamic visual images vs verbal cues. We used a novel technology called a SenseCam, a wearable device that automatically takes thousands of photographs. SenseCam differs considerably from other prospective methods of generating retrieval cues because it does not disrupt the ongoing experience. This allowed us to control for potential gender differences in emotional processing and elaborative rehearsal, while manipulating how the AMs were elicited. We predicted that males would retrieve more richly experienced AMs elicited by the SenseCam images vs the verbal cues, whereas females would show equal sensitivity to both cues. The behavioural results indicated that there were no gender differences in subjective ratings of reliving, importance, vividness, emotion, and uniqueness, suggesting that gender differences in brain activity were not due to differences in these measures of phenomenological experience. Consistent with our predictions, the fMRI results revealed that males showed a greater difference in functional activity associated with the rich experience of SenseCam vs verbal cues, than did females.

STELLAR POPULATIONS OF Lyα EMITTERS AT z ∼ 6-7: CONSTRAINTS ON THE ESCAPE FRACTION OF IONIZING PHOTONS FROM GALAXY BUILDING BLOCKS

International Nuclear Information System (INIS)

Ono, Yoshiaki; Shimasaku, Kazuhiro; Okamura, Sadanori; Masami Ouchi; Dunlop, James; Farrah, Duncan; McLure, Ross

2010-01-01

We investigate the stellar populations of Lyα emitters (LAEs) at z = 5.7 and 6.6 in a 0.65 deg 2 sky of the Subaru/XMM-Newton Deep Survey (SXDS) Field, using deep images taken with the Subaru/Suprime-Cam, United Kingdom Infrared Telescope/Wide Field Infrared Camera, and Spitzer/Infrared Array Camera (IRAC). We produce stacked multiband images at each redshift from 165 (z = 5.7) and 91 (z = 6.6) IRAC-undetected objects to derive typical spectral energy distributions (SEDs) of z ∼ 6-7 LAEs for the first time. The stacked LAEs have as blue UV continua as the Hubble Space Telescope (HST)/Wide Field Camera 3 (WFC3) z-dropout galaxies of similar M UV , with a spectral slope β ∼ -3, but at the same time they have red UV-to-optical colors with detection in the 3.6 μm band. Using SED fitting we find that the stacked LAEs have low stellar masses of ∼(3-10) x 10 7 M sun , very young ages of ∼1-3 Myr, negligible dust extinction, and strong nebular emission from the ionized interstellar medium, although the z = 6.6 object is fitted similarly well with high-mass models without nebular emission; inclusion of nebular emission reproduces the red UV-to-optical colors while keeping the UV colors sufficiently blue. We infer that typical LAEs at z ∼ 6-7 are building blocks of galaxies seen at lower redshifts. We find a tentative decrease in the Lyα escape fraction from z = 5.7 to 6.6, which may imply an increase in the intergalactic medium neutral fraction. From the minimum contribution of nebular emission required to fit the observed SEDs, we place an upper limit on the escape fraction of ionizing photons of f ion esc ∼ 0.6 at z = 5.7 and ∼0.9 at z = 6.6. We also compare the stellar populations of our LAEs with those of stacked HST/WFC3 z-dropout galaxies.

Subaru/SCExAO First-light Direct Imaging of a Young Debris Disk around HD 36546

Energy Technology Data Exchange (ETDEWEB)

Currie, Thayne; Guyon, Olivier; Kudo, Tomoyuki; Jovanovic, Nemanja; Lozi, Julien [National Astronomical Observatory of Japan, Subaru Telescope, National Institutes of Natural Sciences, Hilo, HI 96720 (United States); Tamura, Motohide; Kuzuhara, Masayuki [Astrobiology Center, National Institutes of Natural Sciences, 2-21-1 Osawa, Mitaka, Tokyo (Japan); Schlieder, Joshua E. [IPAC-NExScI, Mail Code 100-22, Caltech, 1200 E. California Boulevard, Pasadena, CA 91125 (United States); Brandt, Timothy D. [Astrophysics Department, Institute for Advanced Study, Princeton, NJ (United States); Kuhn, Jonas [Institute for Astronomy, ETH-Zurich, Wolfgang-Pauli-Str. 27, 8093 Zurich (Switzerland); Serabyn, Eugene; Singh, Garima [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA (United States); Janson, Markus [Department of Astronomy, Stockholm University, AlbaNova University Center, SE-106 91 Stockholm (Sweden); Carson, Joseph [Department of Physics and Astronomy, College of Charleston, 66 George Street, Charleston, SC (United States); Groff, Tyler; Kasdin, N. Jeremy [Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ (United States); McElwain, Michael W.; Grady, Carol [Exoplanets and Stellar Astrophysics Laboratory, Code 667, NASA-Goddard Space Flight Center, Greenbelt, MD (United States); Uyama, Taichi [Department of Astronomy, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo (Japan); Akiyama, Eiji [Chile Observatory, National Astronomical Observatory of Japan, Osawa, Mitaka, Tokyo (Japan); and others

2017-02-10

We present H -band scattered light imaging of a bright debris disk around the A0 star HD 36546 obtained from the Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) system with data recorded by the HiCIAO camera using the vector vortex coronagraph. SCExAO traces the disk from r ∼ 0.″3 to r ∼1″ (34–114 au). The disk is oriented in a near east–west direction (PA ∼ 75°), is inclined by i ∼ 70°–75°, and is strongly forward-scattering (g > 0.5). It is an extended disk rather than a sharp ring; a second, diffuse dust population extends from the disk’s eastern side. While HD 36546 intrinsic properties are consistent with a wide age range (t ∼ 1–250 Myr), its kinematics and analysis of coeval stars suggest a young age (3–10 Myr) and a possible connection to Taurus-Auriga’s star formation history. SCExAO’s planet-to-star contrast ratios are comparable to the first-light Gemini Planet Imager contrasts; for an age of 10 Myr, we rule out planets with masses comparable to HR 8799 b beyond a projected separation of 23 au. A massive icy planetesimal disk or an unseen super-Jovian planet at r > 20 au may explain the disk’s visibility. The HD 36546 debris disk may be the youngest debris disk yet imaged, is the first newly identified object from the now-operational SCExAO extreme AO system, is ideally suited for spectroscopic follow-up with SCExAO/CHARIS in 2017, and may be a key probe of icy planet formation and planet–disk interactions.

Subaru/SCExAO First-light Direct Imaging of a Young Debris Disk around HD 36546

International Nuclear Information System (INIS)

Currie, Thayne; Guyon, Olivier; Kudo, Tomoyuki; Jovanovic, Nemanja; Lozi, Julien; Tamura, Motohide; Kuzuhara, Masayuki; Schlieder, Joshua E.; Brandt, Timothy D.; Kuhn, Jonas; Serabyn, Eugene; Singh, Garima; Janson, Markus; Carson, Joseph; Groff, Tyler; Kasdin, N. Jeremy; McElwain, Michael W.; Grady, Carol; Uyama, Taichi; Akiyama, Eiji

2017-01-01

We present H -band scattered light imaging of a bright debris disk around the A0 star HD 36546 obtained from the Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) system with data recorded by the HiCIAO camera using the vector vortex coronagraph. SCExAO traces the disk from r ∼ 0.″3 to r ∼1″ (34–114 au). The disk is oriented in a near east–west direction (PA ∼ 75°), is inclined by i ∼ 70°–75°, and is strongly forward-scattering (g > 0.5). It is an extended disk rather than a sharp ring; a second, diffuse dust population extends from the disk’s eastern side. While HD 36546 intrinsic properties are consistent with a wide age range (t ∼ 1–250 Myr), its kinematics and analysis of coeval stars suggest a young age (3–10 Myr) and a possible connection to Taurus-Auriga’s star formation history. SCExAO’s planet-to-star contrast ratios are comparable to the first-light Gemini Planet Imager contrasts; for an age of 10 Myr, we rule out planets with masses comparable to HR 8799 b beyond a projected separation of 23 au. A massive icy planetesimal disk or an unseen super-Jovian planet at r > 20 au may explain the disk’s visibility. The HD 36546 debris disk may be the youngest debris disk yet imaged, is the first newly identified object from the now-operational SCExAO extreme AO system, is ideally suited for spectroscopic follow-up with SCExAO/CHARIS in 2017, and may be a key probe of icy planet formation and planet–disk interactions.

Multifunctional nanoparticle-EpCAM aptamer bioconjugates: a paradigm for targeted drug delivery and imaging in cancer therapy.

Science.gov (United States)

Das, Manasi; Duan, Wei; Sahoo, Sanjeeb K

2015-02-01

The promising proposition of multifunctional nanoparticles for cancer diagnostics and therapeutics has inspired the development of theranostic approach for improved cancer therapy. Moreover, active targeting of drug carrier to specific target site is crucial for providing efficient delivery of therapeutics and imaging agents. In this regard, the present study investigates the theranostic capabilities of nutlin-3a loaded poly (lactide-co-glycolide) nanoparticles, functionalized with a targeting ligand (EpCAM aptamer) and an imaging agent (quantum dots) for cancer therapy and bioimaging. A wide spectrum of in vitro analysis (cellular uptake study, cytotoxicity assay, cell cycle and apoptosis analysis, apoptosis associated proteins study) revealed superior therapeutic potentiality of targeted NPs over other formulations in EpCAM expressing cells. Moreover, our nanotheranostic system served as a superlative bio-imaging modality both in 2D monolayer culture and tumor spheroid model. Our result suggests that, these aptamer-guided multifunctional NPs may act as indispensable nanotheranostic approach toward cancer therapy. This study investigated the theranostic capabilities of nutlin-3a loaded poly (lactide-co-glycolide) nanoparticles functionalized with a targeting ligand (EpCAM aptamer) and an imaging agent (quantum dots) for cancer therapy and bioimaging. It was concluded that the studied multifunctional targeted nanoparticle may become a viable and efficient approach in cancer therapy. Copyright © 2015 Elsevier Inc. All rights reserved.

SenseCam reminiscence and action recall in memory-unimpaired people.

Science.gov (United States)

Seamon, John G; Moskowitz, Tacie N; Swan, Ashley E; Zhong, Boyuan; Golembeski, Amy; Liong, Christopher; Narzikul, Alexa C; Sosan, Olumide A

2014-01-01

Case studies of memory-impaired individuals consistently show that reminiscing with SenseCam images enhances event recall. This exploratory study examined whether a similar benefit would occur for the consolidation of memories in memory-unimpaired people. We tested delayed recall for atypical actions observed on a lengthy walk. Participants used SenseCam, a diary, or no external memory aid while walking, followed by reminiscence with SenseCam images, diary entries, or no aid, either alone (self-reminiscence) or with the experimenter (social reminiscence). One week later, when tested without SenseCam images or diary entries, prior social reminiscence produced greater recall than self-reminiscence, but there were no differences between memory aid conditions for action free recall or action order recall. When methodological variables were controlled, there was no recall advantage for SenseCam reminiscence with memory-unimpaired participants. The case studies and present study differ in multiple ways, making direct comparisons problematic. SenseCam is a valuable aid to the memory impaired, but its mnemonic value for non-clinical populations remains to be determined.

EpCAM as multi-tumour target for near-infrared fluorescence guided surgery

International Nuclear Information System (INIS)

Driel, P. B. A. A. van; Boonstra, M. C.; Prevoo, H. A. J. M.; Giessen, M. van de; Snoeks, T. J. A.; Tummers, Q. R. J. G.; Keereweer, S.; Cordfunke, R. A.; Fish, A.; Eendenburg, J. D. H. van; Lelieveldt, B. P. F.; Dijkstra, J.; Velde, C. J. H. van de; Kuppen, P. J. K.; Vahrmeijer, A. L.; Löwik, C. W. G. M.; Sier, C. F. M.

2016-01-01

Evaluation of resection margins during cancer surgery can be challenging, often resulting in incomplete tumour removal. Fluorescence-guided surgery (FGS) aims to aid the surgeon to visualize tumours and resection margins during surgery. FGS relies on a clinically applicable imaging system in combination with a specific tumour-targeting contrast agent. In this study EpCAM (epithelial cell adhesion molecule) is evaluated as target for FGS in combination with the novel Artemis imaging system. The NIR fluorophore IRDye800CW was conjugated to the well-established EpCAM specific monoclonal antibody 323/A3 and an isotype IgG1 as control. The anti-EpCAM/800CW conjugate was stable in serum and showed preserved binding capacity as evaluated on EpCAM positive and negative cell lines, using flow cytometry and cell-based plate assays. Four clinically relevant orthotopic tumour models, i.e. colorectal cancer, breast cancer, head and neck cancer, and peritonitis carcinomatosa, were used to evaluate the performance of the anti-EpCAM agent with the clinically validated Artemis imaging system. The Pearl Impulse small animal imaging system was used as reference. The specificity of the NIRF signal was confirmed using bioluminescence imaging and green-fluorescent protein. All tumour types could clearly be delineated and resected 72 h after injection of the imaging agent. Using NIRF imaging millimetre sized tumour nodules were detected that were invisible for the naked eye. Fluorescence microscopy demonstrated the distribution and tumour specificity of the anti-EpCAM agent. This study shows the potential of an EpCAM specific NIR-fluorescent agent in combination with a clinically validated intraoperative imaging system to visualize various tumours during surgery

HIDING IN PLAIN SIGHT: RECORD-BREAKING COMPACT STELLAR SYSTEMS IN THE SLOAN DIGITAL SKY SURVEY

International Nuclear Information System (INIS)

Sandoval, Michael A.; Vo, Richard P.; Romanowsky, Aaron J.; Strader, Jay; Choi, Jieun; Conroy, Charlie; Jennings, Zachary G.; Villaume, Alexa; Brodie, Jean P.; Foster, Caroline; Norris, Mark A.; Janz, Joachim; Forbes, Duncan A.

2015-01-01

Motivated by the recent, serendipitous discovery of the densest known galaxy, M60-UCD1, we present two initial findings from a follow-up search, using the Sloan Digital Sky Survey, Subaru/Suprime-Cam, and Hubble Space Telescope imaging, and SOuthern Astrophysical Research (SOAR)/Goodman spectroscopy. The first object discovered, M59-UCD3, has a similar size to M60-UCD1 (half-light radius of r h ∼ 20 pc) but is 40% more luminous (M V ∼ −14.6), making it the new densest-known galaxy. The second, M85-HCC1, has a size like a typical globular cluster (GC; r h ∼ 1.8 pc) but is much more luminous (M V ∼ −12.5). This hypercompact cluster is by far the densest confirmed free-floating stellar system, and is equivalent to the densest known nuclear star clusters. From spectroscopy, we find that both objects are relatively young (∼9 and ∼3 Gyr, respectively), with metal-abundances that resemble those of galaxy centers. Their host galaxies show clear signs of large-scale disturbances, and we conclude that these dense objects are the remnant nuclei of recently accreted galaxies. M59-UCD3 is an ideal target for follow-up with high-resolution imaging and spectroscopy to search for an overweight central supermassive black hole as was discovered in M60-UCD1. These findings also emphasize the potential value of ultra-compact dwarfs and massive GCs as tracers of the assembly histories of galaxies

HIDING IN PLAIN SIGHT: RECORD-BREAKING COMPACT STELLAR SYSTEMS IN THE SLOAN DIGITAL SKY SURVEY

Energy Technology Data Exchange (ETDEWEB)

Sandoval, Michael A.; Vo, Richard P.; Romanowsky, Aaron J. [Department of Physics and Astronomy, San José State University, One Washington Square, San Jose, CA 95192 (United States); Strader, Jay [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Choi, Jieun; Conroy, Charlie [Harvard–Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Jennings, Zachary G.; Villaume, Alexa [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Brodie, Jean P. [University of California Observatories, 1156 High Street, Santa Cruz, CA 95064 (United States); Foster, Caroline [Australian Astronomical Observatory, P.O. Box 915, North Ryde, NSW 1670 (Australia); Norris, Mark A. [Max Planck Institut für Astronomie, Königstuhl 17, D-69117, Heidelberg (Germany); Janz, Joachim; Forbes, Duncan A. [Centre for Astrophysics and Supercomputing, Swinburne University, Hawthorn, VIC 3122 (Australia)

2015-07-20

Motivated by the recent, serendipitous discovery of the densest known galaxy, M60-UCD1, we present two initial findings from a follow-up search, using the Sloan Digital Sky Survey, Subaru/Suprime-Cam, and Hubble Space Telescope imaging, and SOuthern Astrophysical Research (SOAR)/Goodman spectroscopy. The first object discovered, M59-UCD3, has a similar size to M60-UCD1 (half-light radius of r{sub h} ∼ 20 pc) but is 40% more luminous (M{sub V} ∼ −14.6), making it the new densest-known galaxy. The second, M85-HCC1, has a size like a typical globular cluster (GC; r{sub h} ∼ 1.8 pc) but is much more luminous (M{sub V} ∼ −12.5). This hypercompact cluster is by far the densest confirmed free-floating stellar system, and is equivalent to the densest known nuclear star clusters. From spectroscopy, we find that both objects are relatively young (∼9 and ∼3 Gyr, respectively), with metal-abundances that resemble those of galaxy centers. Their host galaxies show clear signs of large-scale disturbances, and we conclude that these dense objects are the remnant nuclei of recently accreted galaxies. M59-UCD3 is an ideal target for follow-up with high-resolution imaging and spectroscopy to search for an overweight central supermassive black hole as was discovered in M60-UCD1. These findings also emphasize the potential value of ultra-compact dwarfs and massive GCs as tracers of the assembly histories of galaxies.

FlowCam: Quantification and Classification of Phytoplankton by Imaging Flow Cytometry.

Science.gov (United States)

Poulton, Nicole J

2016-01-01

The ability to enumerate, classify, and determine biomass of phytoplankton from environmental samples is essential for determining ecosystem function and their role in the aquatic community and microbial food web. Traditional micro-phytoplankton quantification methods using microscopic techniques require preservation and are slow, tedious and very laborious. The availability of more automated imaging microscopy platforms has revolutionized the way particles and cells are detected within their natural environment. The ability to examine cells unaltered and without preservation is key to providing more accurate cell concentration estimates and overall phytoplankton biomass. The FlowCam(®) is an imaging cytometry tool that was originally developed for use in aquatic sciences and provides a more rapid and unbiased method for enumerating and classifying phytoplankton within diverse aquatic environments.

The Role of Public Interaction with the Juno Mission: Documentation, Discussion, Selection and Processing of JunoCam Images of Jovian Cloud Features

Science.gov (United States)

Orton, Glenn; Hansen, Candice; Momary, Thomas; Bolton, Scott

2017-04-01

Among the many "firsts" of the Juno mission is the open enlistment of the public in the operation of its visible camera, JunoCam. Although the scientific thrust of the Juno mission is largely focused on innovative approaches to understanding the structure and composition of Jupiter's interior, JunoCam was added to the payload largely to function in the role of education and public outreach (E/PO). For the first time, the public was able to engage in the discussion and choice of targets for a major NASA mission. The discussion about which features to image is enabled by a continuously updated map of Jupiter's cloud system while Jupiter is far enough from the sun to be observable by non-professional astronomers. Contributors range from very devoted astrophotographers to telescope and video 'hobbyists'. Juno therefore engages the world-wide amateur-astronomy community as a vast network of co-investigators, whose products stimulate conversation and global public awareness of Jupiter and Juno's investigative role. Contributed images also provide a temporal context to inform the Juno atmospheric investigation team of the state and evolution of the atmosphere. The contributed images are used to create s global map on a bi-weekly basis. These bi-weekly maps provide the focus for ongoing discussion about various planetary features over a long time frame. Approximately two weeks before Juno's closest approach to Jupiter on each orbit ("perijove" or PJ), starting in mid-November of 2016 in preparation for PJ3 on December 11, the atmospheric features that have been under discussion and available to JunoCam on that perijove were nominated for voting, and the public at large voted on where to point JunoCam's "elective" features. In addition, JunoCam provides the first close-up images of Jupiter's polar regions from a non-oblique viewpoint for the first time in over 40 years since the passage of Pioneer 11 over Jupiter's north pole. The Juno mission science team also provides

PCI bus content-addressable-memory (CAM) implementation on FPGA for pattern recognition/image retrieval in a distributed environment

Science.gov (United States)

Megherbi, Dalila B.; Yan, Yin; Tanmay, Parikh; Khoury, Jed; Woods, C. L.

2004-11-01

Recently surveillance and Automatic Target Recognition (ATR) applications are increasing as the cost of computing power needed to process the massive amount of information continues to fall. This computing power has been made possible partly by the latest advances in FPGAs and SOPCs. In particular, to design and implement state-of-the-Art electro-optical imaging systems to provide advanced surveillance capabilities, there is a need to integrate several technologies (e.g. telescope, precise optics, cameras, image/compute vision algorithms, which can be geographically distributed or sharing distributed resources) into a programmable system and DSP systems. Additionally, pattern recognition techniques and fast information retrieval, are often important components of intelligent systems. The aim of this work is using embedded FPGA as a fast, configurable and synthesizable search engine in fast image pattern recognition/retrieval in a distributed hardware/software co-design environment. In particular, we propose and show a low cost Content Addressable Memory (CAM)-based distributed embedded FPGA hardware architecture solution with real time recognition capabilities and computing for pattern look-up, pattern recognition, and image retrieval. We show how the distributed CAM-based architecture offers a performance advantage of an order-of-magnitude over RAM-based architecture (Random Access Memory) search for implementing high speed pattern recognition for image retrieval. The methods of designing, implementing, and analyzing the proposed CAM based embedded architecture are described here. Other SOPC solutions/design issues are covered. Finally, experimental results, hardware verification, and performance evaluations using both the Xilinx Virtex-II and the Altera Apex20k are provided to show the potential and power of the proposed method for low cost reconfigurable fast image pattern recognition/retrieval at the hardware/software co-design level.

DISCOVERY OF MASSIVE, MOSTLY STAR FORMATION QUENCHED GALAXIES WITH EXTREMELY LARGE Lyα EQUIVALENT WIDTHS AT z ∼ 3

Energy Technology Data Exchange (ETDEWEB)

Taniguchi, Yoshiaki; Kajisawa, Masaru; Kobayashi, Masakazu A. R.; Nagao, Tohru; Shioya, Yasuhiro [Research Center for Space and Cosmic Evolution, Ehime University, Bunkyo-cho, Matsuyama 790-8577 (Japan); Scoville, Nick Z.; Capak, Peter L. [Department of Astronomy, California Institute of Technology, MS 105-24, Pasadena, CA 91125 (United States); Sanders, David B. [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); Koekemoer, Anton M. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Toft, Sune [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Mariesvej 30, DK-2100 Copenhagen (Denmark); McCracken, Henry J. [Institut d’Astrophysique de Paris, UMR7095 CNRS, Université Pierre et Marie Curie, 98 bis Boulevard Arago, F-75014 Paris (France); Le Fèvre, Olivier; Tasca, Lidia; Ilbert, Olivier [Aix Marseille Université, CNRS, LAM (Laboratoire d’Astrophysique de Marseille), UMR 7326, F-13388 Marseille (France); Sheth, Kartik [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); Renzini, Alvio [Dipartimento di Astronomia, Universita di Padova, vicolo dell’Osservatorio 2, I-35122 Padua (Italy); Lilly, Simon; Carollo, Marcella; Kovač, Katarina [Department of Physics, ETH Zurich, 8093 Zurich (Switzerland); Schinnerer, Eva, E-mail: tani@cosmos.phys.sci.ehime-u.ac.jp [MPI for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); and others

2015-08-10

We report a discovery of six massive galaxies with both extremely large Lyα equivalent widths (EWs) and evolved stellar populations at z ∼ 3. These MAssive Extremely STrong Lyα emitting Objects (MAESTLOs) have been discovered in our large-volume systematic survey for strong Lyα emitters (LAEs) with 12 optical intermediate-band data taken with Subaru/Suprime-Cam in the COSMOS field. Based on the spectral energy distribution fitting analysis for these LAEs, it is found that these MAESTLOs have (1) large rest-frame EWs of EW{sub 0} (Lyα) ∼ 100–300 Å, (2) M{sub ⋆} ∼ 10{sup 10.5}–10{sup 11.1} M{sub ⊙}, and (3) relatively low specific star formation rates of SFR/M{sub ⋆} ∼ 0.03–1 Gyr{sup −1}. Three of the six MAESTLOs have extended Lyα emission with a radius of several kiloparsecs, although they show very compact morphology in the HST/ACS images, which correspond to the rest-frame UV continuum. Since the MAESTLOs do not show any evidence for active galactic nuclei, the observed extended Lyα emission is likely to be caused by a star formation process including the superwind activity. We suggest that this new class of LAEs, MAESTLOs, provides a missing link from star-forming to passively evolving galaxies at the peak era of the cosmic star formation history.

CAD/CAM-assisted breast reconstruction

International Nuclear Information System (INIS)

Melchels, Ferry; Hutmacher, Dietmar Werner; Wiggenhauser, Paul Severin; Schantz, Jan-Thorsten; Warne, David; Barry, Mark; Ong, Fook Rhu; Chong, Woon Shin

2011-01-01

The application of computer-aided design and manufacturing (CAD/CAM) techniques in the clinic is growing slowly but steadily. The ability to build patient-specific models based on medical imaging data offers major potential. In this work we report on the feasibility of employing laser scanning with CAD/CAM techniques to aid in breast reconstruction. A patient was imaged with laser scanning, an economical and facile method for creating an accurate digital representation of the breasts and surrounding tissues. The obtained model was used to fabricate a customized mould that was employed as an intra-operative aid for the surgeon performing autologous tissue reconstruction of the breast removed due to cancer. Furthermore, a solid breast model was derived from the imaged data and digitally processed for the fabrication of customized scaffolds for breast tissue engineering. To this end, a novel generic algorithm for creating porosity within a solid model was developed, using a finite element model as intermediate.

SN 2016jhj at redshift 0.34: extending the Type II supernova Hubble diagram using the standard candle method

Science.gov (United States)

de Jaeger, T.; Galbany, L.; Filippenko, A. V.; González-Gaitán, S.; Yasuda, N.; Maeda, K.; Tanaka, M.; Morokuma, T.; Moriya, T. J.; Tominaga, N.; Nomoto, K.; Komiyama, Y.; Anderson, J. P.; Brink, T. G.; Carlberg, R. G.; Folatelli, G.; Hamuy, M.; Pignata, G.; Zheng, W.

2017-12-01

Although Type Ia supernova cosmology has now reached a mature state, it is important to develop as many independent methods as possible to understand the true nature of dark energy. Recent studies have shown that Type II supernovae (SNe II) offer such a path and could be used as alternative distance indicators. However, the majority of these studies were unable to extend the Hubble diagram above redshift z = 0.3 because of observational limitations. Here, we show that we are now ready to move beyond low redshifts and attempt high-redshift (z ≳ 0.3) SN II cosmology as a result of new-generation deep surveys such as the Subaru/Hyper Suprime-Cam survey. Applying the 'standard candle method' to SN 2016jhj (z = 0.3398 ± 0.0002; discovered by HSC) together with a low-redshift sample, we are able to construct the highest-redshift SN II Hubble diagram to date with an observed dispersion of 0.27 mag (i.e. 12-13 per cent in distance). This work demonstrates the bright future of SN II cosmology in the coming era of large, wide-field surveys like that of the Large Synoptic Survey Telescope.

The path to CAM6: coupled simulations with CAM5.4 and CAM5.5

Science.gov (United States)

Bogenschutz, Peter A.; Gettelman, Andrew; Hannay, Cecile; Larson, Vincent E.; Neale, Richard B.; Craig, Cheryl; Chen, Chih-Chieh

2018-01-01

This paper documents coupled simulations of two developmental versions of the Community Atmosphere Model (CAM) towards CAM6. The configuration called CAM5.4 introduces new microphysics, aerosol, and ice nucleation changes, among others to CAM. The CAM5.5 configuration represents a more radical departure, as it uses an assumed probability density function (PDF)-based unified cloud parameterization to replace the turbulence, shallow convection, and warm cloud macrophysics in CAM. This assumed PDF method has been widely used in the last decade in atmosphere-only climate simulations but has never been documented in coupled mode. Here, we compare the simulated coupled climates of CAM5.4 and CAM5.5 and compare them to the control coupled simulation produced by CAM5.3. We find that CAM5.5 has lower cloud forcing biases when compared to the control simulations. Improvements are also seen in the simulated amplitude of the Niño-3.4 index, an improved representation of the diurnal cycle of precipitation, subtropical surface wind stresses, and double Intertropical Convergence Zone biases. Degradations are seen in Amazon precipitation as well as slightly colder sea surface temperatures and thinner Arctic sea ice. Simulation of the 20th century results in a credible simulation that ends slightly colder than the control coupled simulation. The authors find this is due to aerosol indirect effects that are slightly stronger in the new version of the model and propose a solution to ameliorate this. Overall, in these early coupled simulations, CAM5.5 produces a credible climate that is appropriate for science applications and is ready for integration into the National Center for Atmospheric Research's (NCAR's) next-generation climate model.

QUANTIFICATION OF ANGIOGENESIS IN THE CHICKEN CHORIOALLANTOIC MEMBRANE (CAM

Directory of Open Access Journals (Sweden)

Silvia Blacher

2011-05-01

Full Text Available The chick chorioallantoic membrane (CAM provides a suitable in vivo model to study angiogenesis and evaluate several pro- and anti-angiogenic factors and compounds. In the present work, new developments in image analysis are used to quantify CAM angiogenic response from optical microscopic observations, covering all vascular components, from the large supplying and feeding vessels down to the capillary plexus. To validate our methodology angiogenesis is quantified during two phases of CAM development (day 7 and 13 and after treatment with an antiangiogenic modulator of the angiogenesis. Our morphometric analysis emphasizes that an accurate quantification of the CAM vasculature needs to be performed at various scales.

Camera-augmented mobile C-arm (CamC): A feasibility study of augmented reality imaging in the operating room.

Science.gov (United States)

von der Heide, Anna Maria; Fallavollita, Pascal; Wang, Lejing; Sandner, Philipp; Navab, Nassir; Weidert, Simon; Euler, Ekkehard

2018-04-01

In orthopaedic trauma surgery, image-guided procedures are mostly based on fluoroscopy. The reduction of radiation exposure is an important goal. The purpose of this work was to investigate the impact of a camera-augmented mobile C-arm (CamC) on radiation exposure and the surgical workflow during a first clinical trial. Applying a workflow-oriented approach, 10 general workflow steps were defined to compare the CamC to traditional C-arms. The surgeries included were arbitrarily identified and assigned to the study. The evaluation criteria were radiation exposure and operation time for each workflow step and the entire surgery. The evaluation protocol was designed and conducted in a single-centre study. The radiation exposure was remarkably reduced by 18 X-ray shots 46% using the CamC while keeping similar surgery times. The intuitiveness of the system, its easy integration into the surgical workflow, and its great potential to reduce radiation have been demonstrated. Copyright © 2017 John Wiley & Sons, Ltd.

SenseCam: A new tool for memory rehabilitation?

Science.gov (United States)

Dubourg, L; Silva, A R; Fitamen, C; Moulin, C J A; Souchay, C

2016-12-01

The emergence of life-logging technologies has led neuropsychologist to focus on understanding how this new technology could help patients with memory disorders. Despite the growing number of studies using life-logging technologies, a theoretical framework supporting its effectiveness is lacking. This review focuses on the use of life-logging in the context of memory rehabilitation, particularly the use of SenseCam, a wearable camera allowing passive image capture. In our opinion, reviewing SenseCam images can be effective for memory rehabilitation only if it provides more than an assessment of prior occurrence in ways that reinstates previous thoughts, feelings and sensory information, thus stimulating recollection. Considering the fact that, in memory impairment, self-initiated processes are impaired, we propose that the environmental support hypothesis can explain the value of SenseCam for memory retrieval. Twenty-five research studies were selected for this review and despite the general acceptance of the value of SenseCam as a memory technique, only a small number of studies focused on recollection. We discuss the usability of this tool to improve episodic memory and in particular, recollection. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

J0454-0309: evidence of a strong lensing fossil group falling into a poor galaxy cluster

Science.gov (United States)

Schirmer, M.; Suyu, S.; Schrabback, T.; Hildebrandt, H.; Erben, T.; Halkola, A.

2010-05-01

Aims: We have discovered a strong lensing fossil group (J0454) projected near the well-studied cluster MS0451-0305. Using the large amount of available archival data, we compare J0454 to normal groups and clusters. A highly asymmetric image configuration of the strong lens enables us to study the substructure of the system. Methods: We used multicolour Subaru/Suprime-Cam and CFHT/Megaprime imaging, together with Keck spectroscopy to identify member galaxies. A VLT/FORS2 spectrum was taken to determine the redshifts of the brightest elliptical and the lensed arc. Using HST/ACS images, we determined the group's weak lensing signal and modelled the strong lens system. This is the first time that a fossil group is analysed with lensing methods. The X-ray luminosity and temperature were derived from XMM-Newton data. Results: J0454 is located at z = 0.26, with a gap of 2.5 mag between the brightest and second brightest galaxies within half the virial radius. Outside a radius of 1.5 Mpc, we find two filaments extending over 4 Mpc, and within we identify 31 members spectroscopically and 33 via the red sequence with i systems, a sparse cluster and an infalling fossil group, where the latter seeds the brightest cluster galaxy. An alternative to the sparse cluster could be a filament projected along the line of sight mimicking a cluster, with galaxies streaming towards the fossil group. This work is based on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan; based on observations obtained with MegaPrime/MegaCam, a joint project of CFHT and CEA/DAPNIA, at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii; based on observations made with ESO Telescopes at the La Silla and Paranal Observatories, Chile (ESO DDT

Modified FlowCAM procedure for quantifying size distribution of zooplankton with sample recycling capacity.

Directory of Open Access Journals (Sweden)

Esther Wong

Full Text Available We have developed a modified FlowCAM procedure for efficiently quantifying the size distribution of zooplankton. The modified method offers the following new features: 1 prevents animals from settling and clogging with constant bubbling in the sample container; 2 prevents damage to sample animals and facilitates recycling by replacing the built-in peristaltic pump with an external syringe pump, in order to generate negative pressure, creates a steady flow by drawing air from the receiving conical flask (i.e. vacuum pump, and transfers plankton from the sample container toward the main flowcell of the imaging system and finally into the receiving flask; 3 aligns samples in advance of imaging and prevents clogging with an additional flowcell placed ahead of the main flowcell. These modifications were designed to overcome the difficulties applying the standard FlowCAM procedure to studies where the number of individuals per sample is small, and since the FlowCAM can only image a subset of a sample. Our effective recycling procedure allows users to pass the same sample through the FlowCAM many times (i.e. bootstrapping the sample in order to generate a good size distribution. Although more advanced FlowCAM models are equipped with syringe pump and Field of View (FOV flowcells which can image all particles passing through the flow field; we note that these advanced setups are very expensive, offer limited syringe and flowcell sizes, and do not guarantee recycling. In contrast, our modifications are inexpensive and flexible. Finally, we compared the biovolumes estimated by automated FlowCAM image analysis versus conventional manual measurements, and found that the size of an individual zooplankter can be estimated by the FlowCAM image system after ground truthing.

FluidCam 1&2 - UAV-based Fluid Lensing Instruments for High-Resolution 3D Subaqueous Imaging and Automated Remote Biosphere Assessment of Reef Ecosystems

Science.gov (United States)

Chirayath, V.; Instrella, R.

2016-02-01

We present NASA ESTO FluidCam 1 & 2, Visible and NIR Fluid-Lensing-enabled imaging payloads for Unmanned Aerial Vehicles (UAVs). Developed as part of a focused 2014 earth science technology grant, FluidCam 1&2 are Fluid-Lensing-based computational optical imagers designed for automated 3D mapping and remote sensing of underwater coastal targets from airborne platforms. Fluid Lensing has been used to map underwater reefs in 3D in American Samoa and Hamelin Pool, Australia from UAV platforms at sub-cm scale, which has proven a valuable tool in modern marine research for marine biosphere assessment and conservation. We share FluidCam 1&2 instrument validation and testing results as well as preliminary processed data from field campaigns. Petabyte-scale aerial survey efforts using Fluid Lensing to image at-risk reefs demonstrate broad applicability to large-scale automated species identification, morphology studies and reef ecosystem characterization for shallow marine environments and terrestrial biospheres, of crucial importance to improving bathymetry data for physical oceanographic models and understanding climate change's impact on coastal zones, global oxygen production, carbon sequestration.

Angle assessment by EyeCam, goniophotography, and gonioscopy.

Science.gov (United States)

Baskaran, Mani; Perera, Shamira A; Nongpiur, Monisha E; Tun, Tin A; Park, Judy; Kumar, Rajesh S; Friedman, David S; Aung, Tin

2012-09-01

To compare EyeCam (Clarity Medical Systems, Pleasanton, CA) and goniophotography in detecting angle closure, using gonioscopy as the reference standard. In this hospital-based, prospective, cross-sectional study, participants underwent gonioscopy by a single observer, and EyeCam imaging and goniophotography by different operators. The anterior chamber angle in a quadrant was classified as closed if the posterior trabecular meshwork could not be seen. A masked observer categorized the eyes as per the number of closed quadrants, and an eye was classified as having angle closure if there were 2 or more quadrants of closure. Agreement between the methods was analyzed by κ statistic and comparison of area under receiver operating characteristic curves (AUC). Eighty-five participants (85 eyes) were included, the majority of whom were Chinese. Angle closure was detected in 38 eyes (45%) with gonioscopy, 40 eyes (47%) using EyeCam, and 40 eyes (47%) with goniophotography (P=0.69 in both comparisons, McNemar test). The agreement for angle closure diagnosis (by eye) between gonioscopy and the 2 imaging modalities was high (κ=0.86; 95% Confidence Interval (CI), 0.75-0.97), whereas the agreement between EyeCam and goniophotography was not as good (κ=0.72; 95% CI, 0.57-0.87); largely due to lack of agreement in the nasal and temporal quadrants (κ=0.55 to 0.67). The AUC for detecting eyes with gonioscopic angle closure was similar for goniophotography and EyeCam (AUC 0.93, sensitivity=94.7%, specificity=91.5%; P>0.95). EyeCam and goniophotography have similarly high sensitivity and specificity for the detection of gonioscopic angle closure.

SenseCam improves memory for recent events and quality of life in a patient with memory retrieval difficulties.

Science.gov (United States)

Browne, Georgina; Berry, Emma; Kapur, Narinder; Hodges, Steve; Smyth, Gavin; Watson, Peter; Wood, Ken

2011-10-01

A wearable camera that takes pictures automatically, SenseCam, was used to generate images for rehearsal, promoting consolidation and retrieval of memories for significant events in a patient with memory retrieval deficits. SenseCam images of recent events were systematically reviewed over a 2-week period. Memory for these events was assessed throughout and longer-term recall was tested up to 6 months later. A written diary control condition followed the same procedure. The SenseCam review procedure resulted in significantly more details of an event being recalled, with twice as many details recalled at 6 months follow up compared to the written diary method. Self-report measures suggested autobiographical recollection was triggered by the SenseCam condition but not by reviewing the written diary. Emotional and social wellbeing questionnaires indicated improved confidence and decreased anxiety as a result of memory rehearsal using SenseCam images. We propose that SenseCam images provide a powerful boost to autobiographical recall, with secondary benefits for quality of life.

Environment Study of AGNs at z = 0.3 to 3.0 Using the Japanese Virtual Observatory

Science.gov (United States)

Shirasaki, Y.; Ohishi, M.; Mizumoto, Y.; Takata, T.; Tanaka, M.; Yasuda, N.

2010-12-01

We present a science use case of Virtual Observatory, which was achieved to examine an environment of AGN up to redshift of 3.0. We used the Japanese Virtual Observatory (JVO) to obtain Subaru Suprime-Cam images around known AGNs. According to the hierarchical galaxy formation model, AGNs are expected to be found in an environment of higher galaxy density than that of typical galaxies. The current observations, however, indicate that AGNs do not reside in a particularly high density environment. We investigated ˜1000 AGNs, which is about ten times larger samples than the other studies covering the redshifts larger than 0.6. We successfully found significant excess of galaxies around AGNs at redshifts of 0.3 to 1.8. If this work was done in a classical manner, that is, raw data were retrieved from the archive through a form-based web interface in an interactive way, and the data were reduced on a low performance computer, it might take several years to finish it. Since the Virtual Observatory system is accessible through a standard interface, it is easy to query and retrieve data in an automatic way. We constructed a pipeline for retrieving the data and calculating the galaxy number density around a given coordinate. This procedure was executed in parallel on ˜10 quad core PCs, and it took only one day for obtaining the final result. Our result implies that the Virtual Observatory can be a powerful tool to do an astronomical research based on large amount of data.

Cryogenic Cam Butterfly Valve

Science.gov (United States)

McCormack, Kenneth J. (Inventor)

2016-01-01

A cryogenic cam butterfly valve has a body that includes an axially extending fluid conduit formed there through. A disc lug is connected to a back side of a valve disc and has a circular bore that receives and is larger than a cam of a cam shaft. The valve disc is rotatable for a quarter turn within the body about a lug axis that is offset from the shaft axis. Actuating the cam shaft in the closing rotational direction first causes the camming side of the cam of the cam shaft to rotate the disc lug and the valve disc a quarter turn from the open position to the closed position. Further actuating causes the camming side of the cam shaft to translate the valve disc into sealed contact with the valve seat. Opening rotational direction of the cam shaft reverses these motions.

Memory for staged events: Supporting older and younger adults' memory with SenseCam.

Science.gov (United States)

Mair, Ali; Poirier, Marie; Conway, Martin A

2018-03-01

Two experiments measured the effect of retrieval support provided by a wearable camera, SenseCam, on older and younger adults' memory for a recently experienced complex staged event. In each experiment, participants completed a series of tasks in groups, and the events were recalled 2 weeks later, after viewing SenseCam images (experimental condition) or thinking about the event (control condition). When IQ and education were matched, young adults recalled more event details than older adults, demonstrating an age-related deficit for novel autobiographical material. Reviewing SenseCam images increased the number of details recalled by older and younger adults, and the effect was similar for both groups. These results suggest that memory can be supported by the use of SenseCam, but the age-related deficit is not eliminated.

Comparison of EyeCam and anterior segment optical coherence tomography in detecting angle closure.

Science.gov (United States)

Baskaran, Mani; Aung, Tin; Friedman, David S; Tun, Tin A; Perera, Shamira A

2012-12-01

To compare the diagnostic performance of EyeCam (Clarity Medical Systems, Pleasanton, CA, USA) and anterior segment optical coherence tomography (ASOCT, Visante; Carl Zeiss Meditec, Dublin, CA, USA) in detecting angle closure, using gonioscopy as the reference standard. Ninety-eight phakic patients, recruited from a glaucoma clinic, underwent gonioscopy by a single examiner, and EyeCam and ASOCT imaging by another examiner. Another observer, masked to gonioscopy findings, graded EyeCam and ASOCT images. For both gonioscopy and EyeCam, a closed angle in a particular quadrant was defined if the posterior trabecular meshwork was not visible. For ASOCT, angle closure was defined by any contact between the iris and angle anterior to the scleral spur. An eye was diagnosed as having angle closure if ≥2 quadrants were closed. Agreement and area under the receiver operating characteristic curves (AUC) were evaluated. The majority of subjects were Chinese (69/98, 70.4%) with a mean age of 60.6 years. Angle closure was diagnosed in 39/98 (39.8%) eyes with gonioscopy, 40/98 (40.8%) with EyeCam and 56/97 (57.7%) with ASOCT. The agreement (kappa statistic) for angle closure diagnosis for gonioscopy versus EyeCam was 0.89; gonioscopy versus ASOCT and EyeCam versus ASOCT were both 0.56. The AUC for detecting eyes with gonioscopic angle closure with EyeCam was 0.978 (95% CI: 0.93-1.0) and 0.847 (95% CI: 0.76-0.92, p < 0.01) for ASOCT. The diagnostic performance of EyeCam was better than ASOCT in detecting angle closure when gonioscopic grading was used as the reference standard. The agreement between the two imaging modalities was moderate. © 2012 The Authors. Acta Ophthalmologica © 2012 Acta Ophthalmologica Scandinavica Foundation.

Dual-Color Fluorescence Imaging of EpCAM and EGFR in Breast Cancer Cells with a Bull's Eye-Type Plasmonic Chip.

Science.gov (United States)

Izumi, Shota; Yamamura, Shohei; Hayashi, Naoko; Toma, Mana; Tawa, Keiko

2017-12-19

Surface plasmon field-enhanced fluorescence microscopic observation of a live breast cancer cell was performed with a plasmonic chip. Two cell lines, MDA-MB-231 and Michigan Cancer Foundation-7 (MCF-7), were selected as breast cancer cells, with two kinds of membrane protein, epithelial cell adhesion molecule (EpCAM) and epidermal growth factor receptor (EGFR), observed in both cells. The membrane proteins are surface markers used to differentiate and classify breast cancer cells. EGFR and EpCAM were detected with Alexa Fluor ® 488-labeled anti-EGFR antibody (488-EGFR) and allophycocyanin (APC)-labeled anti-EpCAM antibody (APC-EpCAM), respectively. In MDA-MB231 cells, three-fold plus or minus one and seven-fold plus or minus two brighter fluorescence of 488-EGFR were observed on the 480-nm pitch and the 400-nm pitch compared with that on a glass slide. Results show the 400-nm pitch is useful. Dual-color fluorescence of 488-EGFR and APC-EpCAM in MDA-MB231 was clearly observed with seven-fold plus or minus two and nine-fold plus or minus three, respectively, on the 400-nm pitch pattern of a plasmonic chip. Therefore, the 400-nm pitch contributed to the dual-color fluorescence enhancement for these wavelengths. An optimal grating pitch of a plasmonic chip improved a fluorescence image of membrane proteins with the help of the surface plasmon-enhanced field.

UNUSUAL LONG AND LUMINOUS OPTICAL TRANSIENT IN THE SUBARU DEEP FIELD

International Nuclear Information System (INIS)

Urata, Yuji; Tsai, Patrick P.; Huang, Kuiyun; Morokuma, Tomoki; Motohara, Kentaro; Yasuda, Naoki; Tanaka, Masaomi; Hayashi, Masao; Kashikawa, Nobunari; Ly, Chun; Malkan, Matthew A.

2012-01-01

We present observations of SDF-05M05, an unusual optical transient discovered in the Subaru Deep Field (SDF). The duration of the transient is > ∼ 800 days in the observer frame, and the maximum brightness during observation reached approximately 23 mag in the i' and z' bands. The faint host galaxy is clearly identified in all five optical bands of the deep SDF images. The photometric redshift of the host yields z ∼ 0.6 and the corresponding absolute magnitude at maximum is ∼ – 20. This implies that this event shone with an absolute magnitude brighter than –19 mag for approximately 300 days in the rest frame, which is significantly longer than a typical supernova and ultraluminous supernova. The total radiated energy during our observation was 1 × 10 51 erg. The light curves and color evolution are marginally consistent with some luminous IIn supernovae. We suggest that the transient may be a unique and peculiar supernova at intermediate redshift.

UNUSUAL LONG AND LUMINOUS OPTICAL TRANSIENT IN THE SUBARU DEEP FIELD

Energy Technology Data Exchange (ETDEWEB)

Urata, Yuji; Tsai, Patrick P. [Institute of Astronomy, National Central University, Chung-Li 32054, Taiwan (China); Huang, Kuiyun [Academia Sinica Institute of Astronomy and Astrophysics, Taipei 106, Taiwan (China); Morokuma, Tomoki; Motohara, Kentaro [Institute of Astronomy, Graduate School of Science, University of Tokyo, Mitaka, Tokyo 181-0015 (Japan); Yasuda, Naoki [Institute for the Physics and Mathematics of the Universe, University of Tokyo, Kashiwa 277-8568 (Japan); Tanaka, Masaomi; Hayashi, Masao; Kashikawa, Nobunari [Optical and Infrared Astronomy Division, National Astronomical Observatory, Mitaka, Tokyo 181-8588 (Japan); Ly, Chun [Space Telescope Science Institute, Baltimore, MD (United States); Malkan, Matthew A., E-mail: urata@astro.ncu.edu.tw [Department of Physics and Astronomy, UCLA, Box 951547, Los Angeles, CA (United States)

2012-11-20

We present observations of SDF-05M05, an unusual optical transient discovered in the Subaru Deep Field (SDF). The duration of the transient is > {approx} 800 days in the observer frame, and the maximum brightness during observation reached approximately 23 mag in the i' and z' bands. The faint host galaxy is clearly identified in all five optical bands of the deep SDF images. The photometric redshift of the host yields z {approx} 0.6 and the corresponding absolute magnitude at maximum is {approx} - 20. This implies that this event shone with an absolute magnitude brighter than -19 mag for approximately 300 days in the rest frame, which is significantly longer than a typical supernova and ultraluminous supernova. The total radiated energy during our observation was 1 Multiplication-Sign 10{sup 51} erg. The light curves and color evolution are marginally consistent with some luminous IIn supernovae. We suggest that the transient may be a unique and peculiar supernova at intermediate redshift.

Quantifying particulate matter deposition in Niwot Ridge, Colorado: Collection of dry deposition using marble inserts and particle imaging using the FlowCAM

Science.gov (United States)

Goss, Natasha R.; Mladenov, Natalie; Seibold, Christine M.; Chowanski, Kurt; Seitz, Leslie; Wellemeyer, T. Barret; Williams, Mark W.

2013-12-01

Atmospheric wet and dry deposition are important sources of carbon for remote alpine lakes and soils. The carbon inputs from dry deposition in alpine National Atmospheric Deposition Program (NADP) collectors, including aeolian dust and biological material, are not well constrained due to difficulties in retaining particulate matter in the collectors. Here, we developed and tested a marble insert for dry deposition collection at the Niwot Ridge Long Term Ecological Research Station (NWT LTER) Soddie site (3345 m) between 24 May and 8 November 2011. We conducted laboratory tests of the insert's effect on particulate matter (PM) mass and non-purgeable organic carbon (DOC) and found that the insert did not significantly change either measurement. Thus, the insert may enable dry deposition collection of PM and DOC at NADP sites. We then developed a method for enumerating the collected wet and dry deposition with the Flow Cytometer and Microscope (FlowCAM), a dynamic-image particle analysis tool. The FlowCAM has the potential to establish morphology, which affects particle settling and retention, through particle diameter and aspect ratio. Particle images were used to track the abundance of pollen grains over time. Qualitative image examination revealed that most particles were biological in nature, such as intact algal cells and pollen. Dry deposition loading to the Soddie site as determined by FlowCAM measurements was highly variable, ranging from 100 to >230 g ha-1 d-1 in June-August 2011 and peaking in late June. No significant difference in diameter or aspect ratio was found between wet and dry deposition, suggesting fundamental similarities between those deposition types. Although FlowCAM statistics and identification of particle types proved insightful, our total-particle enumeration method had a high variance and underestimated the total number of particles when compared to imaging of relatively large volumes (60-125 mL) from a single sample. We recommend use of

THE SLUGGS SURVEY: NGC 3115, A CRITICAL TEST CASE FOR METALLICITY BIMODALITY IN GLOBULAR CLUSTER SYSTEMS

International Nuclear Information System (INIS)

Brodie, Jean P.; Conroy, Charlie; Arnold, Jacob A.; Romanowsky, Aaron J.; Usher, Christopher; Forbes, Duncan A.; Strader, Jay

2012-01-01

Due to its proximity (9 Mpc) and the strongly bimodal color distribution of its spectroscopically well-sampled globular cluster (GC) system, the early-type galaxy NGC 3115 provides one of the best available tests of whether the color bimodality widely observed in GC systems generally reflects a true metallicity bimodality. Color bimodality has alternatively been attributed to a strongly nonlinear color-metallicity relation reflecting the influence of hot horizontal-branch stars. Here, we couple Subaru Suprime-Cam gi photometry with Keck/DEIMOS spectroscopy to accurately measure GC colors and a CaT index that measures the Ca II triplet. We find the NGC 3115 GC system to be unambiguously bimodal in both color and the CaT index. Using simple stellar population models, we show that the CaT index is essentially unaffected by variations in horizontal-branch morphology over the range of metallicities relevant to GC systems (and is thus a robust indicator of metallicity) and confirm bimodality in the metallicity distribution. We assess the existing evidence for and against multiple metallicity subpopulations in early- and late-type galaxies and conclude that metallicity bi/multimodality is common. We briefly discuss how this fundamental characteristic links directly to the star formation and assembly histories of galaxies.

THE SLUGGS SURVEY: NGC 3115, A CRITICAL TEST CASE FOR METALLICITY BIMODALITY IN GLOBULAR CLUSTER SYSTEMS

Energy Technology Data Exchange (ETDEWEB)

Brodie, Jean P.; Conroy, Charlie; Arnold, Jacob A.; Romanowsky, Aaron J. [University of California Observatories and Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Usher, Christopher; Forbes, Duncan A. [Centre for Astrophysics and Supercomputing, Swinburne University, Hawthorn, VIC 3122 (Australia); Strader, Jay, E-mail: brodie@ucolick.org [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States)

2012-11-10

Due to its proximity (9 Mpc) and the strongly bimodal color distribution of its spectroscopically well-sampled globular cluster (GC) system, the early-type galaxy NGC 3115 provides one of the best available tests of whether the color bimodality widely observed in GC systems generally reflects a true metallicity bimodality. Color bimodality has alternatively been attributed to a strongly nonlinear color-metallicity relation reflecting the influence of hot horizontal-branch stars. Here, we couple Subaru Suprime-Cam gi photometry with Keck/DEIMOS spectroscopy to accurately measure GC colors and a CaT index that measures the Ca II triplet. We find the NGC 3115 GC system to be unambiguously bimodal in both color and the CaT index. Using simple stellar population models, we show that the CaT index is essentially unaffected by variations in horizontal-branch morphology over the range of metallicities relevant to GC systems (and is thus a robust indicator of metallicity) and confirm bimodality in the metallicity distribution. We assess the existing evidence for and against multiple metallicity subpopulations in early- and late-type galaxies and conclude that metallicity bi/multimodality is common. We briefly discuss how this fundamental characteristic links directly to the star formation and assembly histories of galaxies.

Subaru XV: una estrategia de comunicación y mercadeo para la generación Y

Directory of Open Access Journals (Sweden)

Guillermo Armelini

2013-03-01

Full Text Available En el año 2009 las ventas en la industria automotriz disminuyeron. El año 2010 había comenzado mucho mejor. En este contexto, Subaru Chile, un actor del mercado con una cuota relativamente pequeña (anexo 1, decidió introducir un nuevo modelo: Subaru XV, un crossover que se presentaba como la gran apuesta para el creciente mercado de los SUV (anexos 6 y 7 El desafío de lanzar este modelo presentaba varias aristas. En primer lugar, el mercado de este tipo de vehículos ya estaba muy desarrollado por actores importantes como Toyota, Nissan y Renault (anexo 7. En segundo lugar, Subaru tenía que dirigir su acción comercial a un nuevo segmento de mercado (jóvenes entre 20 y 35 años que desconocía y, consecuentemente, debía estudiar sus hábitos y necesidades, y definir el sistema de comunicación más acorde para este target.

Calcium Sulfate Characterized by ChemCam/Curiosity at Gale Crater, Mars

Science.gov (United States)

Nachon, M.; Clegg, S. N.; Mangold, N.; Schroeder, S.; Kah, L. C.; Dromart, G.; Ollila, A.; Johnson, J. R.; Oehler, D. Z.; Bridges, J. C.;

The Subaru Fauresmith 200km Challenge: Looking a Gift-Horse in ...

African Journals Online (AJOL)

This article describes an equestrian sport known as 'endurance riding.' It focuses on the Subaru Fauresmith 200km Challenge, which is held every year in the small southern Free State town of Fauresmith. Given the steadily growing profi le of the event, both locally and internationally, it is argued that the time is ripe for ...

Monitoring and Precision Spraying for Orchid Plantation with Wireless WebCAMs

Directory of Open Access Journals (Sweden)

Grianggai Samseemoung

2017-10-01

Full Text Available Through processing images taken from wireless WebCAMs on the low altitude remote sensing (LARS platform, this research monitored crop growth, pest, and disease information in a dendrobium orchid’s plantation. Vegetetative indices were derived for distinguishing different stages of crop growth, and the infestation density of pests and diseases. Image data was processed through an algorithm created in MATLAB® (The MathWorks, Inc., Natick, USA. Corresponding to the orchid’s growth stage and its infestation density, varying levels of fertilizer and chemical injections were administered. The acquired LARS images from wireless WebCAMs were positioned using geo-referencing, and eventually processed to estimate vegetative-indices (Red = 650 nm and NIR = 800 nm band center. Good correlations and a clear cluster range were obtained in characteristic plots of the normalized difference vegetation index (NDVI and the green normalized difference vegetation index (GNDVI against chlorophyll content. The coefficient of determination, the chlorophyll content values (μmol m−2 showed significant differences among clusters for healthy orchids (R2 = 0.985–0.992, and for infested orchids (R2 = 0.984–0.998. The WebCAM application, while being inexpensive, provided acceptable inputs for image processing. The LARS platform gave its best performance at an altitude of 1.2 m above canopy. The image processing software based on LARS images provided satisfactory results as compared with manual measurements.

Special Section: Complementary and Alternative Medicine (CAM): Low Back Pain and CAM

Science.gov (United States)

... Home Current Issue Past Issues Special Section CAM Low Back Pain and CAM Past Issues / Winter 2009 Table of ... benefit from CAM treatment for conditions such as low back pain. Photo courtesy of Glenn Scimonelli "Oh, my aching ...

Facultative crassulacean acid metabolism (CAM) plants: powerful tools for unravelling the functional elements of CAM photosynthesis.

Science.gov (United States)

Winter, Klaus; Holtum, Joseph A M

2014-07-01

Facultative crassulacean acid metabolism (CAM) describes the optional use of CAM photosynthesis, typically under conditions of drought stress, in plants that otherwise employ C3 or C4 photosynthesis. In its cleanest form, the upregulation of CAM is fully reversible upon removal of stress. Reversibility distinguishes facultative CAM from ontogenetically programmed unidirectional C3-to-CAM shifts inherent in constitutive CAM plants. Using mainly measurements of 24h CO2 exchange, defining features of facultative CAM are highlighted in five terrestrial species, Clusia pratensis, Calandrinia polyandra, Mesembryanthemum crystallinum, Portulaca oleracea and Talinum triangulare. For these, we provide detailed chronologies of the shifts between photosynthetic modes and comment on their usefulness as experimental systems. Photosynthetic flexibility is also reviewed in an aquatic CAM plant, Isoetes howellii. Through comparisons of C3 and CAM states in facultative CAM species, many fundamental biochemical principles of the CAM pathway have been uncovered. Facultative CAM species will be of even greater relevance now that new sequencing technologies facilitate the mapping of genomes and tracking of the expression patterns of multiple genes. These technologies and facultative CAM systems, when joined, are expected to contribute in a major way towards our goal of understanding the essence of CAM. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

The SAGES Legacy Unifying Globulars and Galaxies survey (SLUGGS): sample definition, methods, and initial results

Energy Technology Data Exchange (ETDEWEB)

Brodie, Jean P.; Romanowsky, Aaron J.; Jennings, Zachary G.; Pota, Vincenzo; Kader, Justin; Roediger, Joel C.; Villaume, Alexa; Arnold, Jacob A.; Woodley, Kristin A. [University of California Observatories, 1156 High Street, Santa Cruz, CA 95064 (United States); Strader, Jay [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Forbes, Duncan A.; Pastorello, Nicola; Usher, Christopher; Blom, Christina; Kartha, Sreeja S. [Centre for Astrophysics and Supercomputing, Swinburne University, Hawthorn, VIC 3122 (Australia); Foster, Caroline; Spitler, Lee R., E-mail: jbrodie@ucsc.edu [Australian Astronomical Observatory, P.O. Box 915, North Ryde, NSW 1670 (Australia)

2014-11-20

We introduce and provide the scientific motivation for a wide-field photometric and spectroscopic chemodynamical survey of nearby early-type galaxies (ETGs) and their globular cluster (GC) systems. The SAGES Legacy Unifying Globulars and GalaxieS (SLUGGS) survey is being carried out primarily with Subaru/Suprime-Cam and Keck/DEIMOS. The former provides deep gri imaging over a 900 arcmin{sup 2} field-of-view to characterize GC and host galaxy colors and spatial distributions, and to identify spectroscopic targets. The NIR Ca II triplet provides GC line-of-sight velocities and metallicities out to typically ∼8 R {sub e}, and to ∼15 R {sub e} in some cases. New techniques to extract integrated stellar kinematics and metallicities to large radii (∼2-3 R {sub e}) are used in concert with GC data to create two-dimensional (2D) velocity and metallicity maps for comparison with simulations of galaxy formation. The advantages of SLUGGS compared with other, complementary, 2D-chemodynamical surveys are its superior velocity resolution, radial extent, and multiple halo tracers. We describe the sample of 25 nearby ETGs, the selection criteria for galaxies and GCs, the observing strategies, the data reduction techniques, and modeling methods. The survey observations are nearly complete and more than 30 papers have so far been published using SLUGGS data. Here we summarize some initial results, including signatures of two-phase galaxy assembly, evidence for GC metallicity bimodality, and a novel framework for the formation of extended star clusters and ultracompact dwarfs. An integrated overview of current chemodynamical constraints on GC systems points to separate, in situ formation modes at high redshifts for metal-poor and metal-rich GCs.

Wavelength-Dependent PSFs and their Impact on Weak Lensing Measurements

Science.gov (United States)

Carlsten, S. G.; Strauss, Michael A.; Lupton, Robert H.; Meyers, Joshua E.; Miyazaki, Satoshi

2018-06-01

We measure and model the wavelength dependence of the point spread function (PSF) in the Hyper Suprime-Cam Subaru Strategic Program survey. We find that PSF chromaticity is present in that redder stars appear smaller than bluer stars in the g, r, and i-bands at the 1-2 per cent level and in the z and y-bands at the 0.1-0.2 per cent level. From the color dependence of the PSF, we fit a model between the monochromatic PSF size based on weighted second moments, R, and wavelength of the form R(λ)∝λ-b. We find values of b between 0.2 and 0.5, depending on the epoch and filter. This is consistent with the expectations of a turbulent atmosphere with an outer scale length of ˜10 - 100 m, indicating that the atmosphere is dominating the chromaticity. In the best seeing data, we find that the optical system and detector also contribute some wavelength dependence. Meyers & Burchat (2015b) showed that b must be measured to an accuracy of ˜0.02 not to dominate the systematic error budget of the Large Synoptic Survey Telescope (LSST) weak lensing (WL) survey. Using simple image simulations, we find that b can be inferred with this accuracy in the r and i-bands for all positions in the LSST focal plane, assuming a stellar density of 1 star arcmin-2 and that the optical component of the PSF can be accurately modeled. Therefore, it is possible to correct for most, if not all, of the bias that the wavelength-dependent PSF will introduce into an LSST-like WL survey.

METAMORPHOSIS OF SN 2014C: DELAYED INTERACTION BETWEEN A HYDROGEN POOR CORE-COLLAPSE SUPERNOVA AND A NEARBY CIRCUMSTELLAR SHELL

International Nuclear Information System (INIS)

Milisavljevic, D.; Margutti, R.; Kamble, A.; Patnaude, D. J.; Raymond, J. C.; Challis, P.; Drout, M. R.; Grindlay, J. E.; Kirshner, R. P.; Lunnan, R.; Miller, G. F.; Parrent, J. T.; Sanders, N. E.; Eldridge, J. J.; Fong, W.; Bietenholz, M.; Chornock, R.; Fransson, C.; Fesen, R. A.; Mackey, J.

2015-01-01

We present optical observations of supernova SN 2014C, which underwent an unprecedented slow metamorphosis from H-poor type Ib to H-rich type IIn over the course of one year. The observed spectroscopic evolution is consistent with the supernova having exploded in a cavity before encountering a massive shell of the progenitor star’s stripped hydrogen envelope. Possible origins for the circumstellar shell include a brief Wolf–Rayet fast wind phase that overtook a slower red supergiant wind, eruptive ejection, or confinement of circumstellar material by external influences of neighboring stars. An extended high velocity Hα absorption feature seen in near-maximum light spectra implies that the progenitor star was not completely stripped of hydrogen at the time of core collapse. Archival pre-explosion Subaru Telescope Suprime-Cam and Hubble Space Telescope Wide Field Planetary Camera 2 images of the region obtained in 2009 show a coincident source that is most likely a compact massive star cluster in NGC 7331 that hosted the progenitor system. By comparing the emission properties of the source with stellar population models that incorporate interacting binary stars we estimate the age of the host cluster to be 30–300 Myr, and favor ages closer to 30 Myr in light of relatively strong Hα emission. SN 2014C is the best observed member of a class of core-collapse supernovae that fill the gap between events that interact strongly with dense, nearby environments immediately after explosion and those that never show signs of interaction. Better understanding of the frequency and nature of this intermediate population can contribute valuable information about the poorly understood final stages of stellar evolution

METAMORPHOSIS OF SN 2014C: DELAYED INTERACTION BETWEEN A HYDROGEN POOR CORE-COLLAPSE SUPERNOVA AND A NEARBY CIRCUMSTELLAR SHELL

Energy Technology Data Exchange (ETDEWEB)

Milisavljevic, D.; Margutti, R.; Kamble, A.; Patnaude, D. J.; Raymond, J. C.; Challis, P.; Drout, M. R.; Grindlay, J. E.; Kirshner, R. P.; Lunnan, R.; Miller, G. F.; Parrent, J. T.; Sanders, N. E. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA, 02138 (United States); Eldridge, J. J. [Department of Physics, University of Auckland, Private Bag 92019, Auckland (New Zealand); Fong, W. [Steward Observatory, University of Arizona, 933 N. Cherry Avenue, Tucson, AZ 85721 (United States); Bietenholz, M. [Hartebeesthoek Radio Observatory, P.O. Box 443, Krugersdorp 1740 (South Africa); Chornock, R. [Astrophysical Institute, Department of Physics and Astronomy, 251B Clippinger Lab, Ohio University, Athens, OH 45701 (United States); Fransson, C. [Oskar Klein Centre, Department of Astronomy, Stockholm University, AlbaNova, SE106 91 Stockholm (Sweden); Fesen, R. A. [Department of Physics and Astronomy, Dartmouth College, 6127 Wilder Lab, Hanover, NH 03755 (United States); Mackey, J., E-mail: dmilisav@cfa.harvard.edu [Argelander-Institut für Astronomie, Auf dem Hgel 71, D-53121 Bonn (Germany); and others

2015-12-20

We present optical observations of supernova SN 2014C, which underwent an unprecedented slow metamorphosis from H-poor type Ib to H-rich type IIn over the course of one year. The observed spectroscopic evolution is consistent with the supernova having exploded in a cavity before encountering a massive shell of the progenitor star’s stripped hydrogen envelope. Possible origins for the circumstellar shell include a brief Wolf–Rayet fast wind phase that overtook a slower red supergiant wind, eruptive ejection, or confinement of circumstellar material by external influences of neighboring stars. An extended high velocity Hα absorption feature seen in near-maximum light spectra implies that the progenitor star was not completely stripped of hydrogen at the time of core collapse. Archival pre-explosion Subaru Telescope Suprime-Cam and Hubble Space Telescope Wide Field Planetary Camera 2 images of the region obtained in 2009 show a coincident source that is most likely a compact massive star cluster in NGC 7331 that hosted the progenitor system. By comparing the emission properties of the source with stellar population models that incorporate interacting binary stars we estimate the age of the host cluster to be 30–300 Myr, and favor ages closer to 30 Myr in light of relatively strong Hα emission. SN 2014C is the best observed member of a class of core-collapse supernovae that fill the gap between events that interact strongly with dense, nearby environments immediately after explosion and those that never show signs of interaction. Better understanding of the frequency and nature of this intermediate population can contribute valuable information about the poorly understood final stages of stellar evolution.

Discovery of an Ultra-diffuse Galaxy in the Pisces--Perseus Supercluster

Science.gov (United States)

Martínez-Delgado, David; Läsker, Ronald; Sharina, Margarita; Toloba, Elisa; Fliri, Jürgen; Beaton, Rachael; Valls-Gabaud, David; Karachentsev, Igor D.; Chonis, Taylor S.; Grebel, Eva K.; Forbes, Duncan A.; Romanowsky, Aaron J.; Gallego-Laborda, J.; Teuwen, Karel; Gómez-Flechoso, M. A.; Wang, Jie; Guhathakurta, Puragra; Kaisin, Serafim; Ho, Nhung

2016-04-01

We report the discovery of DGSAT I, an ultra-diffuse, quenched galaxy located 10.°4 in projection from the Andromeda galaxy (M31). This low-surface brightness galaxy (μV = 24.8 mag arcsec-2), found with a small amateur telescope, appears unresolved in sub-arcsecond archival Subaru/Suprime-Cam images, and hence has been missed by optical surveys relying on resolved star counts, in spite of its relatively large effective radius (Re(V) = 12″) and proximity (15‧) to the well-known dwarf spheroidal galaxy And II. Its red color (V - I = 1.0), shallow Sérsic index (nV = 0.68), and the absence of detectable Hα emission are typical properties of dwarf spheroidal galaxies and suggest that it is mainly composed of old stars. Initially interpreted as an interesting case of an isolated dwarf spheroidal galaxy in the local universe, our radial velocity measurement obtained with the BTA 6 m telescope (Vh = 5450 ± 40 km s-1) shows that this system is an M31-background galaxy associated with the filament of the Pisces-Perseus supercluster. At the distance of this cluster (˜78 Mpc), DGSAT I would have an Re ˜ 4.7 kpc and MV ˜ -16.3. Its properties resemble those of the ultra-diffuse galaxies (UDGs) recently discovered in the Coma cluster. DGSAT I is the first case of these rare UDGs found in this galaxy cluster. Unlike the UDGs associated with the Coma and Virgo clusters, DGSAT I is found in a much lower density environment, which provides a fresh constraint on the formation mechanisms for this intriguing class of galaxy.

Characterization of SynCAM surface trafficking using a SynCAM derived ligand with high homophilic binding affinity

International Nuclear Information System (INIS)

Breillat, Christelle; Thoumine, Olivier; Choquet, Daniel

2007-01-01

In order to better probe SynCAM function in neurons, we produced a fusion protein between the extracellular domain of SynCAM1 and the constant fragment of human IgG (SynCAM-Fc). Whether in soluble form or immobilized on latex microspheres, the chimera bound specifically to the surface of hippocampal neurons and recruited endogenous SynCAM molecules. SynCAM-Fc was also used in combination with Quantum Dots to follow the mobility of transfected SynCAM receptors at the neuronal surface. Both immobile and highly mobile SynCAM were found. Thus, SynCAM-Fc behaves as a high affinity ligand that can be used to study the function of SynCAM at the neuronal membrane

Feasibility of a SenseCam-assisted 24-h recall to reduce under-reporting of energy intake.

Science.gov (United States)

Gemming, L; Doherty, A; Kelly, P; Utter, J; Ni Mhurchu, C

2013-10-01

The SenseCam is a camera worn on a lanyard around the neck that automatically captures point-of-view images in response to movement, heat and light (every 20-30 s). This device may enhance the accuracy of self-reported dietary intake by assisting participants' recall of food and beverage consumption. It was the objective of this study to evaluate if the wearable camera, SenseCam, can enhance the 24-h dietary recall by providing visual prompts to improve recall of food and beverage consumption. Thirteen volunteer adults in Oxford, United Kingdom, were recruited. Participants wore the SenseCam for 2 days while continuing their usual daily activities. On day 3, participants' diets were assessed using an interviewer-administered 24-h recall. SenseCam images were then shown to the participants and any additional dietary information that participants provided after viewing the images was recorded. Energy and macronutrient intakes were compared between the 24-h recall and 24-h recall+SenseCam. Data from 10 participants were included in the final analysis (8 males and 2 females), mean age 33 ± 11 years, mean BMI 25.9 ± 5.1 kg/m(2). Viewing the SenseCam images increased self-reported energy intake by approximately 1432 ± 1564 kJ or 12.5% compared with the 24-h recall alone (P=0.02). The increase was predominantly due to reporting of 41 additional foods (241 vs 282 total foods) across a range of food groups. Eight changes in portion size were made, which resulted in a negligible change to energy intake. Wearable cameras are promising method to enhance the accuracy of self-reported dietary assessment methods.

PreCam

Energy Technology Data Exchange (ETDEWEB)

Allam, Sahar S. [Fermilab; Tucker, Douglas L. [Fermilab

2015-01-01

The Dark Energy Survey (DES) will be taking the next step in probing the properties of Dark Energy and in understanding the physics of cosmic acceleration. A step towards the photometric calibration of DES is to have a quick, bright survey in the DES footprint (PreCam), using a pre-production set of the Dark Energy Camera (DECam) CCDs and a set of 100 mm×100 mm DES filters. The objective of the PreCam Survey is to create a network of calibrated DES grizY standard stars that will be used for DES nightly calibrations and to improve the DES global relative calibrations. Here, we describe the first year of PreCam observation, results, and photometric calibrations.

OPTICAL I-BAND LINEAR POLARIMETRY OF THE MAGNETAR 4U 0142+61 WITH SUBARU

Energy Technology Data Exchange (ETDEWEB)

Wang, Zhongxiang; Tziamtzis, Anestis [Shanghai Astronomical Observatory, Chinese Academy of Sciences, 80 Nandan Road, Shanghai 200030 (China); Tanaka, Yasuyuki T.; Kawabata, Koji S. [Hiroshima Astrophysical Science Center, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Wang, Chen [National Astronomical Observatories, Chinese Academy of Sciences, A20 Datun Road, Beijing 100012 (China); Fukazawa, Yasushi; Itoh, Ryosuke [Department of Physical Sciences, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8526 (Japan)

2015-12-01

Magnetars are known to have optical and/or infrared (IR) emission, but the origin of the emission is not well understood. In order to fully study their emission properties, we have carried out for the first time optical linear polarimetry of the magnetar 4U 0142+61, which has been determined from different observations to have a complicated broadband spectrum over optical and IR wavelengths. From our I-band imaging polarimetric observation, conducted with the 8.2-m Subaru telescope, we determine the degree of linear polarization to be P = 1.0 ± 3.4%, or P ≤ 5.6% (90% confidence level). Considering models that were suggested for optical emission from magnetars, we discuss the implications of our result. The upper limit measurement indicates that, differing from radio pulsars, magnetars probably would not have strongly polarized optical emission if the emission arises from their magnetosphere as suggested.

Great Escape for neglected Subaru

CERN Multimedia

2008-01-01

A CERN engineer has just come back from a challenge of a lifetime. Together with two friends he drove 4000 miles in a car they found abandoned in a car park at CERN. The Up N Atom rally team began their adventure outside the Globe in January.If you’ve ever wondered what happens to the abandoned cars that litter the car parks of CERN the answer, for one at least, could be stranger than you think. This January, an old red Subaru that had been sitting in a car park for two years made it all the way to the Gambia – with a little help from a CERN engineer! David Mcfarlane, who works in TS-LEA, and two friends from the UK have just returned from the Banjul Rally, a 4,000 mile race through Europe and North Africa. The team, appropriately named the "Up N Atoms", set off from outside the Globe on 4 January and crossed France, Spain, Morocco, the Western Sahara, Mauritania and Senegal before finally ending up in Banjul, the Gambia. A...

Demonstration of angle widening using EyeCam after laser peripheral iridotomy in eyes with angle closure.

Science.gov (United States)

Perera, Shamira A; Quek, Desmond T; Baskaran, Mani; Tun, Tin A; Kumar, Rajesh S; Friedman, David S; Aung, Tin

2010-06-01

To evaluate EyeCam in detecting changes in angle configuration after laser peripheral iridotomy (LPI) in comparison to gonioscopy, the reference standard. Prospective comparative study. Twenty-four subjects (24 eyes) with primary angle-closure glaucoma (PACG) were recruited. Gonioscopy and EyeCam (Clarity Medical Systems) imaging of all 4 angle quadrants were performed, before and 2 weeks after LPI. Images were graded according to angle structures visible by an observer masked to clinical data or the status of LPI, and were performed in a random order. Angle closure in a quadrant was defined as the inability to visualize the posterior trabecular meshwork. We determined the number of quadrants with closed angles and the mean number of clock hours of angle closure before and after LPI in comparison to gonioscopy. Using EyeCam, all 24 eyes showed at least 1 quadrant of angle widening after LPI. The mean number of clock hours of angle closure decreased significantly, from 8.15 +/- 3.47 clock hours before LPI to 1.75 +/- 2.27 clock hours after LPI (P gonioscopy showed 1.0 +/- 1.41 (95% CI, 0.43-1.57) quadrants opening from closed to open after LPI compared to 2.0 +/- 1.28 (95% CI, 1.49-2.51, P = .009) quadrants with EyeCam. Intra-observer reproducibility of grading the extent of angle closure in clock hours in EyeCam images was moderate to good (intraclass correlation coefficient 0.831). EyeCam may be used to document changes in angle configuration after LPI in eyes with PACG. Copyright 2010 Elsevier Inc. All rights reserved.

Two imaging techniques for 3D quantification of pre-cementation space for CAD/CAM crowns.

Science.gov (United States)

Rungruanganunt, Patchanee; Kelly, J Robert; Adams, Douglas J

2010-12-01

Internal three-dimensional (3D) "fit" of prostheses to prepared teeth is likely more important clinically than "fit" judged only at the level of the margin (i.e. marginal "opening"). This work evaluates two techniques for quantitatively defining 3D "fit", both using pre-cementation space impressions: X-ray microcomputed tomography (micro-CT) and quantitative optical analysis. Both techniques are of interest for comparison of CAD/CAM system capabilities and for documenting "fit" as part of clinical studies. Pre-cementation space impressions were taken of a single zirconia coping on its die using a low viscosity poly(vinyl siloxane) impression material. Calibration specimens of this material were fabricated between the measuring platens of a micrometre. Both calibration curves and pre-cementation space impression data sets were obtained by examination using micro-CT and quantitative optical analysis. Regression analysis was used to compare calibration curves with calibration sets. Micro-CT calibration data showed tighter 95% confidence intervals and was able to measure over a wider thickness range than for the optical technique. Regions of interest (e.g., lingual, cervical) were more easily analysed with optical image analysis and this technique was more suitable for extremely thin impression walls (impressions. Each has advantages and limitations but either technique has the potential for use as part of clinical studies or CAD/CAM protocol optimization. Copyright © 2010 Elsevier Ltd. All rights reserved.

A Subaru galaxy redshift survey: WFMOS survey

International Nuclear Information System (INIS)

Takada, M

2008-01-01

A planned galaxy redshift survey with the Subaru 8.2m telescope, the WFMOS survey, offers a unique opportunity for probing detailed properties of large-scale structure formation in the expanding universe by measuring clustering strength of galaxy distribution as a function of distance scale and redshift. In particular, the precise measurement of the galaxy power spectrum, combined with the cosmic microwave background experiments, allows us to obtain stringent constraints on or even determine absolute mass scales of the Big-Bang relic neutrinos as the neutrinos imprint characteristic scale- and redshift-dependent modifications onto the galaxy power spectrum shape. Here we describe the basic concept of how the galaxy clustering measurement can be used to explore the neutrino masses, with particular emphasis on advantages of the WFMOS survey over the existing low-redshift surveys such as SDSS

Optimisation Methods for Cam Mechanisms

Directory of Open Access Journals (Sweden)

Claudia–Mari Popa

2010-01-01

Full Text Available In this paper we present the criteria which represent the base of optimizing the cam mechanisms and also we perform the calculations for several types of mechanisms. We study the influence of the constructive parameters in case of the simple machines with rotation cam and follower (flat or curve of translation on the curvature radius and that of the transmission angle. As it follows, we present the optimization calculations of the cam and flat rotation follower mechanisms, as well as the calculations for optimizing the cam mechanisms by circular groove followers’ help. For an easier interpretation of the results, we have visualized the obtained cam in AutoCAD according to the script files generated by a calculation program.

Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1.

Science.gov (United States)

Park, Kellie A; Ribic, Adema; Laage Gaupp, Fabian M; Coman, Daniel; Huang, Yuegao; Dulla, Chris G; Hyder, Fahmeed; Biederer, Thomas

2016-07-13

Select adhesion proteins control the development of synapses and modulate their structural and functional properties. Despite these important roles, the extent to which different synapse-organizing mechanisms act across brain regions to establish connectivity and regulate network properties is incompletely understood. Further, their functional roles in different neuronal populations remain to be defined. Here, we applied diffusion tensor imaging (DTI), a modality of magnetic resonance imaging (MRI), to map connectivity changes in knock-out (KO) mice lacking the synaptogenic cell adhesion protein SynCAM 1. This identified reduced fractional anisotropy in the hippocampal CA3 area in absence of SynCAM 1. In agreement, mossy fiber refinement in CA3 was impaired in SynCAM 1 KO mice. Mossy fibers make excitatory inputs onto postsynaptic specializations of CA3 pyramidal neurons termed thorny excrescences and these structures were smaller in the absence of SynCAM 1. However, the most prevalent targets of mossy fibers are GABAergic interneurons and SynCAM 1 loss unexpectedly reduced the number of excitatory terminals onto parvalbumin (PV)-positive interneurons in CA3. SynCAM 1 KO mice additionally exhibited lower postsynaptic GluA1 expression in these PV-positive interneurons. These synaptic imbalances in SynCAM 1 KO mice resulted in CA3 disinhibition, in agreement with reduced feedforward inhibition in this network in the absence of SynCAM 1-dependent excitatory drive onto interneurons. In turn, mice lacking SynCAM 1 were impaired in memory tasks involving CA3. Our results support that SynCAM 1 modulates excitatory mossy fiber inputs onto both interneurons and principal neurons in the hippocampal CA3 area to balance network excitability. This study advances our understanding of synapse-organizing mechanisms on two levels. First, the data support that synaptogenic proteins guide connectivity and can function in distinct brain regions even if they are expressed broadly

The Moving Group Targets of the SEEDS High-contrast Imaging Survey of Exoplanets and Disks: Results and Observations from the First Three Years

NARCIS (Netherlands)

Brandt, T.D.; et al., [Unknown; Thalmann, C.

2014-01-01

We present results from the first three years of observations of moving group (MG) targets in the Strategic Exploration of Exoplanets and Disks with Subaru (SEEDS) high-contrast imaging survey of exoplanets and disks using the Subaru telescope. We achieve typical contrasts of ~105 at 1'' and ~106

Utilizing optical coherence tomography for CAD/CAM of indirect dental restorations

Science.gov (United States)

Chityala, Ravishankar; Vidal, Carola; Jones, Robert

Optical Coherence Tomography (OCT) has seen broad application in dentistry including early carious lesion detection and imaging defects in resin composite restorations. This study investigates expanding the clinical usefulness by investigating methods to use OCT for obtaining three-dimensional (3D) digital impressions, which can be integrated to CAD/CAM manufacturing of indirect restorations. 3D surface topography `before' and `after' a cavity preparation was acquired by an intraoral cross polarization swept source OCT (CP-OCT) system with a Micro-Electro-Mechanical System (MEMS) scanning mirror. Image registration and segmentation methods were used to digitally construct a replacement restoration that modeled the original surface morphology of a hydroxyapatite sample. After high resolution additive manufacturing (e.g. polymer 3D printing) of the replacement restoration, micro-CT imaging was performed to examine the marginal adaptation. This study establishes the protocol for further investigation of integrating OCT with CAD/CAM of indirect dental restorations.

Modeling biophysical properties of broad-leaved stands in the hyrcanian forests of Iran using fused airborne laser scanner data and ultraCam-D images

Science.gov (United States)

Mohammadi, Jahangir; Shataee, Shaban; Namiranian, Manochehr; Næsset, Erik

2017-09-01

Inventories of mixed broad-leaved forests of Iran mainly rely on terrestrial measurements. Due to rapid changes and disturbances and great complexity of the silvicultural systems of these multilayer forests, frequent repetition of conventional ground-based plot surveys is often cost prohibitive. Airborne laser scanning (ALS) and multispectral data offer an alternative or supplement to conventional inventories in the Hyrcanian forests of Iran. In this study, the capability of a combination of ALS and UltraCam-D data to model stand volume, tree density, and basal area using random forest (RF) algorithm was evaluated. Systematic sampling was applied to collect field plot data on a 150 m × 200 m sampling grid within a 1100 ha study area located at 36°38‧- 36°42‧N and 54°24‧-54°25‧E. A total of 308 circular plots (0.1 ha) were measured for calculation of stand volume, tree density, and basal area per hectare. For each plot, a set of variables was extracted from both ALS and multispectral data. The RF algorithm was used for modeling of the biophysical properties using ALS and UltraCam-D data separately and combined. The results showed that combining the ALS data and UltraCam-D images provided a slight increase in prediction accuracy compared to separate modeling. The RMSE as percentage of the mean, the mean difference between observed and predicted values, and standard deviation of the differences using a combination of ALS data and UltraCam-D images in an independent validation at 0.1-ha plot level were 31.7%, 1.1%, and 84 m3 ha-1 for stand volume; 27.2%, 0.86%, and 6.5 m2 ha-1 for basal area, and 35.8%, -4.6%, and 77.9 n ha-1 for tree density, respectively. Based on the results, we conclude that fusion of ALS and UltraCam-D data may be useful for modeling of stand volume, basal area, and tree density and thus gain insights into structural characteristics in the complex Hyrcanian forests.

Expression, crystallization and preliminary diffraction studies of the Pseudomonas putida cytochrome P450cam operon repressor CamR

International Nuclear Information System (INIS)

Maenaka, Katsumi; Fukushi, Kouji; Aramaki, Hironori; Shirakihara, Yasuo

2005-01-01

The P. putida cytochrome P450cam operon repressor CamR has been expressed in E. coli and crystallized in space group P2 1 2 1 2. The Pseudomonas putida cam repressor (CamR) is a homodimeric protein that binds to the camO DNA operator to inhibit the transcription of the cytochrome P450cam operon camDCAB. CamR has two functional domains: a regulatory domain and a DNA-binding domain. The binding of the inducer d-camphor to the regulatory domain renders the DNA-binding domain unable to bind camO. Native CamR and its selenomethionyl derivative have been overproduced in Escherichia coli and purified. Native CamR was crystallized under the following conditions: (i) 12–14% PEG 4000, 50 mM Na PIPES, 0.1 M KCl, 1% glycerol pH 7.3 at 288 K with and without camphor and (ii) 1.6 M P i , 50 mM Na PIPES, 2 mM camphor pH 6.7 at 278 K. The selenomethionyl derivative CamR did not crystallize under either of these conditions, but did crystallize using 12.5% PEG MME 550, 25 mM Na PIPES, 2.5 mM MgCl 2 pH 7.3 at 298 K. Preliminary X-ray diffraction studies revealed the space group to be orthorhombic (P2 1 2 1 2), with unit-cell parameters a = 48.0, b = 73.3, c = 105.7 Å. Native and selenomethionyl derivative data sets were collected to 3 Å resolution at SPring-8 and the Photon Factory

DISCOVERY OF AN ULTRA-DIFFUSE GALAXY IN THE PISCES-PERSEUS SUPERCLUSTER

Energy Technology Data Exchange (ETDEWEB)

Martínez-Delgado, David; Grebel, Eva K. [Astronomisches Rechen-Institut, Zentrum für Astronomie der Universität Heidelberg, Mönchhofstr. 12–14, D-69120 Heidelberg (Germany); Läsker, Ronald [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany); Sharina, Margarita; Karachentsev, Igor D. [Special Astrophysical Observatory, Russian Academy of Sciences (Russian Federation); Toloba, Elisa; Romanowsky, Aaron J. [University of California Observatories, 1156 High Street, Santa Cruz, CA 95064 (United States); Fliri, Jürgen [Instituto de Astrofísica de Canarias, Vía Láctea s/n, E-38200 La Laguna, Tenerife (Spain); Beaton, Rachael [The Observatories of the Carnegie Institutions for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Valls-Gabaud, David [LERMA, CNRS UMR 8112, Observatoire de Paris, 61 Avenue de l’Observatoire, F-75014 Paris (France); Chonis, Taylor S. [Department of Astronomy, University of Texas at Austin, 2515 Speedway, Stop C1400, Austin, TX 78712 (United States); Forbes, Duncan A. [Center for Astrophysics and Supercomputing, Swinburne University, Hawthorn VIC 3122 (Australia); Gallego-Laborda, J. [Fosca Nit Observatory, Montsec Astronomical Park, Ager (Spain); Teuwen, Karel [Remote Observatories Southern Alpes, Verclause (France); Gómez-Flechoso, M. A. [Departamento de Matemática Aplicada (Biomatemática), Universidad Complutense de Madrid, E-28040 Madrid (Spain); and others

2016-04-15

We report the discovery of DGSAT I, an ultra-diffuse, quenched galaxy located 10.°4 in projection from the Andromeda galaxy (M31). This low-surface brightness galaxy (μ{sub V} = 24.8 mag arcsec{sup −2}), found with a small amateur telescope, appears unresolved in sub-arcsecond archival Subaru/Suprime-Cam images, and hence has been missed by optical surveys relying on resolved star counts, in spite of its relatively large effective radius (R{sub e}(V) = 12″) and proximity (15′) to the well-known dwarf spheroidal galaxy And II. Its red color (V − I = 1.0), shallow Sérsic index (n{sub V} = 0.68), and the absence of detectable Hα emission are typical properties of dwarf spheroidal galaxies and suggest that it is mainly composed of old stars. Initially interpreted as an interesting case of an isolated dwarf spheroidal galaxy in the local universe, our radial velocity measurement obtained with the BTA 6 m telescope (V{sub h} = 5450 ± 40 km s{sup −1}) shows that this system is an M31-background galaxy associated with the filament of the Pisces-Perseus supercluster. At the distance of this cluster (∼78 Mpc), DGSAT I would have an R{sub e} ∼ 4.7 kpc and M{sub V} ∼ −16.3. Its properties resemble those of the ultra-diffuse galaxies (UDGs) recently discovered in the Coma cluster. DGSAT I is the first case of these rare UDGs found in this galaxy cluster. Unlike the UDGs associated with the Coma and Virgo clusters, DGSAT I is found in a much lower density environment, which provides a fresh constraint on the formation mechanisms for this intriguing class of galaxy.

The Double Galaxy Cluster A2465. III. X-Ray and Weak-lensing Observations

Energy Technology Data Exchange (ETDEWEB)

Wegner, Gary A. [Department of Physics and Astronomy, 6127 Wilder Laboratory, Hanover, NH 03745 (United States); Umetsu, Keiichi; Molnar, Sandor M. [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Nonino, Mario [INAF/Osservatorio Astronomico di Trieste, via G. B. Tiepolo 11, 34143 Trieste (Italy); Medezinski, Elinor [Department of Astrophysical Sciences, 4 Ivy Lane, Princeton, NJ 08544 (United States); Andrade-Santos, Felipe; Bogdan, Akos; Lovisari, Lorenzo; Forman, William R.; Jones, Christine, E-mail: gary.wegner@dartmouth.edu [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

2017-07-20

We report Chandra X-ray observations and optical weak-lensing measurements from Subaru/Suprime-Cam images of the double galaxy cluster A2465 ( z = 0.245). The X-ray brightness data are fit to a β model to obtain the radial gas density profiles of the northeast (NE) and southwest (SW) subcomponents, which are seen to differ in structure. We determine core radii, central temperatures, the gas masses within r {sub 500c}, and the total masses for the broader NE and sharper SW components assuming hydrostatic equilibrium. There is no large X-ray excess between the two components. The central entropy of the NE subcluster is about two times higher than the SW. Along with its structural properties and an apparent radio halo that is a sign of a merger, this suggests that the NE component has undergone merging on its own. The weak-lensing analysis gives virial masses for each substructure, which compare well with earlier dynamical results. The derived outer mass contours of the SW sub-component from weak lensing are more irregular and extended than those of the NE. Although there is a weak enhancement and small offsets between X-ray gas and mass centers from weak lensing, the lack of large amounts of gas between the two subclusters indicates that A2465 is in a pre-merger state. We discuss star formation enhancement in this system resulting from its dynamics and shock-induced star formation scenarios. A dynamical model that is consistent with the observed cluster data, based on the FLASH program and the radial infall model, is constructed, where the subclusters currently separated by ∼1.2 Mpc are approaching each other at ∼2000 km s{sup −1} and will meet in ∼0.4 Gyr.

Ecophysiology of Crassulacean Acid Metabolism (CAM).

Science.gov (United States)

Lüttge, Ulrich

2004-06-01

Crassulacean Acid Metabolism (CAM) as an ecophysiological modification of photosynthetic carbon acquisition has been reviewed extensively before. Cell biology, enzymology and the flow of carbon along various pathways and through various cellular compartments have been well documented and discussed. The present attempt at reviewing CAM once again tries to use a different approach, considering a wide range of inputs, receivers and outputs. Input is given by a network of environmental parameters. Six major ones, CO(2), H(2)O, light, temperature, nutrients and salinity, are considered in detail, which allows discussion of the effects of these factors, and combinations thereof, at the individual plant level ('physiological aut-ecology'). Receivers of the environmental cues are the plant types genotypes and phenotypes, the latter including morphotypes and physiotypes. CAM genotypes largely remain 'black boxes', and research endeavours of genomics, producing mutants and following molecular phylogeny, are just beginning. There is no special development of CAM morphotypes except for a strong tendency for leaf or stem succulence with large cells with big vacuoles and often, but not always, special water storage tissues. Various CAM physiotypes with differing degrees of CAM expression are well characterized. Output is the shaping of habitats, ecosystems and communities by CAM. A number of systems are briefly surveyed, namely aquatic systems, deserts, salinas, savannas, restingas, various types of forests, inselbergs and paramós. While quantitative census data for CAM diversity and biomass are largely missing, intuition suggests that the larger CAM domains are those systems which are governed by a network of interacting stress factors requiring versatile responses and not systems where a single stress factor strongly prevails. CAM is noted to be a strategy for variable, flexible and plastic niche occupation rather than lush productivity. 'Physiological syn-ecology' reveals

Complementary and alternative medicine use of women with breast cancer : Self-help CAM attracts other women than guided CAM therapies

NARCIS (Netherlands)

Lo-Fo-Wong, Deborah N. N.; Ranchor, Adelita V.; de Haes, Hanneke C. J. M.; Sprangers, Mirjam A. G.; Henselmans, Inge

2012-01-01

Objective: Examine stability of use of complementary and alternative medicine (CAM) of breast cancer patients, reasons for CAM use, and sociodemographic, clinical, and psychological predictors of CAM use. Methods: CAM use was assessed after adjuvant therapy and six months later. Following the CAM

Complementary and alternative medicine use of women with breast cancer: Self-help CAM attracts other women than guided CAM therapies

NARCIS (Netherlands)

Lo-Fo-Wong, Deborah N. N.; Ranchor, Adelita V.; de Haes, Hanneke C. J. M.; Sprangers, Mirjam A. G.; Henselmans, Inge

2012-01-01

Objective: Examine stability of use of complementary and alternative medicine (CAM) of breast cancer patients, reasons for CAM use, and sociodemographic, clinical, and psychological predictors of CAM use. Methods: CAM use was assessed after adjuvant therapy and six months later. Following the CAM

LYMAN BREAK GALAXIES AT z ∼ 1.8-2.8: GALEX/NUV IMAGING OF THE SUBARU DEEP FIELD

International Nuclear Information System (INIS)

Ly, Chun; Malkan, Matthew A.; Woo, Jong-Hak; Treu, Tommaso; Currie, Thayne; Hayashi, Masao; Shimasaku, Kazuhiro; Yoshida, Makiko; Kashikawa, Nobunari; Motohara, Kentaro

2009-01-01

A photometric sample of ∼8000 V C i'z' optical data with deep GALEX/NUV imaging of the Subaru Deep Field. Follow-up spectroscopy confirmed 24 LBGs at 1.5 ∼< z ∼< 2.7. Among the optical spectra, 12 have Lyα emission with rest-frame equivalent widths of ∼5-60 A. The success rate for identifying LBGs as NUV-dropouts at 1.5 < z < 2.7 is 86%. The rest-frame UV (1700 A) luminosity function (LF) is constructed from the photometric sample with corrections for stellar contamination and z < 1.5 interlopers (lower limits). The LF is 1.7 ± 0.1 (1.4 ± 0.1 with a hard upper limit on stellar contamination) times higher than those of z ∼ 2 BXs and z ∼ 3 LBGs. Three explanations were considered, and it is argued that significantly underestimating low-z contamination or effective comoving volume is unlikely: the former would be inconsistent with the spectroscopic sample at 93% confidence, and the second explanation would not resolve the discrepancy. The third scenario is that different photometric selection of the samples yields nonidentical galaxy populations, such that some BX galaxies are LBGs and vice versa. This argument is supported by a higher surface density of LBGs at all magnitudes while the redshift distribution of the two populations is nearly identical. This study, when combined with other star formation rate (SFR) density UV measurements from LBG surveys, indicates that there is a rise in the SFR density: a factor of 3-6 (3-10) increase from z ∼ 5 (z ∼ 6) to z ∼ 2, followed by a decrease to z ∼ 0. This result, along with past sub-mm studies that find a peak at z ∼ 2 in their redshift distribution, suggests that z ∼ 2 is the epoch of peak star formation.

Diagenetic Features Analyzed by ChemCam/Curiosity at Pahrump Hills, Gale Crater, Mars

Science.gov (United States)

Nachon, M.; Mangold, N.; Cousin, A.; Forni, O.; Anderson, R. B.; Blank, J. G.; Calef, F.; Clegg, S.; Fabre, C.; Fisk, M.;

Experimental Study on Revetec Engine Cam Performance

International Nuclear Information System (INIS)

Gasim, Maisara Mohyeldin; Chui, Lee Giok; Anwar, Khirul Azhar bin

2012-01-01

In Revetec engine (three-lobed) cam replaces the crankshaft to convert the reciprocating motion of the engine piston, to a rotating motion in the drive line. Since the cam controls the piston movement, the cam profile has a great effect on engine performance. In this paper an experimental study was done to a (three- lobed) cam with Cycloidal motion profile but with different ratios between the base circle radius of the cam and the radius of the roller follower. DEWESoft was used to find the displacement and the vibration of the piston, and compare the actual results from the test with the theoretical results from the cam profile equation. The results showed that there is a periods of miss contact between the follower and the cam when the ratio between the base circle radius of the cam and the radius of the roller follower is less than a certain value, and also increasing of vibration. The suggested ratio between the cam and follower radius is to be more than 2:1.

High-resolution optical imaging of the core of the globular cluster M15 with FastCam

Science.gov (United States)

Díaz-Sánchez, Anastasio; Pérez-Garrido, Antonio; Villó, Isidro; Rebolo, Rafael; Pérez-Prieto, Jorge A.; Oscoz, Alejandro; Hildebrandt, Sergi R.; López, Roberto; Rodríguez, Luis F.

2012-07-01

We present high-resolution I -band imaging of the core of the globular cluster M15 obtained at the 2.5-m Nordic Optical Telescope with FastCam, a low readout noise L3CCD-based instrument. Short exposure times (30 ms) were used to record 200 000 images (512 × 512 pixels each) over a period of 2 h and 43 min. The lucky imaging technique was then applied to generate a final image of the cluster centre with full width at half-maximum ˜0.1 arcsec and 13 × 13 arcsec 2 field of view. We obtained a catalogue of objects in this region with a limiting magnitude of I = 19.5. I -band photometry and astrometry are reported for 1181 stars. This is the deepest I -band observation of the M15 core at this spatial resolution. Simulations show that crowding is limiting the completeness of the catalogue. At shorter wavelengths, a similar number of objects have been reported using Hubble Space Telescope (HST )/Wide Field Planetary Camera observations of the same field. The cross-match with the available HST catalogues allowed us to produce colour-magnitude diagrams where we identify new blue straggler star candidates and previously known stars of this class.

Alignment for new Subaru ring

International Nuclear Information System (INIS)

Zhang, Ch.; Matsui, S.; Hashimoto, S.

1999-01-01

The New SUBARU is a synchrotron light source being constructed at the SPring-8 site. The main facility is a 1.5 GeV electron storage ring that provides light beam in the region from VUV to soft X-ray using SPring-8's 1 GeV linac as an injector. The ring, with a circumference of about 119 meters, is composed of six bending cells. Each bending cell has two normal dipoles of 34 degree and one inverse dipole of -8 degree. The ring has six straight sections: two very long straight sections for a 11-m long undulator and an optical klystron, four short straight sections for a 2.3-m undulator, a super-conducting wiggler, rf cavity and injection, etc. The magnets of the storage ring are composed of 12 dipoles (BMs), 6 invert dipoles (BIs), 56 quadrupoles and 44 sextupoles, etc. For the magnet alignment, positions of the dipoles (the BMs and BIs) are determined by network survey method. The multipoles, which are mounted on girders between the dipoles, are aligned with a laser-CCD camera system. This article presents the methodology used to position the different components and particularly to assure the precise alignment of the multipoles. (authors)

Subaru FATS (fault tracking system)

Science.gov (United States)

Winegar, Tom W.; Noumaru, Junichi

2000-07-01

The Subaru Telescope requires a fault tracking system to record the problems and questions that staff experience during their work, and the solutions provided by technical experts to these problems and questions. The system records each fault and routes it to a pre-selected 'solution-provider' for each type of fault. The solution provider analyzes the fault and writes a solution that is routed back to the fault reporter and recorded in a 'knowledge-base' for future reference. The specifications of our fault tracking system were unique. (1) Dual language capacity -- Our staff speak both English and Japanese. Our contractors speak Japanese. (2) Heterogeneous computers -- Our computer workstations are a mixture of SPARCstations, Macintosh and Windows computers. (3) Integration with prime contractors -- Mitsubishi and Fujitsu are primary contractors in the construction of the telescope. In many cases, our 'experts' are our contractors. (4) Operator scheduling -- Our operators spend 50% of their work-month operating the telescope, the other 50% is spent working day shift at the base facility in Hilo, or day shift at the summit. We plan for 8 operators, with a frequent rotation. We need to keep all operators informed on the current status of all faults, no matter the operator's location.

AVERAGE METALLICITY AND STAR FORMATION RATE OF Ly{alpha} EMITTERS PROBED BY A TRIPLE NARROWBAND SURVEY

Energy Technology Data Exchange (ETDEWEB)

Nakajima, Kimihiko; Shimasaku, Kazuhiro; Ono, Yoshiaki; Okamura, Sadanori [Department of Astronomy, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Ouchi, Masami [Institute for the Physics and Mathematics of the Universe (IPMU), TODIAS, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8583 (Japan); Lee, Janice C.; Ly, Chun [Observatories of the Carnegie Institution of Washington, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Foucaud, Sebastien [Department of Earth Sciences, National Taiwan Normal University, No. 88, Tingzhou Road, Sec. 4, Taipei 11677, Taiwan (China); Dale, Daniel A. [Department of Physics and Astronomy, University of Wyoming, Laramie, WY (United States); Salim, Samir [Department of Astronomy, Indiana University, Bloomington, IN (United States); Finn, Rose [Department of Physics, Siena College, Loudonville, NY (United States); Almaini, Omar, E-mail: nakajima@astron.s.u-tokyo.ac.jp [School of Physics and Astronomy, University of Nottingham, Nottingham (United Kingdom)

2012-01-20

We present the average metallicity and star formation rate (SFR) of Ly{alpha} emitters (LAEs) measured from our large-area survey with three narrowband (NB) filters covering the Ly{alpha}, [O II]{lambda}3727, and H{alpha}+[N II] lines of LAEs at z = 2.2. We select 919 z = 2.2 LAEs from Subaru/Suprime-Cam NB data in conjunction with Magellan/IMACS spectroscopy. Of these LAEs, 561 and 105 are observed with KPNO/NEWFIRM near-infrared NB filters whose central wavelengths are matched to redshifted [O II] and H{alpha} nebular lines, respectively. By stacking the near-infrared images of the LAEs, we successfully obtain average nebular-line fluxes of LAEs, the majority of which are too faint to be identified individually by NB imaging or deep spectroscopy. The stacked object has an H{alpha} luminosity of 1.7 Multiplication-Sign 10{sup 42} erg s{sup -1} corresponding to an SFR of 14 M{sub Sun} yr{sup -1}. We place, for the first time, a firm lower limit to the average metallicity of LAEs of Z {approx}> 0.09 Z{sub Sun} (2{sigma}) based on the [O II]/(H{alpha}+[N II]) index together with photoionization models and empirical relations. This lower limit of metallicity rules out the hypothesis that LAEs, so far observed at z {approx} 2, are extremely metal-poor (Z < 2 Multiplication-Sign 10{sup -2} Z{sub Sun }) galaxies at the 4{sigma} level. This limit is higher than a simple extrapolation of the observed mass-metallicity relation of z {approx} 2 UV-selected galaxies toward lower masses (5 Multiplication-Sign 10{sup 8} M{sub Sun }), but roughly consistent with a recently proposed fundamental mass-metallicity relation when the LAEs' relatively low SFR is taken into account. The H{alpha} and Ly{alpha} luminosities of our NB-selected LAEs indicate that the escape fraction of Ly{alpha} photons is {approx}12%-30%, much higher than the values derived for other galaxy populations at z {approx} 2.

AVERAGE METALLICITY AND STAR FORMATION RATE OF Lyα EMITTERS PROBED BY A TRIPLE NARROWBAND SURVEY

International Nuclear Information System (INIS)

Nakajima, Kimihiko; Shimasaku, Kazuhiro; Ono, Yoshiaki; Okamura, Sadanori; Ouchi, Masami; Lee, Janice C.; Ly, Chun; Foucaud, Sebastien; Dale, Daniel A.; Salim, Samir; Finn, Rose; Almaini, Omar

2012-01-01

We present the average metallicity and star formation rate (SFR) of Lyα emitters (LAEs) measured from our large-area survey with three narrowband (NB) filters covering the Lyα, [O II]λ3727, and Hα+[N II] lines of LAEs at z = 2.2. We select 919 z = 2.2 LAEs from Subaru/Suprime-Cam NB data in conjunction with Magellan/IMACS spectroscopy. Of these LAEs, 561 and 105 are observed with KPNO/NEWFIRM near-infrared NB filters whose central wavelengths are matched to redshifted [O II] and Hα nebular lines, respectively. By stacking the near-infrared images of the LAEs, we successfully obtain average nebular-line fluxes of LAEs, the majority of which are too faint to be identified individually by NB imaging or deep spectroscopy. The stacked object has an Hα luminosity of 1.7 × 10 42 erg s –1 corresponding to an SFR of 14 M ☉ yr –1 . We place, for the first time, a firm lower limit to the average metallicity of LAEs of Z ∼> 0.09 Z ☉ (2σ) based on the [O II]/(Hα+[N II]) index together with photoionization models and empirical relations. This lower limit of metallicity rules out the hypothesis that LAEs, so far observed at z ∼ 2, are extremely metal-poor (Z –2 Z ☉ ) galaxies at the 4σ level. This limit is higher than a simple extrapolation of the observed mass-metallicity relation of z ∼ 2 UV-selected galaxies toward lower masses (5 × 10 8 M ☉ ), but roughly consistent with a recently proposed fundamental mass-metallicity relation when the LAEs' relatively low SFR is taken into account. The Hα and Lyα luminosities of our NB-selected LAEs indicate that the escape fraction of Lyα photons is ∼12%-30%, much higher than the values derived for other galaxy populations at z ∼ 2.

The hen's egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ.

Science.gov (United States)

McKenzie, Barbara; Kay, Graeme; Matthews, Kerr H; Knott, Rachel M; Cairns, Donald

2015-07-25

A modified hen's egg chorioallantoic membrane (HET-CAM) test has been developed, combining ImageJ analysis with Adobe(®) Photoshop(®). The irritation potential of an ophthalmic medicine can be quantified using this method, by monitoring damage to blood vessels. The evaluation of cysteamine containing hyaluronate gel is reported. The results demonstrated that the novel gel formulation is non-irritant to the ocular tissues, in line with saline solution (negative control). In conclusion, the modification of the established HET-CAM test can quantify the damage to minute blood vessels. These results offer the possibility to formulate cysteamine in an ocular applicable gel formulation. Copyright © 2015 Elsevier B.V. All rights reserved.

Should CAM and CAM Training Programs Be Included in the Curriculum of Schools That Provide Health Education?

Directory of Open Access Journals (Sweden)

2016-12-01

Full Text Available Objectives: This study aimed to determine the knowledge levels and attitudes of School of Health and Vocational School of Health students toward complementary and alternative medicine (CAM. Methods: Three hundred thirty-three (333 students studying at the Mehmet Akif Ersoy University School of Health and the Golhisar Vocational School of Health in Burdur, Turkey, were included in the study. Research data were collected by using a survey method based on the expressed opinions of the participants. Results: Of the participants, 69.7% were female and 97% were single (unmarried. Of cigarette users and those with chronic illnesses, 46.8% and 47.8%, respectively, used CAM. Those using CAM were statistically more likely to be female (P < 0.021, to have higher grades (P < 0.007, to be single (P < 0.005, to be vocational school of health graduates (P < 0.008, and to have fathers at work (P < 0.021. While 9.6% of the students thought CAM to be nonsense, 10.8% thought that the methods of CAM should be tried before consulting a doctor. Conclusion: A majority of the students in the study population were found to use complementary and alternative medicine, but that they lacked information about its methods. As a way to address this, CAM should be included in the curriculum of schools that provide health education, and CAM training programs should be given to healthcare professionals to improve their knowledge of CAM. In Turkey, many more studies should be performed to determine nurses’ and doctors’ knowledge of and attitudes about CAM methods so that they can give correct guidance to society and take more active responsibility in improving patient safety.

CAMS achievements in 1995

International Nuclear Information System (INIS)

Berg, Oe.; Fantoni, P.; Iguchi, Y.; Meyer, G.; Soerensen, A.; Dyck, C. van.

1996-01-01

CAMS (Computerized Accident Management Support) is a system being developed as a joint research activity at the Halden Reactor Project with additional financing from the Swedish Nuclear Inspectorate (SKI) and the Nordic NKS/RAK-2 project. Three types of users are envisaged: the staff in the control room, the staff in the technical support centre and the staff at a national emergency centre. It is still an experimental system. The Swedish Nuclear Inspectorate kindly accepted to test CAMS at a safety exercise on the 4th of May, 1995. CAMS is designed assuming automatic data transfer from the plant. Missing the data link, a simulator running in the next room was updated now and then with data received by phone. As seen from CAMS, it did not matter if the data came from a fake plant or from a real plant, except that the data were delayed. Overall, it seemed that CAMS can be a very important tool for a national authority. A data link from the plant would increase its usefulness. Several comments on design features were collected and will be used to improve the system. The model needs more inputs to control the main parameters, and a larger repertoire of fault conditions should be put into the model. In the second half of 1995 the work on CAMS has concentrated upon designing new modules for signal validation, tracking simulation and state identification. This will provide better capabilities for on-line monitoring and assessment of the plant state. Further, it has been proposed to introduce Probabilistic Safety Assessment (PSA) to assist in risk monitoring. A first prototype has been made on a personal computer showing the main features of such a PSA module. (au)

*Abstracts - 7th IN-CAM Research Symposium, Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety - November 2012.

Science.gov (United States)

Boon, Heather; Verhoef, Marja J

2012-10-23

Abstract The following are abstracts of oral and poster presentations given at the 7th IN-CAM Research Symposium - Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety, and the 4th HomeoNet Research Forum, a pre-Symposium event. The IN-CAM Research Symposium was held November 2 to 4, 2012 at the Leslie Dan Faculty of Pharmacy, University of Toronto, in Toronto, Ontario, Canada. For more information, please visit: www.incamresearch.ca.

Cam deformity and the omega angle, a novel quantitative measurement of femoral head-neck morphology: a 3D CT gender analysis in asymptomatic subjects

International Nuclear Information System (INIS)

Mascarenhas, Vasco V.; Gaspar, Augusto; Rego, Paulo; Dantas, Pedro; Soldado, Francisco; Consciencia, Jose G.

2017-01-01

Our objectives were to use 3D computed tomography (CT) to define head-neck morphologic gender-specific and normative parameters in asymptomatic individuals and use the omega angle (Ω ) to provide quantification data on the location and radial extension of a cam deformity. We prospectively included 350 individuals and evaluated 188 asymptomatic hips that underwent semiautomated CT analysis. Different thresholds of alpha angle (α ) were considered in order to analyze cam morphology and determine Ω . We calculated overall and gender-specific parameters for imaging signs of cam morphology (Ω and circumferential α ). The 95 % reference interval limits were beyond abnormal thresholds found in the literature for cam morphology. Specifically, α at 3/1 oclock were 46.9 /60.8 overall, 51.8 /65.4 for men and 45.7 /55.3 for women. Cam prevalence, magnitude, location, and epicenter were significantly gender different. Increasing α correlated with higher Ω , meaning that higher angles correspond to larger cam deformities. Hip morphometry measurements in this cohort of asymptomatic individuals extended beyond current thresholds used for the clinical diagnosis of cam deformity, and α was found to vary both by gender and measurement location. These results suggest that α measurement is insufficient for the diagnosis of cam deformity. Enhanced morphometric evaluation, including 3D imaging and Ω , may enable a more accurate diagnosis. (orig.)

Cam deformity and the omega angle, a novel quantitative measurement of femoral head-neck morphology: a 3D CT gender analysis in asymptomatic subjects

Energy Technology Data Exchange (ETDEWEB)

Mascarenhas, Vasco V.; Gaspar, Augusto [Hospital da Luz, MSK imaging Unit (UIME), Imaging Center, Lisbon (Portugal); Rego, Paulo [Hospital da Luz, Department of Orthopaedic Surgery, Lisbon (Portugal); Dantas, Pedro [Hospital CUF Descobertas, Lisbon (Portugal); Soldado, Francisco [Universitat de Barcelona, Hospital Sant Joan de Deu, Barcelona (Spain); Consciencia, Jose G. [NOVA Medical School, Lisbon (Portugal)

2017-05-15

Our objectives were to use 3D computed tomography (CT) to define head-neck morphologic gender-specific and normative parameters in asymptomatic individuals and use the omega angle (Ω ) to provide quantification data on the location and radial extension of a cam deformity. We prospectively included 350 individuals and evaluated 188 asymptomatic hips that underwent semiautomated CT analysis. Different thresholds of alpha angle (α ) were considered in order to analyze cam morphology and determine Ω . We calculated overall and gender-specific parameters for imaging signs of cam morphology (Ω and circumferential α ). The 95 % reference interval limits were beyond abnormal thresholds found in the literature for cam morphology. Specifically, α at 3/1 oclock were 46.9 /60.8 overall, 51.8 /65.4 for men and 45.7 /55.3 for women. Cam prevalence, magnitude, location, and epicenter were significantly gender different. Increasing α correlated with higher Ω , meaning that higher angles correspond to larger cam deformities. Hip morphometry measurements in this cohort of asymptomatic individuals extended beyond current thresholds used for the clinical diagnosis of cam deformity, and α was found to vary both by gender and measurement location. These results suggest that α measurement is insufficient for the diagnosis of cam deformity. Enhanced morphometric evaluation, including 3D imaging and Ω , may enable a more accurate diagnosis. (orig.)

Thyroid Disease and Complementary and Alternative Medicine (CAM)

Science.gov (United States)

... Alternative Medicine in Thyroid Disease Complementary and Alternative Medicine in Thyroid Disease (CAM) WHAT IS COMPLEMENTARY AND ALTERNATIVE MEDICINE (CAM)? Complementary and Alternative Medicine (CAM) is defined ...

Effect of denture cleaning on abrasion resistance and surface topography of polymerized CAD CAM acrylic resin denture base.

Science.gov (United States)

Shinawi, Lana Ahmed

2017-05-01

The application of computer-aided design computer-aided manufacturing (CAD CAM) technology in the fabrication of complete dentures, offers numerous advantages as it provides optimum fit and eliminates polymerization shrinkage of the acrylic base. Additionally, the porosity and surface roughness of CAD CAM resins is less compared to conventionally processed resins which leads to a decrease in the adhesion of bacteria on the denture base, which is associated with many conditions including halitosis and aspiration pneumonia in elderly denture wearers. To evaluate the influence of tooth brushing with dentifrices on CAD CAM resin blocks in terms of abrasion resistance, surface roughness and scanning electron photomicrography. This experimental study was carried out at the Faculty of Dentistry of King Abdulaziz University during 2016. A total of 40 rectangular shaped polymerized CAD CAM resin samples were subjected to 40.000 and 60.000 brushing strokes under a 200-gram vertical load simulating three years of tooth brushing strokes using commercially available denture cleaning dentifrice. Data were analyzed by SPSS version 20, using descriptive statistics and ANOVA. ANOVA test revealed a statistical significant weight loss of CAD CAM acrylic resin denture base specimens following 40.000 and 60.000 brushing strokes as well as a statistical significant change (p=0.0.5) in the surface roughness following brushing. The CAD CAM resin samples SEM baseline imaging revealed a relatively smooth homogenous surface, but following 40,000 and 60,000 brushing strokes, imaging displayed the presence of small scratches on the surface. CAD CAM resin displayed a homogenous surface initially with low surface roughness that was significantly affected following simulating three years of manual brushing, but despite the significant weight loss, the findings are within the clinically acceptable limits.

Science of active galactic nuclei with the GTC and CanariCam

Science.gov (United States)

Levenson, Nancy A.; Packham, Christopher C.; Alonso-Herrero, Almudena; Aretxaga, Itziar; Colina, Luis; Díaz-Santos, Tanio; Elitzur, Moshe; Mason, Rachel E.; Perlman, Eric S.; Radomski, James T.; Roche, Patrick F.; Rodríguez Espinosa, José Miguel; Young, Stuart; Telesco, Charles M.

2008-07-01

CanariCam is the facility mid-infrared (MIR) instrument for the Gran Telescopio Canarias (GTC), a 10.4m telescope at the Observatorio del Roque de los Muchachos on La Palma. One of the science drivers for CanariCam is the study of active galactic nuclei (AGN). We will exploit the instrument's high sensitivity in imaging, spectroscopy, and polarimetry modes to answer fundamental questions of AGN and their host galaxies. Dust in the nucleus of an active galaxy reprocesses the intrinsic radiation of the central engine to emerge in the MIR. Current work demonstrates that the hot dust immediately associated with the AGN, which blocks direct views of the AGN from some lines of sight, is confined to small (parsec) scales. Thus, high spatial resolution is essential to probe the "torus" of unified AGN models separate from the host galaxy. CanariCam provides a 0.08" pixel scale for Nyquist sampling the diffraction-limited point spread function at 8μm, and narrow (0.2") spectroscopy slits (with R=120-1300). New observations with the GTC/CanariCam will provide key constraints on the physical conditions in the clumpy torus, and we will sensitively determine AGN obscuration as a function of nuclear activity. We will therefore address the fueling process and its relationship to the torus, the interaction with the host galaxy, and dust chemistry. These data will be essential preparation for the next generation of telescopes that will observe the distant universe directly to explore galaxy and black hole formation and evolution, and the GTC/CanariCam system uniquely provides multiple modes to probe AGN.

New Content Addressable Memory (CAM) Technologies for Big Data and Intelligent Electronics Enabled by Magneto-Electric Ternary CAM

Science.gov (United States)

2017-12-11

AFRL-RY-WP-TR-2017-0198 NEW CONTENT ADDRESSABLE MEMORY (CAM) TECHNOLOGIES FOR BIG DATA AND INTELLIGENT ELECTRONICS ENABLED BY MAGNETO-ELECTRIC...MEMORY (CAM) TECHNOLOGIES FOR BIG DATA AND INTELLIGENT ELECTRONICS ENABLED BY MAGNETO-ELECTRIC TERNARY CAM 5a. CONTRACT NUMBER FA8650-16-1-7655 5b... electronic applications, such as internet of things, big data, wireless sensors, and mobile devices, have begun to focus on the importance of energy

Immunomodulation of Autoimmune Arthritis by Herbal CAM

Directory of Open Access Journals (Sweden)

Shivaprasad H. Venkatesha

2011-01-01

Full Text Available Rheumatoid arthritis (RA is a debilitating autoimmune disease of global prevalence. The disease is characterized by synovial inflammation leading to cartilage and bone damage. Most of the conventional drugs used for the treatment of RA have severe adverse reactions and are quite expensive. Over the years, increasing proportion of patients with RA and other immune disorders are resorting to complementary and alternative medicine (CAM for their health needs. Natural plant products comprise one of the most popular CAM for inflammatory and immune disorders. These herbal CAM belong to diverse traditional systems of medicine, including traditional Chinese medicine, Kampo, and Ayurvedic medicine. In this paper, we have outlined the major immunological pathways involved in the induction and regulation of autoimmune arthritis and described various herbal CAM that can effectively modulate these immune pathways. Most of the information about the mechanisms of action of herbal products in the experimental models of RA is relevant to arthritis patients as well. The study of immunological pathways coupled with the emerging application of genomics and proteomics in CAM research is likely to provide novel insights into the mechanisms of action of different CAM modalities.

Complementary and alternative medicine (CAM providers’ views of chronic low back pain patients’ expectations of CAM therapies: a qualitative study

Directory of Open Access Journals (Sweden)

Schafer Lisa M

2012-11-01

Full Text Available Abstract Background Some researchers think that patients with higher expectations for CAM therapies experience better outcomes and that enthusiastic providers can enhance treatment outcomes. This is in contrast to evidence suggesting conventional medical providers often reorient patient expectations to better match what providers believe to be realistic. However, there is a paucity of research on CAM providers’ views of their patients’ expectations regarding CAM therapy and the role of these expectations in patient outcomes. Methods To better understand how CAM providers view and respond to their patients’ expectations of a particular therapy, we conducted 32 semi-structured, qualitative interviews with acupuncturists, chiropractors, massage therapists and yoga instructors identified through convenience sampling. Interviews were recorded, transcribed and analyzed thematically using Atlas ti version 6.1. Results CAM providers reported that they attempt to ensure that their patients’ expectations are realistic. Providers indicated they manage their patients’ expectations in a number of domains— roles and responsibilities of providers and patients, treatment outcomes, timeframe for improvement, and treatment experience. Providers reported that patients’ expectations change over time and that they need to continually manage these expectations to enhance patient engagement and satisfaction with treatment. Conclusions Providers of four types of CAM therapies viewed patients’ expectations as an important component of their experiences with CAM therapy and indicated that they try to align patient expectations with reality. These findings suggest that CAM providers are similar in this respect to conventional medical providers.

Complementary and alternative medicine (CAM) providers' views of chronic low back pain patients' expectations of CAM therapies: a qualitative study.

Science.gov (United States)

Schafer, Lisa M; Hsu, Clarissa; Eaves, Emery Rose; Ritenbaugh, Cheryl; Turner, Judith; Cherkin, Daniel C; Sims, Colette; Sherman, Karen J

2012-11-27

Some researchers think that patients with higher expectations for CAM therapies experience better outcomes and that enthusiastic providers can enhance treatment outcomes. This is in contrast to evidence suggesting conventional medical providers often reorient patient expectations to better match what providers believe to be realistic. However, there is a paucity of research on CAM providers' views of their patients' expectations regarding CAM therapy and the role of these expectations in patient outcomes. To better understand how CAM providers view and respond to their patients' expectations of a particular therapy, we conducted 32 semi-structured, qualitative interviews with acupuncturists, chiropractors, massage therapists and yoga instructors identified through convenience sampling. Interviews were recorded, transcribed and analyzed thematically using Atlas ti version 6.1. CAM providers reported that they attempt to ensure that their patients' expectations are realistic. Providers indicated they manage their patients' expectations in a number of domains- roles and responsibilities of providers and patients, treatment outcomes, timeframe for improvement, and treatment experience. Providers reported that patients' expectations change over time and that they need to continually manage these expectations to enhance patient engagement and satisfaction with treatment. Providers of four types of CAM therapies viewed patients' expectations as an important component of their experiences with CAM therapy and indicated that they try to align patient expectations with reality. These findings suggest that CAM providers are similar in this respect to conventional medical providers.

Knowledge and training needs among Danish nurses about CAM

DEFF Research Database (Denmark)

Lunde, Anita

2010-01-01

to explore nurses’ knowledge about CAM and their needs for training. Methods: Similar to international investigations a Danish “CAM-knowledge” questionnaire was developed that included multiple choice, yes/no and 5 points scale answers. Validity was established through initial pilot testing. Contacts...... to a randomized sample of 2500 nurses were established through the Danish Nurses Foundation. The questionnaires were mailed by post with the possibility of anonymous return. The data material was analyzed using non-parametic methods. Results: The response rate was 67 % and 1458 completed questionnaires were...... of CAM also tend to have a theoretical background of CAM. Around 75 % of the nurses agree or partly agree that it is important for nurses to receive education about CAM and that nurses have knowledge about CAM that enables them to advise patients. Training needs concerning CAM were indicated by 52...

Machinability of CAD-CAM materials.

Science.gov (United States)

Chavali, Ramakiran; Nejat, Amir H; Lawson, Nathaniel C

2017-08-01

Although new materials are available for computer-aided design and computer-aided manufacturing (CAD-CAM) fabrication, limited information is available regarding their machinability. The depth of penetration of a milling tool into a material during a timed milling cycle may indicate its machinability. The purpose of this in vitro study was to compare the tool penetration rate for 2 polymer-containing CAD-CAM materials (Lava Ultimate and Enamic) and 2 ceramic-based CAD-CAM materials (e.max CAD and Celtra Duo). The materials were sectioned into 4-mm-thick specimens (n=5/material) and polished with 320-grit SiC paper. Each specimen was loaded into a custom milling apparatus. The apparatus pushed the specimens against a milling tool (E4D Tapered 2016000) rotating at 40 000 RPM with a constant force of 0.98 N. After a 6-minute timed milling cycle, the length of each milling cut was measured with image analysis software under a digital light microscope. Representative specimens and milling tools were examined with scanning electron microscopy (SEM) and energy dispersive x-ray spectroscopy. The penetration rate of Lava Ultimate (3.21 ±0.46 mm/min) and Enamic (2.53 ±0.57 mm/min) was significantly greater than that of e.max CAD (1.12 ±0.32 mm/min) or Celtra Duo (0.80 ±0.21 mm/min) materials. SEM observations showed little tool damage, regardless of material type. Residual material was found on the tools used with polymer-containing materials, and wear of the embedding medium was seen on the tools used with the ceramic-based materials. Edge chipping was noted on cuts made in the ceramic-based materials. Lava Ultimate and Enamic have greater machinability and less edge chipping than e.max CAD and Celtra Duo. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

[Intraoperative augmented reality visualization. Current state of development and initial experiences with the CamC].

Science.gov (United States)

Weidert, S; Wang, L; von der Heide, A; Navab, N; Euler, E

2012-03-01

The intraoperative application of augmented reality (AR) has so far mainly taken place in the field of endoscopy. Here, the camera image of the endoscope was augmented by computer graphics derived mostly from preoperative imaging. Due to the complex setup and operation of the devices, they have not yet become part of routine clinical practice. The Camera Augmented Mobile C-arm (CamC) that extends a classic C-arm by a video camera and mirror construction is characterized by its uncomplicated handling. It combines its video live stream geometrically correct with the acquired X-ray. The clinical application of the device in 43 cases showed the strengths of the device in positioning for X-ray acquisition, incision placement, K-wire placement, and instrument guidance. With its new function and the easy integration into the OR workflow of any procedure that requires X-ray imaging, the CamC has the potential to become the first widely used AR technology for orthopedic and trauma surgery.

CLASH: COMPLETE LENSING ANALYSIS OF THE LARGEST COSMIC LENS MACS J0717.5+3745 AND SURROUNDING STRUCTURES

International Nuclear Information System (INIS)

Medezinski, Elinor; Lemze, Doron; Ford, Holland; Umetsu, Keiichi; Nonino, Mario; Merten, Julian; Mroczkowski, Tony; Zitrin, Adi; Broadhurst, Tom; Donahue, Megan; Sayers, Jack; Czakon, Nicole; Waizmann, Jean-Claude; Meneghetti, Massimo; Koekemoer, Anton; Coe, Dan; Postman, Marc; Molino, Alberto; Melchior, Peter; Grillo, Claudio

2013-01-01

The galaxy cluster MACS J0717.5+3745 (z = 0.55) is the largest known cosmic lens, with complex internal structures seen in deep X-ray, Sunyaev-Zel'dovich effect, and dynamical observations. We perform a combined weak- and strong-lensing analysis with wide-field BVR c i'z' Subaru/Suprime-Cam observations and 16-band Hubble Space Telescope observations taken as part of the Cluster Lensing And Supernova survey with Hubble. We find consistent weak distortion and magnification measurements of background galaxies and combine these signals to construct an optimally estimated radial mass profile of the cluster and its surrounding large-scale structure out to 5 Mpc h –1 . We find consistency between strong-lensing and weak-lensing in the region where these independent data overlap, –1 . The two-dimensional weak-lensing map reveals a clear filamentary structure traced by distinct mass halos. We model the lensing shear field with nine halos, including the main cluster, corresponding to mass peaks detected above 2.5σ κ . The total mass of the cluster as determined by the different methods is M vir ≈ (2.8 ± 0.4) × 10 15 M ☉ . Although this is the most massive cluster known at z > 0.5, in terms of extreme value statistics, we conclude that the mass of MACS J0717.5+3745 by itself is not in serious tension with ΛCDM, representing only a ∼2σ departure above the maximum simulated halo mass at this redshift

CLASH: COMPLETE LENSING ANALYSIS OF THE LARGEST COSMIC LENS MACS J0717.5+3745 AND SURROUNDING STRUCTURES

Energy Technology Data Exchange (ETDEWEB)

Medezinski, Elinor; Lemze, Doron; Ford, Holland [Department of Physics and Astronomy, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States); Umetsu, Keiichi [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Nonino, Mario [INAF/Osservatorio Astronomico di Trieste, via G.B. Tiepolo 11, I-34143 Trieste (Italy); Merten, Julian; Mroczkowski, Tony [Jet Propulsion Laboratory, California Institute of Technology, MS 169-327, Pasadena, CA 91109 (United States); Zitrin, Adi [Institut für Theoretische Astrophysik, Universität Heidelberg, Zentrum für Astronomie, Philosophenweg 12, D-69120 Heidelberg (Germany); Broadhurst, Tom [Department of Theoretical Physics and History of Science, University of the Basque Country UPV/EHU, P.O. Box 644, E-48080 Bilbao (Spain); Donahue, Megan [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Sayers, Jack; Czakon, Nicole [Division of Physics, Math, and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Waizmann, Jean-Claude; Meneghetti, Massimo [Dipartimento di Astronomia, Universit' a di Bologna, via Ranzani 1, I-40127 Bologna (Italy); Koekemoer, Anton; Coe, Dan; Postman, Marc [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21208 (United States); Molino, Alberto [Instituto de Astrofísica de Andalucía (CSIC), E-18080 Granada (Spain); Melchior, Peter [Center for Cosmology and Astro-Particle Physics and Department of Physics, The Ohio State University, Columbus, OH 43210 (United States); Grillo, Claudio, E-mail: elinor@pha.jhu.edu [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Mariesvej 30, DK-2100 Copenhagen (Denmark); and others

2013-11-01

The galaxy cluster MACS J0717.5+3745 (z = 0.55) is the largest known cosmic lens, with complex internal structures seen in deep X-ray, Sunyaev-Zel'dovich effect, and dynamical observations. We perform a combined weak- and strong-lensing analysis with wide-field BVR{sub c} i'z' Subaru/Suprime-Cam observations and 16-band Hubble Space Telescope observations taken as part of the Cluster Lensing And Supernova survey with Hubble. We find consistent weak distortion and magnification measurements of background galaxies and combine these signals to construct an optimally estimated radial mass profile of the cluster and its surrounding large-scale structure out to 5 Mpc h {sup –1}. We find consistency between strong-lensing and weak-lensing in the region where these independent data overlap, <500 kpc h {sup –1}. The two-dimensional weak-lensing map reveals a clear filamentary structure traced by distinct mass halos. We model the lensing shear field with nine halos, including the main cluster, corresponding to mass peaks detected above 2.5σ{sub κ}. The total mass of the cluster as determined by the different methods is M{sub vir} ≈ (2.8 ± 0.4) × 10{sup 15} M{sub ☉}. Although this is the most massive cluster known at z > 0.5, in terms of extreme value statistics, we conclude that the mass of MACS J0717.5+3745 by itself is not in serious tension with ΛCDM, representing only a ∼2σ departure above the maximum simulated halo mass at this redshift.

Treatment Preferences for CAM in Children with Chronic Pain

Directory of Open Access Journals (Sweden)

Jennie C. I. Tsao

2007-01-01

Full Text Available CAM therapies have become increasingly popular in pediatric populations. Yet, little is known about children's preferences for CAM. This study examined treatment preferences in chronic pediatric pain patients offered a choice of CAM therapies for their pain. Participants were 129 children (94 girls (mean age = 14.5 years ± 2.4; range = 8–18 years presenting at a multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Bivariate and multivariate analyses were used to examine the relationships between CAM treatment preferences and patient's sociodemographic and clinical characteristics, as well as their self-reported level of functioning. Over 60% of patients elected to try at least one CAM approach for pain. The most popular CAM therapies were biofeedback, yoga and hypnosis; the least popular were art therapy and energy healing, with craniosacral, acupuncture and massage being intermediate. Patients with a diagnosis of fibromyalgia (80% were the most likely to try CAM versus those with other pain diagnoses. In multivariate analyses, pain duration emerged as a significant predictor of CAM preferences. For mind-based approaches (i.e. hypnosis, biofeedback and art therapy, pain duration and limitations in family activities were both significant predictors. When given a choice of CAM therapies, this sample of children with chronic pain, irrespective of pain diagnosis, preferred non-invasive approaches that enhanced relaxation and increased somatic control. Longer duration of pain and greater impairment in functioning, particularly during family activities increased the likelihood that such patients agreed to engage in CAM treatments, especially those that were categorized as mind-based modalities.

Treatment Preferences for CAM in children with chronic pain.

Science.gov (United States)

Tsao, Jennie C I; Meldrum, Marcia; Kim, Su C; Jacob, Margaret C; Zeltzer, Lonnie K

2007-09-01

CAM therapies have become increasingly popular in pediatric populations. Yet, little is known about children's preferences for CAM. This study examined treatment preferences in chronic pediatric pain patients offered a choice of CAM therapies for their pain. Participants were 129 children (94 girls) (mean age = 14.5 years +/- 2.4; range = 8-18 years) presenting at a multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Bivariate and multivariate analyses were used to examine the relationships between CAM treatment preferences and patient's sociodemographic and clinical characteristics, as well as their self-reported level of functioning. Over 60% of patients elected to try at least one CAM approach for pain. The most popular CAM therapies were biofeedback, yoga and hypnosis; the least popular were art therapy and energy healing, with craniosacral, acupuncture and massage being intermediate. Patients with a diagnosis of fibromyalgia (80%) were the most likely to try CAM versus those with other pain diagnoses. In multivariate analyses, pain duration emerged as a significant predictor of CAM preferences. For mind-based approaches (i.e. hypnosis, biofeedback and art therapy), pain duration and limitations in family activities were both significant predictors. When given a choice of CAM therapies, this sample of children with chronic pain, irrespective of pain diagnosis, preferred non-invasive approaches that enhanced relaxation and increased somatic control. Longer duration of pain and greater impairment in functioning, particularly during family activities increased the likelihood that such patients agreed to engage in CAM treatments, especially those that were categorized as mind-based modalities.

CAMS: OLAPing Multidimensional Data Streams Efficiently

Science.gov (United States)

Cuzzocrea, Alfredo

In the context of data stream research, taming the multidimensionality of real-life data streams in order to efficiently support OLAP analysis/mining tasks is a critical challenge. Inspired by this fundamental motivation, in this paper we introduce CAMS (C ube-based A cquisition model for M ultidimensional S treams), a model for efficiently OLAPing multidimensional data streams. CAMS combines a set of data stream processing methodologies, namely (i) the OLAP dimension flattening process, which allows us to obtain dimensionality reduction of multidimensional data streams, and (ii) the OLAP stream aggregation scheme, which aggregates data stream readings according to an OLAP-hierarchy-based membership approach. We complete our analytical contribution by means of experimental assessment and analysis of both the efficiency and the scalability of OLAPing capabilities of CAMS on synthetic multidimensional data streams. Both analytical and experimental results clearly connote CAMS as an enabling component for next-generation Data Stream Management Systems.

Marginal Fit Comparison of CAD/CAM Crowns Milled from Two Different Materials.

Science.gov (United States)

Azarbal, Atousa; Azarbal, Mohsen; Engelmeier, Robert L; Kunkel, Thomas C

2017-11-16

To evaluate the marginal fit of CAD/CAM copings milled from hybrid ceramic (Vita Enamic) blocks and lithium disilicate (IPS e.max CAD) blocks, and to evaluate the effect of crystallization firing on the marginal fit of lithium disilicate copings. A standardized metal die with a 1-mm-wide shoulder finish line was imaged using the CEREC AC Bluecam. The coping was designed using CEREC 3 software. The design was used to fabricate 15 lithium disilicate and 15 hybrid ceramic copings. Design and milling were accomplished by one operator. The copings were seated on the metal die using a pressure clamp with a uniform pressure of 5.5 lbs. A Macroview Microscope (14×) was used for direct viewing of the marginal gap. Four areas were imaged on each coping (buccal, distal, lingual, mesial). Image analysis software was used to measure the marginal gaps in μm at 15 randomly selected points on each of the four surfaces. A total of 60 measurements were made per specimen. For lithium disilicate copings the measurements for marginal gap were made before and after crystallization firing. Data were analyzed using paired t-test and Kruskal-Wallis test. The overall mean difference in marginal gap between the hybrid ceramic and crystallized lithium disilicate copings was statistically significant (p marginal gaps were measured for crystallized lithium disilicate copings. The overall mean difference in marginal gap before and after firing (precrystallized and crystallized lithium disilicate copings) showed an average of 62 μm increase in marginal gap after firing. This difference was also significant (p marginal gap discrepancy when comparing hybrid ceramic and lithium disilicate CAD/CAM crowns. Also crystallization firing can result in a significant increase in the marginal gap of lithium disilicate CAD/CAM crowns. © 2017 by the American College of Prosthodontists.

MULTI-EPOCH IMAGING POLARIMETRY OF THE SiO MASERS IN THE EXTENDED ATMOSPHERE OF THE MIRA VARIABLE TX CAM

International Nuclear Information System (INIS)

Kemball, Athol J.; Diamond, Philip J.; Gonidakis, Ioannis; Mitra, Modhurita; Yim, Kijeong; Pan, K.-C.; Chiang, H.-F.

2009-01-01

We present a time series of synoptic images of the linearly polarized v = 1, J = 1-0 SiO maser emission toward the Mira variable, TX Cam. These data comprise 43 individual epochs at an approximate biweekly sampling over an optical pulsation phase range of φ = 0.68 to φ = 1.82. The images have an angular resolution of ∼500 μas and were obtained using the Very Long Baseline Array (VLBA), operating in the 43 GHz band in spectral-line, polarization mode. We have previously published the total intensity time series for this pulsation phase range; this paper serves to present the linearly polarized image sequence and an associated animation representing the evolution of the linear polarization morphology over time. We find a predominantly tangential polarization morphology, a high degree of persistence in linear polarization properties over individual component lifetimes, and stronger linear polarization in the inner projected shell than at larger projected shell radii. We present an initial polarization proper motion analysis examining the possible dynamical influence of magnetic fields in component motions in the extended atmospheres of late-type, evolved stars.

Automated analysis of angle closure from anterior chamber angle images.

Science.gov (United States)

Baskaran, Mani; Cheng, Jun; Perera, Shamira A; Tun, Tin A; Liu, Jiang; Aung, Tin

2014-10-21

To evaluate a novel software capable of automatically grading angle closure on EyeCam angle images in comparison with manual grading of images, with gonioscopy as the reference standard. In this hospital-based, prospective study, subjects underwent gonioscopy by a single observer, and EyeCam imaging by a different operator. The anterior chamber angle in a quadrant was classified as closed if the posterior trabecular meshwork could not be seen. An eye was classified as having angle closure if there were two or more quadrants of closure. Automated grading of the angle images was performed using customized software. Agreement between the methods was ascertained by κ statistic and comparison of area under receiver operating characteristic curves (AUC). One hundred forty subjects (140 eyes) were included, most of whom were Chinese (102/140, 72.9%) and women (72/140, 51.5%). Angle closure was detected in 61 eyes (43.6%) with gonioscopy in comparison with 59 eyes (42.1%, P = 0.73) using manual grading, and 67 eyes (47.9%, P = 0.24) with automated grading of EyeCam images. The agreement for angle closure diagnosis between gonioscopy and both manual (κ = 0.88; 95% confidence interval [CI), 0.81-0.96) and automated grading of EyeCam images was good (κ = 0.74; 95% CI, 0.63-0.85). The AUC for detecting eyes with gonioscopic angle closure was comparable for manual and automated grading (AUC 0.974 vs. 0.954, P = 0.31) of EyeCam images. Customized software for automated grading of EyeCam angle images was found to have good agreement with gonioscopy. Human observation of the EyeCam images may still be needed to avoid gross misclassification, especially in eyes with extensive angle closure. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

Chiropractic and CAM utilization: a descriptive review.

Science.gov (United States)

Lawrence, Dana J; Meeker, William C

2007-01-22

To conduct a descriptive review of the scientific literature examining use rates of modalities and procedures used by CAM clinicians to manage chronic LBP and other conditions A literature of PubMed and MANTIS was performed using the key terms Chiropractic; Low Back Pain; Utilization Rate; Use Rate; Complementary and Alternative Medicine; and Health Services in various combinations. A total of 137 papers were selected, based upon including information about chiropractic utilization, CAM utilization and low back pain and other conditions. Information was extracted from each paper addressing use of chiropractic and CAM, and is summarized in tabular form. Thematic analysis of the paper topics indicated that there were 5 functional areas covered by the literature: back pain papers, general chiropractic papers, insurance-related papers, general CAM-related papers; and worker's compensation papers. Studies looking at chiropractic utilization demonstrate that the rates vary, but generally fall into a range from around 6% to 12% of the population, most of whom seek chiropractic care for low back pain and not for organic disease or visceral dysfunction. CAM is itself used by people suffering from a variety of conditions, though it is often used not as a primary intervention, but rather as an additional form of care. CAM and chiropractic often offer lower costs for comparable results compared to conventional medicine.

3D FaceCam: a fast and accurate 3D facial imaging device for biometrics applications

Science.gov (United States)

Geng, Jason; Zhuang, Ping; May, Patrick; Yi, Steven; Tunnell, David

2004-08-01

Human faces are fundamentally three-dimensional (3D) objects, and each face has its unique 3D geometric profile. The 3D geometric features of a human face can be used, together with its 2D texture, for rapid and accurate face recognition purposes. Due to the lack of low-cost and robust 3D sensors and effective 3D facial recognition (FR) algorithms, almost all existing FR systems use 2D face images. Genex has developed 3D solutions that overcome the inherent problems in 2D while also addressing limitations in other 3D alternatives. One important aspect of our solution is a unique 3D camera (the 3D FaceCam) that combines multiple imaging sensors within a single compact device to provide instantaneous, ear-to-ear coverage of a human face. This 3D camera uses three high-resolution CCD sensors and a color encoded pattern projection system. The RGB color information from each pixel is used to compute the range data and generate an accurate 3D surface map. The imaging system uses no moving parts and combines multiple 3D views to provide detailed and complete 3D coverage of the entire face. Images are captured within a fraction of a second and full-frame 3D data is produced within a few seconds. This described method provides much better data coverage and accuracy in feature areas with sharp features or details (such as the nose and eyes). Using this 3D data, we have been able to demonstrate that a 3D approach can significantly improve the performance of facial recognition. We have conducted tests in which we have varied the lighting conditions and angle of image acquisition in the "field." These tests have shown that the matching results are significantly improved when enrolling a 3D image rather than a single 2D image. With its 3D solutions, Genex is working toward unlocking the promise of powerful 3D FR and transferring FR from a lab technology into a real-world biometric solution.

CAD/CAM produces dentures with improved fit.

Science.gov (United States)

Steinmassl, Otto; Dumfahrt, Herbert; Grunert, Ingrid; Steinmassl, Patricia-Anca

2018-02-22

Resin polymerisation shrinkage reduces the congruence of the denture base with denture-bearing tissues and thereby decreases the retention of conventionally fabricated dentures. CAD/CAM denture manufacturing is a subtractive process, and polymerisation shrinkage is not an issue anymore. Therefore, CAD/CAM dentures are assumed to show a higher denture base congruence than conventionally fabricated dentures. It has been the aim of this study to test this hypothesis. CAD/CAM dentures provided by four different manufacturers (AvaDent, Merz Dental, Whole You, Wieland/Ivoclar) were generated from ten different master casts. Ten conventional dentures (pack and press, long-term heat polymerisation) made from the same master casts served as control group. The master casts and all denture bases were scanned and matched digitally. The absolute incongruences were measured using a 2-mm mesh. Conventionally fabricated dentures showed a mean deviation of 0.105 mm, SD = 0.019 from the master cast. All CAD/CAM dentures showed lower mean incongruences. From all CAD/CAM dentures, AvaDent Digital Dentures showed the highest congruence with the master cast surface with a mean deviation of 0.058 mm, SD = 0.005. Wieland Digital Dentures showed a mean deviation of 0.068 mm, SD = 0.005, Whole You Nexteeth prostheses showed a mean deviation of 0.074 mm, SD = 0.011 and Baltic Denture System prostheses showed a mean deviation of 0.086 mm, SD = 0.012. CAD/CAM produces dentures with better fit than conventional dentures. The present study explains the clinically observed enhanced retention and lower traumatic ulcer-frequency in CAD/CAM dentures.

Engine testing of ceramic cam-roller followers

Energy Technology Data Exchange (ETDEWEB)

Kalish, Y. (Detroit Diesel Corp., MI (United States))

1992-04-01

For several years, DDC has been developing monolithic ceramic heat engine components. One of the components, developed for an application in our state-of-the-art on-highway, heavy-duty diesel engine, the Series 60, is a silicon nitride cam-roller follower. Prior to starting this program, each valve train component in the Series 60 was considered for conversion to a ceramic material. Many advantages and disadvantages (benefits and risks) were considered. From this effort, one component was selected, the cam-roller follower. Using a system design approach, a ceramic cam-roller follower offered functional improvement at a reasonable cost. The purpose of the project was to inspect and test 100 domestically produced silicon nitride cam-roller followers built to the requirements of the DDC series 60 engine.

Availability Analysis of the Ventilation Stack CAM Interlock System

International Nuclear Information System (INIS)

YOUNG, J.

2000-01-01

Ventilation Stack Continuous Air Monitor (CAM) Interlock System failure modes, failure frequencies and system availability have been evaluated for the RPP. The evaluation concludes that CAM availability is as high as assumed in the safety analysis and that the current routine system surveillance is adequate to maintain this availability. Further, requiring an alarm to actuate upon CAM failure is not necessary to maintain the availability credited in the safety analysis, nor is such an arrangement predicted to significantly improve system availability. However, if CAM failures were only detected by the 92-day functional tests required in the Authorization Basis (AB), CAM availability would be much less than that credited in the safety analysis. Therefore it is recommended that the current surveillance practice of daily simple system checks, 30-day source checks and 92-day functional tests be continued in order to maintain CAM availability

Calibration of the MSL/ChemCam/LIBS Remote Sensing Composition Instrument

Science.gov (United States)

Wiens, R. C.; Maurice S.; Bender, S.; Barraclough, B. L.; Cousin, A.; Forni, O.; Ollila, A.; Newsom, H.; Vaniman, D.; Clegg, S.;

Laia de Camões — O épico

Directory of Open Access Journals (Sweden)

Lygia Alvares Correa

1951-06-01

Full Text Available CIDADE ('liernatii. Laia de Camões — O épico, Revista da Faculdade  de Letras. Tomo XVI. 2.°' série. ns. I e 2. Universidade de Lisboa  1950. (Primeiro Parágrafo do Artigo Este segundo volume que a respeito de Camões escreve o Prof. Cidade surge 14 anos após, "Luiz de Camões".

Chiropractic and CAM Utilization: A Descriptive Review

Directory of Open Access Journals (Sweden)

Meeker William C

2007-01-01

Full Text Available Abstract Objective To conduct a descriptive review of the scientific literature examining use rates of modalities and procedures used by CAM clinicians to manage chronic LBP and other conditions Data Sources A literature of PubMed and MANTIS was performed using the key terms Chiropractic; Low Back Pain; Utilization Rate; Use Rate; Complementary and Alternative Medicine; and Health Services in various combinations. Data Selection A total of 137 papers were selected, based upon including information about chiropractic utilization, CAM utilization and low back pain and other conditions. Data Synthesis Information was extracted from each paper addressing use of chiropractic and CAM, and is summarized in tabular form. Results Thematic analysis of the paper topics indicated that there were 5 functional areas covered by the literature: back pain papers, general chiropractic papers, insurance-related papers, general CAM-related papers; and worker's compensation papers. Conclusion Studies looking at chiropractic utilization demonstrate that the rates vary, but generally fall into a range from around 6% to 12% of the population, most of whom seek chiropractic care for low back pain and not for organic disease or visceral dysfunction. CAM is itself used by people suffering from a variety of conditions, though it is often used not as a primary intervention, but rather as an additional form of care. CAM and chiropractic often offer lower costs for comparable results compared to conventional medicine.

Genomic analyses of the CAM plant pineapple.

Science.gov (United States)

Zhang, Jisen; Liu, Juan; Ming, Ray

2014-07-01

The innovation of crassulacean acid metabolism (CAM) photosynthesis in arid and/or low CO2 conditions is a remarkable case of adaptation in flowering plants. As the most important crop that utilizes CAM photosynthesis, the genetic and genomic resources of pineapple have been developed over many years. Genetic diversity studies using various types of DNA markers led to the reclassification of the two genera Ananas and Pseudananas and nine species into one genus Ananas and two species, A. comosus and A. macrodontes with five botanical varieties in A. comosus. Five genetic maps have been constructed using F1 or F2 populations, and high-density genetic maps generated by genotype sequencing are essential resources for sequencing and assembling the pineapple genome and for marker-assisted selection. There are abundant expression sequence tag resources but limited genomic sequences in pineapple. Genes involved in the CAM pathway has been analysed in several CAM plants but only a few of them are from pineapple. A reference genome of pineapple is being generated and will accelerate genetic and genomic research in this major CAM crop. This reference genome of pineapple provides the foundation for studying the origin and regulatory mechanism of CAM photosynthesis, and the opportunity to evaluate the classification of Ananas species and botanical cultivars. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

A CNES remote operations center for the MSL ChemCam instrument

Energy Technology Data Exchange (ETDEWEB)

Wiens, Roger C [Los Alamos National Laboratory; Lafaille, Vivian [CNES; Lorgny, Eric [CNES; Baroukh, Julien [CNES; Gaboriaud, Alain [CNES; Saccoccio, Muriel [CNES; Perez, Rene [CNES; Gasnault, Olivier [CNRS/CESR; Maurice, Sylvestre [CNRS/CESR; Blaney, Diana [JPL

2010-01-01

For the first time, a CNES remote operations center in Toulouse will be involved in the tactical operations of a Martian rover in order to operate the ChemCam science instrument in the framework of the NASA MSL (Mars Science Laboratory) mission in 2012. CNES/CESR and LANL have developed and delivered to JPL the ChemCam (Chemistry Camera) instrument located on the top of mast and in the body of the rover. This instrument incorporates a Laser-Induced Breakdown Spectrometer (LIBS) and a Remote Micro-Imager (RMI) for determining elemental compositions of rock targets or soil samples at remote distances from the rover (2-7 m). An agreement has been achieved for operating ChemCam, alternatively, from Toulouse (FR) and Los Alamos (NM, USA), through the JPL ground data system in Pasadena (CA, USA) for a complete Martian year (2 years on Earth). After a brief overview of the MSL mission, this paper presents the instrument, the mission operational system and JPL organization requirements for the scientific investigators (PI and Co-Is). This paper emphasizes innovations applied on the ground segment components and on the operational approach to satisfy the requirements and constraints due to these shared and distributed operations over the world.

Mapping compound cosmic telescopes containing multiple projected cluster-scale halos

Energy Technology Data Exchange (ETDEWEB)

Ammons, S. Mark [Lawrence Livermore National Laboratory, Physics Division L-210, 7000 East Ave., Livermore, CA 94550 (United States); Wong, Kenneth C. [EACOA Fellow, Institute of Astronomy and Astrophysics, Academia Sinica (ASIAA), Taipei 10641, Taiwan (China); Zabludoff, Ann I. [Steward Observatory, University of Arizona, 933 Cherry Ave., Tucson, AZ 85721 (United States); Keeton, Charles R., E-mail: ammons1@llnl.gov, E-mail: kwong@as.arizona.edu, E-mail: aiz@email.arizona.edu, E-mail: keeton@physics.rutgers.edu [Department of Physics and Astronomy, Rutgers University, 136 Frelinghuysen Road, Piscataway, NJ 08854 (United States)

2014-01-20

Lines of sight with multiple projected cluster-scale gravitational lenses have high total masses and complex lens plane interactions that can boost the area of magnification, or étendue, making detection of faint background sources more likely than elsewhere. To identify these new 'compound' cosmic telescopes, we have found directions in the sky with the highest integrated mass densities, as traced by the projected concentrations of luminous red galaxies (LRGs). We use new galaxy spectroscopy to derive preliminary magnification maps for two such lines of sight with total mass exceeding ∼3 × 10{sup 15} M {sub ☉}. From 1151 MMT Hectospec spectra of galaxies down to i {sub AB} = 21.2, we identify two to three group- and cluster-scale halos in each beam. These are well traced by LRGs. The majority of the mass in beam J085007.6+360428 (0850) is contributed by Zwicky 1953, a massive cluster at z = 0.3774, whereas beam J130657.5+463219 (1306) is composed of three halos with virial masses of 6 × 10{sup 14}-2 × 10{sup 15} M {sub ☉}, one of which is A1682. The magnification maps derived from our mass models based on spectroscopy and Sloan Digital Sky Survey photometry alone display substantial étendue: the 68% confidence bands on the lens plane area with magnification exceeding 10 for a source plane of z{sub s} = 10 are [1.2, 3.8] arcmin{sup 2} for 0850 and [2.3, 6.7] arcmin{sup 2} for 1306. In deep Subaru Suprime-Cam imaging of beam 0850, we serendipitously discover a candidate multiply imaged V-dropout source at z {sub phot} = 5.03. The location of the candidate multiply imaged arcs is consistent with the critical curves for a source plane of z = 5.03 predicted by our mass model. Incorporating the position of the candidate multiply imaged galaxy as a constraint on the critical curve location in 0850 narrows the 68% confidence band on the lens plane area with μ > 10 and z{sub s} = 10 to [1.8, 4.2] arcmin{sup 2}, an étendue range comparable to that of

Camshaft bearing arrangement for overhead cam engine

Energy Technology Data Exchange (ETDEWEB)

Yoshikawa, M.

1985-01-01

In an assembly for an internal combustion engine comprising a cylinder block, a cylinder head detachably affixed to the cylinder block by a plurality of threaded fastening means, a plurality of poppet valves supported for reciprocation in the cylinder head and a camshaft for operating the poppet valves, the improvement is described comprising a cam carrier detachably affixed to the cylinder head and overlying the threaded fastening means, and a bearing cap affixed to the cam carrier. The cam carrier and the bearing cap have bearing surfaces for journaling the camshaft.

The ChemCam Instrument Suite on the Mars Science Laboratory (MSL) Rover: Body Unit and Combined System Tests

International Nuclear Information System (INIS)

Wiens, Roger C.; Barraclough, Bruce; Barkley, Walter C.; Bender, Steve; Bernardin, John; Bultman, Nathan; Clanton, Robert C.; Clegg, Samuel; Delapp, Dorothea; Dingler, Robert; Enemark, Don; Flores, Mike; Hale, Thomas; Lanza, Nina; Lasue, Jeremie; Latino, Joseph; Little, Cynthia; Morrison, Leland; Nelson, Tony; Romero, Frank; Salazar, Steven; Stiglich, Ralph; Storms, Steven; Trujillo, Tanner; Ulibarri, Mike; Vaniman, David; Whitaker, Robert; Witt, James; Maurice, Sylvestre; Bouye, Marc; Cousin, Agnes; Cros, Alain; D'Uston, Claude; Forni, Olivier; Gasnault, Olivier; Kouach, Driss; Lasue, Jeremie; Pares, Laurent; Poitrasson, Franck; Striebig, Nicolas; Thocaven, Jean-Jacques; Saccoccio, Muriel; Perez, Rene; Bell, James F. III; Hays, Charles; Blaney, Diana; DeFlores, Lauren; Elliott, Tom; Kan, Ed; Limonadi, Daniel; Lindensmith, Chris; Miller, Ed; Reiter, Joseph W.; Roberts, Tom; Simmonds, John J.; Warner, Noah; Blank, Jennifer; Bridges, Nathan; Cais, Phillippe; Clark, Benton; Cremers, David; Dyar, M. Darby; Fabre, Cecile; Herkenhoff, Ken; Kirkland, Laurel; Landis, David; Langevin, Yves; Lanza, Nina; Newsom, Horton; Ollila, Ann; LaRocca, Frank; Ott, Melanie; Mangold, Nicolas; Manhes, Gerard; Mauchien, Patrick; Blank, Jennifer; McKay, Christopher; Mooney, Joe; Provost, Cheryl; Morris, Richard V.; Sautter, Violaine; Sautter, Violaine; Waterbury, Rob; Wong-Swanson, Belinda; Barraclough, Bruce; Bender, Steve; Vaniman, David

2012-01-01

The ChemCam instrument suite on the Mars Science Laboratory (MSL) rover Curiosity provides remote compositional information using the first laser-induced breakdown spectrometer (LIBS) on a planetary mission, and provides sample texture and morphology data using a remote micro-imager (RMI). Overall, ChemCam supports MSL with five capabilities: remote classification of rock and soil characteristics; quantitative elemental compositions including light elements like hydrogen and some elements to which LIBS is uniquely sensitive (e.g., Li, Be, Rb, Sr, Ba); remote removal of surface dust and depth profiling through surface coatings; context imaging; and passive spectroscopy over the 240-905 nm range. ChemCam is built in two sections: The mast unit, consisting of a laser, telescope, RMI, and associated electronics, resides on the rover's mast, and is described in a companion paper. ChemCam's body unit, which is mounted in the body of the rover, comprises an optical de-multiplexer, three spectrometers, detectors, their coolers, and associated electronics and data handling logic. Additional instrument components include a 6 m optical fiber which transfers the LIBS light from the telescope to the body unit, and a set of onboard calibration targets. ChemCam was integrated and tested at Los Alamos National Laboratory where it also underwent LIBS calibration with 69 geological standards prior to integration with the rover. Post-integration testing used coordinated mast and instrument commands, including LIBS line scans on rock targets during system-level thermal-vacuum tests. In this paper we describe the body unit, optical fiber, and calibration targets, and the assembly, testing, and verification of the instrument prior to launch. (authors)

A Novel Radiation Hardened CAM

CERN Document Server

Shojaii, Seyed Ruhollah; The ATLAS collaboration

2018-01-01

This poster describes an innovative Content Addressable Memory cell with radiation hardened (RH-CAM) architecture. The RH-CAM is designed in a commercial 28 nm CMOS technology. The circuit has been simulated in worst-case conditions, and the effects due to single particles are analyzed injecting a fault current into a circuit node. The proposed architecture can perform on-time pattern recognition tasks in harsh environments, such as very front-end electronics in hadron colliders and in space applications.

design analysis of cam-follower system for beat up motion

African Journals Online (AJOL)

User

A cam swing roller-follower mechanism is designed for the beat-up motion of a horizontal narrow loom. The system consists of a radial plate-cam driven by a camshaft keyed to the plate cam. A slay bar which act as the beater is attached to the radial swing roller-follower and assembled on the plate cam. A continuous ...

Cam Drive Step Mechanism of a Quadruped Robot

Directory of Open Access Journals (Sweden)

Qun Sun

2014-01-01

Full Text Available Bionic quadruped robots received considerable worldwide research attention. For a quadruped robot walking with steady paces on a flat terrain, using a cam drive control mechanism instead of servomotors provides theoretical and practical benefits as it reduces the system weight, cost, and control complexities; thus it may be more cost beneficial for some recreational or household applications. This study explores the robot step mechanism including the leg and cam drive control systems based on studying the bone structure and the kinematic step sequences of dog. The design requirements for the cam drive robot legs have been raised, and the mechanical principles of the leg operating mechanism as well as the control parameters have been analyzed. A cam drive control system was constructed using three cams to control each leg. Finally, a four-leg demo robot was manufactured for experiments and it showed stable walking patterns on a flat floor.

Around 1500 near-Earth-asteroid orbits improved via EURONEAR

Science.gov (United States)

Vaduvescu, O.; Hudin, L.; Birlan, M.; Popescu, M.; Tudorica, A.; Toma, R.

2014-07-01

Born in 2006 in Paris, the European Near Earth Asteroids Research project (EURONEAR, euronear.imcce.fr) aims ''to study NEAs and PHAs using existing telescopes available to its network and hopefully in the future some automated dedicated 1--2 m facilities''. Although we believe the first aim is fulfilled, the second was not achieved yet, requiring serious commitment from the European NEA researchers and funding agencies. Mainly using free labor by about 30 students and amateur astronomers (from Romania, Chile, UK, France, etc), the PI backed up by his associates M. Birlan (IMCCE Paris) and J. Licandro (IAC Tenerife) and a few other astronomers of the EURONEAR network having access to a few telescopes are approaching around 1,500 observed NEAs whose orbits were improved based on our astrometric contributions. To achive this milestone, we used two main resources and a total of 15 facilities: i) Observing time obtained at 11 professional 1--4 m class telescopes (Chile, La Palma, France, Germany) plus 3 smaller 30--50 cm educational/public outreach telescopes (Romania and Germany) adding about 1,000 observed NEAs; and ii) astrometry obtained from data mining of 4 major image archives (ESO/MPG WFI, INT WFC, CFHTLS Megacam and Subaru SuprimeCam) adding about 500 NEAs recovered in archival images. Among the highlights, about 100 NEAs, PHAs and VIs were observed, recovered or precovered in archives at their second opposition (up to about 15 years away from discovery) or have their orbital arc much extended, and a few VIs and PHAs were eliminated. Incidentally, about 15,000 positions of almost 2,000 known MBAs were reported (mostly in the INT, ESO/MPG and Blanco large fields). About 40 new (one night) NEO candidates and more than 2,000 (one night) unknown MBAs were reported, including about 150 MBAs credited as EURONEAR discoveries. Based on the INT and Blanco data we derived some statistics about the MBA and NEA population observable with 2m and 4m telescopes, proposing a

Introduction to Analytical Methods for Internal Combustion Engine Cam Mechanisms

CERN Document Server

Williams, J J

2013-01-01

Modern design methods of Automotive Cam Design require the computation of a range of parameters. This book provides a logical sequence of steps for the derivation of the relevant equations from first principles, for the more widely used cam mechanisms. Although originally derived for use in high performance engines, this work is equally applicable to the design of mass produced automotive and other internal combustion engines.   Introduction to Analytical Methods for Internal Combustion Engine Cam Mechanisms provides the equations necessary for the design of cam lift curves with an associated smooth acceleration curve. The equations are derived for the kinematics and kinetics of all the mechanisms considered, together with those for cam curvature and oil entrainment velocity. This permits the cam shape, all loads, and contact stresses to be evaluated, and the relevant tribology to be assessed. The effects of asymmetry on the manufacture of cams for finger follower and offset translating curved followers is ...

Finding the Evidence in CAM: a Student's Perspective

Directory of Open Access Journals (Sweden)

Jeffrey Ghassemi

2005-01-01

Full Text Available This commentary offers a future health care provider's perspective on the role of complementary and alternative medicine (CAM in Western (namely, in US medical education and practice. As a student of both public health and medicine in the United States, Jeffrey Ghassemi is interested in CAM's contribution to improving medical practice and teaching. The commentary highlights the ambiguous definitions of CAM to Westerners despite the rising popularity of and expenditures for alternative modalities of care. It then argues for collaboration between alternative and established medical communities to ascertain the scientific merits of CAM. It concludes by calling for a new medical paradigm that embraces the philosophies of both communities to advance education and patient care.

Use of Complementary and Alternative Medicine (CAM) as Part of the Oncological Treatment: Survey about Patients' Attitude towards CAM in a University-Based Oncology Center in Germany.

Science.gov (United States)

Kessel, Kerstin A; Lettner, Sabrina; Kessel, Carmen; Bier, Henning; Biedermann, Tilo; Friess, Helmut; Herrschbach, Peter; Gschwend, Jürgen E; Meyer, Bernhard; Peschel, Christian; Schmid, Roland; Schwaiger, Markus; Wolff, Klaus-Dietrich; Combs, Stephanie E

2016-01-01

To understand if and which patients would be open-minded to Complementary and Alternative Medicine (CAM) use parallel to their oncological treatment. Moreover, we sought to determine which methods are most accepted and which are the primary motivators to use CAM. We developed and anonymously conducted a questionnaire for patients in the oncology center (TU Munich). Questions focus on different CAM methods, previous experiences, and willingness to apply or use CAM when offered in a university-based setting. A total of 171 of 376 patients (37.4% women, 62.0% men, 0.6% unknown) participated. This corresponds to a return rate of 45%. Median age was 64 years (17-87 years). Of all participants, 15.2% used CAM during their oncological therapy; 32.7% have used it in the past. The majority (81.9%) was not using CAM during therapy; 55.5% have not used CAM in the past respectively. The analysis revealed a significant correlation between education and CAM use during therapy (r = 0.18; p = 0.02), and CAM use in the past (r = 0.17; p = 0.04). Of all patients using CAM during therapy, favored methods were food supplements (42.3%), vitamins/minerals (42.3%), massage (34.6%). Motivations are especially the reduction of side effect and stress, the positive effect of certain CAM-treatments on the immune system and tumor therapy. Results showed no difference between women and men. Most patients not having had any experience with CAM complain about the deficiency of information by their treating oncologist (31.4%) as well as missing treatment possibilities (54.3%). Since many patients believe in study results demonstrating the efficacy of CAM, it stresses our task to develop innovative study protocols to investigate the outcomes of certain CAM on symptom reduction or other endpoints. Thus, prospective trials and innovative evidence-based treatment concepts to include CAM into high-end oncology is what patients demand and what a modern oncology center should offer.

Use of Complementary and Alternative Medicine (CAM as Part of the Oncological Treatment: Survey about Patients' Attitude towards CAM in a University-Based Oncology Center in Germany.

Directory of Open Access Journals (Sweden)

Kerstin A Kessel

Full Text Available To understand if and which patients would be open-minded to Complementary and Alternative Medicine (CAM use parallel to their oncological treatment. Moreover, we sought to determine which methods are most accepted and which are the primary motivators to use CAM.We developed and anonymously conducted a questionnaire for patients in the oncology center (TU Munich. Questions focus on different CAM methods, previous experiences, and willingness to apply or use CAM when offered in a university-based setting.A total of 171 of 376 patients (37.4% women, 62.0% men, 0.6% unknown participated. This corresponds to a return rate of 45%. Median age was 64 years (17-87 years. Of all participants, 15.2% used CAM during their oncological therapy; 32.7% have used it in the past. The majority (81.9% was not using CAM during therapy; 55.5% have not used CAM in the past respectively. The analysis revealed a significant correlation between education and CAM use during therapy (r = 0.18; p = 0.02, and CAM use in the past (r = 0.17; p = 0.04. Of all patients using CAM during therapy, favored methods were food supplements (42.3%, vitamins/minerals (42.3%, massage (34.6%. Motivations are especially the reduction of side effect and stress, the positive effect of certain CAM-treatments on the immune system and tumor therapy. Results showed no difference between women and men. Most patients not having had any experience with CAM complain about the deficiency of information by their treating oncologist (31.4% as well as missing treatment possibilities (54.3%.Since many patients believe in study results demonstrating the efficacy of CAM, it stresses our task to develop innovative study protocols to investigate the outcomes of certain CAM on symptom reduction or other endpoints. Thus, prospective trials and innovative evidence-based treatment concepts to include CAM into high-end oncology is what patients demand and what a modern oncology center should offer.

An open CAM system for dentistry on the basis of China-made 5-axis simultaneous contouring CNC machine tool and industrial CAM software.

Science.gov (United States)

Lu, Li; Liu, Shusheng; Shi, Shenggen; Yang, Jianzhong

2011-10-01

China-made 5-axis simultaneous contouring CNC machine tool and domestically developed industrial computer-aided manufacture (CAM) technology were used for full crown fabrication and measurement of crown accuracy, with an attempt to establish an open CAM system for dental processing and to promote the introduction of domestic dental computer-aided design (CAD)/CAM system. Commercially available scanning equipment was used to make a basic digital tooth model after preparation of crown, and CAD software that comes with the scanning device was employed to design the crown by using domestic industrial CAM software to process the crown data in order to generate a solid model for machining purpose, and then China-made 5-axis simultaneous contouring CNC machine tool was used to complete machining of the whole crown and the internal accuracy of the crown internal was measured by using 3D-MicroCT. The results showed that China-made 5-axis simultaneous contouring CNC machine tool in combination with domestic industrial CAM technology can be used for crown making and the crown was well positioned in die. The internal accuracy was successfully measured by using 3D-MicroCT. It is concluded that an open CAM system for dentistry on the basis of China-made 5-axis simultaneous contouring CNC machine tool and domestic industrial CAM software has been established, and development of the system will promote the introduction of domestically-produced dental CAD/CAM system.

ChemCam on MSL 2009: first laser induced breakdown spectrometer for space science

Energy Technology Data Exchange (ETDEWEB)

Wiens, Roger C [Los Alamos National Laboratory

2008-01-01

ChemCam is one of the 10 instrument suites on the Mars Science Laboratory, a martian rover being built by Jet Propulsion Laboratory, for the next NASA mission to Mars (MSL 2009). ChemCam is an instrument package consisting of two remote sensing instruments: a Laser-Induced Breakdown Spectrometer (LIBS) and a Remote Micro-Imager (RMI). LIBS provides elemental compositions of rocks and soils, while the RMI places the LIBS analyses in their geomorphologic context. Both instruments rely on an autofocus capability to precisely focus on the chosen target, located at distances from the rover comprised between 1 and 9 m for LIBS, and 2 m and infinity for RMI. ChemCam will help determine which samples, within the vicinity of the MSL rover, are of sufficient interest to use the contact and in-situ instruments for further characterization. It will provide valuable analyses of samples that are inaccessible to contact and in-situ instruments, and of a much larger number of samples than can be done with this kind of instrument. ChemCam also has a capability to provide passive spectroscopy data of rocks and soils on Mars. ChemCam hardware consists of a Mast Unit (MU), provided by France, and a Body Unit (BU) built and tested in the USA. The Flight Model of the MU is assembled, tested and now available in the USA, while the BU is currently being assembled and tested. Both will be connected by the end of year '08 for end-to-end functional and performance tests, before delivery to JPL and assembly on the MSL rover. Launch is scheduled for October 09. After describing the concept of ChemCam, this presentation focuses on its French part, Mast Unit. The results presented show that Mast Unit is able to generate a plasma and collect its light, over the full applicable ranges of distances and temperatures on Mars.

The pineapple genome and the evolution of CAM photosynthesis.

Science.gov (United States)

Ming, Ray; VanBuren, Robert; Wai, Ching Man; Tang, Haibao; Schatz, Michael C; Bowers, John E; Lyons, Eric; Wang, Ming-Li; Chen, Jung; Biggers, Eric; Zhang, Jisen; Huang, Lixian; Zhang, Lingmao; Miao, Wenjing; Zhang, Jian; Ye, Zhangyao; Miao, Chenyong; Lin, Zhicong; Wang, Hao; Zhou, Hongye; Yim, Won C; Priest, Henry D; Zheng, Chunfang; Woodhouse, Margaret; Edger, Patrick P; Guyot, Romain; Guo, Hao-Bo; Guo, Hong; Zheng, Guangyong; Singh, Ratnesh; Sharma, Anupma; Min, Xiangjia; Zheng, Yun; Lee, Hayan; Gurtowski, James; Sedlazeck, Fritz J; Harkess, Alex; McKain, Michael R; Liao, Zhenyang; Fang, Jingping; Liu, Juan; Zhang, Xiaodan; Zhang, Qing; Hu, Weichang; Qin, Yuan; Wang, Kai; Chen, Li-Yu; Shirley, Neil; Lin, Yann-Rong; Liu, Li-Yu; Hernandez, Alvaro G; Wright, Chris L; Bulone, Vincent; Tuskan, Gerald A; Heath, Katy; Zee, Francis; Moore, Paul H; Sunkar, Ramanjulu; Leebens-Mack, James H; Mockler, Todd; Bennetzen, Jeffrey L; Freeling, Michael; Sankoff, David; Paterson, Andrew H; Zhu, Xinguang; Yang, Xiaohan; Smith, J Andrew C; Cushman, John C; Paull, Robert E; Yu, Qingyi

2015-12-01

Pineapple (Ananas comosus (L.) Merr.) is the most economically valuable crop possessing crassulacean acid metabolism (CAM), a photosynthetic carbon assimilation pathway with high water-use efficiency, and the second most important tropical fruit. We sequenced the genomes of pineapple varieties F153 and MD2 and a wild pineapple relative, Ananas bracteatus accession CB5. The pineapple genome has one fewer ancient whole-genome duplication event than sequenced grass genomes and a conserved karyotype with seven chromosomes from before the ρ duplication event. The pineapple lineage has transitioned from C3 photosynthesis to CAM, with CAM-related genes exhibiting a diel expression pattern in photosynthetic tissues. CAM pathway genes were enriched with cis-regulatory elements associated with the regulation of circadian clock genes, providing the first cis-regulatory link between CAM and circadian clock regulation. Pineapple CAM photosynthesis evolved by the reconfiguration of pathways in C3 plants, through the regulatory neofunctionalization of preexisting genes and not through the acquisition of neofunctionalized genes via whole-genome or tandem gene duplication.

Direct Imaging Search for Extrasolar Planets in the Pleiades

NARCIS (Netherlands)

Yamamoto, K.; et al., [Unknown; Thalmann, C.

2013-01-01

We carried out an imaging survey for extrasolar planets around stars in the Pleiades (125 Myr, 135 pc) in the H and KS bands using HiCIAO combined with adaptive optics, AO188, on the Subaru telescope. We found 13 companion candidates fainter than 14.5 mag in the H band around 9 stars. Five of these

Abnormal placental development and early embryonic lethality in EpCAM-null mice.

Directory of Open Access Journals (Sweden)

Keisuke Nagao

Full Text Available BACKGROUND: EpCAM (CD326 is encoded by the tacstd1 gene and expressed by a variety of normal and malignant epithelial cells and some leukocytes. Results of previous in vitro experiments suggested that EpCAM is an intercellular adhesion molecule. EpCAM has been extensively studied as a potential tumor marker and immunotherapy target, and more recent studies suggest that EpCAM expression may be characteristic of cancer stem cells. METHODOLOGY/PRINCIPAL FINDINGS: To gain insights into EpCAM function in vivo, we generated EpCAM -/- mice utilizing an embryonic stem cell line with a tacstd1 allele that had been disrupted. Gene trapping resulted in a protein comprised of the N-terminus of EpCAM encoded by 2 exons of the tacstd1 gene fused in frame to betageo. EpCAM +/- mice were viable and fertile and exhibited no obvious abnormalities. Examination of EpCAM +/- embryos revealed that betageo was expressed in several epithelial structures including developing ears (otocysts, eyes, branchial arches, gut, apical ectodermal ridges, lungs, pancreas, hair follicles and others. All EpCAM -/- mice died in utero by E12.5, and were small, developmentally delayed, and displayed prominent placental abnormalities. In developing placentas, EpCAM was expressed throughout the labyrinthine layer and by spongiotrophoblasts as well. Placentas of EpCAM -/- embryos were compact, with thin labyrinthine layers lacking prominent vascularity. Parietal trophoblast giant cells were also dramatically reduced in EpCAM -/- placentas. CONCLUSION: EpCAM was required for differentiation or survival of parietal trophoblast giant cells, normal development of the placental labyrinth and establishment of a competent maternal-fetal circulation. The findings in EpCAM-reporter mice suggest involvement of this molecule in development of vital organs including the gut, kidneys, pancreas, lungs, eyes, and limbs.

Abnormal placental development and early embryonic lethality in EpCAM-null mice.

Science.gov (United States)

Nagao, Keisuke; Zhu, Jianjian; Heneghan, Mallorie B; Hanson, Jeffrey C; Morasso, Maria I; Tessarollo, Lino; Mackem, Susan; Udey, Mark C

2009-12-31

EpCAM (CD326) is encoded by the tacstd1 gene and expressed by a variety of normal and malignant epithelial cells and some leukocytes. Results of previous in vitro experiments suggested that EpCAM is an intercellular adhesion molecule. EpCAM has been extensively studied as a potential tumor marker and immunotherapy target, and more recent studies suggest that EpCAM expression may be characteristic of cancer stem cells. To gain insights into EpCAM function in vivo, we generated EpCAM -/- mice utilizing an embryonic stem cell line with a tacstd1 allele that had been disrupted. Gene trapping resulted in a protein comprised of the N-terminus of EpCAM encoded by 2 exons of the tacstd1 gene fused in frame to betageo. EpCAM +/- mice were viable and fertile and exhibited no obvious abnormalities. Examination of EpCAM +/- embryos revealed that betageo was expressed in several epithelial structures including developing ears (otocysts), eyes, branchial arches, gut, apical ectodermal ridges, lungs, pancreas, hair follicles and others. All EpCAM -/- mice died in utero by E12.5, and were small, developmentally delayed, and displayed prominent placental abnormalities. In developing placentas, EpCAM was expressed throughout the labyrinthine layer and by spongiotrophoblasts as well. Placentas of EpCAM -/- embryos were compact, with thin labyrinthine layers lacking prominent vascularity. Parietal trophoblast giant cells were also dramatically reduced in EpCAM -/- placentas. EpCAM was required for differentiation or survival of parietal trophoblast giant cells, normal development of the placental labyrinth and establishment of a competent maternal-fetal circulation. The findings in EpCAM-reporter mice suggest involvement of this molecule in development of vital organs including the gut, kidneys, pancreas, lungs, eyes, and limbs.

CamOn: A Real-Time Autonomous Camera Control System

DEFF Research Database (Denmark)

Burelli, Paolo; Jhala, Arnav Harish

2009-01-01

This demonstration presents CamOn, an autonomous cam- era control system for real-time 3D games. CamOn employs multiple Artificial Potential Fields (APFs), a robot motion planning technique, to control both the location and orienta- tion of the camera. Scene geometry from the 3D environment...... contributes to the potential field that is used to determine po- sition and movement of the camera. Composition constraints for the camera are modelled as potential fields for controlling the view target of the camera. CamOn combines the compositional benefits of constraint- based camera systems, and improves...

Hα Intensity Map of the Repeating Fast Radio Burst FRB 121102 Host Galaxy from Subaru/Kyoto 3DII AO-assisted Optical Integral-field Spectroscopy

Science.gov (United States)

Kokubo, Mitsuru; Mitsuda, Kazuma; Sugai, Hajime; Ozaki, Shinobu; Minowa, Yosuke; Hattori, Takashi; Hayano, Yutaka; Matsubayashi, Kazuya; Shimono, Atsushi; Sako, Shigeyuki; Doi, Mamoru

2017-08-01

We present the Hα intensity map of the host galaxy of the repeating fast radio burst FRB 121102 at a redshift of z = 0.193 obtained with the AO-assisted Kyoto 3DII optical integral-field unit mounted on the 8.2 m Subaru Telescope. We detected a compact Hα-emitting (I.e., star-forming) region in the galaxy, which has a much smaller angular size (GMOS z\\prime -band image (≃ 1\\buildrel{\\prime\\prime}\\over{.} 4 (4.6 kpc) at FWHM with ellipticity b/a=0.45). The spatial offset between the centroid of the Hα emission region and the position of the radio bursts is 0\\buildrel{\\prime\\prime}\\over{.} 08+/- 0\\buildrel{\\prime\\prime}\\over{.} 02 (0.26 ± 0.07 kpc), indicating that FRB 121102 is located within the star-forming region. This close spatial association of FRB 121102 with the star-forming region is consistent with expectations from young pulsar/magnetar models for FRB 121102, and it also suggests that the observed Hα emission region can make a major dispersion measure (DM) contribution to the host galaxy DM component of FRB 121102. Nevertheless, the largest possible value of the DM contribution from the Hα emission region inferred from our observations still requires a significant amount of ionized baryons in intergalactic medium (IGM; the so-called “missing” baryons) as the DM source of FRB 121102, and we obtain a 90% confidence level lower limit on the cosmic baryon density in the IGM in the low-redshift universe as {{{Ω }}}{IGM}> 0.012. Based on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan.

Knowledge and training needs among Danish nurses about CAM

DEFF Research Database (Denmark)

Lunde, Anita

2010-01-01

Background: The increased use of CAM among the Danish population is well documented as are patient’s requests to discuss CAM with a healthcare professional. It is suggested that among different groups of healthcare professionals nurses are the most “open minded” about CAM. This makes it important...... to explore nurses’ knowledge about CAM and their needs for training. Methods: Similar to international investigations a Danish “CAM-knowledge” questionnaire was developed that included multiple choice, yes/no and 5 points scale answers. Validity was established through initial pilot testing. Contacts...... to a randomized sample of 2500 nurses were established through the Danish Nurses Foundation. The questionnaires were mailed by post with the possibility of anonymous return. The data material was analyzed using non-parametic methods. Results: The response rate was 67 % and 1458 completed questionnaires were...

Test plan for FY-91 alpha CAM evaluation

International Nuclear Information System (INIS)

Winberg, M.R.

1991-03-01

This report describes the test plan for evaluating the Merlin Gerin, Inc., Edgar alpha continuous air monitor (CAM) and associated analysis system to be conducted by Idaho National Engineering Laboratory (INEL) for the Department of Energy. INEL has evaluated other commercial alpha CAM systems to detect transuranic contaminants during waste handling and retrieval operations. This test plan outlines experimental methods, sampling methods, sampling and analysis techniques, and equipment needed and safety and quality requirements to test the commercial CAM. 8 refs., 3 figs

CAM Stochastic Volatility Model for Option Pricing

Directory of Open Access Journals (Sweden)

Wanwan Huang

2016-01-01

Full Text Available The coupled additive and multiplicative (CAM noises model is a stochastic volatility model for derivative pricing. Unlike the other stochastic volatility models in the literature, the CAM model uses two Brownian motions, one multiplicative and one additive, to model the volatility process. We provide empirical evidence that suggests a nontrivial relationship between the kurtosis and skewness of asset prices and that the CAM model is able to capture this relationship, whereas the traditional stochastic volatility models cannot. We introduce a control variate method and Monte Carlo estimators for some of the sensitivities (Greeks of the model. We also derive an approximation for the characteristic function of the model.

Resin-composite blocks for dental CAD/CAM applications.

Science.gov (United States)

Ruse, N D; Sadoun, M J

2014-12-01

Advances in digital impression technology and manufacturing processes have led to a dramatic paradigm shift in dentistry and to the widespread use of computer-aided design/computer-aided manufacturing (CAD/CAM) in the fabrication of indirect dental restorations. Research and development in materials suitable for CAD/CAM applications are currently the most active field in dental materials. Two classes of materials are used in the production of CAD/CAM restorations: glass-ceramics/ceramics and resin composites. While glass-ceramics/ceramics have overall superior mechanical and esthetic properties, resin-composite materials may offer significant advantages related to their machinability and intra-oral reparability. This review summarizes recent developments in resin-composite materials for CAD/CAM applications, focusing on both commercial and experimental materials. © International & American Associations for Dental Research.

Seasonal variation of the radial brightness contrast of Saturn's rings viewed in mid-infrared by Subaru/COMICS

Science.gov (United States)

Fujiwara, Hideaki; Morishima, Ryuji; Fujiyoshi, Takuya; Yamashita, Takuya

2017-03-01

Aims: This paper investigates the mid-infrared (MIR) characteristics of Saturn's rings. Methods: We collected and analyzed MIR high spatial resolution images of Saturn's rings obtained in January 2008 and April 2005 with the COoled Mid-Infrared Camera and Spectrometer (COMICS) mounted on the Subaru Telescope, and investigated the spatial variation in the surface brightness of the rings in multiple bands in the MIR. We also composed the spectral energy distributions (SEDs) of the C, B, and A rings and the Cassini Division, and estimated the temperatures of the rings from the SEDs assuming the optical depths. Results: We found that the C ring and the Cassini Division were warmer than the B and A rings in 2008, which could be accounted for by their lower albedos, lower optical depths, and smaller self-shadowing effect. We also fonud that the C ring and the Cassini Division were considerably brighter than the B and A rings in the MIR in 2008 and the radial contrast of the ring brightness is the inverse of that in 2005, which is interpreted as a result of a seasonal effect with changing elevations of the Sun and observer above the ring plane. The reduced images (FITS files) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/599/A29

The use of economic evaluation in CAM: an introductory framework.

Science.gov (United States)

Ford, Emily; Solomon, Daniela; Adams, Jon; Graves, Nicholas

2010-11-11

For CAM to feature prominently in health care decision-making there is a need to expand the evidence-base and to further incorporate economic evaluation into research priorities.In a world of scarce health care resources and an emphasis on efficiency and clinical efficacy, CAM, as indeed do all other treatments, requires rigorous evaluation to be considered in budget decision-making. Economic evaluation provides the tools to measure the costs and health consequences of CAM interventions and thereby inform decision making. This article offers CAM researchers an introductory framework for understanding, undertaking and disseminating economic evaluation. The types of economic evaluation available for the study of CAM are discussed, and decision modelling is introduced as a method for economic evaluation with much potential for use in CAM. Two types of decision models are introduced, decision trees and Markov models, along with a worked example of how each method is used to examine costs and health consequences. This is followed by a discussion of how this information is used by decision makers. Undoubtedly, economic evaluation methods form an important part of health care decision making. Without formal training it can seem a daunting task to consider economic evaluation, however, multidisciplinary teams provide an opportunity for health economists, CAM practitioners and other interested researchers, to work together to further develop the economic evaluation of CAM.

The use of economic evaluation in CAM: an introductory framework

Science.gov (United States)

2010-01-01

Background For CAM to feature prominently in health care decision-making there is a need to expand the evidence-base and to further incorporate economic evaluation into research priorities. In a world of scarce health care resources and an emphasis on efficiency and clinical efficacy, CAM, as indeed do all other treatments, requires rigorous evaluation to be considered in budget decision-making. Methods Economic evaluation provides the tools to measure the costs and health consequences of CAM interventions and thereby inform decision making. This article offers CAM researchers an introductory framework for understanding, undertaking and disseminating economic evaluation. The types of economic evaluation available for the study of CAM are discussed, and decision modelling is introduced as a method for economic evaluation with much potential for use in CAM. Two types of decision models are introduced, decision trees and Markov models, along with a worked example of how each method is used to examine costs and health consequences. This is followed by a discussion of how this information is used by decision makers. Conclusions Undoubtedly, economic evaluation methods form an important part of health care decision making. Without formal training it can seem a daunting task to consider economic evaluation, however, multidisciplinary teams provide an opportunity for health economists, CAM practitioners and other interested researchers, to work together to further develop the economic evaluation of CAM. PMID:21067622

The use of economic evaluation in CAM: an introductory framework

Directory of Open Access Journals (Sweden)

Adams Jon

2010-11-01

Full Text Available Abstract Background For CAM to feature prominently in health care decision-making there is a need to expand the evidence-base and to further incorporate economic evaluation into research priorities. In a world of scarce health care resources and an emphasis on efficiency and clinical efficacy, CAM, as indeed do all other treatments, requires rigorous evaluation to be considered in budget decision-making. Methods Economic evaluation provides the tools to measure the costs and health consequences of CAM interventions and thereby inform decision making. This article offers CAM researchers an introductory framework for understanding, undertaking and disseminating economic evaluation. The types of economic evaluation available for the study of CAM are discussed, and decision modelling is introduced as a method for economic evaluation with much potential for use in CAM. Two types of decision models are introduced, decision trees and Markov models, along with a worked example of how each method is used to examine costs and health consequences. This is followed by a discussion of how this information is used by decision makers. Conclusions Undoubtedly, economic evaluation methods form an important part of health care decision making. Without formal training it can seem a daunting task to consider economic evaluation, however, multidisciplinary teams provide an opportunity for health economists, CAM practitioners and other interested researchers, to work together to further develop the economic evaluation of CAM.

Aquatic CAM photosynthesis: a brief history of its discovery

Science.gov (United States)

Keeley, Jon E.

2014-01-01

Aquatic CAM (Crassulacean Acid Metabolism) photosynthesis was discovered while investigating an unrelated biochemical pathway concerned with anaerobic metabolism. George Bowes was a significant contributor to this project early in its infancy. Not only did he provide me with some valuable perspectives on peer review rejections, but by working with his gas exchange system I was able to take our initial observations of diel fluctuations in malic acid to the next level, showing this aquatic plant exhibited dark CO2 uptake. CAM is universal in all aquatic species of the worldwide Lycophyta genus Isoetes and non-existent in terrestrial Isoetes. Outside of this genus aquatic CAM has a limited occurrence in three other families, including the Crassulaceae. This discovery led to fascinating adventures in the highlands of the Peruvian Andes in search of Stylites, a terrestrial relative of Isoetes. Stylites is a plant that is hermetically sealed from the atmosphere and obtains all of its carbon from terrestrial sources and recycles carbon through CAM. Considering the Mesozoic origin of Isoetes in shallow pools, coupled with the fact that aquatic Isoetes universally possess CAM, suggests the earliest evolution of CAM photosynthesis was most likely not in terrestrial plants.

Case studies in therapeutic SenseCam use aimed at identity maintenance in early stage dementia

OpenAIRE

Piasek, Paulina

2015-01-01

In the absence of a medical cure for memory loss new technologies specialised in pervasive imaging are being incorporated into interventions for dementia. The practice of lifelogging is a digital capture of life experiences typically through mobile devices such as SenseCam. The lightweight wearable digital camera passively captures about 3,000 images a day. Lifelogging results in personal, recent prompts, potentially encouraging sharing of personal memories. This research investigated the i...

PillCam ESO in esophageal studies: improved diagnostic yield of 14 frames per second (fps) compared with 4 fps.

Science.gov (United States)

Koslowsky, B; Jacob, H; Eliakim, R; Adler, S N

2006-01-01

Capsule endoscopy, using the PillCam ESO and sending images at a rate of 4 frames per second (fps), has a high sensitivity and specificity in diagnosing gastroesophageal reflux disease (GERD) lesions. We tested a new device which produces images at a rate of 14 fps. The diagnostic performance and esophageal visualization of these two devices were compared. 42 patients with GERD symptoms and eight patients with a history of Barrett's esophagus had an esophagogastroduodenoscopy (EGD). All patients underwent capsule endoscopy of the esophagus within 1 hour prior to EGD. The first 25 patients had a capsule endoscopy examination with the 4-fps device. The following 25 patients underwent capsule endoscopy under identical conditions but using the 14-fps device. The reader of the capsule endoscopy study was blinded to the EGD findings. A diagnosis of GERD or Barrett's esophagus was established with EGD. The findings at capsule endoscopy were compared with the EGD findings. We also examined how frequently the esophagus in its entirety was visualized by these two devices. The 4-fps device diagnosed 16/19 cases of esophageal erosions or ulcers (sensitivity 84 %) and 6/8 cases of Barrett's esophagus (sensitivity 75 %). The 14-fps capsule diagnosed 16/16 cases of esophageal ulcers or erosions and 7/7 cases of Barrett's esophagus (sensitivity 100 %). The total diagnostic miss rate in the 4-fps group was 5/27 (18 %) whereas the diagnostic miss rate in the 14-fps group was 0/23 (0 %) P fps group and in 20/25 patients (80 %) in the 14-fps group ( P fps device and in 19/25 (76 %) by the 14-fps device ( P fps PillCam ESO capsule is consistent with the data obtained from fluoroscopic studies of swallowed PillCam capsules, showing that capsule speed may reach 20 cm/s. For the 14-fps PillCam this means one image transmitted per 3-cm segment at maximal capsule speed, therefore still allowing for full visualization of the entire esophagus. Capsule endoscopy using the 14-fps PillCam ESO

Different CAD/CAM-processing routes for zirconia restorations: influence on fitting accuracy.

Science.gov (United States)

Kohorst, Philipp; Junghanns, Janet; Dittmer, Marc P; Borchers, Lothar; Stiesch, Meike

2011-08-01

The aim of the present in vitro study was to evaluate the influence of different processing routes on the fitting accuracy of four-unit zirconia fixed dental prostheses (FDPs) fabricated by computer-aided design/computer-aided manufacturing (CAD/CAM). Three groups of zirconia frameworks with ten specimens each were fabricated. Frameworks of one group (CerconCAM) were produced by means of a laboratory CAM-only system. The other frameworks were made with different CAD/CAM systems; on the one hand by in-laboratory production (CerconCAD/CAM) and on the other hand by centralized production in a milling center (Compartis) after forwarding geometrical data. Frameworks were then veneered with the recommended ceramics, and marginal accuracy was determined using a replica technique. Horizontal marginal discrepancy, vertical marginal discrepancy, absolute marginal discrepancy, and marginal gap were evaluated. Statistical analyses were performed by one-way analysis of variance (ANOVA), with the level of significance chosen at 0.05. Mean horizontal discrepancies ranged between 22 μm (CerconCAM) and 58 μm (Compartis), vertical discrepancies ranged between 63 μm (CerconCAD/CAM) and 162 μm (CerconCAM), and absolute marginal discrepancies ranged between 94 μm (CerconCAD/CAM) and 181 μm (CerconCAM). The marginal gap varied between 72 μm (CerconCAD/CAM) and 112 μm (CerconCAM, Compartis). Statistical analysis revealed that, with all measurements, the marginal accuracy of the zirconia FDPs was significantly influenced by the processing route used (p manufacture of four-unit FDPs.

Evaluating rare amino acid substitutions (RGC_CAMs in a yeast model clade.

Directory of Open Access Journals (Sweden)

Kenneth Polzin

Full Text Available When inferring phylogenetic relationships, not all sites in a sequence alignment are equally informative. One recently proposed approach that takes advantage of this inequality relies on sites that contain amino acids whose replacement requires multiple substitutions. Identifying these so-called RGC_CAM substitutions (after Rare Genomic Changes as Conserved Amino acids-Multiple substitutions requires that, first, at any given site in the amino acid sequence alignment, there must be a minimum of two different amino acids; second, each amino acid must be present in at least two taxa; and third, the amino acids must require a minimum of two nucleotide substitutions to replace each other. Although theory suggests that RGC_CAM substitutions are expected to be rare and less likely to be homoplastic, the informativeness of RGC_CAM substitutions has not been extensively evaluated in biological data sets. We investigated the quality of RGC_CAM substitutions by examining their degree of homoplasy and internode certainty in nearly 2.7 million aligned amino acid sites from 5,261 proteins from five species belonging to the yeast Saccharomyces sensu stricto clade whose phylogeny is well-established. We identified 2,647 sites containing RGC_CAM substitutions, a number that contrasts sharply with the 100,887 sites containing RGC_non-CAM substitutions (i.e., changes between amino acids that require only a single nucleotide substitution. We found that RGC_CAM substitutions had significantly lower homoplasy than RGC_non-CAM ones; specifically RGC_CAM substitutions showed a per-site average homoplasy index of 0.100, whereas RGC_non-CAM substitutions had a homoplasy index of 0.215. Internode certainty values were also higher for sites containing RGC_CAM substitutions than for RGC_non-CAM ones. These results suggest that RGC_CAM substitutions possess a strong phylogenetic signal and are useful markers for phylogenetic inference despite their rarity.

PulseCam: high-resolution blood perfusion imaging using a camera and a pulse oximeter.

Science.gov (United States)

Kumar, Mayank; Suliburk, James; Veeraraghavan, Ashok; Sabharwal, Ashutosh

2016-08-01

Measuring blood perfusion is important in medical care as an indicator of injury and disease. However, currently available devices to measure blood perfusion like laser Doppler flowmetry are bulky, expensive, and cumbersome to use. An alternative low-cost and portable camera-based blood perfusion measurement system has recently been proposed, but such camera-only system produces noisy low-resolution blood perfusion maps. In this paper, we propose a new multi-sensor modality, named PulseCam, for measuring blood perfusion by combining a traditional pulse oximeter with a video camera in a unique way to provide low noise and high-resolution blood perfusion maps. Our proposed multi-sensor modality improves per pixel signal to noise ratio of measured perfusion map by up to 3 dB and improves the spatial resolution by 2 - 3 times compared to best known camera-only methods. Blood perfusion measured in the palm using our PulseCam setup during a post-occlusive reactive hyperemia (PORH) test replicates standard PORH response curve measured using laser Doppler flowmetry device but with much lower cost and a portable setup making it suitable for further development as a clinical device.

Model Documentation for the MiniCAM

Energy Technology Data Exchange (ETDEWEB)

Brenkert, Antoinette L.; Smith, Steven J.; Kim, Son H.; Pitcher, Hugh M.

2003-07-17

The MiniCAM, short for the Mini-Climate Assessment Model, is an integrated assessment model of moderate complexity focused on energy and agriculture sectors. The model produces emissions of greenhouse gases (carbon dioxide, methane and nitrous oxide) and other radiatively important substances such as sulfur dioxide. Through incorporation of the simple climate model MAGICC, the consequences of these emissions for climate change and sea-level rise can be examined. The MiniCAM is designed to be fast and flexible.

Clustering of galaxies around AGNs in the HSC Wide survey

Science.gov (United States)

Shirasaki, Yuji; Akiyama, Masayuki; Nagao, Tohru; Toba, Yoshiki; He, Wanqiu; Ohishi, Masatoshi; Mizumoto, Yoshihiko; Miyazaki, Satoshi; Nishizawa, Atsushi J.; Usuda, Tomonori

2018-01-01

We have measured the clustering of galaxies around active galactic nuclei (AGNs) for which single-epoch virial masses of the super-massive black hole (SMBH) are available to investigate the relation between the large-scale environment of AGNs and the evolution of SMBHs. The AGN samples used in this work were derived from the Sloan Digital Sky Survey (SDSS) observations and the galaxy samples were from the 240 deg2 S15b data of the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP). The investigated redshift range is 0.6-3.0, and the masses of the SMBHs lie in the range 107.5-1010 M⊙. The absolute magnitude of the galaxy samples reaches to Mλ310 ˜ -18 at rest-frame wavelength 310 nm for the low-redshift end of the samples. More than 70% of the galaxies in the analysis are blue. We found a significant dependence of the cross-correlation length on redshift, which primarily reflects the brightness-dependence of the galaxy clustering. At the lowest redshifts the cross-correlation length increases from 7 h-1 Mpc around Mλ310 = -19 mag to >10 h-1 Mpc beyond Mλ310 = -20 mag. No significant dependence of the cross-correlation length on BH mass was found for whole galaxy samples dominated by blue galaxies, while there was an indication of BH mass dependence in the cross-correlation with red galaxies. These results provides a picture of the environment of AGNs studied in this paper being enriched with blue star-forming galaxies, and a fraction of the galaxies are evolving into red galaxies along with the evolution of SMBHs in that system.

Treatment Preferences for CAM in Children with Chronic Pain

OpenAIRE

Tsao, Jennie C. I.; Meldrum, Marcia; Kim, Su C.; Jacob, Margaret C.; Zeltzer, Lonnie K.

2006-01-01

CAM therapies have become increasingly popular in pediatric populations. Yet, little is known about children's preferences for CAM. This study examined treatment preferences in chronic pediatric pain patients offered a choice of CAM therapies for their pain. Participants were 129 children (94 girls) (mean age = 14.5 years ± 2.4; range = 8–18 years) presenting at a multidisciplinary, tertiary clinic specializing in pediatric chronic pain. Bivariate and multivariate analyses were used to examin...

Biodistribution studies of epithelial cell adhesion molecule (EpCAM)-directed monoclonal antibodies in the EpCAM-transgenic mouse tumor model

NARCIS (Netherlands)

Kosterink, Jos G. W.; McLaughlin, Pamela M. J.; Lub-de Hooge, Marjolijn N.; Hendrikse, Harry H.; Van Zanten, Jacoba; Van Garderen, Evert; Harmsen, Martin C.; De Leij, Lou F. M. H.

2007-01-01

The human pancarcinoma-associated epithelial cell adhesion molecule (EpCAM) (EGP-2, CO17-1A) is a well-known target for carcinoma-directed immunotherapy. Mouse-derived mAbs directed to EpCAM have been used to treat colon carcinoma patients showing well-tolerable toxic side effects but limited

The ChemCam Instrument Suite on the Mars Science Laboratory (MSL) Rover: Science Objectives and Mast Unit Description

Science.gov (United States)

Maurice, S.; Wiens, R.C.; Saccoccio, M.; Barraclough, B.; Gasnault, O.; Forni, O.; Mangold, N.; Baratoux, D.; Bender, S.; Berger, G.; Bernardin, J.; Berthé, M.; Bridges, N.; Blaney, D.; Bouyé, M.; Caïs, P.; Clark, B.; Clegg, S.; Cousin, A.; Cremers, D.; Cros, A.; DeFlores, L.; Derycke, C.; Dingler, B.; Dromart, G.; Dubois, B.; Dupieux, M.; Durand, E.; d'Uston, L.; Fabre, C.; Faure, B.; Gaboriaud, A.; Gharsa, T.; Herkenhoff, K.; Kan, E.; Kirkland, L.; Kouach, D.; Lacour, J.-L.; Langevin, Y.; Lasue, J.; Le Mouélic, S.; Lescure, M.; Lewin, E.; Limonadi, D.; Manhès, G.; Mauchien, P.; McKay, C.; Meslin, P.-Y.; Michel, Y.; Miller, E.; Newsom, Horton E.; Orttner, G.; Paillet, A.; Parès, L.; Parot, Y.; Pérez, R.; Pinet, P.; Poitrasson, F.; Quertier, B.; Sallé, B.; Sotin, Christophe; Sautter, V.; Séran, H.; Simmonds, J.J.; Sirven, J.-B.; Stiglich, R.; Striebig, N.; Thocaven, J.-J.; Toplis, M.J.; Vaniman, D.

2012-01-01

ChemCam is a remote sensing instrument suite on board the "Curiosity" rover (NASA) that uses Laser-Induced Breakdown Spectroscopy (LIBS) to provide the elemental composition of soils and rocks at the surface of Mars from a distance of 1.3 to 7 m, and a telescopic imager to return high resolution context and micro-images at distances greater than 1.16 m. We describe five analytical capabilities: rock classification, quantitative composition, depth profiling, context imaging, and passive spectroscopy. They serve as a toolbox to address most of the science questions at Gale crater. ChemCam consists of a Mast-Unit (laser, telescope, camera, and electronics) and a Body-Unit (spectrometers, digital processing unit, and optical demultiplexer), which are connected by an optical fiber and an electrical interface. We then report on the development, integration, and testing of the Mast-Unit, and summarize some key characteristics of ChemCam. This confirmed that nominal or better than nominal performances were achieved for critical parameters, in particular power density (>1 GW/cm2). The analysis spot diameter varies from 350 μm at 2 m to 550 μm at 7 m distance. For remote imaging, the camera field of view is 20 mrad for 1024×1024 pixels. Field tests demonstrated that the resolution (˜90 μrad) made it possible to identify laser shots on a wide variety of images. This is sufficient for visualizing laser shot pits and textures of rocks and soils. An auto-exposure capability optimizes the dynamical range of the images. Dedicated hardware and software focus the telescope, with precision that is appropriate for the LIBS and imaging depths-of-field. The light emitted by the plasma is collected and sent to the Body-Unit via a 6 m optical fiber. The companion to this paper (Wiens et al. this issue) reports on the development of the Body-Unit, on the analysis of the emitted light, and on the good match between instrument performance and science specifications.

The application of CAD / CAM technology in Dentistry

Science.gov (United States)

Susic, I.; Travar, M.; Susic, M.

2017-05-01

Information and communication technologies have found their application in the healthcare sector, including the frameworks of modern dentistry. CAD / CAM application in dentistry is the process by which is attained finished dental restoration through fine milling process of ready ceramic blocks. CAD / CAM is an acronym of english words Computer-Aided-Design (CAD) / Computer-Aided-Manufacture (CAM), respectively dental computer aided design and computer aided manufacture of inlays, onlays, crowns and bridges. CAD / CAM technology essentially allows you to create a two-dimensional and three-dimensional models and their materialization by numerical controlled machines. In order to operate more efficiently, reduce costs, increase user/patient satisfaction and ultimately achieve profits, many dental offices in the world have their attention focused on implementation of modern IT solutions in everyday practice. In addition to the specialized clinic management software, inventory control, etc., or hardware such as the use of lasers in cosmetic dentistry or intraoral scanning, recently the importance is given to the application of CAD / CAM technology in the field of prosthetic. After the removal of pathologically altered tooth structure, it is necessary to achieve restoration that will be most similar to the anatomy of a natural tooth. Applying CAD / CAM technology on applicable ceramic blocks it can be obtained very quick, but also very accurate restoration, in the forms of inlays, onlays, bridges and crowns. The paper presents the advantages of using this technology as well as satisfaction of the patients and dentists by using systems as: Cercon, Celay, Cerec, Lava, Everest, which represent imperative of modern dentistry in creating fixed dental restorations.

Effectiveness of CAM therapy: understanding the evidence.

Science.gov (United States)

Staud, Roland

2011-02-01

By definition, complementary and alternative medicine (CAM) attempts to diagnose and treat illnesses in unconventional ways. CAM has been classified as: (1) alternative medical systems (eg, traditional Chinese medicine [including acupuncture], naturopathic medicine, ayurvedic medicine, and homeopathy); (2) biologic-based therapies (eg, herbal, special dietary, and individual biologic treatments); (3) energy therapies (eg, Reiki, therapeutic touch, magnet therapy, Qi Gong, and intercessory prayer); (4) manipulative and body-based systems (eg, chiropractic, osteopathy, and massage); and (5) mind-body interventions (eg, meditation, biofeedback, hypnotherapy, and the relaxation response). This review focuses on how to assess the effectiveness of CAM therapies for chronic musculoskeletal pains, emphasizing the role of specific and nonspecific analgesic mechanisms, including placebo. Copyright © 2011 Elsevier Inc. All rights reserved.

Prevalence of Cam Morphology in Females with Femoroacetabular Impingement

Directory of Open Access Journals (Sweden)

David M Levy

2015-12-01

Full Text Available Cam and pincer are two common morphologies responsible for femoroacetabular impingement. Previous literature has reported that cam deformity is predominantly a male morphology, while being significantly less common in females. The purpose of this study was to determine the prevalence of cam morphology in female subjects diagnosed with symptomatic FAI. All females presenting to the senior author’s clinic diagnosed with symptomatic FAI between December 2006 and Cam and pincer are two common morphologies responsible for femoroacetabular impingement. Previous literature has reported that cam deformity is predominantly a male morphology, while being significantly less common in females. Cam morphology is commonly assessed with the alpha angle, measured on radiographs. The purpose of this study was to determine the prevalence of cam morphology utilizing the alpha angle in female subjects diagnosed with symptomatic FAI. All females presenting to the senior author’s clinic diagnosed with symptomatic FAI between December 2006 and January 2013 were retrospectively reviewed. Alpha (α angles were measured on AP (anteroposterior and lateral (Dunn 90°, cross-table lateral, and/or frog-leg lateral plain radiographs by two blinded physicians, and the largest measured angle was used. Using Gosvig et al.’s classification, alpha angle was characterized as (pathologic > 57°, borderline (51-56°, subtle (46-50°, very subtle (43-45°, or normal (≤42°. Three hundred and ninety-one patients (438 hips were analyzed (age 36.2 ± 12.3 years. Among the hips included, 35.6% were normal, 14.6% pathologic, 15.1% borderline, 14.6% subtle, and 20.1% very subtle. There was no correlation between alpha angle and patient age (R = 0.17 or body mass index (BMI (R = 0.05. The intraclass correlation coefficient (ICC for α-angle measurements was 0.84. Sixty-four percent of females in this cohort had an alpha angle > 42°. Subtle cam deformity plays a significant role in

CAM for Pediatric Pain: What is State-of-the-Research?

Directory of Open Access Journals (Sweden)

Jennie C. I. Tsao

2006-01-01

Full Text Available Previously, we reviewed the evidence for the efficacy of CAM approaches for pediatric pain (volume 2; issue 2; 2005 using criteria developed by the American Psychological Association Division 12 Task Force. Our review focused on CAM modalities that had been tested with at least one controlled trial or multiple baseline study. In addition, only those trials in which children comprised the study sample were included. Thus, several CAM modalities were not included in our review. Key ethical and other reasons for the limited literature on CAM for pediatric pain as well as directions for future studies are discussed.

An Innovative Radiation Hardened CAM Architecture

CERN Document Server

Shojaii, Seyed Ruhollah; The ATLAS collaboration

2018-01-01

This article describes an innovative Content Addressable Memory (CAM) cell with radiation hardened (RH) architecture. The RH-CAM is designed in a commercial 28 nm CMOS technology. The circuit has been simulated in worst-case conditions, and the effects due to single particles have been analyzed by injecting a current pulse into a circuit node. The proposed architecture is suitable for on-time pattern recognition tasks in harsh environments, such as front-end electronics in hadron colliders and in space applications.

Use of Complementary and Alternative Medicine (CAM) as Part of the Oncological Treatment: Survey about Patients? Attitude towards CAM in a University-Based Oncology Center in Germany

OpenAIRE

Kessel, Kerstin A.; Lettner, Sabrina; Kessel, Carmen; Bier, Henning; Biedermann, Tilo; Friess, Helmut; Herrschbach, Peter; Gschwend, J?rgen E.; Meyer, Bernhard; Peschel, Christian; Schmid, Roland; Schwaiger, Markus; Wolff, Klaus-Dietrich; Combs, Stephanie E.

2016-01-01

Introduction To understand if and which patients would be open-minded to Complementary and Alternative Medicine (CAM) use parallel to their oncological treatment. Moreover, we sought to determine which methods are most accepted and which are the primary motivators to use CAM. Methods We developed and anonymously conducted a questionnaire for patients in the oncology center (TU Munich). Questions focus on different CAM methods, previous experiences, and willingness to apply or use CAM when off...

Camões e a cosmogonia

Science.gov (United States)

Costa, J. M.

2003-08-01

Os Lusíadas, escrito por Luis de Camões em 1572, é um poema épico renascentista e a visão Cosmogônica do autor é apresentada, principalmente, no último canto do poema, quando Tétis mostra ao Gama a Máquina do Mundo. A Cosmogonia de Camões neste poema reflete uma visão de uma época de transição, que ainda não incorporou os elementos da revolução Copernicana. É uma visão Grego- Ptolomaica e também medieval. O poeta guia-se pela tradução e notas feita por Pedro Nunes, inventor do Nonio, do Tratado da Esfera "De Sphaera" do Astrônomo Inglês John Holywood, mais conhecido pelo nome latinizado de Johannes Sacrobosco. Outra provável fonte de Camões, de acordo com Luciano Antonio Pereira da Silva em Astronomia de os Lusíadas, é o "Theoricae novae Planetarum" (1460) do astrólogo Alemão Jorge Purbáquio (1423 - 1461). A Astronomia de Os Lusíadas representa a ciência do tempo de Camões. Camões nunca emprega a palavra constelação e seu catálogo é bastante completo. A Máquina do Mundo tem a Terra no centro. Em redor, em círculos concêntricos, a lua (Diana), Mercúrio, Vênus, o Sol (Febo), Marte, Júpiter e Saturno. Envolvendo estes astros tem o firmamento seguido pelo "Céu Áqueo" ou cristalino, depois o 1o Móbil, esfera que arrasta todas as outras consigo. Este trabalho, multidisciplinar, serve tanto para ensinar aos alunos da Física como das Ciências Humanas, a concepção de mundo do renascimento de uma forma belamente poética em versos decassílabos Este trabalho também ajuda na apreciação do maior clássico da língua portuguesa e mostra como as Ciências e as artes, em geral, estão correlacionadas e refletem a visão de mundo da época em que foi produzida.

Biofuel crops with CAM photosynthesis: Economic potential on moisture-limited lands

Science.gov (United States)

Bartlett, Mark; Hartzell, Samantha; Porporato, Amilcare

2017-04-01

As the demand for food and renewable energy increases, the intelligent utilization of marginal lands is becoming increasingly critical. In marginal lands classified by limited rainfall or soil salinity, the cultivation of traditional C3 and C4 photosynthesis crops often is economically infeasible. However, in such lands, nontraditional crops with crassulacean acid metabolism (CAM) photosynthesis show great economic potential for cultivation. CAM crops including Opuntia (prickly pear) and Ananas (pineapple) achieve a water use efficiency which is three fold higher than C4 crops such as corn and 6-fold higher than C3 crops such as wheat, leading to a comparable annual productivity with only 20% of the water demand. This feature, combined with a shallow rooting depth and a high water storage capacity, allows CAM plants to take advantage of small, infrequent rainfall amounts in shallow, quickly draining soils. Furthermore, CAM plants typically have properties (e.g., high content of non-structural carbohydrates) that are favorable for biofuel production. Here, for marginal lands characterized by low soil moisture availability and/or high salinity, we assess the potential productivity and economic benefits of CAM plants. CAM productivity is estimated using a recently developed model which simulates CAM photosynthesis under a range of soil and climate conditions. From these results, we compare the energy and water resource inputs required by CAM plants to those required by more traditional C3 and C4 crops (corn, wheat, sorghum), and we evaluate the economic potential of CAM crops as sources of food, fodder, or biofuel in marginal soils. As precipitation events become more intense and infrequent, we show that even though marginal land area may increase, CAM crop cultivation shows great promise for maintaining high productivity with minimal water inputs. Our analysis indicates that on marginal lands, widespread cultivation of CAM crops as biofuel feedstock may help

Scleroderma, Stress and CAM Utilization

Directory of Open Access Journals (Sweden)

Ka-Kit Hui

2009-01-01

Full Text Available Scleroderma is an autoimmune disease influenced by interplay among genetic and environmental factors, of which one is stress. Complementary and alternative medicine (CAM is frequently used to treat stress and those diseases in which stress has been implicated. Results are presented from a survey of patients with scleroderma. Respondents were a convenient sample of those attending a national conference in Las Vegas in 2002. Findings implicate stress in the onset, continuation and exacerbation of scleroderma. The implication is that CAM providers may be filling an important patient need in their provision of services that identify and treat stress and its related disorders.

Trend and application of CAD/CAM system

International Nuclear Information System (INIS)

Kang, Man Ok

1984-09-01

This report is about trend and application of CAD/CAM system, giving descriptions of computer aided design which helps construction, engineering and drafting tasks. It also tells of computer aided manufacturing related general design of manufactures, which includes process design, production management, decision of work technology, processing. The need and application of CAD/CAM system is increasing more and more for industry each area.

Engine testing of ceramic cam-roller followers. Final report

Energy Technology Data Exchange (ETDEWEB)

Kalish, Y. [Detroit Diesel Corp., MI (United States)

1992-04-01

For several years, DDC has been developing monolithic ceramic heat engine components. One of the components, developed for an application in our state-of-the-art on-highway, heavy-duty diesel engine, the Series 60, is a silicon nitride cam-roller follower. Prior to starting this program, each valve train component in the Series 60 was considered for conversion to a ceramic material. Many advantages and disadvantages (benefits and risks) were considered. From this effort, one component was selected, the cam-roller follower. Using a system design approach, a ceramic cam-roller follower offered functional improvement at a reasonable cost. The purpose of the project was to inspect and test 100 domestically produced silicon nitride cam-roller followers built to the requirements of the DDC series 60 engine.

Temporal and spatial transcriptomic and microRNA dynamics of CAM photosynthesis in pineapple.

Science.gov (United States)

Wai, Ching M; VanBuren, Robert; Zhang, Jisen; Huang, Lixian; Miao, Wenjing; Edger, Patrick P; Yim, Won C; Priest, Henry D; Meyers, Blake C; Mockler, Todd; Smith, J Andrew C; Cushman, John C; Ming, Ray

2017-10-01

The altered carbon assimilation pathway of crassulacean acid metabolism (CAM) photosynthesis results in an up to 80% higher water-use efficiency than C 3 photosynthesis in plants making it a potentially useful pathway for engineering crop plants with improved drought tolerance. Here we surveyed detailed temporal (diel time course) and spatial (across a leaf gradient) gene and microRNA (miRNA) expression patterns in the obligate CAM plant pineapple [Ananas comosus (L.) Merr.]. The high-resolution transcriptome atlas allowed us to distinguish between CAM-related and non-CAM gene copies. A differential gene co-expression network across green and white leaf diel datasets identified genes with circadian oscillation, CAM-related functions, and source-sink relations. Gene co-expression clusters containing CAM pathway genes are enriched with clock-associated cis-elements, suggesting circadian regulation of CAM. About 20% of pineapple microRNAs have diel expression patterns, with several that target key CAM-related genes. Expression and physiology data provide a model for CAM-specific carbohydrate flux and long-distance hexose transport. Together these resources provide a list of candidate genes for targeted engineering of CAM into C 3 photosynthesis crop species. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

The Laser Guide Star System for Adaptive Optics at Subaru Telescope

Science.gov (United States)

Hayano, Y.; Saito, Y.; Ito, M.; Saito, N.; Akagawa, K.; Takazawa, A.; Ito, M.; Wada, S.; Takami, H.; Iye, M.

We report on the current status of developing the new laser guide star (LGS) system for the Subaru adaptive optics (AO) system. We have three major subsystems: the laser unit, the relay optical fiber and the laser launching telescope. A 4W-class all-solid-state 589nm laser has been developed as a light source for sodium laser guide star. We use two mode-locked Nd:YAG lasers operated at the wavelength of 1064nm and 1319nm to generate sum-frequency conversion into 589nm. The side-LD pumped configuration is used for the mode-locked Nd:YAG lasers. We have carefully considered the thermal lens effect in the cavity to achieve a high beam quality with TEM00; M2 = 1.06. The mode-locked frequency is selected at 143 MHz. We obtained the output powers of 16.5 W and 5.0 W at 1064nm and 1319 nm. Sum frequency generated by mixing two synchronized Nd:YAG mode-locked pulsed beams is precisely tuned to the sodium D2 line by thermal control of the etalon in the 1064nm Nd:YAG laser by observing the maximum fluorescence intensity of heated sodium vapor cell. The maximum output power at 589.159 nm reaches to 4.6 W using a PPMgOSLT crystal as a nonlinear optical crystal. And the output power can be maintained within a stability of +/- 1.2% for more than 3 days without optical damage. We developed a single-mode photonic crystal fiber (PCF) to relay the laser beam from laser clean room, in which the laser unit is located on the Nasmyth platform, to the laser launching telescope mounted behind the secondary mirror of Subaru Telescope. The photonic crystal fiber has solid pure silica core with the mode field diameter of 14 micron, which is relatively larger than that of the conventional step-index type single mode fiber. The length of the PCF is 35m and transmission loss due to the pure silica is 10dB/km at 589nm, which means PCF transmits 92% of the laser beam. We have preliminary achieved 75% throughput in total. Small mode-locked pulse width in time allows us to transmit the high

Predicting Visible Image Degradation by Colour Image Difference Formulae

Institute of Scientific and Technical Information of China (English)

Eriko Bando; Jon Y. Hardeberg; David Connah; Ivar Farup

2004-01-01

It carried out a CRT monitor based psychophysical experiment to investigate the quality of three colour image difference metrics, the CIEAE ab equation, the iCAM and the S-CIELAB metrics. Six original images were reproduced through six gamut mapping algorithms for the observer experiment. The result indicates that the colour image difference calculated by each metric does not directly relate to perceived image difference.

A review of complementary and alternative medicine (CAM) by people with multiple sclerosis.

Science.gov (United States)

Olsen, Sherri A

2009-01-01

Multiple sclerosis (MS) is a chronic, unpredictable disease of the central nervous system without a known cure. Because of this, people with MS often seek complementary and alternative medicines (CAM) to manage their disease symptoms. The goal of this review article was to describe the use of CAM by individuals diagnosed with MS. Evidence was obtained by searching Medline (1950-2007), EBSCOhost and PubMed for studies relating CAM to MS. Results from the literature showed that people with MS reported that they used CAM from 27 to 100%. The major reasons for choosing CAM were as follows: conventional treatment was not effective, anecdotal reports of CAM's help, and doctor referral. The types of CAM reported by people with MS included exercise, vitamins, herbal and mineral supplements, relaxation techniques, acupuncture, cannabis and massage. The major symptoms treated by CAM as noted in the literature were pain, fatigue and stress. There is a need for further research to evaluate the effectiveness of CAM with MS patients and their application by occupational therapists. The limitation of this literature review was the low response rate in many of the surveys reported. 2009 John Wiley & Sons, Ltd

Family medicine residency program directors attitudes and knowledge of family medicine CAM competencies.

Science.gov (United States)

Gardiner, Paula; Filippelli, Amanda C; Lebensohn, Patricia; Bonakdar, Robert

2013-01-01

Little is known about the incorporation of integrative medicine (IM) and complementary and alternative medicine (CAM) into family medicine residency programs. The Society for Teachers of Family Medicine (STFM) approved a set of CAM/IM competencies for family medicine residencies. We hope to evaluate whether residency programs are implementing such competencies into their curriculum using an online survey tool. We also hope to assess the knowledge and attitudes of Residency Directors (RDs) on the CAM/IM competencies. A survey was distributed by the Council of Academic Family Medicine (CAFM) Educational Research Alliance to RDs via e-mail. The survey was distributed to 431 RDs. Of those who received it, 212 responded, giving a response rate of 49.1%. Questions assessed the knowledge and attitudes of CAM/IM competencies and incorporation of CAM/IM into the residency curriculum. Forty-five percent of RDs were aware of the competencies. In terms of RD attitudes, 58% reported that CAM/IM is an important component of residents' curriculum; yet, 60% report not having specific learning objectives for CAM/IM in their residency curriculum. Among all programs, barriers to CAM/IM implementation included time in residents' schedules (77%); faculty training (75%); access to CAM experts (43%); lack of reimbursement (43%); and financial resources (29%). While many RDs are aware of the STFM CAM/IM competencies and acknowledge their role in residence education, there are many barriers that prevent residencies from implementing the STFM CAM/IM competencies. © 2013 Elsevier Inc. All rights reserved.

Integration of CAM and CNC operation through code editing and manipulation

International Nuclear Information System (INIS)

Rosli Darmawan; Shalina Sheik Muhammad

2004-01-01

The IT technology for engineering design and manufacturing has gone through significant advancement for the last 30 years. It is widely acknowledged that IT would provide competitive advantage for engineering company in term of production cycle, productivity and efficiency. The recent development in this area is on the total system integration. While standard off-shelf CAD/CAM/CNC software and hardware packages would provide solution for system integration, more often than not users will stumble upon compatibility problems. Moreover, most of the integration deals with CAD and CAM systems. CNC integration has not been fully developed. Users always found problems in the integration of CAM and CNC machine due to the different level of technological development. CNC codes have not fundamentally progressed in the last 50 years, while CAD/CAM software packages have undergone massive evolution and improvement. This paper discusses a practical solution of CAM and CNC integration through code editing and manipulation within the CAM system in order to comply with the CNC machine requirements. (Author)

Pattern and predictors of complementary and alternative medicine (CAM) use among pediatric patients with epilepsy.

Science.gov (United States)

Doering, Jan H; Reuner, Gitta; Kadish, Navah E; Pietz, Joachim; Schubert-Bast, Susanne

2013-10-01

Parents of pediatric patients with chronic conditions such as epilepsy increasingly opt for complementary and alternative medicine (CAM). However, data on the pattern and reasons of CAM use in childhood epilepsy are scarce. The objectives of this study were as follows: first, to characterize CAM use among pediatric patients with epilepsy by assessing its spectrum, prevalence, costs, and frequency of use; second, to evaluate the influence of CAM use on compliance and satisfaction with conventional care as well as to explore parent-child neurologist communication concerning CAM; and third, to investigate predictors of CAM use. A postal survey was administered to all parents of pediatric outpatients with epilepsy aged 6 to 12, who have received treatment at the neuropediatric outpatient clinic of the University Children's Hospital Heidelberg between 2007 and 2009. One hundred thirty-two of the 297 distributed questionnaires were suitable for inclusion in statistical analysis (44.7%). Forty-nine participants indicated that their children used CAM during the previous year (37.1%). Thirty different types of CAM were used, with homeopathy (55.1%), osteopathy (24.5%), and kinesiology (16.3%) being the most commonly named. A mean of 86€ (0€-500€) and 3h (1 h-30 h) per month was committed to CAM treatment. Only 53% of the users informed their child neurologist of the additional CAM treatment, while 85.6% of all parents wished to discuss CAM options with their child neurologist. Seventy-five percent of users considered the CAM treatment effective. Among the participants most likely to seek CAM treatment are parents whose children show a long duration of epileptic symptoms, parents who make use of CAM treatment themselves, and parents who value a holistic and natural treatment approach. A substantial portion of pediatric patients with epilepsy receive CAM treatment. The high prevalence of use and significant level of financial and time resources spent on CAM indicate the

Incorporation of CAD/CAM Restoration Into Navy Dentistry

Science.gov (United States)

2017-09-26

CAD/CAM Computer-aided design /Computer-assisted manufacturing CDT Common Dental Terminology DENCAS Dental Common Access System DTF Dental...to reduce avoidable dental emergencies for deployed sailors and marines. Dental Computer-aided design /Computer-assisted manufacturing (CAD/CAM...this time by allowing for rapid scanning, designing , development, and production of dental restorations. Using this technology gives dentists the

Experimentally induced cam impingement in the sheep hip.

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Siebenrock, Klaus A; Fiechter, Ruth; Tannast, Moritz; Mamisch, Tallal C; von Rechenberg, Brigitte

2013-04-01

Sheep hips have a natural non-spherical femoral head similar to a cam-type deformity in human beings. By performing an intertrochanteric varus osteotomy, cam-type femoro-acetabular impingement (FAI) during flexion can be created. We tested the hypotheses that macroscopic lesions of the articular cartilage and an increased Mankin score (MS) can be reproduced by an experimentally induced cam-type FAI in this ovine in vivo model. Furthermore, we hypothesized that the MS increases with longer ambulatory periods. Sixteen sheep underwent unilateral intertrochanteric varus osteotomy of the hip with the non-operated hip as a control. Four sheep were sacrificed after 14, 22, 30, and 38-weeks postoperatively. We evaluated macroscopic chondrolabral alterations, and recorded the MS, based on histochemical staining, for each ambulatory period. A significantly higher prevalence of macroscopic chondrolabral lesions was found in the impingement zone of the operated hips. The MS was significantly higher in the acetabular/femoral cartilage of the operated hips. Furthermore, these scores increased as the length of the ambulatory period increased. Cam-type FAI can be induced in an ovine in vivo model. Localized chondrolabral degeneration of the hip, similar to that seen in humans (Tannast et al., Clin Orthop Relat Res 2008; 466: 273-280; Beck et al., J Bone Joint Surg Br 2005; 87: 1012-1018), can be reproduced. This experimental sheep model can be used to study cam-type FAI. Copyright © 2012 Orthopaedic Research Society.

Sex Differences in Patients With CAM Deformities With Femoroacetabular Impingement: 3-Dimensional Computed Tomographic Quantification.

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Yanke, Adam B; Khair, M Michael; Stanley, Robert; Walton, David; Lee, Simon; Bush-Joseph, Charles A; Espinoza Orías, Alejandro; Espinosa Orias, Alejandro A; Inoue, Nozomu; Nho, Shane J

2015-12-01

To determine if significant differences exist between male and female CAM deformities using quantitative 3-dimensional (3D) volume and location analysis. Retrospective analysis of preoperative computed tomographic (CT) scans for 138 femurs (69 from male patients and 69 from female patients) diagnosed with impingement from November 2009 to November 2011 was completed. Those patients who presented with hip complaints and had a history, physical examination (limited range of motion, positive impingement signs), plain radiographs (anteroposterior pelvis, 90° Dunn view, false profile view), and magnetic resonance images consistent with femoroacetabular impingement (FAI) and in whom a minimum of 6 months of conservative therapy (oral anti-inflammatory agents, physical therapy, and activity modification) had failed were indicated for arthroscopic surgery and had a preoperative CT scan. Scans were segmented, converted to point cloud data, and analyzed with a custom-written computer program. Analysis included mean CAM height and volume, head radius, and femoral version. Differences were analyzed using an unpaired t test with significance set at P position ± the 2:51 o'clock position to the 3:28 o'clock position ± the 1:59 o'clock position, with an average span from the 3:06 o'clock position ± the 1:29 o'clock position (male patients, the 11:23 o'clock position ± the 0:46 o'clock position to the 3:05 o'clock position ± the 1:20 o'clock position; female patients, the 11:33 o'clock position ± the 0:37 o'clock position to the 2:27 o'clock position ± the 0:45 o'clock position). There were no differences in the posterior (P = .60) or anterior (P = .14) extent of CAM deformities. However, the span on the clock face of the CAM deformities varied when comparing men with women (male patients, the 3:43 o'clock position ± the 1:29 o'clock position; female patients, the 2:54 o'clock position ± the 1:09 o'clock position; P = .02). Our data show that female CAM deformities

Optimising the cam profile of an electronic unit pump for a heavy-duty diesel engine

International Nuclear Information System (INIS)

Qiu, Tao; Dai, Hefei; Lei, Yan; Cao, Chunlei; Li, Xuchu

2015-01-01

For a fuel system with a tangent cam or a constant-velocity cam, the peak injection pressure continues to rise as the injection duration increases, but overly high peak pressures induce mechanical loads and wear, limiting the maximum engine speed and injection quantity. To improve the performance of an EUP (Electronic Unit Pump) fuel system for heavy-duty diesel engines, this work proposes a new pump cam, namely the constant-pressure cam. It helps the EUP run at a higher speed and deliver larger fuel quantities while maintaining a constant peak injection pressure, which improves the power of the heavy-duty diesel engine. A model based on the EUP was built to determine the three constraints for optimising the constant-pressure cam: 1) the pump pressure should equal the nozzle pressure; 2) the cam speed should decrease with the increase in the injection duration; and 3) the cam acceleration gradient should be zero. An EUP system was tested with the tangent cam and the optimised cam under different conditions. The experimental results show that the EUP system with the optimised cam delivers more injection quantity and runs at higher engine speeds while maintaining the same peak pressure as the tangent cam. - Highlights: • We propose a constant-pressure cam to improve the power of heavy-duty diesel engine. • We deduce three constraints for the CP (constant-peak pressure) cam based on a model. • The EUP system with the new cam works well under higher engine speed. • The peak pressure of the constant-pressure cam fuel system maintains high

Fiber-optical switch using cam-micromotor driven by scratch drive actuators

Science.gov (United States)

Kanamori, Y.; Aoki, Y.; Sasaki, M.; Hosoya, H.; Wada, A.; Hane, K.

2005-01-01

We fabricated a 1 × 1 fiber-optic switch using a cam-micromotor driven by scratch drive actuators (SDAs). Using the cam-micromotor, mechanical translation and precise positioning of an optical fiber were performed. An optical fiber of diameter 50 µm was bent and pushed out with a cam-mechanism driven by the SDAs fabricated by surface micromachining. The maximum rotation speed of the cam-micromotor was 7.5 rpm at a driving frequency of 1.5 kHz. The transient time of the switch to attenuate coupling efficiency less than -40 dB was around 10 ms.

A MegaCam Survey of Outer Halo Satellites. I. Description of the Survey

Science.gov (United States)

Muñoz, Ricardo R.; Côté, Patrick; Santana, Felipe A.; Geha, Marla; Simon, Joshua D.; Oyarzún, Grecco A.; Stetson, Peter B.; Djorgovski, S. G.

2018-06-01

We describe a deep, systematic imaging study of satellites in the outer halo of the Milky Way. Our sample consists of 58 stellar overdensities—i.e., substructures classified as either globular clusters, classical dwarf galaxies, or ultra-faint dwarf galaxies—that are located at Galactocentric distances of R GC ≥ 25 kpc (outer halo) and out to ∼400 kpc. This includes 44 objects for which we have acquired deep, wide-field, g- and r-band imaging with the MegaCam mosaic cameras on the 3.6 m Canada–France–Hawaii Telescope and the 6.5 m Magellan-Clay telescope. These data are supplemented by archival imaging, or published gr photometry, for an additional 14 objects, most of which were discovered recently in the Dark Energy Survey (DES). We describe the scientific motivation for our survey, including sample selection, observing strategy, data reduction pipeline, calibration procedures, and the depth and precision of the photometry. The typical 5σ point-source limiting magnitudes for our MegaCam imaging—which collectively covers an area of ≈52 deg2—are g lim ≃ 25.6 and r lim ≃ 25.3 AB mag. These limits are comparable to those from the coadded DES images and are roughly a half-magnitude deeper than will be reached in a single visit with the Large Synoptic Survey Telescope. Our photometric catalog thus provides the deepest and most uniform photometric database of Milky Way satellites available for the foreseeable future. In other papers in this series, we have used these data to explore the blue straggler populations in these objects, their density distributions, star formation histories, scaling relations, and possible foreground structures.

Exploring the Potential of a Wearable Camera to Examine the Early Obesogenic Home Environment: Comparison of SenseCam Images to the Home Environment Interview.

Science.gov (United States)

Schrempft, Stephanie; van Jaarsveld, Cornelia Hm; Fisher, Abigail

2017-10-12

The obesogenic home environment is usually examined via self-report, and objective measures are required. This study explored whether the wearable camera SenseCam can be used to examine the early obesogenic home environment and whether it is useful for validation of self-report measures. A total of 15 primary caregivers of young children (mean age of child 4 years) completed the Home Environment Interview (HEI). Around 12 days after the HEI, participants wore the SenseCam at home for 4 days. A semistructured interview assessed participants' experience of wearing the SenseCam. Intraclass correlation coefficients (ICCs), percent agreement, and kappa statistics were used as validity estimates for 54 home environment features. Wearing the SenseCam was generally acceptable to those who participated. The SenseCam captured all 54 HEI features but with varying detail; 36 features (67%) had satisfactory validity (ICC or kappa ≥0.40; percent agreement ≥80 where kappa could not be calculated). Validity was good or excellent (ICC or kappa ≥0.60) for fresh fruit and vegetable availability, fresh vegetable variety, display of food and drink (except sweet snacks), family meals, child eating lunch or dinner while watching TV, garden and play equipment, the number of TVs and DVD players, and media equipment in the child's bedroom. Validity was poor (ICC or kappa Internet Research (http://www.jmir.org), 12.10.2017.

Evaluation of complementary-alternative medicine (CAM) questionnaire development for Indonesian clinical psychologists: A pilot study.

Science.gov (United States)

Liem, Andrian; Newcombe, Peter A; Pohlman, Annie

2017-08-01

This study aimed to evaluate questionnaire development to measure the knowledge of Complementary-Alternative Medicine (CAM), attitudes towards CAM, CAM experiences, and CAM educational needs of clinical psychologists in Indonesia. A 26-item questionnaire was developed through an extensive literature search. Data was obtained from provisional psychologists from the Master of Professional Clinical Psychology programs at two established public universities in urban areas of Indonesia. To validate the questionnaire, panel reviews by executive members of the Indonesian Clinical Psychology Association (ICPA), experts in health psychology, and experts in public health and CAM provided their professional judgements. The self-reporting questionnaire consisted of four scales including: knowledge of CAM (6 items), attitudes towards CAM (10 items), CAM experiences (4 items), and CAM educational needs (6 items). All scales, except CAM Experiences, were assessed on a 7-point Likert scale. Sixty provisional psychologists were eligible to complete the questionnaire with a response rate of 73% (N=44). The results showed that the CAM questionnaire was reliable (Cronbach's coefficient alpha range=0.62-0.96; item-total correlation range=0.14-0.92) and demonstrated content validity. Following further psychometric evaluation, the CAM questionnaire may provide the evidence-based information to inform the education and practice of Indonesian clinical psychologists. Copyright © 2017 Elsevier Ltd. All rights reserved.

Examination of a high resolution laser optical plankton counter and FlowCAM for measuring plankton concentration and size

Science.gov (United States)

Kydd, Jocelyn; Rajakaruna, Harshana; Briski, Elizabeta; Bailey, Sarah

2018-03-01

Many commercial ships will soon begin to use treatment systems to manage their ballast water and reduce the global transfer of harmful aquatic organisms and pathogens in accordance with upcoming International Maritime Organization regulations. As a result, rapid and accurate automated methods will be needed to monitoring compliance of ships' ballast water. We examined two automated particle counters for monitoring organisms ≥ 50 μm in minimum dimension: a High Resolution Laser Optical Plankton Counter (HR-LOPC), and a Flow Cytometer with digital imaging Microscope (FlowCAM), in comparison to traditional (manual) microscopy considering plankton concentration, size frequency distributions and particle size measurements. The automated tools tended to underestimate particle concentration compared to standard microscopy, but gave similar results in terms of relative abundance of individual taxa. For most taxa, particle size measurements generated by FlowCAM ABD (Area Based Diameter) were more similar to microscope measurements than were those by FlowCAM ESD (Equivalent Spherical Diameter), though there was a mismatch in size estimates for some organisms between the FlowCAM ABD and microscope due to orientation and complex morphology. When a single problematic taxon is very abundant, the resulting size frequency distribution curves can become skewed, as was observed with Asterionella in this study. In particular, special consideration is needed when utilizing automated tools to analyse samples containing colonial species. Re-analysis of the size frequency distributions with the removal of Asterionella from FlowCAM and microscope data resulted in more similar curves across methods with FlowCAM ABD having the best fit compared to the microscope, although microscope concentration estimates were still significantly higher than estimates from the other methods. The results of our study indicate that both automated tools can generate frequency distributions of particles

Demand for CAM Practice at Hospitals in Japan: A Population Survey in Mie Prefecture

Directory of Open Access Journals (Sweden)

Toshihiro Togo

2011-01-01

Full Text Available Complementary and alternative medicine (CAM therapies have been provided at hospitals along with conventional medicine in industrialized nations. Previous studies conducted in Japan revealed high proportion of Japanese had experience of using CAM, but failed to discuss how it should be provided. The present study aims to clarify the demand for CAM practice at hospitals in Japan. A questionnaire consisting of 41 questions was mailed to 10 000 adults randomly selected from the electoral roll of Mie prefecture, Japan in January 2007. The questionnaire asked the subjects about demand for CAM practice at hospitals, types of CAM therapy to be provided and associated reasons. Sociodemographic characteristics, perceived health status, experience and purpose of CAM use, and information resource for CAM were also surveyed. Completed answers were collected from 2824 (28.6% respondents. Two thousand and nineteen (71.5% of the respondents demanded CAM practice at hospitals with the most likely reason of “patients can receive treatment under the guidance of a physicians”. The three most popular CAM therapies were Kampo, acupressure/massage/Shiatsu and acupuncture/moxibustion. The demand was positively associated with gender, ages of 40–59 years, annual household incomes of 5–7 million yen, occupation of specialist and technical workers and sales workers and poor health status. Higher demand was observed among those who used both CAM and conventional medical therapies for curative purposes. In conclusion, Japanese show a high demand for CAM practice, hoping to use CAM for curative purposes with monitoring by physicians at hospitals.

Evolution of CAM and C4 carbon-concentrating mechanisms

Science.gov (United States)

Keeley, Jon E.; Rundel, Philip W.

2003-01-01

Mechanisms for concentrating carbon around the Rubisco enzyme, which drives the carbon-reducing steps in photosynthesis, are widespread in plants; in vascular plants they are known as crassulacean acid metabolism (CAM) and C4 photosynthesis. CAM is common in desert succulents, tropical epiphytes, and aquatic plants and is characterized by nighttime fixation of CO2. The proximal selective factor driving the evolution of this CO2-concentrating pathway is low daytime CO2, which results from the unusual reverse stomatal behavior of terrestrial CAM species or from patterns of ambient CO2 availability for aquatic CAM species. In terrestrials the ultimate selective factor is water stress that has selected for increased water use efficiency. In aquatics the ultimate selective factor is diel fluctuations in CO2 availability for palustrine species and extreme oligotrophic conditions for lacustrine species. C4 photosynthesis is based on similar biochemistry but carboxylation steps are spatially separated in the leaf rather than temporally as in CAM. This biochemical pathway is most commonly associated with a specialized leaf anatomy known as Kranz anatomy; however, there are exceptions. The ultimate selective factor driving the evolution of this pathway is excessively high photorespiration that inhibits normal C3 photosynthesis under high light and high temperature in both terrestrial and aquatic habitats. CAM is an ancient pathway that likely has been present since the Paleozoic era in aquatic species from shallow-water palustrine habitats. While atmospheric CO2 levels have undoubtedly affected the evolution of terrestrial plant carbon-concentrating mechanisms, there is reason to believe that past atmospheric changes have not played as important a selective role in the aquatic milieu since palustrine habitats today are not generally carbon sinks, and the selective factors driving aquatic CAM are autogenic. Terrestrial CAM, in contrast, is of increasing selective value under

Fracture strength testing of crowns made of CAD/CAM composite resins.

Science.gov (United States)

Okada, Ryota; Asakura, Masaki; Ando, Akihiro; Kumano, Hirokazu; Ban, Seiji; Kawai, Tatsushi; Takebe, Jun

2018-03-28

The purpose of this study was to ascertain whether computer aided design/computer aided manufacturing (CAD/CAM) composite resin crowns have sufficient strength to withstand the bite force of the molar teeth. The null hypothesis was that the fracture strength of CAD/CAM composite resin crowns is lower than the average maximum bite force of the molar tooth. The crowns, which shape is the right maxillary first molar, were fabricated using four CAD/CAM blanks made of composite resins (Block HC: HC, KZR-CAD HR: HR, KZR-CAD HR2: HR2, Avencia Block: AVE) and one CAD/CAM blank made of lithium disilicate glass-ceramic (IPS e.max CAD: IPS), which was used as a control. Fracture strength of fabricated crowns bonded to metal abutment and biaxial flexural strength of the materials were evaluated. The results of fracture strength test and biaxial flexural strength test showed different tendencies. The fracture strength of CAD/CAM composite resin crowns except HC ranged from 3.3kN to 3.9kN, and was similar to that of IPS (3.3kN). In contrast, biaxial flexural strength of CAD/CAM composite resins ranged from 175MPa to 247MPa, and was significantly lower than that of IPS (360MPa). All CAD/CAM composite resin crowns studied presented about 3-4 times higher fracture strength than the average maximum bite force of the molar tooth (700-900N), which result leads to the conclusion that CAD/CAM composite resin crowns would have sufficient strength to withstand the bite force of the molar teeth. Copyright © 2017 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

Reasons for continuing use of Complementary and Alternative Medicine (CAM) in students: a consumer commitment model.

Science.gov (United States)

Sirois, Fuschia M; Salamonsen, Anita; Kristoffersen, Agnete E

2016-02-24

Research on continued CAM use has been largely atheoretical and has not considered the broader range of psychological and behavioral factors that may be involved. The purpose of this study was to test a new conceptual model of commitment to CAM use that implicates utilitarian (trust in CAM) and symbolic (perceived fit with CAM) in psychological and behavioral dimensions of CAM commitment. A student sample of CAM consumers, (N = 159) completed a survey about their CAM use, CAM-related values, intentions for future CAM use, CAM word-of-mouth behavior, and perceptions of being an ongoing CAM consumer. Analysis revealed that the utilitarian, symbolic, and CAM commitment variables were significantly related, with r's ranging from .54 to .73. A series hierarchical regression analyses controlling for relevant demographic variables found that the utilitarian and symbolic values uniquely accounted for significant and substantial proportion of the variance in each of the three CAM commitment indicators (R(2) from .37 to .57). The findings provide preliminary support for the new model that posits that CAM commitment is a multi-dimensional psychological state with behavioral indicators. Further research with large-scale samples and longitudinal designs is warranted to understand the potential value of the new model.

Bonding Effectiveness of Luting Composites to Different CAD/CAM Materials.

Science.gov (United States)

Peumans, Marleen; Valjakova, Emilija Bajraktarova; De Munck, Jan; Mishevska, Cece Bajraktarova; Van Meerbeek, Bart

To evaluate the influence of different surface treatments of six novel CAD/CAM materials on the bonding effectiveness of two luting composites. Six different CAD/CAM materials were tested: four ceramics - Vita Mark II; IPS Empress CAD and IPS e.max CAD; Celtra Duo - one hybrid ceramic, Vita Enamic, and one composite CAD/CAM block, Lava Ultimate. A total of 60 blocks (10 per material) received various mechanical surface treatments: 1. 600-grit SiC paper; 2. sandblasting with 30-μm Al2O3; 3. tribochemical silica coating (CoJet). Subsequent chemical surface treatments involved either no further treatment (control), HF acid etching (HF), silanization (S, or HF acid etching followed by silanization (HF+S). Two specimens with the same surface treatment were bonded together using two dual-curing luting composites: Clearfil Esthetic Cement (self-etching) or Panavia SA Cement (self-adhesive). After 1 week of water storage, the microtensile bond strength of the sectioned microspecimens was measured and the failure mode was evaluated. The bonding performance of the six CAD/CAM materials was significantly influenced by surface treatment (linear mixed models, p CAD (p = 0.0115), and Lava Ultimate (p CAD/CAM materials: Vita Mark II and IPS Empress CAD: S, HF+S; Celtra Duo: HF, HF+S; IPS e.max CAD: HF+S; Vita Enamic: HF+S, S. For Lava Ultimate, the highest bond strengths were obtained with HF, S, HF+S. Failure analysis showed a relation between bond strength and failure type: more mixed failures were observed with higher bond strengths. Mainly adhesive failures were noticed if no further surface treatment was done. The percentage of adhesive failures was higher for CAD/CAM materials with higher flexural strength (Celtra Duo, IPS e.max CAD, and Lava Ultimate). The bond strength of luting composites to novel CAD/CAM materials is influenced by surface treatment. For each luting composite, an adhesive cementation protocol can be specified in order to obtain the highest bond to the

Effectiveness and efficiency of a CAD/CAM orthodontic bracket system.

Science.gov (United States)

Brown, Matthew W; Koroluk, Lorne; Ko, Ching-Chang; Zhang, Kai; Chen, Mengqi; Nguyen, Tung

2015-12-01

The first straight-wire appliance was introduced over 40 years ago to increase the consistency and efficiency of orthodontic treatment. More recently, computer-aided design and computer-aided manufacturing (CAD/CAM) technology has been used to create individualized orthodontic appliances. The purpose of this study was to investigate the clinical effectiveness and efficiency of CAD/CAM customized orthodontic appliances compared with direct and indirect bonded stock orthodontic brackets. This retrospective study included 3 treatment groups: group 1 patients were direct bonded with self-ligating appliances, group 2 patients were indirect bonded with self-ligating appliances, and group 3 patients were indirect bonded with CAD/CAM self-ligating appliances. Complete pretreatment and posttreatment records were obtained for all patients. The American Board of Orthodontics (ABO) Discrepancy Index was used to evaluate the pretreatment records, and the posttreatment outcomes were analyzed using the ABO Cast-Radiograph Evaluation. All data collection and analysis were completed by 1 evaluator. There were no statistically significant differences in the ABO Discrepancy Index or the ABO Cast-Radiograph Evaluation among the groups. Treatment times for the 3 groups were significantly different; the CAD/CAM group was the shortest at 13.8 ± 3.4 months, compared with 21.9 ± 5.0 and 16.9 ± 4.1 months for the direct bonded and indirect bonded groups, respectively. The number of treatment appointments for the CAD/CAM group was significantly fewer than for the direct bonded group. The CAD/CAM orthodontic bracket system evaluated in this study was as effective in treatment outcome measures as were standard brackets bonded both directly and indirectly. The CAD/CAM appliance was more efficient in regard to treatment duration, although the decrease in total archwire appointments was minimal. Further investigation is needed to better quantify the clinical benefits of CAD/CAM orthodontic

DIRECT IMAGING CONFIRMATION AND CHARACTERIZATION OF A DUST-ENSHROUDED CANDIDATE EXOPLANET ORBITING FOMALHAUT

International Nuclear Information System (INIS)

Currie, Thayne; Debes, John; Rodigas, Timothy J.; Burrows, Adam; Itoh, Yoichi; Fukagawa, Misato; Kenyon, Scott J.; Kuchner, Marc; Matsumura, Soko

2012-01-01

We present Subaru/IRCS J-band data for Fomalhaut and a (re)reduction of archival 2004-2006 HST/ACS data first presented by Kalas et al. We confirm the existence of a candidate exoplanet, Fomalhaut b, in both the 2004 and 2006 F606W data sets at a high signal-to-noise ratio. Additionally, we confirm the detection at F814W and present a new detection in F435W. Fomalhaut b's space motion may be consistent with it being in an apsidally aligned, non-debris ring-crossing orbit, although new astrometry is required for firmer conclusions. We cannot confirm that Fomalhaut b exhibits 0.7-0.8 mag variability cited as evidence for planet accretion or a semi-transient dust cloud. The new, combined optical spectral energy distribution and IR upper limits confirm that emission identifying Fomalhaut b originates from starlight scattered by small dust, but this dust is most likely associated with a massive body. The Subaru and IRAC/4.5 μm upper limits imply M J , still consistent with the range of Fomalhaut b masses needed to sculpt the disk. Fomalhaut b is very plausibly 'a planet identified from direct imaging' even if current images of it do not, strictly speaking, show thermal emission from a directly imaged planet.

CAM and stack air sampler design guide

International Nuclear Information System (INIS)

Phillips, T.D.

1994-01-01

About 128 air samplers and CAMs presently in service to detect and document potential radioactive release from 'H' and 'F' area tank farm ventilation stacks are scheduled for replacement and/or upgrade by Projects S-5764, S-2081, S-3603, and S-4516. The seven CAMs scheduled to be upgraded by Project S-4516 during 1995 are expected to provide valuable experience for the three remaining projects. The attached document provides design guidance for the standardized High Level Waste air sampling system

Verification of Kaplan turbine cam curves realization accuracy at power plant

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Džepčeski Dane

2016-01-01

Full Text Available Sustainability of approximately constant value of Kaplan turbine efficiency, for relatively large net head changes, is a result of turbine runner variable geometry. Dependence of runner blades position change on guide vane opening represents the turbine cam curve. The cam curve realization accuracy is of great importance for the efficient and proper exploitation of turbines and consequently complete units. Due to the reasons mentioned above, special attention has been given to the tests designed for cam curves verification. The goal of this paper is to provide the description of the methodology and the results of the tests performed in the process of Kaplan turbine cam curves verification.

CAM use in pediatric neurology: an exploration of concurrent use with conventional medicine.

Science.gov (United States)

Galicia-Connolly, Elaine; Adams, Denise; Bateman, Justin; Dagenais, Simon; Clifford, Tammy; Baydala, Lola; King, W James; Vohra, Sunita

2014-01-01

Previous studies have found that up to 60% of children with neurologic conditions have tried complementary and alternative medicine (CAM). To assess the use of CAM among patients presenting to neurology clinics at two academic centers in Canada. A survey instrument was developed to inquire about use of CAM products and therapies, including reasons for use, perceived helpfulness, and concurrent use with conventional medicine, and administered to patients or their parents/guardians at the Stollery Children's Hospital in Edmonton and the Children's Hospital of Eastern Ontario (CHEO) in Ottawa. Overall CAM use at the Stollery was 78%, compared to 48% at CHEO. The most common CAM products used were multi-vitamins (84%), vitamin C (37%), homeopathic remedies (24%), and fish oil/omega 3 s (22%). The most common CAM practices used were massage (47%), chiropractic (37%), faith healing (18%), aromatherapy (16%), homeopathy (16%), and relaxation (16%). Many patients used CAM products at the same time as conventional medicine but just over half (57%) discussed this concurrent use with their physician. CAM use is common in pediatric neurology patients and most respondents felt that it was helpful, with few or no harms associated. However, this use is often undisclosed, increasing possibility of interactions with conventional drugs. We urge clinicians to inquire about CAM use during routine history taking at every patient visit. Parents would clearly like more information about CAM from their specialty clinics; such information would be easier to share if more primary data were available about the safety and effectiveness of commonly used therapies.

Prevalence of cam hip shape morphology: a systematic review.

Science.gov (United States)

Dickenson, E; Wall, P D H; Robinson, B; Fernandez, M; Parsons, H; Buchbinder, R; Griffin, D R

2016-06-01

Cam hip shape morphology is a recognised cause of femoroacetabular impingement (FAI) and is associated with hip osteoarthritis. Our aim was to systematically review the available epidemiological evidence assessing the prevalence of cam hip shape morphology in the general population and any studied subgroups including subjects with and without hip pain. All studies that reported the prevalence of cam morphology, measured by alpha angles, in subjects aged 18 and over, irrespective of study population or presence of hip symptoms were considered for inclusion. We searched AMED, MEDLINE, EMBASE, CINAHL and CENTRAL in October 2015. Two authors independently identified eligible studies and assessed risk of bias. We planned to pool data of studies considered clinically homogenous. Thirty studies met inclusion criteria. None of the included studies were truly population-based: three included non-representative subgroups of the general population, 19 included differing clinical populations, while eight included professional athletes. All studies were judged to be at high risk of bias. Due to substantial clinical heterogeneity meta analysis was not possible. Across all studies, the prevalence estimates of cam morphology ranged from 5 to 75% of participants affected. We were unable to demonstrate a higher prevalence in selected subgroups such as athletes or those with hip pain. There is currently insufficient high quality data to determine the true prevalence of cam morphology in the general population or selected subgroups. Well-designed population-based epidemiological studies that use homogenous case definitions are required to determine the prevalence of cam morphology and its relationship to hip pain. Copyright © 2016 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

CAM therapies among primary care patients using opioid therapy for chronic pain

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Mundt Marlon P

2007-05-01

Full Text Available Abstract Background Complementary and alternative medicine (CAM is an increasingly common therapy used to treat chronic pain syndromes. However; there is limited information on the utilization and efficacy of CAM therapy in primary care patients receiving long-term opioid therapy. Method A survey of CAM therapy was conducted with a systematic sample of 908 primary care patients receiving opioids as a primary treatment method for chronic pain. Subjects completed a questionnaire designed to assess utilization, efficacy and costs of CAM therapies in this population. Results Patients were treated for a variety of pain problems including low back pain (38.4%, headaches (9.9%, and knee pain (6.5%; the average duration of pain was 16 years. The median morphine equivalent opioid dose was 41 mg/day, and the mean dose was 92 mg/day. Forty-four percent of the sample reported CAM therapy use in the past 12 months. Therapies utilized included massage therapy (27.3%, n = 248, chiropractic treatment (17.8%, n = 162, acupuncture (7.6%, n = 69, yoga (6.1%, n = 55, herbs and supplements (6.8%, n = 62, and prolotherapy (5.9%, n = 54. CAM utilization was significantly related to age female gender, pain severity income pain diagnosis of neck and upper back pain, and illicit drug use. Medical insurance covered chiropractic treatment (81.8% and prolotherapy (87.7%, whereas patients primarily paid for other CAM therapies. Over half the sample reported that one or more of the CAM therapies were helpful. Conclusion This study suggests CAM therapy is widely used by patients receiving opioids for chronic pain. Whether opioids can be reduced by introducing such therapies remains to be studied.

CAM therapies among primary care patients using opioid therapy for chronic pain.

Science.gov (United States)

Fleming, Sara; Rabago, David P; Mundt, Marlon P; Fleming, Michael F

2007-05-16

Complementary and alternative medicine (CAM) is an increasingly common therapy used to treat chronic pain syndromes. However; there is limited information on the utilization and efficacy of CAM therapy in primary care patients receiving long-term opioid therapy. A survey of CAM therapy was conducted with a systematic sample of 908 primary care patients receiving opioids as a primary treatment method for chronic pain. Subjects completed a questionnaire designed to assess utilization, efficacy and costs of CAM therapies in this population. Patients were treated for a variety of pain problems including low back pain (38.4%), headaches (9.9%), and knee pain (6.5%); the average duration of pain was 16 years. The median morphine equivalent opioid dose was 41 mg/day, and the mean dose was 92 mg/day. Forty-four percent of the sample reported CAM therapy use in the past 12 months. Therapies utilized included massage therapy (27.3%, n = 248), chiropractic treatment (17.8%, n = 162), acupuncture (7.6%, n = 69), yoga (6.1%, n = 55), herbs and supplements (6.8%, n = 62), and prolotherapy (5.9%, n = 54). CAM utilization was significantly related to age female gender, pain severity income pain diagnosis of neck and upper back pain, and illicit drug use. Medical insurance covered chiropractic treatment (81.8%) and prolotherapy (87.7%), whereas patients primarily paid for other CAM therapies. Over half the sample reported that one or more of the CAM therapies were helpful. This study suggests CAM therapy is widely used by patients receiving opioids for chronic pain. Whether opioids can be reduced by introducing such therapies remains to be studied.

Valve cam design using numerical step-by-step method

OpenAIRE

Vasilyev, Aleksandr; Bakhracheva, Yuliya; Kabore, Ousman; Zelenskiy, Yuriy

2014-01-01

This article studies the numerical step-by-step method of cam profile design. The results of the study are used for designing the internal combustion engine valve gear. This method allows to profile the peak efficiency of cams in view of many restrictions, connected with valve gear serviceability and reliability.

A Prospective, Multicenter Study of Complementary/Alternative Medicine (CAM) Utilization During Definitive Radiation for Breast Cancer

International Nuclear Information System (INIS)

Moran, Meena S.; Ma Shuangge; Jagsi, Reshma; Yang, Tzu-I Jonathan; Higgins, Susan A.; Weidhaas, Joanne B.; Wilson, Lynn D.; Lloyd, Shane; Peschel, Richard; Gaudreau, Bryant; Rockwell, Sara

2013-01-01

Purpose: Although complementary and alternative medicine (CAM) utilization in breast cancer patients is reported to be high, there are few data on CAM practices in breast patients specifically during radiation. This prospective, multi-institutional study was conducted to define CAM utilization in breast cancer during definitive radiation. Materials/Methods: A validated CAM instrument with a self-skin assessment was administered to 360 Stage 0-III breast cancer patients from 5 centers during the last week of radiation. All data were analyzed to detect significant differences between users/nonusers. Results: CAM usage was reported in 54% of the study cohort (n=194/360). Of CAM users, 71% reported activity-based CAM (eg, Reiki, meditation), 26% topical CAM, and 45% oral CAM. Only 16% received advice/counseling from naturopathic/homeopathic/medical professionals before initiating CAM. CAM use significantly correlated with higher education level (P<.001), inversely correlated with concomitant hormone/radiation therapy use (P=.010), with a trend toward greater use in younger patients (P=.066). On multivariate analysis, level of education (OR: 6.821, 95% CI: 2.307-20.168, P<.001) and hormones/radiation therapy (OR: 0.573, 95% CI: 0.347-0.949, P=.031) independently predicted for CAM use. Significantly lower skin toxicity scores were reported in CAM users vs nonusers, respectively (mild: 34% vs 25%, severe: 17% vs 29%, P=.017). Conclusion: This is the first prospective study to assess CAM practices in breast patients during radiation, with definition of these practices as the first step for future investigation of CAM/radiation interactions. These results should alert radiation oncologists that a large percentage of breast cancer patients use CAM during radiation without disclosure or consideration for potential interactions, and should encourage increased awareness, communication, and documentation of CAM practices in patients undergoing radiation treatment for breast

AFSC/FMA/CAMS Data Objects

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The CAMS system consists of a set of tables and packages that provide authentication services to all other North Pacific Groundfish and Halibut Observing Program...

Ceramic dental biomaterials and CAD/CAM technology: state of the art.

Science.gov (United States)

Li, Raymond Wai Kim; Chow, Tak Wah; Matinlinna, Jukka Pekka

2014-10-01

Ceramics are widely used as indirect restorative materials in dentistry because of their high biocompatibility and pleasing aesthetics. The objective is to review the state of the arts of CAD/CAM all-ceramic biomaterials. CAD/CAM all-ceramic biomaterials are highlighted and a subsequent literature search was conducted for the relevant subjects using PubMed followed by manual search. Developments in CAD/CAM technology have catalyzed researches in all-ceramic biomaterials and their applications. Feldspathic glass ceramic and glass infiltrated ceramic can be fabricated by traditional laboratory methods or CAD/CAM. The advent of polycrystalline ceramics is a direct result of CAD/CAM technology without which the fabrication would not have been possible. The clinical uses of these ceramics have met with variable clinical success. Multiple options are now available to the clinicians for the fabrication of aesthetic all ceramic restorations. Copyright © 2014 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

CAD/CAM: improved design quality, increased productivity

Energy Technology Data Exchange (ETDEWEB)

Evans, D. E.; England, J.

1980-01-01

Maintaining productivity levels while assuring the quality of engineering products grows increasingly more difficult and costly for industries such as the energy industry which are heavily committed to product design. The man/machine interface made possible through the development of computer-aided design/computer-aided manufacturing (CAD/CAM) technology can be applied to the design process as a tool for increased control to assure the quality of the final engineering product. The quality-control aspects of CAD/CAM technology are addressed in this presentation.

Jupiter's Great Red Spot upper cloud morphology and dynamics from JunoCam images

Science.gov (United States)

Sanchez-Lavega, A.; Hueso, R.; Eichstädt, G.; Orton, G.; Rogers, J.; Hansen, C. J.; Momary, T.; Tabataba-Vakili, F.

2017-12-01

We present an analysis of RGB color-composite images of the Great Red Spot (GRS) obtained with JunoCam during Juno's seventh close flyby (PJ7) on July 11, 2017. The images have been projected as 4 cylindrical maps with a resolution of 180 pixels per degree (about 7 km/pixel) spanning a temporal interval of 9 min 41s. The GRS shows a rich variety of cloud morphologies that reveal different dynamical processes in its interior. We consider three major regions. (1) An outer peripheral ring of homogeneous reddish clouds (width about 1,300 km) traces a laminar flow. A family of at least three packets of gravity waves with a mean wavelength of 75 km is present at the internal edge of the ring (in its northern side). They occupy an area of 2,500 km in length (East-West, EW) and 670 km in the North-South (NS) direction. Single clouds in the groups forming the wave have extents of 35 km EW and 70-135 km NS. (2) A large internal region of red clouds (width about 3,200 km) contains three morphologies: (a) fields of bright cumulus-like clusters, (b) long, dark curved filaments (about 7,000 km length with 100 km width), two of them converging into an arrowhead shape, and (c) individual anticyclonic vortices with radius of 500 km that grow due to the radial shear of the wind velocity in the GRS interior as previously measured. A cumulus cluster is conspicuous inside one such anticyclone. Each single cloud element is 50 km in size and the cluster has a 25-30 percent area coverage in cumulus-convective activity, presumably due to ammonia moist convection. (3) A central core has quasi-rectangular shape, extending about 5000 km EW and 3000 km NS, that is confined by elongated clouds distributed along its periphery. Its interior is filled with the redder clouds in the GRS that have a scale 100 km and form a turbulent pattern whose cloud orientations suggest three adjacent areas with alternating cyclonic-cyclonic-anticyclonic vorticity, each with radius 650-850 km.

Usability of Calibrating Monitor for Soft Proof According to CIE CAM02 Colour Appearance Model

Directory of Open Access Journals (Sweden)

Dragoljub Novakovic

2010-06-01

Full Text Available Colour appearance models describe viewing conditions and enable simulating appearance of colours under different illuminants and illumination levels according to human perception. Since it is possible to predict how colour would look like when different illuminants are used, colour appearance models are incorporated in some monitor profiling software. Owing to these software, tone reproduction curve can be defined by taking into consideration viewing condition in which display is observed. In this work assessment of CIE CAM02 colour appearance model usage at calibrating LCD monitor for soft proof was tested in order to determine which tone reproduction curve enables better reproduction of colour. Luminance level was kept constant, whereas tone reproduction curves determined by gamma values and by parameters of CIE CAM02 model were varied. Testing was conducted in case where physical print reference is observed under illuminant which has colour temperature according to iso standard for soft-proofing (D50 and also for illuminants D65.  Based on the results of calibrations assessment, subjective and objective assessment of created profiles, as well as on the perceptual test carried out on human observers, differences in image display were defined and conclusions of the adequacy of CAM02 usage at monitor calibration for each of the viewing conditions reached.

Direct Imaging Discovery of a "Super-Jupiter" around the Late B-type Star κ And

NARCIS (Netherlands)

Carson, J.; et al., [Unknown; Thalmann, C.

2013-01-01

We present the direct imaging discovery of an extrasolar planet, or possible low-mass brown dwarf, at a projected separation of 55 ± 2 AU (1.''058 ± 0.''007) from the B9-type star κ And. The planet was detected with Subaru/HiCIAO during the SEEDS survey and confirmed as a bound companion via common

Understanding dental CAD/CAM for restorations--accuracy from a mechanical engineering viewpoint.

Science.gov (United States)

Tapie, Laurent; Lebon, Nicolas; Mawussi, Bernardin; Fron-Chabouis, Hélène; Duret, Francois; Attal, Jean-Pierre

2015-01-01

As is the case in the field of medicine, as well as in most areas of daily life, digital technology is increasingly being introduced into dental practice. Computer-aided design/ computer-aided manufacturing (CAD/CAM) solutions are available not only for chairside practice but also for creating inlays, crowns, fixed partial dentures (FPDs), implant abutments, and other dental prostheses. CAD/CAM dental practice can be considered as the handling of devices and software processing for the almost automatic design and creation of dental restorations. However, dentists who want to use dental CAD/CAM systems often do not have enough information to understand the variations offered by such technology practice. Knowledge of the random and systematic errors in accuracy with CAD/CAM systems can help to achieve successful restorations with this technology, and help with the purchasing of a CAD/CAM system that meets the clinical needs of restoration. This article provides a mechanical engineering viewpoint of the accuracy of CAD/ CAM systems, to help dentists understand the impact of this technology on restoration accuracy.

The use of CAM and conventional treatments among primary care consulters with chronic musculoskeletal pain.

Science.gov (United States)

Artus, Majid; Croft, Peter; Lewis, Martyn

2007-05-04

Chronic musculoskeletal pain is the single most cited reason for use of complementary and alternative medicine (CAM). Primary care is the most frequent conventional medical service used by patients with pain in the UK. We are unaware, however, of a direct evidence of the extent of CAM use by primary care patients, and how successful they perceive it to be. To determine CAM use among patients with chronic musculoskeletal pain who have consulted about their pain in primary care. Face-to-face interview-based survey. Three general practices in North Staffordshire. Respondents to a population pain survey who had reported having musculoskeletal pain in the survey and who had consulted about their pain in primary care in the previous 12 months as well as consenting to further research and agreeing to an interview. Information was gathered about their pain and the use of all treatments for pain, including CAM, in the previous year. 138 interviews were completed. 116 participants (84%) had used at least one CAM treatment for pain in the previous year. 65% were current users of CAM. The ratio of over-the-counter CAM use to care from a CAM provider was 3:2. 111 participants (80%) had used conventional treatment. 95 (69%) were using a combination of CAM and conventional treatment. Glucosamine and fish oil were the most commonly used CAM treatments (38%, 35% respectively). Most CAM treatments were scored on average as being helpful, and users indicated that they intended to use again 87% of the CAM treatments they had already used. We provide direct evidence that most primary care consulters with chronic musculoskeletal pain have used CAM in the previous year, usually in combination with conventional treatments. The high prevalence and wide range of users experiences of benefit and harm from CAM strengthen the argument for more research into this type of medicine to quantify benefit and assess safety. The observation that most users of conventional medicine also used CAM

Shared origins of a key enzyme during the evolution of C4 and CAM metabolism

Science.gov (United States)

Christin, Pascal-Antoine; Arakaki, Monica; Osborne, Colin P.; Bräutigam, Andrea; Sage, Rowan F.; Hibberd, Julian M.; Kelly, Steven; Covshoff, Sarah; Wong, Gane Ka-Shu; Hancock, Lillian; Edwards, Erika J.

2014-01-01

CAM and C4 photosynthesis are two key plant adaptations that have evolved independently multiple times, and are especially prevalent in particular groups of plants, including the Caryophyllales. We investigate the origin of photosynthetic PEPC, a key enzyme of both the CAM and C4 pathways. We combine phylogenetic analyses of genes encoding PEPC with analyses of RNA sequence data of Portulaca, the only plants known to perform both CAM and C4 photosynthesis. Three distinct gene lineages encoding PEPC exist in eudicots (namely ppc-1E1, ppc-1E2 and ppc-2), one of which (ppc-1E1) was recurrently recruited for use in both CAM and C4 photosynthesis within the Caryophyllales. This gene is present in multiple copies in the cacti and relatives, including Portulaca. The PEPC involved in the CAM and C4 cycles of Portulaca are encoded by closely related yet distinct genes. The CAM-specific gene is similar to genes from related CAM taxa, suggesting that CAM has evolved before C4 in these species. The similar origin of PEPC and other genes involved in the CAM and C4 cycles highlights the shared early steps of evolutionary trajectories towards CAM and C4, which probably diverged irreversibly only during the optimization of CAM and C4 phenotypes. PMID:24638902

LoCuSS: weak-lensing mass calibration of galaxy clusters

Science.gov (United States)

Okabe, Nobuhiro; Smith, Graham P.

2016-10-01

We present weak-lensing mass measurements of 50 X-ray luminous galaxy clusters at 0.15 ≤ z ≤ 0.3, based on uniform high-quality observations with Suprime-Cam mounted on the 8.2-m Subaru telescope. We pay close attention to possible systematic biases, aiming to control them at the ≲4 per cent level. The dominant source of systematic bias in weak-lensing measurements of the mass of individual galaxy clusters is contamination of background galaxy catalogues by faint cluster and foreground galaxies. We extend our conservative method for selecting background galaxies with (V - I') colours redder than the red sequence of cluster members to use a colour-cut that depends on cluster-centric radius. This allows us to define background galaxy samples that suffer ≤1 per cent contamination, and comprise 13 galaxies per square arcminute. Thanks to the purity of our background galaxy catalogue, the largest systematic that we identify in our analysis is a shape measurement bias of 3 per cent, that we measure using simulations that probe weak shears up to g = 0.3. Our individual cluster mass and concentration measurements are in excellent agreement with predictions of the mass-concentration relation. Equally, our stacked shear profile is in excellent agreement with the Navarro Frenk and White profile. Our new Local Cluster Substructure Survey mass measurements are consistent with the Canadian Cluster Cosmology Project and Cluster Lensing And Supernova Survey with Hubble surveys, and in tension with the Weighing the Giants at ˜1σ-2σ significance. Overall, the consensus at z ≤ 0.3 that is emerging from these complementary surveys represents important progress for cluster mass calibration, and augurs well for cluster cosmology.

Structure of the Milky Way stellar halo out to its outer boundary with blue horizontal-branch stars

Science.gov (United States)

Fukushima, Tetsuya; Chiba, Masashi; Homma, Daisuke; Okamoto, Sakurako; Komiyama, Yutaka; Tanaka, Masayuki; Tanaka, Mikito; Arimoto, Nobuo; Matsuno, Tadafumi

2018-06-01

We present the structure of the Milky Way stellar halo beyond Galactocentric distances of r = 50 kpc traced by blue horizontal-branch (BHB) stars, which are extracted from the survey data in the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP). We select BHB candidates based on (g, r, i, z) photometry, where the z-band is on the Paschen series and the colors that involve the z-band are sensitive to surface gravity. About 450 BHB candidates are identified between r = 50 kpc and 300 kpc, most of which are beyond the reach of previous large surveys, including the Sloan Digital Sky Survey. We find that the global structure of the stellar halo in this range has substructures, which are especially remarkable in the GAMA15H and XMM-LSS fields in the HSC-SSP. We find that the stellar halo can be fitted to a single power-law density profile with an index of α ≃ 3.3 (3.5) with (without) these fields and its global axial ratio is q ≃ 2.2 (1.3). Thus, the stellar halo may be significantly disturbed and be made in a prolate form by halo substructures, perhaps associated with the Sagittarius stream in its extension beyond r ˜ 100 kpc. For a broken power-law model allowing different power-law indices inside/outside a break radius, we obtain a steep power-law slope of α ≃ 5 outside a break radius of ˜100 kpc (200 kpc) for the case with (without) GAMA15H and XMM-LSS. This radius of 200 kpc might be as close as a halo boundary if there is any, although a larger BHB sample is required from further HSC-SSP surveys to increase its statistical significance.

GOLDRUSH. II. Clustering of galaxies at z ˜ 4-6 revealed with the half-million dropouts over the 100 deg2 area corresponding to 1 Gpc3

Science.gov (United States)

Harikane, Yuichi; Ouchi, Masami; Ono, Yoshiaki; Saito, Shun; Behroozi, Peter; More, Surhud; Shimasaku, Kazuhiro; Toshikawa, Jun; Lin, Yen-Ting; Akiyama, Masayuki; Coupon, Jean; Komiyama, Yutaka; Konno, Akira; Lin, Sheng-Chieh; Miyazaki, Satoshi; Nishizawa, Atsushi J.; Shibuya, Takatoshi; Silverman, John

2018-01-01

We present clustering properties from 579492 Lyman-break galaxies (LBGs) at z ˜ 4-6 over the 100 deg2 sky (corresponding to a 1.4 Gpc3 volume) identified in early data of the Hyper Suprime-Cam (HSC) Subaru Strategic Program survey. We derive angular correlation functions (ACFs) for the HSC LBGs with unprecedentedly high statistical accuracies at z ˜ 4-6, and compare them with the halo occupation distribution (HOD) models. We clearly identify significant ACF excesses in 10″ physical properties including the star formation rate (SFR), the stellar-to-halo mass ratio (SHMR), and the dark matter accretion rate (\\dot{M}_{ h}) over a wide mass range of Mh/M⊙ = 4 × 1010-4 × 1012. We find that the SHMR increases from z ˜ 4 to 7 by a factor of ˜4 at Mh ≃ 1 × 1011 M⊙ , while the SHMR shows no strong evolution in the similar redshift range at Mh ≃ 1 × 1012 M⊙ . Interestingly, we identify a tight relation of SFR/\\dot{M}_{ h}-Mh showing no significant evolution beyond 0.15 dex in this wide mass range over z ˜ 4-7. This weak evolution suggests that the SFR/\\dot{M}_{ h}-Mh relation is a fundamental relation in high-redshift galaxy formation whose star formation activities are regulated by the dark matter mass assembly. Assuming this fundamental relation, we calculate the cosmic star formation rate densities (SFRDs) over z = 0-10 (a.k.a. the Madau-Lilly plot). The cosmic SFRD evolution based on the fundamental relation agrees with the one obtained by observations, suggesting that the cosmic SFRD increase from z ˜ 10 to 4 - 2 (decrease from z ˜ 4-2 to 0) is mainly driven by the increase of the halo abundance (the decrease of the accretion rate).

Digital Dentistry — Digital Impression and CAD/CAM System Applications

Directory of Open Access Journals (Sweden)

Gabor Alin-Gabriel

2017-03-01

Full Text Available Digital imprint and computer-aided design/computer-aided manufacture (CAD/CAM systems offer several benefits compared to traditional techniques. The use of a CAD/CAM system to scan preparations and generate restorations in-office, removes a second appointment for the patient. The existence of precision benefits in using complete systems and chairside scanning systems, has been proven. CAD/CAM restorations have a good longevity and meet the accepted clinical parameters. New digital impression methods are presently accessible, and before long, the long-awaited goal of sparing patients of one the most unpleasant practices in clinical dentistry, acquiring dental impressions, will be exchanged by intraoral digital scanning. CAD/CAM systems existing nowadays, can feed data through accurate digital scans created from plaster models, straight to manufacturing systems that can shape ceramic or resin restorations with no requirement of a physical copy of the prepared, adjacent, and antagonist teeth.

Tracking vegetation phenology across diverse North American biomes using PhenoCam imagery: A new, publicly-available dataset

Science.gov (United States)

Richardson, A. D.

2015-12-01

Vegetation phenology controls the seasonality of many ecosystem processes, as well as numerous biosphere-atmosphere feedbacks. Phenology is highly sensitive to climate change and variability, and is thus a key aspect of global change ecology. The goal of the PhenoCam network is to serve as a long-term, continental-scale, phenological observatory. The network uses repeat digital photography—images captured using conventional, visible-wavelength, automated digital cameras—to characterize vegetation phenology in diverse ecosystems across North America and around the world. At present, imagery from over 200 research sites, spanning a wide range of ecoregions, climate zones, and plant functional types, is currently being archived and processed in near-real-time through the PhenoCam project web page (http://phenocam.sr.unh.edu/). Data derived from PhenoCam imagery have been previously used to evaluate satellite phenology products, to constrain and test new phenology models, to understand relationships between canopy phenology and ecosystem processes, and to study the seasonal changes in leaf-level physiology that are associated with changes in leaf color. I will describe a new, publicly-available phenological dataset, derived from over 600 site-years of PhenoCam imagery. For each archived image (ca. 5 million), we extracted RGB (red, green, blue) color channel information, with means and other statistics calculated across a region-of-interest (ROI) delineating a specific vegetation type. From the high-frequency (typically, 30 minute) imagery, we derived time series characterizing vegetation color, including "canopy greenness", processed to 1- and 3-day intervals. For ecosystems with a single annual cycle of vegetation activity, we derived estimates, with uncertainties, for the start, middle, and end of spring and autumn phenological transitions. Given the lack of multi-year, standardized, and geographically distributed phenological data for North America, we

Channeler Ant Model: 3 D segmentation of medical images through ant colonies

International Nuclear Information System (INIS)

Fiorina, E.; Valzano, S.; Arteche Diaz, R.; Bosco, P.; Gargano, G.; Megna, R.; Oppedisano, C.; Massafra, A.

2011-01-01

In this paper the Channeler Ant Model (CAM) and some results of its application to the analysis of medical images are described. The CAM is an algorithm able to segment 3 D structures with different shapes, intensity and background. It makes use of virtual and colonies and exploits their natural capabilities to modify the environment and communicate with each other by pheromone deposition. Its performance has been validated with the segmentation of 3 D artificial objects and it has been already used successfully in lung nodules detection on Computer Tomography images. This work tries to evaluate the CAM as a candidate to solve the quantitative segmentation problem in Magnetic Resonance brain images: to evaluate the percentage of white matter, gray matter and cerebrospinal fluid in each voxel.

Comparison of denture tooth movement between CAD-CAM and conventional fabrication techniques.

Science.gov (United States)

Goodacre, Brian J; Goodacre, Charles J; Baba, Nadim Z; Kattadiyil, Mathew T

2018-01-01

Data comparing the denture tooth movement of computer-aided design and computer-aided manufacturing (CAD-CAM) and conventional denture processing techniques are lacking. The purpose of this in vitro study was to compare the denture tooth movement of pack-and-press, fluid resin, injection, CAD-CAM-bonded, and CAD-CAM monolithic techniques for fabricating dentures to determine which process produces the most accurate and reproducible prosthesis. A total of 50 dentures were evaluated, 10 for each of the 5 groups. A master denture was fabricated and milled from prepolymerized poly(methyl methacrylate). For the conventional processing techniques (pack-and-press, fluid resin, and injection) a polyvinyl siloxane putty mold of the master denture was made in which denture teeth were placed and molten wax injected. The cameo surface of each wax-festooned denture was laser scanned, resulting in a standard tessellation language (STL) format file. The CAD-CAM dentures included 2 subgroups: CAD-CAM-bonded teeth in which the denture teeth were bonded into the milled denture base and CAD-CAM monolithic teeth in which the denture teeth were milled as part of the denture base. After all specimens had been fabricated, they were hydrated for 24 hours, and the cameo surface laser scanned. The preprocessing and postprocessing scan files of each denture were superimposed using surface-matching software. Measurements were made at 64 locations, allowing evaluation of denture tooth movement in a buccal, lingual, mesial-distal, and occlusal direction. The use of median and interquartile range values was used to assess accuracy and reproducibility. Levene and Kruskal-Wallis analyses of variance were used to evaluate differences between processing techniques (α=.05). The CAD-CAM monolithic technique was the most accurate, followed by fluid resin, CAD-CAM-bonded, pack-and-press, and injection. CAD-CAM monolithic technique was the most reproducible, followed by pack-and-press, CAD-CAM

The inducible CAM plants in putative lunar lander experiments

Science.gov (United States)

Burlak, Olexii; Zaetz, Iryna; Soldatkin, Olexii; Rogutskyy, Ivan; Danilchenko, Boris; Mikheev, Olexander; de Vera, Jean-Pierre; Vidmachenko, Anatolii; Foing, Bernard H.; Kozyrovska, Natalia

Precursory lunar lander experiments on growing plants in locker-based chambers will increase our understanding of effect of lunar conditions on plant physiology. The inducible CAM (Cras-sulacean Acid Metabolism)-plants are reasonable model for a study of relationships between environmental challenges and changes in plant/bacteria gene expression. In inducible CAM-plants the enzymatic machinery for the environmentally activated CAM switches on from a C3-to a full-CAM mode of photosynthesis in response to any stresses (Winter et al., 2008). In our study, Kalanchoe spp. are shown to be promising candidates for putative lunar experiments as resistant to irradiation and desiccation, especially after inoculation with a bacterial consortium (Boorlak et al., 2010). Within frames of the experiment we expect to get information about the functional activity of CAM-plants, in particular, its organogenesis, photosystem, the circadian regulation of plant metabolism on the base of data gaining with instrumental indications from expression of the reporter genes fused to any genes involved in vital functions of the plant (Kozyrovska et al., 2009). References 1. Winter K., Garcia M., Holtum J. (2008) J. Exp. Bot. 59(7):1829-1840 2. Bourlak O., Lar O., Rogutskyy I., Mikheev A., Zaets I., Chervatyuk N., de Vera J.-P., Danilchenko A.B. Foing B.H., zyrovska N. (2010) Space Sci. Technol. 3. Kozyrovska N.O., Vidmachenko A.P., Foing B.H. et al. Exploration/call/estec/ESA. 2009.

Travel and exile. From Ovidio to Camões: Filinto, Garrett and Herculano

Directory of Open Access Journals (Sweden)

Maria Fernanda de Abreu

2016-07-01

Full Text Available Travel, in exile forced situation, provides images of identity, personal and collective representations, that literature has transmitted throughout its history. In this essay, we refer to models that in the so-called “Western Lit­erature” comes from Homer and Ovid, and that in the Portuguese one are updated by, among others, Luís de Camões, Filinto Elíseo e Almeida Gar­rett; a case study shows us the use of the topic of storm in exile writing, in the romantic Alexandre Herculano work.

Marginal adaptation and CAD-CAM technology: A systematic review of restorative material and fabrication techniques.

Science.gov (United States)

Papadiochou, Sofia; Pissiotis, Argirios L

2018-04-01

The comparative assessment of computer-aided design and computer-aided manufacturing (CAD-CAM) technology and other fabrication techniques pertaining to marginal adaptation should be documented. Limited evidence exists on the effect of restorative material on the performance of a CAD-CAM system relative to marginal adaptation. The purpose of this systematic review was to investigate whether the marginal adaptation of CAD-CAM single crowns, fixed dental prostheses, and implant-retained fixed dental prostheses or their infrastructures differs from that obtained by other fabrication techniques using a similar restorative material and whether it depends on the type of restorative material. An electronic search of English-language literature published between January 1, 2000, and June 30, 2016, was conducted of the Medline/PubMed database. Of the 55 included comparative studies, 28 compared CAD-CAM technology with conventional fabrication techniques, 12 contrasted CAD-CAM technology and copy milling, 4 compared CAD-CAM milling with direct metal laser sintering (DMLS), and 22 investigated the performance of a CAD-CAM system regarding marginal adaptation in restorations/infrastructures produced with different restorative materials. Most of the CAD-CAM restorations/infrastructures were within the clinically acceptable marginal discrepancy (MD) range. The performance of a CAD-CAM system relative to marginal adaptation is influenced by the restorative material. Compared with CAD-CAM, most of the heat-pressed lithium disilicate crowns displayed equal or smaller MD values. Slip-casting crowns exhibited similar or better marginal accuracy than those fabricated with CAD-CAM. Cobalt-chromium and titanium implant infrastructures produced using a CAD-CAM system elicited smaller MD values than zirconia. The majority of cobalt-chromium restorations/infrastructures produced by DMLS displayed better marginal accuracy than those fabricated with the casting technique. Compared with copy

Gas exchange and leaf anatomy of a C3-CAM hybrid, Yucca gloriosa (Asparagaceae).

Science.gov (United States)

Heyduk, Karolina; Burrell, Nia; Lalani, Falak; Leebens-Mack, Jim

2016-03-01

While the majority of plants use the typical C3 carbon metabolic pathway, ~6% of angiosperms have adapted to carbon limitation as a result of water stress by employing a modified form of photosynthesis known as Crassulacean acid metabolism (CAM). CAM plants concentrate carbon in the cells by temporally separating atmospheric carbon acquisition from fixation into carbohydrates. CAM has been studied for decades, but the evolutionary progression from C3 to CAM remains obscure. In order to better understand the morphological and physiological characteristics associated with CAM photosynthesis, phenotypic variation was assessed in Yucca aloifolia, a CAM species, Yucca filamentosa, a C3 species, and Yucca gloriosa, a hybrid species derived from these two yuccas exhibiting intermediate C3-CAM characteristics. Gas exchange, titratable leaf acidity, and leaf anatomical traits of all three species were assayed in a common garden under well-watered and drought-stressed conditions. Yucca gloriosa showed intermediate phenotypes for nearly all traits measured, including the ability to acquire carbon at night. Using the variation found among individuals of all three species, correlations between traits were assessed to better understand how leaf anatomy and CAM physiology are related. Yucca gloriosa may be constrained by a number of traits which prevent it from using CAM to as high a degree as Y. aloifolia. The intermediate nature of Y. gloriosa makes it a promising system in which to study the evolution of CAM. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

Perspectives of complementary and alternative medicine (CAM) practitioners in the support and treatment of infertility.

Science.gov (United States)

O'Reilly, Erin; Sevigny, Marika; Sabarre, Kelley-Anne; Phillips, Karen P

2014-10-14

Infertility patients are increasingly using complementary and alternative medicine (CAM) to supplement or replace conventional fertility treatments. The objective of this study was to determine the roles of CAM practitioners in the support and treatment of infertility. Ten semi-structured interviews were conducted in Ottawa, Canada in 2011 with CAM practitioners who specialized in naturopathy, acupuncture, traditional Chinese medicine, hypnotherapy and integrated medicine. CAM practitioners played an active role in both treatment and support of infertility, using a holistic, interdisciplinary and individualized approach. CAM practitioners recognized biological but also environmental and psychosomatic determinants of infertility. Participants were receptive to working with physicians, however little collaboration was described. Integrated infertility patient care through both collaboration with CAM practitioners and incorporation of CAM's holistic, individualized and interdisciplinary approaches would greatly benefit infertility patients.

The use of CAM and conventional treatments among primary care consulters with chronic musculoskeletal pain

Directory of Open Access Journals (Sweden)

Lewis Martyn

2007-05-01

Full Text Available Abstract Background Chronic musculoskeletal pain is the single most cited reason for use of complementary and alternative medicine (CAM. Primary care is the most frequent conventional medical service used by patients with pain in the UK. We are unaware, however, of a direct evidence of the extent of CAM use by primary care patients, and how successful they perceive it to be. Methods Aims and objectives To determine CAM use among patients with chronic musculoskeletal pain who have consulted about their pain in primary care. Study design Face-to-face interview-based survey. Setting Three general practices in North Staffordshire. Participants Respondents to a population pain survey who had reported having musculoskeletal pain in the survey and who had consulted about their pain in primary care in the previous 12 months as well as consenting to further research and agreeing to an interview. Information was gathered about their pain and the use of all treatments for pain, including CAM, in the previous year. Results 138 interviews were completed. 116 participants (84% had used at least one CAM treatment for pain in the previous year. 65% were current users of CAM. The ratio of over-the-counter CAM use to care from a CAM provider was 3:2. 111 participants (80% had used conventional treatment. 95 (69% were using a combination of CAM and conventional treatment. Glucosamine and fish oil were the most commonly used CAM treatments (38%, 35% respectively. Most CAM treatments were scored on average as being helpful, and users indicated that they intended to use again 87% of the CAM treatments they had already used. Conclusion We provide direct evidence that most primary care consulters with chronic musculoskeletal pain have used CAM in the previous year, usually in combination with conventional treatments. The high prevalence and wide range of users experiences of benefit and harm from CAM strengthen the argument for more research into this type of medicine

THE MULTIWAVELENGTH SURVEY BY YALE-CHILE (MUSYC): DEEP MEDIUM-BAND OPTICAL IMAGING AND HIGH-QUALITY 32-BAND PHOTOMETRIC REDSHIFTS IN THE ECDF-S

International Nuclear Information System (INIS)

Cardamone, Carolin N.; Van Dokkum, Pieter G.; Urry, C. Megan; Brammer, Gabriel; Taniguchi, Yoshi; Gawiser, Eric; Bond, Nicholas; Taylor, Edward; Damen, Maaike; Treister, Ezequiel; Cobb, Bethany E.; Schawinski, Kevin; Lira, Paulina; Murayama, Takashi; Saito, Tomoki; Sumikawa, Kentaro

2010-01-01

We present deep optical 18-medium-band photometry from the Subaru telescope over the ∼30' x 30' Extended Chandra Deep Field-South, as part of the Multiwavelength Survey by Yale-Chile (MUSYC). This field has a wealth of ground- and space-based ancillary data, and contains the GOODS-South field and the Hubble Ultra Deep Field. We combine the Subaru imaging with existing UBVRIzJHK and Spitzer IRAC images to create a uniform catalog. Detecting sources in the MUSYC 'BVR' image we find ∼40,000 galaxies with R AB 3.5. For 0.1 < z < 1.2, we find a 1σ scatter in Δz/(1 + z) of 0.007, similar to results obtained with a similar filter set in the COSMOS field. As a demonstration of the data quality, we show that the red sequence and blue cloud can be cleanly identified in rest-frame color-magnitude diagrams at 0.1 < z < 1.2. We find that ∼20% of the red sequence galaxies show evidence of dust emission at longer rest-frame wavelengths. The reduced images, photometric catalog, and photometric redshifts are provided through the public MUSYC Web site.

A mobile app for securely capturing and transferring clinical images to the electronic health record: description and preliminary usability study.

Science.gov (United States)

Landman, Adam; Emani, Srinivas; Carlile, Narath; Rosenthal, David I; Semakov, Simon; Pallin, Daniel J; Poon, Eric G

2015-01-02

Photographs are important tools to record, track, and communicate clinical findings. Mobile devices with high-resolution cameras are now ubiquitous, giving clinicians the opportunity to capture and share images from the bedside. However, secure and efficient ways to manage and share digital images are lacking. The aim of this study is to describe the implementation of a secure application for capturing and storing clinical images in the electronic health record (EHR), and to describe initial user experiences. We developed CliniCam, a secure Apple iOS (iPhone, iPad) application that allows for user authentication, patient selection, image capture, image annotation, and storage of images as a Portable Document Format (PDF) file in the EHR. We leveraged our organization's enterprise service-oriented architecture to transmit the image file from CliniCam to our enterprise clinical data repository. There is no permanent storage of protected health information on the mobile device. CliniCam also required connection to our organization's secure WiFi network. Resident physicians from emergency medicine, internal medicine, and dermatology used CliniCam in clinical practice for one month. They were then asked to complete a survey on their experience. We analyzed the survey results using descriptive statistics. Twenty-eight physicians participated and 19/28 (68%) completed the survey. Of the respondents who used CliniCam, 89% found it useful or very useful for clinical practice and easy to use, and wanted to continue using the app. Respondents provided constructive feedback on location of the photos in the EHR, preferring to have photos embedded in (or linked to) clinical notes instead of storing them as separate PDFs within the EHR. Some users experienced difficulty with WiFi connectivity which was addressed by enhancing CliniCam to check for connectivity on launch. CliniCam was implemented successfully and found to be easy to use and useful for clinical practice. CliniCam is

Evaluating EUV mask pattern imaging with two EUV microscopes

International Nuclear Information System (INIS)

Goldberg, Kenneth A.; Takase, Kei; Naulleau, Patrick P.; Han, Hakseung; Barty, Anton; Kinoshita, Hiroo; Hamamoto, Kazuhiro

2008-01-01

Aerial image measurement plays a key role in the development of patterned reticles for each generation of lithography. Studying the field transmitted (reflected) from EUV masks provides detailed information about potential disruptions caused by mask defects, and the performance of defect repair strategies, without the complications of photoresist imaging. Furthermore, by measuring the continuously varying intensity distribution instead of a thresholded, binary resist image, aerial image measurement can be used as feedback to improve mask and lithography system modeling methods. Interest in EUV, at-wavelength, aerial image measurement lead to the creation of several research tools worldwide. These tools are used in advanced mask development work, and in the evaluation of the need for commercial at-wavelength inspection tools. They describe performance measurements of two such tools, inspecting the same EUV mask in a series of benchmarking tests that includes brightfield and darkfield patterns. One tool is the SEMATECH Berkeley Actinic Inspection Tool (AIT) operating on a bending magnet beamline at Lawrence Berkeley National Laboratory's Advanced Light Source. The AIT features an EUV Fresnel zoneplate microscope that emulates the numerical aperture of a 0.25-NA stepper, and projects the aerial image directly onto a CCD camera, with 700x magnification. The second tool is an EUV microscope (EUVM) operating at the NewSUBARU synchrotron in Hyogo, Japan. The NewSUBARU tool projects the aerial image using a reflective, 30x Schwarzschild objective lens, followed by a 10-200x x-ray zooming tube. The illumination conditions and the imaging etendue are different for the two tools. The benchmarking measurements were used to determine many imaging and performance properties of the tools, including resolution, modulation transfer function (MTF), aberration magnitude, aberration field-dependence (including focal-plane tilt), illumination uniformity, line-edge roughness, and flare

The CUPCIG (CAM-Use in Primary Care in Germany) Study:Part I-Pain. Study Protocol of a Pilot-trial to Assess Feasibility, Acceptability and Perceived Effectiveness of CAM in Pain Disorders in Primary Care.

Science.gov (United States)

Schencking, Martin; Sönnichsen, Andreas; Bassüner, Susanne; Redaelli, Marcus

2015-01-01

There is limited valid data available on CAM procedures for chronic joint and neuropathic pain in primary care in Germany. Indiviual CAM qualifications of the general practitioners (GPs) and the potential of cost reduction through CAM treatment are almost unknown. The aim of this pilot trial preceding the main study is to examine the survey mode, to estimate the response rate by GPs with or without an additional qualification for CAM, and to identify the status quo in therapeutic approaches for chronic pain disorders in primary care. This is a cross-sectional study with an ex post facto design among German GPs consisting of 2 parts: In a first step, a pilot trial precedes the main study targeting 200 GPs with and 200 GPs without additional qualification in CAM in a selected region. The results of the CUPCIG study comprise the distribution of pain types treated in primary care practices, the GPs' attitude toward complementary pain therapy, pharmacological or CAM treatment, the estimate of cost reduction through CAM treatment of pain, the application of diverse CAM procedures, and biographical data. The CUPCIG study serves to compile pain therapy approaches in primary care in Germany with respect to the individual CAM expertise of the GPs. © 2015 S. Karger GmbH, Freiburg.

Introduction of effect and consideration of the introduction of CAD/CAM system

International Nuclear Information System (INIS)

Kang, Man Ok

1984-12-01

This reports introduction of effect and consideration of the introduction of computer-aided design and computer aided manufacturing system. It includes outline of CAD/CAM system like definition, classification, system kinds, and development process of CAD/CAM system, technology, market trend development prospect, and value on introduction of this system, and current application of CAD/CAM system in major application area, development countries and Korea.

S-Cam 3: Optical astronomy with a STJ-based imaging spectrophotometer

International Nuclear Information System (INIS)

Verhoeve, P.; Martin, D.D.E.; Hijmering, R.A.; Verveer, J.; Dordrecht, A. van; Sirbi, G.; Oosterbroek, T.; Peacock, A.

2006-01-01

S-Cam 3 is the third generation of a cryogenic camera, based on superconducting tunnel junctions (STJs), for ground-based optical astronomy, deployed at the 4.2 m William Herschel Telescope (WHT) at La Palma (Spain). It exploits a 10x12 pixel array of Ta/Al STJs, covering a field of view of ∼9''x11'' on the sky. The wavelength band extends from 330-750 nm, with a wavelength resolving power of ∼10 at 500 nm. The detectors are operated at ∼285 mK, achieved with a double stage 4 He- 3 He sorption cooler. Each pixel has its own electronic readout chain at room temperature, with a JFET-based charge sensitive preamplifier. The instrument has undergone extensive testing and calibration, followed by the first observation campaign at La Palma in July 2004. This campaign has focused on point sources with time variability, exploiting the instrument's unique combination of spectrophotometry with high time resolution

Child/Adolescent Anxiety Multimodal Study (CAMS: rationale, design, and methods

Directory of Open Access Journals (Sweden)

Waslick Bruce D

2010-01-01

Full Text Available Abstract Objective To present the design, methods, and rationale of the Child/Adolescent Anxiety Multimodal Study (CAMS, a recently completed federally-funded, multi-site, randomized placebo-controlled trial that examined the relative efficacy of cognitive-behavior therapy (CBT, sertraline (SRT, and their combination (COMB against pill placebo (PBO for the treatment of separation anxiety disorder (SAD, generalized anxiety disorder (GAD and social phobia (SoP in children and adolescents. Methods Following a brief review of the acute outcomes of the CAMS trial, as well as the psychosocial and pharmacologic treatment literature for pediatric anxiety disorders, the design and methods of the CAMS trial are described. Results CAMS was a six-year, six-site, randomized controlled trial. Four hundred eighty-eight (N = 488 children and adolescents (ages 7-17 years with DSM-IV-TR diagnoses of SAD, GAD, or SoP were randomly assigned to one of four treatment conditions: CBT, SRT, COMB, or PBO. Assessments of anxiety symptoms, safety, and functional outcomes, as well as putative mediators and moderators of treatment response were completed in a multi-measure, multi-informant fashion. Manual-based therapies, trained clinicians and independent evaluators were used to ensure treatment and assessment fidelity. A multi-layered administrative structure with representation from all sites facilitated cross-site coordination of the entire trial, study protocols and quality assurance. Conclusions CAMS offers a model for clinical trials methods applicable to psychosocial and psychopharmacological comparative treatment trials by using state-of-the-art methods and rigorous cross-site quality controls. CAMS also provided a large-scale examination of the relative and combined efficacy and safety of the best evidenced-based psychosocial (CBT and pharmacologic (SSRI treatments to date for the most commonly occurring pediatric anxiety disorders. Primary and secondary results

PhenoCam Dataset v1.0: Digital Camera Imagery from the PhenoCam Network, 2000-2015

Data.gov (United States)

National Aeronautics and Space Administration — This dataset provides a time series of visible-wavelength digital camera imagery collected through the PhenoCam Network at each of 133 sites in North America and...

Day/night regulation of aquaporins during the CAM cycle in Mesembryanthemum crystallinum.

Science.gov (United States)

Vera-Estrella, Rosario; Barkla, Bronwyn J; Amezcua-Romero, Julio C; Pantoja, Omar

2012-03-01

Mesembryanthemum crystallinum exhibits induction of Crassulacean acid metabolism (CAM) after a threshold stage of development, by exposure to long days with high light intensities or by water and salt stress. During the CAM cycle, fluctuations in carbon partitioning within the cell lead to transient drops in osmotic potential, which are likely stabilized/balanced by passive movement of water via aquaporins (AQPs). Protoplast swelling assays were used to detect changes in water permeability during the day/night cycle of CAM. To assess the role of AQPs during the same period, we followed transcript accumulation and protein abundance of four plasma membrane intrinsic proteins (PIPs) and one tonoplast intrinsic protein (TIP). CAM plants showed a persistent rhythm of specific AQP protein abundance changes throughout the day/night cycle, including changes in amount of McPIP2;1, McTIP1;2, McPIP1;4 and McPIP1;5, while the abundance of McPIP1;2 was unchanged. These protein changes did not appear to be coordinated with transcript levels for any of the AQPs analysed; however, they did occur in parrallel to alterations in water permeability, as well as variations in cell osmolarity, pinitol, glucose, fructose and phosphoenolpyruvate carboxylase (PEPc) levels measured throughout the day/night CAM cycle. Results suggest a role for AQPs in maintaining water balance during CAM and highlight the complexity of protein expression during the CAM cycle. © 2011 Blackwell Publishing Ltd.

A methodological framework for evaluating the evidence for Complementary and Alternative Medicine (CAM) for cancer

DEFF Research Database (Denmark)

Zachariae, Robert; Johannesen, Helle

2011-01-01

In spite of lacking evidence for effects on cancer progression itself, an increasing number of cancer patients use various types of complementary and alternative medicine (CAM). There is disagreement between CAM practitioners, researchers and clinical oncologists, as to how evidence concerning...... effects of CAM can and should be produced, and how the existing evidence should be interpreted. This represents a considerable challenge for oncologists; both in terms of patient needs for an informed dialogue regarding CAM, and because some types of CAM may interact with standard treatments....... There is a need for insight into which kinds of CAM may work, for whom they work, what the possible effects and side-effects are, and in what ways such effects may come about. The present article presents a framework for evaluating effects of CAM by suggesting a taxonomy of different levels of evidence related...

Phenotype-dependent effects of EpCAM expression on growth and invasion of human breast cancer cell lines

International Nuclear Information System (INIS)

Martowicz, Agnieszka; Spizzo, Gilbert; Gastl, Guenther; Untergasser, Gerold

2012-01-01

The epithelial cell adhesion molecule (EpCAM) has been shown to be overexpressed in breast cancer and stem cells and has emerged as an attractive target for immunotherapy of breast cancer patients. This study analyzes the effects of EpCAM on breast cancer cell lines with epithelial or mesenchymal phenotype. For this purpose, shRNA-mediated knockdown of EpCAM gene expression was performed in EpCAM high breast cancer cell lines with epithelial phenotype (MCF-7, T47D and SkBR3). Moreover, EpCAM low breast carcinoma cell lines with mesenchymal phenotype (MDA-MB-231, Hs578t) and inducible overexpression of EpCAM were used to study effects on proliferation, migration and in vivo growth. In comparison to non-specific silencing controls (n/s-crtl) knockdown of EpCAM (E#2) in EpCAM high cell lines resulted in reduced cell proliferation under serum-reduced culture conditions. Moreover, DNA synthesis under 3D culture conditions in collagen was significantly reduced. Xenografts of MCF-7 and T47D cells with knockdown of EpCAM formed smaller tumors that were less invasive. EpCAM low cell lines with tetracycline-inducible overexpression of EpCAM showed no increased cell proliferation or migration under serum-reduced growth conditions. MDA-MB-231 xenografts with EpCAM overexpression showed reduced invasion into host tissue and more infiltrates of chicken granulocytes. The role of EpCAM in breast cancer strongly depends on the epithelial or mesenchymal phenotype of tumor cells. Cancer cells with epithelial phenotype need EpCAM as a growth- and invasion-promoting factor, whereas tumor cells with a mesenchymal phenotype are independent of EpCAM in invasion processes and tumor progression. These findings might have clinical implications for EpCAM-based targeting strategies in patients with invasive breast cancer

Longevity of Single-Tooth All-Ceramic CAD/CAM Restorations: A Meta-Analysis

Science.gov (United States)

2013-07-01

to the application of CAD/CAM technology in dentistry . The initial monetary investment for the equipment is significant. Systems currently on the...CURRENT DENTAL CAD/CAM SYSTEMS Current CAD/CAM systems in dentistry include: CEREC (CEramic REConstruction) and CEREC Acquisition Center (AC) with...of Adhesive Dentistry , 1 (3), 255- 265. 42     Bindl A, & Mörmann W. (2002). An up to 5-year clinical evaluation of posterior In- Ceram CAD

Evaluation of the Usefulness of Virtual Chromoendoscopy with Different Color Modes in the MiroCam® System for Characterization of Small Bowel Lesions

Directory of Open Access Journals (Sweden)

Joana Ribeiro da Silva

2018-01-01

Full Text Available Background: Virtual chromoendoscopy (VC in small bowel capsule endoscopy can improve the visualization and characterization of different small bowel lesions (SBLs. There are few studies of its usefulness in the Given® system, and there is no evidence yet of its utility in the MiroCam® system. Aim: The aim of this study was to evaluate whether VC can improve the characterization of SBLs with the MiroCam® system. Methods: Twenty-two patients were selected, in which 100 elementary lesions were identified, including erosions (n = 45, ulcers (n = 17, and angioectasias (n = 38. For each lesion identified, images were captured without chromoendoscopy (normal image [NI] and with chromoendoscopy modes 1 (color mode [CM] 1, 2 (CM2, and 3 (CM3. A score from 1 to 4 was assigned to each image, in which a better evaluation of the characteristics and limits of the lesion was classified in ascending order, where 1 is the worst and 4 the best evaluation. The scores of the various modes were compared with Kendall's tau-c coefficient. Results: The average scores attributed to the photographs in NI, CM1, CM2, and CM3 were 3.83, 2.89, 1.85, and 1.43, respectively (tau-c = -0.75, p p p p Conclusions: VC using the CMs available in the MiroCam® system has not proven useful for a better assessment of any of the SBLs.

Availability Analysis of the Ventilation Stack CAM Interlock System

CERN Document Server

Young, J

2000-01-01

Ventilation Stack Continuous Air Monitor (CAM) Interlock System failure modes, failure frequencies, and system availability have been evaluated for the RPP. The evaluation concludes that CAM availability is as high as assumed in the safety analysis and that the current routine system surveillance is adequate to maintain this availability credited in the safety analysis, nor is such an arrangement predicted to significantly improve system availability.

DIRECT IMAGING CONFIRMATION AND CHARACTERIZATION OF A DUST-ENSHROUDED CANDIDATE EXOPLANET ORBITING FOMALHAUT

Energy Technology Data Exchange (ETDEWEB)

Currie, Thayne [Department of Astronomy and Astrophysics, University of Toronto, Toronto, ON (Canada); Debes, John [Space Telescope Science Institute, Baltimore, MD (United States); Rodigas, Timothy J. [Steward Observatory, University of Arizona, Tucson, AZ (United States); Burrows, Adam [Department of Astrophysical Sciences, Princeton University, Princeton, NJ (United States); Itoh, Yoichi [Nishi-Harima Observatory, University of Hyogo, Kobe (Japan); Fukagawa, Misato [Department of Earth and Space Sciences, Osaka University, Osaka (Japan); Kenyon, Scott J. [Smithsonian Astrophysical Observatory, Cambridge, MA (United States); Kuchner, Marc [Stellar and Exoplanets Laboratory, NASA-Goddard Space Flight Center, Greenbelt, MD (United States); Matsumura, Soko, E-mail: currie@astro.utoronto.ca [Department of Astronomy, University of Maryland-College Park, College Park, MD (United States)

2012-12-01

We present Subaru/IRCS J-band data for Fomalhaut and a (re)reduction of archival 2004-2006 HST/ACS data first presented by Kalas et al. We confirm the existence of a candidate exoplanet, Fomalhaut b, in both the 2004 and 2006 F606W data sets at a high signal-to-noise ratio. Additionally, we confirm the detection at F814W and present a new detection in F435W. Fomalhaut b's space motion may be consistent with it being in an apsidally aligned, non-debris ring-crossing orbit, although new astrometry is required for firmer conclusions. We cannot confirm that Fomalhaut b exhibits 0.7-0.8 mag variability cited as evidence for planet accretion or a semi-transient dust cloud. The new, combined optical spectral energy distribution and IR upper limits confirm that emission identifying Fomalhaut b originates from starlight scattered by small dust, but this dust is most likely associated with a massive body. The Subaru and IRAC/4.5 {mu}m upper limits imply M < 2 M{sub J} , still consistent with the range of Fomalhaut b masses needed to sculpt the disk. Fomalhaut b is very plausibly 'a planet identified from direct imaging' even if current images of it do not, strictly speaking, show thermal emission from a directly imaged planet.

Comparison of Flexural Strength of Different CAD/CAM PMMA-Based Polymers.

Science.gov (United States)

Alp, Gülce; Murat, Sema; Yilmaz, Burak

2018-01-28

To compare the flexural strength of different computer-aided design/computer-aided manufacturing (CAD/CAM) poly(methyl methacrylate)-based (PMMA) polymers and conventional interim resin materials after thermocycling. Rectangular-shaped specimens (n = 15, for each material) (25 × 2 × 2 mm 3 ) were fabricated from 3 CAD/CAM PMMA-based polymers (Telio CAD [T]; M-PM-Disc [M]; Polident-PMMA [P]), 1 bis-acrylate composite resin (Protemp 4 [PT]), and 1 conventional PMMA (ArtConcept Artegral Dentine [C]) according to ISO 10477:2004 Standards (Dentistry-Polymer-Based Crown and Bridge Materials). The specimens were subjected to 10,000 thermocycles (5 to 55°C). Three-point flexural strength of the specimens was tested in a universal testing machine at a 1.0 mm/min crosshead speed, and the flexural strength data (σ) were calculated (MPa). The flexural strength values were statistically analyzed using 1-way ANOVA, and Tukey HSD post-hoc test for multiple comparisons (α = 0.05). Flexural strength values ranged between 66.1 ± 13.1 and 131.9 ± 19.8 MPa. There were significant differences among the flexural strengths of tested materials, except for between T and P CAD/CAM PMMA-based polymers (p > 0.05). CAD/CAM PMMA-based polymer M had the highest flexural strength and conventional PMMA had the lowest (p CAD/CAM PMMA-based T and P polymers had significantly higher flexural strength than the bis-acrylate composite resin (p CAD/CAM PMMA-based M (p CAD/CAM PMMA-based polymers was greater than the flexural strength of bis-acrylate composite resin, which had a greater flexural strength compared to conventional PMMA resin. © 2018 by the American College of Prosthodontists.

Do CAD/CAM dentures really release less monomer than conventional dentures?

Science.gov (United States)

Steinmassl, Patricia-Anca; Wiedemair, Verena; Huck, Christian; Klaunzer, Florian; Steinmassl, Otto; Grunert, Ingrid; Dumfahrt, Herbert

2017-06-01

Computer-aided design (CAD)/computer-aided manufacturing (CAM) dentures are assumed to have more favourable material properties than conventionally fabricated dentures, among them a lower methacrylate monomer release. The aim of this study was to test this hypothesis. CAD/CAM dentures were generated from ten different master casts by using four different CAD/CAM systems. Conventional, heat-polymerised dentures served as control group. Denture weight and volume were measured; the density was calculated, and the denture surface area was assessed digitally. The monomer release after 7 days of water storage was measured by high-performance liquid chromatography. Whole You Nexteeth and Wieland Digital Dentures had significantly lower mean volume and weight than conventional dentures. Baltic Denture System and Whole You Nexteeth had a significantly increased density. Baltic Denture System had a significantly smaller surface area. None of the CAD/CAM dentures released significantly less monomer than the control group. All tested dentures released very low amounts of methacrylate monomer, but not significantly less than conventional dentures. A statistically significant difference might nevertheless exist in comparison to other, less recommendable denture base materials, such as the frequently used autopolymerising resins. CAD/CAM denture fabrication has numerous advantages. It enables the fabrication of dentures with lower resin volume and lower denture weight. Both could increase the patient comfort. Dentures with higher density might exhibit more favourable mechanical properties. The hypothesis that CAD/CAM dentures release less monomer than conventional dentures could, however, not be verified.

Sobre figuras de oposição em dois sonetos de Camões

OpenAIRE

Marnoto, Rita

2012-01-01

(2012). Sobre figuras de oposição em dois sonetos de Camões. In Rita Marnoto (Coord.), Comentário a Camões. Vol. 1. Sonetos (147-204). Lisboa: CIEC, Cotovia. ISBN 978 972 795 330 1 figuras de oposição, visão histórica e seu uso em dois sonetos de Camões

Cam-Follower Mechanism Design for Narrow Loom Beat Up Motion ...

African Journals Online (AJOL)

The topology of the kinematics is developed by using the graph theory method of kinematic synthesis. The forces required to drive the plate-cam and follower system were modeled and the components such as the plate-cam, camshaft, the follower and the drive mechanism were synthesized for smooth operation of the ...

Understanding dental CAD/CAM for restorations--the digital workflow from a mechanical engineering viewpoint.

Science.gov (United States)

Tapie, L; Lebon, N; Mawussi, B; Fron Chabouis, H; Duret, F; Attal, J-P

2015-01-01

As digital technology infiltrates every area of daily life, including the field of medicine, so it is increasingly being introduced into dental practice. Apart from chairside practice, computer-aided design/computer-aided manufacturing (CAD/CAM) solutions are available for creating inlays, crowns, fixed partial dentures (FPDs), implant abutments, and other dental prostheses. CAD/CAM dental solutions can be considered a chain of digital devices and software for the almost automatic design and creation of dental restorations. However, dentists who want to use the technology often do not have the time or knowledge to understand it. A basic knowledge of the CAD/CAM digital workflow for dental restorations can help dentists to grasp the technology and purchase a CAM/CAM system that meets the needs of their office. This article provides a computer-science and mechanical-engineering approach to the CAD/CAM digital workflow to help dentists understand the technology.

CAM therapies among primary care patients using opioid therapy for chronic pain

OpenAIRE

Fleming, Sara; Rabago, David P; Mundt, Marlon P; Fleming, Michael F

2007-01-01

Abstract Background Complementary and alternative medicine (CAM) is an increasingly common therapy used to treat chronic pain syndromes. However; there is limited information on the utilization and efficacy of CAM therapy in primary care patients receiving long-term opioid therapy. Method A survey of CAM therapy was conducted with a systematic sample of 908 primary care patients receiving opioids as a primary treatment method for chronic pain. Subjects completed a questionnaire designed to as...

Accuracy Assessment of Immediate and Delayed Implant Placements Using CAD/CAM Surgical Guides.

Science.gov (United States)

Alzoubi, Fawaz; Massoomi, Nima; Nattestad, Anders

2016-10-01

The aim of this study is to assess the accuracy of immediately placed implants using Anatomage Invivo5 computer-assisted design/computer-assisted manufacturing (CAD/CAM) surgical guides and compare the accuracy to delayed implant placement protocol. Patients who had implants placed using Anatomage Invivo5 CAD/CAM surgical guides during the period of 2012-2015 were evaluated retrospectively. Patients who received immediate implant placements and/or delayed implant placements replacing 1-2 teeth were included in this study. Pre- and postsurgical images were superimposed to evaluate deviations at the crest, apex, and angle. A total of 40 implants placed in 29 patients were included in this study. The overall mean deviations measured at the crest, apex, and angle were 0.86 mm, 1.25 mm, and 3.79°, respectively. The means for the immediate group deviations were: crest = 0.85 mm, apex = 1.10, and angle = 3.49°. The means for the delayed group deviations were: crest = 0.88 mm, apex = 1.59, and angle = 4.29°. No statistically significant difference was found at the crest and angle; however, there was a statistically significant difference between the immediate and delayed group at the apex, with the immediate group presenting more accurate placements at the apical point than the delayed group. CAD/CAM surgical guides can be reliable tools to accurately place implants immediately and/or in a delayed fashion. No statistically significant differences were found between the delayed and the immediate group at the crest and angle, however apical position was more accurate in the immediate group.

Treatment expectations for CAM interventions in pediatric chronic pain patients and their parents.

Science.gov (United States)

Tsao, Jennie C I; Meldrum, Marcia; Bursch, Brenda; Jacob, Margaret C; Kim, Su C; Zeltzer, Lonnie K

2005-12-01

Patient expectations regarding complementary and alternative medicine (CAM) interventions have important implications for treatment adherence, attrition and clinical outcome. Little is known, however, about parent and child treatment expectations regarding CAM approaches for pediatric chronic pain problems. The present study examined ratings of the expected benefits of CAM (i.e. hypnosis, massage, acupuncture, yoga and relaxation) and conventional medicine (i.e. medications, surgery) interventions in 45 children (32 girls; mean age = 13.8 years +/- 2.5) and parents (39 mothers) presenting for treatment at a specialty clinic for chronic pediatric pain. Among children, medications and relaxation were expected to be significantly more helpful than the remaining approaches (P CAM to be fairly low with parents' expectations only somewhat more positive. The current findings suggest that educational efforts directed at enhancing treatment expectations regarding CAM, particularly among children with chronic pain, are warranted.

Luís de Camões - O Lírico

Directory of Open Access Journals (Sweden)

Sigismundo Spina

1953-03-01

Full Text Available CIDADE (Hernani. - Luís de Camões - O Lírico . Livraria Bertrand, Lisboa, 1952. 354 pp. (Primeiro Parágrafo do Artigo Os estudos da obra lírica de Camões levados a efeito pela erudição de Hernani Cidade datam de quase 20 anos, quando em 1936, na "Revista da Faculdade de Lisboa", escreveu "LUIS DE CAMÕES" - o Lírico.

The role of complementary and alternative medicine (CAM in Germany – A focus group study of GPs

Directory of Open Access Journals (Sweden)

Rosemann Thomas

2008-06-01

Full Text Available Abstract Background There has been a marked increase in the use of complementary and alternative medicine (CAM in recent years worldwide. In Germany, apart from 'Heilpraktiker' (= state-licensed, non-medical CAM practitioners, some general practitioners (GPs provide CAM in their practices. This paper aims to explore the attitudes of GPs about the role of CAM in Germany, in relation to the healthcare system, quality of care, medical education and research. Furthermore, experiences of GPs integrating CAM in their daily practice were explored. Methods Using a qualitative methodological approach 3 focus groups with a convenience sample of 17 GPs were conducted. The discussions were transcribed verbatim and analysed using qualitative content analysis. Results The majority of the participating GPs had integrated one or more CAM therapies into their every-day practice. Four key themes were identified based on the topics covered in the focus groups: the role of CAM within the German healthcare system, quality of care, education and research. Within the theme 'role of CAM within the healthcare system' there were five categories: integration of CAM, CAM in the Statutory Health Insurance, modernisation of the Statutory Health Insurance Act, individual healthcare services and 'Heilpraktiker'. Regarding quality of care there were two broad groups of GPs: those who thought patients would benefit from standardizing CAM and those who feared that quality control would interfere with the individual approach of CAM. The main issues identified relating to research and education were the need for the development of alternative research strategies and the low quality of existing CAM education respectively. Conclusion The majority of the participating GPs considered CAM as a reasonable complementary approach within primary care. The study increased our understanding of GPs attitudes about the role of CAM within the German healthcare system and the use of

Cam Femoroacetabular Impingement as a Possible Explanation of Recalcitrant Anterior Knee Pain.

Science.gov (United States)

Sanchis-Alfonso, Vicente; Tey, Marc; Monllau, Joan Carles

2016-01-01

We present a case of a patient with chronic anterior knee pain (AKP) recalcitrant to conservative treatment who returned to our office for severe hip pain secondary to Cam femoroacetabular impingement (Cam FAI) at 10 months after the onset of knee pain. This case highlights the fact that the main problem is not in the patella but in the hip in some patients with AKP. We hypothesize that there is an external femoral rotation in order to avoid the impingement and therefore the hip pain in patients with Cam FAI. This functional femoral rotation could provoke a patellofemoral imbalance that may be, in theory, responsible for patellofemoral pain in this particular patient. In our case, Cam FAI resolution was related to the resolution of AKP.

Fabricating Complete Dentures with CAD/CAM and RP Technologies.

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Bilgin, Mehmet Selim; Erdem, Ali; Aglarci, Osman Sami; Dilber, Erhan

2015-06-01

Two techological approaches for fabricating dentures; computer-aided design and computer-aided manufacturing (CAD/CAM) and rapid prototyping (RP), are combined with the conventional techniques of impression and jaw relation recording to determine their feasibility and applicability. Maxillary and mandibular edentulous jaw models were produced using silicone molds. After obtaining a gypsum working model, acrylic bases were crafted, and occlusal rims for each model were fabricated with previously determined standard vertical and centric relationships. The maxillary and mandibular relationships were recorded with guides. The occlusal rims were then scanned with a digital scanner. The alignment of the maxillary and mandibular teeth was verified. The teeth in each arch were fabricated in one piece, or set, either by CAM or RP. Conventional waxing and flasking was then performed for both methods. These techniques obviate a practitioner's need for technicians during design and provide the patient with an opportunity to participate in esthetic design with the dentist. In addition, CAD/CAM and RP reduce chair time; however, the materials and techniques need further improvements. Both CAD/CAM and RP techniques seem promising for reducing chair time and allowing the patient to participate in esthetics design. Furthermore, the one-set aligned artificial tooth design may increase the acrylic's durability. © 2015 by the American College of Prosthodontists.

A CAD-CAM prosthodontic option and gingival zenith position for a rotated maxillary right central incisor: An evaluation

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Mukesh Singhal

2012-01-01

Conclusion: Digital imaging provides an immediate treatment option for the patients. Software also provides an interim aid, for the clinician as well as technician, in the form of two-dimensional photographs. CAD-CAM is entirely a helping instrument against the conservative prosthetic options and gingival zenith position for a rotated central incisor. It helps in patient education and in motivation.

Epigenetic regulation of L1CAM in endometrial carcinoma: comparison to cancer–testis (CT-X) antigens

International Nuclear Information System (INIS)

Schirmer, Uwe; Fiegl, Heidi; Pfeifer, Marco; Zeimet, Alain G; Müller-Holzner, Elisabeth; Bode, Peter K; Tischler, Verena; Altevogt, Peter

2013-01-01

L1CAM was originally identified as an adhesion molecule involved in neural development. In many human carcinomas L1CAM is over-expressed and is associated with a bad prognosis. We previously reported that L1CAM was absent in the vast majority of endometrioid endometrial carcinomas (ECs) (type 1) but was strongly expressed in the more aggressive serous and clear-cell ECs (termed type 2). The differential regulation of L1CAM in ECs is not well understood. Recent evidence suggests that it can be regulated by epigenetic mechanisms. Here we investigated the role of DNA-methylation of the L1CAM promoter for expression. We also studied the relationship to cancer testis (CT-X) antigens that co-localize with L1CAM on chromosome Xq28, a region that is often activated in human tumors. We used EC cell lines and primary tumor tissues for our analysis. For expression analysis we employed RT-PCR and Western blotting. DNA-Methylation of the L1CAM promoter was determined after bisulfite conversation and DNA sequencing. Tumor tissues were examined by immunohistochemical (IHC) staining. We demonstrate that the treatment of L1CAM low/negative expressing EC cell lines with 5 ′ -Azacytidine (5-AzaC) or knock-down of DNMT1 (DNA methyltransferase 1) as well as the HDAC (histone deacetylase) inhibitor Trichostatin A (TSA) up-regulated L1CAM at the mRNA and protein level. The L1CAM gene has two promoter regions with two distinct CpG islands. We observed that the expression of L1CAM correlated with hypermethylation in promoter 1 and 5-AzaC treatment affected the DNA-methylation pattern in this region. The CT-X antigens NY-ESO-1, MAGE-A3 and MAGE-A4 were also strongly up-regulated by 5-AzaC or knock-down of DNMT1 but did not respond to treatment with TSA. Primary EC tumor tissues showed a variable methylation pattern of the L1CAM promoter. No striking differences in promoter methylation were observed between tumor areas with L1CAM expression and those without expression. L1CAM expression

Complementing a Rural Pharmacy Course with CAM: Reflections from a Decade of Experience

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Maree Simpson

2014-03-01

Full Text Available Substantial complementary medicines (CAM use is reported worldwide. Australian consumers use CAM for health maintenance, minor self-limiting disease states, and also for chronic conditions. The increasing use of CAM has required pharmacists to become increasingly more knowledgeable about CAM and the ethics of CAM recommendation. When the first Australian non-metropolitan pharmacy program was started at Charles Sturt University, in 1997, it was decided to incorporate two innovative courses to assist rurally educated students to engage with health consumers who expect pharmacists to be able to assist them with CAM. This discussion traces and reflects on the development, implementation and current situation of the Complementary Medicines for Pharmacy course. Over time, this course has evolved from a final year elective with a focus on familiarization to a mandated course with a phytomedicine focus to an integrated topic in final year with a focus on evidence, quality of evidence and professional decision-making demonstrated in a reflective professional portfolio. Of potentially greater importance, however, has been the introduction of complementary medicines as a topic in every year of the course with the goal of facilitating effective professional engagement with health consumers.

Evaluation of mechanical and optical behavior of current esthetic dental restorative CAD/CAM composites.

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Stawarczyk, Bogna; Liebermann, Anja; Eichberger, Marlis; Güth, Jan-Frederik

2015-03-01

To determine the mechanical and optical properties of CAD/CAM composites (LAVA Ultimate, Cerasmart, Shofu Block and two exp. CAD/CAM composites), a hybrid material (VITA Enamic), a leucite (IPS Empress CAD) and a lithium disilicate glass-ceramic (IPS e.max CAD). Three-point flexural strength (FS) was investigated according ISO 6872:2008 (N=240/n=30). Two-body wear (TBW) was analyzed in a chewing simulator (1,200,000 cycles, 50N, 5°/55°C) using human teeth as antagonists (N=120/n=15). Quantitative analysis of wear was carried out with a 3D-scanner and associated matching software. Discoloration rate (DR) after 14 days of storage in cress, curry, red wine, and distilled water (N=384/n=12), and translucency (T) (N=384/n=48) of CAD/CAM materials were measured in a spectrophotometer (400-700nm wavelength). Data were analyzed using two-/one-way ANOVA with Scheffé post-hoc test, Kruskal-Wallis-H test, and linear mixed models (α=0.05). IPS e.max CAD showed the highest FS (pCAD/CAM composites (exception: Shofu Block). The lowest FS showed VITA Enamic and IPS Empress CAD (pCAD, VITA Enamic, exp. CAD/CAM composite 2, followed by IPS e.max presented lower material TBW than the remaining CAD/CAM materials (pcurry>cress>distilled water) exerted the highest influence on DR (pCAD/CAM material. Glass-ceramics showed lower DR than CAD/CAM composites (pCAD/CAM composites presented moderate FS, high T and antagonist friendly behavior. Glass-ceramic demonstrated the most favorable DR and lowest TBW on the material side. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Pleiotropic Role of L1CAM in Tumor Vasculature

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Francesca Angiolini

2017-01-01

Full Text Available Angiogenesis, the formation of new vessels, is a key step in the development, invasion, and dissemination of solid tumors and, therefore, represents a viable target in the context of antitumor therapy. Indeed, antiangiogenic approaches have given promising results in preclinical models and entered the clinical practice. However, in patients, the results obtained so far with antiangiogenic drugs have not completely fulfilled expectations, especially because their effect has been transient with tumors developing resistance and evasion mechanisms. A better understanding of the mechanisms that underlie tumor vascularization and the functional regulation of cancer vessels is a prerequisite for the development of novel and alternative antiangiogenic treatments. The L1 cell adhesion molecule (L1CAM, a cell surface glycoprotein previously implicated in the development and plasticity of the nervous system, is aberrantly expressed in the vasculature of various cancer types. L1CAM plays multiple pro-angiogenic roles in the endothelial cells of tumor-associated vessels, thus emerging as a potential therapeutic target. In addition, L1CAM prevents the maturation of cancer vasculature and its inhibition promotes vessel normalization, a process that is thought to improve the therapeutic response of tumors to cytotoxic drugs. We here provide an overview on tumor angiogenesis and antiangiogenic therapies and summarize the current knowledge on the biological role of L1CAM in cancer vasculature. Finally, we highlight the clinical implications of targeting L1CAM as a novel antiangiogenic and vessel-normalizing approach.

Disclosure of Complementary and Alternative Medicine to Conventional Medical Providers: Variation by Race/Ethnicity and Type of CAM

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Chao, Maria T.; Wade, Christine; Kronenberg, Fredi

2009-01-01

Background Complementary and alternative medicine (CAM) is often used alongside conventional medical care, yet fewer than half of patients disclose CAM use to medical doctors. CAM disclosure is particularly low among racial/ethnic minorities, but reasons for differences, such as type of CAM used or quality of conventional healthcare, have not been explored. Objective We tested the hypotheses that disclosure of CAM use to medical doctors is higher for provider-based CAM and among non-Hispanic whites, and that access to and quality of conventional medical care account for racial/ethnic differences in CAM disclosure. Methods Bivariate and multiple variable analyses of the 2002 National Health Interview Survey and 2001 Health Care Quality Survey were performed. Results Disclosure of CAM use to medical providers was higher for provider-based than self-care CAM. Disclosure of any CAM was associated with access to and quality of conventional care and higher among non-Latino whites relative to minorities. Having a regular doctor and quality patient–provider relationship mitigated racial/ethnic differences in CAM disclosure. Conclusion Insufficient disclosure of CAM use to conventional providers, particularly for self-care practices and among minority populations, represents a serious challenge in medical encounter communications. Efforts to improve disclosure of CAM use should be aimed at improving consistency of care and patient–physician communication across racial/ethnic groups. PMID:19024232

Effects of competition on induction of crassulacean acid metabolism in a facultative CAM plant.

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Yu, Kailiang; D'Odorico, Paolo; Li, Wei; He, Yongli

2017-06-01

Abiotic drivers of environmental stress have been found to induce CAM expression (nocturnal carboxylation) in facultative CAM species such as Mesembryanthemum crystallinum. The role played by biotic factors such as competition with non-CAM species in affecting CAM expression, however, remains largely understudied. This research investigated the effects of salt and water conditions on the competition between M. crystallinum and the C 3 grass Bromus mollis with which it is found to coexist in California's coastal grasslands. We also investigated the extent to which CAM expression in M. crystallinum was affected by the intensity of the competition with B. mollis. We found that M. crystallinum had a competitive advantage over B. mollis in drought and saline conditions, while B. mollis exerted strong competitive effects on M. crystallinum in access to light and soil nutrients in high water conditions. This strong competitive effect even outweighed the favorable effects of salt or water additions in increasing the biomass and productivity of M. crystallinum in mixture. Regardless of salt conditions, M. crystallinum did not switch to CAM photosynthesis in response to this strong competitive effect from B. mollis. Disturbance (i.e., grass cutting) reduced the competitive pressure by B. mollis and allowed for CAM expression in M. crystallinum when it was grown mixed with B. mollis. We suggest that moderate competition with other functional groups can enhance CAM expression in M. crystallinum, thereby affecting its plasticity and ability to cope with biological stress.

Cam Femoroacetabular Impingement as a Possible Explanation of Recalcitrant Anterior Knee Pain

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Vicente Sanchis-Alfonso

2016-01-01

Full Text Available We present a case of a patient with chronic anterior knee pain (AKP recalcitrant to conservative treatment who returned to our office for severe hip pain secondary to Cam femoroacetabular impingement (Cam FAI at 10 months after the onset of knee pain. This case highlights the fact that the main problem is not in the patella but in the hip in some patients with AKP. We hypothesize that there is an external femoral rotation in order to avoid the impingement and therefore the hip pain in patients with Cam FAI. This functional femoral rotation could provoke a patellofemoral imbalance that may be, in theory, responsible for patellofemoral pain in this particular patient. In our case, Cam FAI resolution was related to the resolution of AKP.

Bone Reduction to Facilitate Immediate Implant Placement and Loading Using CAD/CAM Surgical Guides for Patients With Terminal Dentition.

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Alzoubi, Fawaz; Massoomi, Nima; Nattestad, Anders

2016-10-01

The aim of this study is to present a method, using 3 computer-aided design/computer-aided manufacturing (CAD/CAM) surgical guides, to accurately obtain the desired bone reduction followed by immediate implant placements and loading for patients diagnosed with terminal dentition. Patients who had bone reduction, implants placed, and immediate loading using Anatomage Invivo 5 CAD/CAM surgical guides between the period 2013 and 2015 were evaluated retrospectively. Patients diagnosed with terminal dentition and treated using the "3-guide technique" were identified. Pre- and postsurgical images were superimposed to evaluate deviations of the bone reduction and deviations at the crest, apex, and angle of implants placed. Twenty-six implants placed in 5 patients were included in this study. The overall deviation means measured for bone reduction was 1.98 mm. The overall deviation means measured for implant placement at the crest, apex, and angle were 1.43 mm, 1.90 mm, and 4.14°, respectively. The CAD/CAM surgical guide fabrication is an emerging tool that may facilitate the surgical process and aid in safe and predictable execution of bone reduction and immediate implant placement. Using 3 CAD/CAM surgical guides, a method is presented to obtain the desired bone reduction followed by immediate implant placement and loading for patients diagnosed with terminal dentition. This method may improve guide stability for patients with terminal dentition undergoing complete implant-supported treatment by taking advantage of the teeth to be extracted.

Astrocyte-specific disruption of SynCAM1 signaling results in ADHD-like behavioral manifestations.

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Ursula S Sandau

Full Text Available SynCAM1 is an adhesion molecule involved in synaptic differentiation and organization. SynCAM1 is also expressed in astroglial cells where it mediates astrocyte-to astrocyte and glial-neuronal adhesive communication. In astrocytes, SynCAM1 is functionally linked to erbB4 receptors, which are involved in the control of both neuronal/glial development and mature neuronal and glial function. Here we report that mice carrying a dominant-negative form of SynCAM1 specifically targeted to astrocytes (termed GFAP-DNSynCAM1 mice exhibit disrupted diurnal locomotor activity with enhanced and more frequent episodes of activity than control littermates during the day (when the animals are normally sleeping accompanied by shorter periods of rest. GFAP-DNSynCAM1 mice also display high levels of basal activity in the dark period (the rodent's awake/active time that are attenuated by the psychostimulant D,L-amphetamine, and reduced anxiety levels in response to both avoidable and unavoidable provoking stimuli. These results indicate that disruption of SynCAM1-dependent astroglial function results in behavioral abnormalities similar to those described in animals model of attention-deficit hyperactive disorder (ADHD, and suggest a hitherto unappreciated contribution of glial cells to the pathophysiology of this disorder.

Engineering task plan for rotary mode core sampling exhausters CAM high radiation interlock

International Nuclear Information System (INIS)

BOGER, R.M.

1999-01-01

The Rotary Mode Core Sampling (RMCS) system is primarily made up of the Rotary Mode Core Sample Trucks (RMCST) and the RMCS Exhausters. During RMCS operations an Exhauster is connected to a tank riser and withdraws gases from the tank dome vapor space at approximately 200 Standard Cubic Feet per Minute (SCFM). The gases are passed through two High Efficiency Particulate Air (HEPA) filters before passing out the exhaust stack to the atmosphere. A Continuous Air Monitor (CAM) monitors the exhaust gases in the exhaust stack for beta particle and gamma radiation. The CAM has a high radiation alarm output and a detector fail alarm output. The CAM alarms are currently connected to the data logger only. The CAM alarms require operator response per procedure LMHC 1998 but no automatic functions are initiated by the CAM alarms. Currently, there are three events that can cause an automatic shut down of the Exhauster. These are, Low Tank Pressure, Highnow Stack Flow and High HEPA Filter Differential Pressure (DP)

Three-Dimensional Digital Evaluation of the Fit of Endocrowns Fabricated from Different CAD/CAM Materials.

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Zimmermann, Moritz; Valcanaia, Andre; Neiva, Gisele; Mehl, Albert; Fasbinder, Dennis

2018-03-06

A wide variety of CAD/CAM materials are available for single-tooth restorations. CAD/CAM material characteristics are different and may influence CAM fabrication accuracy. There is no study investigating the influence of different CAD/CAM materials on the final fit of the restoration. The aim of this study was to evaluate the fit of endocrowns fabricated from different CAD/CAM materials using a new 3D evaluation method with an intraoral scanning system. The null hypothesis was that there are no significant differences for the fitting accuracy of different CAD/CAM materials. Preparation for an endocrown was performed on a maxillary right first molar on a typodont, and restorations were fabricated with a chairside CAD/CAM system (CEREC Omnicam, MCXL). Three groups using three different CAD/CAM materials were established (each n = 10): zirconia-reinforced lithium silicate ceramic (Celtra Duo; CD), leucite-reinforced silicate ceramic (Empress CAD; EM), resin nanoceramic (Lava Ultimate; LU). A 3D digital measurement technique (OraCheck, Cyfex AG) using an intraoral scanner (CEREC Omnicam) was used to measure the difference in fit between the three materials for a master endocrown preparation. The preparation scan and the endocrown fit scan were matched with special difference analysis software OraCheck. Three areas were selected for fitting accuracy measurements: margin (MA), axial (AX), occlusal (OC). Statistical analysis was performed using 80% percentile, one-way ANOVA, and post-hoc Scheffé test. Significance level was set to p = 0.05. Results varied from best 88.9 ± 7.7 μm for marginal fit of resin nanoceramic restorations (LU_MA) to worst 182.3 ± 24.0 μm for occlusal fit of zirconia-reinforced lithium silicate restorations (CD_OC). Statistically significant differences were found both within and among the test groups. Group CD performed statistically significantly different from group LU for marginal fit (MA) and axial fit (AX) (p 0.05). Deviation pattern for

CAM and Post-Traumatic Stress Disorder

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Alex Hankey

2007-01-01

Full Text Available In the form of the Transcendental Meditation program CAM offers a method of eliminating deep-rooted stress, the efficacy of which has been demonstrated in several related studies. Any discussion of CAM and post-traumatic stress disorder should include a study of its application to Vietnam War Veterans in which improvements were observed on all variables, and several participants were able to return to work after several years of being unable to hold a job. The intervention has been studied for its impact on brain and autonomic nervous system function. It has been found to be highly effective against other stress-related conditions such as hypertension, and to improve brain coherence—a measure of effective brain function. It should be considered a possible ‘new and improved mode of treatment’ for PTSD, and further studies of its application made.

Camões e Garret: navegações do Restelo a Cascais

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Paulo Motta Oliveira

1999-10-01

Full Text Available Esse ensaio pretende analisar a presença de Luís de Camões, em especialdo Camões épico, em algumas das principais obras de Almeida Garrett, mostrando que essa presença faz uma navegação que partindo de Restelo chega a Cascais.

Near-infrared imaging survey of faint companions around young dwarfs in the Pleiades cluster

International Nuclear Information System (INIS)

Itoh, Yoichi; Funayama, Hitoshi; Hashiguchi, Toshio; Oasa, Yumiko; Hayashi, Masahiko; Fukagawa, Misato; Currie, Thayne

2011-01-01

We conducted a near-infrared imaging survey of 11 young dwarfs in the Pleiades cluster using the Subaru Telescope and the near-infrared coronagraph imager. We found ten faint point sources, with magnitudes as faint as 20 mag in the K-band, with around seven dwarfs. Comparison with the Spitzer archive images revealed that a pair of the faint sources around V 1171 Tau is very red in infrared wavelengths, which indicates very low-mass young stellar objects. However, the results of our follow-up proper motion measurements implied that the central star and the faint sources do not share common proper motions, suggesting that they are not physically associated.

Marginal and internal fit of nano-composite CAD/CAM restorations

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So-Hyun Park

2016-02-01

Full Text Available Objectives The purpose of this study was to compare the marginal and internal fit of nano-composite CAD-CAM restorations. Materials and Methods A full veneer crown and an mesio-occluso-distal (MOD inlay cavity, which were prepared on extracted human molars, were used as templates of epoxy resin replicas. The prepared teeth were scanned and CAD-CAM restorations were milled using Lava Ultimate (LU and experimental nano-composite CAD/CAM blocks (EB under the same milling parameters. To assess the marginal and internal fit, the restorations were cemented to replicas and were embedded in an acrylic mold for sectioning at 0.5 mm intervals. The measured gap data were pooled according to the block types and measuring points for statistical analysis. Results Both the block type and measuring point significantly affected gap values, and their interaction was significant (p = 0.000. In crowns and inlays made from the two blocks, gap values were significantly larger in the occlusal area than in the axial area, while gap values in the marginal area were smallest (p < 0.001. Among the blocks, the restorations milled from EB had a significantly larger gap at all measuring points than those milled from LU (p = 0.000. Conclusions The marginal and internal gaps of the two nano-composite CAD/CAM blocks differed according to the measuring points. Among the internal area of the two nano-composite CAD/CAM restorations, occlusal gap data were significantly larger than axial gap data. The EB crowns and inlays had significantly larger gaps than LU restorations.

CAM: A Collaborative Object Memory System

NARCIS (Netherlands)

Vyas, Dhaval; Nijholt, Antinus; Kröner, Alexander

2010-01-01

Physical design objects such as sketches, drawings, collages, storyboards and models play an important role in supporting communication and coordination in design studios. CAM (Cooperative Artefact Memory) is a mobile-tagging based messaging system that allows designers to collaboratively store

miR-21-3p is a positive regulator of L1CAM in several human carcinomas.

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Doberstein, Kai; Bretz, Niko P; Schirmer, Uwe; Fiegl, Heidi; Blaheta, Roman; Breunig, Christian; Müller-Holzner, Elisabeth; Reimer, Dan; Zeimet, Alain G; Altevogt, Peter

2014-11-28

Expression of L1 cell adhesion molecule (L1CAM) occurs frequently in human cancers and is associated with poor prognosis in cancers such as ovarian, endometrial, breast, renal cell carcinoma and pancreatic ductal adenocarcinoma. L1CAM promotes cell motility, invasion, chemoresistance and metastasis formation. Elucidating genetic processes involved in the expression of L1CAM in cancers is of considerable importance. Transcription factors such as SLUG, β-catenin/TCF-LEF, PAX8 and VHL have been implicated in the re-activation of L1CAM in various types of cancers. There is increasing evidence that micro-RNAs can also have strong effects on gene expression. Here we have identified miR-21-3p as a positive regulator of L1CAM expression. Over-expression of miR-21-3p (miR-21*) but not the complementary sequence miR-21-5p (miR-21) could strongly augment L1CAM expression in renal, endometrial and ovarian carcinoma derived cell lines by an unknown mechanism involving transcriptional activation of the L1CAM gene. In patient cohorts from renal, endometrial and ovarian cancers we observed a strong positive correlation of L1CAM and miR-21-3p expressions. Although L1CAM alone was a reliable marker for overall and disease free survival, the combination of L1CAM and miR-21-3p expressions strongly enhanced the predictive power. Our findings shed new light on the complex regulation of L1CAM in cancers and advocate the use of L1CAM/miR-21-3p for diagnostic application. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Effect of degradative plasmid CAM-OCT on responses of Pseudomonas bacteria to UV light

International Nuclear Information System (INIS)

McBeth, D.L.

1989-01-01

The effect of plasmid CAM-OCT on responses to UV irradiation was compared in Pseudomonas aeruginosa, in Pseudomonas putida, and in Pseudomonas putida mutants carrying mutations in UV response genes. CAM-OCT substantially increased both survival and mutagenesis in the two species. P. aeruginosa strains without CAM-OCT exhibited much higher UV sensitivity than did P. putida strains. UV-induced mutagenesis of plasmid-free P. putida was easily detected in three different assays (two reversion assays and one forward mutation assay), whereas UV mutagenesis of P. aeruginosa without CAM-OCT was seen only in the forward mutation assay. These results suggest major differences in DNA repair between the two species and highlight the presence of error-prone repair functions on CAM-OCT. A number of P. putida mutants carrying chromosomal mutations affecting either survival or mutagenesis after UV irradiation were isolated, and the effect of CAM-OCT on these mutants was determined. All mutations producing a UV-sensitive phenotype in P. putida were fully suppressed by the plasmid, whereas the plasmid had a more variable effect on mutagenesis mutations, suppressing some and producing no suppression of others. On the basis of the results reported here and results obtained by others with plasmids carrying UV response genes, it appears that CAM-OCT may differ either in regulation or in the number and functions of UV response genes encoded

INTEGRASI SOFTWARE CAD-CAM DALAM SISTEM OPERASI MESIN BUBUT CNC

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Yuris Setyoadi

2015-12-01

Full Text Available Computer Aided Manufacturing (CAM adalah sebuah teknologi aplikasi yang menggunakan perangkat lunak komputer dan mesin untuk memfasilitasi dan mengotomatisasi proses manufaktur. Computer Aided Manufacturing (CAM adalah penerus dari Computer Aided Engineering (CAE dan sering digunakan bersama dengan Computer-Aided Design (CAD. Bidang manufaktur, perangkat komputer telah dipergunakan untuk mengontrol mesin-mesin produksi otomatis dengan ketepatan tinggi, misalnya mesin CNC. ?é?áArtikel ini membahas tentang penggunaan software CAD-CAM (SOLIDWorks dan CAMWorks yang terintegrasi kemudian diaplikasikan ke mesin bubut CNC yang menggunakan software Mach3, Mach3 adalah software yang bisa mengubah komputer dekstop menjadi sebuah piranti kontroller mesin CNC. Software SOLIDWorks, CAMWorks dan Mach3 diintegrasikan ke dalam sistem operasi mesin bubut CNC sehingga proses koreksi dan modifikasi format perintah gerakan dalam G/M code dapat dilakukan dalam software tersebut.

Performance of CAD/CAM fabricated fiber posts in oval-shaped root canals: An in vitro study.

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Tsintsadze, Nino; Juloski, Jelena; Carrabba, Michele; Tricarico, Marella; Goracci, Cecilia; Vichi, Alessandro; Ferrari, Marco; Grandini, Simone

2017-10-01

To assess the push-out strength, the cement layer thickness and the interfacial nanoleakage of prefabricated fiber posts, CAD/CAM fiber posts and metal cast posts cemented into oval-shaped root canals. Oval-shaped post spaces were prepared in 30 single-rooted premolars. Roots were randomly assigned to three groups (n=10), according to the post type to be inserted: Group 1: Prefabricated fiber post (D.T. Light-Post X-RO Illusion); Group 2: Cast metal post; Group 3: CAD/CAM-fabricated fiber post (experimental fiber blocks). In Group 3, post spaces were sprayed with scan powder (VITA), scanned with an inEos 4.2 scanner, and fiber posts were milled using an inLab MC XL CAD/CAM milling unit. All posts were cemented using Gradia Core dual-cure resin cement in combination with Gradia core self-etching bond (GC). After 24 hours, the specimens were sectioned perpendicular to the long axis into six 1 mm-thick sections, which were differentiated by the root level. Sections from six roots per group were used to measure the cement thickness and subsequently for the thin-slice push-out test, whereas the sections from the remaining four teeth were assigned to interfacial nanoleakage test. The cement thickness around the posts was measured in micrometers (µm) on the digital images acquired with a digital microscope using the Digimizer software. Thin-slice push-out test was conducted using a universal testing machine at the crosshead speed of 0.5 mm/minute and the bond strength was expressed in megaPascals (MPa). The interfacial nanoleakage was observed under light microscope and quantified by scoring the depth of silver nitrate penetration along the post-cement-dentin interfaces. The obtained results were statistically analyzed by Kruskal-Wallis ANOVA, followed by the Dunn's Multiple Range test for post hoc comparisons. The level of significance was set at PCAD/CAM-fabricated fiber posts achieved retention that was comparable to that of cast metal posts and significantly higher

Edge strength of CAD/CAM materials.

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Pfeilschifter, Maria; Preis, Verena; Behr, Michael; Rosentritt, Martin

2018-05-16

To investigate the edge force of CAD/CAM materials as a function of (a) material, (b) thickness, and (c) distance from the margin. Materials intended for processing with CAD/CAM were investigated: eight resin composites, one resin-infiltrated ceramic, and a clinically proven lithiumdisilicate ceramic (reference). To measure edge force (that is, load to failure/crack), plates (d = 1 mm) were fixed and loaded with a Vickers diamond indenter (1 mm/min, Zwick 1446) at a distance of 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, and 1.0 mm from the edge. Edge force was defined as a loading force at a distance of 0.5 mm. The type of failure was determined. To investigate the influence of the thickness, all data were determined on 1-mm and 2-mm plates. To test the influence of bonding and an underlying dentin, individual 1-mm plates were bonded to a 1-mm-thick dentin-like (concerning modulus of elasticity) resin composite. For the 1-mm plates, edge force varied between 64.4 ± 24.2 N (Shofu Block HC) and 183.2 ± 63.3 N (ceramic reference), with significant (p ≤ 0.001) differences between the materials. For the 2-mm plates, values between 129.2 ± 32.5 N (Lava Ultimate) and 230.3 ± 67.5 N (Cerasmart) were found. Statistical comparison revealed no significant differences (p > 0.109) between the materials. Brilliant Crios (p = 0.023), Enamic (p = 0.000), Shofu Blocks HC (p = 0.009), and Grandio Bloc (p = 0.002) showed significantly different edge force between the 1-mm- and 2-mm-thick plates. The failure pattern was either cracking, (severe) chipping, or fracture. Material, material thickness, and distance from the edge impact the edge force of CAD/CAM materials. CAD/CAM materials should be carefully selected on the basis of their individual edge force and performance during milling. Copyright © 2018 Elsevier Ltd. All rights reserved.

A systematic review of the traits and cognitions associated with use of and belief in complementary and alternative medicine (CAM).

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Galbraith, Niall; Moss, Tim; Galbraith, Victoria; Purewal, Satvinder

2018-08-01

Complementary and alternative medicine (CAM) use is widespread despite the controversy over its effectiveness. Although previous reviews have examined the demographics and attitudes of CAM users, there is no existing review on the traits or cognitions which characterise either CAM users or those who believe in CAM effectiveness. The current systematic review set out to address these gaps in the literature by applying a narrative synthesis. A bibliographic search and manual searches were undertaken and key authors were contacted. Twenty-three papers were selected. The trait openness to experience was positively associated with CAM use but not CAM belief. Absorption and various types of coping were also positively associated with CAM use and belief. No other trait was reliably associated with CAM use or belief. Intuitive thinking and ontological confusions were positively associated with belief in CAM effectiveness; intuitive thinking was also positively associated with CAM use. Studies researching cognitions in CAM use/belief were mostly on non-clinical samples, whilst studies on traits and CAM use/belief were mostly on patients. The quality of studies varied but unrepresentative samples, untested outcome measures and simplistic statistical analyses were the most common flaws. Traits and cognition might be important correlates of CAM use and also of faith in CAM.

Complete Dentures Fabricated with CAD/CAM Technology and a Traditional Clinical Recording Method.

Science.gov (United States)

Janeva, Nadica; Kovacevska, Gordana; Janev, Edvard

2017-10-15

The introduction of computer-aided design/computer-aided manufacturing (CAD/CAM) technology into complete denture (CD) fabrication ushered in a new era in removable prosthodontics. Commercially available CAD/CAM denture systems are expected to improve upon the disadvantages associated with conventional fabrication. The purpose of this report is to present the workflow involved in fabricating a CD with a traditional clinical recording method and CAD/CAM technology and to summarize the advantages to the dental practitioner and the patient.

Search for rapid variability of 53 Cam

International Nuclear Information System (INIS)

Zverko, J.

1982-01-01

Photoelectric observations of magnetic Ap star 53 Cam made at the Skalnate Pleso Observatory in 1978 and 1979 are analyzed from the point of view of rapid variability. The observations were made with an intermediate passband filter, effective wavelength 526 nm. Besides the differences msub(53Cam)-msub(Comp), the behaviour was also investigated of the deflections for the comparison star during the observation runs. A strong correlation between the behaviour of the comparison and variable star light curve was found and the appearance differs from night to night depending on atmospheric conditions. Each observation run is analyzed in detail and it was concluded that all observed variations are only apparent and due to the variability of atmospheric extinction above the observation site. (author)

CLIC main beam quadrupole active pre-alignment based on cam movers

CERN Document Server

Kemppinen, J; Leuxe, R; Mainaud Durand, H; Sandomierski, J; Sosin, M

2012-01-01

Compact Linear Collider (CLIC) is a study for a future 48 km long linear electron-positron collider in the multi TeV range. Its target luminosity can only be reached if the main beam quadrupoles (MB quads) are actively pre-aligned within 17 µm in sliding windows of 200 m with respect to a straight reference line. In addition to the positioning requirement, the pre-alignment system has to provide a rigid support for the nano-stabilization system to ensure that the first eigenfrequency is above 100 Hz. Re-adjustment based on cam movers was chosen for detailed studies to meet the stringent pre-alignment requirements. There are four different types of MB quads in CLIC. Their lengths and masses vary so that at least two types of cam movers have to be developed. The validation of the cams with less stringent space restrictions has proceeded to a test setup in 5 degrees of freedom (DOF). Prototypes of the more demanding, smaller cams have been manufactured and they are under tests in 1 DOF. This paper describes the...

A Unique Opportunity for an Intercultural Discussion on CAM and Liver Disease

Directory of Open Access Journals (Sweden)

Francesco Marotta

2005-01-01

Full Text Available The meeting of the APASL, Asian Pacific Association for the Study of the Liver, was held in December 2004, in New Delhi, India. The meeting was held under the patronage of the APASL Committee and Board of Presidents of the National Liver Association and in conjunction with the annual conference of the Indian Association for the Study of Liver (INASL. The congress was designed to have a core meeting with three parallel sessions running throughout, dedicated research workshops and intensive breakfast sessions. This report concentrates on the two sessions devoted to complementary and alternative medicine (CAM and shows the latest research in CAM for liver disease and the concerns of doctors about integrating CAM with more traditional treatments. With researchers and practitioners gathering from all over the world, it was a unique opportunity for an intercultural discussion on CAM and liver disease.

PreCam: A Precursor Observational Campaign for Calibration of the Dark Energy Survey

Energy Technology Data Exchange (ETDEWEB)

Kuehn, K.; Kuhlmann, S.; Allam, S.; Annis, J. T.; Bailey, T.; Balbinot, E.; Bernstein, J. P.; Biesiadzinski, T.; Burke, D. L.; Butner, M.; Camargo, J. I. B.; da Costa, L. A. N.; DePoy, D.; Diehl, H. T.; Dietrich, J. P.; Estrada, J.; Fausti, A.; Gerke, B.; Guarino, V.; Head, H. H.; Kessler, R.; Lin, H.; Lorenzon, W.; Maia, M. A. G.; Maki, L.; Marshall, J.; Nord, B.; Neilsen, E.; Ogando, R. L. C.; Park, D.; Peoples, J.; Rastawicki, D.; Rheault, J. -P.; Santiago, B.; Schubnell, M.; Seitzer, P.; Smith, J. A.; Spinka, H.; Sypniewski, A.; Tarle, G.; Tucker, D. L.; Walker, A. R.; Wester, W.

2013-04-01

PreCam, a precursor observational campaign supporting the Dark Energy Survey (DES), is designed to produce a photometric and astrometric catalog of nearly a hundred thousand standard stars within the DES footprint, while the PreCam instrument also serves as a prototype testbed for the Dark Energy Camera's hardware and software. This catalog represents a potential 100-fold increase in Southern Hemisphere photometric standard stars, and therefore will be an important component in the calibration of the Dark Energy Survey. We provide details on the PreCam instrument's design, construction, and testing, as well as results from a subset of the 51 nights of PreCam survey observations on the University of Michigan Department of Astronomy's Curtis-Schmidt telescope at Cerro Tololo Inter-American Observatory (CTIO). We briefly describe the preliminary data processing pipeline that has been developed for PreCam data and the preliminary results of the instrument performance, as well as astrometry and photometry of a sample of stars previously included in other southern sky surveys.

Initiating a Reiki or CAM program in a healthcare organization--developing a business plan.

Science.gov (United States)

Vitale, Anne

2014-01-01

Complementary and alternative medicine (CAM) services, such as Reiki, continue to be offered to consumers in many hospitals and other health care organizations. There is growing interest among nurses, doctors, and other health care providers for the integration of CAM therapies into traditional settings. Health care organizations are responding to this need but may not know how to start CAM programs. Starting a Reiki program in a health care setting must be envisioned in a business model approach. This article introduces nurses and other health care providers to the basic concepts of business plan development and important steps to follow when starting a Reiki or CAM program.

Types and sociodemographic correlates of complementary and alternative medicine (CAM) use among people with epilepsy in Oman.

Science.gov (United States)

Al Asmi, Abdullah; Al Maniri, Abdullah; Al-Farsi, Yahya M; Burke, David T; Al Asfoor, Fatema M H; Al Busaidi, Ibrahim; Al Breiki, Mohamed H A; Lahiri, Shaon; Braidy, Nady; Essa, Musthafa M; Al-Adawi, Samir

2013-11-01

Nonpharmacological treatment strategies that originate from sociocultural teachings and are beyond the scope of allopathic medicine are commonly used among people with epilepsy (PWE) in many parts of the world. The present study explored the types and sociodemographic correlates of complementary and alternative medicine (CAM) use among PWE in Oman among attendees of a neurological unit at a tertiary care center. Data on the types of CAM were gathered from telephone interviews. The relevant demographic and clinical characteristics of the participants were obtained from electronic medical records. Of the total of 101 participants, 73.3% were CAM users. The majority of these participants have not disclosed their CAM use to their allopathic health-care providers. The most common types of CAM reported were those falling under the 'mind-body' type (incantations and fumigation) and biologically based (herbal concoctions) or a combination of them. Compared to non-CAM users, a significant and greater proportion of CAM users attributed the etiology of their illness to nonbiomedical factors such as 'evil eyes' (P=0.04). The multivariate logistic regression model indicated that the use of CAM was highly associated with age of Oman. The most utilized type of CAM falls under the umbrella of mind-body practice. © 2013 Elsevier Inc. All rights reserved.

Community asset mapping, mobilisation and management (CA/M) approach: a case study

CSIR Research Space (South Africa)

Saidi, MEM

2006-03-01

Full Text Available by the community. The paper will present a practical application and recommendations based on a CA/M implementation in the Imperani Tourism and Training Centre (ITTC) project in Ficksburg. The ITTC experience has contributed to the development of a CA/M Guideline...

Position paper -- Continuous air monitor (CAM) acquisition recommendation

International Nuclear Information System (INIS)

Hughes, M.E.

1995-01-01

The purpose of this position paper is to document the decision not to acquire continuous air monitors (CAM's) from government excess/surplus supplies. The procurement plan for equipment to be acquired for project W-236A, the Multi-Function Waste Tank Facility (MWTF), stipulates that radiation monitoring equipment will be supplied by WHC via the stock retained within the excess/surplus inventory or utilization of procured instruments from canceled projects. Technological advances within the radiation detection industry have ultimately outdated the instruments that are available within the excess/surplus stock. These machines represent the technology of the 1970's era. The CAM models in use or within the excess/surplus supplies are obsolete and have been discontinued by the manufacturer. Therefore, the majority of the excess/surplus CAM's are being reacquired and disassembled by instrument shops for in-house acquisition of spare parts for the instruments that are still presently in-service. It is being recommended by W-236A projects department that the strategy to acquire surplus/excess radiation monitoring devices be modified. The recommendation is to directly procure instruments that are equal to the technology available within this industry

Discoloration of various CAD/CAM blocks after immersion in coffee

Directory of Open Access Journals (Sweden)

Sasipin Lauvahutanon

2017-02-01

Full Text Available Objectives This study evaluated color differences (ΔEs and translucency parameter changes (ΔTPs of various computer-aided design/computer-aided manufacturing (CAD/CAM blocks after immersion in coffee. Materials and Methods Eight CAD/CAM blocks and four restorative composite resins were evaluated. The CIE L*a*b* values of 2.0 mm thick disk-shaped specimens were measured using the spectrophotometer on white and black backgrounds (n = 6. The ΔEs and ΔTPs of one day, one week, and one month immersion in coffee or water were calculated. The values of each material were analyzed by two-way ANOVA and Tukey's multiple comparisons (α = 0.05. The ΔEs after prophylaxis paste polishing of 1 month coffee immersion specimens, water sorption and solubility were also evaluated. Results After one month in coffee, ΔEs of CAD/CAM composite resin blocks and restorative composites ranged from 1.6 to 3.7 and from 2.1 to 7.9, respectively, and ΔTPs decreased. The ANOVA of ΔEs and ΔTPs revealed significant differences in two main factors, immersion periods and media, and their interaction except for ΔEs of TEL (Telio CAD, Ivoclar Vivadent. The ΔEs significantly decreased after prophylaxis polishing except GRA (Gradia Block, GC. There was no significant correlation between ΔEs and water sorption or solubility in water. Conclusions The ΔEs of CAD/CAM blocks after immersion in coffee varied among products and were comparable to those of restorative composite resins. The discoloration of CAD/CAM composite resin blocks could be effectively removed with prophylaxis paste polishing, while that of some restorative composites could not be removed.

Influence of Different CAM Strategies on the Fit of Partial Crown Restorations: A Digital Three-dimensional Evaluation.

Science.gov (United States)

Zimmermann, M; Valcanaia, A; Neiva, G; Mehl, A; Fasbinder, D

2018-04-09

CAM fabrication is an important step within the CAD/CAM process. The internal fit of restorations is influenced by the accuracy of the subtractive CAM procedure. Little is known about how CAM strategies might influence the fit of CAD/CAM fabricated restorations. The aim of this study was to three-dimensionally evaluate the fit of CAD/CAM fabricated zirconia-reinforced lithium silicate ceramic partial crowns fabricated with three different CAM strategies. The null hypothesis was that different CAM strategies did not influence the fitting accuracy of CAD/CAM fabricated zirconia-reinforced lithium silicate ceramic partial crowns. Preparation for a partial crown was performed on a maxillary right first molar on a typodont. A chairside CAD/CAM system with the intraoral scanning device CEREC Omnicam (Dentsply Sirona, York, PA, USA) and the 3+1 axis milling unit CEREC MCXL was used. There were three groups with different CAM strategies: step bur 12 (12), step bur 12S (12S), and two step-mode (12TWO). The zirconia-reinforced lithium silicate ceramic Celtra Duo (Dentsply Sirona) was used as the CAD/CAM material. A new 3D method for evaluating the fit was applied, consisting of the quadrant scan with the intraoral scanning device CEREC Omnicam. The scan of the PVS material adherent to the preparation and the preparation scan were matched, and the difference analysis was performed with special software OraCheck (Cyfex AG, Zurich, Switzerland). Three areas were selected for analysis: margin (MA), axial (AX), and occlusal (OC). Statistical analysis was performed using 80% percentile, one-way ANOVA, and the post hoc Scheffé test with α=0.05. Statistically significant differences were found both within and between the test groups. The aspect axial fit results varied from 90.5 ± 20.1 μm for the two-step milling mode (12TWO_AX) to 122.8 ± 12.2 μm for the milling with step bur 12S (12S_AX). The worst result in all groups was found for the aspect occlusal fit with the highest

Special Section: Complementary and Alternative Medicine (CAM):Quiz on Complementary and Alternative Medicine

Science.gov (United States)

... Special Section CAM Quiz on Complementary and Alternative Medicine Past Issues / Winter 2009 Table of Contents For ... low back pain. True False Complementary and alternative medicine (CAM) includes: Meditation Chiropractic Use of natural products, ...

Tufting enteropathy with EpCAM mutation: case report

Directory of Open Access Journals (Sweden)

Karla Lais Pêgas

2014-06-01

Full Text Available Tufting enteropathy (TE, also known as intestinal epithelial dysplasia (IED, is a rare congenital enteropathy related to an earlyonset of severe intractable diarrhea due to specific abnormalities of the intestinal epithelium and mutations of the EpCAM gene. TE is characterized by clinical and histological heterogeneity, such as with low or without mononuclear cell infiltration of the lamina propria, and abnormalities of basement membrane. TE can be associated with malformations, other epithelial diseases, or to abnormal enterocytes development and/or differentiation. The authors report a case of a Brazilian child with TE associated with c.556-14A>G mutation in the EpCAM gene (NM_002354.2.

Comparative characterization of a novel cad-cam polymer-infiltrated-ceramic-network.

Science.gov (United States)

Albero, Alberto; Pascual, Agustín; Camps, Isabel; Grau-Benitez, María

2015-10-01

The field of dental ceramics for CAD-CAM is enriched with a new innovative material composition having a porous three-dimensional structure of feldspathic ceramic infiltrated with acrylic resins.The aim of this study is to determine the mechanical properties of Polymer-Infiltrated-Ceramic-Network (PICN) and compare its performance with other ceramics and a nano-ceramic resin available for CAD-CAM systems. In this study a total of five different materials for CAD-CAM were investigated. A polymer-infiltrated ceramic (Vita Enamic), a nano-ceramic resin (Lava Ultimate), a feldspathic ceramic (Mark II), a lithium disilicate ceramic (IPS-e max CAD) and finally a Leucite based ceramic (Empress - CAD). From CAD-CAM blocks, 120 bars (30 for each material cited above) were cut to measure the flexural strength with a three-point-bending test. Strain at failure, fracture stress and Weibull modulus was calculated. Vickers hardness of each material was also measured. IPS-EMAX presents mechanical properties significantly better from the other materials studied. Its strain at failure, flexural strength and hardness exhibited significantly higher values in comparison with the others. VITA ENAMIC and LAVA ULTIMATE stand out as the next most resistant materials. The flexural strength, elastic modulus similar to a tooth as well as having less hardness than ceramics make PICN materials an option to consider as a restorative material. Ceramic infiltrated with resin, CAD-CAM, Weibull modulus, flexural strength, micro hardness.

Expression of EpCam and Villin in Barrett’s Esophagus and in Gastric Cardia

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Mario Anders

2008-01-01

Full Text Available In the current study we aimed to clarify the potential of EpCAM and villin as in vivo biomarkers for both Barrett esophagus (BE-associated neoplasia and BE versus cardiac mucosa. Immunohistochemical staining in BE with various degrees of intraepithelial neoplasia (IN, Barrett carcinoma (BC and in normal cardiac mucosa (CM revealed a lack of EpCam and villin in squamous esophageal epithelium. All specimens of IN and BC showed EpCam with varying staining intensities. In 57% of CM samples a weak signal was detected; the remainder displayed strong EpCam expression. Villin was found in 97% of BE specimens and in all those with IN; 37% of BC and 75% of CM specimens were also positive. We conclude that expression of EpCam and villin differs only between squamous epithelium and BE. Determination of these proteins does not allow discrimination between different degrees of neoplasia or between esophageal intestinal metaplasia and cardiac mucosa.

Quantitative determination of the organ distribution of the cell adhesion molecule cell-CAM 105 by radioimmunoassay

International Nuclear Information System (INIS)

Odin, P.; Oebrink, B.

1987-01-01

The authors have previously identified a 105,000-Da plasma membrane glycoprotein, denoted cell-CAM 105, that is involved in intercellular adhesion of reaggregating rat hepatocytes. In this communication they report on the development of a radioimmunoassay for cell-CAM 105, employing purified cell-CAM 105, specific antisera against the molecule, and formalin-fixed protein A-containing staphylococci for precipitation of the immune complexes. The assay was shown to be sensitive, specific, precise, rapid, and easy to perform. They used this radioimmunoassay in investigations of the occurrence of cell-CAM 105 in different rat organs. Cell-CAM 105 was present in a wide spectrum of organs in varying amounts. The highest concentrations were found in the gastrointestinal tract, liver, some secretory glands, vagina, kidney, and lung. The results were confirmed by immunoblotting, which revealed one distinct protein component, corresponding to cell-CAM 105, in each positive organ

The Role of Public Interaction with the Juno Mission: Contextual Information about the Atmosphere and Target Selection for the JunoCam

Science.gov (United States)

Orton, G. S.; Hansen, C. J.; Momary, T.; Bolton, S. J.

2016-12-01

Among the many "firsts" of the Juno mission is the open enlistment of the public in the operation of its visible camera, JunoCam. Although the scientific thrust of the Juno mission is largely focused on innovative approaches to understanding the structure and composition of the interior of Jupiter, JunoCam was added to the payload largely to function in the role of education and public outreach (E/PO). For the first time, the public will be able to engage in the discussion and choice of targets for a major NASA mission, other than two images of Jupiter's polar regions that will be made on each orbit. The discussion about which "electable" features to image is enabled by a continuously updated map of Jupiter's cloud system while Jupiter is far enough from the sun to be observable by the amateur community. This map is created bi-weekly from a set of images uploaded by a world-wide network of amateur astronomers, ranging from very devoted astrophotographers to telescope and video `hobbyists'. Juno therefore engages the world-wide amateur-astronomy community as a vast network of co-investigators, whose products stimulate conversation and global public awareness of Jupiter and Juno's investigative role. Contributed images also provide a temporal context to inform the Juno atmospheric investigation team of the state and evolution of the atmosphere. These bi-weekly maps provide the focus for ongoing discussion about various planetary features over a long time frame. Approximately two weeks before Juno's closest approach to Jupiter on each orbit, starting in mid-November of 2016, the atmospheric features that have been under discussion and will be in the field of view of the instrument nominated for voting, and the public will vote on where to point JunoCam's "elective" features (each orbit will otherwise image the north polar region and south polar region from a non-oblique viewpoint for the first time in over 40 years since the passage of Pioneer 11. The Juno mission

Subaru/COMICS Mid-Infrared Observation of the Near-Nucleus Region of Comet 17P/Holmes at the Early Phase of an Outburst

Science.gov (United States)

Watanabe, Jun-Ichi; Honda, Mitsuhiko; Ishiguro, Masateru; Ootsubo, Takafumi; Sarugaku, Yuki; Kadono, Toshihiko; Sakon, Itsuki; Fuse, Tetsuharu; Takato, Naruhisa; Furusho, Reiko

2009-08-01

Mid-infrared 8--25μm imaging and spectroscopic observations of the comet 17P/Holmes in the early phase of its outburst in brightness were performed on 2007 October 25--28UT using the Cooled Mid-Infrared Camera and Spectrometer (COMICS) on the 8.2-m Subaru Telescope. We detected an isolated dust cloud that moved toward the south-west direction from the nucleus. The 11.2μm peak of a crystalline silicate feature onto a broad amorphous silicate feature was also detected both in the central condensation of the nucleus and an isolated dust cloud. The color temperature of the isolated dust cloud was estimated to be ˜200K, which is slightly higher than the black-body temperature. Our analysis of the motion indicates that the isolated cloud moved anti-sunward. We propose several possibilities for the motion of the cloud: fluffy dust particles in the isolated cloud started to depart from the nucleus due to radiation pressure almost as soon as the main outburst occurred, or dust particles moved by some other anti-sunward forces, such as a rocket effect and photophoresis when the surrounding dust coma became optically thin. The origin and the nature of the isolated dust cloud are discussed in this paper.

CAD/CAM/AM applications in the manufacture of dental appliances.

Science.gov (United States)

Al Mortadi, Noor; Eggbeer, Dominic; Lewis, Jeffrey; Williams, Robert J

2012-11-01

The purposes of this study were to apply the latest developments in additive manufacturing (AM) construction and to evaluate the effectiveness of these computer-aided design and computer-aided manufacturing (CAD/CAM) techniques in the production of dental appliances. In addition, a new method of incorporating wire into a single build was developed. A scanner was used to capture 3-dimensional images of Class II Division 1 dental models that were translated onto a 2-dimensional computer screen. Andresen and sleep-apnea devices were designed in 3 dimensions by using FreeForm software (version 11; Geo Magics SensAble Group, Wilmington, Mass) and a phantom arm. The design was then exported and transferred to an AM machine for building. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

Is Ep-CAM Expression a Diagnostic and Prognostic Biomarker for Colorectal Cancer? A Systematic Meta-Analysis

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Susu Han

2017-06-01

Conclusions: The present findings suggest that Ep-CAM expression may be associated with CRC carcinogenesis, while the loss of Ep-CAM expression is correlated with the progression, metastasis, and poor prognosis of CRC. Ep-CAM expression may be a useful biomarker for the clinical diagnosis of CRC.

Use of Complementary and Alternative Medicine (CAM) in cancer patients: An Italian multicenter survey.

Science.gov (United States)

Berretta, Massimiliano; Della Pepa, Chiara; Tralongo, Paolo; Fulvi, Alberto; Martellotta, Ferdinando; Lleshi, Arben; Nasti, Guglielmo; Fisichella, Rossella; Romano, Carmela; De Divitiis, Chiara; Taibi, Rosaria; Fiorica, Francesco; Di Francia, Raffaele; Di Mari, Anna; Del Pup, Lino; Crispo, Anna; De Paoli, Paolo; Santorelli, Adriano; Quagliariello, Vincenzo; Iaffaioli, Rosario Vincenzo; Tirelli, Umberto; Facchini, Gaetano

2017-04-11

Complementary and Alternative Medicine (CAM) include a wide range of products (herbs, vitamins, minerals, and probiotics) and medical practices, developed outside of the mainstream Western medicine. Patients with cancer are more likely to resort to CAM first or then in their disease history; the potential side effects as well as the costs of such practices are largely underestimated. We conducted a descriptive survey in five Italian hospitals involving 468 patients with different malignancies. The survey consisted of a forty-two question questionnaire, patients were eligible if they were Italian-speaking and receiving an anticancer treatment at the time of the survey or had received an anticancer treatment no more than three years before participating in the survey. Of our patients, 48.9% said they use or have recently used CAM. The univariate analysis showed that female gender, high education, receiving treatment in a highly specialized institute and receiving chemotherapy are associated with CAM use; at the multivariate analysis high education (Odds Ratio, (OR): 1.96 95% Confidence Interval, CI, 1.27-3.05) and receiving treatment in a specialized cancer center (OR: 2.75 95% CI, 1.53-4.94) were confirmed as risk factors for CAM use. Roughly half of our patients receiving treatment for cancer use CAM. It is necessary that health professional explore the use of CAM with their cancer patients, educate them about potentially beneficial therapies in light of the limited available evidence of effectiveness, and work towards an integrated model of health-care provision.

Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer

NARCIS (Netherlands)

van der Gun, B. T. F.; de Groote, M. L.; Kazemier, H. G.; Arendzen, A. J.; Terpstra, P.; Ruiters, M. H. J.; McLaughlin, P. M. J.; Rots, M. G.

2011-01-01

BACKGROUND: The epithelial cell adhesion molecule (EpCAM) is overexpressed on carcinomas, and its downregulation inhibits the oncogenic potential of multiple tumour types. Here, we investigated underlying mechanisms of epcam overexpression in ovarian carcinoma. METHODS: Expression of EpCAM and DNA

Illness narratives in cancer: CAM and spiritual practices

DEFF Research Database (Denmark)

Ulrich, Anita; Evron, Lotte; Ostenfeld-Rosenthal, Ann

2011-01-01

Objectives: In this paper,we investigate Danish cancer patients’ narratives on spiritual beliefs and practices and the relationship these practices may have to complementary and alternative medicine (CAM). Design: Narrative inquiry is used to uncover how spiritual beliefs and practices may......, religious and spiritual issues were not extensively unfolded in participants’ illness narratives. However, these issues were significantly elaborated on in narratives by four female participants. Conclusion: We propose that for some cancer patients CAM may function, not only or primarily as a treatment...... for cancer related symptoms and side effects, but as a spiritual practice as well. For some individuals this may be true to an even higher extent than in established religious institutions....

Sources of CAM3 vorticity bias during northern winter from diagnostic study of the vorticity equation

Energy Technology Data Exchange (ETDEWEB)

Grotjahn, Richard [University of California, Department of Land, Air and Water Resources, Davis, CA (United States); Pan, Lin-Lin; Tribbia, Joseph [National Center for Atmospheric Research, Boulder, CO (United States)

2011-06-15

CAM3 (Community Atmosphere Model version 3) simulation bias is diagnosed using the vorticity equation. The study compares CAM3 output with ECMWF (European Centre for Medium-Range Weather Forecasts) 40 year reanalysis (ERA-40) data. A time mean vorticity bias equation is also formulated and the terms are grouped into categories: linear terms, nonlinear terms, transient contributions, and friction (calculated as a residual). Frontal cyclone storms have much weaker band passed kinetic energy and enstrophy in CAM3. The downstream end of the North Atlantic storm track (NAST) has large location error. While the vorticity equation terms have similar amplitude ranking in CAM3 and ERA-40 at upper levels, the ranking differs notably in the lower troposphere. The linear and friction terms dominate the vorticity bias equation. The transient terms contribute along the storm track, but the nonlinear terms are generally much smaller, with the primary exception being over the Iberian peninsula. Friction is much stronger in CAM3. As evidence, nearly all wavelengths (including the longest planetary waves) have smaller amplitude in CAM3 than in ERA-40 vorticity data. Negative near surface vorticity tendency bias on the European side of the Arctic is linked to the NAST track error (evident in the divergence term). CAM3 misses the Beaufort high in sea level pressure (SLP) due to low level warm temperature bias, too little vortex compression, and to too little horizontal advection of negative vorticity compared with ERA-40. Generally lower SLP values in CAM3 over the entire Arctic follow from lower level warm bias in CAM3. (orig.)

Screening for retinopathy of prematurity-a comparison between binocular indirect ophthalmoscopy and RetCam 120

Directory of Open Access Journals (Sweden)

Shah Parag

2006-01-01

Full Text Available Aim: To compare the photographic screening for retinopathy of prematurity (ROP using RetCam 120 with binocular indirect ophthalmoscope (BIO, which is the current gold standard. Setting and Design: Prospective, comparative study. Materials and Methods: A total of 87 RetCam examinations were performed on 27 premature babies. They were stored in a separate file after deleting the identifying information. At the same visit using the BIO with scleral depression, an experienced vitreoretinal surgeon evaluated the fundus in detail. A masked examiner then evaluated the RetCam photographs for presence or absence of ROP, the stage and zone of the disease, and the presence or absence of plus disease. These data were then compared with the BIO findings to determine the sensitivity, specificity, and the positive and negative predictive values of the method. Results: ROP was detected in 63 of 87 examinations by BIO and in 56 of 87 RetCam examinations. Nine RetCam examinations were false-negative and two were false-positive. Sensitivity of RetCam was 85.71% (54/63 and specificity was 91.66% (22/24. The positive and negative predictive values were 96.43% and 70.97% respectively. Conclusion: Nine cases having ROP were missed by the RetCam. All these cases were either in zone 3 or the outer part of zone 2, which later regressed. These were missed mostly because of the restricted mobility of the camera head caused by its size and the barrier caused by the lid speculum arms. No case of threshold ROP was missed. RetCam may replace BIO for screening of ROP.

Estudo anatômico do terço proximal do fêmur: impacto femoroacetabular e o efeito cam Anatomic study of the proximal third of the femur: femoroacetabular impact and the cam effect

Directory of Open Access Journals (Sweden)

Pedro José Labronici

2009-04-01

Full Text Available OBJETIVO: Analisar as varia��ões anatômicas da extremidade proximal do fêmur que pudessem desenvolver o impacto femoroacetabular. MÉTODOS: Foram utilizados 199 espécimes anatômicos de fêmures esqueleticamente maduros. Os fêmures foram medidos para determinar o ângulo da anteversão do colo femoral, ângulo cervicodiafisário, esfericidade da cabeça femoral em ântero-posterior e súpero-inferior, ângulo entre a epífise e o colo femoral anterior, ângulo entre a epífise e o colo em perfil, distância em ântero-posterior a 5mm da junção cabeça e colo e distância em ântero-posterior da base do colo. RESULTADOS: Observou-se que o subgrupo com impacto apresentou diâmetro da junção a 5mm (p = 0,0001 e cam-cabeça (% (p = 0,0001 significativamente maiores e base-cam (% (p = 0,0001 significativamente menor que o subgrupo sem impacto. Identificou-se que cam-cabeça (% > 80 e base-cam (% OBJECTIVE: to analyze anatomical variations of the proximal end of femur that could cause a femoroacetabular impact. METHODS: 199 skeletically mature anatomical specimens of femurs were used. The femurs were measured in order to determine the anteversion angle of the femoral neck, neckshaft angle, sphericity of the femoral head at anteroposterior and superoinferior, angle between epiphysis and the anterior femoral neck, angle between epiphysis and the neck at lateral plane, anteroposterior distance at 5mm of the head and neck junction and anteroposterior distance of the neck base. RESULTS: we found that the impact subgroup presented a significantly larger junction diameter of 5mm (p = 0.0001 and cam-head (% (p= 0.0001, while base-cam (% (p = 0.0001 showed a significantly smaller diameter than the subgroup without impact. It was identified that cam-head (% > 80 e base-cam (% < 73 were identified as the optimal impact points. CONCLUSION: our study showed that the effect cam, caused by anatomical variations of the proximal femoral end focused the

A Space Cam Mechanism for Power Transmission of an Opposite-cylinder Piston Engine

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Zhang Haoyue

2015-01-01

Full Text Available For the purpose of improving the engine’s power density, we put forward a new type of power transmission mechanism which is used for opposed-cylinder engine. The gas pressure acts on the cam through the piston and push rod, and the spindle rotation of external is driven by the cam. The design of spatial cam work surface is completed by using the enveloping theory of a family of space curves, the force between roller and cam is analyzed using dynamic analysis software. Under the condition of equal number, size and stroke of piston, the new one with larger power density is more compact in structure than the traditional power transmission mechanism, and the reaction force on either side of the main shaft and the acting force between pistons and cylinders are smaller than those in traditional one, which prolongs the service life of the pistons.

Application of CAD/CAE/CAM in forging process: a review

International Nuclear Information System (INIS)

Ahmad Baharuddin Abdullah; Hamouda, A.M.S.

2005-01-01

Forging can be described as the process in which metal is plastically deformed with application of huge pressure. The process not only changes the shape but also improves the properties of the forged parts due to grain size refinement. Conventionally, the empirical trial and error method has been applied, but recently there are various tools are employed to improved product quality and economic of the process. For example, Computer Aided Design (CAD) is widely used in modeling of the process, while Computer Aided Engineering (CAE) tools have been utilized in analyzing the process. To physically demonstrate the process, Computer Aided Manufacturing (CAM) such as CNC machine has been exploited. In order to improve forging process efficiency, an integrated system that combines all advantages of CAD, CAM and CAE need to be developed. This paper presents an overview of computer aided simulation such as CAD, CAE and CAM application in forging process. (Author)

Gamma–neutron imaging system utilizing pulse shape discrimination with CLYC

International Nuclear Information System (INIS)

Whitney, Chad M.; Soundara-Pandian, Lakshmi; Johnson, Erik B.; Vogel, Sam; Vinci, Bob; Squillante, Michael; Glodo, Jarek; Christian, James F.

2015-01-01

Recently, RMD has investigated the use of CLYC (Cs 2 LiYCl 6 :Ce), a new and emerging scintillation material, in a gamma–neutron coded aperture imaging system based on RMD's commercial RadCam TM instrument. CLYC offers efficient thermal neutron detection, fast neutron detection capabilities, excellent pulse shape discrimination (PSD), and gamma-ray energy resolution as good as 4% at 662 keV. PSD improves the isolation of higher energy gammas from thermal neutron interactions (>3 MeV electron equivalent peak), compared to conventional pulse height techniques. The scintillation emission time in CLYC provides the basis for PSD; where neutron interactions result in a slower emission rise and decay components while gamma interactions result in a faster emission components. By creating a population plot based on the ratio of the decay tail compared to the total integral amplitude (PSD ratio), discrimination of gammas, thermal neutrons, and fast neutrons is possible. Previously, we characterized the CLYC-based RadCam system for imaging gammas and neutrons using a layered W-Cd coded aperture mask and employing only pulse height discrimination. In this paper, we present the latest results which investigate gamma-neutron imaging capabilities using PSD. An FPGA system is used to acquire the CLYC–PSPMT last dynode signals, determine a PSD ratio for each event, and compare it to a calibrated PSD cutoff. Each event is assigned either a gamma (low) or neutron (high) flag signal which is then correlated with the imaging information for each event. - Highlights: • The latest results are presented for our CLYC RadCam-2 system which investigate gamma–neutron imaging using pulse shape discrimination. • CLYC RadCam-2 system successfully discriminates gammas, thermal neutrons, and fast neutrons by employing a fully integrated, FPGA-based PSD system. • Imaging of our 252 Cf source was possible using both pulse height and pulse shape discrimination with CLYC. • Imaging

The use of complementary alternative medicine (CAM) in 1 001 German adults: results of a population-based telephone survey.

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Bücker, B; Groenewold, M; Schoefer, Y; Schäfer, T

2008-01-01

The objective of this study was to evaluate the patterns of use of complementary alternative medicine (CAM) in a representative adult population in Germany. A population-based telephone survey was conducted in Lübeck, Germany. We performed computer-assisted telephone interviews (CATI) in order to obtain information on demographics, health status, prevalence of CAM usage, motivation for using CAM, type of CAM and health problems for which CAM were used. 1,001 adults (median age 48 years) participated in the study (response 46.8%). 79.6% of the interviewed subjects reported health problems. The most frequently named problems were chronic pain (45.3%), circulation problems (32.9%) and colds with fever (27.8%). Non-users of CAM had a lower incidence (76.6%) of overall illness than users (83.5%) (OR 0.65, 0.47-0.89). 42.3% of the participants had used CAM. The CAM user group consisted of significantly more females (72.8 vs. 55.5%) (OR 2.32, 1.74-3.08) and involved better educated subjects (school education >12 years, 36.6 vs. 27.9%, OR 3.25, 1.35-7.81) than the non-user group. The main health problems for which CAM was used were chronic pain (36.3%), some cases of uncomplicated colds (16.9%) and for improving general health (14.7%). Three procedures accounted for the majority of usage: Acupuncture (34.5%), homeopathy (27.3%) and herbal medicine (9.7%). A large number of participants reported as the main reason for using CAM the wish to avoid drugs as much as possible (31.7%). 26.7% reported opting for CAM due to the recommendation of their physician. 23.9% gave unsatisfactory results of conventional medicine as reason for CAM usage. CAM is used widely for different complaints by the general population. This frequent use of CAM has implications for the health-care system and health policy.

Optional use of CAM photosynthesis in two C4 species, Portulaca cyclophylla and Portulaca digyna.

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Holtum, Joseph A M; Hancock, Lillian P; Edwards, Erika J; Winter, Klaus

2017-07-01

Low levels of crassulacean acid metabolism (CAM) are demonstrated in two species with C 4 photosynthesis, Portulaca cyclophylla and P. digyna. The expression of CAM in P. cyclophylla and P. digyna is facultative, i.e. optional. Well-watered plants did not accumulate acid at night and exhibited gas-exchange patterns consistent with C 4 photosynthesis. CAM-type nocturnal acidification was reversible in that it was induced following drought and lost when droughted plants were rewatered. In P. cyclophylla, droughting was accompanied by a small but discernible net uptake of CO 2 during the dark, whereas in P. digyna, net CO 2 exchange at night approached the CO 2 compensation point but did not transition beyond it. This report brings the number of known C 4 species with a capacity for expressing CAM to six. All are species of Portulaca. The observation of CAM in P. cyclophylla and P. digyna is the first for species in the opposite-leaved (OL) Portulacelloid-anatomy lineage of Portulaca and for the Australian clade therein. The other four species are within the alternate-leaved (AL) lineage, in the Atriploid-anatomy Oleracea and the Pilosoid-anatomy Pilosa clades. Studies of the evolutionary origins of C 4 and CAM in Portulaca will benefit from a more wide-range survey of CAM across its species, particularly in the C 3 -C 4 intermediate-containing Cryptopetala clade. Copyright © 2017 Elsevier GmbH. All rights reserved.

The influence of polishing techniques on pre-polymerized CAD\\CAM acrylic resin denture bases.

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Alammari, Manal Rahma

2017-10-01

Lately, computer-aided design and computer-aided manufacturing (CAD/CAM) has broadly been successfully employed in dentistry. The CAD/CAM systems have recently become commercially available for fabrication of complete dentures, and are considered as an alternative technique to conventionally processed acrylic resin bases. However, they have not yet been fully investigated. The purpose of this study was to inspect the effects of mechanical polishing and chemical polishing on the surface roughness (Ra) and contact angle (wettability) of heat-cured, auto-cured and CAD/CAM denture base acrylic resins. This study was conducted at the Advanced Dental Research Laboratory Center of King Abdulaziz University from March to June 2017. Three denture base materials were selected: heat cure poly-methylmethacrylate resin, thermoplastic (polyamide resin) and (CAD\\CAM) denture base resin. Sixty specimens were prepared and divided into three groups, twenty in each. Each group was divided according to the polishing techniques into (Mech P) and (Chem P), ten specimens in each; surface roughness and wettability were investigated. Data were analyzed by SPSS version 22, using one-way ANOVA and Pearson coefficient. One-way analysis of variance (ANOVA) and post hoc tests were used for comparing the surface roughness values between three groups which revealed a statistical significant difference between them (p 1 CAD\\CAM denture base material (group III) showed the least mean values (1.08±0.23, 1.39±0.31, Mech P and Chem P respectively). CAD/CAM showed the least contact angle in both polishing methods, which were statistically significant at 5% level (p=0.034 and pCAD\\CAM denture base resin with superior smooth surface compared to chemical polishing. Mechanical polishing is considered the best effective polishing technique. CAD/CAM denture base material should be considered as the material of choice for complete denture construction in the near future, especially for older dental

Complementary and alternative medicine (CAM) practices and dietary patterns in children with inflammatory bowel disease in Singapore and Malaysia.

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Ong, Fangyi; Seah Lee, Way; Lin, Charlotte; Ng, Ruey Terng; Yee Wong, Shin; Lim, Su Lin; Quak, Seng Hock; Aw, Marion

2017-12-26

The use of complementary and alternative medicine (CAM) has been associated with adverse effects and self-imposed dietary restrictions. The prevalence of its use in Asian children with inflammatory bowel disease (IBD) is unknown. We aimed to determine the prevalence, types, and factors associated with the use of CAM among children with IBD from Singapore and Malaysia, and to ascertain if dietary restriction was prevalent in patients who used CAM. A cross-sectional study was conducted in which parents of children with IBD attending two tertiary pediatric IBD referral centres in Singapore and Malaysia were interviewed. Data about demographics, conventional treatment, complementary therapies and dietary patterns were collected in a questionnaire. Of 64 children with IBD interviewed, 83% (n = 53) reported the use of CAM (Singapore [90%] vs. Malaysia [76%]; p = 0.152). The median number of CAM agents used was two (range 1-10). The three most common types of CAM used were probiotics (64%), vitamin and mineral supplements (55%), and food-based therapies (36%). Among individual CAM categories, the use of food-based therapies was correlated significantly with nationality (r = 0.497, p history of weight loss due to IBD (r = 0.340, p = 0.013) and avoidance of certain foods to prevent a relapse (r = 0.289, p = 0.036). Parents who rated their child's disease activity as more severe were less likely to use CAM (r = -0.257, p = 0.041). Fifty-nine percent of CAM users reported physician awareness of their CAM use. The overall self-perceived efficacy of CAM in improving IBD symptoms was 34%. Of the dietary patterns explored, only intake of dairy products was associated with CAM use (r = 0.306, p = 0.019). Use of CAM is prevalent in children with IBD in Malaysia and Singapore. Further studies to elucidate reasons influencing CAM use, dietary patterns and efficacy of commonly used CAM would be required. Copyright © 2018. Published by Elsevier B.V.

Complementary and alternative medicine (CAM) use in an Italian cohort of pediatric headache patients: the tip of the iceberg.

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Dalla Libera, D; Colombo, B; Pavan, G; Comi, G

2014-05-01

The use of complementary alternative medicine (CAM) in paediatric populations is considerably increased, especially for pain and chronic conditions, as demonstrated by epidemiological surveys both in Europe and in the USA. In our study, CAM was used in 76 % patients of a cohort of 124 children affected by headache (age 4-16 years; 67 % female; 70 % migraine without aura, 12 % migraine with aura, 18 % tensive headache according to IHS criteria) consecutively recruited at a Pediatric Headache University Center. CAM was used as preventive treatment in 80 % cases. The main reasons for seeking CAM were: the wish of avoiding chronic use of drugs with their related side effects, the desire of an integrated approach, the reported inefficacy of conventional medicine, and a more suitable children disposition to CAM than to pharmacological compound. Female gender, younger age, migraine without aura, parents' higher educational status, maternal use of CAM and other associated chronic conditions, correlated with CAM use (p CAM also to treat other diseases (i.e. allergies, colitis, asthma, insomnia, muscle-scheletric disorders and dysmenorrhoea). The most assumed CAM were: herbal remedies (64 %) such as Valeriana, Ginkgo biloba, Boswellia serrata, Vitex agnus-castus, passion flower, Linden tree; vitamins/minerals supplements (40 %) with magnesium, 5-Hydroxytryptophan, vitamin B6 or B12, Multivitamin compounds; Homeopathy (47 %) with Silicea, Ignatia Amara, Pulsatilla, Aconitum, Nux Vomica, Calcarea phosphorica; physical treatment (45 %) such as Ayurvedic massage, shiatsu, osteopathy; yoga (33 %); acupuncture (11 %). CAM-often integrated with conventional care-was auto-prescribed in 30 % of the cases, suggested by non-physician in 22 %, by the General Practitioner in 24 % and by paediatrician in 24 %. Both general practitioners and neurologists were mostly unaware of their patients' CAM use. In conclusion, neurologists should inquire for CAM use and be prepared to learn about CAM

Understanding, perceptions and self-use of complementary and alternative medicine (CAM) among Malaysian pharmacy students.

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Hasan, Syed S; Yong, Chew S; Babar, Muneer G; Naing, Cho M; Hameed, Abdul; Baig, Mirza R; Iqbal, Shahid M; Kairuz, Therese

2011-10-13

In recent times the basic understanding, perceptions and CAM use among undergraduate health sciences students have become a topic of interest. This study was aimed to investigate the understanding, perceptions and self-use of CAM among pharmacy students in Malaysia. This cross-sectional study was conducted on 500 systematically sampled pharmacy students from two private and one public university. A validated, self-administered questionnaire comprised of seven sections was used to gather the data. A systematic sampling was applied to recruit the students. Both descriptive and inferential statistics were applied using SPSS® version 18. Overall, the students tend to disagree that complementary therapies (CM) are a threat to public health (mean score = 3.6) and agreed that CMs include ideas and methods from which conventional medicine could benefit (mean score = 4.7). More than half (57.8%) of the participants were currently using CAM while 77.6% had used it previously. Among the current CAM modalities used by the students, CM (21.9%) was found to be the most frequently used CAM followed by Traditional Chinese Medicine (TCM) (21%). Most of the students (74.8%) believed that lack of scientific evidence is one of the most important barriers obstructing them to use CAM. More than half of the students perceived TCM (62.8%) and music therapy (53.8%) to be effective. Majority of them (69.3%) asserted that CAM knowledge is necessary to be a well-rounded professional. This study reveals a high-percentage of pharmacy students who were using or had previously used at least one type of CAM. Students of higher professional years tend to agree that CMs include ideas and methods from which conventional medicine could benefit.

Understanding, perceptions and self-use of complementary and alternative medicine (CAM among Malaysian pharmacy students

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Baig Mirza R

2011-10-01

Full Text Available Abstract Background In recent times the basic understanding, perceptions and CAM use among undergraduate health sciences students have become a topic of interest. This study was aimed to investigate the understanding, perceptions and self-use of CAM among pharmacy students in Malaysia. Methods This cross-sectional study was conducted on 500 systematically sampled pharmacy students from two private and one public university. A validated, self-administered questionnaire comprised of seven sections was used to gather the data. A systematic sampling was applied to recruit the students. Both descriptive and inferential statistics were applied using SPSS® version 18. Results Overall, the students tend to disagree that complementary therapies (CM are a threat to public health (mean score = 3.6 and agreed that CMs include ideas and methods from which conventional medicine could benefit (mean score = 4.7. More than half (57.8% of the participants were currently using CAM while 77.6% had used it previously. Among the current CAM modalities used by the students, CM (21.9% was found to be the most frequently used CAM followed by Traditional Chinese Medicine (TCM (21%. Most of the students (74.8% believed that lack of scientific evidence is one of the most important barriers obstructing them to use CAM. More than half of the students perceived TCM (62.8% and music therapy (53.8% to be effective. Majority of them (69.3% asserted that CAM knowledge is necessary to be a well-rounded professional. Conclusions This study reveals a high-percentage of pharmacy students who were using or had previously used at least one type of CAM. Students of higher professional years tend to agree that CMs include ideas and methods from which conventional medicine could benefit.

Use of selected complementary and alternative medicine (CAM treatments in veterans with cancer or chronic pain: a cross-sectional survey

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Liebschutz Jane M

2006-10-01

Full Text Available Abstract Background Complementary and alternative medicine (CAM is emerging as an important form of care in the United States. We sought to measure the prevalence of selected CAM use among veterans attending oncology and chronic pain clinics and to describe the characteristics of CAM use in this population. Methods The self-administered, mail-in survey included questions on demographics, health beliefs, medical problems and 6 common CAM treatments (herbs, dietary supplements, chiropractic care, massage therapy, acupuncture and homeopathy use. We used the chi-square test to examine bivariate associations between our predictor variables and CAM use. Results Seventy-two patients (27.3% reported CAM use within the past 12 months. CAM use was associated with more education (p = 0.02, higher income (p = 0.006, non-VA insurance (p = 0.003, additional care outside the VA (p = 0.01 and the belief that lifestyle contributes to illness (p = 0.015. The diagnosis of chronic pain versus cancer was not associated with differential CAM use (p = 0.15. Seventy-six percent of CAM non-users reported that they would use it if offered at the VA. Conclusion Use of 6 common CAM treatments among these veterans is lower than among the general population, but still substantial. A large majority of veterans reported interest in using CAM modalities if they were offered at the VA. A national assessment of veteran interest in CAM may assist VA leaders to respond to patients' needs.

Use of selected complementary and alternative medicine (CAM) treatments in veterans with cancer or chronic pain: a cross-sectional survey.

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McEachrane-Gross, F Patricia; Liebschutz, Jane M; Berlowitz, Dan

2006-10-06

Complementary and alternative medicine (CAM) is emerging as an important form of care in the United States. We sought to measure the prevalence of selected CAM use among veterans attending oncology and chronic pain clinics and to describe the characteristics of CAM use in this population. The self-administered, mail-in survey included questions on demographics, health beliefs, medical problems and 6 common CAM treatments (herbs, dietary supplements, chiropractic care, massage therapy, acupuncture and homeopathy) use. We used the chi-square test to examine bivariate associations between our predictor variables and CAM use. Seventy-two patients (27.3%) reported CAM use within the past 12 months. CAM use was associated with more education (p = 0.02), higher income (p = 0.006), non-VA insurance (p = 0.003), additional care outside the VA (p = 0.01) and the belief that lifestyle contributes to illness (p = 0.015). The diagnosis of chronic pain versus cancer was not associated with differential CAM use (p = 0.15). Seventy-six percent of CAM non-users reported that they would use it if offered at the VA. Use of 6 common CAM treatments among these veterans is lower than among the general population, but still substantial. A large majority of veterans reported interest in using CAM modalities if they were offered at the VA. A national assessment of veteran interest in CAM may assist VA leaders to respond to patients' needs.

3D virtual planning in orthognathic surgery and CAD/CAM surgical splints generation in one patient with craniofacial microsomia: a case report

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Vale, Francisco; Scherzberg, Jessica; Cavaleiro, João; Sanz, David; Caramelo, Francisco; Maló, Luísa; Marcelino, João Pedro

2016-01-01

Objective: In this case report, the feasibility and precision of tridimensional (3D) virtual planning in one patient with craniofacial microsomia is tested using Nemoceph 3D-OS software (Software Nemotec SL, Madrid, Spain) to predict postoperative outcomes on hard tissue and produce CAD/CAM (Computer Aided Design/Computer Aided Manufacturing) surgical splints. Methods: The clinical protocol consists of 3D data acquisition of the craniofacial complex by cone-beam computed tomography (CBCT) and surface scanning of the plaster dental casts. The ''virtual patient'' created underwent virtual surgery and a simulation of postoperative results on hard tissues. Surgical splints were manufactured using CAD/CAM technology in order to transfer the virtual surgical plan to the operating room. Intraoperatively, both CAD/CAM and conventional surgical splints are comparable. A second set of 3D images was obtained after surgery to acquire linear measurements and compare them with measurements obtained when predicting postoperative results virtually. Results: It was found a high similarity between both types of surgical splints with equal fitting on the dental arches. The linear measurements presented some discrepancies between the actual surgical outcomes and the predicted results from the 3D virtual simulation, but caution must be taken in the analysis of these results due to several variables. Conclusions: The reported case confirms the clinical feasibility of the described computer-assisted orthognathic surgical protocol. Further progress in the development of technologies for 3D image acquisition and improvements on software programs to simulate postoperative changes on soft tissue are required. PMID:27007767

Radiographic Prevalence of Dysplasia, Cam, and Pincer Deformities in Elite Ballet.

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Harris, Joshua D; Gerrie, Brayden J; Varner, Kevin E; Lintner, David M; McCulloch, Patrick C

2016-01-01

The demands of hip strength and motion in ballet are high. Hip disorders, such as cam and pincer deformities or dysplasia, may affect dance performance. However, the prevalence of these radiographic findings is unknown. To determine the prevalence of radiographic cam and pincer deformities, borderline dysplasia, and dysplasia in a professional ballet company. Cross-sectional study; Level of evidence, 3. An institutional review board-approved cross-sectional investigation of a professional ballet company was undertaken. Male and female adult dancers were eligible for inclusion. Four plain radiographs were obtained (standing anteroposterior pelvis, bilateral false profile, and supine Dunn 45°) and verified for adequacy. Cam and pincer deformities, dysplasia, borderline dysplasia, and osteoarthritis were defined. All plain radiographic parameters were measured and analyzed on available radiographs. Student t test, chi-square test (and Fisher exact test), and Spearman correlation analyses were performed to compare sexes, groups, and the effect of select radiographic criteria. A total of 47 dancers were analyzed (21 males, 26 females; mean age (±SD), 23.8 ± 5.4 years). Cam deformity was identified in 25.5% (24/94) of hips and 31.9% (15/47) of subjects, with a significantly greater prevalence in male dancers than females (48% hips and 57% subjects vs 8% hips and 12% subjects; P ballet company, a high prevalence of radiographic abnormalities was found, including cam and pincer deformity and dysplasia. The results also revealed several sex-related differences of these abnormalities in this unique population. The long-term implications of these findings in this group of elite athletes remain unknown, and this issue warrants future investigation. © 2015 The Author(s).

Ep-CAM expression in squamous cell carcinoma of the esophagus: a potential therapeutic target and prognostic marker

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Peiper Matthias

2006-06-01

Full Text Available Abstract Background To evaluate the expression and test the clinical significance of the epithelial cellular adhesion molecule (Ep-CAM in esophageal squamous cell carcinoma (SCC to check the suitability of esophageal SCC patients for Ep-CAM directed targeted therapies. Methods The Ep-CAM expression was immunohistochemically investigated in 70 primary esophageal SCCs using the monoclonal antibody Ber-EP4. For the interpretation of the staining results, we used a standardized scoring system ranging from 0 to 3+. The survival analysis was calculated from 53 patients without distant metastasis, with R0 resection and at least 2 months of clinical follow-up. Results Ep-CAM neo-expression was observed in 79% of the tumors with three expression levels, 1+ (26%, 2+ (11% and 3+ (41%. Heterogeneous expression was observed at all expression levels. Interestingly, tumors with 3+ Ep-CAM expression conferred a significantly decreased median relapse-free survival period (log rank, p = 0.0001 and median overall survival (log rank, p = 0.0003. Multivariate survival analysis disclosed Ep-CAM 3+ expression as independent prognostic factor. Conclusion Our results suggest Ep-CAM as an attractive molecule for targeted therapy in esophageal SCC. Considering the discontenting results of the current adjuvant concepts for esophageal SCC patients, Ep-CAM might provide a promising target for an adjuvant immunotherapeutic intervention.

A Review of CAM for Procedural Pain in Infancy: Part II. Other Interventions

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Jennie C. I. Tsao

2008-01-01

Full Text Available This article is the second in a two-part series reviewing the empirical evidence for complementary and alternative medicine (CAM approaches for the management of pain related to medical procedures in infants up to 6 weeks of age. Part I of this series investigated the effects of sucrose with or without non-nutritive sucking (NNS. The present article examines other CAM interventions for procedural pain including music-based interventions, olfactory stimulation, kangaroo care and swaddling. Computerized databases were searched for relevant studies including prior reviews and primary trials. Preliminary support was revealed for the analgesic effects of the CAM modalities reviewed. However, the overall quality of the evidence for these approaches remains relatively weak. Additional well-designed trials incorporating rigorous methodology are required. Such investigations will assist in the development of evidence-based guidelines on the use of CAM interventions either alone or in concert with conventional approaches to provide safe, reliable analgesia for infant procedural pain.

The prevalence, patterns of usage and people's attitude towards complementary and alternative medicine (CAM among the Indian community in Chatsworth, South Africa

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Raidoo Deshandra M

2004-02-01

Full Text Available Abstract Background The purpose of this study was to determine, among the Indian community of Chatsworth, South Africa, the prevalence and utilisation patterns of complementary and alternative medicine (CAM, attitudes associated with CAM use and communication patterns of CAM users with their primary care doctors. Methods Face-to-face structured interviews were conducted in Chatsworth, a suburb of Durban in which South Africans of Indian origin predominantly reside. Participants were 200 randomly selected adult English-speaking Indian residents. Results The prevalence of CAM usage for period 2000/2001 was 38.5% (95% confidence interval 31.7% to 45.6%. Spiritual healing and herbal/natural medicines, including vitamins were the most common types of CAM used, accounting for 42.8% and 48.1% respectively of overall CAM usage. People used CAM to treat conditions including diabetes mellitus, headaches, arthritis and joint pains, stress, skin disorders, backaches, hypertension and nasal disorders. Half of the CAM users used allopathic medicines concurrently. The cost of CAM utilization over this 1-year period, incurred by 80.5% of users for the duration of therapy for their most troublesome condition was below R500 (approximately US$50. Age, sex, marital status, religion, level of education and income were shown not to influence the use of CAM. Greater than half (51.9% of CAM users did so either upon the advice of someone they knew, or after noticing a CAM advertisement in the local press. Seventy-nine percent of CAM users indicated that they had positive outcomes with their treatments. Fifty four percent of CAM users (excluding those using spiritual healing only failed to inform their doctors that they used CAM. The main reason given by half of this group was that informing their doctors did not seem necessary. Conclusion The prevalence of CAM in Chatsworth is similar to findings in other parts of the world. Although CAM was used to treat many different

Two-body wear rate of CAD/CAM resin blocks and their enamel antagonists.

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Stawarczyk, Bogna; Özcan, Mutlu; Trottmann, Albert; Schmutz, Felix; Roos, Malgorzata; Hämmerle, Christoph

2013-05-01

Computer-aided design and computer-aided manufacturing (CAD/CAM) resins exhibit good mechanical properties and can be used as long-term restorations. The wear rate of such resins and their enamel antagonists is unknown. The purpose of this study was to test and compare the 2-body wear rate of CAD/CAM resin blocks. Wear specimens (N=42, n=6) were made from 5 CAD/CAM resins: ZENO PMMA (ZP), artBloc Temp (AT), Telio CAD (TC), Blanc High-class (HC), CAD-Temp (CT); 1 manually polymerized resin: Integral esthetic press (negative control group, IEP); and 1 glass-ceramic: VITA Mark II (positive control group, VM2). The specimens for the wear resistance were aged in a thermomechanical loading machine (49 N, 1.67 Hz, 5/50°C) with human enamel antagonists. The material loss of all specimens before, during, and after aging was evaluated with a 3DS profilometer. The measured material loss data of all tested groups were statistically evaluated with linear mixed model analysis (a=.05). Manually polymerized resin showed significantly higher material wear (P<.001) than all other tested groups. Glass-ceramic showed significantly lower wear values (P<.001) than CAD/CAM resins ZP, AT, HC, CT, and IES. CAD/CAM resin TC was not significantly different from the positive control group. Glass-ceramic showed the highest enamel wear values (P<.001) of all tested resins. No differences were found in the enamel wear among all resins. The glass-ceramic group showed damage in the form of cracks on the worn enamel surface in 50% of specimens. CAD/CAM resins showed lower wear rates than those conventionally polymerized. Only one CAD/CAM resin, TC, presented material wear values comparable with glass-ceramic. The tested glass-ceramic developed cracks in the enamel antagonist and showed the highest enamel wear values of all other tested groups. Copyright © 2013 The Editorial Council of the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

From Artisanal to CAD-CAM Blocks: State of the Art of Indirect Composites.

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Mainjot, A K; Dupont, N M; Oudkerk, J C; Dewael, T Y; Sadoun, M J

2016-05-01

Indirect composites have been undergoing an impressive evolution over the last few years. Specifically, recent developments in computer-aided design-computer-aided manufacturing (CAD-CAM) blocks have been associated with new polymerization modes, innovative microstructures, and different compositions. All these recent breakthroughs have introduced important gaps among the properties of the different materials. This critical state-of-the-art review analyzes the strengths and weaknesses of the different varieties of CAD-CAM composite materials, especially as compared with direct and artisanal indirect composites. Indeed, new polymerization modes used for CAD-CAM blocks-especially high temperature (HT) and, most of all, high temperature-high pressure (HT-HP)-are shown to significantly increase the degree of conversion in comparison with light-cured composites. Industrial processes also allow for the augmentation of the filler content and for the realization of more homogeneous structures with fewer flaws. In addition, due to their increased degree of conversion and their different monomer composition, some CAD-CAM blocks are more advantageous in terms of toxicity and monomer release. Finally, materials with a polymer-infiltrated ceramic network (PICN) microstructure exhibit higher flexural strength and a more favorable elasticity modulus than materials with a dispersed filler microstructure. Consequently, some high-performance composite CAD-CAM blocks-particularly experimental PICNs-can now rival glass-ceramics, such as lithium-disilicate glass-ceramics, for use as bonded partial restorations and crowns on natural teeth and implants. Being able to be manufactured in very low thicknesses, they offer the possibility of developing innovative minimally invasive treatment strategies, such as "no prep" treatment of worn dentition. Current issues are related to the study of bonding and wear properties of the different varieties of CAD-CAM composites. There is also a crucial

GTC/CanariCam Mid-IR Imaging of the Fullerene-rich Planetary Nebula IC 418: Searching for the Spatial Distribution of Fullerene-like Molecules

Science.gov (United States)

Díaz-Luis, J. J.; García-Hernández, D. A.; Manchado, A.; García-Lario, P.; Villaver, E.; García-Segura, G.

2018-03-01

We present seeing-limited narrow-band mid-IR GTC/CanariCam images of the spatially extended fullerene-containing planetary nebula (PN) IC 418. The narrow-band images cover the C60 fullerene band at 17.4 μm, the polycyclic aromatic hydrocarbon like (PAH-like) feature at 11.3 μm, the broad 9–13 μm feature, and their adjacent continua at 9.8 and 20.5 μm. We study the relative spatial distribution of these complex species, all detected in the Spitzer and Infrared Space Observatory spectra of IC 418, with the aim of getting observational constraints to the formation process of fullerenes in H-rich circumstellar environments. A similar ring-like extended structure is seen in all narrow-band filters, except in the dust continuum emission at 9.8 μm, which peaks closer to the central star. The continuum-subtracted images display a clear ring-like extended structure for the carrier of the broad 9–13 μm emission, while the spatial distribution of the (PAH-like) 11.3 μm emission is not so well defined. Interestingly, a residual C60 17.4 μm emission (at about 4σ from the sky background) is seen when subtracting the dust continuum emission at 20.5 μm. This residual C60 emission, if real, might have several interpretations, the most exciting being perhaps that other fullerene-based species like hydrogenated fullerenes with very low H-content may contribute to the observed 17.4 μm emission. We conclude that higher sensitivity mid-IR images and spatially resolved spectroscopic observations (especially in the Q-band) are necessary to get some clues about fullerene formation in PNe.

Lyapunov-based constrained engine torque control using electronic throttle and variable cam timing

NARCIS (Netherlands)

Feru, E.; Lazar, M.; Gielen, R.H.; Kolmanovsky, I.V.; Di Cairano, S.

2012-01-01

In this paper, predictive control of a spark ignition engine equipped with an electronic throttle and a variable cam timing actuator is considered. The objective is to adjust the throttle angle and the engine cam timing in order to reduce the exhaust gas emissions while maintaining fast and

Information management and complementary alternative medicine: the anatomy of information about CAMs through PubMed.

Science.gov (United States)

Corrao, Salvatore; Argano, Christiano; Colomba, Daniela; Ippolito, Calogero; Gargano, Vincenzo; Arcoraci, Vincenzo; Licata, Giuseppe

2013-10-01

In recent years, there has been a growing interest about complementary and alternative medicine (CAM), and the use of CAM interventions has become more common among people. For these reasons, health professionals must be able to effectively manage information in this field of knowledge according to an evidence-based point of view. This study assessed the anatomy of the available information about CAMs using PubMed, to give practical instructions to manage information in this field. We also analyzed the anatomy of information according to each alternative medicine branch, narrow and broad search methods, subset filters for indexed-for-Medline and non-indexed citations, and different publication types including randomized controlled trials (RCTs) and meta-analyses. Our results demonstrated that the use of CAMs subset (supplied by PubMed search engine) leads to a great number of citations determining an information overload. Our data reveal that it would be more useful to search for the CAM separately, identifying specific items and study design. Moreover, we found the largest number of randomized clinical trials and meta-analyses related to herbal medicine and acupuncture, neither RCTs nor meta-analyses were available for bach and flower remedies, auriculoacupuncture, iridology, and pranotherapy. For the first time, our study gives a comprehensive view of the anatomy of information regarding CAMs and each branch of them. We suggest a methodological approach to face with searching information about this emerging issue from an evidence-based point of view. Finally, our data pointed out some "grey zones" since neither RCTs nor meta-analyses were available for some CAMs.

Calibrating the ChemCam LIBS for Carbonate Minerals on Mars

Science.gov (United States)

Wiens, Roger C.; Clegg, Samuel M.; Ollila, Ann M.; Barefield, James E.; Lanza, Nina; Newsom, Horton E.

2009-01-01

The ChemCam instrument suite on board the NASA Mars Science Laboratory (MSL) rover includes the first LIBS instrument for extraterrestrial applications. Here we examine carbonate minerals in a simulated martian environment using the LIDS technique in order to better understand the in situ signature of these materials on Mars. Both chemical composition and rock type are determined using multivariate analysis (MVA) techniques. Composition is confirmed using scanning electron microscopy (SEM) techniques. Our initial results suggest that ChemCam can recognize and differentiate between carbonate materials on Mars.

A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world.

Science.gov (United States)

Yang, Xiaohan; Cushman, John C; Borland, Anne M; Edwards, Erika J; Wullschleger, Stan D; Tuskan, Gerald A; Owen, Nick A; Griffiths, Howard; Smith, J Andrew C; De Paoli, Henrique C; Weston, David J; Cottingham, Robert; Hartwell, James; Davis, Sarah C; Silvera, Katia; Ming, Ray; Schlauch, Karen; Abraham, Paul; Stewart, J Ryan; Guo, Hao-Bo; Albion, Rebecca; Ha, Jungmin; Lim, Sung Don; Wone, Bernard W M; Yim, Won Cheol; Garcia, Travis; Mayer, Jesse A; Petereit, Juli; Nair, Sujithkumar S; Casey, Erin; Hettich, Robert L; Ceusters, Johan; Ranjan, Priya; Palla, Kaitlin J; Yin, Hengfu; Reyes-García, Casandra; Andrade, José Luis; Freschi, Luciano; Beltrán, Juan D; Dever, Louisa V; Boxall, Susanna F; Waller, Jade; Davies, Jack; Bupphada, Phaitun; Kadu, Nirja; Winter, Klaus; Sage, Rowan F; Aguilar, Cristobal N; Schmutz, Jeremy; Jenkins, Jerry; Holtum, Joseph A M

2015-08-01

Crassulacean acid metabolism (CAM) is a specialized mode of photosynthesis that features nocturnal CO2 uptake, facilitates increased water-use efficiency (WUE), and enables CAM plants to inhabit water-limited environments such as semi-arid deserts or seasonally dry forests. Human population growth and global climate change now present challenges for agricultural production systems to increase food, feed, forage, fiber, and fuel production. One approach to meet these challenges is to increase reliance on CAM crops, such as Agave and Opuntia, for biomass production on semi-arid, abandoned, marginal, or degraded agricultural lands. Major research efforts are now underway to assess the productivity of CAM crop species and to harness the WUE of CAM by engineering this pathway into existing food, feed, and bioenergy crops. An improved understanding of CAM has potential for high returns on research investment. To exploit the potential of CAM crops and CAM bioengineering, it will be necessary to elucidate the evolution, genomic features, and regulatory mechanisms of CAM. Field trials and predictive models will be required to assess the productivity of CAM crops, while new synthetic biology approaches need to be developed for CAM engineering. Infrastructure will be needed for CAM model systems, field trials, mutant collections, and data management. © 2015 ORNL/UT-Battelle New Phytologist © 2015 New Phytologist Trust.

DYNAMIC ANALYSIS OF A CRIMPING DEVICE WITH MULTIPLE CAMS USING MSC ADAMS II

Directory of Open Access Journals (Sweden)

Gheorghe Popescu

2012-05-01

Full Text Available Through the present paper, the author presents the results of the dynamic analysis with MSC ADAMS of the mechanism with a crimping device with 12 tightening cams, designed and used in the technological process of assembly of the indigenous electrical detonators. In this sense, the mechanism with multiple cams is considered a mechanical system and is treated as an assembly of rigid bodies connected by mechanical connections and elastic elements. For shaping and simulation of the mechanism with multiple cams using ADAMS program, the author got through the following stages: construction of the pattern, its testing and simulation, validation, finishing, parametrization, optimization of the pattern.

Psychological and behavioral mechanisms influencing the use of complementary and alternative medicine (CAM) in cancer patients.

Science.gov (United States)

Hirai, K; Komura, K; Tokoro, A; Kuromaru, T; Ohshima, A; Ito, T; Sumiyoshi, Y; Hyodo, I

2008-01-01

This study explored the psychological and behavioral mechanisms of complementary and alternative medicine (CAM) use in Japanese cancer patients using two applied behavioral models, the transtheoretical model (TTM), and theory of planned behavior (TPB). Questionnaires were distributed to 1100 patients at three cancer treatment facilities in Japan and data on 521 cancer patients were used in the final analysis. The questionnaire included items based on TTM and TPB variables, as well as three psychological batteries. According to the TTM, 88 patients (17%) were in precontemplation, 226 (43%) in contemplation, 33 (6%) in preparation, 71 (14%) in action, and 103 (20%) in maintenance. The model derived from structural equation modeling revealed that the stage of CAM use was significantly affected by the pros, cons, expectation from family, norms of medical staff, use of chemotherapy, period from diagnosis, and place of treatment. The primary factor for the stage of CAM use was the expectation from family. The findings revealed the existence of a number of psychologically induced potential CAM users, and psychological variables including positive attitude for CAM use and perceived family expectation greatly influence CAM use in cancer patients.

CAM, free speech, and the British legal system: overstepping the mark?

Science.gov (United States)

Milgrom, Lionel R

2009-10-01

The British Chiropractic Association recently won a libel case against the science writer and CAM 'skeptic' Dr Simon Singh for publishing an article in a British newspaper in which he accused them of promoting 'bogus' treatments. This has ignited a campaign in the UK to 'keep the libel laws out of science'. In this article, the tension between media freedom of expression and defamation law is examined, and possible ramifications for CAM in the UK explored.

AffectCam : arousal- augmented sensecam for richer recall of episodic memories

OpenAIRE

Sas, Corina; Fratczak, Thomasz; Rees, Matthew; Gellersen, Hans; Kalnikaitė, Vaiva; Coman, Alina; Höök, Kristina

2013-01-01

This paper describes the design and evaluation of AffectCam, a wearable system integrating SenseCam and BodyMedia SenseWear for capturing galvanic skin response as a measure of bodily arousal. AffectCam’s algorithms use arousal as a filtering mechanism for selecting the most personally relevant photos captured during people’s ordinary daily life, i.e. high arousal photos. We discuss initial findings showing that emotional arousal does improve the quality of memory recall associated with emoti...

Color change of CAD-CAM materials and composite resin cements after thermocycling.

Science.gov (United States)

Gürdal, Isil; Atay, Ayse; Eichberger, Marlis; Cal, Ebru; Üsümez, Aslihan; Stawarczyk, Bogna

2018-04-24

The color of resin cements and computer-aided-design and computer-aided-manufacturing (CAD-CAM) restorations may change with aging. The purpose of this in vitro study was to analyze the influence of thermocycling on the color of CAD-CAM materials with underlying resin cement. Seven different CAD-CAM materials, composite resins and glass-ceramics were cut into 0.7-mm and 1.2-mm thicknesses (n=10) and cemented with a dual-polymerizing resin cement, a light-polymerizing resin cement, and a preheated composite resin (N=420). Color values were measured by using spectrophotometry. Specimens were subjected to thermocycling (5°C and 55°C; 5000 cycles). The measured color difference (ΔE) data were analyzed by using descriptive statistics. Normality of data distribution was tested by using the Kolmogorov-Smirnov test. Three-way and 1-way ANOVA followed by the Scheffé post-hoc test and unpaired 2-sample Student t test were computed to determine the significant differences among the tested parameters (α=.05). ΔE values were significantly influenced by the CAD-CAM material (η p 2 =0.85, Pcement (η P 2 =0.03, P=.003) but were not influenced by thickness (P=.179). Significant interactions were present among thickness, cement, and CAD-CAM materials (Pcement showed significantly lower ΔE values than the preheated composite resin (P=.003). Restoration materials and composite resin cement types used for cementation influence the amount of color change due to aging. Copyright © 2018 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Use of complementary and alternative medicine (CAM) by parents in their children and adolescents with epilepsy - Prevelance, predictors and parents' assessment.

Science.gov (United States)

Hartmann, Nicole; Neininger, Martina P; Bernhard, Matthias K; Syrbe, Steffen; Nickel, Petra; Merkenschlager, Andreas; Kiess, Wieland; Bertsche, Thilo; Bertsche, Astrid

2016-01-01

The use of complementary and alternative medicine (CAM) is popular. Parents of children suffering from epilepsy may also consider administering CAM to their children. Systematic data about frequency of and motivations for CAM use, however, are scarce. In a university hospital's neuropaediatric department parents of patients aged 0-18 years suffering from epilepsy were consecutively invited to take part in a structured interview during 4 months in 2014. Of the invited parents, 164/165 (99%) agreed to participate. From those, 21/164 (13%) stated that they used CAM in their child. The highest independent predictive value of CAM use was the occurrence of adverse drug events (ADE) of anticonvulsants as judged by parents. Patients affected by ADE had a 5.6 higher chance of receiving CAM compared to patients without ADE. Most commonly used were homeopathy (14/21, 67%) and osteopathy (12/21, 57%). The internet was the most frequently used source of information (14/21, 67%). Of the parents, 10/21 (48%) described positive effects of CAM on seizure frequency, 12/21 (57%) on general condition of their child, and 20/21 (95%) wished to continue CAM for epilepsy therapy. From the non-users of CAM, 91/143 (66%) expressed the desire to learn more about CAM for epilepsy therapy. Our study was performed in a university hospital in a large urban city in Eastern Germany. CAM user rates can differ in other parts of Germany and Europe, in other institutions and for chronic diseases other than epilepsy. The main reason for CAM use was the occurrence of ADE of anticonvulsants. More than half of the parents saw a benefit of CAM for their children. Almost all parents wished to continue CAM use, even those who did not see concrete positive effects. Copyright © 2015 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

Chairside CAD/CAM materials. Part 2: Flexural strength testing.

Science.gov (United States)

Wendler, Michael; Belli, Renan; Petschelt, Anselm; Mevec, Daniel; Harrer, Walter; Lube, Tanja; Danzer, Robert; Lohbauer, Ulrich

2017-01-01

Strength is one of the preferred parameters used in dentistry for determining clinical indication of dental restoratives. However, small dimensions of CAD/CAM blocks limit reliable measurements with standardized uniaxial bending tests. The objective of this study was to introduce the ball-on-three-ball (B3B) biaxial strength test for dental for small CAD/CAM block in the context of the size effect on strength predicted by the Weibull theory. Eight representative chairside CAD/CAM materials ranging from polycrystalline zirconia (e.max ZirCAD, Ivoclar-Vivadent), reinforced glasses (Vitablocs Mark II, VITA; Empress CAD, Ivoclar-Vivadent) and glass-ceramics (e.max CAD, Ivoclar-Vivadent; Suprinity, VITA; Celtra Duo, Dentsply) to hybrid materials (Enamic, VITA; Lava Ultimate, 3M ESPE) have been selected. Specimens were prepared with highly polished surfaces in rectangular plate (12×12×1.2mm 3 ) or round disc (Ø=12mm, thickness=1.2mm) geometries. Specimens were tested using the B3B assembly and the biaxial strength was determined using calculations derived from finite element analyses of the respective stress fields. Size effects on strength were determined based on results from 4-point-bending specimens. A good agreement was found between the biaxial strength results for the different geometries (plates vs. discs) using the B3B test. Strength values ranged from 110.9MPa (Vitablocs Mark II) to 1303.21MPa (e.max ZirCAD). The strength dependency on specimen size was demonstrated through the calculated effective volume/surface. The B3B test has shown to be a reliable and simple method for determining the biaxial strength restorative materials supplied as small CAD/CAM blocks. A flexible solution was made available for the B3B test in the rectangular plate geometry. Copyright © 2016 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

Dental calculus detection using the VistaCam.

Science.gov (United States)

Shakibaie, Fardad; Walsh, Laurence J

2016-12-01

The VistaCam® intra-oral camera system (Dürr Dental, Bietigheim-Bissingen, Germany) is a fluorescence system using light emitting diodes that produce a 405-nm violet light. This wavelength has potential application for detection of dental calculus based on red emissions from porphyrin molecules. This study assessed the digital scores obtained for both supragingival and subgingival calculus on 60 extracted teeth and compared these with lesions of dental caries. It has also examined the effect of saliva and blood on the fluorescence readings for dental calculus. VistaCam fluorescence scores for both supragingival (1.7-3.3) and subgingival calculus (1.3-2.4) were higher than those for sound root surfaces (0.9-1.1) and dental caries (0.9-2.2) ( p  calculus samples were not affected by the presence of saliva or blood. These results suggest that the use of violet light fluorescence could be a possible adjunct to clinical examination for deposits of dental calculus.

Efficacy, tolerability, and safety of non-pharmacological therapies for chronic pain: An umbrella review on various CAM approaches.

Science.gov (United States)

Houzé, Bérengère; El-Khatib, Héjar; Arbour, Caroline

2017-10-03

Complementary and alternative medicine (CAM) therapies may be used as a non-pharmacological approach to chronic pain management. While hundreds of trials about individual CAM modality have been conducted, a comprehensive overview of their results is currently lacking for pain clinicians and researchers. This umbrella review synthesized the quality of meta-analytic evidence supporting the efficacy, tolerability and safety of CAM therapies for the management of chronic pain. MEDLINE, EMBASE, CINAHL, and CENTRAL were searched from October 1991 to November 2016. Reviews of clinical trials (randomized and non-randomized) with meta-analysis investigating the utility of any CAM modality for chronic pain were eligible. Pain relief post-intervention was the main outcome and secondary outcomes included patients' adherence and incidence of adverse effects during CAM protocol. Twenty-six reviews (207 clinical trials, >12,000 participants) about 18 CAM modalities, falling under natural products, mind and body practices or other complementary health approaches were included. Inhaled cannabis, graded motor imagery, and Compound Kushen injection (a form of Chinese medicine) were found the most efficient (with moderate-to-high effect sizes and low heterogeneity) and tolerable (≥80% of adherence to study protocols) for chronic pain relief. When reported, adverse effects related to these CAM were minor. Although several CAM were found effective for chronic pain relief, it remains unclear when these modalities are a reasonable choice against or in conjunction with mainstream treatments. In that sense, future research with a clear emphasis on concurrent evaluation of CAM overall efficacy and patient adherence/tolerance is needed. Copyright © 2017 Elsevier Inc. All rights reserved.

CAM and Cell Fate Targeting: Molecular and Energetic Insights into Cell Growth and Differentiation

Directory of Open Access Journals (Sweden)

Carlo Ventura

2005-01-01

Full Text Available Evidence-based medicine is switching from the analysis of single diseases at a time toward an integrated assessment of a diseased person. Complementary and alternative medicine (CAM offers multiple holistic approaches, including osteopathy, homeopathy, chiropractic, acupuncture, herbal and energy medicine and meditation, all potentially impacting on major human diseases. It is now becoming evident that acupuncture can modify the expression of different endorphin genes and the expression of genes encoding for crucial transcription factors in cellular homeostasis. Extremely low frequency magnetic fields have been found to prime the commitment to a myocardial lineage in mouse embryonic stem cells, suggesting that magnetic energy may direct stem cell differentiation into specific cellular phenotypes without the aid of gene transfer technologies. This finding may pave the way to novel approaches in tissue engineering and regeneration. Different ginseng extracts have been shown to modulate growth and differentiation in pluripotent cells and to exert wound-healing and antitumor effects through opposing activities on the vascular system, prompting the hypothesis that ancient compounds may be the target for new logics in cell therapy. These observations and the subtle entanglement among different CAM systems suggest that CAM modalities may deeply affect both the signaling and transcriptional level of cellular homeostasis. Such a perception holds promises for a new era in CAM, prompting reproducible documentation of biological responses to CAM-related strategies and compounds. To this end, functional genomics and proteomics and the comprehension of the cell signaling networks may substantially contribute to the development of a molecular evidence–based CAM.

The use of CAM and conventional treatments among primary care consulters with chronic musculoskeletal pain

OpenAIRE

Lewis Martyn; Croft Peter; Artus Majid

2007-01-01

Abstract Background Chronic musculoskeletal pain is the single most cited reason for use of complementary and alternative medicine (CAM). Primary care is the most frequent conventional medical service used by patients with pain in the UK. We are unaware, however, of a direct evidence of the extent of CAM use by primary care patients, and how successful they perceive it to be. Methods Aims and objectives To determine CAM use among patients with chronic musculoskeletal pain who have consulted a...

Decisions to use complementary and alternative medicine (CAM) by male cancer patients: information-seeking roles and types of evidence used

Science.gov (United States)

Evans, Maggie; Shaw, Alison; Thompson, Elizabeth A; Falk, Stephen; Turton, Pat; Thompson, Trevor; Sharp, Deborah

2007-01-01

Background Complementary and Alternative Medicine (CAM) is increasingly popular with cancer patients and yet information provision or discussion about CAM by health professionals remains low. Previous research suggests that patients may fear clinicians' 'disapproval' if they raise the subject of CAM, and turn to other sources to acquire information about CAM. However, little empirical research has been conducted into how cancer patients acquire, and, more importantly evaluate CAM information before deciding which CAM therapies to try. Methods Qualitative study, comprising semi-structured interviews with 43 male cancer patients of varying ages, cancer type and stage of illness, 34 of whom had used CAM. They were recruited from a range of NHS and non-NHS settings in Bristol, England. Results As a result of the lack of CAM information from health professionals, men in this study became either 'pro-active seekers' or 'passive recipients' of such information. Their main information resource was the 'lay referral' network of family, friends and acquaintances, especially females. 'Traditional' information sources, including books, magazines, leaflets and the media were popular, more so in fact than the internet. Views on the internet ranged from enthusiasm or healthy scepticism through to caution or disinterest. CAM information was generally regarded as 'empowering' as it broadened treatment and self-care options. A minority of participants were information averse fearing additional choices that might disrupt their fragile ability to cope. There was general consensus that CAM information should be available via the NHS, to give it a 'stamp of approval', which combined with guidance from informed health professionals, could help patients to make 'guided' choices. However, a small minority of these men valued the independence of CAM from the NHS and deliberately sought 'alternative' information sources and treatment options. Men were selective in identifying particular

Does complementary and alternative medicine (CAM) use reduce negative life impact of headaches for chronic migraineurs? A national survey.

Science.gov (United States)

Lee, Jieun; Bhowmick, Amrita; Wachholtz, Amy

2016-01-01

Chronic migraine is a disabling condition that impacts multiple aspects of migraineurs' lives. Although pharmacological treatments can help to treat the pain associated with migraine headache, chronic migraineurs often experience side-effects of pharmacological treatments. Those experiences may contribute to the observed growth in complementary and alternative medicine (CAM) use among migraineurs. Relatively little is known about the patterns of CAM treatment and the characteristics of chronic migraineurs. Therefore, the purpose of the present study is to investigate the characteristics of chronic migraineurs who use CAM treatment and the relationship among satisfaction with current CAM use, negative life impact, migraine outcomes, and psychiatric comorbidities among chronic migraineurs. 2907 participants were recruited from a well-known online migraine headache resource. All participants were US adults aged 18 years or older. Migraineurs are referred to this website through various routes (e.g., referral from healthcare providers, internet search, obtaining information from research papers, personal invitation from other users, and information shared on social media etc.). Participants completed a 30-min self-report-survey in the spring of 2014. Almost half of the participants reported that they are currently using more than three different CAM treatments even though the majority of the participants reported neutral or dissatisfied with their current CAM treatment. Chronic migraineurs who use CAM treatments were more likely to experience prolonged or frequent migraine headaches (p = .018, η(2) = .0021), and experience greater negative life impact from their headaches (p = .000, η(2) = .0172) compared to non-CAM users. CAM treatment satisfaction was inversely related to the number of psychiatric comorbidities, frequency of migraines, and number of migraine symptoms (p's < .05). However, CAM treatment satisfaction was more strongly correlated with

Fabricating CAD/CAM Implant-Retained Mandibular Bar Overdentures: A Clinical and Technical Overview

Directory of Open Access Journals (Sweden)

Chui Ling Goo

2017-01-01

Full Text Available This report describes the clinical and technical aspects in the oral rehabilitation of an edentulous patient with knife-edge ridge at the mandibular anterior edentulous region, using implant-retained overdentures. The application of computer-aided design and computer-aided manufacturing (CAD/CAM in the fabrication of the overdenture framework simplifies the laboratory process of the implant prostheses. The Nobel Procera CAD/CAM System was utilised to produce a lightweight titanium overdenture bar with locator attachments. It is proposed that the digital workflow of CAD/CAM milled implant overdenture bar allows us to avoid numerous technical steps and possibility of casting errors involved in the conventional casting of such bars.

Patients’ views of CAM as spiritual practice

DEFF Research Database (Denmark)

Ulrich, Anita; Evron, Lotte; Ostenfeld-Rosenthal, Ann

2011-01-01

significantly elaborated upon in narratives by four female participants to warrant more detailed consideration and analysis. Conclusion: It is suggested that for some cancer patients CAM may function, not just as a treatment for cancer related symptoms and side effects, but also as a form of spiritual practice...

performance characteristics of a cam turning attachment

African Journals Online (AJOL)

Dr Obe

ABSTRACT. A modification of a cylindrical turning unit has been done to give a non- cylindrical turning attachment for production of irregular shapes, like cams on the lathe machine. To assess the performance of the attachment, cutting forces have been measured using a 'Sigma' Cutting Tool. Dynamometer. Furthermore ...

[Detection and clinical value of epithelial cellular adhesion molecule (EpCAM) mRNA positive circulating tumor cells in metastatic breast cancer].

Science.gov (United States)

Yan, Ying; Cheng, Jian-ping; Di, Li-jun; Song, Guo-hong; Ren, Jun

2012-04-18

To test for circulating tumor cells (CTCs) relying on epithelial cellular adhesion molecule (EpCAM) expression in metastatic breast cancer by quantitative real-time reverse transcription-PCR. In the study,47 metastatic breast cancer patients were evaluated by quantitative real-time PCR for detecting EpCAM mRNA. In addition, analyses were carried out for their correlation with patients' clinicopathologic features, response, and the time to progression (TTP). The sensitivity of EpCAM mRNA in the metastatic breast cancer patients was about 40%. However, the specificity of EpCAM mRNA for 20 healthy controls was 100%. TTP was calculated, and compared with that between EpCAM mRNA-positive and EpCAM mRNA-negative groups. For the retrospective study, the median TTP was 7.1 months and 11.1 months (P=0.013) for patients with EpCAM mRNA-positive and EpCAM mRNA-negative, respectively, after the first cycle chemotherapy. Moreover, a statistically significant correlation was demonstrated between EpCAM mRNA and TTP in patients who underwent the first or the second-line chemotherapy (P=0.018), but there was no significance in the patients pretreated with two or more previous chemotherapy lines (P=0.471). This study provides evidence of the presence of EpCAM mRNA in approximately 40% of patients with metastatic breast cancer. There is a strong correlation between EpCAM mRNA results after the first cycle therapy and TTP in metastatic breast cancer patients, and EpCAM mRNA positive after chemotherapy may predict shorter TTP.

Hip Imaging in Athletes: Sports Imaging Series.

Science.gov (United States)

Agten, Christoph A; Sutter, Reto; Buck, Florian M; Pfirrmann, Christian W A

2016-08-01

Hip or groin pain in athletes is common and clinical presentation is often nonspecific. Imaging is a very important diagnostic step in the work-up of athletes with hip pain. This review article provides an overview on hip biomechanics and discusses strategies for hip imaging modalities such as radiography, ultrasonography, computed tomography, and magnetic resonance (MR) imaging (MR arthrography and traction MR arthrography). The authors explain current concepts of femoroacetabular impingement and the problem of high prevalence of cam- and pincer-type morphology in asymptomatic persons. With the main focus on MR imaging, the authors present abnormalities of the hip joint and the surrounding soft tissues that can occur in athletes: intraarticular and extraarticular hip impingement syndromes, labral and cartilage disease, microinstability of the hip, myotendinous injuries, and athletic pubalgia. (©) RSNA, 2016.

CAM visual stimulation with conventional method of occlusion treatment in amblyopia: a randomized clinical trial

Directory of Open Access Journals (Sweden)

Ali Reza Jafari

2014-04-01

Conclusion: Using of CAM visual stimulation along with conventional occlusion will further improve visual acuity and stereopsis in amblyopic children. These findings recommended the CAM visual stimulation as an accompanying and complementary method in amblyopia treatment.

SUZAKU OBSERVATIONS OF SUBHALOS IN THE COMA CLUSTER

Energy Technology Data Exchange (ETDEWEB)

Sasaki, Toru; Matsushita, Kyoko; Sato, Kosuke [Department of Physics, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan); Okabe, Nobuhiro, E-mail: j1213703@ed.tus.ac.jp, E-mail: matusita@rs.kagu.tus.ac.jp [Department of Physical Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526 (Japan)

2015-06-10

We observed three massive subhalos in the Coma cluster with Suzaku. These subhalos, labeled “ID 1,” “ID 2,” and “ID 32,” were detected with a weak-lensing survey using Subaru/Suprime-Cam, and are located at the projected distances of 1.4 r{sub 500}, 1.2 r{sub 500}, and 1.6 r{sub 500} from the center of the Coma cluster, respectively. The subhalo “ID 1” has a compact X-ray excess emission close to the center of the weak-lensing mass contour, and the gas mass to weak-lensing mass ratio is about 0.001. The temperature of the emission is about 3 keV, which is slightly lower than that of the surrounding intracluster medium (ICM) and that expected for the temperature versus mass relation of clusters of galaxies. The subhalo “ID 32” shows an excess emission whose peak is shifted toward the opposite direction from the center of the Coma cluster. The gas mass to weak-lensing mass ratio is also about 0.001, which is significantly smaller than regular galaxy groups. The temperature of the excess is about 0.5 keV and significantly lower than that of the surrounding ICM and far from the temperature versus mass relation of clusters. However, there is no significant excess X-ray emission in the “ID 2” subhalo. Assuming an infall velocity of about 2000 km s{sup −1}, at the border of the excess X-ray emission, the ram pressures for “ID 1” and “ID 32” are comparable to the gravitational restoring force per area. We also studied the effect of the Kelvin–Helmholtz instability to strip the gas. Although we found X-ray clumps associated with the weak-lensing subhalos, their X-ray luminosities are much lower than the total ICM luminosity in the cluster outskirts.

Planetary Nebulae and their parent stellar populations. Tracing the mass assembly of M87 and Intracluster light in the Virgo cluster core

Science.gov (United States)

Arnaboldi, Magda; Longobardi, Alessia; Gerhard, Ortwin

2016-08-01

The diffuse extended outer regions of galaxies are hard to study because they are faint, with typical surface brightness of 1% of the dark night sky. We can tackle this problem by using resolved star tracers which remain visible at large distances from the galaxy centers. This article describes the use of Planetary Nebulae as tracers and the calibration of their properties as indicators of the star formation history, mean age and metallicity of the parent stars in the Milky Way and Local Group galaxies. We then report on the results from a deep, extended, planetary nebulae survey in a 0.5 deg2 region centered on the brightest cluster galaxy NGC 4486 (M87) in the Virgo cluster core, carried out with SuprimeCam@Subaru and FLAMES-GIRAFFE@VLT. Two planetary nebulae populations are identified out to 150 kpc distance from the center of M87. One population is associated with the M87 halo and the second one with the intracluster light in the Virgo cluster core. They have different line-of-sight velocity and spatial distributions, as well as different planetary nebulae specific frequencies and luminosity functions. The intracluster planetary nebulae in the surveyed region correspond to a luminosity of four times the luminosity of the Large Magellanic Cloud. The M87 halo planetary nebulae trace an older, more metal-rich, parent stellar population. A substructure detected in the projected phase-space of the line-of-sight velocity vs. major axis distance for the M87 halo planetary nebulae provides evidence for the recent accretion event of a satellite galaxy with luminosity twice that of M33. The satellite stars were tidally stripped about 1 Gyr ago, and reached apocenter at a major axis distance of 60-90 kpc from the center of M87. The M87 halo is still growing significantly at the distances where the substructure is detected.

Treatment Expectations for CAM Interventions in Pediatric Chronic Pain Patients and their Parents

Directory of Open Access Journals (Sweden)

Jennie C. I. Tsao

2005-01-01

Full Text Available Patient expectations regarding complementary and alternative medicine (CAM interventions have important implications for treatment adherence, attrition and clinical outcome. Little is known, however, about parent and child treatment expectations regarding CAM approaches for pediatric chronic pain problems. The present study examined ratings of the expected benefits of CAM (i.e. hypnosis, massage, acupuncture, yoga and relaxation and conventional medicine (i.e. medications, surgery interventions in 45 children (32 girls; mean age = 13.8 years ± 2.5 and parents (39 mothers presenting for treatment at a specialty clinic for chronic pediatric pain. Among children, medications and relaxation were expected to be significantly more helpful than the remaining approaches (P < 0.01. However, children expected the three lowest rated interventions, acupuncture, surgery and hypnosis, to be of equal benefit. Results among parents were similar to those found in children but there were fewer significant differences between ratings of the various interventions. Only surgery was expected by parents to be significantly less helpful than the other approaches (P < 0.01. When parent and child perceptions were compared, parents expected hypnosis, acupuncture and yoga, to be more beneficial than did children, whereas children expected surgery to be more helpful than did parents (P < 0.01. Overall, children expected the benefits of CAM to be fairly low with parents' expectations only somewhat more positive. The current findings suggest that educational efforts directed at enhancing treatment expectations regarding CAM, particularly among children with chronic pain, are warranted.

Chick ex ovo culture and ex ovo CAM assay: how it really works.

Science.gov (United States)

Dohle, Daniel S; Pasa, Susanne D; Gustmann, Sebastian; Laub, Markus; Wissler, Josef H; Jennissen, Herbert P; Dünker, Nicole

2009-11-30

Chicken eggs in the early phase of breeding are between in vitro and in vivo systems and provide a vascular test environment not only to study angiogenesis but also to study tumorigenesis. After the chick chorioallantoic membrane (CAM) has developed, its blood vessel network can be easily accessed, manipulated and observed and therefore provides an optimal setting for angiogenesis assays. Since the lymphoid system is not fully developed until late stages of incubation, the chick embryo serves as a naturally immunodeficient host capable of sustaining grafted tissues and cells without species-specific restrictions. In addition to nurturing developing allo- and xenografts, the CAM blood vessel network provides a uniquely supportive environment for tumor cell intravasation, dissemination, and vascular arrest and a repository where arrested cells extravasate to form micro metastatic foci. For experimental purposes, in most of the recent studies the CAM was exposed by cutting a window through the egg shell and experiments were carried out in ovo, resulting in significant limitations in the accessibility of the CAM and possibilities for observation and photo documentation of effects. When shell-less cultures of the chick embryo were used(1-4), no experimental details were provided and, if published at all, the survival rates of these cultures were low. We refined the method of ex ovo culture of chick embryos significantly by introducing a rationally controlled extrusion of the egg content. These ex ovo cultures enhance the accessibility of the CAM and chick embryo, enabling easy in vivo documentation of effects and facilitating experimental manipulation of the embryo. This allows the successful application to a large number of scientific questions: (1) As an improved angiogenesis assay(5,6), (2) an experimental set up for facilitated injections in the vitreous of the chick embryo eye(7-9), (3) as a test environment for dissemination and intravasation of dispersed tumor

Usage of Complementary and Alternative Medicine (CAM) among osteoarthritis patients attending an urban multi-specialist hospital in Lagos, Nigeria.

Science.gov (United States)

Obalum, D C; Ogo, C N

2011-03-01

Osteoarthritis (OA), a chronic degenerative disease of synovial joints is characterised by pain and stiffness. Aim of treatment is pain relief. Complementary and alternative medicine (CAM) refers to practices which are not an integral part of orthodox medicine. To determine the pattern of usage of CAM among OA patients in Nigeria. Consecutive patients with OA attending orthopaedic clinic of Havana Specialist Hospital, Lagos, Nigeria were interviewed over a 6- month period st st of 1 May to 31 October 2007 on usage of CAM. Structured and open-ended questions were used. Demographic data, duration of OA and treatment as well as compliance to orthodox medications were documented. One hundred and sixty four patients were studied.120 (73.25%) were females and 44(26.89%) were males. Respondents age range between 35-74 years. 66(40.2%) patients used CAM. 35(53.0%) had done so before presenting to the hospital. The most commonly used CAM were herbal products used by 50(75.8%) of CAM users. Among herbal product users, 74.0% used non- specific local products, 30.0% used ginger, 36.0% used garlic and 28.0% used Aloe Vera. Among CAM users, 35(53.0%) used local embrocation and massage, 10(15.2%) used spiritual methods. There was no significant difference in demographics, clinical characteristics and pain control among CAM users and non-users. Many OA patients receiving orthodox therapy also use CAM. Medical doctors need to keep a wary eye on CAM usage among patients and enquire about this health-seeking behaviour in order to educate them on possible drug interactions, adverse effects and long term complications.

"We make choices we think are going to save us": Debate and stance identification for online breast cancer CAM discussions.

Science.gov (United States)

Zhang, Shaodian; Qiu, Lin; Chen, Frank; Zhang, Weinan; Yu, Yong; Elhadad, Noémie

2017-04-01

Patients discuss complementary and alternative medicine (CAM) in online health communities. Sometimes, patients' conflicting opinions toward CAM-related issues trigger debates in the community. The objectives of this paper are to identify such debates, identify controversial CAM therapies in a popular online breast cancer community, as well as patients' stances towards them. To scale our analysis, we trained a set of classifiers. We first constructed a supervised classifier based on a long short-term memory neural network (LSTM) stacked over a convolutional neural network (CNN) to detect automatically CAM-related debates from a popular breast cancer forum. Members' stances in these debates were also identified by a CNN-based classifier. Finally, posts automatically flagged as debates by the classifier were analyzed to explore which specific CAM therapies trigger debates more often than others. Our methods are able to detect CAM debates with F score of 77%, and identify stances with F score of 70%. The debate classifier identified about 1/6 of all CAM-related posts as debate. About 60% of CAM-related debate posts represent the supportive stance toward CAM usage. Qualitative analysis shows that some specific therapies, such as Gerson therapy and usage of laetrile, trigger debates frequently among members of the breast cancer community. This study demonstrates that neural networks can effectively locate debates on usage and effectiveness of controversial CAM therapies, and can help make sense of patients' opinions on such issues under dispute. As to CAM for breast cancer, perceptions of their effectiveness vary among patients. Many of the specific therapies trigger debates frequently and are worth more exploration in future work.

The synaptic cell adhesion molecule, SynCAM1, mediates astrocyte-to-astrocyte and astrocyte-to-GnRH neuron adhesiveness in the mouse hypothalamus.

Science.gov (United States)

Sandau, Ursula S; Mungenast, Alison E; McCarthy, Jack; Biederer, Thomas; Corfas, Gabriel; Ojeda, Sergio R

2011-06-01

We previously identified synaptic cell adhesion molecule 1 (SynCAM1) as a component of a genetic network involved in the hypothalamic control of female puberty. Although it is well established that SynCAM1 is a synaptic adhesion molecule, its contribution to hypothalamic function is unknown. Here we show that, in addition to the expected neuronal localization illustrated by its presence in GnRH neurons, SynCAM1 is expressed in hypothalamic astrocytes. Cell adhesion assays indicated that SynCAM is recognized by both GnRH neurons and astrocytes as an adhesive partner and promotes cell-cell adhesiveness via homophilic, extracellular domain-mediated interactions. Alternative splicing of the SynCAM1 primary mRNA transcript yields four mRNAs encoding membrane-spanning SynCAM1 isoforms. Variants 1 and 4 are predicted to be both N and O glycosylated. Hypothalamic astrocytes and GnRH-producing GT1-7 cells express mainly isoform 4 mRNA, and sequential N- and O-deglycosylation of proteins extracted from these cells yields progressively smaller SynCAM1 species, indicating that isoform 4 is the predominant SynCAM1 variant expressed in astrocytes and GT1-7 cells. Neither cell type expresses the products of two other SynCAM genes (SynCAM2 and SynCAM3), suggesting that SynCAM-mediated astrocyte-astrocyte and astrocyte-GnRH neuron adhesiveness is mostly mediated by SynCAM1 homophilic interactions. When erbB4 receptor function is disrupted in astrocytes, via transgenic expression of a dominant-negative erbB4 receptor form, SynCAM1-mediated adhesiveness is severely compromised. Conversely, SynCAM1 adhesive behavior is rapidly, but transiently, enhanced in astrocytes by ligand-dependent activation of erbB4 receptors, suggesting that erbB4-mediated events affecting SynCAM1 function contribute to regulate astrocyte adhesive communication.

The effect of glazing and aging on the surface properties of CAD/CAM resin blocks.

Science.gov (United States)

Tekçe, Neslihan; Fidan, Sinan; Tuncer, Safa; Kara, Dilan; Demirci, Mustafa

2018-02-01

To investigate the effect of accelerated aging on surface properties of glazed CAD/CAM resin blocks using a 2D surface profilometer and a 3D non-contact optical profilometer. Three types of CAD/CAM resin restorative materials, LAVA Ultimate (3M ESPE, St Paul, MN, USA), VITA Enamic (Vita Zahnfabrik H. Rauter, Bad Säckingen, Germany), and Cerasmart (GC Corparation, Tokyo, Japan) were used for this study. CAD/CAM blocks were cut in 3-mm thickness slabs and divided into three groups; Group 1: control group (specimens polished with 600 grit SCI paper); Group 2: specimens sandblasted, silanized, and glazed with Optiglaze Color (GC); Group 3: glazed specimens subjected to 5000 thermocycles (n=15). The surface roughness (R a and R z ) was evaluated using a profilometer and a 3D scanning instrument. Data were analyzed using two-way ANOVA and Tukey's post-hoc test ( P .05). For VITA and Cerasmart, the specimens in Group 1 exhibited significantly higher R a values than Group 2 ( P .05). Glaze material Optiglaze Color makes CAD/CAM resin surfaces smooth and glazed CAD/CAM surfaces seem resistant to deterioration under 5000 thermocycles.

Opening of material analysis beamline (BL-5) at NewSUBARU for industrial enterprises

International Nuclear Information System (INIS)

Hasegawa, Takayuki; Uemura, Masaharu; Tsurui, Takafumi; Shimizu, Masayoshi; Amemiya, Kenta; Fukushima, Sei; Ohta, Toshiaki; Motoyama, Muneyuki; Kanda, Kazuhiro

2010-01-01

A material analysis beamline for the industrial enterprises' use was completed at BL-5 of NewSUBARU synchrotron radiation facility in University of Hyogo in March 2008. BL-5 consists of two branch lines, one is a double crystal monochromator beamline (BL-5A) for the use in the higher-energy region (1300-4000 eV) and the other is a varied line spacing plane grating (VLSPG) monochromator beamline (BL-5B) for the use in the lower-energy region (50-1300 eV). These two branch lines can be operated simultaneously. BL-5 covers the soft X-ray region from 50 to 4000 eV and X-ray absorption spectrum can be measured with a high-energy resolution. The XAFS measurements in the total electron yield (TEY) and fluorescence yield (FLY) can be performed at BL-5A and BL-5B. In addition, the XPS spectra can be measured at BL-5B. BL-5 will be managed and maintained by the Synchrotron Analysis L.L.C. (SALLC), which is composed of the industrial companies, in cooperation with the staffs of the Laboratory of Advanced Science and Technology for Industry in University of Hyogo. Industrial users can be assisted by staffs of SALLC in the measurement at BL-5. (author)

Utilization of complementary and alternative medicine (CAM) among children from a German birth cohort (GINIplus): patterns, costs, and trends of use.

Science.gov (United States)

Italia, Salvatore; Brand, Helmut; Heinrich, Joachim; Berdel, Dietrich; von Berg, Andrea; Wolfenstetter, Silke Britta

2015-03-10

The use of complementary and alternative medicine (CAM) is widespread among children in Germany and other European countries. Only a few studies are available on trends in pediatric CAM use over time. The study's objective was to present updated results for prevalence, predictors, and costs of CAM use among German children and a comparison with findings from a previous follow-up of the same birth cohort. Data were collected for 3013 children on their utilization of medicinal products (during the last 4 weeks) and consultation with CAM providers (in the preceding year) from a German birth cohort study (GINIplus, 15-year follow-up) using a self-administered questionnaire. The reported medicinal CAMs were classified into six categories (homeopathy, herbal drugs, nutritionals, minerals and trace elements, microorganisms, further CAM). Drug prices were traced using pharmaceutical identification numbers (PZNs), or otherwise conservatively estimated. Finally, the results were compared with data obtained from the 10-year follow-up of the same birth cohort study by adopting the identical methodology. In all, 26% of the reported 2489 drugs were medicinal CAM. The 4-week prevalence for homeopathy and herbal drug use was 7.5% and 5.6%, respectively. Some 13.9% of the children used at least one type of medicinal CAM in the preceding 4 weeks. The 1-year prevalence for consultation with CAM providers was 10.8%. From the drugs identified as CAM, 53.7% were homeopathic remedies, and 30.8% were herbal drugs. Factors associated with higher medicinal CAM use were female gender, residing in Munich, and higher maternal education. A homeopathy user utilized on average homeopathic remedies worth EUR 15.28. The corresponding figure for herbal drug users was EUR 16.02, and EUR 18.72 for overall medicinal CAM users. Compared with the 10-year follow-up, the prevalence of homeopathy use was more than halved (-52%) and dropped substantially for herbal drug use (-36%) and overall CAM use (-38

Content-addressable read/write memories for image analysis

Science.gov (United States)

Snyder, W. E.; Savage, C. D.

1982-01-01

The commonly encountered image analysis problems of region labeling and clustering are found to be cases of search-and-rename problem which can be solved in parallel by a system architecture that is inherently suitable for VLSI implementation. This architecture is a novel form of content-addressable memory (CAM) which provides parallel search and update functions, allowing speed reductions down to constant time per operation. It has been proposed in related investigations by Hall (1981) that, with VLSI, CAM-based structures with enhanced instruction sets for general purpose processing will be feasible.

Developmental distribution of CaM kinase II in the antennal lobe of the sphinx moth Manduca sexta.

Science.gov (United States)

Lohr, Christian; Bergstein, Sandra; Hirnet, Daniela

2007-01-01

The antennal lobe (primary olfactory center of insects) is completely reorganized during metamorphosis. This reorganization is accompanied by changing patterns of calcium signaling in neurons and glial cells. In the present study, we investigated the developmental distribution of a major calcium-dependent protein, viz., calcium/calmodulin-dependent protein kinase II (CaM kinase II), in the antennal lobe of the sphinx moth Manduca sexta by using a monoclonal antibody. During synaptogenesis (developmental stages 6-10), we found a redistribution of CaM kinase II immunoreactivity, from a homogeneous distribution in the immature neuropil to an accumulation in the neuropil of the glomeruli. CaM kinase II immunoreactivity was less intense in olfactory receptor axons of the antennal nerve and antennal lobe glial cells. Western blot analysis revealed a growing content of CaM kinase II in antennal lobe tissue throughout metamorphosis. Injection of the CaM kinase inhibitor KN-93 into pupae resulted in a reduced number of antennal lobe glial cells migrating into the neuropil to form borders around glomeruli. The results suggest that CaM kinase II is involved in glial cell migration.

Concurrent Complementary and Alternative Medicine CAM and Conventional Rehabilitation Therapy in the Management of Children with Developmental Disorders

Directory of Open Access Journals (Sweden)

Soo Yeon Kim

2013-01-01

Full Text Available Background. We investigated the concurrent use of conventional rehabilitations and complementary and alternative medicine (CAM therapies for the long-term management of children with developmental disorders (DDs. Methods. The parents or caregivers of 533 children with DDs (age range, 1–19 years who visited the rehabilitation centers were surveyed using in depth face-to-face interviews. Results. Of the 533 patients enrolled, 520 completed the questionnaire (97% response rate. A total of 292 (56% children were receiving multiple therapies, more than two conventional rehabilitations and CAM, at the time of the interview. A total of 249 (48% children reported lifetime CAM use, 23% used CAM at the time of the interview, and 62% of the patients planned to use CAM therapy in the future. Conventional rehabilitation therapies used at the time of the interview included physical therapy (30%, speech therapy (28%, and occupational therapy (19%, and the CAM therapies included herbal medicine (5% and acupuncture or moxibustion (3%. The respondents indicated that in the future they planned to use acupuncture or moxibustion (57%, occupational therapy (18%, cognitive behavioral therapy (16%, speech therapy (10%, and physical therapy (8%. Conclusion. Concurrent management as conventional rehabilitations and CAM therapies is widely used by children with DDs.

Adherence of Candida to complete denture surfaces in vitro: A comparison of conventional and CAD/CAM complete dentures.

Science.gov (United States)

Al-Fouzan, Afnan F; Al-Mejrad, Lamya A; Albarrag, Ahmed M

2017-10-01

The goal of this study was to compare the adhesion of Candida albicans to the surfaces of CAD/CAM and conventionally fabricated complete denture bases. Twenty discs of acrylic resin poly (methyl methacrylate) were fabricated with CAD/CAM and conventional procedures (heat-polymerized acrylic resin). The specimens were divided into two groups: 10 discs were fabricated using the CAD/CAM procedure (Wieland Digital Denture Ivoclar Vivadent), and 10 discs were fabricated using a conventional flasking and pressure-pack technique. Candida colonization was performed on all the specimens using four Candida albicans isolates. The difference in Candida albicans adhesion on the discs was evaluated. The number of adherent yeast cells was calculated by the colony-forming units (CFU) and by Fluorescence microscopy. There was a significant difference in the adhesion of Candida albicans to the complete denture bases created with CAD/CAM and the adhesion to those created with the conventional procedure. The CAD/CAM denture bases exhibited less adhesion of Candida albicans than did the denture bases created with the conventional procedure ( P CAD/CAM procedure for fabricating complete dentures showed promising potential for reducing the adherence of Candida to the denture base surface. Clinical Implications. Complete dentures made with the CAD/CAM procedure might decrease the incidence of denture stomatitis compared with conventional dentures.

A scoping review of research on complementary and alternative medicine (CAM) and the mass media: looking back, moving forward.

Science.gov (United States)

Weeks, Laura C; Strudsholm, Tina

2008-07-19

The use of complementary and alternative medicine (CAM) has become more common in Western developed countries in recent years, as has media reporting on CAM and related issues. Correspondingly, media reports are a primary information source regarding decisions to use CAM. Research on CAM related media reports is becoming increasingly relevant and important; however, identifying key concepts to guide future research is problematic due to the dispersed nature of completed research in this field. A scoping review was conducted to: 1) determine the amount, focus and nature of research on CAM and the mass media; and 2) summarize and disseminate related research results. The main phases were: 1) searching for relevant studies; 2) selecting studies based on pre-defined inclusion criteria; 3) extracting data; and 4) collating, summarizing and reporting the results. Of 4,454 studies identified through various search strategies, 16 were relevant to our objectives and included in a final sample. CAM and media research has focused primarily on print media coverage of a range of CAM therapies, although only a few studies articulated differences within the range of therapies surveyed. Research has been developed through a variety of disciplinary perspectives, with a focus on representation research. The research reviewed suggests that journalists draw on a range of sources to prepare media reports, although most commonly they cite conventional (versus CAM) sources and personal anecdotes. The tone of media reports appears generally positive, which may be related to a lack of reporting on issues related to risk and safety. Finally, a variety of discourses within media representations of CAM are apparent that each appeal to a specific audience through resonance with their specific concerns. Research on CAM and the mass media spans multiple disciplines and strategies of inquiry; however, despite the diversity in approach, it is clear that issues related to production and reception

Motion laws synthesis for cam mechanisms with multiple follower displacement

Science.gov (United States)

Podgornyj, Yu I.; Skeeba, V. Yu; Kirillov, A. V.; Martynova, T. G.; Skeeba, P. Yu

2018-03-01

The research discusses the cam mechanisms design. The analysis of specialized literature indicates that the synthesis of the cam mechanisms laws of motion is currently done mainly by a standard set of acceleration curves. In some cases, the designer needs to synthesize a new acceleration law which should be task-specific and enforce a certain production step. The values of the technological loads and inertia forces loads generated by the mechanism are calculated to analyze the slay mechanism behavior in the production of closely woven fabrics. Mathematical packages MathCad and SolidWorks are used in calculations. As a result of the research, the authors propose the methodology for synthesizing the slay mechanism with multiple follower displacements for the point of contact between the reed and the fabric edge. Theoretical studies have been tested on a specific machine model (STB loom). The authors have synthesized the motion law of the filling threads beat-up mechanism for the production of strong fabrics. New basic and closing cam profiles are proposed. The results are designed to enhance the possibilities of the looms and to recommend the most efficient equipment operation modes for the producers.

The varied contribution of significant others to Complementary and Alternative Medicine (CAM) uptake by men with cancer: a qualitative analysis.

Science.gov (United States)

Klafke, Nadja; Eliott, Jaklin A; Olver, Ian N; Wittert, Gary A

2014-06-01

To explore how men's Significant Others (SOs), including family members and close friends, contribute to the uptake and maintenance of specific CAM therapies. This study was the second, qualitative phase of a mixed-methods project investigating the use of CAM in an Australian male cancer population. Male participants were purposefully selected from a pool of 403 patients who answered a survey in the first quantitative phase (94% response rate and 86% consent rate for follow-up interview). Then semi-structured interviews among 26 men with a variety of cancers and 24 SOs were conducted. All 43 interviews were recorded, transcribed, and analysed thematically. Men used CAM/Natural products to cope with physical concerns, and this was actively supported by men's SOs who contributed to the uptake and maintenance of these CAMs. The shared CAM preparation and consumption functioned to strengthen the bond between men and their SOs, and also helped men's SOs to cope with uncertainty and regain control. In contrast, men practiced CAM/Mind-body medicine to receive emotional benefits, and only rarely shared this practice with their SOs, indicating a need for coping with emotions in a private way. Men's CAM use is a multifaceted process that can be better understood by considering CAM categories separately. CAM/Natural products help men to cope with physical concerns, while CAM/Mind-body medicine assist men to cope with their emotions in a private way. Oncology professionals can use this information to better promote and implement integrative cancer care services. Copyright © 2014 Elsevier Ltd. All rights reserved.

Motorized CPM/CAM physiotherapy device with sliding-mode Fuzzy Neural Network control loop.

Science.gov (United States)

Ho, Hung-Jung; Chen, Tien-Chi

2009-11-01

Continuous passive motion (CPM) and controllable active motion (CAM) physiotherapy devices promote rehabilitation of damaged joints. This paper presents a computerized CPM/CAM system that obviates the need for mechanical resistance devices such as springs. The system is controlled by a computer which performs sliding-mode Fuzzy Neural Network (FNN) calculations online. CAM-type resistance force is generated by the active performance of an electric motor which is controlled so as to oppose the motion of the patient's leg. A force sensor under the patient's foot on the device pedal provides data for feedback in a sliding-mode FNN control loop built around the motor. Via an active impedance control feedback system, the controller drives the motor to behave similarly to a damped spring by generating and controlling the amplitude and direction of the pedal force in relation to the patient's leg. Experiments demonstrate the high sensitivity and speed of the device. The PC-based feedback nature of the control loop means that sophisticated auto-adaptable CPM/CAM custom-designed physiotherapy becomes possible. The computer base also allows extensive data recording, data analysis and network-connected remote patient monitoring.

CAD-CAM plates versus conventional fixation plates for primary mandibular reconstruction: A biomechanical in vitro analysis.

Science.gov (United States)

Rendenbach, Carsten; Sellenschloh, Kay; Gerbig, Lucca; Morlock, Michael M; Beck-Broichsitter, Benedicta; Smeets, Ralf; Heiland, Max; Huber, Gerd; Hanken, Henning

2017-11-01

CAD/CAM reconstruction plates have become a viable option for mandible reconstruction. The aim of this study was to determine whether CAD/CAM plates provide higher fatigue strength compared with conventional fixation systems. 1.0 mm miniplates, 2.0 mm conventional locking plates (DePuy Synthes, Umkirch, Germany), and 2.0 mm CAD/CAM plates (Materialise, Leuven, Belgium/DePuy Synthes) were used to reconstruct a polyurethane mandible model (Synbone, Malans, CH) with cortical and cancellous bone equivalents. Mastication was simulated via cyclic dynamic testing using a universal testing machine (MTS, Bionix, Eden Prairie, MN, USA) until material failure reached a rate of 1 Hz with increasing loads on the left side. No significant difference was found between the groups until a load of 300 N. At higher loads, vertical displacement differed increasingly, with a poorer performance of miniplates (p = 0.04). Plate breakage occurred in miniplates and conventional locking plates. Screw breakage was recorded as the primary failure mechanism in CAD/CAM plates. Stiffness was significantly higher with the CAD/CAM plates (p = 0.04). CAD/CAM plates and reconstruction plates provide higher fatigue strength than miniplates, and stiffness is highest in CAD/CAM systems. All tested fixation methods seem sufficiently stable for mandible reconstruction. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Assessment of reliability of CAD-CAM tooth-colored implant custom abutments.

Science.gov (United States)

Guilherme, Nuno Marques; Chung, Kwok-Hung; Flinn, Brian D; Zheng, Cheng; Raigrodski, Ariel J

2016-08-01

Information is lacking about the fatigue resistance of computer-aided design and computer-aided manufacturing (CAD-CAM) tooth-colored implant custom abutment materials. The purpose of this in vitro study was to investigate the reliability of different types of CAD-CAM tooth-colored implant custom abutments. Zirconia (Lava Plus), lithium disilicate (IPS e.max CAD), and resin-based composite (Lava Ultimate) abutments were fabricated using CAD-CAM technology and bonded to machined titanium-6 aluminum-4 vanadium (Ti-6Al-4V) alloy inserts for conical connection implants (NobelReplace Conical Connection RP 4.3×10 mm; Nobel Biocare). Three groups (n=19) were assessed: group ZR, CAD-CAM zirconia/Ti-6Al-4V bonded abutments; group RC, CAD-CAM resin-based composite/Ti-6Al-4V bonded abutments; and group LD, CAD-CAM lithium disilicate/Ti-6Al-4V bonded abutments. Fifty-seven implant abutments were secured to implants and embedded in autopolymerizing acrylic resin according to ISO standard 14801. Static failure load (n=5) and fatigue failure load (n=14) were tested. Weibull cumulative damage analysis was used to calculate step-stress reliability at 150-N and 200-N loads with 2-sided 90% confidence limits. Representative fractured specimens were examined using stereomicroscopy and scanning electron microscopy to observe fracture patterns. Weibull plots revealed β values of 2.59 for group ZR, 0.30 for group RC, and 0.58 for group LD, indicating a wear-out or cumulative fatigue pattern for group ZR and load as the failure accelerating factor for groups RC and LD. Fractographic observation disclosed that failures initiated in the interproximal area where the lingual tensile stresses meet the compressive facial stresses for the early failure specimens. Plastic deformation of titanium inserts with fracture was observed for zirconia abutments in fatigue resistance testing. Significantly higher reliability was found in group ZR, and no significant differences in reliability were

The prevalence of cam-type deformity of the hip joint: a survey of 4151 subjects of the Copenhagen Osteoarthritis Study

DEFF Research Database (Denmark)

Gosvig, K.K.; Jacobsen, S.; Sonne-Holm, S.

2008-01-01

. The relationships between cam malformation and self-reported hip pain were evaluated, and the relative importance of known risk factors for cam malformation estimated. RESULTS: We found a pronounced sex-related difference in cam-deformity distribution. The overall prevalence of cam deformity was approximately 17......BACKGROUND: Cam deformity is a preosteoarthritic malformation causing premature hip-joint degeneration. While the pathogenetic pathway from deformity to osteoarthrosis (OA) has been well established, almost nothing is known of the malformation's epidemiology. PURPOSE: To determine the distribution......% in men and 4% in women. The distribution of cam deformity was unaltered in subjects with normal joint-space width or other features of hip-joint degeneration. We found no significant association with self-reported hip pain, nor did we find any relative importance of possible risk factors for hip...

Anti-L1CAM radioimmunotherapy is more effective with the radiolanthanide terbium-161 compared to lutetium-177 in an ovarian cancer model

International Nuclear Information System (INIS)

Gruenberg, Juergen; Lindenblatt, Dennis; Cohrs, Susan; Fischer, Eliane; Dorrer, Holger; Zhernosekov, Konstantin; Koester, Ulli; Tuerler, Andreas; Schibli, Roger

2014-01-01

The L1 cell adhesion molecule (L1CAM) is considered a valuable target for therapeutic intervention in different types of cancer. Recent studies have shown that anti-L1CAM radioimmunotherapy (RIT) with 67 Cu- and 177 Lu-labelled internalising monoclonal antibody (mAb) chCE7 was effective in the treatment of human ovarian cancer xenografts. In this study, we directly compared the therapeutic efficacy of anti-L1CAM RIT against human ovarian cancer under equitoxic conditions with the radiolanthanide 177 Lu and the potential alternative 161 Tb in an ovarian cancer therapy model. Tb was produced by neutron bombardment of enriched 160 Gd targets. 161 Tb and 177 Lu were used for radiolabelling of DOTA-conjugated antibodies. The in vivo behaviour of the radioimmunoconjugates (RICs) was assessed in IGROV1 tumour-bearing nude mice using biodistribution experiments and SPECT/CT imaging. After ascertaining the maximal tolerated doses (MTD) the therapeutic impact of 50 % MTD of 177 Lu- and 161 Tb-DOTA-chCE7 was evaluated in groups of ten mice by monitoring the tumour size of subcutaneous IGROV1 tumours. The average number of DOTA ligands per antibody was 2.5 and maximum specific activities of 600 MBq/mg were achieved under identical radiolabelling conditions. RICs were stable in human plasma for at least 48 h. 177 Lu- and 161 Tb-DOTA-chCE7 showed high tumour uptake (37.8-39.0 %IA/g, 144 h p.i.) with low levels in off-target organs. SPECT/CT images confirmed the biodistribution data. 161 Tb-labelled chCE7 revealed a higher radiotoxicity in nude mice (MTD: 10 MBq) than the 177 Lu-labelled counterpart (MTD: 12 MBq). In a comparative therapy study with equitoxic doses, tumour growth inhibition was better by 82.6 % for the 161 Tb-DOTA-chCE7 than the 177 Lu-DOTA-chCE7 RIT. Our study is the first to show that anti-L1CAM 161 Tb RIT is more effective compared to 177 Lu RIT in ovarian cancer xenografts. These results suggest that 161 Tb is a promising candidate for future clinical

TurtleCam: A “Smart” Autonomous Underwater Vehicle for Investigating Behaviors and Habitats of Sea Turtles

Directory of Open Access Journals (Sweden)

Kara L. Dodge

2018-03-01

Full Text Available Sea turtles inhabiting coastal environments routinely encounter anthropogenic hazards, including fisheries, vessel traffic, pollution, dredging, and drilling. To support mitigation of potential threats, it is important to understand fine-scale sea turtle behaviors in a variety of habitats. Recent advancements in autonomous underwater vehicles (AUVs now make it possible to directly observe and study the subsurface behaviors and habitats of marine megafauna, including sea turtles. Here, we describe a “smart” AUV capability developed to study free-swimming marine animals, and demonstrate the utility of this technology in a pilot study investigating the behaviors and habitat of leatherback turtles (Dermochelys coriacea. We used a Remote Environmental Monitoring UnitS (REMUS-100 AUV, designated “TurtleCam,” that was modified to locate, follow and film tagged turtles for up to 8 h while simultaneously collecting environmental data. The TurtleCam system consists of a 100-m depth rated vehicle outfitted with a circular Ultra-Short BaseLine receiver array for omni-directional tracking of a tagged animal via a custom transponder tag that we attached to the turtle with two suction cups. The AUV collects video with six high-definition cameras (five mounted in the vehicle nose and one mounted aft and we added a camera to the animal-borne transponder tag to record behavior from the turtle's perspective. Since behavior is likely a response to habitat factors, we collected concurrent in situ oceanographic data (bathymetry, temperature, salinity, chlorophyll-a, turbidity, currents along the turtle's track. We tested the TurtleCam system during 2016 and 2017 in a densely populated coastal region off Cape Cod, Massachusetts, USA, where foraging leatherbacks overlap with fixed fishing gear and concentrated commercial and recreational vessel traffic. Here we present example data from one leatherback turtle to demonstrate the utility of TurtleCam. The

Mid-IR Imaging of Orion BN/KL: Modeling of Physical Conditions and Energy Balance

Science.gov (United States)

Gezari, Daniel; Varosi, Frank; Dwek, Eli; Danchi, William C.; Tan, Jonathan; Okumura, Shin-ichiro

2016-01-01

We have modeled two mid-infrared imaging photometry data sets to determine the spatial distribution of physical conditions in the BN/KL (Becklin-Neugebauer / Kleinmann-Low) infrared complex. We observed the BN/KL region using the 10-meter Keck I telescope and the LWS (Living With a Star) in the direct imaging mode, over a 13 inch by 19 inch field . We also modeled images obtained with COMICS (Cooled Mid-Infrared Camera and Spectrometer, Kataza et al. 2000) at the 8.2-meter SUBARU telescope, over a total field of view [which] is 31 inches by 41 inches in a total of nine bands: 7.8, 8.8, 9.7, 10.5, 11.7, 12.4, 18.5, 20.8 and 24.8 microns with 1-micron bandwidth interference filters.

Surface and top-of-atmosphere radiative feedback kernels for CESM-CAM5

Science.gov (United States)

Pendergrass, Angeline G.; Conley, Andrew; Vitt, Francis M.

2018-02-01

Radiative kernels at the top of the atmosphere are useful for decomposing changes in atmospheric radiative fluxes due to feedbacks from atmosphere and surface temperature, water vapor, and surface albedo. Here we describe and validate radiative kernels calculated with the large-ensemble version of CAM5, CESM1.1.2, at the top of the atmosphere and the surface. Estimates of the radiative forcing from greenhouse gases and aerosols in RCP8.5 in the CESM large-ensemble simulations are also diagnosed. As an application, feedbacks are calculated for the CESM large ensemble. The kernels are freely available at https://doi.org/10.5065/D6F47MT6" target="_blank">https://doi.org/10.5065/D6F47MT6, and accompanying software can be downloaded from https://github.com/apendergrass/cam5-kernels" target="_blank">https://github.com/apendergrass/cam5-kernels.

Laser-Induced Fluorescence Emission (L.I.F.E.): searching for Mars organics with a UV-enhanced PanCam.

Science.gov (United States)

Storrie-Lombardi, Michael C; Muller, Jan-Peter; Fisk, Martin R; Cousins, Claire; Sattler, Birgit; Griffiths, Andrew D; Coates, Andrew J

2009-12-01

The European Space Agency will launch the ExoMars mission in 2016 with a primary goal of surveying the martian subsurface for evidence of organic material. We have recently investigated the utility of including either a 365 nm light-emitting diode or a 375 nm laser light source in the ExoMars rover panoramic camera (PanCam). Such a modification would make it feasible to monitor rover drill cuttings optically for the fluorescence signatures of aromatic organic molecules and map the distribution of polycyclic aromatic hydrocarbons (PAHs) as a function of depth to the 2 m limit of the ExoMars drill. The technique described requires no sample preparation, does not consume irreplaceable resources, and would allow mission control to prioritize deployment of organic detection experiments that require sample destruction, expenditure of non-replaceable consumables, or both. We report here for the first time laser-induced fluorescence emission (L.I.F.E.) imaging detection limits for anthracene, pyrene, and perylene targets doped onto a Mars analog granular peridotite with a 375 nm Nichia laser diode in optically uncorrected wide-angle mode. Data were collected via the Beagle 2 PanCam backup filter wheel fitted with original blue (440 nm), green (530 nm), and red (670 nm) filters. All three PAH species can be detected with the PanCam green (530 nm) filter. Detection limits in the green band for signal-to-noise ratios (S/N) > 10 are 49 parts per million (ppm) for anthracene, 145 ppm for pyrene, and 20 ppm for perylene. The anthracene detection limit improves to 7 ppm with use of the PanCam blue filter. We discuss soil-dependent detection limit constraints; use of UV excitation with other rover cameras, which provides higher spatial resolution; and the advantages of focused and wide-angle laser modes. Finally, we discuss application of L.I.F.E. techniques at multiple wavelengths for exploration of Mars analog extreme environments on Earth, including Icelandic hydrothermally

Immunohistochemical expression of epithelial cell adhesion molecule (EpCAM) in mucoepidermoid carcinoma compared to normal salivary gland tissues.

Science.gov (United States)

Kamal, Noura M; Salem, Hend M; Dahmoush, Heba M

2017-07-01

Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor which displays biological, histological and clinical diversity thus representing a challenge for its diagnosis and management. Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein identified as a tumor specific antigen due to its frequent overexpression in the majority of epithelial carcinomas and its correlation with prognosis. It is considered to be a promising biomarker used as a therapeutic target already in ongoing clinical trials. The purpose of this study was to investigate the pattern, cellular characterization and level of EpCAM expression in MEC and demonstrate its correlation with histologic grading which may benefit future clinical trials using EpCAM targeted therapy. 48 specimens (12 normal salivary gland tissue and 36 MEC) were collected and EpCAM membranous expression was evaluated by immunohistochemistry. Total immunoscore (TIS) was evaluated, the term 'EpCAM overexpression' was given for tissues showing a total immunoscore >4. A highly significant difference was observed between TIS percent values in control and different grades of MEC (p<0.001). High grade MEC (HG-MEC) was the highest EpCAM expressor. In addition, EpCAM expression pattern differed among the different grades. EpCAM expression was detected in MEC, and its overexpression correlated with increasing the histological grade. The diffuse membranous expression in HG-MEC could be of diagnostic value in relation to the patchy expression observed in both low grade and intermediate grade MEC. Copyright © 2017 Elsevier Ltd. All rights reserved.

Optical properties of CAD-CAM ceramic systems.

Science.gov (United States)

Della Bona, Alvaro; Nogueira, Audrea D; Pecho, Oscar E

2014-09-01

To evaluate the direct transmittance (T%), translucency, opacity and opalescence of CAD-CAM ceramic systems and the correlation between the translucency parameter (TP) and the contrast ratio (CR). Specimens of shades A1, A2 and A3 (n=5) were fabricated from CAD-CAM ceramic blocks (IPS e.max(®) CAD HT and LT, IPS Empress(®) CAD HT and LT, Paradigm™ C, and VITABLOCS(®) Mark II) and polished to 1.0±0.01mm in thickness. A spectrophotometer (Lambda 20) was used to measure T% on the wavelength range of 400-780nm. Another spectrophotometer (VITA Easyshade(®) Advance) was used to measure the CIE L(*)a(*)b(*) coordinates and the reflectance value (Y) of samples on white and black backgrounds. TP, CR and the opalescence parameter (OP) were calculated. Data were statistically analysed using VAF (variance accounting for) coefficient with Cauchy-Schwarz inequality, one-way ANOVA, Tukey's test, Bonferroni correction and Pearson's correlation. T% of some ceramic systems is dependent on the wavelength. The spectral behaviour showed a slight and constant increase in T% up to approximately 550nm, then some ceramics changed the behaviour as the wavelength gets longer. TP and CR values ranged, respectively, from 16.79 to 21.69 and from 0.52 to 0.64 (r(2)=-0.97). OP values ranged from 3.01 to 7.64. The microstructure of CAD-CAM ceramic systems influenced the optical properties. TP and CR showed a strong correlation for all ceramic systems evaluated. Yet, all ceramics showed some degree of light transmittance. In addition to shade, this study showed that other optical properties influence on the natural appearance of dental ceramics. Copyright © 2014 Elsevier Ltd. All rights reserved.

Cyp1a-dependent activation of xenobiotics in endothelial linings of the chorioallantoic membrane (CAM) in birds

Energy Technology Data Exchange (ETDEWEB)

Annas, A.; Brittebo, E.B. [Uppsala Univ. (Sweden). Dept. of Toxicology; Brunstroem, B. [Dept. of Environmental Toxicology, Uppsala Univ., Uppsala (Sweden)

2000-08-01

Metabolic activation of the heterocyclic amine 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) and 7-ethoxyresorufin O-deethylase (EROD) activity were examined in the chorioallantoic membrane (CAM) of 15-day-old chicken and 18-day-old eider duck embryos. The embryos were pretreated with an Ah receptor agonist, i.e. {beta}-naphthoflavone (BNF) or 3,3',4,4',5-pentachlorobiphenyl (PCB 126), or vehicle in ovo. BNF and PCB 126 induced EROD activity and covalent binding of [{sup 3}H]Trp-P-1 seven- to tenfold in the CAM of chicken embryos. In the CAM of eider duck embryos, which are known to be nonresponsive to coplanar PCBs, PCB 126 treatment had no effect on EROD activity or covalent binding of [{sup 3}H]Trp-P-1 whereas BNF treatment increased these activities five- and threefold, respectively. Light microscopic autoradiography was used to identify the cellular localization of covalent binding of [{sup 3}H]Trp-P-1 in the CAM. Preferential binding was observed in endothelial cells in intraepithelial capillaries in the chorionic epithelium and in blood vessels in the mesenchymal layer. The addition of the CYP1A inhibitor ellipticine abolished the covalent binding of [{sup 3}H]Trp-P-1 in the CAM of BNF- and PCB 126-treated chicken and eider duck embryos. The results suggest that CYP1A-dependent metabolic activity can be induced in blood vessel endothelia in the CAM of bird embryos following exposure to Ah receptor agonists and that the CAM may be a target tissue for CYP1A-activated environmental pollutants. Furthermore, the highly vascularized CAM could be used as a model for studies of Ah receptor-mediated alterations in the vasculature. (orig.)

Cyp1a-dependent activation of xenobiotics in endothelial linings of the chorioallantoic membrane (CAM) in birds

International Nuclear Information System (INIS)

Annas, A.; Brittebo, E.B.

2000-01-01

Metabolic activation of the heterocyclic amine 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) and 7-ethoxyresorufin O-deethylase (EROD) activity were examined in the chorioallantoic membrane (CAM) of 15-day-old chicken and 18-day-old eider duck embryos. The embryos were pretreated with an Ah receptor agonist, i.e. β-naphthoflavone (BNF) or 3,3',4,4',5-pentachlorobiphenyl (PCB 126), or vehicle in ovo. BNF and PCB 126 induced EROD activity and covalent binding of [ 3 H]Trp-P-1 seven- to tenfold in the CAM of chicken embryos. In the CAM of eider duck embryos, which are known to be nonresponsive to coplanar PCBs, PCB 126 treatment had no effect on EROD activity or covalent binding of [ 3 H]Trp-P-1 whereas BNF treatment increased these activities five- and threefold, respectively. Light microscopic autoradiography was used to identify the cellular localization of covalent binding of [ 3 H]Trp-P-1 in the CAM. Preferential binding was observed in endothelial cells in intraepithelial capillaries in the chorionic epithelium and in blood vessels in the mesenchymal layer. The addition of the CYP1A inhibitor ellipticine abolished the covalent binding of [ 3 H]Trp-P-1 in the CAM of BNF- and PCB 126-treated chicken and eider duck embryos. The results suggest that CYP1A-dependent metabolic activity can be induced in blood vessel endothelia in the CAM of bird embryos following exposure to Ah receptor agonists and that the CAM may be a target tissue for CYP1A-activated environmental pollutants. Furthermore, the highly vascularized CAM could be used as a model for studies of Ah receptor-mediated alterations in the vasculature. (orig.)

Comparison of Fit of Dentures Fabricated by Traditional Techniques Versus CAD/CAM Technology.

Science.gov (United States)

McLaughlin, J Bryan; Ramos, Van; Dickinson, Douglas P

2017-11-14

To compare the shrinkage of denture bases fabricated by three methods: CAD/CAM, compression molding, and injection molding. The effect of arch form and palate depth was also tested. Nine titanium casts, representing combinations of tapered, ovoid, and square arch forms and shallow, medium, and deep palate depths, were fabricated using electron beam melting (EBM) technology. For each base fabrication method, three poly(vinyl siloxane) impressions were made from each cast, 27 dentures for each method. Compression-molded dentures were fabricated using Lucitone 199 poly methyl methacrylate (PMMA), and injection molded dentures with Ivobase's Hybrid Pink PMMA. For CAD/CAM, denture bases were designed and milled by Avadent using their Light PMMA. To quantify the space between the denture and the master cast, silicone duplicating material was placed in the intaglio of the dentures, the titanium master cast was seated under pressure, and the silicone was then trimmed and recovered. Three silicone measurements per denture were recorded, for a total of 243 measurements. Each silicone measurement was weighed and adjusted to the surface area of the respective arch, giving an average and standard deviation for each denture. Comparison of manufacturing methods showed a statistically significant difference (p = 0.0001). Using a ratio of the means, compression molding had on average 41% to 47% more space than injection molding and CAD/CAM. Comparison of arch/palate forms showed a statistically significant difference (p = 0.023), with shallow palate forms having more space with compression molding. The ovoid shallow form showed CAD/CAM and compression molding had more space than injection molding. Overall, injection molding and CAD/CAM fabrication methods produced equally well-fitting dentures, with both having a better fit than compression molding. Shallow palates appear to be more affected by shrinkage than medium or deep palates. Shallow ovoid arch forms appear to benefit from

CAMS newly detected meteor showers and the sporadic background

Science.gov (United States)

Jenniskens, P.; Nénon, Q.; Gural, P. S.; Albers, J.; Haberman, B.; Johnson, B.; Morales, R.; Grigsby, B. J.; Samuels, D.; Johannink, C.

2016-03-01

The Cameras for Allsky Meteor Surveillance (CAMS) video-based meteoroid orbit survey adds 60 newly identified showers to the IAU Working List of Meteor Showers (numbers 427, 445-446, 506-507, and part of 643-750). 28 of these are also detected in the independent SonotaCo survey. In total, 230 meteor showers and shower components are identified in CAMS data, 177 of which are detected in at least two independent surveys. From the power-law size frequency distribution of detected showers, we extrapolate that 36% of all CAMS-observed meteors originated from ∼700 showers above the N = 1 per 110,000 shower limit. 71% of mass falling to Earth from streams arrives on Jupiter-family type orbits. The transient Geminids account for another 15%. All meteoroids not assigned to streams form a sporadic background with highest detected numbers from the apex source, but with 98% of mass falling in from the antihelion source. Even at large ∼7-mm sizes, a Poynting-Robertson drag evolved population is detected, which implies that the Grün et al. collisional lifetimes at these sizes are underestimated by about a factor of 10. While these large grains survive collisions, many fade on a 104-y timescale, possibly because they disintegrate into smaller particles by processes other than collisions, leaving a more resilient population to evolve.

Survey on the use of CAD-CAM technology by UK and Irish dental technicians.

Science.gov (United States)

Blackwell, E; Nesbit, M; Petridis, H

2017-05-12

Statement of the problem Digital workflows (CAD/CAM) have been introduced in dentistry during recent years. No published information exists on dental technicians' use and reporting of this technology.Purpose The aim of this cross sectional survey was to identify the extent digital technology has infiltrated the workplace and to investigate the factors affecting the use of CAD-CAM technology by dental laboratory technicians within Ireland and the UK.Materials and methods A web-based questionnaire was composed (Opinio, Object Planet Inc. Oslo, Norway) and distributed to UK and Irish dental technicians. Answers to all questions were anonymous and grouped such that general information was gathered initially, followed by branching of the survey into two sections depending on whether or not the respondent worked with CAD-CAM technology. Results were compiled and statistical analysis (Fisher's Exact test, SPSS, IBM, Armonk, New York, USA) was performed in order to investigate any correlation between various demographic variables and the answers provided.Results The survey was distributed to 760 UK technicians and 77 Irish technicians. The total number of completed surveys was 105, which yielded a total response rate of 14%. Most technicians reported using some form of CAD/CAM aspect in the workflow, and this was more significant for technicians working in large laboratories. Most training received was company-led. Large laboratories were also significantly correlated with less outsourcing of CAD/CAM work and a change in dental material use leading to the increase of zirconia and the decrease of noble alloys. Dental technicians did not report any significant change in working relationships and staffing as a result of CAD/CAM incorporation. High initial investment cost was the most common reason quoted from non-users, along with the lack of such technology in their working environment.

The role of complementary and alternative medicine (CAM) routines and rituals in men with cancer and their significant others (SOs): a qualitative investigation.

Science.gov (United States)

Klafke, Nadja; Eliott, Jaklin A; Olver, Ian N; Wittert, Gary A

2014-05-01

Complementary and alternative medicine (CAM) is frequently used in cancer patients, often with contribution of the significant others (SOs), but without consultation of healthcare professionals. This research explored how cancer patients integrate and maintain CAM use in their everyday life, and how SOs are involved in it. In this qualitative study, male participants were selected from a preceding Australian survey on CAM use in men with cancer (94 % response rate and 86 % consent rate for follow-up interview). Semistructured interviews were conducted with 26 men and 24 SOs until data saturation was reached. Interview transcripts were coded and analyzed thematically, thereby paying close attention to participants' language in use. A major theme associated with high CAM use was "CAM routines and rituals," as it was identified that men with cancer practiced CAM as (1) functional routines, (2) meaningful rituals, and (3) mental/spiritual routines or/and rituals. Regular CAM use was associated with intrapersonal and interpersonal benefits: CAM routines provided men with certainty and control, and CAM rituals functioned for cancer patients and their SOs as a means to create meaning, thereby working to counter fear and uncertainty consequent upon a diagnosis of cancer. SOs contributed most to men's uptake and maintenance of dietary-based CAM in ritualistic form resulting in interpersonal bonding and enhanced closeness. CAM routines and rituals constitute key elements in cancer patients' regular and satisfied CAM use, and they promote familial strengthening. Clinicians and physicians can convey these benefits to patient consultations, further promoting the safe and effective use of CAM.

Unique CAD/CAM three-quarter crown restoration of a central incisor: a case report.

Science.gov (United States)

Goldberg, Marvin B; Siegel, Sharon C; Rezakani, Niloufar

2013-07-01

Computer-aided design and computer-aided manufacturing (CAD/CAM) dentistry has been in use for more than 2 decades. Recent improvements in this technology have made CAD/CAM restorations a viable alternative for routine dental care. This technology is being taught in dental schools to prepare students for contemporary dental practice and is particularly useful in unique restorative situations that allow conservation of tooth structure. This case report describes the restoration of a central incisor that was previously restored with an unesthetic three-quarter gold crown. The tooth exhibited recurrent caries and an unaffected labial wall of supported enamel. A CAD/CAM three-quarter crown was planned to conserve tooth structure. After preparation, the tooth was scanned for a CAD/CAM crown in order to fabricate a ceramic restoration, which was then milled and bonded, producing an esthetic result. Typically, in cases of esthetic enhancement, a labial laminate restoration is fabricated, but in this situation, a different approach was necessary to make a design for the lingual surface of an anterior tooth.

“We make choices we think are going to save us”: Debate and stance identification for online breast cancer CAM discussions

Science.gov (United States)

Zhang, Shaodian; Qiu, Lin; Chen, Frank; Zhang, Weinan; Yu, Yong; Elhadad, Noémie

2017-01-01

Patients discuss complementary and alternative medicine (CAM) in online health communities. Sometimes, patients’ conflicting opinions toward CAM-related issues trigger debates in the community. The objectives of this paper are to identify such debates, identify controversial CAM therapies in a popular online breast cancer community, as well as patients’ stances towards them. To scale our analysis, we trained a set of classifiers. We first constructed a supervised classifier based on a long short-term memory neural network (LSTM) stacked over a convolutional neural network (CNN) to detect automatically CAM-related debates from a popular breast cancer forum. Members’ stances in these debates were also identified by a CNN-based classifier. Finally, posts automatically flagged as debates by the classifier were analyzed to explore which specific CAM therapies trigger debates more often than others. Our methods are able to detect CAM debates with F score of 77%, and identify stances with F score of 70%. The debate classifier identified about 1/6 of all CAM-related posts as debate. About 60% of CAM-related debate posts represent the supportive stance toward CAM usage. Qualitative analysis shows that some specific therapies, such as Gerson therapy and usage of laetrile, trigger debates frequently among members of the breast cancer community. This study demonstrates that neural networks can effectively locate debates on usage and effectiveness of controversial CAM therapies, and can help make sense of patients’ opinions on such issues under dispute. As to CAM for breast cancer, perceptions of their effectiveness vary among patients. Many of the specific therapies trigger debates frequently and are worth more exploration in future work. PMID:28967000

Influence of different surface treatments on bond strength of novel CAD/CAM restorative materials to resin cement.

Science.gov (United States)

Kömürcüoğlu, Meltem Bektaş; Sağırkaya, Elçin; Tulga, Ayça

2017-12-01

To evaluate the effects of different surface treatments on the bond strength of novel CAD/CAM restorative materials to resin cement by four point bending test. The CAD/CAM materials under investigation were e.max CAD, Mark II, Lava Ultimate, and Enamic. A total of 400 bar specimens (4×1.2×12 mm) (n=10) milled from the CAD/CAM blocks underwent various pretreatments (no pretreatment (C), hydrofluoric acid (A), hydrofluoric acid + universal adhesive (Scotchbond) (AS), sandblasting (Sb), and sandblasting + universal adhesive (SbS)). The bars were luted end-to-end on the prepared surfaces with a dual curing adhesive resin cement (Variolink N, Ivoclar Vivadent) on the custom-made stainless steel mold. Ten test specimens for each treatment and material combination were performed with four point bending test method. Data were analyzed using ANOVA and Tukey's test. The surface treatment and type of CAD/CAM restorative material showed a significant effect on the four point bending strength (FPBS) ( P CAD/CAM restorative materials was modified after treatments. The surface treatment of sandblasting or HF acid etching in combination with a universal adhesive containing MDP can be suggested for the adhesive cementation of the novel CAD/CAM restorative materials.

Use of selected complementary and alternative medicine (CAM) treatments in veterans with cancer or chronic pain: a cross-sectional survey

OpenAIRE

McEachrane-Gross, F Patricia; Liebschutz, Jane M; Berlowitz, Dan

2006-01-01

Abstract Background Complementary and alternative medicine (CAM) is emerging as an important form of care in the United States. We sought to measure the prevalence of selected CAM use among veterans attending oncology and chronic pain clinics and to describe the characteristics of CAM use in this population. Methods The self-administered, mail-in survey included questions on demographics, health beliefs, medical problems and 6 common CAM treatments (herbs, dietary supplements, chiropractic ca...

Overexpression of HepaCAM inhibits cell viability and motility through suppressing nucleus translocation of androgen receptor and ERK signaling in prostate cancer.

Science.gov (United States)

Song, Xuedong; Wang, Yin; Du, Hongfei; Fan, Yanru; Yang, Xue; Wang, Xiaorong; Wu, Xiaohou; Luo, Chunli

2014-07-01

HepaCAM is suppressed in a variety of human cancers, and involved in cell adhesion, growth, migration, invasion, and survival. However, the expression and function of HepaCAM in prostate cancer are still unknown. HepaCAM expression has been detected by RT-PCR, Western blotting and immunohistochemistry staining in prostate cell lines RWPE-1, LNCap, DU145, PC3, and in 75 human prostate tissue specimens, respectively. Meanwhile, the cell proliferation ability was detected by WST-8 assay. The role of HepaCAM in prostate cancer cell migration and invasion was examined by wound healing and transwell assay. And flow cytometry was used to observe the apoptosis of prostate cancer cells. Then we detected changes of Androgen Receptor translocation and ERK signaling using immunofluorescence staining and western blot after overexpression of HepaCAM. The HepaCAM expression was significantly down-regulated in prostate cancer tissues and undetected in prostate cancer cells. However, the low HepaCAM expression was not statistically associated with clinicopathological characteristics of prostate cancer. Overexpression of HepaCAM in prostate cancer cells decreased the cell proliferation, migration and invasion, and induced the cell apoptosis. Meanwhile, HepaCAM prevented the androgen receptor translocation from the cytoplasm to the nucleus and down-regulated the MAPK/ERK signaling. Our results suggested that HepaCAM acted as a tumor suppressor in prostate cancer. HepaCAM inhibited cell viability and motility which might be through suppressing the nuclear translocation of Androgen Receptor and down-regulating the ERK signaling. Therefore, it was indicated that HepaCAM may be a potential therapeutic target for prostate cancer. © 2014 Wiley Periodicals, Inc.