Physical protection equipment study. Final report

International Nuclear Information System (INIS)

Haberman, W.

1977-06-01

This report summarizes the work performed by MITRE for the U.S. Nuclear Regulatory Commission. The major products of this effort are a Catalog of Physical Protection Equipment, a Guide for Evaluation of Physical Protection Equipment, a book of Reference Materials, and a set of guidelines for use in the development of a methodology for measuring levels of security system effectiveness. A summary of recommendations resulting from this study is also presented

Environmental Regulation and Food Safety: Studies of Protection ...

International Development Research Centre (IDRC) Digital Library (Canada)

Environmental Regulation and Food Safety: Studies of Protection and Protectionism. Book cover Environmental Regulation and Food Safety: Studies of Protection and Protectionism. Directeur(s) : Veena Jha. Maison(s) d'édition : Edward Elgar, IDRC. 1 janvier 2006. ISBN : 184542512X. 250 pages. e-ISBN : 155250185X.

Economic optimization of natural hazard protection - conceptual study of existing approaches

Science.gov (United States)

Spackova, Olga; Straub, Daniel

2013-04-01

Risk-based planning of protection measures against natural hazards has become a common practice in many countries. The selection procedure aims at identifying an economically efficient strategy with regard to the estimated costs and risk (i.e. expected damage). A correct setting of the evaluation methodology and decision criteria should ensure an optimal selection of the portfolio of risk protection measures under a limited state budget. To demonstrate the efficiency of investments, indicators such as Benefit-Cost Ratio (BCR), Marginal Costs (MC) or Net Present Value (NPV) are commonly used. However, the methodologies for efficiency evaluation differ amongst different countries and different hazard types (floods, earthquakes etc.). Additionally, several inconsistencies can be found in the applications of the indicators in practice. This is likely to lead to a suboptimal selection of the protection strategies. This study provides a general formulation for optimization of the natural hazard protection measures from a socio-economic perspective. It assumes that all costs and risks can be expressed in monetary values. The study regards the problem as a discrete hierarchical optimization, where the state level sets the criteria and constraints, while the actual optimization is made on the regional level (towns, catchments) when designing particular protection measures and selecting the optimal protection level. The study shows that in case of an unlimited budget, the task is quite trivial, as it is sufficient to optimize the protection measures in individual regions independently (by minimizing the sum of risk and cost). However, if the budget is limited, the need for an optimal allocation of resources amongst the regions arises. To ensure this, minimum values of BCR or MC can be required by the state, which must be achieved in each region. The study investigates the meaning of these indicators in the optimization task at the conceptual level and compares their

Studies on optimization of radiation protection for patients in diagnostic radiology

International Nuclear Information System (INIS)

Wei, Z.; Zhang, Q.; Li, W.; Li, K.; Wei, L.; Zong, X.; Qiang, Z.; Wu, Y.

1994-01-01

For the exposure of patients in diagnostic radiology, individual dose limit does not apply, but optimization of radiological protection may play a major role. This project has been carried out with the purpose of improving the protection of patients in medical diagnostic radiology in China utilizing the principles of optimization. Taking Sichuan, Shandong and Beijing as surveyed areas, we investigated the present situation of the protection of patients. In the survey, the patient doses were classified into practical dose, justified dose and optimized dose to evaluate the influences of managerial and equipment factors separately. The results show that there are some urgent protection problems in X-ray protection to be solved in the surveyed regions. This paper, however, points out that the prospects of reducing patient doses are encouraging provided that appropriate measures are adopted. For instance, taking proper managerial measures without radical change of existing equipments may reduce patient doses in chest fluoroscopy and radiography by 40% and 18% respectively; refitting some equipment may reduce the doses by 82.4% in chest fluoroscopy, 66% in chest radiography, and 80% in barium meal examination of the gastrointestinal (GI) tract. Using chest radiography instead of fluoroscopy supplemented by other protection measures may reduce the doses by 91.7%. Optimization analysis shows that adoption of the above measures conforms to the principle of optimization of radiation protection. (authors). 5 refs., 7 tabs

Radiation protection research and studies after the Chernobyl accident

International Nuclear Information System (INIS)

Madelmont, C.; Coulon, R.; Legrand, B.; Manesse, D.; Rzepka, J.P.

1989-04-01

The effects on the environment of the Chernobyl Power Plant accident, which happened in the reactors unit 4, are analyzed. The aim of the study is to show the main fields of research and development to be considered, in order to improve the knowledge on public or local radiation protection. The following aspects of the problem are discussed: the long range atmospheric transfer, the environment monitoring, the problems related to the food chain transfers, the environment recovery and the estimation of the sanitary effects. The Chernobyl disaster confirms: the priority of special plans of action to protect the surrounding population; that the special plans of action must be followed by after-disaster actions, which take into account methods for the environment recovery; that the conventional systematic approach can not be satisfactorily applied to manage such a critical situation, and a new one must be developed. Moreover, the identification of the most exposed (population) groups, far from the nearby affected area, are to be considered [fr

Protective effects of a zinc-hydroxyapatite toothpaste on enamel erosion: SEM study.

Science.gov (United States)

Colombo, Marco; Beltrami, Riccardo; Rattalino, Davide; Mirando, Maria; Chiesa, Marco; Poggio, Claudio

2016-01-01

The aim of the present in vitro study was to evaluate the protective effects of a zinc-hydroxyapatite toothpaste against an erosive challenge produced by a soft drink (Coca-Cola) using Scanning Electron Microscopy (SEM). Forty specimens were assigned to 4 groups of 10 specimens each (group 1: no erosive challenge, no toothpaste treatment, group 2: erosive challenge, no toothpaste treatment, group 3: erosive challenge, fluoride toothpaste treatment, group 4: erosive challenge, zinc-hydroxyapatite toothpaste treatment). The surface of each specimen was imaged by SEM. A visual rating system was used to evaluate the condition of the enamel surface; results were analyzed by nonparametric statistical methods. Statistically significant differences were found between the samples untreated and those immersed in Coca-Cola (group 1, 2); the highest grade of damage was found in group 2, while the lowest grade was recorded in the samples of group 4. Comparing the groups, the two analyzed toothpaste tended to protect in different extend. In this study treatment of erosively challenged enamel with Zn-Hap toothpaste showed a clear protective effect. This was greater than the effect observed for a normal fluoride toothpaste and confirmed the potential benefit the Zn-HAP technology can provide in protecting enamel from erosive acid challenges.

Pressure and protective factors influencing nursing students' self-esteem: A content analysis study.

Science.gov (United States)

Valizadeh, Leila; Zamanzadeh, Vahid; Gargari, Rahim Badri; Ghahramanian, Akram; Tabrizi, Faranak Jabbarzadeh; Keogh, Brian

2016-01-01

A review of the literature shows that the range of self-esteem in nursing students ranges from normal to low. It is hypothesized that different contextual factors could affect levels of self-esteem. The main aim of this study was to explore these factors from the viewpoint of Iranian nursing students using a qualitative approach. A qualitative content analysis study. Faculty of Nursing and Midwifery, 2014. Fourteen student nurses and two qualified nurses. This study has been applied to various depths of interpretation. Semi-structured interviews were used to collect the data. Fourteen student nurses and two qualified nurses were interviewed. Two main themes of the "pressure factors" with subthemes: low self-efficacy, sense of triviality, ineffective instructor-student interaction, low self-confidence and "protective factors" with subthemes: knowledge acquisition, mirror of valuability, professional autonomy, religious beliefs, and choosing the nursing field with interest was extracted in this study. Results showed that these themes have interaction with each other like a seesaw, as pressure factors decrease, the effect of protective factors on the self-esteem are increased. Nurse educators not only should try to improve the students' skills and knowledge, but should also try to enhance the protective factors and decrease pressure factors by enhancing the nursing students' feeling of being important, using participatory teaching methods, considering students' feedback, and attempting to improve facilities at the clinics are also recommended. Copyright © 2015. Published by Elsevier Ltd.

Reactivity of Monolayer Protected Silver Clusters Towards Excess Ligand: A Calorimetric Study

KAUST Repository

Baksi, Ananya

2017-10-31

Reactivity of monolayer protected atomically precise clusters of noble metals is of significant research interest. Till date very few experimental data are available on the reaction thermodynamics of such clusters. Here we report a calorimetric study of the reaction of glutathione (GSH) protected silver clusters in presence of excess ligand, GSH using isothermal titration calorimetry (ITC). We have studied Ag11(SG)7 and Ag32(SG)19 clusters and compared their reactivity with GSH protected silver nanoparticles (AgNPs) and silver ions. Clusters show intermediate reactivity towards excess ligand com-pared to nanoparticles and silver ions. Several control experiments were performed to understand the degradation mech-anism of these silver clusters and nanoparticles. Effect of dissolved oxygen in the degradation process was studied in de-tail and found that it did not have a significant role, although alternate pathways of degradation with the involvement of oxygen cannot be ruled out. Direct confirmation of the fact that functionalized metal clusters fall in-between NPs and atomic systems in their stability is obtained experimentally for the first time. Several other thermophysical parameters of these clusters were also determined including, density, speed of sound, isentropic compressibility and coefficient of thermal expansion.

The IAA Cosmic Study 'Protecting the Environment of Celestial Bodies'

Science.gov (United States)

Rettberg, Petra; Hofmann, Mahulena; Williamson, Mark

The study group tasked with producing this International Academy of Astronautics (IAA) `Cosmic Study' on Protecting the Environment of Celestial Bodies was formed under the aus-pices of IAA Commission V (Space Policy, Law Economy). The members of the international, multidisciplinary team assembled to undertake the Study accept, as a premise, the Planetary Protection Policy guidelines developed by COSPAR, which differentiate the degree of protec-tion according to the type of space activity and the celestial body under investigation (such that fly-by missions have less stringent requirements than lander missions, while Mars is `better protected' than the Moon). However, this Study goes deliberately beyond the interpretation of `Planetary Protection' as a set of methods for protecting the planets from biological con-tamination and extends consideration to the geophysical, industrial and cultural realms. The Study concludes that, from the perspective of current and future activities in outer space, present measures aimed at protecting the space environment are insufficient. Deficiencies in-clude a lack of suitable in-situ methods of chemical and biological detection and the absence of a systematic record of radioactive contaminants. Other issues identified by the Study include an insufficient legal framework, a shortage of effective economic tools and a lack of political will to address these concerns. It is expected that new detection methods under development, and the resultant increase in microbiological knowledge of the planetary surfaces, will lead to changes in the COSPAR planetary protection guidelines and bioburden limits. It is important, however, that any new approaches should not hamper future exploration and exploitation of celestial bodies more than absolutely necessary. The Study addresses the need to find a balance between protection and freedom of action. From a legal perspective, the Study concludes that a general consensus on protection of the

Study of Determinants of Lung Cancer Protective Behaviors in Esfahan Steel Company Workers Based On Protection Motivation Theory

OpenAIRE

mohammadali Morowatisharifabad; Leila Hadi varnamkhavasti; Mohammadjavad Zare; Hossein Fallahzadeh; zohre Karimiankakolaki

2017-01-01

Introduction: Lung cancer is known the leading cause of death among cancers. Since in our country a comprehensive scientific information not available on the determinants of protective behavior of lung cancer among workers, this study, aimed to examine determinants of lung cancer protective behaviors among Esfahan Steel Company (ESCO) workers based on protection motivation theory. Methods: This cross-sectional study was performed on 253 workers of the ESCO who were randomly selected. In th...

Experimental study on short-circuit characteristics of the new protection circuit of insulated gate bipolar transistor

International Nuclear Information System (INIS)

Ji, In-Hwan; Choi, Young-Hwan; Ha, Min-Woo; Han, Min-Koo; Choi, Yearn-Ik

2006-01-01

A new protection circuit employing the collector to emitter voltage (V CE ) sensing scheme for short-circuit withstanding capability of the insulated gate bipolar transistor (IGBT) is proposed and verified by experimental results. Because the current path between the gate and collector can be successfully eliminated in the proposed protection circuit, the power consumption can be reduced and the gate input impedance can be increased. Previous study is limited to dc characteristics. However, experimental results show that the proposed protection circuit successfully reduces the over-current of main IGBT by 80.4% under the short-circuit condition

Army Study Shows Decline In Behavioral Health Stigma

Science.gov (United States)

2012-01-01

Army Study Shows Decline in Behavioral Health Stigma By Rob McIlvaine Army News Service WASHINGTON, Jan. 20, 2012 - A newly released Army study on...conference yesterday. The three-year study outlines the problem of suicide in the Army and related issues of substance abuse, spouse abuse and child abuse...REPORT TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Army Study Shows Decline In Behavioral Health Stigma 5a. CONTRACT

Experimental study of the Rapsodie protections; Etude experimentale des protections de rapsodie

Energy Technology Data Exchange (ETDEWEB)

Chapelet, M; Edeline, J; Lhiaubet, G [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

1968-07-01

This report gives details of the protection tests which have been carried out by the Protection Sub-Commission during the starting-up trials on the reactor Rapsodie. The main types of tests reported concern the flux measurements in the core, the reflectors, the sodium and the near biological protections, the radio-protection measurements in the premises, and the activation of the principal fluids. In the last part, the results obtained are analyzed and compared to the forecast calculations. (author) [French] Ce rapport rend compte des essais de protection qui ont ete effectues dans le cadre des essais de demarrage de RAPSODIE par la Sous Commission Protection. Les principaux types d'essais rapportes sont les mesures de flux dans le coeur, les reflecteurs, le sodium et les protections biologiques proches, les mesures de radioprotection dans les locaux, et l'activation des principaux fluides. Dans la derniere partie, les resultats obtenus sont analyses et compares aux calculs previsionnels. (auteur)

Protection of surface states in topological nanoparticles

Science.gov (United States)

Siroki, Gleb; Haynes, Peter D.; Lee, Derek K. K.; Giannini, Vincenzo

2017-07-01

Topological insulators host protected electronic states at their surface. These states show little sensitivity to disorder. For miniaturization one wants to exploit their robustness at the smallest sizes possible. This is also beneficial for optical applications and catalysis, which favor large surface-to-volume ratios. However, it is not known whether discrete states in particles share the protection of their continuous counterparts in large crystals. Here we study the protection of the states hosted by topological insulator nanoparticles. Using both analytical and tight-binding simulations, we show that the states benefit from the same level of protection as those on a planar surface. The results hold for many shapes and sustain surface roughness which may be useful in photonics, spectroscopy, and chemistry. They complement past studies of large crystals—at the other end of possible length scales. The protection of the nanoparticles suggests that samples of all intermediate sizes also possess protected states.

Radiation protection in an interventional laboratory: a comparative study of Australian and Saudi Arabian hospitals

International Nuclear Information System (INIS)

Alahmari, Mohammed Ali S.; Sun, Zhonghua; Bartlett, Andrew

2016-01-01

This study aimed to investigate whether the use of protection devices and attitudes of interventional professionals (including radiologists, cardiologists, vascular surgeons, medical imaging technicians and nurses) towards radiation protection will differ between Saudi Arabian and Australian hospitals. Hard copies of an anonymous survey were distributed to 10 and 6 clinical departments in the Eastern province of Saudi Arabia and metropolitan hospitals in Western Australia, respectively. The overall response rate was 43 % comprising 110 Australian participants and 63 % comprising 147 Saudi participants. Analysis showed that Australian respondents differed significantly from Saudi respondents with respect to their usages of leaded glasses (p < 0.001), ceiling-suspended lead screen (p < 0.001) and lead drape suspended from the table (p < 0.001). This study indicates that the trained interventional professionals in Australia tend to adhere to benefit from having an array of tools for personal radiation protection than the corresponding group in Saudi Arabia. (authors)

Physical protection

International Nuclear Information System (INIS)

Myers, D.A.

1989-01-01

Physical protection is defined and its function in relation to other functions of a State System of Accounting for and Control of Nuclear Materials is described. The need for a uniform minimum international standard for physical protection as well as the need for international cooperation in physical protection is emphasized. The IAEA's INFCIRC/225/Rev. 1 (Annex 1) is reviewed. The Convention on the Physical Protection of Nuclear Material (Annex 2) is discussed. Photographs show examples of typical physical protection technology (Annex 3)

Determinants of inadequate parental sun protection behaviour in their children--results of a cross-sectional study in Germany.

Science.gov (United States)

Klostermann, Swaantje; Bolte, Gabriele

2014-03-01

Unprotected sun exposure especially during childhood is a risk factor for skin cancer. A combined use of sun protection measures is recommended to protect children. However, the prevalence and determinants for combined use have been scarcely studied in children. The objective of this study was to identify determinants of parental sun protection behaviour. A cross-sectional survey was performed in five regions in Bavaria (Germany) during school entrance health examination (2010/2011). Parents of 4579 children (47% female, aged 5-6 years) completed a self-administered questionnaire (response 61%). Most children were regularly protected with single measures (shade (69%), clothes (80%), hat (83%), sunscreen (89%), sunglasses (20%)). However, regarding regular and combined use, >50% of children were inadequately protected. Larger family size, lower household equivalent income, darker skin and sunburn history were associated with inadequate use of different sun protection measures. The less frequent use of one sun protection measure was associated with less frequent use of the others. Child's sex, migration background, parental education and sun exposure showed inconsistent results regarding the different sun protection outcomes. Based on our results a regular, combined and correct use of multiple sun protection for children should be promoted independent of sociodemographic characteristics. Priority of shade, clothes and hat before sunscreen should be clarified. Copyright © 2013 Elsevier GmbH. All rights reserved.

Demographic Differences in Sun Protection Beliefs and Behavior: A Community-Based Study in Shanghai, China

Science.gov (United States)

Yan, Shuxian; Xu, Feng; Yang, Chunxue; Li, Fei; Fan, Jing; Wang, Linggao; Cai, Minqiang; Zhu, Jianfeng; Kan, Haidong; Xu, Jinhua

2015-01-01

Objective: We want to know the attitudes and behaviors towards UV protection and we want to analyze the difference between different Chinese demographic groups in this study. Methods: A community-based study was undertaken in Shanghai from October 2009 to January 2010. The participants, ages 20–60 years old, were screened by cluster sampling and were investigated through interviews at their own homes. Personal basic information and questions pertaining to their knowledge and attitudes towards sunlight and sun protective activities were included in the questionnaire. Results: We completed 5964 questionnaires (2794 men and 3170 women). Eighty-six percent of the respondents belonged to Fitzpatrick skin type IV. Knowledge about UV-induced risks was known by more than half of the participants. However, only one-third of the participants thought they needed sun protection in winter and indoors or in vehicles, and 27% of the participants acknowledged tanning was not favorable. The attitudes towards sun exposure varied greatly, showing significant differences based on gender, age, socioeconomic groups and skin type groups (p sun-protective behaviors than males and those of an older age and lower education level (p sun protection existing in our surveyed Chinese population, especially in males and lower socioeconomic population, which could allow for planning prevention campaigns and exploring sun-preventive products. PMID:25794187

Study of axial protections of unloading machines of graphite piles

International Nuclear Information System (INIS)

Duco, Jacques; Pepin, Pierre; Cabaret, Guy; Dubor, Monique

1969-10-01

As previous studies resulted in the development of a simple calculation formula based on experimental results for the calculation of neutron protection thicknesses for loading machines, this study aimed at determining axial protections of these machines which represent a specific problem: scattering of delayed neutrons in the machine inner cavity may result in an important neutron leakage through the upper part, at the level of the winch enclosure. In an experimental part, this study comprises the measurement of the neutron dose in a 2.60 m long and 54 cm diameter cylindrical cavity, and in the thickness of the surrounding concrete protection. In the second part, the authors present a calculation method which uses the Zeus and Mercure codes to interpret the results [fr

Protective Effect against Oxidative Stress in Medicinal Plant Extracts

International Nuclear Information System (INIS)

Kim, Jeong Hee; Lee, Eun Ju; Shin, Dong O; Hong, Sung Eun; Kim, Jin Kyu

2000-01-01

Protective effect of medicinal plant extracts against oxidative stress were screened in this study. Methanol extracts from 48 medicinal plants, which were reported to have antioxidative or anti-inflammatory effect were prepared and screened for their protective activity against chemically-induced and radiation-induced oxidative stress by using MTT assay. Thirty three samples showed protective activity against chemically-induced oxidative stress in various extent. Among those samples, extract of Glycyrrhiza uralensis revealed the strongest activity (25.9% at 100 μg/ml) with relatively lower cytotoxicity. Seven other samples showed higher than 20% protection at 100 μg/ml. These samples were tested for protection activity against radiation-induced oxidative stress. Methanol extract of Alpina officinarum showed the highest activity (17.8% at 20 μg/ml). Five fractions were prepared from the each 10 methanol extracts which showed high protective activity against oxidative stress. Among those fraction samples butanol fractions of Areca catechu var. dulcissima and Spirodela polyrrhiza showed the highest protective activities (78.8% and 77.2%, respectively, at 20 μg/ml)

Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) : an observational study

NARCIS (Netherlands)

Bingham, SA; Day, NE; Luben, R; Ferrari, P; Slimani, N; Norat, T; Clavel-Chapelon, F; Kesse, E; Boeing, H; Tjonneland, A; Overvad, K; Martinez, C; Dorronsoro, M; Gonzalez, CA; Key, TJ; Trichopoulou, A; Naska, A; Vineis, P; Tumino, R; Krogh, [No Value; Bueno-de-Mesquita, HB; Peeters, PHM; Berglund, G; Hallmans, G; Lund, E; Skeie, G; Kaaks, R; Riboli, E

2003-01-01

Background Dietary fibre is thought to protect against colorectal cancer but this view has been challenged by recent prospective and intervention studies that showed no protective effect. Methods We prospectively examined the association between dietary fibre intake and incidence of colorectal

Rabies immunosome (subunit vaccine) structure and immunogenicity. Pre- and post-exposure protection studies.

Science.gov (United States)

Perrin, P; Thibodeau, L; Sureau, P

1985-09-01

Rabies immunosomes (glycoprotein anchored on pre-formed liposomes) have been prepared in order to study their structural, biological and immunological properties. The glycoprotein molecules appear to have the same orientation on the immunosome as on the viral particle: (1) electron microscopy analysis shows particles of 40 to 70 nm with spikes protruding outward, (2) one particular epitope shows the same accessibility to a neutralizing monoclonal antibody as on the viral particle. When injected into animals, rabies immunosomes are cleared from the organism by a process different from that for the liposomes used to anchor the glycoprotein: a higher rate of transition through the spleen is observed with immunosomes than with purified glycoprotein or liposomes. Immunosomes induce high levels of neutralizing antibodies and protect animals against challenge with virulent strains. This protective activity is not altered after several months of storage at 4 degrees C. Furthermore, rabies immunosomes were shown to be efficient in post-exposure treatment of laboratory animals that had been experimentally infected with a lethal dose of a rabies wild strain.

Quench Detection and Magnet Protection Study for MFTF. LLL final review

International Nuclear Information System (INIS)

1979-06-01

The results of a Quench Detection and Magnet Protection Study for MFTF are summarized. The study was directed toward establishing requirements and guidelines for the electronic package used to protect the MFTF superconducting magnets. Two quench detection schemes were analyzed in detail, both of which require a programmable quench detector. Hardware and software recommendations for the quench detector were presented as well as criteria for dumping the magnet energy in the event of a quench. Overall magnet protection requirements were outlined in a detailed Failure Mode Effects and Criticality analysis, (FMECA). Hardware and software packages compatible with the FMECA were recommended, with the hardware consisting of flexible, dedicated intelligent modules specifically designed for magnet protection

More strictly protected areas are not necessarily more protective: evidence from Bolivia, Costa Rica, Indonesia, and Thailand

International Nuclear Information System (INIS)

Ferraro, Paul J; Hanauer, Merlin M; Miteva, Daniela A; Pattanayak, Subhrendu K; Canavire-Bacarreza, Gustavo Javier; Sims, Katharine R E

2013-01-01

National parks and other protected areas are at the forefront of global efforts to protect biodiversity and ecosystem services. However, not all protection is equal. Some areas are assigned strict legal protection that permits few extractive human uses. Other protected area designations permit a wider range of uses. Whether strictly protected areas are more effective in achieving environmental objectives is an empirical question: although strictly protected areas legally permit less anthropogenic disturbance, the social conflicts associated with assigning strict protection may lead politicians to assign strict protection to less-threatened areas and may lead citizens or enforcement agents to ignore the strict legal restrictions. We contrast the impacts of strictly and less strictly protected areas in four countries using IUCN designations to measure de jure strictness, data on deforestation to measure outcomes, and a quasi-experimental design to estimate impacts. On average, stricter protection reduced deforestation rates more than less strict protection, but the additional impact was not always large and sometimes arose because of where stricter protection was assigned rather than regulatory strictness per se. We also show that, in protected area studies contrasting y management regimes, there are y 2 policy-relevant impacts, rather than only y, as earlier studies have implied. (letter)

Ageing study of protection automation components of Olkiluoto nuclear power plant

International Nuclear Information System (INIS)

Simola, K.; Haenninen, S.

1993-07-01

A study on ageing of reactor protection system of the Olkiluoto nuclear power plant is described. The objective of the study was to present an ageing analysis approach and apply in to the automation chains of reactor protection system of the Olkiluoto nuclear power plant. The study includes the measuring instrumentation, the protection logics, and the control electronics of some pumps and valves. The analysis is based on the information collected on the structure of the system, environmental conditions and maintenance practices of components, and operating experience. Based on this information, the possible ageing effects of equipment and their safety significance are evaluated. (orig.). (15 refs., 16 figs., 12 tabs.)

The Saccharomyces boulardii CNCM I-745 Strain Shows Protective Effects against the B. anthracis LT Toxin

Directory of Open Access Journals (Sweden)

Rodolphe Pontier-Bres

2015-10-01

Full Text Available The probiotic yeast Saccharomyces boulardii (S. boulardii has been prescribed for the prophylaxis and treatment of several infectious diarrheal diseases. Gastrointestinal anthrax causes fatal systemic disease. In the present study, we investigated the protective effects conferred by Saccharomyces boulardii CNCM I-745 strain on polarized T84 columnar epithelial cells intoxicated by the lethal toxin (LT of Bacillus anthracis. Exposure of polarized T84 cells to LT affected cell monolayer integrity, modified the morphology of tight junctions and induced the formation of actin stress fibers. Overnight treatment of cells with S. boulardii before incubation with LT maintained the integrity of the monolayers, prevented morphological modification of tight junctions, restricted the effects of LT on actin remodeling and delayed LT-induced MEK-2 cleavage. Mechanistically, we demonstrated that in the presence of S. boulardii, the medium is depleted of both LF and PA sub-units of LT and the appearance of a cleaved form of PA. Our study highlights the potential of the S. boulardii CNCM I-745 strain as a prophylactic agent against the gastrointestinal form of anthrax.

The Saccharomyces boulardii CNCM I-745 strain shows protective effects against the B. anthracis LT toxin.

Science.gov (United States)

Pontier-Bres, Rodolphe; Rampal, Patrick; Peyron, Jean-François; Munro, Patrick; Lemichez, Emmanuel; Czerucka, Dorota

2015-10-30

The probiotic yeast Saccharomyces boulardii (S. boulardii) has been prescribed for the prophylaxis and treatment of several infectious diarrheal diseases. Gastrointestinal anthrax causes fatal systemic disease. In the present study, we investigated the protective effects conferred by Saccharomyces boulardii CNCM I-745 strain on polarized T84 columnar epithelial cells intoxicated by the lethal toxin (LT) of Bacillus anthracis. Exposure of polarized T84 cells to LT affected cell monolayer integrity, modified the morphology of tight junctions and induced the formation of actin stress fibers. Overnight treatment of cells with S. boulardii before incubation with LT maintained the integrity of the monolayers, prevented morphological modification of tight junctions, restricted the effects of LT on actin remodeling and delayed LT-induced MEK-2 cleavage. Mechanistically, we demonstrated that in the presence of S. boulardii, the medium is depleted of both LF and PA sub-units of LT and the appearance of a cleaved form of PA. Our study highlights the potential of the S. boulardii CNCM I-745 strain as a prophylactic agent against the gastrointestinal form of anthrax.

Electromagnetic computation methods for lightning surge protection studies

CERN Document Server

Baba, Yoshihiro

2016-01-01

This book is the first to consolidate current research and to examine the theories of electromagnetic computation methods in relation to lightning surge protection. The authors introduce and compare existing electromagnetic computation methods such as the method of moments (MOM), the partial element equivalent circuit (PEEC), the finite element method (FEM), the transmission-line modeling (TLM) method, and the finite-difference time-domain (FDTD) method. The application of FDTD method to lightning protection studies is a topic that has matured through many practical applications in the past decade, and the authors explain the derivation of Maxwell's equations required by the FDTD, and modeling of various electrical components needed in computing lightning electromagnetic fields and surges with the FDTD method. The book describes the application of FDTD method to current and emerging problems of lightning surge protection of continuously more complex installations, particularly in critical infrastructures of e...

The carrying capacity and the effects of protection level in three marine protected areas in the Balearic Islands (NW Mediterranean

Directory of Open Access Journals (Sweden)

Josep Coll

2012-08-01

Full Text Available The monitoring of fisheries target species in three marine protected areas (MPAs located in the NW Mediterranean provided important conclusions on management effects. The abundance, occurrence and biomass of large fish showed consistent and growing trends inside the MPAs. Fish diversity was also favoured by protection. Nevertheless, spatial variance of these indicators at a medium scale was often of the same order as that caused by time between different protection levels. The carrying capacity was determined for the first time in western Mediterranean MPAs in five out of six sites studied, and in all cases it was achieved within the first five years of protection. The observed values indicate that the system of the studied MPAs is representative of the general coastal environment of the Balearic Islands, but is far from the potential of other MPAs which are considered as hot spots in other localities. Likewise, this study shows that partially protected areas can also be fairly effective if their habitats fit with those required by target species and fishing modalities are suitably regulated or banned.

Factors Controlling Vegetation Fires in Protected and Non-Protected Areas of Myanmar

Science.gov (United States)

Biswas, Sumalika; Vadrevu, Krishna Prasad; Lwin, Zin Mar; Lasko, Kristofer; Justice, Christopher O.

2015-01-01

Fire is an important disturbance agent in Myanmar impacting several ecosystems. In this study, we quantify the factors impacting vegetation fires in protected and non-protected areas of Myanmar. Satellite datasets in conjunction with biophysical and anthropogenic factors were used in a spatial framework to map the causative factors of fires. Specifically, we used the frequency ratio method to assess the contribution of each causative factor to overall fire susceptibility at a 1km scale. Results suggested the mean fire density in non-protected areas was two times higher than the protected areas. Fire-land cover partition analysis suggested dominant fire occurrences in the savannas (protected areas) and woody savannas (non-protected areas). The five major fire causative factors in protected areas in descending order include population density, land cover, tree cover percent, travel time from nearest city and temperature. In contrast, the causative factors in non-protected areas were population density, tree cover percent, travel time from nearest city, temperature and elevation. The fire susceptibility analysis showed distinct spatial patterns with central Myanmar as a hot spot of vegetation fires. Results from propensity score matching suggested that forests within protected areas have 11% less fires than non-protected areas. Overall, our results identify important causative factors of fire useful to address broad scale fire risk concerns at a landscape scale in Myanmar. PMID:25909632

Factors controlling vegetation fires in protected and non-protected areas of myanmar.

Directory of Open Access Journals (Sweden)

Sumalika Biswas

Full Text Available Fire is an important disturbance agent in Myanmar impacting several ecosystems. In this study, we quantify the factors impacting vegetation fires in protected and non-protected areas of Myanmar. Satellite datasets in conjunction with biophysical and anthropogenic factors were used in a spatial framework to map the causative factors of fires. Specifically, we used the frequency ratio method to assess the contribution of each causative factor to overall fire susceptibility at a 1km scale. Results suggested the mean fire density in non-protected areas was two times higher than the protected areas. Fire-land cover partition analysis suggested dominant fire occurrences in the savannas (protected areas and woody savannas (non-protected areas. The five major fire causative factors in protected areas in descending order include population density, land cover, tree cover percent, travel time from nearest city and temperature. In contrast, the causative factors in non-protected areas were population density, tree cover percent, travel time from nearest city, temperature and elevation. The fire susceptibility analysis showed distinct spatial patterns with central Myanmar as a hot spot of vegetation fires. Results from propensity score matching suggested that forests within protected areas have 11% less fires than non-protected areas. Overall, our results identify important causative factors of fire useful to address broad scale fire risk concerns at a landscape scale in Myanmar.

Factors controlling vegetation fires in protected and non-protected areas of myanmar.

Science.gov (United States)

Biswas, Sumalika; Vadrevu, Krishna Prasad; Lwin, Zin Mar; Lasko, Kristofer; Justice, Christopher O

2015-01-01

Fire is an important disturbance agent in Myanmar impacting several ecosystems. In this study, we quantify the factors impacting vegetation fires in protected and non-protected areas of Myanmar. Satellite datasets in conjunction with biophysical and anthropogenic factors were used in a spatial framework to map the causative factors of fires. Specifically, we used the frequency ratio method to assess the contribution of each causative factor to overall fire susceptibility at a 1km scale. Results suggested the mean fire density in non-protected areas was two times higher than the protected areas. Fire-land cover partition analysis suggested dominant fire occurrences in the savannas (protected areas) and woody savannas (non-protected areas). The five major fire causative factors in protected areas in descending order include population density, land cover, tree cover percent, travel time from nearest city and temperature. In contrast, the causative factors in non-protected areas were population density, tree cover percent, travel time from nearest city, temperature and elevation. The fire susceptibility analysis showed distinct spatial patterns with central Myanmar as a hot spot of vegetation fires. Results from propensity score matching suggested that forests within protected areas have 11% less fires than non-protected areas. Overall, our results identify important causative factors of fire useful to address broad scale fire risk concerns at a landscape scale in Myanmar.

Protection Coordination in Electrical Substation Part-2 Unit Protections (Differential and Distance Protection)

OpenAIRE

TÜR, Mehmet Rida; Shobole, Abdulfetah; Baysal, Mustafa; Wadi, Mohammed

2018-01-01

Power systemsmust be protected against faults to ensure quality and reliable generation,transmission and distribution of power systems. Power system protection is providedby the protection relays. This paper is the second part of the ProtectionCoordination study for the Siddik Kardesler Substation. The protection fortransmission lines, transformer, bus bars and customer feeders is provided byovercurrent protection, differential and distance protection schemes. In thispaper, issues related wit...

Radiation protection in well logging: case studies in the Sudan

International Nuclear Information System (INIS)

Eltayeb, B. A.

2010-12-01

This study is performed to improve radiation protection level in well logging include tow case studies in Sudan (Lost or misplaced sources). General review of radiation and radiation protection basic concept is highlighted discussed. Also preview of well logging practice and source of radiation use in well logging, safety of radiation sources, storage and manage of not use sources (weak sources) and protection of worker and potential exposure for public and worker, investigations in cause of lost or misplaced sources in well. Assessment was made in well logging using checklist prepared in accordance with the International Atomic Energy Agency IAEA basic safety standard, International Committee for Radiological Protection ICRP and safety in transport of radiation sources. The checklist includes all requirement of radiation protection. It is found that all requirement was present except the delay of calibration of radiation detectors, the movement of radiation sources form storage to base of manipulated area need adequate care for shielding and safe transport and personal monitoring service must be provide in Sudan. Investigation was made in cause of lose of nine radiation source in well it is found that all those sources were loss in different depth in the well and with deferent location and there was no risk because there was no contamination of fluids which caused by damage of loss sources. Some recommendations were stated that, if implemented could improve the status of radiation protection in well logging. (Author)

Study of organic ablative thermal-protection coating for solid rocket motor

Science.gov (United States)

Hua, Zenggong

1992-06-01

A study is conducted to find a new interior thermal-protection material that possesses good thermal-protection performance and simple manufacturing possibilities. Quartz powder and Cr2O3 are investigated using epoxy resin as a binder and Al2O3 as the burning inhibitor. Results indicate that the developed thermal-protection coating is suitable as ablative insulation material for solid rocket motors.

Fire protection measures

International Nuclear Information System (INIS)

Bittner

1997-01-01

The presentation could only show a very brief overview of the analysis results of a wide study of the existing fire protection situation at Mochovce. As far not already done the next steps will be the selection of the final suppliers of the different measures, the detailed design and the implementation of the measures. As part of the further assistance in fire protection EUCOM will perform compliance checks of the DD and implementation and assist EMO for raising problems. Especially during the implementation of the measures the belonging quality checks have a high priority. Assuming that the implementation of measures will be in accordance with with the study results and the relevant basic design requirements it can be stated that safety level concerning fire protection will be in accordance with international requirement like IAEA 50 SG D2. The next step of our work will be the delta analysis for 2 unit and the relevant basic design as far as there are differences to unit 1. (author)

The usage of phase change materials in fire fighter protective clothing: its effect on thermal protection

Science.gov (United States)

Zhao, Mengmeng

2017-12-01

The thermal protective performance of the fire fighter protective clothing is of vital importance for fire fighters. In the study fabrics treated by phase change materials (PCMs) were applied in the multi-layered fabrics of the fire fighter protective clothing ensemble. The PCM fabrics were placed at the different layers of the clothing and their thermal protective performance were measured by a TPP tester. Results show that with the application of the PCM fabrics the thermal protection of the multi-layered fabrics was greatly increased. The time to reach a second degree burn was largely reduced. The location of the PCM fabrics at the different layers did not affect much on the thermal protective performance. The higher amount of the PCM adds on, the higher thermal protection was brought. The fabrics with PCMs of a higher melting temperature could contribute to higher thermal protection.

The primary study on protective effects of vallinin derivative on cell injury induced by radiation

International Nuclear Information System (INIS)

Zheng Hong; Wang Siying; Yan Yuqian; Wang Lin; Xu Qinzhi; Cong Jianbo; Zhou Pingkun

2008-01-01

In this paper, the protective effects of vallinin derivative VND3207 on cell injury induced by radiation were studied by the methods of methyl thiazolyl tetrazolium colorimetric assay (MTT) and electron spin resonance (ESR). At first, MTF method was used to evaluate the cytotoxicity of vallinin derivatives (VND3202-VND3209) in HFS cells. Then, MTT method was used to measure the proliferation activity of HeLa cells with 2 Gy irradiation treated with vallinin derivatives and measure the proliferation of AHH-1 cells treated with VND3207 before exposed to 4 Gy irradiation. And ESR detected the antioxidation activity of vallinin and VND3207. The results showed that VND3207 and VND3206 presented no toxin within 50 panol/L, and VND3207 and VND3209 had no proliferous effects on HeLa cells while VND3206 could expedite the tumor cell proliferation at 30 μmol/L, and by comrades VND3208 showed increased radiosensitivity of the HeLa cells. For the AHH1 cells exposed to 4 Gy irradiation, VND3207 presented the protective effects against radiation injury. ESR results also suggested that VND3207 could clean out free radicals. Its effect was far more potent than that of vanillin. From this study we primarily screened out the vallinin derivative VND3207 which has protective effects on cell injury induced by radiation and provided data for future research work. (authors)

Radiation protection study of radiology medical workers in radiodiagnosis area

International Nuclear Information System (INIS)

Gaona, E.; Canizal, C.; Garcia, M.A.; Orozco, M.; Rincon, A.; Padilla, Y.; Martinez, A.

1996-01-01

Aspects related to radiological safety and its organization in radiodiagnosis were evaluated by means of scanning carried out in 18 hospitals of Mexico City, divided in 11 public institutions and 7 private ones. The population being studied was: hospital personnel that works in radiodiagnosis. The survey was made with 31 dichotomic variables, being obtained 132 surveys. The personnel characteristics are 83% works in public institutions, 49% works in radiodiagnosis, 3% has an academic degree, 13% is member of a hospital professional association, 13% has updated information on radiological protection, 36% was trained, 45% works for more than 2 years, 52% uses personal dosemeter, less than the 20% knows about the fundamentals of the radiological protection and 24% states to suffer from biological radiation effects, due to the exposure to x-rays. As result of the study, it was found that the main problems that the radiological protection has, are: lack of training programs in radiological protection and supervision, medical surveillance and the few number of persons that takes part in clinical meetings and professional associations. (authors). 7 refs., 3 tabs

Xyloketal-derived small molecules show protective effect by decreasing mutant Huntingtin protein aggregates in Caenorhabditis elegans model of Huntington’s disease

Directory of Open Access Journals (Sweden)

Zeng YX

2016-04-01

Full Text Available Yixuan Zeng,1,2,* Wenyuan Guo,1,* Guangqing Xu,3 Qinmei Wang,4 Luyang Feng,1,2 Simei Long,1 Fengyin Liang,1 Yi Huang,1 Xilin Lu,1 Shichang Li,5 Jiebin Zhou,5 Jean-Marc Burgunder,6 Jiyan Pang,5 Zhong Pei1,2 1Department of Neurology, National Key Clinical Department and Key Discipline of Neurology, Guangdong Key Laboratory for Diagnosis and Treatment of Major Neurological Disease, The First Affiliated Hospital, Sun Yat-sen University, 2Guangzhou Center, Chinese Huntington’s Disease Network, 3Department of Rehabilitation, The First Affiliated Hospital, 4Key laboratory on Assisted Circulation, Ministry of Health, Department of Cardiovascular Medicine of the First Affiliated Hospital, 5School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China; 6Swiss Huntington’s Disease Center, Department of Neurology, University of Bern, Bern, Switzerland *These authors contributed equally to this work Abstract: Huntington’s disease is an autosomal-dominant neurodegenerative disorder, with chorea as the most prominent manifestation. The disease is caused by abnormal expansion of CAG codon repeats in the IT15 gene, which leads to the expression of a glutamine-rich protein named mutant Huntingtin (Htt. Because of its devastating disease burden and lack of valid treatment, development of more effective therapeutics for Huntington’s disease is urgently required. Xyloketal B, a natural product from mangrove fungus, has shown protective effects against toxicity in other neurodegenerative disease models such as Parkinson’s and Alzheimer’s diseases. To identify potential neuroprotective molecules for Huntington’s disease, six derivatives of xyloketal B were screened in a Caenorhabditis elegans Huntington’s disease model; all six compounds showed a protective effect. Molecular docking studies indicated that compound 1 could bind to residues GLN369 and GLN393 of the mutant Htt protein, forming a

Opportunism Motivation of Environmental Protection Activism and Corporate Governance: An Empirical Study from China

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Shengnan Li

2018-05-01

Full Text Available In the study of environmental protection issues for more than forty years, research on the impact of financial performance on environmental protection has been one of the important branches. In the framework of principal-agent theory, this paper explores the opportunism motives in a company’s environmental protection activism and the moderating role of corporate governance using the data of Chinese listed companies from 2005 to 2016. The study finds that: (1 the company’s environmental protection activism is driven by the opportunist motives of policymakers who want to mask their inability; and (2 environmental protection activism does not enhance the company’s future performance and value creation capability. Further studies find that corporate governance mechanisms play different moderating roles. Fund Shareholders play a positive governance role and reduce the correlation between financial performance and environmental protection activism. However, independence of the board of directors intensifies the opportunist motives. This paper provides new theoretical explanations for environmental protection decision-making, provides novel enlightenment for the protection of environmental protection policies in developing countries and regions.

Protective effect of atmospheric pressure plasma on oxidative stress-induced neuronal injuries: an in vitro study

International Nuclear Information System (INIS)

Yan, Xu; Jia, Mei; Li, Jiaxin; Yuan, Fang; Qiao, Yajun; Ouyang, Jiting

2017-01-01

Atmospheric pressure plasma jet (APPJ) can produce biological active species for biomedical applications. This work proves direct evidence of the protective effects of APPJ against oxidative stress. SH-SY5Y cells, a commonly used cell model for the study of neurotoxicity and neuroprotection, were treated with APPJ for different durations. Then, cells were exposed to 200 µ M H 2 O 2 for 24 h and cell viability was measured using a CCK-8 kit. Changes in cell apoptosis were further confirmed by calcein-AM fluorescence imaging and flow cytometry. Extracellular NO production was detected using the Griess method. The results showed that APPJ protected SH-SY5Y from H 2 O 2 -induced apoptosis in a time-dependent manner. Moreover, extracellular NO production was significantly increased with the APPJ treatment. The results show in vitro that APPJ treatment could protect SH-SY5Y cells from oxidative stress by reducing cell apoptosis, which might be related to the reactive nitrogen species induced by the APPJ treatment. Our results indicate that the APPJ may have therapeutic potential as a novel ‘NO donor drug’ in neuroprotection and in the treatment of neurodegenerative diseases. (paper)

Workstations studies and radiation protection; Etudes de postes et radioprotection

Energy Technology Data Exchange (ETDEWEB)

Lahaye, T. [Direction des relations du travail, 75 - Paris (France); Donadille, L.; Rehel, J.L.; Paquet, F. [Institut de Radioprotection et de Surete Nucleaire, 92 - Fontenay-aux-Roses (France); Beneli, C. [Paris-5 Univ., 75 (France); Cordoliani, Y.S. [Societe Francaise de Radioprotection, 92 - Fontenay-aux-Roses (France); Vrigneaud, J.M. [Assistance Publique - Hopitaux de Paris, 75 (France); Gauron, C. [Institut National de Recherche et de Securite, 75 - Paris (France); Petrequin, A.; Frison, D. [Association des Medecins du Travail des Salaries du Nucleaire (France); Jeannin, B. [Electricite de France (EDF), 75 - Paris (France); Charles, D. [Polinorsud (France); Carballeda, G. [cabinet Indigo Ergonomie, 33 - Merignac (France); Crouail, P. [Centre d' Etude sur l' Evaluation de la Protection dans le Domaine Nucleaire, 92 - Fontenay-aux-Roses (France); Valot, C. [IMASSA, 91 - Bretigny-sur-Orge (France)

2006-07-01

This day on the workstations studies for the workers follow-up, was organised by the research and health section. Devoted to the company doctors, for the competent persons in radiation protection, for the engineers of safety, it presented examples of methodologies and applications in the medical, industrial domain and the research, so contributing to a better understanding and an application of regulatory measures. The analysis of the workstation has to allow a reduction of the exposures and the risks and lead to the optimization of the medical follow-up. The agenda of this day included the different subjects as follow: evolution of the regulation in matter of demarcation of the regulated zones where the measures of workers protection are strengthened; presentation of the I.R.S.N. guide of help to the realization of a workstation study; implementation of a workstation study: case of radiology; the workstation studies in the research area; Is it necessary to impose the operational dosimetry in the services of radiodiagnostic? The experience feedback of a competent person in radiation protection (P.C.R.) in a hospital environment; radiation protection: elaboration of a good practices guide in medical field; the activities file in nuclear power plant: an evaluation tool of risks for the prevention. Methodological presentation and examples; insulated workstation study; the experience feedback of a provider; Contribution of the ergonomics to the determiners characterization in the ionizing radiation exposure situations;The workstations studies for the internal contamination in the fuel cycle facilities and the consideration of the results in the medical follow-up; R.E.L.I.R. necessity of workstation studies; the consideration of the human factor. (N.C.)

Radiation Protection, double-blind studies with radiopharmaceuticals

International Nuclear Information System (INIS)

Pujadas, M. C.; Camacho, C.; Guasp, M.; Villaescusa, J. I.

2009-01-01

In a double-blind randomized controlled clinical trial (RCT) subjects and researchers do not know the assignment to treatment groups to ovoid the appearance of subjective biases of information. The employment of radiopharmaceuticals in double-blind RCTs raises a dilemma from the point ov view of the radiological protection. On the one hand, the obligation to act in cases of contamination and/or risk of irradiation exists, but on the other hand the duty of keeping the blind study also exists. In this paper some of the possible problems that arise when conducting a double-blind RCT with radiopharmaceuticals from the point of view of the radiological protection are presented. We comment our experience with the radiopharmaceutical Alpharadin and, in addition, we propose useful recommendations based on the randomness of the decontamination process. (Author) 7 refs.

[The study on behaviour of protective equipment utilization of workers exposed to benzene and factors based on Planned Behavior Theory].

Science.gov (United States)

Huang, J Y; Liu, C D; Zhang, W M; Fu, Y K; Ma, H Y

2018-02-20

Objective: To investigate and predict the behavioral intention and mode of the protective equipment utilization selection of the workers who used Benzene, the Theory of Planned Behavior (TPB) was applied to establish the behavioral model to enhance the theoretical foundation for long-term intervention. Methods: Questionnaires were used to survey the 707 workers, and all the behaviors of using protective equipment were investigated. Evaluate the relationships between each variable and obtain the influence affects by structural equation model. Results: The investigation showed that 38.47% of the total workers (272 cases) used whole body protection, 13.58% used partially, and 16.69% didn't use any body protection. There were significant difference between the varying degrees in the four dimensions (behavioral attitude, perceived behavior control, subjective norm, and behavioral intention) (Pbehavior control was the most important influencing factor, subjective norm, positive attitude, negative attitude were the other three respects in sequence. The path co-efficient were 0.600、0.215、0.141 and 0.046 respectively. Conclusion: The study show that the theory of planned behavior can effectively explain the behavioral intention and behavior of protective equipment utilization. Therefore, combining the subjective initiative of individuals with the supervision of enterprises, In order to effectively enhance the protective equipment utilization of benzene workers.

Study of the trial subjects’ protection aspects in Phase I clinical trials and bioequivalence studies

Directory of Open Access Journals (Sweden)

K. O. Zupanets

2016-03-01

Full Text Available Protection of rights, health and well-being of persons who are taking the drug during the trial (trial subjects is one of the basic principles of clinical trials (CT management. Aim. In order to study key aspects of volunteer protection, determine factors that influence these indicators and estimate the importance of ensuring their proper implementation on the clinical site (CS three survey of 135 trial subjects were carried out to evaluate the importance of assessing the impact of factors such as the procedure of signing the informed consent (IC at the CS and testing procedures for HIV / AIDS, hepatitis and others. Assessment of the quality of life of trial subjects as indirect indicator of the quality of clinical trials that ensures the proper protection of their life was the subject of the third survey. Methods and results. The general model of the relationship between the key aspects of the trial subjects protection and the factors which are providing them during the clinical trials of drugs management was substantiated, which included the main aspects of the trial subjects’ protection, protective factors and basic CT management procedures, the impact of the above factors on the possibility of providing protection aspects depends on their implementation quality. It was found that trial subjects’ protection improvement can be achieved during the IC signing process. It is necessary to ensure a higher level of volunteers understanding of the terms that could be used in the IC form. Regarding the procedure of compulsory testing for HIV/AIDS in the course of screening, we can conclude that the majority of the trial subjects believe that this procedure is an additional factor in their health protection and do not consider it as an excessive psychological pressure on them. Conclusion. Assessing the quality of life during the bioequivalence study at the CS makes possible to reach a conclusion on general well-being and satisfaction with those

Parents' knowledge, attitudes and beliefs regarding sun protection in children: a qualitative study.

Science.gov (United States)

Littlewood, Zoe; Greenfield, Sheila

2018-02-01

Childhood is a critical period for sun protection, when the skin is particularly susceptible to the carcinogenic effects of ultraviolet radiation. Children are dependent upon parents to implement sun protective measures. Existing qualitative research exploring parents' attitudes and beliefs underpinning children's sun protection is from Australia, which has the highest melanoma incidence rates globally, and thus benefits from widespread sun protection awareness campaigns. Parents' sun protective behaviour may, therefore, differ between Australia and the UK. This study investigates the topic in a UK context, using qualitative methodology to gain detailed insights into a relatively under-researched area. The aim of the study was to explore parents' knowledge and understanding of sun protection in children, and factors that motivate and challenge them in this area. Finally, it aimed to determine if and how ethnicity and skin type influence these attitudes and beliefs. Twenty-two semi-structured individual interviews were carried out with parents of children aged 5 years or younger, recruited from local nurseries. Transcripts were analysed using thematic analysis. Four overarching themes emerged, each incorporating two to three sub-themes. 'Attitudes towards children's sun protection' refers to the fact that parents considered sun protection to be important for children, a finding which was consistent between different skin types. 'Sun protection practices' brings together several protective behaviours adopted in children and, to a lesser degree, in parents, and their associated disadvantages. 'Sun safety knowledge' refers to parents' awareness of the risks of sun exposure and the need for protection, and illustrates where gaps in knowledge exist, such as regarding the need for vitamin D, and the importance of vigilant sun protection even in the UK. Finally, 'motivating and facilitating factors' highlights motivations for sun protection in children, and factors that

On imperfect node protection in complex communication networks

International Nuclear Information System (INIS)

Xiao Shi; Xiao Gaoxi

2011-01-01

Motivated by recent research on complex networks, we study enhancing complex communication networks against intentional attack which takes down network nodes in a decreasing order of their degrees. Specifically, we evaluate an effect which has been largely ignored in existing studies; many real-life systems, especially communication systems, have protection mechanisms for their important components. Due to the existence of such protection, it is generally quite difficult to totally crash a protected node, though partially paralyzing it may still be feasible. Our analytical and simulation results show that such 'imperfect' protections generally speaking still help significantly enhance network robustness. Such insight may be helpful for the future developments of efficient network attack and protection schemes.

On imperfect node protection in complex communication networks

Energy Technology Data Exchange (ETDEWEB)

Xiao Shi [Hubei Province Key Laboratory of Intelligent Robot and School of Computer Science and Engineering, Wuhan Institute of Technology, Wuhan 430073 (China); Xiao Gaoxi, E-mail: xiao_moon2002@yahoo.com.cn, E-mail: egxxiao@ntu.edu.sg [Division of Communication Engineering, School of Electrical and Electronic Engineering, Nanyang Technological University, 639798 (Singapore)

2011-02-04

Motivated by recent research on complex networks, we study enhancing complex communication networks against intentional attack which takes down network nodes in a decreasing order of their degrees. Specifically, we evaluate an effect which has been largely ignored in existing studies; many real-life systems, especially communication systems, have protection mechanisms for their important components. Due to the existence of such protection, it is generally quite difficult to totally crash a protected node, though partially paralyzing it may still be feasible. Our analytical and simulation results show that such 'imperfect' protections generally speaking still help significantly enhance network robustness. Such insight may be helpful for the future developments of efficient network attack and protection schemes.

Positron annihilation in corrosion protective polymeric coatings. Pt. 2

International Nuclear Information System (INIS)

Szeles, C.; Vertes, A.; White, M.L.; Leidheiser, H. Jr.; Lehigh Univ., Bethlehem, PA

1988-01-01

Positron annihilation was studied in four commercial polymeric coatings on iron. Positron lifetime measurements were performed before and after exposure of the coatings to boiling water for 1 h. A correlation was observed between the effect of water exposure on the lifetime spectra and the protective properties of the coatings when exposed to 0.1M sulfuric acid at 60 0 C for 1010 h. The coatings that provided good corrosion protection in the acid showed minor changes in the positron lifetime spectra upon exposure to water. The spectra of coatings that showed poor corrosion protection in the acid showed minor changes in the positron lifetime spectra upon exposure to water. The spectra of coatings that showed poor corrosion protection, on the other hand, exhibited considerable changes in the positron lifetime spectra upon exposure to water. (orig.)

An overview of recent projects to study thermal protection in life rafts, lifeboats and immersion suits

Energy Technology Data Exchange (ETDEWEB)

Mak, L.; DuCharme, M. B.; Farnworth, B.; Wissler, E. H.; Brown, R.; Kuczora, A. [Maritime and Arctic Survival Scientific and Engineering Ressearch Team (Canada)

2011-07-01

Survival during a marine evacuation in cold regions is very challenging. However international regulations do not require specific thermal protection or ventilation performance criteria for lifeboats. In the same way, the testing methods for approval testing of immersion suits are not standardised. This paper investigated recent projects completed or on-going to study thermal protection in life rafts, lifeboats and immersion suits. An overview of several projects from the Maritime and Arctic Survival Scientific and Engineering Research Team (MASSERT) was conducted. This review provided the necessary knowledge to advance international standards and develop the thermal protection requirements for survival in the Arctic. The results showed the MASSERT correlated thermal insulation values between human subjects and thermal manikins in life rafts and in immersion suits. It was found that the manikins are a valuable evaluation tool, as well as the computerised models used as prediction tools.

Compatibility Study of Protective Relaying in a Grid-Connected Fuel Cell

Energy Technology Data Exchange (ETDEWEB)

Staunton, R.H.

2004-04-15

A 200-kW fuel cell produced by International Fuel Cells (IFC), a United Technologies Company, began operation at the National Transportation Research Center (NTRC) in early June 2003. The NTRC is a joint Oak Ridge National laboratory (ORNL) and University of Tennessee research facility located in Knoxville, Tennessee. This research activity investigated the protective relaying functions of this fully commercialized fuel cell power plant, which uses ''synthesized'' protective relays. The project's goal is to characterize the compatibility between the fuel cell's interconnection protection system and the local distribution system or electric power system (EPS). ORNL, with assistance from the Electric Power Research Institute-Power Electronics Applications Center (EPRI-PEAC) in Knoxville, Tennessee, monitored and characterized the system compatibility over a period of 6 months. Distribution utility engineers are distrustful of or simply uncomfortable with the protective relaying and hardware provided as part of distributed generation (DG) plants. Part of this mistrust is due to the fact that utilities generally rely on hardware from certain manufacturers whose reliability is well established based on performance over many years or even decades. Another source of concern is the fact that fuel cells and other types of DG do not use conventional relays but, instead, the protective functions of conventional relays are simulated by digital circuits in the distributed generator's grid interface control unit. Furthermore, the testing and validation of internal protection circuits of DG are difficult to accomplish and can be changed by the vendor at any time. This study investigated and documented the safety and protective relaying present in the IFC fuel cell, collected data on the operation of the fuel cell, recorded event data during EPS disturbances, and assessed the compatibility of the synthesized protective circuits and the local

Demographic Differences in Sun Protection Beliefs and Behavior: A Community-Based Study in Shanghai, China

Directory of Open Access Journals (Sweden)

Shuxian Yan

2015-03-01

Full Text Available Objective: We want to know the attitudes and behaviors towards UV protection and we want to analyze the difference between different Chinese demographic groups in this study. Methods: A community-based study was undertaken in Shanghai from October 2009 to January 2010. The participants, ages 20–60 years old, were screened by cluster sampling and were investigated through interviews at their own homes. Personal basic information and questions pertaining to their knowledge and attitudes towards sunlight and sun protective activities were included in the questionnaire. Results: We completed 5964 questionnaires (2794 men and 3170 women. Eighty-six percent of the respondents belonged to Fitzpatrick skin type IV. Knowledge about UV-induced risks was known by more than half of the participants. However, only one-third of the participants thought they needed sun protection in winter and indoors or in vehicles, and 27% of the participants acknowledged tanning was not favorable. The attitudes towards sun exposure varied greatly, showing significant differences based on gender, age, socioeconomic groups and skin type groups (p < 0.05. Fifty-five percent of the participants never use an umbrella under sunlight, only 26.5% of the respondents wear hats, and 21.3% of the participants applied sunscreen. Females and individuals of a younger age and higher education level were more likely to perform sun-protective behaviors than males and those of an older age and lower education level (p < 0.001. Conclusion: There is a deficit in the use of sun protection existing in our surveyed Chinese population, especially in males and lower socioeconomic population, which could allow for planning prevention campaigns and exploring sun-preventive products.

Wake Shield Target Protection

International Nuclear Information System (INIS)

Valmianski, Emanuil I.; Petzoldt, Ronald W.; Alexander, Neil B.

2003-01-01

The heat flux from both gas convection and chamber radiation on a direct drive target must be limited to avoid target damage from excessive D-T temperature increase. One of the possibilities of protecting the target is a wake shield flying in front of the target. A shield will also reduce drag force on the target, thereby facilitating target tracking and position prediction. A Direct Simulation Monte Carlo (DSMC) code was used to calculate convection heat loads as boundary conditions input into ANSYS thermal calculations. These were used for studying the quality of target protection depending on various shapes of shields, target-shield distance, and protective properties of the shield moving relative to the target. The results show that the shield can reduce the convective heat flux by a factor of 2 to 5 depending on pressure, temperature, and velocity. The protective effect of a shield moving relative to the target is greater than the protective properties of a fixed shield. However, the protective effect of a shield moving under the drag force is not sufficient for bringing the heat load on the target down to the necessary limit. Some other ways of diminishing heat flux using a protective shield are discussed

A Multiple siRNA-Based Anti-HIV/SHIV Microbicide Shows Protection in Both In Vitro and In Vivo Models.

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Sandhya Boyapalle

Full Text Available Human immunodeficiency virus (HIV types 1 and 2 (HIV-1 and HIV-2 are the etiologic agents of AIDS. Most HIV-1 infected individuals worldwide are women, who acquire HIV infections during sexual contact. Blocking HIV mucosal transmission and local spread in the female lower genital tract is important in preventing infection and ultimately eliminating the pandemic. Microbicides work by destroying the microbes or preventing them from establishing an infection. Thus, a number of different types of microbicides are under investigation, however, the lack of their solubility and bioavailability, and toxicity has been major hurdles. Herein, we report the development of multifunctional chitosan-lipid nanocomplexes that can effectively deliver plasmids encoding siRNA(s as microbicides without adverse effects and provide significant protection against HIV in both in vitro and in vivo models. Chitosan or chitosan-lipid (chlipid was complexed with a cocktail of plasmids encoding HIV-1-specific siRNAs (psiRNAs and evaluated for their efficacy in HEK-293 cells, PBMCs derived from nonhuman primates, 3-dimensional human vaginal ectocervical tissue (3D-VEC model and also in non-human primate model. Moreover, prophylactic administration of the chlipid to deliver a psiRNA cocktail intravaginally with a cream formulation in a non-human primate model showed substantial reduction of SHIV (simian/human immunodeficiency virus SF162 viral titers. Taken together, these studies demonstrate the potential of chlipid-siRNA nanocomplexes as a potential genetic microbicide against HIV infections.

Representation of Ecosystem Services by Terrestrial Protected Areas: Chile as a Case Study

Science.gov (United States)

Durán, América P.; Casalegno, Stefano; Marquet, Pablo A.; Gaston, Kevin J.

2013-01-01

Protected areas are increasingly considered to play a key role in the global maintenance of ecosystem processes and the ecosystem services they provide. It is thus vital to assess the extent to which existing protected area systems represent those services. Here, for the first time, we document the effectiveness of the current Chilean protected area system and its planned extensions in representing both ecosystem services (plant productivity, carbon storage and agricultural production) and biodiversity. Additionally, we evaluate the effectiveness of protected areas based on their respective management objectives. Our results show that existing protected areas in Chile do not contain an unusually high proportion of carbon storage (14.9%), agricultural production (0.2%) or biodiversity (11.8%), and also represent a low level of plant productivity (Normalized Difference Vegetation Index of 0.38). Proposed additional priority sites enhance the representation of ecosystem services and biodiversity, but not sufficiently to attain levels of representation higher than would be expected for their area of coverage. Moreover, when the species groups were assessed separately, amphibians was the only one well represented. Suggested priority sites for biodiversity conservation, without formal protection yet, was the only protected area category that over-represents carbon storage, agricultural production and biodiversity. The low representation of ecosystem services and species’ distribution ranges by the current protected area system is because these protected areas are heavily biased toward southern Chile, and contain large extents of ice and bare rock. The designation and management of proposed priority sites needs to be addressed in order to increase the representation of ecosystem services within the Chilean protected area system. PMID:24376559

Lithium as a prooxidant? A possible protective role of selenium – in vitro study

Directory of Open Access Journals (Sweden)

Irena Musik

2017-09-01

In Vero cells lithium decreased all studied parameters, particularly GPx. Selenium co-treatment showed a distinct protective effect. In FaDu cells the similar effect was observed only in case of GSH. The results point to differences in action of lithium and selenium in physiological and pathological state. As long-term lithium therapy is applied in psychiatric patients the results regarding Vero line let suggest that selenium might be considered as an adjuvant alleviating side effects of Li-treatment.

Nephro-protective potential of Morus alba, a prospective experimental study on animal models.

Science.gov (United States)

Ullah, Naveed; Khan, Mir Azam; Khan, Salimullah; Ahmad, Habib; Asif, Afzal Haq; Khan, Taous

2016-01-01

Morus alba L. (Moraceae) is traditionally used for the treatment of urinary incontinency due its strong diuretic properties. The present study explores the renal protective effects of M. alba, due to its free radical scavenging properties, in order to provide experimental evidence for its established use. Ethanolic extract (200 mg/kg/d) derived from M. alba fruit was employed in rabbits as a co-therapy (GM-al) with gentamicin (80 mg/kg/d) for a period of 3 weeks. Biochemical kidney functioning parameters, urinary isozymes, and histopathological examination were performed. The results showed that ethanol extract of Morus alba L. prevented alterations in serum creatinine (4.02 ± 0.14, p alba with gentamicin prevented renal functioning alterations expected with the use of gentamicin alone. Therefore, it can be concluded that M. alba to protect from kidney damage, which may be because of its free radical scavenging and diuretic properties.

Protecting the Amazon with protected areas

Science.gov (United States)

Walker, Robert; Moore, Nathan J.; Arima, Eugenio; Perz, Stephen; Simmons, Cynthia; Caldas, Marcellus; Vergara, Dante; Bohrer, Claudio

2009-01-01

This article addresses climate-tipping points in the Amazon Basin resulting from deforestation. It applies a regional climate model to assess whether the system of protected areas in Brazil is able to avoid such tipping points, with massive conversion to semiarid vegetation, particularly along the south and southeastern margins of the basin. The regional climate model produces spatially distributed annual rainfall under a variety of external forcing conditions, assuming that all land outside protected areas is deforested. It translates these results into dry season impacts on resident ecosystems and shows that Amazonian dry ecosystems in the southern and southeastern basin do not desiccate appreciably and that extensive areas experience an increase in precipitation. Nor do the moist forests dry out to an excessive amount. Evidently, Brazilian environmental policy has created a sustainable core of protected areas in the Amazon that buffers against potential climate-tipping points and protects the drier ecosystems of the basin. Thus, all efforts should be made to manage them effectively. PMID:19549819

Novel therapy for renal protection.

Science.gov (United States)

Zarbock, Alexander; Milles, Kindgen

2015-08-01

Acute kidney injury (AKI) is a common and serious complication that significantly increases morbidity, mortality, and cost of care after surgery. In this article, we review recent studies that deal with strategies for renal protection and the prevention of AKI after surgery. A prerequisite for any prophylactic intervention is the identification of patients at risk for AKI or those with acute kidney damage before kidney function deteriorates. In this context, new biomarkers can help to detect cellular injury early. This way, a window for interventions can be opened. Several studies demonstrated the tissue-protective effect of remote ischemic preconditioning in various organs. There is clear evidence that use of balanced crystalloid fluids and the avoidance of hyperchloremic solutions for infusion therapy can reduce the incidence of AKI. Preliminary data show a protective effect if dexmedetomidine is used as a sedative agent following cardiac surgery. The most important intervention with proven efficacy to protect from AKI is aggressive hemodynamic stabilization. Early identification of patients at risk for AKI is crucial to apply any protective intervention. An improved perioperative management is required to prevent AKI. Although pharmacological therapies aiming to protect AKI are under evaluation, hemodynamic optimization and avoidance of nephrotoxic drugs are critical for perioperative patient.

Gun Shows and Gun Violence: Fatally Flawed Study Yields Misleading Results

Science.gov (United States)

Hemenway, David; Webster, Daniel; Pierce, Glenn; Braga, Anthony A.

2010-01-01

A widely publicized but unpublished study of the relationship between gun shows and gun violence is being cited in debates about the regulation of gun shows and gun commerce. We believe the study is fatally flawed. A working paper entitled “The Effect of Gun Shows on Gun-Related Deaths: Evidence from California and Texas” outlined this study, which found no association between gun shows and gun-related deaths. We believe the study reflects a limited understanding of gun shows and gun markets and is not statistically powered to detect even an implausibly large effect of gun shows on gun violence. In addition, the research contains serious ascertainment and classification errors, produces results that are sensitive to minor specification changes in key variables and in some cases have no face validity, and is contradicted by 1 of its own authors’ prior research. The study should not be used as evidence in formulating gun policy. PMID:20724672

Spatial occupancy models applied to atlas data show Southern Ground Hornbills strongly depend on protected areas.

Science.gov (United States)

Broms, Kristin M; Johnson, Devin S; Altwegg, Res; Conquest, Loveday L

2014-03-01

Determining the range of a species and exploring species--habitat associations are central questions in ecology and can be answered by analyzing presence--absence data. Often, both the sampling of sites and the desired area of inference involve neighboring sites; thus, positive spatial autocorrelation between these sites is expected. Using survey data for the Southern Ground Hornbill (Bucorvus leadbeateri) from the Southern African Bird Atlas Project, we compared advantages and disadvantages of three increasingly complex models for species occupancy: an occupancy model that accounted for nondetection but assumed all sites were independent, and two spatial occupancy models that accounted for both nondetection and spatial autocorrelation. We modeled the spatial autocorrelation with an intrinsic conditional autoregressive (ICAR) model and with a restricted spatial regression (RSR) model. Both spatial models can readily be applied to any other gridded, presence--absence data set using a newly introduced R package. The RSR model provided the best inference and was able to capture small-scale variation that the other models did not. It showed that ground hornbills are strongly dependent on protected areas in the north of their South African range, but less so further south. The ICAR models did not capture any spatial autocorrelation in the data, and they took an order, of magnitude longer than the RSR models to run. Thus, the RSR occupancy model appears to be an attractive choice for modeling occurrences at large spatial domains, while accounting for imperfect detection and spatial autocorrelation.

Protective equipment of radiological protection and the worker wear

International Nuclear Information System (INIS)

Cassia, Flor Rita de; Huhn, Andrea; Lima, Gelbcke Francine

2013-01-01

This qualitative research with workers of seven hemodynamic service of Santa Catarina, Brazil aimed to analyze the use of radiological protection equipment (RPE), as well as wear to the health of workers who use these causes. The study was conducted between March 2010 and November 2010, totaling approximately 30 hours of observations. Results showed resistance to the use of RPE and also showed wear to workers' health, mainly due to the weight and discomfort they cause, as may weigh 7-9 pounds, depending on the model used. Evidenced also the absence of workers due herniated disc, back pain, and other musculo skeletal problems. These complaints, in addition to being related to the use of these protective gear also related with the time that workers remain standing for long periods on certain procedures, such as angioplasty. Given these results, the research recommended the use of these devices with materials, that are already being produced, making lighter aprons, thus avoiding fatigue and back pain and also provide greater comfort by reducing workers' resistance to its use and its adverse consequences

Evolution of the radiological protection policy. Applications in developing countries. IPEN a case of study

International Nuclear Information System (INIS)

Gordon, A.M.P.L.; Sordi, G.M.A. A.

2006-01-01

This paper aims to show the radiological protection development in Brazil from the beginning, when President Joao Cafe Filho signed an agreement with the U.S.A. In this agreement, Brazil joined the 'Atoms for Peace' program established on August 3., 1955. Yet in 1955, Brazil participated as a foundation member in the International Atomic Energy Agency (IAEA). As a result, the Iea - 'Instituto de Energia Atomica'- was created on August 31., 1956 and a research reactor type swimming pool was installed to produce radioisotopes and prepare experts in the field of nuclear activities. This reactor is maintained in operation at the Instituto de Pesquisas Energeticas e Nucleares (IPEN), former Iea. Having the Iea as a case of study, we analyze the radiological protection evolution during the fifty years of its life. We correlate this development with the Brazilian National Nuclear Energy Commission (CNEN) Regulations. CNEN was also created in 1956. The first safety standard in Brazil was delivered in 1973. Therefore, this paper will focus the radiological protection development at national level. Both institutions followed the international radiological protection recommendations, under the difficulties imposed by the historical conditions of a developing country. In order to have an outline of the radiological protection development, we inform that it was started as a section of the Radiological Division at the Iea. At that time, the Iea had four divisions. The radiological protection was performed by four people, being two physicists and two technicians that accomplished all the duties. On that occasion, approximately 30 people operated the Iea. The work staff at IPEN increased, arriving to 1600 people in 1998, including 150 persons in the radiological protection activities. Nowadays, 1200 people, including 100 persons in the health physics duties operate the IPEN. (authors)

Evolution of the radiological protection policy. Applications in developing countries. IPEN a case of study

Energy Technology Data Exchange (ETDEWEB)

Gordon, A.M.P.L.; Sordi, G.M.A. A. [Instituto de Pesquisas Energeticas e Nucleares - IPEN, Sao Paulo (Brazil)

2006-07-01

This paper aims to show the radiological protection development in Brazil from the beginning, when President Joao Cafe Filho signed an agreement with the U.S.A. In this agreement, Brazil joined the 'Atoms for Peace' program established on August 3., 1955. Yet in 1955, Brazil participated as a foundation member in the International Atomic Energy Agency (IAEA). As a result, the Iea - 'Instituto de Energia Atomica'- was created on August 31., 1956 and a research reactor type swimming pool was installed to produce radioisotopes and prepare experts in the field of nuclear activities. This reactor is maintained in operation at the Instituto de Pesquisas Energeticas e Nucleares (IPEN), former Iea. Having the Iea as a case of study, we analyze the radiological protection evolution during the fifty years of its life. We correlate this development with the Brazilian National Nuclear Energy Commission (CNEN) Regulations. CNEN was also created in 1956. The first safety standard in Brazil was delivered in 1973. Therefore, this paper will focus the radiological protection development at national level. Both institutions followed the international radiological protection recommendations, under the difficulties imposed by the historical conditions of a developing country. In order to have an outline of the radiological protection development, we inform that it was started as a section of the Radiological Division at the Iea. At that time, the Iea had four divisions. The radiological protection was performed by four people, being two physicists and two technicians that accomplished all the duties. On that occasion, approximately 30 people operated the Iea. The work staff at IPEN increased, arriving to 1600 people in 1998, including 150 persons in the radiological protection activities. Nowadays, 1200 people, including 100 persons in the health physics duties operate the IPEN. (authors)

Contingent Valuation of Watershed Protection in Nigeria: A Case Study

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Femi Olokesusi

2013-07-01

This paper focusses on the use of the willingness-to-pay (WTP approach for determining the amount of money that people in selected large-scale irrigation and dam project areas in the Sudano-Saludian zone of Nigeria are willing to forego for the sake of environmental protection in the watershed. After a general description of the problems and approaches to valuing and monetising environmental resources and their protection, the details of the study findings and policy implications are discussed.

bioA mutant of Mycobacterium tuberculosis shows severe growth defect and imparts protection against tuberculosis in guinea pigs

Science.gov (United States)

Kar, Ritika; Nangpal, Prachi; Mathur, Shubhita; Singh, Swati

2017-01-01

Owing to the devastation caused by tuberculosis along with the unsatisfactory performance of the Bacillus Calmette–Guérin (BCG) vaccine, a more efficient vaccine than BCG is required for the global control of tuberculosis. A number of studies have demonstrated an essential role of biotin biosynthesis in the growth and survival of several microorganisms, including mycobacteria, through deletion of the genes involved in de novo biotin biosynthesis. In this study, we demonstrate that a bioA mutant of Mycobacterium tuberculosis (MtbΔbioA) is highly attenuated in the guinea pig model of tuberculosis when administered aerogenically as well as intradermally. Immunization with MtbΔbioA conferred significant protection in guinea pigs against an aerosol challenge with virulent M. tuberculosis, when compared with the unvaccinated animals. Booster immunization with MtbΔbioA offered no advantage over a single immunization. These experiments demonstrate the vaccinogenic potential of the attenuated M. tuberculosis bioA mutant against tuberculosis. PMID:28658275

bioA mutant of Mycobacterium tuberculosis shows severe growth defect and imparts protection against tuberculosis in guinea pigs.

Directory of Open Access Journals (Sweden)

Ritika Kar

Full Text Available Owing to the devastation caused by tuberculosis along with the unsatisfactory performance of the Bacillus Calmette-Guérin (BCG vaccine, a more efficient vaccine than BCG is required for the global control of tuberculosis. A number of studies have demonstrated an essential role of biotin biosynthesis in the growth and survival of several microorganisms, including mycobacteria, through deletion of the genes involved in de novo biotin biosynthesis. In this study, we demonstrate that a bioA mutant of Mycobacterium tuberculosis (MtbΔbioA is highly attenuated in the guinea pig model of tuberculosis when administered aerogenically as well as intradermally. Immunization with MtbΔbioA conferred significant protection in guinea pigs against an aerosol challenge with virulent M. tuberculosis, when compared with the unvaccinated animals. Booster immunization with MtbΔbioA offered no advantage over a single immunization. These experiments demonstrate the vaccinogenic potential of the attenuated M. tuberculosis bioA mutant against tuberculosis.

Examining Self-Protection Measures Guarding Adult Protective Services Social Workers against Compassion Fatigue

Science.gov (United States)

Bourassa, Dara

2012-01-01

Little research has focused on the risk factors, effects, and experiences of compassion fatigue among gerontological social workers. This qualitative study explores the experiences and perspectives of nine Adult Protective Services (APS) social workers in relation to compassion fatigue. Results show that the APS social workers combined personal…

[Do double gloves protect against contamination during cannulation of blood vessels? A prospective randomized study].

Science.gov (United States)

Szarpak, Łukasz; Kurowski, Andrzej

2014-01-01

Undamaged medical gloves protect medical personnel from contact with physiological fluids of the patient. Thus they protect the assistance provider from hand skin contamination with potentially infectious biological materials. The aim of the study was to evaluate the occurrence of pierce, perforations or damage of medical gloves during cannulation of blood vessels. In the prospective randomized study 303 pairs of gloves, used during cannulation of blood vessels under simulated resuscitation, were analyzed. Gloves were tested by the water leak test. The water test revealed 44 cases of damage to the gloves used during cannulation of blood vessels. Significant differences were noted in the frequency of damage to both the outer and single pairs of gloves and the inner pair of gloves. The study showed that the use of double gloves provides a higher level of security for a paramedic than the use of a single pair of gloves, however, double gloves reduce the manual dexterity of a paramedic. A large number of damages to gloves are not noticed by medical personnel during surgery.

An Examination of Organizational Information Protection in the Era of Social Media: A Study of Social Network Security and Privacy Protection

Science.gov (United States)

Maar, Michael C.

2013-01-01

This study investigates information protection for professional users of online social networks. It addresses management's desire to motivate their employees to adopt protective measures while accessing online social networks and to help their employees improve their proficiency in information security and ability to detect deceptive…

Advanced Protection & Service Restoration for FREEDM Systems

Science.gov (United States)

Singh, Urvir

A smart electric power distribution system (FREEDM system) that incorporates DERs (Distributed Energy Resources), SSTs (Solid State Transformers - that can limit the fault current to two times of the rated current) & RSC (Reliable & Secure Communication) capabilities has been studied in this work in order to develop its appropriate protection & service restoration techniques. First, a solution is proposed that can make conventional protective devices be able to provide effective protection for FREEDM systems. Results show that although this scheme can provide required protection but it can be quite slow. Using the FREEDM system's communication capabilities, a communication assisted Overcurrent (O/C) protection scheme is proposed & results show that by using communication (blocking signals) very fast operating times are achieved thereby, mitigating the problem of conventional O/C scheme. Using the FREEDM System's DGI (Distributed Grid Intelligence) capability, an automated FLISR (Fault Location, Isolation & Service Restoration) scheme is proposed that is based on the concept of 'software agents' & uses lesser data (than conventional centralized approaches). Test results illustrated that this scheme is able to provide a global optimal system reconfiguration for service restoration.

Effect of Remote Back-Up Protection System Failure on the Optimum Routine Test Time Interval of Power System Protection

Directory of Open Access Journals (Sweden)

Y Damchi

2013-12-01

Full Text Available Appropriate operation of protection system is one of the effective factors to have a desirable reliability in power systems, which vitally needs routine test of protection system. Precise determination of optimum routine test time interval (ORTTI plays a vital role in predicting the maintenance costs of protection system. In the most previous studies, ORTTI has been determined while remote back-up protection system was considered fully reliable. This assumption is not exactly correct since remote back-up protection system may operate incorrectly or fail to operate, the same as the primary protection system. Therefore, in order to determine the ORTTI, an extended Markov model is proposed in this paper considering failure probability for remote back-up protection system. In the proposed Markov model of the protection systems, monitoring facility is taken into account. Moreover, it is assumed that the primary and back-up protection systems are maintained simultaneously. Results show that the effect of remote back-up protection system failures on the reliability indices and optimum routine test intervals of protection system is considerable.

Protective Behavior in Games

NARCIS (Netherlands)

Fiestras-Janeiro, G.; Borm, P.E.M.; van Megen, F.J.C.

1996-01-01

This paper introduces the notion of protective equilibrium in the context of fin ite games in strategic form.It shows that for matrix games the set of protective equilibria equals the set of proper equilibria.Moreover, in the context of bima trix games, the notion of protective behaviour is used as

Environmental protection: Shifting the focus toward the protected object

Directory of Open Access Journals (Sweden)

Cvetić Radenka

2013-01-01

Full Text Available This article is an attempt to provide a comprehensive overview of the rationale which led to developments in the law of environmental protection in a direction of an even more efficient protection of environment from human beings. There has been a transformation of the constitutionally protected right to a healthy environment to the Constitutional guarantee which involves both duty and responsibility for its protection. There has also been a shift from declaratory protection toward enforceable prohibitions and orders. These transformations have occurred when the society faced, under dramatic circumstances, the situation which shows that failure to protect the common good could lead to catastrophic consequences. The system of environmental protection, which enables sustainable development, is based on the primacy of the precautionary principle which deals with prevention and reduction of probability of harm, as well as on the no fault liability of the polluter for the environmental harm even in the absence of the claim for damages. The efficacy of the environmental protection could be improved by raising the awareness of the preservation of environment. The understanding that the protection of environment amounts to a survival of a mankind could lead to creating rights for the environment as such.

Protection from sunburn with beta-Carotene--a meta-analysis.

Science.gov (United States)

Köpcke, Wolfgang; Krutmann, Jean

2008-01-01

Nutritional protection against skin damage from sunlight is increasingly advocated to the general public, but its effectiveness is controversial. In this meta-analysis, we have systematically reviewed the existing literature on human supplementation studies on dietary protection against sunburn by beta-carotene. A review of literature until June 2007 was performed in PubMed, ISI Web of Science and EBM Cochrane library and identified a total of seven studies which evaluated the effectiveness of beta-carotene in protection against sunburn. Data were abstracted from these studies by means of a standardized data collection protocol. The subsequent meta-analysis showed that (1) beta-carotene supplementation protects against sunburn and (2) the study duration had a significant influence on the effected size. Regression plot analysis revealed that protection required a minimum of 10 weeks of supplementation with a mean increase of the protective effect of 0.5 standard deviations with every additional month of supplementation. Thus, dietary supplementation of humans with beta-carotene provides protection against sunburn in a time-dependent manner.

To protect or not to protect: examining reasons for sun protection among young women at risk for skin cancer.

Science.gov (United States)

Auerbach, M V; Heckman, C J; Darlow, S

2018-03-27

We aimed to further the understanding of the low rates of sun protection in young women at risk for skin cancer. Six-hundred-sixty-one daily diary entries were received via text message over 14 days from 56 young women at moderate to high risk of developing skin cancer. Women reported whether or not they used sun protection and also listed what their reasons were for using protection or not using sun protection each day. Multi-level modeling was used to examine the influence of study variables when predicting daily sun protection or lack of protection. The number of days in which sun protection was reported was positively associated with "habit" and "prevention" as reasons for protection and negatively associated with "not-needed" and "unprepared" as reasons for non-protection. Self-reported sun protection increased over the 14-day study period. Results of this study suggest the potential value of interventions aimed at motives for sun-protection behaviors.

A policy study in strengthening the national infrastructure for radiation protection

Energy Technology Data Exchange (ETDEWEB)

Park, Chan Il [Korean Association for Radiation Protection, Seoul (Korea, Republic of); Lee, Jai Ki; Chang, Jaik Won; Lee, Choon Sik [Hanyang Univ., Seoul (Korea, Republic of); Whang, Joo Ho; Kim, Ki Ho [Kyunghee Univ., Seoul (Korea, Republic of)

1999-03-15

Public attitude declined further toward against the nuclear technology and eventually caused undue societal costs. Since the general public are aware of, or even afraid of, effects of radiation, it is hard to expect successful nuclear program without making them ease about radiation. In order to make the public feel easy and think that they get adequate protection, the infrastructure for radiation protection should be strengthened to the level corresponding to the utilization of nuclear/radiation technologies in the country. Public confidence in the role of the regulatory body is utmost important. The objectives of this study are to figure out a good model of regulatory body for radiation protection in Korea and to promulgate a draft legislations including provisions on the competent authority, the national policy and programs for upgraded infrastructure for radiation protection. As an appropriate form for the regulatory body in Korea, 'board of nuclear and radiation regulation', an independent and specialized organization under the direction of the prime minister, was proposed. It is expected that disadvantages dominate if the organization for radiation protection is separated from one for nuclear regulation. The proposed draft radiation protection acts consist of 8 chapters and 55 articles and some supplementary provisions. Copious footnotes provide explanations of the articles including the basis, considerations. justification.

Studies on toxicity, anti-stress and hepato-protective properties of Kombucha tea.

Science.gov (United States)

Pauline, T; Dipti, P; Anju, B; Kavimani, S; Sharma, S K; Kain, A K; Sarada, S K; Sairam, M; Ilavazhagan, G; Devendra, K; Selvamurthy, W

2001-09-01

The objective of the study was to evaluate toxicity, anti-stress activity and hepato-protective properties of Kombucha tea. Kombucha tea was fed orally for 15 days using three different doses i.e. normal dose, five and ten times the dose. Rats were then sacrificed and various biochemical, and histological parameters were estimated. Anti-stress activity was evaluated either by 1) by exposing animals to cold and hypoxia and estimating the levels of malondialdehyde and reduced glutathione in plasma/blood or 2) by subjecting the animals to restraint stress and recording faecal output. Hepato-toxicity was induced by challenging the animals to an acute dose of paracetamol (1 gm/kg) orally and determining the plasma levels of SGPT, SGOT and MDA. The effect of oral administration of different doses of K-tea to albino rats was examined and the results indicate that K-tea has no significant toxicity as revealed by various biochemical and histopathological parameters. K-tea has been found to prevent lipid peroxidation and fall in reduced glutathione level when rats were exposed to cold and hypoxia in simulated chamber. Further, K-tea has also been found to decrease the Wrap-restraint faecal pellet output in rats. K-tea has also been found to decrease paracetamol induced hepatotoxicity significantly. The study shows that K-tea has anti-stress and hepato-protective activities.

Protective Behavior in Games

OpenAIRE

Fiestras-Janeiro, G.; Borm, P.E.M.; van Megen, F.J.C.

1996-01-01

This paper introduces the notion of protective equilibrium in the context of fin ite games in strategic form.It shows that for matrix games the set of protective equilibria equals the set of proper equilibria.Moreover, in the context of bima trix games, the notion of protective behaviour is used as a refinement tool.

Study of Physical Protection System at PUSPATI TRIGA Reactor (RTP)

International Nuclear Information System (INIS)

Ligam, A.S.; Ina, I.; Zarina Masood

2016-01-01

Physical protection program at PUSPATI TRIGA Reactor (RTP) which is located at Nuklear Malaysia, Bangi Complex has been strengthened and upgraded from time to time to accommodate current situation needs. However, there is always room for improvement. Hence, study have been made to look deeper into physical protection components such as delay systems, external sensors, PPS intruder alarm sensors, use of video system, personnel security or insider threats, access control operation system operation rules and security culture that may need to take into consideration. (author)

Experimental and theoretical studies on radiation protective effect of a lighter non-lead protective apron

International Nuclear Information System (INIS)

Takano, Yoshihisa; Ono, Koji; Okazaki, Keiichiro

2005-01-01

Non-lead aprons using composite materials are often used for radiation protective aprons instead of heavy lead aprons. However, the protective effect of the lighter, non-lead aprons has not been well evaluated, and it is not yet clear how they compare with lead aprons. Therefore, we investigated the protective performance of non-lead aprons theoretically and experimentally by comparing them with lead aprons under clinical conditions. We measured the energy spectra for direct and scattered-rays passing through protective aprons or not, and measured doses with glass dosimeters for validation of theoretical calculations based on the energy spectra. We found that the protective effect of non-lead aprons was higher than that of lead aprons at X-ray of tube voltages of 70-100 kV, which are often used for radiography and fluorography. This demonstrated that the non-lead aprons are more useful in many situations than heavy lead aprons. (author)

Analyzing nature's protective design: The glyptodont body armor.

Science.gov (United States)

du Plessis, Anton; Broeckhoven, Chris; Yadroitsev, Igor; Yadroitsava, Ina; le Roux, Stephan Gerhard

2018-06-01

Many animal species evolved some form of body armor, such as scales of fish and bony plates or osteoderms of reptiles. Although a protective function is often taken for granted, recent studies show that body armor might comprise multiple functionalities and is shaped by trade-offs among these functionalities. Hence, despite the fact that natural body armor might serve as bio-inspiration for the development of artificial protective materials, focussing on model systems in which body armor serves a solely protective function might be pivotal. In this study, we investigate the osteoderms of Glyptotherium arizonae, an extinct armadillo-like mammal in which body armor evolved as protection against predators and/or tail club blows of conspecifics. By using a combination of micro-computed tomography, reverse-engineering, stress simulations and mechanical testing of 3D printed models, we show that the combination of dense compact layers and porous lattice core might provide an optimized combination of strength and high energy absorption. Copyright © 2018 Elsevier Ltd. All rights reserved.

Determinants of the Intention to Protect Personal Information among Facebook Users

Directory of Open Access Journals (Sweden)

Bum Soo Chon

2018-02-01

Full Text Available This study aimed to examine predictors of the intention to protect personal information on Facebook. We conducted an online survey of 679 Facebook users in the Republic of Korea. The findings of this study showed that usefulness and ease of use had significant effects on attitudes toward protection behavior. The results also revealed that risk factors (privacy risk severity and vulnerability had significant effects on protective behaviors. Based on our findings, we discussed the information protection of privacy on Facebook.

Duet for menstrual protection: a feasibility study in Zimbabwe.

Science.gov (United States)

Averbach, Sarah; Sahin-Hodoglugil, Nuriye; Musara, Petina; Chipato, Tsungai; van der Straten, Ariane

2009-06-01

Managing menses is a challenge for women in developing countries. Duet is a cervical barrier being developed for contraception and STI prevention. We explored the hypothetical acceptability of using Duet as a menstrual cup, among Zimbabwean women. A survey and focus group discussions (FGD) were conducted with 43 women aged 18-45 years to gain information about their menstrual practices and attitudes regarding the use of Duet for menstrual protection. All 43 women reported that if Duet were available, they would "definitely" try it, and that it was "very important" that Duet is low cost and easy to clean; 86% reported that using it would make a difference in their lives. FGD findings highlighted unhygienic practices due to the lack of affordable options for menstrual management and a genuine interest in Duet, including its potential use for multiple purposes (contraception, disease prevention and menstrual protection). Accessing affordable and hygienic menstrual protection was a problem for these Zimbabwean women. Duet appeared acceptable and it would be feasible to conduct a user-acceptability study of Duet as a menstrual cup in Zimbabwe.

Permeation of Comite through protective gloves.

Science.gov (United States)

Zainal, Hanaa; Que Hee, Shane S

2006-09-01

The goal of the study was to assess how protective disposable (Safeskin) and chemical protective (Sol-Vex) nitrile gloves were against Comite emulsifiable concentrate formulation containing propargite (PROP) as active pesticidal ingredient, because there were no explicit recommendations for the gloves that should be worn for hand protection. The glove material was exposed in ASTM-type I-PTC-600 permeation cells at 30.0+/-0.5 degrees C, and gas chromatography-mass spectrometry used for PROP analysis. Aqueous solutions of Comite at 40.4 mg/mL permeated both Safeskin and Sol-Vex nitrile by 8h. Safeskin showed a mean PROP mass permeated of 176+/-27 microg after 8h compared with a mean mass permeated for Sol-Vex of 3.17+/-4.08 microg. Thus, Sol-Vex was about 56 times more protective than Safeskin for an 8-h exposure. However, the kinetics of the permeation revealed that Safeskin can be worn for at least 200 min before disposal. When undiluted Comite challenged both types of nitrile, much faster permeation was observed. Safeskin gloves showed two steady state periods. The first had lag times (t(l)) values of about 1h, although normalized breakthrough times (t(b)) were gloves exposed continuously to undiluted Comite permeated above the normalized breakthrough threshold beyond 2.7h. A risk assessment revealed that the PROP skin permeation rate of 7.1 ng cm(-2)h(-1) was much slower than the first steady state Safeskin glove P(s) of 62,000 ng cm(-2)h(-1). Infrared analysis showed that the glove surfaces were not degraded by the Comite challenge. The chemically protective Sol-Vex gloves protected adequately against undiluted formulation for about 2.7h, whereas they provided protection for nearly 8h when the formulation was diluted with water to the highest concentration for field application. In contrast, the disposable Safeskin gloves did not protect at all for the undiluted formulation, but did for 200 min when the formulation was diluted with water to the highest

Study of skin model and geometry effects on thermal performance of thermal protective fabrics

Science.gov (United States)

Zhu, Fanglong; Ma, Suqin; Zhang, Weiyuan

2008-05-01

Thermal protective clothing has steadily improved over the years as new materials and improved designs have reached the market. A significant method that has brought these improvements to the fire service is the NFPA 1971 standard on structural fire fighters’ protective clothing. However, this testing often neglects the effects of cylindrical geometry on heat transmission in flame resistant fabrics. This paper deals with methods to develop cylindrical geometry testing apparatus incorporating novel skin bioheat transfer model to test flame resistant fabrics used in firefighting. Results show that fabrics which shrink during the test can have reduced thermal protective performance compared with the qualities measured with a planar geometry tester. Results of temperature differences between skin simulant sensors of planar and cylindrical tester are also compared. This test method provides a new technique to accurately and precisely characterize the thermal performance of thermal protective fabrics.

Radiation protection on nuclear medicine services

International Nuclear Information System (INIS)

Anon

2000-01-01

Nuclear medicine is a sector of the medicine that studies and applies radionuclide in diagnosis and therapy. Nuclear medicine is a very specific area of the medicine, making use of non-sealed radioactive sources which are prescribed to the patient orally or are injected. Special procedures in radiation protection are required in nuclear medicine to manipulate these kind of sources and to produce technetium-99m through molybdenum generator. The present paper addresses the them radiation protection in a Nuclear Medicine Department (NMD), showing the main requirements of the CNEN- National Commission of Nuclear Energy and the Public Health. Radiation protection procedures adopted in assembling a NMD, as well the daily techniques for monitoring and for individual dosimetry are discussed. Past and present analyses in a level of radiation protection are presented. (author)

Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study.

Science.gov (United States)

Hayward, Andrew C; Wang, Lili; Goonetilleke, Nilu; Fragaszy, Ellen B; Bermingham, Alison; Copas, Andrew; Dukes, Oliver; Millett, Elizabeth R C; Nazareth, Irwin; Nguyen-Van-Tam, Jonathan S; Watson, John M; Zambon, Maria; Johnson, Anne M; McMichael, Andrew J

2015-06-15

A high proportion of influenza infections are asymptomatic. Animal and human challenge studies and observational studies suggest T cells protect against disease among those infected, but the impact of T-cell immunity at the population level is unknown. To investigate whether naturally preexisting T-cell responses targeting highly conserved internal influenza proteins could provide cross-protective immunity against pandemic and seasonal influenza. We quantified influenza A(H3N2) virus-specific T cells in a population cohort during seasonal and pandemic periods between 2006 and 2010. Follow-up included paired serology, symptom reporting, and polymerase chain reaction (PCR) investigation of symptomatic cases. A total of 1,414 unvaccinated individuals had baseline T-cell measurements (1,703 participant observation sets). T-cell responses to A(H3N2) virus nucleoprotein (NP) dominated and strongly cross-reacted with A(H1N1)pdm09 NP (P < 0.001) in participants lacking antibody to A(H1N1)pdm09. Comparison of paired preseason and post-season sera (1,431 sets) showed 205 (14%) had evidence of infection based on fourfold influenza antibody titer rises. The presence of NP-specific T cells before exposure to virus correlated with less symptomatic, PCR-positive influenza A (overall adjusted odds ratio, 0.27; 95% confidence interval, 0.11-0.68; P = 0.005, during pandemic [P = 0.047] and seasonal [P = 0.049] periods). Protection was independent of baseline antibodies. Influenza-specific T-cell responses were detected in 43%, indicating a substantial population impact. Naturally occurring cross-protective T-cell immunity protects against symptomatic PCR-confirmed disease in those with evidence of infection and helps to explain why many infections do not cause symptoms. Vaccines stimulating T cells may provide important cross-protective immunity.

Natural T Cell–mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study

Science.gov (United States)

Wang, Lili; Goonetilleke, Nilu; Fragaszy, Ellen B.; Bermingham, Alison; Copas, Andrew; Dukes, Oliver; Millett, Elizabeth R. C.; Nazareth, Irwin; Nguyen-Van-Tam, Jonathan S.; Watson, John M.; Zambon, Maria; Johnson, Anne M.; McMichael, Andrew J.

2015-01-01

Rationale: A high proportion of influenza infections are asymptomatic. Animal and human challenge studies and observational studies suggest T cells protect against disease among those infected, but the impact of T-cell immunity at the population level is unknown. Objectives: To investigate whether naturally preexisting T-cell responses targeting highly conserved internal influenza proteins could provide cross-protective immunity against pandemic and seasonal influenza. Methods: We quantified influenza A(H3N2) virus–specific T cells in a population cohort during seasonal and pandemic periods between 2006 and 2010. Follow-up included paired serology, symptom reporting, and polymerase chain reaction (PCR) investigation of symptomatic cases. Measurements and Main Results: A total of 1,414 unvaccinated individuals had baseline T-cell measurements (1,703 participant observation sets). T-cell responses to A(H3N2) virus nucleoprotein (NP) dominated and strongly cross-reacted with A(H1N1)pdm09 NP (P < 0.001) in participants lacking antibody to A(H1N1)pdm09. Comparison of paired preseason and post-season sera (1,431 sets) showed 205 (14%) had evidence of infection based on fourfold influenza antibody titer rises. The presence of NP-specific T cells before exposure to virus correlated with less symptomatic, PCR-positive influenza A (overall adjusted odds ratio, 0.27; 95% confidence interval, 0.11–0.68; P = 0.005, during pandemic [P = 0.047] and seasonal [P = 0.049] periods). Protection was independent of baseline antibodies. Influenza-specific T-cell responses were detected in 43%, indicating a substantial population impact. Conclusions: Naturally occurring cross-protective T-cell immunity protects against symptomatic PCR-confirmed disease in those with evidence of infection and helps to explain why many infections do not cause symptoms. Vaccines stimulating T cells may provide important cross-protective immunity. PMID:25844934

Triphala, a formulation of traditional Ayurvedic medicine, shows

Indian Academy of Sciences (India)

Triphala, a formulation of traditional Ayurvedic medicine, shows protective effect against X-radiation in HeLa cells. YUKI TAKAUJI KENSUKE ... with the cellscultured in vitro. The simple bioassay system with human cultured cells would facilitate the understanding of themolecular basis for the beneficial effects of Triphala.

Experimental study of 2D scour and its protection at a rubble-mound breakwater

DEFF Research Database (Denmark)

Sumer, B. Mutlu; Fredsøe, Jørgen

2000-01-01

investigated for the following cases: (1) the protection apron with one layer of stones and (2) that with several layers of stones. The mechanism of slumping down of stones of the protection apron was also considered. The results of the toe protection study are given in the form of diagrams....

Intestinal mucus protects Giardia lamblia from killing by human milk.

Science.gov (United States)

Zenian, A J; Gillin, F D

1987-02-01

We have previously shown that nonimmune human milk kills Giardia lamblia trophozoites in vitro. Killing requires a bile salt and the activity of the milk bile salt-stimulated lipase. We now show that human small-intestinal mucus protects trophozoites from killing by milk. Parasite survival increased with mucus concentration, but protection was overcome during longer incubation times or with greater milk concentrations. Trophozoites preincubated with mucus and then washed were not protected. Protective activity was associated with non-mucin CsCl density gradient fractions. Moreover, it was heat-stable, non-dialyzable, and non-lipid. Whereas whole mucus inhibited milk lipolytic activity, protective mucus fractions did not inhibit the enzyme. Furthermore, mucus partially protected G. lamblia trophozoites against the toxicity of oleic acid, a fatty acid which is released from milk triglycerides by lipase. These studies show that mucus protects G. lamblia both by inhibiting lipase activity and by decreasing the toxicity of products of lipolysis. The ability of mucus to protect G. lamblia from toxic lipolytic products may help to promote intestinal colonization by this parasite.

Study of performance of acoustic fixture for using in noise reduction rate tests of hearing protection devices

Directory of Open Access Journals (Sweden)

zam Biabani

2016-06-01

Full Text Available Introduction:One of the recommended methods for evaluation effectiveness of hearing protection is use the acoustic fixture accordance with standard ISO 4869-3. The aim of this study was evaluate the acoustic performance of fixture for using in noise reduction rate tests of hearing protection devices in the laboratory. Methods: In this cross-sectional study , noise reduction rates of five common ear muffs used in the Iran industries were investigated based on the ISO 11904 standard, microphone in real ear method, using noise dosimeter (SVANTEK , Model SV102 equipped with microphone SV25 model which can install inside the ear on 30 subjects under laboratory conditions. Also, noise reduction rate of earmuffs was determined using the fixture model AVASINA9402 accordance with standard procedures. Data were analyzed using the software SPSS21. Results: The results showed the real noise reduction rates of the earmuffs on the studied subjects are from 59% to 94% nominal reduction rates. That rates for the ear muffs on the studied fixture are from 64% to 92.The results showed that the noise reduction rates of the ear muffs on subjects compared with and noise reduction rates of the ear muffs on fixture were not statistically significant (p> 0.05. Conclusion: The results showed the accuracy of noise reduction rate of earmuffs using the fixture compared with real subjects is acceptable. Hence, the fixture is good choice for environments where there’s no possibility of acoustic evaluation on real subjects, also for quality control of productions in the earmuff manufacturers.

Protection study of a diagnostic system for electron beam at the output of an accelerator

International Nuclear Information System (INIS)

Rahmani, Kaouther; Yaacoubi, Imen

2009-01-01

The aim of this work is the determination of the conception of a protection system dedicated to protect a diagnostic system in the CNSTN. According to this study, the suitable material for the protection against the electrons in the plexiglas and the supermalloy to protect the future diagnostic system against the magnetic field. (Author)

Aging assessment for active fire protection systems

International Nuclear Information System (INIS)

Ross, S.B.; Nowlen, S.P.; Tanaka, T.

1995-06-01

This study assessed the impact of aging on the performance and reliability of active fire protection systems including both fixed fire suppression and fixed fire detection systems. The experience base shows that most nuclear power plants have an aggressive maintenance and testing program and are finding degraded fire protection system components before a failure occurs. Also, from the data reviewed it is clear that the risk impact of fire protection system aging is low. However, it is assumed that a more aggressive maintenance and testing program involving preventive diagnostics may reduce the risk impact even further

Optimization of the radiation protection in industrial field: study of some practical cases

International Nuclear Information System (INIS)

Muglioni, P.

1998-01-01

Two situations are studied: the case of stationary gauges where the situation is sure with little actions to do to optimize the radiation protection and the case of mobile sources where the sources can submit to important exposure. In these conditions, the best way to optimize the radiation protection is to integrate the constraints, to put in operation a dosimetry and to keep a correct level of radiation protection information. (N.C.)

Protection Orders Protect Against Assault and Injury: A Longitudinal Study of Police-Involved Women Victims of Intimate Partner Violence

Science.gov (United States)

Kothari, Catherine L.; Rhodes, Karin V.; Wiley, James A.; Fink, Jeffrey; Overholt, Scott; Dichter, Melissa E.; Marcus, Steven C.; Cerulli, Catherine

2014-01-01

Objective To measure the efficacy of protection orders (POs) in reducing assault and injury-related outcomes using a matched comparison group and tracking outcomes over time. Methods This study was a retrospective review of police, emergency department, family court and prosecutor administrative records for a cohort of police-involved female IPV victims; all events over a four-year study period were abstracted. Victims who obtained protection orders (POs) were compared to a propensity-score-based match group without POs over three time periods: Before, during, and after the issuance of a PO. Results Having a PO in place was associated with significantly more calls to police for non-assaultive incidents, and more police charging requests that were multiple-count and felony-level. Comparing outcomes, PO victims had police incident rates that were more than double the matched group prior to the PO, but dropped to the level of the matched group during and after the order. ED visits dropped over time for both groups. Conclusion This study confirmed the protective effect of POs, which are associated with reduced police incidents and emergency department visits both during and after the order, and reduced police incidents compared to a matched comparison group. PMID:22491224

Hearing protection use in manufacturing workers: A qualitative study

Directory of Open Access Journals (Sweden)

Ravi K Reddy

2012-01-01

Full Text Available Occupational noise is a significant contributor to disabling hearing loss worldwide. Noise-induced hearing loss (NIHL has resulted in huge human and economic consequences costing New Zealand approximately $53M annually and rising. A high proportion of hearing loss claims are made by workers in the manufacturing sector. Hearing protection devices (HPDs are used together with engineering and administrative controls to minimize noise exposure and to prevent hearing loss. Unfortunately, inconsistent and improper use of HPDs has hindered efforts to prevent NIHL. The purpose of this study was to understand the factors that influence the use of HPDs amongst a group of manufacturing workers in New Zealand. A purposive sample of twenty-five workers was recruited to take part in semi-structured interviews. The open-ended questions were aimed at exploring the participants′ knowledge, attitude, beliefs, and behavior towards noise and HPDs. The data were analyzed using conventional content analysis and key themes emerged in relation to HPD use. Themes that emerged from the interviews either supported good hearing protection behavior or acted as barriers against it. Five major themes, (perception of noise, hearing preservation, reluctance to use HPDs, workplace interaction, and value of hearing and sub-themes described various factors that influence hearing protection use. Both personal and environmental factors influence the use of HPDs. Based on this study, personal and environmental factors need to be targeted for further research using ecological models to develop interventions that promote HPD use amongst workers.

Epidemiological and radio-biological studies in high background radiation areas of Kerala coast: implications in radiation protection science and human health

International Nuclear Information System (INIS)

Das, Birajalaxmi

2018-01-01

Till date, Linear No Threshold hypothesis (LNT) is well accepted in radiation protection science in spite of its limitations. However, dose response studies using multiple biological end points from high-background radiation areas have challenged the linearity. Radio-biological and epidemiological studies from high level natural radiation areas of Kerala coast showed non-linearity as well as efficient repair of DNA damage in HLNRA indicating that dose limits for public exposure needs to be revisited which may have implications in radiation protection science, human health and low dose radiation biology. However, further studies using high throughput approach is required to identify chronic radiation signatures in human population exposed to elevated level of natural background radiation

Fusion magnet safety studies program: superconducting magnet protection system and failure. Interim report

International Nuclear Information System (INIS)

Allinger, J.; Danby, G.; Hsieh, S.Y.; Keane, J.; Powell, J.; Prodell, A.

1975-11-01

This report includes the first two quarters study of available information on schemes for protecting superconducting magnets. These schemes can be divided into two different categories. The first category deals with the detection of faulty regions (or normal regions) in the magnet. The second category relates to the protection of the magnet when a fault is detected, and the derived signal which can be used to activate a safety system (or energy removal system). The general detection and protection methods are first described briefly and then followed by a survey of the protection systems used by different laboratories for various magnets. A survey of the cause of the magnet difficulties or failures is also included. A preliminary discussion of these protection schemes and the experimental development of this program is given

Feasibility study for core protection calculator development

International Nuclear Information System (INIS)

In, W. K.; Han, J. B.

2003-06-01

This project confirmed the development feasibility of new digital core protection system and established development plan for ITOPS that can replace the CPC system. The development plan and implementation strategy for ITOPS proposed in this project will be useful to successfully develop advanced digital core protection system for the CPC replacement in KSNP plants. YGN units 3 and 4 are expected to replace the CPC system within next ten years and the other KSNP plants are followed. The localization model for advanced digital core protection system, ITOPS, is judged to upgrade the Common Q CPC system in both system configuration and algorithm performance and can reduce the cost for supply and maintenance. Hence, ITOPS is expected to be installed in new Korea nuclear power plants and also useful to export the associated technology in the future

Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites.

Directory of Open Access Journals (Sweden)

Remko Schats

Full Text Available Sterile protection in >90% of volunteers against homologous Plasmodium falciparum infection has been achieved only using the controlled human malaria infection (CHMI model. This efficient model involves whole parasite immunizations under chloroquine prophylaxis (CPS-immunization, requiring only 30-45 mosquitoes bites infected with P. falciparum-sporozoites. Given the large diversity of P. falciparum parasites, it is essential to assess protection against heterologous parasite strains.In an open-label follow-up study, 16 volunteers previously CPS-immunized and challenged with P. falciparum NF54 (West-Africa in a dose de-escalation and challenge trial were re-challenged with clone NF135.C10 (Cambodia at 14 months after the last immunization (NCT01660854.Two out of thirteen NF54 protected volunteers previously fully protected against NF54 were also fully protected against NF135.C10, while 11/13 showed a delayed patency (median prepatent period of 10.5 days (range 9.0-15.5 versus 8.5 days in 5 malaria-naïve controls (p = 0.0005. Analysis of patency by qPCR indicated a 91 to >99% estimated reduction of liver parasite load in 7/11 partially protected subjects. Three volunteers previously not protected against NF54, were also not protected against NF135.C10.This study shows that CPS-immunization can induce heterologous protection for a period of more than one year, which is a further impetus for clinical development of whole parasite vaccines.Clinicaltrials.gov NCT01660854.

Insight from Molecular, Pathological, and Immunohistochemical Studies on Cellular and Humoral Mechanisms Responsible for Vaccine-Induced Protection of Rainbow Trout against Yersinia ruckeri

DEFF Research Database (Denmark)

Deshmukh, Sidhartha; Kania, Per W.; Chettri, Jiwan K.

2013-01-01

fish, whereas nonprotected fish still harbored bacteria for a week after infection. Vaccinated fish reestablished normal organ structure within a few days, whereas nonprotected fish showed abnormalities up to 1 month postinfection. Protection in the early phase of infection was mainly associated....... They comprised transformation of resident cells into macrophage-like cells and increased occurrence of CD8α and IgM cells, suggesting these cells as main players in protection. Future studies should investigate the causality between these factors and protection....

Protective Relay Studies for the Nigerian National Electric 330 KV ...

African Journals Online (AJOL)

The fundamental reasons for requiring these specific protective relaying features are also reviewed. Other protective relaying schemes that can accomplish the same basic protection objectives are presented. Based on the Nigerian special system characteristics, schemes to correct existing protection inadequacies are ...

Skin protection creams in medical settings: successful or evil?

Directory of Open Access Journals (Sweden)

Charlier Corinne

2008-07-01

Full Text Available Abstract Background Chronic exposure to mild irritants including cleansing and antiseptic products used for hand hygiene generates insults to the skin. To avoid unpleasant reactions, skin protection creams are commonly employed, but some fail to afford protection against a variety of xenobiotics. In this study, two skin protection creams were assayed comparatively looking for a protective effect if any against a liquid soap and an alcohol-based gel designed for hand hygiene in medical settings. Methods Corneosurfametry and corneoxenometry are two in vitro bioessays which were selected for their good reproducibility, sensitivity and ease of use. A Kruskal-Wallis ANOVA test followed by the Dunn test was realized to compare series of data obtained. Results Significant differences in efficacy were obtained between the two assayed skin protection creams. One of the two tested creams showed a real protective effect against mild irritants, but the other tested cream presented an irritant potential in its application with mild irritants. Conclusion The differences observed for the two tested skin protection creams were probably due to their galenic composition and their possible interactions with the offending products. As a result, the present in vitro bioassays showed contrasted effects of the creams corresponding to either a protective or an irritant effect on human stratum corneum.

Wolbachia-associated bacterial protection in the mosquito Aedes aegypti.

Directory of Open Access Journals (Sweden)

Yixin H Ye

Full Text Available BACKGROUND: Wolbachia infections confer protection for their insect hosts against a range of pathogens including bacteria, viruses, nematodes and the malaria parasite. A single mechanism that might explain this broad-based pathogen protection is immune priming, in which the presence of the symbiont upregulates the basal immune response, preparing the insect to defend against subsequent pathogen infection. A study that compared natural Wolbachia infections in Drosophila melanogaster with the mosquito vector Aedes aegypti artificially transinfected with the same strains has suggested that innate immune priming may only occur in recent host-Wolbachia associations. This same study also revealed that while immune priming may play a role in viral protection it cannot explain the entirety of the effect. METHODOLOGY/FINDINGS: Here we assess whether the level of innate immune priming induced by different Wolbachia strains in A. aegypti is correlated with the degree of protection conferred against bacterial pathogens. We show that Wolbachia strains wMel and wMelPop, currently being tested for field release for dengue biocontrol, differ in their protective abilities. The wMelPop strain provides stronger, more broad-based protection than wMel, and this is likely explained by both the higher induction of immune gene expression and the strain-specific activation of particular genes. We also show that Wolbachia densities themselves decline during pathogen infection, likely as a result of the immune induction. CONCLUSIONS/SIGNIFICANCE: This work shows a correlation between innate immune priming and bacterial protection phenotypes. The ability of the Toll pathway, melanisation and antimicrobial peptides to enhance viral protection or to provide the basis of malaria protection should be further explored in the context of this two-strain comparison. This work raises the questions of whether Wolbachia may improve the ability of wild mosquitoes to survive pathogen

A study on ship impacting a flexible crashworthy device for protecting bridge pier

Directory of Open Access Journals (Sweden)

Yang Liming

2015-01-01

Full Text Available As the accident of a vessel impacting a bridge pier will cause serious disaster, such as destroyed bridge, sinking ship and polluting environment, the technology and method to protect bridge pier from ship collision have been widely investigated recently. Due to the huge kinetic energy of large-tonnage ship and the short time duration in the collision, the studies involve impact mechanics. A developed flexible crashworthy device has been developed to protect bridges, which consists of an outer steel-periphery, an inner steel-periphery and the rubber coating SWRCs(soft elements installed between them. When the SWRC crashworthy device is installed, the collision duration under low impact force is prolonged due to its high compliance, which results in the ship having enough time to turn its navigation direction and most of the remainder kinetic energy being carried off by the turned away ship. Consequently, both impact forces on the ship and on the bridge pier decrease markedly. This is the key reason as to why the SWRC crashworthy device can avoid the destruction of both the bridge and the ship. Based on our results of theoretical studies and numerical simulations, the present paper will propose an experiment-adopted a real ship to impact a flexible crashworthy device. The collision test has been performed 12 times with different speed, carrying capacity, and impact angle of the ship. After the experiments, the ship, flexible crashworthy device and the pier are not damaged. The experiments show that the flexible crashworthy device can turn away the impact ship, so that the ship moves along the outer part of the device, which reduces the ship impact force on the bridge pier obviously. It not only protects bridges but also avoids the damage to ships.

The involvement of family in child protection cases in Iceland

Directory of Open Access Journals (Sweden)

Anni Haugen

2015-07-01

Full Text Available The aim of this study is to examine the involvement of families in child protection cases in Iceland, as well as to shed light on the attitudes of child protection workers on the importance of including families while working on child protection cases. The study is part of an international comparative analysis called: Social Work with Families: Social Workers’ Constructions of Family in Professional Practice. This article only addresses the Icelandic segment of the research. In the study, qualitative methods were used and three focus groups were conducted, in which the same three-step vignette about a child protection case was presented. The findings highlighted how difficult child protection workers found it to define the family. The main element is that family are those individuals closest to the child and connected to them through emotional ties, as Icelandic child protection workers seem to strive to involve family in child protection cases. However, there are signs which show that when working with more complicated cases the definition of a family becomes narrower, and involvement is restricted mostly to parents and grandparents. The findings also show that attitudes toward fathers differ from those toward mothers. The mother is expected to support and create security for the child, while the father is judged mostly on his violent behaviour and is not automatically regarded as providing support or actively taking responsibility for his child.

Financial consumer protection and customer satisfaction. A relationship study by using factor analysis and discriminant analysis

Directory of Open Access Journals (Sweden)

Marimuthu SELVAKUMAR

2015-11-01

Full Text Available This paper tries to make an attempt to study the relationship between the financial consumer protection and customer satisfaction by using factor analysis and discriminant analysis. The main objectives of the study are to analyze the financial consumer protection in commercial banks, to examine the customer satisfaction of commercial banks and to identify the factors of financial consumer protection lead customer satisfaction. There are many research work carried out on financial consumer protection in financial literacy, but the identification of factors which lead the financial consumer protection and the relationship between financial consumer protection and the customer satisfaction is very important, Particularly for banks to improve its quality and increase the customer satisfaction. Therefore this study is carried out with the aim of identifying the factors of financial consumer protection and its influence on customer satisfaction. This study is both descriptive and analytical in nature. It covers both primary and secondary data. The primary data has been collected from the customers of commercial banks using pre-tested interview schedule and the secondary data has been collected from standard books, journals, magazines, websites and so on.

Effectiveness of Human Research Protection Program Performance Measurements.

Science.gov (United States)

Tsan, Min-Fu; Nguyen, Yen

2017-10-01

We analyzed human research protection program performance metric data of all Department of Veterans Affairs research facilities obtained from 2010 to 2016. Among a total of 25 performance metrics, 21 (84%) showed improvement, four (16%) remained unchanged, and none deteriorated during the study period. The overall improvement from these 21 performance metrics was 81.1% ± 18.7% (mean ± SD), with a range of 30% to 100%. The four performance metrics that did not show improvement all had initial noncompliance/incidence rates of performance metrics that showed improvement ranged from 0.05% to 60%. However, of the 21 performance metrics that showed improvement, 10 had initial noncompliance/incidence rates of performance measurement is an effective tool in improving the performance of human research protection programs.

Studies on the protection effects of functional foods for skin immune system from radiation damage

International Nuclear Information System (INIS)

Yee, Sung Tae; Shin, Seong Hae; Kim, Do Sun; Heo, Ji Yun; Kang, Hye In

2007-07-01

We evaluated the protective effects of pilot products (HemoHIM and HemoTonic) on the UV-induced skin immune damages as the following. · Protective effects of HemoHIM and HemoTonic against UV using contact hypersensitivity model - Protection against depression of contact hypersensitivity by administration and skin application of HemoHIM and HemoTonic - Induction of dendritic cell differentiation and maturation by HemoHIM and HemoTonic treatment - Improvement of antigen-presenting activity of dedritic cells by HemoHIM and HemoTonic treatment · Protective effects of HemoHIM and HemoTonic on skin immune system against UV-irradiation - Protection of antigen-presenting activity of dendritic cells under UV-irradiation - In vivo protection of antigen-presenting activity of Langerhans cells in UV-irradiated mice · Protective effects of HemoHIM on UV-induced apoptosis of dendritic cells - Inhibition of cell membrane change, mitochondrial potential change, SubG1 cell population, nuclear condensation, and DNA fragmentation in UV-irradiated dendritic cells · Anti-allergic effects of HemoHIM and HemoTonic in human adipocyte HMC-1 cells - Inhibition of allergic histamine release from adipocytes - Inhibition of secretion of inflammatory cytokines (IL-6, IL-8, TNF-α, GM-CSF) - Inhibition of c-kit, tryptase, FcεRI mRNA expression From these results, the developed functional food products (HemoHIM, HemoTonic) showed the protection and recovery of the immune functions in the UV-irradiated skin. It is suggested that these products may be used as a new functional food or cosmetic material for the protection of skin damage and the promotion of recovery

The protective role of self-efficacy against workplace incivility and burnout in nursing: A time-lagged study.

Science.gov (United States)

Fida, Roberta; Laschinger, Heather K Spence; Leiter, Michael P

Incivility has negative consequences in the workplace and remains a prevalent issue in nursing. Research has consistently linked incivility to nurse burnout and, in turn, to poor mental health and turnover intentions. To retain high-quality nurses, it is important to understand what factors might protect nurses from the negative effects of workplace mistreatment. The aim of the study was to investigate the role of relational occupational coping self-efficacy in protecting nurses from workplace incivility and related burnout and turnover intentions. A two-wave national sample of 596 Canadian nurses completed mail surveys both at Time 1 and one year later at Time 2. Structural equation modeling was used to test the hypothesized model. The model showed a good fit, and most of the hypothesized paths were significant. Overall, the results supported the hypothesized protective effect of relational occupational coping self-efficacy against incivility and later burnout, mental health, and turnover intentions. Relational occupational coping self-efficacy is an important protective factor against negative work behavior. Organizations should provide nurses with opportunities to build their coping strategies for managing job demands and difficult interpersonal interactions. Similarly, providing exposure to effective role models and providing meaningful verbal encouragement are other sources of efficacy information for building nurses' relational coping self-efficacy.

Assessment of radiation protection practices among radiographers in Lagos, Nigeria.

Science.gov (United States)

Eze, Cletus Uche; Abonyi, Livinus Chibuzo; Njoku, Jerome; Irurhe, Nicholas Kayode; Olowu, Oluwabola

2013-11-01

Use of ionising radiation in diagnostic radiography could lead to hazards such as somatic and genetic damages. Compliance to safe work and radiation protection practices could mitigate such risks. The aim of the study was to assess the knowledge and radiation protection practices among radiographers in Lagos, Nigeria. The study was a prospective cross sectional survey. Convenience sampling technique was used to select four x-ray diagnostic centres in four tertiary hospitals in Lagos metropolis. Data were analysed with Epi- info software, version 3.5.1. Average score on assessment of knowledge was 73%. Most modern radiation protection instruments were lacking in all the centres studied. Application of shielding devices such as gonad shield for protection was neglected mostly in government hospitals. Most x-ray machines were quite old and evidence of quality assurance tests performed on such machines were lacking. Radiographers within Lagos metropolis showed an excellent knowledge of radiation protection within the study period. Adherence to radiation protection practices among radiographers in Lagos metropolis during the period studied was, however, poor. Radiographers in Lagos, Nigeria should embrace current trends in radiation protection and make more concerted efforts to apply their knowledge in protecting themselves and patients from harmful effects of ionising radiation.

A Study of Distributed Generation System Characteristics and Protective Load Control Strategy

DEFF Research Database (Denmark)

Wei, Mu; Chen, Zhe

2011-01-01

Due to the smaller inertia feature of a Wind Turbine (WT) involved Distributed Generation System (DGS), the WT’s induction generator are more vulnerable to frequency and voltage disturbances. Therefore the study investigates the DGS characteristics respectively from power plants, i.e. WTs and load....... Two kinds of wind turbines: Doubly-fed Induction Generator (DFIG) and Fixed-speed Wind Turbine (FSWT) are compared in this study. A conventional power system protective scheme may not response promptly, which could lead an undesired disconnection of WTs for the turbine protection purpose. Consequently...

Radiation transformation studies: are they relevant to radiation protection problems?

International Nuclear Information System (INIS)

Seymour, C.B.; Mothersill, C.

1988-01-01

Because of the difficulties of studying radio-carcinogenesis in humans, several in vitro systems are utilised. These cell transformation systems are reviewed, with particular emphasis on their relevance to human radiological protection problems. Most available systems use rodent fibroblasts. These are discussed in detail. Attention is drawn to certain artefacts which can cause problems with interpretation of such data. The relevance of these systems is questionable because of species differences, particularly concerning life span and because most human tumours are derived from epithelial cells. New epithelial culture systems and three-dimensional tissue culture methods becoming available are discussed in the light of their potential for addressing radiation protection problems. (author)

Protective interest rate as tax instrument of corporate capital protection

Directory of Open Access Journals (Sweden)

Vukašinović Jovan

2015-01-01

Full Text Available This paper deals with researching negative consequences of allocation of economic (virtual gains made as a result of conventional accounting concept by facing current income with historical expenses and necessity to promote additional stimulating instruments that are at disposal by the state in order to eliminate these negative consequences. one of them is certainly protective interest as a relatively new active fiscal instrument of capital protection and recognition of price of invested owner's equity in business ventures, i.e. a specific form of compensation by the state for invested capital bearing in mind, that no source is free, including ones own sources. We also showed mechanisms of protective interest which, together with other measures of macroeconomic policy, should contribute to the protection of real purchasing power of company equity and increase of net gain, left on company's disposal for new investments, new work places, more money in the budget, protection of actual assets against taxing in the conditions of inflation, etc.

Modelling of protective actions in the German Risk Study (FRG)

International Nuclear Information System (INIS)

Burkart, A.K.

1981-01-01

An emergency response model for nuclear accidents has to allow for a great number of widely different emergency conditions. In addition, it should be compatible with the pertinent laws, regulations, ordinances, guidelines, criteria and reference levels. The German (FRG) guidelines are basic and flexible rather than precise, many decisions being left to the emergency management. In the Risk Study these decisions had to be anticipated. After a brief discussion of the basis of the emergency response model employed in the German Risk Study (FRG), the essential requirements to be met are listed. The main part of the paper deals with the rationale and specification of protective actions. As a result of the calculations the numbers of persons and sizes of areas involved in protective actions are presented. The last section deals with the variation of input data. (author)

Radiation protection to the eye and thyroid during diagnostic cerebral angiography: a phantom study.

LENUS (Irish Health Repository)

Shortt, C P

2008-08-01

We measured radiation doses to the eye and thyroid during diagnostic cerebral angiography to assess the effectiveness of bismuth and lead shields at dose reduction. Phantom head angiographic studies were performed with bismuth (study 1) and lead shields (study 2). In study 1 (12 phantoms), thermoluminescent dosimeters (TLD) were placed over the eyes and thyroid in three groups: (i) no shields (four phantoms); (ii) anterior bismuth shields (four phantoms) and (iii) anterior and posterior bismuth shields (four phantoms). In a second study (eight phantoms), lead shields were placed over the thyroid only and TLD dose measurements obtained in two groups: (i) no shielding (four phantoms) and (ii) thyroid lead shielding (four phantoms). A standard 4-vessel cerebral angiogram was performed on each phantom. Study 1 (bismuth shields) showed higher doses to the eyes compared with thyroid (mean 13.03 vs 5.98 mSv, P < 0.001) and a higher eye dose on the X-ray tube side. Overall, the use of bismuth shielding did not significantly reduce dose to either eyes or thyroid in the measured TLD positions. In study 2, a significant thyroid dose reduction was found with the use of lead shields (47%, mean 2.46 vs 4.62 mSv, P < 0.001). Considerable doses to the eyes and thyroid highlight the need for increased awareness of patient protection. Eye shielding is impractical and interferes with diagnostic capability. Thyroid lead shielding yields significant protection to the thyroid, is not in the field of view and should be used routinely.

Radiation protection to the eye and thyroid during diagnostic cerebral angiography : a phantom study

International Nuclear Information System (INIS)

Shortt, C. P.; Malone, L.; Thornton, J.; Brennan, P.; Lee, M. J.

2008-01-01

Full text: We measured radiation doses to the eye and thyroid during diagnostic cerebral angiography to assess the effectiveness of bismuth and lead shields at dose reduction. Phantom head angiographic studies were performed with bismuth (study 1) and lead shields (study 2). In study 1 (12 phantoms), thermoluminescent dosimeters (TLD) were placed over the eyes and thyroid in three groups: (i) no shields (four phantoms); (ii) anterior bismuth shields (four phantoms) and (iii) anterior and posterior bismuth shields (four phantoms). In a second study (eight phantoms), lead shields were placed over the thyroid only and TLD dose measurements obtained in two groups: (i) no shielding (four phantoms) and (ii) thyroid lead shielding (four phantoms). A standard 4-vessel cerebral angiogram was performed on each phantom. Study 1 (bismuth shields) showed higher doses to the eyes compared with thyroid (mean 13.03 vs 5.98 mSv, P < 0.001) and a higher eye dose on the X-ray tube side. Overall, the use of bismuth shielding did not significantly reduce dose to either eyes or thyroid in the measured TLD positions. In study 2, a significant thyroid dose reduction was found with the use of lead shields (47%, mean 2.46 vs 4.62 mSv, P < 0.001). Considerable doses to the eyes and thyroid highlight the need for increased awareness of patient protection. Eye shielding is impractical and interferes with diagnostic capability. Thyroid lead shielding yields significant protection to the thyroid, is not in the field of view and should be used routinely.

Protected Areas

Data.gov (United States)

Kansas Data Access and Support Center — This dataset shows the boundaries of properties in Kansas in public or institutional ownership that contain ecological resources that merit some level of protection....

ASSESSING ANGELS IN THE NURSERY: A PILOT STUDY OF CHILDHOOD MEMORIES OF BENEVOLENT CAREGIVING AS PROTECTIVE INFLUENCES.

Science.gov (United States)

Narayan, Angela J; Ippen, Chandra Ghosh; Harris, William W; Lieberman, Alicia F

2017-07-01

This pilot study provides the first empirical test of the concept of "Angels in the Nursery" by examining whether childhood memories of benevolent caregiving experiences protect against heightened levels of psychopathology in high-risk mothers. The study hypothesized that (a) elaborated childhood memories of feeling loved by a caregiver ("angel memories") would moderate adulthood posttraumatic stress disorder (PTSD) symptoms in mothers with childhood maltreatment histories, and (b) spontaneous traumatic intrusions ("ghost memories") would mediate childhood maltreatment and adulthood PTSD symptoms. Participants were 54 mothers (M = 32.79 years, SD = 8.91; 59.2% African American, 13.0% Caucasian, 5.6% Latina, 22.2% biracial/multiracial) who completed standardized assessments of childhood maltreatment and adulthood PTSD symptoms, and a novel instrument, the Angels in the Nursery Interview ("Angels Interview," Van Horn, Lieberman, & Harris, 2008). Results showed that angel memories significantly moderated childhood maltreatment and adulthood PTSD symptoms, consistent with a protective effect. Higher levels of ghost memories during the Angels Interview were significantly associated with more extensive childhood maltreatment, but did not mediate maltreatment and PTSD symptoms. Findings indicate that the Angels Interview can identify pathogenic intrusions rooted in childhood maltreatment and protective factors to promote maternal mental health and buffer the intergenerational transmission of trauma. © 2017 Michigan Association for Infant Mental Health.

Radiation protection at urological fluoroscopy working stations

International Nuclear Information System (INIS)

Forster, D.; Mohr, H.

1979-01-01

Two newly developed radiation protection devices for urological working stations are presented. The local dose to which doctor and assisting personnel are exposed during fluoroscopy and radiography was measured and the radiation burden with and without radiation protection determined. The studies show that without these devices organs such as the eyes are exposed, at a normal working distance from the table, to such an amount of scattered radiation as to reduce the permitted number of examinations per week. (Auth.)

Study on generic intervention levels for protecting the public in a nuclear accident or radiological emergency

International Nuclear Information System (INIS)

Suzuki, Fabio Fumio

2003-01-01

After a nuclear accident or radiological emergency, several social and economical factors shall be considered for the actions to protect the public and to recover the environment. The application of the radiological protection principles on practices in intervention situations may lead to adoption of protective measures disproportional to the involved risk, compromising the resources available to more effective actions. This causes a negative impact on the population and may conduct to discredit about the protective measures and the lost of confidence on the authorities. In this context, the principles of radiological protection for interventions should be studied and analyzed for being adequately applied in accident situations or radiological emergencies that involves the country. These principles are constantly improved and the concept of generic intervention level plays an important role in the decision-making to protect the public. The costs involved to the protective measures for the public in Brazil were studied and cost benefit analysis techniques were applied to estimate the generic intervention levels for public protection applicable in the country. These results were compared to those values internationally recommended, as well to values obtained in a similar study accomplished for Japan. It was also performed a sensibility analysis of the results regarding a value and a simple analysis of the results considering the costs of the several protective measures. (author)

Development of a safe ultraviolet camera system to enhance awareness by showing effects of UV radiation and UV protection of the skin (Conference Presentation)

Science.gov (United States)

Verdaasdonk, Rudolf M.; Wedzinga, Rosaline; van Montfrans, Bibi; Stok, Mirte; Klaessens, John; van der Veen, Albert

2016-03-01

The significant increase of skin cancer occurring in the western world is attributed to longer sun expose during leisure time. For prevention, people should become aware of the risks of UV light exposure by showing skin damage and the protective effect of sunscreen with an UV camera. An UV awareness imaging system optimized for 365 nm (UV-A) was develop using consumer components being interactive, safe and mobile. A Sony NEX5t camera was adapted to full spectral range. In addition, UV transparent lenses and filters were selected based on spectral characteristics measured (Schott S8612 and Hoya U-340 filters) to obtain the highest contrast for e.g. melanin spots and wrinkles on the skin. For uniform UV illumination, 2 facial tanner units were adapted with UV 365 nm black light fluorescent tubes. Safety of the UV illumination was determined relative to the sun and with absolute irradiance measurements at the working distance. A maximum exposure time over 15 minutes was calculate according the international safety standards. The UV camera was successfully demonstrated during the Dutch National Skin Cancer day and was well received by dermatologists and participating public. Especially, the 'black paint' effect putting sun screen on the face was dramatic and contributed to the awareness of regions on the face what are likely to be missed applying sunscreen. The UV imaging system shows to be promising for diagnostics and clinical studies in dermatology and potentially in other areas (dentistry and ophthalmology)

Photolabile protection for amino acids: studies on the release from novel benzoquinolone cages.

Science.gov (United States)

Fonseca, Andrea S C; Soares, Ana M S; Gonçalves, M Sameiro T; Costa, Susana P G

2015-12-01

The synthesis of a novel fused nitrogen heterocycle, benzoquinolone, for evaluation as a photocleavable protecting group is described for the first time by coupling to model amino acids (alanine, phenylalanine and glutamic acid). Conversion of the phenylalanine ester conjugate to the thionated derivative was accomplished by reaction with Lawesson's reagent. Photocleavage studies of the carbonyl and thiocarbonyl benzoquinolone conjugates in various solvents and at different wavelengths (300, 350 and 419 nm) showed that the most interesting result was obtained at 419 nm for the thioconjugate, revealing that the presence of the thiocarbonyl group clearly improved the photolysis rates, giving practicable irradiations times for the release of the amino acids (less than 1 min).

Radiological Protection and Nuclear Engineering Studies in Multi-MW Target Systems

Science.gov (United States)

Luis, Raul Fernandes

goal of this work was to perform an optimisation study for the ISOLDE neutron converter and Vssion target system. The target system was simulated using FLUKA and the cross section codes TALYS and ABRABLA, with the objective of maximising the performance of the system for the production of pure beams of neutron-rich isotopes, suppressing the contaminations by undesired neutron-deficient isobars. Two alternative target systems were proposed in the optimisation studies; the simplest of the two, with some modiVcations, was built as a prototype and tested at ISOLDE. The experimental results clearly show that it is possible, with simple changes in the layouts of the target systems, to produce purer beams of neutron-rich isotopes around the doubly magic nuclei 78Ni and 132Sn. A study of Radiological Protection was also performed, comparing the performances of the prototype target system and the standard ISOLDE target system. None

Studies on the protection effects of functional foods for skin immune system from radiation damage

Energy Technology Data Exchange (ETDEWEB)

Yee, Sung Tae; Shin, Seong Hae; Kim, Do Sun; Heo, Ji Yun; Kang, Hye In [Sunchon National University, Sunchon (Korea, Republic of)

2007-07-15

We evaluated the protective effects of pilot products (HemoHIM and HemoTonic) on the UV-induced skin immune damages as the following. centre dot Protective effects of HemoHIM and HemoTonic against UV using contact hypersensitivity model - Protection against depression of contact hypersensitivity by administration and skin application of HemoHIM and HemoTonic - Induction of dendritic cell differentiation and maturation by HemoHIM and HemoTonic treatment - Improvement of antigen-presenting activity of dedritic cells by HemoHIM and HemoTonic treatment centre dot Protective effects of HemoHIM and HemoTonic on skin immune system against UV-irradiation - Protection of antigen-presenting activity of dendritic cells under UV-irradiation - In vivo protection of antigen-presenting activity of Langerhans cells in UV-irradiated mice centre dot Protective effects of HemoHIM on UV-induced apoptosis of dendritic cells - Inhibition of cell membrane change, mitochondrial potential change, SubG1 cell population, nuclear condensation, and DNA fragmentation in UV-irradiated dendritic cells centre dot Anti-allergic effects of HemoHIM and HemoTonic in human adipocyte HMC-1 cells - Inhibition of allergic histamine release from adipocytes - Inhibition of secretion of inflammatory cytokines (IL-6, IL-8, TNF-alpha, GM-CSF) - Inhibition of c-kit, tryptase, FcepsilonRI mRNA expression From these results, the developed functional food products (HemoHIM, HemoTonic) showed the protection and recovery of the immune functions in the UV-irradiated skin. It is suggested that these products may be used as a new functional food or cosmetic material for the protection of skin damage and the promotion of recovery

Ethics and data protection in human biomarker studies in environmental health.

Science.gov (United States)

Casteleyn, Ludwine; Dumez, Birgit; Van Damme, Karel; Anwar, Wagida A

2013-08-01

Human biomarker studies in environmental health are essential tools to study the relationship between health and environment. They should ultimately contribute to a better understanding of environmentally induced adverse health effects and to appropriate preventive actions. To ensure the protection of the rights and dignity of study participants a complex legal and ethical framework is applied, consisting of several international directives, conventions, and guidelines, whether or not translated in domestic laws. Main characteristics of ethics and data protection in studies using biomarkers in the field of environmental health are summarized and current discussions on related questions and bottlenecks highlighted. In the current regulatory context, dominated by the protection of the individual study participant, difficulties are reported due to the different interpretation and implementation of the regulations of concern within and across borders. Advancement of consistency and compatibility is recommended and efforts are ongoing. An increasing demand for secondary use of data and samples poses additional challenges in finding a right balance between the individual rights of the study participants on the one hand and the common interest of, and potential benefit for the public or community at large on the other. Ethics committees could play a key role in assessing problems originating from the sometimes competing needs at individual and societal level. Building trust in science amongst (potential) study participants and within the community allows the inclusion of arguments from the societal perspective. This requires increased attention for respectful communication efforts. Striving for public participation in decision making processes may promote policy relevant research and the related translation of study results into action. Copyright © 2013 Elsevier GmbH. All rights reserved.

Predictors of sun protection behaviors and severe sunburn in an international online study.

Science.gov (United States)

Bränström, Richard; Kasparian, Nadine A; Chang, Yu-mei; Affleck, Paul; Tibben, Aad; Aspinwall, Lisa G; Azizi, Esther; Baron-Epel, Orna; Battistuzzi, Linda; Bergman, Wilma; Bruno, William; Chan, May; Cuellar, Francisco; Debniak, Tadeusz; Pjanova, Dace; Ertmanski, Slawomir; Figl, Adina; Gonzalez, Melinda; Hayward, Nicholas K; Hocevar, Marko; Kanetsky, Peter A; Leachman, Sancy A; Heisele, Olita; Palmer, Jane; Peric, Barbara; Puig, Susana; Schadendorf, Dirk; Gruis, Nelleke A; Newton-Bishop, Julia; Brandberg, Yvonne

2010-09-01

The incidence of melanoma continues to increase in many countries, and primary prevention of melanoma includes avoidance of sunburn as well as adequate sun protection behavior. The aim of this study was to examine the prevalence of self-reported sun protection behaviors and sunburn in users of the Internet, and to identify the demographic, clinical, and attitudinal/motivational correlates of sun protection behaviors. Self-report data were gathered on behalf of the GenoMEL consortium using an online survey available in 10 different languages, and 8,178 individuals successfully completed at least 80% of survey items, with 73% of respondents from Europe, 12% from Australia, 7% from the United States, 2% from Israel, and 6% from other countries. Half of all respondents and 27% of those with a previous melanoma reported at least one severe sunburn during the previous 12 months. The strongest factors associated with sun protection behavior were perceived barriers to protection (beta = -0.44/beta = -0.37), and respondents who reported a positive attitude toward suntans were less likely to protect (beta = -0.16/beta = -0.14). Reported use of protective clothing and shade, as well as avoidance of midday sun exposure, were more strongly related to reduced risk of sunburn than sunscreen use. Despite widespread dissemination of public health messages about the importance of sun protection, a substantial proportion of this international sample, including respondents with a previous melanoma, reported inadequate sun protection behaviors resulting in severe sunburn. Future strategies to decrease sunburn should target the practical, social, and psychological barriers associated with nonuptake of sun protection. (c)2010 AACR.

Predictors of Sun Protection Behaviours and Severe Sunburn inan International on-line study

Science.gov (United States)

Bränström, Richard; Kasparian, Nadine A.; Chang, Yu-mei; Affleck, Paul; Tibben, Aad; Aspinwall, Lisa G.; Azizi, Esther; Baron-Epel, Orna; Battistuzzi, Linda; Bergman, Wilma; Bruno, William; Chan, May; Cuellar, Francisco; Dębniak, Tadeusz; Pjanova, Dace; Ertmański, Sƚawomir; Figl, Adina; Gonzalez, Melinda; Hayward, Nicholas K.; Hocevar, Marko; Kanetsky, Peter A.; Leachman, Sancy A.; Heisele, Olita; Palmer, Jane; Peric, Barbara; Puig, Susana; Schadendorf, Dirk; Gruis, Nelleke A.; Newton-Bishop, Julia; Brandberg, Yvonne

2013-01-01

Background The incidence of melanoma continues to increase in many countries, and primary prevention of melanoma includes avoidance of sunburn as well as adequate sun protection behaviour. The aim of this study was to examine the prevalence of self-reported sun protection behaviours and sunburn in users of the Internet, and to identify the demographic, clinical and attitudinal/motivational correlates of sun protection behaviours. Methods Self-report data were gathered on behalf of GenoMEL (www.genomel.org) using an online survey available in 10 different languages, and 8,178 individuals successfully completed at least 80% of survey items, with 73% of respondents from Europe, 12% from Australia, 7% from the USA, 2% from Israel, and 6% from other countries. Results Half of all respondents and 27% of those with a previous melanoma reported at least one severe sunburn during the previous 12 months. The strongest factors associated with sun protection behaviour were perceived barriers to protection (β=−0.44/β=−0.37), and respondents who reported a positive attitude towards suntans were less likely to protect (β=−0.16/β=−0.14). Reported use of protective clothing and shade, as well as avoidance of midday sun exposure, were more strongly related to reduced risk of sunburn than sunscreen use. Conclusions Despite widespread dissemination of public health messages about the importance of sun protection, a substantial proportion of this international sample, including respondents with a previous melanoma, reported inadequate sun protection behaviours resulting in severe sunburn. Impact Future strategies to decrease sunburn should target the practical, social and psychological barriers associated with non-uptake of sun protection. PMID:20643826

Phytoceramide Shows Neuroprotection and Ameliorates Scopolamine-Induced Memory Impairment

Directory of Open Access Journals (Sweden)

Seikwan Oh

2011-10-01

Full Text Available The function and the role phytoceramide (PCER and phytosphingosine (PSO in the central nervous system has not been well studied. This study was aimed at investigating the possible roles of PCER and PSO in glutamate-induced neurotoxicity in cultured neuronal cells and memory function in mice. Phytoceramide showed neuro-protective activity in the glutamate-induced toxicity in cultured cortical neuronal cells. Neither phytosphingosine nor tetraacetylphytosphingosine (TAPS showed neuroproective effects in neuronal cells. PCER (50 mg/kg, p.o. recovered the scopolamine-induced reduction in step-through latency in the passive avoidance test; however, PSO did not modulate memory function on this task. The ameliorating effects of PCER on spatial memory were confirmed by the Morris water maze test. In conclusion, through behavioral and neurochemical experimental results, it was demonstrated that central administration of PCER produces amelioration of memory impairment. These results suggest that PCER plays an important role in neuroprotection and memory enhancement and PCER could be a potential new therapeutic agent for the treatment of neurodegenerative diseases such as Alzheimer’s disease.

Predicting sun protection behaviors using protection motivation variables.

Science.gov (United States)

Ch'ng, Joanne W M; Glendon, A Ian

2014-04-01

Protection motivation theory components were used to predict sun protection behaviors (SPBs) using four outcome measures: typical reported behaviors, previous reported behaviors, current sunscreen use as determined by interview, and current observed behaviors (clothing worn) to control for common method bias. Sampled from two SE Queensland public beaches during summer, 199 participants aged 18-29 years completed a questionnaire measuring perceived severity, perceived vulnerability, response efficacy, response costs, and protection motivation (PM). Personal perceived risk (similar to threat appraisal) and response likelihood (similar to coping appraisal) were derived from their respective PM components. Protection motivation predicted all four SPB criterion variables. Personal perceived risk and response likelihood predicted protection motivation. Protection motivation completely mediated the effect of response likelihood on all four criterion variables. Alternative models are considered. Strengths and limitations of the study are outlined and suggestions made for future research.

Studies on the transfer of protective immunity with lymphoid cells from mice immune to malaria sporozoites

International Nuclear Information System (INIS)

Verhave, J.P.; Strickland, G.T.; Jaffe, H.A.; Ahmed, A.

1978-01-01

In an effort to understand the mechanisms involved in the protective immunity to malarial sporozoites, an A/J mouse/Plasmodium berghei model was studied. Protective immunity could consistently be adoptively transferred only by using sublethal irradiation of recipients (500 R); a spleen equivalent (100 x 10 6 ) of donor cells from immune syngeneic mice; and a small booster immunization (1 x 10 4 ) of recipients with irradiation-attenuated sporozoites. Recipient animals treated in this manner were protected from lethal challenge with 1 x 10 4 nonattenuated sporozoites. Immune and nonimmune serum and spleen cells from nonimmune animals did not protect recipient mice. Fewer immune spleen cells (50 x 10 6 ) protected some recipients. In vitro treatment of immune spleen cells with anti-theta sera and complement abolished their ability to transfer protection. This preliminary study suggests that protective sporozoite immunity can be transferred with cells, and that it is T cell dependent

Study on dinamic behavior and least burying depth of underground protective pipe

Energy Technology Data Exchange (ETDEWEB)

Kataoka, Tetsuyuki; Kokusyo, Goji; Tanaka, Yukihisa; Kobayashi, Seiichi

1988-03-30

Effect of unit load per travel wheel on the protective pipe was studied when electricity cable distribution lines were buried in the depth less than the present standard for electric equipment, and logical burying depth was investigated. Test items were material test of the protective pipe, indoor load test, and field test at loamy ground. Impact resistance hard PVC pipe was used as the protective pipe, and its strength and elastic modulus were measured. Along with these tests, it was confirmed that there was no problem of cracking by repeated flattening or breakage by fatigue. By indoor test, it was observed that, in case of shallow burying, creap deformation was small, stress concentrate occured at the middle of axial direction, and that flattening ratio was seriously affected by the method of backfilling. Field test was conducted by applying the static load of a 20 ton dump truck, and the deformation, stress, and subsidence of the protective pipe, were measured. As the conclusion of those experiments, it was found that burying of protective pipe in the depth of not less than 30 cm is allowable, as long as sufficient bakfilling is made. (14 figs, 3 tabs, 3 refs)

Summary of Building Protection Factor Studies for External Exposure to Ionizing Radiation

Energy Technology Data Exchange (ETDEWEB)

Dillon, Michael B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kane, Jave [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Nasstrom, John [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Homann, Steve [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pobanz, Brenda [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2016-02-17

Radiation dose assessments are used to help inform decisions to minimize health risks in the event of an atmospheric release of radioactivity including, for example, from a Radiological Dispersal Device, an Improvised Nuclear Device detonation, or a Nuclear Power Plant accident. During these incidents, radiation dose assessments for both indoor and outdoor populations are needed to make informed decisions. These dose assessments inform emergency plans and decisions including, for example, identifying areas in which people should be sheltered and determining when controlled population evacuations should be made. US dose assessment methodologies allow consideration of the protection, and therefore dose reduction, that buildings provide their occupants. However, these methodologies require an understanding of the protection provided by various building types that is currently lacking. To help address this need, Lawrence Livermore National Laboratory, in cooperation with Sandia National Laboratories and the Nuclear Regulatory Commission, was tasked with (a) identifying prior building protection studies, (b) extracting results relevant to US building construction, and (c) summarizing building protection by building type. This report focuses primarily on the protection against radiation from outdoor fallout particles (external gamma radiation).

Summary of Building Protection Factor Studies for External Exposure to Ionizing Radiation

International Nuclear Information System (INIS)

Dillon, Michael B.; Kane, Jave; Nasstrom, John; Homann, Steve; Pobanz, Brenda

2016-01-01

Radiation dose assessments are used to help inform decisions to minimize health risks in the event of an atmospheric release of radioactivity including, for example, from a Radiological Dispersal Device, an Improvised Nuclear Device detonation, or a Nuclear Power Plant accident. During these incidents, radiation dose assessments for both indoor and outdoor populations are needed to make informed decisions. These dose assessments inform emergency plans and decisions including, for example, identifying areas in which people should be sheltered and determining when controlled population evacuations should be made. US dose assessment methodologies allow consideration of the protection, and therefore dose reduction, that buildings provide their occupants. However, these methodologies require an understanding of the protection provided by various building types that is currently lacking. To help address this need, Lawrence Livermore National Laboratory, in cooperation with Sandia National Laboratories and the Nuclear Regulatory Commission, was tasked with (a) identifying prior building protection studies, (b) extracting results relevant to US building construction, and (c) summarizing building protection by building type. This report focuses primarily on the protection against radiation from outdoor fallout particles (external gamma radiation).

Analytic study for physical protection system (PPS) in nuclear power plants (NPPs)

Energy Technology Data Exchange (ETDEWEB)

Woo, Tae Ho, E-mail: thw@snu.ac.kr

2013-12-15

Highlights: • The physical protection system (PPS) is investigated. • General NPPs are modeled in the study. • Possible terror cases, likelihood, and consequence are studied. • PPS is constructed by analytical methods. - Abstract: The nuclear safeguard is analyzed in the aspect of the physical protection system (PPS) in nuclear power plants (NPPs). The PPS is reviewed and its related terror scenarios are investigated. The PPS is developed using analytical methods. In the terror scenarios, there are 8 possible cases for the terror attacks to the NPPs. Then, the likelihood of terror is classified by the general terror incidents. The consequence of terror is classified by Design Basis Threat (DBT) of the International Atomic Energy Agency (IAEA) scale. The physical protection method is suggested by defense-in-depth constraints and severe accident countermeasures. Finally, the advanced PPS is constructed, which could be used for the preparation for the possible terror attacks in the NPPs.

Analytic study for physical protection system (PPS) in nuclear power plants (NPPs)

International Nuclear Information System (INIS)

Woo, Tae Ho

2013-01-01

Highlights: • The physical protection system (PPS) is investigated. • General NPPs are modeled in the study. • Possible terror cases, likelihood, and consequence are studied. • PPS is constructed by analytical methods. - Abstract: The nuclear safeguard is analyzed in the aspect of the physical protection system (PPS) in nuclear power plants (NPPs). The PPS is reviewed and its related terror scenarios are investigated. The PPS is developed using analytical methods. In the terror scenarios, there are 8 possible cases for the terror attacks to the NPPs. Then, the likelihood of terror is classified by the general terror incidents. The consequence of terror is classified by Design Basis Threat (DBT) of the International Atomic Energy Agency (IAEA) scale. The physical protection method is suggested by defense-in-depth constraints and severe accident countermeasures. Finally, the advanced PPS is constructed, which could be used for the preparation for the possible terror attacks in the NPPs

[Broader indication for treatment with statins; the 'heart protection study'

NARCIS (Netherlands)

Stalenhoef, A.F.H.; Stuyt, P.M.J.

2002-01-01

The introduction of statins has been a breakthrough in the treatment of hypercholesterolaemia. Statins are safe and effective in reducing the risk of coronary heart disease in the general population. The 'Heart protection study' has provided evidence for the benefit of statin treatment in much

Study on the application of sensitizing and protective agent in the process of radiation chemistry

International Nuclear Information System (INIS)

Kamal, Z.

1976-01-01

The role of sensitizing agent and protective agent in the process of radiation chemistry is studied. Direct and indirect radiation effects on bio molecules, molecular and sensitizing agent mechanism, electron activities as the basis for sensitizing agent mechanism, protective agent mechanism on irradiated macro molecules, and kinds of protective and sensitizing agents, are discussed. (RUW)

Resilience and social support as protective factors against abuse of patients with dementia: A study on family caregivers.

Science.gov (United States)

Serra, Lídia; Contador, Israel; Fernández-Calvo, Bernardino; Ruisoto, Pablo; Jenaro, Cristina; Flores, Noelia; Ramos, Francisco; Rivera-Navarro, Jesús

2018-05-24

Scientific literature has identified different vulnerability factors associated to abuse in people with dementia (PWD), but little is known about the psychosocial protective variables against abuse. The main objective of this study is to investigate a set of caregiver and patient factors linked to abuse-related behavior of PWD. A total of 326 primary and family caregivers, residents of the Castilla and León community (Spain), were evaluated. All participants filled out a standardized protocol, which assessed the sociodemographic characteristics, patient and care-related variables, as well as the perceived burden, resilience, and social support. Abuse-related behavior was evaluated using the Caregiver Abuse Screen. Results show that the severity of cognitive impairment and behavior disorders of PWD, a greater number of caregiving hours, a worse previous relationship with the caregiver, and perceived burden are positively related with abuse. However, resilience and social support showed a negative relationship with Caregiver Abuse Screen scores, suggesting a protective effect on abuse, even after controlling the effect of a number of covariates. Indeed, resilience was the only variable that remained significant after including the effect of burden. This paper states the role of burden in abuse of PWD, while resilience and social support are abuse protective factors. These variables should be considered in future guidelines for the prevention of abuse against PWD. Copyright © 2018 John Wiley & Sons, Ltd.

Student Leadership Role for Environmental Protection

Directory of Open Access Journals (Sweden)

Ramona Isabel S. Ramirez

2017-05-01

Full Text Available The research focuses on the role of student organizations in the promotion of environmental education and protection. It assessed the student organizations’ initiatives and activities that address the environmental issues and problems. It determined whether student leadership can be an effective tool in addressing environmental concerns and promote environmental education. Descriptiveevaluative methods of research were used in the study. Documentary analysis was used to determine the programs, projects and activities conducted by the different student organizations along environmental education and protection. Interview and focused group discussions were employed to validate the secondary data and identify problems and constraints encountered by the organization. Results of the study showed that the University supports student leadership through the student organizations. Student organizations are empowered and given rights and privileges’ as stipulated in the student handbook. There were more than forty accredited student organizations in CBSUA. All of them initiated programs/projects and activities that are environment related as required by the university. Student leadership through student organizations is an effective tool in promoting environmental education and protection. Student empowerment through student organizations can promote student involvement in the most pressing concerns of environment protection.

Safety study of fire protection for nuclear fuel cycle facility

International Nuclear Information System (INIS)

2013-01-01

Insufficiencies in the fire protection system of the nuclear reactor facilities were pointed out when the fire occurred due to the Niigata prefecture-Chuetsu-oki Earthquake in July, 2007. This prompted the revision of the fire protection safety examination guideline for nuclear reactors as well as commercial guidelines. The commercial guidelines have been endorsed by the regulatory body. Now commercial fire protection standards for nuclear facilities such as the design guideline and the management guideline for protecting fire in the Light Water Reactors (LWRs) are available, however, those to apply to the nuclear fuel cycle facilities such as mixed oxide fuel fabrication facility (MFFF) have not been established. For the improvement of fire protection system of the nuclear fuel cycle facilities, the development of a standard for the fire protection, corresponding to the commercial standard for LWRs were required. Thus, Japan Nuclear Energy Safety Organization (JNES) formulated a fire protection guidelines for nuclear fuel cycle facilities as a standard relevant to the fire protection of the nuclear fuel cycle facilities considering functions specific to the nuclear fuel cycle facilities. In formulating the guidelines, investigation has been conduced on the commercial guidelines for nuclear reactors in Japan and the standards relevant to the fire protection of nuclear facilities in USA and other countries as well as non-nuclear industrial fire protection standards. The guideline consists of two parts; Equipments and Management, as the commercial guidances of the nuclear reactor. In addition, the acquisition of fire evaluation data for a components (an electric cabinet, cable, oil etc.) targeted for spread of fire and the evaluation model of fire source were continued for the fire hazard analysis (FHA). (author)

Evaluation of radiation protection in interventional orthopedic procedures in Khartoum state

International Nuclear Information System (INIS)

Ibrahim, M. Y. A.

2013-06-01

In this study an evaluation of radiation safety and protection in interventional orthopedic procedures for the staff in three theatres in Khartoum state was conducted. To evaluate radiation protection program and staff knowledge with regard to radiation protection a questionnaire was designed and distributed among the staff there. Integrity check was conducted on the available radiation tools ( lead aprons) to ensure that they provide optimal protection when positioned appropriately. Also dose rate was measured around the theatre to evaluate the level of leakage radiation. Finally the absorbed dose to orthopedic specialists was measured during several procedures. The study showed the absence of most of the radiation protection and safety procedures that ensure the protection of of workers and lack of radiation protection program. The integrity check conducted on lead aprons showed uncapable crack in about 24% of the checked aprons. And in spite of this, there was no action taken to withdraw those faulty aprons or to replace them due to the acute shortage of the aprons available in the three centers and this will cause unjustified radiation exposure to the staff. The level of radiation around the theatres was found to fall within the acceptable limit according to the international commission of radiation protection (ICRP) recommendations that -if implemented -could improve the status of radiation protection in interventional orthopedic procedures. The improve. The important recommendations are to establish a single regulatory authority in Sudan independent from any user or promotion of radiation as well as to conduct periodically training courses for orthopedic staff on radiation protection in orthopedic interventional procedures.(Author)

Deformation and Heat Transfer on Three Sides Protected Beams under Fire Accident

Science.gov (United States)

Imran, M.; Liew, M. S.; Garcia, E. M.; Nasif, M. S.; Yassin, A. Y. M.; Niazi, U. M.

2018-04-01

Fire accidents are common in oil and gas industry. The application of passive fire protection (PFP) is a costly solution. The PFP is applied only on critical structural members to optimise project cost. In some cases, beams cannot be protected from the top flange in order to accommodate for the placement of pipe supports and grating. It is important to understand the thermal and mechanical response of beam under such condition. This paper discusses the response of steel beam under ISO 834 fire protected, unprotected and three sides protected beams. The model validated against an experimental study. The experimental study has shown good agreement with FE model. The study revealed that the beams protected from three sides heat-up faster compare to fully protected beam showing different temperature gradient. However, the affects load carrying capacity are insignificant under ISO 834 fire.

High-anxious individuals show increased chronic stress burden, decreased protective immunity, and increased cancer progression in a mouse model of squamous cell carcinoma.

Directory of Open Access Journals (Sweden)

Firdaus S Dhabhar

Full Text Available In spite of widespread anecdotal and scientific evidence much remains to be understood about the long-suspected connection between psychological factors and susceptibility to cancer. The skin is the most common site of cancer, accounting for nearly half of all cancers in the US, with approximately 2-3 million cases of non-melanoma cancers occurring each year worldwide. We hypothesized that a high-anxious, stress-prone behavioral phenotype would result in a higher chronic stress burden, lower protective-immunity, and increased progression of the immuno-responsive skin cancer, squamous cell carcinoma. SKH1 mice were phenotyped as high- or low-anxious at baseline, and subsequently exposed to ultraviolet-B light (1 minimal erythemal dose (MED, 3 times/week, 10-weeks. The significant strengths of this cancer model are that it uses a normal, immunocompetent, outbred strain, without surgery/injection of exogenous tumor cells/cell lines, and produces lesions that resemble human tumors. Tumors were counted weekly (primary outcome, and tissues collected during early and late phases of tumor development. Chemokine/cytokine gene-expression was quantified by PCR, tumor-infiltrating helper (Th, cytolytic (CTL, and regulatory (Treg T cells by immunohistochemistry, lymph node T and B cells by flow cytometry, adrenal and plasma corticosterone and tissue vascular-endothelial-growth-factor (VEGF by ELISA. High-anxious mice showed a higher tumor burden during all phases of tumor development. They also showed: higher corticosterone levels (indicating greater chronic stress burden, increased CCL22 expression and Treg infiltration (increased tumor-recruited immuno-suppression, lower CTACK/CCL27, IL-12, and IFN-γ gene-expression and lower numbers of tumor infiltrating Th and CTLs (suppressed protective immunity, and higher VEGF concentrations (increased tumor angiogenesis/invasion/metastasis. These results suggest that the deleterious effects of high trait anxiety

Study of protective coatings for aluminum die casting molds

Energy Technology Data Exchange (ETDEWEB)

Peter, Ildiko, E-mail: ildiko.peter@polito.it; Rosso, Mario; Gobber, Federico Simone

2015-12-15

Highlights: • Development and characterization of some protective coatings on steel substrate, realized by plasma spray techniques, were presented. • The substrate material used is a Cr–Mo–V based hot work tool steel. • The main attention is on the study of wear and on the characterization of the interface, because of their key role in determining the resistance of the coating layer. • Simulation of friction and wear processes is performed by pin-on-disk test and the tested samples are observed by scanning electron microscopy. - Abstract: In this paper, the development and characterization of some protective coatings on steel substrate are presented. The coatings are realized by plasma spray techniques. The substrate material used is a Cr–Mo–V based hot work tool steel, initially submitted to vacuum heat treatment to achieve homogeneous hardness. The main attention is focused on the study of wear and on the characterization of the interface between the substrate material and the coating layer, because of their key role in determining the resistance of the coating layer. Simulation of friction and wear processes is performed by pin-on-disk test and the tested samples are observed by scanning electron microscopy.

Skin cancer knowledge and sun protection behavior among nursing students.

Science.gov (United States)

Yilmaz, Medine; Yavuz, Betul; Subasi, Media; Kartal, Asiye; Celebioglu, Aysun; Kacar, Halime; Adana, Filiz; Ozyurek, Pakize; Altiparmak, Saliha

2015-01-01

The objective of this study was to determine skin cancer knowledge and sun protection behavior among nursing students. A total of 1178 nursing students in the Aegean Region of Turkey took part in this descriptive study. A score for knowledge on protection against skin cancer and a score for protective behavior against skin cancer were calculated. In this study, first year students sunbathed more in the middle of the day than fourth year students, and their knowledge of skin cancer was lower. No statistical difference was determined for protective behavior between the two groups. The knowledge levels and protective behavior of first year students were alarmingly low, but the average scores for knowledge and behavior of the fourth year university students were higher. The knowledge levels of the fourth year students were average but their protective behavior was insufficient. It was found that the knowledge levels and the levels of protective behavior of light-skinned students were higher. This study revealed that the knowledge levels and protective behavior of first year nursing students against the harmful effects of the sun and for protection against skin cancer were alarmingly low. It also showed that the knowledge levels of the fourth year nursing students were average, but that their protective behavior was very insufficient. These findings suggest that it is of extreme importance to acquire knowledge and behavior for protection against skin cancers in the education of nursing students. © 2014 The Authors. Japan Journal of Nursing Science © 2014 Japan Academy of Nursing Science.

Numerical case studies of vertical wall fire protection using water spray

Directory of Open Access Journals (Sweden)

L.M. Zhao

2014-11-01

Full Text Available Studies of vertical wall fire protection are evaluated with numerical method. Typical fire cases such as heated dry wall and upward flame spread have been validated. Results predicted by simulations are found to agree with experiment results. The combustion behavior and flame development of vertical polymethylmethacrylate slabs with different water flow rates are explored and discussed. Water spray is found to be capable of strengthening the fire resistance of combustible even under high heat flux radiation. Provided result and data are expected to provide reference for fire protection methods design and development of modern buildings.

Empirical study on the feasibility of measures for public self-protection capability enhancement

International Nuclear Information System (INIS)

Goersch, Henning G.; Werner, Ute

2011-01-01

The empirical study on the feasibility of measures for public self-protection capability enhancement covers the following issues with several sections: (1) Introduction: scope of the study; structure of the study. (2) Issue coherence: self-protection; reduction and prevention of damage by personal emergency preparedness, personal emergency preparedness in Germany. (3) Solution coherence: scientific approaches, development of practical problem solution approaches, proposal of a promotion system. (4) Empirical studies: Promotion system evaluation by experts; questioning of the public; Delphi-study on minimum standards in emergency preparedness; local networks in emergency preparedness. (5) Evaluation of models for personal emergency preparedness (M3P). (6) Integration of all research results into the approach of emergency preparedness: scope; recommendations, conclusions.

Risk exposures for human ornithosis in a poultry processing plant modified by use of personal protective equipment: an analytical outbreak study.

Science.gov (United States)

Williams, C J; Sillis, M; Fearne, V; Pezzoli, L; Beasley, G; Bracebridge, S; Reacher, M; Nair, P

2013-09-01

Ornithosis outbreaks in poultry processing plants are well-described, but evidence for preventive measures is currently lacking. This study describes a case-control study into an outbreak of ornithosis at a poultry processing plant in the East of England, identified following three employees being admitted to hospital. Workers at the affected plant were recruited via their employer, with exposures assessed using a self-completed questionnaire. Cases were ascertained using serological methods or direct antigen detection in sputum. 63/225 (28%) staff participated, with 10% of participants showing evidence of recent infection. Exposure to the killing/defeathering and automated evisceration areas, and contact with viscera or blood were the main risk factors for infection. Personal protective equipment (goggles and FFP3 masks) reduced the effect of exposure to risk areas and to self-contamination with potentially infectious material. Our study provides some evidence of effectiveness for respiratory protective equipment in poultry processing plants where there is a known and current risk of ornithosis. Further studies are required to confirm this tentative finding, but in the meantime respiratory protective equipment is recommended as a precautionary measure in plants where outbreaks of ornithosis occur.

Coral reefs for coastal protection: A new methodological approach and engineering case study in Grenada.

Science.gov (United States)

Reguero, Borja G; Beck, Michael W; Agostini, Vera N; Kramer, Philip; Hancock, Boze

2018-03-15

Coastal communities in tropical environments are at increasing risk from both environmental degradation and climate change and require urgent local adaptation action. Evidences show coral reefs play a critical role in wave attenuation but relatively little direct connection has been drawn between these effects and impacts on shorelines. Reefs are rarely assessed for their coastal protection service and thus not managed for their infrastructure benefits, while widespread damage and degradation continues. This paper presents a systematic approach to assess the protective role of coral reefs and to examine solutions based on the reef's influence on wave propagation patterns. Portions of the shoreline of Grenville Bay, Grenada, have seen acute shoreline erosion and coastal flooding. This paper (i) analyzes the historical changes in the shoreline and the local marine, (ii) assess the role of coral reefs in shoreline positioning through a shoreline equilibrium model first applied to coral reef environments, and (iii) design and begin implementation of a reef-based solution to reduce erosion and flooding. Coastline changes in the bay over the past 6 decades are analyzed from bathymetry and benthic surveys, historical imagery, historical wave and sea level data and modeling of wave dynamics. The analysis shows that, at present, the healthy and well-developed coral reefs system in the southern bay keeps the shoreline in equilibrium and stable, whereas reef degradation in the northern bay is linked with severe coastal erosion. A comparison of wave energy modeling for past bathymetry indicates that degradation of the coral reefs better explains erosion than changes in climate and historical sea level rise. Using this knowledge on how reefs affect the hydrodynamics, a reef restoration solution is designed and studied to ameliorate the coastal erosion and flooding. A characteristic design provides a modular design that can meet specific engineering, ecological and

Dietary Phytosterols Protective Against Peptic Ulceration

Science.gov (United States)

Tovey, Frank I; Capanoglu, Doga; Langley, G. John; Herniman, Julie M; Bor, Serhat; Ozutemiz, Omer; Hobsley, Michael; Bardhan, Karna Dev; Linclau, Bruno

2011-01-01

Background In developing countries the prevalence of duodenal ulceration is related to the staple diet and not to the prevalence of Helicobacter pylori. Experiments using animal peptic ulcer models show that the lipid fraction in foods from the staple diets of low prevalence areas gives protection against ulceration, including ulceration due to non-steroidal anti-inflammatory drugs (NSAIDs), and also promotes healing of ulceration. The lipid from the pulse Dolichos biflorus (Horse gram) was highly active and used for further investigations. Further experiments showed the phospholipids, sterol esters and sterols present in Horse gram lipid were gastroprotective. Dietary phospholipids are known to be protective, but the nature of protective sterols in staple diets is not known. The present research investigates the nature of the protective phytosterols. Methods Sterol fractions were extracted from the lipid in Dolichos biflorus and tested for gastroprotection using the rat ethanol model. The fractions showing protective activity were isolated and identification of the components was investigated by Gas Chromatography-Mass Spectrometry (GC-MS). Results The protective phytosterol fraction was shown to consist of stigmasterol, β-sitosterol and a third as yet unidentified sterol, isomeric with β-sitosterol. Conclusions Dietary changes, affecting the intake of protective phospholipids and phytosterols, may reduce the prevalence of duodenal ulceration in areas of high prevalence and may reduce the incidence of recurrent duodenal ulceration after healing and elimination of Helicobacter pylori infection. A combination of phospholipids and phytosterols, such as found in the lipid fraction of ulceroprotecive foods, may be of value in giving protection against the ulcerogenic effect of NSAIDs. PMID:27942332

Some methodologies for the optimization of radiation protection

International Nuclear Information System (INIS)

Oudiz, A.; Uzzan, G.

1979-01-01

Optimization of radiation protection in the nuclear power sector calls for decision-making studies with a view to elucidating the balance between expenditure on protection and health risks. The quantitative methods used for reaching such decisions are numerous and the cost-benefit analysis suggested by the ICRP is only one example. Others are cost-effectiveness analysis, multi-attribute analysis, utility functions and so on. The paper summarizes the principles of these different methods and describes the different aspects of a decision study as well as the manner in which they are interrelated. It emerges that optimization, or rather rationalization, of radiation protection options can be approached via many different quantitative methods, some of which differ appreciably from cost-benefit analysis. An exploratory investigation of these methods in particular decision-making contexts may in the future show some to be superior to others and better suited to general use in radiation protection. (author)

Self-protective strategies, violence and psychopathy: theory and a case study.

Science.gov (United States)

Nørbech, Peder Chr Bryhn; Crittenden, Patricia M; Hartmann, Ellen

2013-01-01

Although it has been proposed that attachment is a key factor in psychopathy and violence, conceptualization of its potential role remains limited. This article uses the dynamic-maturational model of attachment and adaptation (DMM; Crittenden, 2008 ) and a case study to illustrate an etiological model of psychopathy and violence. The Adult Attachment Interview (AAI; George, Kaplan, & Main, 1984 -1996), coded according to the DMM system (Crittenden & Landini, 2011 ), was used to identify the participant's self-protective attachment strategies, and to explore indexes indicating opportunities for change. To allow a more elaborated understanding of this participant's personality, AAI findings were compared and contrasted with the Rorschach method (Rorschach, 1921 /1942). The AAI indicated unresolved loss and trauma, alternation between delusionally idealizing dismissive (Type A) and menacing-paranoid entangled (Type C) strategies, possible depression, and the potential for reorganization. The Rorschach showed many similarities with the AAI findings. Implications for the understanding of psychopathy, violence, and treatment are presented.

Defining the Key Competencies in Radiation Protection for Endovascular Procedures: A Multispecialty Delphi Consensus Study.

Science.gov (United States)

Doyen, Bart; Maurel, Blandine; Cole, Jonathan; Maertens, Heidi; Mastracci, Tara; Van Herzeele, Isabelle

2018-02-01

Radiation protection training courses currently focus on broad knowledge topics which may not always be relevant in daily practice. The goal of this study was to determine the key competencies in radiation protection that every endovascular team member should possess and apply routinely, through multispecialty clinical content expert consensus. Consensus was obtained through a two round modified Delphi methodology. The expert panel consisted of European vascular surgeons, interventional radiologists, and interventional cardiologists/angiologists experienced in endovascular procedures. An initial list of statements, covering knowledge skills, technical skills and attitudes was created, based on a literature search. Additional statements could be suggested by the experts in the first Delphi round. Each of the statements had to be rated on a 5- point Likert scale. A statement was considered to be a key competency when the internal consistency was greater than alpha = 0.80 and at least 80% of the experts agreed (rating 4/5) or strongly agreed (rating 5/5) with the statement. Questionnaires were emailed to panel members using the Surveymonkey service. Forty-one of 65 (63.1%) invited experts agreed to participate in the study. The response rates were 36 out of 41 (87.8%): overall 38 out of 41(92.6%) in the first round and 36 out of 38 (94.7%) in the second round. The 71 primary statements were supplemented with nine items suggested by the panel. The results showed excellent consensus among responders (Cronbach's alpha = 0.937 first round; 0.958 s round). Experts achieved a consensus that 30 of 33 knowledge skills (90.9%), 23 of 27 technical skills (82.1%), and 15 of 20 attitudes (75.0%) should be considered as key competencies. A multispecialty European endovascular expert panel reached consensus about the key competencies in radiation protection. These results may serve to create practical and relevant radiation protection training courses in the future, enhancing

The study of patient exposure and protection from dental radiography

International Nuclear Information System (INIS)

Park, Tae Won

1979-01-01

The utilization of x-ray for diagnosis and examination is increasing by about 5-15% every year, therefore, it would be mandatory to protect the patients from exposures and so, studies in this field are performed even now. In dental field, the area of irradiation is limited any to the head and neck area, but the irradiated angle is varied following the objected tooth, so the adjacent structures lens and thyroid gland would be fragile to radiation. And the scattered radiation is one of the complicated problems in the protection because of specificity of dental x-ray and its object structures. The author, by using TLD(Thermoluminescent Dosimeter; Teledyne Isotopes Model 7300, Element; TLD 200(CaF2: Dy) and Capintec(Capintec Model 192, PM-30 Diagnostic chamber 28 ml active volume), tried a measurement of air dose distribution of the scattered radiation and the irradiated dose of lens and thyroid gland under the condition of taking the film on the left maxillary molar. The results were as follows: 1. The half value layer of adapted dental x-ray machine was measured, and is 1.44 mm Al. 2. The time of irradiation on the left maxillary molar in the Alderson Rando Phantom, the measured doses of left and right lens, and thyroid gland were 8, 9 mR, 1, 2 mR and 2, 8 mR. Under the same conditions, the scattered radiation at the distance of 1 meter from the phantom were 84 μR at the front side, 11 μR at the back side, 18 μR at the right side and 72 μR at the left side. 3. Under the same conditions, the dose showed higher value by about 5% in the presence of object(phantom) than in the case of absence.

Strengthening the scientific basis of radiological protection

International Nuclear Information System (INIS)

Lazo, Edward

2016-01-01

, 1998 and 2007). With these analyses, the CRPPH has assessed the possible implications that emerging scientific results (e.g. recent findings on radiation effects on the lens of the eye), or that possible results (e.g. ongoing epidemiological studies that could show statistically significant cancer risks, or that could show no cancer risks at doses below 50 mSv) could have for the way that radiological protection is regulated and applied. The latest report in this series, Radiological Protection Science and Application (NEA, 2016), performs such an assessment for today's level of scientific understanding. (author)

Radiation Protection Studies of International Space Station Extravehicular Activity Space Suits

Science.gov (United States)

Cucinotta, Francis A. (Editor); Shavers, Mark R. (Editor); Saganti, Premkumar B. (Editor); Miller, Jack (Editor)

2003-01-01

This publication describes recent investigations that evaluate radiation shielding characteristics of NASA's and the Russian Space Agency's space suits. The introduction describes the suits and presents goals of several experiments performed with them. The first chapter provides background information about the dynamic radiation environment experienced at ISS and summarized radiation health and protection requirements for activities in low Earth orbit. Supporting studies report the development and application of a computer model of the EMU space suit and the difficulty of shielding EVA crewmembers from high-energy reentrant electrons, a previously unevaluated component of the space radiation environment. Chapters 2 through 6 describe experiments that evaluate the space suits' radiation shielding characteristics. Chapter 7 describes a study of the potential radiological health impact on EVA crewmembers of two virtually unexamined environmental sources of high-energy electrons-reentrant trapped electrons and atmospheric albedo or "splash" electrons. The radiological consequences of those sources have not been evaluated previously and, under closer scrutiny. A detailed computational model of the shielding distribution provided by components of the NASA astronauts' EMU is being developed for exposure evaluation studies. The model is introduced in Chapters 8 and 9 and used in Chapter 10 to investigate how trapped particle anisotropy impacts female organ doses during EVA. Chapter 11 presents a review of issues related to estimating skin cancer risk form space radiation. The final chapter contains conclusions about the protective qualities of the suit brought to light form these studies, as well as recommendations for future operational radiation protection.

Radiological protection survey results about radiodiagnosis protection practices in Cuba

International Nuclear Information System (INIS)

Jova S, L.; Morales M, J.A.; Quevedo, J.R.; Medina, J.R.; Naranjo, A.M.; Fornet, O.M.

1996-01-01

In order to identify radiation protection current situation in national X-ray diagnostic practice , the State (cuban) Supervision System for Radiation and Nuclear Safety carried out in 1992 a survey which was planned for projection of future regulatory activities in this field. Survey covers the most important aspects related to radiation protection of occupationally exposed workers, patients and general population. Surveyed sample included a total of 52 X-ray units, sited in 7 dental clinics, 2 polyclinics and 13 hospitals, from 7 provinces of the country. Results showed that the organization of radiation protection in terms of personnel specially designated to carry out surveillance and control activities and level of documentation is deficient. Survey evidenced the general lack of safety and quality culture among technologists and radiologists which is mainly reflected in non regular application of basic patient protection measures (shielding, collimation, use of proper filtration among others) and non regular execution of basic quality inspection of employed radiographic systems. (authors). 4 refs., 1 fig

Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals.

Science.gov (United States)

Vemuri, Prashanthi; Knopman, David S; Lesnick, Timothy G; Przybelski, Scott A; Mielke, Michelle M; Graff-Radford, Jonathan; Murray, Melissa E; Roberts, Rosebud O; Vassilaki, Maria; Lowe, Val J; Machulda, Mary M; Jones, David T; Petersen, Ronald C; Jack, Clifford R

2017-06-01

While amyloid and neurodegeneration are viewed together as Alzheimer disease pathophysiology (ADP), the factors that influence amyloid and AD-pattern neurodegeneration may be considerably different. Protection from these ADP factors may be important for aging without significant ADP. To identify the combined and independent protective factors for amyloid and AD-pattern neurodegeneration in a population-based sample and to test the hypothesis that "exceptional agers" with advanced ages do not have significant ADP because they have protective factors for amyloid and neurodegeneration. This cohort study conducted a prospective analysis of 942 elderly individuals (70-≥90 years) with magnetic resonance imaging and Pittsburgh compound B-positron emission tomography scans enrolled in the Mayo Clinic Study of Aging, a longitudinal population-based study of cognitive aging in Olmsted County, Minnesota. We operationalized "exceptional aging" without ADP by considering individuals 85 years or older to be without significant evidence of ADP. We evaluated predictors including demographics, APOE, intellectual enrichment, midlife risk factors (physical inactivity, obesity, smoking, diabetes, hypertension, and dyslipidemia), and the total number of late-life cardiac and metabolic conditions. We used multivariate linear regression models to identify the combined and independent protective factors for amyloid and AD-pattern neurodegeneration. Using a subsample of the cohort 85 years of age or older, we computed Cohen d-based effect size estimations to compare the quantitative strength of each predictor variable in their contribution with exceptional aging without ADP. The study participants included 423 (45%) women and the average age of participants was 79.7 (5.9) years. Apart from demographics and the APOE genotype, only midlife dyslipidemia was associated with amyloid deposition. Obesity, smoking, diabetes, hypertension, and cardiac and metabolic conditions, but not

Local food protection and safety infrastructure and capacity: a Maryland case study.

Science.gov (United States)

Kufel, Joanna Zablotsky; Resnick, Beth A; Fox, Mary; Frattaroli, Shannon; Gielen, Andrea; Burke, Thomas A

2011-01-01

In Maryland, county Food Protection Programs (FPP), housed within Environmental Public Health (EPH) Divisions, maintain responsibility for regular inspection of all food service facilities (FSF). With growing concerns about how our food supply is protected, it is important to determine the state and effectiveness of our food safety systems. This research elucidates the roles, responsibilities, strengths, and weaknesses of Food Safety and Protection Programs in Maryland. A 16-question survey tool, which addressed facets of the local food protection infrastructure, including FSF inspections, staffing, budget, and foodborne illness surveillance, was distributed to all 24 county FPP. The number of FSF in Maryland increased 97% from 2001 to 2006 and counties had an average inspection completion rate of 73%, with a 4% increase over the time period. Statewide, there were 4.1 EPH full-time employees (FTE) per 10 000 population and 1.6 FPP FTE per 10 000 population. EPH Division budgets increased 63% statewide, from $19.5 million in 2000 to $31.9 million in 2007. FPP budgets also increased 59% over the period, from $6.2 million in 2000 to $9.8 million in 2007. This study offers new quantitative measures of the demands, capacities, and performance of Food Protection and Safety Programs in Maryland. This assessment of local EPH and FPP capacity also offers insight into the strengths and weaknesses of the local food protection and safety infrastructure. Importantly, it reveals an infrastructure and dedicated food protection workforce that inspects the food supply and responds to foodborne illness outbreaks. Yet, resources vary substantially from county to county, impacting which services can be provided and how well they can be performed. This can, in turn, impact the potential risk of foodborne illness and the public's overall health.

Natural analog study of engineered protective barriers at the Hanford Site

International Nuclear Information System (INIS)

Bjornstad, B.N.; Teel, S.S.

1993-09-01

The purpose of this study is to evaluate surficial sedimentary deposits formed in the Pasco Basin over the geologic past as analogs for engineered protective barriers. Evidence for likely changes to be expected in an engineered barrier are preserved in geologically recent deposits. Although the design life of the engineered bonier is only 1,000 years, soils and sediments of this age are uncommon in the Pasco Basin. The evidence of and probability for the following natural processes that could adversely affect the long-term stability of an engineered protective barrier reviewed in this report are deflation by wind, soil compaction, soil eluviation/illuviation, bioturbation, and cryoturbation

Moderate alcohol consumption may protect against overt autoimmune hypothyroidism: a population-based casecontrol study

DEFF Research Database (Denmark)

Carl, Allan; Pedersen, Inge Blow; Knudsen, Nils

2012-01-01

OBJECTIVE: Alcohol consumption is an important protective risk factor for many autoimmune diseases. We wished to study the association between alcohol consumption and autoimmune hypothyroidism. DESIGN: Population-based, case-control study, 1997-2001, Denmark. METHODS: Patients with newly diagnose......, or region of inhabitancy. CONCLUSIONS: Alcohol consumption seems to confer considerable protection against development of overt autoimmune hypothyroidism irrespective of sex and type of alcohol consumed.......OBJECTIVE: Alcohol consumption is an important protective risk factor for many autoimmune diseases. We wished to study the association between alcohol consumption and autoimmune hypothyroidism. DESIGN: Population-based, case-control study, 1997-2001, Denmark. METHODS: Patients with newly diagnosed...... of alcohol per week were as follows: 0 units/week, 1.98 (1.21-3.33); 11-20 units/week, 0.41 (0.20-0.83); and ≥21 units/week, 0.90 (0.41-2.00). Similar results were found for maximum previous alcohol consumption during a calendar year. No interaction was found with type of alcohol consumed (wine vs beer), sex...

Data Protection for Virtual Data Centers

CERN Document Server

Buffington, Jason

2010-01-01

Essential information on how to protect data in virtual environments!. Virtualization is changing the data center architecture and as a result, data protection is is quickly evolving as well. This unique book, written by an industry expert with over eighteen years of data storage/backup experience, shows you how to approach, protect, and manage data in a virtualized environment. You'll get up to speed on data protection problems, explore the data protection technologies available today, see how to adapt to virtualization, and more. The book uses a "good, better, best" approach, explo

Evaportranspiration studies for protective barriers: FY 1989 status report

International Nuclear Information System (INIS)

Link, S.O.; Thiede, M.E.; Downs, J.L.; Lettau, D.J.; Waugh, W.J.

1992-05-01

This document describes the results of technological developments and experiments at the Small Tube Lysimeter Facility. The objective of this research is to develop the capability to predict evapotranspiration in support of studies of water infiltration control for the Hanford Protective Barrier Development Program. Evapotranspiration is the combined loss of water from plants and soil surfaces to the atmosphere. This process must be predictable to adequately model soil water dynamics. We develop a miniature greenhouse (gas exchange chamber), where internal temperature and relative humidity can be controlled. With this device we measured evapotranspiration, transpiration, and carbon dioxide exchange rates from lysimeters with various surface and plant characteristics. We tested the effect on gas exchange rates and sand, gravel, admix, and soil surfaces in lysimeters where, cheat-grass, Bromus tectorum, had been seeded. Results showed that evapotranspiration was unaffected by the surface treatments. Estimated transpiration rates were higher for plants growing in sand compared with rates for plants growing in the admix and soil treatments. Soil evaporation rates were higher in the gravel treatment than in the sand treatment. Future research will entail parameterization of relationships between evapotranspiration, transpiration, soil evaporation, carbon dioxide exchange, and the abiotic and biotic factors that drive these processes for model development

Stress in Community Health Agents: a Bioethics Protection Perspective

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Ulysses Rodrigues de Castro

2014-09-01

Full Text Available Health care professionals suffer from both regular job stress and caregiver stress that arises from the neglect of their work situation. As principles of bioethics protection, vertical protection ratio, health policies should also target health professionals. So, this paper seeks to understand the issue of stress in relation to mental health professionals, specifically the community health agents of the Federal District in Brazil. Methods: This study is an exploratory study that adopts a quantitative approach. Data were obtained by a questionnaire, that mesure social, work and stress factors, in 97 community health agents, a different class of health professional. The SPSS 19.0 program was used to mesure the results. Results: The sociodemographic data of respondentes revealed that the majority were women, 40,2% of the group members fall in the age range 30‒39 years, 51% of respondents were married and 57.7% were of middle socioeconomic status. All Pearson correlations were significant at the 0.01 level (two-tailed. The results show that all stressors are negatively correlated with the mental health factors. These results showed that mental health deteriorates with increased stress. The mental health indicators are strongly and positively associated, indicating that individuals with better mental health show greater personal, social and workplace support. Conclusions: The results indicate the need for management changes in the public health sector related to Bioethics Protection, which states that populations vulnerable to work exploitation should be protected by guaranteeing minimum working conditions.

Does bilirubin protect against developing diabetes mellitus?

Science.gov (United States)

Breimer, Lars H; Mikhailidis, Dimitri P

2016-01-01

After 25 years of evaluating bilirubin as a possible protective agent in neonatal and cardiovascular disease, interest has moved on to a exploring a possible protective role in diabetes mellitus (DM). This review finds conflicting prospective data for a protective relationship though there are retrospective, case-controlled data, that can only show association, which is not causality. Only prospective studies can show causality. Also, it would appear that the underlying biochemical assumptions do not readily translate from the animal to the human setting. Given that many factors impact on circulating bilirubin levels, it is not surprising that a clear-cut answer is not available; the jury is still out. Any relationship between DM and bilirubin might relate to intermediates in bilirubin metabolism, including relationships involving the genes for the enzymes participating in those steps. Nevertheless, the pursuit of bilirubin in disease causation is opening new avenues for research and if it is established that serum bilirubin can predict risks, much will have been achieved. The answer may have to come from molecular genetic analyses. Copyright © 2016 Elsevier Inc. All rights reserved.

Development and stability studies of sunscreen cream formulations containing three photo-protective filters

OpenAIRE

Smaoui, Slim; Ben Hlima, Hajer; Ben Chobba, Ines; Kadri, Adel

2013-01-01

The present study aimed to formulate and subsequently evaluate sunscreen cream (W/O/W emulsion) containing three photo-protective filters: benzophenone-3, ethylhexyl methoxycinnamate and titanium dioxide at different percentages. Formulations were stored at 8, 25 and 40 °C for four weeks to investigate their stability. Color, centrifugation, liquefaction, phase separation, pH and Sun Protection Factor (SPF) of sunscreen cream formulations were determined. The microbiological stability of the ...

Hybrid AC EL structures with thin protective ZnO film

International Nuclear Information System (INIS)

Tsvetkova, E; Dikov, H; Kolentsov, K; Yourukova, L; Zhechev, D; Steflekova, V

2008-01-01

Alternating current hybrid electroluminescent Al/SnO 2 /ZnS: Cu/ZnO/Al structures with blue emission have been prepared. In these ZnO films are used as protective layers. The optical properties of different RF magnetron sputtered ZnO films have been studied. The voltage - brightness characteristics of AC EL structures with a ZnO protective film and conventional structures with a TiO 2 protective layer are compared. The investigation shows that the brightness of the structures with a ZnO protective film is higher. The improved characteristics of these new hybrid structures could be used in preparing various systems for representation of permanent or variable light information

Studying the sensor response in the punch-through-protection region

CERN Document Server

Poley, Anne-luise; The ATLAS collaboration

2017-01-01

For the Phase-II Upgrade of the ATLAS detector, a new, all-silicon tracker will be constructed in order to cope with the increased track density and radiation level of the High Luminosity Large Hadron Collider. While silicon strip sensors are designed to minimise the fraction of dead material and maximise the active area of a sensor, concessions must be made to the requirements of operating a sensor in a particle physics detector. Sensor geometry features like the punch-through protection deviate from the standard sensor architecture and thereby affect the charge collection in that area. In order to study the signal collection of silicon strip sensors over their punch-through-protection area, ATLAS silicon strip sensors were scanned with a micro-focused X-ray beam at the Diamond Light Source. Due to the highly focused X-ray beam (2 × 3 µm) and the short average path length of an electron after interaction with an X-ray photon (≤ 2 μm), local signal collection in different sensor areas can be studied with...

Dynamics in the global protected-area estate since 2004.

Science.gov (United States)

Lewis, Edward; MacSharry, Brian; Juffe-Bignoli, Diego; Harris, Nyeema; Burrows, Georgina; Kingston, Naomi; Burgess, Neil D

2017-11-23

Nations of the world have committed to a number of goals and targets to address the global environmental challenges humanity faces. Protected areas have for centuries been a key strategy in conservation and play a major role in addressing current challenges. The most important tool used to track progress on protected area commitments is the World Database on Protected Areas (WDPA). Periodic assessments of the world's protected area estate show steady growth over the last two decades. However, the current method, which uses the latest version of the WDPA, does not show the true dynamic nature of protected areas over time, nor does it provide information on sites removed from the WDPA. In reality, this methodology can only show growth or remain stable. This paper presents a novel approach to assess protected area change over time using twelve temporally distinct versions of the WDPA that quantify area added, and removed, from the WDPA annually from 2004 to 2016. Results show that both the narrative of continual protected area growth and the counter-narrative of protected area removal are overly simplistic. The former because growth has been almost entirely marine and the latter because we demonstrate that some areas removed are re-protected in later years. Analysis indicates that, on average, 2.5 million km 2 is added to the WDPA annually and 1.1 million km 2 is removed. Reasons for the inclusion and removal of protected areas in the WDPA database are explored and discussed. To meet the 17% land coverage component of Aichi Biodiversity Target 11 by 2020, which stands at 14.7% in 2016, the world will either need to reduce the rate of protected area removal or increase the rate of protected area designation and addition to the WDPA. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Induction of protective immunity against toxoplasmosis in mice by ...

African Journals Online (AJOL)

The results showed that mice immunized by pcROP1 with or without alum produced high Th1 immune response compared with control groups. This type of DNA vaccine prolonged slightly the survival time. The current study showed that ROP1 DNA vaccine can induced partial protective response against toxoplasmosis.

Risk and protective factors for chronic diseases in adults: a population-based study

Directory of Open Access Journals (Sweden)

Danielle Cristina Guimarães da Silva

Full Text Available Abstract The article describes the relative frequency ok of risk and protective behaviors for chronic non-communicable diseases (NCDs in adults residing in Viçosa, Brazil. A cross-section-al population-based study including 1,226 adults living in the municipality. We used a structured questionnaire containing questions sociodemographic and behavioral The risk and protection factors evaluated were: smoking, physical activity, excessive consumption of alcohol and food consumption. The proportion of risk and protection factors was calculated in the total population, according to gender, education and socioeconomic status. The studied population has a high frequency of risk factors for NCDs, such as excessive consumption of alcoholic beverages, habit of consuming whole milk, habit of eating meat with visible fat, regular consumption of soft drinks and 78.5% did not achieve the minimum recommendation for physical activity in leisure time. With regard to protective factors, 86.2% of the population reported regular consumption of fruits and vegetables, and 73%, of beans. It was found the highest frequency of risk factors in among males, in younger people and middle socioeconomic status. This population has an urgent need for public policy of municipal planning to change this current scenario.

A Model for Protective Behavior against the Harmful Effects of Radiation based on Medical Institution Classifications

International Nuclear Information System (INIS)

Han, Eun Ok; Kwon, Deok Mun; Dong, Kyung Rae; Han, Seung Moo

2010-01-01

This study surveyed a total of 1,322 radiation technologist in health care institutions throughout Korea. This is a comparative study conducted on the levels of protective behavior against the harmful effects of radiation in heath care institutions which indicated that university hospitals and general hospitals showed higher level of protective behavior than for medical practitioners. This study found university hospitals have the following 7 characteristics to manage protective behavior against the harmful effects of radiation, protective environment, self-efficacy by distinction of task , self-efficacy, expectation of the protective behavior, the number of patients, level of the education related to the protection of the harmful effects of radiation and protective attitude. While general hospitals have the following 3 characteristics protective environment, expectation of the protective behavior and protective attitude. Hospitals have the following 4 characteristics protective environment, expectation of the protective behavior, protective attitude and self-efficacy and medical clinics have characteristics protective environment

A Model for Protective Behavior against the Harmful Effects of Radiation based on Medical Institution Classifications

Energy Technology Data Exchange (ETDEWEB)

Han, Eun Ok; Kwon, Deok Mun [Daegu Health College, Daegu (Korea, Republic of); Dong, Kyung Rae [Gwangju Health College University, Gwangju (Korea, Republic of); Han, Seung Moo [Kyung Hee University, Seoul (Korea, Republic of)

2010-12-15

This study surveyed a total of 1,322 radiation technologist in health care institutions throughout Korea. This is a comparative study conducted on the levels of protective behavior against the harmful effects of radiation in heath care institutions which indicated that university hospitals and general hospitals showed higher level of protective behavior than for medical practitioners. This study found university hospitals have the following 7 characteristics to manage protective behavior against the harmful effects of radiation, protective environment, self-efficacy by distinction of task , self-efficacy, expectation of the protective behavior, the number of patients, level of the education related to the protection of the harmful effects of radiation and protective attitude. While general hospitals have the following 3 characteristics protective environment, expectation of the protective behavior and protective attitude. Hospitals have the following 4 characteristics protective environment, expectation of the protective behavior, protective attitude and self-efficacy and medical clinics have characteristics protective environment.

Epidermal protection with cryogen spray cooling during high fluence pulsed dye laser irradiation: an ex vivo study.

Science.gov (United States)

Tunnell, J W; Nelson, J S; Torres, J H; Anvari, B

2000-01-01

Higher laser fluences than currently used in therapy (5-10 J/cm(2)) are expected to result in more effective treatment of port wine stain (PWS) birthmarks. However, higher incident fluences increase the risk of epidermal damage caused by absorption of light by melanin. Cryogen spray cooling offers an effective method to reduce epidermal injury during laser irradiation. The objective of this study was to determine whether high laser incident fluences (15-30 J/cm(2)) could be used while still protecting the epidermis in ex vivo human skin samples. Non-PWS skin from a human cadaver was irradiated with a Candela ScleroPlus Laser (lambda = 585 nm; pulse duration = 1.5 msec) by using various incident fluences (8-30 J/cm(2)) without and with cryogen spray cooling (refrigerant R-134a; spurt durations: 40-250 msec). Assessment of epidermal damage was based on histologic analysis. Relatively short spurt durations (40-100 msec) protected the epidermis for laser incident fluences comparable to current therapeutic levels (8-10 J/cm(2)). However, longer spurt durations (100-250 msec) increased the fluence threshold for epidermal damage by a factor of three (up to 30 J/cm(2)) in these ex vivo samples. Results of this ex vivo study show that epidermal protection from high laser incident fluences can be achieved by increasing the cryogen spurt duration immediately before pulsed laser exposure. Copyright 2000 Wiley-Liss, Inc.

Meta-analysis of dry cow management for dairy cattle. Part 1. Protection against new intramammary infections.

Science.gov (United States)

Halasa, T; Osterås, O; Hogeveen, H; van Werven, T; Nielen, M

2009-07-01

The objective of this study was to estimate the preventive effect of various dry cow management measures against quarter new intramammary infections (IMI) during the dry period up to 21 d postcalving. Moreover, the potential publication bias was assessed in the studies selected for this analysis. The intervention measures were blanket dry cow therapy (BDCT), selective dry cow therapy (SDCT), cloxacillin compared with other dry cow therapy products, and teat sealant. A meta-analysis relative risk (RR) was calculated per intervention and pathogen group when enough studies were available from the 33 selected studies. Results of the meta-analyses were examined using publication bias tests. Blanket dry cow therapy showed significant protection against new IMI caused by Streptococcus spp. [the pooled RR was 0.39 (0.30 to 0.51)] but no protection was observed against coliform new IMI [the pooled RR was 0.95 (0.81 to 1.10)]. After correction for publication bias, it became doubtful whether DCT is protective against new Staphylococcus spp. IMI. Cloxacillin showed similar protection against new quarter IMI compared with other DCT products [the pooled RR was 1.09 (0.94 to 1.25)]. Selective dry cow therapy showed higher protection against new IMI compared with no DCT [the pooled RR was 0.51 (0.30 to 0.86)]. However, BDCT showed more protection when compared with SDCT [the pooled RR was 0.55 (0.37 to 0.80)], but the inference about whether BDCT is superior to SDCT was dependent on whether the selection criteria for SDCT was at the cow or quarter level. Internal teat sealants showed significant protection against new IMI during the dry period [the pooled RR was 0.39 (0.18 to 0.82)]. Publication bias should be taken into account when attempts are made to review literature in a meta-analysis.

Radiation protection awareness in dentistry students

International Nuclear Information System (INIS)

Mehdizadeh, S.; Vaziefehdoust, S.

2007-01-01

Complete text of publication follows. Dentistry students were assessed in one of the school of dentistry in Iran. 11% of responders had attended a radiation protection course. This study showed that those who have attended this course had improved knowledge of ALARA principle, assessment of the impact of digital imaging in patient dose reduction and usage of personal dosimeter systems. Course attendance made no considerable difference to knowledge of the patient dose, dose reduction techniques and annual permissible dose limits of general public and radiation workers. The results of this study revealed that the majority of students have not received adequate radiation protection teaching and even if a course has been attended, overall knowledge is still poor and formal teaching at undergraduate level should be corrected in the future.

Occupational Noise Pollution and Hearing protection in selected industries

Directory of Open Access Journals (Sweden)

Ghorbanali Mohammadi

2014-01-01

Full Text Available ABSTRACT The use of technology in industries is ever increasing. With the introduction of this technology come new safety and human performance concerns. Hearing loss caused by industrial noise has been recognized for many years, and protection of employee hearing has been made mandatory by governmental agencies. This paper presents an investigation of occupational noise exposure and Personal hearing protective devices (PHPD in selected industries in the south-eastern Iran. A questionnaire has been used to collect data for workers with high noise exposure and Personal hearing protective devices (PHPD. The subjects were 354 industrial workers expose to noise pressure levels greater than the action level defined in Iranian legislation (85dB (A 8h/d. The results of this study indicated that only younger workers with minor professional experience and with high educational background are used PHPD to protect and preserve their hearing. The finding of this study shows that approximately 75% of the workers with age 18-36 reported the use of personal protective Devices at all the time, and 73% of workers with age more than 46 years old reported that they had never used them PHPD, even though it was mandatory in their workplaces. Statistical data show that, the percentage of male workers (82 with age more than 37 years old having headaches at workplace are higher than female (3.4 with the same age groups. A noise training and education program must be developed for industrial employees in order to protect them from hazardous noise pollution. Employers must play an important role in promoting the regular use of Personal hearing protective devices. Noise level in work areas must be considered in the early design of Hearing Conservation Program.

Individual protection equipments in nuclear environment: irradiation time influence

International Nuclear Information System (INIS)

Schieber, C.

1994-09-01

This study allowed to show that influence evaluation of diverse protection suits on the intervention times was undissociable of ergonomical characteristics of the tasks to be done. 15 tabs., 3 figs., 9 appendixes

Hibiscus vitifolius (Linn.) root extracts shows potent protective action against anti-tubercular drug induced hepatotoxicity.

Science.gov (United States)

Samuel, Anbu Jeba Sunilson John; Mohan, Syam; Chellappan, Dinesh Kumar; Kalusalingam, Anandarajagopal; Ariamuthu, Saraswathi

2012-05-07

The roots of Hibiscus vitifolius Linn. (Malvaceae) is used for the treatment of jaundice in the folklore system of medicine in India. This study is an attempt to evaluate the hepatoprotective activity of the roots of Hibiscus vitifolius against anti-tubercular drug induced hepatotoxicity. Hepatotoxicity was induced in albino rats of either sex by oral administration of a combination of three anti-tubercular drugs. Petroleum ether, chloroform, methanol and aqueous extracts of roots of Hibiscus vitifolius (400mg/kg/day) were evaluated for their possible hepatoprotective potential. All the extracts were found to be safe up to a dose of 2000mg/kg. Among the four extracts studied, oral administration of methanol extract of Hibiscus vitifolius at 400mg/kg showed significant difference in all the parameters when compared to control. There was a significant (PHibiscus vitifolius have potent hepatoprotective activity, thereby justifying its ethnopharmacological claim. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Risk-based flood protection planning under climate change and modeling uncertainty: a pre-alpine case study

Directory of Open Access Journals (Sweden)

B. Dittes

2018-05-01

Full Text Available Planning authorities are faced with a range of questions when planning flood protection measures: is the existing protection adequate for current and future demands or should it be extended? How will flood patterns change in the future? How should the uncertainty pertaining to this influence the planning decision, e.g., for delaying planning or including a safety margin? Is it sufficient to follow a protection criterion (e.g., to protect from the 100-year flood or should the planning be conducted in a risk-based way? How important is it for flood protection planning to accurately estimate flood frequency (changes, costs and damage? These are questions that we address for a medium-sized pre-alpine catchment in southern Germany, using a sequential Bayesian decision making framework that quantitatively addresses the full spectrum of uncertainty. We evaluate different flood protection systems considered by local agencies in a test study catchment. Despite large uncertainties in damage, cost and climate, the recommendation is robust for the most conservative approach. This demonstrates the feasibility of making robust decisions under large uncertainty. Furthermore, by comparison to a previous study, it highlights the benefits of risk-based planning over the planning of flood protection to a prescribed return period.

Risk-based flood protection planning under climate change and modeling uncertainty: a pre-alpine case study

Science.gov (United States)

Dittes, Beatrice; Kaiser, Maria; Špačková, Olga; Rieger, Wolfgang; Disse, Markus; Straub, Daniel

2018-05-01

Planning authorities are faced with a range of questions when planning flood protection measures: is the existing protection adequate for current and future demands or should it be extended? How will flood patterns change in the future? How should the uncertainty pertaining to this influence the planning decision, e.g., for delaying planning or including a safety margin? Is it sufficient to follow a protection criterion (e.g., to protect from the 100-year flood) or should the planning be conducted in a risk-based way? How important is it for flood protection planning to accurately estimate flood frequency (changes), costs and damage? These are questions that we address for a medium-sized pre-alpine catchment in southern Germany, using a sequential Bayesian decision making framework that quantitatively addresses the full spectrum of uncertainty. We evaluate different flood protection systems considered by local agencies in a test study catchment. Despite large uncertainties in damage, cost and climate, the recommendation is robust for the most conservative approach. This demonstrates the feasibility of making robust decisions under large uncertainty. Furthermore, by comparison to a previous study, it highlights the benefits of risk-based planning over the planning of flood protection to a prescribed return period.

Laboratory study of reinforcement protection with corrosion inhibitors

International Nuclear Information System (INIS)

Stefanescu, D.; Mihalache, M.; Mogosan, S.

2013-01-01

Concrete is a durable material and its performance as part of the containment function in NPPs has been good. However, experience shows that degradation of the reinforced concrete structures caused by the corrosion of the reinforcing steel represents more than 80% of all damages in the world. Much effort has been made to develop a corrosion inhibition process to prolong the life of existing structures and minimize corrosion damages in new structures. Migrating Corrosion Inhibitor technology was developed to protect the embedded steel rebar/concrete structure. These inhibitors can be incorporated as an admixture or can be surface impregnated on existing concrete structures. The effectiveness of two inhibitors (ethanolamine and diethanolamine) mixed in the reinforced concrete was evaluated by gravimetric measurements. The corrosion behavior of the steel rebar and the inhibiting effects of the amino alcohol chemistry in an aggressive environment were monitored using electrochemical measurements and scanning electron microscopy (SEM) investigations. (authors)

Protection against hyperthermic cell killing by alanine

International Nuclear Information System (INIS)

Cunningham, A.; Henle, K.J.; Moss, A.J.; Nagle, W.A.

1987-01-01

Compounds capable of protecting cells against hyperthermia may provide new insights into potential mechanisms of thermotolerance and cellular heat death. The authors characterized heat protection by alanine and related compounds as a function of concentration, temperature and preincubation time. Alanine was added either to complete medium or to HBSS before hyperthermia. Maximal heat protection required 3 hr, 37 0 ; longer preincubation intervals resulted in lower levels of protection. Addition of alanine to medium after hyperthermia had no protective effect. Protection was concentration dependent with a 20- or 200-fold increase in cell survival after 40 min, 45 0 C at 60 mM in medium or in HBSS, respectively. Higher alanine concentrations up to 120mM did not significantly increase heat protection. A 45 0 -heat survival curve showed that 100mM alanine increased the D/sub q/ by approx. 12 min with little change in the D/sub o/. Hyperthermia of 1 hr at temperatures between 42 0 and 45 0 indicated that 100mM alanine shifted the isotoxic temperature by 0.5 Celsius degrees. Polymers of either L or D,L alanine and related compounds, like pyruvate, also protected cells against heat killing. These results indicate that heat protection by alanine shows characteristics that are not shared by polyhydroxy compounds

Investigating public decisions about protecting wetlands.

Science.gov (United States)

Getzner, Michael

2002-03-01

Quantitative analyses of species protection decisions taken by public authorities regularly show that ecological factors, such as the probability of extinction, often play a minor role in the decision-making process. The taxonomy of the species or its potential conflict with economic development is a more powerful factor. This paper presents quantitative empirical research on the protection of wetlands in Austria. Econometrically estimated models show that geographical and ecological factors (such as the size of the area, elevation and importance for biodiversity) play a significant role in the protection of wetlands. Additional influences include conflict variables encoding the negative effects of the primary economic sector (agriculture) or tourism.

Studies on zeolite contribution to the sun protection properties of plant oil lotion rich in vitamin E

International Nuclear Information System (INIS)

Rendevski, S.; Mahmudi, N.

2012-01-01

Sunscreen lotions rich in vitamin E provide benefit in preventing and treating sunburns. The sun protection capacity of vitamin E's lotion formulations decrease with time of light exposure. The zeolite microparticles with previously absorbed vitamin E and added after to sun protection oil lotion could be used as reservoir for replacing UV photo degraded vitamin E. In the research, the vitamin E absorption capacities of zeolite microparticles of concentration of 0.2 % w/v in plant oil mixture (Olea Europea Oil, Sunflower oil) have been studied by UV-Vis spectrophotometry. The sedimentation and laser diffraction measurements gave broad distribution on size of the zeolite microparticles (1 μm to 15 μm) without interparticle interactions in the solution. The results showed ten-fold decrease in UV absorbance at wavelength of 292 nm in the first 30 minutes of vitamin E absorption to zeolite microparticles and a flat of release in the sunscreen lotion. (Author)

A randomized intervention study of sun protection promotion in well-child care.

Science.gov (United States)

Crane, Lori A; Deas, Ann; Mokrohisky, Stefan T; Ehrsam, Gretchen; Jones, Richard H; Dellavalle, Robert; Byers, Tim E; Morelli, Joseph

2006-03-01

This study evaluated the behavioral impact of a skin cancer prevention program in which health care providers delivered advice and materials to parents of infants over a 3-year period from 1998 to 2001. Fourteen offices of a large managed care organization in Colorado were randomly assigned to the intervention or control groups. 728 infants and their parents were recruited within 6 months of birth. At intervention offices, health care providers attended orientation sessions, prompts for delivering sun protection advice were placed in medical records, and parents received sun protection packets at each well-child visit between 2 and 36 months of age. Based on provider self-report and exit interviews of parents, providers in the intervention group delivered approximately twice as much sun protection advice as providers in the control group. Annual telephone interviews of parents indicated small but statistically significant differences in parent sun protection practices favoring the intervention. Skin exams revealed no significant differences in tanning, freckling, or number of nevi. Behavioral differences between groups appeared to grow over the 3 years of follow-up. This intervention strategy was successful in increasing the delivery of sun protection advice by health care providers and resulted in changes in parents' behaviors. While the behavioral effect was probably not strong enough to reduce risk for skin cancer, the effect may increase as children age and have more opportunities for overexposure to the sun.

Hand protection from ultraviolet exposure

International Nuclear Information System (INIS)

Khazova, M.; O'Hagan, J.B.

2006-01-01

Full text of publication follows: A number of industrial applications and public services involve exposure to ultraviolet radiation (U.V.R.) from a variety of lamps and lasers, for example, in forensic examination, biological trans-illuminators, dentistry, laser material processing, microelectronics, etc. The proposed European Union Directive on Optical Radiation would place specific requirements on employers to provide adequate safety measures to reduce exposure to U.V.R., including gloves for hand protection. The selection of gloves should be based on a risk assessment and on the performance characteristics of the gloves for the task. However, current International and national standards do not describe evaluation procedures of disposable gloves for hand protection against non-ionising radiation. A methodology for assessment of the UV protection level for disposable gloves and a simple measurement protocol are proposed, based on a common approach with UV protection by clothing and sunscreens. Glove Ultraviolet Protection Factor is defined as a time-scale increase in exposure permitted for the hand protected by a glove with respect to an unprotected hand. However, the wide variety of U.V.R. sources and the real-life conditions of glove use (stretching and wetting the surface by liquids) bring substantial challenges to the assessment method. Our study of ∼ 50 samples of widely used disposable gloves made of different materials (nitrile, vinyl, latex and chloroprene) showed that for all tested gloves a change in U.V.R. attenuation with stretching is characteristic for the type of glove material and can be included as a scaling factor in the definition of U.V.R. protection. Glove material has a bigger effect on U.V.R. protection level than variations in the glove thickness or its colour. The following approaches are suggested to overcome the problem of variable U.V.R. sources: - Worst case scenario minimal protection level, most restrictive case - Application

Hand protection from ultraviolet exposure

Energy Technology Data Exchange (ETDEWEB)

Khazova, M.; O' Hagan, J.B. [Health Protection Agency, Radiation Protection Division, Chilton, Did cot (United Kingdom)

2006-07-01

Full text of publication follows: A number of industrial applications and public services involve exposure to ultraviolet radiation (U.V.R.) from a variety of lamps and lasers, for example, in forensic examination, biological trans-illuminators, dentistry, laser material processing, microelectronics, etc. The proposed European Union Directive on Optical Radiation would place specific requirements on employers to provide adequate safety measures to reduce exposure to U.V.R., including gloves for hand protection. The selection of gloves should be based on a risk assessment and on the performance characteristics of the gloves for the task. However, current International and national standards do not describe evaluation procedures of disposable gloves for hand protection against non-ionising radiation. A methodology for assessment of the UV protection level for disposable gloves and a simple measurement protocol are proposed, based on a common approach with UV protection by clothing and sunscreens. Glove Ultraviolet Protection Factor is defined as a time-scale increase in exposure permitted for the hand protected by a glove with respect to an unprotected hand. However, the wide variety of U.V.R. sources and the real-life conditions of glove use (stretching and wetting the surface by liquids) bring substantial challenges to the assessment method. Our study of {approx} 50 samples of widely used disposable gloves made of different materials (nitrile, vinyl, latex and chloroprene) showed that for all tested gloves a change in U.V.R. attenuation with stretching is characteristic for the type of glove material and can be included as a scaling factor in the definition of U.V.R. protection. Glove material has a bigger effect on U.V.R. protection level than variations in the glove thickness or its colour. The following approaches are suggested to overcome the problem of variable U.V.R. sources: - Worst case scenario minimal protection level, most restrictive case - Application

Local biodiversity is higher inside than outside terrestrial protected areas worldwide

Science.gov (United States)

Gray, Claudia L.; Hill, Samantha L. L.; Newbold, Tim; Hudson, Lawrence N.; Börger, Luca; Contu, Sara; Hoskins, Andrew J.; Ferrier, Simon; Purvis, Andy; Scharlemann, Jörn P. W.

2016-01-01

Protected areas are widely considered essential for biodiversity conservation. However, few global studies have demonstrated that protection benefits a broad range of species. Here, using a new global biodiversity database with unprecedented geographic and taxonomic coverage, we compare four biodiversity measures at sites sampled in multiple land uses inside and outside protected areas. Globally, species richness is 10.6% higher and abundance 14.5% higher in samples taken inside protected areas compared with samples taken outside, but neither rarefaction-based richness nor endemicity differ significantly. Importantly, we show that the positive effects of protection are mostly attributable to differences in land use between protected and unprotected sites. Nonetheless, even within some human-dominated land uses, species richness and abundance are higher in protected sites. Our results reinforce the global importance of protected areas but suggest that protection does not consistently benefit species with small ranges or increase the variety of ecological niches. PMID:27465407

Growth Hormone Protects the Intestine Preserving Radiotherapy Efficacy on Tumors: A Short-Term Study.

Directory of Open Access Journals (Sweden)

Victor Caz

Full Text Available The efficacy of radiotherapy on tumors is hampered by its devastating adverse effects on healthy tissue, particularly that of the gastrointestinal tract. These effects cause acute symptoms that are so disruptive to patients that they can lead to interruption of the radiotherapy program. These adverse effects could limit the intensity of radiation received by the patient, resulting in a sublethal dose to the tumor, thus increasing the risk of tumor resistance. The lack of an effective treatment to protect the bowel during radiation therapy to allow higher radiation doses that are lethal to the tumor has become a barrier to implementing effective therapy. In this study, we present a comparative analysis of both intestinal and tumor tissue in regard to the efficacy and the preventive impact of a short-term growth hormone (GH treatment in tumor-bearing rats as a protective agent during radiotherapy. Our data show that the exogenous administration of GH improved intestinal recovery after radiation treatment while preserving the therapeutic effect against the tumor. GH significantly increased proliferation in the irradiated intestine but not in the irradiated tumors, as assessed by Positron Emission Tomography and the proliferative markers Ki67, cyclin D3, and Proliferating Cell Nuclear Antigen. This proliferative effect was consistent with a significant increase in irradiated intestinal villi and crypt length. Furthermore, GH significantly decreased caspase-3 activity in the intestine, whereas GH did not produce this effect in the irradiated tumors. In conclusion, short-term GH treatment protects the bowel, inducing proliferation while reducing apoptosis in healthy intestinal tissue and preserving radiotherapy efficacy on tumors.

Does a 'protective' message reduce the impact of an advergame promoting unhealthy foods to children? An experimental study in Spain and The Netherlands.

Science.gov (United States)

Folkvord, Frans; Lupiáñez-Villanueva, Francisco; Codagnone, Cristiano; Bogliacino, Francesco; Veltri, Giuseppe; Gaskell, George

2017-05-01

The weight of evidence points to the advertising of food affecting food consumption, especially among children. Such advertising often promotes unhealthy foods. Current policy deliberations focus on developing effective 'protective' messages to increase advertising literacy and consequent scepticism about advertising targeting children. This study examined whether incorporating a 'protective' message in an advergame promoting energy-dense snacks would reduce children's snack intake. A randomized between-subject design was conducted in the Netherlands (N = 215) and Spain (N = 382) with an advergame promoting either energy-dense snacks or nonfood products. The results showed that playing an advergame promoting energy-dense snacks increased caloric intake in both countries, irrespective of whether the 'protective' message was present or not. These results point to the limitations of 'protective' messages and advertising literacy and provide policy makers with a rationale for extending the current prohibition of food advertising to young children in the terrestrial media to online environments. Copyright © 2017 Elsevier Ltd. All rights reserved.

EXPERT SYSTEMS SHOW PROMISE FOR CUSTOMER INQUIRIES

Science.gov (United States)

This article describes results of an agreement between the North Penn Water Authority in Lansdale, Pa., and the US Environmental Protection Agency, Drinking Water Research Division, Cincinnati, Ohio, to study use of expert systems technology in a water utility. The threeyear stud...

Evaluation of cross-protection of bluetongue virus serotype 4 with other serotypes in sheep

Directory of Open Access Journals (Sweden)

Gcwalisile B. Zulu

2014-10-01

Full Text Available Bluetongue (BT is a non-contagious disease of sheep and other domestic and wild ruminants caused by the bluetongue virus (BTV. Currently 26 serotypes of the virus have been identified. In South Africa, 22 serotypes have been identified and BT is controlled mainly by annual vaccinations using a freeze-dried live attenuated polyvalent BTV vaccine. The vaccine is constituted of 15 BTV serotypes divided into three separate bottles and the aim is to develop a vaccine using fewer serotypes without compromising the immunity against the disease. This study is based on previously reported cross-neutralisation of specific BTV serotypes in in vitro studies. Bluetongue virus serotype 4 was selected for this trial and was tested for cross-protection against serotype 4 (control, 1 (unrelated serotype, 9, 10 and 11 in sheep using the serum neutralisation test. The purpose of the study was to determine possible cross-protection of different serotypes in sheep. Of those vaccinated with BTV-4 and challenged with BTV-1, which is not directly related to BTV-4, 20% were completely protected and 80% showed clinical signs, but the reaction was not as severe as amongst the unvaccinated animals. In the group challenged with BTV-10, some showed good protection and some became very sick. Those challenged with BTV-9 and BTV-11 had good protection. The results showed that BTV-4 does not only elicit a specific immune response but can also protect against other serotypes.

Microprocessor Protection of Power Reducing Transformers

OpenAIRE

F. A. Romanuk; S. P. Korolev; M. S. Loman

2011-01-01

The paper contains analysis of advantages and disadvantages of existing differential protection terminals of power reducing transformers. The paper shows that there are good reasons to develop microprocessor protection of power reducing transformer which contains required functions and settings and which is based on Belarusian principles of relay protection system construction. The paper presents functional structure of microprocessor terminal of power reducing transformer which is developed. 

Protective agents used as additives in University of Wisconsin solution to promote protection against ischaemia-reperfusion injury in rat lung.

Science.gov (United States)

Chiang, C H; Wu, K; Yu, C P; Perng, W C; Yan, H C; Wu, C P; Chang, D M; Hsu, K

1998-09-01

1. An intervention to reduce ischaemia-reperfusion lung injury will be an important advance in transplant medicine. Although the mechanisms associated with producing ischaemia-reperfusion endothelial injury have not been completely elucidated, many of the injury mediators have been studied in detail. While no single pharmacological therapy is likely to be totally effective in eliminating this complex injury, we have developed a mixture of agents that are known to block pathways involved in producing ischaemia-reperfusion-associated lung vascular injury.2. The present study modified University of Wisconsin solution (UW) by adding one of the protective agents prostaglandin E1 (PGE1), dexamethasone (Dex) or dibutyryl cAMP (Bt2-cAMP), or a combination of these, to the perfusate of rat lungs exposed to 4 h of cold ischaemia followed by 1 h of reperfusion. Nine modified UW solutions were studied: (1) UW+Dex, (2) UW+PGE1, (3) UW+Bt2-cAMP, (4) UW+Dexx3, (5) UW+PGE1x3, (6) UW+Bt2-cAMPx3, (7) UW+Dex+PGE1, (8) UW+Dex+Bt2-cAMP, (9) UW+PGE1+Bt2-cAMP. These solutions were utilized in individual experiments to assess haemodynamic changes, lung weight gain, the capillary filtration coefficient (Kfc) and pathology in all lungs.3. The results indicate that lung weight gain and Kfc values were significantly lower than with UW alone in groups 1, 2 and 3, which contained only one additional protective agent. In groups 4, 5 and 6, which contain three times the concentration of each protective agent, both Kfc and lung weight gain were similar to those measured in groups 1, 2 and 3, i.e. lungs were protected but the protection was not dose dependent. In groups 7, 8 and 9, which contained two protective agents, lung weight gain and Kfc were greatly reduced compared with UW alone. Histopathological studies showed similar decreases in the injury profiles of lungs.4. Although UW contains several antioxidant protective agents such as allopurinol and glutathione, it did not provide effective

Can Nature Protection be Unsustainable? Models Behind Nature Protection in New Zealands National Parks

Science.gov (United States)

Hauhs, Michael; Bogner, Christina

2013-04-01

Nature protection can be justified by intrinsic values of life. Western culture sees nature as an autonomous system. Thus, nature protection is often synonymous with refraining from human interference as much as possible. This, however, can pose at least technical problems. Indeed, historical human impacts such as introduced species are often irreversible. In such cases refraining from human interference to protect threatened species is not an adequate management response. Nature protection in New Zealand is a prominent example. Many introduced species make a non-interventionist attitude infeasible to protect endemic species such as kiwis. Actually, active human interference is necessary to attain this goal. Therefore, one may consider nature protection as another form of land use. As any other form of land use, it needs standards of proper management (i.e. explicit goals, assessment, intervention etc.). In other words, it has to be shown to be sustainable. However, sustainability may rigorously be defined as an attribute of past land use only. Instantaneous positive indicators of sustainability may be elusive. At best it can be decided by observation whether or not a land use has been (not) sustainable until now. Stakeholders of nature protection have often different (implicit) concepts or models of nature in mind. This can lead to conflicts when it comes to management decisions. For example, the methods by which conservationists in New Zealand seek to re-establish historical species assemblages (e.g. aerial drop of poison into national parks) have come under criticism of animal rights groups as non-humane. We propose to use abstract modelling language to classify these concepts of nature protection and related issues. We show that from modelling perspective these conflicts pose a basic science problem rather than an applied science problem. This makes the delegation into existing disciplines so hard. We discuss possible implications for nature protection

Health and radiation protection management

International Nuclear Information System (INIS)

Huhn, A.; Vargas, M.; Lorenzetti, J.; Lança, L.

2017-01-01

Quality management and continuous improvement systems are becoming part of daily health services, including radiodiagnostic services, which are designed to meet the needs of users, operating in an environment where the differential is due to the competence and quality of the services provided. The objective of this study is to show the scope of the management of health services, especially radiodiagnosis and radiological protection. Method: Exploratory and descriptive study, based on a review of the literature on the subject. Results: Radiodiagnosis has demonstrated the need for efficient management, especially because ionizing radiation is present in this environment and it is imperative that the professionals working in this area are aware of the need to perform adequate radiological protection for themselves and for users. Conclusion: Universal access to information has changed the attitude of the user and the user has become more demanding in his choices, wanting to understand, express, interact and choose the best quality service in view of the various options available in the market

Overvoltage Protection of Large Power Transformers - A Real-Life Study Case

DEFF Research Database (Denmark)

Bak, Claus Leth; Einarsdottir, K. E.; Andresson, E.

2008-01-01

This paper demonstrates the results from a detailed study of the overvoltage protection of a particular 400/150-kV 400-MVA power transformer. The work presented here is based on a real-life power system substation design and data and initiated by Danish TSO Energinet.dk as a consequence of serious...... transformer overvoltage damage. A simulation model for the entire system consisting of overhead line, transformer, surge arrester, and earth grid has been created in PSCAD/EMTDC. The main focus has been put on the earth grid, which has been submodeled in detail in MATLAB using an electromagnetic transient...... exceeded. It is clearly illustrated that the transient performance of the earth grid plays an important role in the overall overvoltage protection system design....

Data Protection Governance, Risk Management, and Compliance

CERN Document Server

Hill, David G

2009-01-01

Explains how to gain a handle on the vital aspects of data protection, offering an understanding of how data protection fits into various organizations. This book shows how to improve the data protection process through the high-level PRO-Tech model. It covers other topics including data retention, data security and eDiscovery.

Adaptive protection scheme

Directory of Open Access Journals (Sweden)

R. Sitharthan

2016-09-01

Full Text Available This paper aims at modelling an electronically coupled distributed energy resource with an adaptive protection scheme. The electronically coupled distributed energy resource is a microgrid framework formed by coupling the renewable energy source electronically. Further, the proposed adaptive protection scheme provides a suitable protection to the microgrid for various fault conditions irrespective of the operating mode of the microgrid: namely, grid connected mode and islanded mode. The outstanding aspect of the developed adaptive protection scheme is that it monitors the microgrid and instantly updates relay fault current according to the variations that occur in the system. The proposed adaptive protection scheme also employs auto reclosures, through which the proposed adaptive protection scheme recovers faster from the fault and thereby increases the consistency of the microgrid. The effectiveness of the proposed adaptive protection is studied through the time domain simulations carried out in the PSCAD⧹EMTDC software environment.

Quench Protection Studies of 11T Nb$_3$Sn Dipole Models for LHC Upgrades

Energy Technology Data Exchange (ETDEWEB)

Zlobin, Alexander [Fermilab; Chlachidze, Guram [Fermilab; Nobrega, Alfred [Fermilab; Novitski, Igor [Fermilab; Karppinen, Mikko [CERN

2014-07-01

CERN and FNAL are developing 11 T Nb3Sn dipole magnets for the LHC collimation system upgrade. Due to the large stored energy, protection of these magnets during a quench is a challenging problem. This paper reports the results of experimental studies of key quench protection parameters including longitudinal and radial quench propagation in the coil, coil heating due to a quench, and energy extraction and quench-back effect. The studies were performed using a 1 m long 11 T Nb3Sn dipole coil tested in a magnetic mirror configuration.

Study on countermeasures for effective assessment of domestic system of physical protection

International Nuclear Information System (INIS)

Lee, Jong Uk; An, J. S.; Min, G. S.; Yoon, W. K.; Kim, K. J.; Kim, J. K.; Lim, J. H.; Choe, K. K.; Park, S. G.

2004-04-01

Since the threat for nuclear facilities has increased due to the collapse of the Soviet Union and the allegations of Iraq and North Korean nuclear programmes, the concern for international regime of physical protection has been a hot issue worldwide. In addition, as the international strengthening trend of physical protection had been speeded up since the September 11th terror, Member States including the IAEA had agreed to revise the CPPNM(INFCIRC/274/rev.1) and prepared a draft amendment of CPPNM to establish their systems of physical protection based on threat assessment. However, Korean government has not yet established the domestic regime of threat assessment as well as national DBT for nuclear facilities, so it is very urgent to prepare the measures for them. As a domestic countermeasure for the international trend, Korean government promulgated a new 'Law for Physical Protection and Radiological Emergency'(LPPRE) on May 2003, which was based on establishing the regime of threat assessment, but it is necessary for us to construct the substantial countermeasures for its implementation as well as to legislate the following regulations of the LPPRE. Therefore, this study suggests the measures for constructing domestic regime of threat assessment in order to establish the legal and institutional framework and provides the efficient countermeasures for its implementation

Anion embedded sol-gel films on Al for corrosion protection

International Nuclear Information System (INIS)

Sheffer, Mari; Groysman, Alec; Starosvetsky, David; Savchenko, Natali; Mandler, Daniel

2004-01-01

We report here on the successful incorporation of organic anions into a sol-gel film on Al as a means of enhancing the protection against corrosion. Following our previous study where we showed that hydrophobic sol-gel films provided pronounced corrosion inhibition, we studied the corrosion inhibition that phenylphosphonic acid (PPA) has when embedded inside a thin sol-gel coating on Al. The anion of this organic anion tends to stay inside a phenyltrimethoxysilane (PTMOS) based sol-gel film due to π-interactions. Our findings, which are derived primarily from potentiodynamic polarization measurements, electrochemical noise, scanning electron microscopy measurements and Auger electron spectroscopy (AES), clearly show that the organic phosphonate adds to the protection efficiency of the sol-gel film

Promotion of sun protective behaviors in high school students in Ahwaz: a theory-based intervention

Directory of Open Access Journals (Sweden)

Heydar Rahmati Asl

2017-07-01

Full Text Available The most important environmental factor affecting human health is the long exposure to solar ultraviolet radiation. This study aimed to determine the effect of an educational intervention based on the protection motivation theory in promoting sun-protective behaviors. In this quasi-experimental prepost test study, a sample of 215 high school students in Ahwaz. Using a reliable and valid questionnaire, and based on the theory of protection motivation, the data were collected before and four months after the intervention. In the posttest, there was a significant difference in mean score of the protection motivation theory components between the experimental and control groups. the comparison of the mean score of the components of protection motivation theory in the experimental and control groups before and after the intervention showed a significant difference in all the components except for the response cost, while in the control group the mean score difference not significant. The results of this study showed that the intervention may lead to the sun exposure preventive behaviors, which reflects the effectiveness of the educational intervention based on the protection motivation theory.

Study of ion plating parameters, coating structure, and corrosion protection for aluminum coatings on uranium

International Nuclear Information System (INIS)

Egert, C.M.; Scott, D.G.

1987-01-01

A study of ion-plating parameters (primarily deposition rate and substrate bias voltage), coating structure, and the corrosion protection provided by aluminum coatings on uranium is presented. Ion plating at low temperatures yields a variety of aluminum coating structures on uranium. For example, aluminum coatings produced at high deposition rates and low substrate bias voltages are columnar with voids between columns, as expected for high-rate vapor deposition at low temperatures. On the other hand, low deposition rate and high bias voltage produce a modified coating with a dense, noncolumnar structure. These results are not in agreement with other studies that have found no relationship between deposition rate and coating structure in ion plating. This discrepancy is probably due to the high deposition rates used in these studies. An accelerated, water vapor corrosion test indicates that the columnar aluminum coatings provide some corrosion protection despite their porous nature; however, the dense noncolumnar coatings provide significantly greater protection. These results indicate that ion-plated aluminum coatings produced at low deposition rates and high substrate bias voltages creates dense coating structures that are most effective in protecting uranium from corrosion

Distance Protection for Microgrids in Distribution System

DEFF Research Database (Denmark)

Lin, Hengwei; Liu, Chengxi; Guerrero, Josep M.

2015-01-01

protection decreased. This paper adopts distance protection for one mid-voltage level microgrid in Aalborg, Denmark. Different operation modes of the network are analyzed and tested in the paper. The simulation results show that the variations of the fault currents seen by the forward relays are much larger...... than the backward relays. Meanwhile, the fault currents change little with the randomness of renewable energy except the intermittence. Finally, it shows that the designed distance protection has satisfactory performance to clear the various faults.......Owing to the increasing penetration of distributed generation, there are some challenges for the conventional protection in distribution system. Bidirectional power flow and variable fault current because of the various operation modes may lead to the selectivity and sensitivity of the overcurrent...

Microprocessor Protection of Power Reducing Transformers

Directory of Open Access Journals (Sweden)

F. A. Romanuk

2011-01-01

Full Text Available The paper contains analysis of advantages and disadvantages of existing differential protection terminals of power reducing transformers. The paper shows that there are good reasons to develop microprocessor protection of power reducing transformer which contains required functions and settings and which is based on Belarusian principles of relay protection system construction. The paper presents functional structure of microprocessor terminal of power reducing transformer which is developed. 

Studies on Coloration and UV Protective Action of Anar Peel (Pomegranate Rind) as an Effective Natural Colorant for Cotton Khadi Fabric

Science.gov (United States)

Sinnur, H. D.; Samanta, Ashis Kumar; Verma, D. K.; Kaware, Runali

2018-06-01

Besides optimization of conditions of colour extraction from dried anar peel, effect of different single and double mordants, dyeing process variables and UV protective action of anar peels (pomegranate rind i.e. Punica granatum L.) as a natural colourant is studied in this work. Mordants used are potash alum, aluminium sulphate and stannous chloride (as metallic salt mordant) and harda (i.e., myrobolan as natural mordant) from natural source. Relevant results indicate that 50:50 ratio of harda plus potash aluminium sulphate at overall 15% application level offers maximum K/S value and overall good colour fastness than any other combination. After finalizing the mordants, dyeing process variables were studied for standardization of conditions for dyeing cotton khadi fabric with aqueous extract of pomegranate rind. The results indicate that standardized conditions for dyeing are (a) dyeing time : 60 min, (b) dyeing temperature: 80 °C, (c) dye bath MLR : 1:30, (d) dye bath pH : 9.0, (e) max dye concentration : 20% and (f) common salt : 3%. Studies of FTIR, UV scan, Atomic Absorption Spectrophotometry (AAS) and UV Protection Factor (UPF) characters show a medium to good level of ultraviolet protection. Corresponding reaction mechanism amongst mordant/fibre and dye forming giant complex is also reported.

Studies on Coloration and UV Protective Action of Anar Peel (Pomegranate Rind) as an Effective Natural Colorant for Cotton Khadi Fabric

Science.gov (United States)

Sinnur, H. D.; Samanta, Ashis Kumar; Verma, D. K.; Kaware, Runali

2017-10-01

Besides optimization of conditions of colour extraction from dried anar peel, effect of different single and double mordants, dyeing process variables and UV protective action of anar peels (pomegranate rind i.e. Punica granatum L.) as a natural colourant is studied in this work. Mordants used are potash alum, aluminium sulphate and stannous chloride (as metallic salt mordant) and harda (i.e., myrobolan as natural mordant) from natural source. Relevant results indicate that 50:50 ratio of harda plus potash aluminium sulphate at overall 15% application level offers maximum K/S value and overall good colour fastness than any other combination. After finalizing the mordants, dyeing process variables were studied for standardization of conditions for dyeing cotton khadi fabric with aqueous extract of pomegranate rind. The results indicate that standardized conditions for dyeing are (a) dyeing time : 60 min, (b) dyeing temperature: 80 °C, (c) dye bath MLR : 1:30, (d) dye bath pH : 9.0, (e) max dye concentration : 20% and (f) common salt : 3%. Studies of FTIR, UV scan, Atomic Absorption Spectrophotometry (AAS) and UV Protection Factor (UPF) characters show a medium to good level of ultraviolet protection. Corresponding reaction mechanism amongst mordant/fibre and dye forming giant complex is also reported.

Decomposing inequality in financial protection situation in Iran after implementing the health reform plan: What does the evidence show based on national survey of households' budget?

Science.gov (United States)

Moradi, Tayebeh; Naghdi, Seyran; Brown, Heather; Ghiasvand, Hesam; Mobinizadeh, Mohammadreza

2018-03-24

Lack of well-designed healthcare financing mechanisms and high level of out-of-pocket payments in Iran over the last decades led to implementing Health Transformation Plan, in 2014. This study aims to decompose inequality in financial protection of Iranian households after the implementation of the Health Transformation Plan. The data of Statistical Center of Iran (SCI) Survey on Rural and Urban Households Income-Expenditure in 2015 to 2016 were used. The headcount ratio of catastrophic health expenditures was calculated. The corrected concentration index was estimated. The role of contributors on inequality in the exposure to catastrophic health expenditures among poor and nonpoor households was calculated using Farelie's model. The headcount ratio of the exposure to catastrophic health expenditures in urban and rural households was 4.58% and 5.65%, respectively. The difference in households' income levels was the main contributor in explaining the inequality in facing catastrophic health expenditures between poor and nonpoor households. Even after implementing the HTP, the headcount ratios of catastrophic health expenditure are still considerable. The results show that income is the greatest determinant of inequality in facing catastrophic health expenditure and in urban households. Copyright © 2018 John Wiley & Sons, Ltd.

Complete rerouting protection

DEFF Research Database (Denmark)

Stidsen, Thomas K.; Kjærulff, Peter

2006-01-01

Protection of communication against network failures is becoming increasingly important and in this paper we present the most capacity efficient protection method possible, the complete rerouting protection method, when requiring that all communication should be restored in case of a single link...... network failure. We present a linear programming model of the protection method and a column generation algorithm. For 6 real world networks, the minimal restoration overbuild network capacity is between 13% and 78%. We further study the importance of the density of the network, derive analytical bounds...

protective relay studies for the nigerian national electric 330 kv

African Journals Online (AJOL)

user

1985-09-01

Sep 1, 1985 ... protective relay schemes of the National Electric Power Authority. Some of the basic ... Nigerian special system characteristics, schemes to correct existing protection inadequacies .... relays buried in the transformer. A reach of ...

Medical social work practice in child protection in China: A multiple case study in Shanghai hospitals.

Science.gov (United States)

Zhao, Fang; Hämäläinen, Juha; Chen, Yu-Ting

2017-01-01

With the rapid development of the child welfare system in China over recent years, medical social work has been increasingly involved in providing child protection services in several hospitals in Shanghai. Focusing on five cases in this paper, the exploratory study aims to present a critical overview of current practices and effects of medical social work for child protection, based on a critical analysis of the multidimensional role of social work practitioners engaged in the provision of child protection services as well as potential challenges. Implications and suggestions for future improvements of China's child protection system are also discussed.

Adaptive Distance Protection for Microgrids

DEFF Research Database (Denmark)

Lin, Hengwei; Guerrero, Josep M.; Quintero, Juan Carlos Vasquez

2015-01-01

is adopted to accelerate the tripping speed of the relays on the weak lines. The protection methodology is tested on a mid-voltage microgrid network in Aalborg, Denmark. The results show that the adaptive distance protection methodology has good selectivity and sensitivity. What is more, this system also has......Due to the increasing penetration of distributed generation resources, more and more microgrids can be found in distribution systems. This paper proposes a phasor measurement unit based distance protection strategy for microgrids in distribution system. At the same time, transfer tripping scheme...

The protective effect of Mucuna pruriens seeds against snake venom poisoning.

Science.gov (United States)

Tan, Nget Hong; Fung, Shin Yee; Sim, Si Mui; Marinello, Enrico; Guerranti, Roberto; Aguiyi, John C

2009-06-22

The seed, leaf and root of Mucuna pruriens have been used in traditional medicine for treatments of various diseases. In Nigeria, the seed is used as oral prophylactics for snakebite. To study the protective effects of Mucuna pruriens seed extract against the lethalities of various snake venoms. Rats were pre-treated with Mucuna pruriens seed extract and challenged with various snake venoms. The effectiveness of anti-Mucuna pruriens (anti-MPE) antibody to neutralize the lethalities of snake venoms was investigated by in vitro neutralization. In rats, MPE pre-treatment conferred effective protection against lethality of Naja sputatrix venom and moderate protection against Calloselasma rhodostoma venom. Indirect ELISA and immunoblotting studies showed that there were extensive cross-reactions between anti-MPE IgG and venoms from many different genera of poisonous snakes, suggesting the involvement of immunological neutralization in the protective effect of MPE pre-treatment against snake venom poisoning. In vitro neutralization experiments showed that the anti-MPE antibodies effectively neutralized the lethalities of Asiatic cobra (Naja) venoms, but were not very effective against other venoms tested. The anti-MPE antibodies could be used in the antiserum therapy of Asiatic cobra (Naja) bites.

Skin Protection Behaviors among Young Male Latino Day Laborers: An Exploratory Study Using a Social Cognitive Approach

Directory of Open Access Journals (Sweden)

Javier F. Boyas

2016-01-01

Full Text Available Latino Day Laborers (LDLs are employed in occupations where multiple work hazards exist. One such hazard is the overexposure to solar ultraviolet radiation for continuous periods of time. Regular sun exposure can put individuals at increased risk of developing skin cancers, especially without adequate protection. The purpose of this cross-sectional exploratory study was to use a social cognitive framework to assess skin protective behaviors among LDLs. A community-based nonrandom and purposive sample of LDLs was recruited in two states: Mississippi and Illinois. The study sample consisted of 137 male participants, of which the majority were of Mexican ancestry (72%. The average age was 35.40 (SD=9.89 years. Results demonstrated that a substantial number of LDLs do not adequately practice sun protection behaviors on a regular basis. The skin cancer knowledge scores were very modest. The most frequently indicated barriers towards sun protection were “inconvenient,” “forget to use,” and “not being able to reapply sunscreen.” Overall, LDLs had moderate confidence in their abilities to adopt successful sun protection strategies. This study underscores the need for intervention programs aimed at LDLs to reduce extended time in the sun and increase use of sun protective measures when working outdoors.

Human MTHFR-G1793A transition may be a protective mutation against male infertility: a genetic association study and in silico analysis.

Science.gov (United States)

Karimian, Mohammad; Hosseinzadeh Colagar, Abasalt

2018-06-01

In this paper, we evaluate the association of the human methylenetetrahydrofolate reductase (MTHFR)-G1793A transition with male infertility using a case-control study, a meta-analysis and an in silico analysis. In the case-control study, 308 blood samples (169 infertile and 139 fertile men) were collected. MTHFR-G1793A genotyping was performed by PCR-RFLP. The study revealed a significant protective association between the GA genotype (OR: 0.3737, 95%CI: 0.1874-0.7452, p = 0.0052) and A allele (OR: 0.4266, 95%CI: 0.2267-0.8030, p = 0.0083) with male infertility. Meta-analysis showed that the G1793A transition might be a protective mutation against male infertility in both A vs. G (OR: 0.608, 95%CI: 0.466-0.792, p silico-analysis revealed that although G1793A could not make fundamental changes in the function and structure of MTHFR, it could modify the structure of the mRNA (Distance =0.1809, p = 0.1095; p < 0.2 is significant). The results suggest that G1793A substitution might be a protective genetic factor against male infertility. However, further case-control studies are required to provide a more robust conclusion.

Optimal channel utilization and service protection in cellular communication systems

DEFF Research Database (Denmark)

Iversen, Villy Bæk

1997-01-01

In mobile communications an efficient utilization of the channels is of great importance.In this paper we consider the basic principles for obtaining the maximum utilization, and we study strategies for obtaining these limits.In general a high degree of sharing is efficient, but requires service...... protection mechanisms for protecting services and subscriber groups.We study cellular systems with overlaid cells, and the effect of overlapping cells, and we show that by dynamic channel allocation we obtain a high utilization.The models are generalizations of the Erlang-B formula, and can be evaluated...

Protecting count queries in study design.

Science.gov (United States)

Vinterbo, Staal A; Sarwate, Anand D; Boxwala, Aziz A

2012-01-01

Today's clinical research institutions provide tools for researchers to query their data warehouses for counts of patients. To protect patient privacy, counts are perturbed before reporting; this compromises their utility for increased privacy. The goal of this study is to extend current query answer systems to guarantee a quantifiable level of privacy and allow users to tailor perturbations to maximize the usefulness according to their needs. A perturbation mechanism was designed in which users are given options with respect to scale and direction of the perturbation. The mechanism translates the true count, user preferences, and a privacy level within administrator-specified bounds into a probability distribution from which the perturbed count is drawn. Users can significantly impact the scale and direction of the count perturbation and can receive more accurate final cohort estimates. Strong and semantically meaningful differential privacy is guaranteed, providing for a unified privacy accounting system that can support role-based trust levels. This study provides an open source web-enabled tool to investigate visually and numerically the interaction between system parameters, including required privacy level and user preference settings. Quantifying privacy allows system administrators to provide users with a privacy budget and to monitor its expenditure, enabling users to control the inevitable loss of utility. While current measures of privacy are conservative, this system can take advantage of future advances in privacy measurement. The system provides new ways of trading off privacy and utility that are not provided in current study design systems.

Mangroves can provide protection against wind damage during storms

Science.gov (United States)

Das, Saudamini; Crépin, Anne-Sophie

2013-12-01

Research has established that mangroves can protect lives and property from storms by buffering the impacts of storm surges. However, their effects in attenuating wind velocity and providing protection from wind damage during storms are not known. This study examined whether mangroves attenuate damage from cyclonic winds and found that they provide substantial protection to properties, even relatively far away from mangroves and the coast. We devised a theoretical model of wind protection by mangroves and calibrated and applied this model using data from the 1999 cyclone in the Odisha region of India. The model predicted and quantified the actual level of damage reasonably accurately and showed that mangroves reduced wind damage to houses. The wind protection value of mangroves in reducing house damage amounted to approximately US$177 per hectare at 1999 prices. This provides additional evidence of the storm protection ecosystem services that mangroves supply in the region and an additional reason to invest in mangrove ecosystems to provide better adaptability to coastal disasters such as storms.

Architecture and Fault Identification of Wide-area Protection System

Directory of Open Access Journals (Sweden)

Yuxue Wang

2012-09-01

Full Text Available Wide-area protection system (WAPS is widely studied for the purpose of improvng the performance of conventional backup protection. In this paper, the system architecture of WAPS is proposed and its key technologies are discussed in view of engineering projects. So a mixed structurecentralized-distributed structure which is more suitable for WAPS in limited power grid region, is obtained based on the advantages of the centralized structure and distributed structure. Furthermore, regional distance protection algorithm was taken as an example to illustrate the functions of the constituent units. Faulted components can be detected based on multi-source imformation fuse in the algorithm. And the algorithm cannot only improve the selectivity, the rapidity, and the reliability of relaying protection but also has high fault tolerant capability. A simulation of 220 kV grid systems in Easter Hubei province shows the effectiveness of the wide-area protection system presented by this paper.

Protection issues on microgrid/distributed generation based systems

Energy Technology Data Exchange (ETDEWEB)

Oliveira, Angelo R. [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET-MG), Belo Horizonte, MG (Brazil); Ribeiro, Paulo F. [Calvin College, Grand Rapids, MI (United States). Dept. of Electrical Engineering; Iung, Anderson M. [Geracao Paranapanema S.A., SP (Brazil). Duke Energy International. Market Analysis Dept.; Garcia, Paulo A.N. [Federal University of Juiz de Fora (UFJF), MG (Brazil). Dept. of Circuits

2009-07-01

This paper aims to discuss protection issues related to the presence of distributed generation (DG) in distribution systems. A case study is developed to show some impacts of transitions and operations with relay static settings to verify the reliability of systems in the presence of DG. (author)

Evapotranspiration studies for protective barriers: Experimental plans

International Nuclear Information System (INIS)

Link, S.O.; Waugh, W.J.

1989-11-01

This document describes a general theory and experimental plans for predicting evapotranspiration in support of the Protective Barrier Program. Evapotranspiration is the combined loss of water from plants and soil surfaces to the atmosphere. 45 refs., 1 fig., 4 tabs

Re-evaluation of a radiation protection cost benefit analysis study in brachytherapy

International Nuclear Information System (INIS)

Broek, J.G. van den; Weatherburn, H.

1994-01-01

This study investigates changes in the NRPB advice concerning cost benefit analysis over the last 10 years by correcting all figures for inflation and applying them to a particular radiation protection example, a previously published case of the introduction of afterloading brachytherapy equipment at the Christie Hospital, Manchester. It has been shown that for this example NRPB advice at one time led to a large cost benefit, at another time led to a large cost deficit and later still it again gives a large cost benefit. Application of cost benefit analysis to decision making in radiation protection is therefore shown to be in need of further investigation and clarification. (author)

Microbial contamination of contact lenses after scaling and root planing using ultrasonic scalers with and without protective eyewear: A clinical and microbiological study.

Science.gov (United States)

Afzha, Rooh; Chatterjee, Anirban; Subbaiah, Shobha Krishna; Pradeep, Avani Rangaraju

2016-01-01

Ultrasonic scaler is a preferential treatment modality among the clinicians. However, the aerosol/splatter generated is a concern for patients and practitioners. Therefore, the purpose of this study was to evaluate contamination of contact lenses of the dentist after scaling and root planing using ultrasonic scalers with and without protective eyewear. Thirty patients were randomly selected for scaling and root planing and divided into 2 groups of 15 each. Group A - dentist wearing contact lenses and protective eyewear. Group B - dentist wearing only contact lenses. After scaling and root planing using ultrasonic scalers, the lenses were subjected to culture and 16S rRNA (16S ribosomal RNA) gene sequencing. In Group A - 15 out of thirty samples were contaminated, in Group B - all the thirty samples were contaminated. Most of the samples showed Gram-positive bacteria and 5 samples were contaminated with fungi. 16S rRNA gene sequencing of forty contaminated samples showed that 31 were contaminated with Streptococcus mutans and 9 with Staphylococcus aureus. Keeping in mind the limitation of the study for the absence of negative control, we would like to conclude that dental practitioners should better avoid contact lenses in a dental setup because of the risk of contamination of the contact lenses from the various dental procedures which can produce aerosol/splatter and if worn, it is recommended to wear protective eyewear.

Mothers in methadone treatment and their involvement with the child protection system: a replication and extension study.

Science.gov (United States)

Taplin, Stephanie; Mattick, Richard P

2013-08-01

Although a high level of involvement with the child protection system has been identified in families where parental substance use is a feature, not all such parents abuse or neglect their children or have contact with the child protection system. Identifying parents with substance-use histories who are able to care for their children without intervention by the child protection system, and being able to target interventions to the families who need them the most is important. This study interviewed a relatively large sample of mothers about their histories, their children and their involvement with the child protection system. We hypothesized that mothers in opioid pharmacological treatment who are involved with child protection services are different in characteristics to those mothers who are not involved. One hundred and seventy-one women, with at least one child aged under 16 years, were interviewed at nine treatment clinics providing pharmacological treatment for opioid dependence across Sydney, Australia. Just over one-third of the women were involved with child protection services at the time of interview, mostly with children in out-of-home care. Logistic regression analyses revealed that factors which significantly increased the likelihood of the mother being involved with the child protection system were: (1) having a greater number of children, (2) being on psychiatric medication, and (3) having less than daily contact with her own parents. This study replicates and extends the work of Grella, Hser, and Huang (2006) and the limited literature published to date examining the factors which contribute to some substance-using mothers becoming involved with the child protection system while others do not. The finding that mental health problems and parental supports (along with the number of children) were significantly associated with child protection system involvement in this study, indicates a need for improved interventions and the provision of

A new methodology for the assessment of hand protection from ultraviolet exposure.

Science.gov (United States)

Khazova, M; O'Hagan, J B; Grainger, K J-L

2006-01-01

A number of industrial applications and public services involve occupational exposure to ultraviolet radiation (UVR) from a variety of lamps and lasers. The aim of this study was to develop a methodology for the assessment of the UV protection level for disposable gloves. Glove UV protection factor is defined as a time-scale increase in exposure permitted for the hand protected by a glove with respect to an unprotected hand. Our study showed that for all tested gloves a change in UVR attenuation with stretching is characteristic for the type of glove material and can be included as a scaling factor in the definition of UVR protection. Glove material has a bigger effect on UVR protection level than variations in the glove thickness or its colour. Examples of assessment of the 'worst case scenario' are compared with the protection level against a number of sources, together with the guidance on a simplified evaluation protocol. An application-specific assessment, illustrated for 'SmartWater' forensic examinations and biological trans-illuminators, demonstrates that some gloves provide inadequate protection against occupational UV exposure.

Knowledge Protection and Input Complexity Arising from Open Innovation

DEFF Research Database (Denmark)

Peeters, Thijs; Sofka, Wolfgang

Controlling unique knowledge is of increasing importance to firms. Therefore, firms use knowledge protection mechanisms to prevent competitors from imitating their knowledge. We study the effects of the complexity of knowledge inputs that arises from open innovation on the importance of two widely...... used protection mechanisms: patents and trademarks. We argue that this complexity makes the threat of imitation less predictable, and thus makes knowledge protection more important. By analyzing survey data of 938 German firms, we find that patents are more important for firms in industries with higher...... knowledge input complexity. Furthermore, we show that the dynamics and not the level of knowledge input complexity positively affect the importance of trademarks....

A Study of the Protective Effect of Triticum aestivum L. in an Experimental Animal Model of Chronic Fatigue Syndrome.

Science.gov (United States)

Borah, Mukundam; Sarma, Phulen; Das, Swarnamoni

2014-10-01

Oxidative stress plays a major role in the pathogenesis of chronic fatigue syndrome (CFS). Keeping in view the proven antioxidant activity of Triticum aestivum L., this study has been undertaken to explore the potential therapeutic benefit of this plant in the treatment of CFS. To study the protective effect of the ethanolic extract of the leaves of Triticum aestivum (EETA) in an experimental mice model of CFS. Five groups of albino mice (20-25 g) were selected for the study, with five animals in each group. Group A served as the naïve control and Group B served as the stressed control. Groups C and D received EETA (100 mg/kg and 200 mg/kg b.w.). Group E received imipramine (20 mg/kg b.w.). Except for Group A, mice in each group were forced to swim 6 min each for 7 days to induce a state of chronic fatigue. Duration of immobility was measured on every alternate day. After 7 days, various behavioral tests (mirror chamber and elevated plus maize test for anxiety, open field test for locomotor activity) and biochemical estimations (malondialdehyde [MDA] and catalase activity) in mice brain were performed. Forced swimming in the stressed group resulted in a significant increase in immobility period, decrease in locomotor activity and elevated anxiety level. The brain homogenate showed significantly increased MDA and decreased catalase levels. The extract-treated groups showed significantly (P < 0.05) improved locomotor activity, decreased anxiety level, elevated catalase levels and reduction of MDA. The study confirms the protective effects of EETA in CFS.

Study of the protective effect of hydroalcoholic extract microemulsion of Teucrium polium .L against bromobenzene -induced hepatotoxicity in mice

Directory of Open Access Journals (Sweden)

alihasan Rahmani

2015-01-01

Full Text Available Background : Liver is a major organ of the body, which can be exposed to various chemicals, drugs and many other xenobiotics such as bromobenzene. The aim of this study was to find out the protective effect of hydroalcoholic extract microemulsion of Teucrium polium against hepatotoxicity induced by bromobenzene. Materials and Methods: Animals were divided into eight groups, with ten animals in each group. Group 1-3 received respectively normal saline base of microemulsion and extract microemulsions in dose of 400 mg/kg orally for 10 days. Group 4 received bromobenzene (0.36 ml/kg, ip only on the 10th day groups 5-8 received extract microemulsions orally in doses of 50, 100, 200 and 400 mg/kg respectively, during 10 days and bromobenzene (0.36 ml/kg, ip on the 10th day 1 hour after last dose of extract. 24 hours later, the animals were bled and enzymes ALT, AST and ALP were measured. Animal liver was removed for histological studies. Results: The results showed a significant increase in liver enzyme activity by bromobenzene. The treated groups with Teucrium polium showed a significant decrease in liver enzyme activity in doses of 100, 200 and 400 mg/kg (P<0.05. Histological observations also confirmed the results. Conclusion: The results revealed that hydroalcoholic extract microemulsion of Teucrium polium has protective effect on liver toxicity induced by bromobenzene

Information strategy and information products in radiation protection. A Norwegian RISKPERCOM study

Energy Technology Data Exchange (ETDEWEB)

Reitan, J B; Toennesen, A [Statens Straalevern, Oesteraas (Norway); Waldahl, R [Avdeling for media og kommunikasjon, Oslo Univ., Oslo (Norway)

1998-02-01

A short description of the national background for the radiation issue is presented together with a presentation of information strategy and analysis of the information products of the Norwegian Radiation Protection Authority. This is part of an international study. 35 refs.

Information strategy and information products in radiation protection. A Norwegian RISKPERCOM study

International Nuclear Information System (INIS)

Reitan, J.B.; Toennesen, A.; Waldahl, R.

1998-02-01

A short description of the national background for the radiation issue is presented together with a presentation of information strategy and analysis of the information products of the Norwegian Radiation Protection Authority. This is part of an international study. 35 refs

Protecting patron privacy

CERN Document Server

Beckstrom, Matthew

2015-01-01

In a world where almost anyone with computer savvy can hack, track, and record the online activities of others, your library can serve as a protected haven for your visitors who rely on the Internet to conduct research-if you take the necessary steps to safeguard their privacy. This book shows you how to protect patrons' privacy while using the technology that your library provides, including public computers, Internet access, wireless networks, and other devices. Logically organized into two major sections, the first part of the book discusses why the privacy of your users is of paramount

Studies on yttrium oxide coatings for corrosion protection against molten uranium

International Nuclear Information System (INIS)

Chakravarthy, Y.; Bhandari, Subhankar; Pragatheeswaran; Thiyagarajan, T.K.; Ananthapadmanabhan, P.V.; Das, A.K.; Kumar, Jay; Kutty, T.R.G.

2012-01-01

Yttrium oxide is resistant to corrosion by molten uranium and its alloys. Yttrium oxide is recommended as a protective oxide layer on graphite and metal components used for melting and processing uranium and its alloys. This paper presents studies on the efficacy of plasma sprayed yttrium oxide coatings for barrier applications against molten uranium

Functional recovery of denervated skeletal muscle with sensory or mixed nerve protection: a pilot study.

Directory of Open Access Journals (Sweden)

Qing Tian Li

Full Text Available Functional recovery is usually poor following peripheral nerve injury when reinnervation is delayed. Early innervation by sensory nerve has been indicated to prevent atrophy of the denervated muscle. It is hypothesized that early protection with sensory axons is adequate to improve functional recovery of skeletal muscle following prolonged denervation of mixed nerve injury. In this study, four groups of rats received surgical denervation of the tibial nerve. The proximal and distal stumps of the tibial nerve were ligated in all animals except for those in the immediate repair group. The experimental groups underwent denervation with nerve protection of peroneal nerve (mixed protection or sural nerve (sensory protection. The experimental and unprotected groups had a stage II surgery in which the trimmed proximal and distal tibial nerve stumps were sutured together. After 3 months of recovery, electrophysiological, histological and morphometric parameters were assessed. It was detected that the significant muscle atrophy and a good preserved structure of the muscle were observed in the unprotected and protective experimental groups, respectively. Significantly fewer numbers of regenerated myelinated axons were observed in the sensory-protected group. Enhanced recovery in the mixed protection group was indicated by the results of the muscle contraction force tests, regenerated myelinated fiber, and the results of the histological analysis. Our results suggest that early axons protection by mixed nerve may complement sensory axons which are required for promoting functional recovery of the denervated muscle natively innervated by mixed nerve.

Comparing fish communities in sanctuaries, partly protected areas ...

African Journals Online (AJOL)

Within coral-dominated reefs, abundances of indicator taxa showed three patterns: (1) greatest abundance in sanctuaries, intermediate in partly protected and least in open areas; (2) greatest abundance in sanctuaries but equal diminishment in partly protected and open areas; and (3) greater depletion in partly protected ...

Collective legal protection: The European approach

Directory of Open Access Journals (Sweden)

Petrušić Nevena

2014-01-01

Full Text Available One of the basic goals of the EU justice policy is to ensure an efficient and effective legal protection, particularly in cross-border disputes and cases concerning the violation of rights guaranteed under the EU legislation. In order to accomplish this goal, the EU embarked on a horizontal harmonization of civil procedure in some sectors and reinforced the institutional cooperation of Member States in the field of civil justice. Concurrently, there were some legal interventions in the field of civil procedure, which contributed to establishing a number of European procedural mechanisms, such as: the European Small Claims Procedure (2007, the European Payment Order Procedure (2006, etc. Many studies and analyses show that procedural mechanisms of collective legal protection are essential for ensuring an efficient and effective legal protection of rights guaranteed by the EU law. The idea of introducing the collective legal protection instruments into the EU law has been present for more than two decades. It has been endorsed by the European Economic and Social Committee, which has played the key role in its promotion. In June 2013, after extensive consultations, the European Commission adopted the Recommendation on common principles for injunctive and compensatory collective redress mechanisms in the Members States concerning violations of rights guaranteed under the EU law. This document has provided a coherent horizontal framework for the collective legal protection at the EU level by establishing the common European principles for collective redress mechanisms which the Member States should incorporate into their national systems. Analysis of the common principles governing the collective legal protection shows that the European approach to shaping the collective redress claims is significantly different from the American class action model, which is considered to be incompatible with the European legal tradition and deemed to provide a wide

Bonobos (Pan paniscus) show an attentional bias toward conspecifics' emotions.

Science.gov (United States)

Kret, Mariska E; Jaasma, Linda; Bionda, Thomas; Wijnen, Jasper G

2016-04-05

In social animals, the fast detection of group members' emotional expressions promotes swift and adequate responses, which is crucial for the maintenance of social bonds and ultimately for group survival. The dot-probe task is a well-established paradigm in psychology, measuring emotional attention through reaction times. Humans tend to be biased toward emotional images, especially when the emotion is of a threatening nature. Bonobos have rich, social emotional lives and are known for their soft and friendly character. In the present study, we investigated (i) whether bonobos, similar to humans, have an attentional bias toward emotional scenes compared with conspecifics showing a neutral expression, and (ii) which emotional behaviors attract their attention the most. As predicted, results consistently showed that bonobos' attention was biased toward the location of the emotional versus neutral scene. Interestingly, their attention was grabbed most by images showing conspecifics such as sexual behavior, yawning, or grooming, and not as much-as is often observed in humans-by signs of distress or aggression. The results suggest that protective and affiliative behaviors are pivotal in bonobo society and therefore attract immediate attention in this species.

[Radiation protection in interventional radiology].

Science.gov (United States)

Adamus, R; Loose, R; Wucherer, M; Uder, M; Galster, M

2016-03-01

The application of ionizing radiation in medicine seems to be a safe procedure for patients as well as for occupational exposition to personnel. The developments in interventional radiology with fluoroscopy and dose-intensive interventions require intensified radiation protection. It is recommended that all available tools should be used for this purpose. Besides the options for instruments, x‑ray protection at the intervention table must be intensively practiced with lead aprons and mounted lead glass. A special focus on eye protection to prevent cataracts is also recommended. The development of cataracts might no longer be deterministic, as confirmed by new data; therefore, the International Commission on Radiological Protection (ICRP) has lowered the threshold dose value for eyes from 150 mSv/year to 20 mSv/year. Measurements show that the new values can be achieved by applying all X‑ray protection measures plus lead-containing eyeglasses.

[Light protection: principles of UV protection].

Science.gov (United States)

Stege, H; Mang, R

2006-05-01

UV radiation is responsible for the induction of epithelial and melanocytic skin cancer, photoaging, and photodermatoses. UV protection is necessary to prevent damage caused by non-physiologic exposure. UV protection includes not only reduction of sun exposure but also use of sun protective filters, UV protective clothes, DNA repair enzymes, and antioxidant supplementation. Consumers are uncertain about the possibilities and limitations of commercial sun protection measures. Dermatologists must explain protective measures to the general public which continues to believe that UV-tanned skin is healthy. The sunscreen market is a highly competitive but lucrative market. The range of products with different designations and promises makes difficult for both consumers and dermatologists to determine what is sensible UV protection.

Feasibility study for a realistic training dedicated to radiological protection improvement

International Nuclear Information System (INIS)

Courageot, E.; Kutschera, R.; Gaillard-Lecanu, E.; Jahan, S.; Riedel, A.; Therache, B.

2013-01-01

An evident purpose of the radiological protection training is to use suitable protective equipment and to behave correctly if unexpected working conditions happen. A major difficulty of this training consist in having the most realistic reading from the monitoring devices for a given exposure situation, but without using real radioactive sources. A new approach is developed at EDF R/D for radiological protection training. This approach combines different technologies, in an environment representative of the workplace but geographically separated from the nuclear power plant: a training area representative of a workplace, a Man Machine Interface used by the trainer to define the source configuration and the training scenario, a geo-localization system, fictive radiation monitoring devices and a particle transport code able to calculate in real time the dose map due to the virtual sources. In a first approach, our real-time particles transport code, called Moderato, used only an attenuation low in straight line. To improve the realism further, we would like to switch a code based on the Monte Carlo transport of particles like Geant 4 or MCNPX instead of Moderato. The aim of our study is the evaluation of the code in our application, in particular, the possibility to keep a real time response of our architecture. (authors)

Study of protective effects of melatonin on cisplatin-induced nephrotoxicity in rabbits

International Nuclear Information System (INIS)

Aslam, J.; Khan, W.; Bakhtiar, S.

2017-01-01

To evaluate the protective effects of melatonin on cisplatin-induced nephrotoxicity in rabbits. Study Design: Laboratory based randomized control trial. Place and Duration of Study: Department of Pharmacology and Therapeutics in collaboration with Clinico Pathologic Laboratory, Army Medical College, Rawalpindi, from Apr to Jun 2015. Material and Methods: Eighteen rabbits were divided into three groups, each consisting of six rabbits. Baseline serum urea, creatinine, sodium and potassium were measured. Rabbits were weighed for dose calculation. A single dose of cisplatin 10mg/kg was given as I/P injection to the toxic group. The protective group received 5 mg/kg I/P melatonin for three days. Rabbits were sacrificed 72 hours after the cisplatin dose and both kidneys were sent for histopathology. Statistical analysis was carried out by using Microsoft Office Excel 2010 and SPSS version 21. Student's t-test and one way ANOVA, followed by 'Post Hoc Tukey' test was used for biochemical parameters, while Chi Square' test was used for histopathological comparison. Results: Moderate nephrotoxicity (grade-II) was seen in the toxic group, with substantial elevations of serum urea and creatinine (p<0.001), and serum sodium and potassium (p<0.01). Melatonin ameliorated the renal injury. Conclusion: The protective effects of melatonin on cisplatin-induced nephrotoxicity were due to its antioxidant properties. (author)

Advanced worker protection system

Energy Technology Data Exchange (ETDEWEB)

Caldwell, B.; Duncan, P.; Myers, J. [Oceaneering Space Systems, Houston, TX (United States)

1995-10-01

The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D&D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D&D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D&D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project describes the development of an Advanced Worker Protection System (AWPS) which will include a life-support backpack with liquid air for cooling and as a supply of breathing gas, protective clothing, respirators, communications, and support equipment.

Advanced worker protection system

International Nuclear Information System (INIS)

Caldwell, B.; Duncan, P.; Myers, J.

1995-01-01

The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D ampersand D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D ampersand D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D ampersand D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project describes the development of an Advanced Worker Protection System (AWPS) which will include a life-support backpack with liquid air for cooling and as a supply of breathing gas, protective clothing, respirators, communications, and support equipment

Performance study of protective clothing against hot water splashes: from bench scale test to instrumented manikin test.

Science.gov (United States)

Lu, Yehu; Song, Guowen; Wang, Faming

2015-03-01

Hot liquid hazards existing in work environments are shown to be a considerable risk for industrial workers. In this study, the predicted protection from fabric was assessed by a modified hot liquid splash tester. In these tests, conditions with and without an air spacer were applied. The protective performance of a garment exposed to hot water spray was investigated by a spray manikin evaluation system. Three-dimensional body scanning technique was used to characterize the air gap size between the protective clothing and the manikin skin. The relationship between bench scale test and manikin test was discussed and the regression model was established to predict the overall percentage of skin burn while wearing protective clothing. The results demonstrated strong correlations between bench scale test and manikin test. Based on these studies, the overall performance of protective clothing against hot water spray can be estimated on the basis of the results of the bench scale hot water splashes test and the information of air gap size entrapped in clothing. The findings provide effective guides for the design and material selection while developing high performance protective clothing. Published by Oxford University Press on behalf of the British Occupational Hygiene Society 2014.

Source Water Protection Planning for Ontario First Nations Communities: Case Studies Identifying Challenges and Outcomes

Directory of Open Access Journals (Sweden)

Leslie Collins

2017-07-01

Full Text Available After the Walkerton tragedy in 2000, where drinking water contamination left seven people dead and many suffering from chronic illness, the Province of Ontario, Canada implemented policies to develop Source Water Protection (SWP plans. Under the Clean Water Act (2006, thirty-six regional Conservation Authorities were mandated to develop watershed-based SWP plans under 19 Source Protection Regions. Most First Nations in Ontario are outside of these Source Protection Regions and reserve lands are under Federal jurisdiction. This paper explores how First Nations in Ontario are attempting to address SWP to improve drinking water quality in their communities even though these communities are not part of the Ontario SWP framework. The case studies highlight the gap between the regulatory requirements of the Federal and Provincial governments and the challenges for First Nations in Ontario from lack of funding to implement solutions to address the threats identified in SWP planning. This analysis of different approaches taken by Ontario First Nations shows that the Ontario framework for SWP planning is not an option for the majority of First Nations communities, and does not adequately address threats originating on reserve lands. First Nations attempting to address on-reserve threats to drinking water are using a variety of resources and approaches to develop community SWP plans. However, a common theme of all the cases surveyed is a lack of funding to support implementing solutions for the threats identified by the SWP planning process. Federal government initiatives to address the chronic problem of boil water advisories within Indigenous communities do not recognize SWP planning as a cost-effective tool for improving drinking water quality.

Physical protection evaluation methodology program development and application

International Nuclear Information System (INIS)

Seo, Janghoon; Yoo, Hosik

2015-01-01

It is essential to develop a reliable physical protection evaluation methodology for applying physical protection concept to the design stage. The methodology can be used to assess weak points and improve performance not only for the design stage but also for nuclear facilities in operation. Analyzing physical protection property of nuclear facilities is not a trivial work since there are many interconnected factors affecting overall performance. Therefore several international projects have been organized to develop a systematic physical protection evaluation methodology. INPRO (The International Project on Innovative Nuclear Reactors and Fuel Cycles) and GIF PRPP (Generation IV International Forum Proliferation Resistance and Physical Protection) methodology are among the most well-known evaluation methodologies. INPRO adopts a checklist type of questionnaire and has a strong point in analyzing overall characteristic of facilities in a qualitative way. COMPRE program has been developed to help general users apply COMPRE methodology to nuclear facilities. In this work, COMPRE program development and a case study of the hypothetical nuclear facility are presented. The development of COMPRE program and a case study for hypothetic facility is presented in this work. The case study shows that COMPRE PP methodology can be a useful tool to assess the overall physical protection performance of nuclear facilities. To obtain meaningful results from COMPRE PP methodology, detailed information and comprehensive analysis are required. Especially, it is not trivial to calculate reliable values for PPSE (Physical Protection System Effectiveness) and C (Consequence), while it is relatively straightforward to evaluate LI (Legislative and Institutional framework), MC (Material Control) and HR (Human Resources). To obtain a reliable PPSE value, comprehensive information about physical protection system, vital area analysis and realistic threat scenario assessment are required. Like

Physical protection evaluation methodology program development and application

Energy Technology Data Exchange (ETDEWEB)

Seo, Janghoon; Yoo, Hosik [Korea Institute of Nuclear Non-proliferation and Control, Daejeon (Korea, Republic of)

2015-10-15

It is essential to develop a reliable physical protection evaluation methodology for applying physical protection concept to the design stage. The methodology can be used to assess weak points and improve performance not only for the design stage but also for nuclear facilities in operation. Analyzing physical protection property of nuclear facilities is not a trivial work since there are many interconnected factors affecting overall performance. Therefore several international projects have been organized to develop a systematic physical protection evaluation methodology. INPRO (The International Project on Innovative Nuclear Reactors and Fuel Cycles) and GIF PRPP (Generation IV International Forum Proliferation Resistance and Physical Protection) methodology are among the most well-known evaluation methodologies. INPRO adopts a checklist type of questionnaire and has a strong point in analyzing overall characteristic of facilities in a qualitative way. COMPRE program has been developed to help general users apply COMPRE methodology to nuclear facilities. In this work, COMPRE program development and a case study of the hypothetical nuclear facility are presented. The development of COMPRE program and a case study for hypothetic facility is presented in this work. The case study shows that COMPRE PP methodology can be a useful tool to assess the overall physical protection performance of nuclear facilities. To obtain meaningful results from COMPRE PP methodology, detailed information and comprehensive analysis are required. Especially, it is not trivial to calculate reliable values for PPSE (Physical Protection System Effectiveness) and C (Consequence), while it is relatively straightforward to evaluate LI (Legislative and Institutional framework), MC (Material Control) and HR (Human Resources). To obtain a reliable PPSE value, comprehensive information about physical protection system, vital area analysis and realistic threat scenario assessment are required. Like

Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease.

Science.gov (United States)

Turner, Adam W; Martinuk, Amy; Silva, Anada; Lau, Paulina; Nikpay, Majid; Eriksson, Per; Folkersen, Lasse; Perisic, Ljubica; Hedin, Ulf; Soubeyrand, Sebastien; McPherson, Ruth

2016-05-01

A recent genome-wide association study meta-analysis identified an intronic single nucleotide polymorphism in SMAD3, rs56062135C>T, the minor allele (T) which associates with protection from coronary artery disease. Relevant to atherosclerosis, SMAD3 is a key contributor to transforming growth factor-β pathway signaling. Here, we seek to identify ≥1 causal coronary artery disease-associated single nucleotide polymorphisms at the SMAD3 locus and characterize mechanisms whereby the risk allele(s) contribute to coronary artery disease risk. By genetic and epigenetic fine mapping, we identified a candidate causal single nucleotide polymorphism rs17293632C>T (D', 0.97; r(2), 0.94 with rs56062135) in intron 1 of SMAD3 with predicted functional effects. We show that the sequence encompassing rs17293632 acts as a strong enhancer in human arterial smooth muscle cells. The common allele (C) preserves an activator protein (AP)-1 site and enhancer function, whereas the protective (T) allele disrupts the AP-1 site and significantly reduces enhancer activity (Pto the (C) allele. We show that rs17293632 is an expression quantitative trait locus for SMAD3 in blood and atherosclerotic plaque with reduced expression of SMAD3 in carriers of the protective allele. Finally, siRNA knockdown of SMAD3 in human arterial smooth muscle cells increases cell viability, consistent with an antiproliferative role. The coronary artery disease-associated rs17293632C>T single nucleotide polymorphism represents a novel functional cis-acting element at the SMAD3 locus. The protective (T) allele of rs17293632 disrupts a consensus AP-1 binding site in a SMAD3 intron 1 enhancer, reduces enhancer activity and SMAD3 expression, altering human arterial smooth muscle cell proliferation. © 2016 American Heart Association, Inc.

TOWARD DEVELOPMENT OF INSTITUTIONAL PROTECTION, REHABILITATUION OF HANDICAPPED PEOPLE IN MACEDONIA (basis for furtherer studies

Directory of Open Access Journals (Sweden)

Ljupco AJDINSKI

2000-12-01

Full Text Available This work gives an detailed review of the basic issues of development of protection and rehabilitation of handicapped people in Macedonia with data especially for the period pf the last five decades.A plentitude of documentary materials proved to be important starting assumption for further historical studies on protection and rehabilitation of handicapped people in the Republic of Macedonia.

Environmental protection

International Nuclear Information System (INIS)

Martinez, A.S.

1987-01-01

The question of environment protection related to the use of nuclear energy aiming to power generation, based on the harmonic concept of economic and industrial development, preserving the environment, is discussed. A brief study of environmental impacts for some energy sources, including nuclear energy, to present the systems of a nuclear power plant which aim at environmental protection, is done. (M.C.K.) [pt

Depth protection system

International Nuclear Information System (INIS)

Arita, Setsuo; Izumi, Shigeru; Suzuki, Satoru; Noguchi, Atomi.

1988-01-01

Purpose: To previously set a nuclear reactor toward safety side by the reactor scram if an emergency core cooling system is failed to operate. Constitution If abnormality occurs in an emergency core cooling system or an aqueous boric acid injection system, a reactor protection system is operated and, if the reactor protection system shows an abnormal state, a control rod withdrawal inhibition system is operated as a fundamental way. For instance, when the driving power source voltage for the emergency core cooling system is detected and, if it is lower than a predetermined value, the reactor protection system is operated. Alternatively, if the voltage goes lower than the predetermined value, the control rod withdrawal is inhibited. In addition, stopping for the feedwater system is inhibited. Further, integrity of the driving means for the emergency core cooling system is positively checked and the protection function is operated depending on the result of check. Since the nuclear reactor can be set toward the safety side even if the voltage for the driving power source of the aqueous boric acid injection system is lower than a predetermined value, the reactor safety can further be improved. (Horiuchi, T.)

Training in radiation protection

International Nuclear Information System (INIS)

Schreiber, F.

1998-01-01

Persons who are exposed to ionizing radiation at their workplace have to be trained in radiation protection. According to the Radiation Protection Ordinance the person with responsibility in radiation protection has to guarantee that the training is performed twice a year. Our training material was created especially for the persons defined in the Radiation Protection Ordinance and the X-ray Ordinance. It enables persons who teach (generally the radiation protection officer) to perform the training without tedious study and preparation of the documents. Our material is not just another textbook for radiation protection but rather a folder with colour transparencies and explanatory texts which make a difference in volume and price in comparison to other existing materials. (orig.) [de

Study of protective effect of Avicennia marina hydroethanolic leaf extract on testes tissue and spermatogenesis in male rat induced with carbon tetrachloride

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Z soleimani

2015-11-01

Full Text Available Aim: The toxic chemical compounds are widelyused in the world. Carbon tetrachloride which is used in hygiene industries caused tissue disorders. Medicinal plants have protective effects in body tissues. In this study the protective effect of Avicennia marina leaf extract (MLE on spermatogenesis in male rat were induced with ccl4 investigating. Method and materials: The 42 male rats with 220-250 gr body weight were divided randomly in 6 groups(n=7: control (taking normal saline,0.5ml/day, i,p , sham(taking olive oil, 0.5ml/day, i,p single dose,group induced by ccl4(carbon tetrachloride 1:1 with olive oil,0.5ml single dose, i,p, treated groups: (1,2 and3 by carbon tetrachloride 1:1 with olive oil,0.5ml single dose and 200mg/Kg, 400mg/Kg and 800mg/kg MLE /day for 96 hrs, i,p. After the examination the blood samples were collected from heart directly and testosterone , FSH, LH , sperm count, sperm motility and GSI were analyzed and the microscopic studies of testes tissue were done. All data were expressed as mean±SEM. and statistical significance differences were accepted at P<0.05. Results: Our results showed that the carbon tetrachloride has necrotic effect in testes. The number of sperm and motility were increased and microscopic study of testes tissue showed the necrosis and inflammation with decrease in spermatogonia and spermatocytes comparedwith ccl4 induced only group significantly (P<0.001 and treated groups were no changed. Conclusion: the Avicennia marina hydroethanolic extract has antioxidant and flavonoids compounds which can protect the testes tissues from toxic chemical agents.

Skin protective behavior amongst girl students; based on health belief model.

Directory of Open Access Journals (Sweden)

Ali Davati

2013-09-01

Full Text Available Skin cancer is the most prevalent type of cancer in most of the countries and more than 90% of cancer cases are related to ultra violet rays of the sun. Therefore protective behaviors against sunlight are considered the most essential measures for skin cancer prevention. This study has been conducted to determine the frequency of protective behavior against sunlight among female students of Tehran city high schools. The Health Belief Model has been used for this cross-sectional study to analyze the factors related to protective behaviors. A multi-phase sampling method was used. 941 female student of Tehran city high schools were studied using a probed question form. The data were then analyzed using SPSS software. During the study of protective behaviors against the sunlight, 24.7% of participants mentioned that they always use sunscreen. The behavior of using sunscreen is related to perceived sensitivity, severity and benefit amongst the students (P<0.05. Also 3.8% of the students who participated in our study were always using gloves in summer to protect against sunlight. The behavior of using gloves in summer was also related to perceived sensitivity, severity and benefit (P<0.05. Physicians were the most effective influencing people with 84.9% influence on the appropriate decision making by these students. There is a low frequency of protective behavior against sunlight among the female students of Tehran city high schools. These findings show the necessity of training the students in this regard and promote the protective behaviors amongst them.

Corrosion and protection in reinforced concrete : Pulse cathodic protection: an improved cost-effective alternative

NARCIS (Netherlands)

Koleva, D.A.

2007-01-01

Corrosion and protection in reinforced concrete. Pulse cathodic protection: an improved cost-effective alternative. The aim of the research project was to study the possibilities for establishing a new or improved electrochemical method for corrosion prevention/protection for reinforced concrete.

Assessment of Protective Effect of Some Modern Agrochemicals against Ozone-Induced Stress in Sensitive Clover and Tobacco Cultivars.

Science.gov (United States)

Blum, Oleg; Didyk, Nataliya; Pavluchenko, Nataliya; Godzik, Barbara

2011-01-01

Some modern agrochemicals with antioxidant potential were tested for their protective effect against ozone injury using clover and tobacco ozone-sensitive cultivars as model plants subjected to ambient ozone at two sites (Kyiv city in Ukraine and Szarów village in Poland). All used agrochemicals showed partial protective effects against ozone injury on clover and tobacco. Conducted studies confirmed the effectiveness of modern fungicides belonging to strobilurin group as protectants of sensitive crops against ozone damage. The effectiveness of new growth regulators "Emistym C" and "Agrostymulin" was showed for the first time. Out of the studied agrochemicals, fungicide "Strobi" and natural growth regulator "Emistym C" demonstrated the best protective effects. These agrochemicals present promise for further studies of their possible utilization for enhancement of ozone tolerance of sensitive crops.

Trend of environmental radiation protection and its current related studies

International Nuclear Information System (INIS)

Yoshida, Satoshi

2011-01-01

Reviewed are the international trend of environmental radiation protection (ERP), Japanese studies of radiation effects on environmental livings from aspects of ecosystem to molecular level, and the future view. ERP is particularly closed up toward promotion after its first involvement in the general global conference, UN Conference on Environment and Development (1992). International Commission of Radiological Protection (ICRP) has conducted such actions for the environment as establishing protection essentials for non-human species (2003), organizing Committee 5 (2005), and defining Reference Animals and Plants (2008) where Derived Consideration Reference Levels of 0.1-100 mGy/d are proposed, together with cooperative actions by United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR), International Atomic Energy Agency (IAEA), The Organization for Economic Co-operation and Development (OECD)/Nuclear Energy Agency (NEA) and European projects. Japanese NIRS is now enrolled in the project of Environmental Modeling for Radiation Safety-II (IAEA). Major Japanese studies of radiation effects on environmental livings have utilized killifish (medaka: Oryzias latipes), springtail, earthworm, nematode, cultured plant cell (cedar), poplar, etc. Studies of the radiation effect on microcosm consisting of 3 livings have led to establishing a model for mathematical analysis and of 8 livings, have defined 50% affect dose of 5600 Gy gamma-ray. Irradiation of gamma-ray at 1 Gy/d for 5-10 days to the soil has been shown to result in alteration of the composition of natural earth bacterial population by denaturant gradient gel electrophoresis, which being a promising tool for evaluating the alteration of soil composition and function. At molecular levels, transcriptome analysis of various cells from yeast to man, is performed after irradiation of gamma-ray, neutron, heavy particles and others to reveal radiation-induced gene expression; and Hi-CEP (high

Online Gambling Advertising Regulations in Spain. A Study on the Protection of Minors.

Science.gov (United States)

Buil, Pilar; Solé Moratilla, Maria José; García Ruiz, Pablo

2015-09-15

This article examines the online gambling advertising regulations in Spain currently in effect to assess the actual protection of underage youth. In recent years, online gambling among youth has increased. Through advertising, online gambling companies incite and encourage an involvement that can be harmful for vulnerable audiences. Some studies have demonstrated that advertising influences youths' assessment of gambling by increasing its appeal. We demonstrate that the shortcomings of the legal framework in force results in effective vulnerability of minors. We claim that society should seek to implement a regulatory framework to protect children from the risk of developing an addiction.

Employment protection legislation in Croatia

Directory of Open Access Journals (Sweden)

Marina Kunovac

2014-06-01

Full Text Available According to business climate and competitiveness indicators published by international organisations, Croatia is a country with a rigid labour market and a high level of the legal protection of employees. Given that an Act on Amendments to the Labour Act (OG 73/13 entered into force in Croatia in June 2013, this paper examines changes in employment protection legislation in Croatia and Central and Eastern European (CEE countries, as well as in Croatia's main trading partners during the period between 2008 and 2013. A cross-country comparison shows a strong downward trend in legal employment protection in most CEE countries during the observed period, primarily as concerns individual dismissal in the cases of regular employment contracts, while in the case of temporary employment the protection strengthened slightly. On the other hand, despite the adoption of amendments to the Labour Act (LA, Croatian labour legislation governing employment protection for regular employment contracts remains relatively inflexible compared to that in other countries.

Strengthening the radiation protection culture: a priority of EDF radiation protection policy

International Nuclear Information System (INIS)

Garcier, Y.

2006-01-01

Full text of publication follows: In order to improve the management of radiation protection at EDF nuclear power plants, the Human Factors Group of the Research and Development Division of EDF has performed some studies on the appropriation process of the radiation protection requirements. These studies have notably shown that an efficient application of the radiation protection requirements lies on a comprehension by all workers of the meaning of these requirements. Furthermore, they should not be applied under the constraint or because of the fear of a sanction, but the workers need to perceive and understand the benefits in terms of protection associated with the radiation protection requirements. The strengthening of the radiation protection culture is therefore a key element of the radiation protection policy developed by EDF. This culture lies on an awareness of the health risks potentially associated with low levels of ionising radiations, as well as on the knowledge of tools, techniques and good practices developed to control the level of exposures and improve the radiation protection. Various type of actions have been undertaken to reinforce among the relevant players (exposed and non-exposed workers, contractors, all levels of management,... ) an awareness of radiation protection in order to integrate it in their day to day work: elaboration of a 'radiation protection system of reference' explaining how the radiation protection regulatory requirements are applied at EDF, publication of a 'radiation protection handbook' available for all workers (including contractors), training sessions, creation of networks of specialists from the various nuclear power plants on specific radiation protection issues, organisation of feed-back experience forum, etc. Beyond these specific actions, i t is also important to ensure a support and an assistance on the field by dedicated specialists. In this perspective, the health physicists have to play a key role in order to

Correlates of Sun Protection and Sunburn in Children of Melanoma Survivors.

Science.gov (United States)

Tripp, Mary K; Peterson, Susan K; Prokhorov, Alexander V; Shete, Sanjay S; Lee, Jeffrey E; Gershenwald, Jeffrey E; Gritz, Ellen R

2016-09-01

Sunburns during childhood increase melanoma risk. Children of melanoma survivors are at higher risk, but little is known about their sunburn and sun protection. One study showed that almost half of melanoma survivors' children experienced sunburn in the past year. This study evaluated sunburn and sun protection in melanoma survivors' children, and relevant survivor characteristics from Social Cognitive Theory and the Health Belief Model. Melanoma survivors (N=340) were recruited from a comprehensive cancer center. Survivors completed a baseline questionnaire administered by telephone to report on the behavior of their children (N=340) as part of an RCT of a sun protection intervention. Data were collected in 2008 and analyzed in 2015. In the prior 6 months, 28% of children experienced sunburn. "Always" or "frequent" sun protection varied by behavior: sunscreen, 69%; lip balm, 15%; wide-brimmed hats, 9%; sleeved shirts, 28%; pants, 48%; sunglasses, 10%; shade, 33%; and limiting time outdoors, 45%. Survivors' sunburn and sun protection were positively associated with these outcomes in children. Correlates of sunburn also included older child age and higher risk perceptions. Correlates of sun protection behaviors included younger child age; stronger intentions, higher self-efficacy, and more positive outcome expectations about sun protection; and greater number of melanomas in survivors. Melanoma survivors may have a heightened awareness of the importance of their children's sun protection, but their children are not routinely protected. Correlates of children's sunburn and sun protection suggest subgroups of survivors to target with interventions to improve sun protection. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Study for magnets and electronics protection in the LHC Betatron-cleaning insertion

International Nuclear Information System (INIS)

Magistris, Matteo; Ferrari, Alfredo; Santana, Mario; Tsoulou, Katerina; Vlachoudis, Vasilis

2006-01-01

The collimation system of the future LHC at CERN is a challenging project, since the transverse energy intensities of the LHC beams are three orders of magnitude greater than at other current facilities. The two cleaning insertions (IR3 and IR7) housing the collimators will be among the most radioactive areas of LHC. The 1.5 km long IR7 insertion was fully implemented with the Monte Carlo cascade code FLUKA. Extensive simulations were performed to estimate the radiation level along the tunnel, as well as the energy deposition in the most critical elements. In particular, this paper discusses the latest results of the FLUKA studies, including the design of passive absorbers (to protect warm magnets) and a comparison of W and Cu as material for the active absorber jaws (to protect cold magnets). Any electronic device operating in strong radiation fields such as those expected for the LHC tunnel will undergo degradation. A shielding study was done to reduce radiation damage to the electronics

Latent fingerprints on different type of screen protective films

Directory of Open Access Journals (Sweden)

Yuttana Sudjaroen

2016-07-01

Full Text Available The purpose of this research was to study the quality of latent fingerprint on different types of screen protective films including screen protector, matte screen protector, anti-fingerprint clear screen protector and anti-fingerprint matte screen protector by using black powder method in developing latent fingerprints. The fingerprints were performed by 10 volunteers whose fingers (right index, right thumb, left index and left thumb were stubbing at different types of screen protective films and subsequently latent fingerprints were developed by brushing with black powder. Automated Fingerprint Identification System (AFIS counted the numbers of minutiae points from 320 latent fingerprints. Anti-fingerprint matte screen protective film produced the best quality of latent fingerprint with an average minutiae point 72.65, followed by matte screen protective film, clear screen protective film and anti-fingerprint clear screen protective film with an average minutiae point of 155.2, 135.0 and 72.65 respectively. The quality of latent fingerprints developed between a clear and a matte surface of screen protective films showed a significant difference (sig>0.05, whereas the coat and the non-coat with anti-fingerprint chemical revealed a non-significant difference (sig<0.05 in their number of minutiae points.

The USA National Longitudinal Lesbian Family Study (NLLFS): homophobia, psychological adjustment, and protective factors

NARCIS (Netherlands)

Bos, H.M.W.; Gartrell, N.K.; Peyser, H.; van Balen, F.

2008-01-01

The study assessed the influence of protective factors on the psychological adjustment of children who had experienced homophobia and whose mothers were participants in a longitudinal study of planned lesbian families. Data were collected as part of the National Longitudinal Lesbian Family Study by

Graphene-protected copper and silver plasmonics

DEFF Research Database (Denmark)

Kravets, V. G.; Jalil, R.; Kim, Y. J.

2014-01-01

suitable for plasmonic applications. To this end, there has been a continuous search for alternative plasmonic materials that are also compatible with complementary metal oxide semiconductor technology. Here we show that copper and silver protected by graphene are viable candidates. Copper films covered...... with one to a few graphene layers show excellent plasmonic characteristics. They can be used to fabricate plasmonic devices and survive for at least a year, even in wet and corroding conditions. As a proof of concept, we use the graphene-protected copper to demonstrate dielectric loaded plasmonic...

Microbial contamination of contact lenses after scaling and root planing using ultrasonic scalers with and without protective eyewear: A clinical and microbiological study

Directory of Open Access Journals (Sweden)

Rooh Afzha

2016-01-01

Full Text Available Background: Ultrasonic scaler is a preferential treatment modality among the clinicians. However, the aerosol/splatter generated is a concern for patients and practitioners. Therefore, the purpose of this study was to evaluate contamination of contact lenses of the dentist after scaling and root planing using ultrasonic scalers with and without protective eyewear. Materials and Methods: Thirty patients were randomly selected for scaling and root planing and divided into 2 groups of 15 each. Group A - dentist wearing contact lenses and protective eyewear. Group B - dentist wearing only contact lenses. After scaling and root planing using ultrasonic scalers, the lenses were subjected to culture and 16S rRNA (16S ribosomal RNA gene sequencing. Results: In Group A – 15 out of thirty samples were contaminated, in Group B – all the thirty samples were contaminated. Most of the samples showed Gram-positive bacteria and 5 samples were contaminated with fungi. 16S rRNA gene sequencing of forty contaminated samples showed that 31 were contaminated with Streptococcus mutans and 9 with Staphylococcus aureus. Conclusion: Keeping in mind the limitation of the study for the absence of negative control, we would like to conclude that dental practitioners should better avoid contact lenses in a dental setup because of the risk of contamination of the contact lenses from the various dental procedures which can produce aerosol/splatter and if worn, it is recommended to wear protective eyewear.

Interventions to promote the wearing of hearing protection.

Science.gov (United States)

El Dib, R P; Verbeek, J; Atallah, A N; Andriolo, R B; Soares, B G O

2006-04-19

, or no reminder. No significant differences in the mean use of hearing protection were found. A second randomised controlled trial evaluated the effect of a four year school based hearing loss prevention programme among pupils working at their parents farms (N=753) in a cluster randomised controlled trial. The intervention group was twice as likely to wear some kind of hearing protection as the control group that received only minimal intervention. All results are based on self reported use of hearing protection. Limited evidence does not show whether tailored interventions are more or less effective than general interventions in workers, 80% of whom already use hearing protection. Long lasting school based interventions may increase the use of hearing protection substantially. These results are based on single studies only. Better interventions to enhance the use of hearing protection need to be developed and evaluated in order to increase the prevention of noise induced hearing loss among workers.

Fishing inside or outside? A case studies analysis of potential spillover effect from marine protected areas, using food web models

Science.gov (United States)

Colléter, Mathieu; Gascuel, Didier; Albouy, Camille; Francour, Patrice; Tito de Morais, Luis; Valls, Audrey; Le Loc'h, François

2014-11-01

Marine protected areas (MPAs) are implemented worldwide as an efficient tool to preserve biodiversity and protect ecosystems. We used food web models (Ecopath and EcoTroph) to assess the ability of MPAs to reduce fishing impacts on targeted resources and to provide biomass exports for adjacent fisheries. Three coastal MPAs: Bonifacio and Port-Cros (Mediterranean Sea), and Bamboung (Senegalese coast), were used as case studies. Pre-existing related Ecopath models were homogenized and ecosystem characteristics were compared based on network indices and trophic spectra analyses. Using the EcoTroph model, we simulated different fishing mortality scenarios and assessed fishing impacts on the three ecosystems. Lastly, the potential biomass that could be exported from each MPA was estimated. Despite structural and functional trophic differences, the three MPAs showed similar patterns of resistance to simulated fishing mortalities, with the Bonifacio case study exhibiting the highest potential catches and a slightly inferior resistance to fishing. We also show that the potential exports from our small size MPAs are limited and thus may only benefit local fishing activities. Based on simulations, their potential exports were estimated to be at the same order of magnitude as the amount of catch that could have been obtained inside the reserve. In Port Cros, the ban of fishing inside MPA could actually allow for improved catch yields outside the MPA due to biomass exports. This was not the case for the Bonifacio site, as its potential exports were too low to offset catch losses. This insight suggests the need for MPA networks and/or sufficiently large MPAs to effectively protect juveniles and adults and provide important exports. Finally, we discuss the effects of MPAs on fisheries that were not considered in food web models, and conclude by suggesting possible improvements in the analysis of MPA efficiency.

The financial protection effect of Ghana National Health Insurance Scheme: evidence from a study in two rural districts

Directory of Open Access Journals (Sweden)

Wang Hong

2011-01-01

Full Text Available Abstract Background One of the key functions of health insurance is to provide financial protection against high costs of health care, yet evidence of such protection from developing countries has been inconsistent. The current study uses the case of Ghana to contribute to the evidence pool about insurance's financial protection effects. It evaluates the impact of the country's National Health Insurance Scheme on households' out-of-pocket spending and catastrophic health expenditure. Methods We use data from a household survey conducted in two rural districts, Nkoranza and Offinso, in 2007, two years after the initiation of the Ghana National Health Insurance Scheme. To address the skewness of health expenditure data, the absolute amount of out-of-pocket spending is estimated using a two-part model. We also conduct a probit estimate of the likelihood of catastrophic health expenditures, defined at different thresholds relative to household income and non-food consumption expenditure. The analysis controls for chronic and self-assessed health conditions, which typically drive adverse selection in insurance. Results At the time of the survey, insurance coverage was 35 percent. Although the benefit package of insurance is generous, insured people still incurred out-of-pocket payment for care from informal sources and for uncovered drugs and tests at health facilities. Nevertheless, they paid significantly less than the uninsured. Insurance has been shown to have a protective effect against the financial burden of health care, reducing significantly the likelihood of incurring catastrophic payment. The effect is particularly remarkable among the poorest quintile of the sample. Conclusions Findings from this study confirm the positive financial protection effect of health insurance in Ghana. The effect is stronger among the poor group than among general population. The results are encouraging for many low income countries who are considering a

American ginseng tea protects cellular DNA within 2 h from consumption: results of a pilot study in healthy human volunteers.

Science.gov (United States)

Szeto, Yim Tong; Sin, Yuk Shan Pauline; Pak, Sok Cheon; Kalle, Wouter

2015-01-01

The acute genoprotective effect of Panax quinquefolius (American ginseng) has been investigated. The experiment was carried out to explore the DNA protective effect after a single dose of American ginseng tea bag infusion. Fourteen subjects (6 males and 8 females) were recruited in this study. Seven of them (3 males and 4 females) were asked to drink a cup of freshly prepared American ginseng infusions. Water was taken by the remaining subjects as the control group. Blood samples of both groups were taken before and 2 h post-ingestion. The blood samples were challenged with ultraviolet B irradiation followed by using comet assay. Completed slides were stained with Giemsa stain and DNA damage was assessed. Results showed a significant decrease in comet score after American ginseng supplementation and no change in the control group. The current study demonstrated a cup of American ginseng infusion could protect cellular DNA from oxidative stress at least within 2 h.

Iris Template Protection Based on Local Ranking

Directory of Open Access Journals (Sweden)

Dongdong Zhao

2018-01-01

Full Text Available Biometrics have been widely studied in recent years, and they are increasingly employed in real-world applications. Meanwhile, a number of potential threats to the privacy of biometric data arise. Iris template protection demands that the privacy of iris data should be protected when performing iris recognition. According to the international standard ISO/IEC 24745, iris template protection should satisfy the irreversibility, revocability, and unlinkability. However, existing works about iris template protection demonstrate that it is difficult to satisfy the three privacy requirements simultaneously while supporting effective iris recognition. In this paper, we propose an iris template protection method based on local ranking. Specifically, the iris data are first XORed (Exclusive OR operation with an application-specific string; next, we divide the results into blocks and then partition the blocks into groups. The blocks in each group are ranked according to their decimal values, and original blocks are transformed to their rank values for storage. We also extend the basic method to support the shifting strategy and masking strategy, which are two important strategies for iris recognition. We demonstrate that the proposed method satisfies the irreversibility, revocability, and unlinkability. Experimental results on typical iris datasets (i.e., CASIA-IrisV3-Interval, CASIA-IrisV4-Lamp, UBIRIS-V1-S1, and MMU-V1 show that the proposed method could maintain the recognition performance while protecting the privacy of iris data.

Radiation protection optimization of workers

International Nuclear Information System (INIS)

Lochard, J.

1994-11-01

This report presents the contribution of CEPN (study center on protection evaluation in nuclear area) to the Days of the French Radiation Protection Society (SFRP) on optimization of workers radiation protection in electronuclear, industrial and medical areas

Constructing vulnerabilty and protective measures indices for the enhanced critical infrastructure protection program.

Energy Technology Data Exchange (ETDEWEB)

Fisher, R. E.; Buehring, W. A.; Whitfield, R. G.; Bassett, G. W.; Dickinson, D. C.; Haffenden, R. A.; Klett, M. S.; Lawlor, M. A.; Decision and Information Sciences; LANL

2009-10-14

NIPP framework incorporates consequence, threat, and vulnerability components and addresses all hazards. The analysis of the vulnerability data needs to be reproducible, support risk analysis, and go beyond protection. It also needs to address important security/vulnerability topics, such as physical security, cyber security, systems analysis, and dependencies and interdependencies. This report provides an overview of the approach being developed to estimate vulnerability and provide vulnerability comparisons for sectors and subsectors. the information will be used to assist DHS in analyzing existing protective measures and vulnerability at facilities, to identify potential ways to reduce vulnerabilities, and to assist in preparing sector risk estimates. The owner/operator receives an analysis of the data collected for a specific asset, showing a comparison between the facility's protection posture/vulnerability index and those of DHS sector/subsector sites visited. This comparison gives the owner/operator an indication of the asset's security strengths and weaknesses that may be contributing factors to its vulnerability and protection posture. The information provided to the owner/operator shows how the asset compares to other similar assets within the asset's sector or subsector. A 'dashboard' display is used to illustrate the results in a convenient format. The dashboard allows the owner/operator to analyze the implementation of additional protective measures and to illustrate how such actions would impact the asset's Protective Measures Index (PMI) or Vulnerability Index (VI).

Plant dynamics studies towards design of plant protection system for PFBR

Energy Technology Data Exchange (ETDEWEB)

Natesan, K., E-mail: natesan@igcar.gov.in [Nuclear and Safety Engineering Group, Indira Gandhi Centre for Atomic Research, Kalpakkam 603 102 (India); Kasinathan, N.; Velusamy, K.; Selvaraj, P.; Chellapandi, P. [Nuclear and Safety Engineering Group, Indira Gandhi Centre for Atomic Research, Kalpakkam 603 102 (India)

2012-09-15

Highlights: Black-Right-Pointing-Pointer Analysis of various design basis events in a fast breeder reactor towards design of plant protection system. Black-Right-Pointing-Pointer Plant dynamic modeling of a sodium cooled fast breeder reactor. Black-Right-Pointing-Pointer Selection of optimum set of plant parameters for considering best plant availability. - Abstract: Prototype fast breeder reactor (PFBR) is a 500 MWe (1250 MWt) liquid sodium cooled pool type reactor currently under construction in India. For a safe and efficient operation of the plant, it is necessary that the reactor is protected from all the transients that may occur in the plant. In order to accomplish this, adequate number of SCRAM parameters is required in the plant protection system with reliable instrumentation. For identifying the SCRAM parameters, the neutronic and thermal hydraulic responses of the plant for various possible events need to be established. Towards this, a one dimensional plant dynamics code DYANA-P has been developed with thermal hydraulic models for reactor core, hot and cold pools, intermediate heat exchangers, pipelines, steam generator, primary sodium circuits and secondary sodium circuits. The code also incorporates neutron kinetics and reactivity feedback models. By a comprehensive plant dynamics study an optimum list of SCRAM parameters and the maximum permissible response time for various instruments used for deriving them have been arrived at.

DNA-protective effects of sumach (Rhus coriaria L.), a common spice: Results of human and animal studies

Energy Technology Data Exchange (ETDEWEB)

Chakraborty, Asima; Ferk, Franziska; Simic, Tatjana [Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna (Austria); Brantner, Adelheid [Institute of Pharmacognosy, University of Graz, Universitaetsplatz 4/I, A-8010 Graz (Austria); Dusinska, Maria [Center for Ecological Economics, Norwegian Institute for Air Research, Instituttveien 18, NO-2027 Kjeller (Norway); Kundi, Michael [Institute of Environmental Health, Center for Public Health, Medical Unviversity of Vienna (Austria); Hoelzl, Christine; Nersesyan, Armen [Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna (Austria); Knasmueller, Siegfried [Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna (Austria)], E-mail: siegfried.knasmueller@meduniwien.ac.at

2009-02-10

Sumach (Rhus coriaria L.) is widely used as a spice. The aim of this study was the investigation of its DNA-protective effects in humans and animals. Prevention of the formation of strand breaks and oxidized DNA bases as well as the protection against H{sub 2}O{sub 2}- and ({+-})-anti-benzo[a]pyrene-7,8-dihydro-diol-9,10-epoxide (BPDE)-induced DNA-damage were monitored in human lymphocytes in a placebo controlled trial (N = 8/group) with ethanolic extract of sumach (3.0 g/day, 3 days) in single cell gel electrophoresis assays. Furthermore, DNA-protective effects of sumach were monitored in different inner organs of rats under identical conditions. No alteration of DNA-migration was detectable in human lymphocytes under standard conditions, but a decrease of the tail-lengths due to formation of oxidized purines and pyrimidines (52% and 36%) was found with lesion-specific enzymes. Also damage caused by H{sub 2}O{sub 2} and BPDE was significantly reduced by 30% and 69%, respectively. The later effect may be due to induction of glutathione S-transferase (GST). After the intervention, the overall GST (CDNB) activity in plasma was increased by 40%, GST-{alpha} by 52% and GST-{pi} by 26% (ELISA). The antioxidant effects of extract are probably due to scavenging which was observed in in vitro experiments, which also indicated that gallic acid is the active principle of sumach. The animal experiments showed that sumach also causes protection in inner organs. Supplementation of the drinking water (0.02 g/kg per animal) decreased the formation of oxidized DNA bases in colon, liver, lung and lymphocytes; also after {gamma}-irradiation pronounced effects were seen.

An outlook to radiation protection development

International Nuclear Information System (INIS)

Martincic, R.; Strohal, P.

1996-01-01

Radiation protection and safety have developed over many decades as the effects of ionizing radiation have been better and better understood. Some events in the last decade had essential impact on radiation protection policy/philosophy and related safety standards. Among them are available data of some long term radio-epidemiological studies of populations exposed to radiation. Investigations of the survivors of the atomic bombing of Hiroshima and Nagasaki illustrated that exposure to radiation has also a potential for the delayed induction of malignancies. They also showed that irradiation of pregnant women may result with certain mental damage in foetus. Several big radiation accidents which appeared in the last decade also had an impact on developments in radiation protection philosophy and practices. A well known Chernobyl accident showed that limited knowledge was available at the time of the accident on transfer of radionuclides in a specific environment, radioecological effects and pathways of highly radioactive atmospheric precipitation generated during the accident on various components of the environment. New scientific data indicated also that in some parts of human environment there are measurable effects of chronic exposure resulting from natural radiation. UNSCEAR is periodically publishing the most valuable set of data as compilation, and disseminates information on the health effects of radiation and on levels of radiation exposure due to different sources. These data are also the best guidelines for the necessary improvements and updating of radiation protection practices and philosophies. The latest ICRP-60 publication and recently issued International Basic Safety Standards for Protection Against Ionizing Radiation and for the Safety of Radiation Sources are reflecting many of the above mentioned findings. On the other hand the use of radiation sources is increasing day by day, and many new facilities applying radiation in radiotherapy

Preventive radiation protection in Hamburg

International Nuclear Information System (INIS)

Boikat, U.; Lauer, R.; Plath, S.; Sachde, Z.G.

2001-01-01

Monitoring of environmental radioactivity as well as complex investigations for precautionary radiation protection are carried out in Hamburg by two radiation monitoring labs. The spectrum of their tasks is specified by the media to be investigated. The tasks are originating from the Federal Precautionary Radiation Protection Act and from local needs. Mostly since a lot of years all interesting materials are analysed for their radioactivity content, as a safe and precautionary radiation protection demands. Until today samples show the influence of global nuclear weapon fallout of the period until 1964. Partly they show the radioactivity of Caesium originating from the Chernobyl accident. Since ten years the radioactivity contents in the material investigated are decreasing. Mostly the activity reached levels as at the end of 1985. The basic food stuff investigated in Hamburg can be considered as to be uncontaminated by radioactivity. With the introduction of the Federal Precautionary Radiation Protection Act, a series of new investigation programs and investigation methods were developed. This allows a better preparedness for extraordinary situations of increased radioactivity in the environment as 12 years ago. Thus a precise assessment of situations of increased radioactivity levels can be given together with coordinated and solid information to the public concerning provisions and actions. (orig.) [de

Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study.

Science.gov (United States)

Ladha, Karim; Vidal Melo, Marcos F; McLean, Duncan J; Wanderer, Jonathan P; Grabitz, Stephanie D; Kurth, Tobias; Eikermann, Matthias

2015-07-14

To evaluate the effects of intraoperative protective ventilation on major postoperative respiratory complications and to define safe intraoperative mechanical ventilator settings that do not translate into an increased risk of postoperative respiratory complications. Hospital based registry study. Academic tertiary care hospital and two affiliated community hospitals in Massachusetts, United States. 69,265 consecutively enrolled patients over the age of 18 who underwent a non-cardiac surgical procedure between January 2007 and August 2014 and required general anesthesia with endotracheal intubation. Protective ventilation, defined as a median positive end expiratory pressure (PEEP) of 5 cmH2O or more, a median tidal volume of less than 10 mL/kg of predicted body weight, and a median plateau pressure of less than 30 cmH2O. Composite outcome of major respiratory complications, including pulmonary edema, respiratory failure, pneumonia, and re-intubation. Of the 69,265 enrolled patients 34,800 (50.2%) received protective ventilation and 34,465 (49.8%) received non-protective ventilation intraoperatively. Protective ventilation was associated with a decreased risk of postoperative respiratory complications in multivariable regression (adjusted odds ratio 0.90, 95% confidence interval 0.82 to 0.98, P=0.013). The results were similar in the propensity score matched cohort (odds ratio 0.89, 95% confidence interval 0.83 to 0.97, P=0.004). A PEEP of 5 cmH2O and median plateau pressures of 16 cmH2O or less were associated with the lowest risk of postoperative respiratory complications. Intraoperative protective ventilation was associated with a decreased risk of postoperative respiratory complications. A PEEP of 5 cmH2O and a plateau pressure of 16 cmH2O or less were identified as protective mechanical ventilator settings. These findings suggest that protective thresholds differ for intraoperative ventilation in patients with normal lungs compared with those used for patients

Healthy eating habits protect against temptations.

Science.gov (United States)

Lin, Pei-Ying; Wood, Wendy; Monterosso, John

2016-08-01

Can healthy food-choice habits protect people against temptations of consuming large portion sizes and unhealthy foods? In two studies, we show that the answer is yes, good habits serve this protective role, at least in contexts in which people are not deliberating and thus fall back on habitual responses. In the first study, participants trained with unhealthy habits to approach eating chocolate, but not those trained with healthy habits, succumbed to temptation and ate more chocolates when their self-control resources were depleted. Study 2 extended and clarified these findings by demonstrating the role of environmental cues in eliciting healthy habits when self-control resources are depleted. Participants who had been trained to choose carrots habitually to a pictorial stimulus (i.e., habit cue) subsequently resisted choosing M&Ms as long as the cue was present. This effect of habit cues on healthy food choices suggests the usefulness of manipulating such cues as a means of meeting self-regulatory goals such as portion control. Copyright © 2015 Elsevier Ltd. All rights reserved.

Evaluation of radiation protection in nuclear medicine diagnostic procedures

International Nuclear Information System (INIS)

Mohammed, Ezzeldien Mohammed Nour

2013-05-01

This study conducted to evaluate the radiation protection in nuclear medicine diagnostic procedures in four nuclear medicine departments in Sudan. The evaluated procedures followed in these departments were in accordance with the standards, International Recommendations and code of practice for radiation protection in nuclear medicine. The evolution included the optimum design for diagnostic nuclear medicine departments, dealing with radioactive sources, quality assurance and quality control, training and responsibilities for radiation worker taking into account economic factors in Sudan. Evaluation of radiation protection procedures in diagnostic investigations was carried out by taken direct measurements of dose rate and the contamination level in some areas where radiation sources, radiation workers and public are involved. Designated questionnaires covered thirteen areas of radiation protection based on inspection check list for nuclear medicine prepared by the International Atomic Energy Agency (IAEA) and American Association of Physicist in Medicine (AAPM) were used in the evaluation. This questionnaire has been Filled by Radiation Protection Officer (RPO), nuclear medicine technologist, nuclear medicine specialist in the nuclear medicine departments. Four hospitals, two governmental hospital and two private hospitals, have been assisted, the assessment shows that although the diagnostic nuclear medicine department in Sudan are not applying a fully safety and radiation protection procedures, but the level of radiation dose and the contamination level were found within acceptable limits. The private hospital D scored the higher level of protection (85.25%) while the governmental hospital C scored the lower level of protection (59.02%). Finally, this study stated some recommendations that if implemented could improve the level of radiation protection in nuclear medicine department. One of the most important recommendations is that a proper radiation protection

Permissions and Prohibitions in Data Protection Jurisdiction

NARCIS (Netherlands)

Taylor, M.S.C.

Under public international law, a State has a right to exercise jurisdiction and is expected to show restraint when applying extraterritorial jurisdiction. The EU’s Data Protection Directive is far-reaching and has notable effects beyond its territory. The General Data Protection Regulation could

Radiological protection worker: occupational medical aspects

International Nuclear Information System (INIS)

Mora Ramirez, Erick

2008-01-01

International Organizations involved with radiation protection are presented in the first part. Also some documents related to the radiation that have been published by these organizations. Among the analyzed contents are the radiation and their patients, how to avoid the damage of radiation, pregnancy and exposure to medical radiation, effects of radiation, recommendations for the protection and safety standards. Occupational exposure is defined as the exposure received and understood by a worker during a period of work. In addition, it shows the types of occupational exposure, the protection that workers must have with the radiation, regulations, laws and the regulatory authority that protects the medical personnel in the uses of radiology [es

Thermal comfort sustained by cold protective clothing in Arctic open-pit mining-a thermal manikin and questionnaire study.

Science.gov (United States)

Jussila, Kirsi; Rissanen, Sirkka; Aminoff, Anna; Wahlström, Jens; Vaktskjold, Arild; Talykova, Ljudmila; Remes, Jouko; Mänttäri, Satu; Rintamäki, Hannu

2017-12-07

Workers in the Arctic open-pit mines are exposed to harsh weather conditions. Employers are required to provide protective clothing for workers. This can be the outer layer, but sometimes also inner or middle layers are provided. This study aimed to determine how Arctic open-pit miners protect themselves against cold and the sufficiency, and the selection criteria of the garments. Workers' cold experiences and the clothing in four Arctic open-pit mines in Finland, Sweden, Norway and Russia were evaluated by a questionnaire (n=1,323). Basic thermal insulation (I cl ) of the reported clothing was estimated (ISO 9920). The I cl of clothing from the mines were also measured by thermal manikin (standing/walking) in 0.3 and 4.0 m/s wind. The questionnaire showed that the I cl of the selected clothing was on average 1.2 and 1.5 clo in mild (-5 to +5°C) and dry cold (-20 to -10°C) conditions, respectively. The I cl of the clothing measured by thermal manikin was 1.9-2.3 clo. The results show that the Arctic open-pit miners' selected their clothing based on occupational (time outdoors), environmental (temperature, wind, moisture) and individual factors (cold sensitivity, general health). However, the selected clothing was not sufficient to prevent cooling completely at ambient temperatures below -10°C.

Understanding and mapping local conflicts related to protected areas in small islands: a case study of the Azores archipelago

Directory of Open Access Journals (Sweden)

Chiara Bragagnolo

2016-05-01

Full Text Available Establishing Protected Areas (PAs is considered one of the most appropriate ways to conserve nature and cultural landscapes. However, conservation constraints can generate social conflicts, especially at a local level. In small islands (SIs, local conflicts may escalate due to an increase in competition for limited space and resources. Pico island in the Azores Archipelago (Portugal, part of the Outermost European region, was considered a good case to study conservation-development conflicts due to the amount of designated protected land (> 35% of its surface and the approval of a new Azorean PA network in 2007. This paper presents a new approach to understanding and mapping local conflicts within PAs in SIs by integrating qualitative data and spatially explicit information. This research takes stock of the benefits, needs and constraints related to Pico Natural Park as perceived by local stakeholders through face-to-face semi-structured interviews; it subsequently identifies and transposes the conflicts distilled from stakeholder discourse into spatially representative visual maps via GIS. Research outcomes show that PAs are perceived mainly as constraints to local development, showing inconsistency between local expectations and regional conservation policy. This highlights the importance of including public participation processes prior to any implementation of conservation strategies. The proposed method provides a springboard towards effective conflict management for PAs on Pico island, showing a relatively low-cost and straightforward approach to minimising future local conflicts which could be adapted to other similar Outermost European regions and SIs.

Delivery of GM-CSF to Protect against Influenza Pneumonia.

Directory of Open Access Journals (Sweden)

Renuka Subramaniam

Full Text Available Since adaptive immunity is thought to be central to immunity against influenza A virus (IAV pneumonias, preventive strategies have focused primarily on vaccines. However, vaccine efficacy has been variable, in part because of antigenic shift and drift in circulating influenza viruses. Recent studies have highlighted the importance of innate immunity in protecting against influenza.Granulocyte-macrophage colony stimulating factor (GM-CSF contributes to maturation of mononuclear phagocytes, enhancing their capacity for phagocytosis and cytokine production.Overexpression of granulocyte macrophage-colony stimulating factor (GM-CSF in the lung of transgenic mice provides remarkable protection against IAV, which depends on alveolar macrophages (AM. In this study, we report that pulmonary delivery of GM-CSF to wild type young and aged mice abrogated mortality from IAV.We also demonstrate that protection is species specific and human GM-CSF do not protect the mice nor stimulates mouse immunity. We also show that IAV-induced lung injury is the culprit for side-effects of GM-CSF in treating mice after IAV infection, and introduce a novel strategy to deliver the GM-CSF to and retain it in the alveolar space even after IAV infection.

Delivery of GM-CSF to Protect against Influenza Pneumonia

Science.gov (United States)

Subramaniam, Renuka; Hillberry, Zachary; Chen, Han; Feng, Yan; Fletcher, Kalyn; Neuenschwander, Pierre; Shams, Homayoun

2015-01-01

Background Since adaptive immunity is thought to be central to immunity against influenza A virus (IAV) pneumonias, preventive strategies have focused primarily on vaccines. However, vaccine efficacy has been variable, in part because of antigenic shift and drift in circulating influenza viruses. Recent studies have highlighted the importance of innate immunity in protecting against influenza. Methods Granulocyte-macrophage colony stimulating factor (GM-CSF) contributes to maturation of mononuclear phagocytes, enhancing their capacity for phagocytosis and cytokine production. Results Overexpression of granulocyte macrophage-colony stimulating factor (GM-CSF) in the lung of transgenic mice provides remarkable protection against IAV, which depends on alveolar macrophages (AM). In this study, we report that pulmonary delivery of GM-CSF to wild type young and aged mice abrogated mortality from IAV. Conclusion We also demonstrate that protection is species specific and human GM-CSF do not protect the mice nor stimulates mouse immunity. We also show that IAV-induced lung injury is the culprit for side-effects of GM-CSF in treating mice after IAV infection, and introduce a novel strategy to deliver the GM-CSF to and retain it in the alveolar space even after IAV infection. PMID:25923215

Skin protection in the food industry.

Science.gov (United States)

Bauer, A; Kelterer, D; Bartsch, R; Stadeler, M; Elsner, P

2007-01-01

In food occupations, like in many other skin risk occupations, the regular use of personal protection equipment, i.e. of skin protection ointments and protective gloves, is recommended as well as regular skin care for the prevention of occupational hand dermatitis. We investigated the uptake and maintenance of different prevention strategies (instructions for skin protection and skin care, prevocational skin hardening with UV light) in food occupations and their efficacy in the primary prevention of vocationally caused hand dermatitis. We could show that the acceptance and regular use of skin protection and care measures could be significantly increased by theoretical and practical instructions in food industry trainees. The highest acceptance was seen with skin protection ointment (100%) and skin care (90%). Protective gloves (43.3%) were used to a lesser extent. The hand dermatitis point prevalence in the groups after 6 months was 13.3% (skin protection), 19.4% (UV hardening) and 29.1% (controls). These clinical trends were supported by statistically significant differences in the basal TEWL values. Adequate skin protection and regular skin care seem to be promising for the prevention of occupationally caused hand dermatitis. The experimental approach using UV hardening prevocationally did not fulfil the expectations.

The use of suction blisters to measure sunscreen protection against UVR-induced DNA damage.

Science.gov (United States)

Josse, Gwendal; Douki, Thierry; Le Digabel, Jimmy; Gravier, Eleonore; Questel, Emmanuel

2018-02-01

The formation of DNA photoproducts caused by solar UVR exposure needs to be investigated in-vivo and in particular in order to assess sunscreens' level of protection against solar genotoxicity. The study's purposes were: i) to evaluate if the roof of suction blisters is an appropriate sampling method for measuring photoproducts, and ii) to measure in-vivo sunscreen protection against cyclobutane pyrimidine dimers. Skin areas on the interior forearms of eight healthy volunteers were exposed in-vivo to 2 MED of simulated solar radiation (SSR) and to 15 MED on a sunscreen protected area. After irradiation, six suction blisters were induced and the blister roofs were collected. Analysis of SSR-induced CPDs was performed by two independent methods: a chromatography coupled to mass spectroscopy (HPLC-MS/MS) approach and a 3D-imaging of CPD immunostaining by multiphoton microscopy on floating epidermal sheets. HPLC-MS/MS analyses showed that SSR-unexposed skin presented no CPD dimers, whereas 2 MED SSR-exposed skin showed a significant number of TT-CPD. The sunscreen covered skin exposed to 15 MED appeared highly protected from DNA damage, as the amount of CPD-dimers remained below the detection limit. The multiphoton-immunostaining analysis consistently showed that no CPD staining was observed on the non-SSR-exposed skin. A significant increase of CPD staining intensity and number of CPD-positive cells were observed on the 2 MED SSR-exposed skin. Sunscreen protected skin presented a very low staining intensity and the number of CPD-positive cells remained very close to non-SSR-exposed skin. This study showed that suction blister samples are very appropriate for measuring CPD dimers in-vivo, and that sunscreens provide high protection against UVR-induced DNA damage. Copyright © 2017 Elsevier B.V. All rights reserved.

Implantation of inspection and radiation protection plan

International Nuclear Information System (INIS)

Cunha, J.L.R. da

1988-01-01

Methods, means and procedures adopted by Petrobras engineering service to survey safety radiation protection of the companies that carry out radiographic services of PETROBRAS are showed. The systematic used in certification of personel, procedures, audits and field survey concerning radiation protection, are described. (C.M.) [pt

Rhodiola rosea L extract shows protective activity against ...

African Journals Online (AJOL)

disease in 3xTg-AD mice. Methods: The cognitive function of 3xTg-AD mice was assessed using Morris water maze test. ... (DOAJ), African Journal Online, Bioline International, Open-J-Gate and Pharmacy Abstracts ..... potentially be developed as an alternative ... Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla. FM.

Rhodiola rosea L extract shows protective activity against ...

African Journals Online (AJOL)

Conclusion: The findings suggest that RRLE treatment may be a useful strategy for treating memory impairment induced by several neurodegenerative diseases. Keywords: Rhodiola rosea L., Alzheimer's disease, Neurodegenerative diseases, Memory impairment, NeuN-positive cells, Amyloid beta deposits ...

Caulis Lonicerae Japonicae extract shows protective effect on ...

African Journals Online (AJOL)

increases dramatically with life expectancy. Accordingly, the risk ..... menopause will disturb the balance between formation and ... turnover markers above were dose-dependently reversed by ... No conflict of interest associated with this work.

Sun-exposure knowledge and protection behavior in a North Chinese population: a questionnaire-based study.

Science.gov (United States)

Cheng, Shaowei; Lian, Shi; Hao, Yongjing; Kang, Nan; Li, Shujuan; Nie, Yanjun; Zhang, Fan

2010-08-01

Sun exposure can cause a range of skin disorders. Skin damage can be prevented by following certain sun-protection measures. However, the majority of reported studies regarding sun-exposure knowledge and behavior have involved Caucasian populations. A self-administered multiple-choice questionnaire was administered. The questionnaire consisted of 13 questions aimed at evaluating people's knowledge, awareness, and protection behavior regarding sun exposure, and their knowledge of sunscreens and sunscreen use. A total of 623 volunteers were enrolled, including 238 men (38.2%) and 385 women (61.8%). The percentages of correct answers regarding sun-exposure knowledge and awareness ranged from 50% to 80%. Overall, 58.8% used sunscreen as a sun-protection measure in daily life, followed by use of protective clothes (49.3%), sun umbrella (45.4%), sunglasses (45.3%), and hat (42.2%). Fifty-two percent thought that suntan was harmful or not attractive. The mean sun-protection factor (SPF) of the sunscreens used was 27.7 +/- 9.2 and the mean UVA protection grade (PA) was 2.3 +/- 0.6. Knowledge and awareness concerning the harmful effects of sun exposure are widespread among the Chinese population. Sunscreens with high SPF and PA are the most commonly used among Chinese people. Clear sex differences were observed. There is a significant difference in the attitude toward suntan between Chinese and Caucasian populations.

Protection from visible light by commonly used textiles is not predicted by ultraviolet protection.

Science.gov (United States)

Van den Keybus, Caroline; Laperre, Jan; Roelandts, Rik

2006-01-01

Interest is increasing in the prevention of acute and chronic actinic damage provided by clothing. This interest has focused mainly on protection against ultraviolet irradiation, but it has now also turned to protection against visible light. This change is mainly due to the action spectrum in the visible light range of some photodermatoses and the increasing interest in photodynamic therapy. The ultraviolet protection provided by commercially available textiles can be graded by determining an ultraviolet protection factor. Several methods have already been used to determine the ultraviolet protection factor. The fact that protection from visible light by textiles cannot be predicted by their ultraviolet protection makes the situation more complicated. This study attempts to determine whether or not the ultraviolet protection factor value of a particular textile is a good parameter for gauging its protection in the visible light range and concludes that a protection factor of textile materials against visible light needs to be developed. This development should go beyond the protection factor definition used in this article, which has some limitations, and should take into account the exact action spectrum for which the protection is needed.

DNA damage protection and 5-lipoxygenase inhibiting activity of ...

African Journals Online (AJOL)

DNA damage caused by free radical is associated with mutation-based health impairment. The protective effect on DNA damage mediated by hydroxyl radical and peroxynitrite radical, and the inhibiting activity on 5-lipoxygenase of areca inflorescence extracts were studied in vitro. The results show that the boiling water ...

Radiological protection study at the 'Hospital Edgardo Rebagliati Martins'/Peru

International Nuclear Information System (INIS)

Luna Q, R.

1996-01-01

Edgardo Rebagliati Martins Hospital of the Peruvian Institute of Social Security started its activities in 1957, as the largest metropolitan general hospital for the insured workers of the I.P.S.S. At present, it has 1350 hospital beds, attends 36,600 external consults per month, about 10,700 x-rays examinations, as well as 16,800 radiotherapy treatments monthly. 200 brachytherapies with Cesium or Radium are performed annually, besides many other (examinations) imaging exams that use ionizing radiation are carried out by our radiology staff with diagnosis or therapeutic purposes. This is the reason why the hospital directory sent some staff physicians abroad to learn all about radiation protection in a hospital setting, so that they will be able to organize a Radiation Protection Committee to advise and to set up rules and regulations to protect exposed personnel, as well as public in general, improving quality and, consequently, saving costs to the institution. The Constitution of the Radiation Protection Committee, its importance in a medical institution, is informed, and finally its experiences of the every day work and how to act in hospital accidents where ionizing radiation is involved, are transmitted. (author). 1 fig

Practical problems of groundwater model ages for groundwater protection studies

International Nuclear Information System (INIS)

Matthess, G.; Muennich, K.O.; Sonntag, C.

1976-01-01

Water authorities in the Federal Republic of Germany have established a system of protection zones for the protection of groundwater supplies from pollution. One zone (Zone II) is defined by an outer boundary from which the groundwater needs 50 days to flow to the well. 50 days is the period accepted for the elimination of pathogenic germs. However, within Zone II carbon-14 measurements of water may give model ages of several thousand years, which may lead to some confusion in the legal and practical aspects of this scheme. These model ages may result from uncertainties in the chemical model, or from mixing of waters of different ages, either within the aquifer or during extraction at the well. The paper discusses scientific aspects of the establishment of protection zones. Two processes affecting the model age determinations are examined in detail. First, the mechanism of diffusion transport downwards through porous, but impermeable, aquicludes is examined for stable trace substances and radioactive isotopes. Secondly, examples are given of model ages resulting from mixtures of new and old waters. It is recommended that such model ages should not be reported as 'ages' since they may be misinterpreted in groundwater protection applications. (author)

Aspects of radiological protection in nuclear installations

International Nuclear Information System (INIS)

Hunt, J.G.; Oliveira Filho, D.S.; Rabello, P.N.P.

1987-01-01

Due to the short term, long term and genetic effects of radiation, the work with radioactive materials requires special protection measures. The objective of radiological protection is to assure the occupational health of the workers by maintaining the dose levels as low as reasonably achievable. The radiological protection measures implanted in the NUCLEBRAS fuel element factory are described. The philosophy and practical measures taken are explained, and a comparison between radiation protection and industrial safety norms is made. The result of this work shows that the radiological safety of the element factory is assured. (author) [pt

Environmental radiation protection - a brief history

International Nuclear Information System (INIS)

Zapantis, A.P.

2003-01-01

The effects of ionising radiation on man has been studied intensely for decades, and the system of radiation protection for man has been continually refined in the light of those studies. That system assumes that if man is protected, non-human biota at the species level will also be adequately protected. However, an increasing recognition of the need to protect the environment, and international agreements signed in 1992, have resulted in that paradigm being questioned, with the onus shifting slowly towards demonstrating that the environment is protected. Further, radiation protection agencies and environmental protection agencies around the world have now started considering the issue of developing a system of radiation protection for the environment. The International Commission on Radiological Protection (ICRP) and the International Atomic Energy Agency (IAEA) are also active in this area. The purpose of this paper is to briefly outline some of the issues confronting environmental and radiation protection specialists, and to mention some of the initiatives being taken by the international community to resolve those issues

Recent study, but not retrieval, of knowledge protects against learning errors.

Science.gov (United States)

Mullet, Hillary G; Umanath, Sharda; Marsh, Elizabeth J

2014-11-01

Surprisingly, people incorporate errors into their knowledge bases even when they have the correct knowledge stored in memory (e.g., Fazio, Barber, Rajaram, Ornstein, & Marsh, 2013). We examined whether heightening the accessibility of correct knowledge would protect people from later reproducing misleading information that they encountered in fictional stories. In Experiment 1, participants studied a series of target general knowledge questions and their correct answers either a few minutes (high accessibility of knowledge) or 1 week (low accessibility of knowledge) before exposure to misleading story references. In Experiments 2a and 2b, participants instead retrieved the answers to the target general knowledge questions either a few minutes or 1 week before the rest of the experiment. Reading the relevant knowledge directly before the story-reading phase protected against reproduction of the misleading story answers on a later general knowledge test, but retrieving that same correct information did not. Retrieving stored knowledge from memory might actually enhance the encoding of relevant misinformation.

Experimental study of the protective effects of Zhongfei decoction on radiation-induced pneumonia in rats

International Nuclear Information System (INIS)

Wang Yuezhen; Ma Shenglin; Zhang Aiqin; Feng Jianguo; Fang Xianhua; Sun Xiaojiang; Bao Yejiang

2007-01-01

Objective: To investigate the protective effect and its possible mechanism of ZhongFei Decoction on radiation-induced pneumonia in rats. Methods: Single irradiation was given at two thorax of female Wistar rats with 30 Gy of 6 MV X irradiation. Sixty rats were randomly divided into the control group, radiation group, radiation plus DXM and ZhongFei Decoction plus radiation group. On days 14 and 28 after treatment, 5 rats of each group were sacrificed, and their lungs were harvested for measurement of the lung index, the difference of the histopathology change, the concentration of hydroxyproline (hyp), and expression of transforming growth factor-β1 in lungs were analyzed by HE stain, biochemical method and immunohistochemical method, respectively. Results: The pathological study showed marked lung injury in the radiation group while only slight hyperemia hemorrhage, exudation and thickness of alveolar walls in the lungs of ZhongFei Decoction plus radiation group, the concentration of hydroxyproline and expression of TGF-β1 in the radiation lungs increased compared with that in the control group and reduced in the ZhongFei Decoction plus radiation group compared with that in the radiation group. Conclusions: ZhongFei Decoction could have protective effects on the radiation-induced pneumonia and the mechanism of its may be related with down-regulating the expression of TGF-β1 in the irritated lung tissue. (authors)

Study on aging management of fire protection system in nuclear power plant

International Nuclear Information System (INIS)

Fang Huasong; Du Yu; Li Jianwen; Shi Haining; Tu Fengsheng

2010-01-01

Fire prevention, fire fighting and fire automatic alarms are three aspects which be included in fire protection system in nuclear power plants. The fire protection system can protect personnel, equipment etc in the fire, so their performance will have a direct influence on the safe operation in nuclear power plants. The disabled accidents caused by aging have happened continuously with the extension of time in the fire protection system, which is the major security risk during the running time in nuclear power plants. In view of the importance of fire protection system and the severity of aging problems, the aging are highly valued by the plant operators and related organizations. Though the feedback of operating experience in nuclear power plant, the impact of the fire-fighting equipment aging on system performance and reliability be assessed, the aging sensitive equipment be selected to carry out the aging analysis and to guide the management and maintenance to guarantee the healthy operation in life time of fire protection system in nuclear power plant. (authors)

Topologically protected states in one-dimensional systems

CERN Document Server

Fefferman, C L; Weinstein, M I

2017-01-01

The authors study a class of periodic Schrödinger operators, which in distinguished cases can be proved to have linear band-crossings or "Dirac points". They then show that the introduction of an "edge", via adiabatic modulation of these periodic potentials by a domain wall, results in the bifurcation of spatially localized "edge states". These bound states are associated with the topologically protected zero-energy mode of an asymptotic one-dimensional Dirac operator. The authors' model captures many aspects of the phenomenon of topologically protected edge states for two-dimensional bulk structures such as the honeycomb structure of graphene. The states the authors construct can be realized as highly robust TM-electromagnetic modes for a class of photonic waveguides with a phase-defect.

Study of the Effect of Sol pH and Nanoclay Incorporation on the Corrosion Protection Performance of a Silane Sol-Gel Coating

Directory of Open Access Journals (Sweden)

Najmeh Asadi

2014-06-01

Full Text Available This work is aimed to evaluate the role of nanoclay in the protective performance of an eco-friendly silane sol-gel layer applied on mild steel substrate in 0.1M sodium chloride solution. At the first step, the effect of pH of the silane solution, consisting of a mixture of γ-glycidoxypropiltrimethoxysilane and methyltriethoxysilane and tetraethoxysilane, on the coating performance was evaluated through electrochemical noise measurements. The values of characteristic charge as a parameter extracted from shot noise theory revealed that the sol pH determining the rate of hydrolysis can play an important role in the corrosion protection behavior of silane coatings. Then, the influence of clay nanoparticles on the corrosion protective performance of the hybrid silane film was studied through taking advantage of electrochemical techniques, including electrochemical impedance spectroscopy and polarization curves, as well as surface analysis methods. The obtained electrochemical data including the values of charge transfer resistance, coating resistance, low frequency impedance and corrosion current density showed that the silane sol gel film in the presence of clay nanoparticles can present an improved corrosion protection. The behavior was connected to an enhancement in the coating barrier properties. Moreover, FESEM and water contact angle confirmed the higher reticulation in case of the coating incorporating nanoclay.

Protective effect of Adeturone on E.coli survival

International Nuclear Information System (INIS)

Baldzhijska, M.; Minkova, M.; Pantev, T.

1980-01-01

Antiradiation potencies of AET, ATP, and the preparation Adeturone (AET salt of ATP) were studied in terms of E.coli survival following exposure to gamma-ray doses ranging from 1.29 K/kg to 20.64 K/kg AET was found to provide protection only in the case of the highest of three concentrations used, 625 micrograms per milliliter. ATP concentrations of 587 mcg/ml proved ineffective whether used solely or in a mixture with 262.5 mcg/ml of AET. These ineffective AET and ATP concentrations are equimolar with the amounts of AET and ATP contained in Adeturone. The latter showed a protective effect when applied at 625 mcg/ml, but failed to protect at a lower (312 mcg/ml) or at higher (1250 mcg/ml and 1500 mcg/ml) concentrations. Confirmative evidence was thus obtained that chemical binding of the two protectors raises the effectiveness of the combination

Protective effect of Adeturone on E. coli survival

Energy Technology Data Exchange (ETDEWEB)

Baldzhijska, M; Minkova, M; Pantev, T [Meditsinska Akademiya, Sofia (Bulgaria). Nauchen Inst. po Rentgenologiya i Radiobiologiya

1980-01-01

Antiradiation potencies of AET, ATP, and the preparation Adeturone (AET salt of ATP) were studied in terms of E.coli survival following exposure to gamma-ray doses ranging from 1.29 K/kg to 20.64 K/kg AET was found to provide protection only in the case of the highest of three concentrations used, 625 micrograms per milliliter. ATP concentrations of 587 mcg/ml proved ineffective whether used solely or in a mixture with 262.5 mcg/ml of AET. These ineffective AET and ATP concentrations are equimolar with the amounts of AET and ATP contained in Adeturone. The latter showed a protective effect when applied at 625 mcg/ml, but failed to protect at a lower (312 mcg/ml) or at higher (1250 mcg/ml and 1500 mcg/ml) concentrations. Confirmative evidence was thus obtained that chemical binding of the two protectors raises the effectiveness of the combination.

Protective equipment of radiological protection and the worker wear; Equipamento de protecao radiologica e o desgaste do trabalhador

Energy Technology Data Exchange (ETDEWEB)

Cassia, Flor Rita de; Huhn, Andrea, E-mail: flor@ifsc.edu.br [Instituto Federal de Educacao, Ciencia e Tecnologia de Santa Catarina (IFSC), Florianopolis, SC (Brazil); Lima, Gelbcke Francine, E-mail: fgelbcke@ccs.ufsc.br [Universidade Federal de Santa Catarina (PEN/UFSC), Florianopolis, SC (Brazil). Programa de Pos-Graduacao em Enfermagem

2013-11-01

This qualitative research with workers of seven hemodynamic service of Santa Catarina, Brazil aimed to analyze the use of radiological protection equipment (RPE), as well as wear to the health of workers who use these causes. The study was conducted between March 2010 and November 2010, totaling approximately 30 hours of observations. Results showed resistance to the use of RPE and also showed wear to workers' health, mainly due to the weight and discomfort they cause, as may weigh 7-9 pounds, depending on the model used. Evidenced also the absence of workers due herniated disc, back pain, and other musculo skeletal problems. These complaints, in addition to being related to the use of these protective gear also related with the time that workers remain standing for long periods on certain procedures, such as angioplasty. Given these results, the research recommended the use of these devices with materials, that are already being produced, making lighter aprons, thus avoiding fatigue and back pain and also provide greater comfort by reducing workers' resistance to its use and its adverse consequences.

Recovery Trends of Commercial Fish: The Case of an Underperforming Mediterranean Marine Protected Area.

Science.gov (United States)

Marra, Stefano; Coppa, Stefania; Camedda, Andrea; Mazzoldi, Carlotta; Wrachien, Francesco; Massaro, Giorgio; de Lucia, G Andrea

2016-01-01

Temporal trends in the recovery of exploited species in marine protected areas (MPAs) are useful for a proper assessment of the efficacy of protection measures. The effects of protection on the fish assemblages of the sublittoral rocky reefs in the "Penisola del Sinis-Isola di Mal di Ventre" MPA (W. Sardinia, Italy) were evaluated using a multi-year series of data. Four surveys, conducted 7, 10, 13 and 15 years after the area was designated as an MPA and carried out in the period spanning June and July, were used to estimate the abundance and biomass of commercial species. The surveys were carried out in zones with decreasing levels of fishing restrictions within the MPA (zones A, B, C) and in unprotected zones (OUT1 and OUT2), and underwater video visual census techniques were used. Protected zones only occasionally showed higher levels of abundance or biomass, and the trajectories of those metrics were not consistent across the years. In addition, the zone with the highest level of protection (zone A) never presented levels of abundance and biomass higher than those in zones B and C. This study shows that even 15 years after designation, protection has had no appreciable effect in the MPA studied. It is argued that this is emblematic of several shortcomings in the planning, regulation and enforcement frameworks of the MPA.

Advanced worker protection system

International Nuclear Information System (INIS)

Caldwell, B.; Duncan, P.; Myers, J.

1995-01-01

The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D ampersand D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D ampersand D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D ampersand D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project will result in the development of an Advanced Worker Protection System (AWPS). The AWPS will be built around a life support backpack that uses liquid air to provide cooling as well as breathing gas to the worker. The backpack will be combined with advanced protective garments, advanced liquid cooling garment, respirator, communications, and support equipment to provide improved worker protection, simplified system maintenance, and dramatically improve worker productivity through longer duration work cycles. Phase I of the project has resulted in a full scale prototype Advanced Worker Protection Ensemble (AWPE, everything the worker will wear), with sub-scale support equipment, suitable for integrated testing and preliminary evaluation. Phase II will culminate in a full scale, certified, pre-production AWPS and a site demonstration

Advanced worker protection system

Energy Technology Data Exchange (ETDEWEB)

Caldwell, B.; Duncan, P.; Myers, J.

1995-12-01

The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D&D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D&D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D&D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project will result in the development of an Advanced Worker Protection System (AWPS). The AWPS will be built around a life support backpack that uses liquid air to provide cooling as well as breathing gas to the worker. The backpack will be combined with advanced protective garments, advanced liquid cooling garment, respirator, communications, and support equipment to provide improved worker protection, simplified system maintenance, and dramatically improve worker productivity through longer duration work cycles. Phase I of the project has resulted in a full scale prototype Advanced Worker Protection Ensemble (AWPE, everything the worker will wear), with sub-scale support equipment, suitable for integrated testing and preliminary evaluation. Phase II will culminate in a full scale, certified, pre-production AWPS and a site demonstration.

Data-protection standards and confidentiality of HIV/AIDS status in the workplace - a South African case study.

Science.gov (United States)

Muskat-Gorska, Zuzanna

2008-11-01

The article contextualises an emerging new regime for information privacy in South Africa (i.e. the draft Protection of Personal Information Bill). Subsequently, it discusses the possibility of successful implementation of international data-protection standards in an environment where there is an urgent need to balance HIV/AIDS confidentiality rights with public health requirements. Also, the article presents a preliminary assessment of the possible impact of professionalisation (and outsourcing) of workplace HIV/AIDS management on workplace data-protection practices, and it identifies some spaces for social dialogue on HIV/AIDS-data treatment in South Africa. The study methods comprise an analysis of legal documents (concerning international data-protection standards and the development of law governing data protection and HIV/AIDS confidentiality in South Africa) and interviews conducted with workplace health managers and trade union representatives, in Johannesburg, in 2007.

Seasonal skin darkening in Chinese women: the Shanghaiese experience of daily sun protection.

Science.gov (United States)

Qiu, Huixia; Flament, Frederic; Long, Xiaohui; Wu, Jun; Xu, Mengzhi; Leger, Didier Saint; Meaudre, Helene; Senee, Jerome; Piot, Bertrand; Bazin, Roland

2013-01-01

The facial skin tone of two groups of Chinese women from Shanghai was compared using standard colorimetric space techniques during a 6-month interval between January and July 2011. During the study period, one group of women (n = 40) applied a potent sun-protective cosmetic product daily, while the other group (n = 40) did not use any sun protection. The results, based on images taken using a standardized digital camera coupled to a spectroradiometer, showed that sun protection largely mitigated changes in the components of skin tone, ie, lightness, melanization, and individual typology angle parameters. The skin darkening process appeared to be reduced or prevented in the sun-protected group when compared with the control group. The sun-protected women had participated in an earlier study in 2008, which confirmed that seasonal skin darkening occurs from winter through summer in Shanghaiese women. Comparing the data obtained in the winters of 2008 and 2011, we were able to identify better the impact of 3 years of aging on the components of skin tone. Comparing data between seasons on the same women with (2011 study) and without (2008 study) sun protection highlights the role of the test product in preventing skin darkening.

Studies in Bangladesh on ingestion and organ content of trace elements of importance in radiological protection

International Nuclear Information System (INIS)

Begum, M.; Miah, M.F.K.

1998-01-01

In order to characterize a Reference Asian Man for radiation protection a study on the ingestion and organ content of trace elements of importance in radiological protection has been taken up by the IAEA/RCA among the Asian Countries. Representative sampling sample collection, appropriate techniques for analysis, quality assurance etc. for the study of this project are important parameters for accurate measurements. Some elemental composition in drinking supply water (Tap water and ground water) in the Dhaka city in Bangladesh has been presented in this paper. (author)

Physical implementation of protected qubits

International Nuclear Information System (INIS)

Douçot, B; Ioffe, L B

2012-01-01

We review the general notion of topological protection of quantum states in spin models and its relation with the ideas of quantum error correction. We show that topological protection can be viewed as a Hamiltonian realization of error correction: for a quantum code for which the minimal number of errors that remain undetected is N, the corresponding Hamiltonian model of the effects of the environment noise appears only in the Nth order of the perturbation theory. We discuss the simplest model Hamiltonians that realize topological protection and their implementation in superconducting arrays. We focus on two dual realizations: in one the protected state is stored in the parity of the Cooper pair number, in the other, in the parity of the flux number. In both cases the superconducting arrays allow a number of fault-tolerant operations that should make the universal quantum computation possible. (key issues reviews)

Physical implementation of protected qubits

Science.gov (United States)

Douçot, B.; Ioffe, L. B.

2012-07-01

We review the general notion of topological protection of quantum states in spin models and its relation with the ideas of quantum error correction. We show that topological protection can be viewed as a Hamiltonian realization of error correction: for a quantum code for which the minimal number of errors that remain undetected is N, the corresponding Hamiltonian model of the effects of the environment noise appears only in the Nth order of the perturbation theory. We discuss the simplest model Hamiltonians that realize topological protection and their implementation in superconducting arrays. We focus on two dual realizations: in one the protected state is stored in the parity of the Cooper pair number, in the other, in the parity of the flux number. In both cases the superconducting arrays allow a number of fault-tolerant operations that should make the universal quantum computation possible.

Do Smartphone Power Users Protect Mobile Privacy Better than Nonpower Users? Exploring Power Usage as a Factor in Mobile Privacy Protection and Disclosure.

Science.gov (United States)

Kang, Hyunjin; Shin, Wonsun

2016-03-01

This study examines how consumers' competence at using smartphone technology (i.e., power usage) affects their privacy protection behaviors. A survey conducted with smartphone users shows that power usage influences privacy protection behavior not only directly but also indirectly through privacy concerns and trust placed in mobile service providers. A follow-up experiment indicates that the effects of power usage on smartphone users' information management can be a function of content personalization. Users, high on power usage, are less likely to share personal information on personalized mobile sites, but they become more revealing when they interact with nonpersonalized mobile sites.

Screening of new substances for radiation protection and technology development of efficacy improvement

Energy Technology Data Exchange (ETDEWEB)

Yoo, Byung Sun; Park, Sun Young; Jang, Eun Jung [Kyonggi University, Suwon (Korea, Republic of)

2005-03-15

To evaluate the radioprotective efficacy of candidate compounds, we examined the effects of selenium compounds, melatonin, and propolis on the colony forming efficiency (CFE) of gamma-irradiated CHO cells. - Protective effects of selenium compounds against radiation-induced cytotoxicity Sodium selenite showed protective effects at low concentrations against radiation-induced toxicity in CHO cells, whereas its effects were weak at higher concentrations. Selenomethionine also reduced the radiation-induced cytotoxicity. Both of these compounds showed highest protective effects at the concentration of 1 uM. - Protective effects of melatonin against radiation-induced cytotoxicity Melatonin showed the protective effects against radiation-induced cytotoxicity, and the protection was highest at 1 mM concentration. - Protective effects of selenium compounds against hydrogen peroxide-induced cytotoxicity Propolis showed dose-dependent inhibition of hydrogen peroxide-induced cytotoxicity. In particular, the highest inhibition was observed when propolis were treated at 0.3 and 1 ng/ml 24h prior to the hydrogen peroxide treatment. The protective effects of propolis was observed only when it was pretreated at least 8 hours before hydrogen peroxide treatment.

Screening of new substances for radiation protection and technology development of efficacy improvement

International Nuclear Information System (INIS)

Yoo, Byung Sun; Park, Sun Young; Jang, Eun Jung

2005-03-01

To evaluate the radioprotective efficacy of candidate compounds, we examined the effects of selenium compounds, melatonin, and propolis on the colony forming efficiency (CFE) of gamma-irradiated CHO cells. - Protective effects of selenium compounds against radiation-induced cytotoxicity Sodium selenite showed protective effects at low concentrations against radiation-induced toxicity in CHO cells, whereas its effects were weak at higher concentrations. Selenomethionine also reduced the radiation-induced cytotoxicity. Both of these compounds showed highest protective effects at the concentration of 1 uM. - Protective effects of melatonin against radiation-induced cytotoxicity Melatonin showed the protective effects against radiation-induced cytotoxicity, and the protection was highest at 1 mM concentration. - Protective effects of selenium compounds against hydrogen peroxide-induced cytotoxicity Propolis showed dose-dependent inhibition of hydrogen peroxide-induced cytotoxicity. In particular, the highest inhibition was observed when propolis were treated at 0.3 and 1 ng/ml 24h prior to the hydrogen peroxide treatment. The protective effects of propolis was observed only when it was pretreated at least 8 hours before hydrogen peroxide treatment

Unintended Sunburn: A Potential Target for Sun Protection Messages

Directory of Open Access Journals (Sweden)

Geraldine F. H. McLeod

2017-01-01

Full Text Available New Zealand (NZ has the highest melanoma incidence rate in the world. Primary prevention efforts focus on reducing sunburn incidence and increasing sun protective practices in the population. However, sunburn from excessive ultraviolet radiation (UVR remains common. To reduce sunburn incidence, it is important to examine those individuals who experience unintended sunburn. This study aims to use data from the NZ Triennial Sun Protection Survey to describe respondents who were not intending to tan but were sunburnt after outdoor UVR exposure. Information on sociodemographics, concurrent weather conditions, sun protection attitudes and knowledge, and outdoor behaviour was also collected. The results showed 13.5% of respondents’ experienced unintended sunburn during the survey weekend but had not attempted to obtain a tan that summer. Respondents who reported unintended sunburn were more likely than others to have been near water and in unshaded areas, used sunscreen, had higher SunSmart knowledge scores, had lower positive attitudes towards tanning, and were outdoors for a longer duration with less body coverage. As sunburn was unintended these respondents’ outdoor sun protective behaviours may be amenable to change. Future public health initiatives should focus on increasing sun protection (clothing and shade and reducing potential barriers to sun protection.

Unintended Sunburn: A Potential Target for Sun Protection Messages.

Science.gov (United States)

McLeod, Geraldine F H; Reeder, Anthony I; Gray, Andrew R; McGee, Rob

2017-01-01

New Zealand (NZ) has the highest melanoma incidence rate in the world. Primary prevention efforts focus on reducing sunburn incidence and increasing sun protective practices in the population. However, sunburn from excessive ultraviolet radiation (UVR) remains common. To reduce sunburn incidence, it is important to examine those individuals who experience unintended sunburn. This study aims to use data from the NZ Triennial Sun Protection Survey to describe respondents who were not intending to tan but were sunburnt after outdoor UVR exposure. Information on sociodemographics, concurrent weather conditions, sun protection attitudes and knowledge, and outdoor behaviour was also collected. The results showed 13.5% of respondents' experienced unintended sunburn during the survey weekend but had not attempted to obtain a tan that summer. Respondents who reported unintended sunburn were more likely than others to have been near water and in unshaded areas, used sunscreen, had higher SunSmart knowledge scores, had lower positive attitudes towards tanning, and were outdoors for a longer duration with less body coverage. As sunburn was unintended these respondents' outdoor sun protective behaviours may be amenable to change. Future public health initiatives should focus on increasing sun protection (clothing and shade) and reducing potential barriers to sun protection.

Evaluation of radiation protection and technical procedures in Wad Madani Heart Diseases and Surgery Center (WHDSC) (cardiac catheterization laboratory)

International Nuclear Information System (INIS)

Gesmallah, A. H. A.

2013-07-01

The purpose of this study is conducted in order to evaluate the application of radiation protection program, evaluate the design of cardiac catheterization laboratory, evaluate the effectiveness of radiation protection devices, evaluate personal monitoring, usage of G-Arm x-ray machine, to evaluate the responsibilities of radiation protection officer (RPO), to assess monitoring devices if available, and to assess patient patient dose in Wad Madani hear disease and surgery center in a period from march 2013 to june 2013. The most data in this study was obtained from the results of the team of quality assurance and control of radiation safety institute when they visited hospital on 14/2/2011 for inspection and calibration for issue of registration and licenses, except the data of patients dose which obtained from exposure parameters and dosimetric information's in the archive of G-arm x-ray fluoroscopic machine (which were 110 of cardiac catheterization diagnostic and therapeutic cases, 60 of adult patients and 50 of children. The patient data included age, weight, kv, mAs, DAP, air kerma, and fluoro time. The results of this study show that there is radiation protection program need correction and partially applied, the design of cardiac catheterization laboratory is accepted according to radiation safety institute team of quality control. Also the study shows that the radiation protection program devices are available and good condition and enough in number. The study shows that there are no personal monitoring devices and services and the radiological technologist are well trained to dial with the G-arm x-ray machine and to apply the radiation protection program effectively. Also the study states that the radiation protection officer could apply his responsibilities partially. Finally the study shows that there is a direct linear relationship between the patient's weight and (DAP, air kerma, kv, and mAs) concludes that there is excessive radiation dose in cardiac

Protective effect of grape seed extracts on human lymphocytes: a preliminary study.

Science.gov (United States)

Szeto, Yim Tong; Lee, Kit Yee; Kalle, Wouter; Pak, Sok Cheon

2013-03-01

Grape seed extracts (GSEs) possess a broad spectrum of antioxidative properties that protects various cells from free radicals and oxidative stress. In this study, the genoprotective effect of GSE on human lymphocytic DNA was studied using standard and lysed cell comet assays. Lymphocytes from 5 healthy subjects were pretreated with GSE in different concentrations. The standard and lysed cell comet assays were performed on treated, untreated, challenged, and unchallenged cells in parallel. Cells were then subjected to an oxidant challenge induced with 5-min exposures to hydrogen peroxide. In the standard comet assay, GSE significantly diminished hydrogen-peroxide-induced DNA damage in a dose-dependent manner. In the lysed cell assay, however, the antioxidant effect was diminished at a higher GSE concentration. Data indicate that the cell membrane might play a role in limiting cellular access to antioxidants, which directly affects the genoprotective or potential pro-oxidant effect of antioxidants on human DNA. Using both standard and lysed cell comet assays in parallel could be a useful way to elucidate the mechanism of protection or damage by antioxidants.

[Heel pressure ulcers. Comparative study between heel protective bandage and hydrocellular dressing with special form for the heel].

Science.gov (United States)

Torra i Bou, Joan-Enric; Rueda López, Justo; Camañes, Gemma; Herrero Narváez, Elias; Blanco Blanco, Joan; Martínez-Esparza, Elvira Hernández; Aneas Alcántara, Jesús; Verdú Soriano, José

2002-05-01

The heels, together with the sacra area, are one of the most frequent spots where pressure sores appear here in Spain. Any preventive measure against pressure sores on heels needs be oriented towards two main objectives: effective relief of pressure and its compatibility with localized care and skin inspection in order to detect lesions early on at least once a day. The authors planned a comparative, multi-centered, open, labeled and controlled study in which patients were assigned to two groups receiving these treatments: one received traditional preventive pressure sore treatment and a protective bandage on their heels while the other used a special Allevyn Heel hydrocellular dressing to protect their heels. The patients took part in this study over an eight week period. The response variable used to determine the effectiveness of the preventive measure in this study was the appearance of pressure sores. At the beginning, 130 patients were included in this study, 65 in each one of the treatment groups. In the bandage group, 50 patients finished this study while 61 in the dressing group finished this study. The appearance of pressure sores in the protective bandage group occurred in 44% of the patients, 22 out of 50, while in the dressing group, the occurrence rate was 3.3%, 2 out of 61 patients with a value of "ji" squared p pressure sore brought us a value of relative risk of 13.42 (IC 95%: 3.31-54.3) in the group wearing the protective bandage compared to the group wearing the dressing. The results of this study allow us to accept as valid the alternate hypothesis that there exist significant statistical differences between both treatment methods in favor of the Allevyn Heel dressing instead of the protective heel bandage. The use of this dressing, even though it is more expensive a priori than the protective bandage, in terms of unit cost for the product, has proven to be more effective in preventing pressure sores, and cheaper than the protective bandage if

Joint Optimization of Working and p-cycle Protection Capacity

DEFF Research Database (Denmark)

Stidsen, Thomas K.; Thomadsen, Tommy

2004-01-01

-cycles are significantly more efficient than rings and comparable to any meshed protection method. The results also show that substantial savings can be achieved when routing and protection is performed jointly as compared to when it is not. Based on the integer linear programming model, we discuss how protection costs...

Reliability analysis of protection system of advanced pressurized water reactor - APR 1400

International Nuclear Information System (INIS)

Varde, P. V.; Choi, J. G.; Lee, D. Y.; Han, J. B.

2003-04-01

Reliability analysis was carried out for the protection system of the Korean Advanced Pressurized Water Reactor - APR 1400. The main focus of this study was the reliability analysis of digital protection system, however, towards giving an integrated statement of complete protection reliability an attempt has been made to include the shutdown devices and other related aspects based on the information available to date. The sensitivity analysis has been carried out for the critical components / functions in the system. Other aspects like importance analysis and human error reliability for the critical human actions form part of this work. The framework provided by this study and the results obtained shows that this analysis has potential to be utilized as part of risk informed approach for future design / regulatory applications

Protective Effect of Theaflavin on Erythrocytes Subjected to In Vitro Oxidative Stress

Directory of Open Access Journals (Sweden)

Mahejabeen Fatima

2013-01-01

Full Text Available Antioxidant and free radical scavenging effect of black tea theaflavins has been shown in many epidemiological studies. In the present work we report the protective mechanism of tea theaflavins on biomarkers of oxidative stress, which are elevated during stress conditions. We hereby report the in vitro effect of theaflavins on erythrocyte malondialdehyde (MDA, intracellular reduced glutathione (GSH, and plasma membrane redox system (PMRS of rats. The effect of theaflavin on PMRS has also been validated through an in silico docking simulation study using Molegro Virtual Docker (MVD. We report that theaflavins show significant protection to erythrocyte against oxidative stress induced by tert-butyl hydroperoxide (t-BHP. The findings suggest a possible protective role of theaflavins as antioxidant.

[Child protection: Pediatricians' knowledge and practices in Brittany].

Science.gov (United States)

Ayou, C; Gauducheau, E; Arrieta, A; Roussey, M; Marichal, M; Vabres, N; Balençon, M

2018-04-01

On 5 March 2007, the law concerning the child protection system was reformed. Since then, child protection services have been responsible for the management of child abuse and neglect. Reporting and asking for child protection is now easier for every physician by submitting a "preoccupying information" form. A study conducted in 2014 in the general practitioners (GP) in the Ille-et-Vilaine department showed that they were quite unfamiliar with the child protection updates and that they needed special training. We wished to study the knowledge and practices of the pediatricians in Brittany and compare these results to the previous study. An anonymous postal investigation was conducted between May and July 2014. The questionnaire was referred to the previous study so the results would be comparable. A total of 134 pediatricians (including 99 women) of the 316 pediatricians of Brittany answered our questionnaire regarding their activity and their knowledge about child abuse and neglect. These results were analyzed and compared to the data of GPs in Ille-et-Vilaine. Only 4.4 % of the pediatricians obtained more than 80 % correct answers and 12 % of the pediatricians obtained fewer than 50 % correct answers. Among the pediatricians, 41 % of them had not reported a single time since 2007. The pediatricians who obtained better results (Pprotection is a neglected subject, including by pediatricians. To fight against professional denial and isolation, a substantial effort is still needed concerning caregivers' training as well as pediatric care organization. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Selective protection. Selektivschutz

Energy Technology Data Exchange (ETDEWEB)

1983-01-01

TC 2, ''Transmission and distribution of electrical energy'', held its meeting on selective protection on 16/17 March 1983 at Nuremberg. The main reason for the development of computerized protective systems is their ability to solve a wide range of tasks using only a few, high-integrated systems, i.e. on the software side instead of the hardware side. At the meeting, experts from industrial companies and public utilities reviewed the status and trends of protective systems engineering. Scientific studies and operating experience were presented. Separate abstracts were prepared for 2 papers in this conference proceedings volume.

Are gloves sufficiently protective when hairdressers are exposed to permanent hair dyes? An in vivo study.

Science.gov (United States)

Antelmi, Annarita; Young, Ewa; Svedman, Cecilia; Zimerson, Erik; Engfeldt, Malin; Foti, Caterina; Bruze, Magnus

2015-04-01

The use of permanent hair dyes exposes hairdressers to contact allergens such as p-phenylenediamine (PPD), and the preventive measures are insufficient. To perform an in vivo test to study the protective effect of gloves commonly used by hairdressers. Six gloves from Sweden, Italy and Germany were studied: two vinyl, one natural rubber latex, two nitrile, and one polyethylene. The hair dye used for the provocation was a dark shade permanent dye containing PPD. The dye was mixed with hydrogen peroxide, and 8 PPD-sensitized volunteers were tested with the gloves as a membrane between the hair dye and the skin in a cylindrical open chamber system. Three exposure times (15, 30 and 60 min) were used. Eczematous reactions were found when natural rubber latex, polyethylene and vinyl gloves were tested with the dye. The nitrile gloves gave good protection, even after 60 min of exposure to the hair dye. Many protective gloves used by hairdressers are unsuitable for protection against the risk of elicitation of allergic contact dermatitis caused by PPD. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Protection enhances community and habitat stability: evidence from a mediterranean marine protected area.

Science.gov (United States)

Fraschetti, Simonetta; Guarnieri, Giuseppe; Bevilacqua, Stanislao; Terlizzi, Antonio; Boero, Ferdinando

2013-01-01

Rare evidences support that Marine Protected Areas (MPAs) enhance the stability of marine habitats and assemblages. Based on nine years of observation (2001-2009) inside and outside a well managed MPA, we assessed the potential of conservation and management actions to modify patterns of spatial and/or temporal variability of Posidonia oceanica meadows, the lower midlittoral and the shallow infralittoral rock assemblages. Significant differences in both temporal variations and spatial patterns were observed between protected and unprotected locations. A lower temporal variability in the protected vs. unprotected assemblages was found in the shallow infralittoral, demonstrating that, at least at local scale, protection can enhance community stability. Macrobenthos with long-lived and relatively slow-growing invertebrates and structurally complex algal forms were homogeneously distributed in space and went through little fluctuations in time. In contrast, a mosaic of disturbed patches featured unprotected locations, with small-scale shifts from macroalgal stands to barrens, and harsh temporal variations between the two states. Opposite patterns of spatial and temporal variability were found for the midlittoral assemblages. Despite an overall clear pattern of seagrass regression through time, protected meadows showed a significantly higher shoot density than unprotected ones, suggesting a higher resistance to local human activities. Our results support the assumption that the exclusion/management of human activities within MPAs enhance the stability of the structural components of protected marine systems, reverting or arresting threat-induced trajectories of change.

Deploying Difference: Security Threat Narratives and State Displacement from Protected Areas

Directory of Open Access Journals (Sweden)

Elizabeth Lunstrum

2018-01-01

Full Text Available State actors are increasingly treating protected areas as sites of security threats and policing resident communities as though they are the cause of this insecurity. This is translating into community eviction from protected areas that is authorised by security concerns and logics and hence not merely conservation concerns. We ground this claim by drawing upon empirical work from two borderland conservation areas: Mozambique's Limpopo National Park (LNP and Guatemala's Maya Biosphere Reserve (MBR. In both cases, we show how these security-provoked evictions are authorised by the mobilisation of interlocking axes of difference that articulate notions of territorial trespass with that of a racialised enemy. Rather than a new problem or phenomena, we show how these axes are rooted in prior histories of state actors rendering racialised subjects dangerous, Cold War histories in both cases and a longer colonial history with the LNP. We also show how standing behind these evictions is the nation-state and its practices of protected area territorialisation. From here, we illustrate how the rationale behind displacement from protected areas matters, as evictions become more difficult to contest once they are authorised by security considerations. The cases, however, differ in one key respect. While displacement from the LNP is an instance of conservation-induced displacement (CID, although one re-worked by security considerations, eviction from the MBR is motivated more centrally by security concerns yet takes advantage of protected area legislation. The study hence offers insight into a growing literature on conservation-security encounters and into different articulations of conservation, security, and displacement.

A Study on Establishment of Unacceptable Radiological Consequence (URC) for Physical Protection against Sabotage

Energy Technology Data Exchange (ETDEWEB)

Jung, Myungtak; Koh, Moonsung; Lee, Youngwook; Jo, Kwang Ho [Korea Institute of Nuclear Nonproliferation and Control, Daejeon (Korea, Republic of)

2014-05-15

The international community has recommended that a graded approach should be applied to the establishment of the domestic regime for physical protection in accordance with fundamental principle H of the amended Convention on Physical Protection of Nuclear Material (CPPNM) and INFCIRC/225/rev.5. In Korea, Currently, the graded approach to unauthorized removal of nuclear material is divided into three categories (Category Ι, Category ΙΙ, Category ΙΙΙ) based on the IAEA INFCIRC/225/rev.5. Moreover, depending on the categorization of nuclear material, physical protection measures against unauthorized removal are also clearly categorized. But in the case of physical protection against sabotage, the graded approach to the physical protection measures is not applied since Unacceptable Radiological Consequence (URC) for identifying sabotage target and level is not determined. URC can be established based on either dose limit or design limit. The report by Sandia National Lab. in USA specifies that core damage is used for URC. Calculation of an exact dose is based on various assumptions and processes and subsequently increases uncertainty. Therefore, using design limit for decreasing uncertainty is more effective than using dose limit. In order to apply the graded approach to physical protection against sabotage, we have taken into Fundamental principle H : Physical protection requirements should be based on a graded approach, taking into account the current evaluation of the threat, the relative attractiveness, the nature of the material and potential consequences associated with the unauthorized removal of nuclear material and with the sabotage against nuclear material of nuclear facilities consideration legal and institutional standards on domestic and international radiological consequences and intended to provide a reference for the URC establishment by the State. The study on various standards led to the conclusion that each value has advantages and

Space Flight Orthostatic Intolerance Protection

Science.gov (United States)

Luty, Wei

2009-01-01

This paper summarizes investigations conducted on different orthostatic intolerance protection garments. This paper emphasizes on the engineering and operational aspects of the project. The current Shuttle pneumatic Anti-G Suit or AGS at 25 mmHg (0.5 psi) and customized medical mechanical compressive garments (20-30 mmHg) were tested on human subjects. The test process is presented. The preliminary results conclude that mechanical compressive garments can ameliorate orthostatic hypotension in hypovolemic subjects. A mechanical compressive garment is light, small and works without external pressure gas source; however the current garment design does not provide an adjustment to compensate for the loss of mass and size in the lower torso during long term space missions. It is also difficult to don. Compression garments that do not include an abdominal component are less effective countermeasures than garments which do. An early investigation conducted by the Human Adaptation and Countermeasures Division at Johnson Space Center (JSC) has shown there is no significant difference between the protection function of the AGS (at 77 mmHg or 1.5 psi) and the Russian anti-g suit, Kentavr (at 25 mmHg or 0.5 psi). Although both garments successfully countered hypovolemia-induced orthostatic intolerance, the Kentavr provided protection by using lower levels of compression pressure. This more recent study with a lower AGS pressure shows that pressures at 20-30 mmHg is acceptable but protection function is not as effective as higher pressure. In addition, a questionnaire survey with flight crewmembers who used both AGS and Kentavr during different missions was also performed.

The Protection of Animals in Thailand--An Insight into Animal Protection Legislation

Directory of Open Access Journals (Sweden)

Sulaiman Dorloh

2017-09-01

Full Text Available There are many critics of current Thai law concerning the welfare of animals. They argue that the PACPAWA,2014 is inadequate to protect the welfare of animals. The absence of clear guidelines in the legislation concerning animal welfare has resulted in animal welfare receiving inadequate protection. There are other limitations contributing to the inadequacy of existing laws in protecting animals in Thailand. The possible penalties are very low. For the offence of cruelty against an animal, the PACPAWA,2014 sets a maximum fine of TBH 2000. This is considered inadequate and ineffective in preventing cruelty to animals. The study utilises doctrinal legal research or library-based research approach to provide valuable insights in understanding the law and and ascertaining the principles of legal interpretation and analysis. The study also provides possible suggestions to enhance the protection of the welfare of animals in Thailand. The research suggests that education should play an important role in promoting kindness towards animals.

In Vitro Ruminal Degradability of Soybean Meal Protein Protected with Natural Tannin

Science.gov (United States)

Prasetiyono, B. W. H. E.; Subrata, A.; Tampoebolon, B. I. M.; Surono; Widiyanto

2018-02-01

The influence of tannin from tea waste and gambier as natural tannin sources on ruminal protein degradability was studied in this investigation. The soybean meal was used as protein source in this investigation. There were three treatments in this investigation mainly without protection (NT); protection with tea waste (Tt); and protection with gambier (Tg). The measured parameters consisted of in vitro dry matter digestibility (IVDMD), in vitro organic matter digestibility (IVOMD), and the ruminal fermentation characteristics. Results of this experiment showed that protection with tannin from tea waste as well as gambier increased (pRUP) in Tt and Tg group was higher than that in NT group (66.29 and 69.20 vs 51.10%). The ruminal protozoa population decreased (pRUP. The ruminal protozoa population and ammonia concentration, on the other hand, were decreased by tannin protection from those tannin natural sources. The natural tannin from gambier was the most effective protection agent for soybean meal protein.

Filtration of nanoparticles - Application to respiratory protecting devices

International Nuclear Information System (INIS)

Brochot, C.

2012-01-01

This study aims to determine how the respiratory protective devices (RPD), whose performances are qualified for particles above 100 nm, are effective for nanoparticles. Indeed, if the use of a collective filtration is inadequate, wearing a RPD is the last protection recommended. A literature review showed that no research concerned the effectiveness of half-masks for nanoparticles. The test bench ETNA has been sized and built to overcome these lacks. Two half masks were tested according to different configurations: constant flow rate and cyclic flow rate (average flow of 84 L /min), particle size (from 5 to 100 nm), positions of the mask (sealed, usual, or with calibrated leaks). The results show that, since the RPD contain high efficiency filter media (without charged fibers) for the most penetrating particle size (100 nm - 300 nm), the RPD is more efficient for nanoparticles. Furthermore, the results obtained in the presence of actual and calibrated leaks, highlighted the importance of face seal leakages in determining the performance of RPD. A model for calculating the protection factor was established based on the balance between the airflow through the filter and the leak. This model was validated using measurements obtained in the presence of calibrated leaks, and applied for the analysis of our results in usual position. (author)

Individual protections and ergonomics

International Nuclear Information System (INIS)

2000-01-01

The object of this conference was the protective clothing against radioactive contamination. The regulatory frame, the physiological constraints and the human factor are the different aspects studied through the conference with a constant objective, the optimization of radiation protection. (N.C.)

Protecting the skin during thyroidectomy

Directory of Open Access Journals (Sweden)

Renan Bezerra Lira

Full Text Available In this note we describe the standard technical maneuver used in our department to protect the skin during thyroidectomy in order to get the best aesthetic result. We use surgical gloves to protect the skin during these operations to reduce the negative impact of thermal trauma and mechanical retractors and energy delivery devices at the edges of the skin incised. This practice is effective, inexpensive, rapid, reproducible and showed no complication in our experience of over 2,500 thyroidectomies.

Safety study of fire protection for nuclear fuel cycle facility

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-08-15

Based on the investigation of fire protection standards for domestic and foreign nuclear facilities, the fire protection guideline for nuclear fuel cycle facility has been completed. In 2012, trial operation is started by private company using the guideline. In addition, the acquisition of fire evaluation data for a components (electric cable) targeted for spread of fire and the evaluation model of fire source were continued for the fire hazard analysis (FHA). (author)

Safety study of fire protection for nuclear fuel cycle facility

International Nuclear Information System (INIS)

2013-01-01

Based on the investigation of fire protection standards for domestic and foreign nuclear facilities, the fire protection guideline for nuclear fuel cycle facility has been completed. In 2012, trial operation is started by private company using the guideline. In addition, the acquisition of fire evaluation data for a components (electric cable) targeted for spread of fire and the evaluation model of fire source were continued for the fire hazard analysis (FHA). (author)

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study.

Science.gov (United States)

Geisbert, Thomas W; Lee, Amy C H; Robbins, Marjorie; Geisbert, Joan B; Honko, Anna N; Sood, Vandana; Johnson, Joshua C; de Jong, Susan; Tavakoli, Iran; Judge, Adam; Hensley, Lisa E; Maclachlan, Ian

2010-05-29

We previously showed that small interfering RNAs (siRNAs) targeting the Zaire Ebola virus (ZEBOV) RNA polymerase L protein formulated in stable nucleic acid-lipid particles (SNALPs) completely protected guineapigs when administered shortly after a lethal ZEBOV challenge. Although rodent models of ZEBOV infection are useful for screening prospective countermeasures, they are frequently not useful for prediction of efficacy in the more stringent non-human primate models. We therefore assessed the efficacy of modified non-immunostimulatory siRNAs in a uniformly lethal non-human primate model of ZEBOV haemorrhagic fever. A combination of modified siRNAs targeting the ZEBOV L polymerase (EK-1 mod), viral protein (VP) 24 (VP24-1160 mod), and VP35 (VP35-855 mod) were formulated in SNALPs. A group of macaques (n=3) was given these pooled anti-ZEBOV siRNAs (2 mg/kg per dose, bolus intravenous infusion) after 30 min, and on days 1, 3, and 5 after challenge with ZEBOV. A second group of macaques (n=4) was given the pooled anti-ZEBOV siRNAs after 30 min, and on days 1, 2, 3, 4, 5, and 6 after challenge with ZEBOV. Two (66%) of three rhesus monkeys given four postexposure treatments of the pooled anti-ZEBOV siRNAs were protected from lethal ZEBOV infection, whereas all macaques given seven postexposure treatments were protected. The treatment regimen in the second study was well tolerated with minor changes in liver enzymes that might have been related to viral infection. This complete postexposure protection against ZEBOV in non-human primates provides a model for the treatment of ZEBOV-induced haemorrhagic fever. These data show the potential of RNA interference as an effective postexposure treatment strategy for people infected with Ebola virus, and suggest that this strategy might also be useful for treatment of other emerging viral infections. Defense Threat Reduction Agency. Copyright 2010 Elsevier Ltd. All rights reserved.

The role of privacy protection in healthcare information systems adoption.

Science.gov (United States)

Hsu, Chien-Lung; Lee, Ming-Ren; Su, Chien-Hui

2013-10-01

Privacy protection is an important issue and challenge in healthcare information systems (HISs). Recently, some privacy-enhanced HISs are proposed. Users' privacy perception, intention, and attitude might affect the adoption of such systems. This paper aims to propose a privacy-enhanced HIS framework and investigate the role of privacy protection in HISs adoption. In the proposed framework, privacy protection, access control, and secure transmission modules are designed to enhance the privacy protection of a HIS. An experimental privacy-enhanced HIS is also implemented. Furthermore, we proposed a research model extending the unified theory of acceptance and use of technology by considering perceived security and information security literacy and then investigate user adoption of a privacy-enhanced HIS. The experimental results and analyses showed that user adoption of a privacy-enhanced HIS is directly affected by social influence, performance expectancy, facilitating conditions, and perceived security. Perceived security has a mediating effect between information security literacy and user adoption. This study proposes several implications for research and practice to improve designing, development, and promotion of a good healthcare information system with privacy protection.

Dimethylglycine provides salt and temperature stress protection to Bacillus subtilis.

Science.gov (United States)

Bashir, Abdallah; Hoffmann, Tamara; Smits, Sander H J; Bremer, Erhard

2014-05-01

Glycine betaine is a potent osmotic and thermal stress protectant of many microorganisms. Its synthesis from glycine results in the formation of the intermediates monomethylglycine (sarcosine) and dimethylglycine (DMG), and these compounds are also produced when it is catabolized. Bacillus subtilis does not produce sarcosine or DMG, and it cannot metabolize these compounds. Here we have studied the potential of sarcosine and DMG to protect B. subtilis against osmotic, heat, and cold stress. Sarcosine, a compatible solute that possesses considerable protein-stabilizing properties, did not serve as a stress protectant of B. subtilis. DMG, on the other hand, proved to be only moderately effective as an osmotic stress protectant, but it exhibited good heat stress-relieving and excellent cold stress-relieving properties. DMG is imported into B. subtilis cells primarily under osmotic and temperature stress conditions via OpuA, a member of the ABC family of transporters. Ligand-binding studies with the extracellular solute receptor (OpuAC) of the OpuA system showed that OpuAC possesses a moderate affinity for DMG, with a Kd value of approximate 172 μM; its Kd for glycine betaine is about 26 μM. Docking studies using the crystal structures of the OpuAC protein with the sulfur analog of DMG, dimethylsulfonioacetate, as a template suggest a model of how the DMG molecule can be stably accommodated within the aromatic cage of the OpuAC ligand-binding pocket. Collectively, our data show that the ability to acquire DMG from exogenous sources under stressful environmental conditions helps the B. subtilis cell to cope with growth-restricting osmotic and temperature challenges.

Can Social Protection Improve Sustainable Development Goals for Adolescent Health?

Science.gov (United States)

Cluver, Lucie D; Orkin, F Mark; Meinck, Franziska; Boyes, Mark E; Yakubovich, Alexa R; Sherr, Lorraine

2016-01-01

The first policy action outlined in the Sustainable Development Goals (SDGs) is the implementation of national social protection systems. This study assesses whether social protection provision can impact 17 indicators of five key health-related SDG goals amongst adolescents in South Africa. We conducted a longitudinal survey of adolescents (10-18 years) between 2009 and 2012. Census areas were randomly selected in two urban and two rural health districts in two South African provinces, including all homes with a resident adolescent. Household receipt of social protection in the form of 'cash' (economic provision) and 'care' (psychosocial support) social protection, and health-related indicators within five SDG goals were assessed. Gender-disaggregated analyses included multivariate logistic regression, testing for interactions between social protection and socio-demographic covariates, and marginal effects models. Social protection was associated with significant adolescent risk reductions in 12 of 17 gender-disaggregated SDG indicators, spanning SDG 2 (hunger); SDG 3 (AIDS, tuberculosis, mental health and substance abuse); SDG 4 (educational access); SDG 5 (sexual exploitation, sexual and reproductive health); and SDG 16 (violence perpetration). For six of 17 indicators, combined cash plus care showed enhanced risk reduction effects. Two interactions showed that effects of care varied by poverty level for boys' hunger and girls' school dropout. For tuberculosis, and for boys' sexual exploitation and girls' mental health and violence perpetration, no effects were found and more targeted or creative means will be needed to reach adolescents on these challenging burdens. National social protection systems are not a panacea, but findings suggest that they have multiple and synergistic positive associations with adolescent health outcomes. Such systems may help us rise to the challenges of health and sustainable development.

Can Social Protection Improve Sustainable Development Goals for Adolescent Health?

Directory of Open Access Journals (Sweden)

Lucie D Cluver

Full Text Available The first policy action outlined in the Sustainable Development Goals (SDGs is the implementation of national social protection systems. This study assesses whether social protection provision can impact 17 indicators of five key health-related SDG goals amongst adolescents in South Africa.We conducted a longitudinal survey of adolescents (10-18 years between 2009 and 2012. Census areas were randomly selected in two urban and two rural health districts in two South African provinces, including all homes with a resident adolescent. Household receipt of social protection in the form of 'cash' (economic provision and 'care' (psychosocial support social protection, and health-related indicators within five SDG goals were assessed. Gender-disaggregated analyses included multivariate logistic regression, testing for interactions between social protection and socio-demographic covariates, and marginal effects models.Social protection was associated with significant adolescent risk reductions in 12 of 17 gender-disaggregated SDG indicators, spanning SDG 2 (hunger; SDG 3 (AIDS, tuberculosis, mental health and substance abuse; SDG 4 (educational access; SDG 5 (sexual exploitation, sexual and reproductive health; and SDG 16 (violence perpetration. For six of 17 indicators, combined cash plus care showed enhanced risk reduction effects. Two interactions showed that effects of care varied by poverty level for boys' hunger and girls' school dropout. For tuberculosis, and for boys' sexual exploitation and girls' mental health and violence perpetration, no effects were found and more targeted or creative means will be needed to reach adolescents on these challenging burdens.National social protection systems are not a panacea, but findings suggest that they have multiple and synergistic positive associations with adolescent health outcomes. Such systems may help us rise to the challenges of health and sustainable development.

Reliability Analysis Study of Digital Reactor Protection System in Nuclear Power Plant

International Nuclear Information System (INIS)

Guo, Xiao Ming; Liu, Tao; Tong, Jie Juan; Zhao, Jun

2011-01-01

The Digital I and C systems are believed to improve a plants safety and reliability generally. The reliability analysis of digital I and C system has become one research hotspot. Traditional fault tree method is one of means to quantify the digital I and C system reliability. Review of advanced nuclear power plant AP1000 digital protection system evaluation makes clear both the fault tree application and analysis process to the digital system reliability. One typical digital protection system special for advanced reactor has been developed, which reliability evaluation is necessary for design demonstration. The typical digital protection system construction is introduced in the paper, and the process of FMEA and fault tree application to the digital protection system reliability evaluation are described. Reliability data and bypass logic modeling are two points giving special attention in the paper. Because the factors about time sequence and feedback not exist in reactor protection system obviously, the dynamic feature of digital system is not discussed

Older Adults' Perceptions of Nutrition as Protective Against Detrimental Effects of Environmental Pollution.

Science.gov (United States)

Dunn, Kristina; Gaetke, Lisa; Stephenson, Tammy; Brewer, Dawn

2017-08-01

The aging process makes older adults vulnerable to the detrimental health effects of environmental contaminants. Our study assessed older adults' perceptions regarding diet being protective against environmental contaminants, their levels of concern about exposure, and their interest in learning about protective food-related strategies. A needs assessment to collect such information has not been conducted among older adults. Health fair survey results showed that they perceived diet as beneficial against contaminants, were concerned about health implications of exposure, and were interested in learning how to protect health through diet-related strategies. Results suggest that a nutrition-focused curriculum addressing how dietary strategies can help protect against environmental contaminants is needed for Extension professionals.

Preventive Radiation Protection Act

International Nuclear Information System (INIS)

Roewer, H.

1988-01-01

The commentary is intended to contribute to protection of the population by a practice-oriented discussion and explanation of questions arising in connection with the Preventive Radiation Protection Act. Leaving aside discussions about abandonment of nuclear power, or criticism from any legal point of view, the commentary adopts the practical approach that accepts, and tries to help implementing, the act as it is. It is a guide for readers who are not experts in the law and gives a line of orientation by means of explanations and sometimes by citations from other acts (in footnotes). The commentary also presents the EURATOM Directive No. 3954/87 dated 22 December 1987, the EC Directive No. 3955/87 dated 22 December 1987, and the EC Directive No. 1983/88 dated 5 July 1988. A tabular survey shows the system of duties and competences defined by the Preventive Radiation Protection Act. (RST) [de

A study on the radiation and environmental safety -Development of radiation protection and measurement technology-

Energy Technology Data Exchange (ETDEWEB)

Jang, See Yung; Lee, Tae Yung; Lee, Hyung Sub; Kim, Jan Ryul; Kim, Chang Kyung; Kim, Bong Hwan; Yoon, Kyung Soo; Jung, Kyung Kee; Jung, Duk Yun; Lee, Bong Jae; Chul, Yoon Suk; Lee, Kee Chang; Yoon, Yu Chang; Jung, Rae Ik; Lee, Sang Yoon; Han, Yung Dae; Kim, Jong Soo, I; Kim, Jong Soo, II; Suh, Kyung Won [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Kim, Jong Kyung [Han Yang Univ., Seoul (Korea, Republic of)

1995-07-01

Reference X- and neutron radiation fields have been established and evaluated to support the national radiation protection programme under which performance evaluation test for domestic personal dosimetry will be implemented by the ministerial ordinance 1992-15, and to provide a basic technical support in radiation protection dosimetry. Personal dose evaluation algorithm has been developed with the KAERI reference radiation fields which comply well with those in the new ANSI N13.11(1993) to evaluate accurate personal dose equivalents. A personal internal dosimetry algorithm which can estimate the intakes of radionuclides from the results of whole body direct bioassay and the resulting internal doses has been also developed and evaluated to be equally excellent compared with those being used in foreign countries. A BOMAB phantom for precise WBC calibration has also designed, fabricated and test-evaluated. A principal method for estimating the cost for radiation protection which is important in performing a cost-benefit analysis for the radiation protection optimization study based on the ALARA principle has been preliminarily investigated and suggested. 49 figs, 67 tabs, 50 refs. (Author).

Understanding Social Conflicts Between Forestry and Nature Protection Sectors: Case Study Velebit Mountain

Directory of Open Access Journals (Sweden)

Konrad Kiš

2010-12-01

Full Text Available Background and Purpose: The last couple of decades brought significant changes in forest and nature protection policy worldwide. Rising environmental awareness, over-utilization of scarce natural resources and global climate change set high goals for the forest and nature protection policy makers. This paper is about a case study of relations among various stakeholders on Velebit Mountain, a coast-by mountain in Central Croatia. Velebit Mountain is both: a nature protection area and a forest exploitation site, which raises various conflicts between these two sectors and major stakeholders. Purpose of this research was to investigate the relations among various interest groups and coalition parties, their opinions, aspirations and interests and, especially, the way to resolve issues or manage conflicts. Material and Methods: This case-study research was conducted in form of interviews held with the representatives of each of the defined stakeholder groups within the target area, i.e. Velebit Mountain Nature Park. Interviews consisted of several groups of questions (introductory part, conflicts, conflict management and policy development, while stakeholder groups included "Croatian Forests ltd.", a state-owned company in charge of the management of state forests, Nature Park Velebit, National Park Paklenica, National Park "Northern Velebit", hunters' associations, private forest owners, fishermen associations, representatives of the local administration and mountaineers' associations. The questionnaire consisted of open-ended questions regarding various issues divided into these four groups. The data was analyzed by using the NVivo qualitative data analysis software. Theoretical framework used in this research was Walker and Daniels' Social Conflict Theory (1997, p.13 which describes types of conflicts, ways to address them and typical sources of occurring conflicts. Results and Conclusion: The results showed which the most salient conflict

76 FR 11482 - Request for Comments on Human Subjects Protections in Scientific Studies

Science.gov (United States)

2011-03-02

... President requested this study on November 24, 2010, following revelations that the U.S. Public Health... current U.S. and international standards for protecting the health and well-being of participants in... medical research; differences across global norms and standards; standards for ancillary care and post...

Experimental study of cathodic protection of concrete from a 30 year old bridge

NARCIS (Netherlands)

Polder, R.B.; Nerland, O.C.

1998-01-01

An experimental study of cathodic protection (CP) was carried out with a conductive primer anode applied to specimens from a concrete bridge. The bridge was demolished after 30 years of service due to severe delaminations and reinforcement corrosion. Four specimens of approximately 1 m2 each were

PROTECTIVE TREATMENTS FOR LAPPED PORCELAIN STONEWARE TILES AND EVALUATION OF THEIR CLEANABILITY

Directory of Open Access Journals (Sweden)

Elisa Rambaldi

2017-09-01

Full Text Available Since the arrival of lapped porcelain stoneware tiles on the market, several studies have been focused on the improvement of the technical characteristics of the surfaces of these products. Surface lapping induces aesthetical improvements, but can at the same time deteriorate the performance of porcelain stoneware tiles. To overcome this problem, it is possible to protect the lapped surface with commercial waterproofing materials. In this work, lapped commercial porcelain stoneware tiles with protective stain proofing agents (FILA PD15 and FILA 1239 Plus were evaluated. The stain resistance and chemical resistance results were correlated to the morphological surface characteristics of the products with and without protection. A systematic study of the surface porosity of the tiles was carried out. Results showed that unprotected surface pores tend to fill with dirt that is hardly removable by ordinary maintenance. If the pores are protected, the dirt from foot traffic is deposited only superficially and can be removed.

Protection against Amoebic Liver Abscess in Hamster by Intramuscular Immunization with an Autographa californica Baculovirus Driving the Expression of the Gal-Lectin LC3 Fragment

Directory of Open Access Journals (Sweden)

Dulce María Meneses-Ruiz

2015-01-01

Full Text Available In a previous study, we demonstrated that oral immunization using Autographa californica baculovirus driving the expression of the Gal-lectin LC3 fragment (AcNPV-LC3 of Entamoeba histolytica conferred protection against ALA development in hamsters. In this study, we determined the ability of AcNPV-LC3 to protect against ALA by the intramuscular route as well as the liver immune response associated with protection. Results showed that 55% of hamsters IM immunized with AcNPV-LC3 showed sterile protection against ALA, whereas other 20% showed reduction in the size and extent of abscesses, resulting in some protection in 75% of animals compared to the sham control group. Levels of protection showed a linear correlation with the development and intensity of specific antiamoeba cellular and humoral responses, evaluated in serum and spleen of hamsters, respectively. Evaluation of the Th1/Th2 cytokine patterns expressed in the liver of hamsters showed that sterile protection was associated with the production of high levels of IFNγ and IL-4. These results suggest that the baculovirus system is equally efficient by the intramuscular as well as the oral routes for ALA protection and that the Gal-lectin LC3 fragment is a highly protective antigen against hepatic amoebiasis through the local induction of IFNγ and IL-4.

Protection of stainless-steels against corrosion in sulphidizing environments by Ce oxide coatings: X-ray absorption and thermogravimetric studies

NARCIS (Netherlands)

Fransen, T.; Gellings, P.J.; Fuggle, J.C.; van der Laan, G.; Esteva, J.-M.; Karnatak, R.C.

1985-01-01

In this paper a study is reported concerning ceramic coatings containing cerium oxide, prepared by the sol-gel method, used to protect Incoloy 800H against sulphidation. When the coating is sintered in air at 850°C good protection is obtained. In an X-ray absorption spectroscopic study of the

Transformer Protection Using the Wavelet Transform

OpenAIRE

ÖZGÖNENEL, Okan; ÖNBİLGİN, Güven; KOCAMAN, Çağrı

2014-01-01

This paper introduces a novel approach for power transformer protection algorithm. Power system signals such as current and voltage have traditionally been analysed by the Fast Fourier Transform. This paper aims to prove that the Wavelet Transform is a reliable and computationally efficient tool for distinguishing between the inrush currents and fault currents. The simulated results presented clearly show that the proposed technique for power transformer protection facilitates the a...

Parameterization of a synchronous generator to represent a doubly fed induction generator with chopper protection for fault studies

DEFF Research Database (Denmark)

Martinez, Jorge; Kjær, Philip C.; Rodriguez, Pedro

2011-01-01

knowledge of the wind turbine short circuit current contribution is needed for component sizing and protection relay settings during faults within the wind power plant collector system or in the external networks. When studying fault currents and protection settings for wind power installations...

A Novel Adjustable Concept for Permeable Gas/Vapor Protective Clothing: Balancing Protection and Thermal Strain.

Science.gov (United States)

Bogerd, Cornelis Peter; Langenberg, Johannes Pieter; DenHartog, Emiel A

2018-02-13

Armed forces typically have personal protective clothing (PPC) in place to offer protection against chemical, biological, radiological and nuclear (CBRN) agents. The regular soldier is equipped with permeable CBRN-PPC. However, depending on the operational task, these PPCs pose too much thermal strain to the wearer, which results in a higher risk of uncompensable heat stress. This study investigates the possibilities of adjustable CBRN-PPC, consisting of different layers that can be worn separately or in combination with each other. This novel concept aims to achieve optimization between protection and thermal strain during operations. Two CBRN-PPC (protective) layers were obtained from two separate manufacturers: (i) a next-to-skin (NTS) and (ii) a low-burden battle dress uniform (protective BDU). In addition to these layers, a standard (non-CBRN protective) BDU (sBDU) was also made available. The effect of combining clothing layers on the levels of protection were investigated with a Man-In-Simulant Test. Finally, a mechanistic numerical model was employed to give insight into the thermal burden of the evaluated CBRN-PPC concepts. Combining layers results in substantially higher protection that is more than the sum of the individual layers. Reducing the airflow on the protective layer closest to the skin seems to play an important role in this, since combining the NTS with the sBDU also resulted in substantially higher protection. As expected, the thermal strain posed by the different clothing layer combinations decreases as the level of protection decreases. This study has shown that the concept of adjustable protection and thermal strain through multiple layers of CBRN-PPC works. Adjustable CBRN-PPC allows for optimization of the CBRN-PPC in relation to the threat level, thermal environment, and tasks at hand in an operational setting. © The Author(s) 2017. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

Sand erosion at the toe of a gabion-protected dune face

OpenAIRE

Chapman, A.

1992-01-01

The purpose of this research project was to study the manner in which erosion takes place the the toe of a dune slope protected by gabions, and to examine the response of the gabions to this erosion. A sand slope overlaid by model gabions was subjected to wave attack in a hydraulic flume, and periodic measurements of the bottom profile were taken. The results showed that the gabions performed well, and continued to provide protection to the slope even after a considerable amount of erosion an...

On population growth near protected areas.

Directory of Open Access Journals (Sweden)

Lucas N Joppa

Full Text Available Protected areas are the first, and often only, line of defense in efforts to conserve biodiversity. They might be detrimental or beneficial to rural communities depending on how they alter economic opportunities and access to natural resources. As such, protected areas may attract or repel human settlement. Disproportionate increases in population growth near protected area boundaries may threaten their ability to conserve biodiversity.Using decadal population datasets, we analyze population growth across 45 countries and 304 protected areas. We find no evidence for population growth near protected areas to be greater than growth of rural areas in the same country. Furthermore, we argue that what growth does occur near protected areas likely results from a general expansion of nearby population centers.Our results contradict those from a recent study by Wittemyer et al., who claim overwhelming evidence for increased human population growth near protected areas. To understand the disagreement, we re-analyzed the protected areas in Wittemyer et al.'s paper. Their results are simply artifacts of mixing two incompatible datasets. Protected areas may experience unusual population pressures near their edges; indeed, individual case studies provide examples. There is no evidence, however, of a general pattern of disproportionate population growth near protected areas.

submitter Radiation Protection Studies for CERN LINAC4/SPL Accelerator Complex

CERN Document Server

Mauro, Egidio; Silari, Marco

2009-01-01

CERN is presently designing a new chain of accelerators to replace the present Proton Synchrotron (PS) complex: a 160 MeV room-temperature H$^-$ linac (Linac4) to replace the present 50 MeV proton linac injector, a 3.5 GeV Superconducting Proton Linac (SPL) to replace the 1.4 GeV PS booster (PSB) and a 50 GeV synchrotron (named PS2) to replace the 26 GeV PS. Linac4 has been funded and the civil engineering work started in October 2008, whilst the SPL is in an advanced stage of design. Beyond injecting into the future 50 GeV PS, the ultimate goal of the SPL is to generate a 4 MW beam for the production of intense neutrino beams. The radiation protection design is driven by the latter requirement. This thesis summarizes the radiation protection studies conducted for Linac4. FLUKA Monte Carlo simulations, complemented by analytical estimates, were performed 1) to evaluate the propagation of neutrons through the waveguide, ventilation and cable ducts placed along the accelerator, 2) to estimate the radiological i...

Chemical protective clothing; a study into the ability of staff to perform lifesaving procedures

Science.gov (United States)

Coates, M.; Jundi, A.; James, M.

2000-01-01

Objective—To investigate the ability of medical and nursing staff to perform certain tasks while wearing a chemical protection suit with a respirator. Tasks chosen were those that would be required before decontamination. Methods—Ten experienced accident and emergency doctors (middle grade and consultants) and 10 nurses were asked to perform certain tasks that were judged to be life saving, relevant to triage, or necessary to confirm death, on an advanced life support manikin, while wearing a TST-Sweden chemical protection suit. The operators were objectively assessed by one of the authors for achieving each task, then asked to make a subjective assessment of the difficulty experienced. Results—Medical staff were asked to ventilate the manikin using a bag-valve-mask, intubate within 30 seconds, apply monitor electrodes and cables and check cardiac rhythm, apply gel pads and defibrillate safely, and finally, fold the cruciform triage card to show "RED", and attach it to the manikin. All the doctors completed these tasks, except for one, who could only intubate the manikin after several attempts. Nursing staff were asked to open and apply an oxygen mask, adjust oxygen flow, size and insert an oropharyngeal airway, ventilate the manikin using a bag-valve-mask, apply a pressure bandage to a limb, and fold the cruciform triage card to show "YELLOW", and attach it to the manikin. All the nurses completed these tasks. Operators reported varying degrees of difficulty, the most difficult tasks were those requiring fine movements or delicate control. Generally, operators found the butyl rubber gloves cumbersome. Communication difficulties were frequently reported. Although only intubation was formally timed, tasks were perceived to take longer. Some operators found the suits too warm and uncomfortable. Conclusion—Should the need arise, the TST-Sweden chemical protection suits would enable experienced doctors and nurses to perform lifesaving measures effectively

Screening agrochemicals as potential protectants of plants against ozone phytotoxicity.

Science.gov (United States)

Saitanis, Costas J; Lekkas, Dimitrios V; Agathokleous, Evgenios; Flouri, Fotini

2015-02-01

We tested seven contemporary agrochemicals as potential plant protectants against ozone phytotoxicity. In nine experiments, Bel-W3 tobacco plants were experienced weekly exposures to a) 80 nmol mol(-1) of ozone-enriched or ozone-free air in controlled environment chambers, b) an urban air polluted area, and c) an agricultural-remote area. Ozone caused severe leaf injury, reduced chlorophylls' and total carotenoids' content, and negatively affected photosynthesis and stomatal conductance. Penconazole, (35% ± 8) hexaconazole (28% ± 5) and kresoxim-methyl (28% ± 15) showed higher plants' protection (expressed as percentage; mean ± s.e.) against ozone, although the latter exhibited a high variability. Azoxystrobin (21% ± 15) showed lower protection efficacy and Benomyl (15% ± 9) even lower. Trifloxystrobin (7% ± 11) did not protect the plants at all. Acibenzolar-S-methyl + metalaxyl-M (Bion MX) (-6% ± 17) exhibited the higher variability and contrasting results: in some experiments it showed some protection while in others it intensified the ozone injury by causing phytotoxic symptoms on leaves, even in control plants. Copyright © 2014 Elsevier Ltd. All rights reserved.

Public health professionals' perceptions toward provision of health protection in England: a survey of expectations of Primary Care Trusts and Health Protection Units in the delivery of health protection.

Science.gov (United States)

Cosford, Paul A; O'Mahony, Mary; Angell, Emma; Bickler, Graham; Crawshaw, Shirley; Glencross, Janet; Horsley, Stephen S; McCloskey, Brian; Puleston, Richard; Seare, Nichola; Tobin, Martin D

2006-12-07

Effective health protection requires systematised responses with clear accountabilities. In England, Primary Care Trusts and the Health Protection Agency both have statutory responsibilities for health protection. A Memorandum of Understanding identifies responsibilities of both parties, but there is a potential lack of clarity about responsibility for specific health protection functions. We aimed to investigate professionals' perceptions of responsibility for different health protection functions, to inform future guidance for, and organisation of, health protection in England. We sent a postal questionnaire to all health protection professionals in England from the following groups: (a) Directors of Public Health in Primary Care Trusts; (b) Directors of Health Protection Units within the Health Protection Agency; (c) Directors of Public Health in Strategic Health Authorities and; (d) Regional Directors of the Health Protection Agency The response rate exceeded 70%. Variations in perceptions of who should be, and who is, delivering health protection functions were observed within, and between, the professional groups (a)-(d). Concordance in views of which organisation should, and which does deliver was high (> or =90%) for 6 of 18 health protection functions, but much lower (protection function was strongly correlated with the concordance (r = 0.65, P = 0.0038). Whilst we studied professionals' perceptions, rather than actual responses to incidents, our study suggests that there are important areas of health protection where consistent understanding of responsibility for delivery is lacking. There are opportunities to clarify the responsibility for health protection in England, perhaps learning from the approaches used for those health protection functions where we found consistent perceptions of accountability.

The route of infection determines Wolbachia antibacterial protection in Drosophila.

Science.gov (United States)

Gupta, Vanika; Vasanthakrishnan, Radhakrishnan B; Siva-Jothy, Jonathon; Monteith, Katy M; Brown, Sam P; Vale, Pedro F

2017-06-14

Bacterial symbionts are widespread among metazoans and provide a range of beneficial functions. Wolbachia -mediated protection against viral infection has been extensively demonstrated in Drosophila. In mosquitoes that are artificially transinfected with Drosophila melanogaster Wolbachia (wMel), protection from both viral and bacterial infections has been demonstrated. However, no evidence for Wolbachia -mediated antibacterial protection has been demonstrated in Drosophila to date. Here, we show that the route of infection is key for Wolbachia -mediated antibacterial protection. Drosophila melanogaster carrying Wolbachia showed reduced mortality during enteric-but not systemic-infection with the opportunist pathogen Pseudomonas aeruginosa Wolbachia -mediated protection was more pronounced in male flies and is associated with increased early expression of the antimicrobial peptide Attacin A , and also increased expression of a reactive oxygen species detoxification gene ( Gst D8 ). These results highlight that the route of infection is important for symbiont-mediated protection from infection, that Wolbachia can protect hosts by eliciting a combination of resistance and disease tolerance mechanisms, and that these effects are sexually dimorphic. We discuss the importance of using ecologically relevant routes of infection to gain a better understanding of symbiont-mediated protection. © 2017 The Authors.

Genetic Mechanisms of Coffee Extract Protection in a Caenorhabditis elegans Model of β-Amyloid Peptide Toxicity

OpenAIRE

Dostal, Vishantie; Roberts, Christine M.; Link, Christopher D.

2010-01-01

Epidemiological studies have reported that coffee and/or caffeine consumption may reduce Alzheimer's disease (AD) risk. We found that coffee extracts can similarly protect against β-amyloid peptide (Aβ) toxicity in a transgenic Caenorhabditis elegans Alzheimer's disease model. The primary protective component(s) in this model is not caffeine, although caffeine by itself can show moderate protection. Coffee exposure did not decrease Aβ transgene expression and did not need to be present during...

Performance Studies for Protection Against Asynchronous Dumps in the LHC

CERN Document Server

Kramer, T; Bracco, C; Goddard, B; Meddahi, M

2010-01-01

The LHC beam dump system has to safely dispose all beams in a wide energy range of 450 GeV to 7 TeV. A 3 ms abort gap in the beam structure for the switch-on of the extraction kicker field ideally allows a loss-free extraction under normal operating conditions. However, a low number of asynchronous beam aborts is to be expected from reliability calculations and from the first year's operational experience with the beam dump kickers. For such cases, MAD-X simulations including all optics and alignment errors have been performed to determine loss patterns around the LHC as a function of the position of the main protection elements in interaction region six. Special attention was paid to the beam load on the tungsten collimators which protect the triplets in the LHC experimental insertions, and the tracking results compared with semi-analytical numerical estimates. The simulations are also compared to the results of beam commissioning of these protection devices.

Study of the response of radiation protection monitors in terms of H*(10) in X radiation

International Nuclear Information System (INIS)

Nonato, Fernanda B.C.; Carvalho, Valdir S.; Vivolo, Vitor; Caldas, Linda V.E.

2009-01-01

The ambient dose equivalent, H * (10), is an operational quantity recommended by the International Commission of radiation Units and Measurements Report 39 for measurements in area monitoring. However, most of the monitoring instruments used in radiation protection in Brazil still use the old quantities exposure rate and absorbed dose rate. Therefore, it is necessary to study how to change the operational quantity to H * (10). In this work, the response of radiation protection monitoring detectors was studied in terms of H * (10) for different energies using standard X-rays (narrow beams) at the Calibration Laboratory of IPEN. (author)

Global Gene Expression Analysis of Cross-Protected Phenotype of Pectobacterium atrosepticum.

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Vladimir Gorshkov

Full Text Available The ability to adapt to adverse conditions permits many bacterial species to be virtually ubiquitous and survive in a variety of ecological niches. This ability is of particular importance for many plant pathogenic bacteria that should be able to exist, except for their host plants, in different environments e.g. soil, water, insect-vectors etc. Under some of these conditions, bacteria encounter absence of nutrients and persist, acquiring new properties related to resistance to a variety of stress factors (cross-protection. Although many studies describe the phenomenon of cross-protection and several regulatory components that induce the formation of resistant cells were elucidated, the global comparison of the physiology of cross-protected phenotype and growing cells has not been performed. In our study, we took advantage of RNA-Seq technology to gain better insights into the physiology of cross-protected cells on the example of a harmful phytopathogen, Pectobacterium atrosepticum (Pba that causes crop losses all over the world. The success of this bacterium in plant colonization is related to both its virulence potential and ability to persist effectively under various stress conditions (including nutrient deprivation retaining the ability to infect plants afterwards. In our previous studies, we showed Pba to be advanced in applying different adaptive strategies that led to manifestation of cell resistance to multiple stress factors. In the present study, we determined the period necessary for the formation of cross-protected Pba phenotype under starvation conditions, and compare the transcriptome profiles of non-adapted growing cells and of adapted cells after the cross-protective effect has reached the maximal level. The obtained data were verified using qRT-PCR. Genes that were expressed differentially (DEGs in two cell types were classified into functional groups and categories using different approaches. As a result, we portrayed

Numerical Study of Quench Protection for Fast-Ramping Accelerator Magnets

CERN Document Server

Schwerg, N; Mess, K-N; Russenschuck, S

2009-01-01

The quench module of the ROXIE field computation program has been presented at previous conferences. In this paper we discuss recently implemented features that allow quench simulation of fast-ramping superconducting magnets. As the reliability of quench detection during the ramps depends on the signal to noise ratio, we simulate the influence of detection thresholds and the propagation of undetected quenches during the ramps. We also study the effect of an increased copper content and the feasibility of a self-protected magnet surviving a powering cycle with an undetected quench and without quench heater firing or energy-extraction system.

Indium 111. Radiation protection

International Nuclear Information System (INIS)

Grafstroem, G.; Joensson, B.A.; Strand, S.E.

1989-01-01

The radiopharmaceutucal 111 In-oxine is used in labelling of different blood cells and proteins. Due to its liquid state, there is always a risk for contamination during handling procedures. The aim of the project was to evaluate the contamination risks, when using this radiopharmaceutical. The investigation includes calculations of the absorved dose to the skin after a contamination of 111 In-oxine, including the radionuclide impurity 114 In m / 114 In. Investigations of 288 protection gloves shows that there is always a risk for contamination, when working with 111 In-oxine. On the protection gloves, we found activities normally ranging from a 100 Bq up to a few kBq. Noticeable is the contamination on the vials, already before their use. Besides 111 In we found most of the radionuclides used in nuclear medicine, with activities up to tens of kBq. The radionuclide impurity was cleary detectable but below the recommended value. The penetration of 111 In-oxine protection gloves of latex was negligible. Measurements of penetration in skin was evaluated with two independent methods; in vivo using a surface barrier detector, and by autoradiography. The measured penetration was less than a few micrometers. Calculation from the experimental contamination values show that the absorbed dose to the basal cell layer could be in order of several Gy. (authors)

Privacy preservation and information security protection for patients' portable electronic health records.

Science.gov (United States)

Huang, Lu-Chou; Chu, Huei-Chung; Lien, Chung-Yueh; Hsiao, Chia-Hung; Kao, Tsair

2009-09-01

As patients face the possibility of copying and keeping their electronic health records (EHRs) through portable storage media, they will encounter new risks to the protection of their private information. In this study, we propose a method to preserve the privacy and security of patients' portable medical records in portable storage media to avoid any inappropriate or unintentional disclosure. Following HIPAA guidelines, the method is designed to protect, recover and verify patient's identifiers in portable EHRs. The results of this study show that our methods are effective in ensuring both information security and privacy preservation for patients through portable storage medium.

An Empirical Study on the Relationship between Investor Protection, Government Behavior, and Financial Development

Directory of Open Access Journals (Sweden)

Chien-Chi Chu

2017-11-01

Full Text Available We studied the relationship between investor protection, government behavior, and financial development using data covering six provinces (Guangdong, Jiangsu, Shandong, Zhejiang, Henan, and Sichuan and two provincial-level cities (Beijing and Shanghai in China for the period 2005–2014. Using panel data estimation techniques, we found that there is a positive relationship between investor protection and financial development; by contrast, highly-intense government intervention leads to more financial impediments. Moreover, government intervention in education could promote financial development through its contribution to having a higher amount of the fund supply. Our empirical findings have important implications for policy-makers in terms of reforming the capital market regulation.

Risk and Protective Factors for Intimate Partner Violence Against Women: Systematic Review and Meta-analyses of Prospective-Longitudinal Studies.

Science.gov (United States)

Yakubovich, Alexa R; Stöckl, Heidi; Murray, Joseph; Melendez-Torres, G J; Steinert, Janina I; Glavin, Calla E Y; Humphreys, David K

2018-07-01

The estimated lifetime prevalence of physical or sexual intimate partner violence (IPV) is 30% among women worldwide. Understanding risk and protective factors is essential for designing effective prevention strategies. To quantify the associations between prospective-longitudinal risk and protective factors and IPV and identify evidence gaps. We conducted systematic searches in 16 databases including MEDLINE and PsycINFO from inception to June 2016. The study protocol is registered with PROSPERO (CRD42016039213). We included published and unpublished studies available in English that prospectively analyzed any risk or protective factor(s) for self-reported IPV victimization among women and controlled for at least 1 other variable. Three reviewers were involved in study screening. One reviewer extracted estimates of association and study characteristics from each study and 2 reviewers independently checked a random subset of extractions. We assessed study quality with the Cambridge Quality Checklists. When studies investigated the same risk or protective factor using similar measures, we computed pooled odds ratios (ORs) by using random-effects meta-analyses. We summarized heterogeneity with I 2 and τ 2 . We synthesized all estimates of association, including those not meta-analyzed, by using harvest plots to illustrate evidence gaps and trends toward negative or positive associations. Of 18 608 studies identified, 60 were included and 35 meta-analyzed. Most studies were based in the United States. The strongest evidence for modifiable risk factors for IPV against women were unplanned pregnancy (OR = 1.66; 95% confidence interval [CI] = 1.20, 1.31) and having parents with less than a high-school education (OR = 1.55; 95% CI = 1.10, 2.17). Being older (OR = 0.96; 95% CI = 0.93, 0.98) or married (OR = 0.93; 95% CI = 0.87, 0.99) were protective. To our knowledge, this is the first systematic, meta-analytic review of all risk and

Tourism Partnerships in Protected Areas: Exploring Contributions to Sustainability

Science.gov (United States)

Pfueller, Sharron L.; Lee, Diane; Laing, Jennifer

2011-10-01

Partnerships between natural-area managers and the tourism industry have been suggested to contribute to sustainability in protected areas. This article explores how important sustainability outcomes of partnerships are to their members, how well they are realised and the features of partnerships leading to their achievement. In 21 case studies in Australia, interviews ( n = 97) and surveys ( n = 100) showed that of 14 sustainability outcomes, improved understanding of protected areas values and improved biodiversity conservation were the most important. Other highly ranked outcomes were greater respect for culture, heritage, and/or traditions; improved quality of environmental conditions; social benefits to local communities; and improved economic viability of the protected area. Scores for satisfaction with outcomes were, like those for importance, all high but were less than those for importance for the majority, with improvement in quality of environmental conditions showing the largest gap. The satisfaction score exceeded that for importance only for increased competitiveness of the protected area as a tourist destination. "Brown" aspects of sustainability, i.e., decreased waste or energy use, were among the lowest-scoring outcomes for both importance and satisfaction. The most important factor enabling sustainability outcomes was provision of benefits to partnership members. Others were increased financial support, inclusiveness, supportive organisational and administrative arrangements, direct involvement of decision makers, partnership maturity, creation of new relationships, decreased conflict, and stimulation of innovation. Improving sustainability outcomes, therefore, requires maintaining these partnership attributes and also increasing emphasis on reducing waste and resource use.

Protection of intestinal anastomoses in septic environment with peritoneal graft and polyglycolic acid mesh: an experimental study.

Science.gov (United States)

Dilek, O N; Bakir, B; Dilek, F H; Demirel, H; Yiğit, M F

1996-01-01

We carried out an experimental study in dogs to evaluate the outcome of large bowel anastomosis with 6 stitches (Group C, n : 6) in a septic environment with protection by a polyglycolic acid (PGA) mesh (Group M, n : 12) or peritoneal graft (Group P, n : 12). Thirty dogs were used to compare the techniques. Two dogs in each group were re-operated after 3, 5, 7, 14, 28 and 90 days. They were evaluated for adhesion formation, lumen diameter (anastomotic index), clinical features, histologic appearance and quality of healing at the anastomotic sites. All dogs in group P and group M survived, whereas 2 dogs in the control group died of anastomotic leakage and 3 dogs were re-operated for anastomotic leakage and peritonitis. In group M, one dog was reoperated because of the anastomotic leakage and two dogs were reoperated because of the anastomotic stenosis. Also, 4 anastomoses showed evidence of moderate stenosis. In group P, three anastomoses were graded as minimal stenosis. Histopathologic evaluation showed more complete epithelization, less inflammation, and less adhesion in group P than group M. We could not find any study in the literature that described and compared both techniques. We report here the results of such a study.

The application of the Monte Carlo code FLUKA in radiation protection studies for the large hadron collider

International Nuclear Information System (INIS)

Battistoni, Giuseppe; Broggi, Francesco; Brugger, Markus

2010-01-01

The multi-purpose particle interaction and transport code FLUKA is integral part of all radiation protection studies for the design and operation of the Large Hadron Collider (LHC) at CERN. It is one of the very few codes available for this type of calculations which is capable to calculate in one and the same simulation proton-proton and heavy ion collisions at LHC energies as well as the entire hadronic and electromagnetic particle cascade initiated by secondary particles in detectors and beam-line components from TeV energies down to energies of thermal neutrons. The present paper reviews these capabilities of FLUKA in giving details of relevant physics models along with examples of radiation protection studies for the LHC such as shielding studies for underground areas occupied by personnel during LHC operation and the simulation of induced radioactivity around beam loss points. Integral part of the FLUKA development is a careful benchmarking of specific models as well as the code performance in complex, real life applications which is demonstrated with examples of studies relevant to radiation protection at the LHC. (author)

Active immunizations with peptide-DC vaccines and passive transfer with antibodies protect neutropenic mice against disseminated candidiasis.

Science.gov (United States)

Xin, Hong

2016-01-04

We previously report that peptide-pulsed dendritic cell (DC) vaccination, which targeting two peptides (Fba and Met6) expressed on the cell surface of Candida albicans, can induce high degree of protection against disseminated candidiasis in immunocompetent mice. Passive transfer of immune sera from the peptide immunized mice or peptide-related monoclonal antibodies demonstrated that protection was medicated by peptide-specific antibodies. In this study the efficacy of active and passive immunization against disseminated candidiasis was tested in mice with cyclophosphamide-induced neutropenia. Peptide-DC vaccines were given to mice prior to induction of neutropenia. We show active immunization with either Fba or Met6 peptide-DC vaccine significantly improved the survival and reduced the fungal burden of disseminated candidiasis in those immunocompromised mice. Importantly, we show that administration of two protective monoclonal antibodies also protect neutropenic mice against the disease, implying possibility of developing a successful passive immunotherapy strategy to treat the disease and protect against disseminated candidiasis. The results of this study are crucial as they address the fundamental questions as to whether the synthetic peptide vaccine induced immunity protects the host during a neutropenic episode. We anticipate that this peptide-vaccine study will serve as the foundation of future investigations into new peptide vaccines comprised of cell surface peptides from other medically important Candida species, as well as other fungi. Copyright © 2015 Elsevier Ltd. All rights reserved.

Active Immunizations with Peptide-DC Vaccines and Passive Transfer with Antibodies Protect Neutropenic Mice against Disseminated Candidiasis

Science.gov (United States)

Xin, Hong

2015-01-01

We previously report that peptide-pulsed dendritic cell (DC) vaccination, which targeting two peptides (Fba and Met6) expressed on the cell surface of Candida albicans, can induce high degree of protection against disseminated candidiasis in immunocompetent mice. Passive transfer of immune sera from the peptide immunized mice or peptide-related monoclonal antibodies demonstrated that protection was medicated by peptide-specific antibodies. In this study the efficacy of active and passive immunization against disseminated candidiasis was tested in mice with cyclophosphamide-induced neutropenia. Peptide-DC vaccines were given to mice prior to induction of neutropenia. We show active immunization with either Fba or Met6 peptide-DC vaccine significantly improved the survival and reduced the fungal burden of disseminated candidiasis in those immunocompromised mice. Importantly, we show that administration of two protective monoclonal antibodies also protect neutropenic mice against the disease, implying possibility of developing a successful passive immunotherapy strategy to treat the disease and protect against disseminated candidiasis. The results of this study are crucial as they address the fundamental questions as to whether the synthetic peptide vaccine induced immunity protects the host during a neutropenic episode. We anticipate that this peptide-vaccine study will serve as the foundation of future investigations into new peptide vaccines comprised of cell surface peptides from other medically important Candida species, as well as other fungi. PMID:26620842

Radiation Protection in Medical Physics : Proceedings of the NATO Advanced Study Institute on Radiation Protection in Medical Physics Activities

CERN Document Server

Lemoigne, Yves

2011-01-01

This book introduces the fundamental aspects of Radiation Protection in Medical Physics and covers three main themes: General Radiation Protection Principles; Radiobiology Principles; Radiation Protection in Hospital Medical Physics. Each of these topics is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advances in the field. Some issues specific to the individual techniques are also treated, e.g. calculation of patient dose as well as that of workers in hospital, optimisation of equipment used, shielding design of radiation facilities, radiation in oncology such as use of brachytherapy in gynecology or interventional procedures. All topics are presented with didactical language and style, making this book an appropriate reference for students and professionals seeking a comprehensive introduction to the field as well as a reliable overview of the most recent developments.

Attenuation of earmuffs used simultaneously with respiratory protective devices

Directory of Open Access Journals (Sweden)

Emil Kozłowski

2017-06-01

Full Text Available Background: In the work environment, apart from the noise, employees may be exposed to other harmful factors. Therefore, they wear hearing protectors and other personal protective equipment. The aim of the study was to determine whether simultaneous use of earmuffs and respiratory protective devices affects the attenuation of earmuffs. Material and Methods: The study was conducted in laboratory conditions using the subjective REAT (Real Ear Attenuation at Threshold and objective MIRE (Microphone in Real Ear methods. The REAT method was used to measure sound attenuation of earmuffs, while MIRE was used to determine changes in attenuation of earmuffs due to the use of other personal protective equipment. Results: The study showed reduction in attenuation of earmuffs due to the use of a full face mask up to 20 dB. Using a full face mask causes that attenuation of earmuffs in the low frequency range is close to zero. Reduction in attenuation due to the use of half masks for complete with particle filters (half masks is 3–15 dB. Simultaneous use of earmuffs and filtering half masks makes small changes in attenuation not exceeding 3 dB. Conclusions: The study showed that full face masks give the greatest reduction in attenuation of earmuffs. On the other hand, the least reduction is observed in the case of filtering half masks. There is a significant difference between the reduction in attenuation of earmuffs worn with half masks for complete with particle filters because they may be equipped with different kind of the head strap. Med Pr 2017;68(3:349–361

The Protective Effect of Human Umbilical Cord Blood CD34+ Cells and Estradiol against Focal Cerebral Ischemia in Female Ovariectomized Rat: Cerebral MR Imaging and Immunohistochemical Study.

Directory of Open Access Journals (Sweden)

Ching-Chung Liang

Full Text Available Human umbilical cord blood derived CD34+ stem cells are reported to mediate therapeutic effects in stroke animal models. Estrogen was known to protect against ischemic injury. The present study wished to investigate whether the protective effect of CD34+ cells against ischemic injury can be reinforced with complemental estradiol treatment in female ovariectomized rat and its possible mechanism. Experiment 1 was to determine the best optimal timing of CD34+ cell treatment for the neuroprotective effect after 60-min middle cerebral artery occlusion (MCAO. Experiment 2 was to evaluate the adjuvant effect of 17β-estradiol on CD34+ cell neuroprotection after MCAO. Experiment 1 showed intravenous infusion with CD34+ cells before MCAO (pre-treatment caused less infarction size than those infused after MCAO (post-treatment on 7T magnetic resonance T2-weighted images. Experiment 2 revealed infarction size was most significantly reduced after CD34+ + estradiol pre-treatment. When compared with no treatment group, CD34+ + estradiol pre-treatment showed significantly less ADC reduction at 2 h and 2 d, less CBF reduction at 2 h and less hyperperfusion at 2 d. The immunoreactivity of c-Fos, c-Jun and GFAP was attenuated, and BDNF showed significant recovery from 2 h to 2 d after MCAO, especially after CD34+ + estradiol pre-treatment. The present study suggests pre-treatment with CD34+ cells with complemental estradiol can be most protective against ischemic injury, which may act through stabilization of cerebral hemodynamics and normalization of the expressions of immediate early genes and BDNF.

Quench protection studies of 11T 2-in-1 Nb$_{3}$Sn dipole models for LHC upgrades

OpenAIRE

Zlobin, AV; Chlachidze, G; Nobrega, F; Novitski, I; Karppinen, M

2014-01-01

CERN and FNAL are developing 11 T Nb3Sn dipole magnets for the LHC collimation system upgrade. Due to the large stored energy, protection of these magnets during a quench is a challenging problem. This paper reports the results of experimental studies of key quench protection parameters including longitudinal and radial quench propagation in the coil, coil heating due to a quench, and energy extraction and quench-back effect. The studies were performed using a 1 m long 11 T Nb3Sn dipole coil ...

Sunburn protection as a function of sunscreen application thickness differs between high and low SPFs.