WorldWideScience

Sample records for strong impact parameter

  1. A connection between extremely strong damped Lyman-α systems and Lyman-α emitting galaxies at small impact parameters

    Science.gov (United States)

    Noterdaeme, P.; Petitjean, P.; Pâris, I.; Cai, Z.; Finley, H.; Ge, J.; Pieri, M. M.; York, D. G.

    2014-06-01

    We present a study of ~100 high redshift (z ~ 2-4) extremely strong damped Lyman-α systems (ESDLA, with N(H i) ≥ 0.5 × 1022cm-2) detected in quasar spectra from the Baryon Oscillation Spectroscopic Survey (BOSS) of the Sloan Digital Sky Survey (SDSS-III) Data Release 11. We study the neutral hydrogen, metal, and dust content of this elusive population of absorbers and confirm our previous finding that the high column density end of the N(H i) frequency distribution has a relatively shallow slope with power-law index -3.6, similar to what is seen from 21-cm maps in nearby galaxies. The stacked absorption spectrum indicates a typical metallicity ~1/20th solar, similar to the mean metallicity of the overall DLA population. The relatively small velocity extent of the low-ionisation lines suggests that ESDLAs do not arise from large-scale flows of neutral gas. The high column densities involved are in turn more similar to what is seen in DLAs associated with gamma-ray burst afterglows (GRB-DLAs), which are known to occur close to star-forming regions. This indicates that ESDLAs arise from a line of sight passing at very small impact parameters from the host galaxy, as observed in nearby galaxies. This is also supported by simple theoretical considerations and recent high-z hydrodynamical simulations. We strongly substantiate this picture by the first statistical detection of Ly α emission with ⟨LESDLA(Ly α)⟩ ≃ (0.6 ± 0.2) × 1042 erg s-1 in the core of ESDLAs (corresponding to about 0.1 L⋆ at z ~ 2-3), obtained through stacking the fibre spectra (of radius 1 ″ corresponding to ~8 kpc at z ~ 2.5). Statistical errors on the Ly α luminosity are of the order of 0.1 × 1042 erg s-1 but we caution that the measured Ly α luminosity may be overestimated by ~35% due to sky light residuals and/or FUV emission from the quasar host and that we have neglected flux-calibration uncertainties. We estimate a more conservative uncertainty of 0.2 × 1042 erg s-1. The

  2. Impact Effects Calculator. Orbital Parameters.

    Science.gov (United States)

    Glazachev, D.; Naroenkov, S.; Kartashova, A.; Turuntaev, I.; Svetsov, V.; Shuvalov, V.; Popova, O.; Podobnaya, E.

    2017-09-01

    Next-generation Impact Calculator for quick assessment of impact consequences is preparing. The estimates of impact effects are revised. The possibility to manipulate with the orbital parameters and to determine impact point is included.

  3. Jet quenching parameters in strongly coupled nonconformal gauge theories

    International Nuclear Information System (INIS)

    Buchel, Alex

    2006-01-01

    Recently Liu, Rajagopal, and Wiedemann (LRW) [H. Liu, K. Rajagopal, and U. A. Wiedemann, hep-ph/0605178.] proposed a first principle, nonperturbative quantum field theoretic definition of 'jet quenching parameter' q-circumflex used in models of medium-induced radiative parton energy loss in nucleus-nucleus collisions at RHIC. Relating q-circumflex to a short-distance behavior of a certain lightlike Wilson loop, they used gauge theory-string theory correspondence to evaluate q-circumflex for the strongly coupled N=4 SU(N c ) gauge theory plasma. We generalize analysis of LRW to strongly coupled nonconformal gauge theory plasma. We find that a jet quenching parameter is gauge theory specific (not universal). Furthermore, it appears its value increases as the number of effective adjoint degrees of freedom of a gauge theory plasma increases

  4. Measurement of strong interaction parameters in antiprotonic hydrogen and deuterium

    CERN Document Server

    Augsburger, M A; Borchert, G L; Chatellard, D; Egger, J P; El-Khoury, P; Gorke, H; Gotta, D; Hauser, P R; Indelicato, P J; Kirch, K; Lenz, S; Siems, T; Simons, L M

    1999-01-01

    In the PS207 experiment at CERN, X-rays from antiprotonic hydrogen and deuterium have been measured at low pressure. The strong interaction shift and the broadening of the K/sub alpha / transition in antiprotonic hydrogen were $9 determined. Evidence was found for the individual hyperfine components of the protonium ground state. (7 refs).

  5. Orientation and impact-parameter dependence of dissociative ionization of H2 by slow ion impact

    International Nuclear Information System (INIS)

    Afaneh, F; Schmidt, L Ph H; Schoeffler, M; Stiebing, K E; Al-Jundi, J; Schmidt-Boecking, H; Doerner, R

    2007-01-01

    We have used the cold target recoil ion momentum spectroscopy imaging technique to investigate dissociative ionization of H 2 by 25 keV proton impact. A kinematically complete picture of the dissociative ionization dynamics for slow proton collision has been obtained. The results show a strong impact-parameter dependence of the fragmentation process of H 2 . This clearly emerged in the energy distributions of the H + ions generated for different impact parameters. At large impact parameters the H + ions equally share the energy liberated in the collision whereas at small impact parameters, the energy sharing is quite asymmetric. We also observed a strong dependence of the electron emission on molecular alignment. The momentum distribution of the emitted electron generated for a fixed-in-space H 2 molecule displays that the electrons are more likely to be emitted perpendicular to the molecular axis

  6. Quantum correlations responsible for remote state creation: strong and weak control parameters

    Science.gov (United States)

    Doronin, S. I.; Zenchuk, A. I.

    2017-03-01

    We study the quantum correlations between the two remote qubits (sender and receiver) connected by the transmission line (homogeneous spin-1/2 chain) depending on the parameters of the sender's and receiver's initial states (control parameters). We consider two different measures of quantum correlations: the entanglement (a traditional measure) and the informational correlation (based on the parameter exchange between the sender and receiver). We find the domain in the control parameter space yielding (i) zero entanglement between the sender and receiver during the whole evolution period and (ii) non-vanishing informational correlation between the sender and receiver, thus showing that the informational correlation is responsible for the remote state creation. Among the control parameters, there are the strong parameters (which strongly effect the values of studied measures) and the weak ones (whose effect is negligible), therewith the eigenvalues of the initial state are given a privileged role. We also show that the problem of small entanglement (concurrence) in quantum information processing is similar (in certain sense) to the problem of small determinants in linear algebra. A particular model of 40-node spin-1/2 communication line is presented.

  7. Multiple Moving Targets Detection and Parameters Estimation in Strong Reverberation Environments

    Directory of Open Access Journals (Sweden)

    Ge Yu

    2016-01-01

    Full Text Available This paper considers the problem of multiple moving targets detection and parameters estimation (direction of arrival and range in strong reverberation environments. As reverberation has a strong correlation with target echo, the performance of target detection and parameters estimation is significantly degraded in practical underwater environments. In this paper, we utilize two uniform circular arrays to receive plane wave of the linear frequency modulation signal reflected from far-field targets. On the basis of received signal, we build a variance matrix of multiple beams by using modal decomposition, conventional beamforming, and fractional Fourier transform (FrFT. We then propose a novel detection method and an estimation method of parameters based on the constructed image. A significant feature of the proposed methods is that our design does not involve any a priori knowledge about targets number and parameters of marine environments. Finally, we demonstrate via numerical simulation examples that the detection probability and the accuracy of estimated parameters of the proposed method are higher than the existing methods in both low signal-to-reverberation ratio and signal-to-noise ratio environment.

  8. Uncertainties in Parameters Estimated with Neural Networks: Application to Strong Gravitational Lensing

    Science.gov (United States)

    Perreault Levasseur, Laurence; Hezaveh, Yashar D.; Wechsler, Risa H.

    2017-11-01

    In Hezaveh et al. we showed that deep learning can be used for model parameter estimation and trained convolutional neural networks to determine the parameters of strong gravitational-lensing systems. Here we demonstrate a method for obtaining the uncertainties of these parameters. We review the framework of variational inference to obtain approximate posteriors of Bayesian neural networks and apply it to a network trained to estimate the parameters of the Singular Isothermal Ellipsoid plus external shear and total flux magnification. We show that the method can capture the uncertainties due to different levels of noise in the input data, as well as training and architecture-related errors made by the network. To evaluate the accuracy of the resulting uncertainties, we calculate the coverage probabilities of marginalized distributions for each lensing parameter. By tuning a single variational parameter, the dropout rate, we obtain coverage probabilities approximately equal to the confidence levels for which they were calculated, resulting in accurate and precise uncertainty estimates. Our results suggest that the application of approximate Bayesian neural networks to astrophysical modeling problems can be a fast alternative to Monte Carlo Markov Chains, allowing orders of magnitude improvement in speed.

  9. Mechanical Ventilation-induced Diaphragm Atrophy Strongly Impacts Clinical Outcomes.

    Science.gov (United States)

    Goligher, Ewan C; Dres, Martin; Fan, Eddy; Rubenfeld, Gordon D; Scales, Damon C; Herridge, Margaret S; Vorona, Stefannie; Sklar, Michael C; Rittayamai, Nuttapol; Lanys, Ashley; Murray, Alistair; Brace, Deborah; Urrea, Cristian; Reid, W Darlene; Tomlinson, George; Slutsky, Arthur S; Kavanagh, Brian P; Brochard, Laurent J; Ferguson, Niall D

    2018-01-15

    Diaphragm dysfunction worsens outcomes in mechanically ventilated patients, but the clinical impact of potentially preventable changes in diaphragm structure and function caused by mechanical ventilation is unknown. To determine whether diaphragm atrophy developing during mechanical ventilation leads to prolonged ventilation. Diaphragm thickness was measured daily by ultrasound in adults requiring invasive mechanical ventilation; inspiratory effort was assessed by thickening fraction. The primary outcome was time to liberation from ventilation. Secondary outcomes included complications (reintubation, tracheostomy, prolonged ventilation, or death). Associations were adjusted for age, severity of illness, sepsis, sedation, neuromuscular blockade, and comorbidity. Of 211 patients enrolled, 191 had two or more diaphragm thickness measurements. Thickness decreased more than 10% in 78 patients (41%) by median Day 4 (interquartile range, 3-5). Development of decreased thickness was associated with a lower daily probability of liberation from ventilation (adjusted hazard ratio, 0.69; 95% confidence interval [CI], 0.54-0.87; per 10% decrease), prolonged ICU admission (adjusted duration ratio, 1.71; 95% CI, 1.29-2.27), and a higher risk of complications (adjusted odds ratio, 3.00; 95% CI, 1.34-6.72). Development of increased thickness (n = 47; 24%) also predicted prolonged ventilation (adjusted duration ratio, 1.38; 95% CI, 1.00-1.90). Decreasing thickness was related to abnormally low inspiratory effort; increasing thickness was related to excessive effort. Patients with thickening fraction between 15% and 30% (similar to breathing at rest) during the first 3 days had the shortest duration of ventilation. Diaphragm atrophy developing during mechanical ventilation strongly impacts clinical outcomes. Targeting an inspiratory effort level similar to that of healthy subjects at rest might accelerate liberation from ventilation.

  10. CORRELATION ANALYSIS OF VEHICLE FRONTAL IMPACT PARAMETERS

    Directory of Open Access Journals (Sweden)

    Josef Mík

    2017-12-01

    Full Text Available The article considers a possible improvement of road vehicle safety by using eCall – a system which initiates an emergency call in case of traffic accident. A possible way of better description of a frontal impact accident of a vehicle is examined and enriched by the information from the onboard e-call unit. In this article, we analyze results of frontal crash tests with different types of barriers and overlapping area and look for the correlation between the individual vehicle and collision parameters in order to provide a better description of the severity of the accident by the eCall system. The relation among the selected parameters is described using the correlation analysis.

  11. Estimation of a collision impact parameter

    International Nuclear Information System (INIS)

    Shmatov, S.V.; Zarubin, P.I.

    2001-01-01

    We demonstrate that the nuclear collision geometry (i.e. impact parameter) can be determined in an event-by-event analysis by measuring the transverse energy flow in the pseudorapidity region 3≤|η|≤5 with a minimal dependence on collision dynamics details at the LHC energy scale. Using the HIJING model we have illustrated our calculation by a simulation of events of nucleus-nucleus interactions at the c.m.s. energy from 1 up to 5.5 TeV per nucleon and various types of nuclei

  12. Parameter study of high-β tokamak reactors with circular and strongly elongated cross section

    International Nuclear Information System (INIS)

    Herold, H.

    1977-05-01

    A simplified reactor model is used to study the influence of critical β-values on economy parameters and dimensions of possible long time pulsed tokamak reactors. Various betas deduced from stability and equilibrium MHD theory are introduced and put into the scaling in context with technological constraints, as maximum B-field, core constraint, maximum wall loading a.o. The plasma physical concepts treated comprise circular and strongly elongated cross section and approximated FCT equilibria. The computational results are presented as plots of possible economy parameter ranges (magnet energy, wall loading, volumina, investment costs per unit power) dependent on β for suitably chosen hierarchies of the constraints. - A burn time reduction by the build ups of α-pressure may be possible for the pressure profile sensitive high-β equilibria (FCT). Burn times in the 1O sec range, resulting from simple estimates, would about cancel the economic advantages of reactors with high-β equilibria compared to a β = 5% standardreactor (UWMAK I). (orig.) [de

  13. Orientation and impact-parameter dependence of dissociative ionization of H{sub 2} by slow ion impact

    Energy Technology Data Exchange (ETDEWEB)

    Afaneh, F [Physics Department, Hashemite University, PO Box 150459, Zarqa 13115 (Jordan); Schmidt, L Ph H [Institut fuer Kernphysik, Max-von-Laue-Str. 1, 60438 Frankfurt (Germany); Schoeffler, M [Institut fuer Kernphysik, Max-von-Laue-Str. 1, 60438 Frankfurt (Germany); Stiebing, K E [Institut fuer Kernphysik, Max-von-Laue-Str. 1, 60438 Frankfurt am Main (Germany); Al-Jundi, J [Physics Department, Hashemite University, PO Box 150459, Zarqa 13115 (Jordan); Schmidt-Boecking, H [Institut fuer Kernphysik, Max-von-Laue-Str. 1, 60438 Frankfurt (Germany); Doerner, R [Institut fuer Kernphysik, Max-von-Laue-Str. 1, 60438 Frankfurt (Germany)

    2007-09-14

    We have used the cold target recoil ion momentum spectroscopy imaging technique to investigate dissociative ionization of H{sub 2} by 25 keV proton impact. A kinematically complete picture of the dissociative ionization dynamics for slow proton collision has been obtained. The results show a strong impact-parameter dependence of the fragmentation process of H{sub 2}. This clearly emerged in the energy distributions of the H{sup +} ions generated for different impact parameters. At large impact parameters the H{sup +} ions equally share the energy liberated in the collision whereas at small impact parameters, the energy sharing is quite asymmetric. We also observed a strong dependence of the electron emission on molecular alignment. The momentum distribution of the emitted electron generated for a fixed-in-space H{sub 2} molecule displays that the electrons are more likely to be emitted perpendicular to the molecular axis.

  14. The limits on the strong Higgs sector parameters in the presence of new vector resonances

    Energy Technology Data Exchange (ETDEWEB)

    Gintner, Mikulas [University of Zilina, Physics Department, Zilina (Slovakia); Czech Technical University in Prague, Institute of Experimental and Applied Physics, Prague (Czech Republic); Juran, Josef [Czech Technical University in Prague, Institute of Experimental and Applied Physics, Prague (Czech Republic); Silesian University in Opava, Institute of Physics, Opava (Czech Republic)

    2016-12-15

    In this paper, we investigate how the LHC data limit the Higgs-related couplings in the effective description of a strongly interacting extension of the Standard model. The Higgs boson is introduced as a scalar composite state and it is followed in the mass hierarchy by an SU(2) triplet of vector composites. The limits are calculated from the constraints obtained in the recent ATLAS+CMS combined analysis of the data from 2011 and 2012. We find that the data prefer the scenario where the Higgs couplings to the electroweak gauge bosons differ from its couplings to the vector triplet. We also investigate the unitarity limits of the studied effective model for the experimentally preferred values of the Higgs couplings. We find from the ππ → ππ scattering amplitudes that for the vector resonance masses between one and two TeV significant portions of the experimentally allowed regions are well below the unitarity limit. We also evaluate how the existing ATLAS and CMS Run-2 data restrict our model with the upper bounds on the resonance production cross section times its branching ratio for various decay channels. The masses in the range 1 TeV ≤ M{sub ρ} ≤ 2 TeV are not excluded in parts or even full parameter space of our theory. (orig.)

  15. Simulation of strong ground motion parameters of the 1 June 2013 Gulf of Suez earthquake, Egypt

    Science.gov (United States)

    Toni, Mostafa

    2017-06-01

    This article aims to simulate the ground motion parameters of the moderate magnitude (ML 5.1) June 1, 2013 Gulf of Suez earthquake, which represents the largest instrumental earthquake to be recorded in the middle part of the Gulf of Suez up to now. This event was felt in all cities located on both sides of the Gulf of Suez, with minor damage to property near the epicenter; however, no casualties were observed. The stochastic technique with the site-dependent spectral model is used to simulate the strong ground motion parameters of this earthquake in the cities located at the western side of the Gulf of Suez and north Red Sea namely: Suez, Ain Sokhna, Zafarana, Ras Gharib, and Hurghada. The presence of many tourist resorts and the increase in land use planning in the considered cities represent the motivation of the current study. The simulated parameters comprise the Peak Ground Acceleration (PGA), Peak Ground Velocity (PGV), and Peak Ground Displacement (PGD), in addition to Pseudo Spectral Acceleration (PSA). The model developed for ground motion simulation is validated by using the recordings of three accelerographs installed around the epicenter of the investigated earthquake. Depending on the site effect that has been determined in the investigated areas by using geotechnical data (e.g., shear wave velocities and microtremor recordings), the investigated areas are classified into two zones (A and B). Zone A is characterized by higher site amplification than Zone B. The ground motion parameters are simulated at each zone in the considered areas. The results reveal that the highest values of PGA, PGV, and PGD are observed at Ras Gharib city (epicentral distance ∼ 11 km) as 67 cm/s2, 2.53 cm/s, and 0.45 cm respectively for Zone A, and as 26.5 cm/s2, 1.0 cm/s, and 0.2 cm respectively for Zone B, while the lowest values of PGA, PGV, and PGD are observed at Suez city (epicentral distance ∼ 190 km) as 3.0 cm/s2, 0.2 cm/s, and 0.05 cm/s respectively for Zone A

  16. Strong Showing for AGU Journals in 2009 Impact Factors

    Science.gov (United States)

    Cook, Bill

    2010-06-01

    AGU publishes great science, which is recognized in several ways. One of the most widely recognized is from Thomson Reuters, which provides the Journal Citation Report (JCR) each year as a component of the Web of Science®. JCR reports on several measures of journal usage, including a journal's Eigenfactor score, its Article Influence score, its Impact Factor, and its rank within a cohort of similar journals. According to the 2009 statistics released last week, AGU again has outperformed its larger competitors. For the twelfth time, two different AGU titles hold the top rank in their categories, and AGU titles hold the second spot in two other categories and third in two more.

  17. Slow Impacts on Strong Targets Bring on the Heat

    Science.gov (United States)

    Melosh, H. J.; Ivanov, B. A.

    2018-03-01

    An important new paper by Kurosawa and Genda (2017, https://doi.org/10.1002/2017GL076285) reports a previously overlooked source of heating in low velocity meteorite impacts. Plastic deformation of the pressure-strengthened rocks behind the shock front dissipates energy, which appears as heat in addition to that generated across the shock wave itself. This heat source has surprisingly escaped explicit attention for decades: First, because it is minimized in the geometry typically chosen for laboratory experiments; and second because it is most important in rocks, and less so for the metals usually used in experiments. Nevertheless, modern numerical computer codes that include strength do compute this heating correctly. This raises the philosophical question of whether we can claim to understand some process just because our computer codes compute the results correctly.

  18. Moscow: A natural testing area for strong warming impact assessment

    Science.gov (United States)

    Klimenko, V. V.; Tereshin, A. G.; Kasilova, E. V.

    2017-11-01

    In recent decades, Moscow has experienced the impact of remarkable climate changes on a scale that has significantly exceeded the climate changes in most of the world's populated regions. Analysis of operation of the Moscow energy system under these new conditions has allowed us to reveal that the climate changes have determined alleviation of energy supply requirements during the cold season, contributed to decreased overall energy consumption, and led to reduced seasonal irregularity of the annual power load schedule. The results of this study allow us to conclude that an increase in the annual-mean temperature by 3-4°C in temperate and cold climate zones for continental regions brings no apparent negative consequences for operation of the energy system.

  19. Empirical relations between instrumental and seismic parameters of some strong earthquakes of Colombia

    International Nuclear Information System (INIS)

    Marin Arias, Juan Pablo; Salcedo Hurtado, Elkin de Jesus; Castillo Gonzalez, Hardany

    2008-01-01

    In order to establish the relationships between macroseismic and instrumental parameters, macroseismic field of 28 historical earthquakes that produced great effects in the Colombian territory were studied. The integration of the parameters was made by using the methodology of Kaussel and Ramirez (1992), for great Chilean earthquakes; Kanamori and Anderson (1975) and Coppersmith and Well (1994) for world-wide earthquakes. Once determined the macroseismic and instrumental parameters it was come to establish the model of the source of each earthquake, with which the data base of these parameters was completed. For each earthquake parameters related to the local and normal macroseismic epicenter were complemented, depth of the local and normal center, horizontal extension of both centers, vertical extension of the normal center, model of the source, area of rupture. The obtained empirical relations from linear equations, even show behaviors very similar to the found ones by other authors for other regions of the world and to world-wide level. The results of this work allow establishing that certain mutual non compatibility exists between the area of rupture and the length of rupture determined by the macroseismic methods, with parameters found with instrumental data like seismic moment, Ms magnitude and Mw magnitude.

  20. Impact of staffing parameters on operational reliability

    International Nuclear Information System (INIS)

    Hahn, H.A.; Houghton, F.K.

    1993-01-01

    This paper reports on a project related to human resource management of the Department of Energy's (DOE's) High-Level Waste (HLW) Tank program. Safety and reliability of waste tank operations is impacted by several issues, including not only the design of the tanks themselves, but also how operations and operational personnel are managed. As demonstrated by management assessments performed by the Tiger Teams, DOE believes that the effective use of human resources impacts environment safety, and health concerns. For the of the current paper, human resource management activities are identified as ''Staffing'' and include the of developing the functional responsibilities and qualifications of technical and administrative personnel. This paper discusses the importance of staff plans and management in the overall view of safety and reliability. The work activities and procedures associated with the project, a review of the results of these activities, including a summary of the literature and a preliminary analysis of the data. We conclude that although identification of staffing issues and the development of staffing plans contributes to the overall reliability and safety of the HLW tanks, the relationship is not well understood and is in need of further development

  1. Impact of staffing parameters on operational reliability

    International Nuclear Information System (INIS)

    Hahn, H.A.; Houghton, F.K.

    1993-01-01

    This paper reports on a project related to human resource management of the Department of Energy (DOEs) High-Level Waste (HLW) Tank program. Safety and reliability of waste tank operations is impacted by several issues, including not only the design of the tanks themselves, but also how operations and operational personnel are managed. As demonstrated by management assessments performed by the Tiger Teams, DOE believes that the effective use of human resources impacts environment, safety, and health concerns. For the purposes of the current paper, human resource management activities are identified as 'Staffing' and include the process of developing the functional responsibilities and qualifications of technical and administrative personnel. This paper discusses the importance of staff plans and management in the overall view of safety and reliability, the work activities and procedures associated with the project, a review of the results of these activities, including a summary of the literature and a preliminary analysis of the data. We conclude that, although identification of staffing issues and the development of staffing plans contributes to the overall reliability and safety of the HLW tanks, the relationship is not well understood and is in need of further development

  2. The Aftershock Risk Index - quantification of aftershock impacts during ongoing strong-seismic sequences

    Science.gov (United States)

    Schaefer, Andreas; Daniell, James; Khazai, Bijan; Wenzel, Friedemann

    2016-04-01

    The occurrence and impact of strong earthquakes often triggers the long-lasting impact of a seismic sequence. Strong earthquakes are generally followed by many aftershocks or even strong subsequently triggered ruptures. The Nepal 2015 earthquake sequence is one of the most recent examples where aftershocks significantly contributed to human and economic losses. In addition, rumours about upcoming mega-earthquakes, false predictions and on-going cycles of aftershocks induced a psychological burden on the society, which caused panic, additional casualties and prevented people from returning to normal life. This study shows the current phase of development of an operationalised aftershock intensity index, which will contribute to the mitigation of aftershock hazard. Hereby, various methods of earthquake forecasting and seismic risk assessments are utilised and an integration of the inherent aftershock intensity is performed. A spatio-temporal analysis of past earthquake clustering provides first-hand data about the nature of aftershock occurrence. Epidemic methods can additionally provide time-dependent variation indices of the cascading effects of aftershock generation. The aftershock hazard is often combined with the potential for significant losses through the vulnerability of structural systems and population. A historical database of aftershock socioeconomic effects from CATDAT has been used in order to calibrate the index based on observed impacts of historical events and their aftershocks. In addition, analytical analysis of cyclic behaviour and fragility functions of various building typologies are explored. The integration of many different probabilistic computation methods will provide a combined index parameter which can then be transformed into an easy-to-read spatio-temporal intensity index. The index provides daily updated information about the probability of the inherent seismic risk of aftershocks by providing a scalable scheme fordifferent aftershock

  3. Impact of physico-chemical parameters on the physiological growth ...

    African Journals Online (AJOL)

    Impact of physico-chemical parameters on the physiological growth of Arthrospira (Spirulina platensis) exogenous strain UTEXLB2340. Yahia Mustafa A Fagiri, Aisha Salleh, Saifeldin Ahmed F El-Nagerabi ...

  4. Influence of the impact parameter on the heavy-ion fusion process

    International Nuclear Information System (INIS)

    Fonte, R.; Insolia, A.

    1984-01-01

    A simple interpretation of the existence of a l-window in complete fusion reactions between heavy ions is suggested. The dependence of the calculated impact parameters leading to fusion vs. Vsub(rel)/C exhibits strong analogies with the findings in the collision of two water droplets

  5. Determination of impact parameter by means of a neural network

    International Nuclear Information System (INIS)

    Haddad, F.; Hagel, K.; Li, J.; Mdeiwayeh, N.; Natowitz, J.B.; Wada, R.; Xiao, B.; David, C.; Freslier, M.; Aichelin, J.

    1997-01-01

    By occurrence of 4π detectors it becomes increasingly difficult to analyse the experimental data without resorting to a theoretical model. Unfortunately one of the key parameter of these models is the impact parameter which is hard to extract experimentally. In this paper a neural network was used to determine the impact parameter in 40 Ca + 40 Ca reactions. Utilization of a neural network is a process implying two stages: an apprenticeship step followed by an utilization stage. During the first stage the network parameters are determined by minimizing the difference between the network output and the expected theoretical output from a trial game. In our case we have used the QMD model coupled to Gemini to generate the 1000 events constituting our trial game. The analysis of Amphora 40 Ca + 40 Ca data at 35 MeV per nucleon using a neural network shows two well separated classes of events among the selected 'complete' events

  6. Pre-equilibrium particles emission: impact parameter and incident energy influence

    International Nuclear Information System (INIS)

    Peter, J.; Cussol, D.; Bizard, G.; Brou, R.; Louvel, M.; Patry, J.P.; Regimbart, R.; Steckmeyer, J.C.; Tamain, B.; Motobayashi, T.; Cassagnou, Y.; Legrain, R.; Hagel, K.; Jin, G.M.; Motobayashi, T.

    1990-01-01

    Charged particles and fragments emitted in reactions between 40 Ar at 45 and 65 MeV/u and an 27 Al target have been detected in a geometry close to 4 π in the center of mass. A new global variable, the average parallel velocity, has been used to sort the events as a function of the impact parameter value. For particles with Z = 1 and 2, a pre-equilibrium component is present. Its multiplicity increases strongly when the impact parameter value decreases, and reaches 7 in head-on reactions [fr

  7. STRONG SOLAR WIND DYNAMIC PRESSURE PULSES: INTERPLANETARY SOURCES AND THEIR IMPACTS ON GEOSYNCHRONOUS MAGNETIC FIELDS

    International Nuclear Information System (INIS)

    Zuo, Pingbing; Feng, Xueshang; Wang, Yi; Xie, Yanqiong; Xu, Xiaojun

    2015-01-01

    In this investigation, we first present a statistical result of the interplanetary sources of very strong solar wind dynamic pressure pulses (DPPs) detected by WIND during solar cycle 23. It is found that the vast majority of strong DPPs reside within solar wind disturbances. Although the variabilities of geosynchronous magnetic fields (GMFs) due to the impact of positive DPPs have been well established, there appears to be no systematic investigations on the response of GMFs to negative DPPs. Here, we study both the decompression effects of very strong negative DPPs and the compression from strong positive DPPs on GMFs at different magnetic local time sectors. In response to the decompression of strong negative DPPs, GMFs on the dayside near dawn and near dusk on the nightside, are generally depressed. But near the midnight region, the responses of GMF are very diverse, being either positive or negative. For part of the events when GOES is located at the midnight sector, the GMF is found to abnormally increase as the result of magnetospheric decompression caused by negative DPPs. It is known that under certain conditions magnetic depression of nightside GMFs can be caused by the impact of positive DPPs. Here, we find that a stronger pressure enhancement may have a higher probability of producing the exceptional depression of GMF at the midnight region. Statistically, both the decompression effect of strong negative DPPs and the compression effect of strong positive DPPs depend on the magnetic local time, which are stronger at the noon sector

  8. Computational code in atomic and nuclear quantum optics: Advanced computing multiphoton resonance parameters for atoms in a strong laser field

    Science.gov (United States)

    Glushkov, A. V.; Gurskaya, M. Yu; Ignatenko, A. V.; Smirnov, A. V.; Serga, I. N.; Svinarenko, A. A.; Ternovsky, E. V.

    2017-10-01

    The consistent relativistic energy approach to the finite Fermi-systems (atoms and nuclei) in a strong realistic laser field is presented and applied to computing the multiphoton resonances parameters in some atoms and nuclei. The approach is based on the Gell-Mann and Low S-matrix formalism, multiphoton resonance lines moments technique and advanced Ivanov-Ivanova algorithm of calculating the Green’s function of the Dirac equation. The data for multiphoton resonance width and shift for the Cs atom and the 57Fe nucleus in dependence upon the laser intensity are listed.

  9. Dispersion parameters: impact on calculated reactor accident consequences

    Energy Technology Data Exchange (ETDEWEB)

    Aldrich, D.C.

    1979-01-01

    Much attention has been given in recent years to the modeling of the atmospheric dispersion of pollutants released from a point source. Numerous recommendations have been made concerning the choice of appropriate dispersion parameters. A series of calculations has been performed to determine the impact of these recommendations on the calculated consequences of large reactor accidents. Results are presented and compared in this paper.

  10. Luminescence model with quantum impact parameter for low energy ions

    CERN Document Server

    Cruz-Galindo, H S; Martínez-Davalos, A; Belmont-Moreno, E; Galindo, S

    2002-01-01

    We have modified an analytical model of induced light production by energetic ions interacting in scintillating materials. The original model is based on the distribution of energy deposited by secondary electrons produced along the ion's track. The range of scattered electrons, and thus the energy distribution, depends on a classical impact parameter between the electron and the ion's track. The only adjustable parameter of the model is the quenching density rho sub q. The modification here presented, consists in proposing a quantum impact parameter that leads to a better fit of the model to the experimental data at low incident ion energies. The light output response of CsI(Tl) detectors to low energy ions (<3 MeV/A) is fitted with the modified model and comparison is made to the original model.

  11. Automatic characterization of loose parts impact damage risk parameters

    International Nuclear Information System (INIS)

    Glass, S.W.; Phillips, J.M.

    1985-01-01

    Loose parts caught in the high-velocity flows of the reactor coolant fluid strike against nuclear steam supply system (NSSS) components and can cause significant damage. Loose parts monitor systems (LPMS) have been available for years to detect metal-to-metal impacts. Once detected, however, an assessment of the damage risk potential for leaving the part in the system versus shutting it down and removing the part must be made. The principal parameters used in the damage risk assessment are time delays between the first and subsequent sensor indications (used to assess the impact location) and a correlation between the waveform and the impact energy of the part (how hard the part impacted). These parameters are not well suited to simple automatic techniques. The task has historically been performed by loose parts diagnostic experts who base much of their evaluation on experience and subjective interpretation of impact data waveforms. Three of the principal goals in developing the Babcock and Wilcox (B and W) LPMS-III were (a) to develop an accurate automatic assessment for the time delays, (b) to develop an automatic estimate of the impact energy, and (c) to present the data in a meaningful manner to the operator

  12. Parameters for assessing the aquatic environmental impact of cosmetic products.

    Science.gov (United States)

    Vita, N A; Brohem, C A; Canavez, A D P M; Oliveira, C F S; Kruger, O; Lorencini, M; Carvalho, C M

    2018-05-01

    The cosmetic industry's growing concern about the impact of its supply chain on the environment, sustainability of raw materials, and biodiversity increases the need to ensure that the final product has a lower environmental impact. The objective of this review is to summarize and compare the information available from international organizations and legislation regarding the main criteria used to assess raw materials for aquatic toxicity, as well as the most suitable alternative methods for obtaining assessment parameters. Using the literature available in databases, a review of the scientific literature and international legislation, this work discusses and compares the parameters established by international organizations such as the Environmental Protection Agency (EPA) and Cradle to Cradle (C2C), as well as European legislation, namely, European Regulation 1272/2008, for assessing environmental impact. Defining the ecotoxicity parameters of the main classes of raw materials in rinse-off cosmetic products can enable the development of products that are more environmentally sustainable, prioritizing substances with less environmental impact. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. Impact parameter dynamics in quantum theory in large angle scattering

    International Nuclear Information System (INIS)

    Andriyanov, A.A.

    1975-01-01

    High energy behaviour of a free particle Green's function is studied for construction of the scattering amplitude. The main part of the Green's function is determined by eikonal scattering along the mean moment and by the total scattering along the transfered momentum. This ''impact'' approximation may be included as a first approximation in the iteration scheme for the scattering amplitude along the mean momentum, i.e. the ''impact'' perturbation theory. With the help of the ''impact'' approximation an expansion of the scattering amplitude in the impact parameter depending on interaction is obtained. These expansions are more correct than the eikonal expansions at large angle scattering. The results are illustrated grafically foe the exponential and the Yukawa potentials

  14. Sensitivity to the impact parameter of the multiparticle decay at intermediate energy

    International Nuclear Information System (INIS)

    Del Zoppo, A.; Alba, R.; Agodi, C.; Bellia, G.; Coniglione, R.; Finocchiaro, P.; Latora, V.; Loukachine, K.; Maiolino, C.; Migneco, E.; Peghaire, A.; Piattelli, P.; Santonocito, D.; Sapienza, P.

    1994-01-01

    The multiparticle decay in collisions induced by 44 MeV/nucleon 40 Ar and 132 Xe projectiles on several targets is studied using MEDEA 4π detection system. The impact parameter dependence of the charged particle multiplicity is determined. The dependence is strong in peripheral and midcentral collisions and becomes weaker in central collisions. The prediction of a molecular dynamics simulation is in agreement with the experiment

  15. Sensitivity to the impact parameter of the multiparticle decay at intermediate energy

    Energy Technology Data Exchange (ETDEWEB)

    Del Zoppo, A.; Alba, R.; Agodi, C.; Bellia, G.; Coniglione, R.; Finocchiaro, P.; Latora, V.; Loukachine, K.; Maiolino, C.; Migneco, E.; Peghaire, A.; Piattelli, P.; Santonocito, D.; Sapienza, P. (INFN-Laboratorio Nazionale del Sud, Via S. Sofia 44, 95123 Catania (Italy) Dipartimento di Fisica dell' Universita di Catania (Italy) Grand Accelerateur National d' Ions Lourds, Caen (France))

    1994-12-01

    The multiparticle decay in collisions induced by 44 MeV/nucleon [sup 40]Ar and [sup 132]Xe projectiles on several targets is studied using MEDEA 4[pi] detection system. The impact parameter dependence of the charged particle multiplicity is determined. The dependence is strong in peripheral and midcentral collisions and becomes weaker in central collisions. The prediction of a molecular dynamics simulation is in agreement with the experiment.

  16. Impact of Oscillation Parameters on Surface Quality of Cast Billets

    Directory of Open Access Journals (Sweden)

    Cibulka J.

    2016-03-01

    Full Text Available The paper is focused on impact of different oscillation parameters on surface quality of peritectic steel grades cast into billets 150x150 mm. Hydraulic oscillation used for this purpose was temporarily installed on one strand of the billet caster. Hydraulic oscillation enables, in comparison to ordinary used electromechanical oscillation, flexible set-up of basic parameters of the oscillation cycle (negative strip time and its ratio. Proper oscillation mode is capable to assure regular oscillation marks development, good lubrication in the mould and adequate compression of the solidifying shell. Impact of an oscillation mode providing negative strip time 0.085 s and its ratio -50 % on surface quality of cast billets is compared with standard oscillation mode applied on strands equipped with electromechanical oscillation characterized with variable negative strip time between 0.084 and 0.096 s and fixed negative strip ratio to -14 %.

  17. Assessment of impact of strong earthquakes to the global economy by example of Thoku event

    Science.gov (United States)

    Tatiana, Skufina; Peter, Skuf'in; Sergey, Baranov; Vera, Samarina; Taisiya, Shatalova

    2016-04-01

    We examine the economic consequences of strong earthquakes by example of M9 Tahoku one that occurred on March 11, 2011 close to the northeast shore of Japanese coast Honshu. This earthquake became the strongest in the whole history of the seismological observations in this part of the planet. The generated tsunami killed more than 15,700 people, damaged 332,395 buildings and 2,126 roads. The total economic loss in Japan was estimated at 309 billion. The catastrophe in Japan also impacted global economy. To estimate its impact, we used regional and global stock indexes, production indexes, stock prices of the main Japanese, European and US companies, import and export dynamics, as well as the data provided by the custom of Japan. We also demonstrated that the catastrophe substantially affected the markets and on the short run in some indicators it even exceeded the effect of the global financial crisis of 2008. The last strong earthquake occurred in Nepal (25.04.2015, M7.8) and Chile (16.09.2015, M8.3), both actualized the research of cost assessments of the overall economic impact of seismic hazard. We concluded that it is necessary to treat strong earthquakes as one very important factor that affects the world economy depending on their location. The research was supported by Russian Foundation for Basic Research (Project 16-06-00056A).

  18. Impact of processing parameters on the LTCC channels geometry*

    Directory of Open Access Journals (Sweden)

    Macioszczyk Jan

    2015-12-01

    Full Text Available A great advantage of Low Temperature Co-fired Ceramics (LTCC yields the possibility of channel and air cavity fabrication. Such empty spaces have numerous applications, for example, in microfluidics, microwave techniques and integrated packaging. However, improper geometry of these structures can degrade the performance of the final device. The processing parameters recommended by the LTCC tape supplier are relevant for the production of multilayer circuits but not surface embedded channels and/or cavities. Thus, it is important to examine which factors of the fabrication process are the most significant. In our study, special attention has been paid to the geometric performance of the channel structure resulting from the applied processing parameters. Laser cutting parameters were checked to obtain the structures with great fidelity. The impact of an isostatic lamination on the quality of the final structure was analyzed. The influence of pressure and temperature of the lamination process on the channel geometry and tape shrinkage were examined. The performed experiments showed that some improvements in channel/cavity geometry may be achieved by optimizing the processing procedures. The microscopic observations combined with the Analysis of Variance (ANOVA showed which combinations of the processing parameters are the best for achieving a channel/cavity structure with the desired geometry.

  19. Effects of strong earthquakes in variations of electrical and meteorological parameters of the near-surface atmosphere in Kamchatka region

    Science.gov (United States)

    Smirnov, S. E.; Mikhailova, G. A.; Mikhailov, Yu. M.; Kapustina, O. V.

    2017-09-01

    The diurnal variations in electrical (quasistatic electric field and electrical conductivity) and meteorological (temperature, pressure, relative humidity of the atmosphere, and wind speed) parameters, measured simultaneously before strong earthquakes in Kamchatka region (November 15, 2006, M = 8.3; January 13, 2007, M = 8.1; January 30, 2016, M = 7.2), are studied for the first time in detail. It is found that a successively anomalous increase in temperature, despite the negative regular trend in these winter months, was observed in the period of six-seven days before the occurrences of earthquakes. An anomalous temperature increase led to the formation of "winter thunderstorm" conditions in the near-surface atmosphere of Kamchatka region, which was manifested in the appearance of an anomalous, type 2 electrical signal, the amplification of and intensive variations in electrical conductivity, heavy precipitation (snow showers), high relative humidity of air, storm winds, and pressure changes. With the weak flow of natural heat radiation in this season, the observed dynamics of electric and meteorological processes can likely be explained by the appearance of an additional heat source of seismic nature.

  20. Impact analysis of input parameter for damage detection code

    Directory of Open Access Journals (Sweden)

    Venglar Michal

    2017-01-01

    Full Text Available The primary aim of the article is to analyse impact of appropriate values of input parameter for an effective solution of the self-developed code used for damage detection. The code was prepared to determine the change of bending stiffness in Microsoft Office Excel Visual Basic for Applications. The code used non-destructive vibration based method, i.e. the FE model updating method. A steel bar was assumed for numerical calculation. Time consumption of calculation, precision of identification and degree of possible damage detection were investigated. The values of computation time depend on the input values, the desired limit of the accepted error. Then, data from a laboratory experiment was analysed. The damage detection was done in accordance with the suitable input data from a parametric study of the steel bar.

  1. Impact parameter trigger and vertex detector for forward collider

    International Nuclear Information System (INIS)

    Selove, W.

    1993-01-01

    In a forward collider design, Coulomb scattering produces an unavoidable smearing of the vertex region by low-p t tracks. A detector and triggering design is described which aims at differentiating B events from minimum bias events with high efficiency, in spite of this smearing, by measuring momentum and p t of all tracks in real time, and triggering only when an event shows a number of high-p t tracks with substantial impact parameters. Triggering efficiency an order of magnitude larger than for a lepton trigger can be anticipated. Detector planes are located within 4 millimeters of the beam line; a replaceable-vertex-region design provides for rapid replacement of radiation damaged closest elements at time intervals of a few months

  2. Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies

    DEFF Research Database (Denmark)

    Lal, Dennis; Ruppert, Ann-Kathrin; Trucks, Holger

    2015-01-01

    Genetic generalised epilepsy (GGE) is the most common form of genetic epilepsy, accounting for 20% of all epilepsies. Genomic copy number variations (CNVs) constitute important genetic risk factors of common GGE syndromes. In our present genome-wide burden analysis, large (≥ 400 kb) and rare (...%) autosomal microdeletions with high calling confidence (≥ 200 markers) were assessed by the Affymetrix SNP 6.0 array in European case-control cohorts of 1,366 GGE patients and 5,234 ancestry-matched controls. We aimed to: 1) assess the microdeletion burden in common GGE syndromes, 2) estimate the relative...... a strong impact of fundamental neurodevelopmental processes in the pathogenesis of common GGE syndromes....

  3. The Strong Wind event of 24th January 2009 in Catalonia: a social impact analysis

    Science.gov (United States)

    Amaro, J.; Aran, M.; Barberia, L.; Llasat, M. C.

    2009-09-01

    Although strong winds are frequent in Catalonia, one of the events with the strongest impact in recent years was on January 24th 2009. An explosive cyclogenesis process took place in the Atlantic: pressure fell 30 hPa in less than 24 hours. The strong wind storm pounded the northern of Spain and the south of France with some fatalities and important economic losses in these regions. Several automatic weather stations recorded wind gusts higher than 100 km/h in Catalonia. Emergency services received more than 20.000 calls in 24 hours and there were 497 interventions in only 12 hours. As a consequence of fallen and uprooted trees railway and road infrastructures got damages and more than 30.000 customers had no electricity during 24 hours. Unfortunately there were a total of 6 fatalities, two of them because of fallen trees and the other ones when a sports centre collapsed over a group of children. In Spain, insurance policies cover damages due to strong winds when fixed thresholds are overcome and, according to the Royal Decree 300/2004 of 20th February, extraordinary risk are assumed by the Consorcio de Compensación de Seguros. Subsequently, Public Weather Services (PWS) had an increased on the number of requests received from people affected by this event and from insurance companies, for the corresponding indemnity or not. As an example, during the first month after the event, in the Servei Meteorològic de Catalunya (SMC) more than 600 requests were received only related to these damages (as an average PWS of SMC received a total of 400 requests per month). Following the research started by the Social Impact Research Group of MEDEX project, a good vulnerability indicator of a meteorological risk can be the number of requests reported. This study uses the information received in the PWS of the SMC during the six months after the event, according the criteria and methodology established in Gayà et al (2008). The objective is to compare the vulnerability with the

  4. Sensitivity of Asteroid Impact Risk to Uncertainty in Asteroid Properties and Entry Parameters

    Science.gov (United States)

    Wheeler, Lorien; Mathias, Donovan; Dotson, Jessie L.; NASA Asteroid Threat Assessment Project

    2017-10-01

    A central challenge in assessing the threat posed by asteroids striking Earth is the large amount of uncertainty inherent throughout all aspects of the problem. Many asteroid properties are not well characterized and can range widely from strong, dense, monolithic irons to loosely bound, highly porous rubble piles. Even for an object of known properties, the specific entry velocity, angle, and impact location can swing the potential consequence from no damage to causing millions of casualties. Due to the extreme rarity of large asteroid strikes, there are also large uncertainties in how different types of asteroids will interact with the atmosphere during entry, how readily they may break up or ablate, and how much surface damage will be caused by the resulting airbursts or impacts.In this work, we use our Probabilistic Asteroid Impact Risk (PAIR) model to investigate the sensitivity of asteroid impact damage to uncertainties in key asteroid properties, entry parameters, or modeling assumptions. The PAIR model combines physics-based analytic models of asteroid entry and damage in a probabilistic Monte Carlo framework to assess the risk posed by a wide range of potential impacts. The model samples from uncertainty distributions of asteroid properties and entry parameters to generate millions of specific impact cases, and models the atmospheric entry and damage for each case, including blast overpressure, thermal radiation, tsunami inundation, and global effects. To assess the risk sensitivity, we alternately fix and vary the different input parameters and compare the effect on the resulting range of damage produced. The goal of these studies is to help guide future efforts in asteroid characterization and model refinement by determining which properties most significantly affect the potential risk.

  5. Discrete element modelling (DEM) input parameters: understanding their impact on model predictions using statistical analysis

    Science.gov (United States)

    Yan, Z.; Wilkinson, S. K.; Stitt, E. H.; Marigo, M.

    2015-09-01

    Selection or calibration of particle property input parameters is one of the key problematic aspects for the implementation of the discrete element method (DEM). In the current study, a parametric multi-level sensitivity method is employed to understand the impact of the DEM input particle properties on the bulk responses for a given simple system: discharge of particles from a flat bottom cylindrical container onto a plate. In this case study, particle properties, such as Young's modulus, friction parameters and coefficient of restitution were systematically changed in order to assess their effect on material repose angles and particle flow rate (FR). It was shown that inter-particle static friction plays a primary role in determining both final angle of repose and FR, followed by the role of inter-particle rolling friction coefficient. The particle restitution coefficient and Young's modulus were found to have insignificant impacts and were strongly cross correlated. The proposed approach provides a systematic method that can be used to show the importance of specific DEM input parameters for a given system and then potentially facilitates their selection or calibration. It is concluded that shortening the process for input parameters selection and calibration can help in the implementation of DEM.

  6. In Vitro Fertilization and Embryo Culture Strongly Impact the Placental Transcriptome in the Mouse Model

    Science.gov (United States)

    Fauque, Patricia; Mondon, Françoise; Letourneur, Franck; Ripoche, Marie-Anne; Journot, Laurent; Barbaux, Sandrine; Dandolo, Luisa; Patrat, Catherine; Wolf, Jean-Philippe; Jouannet, Pierre; Jammes, Hélène; Vaiman, Daniel

    2010-01-01

    Background Assisted Reproductive Technologies (ART) are increasingly used in humans; however, their impact is now questioned. At blastocyst stage, the trophectoderm is directly in contact with an artificial medium environment, which can impact placental development. This study was designed to carry out an in-depth analysis of the placental transcriptome after ART in mice. Methodology/Principal Findings Blastocysts were transferred either (1) after in vivo fertilization and development (control group) or (2) after in vitro fertilization and embryo culture. Placentas were then analyzed at E10.5. Six percent of transcripts were altered at the two-fold threshold in placentas of manipulated embryos, 2/3 of transcripts being down-regulated. Strikingly, the X-chromosome harbors 11% of altered genes, 2/3 being induced. Imprinted genes were modified similarly to the X. Promoter composition analysis indicates that FOXA transcription factors may be involved in the transcriptional deregulations. Conclusions For the first time, our study shows that in vitro fertilization associated with embryo culture strongly modify the placental expression profile, long after embryo manipulations, meaning that the stress of artificial environment is memorized after implantation. Expression of X and imprinted genes is also greatly modulated probably to adapt to adverse conditions. Our results highlight the importance of studying human placentas from ART. PMID:20169163

  7. In vitro fertilization and embryo culture strongly impact the placental transcriptome in the mouse model.

    Directory of Open Access Journals (Sweden)

    Patricia Fauque

    Full Text Available BACKGROUND: Assisted Reproductive Technologies (ART are increasingly used in humans; however, their impact is now questioned. At blastocyst stage, the trophectoderm is directly in contact with an artificial medium environment, which can impact placental development. This study was designed to carry out an in-depth analysis of the placental transcriptome after ART in mice. METHODOLOGY/PRINCIPAL FINDINGS: Blastocysts were transferred either (1 after in vivo fertilization and development (control group or (2 after in vitro fertilization and embryo culture. Placentas were then analyzed at E10.5. Six percent of transcripts were altered at the two-fold threshold in placentas of manipulated embryos, 2/3 of transcripts being down-regulated. Strikingly, the X-chromosome harbors 11% of altered genes, 2/3 being induced. Imprinted genes were modified similarly to the X. Promoter composition analysis indicates that FOXA transcription factors may be involved in the transcriptional deregulations. CONCLUSIONS: For the first time, our study shows that in vitro fertilization associated with embryo culture strongly modify the placental expression profile, long after embryo manipulations, meaning that the stress of artificial environment is memorized after implantation. Expression of X and imprinted genes is also greatly modulated probably to adapt to adverse conditions. Our results highlight the importance of studying human placentas from ART.

  8. Identification of Operating Parameters Most Strongly Influencing the Jetting Performance in a Piezoelectric Actuator-Driven Dispenser

    Directory of Open Access Journals (Sweden)

    Jung Woo Sohn

    2018-02-01

    Full Text Available This work identifies crucial operating parameters which most significantly influence the jetting performances of piezostack-driven non-contact dispensers. This is achieved through experimental investigation and statistical analysis. After introducing the configuration and operating principle of the piezoelectric jetting dispenser, an experimental setup is constructed in order to test the jetting performance, such as the dispensed amount. After selecting four significant operating parameters for the light-emitting diode (LED-packaging process, two levels for each parameter are considered. Subsequently, the weight of a single dispensed dot is measured 100 times, and the average weight and standard deviation are calculated for each experimental set. The results are then statistically analyzed using a commercial software package. Finally, the crucial operating parameters which provide a low average weight and a minimum variation in the weight of a single dispensed dot are identified.

  9. The strong prognostic value of KELIM, a model-based parameter from CA 125 kinetics in ovarian cancer

    DEFF Research Database (Denmark)

    You, Benoit; Colomban, Olivier; Heywood, Mark

    2013-01-01

    Unexpected results were recently reported about the poor surrogacy of Gynecologic Cancer Intergroup (GCIG) defined CA-125 response in recurrent ovarian cancer (ROC) patients. Mathematical modeling may help describe CA-125 decline dynamically and discriminate prognostic kinetic parameters....

  10. THE IMPACT OF COMORBIDITY ON COGNITIVE PARAMETERS AFTER ISCHEMIC STROKE

    Directory of Open Access Journals (Sweden)

    Mirena Valkova

    2012-10-01

    Full Text Available Objective: The aim of our study is to examine the impact of comorbidity on cognitive parameters after the first ever ischemic stroke.Material and methods: We examined 112 patients (aged 46 to 84 (66.67± 5.96, 69 males and 43 females with first ever ischemic stroke. For cognitive assessment we used Mini Mental State Examination (MMSE, 10 word test (for short term memory and delayed recall, Isaack’s test for verbal fluency (VF, Geriatric depression scale (GDS, Hamilton depression scale (HDS, Blessed dementia information memory concentration test (revised, BDIMCT, Benton Visual Retention test (A,E; BVRT – number of corrects and number of errors and Wiskonsin Card Sorting Test (number of errors, WCST. The patients were examined on two step model. At acute stage, after collecting medical history, somatic and neurological examinations, MMSE, 10 words test and HDS were applied. At subacute stroke stage (90±5 days after first stroke symptoms, all cognitive tests were used. „STATGRAPHICS Plus 5.0 (free version” was used for statistical analysis.Results: Chronic ischemic heart disease and chronic obstructive pulmonary disease are the most important additional risk factors for cognitive decline. Thyroid pathology, renal failure and anemia are independently associated with poststroke depression.Conclusions: On the basis of these data we can conclude that vascular risk factors are independently associated with cognitive and emotional changes after stroke and their effects should be assessed and taken into account for subsequent treatment of stroke survivors.

  11. Overview of the relations earthquake source parameters and the specification of strong ground motion for design purposes

    International Nuclear Information System (INIS)

    Bernreuter, D.L.

    1977-08-01

    One of the most important steps in the seismic design process is the specification of the appropriate ground motion to be input into the design analysis. From the point-of-view of engineering design analysis, the important parameters are peak ground acceleration, spectral shape and peak spectral levels. In a few cases, ground displacement is a useful parameter. The earthquake is usually specified by giving its magnitude and either the epicentral distance or the distance of the closest point on the causitive fault to the site. Typically, the appropriate ground motion parameters are obtained using the specified magnitude and distance in equations obtained from regression analysis among the appropriate variables. Two major difficulties with such an approach are: magnitude is not the best parameter to use to define the strength of an earthquake, and little near-field data is available to establish the appropriate form for the attenuation of the ground motion with distance, source size and strength. These difficulties are important for designing a critical facility; i.e., one for which a very low risk of exceeding the design ground motion is required. Examples of such structures are nuclear power plants, schools and hospitals. for such facilities, a better understanding of the relation between the ground motion and the important earthquake source parameters could be very useful for several reasons

  12. Calculation of the zero-field splitting D and g(perp)parameters in EPR for d3 spin systems in strong and moderate axial fields

    NARCIS (Netherlands)

    Kool, Th.W.; Bollegraaf, B.

    2010-01-01

    Numerical and analytical methods are used to investigate the calculation of the zero field splitting |2D| and g(perp) parameters in EPR for octahedrally surrounded d3 spin systems (S = 3/2) in strong and moderate axial crystal fields (|D|>=h{\

  13. Influence of inherent parameter of stabilized UHF oscillators on autodyne response formation at a strong reflected signal

    Directory of Open Access Journals (Sweden)

    Noskov V. Ya.

    2011-08-01

    Full Text Available Results of an autodyne response analysis in UHF oscillators stabilized by the external high-Q cavity in the case of the strong signal when the reflected wave amplitude commen-surable with the own oscillation amplitude. Coupling between the basic operation cavity and the stabilizing cavity is implemented as a pass-reflecting filter with a resistive bond. Key relations are obtained, which describe the autodyne response to the own re-reflected radiation from a target. The load and oscillating system influence on autodyne response formation is fulfilled.

  14. Strong synergistic effects in PLA/PCL blends: Impact of PLA matrix viscosity.

    Science.gov (United States)

    Ostafinska, Aleksandra; Fortelný, Ivan; Hodan, Jiří; Krejčíková, Sabina; Nevoralová, Martina; Kredatusová, Jana; Kruliš, Zdeněk; Kotek, Jiří; Šlouf, Miroslav

    2017-05-01

    Blends of two biodegradable polymers, poly(lactic acid) (PLA) and poly(ϵ-caprolactone) (PCL), with strong synergistic improvement in mechanical performance were prepared by melt-mixing using the optimized composition (80/20) and the optimized preparation procedure (a melt-mixing followed by a compression molding) according to our previous study. Three different PLA polymers were employed, whose viscosity decreased in the following order: PLC ≈ PLA1 > PLA2 > PLA3. The blends with the highest viscosity matrix (PLA1/PCL) exhibited the smallest PCL particles (d∼0.6μm), an elastic-plastic stable fracture (as determined from instrumented impact testing) and the strongest synergistic improvement in toughness (>16× with respect to pure PLA, exceeding even the toughness of pure PCL). According to the available literature, this was the highest toughness improvement in non-compatiblized PLA/PCL blends ever achieved. The decrease in the matrix viscosity resulted in an increase in the average PCL particle size and a dramatic decrease in the overall toughness: the completely stable fracture (for PLA1/PCL) changed to the stable fracture followed by unstable crack propagation (for PLA2/PCL) and finally to the completely brittle fracture (for PLA3/PCL). The stiffness of all blends remained at well acceptable level, slightly above the theoretical predictions based on the equivalent box model. Despite several previous studies, the results confirmed that PLA and PCL could behave as compatible polymers, but the final PLA/PCL toughness is extremely sensitive to the PCL particle size distribution, which is influenced by both processing conditions and PLA viscosity. PLA/PCL blends with high stiffness (due to PLA) and toughness (due to PCL) are very promising materials for medical applications, namely for the bone tissue engineering. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Laser and Plasma Parameters for Laser Pulse Amplification by Stimulated Brillouin Backscattering in the Strong Coupling Regime

    Science.gov (United States)

    Gangolf, Thomas; Blecher, Marius; Bolanos, Simon; Lancia, Livia; Marques, Jean-Raphael; Cerchez, Mirela; Prasad, Rajendra; Aurand, Bastian; Loiseau, Pascal; Fuchs, Julien; Willi, Oswald

    2017-10-01

    In the ongoing quest for novel techniques to obtain ever higher laser powers, plasma amplification has drawn much attention, benefiting from the fact that a plasma can sustain much higher energy densities than a solid state amplifier. As a plasma process, Stimulated Brillouin Backscattering in the strong coupling regime (sc-SBS) can be used to transfer energy from one laser pulse (pump) to another (seed), by a nonlinear ion oscillation forced by the pump laser. Here, we report on experimental results on amplification by sc-SBS using the ARCTURUS Ti:Sapphire multi-beam laser system at the University of Duesseldorf, Germany. Counter-propagating in a supersonic Hydrogen gas jet target, an ultrashort seed pulse with a pulse duration between 30 and 160 fs and an energy between 1 and 12 mJ was amplified by a high-energy pump pulse (1.7 ps, 700 mJ). For some of the measurements, the gas was pre-ionized with a separate laser pulse (780 fs, 460 mJ). Preliminary analysis shows that the amplification was larger for the longer seed pulses, consistent with theoretical predictions.

  16. Impact of strong climate change on balancing and storage needs in a fully renewable energy system

    Science.gov (United States)

    Weber, Juliane; Wohland, Jan; Witthaut, Dirk

    2017-04-01

    We investigate the impact of strong climate change on a European energy system dominated by wind power. No robust trend can be observed regarding the change of the wind power yield for most countries in Europe. However, intra-annual variabilities in wind power generation robustly increase in most of Central and Western Europe and decrease in Spain, Portugal and Greece by the end of this century. Thus, the generation of wind power tends to increase (decrease) in the winter months compared to the summer months. Due to higher (lower) intra-annual variations, the probability for extreme events with long periods of low power production increases (decreases) in summer. This implies that more (less) energy has to be provided by backup power plants. Our simulations are based on the results of five different Global Climate Models (GCMs) using the Representative Concentration Pathway scenario 8.5 (RCP8.5). These results are dynamically downscaled with the regional atmospheric model RCA4 by the EURO-CORDEX initiative (Coordinated Downscaling Experiment - European Domain). A comparison was made between historical data (1970-2000) and mid-century (2030-2060) and end-of-century (2070-2100) data, respectively. For all timeframes we made the assumption that a certain amount of energy is provided by wind power plants. This implies that changes in wind power potentials are neglected and only temporal effects are considered. Wind speed time series are converted to power generation time series using an extrapolation to hub height and a standardized power curve. Assuming a scenario for the future distribution of wind turbines, we obtain a wind power generation time series aggregated on a national level. The operation of backup power plants and storage facilities is simulated on coarse scales assuming an optimal storage strategy. Backup is required whenever the storage facilities are empty. The amount of change of the backup energy depends on the storage capacity - the higher the

  17. CMB Beam Systematics: Impact on Lensing Parameter Estimation

    OpenAIRE

    Miller, N. J.; Shimon, M.; Keating, B. G.

    2008-01-01

    The CMB's B-mode polarization provides a handle on several cosmological parameters most notably the tensor-to-scalar ratio, $r$, and is sensitive to parameters which govern the growth of large scale structure (LSS) and evolution of the gravitational potential. The primordial gravitational-wave- and secondary lensing-induced B-mode signals are very weak and therefore prone to various foregrounds and systematics. In this work we use Fisher-matrix-based estimations and apply, for the first time,...

  18. Impact of relativistic effects on cosmological parameter estimation

    Science.gov (United States)

    Lorenz, Christiane S.; Alonso, David; Ferreira, Pedro G.

    2018-01-01

    Future surveys will access large volumes of space and hence very long wavelength fluctuations of the matter density and gravitational field. It has been argued that the set of secondary effects that affect the galaxy distribution, relativistic in nature, will bring new, complementary cosmological constraints. We study this claim in detail by focusing on a subset of wide-area future surveys: Stage-4 cosmic microwave background experiments and photometric redshift surveys. In particular, we look at the magnification lensing contribution to galaxy clustering and general-relativistic corrections to all observables. We quantify the amount of information encoded in these effects in terms of the tightening of the final cosmological constraints as well as the potential bias in inferred parameters associated with neglecting them. We do so for a wide range of cosmological parameters, covering neutrino masses, standard dark-energy parametrizations and scalar-tensor gravity theories. Our results show that, while the effect of lensing magnification to number counts does not contain a significant amount of information when galaxy clustering is combined with cosmic shear measurements, this contribution does play a significant role in biasing estimates on a host of parameter families if unaccounted for. Since the amplitude of the magnification term is controlled by the slope of the source number counts with apparent magnitude, s (z ), we also estimate the accuracy to which this quantity must be known to avoid systematic parameter biases, finding that future surveys will need to determine s (z ) to the ˜5 %- 10 % level. On the contrary, large-scale general-relativistic corrections are irrelevant both in terms of information content and parameter bias for most cosmological parameters but significant for the level of primordial non-Gaussianity.

  19. Impact of Parameter Variations on Multi-Core Chips

    National Research Council Canada - National Science Library

    Humenay, Eric; Tarjan, David; Skadron, Kevin

    2006-01-01

    ...s. This paper introduces a pre-RTL, architectural modeling methodology that incorporates the impact of manufacturing and runtime temperature variations on delay and power for both combinational logic and SRAM structures...

  20. impact of some climatic and phenological parameters on the ...

    African Journals Online (AJOL)

    Prof. Adipala Ekwamu

    climatic and phenological parameters explain 52.80% callogenesis variations, against 31.50% for SE. Therefore, climate and phenology significantly influence callogenesis, but not SE. For further industrial production of secondary metabolites such as butter, theobromin and chocolate aroma from calli, it would be desirable ...

  1. The impact of various assessment parameters on medical students ...

    African Journals Online (AJOL)

    Materials and Methods: The results of all 244 students that sat for the examination over 4 years were used. The CA, MCQ, essay, practical, oral and overall performance scores were obtained. All the scores were rounded up to 100% to give each parameter equal weighting. Results: Analysis showed that the average overall ...

  2. Impact of some climatic and phenological parameters on the ...

    African Journals Online (AJOL)

    In the first year, in control clones,climatic and phenological parameters explain 52.80% callogenesis variations, against 31.50% for SE. Therefore,climate and phenology significantly influence callogenesis, but not SE. For further industrial production of secondary metabolites such as butter, the obromin and chocolate aroma ...

  3. Impact of nickel (Ni) on hematological parameters and behavioral ...

    African Journals Online (AJOL)

    Jane

    2011-10-17

    Oct 17, 2011 ... copper on blood and biochemical parameters of rainbow trout. (Oncorhynchus mykiss). Arch. Environ. Contamin. Toxicol. 36: 415-. 423. Dickman MD, Leung KM (1998). Mercury and organo chlorine exposure from fish consumption in Hong Kong. Chemosphere, 37: 991-1015. Eisler R, Gardener GR (1973).

  4. Strong impact of lattice vibrations on electronic and magnetic properties of paramagnetic Fe revealed by disordered local moments molecular dynamics

    NARCIS (Netherlands)

    Alling, B.; Kormann, F.H.W.; Grabowski, B; Glensk, A; Abrikosov, I.A.

    2016-01-01

    We study the impact of lattice vibrations on magnetic and electronic properties of paramagnetic bcc and fcc iron at finite temperature, employing the disordered local moments molecular dynamics (DLM-MD) method. Vibrations strongly affect the distribution of local magnetic moments at finite

  5. Impact of certain corn cultivars on some ological parameters of ...

    African Journals Online (AJOL)

    The development, survival rate, reproduction and biological parameters of the corn leaf aphid, Rhopalosiphum maidis (Fitch), on five corn cultivars were evaluated at 25°C under laboratory conditions. The corn leaf aphid had a longer nymphal developmental time of 4.99, 4.98, 4.73, 4.46, and 5.60 day of Ada9516, K. Arifiye, ...

  6. Knitted strain sensors: impact of design parameters on sensing properties.

    Science.gov (United States)

    Atalay, Ozgur; Kennon, William Richard

    2014-03-07

    This paper presents a study of the sensing properties exhibited by textile-based knitted strain sensors. Knitted sensors were manufactured using flat-bed knitting technology, and electro-mechanical tests were subsequently performed on the specimens using a tensile testing machine to apply strain whilst the sensor was incorporated into a Wheatstone bridge arrangement to allow electrical monitoring. The sensing fabrics were manufactured from silver-plated nylon and elastomeric yarns. The component yarns offered similar diameters, bending characteristics and surface friction, but their production parameters differed in respect of the required yarn input tension, the number of conductive courses in the sensing structure and the elastomeric yarn extension characteristics. Experimental results showed that these manufacturing controls significantly affected the sensing properties of the knitted structures such that the gauge factor values, the working range and the linearity of the sensors varied according to the knitted structure. These results confirm that production parameters play a fundamental role in determining the physical behavior and the sensing properties of knitted sensors. It is thus possible to manipulate the sensing properties of knitted sensors and the sensor response may be engineered by varying the production parameters applied to specific designs.

  7. Knitted Strain Sensors: Impact of Design Parameters on Sensing Properties

    Directory of Open Access Journals (Sweden)

    Ozgur Atalay

    2014-03-01

    Full Text Available This paper presents a study of the sensing properties exhibited by textile-based knitted strain sensors. Knitted sensors were manufactured using flat-bed knitting technology, and electro-mechanical tests were subsequently performed on the specimens using a tensile testing machine to apply strain whilst the sensor was incorporated into a Wheatstone bridge arrangement to allow electrical monitoring. The sensing fabrics were manufactured from silver-plated nylon and elastomeric yarns. The component yarns offered similar diameters, bending characteristics and surface friction, but their production parameters differed in respect of the required yarn input tension, the number of conductive courses in the sensing structure and the elastomeric yarn extension characteristics. Experimental results showed that these manufacturing controls significantly affected the sensing properties of the knitted structures such that the gauge factor values, the working range and the linearity of the sensors varied according to the knitted structure. These results confirm that production parameters play a fundamental role in determining the physical behavior and the sensing properties of knitted sensors. It is thus possible to manipulate the sensing properties of knitted sensors and the sensor response may be engineered by varying the production parameters applied to specific designs.

  8. The evaluation of the state of environment under a strong human impact on the basis of SWOT analysis

    Science.gov (United States)

    Dråg, Magdalena; Zimnol, Jan

    2014-10-01

    Environmental assessment of areas subject to strong human pressure is a growing problem worldwide. This is true also for Poland The Upper Silesian conurbation, which is dominated by heavy industry: steel mills, mining, chemical industry, as well as power plants and thermal power plants. The assessment analyses catchment Kłodnica in which anthropogenic impacts are very strong and long lasting. In order to assess the current state of the environment, a cartogram was established in which both factors, positively and negatively affecting the environment of the analysed area are reflected. To create a results-cartogram, SWOT analysis was used.

  9. Impact of Solar wind plasma parameters on geomagnetic condition

    Science.gov (United States)

    Rathore, Balveer Singh; Gupta, Dinesh Chandra

    Today’s challenge for space weather research is to quantitatively predict the dynamics of the magnetosphere from measured solar wind and interplanetary magnetic field conditions. A correlative studies between the Geomagnetic Storms (GMSs) and the various interplanetary field/plasma parameters have been performed to search the causes of geomagnetic activity and developing models for prediction of the occurrence of GMSs which are important for space weather predictions. In the present paper we found possible co-relation of geomagnetic storms with solar wind and IMF parameters in three different situations and also drive the linear relation equation for all parameters in three situations. On basis of present statistical study we developed an empirical model. With the help of this model we can predict all categories of geomagnetic storms. This model based on following fact. The total interplanetary magnetic field Btotal can use as alarm of geomagnetic storms, when sudden changes in total magnetic field B total, it is a first alarm on condition for storms arrival. It is observed in the present study that southward Bz-component of IMF is an important factor for geomagnetic storms. And it is the result of the paper that the magnitude of Bz is maximum neither during initial phase (at the instant of IP shock) nor during main phase (at the instant of Dst minimum). So it is seen in this study that there is a time delay between maximum value of southward Bz and Dst minimum and this time delay can be used in the prediction of the intensity of magnetic storm two -three hours before of main phase of geomagnetic storm. A linear relation have been derived between maximum value of southward component of Bz and Dst for prediction is Dst = (-0.06) + (7.65)Bz + t. Some auxiliary condition should be fulfils with this, speed of solar wind should be on average 350 km/s to 750 km/s, plasma beta should be low and most important plasma temperature should be low for intense storms if plasma

  10. Impact parameter and energy dependence of the dynamics of nucleus-nucleus collisions below 100 MeV/u

    International Nuclear Information System (INIS)

    Peter, J.

    1990-10-01

    The multidetector array Mur + Tonneau has been used to perform a 4π detection of charged particles and fragments emitted in reactions between 40 Ar, at energies ranging from 25 to 85 MeV/u, and 27 Al or 58 Ni target. The events have been sorted as a function of the impact parameter value, using a new global variable, the average parallel velocity. The pre-equilibrium emission from the interaction region increases strongly when the incident energy increases and when the impact parameter decreases. It severely limits the mass and excitation energy of the equilibrated partial fusion nuclei, even in central collisions. The collective transverse momentum in the reaction plane (flow) is observed to strongly vary as a function of impact parameter and incident energy. Its value falls to zero in the range 70-80 MeV/u for central collisions. These results are compared to predictions based on the Landau-Vlasov and Boltzmann equations in order, to get information on the nucleon-nucleon cross section in medium and the equation of state of nuclear matter. 8 figs

  11. Strong synergistic effects in PLA/PCL blends: impact of PLA matrix viscosity

    Czech Academy of Sciences Publication Activity Database

    Ostafinska, Aleksandra; Fortelný, Ivan; Hodan, Jiří; Krejčíková, Sabina; Nevoralová, Martina; Kredatusová, Jana; Kruliš, Zdeněk; Kotek, Jiří; Šlouf, Miroslav

    2017-01-01

    Roč. 69, May (2017), s. 229-241 ISSN 1751-6161 R&D Projects: GA ČR(CZ) GA14-17921S; GA MŠk(CZ) LO1507 Institutional support: RVO:61389013 Keywords : polymer blends * bone tissue engineering * poly(lactic acid) Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 3.110, year: 2016

  12. Impact of strong geomagnetic storms on total ozone at southern higher middle latitudes

    Czech Academy of Sciences Publication Activity Database

    Laštovička, Jan; Križan, Peter

    2009-01-01

    Roč. 53, č. 1 (2009), s. 151-156 ISSN 0039-3169 R&D Projects: GA MŠk 1P05OC030 Grant - others:European Commission(XE) COST 724 Institutional research plan: CEZ:AV0Z30420517 Keywords : ozone * Southern Hemisphere * geomagnetic storms * Forbush decreases of cosmic rays Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 1.000, year: 2009

  13. Impact of the strong electromagnetic field on the QCD effective potential for homogeneous Abelian gluon field configurations

    International Nuclear Information System (INIS)

    Galilo, Bogdan V.; Nedelko, Sergei N.

    2011-01-01

    The one-loop quark contribution to the QCD effective potential for the homogeneous Abelian gluon field in the presence of an external strong electromagnetic field is evaluated. The structure of extrema of the potential as a function of the angles between chromoelectric, chromomagnetic, and electromagnetic fields is analyzed. In this setup, the electromagnetic field is considered as an external one while the gluon field represents domain structured nonperturbative gluon configurations related to the QCD vacuum in the confinement phase. Two particularly interesting gluon configurations, (anti-)self-dual and crossed orthogonal chromomagnetic and chromoelectric fields, are discussed specifically. Within this simplified framework it is shown that the strong electromagnetic fields can play a catalyzing role for a deconfinement transition. At the qualitative level, the present consideration can be seen as a highly simplified study of an impact of the electromagnetic fields generated in relativistic heavy ion collisions on the strongly interacting hadronic matter.

  14. Impact of cell phone use on men's semen parameters.

    Science.gov (United States)

    Gutschi, T; Mohamad Al-Ali, B; Shamloul, R; Pummer, K; Trummer, H

    2011-10-01

    The objective of the present retrospective study was to report our experience concerning the effects of cell phone usage on semen parameters. We examined 2110 men attending our infertility clinic from 1993 to October 2007. Semen analysis was performed in all patients. Serum free testosterone (T), follicle stimulating hormone (FSH), luteinising hormone (LH) and prolactin (PRL) were collected from all patients. The information on cell phone use of the patients was recorded and the subjects were divided into two groups according to their cell phone use: group A: cell phone use (n = 991); group B: no use (n = 1119). Significant difference was observed in sperm morphology between the two groups. In the patients of group A, 68.0% of the spermatozoa featured a pathological morphology compared to only 58.1% in the subjects of group B. Patients with cell phone usage showed significantly higher T and lower LH levels than those who did not use cell phone. No significant difference between the two groups was observed regarding FSH and PRL values. Our results showed that cell phone use negatively affects sperm quality in men. Further studies with a careful design are needed to determine the effect of cell phone use on male fertility. © 2011 Blackwell Verlag GmbH.

  15. Impact of ironman triathlon on oxidative stress Parameters

    Directory of Open Access Journals (Sweden)

    José Claudio Fonseca Moreira

    2012-03-01

    Full Text Available Several studies have investigated the biochemical response changes that take place in Ironman triathletes, but there are few data on oxidative stress changes. The objective of this study was to investigate oxidative stress parameters in triathletes after an Ironman event. The sample consisted of eighteen male triathletes, with a mean age of 34.5 ± 2.15 years, weight 69.3 ± 1.9 kg, and height 1.71 ± 0.18 m. The Ironman triathlon consists of a 3.8-km swim, a 180-km bicycle ride, and a 42.2-km (marathon run. Before the competition and immediately after its conclusion, 10-mL blood samples were collected, centrifuged and frozen at -80ºC for subsequent analysis. Total antioxidant capacity, lipid peroxidation, protein carbonylation, and total thiol content were measured. The results showed a significant increase in all markers after the event (p<0.05 in relation to the pre-event period, which conclusively shows that the Ironman triathlon induces significant changes oxidative stress markers in athletes and that antioxidant supplementation would be important to reverse these effects.

  16. Impact parameter dependence of π0 production in heavy ion collisions at subthreshold energies

    International Nuclear Information System (INIS)

    Badala, A.; Palmeri, A.; Pappalardo, G.S.; Russo, A.C.; Barbera, R.; Riggi, F.; Turrisi, R.; Bellia, G.; Migneco, E.; Peghaire, A.

    1994-01-01

    Previous experiences could not estimate quantitatively the impact parameter scale for the pion production, due to incomplete coverage of the total solid angle by detectors. The experiment presented here was carried with the multidetector MEDEA coupled to a forward hodoscope, with the aim to get such a quantitative estimate. The charged particle multiplicity was used in the present analysis as a global variable to extract the impact parameter scale within the modified fireball model. We established that pion production gives all the more useful information on the process dynamics that collisions can be classified according to their impact parameter. (D.L.). 14 refs., 4 figs

  17. Impact parameter dependence of {pi}{sup 0} production in heavy ion collisions at subthreshold energies

    Energy Technology Data Exchange (ETDEWEB)

    Badala, A.; Palmeri, A.; Pappalardo, G.S.; Russo, A.C. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Barbera, R.; Riggi, F.; Turrisi, R. [Istituto Nazionale di Fisica Nucleare, Catania (Italy)]|[Catania Univ. (Italy). Ist. di Fisica; Russo, G. [Catania Univ. (Italy). Ist. di Fisica; Agodi, C.; Alba, R.; Coniglione, R.; Del Zoppo, A.; Finocchiaro, P.; Maiolino, C.; Piattelli, P.; Sapienza, P. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Bellia, G.; Migneco, E. [Catania Univ. (Italy). Ist. di Fisica]|[Istituto Nazionale di Fisica Nucleare, Catania (Italy); Peghaire, A. [Grand Accelerateur National d`Ions Lourds (GANIL), 14 - Caen (France)

    1994-04-01

    Previous experiences could not estimate quantitatively the impact parameter scale for the pion production, due to incomplete coverage of the total solid angle by detectors. The experiment presented here was carried with the multidetector MEDEA coupled to a forward hodoscope, with the aim to get such a quantitative estimate. The charged particle multiplicity was used in the present analysis as a global variable to extract the impact parameter scale within the modified fireball model. We established that pion production gives all the more useful information on the process dynamics that collisions can be classified according to their impact parameter. (D.L.). 14 refs., 4 figs.

  18. The Impact of KIR Polymorphism on the Risk of Developing Cancer: Not as Strong as Imagined?

    Science.gov (United States)

    Augusto, Danillo G.

    2016-01-01

    The polymorphism of killer cell immunoglobulin-like receptors (KIR) has been associated with several diseases, including infection, autoimmunity and cancer. KIR molecules are a family of receptors expressed on the surface of natural killer cells (NK), frontline defense of innate immunity against microorganisms and neoplastic cells. Some studies have shown conflicting results concerning the role that KIR polymorphism plays in tumor susceptibility, particularly in leukemia and lymphoma. Interestingly, the presence of HLA ligands is sometimes strongly associated with several types of cancer and apparently is not related with their interaction with KIR. This manuscript briefly reviews the uncommon polymorphism of KIR and critically summarizes the recent findings with regards of the importance of KIR variation for cancer susceptibility. PMID:27446203

  19. Parameter uncertainty in CGE Modeling of the environmental impacts of economic policies

    Energy Technology Data Exchange (ETDEWEB)

    Abler, D.G.; Shortle, J.S. [Agricultural Economics, Pennsylvania State University, University Park, PA (United States); Rodriguez, A.G. [University of Costa Rica, San Jose (Costa Rica)

    1999-07-01

    This study explores the role of parameter uncertainty in Computable General Equilibrium (CGE) modeling of the environmental impacts of macroeconomic and sectoral policies, using Costa Rica as a case for study. A CGE model is constructed which includes eight environmental indicators covering deforestation, pesticides, overfishing, hazardous wastes, inorganic wastes, organic wastes, greenhouse gases, and air pollution. The parameters are treated as random variables drawn from prespecified distributions. Evaluation of each policy option consists of a Monte Carlo experiment. The impacts of the policy options on the environmental indicators are relatively robust to different parameter values, in spite of the wide range of parameter values employed. 33 refs.

  20. Parameter uncertainty in CGE Modeling of the environmental impacts of economic policies

    International Nuclear Information System (INIS)

    Abler, D.G.; Shortle, J.S.; Rodriguez, A.G.

    1999-01-01

    This study explores the role of parameter uncertainty in Computable General Equilibrium (CGE) modeling of the environmental impacts of macroeconomic and sectoral policies, using Costa Rica as a case for study. A CGE model is constructed which includes eight environmental indicators covering deforestation, pesticides, overfishing, hazardous wastes, inorganic wastes, organic wastes, greenhouse gases, and air pollution. The parameters are treated as random variables drawn from prespecified distributions. Evaluation of each policy option consists of a Monte Carlo experiment. The impacts of the policy options on the environmental indicators are relatively robust to different parameter values, in spite of the wide range of parameter values employed. 33 refs

  1. Oenological prefermentation practices strongly impact yeast population dynamics and alcoholic fermentation kinetics in Chardonnay grape must.

    Science.gov (United States)

    Albertin, Warren; Miot-Sertier, Cécile; Bely, Marina; Marullo, Philippe; Coulon, Joana; Moine, Virginie; Colonna-Ceccaldi, Benoit; Masneuf-Pomarede, Isabelle

    2014-05-16

    Yeast species of Hanseniaspora and Candida genus are predominant during the early stages of winemaking, while species of Metschnikowia, Pichia, Zygoascus, Issatchenkia, Torulaspora and other genera are present at lower population levels. The impact of common oenological practices on yeast dynamics during the prefermentative stage and the early stage of alcoholic fermentation (AF) remains elusive. In this work, the effect of four prefermentative oenological practices (clarification degree, temperature, sulphite and starter yeast addition) on yeast dynamics was evaluated in a Chardonnay grape must. The growth curves of four genus or species, namely Saccharomyces spp., Hanseniaspora spp., Candida zemplinina and Torulaspora delbrueckii, were followed by quantitative PCR. The fermentation kinetics were also recorded, as well as the production of acetic acid. Variance analysis allowed determining the effect of each practice and their interaction factors, as well as their relative importance on yeast dynamics and fermentation kinetics. Our experimental design showed that the population dynamics of the four species were differently impacted by the oenological practices, with some species being more sensitive than others to the clarification degree (C. zemplinina), sulphite addition (Saccharomyces spp.), starter yeast inoculation (Hanseniaspora spp.) or prefermentation temperature (T. delbrueckii). Significant interaction effects between practices were revealed, highlighting the interest of experimental design allowing interaction analysis, as some factors may buffer the effect of other ones. Hanseniaspora genus showed atypical behaviour: growth dynamics showed a decrease during AF that we interpreted as early cellular lysis. In conclusion, this study provides new insights on the impact of common oenological practices on the dynamics of non-Saccharomyces yeast that will be useful for a better management of mixed fermentation between S. cerevisiae and non

  2. Concert halls with strong and lateral sound increase the emotional impact of orchestra music.

    Science.gov (United States)

    Pätynen, Jukka; Lokki, Tapio

    2016-03-01

    An audience's auditory experience during a thrilling and emotive live symphony concert is an intertwined combination of the music and the acoustic response of the concert hall. Music in itself is known to elicit emotional pleasure, and at best, listening to music may evoke concrete psychophysiological responses. Certain concert halls have gained a reputation for superior acoustics, but despite the continuous research by a multitude of objective and subjective studies on room acoustics, the fundamental reason for the appreciation of some concert halls remains elusive. This study demonstrates that room acoustic effects contribute to the overall emotional experience of a musical performance. In two listening tests, the subjects listen to identical orchestra performances rendered in the acoustics of several concert halls. The emotional excitation during listening is measured in the first experiment, and in the second test, the subjects assess the experienced subjective impact by paired comparisons. The results showed that the sound of some traditional rectangular halls provides greater psychophysiological responses and subjective impact. These findings provide a quintessential explanation for these halls' success and reveal the overall significance of room acoustics for emotional experience in music performance.

  3. Calculation of effective electromagnetic parameters of multi-needle zinc oxide whisker based on equivalent spherical particle and strong fluctuation theory

    Science.gov (United States)

    Zhao, Yu-Chen; Liu, Jiang-Fan; Song, Zhong-Guo; Xi, Xiao-Li

    2014-12-01

    Multi-needle zinc oxide whisker (M-ZnOw) includes tetrapod-needle ZnOw (T-ZnOw), flower-shaped ZnOw, and other similar ZnOw architectures. The unique three-dimensional (3D) and multi-needle-shaped structures give the special performance of M-ZnOw, but make it difficult to calculate the effective electromagnetic parameters of M-ZnOw composites. In this paper, based on the equivalent spherical particle and the strong fluctuation theory, three different closed-form expressions are presented to calculate the effective electromagnetic parameters of M-ZnOw composites. To start with, because of the macroscopic isotropic nature of M-ZnOw composites and lossy properties of M-ZnOw itself, an equivalent spherical particle is introduced in the scheme to simplify the unique microscopic structures of M-ZnOw, and the possible limitations of the presented equivalent spherical particle are discussed qualitatively. In addition, different closed-form expressions to calculate the effective electromagnetic parameter are obtained by means of representing the physical situations of conductive network as different correlation functions in the strong fluctuation theory. Finally, the effective permeability of a T-ZnOw/Fe - paraffin composite is calculated by these three expressions in 2-18 GHz frequency range. Very good agreement between the calculated and experimental results on one hand verifies the rationality of presented expressions, and on the other hand indicates that the correlation function plays an important role in improving the performance of the presented expression.

  4. Impact of primary headaches on subjective sleep parameters among adolescents

    Directory of Open Access Journals (Sweden)

    Gupta Ravi

    2008-01-01

    .007. Similarly, values for frequency of nocturnal awakenings per week ( P < 0.001, wake time after sleep onset and offset ( P < 0.001 and 0.002 respectively were the maximum in migraineurs. Only 32.8% migraineurs reported refreshing sleep ( P < 0.001. Post hoc analysis revealed that migraineurs were different from the other two groups on most of the parameters. Conclusions: Sleep disruption is more common in migraineurs than those in the tension type headache sufferers and the control group.

  5. The impact of cardiac resynchronization therapy on routine laboratory parameters

    Science.gov (United States)

    Boros, András Mihály; Perge, Péter; Nagy, Klaudia Vivien; Apor, Astrid; Bagyura, Zsolt; Zima, Endre; Molnár, Levente; Tahin, Tamás; Becker, Dávid; Gellér, László; Merkely, Béla; Széplaki, Gábor

    2017-01-01

    Background Cardiac resynchronization therapy (CRT) in chronic heart failure has been shown to improve mortality and morbidity. However, comprehensive data are not available as concerns how circulating biomarkers reflecting different organ functions, such as serum uric acid, blood urea nitrogen (BUN), albumin, cholesterol, or various liver enzymes, change over time as a consequence of CRT. The aim of this prospective study was to overview these possible changes. Methods A total of 20 routine laboratory parameters were measured in 122 control subjects and in 129 patients with chronic heart failure before CRT, 6 months, and 2 years later. Results The levels of serum uric acid [before: 432 (331–516) mmol/L, 6-month: 372 (304–452) mmol/L, 2-year: 340 (290–433) mmol/L; p < 0.001] and BUN [8.3 (6.4–11.5) mmol/L, 8.0 (6.3–11.1) mmol/L, 6.8 (5.0–9.7) mmol/L; p < 0.001) reduced statistically significant. Total bilirubin underwent reduction [16 (11–23) μmol/L, 11 (7–14) μmol/L, 8 (7–13) μmol/L; p < 0.001], while albumin increased [45 (43–48) g/L, 46 (44–48) g/L, 46 (43–48) g/L; p = 0.04]. Cholesterol concentrations elevated [4.3 (3.6–5.0) mmol/L, 4.5 (3.8–5.1) mmol/L, 4.6 (3.8–5.4) mmol/L; p < 0.001] and glucose decreased [6.2 (5.6–7.2) mmol/L, 5.9 (5.1–6.7) mmol/L, 5.7 (5.1–6.8) mmol/L; p < 0.001]. Conclusions CRT influences the levels of routinely used biomarkers suggesting improvements in renal function, liver capacity, and metabolic changes. These changes could mirror the multiorgan improvement after CRT. PMID:28932489

  6. The impact of cardiac resynchronization therapy on routine laboratory parameters.

    Science.gov (United States)

    Boros, András Mihály; Perge, Péter; Nagy, Klaudia Vivien; Apor, Astrid; Bagyura, Zsolt; Zima, Endre; Molnár, Levente; Tahin, Tamás; Becker, Dávid; Gellér, László; Merkely, Béla; Széplaki, Gábor

    2017-03-01

    Cardiac resynchronization therapy (CRT) in chronic heart failure has been shown to improve mortality and morbidity. However, comprehensive data are not available as concerns how circulating biomarkers reflecting different organ functions, such as serum uric acid, blood urea nitrogen (BUN), albumin, cholesterol, or various liver enzymes, change over time as a consequence of CRT. The aim of this prospective study was to overview these possible changes. A total of 20 routine laboratory parameters were measured in 122 control subjects and in 129 patients with chronic heart failure before CRT, 6 months, and 2 years later. The levels of serum uric acid [before: 432 (331-516) mmol/L, 6-month: 372 (304-452) mmol/L, 2-year: 340 (290-433) mmol/L; p  < 0.001] and BUN [8.3 (6.4-11.5) mmol/L, 8.0 (6.3-11.1) mmol/L, 6.8 (5.0-9.7) mmol/L; p  < 0.001) reduced statistically significant. Total bilirubin underwent reduction [16 (11-23) μmol/L, 11 (7-14) μmol/L, 8 (7-13) μmol/L; p  < 0.001], while albumin increased [45 (43-48) g/L, 46 (44-48) g/L, 46 (43-48) g/L; p  = 0.04]. Cholesterol concentrations elevated [4.3 (3.6-5.0) mmol/L, 4.5 (3.8-5.1) mmol/L, 4.6 (3.8-5.4) mmol/L; p  < 0.001] and glucose decreased [6.2 (5.6-7.2) mmol/L, 5.9 (5.1-6.7) mmol/L, 5.7 (5.1-6.8) mmol/L; p  < 0.001]. CRT influences the levels of routinely used biomarkers suggesting improvements in renal function, liver capacity, and metabolic changes. These changes could mirror the multiorgan improvement after CRT.

  7. Disappearance of flow as a function of impact parameter and energy in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Sullivan, J.P.; Peter, J.; Cussol, D.; Bizard, G.; Brou, R.; Louvel, M.; Patry, J.P.; Regimbart, R.; Steckmeyer, J.C.; Tamain, B.; Cassagnou, Y.; Legrain, R.; Rosato, E.; Hagel, K.; Jin, G.M.; Crema, E.

    1990-05-01

    The dependence of collective nuclear flow on impact parameter and beam energy from 25 to 85 MeV/u has been measured for Ar + Al with the 4π array Mur + Tonneau. The flow of the particles emitted from the interaction region is attributed to scattering at negative angles. When the energy increases, compression gradually opposes this negative scattering, until the flow falls to zero. This is obtained at a beam energy in the range 70-80 MeV/u for impact parameters below 2 fm and increases with the impact parameter. This study as a function of the impact parameter and the energy should allow information both on the nucleon-nucleon cross section in medium and the EOS of nuclear matter to be obtained

  8. Parameter estimation using the genetic algorithm and its impact on quantitative precipitation forecast

    Directory of Open Access Journals (Sweden)

    Y. H. Lee

    2006-12-01

    Full Text Available In this study, optimal parameter estimations are performed for both physical and computational parameters in a mesoscale meteorological model, and their impacts on the quantitative precipitation forecasting (QPF are assessed for a heavy rainfall case occurred at the Korean Peninsula in June 2005. Experiments are carried out using the PSU/NCAR MM5 model and the genetic algorithm (GA for two parameters: the reduction rate of the convective available potential energy in the Kain-Fritsch (KF scheme for cumulus parameterization, and the Asselin filter parameter for numerical stability. The fitness function is defined based on a QPF skill score. It turns out that each optimized parameter significantly improves the QPF skill. Such improvement is maximized when the two optimized parameters are used simultaneously. Our results indicate that optimizations of computational parameters as well as physical parameters and their adequate applications are essential in improving model performance.

  9. A Strong Impact of Genetic Background on Gut Microflora in Mice

    Directory of Open Access Journals (Sweden)

    R. Steven Esworthy

    2010-01-01

    Full Text Available Genetic background affects susceptibility to ileocolitis in mice deficient in two intracellular glutathione peroxidases, GPx1 and GPx2. The C57BL/6 (B6 GPx1/2 double-knockout (DKO mice have mild ileocolitis, and 129S1/Sv (129 DKO mice have severe inflammation. We used diet to modulate ileocolitis; a casein-based defined diet with AIN76A micronutrients (AIN attenuates inflammation compared to conventional LabDiets. Because luminal microbiota induce DKO ileocolitis, we assessed bacterial composition with automated ribosomal intergenic-spacer analysis (ARISA on cecal DNA. We found that mouse strain had the strongest impact on the composition of microbiota than diet and GPx genotypes. In comparing AIN and LabDiet, DKO mice were more resistant to change than the non-DKO or WT mice. However, supplementing yeast and inulin to AIN diet greatly altered microflora profiles in the DKO mice. From 129 DKO strictly, we found overgrowth of Escherichia coli. We conclude that genetic background predisposes mice to colonization of potentially pathogenic E. coli.

  10. Network analysis reveals strongly localized impacts of El Niño

    Science.gov (United States)

    Fan, Jingfang; Meng, Jun; Ashkenazy, Yosef; Havlin, Shlomo; Schellnhuber, Hans Joachim

    2017-07-01

    Climatic conditions influence the culture and economy of societies and the performance of economies. Specifically, El Niño as an extreme climate event is known to have notable effects on health, agriculture, industry, and conflict. Here, we construct directed and weighted climate networks based on near-surface air temperature to investigate the global impacts of El Niño and La Niña. We find that regions that are characterized by higher positive/negative network “in”-weighted links are exhibiting stronger correlations with the El Niño basin and are warmer/cooler during El Niño/La Niña periods. In contrast to non-El Niño periods, these stronger in-weighted activities are found to be concentrated in very localized areas, whereas a large fraction of the globe is not influenced by the events. The regions of localized activity vary from one El Niño (La Niña) event to another; still, some El Niño (La Niña) events are more similar to each other. We quantify this similarity using network community structure. The results and methodology reported here may be used to improve the understanding and prediction of El Niño/La Niña events and also may be applied in the investigation of other climate variables.

  11. Investigation of Impact of the Gate Circuitry on IGBT Transistor Dynamic Parameters

    Directory of Open Access Journals (Sweden)

    Vytautas Bleizgys

    2011-03-01

    Full Text Available The impact of Insulated Gate Bipolar Transistor driver circuit parameters on the rise and fall time of the collector current and voltage collector-emitter was investigated. The influence of transistor driver circuit parameters on heating of Insulated Gate Bipolar Transistors was investigated as well.Article in Lithuanian

  12. Impact factor analysis: combining prediction with parameter ranking to reveal the impact of behavior on health outcome

    DEFF Research Database (Denmark)

    Doryab, Afsaneh; Frost, Mads; Faurholt-Jepsen, Maria

    2015-01-01

    An increasing number of healthcare systems allow people to monitor behavior and provide feedback on health and wellness. Most applications, however, only offer feedback on behavior in form of visualization and data summaries. This paper presents a different approach—called impact factor analysis......—in which machine learning techniques are used to infer the progression of a primary health parameter and then apply parameter ranking to investigate which behavioral data have the highest ‘impact’ on health. We have applied this approach to improve the MONARCA personal health application for patients......, identifying physical activity and sleep as the highest impact parameters. These results revealed the feasibility of identifying behavioral impact factors. This data analysis motivated us to design an impact factor inference engine as part of the MONARCA system. To our knowledge, this is a novel approach...

  13. Impact of meteorological parameters on extracted landfill gas composition and flow

    DEFF Research Database (Denmark)

    Fathi Aghdam, Ehsan; Scheutz, Charlotte; Kjeldsen, Peter

    2018-01-01

    The objective of this study was to investigate the impact of four pre-selected meteorological parameters (barometric pressure, wind speed, ambient temperature and solar radiation) on recovered landfill gas (LFG) flow, methane (CH4) content of the LFG and the recovered CH4 flow by performing...... winter, but not during summer. Ambient temperature and solar radiation were not major meteorological parameters affecting LFG recovery, as low correlation coefficients were observed between these two parameters and the LFG recovery data....

  14. Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, Arnulf; Vaupel, Peter; Stockinger, Marcus; Schmidberger, Heinz [University Medical Center, Department of Radiooncology and Radiotherapy, Mainz (Germany); Struss, Hans-Garlich [University Medical Center, Department of Laboratory Medicine, Mainz (Germany); Giese, Alf [University Medical Center, Department of Neurosurgery, Mainz (Germany)

    2014-10-15

    In comparison to normal brain tissue, glioblastomas exhibit significantly increased glucose uptake. Brain edema is a common complication during adjuvant chemoradiotherapy, leading to a requirement for glucocorticoid treatment. Glucocorticoid treatment frequently causes considerable deregulation of blood glucose levels. Therefore, episodes of hyperglycemia may contribute to radio- and/or chemoresistance. This study comprises a retrospective analysis of the influence of hyperglycemic episodes (HEs) during adjuvant therapy on the overall survival of 106 glioblastoma multiforme patients. The occurrence of one or more deregulated blood glucose value(s) > 10 mM is associated with a reduction in median overall survival from 16.7 to 8.8 months. A significantly poorer overall survival of patients with hyperglycemia could also be detected in subgroup analyses of patients with complete tumor resection and complete treatment according to the EORTC 22891/26891 trial protocol, as well as in a multivariate Cox proportional hazards analysis. A history of diabetes mellitus had no influence on prognosis. Our data suggest that the observed negative impact of elevated blood glucose levels on overall survival may not solely be explained by the patients' poorer general condition; the elevated blood glucose concentration itself may play a pathogenetic role. This could be due to increased activity of antioxidant systems, elevated expression of DNA damage response proteins and protection of hypoxic tumor cells against apoptosis combined with hypoxia-mediated radioresistance. A possible prognostic impact of elevated blood glucose levels during the period of adjuvant (chemo-) radiotherapy of glioblastoma should be evaluated in a prospective clinical trial. (orig.) [German] Glioblastome zeigen im Vergleich mit normalem Gehirngewebe eine deutlich vermehrte Glukoseaufnahme. Im Rahmen der adjuvanten Radio(chemo)therapie von Glioblastomen treten vielfach Hirnoedeme auf, die eine

  15. Analysis of impact of “strong DC and weak AC” on receiving-end power system

    Science.gov (United States)

    Wang, Qiang; Li, Tianran; Yang, Pengcheng

    2018-02-01

    The rapid development of UHVDC transmission project has brought abundant power supply to the receiving-end power system area, but also many security and stability problems. This paper summarizes four elements that affect the strength of AC system, and then simulates the most basic two-terminal single-pole UHV transmission system by MATLAB/Simulink. It analyses the impact of receiving-end AC power system strength on real-time power, frequency and voltage. Finally, in view of operation risk of “strong DC and weak AC”, this paper puts forward three countermeasures.

  16. Impact of aerosols on regional climate in southern and northern China during strong/weak East Asian summer monsoon years

    Science.gov (United States)

    Li, Shu; Wang, Tijian; Solmon, Fabien; Zhuang, Bingliang; Wu, Hao; Xie, Min; Han, Yong; Wang, Xuemei

    2016-04-01

    In this work, we mainly simulate the effects of aerosols on regional climate in southern China (SC) and northern China (NC) and compare the differences of aerosol climatic effects in strong/weak summer monsoon years with a modified regional climate model RegCM4. The results show that the total climatic effects of aerosols cause the decline of averaged air temperature and precipitation of SC and NC in summer. In NC, the strength of temperature drop in strong summer monsoon years is higher than that in weak summer monsoon years, indicating the possible impact from the different changes of radiation, circulation, and precipitation. The decrease of precipitation is more significant in NC in weak summer monsoon years, while it is stronger in SC in strong summer monsoon years due to the difference of aerosol distribution as well as the effects on circulation and cloud microphysics processes. Besides, aerosol effects also cause a decrease of zonal wind at 850 hPa in SC and an increase in NC. The cooling center is more northerly and stronger in strong monsoon year, while it is more southerly and weaker in weak summer monsoon years, which results in the differences of vertical circulation anomaly and meridional wind anomaly at 850 hPa. In weak summer monsoon years, meridional wind at 850 hPa is increased in NC, while it is found to be decreased in SC. In strong summer monsoon years, meridional winds at 850 hPa in both NC and SC are weakened. However, the decrease in SC is much more distinct and clear.

  17. Analysis Of Impact Of Various Parameters On BER Performance For IEEE 802.11b

    Directory of Open Access Journals (Sweden)

    Nilesh B. Kalani

    2015-08-01

    Full Text Available Abstract This paper discusses about IEEE 802.11b simulation model implemented using LabVIEW software and its analyses for impact on bit error rate BER for different parameters as channel type channel number data transmission rate and packet size. Audio file is being transmitted processed and analyzed using the model for various parameters. This paper gives analysis of BER verses ESN0 for various parameter like data rate packet size and communication channel for the IEEE 802.11b simulation model generated using LabVIEW. It is proved that BER can be optimized by tweaking different parameters of wireless communication system.

  18. Implications of the subjectivity in hydrologic model choice and parameter identification on the portrayal of climate change impact

    Science.gov (United States)

    Mendoza, Pablo; Clark, Martyn; Rajagopalan, Balaji; MIzukami, Naoki; Gutmann, Ethan; Newman, Andy; Barlage, Michael; Brekke, Levi; Arnold, Jeffrey

    2014-05-01

    Climate change studies involve several methodological choices that affect the hydrological sensitivities obtained, including emission scenarios, climate models, downscaling techniques and hydrologic modeling approaches. Among these, hydrologic model structure selection (i.e. the set of equations that describe catchment processes) and parameter identification are particularly relevant and usually have a strong subjective component. This subjectivity is not only limited to engineering applications, but also extends to many of our research studies, resulting in problems such as missing processes in our models, inappropriate parameterizations and compensatory effects of model parameters (i.e. getting the right answers for the wrong reasons). The goal of this research is to assess the impact of our modeling decisions on projected changes in water balance and catchment behavior for future climate scenarios. Additionally, we aim to better understand the relative importance of hydrologic model structures and parameters on the portrayal of climate change impact. Therefore, we compare hydrologic sensitivities coming from four different models structures (PRMS, VIC, Noah and Noah-MP) with those coming from parameter sets identified using different decisions related to model calibration (objective function, multiple local optima and calibration forcing dataset). We found that both model structure selection and parameter estimation strategy (objective function and forcing dataset) affect the direction and magnitude of climate change signal. Furthermore, the relative effect of subjective decisions on projected variations of catchment behavior depends on the hydrologic signature measure analyzed. Finally, parameter sets with similar values of the objective function may not affect current and future changes in water balance, but may lead to very different sensitivities in hydrologic behavior.

  19. Impact of precision of Bayesian networks parameters on accuracy of medical diagnostic systems

    Science.gov (United States)

    Oniśko, Agnieszka; Druzdzel, Marek J.

    2014-01-01

    Objective One of the hardest technical tasks in employing Bayesian network models in practice is obtaining their numerical parameters. In the light of this difficulty, a pressing question, one that has immediate implications on the knowledge engineering effort, is whether precision of these parameters is important. In this paper, we address experimentally the question whether medical diagnostic systems based on Bayesian networks are sensitive to precision of their parameters. Methods and Materials The test networks include Hepar II, a sizeable Bayesian network model for diagnosis of liver disorders and six other medical diagnostic networks constructed from medical data sets available through the Irvine Machine Learning Repository. Assuming that the original model parameters are perfectly accurate, we lower systematically their precision by rounding them to progressively courser scales and check the impact of this rounding on the models' accuracy. Results Our main result, consistent across all tested networks, is that imprecision in numerical parameters has minimal impact on the diagnostic accuracy of models, as long as we avoid zeroes among parameters. Conclusion The experiments' results provide evidence that as long as we avoid zeroes among model parameters, diagnostic accuracy of Bayesian network models does not suffer from decreased precision of their parameters. PMID:23466438

  20. A study of the impact of scheduling parameters in heterogeneous computing environments

    Energy Technology Data Exchange (ETDEWEB)

    Powers, Sarah S [ORNL

    2014-01-01

    This paper describes a tool for exploring system scheduler parameter settings in a heterogeneous computing environment. Through the coupling of simulation and optimization techniques, this work investigates optimal scheduling intervals, the impact of job arrival prediction on scheduling, as well as how to best apply fair use policies. The developed simulation framework is quick and modular, enabling decision makers to further explore decisions in real-time regarding scheduling policies or parameter changes.

  1. Periodic window arising in the parameter space of an impact oscillator

    International Nuclear Information System (INIS)

    Medeiros, E.S.; Souza, S.L.T. de; Medrano-T, R.O.; Caldas, I.L.

    2010-01-01

    In the bi-dimensional parameter space of an impact-pair system, shrimp-shaped periodic windows are embedded in chaotic regions. We show that a weak periodic forcing generates new periodic windows near the unperturbed one with its shape and periodicity. Thus, the new periodic windows are parameter range extensions for which the controlled periodic oscillations substitute the chaotic oscillations. We identify periodic and chaotic attractors by their largest Lyapunov exponents.

  2. Impact of beauty and charm H1-ZEUS combined measurements on PDFs and determination of the strong coupling

    Science.gov (United States)

    Vafaee, A.; Khorramian, A.

    2017-11-01

    In this QCD analysis, we investigate the impact of recent measurements of heavy-flavor charm and beauty cross sections data sets on the simultaneous determination of Parton Distribution Functions (PDFs) and the strong coupling, αs(M2Z). We perform three different fits based on Variable-Flavour Number Scheme (VFNS) at the Leading Order (LO) and Next-to-Leading Order (NLO) and choose the full HERA run I and II combined data as a new measurement of inclusive Deep Inelastic Scattering (DIS) cross sections for our base data set. We show that including charm and beauty cross sections data reduces the uncertainty of gluon distribution and improves the fit quality up to 4.1% from leading order to next-to-leading order and up to 1.7% for only NLO without and with beauty and charm data contributions.

  3. Electron-impact coherence parameters for 41 P 1 excitation of zinc

    Science.gov (United States)

    Piwiński, Mariusz; Kłosowski, Łukasz; Chwirot, Stanisław; Fursa, Dmitry V.; Bray, Igor; Das, Tapasi; Srivastava, Rajesh

    2018-04-01

    We present electron-impact coherence parameters (EICP) for electron-impact excitation of 41 P 1 state of zinc atoms for collision energies 40 eV and 60 eV. The experimental results are presented together with convergent close-coupling and relativistic distorted-wave approximation theoretical predictions. The results are compared and discussed with EICP data for collision energies 80 eV and 100 eV.

  4. Strain selection, biomass to biofuel conversion, and resource colocation have strong impacts on the economic performance of algae cultivation sites

    Directory of Open Access Journals (Sweden)

    Erik R. Venteris

    2014-09-01

    Full Text Available Decisions involving strain selection, biomass to biofuel technology, and the location of cultivation facilities can strongly influence the economic viability of an algae-based biofuel enterprise. We summarize our past results in a new analysis to explore the relative economic impact of these design choices. Our growth model is used to predict average biomass production for two saline strains (Nannocloropsis salina, Arthrospira sp., one fresh to brackish strain (Chlorella sp., DOE strain 1412, and one freshwater strain (order Sphaeropleales. Biomass to biofuel conversion is compared between lipid extraction (LE and hydrothermal liquefaction (HTL technologies. National-scale models of water, CO2 (as flue gas, land acquisition, site leveling, construction of connecting roads, and transport of HTL oil to existing refineries are used in conjunction with estimates of fuel value (from HTL to prioritize and select from 88,692 unit farms (UF, 405 ha in pond area, a number sufficient to produce 136E+9 L yr-1 of renewable diesel (36 billion gallons yr-1. Strain selection and choice of conversion technology have large economic impacts, with differences between combinations of strains and biomass to biofuel technologies being up to $10 million dollars yr-1 UF-1. Results based on the most productive strain, HTL-based fuel conversion, and resource costs show that the economic potential between geographic locations within the selection can differ by up to $4 million yr-1 UF-1, with 1.8 BGY of production possible from the most cost-effective sites. The local spatial variability in site rank is extreme, with very high and low sites within 10s of km of each other. Colocation with flue gas sources has a strong influence on rank, but the most costly resource component varies from site to site. The highest rank UFs are located predominantly in Florida and Texas, but most states south of 37°N latitude contain promising locations.

  5. Analysing the Impacts of Various Environmental Parameters on the Biodiversity Status of Major Habitats

    Directory of Open Access Journals (Sweden)

    Lisa Winter

    2017-09-01

    Full Text Available Background: Anthropogenic impacts on the environment often result in loss of biodiversity. However, the effects of different parameters (such as soil pH on biodiversity, which can be influenced by human activities, are poorly investigated on a global scale. The paper at hand proposes an approach to examine the relationship between biodiversity and several parameters, which can be anthropogenically influenced, on a major habitat scale. The goal is to describe the relationship of a single parameter and biodiversity by means of a mathematical model within one major habitat. Methods: Geographic information system (GIS data for the parameters “mean soil pH”, “mean share of cultivated land” and “mean temperature in June” for the whole world were overlaid with GIS data for the ecoregions proposed by the World Wide Fund for Nature (WWF. By means of the software ArcGIS 10.4 (Esri Deutschland GmbH, Kranzberg, Germany, an average parameter value per ecoregion for all considered parameters was determined. Moreover, the index “biodiversity status” was introduced and determined for every ecoregion by means of the indicators “number of species”, “number of endemic species”, and “mean share of grassland and forest” for each ecoregion. As all ecoregions can be assigned to one of the 14 major habitats (as defined by the WWF, a Kruskal–Wallis test was conducted to analyse whether the parameters and the biodiversity status’ differentiate between the 14 major habitats. A mathematical model, which depicts the impact of the parameters on biodiversity, was established by means of curve fitting. Results: The Kruskal–Wallis test reveals that a significant difference (p-value of 0.000 regarding the considered parameter and the biodiversity status exists between the different major habitats. By means of a regression analysis and curve fitting, mathematical models were developed which describe the relation of the biodiversity status and the

  6. Fine tuning of track impact parameter resolution of the DELPHI detector

    CERN Document Server

    Borisov, G

    1996-01-01

    The fine tuning of the charged track impact parameter resolution for data and simulation in the DELPHI detector at LEP is described. This tuning was implemented in the software for the tagging of $B$ hadrons and has been applied in many precise measurements.

  7. Impact parameter dependence of K-shell ionization in Cu-Cu collisions

    International Nuclear Information System (INIS)

    Frank, W.; Jaracz, P.; Kaun, K.-H.; Lenk, M.; Rudiger, J.; Stachura, Z.

    1980-01-01

    The impact parameter dependence of the yield of K-shell vacancy production in 1 MeV/ a.m.u. Cu-Cu collisions has been studied in an X-ray-scattered ion coincidence experiment. The results are compared with existing models for K-vacancy production

  8. Investigating the Impact of Item Parameter Drift for Item Response Theory Models with Mixture Distributions

    Directory of Open Access Journals (Sweden)

    Yoon Soo ePark

    2016-02-01

    Full Text Available This study investigates the impact of item parameter drift (IPD on parameter and ability estimation when the underlying measurement model fits a mixture distribution, thereby violating the item invariance property of unidimensional item response theory (IRT models. An empirical study was conducted to demonstrate the occurrence of both IPD and an underlying mixture distribution using real-world data. Twenty-one trended anchor items from the 1999, 2003, and 2007 administrations of Trends in International Mathematics and Science Study (TIMSS were analyzed using unidimensional and mixture IRT models. TIMSS treats trended anchor items as invariant over testing administrations and uses pre-calibrated item parameters based on unidimensional IRT. However, empirical results showed evidence of two latent subgroups with IPD. Results showed changes in the distribution of examinee ability between latent classes over the three administrations. A simulation study was conducted to examine the impact of IPD on the estimation of ability and item parameters, when data have underlying mixture distributions. Simulations used data generated from a mixture IRT model and estimated using unidimensional IRT. Results showed that data reflecting IPD using mixture IRT model led to IPD in the unidimensional IRT model. Changes in the distribution of examinee ability also affected item parameters. Moreover, drift with respect to item discrimination and distribution of examinee ability affected estimates of examinee ability. These findings demonstrate the need to caution and evaluate IPD using a mixture IRT framework to understand its effect on item parameters and examinee ability.

  9. Investigating the Impact of Item Parameter Drift for Item Response Theory Models with Mixture Distributions.

    Science.gov (United States)

    Park, Yoon Soo; Lee, Young-Sun; Xing, Kuan

    2016-01-01

    This study investigates the impact of item parameter drift (IPD) on parameter and ability estimation when the underlying measurement model fits a mixture distribution, thereby violating the item invariance property of unidimensional item response theory (IRT) models. An empirical study was conducted to demonstrate the occurrence of both IPD and an underlying mixture distribution using real-world data. Twenty-one trended anchor items from the 1999, 2003, and 2007 administrations of Trends in International Mathematics and Science Study (TIMSS) were analyzed using unidimensional and mixture IRT models. TIMSS treats trended anchor items as invariant over testing administrations and uses pre-calibrated item parameters based on unidimensional IRT. However, empirical results showed evidence of two latent subgroups with IPD. Results also showed changes in the distribution of examinee ability between latent classes over the three administrations. A simulation study was conducted to examine the impact of IPD on the estimation of ability and item parameters, when data have underlying mixture distributions. Simulations used data generated from a mixture IRT model and estimated using unidimensional IRT. Results showed that data reflecting IPD using mixture IRT model led to IPD in the unidimensional IRT model. Changes in the distribution of examinee ability also affected item parameters. Moreover, drift with respect to item discrimination and distribution of examinee ability affected estimates of examinee ability. These findings demonstrate the need to caution and evaluate IPD using a mixture IRT framework to understand its effects on item parameters and examinee ability.

  10. Strain selection, biomass to biofuel conversion, and resource colocation have strong impacts on the economic performance of algae cultivation sites

    Energy Technology Data Exchange (ETDEWEB)

    Venteris, Erik R.; Wigmosta, Mark S.; Coleman, Andre M.; Skaggs, Richard

    2014-09-16

    Decisions involving strain selection, biomass to biofuel technology, and the location of cultivation facilities can strongly influence the economic viability of an algae-based biofuel enterprise. In this contribution we summarize our past results in a new analysis to explore the relative economic impact of these design choices. We present strain-specific growth model results from two saline strains (Nannocloropsis salina, Arthrospira sp.), a fresh to brackish strain (Chlorella sp., DOE strain 1412), and a freshwater strain of the order Sphaeropleales. Biomass to biofuel conversion is compared between lipid extraction (LE) and hydrothermal liquefaction (HTL) technologies. National-scale models of water, CO2 (as flue gas), land acquisition, site leveling, construction of connecting roads, and transport of HTL oil to existing refineries are used in conjunction with estimates of fuel value (from HTL) to prioritize and select from 88,692 unit farms (UF, 405 ha in pond area), a number sufficient to produce 136E+9 L yr-1 of renewable diesel (36 billion gallons yr-1, BGY). Strain selection and choice of conversion technology have large economic impacts, with differences between combinations of strains and biomass to biofuel technologies being up to $10 million dollars yr-1 UF-1. Results based on the most productive species, HTL-based fuel conversion, and resource costs show that the economic potential between geographic locations within the selection can differ by up to $4 million yr-1 UF-1, with 2.0 BGY of production possible from the most cost-effective sites. The local spatial variability in site rank is extreme, with very high and low rank sites within 10s of km of each other. Colocation with flue gas sources has a strong influence on site rank, but the most costly resource component varies from site to site. The highest rank sites are located predominantly in Florida and Texas, but most states south of 37°N latitude contain promising locations. Keywords: algae

  11. The Impact of Three Factors on the Recovery of Item Parameters for the Three-Parameter Logistic Model

    Science.gov (United States)

    Kim, Kyung Yong; Lee, Won-Chan

    2017-01-01

    This article provides a detailed description of three factors (specification of the ability distribution, numerical integration, and frame of reference for the item parameter estimates) that might affect the item parameter estimation of the three-parameter logistic model, and compares five item calibration methods, which are combinations of the…

  12. Impact parameter dependent light particle correlations for 40Ar induced reactions on 197Au at E/A = 60 MeV

    International Nuclear Information System (INIS)

    Kyanowski, A.

    1987-01-01

    With the help of a multidetector system of 96 plastic detectors, mounted in the forward hemisphere between 3 0 and 30 0 , we measured light charged particles to make an off-line event-type selection. The final aim to distinguish different impact parameter domains with the plastic wall could be achieved using the observed multiplicity as the sampling parameter. With the help of a computer simulation based on a participant-spectator model to describe the reation, the mean observed multiplicity could be established to vary smoothly with the total multiplicity, a variable which is often cited as an indicator for the violence of a reaction. Even if the simulation indicates a broad distribution of the observed multiplicity over the different impact parameters, we could separate the extreme cases of peripheral and central collisions. If the events are selected with the appropriate multiplicity gates, it turns out that peripheral collisions give rise to enhanced correlations, whereas the correlation function is strongly reduced for central collisions. Between these extreme values the correlation reduces smoothly with the impact parameter. The space-time extent of the emitting system is therefore larger for small impact parameters than in peripheral collisions. Supposing that the spatial extent is rather independent of the impact parameter (except for very peripheral collisions) we suggest that the observed variation of the correlation function could indicate a variation of the emission time for light particles rather than a spatial evolution. On the contrary the temperature, determined equally after an event-type selection with the observed multiplicity, shows no variation with the impact parameter. This could indicate that a limiting temperature is reached at a value at which the emission of particles is faster than the temporal development of the temperature. (orig./HSI)

  13. Impact parameter representation of the leading proton spectrum in the diffractive region

    CERN Document Server

    Barshay, S

    1975-01-01

    Recent experiment indicates that there is no limiting value for the pion invariant inclusive cross section at x=0 at the highest energies reached by the CERN intersecting storage rings. The author first notes that a recently proposed integral representation of the leading proton spectrum is physically equivalent to representing this spectrum in terms of very narrow multiplicity distributions from each initial impact parameter, with a single factorizable function for the average multiplicity at any impact parameter b, (n(s, b/R(s)))=N(s)n(b/R(s)). He then observes that, in this approach, the explicit form for the scaled part of the spectrum for mod x mod <0.97 and p/sub T/ approximately 0 depends essentially upon the assumed asymptotic form for the growth of average multiplicity with energy s. The data do not exclude the empirical possibility of N(s varies as s/sup epsilon /, epsilon <1/4. (19 refs).

  14. Evaluation of risk impact of changes to surveillance requirements addressing model and parameter uncertainties

    International Nuclear Information System (INIS)

    Martorell, S.; Villamizar, M.; Martón, I.; Villanueva, J.F.; Carlos, S.; Sánchez, A.I.

    2014-01-01

    This paper presents a three steps based approach for the evaluation of risk impact of changes to Surveillance Requirements based on the use of the Probabilistic Risk Assessment and addressing identification, treatment and analysis of model and parameter uncertainties in an integrated manner. The paper includes also an example of application that focuses on the evaluation of the risk impact of a Surveillance Frequency change for the Reactor Protection System of a Nuclear Power Plant using a level 1 Probabilistic Risk Assessment. Surveillance Requirements are part of Technical Specifications that are included into the Licensing Basis for operation of Nuclear Power Plants. Surveillance Requirements aim at limiting risk of undetected downtimes of safety related equipment by imposing equipment operability checks, which consist of testing of equipment operational parameters with established Surveillance Frequency and Test Strategy

  15. Determination of minimum impact parameter by modified touching spheres schemes for intermediate energy Coulomb excitation experiments

    International Nuclear Information System (INIS)

    Kumar, Rajiv; Sharma, Shagun; Singh, Pradeep; Kharab, Rajesh

    2016-01-01

    The energy-independent touching spheres schemes commonly used for the determination of the safe minimum value of the impact parameter for Coulomb excitation experiments are modified through the inclusion of an energy-dependent term. The touching spheres+3fm scheme after modification emerges out to be the best one while touching spheres+4fm scheme is found to be better in its unmodified form. (orig.)

  16. Search for impact-parameter dependence of two-particle correlations using exclusive observables

    International Nuclear Information System (INIS)

    Ardouin, D.; Delagrange, H.; Doubre, H.; Gregoire, C.; Mittig, W.; Peghaire, A.; Peter, J.; Saint-Laurent, F.; Bizard, G.; Lefebvres, F.; Tamain, B.; Kyanowski, A.; Quebert, J.; Viyogi, Y.P.

    1986-01-01

    In order to provide detailed information about the dynamics of Heavy-Ion Collisions, it is necessary to perform experiments with exclusive observables to be able to select different impact-parameters domains, various degrees of the evolution of processes leading to possible equilibrium and competing forms of energy like potential and thermal energies. Two-particle correlations measurements in triple-coincidence with a multidetector plasticwall array are presented and shown to offer such possible filters. (orig.)

  17. Impact parameter measurements in nucleus-nucleus collisions at the ISR

    International Nuclear Information System (INIS)

    Frankel, S.

    1981-01-01

    There are two complementary ways to measure impact parameters in nucleus-nucleus collisions. A collision between two nuclei with atomic number A is illustrated, the overlap of N nucleons in each nucleus determined by the geometric impact parameter. The non-interacting A-N nucleons, the spectators, are roughly confined to an inner cone surrounding the incident projectile direction. They consist of fragments from A-N to 1. The transverse momentum distributions has been measured at energies of 1 to 2 GeV/nucleon and recently at the ISR (by group 418) at 500GeV/nucleon. The distribution at both energies fall exponentially with the square of the transverse momentum. The falloff is twice as slow at 1000 as compared with 2 GeV/c. This is the result of the very large multiplicity at ISR energies, the pions blowing out the fragments. The important feature to understand is that these fragments are essentially independent of the mechanisms that take place in the interaction between the 2N interacting nucleons. Therefore the detection of the number of nucleons in this region is a mechanism independent way to measure the impact parameter

  18. A review of Environmental Impact Assessment parameters required for set up of a hydropower project

    Energy Technology Data Exchange (ETDEWEB)

    Roy, Pankaj Kumar; Mazumdar, Asis [Jadavpur Univ. (India). School of Water Resources Engineering

    2013-07-01

    Environmental Impact Assessment in general, hydro-meteorological conditions, topography, hydrology, water availability analysis of a river system, importance of hydropower and feasibility study of Environmental Impact assessment due to the construction of the hydropower plant have been discussed in this research work. The site selection is one of the major components so far the hydropower is concerned and also the minimum flow should have known to us so that the capacity of a hydropower plant can be predicted. The sustainable flow, which refers the flow is available throughout the year, has been calculated based on flow duration curve. This study highlights the environmental impact assessment particularly related to hydropower project. Here the study area a district town located in the eastern region of India on the banks of river Kosi has been considered. The historical rainfall and the river discharge data have been collected from various organizations. The stage-discharge correlation and hydrological parameters related to hydropower have been analyzed and also to discuss the review of environmental impact assessment in hydropower project. The EIA analysis can be also carried out by using fuzzy logic wherein the EIA parameters can be given different weight-age based on the various survey reports that have been carried out at different places at different time. Such analysis has also been provided below based on the various data obtained.

  19. Impact of fitting algorithms on errors of parameter estimates in dynamic contrast-enhanced MRI

    Science.gov (United States)

    Debus, C.; Floca, R.; Nörenberg, D.; Abdollahi, A.; Ingrisch, M.

    2017-12-01

    Parameter estimation in dynamic contrast-enhanced MRI (DCE MRI) is usually performed by non-linear least square (NLLS) fitting of a pharmacokinetic model to a measured concentration-time curve. The two-compartment exchange model (2CXM) describes the compartments ‘plasma’ and ‘interstitial volume’ and their exchange in terms of plasma flow and capillary permeability. The model function can be defined by either a system of two coupled differential equations or a closed-form analytical solution. The aim of this study was to compare these two representations in terms of accuracy, robustness and computation speed, depending on parameter combination and temporal sampling. The impact on parameter estimation errors was investigated by fitting the 2CXM to simulated concentration-time curves. Parameter combinations representing five tissue types were used, together with two arterial input functions, a measured and a theoretical population based one, to generate 4D concentration images at three different temporal resolutions. Images were fitted by NLLS techniques, where the sum of squared residuals was calculated by either numeric integration with the Runge–Kutta method or convolution. Furthermore two example cases, a prostate carcinoma and a glioblastoma multiforme patient, were analyzed in order to investigate the validity of our findings in real patient data. The convolution approach yields improved results in precision and robustness of determined parameters. Precision and stability are limited in curves with low blood flow. The model parameter ve shows great instability and little reliability in all cases. Decreased temporal resolution results in significant errors for the differential equation approach in several curve types. The convolution excelled in computational speed by three orders of magnitude. Uncertainties in parameter estimation at low temporal resolution cannot be compensated by usage of the differential equations. Fitting with the convolution

  20. Impact of maternal fasting during Ramadan on growth parameters of exclusively breastfed infants in Shahroud, 2012

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    Hossein Haratipour

    2013-11-01

    Full Text Available Introduction: There are many advantages in breastfeeding of infants. The impact of fasting of breastfeeding mothers during Ramadan, on their exclusively breastfed infants’ growth, is still unclear. The objective of this study is to determine the impact of maternal Ramadan fasting on growth parameters of exclusively breastfed infants. Methods: This cohort study was conducted on 55 healthy, exclusively breastfed infants, aged 1 to 6 months, during Ramadan and three months after it. 20 infants, whose mothers fasted throughout Ramadan (case group and 35 infants, whose mothers did not fast (control group, were enrolled in the study. All infants underwent periodic physical examinations, twice in Ramadan and 3 times in the first, second and the third months after Ramadan. The data analyses were done using a repeated measure analysis of variance. Statistical significance was defined as PFindings: The average age was 3.43±1.38 months in the case group and 2.31±1.45 months in the control group that presence no significant difference between. From the total number of infants, 23 cases (41.8% were males and the rest were females. All growth parameters increased during the study period (P< 0.05, with the same rate of increase for both groups (P=0.125. Conclusion: Ramadan fasting by breastfeeding mothers did not adversely affect the growth parameters of exclusively breastfed infants in short-term.

  1. Exposure to environmental tobacco smoke from husband more strongly impacts on the airway obstruction of nonsmoking women

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    Suyama K

    2017-12-01

    Full Text Available Kazuaki Suyama, Ryo Kozu, Takako Tanaka, Yuji Ishimatsu, Terumitsu Sawai Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan Background: The impact of airway obstruction of nonsmoking women caused by their husband’s smoking is unclear, despite the association between environmental tobacco smoke (ETS exposure at home and obstructive pulmonary diseases among nonsmoking women. The aim of this study was to provide evidence that ETS exposure from the husband at home has a more significant influence on the airway obstruction of nonsmoking women than other housemates. Participants and methods: Nonsmoking women aged 40 years or older were recruited from the health checkup during May 2015–December 2016, Japan. They answered structured questionnaires, including ETS exposure from their husbands and other housemates (parents, siblings and dependants, and performed spirometry. We categorized the women with any history of ETS exposure from housemates into three groups (A = husband, B = others and C = both of husband and others and defined the control group as those with no ETS exposure from housemates. Results: A total of 811 nonsmoking women completed questionnaires and spirometry. The proportion of nonsmoking women who had airway obstruction (forced expiratory volume in 1 second [FEV1]/forced vital capacity [FVC] <70% among Group A (7.5% was significantly higher than those in the control group (1.1%, p<0.01 and Group B (0.8%, p<0.01. The proportion of airway obstruction in Group C (6.4% was also higher than that in the control group (p<0.05 and Group B (p<0.05. ETS exposure from husband (odds ratio [OR], 3.53; 95% confidence interval [CI], 1.48–8.42 remained strongly associated with airway obstruction after multiple logistic regression analysis, adjusting for age, housemate’s smoking habits, family history and ETS exposure in childhood and at work. Conclusion: Nonsmoking

  2. Impact of Plasmodium falciparum infection on haematological parameters in children living in Western Kenya

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    Hongo Gordon

    2010-12-01

    Full Text Available Abstract Background Malaria is the commonest cause of childhood morbidity in Western Kenya with varied heamatological consequences. The t study sought to elucidate the haemotological changes in children infected with malaria and their impact on improved diagnosis and therapy of childhood malaria. Methods Haematological parameters in 961 children, including 523 malaria-infected and 438 non-malaria infected, living in Kisumu West District, an area of malaria holoendemic transmission in Western Kenya were evaluated. Results The following parameters were significantly lower in malaria-infected children; platelets, lymphocytes, eosinophils, red blood cell count and haemoglobin (Hb, while absolute monocyte and neutrophil counts, and mean platelet volume (MPV were higher in comparison to non-malaria infected children. Children with platelet counts of Conclusion Children infected with Plasmodium falciparum malaria exhibited important changes in some haematological parameters with low platelet count and haemoglobin concentration being the two most important predictors of malaria infection in children in our study area. When used in combination with other clinical and microscopy, these parameters could improve malaria diagnosis in sub-patent cases.

  3. Impact of a community-based diabetes self-management program on key metabolic parameters

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    Johnson C

    2014-12-01

    Full Text Available Objective: Characterize the impact of a pharmacist-led diabetes self-management program on three key metabolic parameters: glycosylated hemoglobin (HbA1c, low-density lipoprotein cholesterol (LDL-C, and mean arterial blood pressure (MAP among employee health program participants. Methods: A self-insured company in the Kansas City metropolitan area began offering a pharmacist-led diabetes self-management program to eligible company employees and their dependents in 2008. A retrospective pre-post analysis was conducted to determine if the program affected key metabolic parameters in participants by determining mean change after one year of participation. Results: Among 183 program participants, 65 participants met inclusion criteria. All three key metabolic parameters were significantly reduced from baseline to one year of program participation: HbA1c decreased from 8.1% to 7.3% (p=0.007; LDL-C decreased from 108.3 mg/dL to 96.4 mg/dL (p=0.009; and MAP decreased from 96.1 to 92.3 mm Hg (p=0.005. Conclusions: The pharmacist-led diabetes self-management program demonstrated significant reductions in HbA1c, LDL-C, and MAP from baseline to one year of program participation. Improvements were statistically significant and clinically relevant for each parameter. Previous studies indicate these reductions may cause reduced overall healthcare costs.

  4. Impact of Reservoir Fluid Saturation on Seismic Parameters: Endrod Gas Field, Hungary

    Science.gov (United States)

    El Sayed, Abdel Moktader A.; El Sayed, Nahla A.

    2017-12-01

    Outlining the reservoir fluid types and saturation is the main object of the present research work. 37 core samples were collected from three different gas bearing zones in the Endrod gas field in Hungary. These samples are belonging to the Miocene and the Upper - Lower Pliocene. These samples were prepared and laboratory measurements were conducted. Compression and shear wave velocity were measured using the Sonic Viewer-170-OYO. The sonic velocities were measured at the frequencies of 63 and 33 kHz for compressional and shear wave respectively. All samples were subjected to complete petrophysical investigations. Sonic velocities and mechanical parameters such as young’s modulus, rigidity, and bulk modulus were measured when samples were saturated by 100%-75%-0% brine water. Several plots have been performed to show the relationship between seismic parameters and saturation percentages. Robust relationships were obtained, showing the impact of fluid saturation on seismic parameters. Seismic velocity, Poisson’s ratio, bulk modulus and rigidity prove to be applicable during hydrocarbon exploration or production stages. Relationships among the measured seismic parameters in gas/water fully and partially saturated samples are useful to outline the fluid type and saturation percentage especially in gas/water transitional zones.

  5. Impact of athletic recovery parameters of hemodynamics in disabled powerlifters with cerebral palsy

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    T. Prystypa

    2017-04-01

    Full Text Available Sport as one of physical culture components renders extremely complex impact on various environments and is enormously popular. In Poland disabled powerlifting represents top world standards. Aim of work: aims at examination of impact of biological regeneration on blood pressure and pulse in CP class 4, 5, 6, 7, 8 disabled power-lifters with normal upper extremities function. Material: The research material comprised twenty 18-30 years old disabled power-lifters with cerebral palsy and normal function of upper extremities who are active members of "Start-Impel" sports club in Wroclaw. The research was carried out in 2 identical cycles on the same disabled sportsmen. Cycle I comprised primary research, while Cycle II, as secondary research, was carried out 5 months later. The micro-cycles were identical as regards training and biological regeneration schedules on particular weekdays, which guaranteed optimal research conditions. Results: Results of the research allowed formation of the following parameters of pressure and pulse dynamics: 1. Post-training systolic blood pressure shows increasing dynamics; 2. During training meso-cycle with biological regeneration in Group A systolic pressure parameters were considerably lower than during the meso-cycle without biological renovation; 3. Diastolic pressure measured before training in both groups remains at 70-80 mm Hg, while post-training pressure increases to 82-86 mm Hg; 4. Post-training pulse measures are always higher than starting measures. Conclusions: Combination of strength training and complex biological regeneration has positive impact on dynamics of blood pressure and pulse hemodynamic parameters, which in turn boosts training effectiveness.

  6. Impact parameter dependence of inelasticity in pp/pp-bar collisions

    Energy Technology Data Exchange (ETDEWEB)

    Beggio, P.C., E-mail: beggio@uenf.br [Laboratorio de Ciencias Matematicas, Universidade Estadual do Norte Fluminense Darcy Ribeiro - UENF, Campos dos Goytacazes - RJ (Brazil)

    2011-08-01

    We study the impact parameter dependence of inelasticity in the framework of an updated geometrical model for multiplicity distribution. A formula in which the inelasticity is related to the eikonal is obtained. This framework permits a calculation of the multiplicity distributions as well as the inelasticity once the eikonal function is given. Adopting a QCD inspired parametrization for the eikonal, in which the gluon-gluon contribution dominates at high energy and determines the asymptotic behavior of the cross sections, we find that the inelasticity decreases as collision energy is increased. Our results predict the KNO scaling violation observed at LHC energies by CMS Collaboration.

  7. Impact of Various Parameters on the Performance of Inter-aircraft Optical Wireless Communication Link

    Science.gov (United States)

    Singh, Mehtab

    2017-12-01

    Optical wireless communication (OWC) systems also known as Free space optics (FSO) are capable of providing high channel bandwidth, high data transmission rates, low power consumption, and high security. OWC links are being considered in different applications such as inter-satellite links, terrestrial links, and inter-aircraft communication links. This paper investigates the impact of different system parameters such as transmission power level, operating wavelength, transmitter pointing error angle, bit transmission rate, atmospheric attenuation, antenna aperture diameter, geometric losses, the responsivity of the photodetector, and link range on the performance of inter-aircraft optical wireless communication link.

  8. Bubble jet impact on a rigid wall of different stand-off parameters

    International Nuclear Information System (INIS)

    Li, S; Wang, S P; Zhang, A M

    2015-01-01

    One of the key features of the dynamics of a bubble near a rigid wall is the development of a high liquid jet, generating highly localized pressure on the wall. In present study, the boundary integral method is employed to simulate this phenomenon, and the vortex ring model is introduced to handle the discontinued potential of the toroidal bubble. Meanwhile, the pressure induced in the whole process is calculated by an auxiliary function. The effect of the stand-off parameter on the bubble dynamics and the pressure on the wall is investigated, and a double-peaked structure occurs in the pressure profile after the jet impact in some cases, which is associated with the jet impact and the high internal pressure inside the bubble

  9. The strong prognostic value of KELIM, a model-based parameter from CA 125 kinetics in ovarian cancer: data from CALYPSO trial (a GINECO-GCIG study).

    Science.gov (United States)

    You, Benoit; Colomban, Olivier; Heywood, Mark; Lee, Chee; Davy, Margaret; Reed, Nicholas; Pignata, Sandro; Varsellona, Nenzi; Emons, Günter; Rehman, Khalid; Steffensen, Karina Dahl; Reinthaller, Alexander; Pujade-Lauraine, Eric; Oza, Amit

    2013-08-01

    Unexpected results were recently reported about the poor surrogacy of Gynecologic Cancer Intergroup (GCIG) defined CA-125 response in recurrent ovarian cancer (ROC) patients. Mathematical modeling may help describe CA-125 decline dynamically and discriminate prognostic kinetic parameters. Data from CALYPSO phase III trial comparing 2 carboplatin-based regimens in ROC patients were analyzed. Based on population kinetic approach, serum [CA-125] concentration-time profiles during first 50 treatment days were fit to a semi-mechanistic model with following parameters: "d[CA-125]/dt=(KPROD∗exp (BETA∗t))∗Effect-KELIM∗[CA-125]" with time, t; tumor growth rate, BETA; CA-125 tumor production rate, KPROD; CA-125 elimination rate, KELIM and K-dependent treatment indirect Effect. The predictive values of kinetic parameters were tested regarding progression-free survival (PFS) against other reported prognostic factors. Individual CA-125 kinetic profiles from 895 patients were modeled. Three kinetic parameters categorized by medians had predictive values using univariate analyses: K; KPROD and KELIM (all PCA-125 response (favoring carboplatin-paclitaxel arm), treatment arm, platinum free-interval, measurable lesions and KELIM (HR=0.53; 95% CI 0.45-0.61; PCA-125 kinetics in ROC patients enables understanding of the time-change components during chemotherapy. The contradictory surrogacy of GCIG-defined CA-125 response was confirmed. The modeled CA-125 elimination rate KELIM, potentially assessable in routine, may have promising predictive value regarding PFS. Further validation of this predictive marker is warranted. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. The impact of spatial variability of hydrogeological parameters - Monte Carlo calculations using SITE-94 data

    International Nuclear Information System (INIS)

    Pereira, A.; Broed, R.

    2002-03-01

    In this report, several issues related to the probabilistic methodology for performance assessments of repositories for high-level nuclear waste and spent fuel are addressed. Random Monte Carlo sampling is used to make uncertainty analyses for the migration of four nuclides and a decay chain in the geosphere. The nuclides studied are cesium, chlorine, iodine and carbon, and radium from a decay chain. A procedure is developed to take advantage of the information contained in the hydrogeological data obtained from a three-dimensional discrete fracture model as the input data for one-dimensional transport models for use in Monte Carlo calculations. This procedure retains the original correlations between parameters representing different physical entities, namely, between the groundwater flow rate and the hydrodynamic dispersion in fractured rock, in contrast with the approach commonly used that assumes that all parameters supplied for the Monte Carlo calculations are independent of each other. A small program is developed to allow the above-mentioned procedure to be used if the available three-dimensional data are scarce for Monte Carlo calculations. The program allows random sampling of data from the 3-D data distribution in the hydrogeological calculations. The impact of correlations between the groundwater flow and the hydrodynamic dispersion on the uncertainty associated with the output distribution of the radionuclides' peak releases is studied. It is shown that for the SITE-94 data, this impact can be disregarded. A global sensitivity analysis is also performed on the peak releases of the radionuclides studied. The results of these sensitivity analyses, using several known statistical methods, show discrepancies that are attributed to the limitations of these methods. The reason for the difficulties is to be found in the complexity of the models needed for the predictions of radionuclide migration, models that deliver results covering variation of several

  11. Step length appears to be a strong discriminant gait parameter for elderly females highly concerned about falls: a cross-sectional observational study.

    Science.gov (United States)

    Kirkwood, Renata Noce; de Souza Moreira, Bruno; Vallone, Márcia L D C; Mingoti, Sueli Aparecida; Dias, Rosângela Corrêa; Sampaio, Rosana Ferreira

    2011-06-01

    To determine if gait parameters and the Timed Up and Go test can discriminate between elderly females with high and low concern about falls. Knowledge of these parameters could help in the development of rehabilitation programmes focused on the prevention of falls, fear of falling and functional decline. Cross-sectional, observational study. Human motion laboratory. One hundred and fifty-four elderly females (aged 64 to 83 years), divided into two groups based on their Falls Efficacy Scale International score: high concern (n=81) and low concern (n=73) about falls. Eight gait parameters recorded with the GAITRite system and the Timed Up and Go test score. Factor 2 (composed of step length, gait velocity and Timed Up and Go mobility test) explained 20% of the variability of the data and was the only factor to discriminate between the groups, with 63% correct classifications. Step length proved to be the variable with the greatest discriminant ability, with a much higher discriminant coefficient (0.889) than the Timed Up and Go test (-0.369) and gait velocity (-0.268). High concern about falls is primarily associated with decreased step length. Step length could be used as a screening tool to identify elderly women with low and high concern about falls in order to target these groups in a rehabilitation programme aimed to slow reduction in gait velocity and mobility. Copyright © 2010 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  12. Impact of various parameters in detecting chromosomal aberrations by FISH to describe radiosensitivity

    International Nuclear Information System (INIS)

    Keller, U.; Mueller, E.; Grabenbauer, G.; Sauer, R.; Distel, L.; Kuechler, A.; Liehr, T.

    2004-01-01

    Background and purpose: analysis of radiation-induced chromosomal aberrations is regarded as the ''gold standard'' for classifying individual radiosensitivity. A variety of different parameters can be used. The crucial question, however, is to explore which parameter is suited best to describe the differences between patients with increased radiosensitivity and healthy individuals. Patients and methods: in this study, five patients with severe radiation-induced late effects of at least grade 3, classified according to the Radiation Therapy Oncology Group (RTOG), and eleven healthy individuals were examined retrospectively. Peripheral blood lymphocytes were irradiated in vitro with 0.7 Gy and 2.0 Gy prior to cultivation and stained by means of three-color fluorescence in situ hybridization (FISH). The detailed analysis was focused on the number of breaks per metaphase, on breaks from complex chromosomal rearrangements per metaphase, as well as on the percentage of translocations, dicentric chromosomes, breaks, and excess acentric fragments - each in comparison with the total number of mitoses analyzed. Results: using the number of breaks from complex chromosomal rearrangements after 2.0 Gy, radiosensitive patients as endpoint were clearly to be distinguished (p = 0.001) from healthy individuals. Translocations (p = 0.001) as well as breaks per metaphase (p = 0.002) were also suitable indicators for detecting differences between patients and healthy individuals. The parameters ''percentage of dicentric chromosomes'', ''breaks'', and ''excess acentric fragments'' in comparison to the total number of mitoses analyzed could neither serve as meaningful nor as significant criteria, since they showed a strong interindividual variability. Conclusion: to detect a difference in chromosomal aberrations between healthy and radiosensitive individuals, the parameters ''frequency of breaks per metaphase'', ''complex chromosomal rearrangements'', and ''translocations'' are most

  13. THE IMPACT OF IN VIVO ADMINISTRATION OF A SYNTHESIS PRODUCT (BY-PRODUCT OF SALICYLIC ACID ON SOME BIOCHEMICAL PARAMETERS ON RATS

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    LETITIA STANA

    2013-12-01

    Full Text Available The goal of this study is to establish the in vivo impact of a by-product of salicylic acid, 5-cloro-2-hidroxy-azotyl-sulfamoil-phenyl benzamyde synthesis product (5ClSA-SA, synthesized at the Technical University, Faculty of Industrial Chemistry of Timisoara, on some parameters of energetic metabolism. The experimental results shows that the synthesis product has induced a strong significant increase (p<0.01 of glycemia compared to tests, in direct relation with administration period and a fluctuation of cholesterol values with decrease followed by strong significant increase (p<0.01 compared to tests. Glycemia and plasmatic cholesterol values were situated between physiological limits. Triglycerides registered strong significant increases (p<0.01 in direct relation with administration period, over the physiological limits.

  14. Impact of atrial fibrillation on the cardiovascular system through a lumped-parameter approach.

    Science.gov (United States)

    Scarsoglio, Stefania; Guala, Andrea; Camporeale, Carlo; Ridolfi, Luca

    2014-11-01

    Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and bioengineering sciences. However, some important feedback mechanisms are still not clearly established. The present study aims at understanding the global response of the cardiovascular system during paroxysmal AF through a lumped-parameter approach, which is here performed paying particular attention to the stochastic modeling of the irregular heartbeats and the reduced contractility of the heart. AF can be here analyzed by means of a wide number of hemodynamic parameters and avoiding the presence of other pathologies, which usually accompany AF. Reduced cardiac output with correlated drop of ejection fraction and decreased amount of energy converted to work by the heart during blood pumping, as well as higher left atrial volumes and pressures are some of the most representative results aligned with the existing clinical literature and here emerging during acute AF. The present modeling, providing new insights on cardiovascular variables which are difficult to measure and rarely reported in literature, turns out to be an efficient and powerful tool for a deeper comprehension and prediction of the arrythmia impact on the whole cardiovascular system.

  15. Influence of in-medium NN cross sections, symmetry potential, and impact parameter on isospin observables

    Science.gov (United States)

    Zhang, Yingxun; Coupland, D. D. S.; Danielewicz, P.; Li, Zhuxia; Liu, Hang; Lu, Fei; Lynch, W. G.; Tsang, M. B.

    2012-02-01

    We explore the influence of the in-medium nucleon-nucleon cross section, symmetry potential, and impact parameter on isospin sensitive observables in intermediate-energy heavy-ion collisions with the ImQMD05 code, a modified version of the quantum molecular dynamics model. At incident velocities above the Fermi velocity, we find that the density dependence of the symmetry potential plays a more important role on the double neutron-to-proton ratio DR(n/p) and the isospin transport ratio Ri than the in-medium nucleon-nucleon cross sections, provided that the latter are constrained to a fixed total NN collision rate. We also explore both DR(n/p) and Ri as a function of the impact parameter. Since the copious production of intermediate mass fragments is a distinguishing feature of intermediate-energy heavy-ion collisions, we examine the isospin transport ratios constructed from different groups of fragments. We find that the values of the isospin transport ratios for projectile rapidity fragments with Z⩾20 are greater than those constructed from the entire projectile rapidity source. We believe experimental investigations of this phenomenon can be performed. These may provide significant tests of fragmentation time scales predicted by ImQMD calculations.

  16. Impact of Oxidative Stress on Hemorheological Parameters in Patients with Acute Poisonings by Psychopharmacological Agents

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    M. V. Belova

    2010-01-01

    Full Text Available Objective: to evaluate the impact of oxidative stress intensity on hemorheological parameters in acute poisonings by psychopharmacological agents. Subjects and methods. The blood values of lipid peroxidation (LPO and the antioxidant system (AOS, and hemorheological parameters were determined in 196 patients with acute poisoning by psychopharmacological agents. Results. Mild poisoning was accompanied by a moderate rise in peroxidation processes, by compensated antioxidant activity, and by a decrease in hemorheological parameters. In moderate poisoning, and severe one in particular, there was an increase in the LPO/AOS imbalance attended by increases in the viscosity characteristics of blood and plasma and in the aggregation activity of platelets and red blood cells. Conclusion. As the intensity of oxidative stress increases, there are more severe impairments in blood viscosity and aggregation properties, the leading mechanism of which is damage to blood cells due to higher stiffness of their membranes and to plasma release of large-disperse molecules under the action of an excess of LPO products. Key words: oxidative stress, acute poisonings, hemorheology.

  17. The impact of calculation on the value of thermodynamic parameters of copper adsorption on poplar sawdust

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    Brdar Mirjana M.

    2011-01-01

    Full Text Available The adsorption of Cu(II onto poplar sawdust as an adsorbent is analyzed. The experimental data were fitted by the Langmuir isotherm using four linearized forms at the isotherm along with the original one. The least squares regression method was applied. Using the obtained Langmuir constants by each at methods, the enthalpy, entropy and Gibbs free energy at adsoption were calculated. A comparison of the used linear and non-linear regression methods in view at the goodness of the fit is presented. The coefficient of correlation was adopted as a criterionn to select the best method. The impact of the choice at regression model on the resulting estimates of the thermodynamic parameters is discussed. The best fit of the experimental data is obtained by the nonlinear regression. Thus, it is recommended to use the Langmuir parameters calculated by the nonlinear regression for estimating the thermodynamic parameters of adsorptin. The differences in the values obtained by different models are not so large to change the basic conclusion that the adsorption of copper ions on poplar sawdust is a spontaneous endothermic process i.e. that tested adsorbent has an affinity for copper ions.

  18. Impact of interplanetary shock on parameters of plasma turbulence in the Earth's magnetosheath

    Science.gov (United States)

    Rakhmanova, L. S.; Riazantseva, M. O.; Borodkova, N. L.; Sapunova, O. V.; Zastenker, G. N.

    2017-11-01

    Data from the BMSW spectrometer, which measures the ion flux value and sometimes plasma parameters with a time resolution of 31 ms, allow the study of the parameters of turbulence of the solar wind and magnetosheath plasma on kinetic scales. In this work, the frequency spectra of the ion flux fluctuations before and after recording the interplanetary shock front in the Earth's magnetosheath are compared based on these data. It is shown that, in contrast to the solar wind, where the exponential decay of the spectrum often occurs after the shock front on the kinetic scales, no such phenomenon is observed in the magnetosheath: the spectrum on these scales can be approximated by a power function in all the cases considered. In half of these cases, the spectrum slope on the kinetic scales does not change during the interplanetary shock propagation. The results indicate a weak impact of interplanetary shock waves on the parameters of the plasma turbulence. In addition, it is shown that an interplanetary shock does not change the level of intermittency of the ion flux in the magnetosheath at both low and high level before the front.

  19. Evaluation of risk impact of changes to Completion Times addressing model and parameter uncertainties

    International Nuclear Information System (INIS)

    Martorell, S.; Martón, I.; Villamizar, M.; Sánchez, A.I.; Carlos, S.

    2014-01-01

    This paper presents an approach and an example of application for the evaluation of risk impact of changes to Completion Times within the License Basis of a Nuclear Power Plant based on the use of the Probabilistic Risk Assessment addressing identification, treatment and analysis of uncertainties in an integrated manner. It allows full development of a three tired approach (Tier 1–3) following the principles of the risk-informed decision-making accounting for uncertainties as proposed by many regulators. Completion Time is the maximum outage time a safety related equipment is allowed to be down, e.g. for corrective maintenance, which is established within the Limiting Conditions for Operation included into Technical Specifications for operation of a Nuclear Power Plant. The case study focuses on a Completion Time change of the Accumulators System of a Nuclear Power Plant using a level 1 PRA. It focuses on several sources of model and parameter uncertainties. The results obtained show the risk impact of the proposed CT change including both types of epistemic uncertainties is small as compared with current safety goals of concern to Tier 1. However, what concerns to Tier 2 and 3, the results obtained show how the use of some traditional and uncertainty importance measures helps in identifying high risky configurations that should be avoided in NPP technical specifications no matter the duration of CT (Tier 2), and other configurations that could take part of a configuration risk management program (Tier 3). - Highlights: • New approach for evaluation of risk impact of changes to Completion Times. • Integrated treatment and analysis of model and parameter uncertainties. • PSA based application to support risk-informed decision-making. • Measures of importance for identification of risky configurations. • Management of important safety issues to accomplish safety goals

  20. Evaluation of Impact of Voiding Posture on Uroflowmetry Parameters in Men

    Directory of Open Access Journals (Sweden)

    Apul Goel

    2017-08-01

    Full Text Available Purpose: To evaluate the impact of voiding position on uroflowmetry parameters and to assess its potential clinical implications. Materials and Methods: We conducted a prospective study from 2013 to 2015 and included men between 18 and 77 years old who were either healthy volunteers with an International Prostate Symptom Score (IPSS ≤7 or men with benign prostate enlargement that were on alpha-blocker medication and had an IPSS <10. Participants underwent uroflowmetry and post-void residual urine (PVRU measurements twice, once in a sitting position and once in a standing position. The participants were divided into 4 groups based on age (35 years or younger, 36 to 50 years, 51 to 60 years, and older than 60 years. Results: A total of 740 men with a mean age of 40.35 years were evaluated. There was no significant difference in uroflowmetry parameters until the age of 50 years between the voiding positions. However, in those older than 50 years, PVRU volume was significantly lower in the sitting position than the standing position, whereas voiding time was significantly higher in the sitting position than the standing position. Other uroflowmetry parameters, including maximal and average urine flow rates, were non-significant. Conclusions: The voiding position plays an important role in the uroflowmetry parameters of elderly men. Voiding in the sitting position was found to be optimal for elderly men, whereas the role of the voiding position in healthy young men could not be determined. More research is needed to further study this issue.

  1. THE IMPACT OF TOXIC HEAVY METALS ON THE HEMATOLOGICAL PARAMETERS IN COMMON CARP (CYPRINUS CARPIO L.

    Directory of Open Access Journals (Sweden)

    R. Vinodhini ، M. Narayanan

    2009-01-01

    Full Text Available The aim of the present investigation was to determine the effect of heavy metal pollutants such as cadmium, chromium, nickel and lead in aquatic system on common carp (Cyprinus carpio L. by using a set of biochemical parameters. The experimental group of fish was exposed to a sublethal concentration of 5 mg/L of combined (Cd+Pb+Cr+Ni metal solution containing 1.25 mg/L of each metal ion (1/10th of LC 50/48 h for a period of 32 days. The results indicated that the values of the hemoglobin were in the range of 55.30±1.20 g/L to 74.55±1.33 g/L (p<0.001 and the packed cell volume was in the range of 26.72±0.26% to 30.68±0.43% (p<0.01. Concentrations of red blood cells, blood glucose and total cholesterol were significantly elevated. The level of serum iron and copper was increased. The results showed the decreased activity of vitamin C during chronic exposure to toxic heavy metals, which indicates the presence of reactive oxygen species–induced peroxidation. The study suggested that the presence of toxic heavy metals in aquatic environment has strong influence on the hematological parameters in the fresh water fish common carp (Cyprinus carpio L..

  2. Impact of spiral separator geometrical parameters on the density separation of various fine-grained materials

    Directory of Open Access Journals (Sweden)

    Szpyrka Jan

    2017-01-01

    Full Text Available The study aims at the assessment of the impact of geometrical parameters of spiral separators on the efficiency of density separation of fine-grained materials. Experiments were carried out on three spiral separators: Krebs 2.85, Reichert LD-4 and Reichert LG-7. Three materials were used for the tests: raw coal, coal waste and mix of sand and magnetite as the model material. Results of raw coal and coal waste upgrading showed that density separation was most efficient in Reichert LD-4 spiral. This is due to the fact that this device had the highest amount of coils, height of sluice as well as was equipped with additional dense product collector and additional water sluice for transport water. The lower slope of sluice and larger height made separation even more efficient. Analysis of separation of model material, that is the mix of sand and magnetite, showed that in this case the existence of additional water sluice does not have an impact on product separation and best results were obtained in the Reichert LG-7 spiral separator. The shape and width of sluices did not have a significant impact on the separation process.

  3. The impact of obesity in the kinematic parameters of gait in young women

    Directory of Open Access Journals (Sweden)

    Silva-Hamu TCD

    2013-06-01

    Full Text Available Tânia Cristina Dias da Silva-Hamu,1 Cibelle Kayenne Martins Roberto Formiga,1 Flávia Martins Gervásio,1 Darlan Martins Ribeiro,2 Gustavo Christofoletti,3 Jônatas de França Barros4 1Physical Therapy Department of the State University of Goiás, Goiânia, Goiás, ²Dr Henrique Santillo Readaptation and Rehabilitation Center, Goiânia, Goiás, 3Physical Therapy Department of the Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, 4Department of Physical Education of the Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil Background: The prevalence of obesity is increasing in the population, particularly in women. Obesity has an impact on the musculoskeletal system, leading to knee and ankle overexertion, difficulty with balance, and functional disability. The aim of this study was to identify changes in kinematic parameters of gait in obese young women. Methods: A case-control study with 24 obese women (mean age 35.20 ± 9.9 years and mean body mass index of 31.85 ± 2.94 kg/m² and 24 eutrophic women (mean age of 36.33 ± 11.14 and mean body mass index of 21.82 ± 1.58 kg/m². The gait of women was evaluated by the system Vicon Motus® 9.2. The linear parameters of speed, cadence, right and left step, and stride lengths were studied, as well as the angular parameters of knee and ankle. Results: There was a decrease in linear gait parameters (P < 0.001, speed, cadence, right and left step, and stride lengths. In regard to the angular parameters of the knee and ankle, there were also differences between the analyses (P < 0.001. At the knee joint, obese women have delayed onset of the second wave of flexion, exacerbating such movement in order to compensate. In regard to the ankle, both groups showed curves of normal plantar flexion and dorsiflexion, but there was a delay in the path graph in the ankle of obese women indicating a reduced range of motion and possible over-exertion of the pretibial

  4. Small-signal modeling with direct parameter extraction for impact ionization effect in high-electron-mobility transistors

    Energy Technology Data Exchange (ETDEWEB)

    Guan, He; Lv, Hongliang; Guo, Hui, E-mail: hguan@stu.xidian.edu.cn; Zhang, Yuming [Key Laboratory of Wide Band-Gap Semiconductor Materials and Devices, School of Microelectronics, Xidian University, Xi' an 710071 (China)

    2015-11-21

    Impact ionization affects the radio-frequency (RF) behavior of high-electron-mobility transistors (HEMTs), which have narrow-bandgap semiconductor channels, and this necessitates complex parameter extraction procedures for HEMT modeling. In this paper, an enhanced small-signal equivalent circuit model is developed to investigate the impact ionization, and an improved method is presented in detail for direct extraction of intrinsic parameters using two-step measurements in low-frequency and high-frequency regimes. The practicability of the enhanced model and the proposed direct parameter extraction method are verified by comparing the simulated S-parameters with published experimental data from an InAs/AlSb HEMT operating over a wide frequency range. The results demonstrate that the enhanced model with optimal intrinsic parameter values that were obtained by the direct extraction approach can effectively characterize the effects of impact ionization on the RF performance of HEMTs.

  5. Impact of Recession on the Parameters of Quality of Regional Centres and their Attractiveness

    Directory of Open Access Journals (Sweden)

    Samo Drobne

    2013-06-01

    Full Text Available This paper explores the findings regarding the impact of recession that began in 2008 in Slovenia to the chosen parameters of quality of regional centres, which are reflected in their attractiveness. We wanted to test the assumption of the impact of recession to the attractiveness of regional centres to both internal migration and commuting flows. To this end, an adjusted gravity spatial interaction model was developed by evaluating regression coefficients. We analysedthe impacts of population size, distance, employment, gross personal income, municipality revenue per capita, average price per square metre of apartments and houses, and age structure in the municipality pertaining to the decision to potentially migrate or commute related to the migration and choice of workplace in the regional centre. The impact of the recession was analysed by comparing the estimations of regression coefficients before the recession (2007 and duringthe recession (2011. It is shown that during the recession, internal migrations to regional centres increased considerably, while commuting to regional centres did not change significantly. We alsoshowed that during the recession, the impact of the distance to the decision to migrate to regional centres slightly increased, while the impact of the distance to the decision to commute did not changesignificantly. Notably, during the crisis the impact of municipality revenue per capita in the regional centre to the analysed flows changed the most: during the recession, the decision to migrate and/orcommute to 'more prosperous' regional centres is made more easily.In the future, it is to be expected that local self-governments will make more effort to consider how to attract taxpayers to their local community and hence enrich the community, while the analysis of theseparameters will become more significant for the individual levels of the local self-government. Gravity models, such as the one used here, include different

  6. Influence of Experimental Parameters Using the Dip-Coating Method on the Barrier Performance of Hybrid Sol-Gel Coatings in Strong Alkaline Environments

    Directory of Open Access Journals (Sweden)

    Rita B. Figueira

    2015-04-01

    Full Text Available Previous studies have shown that the barrier effect and the performance of organic-inorganic hybrid (OIH sol-gel coatings are highly dependent on the coating deposition method as well as on the processing conditions. However, studies on how the coating deposition method influences the barrier properties in alkaline environments are scarce. The aim of this experimental research was to study the influence of experimental parameters using the dip-coating method on the barrier performance of an OIH sol-gel coating in contact with simulated concrete pore solutions (SCPS. The influence of residence time (Rt, a curing step between each dip step and the number of layers of sol-gel OIH films deposited on hot-dip galvanized steel to prevent corrosion in highly alkaline environments was studied. The barrier performance of these OIH sol-gel coatings, named U(400, was assessed in the first instants of contact with SCPS, using electrochemical impedance spectroscopy and potentiodynamic methods. The durability and stability of the OIH coatings in SCPS was monitored during eight days by macrocell current density. The morphological characterization of the surface was performed by Scanning Electronic Microscopy before and after exposure to SCPS. Glow Discharge Optical Emission Spectroscopy was used to investigate the thickness of the U(400 sol-gel coatings as a function of the number of layers deposited with and without Rt in the coatings thickness.

  7. Impact of systematic errors on DVH parameters of different OAR and target volumes in Intracavitary Brachytherapy (ICBT)

    International Nuclear Information System (INIS)

    Mourya, Ankur; Singh, Gaganpreet; Kumar, Vivek; Oinam, Arun S.

    2016-01-01

    Aim of this study is to analyze the impact of systematic errors on DVH parameters of different OAR and Target volumes in intracavitary brachytherapy (ICBT). To quantify the changes in dose-volume histogram parameters due to systematic errors in applicator reconstruction of brachytherapy planning, known errors in catheter reconstructions have to be introduced in applicator coordinate system

  8. Additional components of risk assessment and their impact on the probability parameter

    Directory of Open Access Journals (Sweden)

    Piotr Saja

    2017-04-01

    Full Text Available The article raises the issue of risk assessment and its impact on the quality and safety of work. During the assessment of the turning lathe position additional components associated with the jobs personalization were taken into account. Paragraph 2 item 7 of the Regulation of the Minister of Laborr and Social Policy of 26 September 1997 on general safety regulations defines occupational risk as the likelihood of an adverse event. The authors drew attention to the reality of the accident, which sometimes depends on the predisposition of the employee. It turns out that a correct estimation of the probability of occurrence of the accident to be able to react in a timely way seems extremely important.. This parameter will be assessed more accurately if we take into account a number of additional components resulting from the characteristics of the employee. The results of the personalized assessment of risk may allow appropriate planning of corrective and preventive actions.

  9. Impact of Building Design Parameters on Thermal Energy Flexibility in a Low-Energy Building

    DEFF Research Database (Denmark)

    Sarran, Lucile; Foteinaki, Kyriaki; Gianniou, Panagiota

    appears to have the largest impact on thermal flexibility. The importance of window design, namely the size, U-value and orientation, is underlined due to its critical influence on solar gains and heat losses. It is eventually observed that thermal mass has a secondary influence on the evaluated......This work focuses on demand-side management potential for the heating grid in residential buildings. The possibility to increase the flexibility provided to the heat network through specific building design is investigated. The role of different parts of the building structure on thermal...... flexibility is assessed through a parameter variation on a building model. Different building designs are subjected to heat cut-offs, and flexibility is evaluated with respect to comfort preservation and heating power peak creation. Under the conditions of this study, the thermal transmittance of the envelope...

  10. Impact parameter dependence of inner-shell vacancy production in fast ion--atom collisions

    International Nuclear Information System (INIS)

    Randall, R.R.

    1975-01-01

    The impact parameter dependence of the probability for production of K x rays has been measured for oxygen projectiles on copper, chlorine projectiles on aluminum, titanium and copper, and carbon and fluorine projectiles on argon at scaled velocities near 0.5. The O + Cu data was taken at incident energies of 1.56, 1.88 and 2.69 MeV/amu for the O bombardment of thin Cu foils. The Cl ions had incident energies of 0.6 and 0.85 MeV/amu upon thin foils of Al, Ti, and Cu. A thin Ar gas target was used for 1.58 MeV/amu C and F beams, permitting measurements to be made for charge-pure C 4+ , C 6+ , F 5+ and F 9+ projectiles. Cu, Cl and Ar K x rays were observed with a Si(Li) detector and scattered particles were counted using a masked surface-barrier detector. Comparison of the shapes of the measured probability curves with predictions of the semiclassical Coulomb approximation (SCA) shows adequate agreement for the O + Cu system. For the higher ratio of projectile to target nuclear charge (Z 1 /Z 2 ) of the Cl + Al, Ti, Cu and C, F + Ar systems, the SCA and Brinkman--Kramers (BK) model for charge transfer fail to predict the measured curves. In particular, the SCA and BK fail to account for large vacancy production probabilities at large impact parameters (larger than the Slater-screened Bohr radii of the K electrons). Further, the dependence of the shapes of the measured curves on the charge state of the incident projectile is pronounced for the cases having the larger Z 1 /Z 2 values. Alternative models are discussed in an attempt to account for the observed behavior

  11. Impact of long-term and short-term therapies on seminal parameters

    Directory of Open Access Journals (Sweden)

    Jlenia Elia

    2013-04-01

    Full Text Available Aim: The aim of this work was: i to evaluate the prevalence of male partners of subfertile couples being treated with long/short term therapies for non andrological diseases; ii to study their seminal profile for the possible effects of their treatments on spermatogenesis and/or epididymal maturation. Methods: The study group was made up of 723 subjects, aged between 25 and 47 years. Semen analysis was performed according to World Health Organization (WHO guidelines (1999. The Superimposed Image Analysis System (SIAS, which is based on the computerized superimposition of spermatozoa images, was used to assess sperm motility parameters. Results: The prevalence of subjects taking pharmacological treatments was 22.7% (164/723. The prevalence was 3.7% (27/723 for the Short-Term Group and 18.9% (137/723 for the Long-Term Group. The subjects of each group were also subdivided into subgroups according to the treatments being received. Regarding the seminal profile, we did not observe a significant difference between the Long-Term, Short-Term or the Control Group. However, regarding the subgroups, we found a significant decrease in sperm number and progressive motility percentage in the subjects receiving treatment with antihypertensive drugs compared with the other subgroups and the Control Group. Conclusions: In the management of infertile couples, the potential negative impact on seminal parameters of any drugs being taken as Long-Term Therapy should be considered. The pathogenic mechanism needs to be clarified.

  12. The impacts of source structure on geodetic parameters demonstrated by the radio source 3C371

    Science.gov (United States)

    Xu, Ming H.; Heinkelmann, Robert; Anderson, James M.; Mora-Diaz, Julian; Karbon, Maria; Schuh, Harald; Wang, Guang L.

    2017-07-01

    Closure quantities measured by very-long-baseline interferometry (VLBI) observations are independent of instrumental and propagation instabilities and antenna gain factors, but are sensitive to source structure. A new method is proposed to calculate a structure index based on the median values of closure quantities rather than the brightness distribution of a source. The results are comparable to structure indices based on imaging observations at other epochs and demonstrate the flexibility of deriving structure indices from exactly the same observations as used for geodetic analysis and without imaging analysis. A three-component model for the structure of source 3C371 is developed by model-fitting closure phases. It provides a real case of tracing how the structure effect identified by closure phases in the same observations as the delay observables affects the geodetic analysis, and investigating which geodetic parameters are corrupted to what extent by the structure effect. Using the resulting structure correction based on the three-component model of source 3C371, two solutions, with and without correcting the structure effect, are made. With corrections, the overall rms of this source is reduced by 1 ps, and the impacts of the structure effect introduced by this single source are up to 1.4 mm on station positions and up to 4.4 microarcseconds on Earth orientation parameters. This study is considered as a starting point for handling the source structure effect on geodetic VLBI from geodetic sessions themselves.

  13. Impact of selected parameters on the development of boiling and flow resistance in the minichannel

    Directory of Open Access Journals (Sweden)

    Piasecka Magdalena

    2015-01-01

    Full Text Available The paper presents results of flow boiling in a rectangular minichannel 1 mm deep, 40 mm wide and 360 mm long. The heating element for FC-72 flowing in the minichannel was the thin alloy foil designated as Haynes-230. There was a microstructure on the side of the foil which comes into contact with fluid in the channel. Two types of microstructured heating surfaces: one with micro-recesses distributed evenly and another with mini-recesses distributed unevenly were used. The paper compares the impact of the microstructured heating surface and minichannel positions on the development of boiling and two phase flow pressure drop. The local heat transfer coefficients and flow resistance obtained in experiment using three positions of the minichannel, e.g.: 0°, 90° and 180° were analyzed. The study of the selected thermal and flow parameters (mass flux density and inlet pressure, geometric parameters and type of cooling liquid on the boiling heat transfer was also conducted. The most important factor turned out to be channel orientation. Application of the enhanced heating surface caused the increase of the heat transfer coefficient from several to several tens per cent, in relation to the plain surface.

  14. Impact of HIV Infection and Zidovudine Therapy on RBC Parameters and Urine Methylmalonic Acid Levels

    Directory of Open Access Journals (Sweden)

    Adewumi Adediran

    2016-01-01

    Full Text Available Background. Anaemia is a common complication of human immunodeficiency virus (HIV infection. The aim of this study was to investigate the impact of HIV infection and zidovudine on red blood cells (RBC parameters and urine methylmalonic acid (UMMA levels in patients with HIV infection. Material and Methods. A cross-sectional study involving 114 subjects, 94 of which are HIV-infected nonanaemic and 20 HIV negative subjects (Cg as control. Full blood count parameters and urine methylmalonic acid (UMMA level of each subject were determined. Associations were determined by Chi-square test and logistic regression statistics where appropriate. Results. Subjects on zidovudine-based ART had mean MCV (93 fL higher than that of control group (82.9 fL and ART-naïve (85.9 fL subjects and the highest mean RDW. Mean UMMA level, which reflects vitamin B12 level status, was high in all HIV-infected groups but was significantly higher in ART-naïve subjects than in ART-experienced subjects. Conclusion. Although non-zidovudine therapy may be associated with macrocytosis (MCV > 95 fL, zidovudine therapy and ART naivety may not. Suboptimal level of vitamin B12 as measured by high UMMA though highest in ART-naïve subjects was common in all HIV-infected subjects.

  15. Impact parameter dependence of linear momentum transfer and the role of two-body dissipation mechanisms in heavy ion collisions around the Fermi energy

    Science.gov (United States)

    Piattelli, P.; Santonocito, D.; Blumenfeld, Y.; Suomijärvi, T.; Agodi, C.; Alamanos, N.; Alba, R.; Auger, F.; Bellia, G.; Chomaz, Ph.; Colonna, M.; Coniglione, R.; del Zoppo, A.; Finocchiaro, P.; Frascaria, N.; Gillibert, A.; Le Faou, J. H.; Loukachine, K.; Maiolino, C.; Migneco, E.; Roynette, J. C.; Sapienza, P.; Scarpaci, J. A.

    1998-12-01

    High energy -rays ( MeV) have been measured in coincidence with heavy residues emitted in reactions induced by a 37 MeV/u Ar beam on a Mo target.The -ray yield increases strongly with increasing linear momentum transfer indicating the importance of two-body collisions in the transfer mechanism. The high energy -ray multiplicity has been used to correlate the linear momentum transfer to the impact parameter. This correlation is compared to dynamical BNV simulations to show the essential role of two body nucleon-nucleon collisions at these bombarding energies.

  16. Observation of an impact-parameter window in low-velocity ionizing collisions of Ne+ on Ne proceeding through quasimolecular states

    International Nuclear Information System (INIS)

    Abdallah, M.A.; Cocke, C.L.; Stoeckli, M.; Wolff, W.; Wolf, H.E.

    1998-01-01

    Target ionization in collisions of singly charged Ne + ions with Ne has been investigated at projectile velocities from 0.25 to 0.55 a.u. using electron and recoil momentum imaging techniques. The momentum distributions of the ejected electrons were found to carry a distinct signature strongly suggesting that ionization is taking place by successive promotions through molecular orbitals. The observed recoil transverse momentum distributions are donut-shaped, indicating that single ionization is confined to a well-defined impact-parameter window. copyright 1998 The American Physical Society

  17. Impacts of reduced pH from ocean CO{sub 2} disposal: Sensitivity of zooplankton mortality to model parameters

    Energy Technology Data Exchange (ETDEWEB)

    Adams, E.E.; Caulfield, J.A.; Herzog, H.J.; Auerbach, D.I. [Massachusetts Inst. of Tech., Cambridge, MA (United States)

    1998-07-01

    The authors have developed a methodology to quantify mortality suffered by marine zooplankton passing through a CO{sub 2}-enriched sea water plume. Here the authors explore model sensitivity to some of the more important biological, physical and engineering design parameters, with particular reference to CO{sub 2} injection as a buoyant droplet plume. Uncertainty in the dose-response relationship, e.g. caused by the use of data for surface organisms, will affect predicted values of total mortality by less than a factor of two for a single point discharge from 10 standard (500 MWe) coal-fired values of total mortality by less than a factor of two for a single point discharge from 10 standard 500 MWe coal-fired electric power plants and a factor of five for a single point discharge from one standard plant. The most important design variable is the number of physically separated discharge points (diffuser ports or groups of ports) used to disperse the CO{sub 2}. Predicted mortality drops to zero as the number of discharge points per standard plants exceeds two. Finally the most important physical parameters are ambient current speed and turbulent diffusivity. As with the dose-response data, most physical oceanographic measurements have been conducted near the ocean surface. Model sensitivity suggests that a factor of 2.5 reduction in current speed or a factor of 3 reduction in ambient diffusivity, relative to the base case, would require that the number of discharge points per standard plant increase from 2 to 12 in order to avoid mortality. Thus, impacts can be strongly site-specific, and additional oceanographic measurements are needed at depths appropriate for CO{sub 2} sequestration. Nonetheless, it should be easy to design an environmentally conservative multi-point discharge system that can disperse CO{sub 2} as a droplet plume without significant mortality, even under adverse environmental conditions.

  18. Parameter study for child injury mitigation in near-side impacts through FE simulations.

    Science.gov (United States)

    Andersson, Marianne; Pipkorn, Bengt; Lövsund, Per

    2012-01-01

    The objective of this study is to investigate the effects of crash-related car parameters on head and chest injury measures for 3- and 12-year-old children in near-side impacts. The evaluation was made using a model of a complete passenger car that was impacted laterally by a barrier. The car model was validated in 2 crash conditions: the Insurance Institute for Highway Safety (IIHS) and the US New Car Assessment Program (NCAP) side impact tests. The Small Side Impact Dummy (SID-IIs) and the human body model 3 (HBM3) (Total HUman Model for Safety [THUMS] 3-year-old) finite element models were used for the parametric investigation (HBM3 on a booster). The car parameters were as follows: vehicle mass, side impact structure stiffness, a head air bag, a thorax-pelvis air bag, and a seat belt with pretensioner. The studied dependent variables were as follows: resultant head linear acceleration, resultant head rotational acceleration, chest viscous criterion, rib deflection, and relative velocity at head impact. The chest measurements were only considered for the SID-IIs. The head air bag had the greatest effect on the head measurements for both of the occupant models. On average, it reduced the peak head linear acceleration by 54 g for the HBM3 and 78 g for the SID-IIs. The seat belt had the second greatest effect on the head measurements; the peak head linear accelerations were reduced on average by 39 g (HBM3) and 44 g (SID-IIs). The high stiffness side structure increased the SID-IIs' head acceleration, whereas it had marginal effect on the HBM3. The vehicle mass had a marginal effect on SID-IIs' head accelerations, whereas the lower vehicle mass caused 18 g higher head acceleration for HBM3 and the greatest rotational acceleration. The thorax-pelvis air bag, vehicle mass, and seat belt pretensioner affected the chest measurements the most. The presence of a thorax-pelvis air bag, high vehicle mass, and a seat belt pretensioner all reduced the chest viscous criterion

  19. Methodologies, models and parameters for environmental, impact assessment of hazardous and radioactive contaminants

    International Nuclear Information System (INIS)

    Aguero, A.; Cancio, D.; Garcia-Olivares, A.; Romero, L.; Pinedo, P.; Robles, B.; Rodriguez, J.; Simon, I.; Suanez, A.

    2003-01-01

    An Environmental Impact Assessment Methodology to assess the impact arising from contaminants present in hazardous and radioactive wastes has been developed. Taking into account of the background information on legislation, waste categories and contaminants inventory, and disposal, recycling and waste treatment options, an Environmental Impact Assessment Methodology (MEIA) is proposed. This is applicable to (i) several types of solid wastes (hazardous, radioactive and mixed wastes; (ii) several management options (recycling and temporal and final storage (in shallow and deep disposal)), (iii) several levels of data availability. Conceptual and mathematical models and software tools needed for the application of the MEIA have been developed. Bearing in mind that this is a complex process, both the models and tools have to be developed following an iterative approaches, involving refinement of the models and go as to better correspond the described system. The selection of suitable parameters for the models is based on information derived from field and laboratory measurements and experiments, nd then applying a data elicitation protocol.. It is shown an application performed for a hypothetical shallow radioactive waste disposal facility (test case), with all the steps of the MEIA applied sequentially. In addition, the methodology is applied to an actual cases of waste management for hazardous wastes from the coal fuel cycle, demonstrating several possibilities for application of the MEIA from a practical perspective. The experience obtained in the development of the work shows that the use of the MEIA for the assessment of management options for hazardous and radioactive wastes gives important advantages, simplifying the execution of the assessment, its tracability and the dissemination of methodology assessment results to to other interested parties. (Author)

  20. Looking for very low tectonic deformation in GNSS time series impacted by strong hydrological signal in the Okavango Delta, Botswana

    Science.gov (United States)

    Pastier, Anne-Morwenn; Dauteuil, Olivier; Murray-Hudson, Michael; Makati, Kaelo; Moreau, Frédérique; Crave, Alain; Longuevergne, Laurent; Walpersdorf, Andrea

    2017-04-01

    Located in northern Botswana, the Okavango Delta is a vast wetland, fed from the Angolan highlands and constrained by a half-graben in the Kalahari depression. Since the 70's, the Okavango graben is usually considered as the terminus of the East African Rift System. But a recent geodetic study showed there has been no extension on the tectonic structure over the past 5 years, and recent geophysical studies began to call this hypothesis into question. The deformation in the area could instead be related to far-field deformation accommodation due to the motion of the Kalahari craton relative to the rest of the Nubian plate and to the opening of the Rift Valley. Getting to the vertical deformation isn't trivial. The GNSS time series show a strong annual deformation of the ground surface (3 cm of amplitude). On the vertical component, this periodic signal is so strong that it hides the tectonic long-term deformation, while this information would give a crucial insight on the geodynamic process at play. This periodic signal is related to the seasonal loading of water due to the rainy season. This hypothesis is corroborated by the modeling of the surface deformation based on the GRACE satellites data, interpreted as the variation of groundwater amount. In the Okavango Delta, the peak of water level isn't paced with the local precipitations, but is driven by a flood pulse coming from the Angolan Highlands. The migration of this massive water body isn't visible at first order in GRACE data. Yet, local precipitations are supposed to undergo too much evapotranspiration to be significant in the hydrological balance. Thus this later water body isn't supposed to produce a mass anomaly in GRACE time series. This paradox could highlight a relationship not yet defined between groundwater and local rainfall. The wide spatial resolution of GRACE data (about 300 km) doesn't allow a modeling accurate enough to give access to the slow tectonic deformation, nor to determine the

  1. Strong Impact of an Axial Ligand on the Absorption by Chlorophyll a and b Pigments Determined by Gas-Phase Ion Spectroscopy Experiments

    DEFF Research Database (Denmark)

    Kjaer, Christina; Stockett, Mark H.; Pedersen, Bjarke Møller

    2016-01-01

    The microenvironments in photosynthetic proteins affect the absorption by chlorophyll (Chl) pigments. It is, however, a challenge to disentangle the impact on the transition energies of different perturbations, for example, the global electrostatics of the protein (nonbonded environmental effects......), exciton coupling between Chl's, conformational variations, and binding of an axial ligand to the magnesium center. This is needed to distinguish between the two most commonly proposed mechanisms for energy transport in photosynthetic proteins, relying on either weakly or strongly coupled pigments. Here...

  2. Bacterial surface appendages strongly impact nanomechanical and electrokinetic properties of Escherichia coli cells subjected to osmotic stress.

    Directory of Open Access Journals (Sweden)

    Grégory Francius

    Full Text Available The physicochemical properties and dynamics of bacterial envelope, play a major role in bacterial activity. In this study, the morphological, nanomechanical and electrohydrodynamic properties of Escherichia coli K-12 mutant cells were thoroughly investigated as a function of bulk medium ionic strength using atomic force microscopy (AFM and electrokinetics (electrophoresis. Bacteria were differing according to genetic alterations controlling the production of different surface appendages (short and rigid Ag43 adhesins, longer and more flexible type 1 fimbriae and F pilus. From the analysis of the spatially resolved force curves, it is shown that cells elasticity and turgor pressure are not only depending on bulk salt concentration but also on the presence/absence and nature of surface appendage. In 1 mM KNO(3, cells without appendages or cells surrounded by Ag43 exhibit large Young moduli and turgor pressures (∼700-900 kPa and ∼100-300 kPa respectively. Under similar ionic strength condition, a dramatic ∼50% to ∼70% decrease of these nanomechanical parameters was evidenced for cells with appendages. Qualitatively, such dependence of nanomechanical behavior on surface organization remains when increasing medium salt content to 100 mM, even though, quantitatively, differences are marked to a much smaller extent. Additionally, for a given surface appendage, the magnitude of the nanomechanical parameters decreases significantly when increasing bulk salt concentration. This effect is ascribed to a bacterial exoosmotic water loss resulting in a combined contraction of bacterial cytoplasm together with an electrostatically-driven shrinkage of the surface appendages. The former process is demonstrated upon AFM analysis, while the latter, inaccessible upon AFM imaging, is inferred from electrophoretic data interpreted according to advanced soft particle electrokinetic theory. Altogether, AFM and electrokinetic results clearly demonstrate the

  3. Improving metabolic parameters of antipsychotic child treatment (IMPACT) study: rationale, design, and methods.

    Science.gov (United States)

    Reeves, Gloria M; Keeton, Courtney; Correll, Christoph U; Johnson, Jacqueline L; Hamer, Robert M; Sikich, Linmarie; Hazzard, Lindsey; Alderman, Cheryl; Scheer, Abigail; Mabe, Micah; Kapoor, Sandeep; Sheridan, Eva; Borner, Irmgard; Bussell, Kristin; Pirmohamed, Sara; Bethea, Terrence C; Chekuri, Raja; Gottfried, Rhoda; Reinblatt, Shauna P; Santana, Erin; Riddle, Mark A

    2013-08-15

    Youth with serious mental illness may experience improved psychiatric stability with second generation antipsychotic (SGA) medication treatment, but unfortunately may also experience unhealthy weight gain adverse events. Research on weight loss strategies for youth who require ongoing antipsychotic treatment is quite limited. The purpose of this paper is to present the design, methods, and rationale of the Improving Metabolic Parameters in Antipsychotic Child Treatment (IMPACT) study, a federally funded, randomized trial comparing two pharmacologic strategies against a control condition to manage SGA-related weight gain. The design and methodology considerations of the IMPACT trial are described and embedded in a description of health risks associated with antipsychotic-related weight gain and the limitations of currently available research. The IMPACT study is a 4-site, six month, randomized, open-label, clinical trial of overweight/obese youth ages 8-19 years with pediatric schizophrenia-spectrum and bipolar-spectrum disorders, psychotic or non-psychotic major depressive disorder, or irritability associated with autistic disorder. Youth who have experienced clinically significant weight gain during antipsychotic treatment in the past 3 years are randomized to either (1) switch antipsychotic plus healthy lifestyle education (HLE); (2) add metformin plus HLE; or (3) HLE with no medication change. The primary aim is to compare weight change (body mass index z-scores) for each pharmacologic intervention with the control condition. Key secondary assessments include percentage body fat, insulin resistance, lipid profile, psychiatric symptom stability (monitored independently by the pharmacotherapist and a blinded evaluator), and all-cause and specific cause discontinuation. This study is ongoing, and the targeted sample size is 132 youth. Antipsychotic-related weight gain is an important public health issue for youth requiring ongoing antipsychotic treatment to

  4. The Impact of Strong Climate Change on Inter-state Balancing in a Fully-renewable Simplified European Electricity System

    Science.gov (United States)

    Wohland, Jan; Witthaut, Dirk

    2017-04-01

    Electricity systems with a high penetration of renewables are strongly affected by weather patterns. Due to the variability of the climate system, a substantial fraction of energy supply needs to be provided by dispatchable power plants even if the consumption is on average balanced by renewables (e.g. Rodriguez et al. [2014]). In an interconnected system like the European electricity grid, benefits can arise from balancing generation mismatches spatially as long as overproduction in one region coincides with lack of generation in another region. These benefits might change as the climate changes and we thus investigate alterations of correlations between wind timeseries and Backup energy requirements. Our analysis is based on a five member model-ensemble from the EUROCORDEX initiative and we focus on onshore wind energy. We use the highest temporal (3h) and spatial (0.11°) resolution available to capture the intermittent and spatially diverse nature of renewable generation. In view of inter-model spread and other uncertainties, we use the strong climate change scenario rcp8.5 in order to obtain a high signal-to-noise ratio. We argue that rcp8.5 is best suited to reveal interesting interactions between climate change and renewable electricity system despite the fact that is in contradiction to the UNFCCC temperature goals (e.g. Schleussner et al. [2016]). We report spatially inhomogeneous alterations of correlations. In particular, we find increasing correlations between central and northern European states and decreasing correlations at the south-western and south-eastern margins of Europe. This hints to a lowering of balancing potentials within central and northern Europe due to climate change. A possible explanation might be associated to polar amplification and increasing frequencies of blocking events (Coumou [2015]). Moreover, we compute wind energy generation using a single-turbine model and a semi-random deployment procedure as developed in Monforti et al

  5. Strong Impact of Chronic Cerebral Hypoperfusion on Neurovascular Unit, Cerebrovascular Remodeling, and Neurovascular Trophic Coupling in Alzheimer's Disease Model Mouse.

    Science.gov (United States)

    Shang, Jingwei; Yamashita, Toru; Zhai, Yun; Nakano, Yumiko; Morihara, Ryuta; Fukui, Yusuke; Hishikawa, Nozomi; Ohta, Yasuyuki; Abe, Koji

    2016-03-05

    Although chronic cerebral hypoperfusion (CCH) may affect Alzheimer's disease (AD) pathogenesis, the mechanism remains elusive. In the present study, we investigated the role of CCH on an AD mouse model in neurovascular unit, cerebrovascular remodeling, and neurovascular trophic coupling. Moreover, examined protective effect of galantamine. Alzheimer's disease transgenic mice (APP23) were subjected to bilateral common carotid arteries stenosis with ameroid constrictors for slowly progressive cerebral hypoperfusion. CCH exacerbated neuronal loss and decrease of α7 subunit of nicotinic acetylcholine receptors (α7-nAChRs) expression in hippocampus and thalamus at 12 months. Meanwhile, CCH greatly induced advanced glycation end products expression, and blood-brain barrier leakage through observing IgG and MMP9 expressions. Furthermore, a significant number of dramatic enlarged cerebral vessels with remodeling, BDNF/TrkB decreased in neurovascular trophic coupling. The present study demonstrated that CCH strongly enhanced primary AD pathology including neurodegeneration, neurovascular unit disruption, cerebrovascular remodeling and neurovascular trophic coupling damage in AD mice, and that galantamine treatment greatly ameliorated such neuropathologic abnormalities.

  6. Impact of UVA exposure on psychological parameters and circulating serotonin and melatonin

    Directory of Open Access Journals (Sweden)

    Sauermann Kirsten

    2002-04-01

    Full Text Available Abstract Background People tend to feel better after exposure to ultraviolet (UV radiation. This study was performed to investigate the impact of UVA exposure on psychological and neuroendocrine parameters. Methods Fifty-three volunteers were separated into 42 individuals who had UVA exposure and 11 individuals who had no UVA exposure. The UVA-exposed volunteers had irradiation sessions six times in a three-week period. All volunteers completed two questionnaires at baseline (T1 and at the end of the study (T3. For the determination of serotonin and melatonin serum levels of all volunteers blood samples were collected at baseline (T1, after the first UVA exposure (T2, and at the end of the study after the sixth exposure (T3. Results UVA-exposed volunteers felt significantly more balanced, less nervous, more strengthened, and more satisfied with their appearance at T3. By contrast, the controls did not show significant changes of psychological parameters. In comparison to T1 and T3, serum serotonin was significantly higher and the serum melatonin was significantly lower for the volunteers exposed to UVA at T2. Both, for exposed and non-exposed volunteers serotonin and melatonin levels did not significantly differ at T1 and T3. Conclusions It remains obscure, whether the exposure to UVA or other components of the treatment were responsible for the psychological benefits observed. The changes of circulating neuroendocrine mediators found after UVA exposure at T2 may be due to an UVA-induced effect via a cutaneous pathway. Nevertheless, the positive psychological effects observed in our study cannot be attributed to circulating serotonin or melatonin.

  7. Impact of Endogenous and Exogenous Interferences on Clinical Chemistry Parameters Measured on Blood Gas Analyzers.

    Science.gov (United States)

    Grieme, Caleb V; Voss, Dena R; Davis, Scott R; Krasowski, Matthew D

    2017-03-01

    The prevalence of hemolysis, icterus, and lipemia (HIL) was determined for residual whole blood specimens analyzed for clinical chemistry parameters on blood gas analyzers. The frequency and potential impact of exogenous interference from iodide, salicylate, and thiocyanate (metabolite of sodium nitroprusside) on analysis of whole blood chloride was also assessed. Over an approximately two month period at an academic medical center, indices for HIL were determined on Roche cobas c502 analyzers for 1,986 residual whole blood specimens that had been previously analyzed for clinical chemistry parameters on Radiometer ABL90 FLEX blood gas analyzers. To examine exogenous interferences, retrospective analysis was performed over multiple years to ascertain whether patient samples analyzed for whole blood chloride were potentially affected by interference from iodide, salicylate, or thiocyanate. Some degree of hemolysis (defined as hemolysis index of greater than 60) was present in 9.7% of the whole blood specimens. Increasing rates of hemolysis were associated with higher whole blood potassium concentrations. Nearly 60% of specimens with potassium concentrations between 6.0 and 6.9 mEq/L had hemolysis indices of 100 or greater, and 75% of specimens with a potassium concentration of 7.0 mEq/L or greater were severely hemolyzed (hemolysis index of 300 or greater). In contrast to the hemolysis results, icterus and lipemia were determined to have minimal impact on patient results. For the exogenous interferences, we did not identify any patient samples where elevated salicylate levels or pharmaceutical iodide administration overlapped with whole blood chloride analysis (out of 75,887 and 169,229 total chloride measurements, respectively). We did, however, find that for patients receiving nitroprusside therapy in the inpatient setting, whole blood chloride concentrations were significantly higher during nitroprusside therapy [106.7 +/- 6.2 mEq/L (mean, SD)] compared to before

  8. Impact of line parameter database and continuum absorption on GOSAT TIR methane retrieval

    Science.gov (United States)

    Yamada, A.; Saitoh, N.; Nonogaki, R.; Imasu, R.; Shiomi, K.; Kuze, A.

    2017-12-01

    The current methane retrieval algorithm (V1) at wavenumber range from 1210 cm-1 to 1360 cm-1 including CH4 ν 4 band from the thermal infrared (TIR) band of Thermal and Near-infrared Sensor for Carbon Observation Fourier Transform Spectrometer (TANSO-FTS) onboard Greenhouse Gases Observing Satellite (GOSAT) uses LBLRTM V12.1 with AER V3.1 line database and MT CKD 2.5.2 continuum absorption model to calculate optical depth. Since line parameter databases have been updated and the continuum absorption may have large uncertainty, the purpose of this study is to assess the impact on {CH}4 retrieval from the choice of line parameter databases and the uncertainty of continuum absorption. We retrieved {CH}4 profiles with replacement of line parameter database from AER V3.1 to AER v1.0, HITRAN 2004, HITRAN 2008, AER V3.2, or HITRAN 2012 (Rothman et al. 2005, 2009, and 2013. Clough et al., 2005), we assumed 10% larger continuum absorption coefficients and 50% larger temperature dependent coefficient of continuum absorption based on the report by Paynter and Ramaswamy (2014). We compared the retrieved CH4 with the HIPPO CH4 observation (Wofsy et al., 2012). The difference from HIPPO observation of AER V3.2 was the smallest and 24.1 ± 45.9 ppbv. The differences of AER V1.0, HITRAN 2004, HITRAN 2008, and HITRAN 2012 were 35.6 ± 46.5 ppbv, 37.6 ± 46.3 ppbv, 32.1 ± 46.1 ppbv, and 35.2 ± 46.0 ppbv, respectively. Maximum {CH}4 retrieval differences were -0.4 ppbv at the layer of 314 hPa when we used 10% larger absorption coefficients of {H}2O foreign continuum. Comparing AER V3.2 case to HITRAN 2008 case, the line coupling effect reduced difference by 8.0 ppbv. Line coupling effects were important for GOSAT TIR {CH}4 retrieval. Effects from the uncertainty of continuum absorption were negligible small for GOSAT TIR CH4 retrieval.

  9. Evaluation of the impact of higher-order energy enhancement characteristics of solitons in strongly dispersion-managed optical fibers

    International Nuclear Information System (INIS)

    Diaz-Otero, Francisco J.; Guillán-Lorenzo, Omar; Pedrosa-Rodríguez, Laura

    2017-01-01

    Highlights: • Empirical model describing the pulse energy enhancement required to obtain stable pulses to higher-order polynomial equations • An improvement in the accuracy is obtained through the addition of a new quartic addend dependent on the map strength. • This conclusion is validated through a comparison in a commercial DM soliton submarine network. • The error in the interaction distance for two adjacent pulses in the same channel is of the same order as the energy error - Abstract: We study the propagation properties of nonlinear pulses with periodic evolution in a dispersion-managed transmission link by means of a variational approach. We fit the energy enhancement required for stable propagation of a single soliton in a prototypical commercial link to a polynomial approximation that describes the dependence of the energy on the map strength of the normalized unit cell. We present an improvement of a relatively old and essential result, namely, the dependence of the energy-enhancement factor of dispersion-management solitons with the square of the map strength of the fiber link. We find that adding additional corrections to the conventional quadratic formula up to the fourth order results in an improvement in the accuracy of the description of the numerical results obtained with the variational approximation. Even a small error in the energy is found to introduce large deviations in the pulse parameters during its evolution. The error in the evaluation of the interaction distance between two adjacent time division multiplexed pulses propagating in the same channel in a prototypical submarine link is of the same order as the error in the energy.

  10. Tiny cause with huge impact: polar instability through strong magneto-electric-elastic coupling in bulk EuTiO3.

    Science.gov (United States)

    Reuvekamp, Patrick; Caslin, Kevin; Guguchia, Zurab; Keller, Hugo; Kremer, Reinhard K; Simon, Arndt; Köhler, Jürgen; Bussmann-Holder, Annette

    2015-07-08

    EuTiO3 exhibits strong magneto-electric coupling at the onset of antiferromagnetic order below TN = 5.7 K. The dielectric permittivity drops at TN by 7% and recovers to normal values with increasing magnetic field. This effect is shown to stem from tiny lattice effects as seen in magnetostriction data which directly affect the soft optic mode and its polarizability coordinate. By combining experimental results with theory we show that marginal changes in the lattice parameter of the order of 0.01% have a more than 1000% effect on the transverse optic soft mode of ETO and thus easily induce a ferroelectric instability.

  11. On the impact of the elastic-plastic flow upon the process of destruction of the solenoid in a super strong pulsed magnetic field

    Science.gov (United States)

    Krivosheev, S. I.; Magazinov, S. G.; Alekseev, D. I.

    2018-01-01

    At interaction of super strong magnetic fields with a solenoid material, a specific mode of the material flow forms. To describe this process, magnetohydrodynamic approximation is traditionally used. The formation of plastic shock-waves in material in a rapidly increasing pressure of 100 GPa/μs, can significantly alter the distribution of the physical parameters in the medium and affect the flow modes. In this paper, an analysis of supporting results of numerical simulations in comparison with available experimental data is presented.

  12. Dayside ionosphere of Titan: Impact on calculated plasma densities due to variations in the model parameters

    Science.gov (United States)

    Mukundan, Vrinda; Bhardwaj, Anil

    2018-01-01

    A one dimensional photochemical model for the dayside ionosphere of Titan has been developed for calculating the density profiles of ions and electrons under steady state photochemical equilibrium condition. We concentrated on the T40 flyby of Cassini orbiter and used the in-situ measurements from instruments onboard Cassini as input to the model. An energy deposition model is employed for calculating the attenuated photon flux and photoelectron flux at different altitudes in Titan's ionosphere. We used the Analytical Yield Spectrum approach for calculating the photoelectron fluxes. Volume production rates of major primary ions, like, N2+, N+ , CH4+, CH3+, etc due to photon and photoelectron impact are calculated and used as input to the model. The modeled profiles are compared with the Cassini Ion Neutral Mass Spectrometer (INMS) and Langmuir Probe (LP) measurements. The calculated electron density is higher than the observation by a factor of 2 to 3 around the peak. We studied the impact of different model parameters, viz. photoelectron flux, ion production rates, electron temperature, dissociative recombination rate coefficients, neutral densities of minor species, and solar flux on the calculated electron density to understand the possible reasons for this discrepancy. Recent studies have shown that there is an overestimation in the modeled photoelectron flux and N2+ ion production rates which may contribute towards this disagreement. But decreasing the photoelectron flux (by a factor of 3) and N2+ ion production rate (by a factor of 2) decreases the electron density only by 10 to 20%. Reduction in the measured electron temperature by a factor of 5 provides a good agreement between the modeled and observed electron density. The change in HCN and NH3 densities affects the calculated densities of the major ions (HCNH+ , C2H5+, and CH5+); however the overall impact on electron density is not appreciable ( < 20%). Even though increasing the dissociative

  13. Impact of extraction parameters on the recovery of lipolytic activity from fermented babassu cake.

    Directory of Open Access Journals (Sweden)

    Jaqueline N Silva

    Full Text Available Enzyme extraction from solid matrix is as important step in solid-state fermentation to obtain soluble enzymes for further immobilization and application in biocatalysis. A method for the recovery of a pool of lipases from Penicillium simplicissimum produced by solid-state fermentation was developed. For lipase recovery different extraction solution was used and phosphate buffer containing Tween 80 and NaCl showed the best results, yielding lipase activity of 85.7 U/g and 65.7 U/g, respectively. The parameters with great impacts on enzyme extraction detected by the Plackett-Burman analysis were studied by Central Composite Rotatable experimental designs where a quadratic model was built showing maximum predicted lipase activity (160 U/g at 25°C, Tween 80 0.5% (w/v, pH 8.0 and extraction solution 7 mL/g, maintaining constant buffer molarity of 0.1 M and 200 rpm. After the optimization process a 2.5 fold increase in lipase activity in the crude extract was obtained, comparing the intial value (64 U/g with the experimental design (160 U/g, thus improving the overall productivity of the process.

  14. THE IMPACT OF SELECTED TECHNOLOGICAL AND MATERIAL PARAMETERS ON THE STRENGTH OF ADHESIVE STEEL SHEETS JOINTS

    Directory of Open Access Journals (Sweden)

    Anna Rudawska

    2017-06-01

    Full Text Available The following paper analyses selected problems regarding the impact of technological parameters and type of adherend material on the strength of adhesive-bonded steel sheet joints. The subject of the test was a single-lap adhesive joint of S235JR steel sheet. Joints were formed on two types of substrates: with or without corrosion products on the surface. The surface of steel sheet adherends was pre-treated with three cleaning solutions: acetone, Wiko industrial degreasing agent and Cortanin F anti-corrosion agent, depend-ing on the state of the surface. Adhesive joints were formed with Epidian 53/ET/100:15 epoxy adhesive. The formed joints were subjected to one of three ageing variants: 14 days, two months and 3 months, which were followed by destructive testing to determine the shear strength of joints. The analysis of results ob-tained in tests indicates that the strength performance of adhesive joints of corrosion-free adherends was characterised by higher values than in corroded steel sheets, regardless of ageing time.

  15. Assessment of impact of acoustic and nonacoustic parameters on performance and well-being

    Science.gov (United States)

    Mellert, Volker; Weber, Reinhard; Nocke, Christian

    2004-05-01

    It is of interest to estimate the influence of the environment in a specific work place area on the performance and well-being of people. Investigations have been carried out for the cabin environment of an airplane and for class rooms. Acoustics is only one issue of a variety of environmental factors, therefore the combined impact of temperature, humidity, air quality, lighting, vibration, etc. on human perception is the subject of psychophysical research. Methods for the objective assessment of subjective impressions have been developed for applications in acoustics for a long time, e.g., for concert hall acoustics, noise evaluation, and sound design. The methodology relies on questionnaires, measurement of acoustic parameters, ear-related signal processing and analysis, and on correlation of the physical input with subjective output. Methodology and results are presented from measurements of noise and vibration, temperature and humidity in aircraft simulators, and of reverberation, coloring, and lighting in a primary school, and of the environmental perception. [The work includes research with M. Klatte, A. Schick from the Psychology Department of Oldenburg University, and M. Meis from Hoerzentrum Oldenburg GmbH and with the European Project HEACE (for partners see www.heace.org).

  16. Impact of droplet evaporation rate on resulting in vitro performance parameters of pressurized metered dose inhalers.

    Science.gov (United States)

    Sheth, Poonam; Grimes, Matthew R; Stein, Stephen W; Myrdal, Paul B

    2017-08-07

    Pressurized metered dose inhalers (pMDIs) are widely used for the treatment of pulmonary diseases. The overall efficiency of pMDI drug delivery may be defined by in vitro parameters such as the amount of drug that deposits on the model throat and the proportion of the emitted dose that has particles that are sufficiently small to deposit in the lung (i.e., fine particle fraction, FPF). The study presented examines product performance of ten solution pMDI formulations containing a variety of cosolvents with diverse chemical characteristics by cascade impaction with three inlets (USP induction port, Alberta Idealized Throat, and a large volume chamber). Through the data generated in support of this study, it was demonstrated that throat deposition, cascade impactor deposition, FPF, and mass median aerodynamic diameter of solution pMDIs depend on the concentration and vapor pressure of the cosolvent, and the selection of model throat. Theoretical droplet lifetimes were calculated for each formulation using a discrete two-stage evaporation process model and it was determined that the droplet lifetime is highly correlated to throat deposition and FPF indicating that evaporation kinetics significantly influences pMDI drug delivery. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Adhesion molecules expression in CLL: Potential impact on clinical and hematological parameters.

    Science.gov (United States)

    Kamel, Azza M; El-Sharkawy, Nahla M; Osman, Randa A; Abd El-Fattah, Eman K; El-Noshokaty, Essam; Abd El-Hamid, Thoraya; Kandeel, Eman Z

    2016-03-01

    B-cell chronic lymphocytic leukemia (CLL) is marked by the accumulation of CD5+ B lymphocytes within the blood, bone marrow (BM), and secondary lymphoid tissues. Abnormalities in the expression and function of cell adhesion molecules may account for the patterns of intra-nodal growth and hematogenous spread of the malignant cells. Chemokines and integrin-mediated adhesion and trans-endothelial migration (TEM) are central aspects in trafficking and retention of hematopoietic cells in the BM and lymphoid organs. This work was conducted to study adhesion molecules status in CLL and its potential impact on both hematological and clinical parameters. The study included 78 newly diagnosed CLL patients. Immunophenotyping was performed on peripheral blood using the chronic lymphoid panel. Adhesion molecules (CD11a, CD11b, CD49d, CD49C, CD29 and CD38) were tested using monoclonal antibodies and analyzed by Flow Cytometry. Positive correlation was encountered between adhesion molecules: CD38 with CD49d (r=0.25, p=0.028), CD11a with CD11b, CD49d and CD29 (r=0.394, p=0.001; r=0.441, p=molecules expression in CLL is apparently reflected on the potential migratory behavior of the leukemic cells to different organs. Copyright © 2016 National Cancer Institute, Cairo University. Production and hosting by Elsevier B.V. All rights reserved.

  18. Search for displaced supersymmetry in events with an electron and a muon with large impact parameters.

    Science.gov (United States)

    Khachatryan, V; Sirunyan, A M; Tumasyan, A; Adam, W; Bergauer, T; Dragicevic, M; Erö, J; Friedl, M; Frühwirth, R; Ghete, V M; Hartl, C; Hörmann, N; Hrubec, J; Jeitler, M; Kiesenhofer, W; Knünz, V; Krammer, M; Krätschmer, I; Liko, D; Mikulec, I; Rabady, D; Rahbaran, B; Rohringer, H; Schöfbeck, R; Strauss, J; Taurok, A; Treberer-Treberspurg, W; Waltenberger, W; Wulz, C-E; Mossolov, V; Shumeiko, N; Suarez Gonzalez, J; Alderweireldt, S; Bansal, M; Bansal, S; Cornelis, T; De Wolf, E A; Janssen, X; Knutsson, A; Luyckx, S; Ochesanu, S; Rougny, R; Van De Klundert, M; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Van Spilbeeck, A; Blekman, F; Blyweert, S; D'Hondt, J; Daci, N; Heracleous, N; Keaveney, J; Lowette, S; Maes, M; Olbrechts, A; Python, Q; Strom, D; Tavernier, S; Van Doninck, W; Van Mulders, P; Van Onsem, G P; Villella, I; Caillol, C; Clerbaux, B; De Lentdecker, G; Dobur, D; Favart, L; Gay, A P R; Grebenyuk, A; Léonard, A; Mohammadi, A; Perniè, L; Reis, T; Seva, T; Thomas, L; Vander Velde, C; Vanlaer, P; Wang, J; Zenoni, F; Adler, V; Beernaert, K; Benucci, L; Cimmino, A; Costantini, S; Crucy, S; Dildick, S; Fagot, A; Garcia, G; Mccartin, J; Ocampo Rios, A A; Ryckbosch, D; Salva Diblen, S; Sigamani, M; Strobbe, N; Thyssen, F; Tytgat, M; Yazgan, E; Zaganidis, N; Basegmez, S; Beluffi, C; Bruno, G; Castello, R; Caudron, A; Ceard, L; Da Silveira, G G; Delaere, C; du Pree, T; Favart, D; Forthomme, L; Giammanco, A; Hollar, J; Jafari, A; Jez, P; Komm, M; Lemaitre, V; Nuttens, C; Pagano, D; Perrini, L; Pin, A; Piotrzkowski, K; Popov, A; Quertenmont, L; Selvaggi, M; Vidal Marono, M; Vizan Garcia, J M; Beliy, N; Caebergs, T; Daubie, E; Hammad, G H; Aldá Júnior, W L; Alves, G A; Brito, L; Correa Martins Junior, M; Dos Reis Martins, T; Mora Herrera, C; Pol, M E; Carvalho, W; Chinellato, J; Custódio, A; Da Costa, E M; De Jesus Damiao, D; De Oliveira Martins, C; Fonseca De Souza, S; Malbouisson, H; Matos Figueiredo, D; Mundim, L; Nogima, H; Prado Da Silva, W L; Santaolalla, J; Santoro, A; Sznajder, A; Tonelli Manganote, E J; Vilela Pereira, A; Bernardes, C A; Dogra, S; Fernandez Perez Tomei, T R; Gregores, E M; Mercadante, P G; Novaes, S F; Padula, Sandra S; Aleksandrov, A; Genchev, V; Iaydjiev, P; Marinov, A; Piperov, S; Rodozov, M; Stoykova, S; Sultanov, G; Vutova, M; Dimitrov, A; Glushkov, I; Hadjiiska, R; Kozhuharov, V; Litov, L; Pavlov, B; Petkov, P; Bian, J G; Chen, G M; Chen, H S; Chen, M; Du, R; Jiang, C H; Plestina, R; Romeo, F; Tao, J; Wang, Z; Asawatangtrakuldee, C; Ban, Y; Liu, S; Mao, Y; Qian, S J; Wang, D; Zhang, L; Zou, W; Avila, C; Chaparro Sierra, L F; Florez, C; Gomez, J P; Gomez Moreno, B; Sanabria, J C; Godinovic, N; Lelas, D; Polic, D; Puljak, I; Antunovic, Z; Kovac, M; Brigljevic, V; Kadija, K; Luetic, J; Mekterovic, D; Sudic, L; Attikis, A; Mavromanolakis, G; Mousa, J; Nicolaou, C; Ptochos, F; Razis, P A; Bodlak, M; Finger, M; Finger, M; Assran, Y; Ellithi Kamel, A; Mahmoud, M A; Radi, A; Kadastik, M; Murumaa, M; Raidal, M; Tiko, A; Eerola, P; Fedi, G; Voutilainen, M; Härkönen, J; Karimäki, V; Kinnunen, R; Kortelainen, M J; Lampén, T; Lassila-Perini, K; Lehti, S; Lindén, T; Luukka, P; Mäenpää, T; Peltola, T; Tuominen, E; Tuominiemi, J; Tuovinen, E; Wendland, L; Talvitie, J; Tuuva, T; Besancon, M; Couderc, F; Dejardin, M; Denegri, D; Fabbro, B; Faure, J L; Favaro, C; Ferri, F; Ganjour, S; Givernaud, A; Gras, P; Hamel de Monchenault, G; Jarry, P; Locci, E; Malcles, J; Rander, J; Rosowsky, A; Titov, M; Baffioni, S; Beaudette, F; Busson, P; Charlot, C; Dahms, T; Dalchenko, M; Dobrzynski, L; Filipovic, N; Florent, A; Granier de Cassagnac, R; Mastrolorenzo, L; Miné, P; Mironov, C; Naranjo, I N; Nguyen, M; Ochando, C; Paganini, P; Regnard, S; Salerno, R; Sauvan, J B; Sirois, Y; Veelken, C; Yilmaz, Y; Zabi, A; Agram, J-L; Andrea, J; Aubin, A; Bloch, D; Brom, J-M; Chabert, E C; Collard, C; Conte, E; Fontaine, J-C; Gelé, D; Goerlach, U; Goetzmann, C; Le Bihan, A-C; Van Hove, P; Gadrat, S; Beauceron, S; Beaupere, N; Boudoul, G; Bouvier, E; Brochet, S; Carrillo Montoya, C A; Chasserat, J; Chierici, R; Contardo, D; Depasse, P; El Mamouni, H; Fan, J; Fay, J; Gascon, S; Gouzevitch, M; Ille, B; Kurca, T; Lethuillier, M; Mirabito, L; Perries, S; Ruiz Alvarez, J D; Sabes, D; Sgandurra, L; Sordini, V; Vander Donckt, M; Verdier, P; Viret, S; Xiao, H; Tsamalaidze, Z; Autermann, C; Beranek, S; Bontenackels, M; Edelhoff, M; Feld, L; Hindrichs, O; Klein, K; Ostapchuk, A; Perieanu, A; Raupach, F; Sammet, J; Schael, S; Weber, H; Wittmer, B; Zhukov, V; Ata, M; Brodski, M; Dietz-Laursonn, E; Duchardt, D; Erdmann, M; Fischer, R; Güth, A; Hebbeker, T; Heidemann, C; Hoepfner, K; Klingebiel, D; Knutzen, S; Kreuzer, P; Merschmeyer, M; Meyer, A; Millet, P; Olschewski, M; Padeken, K; Papacz, P; Reithler, H; Schmitz, S A; Sonnenschein, L; Teyssier, D; Thüer, S; Weber, M; Cherepanov, V; Erdogan, Y; Flügge, G; Geenen, H; Geisler, M; Haj Ahmad, W; Heister, A; Hoehle, F; Kargoll, B; Kress, T; Kuessel, Y; Künsken, A; Lingemann, J; Nowack, A; Nugent, I M; 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    2015-02-13

    A search for new long-lived particles decaying to leptons is presented using proton-proton collisions produced by the LHC at √[s]=8  TeV. Data used for the analysis were collected by the CMS detector and correspond to an integrated luminosity of 19.7  fb(-1). Events are selected with an electron and muon with opposite charges that both have transverse impact parameter values between 0.02 and 2 cm. The search has been designed to be sensitive to a wide range of models with nonprompt e-μ final states. Limits are set on the "displaced supersymmetry" model, with pair production of top squarks decaying into an e-μ final state via R-parity-violating interactions. The results are the most restrictive to date on this model, with the most stringent limit being obtained for a top squark lifetime corresponding to cτ=2  cm, excluding masses below 790 GeV at 95% confidence level.

  19. Search for Displaced Supersymmetry in events with an electron and a muon with large impact parameters

    CERN Document Server

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Placakyte, Ringaile; Raspereza, Alexei; Ribeiro Cipriano, Pedro M; Roland, Benoit; Ron, Elias; Sahin, Mehmet Özgür; Salfeld-Nebgen, Jakob; Saxena, Pooja; Schmidt, Ringo; Schoerner-Sadenius, Thomas; Schröder, Matthias; Seitz, Claudia; Spannagel, Simon; Vargas Trevino, Andrea Del Rocio; Walsh, Roberval; Wissing, Christoph; Aldaya Martin, Maria; Blobel, Volker; Centis Vignali, Matteo; Draeger, Arne-Rasmus; Erfle, Joachim; Garutti, Erika; Goebel, Kristin; Görner, Martin; Haller, Johannes; Hoffmann, Malte; Höing, Rebekka Sophie; Kirschenmann, Henning; Klanner, Robert; Kogler, Roman; Lange, Jörn; Lapsien, Tobias; Lenz, Teresa; Marchesini, Ivan; Ott, Jochen; Peiffer, Thomas; Pietsch, Niklas; Poehlsen, Jennifer; Pöhlsen, Thomas; Rathjens, Denis; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Seidel, Markus; Sola, Valentina; Stadie, Hartmut; Steinbrück, Georg; Troendle, Daniel; Usai, Emanuele; Vanelderen, Lukas; Vanhoefer, Annika; Barth, Christian; Baus, Colin; Berger, Joram; Böser, Christian; Butz, Erik; Chwalek, Thorsten; De Boer, Wim; Descroix, Alexis; Dierlamm, Alexander; Feindt, Michael; Frensch, Felix; Giffels, Manuel; Hartmann, Frank; Hauth, Thomas; Husemann, Ulrich; Katkov, Igor; Kornmayer, Andreas; Kuznetsova, Ekaterina; Lobelle Pardo, Patricia; Mozer, Matthias Ulrich; Müller, Thomas; Nürnberg, Andreas; Quast, Gunter; Rabbertz, Klaus; Ratnikov, Fedor; Röcker, Steffen; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Wayand, Stefan; Weiler, Thomas; Wolf, Roger; Anagnostou, Georgios; Daskalakis, Georgios; Geralis, Theodoros; Giakoumopoulou, Viktoria Athina; Kyriakis, Aristotelis; Loukas, Demetrios; Markou, Athanasios; Markou, Christos; Psallidas, Andreas; Topsis-Giotis, Iasonas; Kesisoglou, Stilianos; Panagiotou, Apostolos; Saoulidou, Niki; Stiliaris, Efstathios; Aslanoglou, Xenofon; Evangelou, Ioannis; Flouris, Giannis; Foudas, Costas; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Paradas, Evangelos; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Zsigmond, Anna Julia; Beni, Noemi; Czellar, Sandor; Karancsi, János; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Swain, Sanjay Kumar; Beri, Suman Bala; Bhatnagar, Vipin; Gupta, Ruchi; Bhawandeep, Bhawandeep; Kalsi, Amandeep Kaur; Kaur, Manjit; Kumar, Ramandeep; Mittal, Monika; Nishu, Nishu; Singh, Jasbir; Kumar, Ashok; Kumar, Arun; Ahuja, Sudha; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Kumar, Ajay; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Varun; Banerjee, Sunanda; Bhattacharya, Satyaki; Chatterjee, Kalyanmoy; Dutta, Suchandra; Gomber, Bhawna; Jain, Sandhya; Jain, Shilpi; Khurana, Raman; Modak, Atanu; Mukherjee, Swagata; Roy, Debarati; Sarkar, Subir; Sharan, Manoj; Abdulsalam, Abdulla; Dutta, Dipanwita; Kailas, Swaminathan; Kumar, Vineet; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Topkar, Anita; Aziz, Tariq; Banerjee, Sudeshna; Bhowmik, Sandeep; Chatterjee, Rajdeep Mohan; Dewanjee, Ram Krishna; Dugad, Shashikant; Ganguly, Sanmay; Ghosh, Saranya; Guchait, Monoranjan; Gurtu, Atul; Kole, Gouranga; Kumar, Sanjeev; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Parida, Bibhuti; Sudhakar, Katta; Wickramage, Nadeesha; Bakhshiansohi, Hamed; Behnamian, Hadi; Etesami, Seyed Mohsen; Fahim, Ali; Goldouzian, Reza; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Naseri, Mohsen; Paktinat Mehdiabadi, Saeid; Rezaei Hosseinabadi, Ferdos; Safarzadeh, Batool; Zeinali, Maryam; Felcini, Marta; Grunewald, Martin; Abbrescia, Marcello; Barbone, Lucia; Calabria, Cesare; Chhibra, Simranjit Singh; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Maggi, Giorgio; Maggi, Marcello; My, Salvatore; Nuzzo, Salvatore; Pompili, Alexis; Pugliese, Gabriella; Radogna, Raffaella; Selvaggi, Giovanna; Sharma, Archana; Silvestris, Lucia; Venditti, Rosamaria; Zito, Giuseppe; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Campanini, Renato; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Codispoti, Giuseppe; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Montanari, Alessandro; Navarria, Francesco; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Tosi, Nicolò; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Giordano, Ferdinando; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Gallo, Elisabetta; Gonzi, Sandro; Gori, Valentina; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Fabbri, Franco; Piccolo, Davide; Ferretti, Roberta; Ferro, Fabrizio; Lo Vetere, Maurizio; Robutti, Enrico; Tosi, Silvano; Dinardo, Mauro Emanuele; Fiorendi, Sara; Gennai, Simone; Gerosa, Raffaele; Ghezzi, Alessio; Govoni, Pietro; Lucchini, Marco Toliman; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Martelli, Arabella; Marzocchi, Badder; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Cavallo, Nicola; Di Guida, Salvatore; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Azzi, Patrizia; Bisello, Dario; Branca, Antonio; Carlin, Roberto; Checchia, Paolo; Dall'Osso, Martino; Dorigo, Tommaso; Galanti, Mario; Gasparini, Fabrizio; Gasparini, Ugo; Giubilato, Piero; Gozzelino, Andrea; Kanishchev, Konstantin; Lacaprara, Stefano; Margoni, Martino; Meneguzzo, Anna Teresa; Pazzini, Jacopo; Pegoraro, Matteo; Pozzobon, Nicola; Ronchese, Paolo; Simonetto, Franco; Torassa, Ezio; Tosi, Mia; Triossi, Andrea; Zotto, Pierluigi; Zucchetta, Alberto; Zumerle, Gianni; Gabusi, Michele; Ratti, Sergio P; Re, Valerio; Riccardi, Cristina; Salvini, Paola; Vitulo, Paolo; Biasini, Maurizio; Bilei, Gian Mario; Ciangottini, Diego; Fanò, Livio; Lariccia, Paolo; Mantovani, Giancarlo; Menichelli, Mauro; Saha, Anirban; Santocchia, Attilio; Spiezia, Aniello; Androsov, Konstantin; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; Ciocci, Maria Agnese; Dell'Orso, Roberto; Donato, Silvio; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Grippo, Maria Teresa; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Moon, Chang-Seong; Palla, Fabrizio; Rizzi, Andrea; Savoy-Navarro, Aurore; Serban, Alin Titus; Spagnolo, Paolo; Squillacioti, Paola; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Vernieri, Caterina; Barone, Luciano; Cavallari, Francesca; D'imperio, Giulia; Del Re, Daniele; Diemoz, Marcella; Grassi, Marco; Jorda, Clara; Longo, Egidio; Margaroli, Fabrizio; Meridiani, Paolo; Micheli, Francesco; Nourbakhsh, Shervin; Organtini, Giovanni; Paramatti, Riccardo; Rahatlou, Shahram; Rovelli, Chiara; Santanastasio, Francesco; Soffi, Livia; Traczyk, Piotr; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Bellan, Riccardo; Biino, Cristina; Cartiglia, Nicolo; Casasso, Stefano; Costa, Marco; Degano, Alessandro; Demaria, Natale; Finco, Linda; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Ortona, Giacomo; Pacher, Luca; Pastrone, Nadia; Pelliccioni, Mario; Pinna Angioni, Gian Luca; Potenza, Alberto; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Solano, Ada; Staiano, Amedeo; Tamponi, Umberto; Belforte, Stefano; Candelise, Vieri; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; La Licata, Chiara; Marone, Matteo; Schizzi, Andrea; Umer, Tomo; Zanetti, Anna; Chang, Sunghyun; Kropivnitskaya, Anna; Nam, Soon-Kwon; Kim, Dong Hee; Kim, Gui Nyun; Kim, Min Suk; Kong, Dae Jung; Lee, Sangeun; Oh, Young Do; Park, Hyangkyu; Sakharov, Alexandre; Son, Dong-Chul; Kim, Tae Jeong; Kim, Jae Yool; Song, Sanghyeon; Choi, Suyong; Gyun, Dooyeon; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Yongsun; Lee, Byounghoon; Lee, Kyong Sei; Park, Sung Keun; Roh, Youn; Choi, Minkyoo; Kim, Ji Hyun; Park, Inkyu; Ryu, Geonmo; Ryu, Min Sang; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Kim, Donghyun; Kwon, Eunhyang; Lee, Jongseok; Seo, Hyunkwan; Yu, Intae; Juodagalvis, Andrius; Komaragiri, Jyothsna Rani; Md Ali, Mohd Adli Bin; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-de La Cruz, Ivan; Hernandez-Almada, Alberto; Lopez-Fernandez, Ricardo; Sánchez Hernández, Alberto; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Pedraza, Isabel; Salazar Ibarguen, Humberto Antonio; Casimiro Linares, Edgar; Morelos Pineda, Antonio; Krofcheck, David; Butler, Philip H; Reucroft, Steve; Ahmad, Ashfaq; Ahmad, Muhammad; Hassan, Qamar; Hoorani, Hafeez R; Khan, Wajid Ali; Khurshid, Taimoor; Shah, Mehar Ali; Shoaib, Muhammad; Bialkowska, Helena; Bluj, Michal; Boimska, Bożena; Frueboes, Tomasz; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Zalewski, Piotr; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Olszewski, Michał; Wolszczak, Weronika; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Lloret Iglesias, Lara; Nguyen, Federico; Rodrigues Antunes, Joao; Seixas, Joao; Varela, Joao; Vischia, Pietro; Afanasiev, Serguei; Bunin, Pavel; Gavrilenko, Mikhail; Golutvin, Igor; Gorbunov, Ilya; Kamenev, Alexey; Karjavin, Vladimir; Konoplyanikov, Viktor; Lanev, Alexander; Malakhov, Alexander; Matveev, Viktor; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Shmatov, Sergey; Skatchkov, Nikolai; Smirnov, Vitaly; Zarubin, Anatoli; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Gavrilov, Vladimir; Lychkovskaya, Natalia; Popov, Vladimir; Pozdnyakov, Ivan; Safronov, Grigory; Semenov, Sergey; Spiridonov, Alexander; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Belyaev, Andrey; Boos, Edouard; Bunichev, Viacheslav; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Lokhtin, Igor; Obraztsov, Stepan; Petrushanko, Sergey; Savrin, Viktor; Snigirev, Alexander; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Kachanov, Vassili; Kalinin, Alexey; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Ekmedzic, Marko; Milosevic, Jovan; Rekovic, Vladimir; Alcaraz Maestre, Juan; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Domínguez Vázquez, Daniel; Escalante Del Valle, Alberto; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Navarro De Martino, Eduardo; Pérez Calero Yzquierdo, Antonio María; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Senghi Soares, Mara; Albajar, Carmen; de Trocóniz, Jorge F; Missiroli, Marino; Moran, Dermot; Brun, Hugues; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Duarte Campderros, Jordi; Fernandez, Marcos; Gomez, Gervasio; Graziano, Alberto; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Piedra Gomez, Jonatan; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Benaglia, Andrea; Bendavid, Joshua; Benhabib, Lamia; Benitez, Jose F; Bernet, Colin; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Bondu, Olivier; Botta, Cristina; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Colafranceschi, Stefano; D'Alfonso, Mariarosaria; D'Enterria, David; Dabrowski, Anne; David Tinoco Mendes, Andre; De Guio, Federico; De Roeck, Albert; De Visscher, Simon; Di Marco, Emanuele; Dobson, Marc; Dordevic, Milos; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Eugster, Jürg; Franzoni, Giovanni; Funk, Wolfgang; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Girone, Maria; Glege, Frank; Guida, Roberto; Gundacker, Stefan; Guthoff, Moritz; Hammer, Josef; Hansen, Magnus; Harris, Philip; Hegeman, Jeroen; Innocente, Vincenzo; Janot, Patrick; Kousouris, Konstantinos; Krajczar, Krisztian; Lecoq, Paul; Lourenco, Carlos; Magini, Nicolo; Malgeri, Luca; Mannelli, Marcello; Marrouche, Jad; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moortgat, Filip; Morovic, Srecko; Mulders, Martijn; Musella, Pasquale; Orsini, Luciano; Pape, Luc; Perez, Emmanuelle; Perrozzi, Luca; Petrilli, Achille; Petrucciani, Giovanni; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Piparo, Danilo; Plagge, Michael; Racz, Attila; Rolandi, Gigi; Rovere, Marco; Sakulin, Hannes; Schäfer, Christoph; Schwick, Christoph; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Steggemann, Jan; Stieger, Benjamin; Stoye, Markus; Takahashi, Yuta; Treille, Daniel; Tsirou, Andromachi; Veres, Gabor Istvan; Wardle, Nicholas; Wöhri, Hermine Katharina; Wollny, Heiner; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; Kotlinski, Danek; Langenegger, Urs; Renker, Dieter; Rohe, Tilman; Bachmair, Felix; Bäni, Lukas; Bianchini, Lorenzo; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Dünser, Marc; Eller, Philipp; Grab, Christoph; Hits, Dmitry; Hoss, Jan; Lustermann, Werner; Mangano, Boris; Marini, Andrea Carlo; Martinez Ruiz del Arbol, Pablo; Masciovecchio, Mario; Meister, Daniel; Mohr, Niklas; Nägeli, Christoph; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pauss, Felicitas; Peruzzi, Marco; Quittnat, Milena; Rebane, Liis; Rossini, Marco; Starodumov, Andrei; Takahashi, Maiko; Theofilatos, Konstantinos; Wallny, Rainer; Weber, Hannsjoerg Artur; Amsler, Claude; Canelli, Maria Florencia; Chiochia, Vincenzo; De Cosa, Annapaola; Hinzmann, Andreas; Hreus, Tomas; Kilminster, Benjamin; Lange, Clemens; Millan Mejias, Barbara; Ngadiuba, Jennifer; Robmann, Peter; Ronga, Frederic Jean; Taroni, Silvia; Verzetti, Mauro; Yang, Yong; Cardaci, Marco; Chen, Kuan-Hsin; Ferro, Cristina; Kuo, Chia-Ming; Lin, Willis; Lu, Yun-Ju; Volpe, Roberta; Yu, Shin-Shan; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Chen, Po-Hsun; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Kao, Kai-Yi; Lei, Yeong-Jyi; Liu, Yueh-Feng; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Tzeng, Yeng-Ming; Wilken, Rachel; Asavapibhop, Burin; Singh, Gurpreet; Srimanobhas, Norraphat; Suwonjandee, Narumon; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Mehmet; Akin, Ilina Vasileva; Bilin, Bugra; Bilmis, Selcuk; Gamsizkan, Halil; Karapinar, Guler; Ocalan, Kadir; Sekmen, Sezen; Surat, Ugur Emrah; Yalvac, Metin; Zeyrek, Mehmet; Gülmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Cankocak, Kerem; Vardarlı, Fuat Ilkehan; Levchuk, Leonid; Sorokin, Pavel; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Jacob, Jeson; Kreczko, Lukasz; Lucas, Chris; Meng, Zhaoxia; Newbold, Dave M; Paramesvaran, Sudarshan; Poll, Anthony; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Olaiya, Emmanuel; Petyt, David; Shepherd-Themistocleous, Claire; Thea, Alessandro; Tomalin, Ian R; Womersley, William John; Worm, Steven; Baber, Mark; Bainbridge, Robert; Buchmuller, Oliver; Burton, Darren; Colling, David; Cripps, Nicholas; Cutajar, Michael; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Dunne, Patrick; Ferguson, William; Fulcher, Jonathan; Futyan, David; Gilbert, Andrew; Hall, Geoffrey; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Kenzie, Matthew; Lane, Rebecca; Lucas, Robyn; Lyons, Louis; Magnan, Anne-Marie; Malik, Sarah; Mathias, Bryn; Nash, Jordan; Nikitenko, Alexander; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Raymond, David Mark; Rogerson, Samuel; Rose, Andrew; Seez, Christopher; Sharp, Peter; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Zenz, Seth Conrad; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Martin, William; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Dittmann, Jay; Hatakeyama, Kenichi; Kasmi, Azeddine; Liu, Hongxuan; Scarborough, Tara; Charaf, Otman; Cooper, Seth; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Lawson, Philip; Richardson, Clint; Rohlf, James; St John, Jason; Sulak, Lawrence; Alimena, Juliette; Berry, Edmund; Bhattacharya, Saptaparna; Christopher, Grant; Cutts, David; Demiragli, Zeynep; Dhingra, Nitish; Ferapontov, Alexey; Garabedian, Alex; Heintz, Ulrich; Kukartsev, Gennadiy; Laird, Edward; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Swanson, Joshua; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Erbacher, Robin; Gardner, Michael; Ko, Winston; Lander, Richard; Miceli, Tia; Mulhearn, Michael; Pellett, Dave; Pilot, Justin; Ricci-Tam, Francesca; Searle, Matthew; Shalhout, Shalhout; Smith, John; Squires, Michael; Stolp, Dustin; Tripathi, Mani; Wilbur, Scott; Yohay, Rachel; Cousins, Robert; Everaerts, Pieter; Farrell, Chris; Hauser, Jay; Ignatenko, Mikhail; Rakness, Gregory; Takasugi, Eric; Valuev, Vyacheslav; Weber, Matthias; Burt, Kira; Clare, Robert; Ellison, John Anthony; Gary, J William; Hanson, Gail; Heilman, Jesse; Ivova Rikova, Mirena; Jandir, Pawandeep; Kennedy, Elizabeth; Lacroix, Florent; Long, Owen Rosser; Luthra, Arun; Malberti, Martina; Olmedo Negrete, Manuel; Shrinivas, Amithabh; Sumowidagdo, Suharyo; Wimpenny, Stephen; Andrews, Warren; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; D'Agnolo, Raffaele Tito; Evans, David; Holzner, André; Kelley, Ryan; Klein, Daniel; Lebourgeois, Matthew; Letts, James; Macneill, Ian; Olivito, Dominick; Padhi, Sanjay; Palmer, Christopher; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Sudano, Elizabeth; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Welke, Charles; Würthwein, Frank; Yagil, Avraham; Barge, Derek; Bradmiller-Feld, John; Campagnari, Claudio; Danielson, Thomas; Dishaw, Adam; Dutta, Valentina; Flowers, Kristen; Franco Sevilla, Manuel; Geffert, Paul; George, Christopher; Golf, Frank; Gouskos, Loukas; Incandela, Joe; Justus, Christopher; Mccoll, Nickolas; Richman, Jeffrey; Stuart, David; To, Wing; West, Christopher; Yoo, Jaehyeok; Apresyan, Artur; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Duarte, Javier; Mott, Alexander; Newman, Harvey B; Pena, Cristian; Rogan, Christopher; Spiropulu, Maria; Timciuc, Vladlen; Vlimant, Jean-Roch; Wilkinson, Richard; Xie, Si; Zhu, Ren-Yuan; Azzolini, Virginia; Calamba, Aristotle; Carlson, Benjamin; Ferguson, Thomas; Iiyama, Yutaro; Paulini, Manfred; Russ, James; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Ford, William T; Gaz, Alessandro; Krohn, Michael; Luiggi Lopez, Eduardo; Nauenberg, Uriel; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Alexander, James; Chatterjee, Avishek; Chu, Jennifer; Dittmer, Susan; Eggert, Nicholas; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Skinnari, Louise; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Tucker, Jordan; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Apollinari, Giorgio; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Bolla, Gino; Burkett, Kevin; Butler, Joel Nathan; Cheung, Harry; Chlebana, Frank; Cihangir, Selcuk; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Gottschalk, Erik; Gray, Lindsey; Green, Dan; Grünendahl, Stefan; Gutsche, Oliver; Hanlon, Jim; Hare, Daryl; Harris, Robert M; Hirschauer, James; Hooberman, Benjamin; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Kaadze, Ketino; Klima, Boaz; Kreis, Benjamin; Kwan, Simon; Linacre, Jacob; Lincoln, Don; Lipton, Ron; Liu, Tiehui; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Martinez Outschoorn, Verena Ingrid; Maruyama, Sho; Mason, David; McBride, Patricia; Merkel, Petra; Mishra, Kalanand; Mrenna, Stephen; Musienko, Yuri; Nahn, Steve; Newman-Holmes, Catherine; O'Dell, Vivian; Prokofyev, Oleg; Sexton-Kennedy, Elizabeth; Sharma, Seema; Soha, Aron; Spalding, William J; Spiegel, Leonard; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitbeck, Andrew; Whitmore, Juliana; Yang, Fan; Acosta, Darin; Avery, Paul; Bortignon, Pierluigi; Bourilkov, Dimitri; Carver, Matthew; Cheng, Tongguang; Curry, David; Das, Souvik; De Gruttola, Michele; Di Giovanni, Gian Piero; Field, Richard D; Fisher, Matthew; Furic, Ivan-Kresimir; Hugon, Justin; Konigsberg, Jacobo; Korytov, Andrey; Kypreos, Theodore; Low, Jia Fu; Matchev, Konstantin; Milenovic, Predrag; Mitselmakher, Guenakh; Muniz, Lana; Rinkevicius, Aurelijus; Shchutska, Lesya; Snowball, Matthew; Sperka, David; Yelton, John; Zakaria, Mohammed; Hewamanage, Samantha; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bochenek, Joseph; Diamond, Brendan; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Johnson, Kurtis F; Prosper, Harrison; Veeraraghavan, Venkatesh; Weinberg, Marc; Baarmand, Marc M; Hohlmann, Marcus; Kalakhety, Himali; Yumiceva, Francisco; Adams, Mark Raymond; Apanasevich, Leonard; Bazterra, Victor Eduardo; Berry, Douglas; Betts, Russell Richard; Bucinskaite, Inga; Cavanaugh, Richard; Evdokimov, Olga; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Khalatyan, Samvel; Kurt, Pelin; Moon, Dong Ho; O'Brien, Christine; Silkworth, Christopher; Turner, Paul; Varelas, Nikos; Albayrak, Elif Asli; Bilki, Burak; Clarida, Warren; Dilsiz, Kamuran; Duru, Firdevs; Haytmyradov, Maksat; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Ogul, Hasan; Onel, Yasar; Ozok, Ferhat; Penzo, Aldo; Rahmat, Rahmat; Sen, Sercan; Tan, Ping; Tiras, Emrah; Wetzel, James; Yetkin, Taylan; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bolognesi, Sara; Fehling, David; Gritsan, Andrei; Maksimovic, Petar; Martin, Christopher; Swartz, Morris; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Bruner, Christopher; Kenny III, Raymond Patrick; Malek, Magdalena; Murray, Michael; Noonan, Daniel; Sanders, Stephen; Sekaric, Jadranka; Stringer, Robert; Wang, Quan; Wood, Jeffrey Scott; Chakaberia, Irakli; Ivanov, Andrew; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Saini, Lovedeep Kaur; Shrestha, Shruti; Skhirtladze, Nikoloz; Svintradze, Irakli; Gronberg, Jeffrey; Lange, David; Rebassoo, Finn; Wright, Douglas; Baden, Drew; Belloni, Alberto; Calvert, Brian; Eno, Sarah Catherine; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G; Kolberg, Ted; Lu, Ying; Marionneau, Matthieu; Mignerey, Alice; Pedro, Kevin; Skuja, Andris; Tonjes, Marguerite; Tonwar, Suresh C; Apyan, Aram; Barbieri, Richard; Bauer, Gerry; Busza, Wit; Cali, Ivan Amos; Chan, Matthew; Di Matteo, Leonardo; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Gulhan, Doga; Klute, Markus; Lai, Yue Shi; Lee, Yen-Jie; Levin, Andrew; Luckey, Paul David; Ma, Teng; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Stephans, George; Stöckli, Fabian; Sumorok, Konstanty; Velicanu, Dragos; Veverka, Jan; Wyslouch, Bolek; Yang, Mingming; Zanetti, Marco; Zhukova, Victoria; Dahmes, Bryan; Gude, Alexander; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Pastika, Nathaniel; Rusack, Roger; Singovsky, Alexander; Tambe, Norbert; Turkewitz, Jared; Acosta, John Gabriel; Oliveros, Sandra; Avdeeva, Ekaterina; Bloom, Kenneth; Bose, Suvadeep; Claes, Daniel R; Dominguez, Aaron; Gonzalez Suarez, Rebeca; Keller, Jason; Knowlton, Dan; Kravchenko, Ilya; Lazo-Flores, Jose; Malik, Sudhir; Meier, Frank; Snow, Gregory R; Zvada, Marian; Dolen, James; Godshalk, Andrew; Iashvili, Ia; Kharchilava, Avto; Kumar, Ashish; Rappoccio, Salvatore; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Haley, Joseph; Massironi, Andrea; Morse, David Michael; Nash, David; Orimoto, Toyoko; Trocino, Daniele; Wang, Ren-Jie; Wood, Darien; Zhang, Jinzhong; Hahn, Kristan Allan; Kubik, Andrew; Mucia, Nicholas; Odell, Nathaniel; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael Henry; Stoynev, Stoyan; Sung, Kevin; Velasco, Mayda; Won, Steven; Brinkerhoff, Andrew; Chan, Kwok Ming; Drozdetskiy, Alexey; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kellams, Nathan; Lannon, Kevin; Luo, Wuming; Lynch, Sean; Marinelli, Nancy; Pearson, Tessa; Planer, Michael; Ruchti, Randy; Valls, Nil; Wayne, Mitchell; Wolf, Matthias; Woodard, Anna; Antonelli, Louis; Brinson, Jessica; Bylsma, Ben; Durkin, Lloyd Stanley; Flowers, Sean; Hart, Andrew; Hill, Christopher; Hughes, Richard; Kotov, Khristian; Ling, Ta-Yung; Puigh, Darren; Rodenburg, Marissa; Smith, Geoffrey; Winer, Brian L; Wolfe, Homer; Wulsin, Howard Wells; Driga, Olga; Elmer, Peter; Hebda, Philip; Hunt, Adam; Koay, Sue Ann; Lujan, Paul; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zuranski, Andrzej; Brownson, Eric; Mendez, Hector; Ramirez Vargas, Juan Eduardo; Barnes, Virgil E; Benedetti, Daniele; Bortoletto, Daniela; De Mattia, Marco; Gutay, Laszlo; Hu, Zhen; Jha, Manoj; Jones, Matthew; Jung, Kurt; Kress, Matthew; Leonardo, Nuno; Lopes Pegna, David; Maroussov, Vassili; Miller, David Harry; Neumeister, Norbert; Radburn-Smith, Benjamin Charles; Shi, Xin; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Wang, Fuqiang; Xie, Wei; Xu, Lingshan; Yoo, Hwi Dong; Zablocki, Jakub; Zheng, Yu; Parashar, Neeti; Stupak, John; Adair, Antony; Akgun, Bora; Ecklund, Karl Matthew; Geurts, Frank JM; Li, Wei; Michlin, Benjamin; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Ferbel, Thomas; Garcia-Bellido, Aran; Goldenzweig, Pablo; Han, Jiyeon; Harel, Amnon; Khukhunaishvili, Aleko; Petrillo, Gianluca; Vishnevskiy, Dmitry; Ciesielski, Robert; Demortier, Luc; Goulianos, Konstantin; Lungu, Gheorghe; Mesropian, Christina; Arora, Sanjay; Barker, Anthony; Chou, John Paul; Contreras-Campana, Christian; Contreras-Campana, Emmanuel; Duggan, Daniel; Ferencek, Dinko; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Kaplan, Steven; Lath, Amitabh; Panwalkar, Shruti; Park, Michael; Patel, Rishi; Salur, Sevil; Schnetzer, Steve; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Thomassen, Peter; Walker, Matthew; Rose, Keith; Spanier, Stefan; York, Andrew; Bouhali, Othmane; Castaneda Hernandez, Alfredo; Eusebi, Ricardo; Flanagan, Will; Gilmore, Jason; Kamon, Teruki; Khotilovich, Vadim; Krutelyov, Vyacheslav; Montalvo, Roy; Osipenkov, Ilya; Pakhotin, Yuriy; Perloff, Alexx; Roe, Jeffrey; Rose, Anthony; Safonov, Alexei; Sakuma, Tai; Suarez, Indara; Tatarinov, Aysen; Akchurin, Nural; Cowden, Christopher; Damgov, Jordan; Dragoiu, Cosmin; Dudero, Phillip Russell; Faulkner, James; Kovitanggoon, Kittikul; Kunori, Shuichi; Lee, Sung Won; Libeiro, Terence; Volobouev, Igor; Appelt, Eric; Delannoy, Andrés G; Greene, Senta; Gurrola, Alfredo; Johns, Willard; Maguire, Charles; Mao, Yaxian; Melo, Andrew; Sharma, Monika; Sheldon, Paul; Snook, Benjamin; Tuo, Shengquan; Velkovska, Julia; Arenton, Michael Wayne; Boutle, Sarah; Cox, Bradley; Francis, Brian; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Li, Hengne; Lin, Chuanzhe; Neu, Christopher; Wood, John; Clarke, Christopher; Harr, Robert; Karchin, Paul Edmund; Kottachchi Kankanamge Don, Chamath; Lamichhane, Pramod; Sturdy, Jared; Belknap, Donald; Carlsmith, Duncan; Cepeda, Maria; Dasu, Sridhara; Dodd, Laura; Duric, Senka; Friis, Evan; Hall-Wilton, Richard; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Lanaro, Armando; Lazaridis, Christos; Levine, Aaron; Loveless, Richard; Mohapatra, Ajit; Ojalvo, Isabel; Perry, Thomas; Pierro, Giuseppe Antonio; Polese, Giovanni; Ross, Ian; Sarangi, Tapas; Savin, Alexander; Smith, Wesley H; Taylor, Devin; Verwilligen, Piet; Vuosalo, Carl; Woods, Nathaniel

    2015-02-13

    A search for new long-lived particles decaying to leptons is presented using proton-proton collisions produced by the LHC at $\\sqrt{s}$ = 8 TeV. Data used for the analysis were collected by the CMS detector and correspond to an integrated luminosity of 19.7 fb$^{-1}$. Events are selected with an electron and a muon that have transverse impact parameter values between 0.02 cm and 2 cm. The search has been designed to be sensitive to a wide range of models with non-prompt e-$\\mu$ final states. Limits are set on the ''displaced supersymmetry'' model, with pair production of top squarks decaying into an e-$\\mu$ final state via R-parity violating interactions. The results are the most restrictive to date on this model, with the most stringent limit being obtained for a top squark lifetime corresponding to $c\\tau$ = 2 cm, excluding masses below 790 GeV at 95% confidence level.

  20. Measuring the Higgs boson parity at a Linear Collider using the tau impact parameter and $\\tau \\to \\rho \

    CERN Document Server

    Desch, Klaus; Worek, M

    2003-01-01

    We demonstrate that a measurement of the impact parameter in one-prong tau decay can be useful for the determination of the Higgs boson parity in the H/A --> tau tau; tau --> rho nu decay chain. We have estimated that for a detection set-up such as TESLA, use of the information from the tau impact parameter can improve the significance of the measurement of the parity of the Standard Model 120 GeV Higgs boson to 4.5 sigma, and in general by factor of about 1.5 with respect to the method where this information is not used. We also show that the variation in the assumption on the precision of the measurement of the impact parameter and/or pi's momenta does not affect the sensitivity of the method. This is because the method remains limited by the type of twofold ambiguity in reconstructing the tau momentum.

  1. Using global variables for impact parameter determination in nucleus-nucleus collisions below 100 MeV/u

    International Nuclear Information System (INIS)

    Peter, J.; Cussol, D.; Bizard, G.; Brou, R.; Louvel, M.; Patry, J.P.; Regimbart, R.; Steckmeyer, J.C.; Sullivan, J.P.; Tamain, B.; Motobayashi, T.; Cassagnou, Y.; Legrain, R.; Hagel, K.; Jin, G.M.; Crema, E.

    1990-04-01

    Several global variables are tested for determining the impact parameter in 4π measurements of charged products. For the system Ar+Al from 25 to 85 MeV/u, simulated reactions are used to study the correlation between the real impact parameter value and the experimentally determined one. Even with an imaginary perfect detector, the total multiplicity and the mid-rapidity charge give a poor correlation. Filtering through the acceptance of an actual detector (Mur+Tonneau at GANIL) provides a poor correlation with the total charge, and an acceptable one with the total perpendicular momentum. The average (mass weighted) parallel velocity V av gives the best correlation and is less sensitive to the incident energy and to the mechanisms used in the simulation. Measurements extending to very forward angles are needed to obtain a good impact parameter sorting. 5 figs

  2. The Source and Impact of Specific Parameters that Enhance Well-Being in Daily Life.

    Science.gov (United States)

    Stewart, William C; Reynolds, Kelly E; Jones, Lydia J; Stewart, Jeanette A; Nelson, Lindsay A

    2016-08-01

    The purpose of this study was to review four parameters (forgiveness, gratitude, hope and empathy) frequently noted when evaluating well-being. We reviewed clinical studies from 1966 to present. We included 63 articles. All four of the parameters were shown to generally improve an individual's well-being. These parameters demonstrated a positive influence within more specific societal issues including improvement in social relationships, delinquent behavior and physical health. These parameters were generally derived from training and religion. This study suggests that these parameters may improve either one of general well-being, pro-social and positive relational behavior and demonstrate positive health effects.

  3. Impacts of fuel formulation and engine operating parameters on the nanostructure and reactivity of diesel soot

    Science.gov (United States)

    Yehliu, Kuen

    This study focuses on the impacts of fuel formulations on the reactivity and nanostructure of diesel soot. A 2.5L, 4-cylinder, turbocharged, common rail, direct injection light-duty diesel engine was used in generating soot samples. The impacts of engine operating modes and the start of combustion on soot reactivity were investigated first. Based on preliminary investigations, a test condition of 2400 rpm and 64 Nm, with single and split injection strategies, was chosen for studying the impacts of fuel formulation on the characteristics of diesel soot. Three test fuels were used: an ultra low sulfur diesel fuel (BP15), a pure soybean methyl-ester (B100), and a synthetic Fischer-Tropsch fuel (FT) produced in a gas-to-liquid process. The start of injection (SOI) and fuel rail pressures were adjusted such that the three test fuels have similar combustion phasing, thereby facilitating comparisons between soots from the different fuels. Soot reactivity was investigated by thermogravimetric analysis (TGA). According to TGA, B100 soot exhibits the fastest oxidation on a mass basis followed by BP15 and FT derived soots in order of apparent rate constant. X-ray photoelectron spectroscopy (XPS) indicates no relation between the surface oxygen content and the soot reactivity. Crystalline information for the soot samples was obtained using X-ray diffraction (XRD). The basal plane diameter obtained from XRD was inversely related to the apparent rate constants for soot oxidation. For comparison, high resolution transmission electron microscopy (HRTEM) provided images of the graphene layers. Quantitative image analysis proceeded by a custom algorithm. B100 derived soot possessed the shortest mean fringe length and greatest mean fringe tortuosity. This suggests soot (nano)structural disorder correlates with a faster oxidation rate. Such results are in agreement with the X-ray analysis, as the observed fringe length is a measure of basal plane diameter. Moreover the relation

  4. Closed form formula for the exchange integrals in the impact-parameter treatment of heavy-particle collisions

    International Nuclear Information System (INIS)

    Kocbach, Ladislav; Liska, Richard

    1994-01-01

    The three-dimensional exchange integrals in the impact-parameter treatment of heavy particle collisions can be transformed to one-dimensional integrals over finite range. The closed form formula for the integrands of these one-dimensional integrals is derived. (Author)

  5. Global variables and impact parameter determination in nucleus-nucleus collisions below 100 MeV/u

    International Nuclear Information System (INIS)

    Peter, J.; Cussol, D.; Bizard, G.; Brou, R.; Louvel, M.; Patry, J.P.; Regimbart, R.; Steckmeyer, J.C.; Sullivan, J.P.; Tamain, B.; Cassagnou, Y.; Legrain, R.; Rosato, E.; Hagel, K.; Jin, G.M.; Crema, E.

    1990-03-01

    Several global variables are tested for determining the impact parameter in 4π measurements of charged products. For the system Ar+Al from 25 to 85 MeV/u, simulated reactions are used to study the correlation between the real impact parameter value and the experimentally determined one. Even with a perfect detector, the total multiplicity and the mid-rapidity charge give a poor correlation. Filtering through the acceptance of an actual detector (Mur+Tonneau at GANIL) provides a poor correlation with the total charge, and an acceptable one with the total perpendicular momentum. The average (mass weighted) parallel velocity V gives the best correlation and is less sensitive to the incident energy and to the mechanisms used in the simulation. Measurements extending to very forward angles are needed to accurately sort events by impact parameter. Real data are used to study the variation of other global variables versus V: they exhibit the expected average trend, with broad fluctuations. The excentricity and flow angle allow the evolution of central reactions with the incident energy to be followed. The proportion of relative motion transformed into energy perpendicular to the beam direction decreases when the incident energy increases; its absolute value, however, doubles from 25 to 65 MeV/u. In experimental studies where good separation between participant (pre-equilibrium) and spectator (equilibrium) particles is wanted in addition to good impact parameter sorting, the projectile mass should be in the range 1.2 - 2.5 times the target mass

  6. Illness perception is a strong parameter on anxiety and depression scores in early-stage breast cancer survivors: a single-center cross-sectional study of Turkish patients.

    Science.gov (United States)

    Kus, Tulay; Aktas, Gokmen; Ekici, Hatice; Elboga, Gulcin; Djamgoz, Sabire

    2017-11-01

    Illness perception has been suggested to have a significant effect on anxiety and depression in cancer patients. In this cross-sectional study, we aimed to evaluate this on Turkish breast cancer patients with follow-up periods up to 12 years. A total of 225 patients (with 6 months to 12 years follow-up) were recruited in this cross-sectional study. The patients were divided into three groups of follow-up: 6 months-2 years, 2-5 years, and >5 years. Beck Depression Inventory, Beck Anxiety Inventory, Duke-University of North Carolina Functional Social Support Questionnaire, and Brief Illness Perception Questionnaire were used to assess the depression, anxiety, functional social support (FSS), and illness perception, respectively. Statistical significance of the associations was analyzed using Spearman correlation, Student's t, Mann-Whitney U, and ANOVA tests. Rates of moderate-severe anxiety and depression scores were not correlated with follow-up period and disease stage, whereas all these parameters were associated significantly with FSS and age. Parameters of illness perception were also not correlated with follow-up period and stage of disease. However, illness perception scores were noticeably better with increments in FSS. Also, the parameters of illness perception were strongly associated with the depression/anxiety score. Illness perception is an important determinant of the depression/anxiety score in Turkish breast cancer patients.

  7. The Chameleonic Behavior of Ionic Liquids and its Impact on the Solubility Parameters Estimation

    DEFF Research Database (Denmark)

    Batista, Marta; Neves, Catarina S; Carvalho, Pedro Jorge

    2011-01-01

    The possibility to develop a solubility parameter scale, with the purpose of predicting the performance and help the selection of ILs, is here evaluated. For the estimation of solubility parameters infinite dilution activity coefficient data is used. The results allowed the identification of a cu...

  8. Impact of errors in experimental parameters on reconstructed breast images using diffuse optical tomography.

    Science.gov (United States)

    Deng, Bin; Lundqvist, Mats; Fang, Qianqian; Carp, Stefan A

    2018-03-01

    Near-infrared diffuse optical tomography (NIR-DOT) is an emerging technology that offers hemoglobin based, functional imaging tumor biomarkers for breast cancer management. The most promising clinical translation opportunities are in the differential diagnosis of malignant vs. benign lesions, and in early response assessment and guidance for neoadjuvant chemotherapy. Accurate quantification of the tissue oxy- and deoxy-hemoglobin concentration across the field of view, as well as repeatability during longitudinal imaging in the context of therapy guidance, are essential for the successful translation of NIR-DOT to clinical practice. The ill-posed and ill-condition nature of the DOT inverse problem makes this technique particularly susceptible to model errors that may occur, for example, when the experimental conditions do not fully match the assumptions built into the image reconstruction process. To evaluate the susceptibility of DOT images to experimental errors that might be encountered in practice for a parallel-plate NIR-DOT system, we simulated 7 different types of errors, each with a range of magnitudes. We generated simulated data by using digital breast phantoms derived from five actual mammograms of healthy female volunteers, to which we added a 1-cm tumor. After applying each of the experimental error types and magnitudes to the simulated measurements, we reconstructed optical images with and without structural prior guidance and assessed the overall error in the total hemoglobin concentrations (HbT) and in the HbT contrast between the lesion and surrounding area vs. the best-case scenarios. It is found that slight in-plane probe misalignment and plate rotation did not result in large quantification errors. However, any out-of-plane probe tilting could result in significant deterioration in lesion contrast. Among the error types investigated in this work, optical images were the least likely to be impacted by breast shape inaccuracies but suffered the

  9. Impact of dengue virus (DENV) co-infection on clinical manifestations, disease severity and laboratory parameters.

    Science.gov (United States)

    Dhanoa, Amreeta; Hassan, Sharifah Syed; Ngim, Chin Fang; Lau, Chun Fatt; Chan, Teik Seng; Adnan, Nur Amelia Azreen; Eng, Wilhelm Wei Han; Gan, Han Ming; Rajasekaram, Ganeswrie

    2016-08-11

    The co-circulation of 4 DENV serotypes in geographically expanding area, has resulted in increasing occurrence of DENV co-infections. However, studies assessing the clinical impact of DENV co-infections have been scarce and have involved small number of patients. This study explores the impact of DENV co-infection on clinical manifestations and laboratory parameters. This retrospective study involved consecutive hospitalized patients with non-structural protein 1 (NS1) antigen positivity during an outbreak (Jan to April 2014). Multiplex RT-PCR was performed directly on NS1 positive serum samples to detect and determine the DENV serotypes. All PCR-positive serum samples were inoculated onto C6/36 cells. Multiplex PCR was repeated on the supernatant of the first blind passage of the serum-infected cells. Random samples of supernatant from the first passage of C6/36 infected cells were subjected to whole genome sequencing. Clinical and laboratory variables were compared between patients with and without DENV co-infections. Of the 290 NS1 positive serum samples, 280 were PCR positive for DENV. Medical notes of 262 patients were available for analysis. All 4 DENV serotypes were identified. Of the 262 patients, forty patients (15.3 %) had DENV co-infections: DENV-1/DENV-2(85 %), DENV-1/DENV-3 (12.5 %) and DENV-2/DENV-3 (2.5 %). Another 222 patients (84.7 %) were infected with single DENV serotype (mono-infection), with DENV- 1 (76.6 %) and DENV- 2 (19.8 %) predominating. Secondary dengue infections occurred in 31.3 % patients. Whole genome sequences of random samples representing DENV-1 and DENV-2 showed heterogeneity amongst the DENVs. Multivariate analysis revealed that pleural effusion and the presence of warning signs were significantly higher in the co-infected group, both in the overall and subgroup analysis. Diarrhoea was negatively associated with co-infection. Additionally, DENV-2 co-infected patients had higher frequency of patients with severe thrombocytopenia

  10. Impact of infiltration parameters and Manning roughness on the advance trajectory and irrigation performance for closed-end furrows

    Directory of Open Access Journals (Sweden)

    Weibo Nie

    2014-09-01

    Full Text Available Evaluation of furrow irrigation systems requires accurate estimation of soil infiltration parameters and Manning roughness, and the impact of variations of those parameters should be considered. The objectives of this paper were to verify the reliability of the infiltration parameters and Manning roughness estimated with SIPAR_ID software, and to analyze the impacts of different combinations between soil infiltration parameters and Manning roughness on the water trajectory and irrigation performance for closed-end furrows. The study consisted of field experiments and numerical simulation. Field experiments using Fuji apple trees were conducted in three villages of the Yangling district in October 2007. Infiltration parameters and Manning roughness were estimated with SIPAR_ID software. The estimated values were input into the WinSRFR software, and the advance trajectory and flow depths in the upstream were simulated on each furrow. The results show that the simulated values with WinSRFR software were in good agreement with measured data. Thus, the infiltration parameters and Manning roughness estimated with SIPAR_ID software were reliable. It was found that the water advance trajectory and the irrigation performance were not sensitive to variations of Manning roughness, but they were very sensitive to the variation of soil infiltration parameters laterally across the field between the furrows. Therefore, the average of Manning roughness on the whole field can be used as a representative value to simulate the advance trajectory and irrigation performance for every furrow. However, during the simulations, the variations of the soil infiltration parameters for different furrows across the field must be taken into account. Otherwise, significant errors can be produced in the simulated water advance trajectory and irrigation performance.

  11. Estimation and impact assessment of input and parameter uncertainty in predicting groundwater flow with a fully distributed model

    Science.gov (United States)

    Touhidul Mustafa, Syed Md.; Nossent, Jiri; Ghysels, Gert; Huysmans, Marijke

    2017-04-01

    Transient numerical groundwater flow models have been used to understand and forecast groundwater flow systems under anthropogenic and climatic effects, but the reliability of the predictions is strongly influenced by different sources of uncertainty. Hence, researchers in hydrological sciences are developing and applying methods for uncertainty quantification. Nevertheless, spatially distributed flow models pose significant challenges for parameter and spatially distributed input estimation and uncertainty quantification. In this study, we present a general and flexible approach for input and parameter estimation and uncertainty analysis of groundwater models. The proposed approach combines a fully distributed groundwater flow model (MODFLOW) with the DiffeRential Evolution Adaptive Metropolis (DREAM) algorithm. To avoid over-parameterization, the uncertainty of the spatially distributed model input has been represented by multipliers. The posterior distributions of these multipliers and the regular model parameters were estimated using DREAM. The proposed methodology has been applied in an overexploited aquifer in Bangladesh where groundwater pumping and recharge data are highly uncertain. The results confirm that input uncertainty does have a considerable effect on the model predictions and parameter distributions. Additionally, our approach also provides a new way to optimize the spatially distributed recharge and pumping data along with the parameter values under uncertain input conditions. It can be concluded from our approach that considering model input uncertainty along with parameter uncertainty is important for obtaining realistic model predictions and a correct estimation of the uncertainty bounds.

  12. [Weight parameters of water quality impact and risk grade determination of water environmental sensitive spots in Jiashan].

    Science.gov (United States)

    Xie, Rong-Rong; Pang, Yong; Zhang, Qian; Chen, Ke; Sun, Ming-Yuan

    2012-07-01

    For the safety of the water environment in Jiashan county in Zhejiang Province, one-dimensional hydrodynamic and water quality models are established based on three large-scale monitoring of hydrology and water quality in Jiashan county, three water environmental sensitive spots including Hongqitang dam Chijia hydrological station and Luxie pond are selected to investigate weight parameters of water quality impact and risk grade determination. Results indicate as follows (1) Internal pollution impact in Jiashan areas was greater than the external, the average weight parameters of internal chemical oxygen demand (COD) pollution is 55.3%, internal ammonia nitrogen (NH(4+)-N) is 67.4%, internal total phosphor (TP) is 63.1%. Non-point pollution impact in Jiashan areas was greater than point pollution impact, the average weight parameters of non-point COD pollutions is 53.7%, non-point NH(4+)-N is 65.9%, non-point TP is 57.8%. (2) The risk of Hongqitang dam and Chijia hydrological station are in the middle risk. The risk of Luxie pond is also in the middle risk in August, and in April and December the risk of Luxie pond is low. The strategic decision will be suggested to guarantee water environment security and social and economic security in the study.

  13. SAC-SMA a priori parameter differences and their impact on distributed hydrologic model simulations

    Science.gov (United States)

    Zhang, Ziya; Koren, Victor; Reed, Seann; Smith, Michael; Zhang, Yu; Moreda, Fekadu; Cosgrove, Brian

    2012-02-01

    SummaryDeriving a priori gridded parameters is an important step in the development and deployment of an operational distributed hydrologic model. Accurate a priori parameters can reduce the manual calibration effort and/or speed up the automatic calibration process, reduce calibration uncertainty, and provide valuable information at ungauged locations. Underpinned by reasonable parameter data sets, distributed hydrologic modeling can help improve water resource and flood and flash flood forecasting capabilities. Initial efforts at the National Weather Service Office of Hydrologic Development (NWS OHD) to derive a priori gridded Sacramento Soil Moisture Accounting (SAC-SMA) model parameters for the conterminous United States (CONUS) were based on a relatively coarse resolution soils property database, the State Soil Geographic Database (STATSGO) (Soil Survey Staff, 2011) and on the assumption of uniform land use and land cover. In an effort to improve the parameters, subsequent work was performed to fully incorporate spatially variable land cover information into the parameter derivation process. Following that, finer-scale soils data (the county-level Soil Survey Geographic Database (SSURGO) ( Soil Survey Staff, 2011a,b), together with the use of variable land cover data, were used to derive a third set of CONUS, a priori gridded parameters. It is anticipated that the second and third parameter sets, which incorporate more physical data, will be more realistic and consistent. Here, we evaluate whether this is actually the case by intercomparing these three sets of a priori parameters along with their associated hydrologic simulations which were generated by applying the National Weather Service Hydrology Laboratory's Research Distributed Hydrologic Model (HL-RDHM) ( Koren et al., 2004) in a continuous fashion with an hourly time step. This model adopts a well-tested conceptual water balance model, SAC-SMA, applied on a regular spatial grid, and links to physically

  14. A benchmark study for different numerical parameters and their impact on the calculated strain levels for a model part door outer

    Science.gov (United States)

    Berger, E.; Brenne, T.; Heath, A.; Hochholdinger, B.; Kassem-Manthey, K.; Keßler, L.; Koch, N.; Kortmann, G.; Kröff, A.; Otto, T.; Steinbeck, G.; Till, E.; Verhoeven, H.; Vu, T.-C.; Wiegand, K.

    2005-08-01

    To increase the accuracy of finite element simulations in daily practice the local German and Austrian Deep Drawing Research Groups of IDDRG founded a special Working Group in year 2000. The main objective of this group was the continuously ongoing study and discussion of numerical / material effects in simulation jobs and to work out possible solutions. As a first theme of this group the intensive study of small die radii and the possibility of detecting material failure in these critical forming positions was selected. The part itself is a fictional body panel outside in which the original door handle of the VW Golf A4 has been constructed, a typical position of possible material necking or rupture in the press shop. All conditions to do a successful simulation have been taken care of in advance, material data, boundary conditions, friction, FLC and others where determined for the two materials in investigation — a mild steel and a dual phase steel HXT500X. The results of the experiments have been used to design the descriptions of two different benchmark runs for the simulation. The simulations with different programs as well as with different parameters showed on one hand negligible and on the other hand parameters with strong impact on the result — thereby having a different impact on a possible material failure prediction.

  15. Getting shops to voluntarily stop selling cheap, strong beers and ciders: a time-series analysis evaluating impacts on alcohol availability and purchasing.

    Science.gov (United States)

    Pliakas, T; Lock, K; Jones, A; Aalders, S; Egan, M

    2018-02-13

    'Reducing the Strength' (RtS) is a public health initiative encouraging retailers to voluntarily stop selling cheap, strong beers/ciders (≥6.5% alcohol by volume). This study evaluates the impact of RtS initiatives on alcohol availability and purchasing in three English counties with a combined population of 3.62 million people. We used a multiple baseline time-series design to examine retail data over 29 months from a supermarket chain that experienced a two-wave, area-based role out of RtS: initially 54 stores (W1), then another 77 stores (W2). We measured impacts on units of alcohol sold (primary outcome: beers/ciders; secondary outcome: all alcoholic products), economic impacts on alcohol sales and substitution effects. We observed a non-significant W1 increase (+3.7%, 95% CI: -11.2, 21.0) and W2 decrease (-6.8%, 95% CI: -20.5, 9.4) in the primary outcome. We observed a significant W2 decrease in units sold across all alcohol products (-10.5%, 95% CI: -19.2, -0.9). The direction of effect between waves was inconsistent for all outcomes, including alcohol sales, with no evidence of substitution effects. In the UK, voluntary RtS initiatives appear to have little or no impact on reducing alcohol availability and purchase from the broader population of supermarket customers. © The Author(s) 2018. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  16. Variable anelastic attenuation and site effect in estimating source parameters of various major earthquakes including M w 7.8 Nepal and M w 7.5 Hindu kush earthquake by using far-field strong-motion data

    Science.gov (United States)

    Kumar, Naresh; Kumar, Parveen; Chauhan, Vishal; Hazarika, Devajit

    2017-10-01

    Strong-motion records of recent Gorkha Nepal earthquake ( M w 7.8), its strong aftershocks and seismic events of Hindu kush region have been analysed for estimation of source parameters. The M w 7.8 Gorkha Nepal earthquake of 25 April 2015 and its six aftershocks of magnitude range 5.3-7.3 are recorded at Multi-Parametric Geophysical Observatory, Ghuttu, Garhwal Himalaya (India) >600 km west from the epicentre of main shock of Gorkha earthquake. The acceleration data of eight earthquakes occurred in the Hindu kush region also recorded at this observatory which is located >1000 km east from the epicentre of M w 7.5 Hindu kush earthquake on 26 October 2015. The shear wave spectra of acceleration record are corrected for the possible effects of anelastic attenuation at both source and recording site as well as for site amplification. The strong-motion data of six local earthquakes are used to estimate the site amplification and the shear wave quality factor ( Q β) at recording site. The frequency-dependent Q β( f) = 124 f 0.98 is computed at Ghuttu station by using inversion technique. The corrected spectrum is compared with theoretical spectrum obtained from Brune's circular model for the horizontal components using grid search algorithm. Computed seismic moment, stress drop and source radius of the earthquakes used in this work range 8.20 × 1016-5.72 × 1020 Nm, 7.1-50.6 bars and 3.55-36.70 km, respectively. The results match with the available values obtained by other agencies.

  17. Competitiveness of hydrogen production by High Temperature Electrolysis: Impact of the heat source and identification of key parameters to achieve low production costs

    Energy Technology Data Exchange (ETDEWEB)

    Rivera-Tinoco, R. [MINES ParisTech, Centre Energetique et Procedes, 60 bd. Saint Michel, 75006 Paris (France); Commissariat a l' Energie Atomique et aux Energies Alternatives, CEA, DEN, I-tese, F-91191 Gif-sur-Yvette (France); Mansilla, C. [Commissariat a l' Energie Atomique et aux Energies Alternatives, CEA, DEN, I-tese, F-91191 Gif-sur-Yvette (France); Bouallou, C. [MINES ParisTech, Centre Energetique et Procedes, 60 bd. Saint Michel, 75006 Paris (France)

    2010-12-15

    Among the more efficient and sustainable processes that are studied for massive hydrogen production, High Temperature steam Electrolysis seems a promising process. When operating in the autothermal mode, this process does not require a high temperature source for the electrolysis reaction but only a thermal energy source able to supply enough heat to vaporize water. Using a simplified economic model, we assess the impact of the temperature, pressure and thermal energy cost of the heat source on the process competitiveness. Results show that medium temperature thermal energy sources could be coupled to the High Temperature Electrolysis process without resulting in strong overcosts. Besides, key parameters are also identified among the electrolyzer characteristics. Relevant results indicate that R and D on electrolysis cells must continue focusing on the lifespan of these equipments, for which a target lifespan of 3 years could be established. (author)

  18. Impact of prior assumptions on Bayesian estimates of inflation parameters and the expected gravitational waves signal from inflation

    International Nuclear Information System (INIS)

    Valkenburg, Wessel; Hamann, Jan; Krauss, Lawrence M.

    2008-01-01

    There has been much recent discussion, and some confusion, regarding the use of existing observational data to estimate the likelihood that next-generation cosmic microwave background (CMB) polarization experiments might detect a nonzero tensor signal, possibly associated with inflation. We examine this issue in detail here in two different ways: (1) first we explore the effect of choice of different parameter priors on the estimation of the tensor-to-scalar ratio r and other parameters describing inflation, and (2) we examine the Bayesian complexity in order to determine how effectively existing data can constrain inflationary parameters. We demonstrate that existing data are not strong enough to render full inflationary parameter estimates in a parametrization- and prior-independent way and that the predicted tensor signal is particularly sensitive to different priors. For parametrizations where the Bayesian complexity is comparable to the number of free parameters we find that a flat prior on the scale of inflation (which is to be distinguished from a flat prior on the tensor-to-scalar ratio) leads us to infer a larger, and in fact slightly nonzero tensor contribution at 68% confidence level. However, no detection is claimed. Our results demonstrate that all that is statistically relevant at the current time is the (slightly enhanced) upper bound on r, and we stress that the data remain consistent with r=0.

  19. Influence of the Tabor parameter on the adhesive normal impact of spheres in Maugis-Dugdale approximation

    Science.gov (United States)

    Willert, E.; Lyashenko, I. A.; Popov, V. L.

    2017-10-01

    We study the influence of the adhesive interaction range on the coefficient of restitution in the normal impact of spheres by analytical and semi-analytical means based on a Maugis-Dugdale model for the adhesive stress. It is found, that—depending on the value of the Tabor parameter—the impact may start and end with and without direct contact between the surfaces. The hysteretic loss of energy takes its maximum value in the JKR-limit, which for even quite large values of the Tabor parameter noticeably overestimates this loss. Our findings can be applied for the rigorous study of adhesive collisions of elastic particles with and without friction.

  20. The location of the tibial accelerometer does influence impact acceleration parameters during running.

    Science.gov (United States)

    Lucas-Cuevas, Angel Gabriel; Encarnación-Martínez, Alberto; Camacho-García, Andrés; Llana-Belloch, Salvador; Pérez-Soriano, Pedro

    2017-09-01

    Tibial accelerations have been associated with a number of running injuries. However, studies attaching the tibial accelerometer on the proximal section are as numerous as those attaching the accelerometer on the distal section. This study aimed to investigate whether accelerometer location influences acceleration parameters commonly reported in running literature. To fulfil this purpose, 30 athletes ran at 2.22, 2.78 and 3.33 m · s -1 with three accelerometers attached with double-sided tape and tightened to the participants' tolerance on the forehead, the proximal section of the tibia and the distal section of the tibia. Time-domain (peak acceleration, shock attenuation) and frequency-domain parameters (peak frequency, peak power, signal magnitude and shock attenuation in both the low and high frequency ranges) were calculated for each of the tibial locations. The distal accelerometer registered greater tibial acceleration peak and shock attenuation compared to the proximal accelerometer. With respect to the frequency-domain analysis, the distal accelerometer provided greater values of all the low-frequency parameters, whereas no difference was observed for the high-frequency parameters. These findings suggest that the location of the tibial accelerometer does influence the acceleration signal parameters, and thus, researchers should carefully consider the location they choose to place the accelerometer so that equivalent comparisons across studies can be made.

  1. The Impact of Gate-Driver Parameters Variation and Device Degradation in the PV-Inverter Lifetime

    DEFF Research Database (Denmark)

    Sintamarean, Nicolae Cristian; Wang, Huai; Blaabjerg, Frede

    2014-01-01

    -Thermal model and the lifetime model of the power semiconductor devices. A simulation model able to consider a one year real field operation conditions (solar irradiance and ambient temperature) is developed. Thus, one year estimation of the converter devices thermal loading distribution is achieved...... and is further used as an input to a lifetime model. The proposed reliability oriented design tool is used to study the impact of MP-variation, Gate-Driver (GD) parameters variation and device degradation in the PVinverter lifetime. The obtained results indicate that in order to improve the accuracy...... of the lifetime estimation it is crucial to consider also the device degradation feedback. Moreover the MP of the field where the PV-inverter is operating and the GD parameters selection has an important impact in the converter reliability and it should be considered from the design stage to better optimize...

  2. Onium-onium scattering at fixed impact parameter: exact equivalence between the color dipole model and the BFKL pomeron

    International Nuclear Information System (INIS)

    Navelet, H.

    1998-01-01

    We compute the onium-onium scattering amplitude at fixed impact parameter in the framework of the perturbative QCD dipole model. Relying on the conformal properties of the dipole cascade and of the elementary dipole-dipole scattering amplitude, we obtain an exact result for this onium-onium scattering amplitude, which is proved to be identical to the BFKL result, and which exhibits the frame invariance of the calculation. The asymptotic expression for this amplitude and for the dipole distribution in an onium at fixed impact parameter agree with previous numerical simulations. We show how it is possible to describe onium-e ± deep inelastic scattering in the dipole model, relying on k T -factorization properties. The elementary scattering amplitudes involved in the various processes are computed using eikonal techniques. (orig.)

  3. Dynamic impact characteristics of KN-18 SNF transport cask - Part 2: Sensitivity analysis of modeling and design parameters

    International Nuclear Information System (INIS)

    Kim, Kap-Sun; Kim, Jong-Soo; Choi, Kyu-Sup; Shin, Tae-Myung; Yun, Hyun-Do

    2010-01-01

    In Part 1 of this study, an advanced numerical simulation method was proposed to investigate the impact characteristics of the KN-18 spent nuclear fuel (SNF) transport cask recently developed in Korea and verified against the experimental results. In this study, sensitivity analyses are carried out using the proposed numerical simulation method to investigate the effects of the various modeling and design parameters, such as material model assumption, modeling methodology, analytical assumptions, and design variables that can affect the impact characteristics of a cask and the accuracy of the numerical results. These parametric analyses were also performed to provide a basis for correlations with test results that is closer to reality than merely conservative as a means of benchmarking the numerical models. In addition, the parametric analysis results are compared against the experimental results, and the sensitivities of each parameter are summarized to provide references for the future design and analysis of SNF transport casks.

  4. Reliability analysis of different structure parameters of PCBA under drop impact

    Science.gov (United States)

    Liu, P. S.; Fan, G. M.; Liu, Y. H.

    2018-03-01

    The establishing process of PCBA is modelled by finite element analysis software ABAQUS. Firstly, introduce the Input-G method and the fatigue life under drop impact are introduced and the mechanism of the solder joint failure in the process of drop is analysed. The main reason of solder joint failure is that the PCB component is suffering repeated tension and compression stress during the drop impact. Finally, the equivalent stress and peel stress of different solder joint and plate-level components under different impact acceleration are also analysed. The results show that the reliability of tin-silver copper joint is better than that of tin- lead solder joint, and the fatigue life of solder joint expectancy decrease as the impact pulse amplitude increases.

  5. Parameters affecting the environmental impact of a range of dairy farming systems in Denmark, Germany and Italy

    DEFF Research Database (Denmark)

    Guerci, Matteo; Knudsen, Marie Trydeman; Bava, L.

    2013-01-01

    in the farms with the highest stocking rate. The organic Danish farms had the lowest impact on biodiversity loss, which in general was positively influenced by the share of grassland in the system. A high proportion of grassland also had a significant positive effect on GWP, acidification and energy use...... systems (confinement vs. pasture) and annual production levels (6275–10,964 kg ECM cow−1). There was large variability in stocking rates (1.1–11.0 LU ha−1) among farms, which has a major impact on the production per unit area of farmland, on feed self-sufficiency and on farm surplus of nitrogen...... of conventional soymeal in the feed concentrate. There were strong and positive correlations between the four impact categories, and overall the results indicate that improving greenhouse gas emissions would improve the general environmental sustainability of the dairy farm. The land occupation was lowest...

  6. The impact of parameter estimation on computerized adaptive testing with item cloning

    NARCIS (Netherlands)

    Glas, Cornelis A.W.

    2005-01-01

    Item cloning techniques can greatly reduce the cost of item writing and enhance the flexibility of item presentation. An important consequence of cloning is that it may cause variability in the item parameters. Recently, Glas and van der Linden (in press, 2005) proposed a multilevel item response

  7. The impact of parameter estimation on computerized adaptive testing with item cloning

    NARCIS (Netherlands)

    Glas, Cornelis A.W.

    Item cloning techniques can greatly reduce the cost of item writing and enhance the flexibility of item presentation. An important consequence of cloning is that it may cause variability in the item parameters. Recently, Glas and van der Linden (in press, 2005) proposed a multilevel item response

  8. Impact of physicochemical parameters on phytoplankton compositions and abundances in Selameko Manmade Reservoir, Debre Tabor, South Gondar, Ethiopia

    Science.gov (United States)

    Wassie, Tilahun Adugna; Melese, Ayalew Wondie

    2017-07-01

    Impact of physicochemical parameters on 2 compositions and abundances in Selameko Reservoir, Debre Tabor, South Gondar from August 2009 to May 2010 was assessed. Water quality parameters, such as temperature, water transparency, water depth, dissolved oxygen, pH, total dissolved solids, phosphate, nitrate, and silicate were measured in situ from two sites (littoral and open water zone) of the reservoir. Phytoplankton compositions and abundances were analyzed in Tana fisheries and other aquatic organisms' research center. ANOVA result of the physicochemical parameters included chlorophyll-a showed the presence of significance difference among seasons and between sites ( P Diatom, Blue green algae and Green algae) of phytoplankton were identified during the study period. From all groups, diatoms were the most abundant at both sites and Blue green algae were the least abundant. ANOVA of all phytoplankton showed highly significant difference among seasons and between sites ( P < 0.05). ANOVA of all phytoplankton showed highly significant difference among seasons and between sites ( P < 0.05). Based on the stepwise regression, a total number of phytoplanktons had positive correlation with some of the physicochemical parameters (R2 = 0.99, P < 0.001, N = 16). The study concluded that some of physicochemical parameters (NO3-N and PO4-P) indicated the presence of reservoir water pollution. This is supported by the presence of pollution-resistant phytoplankton species such as Melosira and Microcystis. The reservoir water was eutrophic (productive) throughout the year. To avoid such pollution, basin and reservoir management are recommended.

  9. Conditioning rainfall-runoff model parameters for ungauged catchments and land management impacts analysis

    Directory of Open Access Journals (Sweden)

    N. Bulygina

    2009-06-01

    Full Text Available Data scarcity and model over-parameterisation, leading to model equifinality and large prediction uncertainty, are common barriers to effective hydrological modelling. The problem can be alleviated by constraining the prior parameter space using parameter regionalisation. A common basis for regionalisation in the UK is the HOST database which provides estimates of hydrological indices for different soil classifications. In our study, Base Flow Index is estimated from the HOST database and the power of this index for constraining the parameter space is explored. The method is applied to a highly discretised distributed model of a 12.5 km2 upland catchment in Wales. To assess probabilistic predictions against flow observations, a probabilistic version of the Nash-Sutcliffe efficiency is derived. For six flow gauges with reliable data, this efficiency ranged between 0.70 and 0.81, and inspection of the results shows that the model explains the data well. Knowledge of how Base Flow Index and interception losses may change under future land use management interventions was then used to further condition the model. Two interventions are considered: afforestation of grazed areas, and soil degradation associated with increased grazing intensity. Afforestation leads to median reduction in modelled runoff volume of 24% over the simulated 3 month period; and a median peak flow reduction ranging from 12 to 15% over the six gauges for the largest simulated event. Uncertainty in all results is low compared to prior uncertainty and it is concluded that using Base Flow Index estimated from HOST is a simple and potentially powerful method of conditioning the parameter space under current and future land management.

  10. The impact of a stochastic gravitational-wave background on pulsar timing parameters

    Science.gov (United States)

    Ellis, J. A.; McLaughlin, M. A.; Verbiest, J. P. W.

    2011-11-01

    Gravitational waves are predicted by Einstein's theory of general relativity as well as other theories of gravity. The rotational stability of the fastest pulsars means that timing of an array of these objects can be used to detect and investigate gravitational waves. Simultaneously, however, pulsar timing is used to estimate spin period, period derivative, astrometric and binary parameters. Here we calculate the effects that a stochastic background of gravitational waves has on pulsar timing parameters through the use of simulations and data from the millisecond pulsars PSR J0437-4715 and PSR J1713+0747. We show that the reported timing uncertainties become underestimated with increasing background amplitude by up to a factor of ˜10 for a stochastic gravitational-wave background amplitude of A= 5 × 10-15, where A is the amplitude of the characteristic strain spectrum at one-year gravitational wave periods. We find evidence for prominent low-frequency spectral leakage in simulated data sets including a stochastic gravitational-wave background. We use these simulations along with independent very long baseline interferometry (VLBI) measurements of parallax to set a 2σ upper limit of A≤ 9.1 × 10-14. We find that different supermassive black hole assembly scenarios do not have a significant effect on the calculated upper limits. We also test the effects that ultralow-frequency (10-12 to 10-9 Hz) gravitational waves have on binary pulsar parameter measurements and find that the corruption of these parameters is less than those due to 10-9 to 10-7 Hz gravitational waves.

  11. Impact of asymptomatic urogenital tract infections on ejaculate parameters in infertile men with varicocele

    Directory of Open Access Journals (Sweden)

    L. F. Kurilo

    2016-01-01

    Full Text Available Varicocele, a pathology developing in 15 % males, is associated with 30 % male infertility cases. The role of urogenital infections coinciding with varicocele in infertile men has not been studied in sufficient detail.Objective: to examine the effects of bacterial and viral infections on ejaculate parameters in infertile patients with varicocele. The study included 49 patients with infertility and varicocele and 26 healthy males undergoing prophylactic medical examination. Highlevel infection was recorded after examination of ejaculates and urethral scrapes of 49 patients: bacterial (30.6 % and viral (14.3 % pathogens. Quantitative analysis of viral DNA showed high contamination of ejaculates with herpes viruses (> 3 lg10/ml. Detailed analysis of spermatograms demonstrated a decrease in all basic parameters in patients with varicocele and infertility compared with those in healthy subjects. The presence of infectious agents had a statistically significant negative effect on ejaculate parameters. Spermiological examination revealed high level of sperm abnormalities (astenozoospermia, oligoteratozoospermia, and oligoastenoteratozoospermia in patients with infertility, varicocele and bacterioviral infection of urogenital tract compared with uninfected infertile patients with varicocele. Laboratory tests for bacterial and viral infections should be recommended in infertility associated with varicocele even in the absence of clinical signs of these infections. Quantitative analysis of urogenital pathogens allows one to determine the necessity of etiotherapy of hidden infection and to monitor the effectiveness of treatment.

  12. Male urogenital infections: impact of infection and inflammation on ejaculate parameters.

    Science.gov (United States)

    Weidner, W; Pilatz, A; Diemer, Th; Schuppe, H C; Rusz, A; Wagenlehner, F

    2013-08-01

    Urogenital infections and inflammation may contribute significantly to ejaculate parameters essential for male infertility. For this review, data were acquired by a systematic search of the medical literature of the last 5 years. We address the andrological relevance of male urogenital infections and inflammation on ejaculate parameters. The different classification systems of the WHO and NIH are illustrated. In most cases, a separation of the different areas of the urogenital tract, for example, of the prostate, epididymis and testicles, is not possible. The significance of bacteriospermia with common bacteria is discussed. Furthermore, HIV, ascending chlamydial, mycoplasmal and gonococcal infections are relevant. Especially, the relevance of sexually transmitted microorganisms seems to be underestimated. Leukocytospermia is not well defined in its biological significance. Seminal plasma elastase and the cytokine expression reveal better insights into the inflammatory response of the seminal pathways. Sperm antibodies and reactive oxygen species are not usable as indicators for infection and inflammation. Different aspects for an impairment of ejaculate quality have been demonstrated although a direct ascension of microorganisms to the prostate has not been confirmed. Probably, lesions of the epididymis may sustain an ongoing disturbance of sperm parameters. A potential negative influence of urogenital infections and inflammation on sperm function is under discussion. However, the severity of impairment differs according to the underlying infections and the involved compartments. Signs of infections and inflammation in the ejaculate of infertile men are common, and the relevance is often doubtful in spite of microbiological, spermatological and immunological facilities.

  13. Environmental Impacts on the Strength Parameters of Mineral-Acrylic (PMMA/ATH Facade Panels

    Directory of Open Access Journals (Sweden)

    Aleksander Byrdy

    2015-01-01

    Full Text Available Composite mineral-acrylic panels consist in 80% of natural minerals produced from bauxite (aluminium hydroxides (ATH and in 20% from acrylic resin (polymethyl methacrylate (PMMA. This material due to high usability is widely used in interior finishes. Recently, the mineral-acrylic panels have been used as external claddings of buildings. So far, there are several dozen elevations realized worldwide. Due to the variability of the strength parameters of PMMA acrylic resins depending on the environmental influence, a number of tests on samples of mineral-acrylic panels to verify their suitability for use in climate conditions in Central Europe were performed. The studies determined the change of the material parameters after being subjected to aging process in conditions of high temperature, high relative humidity, freeze-thaw cycles, and UV radiation. In the studies parameters such as flexural strength and modulus of elasticity were measured at a reference temperature of 23°C. In raised and lowered temperatures only the tensile strength tests were conducted. Due to the lack of information in the available literature, the authors carried out tests of the temperature influence on the PMMA/ATH composite modulus of elasticity and flexural strength which is crucial in designing process.

  14. Measurement of nonlinear fracture parameter T integral under impact loading using laser caustic method

    International Nuclear Information System (INIS)

    Nishioka, T.; Sakai, K.; Murakami, T.; Matsuo, S.; Sakakura, K.

    1991-01-01

    In order to establish a sound design methodology assuring the integrity of nuclear structures against nonlinear static and dynamic fractures, a unified crack tip parameter is essential due to the existence of various aspects of material behavior in such structures. However, so-called J integral loses its theoretical validity when a crack grows dynamically or elastoplastically, or when a material is subjected to dynamic loading or elastic-plastic unloading. Dynamic J integral has been derived, which has the same features as those of static J integral. Later, a more general path-independent integral which is valid for any material-constitutive model under quasi-static and dynamic conditions was derived. This integral has the great potential as a unified crack tip parameter. Nonlinear dynamic fracture parameter T integral, the hybrid numerical-experimental method for T measurement, and the measurement of the T integral in dynamic tear test are described. The high speed photographs of the caustic pattern in dynamic tear test specimens were taken by a laser caustic method. (K.I.)

  15. Responses of aquatic communities to physical and chemical parameters in agriculturally impacted coastal river systems

    CSIR Research Space (South Africa)

    Petersen, Chantel

    2017-04-05

    Full Text Available , over a period of two years (wet and dry seasons). At upstream sites low electrolytes (electrical conductivity: 12-30 mS m) and nutrients (total nitrogen: <1 mg L) were recorded. Moving down the longitudinal gradient agricultural influences impacted...

  16. The Impact of Economic Parameter Uncertainty Growth on Regional Energy Demand Assessment

    Directory of Open Access Journals (Sweden)

    Olga Vasilyevna Mazurova

    2017-06-01

    Full Text Available The article deals with the forecasting studies based on the energy demand and prices in the region in terms of the complex interconnections between economy (and energy and the growth of uncertainty of the future development of the country and territories. The authors propose a methodological approach, which combines the assessment of the price elasticity of energy demand with the optimization of energy and fuel regional supply. In this case, the price elasticity of demand is determined taking into account the comparison of cost-effectiveness of using different types of fuel and energy by different consumers. The originality of the proposed approach consists in simulating the behaviour of suppliers’ (energy companies and large customers’ (power plants, boiler rooms, industry, transport, population depending on energy price changes, the existing and new technologies, energy-saving activities and restrictions on fuel supplies. To take into account the uncertainty of future economic and energy conditions, some parameters such as prospective technical and economic parameters, price, technological parameters are set as the intervals of possible values with different probability levels. This approach allows making multivariate studies with different combinations of the expected conditions and receiving as a result the range of the projected values of studied indicators. The multivariate calculations show that the fuel demand has a nonlinear dependence on the consumer characteristics, pricing, projection horizon, and the nature of the future conditions uncertainty. The authors have shown that this effect can be significant and should be considered in the forecasts of the development of fuel and energy sector. The methodological approach and quantitative evaluation can be used to improve the economic and energy development strategies of the country and regions

  17. Impact of water temperature and structural parameters on the hydraulic labyrinth-channel emitter performance

    Directory of Open Access Journals (Sweden)

    Ahmed I. Al-Amoud

    2014-06-01

    Full Text Available The effects of water temperature and structural parameters of a labyrinth emitter on drip irrigation hydraulic performance were investigated. The inside structural parameters of the trapezoidal labyrinth emitter include path width (W and length (L, trapezoidal unit numbers (N, height (H, and spacing (S. Laboratory experiments were conducted using five different types of labyrinth-channel emitters (three non-pressure compensating and two pressure-compensating emitters commonly used for subsurface drip irrigation systems. The water temperature effect on the hydraulic characteristics at various operating pressures was recorded and a comparison was made to identify the most effective structural parameter on emitter performance. The pressure compensating emitter flow exponent (x average was 0.014, while non-pressure compensating emitter’s values average was 0.456, indicating that the sensitivity of non-pressure compensating emitters to pressure variation is an obvious characteristic (p<0.001 of this type of emitters. The effects of water temperature on emitter flow rate were insignificant (p>0.05 at various operating pressures, where the flow rate index values for emitters were around one. The effects of water temperature on manufacturer’s coefficient of variation (CV values for all emitters were insignificant (p>0.05. The CV values of the non-pressure compensating emitters were lower than those of pressure compensating emitters. This is typical for most compensating models because they are manufactured with more elements than non-compensating emitters are. The results of regression analysis indicate that N and H are the essential factors (p<0.001 to affect the hydraulic performance.

  18. Impact of structural parameters on the radon exhalation of building materials: Preliminary study

    International Nuclear Information System (INIS)

    Roelofs, L.M.M.

    1993-01-01

    Samples of mortar and sand-lime pieces with different percentages of fly ash are hardened at different relative humidities. The porosity distribution, the moisture and the radon exhalation of these samples are determined. Based on the data of the above-mentioned analyses, the thickness of the adsorbed water layer in the water-filled pores is estimated. The correlation between the structural parameters and the radon exhalation is investigated. If the radon exhalation process can be modelled, the radiation risk of applying fly ash in building materials can be controlled or reduced. The results do not yet show a clear indication. The applied methods have to be considered in more detail

  19. Impact of synthesis parameters on structural and magnetic characteristics of Co-based nanoparticles

    International Nuclear Information System (INIS)

    Mourdikoudis, S.; Simeonidis, K.; Tsiaoussis, I.; Dendrinou-Samara, C.; Angelakeris, M.; Kalogirou, O.

    2009-01-01

    Two different Co-based nanostructures were produced via thermolytic decomposition or reduction of proper cobalt precursors in organic solvents under vigorous stirring. The effect of synthesis parameters on the shape, size, and composition of the particles was examined. We present the differences in the structural and magnetic properties among the as-prepared sub-micron Co 'polypod-like' particles, which display a remarkable value for saturation magnetization (182 emu/g), and the hollow CoO nanoparticles, which exhibit weak ferromagnetic features.

  20. Impact of Seminal Plasma Trace Elements on Human Sperm Motility Parameters

    Directory of Open Access Journals (Sweden)

    Hashemi Mohammad Mostakhdem

    2018-03-01

    Full Text Available Introduction. Human seminal plasma contains a variety of macro and trace elements including magnesium (Mg, copper (Cu, zinc (Zn, and iron (Fe that have essential roles in normal functioning of semen and its quality. The imbalance of these elements has been reported in several pathologic and male infertility disorders. Therefore, this study aimed to determine the levels of these elements in seminal plasma samples, their relationships with each other and their impact on sperm motility.

  1. Impact of Seminal Plasma Trace Elements on Human Sperm Motility Parameters

    OpenAIRE

    Hashemi Mohammad Mostakhdem; Behnampour Nasser; Nejabat Mojgan; Tabandeh Afsaneh; Ghazi-Moghaddam Behrouz; Joshaghani Hamid Reza

    2018-01-01

    Introduction. Human seminal plasma contains a variety of macro and trace elements including magnesium (Mg), copper (Cu), zinc (Zn), and iron (Fe) that have essential roles in normal functioning of semen and its quality. The imbalance of these elements has been reported in several pathologic and male infertility disorders. Therefore, this study aimed to determine the levels of these elements in seminal plasma samples, their relationships with each other and their impact on sperm motility.

  2. Analysis of Impact of Chosen Parameters on the Wear of Camshft

    Directory of Open Access Journals (Sweden)

    Burdzik R.

    2014-10-01

    Full Text Available The paper provides an analysis of the reasons for excessive wear of the camshafts system components based on models developed to describe the impact of selected material, technological and operational factors. The subject of the research was wear of camshaft cams studied in accordance with results of operation tests. Based on the said tests, the dependence of wear intensity of cams from their angular position was established. The respective calculation results enabled the function of cam fallibility to be determined.

  3. Impact of ambiguity resolution and application of transformation parameters obtained by regional GNSS network in Precise Point Positioning

    Science.gov (United States)

    Gandolfi, S.; Poluzzi, L.; Tavasci, L.

    2012-12-01

    Precise Point Positioning (PPP) is one of the possible approaches for GNSS data processing. As known this technique is faster and more flexible compared to the others which are based on a differenced approach and constitute a reliable methods for accurate positioning of remote GNSS stations, even in some remote area such as Antarctica. Until few years ago one of the major limits of the method was the impossibility to resolve the ambiguity as integer but nowadays many methods are available to resolve this aspect. The first software package permitting a PPP solution was the GIPSY OASIS realized, developed and maintained by JPL (NASA). JPL produce also orbits and files ready to be used with GIPSY. Recently, using these products came possible to resolve ambiguities improving the stability of solutions. PPP permit to estimate position into the reference frame of the orbits (IGS) and when coordinate in others reference frames, such al ITRF, are needed is necessary to apply a transformation. Within his products JPL offer, for each day, a global 7 parameter transformation that permit to locate the survey into the ITRF RF. In some cases it's also possible to create a costumed process and obtain analogous parameters using local/regional reference network of stations which coordinates are available also in the desired reference frame. In this work some tests on accuracy has been carried out comparing different PPP solutions obtained using the same software packages (GIPSY) but considering the ambiguity resolution, the global and regional transformation parameters. In particular two test area have been considered, first one located in Antarctica and the second one in Italy. Aim of the work is the evaluation of the impact of ambiguity resolution and the use of local/regional transformation parameter in the final solutions. Tests shown how the ambiguity resolution improve the precision, especially in the EAST component with a scattering reduction about 8%. And the use of global

  4. Impact of spectral nudging and domain size in studies of RCM response to parameter modification

    Energy Technology Data Exchange (ETDEWEB)

    Separovic, Leo; Laprise, Rene [Universite du Quebec a Montreal, Centre pour l' Etude et la Simulation du Climat a l' Echelle Regionale (ESCER), Montreal, QC (Canada); Universite du Quebec a Montreal (UQAM), Montreal, QC (Canada); Elia, Ramon de [Universite du Quebec a Montreal, Centre pour l' Etude et la Simulation du Climat a l' Echelle Regionale (ESCER), Montreal, QC (Canada); Consortium Ouranos, Montreal, QC (Canada)

    2012-04-15

    The paper aims at finding an RCM configuration that facilitates studies devoted to quantifying RCM response to parameter modification. When using short integration times, the response of the time-averaged variables to RCM modification tend to be blurred by the noise originating in the lack of predictability of the instantaneous atmospheric states. Two ways of enhancing the signal-to-noise ratio are studied in this work: spectral nudging and reduction of the computational domain size. The approach followed consists in the analysis of the sensitivity of RCM-simulated seasonal averages to perturbations of two parameters controlling deep convection and stratiform condensation, perturbed one at a time. Sensitivity is analyzed within different simulation configurations obtained by varying domain size and using the spectral nudging option. For each combination of these factors multiple members of identical simulations that differ exclusively in initial conditions are also generated to provide robust estimates of the sensitivities (the signal) and sample the noise. Results show that the noise magnitude is decreased both by reduction of domain size and the spectral nudging. However, the reduction of domain size alters some sensitivity signals. When spectral nudging is used significant alterations of the signal are not found. (orig.)

  5. Impact of the α parameter on the microstability of internal transport barriers

    Science.gov (United States)

    Bourdelle, C.; Hoang, G. T.; Litaudon, X.; Roach, C. M.; Tala, T.; ITPA Topical Group on Transport; Physics, ITB; International ITB Database Working Group

    2005-02-01

    In plasmas exhibiting an internal transport barrier (ITB), locally very high pressure gradient (∇P) is obtained. It induces high values of the magnetohydrodynamic α parameter (α = -q 2 βR∇P/P, with R the major radius, q the safety factor, P the pressure, ∇ the radial gradient and β the ratio between kinetic and magnetic pressure). Similarly to low or negative magnetic shear (s), high α reduces the curvature and ∇ B drifts driving curvature-type microinstabilities. Therefore, high values of α can stabilize part of the microturbulence, which leads to higher pressure gradient and to even higher α. This possibility for entering a positive feedback loop is very attractive to sustain ITBs in high performance plasmas. Indeed, α scales favourably with higher pressure and does not require any external momentum input. In this paper, after having discussed the α stabilization mechanism in detail, we report the experimental microstability analyses of ITBs from an international multi-machine database—the International Tokamak Physics Activity database, accessible on the webhttp://tokamak-profiledb.ukaea.org.uk/ . We show that α is indeed a relevant parameter of ITB physics that should be taken into account in interpretative and predictive one-dimensional transport codes.

  6. Impact of strong selection for the PrP major gene on genetic variability of four French sheep breeds (Open Access publication

    Directory of Open Access Journals (Sweden)

    Pantano Thais

    2008-11-01

    Full Text Available Abstract Effective selection on the PrP gene has been implemented since October 2001 in all French sheep breeds. After four years, the ARR "resistant" allele frequency increased by about 35% in young males. The aim of this study was to evaluate the impact of this strong selection on genetic variability. It is focussed on four French sheep breeds and based on the comparison of two groups of 94 animals within each breed: the first group of animals was born before the selection began, and the second, 3–4 years later. Genetic variability was assessed using genealogical and molecular data (29 microsatellite markers. The expected loss of genetic variability on the PrP gene was confirmed. Moreover, among the five markers located in the PrP region, only the three closest ones were affected. The evolution of the number of alleles, heterozygote deficiency within population, expected heterozygosity and the Reynolds distances agreed with the criteria from pedigree and pointed out that neutral genetic variability was not much affected. This trend depended on breed, i.e. on their initial states (population size, PrP frequencies and on the selection strategies for improving scrapie resistance while carrying out selection for production traits.

  7. Thermodynamic evaluation of the impact of strongly swelling polymer hydrogels with ionic silver on the water retention capacity of sandy substrate

    Science.gov (United States)

    Smagin, A. V.

    2017-01-01

    The impact of two types of strongly swelling polymer hydrogel (SSPH) on the water retention capacity of quartz sand in pure water and Ag+ solutions (10-100 mg/l) has been studied by using a centrifugation method in a wide range of thermodynamic water potential (Gibbs energy) from 0 to 3030 J/kg. The experimental data for the water retention curves (WRC) were estimated by the van Genuchten model. Both hydrogels - the Aquasorb preparation (Germany) with hydrophilic properties and high degree of swelling in pure water (700-1000 g H2O/g) and the new Russian amphiphilic SSPH with a peat filler (degree of swelling 500-700 g H2O/g) were very effective as water adsorbing soil conditioners in relatively small doses from 0.05 to 0.3% per mass of dry (105°C) soil substrate. The water retention capacity of sandy substrate increases under the influence of SSPH with 2-3 times up to the level of native loamy sands and loams. Adding Ag+ to the water solution results just for the highest concentration of SSPH (0.3%) and iconic silver (100 mg/l) in a significant decrease of the water retention in the soil-gel compositions.

  8. Impact of anthropometrical parameters on portal vein diameter and liver size in a subset of Karachi based population.

    Science.gov (United States)

    Raza Siddiqui, Tanya; Hassan, Nuzhat; Gul, Pashmina

    2014-03-01

    The purpose was to study the impact of anthropometrical parameters on portal vein diameter and liver size by ultrasound in a subset of Karachi population. Four hundred and fifty nine apparently healthy subjects were included in this cross sectional study. After recording weight and height of each subject, Portal vein diameter and both liver lobes were measured by gray scale ultrasonography. Students T test and ANOVA were applied for statistical analyses. With increasing age, portal vein diameter and right lobe of liver increased significantly (p value Sizes of right and left liver lobes also increased with a rise in body mass index (p value size. Age and body mass index are reliable parameters to consider for avoiding false positive diagnosis of hepatomegaly and portal hypertension. Knowing the right and left liver size with respect to anthropometrical measurements also assist a clinician in selecting a subject for liver transplantation.

  9. Impact of Coulomb potential on peak structures arising in momentum and low-energy photoelectron spectra produced in strong-field ionization of laser-irradiated atoms

    Science.gov (United States)

    Pyak, P. E.; Usachenko, V. I.

    2018-03-01

    The phenomenon of pronounced peak structure(s) of longitudinal momentum distributions as well as a spike-like structure of low-energy spectra of photoelectrons emitted from laser-irradiated Ar and Ne atoms in a single ionization process is theoretically studied in the tunneling and multiphoton regimes of ionization. The problem is addressed assuming only the direct above-threshold ionization (ATI) as a physical mechanism underlying the phenomenon under consideration (viz. solely contributing to observed photoelectron momentum distributions (PMD)) and using the Coulomb-Volkov (CV) ansatz within the frame of conventional strong-field approximation (SFA) applied in the length-gauge formulation. The developed CV-SFA approach also incorporates the density functional theory essentially exploited for numerical composition of initial (laser-free) atomic state(s) constructed from atomic orbitals of Gaussian type. Our presented CV-SFA based (and laser focal-volume averaged) calculation results proved to be well reproducing both the pronounced double-peak and/or ATI-like multi-peak structure(s) experimentally observed in longitudinal PMD under conditions of tunneling and/or multiphoton regime, respectively. In addition, our CV-SFA results presented for tunneling regime also suggest and remarkably reproduce a pronounced structure observed in relevant experiments as a ‘spike-like’ enhanced maximum arising in low-energy region (around the value of about 1 eV) of photoelectron spectra. The latter consistency allows to identify and interpret these results as the so-called low-energy structure (LES) since the phenomenon proved to appear as the most prominent if the influence of Coulomb potential on photoelectron continuum states is maximally taken into account under calculations (viz. if the parameter Z in CV’s functions is put equal to 1). Moreover, the calculated LES proved to correspond (viz., established as closely related) to the mentioned double-peak structure arising

  10. Impact of parameter representation in gas-particle partitioning on aerosol yield model prediction

    Science.gov (United States)

    Kelly, Janya L.

    A kinetic box model is used to highlight the importance of parameter representation in predicting the formation of secondary organic aerosol (SOA) from the photo-oxidation of toluene through a subset of the University of Leeds Master Chemical Mechanism (MCM) version 3.1, and a kinetically based gas-particle partitioning approach. The model provides a prediction of the total aerosol yield and a tentative speciation of aerosols initialized from experimental data from York University's indoor smog chamber. A series of model sensitivity experiments were performed to study the relative importance of different parameters in SOA formation, with emphasis on vapour pressure, accommodation coefficient and NOx conditions. Early sensitivity experiments indicate vapour pressure to be a critical parameter in the partitioning and final aerosol yield. Current estimation methods are highly sensitive to boiling point temperature and can lead to the propagation of errors in the model. Of concern is the estimation of vapour pressure for compounds containing organic nitrates (major contributors to the aerosol speciation in this study). Results indicate that approximately +/- 80% error can be expected in the final aerosol mass from errors in the boiling point temperature and vapour pressure estimation methods, and, that for most experiments, this error alone cannot account for a general under prediction in the aerosol mass. Current experimental conditions dictate a very high initial NOx environment and a much higher final aerosol yield compared to other smog chamber studies, leading to the question of whether the model results arise from unique experimental conditions (relative to other chambers), from using different pathways in MCMv3.1 leading to different aerosol speciation (from the high NOx conditions), or from the physical representation of partitioning in the model. Results show that the choice of isopropyl nitrite as the hydroxyl radical oxidation source may be contributing to

  11. Study of the impact of environmental parameters on the operation of CMS RPCs

    CERN Document Server

    Assran, Yasser

    2011-01-01

    CMS (Compact Muon Solenoid) is a general purpose detector designed to run at the highest luminosity at Large Hadron Collider (LHC), CERN, Geneva, Switzerland. The muon system of the CMS experiment relies on Drift Tubes (DT), Cathode Strip Chambers (CSC) and Resistive Plate Chambers (RPC). RPCs are dedicated for the first level muon trigger and they are characterized by bakelite electrodes delimited in a specialized gas volume filled with operational gas mixture. This analysis has been done for the RPC chambers installed in CMS experiment at CERN. The Currents of CMS RPCs chambers are analyzed as a function of environmental parameters such as Temperature, Humidity and pressure, which are important for the operation of the muon detector system. A novel Neural Network approach has been used to analyze the data and to build a model using experimental measurements and combining the results of the simulations. Data from RPC Chambers in CMS experiment are taken and compared to the results from neural Network.

  12. IMPACT OF ZOOTECHNICAL PARAMETERS ON CELL QUALITY OF CATTLE MILK (SEMI-ARID COSTAL TUNISIA

    Directory of Open Access Journals (Sweden)

    R. HAJ MBAREK

    2015-09-01

    Full Text Available The work was realized on a sample of 50 cattle herds, conducted in aboveground, in a coastal area of the semi-arid Tunisia, by using investigation related to cows and their breeding and milking conditions as well as despoliation in milk control data. Analysis of the data relating to the parameters of udder conformation and cow cleanliness revealed that “Udder depth” settings “Udder cleanliness” have been shown to affect the ICC and are considered factors risk of bovine mastitis. The study of breeding and milking conditions highlight some significant factors on changes on the variation of cell counts and the probability of the spread of mastitis, especially the "No disinfection of teat." The level of housing, the analysis revealed that the use of a litter reduced to half the average of ICC which proved highly related to the cleanliness of both the sleeping area as the udder.

  13. The impact of confinement scaling on ITER [International Thermonuclear Experimental Reactor] parameters

    International Nuclear Information System (INIS)

    Reid, R.L.; Galambos, J.D.; Peng, Y.K.M.

    1988-09-01

    Energy confinement scaling is a major concern in the design of the International Thermonuclear Experimental Reactor (ITER). The existing database for tokamaks can be fitted with a number of different confinement scaling expressions that have similar degrees of approximation. These scaling laws predict confinement times for ITER that vary by over an order of magnitude. The uncertainties in the form and magnitude of these scaling laws must be substantially reduced before the plasma performance of ITER can be predicted with adequate reliability. The TETRA systems code is used to calculate the dependence of major ITER parameters on the scaling laws currently in use. Design constraints of interest in the present phase of ITER consideration are used, and the minimum-cost devices arising from these constraints are reviewed. 9 refs., 13 figs., 4 tabs

  14. Impact of Senior Dance on emotional and motor parameters and quality of life of the elderly

    Directory of Open Access Journals (Sweden)

    José Alípio Garcia Gouvêa

    2017-01-01

    Full Text Available To verify the effects of Senior Dance on cognitive and motor parameters and quality of life of elderly people. Methods: pre-experimental study with pre and post-test for a group with a convenience sample composed of 20 elderly of both genders. Participants were evaluated through the agility test, the balance scale and inventories of depression and anxiety, and a questionnaire on quality of life. Elderly people participated in a physical activity program featured as Senior Dance for a period of three months. Results: the intervention resulted in improved scores in most of the variables, with significant results only for anxiety classified as temporary emotional state. Conclusion: Senior Dance was effective as physical exercise to improve the quality of life, as well as the physical and mental health of the elderly.

  15. Theoretical study to investigate the impact of plasma parameters on the catalyst nanoparticle growth

    International Nuclear Information System (INIS)

    Gupta, R; Sharma, S C; Gupta, N

    2017-01-01

    The plasma kinetics based model is adopted to elucidate the effect of plasma parameters on the nucleation and growth mechanism of catalyst nanoparticle. The present model considers the plasma processing of thin catalyst film, power equalization at the film surface, flux and kinetics of plasma species (electrons, ions, and neutrals). In our investigation, it is found that catalyst nanoparticle diameter decreases with increase in ion number density in plasma. Moreover, it is also found that catalyst film thickness significantly affect the catalyst nanoparticle size i.e., catalyst nanoparticle diameter increases with catalyst film thickness. In addition, it is observed that the substrate temperature increases during the plasma processing and finally achieve saturation. Our theoretical results are in good agreement with the experimental results. (paper)

  16. Impact of Reduction Parameters on the Initial Performance and Stability of Ni/(Sc)YSZ Cermet Anodes for SOFCs

    DEFF Research Database (Denmark)

    Ebbehøj, Søren Lyng; Ramos, Tania; Mogensen, Mogens Bjerg

    2012-01-01

    processes for Ni/10Sc1YSZ cells. The Ni/8YSZ cells behaved oppositely with respect to reduction temperature. A hypothesis is proposed relating performance to variations in Ni microstructure, Ni/ceramic contacting and extent of TPB resulting from differences in reduction parameters. Further, the performance......In-situ reduction of Ni cermet anodes produces the porosity and influences the microstructure, performance and stability of the anodes. The impact on initial performance, stability and microstructure of two different reduction procedures currently in use at DTU Energy Conversion with reduction...... stability under high steam conditions was evaluated, and very stable performances and microstructures of the anode layers were observed....

  17. The impact of various parameters on the carbon footprint of milk production in New Zealand and Sweden

    DEFF Research Database (Denmark)

    Flysjö, Anna Maria; Henriksson, Maria; Cederberg, Christel

    2011-01-01

    nitrous oxide emissions from soils. By changing one parameter at a time within ‘reasonable’ limits (i.e. no extreme values assumed), the impact on the total CF was assessed and showed changes of up to 15%. In addition, the uncertainty in CF estimates due to uncertainty in EF for methane from enteric...... on the conceptual framework of lifecycle assessment (LCA), but only for greenhouse gas (GHG) emissions. National average data were used to model the dairy system in each country. Collection of inventory data and calculations of emissions were harmonised to the greatest extent possible for the two systems...

  18. On the SCA-description of the energy- and impact parameter dependence of K-shell ionization cross sections

    International Nuclear Information System (INIS)

    Trautmann, D.; Kauer, T.

    1989-01-01

    We present the application of the SCA-model to impact-parameter and energy-dependent K-shell ionization cross sections for several projectile-target combinations. Then we discuss the successes and failures of the SCA-description and investigate the additional approximations still existing in this approach. It is shown that after the introduction of a fully time-dependent perturbed electronic boundstate wave function many of the former discrepancies between experiment and theory can be resolved and in general very good agreement is obtained. (orig.)

  19. Impact parameter dependence of pion ratio in probing the nuclear symmetry energy using heavy-ion collisions

    OpenAIRE

    Wei, Gao-Feng; He, Guo-Qiang; Cao, Xin-Wei; Lu, Yi-Xin

    2016-01-01

    The impact parameter dependence of \\rpi ratio is examined in heavy-ion collisions at 400MeV/nucleon within a transport model. It is shown that the sensitivity of \\rpi ratio on symmetry energy shows a transition from central to peripheral collisions, i.e., the stiffer symmetry energy leads to a larger \\rpi ratio in peripheral collisions while the softer symmetry energy always leads this ratio to be larger in central collisions. After checking the kinematic energy distribution of \\rpi ratio, we...

  20. The impact of adjuvant chemotherapy in older breast cancer patients on clinical and biological aging parameters

    Science.gov (United States)

    Brouwers, Barbara; Hatse, Sigrid; Lago, Lissandra Dal; Neven, Patrick; Vuylsteke, Peter; Dalmasso, Bruna; Debrock, Guy; Van Den Bulck, Heidi; Smeets, Ann; Bechter, Oliver; Bailur, Jithendra Kini; Kenis, Cindy; Laenen, Annouschka; Schöffski, Patrick; Pawelec, Graham; Journe, Fabrice; Ghanem, Ghanem-Elias; Wildiers, Hans

    2016-01-01

    Purpose This prospective observational study aimed to evaluate the impact of adjuvant chemotherapy on biological and clinical markers of aging and frailty. Methods Women ≥ 70 years old with early breast cancer were enrolled after surgery and assigned to a chemotherapy (Docetaxel and Cyclophosphamide) group (CTG, n=57) or control group (CG, n=52) depending on their planned adjuvant treatment. Full geriatric assessment (GA) and Quality of Life (QoL) were evaluated at inclusion (T0), after 3 months (T1) and at 1 year (T2). Blood samples were collected to measure leukocyte telomere length (LTL), levels of interleukin-6 (IL-6) and other circulating markers potentially informative for aging and frailty: Interleukin-10 (IL-10), Tumor Necrosis Factor Alpha (TNF-α), Insulin-like Growth Factor 1 (IGF-1), Monocyte Chemotactic Protein 1 (MCP-1) and Regulated on Activation, Normal T cell Expressed and Secreted (RANTES). Results LTL decreased significantly but comparably in both groups, whereas IL-6 was unchanged at T2. However, IL-10, TNF-α, IGF-1 and MCP-1 suggested a minor biological aging effect of chemotherapy. Clinical frailty and QoL decreased at T1 in the CTG, but recovered at T2, while remaining stable in the CG. Conclusion Chemotherapy (TC) is unlikely to amplify clinical aging or induce frailty at 1 year. Accordingly, there is no impact on the most established aging biomarkers (LTL, IL-6). PMID:27102154

  1. Impact of Intragranular Substructure Parameters on the Forming Limit Diagrams of Single-Phase B.C.C. Steels

    Directory of Open Access Journals (Sweden)

    Gérald Franz

    2013-11-01

    Full Text Available An advanced elastic-plastic self-consistent polycrystalline model, accounting for intragranular microstructure development and evolution, is coupled with a bifurcation-based localization criterion and applied to the numerical investigation of the impact of microstructural patterns on ductility of single-phase steels. The proposed multiscale model, taking into account essential microstructural aspects, such as initial and induced textures, dislocation densities, and softening mechanisms, allows us to emphasize the relationship between intragranular microstructure of B.C.C. steels and their ductility. A qualitative study in terms of forming limit diagrams for various dislocation networks, during monotonic loading tests, is conducted in order to analyze the impact of intragranular substructure parameters on the formability of single-phase B.C.C. steels.

  2. Impact of nuclear data uncertainties on neutronics parameters of MYRRHA/XT-ADS

    International Nuclear Information System (INIS)

    Sugawara, T.; Stankovskiy, A.; Van den Eynde, G.; Sarotto, M.

    2011-01-01

    A flexible fast spectrum research reactor MYRRHA able to operate in subcritical (driven by a proton accelerator) and critical modes is being developed in SCK-CEN. In the framework of IP EUROTRANS programme the XT-ADS model has been investigated for MYRRHA. This paper reports the comparison of the sensitivity coefficients calculated for different calculation models and the uncertainties deduced from various covariance data for the discussion on the reliability of XT-ADS neutronics design. Sensitivity analysis is based on the comparison of three-dimensional heterogeneous and two-dimensional RZ calculation models. Three covariance data sets were employed to perform uncertainty analysis. The obtained sensitivity coefficients differ substantially between the 3D heterogeneous and RZ homogenized calculation models. The uncertainties deduced from the covariance data strongly depend on the covariance data variation. The covariance data of the nuclear data libraries is an open issue to discuss the reliability of the neutronics design. The uncertainties deduced from the covariance data for XT-ADS are 0.94% and 1.9% by the SCALE-6 44-group and TENDL-2009 covariance data, accordingly. The uncertainties exceed the 0.3% Δk (confidence level 1σ) target accuracy level. To achieve this target accuracy, the uncertainties should be improved by experiments under adequate conditions such as LBE or Pb moderated environment with MOX or Uranium fuel

  3. IMPACT OF ALCOHOL ON HUMAN VITAL SEMINAL PARAMETER WHICH INFLUENCE FERTILITY

    Directory of Open Access Journals (Sweden)

    Abhishek

    2015-07-01

    Full Text Available Alcohol has wide impact (affect on male reproductive function like impotence, loss of sexual interest, gynecomastia and on male infertility. Alcohol can adversely affect the leydig cells which secretes the male hormone testosterone, Several studied have been conducted to evaluate the effect of alcohol in men and results shows reduced testosterone levels in the blood. Alcohol has dual effect on the hypothalamic pituitary – gonadal axis and blocking the release of LH - releasing hormone. 110 subjects were inc luded in the present study amongst whom 25 were non - alcoholic, 53 with low alcoholic and 32 with high alcoholic intake. Our study shows that ethanol exhibits alteration in their spermatozoa concentration, abnormal motility and morphology.

  4. The Impact of Ventricular Assist Device Prior to Transplantation on Morphological Parameters in Cardiac Allografts

    DEFF Research Database (Denmark)

    Wassilew, Katharina

    2017-01-01

    Due to the shortage of donor organs, mechanical circulatory support systems (MCS) are now widely used as a treatment option to bridge the failing heart to transplantation. There are limited data, suggesting that prolonged use of ventricular assist device (VAD) therapy may result in cardiac...... of the level of macrophages on the degree of IF in right ventricular endomyocardial biopsies (EMBs) of cardiac allografts. Methods: We evaluated all consecutive EMBs of cardiac allografts from 254 patients taken between 01/2011 and 12/2012.With regard to pre-transplant MCS treatment, patients were divided....... The Cochran-Mantel-Haenzsel test was applied to assess significance of the differences in interactions between groups. To evaluate the impact of bridge- to- transplant mechanical circulatory support on development on transplant vasculopathy in cardiac allografts, the intramyocardial terminal arterial network...

  5. Impact of process parameters and design options on heat leaks of straight cryogenic distribution lines

    CERN Document Server

    Duda, Pawel; Chorowski, Maciej Pawel; Polinski, J

    2017-01-01

    The Future Circular Collider (FCC) accelerator will require a helium distribution system that will exceed the presently exploited transfer lines by almost 1 order of magnitude. The helium transfer line will contain five process pipes protected against heat leaks by a common thermal shield. The design pressure of the FCC process pipe with supercritical helium will be equal to 5.0 MPa, significantly exceeding the 2.0 MPa value in the present, state-of–art transfer lines. The increase of the design pressure requires construction changes to be introduced to the support system, the vacuum barriers and the compensation bellows. This will influence heat flows to the helium. The paper analyses the impact of the increased design pressure on the heat flow. The paper also offers a discussion of the design modifications to the compensation system, including the replacement of stainless steel with Invar—aimed at mitigating the pressure increase.

  6. Impact of process parameters and design options on heat leaks of straight cryogenic distribution lines

    Directory of Open Access Journals (Sweden)

    P. Duda

    2017-03-01

    Full Text Available The Future Circular Collider (FCC accelerator will require a helium distribution system that will exceed the presently exploited transfer lines by almost 1 order of magnitude. The helium transfer line will contain five process pipes protected against heat leaks by a common thermal shield. The design pressure of the FCC process pipe with supercritical helium will be equal to 5.0 MPa, significantly exceeding the 2.0 MPa value in the present, state-of–art transfer lines. The increase of the design pressure requires construction changes to be introduced to the support system, the vacuum barriers and the compensation bellows. This will influence heat flows to the helium. The paper analyses the impact of the increased design pressure on the heat flow. The paper also offers a discussion of the design modifications to the compensation system, including the replacement of stainless steel with Invar®—aimed at mitigating the pressure increase.

  7. Impact of Multileaf Collimator Configuration Parameters on the Dosimetric Accuracy of 6-MV Intensity-Modulated Radiation Therapy Treatment Plans.

    Science.gov (United States)

    Petersen, Nick; Perrin, David; Newhauser, Wayne; Zhang, Rui

    2017-01-01

    The purpose of this study was to evaluate the impact of selected configuration parameters that govern multileaf collimator (MLC) transmission and rounded leaf offset in a commercial treatment planning system (TPS) (Pinnacle 3 , Philips Medical Systems, Andover, MA, USA) on the accuracy of intensity-modulated radiation therapy (IMRT) dose calculation. The MLC leaf transmission factor was modified based on measurements made with ionization chambers. The table of parameters containing rounded-leaf-end offset values was modified by measuring the radiation field edge as a function of leaf bank position with an ionization chamber in a scanning water-tank dosimetry system and comparing the locations to those predicted by the TPS. The modified parameter values were validated by performing IMRT quality assurance (QA) measurements on 19 gantry-static IMRT plans. Planar dose measurements were performed with radiographic film and a diode array (MapCHECK2) and compared to TPS calculated dose distributions using default and modified configuration parameters. Based on measurements, the leaf transmission factor was changed from a default value of 0.001 to 0.005. Surprisingly, this modification resulted in a small but statistically significant worsening of IMRT QA gamma-index passing rate, which revealed that the overall dosimetric accuracy of the TPS depends on multiple configuration parameters in a manner that is coupled and not intuitive because of the commissioning protocol used in our clinic. The rounded leaf offset table had little room for improvement, with the average difference between the default and modified offset values being -0.2 ± 0.7 mm. While our results depend on the current clinical protocols, treatment unit and TPS used, the methodology used in this study is generally applicable. Different clinics could potentially obtain different results and improve their dosimetric accuracy using our approach.

  8. Impact of multileaf collimator configuration parameters on the dosimetric accuracy of 6-MV Intensity-Modulated radiation therapy treatment plans

    Directory of Open Access Journals (Sweden)

    Nick Petersen

    2017-01-01

    Full Text Available The purpose of this study was to evaluate the impact of selected configuration parameters that govern multileaf collimator (MLC transmission and rounded leaf offset in a commercial treatment planning system (TPS (Pinnacle3, Philips Medical Systems, Andover, MA, USA on the accuracy of intensity-modulated radiation therapy (IMRT dose calculation. The MLC leaf transmission factor was modified based on measurements made with ionization chambers. The table of parameters containing rounded-leaf-end offset values was modified by measuring the radiation field edge as a function of leaf bank position with an ionization chamber in a scanning water-tank dosimetry system and comparing the locations to those predicted by the TPS. The modified parameter values were validated by performing IMRT quality assurance (QA measurements on 19 gantry-static IMRT plans. Planar dose measurements were performed with radiographic film and a diode array (MapCHECK2 and compared to TPS calculated dose distributions using default and modified configuration parameters. Based on measurements, the leaf transmission factor was changed from a default value of 0.001 to 0.005. Surprisingly, this modification resulted in a small but statistically significant worsening of IMRT QA gamma-index passing rate, which revealed that the overall dosimetric accuracy of the TPS depends on multiple configuration parameters in a manner that is coupled and not intuitive because of the commissioning protocol used in our clinic. The rounded leaf offset table had little room for improvement, with the average difference between the default and modified offset values being −0.2 ± 0.7 mm. While our results depend on the current clinical protocols, treatment unit and TPS used, the methodology used in this study is generally applicable. Different clinics could potentially obtain different results and improve their dosimetric accuracy using our approach.

  9. Copper nanoparticles/compounds impact agronomic and physiological parameters in cilantro (Coriandrum sativum).

    Science.gov (United States)

    Zuverza-Mena, Nubia; Medina-Velo, Illya A; Barrios, Ana C; Tan, Wenjuan; Peralta-Videa, Jose R; Gardea-Torresdey, Jorge L

    2015-10-01

    The environmental impacts of Cu-based nanoparticles (NPs) are not well understood. In this study, cilantro (Coriandrum sativum) was germinated and grown in commercial potting mix soil amended with Cu(OH)2 (Kocide and CuPRO), nano-copper (nCu), micro-copper (μCu), nano-copper oxide (nCuO), micro-copper oxide (μCuO) and ionic Cu (CuCl2) at either 20 or 80 mg Cu per kg. In addition to seed germination and plant elongation, relative chlorophyll content and micro and macroelement concentrations were determined. At both concentrations, only nCuO, μCuO, and ionic Cu, showed statistically significant reductions in germination. Although compared with control, the relative germination was reduced by ∼50% with nCuO at both concentrations, and by ∼40% with μCuO, also at both concentrations, the difference among compounds was not statistically significant. Exposure to μCuO at both concentrations and nCu at 80 mg kg(-1) significantly reduced (p≤ 0.05) shoot elongation by 11% and 12.4%, respectively, compared with control. Only μCuO at 20 mg kg(-1) significantly reduced (26%) the relative chlorophyll content, compared with control. None of the treatments increased root Cu, but all of them, except μCuO at 20 mg kg(-1), significantly increased shoot Cu (p≤ 0.05). Micro and macro elements B, Zn, Mn, Ca, Mg, P, and S were significantly reduced in shoots (p≤ 0.05). Similar results were observed in roots. These results showed that Cu-based NPs/compounds depress nutrient element accumulation in cilantro, which could impact human nutrition.

  10. Impact of digital prosthodontic planning on dental esthetics: Biometric analysis of esthetic parameters.

    Science.gov (United States)

    Abduo, Jaafar; Bennamoun, Mohammed; Tennant, Marc; McGeachie, John

    2016-01-01

    Improving dental esthetics is a main objective of prosthodontic treatment. Recently, digital diagnostic waxing has been proposed as an alternative to conventional diagnostic waxing; however, the impact on esthetics has not been evaluated. The purpose of this study was to evaluate the impact of diagnostic waxing on biometric esthetic variables and to compare the esthetic outcome achieved by digital waxing with conventional waxing. Three biometric variables were evaluated: perceived frontal proportion (PFP), width/height (W:H) ratio, and symmetry. Maxillary casts of 13 patients were collected. All of them had maxillary anterior teeth that required prosthodontic treatment. Two forms of diagnostic waxing were executed: conventional and digital waxing. Measurements of the esthetic variables were conducted digitally. For the PFP, a frontal image was made and the width of each tooth was measured. Subsequently, the PFP values of the lateral incisor to central incisor and of the canine to central incisor were calculated. In addition, the height and width of each tooth was measured to calculate the W:H ratio. Using the previous measurements, the symmetry between the right and left sides was determined. No consistent or recurrent PFP was detected for any cast. The diagnostic waxing did not alter the PFP of the pretreatment casts. The diagnostic waxing had restored the W:H ratio to what is assumed to be a natural ratio. An improvement in symmetry was detected after the diagnostic waxing and was more prominent after the digital waxing. However, no significant difference was found between the 2 diagnostic waxing methods. The 2 diagnostic waxing methods influenced the esthetic variables of the anterior maxillary teeth and yielded similar outcomes. Digital waxing appears to be a reasonable alternative, but further investigations are needed to ensure its practicality. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights

  11. Ametropia, retinal anatomy, and OCT abnormality patterns in glaucoma. 2. Impacts of optic nerve head parameters

    Science.gov (United States)

    Baniasadi, Neda; Wang, Mengyu; Wang, Hui; Jin, Qingying; Elze, Tobias

    2017-12-01

    Clinicians use retinal nerve fiber layer thickness (RNFLT) measured by optical coherence tomography (OCT) as an adjunct to glaucoma diagnosis. Ametropia is accompanied by changes to the optic nerve head (ONH), which may affect how OCT machines mark RNFLT measurements as abnormal. These changes in abnormality patterns may bias glaucoma diagnosis. Here, we investigate the relationship between OCT abnormality patterns and the following ONH-related and ametropia-associated parameters on 421 eyes of glaucoma patients: optic disc tilt and torsion, central retinal vessel trunk location (CRVTL), and nasal and temporal retinal curvature adjacent to ONH, quantified as nasal/temporal slopes of the inner limiting membrane. We applied multivariate logistic regression with abnormality marks as regressands to 40,401 locations of the peripapillary region and generated spatial maps of locations of false positive/negative abnormality marks independent of glaucoma severity. Effects of torsion and temporal slope were negligible. The effect of tilt could be explained by covariation with ametropia. For CRVTL/nasal slope, abnormality pattern shifts at 7.2%/23.5% of the peripapillary region were detected, respectively, independent of glaucoma severity and ametropia. Therefore, CRVTL and nasal curvature should be included in OCT RNFLT norms. Our spatial location maps may aid clinicians to improve diagnostic accuracy.

  12. Impact of Mergers on USA Parameter Estimation for Nonspinning Black Hole Binaries

    Science.gov (United States)

    McWilliams, Sean T.; Thorpe, James Ira; Baker, John G.; Kelly, Bernard J.

    2011-01-01

    We investigate the precision with which the parameters describing the characteristics and location of nonspinning black hole binaries can be measured with the Laser Interferometer Space Antenna (LISA). By using complete waveforms including the inspiral, merger and ringdown portions of the signals, we find that LISA will have far greater precision than previous estimates for nonspinning mergers that ignored the merger and ringdown. Our analysis covers nonspinning waveforms with moderate mass ratios, q > or = 1/10, and total masses 10(exp 5) merger. In real-time observations, the later parts of the signal lead to significant improvements in sky-position precision in the last hours and even the final minutes of observation. For comparable mass systems with total mass M/M_{Sun} = approx. 10(exp 6), we find that the increased precision resulting from including the merger is comparable to the increase in signal-to-noise ratio. For the most precise systems under investigation, half can be localized to within O(10 arcmin), and 18% can be localized to within O(1 arcmin).

  13. Relative humidity impact on aerosol parameters in a Paris suburban area

    Directory of Open Access Journals (Sweden)

    H. Randriamiarisoa

    2006-01-01

    Full Text Available Measurements of relative humidity (RH and aerosol parameters (scattering cross section, size distributions and chemical composition, performed in ambient atmospheric conditions, have been used to study the influence of relative humidity on aerosol properties. The data were acquired in a suburban area south of Paris, between 18 and 24 July 2000, in the framework of the 'Etude et Simulation de la Qualité de l'air en Ile-de-France' (ESQUIF program. According to the origin of the air masses arriving over the Paris area, the aerosol hygroscopicity is more or less pronounced. The aerosol chemical composition data were used as input of a thermodynamic model to simulate the variation of the aerosol water mass content with ambient RH and to determine the main inorganic salt compounds. The coupling of observations and modelling reveals the presence of deliquescence processes with hysteresis phenomenon in the hygroscopic growth cycle. Based on the Hänel model, parameterisations of the scattering cross section, the modal radius of the accumulation mode of the size distribution and the aerosol water mass content, as a function of increasing RH, have been assessed. For the first time, a crosscheck of these parameterisations has been performed and shows that the hygroscopic behaviour of the accumulation mode can be coherently characterized by combined optical, size distribution and chemical measurements.

  14. Impact of maternal and neonatal factors on parameters of hematopoietic potential in umbilical cord blood

    Science.gov (United States)

    Al-Deghaither, Sara Y.

    2015-01-01

    Objectives: To determine characteristics of laboratory parameters of hematopoietic potential in umbilical cord blood and their association with maternal and neonatal factors. Methods: This prospective analysis was performed on 206 umbilical cord blood donations (50-200 ml) from King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia between January and September 2014. Samples were processed and analyzed for total nucleated cells (TNC’s), cluster designation (CD)45+, CD34+ counts, nucleated red blood cells (NRBCs) count, and viability testing. Results: Most of the study participants (63.6%) were on their first 3 deliveries and from women with age between 17 and 30 years (80.6%). The donated volume was 50.4-192.4 ml, TNCs ranged from 500.2×106 to 9430.3 ×106 cells, and CD34+ cells ranged from 1.25×106 to 12.82×106/unit. The volume was positively affected by bigger birth weight of the baby (pumbilical cord blood, several maternal and neonatal factors should be considered, as younger maternal age, neonatal birth weight >3300 grams, larger placental size, and first or second-born babies, were shown to be associated with higher TNCs, CD34+, CD45+, NRBCs, and viability. PMID:25987113

  15. Impact of High-Carbohydrate Diet on Metabolic Parameters in Patients with Type 2 Diabetes

    Science.gov (United States)

    Jung, Chan-Hee; Choi, Kyung Mook

    2017-01-01

    In patients with type 2 diabetes mellitus (T2DM), whether dietary carbohydrates have beneficial or detrimental effects on cardiometabolic risk factors has drawn attention. Although a high-carbohydrate (HC) diet and a low-carbohydrate (LC) diet have gained popularity for several decades, there is scarce review focusing on the effects of HC diet on glucose, lipids and body weight in patients with T2DM. In this review, we examined recently-published literature on the effects of HC diets on metabolic parameters in T2DM. HC diets are at least as effective as LC diets, leading to significant weight loss and a reduction in plasma glucose, HbA1c and low density lipoprotein-cholesterol (LDL-C) levels. The major concern is that HC diets may raise serum triglyceride levels and reduce high density lipoprotein-cholesterol (HDL-C) levels, increasing the risk of cardiovascular disease. However, these untoward effects were not a persistent consequence and may be ameliorated with the consumption of a low glycemic index (GI)/low glycemic load (GL) and high fiber. Carbohydrate intake should be individualized, and low caloric intake remains a crucial factor to improve insulin sensitivity and reduce body weight; however, an HC diet, rich in fiber and with a low GI/GL, may be recommendable in patients with T2DM. PMID:28338608

  16. The impact of parameters of store illumination on food shopper response.

    Science.gov (United States)

    Berčík, Jakub; Horská, Elena; Wang, Regina W Y; Chen, Ying-Chun

    2016-11-01

    Customer behavior in sales areas is strongly influenced by the perception of surroundings and feelings of well-being. By using dynamic retail solutions of basic, accent and dramatic lighting it is possible to attract attention, create a unique in-store environment and give customers a reason to stay and return to the store. The simplest and also the most successful method to reach customer attention in food selection (buying) process is through eye-catchingly illuminated visuals of products. Visual senses has evolved to top ranks in the sensory hierarchy, therefore visual stimuli have a tendency to overcome all other senses. The paper deals with a comprehensive interdisciplinary research of the influence of light and color on the emotional state of consumers (valence) on the food market. It integrates the measurement of light intensity, color temperature or emitted color spectrum in grocery stores, recognition of emotional response and the time of its occurrence among respondents due to different lighting types and color in simulated laboratory conditions. The research is focused on accent lighting in the segment of fresh unpackaged food. Using a mobile 16-channel electroencephalograph (EEG equipment) from EPOC company and a mini camera we observed the response time and the emotional status (valence), in order to reveal true consumer preferences in different lighting conditions (color temperature and color rendering index) and their non-traditional color (yellow, purple, red, blue and green) for the selected food type. The paper suggests possibilities for rational combination of the effective, efficient and energy-saving accent lighting, by which the retailer can achieve not only an eye-catching and attractive presentation of merchandised products, but also significant savings within operating their stores. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Mental Simulation of Painful Situations Has an Impact on Posture and Psychophysiological Parameters

    Directory of Open Access Journals (Sweden)

    Thierry Lelard

    2017-11-01

    Full Text Available Embodiment is made possible by the ability to imagine ourselves in a particular situation (mental simulation. Postural changes have been demonstrated in response to painful situations, but the effect of an implicit instruction has not been studied. The present study was designed to record differential responses according to whether or not subjects were instructed to imagine themselves in a painful or non-painful situation. Painful stimuli and instructions to mentally simulate the displayed situation were hypothesized to induce postural changes that could be demonstrated by changes in the center of pressure (COP trajectory compared to viewing the same stimuli with no instructions. We hypothesized that mental simulation of a painful situation would induce embodiment of the emotional situation as reflected by posterior displacement of the COP and physiological responses as compared to passive observation of the same visual scene. Thirty-one subjects participated in this study while standing quietly on a posturographic platform with presentation of visual stimuli depicting scenes defining three experimental conditions (painful, non-painful and neutral situations for 12 s. Physiological measurements [heart rate (HR and electrodermal activity] and postural responses (COP displacements were recorded in response to the stimuli with or without instructions to imagine themselves in the situation. Time-course analyses (1 s sliding window were conducted for several postural parameters, HR and electrodermal response. An interaction effect (instruction × stimuli × time demonstrated that mental simulation induced posterior displacement of the mean position of the COP at different times during presentation of visual stimuli (4 s; 9–12 s. An effect of instruction was reported for HR (HR was higher in the mental simulation condition, while a stimulation effect was reported only for HR (lower for painful stimuli than for non-painful stimuli. The results of

  18. Transfusion treatment impact in the improvement of haematological parameters in patients with gastrointestinal bleeding

    Directory of Open Access Journals (Sweden)

    Iliriane Bunjaku

    2012-04-01

    Full Text Available Introduction: Transfusion treatment (TT is necessary in patients with gastrointestinal bleeding (GIB for lost blood substitution. This study was aimed at assessing the changes in haematological parameters  (hemoglobin, hematocrit, red blood cell count, white cell count, platelet count and prothrombin time before and after TT in anaemic patients with GIB in order to analyse the effect of this treatment.Methods: There have been included 293 patients with GIB (the average age was 57.3, ranged from 18-89 years who were treated with TT at the Internal Clinic at the University Clinical Center Prishtina during oneyear period. Data for applied blood product and results of the coagulation screen (PT were collected from the Kosovo’s Blood Transfusion Center (KBTC.Results: TT has been carried out in 404 episodes, with 714 units of concentrated red blood cells (78.6%, 189 units of fresh frozen plasma (20.8% and concentrated platelets (0.6%, with an average dose 3.1 fortransfunded patients. Average values of Hb before and after TT were 71.8 g/L and 81.4 g/L, respectively; while the average values of hematocrite before and after TT were 22.9% and 25.6%, respectively. The averageerythrocytes count before TT was 2.6 respectively after treatment 2.8(pConclusions: Having in mind difficult clinical and unsustainable situation in patients with gastrointestinal bleeding, the Transfusion Treatment resulted in the considerable improvement of the specific blood indicators.

  19. Stacked Weak Lensing Mass Calibration: Estimators, Systematics, and Impact on Cosmological Parameter Constraints

    Energy Technology Data Exchange (ETDEWEB)

    Rozo, Eduardo; /U. Chicago /Chicago U., KICP; Wu, Hao-Yi; /KIPAC, Menlo Park; Schmidt, Fabian; /Caltech

    2011-11-04

    When extracting the weak lensing shear signal, one may employ either locally normalized or globally normalized shear estimators. The former is the standard approach when estimating cluster masses, while the latter is the more common method among peak finding efforts. While both approaches have identical signal-to-noise in the weak lensing limit, it is possible that higher order corrections or systematic considerations make one estimator preferable over the other. In this paper, we consider the efficacy of both estimators within the context of stacked weak lensing mass estimation in the Dark Energy Survey (DES). We find that the two estimators have nearly identical statistical precision, even after including higher order corrections, but that these corrections must be incorporated into the analysis to avoid observationally relevant biases in the recovered masses. We also demonstrate that finite bin-width effects may be significant if not properly accounted for, and that the two estimators exhibit different systematics, particularly with respect to contamination of the source catalog by foreground galaxies. Thus, the two estimators may be employed as a systematic cross-check of each other. Stacked weak lensing in the DES should allow for the mean mass of galaxy clusters to be calibrated to {approx}2% precision (statistical only), which can improve the figure of merit of the DES cluster abundance experiment by a factor of {approx}3 relative to the self-calibration expectation. A companion paper investigates how the two types of estimators considered here impact weak lensing peak finding efforts.

  20. The impact of material attributes and process parameters on the micronisation of lactose monohydrate.

    Science.gov (United States)

    Shariare, M H; de Matas, M; York, P; Shao, Q

    2011-04-15

    Dry powder inhalers (DPIs), which are important medicines for drug delivery to the lungs, require drug particles in the respirable size range of 1-6 μm for optimal lung deposition. Drugs administered by the oral route also derive benefit from particles in this size range owing to their large surface area to volume ratio, which provides potential for rapid dissolution. Micronisation used in the production of particles, however often leads to heterogeneous product containing mechanically activated surfaces with amorphous content. This study was therefore carried out to evaluate the effect of particle properties of three grades of lactose monohydrate, with sizes above and below the brittle-ductile transition (dcrit) and their interaction with process variables on the quality of micronised material. Following an experimental design, the impact of three factors (grinding pressure, injector pressure and feed rate) on the particulate attributes of micronised powders produced from the different size grades was assessed. Processing conditions were shown to be important determinants of powder properties only for the coarsest starting material. Ultrafine material was achieved by processing finer grade feed stock below dcrit. However the resultant product was more crystalline and transformed on heating to the anhydrous state with markedly reduced onset temperature with lower energy surfaces than powders produced from larger sized starting material. Thus the propensity for micronisation of lactose monohydrate can be altered through control of starting materials and optimal settings for process variables. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. The Impact Of Integrated Parameters In The Manga Local Mass-Metallicity Relation

    Science.gov (United States)

    Barrera-Ballesteros, Jorge K.

    2016-09-01

    We present the surface mass density - gas metallicity (Σ_*-Z) relation for more than 500,000 spatially-resolved star-forming regions from a sample of 617 disk galaxies included in the MaNGA survey. We find a tight relation between these local properties with higher metallicities as the surface density increases, resembling a scaled-down version of the relation found previously for their integrated counterparts. This relation expands over three orders of magnitude in the surface mass and a factor of 8 in metallicity. Our large sample allows us to study the impact of global properties in this local relation. In particular, we find that for most disk galaxies the Σ_*-Z relation does not depend on the total stellar mass. Even more, for a large fraction of our sample (log(M_*/M_{⊙}) > 9.2) the observed metallicity gradients are well reproduced by the mass density gradients and the Σ_*-Z relation. We also find that this relation does not change significantly within the range of redshifts span by our sample. Our results suggest as the predominant scenario for metal enrichment as gas been recycled locally at shorter timescales in comparison to other global processes such as gas accretion or outflows.

  2. Impact of the digitalisation of mammography on performance parameters and breast dose in the Flemish Breast Cancer Screening Programme.

    Science.gov (United States)

    Timmermans, Lore; De Hauwere, An; Bacher, Klaus; Bosmans, Hilde; Lemmens, Kim; Bleyen, Luc; Van Limbergen, Erik; Martens, Patrick; Van Steen, Andre; Mortier, Griet; Van Herck, Koen; Thierens, Hubert

    2014-08-01

    To investigate the impact of digitalisation on performance parameters and breast dose of the Flemish Breast Cancer Screening Programme. Both computed (CR) and direct radiography (DR) are compared with screen-film mammography (SFM). Data from 975,673 mammographic examinations were collected from units which underwent digitalisation from SFM to CR (41 units) or DR (72 units) in the period 2005-2011. Performance indicators were obtained by consulting the Screening Programme database. Phantom and patient dosimetry data were acquired from the physical technical quality assurance of the programme. Digitalisation induced no significant change in cancer detection rate (CDR), percentage of ductal carcinomas in situ and percentage of breast cancers smaller than 1 cm. A decrease in false-positive results and third readings was observed, which was a time-related observation. After digitalisation, positive predictive value (PPV) increased and recall rates decreased. Compared with SFM, an increase of 30% in mean glandular dose (MGD) was found for CR, while a similar change in the opposite direction was found for DR. No major differences in performance parameters after digitalisation were found. Transition of SFM to CR resulted in a higher MGD and associated lower detection-over-induction ratio (DIR), while the change to DR induced an improvement of DIR. • Performance parameters showed no major differences after digitalisation to CR or DR. • Transition from SFM to CR results in a higher mean glandular dose. • Transition from SFM to DR results in a lower mean glandular dose.

  3. Adherence to a pedometer-based physical activity intervention following kidney transplant and impact on metabolic parameters.

    Science.gov (United States)

    Lorenz, Elizabeth C; Amer, Hatem; Dean, Patrick G; Stegall, Mark D; Cosio, Fernando G; Cheville, Andrea L

    2015-06-01

    The majority of kidney transplant recipients die from cardiovascular events. Physical activity may be a modifiable risk factor for cardiovascular disease following transplant. The goal of our study was to examine adherence to a physical activity intervention following kidney transplant and its impact on metabolic parameters. All patients who received a kidney transplant at our center between 12/2010 and 12/2011 received usual care (n = 162), while patients transplanted between 12/2011 and 1/2013 received a 90-day pedometer-based physical activity intervention (n = 145). Metabolic parameters were assessed at four and 12 months post-transplant. Baseline demographics and clinical management were similar between cohorts. Adherence to the prescription was 36.5%. Patients in the physical activity cohort had lower systolic and diastolic blood pressure four months post-transplant compared to the usual care cohort (122 ± 18 vs. 126 ± 16 mmHg, p = 0.049 and 73 ± 10 vs. 77 ± 9, p = 0.004) and less impaired fasting glucose (20.7% vs. 30.9%, p = 0.04). Twelve-month outcomes were not different between cohorts. Over one-third of our cohort adhered to a pedometer-based physical activity intervention following kidney transplant, and the intervention was associated with improved metabolic parameters. Further study of post-transplant exercise interventions and methods to optimize long-term adherence are needed. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. IMPACT OF 10 SESSIONS OF WHOLE BODY CRYOSTIMULATION ON AEROBIC AND ANAEROBIC CAPACITY AND ON SELECTED BLOOD COUNT PARAMETERS

    Directory of Open Access Journals (Sweden)

    Tomasz Dybek

    2012-01-01

    Full Text Available The systemic effect of low temperature suggests that sessions in a cryogenic chamber might improve athletes’ capacity as a standard element of training. Therefore the authors decided to evaluate the impact of 10 sessions of whole body cryostimulation (WBCT on aerobic and anaerobic efficiency as well as on selected blood count parameters. The study group included 32 volunteers – 16 women and 16 men. The volunteers underwent 10 sessions of WBCT in a cryogenic chamber. Blood samples (RBC, WBC, PLT, HGB, HCT were taken, and aerobic and anaerobic efficiency and lactate concentration in capillary blood were measured before the first session and one day after the last one. No significant differences were observed in values of aerobic capacity after 10 sessions of WBCT. There was a rising trend in men and a declining trend in women. The lactate concentration did not differ significantly before and after WBCT. A slight rise in aerobic and anaerobic threshold was observed in men, while in women the values slightly fell. The Wingate test showed no significant differences in results before and after cryostimulation. Only the TOBT was significantly shorter in men (6.12±1.49 vs 3.79±1.14 s. The WBCT sessions resulted in a significant rise of the haematological parameters both in women and men, excluding HCT, which showed a statistically insignificant rise. Ten sessions of whole body cryostimulation did not affect aerobic or anaerobic capacity in the tested group, although it improved the blood count parameters.

  5. Indoor air quality in the Karns research houses: baseline measurements and impact of indoor environmental parameters on formaldehyde concentrations

    International Nuclear Information System (INIS)

    Matthews, T.G.; Fung, K.W.; Tromberg, B.J.; Hawthorne, A.R.

    1985-12-01

    Baseline indoor air quality measurements, a nine-month radon study, and an environmental parameters study examining the impact of indoor temperature (T) and relative humidity (RH) levels on formaldehyde (CH 2 O) concentrations have been performed in three unoccupied research homes located in Karns, Tennessee. Inter-house comparison measurements of (1) CH 2 O concentration, (2) CH 2 O emission rates from primary CH 2 O emission sources, (3) radon and radon daughter concentrations, and (4) air exchange rates indicate that the three homes are similar. The results of the nine-month radon study indicate indoor concentrations consistently below the EPA recommended level of 4 pCi/L. Evidence was found that crawl-space concentrations may be reduced using heat pump systems whose outdoor units circulate fresh air through the crawl-space. The modeled results of the environmental parameters study indicate approximate fourfold increases in CH 2 O concentrations from 0.07 to 0.27 ppM for seasonal T and RH conditions of 20 0 C, 30% RH and 29 0 C, 80% RH, respectively. Evaluation of these environmental parameters study data with steady-state CH 2 O concentration models developed from laboratory studies of the environmental dependence of CH 2 O emissions from particleboard underlayment indicate good correlations between the laboratory and field studies

  6. Spatiotemporal impacts of LULC changes on hydrology from the perspective of runoff generation mechanism using SWAT model with evolving parameters

    Science.gov (United States)

    Li, Y.; Chang, J.; Luo, L.

    2017-12-01

    It is of great importance for water resources management to model the truly hydrological process under changing environment, especially under significant changes of underlying surfaces like the Wei River Bain (WRB) where the subsurface hydrology is highly influenced by human activities, and to systematically investigate the interactions among LULC change, streamflow variation and changes in runoff generation process. Therefore, we proposed the idea of evolving parameters in hydrological model (SWAT) to reflect the changes in physical environment with different LULC conditions. Then with these evolving parameters, the spatiotemporal impacts of LULC changes on streamflow were quantified, and qualitative analysis was conducted to further explore how LULC changes affect the streamflow from the perspective of runoff generation mechanism. Results indicate the following: 1) evolving parameter calibration is not only effective but necessary to ensure the validity of the model when dealing with significant changes in underlying surfaces due to human activities. 2) compared to the baseline period, the streamflow in wet seasons increased in the 1990s but decreased in the 2000s. While at yearly and dry seasonal scales, the streamflow decreased in both two decades; 3) the expansion of cropland is the major contributor to the reduction of surface water component, thus causing the decline in streamflow at yearly and dry seasonal scales. While compared to the 1990s, the expansions of woodland in the middle stream and grassland in the downstream are the main stressors that increased the soil water component, thus leading to the more decline of the streamflow in the 2000s.

  7. Impact of Seminal Plasma Trace Elements on Human Sperm Motility Parameters.

    Science.gov (United States)

    Hashemi, Mohammad Mostakhdem; Behnampour, Nasser; Nejabat, Mojgan; Tabandeh, Afsaneh; Ghazi-Moghaddam, Behrouz; Joshaghani, Hamid Reza

    2018-03-01

    Human seminal plasma contains a variety of macro and trace elements including magnesium (Mg), copper (Cu), zinc (Zn), and iron (Fe) that have essential roles in normal functioning of semen and its quality. The imbalance of these elements has been reported in several pathologic and male infertility disorders. Therefore, this study aimed to determine the levels of these elements in seminal plasma samples, their relationships with each other and their impact on sperm motility. Overall, 192 males (96 normospermic and 96 asthenospermic males) were enrolled in the study. Semen samples were collected by masturbation and computer-assisted/aided semen analysis of sperm motility was performed. The samples were centrifuged and seminal levels of Mg, Cu, Zn and Fe were measured using atomic absorption spectroscopy. The levels of Zn did not differ between the two groups, while the levels of Mg, Cu, and Fe were significantly higher in normospermic males. Fe showed a positive correlation with Mg and Cu in asthenospermic group. However, a negative relationship was found between Mg and Fe levels and between Mg and sperm concentration in the normospermic group. Fe levels were higher in the normospermic group compared to the asthenospermic group. Nevertheless, increased Fe levels caused a decrease in most of sperm motility fractions. Elements play major roles in male fertility and directly affect sperm quality. According to the results of this study, the levels of Zn do not affect the sperm quality and motility, while Fe, Cu and Mg are decreased in males with sperm motility problems. Nevertheless, Fe levels can adversely affect sperm motility in normospermic men.

  8. Impact of Roux-en-Y Gastric Bypass on Metabolic Syndrome and Insulin Resistance Parameters

    Science.gov (United States)

    Gestic, Martinho Antonio; Utrini, Murillo Pimentel; Machado, Ricardo Rossetto; Geloneze, Bruno; Pareja, José Carlos; Chaim, Elinton Adami

    2014-01-01

    Abstract Background: Metabolic syndrome (MetS) is a complex association of clustering metabolic factors that increase risk of type 2 diabetes mellitus (T2DM) and cardiovascular disease. Surgical treatment has become an important tool to achieve its control. The aim of this study was to evaluate the impact of Roux-en-Y gastric bypass (RYGB) on MetS and its individual components, clinical characteristics, and biochemical features. Subjects and Methods: The study is a retrospective cohort of 96 subjects with MetS who underwent RYGB and were evaluated at baseline and after surgery. Clinical and biochemical features were analyzed. Results: After surgery, significant rates of resolution for MetS (88.5%), T2DM (90.6%), hypertension (85.6%), and dyslipidemias (54.2%) were found. Significant decreases in levels of fasting glucose, fasting insulin, hemoglobin A1c, low-density lipoprotein, and triglycerides and an increase in high-density lipoprotein level were also shown. The decrease in insulin resistance evaluated by homeostasis model assessment (HOMA-IR) was consistent. MetS resolution was associated with postoperative glycemic control, decreases in levels of fasting glucose, hemoglobin A1c, HOMA-IR, and triglycerides and in antihypertensive usage, and percentage weight loss. Conclusions: This study found high rates of resolution for MetS, T2DM, hypertension, and dyslipidemias after RYGB in obese patients. This finding was consistent with current literature. Hence RYGB should be largely indicated for this group of subjects as it is a safe and powerful tool to achieve MetS control. PMID:24299427

  9. Evaluating the impact of handling and logger attachment on foraging parameters and physiology in southern rockhopper penguins.

    Directory of Open Access Journals (Sweden)

    Katrin Ludynia

    Full Text Available Logger technology has revolutionised our knowledge of the behaviour and physiology of free-living animals but handling and logger attachments may have negative effects on the behaviour of the animals and their welfare. We studied southern rockhopper penguin (Eudyptes chrysocome females during the guard stage in three consecutive breeding seasons (2008/09-2010/11 to evaluate the effects of handling and logger attachment on foraging trip duration, dive behaviour and physiological parameters. Smaller dive loggers (TDRs were used in 2010/11 for comparison to larger GPS data loggers used in all three seasons and we included two categories of control birds: handled controls and PIT control birds that were previously marked with passive integrative transponders (PITs, but which had not been handled during this study. Increased foraging trip duration was only observed in GPS birds during 2010/11, the breeding season in which we also found GPS birds foraging further away from the colony and travelling longer distances. Compared to previous breeding seasons, 2010/11 may have been a period with less favourable environmental conditions, which would enhance the impact of logger attachments. A comparison between GPS and TDR birds showed a significant difference in dive depth frequencies with birds carrying larger GPS data loggers diving shallower. Mean and maximum dive depths were similar between GPS and TDR birds. We measured little impact of logger attachments on physiological parameters (corticosterone, protein, triglyceride levels and leucocyte counts. Overall, handling and short-term logger attachments (1-3 days showed limited impact on the behaviour and physiology of the birds but care must be taken with the size of data loggers on diving seabirds. Increased drag may alter their diving behaviour substantially, thus constraining them in their ability to catch prey. Results obtained in this study indicate that data recorded may also not represent their

  10. White popular (Populus alba L.) - Litter impact on chemical and biochemical parameters related to nitrogen cycle in contaminated soils

    Energy Technology Data Exchange (ETDEWEB)

    Ciadamidaro, L.; Madejon, P.; Cabrera, F.; Madejon, E.

    2014-06-01

    Aim of study: The aim of this study was to determine the effect of litter from Populus alba on chemical and biochemical properties related to the N cycle in soils with different pH values and trace element contents. We hypothesized that this litter would influence several parameters related to the N cycle and consequently to soil health. Area of study: we collected two reforested contaminated soils of different pH values (AZ pH 7.23 and DO pH 2.66) and a non-contaminated soil (RHU pH 7.19). Materials and methods: Soil samples were placed in 2,000 cm{sup 3} microcosms and were incubated for 40 weeks in controlled conditions. Each soil was mixed with its corresponding litter, and soils without litter were also tested for comparison. Ammonium (NH{sub 4}{sup 4}+-N) and nitrate (NO{sub 3}{sup -} -N) content, potential nitrification rate (PNR), microbial biomass nitrogen (MBN), protease activity, and several chemical properties such as pH, available trace element concentrations (extracted with 0.01 M CaCl{sub 2}) were determined at different times of incubation. Main results: Values of available trace elements did not vary during the incubation and were always higher in acid soil. In neutral soils litter presence increased values of Kjeldahl-N, NO{sub 3} –-N content, potential nitrification rate (PNR), microbial biomass nitrogen (MBN) and protease activity. Presence of trace elements in neutral soils did not alter the parameters studied. However, acidic pH and high content of available trace elements strongly affected NH{sub 4}{sup +}-N and NO{sub 3}{sup -} -N, microbial biomass N and protease activity. Research highlights: Our results showed the negative effect of the acidity and trace element availability in parameters related with the N-cycle. (Author)

  11. White poplar (Populus alba L. - Litter impact on chemical and biochemical parameters related to nitrogen cycle in contaminated soils

    Directory of Open Access Journals (Sweden)

    Paula Madejon

    2014-04-01

    Full Text Available Aim of study: The aim of this study was to determine the effect of litter from Populus alba on chemical and biochemical properties related to the N cycle in soils with different pH values and trace element contents. We hypothesized that this litter would influence several parameters related to the N cycle and consequently to soil health.Area of study: we collected two reforested contaminated soils of different pH values (AZ pH 7.23 and DO pH = 2.66 and a non-contaminated soil (RHU pH 7.19.Materials and methods: Soil samples were placed in 2,000 cm3 microcosms and were incubated for 40 weeks in controlled conditions. Each soil was mixed with its corresponding litter, and soils without litter were also tested for comparison. Ammonium (NH4+-N and nitrate (NO3–-N content, potential nitrification rate (PNR, microbial biomass nitrogen (MBN, protease activity, and several chemical properties such as pH, available trace element concentrations (extracted with 0.01 M CaCl2 were determined at different times of incubation.Main results: Values of available trace elements did not vary during the incubation and were always higher in acid soil. In neutral soils litter presence increased values of Kjeldahl-N, NO3–-N content, potential nitrification rate (PNR, microbial biomass nitrogen (MBN and protease activity. Presence of trace elements in neutral soils did not alter the parameters studied. However, acidic pH and high content of available trace elements strongly affected NH4+-N andNO3–-N, microbial biomass N and protease activity.Research highlights: Our results showed the negative effect of the acidity and trace element availability in parameters related with the N-cycle.Key words: microbial biomass N; protease activity; soil pH; N mineralization; nitrification; phytoremediation.

  12. Impact of tocilizumab therapy on immunological parameters in patients with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Anastasia Sergeyevna Avdeyeva

    2012-01-01

    Full Text Available Objective: to evaluate the impact of tocilizumab (TCZ therapy on the level of acute-phase indicators, autoantibodies, and immunoglobulins (Ig G, M, and A after 2, 4, 8, 12, and 24 weeks as compared to the clinical efficacy of TCZ using DAS 28, SDAI, and CDAI scores and to reveal the immunological predictors of effective TCZ therapy. Subjects and methods. Forty-two patients with rheumatoid arthritis (RA who had received 6 TCZ infusions in an intravenous dose of 8 mg/kg at a 4-week interval during stable therapy with disease-modifying antirheumatic drugs (DMARDs and glucocorticosteroids were examined. Erythrocyte sedimentation rate (ESR was determined by the Westergren method; the levels of C-reactive protein (CRP, IgM rheumatoid factor (RF, IgG, IgM, and IgA were measured by a nephelometric method; the content of anti-cyclic citrullinated peptide (anti-CCP antibodies was estimated by an electrochemiluminescence technique. Results. In the respondents to TCZ therapy, the baseline Me values [25 th; 75 th percentiles] were 6.44 (5.87; 7.04 for DAS 28; 41.5 (32; 53 for SDAI; and 36.4 (19.2; 62.7 mg for CRP; 262.0 (95.3; 663.0 IU/l for IgM RF; 342.5 (106.9; 789.9 IU/ml for IgA RF; 366.8 (76.9; 500.0 for anti-CCP antibodies; 770.5 (190.7; 2393.1 IU/ml for anti-modified citrullinated vimentin (anti-MCV antibodies; 16.1 (12.9; 21.1 g/l for IgG; 2.07 (1.68; 2.63 g/l for IgM; 4.19 (3.38; 5.71 g/l for IgA. At week 2 of TCZ therapy, there was a reduction in the levels of CRP to 0.5 (0.3; 1 mg/l, IgM RF to 191.5 (45.6; 507.5 IU/ml, IgA RF to 225.8 (74.2; 547.4 IU/ml; at week 4, there were decreases in anti-MCV titers to 312.15 (81.2; 925.5 IU/ml, which remained until week 24 (p < 0.01. By week 24 of therapy, there were falls of IgG to 9.41 (8.14; 11.8 g/l, IgM to 1.12 (0.89; 1.94 g/l, IgA to 2.15 (1.73; 2.73 g/l (р < 0.01; however, their mean level as a whole remained to be in the normal range. The anti-MCV-positive patients with RA more frequently achieved a

  13. The impact of physiotherapy on bodily parameters and load tolerance in obese patients - The clinical application of the International Classification of Functioning, Disability and Health in obese patients

    OpenAIRE

    Šimonová, Anna

    2015-01-01

    BACHELOR THESIS ABSTRACT Author's first name and surname: Anna Šimonová Bachelor thesis supervizor: Bc. Alena Homolková Oponent: Title of bachelor thesis: The impact of physiotherapy on bodily parameters and load tolerance in obese patients Abstract: This bachelor thesis deals with the impact of physiotherapy on bodily parameters and load tolerance in obese patients. It also concerns with the clinical application of the International Classification of Functioning, Disability and Health (ICF) ...

  14. Impact of dietary plane of energy during the dry period on lipoprotein parameters in the transition period in dairy cattle.

    Science.gov (United States)

    Newman, A; Mann, S; Nydam, D V; Overton, T R; Behling-Kelly, E

    2016-02-01

    The high energy demands of dairy cows during the transition period from late gestation into early lactation can place them at an increased risk for the development of metabolic and infectious diseases. Modification of the dry period diet has been investigated as a preventive means to minimize the detrimental aspects of metabolic shifts during the transition period. Studies investigating the impact of dry period diet on lipid parameters during the transition period have largely focused on markers of lipolysis and ketogenesis. Total cholesterol declines during the periparturient period and increases in early lactation. The impact total energy in the dry period diet has on the ability of the cow to maintain total serum cholesterol, as well as its natural high-density lipoprotein-rich status, during this metabolically challenging window is not clear. The impact of lipoproteins on inflammation and immune function may have a clinical impact on the cow's ability to ward off production-related diseases. In this study, we hypothesized that the provision of adequate, but not excessive, total metabolizable energy, would better allow the cow to maintain total cholesterol and a higher relative proportion of HDL throughout the transition period. Cows were allocated to one of three dry period dietary treatment groups following a randomized block design. Total serum triglycerides, cholesterol and lipoprotein fractions were measured on a weekly basis from approximately 7 weeks pre-calving to 6 weeks post-calving. The cows on the high energy diet maintained total serum cholesterol as compared to the cows provided a lower energy diet, but there was no significant increase in the LDL fraction of lipoproteins between diet treatment groups. Journal of Animal Physiology and Animal Nutrition © 2015 Blackwell Verlag GmbH.

  15. Impact parameter analysis of proton-proton elastic and inelastic interactions at 360 GeV/c

    International Nuclear Information System (INIS)

    Banerjee, S.; Ragavan, R.; Bailly, J

    1987-01-01

    Data obtained with the European Hybrid Spectrometer on the proton-proton elastic scattering at 360 GeV/c are presented. The differential cross sections of elastic and inelastic pp-interactions are studied as a function of the impact parameter. The results are compared to those obtained at other energies. They are interpreted in the framework of a simple geometrical Monte-Carlo model of inelastic collisions considering protons as composite particles having a definite effective radius with valence quarks inside. The shape of the inelastic overlap function is well reproduced for both pp- and π + p-interactions. The effective radii of the proton and pion as well as of the valence quarks are estimated for inelastic interactions. The model calculations indicate an increase of the effective radii both of protons and valence quarks and an increase of the proton opacity with increasing energy

  16. Research on the Impact of Amplitude of Vibrations on Electrical Parameters of Vibroarc Weld Overlay in Argon

    Directory of Open Access Journals (Sweden)

    Nikolov Mitko Ivanov

    2015-06-01

    Full Text Available The research is taken on the vibroarc welding apparatus ENTON-60 equipped with an axial non-inertial vibrator in argon shield. The criteria used for assessing the flow of the electric arc process and the formation of weld overlay clad surfaces are: short circuit voltage, voltage at the start of arc combustion, short circuit amperage, and amperage at the end of arc combustion. Wire electrode‘s vibrating frequency is considered as an input variable of the cybernetic model. It has been found that amplitude of vibrations has a significant impact on the vibroarc process - voltage parameters and welding current ratio, as the minimum amperage of short circuit and the lowest voltage at the start of arc combustion is realized at 2 mm amplitude of vibrations.

  17. Luminescence model with quantum impact parameter for low energies; Modelo de luminiscencia con parametro de impacto cuantico para bajas energias

    Energy Technology Data Exchange (ETDEWEB)

    Cruz G, H.S.; Michaelian, K.; Galindo U, S.; Martinez D, A.; Belmont M, E. [Instituto Nacional de Investigaciones Nucleares, Carretera Mexico- Toluca Km. 36.5, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    2000-07-01

    The analytical model of induced light production in scintillator materials by energetic ions proposed by Michaelian and Menchaca (M-M) adjusts very well the luminescence substance data in a wide energy interval of the incident ions (10-100 MeV). However at low energies, that is, under to 10 MeV, the experimental deviations of the predictions of M-M model, show that the causes may be certain physical effects, all they important at low energies, which were not considered. We have modified lightly the M-M model using the basic fact that the Quantum mechanics gives to a different limit for the quantum impact parameter instead of the classic approximation. (Author)

  18. Justification of Selecting Ultrasonic Testing Parameters for Bundle and Impact Damage Detection in Carbon-Fiber Constructions

    Directory of Open Access Journals (Sweden)

    M. V. Grigoriev

    2015-01-01

    Full Text Available Features of manufacturing process and use of carbon fibre-reinforced plastics (CFRP define specific types of only their defects. Furthermore, the CFRP structure material and its properties considerably differ from those of the metal materials. Therefore, a relevant task is to conduct research to justify the selection of the ultrasonic testing parameters of these materials.Optimal parameters and recommendations on quality control of such materials were grounded in the course of experimental studies on samples made from the UTR1000-12-400P carbon fabric, based on the T700GC-12K yarn and the T-31 epoxy binder, filled with artificial defects to imitate the bundles of different size and the impact damage.It is shown that with increasing frequency of the ultrasonic oscillation propagating in the samples there is an increase both in damping and in SNR for artificial defects. In other words, on the one hand, the lower is the oscillation frequency, the less is a damping effect, but, on the other one, the higher is the frequency, the higher is the sensitivity control. It was found that the optimum frequencies for the ultrasonic test of CFRP are those in the vicinity of 5 MHz.Furthermore, to detect the small-sized defects it is advised to use an ultrasonic beam focus, which can be achieved using phased arrays.The most optimal method of ultrasonic testing to search for impact damage is a mirrorshadow method, which is based on the measurement of the amplitude of the bottom echo signal. It is shown that the amplitude of the bottom echo signal in defect-free zone is, in average, 14 dB higher than in the area with shock damage.

  19. Impact of educational group strategy to improve clinical and glycemic parameters in individuals with diabetes and hypertension

    Directory of Open Access Journals (Sweden)

    Danielli Teixeira Lima Favaro

    Full Text Available Objective.To evaluate the impact of an educational group strategy to improve clinical and glycemic parameters in individuals with diabetes and hypertension. Methods. This descriptive prospective study included 172 individuals living in São José do Rio Preto-SP, Brazil, who were enrolled in a well-integrated educational group called HIPERDIA (Record System for Follow-up of Hypertensive and Diabetic Individuals coordinated by a qualified multidisciplinary team. We analyzed sociodemographic, anthropometric, clinical, and laboratory data. Data were collected in the first, fifth, and eighth meeting of the educational group. Results. A total of 68.6% of patients were women, 85.4% were white, 64.0% had an incomplete basic education, 47.7% were retired, 79.7% had been diagnosed with diabetes for 6 or more years, 9.9% were smokers, and 9.9% used alcohol. Individuals' diastolic blood pressure decreased between the fifth and eighth meeting (p<0.05. Between the first and fifth meeting, both fasting glucose levels (p<0.05 and glycated hemoglobin decreased; the latter continue to drop at the fifth and eighth meetings (p<0.001. Anthropometric parameters remained unchanged. Conclusion. The results suggest that an educational group strategy is favorable for controlling diabetes mellitus and hypertension.

  20. The impact of educational intervention on physical activity, nutrition and laboratory parameters in type II diabetic patients.

    Science.gov (United States)

    Maheri, Aghbabak; Asnaashari, Maryam; Joveini, Hamid; Tol, Azar; Firouzian, Ali Asghar; Rohban, Alireza

    2017-04-01

    Diabetes is one of the most common chronic diseases that is now widely spread around the world, and day by day the number of patients is increasing. The purpose of this study was to determine the impact of educational intervention on physical activity, nutrition and laboratory parameters in type 2 diabetic patients. This semi-experimental study was performed from March to October 2015 on 100 patients with type 2 diabetes who referred to the Niknejad health center. The type of sampling was simple random. Data were collected using a questionnaire including demographic questions, assessment of nutritional status and physical activity, history of diabetes, physical measurements and laboratory parameters of patients. Data were analyzed using SPSS 16, and descriptive and analytical tests (paired-samples t-test) and the results were significant at the level of (pintervention, while the variables of FBS level (pintervention. According to the findings of this study, to improve BMI, fish intake, type of oil consumption and also increased daily fruit and vegetable intake in these patients, a variety of educational-supportive interventions are recommended.

  1. Nonlinearly combined impacts of initial perturbation from human activities and parameter perturbation from climate change on the grassland ecosystem

    Directory of Open Access Journals (Sweden)

    G. Sun

    2011-11-01

    Full Text Available Human activities and climate change are important factors that affect grassland ecosystems. A new optimization approach, the approach of conditional nonlinear optimal perturbation (CNOP related to initial and parameter perturbations, is employed to explore the nonlinearly combined impacts of human activities and climate change on a grassland ecosystem using a theoretical grassland model. In our study, it is assumed that the initial perturbations and parameter perturbations are regarded as human activities and climate change, respectively. Numerical results indicate that the climate changes causing the maximum effect in the grassland ecosystem are different under disparate intensities of human activities. This implies the pattern of climate change is very critical to the maintenance or degradation of grassland ecosystem in light of high intensity of human activities and that the grassland ecosystem should be rationally managed when the moisture index decreases. The grassland ecosystem influenced by the nonlinear combination of human activities and climate change undergoes abrupt change, while the grassland ecosystem affected by other types of human activities and climate change fails to show the abrupt change under a certain range of perturbations with the theoretical model. The further numerical analyses also indicate that the growth of living biomass and the evaporation from soil surface shaded by the wilted biomass may be crucial factors contributing to the abrupt change of the grassland equilibrium state within the theoretical model.

  2. Impact of magnetic field parameters and iron oxide nanoparticle properties on heat generation for use in magnetic hyperthermia

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Rhythm R. [Department of Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, AL (United States); Davis, Todd P.; Glover, Amanda L.; Nikles, David E. [Department of Chemistry, The University of Alabama, Tuscaloosa, AL (United States); Brazel, Christopher S., E-mail: cbrazel@eng.ua.edu [Department of Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, AL (United States)

    2015-08-01

    Heating of nanoparticles (NPs) using an AC magnetic field depends on several factors, and optimization of these parameters can improve the efficiency of heat generation for effective cancer therapy while administering a low NP treatment dose. This study investigated magnetic field strength and frequency, NP size, NP concentration, and solution viscosity as important parameters that impact the heating efficiency of iron oxide NPs with magnetite (Fe{sub 3}O{sub 4}) and maghemite (γ-Fe{sub 2}O{sub 3}) crystal structures. Heating efficiencies were determined for each experimental setting, with specific absorption rates (SARs) ranging from 3.7 to 325.9 W/g Fe. Magnetic heating was conducted on iron oxide NPs synthesized in our laboratories (with average core sizes of 8, 11, 13, and 18 nm), as well as commercially-available iron oxides (with average core sizes of 8, 9, and 16 nm). The experimental magnetic coil system made it possible to isolate the effect of magnetic field parameters and independently study the effect on heat generation. The highest SAR values were found for the 18 nm synthesized particles and the maghemite nanopowder. Magnetic field strengths were applied in the range of 15.1–47.7 kA/m, with field frequencies ranging from 123 to 430 kHz. The best heating was observed for the highest field strengths and frequencies tested, with results following trends predicted by the Rosensweig equation. An increase in solution viscosity led to lower heating rates in nanoparticle solutions, which can have significant implications for the application of magnetic fluid hyperthermia in vivo. - Highlights: • Heating was tested in seven iron oxide nanoparticles for different magnetic fields. • Confirms an optimal nanoparticle size for heating that agrees with the literature. • Verifies Rosenweig's equation to predict the effect of field frequency on heating. • Reports reduced heating in high viscosity environments.

  3. Impacts of meteorological parameters and emissions on decadal, interannual, and seasonal variations of atmospheric black carbon in the Tibetan Plateau

    Directory of Open Access Journals (Sweden)

    Yu-Hao Mao

    2016-09-01

    Full Text Available We quantified the impacts of variations in meteorological parameters and emissions on decadal, interannual, and seasonal variations of atmospheric black carbon (BC in the Tibetan Plateau for 1980–2010 using a global 3-dimensional chemical transport model driven by the Modern Era Retrospective-analysis for Research and Applications (MERRA meteorological fields. From 1980 to 2010, simulated surface BC concentrations and all-sky direct radiative forcing at the top of the atmosphere due to atmospheric BC increased by 0.15 μg m−3 (63% and by 0.23 W m−2 (62%, respectively, averaged over the Tibetan Plateau (75–105°E, 25–40°N. Simulated annual mean surface BC concentrations were in the range of 0.24–0.40 μg m−3 averaged over the plateau for 1980–2010, with the decadal trends of 0.13 μg m−3 per decade in the 1980s and 0.08 in the 2000s. The interannual variations were −5.4% to 7.0% for deviation from the mean, 0.0062 μg m−3 for mean absolute deviation, and 2.5% for absolute percent departure from the mean. Model sensitivity simulations indicated that the decadal trends of surface BC concentrations were mainly driven by changes in emissions, while the interannual variations were dependent on variations of both meteorological parameters and emissions. Meteorological parameters played a crucial role in driving the interannual variations of BC especially in the monsoon season.

  4. Pinus sylvestris L. needle surface wettability parameters as indicators of atmospheric environment pollution impacts: Novel contact angle hysteresis methodology

    Science.gov (United States)

    Pogorzelski, Stanisław J.; Rochowski, Pawel; Szurkowski, Janusz

    2014-02-01

    An investigation of water contact angles (CAs), contact angle hysteresis (CAH) was carried out for 1-year to 4-year old needles (Pinus sylvestris) collected in urban (Gdansk) and rural (Karsin) locations using an original measuring technique based on the geometry of the drop on a vertical filament. Concentrations of air pollutants (SO2, NOx, C6H6, and suspended particular matter - SPM) currently considered to be most important in causing direct damage to vegetation were simultaneously monitored. A set of the surface wettability parameters: the apparent surface free energy γSV, adhesive film tension Π, work of adhesion WA, and spreading WS, were determined from CAH data using the approach developed by Chibowski (2003) to quantify the surface energetics of the needle substrata affected by aging and pollution impacts. This formalism relates the total apparent surface free energy of the solid γSV with only three measurable quantities: the surface tension of the probe liquid γLV and its advancing θA and receding θR contact angle hysteresis. Since CAH depends on the outermost wax layer surface roughness and spatial physicochemical heterogeneity of a solid surface, CA data were corrected using surface architecture profiles registered with confocal scanning laser microscopy. It was found that the roughness parameter r is significantly negatively correlated (R = -0.74) with the needle age (collected at Karsin). The needle surface aging process resulted in its surface hydrophilization (CA↓ and CAH↓ with γSV↑ and WA↑). A temporal evolution of the needles wettability was traced with the data point distribution in the 2D space of CAH plotted versus WS. The wettability parameters were closely correlated to pollutant concentrations as evidenced from Spearman's rank correlation procedure (R = 0.63-0.91; p biological systems.

  5. Biomechanics of the immediate impact of wearing a rigid thoracolumbar corset on gait kinematics and spatiotemporal parameters

    Directory of Open Access Journals (Sweden)

    Taiar Redha

    2018-01-01

    Full Text Available The corset support is a device classified as orthosis. It compensates a functional deficiency with means of protection, recovery, correction, maintenance, and support or contention. There are two types of orthosis 1 rest orthosis and 2 corrective orthosis. Rest orthosis maintains joints in a defined position to avoid deformities or to relieve a pain at joints. Corrective orthosis adjusts joint deformity either passively or actively. Corset is used in various pathological use, thoracic-lumbar fracture, scoliosis, Scheuermann’s disease or spinal dystrophy. The purpose of this study was 1 to determine the immediate impact of wearing a semi-rigid thoracolumbar corset, the Lombax® Dorso on gait kinematics and 2 spatiotemporal parameters in 6 adults. These parameters were recorded using the optoelectronic system Vicon® on treadmill gait subjects with and without corset for the comparison. The results showed that wearing a corset significantly decrease the rotation amplitudes of the scapular and pelvic girdles (p<0.05 in the frontal plane. The movement of the pelvis and hip in this same plane was decreased also when comparing with and without a corset effects (p<0.05. The corset significantly increased the range of flexion-extension of the hip during the gait cycle. At the conclusion of this study the discriminate parameters of wearing a corset was quantified. The results and in association with manufacturer will help to improve materials for better optimization support. Comparable perspectives and after improvement of materials will aim to experiment with patients on real daily life situation.

  6. Spatial and temporal variation in nutrient parameters in stream water in a rural-urban catchment, Shikoku, Japan: effects of land cover and human impact.

    Science.gov (United States)

    Mouri, Goro; Takizawa, Satoshi; Oki, Taikan

    2011-07-01

    Seasonal and spatial variations in major ion chemistry and isotope composition in the rural-urban catchment of the Shigenobu River were monitored to determine the influences of agricultural and urban sewage systems on water quality. Temporal patterns of biochemical oxygen demand (BOD), total nitrogen (TN), total phosphorus (TP), and suspended sediment (SS) were examined at four sites in the rural-urban catchment. Urban land cover, incorporating the effects of increased population, domestic water use, and industrial wastewater, was positively associated with increases in water pollution and was included as an important explanatory variable for the variations in all water quality parameters. Significant trends were found in each parameter. BOD concentrations ranged widely, and were high in urban regions, due to the presence of a waste water treatment plant. TN and SS showed various trends, but did not vary widely, unlike TP. TP concentrations varied greatly, with high concentrations in cultivated areas, due to fertilizer use. Local water quality management or geology could further explain some of the variations in water quality. Non-point-source pollution exhibited strong positive spatial autocorrelation, indicating that incorporating spatial dimensions into water quality assessment enhances our understanding of spatial patterns of water quality. Data from the Ministry of Land Infrastructure and Transport (MLIT) and Environment Ministry (EM) were used to investigate trends in land management. Stepwise regression analysis was used to test the correlation between specific management practises and substance concentrations in surface water and sediment. MLIT and EM data for 1981-2003 showed an increase in TN, TP, and SS concentrations in surface water. High levels of fertilizer in dormant sprays and domestic water use were associated with high pesticide concentrations in water and sediment. This paper presents a novel method of studying the environmental impact of

  7. Impact of Formulation Properties and Process Parameters on the Dispensing and Depositioning of Drug Nanosuspensions Using Micro-Valve Technology.

    Science.gov (United States)

    Bonhoeffer, Bastian; Kwade, Arno; Juhnke, Michael

    2017-04-01

    Flexible manufacturing processes with continuously adjustable dose strengths are considered particularly innovative and interesting for applications in personalized medicine, continuous manufacturing, or early drug development. A piezo-actuated micro-valve has been investigated for the dispensing and depositioning of drug nanosuspensions onto substrates to facilitate the manufacturing of solid oral dosage forms. The investigated micro-valve has been characterized regarding dispensing behavior, mass flow, accuracy, and robustness. The amount of dispensed drug compound during 1 dispensing event could be continuously adjusted from a few micrograms to several milligrams with high accuracy. Fluid properties, dispensing parameters of the micro-valve, and the resulting steady state mass flow could be correlated adequately for low-viscous drug nanosuspensions. High-speed imaging was used to investigate the dispensing behavior of the micro-valve regarding the evolution of the dispensed drug nanosuspension after ejection from the nozzle and the behavior during impact on flat and dry solid substrates. The experimentally determined breakup length of the dispensed liquid jet could be correlated with a semiempirical equation. From image sequences of the jet impact, We-Re phase diagrams could be established, providing a profound understanding and systematic guidance for the controlled depositioning of the entire dispensed drug nanosuspension onto the substrate. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  8. Diesel injector dynamic modelling and estimation of injection parameters from impact response part 2: prediction of injection parameters from monitored vibration

    OpenAIRE

    Gu, Fengshou; Ball, Andrew; Rao, K K

    1996-01-01

    Part 2 of this paper presents the experimental and analytical procedures used in the estimation of injection parameters from monitored vibration. The mechanical and flow‐induced sources of vibration in a fuel injector are detailed and the features of the resulting vibration response of the injector body are discussed. Experimental engine test and data acquisition procedures are described, and the use of an out‐of‐the‐engine test facility to confirm injection dependent vibration response is ou...

  9. Strong interaction at finite temperature

    Indian Academy of Sciences (India)

    Abstract. We review two methods discussed in the literature to determine the effective parameters of strongly interacting particles as they move through a heat bath. The first one is the general method of chiral perturbation theory, which may be readily applied to this problem. The other is the method of thermal QCD sum rules ...

  10. Does Vitamin D3 Have an Impact on Clinical and Biochemical Parameters Related to Third Molar Surgery.

    Science.gov (United States)

    Oteri, Giacomo; Cicciù, Marco; Peditto, Matteo; Catalano, Antonino; Loddo, Saverio; Pisano, Michele; Lasco, Antonino

    2016-03-01

    The purpose of this study was to evaluate the clinical effect on the biochemical inflammatory markers of a single oral high dose of cholecalciferol in vitamin D-deficient patients undergoing the surgical removal of lower third molars.A randomized, split-mouth, single-blind study was conducted on 25 vitamin D-deficient patients ranging between 18 and 40 years of age requiring lower third molars extraction and referred at the Oral Surgery Unit of the School of Dentistry of the University of Messina.All patients, with vitamin D3 blood levels ≦30 ng/mL, underwent bilateral surgical removal. The first extraction (control group) being conducted with the administration of a placebo, the second one (test group) being conducted with the preliminary administration of 300,000 IU of cholecalciferol 4 days before the procedure.At each surgery, clinical indexes, such as pain, edema and any functional limitation have been recorded. Clinical and biochemical parameters were registered 4 days before, immediately after, 3 and 7 days after the surgical procedure. The data obtained were processed using paired t-test. The clinical outcome parameters showed a slight to moderate improvement between the control and the vitamin-D treatment group, with statistical significance being obtained regarding the edema at defined time points. Interleukin-1-beta, interleukin-6, and tumor necrosis factor-alpha values were significantly lower (P surgery. The increase of vitamin D serum levels showed an impact on the outcome of the third molar surgery, eliciting a reduced inflammatory response and leading to a more favorable clinical course.

  11. The impact of highway base-saturation flow rate adjustment on Kuwait's transport and environmental parameters estimation.

    Science.gov (United States)

    AlRukaibi, Fahad; AlKheder, Sharaf; Al-Rukaibi, Duaij; Al-Burait, Abdul-Aziz

    2018-03-23

    Traditional transportation systems' management and operation mainly focused on improving traffic mobility and safety without imposing any environmental concerns. Transportation and environmental issues are interrelated and affected by the same parameters especially at signalized intersections. Additionally, traffic congestion at signalized intersections has a major contribution in the environmental problem as related to vehicle emission, fuel consumption, and delay. Therefore, signalized intersections' design and operation is an important parameter to minimize the impact on the environment. The design and operation of signalized intersections are highly dependent on the base saturation flow rate (BSFR). Highway Capacity Manual (HCM) uses a base-saturation flow rate of 1900-passenger car/h/lane for areas with a population intensity greater than or equal to 250,000 and a value of 1750-passenger car/h/lane for less populated areas. The base-saturation flow rate value in HCM is derived from a field data collected in developed countries. The adopted value in Kuwait is 1800passengercar/h/lane, which is the value that used in this analysis as a basis for comparison. Due to the difference in behavior between drivers in developed countries and their fellows in Kuwait, an adjustment was made to the base-saturation flow rate to represent Kuwait's traffic and environmental conditions. The reduction in fuel consumption and vehicles' emission after modifying the base-saturation flow rate (BSFR increased by 12.45%) was about 34% on average. Direct field measurements of the saturation flow rate were used while using the air quality mobile lab to calculate emissions' rates. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. The Impacts of Cardiac Rehabilitation Program on Echocardiographic Parameters in Coronary Artery Disease Patients with Left Ventricular Dysfunction

    Directory of Open Access Journals (Sweden)

    Masoumeh Sadeghi

    2013-01-01

    Full Text Available Introduction. The accurate impact of exercise on coronary artery disease (CAD patients with left ventricular dysfunction is still debatable. We studied the effects of cardiac rehabilitation (CR on echocardiography parameters in CAD patients with ventricular dysfunction. Methods. Patients with CAD who had ventricular dysfunction were included into an exercise-based rehabilitation program and received rehabilitation for eight weeks. All subjects underwent echocardiography before and at the end of the rehabilitation program. The echocardiography parameters, including left ventricular ejection fraction (LVEF, LV end-diastolic (LVEDD and end-systolic diameters (LVESD, and peak exercise capacity measured in metabolic equivalents (METs, were assessed. Results. Seventy patients (mean age = 57.5 ± 10.2 years, 77.1% males were included into the study. At the end of rehabilitation period, the LVEF increased from 45.14 ± 5.77% to 50.44 ± 8.70% (P<0.001, and the peak exercise capacity increased from 8.00 ± 2.56 to 10.08 ± 3.00 METs (P<0.001. There was no significant change in LVEDD (54.63 ± 12.96 to 53.86 ± 8.95 mm, P=0.529 or in LVESD (38.91 ± 10.83 to 38.09 ± 9.04 mm, P=0.378 after rehabilitation. Conclusion. Exercise training in postmyocardial infarction patients with ventricular dysfunction could have beneficial effects on cardiac function without adversely affecting LV remodeling or causing serious cardiac complications.

  13. Studies of the Impact of Magnetic Field Uncertainties on Physics Parameters of the Mu2e Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Bradascio, Federica [Pisa U.

    2016-01-01

    The Mu2e experiment at Fermilab will search for a signature of charged lepton flavor violation, an effect prohibitively too small to be observed within the Standard Model of particle physics. Therefore, its observation is a signal of new physics. The signature that Mu2e will search for is the ratio of the rate of neutrinoless coherent conversion of muons into electrons in the field of a nucleus, relative to the muon capture rate by the nucleus. The conversion process is an example of charged lepton flavor violation. This experiment aims at a sensitivity of four orders of magnitude higher than previous related experiments. The desired sensitivity implies highly demanding requirements of accuracy in the design and conduct of the experiment. It is therefore important to investigate the tolerance of the experiment to instrumental uncertainties and provide specifications that the design and construction must meet. This is the core of the work reported in this thesis. The design of the experiment is based on three superconducting solenoid magnets. The most important uncertainties in the magnetic field of the solenoids can arise from misalignments of the Transport Solenoid, which transfers the beam from the muon production area to the detector area and eliminates beam-originating backgrounds. In this thesis, the field uncertainties induced by possible misalignments and their impact on the physics parameters of the experiment are examined. The physics parameters include the muon and pion stopping rates and the scattering of beam electrons off the capture target, which determine the signal, intrinsic background and late-arriving background yields, respectively. Additionally, a possible test of the Transport Solenoid alignment with low momentum electrons is examined, as an alternative option to measure its field with conventional probes, which is technically difficult due to mechanical interference. Misalignments of the Transport Solenoid were simulated using standard

  14. Impact of line parameter database, continuum absorption, full grind configuration, and L1B update on GOSAT TIR methane retrieval

    Science.gov (United States)

    Yamada, A.; Saitoh, N.; Nonogaki, R.; Imasu, R.; Shiomi, K.; Kuze, A.

    2016-12-01

    The thermal infrared (TIR) band of Thermal and Near-infrared Sensor for Carbon Observation Fourier Transform Spectrometer (TANSO-FTS) onboard Greenhouse Gases Observing Satellite (GOSAT) observes CH4 profile at wavenumber range from 1210 cm-1 to 1360 cm-1 including CH4 ν4 band. The current retrieval algorithm (V1.0) uses LBLRTM V12.1 with AER V3.1 line database to calculate optical depth. LBLRTM V12.1 include MT_CKD 2.5.2 model to calculate continuum absorption. The continuum absorption has large uncertainty, especially temperature dependent coefficient, between BPS model and MT_CKD model in the wavenumber region of 1210-1250 cm-1(Paynter and Ramaswamy, 2014). The purpose of this study is to assess the impact on CH4 retrieval from the line parameter databases and the uncertainty of continuum absorption. We used AER v1.0 database, HITRAN2004 database, HITRAN2008 database, AER V3.2 database, and HITRAN2012 database (Rothman et al. 2005, 2009, and 2013. Clough et al., 2005). AER V1.0 database is based on HITRAN2000. The CH4 line parameters of AER V3.1 and V3.2 databases are developed from HITRAN2008 including updates until May 2009 with line mixing parameters. We compared the retrieved CH4 with the HIPPO CH4 observation (Wofsy et al., 2012). The difference of AER V3.2 was the smallest and 24.1 ± 45.9 ppbv. The differences of AER V1.0, HITRAN2004, HITRAN2008, and HITRAN2012 were 35.6 ± 46.5 ppbv, 37.6 ± 46.3 ppbv, 32.1 ± 46.1 ppbv, and 35.2 ± 46.0 ppbv, respectively. Compare AER V3.2 case to HITRAN2008 case, the line coupling effect reduced difference by 8.0 ppbv. Median values of Residual difference from HITRAN2008 to AER V1.0, HITRAN2004, AER V3.2, and HITRAN2012 were 0.6 K, 0.1 K, -0.08 K, and 0.08 K, respectively, while median values of transmittance difference were less than 0.0003 and transmittance differences have small wavenumber dependence. We also discuss the retrieval error from the uncertainty of the continuum absorption, the test of full grid

  15. Impact of malaria on hematological parameters in people living with HIV/AIDS attending the Laquintinie Hospital in Douala, Cameroon.

    Directory of Open Access Journals (Sweden)

    Gervais Gouana Tchinda

    Full Text Available BACKGROUND: People living with HIV/AIDS (PLWHA frequently have abnormal blood counts including anemia, leucopenia and thrombocytopenia. The role of infection with plasmodia on these hematological parameters in PLWHA is not well known. In this study we compared selected hematological parameters between malaria positive and negative PLWHA. METHODS: We conducted a cross-sectional study of PLWHA attending the Douala Laquintinie hospital. After obtaining consent, demographic and clinical data were obtained via a standardized questionnaire. Blood samples collected for hematological assays were run using an automated full blood counter. Malaria parasitaemia was determined by blood smear microscopy. RESULTS: A total of 238 adult PLWHA were enrolled, 48.3% of who were on antiretroviral therapy and 24.8% of whom had malaria parasitaemia. The respective mean (±SD of hemoglobin level, RBC count, WBC count, platelet count, lymphocyte count and CD4+ T cell counts in malaria co-infected patients versus non-infected patients were: 10.8(±1.9 g/dl versus 11.4(±2.0 g/dl; 3,745,254(±793,353 cells/µl versus 3,888,966(±648,195 cells/µl; 4,403(±1,534 cells/µl versus 4,920(±1,922 cells/µl; 216,051(±93,884 cells/µl versus 226,792(±98,664 cells/µl; 1,846(±711 cells/µl versus 2,052(±845 cells/µl and 245(±195 cells/µl versus 301(±211 cells/µl. All these means were not statistically significantly different from each other. CONCLUSION: There was no significant difference in studied hematological parameters between malaria positive and negative PLWHA. These data suggest little or no impact of malaria infection. Hematological anomalies in PLWHA in this area need not be necessarily attributed to malaria. These need to be further investigated to identify and treat other potential causes.

  16. The Potential Impact of Satellite-Retrieved Cloud Parameters on Ground-Level PM2.5 Mass and Composition

    Science.gov (United States)

    Belle, Jessica H.; Chang, Howard H.; Wang, Yujie; Hu, Xuefei; Lyapustin, Alexei; Liu, Yang

    2017-01-01

    Satellite-retrieved aerosol optical properties have been extensively used to estimate ground-level fine particulate matter (PM2.5) concentrations in support of air pollution health effects research and air quality assessment at the urban to global scales. However, a large proportion, approximately 70%, of satellite observations of aerosols are missing as a result of cloud-cover, surface brightness, and snow-cover. The resulting PM2.5 estimates could therefore be biased due to this non-random data missingness. Cloud-cover in particular has the potential to impact ground-level PM2.5 concentrations through complex chemical and physical processes. We developed a series of statistical models using the Multi-Angle Implementation of Atmospheric Correction (MAIAC) aerosol product at 1 km resolution with information from the MODIS cloud product and meteorological information to investigate the extent to which cloud parameters and associated meteorological conditions impact ground-level aerosols at two urban sites in the US: Atlanta and San Francisco. We find that changes in temperature, wind speed, relative humidity, planetary boundary layer height, convective available potential energy, precipitation, cloud effective radius, cloud optical depth, and cloud emissivity are associated with changes in PM2.5 concentration and composition, and the changes differ by overpass time and cloud phase as well as between the San Francisco and Atlanta sites. A case-study at the San Francisco site confirmed that accounting for cloud-cover and associated meteorological conditions could substantially alter the spatial distribution of monthly ground-level PM2.5 concentrations.

  17. The Potential Impact of Satellite-Retrieved Cloud Parameters on Ground-Level PM2.5Mass and Composition.

    Science.gov (United States)

    Belle, Jessica H; Chang, Howard H; Wang, Yujie; Hu, Xuefei; Lyapustin, Alexei; Liu, Yang

    2017-10-18

    Satellite-retrieved aerosol optical properties have been extensively used to estimate ground-level fine particulate matter (PM 2.5 ) concentrations in support of air pollution health effects research and air quality assessment at the urban to global scales. However, a large proportion, ~70%, of satellite observations of aerosols are missing as a result of cloud-cover, surface brightness, and snow-cover. The resulting PM 2.5 estimates could therefore be biased due to this non-random data missingness. Cloud-cover in particular has the potential to impact ground-level PM 2.5 concentrations through complex chemical and physical processes. We developed a series of statistical models using the Multi-Angle Implementation of Atmospheric Correction (MAIAC) aerosol product at 1 km resolution with information from the MODIS cloud product and meteorological information to investigate the extent to which cloud parameters and associated meteorological conditions impact ground-level aerosols at two urban sites in the US: Atlanta and San Francisco. We find that changes in temperature, wind speed, relative humidity, planetary boundary layer height, convective available potential energy, precipitation, cloud effective radius, cloud optical depth, and cloud emissivity are associated with changes in PM 2.5 concentration and composition, and the changes differ by overpass time and cloud phase as well as between the San Francisco and Atlanta sites. A case-study at the San Francisco site confirmed that accounting for cloud-cover and associated meteorological conditions could substantially alter the spatial distribution of monthly ground-level PM 2.5 concentrations.

  18. The Potential Impact of Satellite-Retrieved Cloud Parameters on Ground-Level PM2.5 Mass and Composition

    Directory of Open Access Journals (Sweden)

    Jessica H. Belle

    2017-10-01

    Full Text Available Satellite-retrieved aerosol optical properties have been extensively used to estimate ground-level fine particulate matter (PM2.5 concentrations in support of air pollution health effects research and air quality assessment at the urban to global scales. However, a large proportion, ~70%, of satellite observations of aerosols are missing as a result of cloud-cover, surface brightness, and snow-cover. The resulting PM2.5 estimates could therefore be biased due to this non-random data missingness. Cloud-cover in particular has the potential to impact ground-level PM2.5 concentrations through complex chemical and physical processes. We developed a series of statistical models using the Multi-Angle Implementation of Atmospheric Correction (MAIAC aerosol product at 1 km resolution with information from the MODIS cloud product and meteorological information to investigate the extent to which cloud parameters and associated meteorological conditions impact ground-level aerosols at two urban sites in the US: Atlanta and San Francisco. We find that changes in temperature, wind speed, relative humidity, planetary boundary layer height, convective available potential energy, precipitation, cloud effective radius, cloud optical depth, and cloud emissivity are associated with changes in PM2.5 concentration and composition, and the changes differ by overpass time and cloud phase as well as between the San Francisco and Atlanta sites. A case-study at the San Francisco site confirmed that accounting for cloud-cover and associated meteorological conditions could substantially alter the spatial distribution of monthly ground-level PM2.5 concentrations.

  19. PYFLOW_2.0: a computer program for calculating flow properties and impact parameters of past dilute pyroclastic density currents based on field data

    Science.gov (United States)

    Dioguardi, Fabio; Mele, Daniela

    2018-03-01

    This paper presents PYFLOW_2.0, a hazard tool for the calculation of the impact parameters of dilute pyroclastic density currents (DPDCs). DPDCs represent the dilute turbulent type of gravity flows that occur during explosive volcanic eruptions; their hazard is the result of their mobility and the capability to laterally impact buildings and infrastructures and to transport variable amounts of volcanic ash along the path. Starting from data coming from the analysis of deposits formed by DPDCs, PYFLOW_2.0 calculates the flow properties (e.g., velocity, bulk density, thickness) and impact parameters (dynamic pressure, deposition time) at the location of the sampled outcrop. Given the inherent uncertainties related to sampling, laboratory analyses, and modeling assumptions, the program provides ranges of variations and probability density functions of the impact parameters rather than single specific values; from these functions, the user can interrogate the program to obtain the value of the computed impact parameter at any specified exceedance probability. In this paper, the sedimentological models implemented in PYFLOW_2.0 are presented, program functionalities are briefly introduced, and two application examples are discussed so as to show the capabilities of the software in quantifying the impact of the analyzed DPDCs in terms of dynamic pressure, volcanic ash concentration, and residence time in the atmosphere. The software and user's manual are made available as a downloadable electronic supplement.

  20. Effects of environmental parameters on the dual-species biofilms formed by Escherichia coli O157:H7 and Ralstonia insidiosa, a strong biofilm producer isolated from a fresh-cut processing plant

    Science.gov (United States)

    Biofilm forming bacteria resident to food processing facilities are a food safety concern due to the potential of biofilms to harbor foodborne bacterial pathogens. When cultured together, Ralstonia insidiosa, a strong biofilm former frequently isolated from produce processing environments, has been ...

  1. Global tilt and lumbar lordosis index: two parameters correlating with health-related quality of life scores-but how do they truly impact disability?

    Science.gov (United States)

    Boissière, Louis; Takemoto, Mitsuru; Bourghli, Anouar; Vital, Jean-Marc; Pellisé, Ferran; Alanay, Ahmet; Yilgor, Caglar; Acaroglu, Emre; Perez-Grueso, Francisco Javier; Kleinstück, Frank; Obeid, Ibrahim

    2017-04-01

    Many radiological parameters have been reported to correlate with patient's disability including sagittal vertical axis (SVA), pelvic tilt (PT), and pelvic incidence minus lumbar lordosis (PI-LL). European literature reports other parameters such as lumbar lordosis index (LLI) and the global tilt (GT). If most parameters correlate with health-related quality of life scores (HRQLs), their impact on disability remains unclear. This study aimed to validate these parameters by investigating their correlation with HRQLs. It also aimed to evaluate the relationship between each of these sagittal parameters and HRQLs to fully understand the impact in adult spinal deformity management. A retrospective review of a multicenter, prospective database was carried out. The database inclusion criteria were adults (>18 years old) presenting any of the following radiographic parameters: scoliosis (Cobb ≥20°), SVA ≥5 cm, thoracic kyphosis ≥60° or PT ≥25°. All patients with complete data at baseline were included. Health-related quality of life scores, demographic variables (DVs), and radiographic parameters were collected at baseline. Differences in HRQLs among groups of each DV were assessed with analyses of variance. Correlations between radiographic variables and HRQLs were assessed using the Spearman rank correlation. Multivariate linear regression models were fitted for each of the HRQLs (Oswestry Disability Index [ODI], Scoliosis Research Society-22 subtotal score, or physical component summaries) with sagittal parameters and covariants as independent variables. A pindex, past surgery, and surgical or non-surgical candidate were significant predictors of ODI score. The likelihood ratio tests for the addition of the sagittal parameters showed that SVA, GT, T1 sagittal tilt, PI-LL, and LLI were statistically significant predictors for ODI score even adjusted for covariates. The differences of R 2 values from Model 1 were 1.5% at maximum, indicating that the addition

  2. Comparison of Different Measurement Tools and Dimensional Parameters of Pterygium to Investigate its Impact on Refractive Indices and Ocular Aberrations.

    Science.gov (United States)

    Gumus, Koray; Guven, Aysegul; Altinkaynak, Miray; Keskin, Merve

    2018-03-01

    The aim of this study was to compare different measurement tools and parameters, including a new computer-assisted image processing technique for the quantitative analysis of the percentage of pterygium on the corneal surface, horizontal/vertical lengths obtained using slitlamp beam and surgical compass. A total of 21 pterygia of 17 patients were included in the study. The pterygia were measured by three different methods: a slitlamp beam, a surgical compass, and a new computer-assisted image processing method. Refractive indices and higher-order aberrations were analyzed in all cases. The new computer-assisted image processing technique revealed excellent intraclass correlation coefficients for intraobserver and interobserver reliability (0.999 and 0.995, respectively). However, horizontal and vertical lengths revealed more deviation between the measurements obtained with slitlamp beam and surgical compass. Although uncorrected visual acuity did not show any significant correlation between horizontal and vertical lengths of pterygia measured by either slitlamp beam or surgical compass, it was correlated with the digital pterygium ratio (rho, 0.462; P=0.035). All ocular aberration (total, higher-order, coma, trefoil, quatrefoil, spherical, and higher-order astigmatism) Root-mean-square values more strongly correlated with higher percentage values of pterygium that covers the cornea, measured by the new computer-assisted image processing technique. The percentage of pterygium covering the corneal surface seems to be more associated with the pterygium-related visual disturbances than with horizontal and vertical lengths measured by conventional techniques. Moreover, the new computer-assisted image processing technique can accurately and reliably measure the percentage extension of pterygium on cornea.

  3. Impact-parameter dependence of neutral pion production in the [sup 36]Ar on [sup 27]Al collision at 95 MeV/nucleon

    Energy Technology Data Exchange (ETDEWEB)

    Badala, A.; Barbera, R.; Palmeri, A.; Pappalardo, G.S.; Riggi, F.; Russo, A.C.; Russo, G.; Turrisi, R.; Agodi, C.; Alba, R.; Bellia, G.; Coniglione, R.; Del Zoppo, A.; Finocchiaro, P.; Maiolino, C.; Migneco, E.; Piattelli, P.; Sapienza, P.; Peghaire, A. (Instituto Nazionale di Fisica Nuclear, Sezione di Catania, I-95129 Catania (Italy) Dipartimento di Fisica, Universita di Catania, Corso Italia, 57-95129 Catania (Italy) Istituto Nazionale di Fisica Nucleare, Laboratorio Nazionale del Sud, Rome (Italy) Grand Accelerateur National d' Ions Lourds, Caen (France))

    1993-11-01

    Neutral pion production has been studied in the [sup 36]Ar+[sup 27]Al reaction at 95 MeV/nucleon with the aim to get a quantitative estimate of its impact-parameter dependence. A near 4[pi] multidetector has been used to detect both the gamma rays originating from the [pi][sup 0] decay and the associated charged particles. The charged particle multiplicity has been used in the present analysis as a global variable to extract the impact parameter scale. A comparison with a Boltzmann-Nordheim-Vlasov calculation, whcih takes into account the effect of pion reabsorption in the nuclear medium, has been performed.

  4. Impact-parameter dependence of neutral pion production in the 36Ar on 27Al collision at 95 MeV/nucleon

    International Nuclear Information System (INIS)

    Badala, A.; Barbera, R.; Palmeri, A.; Pappalardo, G.S.; Riggi, F.; Russo, A.C.; Russo, G.; Turrisi, R.; Agodi, C.; Alba, R.; Bellia, G.; Coniglione, R.; Del Zoppo, A.; Finocchiaro, P.; Maiolino, C.; Migneco, E.; Piattelli, P.; Sapienza, P.; Peghaire, A.

    1993-01-01

    Neutral pion production has been studied in the 36 Ar+ 27 Al reaction at 95 MeV/nucleon with the aim to get a quantitative estimate of its impact-parameter dependence. A near 4π multidetector has been used to detect both the gamma rays originating from the π 0 decay and the associated charged particles. The charged particle multiplicity has been used in the present analysis as a global variable to extract the impact parameter scale. A comparison with a Boltzmann-Nordheim-Vlasov calculation, whcih takes into account the effect of pion reabsorption in the nuclear medium, has been performed

  5. Impact-parameter dependence of the total probability for electromagnetic electron-positron pair production in relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Hencken, K.; Trautmann, D.; Baur, G.

    1995-01-01

    We calculate the impact-parameter-dependent total probability P total (b) for the electromagnetic production of electron-positron pairs in relativistic heavy-ion collisions in lowest order. We study expecially impact parameters smaller than the Compton wavelength of the electron, where the equivalent-photon approximation cannot be used. Calculations with and without a form factor for the heavy ions are done; the influence is found to be small. The lowest-order results are found to violate unitarity and are used for the calculation of multiple-pair production probabilities with the help of the approximate Poisson distribution already found in earlier publications

  6. Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin-spin interactions

    Czech Academy of Sciences Publication Activity Database

    Vavrinská, A.; Zelinka, J.; Šebera, Jakub; Sychrovský, Vladimír; Fiala, R.; Boelens, R.; Sklenář, V.; Trantírek, L.

    2016-01-01

    Roč. 64, č. 1 (2016), s. 53-62 ISSN 0925-2738 R&D Projects: GA ČR GA13-27676S Grant - others:AV ČR(CZ) M200551205 Institutional support: RVO:61388963 Keywords : NMR * DFT calculations * spin-spin interactions * magnetic field Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 2.410, year: 2016 http://link.springer.com/article/10.1007/s10858-015-0005-x

  7. The Impact of Multi-Sensor Data Assimilation on Plant Parameter Retrieval and Yield Estimation for Sugar Beet

    Science.gov (United States)

    Hodrius, M.; Migdall, S.; Bach, H.; Hank, T.

    2015-04-01

    Yield Maps are a basic information source for site-specific farming. For sugar beet they are not available as in-situ measurements. This gap of information can be filled with Earth Observation (EO) data in combination with a plant growth model (PROMET) to improve farming and harvest management. The estimation of yield based on optical satellite imagery and crop growth modelling is more challenging for sugar beet than for other crop types since the plants' roots are harvested. These are not directly visible from EO. In this study, the impact of multi-sensor data assimilation on the yield estimation for sugar beet is evaluated. Yield and plant growth are modelled with PROMET. This multi-physics, raster-based model calculates photosynthesis and crop growth based on the physiological processes in the plant, including the distribution of biomass into the different plant organs (roots, stem, leaves and fruit) at different phenological stages. The crop variable used in the assimilation is the green (photosynthetically active) leaf area, which is derived as spatially heterogeneous input from optical satellite imagery with the radiative transfer model SLC (Soil-Leaf-Canopy). Leaf area index was retrieved from RapidEye, Landsat 8 OLI and Landsat 7 ETM+ data. It could be shown that the used methods are very suitable to derive plant parameters time-series with different sensors. The LAI retrievals from different sensors are quantitatively compared to each other. Results for sugar beet yield estimation are shown for a test-site in Southern Germany. The validation of the yield estimation for the years 2012 to 2014 shows that the approach reproduced the measured yield on field level with high accuracy. Finally, it is demonstrated through comparison of different spatial resolutions that small-scale in-field variety is modelled with adequate results at 20 m raster size, but the results could be improved by recalculating the assimilation at a finer spatial resolution of 5 m.

  8. Impact of skin capsular distance on the performance of controlled attenuation parameter in patients with chronic liver disease.

    Science.gov (United States)

    Shen, Feng; Zheng, Rui-Dan; Shi, Jun-Ping; Mi, Yu-Qiang; Chen, Guo-Feng; Hu, Xiqi; Liu, Yong-Gang; Wang, Xiao-Ying; Pan, Qin; Chen, Guang-Yu; Chen, Jian-Neng; Xu, Liang; Zhang, Rui-Nan; Xu, Lei-Ming; Fan, Jian-Gao

    2015-11-01

    Controlled attenuation parameter (CAP) is a non-invasive method for evaluating hepatic steatosis. However, larger skin capsular distance (SCD) can affect the accuracy. The aim of this study was to investigate the impact of SCD on the diagnostic performance of CAP and liver stiffness measurement (LSM). Of 101 patients with non-alcoholic fatty liver disease (NAFLD) and 280 patients with chronic hepatitis B (CHB) who underwent liver biopsy were prospectively recruited. CAP, LSM and SCD were performed using FibroScan with M probe. The areas under receiver operating characteristics curves (AUROCs) were calculated to determine the diagnostic efficacy. The optimal thresholds were defined by the maximum Youden index. SCD (B 30.34, P multivariate analysis. The AUROCs were slightly higher for SCD 33% (0.90 vs. 0.85) and >66% (0.84 vs. 0.72). For SCD 33% and >66% were 255.0 dB/m, 283.5 dB/m and 293.5 dB/m. However, cut-offs were elevated by approximately 60-70 dB/m for SCD ≥25 mm. When stratified by fibrosis grade, LSM was significantly affected by SCD ≥25 mm for advanced fibrosis (≥F3) in NAFLD, but not in CHB. CAP is a promising tool for detecting and quantifying hepatic steatosis. SCD ≥25 mm may cause overestimation of steatosis. Similarly, SCD ≥25 mm affects the detection of advanced fibrosis by LSM in NAFLD patients. © 2015 The Authors. Liver International Published by John Wiley & Sons Ltd.

  9. Topics in the measurement of top quark events with ATLAS. Pixel detector optoelectronics, track impact parameter calibration, acceptance correction methods

    Energy Technology Data Exchange (ETDEWEB)

    Sandvoss, Stephan A.

    2010-07-01

    The LHC and its experiments will open new possibilities to study precisely the properties of known particles such as the top quark and to find particles never observed before. Careful operation, maintenance and tuning of the detectors and their readout systems are mandatory, in order to obtain high statistics data samples and perform precision measurements. The control and the readout of the ATLAS pixel detector is performed through an optical transmission line. The installation and commissioning of the optical cables as well as the steps from the production to the operation of the Back of Crate cards, which are the optical interface on the off-detector side, are presented in this thesis. Tests of the optical cables have been developed and realized. These tests ensure a complete functionality of all optical cables and prove its operation within given limits. Similarly, the full operability of the Back of Crate cards is assured by a precise production, extensive tests and a careful installation. Since spring 2008, the readout of the pixel detector is ready for operation. Data was taken successfully during cosmics runs, and the tuning of detector and readout is ongoing. A method to map MC distributions of track impact parameters on data was developed, implemented and tested by using misaligned MC samples as data. From the experience gained by the Tevatron experiments CDF and D0 Monte Carlo generators were tuned to predict top quark observables at the LHC. A comparison of five common MC generators was done for the total selection efficiencies and for many distributions, for example the transverse momentum and pseudorapidity of the hadronically decaying top quark. Likewise, detector effects on these distributions were studied by using a full detector simulation and event reconstruction. A method was developed, implemented and tested to reweight the MC distributions from one observable, for example the transverse momentum of the hadronically decaying top quark, such

  10. SU-E-T-391: Evaluation of Image Parameters Impact On the CT Calibration Curve for Proton Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Z; Reyhan, M; Huang, Q; Zhang, M; Yue, N; Chen, T [Rutgers University, New Brunswick, NJ (United States)

    2015-06-15

    Purpose: The calibration of the Hounsfield units (HU) to relative proton stopping powers (RSP) is a crucial component in assuring the accurate delivery of proton therapy dose distributions to patients. The purpose of this work is to assess the uncertainty of CT calibration considering the impact of CT slice thickness, position of the plug within the phantom and phantom sizes. Methods: Stoichiometric calibration method was employed to develop the CT calibration curve. Gammex 467 tissue characterization phantom was scanned in Tomotherapy Cheese phantom and Gammex 451 phantom by using a GE CT scanner. Each plug was individually inserted into the same position of inner and outer ring of phantoms at each time, respectively. 1.25 mm and 2.5 mm slice thickness were used. Other parameters were same. Results: HU of selected human tissues were calculated based on fitted coefficient (Kph, Kcoh and KKN), and RSP were calculated according to the Bethe-Bloch equation. The calibration curve was obtained by fitting cheese phantom data with 1.25 mm thickness. There is no significant difference if the slice thickness, phantom size, position of plug changed in soft tissue. For boney structure, RSP increases up to 1% if the phantom size and the position of plug changed but keep the slice thickness the same. However, if the slice thickness varied from the one in the calibration curve, 0.5%–3% deviation would be expected depending on the plug position. The Inner position shows the obvious deviation (averagely about 2.5%). Conclusion: RSP shows a clinical insignificant deviation in soft tissue region. Special attention may be required when using a different slice thickness from the calibration curve for boney structure. It is clinically practical to address 3% deviation due to different thickness in the definition of clinical margins.

  11. Testing strong interaction theories

    International Nuclear Information System (INIS)

    Ellis, J.

    1979-01-01

    The author discusses possible tests of the current theories of the strong interaction, in particular, quantum chromodynamics. High energy e + e - interactions should provide an excellent means of studying the strong force. (W.D.L.)

  12. Measurement of semi-electronic beauty-hadron decays via their impact parameter in pp collisions in ALICE

    Energy Technology Data Exchange (ETDEWEB)

    Heide, Markus Ansgar

    2014-03-19

    The measurement of beauty-hadron decays via the detection of electron tracks that are displaced from the primary vertex can be performed with ALICE, whose capabilities of electron identification and tracking fulfil all requirements for this task. While the large corresponding branching ratios guarantee sufficient yields of beauty-decay electrons at LHC energies, the wide electron impact parameter distribution due to the long lifetime and the decay kinematics of beauty hadrons allows for a separation of electrons from beauty-hadron decays from background electrons on a statistical basis. This thesis presents the analysis of electrons from beauty-hadron decays in protonproton collisions at centre-of-mass energies of 7 TeV and 2.76 TeV. Using the ALICE central-barrel detectors ITS, TPC, and TOF, p{sub T}-differential electron spectra are measured at mid-rapidity (vertical stroke y vertical stroke <0.8) for transverse momenta between 1 and 8 GeV/c. Information from the TPC and TOF signal is combined to select pure electron samples, whose signal-to-background ratio is subsequently enhanced via the requirement of a minimal impact parameter of the tracks towards the primary vertex in the x - y plane. Tracks from photon conversions occurring outside the innermost ITS layer, which have a wide impact parameter distribution, are rejected via the requirement of hits in both SPD layers of the ITS. The remaining hadron contamination in the selected electron track samples is determined on a statistical basis from the distributions of their energy deposition per unit of length in the TPC. A crucial challenge of this analysis is the subtraction of the electron background originating from charm decays, photon conversions, and light-meson decays from the measured inclusive electron spectrum. The corresponding electron yields are determined using spectra from PYTHIA simulations that are reweighted based on previous measurements of charmed hadrons, π{sup 0}, and η. Minor

  13. Climatic belt dynamics on a tropical mountain under strong anthropogenic and zoogenic impact: Mt Tsebet (3946 m a.s.l.) in East Africa

    Science.gov (United States)

    Nyssen, Jan; Frankl, Amaury; Gebrehiwot, Kindeya; Yirga, Gidey; Guyassa, Etafa; de Mûelenaere, Stephanie; Poesen, Jean; Hemp, Andreas; Haile, Mitiku

    2010-05-01

    The links between decreasing size and volume of the glaciers in East Africa's tropical mountains and the position of climatic belts on the one hand and global warming on the other have led to various interpretations on the occurrence of global warming and its magnitude and impacts in this part of the world. Here, we investigate the existence of temperature changes in East Africa and their impacts in high mountain regions by analyzing the position of climatically determined vegetation belts on Mt. Tsebet (12°52'N, 39°30'E, 3946 m a.s.l.) in northern Ethiopia between 1986 and 2010. This 27 km² massif, which was first surveyed and photographed in 1868, was chosen as a study area because, unlike Simien Mountains or Bale Mts. (Ethiopia), the antropogenic and zoogenic impact on the environment has not been reduced through time. By choosing Tsebet, we avoided areas that have become recently protected (such as the above-mentioned national parks); there, trees that newly grow more upslope might be ascribed to the protected status. In protected areas, the position of upper cropland limits may be controlled by regulations that prevent farmers from expanding farmlands upslope, even if climatic and topographic conditions would allow doing so. On Tsebet, where direct human and zoogenic impact exists up to the highest elevations, we will establish the position of two temperature-linked vegetation limits (i.e. Erica arborea and Hordeum vulgare or barley) in 1986, 1994 and 2010, through fieldwork (February 2010) and aerial photo interpretation. Changes in population density in the villages around Mt. Tsebet will be analysed through house counting on aerial photographs. The fieldwork will include a stay in mountain villages, during which interviews will be done on dates and reasons for shifting of the cultivation limit. The results will be analysed through geostatistical methods and will provide a better understanding of the magnitude of air temperature and possibly precipitation

  14. Soil stochastic parameter correlation impact in the piping erosion failure estimation of riverine flood defences, doi:10.1016/j.strusafe.2016.01.004

    NARCIS (Netherlands)

    Aguilar Lopez, Juan Pablo; Warmink, Jord Jurriaan; Schielen, Ralph Mathias Johannes; Hulscher, Suzanne J.M.H.

    2016-01-01

    Piping erosion has been proved to be one of the failure mechanisms that contributes the most to the total probability of failure on the Dutch flood defence systems. The present study aimed to find the impact of correlation and tail dependence between soil parameters present in the Sellmeijer revised

  15. The impact of changes in the rheological parameters of fine-grained hydromixtures on the efficiency of a selected industrial gravitational hydraulic transport system

    Science.gov (United States)

    Popczyk, Marcin

    2017-11-01

    Polish hard coal mines commonly use hydromixtures in their fire prevention practices. The mixtures are usually prepared based on mass-produced power production wastes, namely the ashes resulting from power production [1]. Such hydromixtures are introduced to the caving area which is formed due to the advancement of a longwall. The first part of the article presents theoretical fundamentals of determining the parameters of gravitational hydraulic transport of water and ash hydromixtures used in the mining pipeline systems. Each hydromixture produced based on fine-grained wastes is characterized by specified rheological parameters that have a direct impact on the future flow parameters of a given pipeline system. Additionally, the gravitational character of the hydraulic transport generates certain limitations concerning the so-called correct hydraulic profile of the system in relation to the applied hydromixture characterized by required rheological parameters that should ensure safe flow at a correct efficiency [2]. The paper includes an example of a gravitational hydraulic transport system and an assessment of the correctness of its hydraulic profile as well as the assessment of the impact of rheological parameters of fine-grained hydromixtures (water and ash) produced based on laboratory tests, depending on the specified flow parameters (efficiency) of the hydromixture in the analyzed system.

  16. Solar eclipse of 20 March 2015 and impacts on irradiance, meteorological parameters, and aerosol properties over southern Italy

    Science.gov (United States)

    Romano, S.; Lo Feudo, T.; Calidonna, C. R.; Burlizzi, P.; Perrone, M. R.

    2017-12-01

    The effects of the partial solar eclipse of 20 March 2015 on short-wave (SW) and long-wave (LW) irradiance measurements, meteorological variables, and near surface particle properties have been investigated. Measurements were performed at three southern Italy observatories of the Global Atmospheric Watch - World Meteorological Organization (GAW-WMO): Lecce (LE, 40.3°N, 18.1°E, 30 m a.s.l.), Lamezia Terme (LT, 38.9°N, 16.2°E, 50 m a.s.l.), and Capo Granitola (CG, 37.6°N, 12.7°E, 50 m a.s.l.), to investigate the dependence of the eclipse effects on monitoring site location and meteorology. LE, LT, and CG were affected by a similar maximum obscuration of the solar disk, but meteorological parameters and aerosol optical and microphysical properties varied from site to site on the eclipse's day. The maximum obscuration of the solar disk, which was equal to 43.6, 42.8, and 45.1% at LE, LT, and CG, respectively, was responsible for the decrease of the downward SW irradiance up to 45, 44, and 45% at LE, LT, and CG, respectively. The upward SW irradiance decreased up to 45, 48, and 44% at LE, LT, and CG, respectively. Consequently, the eclipse SW direct radiative forcing (DRF) was equal to - 307, - 278, and - 238 W m- 2 at LE, LT, and CG, respectively, at the maximum obscuration of the solar disk. The downward and upward LW irradiance decrease was quite small (up to 4%) at the three sites. The time evolution of the meteorological parameters and aerosol optical and microphysical properties and their response strength to the solar eclipse impact varied from site to site, mainly because of the local meteorology and geographical location. Nevertheless, the solar eclipse was responsible at the study sites for a temperature decrease within 0.5-0.8 K, a relative humidity increase within 3.5-4.5%, and a wind speed decrease within 0.5-1.0 m s- 1, because of its cooling effect. The solar eclipse was also responsible at all the sites for the increase of near surface particle

  17. The Impact of Item Position Change on Item Parameters and Common Equating Results under the 3PL Model

    Science.gov (United States)

    Meyers, Jason L.; Murphy, Stephen; Goodman, Joshua; Turhan, Ahmet

    2012-01-01

    Operational testing programs employing item response theory (IRT) applications benefit from of the property of item parameter invariance whereby item parameter estimates obtained from one sample can be applied to other samples (when the underlying assumptions are satisfied). In theory, this feature allows for applications such as computer-adaptive…

  18. High night temperature strongly impacts TCA cycle, amino acid and polyamine biosynthetic pathways in rice in a sensitivity-dependent manner.

    Science.gov (United States)

    Glaubitz, Ulrike; Erban, Alexander; Kopka, Joachim; Hincha, Dirk K; Zuther, Ellen

    2015-10-01

    Global climate change combined with asymmetric warming can have detrimental effects on the yield of crop plants such as rice (Oryza sativa L.). Little is known about metabolic responses of rice to high night temperature (HNT) conditions. Twelve cultivars with different HNT sensitivity were used to investigate metabolic changes in the vegetative stage under HNT compared to control conditions. Central metabolism, especially TCA cycle and amino acid biosynthesis, were strongly affected particularly in sensitive cultivars. Levels of several metabolites were correlated with HNT sensitivity. Furthermore, pool sizes of some metabolites negatively correlated with HNT sensitivity under control conditions, indicating metabolic pre-adaptation in tolerant cultivars. The polyamines putrescine, spermidine and spermine showed increased abundance in sensitive cultivars under HNT conditions. Correlations between the content of polyamines and 75 other metabolites indicated metabolic shifts from correlations with sugar-phosphates and 1-kestose under control to correlations with sugars and amino and organic acids under HNT conditions. Increased expression levels of ADC2 and ODC1, genes encoding enzymes catalysing the first committed steps of putrescine biosynthesis, were restricted to sensitive cultivars under HNT. Additionally, transcript levels of eight polyamine biosynthesis genes were correlated with HNT sensitivity. Responses to HNT in the vegetative stage result in distinct differences between differently responding cultivars with a dysregulation of central metabolism and an increase of polyamine biosynthesis restricted to sensitive cultivars under HNT conditions and a pre-adaptation of tolerant cultivars already under control conditions with higher levels of potentially protective compatible solutes. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  19. Impacts of Earth rotation parameters on GNSS ultra-rapid orbit prediction: Derivation and real-time correction

    Science.gov (United States)

    Wang, Qianxin; Hu, Chao; Xu, Tianhe; Chang, Guobin; Hernández Moraleda, Alberto

    2017-12-01

    Analysis centers (ACs) for global navigation satellite systems (GNSSs) cannot accurately obtain real-time Earth rotation parameters (ERPs). Thus, the prediction of ultra-rapid orbits in the international terrestrial reference system (ITRS) has to utilize the predicted ERPs issued by the International Earth Rotation and Reference Systems Service (IERS) or the International GNSS Service (IGS). In this study, the accuracy of ERPs predicted by IERS and IGS is analyzed. The error of the ERPs predicted for one day can reach 0.15 mas and 0.053 ms in polar motion and UT1-UTC direction, respectively. Then, the impact of ERP errors on ultra-rapid orbit prediction by GNSS is studied. The methods for orbit integration and frame transformation in orbit prediction with introduced ERP errors dominate the accuracy of the predicted orbit. Experimental results show that the transformation from the geocentric celestial references system (GCRS) to ITRS exerts the strongest effect on the accuracy of the predicted ultra-rapid orbit. To obtain the most accurate predicted ultra-rapid orbit, a corresponding real-time orbit correction method is developed. First, orbits without ERP-related errors are predicted on the basis of ITRS observed part of ultra-rapid orbit for use as reference. Then, the corresponding predicted orbit is transformed from GCRS to ITRS to adjust for the predicted ERPs. Finally, the corrected ERPs with error slopes are re-introduced to correct the predicted orbit in ITRS. To validate the proposed method, three experimental schemes are designed: function extrapolation, simulation experiments, and experiments with predicted ultra-rapid orbits and international GNSS Monitoring and Assessment System (iGMAS) products. Experimental results show that using the proposed correction method with IERS products considerably improved the accuracy of ultra-rapid orbit prediction (except the geosynchronous BeiDou orbits). The accuracy of orbit prediction is enhanced by at least 50

  20. Analytical solution of strongly nonlinear Duffing oscillators

    OpenAIRE

    El-Naggar, A.M.; Ismail, G.M.

    2016-01-01

    In this paper, a new perturbation technique is employed to solve strongly nonlinear Duffing oscillators, in which a new parameter α=α(ε)α=α(ε) is defined such that the value of α is always small regardless of the magnitude of the original parameter εε. Therefore, the strongly nonlinear Duffing oscillators with large parameter ε are transformed into a small parameter system with respect to αα. Approximate solution obtained by the present method is compared with the solution of energy balance m...

  1. Study of Seminal Fluid Parameters and Fertility of Male Sickle Cell Disease Patients and Potential Impact of Hydroxyurea Treatment.

    Science.gov (United States)

    Sahoo, Lulup Kumar; Kullu, Bipin Kishore; Patel, Siris; Patel, Nayan Kumar; Rout, Pragyan; Purohit, Prasanta; Meher, Satyabrata

    2017-06-01

    Male Sickle cell disease (SCD) patients often have moderate to severe hypogonadism resulting in abnormal seminal fluid parameters due to testicular dysfunction. Hydroxyurea (HU), the only drug found to be effective in preventing morbidity and mortality in sickle cell disease patients has been found to further aggravate the testicular dysfunction. This was a prospective study done at a tertiary care hospital over 26 months between September 2011 to October 2013. 100 male sickle cell disease patients of age group 15 to 45 years were recruited in the study. We evaluated seminal fluid indices in all patients and the effect of hydroxyurea on seminal fluid parameters. Hydroxyurea was given at low dose of 10mg/kg/day orally to patients with frequent vaso-occlusive crisis and frequent need of blood transfusion. Seminal fluid analysis was done according to WHO criteria before starting hydroxyurea and every 3 months after initiation of hydroxyurea. Patients with abnormal seminal parameters before hydroxyurea therapy were not given hydroxyurea therapy. Patients with abnormal sperm parameters were subjected for FNAC of testis. In sickle cell disease patients with hydroxyurea therapy, who developed abnormal seminal fluid parameters, hydroxyurea was stopped for 3 months and seminal fluid parameters were re-evaluated. Patients who had recovery of seminal indices after hydroxyurea cessation were restarted with hydroxyurea therapy at low dose. Among Sickle cell disease patients without hydroxyurea therapy, 18% of patients developed oligospermia and 4% developed azoospermia. Among sickle cell disease patients with hydroxyurea therapy, 20% of patients developed oligospermia and 10% developed azoospermia. Seminal fluid parameters reverted back to normal after stoppage of hydroxyurea for 3 months in 73% of patients. Alteration of sperm parameters is seen in a significant number of sickle cell disease patients. Also, alterations of seminal fluid parameters are exacerbated by hydroxyurea

  2. Impact of the throat sizing on the operating parameters in an experimental fixed bed gasifier: Analysis, evaluation and testing

    OpenAIRE

    MONTUORI, LINA; Vargas Salgado, Carlos Afranio; Alcázar-Ortega, Manuel

    2015-01-01

    The aim of this research is to contribute into the diffusion of biomass power systems by analyzing and testing the throat sizing influence on the operation of a gasification plant coupled with an internal combustion engine. In order to do this, the assessment of the proper operation range for some of the driving process parameters has been carried out. The analysis has been focused on such parameters as pressure drop of the fixed bed reactor, the inlet air flow, the syngas production, electri...

  3. The Impact of Variability of Selected Geological and Mining Parameters on the Value and Risks of Projects in the Hard Coal Mining Industry

    Science.gov (United States)

    Kopacz, Michał

    2017-09-01

    The paper attempts to assess the impact of variability of selected geological (deposit) parameters on the value and risks of projects in the hard coal mining industry. The study was based on simulated discounted cash flow analysis, while the results were verified for three existing bituminous coal seams. The Monte Carlo simulation was based on nonparametric bootstrap method, while correlations between individual deposit parameters were replicated with use of an empirical copula. The calculations take into account the uncertainty towards the parameters of empirical distributions of the deposit variables. The Net Present Value (NPV) and the Internal Rate of Return (IRR) were selected as the main measures of value and risk, respectively. The impact of volatility and correlation of deposit parameters were analyzed in two aspects, by identifying the overall effect of the correlated variability of the parameters and the indywidual impact of the correlation on the NPV and IRR. For this purpose, a differential approach, allowing determining the value of the possible errors in calculation of these measures in numerical terms, has been used. Based on the study it can be concluded that the mean value of the overall effect of the variability does not exceed 11.8% of NPV and 2.4 percentage points of IRR. Neglecting the correlations results in overestimating the NPV and the IRR by up to 4.4%, and 0.4 percentage point respectively. It should be noted, however, that the differences in NPV and IRR values can vary significantly, while their interpretation depends on the likelihood of implementation. Generalizing the obtained results, based on the average values, the maximum value of the risk premium in the given calculation conditions of the "X" deposit, and the correspondingly large datasets (greater than 2500), should not be higher than 2.4 percentage points. The impact of the analyzed geological parameters on the NPV and IRR depends primarily on their co-existence, which can be

  4. Impact of genetic and climatic factors on parameters of breadmaking quality of wheat kernel and flour starch component

    Directory of Open Access Journals (Sweden)

    Živančev Dragan

    2017-01-01

    Full Text Available This study investigates how genetic and climatic factors affect parameters of breadmaking quality of wheat kernel and flour starch component. Nine wheat cultivars with different combinations of HMW-GS were grown in three production years. Various rheological devices such as Falling Number (FN, Farinograph, Amylograph, Mixolab and SDmatic were used for characterization of milled wheat samples. The most results showed that climatic factors affected parameters of breadmaking quality of wheat kernel and flour starch component more than HMW-GS composition. However, some results of the bread making quality parameters that are considered to be very reliable indicators of changes in starch component of wheat in wet years, such as FN and maximum peak of viscosity by Amylograph, were dependent of HMW-GS composition.

  5. Estimating the impact of various pathway parameters on tenderness, flavour and juiciness of pork using Monte Carlo simulation methods.

    Science.gov (United States)

    Channon, H A; Hamilton, A J; D'Souza, D N; Dunshea, F R

    2016-06-01

    Monte Carlo simulation was investigated as a potential methodology to estimate sensory tenderness, flavour and juiciness scores of pork following the implementation of key pathway interventions known to influence eating quality. Correction factors were established using mean data from published studies investigating key production, processing and cooking parameters. Probability distributions of correction factors were developed for single pathway parameters only, due to lack of interaction data. Except for moisture infusion, ageing period, aitchbone hanging and cooking pork to an internal temperature of >74°C, only small shifts in the mean of the probability distributions of correction factors were observed for the majority of pathway parameters investigated in this study. Output distributions of sensory scores, generated from Monte Carlo simulations of input distributions of correction factors and for individual pigs, indicated that this methodology may be useful in estimating both the shift and variability in pork eating traits when different pathway interventions are applied. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Elimination of bus voltage impact on temperature sensitive electrical parameter during turn-on transition for junction temperature estimation of high-power IGBT modules

    DEFF Research Database (Denmark)

    Luo, Haoze; Iannuzzo, Francesco; Blaabjerg, Frede

    2017-01-01

    -sensitive electrical parameters (DTSEP) during turn-on transient is proposed. Two DTSEP, turn-on delay time (tdon) and the maximum increasing rate of collector current dic/dt(max), are combined to eliminate the bus voltage impact. Using the inherent emitter-auxiliary inductor LeE in high-power modules, the temperature......-dependent DTSEPs can be converted into a low-voltage and measurable signal. Finally, experiment results are exhibited to verify the effectiveness of proposed method....

  7. Comparison of clinical parameters and environmental noise levels between regular surgery and piezosurgery for extraction of impacted third molars

    Directory of Open Access Journals (Sweden)

    Hao-Hueng Chang

    2015-10-01

    Conclusion: The piezosurgery device produced noise levels similar to or lower than those of the high-speed drilling device. However, piezosurgery provides advantages of increased patient comfort during extraction of impacted third molars.

  8. Observation of strong azimuthal asymmetry between slow and fast particles from high energy nuclear collisions

    International Nuclear Information System (INIS)

    Gustafsson, H.A.; Gutbrod, H.H.; Kolb, B.; Loehner, H.; Ludewigt, B.; Poskanzer, A.M.; Renner, T.; Riedesel, H.; Ritter, H.G.; Siemiarczuk, T.; Stepaniak, J.; Warwick, A.; Wieman, H.

    1984-10-01

    Evidence is presented for the strong azimuthal asymmetry between slow and fast fragments in nuclear collisions in the energy interval of 0.4 to 1 GeV per nucleon. The asymmetry gets stronger when incident energy and impact parameter decrease. The results on the A dependence of the azimuthal asymmetry are also presented. (orig.)

  9. Strongly Correlated Topological Insulators

    Science.gov (United States)

    2016-02-03

    Strongly Correlated Topological Insulators In the past year, the grant was used for work in the field of topological phases, with emphasis on finding...surface of topological insulators. In the past 3 years, we have started a new direction, that of fractional topological insulators. These are materials...in which a topologically nontrivial quasi-flat band is fractionally filled and then subject to strong interactions. The views, opinions and/or

  10. Strong Cosmic Censorship

    Science.gov (United States)

    Isenberg, James

    2017-01-01

    The Hawking-Penrose theorems tell us that solutions of Einstein's equations are generally singular, in the sense of the incompleteness of causal geodesics (the paths of physical observers). These singularities might be marked by the blowup of curvature and therefore crushing tidal forces, or by the breakdown of physical determinism. Penrose has conjectured (in his `Strong Cosmic Censorship Conjecture`) that it is generically unbounded curvature that causes singularities, rather than causal breakdown. The verification that ``AVTD behavior'' (marked by the domination of time derivatives over space derivatives) is generically present in a family of solutions has proven to be a useful tool for studying model versions of Strong Cosmic Censorship in that family. I discuss some of the history of Strong Cosmic Censorship, and then discuss what is known about AVTD behavior and Strong Cosmic Censorship in families of solutions defined by varying degrees of isometry, and discuss recent results which we believe will extend this knowledge and provide new support for Strong Cosmic Censorship. I also comment on some of the recent work on ``Weak Null Singularities'', and how this relates to Strong Cosmic Censorship.

  11. The Impact of Model Misspecification on Parameter Estimation and Item-Fit Assessment in Log-Linear Diagnostic Classification Models

    Science.gov (United States)

    Kunina-Habenicht, Olga; Rupp, Andre A.; Wilhelm, Oliver

    2012-01-01

    Using a complex simulation study we investigated parameter recovery, classification accuracy, and performance of two item-fit statistics for correct and misspecified diagnostic classification models within a log-linear modeling framework. The basic manipulated test design factors included the number of respondents (1,000 vs. 10,000), attributes (3…

  12. Difference in grading parameters in architectural schools and its impact on the competency rating of future professionals

    Directory of Open Access Journals (Sweden)

    Oluwole A. Alagbe

    2015-09-01

    Full Text Available Architectural education in Nigeria is divided into at wo-tier training system of four and two years for undergraduate and postgraduate study, respectively. After the completion of postgraduate study, a student is deemed competent to take the professional practice examination. Success in this examination qualifies a student to be registered as an architect. The competency rating of future professionals in architectural schools in Nigeria is determined through a jury system of scoring based on predetermined grading parameters. However, the grading parameters adopted by assessing authorities (academic professors and practitioners representing the professional body differ. The difference in the grading parameters employed by the two approved assessing authorities in Nigeria was investigated in this study. Covenant University in Nigeria was used as a case study. The grading parameters and scores for the 2013 academic session were compared to determine similarities and differences, which might have affected the competency rating of students. Descriptive statistics was employed to analyze the data obtained. Results showed a significant difference in scoring by the two authorities. This difference had a significant consequence on the competency rating of students.

  13. Markov chain beam randomization: a study of the impact of PLANCK beam measurement errors on cosmological parameter estimation

    Science.gov (United States)

    Rocha, G.; Pagano, L.; Górski, K. M.; Huffenberger, K. M.; Lawrence, C. R.; Lange, A. E.

    2010-04-01

    We introduce a new method to propagate uncertainties in the beam shapes used to measure the cosmic microwave background to cosmological parameters determined from those measurements. The method, called markov chain beam randomization (MCBR), randomly samples from a set of templates or functions that describe the beam uncertainties. The method is much faster than direct numerical integration over systematic “nuisance” parameters, and is not restricted to simple, idealized cases as is analytic marginalization. It does not assume the data are normally distributed, and does not require Gaussian priors on the specific systematic uncertainties. We show that MCBR properly accounts for and provides the marginalized errors of the parameters. The method can be generalized and used to propagate any systematic uncertainties for which a set of templates is available. We apply the method to the Planck satellite, and consider future experiments. Beam measurement errors should have a small effect on cosmological parameters as long as the beam fitting is performed after removal of 1/f noise.

  14. Impact of the capillary pressure-saturation pore-size distribution parameter on geological carbon sequestration estimates

    Directory of Open Access Journals (Sweden)

    Chu-Lin Cheng

    2017-01-01

    Full Text Available Cost estimates for geologic carbon sequestration (GCS are vital for policy and decision makers evaluating carbon capture and storage strategies. Numerical models are often used in feasibility studies for the different stages of carbon injection and redistribution. Knowledge of the capillary pressure-saturation function for a selected storage rock unit is essential in applications used for simulating multiphase fluid flow and transport. However, the parameters describing these functions (e.g. the van Genuchten m pore size distribution parameter are often not measured or neglected compared to other physical properties such as porosity and intrinsic permeability. In addition, the use of average instead of point estimates of m for numerical simulations of flow and transport can result in significant errors, especially in the case of coarse-grained sediments and fractured rocks. Such erroneous predictions can pose great risks and challenges to decision-making. We present a comparison of numerical simulation results based on average and point estimates of the van Genuchten m parameter for different porous media. Forward numerical simulations using the STOMP code were employed to illustrate the magnitudes of the differences in carbon sequestration predictions resulting from the use of height-averaged instead of point parameters. The model predictions were converted into cost estimates and the results indicate that varying m values in GCS modeling can cause cost differences of up to hundreds of millions dollars.

  15. Strongly nonlinear oscillators analytical solutions

    CERN Document Server

    Cveticanin, Livija

    2014-01-01

    This book provides the presentation of the motion of pure nonlinear oscillatory systems and various solution procedures which give the approximate solutions of the strong nonlinear oscillator equations. The book presents the original author’s method for the analytical solution procedure of the pure nonlinear oscillator system. After an introduction, the physical explanation of the pure nonlinearity and of the pure nonlinear oscillator is given. The analytical solution for free and forced vibrations of the one-degree-of-freedom strong nonlinear system with constant and time variable parameter is considered. Special attention is given to the one and two mass oscillatory systems with two-degrees-of-freedom. The criteria for the deterministic chaos in ideal and non-ideal pure nonlinear oscillators are derived analytically. The method for suppressing chaos is developed. Important problems are discussed in didactic exercises. The book is self-consistent and suitable as a textbook for students and also for profess...

  16. Relationships between microbial communities and environmental parameters at sites impacted by mining of volcanogenic massive sulfide deposits, Prince William Sound, Alaska

    Science.gov (United States)

    Foster, A.L.; Munk, L.; Koski, R.A.; Shanks, Wayne C.; Stillings, L.L.

    2008-01-01

    The relations among geochemical parameters and sediment microbial communities were examined at three shoreline sites in the Prince William Sound, Alaska, which display varying degrees of impact by acid-rock drainage (ARD) associated with historic mining of volcanogenic massive sulfide deposits. Microbial communities were examined using total fatty acid methyl esters (FAMEs), a class of compounds derived from lipids produced by eukaryotes and prokaryotes (bacteria and Archaea); standard extraction techniques detect FAMEs from both living (viable) and dead (non-viable) biomass, but do not detect Archaeal FAMEs. Biomass and diversity (as estimated by FAMEs) varied strongly as a function of position in the tidal zone, not by study site; subtidal muds, Fe oxyhydroxide undergoing biogenic reductive dissolution, and peat-rich intertidal sediment had the highest values. These estimates were lowest in acid-generating, intertidal zone sediment; if valid, the estimates suggest that only one or two bacterial species predominate in these communities, and/or that Archeal species are important members of the microbial community in this sediment. All samples were dominated by bacterial FAMEs (median value >90%). Samples with the highest absolute abundance of eukaryotic FAMEs were biogenic Fe oxyhydroxides from shallow freshwater pools (fungi) and subtidal muds (diatoms). Eukaryotic FAMEs were practically absent from low-pH, sulfide-rich intertidal zone sediments. The relative abundance of general microbial functional groups such as aerobes/anaerobes and gram(+)/gram(-) was not estimated due to severe inconsistency among the results obtained using several metrics reported in the literature. Principal component analyses (PCAs) were performed to investigate the relationship among samples as separate functions of water, sediment, and FAMEs data. PCAs based on water chemistry and FAMEs data resulted in similar relations among samples, whereas the PCA based on sediment chemistry

  17. Impact of Land Surface and Forcing Parameters on the Spin-up Behaviour of Noah Land Surface Model over the Indian Sub-Continent

    Science.gov (United States)

    Bhattacharya, A.; Satyanarayana, A. N. V.; Mandal, M.

    2018-01-01

    In the present study, an attempt is made to understand the influence of land surface parameters (such as soil moisture conditions, soil type and vegetation type) and forcing parameters on the model spin-up behaviour of a land surface model (LSM), namely Noah LSM, over the Indian sub-continent. The work presented here primarily aims to understand the optimum initial conditions to achieve the least spin-up time over the subtropical conditions that exist over the region of interest. The study is presented in three major parts. In the first part, a multivariate statistical analysis, namely principle component analysis is employed to investigate how parameters such as precipitation, air temperature, soil moisture, radiation components as well as various parameters that characterize soil and vegetation types influence the model spin-up. The second part deals with the study of the impact of soil and vegetation parameters in different seasons on the model spin-up behaviour. Finally, the third part looks into the influence of initial soil moisture condition and precipitation forcing on the spin-up behaviour of the model in different seasons to obtain the optimum initial conditions for the minimum spin-up time of the model. From the study, it is seen that the soil and vegetation type, as well as the soil moisture content influence the model spin-up significantly. The present study reports that the experiments initialized just before a continuous rainfall event has the least spin-up unless the initial soil is saturated.

  18. Dehydroepiandrosterone substitution in female adrenal failure: no impact on endothelial function and cardiovascular parameters despite normalization of androgen status

    DEFF Research Database (Denmark)

    Christiansen, Jens Juel; Andersen, Niels Holmark; Sørensen, Keld E

    2007-01-01

    because of skin side effects and anxiety, respectively. All patients had low circulating androgens baseline and normal range androgens during DHEA treatment. We examined patients with noninvasive endothelial cell function, magnetic resonance imaging (MRI)-based cardiac output, echocardiography, ambulatory...... 24-h blood pressure and maximal oxygen consumption. RESULTS: DHEA treatment normalized androgen status to levels seen in healthy women. DHEA and placebo treatment had no effect on echocardiographic parameters of myocardial dimensions or systolic and diastolic function, noninvasive endothelial cell...... in vascular endothelium has been described and in vitro studies have shown involvement of DHEA in NO dependent pathways. AIM: To evaluate effects of DHEA substitution on cardiovascular parameters. DESIGN: Six months randomized, double-blind, placebo-controlled crossover study. Treatment consisted of DHEA 50...

  19. Application of fuzzy – Neuro to model weather parameter variability impacts on electrical load based on long-term forecasting

    Directory of Open Access Journals (Sweden)

    Danladi Ali

    2018-03-01

    Full Text Available Long-term load forecasting provides vital information about future load and it helps the power industries to make decision regarding electrical energy generation and delivery. In this work, fuzzy – neuro model is developed to forecast a year ahead load in relation to weather parameter (temperature and humidity in Mubi, Adamawa State. It is observed that: electrical load increased with increase in temperature and relative humidity does not show notable effect on electrical load. The accuracy of the prediction is obtained at 98.78% with the corresponding mean absolute percentage error (MAPE of 1.22%. This confirms that fuzzy – neuro is a good tool for load forecasting. Keywords: Electrical load, Load forecasting, Fuzzy logic, Back propagation, Neuro-fuzzy, Weather parameter

  20. Impact of the New CLIC Beam Parameters on the Design of the Post-Collision Line and its Exit Window

    CERN Document Server

    Ferrari, A

    2008-01-01

    Following the recent modification of the CLIC beam parameters, we present an updated design of the post-collision line. As a result of the increase of the beamstrahlung photon cone size, the separation of the outgoing beams by the vertical magnetic chicane is more difficult, but still possible. The main changes in the post-collision line design include the implementation of a common dump for the wrong-sign charged particles of the coherent pairs and for the low-energy tails of the disrupted beam, as well as a significant reduction of the overall lattice length (allowing removal of the large refocusing quadrupoles). The thermal and mechanical stresses in the new exit window, 150 m downstream of the interaction point, were computed. We conclude that, despite the recent changes of the CLIC beam parameters and the necessary modifications of the post-collision line and its exit window, their performance is not significantly affected.

  1. Parameters for the Evaluation of the Fate, Transport, and Environmental Impacts of Chemical Agents in Marine Environments

    Science.gov (United States)

    2007-07-01

    included in this review. Ecotoxicological parameters used for assessing potential ecological effects have also been reviewed elsewhere,11 although the...Perspective, in Textbook of Military Medicine : Medical Aspects of Chemical and Biological Warfare, Washington, DC: Office of the Surgeon General, US...the Marine Environment, Nantes, France, 15-19 March 2004. 287 Neff, M. N., Ecotoxicology of arsenic in the marine environment, Environ. Tox. Chem

  2. Comparative Impacts of Scala Vestibuli Versus Scala Tympani Cochlear Implantation on Auditory Performances and Programming Parameters in Partially Ossified Cochleae.

    Science.gov (United States)

    Trudel, Mathieu; Côté, Mathieu; Philippon, Daniel; Simonyan, David; Villemure-Poliquin, Noémie; Bussières, Richard

    2018-04-26

    To compare scala vestibuli versus scala tympani cochlear implantation in terms of postoperative auditory performances and programming parameters in patients with severe scala tympani ossification. Retrospective case-control study. Tertiary referral center. One hundred three pediatric and adult patients who underwent cochlear implant surgery between 2000 and 2016. Three groups were formed: a scala vestibuli group, a scala tympani with ossification group, and a scala tympani without ossification group. Patients were matched based on their age, sex, duration of deafness, and side of implantation (ratio of 1:2:2). Postoperative evaluation of auditory performances and programming parameters following intensive functional rehabilitation program completion. Multimedia adaptive test (MAT), hearing in noise test (HINT SNR +10 dB, HINT SNR +5 dB, and HINT SNR +0 dB), impedances, neural response telemetry thresholds (NRT), neural response imaging thresholds (NRI), comfortable levels (C-levels), and threshold levels (T-levels) were compared between groups. Twenty-one patients underwent scala vestibuli cochlear implantation: 19 adults and two children. Auditory performances were similar between groups, although sentence recognition in a noisy environment was slightly higher in the scala vestibuli group. Impedance values were also higher in the scala vestibuli group, but all other programming parameters were similar between groups. We present the largest series of patients with scala vestibuli cochlear implantation. This approach provides at least comparable auditory performances without having any deleterious effects on programming parameters. This viable and useful insertion route might be the primary surgical alternative when facing partial cochlear ossification.

  3. IMPACT STUDY OF ANISOTROPIC OPTICAL FIBERS WINDING WITH DIFFERENT TENSION VALUE ON THE H-PARAMETER INVARIANCE DEGREE

    Directory of Open Access Journals (Sweden)

    A. B. Mukhtubayev

    2015-09-01

    Full Text Available Subject of Research. We have investigated the effect of anisotropic optical fibers winding with an elliptical sheath subjecting to stress on the H-parameter invariance degree. This type of optical fiber is used in the manufacture of fiber loop in fiber-optic gyroscopes. Method of Research. The method of research is based on the application of Michelson polarization scanning interferometer as a measuring device. Superluminescent diode with a central wavelength of 1575 nm and a half-width of the spectrum equal to 45 nm is used as a radiation source. The studies were carried out with anisotropic optical fiber with 50 m long elliptical sheath subjecting to stress. The fiber was wound with one layer turn to turn on the coil with a diameter of 18 cm, which is used in the design of fiber-optic gyroscope. The tension force of the optical fiber was controlled during winding on a special machine. Main Results. It was found that at the increase of tension force from 0.05 N to 0.8 H the value of H-parameter increases from 7×10-6 1/m up to 178×10-6 1/m, respectively; i.e. the coupling coefficient of orthogonal modes in the test fiber is being increased. Thus, it is necessary to consider the longitudinal tension force of fiber in the design and manufacture of the fiber-optic sensors of high accuracy class: the less the fiber winding power, the higher invariance degree of distributed H-parameter. The longitudinal tension force of anisotropic optical fiber with elliptical sheath subjecting to stress equal to 0.2 N is recommended in the process of designing fiber-optic gyroscopes. Practical Relevance. The proposed method of Michelson scanning interferometer is usable in the production process for quality determination of the optical fiber winding: no local defects, value controlling of fiber H-parameter.

  4. Assessment of the Impact of GNSS Processing Strategies on the Long-Term Parameters of 20 Years IWV Time Series

    Directory of Open Access Journals (Sweden)

    Zofia Baldysz

    2018-03-01

    Full Text Available Advanced processing of collected global navigation satellite systems (GNSS observations allows for the estimation of zenith tropospheric delay (ZTD, which in turn can be converted to the integrated water vapour (IWV. The proper estimation of GNSS IWV can be affected by the adopted GNSS processing strategy. To verify which of its elements cause deterioration and which improve the estimated GNSS IWV, we conducted eight reprocessings of 20 years of GPS observations (01.1996–12.2015. In each of them, we applied a different mapping function, the zenith hydrostatic delay (ZHD a priori value, the cut-off angle, software, and the positioning method. Obtained in such a way, the ZTD time series were converted to the IWV using the meteorological parameters sourced from the ERA-Interim. Then, based on them, the long-term parameters were estimated and compared to those obtained from the IWV derived from the radio sounding (RS observations. In this paper, we analyzed long-term parameters such as IWV mean values, linear trends, and amplitudes of annual and semiannual oscillations. A comparative analysis showed, inter alia, that in terms of the investigation of the IWV linear trend the precise point positioning (PPP method is characterized by higher accuracy than the differential one. It was also found that using the GPT2 model and the higher elevation mask brings benefits to the GNSS IWV linear trend estimation.

  5. Climate change has only a minor impact on nutrient resorption parameters in a high-latitude peatland.

    NARCIS (Netherlands)

    Aerts, R.; Cornelissen, J.H.C.; van Logtestijn, R.S.P; Callaghan, T.V.

    2007-01-01

    Nutrient resorption from senescing plant tissues is an important determinant of the fitness of plant populations in nutrient-poor ecosystems, because it makes plants less dependent on current nutrient uptake. Moreover, it can have significant "afterlife" effects through its impact on litter

  6. Strong Arcwise Connectedness

    OpenAIRE

    Espinoza, Benjamin; Gartside, Paul; Kovan-Bakan, Merve; Mamatelashvili, Ana

    2012-01-01

    A space is `n-strong arc connected' (n-sac) if for any n points in the space there is an arc in the space visiting them in order. A space is omega-strong arc connected (omega-sac) if it is n-sac for all n. We study these properties in finite graphs, regular continua, and rational continua. There are no 4-sac graphs, but there are 3-sac graphs and graphs which are 2-sac but not 3-sac. For every n there is an n-sac regular continuum, but no regular continuum is omega-sac. There is an omega-sac ...

  7. Abortion: Strong's counterexamples fail

    DEFF Research Database (Denmark)

    Di Nucci, Ezio

    2009-01-01

    This paper shows that the counterexamples proposed by Strong in 2008 in the Journal of Medical Ethics to Marquis's argument against abortion fail. Strong's basic idea is that there are cases--for example, terminally ill patients--where killing an adult human being is prima facie seriously morally......'s scenarios have some valuable future or admitted that killing them is not seriously morally wrong. Finally, if "valuable future" is interpreted as referring to objective standards, one ends up with implausible and unpalatable moral claims....

  8. A strong comeback

    International Nuclear Information System (INIS)

    Marier, D.

    1992-01-01

    This article presents the results of a financial rankings survey which show a strong economic activity in the independent energy industry. The topics of the article include advisor turnover, overseas banks, and the increase in public offerings. The article identifies the top project finance investors for new projects and restructurings and rankings for lenders

  9. Impact of cage stocking density on egg laying characteristics and related stress and immunity parameters of Japanese quails in subtropics.

    Science.gov (United States)

    El-Tarabany, M S

    2016-10-01

    The aim of this study was to investigate the effects of different cage stocking densities on egg production parameters, as well as related stress and immunity indices in Japanese quails under subtropical Egyptian conditions. Two hundred and sixteen birds of Japanese quail at 14th week of age were used in this experiment. The birds were divided randomly into three groups: 60, 72 and 84. Each group subdivided into 4 replicates, where the cages' floor spaces were 200 (S1 ), 167 (S2 ) and 143 (S3 ) cm(2) /bird, respectively. Birds housed at 200 cm(2) /bird (S1 ) had superior fertility (fertility % (p = 0.013) and hatchability % (p = 0.041)), egg production (egg weight (p = 0.034) and egg mass (p = 0.001)) and immunity parameters (higher geometric mean of antibody titres against Newcastle disease virus, p = 0.024). Furthermore, they had higher internal egg quality score: albumen height (p = 0.003), yolk height (p = 0.023), yolk index (p = 0.006) and Haugh unit (p = 0.035). Birds housed at 143 cm(2) /bird (S3 ) had the lowest total leucocytic count and lymphocyte % (p = 0.022), but the highest H/L ratio (p = 0.001). Corticosterone concentration was lower in S1 group (p = 0.031) than that in groups housed at higher densities. Japanese quail housed at high densities revealed drop in fertility, hatchability, production and immunity parameters, indicating a detrimental effects on both welfare and economic income. Journal of Animal Physiology and Animal Nutrition © 2015 Blackwell Verlag GmbH.

  10. Atom collisions in a strong electromagnetic field

    International Nuclear Information System (INIS)

    Smirnov, V.S.; Chaplik, A.V.

    1976-01-01

    It is shown that the long-range part of interatomic interaction is considerably altered in a strong electromagnetic field. Instead of the van der Waals law the potential asymptote can best be described by a dipole-dipole R -3 law. Impact broadening and the line shift in a strong nonresonant field are calculated. The possibility of bound states of two atoms being formed in a strong light field is discussed

  11. Impact of tannic acid on blood pressure, oxidative stress and urinary parameters in L-NNA-induced hypertensive rats

    OpenAIRE

    Turgut Coşan, Didem; Saydam, Faruk; Özbayer, Cansu; Doğaner, Fulya; Soyocak, Ahu; Güneş, Hasan Veysi; Değirmenci, İrfan; Kurt, Hülyam; Üstüner, Mehmet Cengiz; Bal, Cengiz

    2013-01-01

    Hypertension is a major health problem with increasing prevalence around the world. Tannic acid is water-soluble polyphenol that is present in tea, green tea, coffee, red wine, nuts, fruits and many plant foods. It has been reported to serve as an antioxidant or a pro-oxidant depending on the type of cells and its concentration. The purpose of our study was to evaluate the effect of tannic acid on systolic blood pressure, oxidative stress and some urinary parameters in the rat model of essent...

  12. The Impact of Endurance Training on Functional Parameters During the Preparation Phase among Cross-Country Skiers

    Directory of Open Access Journals (Sweden)

    Žiška Peter

    2016-05-01

    Full Text Available In the study, we have tried to demonstrate the effect of endurance training on changes in functional parameters during the preparation phase (12-week mesocycle among cross-country skiers. The group consisted of 10 male cross-country skiers (age: 21.4 ±5 year who completed control (1st 6 week mesocycle and experimental period (2nd 6 week mesocycle.We focused on the following time-varying parameters: changes in maximal oxygen uptake (VO2max, the level of aerobic (AeT and anaerobic thresholds (AT, maximum heart rate (HRmax and performance on the running treadmill. The intra-individual monitoring of each athlete revealed statistical significance of VO2max (mid_VO2max = 69.48 ± 5.72 l.kg-1.min-1, post_ VO2max = 70.96 ± 5.67 ml.kg-1.min-1; p≤0.05 and the level of AT (mid_AT = 86.2 ± 5.43 %, post_AT = 87.8 ± 5.59 %; p≤0.01 the performance on the running treadmill (mid_t = 14:54 ± 1:43 min., post_t = 15:30 ± 1:50 min.; p≤0.05.The significant changes were recorded in the AeT(pre_AeT = 70.3 ± 7.56 %, mid_AeT = 72.5 ± 7.59 %; p≤0.05 in theHRmax(pre_HRmax = 190 ± 8.04 bpm, mid_HRmax = 189 bpm, post_HRmax = 188 ± 7.34 bpm; p = n.s. during control period. We assume that the significant differences occurred as a result of adaptation changes due to training stimuli, which were induced by changes in functional parameters. Increased training volume in zone lower level of oxygen regime (A1, upper level of oxygen regime (A2 and upper level of lactate tolerance(T2 during experimental period elicited changes which reflected the increase functional parameters and performance on the running treadmill compared to that of control period.

  13. Impact of localized gas injection on ICRF coupling and SOL parameters in JET-ILW H-mode plasmas

    Czech Academy of Sciences Publication Activity Database

    Lerche, E.; Goniche, M.; Jacquet, P.; Van Eester, D.; Bobkov, V.; Colas, L.; Czarnecka, A.; Brezinsek, S.; Brix, M.; Crombe, K.; Graham, M.; Groth, M.; Monakhov, I.; Mathurin, T.; Matthews, G.; Meneses, L.; Noble, C.; Petržílka, Václav; Rimini, F.; Shaw, A.

    2015-01-01

    Roč. 463, August (2015), s. 634-639 ISSN 0022-3115. [PLASMA-SURFACE INTERACTIONS 21: International Conference on Plasma-Surface Interactions in Controlled Fusion Devices. Kanazawa, 26.05.2014-30.05.2014] Institutional support: RVO:61389021 Keywords : Ion cyclotron * gas injection Subject RIV: JF - Nuclear Energetics OBOR OECD: Nuclear related engineering Impact factor: 2.199, year: 2015 http://dx.doi.org/10.1016/j.jnucmat.2014.10.074

  14. Impact of basalt based thread linings on the tribological parameters of the clutch linings for motor vehicles

    OpenAIRE

    Danev, Darko; Simeonov, Simeon; Jordanovska, Vase

    2016-01-01

    Friction clutches are still the most widely used type of coupling especially in passenger vehicles. Structural construction of friction clutches is not changed significantly, but their performance is what is constantly being improved. Among other factors that determine the life of the friction clutch i.e. of the friction disk is the quality and friction characteristics of linings. This paper presents the results of experimental research of the impact of the material composition of the linings...

  15. Systematic Review of Ultrasonic Impact Treatment Parameters on Residual Stresses of Welded Non-Sensitized Versus Sensitized Aluminum-Magnesium

    Science.gov (United States)

    2015-03-01

    cycles of wet and dry exposure in this environment, in which concentrated amounts of chloride (dried seawater ) are in contact with the aluminum...around welds in AA5083 installed on-board a U.S. naval combatant and in AA5083 after in situ smface preparat ion . In the AA5456, we examined the...17 1. Systematically Ultrasonic Impact Treated, Gas Metal Arc Welded, Aluminum-Alloy 5456 Plates

  16. Analysis of the impact of sustainability related design parameters in the architectural design process: A case study research

    OpenAIRE

    WEYTJENS, Lieve; VERBEECK, Griet

    2009-01-01

    Literature review shows that early decisions in the architectural design process have the largest impact on the sustainability of the final design. However, in practice, many early decisions on sustainability are solely based on the experience and intuition of the designer. Especially in small projects, which lack engineering support due to limited budgets, designers often only use their own experience to incorporate sustainability in their design. Therefore, a research project has been estab...

  17. Evaluating the impact of extraction and cleanup parameters on the yield of total petroleum hydrocarbons in soil

    Energy Technology Data Exchange (ETDEWEB)

    Saari, Eija; Peraemaeki, Paavo; Jalonen, Jorma [University of Oulu, Department of Chemistry (Finland)

    2008-11-15

    Interlaboratory comparisons for the analysis of mineral oil in polluted soil using the GC-FID method indicate that extraction and cleanup conditions have significant effects on the analytical results. In this investigation a ruggedness test was performed on the extraction and cleanup method for the determination of total petroleum hydrocarbons in soil. A two-level Plackett-Burman design was utilized to study the effect of 11 different method parameters on the extraction recovery of total petroleum hydrocarbons (TPH) in soil. Both qualitative and quantitative factors were investigated. The results indicate that total petroleum hydrocarbons can be relatively reliably monitored through strict implementation of the ISO and CEN draft standards. However, variation in certain method parameters readily affects the validity of the results. The most critical factors affecting TPH recovery were the solvent and co-solvent used for extraction, the extraction time, adsorbent and its weight and sample TPH concentration. Because adaptation of the draft standards especially with respect to these factors easily leads to TPH recoveries higher than 200% or lower than 70%, the validity of the adapted method should always be verified. A proper estimate of the expanded uncertainty should also be appended to TPH results, because only then can the reliability of the results be guaranteed and further justification is gained to support the end-use of the data. This also supports the credibility of the analytical services and prevents the data end-users from drawing misleading conclusions concerning the environmental risks and potential remediation requirements. (orig.)

  18. Incineration of animal by-products--The impact of selected parameters on the flux of flue gas enthalpy.

    Science.gov (United States)

    Bujak, Janusz; Sitarz, Piotr

    2016-04-01

    This paper presents model analyses and tests of animal by-product waste thermal treatment plants. A schedule of tests was prepared, and 62,024 cases of system operation were analysed. A map/work field of the tested plant was drawn up on the basis thereof. Calculations were made following an algorithm described by Bujak (2015a) written in the VBA (Visual Basic for Application) language. The tests showed that when incinerating animal waste, the flux of physical enthalpy of the flue gas from the afterburner chamber depends on numerous design and operating parameters. The most important include the following: humidity and flux of the waste, concentration of oxygen in the flue gas in the afterburner chamber and loss of heat flux to the atmosphere through the external surfaces of the plant. Individual design and operating parameters can be selected so that the process of incineration is ensured without additional fuel. The performed analyses were verified against the actual object at the industrial scale using a meat plant that manufactures ham and processes beef, pork and poultry with a capacity of 150 tonnes/day. The production process waste included mainly bones and - in much smaller quantities - meat and bone meal, at 17 tonnes/day. The performed tests and analyses can be used to optimise the operation of the waste thermal treatment plant at the stages of design and operation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Impact of manual lymphatic drainage on hemodynamic parameters in patients with heart failure and lower limb edema.

    Science.gov (United States)

    Leduc, O; Crasset, V; Leleu, C; Baptiste, N; Koziel, A; Delahaie, C; Pastouret, F; Wilputte, F; Leduc, A

    2011-03-01

    Manual lymphatic drainage (MLD), intermittent sequential pneumatic therapy (ISPT), multilayered bandages (MLB), and compression garments are main techniques in conservative treatment of peripheral lymphedema. Since 1990, it has been thought that ISPT applied to both lower limbs simultaneously should not be used for patients with heart failure because right atrial, pulmonary arterial, and pulmonary wedge pressures may increase to a critical point. In 2005, these same results were observed in patients with heart failure wearing MLB. For these reasons, MLB and ISPT have been contraindicated during lymphedema treatment in cardiac patients. The aim of this study was to determine if we may continue the treatment of lower limb lymphedema using MLD in patients with heart failure. We evaluated hemodynamic parameters using echography during MLD in patients with cardiac disease and obtained circumferential measurements of the edematous limb before and after treatment. MLD treatment significantly decreased the limbs as expected. The heart rate also decreased following MLD in contrast with all other hemodynamic parameters which were not affected by MLD. The findings suggest that there is no contraindication to use MLD in patients with heart failure and lower limb edema.

  20. Assessing the impact of a targeted plyometric training on changes in selected kinematic parameters of the swimming start.

    Science.gov (United States)

    Rejman, Marek; Bilewski, Marek; Szczepan, Stefan; Klarowicz, Andrzej; Rudnik, Daria; Maćkała, Krzysztof

    2017-01-01

    The aim of this study was to analyse changes taking place within selected kinematic parameters of the swimming start, after completing a six-week plyometric training, assuming that the take-off power training improves its effectiveness. The experiment included nine male swimmers. In the pre-test the swimmers performed three starts focusing on the best performance. Next, a plyometric training programme, adapted from sprint running, was introduced in order to increase a power of the lower extremities. The programme entailed 75 minute sessions conducted twice a week. Afterwards, a post-test was performed, analogous to the pre-test. Spatio-temporal structure data of the swimming start were gathered from video recordings of the swimmer above and under water. Impulses triggered by the plyometric training contributed to a shorter start time (the main measure of start effectiveness) and glide time as well as increasing average take-off, flight and glide velocities including take-off, entry and glide instantaneous velocities. The glide angle decreased. The changes in selected parameters of the swimming start and its confirmed diagnostic values, showed the areas to be susceptible to plyometric training and suggested that applied plyometric training programme aimed at increasing take-off power enhances the effectiveness of the swimming start.

  1. Human immunology studies using organ donors: Impact of clinical variations on immune parameters in tissues and circulation.

    Science.gov (United States)

    Carpenter, D J; Granot, T; Matsuoka, N; Senda, T; Kumar, B V; Thome, J J C; Gordon, C L; Miron, M; Weiner, J; Connors, T; Lerner, H; Friedman, A; Kato, T; Griesemer, A D; Farber, D L

    2018-01-01

    Organ donors are sources of physiologically healthy organs and tissues for life-saving transplantation, and have been recently used for human immunology studies which are typically confined to the sampling of peripheral blood. Donors comprise a diverse population with different causes of death and clinical outcomes during hospitalization, and the effects of such variations on immune parameters in blood and tissues are not known. We present here a coordinate analysis of innate and adaptive immune components in blood, lymphoid (bone marrow, spleen, lymph nodes), and mucosal (lungs, intestines) sites from a population of brain-dead organ donors (2 months-93 years; n = 291) across eight clinical parameters. Overall, the blood of donors exhibited similar monocyte and lymphocyte content and low serum levels of pro-inflammatory cytokines as healthy controls; however, donor blood had increased neutrophils and serum levels of IL-8, IL-6, and MCP-1 which varied with cause of death. In tissues, the frequency and composition of monocytes, neutrophils, B lymphocytes and T cell subsets in lymphoid or mucosal sites did not vary with clinical state, and was similar in donors independent of the extent of clinical complications. Our results reveal that organ donors maintain tissue homeostasis, and are a valuable resource for fundamental studies in human immunology. © 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.

  2. Cardiac MRI assessment of right ventricular function: impact of right bundle branch block on the evaluation of cardiac performance parameters

    Energy Technology Data Exchange (ETDEWEB)

    Marterer, Robert; Tschauner, Sebastian; Sorantin, Erich [Medical University of Graz, Division of Pediatric Radiology, Department of Radiology, Graz (Austria); Zeng, Hongchun [First Affiliated Hospital of Xinjiang Medical University, Department of Ultrasonography, Urumqi (China); Koestenberger, Martin [Medical University of Graz, Division of Pediatric Cardiology, Department of Pediatrics and Adolescent Medicine, Graz (Austria)

    2015-12-15

    Right ventricular (RV) function represents a prognostic marker in patients with corrected congenital heart disease. In up to 80 % of these patients, right branch bundle block (RBBB) exists and leads to asynchronous ventricular contraction. The aim of this retrospective study was to evaluate the change of RV performance parameters considering delayed RV end-systolic contraction. RV volumes of 33 patients were assessed twice: 1) not taking account of RBBB (group I), and 2) considering RBBB (group II). According to the RV ejection fraction (EF) for both groups, RV function was classified in different categories (>50 % = normal, 40-50 % = mildly-, 30-40 % = moderately-, <30 % = severely-reduced). The mean time difference between maximal systolic contraction of the septum and RV free wall was 90.7 ms ± 42.6. Consequently, RV end-systolic volume was significantly decreased in group II (p < 0.001). Accordingly, RV stroke volume and RV EF were significantly higher in group II (p < 0.001). There was also a significant change in the assessment of RV function (p < 0.02). RBBB induced delayed RV contraction can be detected at CMR. Ignoring the RV physiology in RBBB patients leads to a statistically significant underscoring of RV performance parameters. (orig.)

  3. Analytical solution of strongly nonlinear Duffing oscillators

    Directory of Open Access Journals (Sweden)

    A.M. El-Naggar

    2016-06-01

    Full Text Available In this paper, a new perturbation technique is employed to solve strongly nonlinear Duffing oscillators, in which a new parameter α=α(ε is defined such that the value of α is always small regardless of the magnitude of the original parameter ε. Therefore, the strongly nonlinear Duffing oscillators with large parameter ε are transformed into a small parameter system with respect to α. Approximate solution obtained by the present method is compared with the solution of energy balance method, homotopy perturbation method, global error minimization method and lastly numerical solution. We observe from the results that this method is very simple, easy to apply, and gives a very good accuracy not only for small parameter εbut also for large values of ε.

  4. Strong Electroweak Symmetry Breaking

    CERN Document Server

    Grinstein, Benjamin

    2011-01-01

    Models of spontaneous breaking of electroweak symmetry by a strong interaction do not have fine tuning/hierarchy problem. They are conceptually elegant and use the only mechanism of spontaneous breaking of a gauge symmetry that is known to occur in nature. The simplest model, minimal technicolor with extended technicolor interactions, is appealing because one can calculate by scaling up from QCD. But it is ruled out on many counts: inappropriately low quark and lepton masses (or excessive FCNC), bad electroweak data fits, light scalar and vector states, etc. However, nature may not choose the minimal model and then we are stuck: except possibly through lattice simulations, we are unable to compute and test the models. In the LHC era it therefore makes sense to abandon specific models (of strong EW breaking) and concentrate on generic features that may indicate discovery. The Technicolor Straw Man is not a model but a parametrized search strategy inspired by a remarkable generic feature of walking technicolor,...

  5. Genetic Parameters and the Impact of Off-Types forTheobroma cacaoL. in a Breeding Program in Brazil.

    Science.gov (United States)

    DuVal, Ashley; Gezan, Salvador A; Mustiga, Guiliana; Stack, Conrad; Marelli, Jean-Philippe; Chaparro, José; Livingstone, Donald; Royaert, Stefan; Motamayor, Juan C

    2017-01-01

    Breeding programs of cacao ( Theobroma cacao L.) trees share the many challenges of breeding long-living perennial crops, and genetic progress is further constrained by both the limited understanding of the inheritance of complex traits and the prevalence of technical issues, such as mislabeled individuals (off-types). To better understand the genetic architecture of cacao, in this study, 13 years of phenotypic data collected from four progeny trials in Bahia, Brazil were analyzed jointly in a multisite analysis. Three separate analyses (multisite, single site with and without off-types) were performed to estimate genetic parameters from statistical models fitted on nine important agronomic traits (yield, seed index, pod index, % healthy pods, % pods infected with witches broom, % of pods other loss, vegetative brooms, diameter, and tree height). Genetic parameters were estimated along with variance components and heritabilities from the multisite analysis, and a trial was fingerprinted with low-density SNP markers to determine the impact of off-types on estimations. Heritabilities ranged from 0.37 to 0.64 for yield and its components and from 0.03 to 0.16 for disease resistance traits. A weighted index was used to make selections for clonal evaluation, and breeding values estimated for the parental selection and estimation of genetic gain. The impact of off-types to breeding progress in cacao was assessed for the first time. Even when present at <5% of the total population, off-types altered selections by 48%, and impacted heritability estimations for all nine of the traits analyzed, including a 41% difference in estimated heritability for yield. These results show that in a mixed model analysis, even a low level of pedigree error can significantly alter estimations of genetic parameters and selections in a breeding program.

  6. Plasmons in strong superconductors

    International Nuclear Information System (INIS)

    Baldo, M.; Ducoin, C.

    2011-01-01

    We present a study of the possible plasmon excitations that can occur in systems where strong superconductivity is present. In these systems the plasmon energy is comparable to or smaller than the pairing gap. As a prototype of these systems we consider the proton component of Neutron Star matter just below the crust when electron screening is not taken into account. For the realistic case we consider in detail the different aspects of the elementary excitations when the proton, electron components are considered within the Random-Phase Approximation generalized to the superfluid case, while the influence of the neutron component is considered only at qualitative level. Electron screening plays a major role in modifying the proton spectrum and spectral function. At the same time the electron plasmon is strongly modified and damped by the indirect coupling with the superfluid proton component, even at moderately low values of the gap. The excitation spectrum shows the interplay of the different components and their relevance for each excitation modes. The results are relevant for neutrino physics and thermodynamical processes in neutron stars. If electron screening is neglected, the spectral properties of the proton component show some resemblance with the physical situation in high-T c superconductors, and we briefly discuss similarities and differences in this connection. In a general prospect, the results of the study emphasize the role of Coulomb interaction in strong superconductors.

  7. Dissimilar Impact Welding of 6111-T4, 5052-H32 Aluminum Alloys to 22MnB5, DP980 Steels and the Structure-Property Relationship of a Strongly Bonded Interface

    Science.gov (United States)

    Liu, Bert; Vivek, Anupam; Presley, Michael; Daehn, Glenn S.

    2018-03-01

    The ability to weld high-strength aluminum to high-strength steel is highly desired for vehicle lightweighting but difficult to attain by conventional means. In this work, vaporizing foil actuator welding was used to successfully weld four Al/Fe combinations consisting of high-strength alloys: AA5052-H32, AA6111-T4, DP980, and 22MnB5. Flyer velocities up to 727 m/s were reached using 10 kJ input energy. In lap-shear testing, samples primarily failed in base aluminum near the aluminum's native strength, showing that the welds were stronger than a base metal and that the base metal was not significantly weakened by the welding process. A particularly strong weld area was studied by transmission electron microscopy to shed light on the microstructural features of strong impact welds. It was found to be characterized by a continuously bonded, fully crystalline interface, extremely fine (nanoscale) grains, mesoscopic as well as microscopic wavy features, and lack of large continuous intermetallic compounds.

  8. Impact of a Strong Magnetic Storm and Two X-Ray Flares on the Ionospheric HF Channel in the Summer Solstice of 2015 According to Oblique Sounding in the Eurasian Region

    Science.gov (United States)

    Uryadov, V. P.; Kolchev, A. A.; Vertogradov, G. G.; Vybornov, F. I.; Egoshin, I. A.; Sklyarevsky, M. S.; Shumaev, V. V.; Chernov, A. G.

    2017-10-01

    We present the results of observations of the impact a strong magnetic storm and two X-ray flares in the summer solstice of 2015 on the HF signal characteristics during oblique sounding of the ionosphere in the Eurasian region. It was found that the negative phase of the magnetic storm led to a strong degradation of the ionospheric channel, up to a long blackout on the paths adjacent to the subauroral latitudes. On the midlatitude paths, a decrease in the maximum observable frequency of the F layer reached 50% with respect to the average values for an undisturbed ionosphere. The propagation velocity of the negative phase of a disturbance from the subauroral to the midlatitude ionosphere is determined (it is equal to about 100 m/s). It is shown that during a magnetic storm the least observable frequency and the average signal-to-noise ratio for the propagation mode via the sporadic E s layer correlate well with the auroral AE index. Anomalous signals were detected in the main phase of the magnetic storm on the Cyprus—Rostov-on-Don path when a chirp ionosonde-radio direction finder was operated in the over-the-horizon HF radar mode. On the basis of modeling and comparison with experimental data, it is shown that the anomalous signals are due to scattering of radio waves by small-scale irregularities located in the subauroral ionospheric F region.

  9. Dissimilar Impact Welding of 6111-T4, 5052-H32 Aluminum Alloys to 22MnB5, DP980 Steels and the Structure-Property Relationship of a Strongly Bonded Interface

    Science.gov (United States)

    Liu, Bert; Vivek, Anupam; Presley, Michael; Daehn, Glenn S.

    2018-01-01

    The ability to weld high-strength aluminum to high-strength steel is highly desired for vehicle lightweighting but difficult to attain by conventional means. In this work, vaporizing foil actuator welding was used to successfully weld four Al/Fe combinations consisting of high-strength alloys: AA5052-H32, AA6111-T4, DP980, and 22MnB5. Flyer velocities up to 727 m/s were reached using 10 kJ input energy. In lap-shear testing, samples primarily failed in base aluminum near the aluminum's native strength, showing that the welds were stronger than a base metal and that the base metal was not significantly weakened by the welding process. A particularly strong weld area was studied by transmission electron microscopy to shed light on the microstructural features of strong impact welds. It was found to be characterized by a continuously bonded, fully crystalline interface, extremely fine (nanoscale) grains, mesoscopic as well as microscopic wavy features, and lack of large continuous intermetallic compounds.

  10. The impact of gender and age on the nutritional parameters of alpaca (Vicugna pacos) meat, colour stability and fat traits.

    Science.gov (United States)

    Smith, M A; Bush, R D; van de Ven, R J; Hall, E J S; Greenwood, P L; Hopkins, D L

    2017-01-01

    Meat quality parameters for 50 huacaya alpacas, representing three age groups (18, 24 and 36months) and two genders (females and castrated males) were studied. Prior to chilling, samples of m. longissimus thoracis et lumborum (LL) were taken to determine isocitrate dehydrogenase activity and glycogen concentration, and further meat quality samples were taken after 24h. Alpaca meat has low levels (Colour stability testing indicated alpaca meat was relatively stable during retail display with day of display having no significant effect on lightness (L*), or the 630nm/580nm ratio. These results may relate to the high proportion (76%) of glycolytic and type IIX muscle fibres in LL. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Impact of xanthohumol (a prenylated flavonoid from hops) on DNA stability and other health-related biochemical parameters

    DEFF Research Database (Denmark)

    Ferk, Franziska; Mišík, Miroslav; Nersesyan, Armen

    2016-01-01

    in single cell gel electrophoresis assays in lymphocytes and of several health-related biomarkers. A decrease of oxidatively damaged purines and protection toward reactive oxygen species induced DNA damage was found after the consumption of the beverage; also the excretion of 8-oxo-7,8-dihydro-2......SCOPE: Xanthohumol (XN) is a hop flavonoid found in beers and refreshment drinks. Results of in vitro and animal studies indicate that it causes beneficial health effects due to DNA protective, anti-inflammatory, antioxidant, and phytoestrogenic properties. Aim of the present study was to find out...... if XN causes alterations of health-related parameters in humans. METHODS AND RESULTS: The effects of the flavonoid were investigated in a randomized crossover intervention trial (n = 22) in which the participants consumed a XN drink (12 mg XN/P/day). We monitored alterations of the DNA stability...

  12. Impact of temperature-humidity index on egg-laying characteristics and related stress and immunity parameters of Japanese quails

    Science.gov (United States)

    El-Tarabany, Mahmoud Salah

    2016-07-01

    The aim of this study was to investigate the effect of temperature-humidity index (THI) level on productive parameters, welfare, and immunity in Japanese quails. One hundred and eighty (180) birds of Japanese quail, 14 weeks old, were used. Birds were divided randomly into three equal groups, control (at low THI, less than 70), H1 (at moderate THI, 70-75), and H2 (at high THI, 76-80). Birds in the control group had higher body weight (281.2 g, p = 0.001), egg mass (745 g, p = 0.001), fertility (85.4 %, p = 0.039), hatchability (80.4 %, p = 0.001), and immune response titer to Newcastle disease virus ( p = 0.031), compared with H2 group. Furthermore, the thermoneutral group had higher internal egg quality score [albumen height (5.14 mm, p = 0.001), yolk height (10.88 mm, p = 0.015), yolk index (42.32 %, p = 0.039), and Haugh unit (92.67, p = 0.001)]. Nevertheless, there were no significant differences in fertility percentage, immune response, and corticosterone concentration between control and H1 group. Birds in the H2 group had the lowest total leucocytic count and lymphocyte percentage ( p = 0.001 and 0.020, respectively) but the highest H/L ratio (0.83, p = 0.001). Corticosterone concentration was lower in control and H1 groups (5.49 and 6.41 ng/mL, respectively, p = 0.024) than that in H2 group. Japanese quail exposed to heat stress revealed drop in production and immunological parameters, as well as a detrimental effects on welfare. Thus, practical approaches might be used to reduce the detrimental effects of greater THI level.

  13. Gender-specific impact of personal health parameters on individual brain aging in cognitively unimpaired elderly subjects

    Directory of Open Access Journals (Sweden)

    Katja eFranke

    2014-05-01

    Full Text Available Aging alters brain structure and function. Personal health markers and modifiable lifestyle factors are related to individual brain aging as well as to the risk of developing Alzheimer’s disease (AD. This study uses a novel magnetic resonance imaging (MRI-based biomarker to assess the effects of 17 health markers on individual brain aging in cognitively unimpaired elderly subjects. By employing kernel regression methods, the expression of normal brain-aging patterns forms the basis to estimate the brain age of a given new subject. If the estimated age is higher than the chronological age, a positive brain age gap estimation (BrainAGE score indicates accelerated atrophy and is considered a risk factor for developing AD. Within this cross-sectional, multi-center study 228 cognitively unimpaired elderly subjects (118 males completed an MRI at 1.5T, physiological and blood parameter assessments. The multivariate regression model combining all measured parameters was capable of explaining 39% of BrainAGE variance in males (p < 0.001 and 32% in females (p < 0.01. Furthermore, markers of the metabolic syndrome as well as markers of liver and kidney functions were profoundly related to BrainAGE scores in males (p < 0.05. In females, markers of liver and kidney functions as well as supply of vitamin B12 were significantly related to BrainAGE (p < 0.05. In conclusion, in cognitively unimpaired elderly subjects several clinical markers of poor health were associated with subtle structural changes in the brain that reflect accelerated aging, whereas protective effects on brain aging were observed for markers of good health. Additionally, the relations between individual brain aging and miscellaneous health markers show gender-specific patterns. The BrainAGE approach may thus serve as a clinically relevant biomarker for the detection of subtly abnormal patterns of brain aging probably preceding cognitive decline and development of AD.

  14. Impact of Polysomnographic Parameters on Continuous Positive Airway Pressure in Patient with Obstructive Sleep Apnea in 2012

    Directory of Open Access Journals (Sweden)

    Abolfazl Mozafari

    2014-06-01

    Full Text Available Background & objectives : O bstructive sleep apnea is a preventable and prevalent major health hazard with serious health consequences including excessive daytime sleepiness, cognitive disturbances, depression, cardiovascular diseases and hypertension. Obstructive sleep apnea is a disorder affecting 2 to 4% of the adult population. The continuous positive airway pressur e (CPAP i s the most efficacious therapy and is often the first option for these patients. The pressure titration during laboratory polysomnography is required for treatment by CPAP.   Methods: The patients with obstructive sleep apnea requiring continuous positive airway pressure treatment were selected . CPAP titration was done according to American Academy of Sleep Medicine protocol. Comparison among continuous positive airway pressure with polysomnographic parameters was performed and analyzed with Pearson correlation coefficient. For analysis of qualitative parameters, we used chi-square and then checked with SPSS version 18 software.   Results: From 125 patients with obstructive sleep apnea, there were 112 cases with inclusion criteria. Mean age of participants was 55.07 ± 12, male frequency was 59.2%, apnea hypopnea index was 43.62 and mean continuous positive airway pressure was 12.50 . There was significant relationship among the pressure of continuous positive airway pressure with apnea hypopnea index (P=0.028, arousal index (P=0.011, body mass index (P=0.041 and O2 desaturation index (P=0.022, although age was not significantly related.   Conclusion: In accordance to this data, we found out a prediction equation for optimal CPAP in our patients

  15. Influence of process parameters on torsional strength, impact toughness and hardness of dissimilar AISI 304 and AISI 1021 friction welded steels

    Directory of Open Access Journals (Sweden)

    Amit Handa

    2014-06-01

    Full Text Available In this present study an attempt was made to join austenitic stainless steel (AISI 304 with low alloy steel (AISI 1021 at different rotational speeds and at different axial pressures and then determining the strength of the joint by means of mechanical properties such as torsional strength, impact strength and micro hardness. The experimental results indicate that the rotational speed and the axial pressure have a significant effect on the mechanical properties of the joint and it is possible to improve the quality of the joint by selecting the optimum parameters.

  16. Impact parameter selected nuclear temperatures of hot nuclei from excited state populations for 40Ar+197Au reactions at E/A=25MeV

    International Nuclear Information System (INIS)

    Li Zuyu; He Zhiyong; Duan Limin; Jin Genming; Wu Heyu; Zhang Baoguo; Wen Wanxin; Qi Yujin; Luo Qingzheng; Dai Guangxi; Wang Hongwei

    1997-01-01

    Nuclear temperatures extracted from excited state populations were measured as a function of linear momentum transfer (LMT) for 40 Ar+ 197 Au reactions at 25MeV/nucleon. The emission temperatures increased slightly with increasing linear momentum transfer or decreasing impact parameter. Taking into account the corrections of detection efficiency and sequential feeding from higher-lying states, a temperature of T∼4MeV was deduced for central collisions. For peripheral collisions the extracted temperatures increased with the energy of the particles. (orig.)

  17. Simulation of the Demand Side Management impacts: resolution enhancement of the input parameters at the local scale

    International Nuclear Information System (INIS)

    Imbert, P.

    2011-01-01

    Following the integrated energy planning paradigm in the 90's and the recent renewal of decentralized energy planning interests, Demand Side Management (DSM) actions are expected to take a significant role on energy planning activities in the future. Indeed the DSM actions represent a relevant option to achieve environmental and energy commitments or to alleviate some specific problems of electricity supply. DSM actions at the local scale at least in the French context is observed today. There is a need for appropriate methods and tools to assess the impacts of such MDE programs at local level. The local scale involves taking into account the specificities of the territories (physical, social, geographical, economical, institutional, etc.) The objective of this thesis is to improve the spatial resolution of input variables for the use in DSM action simulation tools. Based on a case study in France (PREMIO project: smart architecture for load management applied to a district) and an existing simulation tool we will study the impacts of this local experience to several municipalities. (author)

  18. On strongly condensing operators

    Czech Academy of Sciences Publication Activity Database

    Erzakova, N.A.; Väth, Martin

    2017-01-01

    Roč. 196, č. 1 (2017), s. 309-323 ISSN 0373-3114 Institutional support: RVO:67985840 Keywords : asymptotic derivative * compactness * Fréchet derivative Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.864, year: 2016 http://link.springer.com/article/10.1007%2Fs10231-016-0573-8

  19. Modeling spatial and seasonal soil moisture in a semi arid hillslope: The impact of integrating soil surface seal parameters

    Science.gov (United States)

    Sela, Shai; Svoray, Tal; Assouline, Shmuel

    2010-05-01

    Modeling hillslope hydrology and the complex and coupled reaction of runoff processes to rainfall, lies in the focus of a growing number of research studies. The ability to characterize and understand the mechanisms underlying the complex hillslope soil moisture patterns, which trigger spatially variable non linear runoff initiation, still remains a current hydrological challenge especially in ungauged catchments. In humid climates, connectivity of transient moisture patches was suggested as a unifying concept for studying thresholds for subsurface flow and redistribution of soil moisture at the hillslope scale. In semiarid areas, however, transient moisture patches control also the differentiation between evaporation and surface runoff and the ability to identify a unifying concept controlling the large variability of soil moisture at the hillslope scale remains an open research gap. At the LTER Lehavim site in the center of Israel (31020' N, 34045' E) a typical hillslope (0.115 km2) was chosen offering different aspects and a classic geomorphologic banding. The annual rainfall is 290 mm, the soils are brown lithosols and arid brown loess and the dominant rock formations are Eocenean limestone and chalk with patches of calcrete. The vegetation is characterised by scattered dwarf shrubs (dominant species Sarcopoterium spinosum) and patches of herbaceous vegetation, mostly annuals, are spread between rocks and dwarf shrubs. An extensive spatial database of soil hydraulic and environmental parameters (e.g. slope, radiation, bulk density) was measured in the field and interpolated to continuous maps using geostatistical techniques and physically based modelling. To explore the effect of soil surface sealing, Mualem and Assouline (1989) equations describing the change in hydraulic parameters resulting from soil seal formation were applied. Two simple indices were developed to describe local evaporation values and contribution of water from rock outcrops to the soil

  20. Survey of shielding calculation parameters in radiotherapy rooms used in the country and its impact in the existing calculation methodologies

    International Nuclear Information System (INIS)

    Japiassu, Fernando Parois

    2013-01-01

    When designing radiotherapy treatment rooms, the dimensions of barriers are established on the basis of American calculation methodologies specifically; NCRP Report N° 49, NCRP Report N° 51, and more recently, NCRP Report N° 151. Such barrier calculations are based on parameters reflecting predictions of treatments to be performed within the room; which, in tum, reftect a specific reality found in a country. There exists, however, a variety of modern radiotherapy techniques, such as Intensity Modulated Radiation Therapy (IMRT); Total Body Irradiation (TBl) and radiosurgery (SRS); where patierits are treated in a much different way than during more conventional treatrnents, which are not taken into account the traditional shielding calculation methodology. This may lead to a faulty design of treattnent rooms. In order to establish a comparison between the methodology used to calculate shielding design and the reality of treatments performed in Brazil, two radiotherapy facilitie were selected, both of them offering traditional and modern treatment techniqued as described above. Data in relation with reatments perfotmed over a period of six (6)months of operations in both institutions were collected. Based on tlis informaton, a new set of realistic parameters required for shielding design was estãblished, whicb in turn allowed for a nwe caculation of barrier thickness for both facilities. The barrier thickness resultaing from this calculation was then compared with the barrier thickness propose as part of the original shielding design, approved by the regulatory authority. First, concerning the public facility, the thickness of all primary barriers proposed in the shielding design was actually larger than the thickness resulting from calculations based on realistic parameters. Second, concerning the private facility, the new data show that the thickness of three out of the four primary barriers described in the project is larger than the thickness oresulting from

  1. EXPERIMENTAL IMPACT ASSESSMENT OF PARAMETERS PERTAINING TO BLANK TWO-DIMENSIONAL CIRCULAR MOTION ON INTENSITY OF ITS CUTTING AND QUALITY OF MACHINED SURFACE

    Directory of Open Access Journals (Sweden)

    M. G. Kiselev

    2014-01-01

    Full Text Available The purpose of the paper is to make an experimental impact assessment of parameters pertaining to blank two-dimensional circular blank motion on intensity of its cutting and quality of the machined surfaces. Experimental data have been obtained that reveal efficiency in application of blank circular motion and improvement of its output cutting indices.A methodology has been developed for execution of comparative experimental investigations on cutting glass, nephrite and jasper specimens as under conventional conditions required for the operation so while transferring induced oscillations to boom suspension assembly that ensure specimen.The proposed methodology makes it possible to assess quantitatively intensity of specimen cutting and quality of its machined surface. The paper has shown that a positive impact of the specimen circular motion on quality improvement of its cross-cut surface is related to peculiar kinematics features pertaining to relative motion of disc side surface with cross-cut portions of the specimen surface. It has been shown that the intensifying impact of the specimen circular motion on the cutting process is primarily related to the changes in dynamic conditions of its interaction with the cutting edge of the disc. In contrast to conventional cutting when the process is going on under static pressure of contacting surfaces there is their periodical impact-frictional interaction due to transfer of circular motion to the specimen along elliptical trajectory. In this case the rate of the positive impact of the specimen circular motion on its cross-cut surface becomes higher while increasing vertical velocity component that concerns its sliding relative to disc side surface that is ensured by increasing oscillation frequency which is transferred to the boom suspension assembly. Moreover, the rate of positive impact of the specimen circulatory motion on the quality of its cross-cut surface becomes higher while increasing

  2. Impact of tissue specific parameters on the predition of the biological effectiveness for treatment planning in ion beam therapy

    Energy Technology Data Exchange (ETDEWEB)

    Gruen, Rebecca Antonia

    2014-06-03

    Treatment planning in ion beam therapy requires a reliable estimation of the relative biological effectiveness (RBE) of the irradiated tissue. For the pilot project at GSI Helmholtzzentrum fuer Schwerionenforschung GmbH and at other European ion beam therapy centers RBE prediction is based on a biophysical model, the Local Effect Model (LEM). The model version in use, LEM I, is optimized to give a reliable estimation of RBE in the target volume for carbon ion irradiation. However, systematic deviations are observed for the entrance channel of carbon ions and in general for lighter ions. Thus, the LEM has been continuously developed to improve accuracy. The recent version LEM IV has proven to better describe in-vitro cell experiments. Thus, for the clinical application of LEM IV it is of interest to analyze potential differences compared to LEM I under treatment-like conditions. The systematic analysis presented in this work is aiming at the comparison of RBE-weighted doses resulting from different approaches and model versions for protons and carbon ions. This will facilitate the assessment of consequences for clinical application and the interpretation of clinical results from different institutions. In the course of this thesis it has been shown that the RBE-weighted doses predicted on the basis of LEM IV for typical situations representing chordoma treatments differ on average by less than 10 % to those based on LEM I and thus also allow a consistent interpretation of the clinical results. At Japanese ion beam therapy centers the RBE is estimated using their clinical experience from neutron therapy in combination with in-vitro measurements for carbon ions (HIMAC approach). The methods presented in this work allow direct comparison of the HIMAC approach and the LEM and thus of the clinical results obtained at Japanese and European ion beam therapy centers. Furthermore, the sensitivity of the RBE on the model parameters was evaluated. Among all parameters the

  3. Impact of tissue specific parameters on the predition of the biological effectiveness for treatment planning in ion beam therapy

    International Nuclear Information System (INIS)

    Gruen, Rebecca Antonia

    2014-01-01

    Treatment planning in ion beam therapy requires a reliable estimation of the relative biological effectiveness (RBE) of the irradiated tissue. For the pilot project at GSI Helmholtzzentrum fuer Schwerionenforschung GmbH and at other European ion beam therapy centers RBE prediction is based on a biophysical model, the Local Effect Model (LEM). The model version in use, LEM I, is optimized to give a reliable estimation of RBE in the target volume for carbon ion irradiation. However, systematic deviations are observed for the entrance channel of carbon ions and in general for lighter ions. Thus, the LEM has been continuously developed to improve accuracy. The recent version LEM IV has proven to better describe in-vitro cell experiments. Thus, for the clinical application of LEM IV it is of interest to analyze potential differences compared to LEM I under treatment-like conditions. The systematic analysis presented in this work is aiming at the comparison of RBE-weighted doses resulting from different approaches and model versions for protons and carbon ions. This will facilitate the assessment of consequences for clinical application and the interpretation of clinical results from different institutions. In the course of this thesis it has been shown that the RBE-weighted doses predicted on the basis of LEM IV for typical situations representing chordoma treatments differ on average by less than 10 % to those based on LEM I and thus also allow a consistent interpretation of the clinical results. At Japanese ion beam therapy centers the RBE is estimated using their clinical experience from neutron therapy in combination with in-vitro measurements for carbon ions (HIMAC approach). The methods presented in this work allow direct comparison of the HIMAC approach and the LEM and thus of the clinical results obtained at Japanese and European ion beam therapy centers. Furthermore, the sensitivity of the RBE on the model parameters was evaluated. Among all parameters the

  4. Impact of implant-abutment connection on osteoimmunological and microbiological parameters in short implants: a randomized controlled clinical trial.

    Science.gov (United States)

    Öztürk, Veli Özgen; Emingil, Gülnur; Bostanci, Nagihan; Belibasakis, Georgios N

    2017-09-01

    The study aimed to determine the levels of soluble receptor activator of nuclear factor-кB ligand (sRANKL) and osteoprotegerin (OPG) as well as their relative calculated ratio in peri-implant crevicular fluid (PICF) obtained around two different types of implant-abutment connection on short implants following a 12-month monitoring period. Moreover, the levels of a number of oral bacterial species were investigated in the corresponding submucosal biofilm samples. Thirty short implants were randomly placed in posterior maxillary edentulous sites using a split-mouth design in 15 periodontally healthy subjects. Tapered interference fit (TIF) and taper-integrated screwed-in (TIS) types of implant-abutment connections were selected for investigation. PICF and submucosal biofilm samples were collected 1 month after surgery and repeated 12 months after prosthetic loading. Clinical parameters, including probing depth, dichotomous presence of bleeding on probing, and plaque index, were recorded and digital periapical radiographs were taken at each time point. sRANKL and OPG levels in PICF were analyzed using an enzyme-linked immunosorbent assay. Total bacterial levels, as well as levels of Fusobacterium nucleatum, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Prevotella intermedia, and Streptococcus oralis, were analyzed in the corresponding submucosal biofilm samples using quantitative real-time polymerase chain reaction. The total amount of sRANKL in TIF implants was 2.64-fold lower than that in TIS implants at baseline (P  0.05). Accordingly, OPG and RANKL/OPG ratio were similar between the groups at each time point (P > 0.05). Microbiological results were similar in both groups at each time point (P > 0.05). The results of this longitudinal study suggested that sRANKL and OPG in PICF, as well as microbiological parameters in submucosal biofilms, were similar between TIF and TIS implants, after a 12-month monitoring period, despite early

  5. PREFACE: Strongly correlated electron systems Strongly correlated electron systems

    Science.gov (United States)

    Saxena, Siddharth S.; Littlewood, P. B.

    2012-07-01

    This special section is dedicated to the Strongly Correlated Electron Systems Conference (SCES) 2011, which was held from 29 August-3 September 2011, in Cambridge, UK. SCES'2011 is dedicated to 100 years of superconductivity and covers a range of topics in the area of strongly correlated systems. The correlated electronic and magnetic materials featured include f-electron based heavy fermion intermetallics and d-electron based transition metal compounds. The selected papers derived from invited presentations seek to deepen our understanding of the rich physical phenomena that arise from correlation effects. The focus is on quantum phase transitions, non-Fermi liquid phenomena, quantum magnetism, unconventional superconductivity and metal-insulator transitions. Both experimental and theoretical work is presented. Based on fundamental advances in the understanding of electronic materials, much of 20th century materials physics was driven by miniaturisation and integration in the electronics industry to the current generation of nanometre scale devices. The achievements of this industry have brought unprecedented advances to society and well-being, and no doubt there is much further to go—note that this progress is founded on investments and studies in the fundamentals of condensed matter physics from more than 50 years ago. Nevertheless, the defining challenges for the 21st century will lie in the discovery in science, and deployment through engineering, of technologies that can deliver the scale needed to have an impact on the sustainability agenda. Thus the big developments in nanotechnology may lie not in the pursuit of yet smaller transistors, but in the design of new structures that can revolutionise the performance of solar cells, batteries, fuel cells, light-weight structural materials, refrigeration, water purification, etc. The science presented in the papers of this special section also highlights the underlying interest in energy-dense materials, which

  6. Strong-coupling approximations

    International Nuclear Information System (INIS)

    Abbott, R.B.

    1984-03-01

    Standard path-integral techniques such as instanton calculations give good answers for weak-coupling problems, but become unreliable for strong-coupling. Here we consider a method of replacing the original potential by a suitably chosen harmonic oscillator potential. Physically this is motivated by the fact that potential barriers below the level of the ground-state energy of a quantum-mechanical system have little effect. Numerically, results are good, both for quantum-mechanical problems and for massive phi 4 field theory in 1 + 1 dimensions. 9 references, 6 figures

  7. Strong interaction and QFD

    International Nuclear Information System (INIS)

    Ebata, T.

    1981-01-01

    With an assumed weak multiplet structure for bosonic hadrons, which is consistent with the ΔI = 1/2 rule, it is shown that the strong interaction effective hamiltonian is compatible with the weak SU(2) x U(1) gauge transformation. Especially the rho-meson transforms as a triplet under SU(2)sub(w), and this is the origin of the rho-photon analogy. It is also shown that the existence of the non-vanishing Cabibbo angle is a necessary condition for the absence of the exotic hadrons. (orig.)

  8. Impact of sodium chloride on wheat flour dough for yeast-leavened products. II. Baking quality parameters and their relationship.

    Science.gov (United States)

    Beck, Margit; Jekle, Mario; Becker, Thomas

    2012-01-30

    The traditional use of sodium chloride (NaCl) fulfills various important rheological, technological and sensory properties in the manufacturing of yeast-leavened products. However, the use of NaCl in food production has been discussed controversially since a high intake of sodium seems to be associated with hypertension. This study investigates the baking quality parameters of wheat breads containing various levels of NaCl (0-40 g NaCl kg(-1) flour). Crumb firmness and rate of bread staling decreased with decreasing NaCl levels. A slight increase in loaf volume was observed based on the increased yeast leavening ability resulting from additional NaCl. Higher crumb retrogradation (measured by differential scanning calorimetry) was observed with low NaCl levels. The retrogradation effect is based on the theory that NaCl probably leads to Na(+) inclusion in starch molecules during storage and thus reduces retrogradation. Further, significant (P⩽0.05) linear relationships (r ≥ 0.829) between Rheofermentometer results, bread volume and crumb firmness were found, suggesting a predictability of bread quality by measurement of gas release. Copyright © 2011 Society of Chemical Industry.

  9. Impact of vitamin D deficiency on clinical parameters in treatment-naïve rheumatoid arthritis patients.

    Science.gov (United States)

    Liu, Yang; Wen, Hongyan

    2018-02-19

    To determine if patients with rheumatoid arthritis (RA) are at risk of vitamin D deficiency and whether the levels of vitamin D are correlated with clinical parameters in RA. A total of 280 treatment-naïve RA patients, and 140 age- and sex-matched healthy volunteers were enrolled. Serum levels of 1,25-dihydroxycholecalciferol (1,25(OH) 2 D 3 ), the active form of vitamin D, were measured by enzyme-linked immunosorbent assay (ELISA). Concentrations of 1,25(OH) 2 D 3 less than 25 ng/mL were defined as insufficient. Linear regression was performed to evaluate correlations as (modifying and) confounding factors were controlled. The levels of serum 1,25(OH) 2 D 3 in RA individuals (12.24 ± 6.68 ng/ml) were significantly lower than in healthy controls (21.08 ± 7.14 ng/ml; p CCP)-positive patients with RA were lower than in the anti-CCP-negative RA patients (10.86 ng/ml versus 15.98 ng/ml; t = -3.08, p CCP antibody in RA patients.

  10. Process parameter impact on properties of sputtered large-area Mo bilayers for CIGS thin film solar cell applications

    Energy Technology Data Exchange (ETDEWEB)

    Badgujar, Amol C.; Dhage, Sanjay R., E-mail: dhage@arci.res.in; Joshi, Shrikant V.

    2015-08-31

    Copper indium gallium selenide (CIGS) has emerged as a promising candidate for thin film solar cells, with efficiencies approaching those of silicon-based solar cells. To achieve optimum performance in CIGS solar cells, uniform, conductive, stress-free, well-adherent, reflective, crystalline molybdenum (Mo) thin films with preferred orientation (110) are desirable as a back contact on large area glass substrates. The present study focuses on cylindrical rotating DC magnetron sputtered bilayer Mo thin films on 300 mm × 300 mm soda lime glass (SLG) substrates. Key sputtering variables, namely power and Ar gas flow rates, were optimized to achieve best structural, electrical and optical properties. The Mo films were comprehensively characterized and found to possess high degree of thickness uniformity over large area. Best crystallinity, reflectance and sheet resistance was obtained at high sputtering powers and low argon gas flow rates, while mechanical properties like adhesion and residual stress were found to be best at low sputtering power and high argon gas flow rate, thereby indicating a need to arrive at a suitable trade-off during processing. - Highlights: • Sputtering of bilayer molybdenum thin films on soda lime glass • Large area deposition using rotating cylindrical direct current magnetron • Trade of sputter process parameters power and pressure • High uniformity of thickness and best electrical properties obtained • Suitable mechanical and optical properties of molybdenum are achieved for CIGS application.

  11. Scatter radiation breast exposure during head CT: impact of scanning conditions and anthropometric parameters on shielded and unshielded breast dose

    International Nuclear Information System (INIS)

    Klasic, B.; Knezevic, Z.; Vekic, B.; Brnic, Z.; Novacic, K.

    2006-01-01

    Constantly increasing clinical requests for CT scanning of the head on our facility continue to raise concern regarding radiation exposure of patients, especially radiosensitive tissues positioned close to the scanning plane. The aim of our prospective study was to estimate scatter radiation doses to the breast from routine head CT scans, both with and without use of lead shielding, and to establish influence of various technical and anthropometric factors on doses using statistical data analysis. In 85 patient referred to head CT for objective medical reasons, one breast was covered with lead apron during CT scanning. Radiation doses were measured at skin of both breasts and over the apron simultaneously, by the use of thermo luminescent dosimeters. The doses showed a mean reduction by 37% due to lead shielding. After we statistically analyzed our data, we observed significant correlation between under-the-shield dose and values of technical parameters. We used multiple linear regression model to describe the relationships of doses to unshielded and shielded breast respectively, with anthropometric and technical factors. Our study proved lead shielding of the breast to be effective, easy to use and leading to a significant reduction in scatter dose. (author)

  12. Scatter radiation breast exposure during head CT: impact of scanning conditions and anthropometric parameters on shielded and unshielded breast dose

    Energy Technology Data Exchange (ETDEWEB)

    Klasic, B. [Hospital for pulmonary diseases, Zagreb (Croatia); Knezevic, Z.; Vekic, B. [Rudjer Boskovic Institute, Zagreb (Croatia); Brnic, Z.; Novacic, K. [Merkur Univ. Hospital, Zagreb (Croatia)

    2006-07-01

    Constantly increasing clinical requests for CT scanning of the head on our facility continue to raise concern regarding radiation exposure of patients, especially radiosensitive tissues positioned close to the scanning plane. The aim of our prospective study was to estimate scatter radiation doses to the breast from routine head CT scans, both with and without use of lead shielding, and to establish influence of various technical and anthropometric factors on doses using statistical data analysis. In 85 patient referred to head CT for objective medical reasons, one breast was covered with lead apron during CT scanning. Radiation doses were measured at skin of both breasts and over the apron simultaneously, by the use of thermo luminescent dosimeters. The doses showed a mean reduction by 37% due to lead shielding. After we statistically analyzed our data, we observed significant correlation between under-the-shield dose and values of technical parameters. We used multiple linear regression model to describe the relationships of doses to unshielded and shielded breast respectively, with anthropometric and technical factors. Our study proved lead shielding of the breast to be effective, easy to use and leading to a significant reduction in scatter dose. (author)

  13. Impact of chronic exposure to the pesticide chlorpyrifos on respiratory parameters and sleep apnea in juvenile and adult rats.

    Directory of Open Access Journals (Sweden)

    Walaa Darwiche

    Full Text Available The widely used organophosphorus pesticide chlorpyrifos (CPF is often detected in food. CPF inhibits acetylcholinesterase and can modify muscle contractility and respiratory patterns. We studied the effects of chronic exposure to CPF on respiratory parameters and diaphragm contractility in 21- and 60-days old rats. Pregnant rats were exposed to oral CPF (1 or 5 mg/ kg /day: CPF-1 or CPF-5 groups vs vehicle: controls from gestation onset up to weaning of the pups that were individually gavaged (CPF or vehicle thereafter. Two developmental time points were studied: weaning (day 21 and adulthood (day 60. Whole-body plethysmography was used to score breathing patterns and apnea index during sleep. Then, diaphragm strips were dissected for the assessment of contractility and acetylcholinesterase activity. Results showed that the sleep apnea index was higher in CPF-exposed rats than in controls. In adult rats, the expiratory time and tidal volume were higher in CPF-exposed animals than in controls. At both ages, the diaphragm's amplitude of contraction and fatigability index were higher in the CPF-5 group, due to lower acetylcholinesterase activity. We conclude that chronic exposure to CPF is associated with higher sleep apnea index and diaphragm contractility, and modifies respiratory patterns in sleeping juvenile and adult rats.

  14. Transportation radiological risk assessment for the programmatic environmental impact statement: An overview of methodologies, assumptions, and input parameters

    International Nuclear Information System (INIS)

    Monette, F.; Biwer, B.; LePoire, D.; Chen, S.Y.

    1994-01-01

    The U.S. Department of Energy is considering a broad range of alternatives for the future configuration of radioactive waste management at its network of facilities. Because the transportation of radioactive waste is an integral component of the management alternatives being considered, the estimated human health risks associated with both routine and accident transportation conditions must be assessed to allow a complete appraisal of the alternatives. This paper provides an overview of the technical approach being used to assess the radiological risks from the transportation of radioactive wastes. The approach presented employs the RADTRAN 4 computer code to estimate the collective population risk during routine and accident transportation conditions. Supplemental analyses are conducted using the RISKIND computer code to address areas of specific concern to individuals or population subgroups. RISKIND is used for estimating routine doses to maximally exposed individuals and for assessing the consequences of the most severe credible transportation accidents. The transportation risk assessment is designed to ensure -- through uniform and judicious selection of models, data, and assumptions -- that relative comparisons of risk among the various alternatives are meaningful. This is accomplished by uniformly applying common input parameters and assumptions to each waste type for all alternatives. The approach presented can be applied to all radioactive waste types and provides a consistent and comprehensive evaluation of transportation-related risk

  15. Strong Coupling Holography

    CERN Document Server

    Dvali, Gia

    2009-01-01

    We show that whenever a 4-dimensional theory with N particle species emerges as a consistent low energy description of a 3-brane embedded in an asymptotically-flat (4+d)-dimensional space, the holographic scale of high-dimensional gravity sets the strong coupling scale of the 4D theory. This connection persists in the limit in which gravity can be consistently decoupled. We demonstrate this effect for orbifold planes, as well as for the solitonic branes and string theoretic D-branes. In all cases the emergence of a 4D strong coupling scale from bulk holography is a persistent phenomenon. The effect turns out to be insensitive even to such extreme deformations of the brane action that seemingly shield 4D theory from the bulk gravity effects. A well understood example of such deformation is given by large 4D Einstein term in the 3-brane action, which is known to suppress the strength of 5D gravity at short distances and change the 5D Newton's law into the four-dimensional one. Nevertheless, we observe that the ...

  16. Perspectives on geochemical proxies: The impact of model and parameter selection on the quantification of carbonate recrystallization rates

    Science.gov (United States)

    Huber, Christian; Druhan, Jennifer L.; Fantle, Matthew S.

    2017-11-01

    Diagenetic reactions in marine sediments, such as the recrystallization of carbonates, can impact the accuracy of paleo-environmental and paleo-climatic reconstructions by geochemical proxies. The extent to which the recrystallization of carbonates affects the chemistry of sedimentary archives depends on the reaction rate, extent of isotopic disequilibrium, and duration of reaction. The reaction rate, which is obviously critical, can be constrained by the elemental and isotopic compositions of pore fluids. Such constraints are affected by assumptions regarding the temperature in the sedimentary column relative to the temperature of formation, the burial rate, pore fluid advection, the composition of the sediments (carbonate-rich versus siliciclastic), and the porosity of the sediment column. In this study, we use a steady-state analytical solution to the diagenetic equations to constrain depth-dependent reaction rates (and extents of recrystallization) based on the Ca isotopic compositions of pore fluids in sedimentary columns at multiple ocean drilling sites (Sites 807, 984, 1170, and 1171), which encompass a diverse range of sedimentary compositions and conditions. We find that carbonates in siliciclastic sediments are generally less altered by diagenesis than their carbonate-rich counterparts. The discrepancy in recrystallization rates between siliciclastic and carbonate-rich sedimentary sections is, however, significantly smaller than previously estimated, suggesting that siliciclastic archives are not immune to diagenetic effects. While we find that diagenesis can decouple contemporaneous proxies of sea surface temperature (Mg/Ca and δ18O), our calculations also reveal that δ18O-based temperature estimates are more robust in siliciclastic sections relative to carbonate-rich sections. Sensitivity tests of the calculated extent of recrystallization suggest that uncertainties in porosity and burial rate are generally the greatest sources of error to proxy

  17. Study of the applicability of Markov chain Monte Carlo methods to the statistical separation of electron sources via the impact parameter for ALICE

    Energy Technology Data Exchange (ETDEWEB)

    Wittner, Manuel [Physikalisches Institut, Universitaet Heidelberg, Heidelberg (Germany); Collaboration: ALICE-Collaboration

    2015-07-01

    One particularly interesting measurement detected by the ALICE set-up at the LHC are electrons from charm and beauty hadron decays. Heavy quarks originate from initial hard scattering processes and thus experience the whole history of a heavy ion collision. Therefore, they are valuable probes to study the mechanisms of energy loss and hadronization in the hot and dense state of matter, that is expected to be formed in a heavy-ion collision at LHC. One important task is the distinction of the different electron sources, for which a method was developed. Hereby, the impact parameter distribution of the measurement data is compared with impact parameter distributions for the individual sources, which are created through Monte Carlo simulations. Afterwards, a maximum likelihood fit is applied. However, creating a posterior distribution of the likelihood according to Bayes' theorem and sampling it with Markov Chain Monte Carlo algorithms provides several advantages, e.g. a mathematically correct estimation of the uncertainties or the usage of prior knowledge. Hence for the first time in this particular problem, a Markov Chain Monte Carlo algorithm, namely the Metropolis algorithm, was implemented and investigated for its applicability in heavy flavor physics. First studies indicate its great usefulness in this field of physics.

  18. Study of an Impact-Parameter Optical Discriminator to be used for Beauty Search in Fixed-Target Mode~ at~the~LHC

    CERN Multimedia

    2002-01-01

    % RD30 \\\\ \\\\ We propose a research and development of an $^{\\prime}$Optical Trigger$^{\\prime}$ to be used for B-meson selection in a LHC fixed-target experiment. The optical trigger relies on the detection of Cerenkov light produced and trapped in a thin spherical crystal viewed by a fast photodetector. The device is, in principle, sensitive to charged particles with large impact parameter arising from secondary vertices belonging to the B-meson chain, but it is blind to minimum bias events originating in a small target. A full prototype using LiF fluoride crystal in 1992 and the experimental results are in agreement with expectations. Backgrounds due to delta-rays and nuclear interactions are measured to be about 2\\%. A second generation prototype with Sapphire crystal and liquid cladding is developed to improve the sensitivity of the device at very low impact parameters (100~$\\mu$m). A third generation prototype with fiber read-out is also under preparation. To improve further the sensitivity a novel read-o...

  19. Impact of seasonal thermal stress on physiological and blood biochemical parameters in pigs under different dietary energy levels.

    Science.gov (United States)

    Pathak, P K; Roychoudhury, R; Saharia, J; Borah, M C; Dutta, D J; Bhuyan, R; Kalita, D

    2018-02-13

    The present study was formulated to find out the status of important season related thermal stress biomarkers of pure-bred (Hampshire) and crossbred (50% Hampshire × 50% local) pigs under the agro-climatic condition of Assam State, India. The experiment was also aimed to study the role of different level of energy ration (110, 100, and 90% energy of NRC feeding standard for pig) in variation of physiological and biochemical parameters in two genetic groups of pigs in different seasons. The metabolizable energy value were 3260, 2936.5, and 3585.8 kcal/kg in grower ration and 3260.2, 2936.6, and 3587 kcal/kg in finisher ration for normal energy (NE), low energy (LE) and high energy (HE), respectively. Both the genetic group of animals were housed separately under intensive system of management. Each pen was measuring 10' × 12' along with an outer enclosure. Six weaned piglets (almost similar body weight of average 10.55 kg) of each group were kept in a separate pen. However, after attainment of 35 kg body weight, the animals of a group were divided in two pens of three animals each. The present experiment indicated that average ambient temperature during summer months (27.33-29.51 °C) was above the comfort zone for pigs (22 °C). The significantly (P energy (HE) ration during summer season. Serum triiodothyronine (T 3 ) and thyroxine (T 4 ) concentrations were significantly (P energy level of the ration might be helpful to minimize the effects of thermal stress during summer.

  20. Testing impact of the strategy of VLBI data analysis on the estimation of Earth Orientation Parameters and station coordinates

    Directory of Open Access Journals (Sweden)

    Wielgosz Agata

    2016-06-01

    Full Text Available Very Long Baseline Interferometry (VLBI is the only space geodetic technique capable to realise the Celestial Reference Frame and tie it with the Terrestrial Reference Frame. It is also the only technique, which measures all the Earth Orientation Parameters (EOP on a regular basis, thus the role of VLBI in determination of the universal time, nutation and polar motion and station coordinates is invaluable. Although geodetic VLBI has been providing observations for more than 30 years, there are no clear guidelines how to deal with the stations or baselines having significantly bigger post-fit residuals than the other ones. In our work we compare the common weighting strategy, using squared formal errors, with strategies involving exclusion or down-weighting of stations or baselines. For that purpose we apply the Vienna VLBI Software VieVS with necessary additional procedures. In our analysis we focus on statistical indicators that might be the criterion of excluding or down-weighting the inferior stations or baselines, as well as on the influence of adopted strategy on the EOP and station coordinates estimation. Our analysis shows that in about 99% of 24-hour VLBI sessions there is no need to exclude any data as the down-weighting procedure is sufficiently efficient. Although results presented here do not clearly indicate the best algorithm, they show strengths and weaknesses of the applied methods and point some limitations of automatic analysis of VLBI data. Moreover, it is also shown that the influence of the adopted weighting strategy is not always clearly reflected in the results of analysis.

  1. Impact of Clinical Parameters in the Intrahost Evolution of HIV-1 Subtype B in Pediatric Patients: A Machine Learning Approach.

    Science.gov (United States)

    Rojas Sánchez, Patricia; Cobos, Alberto; Navaro, Marisa; Ramos, José Tomas; Pagán, Israel; Holguín, África

    2017-10-01

    Determining the factors modulating the genetic diversity of HIV-1 populations is essential to understand viral evolution. This study analyzes the relative importance of clinical factors in the intrahost HIV-1 subtype B (HIV-1B) evolution and in the fixation of drug resistance mutations (DRM) during longitudinal pediatric HIV-1 infection. We recovered 162 partial HIV-1B pol sequences (from 3 to 24 per patient) from 24 perinatally infected patients from the Madrid Cohort of HIV-1 infected children and adolescents in a time interval ranging from 2.2 to 20.3 years. We applied machine learning classification methods to analyze the relative importance of 28 clinical/epidemiological/virological factors in the HIV-1B evolution to predict HIV-1B genetic diversity (d), nonsynonymous and synonymous mutations (dN, dS) and DRM presence. Most of the 24 HIV-1B infected pediatric patients were Spanish (91.7%), diagnosed before 2000 (83.3%), and all were antiretroviral therapy experienced. They had from 0.3 to 18.8 years of HIV-1 exposure at sampling time. Most sequences presented DRM. The best-predictor variables for HIV-1B evolutionary parameters were the age of HIV-1 diagnosis for d, the age at first antiretroviral treatment for dN and the year of HIV-1 diagnosis for ds. The year of infection (birth year) and year of sampling seemed to be relevant for fixation of both DRM at large and, considering drug families, to protease inhibitors (PI). This study identifies, for the first time using machine learning, the factors affecting more HIV-1B pol evolution and those affecting DRM fixation in HIV-1B infected pediatric patients. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  2. Relationships between cardiac innervation/perfusion imbalance and ventricular arrhythmias: impact on invasive electrophysiological parameters and ablation procedures

    Energy Technology Data Exchange (ETDEWEB)

    Gimelli, Alessia [Fondazione Toscana Gabriele Monasterio, Pisa (Italy); Menichetti, Francesca; Soldati, Ezio; Liga, Riccardo; Vannozzi, Andrea; Bongiorni, Maria Grazia [University Hospital of Pisa, Cardio-Thoracic and Vascular Department, Pisa (Italy); Marzullo, Paolo [Fondazione Toscana Gabriele Monasterio, Pisa (Italy); CNR, Institute of Clinical Physiology, Pisa (Italy)

    2016-12-15

    To assess the relationship between regional myocardial perfusion and sympathetic innervation parameters at myocardial scintigraphy and intra-cavitary electrophysiological data in patients with ventricular arrhythmias (VA) submitted to invasive electrophysiological study and ablation procedure. Sixteen subjects underwent invasive electrophysiological study with electroanatomical mapping (EAM) followed by trans-catheter ablations of VA. Before ablation all patients were studied with a combined evaluation of regional myocardial perfusion and sympathetic innervation by means of tomographic {sup 99m}Tc-tetrofosmin and {sup 123}I- metaiodobenzylguanidine cadmium-zinc-telluride (CZT) scintigraphies, respectively. Off-line spatial co-registration of CZT perfusion and innervation data with the three-dimensional EAM reconstruction was performed in every patient. CZT revealed the presence of myocardial scar in 55 (20 %) segments. Of the viable myocardial segments, 131 (60 %) presented a preserved adrenergic innervation, while 86 (40 %) showed a significantly depressed innervation (i.e. innervation/perfusion mismatch). On EAM, the invasively measured intra-cavitary voltage was significantly lower in scarred segments than in viable ones (1.7 ± 1.5 mV vs. 4.0 ± 2.2 mV, P < 0.001). Interestingly, among the viable segments, those showing an innervation/perfusion mismatch presented a significantly lower intra-cavitary voltage than those with preserved innervation (1.9 ± 2.5 mV vs. 4.7 ± 2.3 mV, P < 0.001). Intra-cardiac ablation was performed in 63 (23 %) segments. On multivariate analysis, after correction for scar burden, the segments showing an innervation/perfusion mismatch remained the most frequent ablation targets (OR 5.6, 95 % CI 1.5-20.8; P = 0.009). In patients with VA, intra-cavitary electrical abnormalities frequently originate at the level of viable myocardial segments with depressed sympathetic innervation that frequently represents the ultimate ablation target

  3. The Impact of Ozone Treatment in Dynamic Bed Parameters on Changes in Biologically Active Substances of Juniper Berries.

    Directory of Open Access Journals (Sweden)

    Agnieszka Joanna Brodowska

    Full Text Available The development of the parameters of ozone decontamination method assuring the least possible losses of biologically active substances (essential oils and polyphenols and their activity in common juniper (Juniperus communis (L. berries was studied. Ozone treatment in dynamic bed was conducted 9 times. The process was conducted under different ozone concentrations (100.0; 130.0; 160.0 g O3/m3 and times (30, 60, 90 min. After each decontamination, the microbiological profile of the juniper berries was studied, and the contaminating microflora was identified. Next to the microbiological profile, the phenolic profile, as well as antioxidant activity of extracts and essential oils were determined. The total polyphenol content (TPC, composition of essential oils, free radical-scavenging capacity, total antioxidant capacity, ferric-reducing antioxidant power (FRAP, beta-carotene bleaching test (BCB and LC-MS polyphenol analysis were carried out. The study reveals that during short ozone contact times, higher amounts of TPC, 15.47 and 12.91 mg CE/g of extract, for samples 100/30 and 130/30, respectively, were demonstrated. Whereas samples 100/60, 130/60, 100/90, and 160/90 exhibited the lowest amount of phenolics. The highest antioxidant activity was found in the methanol extract obtained from ozonated berries which exhibited the lowest IC50 in all the antioxidant assays, such as DPPH, FRAP, and BCB assays. Ozone treatment showed noteworthy potential and its usage in food manufacturing and as an alternative decontamination method should be considered.

  4. Estimating the impact of somatic cell count on the value of milk utilising parameters obtained from the published literature.

    Science.gov (United States)

    Geary, Una; Lopez-Villalobos, Nicolas; O'Brien, Bernadette; Garrick, Dorian J; Shalloo, Laurence

    2014-05-01

    The impact of mastitis on milk value per litre independent of the effect of mastitis on milk volume, was quantified for Ireland using a meta-analysis and a processing sector model. Changes in raw milk composition, cheese processing and composition associated with increased bulk milk somatic cell count (BMSCC) were incorporated into the model. Processing costs and market values were representative of current industry values. It was assumed that as BMSCC increased (i) milk fat and milk protein increased and milk lactose decreased, (ii) fat and protein recoveries decreased, (iii) cheese protein decreased and cheese moisture increased. Five BMSCC categories were examined from ⩽100 000 to >400 000 cells/ml. The analysis showed that as BMSCC increased the production quantities reduced. An increase in BMSCC from 100 000 to >400 000 cells/ml saw a reduction in net revenue of 3·2% per annum (€51·3 million) which corresponded to a reduction in the value of raw milk of €0·0096 cents/l.

  5. Olive oil pilot-production assisted by pulsed electric field: impact on extraction yield, chemical parameters and sensory properties.

    Science.gov (United States)

    Puértolas, Eduardo; Martínez de Marañón, Iñigo

    2015-01-15

    The impact of the use of pulsed electric field (PEF) technology on Arroniz olive oil production in terms of extraction yield and chemical and sensory quality has been studied at pilot scale in an industrial oil mill. The application of a PEF treatment (2 kV/cm; 11.25 kJ/kg) to the olive paste significantly increased the extraction yield by 13.3%, with respect to a control. Furthermore, olive oil obtained by PEF showed total phenolic content, total phytosterols and total tocopherols significantly higher than control (11.5%, 9.9% and 15.0%, respectively). The use of PEF had no negative effects on general chemical and sensory characteristics of the olive oil, maintaining the highest quality according to EU legal standards (EVOO; extra virgin olive oil). Therefore, PEF could be an appropriate technology to improve olive oil yield and produce EVOO enriched in human-health-related compounds, such as polyphenols, phytosterols and tocopherols. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Impact of a 'school-based' nutrition intervention on anthropometric parameters and the metabolic syndrome in Spanish adolescents.

    Science.gov (United States)

    Campos Pastor, M M; Serrano Pardo, M D; Fernández Soto, M L; Luna Del Castillo, J D; Escobar-Jiménez, F

    2012-01-01

    In adolescents, overweight and obesity are associated with an increased cardiovascular risk. The aim of this study was to determine the impact of a school-based nutritional education program (NEP) on lifestyle changes in Spanish adolescents. We selected 263 secondary school students (127 males) aged 12-16 years from Granada (Spain), who were followed up throughout 1 school year (2009-2010). At the beginning and end of the school year, data were gathered on the food consumption frequency, and anthropometric and biochemical profile. The NEP comprised a class on nutritional recommendations every 15 days, and administration of a daily breakfast of 275-350 kcal. After the intervention, the prevalence of overweight and obesity decreased among both male and female students (p metabolic syndrome (MS) from 32.2 to 19.7% (p < 0.001); in addition, body mass index was significantly decreased in normal weight, overweight and obesity groups (p = 0.001 and p = 0.02, respectively), and high-density-lipoprotein cholesterol and lean body mass was increased in all groups (p = 0.001). The NEP achieved a medium-term reduction in the prevalence of overweight and obesity and had a significant and positive effect on MS components in all groups. Copyright © 2012 S. Karger AG, Basel.

  7. Chironomus riparius exposure to fullerene-contaminated sediment results in oxidative stress and may impact life cycle parameters

    Energy Technology Data Exchange (ETDEWEB)

    Waissi, G.C., E-mail: greta.waissi@uef.fi [Department of Environmental and Biological Sciences, University of Eastern Finland, Joensuu (Finland); Bold, S. [GEOMAR Helmholtz Centre of Ocean for Research Kiel (Germany); Pakarinen, K.; Akkanen, J. [Department of Environmental and Biological Sciences, University of Eastern Finland, Joensuu (Finland); Leppänen, M.T. [Finnish Environment Institute, Jyväskylä (Finland); Petersen, E.J. [Material Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD (United States); Kukkonen, J.V.K. [University of Jyväskylä, Department of Biological and Environmental Science, Jyväskylä (Finland)

    2017-01-15

    Highlights: • FullerenesC{sub 60} were tested to C. riparius with acute and chronic exposures. • The rapid uptake of fullerenes by C. riparius observed after an acute experiment. • Oxidative stress was localized in tissues under microvilli layer. - Abstract: A key component of understanding the potential environmental risks of fullerenes (C{sub 60}) is their potential effects on benthic invertebrates. Using the sediment dwelling invertebrate Chironomus riparius we explored the effects of acute (12 h and 24 h) and chronic (10 d, 15 d, and 28 d) exposures of sediment associated fullerenes. The aims of this study were to assess the impact of exposure to C{sub 60} in the sediment top layer ((0.025, 0.18 and 0.48) C{sub 60} mg/cm{sup 2}) on larval growth, oxidative stress and emergence rates and to quantify larval body burdens in similarly exposed organisms. Oxidative stress localization was observed in the tissues next to the microvilli and exoskeleton through a method for identifying oxidative stress reactions generated by reactive oxygen species. Rapid intake of fullerenes was shown in acute experiments, whereas body residues decreased after chronic exposure. Transmission electron microscopy analysis revealed oxidative damage and structural changes in cells located between the lipid droplets and next to the microvilli layer in fullerene exposed samples. Fullerene associated sediments also caused changes in the emergence rate of males and females, suggesting that the cellular interactions described above or other effects from the fullerenes may influence reproduction rates.

  8. Longitudinal assessment of the impact of multiple switches between a biosimilar and its reference product on efficacy parameters.

    Science.gov (United States)

    Mielke, Johanna; Woehling, Heike; Jones, Byron

    2018-02-08

    Patients, physicians, and health care providers in Europe have more than 10 years of experience with biosimilars. However, there are still debates if switching between a biosimilar and its reference product influences the efficacy of the treatment. In this paper, we address this uncertainty by developing a formal statistical test that can be used for showing that switching has no negative impact on the efficacy of biosimilars. For that, we first introduce a linear mixed-effects model that is used for defining the null hypothesis (switching influences the efficacy) and the alternative hypothesis (switching has no influence on the efficacy). Using this as the foundation of our work, we propose several approaches for testing for changes in the efficacy of the treatment due to switching and discuss the properties of these tests in an extensive simulation study. It is shown that all these methods have advantages and disadvantages and the decision regarding which method is preferred depends on the expectation of a switching assessment. To demonstrate the applicability of the methods in practice, the approaches were applied to the data of the EGALITY study, which compares the reference product Enbrel® (Amgen) with the approved biosimilar Erelzi® (Sandoz). Copyright © 2018 John Wiley & Sons, Ltd.

  9. A Simulation Based Analysis of The Impact of IEEE 802.15.4 MAC Parameters on the Performance Under Different Traffic Loads

    Directory of Open Access Journals (Sweden)

    D. Rohm

    2009-01-01

    Full Text Available IEEE 802.15.4, a MAC/PHY protocol for low power and low data rate wireless networks, is emerging as the popular choice for various monitoring and control applications. Depending on the application, the traffic load on an IEEE 802.15.4 network may vary over a wide range. The performance of the protocol, measured in terms of the packet loss probability and the packet latency, depends upon the prevailing traffic load among the nodes competing for channel access, the level of interference from the hidden nodes and the configuration of IEEE 802.15.4 MAC parameters. In this paper, we analyze via simulations the impact of different configurable MAC parameters on the performance of beaconless IEEE 802.15.4 networks under different traffic loads and under different levels of interference from the hidden nodes. Based on this analysis, we suggest the values of IEEE 802.15.4 MAC parameters that results in a good tradeoff between the packet loss probability and the packet latency under different conditions.

  10. Impact of Early Release of the IVC Clamp from Different IVC Clamping Maneuvers on Changes in Hemodynamic Parameters in Living Donor Liver Transplantation.

    Science.gov (United States)

    Shih, Tsung-Hsiao; Huang, Chia-Jung; Chen, Chao-Long; Cheng, Kwok-Wai; Wu, Shao-Chun; Yang, Sheng-Chun; Juang, Sin-Ei; Lee, Ying-En; Jawan, Bruno; Wang, Chih-Hsien

    2015-09-06

    BACKGROUND The aim of this study was to evaluate the impact of different methods of inferior vena cava (IVC) clamping and release of the cross clamp on hemodynamic parameters of recipients during living donor liver transplantation. MATERIAL AND METHODS Ninety-six adult living donor liver transplantation patients were divided into 3 groups according to cross-clamp of the IVC for all the hepatic vein and portal vein reconstruction (G1), cross-clamp of the IVC only for hepatic vein reconstruction (G2), and side-clamp of the IVC for hepatic vein reconstruction (G3). In G2 and G2, the reconstructed hepatic vein was clamped instead of the IVC for portal vein reconstruction. The hemodynamic parameters among groups were compared by 1-way ANOVA and the complications in each group were compared using the Kruskal-Wallis test. RESULTS Changes in percentage of MAP and CO in G3 were significantly less than that of G1 and G2 for hepatic vein reconstruction. Hemodynamic parameters of G2 and G3 normalized to pre-clamped values during portal vein reconstruction, while the hemodynamics of G1 remained unstable. CONCLUSIONS Hemodynamic changes were less pronounced in LT with side-clamp of the inferior cava vein versus total cross-clamp. Early release of the IVC clamp minimized the hemodynamic changes. There were no differences in terms of outcome (morbidity and mortality).

  11. Impact of gingivitis treatment for diabetic patients on quality of life related to periodontal objective parameters: A randomized controlled clinical trial.

    Science.gov (United States)

    Cortelli, Sheila C; Costa, Fernando O; Gargioni-Filho, Antonio; Aquino, Davi R; Cota, Luis O M; Scherma, Alexandre P; Miranda, Taís B; Cortelli, Jose R

    2018-02-01

    Patients with diabetes have a poor oral health-related quality of life (OHRQoL). It is not clear if this situation could be changed with effective periodontal treatment. This study examined both patients with diabetes and systemically healthy individuals to discover the impact of a gingivitis treatment protocol on OHRQoL and its relation to objective periodontal parameters. After ultrasonic debridement, patients were randomly assigned to an essential-oils (EO) or placebo mouthwash group. At baseline and 3 months, OHRQoL was assessed with the Oral Health and Quality of Life-United Kingdom questionnaire (OHQoL-UK) along with clinical, halitometric, microbiological and inflammatory objective parameters. The primary outcome was a change in OHQoL-UK scores. A factor analysis was performed and the impact of the extracted quality of life factor (QLF) and its interactions with diabetes, treatment, and time on the objective parameters, were tested by multiple linear regression models (p oral health status on quality of life increased in EO groups but not in placebo groups. Question I (self-confidence) showed the greatest factorial weight, while Question A (food intake) showed the lowest factorial weight. All patients who showed OHRQoL improvements and used the EO rinse showed the lowest plaque and gingival indices and lower levels of bacteria and volatile sulfur compounds. OHRQoL positively changed overtime. Most effective treatment protocols would provide better improvements in OHRQoL which is related to periodontal objective measures. Copyright © 2017. Published by Elsevier Ltd.

  12. LIGO: The strong belief

    CERN Multimedia

    Antonella Del Rosso

    2016-01-01

    Twenty years of designing, building and testing a number of innovative technologies, with the strong belief that the endeavour would lead to a historic breakthrough. The Bulletin publishes an abstract of the Courier’s interview with Barry Barish, one of the founding fathers of LIGO.   The plots show the signals of gravitational waves detected by the twin LIGO observatories at Livingston, Louisiana, and Hanford, Washington. (Image: Caltech/MIT/LIGO Lab) On 11 February, the Laser Interferometer Gravitational-Wave Observatory (LIGO) and Virgo collaborations published a historic paper in which they showed a gravitational signal emitted by the merger of two black holes. These results come after 20 years of hard work by a large collaboration of scientists operating the two LIGO observatories in the US. Barry Barish, Linde Professor of Physics, Emeritus at the California Institute of Technology and former Director of the Global Design Effort for the Internat...

  13. Composition and structure of the larval fish community related to environmental parameters in a tropical estuary impacted by climate change

    Science.gov (United States)

    Sloterdijk, Hans; Brehmer, Patrice; Sadio, Oumar; Müller, Hanno; Döring, Julian; Ekau, Werner

    2017-10-01

    Mangrove ecosystems have long been considered essential habitats and are commonly viewed and referred to as "nursery areas". They are highly sensitive to climate change, and environmental transformations in these ecosystems are expected. The Sine Saloum estuary is a case of a system affected by global climate change where reduced precipitation and temperature increase have resulted in an inversion of the salinity gradient. Within the estuary, the composition and structure of the larval fish community related to environmental parameters were investigated using neuston and ring trawl nets. Larval fishes were sampled at 16 stations distributed along a salinity and distance-to-the-sea gradient during four field campaigns (November 2013, February, June, and August 2014) covering an annual cycle. This is the first study documenting the spatial and temporal assemblages of fish larvae in an inverse estuary. The total of 41 taxa representing 24 families and 34 genus identified in this study was lower than that of other tropical estuaries. Clupeidae spp. was the dominant taxon, accounting for 28.9% of the total number of fish larvae caught, followed by Gerreidae spp. (21.1%), Hyporamphus picarti (18.8%), Diplodus bellottii (8.9%), Hypleurochilus langi (4.8%), Mugilidae spp. (4.4%), and Gobiidae sp.1 (3.5%). A total of 20 taxa were recorded within the upper estuary region, whereas 29 and 37 taxa were observed in the middle and lower reaches, respectively. While larval fish were captured at all sites and during all seasons, abundances and richness decreased with increasing salinity. Larval fish assemblages also showed a clear vertical structure corresponding to three distinct water strata. Salinity, water temperature, and dissolved oxygen were the variables that best explained the spatial and temporal differences in larval fish assemblages. It is difficult to forecast the future situation for this system but so far, compared to other mangrove estuarine systems, we have

  14. Impact of hydrographic parameters and seasonal variation in sediment fluxes on coral status at Chumbe and Bawe reefs, Zanzibar, Tanzania

    Science.gov (United States)

    Muzuka, Alfred N. N.; Dubi, Alfonse M.; Muhando, Christopher A.; Shaghude, Yohanna W.

    2010-09-01

    Coral reefs which are an important resource to coastal communities and nation at large are adversely affected by rate of sediment flux to the reefs. However, there is little information on seasonal trend in sediment flux and its impact at the reefs off Zanzibar. Two years' monthly data on sedimentation at Chumbe and Bawe reefs were used to assess seasonal variability in sediment flux and its implication on the coral status. Sediment flux to the Bawe reefs for the duration of the study ranged from 0.2 to 41.5 mg cm -2 d -1, while it ranged from 0.8 to 65.8 mg cm -2 d -1 at the Chumbe reefs. Sediment fluxes at Bawe reefs were highest between November and March, while they were highest between April and September at Chumbe reefs. Generally, sediment fluxes at Bawe reefs were low compared to those at Chumbe. The total sediment input to the reefs ranged from 4615 to 123,403 kg d -1 for Bawe reefs and 2750 to 79,636 kg d -1 for Chumbe reefs. High sediment fluxes at Bawe reefs between November and March; and the Chumbe reefs between April and September can be attributed to water currents and wind pattern in the east African region which are under the influence of the monsoons. The observed trend suggests that the period for coral transplant as a management option for the two sites should be different. Coral transplant can be undertaken in such a way that stress of the corals due to sedimentation can be felt after they have overcome stress from transplant process and temperature. The results from this study contribute to the much needed information for coral transplant, restoration, and management.

  15. Impact of a behaviorally-based weight loss intervention on parameters of insulin resistance in breast cancer survivors.

    Science.gov (United States)

    Dittus, Kim L; Harvey, Jean R; Bunn, Janice Y; Kokinda, Nathan D; Wilson, Karen M; Priest, Jeff; Pratley, Richard E

    2018-03-27

    Breast cancer survivors with excess weight are more likely to have negative breast cancer outcomes. Biomarkers related to insulin resistance may help explain this negative association. Weight loss is associated with improvements in insulin sensitivity. Our goal was to identify the impact of a behaviorally based weight loss intervention on indices of insulin resistance. Overweight, early stage breast cancer survivors who completed initial cancer therapy were enrolled in a 6 month behaviorally based weight loss intervention that included calorie reduction, exercise and behavior modification. Biomarkers related to insulin resistance were obtained at baseline and after the intervention. Results from participants who achieved ≥5% weight loss were compared to those who lost less weight. Despite not having diabetes as a preexisting diagnosis prior to the study, 69% of all participants were considered to have pre-diabetes or diabetes at baseline based on American Diabetes Association definitions. Participants who achieved ≥5% weight loss had significantly lower fasting insulin, AUC insulin, and insulin resistance as measured by HOMA-IR. Beta cell function decreased as anticipated when insulin resistance improved. Additionally, leptin levels declined. Breast cancer survivors who achieved ≥5% weight loss demonstrated significant improvements in indices of insulin resistance. Despite an exclusion criteria of diabetes at the time of enrolment, a high proportion met criteria for pre-diabetes or diabetes at baseline. Pre-diabetes appears to be under recognized in overweight breast cancer survivors. Behaviorally based weight loss interventions can result in weight loss and improvements in biomarkers related to breast cancer outcomes and additionally may decrease the chance of developing diabetes. NCT01482702 4/12/2010 (retrospectively registered).  https://clinicaltrials.gov/ct2/show/NCT01482702?term=Dittus&rank=4.

  16. Impact of image denoising on image quality, quantitative parameters and sensitivity of ultra-low-dose volume perfusion CT imaging

    Energy Technology Data Exchange (ETDEWEB)

    Othman, Ahmed E. [RWTH Aachen University, Department of Diagnostic and Interventional Neuroradiology, Aachen (Germany); Eberhard Karls University Tuebingen, University Hospital Tuebingen, Department for Diagnostic and Interventional Radiology, Tuebingen (Germany); Brockmann, Carolin; Afat, Saif; Pjontek, Rastislav; Nikoubashman, Omid; Brockmann, Marc A.; Wiesmann, Martin [RWTH Aachen University, Department of Diagnostic and Interventional Neuroradiology, Aachen (Germany); Yang, Zepa; Kim, Changwon [Seoul National University, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Suwon (Korea, Republic of); Seoul National University College of Medicine, Department of Radiology, Seoul (Korea, Republic of); Nikolaou, Konstantin [Eberhard Karls University Tuebingen, University Hospital Tuebingen, Department for Diagnostic and Interventional Radiology, Tuebingen (Germany); Kim, Jong Hyo [Seoul National University, Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Suwon (Korea, Republic of); Seoul National University College of Medicine, Department of Radiology, Seoul (Korea, Republic of); Advanced Institute of Convergence Technology, Center for Medical-IT Convergence Technology Research, Suwon (Korea, Republic of); Seoul National University Hospital, Department of Radiology, Seoul (Korea, Republic of)

    2016-01-15

    To examine the impact of denoising on ultra-low-dose volume perfusion CT (ULD-VPCT) imaging in acute stroke. Simulated ULD-VPCT data sets at 20 % dose rate were generated from perfusion data sets of 20 patients with suspected ischemic stroke acquired at 80 kVp/180 mAs. Four data sets were generated from each ULD-VPCT data set: not-denoised (ND); denoised using spatiotemporal filter (D1); denoised using quanta-stream diffusion technique (D2); combination of both methods (D1 + D2). Signal-to-noise ratio (SNR) was measured in the resulting 100 data sets. Image quality, presence/absence of ischemic lesions, CBV and CBF scores according to a modified ASPECTS score were assessed by two blinded readers. SNR and qualitative scores were highest for D1 + D2 and lowest for ND (all p ≤ 0.001). In 25 % of the patients, ND maps were not assessable and therefore excluded from further analyses. Compared to original data sets, in D2 and D1 + D2, readers correctly identified all patients with ischemic lesions (sensitivity 1.0, kappa 1.0). Lesion size was most accurately estimated for D1 + D2 with a sensitivity of 1.0 (CBV) and 0.94 (CBF) and an inter-rater agreement of 1.0 and 0.92, respectively. An appropriate combination of denoising techniques applied in ULD-VPCT produces diagnostically sufficient perfusion maps at substantially reduced dose rates as low as 20 % of the normal scan. (orig.)

  17. Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review.

    Science.gov (United States)

    Kämmerer, Peer W; Schneider, Daniel; Schiegnitz, Eik; Schneider, Sarah; Walter, Christian; Frerich, Bernhard; Kunkel, Martin

    2016-09-01

    Odontoma-separated into complex (CxOD) and compound (CpOD) subtypes-represents the most frequent odontogenic malformation. Retention of permanent teeth is a common symptom. Therefore, in a series of odontomas, an analysis of the management of retained teeth was conducted. In a retrospective multicenter study of two University Medical Centers and one private praxis in Germany, demographic and clinical data regarding odontomas from 01/2000-03/2015 were obtained. In particular, the influence of operative therapy on the dentition and on the treatment of impacted teeth was analyzed. Forty-five patients with 15 CxOD and 30 CpOD were included. Initial symptoms were delayed eruption of permanent teeth (n = 11), pain (n = 4), and swellings (n = 2); 28 cases were discovered by incidence, all of them via panoramic radiographs. The mandible/maxilla ratio was about 1:0.55 (29/16). Thirty-five out of 45 odontomas were in close proximity of at least one tooth (n = 16 at molars). A total of 14 teeth were extracted (CxOD: n = 5; CpOD: n = 9). Extractions had to be conducted more often in older patients (mean age 39.8 vs. 25.6 years). Of the non-extracted teeth, 8 teeth were displaced and retained. Of those, 4 teeth were aligned in the dental arch via orthodontic help and 2 teeth erupted spontaneously after operation during the follow-up period. In all cases, no relapse was seen. Odontomas can cause displacement as well as malformation and resorption of the adjacent teeth. Mostly, removal of odontomas is conducted. Extirpation of odontoma can allow for normal tooth eruption, often rendering extractions avoidable. Orthodontic alignment, though sometimes challenging, is a reasonable therapeutic option. These findings underline the value of the panoramic radiograph in preventive dentistry in younger patients.

  18. Correlation study of some physico-chemical parameters and benthic macroinvertebrates metrics on the ecological impacts of flriculture industries along Wedecha River, Debrezeit, Ethiopia

    Directory of Open Access Journals (Sweden)

    Sisay Misganaw Tamiru

    2017-10-01

    Full Text Available Objective: To assess the quality of water using biological and chemical information correlation study. Methods: A total of 6 sites, one reference site less impaired to represent natural conditions from upstream, and 5 impaired sites in the downstream were sampled for macroinvertebrates and physicochemical parameters. Results: In the polluted sites with high nutrient enrichment and organic loading, only organisms with special physiological and morphological adaptations were found, such as Hydrobiidae, Physidae and Viviparidae snails. Physicochemical parameters: electrical conductivity, chemical oxygen demand, biological oxygen demand, sulphate, orthophosphate and nitrate-nitrogen and metrics: percent of Mollusca, percent of Physidae and percent of dominant taxa were used for monitoring, and expected to have strong positive relation with increasing disturbance. Conclusions: Therefore, floriculture industries wastewater discharged to the nearby rivers has enormous effect on the degradation of the ecosystem. To sustain the ecological conditions of the nearby rivers, wastewater treatment and environmental audit were suggested. Environmental assessment and environmental audit enable the floriculturist to keep humans and the environment safe. Taking care of workers, soil, water and the environment has to be seen with great care and caution because it is difficult to maintain a healthy community and carry out development in a degraded environment.

  19. Characteristics and Impact Factors of Parameter Alpha in the Nonlinear Advection-Aridity Method for Estimating Evapotranspiration at Interannual Scale in the Loess Plateau

    Science.gov (United States)

    Zhou, H.; Liu, W.; Ning, T.

    2017-12-01

    Land surface actual evapotranspiration plays a key role in the global water and energy cycles. Accurate estimation of evapotranspiration is crucial for understanding the interactions between the land surface and the atmosphere, as well as for managing water resources. The nonlinear advection-aridity approach was formulated by Brutsaert to estimate actual evapotranspiration in 2015. Subsequently, this approach has been verified, applied and developed by many scholars. The estimation, impact factors and correlation analysis of the parameter alpha (αe) of this approach has become important aspects of the research. According to the principle of this approach, the potential evapotranspiration (ETpo) (taking αe as 1) and the apparent potential evapotranspiration (ETpm) were calculated using the meteorological data of 123 sites of the Loess Plateau and its surrounding areas. Then the mean spatial values of precipitation (P), ETpm and ETpo for 13 catchments were obtained by a CoKriging interpolation algorithm. Based on the runoff data of the 13 catchments, actual evapotranspiration was calculated using the catchment water balance equation at the hydrological year scale (May to April of the following year) by ignoring the change of catchment water storage. Thus, the parameter was estimated, and its relationships with P, ETpm and aridity index (ETpm/P) were further analyzed. The results showed that the general range of annual parameter value was 0.385-1.085, with an average value of 0.751 and a standard deviation of 0.113. The mean annual parameter αe value showed different spatial characteristics, with lower values in northern and higher values in southern. The annual scale parameter linearly related with annual P (R2=0.89) and ETpm (R2=0.49), while it exhibited a power function relationship with the aridity index (R2=0.83). Considering the ETpm is a variable in the nonlinear advection-aridity approach in which its effect has been incorporated, the relationship of

  20. Measurements of event properties and multi-differential jet cross sections and impact of CMS measurements on Proton Structure and QCD parameters

    CERN Document Server

    Kaur, Anterpreet

    2017-01-01

    We present results on the measurements of characteristics of events with jets including jet-charge, investigations of shapes and jet mass distributions. The measurements are compared to theoretical predictions including those matched to parton shower and hadronization. Multi-differential jet cross sections are also presented over a wide range in transverse momenta from inclusive jets to multi-jet final states. These measurements have an impact on the determination of the strong coupling constant as well as on parton distribution functions (PDFs) and are helpful in the treatment of heavy flavours in QCD analyses. We also show angular correlations in multi-jet events at highest center-of-mass energies and compare the measurements to theoretical predictions including higher order parton radiation and coherence effects. Measurements of cross sections of jet and top-quark pair production are in particular sensitive to the gluon distribution in the proton, while the electroweak boson production - inclusive or asso...

  1. John Strong (1941 - 2006)

    CERN Multimedia

    Wickens, F

    Our friend and colleague John Strong was cruelly taken from us by a brain tumour on Monday 31st July, a few days before his 65th birthday John started his career working with a group from Westfield College, under the leadership of Ted Bellamy. He obtained his PhD and spent the early part of his career on experiments at Rutherford Appleton Laboratory (RAL), but after the early 1970s his research was focussed on experiments in CERN. Over the years he made a number of notable contributions to experiments in CERN: The Omega spectrometer adopted a system John had originally developed for experiments at RAL using vidicon cameras to record the sparks in the spark chambers; He contributed to the success of NA1 and NA7, where he became heavily involved in the electronic trigger systems; He was responsible for the second level trigger system for the ALEPH detector and spent five years leading a team that designed and built the system, which ran for twelve years with only minor interventions. Following ALEPH he tur...

  2. Stirring Strongly Coupled Plasma

    CERN Document Server

    Fadafan, Kazem Bitaghsir; Rajagopal, Krishna; Wiedemann, Urs Achim

    2009-01-01

    We determine the energy it takes to move a test quark along a circle of radius L with angular frequency w through the strongly coupled plasma of N=4 supersymmetric Yang-Mills (SYM) theory. We find that for most values of L and w the energy deposited by stirring the plasma in this way is governed either by the drag force acting on a test quark moving through the plasma in a straight line with speed v=Lw or by the energy radiated by a quark in circular motion in the absence of any plasma, whichever is larger. There is a continuous crossover from the drag-dominated regime to the radiation-dominated regime. In the crossover regime we find evidence for significant destructive interference between energy loss due to drag and that due to radiation as if in vacuum. The rotating quark thus serves as a model system in which the relative strength of, and interplay between, two different mechanisms of parton energy loss is accessible via a controlled classical gravity calculation. We close by speculating on the implicati...

  3. Strong-interaction nonuniversality

    International Nuclear Information System (INIS)

    Volkas, R.R.; Foot, R.; He, X.; Joshi, G.C.

    1989-01-01

    The universal QCD color theory is extended to an SU(3) 1 direct product SU(3) 2 direct product SU(3) 3 gauge theory, where quarks of the ith generation transform as triplets under SU(3)/sub i/ and singlets under the other two factors. The usual color group is then identified with the diagonal subgroup, which remains exact after symmetry breaking. The gauge bosons associated with the 16 broken generators then form two massive octets under ordinary color. The interactions between quarks and these heavy gluonlike particles are explicitly nonuniversal and thus an exploration of their physical implications allows us to shed light on the fundamental issue of strong-interaction universality. Nonuniversality and weak flavor mixing are shown to generate heavy-gluon-induced flavor-changing neutral currents. The phenomenology of these processes is studied, as they provide the major experimental constraint on the extended theory. Three symmetry-breaking scenarios are presented. The first has color breaking occurring at the weak scale, while the second and third divorce the two scales. The third model has the interesting feature of radiatively induced off-diagonal Kobayashi-Maskawa matrix elements

  4. SATELLITE CONSTELLATION DESIGN PARAMETER

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. SATELLITE CONSTELLATION DESIGN PARAMETER. 1. ORBIT CHARACTERISTICS. ORBITAL HEIGHT >= 20,000 KM. LONGER VISIBILITY; ORBITAL PERIOD. PERTURBATIONS(MINIMUM). SOLAR RADIATION PRESSURE (IMPACTS ECCENTRICITY); LUNI ...

  5. Single and Combined Impacts of Vitamin A and Selenium in Diet on Productive Performance, Egg Quality, and Some Blood Parameters of Laying Hens During Hot Season.

    Science.gov (United States)

    Abd El-Hack, Mohamed E; Mahrose, Khalid; Askar, Ali A; Alagawany, Mahmoud; Arif, Muhammad; Saeed, Muhammad; Abbasi, Farzana; Soomro, Rab Nawaz; Siyal, Farman Ali; Chaudhry, Maria Tabassum

    2017-05-01

    A study was conducted using 162 Bovans laying hens to investigate the impacts of extra dietary vitamin A (0, 8000, 16,000 IU/kg), selenium (0, 0.25, 0.50 mg/kg), and their combinations on the performance, egg quality, and blood biological parameters of laying hens during summer months. Supplemental vitamin A up to 16,000 IU/kg diet significantly (P feed intake which increased with 8000 IU/kg diet compared with control. Feed intake and feed conversion of hens fed diet supplemented with selenium revealed high statistical (P = 0.001) differences. All egg quality criteria were not significantly (P hens reared under heat stress conditions.

  6. Production of nitrogen oxide gases from an oxic/anoxic process via nitrite: influence of liquid parameters and impact on mass balance.

    Science.gov (United States)

    Eusebi, Anna Laura; Santinelli, Martina; Battistoni, Paolo

    2015-01-01

    The produced nitrogen oxides from the biological treatment of swine and dairy anaerobic supernatant are evaluated. The quantification of the emissions has been conducted in a continuous way and coupled with batch tests to determine the mechanisms of formation. Using a continuous monitoring system, N2O and NO forms are present in higher quantities than NO2. The elevated emissions are linked with the increment of the influent nitrogen load both in the daily variations and in the long period. The NH4-N and NO2-N accumulations are recognized as the main parameters which determine the great nitrogen oxide emissions even at dissolved oxygen concentration of around 2 mgL(-1). The nitrogen oxides' impacts are between 0.0034 and 0.0044N% for the N2O and between 0.0020 and 0.0026N% for NO. A strict dependence between the N2O and the oxidation reduction potential is found.

  7. Impact of the Xba1-polymorphism of the human muscle glycogen synthase gene on parameters of the insulin resistance syndrome in a Danish twin population

    DEFF Research Database (Denmark)

    Fenger, M; Poulsen, P; Beck-Nielsen, H

    2000-01-01

    : The Xba1-polymorphism of the human muscle glycogen synthase gene is correlated to insulin resistance and to diastolic blood pressure. The polymorphism does not involve any known transcription factor or any structural change in GYS1, and these correlations are therefore most probably caused by linkage......AIMS: To establish the impact on the insulin resistance syndrome of the intron 14 Xba1-polymorphism in human muscle glycogen synthase (GYS1). METHODS: Parameters related to the insulin resistance syndrome were measured in 244 monozygotic twins and 322 dizygotic twins with or without impaired...... and the remainder had the genotype A1A2. No A2A2-genotypes were detected. In 11 genotypic discordant dizygotic twin pairs the insulin resistance was significantly increased in the twins carrying the A1A2 genotype regardless of sex (HOMA index 1.81 (A1A1) vs. 2.57 (A1A2), P

  8. A measurement of [Gamma](Z[sup 0] [yields]b anti b) / [Gamma](Z[sup 0] [yields]hadrons) using an impact parameter technique

    Energy Technology Data Exchange (ETDEWEB)

    Acton, P.D.; Akers, R.; Alexander, G.; Allison, J.; Anderson, K.J.; Arcelli, S.; Astbury, A.; Axen, D.; Azuelos, G.; Baines, J.T.M.; Ball, A.H.; Banks, J.; Barlow, R.J.; Barnett, S.; Bartoldus, R.; Batley, J.R.; Beaudoin, G.; Beck, A.; Beck, G.A.; Becker, J.; Beeston, C.; Behnke, T.; Bell, K.W.; Bella, G.; Bentkowski, P.; Berlich, P.; Bethke, S.; Biebel, O.; Bloodworth, I.J.; Bock, P.; Boden, B.; Bosch, H.M.; Boutemeur, M.; Breuker, H.; Bright-Thomas, P.; Brown, R.M.; Buijs, A.; Burckhart, H.J.; Burgard, C.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, D.G.; Chu, S.L.; Clarke, P.E.L.; Clayton, J.C.; Cohen, I.; Conboy, J.E.; Cooper, M.; Coupland, M.; Cuffiani, M.; Dado, S.; Dallavalle, G.M.; De Jong, S.; Del Pozo, L.A.; Deng, H.; Dieckmann, A.; Dittmar, M.; Dixit, M.S.; Do Couto e Silva, E.; Duboscq, J.E.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Dumas, D.J.P.; Elcombe, P.A.; Estabrooks, P.G.; Etzion, E.; Evans, H.G.; Fabbri, F.; Fabbro, B.; Fierro; OPAL Collaboration

    1993-12-01

    The fractional partial width of the Z[sup 0] to b quarks, [Gamma]sub(b anti b)/[Gamma][sub had], has been measured by OPAL using an impact parameter technique. The method has been developed using 130 000 hadronic events collected by OPAL in 1990. We find: [Gamma]sub(b anti b)/[Gamma][sub had]=0.222[+-]0.007(stat)[+-]0.008(sys). The measurement assumes the relative rates of the Z[sup 0] to uds and c quarks given by the Standard Model. Varying the charm fraction from the Standard Model value of [Gamma]sub(c anti c)/[Gamma][sub had]=0.171 changes the result by an additional [Delta][Gamma]sub(b anti b)/[Gamma]sub(b anti b)=-0.135x[Delta][Gamma]sub(c anti c)/[Gamma]sub(c anti c). (orig.)

  9. Prognostic value of 18F-FDG PET image-based parameters in oesophageal cancer and impact of tumour delineation methodology

    International Nuclear Information System (INIS)

    Hatt, Mathieu; Visvikis, Dimitris; Tixier, Florent; Albarghach, Nidal M.; Pradier, Olivier; Cheze-le Rest, Catherine

    2011-01-01

    18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET) image-derived parameters, such as standardized uptake value (SUV), functional tumour length (TL) and tumour volume (TV) or total lesion glycolysis (TLG), may be useful for determining prognosis in patients with oesophageal carcinoma. The objectives of this work were to investigate the prognostic value of these indices in oesophageal cancer patients undergoing combined chemoradiotherapy treatment and the impact of TV delineation strategies. A total of 45 patients were retrospectively analysed. Tumours were delineated on pretreatment 18 F-FDG scans using adaptive threshold and automatic (fuzzy locally adaptive Bayesian, FLAB) methodologies. The maximum standardized uptake value (SUV max ), SUV peak , SUV mean , TL, TV and TLG were computed. The prognostic value of each parameter for overall survival was investigated using Kaplan-Meier and Cox regression models for univariate and multivariate analyses, respectively. Large differences were observed between methodologies (from -140 to +50% for TV). SUV measurements were not significant prognostic factors for overall survival, whereas TV, TL and TLG were, irrespective of the segmentation strategy. After multivariate analysis including standard tumour staging, only TV (p < 0.002) and TL (p = 0.042) determined using FLAB were independent prognostic factors. Whereas no SUV measurement was a significant prognostic factor, TV, TL and TLG were significant prognostic factors for overall survival, irrespective of the delineation methodology. Only functional TV and TL derived using FLAB were independent prognostic factors, highlighting the need for accurate and robust PET tumour delineation tools for oncology applications. (orig.)

  10. Whole-Organ CT Perfusion of the Pancreas: Impact of Iterative Reconstruction on Image Quality, Perfusion Parameters and Radiation Dose in 256-Slice CT-Preliminary Findings

    Science.gov (United States)

    Xie, Qian; Wu, Juan; Tang, Ying; Dou, Yafang; Hao, Sijie; Xu, Feijia; Feng, Xiaoyuan; Liang, Zonghui

    2013-01-01

    Background This study was performed to assess whether iterative reconstruction can reduce radiation dose while maintaining acceptable image quality, and to investigate whether perfusion parameters vary from conventional filtered back projection (FBP) at the low-tube-voltage (80-kVp) during whole-pancreas perfusion examination using a 256-slice CT. Methods 76 patients with known or suspected pancreatic mass underwent whole-pancreas perfusion by a 256-slice CT. High- and low-tube-voltage CT images were acquired. 120-kVp image data (protocol A) and 80-kVp image data (protocol B) were reconstructed with conventional FBP, and 80-kVp image data were reconstructed with iDose4 (protocol C) iterative reconstruction. The image noise; contrast-to-noise ratio (CNR) relative to muscle for the pancreas, liver, and aorta; and radiation dose of each protocol were assessed quantitatively. Overall image quality was assessed qualitatively. Among 76 patients, 23 were eventually proven to have a normal pancreas. Perfusion parameters of normal pancreas in each protocol including blood volume, blood flow, and permeability-surface area product were measured. Results In the quantitative study, protocol C reduced image noise by 36.8% compared to protocol B (Pperfusion values among three different protocols. Conclusion Low-tube-voltage and iDose4 iterative reconstruction can dramatically decrease the radiation dose with acceptable image quality during whole-pancreas CT perfusion and have no significant impact on the perfusion parameters of normal pancreas compared to the conventional FBP reconstruction using a 256-slice CT scanner. PMID:24303017

  11. Aperture averaging in strong oceanic turbulence

    Science.gov (United States)

    Gökçe, Muhsin Caner; Baykal, Yahya

    2018-04-01

    Receiver aperture averaging technique is employed in underwater wireless optical communication (UWOC) systems to mitigate the effects of oceanic turbulence, thus to improve the system performance. The irradiance flux variance is a measure of the intensity fluctuations on a lens of the receiver aperture. Using the modified Rytov theory which uses the small-scale and large-scale spatial filters, and our previously presented expression that shows the atmospheric structure constant in terms of oceanic turbulence parameters, we evaluate the irradiance flux variance and the aperture averaging factor of a spherical wave in strong oceanic turbulence. Irradiance flux variance variations are examined versus the oceanic turbulence parameters and the receiver aperture diameter are examined in strong oceanic turbulence. Also, the effect of the receiver aperture diameter on the aperture averaging factor is presented in strong oceanic turbulence.

  12. Experimental and statistical models of impact determination of the electron beam parameters on surface layers properties of optical elements in precision instruments building

    Directory of Open Access Journals (Sweden)

    I.V. Yatsenko

    2016-05-01

    external heat flows in 1.3...1.5 times higher than before treatment. Conclusions: As results of the research the experimental and statistical models to determine the impact of parameters of the electron beam on the basic properties of the surface layers of the optical elements and their resistance to thermal action have been developed. This makes it possible (with a relative error of 5 ... 9% automatically in real time to form a managed database with improved properties that impact on the technical and operational characteristics of optical components and devices based on them.

  13. Impact of anthropogenic activities on physico-chemical parameters of water and mineral uptake in Catla catla from river Ravi, Pakistan.

    Science.gov (United States)

    Shakir, Abdullah; Chaudhry, Abdul Shakoor; Qazi, Javed Iqbal

    2013-03-01

    The river Ravi, while passing through Lahore, the second largest city of Pakistan, gets highly polluted owning heavy loads of untreated municipal sewage and industrial effluents of diverse kinds. The fish, Catla catla sampled in two different seasons from three downstream polluted sites were compared with the samples of the same fish from an upstream, a less polluted site, for their physico-chemical parameters. The data were statistically analysed to study the effect of sites, seasons and their interaction on the physico-chemical parameters of waters and mineral uptake in fish muscles. Significant differences (P river appeared to be polluted as indicated by the high values of total suspended solids (909 mg/l) and sulphate (964 mg/l) in comparison to the respective values of 150 and 600 mg/l being suggested as the safer values of drinking water of the National Environmental Quality Standards. Most trace and macro elements in fish muscles were increased with the increasing pollution loads from the upstream to the downstream sites of this river. The remarkable increases in the levels of all the investigated minerals in fish muscles from the polluted sites raise concerns about the long-term health of the river Ravi ecosystem and consequently the fish and its consumer's health. The results contradict the opinion of the local population that the riverine fish are natural, more health-promoting and precious than the pond fish. Therefore, we strongly argue for the utilization of an effect-based monitoring approach to alleviate the detrimental effects of anthropogenic activities on fish and the fish consumers' health.

  14. Methodologies, models and parameters for environmental, impact assessment of hazardous and radioactive contaminants; Metodologias, modelos y parametros para evaluacion del impacto ambiental de contaminantes peligrosos y radiactivos

    Energy Technology Data Exchange (ETDEWEB)

    Aguero, A.; Cancio, D.; Garcia-Olivares, A.; Romero, L.; Pinedo, P.; Robles, B.; Rodriguez, J.; Simon, I.; Suanez, A.

    2003-07-01

    An Environmental Impact Assessment Methodology to assess the impact arising from contaminants present in hazardous and radioactive wastes has been developed. Taking into account of the background information on legislation, waste categories and contaminants inventory, and disposal, recycling and waste treatment options, an Environmental Impact Assessment Methodology (MEIA) is proposed. This is applicable to (i) several types of solid wastes (hazardous, radioactive and mixed wastes; (ii) several management options (recycling and temporal and final storage (in shallow and deep disposal)), (iii) several levels of data availability. Conceptual and mathematical models and software tools needed for the application of the MEIA have been developed. Bearing in mind that this is a complex process, both the models and tools have to be developed following an iterative approaches, involving refinement of the models and go as to better correspond the described system. The selection of suitable parameters for the models is based on information derived from field and laboratory measurements and experiments, nd then applying a data elicitation protocol.. It is shown an application performed for a hypothetical shallow radioactive waste disposal facility (test case), with all the steps of the MEIA applied sequentially. In addition, the methodology is applied to an actual cases of waste management for hazardous wastes from the coal fuel cycle, demonstrating several possibilities for application of the MEIA from a practical perspective. The experience obtained in the development of the work shows that the use of the MEIA for the assessment of management options for hazardous and radioactive wastes gives important advantages, simplifying the execution of the assessment, its tracability and the dissemination of methodology assessment results to to other interested parties. (Author)

  15. Impact of a pneumatic tube system transport on hemostasis parameters measurement: the experiment of Cochin universitary hospital (AP-HP, Paris, France).

    Science.gov (United States)

    Calmette, Leyla; Ibrahim, Firas; Gouin, Isabelle; Horellou, Marie-Hélène; Mazoyer, Élisabeth; Fontenay, Michaela; Flaujac, Claire

    2017-02-01

    Samples transported by pneumatic tube system are submitted to forces of acceleration and deceleration which can affect laboratory parameters. At Cochin hospital, majority of samples of hemostasis, except for platelets tests, are transported by pneumatic tube system. The objective of this study was to evaluate the impact of a pneumatic tube system (PTS) transport compared to hand-delivered transport on samples and to qualify Cochin hospital PTS according to requirements of standard ISO 15189. A bibliographical study was made and showed that pneumatic tube system particularly influences platelets tests. Four citrate tubes were collected in 5 healthy volunteers in the maternity: 2 tubes were transported by PTS and 2 others were hand-delivered to the laboratory. Five coagulation tests were analyzed: prothrombine time (PT), activated partial thromboplastin time (aPTT), factor (F) V, FVIII and platelet closure time with PFA-100TM collagen/epinephrine. For each volunteer, the results obtained by PTS and by hand-delivered transport were compared with formula usually used for biological analysis retake: 2.8 x standard deviation of reproductibility variation coefficient (SH GTA 01, COFRAC). This study did not show an impact of PTS on PT, aPTT, FV and FVIII. For PFA-100TM collagen/epinephrine, we noted an impact on 2/5 volunteers. These results, in agreement with the literature, led to the conclusion that Cochin hospital PTS is in compliance to transport samples for usual coagulation tests except platelet tests. This study allowed to issue French recommendations for PTS transport of hemostasis tubes qualification available on "Groupe français d'hémostase et thrombose" Web site.

  16. Parameter Estimation

    DEFF Research Database (Denmark)

    Sales-Cruz, Mauricio; Heitzig, Martina; Cameron, Ian

    2011-01-01

    In this chapter the importance of parameter estimation in model development is illustrated through various applications related to reaction systems. In particular, rate constants in a reaction system are obtained through parameter estimation methods. These approaches often require the application...... of algebraic equations as the basis for parameter estimation.These approaches are illustrated using estimations of kinetic constants from reaction system models....

  17. Increase in homeostasis model assessment of insulin resistance (HOMA-IR) had a strong impact on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion: the Saku study.

    Science.gov (United States)

    Morimoto, Akiko; Tatsumi, Yukako; Soyano, Fumie; Miyamatsu, Naomi; Sonoda, Nao; Godai, Kayo; Ohno, Yuko; Noda, Mitsuhiko; Deura, Kijyo

    2014-01-01

    Our aim was to assess the impact of increase in homeostasis model assessment of insulin resistance (HOMA-IR) on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion (IIS). This study included 2,209 participants aged 30-69 without diabetes at baseline who underwent comprehensive medical check-ups between April 2006 and March 2007 at Saku Central Hospital. Participants were classified into eight groups according to the combination of baseline IIS status (non-IIS and IIS) and category of HOMA-IR change between the baseline and follow-up examinations (decrease, no change/small increase, moderate increase, and large increase). Type 2 diabetes was determined from fasting and 2 h post-load plasma glucose concentrations at the follow-up examination between April 2009 and March 2011. At baseline, 669 individuals (30.3%) were classified as having IIS. At follow-up, 74 individuals developed type 2 diabetes. After adjusting for confounding factors including baseline HOMA-IR values, the multivariable-adjusted odds ratios (95% confidence intervals) for type 2 diabetes in the non-IIS with a decrease (mean change in HOMA-IR: -0.47), non-IIS with a moderate increase (mean change in HOMA-IR: 0.28), non-IIS with a large increase (mean change in HOMA-IR: 0.83), IIS with a decrease (mean change in HOMA-IR: -0.36), IIS with no change/small increase (mean change in HOMA-IR: 0.08), IIS with a moderate increase (mean change in HOMA-IR: 0.27), and IIS with a large increase (mean change in HOMA-IR: 0.73) groups, relative to the non-IIS with no change/small increase (mean change in HOMA-IR: 0.08) group were 0.23 (0.04, 1.11), 1.22 (0.26, 5.72), 2.01 (0.70, 6.46), 1.37 (0.32, 4.28), 3.60 (0.83, 15.57), 5.24 (1.34, 20.52), and 7.01 (1.75, 24.18), respectively. Moderate and large increases in HOMA-IR had a strong impact on the development of type 2 diabetes among individuals with IIS in this Japanese population.

  18. Increase in homeostasis model assessment of insulin resistance (HOMA-IR had a strong impact on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion: the Saku study.

    Directory of Open Access Journals (Sweden)

    Akiko Morimoto

    Full Text Available Our aim was to assess the impact of increase in homeostasis model assessment of insulin resistance (HOMA-IR on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion (IIS. This study included 2,209 participants aged 30-69 without diabetes at baseline who underwent comprehensive medical check-ups between April 2006 and March 2007 at Saku Central Hospital. Participants were classified into eight groups according to the combination of baseline IIS status (non-IIS and IIS and category of HOMA-IR change between the baseline and follow-up examinations (decrease, no change/small increase, moderate increase, and large increase. Type 2 diabetes was determined from fasting and 2 h post-load plasma glucose concentrations at the follow-up examination between April 2009 and March 2011. At baseline, 669 individuals (30.3% were classified as having IIS. At follow-up, 74 individuals developed type 2 diabetes. After adjusting for confounding factors including baseline HOMA-IR values, the multivariable-adjusted odds ratios (95% confidence intervals for type 2 diabetes in the non-IIS with a decrease (mean change in HOMA-IR: -0.47, non-IIS with a moderate increase (mean change in HOMA-IR: 0.28, non-IIS with a large increase (mean change in HOMA-IR: 0.83, IIS with a decrease (mean change in HOMA-IR: -0.36, IIS with no change/small increase (mean change in HOMA-IR: 0.08, IIS with a moderate increase (mean change in HOMA-IR: 0.27, and IIS with a large increase (mean change in HOMA-IR: 0.73 groups, relative to the non-IIS with no change/small increase (mean change in HOMA-IR: 0.08 group were 0.23 (0.04, 1.11, 1.22 (0.26, 5.72, 2.01 (0.70, 6.46, 1.37 (0.32, 4.28, 3.60 (0.83, 15.57, 5.24 (1.34, 20.52, and 7.01 (1.75, 24.18, respectively. Moderate and large increases in HOMA-IR had a strong impact on the development of type 2 diabetes among individuals with IIS in this Japanese population.

  19. Large-scale depositional characteristics of the Ulleung Basin and its impact on electrical resistivity and Archie-parameters for gas hydrate saturation estimates

    Science.gov (United States)

    Riedel, Michael; Collett, Timothy S.; Kim, H.-S.; Bahk, J.-J.; Kim, J.-H.; Ryu, B.-J.; Kim, G.-Y.

    2013-01-01

    , velocity-based calculations, and pressure-core degassing experiments. Seismically, individual boundaries between zones were determined using a grid of regional 2D seismic data. Zoning from the Archie-analysis for sites in the south-western portion of the Ulleung Basin was also observed, but at these sites it is linked to individually stacked MTDs only and does not reflect a mineralogical occurrence of biogenic opal or hemipelagic sedimentation. The individual MTD events represent differently compacted material often associated with a strong decrease in porosity (and increase in density), warranting a separate set of empirical Archie-parameters.

  20. Clustering pesticides according to their molecular properties and their impacts by considering additional ecotoxicological parameters in the TyPol method

    Science.gov (United States)

    Traore, Harouna; Crouzet, Olivier; Mamy, Laure; Sireyjol, Christine; Rossard, Virginie; Servien, Remy; Latrille, Eric; Benoit, Pierre

    2017-04-01

    The understanding of the fate of pesticides and their environmental impacts largely relies on their molecular properties. We recently developed 'TyPol' (Typology of Pollutants), a clustering method based on statistical analyses combining several environmental endpoints (i.e. environmental parameters such as sorption coefficient, degradation half-life) and one ecotoxicological one (bioconcentration factor), and structural molecular descriptors (number of atoms in the molecule, molecular surface, dipole moment, energy of orbitals…). TyPol has been conceived on the available knowledge on QSAR of a wide diversity of organic compounds (Mamy et al., 2015). This approach also allows to focus on transformation products present in different clusters and to infer possible changes in environmental fate consecutively to different degradation processes (Servien et al., 2014; Benoit et al., 2016). The initial version of TyPol did not include any ecotoxicological parameters except the bioconcentration factor (BCF), which informs more on the transfer along the trophic chain rather than on the effects on non-target organisms. The objective was to implement the TyPol database with a data set of ecotoxicological data concerning pesticides and several aquatic and terrestrial organisms, in order to test the possibility to extend TyPol to ecotoxicological effects on various organisms. The data analysis (available literature and databases) revealed that relevant ecotoxicological endpoints for terrestrial organisms such as soil microorganisms and macroinvertebrates are lacking compared to aquatic organisms. We have added seven parameters for acute (EC50, LC50) and chronic (NOEC) toxicological effects for the following organisms: Daphnia, Algae, Lemna and Earthworm. In this new configuration, TyPol was used to classify about 45 pesticides in different behavioural and ecotoxicity clusters. The clustering results were analyzed to reveals relationships between molecular descriptors

  1. Weak and strong nonlinearities in magnetic bearings

    Czech Academy of Sciences Publication Activity Database

    Půst, Ladislav

    2004-01-01

    Roč. 39, č. 7 (2004), s. 779-795 ISSN 0094-114X R&D Projects: GA ČR GA101/00/1471; GA AV ČR IBS2076301 Institutional research plan: CEZ:AV0Z2076919 Keywords : weak nonlinearitiy * strong nonlinearity * magnetics bearings Subject RIV: BI - Acoustics Impact factor: 0.605, year: 2004

  2. Rotating compressible fluids under strong stratification

    Czech Academy of Sciences Publication Activity Database

    Feireisl, Eduard; Lu, Y.; Novotný, A.

    2014-01-01

    Roč. 19, October (2014), s. 11-18 ISSN 1468-1218 Keywords : rotating fluid * compressible Navier-Stokes * strong stratification Subject RIV: BA - General Mathematics Impact factor: 2.519, year: 2014 http://www.sciencedirect.com/science/article/pii/S1468121814000212#

  3. Impacts of operating parameters on oxidation-reduction potential and pretreatment efficacy in the pretreatment of printing and dyeing wastewater by Fenton process

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Huifang, E-mail: whfkhl@sina.com [College of Environment, Jiangsu Key Laboratory of Industrial Water-Conservation and Emission Reduction, Nanjing University of Technology, Nanjing 210009 (China); Wang, Shihe [Department of Municipal Engineering, Southeast University, Nanjing 210096 (China)

    2012-12-15

    Highlights: Black-Right-Pointing-Pointer A real printing and dyeing wastewater was pretreated by Fenton process. Black-Right-Pointing-Pointer We investigated impacts of operating parameters on ORP and pretreatment efficacy. Black-Right-Pointing-Pointer Relationship among ORP, operating parameters and treatment efficacy was established. Black-Right-Pointing-Pointer Pretreatment efficacy was in proportion to the exponent of temperature reciprocal. Black-Right-Pointing-Pointer We investigated kinetics of color and COD removal and BOD{sub 5}/COD ratio in solution. - Abstract: An experiment was conducted in a batch reactor for a real printing and dyeing wastewater pretreatment using Fenton process in this study. The results showed that original pH, hydrogen peroxide concentration and ferrous sulfate concentration affected ORP value and pretreatment efficacy greatly. Under experimental conditions, the optimal original pH was 6.61, and the optimal hydrogen peroxide and ferrous sulfate concentrations were 1.50 and 0.75 g L{sup -1}, respectively. The relationship among ORP, original pH, hydrogen peroxide concentration, ferrous sulfate concentration, and color (COD or BOD{sub 5}/COD) was established, which would be instructive in on-line monitoring and control of Fenton process using ORP. In addition, the effects of wastewater temperature and oxidation time on pretreatment efficacy were also investigated. With an increase of temperature, color and COD removal efficiencies and BOD{sub 5}/COD ratio increased, and they were in proportion to the exponent of temperature reciprocal. Similarly, color and COD removal efficiencies increased with increasing oxidation time, and both color and COD removal obeyed the first-order kinetics. The BOD{sub 5}/COD ratio could be expressed by a second-degree polynomial with respect to oxidation time, and the best biodegradability of wastewater was present at the oxidation time of 6.10 h.

  4. Prognostic impact of clinicopathologic parameters in stage II/III breast cancer treated with neoadjuvant docetaxel and doxorubicin chemotherapy: paradoxical features of the triple negative breast cancer

    Directory of Open Access Journals (Sweden)

    Kim Dong-Wan

    2007-11-01

    Full Text Available Abstract Background Prognostic factors in locally advanced breast cancer treated with neoadjuvant chemotherapy differ from those of early breast cancer. The purpose of this study was to identify the clinical significance of potential predictive and prognostic factors in breast cancer patients treated by neoadjuvant chemotherapy. Methods A total of 145 stage II and III breast cancer patients received neoadjuvant docetaxel/doxorubicin chemotherapy were enrolled in this study. We examined the clinical and biological factors (ER, PR, p53, c-erbB2, bcl-2, and Ki-67 by immunohistochemistry. We analyzed clinical outcome and their correlation with clinicopathologic parameters. Results Among the clinicopathologic parameters investigated, none of the marker was correlated with response rate (RR except triple negative phenotype. Patients with triple negative phenotype showed higher RR (83.0% in triple negative vs. 62.2% in non-triple negative, p = 0.012 and pathologic complete RR (17.0% in triple negative vs. 3.1% in non-triple negative, p = 0.005. However, relapse free survival (RFS and overall survival (OS were significantly shorter in triple negative breast cancer patients (p p = 0.021, respectively. Low histologic grade, positive hormone receptors, positive bcl-2 and low level of Ki-67 were associated with prolonged RFS. In addition, positive ER and positive bcl-2 were associated with prolonged OS. In our homogeneous patient population, initial clinical stage reflects RFS and OS more precisely than pathologic stage. In multivariate analysis, initial clinical stage was the only significant independent prognostic factor to impact on OS (hazard ratio 3.597, p = 0.044. Conclusion Several molecular markers provided useful predictive and prognostic information in stage II and III breast cancer patients treated with neoadjuvant docetaxel/doxorubicin chemotherapy. Triple negative phenotype was associated with shorter survival, even though it was associated

  5. Nucleon exchange as a mechanism for strongly damped heavy ion collisions

    International Nuclear Information System (INIS)

    Jain, A.K.; Sarma, N.

    1978-01-01

    The strongly damped collisions of two heavy ions are examined in a semi-classical model where nucleons migrating across a boundary between the nuclei are captured by the other nucleus. The density variation of nucleons is taken to be the two-parameter Fermi distribution and the Thomas-Fermi model is invoked to obtain their momentum distribution. The mass exchanged during collisions, the net mass transfer and the energy lost to internal excitation are calculated as a function of the impact parameter. The angle of deep inelastic scattering is computed by correcting the elastic scattering deflection function. (Auth.)

  6. Impact of Uncertainty Characterization of Satellite Rainfall Inputs and Model Parameters on Hydrological Data Assimilation with the Ensemble Kalman Filter for Flood Prediction

    Science.gov (United States)

    Vergara, H. J.; Kirstetter, P.; Hong, Y.; Gourley, J. J.; Wang, X.

    2013-12-01

    The Ensemble Kalman Filter (EnKF) is arguably the assimilation approach that has found the widest application in hydrologic modeling. Its relatively easy implementation and computational efficiency makes it an attractive method for research and operational purposes. However, the scientific literature featuring this approach lacks guidance on how the errors in the forecast need to be characterized so as to get the required corrections from the assimilation process. Moreover, several studies have indicated that the performance of the EnKF is 'sub-optimal' when assimilating certain hydrologic observations. Likewise, some authors have suggested that the underlying assumptions of the Kalman Filter and its dependence on linear dynamics make the EnKF unsuitable for hydrologic modeling. Such assertions are often based on ineffectiveness and poor robustness of EnKF implementations resulting from restrictive specification of error characteristics and the absence of a-priori information of error magnitudes. Therefore, understanding the capabilities and limitations of the EnKF to improve hydrologic forecasts require studying its sensitivity to the manner in which errors in the hydrologic modeling system are represented through ensembles. This study presents a methodology that explores various uncertainty representation configurations to characterize the errors in the hydrologic forecasts in a data assimilation context. The uncertainty in rainfall inputs is represented through a Generalized Additive Model for Location, Scale, and Shape (GAMLSS), which provides information about second-order statistics of quantitative precipitation estimates (QPE) error. The uncertainty in model parameters is described adding perturbations based on parameters covariance information. The method allows for the identification of rainfall and parameter perturbation combinations for which the performance of the EnKF is 'optimal' given a set of objective functions. In this process, information about

  7. Dynamic Contrast-Enhanced MRI in Head-and-Neck Cancer: The Impact of Region of Interest Selection on the Intra- and Interpatient Variability of Pharmacokinetic Parameters

    Energy Technology Data Exchange (ETDEWEB)

    Craciunescu, Oana I., E-mail: oana.craciunescu@duke.edu [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); Yoo, David S. [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); Cleland, Esi [GECAD Ghana Ltd., Acra (Ghana); Muradyan, Naira [iCAD Inc., Nashua, NH (United States); Carroll, Madeline D. [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); MacFall, James R.; Barboriak, Daniel P. [Department of Radiology, Duke University Medical Center, Durham, NC (United States); Brizel, David M. [Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States); Department of Surgery, Duke University Medical Center, Durham, NC (United States)

    2012-03-01

    Purpose: Dynamic contrast-enhanced (DCE) MRI-extracted parameters measure tumor microvascular physiology and are usually calculated from an intratumor region of interest (ROI). Optimal ROI delineation is not established. The valid clinical use of DCE-MRI requires that the variation for any given parameter measured within a tumor be less than that observed between tumors in different patients. This work evaluates the impact of tumor ROI selection on the assessment of intra- and interpatient variability. Method and Materials: Head and neck cancer patients received initial targeted therapy (TT) treatment with erlotinib and/or bevacizumab, followed by radiotherapy and concurrent cisplatin with synchronous TT. DCE-MRI data from Baseline and the end of the TT regimen (Lead-In) were analyzed to generate the vascular transfer function (K{sup trans}), the extracellular volume fraction (v{sub e}), and the initial area under the concentration time curve (iAUC{sub 1min}). Four ROI sampling strategies were used: whole tumor or lymph node (Whole), the slice containing the most enhancing voxels (SliceMax), three slices centered in SliceMax (Partial), and the 5% most enhancing contiguous voxels within SliceMax (95Max). The average coefficient of variation (aCV) was calculated to establish intrapatient variability among ROI sets and interpatient variability for each ROI type. The average ratio between each intrapatient CV and the interpatient CV was calculated (aRCV). Results: Baseline primary/nodes aRCVs for different ROIs not including 95Max were, for all three MR parameters, in the range of 0.14-0.24, with Lead-In values between 0.09 and 0.2, meaning a low intrapatient vs. interpatient variation. For 95Max, intrapatient CVs approximated interpatient CVs, meaning similar data dispersion and higher aRCVs (0.6-1.27 for baseline) and 0.54-0.95 for Lead-In. Conclusion: Distinction between different patient's primary tumors and/or nodes cannot be made using 95Max ROIs. The other

  8. Including virtual photons in strong interactions

    International Nuclear Information System (INIS)

    Rusetsky, A.

    2003-01-01

    In the perturbative field-theoretical models we investigate the inclusion of the electromagnetic interactions into the purely strong theory that describes hadronic processes. In particular, we study the convention for splitting electromagnetic and strong interactions and the ambiguity of such a splitting. The issue of the interpretation of the parameters of the low-energy effective field theory in the presence of electromagnetic interactions is addressed, as well as the scale and gauge dependence of the effective theory couplings. We hope, that the results of these studies are relevant for the electromagnetic sector of ChPT. (orig.)

  9. Universal behavior of strongly correlated Fermi systems

    Energy Technology Data Exchange (ETDEWEB)

    Shaginyan, Vasilii R [B.P. Konstantinov St. Petersburg Institute of Nuclear Physics, Russian Academy of Sciences, Gatchina, Leningrad region, Rusian Federation (Russian Federation); Amusia, M Ya [A.F. Ioffe Physico-Technical Institute, Russian Academy of Sciences, St. Petersburg (Russian Federation); Popov, Konstantin G [Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, Syktyvkar (Russian Federation)

    2007-06-30

    This review discusses the construction of a theory and the analysis of phenomena occurring in strongly correlated Fermi systems such as high-T{sub c} superconductors, heavy-fermion metals, and quasi-two-dimensional Fermi systems. It is shown that the basic properties and the universal behavior of strongly correlated Fermi systems can be described in the framework of the Fermi-condensate quantum phase transition and the well-known Landau paradigm of quasiparticles and the order parameter. The concept of fermion condensation may be fruitful in studying neutron stars, finite Fermi systems, ultra-cold gases in traps, and quark plasma. (reviews of topical problems)

  10. Universal behavior of strongly correlated Fermi systems

    International Nuclear Information System (INIS)

    Shaginyan, Vasilii R; Amusia, M Ya; Popov, Konstantin G

    2007-01-01

    This review discusses the construction of a theory and the analysis of phenomena occurring in strongly correlated Fermi systems such as high-T c superconductors, heavy-fermion metals, and quasi-two-dimensional Fermi systems. It is shown that the basic properties and the universal behavior of strongly correlated Fermi systems can be described in the framework of the Fermi-condensate quantum phase transition and the well-known Landau paradigm of quasiparticles and the order parameter. The concept of fermion condensation may be fruitful in studying neutron stars, finite Fermi systems, ultra-cold gases in traps, and quark plasma. (reviews of topical problems)

  11. A high-fat, high-protein diet attenuates the negative impact of casein-induced chronic inflammation on testicular steroidogenesis and sperm parameters in adult mice.

    Science.gov (United States)

    Zhao, Jing-Lu; Zhao, Yu-Yun; Zhu, Wei-Jie

    2017-10-01

    RNA and protein levels of the StAR and 3β-HSD in group HFPD+CS were both higher than those of in group ND+CS. These results indicated that Kunming male mice with high-fat, high-protein diet and casein injection for 8weeks can be used to establish a diet-induced obesity and chronic systemic inflammation. The sperm parameters in groups ND+CS and HFPD+SI decreased accompanied by pathological changes of testicular tissue. This resultant effect of reduced serum testosterone levels was associated with the overproduction of TNF-α and IL-10 and down-regulation of StAR and CYP11A1. Under the same casein-induced chronic inflammation condition, the mice with high-fat, high-protein diet had better testicular steroidogenesis activity and sperm parameters compared with the mice in normal diet, indicating that the mice with casein-induced inflammatory injury consuming a high-fat, high-protein diet gained weight normally, reduced serum adiponectin level and increased testosterone production by an upregulation of 3β-HSD expression. High-fat, high-protein diet attenuated the negative impact of casein-induced chronic inflammation on testicular steroidogenesis and sperm parameters. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C on the regulation of Toll-like receptors, adaptor proteins and inflammatory response

    Directory of Open Access Journals (Sweden)

    Weith Andreas

    2005-11-01

    Full Text Available Abstract Background Bacterial and viral exacerbations play a crucial role in a variety of lung diseases including COPD or asthma. Since the lung epithelium is a major source of various inflammatory mediators that affect the immune response, we analyzed the inflammatory reaction of primary lung epithelial cells to different microbial molecules that are recognized by Toll-like receptors (TLR. Methods The effects of TLR ligands on primary small airway epithelial cells were analyzed in detail with respect to cytokine, chemokine and matrix metalloproteinase secretion. In addition, the regulation of the expression of TLRs and their adaptor proteins in small airway epithelial cells was investigated. Results Our data demonstrate that poly(I:C, a synthetic analog of viral dsRNA, mediated the strongest proinflammatory effects among the tested ligands, including an increased secretion of IL-6, IL-8, TNF-α, GM-CSF, GRO-α, TARC, MCP-1, MIP-3α, RANTES, IFN-β, IP-10 and ITAC as well as an increased release of MMP-1, MMP-8, MMP-9, MMP-10 and MMP-13. Furthermore, our data show that poly(I:C as well as type-1 and type-2 cytokines have a pronounced effect on the expression of TLRs and molecules involved in TLR signaling in small airway epithelial cells. Poly(I:C induced an elevated expression of TLR1, TLR2 and TLR3 and increased the gene expression of the general TLR adaptor MyD88 and IRAK-2. Simultaneously, poly(I:C decreased the expression of TLR5, TLR6 and TOLLIP. Conclusion Poly(I:C, an analog of viral dsRNA and a TLR3 ligand, triggers a strong inflammatory response in small airway epithelial cells that is likely to contribute to viral exacerbations of pulmonary diseases like asthma or COPD. The pronounced effects of poly(I:C on the expression of Toll-like receptors and molecules involved in TLR signaling is assumed to influence the immune response of the lung epithelium to viral and bacterial infections. Likewise, the regulation of TLR expression by type

  13. Impact of model complexity and multi-scale data integration on the estimation of hydrogeological parameters in a dual-porosity aquifer

    Science.gov (United States)

    Tamayo-Mas, Elena; Bianchi, Marco; Mansour, Majdi

    2018-03-01

    This study investigates the impact of model complexity and multi-scale prior hydrogeological data on the interpretation of pumping test data in a dual-porosity aquifer (the Chalk aquifer in England, UK). In order to characterize the hydrogeological properties, different approaches ranging from a traditional analytical solution (Theis approach) to more sophisticated numerical models with automatically calibrated input parameters are applied. Comparisons of results from the different approaches show that neither traditional analytical solutions nor a numerical model assuming a homogenous and isotropic aquifer can adequately explain the observed drawdowns. A better reproduction of the observed drawdowns in all seven monitoring locations is instead achieved when medium and local-scale prior information about the vertical hydraulic conductivity (K) distribution is used to constrain the model calibration process. In particular, the integration of medium-scale vertical K variations based on flowmeter measurements lead to an improvement in the goodness-of-fit of the simulated drawdowns of about 30%. Further improvements (up to 70%) were observed when a simple upscaling approach was used to integrate small-scale K data to constrain the automatic calibration process of the numerical model. Although the analysis focuses on a specific case study, these results provide insights about the representativeness of the estimates of hydrogeological properties based on different interpretations of pumping test data, and promote the integration of multi-scale data for the characterization of heterogeneous aquifers in complex hydrogeological settings.

  14. Measurement [Gamma](Z[sup 0] [yields]b anti b)/[Gamma](Z[sup 0 ][yields]hadrons) using impact parameters and leptons

    Energy Technology Data Exchange (ETDEWEB)

    Akers, R.; Alexander, G.; Allison, J.; Anderson, K.J.; Arcelli, S.; Astbury, A.; Axen, D.; Azuelos, G.; Baines, J.T.M.; Ball, A.H.; Banks, J.; Barlow, R.J.; Barnett, S.; Bartoldus, R.; Batley, J.R.; Beaudoin, G.; Beck, A.; Beck, G.A.; Becker, J.; Beeston, C.; Behnke, T.; Bell, K.W.; Bella, G.; Bentkowski, P.; Berlich, P.; Bethke, S.; Biebel, O.; Bloodworth, I.J.; Bock, P.; Boden, B.; Bosch, H.M.; Boutemeur, M.; Breuker, H.; Bright-Thomas, P.; Brown, R.M.; Buijs, A.; Burckhart, H.J.; Burgard, C.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, D.G.; Chu, S.L.; Clarke, P.E.L.; Clayton, J.C.; Cohen, I.; Conboy, J.E.; Cooper, M.; Coupland, M.; Cuffiani, M.; Dado, S.; Dallavalle, G.M.; De Jong, S.; Del Pozo, L.A.; Deng, H.; Dieckmann, A.; Dittmar, M.; Dixit, M.S.; Do Couto e Silva, E.; Duboscq, J.E.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Dumas, D.J.P.; Elcombe, P.A.; Estabrooks, P.G.; Etzion, E.; Evans, H.G.; Fabbri, F.; Fabbro, B.; Fierro, M.; Fincke-; OPAL Collaboration

    1994-02-01

    A measurement of [Gamma]sub(b anti b)/[Gamma][sub had] triple bond [Gamma](Z[sup 0][yields]b anti b)/[Gamma] (Z[sup 0][yields]hadrons) is presented using a 'mixed tag' method involving the identification of Z[sup 0][yields]b anti b events by two different techniques. The first uses the large impact parameter of tracks emerging from the decay of b-flavoured hadrons and the second their semi-leptonic decay. The identification efficiencies are measured from the data using all possible combinations of the two tags in opposite hemispheres. The method is therefore insensitive to Monte Carlo modelling of bottom quark production and of b-flavoured hadron production and decay properties, and depends only weakly on the simulation of the detector. The data sample collected by OPAL at LEP in 1990 and 1991 is considered. The result is: [Gamma]sub(b anti b)/[Gamma][sub had]=0.218[+-]0.006(stat)[+-]0.007(syst)[+-]0.007([Gamma]sub(c anti c)/[Gamma][sub had]), where the systematic uncertainty due to the charm quark partial width has been separated from the other systematic uncertainties. Combination with previous OPAL measurements gives: [Gamma]sub(b anti b)/[Gamma][sub had]=0.220[+-]0.004(stat)[+-]0.006(syst)[+-]0.006([Gamma]sub(c anti c)/[Gamma][sub had]). (orig.)

  15. Effect of atomic parameters on L-shell X-ray production cross-sections by proton impact with energies below 1 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Miranda, J. E-mail: miranda@fisica.unam.mx; Romo-Kroeger, C.; Lugo-Licona, M

    2002-04-01

    The role of the atomic parameters involved in the calculation of L-shell X-ray production cross-sections due to the impact of protons with energies below 1 MeV is discussed. Three data sets of emission rates and two tables of fluorescence yields and Coster-Kronig probabilities are compared, based on the whole body of published experimental measurements of L X-ray lines and theoretical predictions of the ECPSSR model. It is found that one specific set of emission rates together with one specific set of fluorescence yields and Coster-Kronig factors provide the best results for X-ray lines involving L{sub 2} and L{sub 3} subshell transitions. For lines based on L{sub 1} subshell transitions, however, that set of emission rates is not the best to predict the cross-sections. It is noted, however, that more reliable measurements of Coster-Kronig probabilities are necessary, in spite of the availability of refined experimental methods.

  16. Strongly interacting photons and atoms

    International Nuclear Information System (INIS)

    Alge, W.

    1999-05-01

    This thesis contains the main results of the research topics I have pursued during the my PhD studies at the University of Innsbruck and partly in collaboration with the Institut d' Optique in Orsay, France. It is divided into three parts. The first and largest part discusses the possibility of using strong standing waves as a tool to cool and trap neutral atoms in optical cavities. This is very important in the field of nonlinear optics where several successful experiments with cold atoms in cavities have been performed recently. A discussion of the optical parametric oscillator in a regime where the nonlinearity dominates the evolution is the topic of the second part. We investigated mainly the statistical properties of the cavity output of the three interactive cavity modes. Very recently a system has been proposed which promises fantastic properties. It should exhibit a giant Kerr nonlinearity with negligible absorption thus leading to a photonic turnstile device based on cold atoms in cavity. We have shown that this model suffers from overly simplistic assumptions and developed several more comprehensive approaches to study the behavior of this system. Apart from the division into three parts of different contents the thesis is divided into publications, supplements and invisible stuff. The intention of the supplements is to reach researchers which work in related areas and provide them with more detailed information about the concepts and the numerical tools we used. It is written especially for diploma and PhD students to give them a chance to use the third part of our work which is actually the largest one. They consist of a large number of computer programs we wrote to investigate the behavior of the systems in parameter regions where no hope exists to solve the equations analytically. (author)

  17. Cosmological applications of strong gravitational lensing

    DEFF Research Database (Denmark)

    Paraficz, Danuta

    value of the energy density of the two above components, together with measuring the Hubble constant that determines the age of the Universe, is a major goal of modern astrophysics. An interesting method for estimating these parameters is strong gravitational lensing of quasars (QSOs). As shown...... by Refsdal (1964), H0, !m and !! can be measured based on the time delay ("t) between multiply lensed images of QSOs, because "t depends on H0 and on the distances to lens and source, hence!m and !!. Determination of cosmological parameters using gravitational lensing suffers from some degeneracies......, but it is based on well understood physics and unlike distance ladder methods there are no calibration issues. Moreover, it has an advantage over some of the leading methods (such as Type Ia SNe) in that it is a purely cosmological approach. In this thesis, the property of strong gravitational lensing - time...