WorldWideScience

Sample records for stripes receive v1

  1. Cortical plasticity following stripe rearing in the marsupial Monodelphis domestica: neural response properties of V1.

    Science.gov (United States)

    Dooley, James C; Donaldson, Michaela S; Krubitzer, Leah A

    2017-02-01

    The functional organization of the primary visual area (V1) and the importance of sensory experience in its normal development have been well documented in eutherian mammals. However, very few studies have investigated the response properties of V1 neurons in another large class of mammals, or whether sensory experience plays a role in shaping their response properties. Thus we reared opossums (Monodelphis domestica) in normal and vertically striped cages until they reached adulthood. They were then anesthetized using urethane, and electrophysiological techniques were used to examine neuronal responses to different orientations, spatial and temporal frequencies, and contrast levels. For normal opossums, we observed responses to the temporal and spatial characteristics of the stimulus to be similar to those described in small, nocturnal, eutherian mammals such as rats and mice; neurons in V1 responded maximally to stimuli at 0.09 cycles per degree and 2.12 cycles per second. Unlike other eutherians, but similar to other marsupials investigated, only 40% of the neurons were orientation selective. In stripe-reared animals, neurons were significantly more likely to respond to vertical stimuli at a wider range of spatial frequencies, and were more sensitive to gratings at lower contrast values compared with normal animals. These results are the first to demonstrate experience-dependent plasticity in the visual system of a marsupial species. Thus the ability of cortical neurons to alter their properties based on the dynamics of the visual environment predates the emergence of eutherian mammals and was likely present in our earliest mammalian ancestors. These results are the first description of visual response properties of the most commonly studied marsupial model organism, the short-tailed opossum (Monodelphis domestica). Further, these results are the first to demonstrate experience-dependent plasticity in the visual system of a marsupial species. Thus the ability of

  2. Cortical plasticity following stripe rearing in the marsupial Monodelphis domestica: neural response properties of V1

    Science.gov (United States)

    Dooley, James C.; Donaldson, Michaela S.

    2016-01-01

    The functional organization of the primary visual area (V1) and the importance of sensory experience in its normal development have been well documented in eutherian mammals. However, very few studies have investigated the response properties of V1 neurons in another large class of mammals, or whether sensory experience plays a role in shaping their response properties. Thus we reared opossums (Monodelphis domestica) in normal and vertically striped cages until they reached adulthood. They were then anesthetized using urethane, and electrophysiological techniques were used to examine neuronal responses to different orientations, spatial and temporal frequencies, and contrast levels. For normal opossums, we observed responses to the temporal and spatial characteristics of the stimulus to be similar to those described in small, nocturnal, eutherian mammals such as rats and mice; neurons in V1 responded maximally to stimuli at 0.09 cycles per degree and 2.12 cycles per second. Unlike other eutherians, but similar to other marsupials investigated, only 40% of the neurons were orientation selective. In stripe-reared animals, neurons were significantly more likely to respond to vertical stimuli at a wider range of spatial frequencies, and were more sensitive to gratings at lower contrast values compared with normal animals. These results are the first to demonstrate experience-dependent plasticity in the visual system of a marsupial species. Thus the ability of cortical neurons to alter their properties based on the dynamics of the visual environment predates the emergence of eutherian mammals and was likely present in our earliest mammalian ancestors. NEW & NOTEWORTHY These results are the first description of visual response properties of the most commonly studied marsupial model organism, the short-tailed opossum (Monodelphis domestica). Further, these results are the first to demonstrate experience-dependent plasticity in the visual system of a marsupial species

  3. GO JUPITER PWS EDITED EDR 10KHZ WAVEFORM RECEIVER V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set includes wideband waveform measurements from the Galileo plasma wave receiver obtained during Jupiter orbital operations. These data were obtained...

  4. GO JUPITER PWS EDITED EDR 1KHZ WAVEFORM RECEIVER V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set includes wideband waveform measurements from the Galileo plasma wave receiver obtained during Jupiter orbital operations. These data were obtained...

  5. GO JUPITER PWS EDITED EDR 80KHZ WAVEFORM RECEIVER V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set includes wideband waveform measurements from the Galileo plasma wave receiver obtained during Jupiter orbital operations. These data were obtained...

  6. GALILEO EARTH PWS EDITED EARTH 1 WAVEFORM RECEIVER V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — added ARCHIVE_STATUS, ,This data set includes wideband waveform measurements from the Galileo plasma wave receiver obtained during the first Earth encounter. These...

  7. GO E PWS EDITED EARTH 2 WAVEFORM RECEIVER V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — added ARCHIVE_STATUS, ,This data set includes wideband waveform measurements from the Galileo plasma wave receiver obtained during the second Earth encounter. These...

  8. Evaluation of rumble stripes.

    Science.gov (United States)

    2010-01-01

    The objective of this study were to: a) monitor the initial installations of rumble stripes and b) evaluate the results of rumble stripe installations. : Ten rural, two-lane road locations were selected by the Kentucky Transportation Cabinet across t...

  9. Wheat Stripe Rust

    OpenAIRE

    Pace, Mike; Israelsen, Clark; Evans, Kent; Barnhill, James

    2008-01-01

    Stripe rust, or yellow rust, is primarily a foliar fungal disease of wheat, although it can infect spike and stem tissues. If the pathogen infects the spike (head) it causes extensive quality and grain yield loss. The disease is caused by the fungus Puccinia striiformis f. sp. tritici. The fungus can only survive and reproduce on wheat. It survives from one season to the next on volunteer plants.

  10. Lighting up superconducting stripes

    Science.gov (United States)

    Ergeçen, Emre; Gedik, Nuh

    2018-02-01

    Cuprate superconductors display a plethora of complex phases as a function of temperature and carrier concentration, the understanding of which could provide clues into the mechanism of superconductivity. For example, when about one-eighth of the conduction electrons are removed from the copper oxygen planes in cuprates such as La2‑xBaxCuO4 (LBCO), the doped holes (missing electrons) organize into one-dimensional stripes (1). The bulk superconducting transition temperature (Tc) is greatly reduced, and just above Tc, electrical transport perpendicular to the planes (along the c axis) becomes resistive, but parallel to the copper oxygen planes, resistivity remains zero for a range of temperatures (2). It was proposed a decade ago (3) that this anisotropic behavior is caused by pair density waves (PDWs); superconducting Cooper pairs exist along the stripes within the planes but cannot tunnel to the adjacent layers. On page 575 of this issue, Rajasekaran et al. (4) now report detection of this state in LBCO using nonlinear reflection of high-intensity terahertz (THz) light.

  11. Exploding Stars and Stripes

    Science.gov (United States)

    2011-03-01

    The discovery of a pattern of X-ray "stripes" in the remains of an exploded star may provide the first direct evidence that a cosmic event can accelerate particles to energies a hundred times higher than achieved by the most powerful particle accelerator on Earth. This result comes from a very long observation of the Tycho supernova remnant with NASA's Chandra X-ray Observatory. It could explain how some of the extremely energetic particles bombarding the Earth, called cosmic rays, are produced. "We've seen lots of intriguing structures in supernova remnants, but we've never seen stripes before," said Kristoffer Eriksen, a postdoctoral researcher at Rutgers University who led the study. "This made us think very hard about what's happening in the blast wave of this powerful explosion." This latest study from Chandra provides support for a theory about how magnetic fields can be dramatically amplified in such blast waves. In this theory, the magnetic fields become highly tangled and the motions of the particles very turbulent near the expanding supernova shock wave at the front edge of the supernova remnant. High-energy charged particles can bounce back and forth across the shock wave repeatedly, gaining energy with each crossing. Theoretical models of the motion of the most energetic particles -- which are mostly protons -- are predicted to leave a messy network of holes and dense walls corresponding to weak and strong regions of magnetic fields, respectively. The X-ray stripes discovered by the Chandra researchers are thought to be regions where the turbulence is greater and the magnetic fields more tangled than surrounding areas, and may be the walls predicted by the theory. Electrons become trapped in these regions and emit X-rays as they spiral around the magnetic field lines. However, the regular and almost periodic pattern of the X-ray stripes was not predicted by the theory. "It was a big surprise to find such a neatly arranged set of stripes," said co

  12. The Stripe State in Cupratesa

    Directory of Open Access Journals (Sweden)

    Lee T.-K.

    2012-03-01

    Full Text Available Since the discovery of high temperature superconductors (HTS two decades ago, many anomalous properties have been reported. One of the most interesting properties is the possible existence of the stripe state consisting of one dimensional charge-density modulation coupled with some kind of spin ordering. X-ray and neutron scattering experiments and recently high resolution scanning tunneling microscopy have reported direct evidences of such a structure. In particular it has found in the La-Sr-Cu-O (LSCO family the existence of the half-doped stripe with average of half a hole in one charge modulation period below and about 1/8 hole density. These results have fueled the idea about the presence of these charge or spin density wave states competing with the superconducting phase in underdoped HTS. They may even contribute to the pairing mechanism. In this talk, we will demonstrate that the presence of these stripes is actually a natural consequence of the strongly interacting t-J model by using a variational approach which provides a good enough accuracy to address the subtle result. Furthermore we show that half-doped stripes could be stabilized in hole-doped systems if we assume a simple electron-phonon interaction to renormalize the electron mass. However we have not found any evidence to support half-doped stripes in electron-doped systems.

  13. Improving striping operations through system optimization.

    Science.gov (United States)

    2015-09-01

    Striping operations generate a significant workload for Missouri Department of Transportation (MoDOT) maintenance : operations. The requirement for each striping crew to replenish its stock of paint and other consumable items from a bulk storage : fa...

  14. Eddy current manual: v.1

    International Nuclear Information System (INIS)

    Cecco, V.S.; Van Drunen, G.; Sharp, F.L.

    1983-09-01

    This training and reference manual was assembled to provide those involved in eddy current testing with both the fundamental principles of the technique as well as the knowledge to deal with often complicated test results. A non-rigorous approach is used to simplify complex physical phenomena. Emphasis is placed on proper choice of test frequency and signal interpretation. Defect detection and diagnosis receive particular attention. Design and construction of probes are covered extensively since probes play a key role in eddy current testing. The advantages and limitations of various probe types are discussed. Electromagnetic theory, instrumentation, test methods and signal analysis are covered. Simplified derivations of probe response to test parameters are presented to develop a basic understanding of eddy current behaviour. Eddy current signals are presented on impedance plane diagrams throughout the manual since this is the most common display on modern, general purpose instruments. The use of Σphase lagΣ in signal analysis is covered in detail. To supplement theory, practical examples are presented to develop proficiency in performing inspections, and to illustrate how basic principles are applied to diagnose real signals

  15. Methylmercury degradation by Pseudomonas putida V1.

    Science.gov (United States)

    Cabral, Lucélia; Yu, Ri-Qing; Crane, Sharron; Giovanella, Patricia; Barkay, Tamar; Camargo, Flávio A O

    2016-08-01

    Environmental contamination of mercury (Hg) has caused public health concerns with focuses on the neurotoxic substance methylmercury, due to its bioaccumulation and biomagnification in food chains. The goals of the present study were to examine: (i) the transformation of methylmercury, thimerosal, phenylmercuric acetate and mercuric chloride by cultures of Pseudomonas putida V1, (ii) the presence of the genes merA and merB in P. putida V1, and (iii) the degradation pathways of methylmercury by P. putida V1. Strain V1 cultures readily degraded methylmercury, thimerosal, phenylmercury acetate, and reduced mercuric chloride into gaseous Hg(0). However, the Hg transformation in LB broth by P. putida V1 was influenced by the type of Hg compounds. The merA gene was detected in P. putida V1, on the other hand, the merB gene was not detected. The sequencing of this gene, showed high similarity (100%) to the mercuric reductase gene of other Pseudomonas spp. Furthermore, tests using radioactive (14)C-methylmercury indicated an uncommon release of (14)CO2 concomitant with the production of Hg(0). The results of the present work suggest that P. putida V1 has the potential to remove methylmercury from contaminated sites. More studies are warranted to determine the mechanism of removal of methylmercury by P. putida V1. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Invasion of the striped mollusks

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Introduced to this country only five years ago, the prolific zebra mussel has infested the Great Lakes and has already begun to move into fresh waters beyond the region. Dense populations in utility water systems have caused serious problems, reducing plant efficiency and blocking lines used for cooling and fire fighting. Experts say the striped mollusk has the potential to become the industry's worst biological problem, possibly affecting 70% of US power plants. While it appears that the invader is here to stay, EPRI and others continue to develop and refine techniques to control mussel growth

  17. GRIP HURRICANE IMAGING RADIOMETER (HIRAD) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The GRIP Hurricane Imaging Radiometer (HIRAD) V1 dataset contains measurements of brightness temperature taken at 4, 5, 6 and 6.6 GHz, as well as MERRA 2 m wind...

  18. Nuclear power plant V-1, V-2

    International Nuclear Information System (INIS)

    2000-01-01

    In this leaflet the principal scheme of the Bohunice V-1 and V-2 nuclear power plants is presented. Thermal scheme of WWER 440-type NPP (primary circuit, secondary circuit, and cooling water circuit) is described

  19. USEEIO v1.1 - Matrices

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset provides the basic building blocks for the USEEIO v1.1 model and life cycle results per $1 (2013 USD) demand for all goods and services in the model in...

  20. The STRIPES Trial - Support to Rural India's Public Education System

    Science.gov (United States)

    2010-01-01

    Background Performance of primary school students in India lags far below government expectations, and major disparity exists between rural and urban areas. The Naandi Foundation has designed and implemented a programme using community members to deliver after-school academic support for children in over 1,100 schools in five Indian states. Assessments to date suggest that it might have a substantial effect. This trial aims to evaluate the impact of this programme in villages of rural Andhra Pradesh and will compare test scores for children in three arms: a control and two intervention arms. In both intervention arms additional after-school instruction and learning materials will be offered to all eligible children and in one arm girls will also receive an additional 'kit' with a uniform and clothes. Methods/Design The trial is a cluster-randomised controlled trial conducted in conjunction with the CHAMPION trial. In the CHAMPION trial 464 villages were randomised so that half receive health interventions aiming to reduce neonatal mortality. STRIPES will be introduced in those CHAMPION villages which have a public primary school attended by at least 15 students at the time of a baseline test in 2008. 214 villages of the 464 were found to fulfil above criteria, 107 belonging to the control and 107 to the intervention arm of the CHAMPION trial. These latter 107 villages will serve as control villages in the STRIPES trial. A further randomisation will be carried out within the 107 STRIPES intervention villages allocating half to receive an additional kit for girls on the top of the instruction and learning materials. The primary outcome of the trial is a composite maths and language test score. Discussion The study is designed to measure (i) whether the educational intervention affects the exam score of children compared to the control arm, (ii) if the exam scores of girls who receive the additional kit are different from those of girls living in the other STRIPES

  1. Invasion of the striped mollusks

    Energy Technology Data Exchange (ETDEWEB)

    1991-09-01

    Introduced to this country only five years ago, the prolific zebra mussel has infested the Great Lakes and has already begun to move into fresh waters beyond the region. Dense populations in utility water systems have caused serious problems, reducing plant efficiency and blocking lines used for cooling and fire fighting. Experts say the striped mollusk has the potential to become the industry's worst biological problem, possibly affecting 70% of US power plants. While it appears that the invader is here to stay, EPRI and others continue to develop and refine techniques to control mussel growth. This article describes how the mollusk got here, reviews the problems it can cause and what is being done to mitigate the problems and control the growth and spread of the mollusk.

  2. Stock characteristics of Hudson River striped bass

    International Nuclear Information System (INIS)

    Hoff, T.B.; McLaren, J.B.; Cooper, J.C.

    1988-01-01

    Striped bass, because of their tremendous popularity both commercially and recreationally, were a principal focus of the Hudson River power plant case. Between 1976 and 1979, over 23,000 age-II and older striped bass were studied as one facet of an extensive research program on the spring population in the Hudson River. Samples were collected from the overwintering as well as the spawning portion of the striped bass population, and included immature as well as mature fish. At least 12 age-groups contributed to spawning each year. Of these 12, age-groups III, IV, and V usually were most abundant, but the percentage of the population represented by any single age-group varied as the result of fluctuations in year-class strength. Males first became sexually mature at age II and females at age IV. Fast-growing individuals within a year class tended to mature earlier. Fecundity increased with the size of fish, reaching an observed maximum of about 3 million eggs per female. Although significant annual variations in maturity and growth were detected for Hudson River striped bass, there was no evidence of a consistent change in either variable that might be associated with increasing power plant operations and a reduction in striped bass abundance. Age at maturity and age structure are the two life history components that differ the most between the Hudson River population and other striped bass populations. 36 refs., 7 tabs

  3. METEOR v1.0 - User's Guide

    International Nuclear Information System (INIS)

    Palomo, E.

    1994-01-01

    This script is a User's Guide for the software package METEOR for statistical analysis of meteorological data series. The original version of METEOR have been developed by Ph.D. Elena Palomo, CIEMAT-IER, GIMASE. It is built by linking programs and routines written in FORTRAN 77 and it adds the graphical capabilities of GNUPLOT. The shape of this toolbox was designed following the criteria of modularity, flexibility and agility criteria. All the input, output and analysis options are structured in three main menus: i) the first is aimed to evaluate the quality of the data set; ii) the second is aimed for pre-processing of the data; and iii) the third is aimed towards the statistical analyses and for creating the graphical outputs. Actually the information about METEOR is constituted by three documents written in spanish: 1) METEOR v1.0: User's guide; 2) METEOR v1.0: A usage example; 3) METEOR v1.0: Design and structure of the software package. (Author)

  4. POSTNATAL PHENOTYPE AND LOCALIZATION OF SPINAL CORD V1 DERIVED INTERNEURONS

    Science.gov (United States)

    Alvarez, Francisco J.; Jonas, Philip C.; Sapir, Tamar; Hartley, Robert; Berrocal, Maria C.; Geiman, Eric J.; Todd, Andrew J.; Goulding, Martyn

    2010-01-01

    Developmental studies identified four classes (V0, V1, V2, V3) of embryonic interneurons in the ventral spinal cord. Very little however is known about their adult phenotypes. In order to further characterize interneuron cell types in the adult, the location, neurotransmitter phenotype, calcium-buffering protein expression and axon distributions of V1-derived neurons in the mouse spinal cord was determined. In the mature (P20 and older) spinal cord, most V1-derived neurons are located in lateral LVII and in LIX, few in medial LVII and none in LVIII. Approximately 40% express calbindin and/or parvalbumin, while few express calretinin. Of seven groups of ventral interneurons identified according to calcium-buffering protein expression, two groups (1 and 4) correspond with V1-derived neurons. Group 1 are Renshaw cells and intensely express calbindin and coexpress parvalbumin and calretinin. They represent 9% of the V1 population. Group 4 express only parvalbumin and represent 27% of V1-derived neurons. V1-derived group 4 neurons receive contacts from primary sensory afferents and are therefore proprioceptive interneurons and the most ventral neurons in this group receive convergent calbindin-IR Renshaw cell inputs. This subgroup resembles Ia inhibitory interneurons (IaINs) and represents 13% of V1-derived neurons. Adult V1-interneuron axons target LIX and LVII and some enter the deep dorsal horn. V1-axons do not cross the midline. V1 derived axonal varicosities were mostly (>80%) glycinergic and a third were GABAergic. None were glutamatergic or cholinergic. In summary, V1 interneurons develop into ipsilaterally projecting, inhibitory interneurons that include Renshaw cells, Ia inhibitory interneurons and other unidentified proprioceptive interneurons. PMID:16255029

  5. METHODS OF OBTAINING LONGITUDINAL STRIPES LAYOUTS

    Directory of Open Access Journals (Sweden)

    OANA Dorina

    2014-05-01

    Full Text Available From the technological point of view it is necessary that the phase of warping to be done two or three multiple warp, which results in two or three rolls of the warp final will meet only the warping. To achieve longitudinal striped fabric spinning machines is necessary to have all tensioning mechanism dispensing rolls which requires their special construction. The homogeneity of the fabric from the point of view of the warp yarns tension must be ensured by synchronizing operation of the tensioning two cutting mechanisms of the two reels on which the wires are wound with a degree of waving and thus the fuel consumption at the different weaving. It is recommended that the design be adopted average float bonds, such that the wires can be wrapped around more than two final reels. In terms of manufacturing technology with longitudinal stripes fabrics have a more complicated and expensive technology to cross-striped fabrics for the manufacture of which technology is simplified. Cross-striped fabrics containing groups of warp threads those linked to floating average is materially different. Due to this degree of crimping of wires in the stripes with different bonds makes their contract to be different, having a direct influence on the wires consumption. The different contraction of wire weaving makes warp yarn length, contained in a linked reports are so different that it requires winding wires with different bonds also differing on the final rolls.

  6. Bioinspired Heterogeneous Structural Color Stripes from Capillaries.

    Science.gov (United States)

    Zhao, Ze; Wang, Huan; Shang, Luoran; Yu, Yunru; Fu, Fanfan; Zhao, Yuanjin; Gu, Zhongze

    2017-12-01

    As an important characteristic of many creatures, structural colors play a crucial role in the survival of organisms. Inspired by these features, an intelligent structural color material with a heterogeneous striped pattern and stimuli-responsivity by fast self-assembly of colloidal nanoparticles in capillaries with a certain diameter range are presented here. The width, spacing, color, and even combination of the structural color stripe patterns can be precisely tailored by adjusting the self-assembly parameters. Attractively, with the integration of a near-infrared (NIR) light responsive graphene hydrogel into the structural color stripe pattern, the materials are endowed with light-controlled reversible bending behavior with self-reporting color indication. It is demonstrated that the striped structural color materials can be used as NIR-light-triggered dynamic barcode labels for the anti-counterfeiting of different products. These features of the bioinspired structural color stripe pattern materials indicate their potential values for mimicking structural color organisms, which will find important applications in constructing intelligent sensors, anti-counterfeiting devices, and so on. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Guiding thermomagnetic avalanches with soft magnetic stripes

    Energy Technology Data Exchange (ETDEWEB)

    Vlasko-Vlasov, V. K.; Colauto, F.; Benseman, T.; Rosenmann, D.; Kwok, W. -K.

    2017-12-01

    We demonstrate the potential for manipulating the ultrafast dynamics of thermomagnetic flux avalanches (TMA) in superconducting films with soft magnetic stripes deposited on the film. By tuning the in-plane magnetization of the stripes, we induce lines of strong magnetic potentials for Abrikosov vortices, resulting in guided slow motion of vortices along the stripe edges and preferential bursts of TMA along the stripes. Furthermore, we show that transversely polarized stripes can reduce the TMA size by diverting magnetic flux away from the major trunk of the TMA into interstripe gaps. Our data indicate that TMAs are launched from locations with enhanced vortex entry barrier, where flux accumulation followed by accelerated vortex discharge significantly reduces the threshold of the applied field ramping speed required for the creation of TMAs. Finally, vortex-antivortex annihilation at the moving front of an expanding TMA can account for the enhanced TMA activity in the receding branches of the sample's magnetization cycle and the preferred propagation of TMAs into maximum trapped flux regions.

  8. The IAC stripe82 legacy project

    Science.gov (United States)

    Román, Javier; Fliri, Juergen; Trujillo, Ignacio

    2017-03-01

    We present new deep co-adds of data taken within Stripe 82 of the Sloan Digital Sky Survey (SDSS), especially stacked to reach the faintest surface brightness limits of this data set. Our reduction puts special emphasis on preserving the characteristics of the background (sky + diffuse light) in the input images using a non-aggressive sky subtraction strategy, resulting in an exquisite quality on extremely faint structures. The IAC Stripe 82 co-adds offer a rather unique possibility to study the low surface brightness Universe like stellar haloes and disc truncations, low surface brightness, tidal galactic interactions, extremely faint dwarf galaxies, intra-cluster light or diffuse light from galactic dust. The imaging data is publicly available at http://www.iac.es/proyecto/stripe82/.

  9. Improving striping operations through system optimization - phase 2 : final report.

    Science.gov (United States)

    2016-07-01

    Striping operations generate a significant workload for MoDOT maintenance operations. The requirement for each striping crew : to replenish its stock of paint and other consumable items from a bulk storage facility, along with the necessity to make s...

  10. Gradual reconstruction of the V-1 NPP

    International Nuclear Information System (INIS)

    Stefunko, D.; Kerak, J.; Repka, M.; Libosvar, K.; Augustin, V.; Lebruska, J.; Fagula, L.

    1998-01-01

    The background and objectives of the gradual reconstruction of the Bohunice V-1 nuclear power plant are described in detail, including the pre-design and design preparation activities, tender procedures, aims, safety analyses, and technological coverage of the project. The following systems are included in the reconstruction project: (1) safety valves and pressurizer relief line system; (2) steam generator super emergency feedwater system; (3) system of steam dump valves to the atmosphere; (4) external power supply system for plant home consumption; (5) emergency core cooling system and spray system; (6) fire prevention systems; (7) electrical systems; (8) instrumentation and control systems; (9) system of accident location in the hermetic zone; (10) hermetic zone leaktightness and integrity, filtered venting system; (11) hermetic zone strength; (12) vital technological water system; (13) ventilation and air conditioning systems; and (14) seismic strengthening of the facilities. Each of the items is described in detail. (P.A.)

  11. Probing optically silent superfluid stripes in cuprates

    Science.gov (United States)

    Rajasekaran, S.; Okamoto, J.; Mathey, L.; Fechner, M.; Thampy, V.; Gu, G. D.; Cavalleri, A.

    2018-02-01

    In many theoretical models of high-temperature superconductors, remnants of superconductivity persist to temperatures higher than the transition temperature, TC. Rajasekaran et al. used nonlinear terahertz spectroscopy to probe this region of the phase diagram of a cuprate superconductor that is well known for a stripe phase that appears for certain doping levels (see the Perspective by Ergeçen and Gedik). For a sample deep in the stripe phase, a large nonlinear signal persisted from the superconducting region up to temperatures much higher than TC. The findings suggest the formation of a peculiar spatially modulated superconducting state called the pair-density wave.

  12. DNA methylation profiles correlated to striped bass sperm fertility

    Science.gov (United States)

    Striped bass (Morone saxatilis) spermatozoa are used to fertilize in vitro the eggs of white bass (Morone chrysops) to produce the preferred hybrid for the striped bass aquaculture industry. Currently, only one source of domestic striped bass juveniles are available to growers that are not obtained ...

  13. substitution line for resistance to stripe rust

    Indian Academy of Sciences (India)

    2011-08-19

    Aug 19, 2011 ... c Indian Academy of Sciences. RESEARCH ARTICLE. Molecular cytogenetic characterization of a new wheat Secale africanum. 2R a. (2D) substitution line for resistance to stripe rust. MENGPING LEI, GUANGRONG LI, SUFEN ZHANG, CHENG LIU and ZUJUN YANG. ∗. School of Life Science and ...

  14. Breakup Behavior of a Capillary Bridge on a Hydrophobic Stripe Separating Two Hydrophilic Stripes

    Science.gov (United States)

    Hartmann, Maximilian; Hardt, Steffen

    2017-11-01

    The breakup dynamics of a capillary bridge on a hydrophobic area between two liquid filaments occupying two parallel hydrophilic stripes is studied experimentally. In addition calculations with the finite-element software Surface Evolver are performed to obtain the corresponding stable minimal surfaces. Droplets of de-ionized water are placed on substrates with alternating hydrophilic and hydrophobic stripes of different width. Their volume decreases by evaporation. This results in a droplet shaped as the letter ``H'' covering two hydrophilic stripes separated by one hydrophobic stripe. The width of the capillary bridge d(t) on the hydrophobic stripe during the breakup process is observed using a high-speed camera mounted on a bright-field microscope. The results of the experiments and the numerical studies show that the critical width dcrit, indicating the point where the capillary bridge becomes unstable, mainly depends on the width ratio of the hydrophilic and hydrophobic stripes. It is found that the time derivative of d(t) first decreases after dcrit has been reached. The final breakup dynamics then follows a t 2 / 3 scaling. We kindly acknowledge the financial support by the German Research Foundation (DFG) within the Collaborative Research Centre 1194 ``Interaction of Transport and Wetting Processes'', Project A02a.

  15. STRIPE: Remote Driving Using Limited Image Data

    Science.gov (United States)

    Kay, Jennifer S.

    1997-01-01

    Driving a vehicle, either directly or remotely, is an inherently visual task. When heavy fog limits visibility, we reduce our car's speed to a slow crawl, even along very familiar roads. In teleoperation systems, an operator's view is limited to images provided by one or more cameras mounted on the remote vehicle. Traditional methods of vehicle teleoperation require that a real time stream of images is transmitted from the vehicle camera to the operator control station, and the operator steers the vehicle accordingly. For this type of teleoperation, the transmission link between the vehicle and operator workstation must be very high bandwidth (because of the high volume of images required) and very low latency (because delayed images can cause operators to steer incorrectly). In many situations, such a high-bandwidth, low-latency communication link is unavailable or even technically impossible to provide. Supervised TeleRobotics using Incremental Polyhedral Earth geometry, or STRIPE, is a teleoperation system for a robot vehicle that allows a human operator to accurately control the remote vehicle across very low bandwidth communication links, and communication links with large delays. In STRIPE, a single image from a camera mounted on the vehicle is transmitted to the operator workstation. The operator uses a mouse to pick a series of 'waypoints' in the image that define a path that the vehicle should follow. These 2D waypoints are then transmitted back to the vehicle, where they are used to compute the appropriate steering commands while the next image is being transmitted. STRIPE requires no advance knowledge of the terrain to be traversed, and can be used by novice operators with only minimal training. STRIPE is a unique combination of computer and human control. The computer must determine the 3D world path designated by the 2D waypoints and then accurately control the vehicle over rugged terrain. The human issues involve accurate path selection, and the

  16. Crystal shapes on striped surface domains

    International Nuclear Information System (INIS)

    Valencia, Antoni

    2004-01-01

    The equilibrium shapes of a simple cubic crystal in contact with a planar chemically patterned substrate are studied theoretically using an effective interface model. The substrate is primarily made of lyophobic material and is patterned with a lyophilic (easily wettable) stripe domain. Three regimes can be distinguished for the equilibrium shapes of the crystal. The transitions between these regimes as the volume of the crystal is changed are continuous or discontinuous depending on the strength of the couplings between the crystal and the lyophilic and lyophobic surface domains. If the crystal grows through a series of states close to equilibrium, the discontinuous transitions correspond to growth instabilities. These transitions are compared with similar results that have been obtained for a volume of liquid wetting a lyophilic stripe domain

  17. The preparation of immunochromatographic stripe of methamphetamine

    International Nuclear Information System (INIS)

    Jiang Jing; Liu Yibing; Zhou Ling; Guo Weizheng

    2004-01-01

    A gold immunochromatographic assay (GICA) is developed for methamphetamine in urine. Colloidal gold is obtained by reducing the gold chloride with sodium citrate, and labeled methamphetamine monoclonal antibody. The drug or metabolite competes with the immobilized drug conjugate in the test area for the limited colloidal gold-labeled antibody complex in which the stripe is made to screen the drug abuser. This method has sensitivity of 1000 μg/L, and without cross-reaction with some drugs

  18. 3D face recognition using isogeodesic stripes.

    Science.gov (United States)

    Berretti, Stefano; Del Bimbo, Alberto; Pala, Pietro

    2010-12-01

    In this paper, we present a novel approach to 3D face matching that shows high effectiveness in distinguishing facial differences between distinct individuals from differences induced by nonneutral expressions within the same individual. The approach takes into account geometrical information of the 3D face and encodes the relevant information into a compact representation in the form of a graph. Nodes of the graph represent equal width isogeodesic facial stripes. Arcs between pairs of nodes are labeled with descriptors, referred to as 3D Weighted Walkthroughs (3DWWs), that capture the mutual relative spatial displacement between all the pairs of points of the corresponding stripes. Face partitioning into isogeodesic stripes and 3DWWs together provide an approximate representation of local morphology of faces that exhibits smooth variations for changes induced by facial expressions. The graph-based representation permits very efficient matching for face recognition and is also suited to being employed for face identification in very large data sets with the support of appropriate index structures. The method obtained the best ranking at the SHREC 2008 contest for 3D face recognition. We present an extensive comparative evaluation of the performance with the FRGC v2.0 data set and the SHREC08 data set.

  19. Classifying Variable Sources in SDSS Stripe 82

    Science.gov (United States)

    Willecke Lindberg, Christina

    2018-01-01

    SDSS (Sloan Digital Sky Survey) Stripe 82 is a well-documented and researched region of the sky that does not have all of its ~67,500 variable objects labeled. By collecting data and consulting different catalogs such as the Catalina Survey, we are able to slowly cross-match more objects and add classifications within the Stripe 82 catalog. Such matching is performed either by pairing SDSS identification numbers, or by converting and comparing the coordinates of every object within the Stripe 82 catalog to every object within the classified catalog, such as the Catalina Survey catalog. If matching is performed with converted coordinates, a follow-up check is performed to ascertain that the magnitudes of the paired objects are within a reasonable margin of error and that objects have not been mismatched. Once matches have been confirmed, the light curves of classified objects can then be used to determine features that most effectively separate the different types of variable objects in feature spaces. By classifying variable objects, we can construct a reference for subsequent large research surveys, such as LSST (the Large Synoptic Survey Telescope), that could utilize SDSS data as a training set for its own classifications.

  20. Occupational Noise Reduction in CNC Striping Process

    Science.gov (United States)

    Mahmad Khairai, Kamarulzaman; Shamime Salleh, Nurul; Razlan Yusoff, Ahmad

    2018-03-01

    Occupational noise hearing loss with high level exposure is common occupational hazards. In CNC striping process, employee that exposed to high noise level for a long time as 8-hour contributes to hearing loss, create physical and psychological stress that reduce productivity. In this paper, CNC stripping process with high level noises are measured and reduced to the permissible noise exposure. First condition is all machines shutting down and second condition when all CNC machine under operations. For both conditions, noise exposures were measured to evaluate the noise problems and sources. After improvement made, the noise exposures were measured to evaluate the effectiveness of reduction. The initial average noise level at the first condition is 95.797 dB (A). After the pneumatic system with leakage was solved, the noise reduced to 55.517 dB (A). The average noise level at the second condition is 109.340 dB (A). After six machines were gathered at one area and cover that area with plastic curtain, the noise reduced to 95.209 dB (A). In conclusion, the noise level exposure in CNC striping machine is high and exceed the permissible noise exposure can be reduced to acceptable levels. The reduction of noise level in CNC striping processes enhanced productivity in the industry.

  1. Conformational Flexibility Differentiates Naturally Occurring Bet v 1 Isoforms

    Directory of Open Access Journals (Sweden)

    Sarina Grutsch

    2017-06-01

    Full Text Available The protein Bet v 1 represents the main cause for allergic reactions to birch pollen in Europe and North America. Structurally homologous isoforms of Bet v 1 can have different properties regarding allergic sensitization and Th2 polarization, most likely due to differential susceptibility to proteolytic cleavage. Using NMR relaxation experiments and molecular dynamics simulations, we demonstrate that the initial proteolytic cleavage sites in two naturally occurring Bet v 1 isoforms, Bet v 1.0101 (Bet v 1a and Bet v 1.0102 (Bet v 1d, are conformationally flexible. Inaccessible cleavage sites in helices and strands are highly flexible on the microsecond-millisecond time scale, whereas those located in loops display faster nanosecond-microsecond flexibility. The data consistently show that Bet v 1.0102 is more flexible and conformationally heterogeneous than Bet v 1.0101. Moreover, NMR hydrogen-deuterium exchange measurements reveal that the backbone amides in Bet v 1.0102 are significantly more solvent exposed, in agreement with this isoform’s higher susceptibility to proteolytic cleavage. The differential conformational flexibility of Bet v 1 isoforms, along with the transient exposure of inaccessible sites to the protein surface, may be linked to proteolytic susceptibility, representing a potential structure-based rationale for the observed differences in Th2 polarization and allergic sensitization.

  2. Inhomogeneous Stripe Phase Revisited for Surface Superconductivity

    Science.gov (United States)

    Barzykin, Victor; Gor'kov, Lev P.

    2002-11-01

    We consider 2D surface superconductivity in high magnetic fields parallel to the surface. We demonstrate that the spin-orbit interaction at the surface changes the properties of the inhomogeneous superconducting Larkin-Ovchinnikov-Fulde-Ferrell (LOFF) state that develops above fields given by the paramagnetic criterion. Strong spin-orbit interaction significantly broadens the range of existence of the LOFF phase, which takes the form of periodic superconducting stripes running along the field direction on the surface, leading to the anisotropy of its properties. Our results provide a tool for studying surface superconductivity as a function of doping.

  3. leaf and stripe rust resistance among ethiopian grown wheat ...

    African Journals Online (AJOL)

    ADMIN

    pathogen pathotypes. These varieties and lines, therefore, may be utilized in leaf and stripe rust resistance breeding programs. Key words/phrases: Leaf rust, resistance, stripe rust, Triticum aestivum, Triticum turgidum. * Current address: University of Limpopo, School of Agricultural and Environmental Sciences, Private Bag ...

  4. Transfer of stripe rust resistance from Aegilops variabilis to bread ...

    African Journals Online (AJOL)

    In terms of area, the bread wheat producing regions of China comprise the largest area in the world that is constantly threatened by stripe rust epidemics. Consequently, it is important to exploit new adultplant resistance genes in breeding. This study reports the transfer of stripe rust resistance from Aegilops variabilis to ...

  5. Bayesian Spatiotemporal Pattern and Eco-climatological Drivers of Striped Skunk Rabies in the North Central Plains.

    Science.gov (United States)

    Raghavan, Ram K; Hanlon, Cathleen A; Goodin, Douglas G; Davis, Rolan; Moore, Michael; Moore, Susan; Anderson, Gary A

    2016-04-01

    Striped skunks are one of the most important terrestrial reservoirs of rabies virus in North America, and yet the prevalence of rabies among this host is only passively monitored and the disease among this host remains largely unmanaged. Oral vaccination campaigns have not efficiently targeted striped skunks, while periodic spillovers of striped skunk variant viruses to other animals, including some domestic animals, are routinely recorded. In this study we evaluated the spatial and spatio-temporal patterns of infection status among striped skunk cases submitted for rabies testing in the North Central Plains of US in a Bayesian hierarchical framework, and also evaluated potential eco-climatological drivers of such patterns. Two Bayesian hierarchical models were fitted to point-referenced striped skunk rabies cases [n = 656 (negative), and n = 310 (positive)] received at a leading rabies diagnostic facility between the years 2007-2013. The first model included only spatial and temporal terms and a second covariate model included additional covariates representing eco-climatic conditions within a 4 km(2) home-range area for striped skunks. The better performing covariate model indicated the presence of significant spatial and temporal trends in the dataset and identified higher amounts of land covered by low-intensity developed areas [Odds ratio (OR) = 3.41; 95% Bayesian Credible Intervals (CrI) = 2.08, 3.85], higher level of patch fragmentation (OR = 1.70; 95% CrI = 1.25, 2.89), and diurnal temperature range (OR = 0.54; 95% CrI = 0.27, 0.91) to be important drivers of striped skunk rabies incidence in the study area. Model validation statistics indicated satisfactory performance for both models; however, the covariate model fared better. The findings of this study are important in the context of rabies management among striped skunks in North America, and the relevance of physical and climatological factors as risk factors for skunk to human rabies transmission and

  6. Bayesian Spatiotemporal Pattern and Eco-climatological Drivers of Striped Skunk Rabies in the North Central Plains.

    Directory of Open Access Journals (Sweden)

    Ram K Raghavan

    2016-04-01

    Full Text Available Striped skunks are one of the most important terrestrial reservoirs of rabies virus in North America, and yet the prevalence of rabies among this host is only passively monitored and the disease among this host remains largely unmanaged. Oral vaccination campaigns have not efficiently targeted striped skunks, while periodic spillovers of striped skunk variant viruses to other animals, including some domestic animals, are routinely recorded. In this study we evaluated the spatial and spatio-temporal patterns of infection status among striped skunk cases submitted for rabies testing in the North Central Plains of US in a Bayesian hierarchical framework, and also evaluated potential eco-climatological drivers of such patterns. Two Bayesian hierarchical models were fitted to point-referenced striped skunk rabies cases [n = 656 (negative, and n = 310 (positive] received at a leading rabies diagnostic facility between the years 2007-2013. The first model included only spatial and temporal terms and a second covariate model included additional covariates representing eco-climatic conditions within a 4 km(2 home-range area for striped skunks. The better performing covariate model indicated the presence of significant spatial and temporal trends in the dataset and identified higher amounts of land covered by low-intensity developed areas [Odds ratio (OR = 3.41; 95% Bayesian Credible Intervals (CrI = 2.08, 3.85], higher level of patch fragmentation (OR = 1.70; 95% CrI = 1.25, 2.89, and diurnal temperature range (OR = 0.54; 95% CrI = 0.27, 0.91 to be important drivers of striped skunk rabies incidence in the study area. Model validation statistics indicated satisfactory performance for both models; however, the covariate model fared better. The findings of this study are important in the context of rabies management among striped skunks in North America, and the relevance of physical and climatological factors as risk factors for skunk to human rabies

  7. Structural basis for capping protein sequestration by myotrophin (V-1).

    Science.gov (United States)

    Zwolak, Adam; Fujiwara, Ikuko; Hammer, John A; Tjandra, Nico

    2010-08-13

    Capping protein (CP) is a ubiquitously expressed, heterodimeric 62-kDa protein that binds the barbed end of the actin filament with high affinity to block further filament elongation. Myotrophin (V-1) is a 13-kDa ankyrin repeat-containing protein that binds CP tightly, sequestering it in a totally inactive complex in vitro. Here, we elucidate the molecular interaction between CP and V-1 by NMR. Specifically, chemical shift mapping and intermolecular paramagnetic relaxation enhancement experiments reveal that the ankyrin loops of V-1, which are essential for V-1/CP interaction, bind the basic patch near the joint of the alpha tentacle of CP shown previously to drive most of the association of CP with and affinity for the barbed end. Consistently, site-directed mutagenesis of CP shows that V-1 and the strong electrostatic binding site for CP on the barbed end compete for this basic patch on CP. These results can explain how V-1 inactivates barbed end capping by CP and why V-1 is incapable of uncapping CP-capped actin filaments, the two signature biochemical activities of V-1.

  8. ULYSSES DUST DETECTOR SYSTEM V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — Version 1.1 =========== This data set, ULY-D-UDDS-5-DUST-V1.1, differs slightly from the data set UL-D-UDDS-5-DUST-V1.0 created and reviewed at the PDS/Small Bodies...

  9. Competing States in the t-J Model: Uniform d-Wave State versus Stripe State versus Stripe State

    NARCIS (Netherlands)

    Corboz, P.R.; Rice, T.M.; Troyer, M.

    2014-01-01

    Variational studies of the t-J model on the square lattice based on infinite projected-entangled pair states confirm an extremely close competition between a uniform d-wave superconducting state and different stripe states. The site-centered stripe with an in-phase d-wave order has an equal or only

  10. The STRIPES trial--support to rural India's public education system.

    Science.gov (United States)

    Eble, Alex; Mann, Vera; Bhakta, Preetha; Lakshminarayana, Rashmi; Frost, Chris; Elbourne, Diana; Boone, Peter

    2010-02-01

    Performance of primary school students in India lags far below government expectations, and major disparity exists between rural and urban areas. The Naandi Foundation has designed and implemented a programme using community members to deliver after-school academic support for children in over 1,100 schools in five Indian states. Assessments to date suggest that it might have a substantial effect. This trial aims to evaluate the impact of this programme in villages of rural Andhra Pradesh and will compare test scores for children in three arms: a control and two intervention arms. In both intervention arms additional after-school instruction and learning materials will be offered to all eligible children and in one arm girls will also receive an additional 'kit' with a uniform and clothes. The trial is a cluster-randomised controlled trial conducted in conjunction with the CHAMPION trial. In the CHAMPION trial 464 villages were randomised so that half receive health interventions aiming to reduce neonatal mortality. STRIPES will be introduced in those CHAMPION villages which have a public primary school attended by at least 15 students at the time of a baseline test in 2008. 214 villages of the 464 were found to fulfil above criteria, 107 belonging to the control and 107 to the intervention arm of the CHAMPION trial. These latter 107 villages will serve as control villages in the STRIPES trial. A further randomisation will be carried out within the 107 STRIPES intervention villages allocating half to receive an additional kit for girls on the top of the instruction and learning materials. The primary outcome of the trial is a composite maths and language test score. The study is designed to measure (i) whether the educational intervention affects the exam score of children compared to the control arm, (ii) if the exam scores of girls who receive the additional kit are different from those of girls living in the other STRIPES intervention arm. One of the goals of

  11. Critical assessment of the evidence for striped nanoparticles.

    Directory of Open Access Journals (Sweden)

    Julian Stirling

    Full Text Available There is now a significant body of literature which reports that stripes form in the ligand shell of suitably functionalised Au nanoparticles. This stripe morphology has been proposed to strongly affect the physicochemical and biochemical properties of the particles. We critique the published evidence for striped nanoparticles in detail, with a particular focus on the interpretation of scanning tunnelling microscopy (STM data (as this is the only technique which ostensibly provides direct evidence for the presence of stripes. Through a combination of an exhaustive re-analysis of the original data, in addition to new experimental measurements of a simple control sample comprising entirely unfunctionalised particles, we show that all of the STM evidence for striped nanoparticles published to date can instead be explained by a combination of well-known instrumental artefacts, or by issues with data acquisition/analysis protocols. We also critically re-examine the evidence for the presence of ligand stripes which has been claimed to have been found from transmission electron microscopy, nuclear magnetic resonance spectroscopy, small angle neutron scattering experiments, and computer simulations. Although these data can indeed be interpreted in terms of stripe formation, we show that the reported results can alternatively be explained as arising from a combination of instrumental artefacts and inadequate data analysis techniques.

  12. Critical assessment of the evidence for striped nanoparticles.

    Science.gov (United States)

    Stirling, Julian; Lekkas, Ioannis; Sweetman, Adam; Djuranovic, Predrag; Guo, Quanmin; Pauw, Brian; Granwehr, Josef; Lévy, Raphaël; Moriarty, Philip

    2014-01-01

    There is now a significant body of literature which reports that stripes form in the ligand shell of suitably functionalised Au nanoparticles. This stripe morphology has been proposed to strongly affect the physicochemical and biochemical properties of the particles. We critique the published evidence for striped nanoparticles in detail, with a particular focus on the interpretation of scanning tunnelling microscopy (STM) data (as this is the only technique which ostensibly provides direct evidence for the presence of stripes). Through a combination of an exhaustive re-analysis of the original data, in addition to new experimental measurements of a simple control sample comprising entirely unfunctionalised particles, we show that all of the STM evidence for striped nanoparticles published to date can instead be explained by a combination of well-known instrumental artefacts, or by issues with data acquisition/analysis protocols. We also critically re-examine the evidence for the presence of ligand stripes which has been claimed to have been found from transmission electron microscopy, nuclear magnetic resonance spectroscopy, small angle neutron scattering experiments, and computer simulations. Although these data can indeed be interpreted in terms of stripe formation, we show that the reported results can alternatively be explained as arising from a combination of instrumental artefacts and inadequate data analysis techniques.

  13. ASTEROID LIGHTCURVE DERIVED DATA REFERENCES V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This file contains the full text of the references cited by identification code in the Asteroid Lightcurve Derived Data dataset (EAR-A-5-DDR-DERIVED-LIGHTCURVE-V1.0).

  14. Metamorphosis of NPP A1, V1, V2

    International Nuclear Information System (INIS)

    Dobak, D.; Moncekova, M.

    2005-01-01

    In this book the history of construction, commissioning and exploitation of NPP A1, NPP V1 and NPP V2 in Jaslovske Bohunice is presented on documentary photos. Vicinity around of these NPPs is presented, too

  15. Regridded Harmonized World Soil Database v1.2

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: This data set describes select global soil parameters from the Harmonized World Soil Database (HWSD) v1.2, including additional calculated parameters such...

  16. Regridded Harmonized World Soil Database v1.2

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set describes select global soil parameters from the Harmonized World Soil Database (HWSD) v1.2, including additional calculated parameters such as area...

  17. Books Received

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Books Received. Articles in Resonance – Journal of Science Education. Volume 1 Issue 1 January 1996 pp 118-118 Books Received. Books Received · More Details Fulltext PDF. Volume 1 Issue 2 February 1996 pp 120-120 Books Received. Books Received.

  18. Stripe order from the perspective of the Hubbard model

    Energy Technology Data Exchange (ETDEWEB)

    Devereaux, Thomas Peter

    2018-03-01

    A microscopic understanding of the strongly correlated physics of the cuprates must account for the translational and rotational symmetry breaking that is present across all cuprate families, commonly in the form of stripes. Here we investigate emergence of stripes in the Hubbard model, a minimal model believed to be relevant to the cuprate superconductors, using determinant quantum Monte Carlo (DQMC) simulations at finite temperatures and density matrix renormalization group (DMRG) ground state calculations. By varying temperature, doping, and model parameters, we characterize the extent of stripes throughout the phase diagram of the Hubbard model. Our results show that including the often neglected next-nearest-neighbor hopping leads to the absence of spin incommensurability upon electron-doping and nearly half-filled stripes upon hole-doping. The similarities of these findings to experimental results on both electron and hole-doped cuprate families support a unified description across a large portion of the cuprate phase diagram.

  19. Curcurbita pepo subspecies delineates striped cucumber beetle (Acalymma vittatum) preference

    Science.gov (United States)

    Brzozowski, L; Leckie, B M; Gardner, J; Hoffmann, M P; Mazourek, M

    2016-01-01

    The striped cucumber beetle (Acalymma vittatum (F.)) is a destructive pest of cucurbit crops, and management could be improved by host plant resistance, especially in organic farming systems. However, despite the variation in striped cucumber beetle preference observed within the economically important species, Cucurbita pepo L., plant breeders and entomologists lacked a simple framework to classify and exploit these differences. This study used recent phylogenetic evidence and bioassays to organize striped cucumber beetle preference within C. pepo. Our results indicate preference contrasts between the two agriculturally relevant subspecies: C. pepo subsp. texana and C. pepo subsp. pepo. Plants of C. pepo subsp. pepo were more strongly preferred than C. pepo subsp. texana plants. This structure of beetle preference in C. pepo will allow plant breeders and entomologists to better focus research efforts on host plant non-preference to control striped cucumber beetles. PMID:27347423

  20. Pathological changes associated with white striping in broiler breast muscles.

    Science.gov (United States)

    Kuttappan, V A; Shivaprasad, H L; Shaw, D P; Valentine, B A; Hargis, B M; Clark, F D; McKee, S R; Owens, C M

    2013-02-01

    White striping is a condition in broiler chickens characterized grossly by the occurrence of white striations, seen parallel to the direction of muscle fibers, on broiler breast fillets and thighs. Based on visual evaluation of the intensity of white striping, breast fillets can be categorized into normal (NORM), moderate (MOD), and severe (SEV) categories. This study was undertaken to evaluate the details of changes in histology as well as proximate composition occurring in the fillets with respect to the 3 degrees of white striping. In experiment 1, representative breast fillets for each degree of white striping (n = 20) were collected from 45-d-old broilers, approximately 2 h postmortem. From each fillet, 2 skeletal muscle samples were obtained and fixed in 10% neutral buffered formalin. To identify and differentiate the histological changes, slides were prepared and stained using hematoxylin and eosin, Masson's Trichrome, and Oil Red O stains. In experiment 2, samples with 3 degrees of white striping were collected from 57-d-old birds for conducting proximate analysis. Major histopathological changes observed in the MOD and SEV samples consisted of loss of cross striations, variability in fiber size, floccular/vacuolar degeneration and lysis of fibers, mild mineralization, occasional regeneration (nuclear rowing and multinucleated cells), mononuclear cell infiltration, lipidosis, and interstitial inflammation and fibrosis. Microscopic lesions were visually scored for degeneration and necrosis, fibrosis, and lipidosis. The scale used to score the samples ranged from 0 (normal) to 3 (severe). There was an increase (P white striping increased from NORM to SEV. The results from the histopathological study were supported by the findings from proximate analysis confirming that the fat and protein contents of muscle increased (P white striping increased. In conclusion, the histopathological changes occurring in white striping indicate a degenerative myopathy that

  1. Comet P/2010 V1 as a Natural Disintegration Laboratory

    Science.gov (United States)

    Jewitt, David; Weaver, Harold A.; Mutchler, Maximilian J.; Agarwal, Jessica; Meech, Karen Jean; Li, Jing; Kleyna, Jan; Ishiguro, Masateru; Wainscoat, Richard J.; Hui, Man-To

    2016-10-01

    Discovered in outburst in 2010, Jupiter-family comet P/2010 V1 (Ikeya-Murukami) was found to be split in observations at the end of 2015. We used the Hubble Space Telescope to obtain deep images of P/2010 V1 at high angular resolution in the 2016 January to March period. The resulting data, by far the best yet obtained for any split or disrupting comet, show the astrometric, photometric and morphological evolution of about 30 fragments. We will present the first results for the velocity dispersion, photometric distribution and variability and discuss the measurements in terms of models for the breakup.

  2. Distinct functional organizations for processing different motion signals in V1, V2, and V4 of macaque.

    Science.gov (United States)

    An, Xu; Gong, Hongliang; Qian, Liling; Wang, Xiaochun; Pan, Yanxia; Zhang, Xian; Yang, Yupeng; Wang, Wei

    2012-09-26

    Motion perception is qualitatively invariant across different objects and forms, namely, the same motion information can be conveyed by many different physical carriers, and it requires the processing of motion signals consisting of direction, speed, and axis or trajectory of motion defined by a moving object. Compared with the representation of orientation, the cortical processing of these different motion signals within the early ventral visual pathway of the primate remains poorly understood. Using drifting full-field noise stimuli and intrinsic optical imaging, along with cytochrome-oxidase staining, we found that the orientation domains in macaque V1, V2, and V4 that processed orientation signals also served to process motion signals associated with the axis and speed of motion. In contrast, direction domains within the thick stripes of V2 demonstrated preferences that were independent of motion speed. The population responses encoding the orientation and motion axis could be precisely reproduced by a spatiotemporal energy model. Thus, our observation of orientation domains with dual functions in V1, V2, and V4 directly support the notion that the linear representation of the temporal series of retinotopic activations may serve as another motion processing strategy in primate ventral visual pathway, contributing directly to fine form and motion analysis. Our findings further reveal that different types of motion information are differentially processed in parallel and segregated compartments within primate early visual cortices, before these motion features are fully combined in high-tier visual areas.

  3. Millijansky radio variability in SDSS stripe 82

    Energy Technology Data Exchange (ETDEWEB)

    Hodge, J. A.; Becker, R. H. [University of California, 1 Shields Avenue, Davis, CA 95616 (United States); White, R. L. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Richards, G. T., E-mail: hodge@mpia.de [Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104 (United States)

    2013-06-01

    We report on a blind survey for extragalactic radio variability that was carried out by comparing two epochs of data from the Faint Images of the Radio Sky at Twenty centimeters survey with a third epoch from a new 1.4 GHz survey of SDSS Stripe 82. The three epochs are spaced seven years apart and have an overlapping area of 60 deg{sup 2}. We uncover 89 variable sources down to the millijansky level, 75 of which are newly identified, and we find no evidence for transient phenomena. This new sample of variable sources allows us to infer an upper limit to the mean characteristic timescale of active galactic nucleus radio variability of 14 yr. We find that only 1% of extragalactic sources have fractional variability f {sub var} > 3, while 44% of Galactic sources vary by this much. The variable sample contains a larger fraction of quasars than a comparable non-variable control sample, though the majority of the variable sources appear to be extended galaxies in the optical. This implies that either quasars are not the dominant contributor to the variability of the sample, or that the deep optical data allow us to detect the host galaxies of some low-z quasars. We use the new, higher resolution data to report on the morphology of the variable sources. Finally, we show that the fraction of sources that are variable remains constant or increases at low flux densities. This may imply that next generation radio surveys with telescopes like Australian Square Kilometer Array Pathfinder and MeerKAT will see a constant or even increasing fraction of variable sources down into the sub-millijansky regime.

  4. From stripe to slab confinement for DNA linearization in nanochannels

    Science.gov (United States)

    Cifra, Peter; Benkova, Zuzana; Namer, Pavol

    We investigate suggested advantageous analysis in the linearization experiments with macromolecules confined in a stripe-like channel using Monte Carlo simulations. The enhanced chain extension in a stripe that is due to significant excluded volume interactions between monomers in two dimensions weakens on transition to experimentally feasible slit-like channel. Based on the chain extension-confinement strength dependence and the structure factor behavior for the chain in stripe we infer the excluded volume regime typical for two-dimensional systems. On transition to the slab geometry, the advantageous chain extension decreases and the Gaussian regime is observed for not very long semiflexible chains. The evidence for pseudo-ideality in confined chains is based on indicators such as the extension curves, variation of the extension with the persistence length or the structure factor. The slab behavior is observed when the stripe (originally of monomer thickness) reaches the thickness larger than cca 10nm in the third dimension. This maximum height of the slab to retain the advantage of the stripe is very low and this have implication for DNA linearization experiments. The presented analysis, however, has a broader relevance for confined polymers. Support from Slovak R&D Agency (SRDA-0451-11) is acknowledged.

  5. Preparation for and building of V-1 nuclear power plant

    International Nuclear Information System (INIS)

    Smatlak, S.; Spirko, M.

    1981-01-01

    Some findings and problems encountered during the construction of the V-1 nuclear power plant at Jaslovske Bohunice are discussed from the point of view of the investor, mainly problems associated with project preparation and relations between suppliers and the customer. The progress of construction is described and the dates are shown of the main stages of construction and tests. The construction proceeded according to a net diagram and was controlled by the construction management and a coordination group headed by the investor. An international start-up commission was established for the start-up stage. The fields are outlined of the participation and co-operation of Soviet organizations during project preparation, supplies, assembly, start-up, and fuel supplies for the V-1 nuclear power plant. (B.S.)

  6. CRISTAL V1: Criticality package for burn up credit calculations

    International Nuclear Information System (INIS)

    Gomit, Jean-Michel; Cousinou, Patrick; Gantenbein, Francoise; Diop, Cheikh; Fernandez de Grado, Guy; Mijuin, Dominique; Grouiller, Jean-Paul; Marc, Andre; Toubon, Herve

    2003-01-01

    The first version of the CRISTAL package, created and validated as part of a joint project between IRSN, COGEMA and CEA, was delivered to users in November 1999. This fruitful cooperation between IRSN, COGEMA and CEA has been pursued until 2003 with the development and the validation of the package CRISTAL V1, whose main objectives are to improve the criticality safety studies including the Burn up Credit effect. (author)

  7. The graphical user interface for CRISTAL V1

    International Nuclear Information System (INIS)

    Heulers, L.; Courtois, G.; Fernex, F.; Gomit, J.M.; Letang, E.

    2003-01-01

    This paper deals with the new Graphical User Interface (GUI) of the CRISTAL V1 package devoted to criticality studies including burn up calculations. The aim of this GUI is to offer users a high level of user-friendliness and flexibility in the data description and the results analysis of codes of the package. The three main components of the GUI (CIGAIES, EJM and OPOSSUM) are presented. The different functionalities of the tools are explained through some applications. (author)

  8. Assessment of ICARE/CATHARE V1 Severe Accident Code

    International Nuclear Information System (INIS)

    Chatelard, Patrick; Fleurot, Joelle; Marchand, Olivier; Drai, Patrick

    2006-01-01

    The ICARE/CATHARE code system has been developed by the French 'Institut de Radioprotection et de Surete Nucleaire' (IRSN) in the last decade for the detailed evaluation of Severe Accident (SA) consequences in a primary system. It is composed of the coupling of the core degradation IRSN code ICARE2 and of the thermal-hydraulics French code CATHARE2. It has been extensively used to support the level 2 Probabilistic Safety Assessment (PSA-2) of the 900 MWe PWR. This paper presents the synthesis of the ICARE/CATHARE V1 assessment which was conducted in the frame of the 'International ICARE/CATHARE Users' Club', under the management of IRSN. The ICARE/CATHARE V1 validation matrix is composed of more than 60 experiments, distributed in few thermal-hydraulics non-regression tests (to handle the front end phase of a severe accident), numerous Separate-Effect Tests, about 30 Integral Tests covering both the early and the late degradation phases, as well as a 'circuit' experiment including hydraulics loops. Finally, the simulation of the TMI-2 accident was also added to assess the code against real conditions. This validation task was aimed at assessing the ICARE/CATHARE V1 capabilities (including the stand-alone ICARE2 V3mod1 version) and also at proposing recommendations for an optimal use of this version ('Users' Guidelines'). Thus, with a correct account for the recommended guidelines, it appeared that the last ICARE/CATHARE V1 version could be reasonably used to perform best-estimate reactor studies up to a large corium slumping into the lower head. (authors)

  9. Backfitting of the nuclear plant V1 power control system

    International Nuclear Information System (INIS)

    Karpeta, C.; Rubek, J.; Stirsky, P.

    1985-01-01

    The paper deals with some aspects of implementation of modifications into the Czechoslovak nuclear plant V1 control system as called for on the basis of experience gained during the first period of the plant operation. Brief description of the plant power control system and its main functions is given. Some deficiencies in the system performance during abnormal conditions are outlined and measures taken to overcome them are presented. (author)

  10. METEOR v1.0 - A usage example

    International Nuclear Information System (INIS)

    Palomo, E.

    1994-01-01

    This script describes a detailed example of the use of the software package METEOR for statistical analysis of meteorological data series. A real spanish meteorological data set is chosen to show the capabilities of METEOR. Output files and resultant plots provided of their interpretations are compiled in three appendixes. The original version of METEOR have been developed by Ph. D.Elena Palomo, CIEMAT-IER, GIASE. It is built by linking programs and routines written in FORTRAN 77 and it adds the graphical capabilities of GNUPLOT. The shape of this toolbox was designed following the criteria of modularity, flexibility and agility criteria. All the input, output and analysis options are structured in three main menus: i) the first is aimed to evaluate the quality of the data set; ii) the second is aimed for pre-processing of the data; and iii) the third is aimed towards the statistical analyses and for creating the graphical outputs. Actually the information about METEOR is constituted by three documents written is spanish: 1) METEOR v1.0: User's guide; 2) METEOR v1.0: A usage example; 3) METEOR v1 .0: Design and structure of the software package. (Author)

  11. A neurodynamical model of brightness induction in v1.

    Directory of Open Access Journals (Sweden)

    Olivier Penacchio

    Full Text Available Brightness induction is the modulation of the perceived intensity of an area by the luminance of surrounding areas. Recent neurophysiological evidence suggests that brightness information might be explicitly represented in V1, in contrast to the more common assumption that the striate cortex is an area mostly responsive to sensory information. Here we investigate possible neural mechanisms that offer a plausible explanation for such phenomenon. To this end, a neurodynamical model which is based on neurophysiological evidence and focuses on the part of V1 responsible for contextual influences is presented. The proposed computational model successfully accounts for well known psychophysical effects for static contexts and also for brightness induction in dynamic contexts defined by modulating the luminance of surrounding areas. This work suggests that intra-cortical interactions in V1 could, at least partially, explain brightness induction effects and reveals how a common general architecture may account for several different fundamental processes, such as visual saliency and brightness induction, which emerge early in the visual processing pathway.

  12. Roadway striping productivity data analysis for INDOT Greenfield and Crawfordsville districts.

    Science.gov (United States)

    2013-11-01

    The main objective of the SPR3650 project is to provide an accurate overview of striping operation so that INDOT finds a way to : effectively save significant investment for purchasing new striping trucks in near future without compromising roadwa...

  13. Twin InSb/GaAs quantum nano-stripes: Growth optimization and related properties

    Science.gov (United States)

    Narabadeesuphakorn, Phisut; Thainoi, Supachok; Tandaechanurat, Aniwat; Kiravittaya, Suwit; Nuntawong, Noppadon; Sopitopan, Suwat; Yordsri, Visittapong; Thanachayanont, Chanchana; Kanjanachuchai, Songphol; Ratanathammaphan, Somchai; Panyakeow, Somsak

    2018-04-01

    Growth of InSb/GaAs quantum nanostructures on GaAs substrate by using molecular beam epitaxy with low growth temperature and slow growth rate typically results in a mixture of isolated and paired nano-stripe structures, which are termed as single and twin nano-stripes, respectively. In this work, we investigate the growth conditions to maximize the number ratio between twin and single nano-stripes. The highest percentage of the twin nano-stripes of up to 59% was achieved by optimizing the substrate temperature and the nano-stripe growth rate. Transmission electron microscopy reveals the substantial size and height reduction of the buried nano-stripes. We also observed the Raman shift and photon emission from our twin nano-stripes. These twin nano-stripes are promising for spintronics and quantum computing devices.

  14. Distinguishing Patterns of Charge Order: Stripes or Checkerboards

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, J.A.

    2010-04-06

    In two dimensions, quenched disorder always rounds transitions involving the breaking of spatial symmetries so, in practice, it can often be difficult to infer what form the symmetry breaking would take in the 'ideal,' zero disorder limit. We discuss methods of data analysis which can be useful for making such inferences, and apply them to the problem of determining whether the preferred order in the cuprates is 'stripes' or 'checkerboards.' In many cases we show that the experiments clearly indicate stripe order, while in others (where the observed correlation length is short), the answer is presently uncertain.

  15. Visual acuity in the striped skunk (Mephitis mephitis).

    Science.gov (United States)

    Johnson-Ulrich, Zoe; Hoffmaster, Eric; Robeson, Audrey; Vonk, Jennifer

    2017-11-01

    The visual acuity of striped skunks (Mephitis mephitis) was tested using a 2 alternative forced-choice task with square wave gratings. Skunks were reinforced with food items for touching a ball in front of a striped stimulus when paired with a ball in front of a solid gray stimulus. Skunks demonstrated a maximum visual acuity of 0.42 cycles per degree when tested with bright outdoor illumination. This poor visual acuity may be due to their nocturnal lifestyle, lack of predation, and is consistent with their preferential use of smell and sound during foraging. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  16. Assessment of ICARE/CATHARE V1mod1 and V1 applications to full scale studies

    International Nuclear Information System (INIS)

    Chatelard, P.; Barre, F.; Mutelle, H.

    2001-01-01

    The objective initially assigned to the ICARE/CATHARE V1mod1 validation task was to draw a synthesis of the ability of the code to correctly reproduce the main physical processes occurring during severe accidents. Therefore, both the domain in which the ICARE/CATHARE V1mod1 predictions are satisfactory (good confidence level) and, conversely, the identification of the main code deficiencies have to be highlighted. After a brief recall of the validation strategy and the current status of the work, this paper summarizes the main lessons which were drawn by IPSN from the validation activity which was conducted during the last two years (in 2000-2001) in the particular framework of the Users' Club (both IPSN and several foreign partners were involved in this task, under the management of IPSN). (authors)

  17. Homoeologous Recombination of the V1r1-V1r2 Gene Cluster of Pheromone Receptors in an Allotetraploid Lineage of Teleosts

    Directory of Open Access Journals (Sweden)

    Lei Zhong

    2017-11-01

    Full Text Available In contrast to other olfactory receptor families that exhibit frequent lineage-specific expansions, the vomeronasal type 1 receptor (V1R family exhibits a canonical six-member repertoire in teleosts. V1r1 and V1r2 are present in no more than one copy in all examined teleosts, including salmons, which are ancient polyploids, implying strict evolutionary constraints. However, recent polyploids have not been examined. Here, we identified a young allotetraploid lineage of weatherfishes and investigated their V1r1-V1r2 cluster. We found a novel pattern that the parental V1r1-V1r2 clusters had recombined in the tetraploid genome and that the recombinant was nearly fixed in the tetraploid population. Subsequent analyses suggested strong selective pressure, for both a new combination of paralogs and homogeneity among gene duplicates, acting on the V1r1-V1r2 pair.

  18. METEOR v1.0 - A usage example; METEOR v1.0 - Un ejemplo de uso

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, E.

    1994-07-01

    This script describes a detailed example of the use of the software package METEOR for statistical analysis of meteorological data series. A real spanish meteorological data set is chosen to show the capabilities of METEOR. Output files and resultant plots provided of their interpretations are compiled in three appendixes. The original version of METEOR have been developed by Ph. D.Elena Palomo, CIEMAT-IER, GIASE. It is built by linking programs and routines written in FORTRAN 77 and it adds the graphical capabilities of GNUPLOT. The shape of this toolbox was designed following the criteria of modularity, flexibility and agility criteria. All the input, output and analysis options are structured in three main menus: i) the first is aimed to evaluate the quality of the data set; ii) the second is aimed for pre-processing of the data; and iii) the third is aimed towards the statistical analyses and for creating the graphical outputs. Actually the information about METEOR is constituted by three documents written is spanish: 1) METEOR v1.0: User's guide; 2) METEOR v1.0: A usage example; 3) METEOR v1 .0: Design and structure of the software package. (Author)

  19. METEOR v1.0 - User's Guide; METEOR v1.0 - Guia de Usuarios

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, E.

    1994-07-01

    This script is a User's Guide for the software package METEOR for statistical analysis of meteorological data series. The original version of METEOR have been developed by Ph.D. Elena Palomo, CIEMAT-IER, GIMASE. It is built by linking programs and routines written in FORTRAN 77 and it adds the graphical capabilities of GNUPLOT. The shape of this toolbox was designed following the criteria of modularity, flexibility and agility criteria. All the input, output and analysis options are structured in three main menus: i) the first is aimed to evaluate the quality of the data set; ii) the second is aimed for pre-processing of the data; and iii) the third is aimed towards the statistical analyses and for creating the graphical outputs. Actually the information about METEOR is constituted by three documents written in spanish: 1) METEOR v1.0: User's guide; 2) METEOR v1.0: A usage example; 3) METEOR v1.0: Design and structure of the software package. (Author)

  20. Solid state synthesis and photoluminescence of Sr3Y(PxV1−xO4)3 ...

    Indian Academy of Sciences (India)

    4, August 2012, pp. 617–621. c Indian Academy of Sciences. Solid state synthesis and photoluminescence of Sr3Y(PxV1−xO4)3: Eu. 3+ submicrocrystalline rod. XIUZHEN XIAO and BING YAN. ∗. Department of Chemistry, Tongji University, Shanghai 200092, China. MS received 9 October 2010; revised 18 January 2011.

  1. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and Management...

  2. IgE and allergen-specific immunotherapy-induced IgG4recognize similar epitopes of Bet v 1, the major allergen of birch pollen.

    Science.gov (United States)

    Groh, N; von Loetzen, C S; Subbarayal, B; Möbs, C; Vogel, L; Hoffmann, A; Fötisch, K; Koutsouridou, A; Randow, S; Völker, E; Seutter von Loetzen, A; Rösch, P; Vieths, S; Pfützner, W; Bohle, B; Schiller, D

    2017-05-01

    Allergen-specific immunotherapy (AIT) with birch pollen generates Bet v 1-specific immunoglobulin (Ig)G 4 which blocks IgE-mediated hypersensitivity mechanisms. Whether IgG 4 specific for Bet v 1a competes with IgE for identical epitopes or whether novel epitope specificities of IgG 4 antibodies are developed is under debate. We sought to analyze the epitope specificities of IgE and IgG 4 antibodies from sera of patients who received AIT. 15 sera of patients (13/15 received AIT) with Bet v 1a-specific IgE and IgG 4 were analyzed. The structural arrangements of recombinant (r)Bet v 1a and rBet v 1a _11x , modified in five potential epitopes, were analyzed by circular dichroism and nuclear magnetic resonance spectroscopy. IgE binding to Bet v 1 was assessed by ELISA and mediator release assays. Competitive binding of monoclonal antibodies specific for Bet v 1a and serum IgE/IgG 4 to rBet v 1a and serum antibody binding to a non-allergenic Bet v 1-type model protein presenting an individual epitope for IgE was analyzed in ELISA and western blot. rBet v 1a _11x had a Bet v 1a - similar secondary and tertiary structure. Monomeric dispersion of rBet v 1a _11x was concentration and buffer-dependent. Up to 1500-fold increase in the EC 50 for IgE-mediated mediator release induced by rBet v 1a _11x was determined. The reduction of IgE and IgG 4 binding to rBet v 1a _11x was comparable in 67% (10/15) of sera. Bet v 1a-specific monoclonal antibodies inhibited binding of serum IgE and IgG 4 to 66.1% and 64.9%, respectively. Serum IgE and IgG 4 bound specifically to an individual epitope presented by our model protein in 33% (5/15) of sera. Patients receiving AIT develop Bet v 1a-specific IgG 4 which competes with IgE for partly identical or largely overlapping epitopes. The similarities of epitopes for IgE and IgG 4 might stimulate the development of epitope-specific diagnostics and therapeutics. © 2016 John Wiley & Sons Ltd.

  3. Seismic re-evaluation criteria for Bohunice V1 reconstruction

    International Nuclear Information System (INIS)

    Campbell, R.; Schlund, H.; Warnken, L.

    2001-01-01

    Bohunice V1 in Slovakia is a Russian designed two unit WWER 440, Model 230 Pressurized Water Reactor. The plant was not originally designed for earthquake. Subsequent and ongoing reassessments now confirm that the seismic hazard at the site is significant. EBO, the plant owner has contracted with a consortium lead by Siemens AG (REKON) to do major reconstruction of the plant to significantly enhance its safety systems by the addition of new systems and the upgrading of existing systems. As part of the reconstruction, a complete seismic assessment and upgrading is required for existing safety relevant structures, systems and components. It is not practical to conduct this reassessment and upgrading using criteria applied to new design of nuclear power plants. Alternate criteria may be used to achieve adequate safety goals. Utilities in the U.S. have faced several seismic issues with operating NPPs and to resolve these issues, alternate criteria have been developed which are much more cost effective than use of criteria for new design. These alternate criteria incorporate the knowledge obtained from investigation of the performance of equipment in major earthquakes and include provisions for structures and passive equipment to deform beyond the yield point, yet still provide their essential function. IAEA has incorporated features of these alternate criteria into draft Technical Guidelines for application to Bohunice V1 and V2. REKON has developed plant specific criteria and procedures for the Bohunice V1 reconstruction that incorporate major features of the U.S. developed alternate criteria, comply to local codes and which envelop the draft IAEA Technical Guidelines. Included in these criteria and procedures are comprehensive walkdown screening criteria for equipment, piping, HVAC and cable raceways, analytical criteria which include inelastic energy absorption factors defined on an element basis and testing criteria which include specific guidance on interpretation

  4. Bohunice V-1. Review of safety upgrading and operating experiences

    International Nuclear Information System (INIS)

    Korec, J.; Kuschel, D.

    2000-01-01

    The Bohunice site in the Slovak Republic has two Russian-designed twin-unit nuclear power plants, one equipped with reactors of the WWER 440/230 type, the other with type WWER 440/213 reactors. Two older units (V-1) started commercial operation in late 1978 and 1980 respectively and have been supplying electricity to the national grid since that time without any events that could have degraded plant safety level. In the period prior to 1990 the utility Slovenske Elektrarne (S.E.) performed extensive modifications and upgrades to the original design of the two older units V-1 NPP. Furthermore, significant steps in safety improvement for Bohunice NPP V-1 have been made since 1990. Following the political restructuring of the former Czechoslovakia and the country's new open-door policy towards western organizations, several international expert missions were focused on evaluation of Bohunice NPP safety status level and operational reliability, particularly targeting the two older units. Based on recommendations of individual expert missions and complementary deterministic and probabilistic safety analyses performed by S.E., the Czechoslovak Nuclear Regulatory Authority issued the Resolution No. 5/91 defining 81 measures concerning further safety and reliability improvement of Bohunice V1 .A range of short-term and long-term upgrades was prioritised in terms of importance to plant safety and work to implement these measures commenced in the early nineties. During the 'Small Reconstruction' from 1991 to 1993 some of the short term upgrading measures were realized to eliminate the most serious safety deficits, thus to achieve a significant reduction in core damage frequency and a major improvement in confinement integrity. In this paper and presentation the goals of the gradual reconstruction project, basic engineering, detailed engineering and realization, last major stage of Unit 2 upgrade, as well as final stage of Unit 1 upgrade in early 2000 are presented

  5. Sequence Handling by Sequence Analysis Toolbox v1.0

    DEFF Research Database (Denmark)

    Ingrell, Christian Ravnsborg; Matthiesen, Rune; Jensen, Ole Nørregaard

    2006-01-01

    analysis toolbox v1.0 was to have a general purpose sequence analyzing tool that can import sequences obtained by high-throughput sequencing methods. The program includes algorithms for calculation or prediction of isoelectric point, hydropathicity index, transmembrane segments, and glycosylphosphatidyl......The fact that mass spectrometry have become a high-throughput method calls for bioinformatic tools for automated sequence handling and prediction. For efficient use of bioinformatic tools, it is important that these tools are integrated or interfaced with each other. The purpose of sequence...... inositol-anchored proteins....

  6. Mapping of stripe rust resistance gene in an Aegilops caudata ...

    Indian Academy of Sciences (India)

    ... rust resistance depicted a single major gene conditioning adult plant resistance (APR) with stripe rust reaction varying from TR-20MS in resistant RILs signifying the presence of some minor genes as well. Genetic association with leaf rust resistance revealed that two genes are located at a recombination distance of 13%.

  7. Anatomical studies of the gastrointestinal tract of the striped sand ...

    African Journals Online (AJOL)

    A study was carried out on the gross anatomical, morphometric features and histology of the gastrointestinal tract of the Striped Sand Snake (Psammophis sibilans). Ten snakes (five males and five females) were euthanized and dissected for the study. The gastrointestinal tract appeared as a straight tubular organ from oral ...

  8. Stripe domains and magnetoresistance in thermally deposited nickel films

    International Nuclear Information System (INIS)

    Sparks, P.D.; Stern, N.P.; Snowden, D.S.; Kappus, B.A.; Checkelsky, J.G.; Harberger, S.S.; Fusello, A.M.; Eckert, J.C.

    2004-01-01

    We report a study of the domain structure and magnetoresistance of thermally deposited nickel films. For films thicker than 17 nm, we observe striped domains with period varying with film thickness as a power law with exponent 0.21±0.02 up to 120 nm thickness. There is a negative magnetoresistance for fields out of the plane

  9. Distribution patterns of striped mullet Mugil cephalus in mangrove ...

    African Journals Online (AJOL)

    Spatial and seasonal variations in density of striped mullet Mugil cephalus were investigated in four mangrove creeks in Zanzibar, Tanzania, during a one-year cycle. Fish were collected monthly in the lower, intermediate and upper reaches of each creek using a beach-seine net. All fish collected were juveniles between 2 ...

  10. Mapping of stripe rust resistance gene in an Aegilops caudata ...

    Indian Academy of Sciences (India)

    Artificial rust epidemic was created by spraying the infector rows and experimental material with the mixture of uredinospores of Pst isolates 78S84 and 46S119. Stripe rust assessment was according to the modified Cobb's scale. (Peterson et al. 1948). The RIL population was screened at the seedling stage against leaf rust ...

  11. Monitoring quantity and quality of striped catfish pond effluent

    NARCIS (Netherlands)

    Heijden, van der P.G.M.; Poelman, M.; Bosma, R.H.; Long, N.; Son, V.M.

    2012-01-01

    The production of striped catfish and other fish species in ponds has several possible impacts on the environment, one of which is caused by the discharge of pond waste water (effluent), which is enriched with nitrogen and phosphorous compounds as result of feeding and fish faeces. To restrict the

  12. Intervertebral Disk Disease in 3 Striped Skunks (Mephitis mephitis)

    NARCIS (Netherlands)

    Krauss, M.W.; Benato, L.; McDonnell, J.; Schoemaker, N.J.; Westerhof, I.; Bronson, E.; Gielen, I.; van Caelenberg, A.; Hellebuyck, T.; Meij, B.P.; de Decker, S.

    Objective To describe diagnostic findings, surgical technique, and outcome in 3 striped skunks (Mephitis mephitis) with a history of paraparesis. Study Design Case series. Animals Skunks (n = 3) with paraparesis. Methods Neurologic examination revealed upper motor neuron disease (T2–L2) in 2 skunks

  13. Modulation of the innate immune responses in the striped ...

    African Journals Online (AJOL)

    Thus, most of the innate non-specific immune responses are inducible though they are constitutive of fish immune system exhibiting a basal level of activity even in the absence of pathogen challenge. Keywords: Aeromonas hydrophila, Experimental challenge, Innate immune response, Striped snakehead murrel ...

  14. Siim Nestor soovitab : Supreme 7aastane. White Stripes / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2005-01-01

    Kolmik Supreme tähistab oma 7. tegutsemisaastat 24. juunil Von Krahlis, kus toimub ka Krecki debüütalbumi "If You Live" (väljaandjaks ettevõte Umblu) esitlus. Detroidi blues-rock duo White Stripes esitleb oma uut albumit "Get Behind Me Satan" 29. juunil Tallinnas klubis Hollywood

  15. Mapping of stripe rust resistance gene in an Aegilops caudata ...

    Indian Academy of Sciences (India)

    Genetic mapping indicated the introgression of stripe rust resistance gene on wheat chromosome. 5DS in the region carrying leaf rust resistance gene LrAc, but as an independent introgression. Simple sequence repeat (SSR) and sequence-tagged site (STS) markers designed from the survey sequence data of 5DS ...

  16. Radiation protection in decommissioning of the NPP V1

    International Nuclear Information System (INIS)

    Svitek, J.; Kaizer, J.; Siska, J.

    2014-01-01

    What's new in decommissioning of the NPP V1? In 2014 the first stage of the decommissioning should be finished. The program of the first stage was characterized by decommissioning of the non-contaminated facilities and buildings (facilities and buildings out of the control area). However, during the first stage, two key activities were done during which radiation protection had to be especially supervised: BIDSF project - Treatment and Conditioning of Wet Historical Waste - Sludge and Sorbents in the operational tanks NPP V1 (the treatment has been the condition of the regulatory body for the ending of the first stage) and preparation of decontamination of both primary circuits NPP (without reactors). In the year 2015, the second stage of decommissioning should be started. Program for the second stage is broad and it includes fragmentation and treatment of activated parts of the primary circuits (reactors, their internal parts, shielding cassettes). Modification of the radiation protection equipment on the NPP site has been made by BIDSF projects. During the first stage, two basic projects have been done: C12 - Refurbishment of the radiation protection monitoring equipment and C-10 - Free release of decommissioning materials. The present state of monitoring systems, as the result of the aforementioned projects, and the first experiences are main part of this presentation. Another activity, which prepared basic conditions for an execution of radiation protection in the second stage of decommissioning, was the preparation of documents for the procurement of license for the second stage of decommissioning. (authors)

  17. Attention and normalization circuits in macaque V1

    Science.gov (United States)

    Sanayei, M; Herrero, J L; Distler, C; Thiele, A

    2015-01-01

    Attention affects neuronal processing and improves behavioural performance. In extrastriate visual cortex these effects have been explained by normalization models, which assume that attention influences the circuit that mediates surround suppression. While normalization models have been able to explain attentional effects, their validity has rarely been tested against alternative models. Here we investigate how attention and surround/mask stimuli affect neuronal firing rates and orientation tuning in macaque V1. Surround/mask stimuli provide an estimate to what extent V1 neurons are affected by normalization, which was compared against effects of spatial top down attention. For some attention/surround effect comparisons, the strength of attentional modulation was correlated with the strength of surround modulation, suggesting that attention and surround/mask stimulation (i.e. normalization) might use a common mechanism. To explore this in detail, we fitted multiplicative and additive models of attention to our data. In one class of models, attention contributed to normalization mechanisms, whereas in a different class of models it did not. Model selection based on Akaike's and on Bayesian information criteria demonstrated that in most cells the effects of attention were best described by models where attention did not contribute to normalization mechanisms. This demonstrates that attentional influences on neuronal responses in primary visual cortex often bypass normalization mechanisms. PMID:25757941

  18. Distinct Nature of Static and Dynamic Magnetic Stripes in Cuprate Superconductors

    Science.gov (United States)

    Jacobsen, H.; Holm, S. L.; Lǎcǎtuşu, M.-E.; Rømer, A. T.; Bertelsen, M.; Boehm, M.; Toft-Petersen, R.; Grivel, J.-C.; Emery, S. B.; Udby, L.; Wells, B. O.; Lefmann, K.

    2018-01-01

    We present detailed neutron scattering studies of the static and dynamic stripes in an optimally doped high-temperature superconductor, La2 CuO4 +y . We observe that the dynamic stripes do not disperse towards the static stripes in the limit of vanishing energy transfer. Therefore, the dynamic stripes observed in neutron scattering experiments are not the Goldstone modes associated with the broken symmetry of the simultaneously observed static stripes, and the signals originate from different domains in the sample. These observations support real-space electronic phase separation in the crystal, where the static stripes in one phase are pinned versions of the dynamic stripes in the other, having slightly different periods. Our results explain earlier observations of unusual dispersions in underdoped La2 -xSrx CuO4 (x =0.07 ) and La2 -xBax CuO4 (x =0.095 ).

  19. Distinct Nature of Static and Dynamic Magnetic Stripes in Cuprate Superconductors

    DEFF Research Database (Denmark)

    Jacobsen, H.; Holm, S. L.; Lăcătuşu, M. E.

    2018-01-01

    We present detailed neutron scattering studies of the static and dynamic stripes in an optimally doped high-Temperature superconductor, La2CuO4+y. We observe that the dynamic stripes do not disperse towards the static stripes in the limit of vanishing energy transfer. Therefore, the dynamic stripes...... observed in neutron scattering experiments are not the Goldstone modes associated with the broken symmetry of the simultaneously observed static stripes, and the signals originate from different domains in the sample. These observations support real-space electronic phase separation in the crystal, where...... the static stripes in one phase are pinned versions of the dynamic stripes in the other, having slightly different periods. Our results explain earlier observations of unusual dispersions in underdoped La2-xSrxCuO4 (x=0.07) and La2-xBaxCuO4 (x=0.095)....

  20. Books Received

    Indian Academy of Sciences (India)

    Books Received. Challenge and Thrill of Pre-College. Mathematics. V Krishnamurthy et al. New Age International. 1996, Rs.220. Mathematics for Science. S M Uppal and H M Humphreys. New Age International. 1996, Rs.17S. Physics for Engineers. M R Srinivasan. New Age Publications. 1996. Statement about ownership ...

  1. CAMEX-4 DC-8 DROPSONDE SYSTEM V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The DC-8 Dropsonde System (D8D) uses dropwinsonde and Global Positioning System (GPS) receivers to measure the atmospheric state parameters (temp, humidity,...

  2. CAMEX-3 AIRBORNE VERTICAL ATMOSPHERE PROFILING SYSTEM (AVAPS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-3 DC-8 Airborne Vertical Atmosphere Profiling System (AVAPS) uses dropwinsonde and Global Positioning System (GPS) receivers to measure the atmospheric...

  3. CASSINI S INMS TELEMETRY PACKET DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The Cassini Ion and Neutral Mass Spectrometer (INMS) Packet data set contains all telemetry packets as received from the instrument. One standard product data type...

  4. SUISEI ENERGY SPECTRUM PARTICLE MEASUREMENTS V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — A floppy was received at IHW-Lead Center through Dr. Oyama. It contained the following description: SUISEI ESP / Solar Wind Parameters T. Mukai Institute of Space...

  5. CAMEX-3 AIRBORNE VERTICAL ATMOSPHERE PROFILING SYSTEM (AVAPS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-3 DC-8 Airborne Vertical Atmosphere Profiling System (AVAPS) uses dropwindsonde and Global Positioning System (GPS) receivers to measure the atmospheric...

  6. CAMEX-4 DC-8 DROPSONDE SYSTEM V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-4 DC-8 Dropsonde System dataset was collected by the DC-8 Dropsonde System (D8D) uses dropwindsonde and Global Positioning System (GPS) receivers to...

  7. ICARE/CATHARE V1: Capabilities and applications

    International Nuclear Information System (INIS)

    Zabiego, M.; Guillard, V.; Fichot, F.; Marchand, O.; Chatelard, P.; Camous, F.; Barre, F.; Lefevre, B.

    2001-01-01

    The ICARE/CATHARE code is designed to calculate in a mechanistic way reactor core damage and primary circuit behaviour in PWRs. It is developed at the French Institute for Nuclear Protection and Safety (IPSN), as an analytical support of the in-pile experimental PHEBUS programs and for studies of reactor sequences in nuclear reactors. ICARE/CATHARE V1 includes the latest version of ICARE2 (V3Mod0) which features a comprehensive set of models for late degradation allowing to follow the materials from their early melting in the core region to their later relocation into the lower plenum. It also includes the thermal-hydraulics code CATHAREZ (V1.3L/b 1) which enables to take into account the whole primary circuit and its impact on the degradation. ICARE2 describes a set of components representing either the vessel structures (fuel and control rods, barrel, vessel, etc.) or the solid debris, or the melt, or the gas. The vessel volume is discretized on a two-dimensional cylindrical meshing. Each component is described by its volume fraction in the mesh, its composition and its temperature. The solid components also have a specific geometry: rods are represented as cylinders, debris particles as a set of spheres, etc.. Several applications have already been performed, either with the stand-alone version of ICARE2 or with the coupled ICARE/CATHARE version. An application of the coupled version to the calculation of the first two phases of the TMI2 accident is presented. It shows that the coupling enables both codes to extend their range of application towards the complete calculation of a severe accident sequence. Although the calculation could not be performed up to the late degradation phase, it proves the operability of the coupled version. The results are in good agreement with TMI data during the LOCA phase, and the core uncover and degradation phenomena are qualitatively well reproduced. An application of the stand-alone ICARE2 version, including all the late

  8. ICARE/CATHARE V1: Capabilities and applications

    Energy Technology Data Exchange (ETDEWEB)

    Zabiego, M.; Guillard, V.; Fichot, F.; Marchand, O.; Chatelard, P.; Camous, F.; Barre, F. [IPSN, CEA de Cadarache (France); Lefevre, B. [CS-SI Cadarache (France)

    2001-07-01

    The ICARE/CATHARE code is designed to calculate in a mechanistic way reactor core damage and primary circuit behaviour in PWRs. It is developed at the French Institute for Nuclear Protection and Safety (IPSN), as an analytical support of the in-pile experimental PHEBUS programs and for studies of reactor sequences in nuclear reactors. ICARE/CATHARE V1 includes the latest version of ICARE2 (V3Mod0) which features a comprehensive set of models for late degradation allowing to follow the materials from their early melting in the core region to their later relocation into the lower plenum. It also includes the thermal-hydraulics code CATHAREZ (V1.3L/b 1) which enables to take into account the whole primary circuit and its impact on the degradation. ICARE2 describes a set of components representing either the vessel structures (fuel and control rods, barrel, vessel, etc.) or the solid debris, or the melt, or the gas. The vessel volume is discretized on a two-dimensional cylindrical meshing. Each component is described by its volume fraction in the mesh, its composition and its temperature. The solid components also have a specific geometry: rods are represented as cylinders, debris particles as a set of spheres, etc.. Several applications have already been performed, either with the stand-alone version of ICARE2 or with the coupled ICARE/CATHARE version. An application of the coupled version to the calculation of the first two phases of the TMI2 accident is presented. It shows that the coupling enables both codes to extend their range of application towards the complete calculation of a severe accident sequence. Although the calculation could not be performed up to the late degradation phase, it proves the operability of the coupled version. The results are in good agreement with TMI data during the LOCA phase, and the core uncover and degradation phenomena are qualitatively well reproduced. An application of the stand-alone ICARE2 version, including all the late

  9. Safety studies of the oral rabies vaccine SAD B19 in striped skunk (Mephitis mephitis).

    Science.gov (United States)

    Vos, A; Pommerening, E; Neubert, L; Kachel, S; Neubert, A

    2002-04-01

    Safety of the modified live rabies virus vaccine, SAD B19, was studied in striped skunks (Mephitis mephitis). Seven skunks received 10(7.9) foci formatting units by direct oral administration. In four cages, a vaccinated animal was placed with a control animal, the other three vaccinated skunks were housed individually. Saliva and nasal swabs were collected 1, 2, 4, 24, 48, and 72 hr post-vaccination. From all vaccinated and control animals (n = 11) blood samples were collected 0, 28, 56, 84, and 296 days post-vaccination. Three of seven vaccinated skunks seroconverted. None of the control animals had detectable levels of rabies virus neutralizing antibodies. Also no vaccine virus was isolated from the nasal and saliva swabs collected from any animal. Thus, SAD B19 was innocuous for skunks in our study after direct oral administration at field concentration.

  10. Bulk temperature measurement in thermally striped pipe flows

    International Nuclear Information System (INIS)

    Lemure, N.; Olvera, J.R.; Ruggles, A.E.

    1995-12-01

    The hot leg flows in some Pressurized Water Reactor (PWR) designs have a temperature distribution across the pipe cross-section. This condition is often referred to as a thermally striped flow. Here, the bulk temperature measurement of pipe flows with thermal striping is explored. An experiment is conducted to examine the feasibility of using temperature measurements on the external surface of the pipe to estimate the bulk temperature of the flow. Simple mixing models are used to characterize the development of the temperature profile in the flow. Simple averaging techniques and Backward Propagating Neural Net are used to predict bulk temperature from the external temperature measurements. Accurate bulk temperatures can be predicted. However, some temperature distributions in the flow effectively mask the bulk temperature from the wall and cause significant error in the bulk temperature predicted using this technique

  11. Striped bass stocks and concentrations of polychlorinated biphenyls

    Science.gov (United States)

    Fabrizio, Mary C.; Sloan, Ronald J.; O'Brien, John F.

    1991-01-01

    Harvest restrictions on striped bass Morone saxatilis fisheries in Atlantic coastal states were relaxed in 1990, but consistent, coastwide regulations of the harvest have been difficult to implement because of the mixed-stock nature of the fisheries and the recognized contamination of Hudson River fish by polychlorinated biphenyls (PCBs). We examined PCB concentrations and stock of origin of coastal striped bass to better understand the effects of these two factors on the composition of the harvest. The probability of observing differences in PCB concentration among fish from the Hudson River stock and the 'southern' group (Chesapeake Bay and Roanoke River stocks combined) was investigated with the logit model (a linear model for analysis of categorical data). Although total PCB concentrations were highly variable among fish from the two groups, striped bass classified as Hudson River stock had a significantly greater probability of having PCB concentrations equal to or greater than 2.00 mg/kg than did fish belonging to the southern group for all age- and size-classes examined. There was a significantly greater probability of observing total PCB concentrations equal to or exceeding 2.00 mg/kg in fish that were 5, 6, and 7 or more years old, and this probability increased linearly with age. We observed similar results when we examined the effect of size on total PCB concentration. The minimum-size limit estimated to permit escapement of fish to sustain stock production is 610 mm total length. Unless total PCB concentrations decrease in striped bass, it is likely that many harvestable fish will have concentrations that exceed the tolerance limit set by the U.S. Food and Drug Administration.

  12. Charge stripes and spin correlations in copper-oxide superconductors

    OpenAIRE

    Tranquada, J. M.

    1997-01-01

    Recent neutron diffraction studies have yielded evidence that, in a particular cuprate family, holes doped into the CuO(2) planes segregate into stripes that separate antiferromagnetic domains. Here it is shown that such a picture provides a quantitatively consistent interpretation of the spin fluctuations measured by neutron scattering in La(1.85)Sr(0.15)CuO(4) and YBa(2)Cu(3)O(6+x).

  13. Disorder induced stripes in d-wave superconductors

    Science.gov (United States)

    Schmid, Markus; Loder, Florian; Kampf, Arno P.; Kopp, Thilo

    2013-07-01

    Stripe phases are observed experimentally in several copper-based high-Tc superconductors near 1/8 hole doping. However, the specific characteristics may vary depending on the degree of dopant disorder and the presence or absence of a low-temperature tetragonal phase. On the basis of a Hartree-Fock decoupling scheme for the t-J model, we discuss the diverse behavior of stripe phases. In particular, the effect of inhomogeneities is investigated in two distinctly different parameter regimes which are characterized by the strength of the interaction. We observe that small concentrations of impurities or vortices pin the unidirectional density waves, and dopant disorder is capable of stabilizing a stripe phase in parameter regimes where homogeneous phases are typically favored in clean systems. The momentum-space results exhibit universal features for all coexisting density-wave solutions, nearly unchanged even in strongly disordered systems. These coexisting solutions feature generically a full energy gap and a particle-hole asymmetry in the density of states.

  14. Survey of cardiac pathologies in captive striped skunks (Mephitis mephitis).

    Science.gov (United States)

    Benato, Livia; Wack, Allison; Cerveny, Shannon N S; Rosenthal, Steven L; Bronson, Ellen

    2014-06-01

    Cardiac disease is a common finding in small mammals but it is rarely reported in striped skunks (Mephitis mephitis). The aim of this survey was to evaluate the prevalence of cardiac disease in striped skunks and to characterize the types of cardiac disease that might be present. In April 2010, a questionnaire was sent to veterinarians in zoologic collections with membership in the International Species Inventory System. Surveys were distributed to 55 institutions in the United States, Canada, and Europe. Twenty collections with a total of 95 skunks replied to the questionnaire. Of these, five collections reported at least one skunk with cardiac conditions for a total of 11 cases. In these 11 animals, the following conditions were diagnosed: myocardial fibrosis (n = 4), myxomatous valve degeneration (n = 4), hypertrophic cardiomyopathy (n = 1), dilated cardiomyopathy (n = 1), and valvular endocarditis (n = 1). Based on these findings, cardiac diseases should be considered as part of the differential diagnosis in captive striped skunks presenting with weakness, lethargy, and decreased appetite. Cardiac ultrasound also should be considered at the time of annual health examinations to evaluate for possible cardiac conditions at an early stage.

  15. Ultrafast charge localization in a stripe-phase nickelate

    Energy Technology Data Exchange (ETDEWEB)

    Coslovich, Giacomo; Huber, Bernhard; Lee, Wei-Sheng; Sasagawa, Takao; Hussain, Zahid; Bechtel, Hans A.; Martin, Michael C.; Shen, Zhi-Xun; W. Schoenlein, Robert; A. Kaindl, Robert

    2013-08-30

    Self-organized electronically-ordered phases are a recurring feature in correlated materials, resulting in e.g. fluctuating charge stripes whose role in high-Tc superconductivity is under debate. However, the relevant cause-effect relations between real-space charge correlations and low-energy excitations remain hidden in time-averaged studies. Here, we reveal ultrafast charge localization and lattice vibrational coupling as dynamical precursors of stripe formation in the model compound La1.75Sr0.25NiO4, using ultrafast and equilibrium mid-infrared spectroscopy. The opening of a pseudogap at a crossover temperature T* far above long-range stripe formation establishes the onset of electronic localization which is accompanied by an enhanced Fano asymmetry of Ni-O stretch vibrations. Ultrafast excitation triggers a sub-picosecond dynamics exposing the synchronous modulation of electron-phonon coupling and charge localization. These results illuminate the role of localization in forming the pseudogap in nickelates, opening a path to understanding this mysterious phase in a broad class of complex oxides.

  16. NATURAL TRANSVERSE VIBRATIONS OF A PRESTRESSED ORTHOTROPIC PLATE-STRIPE

    Directory of Open Access Journals (Sweden)

    Egorychev Oleg Aleksandrovich

    2012-10-01

    Full Text Available The article represents a new outlook at the boundary-value problem of natural vibrations of a homogeneous pre-stressed orthotropic plate-stripe. In the paper, the motion equation represents a new approximate hyperbolic equation (rather than a parabolic equation used in the majority of papers covering the same problem describing the vibration of a homogeneous orthotropic plate-stripe. The proposed research is based on newly derived boundary conditions describing the pin-edge, rigid, and elastic (vertical types of fixing, as well as the boundary conditions applicable to the unfixed edge of the plate. The paper contemplates the application of the Laplace transformation and a non-standard representation of a homogeneous differential equation with fixed factors. The article proposes a detailed representation of the problem of natural vibrations of a homogeneous orthotropic plate-stripe if rigidly fixed at opposite sides; besides, the article also provides frequency equations (no conclusions describing the plate characterized by the following boundary conditions: rigid fixing at one side and pin-edge fixing at the opposite side; pin-edge fixing at one side and free (unfixed other side; rigid fixing at one side and elastic fixing at the other side. The results described in the article may be helpful if applied in the construction sector whenever flat structural elements are considered. Moreover, specialists in solid mechanics and theory of elasticity may benefit from the ideas proposed in the article.

  17. Microwave permeability of stripe patterned FeCoN thin film

    International Nuclear Information System (INIS)

    Wu, Yuping; Yang, Yong; Ma, Fusheng; Zong, Baoyu; Yang, Zhihong; Ding, Jun

    2017-01-01

    Magnetic stripe patterns are of great importance for microwave applications owing to their highly tunable microwave permeability by adjusting the geometrical dimensions. In this work, stripe patterned FeCoN films with 160 nm thickness are fabricated by using standard UV photolithography. Their microwave permeability are investigated systematically via both experiment and micromagnetic simulation. The good agreement between experimental and simulation results suggests that stripe width is crucial for the microwave magnetic properties of the stripe pattern. It is demonstrated by simulation that with increasing stripe width from 1 to 80 µm the initial permeability shows a continuous growth from about 8–322, whiles the resonance frequency drops dramatically from 18.7 to 3.1 GHz at 4 µm gap size. Smaller gap size would result in slightly increased initial permeability due to larger magnetic volume ratio, accompanied by decreased resonance frequency because of stronger magnetostatic interaction. Moreover, the experimental investigation on stripe length effect indicates that the stripe length should be kept as long as possible to achieve uniform bulk resonance mode and high permeability value. Insufficient stripe length would result in low frequency edge mode and decayed bulk mode. This study could provide valuable guidelines on the selection of proper geometry dimensions of FeCoN stripe patterns for high frequency applications. - Highlights: • This work presents a systematic study on permeability of FeCoN stripe pattern. • Geometrical parameters of the stripe pattern are systematically optimized. • Several important conclusions has been obtained. • The results offer guideline on FeCoN stripe patterns for high frequency applications.

  18. Microwave permeability of stripe patterned FeCoN thin film

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Yuping [Temasek Laboratories, National University of Singapore, 5A Engineering Drive 1, Singapore 117411 (Singapore); Yang, Yong, E-mail: tslyayo@nus.edu.sg [Temasek Laboratories, National University of Singapore, 5A Engineering Drive 1, Singapore 117411 (Singapore); Ma, Fusheng; Zong, Baoyu; Yang, Zhihong [Temasek Laboratories, National University of Singapore, 5A Engineering Drive 1, Singapore 117411 (Singapore); Ding, Jun [Department of Materials Science and Engineering, National University of Singapore, Singapore 117574 (Singapore)

    2017-03-15

    Magnetic stripe patterns are of great importance for microwave applications owing to their highly tunable microwave permeability by adjusting the geometrical dimensions. In this work, stripe patterned FeCoN films with 160 nm thickness are fabricated by using standard UV photolithography. Their microwave permeability are investigated systematically via both experiment and micromagnetic simulation. The good agreement between experimental and simulation results suggests that stripe width is crucial for the microwave magnetic properties of the stripe pattern. It is demonstrated by simulation that with increasing stripe width from 1 to 80 µm the initial permeability shows a continuous growth from about 8–322, whiles the resonance frequency drops dramatically from 18.7 to 3.1 GHz at 4 µm gap size. Smaller gap size would result in slightly increased initial permeability due to larger magnetic volume ratio, accompanied by decreased resonance frequency because of stronger magnetostatic interaction. Moreover, the experimental investigation on stripe length effect indicates that the stripe length should be kept as long as possible to achieve uniform bulk resonance mode and high permeability value. Insufficient stripe length would result in low frequency edge mode and decayed bulk mode. This study could provide valuable guidelines on the selection of proper geometry dimensions of FeCoN stripe patterns for high frequency applications. - Highlights: • This work presents a systematic study on permeability of FeCoN stripe pattern. • Geometrical parameters of the stripe pattern are systematically optimized. • Several important conclusions has been obtained. • The results offer guideline on FeCoN stripe patterns for high frequency applications.

  19. A Content Analysis Comparison between Stars and Stripes and Commercial National Newspapers

    Science.gov (United States)

    1990-01-01

    McQuail , Mass Communication Theory , (London: Sage Publications, 1983) 126. 15 He notes that some of the concerns... Communication Theory . London: SAGE Publications, 1983. " S & S Ombudsman’E Plan Draws Fire," European Stars and Stripes, 4 February 1990. "Stars and Stripes May...STRIPES AND COMMERCIAL NATIONAL NEWSPAPERS A THESIS APPROVED FOR THE DEPARTMENT OF JOURNALISM AND MASS COMMUNICATION By Shirley Rafey Bruce Hinson

  20. Relationship of Soil Properties and Sugarcane Yields to Red Stripe in Louisiana.

    Science.gov (United States)

    Johnson, Richard M; Grisham, Michael P; Warnke, Kathryn Z; Maggio, Jeri R

    2016-07-01

    Symptoms of red stripe disease caused by Acidovorax avenae subsp. avenae in Louisiana between 1985 and 2010 were limited to the leaf stripe form, which caused no apparent yield loss. During 2010, the more severe top rot form was observed, and a study was initiated to investigate the distribution of red stripe in the field and determine its effects on cane and sugar yields. Soil properties data, red stripe incidence, and sugarcane yields were all highly variable and were not randomly distributed in the field. Combined harvest data showed a negative correlation between yield components and red stripe incidence, with the strongest relationship between sucrose per metric ton and disease incidence. Red stripe incidence was positively correlated with several soil properties, including phosphorus, potassium, zinc, and calcium. Red stripe incidence also was found to increase with increasing nitrogen rate, with the greatest effects in heavy soils. Results also indicated that using red-stripe-infected cane as a seed source can significantly decrease shoot emergence, stalk population, and subsequent cane and sugar yields. These combined data suggest that red stripe disease can exhibit a highly variable rate of infection in commercial sugarcane fields and may also significantly decrease sugar yields.

  1. Microsatellite markers linked to the locus of the watermelon fruit stripe pattern.

    Science.gov (United States)

    Gama, R N C S; Santos, C A F; Dias, R C S; Alves, J C S F; Nogueira, T O

    2015-01-16

    Agronomic performance and external and internal appearance of watermelon (Citrullus lanatus) fruit are important traits that should be taken into consideration during the development of a new cultivar, as well as being the principal identification elements used by the consumer, which are based on the external appearance and quality of the fruit. Externally, the fruit can be characterized in terms of the shape, the color of the lower rind, and the presence of grooves and stripes, the stripes can be classified as clearly defined or diffuse. The objective of this study was to identify microsatellite markers linked to the stripe pattern of watermelon fruit to support watermelon improvement programs, with the selection of this characteristic in the plantlet stage. F1 and F2 populations, result of a cross between the cultivars BRS Opara (clearly defined stripes) and Pérola (diffuse stripes), were phenotyped for their fruit stripe pattern. The CTAB 2X protocol was used for DNA extraction and 116 microsatellite markers were examined in a group of F2 plants that had fruit with well-defined stripes and fruit with diffuse stripes. The microsatellite loci MCPI_05 and MCPI_16 exhibited a linkage to the stripe pattern at a distance of 1.5 and 1.8 cM, respectively, with LOD scores of 39.28 and 38.11, respectively, which were located on chromosome six of the watermelon genome. These markers can be used in marker-assisted selection in watermelon improvement programs, by various research institutions.

  2. Physical Localization of a Locus from Agropyron cristatum Conferring Resistance to Stripe Rust in Common Wheat.

    Science.gov (United States)

    Zhang, Zhi; Song, Liqiang; Han, Haiming; Zhou, Shenghui; Zhang, Jinpeng; Yang, Xinming; Li, Xiuquan; Liu, Weihua; Li, Lihui

    2017-11-13

    Stripe rust, caused by Puccinia striiformis f. sp. tritici ( Pst ), is one of the most destructive diseases of wheat ( Triticum aestivum L.) worldwide. Agropyron cristatum (L.) Gaertn. (2 n = 28, PPPP), one of the wild relatives of wheat, exhibits resistance to stripe rust. In this study, wheat- A . cristatum 6P disomic addition line 4844-12 also exhibited resistance to stripe rust. To identify the stripe rust resistance locus from A . cristatum 6P, ten translocation lines, five deletion lines and the BC₂F₂ and BC₃F₂ populations of two wheat- A . cristatum 6P whole-arm translocation lines were tested with a mixture of two races of Pst in two sites during 2015-2016 and 2016-2017, being genotyped with genomic in situ hybridization (GISH) and molecular markers. The result indicated that the locus conferring stripe rust resistance was located on the terminal 20% of 6P short arm's length. Twenty-nine 6P-specific sequence-tagged-site (STS) markers mapped on the resistance locus have been acquired, which will be helpful for the fine mapping of the stripe rust resistance locus. The stripe rust-resistant translocation lines were found to carry some favorable agronomic traits, which could facilitate their use in wheat improvement. Collectively, the stripe rust resistance locus from A . cristatum 6P could be a novel resistance source and the screened stripe rust-resistant materials will be valuable for wheat disease breeding.

  3. WE-EF-207-10: Striped Ratio Grids: A New Concept for Scatter Estimation

    Energy Technology Data Exchange (ETDEWEB)

    Hsieh, S [Stanford University, Stanford, CA (United States)

    2015-06-15

    Purpose: To propose a new method for estimating scatter in x-ray imaging. We propose the “striped ratio grid,” an anti-scatter grid with alternating stripes of high scatter rejection (attained, for example, by high grid ratio) and low scatter rejection. To minimize artifacts, stripes are oriented parallel to the direction of the ramp filter. Signal discontinuities at the boundaries between stripes provide information on local scatter content, although these discontinuities are contaminated by variation in primary radiation. Methods: We emulated a striped ratio grid by imaging phantoms with two sequential CT scans, one with and one without a conventional grid, and processed them together to mimic a striped ratio grid. Two phantoms were scanned with the emulated striped ratio grid and compared with a conventional anti-scatter grid and a fan-beam acquisition, which served as ground truth. A nonlinear image processing algorithm was developed to mitigate the problem of primary variation. Results: The emulated striped ratio grid reduced scatter more effectively than the conventional grid alone. Contrast is thereby improved in projection imaging. In CT imaging, cupping is markedly reduced. Artifacts introduced by the striped ratio grid appear to be minimal. Conclusion: Striped ratio grids could be a simple and effective evolution of conventional anti-scatter grids. Unlike several other approaches currently under investigation for scatter management, striped ratio grids require minimal computation, little new hardware (at least for systems which already use removable grids) and impose few assumptions on the nature of the object being scanned.

  4. Bi-sensory, striped representations: comparative insights from owl and platypus.

    Science.gov (United States)

    Pettigrew, John D

    2004-01-01

    Bi-sensory striped arrays are described in owl and platypus that share some similarities with the other variant of bi-sensory striped array found in primate and carnivore striate cortex: ocular dominance columns. Like ocular dominance columns, the owl and platypus striped systems each involve two different topographic arrays that are cut into parallel stripes, and interdigitated, so that higher-order neurons can integrate across both arrays. Unlike ocular dominance stripes, which have a separate array for each eye, the striped array in the middle third of the owl tectum has a separate array for each cerebral hemisphere. Binocular neurons send outputs from both hemispheres to the striped array where they are segregated into parallel stripes according to hemisphere of origin. In platypus primary somatosensory cortex (S1), the two arrays of interdigitated stripes are derived from separate sensory systems in the bill, 40,000 electroreceptors and 60,000 mechanoreceptors. The stripes in platypus S1 cortex produce bimodal electrosensory-mechanosensory neurons with specificity for the time-of-arrival difference between the two systems. This "thunder-and-lightning" system would allow the platypus to estimate the distance of the prey using time disparities generated at the bill between the earlier electrical wave and the later mechanical wave caused by the motion of benthic prey. The functional significance of parallel, striped arrays is not clear, even for the highly-studied ocular dominance system, but a general strategy is proposed here that is based on the detection of temporal disparities between the two arrays that can be used to estimate distance.

  5. Spatial distribution of Prosopis glandulosa var. torreyana in vegetation stripes of the southern Chihuahuan Desert

    Science.gov (United States)

    López-Portillo, Jorge; Montaña, Carlos

    1999-05-01

    Mosaics consisting of vegetation stripes surrounded by bare areas have been described in several arid and semiarid ecosystems. The dynamics of the system depends on the redistribution of rainwater which is preferentially stored and evapotranspired in the vegetated stripes. A process of plant `colonization' in the upslope fringe of the stripes has been described in some cases and a consequent upslope migration of the stripes has been inferred, but not confirmed in all cases quoted in the literature. In this paper, we studied the spatial distribution of mesquite ( Prosopis glandulosa var. torreyana) and the soil parameters in three vegetation stripes and their associated bare areas in the southern Chihuahuan Desert. The spatial distribution of mesquites of different sizes do not coincide with that expected under the hypothesis of an uniform upslope stripe migration, but soil data suggest that current bare areas had been vegetated some time ago. Dispersion and establishment abilities enhanced by overgrazing may explain the observed mesquite distribution, but the presence of trees with high basal diameters in any part of the stripes suggests stripe permanence at the same site and no upslope migration. These results point to the conflicting evidence on stripe migration that has been already found in other areas. The most probable scenario in our study area is that of a general long-term change of form of the stripes taking place at very variable speeds in different stripes, including the possibility that some of them remain stationary for prolonged periods, and showing different histories of colonization according to the life-history of the different species concerned. The speed and regularity of the process would show a very high temporal and spatial variability due to the interaction of climatic, geomorphologic and biotic interactions.

  6. Assessing Fishers' Support of Striped Bass Management Strategies.

    Science.gov (United States)

    Murphy, Robert D; Scyphers, Steven B; Grabowski, Jonathan H

    2015-01-01

    Incorporating the perspectives and insights of stakeholders is an essential component of ecosystem-based fisheries management, such that policy strategies should account for the diverse interests of various groups of anglers to enhance their efficacy. Here we assessed fishing stakeholders' perceptions on the management of Atlantic striped bass (Morone saxatilis) and receptiveness to potential future regulations using an online survey of recreational and commercial fishers in Massachusetts and Connecticut (USA). Our results indicate that most fishers harbored adequate to positive perceptions of current striped bass management policies when asked to grade their state's management regime. Yet, subtle differences in perceptions existed between recreational and commercial fishers, as well as across individuals with differing levels of fishing experience, resource dependency, and tournament participation. Recreational fishers in both states were generally supportive or neutral towards potential management actions including slot limits (71%) and mandated circle hooks to reduce mortality of released fish (74%), but less supportive of reduced recreational bag limits (51%). Although commercial anglers were typically less supportive of management changes than their recreational counterparts, the majority were still supportive of slot limits (54%) and mandated use of circle hooks (56%). Our study suggests that both recreational and commercial fishers are generally supportive of additional management strategies aimed at sustaining healthy striped bass populations and agree on a variety of strategies. However, both stakeholder groups were less supportive of harvest reductions, which is the most direct measure of reducing mortality available to fisheries managers. By revealing factors that influence stakeholders' support or willingness to comply with management strategies, studies such as ours can help managers identify potential stakeholder support for or conflicts that may

  7. Unfolding of Vortices into Topological Stripes in a Multiferroic Material

    Science.gov (United States)

    Wang, X.; Mostovoy, M.; Han, M. G.; Horibe, Y.; Aoki, T.; Zhu, Y.; Cheong, S.-W.

    2014-06-01

    Multiferroic hexagonal RMnO3 (R =rare earths) crystals exhibit dense networks of vortex lines at which six domain walls merge. While the domain walls can be readily moved with an applied electric field, the vortex cores so far have been impossible to control. Our experiments demonstrate that shear strain induces a Magnus-type force pulling vortices and antivortices in opposite directions and unfolding them into a topological stripe domain state. We discuss the analogy between this effect and the current-driven dynamics of vortices in superconductors and superfluids.

  8. MEDIASTINAL LYMPHOMA AND CHYLOTHORAX IN A STRIPED SKUNK (MEPHITIS MEPHITIS).

    Science.gov (United States)

    Liptovszky, Mátyás; Kerekes, Zoltán; Perge, Edina; Vajdovich, Péter; Papp, Endre Ákos; Molnár, Viktor

    2017-06-01

    Tumors are infrequently reported in skunks, with only a few case reports published in the literature. Chylothorax associated with mediastinal lymphoma was diagnosed in a captive 7-yr-old male striped skunk ( Mephitis mephitis ). The animal presented with anorexia and apathy. Supportive care and prednisolone improved the animal's clinical status for 2 wk preceding its death. Histopathology supported the clinical findings, and the tumor was classified as a mediastinal non-Hodgkin lymphoma, stage 2b, which has not been documented in the literature.

  9. Response to "Critical Assessment of the Evidence for Striped Nanoparticles".

    Directory of Open Access Journals (Sweden)

    Quy Khac Ong

    Full Text Available Stirling et al., (10.1371/journal.pone.0108482 presented an analysis on some of our publications on the formation of stripe-like domains on mixed-ligand coated gold nanoparticles. The authors shed doubts on some of our results however no valid argument is provided against what we have shown since our first publication: scanning tunneling microscopy (STM images of striped nanoparticles show stripe-like domains that are independent of imaging parameters and in particular of imaging speed. We have consistently ruled out the presence of artifacts by comparing sets of images acquired at different tip speeds, finding invariance of the stipe-like domains. Stirling and co-workers incorrectly analyzed this key control, using a different microscope and imaging conditions that do not compare to ours. We show here data proving that our approach is rigorous. Furthermore, we never solely relied on image analysis to draw our conclusions; we have always used the chemical nature of the particles to assess the veracity of our images. Stirling et al. do not provide any justification for the spacing of the features that we find on nanoparticles: ~1 nm for mixed ligand particles and ~ 0.5 nm for homoligand particles. Hence our two central arguments remain unmodified: independence from imaging parameters and dependence on ligand shell chemical composition. The paper report observations on our STM images; none is a sufficient condition to prove that our images are artifacts. We thoroughly addressed issues related to STM artifacts throughout our microscopy work. Stirling et al. provide guidelines for what they consider good STM images of nanoparticles, such images are indeed present in our literature. They conclude that the evidences we provided to date are insufficient, this is a departure from one of the authors' previous article which concluded that our images were composed of artifacts. Given that four independent laboratories have reproduced our measurements and

  10. Behavior and Body Patterns of the Larger Pacific Striped Octopus.

    Directory of Open Access Journals (Sweden)

    Roy L Caldwell

    Full Text Available Over thirty years ago anecdotal accounts of the undescribed Larger Pacific Striped Octopus suggested behaviors previously unknown for octopuses. Beak-to-beak mating, dens shared by mating pairs, inking during mating and extended spawning were mentioned in publications, and enticed generations of cephalopod biologists. In 2012-2014 we were able to obtain several live specimens of this species, which remains without a formal description. All of the unique behaviors listed above were observed for animals in aquaria and are discussed here. We describe the behavior, body color patterns, and postures of 24 adults maintained in captivity. Chromatophore patterns of hatchlings are also shown.

  11. Behavior and Body Patterns of the Larger Pacific Striped Octopus.

    Science.gov (United States)

    Caldwell, Roy L; Ross, Richard; Rodaniche, Arcadio; Huffard, Christine L

    2015-01-01

    Over thirty years ago anecdotal accounts of the undescribed Larger Pacific Striped Octopus suggested behaviors previously unknown for octopuses. Beak-to-beak mating, dens shared by mating pairs, inking during mating and extended spawning were mentioned in publications, and enticed generations of cephalopod biologists. In 2012-2014 we were able to obtain several live specimens of this species, which remains without a formal description. All of the unique behaviors listed above were observed for animals in aquaria and are discussed here. We describe the behavior, body color patterns, and postures of 24 adults maintained in captivity. Chromatophore patterns of hatchlings are also shown.

  12. Vasopressin receptors V1a and V2 are not osmosensors

    DEFF Research Database (Denmark)

    Pedersen, Kasper Lykke; Assentoft, Mette; Fenton, Robert A

    2015-01-01

    Herein, we investigated whether G protein-coupled signaling via the vasopressin receptors of the V1a and V2 subtypes (V1aR and V2R) could be obtained as a direct response to hyperosmolar challenges and/or whether hyperosmolar challenges could augment classical vasopressin-dependent V1aR signaling...... in AQP4-dependent water permeability was observed, although osmotic challenges failed to mimic vasopressin-dependent V1aR-mediated internalization of AQP4. Direct monitoring of inositol phosphate (IP) production of V1aR-expressing COS-7 cells demonstrated an efficient vasopressin-dependent response...

  13. Assessing the variability of Red Stripe Disease in Louisiana sugarcane using precision agriculture methods

    Science.gov (United States)

    Symptoms of red stripe disease caused by Acidovorax avenae subsp. avenae in Louisiana between 1985 and 2010 were limited to the leaf stripe form which caused no apparent yield loss. During 2010, the more severe top rot form was observed, and a study was initiated to investigate the distribution of r...

  14. Osmoregulatory effects of hypophysectomy and homologous prolactin replacement in hybrid striped bass

    DEFF Research Database (Denmark)

    Jackson, Leslie F; McCormick, Stephen D; Madsen, Steffen S

    2005-01-01

    The effects of ovine prolactin (oPRL) and striped bass prolactin (sbPRL; Morone saxatilis) on plasma osmolality, electrolyte balance, and gill Na+,K+-ATPase activity were investigated in hypophysectomized (Hx), freshwater (FW)-acclimated, hybrid striped bass (M. saxatilis x Morone chrysops...

  15. Color Fringes Bordering Black Stripes at the Bottom of a Swimming Pool

    Science.gov (United States)

    Fuster, Gonzalo; Rojas, Roberto; Slüsarenko, Viktor

    2016-01-01

    We have observed a nice example of chromatic dispersion due to refraction in water, in the form of color fringes bordering the black stripes that exist at the bottom of a swimming pool. Here we give a qualitative description of the phenomenon, explaining the role of the black stripes and the dispersive index of refraction of water.

  16. Genetics of leaf and stripe rust resistance in a bread wheat cultivar ...

    Indian Academy of Sciences (India)

    MYT), Mexico, has shown resistance to leaf rust and stripe rust in the Indian ... rust resistance against. -isogenic line genes present Leaf rust. Stripe rust. Origin. Source. Parentage. Tonichi. –. TR. 10.0. Mexico. RAMC CAR422/Anahuac75. CSP44. Lr48 .... separately have been reported earlier by several authors. Table 2.

  17. Genetics of adult plant stripe rust resistance in CSP44, a selection ...

    Indian Academy of Sciences (India)

    This suggests the presence of nonhypersensitive adult plant stripe rust resistance in the line CSP44. The evaluation of F1, F2 and F3 generations and F6 SSD families from the cross of CSP44 with susceptible wheat cultivar WL711 for stripe rust severity indicated that the resistance in CSP44 is based on two genes showing ...

  18. Genetics of adult plant stripe rust resistance in CSP44, a selection ...

    Indian Academy of Sciences (India)

    Unknown

    Wheat line CSP44, a selection from an Australian bread wheat cultivar Condor, has shown resistance to stripe rust in. India since the last twenty years. Seedlings and adult plants of CSP44 showed susceptible infection types against stripe rust race 46S119 but displayed average terminal disease severity of 2.67 on adult ...

  19. Comparisons of egg quality traits, egg weight loss and hatchability between striped and normal duck eggs.

    Science.gov (United States)

    Yuan, J; Wang, B; Huang, Z; Fan, Y; Huang, C; Hou, Z

    2013-01-01

    1. The egg quality of striped and normal duck eggs was compared to determine why striped eggs show decreased hatchability. A total of 430 eggs, obtained from a Pekin duck breeder flock aged 50-65 wks, were used in three experiments. The eggs were weighed and assigned randomly to measure egg quality traits, egg weight (EW) loss and hatchability during incubation. 2. There were no significant differences between egg types in terms of egg shape index, eggshell strength and thickness, albumen height, Haugh unit, yolk colour, weight of the eggshell with or without membranes, calcium, phosphorus, copper and manganese contents in the eggshell (with the inner and outer membranes or without the inner membrane), albumen weight, dry matter of albumen, crude protein (CP) of thick albumen and pH of the thick albumen. 3. The weight of eggshells with membranes, weight of thick albumen and CP of thin albumen in striped eggs were lower than those in normal eggs. 4. The thin albumen in striped eggs was heavier than that in normal eggs. The pH of the thin albumin in striped egg was significantly higher than that in normal eggs. 5. There were no significant differences in EW loss during incubation or duckling weight between striped and normal eggs. However, the hatchability of striped eggs was lower. 6. The lower weight of the eggshell inner membrane and thick albumen, lower CP content and higher pH in the thin albumen of striped eggs might contribute to lower hatchability.

  20. Mapping genes for resistance to stripe rust in spring wheat landrace PI 480035

    Science.gov (United States)

    Stripe rust caused by Puccinia striiformis Westend. f. sp. tritici Erikks. is an economically important disease of wheat (Triticum aestivum L.). Hexaploid spring wheat landrace PI 480035 was highly resistant to stripe rust in the field in Washington during 2011 and 2012. The objective of this resear...

  1. Contributions to the validation of the ASTEC V1 code

    International Nuclear Information System (INIS)

    Constantin, Marin; Rizoiu, Andrei; Turcu, Ilie

    2004-01-01

    In the frame of PHEBEN2 project (Validation of the severe accidents codes for applications to nuclear power plants, based on the PHEBUS FP experiments), a project developed within the EU research Frame Program 5 (FP5), the INR-Pitesti's team has received the task of determining the ASTEC code sensitivity. The PHEBEN2 project has been initiated in 1998 and gathered 13 partners from 6 EU member states. To the project 4 partners from 3 candidate states (Hungary, Bulgaria and Romania) joined later. The works were contracted with the European Commission (under FIKS-CT1999-00009 contract) that supports financially the research effort up to about 50%. According to the contract provisions, INR's team participated in developing the Working Package 1 (WP1) which refers to validation of the integral computation codes that use the PHOEBUS experimental data and the Working Package 3 (WP3) referring to the evaluation of the codes to be applied in nuclear power plants for risk evaluation, nuclear safety margin evaluation and determination/evaluation of the measures to be adopted in case of severe accident. The present work continues the efforts to validate preliminarily the ASTEC code. Focused are the the stand-alone sensitivity analyses applied to two most important modules of the code, namely DIVA and SOPHAEROS

  2. Mice as stowaways? Colonization history of Danish striped field mice.

    Science.gov (United States)

    Andersen, Liselotte Wesley; Jacobsen, Magnus; Vedel-Smith, Christina; Jensen, Thomas Secher

    2017-07-01

    Species from the steppe region of Eastern Europe likely colonized northwestern Europe in connection with agriculture after 6500 BP. The striped field mouse ( Apodemus agrarius Pallas, 1783), is a steppe-derived species often found in human crops. It is common on the southern Danish islands of Lolland and Falster, which have been isolated from mainland Europe since approximately 10 300-8000 BP. Thus, this species could have been brought in with humans in connection with agriculture, or it could be an earlier natural invader. We sequenced 86 full mitochondrial genomes from the northwestern range of the striped field mouse, analysed phylogenetic relationships and estimated divergence time. The results supported human-induced colonization of Denmark in the Subatlantic or Subboreal period. A newly discovered population from Central Jutland in Denmark diverged from Falster approximately 100-670 years ago, again favouring human introduction. One individual from Sweden turned out to be a recent introduction from Central Jutland. © 2017 The Author(s).

  3. Systemic sarcocystosis in a striped skunk (Mephitis mephitis).

    Science.gov (United States)

    Burcham, G N; Ramos-Vara, J A; Vemulapalli, R

    2010-05-01

    A striped skunk with neurological signs was euthanized and examined via necropsy. Histologically, protozoa were found in multiple tissues. Protozoal schizonts measured 15 to 25 mum in diameter and contained 4 to 6 mum crescent-shaped merozoites. Protozoa were associated with necrosis and inflammation in the lung, brain, liver, and nasal epithelium. Immunohistochemistry labeled protozoa strongly positive for Sarcocystis neurona. Polymerase chain reaction-amplified products from the protozoan were 99.6% identical to the corresponding portion of the nuclear small subunit ribosomal RNA gene of S neurona. S neurona origin was further confirmed by amplifying a 451-base pair DNA fragment from the skunk lung, which differed by just 2 or 3 base pairs from the small subunit ribosomal RNA gene of S neurona. Striped skunks act as intermediate and aberrant hosts for S neurona; however, S neurona has rarely been found in extraneural tissues in any species, and systemic sarcocystosis has not been reported in skunks. Additionally, canine distemper virus infection was confirmed with histopathology and immunohistochemistry. Concurrent canine distemper suggests that immunosuppression may have played a role in S neurona infection in this skunk.

  4. Periaqueductal gray knockdown of V2, not V1a and V1b receptor influences nociception in the rat. yj6676@yahoo.com.

    Science.gov (United States)

    Yang, Jun; Yang, Yu; Chen, Jian-Min; Wang, Gen; Xu, Hong-Tao; Liu, Wen-Yan; Lin, Bao-Cheng

    2007-01-01

    Our pervious study has proved that arginine vasopressin (AVP) in periaqueductal gray (PAG) plays a role in antinociception. After establishing a model of local special gene knockdown, the nociceptive effect of vasopressin receptor subunit in PAG was investigated in the rat. Microinjection of short-interfering RNA (siRNA) into PAG, which targeted vasopressin receptor subtypes (V(1a), V(1b) and V(2)), locally weakened the associated mRNA expression and depressed the related receptor synthesis in a dose-dependent manner, in which the significant inhibitive effect occurred on from 7th day to 14th day following 1microg or 2microg siRNA administration. PAG knockdown of V(2) receptor gene markedly decreased pain threshold in from 6th day to 13th day after siRNA administration, whereas local knockdown of either V(1a) or V(1b) receptor gene could not influence pain threshold. The data suggest that V(2) rather than V(1a) and V(1b) receptor in PAG involves in nociception.

  5. Margatoxin binds to a homomultimer of K(V)1.3 channels in Jurkat cells. Comparison with K(V)1.3 expressed in CHO cells.

    Science.gov (United States)

    Helms, L M; Felix, J P; Bugianesi, R M; Garcia, M L; Stevens, S; Leonard, R J; Knaus, H G; Koch, R; Wanner, S G; Kaczorowski, G J; Slaughter, R S

    1997-03-25

    Voltage-gated potassium (K(V)) channels play key roles in setting the resting potential and in the activation cascade of human peripheral T lymphocytes. Margatoxin (MgTX), a 39-amino acid peptide from Centruroides margaritatus, is a potent inhibitor of lymphocyte K(V) channels. The binding of monoiodotyrosinyl margatoxin ([125I]MgTX) to plasma membranes prepared from either Jurkat cells, a human leukemic T cell line, or CHO cells stably transfected with the Shaker-type voltage-gated K+ channel, K(V)1.3, has been used to investigate the properties of lymphocyte K(V) channels. These data were compared with [125I]MgTX binding to heterotetrameric K(V) channels in rat brain synaptic plasma membranes [Knaus, H. G., et al. (1995) Biochemistry 34, 13627-13634]. The affinity for [125I]MgTX is 100-200 fM in either Jurkat or CHO/K(V)1.3 membranes, and the receptor density is 20-120 fmol/mg in Jurkat membranes or 1000 fmol/mg in CHO/K(V)1.3 membranes. In contrast to rat brain, [125I]MgTX binding to Jurkat and CHO/K(V)1.3 membranes exhibits an absolute requirement for K+, with no potentiation of binding by Na+. K(V)1.3 was the only K(V)1 series channel present in either CHO/K(V)1.3 or Jurkat plasma membranes as determined by immunoprecipitation of [125I]MgTX binding or by Western blot analyses using sequence-specific antibodies prepared against members of the K(V)1 family. The relative potencies of a series of peptidyl K(V) channel inhibitors was essentially the same for inhibition of [125I]MgTX binding to Jurkat, CHO, or rat brain membranes and for blocking 86Rb+ efflux from the CHO/K(V)1.3 cells, except that alpha-dendrotoxin was more potent at blocking binding to rat brain membranes than in the other assays. The characteristics of [125I]MgTX binding, the antibody profiles, and the effects of the peptidyl K(V) inhibitors all indicate that the [125I]MgTX receptor in Jurkat lymphocytes is comprised of a homomultimer of K(V)1.3, unlike the heteromultimeric arrangement of the

  6. NMR resonance assignments of a hypoallergenic isoform of the major birch pollen allergen Bet v 1.

    Science.gov (United States)

    Ahammer, Linda; Grutsch, Sarina; Wallner, Michael; Ferreira, Fatima; Tollinger, Martin

    2017-10-01

    In Northern America and Europe a great number of people are suffering from birch pollen allergy and pollen related food allergies. The trigger for these immunological reactions is the 17.5 kDa major birch pollen allergen Bet v 1, which belongs to the family of PR-10 (pathogenesis-related) proteins. In nature, Bet v 1 occurs as a mixture of various isoforms that possess different immunological properties despite their high sequence identities. Bet v 1.0102 (Bet v 1d), which is investigated here, is a hypoallergenic isoform of Bet v 1 and a potential candidate for allergen-specific immunotherapy. We assigned the backbone and side chain 1 H, 13 C and 15 N resonances of this protein and predicted its secondary structure. The NMR-chemical shift data indicate that Bet v 1.0102 is composed of three α-helices and a seven stranded β-sheet, in agreement with the known structure of the hyperallergenic isoform Bet v 1.0101 (Bet v 1a). Our resonance assignments create the foundation for detailed characterization of the dynamic properties of Bet v 1 isoforms by NMR relaxation measurements.

  7. History and evaluation of the operation of Jaslovske Bohunice V-1 NPP Unit 1

    International Nuclear Information System (INIS)

    Obert, M.; Kovac, V.

    2007-01-01

    The following information is provided: Deadline and reasons for discontinuation of operation of V-1 reactor unit 1; improvements of V-1 reactor units in early 1990s ('Minor Reconstruction'); 'Gradual Reconstruction': underlying requirements, systems concerned, implementation process and results; technical and economic indicators of operation of V-1 unit 1; reasons for and way of transfer of the V-1 NPP to a new company within the process of privatization of the Slovenske elektrarne Inc. utility; and, in conclusion, assessment of the operation and outline of planned activities within the decommissioning process. (orig.)

  8. Stripe to slab confinement for the linearization of macromolecules in nanochannels.

    Science.gov (United States)

    Benková, Zuzana; Námer, Pavol; Cifra, Peter

    2015-03-21

    We investigated the recently suggested advantageous analysis of chain linearization experiments with macromolecules confined in a stripe-like channel (Huang and Battacharya, EPL, 2014, 106, 18004) using Monte Carlo simulations. The enhanced chain extension in a stripe, which is due to the significant excluded volume interactions between the monomers in two dimensions, weakens considerably on transition to an experimentally feasible slit-like channel. Based on the chain extension-confinement strength dependence and the structure factor behavior for a chain in a stripe, we infer the excluded volume regime (de Gennes regime) typical for two-dimensional systems. On widening of the stripe in a direction perpendicular to the stripe plane, i.e. on the transition to the slab geometry, the advantageous chain extension decreases and a Gaussian regime is observed for not very long semiflexible chains. The evidence for pseudo-ideality in confined chains is based on four indicators: the extension curves, variation of the extension with the persistence length P, estimated limits for the regimes in the investigated systems, and the structure factor behavior. The slab behavior can be observed when the two-dimensional stripe (originally of a one-monomer thickness) reaches a reduced thickness D larger than approximately D/P ≈ 0.2 in the third dimension. This maximum height of a slab at which the advantage of a stripe is retained is very low and has implications for DNA linearization experiments.

  9. Intervertebral disk disease in 3 striped skunks (Mephitis mephitis).

    Science.gov (United States)

    Krauss, Maximiljan W; Benato, Livia; Wack, Allison; McDonnell, John J; Schoemaker, Nico J; Westerhof, Ineke; Bronson, Ellen; Gielen, Ingrid; Van Caelenberg, Annemie; Hellebuyck, Tom; Meij, Björn P; De Decker, Steven

    2014-07-01

    To describe diagnostic findings, surgical technique, and outcome in 3 striped skunks (Mephitis mephitis) with a history of paraparesis. Case series. Skunks (n = 3) with paraparesis. Neurologic examination revealed upper motor neuron disease (T2-L2) in 2 skunks and lower motor neuron disease (L3-S3) in 1 skunk. Diagnostic imaging included radiography, myelography, CT, and MRI and confirmed intervertebral disk herniation (IVDH) in each skunk. Because initial treatment with pain medication and cage rest did not result in lasting improvement, spinal surgery was performed. Hemilaminectomy (2 skunks) and dorsal laminectomy (1 skunk) was performed with removal of extruded disk material. The skunks improved after surgery but all had minor residual neurologic deficits when examined at various times postoperatively. Thoracolumbar intervertebral disk herniation occurs in skunks, and must be included in the differential diagnosis of paraparesis. © Copyright 2014 by The American College of Veterinary Surgeons.

  10. Explanation of the nature of stripe magnetic anomalies without inversions

    Science.gov (United States)

    Melikhov, Vjacheslav; Lygin, Ivan; Sokolova, Tatiana

    2014-05-01

    Several scientists of different branches express doubts on the validity of the Earth's geomagnetic field inversions hypothesis [Vine F.J., Matthews D.H, 1963]. Presently a lot of information allows to link the appearance of stripe magnetic anomalies of both signs with the spreading fracture structure (horizontal segmentation of intrusions and sills, breaks in the strong crust, vertical movements of blocks), remagnetization near the borders of the blocks, hydrothermal activity. Non-inversion mechanism of origin of linear stripe magnetic anomalies in the oceans could be explained as follows. Ascending asthenospheric flows have been enrich with volatile components, become thinner, pressure on the walls of the lithospheric plates grows and part them. When it approaches the surface: - horizontal tensile pressure grows, - lithostatic pressure in the vertical column of rocks decreases, - crust strong upper layer flakes away and begins to move horizontally. It is important that thin magmatic and magnetic layers (further layers) of the newly formed strong upper crust move away from the ridge axis. The structure of such layers forms by horizontal stresses and so consist of the hills and depressions sequences or updiped and downdiped blocks heaped each other. This layer is the main source of the magnetic field and cannot be approximated by a horizontal homogeneous plate as it proved before. In the mid-ocean ridges (MOR) the folding periods of layer depend on its thickness and rigidity and horizontal velocity of spreading. The higher velocity - the longer periods of roughness are and contrary. Same pattern is observed for the stripe magnetic anomalies distribution. The magnetic field of the MOR forms there due to young lava flows which get thermoremanent magnetization according the current direction of geomagnetic field. Partial destruction of the relief, overlaying and creation of the new shapes occur when new magma penetrates the moved magnetic layer. The process entails

  11. Rogue wave and a pair of resonance stripe solitons to a reduced (3+1)-dimensional Jimbo-Miwa equation

    Science.gov (United States)

    Zhang, Xiaoen; Chen, Yong

    2017-11-01

    In this paper, a combination of stripe soliton and lump soliton is discussed to a reduced (3+1)-dimensional Jimbo-Miwa equation, in which such solution gives rise to two different excitation phenomena: fusion and fission. Particularly, a new combination of positive quadratic functions and hyperbolic functions is considered, and then a novel nonlinear phenomenon is explored. Via this method, a pair of resonance kink stripe solitons and rogue wave is studied. Rogue wave is triggered by the interaction between lump soliton and a pair of resonance kink stripe solitons. It is exciting that rogue wave must be attached to the stripe solitons from its appearing to disappearing. The whole progress is completely symmetry, the rogue wave starts itself from one stripe soliton and lose itself in another stripe soliton. The dynamic properties of the interaction between one stripe soliton and lump soliton, rogue wave are discussed by choosing appropriate parameters.

  12. Static and dynamic magnetic properties of stripe-patterned Fe20Ni80 soft magnetic films

    Science.gov (United States)

    Zhu, Zengtai; Feng, Hongmei; Cheng, Xiaohong; Xie, Hongkang; Liu, Qingfang; Wang, Jianbo

    2018-01-01

    Stripe-patterned soft magnetic Fe20Ni80 films were fabricated on silicon substrate via radio frequency magnetron sputtering technology. The static and dynamic magnetic properties of samples were measured by a vibrating sample magnetometer and vector network analyzer. The vector network analyzer ferromagnetic resonance technique was used to analyze the experimental results, which showed that damping and in-plane uniaxial anisotropy can be tuned significantly for the samples with various stripe widths from 5 to 20 µm. A stripe-shaped anisotropy model was used to analyze the experimental results, which were in accord with the theoretical predictions. Moreover, the variation of damping was investigated in detail.

  13. Striped Bass Spawning in Non-Estuarine Portions of the Savannah River

    Energy Technology Data Exchange (ETDEWEB)

    Martin, D.; Paller, M.

    2007-04-17

    Historically, the estuarine portions of the Savannah River have been considered to be the only portion of the river in which significant amounts of striped bass (Morone saxatilis) spawning normally occur. A reexamination of data from 1983 through 1985 shows a region between River Kilometers 144 and 253 where significant numbers of striped bass eggs and larvae occur with estimated total egg production near that currently produced in the estuarine reaches. It appears possible that there are two separate spawning populations of striped bass in the Savannah River.

  14. Magnetic stripes and holes: Complex domain patterns in perforated films with weak perpendicular anisotropy

    Directory of Open Access Journals (Sweden)

    F. Valdés-Bango

    2017-05-01

    Full Text Available Hexagonal antidot arrays have been patterned on weak perpendicular magnetic anisotropy NdCo films by e-beam lithography and lift off. Domain structure has been characterized by Magnetic Force Microscopy at remanence. On a local length scale, of the order of stripe pattern period, domain configuration is controlled by edge effects within the stripe pattern: stripe domains meet the hole boundary at either perpendicular or parallel orientation. On a longer length scale, in-plane magnetostatic effects dominate the system: clear superdomains are observed in the patterned film with average in-plane magnetization along the easy directions of the antidot array, correlated over several antidot array cells.

  15. Magnetic stripes and holes: Complex domain patterns in perforated films with weak perpendicular anisotropy

    Science.gov (United States)

    Valdés-Bango, F.; Vélez, M.; Alvarez-Prado, L. M.; Alameda, J. M.; Martín, J. I.

    2017-05-01

    Hexagonal antidot arrays have been patterned on weak perpendicular magnetic anisotropy NdCo films by e-beam lithography and lift off. Domain structure has been characterized by Magnetic Force Microscopy at remanence. On a local length scale, of the order of stripe pattern period, domain configuration is controlled by edge effects within the stripe pattern: stripe domains meet the hole boundary at either perpendicular or parallel orientation. On a longer length scale, in-plane magnetostatic effects dominate the system: clear superdomains are observed in the patterned film with average in-plane magnetization along the easy directions of the antidot array, correlated over several antidot array cells.

  16. A V1-vascular vasopressin antagonist suitable for radioiodination and photoaffinity labeling

    International Nuclear Information System (INIS)

    Thibonnier, M.; Chehade, N.; Hinko, A.

    1990-01-01

    We have previously characterized the V1-vascular arginine vasopressin (AVP) receptors of human platelets. We now report on a radiomonoiodinated and photoreactive V1-vascular AVP antagonist (V1-ag) to be used for the purification of human V1-vascular AVP receptors. The V1-ag, d(CH2)5Tyr(Me)Tyr(NH2)AVP was modified by radiomonoiodination of d(CH2)5-Tyr(Me)Tyr(NH2)AVP with the Iodogen technique, and derivatization of d(CH2)5Tyr(Me)Tyr[125I](NH2)-AVP with the photoreactive crosslinker, N-hydroxysuccinimidyl-4-azidobenzoate (HSAB) (each step included HPLC purification). In competition experiments, the affinity of these V1-ag for the human platelet AVP receptors remained excellent. Irreversible photoaffinity labeling of the platelet V1-vascular AVP receptor was successfully achieved by UV lamp exposure (365 nm, 20 min). Thus, AzBz-d(CH2)5Tyr(Me)Tyr[125I](NH2)AVP is a promising tool to use for the purification of human V1-vascular AVP receptors

  17. USEEIO v1.1 - Elementary Flows and Life Cycle Impact Assessment (LCIA) Characterization Factors

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset is part of the USEEIO v1.1 model release. It provides the elementary flows used in the USEEIO v1.1 Satellite Tables (DOI: 10.23719/1365565) and their...

  18. Sequence analysis of RNA3 of Maize stripe virus associated with stripe disease of sorghum (Sorghum bicolor in India

    Directory of Open Access Journals (Sweden)

    Kalanghad Puthankalam SRINIVAS

    2014-05-01

    Full Text Available Maize stripe virus (MSpV, one of the distinct species of the genus Tenuivirus, has been associated with stripe disease of sorghum in India. In this study, we report the complete sequence analysis of ambisense RNA3 of four MSpV isolates associated with this disease, to confirm its correct identity. The RNA3 of four MSpV-Sorg isolates is 2357 nucleotides in length with two ORFs, one in virion sense (594 nucleotides, non-structural protein 3, NS3 and the other in complementary sense (951 nucleotides, coat protein, CP. The intergenic region between these two ORFs is 653 nucleotides in length, which is rich in U and A residues. The deduced molecular weights of NS3 and CP are ≈22 and ≈34 kDa, respectively. RNA3 has ≈82% sequence identity at nucleotide level with RNA3 of MSpV infecting maize in Florida, USA and Reunion. NS3 and CP ORFs shared ≈94% and ≈95% identities at amino acid levels, respectively with MSpV isolates of maize from Florida and Reunion. The internal non-coding region between two ORFs has 67–68% identity at nucleotide level with the reported MSpV isolates from Florida and Reunion. The sequence identity was more than ≈98% among the four isolates of MSpV-Sorg. Compared to maize-infecting MSpV isolates in USA and Reunion, the sorghum-infecting MSpV isolates in India had more amino acid substitutions in both NS3 and CP. This is the first report of complete sequence analysis of MSpV RNA3 from Asia.

  19. Improving sustainability of striped catfish (Pangasianodon hypophthalmus) farming in the Mekong Delta, Vietnam through recirculation technology

    NARCIS (Netherlands)

    Nguyen, Nhut

    2016-01-01

    The aim of this thesis was to document improvements in sustainability indicators of striped catfish (Pangasianodon hypophthalmus, Sauvage, 1878) production through the application of recirculation and waste treatment techniques. To be able to document improvements in sustainability, in each system

  20. Nonlocal Electron-Phonon Interaction as a Source of Dynamic Charge Stripes in the Cuprates

    Directory of Open Access Journals (Sweden)

    Claus Falter

    2012-01-01

    small pockets with reduced doping. We argue that the incompressibility of the orbital and simultaneously the compressibility of the orbital in the pseudogap state seem to be required to nucleate dynamic stripes.

  1. Striped Marlin Hardparts and Gonads Collected by the PIRO Hawaii Longline Observer Program

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Compilation of all samples collected from striped marlin (Tetrapturus audax) collected and brought to the Aiea Heights Research Facility by the PIRO Hawaii Longline...

  2. Complementary Response of Static Spin-Stripe Order and Superconductivity to Nonmagnetic Impurities in Cuprates

    Science.gov (United States)

    Guguchia, Z.; Roessli, B.; Khasanov, R.; Amato, A.; Pomjakushina, E.; Conder, K.; Uemura, Y. J.; Tranquada, J. M.; Keller, H.; Shengelaya, A.

    2017-08-01

    We report muon-spin rotation and neutron-scattering experiments on nonmagnetic Zn impurity effects on the static spin-stripe order and superconductivity of the La214 cuprates. Remarkably, it was found that, for samples with hole doping x ≈1 /8 , the spin-stripe ordering temperature Tso decreases linearly with Zn doping y and disappears at y ≈4 %, demonstrating a high sensitivity of static spin-stripe order to impurities within a CuO2 plane. Moreover, Tso is suppressed by Zn in the same manner as the superconducting transition temperature Tc for samples near optimal hole doping. This surprisingly similar sensitivity suggests that the spin-stripe order is dependent on intertwining with superconducting correlations.

  3. Evaluation of the effectiveness of centerline rumble stripes on rural roads.

    Science.gov (United States)

    2015-03-01

    This report documents the site characteristics, constructability, summary of audibility testing, and maintenance response of centerline rumble : stripes at two locations: US Route 4 in Mendon-Killington and VT Route 105 in Sheldon. : The primary obje...

  4. Histopathologic correlates of radial stripes on MR images in lysosomal storage disorders.

    NARCIS (Netherlands)

    Voorn, J.P. van der; Pouwels, P.J.; Kamphorst, W.; Powers, J.M.; Lammens, M.M.Y.; Barkhof, F.; Knaap, M.S. van der

    2005-01-01

    BACKGROUND AND PURPOSE: Radially oriented hypointense stripes in hyperintense cerebral white matter are recognized on T2-weighted images of certain lysosomal storage disorders. We compared in vivo and postmortem MR imaging with histopathologic findings in three patients with metachromatic

  5. Yr32 for resistance to stripe (yellow) rust present in the wheat cultivar Carstens V

    DEFF Research Database (Denmark)

    Eriksen, L.; Afshari, F.; Christiansen, M.J.

    2004-01-01

    Stripe or yellow rust of wheat, caused by Puccinia striiformis f. sp. tritici, is an important disease in many wheat-growing regions of the world. A number of major genes providing resistance to stripe rust have been used in breeding, including one gene that is present in the differential tester...... Carstens V. The objective of this study was to locate and map a stripe rust resistance gene transferred from Carstens V to Avocet S and to use molecular tools to locate a number of genes segregating in the cross Savannah/Senat. One of the genes present in Senat was predicted to be a gene that is present...... in Carstens V. For this latter purpose, stripe rust response data from both seedling and field tests on a doubled haploid population consisting of 77 lines were compared to an available molecular map for the same lines using a non-parametric quantitative trait loci (QTL) analysis. Results obtained in Denmark...

  6. Propagation of dark stripe beams in nonlinear media: Snake instability and creation of optical vortices

    DEFF Research Database (Denmark)

    Mamaev, A.V.; Saffman, M.; Zozulya, A.A.

    1996-01-01

    We analyze the evolution of (1+1) dimensional dark stripe beams in bulk media with a photorefractive nonlinear response. These beams, including solitary wave solutions, are shown to be unstable with respect to symmetry breaking and formation of structure along the initially homogeneous coordinate....... Experimental results show the complete sequence of events starting from self-focusing of the stripe, its bending due to the snake instability, and subsequent decay into a set of optical vortices....

  7. Topographic Organization of Inferior Olive Projections to the Zebrin II Stripes in the Pigeon Cerebellar Uvula

    Directory of Open Access Journals (Sweden)

    Iulia Craciun

    2018-03-01

    Full Text Available This study was aimed at mapping the organization of the projections from the inferior olive (IO to the ventral uvula in pigeons. The uvula is part of the vestibulocerebellum (VbC, which is involved in the processing of optic flow resulting from self-motion. As in other areas of the cerebellum, the uvula is organized into sagittal zones, which is apparent with respect to afferent inputs, the projection patterns of Purkinje cell (PC efferents, the response properties of PCs and the expression of molecular markers such as zebrin II (ZII. ZII is heterogeneously expressed such that there are sagittal stripes of PCs with high ZII expression (ZII+, alternating with sagittal stripes of PCs with little to no ZII expression (ZII−. We have previously demonstrated that a ZII+/− stripe pair in the uvula constitutes a functional unit, insofar as the complex spike activity (CSA of all PCs within a ZII+/− stripe pair respond to the same type of optic flow stimuli. In the present study we sought to map the climbing fiber (CF inputs from the IO to the ZII+ and ZII− stripes in the uvula. We injected fluorescent Cholera Toxin B (CTB of different colors (red and green into ZII+ and ZII− bands of functional stripe pair. Injections in the ZII+ and ZII− bands resulted in retrograde labeling of spatially separate, but adjacent regions in the IO. Thus, although a ZII+/− stripe pair represents a functional unit in the pigeon uvula, CF inputs to the ZII+ and ZII− stripes of a unit arise from separate regions of the IO.

  8. Stripe patterns in a granular system induced by slow deformation of its container

    OpenAIRE

    Kitsunezaki, So; Kurumatani, Akemi

    2001-01-01

    We investigate the formation of stripe patterns that appear on the surface of a dry granular system as the container is deformed very slowly. In an experimental study using nearly mono-disperse glass beads, we found that many faults develop beneath t he surface. Our results show that the spacing of stripes is independent of the system size and does not depend significantly on the grain size.

  9. Co-evolutionary dynamics of the bacteria Vibrio sp. CV1 and phages V1G, V1P1, and V1P2: implications for phage therapy.

    Science.gov (United States)

    Barbosa, Camilo; Venail, Patrick; Holguin, Angela V; Vives, Martha J

    2013-11-01

    Bacterial infections are the second largest cause of mortality in shrimp hatcheries. Among them, bacteria from the genus Vibrio constitute a major threat. As the use of antibiotics may be ineffective and banned from the food sector, alternatives are required. Historically, phage therapy, which is the use of bacteriophages, is thought to be a promising option to fight against bacterial infections. However, as for antibiotics, resistance can be rapidly developed. Since the emergence of resistance is highly undesirable, a formal characterization of the dynamics of its acquisition is mandatory. Here, we explored the co-evolutionary dynamics of resistance between the bacteria Vibrio sp. CV1 and the phages V1G, V1P1, and V1P2. Single-phage treatments as well as a cocktail composed of the three phages were considered. We found that in the presence of a single phage, bacteria rapidly evolved resistance, and the phages decreased their infectivity, suggesting that monotherapy may be an inefficient treatment to fight against Vibrio infections in shrimp hatcheries. On the contrary, the use of a phage cocktail considerably delayed the evolution of resistance and sustained phage infectivity for periods in which shrimp larvae are most susceptible to bacterial infections, suggesting the simultaneous use of multiple phages as a serious strategy for the control of vibriosis. These findings are very promising in terms of their consequences to different industrial and medical scenarios where bacterial infections are present.

  10. Cytokine-mediated downregulation of vasopressin V(1A) receptors during acute endotoxemia in rats.

    Science.gov (United States)

    Bucher, Michael; Hobbhahn, Jonny; Taeger, Kai; Kurtz, Armin

    2002-04-01

    The reduced pressure response to vasopressin during acute sepsis has directed our interest to the regulation of vasopressin V(1A) receptors. Rats were injected with lipopolysaccharide for induction of experimental gram-negative sepsis. V(1A) receptor gene expression was downregulated in the liver, lung, kidney, and heart during endotoxemia. Inasmuch as the concentrations of proinflammatory cytokines such as interleukin-1beta, tumor necrosis factor-alpha, and interferon-gamma were highly increased during sepsis, the influence of these cytokines on V(1A) receptor expression was investigated in primary cultures of hepatocytes and in the aortic vascular smooth muscle cell line A7r5. V(1A) receptor expression was downregulated by the cytokines in a nitric oxide-independent manner. Blood pressure dose-response studies after injection of endotoxin showed a diminished responsiveness to the selective V(1) receptor agonist Phe(2),Ile(3),Orn(8)-vasopressin. Our data show that sepsis causes a downregulation of V(1A) receptors and suggest that this effect is likely mediated by proinflammatory cytokines. We propose that this downregulation of V(1A) receptors contributes to the attenuated responsiveness of blood pressure in response to vasopressin and, therefore, contributes to the circulatory failure in septic shock.

  11. A Predictive Study of the Dynamic Development of the P-Wave Terminal Force in Lead V1 in the Electrocardiogram in Relation to Long-Term Prognosis in Non-ST-Segment Elevation Acute Coronary Syndrome Patients during Hospitalization.

    Science.gov (United States)

    Li, Qiao; Gu, Li-Dan; Zhang, Chen; Liu, Wei; Peng, Yong; Chai, Hua; Xu, Yuan-Ning; Wei, Jia-Fu; Chen, Mao; Huang, De-Jia

    2015-11-01

    Changes in the ECG indicator PtfV1 reflect left atrial pressure and left ventricular diastolic function in NSTE-ACS patients during hospitalization. The value of PtfV1 in the evaluation of long-term prognosis in NSTE-ACS is still not clear. The purpose of this study was to investigate the relationship between the dynamic changes in P-wave terminal force in lead V1(PtfV1) in the ECG of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) patients during hospitalization and the long-term major adverse cardiovascular events (MACEs) of patients. A total of 595 patients who received coronary angiography and were confirmed as NSTE-ACS in the coronary heart disease database of Department of Cardiology of West China Hospital were continuously included. The PtfV1 and other clinical data at admission and discharge were collected and dynamically observed. The end events of follow-up observation were MACEs. Follow-up was performed on 595 patients for 24.71 ± 1.95 months. There were 127 PtfV1(+) and 468 PtfV1(-) at admission, and the incidences of MACEs were 14.2% and 11.1%, respectively (P = 0.731). Compared with patients with persistent PtfV1(-) ECG at admission and discharge, 53 patients with persistent PtfV1(+) ECG at admission and discharge had increased risk for MACEs (HR: 2.221, 95% CI: 1.072-4.601, P = 0.032); 94 patients with new PtfV1(+) ECG at discharge also had significantly increased risk for MACEs (HR: 2.993, 95% CI: 1.660-5.397, P = 0.000). NSTE-ACS patients with persistent PtfV1(+) ECG indicators at admission and discharge and new PtfV1(+) at discharge had significantly increased risk of MACEs. © 2015 Wiley Periodicals, Inc.

  12. Are stripes beneficial? Dazzle camouflage influences perceived speed and hit rates.

    Directory of Open Access Journals (Sweden)

    Bettina von Helversen

    Full Text Available In the animal kingdom, camouflage refers to patterns that help potential prey avoid detection. Mostly camouflage is thought of as helping prey blend in with their background. In contrast, disruptive or dazzle patterns protect moving targets and have been suggested as an evolutionary force in shaping the dorsal patterns of animals. Dazzle patterns, such as stripes and zigzags, are thought to reduce the probability with which moving prey will be captured by impairing predators' perception of speed. We investigated how different patterns of stripes (longitudinal-i.e., parallel to movement direction-and vertical-i.e., perpendicular to movement direction affect the probability with which humans can hit moving objects and if differences in hitting probability are caused by a misperception of speed. A first experiment showed that longitudinally striped objects were hit more often than unicolored objects. However, vertically striped objects did not differ from unicolored objects. A second study examining the link between perceived speed and hitting probability showed that longitudinally and vertically striped objects were both perceived as moving faster and were hit more often than unicolored objects. In sum, our results provide evidence that striped patterns disrupt the perception of speed, which in turn influences how often objects are hit. However, the magnitude and the direction of the effects depend on additional factors such as speed and the task setup.

  13. Electronic warfare receivers and receiving systems

    CERN Document Server

    Poisel, Richard A

    2014-01-01

    Receivers systems are considered the core of electronic warfare (EW) intercept systems. Without them, the fundamental purpose of such systems is null and void. This book considers the major elements that make up receiver systems and the receivers that go in them.This resource provides system design engineers with techniques for design and development of EW receivers for modern modulations (spread spectrum) in addition to receivers for older, common modulation formats. Each major module in these receivers is considered in detail. Design information is included as well as performance tradeoffs o

  14. Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes NaV1.9, NaV1.7 and NaV1.1

    Science.gov (United States)

    Touska, Filip; Sattler, Simon; Malsch, Philipp; Lewis, Richard J.; Zimmermann, Katharina

    2017-01-01

    Ciguatoxins (CTXs) are marine toxins that cause ciguatera fish poisoning, a debilitating disease dominated by sensory and neurological disturbances that include cold allodynia and various painful symptoms as well as long-lasting pruritus. Although CTXs are known as the most potent mammalian sodium channel activator toxins, the etiology of many of its neurosensory symptoms remains unresolved. We recently described that local application of 1 nM Pacific Ciguatoxin-1 (P-CTX-1) into the skin of human subjects induces a long-lasting, painful axon reflex flare and that CTXs are particularly effective in releasing calcitonin-gene related peptide (CGRP) from nerve terminals. In this study, we used mouse and rat skin preparations and enzyme-linked immunosorbent assays (ELISA) to study the molecular mechanism by which P-CTX-1 induces CGRP release. We show that P-CTX-1 induces CGRP release more effectively in mouse as compared to rat skin, exhibiting EC50 concentrations in the low nanomolar range. P-CTX-1-induced CGRP release from skin is dependent on extracellular calcium and sodium, but independent from the activation of various thermosensory transient receptor potential (TRP) ion channels. In contrast, lidocaine and tetrodotoxin (TTX) reduce CGRP release by 53–75%, with the remaining fraction involving L-type and T-type voltage-gated calcium channels (VGCC). Using transgenic mice, we revealed that the TTX-resistant voltage-gated sodium channel (VGSC) NaV1.9, but not NaV1.8 or NaV1.7 alone and the combined activation of the TTX-sensitive VGSC subtypes NaV1.7 and NaV1.1 carry the largest part of the P-CTX-1-caused CGRP release of 42% and 34%, respectively. Given the contribution of CGRP to nociceptive and itch sensing pathways, our findings contribute to a better understanding of sensory symptoms of acute and chronic ciguatera that may help in the identification of potential therapeutics. PMID:28867800

  15. Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes NaV1.9, NaV1.7 and NaV1.1

    Directory of Open Access Journals (Sweden)

    Filip Touska

    2017-08-01

    Full Text Available Ciguatoxins (CTXs are marine toxins that cause ciguatera fish poisoning, a debilitating disease dominated by sensory and neurological disturbances that include cold allodynia and various painful symptoms as well as long-lasting pruritus. Although CTXs are known as the most potent mammalian sodium channel activator toxins, the etiology of many of its neurosensory symptoms remains unresolved. We recently described that local application of 1 nM Pacific Ciguatoxin-1 (P-CTX-1 into the skin of human subjects induces a long-lasting, painful axon reflex flare and that CTXs are particularly effective in releasing calcitonin-gene related peptide (CGRP from nerve terminals. In this study, we used mouse and rat skin preparations and enzyme-linked immunosorbent assays (ELISA to study the molecular mechanism by which P-CTX-1 induces CGRP release. We show that P-CTX-1 induces CGRP release more effectively in mouse as compared to rat skin, exhibiting EC50 concentrations in the low nanomolar range. P-CTX-1-induced CGRP release from skin is dependent on extracellular calcium and sodium, but independent from the activation of various thermosensory transient receptor potential (TRP ion channels. In contrast, lidocaine and tetrodotoxin (TTX reduce CGRP release by 53–75%, with the remaining fraction involving L-type and T-type voltage-gated calcium channels (VGCC. Using transgenic mice, we revealed that the TTX-resistant voltage-gated sodium channel (VGSC NaV1.9, but not NaV1.8 or NaV1.7 alone and the combined activation of the TTX-sensitive VGSC subtypes NaV1.7 and NaV1.1 carry the largest part of the P-CTX-1-caused CGRP release of 42% and 34%, respectively. Given the contribution of CGRP to nociceptive and itch sensing pathways, our findings contribute to a better understanding of sensory symptoms of acute and chronic ciguatera that may help in the identification of potential therapeutics.

  16. The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands

    Directory of Open Access Journals (Sweden)

    Breiteneder Heimo

    2008-10-01

    Full Text Available Abstract Background The major birch pollen allergen, Bet v 1, is a member of the ubiquitous PR-10 family of plant pathogenesis-related proteins. In recent years, a number of diverse plant proteins with low sequence similarity to Bet v 1 was identified. In addition, determination of the Bet v 1 structure revealed the existence of a large superfamily of structurally related proteins. In this study, we aimed to identify and classify all Bet v 1-related structures from the Protein Data Bank and all Bet v 1-related sequences from the Uniprot database. Results Structural comparisons of representative members of already known protein families structurally related to Bet v 1 with all entries of the Protein Data Bank yielded 47 structures with non-identical sequences. They were classified into eleven families, five of which were newly identified and not included in the Structural Classification of Proteins database release 1.71. The taxonomic distribution of these families extracted from the Pfam protein family database showed that members of the polyketide cyclase family and the activator of Hsp90 ATPase homologue 1 family were distributed among all three superkingdoms, while members of some bacterial families were confined to a small number of species. Comparison of ligand binding activities of Bet v 1-like superfamily members revealed that their functions were related to binding and metabolism of large, hydrophobic compounds such as lipids, hormones, and antibiotics. Phylogenetic relationships within the Bet v 1 family, defined as the group of proteins with significant sequence similarity to Bet v 1, were determined by aligning 264 Bet v 1-related sequences. A distance-based phylogenetic tree yielded a classification into 11 subfamilies, nine exclusively containing plant sequences and two subfamilies of bacterial proteins. Plant sequences included the pathogenesis-related proteins 10, the major latex proteins/ripening-related proteins subfamily, and

  17. Structural lability of Barley stripe mosaic virus virions.

    Directory of Open Access Journals (Sweden)

    Valentin V Makarov

    Full Text Available Virions of Barley stripe mosaic virus (BSMV were neglected for more than thirty years after their basic properties were determined. In this paper, the physicochemical characteristics of BSMV virions and virion-derived viral capsid protein (CP were analyzed, namely, the absorption and intrinsic fluorescence spectra, circular dichroism spectra, differential scanning calorimetry curves, and size distributions by dynamic laser light scattering. The structural properties of BSMV virions proved to be intermediate between those of Tobacco mosaic virus (TMV, a well-characterized virus with rigid rod-shaped virions, and flexuous filamentous plant viruses. The BSMV virions were found to be considerably more labile than expected from their rod-like morphology and a distant sequence relation of the BSMV and TMV CPs. The circular dichroism spectra of BSMV CP subunits incorporated into the virions, but not subunits of free CP, demonstrated a significant proportion of beta-structure elements, which were proposed to be localized mostly in the protein regions exposed on the virion outer surface. These beta-structure elements likely formed during virion assembly can comprise the N- and C-terminal protein regions unstructured in the non-virion CP and can mediate inter-subunit interactions. Based on computer-assisted structure modeling, a model for BSMV CP subunit structural fold compliant with the available experimental data was proposed.

  18. Experimental Toxoplasma gondii infection in striped skunk (Mephitis mephitis).

    Science.gov (United States)

    Quirk, Travis; Dubey, J P

    2008-06-01

    Twenty-three striped skunks (Mephitis mephitis) without demonstrable antibodies in 1:25 serum dilution in the modified agglutination test (MAT) were fed sporulated Toxoplasma gondii oocysts (9 skunks) or tissue cysts (10 skunks), and 4 skunks (controls) were not fed T. gondii. Skunks were bled before feeding T. gondii, 10 and 23- 25 days postinoculation (PI). All 9 seronegative skunks fed oocysts died of acute toxoplasmosis between 7 and 19 days PI; T. gondii tachyzoites were found in histological sections of many tissues. One of the 10 skunks fed tissue cysts and 1 of the 4 controls also died of acute toxoplasmosis days 19 and 20 PI; these animals probably became infected by ingestion of unexcysted oocysts passed in feces of skunks fed oocysts that were housed in the same room that skunks fed tissue cysts were housed. The remaining 9 skunks fed tissue cysts and the 3 controls developed only a mild illness and were killed in good health on days 23-25 PI. Antibodies to T. gondii were not found in 1:25 serum dilution of any of the 19 of 23 skunks that were alive on day 10 PI; 12 of 13 skunks had antibodies (MAT 1:80 or higher) on the day they were killed. Antibodies were not found in 1 skunk. Results indicate that skunks can develop IgG antibodies to T. gondii within 3 wk PI, and primary toxoplasmosis can be fatal in skunks.

  19. Evaluation of marked-recapture for estimating striped skunk abundance

    Science.gov (United States)

    Greenwood, R.J.; Sargeant, A.B.; Johnson, D.H.

    1985-01-01

    The mark-recapture method for estimating striped skunk (Mephitis mephitis) abundance was evaluated by systematically livetrapping a radio-equipped population on a 31.4-km2 study area in North Dakota during late April of 1977 and 1978. The study population was 10 females and 13 males in 1977 and 20 females and 8 males in 1978. Skunks were almost exclusively nocturnal. Males traveled greater nightly distances than females (3.3 vs. 2.6 km, P skunks spent on the study area. Little variation in capture probabilities was found among trap-nights. Skunks exhibited neither trap-proneness nor shyness. Capture rates in 1977 were higher for males than for females; the reverse occurred in 1978. Variation in individual capture rates was indicated among males in 1977 and among females in 1978. Ten estimators produced generally similar results, but all underestimated true population size. Underestimation was a function of the number of untrapped skunks, primarily those that spent limited time on the study area. The jackknife method produced the best estimates of skunk abundance.

  20. Characterizing the Heat Flow from Between Enceladus' Tiger Stripes

    Science.gov (United States)

    Howett, C.; Spencer, J. R.; Verbiscer, A.

    2017-12-01

    Enceladus' heat flow provides a fundamental constraint on its tidal dissipation mechanisms, orbital evolution, and the physical processes that generate the plumes. Determining the total amount of emission is proving difficult, as different techniques produce differing constraints. For example, an initial estimate of this value, 5.8±1.3 GW, was made by Spencer et al. (2006) using Cassini Composite Infrared Spectrometer (CIRS) 600 to 1100 cm-1 observations, which was refined using 10 to 600 cm-1 CIRS observations to 15.8±3.1 GW by Howett et al. (2011). However, recent reanalysis of high-spatial resolution 10 to 1100 cm-1 CIRS observations of Enceladus' active south polar region conducted by Spencer and Howett gives a heat flow of 4.64±0.23 GW. Whilst all of these heat flow estimates are much larger than those expected in a steady state, 1.1 GW (Meyer and Wisdom, 2007), their obvious discrepancy is a puzzle. In this work we seek to help understand these discrepancies by determining how much endogenic heat flow is coming from the funiscular terrain between Enceladus active tiger stripes.

  1. Strategies for Wheat Stripe Rust Pathogenicity Identified by Transcriptome Sequencing.

    Directory of Open Access Journals (Sweden)

    Diana P Garnica

    Full Text Available Stripe rust caused by the fungus Puccinia striiformis f.sp. tritici (Pst is a major constraint to wheat production worldwide. The molecular events that underlie Pst pathogenicity are largely unknown. Like all rusts, Pst creates a specialized cellular structure within host cells called the haustorium to obtain nutrients from wheat, and to secrete pathogenicity factors called effector proteins. We purified Pst haustoria and used next-generation sequencing platforms to assemble the haustorial transcriptome as well as the transcriptome of germinated spores. 12,282 transcripts were assembled from 454-pyrosequencing data and used as reference for digital gene expression analysis to compare the germinated uredinospores and haustoria transcriptomes based on Illumina RNAseq data. More than 400 genes encoding secreted proteins which constitute candidate effectors were identified from the haustorial transcriptome, with two thirds of these up-regulated in this tissue compared to germinated spores. RT-PCR analysis confirmed the expression patterns of 94 effector candidates. The analysis also revealed that spores rely mainly on stored energy reserves for growth and development, while haustoria take up host nutrients for massive energy production for biosynthetic pathways and the ultimate production of spores. Together, these studies substantially increase our knowledge of potential Pst effectors and provide new insights into the pathogenic strategies of this important organism.

  2. Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1.

    Science.gov (United States)

    Cooke, Sam F; Komorowski, Robert W; Kaplan, Eitan S; Gavornik, Jeffrey P; Bear, Mark F

    2015-02-01

    Familiarity with stimuli that bring neither reward nor punishment, manifested through behavioral habituation, enables organisms to detect novelty and devote cognition to important elements of the environment. Here we describe in mice a form of long-term behavioral habituation to visual grating stimuli that is selective for stimulus orientation. Orientation-selective habituation (OSH) can be observed both in exploratory behavior in an open arena and in a stereotyped motor response to visual stimuli in head-restrained mice. We found that the latter behavioral response, termed a 'vidget', requires V1. Parallel electrophysiological recordings in V1 revealed that plasticity, in the form of stimulus-selective response potentiation (SRP), occurred in layer 4 of V1 as OSH developed. Local manipulations of V1 that prevented and reversed electrophysiological modifications likewise prevented and reversed memory demonstrated behaviorally. These findings suggest that a form of long-term visual recognition memory is stored via synaptic plasticity in primary sensory cortex.

  3. Transmitter-receiver system

    NARCIS (Netherlands)

    De Weerdt, E.; Van Kampen, E.J.; Chu, Q.P.

    2009-01-01

    The invention relates to a transmitter-receiver system comprising at least three transmitters and at least a first receiver and a second receiver, wherein the receivers are connected to a computing device that is arranged to analyse signals that said receivers receive from said transmitters and to

  4. MAC-v1: A new global aerosol climatology for climate studies

    OpenAIRE

    Kinne, S.; O’Donnel, D.; Stier, P.; Kloster, S.; Zhang, K.; Schmidt, H.; Rast, S.; Giorgetta, M.; Eck, T.; Stevens, B.

    2013-01-01

    The Hamburg Aerosol Climatology version 1 (HAC-v1) is introduced. It describes the optical properties of tropospheric aerosols on monthly timescales and with global coverage at a spatial resolution of 1 degree in latitude and longitude. By providing aerosol radiative properties for any wavelength of the solar (or shortwave) and of the terrestrial (or longwave) radiation spectrum, as needed in radiative transfer applications, this HAC-v1 data-set lends itself to simplified and computationally ...

  5. Multinational Experiment 7: A Process for Deterring and Influencing Actors in Space, v1.01

    Science.gov (United States)

    2013-01-31

    UNCLASSIFIED Page 1 of 29 UNCLASSIFIED Version 1·01 A Process for Deterring and Influencing Actors in Space v1.01 31 Jan 2013...COVERED 4. TITLE AND SUBTITLE Multinational Experiment 7: Outcome 3: Space-A Process for Deterring and Influencing Actors in Space v1.01 31 Jan... PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) JOINT STAFF-MN//ACT Integration 116 Lakeview Parkway Suffolk, VA 23435 8. PERFORMING ORGANIZATION

  6. Effects of surround suppression on response adaptation of V1 neurons to visual stimuli

    OpenAIRE

    LI, Peng; JIN, Cai-Hong; JIANG, San; LI, Miao-Miao; WANG, Zi-Lu; ZHU, Hui; CHEN, Cui-Yun; HUA, Tian-Miao

    2014-01-01

    The influence of intracortical inhibition on the response adaptation of visual cortical neurons remains in debate. To clarify this issue, in the present study the influence of surround suppression evoked through the local inhibitory interneurons on the adaptation effects of neurons in the primary visual cortex (V1) were observed. Moreover, the adaptations of V1 neurons to both the high-contrast visual stimuli presented in the classical receptive field (CRF) and to the costimulation presented ...

  7. Single-molecule analysis of inhibitory pausing states of V1-ATPase.

    Science.gov (United States)

    Uner, Naciye Esma; Nishikawa, Yoshihiro; Okuno, Daichi; Nakano, Masahiro; Yokoyama, Ken; Noji, Hiroyuki

    2012-08-17

    V(1)-ATPase, the hydrophilic V-ATPase domain, is a rotary motor fueled by ATP hydrolysis. Here, we found that Thermus thermophilus V(1)-ATPase shows two types of inhibitory pauses interrupting continuous rotation: a short pause (SP, 4.2 s) that occurred frequently during rotation, and a long inhibitory pause (LP, >30 min) that terminated all active rotations. Both pauses occurred at the same angle for ATP binding and hydrolysis. Kinetic analysis revealed that the time constants of inactivation into and activation from the SP were too short to represent biochemically predicted ADP inhibition, suggesting that SP is a newly identified inhibitory state of V(1)-ATPase. The time constant of inactivation into LP was 17 min, consistent with one of the two time constants governing the inactivation process observed in bulk ATPase assay. When forcibly rotated in the forward direction, V(1) in LP resumed active rotation. Solution ADP suppressed the probability of mechanical activation, suggesting that mechanical rotation enhanced inhibitory ADP release. These features were highly consistent with mechanical activation of ADP-inhibited F(1), suggesting that LP represents the ADP-inhibited state of V(1)-ATPase. Mechanical activation largely depended on the direction and angular displacement of forced rotation, implying that V(1)-ATPase rotation modulates the off rate of ADP.

  8. Characterization of V1R receptor (ora) genes in Lake Victoria cichlids.

    Science.gov (United States)

    Ota, Tomoki; Nikaido, Masato; Suzuki, Hikoyu; Hagino-Yamagishi, Kimiko; Okada, Norihiro

    2012-05-15

    Although olfaction could play a crucial role in underwater habitats by allowing fish to sense a variety of nonvolatile chemical signals, the importance of olfaction in species-rich cichlids is still controversial. In particular, examining whether cichlids rely on olfaction for reproduction is of primary interest to understand the mechanisms of speciation. In the present study, we explored the V1R (also known as ora) genes, which are believed to encode reproductive pheromone receptors in fish, in the genomes of Lake Victoria cichlids. By screening a bacterial artificial chromosome library, we identified all six intact V1R genes (V1R1 to V1R6) that have been reported in other teleost fish. Furthermore, RT-PCR and in situ hybridization analyses showed that all of the V1R genes were expressed in the olfactory epithelium, indicating that these receptors are functional in cichlids. These observations indicate that cichlids use V1R-mediated olfaction in some ways for their social behaviors. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. METEOR v1.0 - Design and structure of the software package; METEOR v1.0 - Estructura y modulos informaticos

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, E.

    1994-07-01

    This script describes the structure and the separated modules of the software package METEOR for the statistical analysis of meteorological data series. It contains a systematic description of the subroutines of METEOR and, also, of the required shape for input and output files. The original version of METEOR have been developed by Ph.D. Elena Palomo, CIEMAT-IER, GIMASE. It is built by linking programs and routines written in FORTRAN 77 and it adds thc graphical capabilities of GNUPLOT. The shape of this toolbox was designed following the criteria of modularity, flexibility and agility criteria. All the input, output and analysis options are structured in three main menus: i) the first is aimed to evaluate the quality of the data set; ii) the second is aimed for pre-processing of the data; and iii) the third is aimed towards the statistical analyses and for creating the graphical outputs. Actually the information about METEOR is constituted by three documents written in spanish: 1) METEOR v1.0: User's guide; 2) METEOR v1.0: A usage example; 3) METEOR v 1.0: Design and structure of the software package. (Author)

  10. A New Estimate of the Power Emitted by Enceladus' Tiger Stripes

    Science.gov (United States)

    Spencer, John R.; Howett, C. J.; Verbiscer, A. J.; Hurford, T. A.; Segura, M.; Spencer, D. C.

    2013-10-01

    The heat flow from the south pole of Enceladus is a fundamental constraint on its tidal dissipation mechanisms, orbital evolution, and the physical processes that generate the plumes. Cassini Composite Infrared Spectrometer (CIRS) observations of the integrated 17 - 1000 micron thermal emission from the south pole have produced an estimated heat flow of 15.8 +/- 3.1 GW (Howett et al. 2011). This is a surprisingly high value, about 10x higher than can be generated by steady-state tidal heating (Meyer and Wisdom 2007). The estimate includes all sources of south polar endogenic emission, but is model-dependent because the observation also includes passive re-radiation of absorbed sunlight, which must be modeled and subtracted from the observed radiation. An alternate approach is to use higher spatial resolution CIRS observations in which emission from the tiger stripes, which is certainly endogenic, is spatially separated from emission from the surrounding terrain, which consists of passive emission plus a possible endogenic component. Tiger stripe emission is thus a lower bound on total endogenic emission, and is itself important as a constraint on plume generation and transport. CIRS has several observations of 9 - 16 micron emission with sufficient resolution to resolve the tiger stripes, but only limited resolved observations at longer wavelengths where most heat is radiated. Combining the best resolved data at all wavelengths, with reasonable assumptions about the ratio of long to short wavelength emission, we obtain preliminary estimates of tiger stripe thermal emission of roughly 4.2 GW, to which must be added ~0.5 GW of plume latent heat (Ingersoll and Pankine 2009), for a total tiger stripe power of about 4.7 GW. We are investigating whether the discrepancy between the new tiger stripe heat flow estimate, and the earlier estimate for the entire south pole, results from a large heat flow component that is not from the tiger stripes, or possible inaccuracies in

  11. Introgression of Chromosome 3Ns from Psathyrostachys huashanica into Wheat Specifying Resistance to Stripe Rust

    Science.gov (United States)

    Kang, Houyang; Wang, Yi; Fedak, George; Cao, Wenguang; Zhang, Haiqin; Fan, Xing; Sha, Lina; Xu, Lili; Zheng, Youliang; Zhou, Yonghong

    2011-01-01

    Wheat stripe rust is a destructive disease in the cool and humid wheat-growing areas of the world. Finding diverse sources of stripe rust resistance is critical for increasing genetic diversity of resistance for wheat breeding programs. Stripe rust resistance was identified in the alien species Psathyrostachys huashanica, and a wheat- P. huashanica amphiploid line (PHW-SA) with stripe rust resistance was reported previously. In this study, a P. huashanica 3Ns monosomic addition line (PW11) with superior resistance to stripe rust was developed, which was derived from the cross between PHW-SA and wheat J-11. We evaluated the alien introgressions PW11-2, PW11-5 and PW11-8 which were derived from line PW11 for reaction to new Pst race CYR32, and used molecular and cytogenetic tools to characterize these lines. The introgressions were remarkably resistant to CYR32, suggesting that the resistance to stripe rust of the introgressions thus was controlled by gene(s) located on P. huashanica chromosome 3Ns. All derived lines were cytologically stable in term of meiotic chromosome behavior. Two 3Ns chromosomes of P. huashanica were detected in the disomic addition line PW11-2. Chromosomes 1B of substitution line PW11-5 had been replaced by a pair of P. huashanica 3Ns chromosomes. In PW11-8, a small terminal segment from P. huashanica chromosome arm 3NsS was translocated to the terminal region of wheat chromosomes 3BL. Thus, this translocated chromosome is designated T3BL-3NsS. These conclusions were further confirmed by SSR analyses. Two 3Ns-specific markers Xgwm181 and Xgwm161 will be useful to rapidly identify and trace the translocated fragments. These introgressions, which had significant characteristics of resistance to stripe rust, could be utilized as novel germplasms for wheat breeding. PMID:21760909

  12. Meat quality of broiler breast fillets with white striping and woody breast muscle myopathies.

    Science.gov (United States)

    Tijare, V V; Yang, F L; Kuttappan, V A; Alvarado, C Z; Coon, C N; Owens, C M

    2016-09-01

    The global poultry industry has been faced with emerging broiler breast meat quality issues including conditions known as white striping (WS, white striations parallel to muscle fibers) and woody breast (WB, hardness of raw fillet). Experiments were conducted to evaluate effects of WS and WB hardness on meat quality traits in broiler breast fillets. In Exp. 1, birds were processed at approximately 9 wk of age and deboned at 4 h postmortem (PM); in Exp. 2, birds were processed at approximately 6 and 9 wk of age and deboned at 2 h PM. Fillets were categorized as: normal for both white striping and woody breast (NORM); moderate for white striping and mild for woody breast (MILD); severe for white striping and mild for woody breast (WS); severe for woody breast and moderate for white striping (WB); or severe for both white striping and woody breast (BOTH). Sarcomere length, gravimetric fragmentation index, marination uptake, cook loss, and Meullenet-Owens razor shear energy (MORSE) values on non-marinated and marinated fillets were assessed. Sarcomeres tended to be longer (P = 0.07) with increasing severity of WS and WB in both experiments and gravimetric fragmentation index did not differ (P > 0.05) among categories. Marinade uptake decreased (P  0.05) in non-marinated fillets, the marinated BOTH fillets had greater MORSE values (P  0.05) among categories of marinated breasts. At 9 wk, WS and BOTH were higher (P white striping and woody breast, individually or in combination, negatively impact meat quality, especially water holding capacity attributes such as marinade uptake and cook loss. © 2016 Poultry Science Association Inc.

  13. Vasotocin neurons and septal V1a-like receptors potently modulate songbird flocking and responses to novelty.

    Science.gov (United States)

    Kelly, Aubrey M; Kingsbury, Marcy A; Hoffbuhr, Kristin; Schrock, Sara E; Waxman, Brandon; Kabelik, David; Thompson, Richmond R; Goodson, James L

    2011-06-01

    Previous comparisons of territorial and gregarious finches (family Estrildidae) suggest the hypothesis that arginine vasotocin (VT) neurons in the medial bed nucleus of the stria terminalis (BSTm) and V(1a)-like receptors in the lateral septum (LS) promote flocking behavior. Consistent with this hypothesis, we now show that intraseptal infusions of a V(1a) antagonist in male zebra finches (Taeniopygia guttata) reduce gregariousness (preference for a group of 10 versus 2 conspecific males), but have no effect on the amount of time that subjects spend in close proximity to other birds ("contact time"). The antagonist also produces a profound increase in anxiety-like behavior, as exhibited by an increased latency to feed in a novelty-suppressed feeding test. Bilateral knockdown of VT production in the BSTm using LNA-modified antisense oligonucleotides likewise produces increases in anxiety-like behavior and a potent reduction in gregariousness, relative to subjects receiving scrambled oligonucleotides. The antisense oligonucleotides also produced a modest increase in contact time, irrespective of group size. Together, these combined experiments provide clear evidence that endogenous VT promotes preferences for larger flock sizes, and does so in a manner that is coupled to general anxiolysis. Given that homologous peptide circuitry of the BSTm-LS is found across all tetrapod vertebrate classes, these findings may be predictive for other highly gregarious species. Published by Elsevier Inc.

  14. Learning Enhances Sensory Processing in Mouse V1 before Improving Behavior.

    Science.gov (United States)

    Jurjut, Ovidiu; Georgieva, Petya; Busse, Laura; Katzner, Steffen

    2017-07-05

    A fundamental property of visual cortex is to enhance the representation of those stimuli that are relevant for behavior, but it remains poorly understood how such enhanced representations arise during learning. Using classical conditioning in adult mice of either sex, we show that orientation discrimination is learned in a sequence of distinct behavioral stages, in which animals first rely on stimulus appearance before exploiting its orientation to guide behavior. After confirming that orientation discrimination under classical conditioning requires primary visual cortex (V1), we measured, during learning, response properties of V1 neurons. Learning improved neural discriminability, sharpened orientation tuning, and led to higher contrast sensitivity. Remarkably, these learning-related improvements in the V1 representation were fully expressed before successful orientation discrimination was evident in the animals' behavior. We propose that V1 plays a key role early in discrimination learning to enhance behaviorally relevant sensory information. SIGNIFICANCE STATEMENT Decades of research have documented that responses of neurons in visual cortex can reflect the behavioral relevance of visual information. The behavioral relevance of any stimulus needs to be learned, though, and little is known how visual sensory processing changes, as the significance of a stimulus becomes clear. Here, we trained mice to discriminate two visual stimuli, precisely quantified when learning happened, and measured, during learning, the neural representation of these stimuli in V1. We observed learning-related improvements in V1 processing, which were fully expressed before discrimination was evident in the animals' behavior. These findings indicate that sensory and behavioral improvements can follow different time courses and point toward a key role of V1 at early stages in discrimination learning. Copyright © 2017 the authors 0270-6474/17/376460-15$15.00/0.

  15. WISE-Selected Red and Obscured Quasars in Stripe 82

    Science.gov (United States)

    Glikman, Eilat; Lacy, M.; Urrutia, T.; Urry, C. M.

    2013-01-01

    We identified a sample of 120 dust-reddened quasars identified by matching radio sources detected at 1.4 GHz in the Faint Images of the Radio Sky at Twenty Centimeters (FIRST) survey with the near-infrared Two Micron All Sky Survey (2MASS) catalog and color-selecting red sources. We interpret this population of objects as a tansitional phase in merger-driven quasar/galaxy co-evolution where these reddened quasars are shedding their dusty environment prior to becoming a “normal” blue quasar. When correcting for extinction, we find that red quasars make up ~15%-20% of the luminous quasar population. The radio requirement was intended to avoid contamination from stars, but restricts our sample to radio-detected objects. With the release of the Wide-Field Infrared Survey Explorer (WISE) we can now select all red quasars regardless of their radio propoerties, using infrared colors. We present a pilot survey for heavily obscured luminous quasars using infrared selection from WISE colors in the SDSS Stripe 82. We concentrated on objects with both bright WISE 22 micron fluxes and 2MASS magnitudes that lack spectra in SDSS to identify the brightest (mostly high luminosity) sources that complement the fainter objects in Spitzer-selected samples. Our relatively liberal color selection produced a candidate list of 12 sources. We obtained near-infrared spectra for all using SpeX on IRTF and have spectroscopically confirmed at least five obscured and reddened quasars. We explore the nature of the dusty quasar population and how it depends on redshift, luminosity and radio-loudness.

  16. BASALIT trial: double-blind placebo-controlled allergen immunotherapy with rBet v 1-FV in birch-related soya allergy.

    Science.gov (United States)

    Treudler, R; Franke, A; Schmiedeknecht, A; Ballmer-Weber, B; Worm, M; Werfel, T; Jappe, U; Biedermann, T; Schmitt, J; Brehler, R; Kleinheinz, A; Kleine-Tebbe, J; Brüning, H; Ruëff, F; Ring, J; Saloga, J; Schäkel, K; Holzhauser, T; Vieths, S; Simon, J C

    2017-08-01

    Conflicting results exist on the effect of allergen immunotherapy (AIT) on pollen-related food allergy. We aimed to investigate the efficacy of one-year AIT with the folding variant (FV) of recombinant (r) Bet v 1 on birch-related soya allergy. Of 138 subjects with Bet v 1 sensitization, 82 were positive at double-blind placebo-controlled food challenge (DBPCFC) with soya. A total of 56 of 82 were randomized in the ratio of 2:1 (active: placebo). Per-protocol population (PPP) had received ≥150 μg of allergen or placebo preparation. lowest observed adverse effect levels (LOAEL), postinterventional occurrence of objective signs (objS) at any dose level, sIgE/IgG4 against Bet v 1 and Gly m 4. Between-group changes were investigated (ancova, Mann-Whitney U-test, Fisher exact test). Baseline characteristics including LOAELs were comparable in both groups with objS and subjS occurring in 82% and 95% of active (n = 38) vs 78% and 83% of placebo group (n = 18). After AIT, objS occurred in 24% and 47%, respectively. LOAEL group differences showed a beneficial tendency (P = 0.081) for LOAEL objective in PPP (30 active, 15 placebo). sIgG4 raised only in active group (Bet v 1: P = 0.054, Gly m 4: P = 0.037), and no relevant changes occurred for sIgE. Only 56% of the intended sample size was recruited. For the first time, we present data on the effect of rBet v 1-FV on birch-related soya allergy. rBet v 1-FV AIT induced significant immunogenic effects. Clinical assessment showed a tendency in favour of the active group but did not reach statistical significance. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. Zero-bias-field microwave dynamic magnetic properties in trapezoidal ferromagnetic stripe

    International Nuclear Information System (INIS)

    Bi, Mei; Wang, Xin; Lu, Haipeng; Zhang, Li; Deng, Longjiang; Xie, Jianliang

    2016-01-01

    Dynamic magnetization response of the axially magnetized ferromagnetic stripe with trapezoidal cross section has been studied. The stripe with beveled edges exhibits multiple resonant peaks modes under an in-plane microwave excitation compared with the single resonant of vertical edge surfaces. The complexity of the observed response is attributed to the spatially nonuniform equilibrium spin distribution at the stripe edges. Micromagnetic simulations identify spin waves as spatially localized mode at the modified edges. This one is also described by effective pinning boundary conditions taking into account finite-size effects, which is related to the exchange interaction, surface anisotropy and dipole–dipole interaction. These results provide detailed insights into the nonlinear spin dynamics of microstructures influenced by the edge properties. - Highlights: • Series of FeCoNbBCu stripes with trapezoidal cross section have been fabricated. • The stripe with beveled edges exhibits multiple resonant peaks modes. • Micromagnetic simulations identify the spatially localized mode. • The effective pinning boundary conditions taking into account finite-size effects.

  18. Development of a Spectrophotometric System to Detect White Striping Physiopathy in Whole Chicken Carcasses

    Science.gov (United States)

    Traffano-Schiffo, Maria Victoria; Castro-Giraldez, Marta; Colom, Ricardo J.; Fito, Pedro J.

    2017-01-01

    Due to the high intensification of poultry production in recent years, white chicken breast striping is one of the most frequently seen myopathies. The aim of this research was to develop a spectrophotometry-based sensor to detect white striping physiopathy in chicken breast meat in whole chicken carcasses with skin. Experiments were carried out using normal and white striping breasts. In order to understand the mechanism involved in this physiopathy, the different tissues that conform each breast were analyzed. Permittivity in radiofrequency (40 Hz to 1 MHz) was measured using two different sensors; a sensor with two flat plates to analyze the whole breast with skin (NB or WSB), and a two needles with blunt-ended sensor to analyze the different surface tissues of the skinless breast. In the microwave range (500 MHz to 20 GHz), permittivity was measured as just was described for the two needles with blunt-ended sensor. Moreover, fatty acids composition was determined by calorimetry techniques from −40 °C to 50 °C at 5 °C/min after previously freeze-drying the samples, and pH, microstructure by Cryo-SEM and binocular loupe structure were also analyzed. The results showed that the white striping physiopathy consists of the partial breakdown of the pectoral muscle causing an increase in fatty acids, reducing the quality of the meat. It was possible to detect white striping physiopathy in chicken carcasses with skin using spectrophotometry of radiofrequency spectra. PMID:28471378

  19. Bet v 1 homologues in strawberry identified as IgE-binding proteins and presumptive allergens.

    Science.gov (United States)

    Karlsson, A L; Alm, R; Ekstrand, B; Fjelkner-Modig, S; Schiött, A; Bengtsson, U; Björk, L; Hjernø, K; Roepstorff, P; Emanuelsson, C S

    2004-12-01

    No strawberry allergen has so far been identified and characterized. Serum samples were collected from patients with a suggestive case history of adverse reactions to strawberry and other fruits. Extracts from fresh and frozen strawberries were analysed by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), Western blotting and mass spectrometry. Patient blood samples were analysed for inhibition of IgE binding and basophil degranulation. Several IgE-binding proteins could be detected. In more than half of the patient sera, a 20/18-kDa doublet band was observed in Western blotting. These two bands were excised and analysed by mass spectrometry showing the presence of proteins belonging to the Bet v 1 family of allergens. Inhibition of the IgE binding to the 20/18-kDa doublet was obtained by addition of two recombinantly expressed allergens belonging to the Bet v 1 family (Bet v 1 and Mal d 1) and strawberry protein extract. In a cell-based assay of patient blood samples, basophil degranulation could be induced by strawberry protein extract and by Bet v 1 and Mal d 1. We conclude that strawberry homologues to Bet v 1 may be allergens of importance for adverse reactions to strawberry.

  20. Effects of surround suppression on response adaptation of V1 neurons to visual stimuli.

    Science.gov (United States)

    Li, Peng; Jin, Cai-Hong; Jiang, San; Li, Miao-Miao; Wang, Zi-Lu; Zhu, Hui; Chen, Cui-Yun; Hua, Tian-Miao

    2014-09-01

    The influence of intracortical inhibition on the response adaptation of visual cortical neurons remains in debate. To clarify this issue, in the present study the influence of surround suppression evoked through the local inhibitory interneurons on the adaptation effects of neurons in the primary visual cortex (V1) were observed. Moreover, the adaptations of V1 neurons to both the high-contrast visual stimuli presented in the classical receptive field (CRF) and to the costimulation presented in the CRF and the surrounding nonclassical receptive field (nCRF) were compared. The intensities of surround suppression were modulated with different sized grating stimuli. The results showed that the response adaptation of V1 neurons decreased significantly with the increase of surround suppression and this adaptation decrease was due to the reduction of the initial response of V1 neurons to visual stimuli. However, the plateau response during adaptation showed no significant changes. These findings indicate that the adaptation effects of V1 neurons may not be directly affected by surround suppression, but may be dynamically regulated by a negative feedback network and be finely adjusted by its initial spiking response to stimulus. This adaptive regulation is not only energy efficient for the central nervous system, but also beneficially acts to maintain the homeostasis of neuronal response to long-presenting visual signals.

  1. Receiver Test Selection Criteria

    Science.gov (United States)

    2015-03-12

    The DOT requests that GPS manufacturers submit receivers for test in the following TWG categories: - Aviation (non-certified), cellular, general location/navigation, high precision, timing, networks, and space-based receivers - Each receiver should b...

  2. Reactions of sulphur mustard and sarin on V 1.02 O 2.98 nanotubes.

    Science.gov (United States)

    Mahato, T H; Prasad, G K; Singh, Beer; Srivastava, A R; Ganesan, K; Acharya, J; Vijayaraghavan, R

    2009-07-30

    Reactions of sulphur mustard and sarin were studied on the surface of V(1.02)O(2.98) nanotubes by gas chromatography and gas chromatography-mass spectrometry techniques. The V(1.02)O(2.98) nanotube samples were made by using hydrothermal method and characterized by scanning electron microscopy, nitrogen adsorption, X-ray diffractometry and thermogravimetry. Later, they were exposed to sulphur mustard and sarin separately at ambient temperature (30+/-2 degrees C). The data explored the formation of sulphoxide of sulphur mustard, thiodiglycol for sulphur mustard and isopropyl methyl phosphonic acid for sarin on V(1.02)O(2.98) nanotubes illustrating the role of oxidation and hydrolysis reactions in the decontamination.

  3. Inhibition of human Na(v)1.5 sodium channels by strychnine and its analogs.

    Science.gov (United States)

    Yuan, Chunhua; Sun, Lirong; Zhang, Meng; Li, Shuji; Wang, Xuemin; Gao, Tianming; Zhu, Xinhong

    2011-08-15

    Strychnine and brucine from the seeds of the plant Strychnos nux vomica have been shown to have interesting pharmacological effects on several neurotransmitter receptors. In this study, we have characterized the pharmacological properties of strychnine and its analogs on human Na(v)1.5 channels to assess their potential therapeutic advantage in certain arrhythmias. Among the eight alkaloids, only strychnine and icajine exhibited inhibition potency on the Na(v)1.5 channel with the half-maximum inhibition (IC(50)) values of 83.1μM and 104.6μM, respectively. Structure-function analysis indicated that the increased bulky methoxy groups on the phenyl ring or the negatively charged oxygen atom may account for this lack of inhibition on the Na(v)1.5 channel. Strychnine and icajine may bind to the channel by cation-π interactions. The substitution with a large side chain on the phenyl ring or the increased molecular volume may alter the optimized position for the compound close to the binding sites of the channel. Strychnine and icajine bind to the Na(v)1.5 channel with a new mechanism that is different from TTX and local anesthetics. They bind to the outer vestibule of the channel pore with fast association and dissociation rates at resting state. Strychnine and icajine had little effect on steady-state fast inactivation but markedly shifted the slow inactivation of Na(v)1.5 currents toward more hyperpolarized potentials. The property of icajine influencing slow-inactivated state of Na(v)1.5 channel would be potential therapeutic advantages in certain arrhythmias. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Identification of Bet v 1-related allergens in fig and other Moraceae fruits.

    Science.gov (United States)

    Hemmer, W; Focke, M; Marzban, G; Swoboda, I; Jarisch, R; Laimer, M

    2010-04-01

    Allergy to fig fruit (Ficus carica) has been described in patients allergic to Ficus benjamina or rubber latex but may occur also in pollen-allergic patients. To study the potential cross-reactivity between fig and taxonomically related fruits with the major birch pollen allergen Bet v 1. One hundred and eighty-eight patients with or without birch pollen allergy were prick-to-prick tested with fig (F. carica), mulberry (Morus alba), jackfruit (Artocarpus heterophyllus; all family Moraceae) and other pollen-associated foods. Moraceae fruit extracts were separated by SDS-PAGE and tested with patient sera and polyclonal antisera against Mal d 1. Western blot inhibition was performed with Moraceae fruit extracts, birch pollen and recombinant Bet v 1. Putative Bet v 1 homologs in Moraceae fruits were analysed by liquid chromatography-ion trap mass spectrometry. Among 85 patients with isolated birch pollen allergy, 78% had a positive skin test to fresh fig, 10% to dried fig, 91% to mulberry, 91% to jackfruit, 77% to Rosaceae fruits and 83% to hazelnut. Sixty-six per cent of birch pollen-allergic patients positive for fig, reported symptoms after consumption of fresh figs, whereas dried figs were mostly well tolerated. In 60 patients with isolated Ficus benjamina sensitization, the reactivity rates to the same foods were 83-40-0-0-0-0%. None of 32 mugwort pollen-allergic patients reacted to Moraceae fruits. Rabbit anti-Mal d 1 and patient sera reacted to a 17 kDa band in all Moraceae extracts. IgE binding to these proteins was completely inhibited by birch pollen and rBet v 1. Mass spectrometry identified several peptides from the 17 kDa fig, mulberry and jackfruit allergen with respectively 60%, 56% and 76% homology to Bet v 1. Fig and other Moraceae fruits contain allergens homologous to Bet v 1 and represent clinically relevant birch pollen-associated foods.

  5. Charged Stripes in the Two-Orbital Hubbard Model for Pnictides

    Science.gov (United States)

    Yao, Dao-Xin; Luo, Qinlong; Prestel, Thomas; Daghofer, Maria; Moreo, Adriana; Dagotto, Elbio

    2011-03-01

    The two-orbital Hubbard model for the pnictides is studied numerically in the real-space Hartree-Fock approximation. Upon electron doping, states with a nonuniform ditribution of charge are stabilized. The patterns observed correspond to charge stripes that run perpendicular to the direction of the spin stripes of the undoped magnetic ground state. These striped states are robust when the undoped state has a gap, although with a decreasing amplitude as the gap decreases. Results for hole doping and implications for recent experiments that reported electronic nematic states and spin incommensurability in the pnictides are also discussed. This work was supported by the U.S. Department of Energy, Office of Basic Energy Sciences, Materials Sciences and Engineering Division (Q.L., A.M., E.D.), the SYSU and NSFC-11074310 (D.X.Y.), the DFG under the Emmy-Noether program (T.P., M.D.).

  6. Lump Solutions and Resonance Stripe Solitons to the (2+1-Dimensional Sawada-Kotera Equation

    Directory of Open Access Journals (Sweden)

    Xian Li

    2017-01-01

    Full Text Available Based on the symbolic computation, a class of lump solutions to the (2+1-dimensional Sawada-Kotera (2DSK equation is obtained through making use of its Hirota bilinear form and one positive quadratic function. These solutions contain six parameters, four of which satisfy two determinant conditions to guarantee the analyticity and rational localization of the solutions, while the others are free. Then by adding an exponential function into the original positive quadratic function, the interaction solutions between lump solutions and one stripe soliton are derived. Furthermore, by extending this method to a general combination of positive quadratic function and hyperbolic function, the interaction solutions between lump solutions and a pair of resonance stripe solitons are provided. Some figures are given to demonstrate the dynamical properties of the lump solutions, interaction solutions between lump solutions, and stripe solitons by choosing some special parameters.

  7. Influence of substrate on the magnetic properties of Ni and permalloy sub-micrometric patterned stripes

    Energy Technology Data Exchange (ETDEWEB)

    Duque, J G S [Nucleo de Fisica, UFS, 49500-000, Itabaiana, SE (Brazil); Rosa, W O [CSIC, Instituto de Ciencia de Materiales, 28049 Madrid (Spain); Nunes, W C [Instituto de Fisica, UFF, Campus da Praia Vermelha, Niteroi, RJ 24.210-340 (Brazil); De Araujo, A E P [Unidade Academica de Garanhuns, UFRPE, CEP 55296-190, Garanhuns-PE (Brazil); Pagliuso, P G; Cescato, L; Knobel, M [Instituto de Fisica ' Gleb Wataghin' , UNICAMP, CP 6165, Campinas SP (Brazil); Socolovsky, L M [UFG, Instituto de Fisica, BR-74001970 Goiania, GO (Brazil); Zysler, R D, E-mail: jduque@fisica.ufs.b [Centro Atomico Bariloche, 8400 San Carlos de Bariloche, RN (Argentina)

    2010-01-20

    The magnetic properties of sub-micrometric magnetic structures of Ni and permalloy (Ni{sub 80}Fe{sub 20}) patterned stripes are studied as functions of temperature. The samples are produced by combining an interferometric lithographic technique with sputtering. At room temperature, ferromagnetic resonance and hysteresis data indicate the existence of an in-plane uniaxial anisotropy in both samples. The NiFe sample has an easy axis along the stripes direction in the entire studied temperature range (2 < T < 300 K). On the other hand, an interesting change in the easy magnetization direction is observed in Ni samples, from parallel to perpendicular to the axis of the stripes, when the temperature is decreased. The results are interpreted in terms of a competition between shape and magnetoelastic anisotropies.

  8. A new species of striped Ichthyophis Fitzinger, 1826 (Amphibia: Gymnophiona: Ichthyophiidae) from Myanmar.

    Science.gov (United States)

    Wilkinson, Mark; Presswell, Bronwen; Sherratt, Emma; Papadopoulou, Anna; Gower, David J

    2014-04-02

    A new species of striped ichthyophiid caecilian, Ichthyophis multicolor sp. nov., is described on the basis of morphological and molecular data from a sample of 14 specimens from Ayeyarwady Region, Myanmar. The new species resembles superficially the Indian I. tricolor Annandale, 1909 in having both a pale lateral stripe and an adjacent dark ventrolateral stripe contrasting with a paler venter. It differs from I. tricolor in having many more annuli, and in many details of cranial osteology, and molecular data indicate that it is more closely related to other Southeast Asian Ichthyophis than to those of South Asia. The caecilian fauna of Myanmar is exceptionally poorly known but is likely to include chikilids as well as multiple species of Ichthyophis.

  9. Striped states in a many-body system of tilted dipoles

    Science.gov (United States)

    Wenzel, Matthias; Böttcher, Fabian; Langen, Tim; Ferrier-Barbut, Igor; Pfau, Tilman

    2017-11-01

    We study theoretically and experimentally the behavior of a strongly confined dipolar Bose-Einstein condensate in the regime of quantum-mechanical stabilization by beyond-mean-field effects. Theoretically, we demonstrate that self-organized "striped" ground states are predicted in the framework of the extended Gross-Pitaevskii theory. Experimentally, by tilting the magnetic dipoles we show that self-organized striped states can be generated, likely in their metastable state. Matter-wave interference experiments with multiple stripes show that there is no long-range off-diagonal order (global phase coherence). We outline a parameter range where global phase coherence could be established, thus paving the way towards the observation of supersolid states in this system.

  10. Operating principles of rotary molecular motors: differences between F1and V1motors.

    Science.gov (United States)

    Yamato, Ichiro; Kakinuma, Yoshimi; Murata, Takeshi

    2016-01-01

    Among the many types of bioenergy-transducing machineries, F- and V-ATPases are unique bio- and nano-molecular rotary motors. The rotational catalysis of F 1 -ATPase has been investigated in detail, and molecular mechanisms have been proposed based on the crystal structures of the complex and on extensive single-molecule rotational observations. Recently, we obtained crystal structures of bacterial V 1 -ATPase (A 3 B 3 and A 3 B 3 DF complexes) in the presence and absence of nucleotides. Based on these new structures, we present a novel model for the rotational catalysis mechanism of V 1 -ATPase, which is different from that of F 1 -ATPases.

  11. Effect of white striping on chemical composition and nutritional value of chicken breast meat

    Directory of Open Access Journals (Sweden)

    Massimiliano Petracci

    2014-03-01

    Full Text Available White striping defect (appearance of white striations parallel to muscle fiber on surface of breast is considered an emerging issue in chicken breast meat which is related to increasing growth rate of modern hybrid birds. This study was aimed at evaluating the effect of white striping on chemical composition and nutritional value of chicken breast meat. During three replications, a total of 108 Pectoralis major muscles representing three degrees of white striping (absence=normal; presence classified in 2 levels as moderate or severe were selected to determine proximate composition (moisture, protein, lipid and collagen as well as sarcoplasmic and myofibrillar protein profile by sodium dodecyl sulphatepolyacrylamide gel electrophoresis analysis. The results showed that both severe and moderate white-striped fillets had higher fat content (2.53 vs 1.46 vs 0.78%; P<0.001, lower protein level (20.9 vs 22.2 vs 22.9%; P<0.001, decreased quality of protein as proven by higher collagen content (1.30 vs 1.37 vs 1.43%; P<0.001, and different pattern on myofibrillar and sarcoplasmic fractions when compared to normal fillets. Moreover, severe white-striped fillets exhibited higher energy content (450.7 vs 421.1 kJ/100g; P<0.01 with respect to normal meat. In conclusion, there was a large worsening of nutritional value of chicken breast meat following occurrence of white striping and this might impair consumer attitude towards poultry meat.

  12. Determination of the quality of stripe-marked and cracked eggs during storage

    Directory of Open Access Journals (Sweden)

    Yu Chi Liu

    2017-07-01

    Full Text Available Objective Stripe marks, which occasionally occur on the shell, do not cause breakage to the shell and shell membranes of eggs. This study investigated the quality of intact eggs (IEs, minor stripe-marked eggs (MEs, severe stripe-marked eggs (SEs, and cracked eggs (CEs during 3-week storage at 25°C. Methods Shell eggs were collected the day after being laid and were washed. Among them, eggs without any visual cracks or stripe marks on the shells were evaluated as IEs by the plant employees using candling in a darkened egg storage room; the remaining eggs exhibited some eggshell defects. At day 3, the eggs were further categorized into IEs, MEs, SEs, CEs, and broken eggs (BEs on the basis of the description given. Except BEs, which were discarded, the remaining eggs were stored at 25°C (approximate relative humidity 50% and then analyzed. Results Stripe marks were observed primarily within the first 3 days after washing. At day 3, CEs had significantly (p<0.05 lower Haugh unit values, but all eggs had grades AA or A, according to the United States Department of Agriculture standard. As storage time increased, differences in egg quality between groups were more obvious. IEs had the highest eggshell breaking strength. During storage, the total plate counts and pathogens, namely Escherichia coli, Campylobacter spp., Staphylococcus aureus, and Salmonella spp., were not detectable in the internal content of IEs and SEs. Conclusion In conclusion, cracks degraded egg quality severely and minor stripe marks only slightly influenced the egg quality.

  13. Effect of white striping on turkey breast meat quality.

    Science.gov (United States)

    Soglia, F; Baldi, G; Laghi, L; Mudalal, S; Cavani, C; Petracci, M

    2018-01-08

    In the past decades, the intense selection practices carried out in order to develop fast growing and high breast-yield turkey hybrids profoundly modified the muscle physiology leading to the development of growth-related alterations and muscular abnormalities. White striations of variable thickness have been particularly observed on the ventral surface of Pectoralis major muscle belonging from heavy male turkeys since several years. However, although the effects of white striping (WS) have been extensively studied on broilers, this condition was not considered as a main quality issue by both turkey producers and meat industry. Thus, this study aimed at evaluating whether the occurrence of WS in heavy male turkeys affects the quality traits and technological properties of meat to the same extent previously observed for broilers. In two replications, 72 Pectoralis major muscles were classified as: normal (NORM), moderate WS (MOD) and severe WS (SEV) cases. The whole muscle was weighed and cut in order to assess colour, ultimate pH, water holding (drip and cooking losses) and binding (marinade uptake) capacities, NMR relaxation properties, shear force as well as proximate composition of meat. The Pectoralis major muscles affected by WS (both moderate and severe cases) exhibited a one-fifth increased weight in comparison with their NORM counterpart. However, the occurrence of WS only partially affected the proximate composition of the meat. In detail, although moisture, collagen and protein contents did not differ among the groups, if compared with NORM, higher lipid levels were found in SEV muscles, whereas MOD had intermediate values. On the other hand, both MOD and SEV exhibited lower ash content. Despite these variations in proximate composition, both water holding and binding capacities of turkey breast meat were not affected by WS. Indeed, quality traits of raw (pH, colour, cooking losses and shear force) and marinated (uptake, cooking losses and shear force

  14. Discrete modes of a ferromagnetic stripe dipolarly coupled to a ferromagnetic film: a Brillouin light scattering study

    International Nuclear Information System (INIS)

    Gubbiotti, G; Tacchi, S; Carlotti, G; Ono, T; Roussigne, Y; Tiberkevich, V S; Slavin, A N

    2007-01-01

    Spin wave excitations in a magnetic structure consisting of a series of long permalloy stripes of a rectangular cross section magnetized along the stripe length and situated above a continuous permalloy film are studied both experimentally and theoretically. Stripes and continuous film are coupled by dipole-dipole interaction across 10 nm thick Cu spacers. Experimental measurements made using the Brillouin light scattering technique (with the light wavevector oriented along the stripe width) provide evidence for one dispersive spin wave mode associated with the continuous film and several discrete non-dispersive modes resonating within the finite width of the stripes. To interpret the experimental spectra, an analytic theory based on the spin wave formalism for finite-width magnetic stripes has been developed, achieving a good qualitative and partly quantitative description of the experimentally observed spin wave spectrum of the system. In particular, it is explained why the presence of a continuous magnetic film near the magnetic stripe leads to a substantial decrease of the frequencies of the discrete dipolar spin wave modes localized within the stripes. A more quantitative description of the measured frequencies and of the spatial profiles of the spin wave eigenmodes has been obtained by numerical calculations performed using a finite element method

  15. Checkerboard local density of states in striped domains pinned by vortices

    DEFF Research Database (Denmark)

    Andersen, B.M.; Hedegård, P.; Bruus, Henrik

    2003-01-01

    We discuss recent elastic neutron scattering and scanning tunneling experiments on high-T-c cuprates exposed to an applied magnetic field. Antiferromagnetic vortex cores operating as pinning centers for surrounding stripes is qualitatively consistent with the neutron data provided the stripes have...... the antiphase modulation. Within a Green's function formalism we study the low energy electronic structure around the vortices and find that besides the dispersive quantum interference there exists a non-dispersive checkerboard interference pattern consistent with recent scanning tunneling measurements. Thus...

  16. Magnetic anisotropy of two-dimensional nanostructures: Transition-metal triangular stripes

    International Nuclear Information System (INIS)

    Dorantes-Davila, J.; Villasenor-Gonzalez, P.; Pastor, G.M.

    2005-01-01

    The magnetic anisotropy energy (MAE) of one-dimensional stripes having infinite length and triangular lateral structure are investigated in the framework of a self-consistent tight-binding method. One observes discontinuous changes in the easy magnetization direction along the crossover from one to two dimensions. The MAE oscillates as a function of stripe width and depends strongly on the considered transition metal (TM). The MAE of the two-leg ladder is strongly reduced as compared to that of the monoatomic chain and the convergence to the two-dimensional limit is rather slow

  17. Magnetic anisotropy of two-dimensional nanostructures: Transition-metal triangular stripes

    Energy Technology Data Exchange (ETDEWEB)

    Dorantes-Davila, J. [Instituto de Fisica, Universidad Autonoma de San Luis Potosi, San Luis Potosi (Mexico)]. E-mail: jdd@ifisica.uaslp.mx; Villasenor-Gonzalez, P. [Instituto de Fisica, Universidad Autonoma de San Luis Potosi, San Luis Potosi (Mexico); Pastor, G.M. [Laboratoire de Physique Quantique, Centre National de la Recherche Scientifique, Universite Paul Sabatier, Toulouse (France)

    2005-07-15

    The magnetic anisotropy energy (MAE) of one-dimensional stripes having infinite length and triangular lateral structure are investigated in the framework of a self-consistent tight-binding method. One observes discontinuous changes in the easy magnetization direction along the crossover from one to two dimensions. The MAE oscillates as a function of stripe width and depends strongly on the considered transition metal (TM). The MAE of the two-leg ladder is strongly reduced as compared to that of the monoatomic chain and the convergence to the two-dimensional limit is rather slow.

  18. Feshbach shape resonance for high Tc pairing in superlattices of quantum stripes and quantum wells

    Directory of Open Access Journals (Sweden)

    A Bianconi

    2006-09-01

    Full Text Available   The Feshbach shape resonances in the interband pairing in superconducting superlattices of quantum wells or quantum stripes is shown to provide the mechanism for high Tc superconductivity. This mechanism provides the Tc amplification driven by the architecture of material: superlattices of quantum wells (intercalated graphite or diborides and superlattices of quantum stripes (doped high Tc cuprate perovskites where the chemical potential is tuned to a Van Hove-Lifshitz singularity (vHs in the electronic energy spectrum of the superlattice associated with the change of the Fermi surface dimensionality in one of the subbands.

  19. Partial resistance to stripe rust and its effect on sustainability of wheat yield

    International Nuclear Information System (INIS)

    Qamar, M.; Din, R.U.; Gardazi, D.A.

    2014-01-01

    Stripe rust (Puccinia striiformis Westend. f. sp. tritici) poses a serious threat to wheat production in cooler areas of Pakistan. The 70% area of wheat in Pakistan is prone to stripe rust disease. It can cause 10-17% yield losses if susceptible cultivars are planted under favorable conditions. Level of partial plant resistance in bread wheat and its impact on sustainable wheat production was studied at the National Agricultural Research Centre, Islamabad under natural conditions in the field. Eleven Pakistani commercial wheat cultivars/advance lines including check (Inqalab 91) were assessed for the level of partial resistance against stripe rust using Area Under the Disease Progress Curve (AUDPC), disease severity (DS) and epidemic growth rate in comparison with wheat cultivar, Inqalab 91. During 2007 cropping season, natural epidemic was developed and relative AUDPC was recorded from 0 to 100% whereas the 2008 cropping season was dry and no stripe rust appeared. Two advanced lines (NR 268 and NR 285) showed the infection type (IT) less than 7 (incompatible reaction) to the mixture of prevailing stripe rust inoculums. Very low level of DS and AUDPC were recorded in the remaining cultivars/lines indicating a high level of partial resistance to stripe rust compared to the susceptible check cultivar, Inqalab 91. Among eight cultivars/lines that showed compatible type of reaction (IT greater then equal to 7), one was resistant (relative AUDPC = 20% of Inqalab 91) and six showed very high resistance levels (relative AUDPC greater then equal to 5%). Maximum level of resistance (relative AUDPC = 0.1%) was observed in advanced line, NR 271. The wheat cultivars/lines that showed a slow disease development (low DS and AUDPC), could be considered as -1 partially resistant for stripe rust infection. The yield (2178 kg ha) of susceptible check cultivar Inqalab-91 during 2007 was reduced to 45% as -1 compared to its yield (3945 kg ha) in epidemic free year (2008). Thus the use

  20. Evaluation of thermal striping risks: Limitation of cracks initiation and propagation

    International Nuclear Information System (INIS)

    Drubay, B.; Acker, D.

    1994-01-01

    Thermal striping is the effect of a rapid random oscillation of surface temperature inducing a corresponding fluctuation of surface strains. It occurs on components situated in the mixing zone of coolant streams of different temperatures and is characterised by large numbers of strain cycles having the potential to add to the fatigue damage produced by strain cycles associated with all other plant operating events. The purpose of this paper is to describe the R and D works performed in the frame of the European Fast Reactor project between 1985 and 1992 on the thermal striping: experimental works and validation of assessment methodology. (author)

  1. Sonographic anatomy of the newborn hip and high-resolution US equipments: internal capsular stripe and perichondral gap

    International Nuclear Information System (INIS)

    Ortore, P.; Fodor, G.; Psenner, F.; Stuefert, S.; Scherer, M.

    1991-01-01

    The use of high-resolution US equipments in the examination of the newborn hip allowed the evaluation of a thin echogenic stripe (the internal capsule stripe), which defines laterally the acetabular hyaline cartilage. By means of an anatomo-histological preparation the echogenic stripe can be related to either the capsular circular fibres or the interface between the latter and the hyaline cartilage. The internal capsular stripe, together with the echogenic synovial stripe, precisely delimit the whole acetabular hyaline cartilage. Further-more, in many babies high-resolution US sometimes fails to demonstrate Graft's 'perichondral gap', so that an accurate anatomic knowledge of the hip becomes necessary in the evaluation of acetabular labrum

  2. Combined sodium ion sensitivity in agonist binding and internalization of vasopressin V1b receptors.

    Science.gov (United States)

    Koshimizu, Taka-Aki; Kashiwazaki, Aki; Taniguchi, Junichi

    2016-05-03

    Reducing Na(+) in the extracellular environment may lead to two beneficial effects for increasing agonist binding to cell surface G-protein coupled receptors (GPCRs): reduction of Na(+)-mediated binding block and reduce of receptor internalization. However, such combined effects have not been explored. We used Chinese Hamster Ovary cells expressing vasopressin V1b receptors as a model to explore Na(+) sensitivity in agonist binding and receptor internalization. Under basal conditions, a large fraction of V1b receptors is located intracellularly, and a small fraction is in the plasma membrane. Decreases in external Na(+) increased cell surface [(3)H]AVP binding and decreased receptor internalization. Substitution of Na(+) by Cs(+) or NH4(+) inhibited agonist binding. To suppress receptor internalization, the concentration of NaCl, but not of CsCl, had to be less than 50 mM, due to the high sensitivity of the internalization machinery to Na(+) over Cs(+). Iso-osmotic supplementation of glucose or NH4Cl maintained internalization of the V1b receptor, even in a low-NaCl environment. Moreover, iodide ions, which acted as a counter anion, inhibited V1b agonist binding. In summary, we found external ionic conditions that could increase the presence of high-affinity state receptors at the cell surface with minimum internalization during agonist stimulations.

  3. Visual recognition memory, manifest as long-term habituation, requires synaptic plasticity in V1

    Science.gov (United States)

    Cooke, Sam F.; Komorowski, Robert W.; Kaplan, Eitan S.; Gavornik, Jeffrey P.; Bear, Mark F.

    2015-01-01

    Familiarity with stimuli that bring neither reward nor punishment, manifested through behavioural habituation, enables organisms to detect novelty and devote cognition to important elements of the environment. Here we describe in mice a form of long-term behavioural habituation to visual grating stimuli that is selective for stimulus orientation. Orientation-selective habituation (OSH) can be observed both in exploratory behaviour in an open arena, and in a stereotyped motor response to visual stimuli in head-restrained mice. We show that the latter behavioural response, termed a vidget, requires V1. Parallel electrophysiological recordings in V1 reveal that plasticity, in the form of stimulus-selective response potentiation (SRP), occurs in layer 4 of V1 as OSH develops. Local manipulations of V1 that prevent and reverse electrophysiological modifications likewise prevent and reverse memory demonstrated behaviourally. These findings suggest that a form of long-term visual recognition memory is stored via synaptic plasticity in primary sensory cortex. PMID:25599221

  4. Developing iCare v.1.0: an academic electronic health record.

    Science.gov (United States)

    Wyatt, Tami H; Li, Xueping; Indranoi, Chayawat; Bell, Matthew

    2012-06-01

    An electronic health record application, iCare v.1.0, was developed and tested that allows data input and retrieval while tracking student performance over time. The development and usability testing of iCare v.1.0 followed a rapid prototyping software development and testing model. Once the functionality was tested by engineers, the usability and feasibility testing began with a convenience sample of focus group members including undergraduate and graduate students and faculty. Three focus groups were created, and four subjects participated in each focus group (n = 12). Nielsen's usability heuristics and methods of evaluation were used to evaluate data captured from each focus group. Overall, users wanted a full-featured electronic health record with features that coached or guided users. The earliest versions of iCare v.1.0 did not provide help features and prompts to guide students but were later added. Future versions will incorporate a full-featured help section. The interface and design of iCare v.1.0 are similar to professional electronic health record applications. As a result of this usability study, future versions of iCare will include more robust help features along with advanced reporting and elements specific to specialty populations such as pediatrics and mental health services.

  5. A new allergen from ragweed (Ambrosia artemisiifolia) with homology to art v 1 from mugwort.

    Science.gov (United States)

    Léonard, Renaud; Wopfner, Nicole; Pabst, Martin; Stadlmann, Johannes; Petersen, Bent O; Duus, Jens Ø; Himly, Martin; Radauer, Christian; Gadermaier, Gabriele; Razzazi-Fazeli, Ebrahim; Ferreira, Fatima; Altmann, Friedrich

    2010-08-27

    Art v 1, the major pollen allergen of the composite plant mugwort (Artemisia vulgaris) has been identified recently as a thionin-like protein with a bulky arabinogalactan-protein moiety. A close relative of mugwort, ragweed (Ambrosia artemisiifolia) is an important allergen source in North America, and, since 1990, ragweed has become a growing health concern in Europe as well. Weed pollen-sensitized patients demonstrated IgE reactivity to a ragweed pollen protein of apparently 29-31 kDa. This reaction could be inhibited by the mugwort allergen Art v 1. The purified ragweed pollen protein consisted of a 57-amino acid-long defensin-like domain with high homology to Art v 1 and a C-terminal proline-rich domain. This part contained hydroxyproline-linked arabinogalactan chains with one galactose and 5 to 20 and more alpha-arabinofuranosyl residues with some beta-arabinoses in terminal positions as revealed by high field NMR. The ragweed protein contained only small amounts of the single hydroxyproline-linked beta-arabinosyl residues, which form an important IgE binding determinant in Art v 1. cDNA clones for this protein were obtained from ragweed flowers. Immunological characterization revealed that the recombinant ragweed protein reacted with >30% of the weed pollen allergic patients. Therefore, this protein from ragweed pollen constitutes a novel important ragweed allergen and has been designated Amb a 4.

  6. Optical, mechanical and TEM assessment of titania-doped Bi2V1 ...

    Indian Academy of Sciences (India)

    2016-08-26

    Aug 26, 2016 ... Home; Journals; Bulletin of Materials Science; Volume 37; Issue 7. Optical, mechanical and TEM assessment of titania-doped Bi2V1−TiO5.5−δ bismuth vanadate oxides. Gurbinder Kaur Gary Pickrell Vishal Kumar Om Prakash Pandey Kulvir Singh Daniel Homa. Volume 37 Issue 7 December 2014 pp ...

  7. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

    NARCIS (Netherlands)

    Doria-Rose, Nicole A.; Schramm, Chaim A.; Gorman, Jason; Moore, Penny L.; Bhiman, Jinal N.; Dekosky, Brandon J.; Ernandes, Michael J.; Georgiev, Ivelin S.; Kim, Helen J.; Pancera, Marie; Staupe, Ryan P.; Altae-Tran, Han R.; Bailer, Robert T.; Crooks, Ema T.; Cupo, Albert; Druz, Aliaksandr; Garrett, Nigel J.; Hoi, Kam H.; Kong, Rui; Louder, Mark K.; Longo, Nancy S.; McKee, Krisha; Nonyane, Molati; O'Dell, Sijy; Roark, Ryan S.; Rudicell, Rebecca S.; Schmidt, Stephen D.; Sheward, Daniel J.; Soto, Cinque; Wibmer, Constantinos Kurt; Yang, Yongping; Zhang, Zhenhai; Mullikin, James C.; Binley, James M.; Sanders, Rogier W.; Wilson, Ian A.; Moore, John P.; Ward, Andrew B.; Georgiou, George; Williamson, Carolyn; Abdool Karim, Salim S.; Morris, Lynn; Kwong, Peter D.; Shapiro, Lawrence; Mascola, John R.; Becker, Jesse; Benjamin, Betty; Blakesley, Robert; Bouffard, Gerry; Brooks, Shelise; Coleman, Holly; Dekhtyar, Mila; Gregory, Michael; Guan, Xiaobin; Gupta, Jyoti; Han, Joel; Hargrove, April; Ho, Shi-ling; Johnson, Taccara; Legaspi, Richelle; Lovett, Sean; Maduro, Quino; Masiello, Cathy; Maskeri, Baishali; McDowell, Jenny; Montemayor, Casandra; Mullikin, James; Park, Morgan; Riebow, Nancy; Schandler, Karen; Schmidt, Brian; Sison, Christina; Stantripop, Mal; Thomas, James; Thomas, Pam; Vemulapalli, Meg; Young, Alice

    2014-01-01

    Antibodies capable of neutralizing HIV-1 often target variable regions 1 and 2 (V1V2) of the HIV-1 envelope, but the mechanism of their elicitation has been unclear. Here we define the developmental pathway by which such antibodies are generated and acquire the requisite molecular characteristics

  8. GEOCLIM reloaded (v 1.0): a new coupled earth system model for past climate change

    NARCIS (Netherlands)

    Arndt, S.; Regnier, P.; Goddéris, Y.; Donnadieu, Y.

    2011-01-01

    We present a new version of the coupled Earth system model GEOCLIM. The new release, GEOCLIM reloaded (v 1.0), links the existing atmosphere and weathering modules to a novel, temporally and spatially resolved model of the global ocean circulation, which provides a physical framework for a

  9. Role of vasopressin V1a receptor in ∆9-tetrahydrocannabinol-induced cataleptic immobilization in mice.

    Science.gov (United States)

    Egashira, Nobuaki; Koushi, Emi; Myose, Takayuki; Tanoue, Akito; Mishima, Kenichi; Tsuchihashi, Ryota; Kinjo, Junei; Tanaka, Hiroyuki; Morimoto, Satoshi; Iwasaki, Katsunori

    2017-12-01

    Cannabis is a widely used illicit substance. ∆ 9 -tetrahydrocannabinol (THC), the major psychoactive component of cannabis, is known to cause catalepsy in rodents. Recent studies have shown that vasopressin V1a and V1b receptors are widely distributed in the central nervous system and are capable of influencing a wide variety of brain functions such as social behavior, emotionality, and learning and memory. The present study was designed to examine the possible involvement of V1a and V1b receptors in THC-induced catalepsy-like immobilization. The induction of catalepsy following treatment with THC (10 mg/kg, i.p.) or haloperidol (1 mg/kg, i.p.) was evaluated in wild-type (WT), V1a receptor knockout (V1aRKO), and V1b receptor knockout (V1bRKO) mice. The effect of treatment with the selective 5-hydroxytryptamine 1A receptor antagonist WAY100635 (0.1 mg/kg, i.p.) on THC-induced catalepsy was also evaluated in V1aRKO mice. Moreover, the effects of the V1a receptor antagonist VMAX-357 and the V1b receptor antagonist ORG-52186 on THC-induced catalepsy were evaluated in ddY mice. THC and haloperidol markedly caused catalepsy in V1bRKO mice as well as in WT mice. However, V1aRKO mice exhibited a reduction in catalepsy induced by THC but not by haloperidol. WAY100635 dramatically enhanced THC-induced catalepsy in V1aRKO mice. Although VMAX-357 (10 mg/kg, p.o.) but not ORG-52186 significantly attenuated THC-induced catalepsy, it had no significant effect on the enhancement of THC-induced catalepsy by WAY100635 in ddY mice. These findings suggest that V1a receptor regulates THC-induced catalepsy-like immobilization.

  10. Fine Mapping of Virescent Leaf Gene v-1 in Cucumber (Cucumis sativus L.

    Directory of Open Access Journals (Sweden)

    Han Miao

    2016-09-01

    Full Text Available Leaf color mutants are common in higher plants that can be used as markers in crop breeding or as an important tool in understanding regulatory mechanisms in chlorophyll biosynthesis and chloroplast development. In virescent leaf mutants, young leaves are yellow in color, which gradually return to normal green when the seedlings grow large. In the present study, we conducted phenotypic characterization and genetic mapping of the cucumber virescent leaf mutant 9110Gt conferred by the v-1 locus. Total chlorophyll and carotenoid content in 9110Gt was reduced by 44% and 21%, respectively, as compared with its wild type parental line 9110G. Electron microscopic investigation revealed fewer chloroplasts per cell and thylakoids per chloroplast in 9110Gt than in 9110G. Fine genetic mapping allowed for the assignment of the v-1 locus to a 50.4 kb genomic DNA region in chromosome 6 with two flanking markers that were 0.14 and 0.16 cM away from v-1, respectively. Multiple lines of evidence supported CsaCNGCs as the only candidate gene for the v-1 locus, which encoded a cyclic-nucleotide-gated ion channel protein. A single nucleotide change in the promoter region of v-1 seemed to be associated with the virescent color change in 9110Gt. Real-time PCR revealed significantly lower expression of CsaCNGCs in the true leaves of 9110Gt than in 9110G. This was the first report that connected the CsaCNGCs gene to virescent leaf color change, which provided a useful tool to establish linkages among virescent leaf color change, chloroplast development, chlorophyll biosynthesis, and the functions of the CsaCNGCs gene.

  11. Oral vaccination and protection of striped skunks (Mephitis mephitis) against rabies using ONRAB®.

    Science.gov (United States)

    Brown, L J; Rosatte, R C; Fehlner-Gardiner, C; Ellison, J A; Jackson, F R; Bachmann, P; Taylor, J S; Franka, R; Donovan, D

    2014-06-17

    Skunks are one of the most important rabies vector species in North America due to their wide geographic distribution, high susceptibility to the rabies virus, and tendency to inhabit areas around human dwellings and domestic animals. Oral vaccination is a cost-effective, socially acceptable technique often used to control rabies in terrestrial wildlife; however, control of rabies in skunks has proven especially challenging due to the lack of a vaccine effective by the oral route in this species. In this study, we examined the antibody response of captive striped skunks (Mephitis mephitis) to ONRAB(®) and tested the protection afforded by the vaccine against rabies virus. Thirty-one skunks were each offered one ONRAB(®) vaccine bait, 25 skunks were administered ONRAB(®) via direct instillation into the oral cavity (DIOC) and ten controls received no vaccine. A blood sample was collected from controls and vaccinates 6 weeks prior to treatment, and then 5 and 7 weeks post-vaccination (PV). A competitive ELISA was used to detect rabies antibody (RAb). Pre-vaccination sera for all skunks, and sera for all controls throughout the serology study, were negative for RAb. Fifty-eight percent (18/31) of skunks in the bait group and 100% (25/25) of skunks that received ONRAB(®) DIOC had detectable RAb by 7 week PV. All 10 controls succumbed to experimental rabies infection. In the group of skunks administered ONRAB(®) DIOC, 100% (23/23) survived challenge 247 days PV. Survival of skunks presented ONRAB(®) baits was 81% (25/31). In the bait group, all 18 skunks that had detectable RAb by 7 week PV survived challenge. Seven additional skunks without detectable RAb prior to week 7 PV also survived. Lack of any remarkable pathology in study animals, together with positive serology and challenge results, supports that ONRAB(®) is a safe and effective oral rabies vaccine for use in skunks. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Evaluation of Immune-Related Response Criteria and RECIST v1.1 in Patients With Advanced Melanoma Treated With Pembrolizumab.

    Science.gov (United States)

    Hodi, F Stephen; Hwu, Wen-Jen; Kefford, Richard; Weber, Jeffrey S; Daud, Adil; Hamid, Omid; Patnaik, Amita; Ribas, Antoni; Robert, Caroline; Gangadhar, Tara C; Joshua, Anthony M; Hersey, Peter; Dronca, Roxana; Joseph, Richard; Hille, Darcy; Xue, Dahai; Li, Xiaoyun Nicole; Kang, S Peter; Ebbinghaus, Scot; Perrone, Andrea; Wolchok, Jedd D

    2016-05-01

    We evaluated atypical response patterns and the relationship between overall survival and best overall response measured per immune-related response criteria (irRC) and Response Evaluation Criteria in Solid Tumors, version 1.1 (RECIST v1.1) in patients with advanced melanoma treated with pembrolizumab in the phase Ib KEYNOTE-001 study (clinical trial information: NCT01295827). Patients received pembrolizumab 2 or 10 mg/kg every 2 weeks or every 3 weeks. Atypical responses were identified by using centrally assessed irRC data in patients with ≥ 28 weeks of imaging. Pseudoprogression was defined as ≥ 25% increase in tumor burden at week 12 (early) or any assessment after week 12 (delayed) that was not confirmed as progressive disease at next assessment. Response was assessed centrally per irRC and RECIST v1.1. Of the 655 patients with melanoma enrolled, 327 had ≥ 28 weeks of imaging follow-up. Twenty-four (7%) of these 327 patients had atypical responses (15 [5%] with early pseudoprogression and nine [3%] with delayed pseudoprogression). Of the 592 patients who survived ≥ 12 weeks, 84 (14%) experienced progressive disease per RECIST v1.1 but nonprogressive disease per irRC. Two-year overall survival rates were 77.6% in patients with nonprogressive disease per both criteria (n = 331), 37.5% in patients with progressive disease per RECIST v1.1 but nonprogressive disease per irRC (n = 84), and 17.3% in patients with progressive disease per both criteria (n = 177). Atypical responses were observed in patients with melanoma treated with pembrolizumab. Based on survival analysis, conventional RECIST might underestimate the benefit of pembrolizumab in approximately 15% of patients; modified criteria that permit treatment beyond initial progression per RECIST v1.1 might prevent premature cessation of treatment. © 2016 by American Society of Clinical Oncology.

  13. Histological features of layers and sublayers in cortical visual areas V1 and V2 of chimpanzees, macaque monkeys, and humans

    Directory of Open Access Journals (Sweden)

    Balaram P

    2014-09-01

    Full Text Available Pooja Balaram, Nicole A Young, Jon H Kaas Department of Psychology, Vanderbilt University, Nashville, TN, USA Abstract: The layers and sublayers of primary visual cortex, or V1, in primates are easily distinguishable compared to those in other cortical areas, and are especially distinct in anthropoid primates – monkeys, apes, and humans – where they also vary in histological appearance. This variation in primate-specific specialization has led to a longstanding confusion over the identity of layer 4 and its proposed sublayers in V1. As the application of different histological markers relate to the issue of defining and identifying layers and sublayers, we applied four traditional and four more recent histological markers to brain sections of V1 and adjoining secondary visual cortex (V2 in macaque monkeys, chimpanzees, and humans in order to compare identifiable layers and sublayers in both cortical areas across these species. The use of Nissl, neuronal nuclear antigen (NeuN, Gallyas myelin, cytochrome oxidase (CO, acetylcholinesterase (AChE, nonphosphorylated neurofilament H (SMI-32, parvalbumin (PV, and vesicular glutamate transporter 2 (VGLUT2 preparations support the conclusion that the most popular scheme of V1 lamination, that of Brodmann, misidentifies sublayers of layer 3 (3Bβ and 3C as sublayers of layer 4 (4A and 4B, and that the specialized sublayer of layer 3 in monkeys, 3Bβ, is not present in humans. These differences in interpretation are important as they relate to the proposed functions of layer 4 in primate species, where layer 4 of V1 is a layer that receives and processes information from the visual thalamus, and layer 3 is a layer that transforms and distributes information to other cortical areas. Keywords: area 17, area 18, cortical layers, histology, immunohistochemistry

  14. Histological features of layers and sublayers in cortical visual areas V1 and V2 of chimpanzees, macaque monkeys, and humans.

    Science.gov (United States)

    Balaram, Pooja; Young, Nicole A; Kaas, Jon H

    2014-09-01

    The layers and sublayers of primary visual cortex, or V1, in primates are easily distinguishable compared to those in other cortical areas, and are especially distinct in anthropoid primates - monkeys, apes, and humans - where they also vary in histological appearance. This variation in primate-specific specialization has led to a longstanding confusion over the identity of layer 4 and its proposed sublayers in V1. As the application of different histological markers relate to the issue of defining and identifying layers and sublayers, we applied four traditional and four more recent histological markers to brain sections of V1 and adjoining secondary visual cortex (V2) in macaque monkeys, chimpanzees, and humans in order to compare identifiable layers and sublayers in both cortical areas across these species. The use of Nissl, neuronal nuclear antigen (NeuN), Gallyas myelin, cytochrome oxidase (CO), acetylcholinesterase (AChE), nonphosphorylated neurofilament H (SMI-32), parvalbumin (PV), and vesicular glutamate transporter 2 (VGLUT2) preparations support the conclusion that the most popular scheme of V1 lamination, that of Brodmann, misidentifies sublayers of layer 3 (3Bβ and 3C) as sublayers of layer 4 (4A and 4B), and that the specialized sublayer of layer 3 in monkeys, 3Bβ, is not present in humans. These differences in interpretation are important as they relate to the proposed functions of layer 4 in primate species, where layer 4 of V1 is a layer that receives and processes information from the visual thalamus, and layer 3 is a layer that transforms and distributes information to other cortical areas.

  15. Inheritance of trunk striping in the Sumatran tiger barb, Barbus tetrazona.

    Science.gov (United States)

    Frankel, J S

    1985-01-01

    The Sumatran tiger barb, Barbus tetrazona, exhibits three truck (pelvic) striping phenotypes: complete, incomplete, and half banded. Segregation patterns observed in the progeny from 12 different matings indicate that the inheritance of these phenotypes is controlled by two autosomal gene loci acting additively, with complete dominance at each locus.

  16. Helminths of sympatric striped, hog-nosed, and spotted skunks in west-central Texas.

    Science.gov (United States)

    Neiswenter, Sean A; Pence, Danny B; Dowler, Robert C

    2006-07-01

    Twenty-eight hog-nosed skunks (Conepatus leuconotus), 23 striped skunks (Mephitis mephitis), and nine spotted skunks (Spilogale gracilis) from an area of sympatry in west-central Texas were examined for helminth parasites. Shared helminth species among all three host species were one nematode (Physaloptera maxillaris), two acanthocephalans (Pachysentis canicola, Macracanthorhynchus ingens), and one cestode (Mathevotaenia mephitis). Two nematodes (Gongylonema sp. and Filaria taxidaea) occurred in both the striped and hog-nosed skunks. One nematode (Filaroides milksi) and one acanthocephalan (Oncicola canis) were collected only from C. leuconotus. The most common helminth infections for striped and hog-nosed skunks were P. maxillaris and P. canicola. Helminth species richness was highest in hog-nosed skunks, but striped skunks had the highest prevalences and intensities of all the common helminth species. The helminth fauna of spotted skunks was markedly depauperate in terms of species richness and helminth abundance compared to the other two host species. Differences in helminth communities across these three sympatric skunks may be related to differences in their relative abundance, behavior, food habits, and geographic range.

  17. Improving sustainability of striped catfish (Pangasianodon hypophthalmus) farming in the Mekong Delta, Vietnam through recirculation technology

    NARCIS (Netherlands)

    Nguyen, Nhut

    2016-01-01

    The aim of this thesis was to document improvements in sustainability indicators of striped catfish (Pangasianodon hypophthalmus, Sauvage, 1878) production through the application of recirculation and waste treatment techniques. To be able to document improvements in sustainability, in each

  18. 3D Measurement Technology by Structured Light Using Stripe-Edge-Based Gray Code

    International Nuclear Information System (INIS)

    Wu, H B; Chen, Y; Wu, M Y; Guan, C R; Yu, X Y

    2006-01-01

    The key problem of 3D vision measurement using triangle method based on structured light is to acquiring projecting angle of projecting light accurately. In order to acquire projecting angle thereby determine the corresponding relationship between sampling point and image point, method for encoding and decoding structured light based on stripe edge of Gray code is presented. The method encoded with Gray code stripe and decoded with stripe edge acquired by sub-pixel technology instead of pixel centre, so latter one-bit decoding error was removed. Accuracy of image sampling point location and correspondence between image sampling point and object sampling point achieved sub-pixel degree. In addition, measurement error caused by dividing projecting angle irregularly by even-width encoding stripe was analysed and corrected. Encoding and decoding principle and decoding equations were described. Finally, 3dsmax and Matlab software were used to simulate measurement system and reconstruct measured surface. Indicated by experimental results, measurement error is about 0.05%

  19. Hypoxia tolerance and partitioning of bimodal respiration in the striped catfish (Pangasianodon hypophthalmus)

    DEFF Research Database (Denmark)

    Lefevre, Sjannie; Huong, Do Thi Thanh; Wang, Tobias

    2011-01-01

    Air-breathing fish are common in the tropics, and their importance in Asian aquaculture is increasing, but the respiratory physiology of some of the key species such as the striped catfish, Pangasianodon hypophthalmus Sauvage 1878 is unstudied. P. hypophthalmus is an interesting species as it app...

  20. The effect of freezing rate on the quality of Striped Bass Spermatozoa

    Science.gov (United States)

    Several studies have been conducted in an attempt to determine the optimal freezing rate for the cryopreservation of striped bass (Morone saxatilis) spermatozoa. In this study, the effects of freezing rate (-10, -15, -20 and -40oC/minute) on gamete quality including, viability, motion characteristi...

  1. Variation in the timing of reproduction of the four-striped field mouse ...

    African Journals Online (AJOL)

    We used the four-striped field mouse, Rhabdomys pumilio (Sparrmann, 1784), to test the hypothesis that reproduction in a small, short-lived mammal will be opportunistic, characterized by temporal and spatial variation in the timing of events, and only be inhibited under harsh and predictable winter conditions. Field mice ...

  2. Genetic analysis and location of gene for resistance to stripe rust in ...

    Indian Academy of Sciences (India)

    2013-08-06

    Aug 6, 2013 ... to rust race CYR26. The gene YrSD in Strube Dickkopf resistant to stripe rust CYR26 using SSR method was located on chromosome 5B. There are four pairs (Wmc640,. Barc59, Wmc783 and Wms497) polymorphic SSR primers on chromosome 5B which produced polymorphic DNA bands between the ...

  3. Luminous Obscured AGN Unveiled in the Stripe 82 X-ray Survey

    Science.gov (United States)

    LaMassa, Stephanie; Glikman, Eilat; Brusa, Marcella; Rigby, Jane; Tasnim Ananna, Tonima; Stern, Daniel; Lira, Paulina; Urry, Meg; Salvato, Mara; Alexandroff, Rachael; Allevato, Viola; Cardamone, Carolin; Civano, Francesca Maria; Coppi, Paolo; Farrah, Duncan; Komossa, S.; Lanzuisi, Giorgio; Marchesi, Stefano; Richards, Gordon; Trakhtenbrot, Benny; Treister, Ezequiel

    2018-01-01

    Stripe 82X is a wide-area (30 deg2) X-ray survey overlapping the legacy Sloan Digital Sky Survey (SDSS) Stripe 82 field, designed to uncover rare, high luminosity active galactic nuclei (AGN). We report on the results of an on-going near-infrared (NIR) spectroscopic campaign to follow-up reddened AGN candidates with Palomar TripleSpec, Keck NIRSPEC, and Gemini GNIRS. We identified 8 AGN in our bright NIR sample (K colors (> 4, Vega); four of these sources had existing optical spectra in SDSS. We targeted four out of 34 obscured AGN candidates in our faint NIR sample (K > 17, Vega), all of which are undetected in the single-epoch SDSS imaging, making them the best candidates for the most obscured and/or the most distant reddend AGN in Stripe 82X. All twelve sources are Type 1 AGN, with the FWHM of at least one permitted emission line exceeding 1300 km/s. We find that our nearly complete bright NIR sample (12/13 obscured AGN candidates have spectroscopic redshifts) is more distant (z > 0.5) than a matched sample of blue Type 1 AGN from Stripe 82X; these AGN tend to be more luminous than their blue, unobscured counterparts. Results from our pilot program of faint NIR-selected obscured AGN candidates demonstrate that our selection recovers reddened quasars missed by SDSS.

  4. Quantifying sustainability indicators in striped catfish Pangasianodon hypophthalmus downstream and upstream ponds

    NARCIS (Netherlands)

    Nhut, N.; Hao, N.V.; Bosma, R.H.; Verreth, J.A.V.; Verdegem, M.C.J.; Eding, E.H.

    2017-01-01

    To assess the potential for improving sustainability and efficiency in an important Vietnamese finfish culture, we quantified sustainability indicators for 2 downstream and 2 upstream 3 to 4 m deep ponds for striped catfish Pangasianodon hypophthalmus (Sauvage, 1878) production along the Mekong

  5. Parallel carbon nanotube stripes in polymer thin film with remarkable conductive anisotropy.

    Science.gov (United States)

    Huang, Jinrui; Zhu, Yutian; Jiang, Wei; Yin, Jinghua; Tang, Qingxin; Yang, Xiaodong

    2014-02-12

    In our previous study ( Mao et al. J. Phys. Chem. Lett. 2013 , 4 , 43 - 47 ), we proposed a novel method, that is, the shear-flow-induced hierarchical self-assembly of two-dimensional fillers (octadecylamine-functionalized graphene) into the well-ordered parallel stripes in a polymer matrix, to fabricate the anisotropic conductive materials. In this study, we extend this method to one-dimensional multiwalled carbon nanotubes (MWCNTs). Under the induction of shear flow, the dispersed poly(styrene ethylene/butadiene-styrene) (SEBS) phase and MWCNTs can spontaneously assemble into well-ordered parallel stripes in the polypropylene (PP) thin film. The electrical measurements indicate that the electrical resistivity in the direction parallel to the stripes is almost 6 orders of magnitude lower than that in the perpendicular direction, which is by far the most striking conductive anisotropy for the plastic anisotropic conductive materials. In addition, it is found that the size of the MWCNT stripe as well as the electrical property of the resulting anisotropic conductive thin film can be well-controlled by the gap of the shear cell.

  6. Post-epizootic chronic dolphin morbillivirus infection in Mediterranean striped dolphins Stenella coeruleoalba.

    Science.gov (United States)

    Soto, Sara; Alba, Ana; Ganges, Llilianne; Vidal, Enric; Raga, Juan Antonio; Alegre, Ferrán; González, Beatriz; Medina, Pascual; Zorrilla, Irene; Martínez, Jorge; Marco, Alberto; Pérez, Mónica; Pérez, Blanca; Pérez de Vargas Mesas, Ana; Martínez Valverde, Rosa; Domingo, Mariano

    2011-10-06

    Dolphin morbillivirus (DMV) has caused 2 epizootics with high mortality rates on the Spanish Mediterranean coast, in 1990 and 2006-07, mainly affecting striped dolphins Stenella coeruleoalba. Following the first epizootic unusual DMV infections affecting only the central nervous system of striped dolphins were found, with histological features similar to subacute sclerosing panencephalitis and old dog encephalitis, the chronic latent localised infections caused by defective forms of measles virus and canine distemper virus, respectively. Between 2008 and 2010, monitoring by microscopic and immunohistochemical (IHC) studies of 118 striped dolphins stranded along Catalonia, the Valencia Region and Andalusia showed similar localised DMV nervous system infections in 25.0, 28.6 and 27.4% of cases, respectively, with no significant differences among regions or sex. The body length of DMV-infected dolphins was statistically greater than that of non-infected dolphins (196.5 vs. 160.5 cm; p dolphins with positive IHC-DMV had positive PCR results. All 6 cases were positive with the 78 bp RT-PCR. These findings contraindicate the use of the 429 bp RT-PCR protocol based on the P gene to detect this specific form of DMV. DMV localised nervous infection constitutes the most relevant single cause of stranding and death in Mediterranean striped dolphins in the years following a DMV epizootic, and it might even overwhelm the effects of the epizootic itself, at least in 2007.

  7. Genetics of adult plant stripe rust resistance in CSP44, a selection ...

    Indian Academy of Sciences (India)

    Unknown

    areas of temperate zones (Johnson 1988). Yield losses can be considerable, ranging from about 40 per cent to com- plete destruction of the crop depending upon the growth stage at which the disease attacks. Using diverse genes for resistance against stripe rust disease is the most eco- nomical and environmentally safe ...

  8. Molecular mapping of a stripe rust resistance gene in wheat line C51

    Indian Academy of Sciences (India)

    Stripe rust, a major disease in areas where cool temperatures prevail, can strongly influence grain yield. To control this disease, breeders have incorporated seedling resistance genes from a variety of sources outside the primary wheat gene pool. The wheat line C51, introduced from the International Center for Agricultural ...

  9. Solar heat receiver

    Science.gov (United States)

    Hunt, Arlon J.; Hansen, Leif J.; Evans, David B.

    1985-01-01

    A receiver for converting solar energy to heat a gas to temperatures from 700.degree.-900.degree. C. The receiver is formed to minimize impingement of radiation on the walls and to provide maximum heating at and near the entry of the gas exit. Also, the receiver is formed to provide controlled movement of the gas to be heated to minimize wall temperatures. The receiver is designed for use with gas containing fine heat absorbing particles, such as carbon particles.

  10. Molecular investigations of pathogenesis-related Bet v 1 homologues in Passiflora (Passifloraceae).

    Science.gov (United States)

    Finkler, Carla; Giacomet, Carolina; Muschner, Valéria C; Salzano, Francisco M; Freitas, Loreta B

    2005-07-01

    The major birch pollen allergen, Bet v 1, responsible for allergic reactions in many areas of the world, is homologous to a large number of pathogenesis-related proteins (PRs), identified as PR10. As part of a long-range investigation of these types of proteins and of evolution in Passiflora, DNA sequences from eight Bet v 1 homologue isoforms were obtained from five species of this genus in Brazil, and their sequences compared among themselves and with 30 others from 8 different species, classified in different taxonomic units. The objective was a first characterization of these PRs in wild passionflowers, and their use for evolutionary and applied investigations. High interspecific, but low intraspecific variability was observed, as expected from multigenic families subjected to concerted evolution. The relationships obtained both within Passiflora and between it and seven other genera probably best reflect functional similarities than evolutionary history.

  11. Hyperfine properties of La(V1-xFex)O3 compounds

    Science.gov (United States)

    Tupan, L. F. S.; Ivashita, F. F.; Barco, R.; Hallouche, B.; Paesano, A.

    2017-11-01

    LaV1-xFexO3 perovskites were synthesized in the vanadium-rich concentration range (i.e., x properties of the iron nuclear probe. The aim of this investigation was to better understand the physical transformations that take place in the undoped compound (LaVO3) at low temperatures. For that, X-ray diffraction analysis and, more extensively, 57Fe Mössbauer spectroscopy were applied. The results revealed that the LaV1-xFexO3 vanadium-rich perovskites are orthorhombic at RT, and their lattice parameters decrease with increasing vanadium concentration. Lowering the temperature, the system becomes magnetic, with the iron moment freezing progressively. The presence of two magnetic subspectral components obtained at the lowest measurement temperatures suggests that the vanadium-rich samples, including LaVO3, undergo a phase transition from an orthorhombic to a monoclinic structure at low temperatures.

  12. Electronic, optical, and thermoelectric properties of Fe2+xV1−xAl

    Directory of Open Access Journals (Sweden)

    D. P. Rai

    2017-04-01

    Full Text Available We report the electronic, optical, and thermoelectric properties of full-Heusler alloy Fe2VAl with Fe antisite doping (Fe2+xV1−xAl as obtained from the first-principles Tran-Blaha modified Becke-Johnson potential. The results are discussed in relation to the available experimental data and show good agreements for the band gap, magnetic moment, and optical spectra. Exploring our transport data for thermoelectric applicability suggest that Fe2+xV1−xAl is a good candidate with a high figure of merit (ZT 0.75(0.65 for x = 0.25(0.50 at room temperature.

  13. MREG V1.1 : a multi-scale image registration algorithm for SAR applications.

    Energy Technology Data Exchange (ETDEWEB)

    Eichel, Paul H.

    2013-08-01

    MREG V1.1 is the sixth generation SAR image registration algorithm developed by the Signal Processing&Technology Department for Synthetic Aperture Radar applications. Like its predecessor algorithm REGI, it employs a powerful iterative multi-scale paradigm to achieve the competing goals of sub-pixel registration accuracy and the ability to handle large initial offsets. Since it is not model based, it allows for high fidelity tracking of spatially varying terrain-induced misregistration. Since it does not rely on image domain phase, it is equally adept at coherent and noncoherent image registration. This document provides a brief history of the registration processors developed by Dept. 5962 leading up to MREG V1.1, a full description of the signal processing steps involved in the algorithm, and a user's manual with application specific recommendations for CCD, TwoColor MultiView, and SAR stereoscopy.

  14. VICS82: The VISTA–CFHT Stripe 82 Near-infrared Survey

    Science.gov (United States)

    Geach, J. E.; Lin, Y.-T.; Makler, M.; Kneib, J.-P.; Ross, N. P.; Wang, W.-H.; Hsieh, B.-C.; Leauthaud, A.; Bundy, K.; McCracken, H. J.; Comparat, J.; Caminha, G. B.; Hudelot, P.; Lin, L.; Van Waerbeke, L.; Pereira, M. E. S.; Mast, D.

    2017-07-01

    We present the VISTA–CFHT Stripe 82 (VICS82) survey: a near-infrared (J+Ks) survey covering 150 square degrees of the Sloan Digital Sky Survey (SDSS) equatorial Stripe 82 to an average depth of J = 21.9 AB mag and Ks = 21.4 AB mag (80% completeness limits; 5σ point-source depths are approximately 0.5 mag brighter). VICS82 contributes to the growing legacy of multiwavelength data in the Stripe 82 footprint. The addition of near-infrared photometry to the existing SDSS Stripe 82 coadd ugriz photometry reduces the scatter in stellar mass estimates to δ {log}({M}\\star )≈ 0.3 dex for galaxies with {M}\\star > {10}9 {M}ȯ at z≈ 0.5, and offers improvement compared to optical-only estimates out to z≈ 1, with stellar masses constrained within a factor of approximately 2.5. When combined with other multiwavelength imaging of the Stripe, including moderate-to-deep ultraviolet (GALEX), optical and mid-infrared (Spitzer-IRAC) coverage, as well as tens of thousands of spectroscopic redshifts, VICS82 gives access to approximately 0.5 Gpc3 of comoving volume. Some of the main science drivers of VICS82 include (a) measuring the stellar mass function of {L}\\star galaxies out to z∼ 1; (b) detecting intermediate-redshift quasars at 2≲ z≲ 3.5; (c) measuring the stellar mass function and baryon census of clusters of galaxies, and (d) performing cross-correlation experiments of cosmic microwave background lensing in the optical/near-infrared that link stellar mass to large-scale dark matter structure. Here we define and describe the survey, highlight some early science results, and present the first public data release, which includes an SDSS-matched catalog as well as the calibrated pixel data themselves.

  15. Measurement Error Affects Risk Estimates for Recruitment to the Hudson River Stock of Striped Bass

    Directory of Open Access Journals (Sweden)

    Dennis J. Dunning

    2002-01-01

    Full Text Available We examined the consequences of ignoring the distinction between measurement error and natural variability in an assessment of risk to the Hudson River stock of striped bass posed by entrainment at the Bowline Point, Indian Point, and Roseton power plants. Risk was defined as the probability that recruitment of age-1+ striped bass would decline by 80% or more, relative to the equilibrium value, at least once during the time periods examined (1, 5, 10, and 15 years. Measurement error, estimated using two abundance indices from independent beach seine surveys conducted on the Hudson River, accounted for 50% of the variability in one index and 56% of the variability in the other. If a measurement error of 50% was ignored and all of the variability in abundance was attributed to natural causes, the risk that recruitment of age-1+ striped bass would decline by 80% or more after 15 years was 0.308 at the current level of entrainment mortality (11%. However, the risk decreased almost tenfold (0.032 if a measurement error of 50% was considered. The change in risk attributable to decreasing the entrainment mortality rate from 11 to 0% was very small (0.009 and similar in magnitude to the change in risk associated with an action proposed in Amendment #5 to the Interstate Fishery Management Plan for Atlantic striped bass (0.006— an increase in the instantaneous fishing mortality rate from 0.33 to 0.4. The proposed increase in fishing mortality was not considered an adverse environmental impact, which suggests that potentially costly efforts to reduce entrainment mortality on the Hudson River stock of striped bass are not warranted.

  16. Estimating abundance of adult striped bass in reservoirs using mobile hydroacoustics

    Science.gov (United States)

    Hightower, Joseph E.; Taylor, J. Christopher; Degan, Donald J.

    2013-01-01

    Hydroacoustic surveys have proven valuable for estimating reservoir forage fish abundance but are more challenging for adult predators such as striped bass Morone saxatilis. Difficulties in assessing striped bass in reservoirs include their low density and the inability to distinguish species with hydroacoustic data alone. Despite these difficulties, mobile hydroacoustic surveys have potential to provide useful data for management because of the large sample volume compared to traditional methods such as gill netting and the ability to target specific areas where striped bass are aggregated. Hydroacoustic estimates of reservoir striped bass have been made using mobile surveys, with data analysis using a threshold for target strength in order to focus on striped bass-sized targets, and auxiliary sampling with nets to obtain species composition. We provide recommendations regarding survey design, based in part on simulations that provide insight on the level of effort that would be required to achieve reasonable estimates of abundance. Future surveys may be able to incorporate telemetry or other sonar techniques such as side-scan or multibeam in order to focus survey efforts on productive habitats (within lake and vertically). However, species apportionment will likely remain the main source of error, and we see no hydroacoustic system on the horizon that will identify fish by species at the spatial and temporal scale required for most reservoir surveys. In situations where species composition can be reliably assessed using traditional gears, abundance estimates from hydroacoustic methods should be useful to fishery managers interested in developing harvest regulations, assessing survival of stocked juveniles, identifying seasonal aggregations, and examining predator–prey balance.

  17. Remapping of the stripe rust resistance gene Yr10 in common wheat.

    Science.gov (United States)

    Yuan, Cuiling; Wu, Jingzheng; Yan, Baiqiang; Hao, Qunqun; Zhang, Chaozhong; Lyu, Bo; Ni, Fei; Caplan, Allan; Wu, Jiajie; Fu, Daolin

    2018-02-23

    Yr10 is an important gene to control wheat stripe rust, and the search for Yr10 needs to be continued. Wheat stripe rust or yellow rust is a devastating fungal disease caused by Puccinia striiformis f. sp. tritici (Pst). Host disease resistance offers a primary source for controlling wheat stripe rust. The stripe rust resistance gene Yr10 confers the race-specific resistance to most tested Pst races in China including CYR29. Early studies proposed that Yr10 was a nucleotide-binding site, leucine-rich repeat gene archived as GenBank accession AF149112 (hereafter designated the Yr10 candidate gene or Yr10 CG ). In this study, we revealed that 15 Chinese wheat cultivars positive for Yr10 CG are susceptible to CYR29. We then expressed the Yr10 CG cDNA in the common wheat 'Bobwhite'. The Yr10 CG -cDNA positive transgenic plants were also susceptible to CYR29. Thus, it is highly unlikely that Yr10 CG corresponds to the Yr10 resistance gene. Using the Yr10 donor 'Moro' and the Pst-susceptible wheat 'Huixianhong', we generated two F 3 populations that displayed a single Mendelian segregation on the Yr10 gene, and used them to remap the Yr10 gene. Six markers were placed in the Yr10 region, with the Yr10 CG gene now mapping about 1.2-cM proximal to the Yr10 locus and the Xsdauw79 marker is completely linked to the Yr10 locus. Apparently, the Yr10 gene has not yet been identified. Fine mapping and positional cloning of Yr10 is important for gene pyramiding for stripe rust resistance in wheat.

  18. Differences in V1 and V2 ski skating techniques described by accelerometers.

    Science.gov (United States)

    Myklebust, H; Losnegard, T; Hallén, J

    2014-12-01

    The aims of the study were to describe the differences between the ski skating techniques V1 and V2 and evaluate reproducibility in complex cyclic hip movements measured by accelerometers. Fourteen elite senior male cross-country skiers rollerskied twice for 1 min (V1 and V2) at 4° inclination and 3 m/s. Tests were repeated after 20 min and again 4 months later. Five triaxial accelerometers were attached to the subject's hip (os sacrum), poles, and ski boots. Post-processing included transforming to an approximately global coordinate system, normalization for cycle time, double integration for displacement, and revealing temporal patterns. Different acceleration patterns between techniques and large correlation coefficients (Pearson's r = 0.6-0.9) between repeated trials were seen for most parameters. In V2, the hip was lowered [-10.9 (1.2) cm], whereas in V1, the hip was elevated [4.8 (1.5) cm] during the pole thrust. In conclusion, V2 but not V1 showed similarities to double poling in the way that potential energy is gained between poling strokes and transferred to propulsion during the poling action. Elite skiers reproduce their own individual patterns. One triaxial accelerometer on the lower back can distinguish techniques and might be useful in field research as well as in providing individual feedback on daily technique training. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Context matters: the illusive simplicity of macaque V1 receptive fields.

    Directory of Open Access Journals (Sweden)

    Robert Haslinger

    Full Text Available Even in V1, where neurons have well characterized classical receptive fields (CRFs, it has been difficult to deduce which features of natural scenes stimuli they actually respond to. Forward models based upon CRF stimuli have had limited success in predicting the response of V1 neurons to natural scenes. As natural scenes exhibit complex spatial and temporal correlations, this could be due to surround effects that modulate the sensitivity of the CRF. Here, instead of attempting a forward model, we quantify the importance of the natural scenes surround for awake macaque monkeys by modeling it non-parametrically. We also quantify the influence of two forms of trial to trial variability. The first is related to the neuron's own spike history. The second is related to ongoing mean field population activity reflected by the local field potential (LFP. We find that the surround produces strong temporal modulations in the firing rate that can be both suppressive and facilitative. Further, the LFP is found to induce a precise timing in spikes, which tend to be temporally localized on sharp LFP transients in the gamma frequency range. Using the pseudo R(2 as a measure of model fit, we find that during natural scene viewing the CRF dominates, accounting for 60% of the fit, but that taken collectively the surround, spike history and LFP are almost as important, accounting for 40%. However, overall only a small proportion of V1 spiking statistics could be explained (R(2∼5%, even when the full stimulus, spike history and LFP were taken into account. This suggests that under natural scene conditions, the dominant influence on V1 neurons is not the stimulus, nor the mean field dynamics of the LFP, but the complex, incoherent dynamics of the network in which neurons are embedded.

  20. Poblano v1.0 : a Matlab toolbox for gradient-based optimization.

    Energy Technology Data Exchange (ETDEWEB)

    Dunlavy, Daniel M.; Acar, Evrim (Sandia National Laboratories, Livermore, CA); Kolda, Tamara Gibson (Sandia National Laboratories, Livermore, CA)

    2010-03-01

    We present Poblano v1.0, a Matlab toolbox for solving gradient-based unconstrained optimization problems. Poblano implements three optimization methods (nonlinear conjugate gradients, limited-memory BFGS, and truncated Newton) that require only first order derivative information. In this paper, we describe the Poblano methods, provide numerous examples on how to use Poblano, and present results of Poblano used in solving problems from a standard test collection of unconstrained optimization problems.

  1. Monoclonal antibody-based ELISA to quantify the major allergen of Artemisia vulgaris pollen, Art v 1.

    Science.gov (United States)

    Jimeno, L; Duffort, O; Serrano, C; Barber, D; Polo, F

    2004-09-01

    Pollen of Artemisia vulgaris (mugwort) is a relevant cause of pollinosis in temperate and humid regions. Recently, the major allergen of this pollen, Art v 1, has been characterized. To develop a monoclonal antibody (mAb)-based enzyme-linked immunosorbent assay (ELISA) to quantify Art v 1, and to assess the correlation of Art v 1 content with the biological activity of mugwort pollen extracts. Art v 1-specific mAbs were obtained from a BALB/c mouse immunized with high-performance liquid chromatography (HPLC)-purified Art v 1. One of these antibodies (Av 3.7), which recognizes the N-terminal defensin-like domain of Art v 1, was used as the capture antibody in an ELISA method for allergen quantitation. An anti-A. vulgaris rabbit serum was used as the second antibody. Art v 1 was purified by immunoaffinity chromatography and used as the standard in the assay. The purity and identity of the affinity-purified Art v 1 was confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), mass spectrometry, amino acid composition, and N-terminal amino acid sequencing. The prevalence of specific IgE against Art v 1, determined by radioallergosorbent test (RAST) in a population of 44 mugwort-allergic patients, was 79%. The Art v 1-ELISA developed displays a detection limit of 0.1 ng/ml, and a practical working range of 0.2-10 ng/ml. The concentration of Art v 1 was measured in 10 A. vulgaris pollen extracts, and a good correlation was observed between the Art v 1 content and the allergenic activity of the extracts. The results prove the usefulness of the Art v 1-ELISA for the standardization of A. vulgaris pollen extracts intended for clinical use.

  2. Contribution of lateral interactions in V1 to organization of response properties.

    Science.gov (United States)

    Wright, J J; Alexander, D M; Bourke, P D

    2006-09-01

    We propose a model of self-organization of synaptic connections in V1, emphasizing lateral interactions. Subject to Hebbian learning with decay, evolution of synaptic strengths proceeds to a stable state in which all synapses are either saturated, or have minimum pre/post-synaptic coincidence. The most stable configuration gives rise to anatomically realistic "local maps", each of macro-columnar size, and each organized as Mobius projections of retinotopic space. A tiling of V1, constructed of approximately mirror-image reflections of each local map by its neighbors is formed, accounting for orientation-preference singularities, linear zones, and saddle points-with each map linked by connections between sites of common orientation preference. Ocular dominance columns are partly explained as a special case of the same process. The occurrence of direction preference fractures always in odd numbers around singularities is a specific feature explained by the Mobius configuration of the local map. Effects of stimulus velocity, orientation relative to direction of motion, and extension, upon orientation preference, which are not accounted for by spatial filtering, are explained by interactions between the classic receptive field and global V1.

  3. Revealing Detail along the Visual Hierarchy: Neural Clustering Preserves Acuity from V1 to V4.

    Science.gov (United States)

    Lu, Yiliang; Yin, Jiapeng; Chen, Zheyuan; Gong, Hongliang; Liu, Ye; Qian, Liling; Li, Xiaohong; Liu, Rui; Andolina, Ian Max; Wang, Wei

    2018-04-18

    How primates perceive objects along with their detailed features remains a mystery. This ability to make fine visual discriminations depends upon a high-acuity analysis of spatial frequency (SF) along the visual hierarchy from V1 to inferotemporal cortex. By studying the transformation of SF across macaque parafoveal V1, V2, and V4, we discovered SF-selective functional domains in V4 encoding higher SFs up to 12 cycles/°. These intermittent higher-SF-selective domains, surrounded by domains encoding lower SFs, violate the inverse relationship between SF preference and retinal eccentricity. The neural activities of higher- and lower-SF domains correspond to local and global features, respectively, of the same stimuli. Neural response latencies in high-SF domains are around 10 ms later than in low-SF domains, consistent with the coarse-to-fine nature of perception. Thus, our finding of preserved resolution from V1 into V4, separated both spatially and temporally, may serve as a connecting link for detailed object representation. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. A 'variable' stellar object in a variable blue nebula V-V 1-7

    International Nuclear Information System (INIS)

    Rao, N.K.; Gilra, D.P.

    1981-01-01

    V-V 1-7 is supposed to be one of the few planetary nebulae with Ao central stars and was included in the planetary-nebula catalogue as PK 235 + 1 0 1. The nebula was seen on the blue Palomar Observatory Sky Survey (POSS) print but not on the red print; as a result it was thought that it might be a reflection nebula. However, the symmetry of the nebula around the central star (HD 62001), and also the ultraviolet photometric variability of this central star led others to suggest that the nebula might be a nova shell. Subsequently it was found that the nebula V-V 1-7 has disappeared. It is not seen on any direct plate known to us except the POSS blue plate. In this paper the disappearance is reported (along with the nebula) of a stellar object, which appears within the 'nebular shell' of V-V 1-7 on the POSS blue plate, but not on the red plate. (author)

  5. Spatial Attention and Temporal Expectation Under Timed Uncertainty Predictably Modulate Neuronal Responses in Monkey V1

    Science.gov (United States)

    Sharma, Jitendra; Sugihara, Hiroki; Katz, Yarden; Schummers, James; Tenenbaum, Joshua; Sur, Mriganka

    2015-01-01

    The brain uses attention and expectation as flexible devices for optimizing behavioral responses associated with expected but unpredictably timed events. The neural bases of attention and expectation are thought to engage higher cognitive loci; however, their influence at the level of primary visual cortex (V1) remains unknown. Here, we asked whether single-neuron responses in monkey V1 were influenced by an attention task of unpredictable duration. Monkeys covertly attended to a spot that remained unchanged for a fixed period and then abruptly disappeared at variable times, prompting a lever release for reward. We show that monkeys responded progressively faster and performed better as the trial duration increased. Neural responses also followed monkey's task engagement—there was an early, but short duration, response facilitation, followed by a late but sustained increase during the time monkeys expected the attention spot to disappear. This late attentional modulation was significantly and negatively correlated with the reaction time and was well explained by a modified hazard function. Such bimodal, time-dependent changes were, however, absent in a task that did not require explicit attentional engagement. Thus, V1 neurons carry reliable signals of attention and temporal expectation that correlate with predictable influences on monkeys' behavioral responses. PMID:24836689

  6. Purification and characterization of the V1 vasopressin receptor from rat liver

    International Nuclear Information System (INIS)

    Fishman, J.B.; Dickey, B.F.; Attisano, C.; Fine, R.E.

    1987-01-01

    The rat liver V1 vasopressin receptor was purified approximately 21,000-fold from rat liver microsomes. The receptor was solubilized from membranes using the zwitterionic detergent CHAPS (3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate). Since the V1 receptor loses its ability to bind ligand when solubilized, the authors devised a liposome reconstitution system to assay vasopressin binding activity during purification. The purified receptor exhibits a K/sub d/ of 6 nm, when, prior to solubilization, the membranes were exposed to 1 μm vasopressin. This resulted in the association of a pertussis-toxin insensitive guanine-nucleotide binding protein with the receptor during most of the purification procedure. The authors are further characterizing the V1-associated G-proteins. In the absence of this association, the receptor has a K/sub d/ of 30 nM. Crosslinking of 125 I-vasopressin to a partially purified preparation of receptor demonstrated that the receptor had a molecular weight of approximately 68,000 under reducing conditions, and 58,000 under non-reducing conditions. The purification procedure may prove useful in purifying a number of small peptide hormone receptors (e.g., bradykinin, angiotensin II) and perhaps their associated G-proteins as well

  7. METEOR v1.0 - Design and structure of the software package

    International Nuclear Information System (INIS)

    Palomo, E.

    1994-01-01

    This script describes the structure and the separated modules of the software package METEOR for the statistical analysis of meteorological data series. It contains a systematic description of the subroutines of METEOR and, also, of the required shape for input and output files. The original version of METEOR have been developed by Ph.D. Elena Palomo, CIEMAT-IER, GIMASE. It is built by linking programs and routines written in FORTRAN 77 and it adds thc graphical capabilities of GNUPLOT. The shape of this toolbox was designed following the criteria of modularity, flexibility and agility criteria. All the input, output and analysis options are structured in three main menus: i) the first is aimed to evaluate the quality of the data set; ii) the second is aimed for pre-processing of the data; and iii) the third is aimed towards the statistical analyses and for creating the graphical outputs. Actually the information about METEOR is constituted by three documents written in spanish: 1) METEOR v1.0: User's guide; 2) METEOR v1.0: A usage example; 3) METEOR v 1.0: Design and structure of the software package. (Author)

  8. Development and Matching of Binocular Orientation Preference in Mouse V1

    Directory of Open Access Journals (Sweden)

    Basabi eBhaumik

    2014-07-01

    Full Text Available Eye-specific thalamic inputs converge in the primary visual cortex (V1 and form the basis of binocular vision. For normal binocular perceptions, such as depth and stereopsis, binocularly matched orientation preference between the two eyes is required. A critical period of binocular matching of orientation preference in mice during normal development is reported in literature. Using a reaction diffusion model we present the development of RF and orientation selectivity in mouse V1 and investigate the binocular orientation preference matching during the critical period. At the onset of the critical period the preferred orientations of the modeled cells are mostly mismatched in the two eyes and the mismatch decreases and reaches levels reported in juvenile mouse by the end of the critical period. At the end of critical period 39% of cells in binocular zone in our model cortex is orientation selective. In literature around 40% cortical cells are reported as orientation selective in mouse V1. The starting and the closing time for critical period determine the orientation preference alignment between the two eyes and orientation tuning in cortical cells. The absence of near neighbor interaction among cortical cells during the development of thalmo-cortical wiring causes a salt and pepper organization in the orientation preference map in mice. It also results in much lower % of orientation selective cells in mice as compared to ferrets and cats having organized orientation maps with pinwheels.

  9. Characterization and in vivo regulation of V1-type vasopressin receptors in the rat brain

    International Nuclear Information System (INIS)

    Shewey, L.M.

    1988-01-01

    Specific, high affinity binding sites for [ 3 H]-arginine 8 -vasopressin (AVP) have been characterized in Long-Evans rat septal membranes. Binding displacement studies with peptide analogs of AVP indicate that this binding site is similar to the V 1 (pressor)-type receptor for AVP. When added to rat brain septal slices that had been pre-labeled with [ 3 H]-myoinositol, AVP stimulated the accumulation of [ 3 H]-inositol-1-phosphate (IP 1 ) in the presence of lithium in a dose-dependent manner. This stimulation was completely inhibited by the specific V 1 antagonists, d(CH 2 ) 5 Tyr(Me)AVP, indicating that AVP stimulates hydrolysis of inositol phospholipids in rat brain septum through an interaction with V 1 -type AVP receptors. Binding studies of AVP receptors in the septum of heterozygous (HE) and homozygous, Brattleboro (BB) rats revealed an increased number of receptors with a lower affinity for AVP in the HO-BB rat when compared to the HE-BB rat. AVP-stimulated accumulation of [ 3 H]-IP 1 was significantly greater in the septum of the HO-BB rat than in the HE-BB rat. AVP receptor binding capacity correlated with release of [ 3 H]-IP 1 for all three groups studied

  10. The V1a and V1b, but not V2, vasopressin receptor genes are expressed in the supraoptic nucleus of the rat hypothalamus, and the transcripts are essentially colocalized in the vasopressinergic magnocellular neurons.

    Science.gov (United States)

    Hurbin, A; Boissin-Agasse, L; Orcel, H; Rabié, A; Joux, N; Desarménien, M G; Richard, P; Moos, F C

    1998-11-01

    We have identified and visualized the vasopressin (VP) receptors expressed by hypothalamic magnocellular neurons in supraoptic and paraventricular nuclei. To do this, we used RT-PCR on total RNA extracts from supraoptic nuclei or on single freshly dissociated supraoptic neurons, and in situ hybridization on frontal sections of hypothalamus of Wistar rats. The RT-PCR on supraoptic RNA extracts revealed that mainly V1a, but also V1b, subtypes of VP receptors are expressed from birth to adulthood. No V2 receptor messenger RNA (mRNA) was detected. Furthermore, the single-cell RT-nested PCR indicated that the V1a receptor mRNA is present in vasopressinergic magnocellular neurons. In light of these results, in situ hybridization was performed to visualize the V1a and V1b receptor mRNAs in supraoptic and paraventricular nuclei. Simultaneously, we coupled this approach to: 1) in situ hybridization detection of oxytocin or VP mRNAs; or 2) immunocytochemistry to detect the neuropeptides. This provided a way of identifying the neurons expressing perceptible amounts of V1a or V1b receptor mRNAs as vasopressinergic neurons. Here, we suggest that the autocontrol exerted specifically by VP on vasopressinergic neurons is mediated through, at least, V1a and V1b subtype receptors.

  11. Radiological characterisation of V1 NPP technological systems and buildings - Activation

    International Nuclear Information System (INIS)

    Kristofova, Kristina; Rapant, Tibor; Svitek, Jaroslav

    2012-01-01

    V1 NPP at Jaslovske Bohunice site has been finally shutdown after 28 years of successful operation in 2006 (Unit 1) and 2008 (Unit 2). At present, both units are finally shutdown and since July 2011 under decommissioning license. The preparation of V1 NPP decommissioning has been supported and partly financed by the Bohunice International Decommissioning Support Fund (BIDSF), under the administration of the European Bank for Reconstruction and Development. From 06/2008 to 12/2011 AMEC Nuclear Slovakia, together with partners STM Power and EWN GmbH, carried out BIDSF B6.4 project - Decommissioning database development (DDB). The main purpose of the B6.4 project was to develop a physical and radiological inventory database to support V1 NPP decommissioning process planning and performance. One of the specific deliverable tasks within the B6.4 project was deliverable D12 - Characterization of activated equipment and civil structures based on measurement, sampling and analyses performed on the samples. The scope of deliverable services within D12 task consisted of: 1. Categorization of activated components ; 2. Development of single working programs for their radiological monitoring and sampling ; 3. Preparation of sampling device and revision of all handling equipment; 4. Dose rate monitoring and sampling of: - Civil structures from reactors shaft on both units ; - Components placed in HLW storage, (so called 'Mogilnik') - connection rods, absorbers ; of control rod assemblies and neutron flux measurement channels ; - Reactor pressure vessel and shielding assemblies at both units of V1 NPP, reactor; internals from Unit 2 of V1 NPP; 5. Analysis of samples ; 6. Determination of radiological inventory ; 7. Import of radiological data for activated components into DDB. During sampling, mainly remotely controlled sampling device and radiation resistant camera with LED lightening for visual checking of all performed activities was used. In total, 125 samples have been taken

  12. Radiological characterisation on V1 NPP technological systems and buildings - Contamination

    International Nuclear Information System (INIS)

    Hanzel, Richard; Rapant, Tibor; Svitek, Jaroslav

    2012-01-01

    Since 2001, the preparation of V1 NPP practical decommissioning has been supported and partly financed by the Bohunice International Decommissioning Support Fund, under the administration of the European bank for Reconstruction and development. AMEC Nuclear Slovakia, together with partners STM Power and EWN GmbH, performed BIDSF B.4 project - Decommissioning database development. The main purpose of the B6.4 project was to develop a comprehensive physical and radiological inventory database to support RAW management development of the decommissioning studies and decommissioning project of Bohunice V1 NPP. AMEC Nuclear Slovakia was responsible mainly for DDB design, planning documents and physical and radiological characterization including sampling and analyses of the plant controlled area. The objective of V1 NPP radiological characterization was summarisation of sampling and analyses results, description of methodology used for radiological characterization and determination of the V1 NPP radiological inventory. Results of the characterization survey included the identification and distribution of contamination in buildings, structures, and other site facilities or other impacted media. The characterization survey clearly identified those portions of the site that have been affected by site activities and are contaminated. The survey also identified the portions of the site that have not been affected by these activities and can be marked as 'not impacted'. Radiological data have been presented also on the basis of index RAI level, where 5 radiological classes have been defined. On the basis of sampling and analyses results following radiological parameters have been assigned to all impacted components and civil structures included in DDB: dose rate in contact, dose rate in distance 1 m, external surface contamination, internal surface contamination and volume/mass contamination. Each room in controlled area has been described by following radiological parameters

  13. Evidence for Increased Aggressiveness in a Recent Widespread Strain of Puccinia striiformis f. sp. tritici Causing Stripe Rust of Wheat

    DEFF Research Database (Denmark)

    Milus, Eugene A; Kristensen, Kristian; Hovmøller, Mogens S

    2009-01-01

    Stripe rust (yellow rust) of wheat, caused by Puccinia striiformis f. sp. tritici, has become more severe in eastern United States, Australia, and elsewhere since 2000. Recent research has shown that this coincided with a global spread of two closely related strains that were similar based...... to the warm temperature regime for all variables. Based on these results and previously published models for stripe rust epidemics, recent severe stripe rust epidemics were most likely enhanced by the pathogen's increased aggressiveness, especially at higher temperature. Furthermore, these results demonstrate...... that wheat rust fungi can adapt to warmer temperatures and cause severe disease in previously unfavorable environments...

  14. Early osteological development of white perch and striped bass with emphasis on identification of their larvae. [Morone saxatilis; Morone americana

    Energy Technology Data Exchange (ETDEWEB)

    Fritzsche, R.A. (Univ. of Mississippi, University); Johnson, G.D.

    1980-07-01

    A cartilage and bone straining technique was employed to study the developmental osteology of the striped bass (Morone saxatilis) and white perch (Morone americana). Special attention was given to those osteological characters that appeared to be unique to the larvae of each species. Larval striped bass and white perch exhibited diagnostic differences in the position and shape of the median ethmoid, predorsal bones, dorsal- and anal-fin pterygiophores, vertebral column, and caudal skeleton. These differences were discernible at the earliest appearance of these elements as cartilage, and allow identification of striped bass and white perch larvae above a length of about 7.5 mm.

  15. Low complexity MIMO receivers

    CERN Document Server

    Bai, Lin; Yu, Quan

    2014-01-01

    Multiple-input multiple-output (MIMO) systems can increase the spectral efficiency in wireless communications. However, the interference becomes the major drawback that leads to high computational complexity at both transmitter and receiver. In particular, the complexity of MIMO receivers can be prohibitively high. As an efficient mathematical tool to devise low complexity approaches that mitigate the interference in MIMO systems, lattice reduction (LR) has been widely studied and employed over the last decade. The co-authors of this book are world's leading experts on MIMO receivers, and here they share the key findings of their research over years. They detail a range of key techniques for receiver design as multiple transmitted and received signals are available. The authors first introduce the principle of signal detection and the LR in mathematical aspects. They then move on to discuss the use of LR in low complexity MIMO receiver design with respect to different aspects, including uncoded MIMO detection...

  16. 76 FR 20835 - Amendment of VOR Federal Airways V-1, V-7, V-11 and V-20; Kona, HI

    Science.gov (United States)

    2011-04-14

    ...; Airspace Docket No. 10-AWP-20] Amendment of VOR Federal Airways V-1, V-7, V-11 and V-20; Kona, HI AGENCY..., HI; V-1, V-7, V-11 and V-20. The FAA is taking this action due to procedural changes requiring..., (76 FR 13082), amends VOR Federal Airways V-1, V-7 V-11 and V-20; Kona, HI. These VHF Omnidirectional...

  17. VG2 URA PWS RAW EXPERIMENT WAVEFORM 60MS V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set consists of electric field waveform samples from the Voyager 2 Plasma Wave Receiver waveform receiver obtained during the Uranus encounter. The...

  18. VG2 NEP PWS RAW EXPERIMENT WAVEFORM 60MS V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set consists of electric field waveform samples from the Voyager 2 Plasma Wave Receiver waveform receiver obtained during the Neptune encounter. The...

  19. Delphi Accounts Receivable Module -

    Data.gov (United States)

    Department of Transportation — Delphi accounts receivable module contains the following data elements, but are not limited to customer information, cash receipts, line of accounting details, bill...

  20. L-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for CaV1.2 mediated control of cochlear BDNF expression

    Directory of Open Access Journals (Sweden)

    Annalisa eZuccotti

    2013-08-01

    Full Text Available Voltage-gated L-type Ca2+ channels (L-VGCCs like CaV1.2 are assumed to play a crucial role for controlling release of trophic peptides including brain-derived neurotrophic factor (BDNF. In the inner ear of the adult mouse, beside the well described L-VGCC CaV1.3, also CaV1.2 is expressed. Due to lethality of constitutive CaV1.2 KO mice, the function of this ion channel as well as its putative relationship to BDNF in the auditory system is entirely elusive. We recently described that BDNF plays a differential role for inner hair cell (IHC vesicles release in normal and traumatized condition. To elucidate a presumptive role of CaV1.2 during this process, two tissue-specific conditional mouse lines were generated. To distinguish the impact of CaV1.2 on the cochlea from that on feedback loops from higher auditory centers CaV1.2 was deleted, in one mouse line, under the Pax2 promoter (CaV1.2Pax2 leading to a deletion in the spiral ganglion neurons (SGN, dorsal cochlear nucleus (DCN, and inferior colliculus (IC. In the second mouse line, the Egr2 promoter was used for deleting CaV1.2 (CaV1.2Egr2 in auditory brainstem nuclei. In both mouse lines normal hearing threshold and equal number of IHC release sites were observed. We found a slight reduction of auditory brainstem response (ABR wave I amplitudes in the CaV1.2Pax2 mice but not in the CaV1.2Egr2 mice. After noise exposure, CaV1.2Pax2 mice had less pronounced hearing loss that correlated with maintenance of ribbons in IHCs and less reduced activity in auditory nerve fibers, as well as in higher brain centers at supra-threshold sound stimulation. As reduced cochlear BDNF mRNA levels were found in CaV1.2Pax2 mice, we suggest that a CaV1.2 dependent step may participate in triggering part of the beneficial and deteriorating effects of cochlear BDNF in intact systems and during noise exposure through a pathway that is independent of Cav1.2 function in efferent circuits.

  1. Validity and Reliability of Adult ADHD Self-Report Scale Thai Version (ASRS-V1.1 TH)

    OpenAIRE

    KIATRUNGRIT, Komsan; PUTTHISRI, Suwannee; HONGSANGUANSRI, Sirichai; WISAJAN, Pattaraporn; JULLAGATE, Sudawan

    2017-01-01

    Background The adult ADHD Self–Report Scale Thai version (ASRS-V1.1) (18 items) is a questionnaire for screening adult ADHD. Aim To test the validity and reliability of the 18-question ASRS-V1.1 Thai version (ASRS-V1.1 TH) as a screening tool for adult ADHD Methods The original 18-question ASRS-V1.1 version was translated into Thai. The process was composed of forward-translation, synthesis of the translation, and back translation. Cross cultural adaptation, field testing, and final adjustmen...

  2. Outbursting Comet P/2010 V1 (Ikeya-Murakami): A Miniature Comet Holmes

    Science.gov (United States)

    Ishiguro, Masateru; Jewitt, David; Hanayama, Hidekazu; Usui, Fumihiko; Sekiguchi, Tomohiko; Yanagisawa, Kenshi; Kuroda, Daisuke; Yoshida, Michitoshi; Ohta, Kouji; Kawai, Nobuyuki; Miyaji, Takeshi; Fukushima, Hideo; Watanabe, Jun-ichi

    2014-05-01

    The short-period comet P/2010 V1 (Ikeya-Murakami, hereafter "V1") was discovered visually by two amateur astronomers. The appearance of the comet was peculiar, consisting of an envelope, a spherical coma near the nucleus and a tail extending in the anti-solar direction. We investigated the brightness and the morphological development of the comet by taking optical images with ground-based telescopes. Our observations show that V1 experienced a large-scale explosion between UT 2010 October 31 and November 3. The color of the comet was consistent with the Sun (g' - R C = 0.61 ± 0.20, R C - I C = 0.20 ± 0.20, and B - R C = 0.93 ± 0.25), suggesting that dust particles were responsible for the brightening. We used a dynamical model to understand the peculiar morphology, and found that the envelope consisted of small grains (0.3-1 μm) expanding at a maximum speed of 500 ± 40 m s-1, while the tail and coma were composed of a wider range of dust particle sizes (0.4-570 μm) and expansion speeds 7-390 m s-1. The total mass of ejecta is ~5 × 108 kg and kinetic energy ~5 × 1012 J. These values are much smaller than in the historic outburst of 17P/Holmes in 2007, but the energy per unit mass (1 × 104 J kg-1) is comparable. The energy per unit mass is about 10% of the energy released during the crystallization of amorphous water ice suggesting that crystallization of buried amorphous ice can supply the mass and energy of the outburst ejecta.

  3. Serotonin Decreases the Gain of Visual Responses in Awake Macaque V1.

    Science.gov (United States)

    Seillier, Lenka; Lorenz, Corinna; Kawaguchi, Katsuhisa; Ott, Torben; Nieder, Andreas; Pourriahi, Paria; Nienborg, Hendrikje

    2017-11-22

    Serotonin, an important neuromodulator in the brain, is implicated in affective and cognitive functions. However, its role even for basic cortical processes is controversial. For example, in the mammalian primary visual cortex (V1), heterogenous serotonergic modulation has been observed in anesthetized animals. Here, we combined extracellular single-unit recordings with iontophoresis in awake animals. We examined the role of serotonin on well-defined tuning properties (orientation, spatial frequency, contrast, and size) in V1 of two male macaque monkeys. We find that in the awake macaque the modulatory effect of serotonin is surprisingly uniform: it causes a mainly multiplicative decrease of the visual responses and a slight increase in the stimulus-selective response latency. Moreover, serotonin neither systematically changes the selectivity or variability of the response, nor the interneuronal correlation unexplained by the stimulus ("noise-correlation"). The modulation by serotonin has qualitative similarities with that for a decrease in stimulus contrast, but differs quantitatively from decreasing contrast. It can be captured by a simple additive change to a threshold-linear spiking nonlinearity. Together, our results show that serotonin is well suited to control the response gain of neurons in V1 depending on the animal's behavioral or motivational context, complementing other known state-dependent gain-control mechanisms. SIGNIFICANCE STATEMENT Serotonin is an important neuromodulator in the brain and a major target for drugs used to treat psychiatric disorders. Nonetheless, surprisingly little is known about how it shapes information processing in sensory areas. Here we examined the serotonergic modulation of visual processing in the primary visual cortex of awake behaving macaque monkeys. We found that serotonin mainly decreased the gain of the visual responses, without systematically changing their selectivity, variability, or covariability. This

  4. Outbursting comet P/2010 V1 (Ikeya-Murakami): A miniature comet Holmes

    Energy Technology Data Exchange (ETDEWEB)

    Ishiguro, Masateru [Department of Physics and Astronomy, Seoul National University, Gwanak, Seoul 151-742 (Korea, Republic of); Jewitt, David [Department of Earth, Planetary and Space Sciences, University of California at Los Angeles, 595 Charles Young Drive East, Los Angeles, CA 90095-1567 (United States); Hanayama, Hidekazu; Miyaji, Takeshi; Fukushima, Hideo; Watanabe, Jun-ichi [Ishigakijima Astronomical Observatory, National Astronomical Observatory of Japan, Ishigaki, Okinawa 907-0024 (Japan); Usui, Fumihiko [Department of Astronomy, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Sekiguchi, Tomohiko [Department of Teacher Training, Hokkaido University of Education, 9 Hokumon, Asahikawa 070-8621 (Japan); Yanagisawa, Kenshi; Kuroda, Daisuke [Okayama Astrophysical Observatory, National Astronomical Observatory of Japan, Asaguchi, Okayama 719-0232 (Japan); Yoshida, Michitoshi [Hiroshima Astrophysical Science Center, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Ohta, Kouji [Department of Astronomy, Kyoto University, Kyoto 606-8502 (Japan); Kawai, Nobuyuki [Department of Physics, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan)

    2014-05-20

    The short-period comet P/2010 V1 (Ikeya-Murakami, hereafter {sup V}1{sup )} was discovered visually by two amateur astronomers. The appearance of the comet was peculiar, consisting of an envelope, a spherical coma near the nucleus and a tail extending in the anti-solar direction. We investigated the brightness and the morphological development of the comet by taking optical images with ground-based telescopes. Our observations show that V1 experienced a large-scale explosion between UT 2010 October 31 and November 3. The color of the comet was consistent with the Sun (g' – R {sub C} = 0.61 ± 0.20, R {sub C} – I {sub C} = 0.20 ± 0.20, and B – R {sub C} = 0.93 ± 0.25), suggesting that dust particles were responsible for the brightening. We used a dynamical model to understand the peculiar morphology, and found that the envelope consisted of small grains (0.3-1 μm) expanding at a maximum speed of 500 ± 40 m s{sup –1}, while the tail and coma were composed of a wider range of dust particle sizes (0.4-570 μm) and expansion speeds 7-390 m s{sup –1}. The total mass of ejecta is ∼5 × 10{sup 8} kg and kinetic energy ∼5 × 10{sup 12} J. These values are much smaller than in the historic outburst of 17P/Holmes in 2007, but the energy per unit mass (1 × 10{sup 4} J kg{sup –1}) is comparable. The energy per unit mass is about 10% of the energy released during the crystallization of amorphous water ice suggesting that crystallization of buried amorphous ice can supply the mass and energy of the outburst ejecta.

  5. Tackling Bet v 1 and associated food allergies with a single hybrid protein.

    Science.gov (United States)

    Hofer, Heidi; Asam, Claudia; Hauser, Michael; Nagl, Birgit; Laimer, Josef; Himly, Martin; Briza, Peter; Ebner, Christof; Lang, Roland; Hawranek, Thomas; Bohle, Barbara; Lackner, Peter; Ferreira, Fátima; Wallner, Michael

    2017-08-01

    Allergy vaccines should be easily applicable, safe, and efficacious. For Bet v 1-mediated birch pollen and associated food allergies, a single wild-type allergen does not provide a complete solution. We aimed to combine immunologically relevant epitopes of Bet v 1 and the 2 clinically most important related food allergens from apple and hazelnut to a single hybrid protein, termed MBC4. After identification of T cell epitope-containing parts on each of the 3 parental allergens, the hybrid molecule was designed to cover relevant epitopes and evaluated in silico. Thereby a mutation was introduced into the hybrid sequence, which should alter the secondary structure without compromising the immunogenic properties of the molecule. MBC4 and the parental allergens were purified to homogeneity. Analyses of secondary structure elements revealed substantial changes rendering the hybrid de facto nonreactive with patients' serum IgE. Nevertheless, the protein was monomeric in solution. MBC4 was able to activate T-cell lines from donors with birch pollen allergy and from mice immunized with the parental allergens. Moreover, on immunization of mice and rabbits, MBC4 induced cross-reactive IgG antibodies, which were able to block the binding of human serum IgE. Directed epitope rearrangements combined with a knowledge-based structural modification resulted in a protein unable to bind IgE from allergic patients. Still, properties to activate specific T cells or induce blocking antibodies were conserved. This suggests that MBC4 is a suitable vaccine candidate for the simultaneous treatment of Bet v 1 and associated food allergies. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  6. Population Genetics of red striped mullet (Mullus surmuletus in Turkish Seas Based on Mitochondrial and Nuclear DNA data

    Directory of Open Access Journals (Sweden)

    Fevzi Bardakci

    2014-07-01

    This study was determined a preview of genetic structure of red striped mullet because of few sampling localities so a further study is would be useful to determine its population structure along its distribution area in detail.

  7. Technological quality, mineral profile, and sensory attributes of broiler chicken breasts affected by White Striping and Wooden Breast myopathies.

    Science.gov (United States)

    Tasoniero, G; Cullere, M; Cecchinato, M; Puolanne, E; Dalle Zotte, A

    2016-11-01

    The aim of the research was to study the impact of white striping and wooden breast myopathies on the technological quality, mineral, and sensory profile of poultry meat. With this purpose, a total of 138 breasts were selected for a control group with normal breasts (N), a group of breasts characterised by white striping (WS) myopathy, and a group of breasts having both white striping and wooden breast myopathies (WSWB). Data revealed that the simultaneous presence of the two myopathies, with respect to the WS lesion individually considered, had a further detrimental effect on pH (6.04 vs. 5.96; P white striping and wooden breast myopathies. © 2016 Poultry Science Association Inc.

  8. Identification and mapping of leaf, stem and stripe rust resistance quantitative trait loci and their interactions in durum wheat

    OpenAIRE

    Singh, A.; Pandey, M. P.; Singh, A. K.; Knox, R. E.; Ammar, K.; Clarke, J. M.; Clarke, F. R.; Singh, R. P.; Pozniak, C. J.; DePauw, R. M.; McCallum, B. D.; Cuthbert, R. D.; Randhawa, H. S.; Fetch, T. G.

    2012-01-01

    Leaf rust (Puccinia triticina Eriks.), stripe rust (Puccinia striiformis f. tritici Eriks.) and stem rust (Puccinia graminis f. sp. tritici) cause major production losses in durum wheat (Triticum turgidum L. var. durum). The objective of this research was to identify and map leaf, stripe and stem rust resistance loci from the French cultivar Sachem and Canadian cultivar Strongfield. A doubled haploid population from Sachem/Strongfield and parents were phenotyped for seedling reaction to leaf ...

  9. Race-Specific Adult-Plant Resistance in Winter Wheat to Stripe Rust and Characterization of Pathogen Virulence Patterns.

    Science.gov (United States)

    Milus, Eugene A; Moon, David E; Lee, Kevin D; Mason, R Esten

    2015-08-01

    Stripe rust, caused by Puccinia striiformis f. sp. tritici, is an important disease of wheat in the Great Plains and southeastern United States. Growing resistant cultivars is the preferred means for managing stripe rust, but new virulence in the pathogen population overcomes some of the resistance. The objectives of this study were to characterize the stripe rust resistance in contemporary soft and hard red winter wheat cultivars, to characterize the virulence of P. striiformis f. sp. tritici isolates based on the resistances found in the cultivars, and to determine wheat breeders' perceptions on the importance and methods for achieving stripe rust resistance. Seedlings of cultivars were susceptible to recent isolates, indicating they lacked effective all-stage resistance. However, adult-plants were resistant or susceptible depending on the isolate, indicating they had race-specific adult-plant resistance. Using isolates collected from 1990 to 2013, six major virulence patterns were identified on adult plants of twelve cultivars that were selected as adult-plant differentials. Race-specific adult-plant resistance appears to be the only effective type of resistance protecting wheat from stripe rust in eastern United States. Among wheat breeders, the importance of incorporating stripe rust resistance into cultivars ranged from high to low depending on the frequency of epidemics in their region, and most sources of stripe rust resistance were either unknown or already overcome by virulence in the pathogen population. Breeders with a high priority for stripe rust resistance made most of their selections based on adult-plant reactions in the field, whereas breeders with a low priority for resistance based selections on molecular markers for major all-stage resistance genes.

  10. [Prediction model of meteorological grade of wheat stripe rust in winter-reproductive area, Sichuan Basin, China].

    Science.gov (United States)

    Guo, Xiang; Wang, Ming Tian; Zhang, Guo Zhi

    2017-12-01

    The winter reproductive areas of Puccinia striiformis var. striiformis in Sichuan Basin are often the places mostly affected by wheat stripe rust. With data on the meteorological condition and stripe rust situation at typical stations in the winter reproductive area in Sichuan Basin from 1999 to 2016, this paper classified the meteorological conditions inducing wheat stripe rust into 5 grades, based on the incidence area ratio of the disease. The meteorological factors which were biologically related to wheat stripe rust were determined through multiple analytical methods, and a meteorological grade model for forecasting wheat stripe rust was created. The result showed that wheat stripe rust in Sichuan Basin was significantly correlated with many meteorological factors, such as the ave-rage (maximum and minimum) temperature, precipitation and its anomaly percentage, relative humidity and its anomaly percentage, average wind speed and sunshine duration. Among these, the average temperature and the anomaly percentage of relative humidity were the determining factors. According to a historical retrospective test, the accuracy of the forecast based on the model was 64% for samples in the county-level test, and 89% for samples in the municipal-level test. In a meteorological grade forecast of wheat stripe rust in the winter reproductive areas in Sichuan Basin in 2017, the prediction was accurate for 62.8% of the samples, with 27.9% error by one grade and only 9.3% error by two or more grades. As a result, the model could deliver satisfactory forecast results, and predicate future wheat stripe rust from a meteorological point of view.

  11. Multilayer graphene electro-absorption optical modulator based on double-stripe silicon nitride waveguide.

    Science.gov (United States)

    Fan, Meiyong; Yang, Huimin; Zheng, Pengfei; Hu, Guohua; Yun, Binfeng; Cui, Yiping

    2017-09-04

    A graphene electro-absorption optical modulator based on double-stripe silicon nitride waveguide is proposed and analyzed. By embedding four graphene layers in the double-stripe silicon nitride waveguide and the graphene layers co-electrode design, the total metal-graphene contact resistance can be reduced 50% and as high as 30.6GHz modulation bandwidth can be achieved theoretically. The calculated extinction ratio and figure of merit are 0.1658dB/um and 9.7, respectively. And the required switching voltage from its minimum to maximum absorption state is 3.8180V and 780.50fJ/bit power consuming can be achieved. The proposed modulator can remedy the lack of high speed modulator on the passive silicon nitride waveguide.

  12. Effect of an electric field on the properties of BN Möbius stripes

    Energy Technology Data Exchange (ETDEWEB)

    Lemos de Melo, J. [Departamento de Física, CCEN, Universidade Federal da Paraíba, Caixa Postal 5008, 58051-900 João Pessoa, PB (Brazil); Azevedo, S., E-mail: sazevedo@fisica.ufpb.br [Departamento de Física, CCEN, Universidade Federal da Paraíba, Caixa Postal 5008, 58051-900 João Pessoa, PB (Brazil); Kaschny, J.R. [Instituto Federal da Bahia, Campus Vitória da Conquista, Av. Amazonas 3150, 45075-265 Vitória da conquista, BA (Brazil)

    2014-09-15

    In the present work, we present a first-principles study on the effects of an external electric field on the structural stability and electronic properties of boron nitride Möbius stripes with armchair and zigzag chirality. The calculation results indicate that the gap energy can be remarkably reduced by the application of an external field. Such reduction is in principle attributed to the occurrence of Stark effect, which significance depends on the orientation of the applied field relative to the stripe axis. Moreover, the electric field produces significant changes on dipole momentum of the structure and induces a negative shift on the calculated total energy, reducing the obtained formation energy. - Highlights: • The gap energy is remarkably reduced by the application of an external field. • The electric field produces significant changes on dipole momentum. • The field induces a negative shift on the total energy due to Stark effect.

  13. On fast iterative mapping algorithms for stripe based coarse-grained reconfigurable architectures

    Science.gov (United States)

    Mehta, Gayatri; Patel, Krunalkumar; Pollard, Nancy S.

    2015-01-01

    Reconfigurable devices have potential for great flexibility/efficiency, but mapping algorithms onto these architectures is a long-standing challenge. This paper addresses this challenge for stripe based coarse-grained reconfigurable architectures (CGRAs) by drawing on insights from graph drawing. We adapt fast, iterative algorithms from hierarchical graph drawing to the problem of mapping to stripe based architectures. We find that global sifting is 98 times as fast as simulated annealing and produces very compact designs with 17% less area on average, at a cost of 5% greater wire length. Interleaving iterations of Sugiyama and global sifting is 40 times as fast as simulated annealing and achieves somewhat more compact designs with 1.8% less area on average, at a cost of only 1% greater wire length. These solutions can enable fast design space exploration, rapid performance testing, and flexible programming of CGRAs "in the field."

  14. Pigment cell interactions and differential xanthophore recruitment underlying zebrafish stripe reiteration and Danio pattern evolution.

    Science.gov (United States)

    Patterson, Larissa B; Bain, Emily J; Parichy, David M

    2014-11-06

    Fishes have diverse pigment patterns, yet mechanisms of pattern evolution remain poorly understood. In zebrafish, Danio rerio, pigment-cell autonomous interactions generate dark stripes of melanophores that alternate with light interstripes of xanthophores and iridophores. Here, we identify mechanisms underlying the evolution of a uniform pattern in D. albolineatus in which all three pigment cell classes are intermingled. We show that in this species xanthophores differentiate precociously over a wider area, and that cis regulatory evolution has increased expression of xanthogenic Colony Stimulating Factor-1 (Csf1). Expressing Csf1 similarly in D. rerio has cascading effects, driving the intermingling of all three pigment cell classes and resulting in the loss of stripes, as in D. albolineatus. Our results identify novel mechanisms of pattern development and illustrate how pattern diversity can be generated when a core network of pigment-cell autonomous interactions is coupled with changes in pigment cell differentiation.

  15. Effect of the tiger stripes on the deformation of Saturn's moon Enceladus

    Science.gov (United States)

    Souček, Ondřej; Hron, Jaroslav; Běhounková, Marie; Čadek, Ondřej

    2016-07-01

    Enceladus is a small icy moon of Saturn with active jets of water emanating from fractures around the south pole, informally called tiger stripes, which might be connected to a subsurface water ocean. The effect of these features on periodic tidal deformation of the moon has so far been neglected because of the difficulties associated with implementation of faults in continuum mechanics models. Here we estimate the maximum possible impact of the tiger stripes on tidal deformation and heat production within Enceladus's ice shell by representing them as narrow zones with negligible frictional and bulk resistance passing vertically through the whole ice shell. Assuming a uniform ice shell thickness of 25 km, consistent with the recent estimate of libration, we demonstrate that the faults can dramatically change the distribution of stress and strain in Enceladus's south polar region, leading to a significant increase of the heat production in this area.

  16. Responsiveness of the major birch allergen Bet v 1 scaffold to the gastric environment: Impact on structure and allergenic activity

    DEFF Research Database (Denmark)

    Sancho, Ana I; Wangorsch, Andrea; Jensen, Bettina M

    2011-01-01

    Four Bet v 1 homologous food allergens from celeriac (rApi g 1), apple (rMal d 1), peach (rPru p 1) and hazelnut (rCor a 1), were used to probe the structural responsiveness of the Bet v 1 scaffold to gastric digestion conditions and its impact on allergenicity....

  17. Complete nucleotide sequence of little cherry virus 1 (LChV-1) infecting sweet cherry in China

    Science.gov (United States)

    Little cherry virus 1 (LChV-1), associated with little cherry disease (LCD), has a significant impact on fruit quality of infected sweet cherry trees. We report the full genome sequence of an isolate of LChV-1 from China, detected by small RNA deep sequencing and amplified by overlapping RT-PCR. The...

  18. Probing rotational relaxation in HBr (v=1) using double resonance spectroscopy.

    Science.gov (United States)

    Kabir, Md Humayun; Antonov, Ivan O; Heaven, Michael C

    2009-02-21

    Rotational energy transfer in HBr(v=1)+HBr collisions has been investigated using an optical pump-probe double resonance technique at ambient temperature. Rotationally state selective excitation of v=1 for rotational levels in the range J=0-9 was achieved by stimulated Raman pumping, and the evolution of population was monitored using (2+1) resonantly enhanced multiphoton ionization spectroscopy of the g (3) summation (-)-X (1) summation (+)(0-1) band. Collision-induced population transfer events with DeltaJ

  19. FahamecV1:A Low Cost Automated Metaphase Detection System

    Directory of Open Access Journals (Sweden)

    H. Yilmaz

    2017-12-01

    Full Text Available In this study, FahamecV1 is introduced and investigated as a low cost and high accuracy solution for metaphase detection. Chromosome analysis is performed at the metaphase stage and high accuracy and automated detection of the metaphase stage plays an active role in decreasing analysis time. FahamecV1 includes an optic microscope, a motorized microscope stage, an electronic control unit, a camera, a computer and a software application. Printing components of the motorized microscope stage (using a 3D printer is of the main reasons for cost reduction. Operations such as stepper motor calibration, are detection, focusing, scanning, metaphase detection and saving of coordinates into a database are automatically performed. To detect metaphases, a filter named Metafilter is developed and applied. Average scanning time per preparate is 77 sec/cm2. True positive rate is calculated as 95.1%, true negative rate is calculated as 99.0% and accuracy is calculated as 98.8%.

  20. Patients with oral allergic syndrome to apple have intense proliferative response to BET V 1.

    Science.gov (United States)

    Ciprandi, G; Fenoglio, G; Kalli, F; De Amici, M; Leonardi, S; Miraglia Del Giudice, M; Salpietro, C; La Rosa, M; Caimmi, S; Marseglia, G L

    2012-01-01

    Patients with pollen allergy may frequently present an additional food-related allergy (Oral Allergic Syndrome, OAS), as consequence of cross-reactivity between pollen allergens (mainly birch, hazelnut, alder, mugwort) and vegetable allergens. The aim of this study was to evaluate the effect on Bet v 1-induced T cell proliferation exerted by the presence of OAS in birch patients. Fourteen allergic patients were evaluated (6 males, mean age 35.8 years). All of them were monosensitized to birch and suffered from allergic rhinitis: 4 had also OAS to apple. Proliferation of peripheral mononuclear cells was evaluated using Bet v 1 and non-specific stimuli. OAS had higher proliferation than non-OAS patients. In addition, there were significant relationships between immunological and clinical parameters in OAS patients. This study evidences that OAS characterizes a more severe form of birch allergy: as OAS patients had higher SI, circulating eosinophils, and IgE levels. Thus, this study confirms the previous report and underlines the relevance of measuring recombinant birch allergen as higher values may suggest a reliable prediction of OAS.

  1. Experience-Dependent Synaptic Plasticity in V1 Occurs without Microglial CX3CR1.

    Science.gov (United States)

    Schecter, Rachel W; Maher, Erin E; Welsh, Christina A; Stevens, Beth; Erisir, Alev; Bear, Mark F

    2017-11-01

    Brief monocular deprivation (MD) shifts ocular dominance and reduces the density of thalamic synapses in layer 4 of the mouse primary visual cortex (V1). We found that microglial lysosome content is also increased as a result of MD. Previous studies have shown that the microglial fractalkine receptor CX3CR1 is involved in synaptic development and hippocampal plasticity. We therefore tested the hypothesis that neuron-to-microglial communication via CX3CR1 is an essential component of visual cortical development and plasticity in male mice. Our data show that CX3CR1 is not required for normal development of V1 responses to visual stimulation, multiple forms of experience-dependent plasticity, or the synapse loss that accompanies MD in layer 4. By ruling out an essential role for fractalkine signaling, our study narrows the search for understanding how microglia respond to active synapse modification in the visual cortex. SIGNIFICANCE STATEMENT Microglia in the visual cortex respond to monocular deprivation with increased lysosome content, but signaling through the fractalkine receptor CX3CR1 is not an essential component in the mechanisms of visual cortical development or experience-dependent synaptic plasticity. Copyright © 2017 the authors 0270-6474/17/3710541-13$15.00/0.

  2. Theoretical and experimental investigations of efficient light coupling with spatially varied all dielectric striped waveguides

    Science.gov (United States)

    Yilmaz, Y. A.; Tandogan, S. E.; Hayran, Z.; Giden, I. H.; Turduev, M.; Kurt, H.

    2017-07-01

    Integrated photonic systems require efficient, compact, and broadband solutions for strong light coupling into and out of optical waveguides. The present work investigates an efficient optical power transferring the problem between optical waveguides having different widths of in/out terminals. We propose a considerably practical and feasible concept to implement and design an optical coupler by introducing gradually index modulation to the coupler section. The index profile of the coupler section is modulated with a Gaussian function by the help of striped waveguides. The effective medium theory is used to replace the original spatially varying index profile with dielectric stripes of a finite length/width having a constant effective refractive index. 2D and 3D finite-difference time-domain analyzes are utilized to investigate the sampling effect of the designed optical coupler and to determine the parameters that play a crucial role in enhancing the optical power transfer performance. Comparing the coupling performance of conventional benchmark adiabatic and butt couplers with the designed striped waveguide coupler, the corresponding coupling efficiency increases from approximately 30% to 95% over a wide frequency interval. In addition, to realize the realistic optical coupler appropriate to integrated photonic applications, the proposed structure is numerically designed on a silicon-on-insulator wafer. The implemented SOI platform based optical coupler operates in the telecom wavelength regime (λ = 1.55 μm), and the dimensions of the striped coupler are kept as 9.77 μm (along the transverse to propagation direction) and 7.69 μm (along the propagation direction) where the unit distance is fixed to be 465 nm. Finally, to demonstrate the operating design principle, the microwave experiments are conducted and the spot size conversion ratio as high as 7.1:1 is measured, whereas a coupling efficiency over 60% in the frequency range of 5.0-16.0 GHz has been also

  3. Familiarity breeds contempt: effects of striped skunk color, shape, and abundance on wild carnivore behavior

    OpenAIRE

    Jennifer S. Hunter

    2009-01-01

    Multicomponent aposematic warning signals are generally accepted to function as a deterrent to predatory attacks; however, the relative importance of specific visual cues used by wild predators to recognize defended animals is poorly understood. Here, I use naturally and reciprocally colored taxidermy models of striped skunks (Mephitis mephitis) and gray foxes (Urocyon cinereoargenteus) to explore the impact of aposematic coloration and body shape on the behavior of wild mammalian predators. ...

  4. Effective genes for resistance to stripe rust and virulence of Puccinia ...

    African Journals Online (AJOL)

    The results revealed that stripe rust resistance genes Yr3, Yr5, Yr10, Yr15, Yr26, YrSP and YrCV were resistant, while Yr18 showed moderate susceptibility at all locations. Genes YrA-, Yr2, Yr6, Yr7, Yr8, Yr9, Yr17, Yr27 and gene combinations Opata (Yr27+Yr18) and Super Kauz (Yr9, Yr27, Yr18) were found susceptible.

  5. Species Profiles: Life Histories and Environmental Requirements of Coastal Fishes and Invertebrates (South Atlantic). Striped Bass

    Science.gov (United States)

    1989-12-01

    the sides (Werner 1980). Osteological vomer and paiatines (Hardy 1978). differences are also evident in the three species (Woolcott 1957; Harrell 1984...Percichthyidae) by means of osteological patterns, meristics and Holland, B.F., Jr., and G.F. Yelverton. 1973. morphometrics. Ph.D. Dissertation. Uni...1957. Comparative osteology Striped Bass Subcommittee of the House of of serranid fishes of the genus Roccus Representatives. 9 pp. (Mitchill). Copeia

  6. Tiger Stripes and Cassini ISS High-Resolution Imaging of Enceladus

    Science.gov (United States)

    Helfenstein, Paul; Denk, T.; Giese, B.; McEwen, A. S.; Neukum, G.; Perry, J.; Porco, C. C.; Thomas, P. C.; Turtle, E.; Verbiscer, A.; Veverka, J.

    2008-09-01

    Deciphering the mechanisms of Enceladus’ plumes is one of the most important and challenging tasks for planetary science. Cassini has provided a wealth of data by remote and in-situ data collection, but fundamental details of the vents and their context remain elusive. Three flybys of Enceladus by Cassini in 2008, on August 11 (altitude: 50km), October 9 (30km), and October 31 (200 km) are designed to further our knowledge of Enceladus’ geology and geophysics. Anticipated data include images as good as 7 m/pixel of parts of the geologically active South Polar Terrain (SPT). We targeted six different known eruption sites (Spitale and Porco 2007, Nature 449, 695-697) along Cairo Sulcus, Baghdad Suclus, and Damascus Sulcus, as well as non-active portions of the the "tiger stripes" and bright grooved terrain in between. On each of the three flybys we also plan contiguous ISS broadband multi-spectral mosaics of the entire SPT region so that we can search for volcanically and tectonically driven temporal changes and construct detailed digital terrain maps. Previous images of the tiger stripes and other rift systems on Enceladus resolve geomorphic structures on hundred meter scales or larger. Within those resolution limits, tiger stripes are morphologically distinguished most strongly from comparably sized young looking rifts elsewhere on Enceladus by their prominent upturned flanks, the muted appearance of their surface relief, and their relative absence of distinct cliff faces, probably of solid ice along scarps. The anticipated new high-resolution images will provide critical structural details needed to identify the extent to which unique attributes of tiger stripes are caused by mantling by plume fallout, tectonic deformation, seismic disruption, or perhaps thermal processes. Here, we present a first analysis of the August 11 close flyby images.

  7. Cytogenetics and stripe rust resistance of wheat-Thinopyrum elongatum hybrid derivatives.

    Science.gov (United States)

    Li, Daiyan; Long, Dan; Li, Tinghui; Wu, Yanli; Wang, Yi; Zeng, Jian; Xu, Lili; Fan, Xing; Sha, Lina; Zhang, Haiqin; Zhou, Yonghong; Kang, Houyang

    2018-01-01

    Amphidiploids generated by distant hybridization are commonly used as genetic bridge to transfer desirable genes from wild wheat species into cultivated wheat. This method is typically used to enhance the resistance of wheat to biotic or abiotic stresses, and to increase crop yield and quality. Tetraploid Thinopyrum elongatum exhibits strong adaptability, resistance to stripe rust and Fusarium head blight, and tolerance to salt, drought, and cold. In the present study, we produced hybrid derivatives by crossing and backcrossing the Triticum durum-Th. elongatum partial amphidiploid ( Trititrigia 8801, 2 n  = 6 ×  = 42, AABBEE) with wheat cultivars common to the Sichuan Basin. By means of cytogenetic and disease resistance analyses, we identified progeny harboring alien chromosomes and measured their resistance to stripe rust. Hybrid progenies possessed chromosome numbers ranging from 40 to 47 (mean = 42.72), with 40.0% possessing 42 chromosomes. Genomic in situ hybridization revealed that the number of alien chromosomes ranged from 1 to 11. Out of the 50 of analyzed lines, five represented chromosome addition (2 n  = 44 = 42 W + 2E) and other five were chromosome substitution lines (2 n  = 42 = 40 W + 2E). Importantly, a single chromosome derived from wheat- Th. elongatum intergenomic Robertsonian translocations chromosome was occurred in 12 lines. Compared with the wheat parental cultivars ('CN16' and 'SM482'), the majority (70%) of the derivative lines were highly resistant to strains of stripe rust pathogen known to be prevalent in China. The findings suggest that these hybrid-derivative lines with stripe rust resistance could potentially be used as germplasm sources for further wheat improvement.

  8. Eliminating Vertical Stripe Defects on Silicon Steel Surface by L1/2 Regularization

    OpenAIRE

    Jing, Wenfeng; Meng, Deyu; Qiao, Chen; Peng, Zhiming

    2011-01-01

    The vertical stripe defects on silicon steel surface seriously affect the appearance and electromagnetic properties of silicon steel products. Eliminating such defects is adifficult and urgent technical problem. This paper investigates the relationship between the defects and their influence factors by classification methods. However, when the common classification methods are used in the problem, we cannot obtain a classifier with high accuracy. Byanalysis of the data set, we find that it is...

  9. Sustained eruptions on Enceladus explained by turbulent dissipation in tiger stripes

    Science.gov (United States)

    Kite, Edwin S.; Rubin, Allan M.

    2016-04-01

    Spacecraft observations suggest that the plumes of Saturn’s moon Enceladus draw water from a subsurface ocean, but the sustainability of conduits linking ocean and surface is not understood. Observations show eruptions from “tiger stripe” fissures that are sustained (although tidally modulated) throughout each orbit, and since the 2005 discovery of the plumes. Peak plume flux lags peak tidal extension by ˜1 rad, suggestive of resonance. Here, we show that a model of the tiger stripes as tidally flexed slots that puncture the ice shell can simultaneously explain the persistence of the eruptions through the tidal cycle, the phase lag, and the total power output of the tiger stripe terrain, while suggesting that eruptions are maintained over geological timescales. The delay associated with flushing and refilling of O(1)-m-wide slots with ocean water causes erupted flux to lag tidal forcing and helps to buttress slots against closure, while tidally pumped in-slot flow leads to heating and mechanical disruption that staves off slot freezeout. Much narrower and much wider slots cannot be sustained. In the presence of long-lived slots, the 106-y average power output of the tiger stripes is buffered by a feedback between ice melt-back and subsidence to O(1010) W, which is similar to observed power output, suggesting long-term stability. Turbulent dissipation makes testable predictions for the final flybys of Enceladus by Cassini. Our model shows how open connections to an ocean can be reconciled with, and sustain, long-lived eruptions. Turbulent dissipation in long-lived slots helps maintain the ocean against freezing, maintains access by future Enceladus missions to ocean materials, and is plausibly the major energy source for tiger stripe activity.

  10. Identification of a uniquely expanded V1R (ORA) gene family in the Japanese grenadier anchovy (Coilia nasus).

    Science.gov (United States)

    Zhu, Guoli; Tang, Wenqiao; Wang, Liangjiang; Wang, Cong; Wang, Xiaomei

    A number of studies have suggested that olfaction plays an important role in fish migration. Fish use several distinct families of olfactory receptors to detect environmental odorants, including MORs (main olfactory receptors), V1Rs (vomeronasal type-1 receptors), V2Rs (vomeronasal type-2 receptors), TAARs (trace amine-associated receptors), and FPRs (formyl peptide receptors). The V1Rs have been reported to detect pheromones, and a pheromone hypothesis for the spawning migration of anadromous fish has been proposed. Examining whether Coilia nasus relies on V1R-mediated olfaction for spawning migration is important for understanding the molecular basis of spawning migration behavior. Here, we explored the V1R gene family in anadromous C. nasus . Six V1R genes previously reported in other teleost fish were successfully identified. Interestingly, we detected the largest V1R repertoire in teleost fish from C. nasus and identified a species-specific expansion event of V1R3 gene that has previously been detected as single-copy genes in other teleost fish. The V1R loci were found to be populated with repetitive sequences, especially in the expanded V1R3 genes. Additionally, the divergence of V1R3 genetic structures in different populations of C. nasus indicates the copy number variation (CNV) in V1R3 gene among individuals of C. nasus . Most of the putative C. nasus V1R genes were expressed primarily in the olfactory epithelium, consistent with the role of the gene products as functional olfactory receptors. Significant differences in the expression levels of V1R genes were detected between the anadromous and non-anadromous C. nasus . This study represents a first step in the elucidation of the olfactory communication system of C. nasus at the molecular level. Our results indicate that some V1R genes may be involved in the spawning migration of C. nasus , and the study provides new insights into the spawning migration and genome evolution of C. nasus .

  11. Alexandrite Lidar Receiver

    National Research Council Canada - National Science Library

    Wilkerson, Thomas

    2000-01-01

    ...". The chosen vendor, Orca Photonics, In. (Redmond, WA), in close collaboration with USU personnel, built a portable, computerized lidar system that not only is suitable as a receiver for a near IR alexandrite laser, but also contains an independent Nd...

  12. JSSG - SPACED RECEIVER MEASUREMENTS.

    Science.gov (United States)

    The height of ionospheric irregularities was measured by several laboratories belonging to the Joint Satellite Studies Group, using spaced receiver techniques. The method of analysis and results obtained are presented. (Author)

  13. Solar energy receiver

    Science.gov (United States)

    Schwartz, Jacob

    1978-01-01

    An improved long-life design for solar energy receivers provides for greatly reduced thermally induced stress and permits the utilization of less expensive heat exchanger materials while maintaining receiver efficiencies in excess of 85% without undue expenditure of energy to circulate the working fluid. In one embodiment, the flow index for the receiver is first set as close as practical to a value such that the Graetz number yields the optimal heat transfer coefficient per unit of pumping energy, in this case, 6. The convective index for the receiver is then set as closely as practical to two times the flow index so as to obtain optimal efficiency per unit mass of material.

  14. Receiver Gain Modulation Circuit

    Science.gov (United States)

    Jones, Hollis; Racette, Paul; Walker, David; Gu, Dazhen

    2011-01-01

    A receiver gain modulation circuit (RGMC) was developed that modulates the power gain of the output of a radiometer receiver with a test signal. As the radiometer receiver switches between calibration noise references, the test signal is mixed with the calibrated noise and thus produces an ensemble set of measurements from which ensemble statistical analysis can be used to extract statistical information about the test signal. The RGMC is an enabling technology of the ensemble detector. As a key component for achieving ensemble detection and analysis, the RGMC has broad aeronautical and space applications. The RGMC can be used to test and develop new calibration algorithms, for example, to detect gain anomalies, and/or correct for slow drifts that affect climate-quality measurements over an accelerated time scale. A generalized approach to analyzing radiometer system designs yields a mathematical treatment of noise reference measurements in calibration algorithms. By treating the measurements from the different noise references as ensemble samples of the receiver state, i.e. receiver gain, a quantitative description of the non-stationary properties of the underlying receiver fluctuations can be derived. Excellent agreement has been obtained between model calculations and radiometric measurements. The mathematical formulation is equivalent to modulating the gain of a stable receiver with an externally generated signal and is the basis for ensemble detection and analysis (EDA). The concept of generating ensemble data sets using an ensemble detector is similar to the ensemble data sets generated as part of ensemble empirical mode decomposition (EEMD) with exception of a key distinguishing factor. EEMD adds noise to the signal under study whereas EDA mixes the signal with calibrated noise. It is mixing with calibrated noise that permits the measurement of temporal-functional variability of uncertainty in the underlying process. The RGMC permits the evaluation of EDA by

  15. Numerical investigation on thermal stratification and striping phenomena in various coolants

    International Nuclear Information System (INIS)

    Zumao Yang; Muramatsu, Toshiharu

    2000-02-01

    It is important to study thermal stratification and striping phenomena for they can induce thermal fatigue failure of structures. This presentation uses the AQUA code, which has been developed in Japan Nuclear Cycle Development Institute (JNC), to investigate the characteristics of these thermal phenomena in water, liquid sodium, liquid lead and carbon dioxide gas. There are altogether eight calculated cases with same Richardson number and initial inlet hot velocity in thermal stratification calculations, in which four cases have same velocity difference between inlet hot and cold fluid, the other four cases with same temperature difference. The calculated results show: (1) The fluid's properties and initial conditions have considerable effects on thermal stratification, which is decided by the combination of such as thermal conduction, viscous dissipation and buoyant force, etc., and (2) The gas has distinctive thermal stratification characteristics from those of liquid because for horizontal flow in the transportation of momentum and energy, the drastic exchange usually happens at the hot-cold interface for liquid, however, the buoyancy and natural convection make the quick exchange position depart from the hot-cold interface for gas. In thermal striping analysis, only the first step work has been finished. The calculated results show: (1) the vertical flow has some difference in thermal stratification characteristics from those of horizontal flow, and (2) For deep thermal striping analysis in the calculated area, more attention should be paid to the center area along Z-direction for liquid and small velocity area for gas. (author)

  16. Aleutian Disease: An Emerging Disease in Free-Ranging Striped Skunks (Mephitis mephitis) From California.

    Science.gov (United States)

    LaDouceur, E E B; Anderson, M; Ritchie, B W; Ciembor, P; Rimoldi, G; Piazza, M; Pesti, D; Clifford, D L; Giannitti, F

    2015-11-01

    Aleutian disease virus (ADV, Amdovirus, Parvoviridae) primarily infects farmed mustelids (mink and ferrets) but also other fur-bearing animals and humans. Three Aleutian disease (AD) cases have been described in captive striped skunks; however, little is known about the relevance of AD in free-ranging carnivores. This work describes the pathological findings and temporospatial distribution in 7 cases of AD in free-ranging striped skunks. All cases showed neurologic disease and were found in a 46-month period (2010-2013) within a localized geographical region in California. Lesions included multisystemic plasmacytic and lymphocytic inflammation (ie, interstitial nephritis, myocarditis, hepatitis, meningoencephalitis, pneumonia, and splenitis), glomerulonephritis, arteritis with or without fibrinoid necrosis in several organs (ie, kidney, heart, brain, and spleen), splenomegaly, ascites/hydrothorax, and/or encephalomalacia with cerebral microangiopathy. ADV infection was confirmed in all cases by specific polymerase chain reaction and/or in situ hybridization. The results suggest that AD is an emerging disease in free-ranging striped skunks in California. © The Author(s) 2014.

  17. Pathogen dynamics and morbidity of striped skunks in the absence of rabies.

    Science.gov (United States)

    Gehrt, Stanley D; Kinsel, Michael J; Anchor, Chris

    2010-04-01

    Parasites have the potential to influence the population dynamics of mammalian hosts, either as a single devastating pathogen or as a community effect. Striped skunks (Mephitis mephitis) are typically host to rabies, which often regulates population numbers. We assessed micro- and macroparasite dynamics in striped skunk populations in the absence of rabies, to determine if a single pathogen, or community, was responsible for a majority of skunk deaths. We monitored mortality due to pathogens, and prevalence of pathogens via serology and necropsy, in two populations of striped skunks in northern Illinois during 1998-2004. Transmissible pathogens requiring direct transmission (i.e., canine distemper virus, canine parvovirus) exhibited high annual variability in prevalence. In contrast, those pathogens employing a more indirect, environmental route of transmission (i.e., Leptospira interrogans and Toxoplasma gondii) appeared to exhibit relatively less annual variability in prevalence. Skunks were diagnosed with infections from an average of 4.08 (SD=2.52, n=32) species of endoparasites, with a range of 1-11. Macroparasite prevalence and intensity did not vary among seasons, or sex or age of host. Severe infections occurred with multiple parasite species, and patterns of aggregation suggested some parasite species, or more likely the parasite community, act as a limiting mechanism in skunk populations.

  18. Summer habitat selection by striped bass, Morone Saxatilis, in Cherokee Reservoir, Tennessee, 1977

    Energy Technology Data Exchange (ETDEWEB)

    Waddle, H.R.; Coutant, C.C.; Wilson, J.L.

    1980-02-01

    Summer habitat selection patterns of 18 adult striped bass (Morone saxatilis) in Cherokee Reservoir were monitored with externally attached temperature-sensing acoustic or radio transmitters from June through September 1977. Mortalities of adult striped bass in this reservoir were hypothesized to be related to high summer temperatures and low dissolved oxygen (DO). The inhabited areas or refuges differed from noninhabited areas by maintaining temperatures less than or equal to 22 C and DO concentrations greater than 5 mg/liter. Total water hardness, pH, and water transparency were not significantly different among refuges and noninhabited areas. Movement of fish outside refuges occurred more frequently and for longer periods during June when the summer pattern of high temperatures and low DO was less severe. Fish experienced temperatures between 15 and 27 C with mean temperatures of individuals ranging from 18.5 to 22.0 C. Several tagged fish migrated outside the refuges and selected the lowest available temperature, generally near 21 C, even though DO concentrations at these temperatures were 3 mg/liter or less. Long-term survival of tagged and nontagged fish outside refuges was undetermined because no fish were tracked outside a refuge for more than 12 days without being lost. This study indicates that temperature strongly influences the behavior of striped bass and that adults of this species may have a thermal preferendum of approximately 21 C.

  19. Eliminating Vertical Stripe Defects on Silicon Steel Surface by L1/2 Regularization

    Directory of Open Access Journals (Sweden)

    Wenfeng Jing

    2011-01-01

    Full Text Available The vertical stripe defects on silicon steel surface seriously affect the appearance and electromagnetic properties of silicon steel products. Eliminating such defects is adifficult and urgent technical problem. This paper investigates the relationship between the defects and their influence factors by classification methods. However, when the common classification methods are used in the problem, we cannot obtain a classifier with high accuracy. Byanalysis of the data set, we find that it is imbalanced and inconsistent. Because the common classification methods are based on accuracy-maximization criterion, they are not applicable to imbalanced and inconsistent data set. Thus, we propose asupport-degree-maximization criterion and anovel cost-sensitive loss function and also establish an improved L1/2 regularization approach for solution of the problem. Moreover, by employing reweighted iteration gradient boosting algorithm, we obtain a linear classifier with a high support degree. Through analyzing the classifier, we formulate a rule under which the silicon steel vertical stripe defects do not occur in the existing production environment. By applying the proposed rule to 50TW600 silicon steel production, the vertical stripe defects of the silicon steel products have been greatly decreased.

  20. Stripes developed at the strong limit of nematicity in FeSe film

    Science.gov (United States)

    Li, Wei; Zhang, Yan; Deng, Peng; Xu, Zhilin; Mo, S.-K.; Yi, Ming; Ding, Hao; Hashimoto, M.; Moore, R. G.; Lu, D.-H.; Chen, Xi; Shen, Z.-X.; Xue, Qi-Kun

    2017-10-01

    A single monolayer of iron selenide grown on strontium titanate shows an impressive enhancement of superconductivity compared with the bulk, as well as a novel Fermi surface topology, extreme two-dimensionality, and the possibility of phonon-enhanced electron pairing. For films thicker than one unit cell, however, the electronic structure is markedly different, with a drastically suppressed superconductivity and strong nematicity appearing. The physics driving this extraordinary dichotomy of superconducting behaviour is far from clear. Here, we use low-temperature scanning tunnelling microscopy to study multilayers of iron selenide grown by molecular beam epitaxy, and find a stripe-type charge ordering instability that develops beneath the nematic state. The charge ordering is visible and pinned in the vicinity of impurities. And as it emerges in the strong limit of nematicity, it suggests that a magnetic fluctuation with a rather small wavevector may be competing with the ordinary collinear antiferromagnetic ordering in multilayer films. The existence of stripes in iron-based superconductors, which resemble the stripe order in cuprates, not only suggests that electronic anisotropy and correlation are playing an important role, but also provides a platform for probing the complex interactions between nematicity, charge ordering, magnetism and superconductivity in high-temperature superconductors.

  1. Reduction of Uncorrelated Striping Noise—Applications for Hyperspectral Pushbroom Acquisitions

    Directory of Open Access Journals (Sweden)

    Christian Rogass

    2014-11-01

    Full Text Available Hyperspectral images are of increasing importance in remote sensing applications. Imaging spectrometers provide semi-continuous spectra that can be used for physics based surface cover material identification and quantification. Preceding radiometric calibrations serve as a basis for the transformation of measured signals into physics based units such as radiance. Pushbroom sensors collect incident radiation by at least one detector array utilizing the photoelectric effect. Temporal variations of the detector characteristics that differ with foregoing radiometric calibration cause visually perceptible along-track stripes in the at-sensor radiance data that aggravate succeeding image-based analyses. Especially, variations of the thermally induced dark current dominate and have to be reduced. In this work, a new approach is presented that efficiently reduces dark current related stripe noise. It integrates an across-effect gradient minimization principle. The performance has been evaluated using artificially degraded whiskbroom (reference and real pushbroom acquisitions from EO-1 Hyperion and AISA DUAL that are significantly covered by stripe noise. A set of quality indicators has been used for the accuracy assessment. They clearly show that the new approach outperforms a limited set of tested state-of-the-art approaches and achieves a very high accuracy related to ground-truth for selected tests. It may substitute recent algorithms in the Reduction of Miscalibration Effects (ROME framework that is broadly used to reduce radiometric miscalibrations of pushbroom data takes.

  2. Locomotion Enhances Neural Encoding of Visual Stimuli in Mouse V1.

    Science.gov (United States)

    Dadarlat, Maria C; Stryker, Michael P

    2017-04-05

    Neurons in mouse primary visual cortex (V1) are selective for particular properties of visual stimuli. Locomotion causes a change in cortical state that leaves their selectivity unchanged but strengthens their responses. Both locomotion and the change in cortical state are thought to be initiated by projections from the mesencephalic locomotor region, the latter through a disinhibitory circuit in V1. By recording simultaneously from a large number of single neurons in alert mice viewing moving gratings, we investigated the relationship between locomotion and the information contained within the neural population. We found that locomotion improved encoding of visual stimuli in V1 by two mechanisms. First, locomotion-induced increases in firing rates enhanced the mutual information between visual stimuli and single neuron responses over a fixed window of time. Second, stimulus discriminability was improved, even for fixed population firing rates, because of a decrease in noise correlations across the population. These two mechanisms contributed differently to improvements in discriminability across cortical layers, with changes in firing rates most important in the upper layers and changes in noise correlations most important in layer V. Together, these changes resulted in a threefold to fivefold reduction in the time needed to precisely encode grating direction and orientation. These results support the hypothesis that cortical state shifts during locomotion to accommodate an increased load on the visual system when mice are moving. SIGNIFICANCE STATEMENT This paper contains three novel findings about the representation of information in neurons within the primary visual cortex of the mouse. First, we show that locomotion reduces by at least a factor of 3 the time needed for information to accumulate in the visual cortex that allows the distinction of different visual stimuli. Second, we show that the effect of locomotion is to increase information in cells of all

  3. Head-to-head comparison of PI-RADS v2 and PI-RADS v1.

    Science.gov (United States)

    Polanec, Stephan; Helbich, Thomas H; Bickel, Hubert; Pinker-Domenig, Katja; Georg, Dietmar; Shariat, Shahrokh F; Aulitzky, Wolfgang; Susani, Martin; Baltzer, Pascal A

    2016-06-01

    To compare the reproducibility and diagnostic performance of PI-RADS version 2 (v2) and version 1 (v1) for the diagnosis of prostate cancer (PCa) on multiparametric MRI. This IRB-approved retrospective study included 65 consecutive biopsy-naïve or biopsy-negative patients suspicious for PCa (mean age: 65 years, mean PSA: 10.8ng/ml) who were undergoing MR-guided biopsy after multiparametric 3T prostate MRI (T2w, DWI, DCE). Two independent readers (R1; R2) scored the prostate lesions according to the v2 score and the v1 sum score. Diagnostic measures (sensitivity, specificity, and area under the ROC-curve) were compared for all cases and stratified by location (transitional zone, TZ, peripheral zone, PZ). Inter-reader agreement was assessed by kappa statistics. Inter reader agreement for v2 and v1 was substantial to almost perfect (kappa v2: 0.71, v1: 0.81). Overall, sensitivity between both readers and methods did not differ (p>0.05). Overall specificity was higher using v1 compared to v2 (R1: p=0.0078, R2: p=0.0313) In the TZ, v2 showed a higher AUC (0.81-0.84) compared to v1 (AUC 0.77-0.78). Here, the sensitivity of v2 (87.5-100%) was higher than that of v1 (75%) while v2 specificity (50%-56.3%) was lower than that of v1 (68.8-75%). In the PZ, AUCs were higher using v1 (AUC 0.82-0.83) compared to v2 (AUC 0.61-0.63). The specificity for v1 was higher (43.8-62.3%) than that for v2 (12.5-18.8%) while both v2 and v1 achieved 100% sensitivity. PI-RADS v2 and v1 inter-reader agreement is excellent, but their diagnostic performance differs. While v2 appears to be the preferable method for the evaluation of TZ lesions, v1 performs better in the PZ. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. Implications of white striping and wooden breast abnormalities on quality traits of raw and marinated chicken meat.

    Science.gov (United States)

    Mudalal, S; Lorenzi, M; Soglia, F; Cavani, C; Petracci, M

    2015-04-01

    One of the consequences of intense genetic selection for growth of poultry is the recent appearance of abnormalities in chicken breast muscles, such as white striping (characterised by superficial white striations) and wooden breast (characterised by pale and bulged areas with substantial hardness). The aim of this study was to evaluate the quality traits of chicken fillets affected by white striping and wooden breast abnormalities. In two replications, 192 fillets were divided into the following four classes: normal (n=48; absence of any visual defects), white striping (n=48, presence of white striations), wooden breast (n=48; diffusely presence of hardened areas) and white striping/wooden breast (n=48; fillets affected by both abnormalities). Morphology, raw meat texture and technological properties were assessed in both unprocessed (pH, colour, drip loss, cooking loss and cooked meat shear force) and marinated meat (marinade uptake, purge loss, cooking loss and cooked meat shear force). Fillets affected by white striping, wooden breast or both abnormalities exhibited higher breast weights compared with normal fillets (305.5, 298.7, 318.3 and 244.7 g, respectively; Pmeat hardness compared with both normal and the white striping abnormality, for which there was no difference. Overall, the occurrence of the individual and combined white striping and wooden breast abnormalities resulted in substantial reduction in the quality of breast meat, although these abnormalities are associated with distinct characteristics. Wooden breast fillets showed lower marinade uptake and higher cooking losses than white-striped fillets for both unprocessed and marinated meats. On the other hand, white-striped fillets showed a moderate decline in marinade and cooking yield. Fillets affected by both abnormalities had the highest (Pmeat, drip loss, purge loss and cooked meat shear force were negligible or relatively low and of little practical importance. Thus, the presence of white

  5. Hematologic and plasma chemistry RIs for cultured Striped catfish (Pangasius hypophthalmus) in recirculating aquaculture systems.

    Science.gov (United States)

    Galagarza, Oscar A; Kuhn, David D; Smith, Stephen A; Hrubec, Terry C

    2017-09-01

    Striped catfish (Pangasius hypophthalmus) is a valuable aquaculture fish species produced primarily in Southeast Asia. In the United States, it is bred as an ornamental species. Striped catfish has high productivity and great demand in numerous countries around the world, yet little is known about its normal physiology. The objective of this study was to establish hematologic and blood chemistry RIs for healthy juvenile Striped catfish. Blood samples were collected from 70 Striped catfish raised in recirculating aquaculture systems. Whole blood and plasma samples were analyzed for multiple hematologic and chemistry variables using standard techniques. The RIs for hematology were as follows: PCV 23.5-35.9%, MCV 106.3-156.6 fL, RBC count 1.79-2.75 × 10 6 cells/μL, thrombocytes 26,318-73,333 cells/μL, total WBC count 36,294-94,286 cells/μL, total lymphocytes 18,997-59,998 cells/μL, small lymphocytes 13,763-51,490 cells/μL, large lymphocytes 715-21,200 cells/μL, granulocytes 4504-18,291 cells/μL, and monocytes 0-7549 cells/μL. Plasma chemistry RIs were the following: ALP 32.7-74.6 U/L, AST 20.3-1235.8 U/L, sodium 135.2-147.7 mmol/L, potassium 3.3-5.0 mmol/L, chloride 120.1-133.6 mmol/L, calcium 2.7-3.6 mmol/L, magnesium 0.9-1.3 mmol/L, phosphorous 1.4-2.7 mmol/L, glucose 4.6-7.6 mmol/L, cholesterol 2.8-5.3 mmol/L, total protein 30-42 g/L, albumin 7-11 g/L, globulin 22-32 g/L, albumin:globulin ratio 0.27-0.37, creatinine 0-8 μmol/L, and osmolality 251.8-327.9 mOsm/kg. Reference intervals reported here can help veterinarians and fish health specialists monitor the health status of Striped catfish under recirculating aquaculture conditions for research, exhibition, and production purposes. © 2017 American Society for Veterinary Clinical Pathology.

  6. The working out of a design rule in case of structures submitted to thermal striping

    International Nuclear Information System (INIS)

    Lejeail, Y.

    1994-01-01

    Thermal striping is a complex phenomenon involving incomplete mixing of hot and cold jets of fluid near a component surface, thus submitted to random fast temperature fluctuations. Because of his nature, the zones where thermal striping can occur in a fast breeder reactor are well known; these areas can suffer fatigue damage. It has been studied by several authors and some thermomechanical design rules against this fatigue damage have been proposed. In the french point of view, the problem is the determination of the margin between the mean and the design strain controlled fatigue curves, giving the allowable maximum temperature range that a component can sustain during his life without crack initiation. The purpose of this paper is the presentation of literature results (particularly on uniaxial smooth specimens) concerning the effects of different factors such as surface finish, environment, weldments, ageing, scatter of fatigue results, prior high strain cycling...on the high temperature fatigue life, which are of first importance for the determination of design factors in case of thermal striping. The remaining question is the combination of these factors. For the analysis of thermal striping test results, it is of great interest and importance to compare the crack initiation cycles and to use a coherent strain for uniaxial and equibiaxial fatigue results, as we show in the interpretation of FAENA and SPLASH tests (performed respectively by Y. Bergamaschi and B. Marini). An analysis based on elastic calculations as proposed in the RCCMR design code gives a good correlation, despite the ambiguous choice of some coefficients in best fit analysis. This problem disappears entirely in case of high cycles/low temperature variations. Then we present a strategy for the accomplishment of simplified thermal striping tests on the FAENA sodium loop in view of acquiring a better design factor knowledge. With this experimental program, we intend to study the interaction of

  7. 'Chaos' in superregenerative receivers

    International Nuclear Information System (INIS)

    Commercon, Jean-Claude; Badard, Robert

    2005-01-01

    The superregenerative principle has been known since the early 1920s. The circuit is extremely simple and extremely sensitive. Today, superheterodyne receivers generally supplant superregenerative receivers in most applications because there are several undesirable characteristics: poor selectivity, reradiation, etc. Superregenerative receivers undergo a revival in recent papers for wireless systems, where low cost and very low power consumption are relevant: house/building meters (such as water, energy, gas counter), personal computer environment (keyboard, mouse), etc. Another drawback is the noise level which is higher than that of a well-designed superheterodyne receiver; without an antenna input signal, the output of the receiver hears in an earphone as a waterfall noise; this sound principally is the inherent input noise amplified and detected by the circuit; however, when the input noise is negligible with respect of an antenna input signal, we are faced to an other source of 'noise' self-generated by the superregenerative working. The main objective of this paper concerns this self-generated noise coming from an exponential growing followed by a re-injection process for which the final state is a function of the phase of the input signal

  8. Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

    Science.gov (United States)

    Lanfranchi, Elisa; Pavkov-Keller, Tea; Koehler, Eva-Maria; Diepold, Matthias; Steiner, Kerstin; Darnhofer, Barbara; Hartler, Jürgen; van den Bergh, Tom; Joosten, Henk-Jan; Gruber-Khadjawi, Mandana; Thallinger, Gerhard G.; Birner-Gruenberger, Ruth; Gruber, Karl; Winkler, Margit; Glieder, Anton

    2017-05-01

    Homology and similarity based approaches are most widely used for the identification of new enzymes for biocatalysis. However, they are not suitable to find truly novel scaffolds with a desired function and this averts options and diversity. Hydroxynitrile lyases (HNLs) are an example of non-homologous isofunctional enzymes for the synthesis of chiral cyanohydrins. Due to their convergent evolution, finding new representatives is challenging. Here we show the discovery of unique HNL enzymes from the fern Davallia tyermannii by coalescence of transcriptomics, proteomics and enzymatic screening. It is the first protein with a Bet v1-like protein fold exhibiting HNL activity, and has a new catalytic center, as shown by protein crystallography. Biochemical properties of D. tyermannii HNLs open perspectives for the development of a complementary class of biocatalysts for the stereoselective synthesis of cyanohydrins. This work shows that systematic integration of -omics data facilitates discovery of enzymes with unpredictable sequences and helps to extend our knowledge about enzyme diversity.

  9. CO (v = 1-0) emission in the molecular shock regions of OMC-1

    Science.gov (United States)

    Grasdalen, G. L.; Hackwell, John A.; Lynch, David K.; Russell, Ray W.

    1992-01-01

    Using the new Aerospace spectrometer on the Kuiper Airborne Observatory, we have obtained observations of the molecular shocks associated with OMC-1. Unexpectedly these observations reveal (b = 1-0) emission from CO at 4.6 microns superposed on a strong continuum. Our observations strongly suggest that both the emission feature and the continuum are produced in molecular shocks. Since the (v = 1-0) band of CO is only excited in high-velocity shocks, we may be observing for the first time the primary driving mechanism in these regions. Even if these features are produced by scattering, the characteristics will provide new constraints on the conditions in and the geometry of the shock regions.

  10. Experience with construction and assembly of V-1 nuclear power plant

    International Nuclear Information System (INIS)

    Prochazka, J.; Stepanek, S.; Drahy, J.

    1981-01-01

    The model is discussed of the constructions of the V-1 nuclear power plant at Jaslovske Bohunice with SKODA Trust fulfilling the role of the general supplier of the secondary part technology and the chief and special assembly contractor. The SKODA Trust mediated the Soviet supplies of technology, Soviet assembly and special assembly, and the mounting of the primary part according to Soviet projects. Plant start-up was safeguarded by the investor through Bohunice power plant staff and Soviet experts. The assembly of the primary circuit and the test assembly of reactor parts are described and the experience gained is discussed. The technological requirements are illustrated by the most important characteristics of the individual parts of the primary circuit. Also described are the design specifications of the 220 MW saturated steam turbine and the experience with its assembly and start-up. (B.S.)

  11. The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity.

    Science.gov (United States)

    Amaya, Fumimasa; Wang, Haibin; Costigan, Michael; Allchorne, Andrew J; Hatcher, Jon P; Egerton, Julie; Stean, Tania; Morisset, Valerie; Grose, David; Gunthorpe, Martin J; Chessell, Iain P; Tate, Simon; Green, Paula J; Woolf, Clifford J

    2006-12-13

    We used a mouse with deletion of exons 4, 5, and 6 of the SCN11A (sodium channel, voltage-gated, type XI, alpha) gene that encodes the voltage-gated sodium channel Na(v)1.9 to assess its contribution to pain. Na(v)1.9 is present in nociceptor sensory neurons that express TRPV1, bradykinin B2, and purinergic P2X3 receptors. In Na(v)1.9-/- mice, the non-inactivating persistent tetrodotoxin-resistant sodium TTXr-Per current is absent, whereas TTXr-Slow is unchanged. TTXs currents are unaffected by the mutation of Na(v)1.9. Pain hypersensitivity elicited by intraplantar administration of prostaglandin E2, bradykinin, interleukin-1beta, capsaicin, and P2X3 and P2Y receptor agonists, but not NGF, is either reduced or absent in Na(v)1.9-/- mice, whereas basal thermal and mechanical pain sensitivity is unchanged. Thermal, but not mechanical, hypersensitivity produced by peripheral inflammation (intraplanatar complete Freund's adjuvant) is substantially diminished in the null allele mutant mice, whereas hypersensitivity in two neuropathic pain models is unchanged in the Na(v)1.9-/- mice. Na(v)1.9 is, we conclude, an effector of the hypersensitivity produced by multiple inflammatory mediators on nociceptor peripheral terminals and therefore plays a key role in mediating peripheral sensitization.

  12. Central solar energy receiver

    Science.gov (United States)

    Drost, M. Kevin

    1983-01-01

    An improved tower-mounted central solar energy receiver for heating air drawn through the receiver by an induced draft fan. A number of vertically oriented, energy absorbing, fin-shaped slats are radially arranged in a number of concentric cylindrical arrays on top of the tower coaxially surrounding a pipe having air holes through which the fan draws air which is heated by the slats which receive the solar radiation from a heliostat field. A number of vertically oriented and wedge-shaped columns are radially arranged in a number of concentric cylindrical clusters surrounding the slat arrays. The columns have two mirror-reflecting sides to reflect radiation into the slat arrays and one energy absorbing side to reduce reradiation and reflection from the slat arrays.

  13. Wideband CMOS receivers

    CERN Document Server

    Oliveira, Luis

    2015-01-01

    This book demonstrates how to design a wideband receiver operating in current mode, in which the noise and non-linearity are reduced, implemented in a low cost single chip, using standard CMOS technology.  The authors present a solution to remove the transimpedance amplifier (TIA) block and connect directly the mixer’s output to a passive second-order continuous-time Σ∆ analog to digital converter (ADC), which operates in current-mode. These techniques enable the reduction of area, power consumption, and cost in modern CMOS receivers.

  14. Preliminary examination of the reliability and concurrent validity of the attention-deficit/hyperactivity disorder self-report scale v1.1 symptom checklist to rate symptoms of attention-deficit/hyperactivity disorder in adolescents.

    Science.gov (United States)

    Adler, Lenard A; Shaw, David M; Spencer, Thomas J; Newcorn, Jeffrey H; Hammerness, Paul; Sitt, David J; Minerly, Christina; Davidow, Jennifer V; Faraone, Stephen V

    2012-06-01

    To validate the attention-deficit/hyperactivity disorder (ADHD) Self-Report Scale (ASRS) v1.1 Symptom Checklist versus the clinician-administered ADHD Rating Scale (ADHD-RS) in adolescents with ADHD. A total of 88 adolescents with ADHD aged 13-17 years participated in the study. The study was completed in one or two visits, 1-9 weeks apart. At each visit, participants completed the ASRS v1.1 Symptom Checklist, after which raters administered the ADHD-RS. Internal consistency of the ASRS v1.1 Symptom Checklist was assessed by Cronbach's alpha (Cronbach's α). Concurrent validity between the scales was assessed using Pearson's correlation coefficients. Item-by-item reliability between the scales was assessed by the Kappa coefficient of agreement. The mean age of participants was 14.9±1.5 SD years. 76.1% (n=67) were male. 73.9% (n=65) were currently receiving medication for ADHD. Internal consistency of ASRS v1.1 Symptom Checklist items was high, with Cronbach's α coefficients of 0.93 at Visit 1 and 0.94 at Visit 2. Pearson's correlation coefficients between the ASRS v1.1 Symptom Checklist and ADHD-RS were highly significant at Visit 1 (r=0.72, pASRS v1.1 Symptoms Checklist showed high internal consistency and high concurrent validity with the clinician-administered ADHD-RS in adolescents with ADHD. Results of this study suggest that the ASRS v1.1 Symptom Checklist is an internally consistent self-report scale for the assessment of adolescent ADHD and is moderately associated with a concurrently administered clinician measure of ADHD symptoms.

  15. Assessing the Effects of Suomi NPP VIIRS M15/M16 Detector Radiometric Stability and Relative Spectral Response Variation on Striping

    Directory of Open Access Journals (Sweden)

    Zhuo Wang

    2016-02-01

    Full Text Available Modern satellite radiometers have many detectors with different relative spectral response (RSR. Effect of RSR differences on striping and the root cause of striping in sensor data record (SDR radiance and brightness temperature products have not been well studied. A previous study used MODTRAN radiative transfer model (RTM to analyze striping. In this study, we make efforts to find the possible root causes of striping. Line-by-Line RTM (LBLRTM is used to evaluate the effect of RSR difference on striping and the atmospheric dependency for VIIRS bands M15 and M16. The results show that previous study using MODTRAN is repeatable: the striping is related to the difference between band-averaged and detector-level RSR, and the BT difference has some atmospheric dependency. We also analyzed VIIRS earth view (EV data with several striping index methods. Since the EV data is complex, we further analyze the onboard calibration data. Analysis of Variance (ANOVA test shows that the noise along track direction is the major reason for striping. We also found evidence of correlation between solar diffuser (SD and blackbody (BB for detector 1 in M15. Digital Count Restoration (DCR and detector instability are possibly related to the striping in SD and EV data, but further analysis is needed. These findings can potentially lead to further SDR processing improvements.

  16. Sender-Receiver Games

    NARCIS (Netherlands)

    Peeters, R.J.A.P.; Potters, J.A.M.

    1999-01-01

    Standard game-theoretic solution concepts do not guarantee meaningful commu- nication in cheap-talk games. In this paper, we define a solution concept which guarantees communication for a large class of games by designing a behavior pro- tocol which the receiver uses to judge messages sent by the

  17. VG2 URA PWS RESAMPLED SUMMARY SPECTRUM ANALYZER 48SEC V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set consists of 48-second calibrated, averaged wave electric field intensities from the Voyager 2 Plasma Wave Receiver spectrum analyzer obtained in the...

  18. VG2 NEP PWS RESAMPLED SUMMARY SPECTRUM ANALYZER 48SEC V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set consists of 48-second calibrated, averaged wave electric field intensities from the Voyager 2 Plasma Wave Receiver spectrum analyzer obtained in the...

  19. VG2 NEP PWS EDITED RDR UNCALIB SPECTRUM ANALYZER 4SEC V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set consists of 4-second edited, wave electric field intensities from the Voyager 2 Plasma Wave Receiver (PWS) spectrum analyzer obtained in the vicinity...

  20. VEGA1 PUMA DUST MASS SPECTROMETER DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The PUMA data were submitted by IKI in two unique forms, a GROUPS FITS file and undocumented binary file. In one original form, the data in this set were received as...

  1. VEGA1 DUST MASS SPECTROMETER MODAL DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The data from MPI for this dataset were received as text files each containing spectra of a single instrument mode (there were several files for most modes). These...

  2. VEGA2 PUMA DUST MASS SPECTROMETER DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The data from IKI for this dataset were received as two binary files containing data taken in all instrument modes. These files were split into separate files for...

  3. VEGA2 PUMA DUST MASS SPECTROMETER MODAL DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The data from MPI for this dataset were received as text files each containing spectra of a single instrument mode (there were several files for most modes). These...

  4. LRO MOON MINI-RF 2/3/5 BISTATIC RADAR V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set contains radar data of the lunar surface from bistatic measurements utilizing the Aricebo Observatory transmitter and LRO Mini-RF receiver.

  5. VG2 URA PWS EDITED RDR UNCALIB SPECTRUM ANALYZER 4SEC V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set consists of 4-second edited, wave electric field intensities from the Voyager 2 Plasma Wave Receiver spectrum analyzer obtained in the vicinity of the...

  6. GO J PWS REFORMATTED PLAYBACK SPECTRUM ANALYZER FULL V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set includes full resolution electric and magnetic wave spectra from the Galileo plasma wave receiver recorded during Jupiter orbital operations. In...

  7. Evaluation of the I. Stage of decommissioning and implementation of the II. Stage of decommissioning of NPP V1

    International Nuclear Information System (INIS)

    Hrasnova, E.

    2015-01-01

    In this paper author deals with following aspects: 1. Introduction of company Nuclear and Decommissioning Company, plc; 2. Evaluation of the I. stage of decommissioning and implementation of the II. Stage of decommissioning of NPP V1; (author)

  8. Questioning the Specificity of ASRS-v1.1 to Accurately Detect ADHD in Substance Abusing Populations

    Science.gov (United States)

    Chiasson, Jean-Pierre; Stavro, Katherine; Rizkallah, Elie; Lapierre, Luc; Dussault, Maxime; Legault, Louis; Potvin, Stephane

    2012-01-01

    Objective: To assess the specificity of the Adult ADHD Self-Report Scale (ASRS-v1.1) in detecting ADHD among individuals with substance use disorders (SUDs). Method: A chart review of 183 SUD patients was conducted. Patients were screened for ADHD with the ASRS-v1.1 and were later assessed by a psychiatrist specialized in ADHD. Results: Among SUD…

  9. Simulations of corrosion product transfer with the OSCAR V1.2 code

    International Nuclear Information System (INIS)

    Dacquait, F.; Francescatto, J.; Broutin, F.; Genin, J.B.; Benier, G.; Girard, M.; You, D.; Ranchoux, G.; Bonnefon, J.; Bachet, M.; Riot, G.

    2012-09-01

    Activated Corrosion Products (ACPs) generate a radiation field in PWRs, which is the major contributor to the dose absorbed by nuclear power plant staff working during shutdown operations and maintenance. Therefore, a thorough understanding of the mechanisms that control the corrosion product transfer is of the highest importance. Since the 1970's, the R and D strategy in France has been based on experiments in test loops representative of PWR conditions, on in-situ gamma spectrometry measurements of the PWR primary system contamination and on simulation code development. The simulation of corrosion product transfers in PWR primary circuits is a major challenge since it involves many physical and chemical phenomena including: corrosion, dissolution, precipitation, erosion, deposition, convection, activation... In addition to the intrinsic difficulty of multi-physics modelling, the primary systems present severe operating conditions (300 deg. C, 150 bar, neutron flux, fluid velocity up to 15 m.s -1 and very low corrosion product concentrations). The purpose of the OSCAR code, developed by the CEA in cooperation with EDF and AREVA NP, is to predict the PWR primary system contamination by corrosion and fission products. The OSCAR code is considered to be not only a tool for numerical simulations and predictions (operational practices improvements and new-built PWRs design) but also one that might combine and organise all new knowledge useful to progress on contamination. The OSCAR code for Products of Corrosion, OSCAR PC, allows researchers to analyse the corrosion product behaviour and to calculate the ACP volume and surface activities of the primary and auxiliary systems. In the new version, OSCAR PC V1.2, the corrosion product transfer in the particulate form is enhanced and a new feature is the possibility to simulate cold shutdowns. In order to validate this version, the contamination transfer has been simulated in 5 French PWRs with different operating and

  10. Geomechanical characterisation of unsaturated Kunigel V1 bentonite: swelling and shear strength

    International Nuclear Information System (INIS)

    Yamamoto, S.; Shimura, T.; Asano, H.; Namiki, K.; Romero, E.; Kato, S.

    2012-01-01

    Document available in extended abstract form only. The development and validation of hydro-geomechanical models for bentonite buffer are one of the important subjects to appropriately evaluate long term behaviour of EBS in radioactive waste disposal. The Barcelona Basic Model (BBM), which is one extension of the modified Cam- Clay model for unsaturated and expansive soil, has been developed and widely applied to several hydro-geomechanical problems by using the coupled THM code, Code-Bright. Some advantages of the model are that hydro-geomechanical characteristics of buffer materials under saturated and partially saturated conditions are taken into account as well as the swelling characteristics due to wetting. Applicability of the BBM to consolidation and swelling behaviour of unsaturated bentonite has already been confirmed. In this study swelling characteristics of unsaturated bentonite are further discussed based on results from controlled-suction odometer tests, and in addition shear strength depending on matric suction is discussed based on controlled-suction triaxial compression tests. Swelling tests of compacted bentonite (Kunigel V1, initial dry density: 1.0 Mg/m 3 ) under constant confined vertical net stresses (20 and 100 kPa) were performed by using controlled-suction odometer cells. Matrice suction was stepwise reduced from 500 kPa to 0 kPa by 100 kPa. It is found that swelling is more dominant in latter step of the suction change (i.e., closer steps to saturation), especially the step from 100 kPa to 0 kPa. Swelling due to wetting, i.e. decrease in matric suction is defined in the BBM. Controlled-suction triaxial compression tests of compacted bentonite (Kunigel V1, initial dry density: 1.36 Mg/m 3 ) under both constant matric suctions (0, 300, and 500 kPa) and constant confined lateral net stresses were performed to study dependency of shear strength on matric suction. It is found that the apparent cohesion linearly increases with increase in matric

  11. The Support to Rural India's Public Education System (STRIPES) trial: a cluster randomised controlled trial of supplementary teaching, learning material and material support.

    Science.gov (United States)

    Lakshminarayana, Rashmi; Eble, Alex; Bhakta, Preetha; Frost, Chris; Boone, Peter; Elbourne, Diana; Mann, Vera

    2013-01-01

    The aim of the STRIPES trial was to assess the effectiveness of providing supplementary, remedial teaching and learning materials (and an additional 'kit' of materials for girls) on a composite of language and mathematics test scores for children in classes two, three and four in public primary schools in villages in the Nagarkurnool division of Andhra Pradesh, India. STRIPES was a cluster randomised trial in which 214 villages were allocated either to the supplementary teaching intervention (n = 107) or to serve as controls (n = 107). 54 of the intervention villages were further randomly allocated to receive additional kit for girls. The study was not blinded. Analysis was conducted on the intention to treat principle, allowing for clustering. Composite test scores were significantly higher in the intervention group (107 villages; 2364 children) than in the control group (106 villages; 2014 children) at the end of the trial (mean difference on a percentage scale 15.8; 95% CI 13.1 to 18.6; p<0.001; 0.75 Standard Deviation (SD) difference). Composite test scores were not significantly different in the 54 villages (614 girls) with the additional kits for girls compared to the 53 villages (636 girls) without these kits at the end of the trial (mean difference on a percentage scale 0.5; 95% CI -4.34 to 5.4; p = 0.84). The cost per 0.1 SD increase in composite test score for intervention without kits is Rs. 382.97 (£4.45, $7.13), and Rs.480.59 (£5.58, $8.94) for the intervention with kits. A 18 month programme of supplementary remedial teaching and learning materials had a substantial impact on language and mathematics scores of primary school students in rural Andhra Pradesh, yet providing a 'kit' of materials to girls in these villages did not lead to any measured additional benefit. Controlled-Trials.com ISRCTN69951502.

  12. Some effects of temperature, chlorine, and copper on the survival and growth of the coon stripe shrimp, Pandalus danae

    International Nuclear Information System (INIS)

    Gibson, C.I.; Thatcher, T.O.; Apts, C.W.

    1975-03-01

    The CTM (Critical Thermal Maxima) values for coon stripe shrimp increase with an increase in shrimp size. The CTM values for coon strip shrimp increase with an increase in the rate at which the temperature is elevated. Coon stripe shrimp are more resistant to chlorine when acclimated and exposed at 7.5 0 C-10 0 C than (a) when acclimated at 7.5 0 C and exposed at 15 0 C or 20 0 C, or when (b) acclimated and exposed at 15 0 C which is near their optimum short-term growth temperature (16 0 C). The optimal growing temperature for (1 to 7g) coon stripe shrimp for periods up to one month is 16 0 C. Copper at a concentration of 0.04 mg/l effectively retards the growth of (1-2g) coon stripe shrimp at 16 0 C over a one-month period. Chlorine at a concentration of 0.18 mg/l is lethal to (1-2g) coon stripe shrimp at 16 0 C and reduced their growth at 0.08 mg/l over a one-month period. (U.S.)

  13. Comparison of hematologic and serologic profiles of broiler birds with normal and severe degrees of white striping in breast fillets.

    Science.gov (United States)

    Kuttappan, V A; Huff, G R; Huff, W E; Hargis, B M; Apple, J K; Coon, C; Owens, C M

    2013-02-01

    White striping is the white striation occasionally observed parallel to the direction of muscle fibers in broiler breast fillets and thighs at the processing plant. Broiler breast fillets can be categorized as normal (NORM), moderate (MOD), or severe (SEV) based on the degree of white striping. Histologically, SEV fillets are characterized by the highest degree of degeneration of muscle fibers along with fibrosis and lipidosis when compared with NORM. The present study was undertaken to compare the hematologic and serologic profiles of broilers with NORM and SEV degrees of white striping to get more information on the systemic changes associated with the condition. Day-old male broiler chicks of a commercial strain were grown on the same diet in 6 replicate pens (n = 32 birds/pen). Blood samples (5 mL) were collected from the wing vein of each bird on the day before processing for analyzing hematologic and serologic profiles. At 63 d, the birds were weighed and processed in a commercial inline processing system. Weight of the butterfly fillets, liver, and abdominal fat pad were recorded. Left-side fillets were scored to obtain the degree of white striping for each bird. Representative samples for NORM (n = 24) and SEV (n = 17) categories were selected to compare the hematologic and serologic profiles. The SEV birds had greater (P white striping. The elevated serum enzyme levels confirm the muscle damage associated with the degenerative myopathy in SEV birds.

  14. Alternative Splicing of L-type CaV1.2 Calcium Channels: Implications in Cardiovascular Diseases

    Directory of Open Access Journals (Sweden)

    Zhenyu Hu

    2017-11-01

    Full Text Available L-type CaV1.2 calcium channels are the major pathway for Ca2+ influx to initiate the contraction of smooth and cardiac muscles. Alteration of CaV1.2 channel function has been implicated in multiple cardiovascular diseases, such as hypertension and cardiac hypertrophy. Alternative splicing is a post-transcriptional mechanism that expands CaV1.2 channel structures to modify function, pharmacological and biophysical property such as calcium/voltage-dependent inactivation (C/VDI, or to influence its post-translational modulation by interacting proteins such as Galectin-1. Alternative splicing has generated functionally diverse CaV1.2 isoforms that can be developmentally regulated in the heart, or under pathophysiological conditions such as in heart failure. More importantly, alternative splicing of certain exons of CaV1.2 has been reported to be regulated by splicing factors such as RNA-binding Fox-1 homolog 1/2 (Rbfox 1/2, polypyrimidine tract-binding protein (PTBP1 and RNA-binding motif protein 20 (RBM20. Understanding how CaV1.2 channel function is remodelled in disease will provide better information to guide the development of more targeted approaches to discover therapeutic agents for cardiovascular diseases.

  15. QR in V1--an ECG sign associated with right ventricular strain and adverse clinical outcome in pulmonary embolism.

    Science.gov (United States)

    Kucher, Nils; Walpoth, Nazan; Wustmann, Kerstin; Noveanu, Markus; Gertsch, Marc

    2003-06-01

    To test the hypothesis that Qr in V(1)is a predictor of pulmonary embolism, right ventricular strain, and adverse clinical outcome. ECG's from 151 patients with suspected pulmonary embolism were blindly interpreted by two observers. Echocardiography, troponin I, and pro-brain natriuretic peptide levels were obtained in 75 patients with pulmonary embolism. Qr in V(1)(14 vs 0 in controls; p or =1 mV (15 vs 1 in controls; p=0.0002) were more frequently present in patients with pulmonary embolism. Sensitivity and specificity of Qr in V(1)and T wave inversion in V(2)for predicting right ventricular dysfunction were 31/97% and 45/94%, respectively. Three of five patients who died in-hospital and 11 of 20 patients with a complicated course, presented with Qr in V(1). After adjustment for right ventricular strain including ECG, echocardiography, pro-brain natriuretic peptide and troponin I levels, Qr in V(1)(OR 8.7, 95%CI 1.4-56.7; p=0.02) remained an independent predictor of adverse outcome. Among the ECG signs seen in patients with acute pulmonary embolism, Qr in V(1)is closely related to the presence of right ventricular dysfunction, and is an independent predictor of adverse clinical outcome.

  16. Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.

    Science.gov (United States)

    Gorman, Jason; Soto, Cinque; Yang, Max M; Davenport, Thaddeus M; Guttman, Miklos; Bailer, Robert T; Chambers, Michael; Chuang, Gwo-Yu; DeKosky, Brandon J; Doria-Rose, Nicole A; Druz, Aliaksandr; Ernandes, Michael J; Georgiev, Ivelin S; Jarosinski, Marissa C; Joyce, M Gordon; Lemmin, Thomas M; Leung, Sherman; Louder, Mark K; McDaniel, Jonathan R; Narpala, Sandeep; Pancera, Marie; Stuckey, Jonathan; Wu, Xueling; Yang, Yongping; Zhang, Baoshan; Zhou, Tongqing; Mullikin, James C; Baxa, Ulrich; Georgiou, George; McDermott, Adrian B; Bonsignori, Mattia; Haynes, Barton F; Moore, Penny L; Morris, Lynn; Lee, Kelly K; Shapiro, Lawrence; Mascola, John R; Kwong, Peter D

    2016-01-01

    Broadly neutralizing antibodies (bNAbs) against HIV-1 Env V1V2 arise in multiple donors. However, atomic-level interactions had previously been determined only with antibodies from a single donor, thus making commonalities in recognition uncertain. Here we report the cocrystal structure of V1V2 with antibody CH03 from a second donor and model Env interactions of antibody CAP256-VRC26 from a third donor. These V1V2-directed bNAbs used strand-strand interactions between a protruding antibody loop and a V1V2 strand but differed in their N-glycan recognition. Ontogeny analysis indicated that protruding loops develop early, and glycan interactions mature over time. Altogether, the multidonor information suggested that V1V2-directed bNAbs form an 'extended class', for which we engineered ontogeny-specific antigens: Env trimers with chimeric V1V2s that interacted with inferred ancestor and intermediate antibodies. The ontogeny-based design of vaccine antigens described here may provide a general means for eliciting antibodies of a desired class.

  17. Chemical modification of Art v 1, a major mugwort pollen allergen, by cis-aconitylation and citraconylation

    Directory of Open Access Journals (Sweden)

    DRAGANA STANIĆ

    2009-04-01

    Full Text Available Art v 1 is the major allergen of mugwort (Artemisia vulgaris pollen, a significant cause of hay fever all over Europe. Specific immunotherapy is the only treatment modality for allergic disease. Application of modified allergens makes the treatment safer and more efficient. In this work, two out of three (citraconic anhydride, cis-aconitic anhydride, 2,3-dimethylmaleic anhydride tested anhydrides were proven to be suitable for chemical modifications of allergens. Art v 1 was modified by cis-aconitylation and citraconylation in order to obtain derivatives of Art v 1 that may be suitable for further immunological testing. Acylation of Art v 1 gave derivatives (caaArt v 1 and citArt v 1 with about 80 % modified amino groups. The derivatives were in the monomeric form and had dramatically reduced pI values. Both derivatives were relatively stable at neutral pH values, while the acyl groups undergo hydrolysis under acidic conditions. Modification of allergens by cis-aconitylation and citraconylation could be a new tool for obtaining allergoids.

  18. An outline of functional self-organization in V1: synchrony, STLR and Hebb rules.

    Science.gov (United States)

    Wright, J J; Bourke, P D

    2008-06-01

    A model of self-organization of synapses in the striate cortex is described, and its functional implications discussed. Principal assumptions are: (a) covariance of cell firing declines with distance in cortex, (b) covariance of stimulus characteristics declines with distance in the visual field, and (c) metabolic rates are approximately uniform in all small axonal segments. Under these constraints, Hebbian learning implies a maximally stable synaptic configuration corresponding to anatomically and physiologically realistic ''local maps'', each of macro-columnar size, and each organized as Möbius projections of a "global map" of retinotopic form. Convergence to the maximally stable configuration is facilitated by the spatio-temporal learning rule. A tiling of V1, constructed of approximately mirror-image reflections of each local map by its neighbors, is formed. The model supplements standard concepts of feed-forward visual processing by introducing a new basis for contextual modulation and neural network identifications of visual signals, as perturbation of the synaptic configuration by rapid stimulus transients. On a long time-scale, synaptic development could overwrite the Möbius configuration, while LTP and LTD could mediate synaptic gain on intermediate time-scales.

  19. [Implementation of the COBAS Taqman HIV-1 Test, v1.0 for vertical transmission diagnosis].

    Science.gov (United States)

    Castro, Gonzalo M; Sosa, María P; Gallego, Sandra V; Sicilia, Paola; Marin, Ángeles L; Altamirano, Natalia; Kademian, Silvia; Barbás, María G; Cudolá, Analía

    2015-01-01

    Vertical transmission is the main route of HIV infection in childhood. Because of the persistence of maternal HIV antibodies, virologic assays that directly detect HIV are required to diagnose HIV infection in infants younger than 18 months of age. The sensitivity of HIV RNA/DNA assays increases as the child becomes older. These tests have specificity values greater than 95%. The aim of this study was to evaluate the performance of the COBAS Taqman HIV-1 Test, v1.0 assay (Roche) and its concordance with a Multiplex Nested-PCR. Of 341 samples processed, 15 were positive and 326 negative by both methods. Sensitivity and specificity overall values for the viral load assay were 88.2% and 100%, respectively. Our results indicate that the COBAS Taqman assay evaluated could be used as an alternative method to diagnose HIV congenital infection. Copyright © 2014 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. Versican V1 Overexpression Induces a Myofibroblast-Like Phenotype in Cultured Fibroblasts.

    Directory of Open Access Journals (Sweden)

    Jon M Carthy

    Full Text Available Versican, a chondroitin sulphate proteoglycan, is one of the key components of the provisional extracellular matrix expressed after injury. The current study evaluated the hypothesis that a versican-rich matrix alters the phenotype of cultured fibroblasts.The full-length cDNA for the V1 isoform of human versican was cloned and the recombinant proteoglycan was expressed in murine fibroblasts. Versican expression induced a marked change in fibroblast phenotype. Functionally, the versican-expressing fibroblasts proliferated faster and displayed enhanced cell adhesion, but migrated slower than control cells. These changes in cell function were associated with greater N-cadherin and integrin β1 expression, along with increased FAK phosphorylation. The versican-expressing fibroblasts also displayed expression of smooth muscle α-actin, a marker of myofibroblast differentiation. Consistent with this observation, the versican fibroblasts displayed increased synthetic activity, as measured by collagen III mRNA expression, as well as a greater capacity to contract a collagen lattice. These changes appear to be mediated, at least in part, by an increase in active TGF-β signaling in the versican expressing fibroblasts, and this was measured by phosphorylation and nuclear accumulation of SMAD2.Collectively, these data indicate versican expression induces a myofibroblast-like phenotype in cultured fibroblasts.

  1. Analytical and experimental verification of confinement upgrading for Bohunice NPP V1

    International Nuclear Information System (INIS)

    Tkac, A.

    2000-01-01

    The scope of this paper is to provide a brief description of confinement improvement for NPP V-1 and supporting thermal-hydraulic analyses and experimental results. Series of analyses are performed in the process of the designing of an improved confinement system. Based on the analytical results obtained in the PHARE Project NS01/91 'Confinement and Improved ECCS Evaluation' as well as on additional activities performed after its finishing, additional modifications have been proposed during the designing. It is required to minimize the construction works EWST ceiling, while final solution shall fulfil acceptance criteria set forth in Decision 1/94 of Slovak Regulatory Authority (UJD). The technical requirement of the UJD is related to confinement. IAEA recommendations are taken into account. Due to new definitions of DBA and BDBA first considerations were connected and oriented on possible value of pressure peak increasing. As a result of the structural analysis limiting values for hermetic zone are determined. Some design modifications of the hermetic zone are proposed

  2. Vibrational relaxation of trapped molecules in solid matrices: OH(A 2Sigma+; v = 1)/Ar.

    Science.gov (United States)

    Ree, J; Kim, Y H; Shin, H K

    2009-01-07

    The vibrational relaxation of OH(A (2)Sigma(+);v=1) embedded in solid Ar has been studied over 4-80 K. The interaction model is based on OH undergoing local motions in a cage formed by a face-centered cubic stacking where the first shell atoms surround the guest and connect it to the heat bath through 12 ten-atom chains. The motions confined to the cage are the local translation and libration-rotation of OH and internal vibrations in OH...Ar, their energies being close to or a few times the energies of nearby first shell and chain atoms. The cage dynamics are studied by solving the equations of motion for the interaction between OH and first shell atoms, while energy propagation to the bulk phase through lattice chains is treated in the Langevin dynamics. Calculated energy transfer data are used in semiclassical procedure to obtain rate constants. In the early stage of interaction, OH transfers its energy to libration-rotation intramolecularily and then to the vibrations of the first shell and chain atoms on the time scale of several picoseconds. Libration-to-rotational transitions dispense the vibrational energy in small packages comparable to the lattice frequencies for ready flow. Energy propagation from the chains to the heat bath takes place on a long time scale of 10 ns or longer. Over the solid argon temperature range, the rate constant is on the order of 10(6) s(-1) and varies weakly with temperature.

  3. Crypt neurons express a single V1R-related ora gene.

    Science.gov (United States)

    Oka, Yuichiro; Saraiva, Luis R; Korsching, Sigrun I

    2012-03-01

    Both ciliated and microvillous olfactory sensory neuron populations express large families of olfactory receptor genes. However, individual neurons generally express only a single receptor gene according to the "one neuron-one receptor" rule. We report here that crypt neurons, the third type of olfactory neurons in fish species, use an even more restricted mode of expression. We recently identified a novel olfactory receptor family of 6 highly conserved G protein-coupled receptors, the v1r-like ora genes. We show now that a single member of this family, ora4 is expressed in nearly all crypt neurons, whereas the other 5 ora genes are not found in this cell type. Consistent with these findings, ora4 is never coexpressed with any of the remaining 5 ora genes. Furthermore, several lines of evidence indicate the absence of any other olfactory receptor families in crypt neurons. These results suggest that the vast majority of the crypt neuron population may select one and the same olfactory receptor gene, a "one cell type-one receptor" mode of expression. Such an expression pattern is familiar in the visual system, with rhodopsin as the sole light receptor of rod photoreceptor cells, but unexpected in the sense of smell.

  4. Tagging methods for estimating population size and mortality rates of inland striped bass populations

    Science.gov (United States)

    Hightower, Joseph E.; Pollock, Kenneth H.

    2013-01-01

    Striped bass Morone saxatilis in inland reservoirs play an important role ecologically and in supporting recreational fishing. To manage these populations, biologists need information about abundance and mortality. Abundance estimates can be used to assess the effectiveness of stocking programs that maintain most reservoir striped bass populations. Mortality estimates can indicate the relative impact of fishing versus natural mortality and the need for harvest regulation. The purpose of this chapter is to evaluate tagging studies as a way of obtaining information about abundance and mortality. These approaches can be grouped into three broad categories: tag recapture, tag return, and telemetry. Tag-recapture methods are typically used to estimate population size and other demographic parameters but are often difficult to apply in large systems. A fishing tournament can be an effective way of generating tagging or recapture effort in large systems, compared to using research sampling only. Tag-return methods that rely on angler harvest and catch and release can be used to estimate fishing (F) and natural (M) mortality rates and are a practical approach in large reservoirs. The key to success in tag-return studies is to build in auxiliary studies to estimate short-term tagging mortality, short- and longterm tag loss, reporting rate, and mortality associated with catch and release. F and M can also be estimated using telemetry tags. Advantages of this approach are that angler nonreporting does not bias estimates and fish with transmitters provide useful ecological data. Cost can be a disadvantage of telemetry studies; thus, combining telemetry tags with conventional tag returns in an integrated analysis is often the optimal approach. In summary, tagging methods can be a powerful tool for assessing the effectiveness of inland striped bass stocking programs and the relative impact of fishing versus natural mortality

  5. Extended Viral Shedding of a Low Pathogenic Avian Influenza Virus by Striped Skunks (Mephitis mephitis)

    Science.gov (United States)

    Root, J. Jeffrey; Shriner, Susan A.; Bentler, Kevin T.; Gidlewski, Thomas; Mooers, Nicole L.; Ellis, Jeremy W.; Spraker, Terry R.; VanDalen, Kaci K.; Sullivan, Heather J.; Franklin, Alan B.

    2014-01-01

    Background Striped skunks (Mephitis mephitis) are susceptible to infection with some influenza A viruses. However, the viral shedding capability of this peri-domestic mammal and its potential role in influenza A virus ecology are largely undetermined. Methodology/Principal Findings Striped skunks were experimentally infected with a low pathogenic (LP) H4N6 avian influenza virus (AIV) and monitored for 20 days post infection (DPI). All of the skunks exposed to H4N6 AIV shed large quantities of viral RNA, as detected by real-time RT-PCR and confirmed for live virus with virus isolation, from nasal washes and oral swabs (maximum ≤106.02 PCR EID50 equivalent/mL and ≤105.19 PCR EID50 equivalent/mL, respectively). Some evidence of potential fecal shedding was also noted. Following necropsy on 20 DPI, viral RNA was detected in the nasal turbinates of one individual. All treatment animals yielded evidence of a serological response by 20 DPI. Conclusions/Significance These results indicate that striped skunks have the potential to shed large quantities of viral RNA through the oral and nasal routes following exposure to a LP AIV. Considering the peri-domestic nature of these animals, along with the duration of shedding observed in this species, their presence on poultry and waterfowl operations could influence influenza A virus epidemiology. For example, this species could introduce a virus to a naive poultry flock or act as a trafficking mechanism of AIV to and from an infected poultry flock to naive flocks or wild bird populations. PMID:24489638

  6. Flexible registration method for light-stripe sensors considering sensor misalignments

    Science.gov (United States)

    Gorschenew, W.; Kaestner, M.; Reithmeier, Eduard

    2017-06-01

    In many application areas such as object reconstruction or quality assurance, it is required to completely or partly measure the shape of an object or at least the cross section of the required object region. For complex geometries, therefore, multiple views are needed to bypass undercuts respectively occlusions. Hence, a multi-sensor measuring system for complex geometries has to consist of multiple light-stripe sensors that are surrounding the measuring object in order to complete the measurements in a prescribed time. The number of sensors depends on the object geometry and dimensions. In order to create a uniform 3D data set from the data of individual sensors, a registration of each individual data set into a common global coordinate system has to be performed. Stateof- the-art registration methods for light-stripe sensors use only data from object intersection with the respective laser plane of each sensor. At the same time the assumption is met that all laser planes are coplanar and that there are corresponding points in two data sets. However, this assumption does not represent the real case, because it is nearly impossible to align multiple laser planes in the same plane. For this reason, sensor misalignments are neglected by this assumption. In this work a new registration method for light-stripe sensors is presented that considers sensor misalignments as well as intended sensor displacements and tiltings. The developed method combines 3D pose estimation and triangulated data to properly register the real sensor pose in 3D space.

  7. Salinity stress, enhancing basal and induced immune responses in striped catfish Pangasianodon hypophthalmus (Sauvage).

    Science.gov (United States)

    Schmitz, Mélodie; Ziv, Tamar; Admon, Arie; Baekelandt, Sébastien; Mandiki, Syaghalirwa N M; L'Hoir, Maëlenn; Kestemont, Patrick

    2017-09-07

    In the Mekong Delta, striped catfish are faced with chronic salinity stress related to saltwater intrusion induced by global climatic changes. In this study, striped catfish juveniles were submitted to a prolonged salinity stress (up to 10ppt) over three weeks followed by infection with a virulent bacterial strain, Edwardsiella ictaluri. Osmoregulatory parameters were investigated. In addition, a label free quantitative proteomics workflow was performed on kidneys. The workflow consisted of an initial global profiling of relative peptide abundances (by LC/MS, peak area quantification based on extracted ion currents), followed by identification (by MS/MS). The aim of the study was to highlight specific functional pathways modified during realistic salinity stress, particularly those involved in immunity. In kidney proteome, 2483 proteins were identified, of which 400 proteins were differentially expressed between the freshwater and the saline water conditions. Several pathways and functional categories were highlighted, mostly related to energy metabolism, protein metabolism, actin cytoskeleton, signaling, immunity, and detoxification. In particular, the responsiveness of proteins involved in small GTPases and Mitogen Activated Protein Kinase p38 signaling, phagolysosome maturation, and T-cells regulation is discussed. In the Mekong River Delta (Vietnam), striped catfish production is threatened by extensive sea water intrusion exacerbated by sea level rise. In fish, the effect of chronic exposure to salinity stress on immune capacities and response to disease has been poorly investigated. This study aims to highlight the main molecular changes occurring in the kidney during acclimation to salinity stress, particularly those involved in the immune defences of fish. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Optical sectioning microscopes with no moving parts using a micro-stripe array light emitting diode.

    Science.gov (United States)

    Poher, V; Zhang, H X; Kennedy, G T; Griffin, C; Oddos, S; Gu, E; Elson, D S; Girkin, M; French, P M W; Dawson, M D; Neil, M A

    2007-09-03

    We describe an optical sectioning microscopy system with no moving parts based on a micro-structured stripe-array light emitting diode (LED). By projecting arbitrary line or grid patterns onto the object, we are able to implement a variety of optical sectioning microscopy techniques such as grid-projection structured illumination and line scanning confocal microscopy, switching from one imaging technique to another without modifying the microscope setup. The micro-structured LED and driver are detailed and depth discrimination capabilities are measured and calculated.

  9. Primary diffuse malignant peritoneal mesothelioma in a striped skunk (Mephitis mephitis).

    Science.gov (United States)

    Kim, Su-Min; Oh, Yeonsu; Oh, Suk-Hun; Han, Jeong-Hee

    2016-03-01

    A 10-year-old female striped skunk (Mephitis mephitis) was admitted with severe abdominal distension and lethargy. Cytological examination of the peritoneal fluid revealed activated mesothelial cells. At necropsy, numerous growing together, projecting, 2 to 20 mm in diameter tawny to white masses were scattered throughout the peritoneum including the mesentery, omentum and intestinal serosa. Microscopically, the tumor was composed of prominent papillo-tubular structures, and immunohistochemically, the spindle to polygonal-shaped tumor cells with nuclear polymorphism were strongly reactive for calretinin. Based on those diagnostic features, the neoplasia was diagnosed as malignant mesothelioma. This is the first case report of mesothelioma in the skunk.

  10. Polymorphic microsatellite markers for the striped skunk, Mephitis mephitis, and other mephitids.

    Science.gov (United States)

    Dragoo, Jerry W; Coan, Kathryn E; Moore, Kristin A; Henke, Scott E; Fleischer, Robert C; Wisely, Samantha M

    2009-01-01

    We report 10 polymorphic microsatellite loci primers developed for striped skunks (Mephitis mephitis), a widespread mesocarnivore in North America. Numbers of alleles in these loci ranged from seven to 14 and the observed heterozygosity ranged from 0.76 to 1.0. These primers will be useful for studying population dynamics of skunks where rabies is endemic and will be useful to estimate genetic relatedness among females sharing winter dens. Most of these primers amplify across species within the Mephitidae. © 2008 The Authors. Journal compilation © 2008 Blackwell Publishing Ltd.

  11. Electronic structure of a striped nickelate studied by the exact exchange for correlated electrons (EECE) approach

    KAUST Repository

    Schwingenschlögl, Udo

    2009-12-01

    Motivated by a RIXS study of Wakimoto, et al.(Phys. Rev. Lett., 102 (2009) 157001) we use density functional theory to analyze the magnetic order in the nickelate La5/3Sr1/3NiO4 and the details of its crystal and electronic structure. We compare the generalized gradient approximation to the hybrid functional approach of exact exchange for correlated electrons (EECE). In contrast to the former, the latter reproduces the insulating state of the compound and the midgap states. The EECE approach, in general, appears to be appropriate for describing stripe phases in systems with orbital degrees of freedom. Copyright © EPLA, 2009.

  12. Stripe patterns in two-dimensional systems with core-corona molecular architecture.

    Science.gov (United States)

    Malescio, Gianpietro; Pellicane, Giuseppe

    2004-08-01

    The behavior of a two-dimensional system of particles interacting through a potential consisting of a hard core surrounded by a soft repulsive corona is investigated at several densities and temperatures. We find that the competition between hard and soft repulsions gives origin to the spontaneous formation of spatial patterns resembling stripe textures. The effect of varying the hard and soft core radii ratio as well as that of adding an attractive component to the interparticle interaction is studied. The model investigated is relevant for macromolecular topologies possessing two intrinsic length scales.

  13. The IAC Stripe 82 Legacy Project: a wide-area survey for faint surface brightness astronomy

    Science.gov (United States)

    Fliri, Jürgen; Trujillo, Ignacio

    2016-02-01

    We present new deep co-adds of data taken within Stripe 82 of the Sloan Digital Sky Survey (SDSS), especially stacked to reach the faintest surface brightness limits of this data set. Stripe 82 covers 275 ° ^2 within -50° ≤ RA ≤ +60° and -1.25° ≤ Dec. ≤ +1.25°. We discuss the steps of our reduction which puts special emphasis on preserving the characteristics of the background (sky + diffuse light) in the input images using a non-aggressive sky subtraction strategy. Our reduction reaches a limit of ˜28.5 mag arcsec-2 (3σ, 10 × 10 arcsec2) in the r band. The effective surface brightness limit (50 per cent completeness for exponential light distribution) lies at ˜ 25.5 mag arcsec-2. For point sources, we reach 50 per cent completeness limits (3σ level) of (24.2, 25.2, 24.7, 24.3, 23.0) mag in (u, g, r, I, z). This is between 1.7 and 2.0 mag deeper than the single-epoch SDSS releases. The co-adds show point spread functions (PSFs) with median full width at half-maximum values ranging from 1 arcsec in I and z to 1.3 arcsec in the u band. The imaging data are made publicly available at http://www.iac.es/proyecto/stripe82. The release includes deep co-adds and representations of the PSF for each field. Additionally, we provide object catalogues with stars and galaxies confidently separated until g ˜ 23 mag. The IAC Stripe 82 co-adds offer a rather unique possibility to study the low surface brightness Universe, exemplified by the discovery of stellar streams around NGC 0426 and NGC 0936. We also discuss further science cases like stellar haloes and disc truncations, low surface brightness galaxies, the intracluster light in galaxy clusters and the diffuse emission of Galactic dust known as Galactic Cirrus.

  14. Data base of dose coefficients called ecrin-V1-internet reference handbook

    International Nuclear Information System (INIS)

    Perrin, M.L.

    2003-07-01

    The objective of this data base is to dispose on a only computer medium the values of radiation doses allowing to guarantee the tracing and the coherence of radiation doses received by man. These data are usable to evaluate the risks in the frame of studies or expertise. They include the doses coming from external irradiations, internal contamination by inhalation or ingestion and receive by workers or public. The definitions and reference values come from international publications (the list is given). (N.C.)

  15. Ultra-wideband receiver

    Science.gov (United States)

    McEwan, Thomas E.

    1994-01-01

    An ultra-wideband (UWB) receiver utilizes a strobed input line with a sampler connected to an amplifier. In a differential configuration, .+-.UWB inputs are connected to separate antennas or to two halves of a dipole antenna. The two input lines include samplers which are commonly strobed by a gating pulse with a very low duty cycle. In a single ended configuration, only a single strobed input line and sampler is utilized. The samplers integrate, or average, up to 10,000 pulses to achieve high sensitivity and good rejection of uncorrelated signals.

  16. Stripe segregation and magnetic coupling in the nickelate La 5/3Sr1/3NiO4

    KAUST Repository

    Schwingenschlögl, Udo

    2009-03-02

    We investigate the consequences of the stripe formation in the nickelate La5/3Sr1/3NiO4 for the details of its crystal structure and electronic states. Our data are based on numerical simulations within density functional theory (DFT) and the generalized gradient approximation (GGA). The on-site Coulomb interaction is included in terms of the LDA+U scheme. Structure optimization of preliminary experimental data indicates a strong interaction between the structural and electronic degrees of freedom. In particular, we find a segregation of the diagonal filled stripes induced by a delicate interplay with the magnetic coupling. Beyond the cooperative effect of stripe segregation and spin order, distinct octahedral distortions are essential for the formation of an insulating state. © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Uptake, distribution, and depuration of 14C-benzene in northern anchovy, Engraulis mordax, and striped bass, Morone saxatilis

    International Nuclear Information System (INIS)

    Korn, S.; Hirsch, N.; Struhsaker, J.W.

    1976-01-01

    The uptake, distribution, and depuration of water-soluble, monocyclic hydrocarbon contained in petroleum and refined products was studied in two species of marine fish. Mature northern anchovy, Engraulis mordax, and juvenile striped bass, Morone saxatilis, were exposed to sublethal concentrations of O 14 -benzene for 48 h. Residues in tissues exhibiting a high lipid content or representing apparent major metabolic sites were measured during the exposure and afterwards when the fish were transferred to clean seawater. Fish exhibited a rapid uptake over a wide range of benzene concentrations in the water column. Accumulation in anchovy was considerably greater than in striped bass. Results indicate that the pathway of hydrocarbons through the liver, gallbladder, intestines, and colon is a major depuration route. Residues were depurated rapidly after cessation of exposure; in striped bass tissues most residues were undetectable by 7 days

  18. Study the effect of striping in two-step anodizing process on pore arrangement of nano-porous alumina

    International Nuclear Information System (INIS)

    Rahimi, M.H.; Saramad, S.; Tabaian, S.H.; Marashi, S.P.; Zolfaghari, A.; Mohammadalinezhad, M.

    2009-01-01

    Two-step anodic oxidation of aluminum is generally employed to produce the ordered porous anodized alumina (PAA). Dissolving away (striping) the oxide film after the first anodizing step plays a key role in the final arrangement of nano-pores. In this work, different striping durations between 1 and 6 h were applied to the sample that was initially anodized at a constant voltage of 40 V at 17 deg. C for 15 h. The striping duration of 3 h was realized as the optimum time for achieving the best ordering degree for the pores. Scanning electron microscopy (SEM) was used during and at the end of the process to examine the cross section and finishing surface of the specimens. Linear-angular fast Fourier transform (LA-FFT), an in-house technique based on MATLAB software, was employed to assess the ordering degree of the anodized samples.

  19. Mapping bound plasmon propagation on a nanoscale stripe waveguide using quantum dots: influence of spacer layer thickness

    Directory of Open Access Journals (Sweden)

    Chamanei S. Perera

    2015-10-01

    Full Text Available In this paper we image the highly confined long range plasmons of a nanoscale metal stripe waveguide using quantum emitters. Plasmons were excited using a highly focused 633 nm laser beam and a specially designed grating structure to provide stronger incoupling to the desired mode. A homogeneous thin layer of quantum dots was used to image the near field intensity of the propagating plasmons on the waveguide. We observed that the photoluminescence is quenched when the QD to metal surface distance is less than 10 nm. The optimised spacer layer thickness for the stripe waveguides was found to be around 20 nm. Authors believe that the findings of this paper prove beneficial for the development of plasmonic devices utilising stripe waveguides.

  20. Optical, mechanical and TEM assessment of titania-doped Bi2V1 ...

    Indian Academy of Sciences (India)

    aDepartment of Material Science and Engineering, Holden Hall, Virginia Tech, Blacksburg, Virginia 24060, USA. bSri Guru Granth Sahib World University, Fategarh Sahib 140 406, India. cSchool of Physics and Materials Science, Thapar University, Patiala 147 004, India. MS received 12 November 2013; revised 7 January ...

  1. Validity and Reliability of Adult ADHD Self-Report Scale Thai Version (ASRS-V1.1 TH).

    Science.gov (United States)

    Kiatrungrit, Komsan; Putthisri, Suwannee; Hongsanguansri, Sirichai; Wisajan, Pattaraporn; Jullagate, Sudawan

    2017-08-25

    The adult ADHD Self-Report Scale Thai version (ASRS-V1.1) (18 items) is a questionnaire for screening adult ADHD. To test the validity and reliability of the 18-question ASRS-V1.1 Thai version (ASRS-V1.1 TH) as a screening tool for adult ADHD. The original 18-question ASRS-V1.1 version was translated into Thai. The process was composed of forward-translation, synthesis of the translation, and back translation. Cross cultural adaptation, field testing, and final adjustment were completed consecutively. The 18-question ASRS-V1.1 TH were sent to 1,500 parents of kindergarten and elementary school students in Bangkok, Thailand. The diagnostic interview was randomly selected for 50 parents from the positive result group and 50 parents from the negative result group. The clinical interview for confirming diagnosis was run by 3 psychiatrists who were blinded to the results and used DSM-5 ADHD criteria for diagnosis. The 18-question ASRS-V1.1 TH had satisfactory internal consistency (Cronbach's alpha = 0.92: Cronbach's alpha = 0.87 for inattentive scale, Cronbach's alpha = 0.84 for hyperactive / impulsive scale). For testing the criteria validity, the questionnaire has an adequate. The AUC from the first 6 questions was 0.80 (95% CI: 0.68-0.92) while from the 18 questions was 0.71(95% CI: 0.55-0.86). The 18-question ASRS-V1.1TH is a psychometrically reliable and valid measure for screening adult ADHD in Thai clinical samples, especially the first 6 questions of the questionnaire.

  2. Linking retinotopic fMRI mapping and anatomical probability maps of human occipital areas V1 and V2.

    Science.gov (United States)

    Wohlschläger, A M; Specht, K; Lie, C; Mohlberg, H; Wohlschläger, A; Bente, K; Pietrzyk, U; Stöcker, T; Zilles, K; Amunts, K; Fink, G R

    2005-05-15

    Using functional MRI, we characterized field sign maps of the occipital cortex and created three-dimensional maps of these areas. By averaging the individual maps into group maps, probability maps of functionally defined V1 or V2 were determined and compared to anatomical probability maps of Brodmann areas BA17 and BA18 derived from cytoarchitectonic analysis (Amunts, K., Malikovic, A., Mohlberg, H., Schormann, T., Zilles, K., 2000. Brodmann's areas 17 and 18 brought into stereotaxic space-where and how variable? NeuroImage 11, 66-84). Comparison of areas BA17/V1 and BA18/V2 revealed good agreement of the anatomical and functional probability maps. Taking into account that our functional stimulation (due to constraints of the visual angle of stimulation achievable in the MR scanner) only identified parts of V1 and V2, for statistical evaluation of the spatial correlation of V1 and BA17, or V2 and BA18, respectively, the a priori measure kappa was calculated testing the hypothesis that a region can only be part of functionally defined V1 or V2 if it is also in anatomically defined BA17 or BA18, respectively. kappa = 1 means the hypothesis is fully true, kappa = 0 means functionally and anatomically defined visual areas are independent. When applying this measure to the probability maps, kappa was equal to 0.84 for both V1/BA17 and V2/BA18. The data thus show a good correspondence of functionally and anatomically derived segregations of early visual processing areas and serve as a basis for employing anatomical probability maps of V1 and V2 in group analyses to characterize functional activations of early visual processing areas.

  3. Selective silencing of Na(V)1.7 decreases excitability and conduction in vagal sensory neurons.

    Science.gov (United States)

    Muroi, Yukiko; Ru, Fei; Kollarik, Marian; Canning, Brendan J; Hughes, Stephen A; Walsh, Stacey; Sigg, Martin; Carr, Michael J; Undem, Bradley J

    2011-12-01

    There has been much information learned in recent years about voltage gated sodium channel (Na(V)) subtypes in somatosensory pain signalling, but much less is known about the role of specific sodium channel subtypes in the vagal sensory system. In this study, we developed a technique using adeno-associated viruses (AAVs) to directly introduce shRNA against Na(V)1.7 subtype gene into the vagal sensory ganglia of guinea pigs in vivo. Na(V)1.7 gene expression in nodose ganglia was effectively and selectively reduced without influencing the expression of other sodium channel subtype genes including Na(V)1.1, 1.2, 1.3 1.6, 1.8, or 1.9. Using a whole cell patch-clamp technique, this effect on Na(V)1.7 gene expression coincided with a reduction in tetrodotoxin-sensitive sodium current, a requirement for much larger depolarizing stimulus to initiate action potentials, and reduction in repetitive action potential discharge. Extracellular recordings in the isolated vagus nerve revealed that the conduction of action potentials in sensory A- and C-fibres in many neurons was effectively abolished after Na(V)1.7 shRNA introduction. Moreover, bilateral Na(V)1.7 shRNA injected animals survived for several months and the vagal reflex behaviour, exemplified by citric acid-induced coughing, was significantly suppressed. These data indicate that selectively silencing Na(V)1.7 ion channel expression leads to a substantial decrease in neural excitability and conduction block in vagal afferent nerves.

  4. Decomposition of BOLD Activity into Tuned and Untuned Components Reveals Cohabitation of Stimulus and Choice Information in V1

    Directory of Open Access Journals (Sweden)

    Kyoung Whan Choe

    2012-10-01

    Full Text Available Recent studies on V1 report top-down modulation of input-driven responses of sensory neurons, implying that exogenous sensory drives and endogenous top-down drives jointly determine V1 responses. By measuring fMRI responses in conjunction with a classification task on ambiguous ring stimuli, we sought to understand how V1 carries out its encoding operation on afferent currents while being adaptively modulated by top-down currents associated with perceptual tasks. Population activity of V1, as in its raw eccentricity profiles, failed to resolve the threshold differences between the ring stimuli due to large moment-to-moment fluctuations. The analysis of variance indicated that stimulus-evoked responses explain only one-fifth of the total variance and fMRI responses were highly correlated among eccentricity-bins, implying that a substantial fraction of V1 responses fluctuate as a whole. This led us to decompose the raw fMRI responses into untuned and tuned components: average response across eccentricity-bins and residual responses from the average, respectively, the former varying only in time and the latter varying in both space and time. The tuned responses revealed the veridical encoding operation of V1 by readily distinguishing between the ring stimuli, which was impossible with the raw fMRI responses. In contrast, the untuned were correlated with two major aspects of choice behavior—inter-trial variability in response time and inter-subject variability in response bias. We propose that this cohabitation of stimulus and choice information in V1 indicates the presence of top-down exertion of gain modulation on the early processing stage by the high-tier stage that accumulates evidence for perceptual choices.

  5. Identification and mapping of leaf, stem and stripe rust resistance quantitative trait loci and their interactions in durum wheat.

    Science.gov (United States)

    Singh, A; Pandey, M P; Singh, A K; Knox, R E; Ammar, K; Clarke, J M; Clarke, F R; Singh, R P; Pozniak, C J; Depauw, R M; McCallum, B D; Cuthbert, R D; Randhawa, H S; Fetch, T G

    2013-02-01

    Leaf rust (Puccinia triticina Eriks.), stripe rust (Puccinia striiformis f. tritici Eriks.) and stem rust (Puccinia graminis f. sp. tritici) cause major production losses in durum wheat (Triticum turgidum L. var. durum). The objective of this research was to identify and map leaf, stripe and stem rust resistance loci from the French cultivar Sachem and Canadian cultivar Strongfield. A doubled haploid population from Sachem/Strongfield and parents were phenotyped for seedling reaction to leaf rust races BBG/BN and BBG/BP and adult plant response was determined in three field rust nurseries near El Batan, Obregon and Toluca, Mexico. Stripe rust response was recorded in 2009 and 2011 nurseries near Toluca and near Njoro, Kenya in 2010. Response to stem rust was recorded in field nurseries near Njoro, Kenya, in 2010 and 2011. Sachem was resistant to leaf, stripe and stem rust. A major leaf rust quantitative trait locus (QTL) was identified on chromosome 7B at Xgwm146 in Sachem. In the same region on 7B, a stripe rust QTL was identified in Strongfield. Leaf and stripe rust QTL around DArT marker wPt3451 were identified on chromosome 1B. On chromosome 2B, a significant leaf rust QTL was detected conferred by Strongfield, and at the same QTL, a Yr gene derived from Sachem conferred resistance. Significant stem rust resistance QTL were detected on chromosome 4B. Consistent interactions among loci for resistance to each rust type across nurseries were detected, especially for leaf rust QTL on 7B. Sachem and Strongfield offer useful sources of rust resistance genes for durum rust breeding.

  6. Application of the MASH v1.0 Code System to radiological warfare radiation threats

    International Nuclear Information System (INIS)

    Johnson, J.O.; Santoro, R.T.; Smith, M.S.

    1994-01-01

    Nuclear hardening capabilities of US and foreign ground force systems is a primary concern of the Department of Defense (DoD) and US Army. The Monte Carlo Adjoint Shielding Code System -- MASH v1.0 was developed at Oak Ridge National Laboratory (ORNL) to analyze these capabilities, i.e. the shielding effectiveness, for prompt radiation from a nuclear weapon detonation. Rapidly changing world events and the proliferation of nuclear weapons related technology have increased the kinds of nuclear threats to include intentionally dispersed radiation sources and fallout from tactical nuclear weapons used in the modern AirLand battlefield scenario. Consequently, a DoD area of increasing interest focuses on determining the shielding effectiveness of foreign and US armored vehicles to radiological warfare and fallout radiation threats. To demonstrate the applicability of MASH for analyzing dispersed radiation source problems, calculations have been completed for two distributed sources; a dispersed radiation environment simulated by a uniformly distributed 60 Co source, and a 235 U fission weapon fallout source. Fluence and dose assessments were performed for the free-field, the inside of a steel-walled two-meter box, in a phantom standing in the free-field, and in a phantom standing in the two-meter box. The results indicate substantial radiation protection factors for the 60 Co dispersed radiation source and the fallout source compared to the prompt radiation protection factors. The dose protection factors ranged from 40 to 95 for the two-meter box and from 55 to 123 for the mid-gut position of the phantom standing in the box. The results further indicate that a 60 Co source might be a good first order approximation for a tactical fission weapon fallout protection factor analysis

  7. Commissioning tests at Bohunice NPP V1 unit 2 after reconstruction in 1998

    International Nuclear Information System (INIS)

    Pajtinka, A.; Tvaroska, V.; Wiening, K.-H.; Mueller, B.

    2000-01-01

    The last and the most extensive stage in the reconstruction project of the Bohunice NPP started in July 1998. The main activities performed during a 6-month scheduled unit 2 outage included: - Installation of a new emergency core cooling system with an increased capacity according to the defined broader break spectrum for LOCA; - Reconstruction of the existing confinement spray system and installation of a new confinement pressure suppression system; - Completion of upgrading measures to increase the reliability of emergency power supply systems (replacement of low voltage switchgear, installation of new cabling for all loads important to safety, installation of new motor-generators and rectifier sets); - Connection to the plant and commissioning of the new reactor protection system. Comprehensive tests and checks performed on completion of installation work on the modified mechanical, electrical and I and C systems were important reasons for the absence of major problems during restart of the unit after the several project implementation phases. Operating experience at unit 2 since its recommissioning in January 1999 has confirmed that the required safety standards have been met and that operational reliability has been substantially increased at the sometime. Periodic testing is being performed in accordance with the limits and conditions for safe operation of Bohunice NPP. To date all these tests were completed without significant problems. The functions implemented in the new technology met the test program criteria, which were approved with authority, in all essential areas. Through the close cooperation of the partners involved and through the combined efforts of the various engineering and operating disciplines, technical and scheduling problems could be immediately identified and quickly resolved. In general, these kinds of projects require optimum cooperation among the parties involved. Modernization of the NPP Bohunice V1 unit 2 has shown, that all

  8. Evaluation of rumble stripes on low-volume rural roads in Iowa--phase I : final report, July 2009, tech transfer summary.

    Science.gov (United States)

    2009-07-01

    Objectives : Determine if rumble stripes can be used as a strategy to combat roadway departures and reduce the number of run-off-road (ROR) crashes. : Install edge line rumble stripes along the lane edge at a narrow width to avoid intruding o...

  9. The dissection and SSR mapping of a high-temperature adult-plant stripe rust resistance gene in American spring wheat cultivar Alturas

    Science.gov (United States)

    Stripe rust is one of major diseases in wheat production worldwide. The best economic and efficient method is to utilize resistant varieties. Alturas has high-temperature adult-plant resistance. In order to determine stripe rust resistance characteristics, resistance gene combination and molecular m...

  10. Reducing dietary protein in pond production of hybrid striped bass (Morone chrysops x M. saxatilis): Effects on fish performance and water quality dynamics

    Science.gov (United States)

    In previous work, we demonstrated that diets containing 40% digestible protein (DP) (45% crude protein) and 18 %lipid supplemented with Met and Lys resulted in superior performance and nutrient retentions in hybrid striped bass compared to less energy-dense diets when rearing hybrid striped bass at ...

  11. Estudo histomorfológico do músculo pectoralis de frangos de corte acometidos com white striping

    OpenAIRE

    Tamara Zinn Ferreira

    2014-01-01

    A seleção de linhagens de frangos de corte com altas taxas de crescimento e aumento de rendimento muscular vem contribuindo para o surgimento de perdas significativas na indústria avícola em decorrência de modificações anatômicas. Dentre estas alterações, destaca-se uma miopatia que se caracteriza pelo aparecimento de graus de estrias esbranquiçadas no músculo Pectoralis major, as quais seguem a direção da fibra muscular, referida como white striping. A etiologia da white striping ainda é des...

  12. A novel fungal hyperparasite of Puccinia striiformis f. sp. tritici, the causal agent of wheat stripe rust.

    Directory of Open Access Journals (Sweden)

    Gangming Zhan

    Full Text Available Puccinia striiformis f. sp. tritici (Pst, the causal fungus of wheat stripe rust, was previously reported to be infected by Lecanicillium lecanii, Microdochium nivale and Typhula idahoensis. Here, we report a novel hyperparasite on Pst. This hyperparasitic fungus was identified as Cladosporium cladosporioides (Fresen. GA de Vries based on morphological characteristics observed by light and scanning electron microscopy together with molecular data. The hyperparasite reduced the production and viability of urediniospores and, therefore, could potentially be used for biological control of wheat stripe rust.

  13. Efficacy of sublingual vectorized recombinant Bet v 1a in a mouse model of birch pollen allergic asthma.

    Science.gov (United States)

    Tourdot, Sophie; Airouche, Sabi; Berjont, Nathalie; Moussu, Hélène; Betbeder, Didier; Nony, Emmanuel; Bordas-Le Floch, Véronique; Baron-Bodo, Véronique; Mascarell, Laurent; Moingeon, Philippe

    2013-05-28

    Second generation sublingual allergy vaccines based upon recombinant allergens combined with vector systems are being developed as an alternative to conventional allergen extracts. Herein, we evaluated the efficacy of a recombinant form of the major allergen Bet v 1a (rBet v 1a) formulated as a mucoadhesive particle in a preclinical model of birch pollen (BP) respiratory allergy. BALB/c mice were sensitized to BP extracts by intraperitoneal injections followed by aerosol exposures. Sensitized mice underwent sublingual immunotherapy (SLIT) twice a week for eight weeks with either a BP extract or rBet v 1a formulated in amylopectin-based microparticles (MPA). SLIT efficacy was assessed using whole body plethysmography, lung histology and cell counts in broncho-alveolar lavages (BAL) as read outs. BP and/or rBet v 1a-specific T cell and antibody responses were monitored in lung and serum, respectively. IgA levels were measured in saliva. Mice sensitized to BP exhibit chronic airway hyperresponsiveness (AHR), lung inflammation (documented by compliance and resistance measurements), eosinophil infiltrates in BAL, as well as Bet v 1-specific Th2 biased responses. Both SLIT with soluble rBet v 1a (50μg/dose) and BP extract (equivalent to 50μg rBet v 1 per dose) lead to a significant reduction in AHR, lung eosinophilia and Th2 responses. A sub-optimal dose of 5μg of rBet v 1a displays a similar level of efficacy with a significant decrease of Th2 responses when formulated with MPA microparticles. In addition, allergen vectorization with mucoadhesive particles allows a faster reduction in AHR in sensitized animals. We demonstrate in a murine model of chronic BP respiratory allergy the efficacy of SLIT with vectorized rBet v 1a. Thus, combining recombinant allergens with mucoadhesive vector systems paves the ground for improved second generation sublingual allergy vaccines. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. miR-143 inhibits intracellular salmonella growth by targeting ATP6V1A in macrophage cells in pig.

    Science.gov (United States)

    Huang, Tinghua; Huang, Xiali; Yao, Min

    2018-04-01

    Salmonella infects many vertebrate species, and animals such as pigs can be colonized with Salmonella and become established carriers. Analyzing the roles of microRNA in intracellular proliferation is important for understanding the process of Salmonella infection. The objective of this study is to verify the regulation effect of miR-143 on ATP6V1A and its functions in the intracellular growth of Salmonella. A new miR-143 binding site was discovered in the 3' UTR of ATP6V1A using a newly developed prediction tool. The binding site was confirmed by binding site deletion assay. Real-time PCR results indicated that ATP6V1A was predominantly expressed in bone-marrow-derived macrophages, and the expression of miR-143 in different tissues was negatively correlated with ATP6V1A. The Salmonella proliferation assay showed that the expression of miR-143 could inhibit intracellular Salmonella growth in macrophages by target ATP6V1A. The results strongly suggest that miR-143 plays important regulatory roles in the development of Salmonella infection in animals. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Ca(v)1.2 calcium channel is glutathionylated during oxidative stress in guinea pig and ischemic human heart.

    Science.gov (United States)

    Tang, Helen; Viola, Helena M; Filipovska, Aleksandra; Hool, Livia C

    2011-10-15

    Glutathionylation as a posttranslational modification of proteins is becoming increasingly recognized, but its role in many diseases has not been demonstrated. Oxidative stress and alterations in calcium homeostasis are associated with the development of cardiac hypertrophy. Because the cardiac L-type Ca(2+) channel can be persistently activated after exposure to H(2)O(2), the aim of this study was to determine whether alterations in channel function were associated with glutathionylation of the α(1C) subunit (Ca(v)1.2) channel protein. Immunoblot analysis indicated that Ca(v)1.2 protein is significantly glutathionylated after exposure to H(2)O(2) and glutathione in vitro and after ischemia-reperfusion injury. L-type Ca(2+) channel macroscopic current and intracellular calcium were significantly increased in myocytes after exposure to oxidized glutathione and reversed by glutaredoxin. The increase in current correlated with an increase in open probability of the channel assessed as changes in single-channel activity after exposing the human long N-terminal Ca(v)1.2 to H(2)O(2) or oxidized glutathione. We also demonstrate that the Ca(v)1.2 channel is significantly glutathionylated in ischemic human heart. We conclude that oxidative stress is associated with an increase in glutathionylation of the Ca(v)1.2 channel protein. We suggest that the associated constitutive activity contributes to the development of pathology in ischemic heart disease. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. Adult ADHD Self-Report Scale (ASRS-v1.1) symptom checklist in patients with substance use disorders.

    Science.gov (United States)

    Daigre Blanco, Constanza; Ramos-Quiroga, J A; Valero, S; Bosch, R; Roncero, C; Gonzalvo, B; Nogueira, M

    2009-01-01

    Diagnosing attention deficit/hyperactivity disorder (ADHD) in patients with substance use disorder (SUD) is a complicated process in which a screening tool may be useful. We analyzed the ASRS-v1.1 validity in patients with SUD, considering the addiction severity and co-morbidity with depressive disorders, antisocial and borderline personality. Eighty outpatients with SUD were evaluated with the following instruments: ASRS-v1.1, CAAD-II, EuropASI, SCID-I, SCID-II. A factor analysis was performed with Varimax rotation to determine the structure of the intercorrelations among the items. Accuracy of ASRS-v1.1 was also analyzed. The diagnostic interview CAADID used as a gold standard indicated that 20% (95% confidence interval [CI]: 11-29) meet the criteria for ADHD. The ASRSv1.1 factor structure is marked by two factors related to inattention and hyperactivity / impulsivity that account for 67.7% of the variance. ASRS-v1.1, with a 4 cut-off, showed an 87.5% sensitivity and 68.6% specificity. ASRS-v1.1 is a simple screening tool that is useful and has acceptable validity for the identification of ADHD among addicted patients.

  17. Trade-offs between reproduction and health in free-ranging African striped mice.

    Science.gov (United States)

    Schoepf, I; Pillay, N; Schradin, C

    2017-05-01

    Energy is limited and must be allocated among competing life-history traits. Reproduction is considered one of the most energetically demanding life-history stages. Therefore, the amount of energy an individual invests in reproduction might carry fitness costs through reduced energy allocation to other activities such as health maintenance. We investigated whether reproduction impacts health in the seasonally breeding African striped mouse (Rhabdomys pumilio). We measured health in individuals that reproduced (breeders) and individuals that did not reproduce (their adult offspring) and tested whether: (1) breeders' health before reproduction was similar to that of their offspring (representing a baseline); (2) breeders' health deteriorated after reproduction; (3) breeders' health after reproduction was worse than that of their offspring. We collected blood samples from 12 breeding females and 11 breeding males both at the onset and at the end of the breeding season and from 12 adult daughters and 11 adult sons that did not reproduce at the end of the breeding season. Health was assessed using serum biochemistry analysis with VetScan Abaxis. Breeders differed considerably in their health before and after reproduction, particularly in parameters associated with digestion (lower amylase in males), metabolism (lower albumin, alkaline phosphatase, creatinine and glucose), osmoregulation (lower potassium and phosphorous in females) and immunity (higher globulin and altered alanine aminotransferase). Our results suggest that with the onset of breeding striped mice shifted their energy allocation from maintaining health to reproduction, indicating that investment into reproduction carries significant health costs.

  18. Inhibitory Effect of Camptothecin against Rice Bacterial Brown Stripe Pathogen Acidovorax avenae subsp. avenae RS-2.

    Science.gov (United States)

    Dong, Qiaolin; Luo, Ju; Qiu, Wen; Cai, Li; Anjum, Syed Ishtiaq; Li, Bin; Hou, Mingsheng; Xie, Guanlin; Sun, Guochang

    2016-07-27

    Camptothecin (CPT) has anticancer, antiviral, and antifungal properties. However, there is a dearth of information about antibacterial activity of CPT. Therefore, in this study, we investigated the inhibitory effect of CPT on Acidovorax avenae subsp. avenae strain RS-2, the pathogen of rice bacterial brown stripe, by measuring cell growth, DNA damage, cell membrane integrity, the expression of secretion systems, and topoisomerase-related genes, as well as the secretion of effector protein Hcp. Results indicated that CPT solutions at 0.05, 0.25, and 0.50 mg/mL inhibited the growth of strain RS-2 in vitro, while the inhibitory efficiency increased with an increase in CPT concentration, pH, and incubation time. Furthermore, CPT treatment affected bacterial growth and replication by causing membrane damage, which was evidenced by transmission electron microscopic observation and live/dead cell staining. In addition, quantitative real-time PCR analysis indicated that CPT treatment caused differential expression of eight secretion system-related genes and one topoisomerase-related gene, while the up-regulated expression of hcp could be justified by the increased secretion of Hcp based on the ELISA test. Overall, this study indicated that CPT has the potential to control the bacterial brown stripe pathogen of rice.

  19. Inhibitory Effect of Camptothecin against Rice Bacterial Brown Stripe Pathogen Acidovorax avenae subsp. avenae RS-2

    Directory of Open Access Journals (Sweden)

    Qiaolin Dong

    2016-07-01

    Full Text Available Camptothecin (CPT has anticancer, antiviral, and antifungal properties. However, there is a dearth of information about antibacterial activity of CPT. Therefore, in this study, we investigated the inhibitory effect of CPT on Acidovorax avenae subsp. avenae strain RS-2, the pathogen of rice bacterial brown stripe, by measuring cell growth, DNA damage, cell membrane integrity, the expression of secretion systems, and topoisomerase-related genes, as well as the secretion of effector protein Hcp. Results indicated that CPT solutions at 0.05, 0.25, and 0.50 mg/mL inhibited the growth of strain RS-2 in vitro, while the inhibitory efficiency increased with an increase in CPT concentration, pH, and incubation time. Furthermore, CPT treatment affected bacterial growth and replication by causing membrane damage, which was evidenced by transmission electron microscopic observation and live/dead cell staining. In addition, quantitative real-time PCR analysis indicated that CPT treatment caused differential expression of eight secretion system-related genes and one topoisomerase-related gene, while the up-regulated expression of hcp could be justified by the increased secretion of Hcp based on the ELISA test. Overall, this study indicated that CPT has the potential to control the bacterial brown stripe pathogen of rice.

  20. Effects of the Presidente Rivera oil spill on young-of-year striped bass

    International Nuclear Information System (INIS)

    Weisberg, S.B.; Burton, W.H.; Herman, R.L.

    1990-01-01

    On 24, June 1989, approximately 300,000 gallons of No. 6 fuel oil was spilled from the tanker Presidente Rivera into the Delaware River. This paper reports that the spill occurred in the center of the striped bass nursery area, only six weeks after the prime spawning period. Toxic effects of the spill on young-of-year striped bass were investigated using in situ bioassay techniques. Seventy-five liter chambers, each containing 30 hatchery-reared fish, were moored at four locations within the spill zone and at one upstream references are. chemical analysis of the water was conducted on area. Chemical analysis of the water was conducted on Days 1, 4, and 13 of the experiment. Despite significant oil fouling on chambers, no dissolved aromatic hydrocarbons were detected in the water column. Acute mortality was not apparent, with greater than 90% survival at all stations after four days. After 13 days, survival at the station closest to the spill site was about 20% less than at the reference station

  1. Evolution and genetics of root hair stripes in the root epidermis.

    Science.gov (United States)

    Dolan, L; Costa, S

    2001-03-01

    Root hair pattern develops in a number of different ways in angiosperm. Cells in the epidermis of some species undergo asymmetric cell divisions to form a smaller daughter cell from which a hair grows, and a larger cell that forms a non-hair epidermal cell. In other species any cell in the epidermis can form a root hair. Hair cells are arranged in files along the Arabidopsis root, located in the gaps between underlying cortical cell files. Epidermal cells overlying a single cortical cell file develop as non-hair epidermal cells. Genetic analysis has identified a transcription factor cascade required for the formation of this pattern. WEREWOLF (WER) and GLABRA2 (GL2) are required for the formation of non-hair epidermal cells while CAPRICE (CPC) is required for hair cell development. Recent analyses of the pattern of epidermal cells among the angiosperms indicate that this striped pattern of cell organization evolved from non-striped ancestors independently in a number of diverse evolutionary lineages. The genetic basis for the evolution of epidermal pattern in angiosperms may now be examined.

  2. DE-STRIPING FOR TDICCD REMOTE SENSING IMAGE BASED ON STATISTICAL FEATURES OF HISTOGRAM

    Directory of Open Access Journals (Sweden)

    H.-T. Gao

    2016-06-01

    Full Text Available Aim to striping noise brought by non-uniform response of remote sensing TDI CCD, a novel de-striping method based on statistical features of image histogram is put forward. By analysing the distribution of histograms,the centroid of histogram is selected to be an eigenvalue representing uniformity of ground objects,histogrammic centroid of whole image and each pixels are calculated first,the differences between them are regard as rough correction coefficients, then in order to avoid the sensitivity caused by single parameter and considering the strong continuity and pertinence of ground objects between two adjacent pixels,correlation coefficient of the histograms is introduces to reflect the similarities between them,fine correction coefficient is obtained by searching around the rough correction coefficient,additionally,in view of the influence of bright cloud on histogram,an automatic cloud detection based on multi-feature including grey level,texture,fractal dimension and edge is used to pre-process image.Two 0-level panchromatic images of SJ-9A satellite with obvious strip noise are processed by proposed method to evaluate the performance, results show that the visual quality of images are improved because the strip noise is entirely removed,we quantitatively analyse the result by calculating the non-uniformity ,which has reached about 1% and is better than histogram matching method.

  3. The effect of environmental hypercapnia and size on nitrite toxicity in the striped catfish (Pangasianodon hypophthalmus)

    DEFF Research Database (Denmark)

    Hvas, Malthe; Damsgaard, Christian; Gam, Le Thi Hong

    2016-01-01

    Striped catfish (Pangasianodon hypophthalmus) are farmed intensively at high stocking densities in Vietnam where they are likely to encounter environmental hypercapnia as well as occasional high levels of aquatic nitrite. Nitrite competes with Cl- for uptake at the branchial HCO3-/Cl- exchanger, ...... the ambient concentration, while small fish did not. Small P. hypophthalmus instead had significantly higher plasma [nitrate], and haemoglobin concentrations, revealing greater capacity for detoxifying nitrite by oxidising it to nitrate.......Striped catfish (Pangasianodon hypophthalmus) are farmed intensively at high stocking densities in Vietnam where they are likely to encounter environmental hypercapnia as well as occasional high levels of aquatic nitrite. Nitrite competes with Cl- for uptake at the branchial HCO3-/Cl- exchanger...... to a reduced nitrite uptake. To assess the effect of hypercapnia on nitrite uptake, fish were cannulated in the dorsal aorta, allowing repeated blood sampling for measurements of haemoglobin derivatives, plasma ions and acid-base status during exposure to 0.9 mM nitrite alone and in combination with acute...

  4. STRIPING NOISE REMOVAL OF IMAGES ACQUIRED BY CBERS 2 CCD CAMERA SENSOR

    Directory of Open Access Journals (Sweden)

    E. Amraei

    2014-10-01

    Full Text Available CCD Camera is a multi-spectral sensor that is carried by CBERS 2 satellite. Imaging technique in this sensor is push broom. In images acquired by the CCD Camera, some vertical striping noise can be seen. This is due to the detectors mismatch, inter detector variability, improper calibration of detectors and low signal-to-noise ratio. These noises are more profound in images acquired from the homogeneous surfaces, which are processed at level 2. However, the existence of these noises render the interpretation of the data and extracting information from these images difficult. In this work, spatial moment matching method is proposed to modify these images. In this method, the statistical moments such as mean and standard deviation of columns in each band are used to balance the statistical specifications of the detector array to those of reference values. After the removal of the noise, some periodic diagonal stripes remain in the image where their removal by using the aforementioned method seems impossible. Therefore, to omit them, frequency domain Butterworth notch filter was applied. Finally to evaluate the results, the image statistical moments such as the mean and standard deviation were deployed. The study proves the effectiveness of the method in noise removal.

  5. Magnetostatic Green's functions for the description of spin waves in finite rectangular magnetic dots and stripes

    International Nuclear Information System (INIS)

    Guslienko, Konstantin Y.; Slavin, Andrei N.

    2011-01-01

    We present derivation of the magnetostatic Green's functions used in calculations of spin-wave spectra of finite-size non-ellipsoidal (rectangular) magnetic elements. The elements (dots) are assumed to be single domain particles having uniform static magnetization. We consider the case of flat dots, when the in-plane dot size is much larger than the dot height (film thickness), and assume the uniform distribution of the variable magnetization along the dot height. The limiting cases of magnetic waveguides with rectangular cross-section and thin magnetic stripes are also considered. The developed method of tensorial Green's functions is used to solve the Maxwell equations in the magnetostatic limit, and to represent the Landau-Lifshitz equation of motion for the magnetization of a magnetic element in a closed integro-differential form. - Highlights: → The Green's functions method is used to solve the magnetostatic equations. → Explicit Green's functions are written for thin magnetic dots and stripes. → Spin-wave frequencies for finite rectangular magnetic elements are calculated.

  6. Striped-tailed Yellow-finch nesting success in abandoned mining pits from central Brazilian cerrado

    Directory of Open Access Journals (Sweden)

    DT. Gressler

    Full Text Available Suitability of degraded areas as breeding habitats can be tested through assessment of nest predation rates. In this study we estimated nest success in relation to several potential predictors of nest survival in the Stripe-tailed Yellow-finch (Sicalis citrina breeding in abandoned mining pits at Brasília National Park. We monitored 73 nests during the 2007-breeding season. Predation was the main cause of nest failure (n = 48, 66%; while six nests were abandoned (8% and 19 nests produced young (26%. Mayfield’s daily survival rates and nest success were 0.94 and 23%, respectively. Our results from nest survival models on program MARK indicated that daily survival rates increase linearly towards the end of the breeding season and decrease as nests aged. None of the nest individual covariates we tested - nest height, nest size, nest substrate, and edge effect - were important predictors of nest survival; however, nests placed on the most common plant tended to have higher survival probabilities. Also, there was no observer effect on daily survival rates. Our study suggests that abandoned mining pits may be suitable alternative breeding habitats for Striped-tailed Yellow-finches since nest survival rates were similar to other studies in the central cerrado region.

  7. The striped skunk (Mephitis mephitis) is an intermediate host for Sarcocystis neurona.

    Science.gov (United States)

    Cheadle, M A; Yowell, C A; Sellon, D C; Hines, M; Ginn, P E; Marsh, A E; MacKay, R J; Dame, J B; Greiner, E C

    2001-06-01

    Striped skunks, initially negative for antibodies to Sarcocystis neurona, formed sarcocysts in skeletal muscles after inoculation with S. neurona sporocysts collected from a naturally infected Virginia opossum (Didelphis virginiana). Skunks developed antibodies to S. neurona by immunoblot and muscles containing sarcocysts were fed to laboratory-reared opossums which then shed sporulated Sarcocystis sporocysts in their faeces. Mean dimensions for sporocysts were 11.0 x 7.5 microm and each contained four sporozoites and a residuum. Sarcocysts from skunks and sporocysts from opossums fed infected skunk muscle were identified as S. neurona using PCR and DNA sequence analysis. A 2-month-old, S. neurona-naive pony foal was orally inoculated with 5 x 10(5) sporocysts. Commercial immunoblot for antibodies to S. neurona performed using CSF collected from the inoculated pony was low positive at 4 weeks p.i., positive at 6 weeks p.i., and strong positive at 8 weeks p.i. Gamma-interferon gene knockout mice inoculated with skunk/opossum derived sporocysts developed serum antibodies to S. neurona and clinical neurologic disease. Merozoites of S. neurona present in the lung, cerebrum, and cerebellum of mice were detected by immunohistochemistry using polyclonal antibodies to S. neurona. Based on the results of this study, the striped skunk is an intermediate host of S. neurona.

  8. Neutral and acidic milk oligosaccharides of the striped skunk (Mephitidae: Mephitis mephitis).

    Science.gov (United States)

    Taufik, Epi; Sekii, Nobuhiro; Senda, Akitsugu; Fukuda, Kenji; Saito, Tadao; Eisert, Regina; Oftedal, Olav T; Urashima, Tadasu

    2013-07-01

    The biological significance of the tremendous variation in proportions of oligosaccharides and lactose among mammalian milks is poorly understood. We investigated milk oligosaccharides of the striped skunk (Mephitis mephitis) and compared these results to other species of the clade Mustelida. Individual oligosaccharides were identified by proton nuclear magnetic resonance spectroscopy. In the striped skunk, six oligosaccharides were identified: isoglobotriose, 2'-fucosyllactose, A-tetrasaccharide, Galili pentasaccharide, 3'-sialyllactose and monosialyl monogalactosyl lacto-N-neohexaose. Four of these have been found in related Mustelida and the other two in more distantly related carnivorans. The neutral and acidic oligosaccharides derive from three core structures: lactose (Gal(β1-4)Glc), lacto-N-neotetraose (Gal(β1-4)GlcNAc(β1-3)Gal(β1-4)Glc) and lacto-N-neohexaose (Gal(β1-4)GlcNAc(β1-3)[Gal(β1-4)GlcNAc(β1-6)]Gal(β1-4)Glc). © 2013 Japanese Society of Animal Science.

  9. Emergent Ising degrees of freedom above a double-stripe magnetic ground state

    Science.gov (United States)

    Zhang, Guanghua; Flint, Rebecca

    2017-12-01

    Double-stripe magnetism [Q =(π /2 ,π /2 )] has been proposed as the magnetic ground state for both the iron-telluride and BaTi2Sb2O families of superconductors. Double-stripe order is captured within a J1-J2-J3 Heisenberg model in the regime J3≫J2≫J1 . Intriguingly, besides breaking spin-rotational symmetry, the ground-state manifold has three additional Ising degrees of freedom associated with bond ordering. Via their coupling to the lattice, they give rise to an orthorhombic distortion and to two nonuniform lattice distortions with wave vector (π ,π ) . Because the ground state is fourfold degenerate, modulo rotations in spin space, only two of these Ising bond order parameters are independent. Here, we introduce an effective field theory to treat all Ising order parameters, as well as magnetic order, and solve it within a large-N limit. All three transitions, corresponding to the condensations of two Ising bond order parameters and one magnetic order parameter are simultaneous and first order in three dimensions, but lower dimensionality, or equivalently weaker interlayer coupling, and weaker magnetoelastic coupling can split the three transitions, and in some cases allows for two separate Ising phase transitions above the magnetic one.

  10. Calibration of Binocular Vision Sensors Based on Unknown-Sized Elliptical Stripe Images

    Directory of Open Access Journals (Sweden)

    Zhen Liu

    2017-12-01

    Full Text Available Most of the existing calibration methods for binocular stereo vision sensor (BSVS depend on a high-accuracy target with feature points that are difficult and costly to manufacture and. In complex light conditions, optical filters are used for BSVS, but they affect imaging quality. Hence, the use of a high-accuracy target with certain-sized feature points for calibration is not feasible under such complex conditions. To solve these problems, a calibration method based on unknown-sized elliptical stripe images is proposed. With known intrinsic parameters, the proposed method adopts the elliptical stripes located on the parallel planes as a medium to calibrate BSVS online. In comparison with the common calibration methods, the proposed method avoids utilizing high-accuracy target with certain-sized feature points. Therefore, the proposed method is not only easy to implement but is a realistic method for the calibration of BSVS with optical filter. Changing the size of elliptical curves projected on the target solves the difficulty of applying the proposed method in different fields of view and distances. Simulative and physical experiments are conducted to validate the efficiency of the proposed method. When the field of view is approximately 400 mm × 300 mm, the proposed method can reach a calibration accuracy of 0.03 mm, which is comparable with that of Zhang’s method.

  11. Development of structural response diagram approach to evaluation of thermal stress caused by thermal striping

    Energy Technology Data Exchange (ETDEWEB)

    Kasahara, Naoto; Yacumpai, Apisara [Japan Nuclear Cycle Development Inst., Oarai, Ibaraki (Japan). Oarai Engineering Center; Takasho, Hideki

    1999-02-01

    At incomplete mixing area of high temperature and low temperature fluids near the surface of structures, temperature fluctuation of fluid gives thermal fatigue damage to wall structures. This thermohydraulic and thermomechanical coupled phenomenon is called thermal striping, which has so complex mechanism and sometimes causes crack initiation on the structural surfaces that rational evaluation methods are required for screening rules in design codes. In this study, frequency response characteristics of structures and its mechanism were investigated by both numerical and theoretical methods. Based on above investigation, a structural response diagram was derived, which can predict stress amplitude of structures from temperature amplitude and frequency of fluids. Furthermore, this diagram was generalized to be the Non-dimensional structural response diagram by introducing non-dimensional parameters such as Biot number, non-dimensional frequency, and non-dimensional stress. The use of the Non-dimensional structural response diagram appears to evaluate thermal stress caused by thermal striping, rapidly without structural analysis, and rationally with considering attenuation by non-stationary heat transfer and thermal unloading. This diagram can also give such useful information as sensitive frequency range to adjust coupled thermohydraulic and thermomechanical analysis models taking account of four kinds of attenuation factors: turbulent mixing, molecular diffusion, non-stationary heat transfer, and thermal unloading. (author)

  12. Stem and stripe rust resistance in wheat induced by gamma rays and thermal neutrons

    International Nuclear Information System (INIS)

    Skorda, E.A.

    1977-01-01

    Attempts were made to produce rust-resistant mutants in wheat cultivars. Seeds of G-38290 and G-58383 (T. aestivum), Methoni and Ilectra (T. durum) varieties were irradiated with different doses of γ-rays (3.5, 5, 8, 11, 15 and 21 krad) and thermal neutrons (1.7, 4, 5.5, 7.5, 10.5 and 12.5x10 12 ) and the M 1 plants were grown under isolation in the field. The objective was mainly to induce stripe, leaf and stem rust resistance in G-38290, Methoni and Ilectra varieties and leaf rust resistance in G-58383. Mutations for rust resistance were detected by using the ''chimera method'' under natural and artificial field epiphytotic conditions in M 2 and successive generations. The mutants detected were tested for resistance to a broad spectrum of available races. Mutants resistant or moderately resistant to stripe and stem rusts but not to leaf rust, were selected from G-38290. From the other three varieties tested no rust-resistant mutants were detected. The frequency of resistant mutants obtained increased with increased γ-ray dose-rate, but not with increased thermal neutron doses. Some mutants proved to be resistant or moderately resistant to both rusts and others to one of them. Twenty of these mutants were evaluated for yield from M 5 to M 8 . Some of them have reached the final stage of regional yield trials and one, induced by thermal neutrons, was released this year. (author)

  13. Implications of power plant mortality for management of the Hudson River striped bass fishery

    International Nuclear Information System (INIS)

    Goodyear, C.P.

    1988-01-01

    The Atlantic coastal stock of striped bass apparently declined from colonial times to the early 1930s and subsequently recovered. The reasons for the decline and recovery are not known, but fishing remains a possible explanation, which would suggest population sensitivity to increased mortality. Evidence suggests that fishing mortality has been increasing in recent years and will continue to increase in the absence of management intervention. The consequence of increased fishing mortality is an increase in the marginal effect of the power plant mortality which based on the utilities' models and parameter fits, could result in important reductions in the Hudson River striped bass population. Any management actions imposed to arrest population decline or to increase yield per effort in the fishery would be required to mitigate the impact of the power plants by reducing fishing mortality. It is estimated that a 20% conditional power plant mortality is equivalent to a 14% increase in the number of average fishermen using the stock. Consequently, should any management intervention be required on behalf of the population, managers would be required to reduce fishing mortality by about 14% just to account for the power plant mortality. 26 refs., 5 figs., 4 tabs

  14. Visualization analysis of tiger-striped flow mark generation phenomena in injection molding

    Science.gov (United States)

    Owada, Shigeru; Yokoi, Hidetoshi

    2016-03-01

    The generation mechanism of tiger-striped flow marks of polypropylene (PP)/rubber/talc blends in injection molding was investigated by dynamic visualization analysis in a glass-inserted mold. The analysis revealed that the behavior of the melt flow front correlates with the flow mark generation. The cloudy part in the tiger-striped flow marks corresponded to the low transcription rate area of the melt diverging near the cavity wall, while the glossy part corresponded to the high transcription rate area of the melt converging toward the cavity wall side. The melt temperature at the high transcription rate area was slightly lower than that at the low transcription rate area. These phenomena resulted due to the difference in the temperature of the melt front that was caused by the asymmetric fountain flow. These results suggest the followings; At the moment when the melt is broken near the one side of cavity wall due to piling the extensional strains up to a certain level, the melt spurts out near the broken side. It results in generating asymmetric fountain flow temporarily to relax the extensional front surface, which moves toward the opposite side to form the high transcription area.

  15. Nanoscale stripe arrays templated on Moiré patterns in graphite

    Science.gov (United States)

    McNally, Michael J.; Koç, Mumin Mehmet; Torricelli, Gauthier; von Haeften, Klaus

    2016-04-01

    Large areas of nanoscale stripe arrays were produced by drop casting silica nanoparticle solutions on highly oriented pyrolytic graphite surfaces at room temperature and imaged with atomic force microscopy. The alignment of the striped areas always reflected the threefold symmetry of the graphite surface. Two different patterns were observed, with different coverages, line separations and mutual orientation, being offset by 30°. Measurement of the relative angles and separations of the line patterns showed a very good match with an underlying Moiré pattern, resulting from the rotation of the top graphene layers. Closer-spaced lines were attributed to the zig-zag direction of the Moiré pattern whereas wider-spaced lines belonged to the armchair direction. The different abundance and apparent difference in long-term stability suggested that stability was governed by the number of reactive vertices per unit area as opposed to the number of vertices per line-length. Whilst sequential images recorded over several days revealed long term stability of all zig-zag arrays, attachment and detachment of single nanoparticles was observed. By contrast, arrays aligned in the armchair direction appeared and vanished collectively, suggesting condensation and evaporation of a fluid of nanoparticles floating on the surface.

  16. Solar thermal energy receiver

    Science.gov (United States)

    Baker, Karl W. (Inventor); Dustin, Miles O. (Inventor)

    1992-01-01

    A plurality of heat pipes in a shell receive concentrated solar energy and transfer the energy to a heat activated system. To provide for even distribution of the energy despite uneven impingement of solar energy on the heat pipes, absence of solar energy at times, or failure of one or more of the heat pipes, energy storage means are disposed on the heat pipes which extend through a heat pipe thermal coupling means into the heat activated device. To enhance energy transfer to the heat activated device, the heat pipe coupling cavity means may be provided with extensions into the device. For use with a Stirling engine having passages for working gas, heat transfer members may be positioned to contact the gas and the heat pipes. The shell may be divided into sections by transverse walls. To prevent cavity working fluid from collecting in the extensions, a porous body is positioned in the cavity.

  17. Population activity statistics dissect subthreshold and spiking variability in V1.

    Science.gov (United States)

    Bányai, Mihály; Koman, Zsombor; Orbán, Gergő

    2017-07-01

    Response variability, as measured by fluctuating responses upon repeated performance of trials, is a major component of neural responses, and its characterization is key to interpret high dimensional population recordings. Response variability and covariability display predictable changes upon changes in stimulus and cognitive or behavioral state, providing an opportunity to test the predictive power of models of neural variability. Still, there is little agreement on which model to use as a building block for population-level analyses, and models of variability are often treated as a subject of choice. We investigate two competing models, the doubly stochastic Poisson (DSP) model assuming stochasticity at spike generation, and the rectified Gaussian (RG) model tracing variability back to membrane potential variance, to analyze stimulus-dependent modulation of both single-neuron and pairwise response statistics. Using a pair of model neurons, we demonstrate that the two models predict similar single-cell statistics. However, DSP and RG models have contradicting predictions on the joint statistics of spiking responses. To test the models against data, we build a population model to simulate stimulus change-related modulations in pairwise response statistics. We use single-unit data from the primary visual cortex (V1) of monkeys to show that while model predictions for variance are qualitatively similar to experimental data, only the RG model's predictions are compatible with joint statistics. These results suggest that models using Poisson-like variability might fail to capture important properties of response statistics. We argue that membrane potential-level modeling of stochasticity provides an efficient strategy to model correlations. NEW & NOTEWORTHY Neural variability and covariability are puzzling aspects of cortical computations. For efficient decoding and prediction, models of information encoding in neural populations hinge on an appropriate model of

  18. Astronomical component estimation (ACE v.1) by time-variant sinusoidal modeling

    Science.gov (United States)

    Sinnesael, Matthias; Zivanovic, Miroslav; De Vleeschouwer, David; Claeys, Philippe; Schoukens, Johan

    2016-09-01

    Accurately deciphering periodic variations in paleoclimate proxy signals is essential for cyclostratigraphy. Classical spectral analysis often relies on methods based on (fast) Fourier transformation. This technique has no unique solution separating variations in amplitude and frequency. This characteristic can make it difficult to correctly interpret a proxy's power spectrum or to accurately evaluate simultaneous changes in amplitude and frequency in evolutionary analyses. This drawback is circumvented by using a polynomial approach to estimate instantaneous amplitude and frequency in orbital components. This approach was proven useful to characterize audio signals (music and speech), which are non-stationary in nature. Paleoclimate proxy signals and audio signals share similar dynamics; the only difference is the frequency relationship between the different components. A harmonic-frequency relationship exists in audio signals, whereas this relation is non-harmonic in paleoclimate signals. However, this difference is irrelevant for the problem of separating simultaneous changes in amplitude and frequency. Using an approach with overlapping analysis frames, the model (Astronomical Component Estimation, version 1: ACE v.1) captures time variations of an orbital component by modulating a stationary sinusoid centered at its mean frequency, with a single polynomial. Hence, the parameters that determine the model are the mean frequency of the orbital component and the polynomial coefficients. The first parameter depends on geologic interpretations, whereas the latter are estimated by means of linear least-squares. As output, the model provides the orbital component waveform, either in the depth or time domain. Uncertainty analyses of the model estimates are performed using Monte Carlo simulations. Furthermore, it allows for a unique decomposition of the signal into its instantaneous amplitude and frequency. Frequency modulation patterns reconstruct changes in

  19. Performance of the Adult ADHD Self-Report Scale-v1.1 in Adults with Major Depressive Disorder

    Directory of Open Access Journals (Sweden)

    Boadie W. Dunlop

    2018-03-01

    Full Text Available Attention deficit/hyperactivity disorder (ADHD is an under-recognized comorbid disorder among patients with mood disorders. ADHD is an independent risk factor for suicidal ideation and behavior and contributes to many aspects of impaired function in adults. Diagnosis of ADHD in Major Depressive Disorder (MDD patients is challenging due to the overlap in cognitive symptoms between the two disorders. The ADHD Self-Report Scale, version 1.1 (ASRS-v1.1 is a widely used screening instrument for ADHD in adults but its accuracy has not been evaluated previously in treatment-seeking MDD patients. We administered the ASRS-v1.1 to 55 healthy controls and 40 adults with a primary psychiatric diagnosis of MDD who were participating in clinical research studies. ADHD diagnosis was assessed via structured interview with the adult ADHD module of the Mini International Neuropsychiatric Interview Plus version 6.0.0 (MINI along with a psychiatrist’s assessment. Overall, full-syndrome ADHD was diagnosed in 12.5% of the MDD patients. MDD patients endorsed all 18 items of the ASRS-v1.1 more frequently than the healthy controls and the number of ASRS-v1.1 items endorsed correlated with levels of anxiety in the MDD patients. The ASRS-v1.1 demonstrated fair performance for identifying full syndrome DSM-IV ADHD diagnosis, with sensitivity 60%, specificity: 68.6%, positive predictive value 21.4%, negative predictive value 92.3% and total classification accuracy of 67.5%. Positive predictive value improved substantially when the ADHD criterion requiring symptom onset before age 7 was omitted. In adult MDD patients, a negative ASRS-v1.1 screen strongly suggests the absence of ADHD but positive screen results require careful evaluation to determine whether self-reported ADHD symptoms simply emerge from depression or whether comorbid ADHD is present.

  20. NaV1.9 Potentiates Oxidized Phospholipid-Induced TRP Responses Only under Inflammatory Conditions

    Directory of Open Access Journals (Sweden)

    Corinna Martin

    2018-01-01

    Full Text Available Oxidized phospholipids (OxPL like oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (OxPAPC were recently identified as novel proalgesic targets in acute and chronic inflammatory pain. These endogenous chemical irritants are generated in inflamed tissue and mediate their pain-inducing function by activating the transient receptor potential channels TRPA1 and TRPV1 expressed in sensory neurons. Notably, prototypical therapeutics interfering with OxPL were shown to inhibit TRP channel activation and pain behavior. Here, we asked how OxPL excite primary sensory neurons of dorsal root ganglia (DRG neurons from mice of either sex. Acute stimulation of sensory neurons with the prototypical OxPL 1-palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine (PGPC evoked repetitive calcium spikes in small-diameter neurons. As NaV1.9, a voltage-gated sodium channel involved in nociceptor excitability, was previously shown to be essential for the generation of calcium spikes in motoneurons, we asked if this channel is also important for OxPL mediated calcium spike and action potential generation in nociceptors. In wild-type and NaV1.9-deficient neurons, the action potential firing rate and the calcium spike frequency to an acute PGPC stimulus was similar. When preincubated with inflammatory mediators, both, the action potential firing rate and the calcium spike frequency were markedly increased in response to an acute PGPC stimulus. However, this potentiating effect was completely lost in NaV1.9-deficient small-diameter neurons. After treatment with inflammatory mediators, the resting membrane potential of NaV1.9 KO neurons was slightly more negative than that of wild-type control neurons. This suggests that NaV1.9 channels are active under this condition and therefore increases the ease with which action potentials are elicited after OxPL stimulation. In summary, our data suggest that NaV1.9 has a switch function to potentiate the receptor potentials

  1. Persistent modification of Na{sub v}1.9 following chronic exposure to insecticides and pyridostigmine bromide

    Energy Technology Data Exchange (ETDEWEB)

    Nutter, Thomas J., E-mail: tnutter@dental.ufl.edu; Cooper, Brian Y., E-mail: bcooper@dental.ufl.edu

    2014-06-15

    Many veterans of the 1991 Gulf War (GW) returned from that conflict with a widespread chronic pain affecting deep tissues. Recently, we have shown that a 60 day exposure to the insecticides permethrin, chlorpyrifos, and pyridostigmine bromide (NTPB) had little influence on nociceptor action potential forming Na{sub v}1.8, but increased K{sub v}7 mediated inhibitory currents 8 weeks after treatment. Using the same exposure regimen, we used whole cell patch methods to examine whether the influences of NTPB could be observed on Na{sub v}1.9 expressed in muscle and vascular nociceptors. During a 60 day exposure to NTPB, rats exhibited lowered muscle pain thresholds and increased rest periods, but these measures subsequently returned to normal levels. Eight and 12 weeks after treatments ceased, DRG neurons were excised from the sensory ganglia. Whole cell patch studies revealed little change in voltage dependent activation and deactivation of Na{sub v}1.9, but significant increases in the amplitude of Na{sub v}1.9 were observed 8 weeks after exposure. Cellular studies, at the 8 week delay, revealed that NTPB also significantly prolonged action potential duration and afterhyperpolarization (22 °C). Acute application of permethrin (10 μM) also increased the amplitude of Na{sub v}1.9 in skin, muscle and vascular nociceptors. In conclusion, chronic exposure to Gulf War agents produced long term changes in the amplitude of Na{sub v}1.9 expressed in muscle and vascular nociceptors. The reported increases in K{sub v}7 amplitude may have been an adaptive response to increased Na{sub v}1.9, and effectively suppressed behavioral pain measures in the post treatment period. Factors that alter the balance between Na{sub v}1.9 and K{sub v}7 could release spontaneous discharge and produce chronic deep tissue pain. - Highlights: • Rats were treated 60 days with permethrin, chlorpyrifos and pyridostigmine bromide. • 8 weeks after treatments, Nav1.9 activation and deactivation were

  2. CERN apprentice receives award

    CERN Multimedia

    2008-01-01

    Another CERN apprentice has received an award for the quality of his work. Stéphane Küng (centre), at the UIG ceremony last November, presided over by Geneva State Councillor Pierre-François Unger, Head of the Department of Economics and Health. Electronics technician Stéphane Küng was honoured in November by the Social Foundation of the Union Industrielle Genevoise (UIG) as one of Geneva’s eight best apprentices in the field of mechatronics. The 20-year-old Genevan obtained his Federal apprentice’s certificate (Certificat fédéral de capacité - CFC) in June 2007, achieving excellent marks in his written tests at the Centre d’Enseignement Professionnel Technique et Artisanal (CEPTA). Like more than 200 youngsters before him, Stéphane Küng spent part of his four-year sandwich course working at CERN, where he followed many practical training courses and gained valuable hands-on experience in various technical groups and labs. "It’ always very gr...

  3. Arabidopsis thaliana Yellow Stripe1-Like4 and Yellow Stripe1-Like6 localize to internal cellular membranes and are involved in metal ion homeostasis.

    Directory of Open Access Journals (Sweden)

    Heng-Hsuan eChu

    2013-07-01

    Full Text Available Several members of the Yellow Stripe1-Like (YSL family of transporter proteins are able to transport metal-nicotianamine (NA complexes. Substantial progress has been made in understanding the roles of the Arabidopsis YSLs that are most closely related to the founding member of the family, ZmYS1 (e.g., AtYSL1, AtYSL2 and AtYSL3, but there is little information concerning members of the other two well-conserved YSL clades. Here, we provide evidence that AtYSL4 and AtYSL6, which are the only genes in Arabidopsis belong to YSL Group II, are localized to vacuole membranes and to internal membranes resembling endoplasmic reticulum. Both single and double mutants for YSL4 and YSL6 were rigorously analyzed, and have surprisingly mild phenotypes, in spite of the strong and wide-ranging expression of YSL6. However, in the presence of toxic levels of Mn and Ni, plants with mutations in YSL4 and YSL6 and plants overexpressing GFP-tagged YSL6 showed growth defects, indicating a role for these transporters in heavy metal stress responses.

  4. Two novel types of O-glycans on the mugwort pollen allergen Art v 1 and their role in antibody binding

    NARCIS (Netherlands)

    Leonard, Renaud; Petersen, Bent O.; Himly, Martin; Kaar, Waltraud; Wopfner, Nicole; Kolarich, Daniel; van Ree, Ronald; Ebner, Christof; Duus, Jens Ø; Ferreira, Fátima; Altmann, Friedrich

    2005-01-01

    Art v 1, the major allergen of mugwort (Artemisia vulgaris) pollen contains galactose and arabinose. As the sera of some allergic patients react with natural but not with recombinant Art v 1 produced in bacteria, the glycosylation of Art v 1 may play a role in IgE binding and human allergic

  5. 75 FR 13720 - Endangered and Threatened Wildlife and Plants; 90-Day Finding on a Petition to List the Striped...

    Science.gov (United States)

    2010-03-23

    ... extinction of the striped newt population. In summary, we find that the information provided in the petition... Provided in the Petition The petitioners state that although many amphibians are declining worldwide due to... potential population extinction. In summary, we find that the information provided in the petition, as well...

  6. Dynamics of longitudinal and transverse modes along the junction plane in GaAlAs stripe lasers

    DEFF Research Database (Denmark)

    Mengel, F; Ostoich, V

    1977-01-01

    Observations of the transient excitation of higher order transverse modes along the junction plane in DH GaAlAs stripe lasers during subnanosecond pulse modulation is reported. These modes are strongly excited at the onset of the light pulse, they decay during 200 ps, and reappear after 400-600 ps...

  7. Effect of ingredient particle sizes and dietary viscosity on digestion and faecal waste of striped catfish (Pangasianodon hypophthalmus)

    NARCIS (Netherlands)

    Tran, Tu; Hien, T.T.T.; Bosma, R.H.; Heinsbroek, L.T.N.; Verreth, J.A.J.; Schrama, J.W.

    2017-01-01

    The ingredients' particle size and dietary viscosity may alter digestion, performance and faecal waste management of fish. This study aimed to assess the effect of grinding screen sizes of feed ingredients and dietary viscosity on digestibility, faecal waste and performance of striped catfish

  8. Sloan Digital Sky Survey Standard Star Catalog for Stripe 82: The Dawn of Industrial 1% Optical Photometry

    National Research Council Canada - National Science Library

    Ivezic, Zeljko; Smith, J. A; Miknaitis, Gajus; Lin, Huan; Tucker, Douglas; Lupton, Robert H; Gunn, James E; Knapp, Gillian R; Strauss, Michael A; Sesar, Branimir

    2007-01-01

    ... (at least four per band, with a median of 10) in the ugriz system. The catalog includes 1.01 million nonvariable unresolved objects from the equatorial stripe 82 in the right ascension range and with the corresponding r-band...

  9. A record of Striped Hog-nosed Skunk Conepatus semistriatus in central Panama, between two known sub-ranges

    NARCIS (Netherlands)

    Esser, H.J.; Liefting, Y.; Kays, R.; Jansen, P.A.

    2012-01-01

    Striped Hog-nosed Skunk Conepatus semistriatus was camera-trapped in central Panama. The photographs, taken in a densely forested area, probably belong to a single, wandering, individual. These photographs represent the easternmost record of C. semistriatus in Central America and confirm an earlier,

  10. Differences in the response of a striped dolphin (Stenella coeruleoalba) and a harbour porpoise (Phocoena phocoena) to an acoustic alarm

    NARCIS (Netherlands)

    Kastelein, R.A.; Jennings, N.; Verboom, W.C.; Haan, D.de; Schooneman, N.M.

    2006-01-01

    Small cetacean bycatch in gillnet fisheries may be reduced by deterring odontocetes from nets acoustically. However, different odontocete species may respond differently to acoustic signals from alarms. Therefore, in this study a striped dolphin and a harbour porpoise were subjected simultaneously

  11. Differences in the response of a striped dolphin (Stenella coeruleoalba) and a harbour popoise (Phocoena phocoena) to an acoustic alarm

    NARCIS (Netherlands)

    Kastelein, R.A.; Jennings, N.; Verboom, W.C.; Haan, de D.; Schooneman, N.M.

    2006-01-01

    Small cetacean bycatch in gillnet fisheries may be reduced by deterring odontocetes from nets acoustically. However, different odontocete species may respond differently to acoustic signals from alarms. Therefore, in this study a striped dolphin and a harbour porpoise were subjected simultaneously

  12. Computer simulation model for the striped bass young-of-the-year population in the Hudson River

    International Nuclear Information System (INIS)

    Eraslan, A.H.; Van Winkle, W.; Sharp, R.D.; Christensen, S.W.; Goodyear, C.P.; Rush, R.M.; Fulkerson, W.

    1975-09-01

    This report presents a daily transient (tidal-averaged), longitudinally one-dimensional (cross-section-averaged) computer simulation model for the assessment of the entrainment and impingement impacts of power plant operations on young-of-the-year populations of the striped bass, Morone saxatilis, in the Hudson River

  13. Interactions with the actin cytoskeleton are required for cell wall localization of barley stripe mosaic virus TGB proteins

    Science.gov (United States)

    The host cytoskeleton and membrane system are the main routes by which plant viruses move within or between cells. Barley stripe mosaic virus (BSMV) -induced actin filament thickening was visualized in the cytoskeleton of agroinfiltrated Nicotiana benthamiana epidermal cells expressing DsRed:Talin. ...

  14. [Vibrational and rotational excitation of CO2 in the collisional quenching of H2(v = 1)].

    Science.gov (United States)

    Zhang, Wen-jun; Feng, Li; Li, Jia-ling; Liu, Jing; Dai, Kang; Shen, Yi-fan

    2014-06-01

    Energy transfer in H2 (1,1) +CO2 collisions was investigated using high resolution transient laser spectroscopy. Rotational state selective excitation of v = 1 for rotational level J = 1 was achieved by stimulated Raman pumping. Energy gain into CO2 resulting from collisions with H2 (1,1) was probed using transient absorption techniques, Distributions of nascent CO2 rotational populations in both the ground (00 degrees 0) state and the vibrationally excited (00 degrees 1) state were determined from overtone absorption measurements. Translational energy distributions of the recoiling CO2 in individual rovibrational states were determined through measurement of Doppler-broadened transient line shapes. A kinetic model was developed to describe rates for appearance of CO2 states resulting from collisions with H2(1,1). From scanned CARS (coherent anti-stokes Raman scattering) the spectral peaks population ratio n0/n1 was obtained, where n0 and n1 represent the number densities of H2 at the levels (0,1) and (1,1), respectively. Using rotational Boltzmann distribution of H2 (v = 0) at 300 K, n1 was yielded. Values for rate coefficients were obtained using data for CO2 (00 degrees 0) J = 48 to 76 and CO2 (00 degrees 1) J = 5 to 33. The rate coefficients derived from appearance of the (00 degrees 0) state have values of K(tr) = (3.9 ± 0.8) x 10(-11) cm3 x molecule(-1) x s(-1) for J = 48 and k(tr) = (1.4 ± 0.3) x 10(-10) cm3 x molecule(-1) x s(-1) for J = 76, with a monotonic increase for the higher J states. For the (00 degrees 1) state, values of k(tr) remain fairly constant at k(tr) = (4.3 ± 0.9) x 10(-12) cm3 x molecule(-1) x s(-1). Rotational populations for the nascent CO2 states were measured at 0. 5 μs following excitation of H2. The transient population for each state was fit using a Boltzmann rotational distribution. The CO2 (00 degrees 0) J = 48-76 rotational states were populated substantially relative to the initial 300 K CO2 distributions, and the

  15. Bipartite stripe-like order of magneto-crystalline structure in Fe-based superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Yazdani, A., E-mail: Yazdania@modares.ac.ir; Hesani, M.

    2017-01-01

    Emergence of superconductivity in the iron-based superconductor of “LaFeAsO” is a consequence of the characteristic behavior of antiferromagnetic structure at different triplet critical points. Here, we studied x{sub 2}{sup c} (highest concentration bound) = 0.5. A new second antiferromagnetic (AFM) structure was found that is developed for three different geometrical arrangements of O/H, resulting in three different antiferromagnetic structures at x{sub 2}{sup c} = 0.5. Both crystal and magnetic orderings are a consequence of the stripe-like ordering in the stripe configuration of “H” and “O”. Moreover, in our calculation a strong correlation was obtained between the magnetic and geometrical structures, resulting in the non-uniform magnetic moments of ∼1.30 μβ (AFM1-1) and ∼1.66 μβ (AFM1-3). This phenomenon results in the Jahn-Teller distortion, reflected in the non-uniformity of spin-induced distribution, in the range of 1.07 μβ close to “H” and 1.53 μβ close to “O”, in order to stabilize the ground state of the magneto-crystalline structure. This newly found second antiferromagnetic ordering behaves as the ground state with a lower cohesive energy, resulting in a lower magnetic moment. The effects are more pronounced in the displacement of atomic positions, reflecting in the repulsion of intra-layer La atoms from each other and the attraction of inter-layer Fe atoms toward each other, in direction to induce the anisotropy variable of η ≈ 0.78. - Highlights: • A new second antiferromagnetic structure was found. • Both crystal and magnetic orderings are a consequence of stripe-like ordering. • A strong correlation between the magnetic and geometrical structures was obtained. • Decrease of asymmetrical magnetic moment in direction to the decreased energy. • The effects are more pronounced on the displacement of topological atomic position.

  16. Appraisal of wheat germplasm for adult plant resistance against stripe rust

    Directory of Open Access Journals (Sweden)

    Saleem Kamran

    2015-12-01

    Full Text Available The resurgence of wheat stripe rust is of great concern for world food security. Owing to resistance breakdown and the appearance of new virulent high-temperature adapted races of Puccinia striiformis f. sp. tritici (Pst, many high yielding commercial varieties in the country lost their yield potential. Searching for new sources of resistance is the best approach to mitigate the problem. Quantitative resistance (partial or adult plant or durable resistance is reported to be more stable than race specific resistance. In the current perusal, a repertoire of 57 promising wheat lines along with the KLcheck line Morocco, developed through hybridisation and selection of local and international lines with International Maize and Wheat Improvement Center (CIMMYT origin, were evaluated under natural field conditions at Nuclear Institute for Agriculture and Biology (NIAB during the 2012−2013 and 2013−2014 time periods. Final rust severity (FRS, the area under the rust progress curve (AURPC, the relative area under the rust progress curve (rAURPC, and the coefficient of infection (CI were unraveled to infer the level of quantitative resistance. Final rust severity was recorded when the susceptible check exhibited 100% severity. There were 21 lines which were immune (no disease, 16 which were resistant, five moderately resistant, two resistant-to-moderately resistant, one moderately resistant-to-moderately susceptible, 5 moderately susceptible-to-susceptible, one moderately susceptible, and six exhibited a susceptible response. Nevertheless, 51 lines exhibited a high level of partial resistance while the three lines, NW-5-1212-1, NW-7-30-1, and NW-7-5 all showed a moderate level of partial resistance based on FRS, while 54 lines, on the basis of AURPC and rAURPC, were identified as conferring a high level of partial resistance. Moreover, adult plant resistance was conferred by 47 wheat lines, based on CI value. It was striking that, 13 immune lines

  17. THE 31 DEG{sup 2} RELEASE OF THE STRIPE 82 X-RAY SURVEY: THE POINT SOURCE CATALOG

    Energy Technology Data Exchange (ETDEWEB)

    LaMassa, Stephanie M.; Urry, C. Megan; Ananna, Tonima; Civano, Francesca; Marchesi, Stefano; Pecoraro, Robert [Yale Center for Astronomy and Astrophysics, Physics Department, P.O. Box 208120, New Haven, CT 06520 (United States); Cappelluti, Nico; Comastri, Andrea; Brusa, Marcella [INAF-Osservatorio Astronomico di Bologna, via Ranzani 1, I-40127 Bologna (Italy); Böhringer, Hans; Chon, Gayoung [Max-Planck-Institut für extraterrestrische Physik, D-85748 Garching (Germany); Glikman, Eilat [Department of Physics, Middlebury College, Middlebury, VT 05753 (United States); Richards, Gordon [Department of Physics, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104 (United States); Cardamone, Carie [Department of Math and Science, Wheelock College, 200 Riverway, Boston, MA 02215 (United States); Farrah, Duncan [Department of Physics MC 0435, Virginia Polytechnic Institute and State University, 850 West Campus Drive, Blacksburg, VA 24061 (United States); Gilfanov, Marat [Max-Planck Institut für Astrophysik, Karl-Schwarzschild-Str. 1, Postfach 1317, D-85741 Garching (Germany); Green, Paul [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Komossa, S. [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany); Lira, Paulina [Departamento de Astronomia, Universidad de Chile, Camino del Observatorio 1515, Santiago (Chile); Makler, Martin [Centro Brasileiro de Pesquisas Fisicas, Rua Dr Xavier Sigaud 150, Rio de Janeiro, RJ 22290-180 (Brazil); and others

    2016-02-01

    We release the next installment of the Stripe 82 X-ray survey point-source catalog, which currently covers 31.3 deg{sup 2} of the Sloan Digital Sky Survey (SDSS) Stripe 82 Legacy field. In total, 6181 unique X-ray sources are significantly detected with XMM-Newton (>5σ) and Chandra (>4.5σ). This catalog release includes data from XMM-Newton cycle AO 13, which approximately doubled the Stripe 82X survey area. The flux limits of the Stripe 82X survey are 8.7 × 10{sup −16} erg s{sup −1} cm{sup −2}, 4.7 × 10{sup −15} erg s{sup −1} cm{sup −2}, and 2.1 × 10{sup −15} erg s{sup −1} cm{sup −2} in the soft (0.5–2 keV), hard (2–10 keV), and full bands (0.5–10 keV), respectively, with approximate half-area survey flux limits of 5.4 × 10{sup −15} erg s{sup −1} cm{sup −2}, 2.9 × 10{sup −14} erg s{sup −1} cm{sup −2}, and 1.7 × 10{sup −14} erg s{sup −1} cm{sup −2}. We matched the X-ray source lists to available multi-wavelength catalogs, including updated matches to the previous release of the Stripe 82X survey; 88% of the sample is matched to a multi-wavelength counterpart. Due to the wide area of Stripe 82X and rich ancillary multi-wavelength data, including coadded SDSS photometry, mid-infrared WISE coverage, near-infrared coverage from UKIDSS and VISTA Hemisphere Survey, ultraviolet coverage from GALEX, radio coverage from FIRST, and far-infrared coverage from Herschel, as well as existing ∼30% optical spectroscopic completeness, we are beginning to uncover rare objects, such as obscured high-luminosity active galactic nuclei at high-redshift. The Stripe 82X point source catalog is a valuable data set for constraining how this population grows and evolves, as well as for studying how they interact with the galaxies in which they live.

  18. Na(v)1.8 channelopathy in mutant mice deficient for myelin protein zero is detrimental to motor axons

    DEFF Research Database (Denmark)

    Moldovan, Mihai; Alvarez Herrero, Susana; Pinchenko, Volodymyr

    2011-01-01

    deficient homozygous mutants to an extent that precipitates conduction failure in severely affected axons. Our data suggest that a Na(V)1.8 channelopathy contributed to the poor motor function of protein zero deficient homozygous mutants, and that the conduction failure was associated with partially...

  19. 76 FR 13082 - Amendment of VOR Federal Airways V-1, V-7, V-11 and V-20; Kona, HI

    Science.gov (United States)

    2011-03-10

    ... V-20; Kona, HI AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends four VHF Omnidirectional Range (VOR) Federal airways in the vicinity of Kona, HI; V- 1, V-7... Keahole Airport property Kailua-Kona, HI. This will enhance the management of aircraft operations over...

  20. Development of a human vasopressin V-1a-receptor antagonist from an evolutionary-related insect neuropeptide

    Czech Academy of Sciences Publication Activity Database

    Di Giglio, M. G.; Muttenthaler, M.; Harpsoe, K.; Liutkeviciute, Z.; Keov, P.; Eder, T.; Rattei, T.; Arrowsmith, S.; Wray, S.; Marek, Aleš; Elbert, Tomáš; Alewood, P. F.; Gloriam, D. E.; Gruber, C. W.

    2017-01-01

    Roč. 7, Feb 1 (2017), č. článku 41002. ISSN 2045-2322 Institutional support: RVO:61388963 Keywords : neuropeptide * inotocin * V1aR-antagonist Subject RIV: CE - Biochemistry OBOR OECD: Biochemistry and molecular biology Impact factor: 4.259, year: 2016 https://www.nature.com/articles/srep41002

  1. Transcriptional and electrophysiological consequences of KChIP2-mediated regulation of CaV1.2

    DEFF Research Database (Denmark)

    Thomsen, Morten B; Foster, Erika; Nguyen, Katherine H

    2009-01-01

    Potassium channel interacting proteins (KChIP) are Ca(2+)-binding proteins that originally were identified as auxiliary subunits for K(V)4 channels. K(V)4 channels encode the voltage gated A-current (I(A)) in neuronal tissue and the fast, transient outward current (I(to,f)) in cardiac tissue....... Recently, we have reported that KChIP2 functionally modulates the cardiac Ca(V)1.2-governed L-type Ca(2+) current (I(Ca,L)) through a direct interaction between KChIP2 and the amino-terminus of Ca(V)1.2. Here, we show that KChIP2 and Ca(V)1.2 co-immunoprecipitate enhancing the biochemical support for our...... previous finding. Using gene-chip and real-time PCR techniques, we find that KChIP2(-/-) mice have an increased transcriptional activity of the calcium channel beta(2) subunit, CACNB2, whereas the expression of Ca(V)1.2 is preserved. Although I(to,f) is absent and I(Ca,L) is decreased in myocytes from KCh...

  2. Stability of the Bet v 1 cross-reactive allergens Api g 1 and Dau c 1 : a biophysical approach

    NARCIS (Netherlands)

    Bollen, M.A.

    2009-01-01

    The allergen Bet v 1 is known as the primary sensitizer for birch pollen-related food allergy and is responsible for IgE cross-reactivity to pathogenesis-related 10 (PR-10) proteins from, in particular, fruits from the Rosaceae and vegetables from the Apiaceae families. The allergenic potential of

  3. Functional alterations of V1 cortex in patients with primary open angle glaucoma using functional MRI retinotopic mapping

    International Nuclear Information System (INIS)

    Shi Linping; Cai Ping; Li Changying; Li Xueqin; Xie Bing; Li Sha; Liu Ting; Chen Xing; Shi Yanshu; Wang Jian

    2011-01-01

    Objective: To evaluate the functional changes of visual cortex (V1) in patients with primary open angle glaucoma (POAG) by fMRI retinotopic mapping technology. Methods: Fifteen POAG patients and 15 healthy volunteers underwent stimulations with fMRI retinotopic mapping stimulus and contrast-reversing checkerboard patterns stimulus on a Siemens Trio 3.0 T MRI whole-body scanner for functional data collection. Comparisons of V1 fMRI responses between the glaucomatous eyes and the healthy eyes of the patients were carried out using paired samples t-test, while independent samples t-test was used to compare V1 fMRI responses and activations between the healthy eyes of patients and the age-, gender- and side- matched eyes of normal people. Differences of V1 cortical functions and visual functions were analyzed by linear correlation analysis when the glaucomatous and the healthy eyes were simulated individually., Results: (1) V1 fMRI responses of the individually stimulated glaucomatous eyes [(1.24±0.72)%] were weaker than those of the healthy eyes [(2.18±0.93)%] (t=4.757, P 0.05). (2) Differences of V1 cortical functions were negatively correlated with those of visual functions in the individually stimulated glaucomatous and healthy eyes (r=-0.887, P< 0.01). (3) The activated area indexes of V1 cortexes in the healthy eyes from patients (0.72±0.12) were lower than those in the matched eyes of normal people (0.85±0.09) (t=-3.801, P<0.01) . Conclusion: Cortical function impairment was in accordance with visual function impairment in glaucoma. Located and quantified measurement with fMRI retinotopic mapping was a useful method for clinical follow-up and evaluation of functional alteration of glaucomatous visual cortex, and a potentially useful means of studying trans-synaptic degeneration of visual pathways of in vivo glaucoma. (authors)

  4. Endocrinology of sociality: comparisons between sociable and solitary individuals within the same population of African striped mice.

    Science.gov (United States)

    Schoepf, Ivana; Schradin, Carsten

    2013-06-01

    The social organization of species ranges from solitary-living to complex social groups. While the evolutionary reasons of group-living are well studied, the physiological mechanisms underlying alternative social systems are poorly understood. By studying group-living and solitary individuals of the same species, we can determine hormonal correlates of sociality without the problem of confounding phylogenetic factors. The African striped mouse (Rhabdomys pumilio) is a socially flexible species, which can be solitary or alternatively form complex family groups, depending on population density and the extent of reproductive competition. We predicted group-living striped mice to show signs of reproductive suppression and social stress, resulting in higher corticosterone but lower testosterone levels when compared to solitary-living individuals. To determine whether differences in social organization correlated with hormonal differences, we collected blood samples from free-living striped mice during four breeding seasons when we experimentally induced solitary-living in philopatric individuals by locally reducing population density. Striped mice that were group-living did not change their corticosterone or estosterone levels during the study, indicating that there was no temporal effect during the breeding season. Striped mice of both sexes had significantly lower corticosterone levels after switching from group- to solitary-living. Solitary males - but not solitary females - had higher testosterone levels than group-living conspecifics. Our results suggest that group-living results in physiological stress and can induce reproductive suppression, at least in philopatric males. The switch to solitary-living may thus be a tactic to avoid reproductive competition within groups, and is associated with decreased stress hormone levels and onset of independent reproduction. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Capping protein regulatory cycle driven by CARMIL and V-1 may promote actin network assembly at protruding edges.

    Science.gov (United States)

    Fujiwara, Ikuko; Remmert, Kirsten; Piszczek, Grzegorz; Hammer, John A

    2014-05-13

    Although capping protein (CP) terminates actin filament elongation, it promotes Arp2/3-dependent actin network assembly and accelerates actin-based motility both in vitro and in vivo. In vitro, capping protein Arp2/3 myosin I linker (CARMIL) antagonizes CP by reducing its affinity for the barbed end and by uncapping CP-capped filaments, whereas the protein V-1/myotrophin sequesters CP in an inactive complex. Previous work showed that CARMIL can readily retrieve CP from the CP:V-1 complex, thereby converting inactive CP into a version with moderate affinity for the barbed end. Here we further clarify the mechanism of this exchange reaction, and we demonstrate that the CP:CARMIL complex created by complex exchange slows the rate of barbed-end elongation by rapidly associating with, and dissociating from, the barbed end. Importantly, the cellular concentrations of V-1 and CP determined here argue that most CP is sequestered by V-1 at steady state in vivo. Finally, we show that CARMIL is recruited to the plasma membrane and only at cell edges undergoing active protrusion. Assuming that CARMIL is active only at this location, our data argue that a large pool of freely diffusing, inactive CP (CP:V-1) feeds, via CARMIL-driven complex exchange, the formation of weak-capping complexes (CP:CARMIL) at the plasma membrane of protruding edges. In vivo, therefore, CARMIL should promote Arp2/3-dependent actin network assembly at the leading edge by promoting barbed-end capping there.

  6. Systematic Study of Binding of μ-Conotoxins to the Sodium Channel NaV1.4

    Directory of Open Access Journals (Sweden)

    Somayeh Mahdavi

    2014-12-01

    Full Text Available Voltage-gated sodium channels (NaV are fundamental components of the nervous system. Their dysfunction is implicated in a number of neurological disorders, such as chronic pain, making them potential targets for the treatment of such disorders. The prominence of the NaV channels in the nervous system has been exploited by venomous animals for preying purposes, which have developed toxins that can block the NaV channels, thereby disabling their function. Because of their potency, such toxins could provide drug leads for the treatment of neurological disorders associated with NaV channels. However, most toxins lack selectivity for a given target NaV channel, and improving their selectivity profile among the NaV1 isoforms is essential for their development as drug leads. Computational methods will be very useful in the solution of such design problems, provided accurate models of the protein-ligand complex can be constructed. Using docking and molecular dynamics simulations, we have recently constructed a model for the NaV1.4-μ-conotoxin-GIIIA complex and validated it with the ample mutational data available for this complex. Here, we use the validated NaV1.4 model in a systematic study of binding other μ-conotoxins (PIIIA, KIIIA and BuIIIB to NaV1.4. The binding mode obtained for each complex is shown to be consistent with the available mutation data and binding constants. We compare the binding modes of PIIIA, KIIIA and BuIIIB to that of GIIIA and point out the similarities and differences among them. The detailed information about NaV1.4-μ-conotoxin interactions provided here will be useful in the design of new NaV channel blocking peptides.

  7. Insecticide pyrethroids in liver of striped dolphin from the Mediterranean Sea.

    Science.gov (United States)

    Aznar-Alemany, Òscar; Giménez, Joan; de Stephanis, Renaud; Eljarrat, Ethel; Barceló, Damià

    2017-06-01

    Pyrethroid pesticides were analysed in liver of striped dolphin (Stenella coeruleoalba) from the Alboran Sea (south of Spain, Mediterranean Sea). The occurrence and bioaccumulation of pyrethroid insecticides in marine mammal tissues from the northern hemisphere had never been determined before. Pyrethroids were detected in 87% of the specimens with a mean total concentration of 300 ng g -1 lw ± 932 (range 2.7-5200 ng g -1 lw). Permethrin and tetramethrin were the main contributors to the pyrethroid profiles, with enantiospecific accumulation for the first and isomer specific accumulation for the latter. Bioaccumulation of pyrethroids was unlike that of persistent organic pollutants (POPs), as pyrethroid concentrations were not correlated to the maturity stage of the specimens. Concentrations slightly increased from calves to juveniles, whereas juveniles presented similar concentrations to adults. Metabolization of pyrethroids after achieving sexual maturity might account for this pattern. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Ladies in stripes: taxonomic confusion in a potential mimicry complex among Wallacean Coccinellidae (Coleoptera: Coccinellidae).

    Science.gov (United States)

    Li, Jiahui; Tomaszewska, Wioletta; Pang, Hong; Ślipiński, Adam

    2014-12-24

    Two species of ladybird beetles, one belonging to Phrynocaria Timberlake (Coccinellni) and the second to Chilocorus Leach (Chilocorini) collected by R.A. Wallace in the Maluku Islands (Indonesia) have identical body size and colour pattern with longitudinal stripes on elytra. Their external features were so similar that G.R. Crotch included both of them in the type series of Chilocorus wallacii Crotch, 1874. The specimen designated as the lectotype of Chilocorus wallacii belongs to Phrynocaria. Coelophora wallacii Crotch, 1874 is also transferred to Phrynocaria (new comb.) and becomes senior homonym and Phrynocaria crotchi new name is proposed for the secondary junior homonym. Chilocorus crotchi sp. nov. is described for the taxon misidentified as Chilocorus wallacii Crotch.

  9. Kinematics and energetic benefits of schooling in the labriform fish, striped surfperch Embiotoca lateralis

    DEFF Research Database (Denmark)

    Johansen, J. L.; Vaknin, R.; Steffensen, John Fleng

    2010-01-01

    Schooling can provide fish with a number of behavioural and ecological advantages, including increased food supply and reduced predator risk. Previous work suggests that fish swimming using body and caudal fin locomotion may also experience energetic advantages when trailing behind neighbours....... However, little is known about the potential energetic advantages associated with schooling in fish that swim using their pectoral fins. Using the striped surfperch Embiotoca lateralis, a labriform fish that swims routinely with its pectoral fins, we found that pectoral fin beat frequencies were...... significantly higher for schooling individuals swimming in the front of a school relative to those swimming in the back, with trailing individuals benefiting from a 14.9 +/- 3.2% reduction in fin beat frequency (mean +/- SE). Trailing fish were estimated to benefit from a 25.6% reduction in oxygen consumption...

  10. Transmission Biology of Rice Stripe Mosaic Virus by an Efficient Insect Vector Recilia dorsalis (Hemiptera: Cicadellidae

    Directory of Open Access Journals (Sweden)

    Xin Yang

    2017-12-01

    Full Text Available Rice stripe mosaic virus (RSMV is a newly discovered species of cytorhabdovirus infecting rice plants that is transmitted by the leafhopper Recilia dorsalis. In this study, the transmission characteristics of RSMV by R. dorsalis were investigated. Under suitable growth conditions for R. dorsalis, the RSMV acquisition rate reached 71.9% in the second-generation population raised on RSMV-infected rice plants. The minimum acquisition and inoculation access periods of R. dorsalis were 3 and 30 min, respectively. The minimum and maximum latent transmission periods of RSMV in R. dorsalis were 6 and 18 d, respectively, and some R. dorsalis intermittently transmitted RSMV at 2–6 d intervals. Our findings revealed that the virus can replicate in the leafhopper body, but is likely not transovarially transmitted to offspring. These transmission characteristics will help guide the formulation of RSMV prevention and control strategies.

  11. A Piston-Rotaxane with Two Potential Stripes: Force Transitions and Yield Stresses

    Directory of Open Access Journals (Sweden)

    Edith M. Sevick

    2013-10-01

    Full Text Available We examine a rod piston-rotaxane system, where the positions of several mobile rings on the axle are controlled by an external force acting on one of the rings. This allows us to access the translational entropy of the rings. For a simple rotaxane molecule with an axle that has uniform ring-axle interactions along its length, the molecule behaves like a miniature piston filled with a one-dimensional ideal gas. We then examine the effect of two stripes on the axle, having different ring-axle interactions with the mobile rings, so that one section is of high energy (repulsive for the rings and another section is of lower energy (or attractive. This kind of rotaxane can exhibit rapid changes in displacement or force, and in particular, this molecule can exhibit a yield stress in which the piston suddenly compresses under a small increase in the applied force.

  12. Complete mitochondrial genome of the striped scat Selenotoca multifasciata (Perciformes: Scatophagidae).

    Science.gov (United States)

    Liu, Zhenhao; Mu, Xingjiang; Li, Hong; Gui, Lang; Zeng, Wengang; Zhang, Junbin

    2016-07-01

    The striped scat Selenotoca multifasciata is an ornamental and commercial fish in Asia. In the present study, we sequenced and annotated the complete mitochondrial genome of Selenotoca multifasciata. Its total length is 16,646 bp, and the mitochondrial genome is composed of 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes and a non-coding control region. ND6 and eight tRNA genes were encoded on the light strand, whereas the remaining genes located on the heavy strand (H-strand). All the 16 mitochondrial genomes of the suborder Acanthuroidei available in GenBank were employed for phylogenetic analysis, and the result showed a close relationship between Selenotoca multifasciata and Scatophagus argus. This mitochondrial information may benefit relative ecological and phylogenetic studies.

  13. IGF-I and branchial IGF receptor expression and localization during salinity acclimation in striped bass

    DEFF Research Database (Denmark)

    Tipsmark, Christian Kølbaek; Luckenbach, John Adam; Madsen, Steffen

    2007-01-01

    The initial response of the IGF-I system and the expression and cellular localization of IGF type-I receptor (IGF-IR) were studied in the gill of a euryhaline teleost during salinity acclimation. Exposure of striped bass (Morone saxatilis) to hyperosmotic and hypoosmotic challenges induced small......, transitory (liver IGF-I mRNA levels after SW transfer, suggesting that decreased plasma levels...... in either plasma IGF-I, liver, or gill IGF-I mRNA, or gill IGF-IR mRNA levels. In a separate experiment, FW-acclimated fish were injected with saline or IGF-I prior to a 24-h SW challenge. Rapid regain of osmotic balance following SW transfer was hindered by IGF-I. Immunohistochemistry revealed...

  14. Graphically characterizing the movement of a rabid striped skunk epizootic across the landscape in northwestern Wyoming.

    Science.gov (United States)

    Ramey, Craig A; Mills, Kenneth W; Fischer, Justin W; McLean, Robert G; Fagerstone, Kathleen A; Engeman, Richard M

    2013-09-01

    A striped skunk (Mephitis mephitis) rabies epizootic in northwestern Wyoming was studied from the Index Case in 1988 to the last case in 1993, and possibly is the first rabies epizootic in a previously rabies-free zone monitored from beginning to end. The 843 km(2) study area comprised skunk habitat along 90 km of Shoshone River's floodplain from Bighorn Lake upstream to Cody. Of 1,015 skunks tested, 215 were rabies-positive. Integrating spatial and temporal data from positive cases, we analyzed the epizootic's movements and dynamics at 6-month intervals using multivariate movement maps, a new multivariate descriptive methodology presented here to demonstrate the epizootic's directional flow, while illustrating areas with higher case densities (i.e., wave crests). This approach should help epidemiologists and public health officials to better understand future rabies epizootics.

  15. The complete mitochondrial genome of the critically endangered Vietnamese three-striped box turtle (Testudines: Geoemydidae).

    Science.gov (United States)

    Li, Wei; Zhao, Jian; Shi, Yan; Xiao, Feng-Fang; Zhang, Xin-Cheng; Zhu, Xin-Ping

    2015-01-01

    The complete mitochondrial genome of the Vietnamese three-striped box turtle (Cuora cyclornata) was first determined in this study. It was a circular molecule of 16,594 bp in length, consisting of 37 genes typically found in other vertebrates. The AT content of the overall base composition of the whole mitogenome was 60.39%, while the control region was 70.23%. Two ETAS and 4 CSBs were identified, while a remarkable feature was found in the control region: a large number of (TTATTATA)10 direct tandem repeats followed by (TTATA)n (n=10, 8 and 1), which were spaced into three domains by (TA)n (n=1, 1 and 2). The sequence information could play an important role in the study of phylogenetic relationships in turtles and preservation of genetic resources for helping conservation of the endangered species.

  16. Simple and Rapid Detection for Rice stripe virus Using RT-PCR and Porous Ceramic Cubes

    Directory of Open Access Journals (Sweden)

    Su-Bin Hong

    2015-12-01

    Full Text Available A rapid and simple RT-PCR diagnosis method for detection of Rice stripe virus (RSV, one of major virus infecting rice, was developed using porous ceramic cubes in this study. The porous ceramic cube can rapidly absorb biological molecules such as small-sized proteins and nucleic acid fragments into its pores. We examined whether this ability of porous ceramic cubes could be applied for isolating viral nucleic acids or particles from the RSV- infected plant tissues. In this study, we found that the porous ceramic cube was capable of absorbing a detection level of viruses from the rice tissues infected with RSV and established RT-PCR-based RNA diagnosis method using porous ceramic cubes.

  17. Gait transition and oxygen consumption in swimming striped surfperch Embiotoca lateralis Agassiz

    DEFF Research Database (Denmark)

    Cannas, M.; Schaefer, J.; Domenici, P.

    2006-01-01

    A flow-through respirometer and swim tunnel was used to estimate the gait transition speed (Up-c) of striped surfperch Embiotoca lateralis, a labriform swimmer, and to investigate metabolic costs associated with gait transition. The Up-c was defined as the lowest speed at which fish decrease...... the use of pectoral fins significantly. While the tail was first recruited for manoeuvring at relatively low swimming speeds, the use of the tail at these low speeds [as low as 0·75 body (fork) lengths s-1, LF s-1) was rare (..., either in addition to pectoral fins or during burst-and-coast mode. Oxygen consumption increased exponentially with swimming speeds up to gait transition, and then levelled off. Similarly, cost of transport (CT) decreased with increasing speed, and then levelled off near Up-c. When speeds =Up...

  18. Magnetic stripe domains of [Pt/Co/Cu]10 multilayer near spin reorientation transition

    Directory of Open Access Journals (Sweden)

    L. Sun

    2016-05-01

    Full Text Available The dependence of magnetic anisotropy, magnetic domain patterns and magnetization reversal processes in [Pt/Co(tCo/Cu]10 film stack epitaxied on Cu (111 substrate have been studied as a function of the Co layer thickness tCo, by magneto-optic polar Kerr magnetometry and microscopy. We find the film undergoes spin reorientation transition from out-of-plane to in-plane as tCo increases. The SRT thickness is verified by Rotating-field Magneto-Optic Kerr effect method. The film exhibits the stripe domain structures at remanence with the width decreasing while tCo approaches SRT. As demonstrated by the first order reversal curve measurement, the magnetization reversal process encompasses irreversible domain nucleation, domain annihilation at large field and reversible domain switching near remanence.

  19. Nocardia seriolae infection in the three striped tigerfish, Terapon jarbua (Forsskål).

    Science.gov (United States)

    Wang, P-C; Chen, S-D; Tsai, M-A; Weng, Y-J; Chu, S-Y; Chern, R-S; Chen, S-C

    2009-04-01

    An epizootic in pond cultured three striped tigerfish, Terapon jarbua, in Taiwan was caused by Nocardia seriolae. Diseased fish first showed clinical signs and mortalities in February and March 2003. The cumulative mortality within 2 months was 2.4% (1200 of 50 000) and affected fish were 7 months old with total lengths from 18 to 25 cm. Most affected fish were pale and lethargic with haemorrhages and ulcers on the skin. The most significant gross pathological changes were varying degrees of ascites and enlargement of the spleen, kidney and liver. Obvious white nodules, varying in size, were found in these organs. Bacteria were either coccal or filamentous in appearance, with bead-like forms. Isolates from diseased fish were characterized using the API ZYM (Analytical profile index; Bio Mérieux, France) systems and conventional tests and identified as Nocardia sp. The isolate was designated NS127 and was confirmed as N. seriolae by a polymerase chain reaction assay that gave the expected specific 432 bp amplicon. In addition, its 16S rDNA sequence gave 100% sequence identity with N. seriolae. A partial sequence of the 16S rRNA gene, heat shock protein gene and RNA polymerase gene (rpo B) of NS127 and the type strain of N. seriolae BCRC 13745 formed a monophyletic clade with a high sequence similarity and bootstrap value of 99.9%. White nodules induced in experimental fish were similar to naturally infected cases and N. seriolae was re-isolated on brain heart infusion agar. This is the first report of N. seriolae-infection in three striped tigerfish in aquaculture.

  20. Effect of zinc sulphate on gelling properties of phosphorylated protein isolate from yellow stripe trevally.

    Science.gov (United States)

    Arfat, Yasir Ali; Benjakul, Soottawat

    2013-12-01

    Impacts of zinc sulphate (ZnSO4) (0-140 μmol/kg) on gel properties of yellow stripe trevally surimi added with sodium tripolyphosphate (STPP) (0.25% and 0.5%, w/w) and protein isolate phosphorylated with STPP at 0.25% and 0.5% (w/w) were studied. Gels from surimi added with 60 μmol ZnSO4/kg in the absence and presence of 0.5% STPP had the increases in breaking force and deformation by 20.9% and 33.3%, and 11.6% and 18.6%, respectively, compared with the control surimi gel (without additives). Gel of protein isolate phosphorylated with 0.5% STPP containing 100 μmol ZnSO4/kg had the increases in breaking force and deformation by 14.87% and 5.6%, respectively, compared with the gel from non-phosphorylated protein isolate at the same ZnSO4 level, suggesting that the phosphorylated protein isolate was more crosslinked by Zn(2+). The addition of ZnSO4 at the suitable level lowered the expressible moisture content, but increased whiteness of surimi or protein isolate gels (Pisolate added with ZnSO4, regardless of phosphates incorporated. Microstructure study revealed that a gel having highly interconnected and denser network with smaller voids was formed when protein isolate phosphorylated with 0.5% STPP was added with ZnSO4 at a level of 100 μmol/kg. Thus, gel with improved properties could be obtained from protein isolate from yellow stripe trevally phosphorylated with STPP in conjunction with addition of ZnSO4 at an appropriate level. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Effect of the tiger stripes on the tidal deformation of Enceladus

    Science.gov (United States)

    Soucek, Ondrej; Hron, Jaroslav; Behounkova, Marie; Cadek, Ondrej

    2016-10-01

    The south polar region of Saturn's moon Enceladus has been subjected to a thorough scientific scrutiny since the Cassini mission discovery of an enigmatic system of fractures informally known as "tiger stripes". This fault system is possibly connected to the internal water ocean and exhibits a striking geological activity manifesting itself in the form of active water geysers on the moon's surface.The effect of the faults on periodic tidal deformation of the moon has so far been neglected because of the difficulties associated with the implementation of fractures in continuum mechanics models. Employing an open source finite element FEniCS package, we provide a numerical estimate of the maximum possible impact of the tiger stripes on the tidal deformation and the heat production in Enceladus's ice shell by representing the faults as narrow zones with negligible frictional and bulk resistance passing vertically through the whole shell.For a uniform ice shell thickness of 25 km, consistent with the recent estimate of libration, and for linear elastic rheology, we demonstrate that the faults can dramatically change the distribution of stress and strain in Enceladus's south polar region, leading to a significant increase of the heat flux and to a complex deformation pattern in this area. We also present preliminary results studying the effects of (i) variable ice-shell thickness, based on the recent topography, gravity and libration inversion model by Čadek et al. (2016) and (ii) Maxwell viscoelastic rheology on the global tidal deformation of the ice shell.O.S. acknowledges support by the Grant Agency of the Czech Republic through the project 15-14263Y.

  2. Lateral spread of orientation selectivity in V1 is controlled by intracortical cooperativity

    Directory of Open Access Journals (Sweden)

    Frédéric eChavane

    2011-02-01

    Full Text Available Neurons in the primary visual cortex receive subliminal information originating from the periphery of their receptive fields through a variety of cortical connections. In the cat primary visual cortex, long-range horizontal axons have been reported to preferentially bind to distant columns of similar orientation preferences, whereas feedback connections from higher visual areas provide a more diverse functional input. To understand the role of these lateral interactions, it is crucial to characterize their effective functional connectivity and tuning properties. However, the overall functional impact of cortical lateral connections, whatever their anatomical origin, is unknown since it has never been directly characterized. Using direct measurements of postsynaptic integration in cat areas 17/18, we performed multi-scale assessments of the functional impact of visually driven lateral networks. Voltage-sensitive dye imaging showed that local oriented stimuli evoke an orientation-selective activity that remains confined to the cortical feedforward imprint of the stimulus. Beyond a distance of one hypercolumn, the lateral spread of cortical activity gradually lost its orientation preference approximated as an exponential with a space constant of about 1mm. Intracellular recordings showed that this loss of orientation selectivity arises from the diversity of converging synaptic input patterns originating from outside the classical receptive field. In contrast, when the stimulus size was increased, we observed orientation-selective spread of activation beyond the feedforward imprint. We conclude that stimulus-induced cooperativity enhances the long-range orientation-selective spread.

  3. Memory-guided drawing training increases Granger causal influences from the perirhinal cortex to V1 in the blind.

    Science.gov (United States)

    Cacciamani, Laura; Likova, Lora T

    2017-05-01

    The perirhinal cortex (PRC) is a medial temporal lobe structure that has been implicated in not only visual memory in the sighted, but also tactile memory in the blind (Cacciamani & Likova, 2016). It has been proposed that, in the blind, the PRC may contribute to modulation of tactile memory responses that emerge in low-level "visual" area V1 as a result of training-induced cortical reorganization (Likova, 2012, 2015). While some studies in the sighted have indicated that the PRC is indeed structurally and functionally connected to the visual cortex (Clavagnier, Falchier, & Kennedy, 2004; Peterson, Cacciamani, Barense, & Scalf, 2012), the PRC's direct modulation of V1 is unknown-particularly in those who lack the visual input that typically stimulates this region. In the present study, we tested Likova's PRC modulation hypothesis; specifically, we used fMRI to assess the PRC's Granger causal influence on V1 activation in the blind during a tactile memory task. To do so, we trained congenital and acquired blind participants on a unique memory-guided drawing technique previously shown to result in V1 reorganization towards tactile memory representations (Likova, 2012). The tasks (20s each) included: tactile exploration of raised line drawings of faces and objects, tactile memory retrieval via drawing, and a scribble motor/memory control. FMRI before and after a week of the Cognitive-Kinesthetic training on these tasks revealed a significant increase in PRC-to-V1 Granger causality from pre- to post-training during the memory drawing task, but not during the motor/memory control. This increase in causal connectivity indicates that the training strengthened the top-down modulation of visual cortex from the PRC. This is the first study to demonstrate enhanced directed functional connectivity from the PRC to the visual cortex in the blind, implicating the PRC as a potential source of the reorganization towards tactile representations that occurs in V1 in the blind brain

  4. Mechanism and prognostic role of qR in V1in patients with pulmonary arterial hypertension.

    Science.gov (United States)

    Waligóra, Marcin; Kopeć, Grzegorz; Jonas, Kamil; Tyrka, Anna; Sarnecka, Agnieszka; Miszalski-Jamka, Tomasz; Urbańczyk-Zawadzka, Małgorzata; Podolec, Piotr

    The presence of qR pattern in lead V 1 of the 12-lead surface ECG has been proposed as a risk marker of death in patients with pulmonary arterial hypertension (PAH). We aimed to validate these findings in the modern era of PAH treatment and additionally to assess the relation of qR in V 1 to PAH severity. We also investigated the possible mechanisms underlying this ECG sign. Consecutive patients with PAH excluding patients with congenital heart defect were recruited between February 2008 and January 2016. A 12-lead standard ECG was acquired and analyzed for the presence of qR in V 1 and other potential prognostic patterns. Cardiac magnetic resonance and echocardiography were used for structural (masses and volumes) and functional (ejection fraction, eccentricity index) characterization of left (LV) and right (RV) ventricles. Standard markers of PAH severity were also assessed. We enrolled 66 patients (19 males), aged 50.0±15.7years with idiopathic PAH (n=52) and PAH associated with connective tissue disease (n=14). qR in V 1 was present in 26(39.4%) patients and was associated with worse functional capacity, hemodynamics and RV function. The main structural determinants of qR in V 1 were RV to LV volume ratio (OR: 3.99; 95% CI: 1.47-10.8, p=0.007) and diastolic eccentricity index (OR: 15.0; 95% CI: 1.29-175.5, p=0.03). During observation time of 30.5±19.4months, 20 (30.3%) patient died, 13 (50%) patients with qR and 7 (17.5%) patients without qR pattern. Electrocardiographic determinants of survival were qR (HR: 3.06, 95% CI: 1.21-7.4; p=0.02) and QRS duration (HR: 1.02, 95% CI: 1.01-1.04; p=0.01). Presence of qR in V 1 reflects RV dilation and diastolic interventricular septum flattening. It is a sign of advanced PAH and predicts the risk of death in this population. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. GNSS Software Receiver for UAVs

    DEFF Research Database (Denmark)

    Olesen, Daniel Madelung; Jakobsen, Jakob; von Benzon, Hans-Henrik

    2016-01-01

    This paper describes the current activities of GPS/GNSS Software receiver development at DTU Space. GNSS Software receivers have received a great deal of attention in the last two decades and numerous implementations have already been presented. DTU Space has just recently started development of ...... of our own GNSS software-receiver targeted for mini UAV applications, and we will in in this paper present our current progress and briefly discuss the benefits of Software Receivers in relation to our research interests.......This paper describes the current activities of GPS/GNSS Software receiver development at DTU Space. GNSS Software receivers have received a great deal of attention in the last two decades and numerous implementations have already been presented. DTU Space has just recently started development...

  6. Using voltage-sensor toxins and their molecular targets to investigate NaV1.8 gating.

    Science.gov (United States)

    Gilchrist, John; Bosmans, Frank

    2017-11-29

    Voltage-gated sodium (Na V ) channel gating is a complex phenomenon which involves a distinct contribution of four integral voltage-sensing domains (VSDI, VSDII, VSDIII and VSDIV). Utilizing accrued pharmacological and structural insights, we build on an established chimera approach to introduce animal toxin sensitivity in each VSD of an acceptor channel by transferring in portable S3b-S4 motifs from the four VSDs of a toxin-susceptible donor channel (Na V 1.2). By doing so, we observe that in Na V 1.8, a relatively unexplored channel subtype with distinctly slow gating kinetics, VSDI-III participate in channel opening whereas VSDIV can regulate opening as well as fast inactivation. These results illustrate the effectiveness of a pharmacological approach to investigate the mechanism underlying gating of a mammalian Na V channel complex. © 2017 The Authors. The Journal of Physiology © 2017 The Physiological Society.

  7. High Carrier Mobility up to 1.4 cm2.V-1.s-1 in Non-Peripheral Octahexyl Phthalocyanine

    Science.gov (United States)

    Miyake, Yasuo; Shiraiwa, Youyu; Okada, Keizo; Monobe, Hirosato; Hori, Tetsuro; Yamasaki, Naoyuki; Yoshida, Hiroyuki; Cook, Michael J.; Fujii, Akihiko; Ozaki, Masanori; Shimizu, Yo

    2011-02-01

    Carrier transport properties of a non-peripherally alkyl-substituted phthalocyanine, 1,4,8,11,15,18,22,25-octahexylphthalocyanine (C6PcH2) have been investigated. The material is a low-molecular-weight organic semiconductor with high solubility for typical organic solvents and liquid crystallinity. The carrier mobility was measured in the crystal phase and the hexagonal disordered columnar (Colhd) mesophase by the time-of-flight technique. A strong negative temperature dependence was observed for the hole mobility in the crystal phase, and a maximum drift mobility of 1.4 cm2.V-1.s-1 was achieved at -15 °C. A maximum mobility of 0.5 cm2.V-1.s-1 was obtained for the electrons that had a smaller dependence.

  8. Main features of buildings and structures important to safety of units V1 and V2 of Bohunice NPP

    International Nuclear Information System (INIS)

    David, M.

    1993-01-01

    The program of seismic upgrading of Bohunice NPPs has been started in the year 1989 (after finishing of new seismic input). Since that time the seismic upgrading of Main building of NPP V1 has already been realized, structural as well as technological parts. Beside that the designs of seismic upgrading of other structures of NPP V1 and V2 have been completed. It has been proved that the seismic upgrading of NPPs with reactors WWER 440 is very complicated, but still possible, even in the case with high seismic intensity. It would be not possible to fulfill this complicated task without the help of IAEA Missions. The activities of IAEA experts in the program of Bohunice NPPs upgrading are appreciated very much

  9. Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities.

    Science.gov (United States)

    Weiss, Matthew M; Dineen, Thomas A; Marx, Isaac E; Altmann, Steven; Boezio, Alessandro; Bregman, Howard; Chu-Moyer, Margaret; DiMauro, Erin F; Feric Bojic, Elma; Foti, Robert S; Gao, Hua; Graceffa, Russell; Gunaydin, Hakan; Guzman-Perez, Angel; Huang, Hongbing; Huang, Liyue; Jarosh, Michael; Kornecook, Thomas; Kreiman, Charles R; Ligutti, Joseph; La, Daniel S; Lin, Min-Hwa Jasmine; Liu, Dong; Moyer, Bryan D; Nguyen, Hanh N; Peterson, Emily A; Rose, Paul E; Taborn, Kristin; Youngblood, Beth D; Yu, Violeta; Fremeau, Robert T

    2017-07-27

    Several reports have recently emerged regarding the identification of heteroarylsulfonamides as Na V 1.7 inhibitors that demonstrate high levels of selectivity over other Na V isoforms. The optimization of a series of internal Na V 1.7 leads that address a number of metabolic liabilities including bioactivation, PXR activation, as well as CYP3A4 induction and inhibition led to the identification of potent and selective inhibitors that demonstrated favorable pharmacokinetic profiles and were devoid of the aforementioned liabilities. The key to achieving this within a series prone to transporter-mediated clearance was the identification of a small range of optimal cLogD values and the discovery of subtle PXR SAR that was not lipophilicity dependent. This enabled the identification of compound 20, which was advanced into a target engagement pharmacodynamic model where it exhibited robust reversal of histamine-induced scratching bouts in mice.

  10. User manual of Visual Balan V. 1.0 Interactive code for water balances and refueling estimation

    International Nuclear Information System (INIS)

    Samper, J.; Huguet, L.; Ares, J.; Garcia, M. A.

    1999-01-01

    This document contains the Users Manual of Visual Balan V1.0, an updated version of Visual Balan V0.0 (Samper et al., 1997). Visual Balan V1.0 performs daily water balances in the soil, the unsaturated zone and the aquifer in a user-friendly environment which facilitates both the input data process and the postprocessing of results. The main inputs of the balance are rainfall and irrigation while the outputs are surface runoff, evapotranspiration, interception, inter flow and groundwater flow. The code evaluates all these components in a sequential manner by starting with rainfall and irrigation, which must be provided by the user, and continuing with interception, surface runoff, evapotranspiration, and potential recharge (water flux crossing the bottom of the soil). This potential recharge is the input to the unsaturated zone where water can flow horizontally as subsurface flow (inter flow) or vertically as percolation into the aquifer. (Author)

  11. Tidal-Induced Internal Ocean Waves as an Explanation for Enceladus' Tiger Stripe Pattern and Hotspot Activity

    Science.gov (United States)

    Vermeersen, B. L. A.; Maas, L. R.; van Oers, S.; Rabitti, A.; Jara-Orue, H.

    2014-12-01

    One of the most peculiar features on Saturn moon Enceladus is its so-called tiger stripe pattern at the geologically active South Polar Terrain (SPT), as first observed in detail by the Cassini spacecraft early 2005. It is generally assumed that the four almost parallel surface lines that constitute this pattern are faults in the icy surface overlying a confined salty water reservoir. Indeed, later Cassini observations have shown that salty water jets originate from the tiger stripes [e.g., Hansen et al., Science, 311, 1422-1425, 2006; Postberg et al., Nature, 474, 620-622, 2011]. More recently, Porco et al. [Astron. J., 148:45, Sep. 2014] and Nimmo et al. [Astron. J., 148:46, Sep. 2014] have reported strong evidence that the geysers are not caused by frictional heating at the surface, but that geysers must originate deeper in Enceladus' interior. Tidal flexing models, like those of Hurford et al., Nature, 447, 292-294, 2007, give a good match for the brightness variations Cassini observes, but they seem to fail to reproduce the exact timing of plume brightening. Although jet activity is thus strongly connected to tidal forcing, another mechanism must be involved as well. Last year, we formulated the original idea [Vermeersen et al., AGU Fall Meeting 2013, abstract #P53B-1848] that the tiger stripe pattern is formed and maintained by induced, tidally and rotationally driven, wave-attractor motions in the ocean underneath the icy surface of the tiger-stripe region. Such wave-attractor motions are observed in water tank experiments in laboratories on Earth and in numerical experiments [Maas et al., Nature, 338, 557-561, 1997; Drijfhout and Maas, J. Phys. Oceanogr., 37, 2740-2763, 2007; Hazewinkel et al., Phys. Fluids, 22, 107102, 2010]. The latest observations by Porco et al. and Nimmo et al. seem to be in agreement with this tidal-induced wave attractor phenomenon, both with respect to tiger stripe pattern and with respect to timing of hotspot activity. However, in

  12. Expansion of the South China Sea basin: Constraints from magnetic anomaly stripes, sea floor topography, satellite gravity and submarine geothermics

    Directory of Open Access Journals (Sweden)

    Xuezhong Yu

    2017-01-01

    Full Text Available The widely distributed E–W-trending magnetic anomaly stripes in the central basin and the N–E-trending magnetic anomaly stripes in the southwest sub-basin provide the most important evidence for Neogene expansion of the South China Sea. The expansion mechanism remains, however, controversial because of the lack of direct drilling data, non-systematic marine magnetic survey data, and irregular magnetic anomaly stripes with two obvious directions. For example, researchers have inferred different ages and episodes of expansion for the central basin and southwest sub-basin. Major controversy centers on the order of basinal expansion and the mechanism of expansion for the entire South China Sea basin. This study attempts to constrain these problems from a comprehensive analysis of the seafloor topography, magnetic anomaly stripes, regional aeromagnetic data, satellite gravity, and submarine geothermics. The mapped seafloor terrain shows that the central basin is a north-south rectangle that is relatively shallow with many seamounts, whereas the southwest sub-basin is wide in northeast, gradually narrows to the southwest, and is relatively deeper with fewer seamounts. Many magnetic anomaly stripes are present in the central basin with variable dimensions and directions that are dominantly EW-trending, followed by the NE-, NW- and NS-trending. Conversely such stripes are few in the southwest sub-basin and mainly NE-trending. Regional magnetic data suggest that the NW-trending Ailaoshan-Red River fault extends into the South China Sea, links with the central fault zone in the South China Sea, which extends further southward to Reed Tablemount. Satellite gravity data show that both the central basin and southwest sub-basin are composed of oceanic crust. The Changlong seamount is particularly visible in the southwest sub-basin and extends eastward to the Zhenbei seamount. Also a low gravity anomaly zone coincides with the central fault zone in the sub

  13. The V1 region of gp120 is preferentially selected during SIV/HIV transmission and is indispensable for envelope function and virus infection.

    Science.gov (United States)

    Li, Yanpeng; Dittmer, Ulf; Wang, Yan; Song, Jiping; Sun, Binlian; Yang, Rongge

    2016-06-01

    A transmission bottleneck occurs during each human immunodeficiency virus (HIV) transmission event, which allows only a few viruses to establish new infection. However, the genetic characteristics of the transmitted viruses that are preferentially selected have not been fully elucidated. Here, we analyzed amino acids changes in the envelope protein during simian immunodeficiency virus (SIV)/HIV deep transmission history and current HIV evolution within the last 15-20 years. Our results confirmed that the V1V2 region of gp120 protein, particularly V1, was preferentially selected. A shorter V1 region was preferred during transmission history, while during epidemic, HIV may evolve to an expanded V1 region gradually and thus escape immune recognition. We then constructed different HIV-1 V1 mutants using different HIV-1 subtypes to elucidate the role of the V1 region in envelope function. We found that the V1 region, although highly variable, was indispensable for virus entry and infection, probably because V1 deletion mutants exhibited impaired processing of gp160 into mature gp120 and gp41. Additionally, the V1 region affected Env incorporation. These results indicated that the V1 region played a critical role in HIV transmission and infection.

  14. Glycosylation of alpha(2)delta(1) subunit: a sweet talk with Ca(v)1.2 channels

    Czech Academy of Sciences Publication Activity Database

    Lazniewska, Joanna; Weiss, Norbert

    2016-01-01

    Roč. 35, č. 3 (2016), s. 239-242 ISSN 0231-5882 R&D Projects: GA ČR GA15-13556S; GA MŠk 7AMB15FR015 Institutional support: RVO:61388963 Keywords : calcium channel * Ca(v)1.2 channel * ancillary subunit * alpha(2)delta(1) subunit * glycosylation * trafficking Subject RIV: CE - Biochemistry Impact factor: 1.170, year: 2016

  15. Treatment of Na(v)1.7-mediated pain in inherited erythromelalgia using a novel sodium channel blocker.

    Science.gov (United States)

    Goldberg, Yigal Paul; Price, Nicola; Namdari, Rostam; Cohen, Charles Jay; Lamers, Mieke H; Winters, Conrad; Price, James; Young, Clint E; Verschoof, Henry; Sherrington, Robin; Pimstone, Simon Neil; Hayden, Michael Reuben

    2012-01-01

    Mutations in the SCN9A gene leading to deficiency of its protein product, Na(v)1.7, cause congenital indifference to pain (CIP). CIP is characterized by the absence of the ability to sense pain associated with noxious stimuli. In contrast, the opposite phenotype to CIP, inherited erythromelalgia (IEM), is a disorder of spontaneous pain caused by missense mutations resulting in gain-of-function in Na(v)1.7 that promote neuronal hyperexcitability. The primary aim of this study was to demonstrate that Na(v)1.7 antagonism could alleviate the pain of IEM, thereby demonstrating the utility of this opposite phenotype model as a tool for rapid proof-of-concept for novel analgesics. An exploratory, randomized, double-blind, 2-period crossover study was conducted in 4 SCN9A mutation-proven IEM patients. In each treatment period (2days), separated by a 2-day washout period, patients were orally administered XEN402 (400mg twice daily) or matching placebo. In 3 patients, pain was induced by heat or exercise during each treatment arm. A fourth patient, in constant severe pain, required no induction. Patient-reported outcomes of pain intensity and/or relief were recorded, and the time taken to induce pain was measured. The ability to induce pain in IEM patients was significantly attenuated by XEN402 compared with placebo. XEN402 increased the time to maximal pain induction and significantly reduced the amount of pain (42% less) after induction (P=.014). This pilot study showed that XEN402 blocks Na(v)1.7-mediated pain associated with IEM, thereby demonstrating target engagement in humans and underscoring the use of rare genetic disorders with mutant target channels as a novel approach to rapid proof-of-concept. Copyright © 2011 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  16. The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101.

    Directory of Open Access Journals (Sweden)

    Chloé Ackaert

    Full Text Available Allergy prevalence has increased in industrialized countries. One contributing factor could be pollution, which can cause nitration of allergens exogenously (in the air or endogenously (in inflamed lung tissue. We investigated the impact of nitration on both the structural and immunological behavior of the major birch pollen allergen Bet v 1.0101 to determine whether nitration might be a factor in the increased incidence of allergy. Bet v 1.0101 was nitrated with tetranitromethane. Immune effects were assessed by measuring the proliferation of specific T-cell lines (TCLs upon stimulation with different concentrations of nitrated and unmodified allergen, and by measurement of cytokine release of monocyte-derived dendritic cells (moDCs and primary DCs (primDCs stimulated with nitrated versus unmodified allergen. HPLC-MS, crystallography, gel electrophoresis, amino acid analysis, size exclusion chromatography and molecular dynamics simulation were performed to characterize structural changes after nitration of the allergen. The proliferation of specific TCLs was higher upon stimulation with the nitrated allergen in comparison to the unmodified allergen. An important structural consequence of nitration was oligomerization. Moreover, analysis of the crystal structure of nitrated Bet v 1.0101 showed that amino acid residue Y83, located in the hydrophobic cavity, was nitrated to 100%. Both moDCs and primDCs showed decreased production of TH1-priming cytokines, thus favoring a TH2 response. These results implicate that nitration of Bet v 1.0101 might be a contributing factor to the observed increase in birch pollen allergy, and emphasize the importance of protein modifications in understanding the molecular basis of allergenicity.

  17. High Temperature Creep of an Al-8,5Fe-1,3V-1,7Si Alloy

    Czech Academy of Sciences Publication Activity Database

    Kuchařová, Květa; Zhu, S. J.; Čadek, Josef

    2002-01-01

    Roč. 40, č. 2 (2002), s. 69-84 ISSN 0023-432X R&D Projects: GA AV ČR IBS2041001 Institutional research plan: CEZ:AV0Z2041904 Keywords : Al-8,5Fe 1,3V 1,7Si alloy * creep behavior , true threshold stress Subject RIV: JI - Composite Materials Impact factor: 0.493, year: 2002

  18. Carbides Evolution and Tensile Property of 4Cr5MoSiV1 Die Steel with Rare Earth Addition

    Directory of Open Access Journals (Sweden)

    Hanghang Liu

    2017-10-01

    Full Text Available Studies of 4Cr5MoSiV1 die steel suggest that under appropriate conditions, additions of rare earth (RE can enhance tensile property. This improvement is apparently due to the more uniform distribution of carbides and the enhancement of precipitation strengthening after RE additions. In this present work, the effect of the RE addition on the carbides evolution and tensile property of 4Cr5MoSiV1 steel with various RE contents (0, 0.018, 0.048 and 0.15 wt % were systematically investigated. The two-dimensional detection techniques such as optical microscopy (OM, scanning electron microscopy (SEM, transmission electron microscopy (TEM, and X-ray diffraction (XRD were used to investigate the carbides evolution of as-cast, annealed and tempered with RE addition. The results indicated that the carbides in 4Cr5MoSiV1 steels were modified by adding the suitable amount of RE. The eutectic structure and coarse eutectic carbides were all refining and the morphology of the annealed carbides initiated change from strip shape to ellipsoidal shape compared with the unmodified test steel (0RE. In addition, the amount of the tempered M8C7 carbides increased initially and then decreased with the alteration of RE addition from 0.018 to 0.15 wt %. Notably, the tensile test indicated that the average value of ultimate tensile strength (UTS and elongation rate of 0.048RE steel increased slightly to 1474 MPa and 15%, higher than the 1452 MPa and 12% for the unmodified test steel (0RE, respectively. Such an addition of RE (0.048 wt % would have a significant effect on the carbides evolution of as-cast, annealed and tempered and resulting in the tensile property of 4Cr5MoSiV1 die steel.

  19. VSTM-v1, a potential myeloid differentiation antigen that is downregulated in bone marrow cells from myeloid leukemia patients

    OpenAIRE

    Xie, Min; Li, Ting; Li, Ning; Li, Jinlan; Yao, Qiumei; Han, Wenling; Ruan, Guorui

    2015-01-01

    Leukocyte differentiation antigens often represent important markers for the diagnosis, classification, prognosis, and therapeutic targeting of myeloid leukemia. Herein, we report a potential leukocyte differentiation antigen gene VSTM1 (V-set and transmembrane domain-containing 1) that was downregulated in bone marrow cells from leukemia patients and exhibited a higher degree of promoter methylation. The expression level of its predominant encoded product, VSTM1-v1, was positively correlated...

  20. Biophysical characterization data of the artificial protein Octarellin V.1 and binding test with its X-ray helpers

    Directory of Open Access Journals (Sweden)

    Maximiliano Figueroa

    2016-09-01

    Full Text Available The artificial protein Octarellin V.1 (http://dx.doi.org/10.1016/j.jsb.2016.05.004 [1] was obtained through a direct evolution process over the de novo designed Octarellin V (http://dx.doi.org/10.1016/S0022-2836(0201206-8 [2]. The protein has been characterized by circular dichroism and fluorescence techniques, in order to obtain data related to its thermo and chemical stability. Moreover, the data for the secondary structure content studied by circular dichroism and infra red techniques is reported for the Octarellin V and V.1. Two crystallization helpers, nanobodies (http://dx.doi.org/10.1038/nprot.2014.039 [3] and αRep (http://dx.doi.org/10.1016/j.jmb.2010.09.048 [4], have been used to create stable complexes. Here we present the data obtained of the binding characterization of the Octarellin V.1 with the crystallization helpers by isothermal titration calorimetry.

  1. Fermionic counting of RSOS states and Virasoro character formulas for the unitary minimal series M( v, v + 1): Exact results

    Science.gov (United States)

    Berkovich, Alexander

    1994-12-01

    The Hilbert space of an RSOS model, introduced by Andrews, Baxter, and Forrester, can be viewed as a space of sequences (paths) { a0, a1,…, aL}, with aj-integers restricted by 1 ≤ aj ≤ v, | aj - aj+1 |=1, a0 ≡ s, aL ≡ r. In this paper we introduce different basis which, as shown here, has the same dimension as that of an RSOS model. This basis appears naturally in the Bethe ansatz calculations of the spin ( v-1)/2 XXZ model. Following McCoy et al., we call this basis fermionic (FB). Our first theorem Dim(FB) = Dim(RSOS - basis) can be succinctly expressed in terms of some identities for binomial coefficients. Remarkably, these binomial identities can be q-deformed. Here, we give a simple proof of these q-binomial identities in the spirit of Schur's proof of the Rogers-Ramanujan identities. Notably, the proof involves only the elementary recurrences for the q-binomial coefficients and a few creative observations. Finally, taking the limit L → ∞ in these q-identities, we derive an expression for the character formulas of the unitary minimal series M( v, v + 1) "Bosonic Sum ≡ Fermionic Sum". Here, Bosonic Sum denotes Rocha-Caridi representation ( Xr, s=1 v, v+1 ( q)) and Fermionic Sum stands for the companion representation recently conjectured by the McCoy group.

  2. Spatial and temporal characteristics of V1 microstimulation during chronic implantation of a microelectrode array in a behaving macaque

    Science.gov (United States)

    Davis, T. S.; Parker, R. A.; House, P. A.; Bagley, E.; Wendelken, S.; Normann, R. A.; Greger, B.

    2012-12-01

    Objective. It has been hypothesized that a vision prosthesis capable of evoking useful visual percepts can be based upon electrically stimulating the primary visual cortex (V1) of a blind human subject via penetrating microelectrode arrays. As a continuation of earlier work, we examined several spatial and temporal characteristics of V1 microstimulation. Approach. An array of 100 penetrating microelectrodes was chronically implanted in V1 of a behaving macaque monkey. Microstimulation thresholds were measured using a two-alternative forced choice detection task. Relative locations of electrically-evoked percepts were measured using a memory saccade-to-target task. Main results. The principal finding was that two years after implantation we were able to evoke behavioural responses to electric stimulation across the spatial extent of the array using groups of contiguous electrodes. Consistent responses to stimulation were evoked at an average threshold current per electrode of 204 ± 49 µA (mean ± std) for groups of four electrodes and 91 ± 25 µA for groups of nine electrodes. Saccades to electrically-evoked percepts using groups of nine electrodes showed that the animal could discriminate spatially distinct percepts with groups having an average separation of 1.6 ± 0.3 mm (mean ± std) in cortex and 1.0° ± 0.2° in visual space. Significance. These results demonstrate chronic perceptual functionality and provide evidence for the feasibility of a cortically-based vision prosthesis for the blind using penetrating microelectrodes.

  3. Elementary properties of CaV1.3 Ca(2+) channels expressed in mouse cochlear inner hair cells.

    Science.gov (United States)

    Zampini, Valeria; Johnson, Stuart L; Franz, Christoph; Lawrence, Neil D; Münkner, Stefan; Engel, Jutta; Knipper, Marlies; Magistretti, Jacopo; Masetto, Sergio; Marcotti, Walter

    2010-01-01

    Mammalian cochlear inner hair cells (IHCs) are specialized to process developmental signals during immature stages and sound stimuli in adult animals. These signals are conveyed onto auditory afferent nerve fibres. Neurotransmitter release at IHC ribbon synapses is controlled by L-type Ca(V)1.3 Ca(2+) channels, the biophysics of which are still unknown in native mammalian cells. We have investigated the localization and elementary properties of Ca(2+) channels in immature mouse IHCs under near-physiological recording conditions. Ca(V)1.3 Ca(2+) channels at the cell pre-synaptic site co-localize with about half of the total number of ribbons present in immature IHCs. These channels activated at about 70 mV, showed a relatively short first latency and weak inactivation, which would allow IHCs to generate and accurately encode spontaneous Ca(2+) action potential activity characteristic of these immature cells. The Ca(V)1.3 Ca(2+) channels showed a very low open probability (about 0.15 at 20 mV: near the peak of an action potential). Comparison of elementary and macroscopic Ca(2+) currents indicated that very few Ca(2+) channels are associated with each docked vesicle at IHC ribbon synapses. Finally, we found that the open probability of Ca(2+) channels, but not their opening time, was voltage dependent. This finding provides a possible correlation between presynaptic Ca(2+) channel properties and the characteristic frequency/amplitude of EPSCs in auditory afferent fibres.

  4. CP determination and tests for CP or P violation by the V1V2 decay mode

    International Nuclear Information System (INIS)

    Nelson, C.A.

    1984-01-01

    A decay mode such as phiphi, UPSILONUPSILON, K/sup asterisk+/K/sup asterisk-/, or D/sup asterisk+/D/sup asterisk-/ can be used to distinguish between a neutral spin-0 technipion and a neutral spin-0 Higgs particle. By this generalization of phiphi parity test, the CP eigenvalue γ/sub C/P can be determined for an X particle of any spin J which decays CP invariantly into VV, or VV-bar, where each vector meson either decays into two spin-0 bosons, or is ω. The absence in a VV, or VV-bar, decay channel of sin2phi and sinphi terms in the azimuthal distribution is due to CP invariance and/or P invariance. For a V 1 V 2 decay channel without a V 1 bold-arrow-left-rightV 2 exchange property, and in a mode like K/sup asterisk+/K /sup asterisk0/, such terms would imply that P is violated. For a V 1 V 2 mode such as phiω where each vector meson is its own antiparticle, such terms would imply that both P and CP are violated; when CP invariance holds, the γ/sub C/P(-)/sup J/ eigenvalue of X can be determined provided certain amplitudes do not accidentally vanish

  5. NaV1.6a is required for normal activation of motor circuits normally excited by tactile stimulation

    Science.gov (United States)

    Low, Sean E.; Zhou, Weibin; Choong, Xinling; Saint-Amant, Louis; Sprague, Shawn M.; Hirata, Hiromi; Cui, Wilson W.; Hume, Richard I.; Kuwada, John Y.

    2010-01-01

    A screen for zebrafish motor mutants identified two non-complementing alleles of a recessive mutation that were named non-active (navmi89 and navmi130). nav embryos displayed diminished spontaneous and touch-evoked escape behaviors during the first three days of development. Genetic mapping identified the gene encoding NaV1.6a (scn8aa) as a potential candidate for nav. Subsequent cloning of scn8aa from the two alleles of nav uncovered two missense mutations in NaV1.6a that eliminated channel activity when assayed heterologously. Furthermore the injection of RNA encoding wild type scn8aa rescued the nav mutant phenotype indicating that scn8aa was the causative gene of nav. In vivo electrophysiological analysis of the touch-evoked escape circuit indicated that voltage-dependent inward current was decreased in mechanosensory neurons in mutants, but they were able to fire action potentials. Furthermore tactile stimulation of mutants activated some neurons downstream of mechanosensory neurons but failed to activate the swim locomotor circuit in accord with the behavioral response of initial escape contractions but no swimming. Thus mutant mechanosensory neurons appeared to respond to tactile stimulation but failed to initiate swimming. Interestingly fictive swimming could be initiated pharmacologically suggesting that a swim circuit was present in mutants. These results suggested that NaV1.6a was required for touch-induced activation of the swim locomotor network. PMID:20225246

  6. Identification of immunogenic proteins in Treponema phagedenis-like strain V1 from digital dermatitis lesions by phage display.

    Science.gov (United States)

    Rosander, Anna; Guss, Bengt; Frykberg, Lars; Björkman, Camilla; Näslund, Katarina; Pringle, Märit

    2011-12-15

    Digital dermatitis (DD) is a contagious claw disease causing lameness in cattle, affecting both animal welfare and economics. In this study, shotgun phage display was used to identify immunogenic proteins in a strain (V1) of the Treponema phylotype closely related to Treponema phagedenis, indicated as a key agent in the pathogenesis of DD. A genomic phage library was constructed and selected against antibodies from a rabbit immunized with live strain V1 bacteria. A homolog to the immunogenic protein TmpA of Treponema pallidum subsp. pallidum was identified, as well as a putative phage tail tape measure protein (Ttm), and a putative proline-rich repeat lipoprotein (PrrA). The complete amino acid sequences of these proteins were predicted from a genomic sequence of strain V1 generated by 454 Sequencing™. The presence of these genes in ten Treponema spp. field isolates was investigated by PCR. The tmpA and ttm genes were detected in all T. phagedenis-like isolates while prrA was detected in four out of seven. None of the genes were detected in the three Treponema pedis isolates investigated. Recombinant proteins were produced and used in indirect ELISAs. For all three proteins, a majority of serum samples from cattle with DD (n=8) showed higher optical density values than samples from cattle without DD (n=7). Copyright © 2011 Elsevier B.V. All rights reserved.

  7. Improvement in light-output efficiency of near-ultraviolet InGaN-GaN LEDs fabricated on stripe patterned sapphire substrates

    International Nuclear Information System (INIS)

    Lee, Y.J.; Hsu, T.C.; Kuo, H.C.; Wang, S.C.; Yang, Y.L.; Yen, S.N.; Chu, Y.T.; Shen, Y.J.; Hsieh, M.H.; Jou, M.J.; Lee, B.J.

    2005-01-01

    InGaN/GaN multi-quantum wells near ultraviolet light-emitting diodes (LEDs) were fabricated on a patterned sapphire substrate (PSS) with parallel stripe along the sapphire direction by using low-pressure metal-organic chemical vapor deposition (MOCVD). The forward- and reverse-bias electrical characteristics of the stripe PSS LEDs are, respectively, similar and better than those of conventional LEDs on sapphire substrate. The output power of the epoxy package of stripe PSS LED was 20% higher than that of the conventional LEDs. The enhancement of output power is due not only to the reduction of dislocation density but also to the release of the guided light in LEDs by the geometric shape of the stripe PSS, according to the ray-tracing analysis

  8. Characterization of the Wheat Stripe Rust (Puccinia striiformis f. sp. tritici) Fungal Effector Candidate PEC6 and Its Corresponding Host Targets

    DEFF Research Database (Denmark)

    Liu, Changhai

    Stripe rust caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most important fungal diseases on wheat worldwide and a serious threat to wheat production. Understanding the plant-microbe interaction mechanism is the basic step to assist future plant breeding aiming at increasing...... disease resistance. Based on the sequenced stripe rust fungus genome, several hundreds of small, secreted candidates for effector proteins are predicted. Effectors are believed to be pivotal for fungal pathogenicity with key roles in suppressing host defense. Thus, identifying key effectors...... and understanding their mechanisms of action is fundamentally important to guide future fights against the stripe rust disease. In this PhD project, I studied the potential function of six stripe rust fungal effector candidates which are highly expressed in haustoria, by employing the Pseudomonas fluorescens Et...

  9. Atypical colororation in the yellow-striped poisonous frog, Dendrobates truncatus (Cope, 1861), in the Colombian Magdalena river valley

    OpenAIRE

    Rivera Prieto, Diego A.; Marín C., David

    2017-01-01

    Herein we report an atypical coloration in one individual of the yellow-striped poisonous frog, Dendrobates truncatus, in Colombian Magdalena middle valley. The adult individual presented leucism, a rare phenomenon occurs in nature or at very low frequencies

  10. Prevalence of agglutinating antibodies to Toxoplasma gondii in striped skunks (Mephitis mephitis), opossums (Didelphis virginiana), and raccoons (Procyon lotor) from Connecticut

    OpenAIRE

    Mitchell, S. M.; Richardson, D. J.; Lindsay, D. S.

    2006-01-01

    The prevalence of agglutinating antibodies to Toxoplasma gondii was examined in striped skunks (Mephitis mephitis), opossums (Didelphis virginiana), and raccoons (Procyon lotor) from 8 cities in Connecticut. Ten (42%) of the 24 striped skunks, 2 of 7 (29%) opossums, and 12 of 12 (100%) raccoons were positive at dilutions of 1:50 or greater. These results suggest that T. gondii is prevalent in the environment, or prey items, or both, of these omnivores in Connecticut.

  11. Prevalence of agglutinating antibodies to Toxoplasma gondii in striped skunks (Mephitis mephitis), opossums (Didelphis virginiana), and raccoons (Procyon lotor) from Connecticut.

    Science.gov (United States)

    Mitchell, Sheila M; Richardson, Dennis J; Lindsay, David S

    2006-06-01

    The prevalence of agglutinating antibodies to Toxoplasma gondii was examined in striped skunks (Mephitis mephitis), opossums (Didelphis virginiana), and raccoons (Procyon lotor) from 8 cities in Connecticut. Ten (42%) of the 24 striped skunks, 2 of 7 (29%) opossums, and 12 of 12 (100%) raccoons were positive at dilutions of 1:50 or greater. These results suggest that T. gondii is prevalent in the environment, or prey items, or both, of these omnivores in Connecticut.

  12. Geographic distribution and spatial differentiation in the color pattern of abdominal stripes of the Neotropical stingless bee Melipona quadrifasciata (Hymenoptera: Apidae)

    OpenAIRE

    Batalha-Filho, Henrique; Melo, Gabriel A. R.; Waldschmidt, Ana M.; Campos, Lucio A. O.; Fernandes-Salomão, Tânia M.

    2009-01-01

    Melipona quadrifasciata Lepeletier, 1836, regionally known as "mandaçaia", has been traditionally divided in two distinct subspecies: M. quadrifasciata anthidioides and M. quadrifasciata quadrifasciata. The main difference between the subspecies refers to the yellow metasomal stripes which are continuous in M. q. quadrifasciata and discontinuous in M. q. anthidioides. This study investigated the geographic differentiation in the metasomal stripes and characterized the restriction sites in the...

  13. Genome-wide association mapping for stripe rust (Puccinia striiformis F. sp. tritici) in US Pacific Northwest winter wheat (Triticum aestivum L.).

    Science.gov (United States)

    Naruoka, Y; Garland-Campbell, K A; Carter, A H

    2015-06-01

    Potential novel and known QTL for race-specific all-stage and adult plant resistance to stripe rust were identified by genome-wide association mapping in the US PNW winter wheat accessions. Stripe rust (Puccinia striiformis F. sp. tritici; also known as yellow rust) is a globally devastating disease of wheat (Triticum aestivum L.) and a major threat to wheat production in the US Pacific Northwest (PNW), therefore both adult plant and all-stage resistance have been introduced into the winter wheat breeding programs in the PNW. The goal of this study was to identify quantitative trait loci (QTL) and molecular markers for these resistances through genome-wide association (GWAS) mapping in winter wheat accessions adapted to the PNW. Stripe rust response for adult plants was evaluated in naturally occurring epidemics in a total of nine environments in Washington State, USA. Seedling response was evaluated with three races under artificial inoculation in the greenhouse. The panel was genotyped with the 9K Illumina Wheat single nucleotide polymorphism (SNP) array and additional markers linked to previously reported genes and QTL for stripe rust resistance. The population was grouped into three sub-populations. Markers linked to Yr17 and previously reported QTL for stripe rust resistance were identified on chromosomes 1B, 2A, and 2B. Potentially novel QTL associated with race-specific seedling response were identified on chromosomes 1B and 1D. Potentially novel QTL associated with adult plant response were located on chromosomes 2A, 2B, 3B, 4A, and 4B. Stripe rust was reduced when multiple alleles for resistance were present. The resistant allele frequencies were different among sub-populations in the panel. This information provides breeders with germplasm and closely linked markers for stripe rust resistance to facilitate the transfer of multiple loci for durable stripe rust resistance into wheat breeding lines and cultivars.

  14. rapidSTRIPE H1N1 Test for Detection of the Pandemic Swine Origin Influenza A (H1N1) Virus▿

    OpenAIRE

    Patel, Pranav; Graser, Elmara; Robst, Stephan; Hillert, Roger; Meye, Axel; Hillebrand, Timo; Niedrig, Matthias

    2011-01-01

    The rapidSTRIPE H1N1 test, based on a nucleic acid lateral-flow assay, has been developed for diagnosis of a swine-origin influenza A (H1N1) virus. This test is simple and cost-effective and allows specific detection of the S-OIV A (H1N1) virus from swab sampling to final detection on a lateral-flow stripe within 2 to 3 h.

  15. Crosstalk reduction in large-scale autostereoscopic 3D-LED display based on black-stripe occupation ratio

    Science.gov (United States)

    Zeng, Xiang-Yao; Zhou, Xiong-Tu; Guo, Tai-Liang; Yang, Lan; Chen, En-Guo; Zhang, Yong-Ai

    2017-04-01

    Autostereoscopic 3D-LED displays using parallax barriers have several advantages. However, conventional designs do not consider the black stripes of regular LED panels. These cause immeasurable crosstalk owing to excess light from adjacent sub-pixels separated by the panels. To reduce the crosstalk in large-scale displays, we design a barrier in which the black-stripe occupation ratio is defined to quantify the crosstalk level in the LED system. A prototype is assembled and analyzed based on a three-in-one pixel LED-chip panel for a dual-viewpoint display. The improved parallax barrier meets the design requirements and achieves a low crosstalk level. Simulation and experiment results verify the effectiveness of the crosstalk-reduced design.

  16. Candidatus Renichlamydia lutjani, a Gram-negative bacterium in internal organs of blue striped snapper Lutjanus kasmira from Hawaii

    Science.gov (United States)

    Corsaro, Daniele; Work, Thierry M.

    2012-01-01

    The blue-striped snapper Lutjanus kasmira (Perciformes, Lutjanidae) are cosmopolitan in the Indo-Pacific but were introduced into Oahu, Hawaii, USA, in the 1950s and have since colonized most of the archipelago. Studies of microparasites in blue-striped snappers from Hawaii revealed chlamydia-like organisms (CLO) infecting the spleen and kidney, characterized by intracellular basophilic granular inclusions containing Gram-negative and Gimenez-positive bacteria similar in appearance to epitheliocysts when seen under light microscopy. We provide molecular evidence that CLO are a new member of Chlamydiae, i.e. Candidatus Renichlamydia lutjani, that represents the first reported case of chlamydial infection in organs other than the gill in fishes.

  17. Formation of periodic size-segregated stripe pattern via directed self-assembly of binary colloids and its mechanism

    Science.gov (United States)

    Das, Sayantan; Duraia, El-Shazly M.; Velev, Orlin D.; Amiri, Maedeh D.; Beall, Gary W.

    2018-03-01

    Convective self-assembly, well known for producing highly ordered monolayer structures, has been used in this study to create novel surface patterns using the binary mixture of colloids. We demonstrate that different patterns form, based on the size ratio (Small/Large) of the particles, and particles volume ratio. Surprisingly, certain binary particle mixtures resulted in spontaneous size based segregation. In some cases, the particle separation occurred along the direction of the meniscus contact line, and by the mere design of the process, we created periodic stripe patterns with controlled width. The particle volume fraction, size differences, surface tension, and the curvature of the meniscus played a crucial factor in the segregation process as well as in determining the width of each of the stripes. Furthermore, based on both empirical and numerical analysis, a mechanism for size-based segregation of particles via directed self-assembly is proposed.

  18. Antiphase boundaries, inversion, and ferroelastic domains in the striped-type superstructure of γ-brass Cu-Al alloys

    Science.gov (United States)

    Koyama, Y.; Hatano, M.; Tanimura, M.

    1996-05-01

    Features of the striped-type superstructure in γ-brass Cu-Al alloys have been investigated mainly by transmission electron microscopy in order to understand the role of a rhombohedral distortion in its stability. From dark field images taken from alloys exhibiting the superstructure, it was found that there exist two types of ferroelastic rhombohedral domains, which are in a twin relation. In other words, the superstructure is characterized by a periodic array of the ferroelastic domains as well as inversion antiphase boundaries. Because charge density waves should be responsible for the formation of the superstructure, as suggested in our previous paper [Phys. Rev. B 40, 5378 (1989)], the rhombohedral distortion must play a crucial role in their appearance. Presumably the distortion enlarges parallel portions of the Fermi surface. On the basis of the present experimental data, the interplay between the striped-type superstructure and the rhombohedral γ-brass structure is also discussed.

  19. Influence of stripe rust infection on the photosynthetic characteristics and antioxidant system of susceptible and resistant wheat cultivars at the adult plant stage.

    Science.gov (United States)

    Chen, Yang-Er; Cui, Jun-Mei; Su, Yan-Qiu; Yuan, Shu; Yuan, Ming; Zhang, Huai-Yu

    2015-01-01

    Wheat stripe rust (Puccinia striiformis f. sp. tritici, Pst), is one of the most serious diseases of wheat (Triticum aestivum L.) worldwide. To gain a better understanding of the protective mechanism against stripe rust at the adult plant stage, the differences in photosystem II and antioxidant enzymatic systems between susceptible and resistant wheat in response to stripe rust disease (P. striiformis) were investigated. We found that chlorophyll fluorescence and the activities of the antioxidant enzymes were higher in resistant wheat than in susceptible wheat after stripe rust infection. Compared with the susceptible wheat, the resistant wheat accumulated a higher level of D1 protein and a lower level of reactive oxygen species after infection. Furthermore, our results demonstrate that D1 and light-harvesting complex II (LHCII) phosphorylation are involved in the resistance to stripe rust in wheat. The CP29 protein was phosphorylated under stripe rust infection, like its phosphorylation in other monocots under environmental stresses. More extensive damages occur on the thylakoid membranes in the susceptible wheat compared with the resistant wheat. The findings provide evidence that thylakoid protein phosphorylation and antioxidant enzyme systems play important roles in plant responses and defense to biotic stress.

  20. 75 FR 54627 - ICLUS v1.3 User's Manual: ArcGIS Tools and Datasets for Modeling U.S. Housing Density Growth

    Science.gov (United States)

    2010-09-08

    ... AGENCY ICLUS v1.3 User's Manual: ArcGIS Tools and Datasets for Modeling U.S. Housing Density Growth... (GIS) tool and final user's guide titled, ``ICLUS v1.3 User's Manual: ArcGIS Tools and Datasets for.... ADDRESSES: ``ICLUS v1.3 User's Manual: ArcGIS Tools and Datasets for Modeling U.S. Housing Density Growth...